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Sample records for kilpla mehed ei

  1. EI Handbook. Second Edition.

    ERIC Educational Resources Information Center

    Education International, Brussels (Belgium).

    The publication contains organizational information relating to Education International (EI). Included are lists of the EI Executive Board, EI Headquarters staff, and EI Regional Officers; for Constitution and By-Laws of EI; By-Laws for four of EI's five official regions--Africa, Asia, Europe, and Latin America (North American and the Caribbean is…

  2. Streamlining the EIS Process

    ERIC Educational Resources Information Center

    Josephson, Julian

    1977-01-01

    A new publication service abstracts, indexes, and prepares microfiche of environmental impact statements (EIS). This new service is designed to streamline the EIS process by reducing the cost and time of preparation, by eliminating redundancy of similar statements, and by working with the government to standardize the preparation process. (MA)

  3. OpenEIS Algorithms

    SciTech Connect

    2013-07-29

    The OpenEIS Algorithm package seeks to provide a low-risk path for building owners, service providers and managers to explore analytical methods for improving building control and operational efficiency. Users of this software can analyze building data, and learn how commercial implementations would provide long-term value. The code also serves as a reference implementation for developers who wish to adapt the algorithms for use in commercial tools or service offerings.

  4. OpenEIS. Users Guide

    SciTech Connect

    Kim, Woohyun; Lutes, Robert G.; Katipamula, Srinivas; Haack, Jereme N.; Carpenter, Brandon J.; Akyol, Bora A.; Monson, Kyle E.; Allwardt, Craig H.; Kang, Timothy; Sharma, Poorva

    2015-02-28

    This document is a users guide for OpenEIS, a software code designed to provide standard methods for authoring, sharing, testing, using and improving algorithms for operational building energy efficiency.

  5. 32 CFR 989.20 - Final EIS.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... ENVIRONMENTAL IMPACT ANALYSIS PROCESS (EIAP) § 989.20 Final EIS. (a) If changes in the draft EIS are minor or... analysis is required. (b) The EPF processes all necessary supplements to EISs (40 CFR 1502.9) in the same way as the original Draft and Final EIS, except that a new scoping process is not required. (c)...

  6. Doppler Imaging of EI Eridani

    NASA Astrophysics Data System (ADS)

    Washuettl, Albert; Strassmeier, Klaus G.; Collier-Cameron, Andrew

    We present Doppler images of the rapidly rotating active close binary star EI Eridani. Several Doppler images have been produced since 1984 making use of different versions of the Doppler imaging technique. They all show high-latitude spots surrounding or covering the rotational pole as well as some smaller spots on lower latitudes. The high-latitude/polar spot seems to be long-lived (at least a decade) but changes its shape on comparatively short timescales (of the order of one month). From time to time spots along the stellar equator also occur, but their lifetimes tend to be relatively short (weeks). Furthermore, long-term photometric observations revealed the existence of a magnetic cycle which has been estimated to be around 11 years. We also present time-resolved Doppler images from EI Eri obtained at McMath/NSO in fall 1996 during 70 consecutive nights. The final aim of this program is to investigate the spot evolution over the whole activity cycle.

  7. OpenEIS. Developer Guide

    SciTech Connect

    Lutes, Robert G.; Neubauer, Casey C.; Haack, Jereme N.; Carpenter, Brandon J.; Monson, Kyle E.; Allwardt, Craig H.; Sharma, Poorva; Akyol, Bora A.

    2015-03-31

    The Department of Energy’s (DOE’s) Building Technologies Office (BTO) is supporting the development of an open-source software tool for analyzing building energy and operational data: OpenEIS (open energy information system). This tool addresses the problems of both owners of building data and developers of tools to analyze this data. Building owners and managers have data but lack the tools to analyze it while tool developers lack data in a common format to ease development of reusable data analysis tools. This document is intended for developers of applications and explains the mechanisms for building analysis applications, accessing data, and displaying data using a visualization from the included library. A brief introduction to the visualizations can be used as a jumping off point for developers familiar with JavaScript to produce their own. Several example applications are included which can be used along with this document to implement algorithms for performing energy data analysis.

  8. Development of Emergency Intravehicular Spacesuit (EIS) assembly

    NASA Technical Reports Server (NTRS)

    1973-01-01

    A program was undertaken to develop and test two prototype pressure suits to operate at pressures up to 413 mm Hg (8.0 PSIG). The units were designated Emergency Intravehicular Spacesuits (EIS). Performance requirements, design evolution, testing performed, problems encountered, and final EIS configuration are reported.

  9. 7 CFR 1794.62 - Supplemental EIS.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... (CONTINUED) ENVIRONMENTAL POLICIES AND PROCEDURES Procedure for Environmental Impact Statements § 1794.62... issue an information supplement to a final EIS where RUS determines that the purposes of NEPA are...

  10. 7 CFR 1794.62 - Supplemental EIS.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... (CONTINUED) ENVIRONMENTAL POLICIES AND PROCEDURES Procedure for Environmental Impact Statements § 1794.62... issue an information supplement to a final EIS where RUS determines that the purposes of NEPA are...

  11. 36 CFR 1010.9 - Preparation of an EIS.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false Preparation of an EIS. 1010.9... Preparation of an EIS. (a) Notice of intent. When the Trust decides to prepare an EIS, it shall publish a... lengthy period between the Trust's decision to prepare an EIS and the time of actual preparation, then...

  12. 7 CFR 1794.72 - Adoption of an EIS.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... to meet the standards for an adequate statement for RUS proposed action, RUS may adopt all or a... agency's EIS is adequate, RUS shall adopt that agency's EIS as its final EIS. RUS and the applicant shall... its adequacy. (c) If the adopted EIS is generally available and meets RUS standards, RUS shall have a...

  13. 32 CFR 989.19 - Draft EIS.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... interested agencies at least 7 calendar days prior to publication of the Notice of Availability (NOA) in the... least 45 days starting from the publication date of the NOA of the draft EIS in the Federal Register... place no sooner than 15 days after the Federal Register publication of the NOA and at least 15...

  14. 32 CFR 989.19 - Draft EIS.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... interested agencies at least 7 calendar days prior to publication of the Notice of Availability (NOA) in the... least 45 days starting from the publication date of the NOA of the draft EIS in the Federal Register... place no sooner than 15 days after the Federal Register publication of the NOA and at least 15...

  15. 32 CFR 989.19 - Draft EIS.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... interested agencies at least 7 calendar days prior to publication of the Notice of Availability (NOA) in the... least 45 days starting from the publication date of the NOA of the draft EIS in the Federal Register... place no sooner than 15 days after the Federal Register publication of the NOA and at least 15...

  16. 32 CFR 989.19 - Draft EIS.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... interested agencies at least 7 calendar days prior to publication of the Notice of Availability (NOA) in the... least 45 days starting from the publication date of the NOA of the draft EIS in the Federal Register... place no sooner than 15 days after the Federal Register publication of the NOA and at least 15...

  17. 32 CFR 989.19 - Draft EIS.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... interested agencies at least 7 calendar days prior to publication of the Notice of Availability (NOA) in the... least 45 days starting from the publication date of the NOA of the draft EIS in the Federal Register... place no sooner than 15 days after the Federal Register publication of the NOA and at least 15...

  18. 7 CFR 1794.72 - Adoption of an EIS.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 12 2014-01-01 2013-01-01 true Adoption of an EIS. 1794.72 Section 1794.72... AGRICULTURE (CONTINUED) ENVIRONMENTAL POLICIES AND PROCEDURES Adoption of Environmental Documents § 1794.72 Adoption of an EIS. (a) Where RUS determines that an existing Federal EIS requires additional information...

  19. 7 CFR 1794.72 - Adoption of an EIS.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 12 2012-01-01 2012-01-01 false Adoption of an EIS. 1794.72 Section 1794.72... AGRICULTURE (CONTINUED) ENVIRONMENTAL POLICIES AND PROCEDURES Adoption of Environmental Documents § 1794.72 Adoption of an EIS. (a) Where RUS determines that an existing Federal EIS requires additional information...

  20. 7 CFR 1794.72 - Adoption of an EIS.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 12 2013-01-01 2013-01-01 false Adoption of an EIS. 1794.72 Section 1794.72... AGRICULTURE (CONTINUED) ENVIRONMENTAL POLICIES AND PROCEDURES Adoption of Environmental Documents § 1794.72 Adoption of an EIS. (a) Where RUS determines that an existing Federal EIS requires additional information...

  1. 12 CFR 1815.109 - Preparation of an EIS.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 10 2014-01-01 2014-01-01 false Preparation of an EIS. 1815.109 Section 1815.109 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY ENVIRONMENTAL QUALITY § 1815.109 Preparation of an EIS. (a) If the Fund determines that an EIS should...

  2. 12 CFR 1815.109 - Preparation of an EIS.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 9 2012-01-01 2012-01-01 false Preparation of an EIS. 1815.109 Section 1815.109 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY ENVIRONMENTAL QUALITY § 1815.109 Preparation of an EIS. (a) If the Fund determines that an EIS should...

  3. 12 CFR 1815.109 - Preparation of an EIS.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 7 2011-01-01 2011-01-01 false Preparation of an EIS. 1815.109 Section 1815.109 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY ENVIRONMENTAL QUALITY § 1815.109 Preparation of an EIS. (a) If the Fund determines that an EIS should...

  4. 7 CFR 1794.72 - Adoption of an EIS.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Adoption of an EIS. 1794.72 Section 1794.72... AGRICULTURE (CONTINUED) ENVIRONMENTAL POLICIES AND PROCEDURES Adoption of Environmental Documents § 1794.72 Adoption of an EIS. (a) Where RUS determines that an existing Federal EIS requires additional information...

  5. EI competencies as a related but different characteristic than intelligence.

    PubMed

    Boyatzis, Richard E; Batista-Foguet, Joan M; Fernández-I-Marín, Xavier; Truninger, Margarida

    2015-01-01

    Amid the swarm of debate about emotional intelligence (EI) among academics are claims that cognitive intelligence, or general mental ability (g), is a stronger predictor of life and work outcomes as well as the counter claims that EI is their strongest predictor. Nested within the tempest in a teapot are scientific questions as to what the relationship is between g and EI. Using a behavioral approach to EI, we examined the relationship of a parametric measure of g as the person's GMAT scores and collected observations from others who live and work with the person as to the frequency of his or her EI behavior, as well as the person's self-assessment. The results show that EI, as seen by others, is slightly related to g, especially for males with assessment from professional relations. Further, we found that cognitive competencies are more strongly related to GMAT than EI competencies. For observations from personal relationships or self-assessment, there is no relationship between EI and GMAT. Observations from professional relations reveal a positive relationship between cognitive competencies and GMAT and EI and GMAT for males, but a negative relationship between EI and GMAT for females.

  6. EI competencies as a related but different characteristic than intelligence

    PubMed Central

    Boyatzis, Richard E.; Batista-Foguet, Joan M.; Fernández-i-Marín, Xavier; Truninger, Margarida

    2015-01-01

    Amid the swarm of debate about emotional intelligence (EI) among academics are claims that cognitive intelligence, or general mental ability (g), is a stronger predictor of life and work outcomes as well as the counter claims that EI is their strongest predictor. Nested within the tempest in a teapot are scientific questions as to what the relationship is between g and EI. Using a behavioral approach to EI, we examined the relationship of a parametric measure of g as the person’s GMAT scores and collected observations from others who live and work with the person as to the frequency of his or her EI behavior, as well as the person’s self-assessment. The results show that EI, as seen by others, is slightly related to g, especially for males with assessment from professional relations. Further, we found that cognitive competencies are more strongly related to GMAT than EI competencies. For observations from personal relationships or self-assessment, there is no relationship between EI and GMAT. Observations from professional relations reveal a positive relationship between cognitive competencies and GMAT and EI and GMAT for males, but a negative relationship between EI and GMAT for females. PMID:25713545

  7. Microfabricated EIS biosensor for detection of DNA

    NASA Astrophysics Data System (ADS)

    Taing, M.; Sweatman, D.

    2006-01-01

    This paper focuses on the design of an EIS (electrolyte on insulator on Silicon) structure as a detection method for pathogenic DNA. Current rapid detection methods rely on fluorescent labeling to determine binding affinity. Fluorescent quenching is seen by a change in activity as opposed to non-quenched states. Sensitive optical equipment is required to detect and distinguish these colour changes because they cannot be seen by the naked eye. The disadvantages of this is (1) a portable, independent device cannot be made since samples have to be brought back to the benchtop and (2) the obvious cost of acquiring and maintaining these optical detection systems. A low cost, portable electrical detection method has been investigated. The EIS structure (Electrolyte on Insulator on Silicon) provides a novel, label-free and simple to fabricate way to make a small field effect DNA detection sensor. The sensor responds to fluctuating capacitances caused by a depletion layer thickness change at the surface of the silicon substrate as a result of DNA adsorption onto the dielectric oxide/APTES (Aminopropylthioxysilane) surface. As DNA molecules diffuse to the sensor surface, they are bound to their complimentary capture probes. The negative charge exhibited by the DNA forces negative charge carriers in the silicon substrate to move away from the surface. This causes a depletion layer in n-type substrate to thicken and for a p-type to thin and can be observed as a change in capacitance. A low ionic solution strength will ensure that counter-ions do not affect the sensor measurements. The EIS sensor is designed to be later integrated into a complete lab on chip solution. A full lab on chip can incorporate the sensor to perform DNA quantity based measurements. Nucleic acids can be amplified by the on chip PCR system and then fed into the sensor to work out the DNA concentration. The sensor surface contains capture probes that will bind to the pathogen. They are held onto the

  8. Open Energy Info (OpenEI) (Fact Sheet)

    SciTech Connect

    Not Available

    2010-12-01

    The Open Energy Information (OpenEI.org) initiative is a free, open-source, knowledge-sharing platform. OpenEI was created to provide access to data, models, tools, and information that accelerate the transition to clean energy systems through informed decisions.

  9. 33 CFR 230.13 - Environmental Impact Statement (EIS).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Environmental Impact Statement..., DEPARTMENT OF DEFENSE PROCEDURES FOR IMPLEMENTING NEPA § 230.13 Environmental Impact Statement (EIS). An EIS... issues and impacts. The transmittal letter to EPA as well as the cover sheet should clearly identify the...

  10. 36 CFR § 1010.9 - Preparation of an EIS.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ....9 Section § 1010.9 Parks, Forests, and Public Property PRESIDIO TRUST ENVIRONMENTAL QUALITY § 1010.... (c) Supplemental environmental impact statements. The Trust may supplement a draft or final EIS at... changes are proposed to an action analyzed in the draft or final EIS that are relevant to environmental...

  11. 36 CFR 1010.9 - Preparation of an EIS.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Section 1010.9 Parks, Forests, and Public Property PRESIDIO TRUST ENVIRONMENTAL QUALITY § 1010.9...) Supplemental environmental impact statements. The Trust may supplement a draft or final EIS at any time. The... proposed to an action analyzed in the draft or final EIS that are relevant to environmental concerns; (2...

  12. 36 CFR 1010.9 - Preparation of an EIS.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Section 1010.9 Parks, Forests, and Public Property PRESIDIO TRUST ENVIRONMENTAL QUALITY § 1010.9...) Supplemental environmental impact statements. The Trust may supplement a draft or final EIS at any time. The... proposed to an action analyzed in the draft or final EIS that are relevant to environmental concerns; (2...

  13. 36 CFR 907.9 - Preparation of an EIS.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false Preparation of an EIS. 907.9... ENVIRONMENTAL QUALITY § 907.9 Preparation of an EIS. (a) Notice of intent. When PADC decides to prepare an... 40 CFR 1501.7 and 1508.22 of the CEQ Regulations. (b) Preparation. After determining that...

  14. 36 CFR 907.9 - Preparation of an EIS.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Preparation of an EIS. 907.9... ENVIRONMENTAL QUALITY § 907.9 Preparation of an EIS. (a) Notice of intent. When PADC decides to prepare an... 40 CFR 1501.7 and 1508.22 of the CEQ Regulations. (b) Preparation. After determining that...

  15. DARHT -- an adequate EIS: A NEPA case study

    SciTech Connect

    Webb, M.D.

    1997-08-01

    In April 1996 the US District Court in Albuquerque ruled that the Dual Axis Radiographic Hydrodynamic Test (DARHT) Facility Environmental Impact Statement (EIS), prepared by the Los Alamos Area Office, US Department of Energy (DOE), was adequate. The DARHT EIS had been prepared in the face of a lawsuit in only 10 months, a third of the time usually allotted for a DOE EIS, and for only a small fraction of the cost of a typical DOE EIS, and for only a small fraction of the cost of a typical DOE EIS. It subject was the first major facility to be built in decades for the DOE nuclear weapons stockpile stewardship program. It was the first EIS to be prepared for a proposal at DOE`s Los Alamos National Laboratory since 1979, and the first ever prepared by the Los Alamos Area Office. Much of the subject matter was classified. The facility had been specially designed to minimize impacts to a nearby prehistoric Native American ruin, and extensive consultation with American Indian Pueblos was required. The week that the draft EIS was published Laboratory biologists identified a previously unknown pair of Mexican spotted owls in the immediate vicinity of the project, bringing into play the consultation requirements of the Endangered Species Act. In spite of these obstacles, the resultant DARHT EIS was reviewed by the court and found to meet all statutory and regulatory requirements; the court praised the treatment of the classified material which served as a basis for the environmental analysis.

  16. 36 CFR 907.7 - Determination of requirement for EIS.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... for EIS. 907.7 Section 907.7 Parks, Forests, and Public Property PENNSYLVANIA AVENUE DEVELOPMENT CORPORATION ENVIRONMENTAL QUALITY § 907.7 Determination of requirement for EIS. Determining whether to prepare an environmental impact statement is the first step in applying the NEPA process. In deciding whether...

  17. 7 CFR 1940.329 - Commenting on other Agencies' EIS's.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... matters. (c) Whenever a State Director has serious concerns over the acceptability of the anticipated... other Agencies' EIS's. (a) State Directors are authorized to comment directly on EIS's prepared by other...) Comments should concentrate on those matters of primary importance to FmHA or its successor agency under...

  18. 33 CFR 230.13 - Environmental Impact Statement (EIS).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Environmental Impact Statement..., DEPARTMENT OF DEFENSE PROCEDURES FOR IMPLEMENTING NEPA § 230.13 Environmental Impact Statement (EIS). An EIS... issues and impacts. The transmittal letter to EPA as well as the cover sheet should clearly identify the...

  19. 33 CFR 230.13 - Environmental Impact Statement (EIS).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Environmental Impact Statement..., DEPARTMENT OF DEFENSE PROCEDURES FOR IMPLEMENTING NEPA § 230.13 Environmental Impact Statement (EIS). An EIS... issues and impacts. The transmittal letter to EPA as well as the cover sheet should clearly identify the...

  20. 33 CFR 230.13 - Environmental Impact Statement (EIS).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Environmental Impact Statement..., DEPARTMENT OF DEFENSE PROCEDURES FOR IMPLEMENTING NEPA § 230.13 Environmental Impact Statement (EIS). An EIS... issues and impacts. The transmittal letter to EPA as well as the cover sheet should clearly identify the...

  1. 33 CFR 230.13 - Environmental Impact Statement (EIS).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Environmental Impact Statement..., DEPARTMENT OF DEFENSE PROCEDURES FOR IMPLEMENTING NEPA § 230.13 Environmental Impact Statement (EIS). An EIS... issues and impacts. The transmittal letter to EPA as well as the cover sheet should clearly identify the...

  2. 32 CFR 651.43 - Format of the EIS.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Format of the EIS. 651.43 Section 651.43 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) ENVIRONMENTAL QUALITY ENVIRONMENTAL ANALYSIS OF ARMY ACTIONS (AR 200-2) Environmental Impact Statement § 651.43 Format of the EIS. The...

  3. 32 CFR 651.43 - Format of the EIS.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 4 2011-07-01 2011-07-01 false Format of the EIS. 651.43 Section 651.43 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) ENVIRONMENTAL QUALITY ENVIRONMENTAL ANALYSIS OF ARMY ACTIONS (AR 200-2) Environmental Impact Statement § 651.43 Format of the EIS. The...

  4. 32 CFR 651.43 - Format of the EIS.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 4 2014-07-01 2013-07-01 true Format of the EIS. 651.43 Section 651.43 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) ENVIRONMENTAL QUALITY ENVIRONMENTAL ANALYSIS OF ARMY ACTIONS (AR 200-2) Environmental Impact Statement § 651.43 Format of the EIS. The...

  5. 32 CFR 651.43 - Format of the EIS.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 4 2012-07-01 2011-07-01 true Format of the EIS. 651.43 Section 651.43 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) ENVIRONMENTAL QUALITY ENVIRONMENTAL ANALYSIS OF ARMY ACTIONS (AR 200-2) Environmental Impact Statement § 651.43 Format of the EIS. The...

  6. 32 CFR 651.43 - Format of the EIS.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 4 2013-07-01 2013-07-01 false Format of the EIS. 651.43 Section 651.43 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) ENVIRONMENTAL QUALITY ENVIRONMENTAL ANALYSIS OF ARMY ACTIONS (AR 200-2) Environmental Impact Statement § 651.43 Format of the EIS. The...

  7. EIS No. 20100312 EIS Comanche Peak Nuclear Power Plant Units 3 and 4

    SciTech Connect

    Bjornstad, David J

    2010-08-01

    In accordance with Section 309(a) of the Clean Air Act, EPA is required to make its comments on EISs issued by other Federal agencies public. Historically, EPA has met this mandate by publishing weekly notices of availability of EPA comments, which includes a brief summary of EPA's comment letters, in the Federal Register. Since February 2008, EPA has been including its comment letters on EISs on its Web site at: http://www.epa.gov/compliance/nepa/eisdata.html. Including the entire EIS comment letters on the Web site satisfies the Section 309(a) requirement to make EPA's comments on EISs available to the public. Accordingly, on March 31, 2010, EPA discontinued the publication of the notice of availability of EPA comments in the Federal Register. EIS No. 20100312, Draft EIS, NRC, TX, Comanche Peak Nuclear Power Plant Units 3 and 4, Application for Combined Licenses (COLs) for Construction Permits and Operating Licenses, (NUREG-1943), Hood and Somervell Counties, TX, Comment Period Ends: 10/26/2010.

  8. The Influence of Emotional Intelligence (EI) on Coping and Mental Health in Adolescence: Divergent Roles for Trait and Ability EI

    ERIC Educational Resources Information Center

    Davis, Sarah K.; Humphrey, Neil

    2012-01-01

    Theoretically, trait and ability emotional intelligence (EI) should mobilise coping processes to promote adaptation, plausibly operating as personal resources determining choice and/or implementation of coping style. However, there is a dearth of research deconstructing if/how EI impacts mental health via multiple coping strategies in adolescence.…

  9. The Influence of Emotional Intelligence (EI) on Coping and Mental Health in Adolescence: Divergent Roles for Trait and Ability EI

    ERIC Educational Resources Information Center

    Davis, Sarah K.; Humphrey, Neil

    2012-01-01

    Theoretically, trait and ability emotional intelligence (EI) should mobilise coping processes to promote adaptation, plausibly operating as personal resources determining choice and/or implementation of coping style. However, there is a dearth of research deconstructing if/how EI impacts mental health via multiple coping strategies in adolescence.…

  10. 36 CFR 1010.9 - Preparation of an EIS.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... human environment. ...) Supplemental environmental impact statements. The Trust may supplement a draft or final EIS at any time. The... the proposed action or its impacts; or (3) Actions are proposed which relate to or are similar to...

  11. Determining the Differential Emission Measure from EIS, XRT, and AIA

    NASA Technical Reports Server (NTRS)

    Winebarger, Amy R.; Warren, H.P.; Schmelz, J.

    2010-01-01

    This viewgraph presentation determines the Differential Emission Measure (DEM) from the EUV Imaging Spectrometer (EIS), X Ray Telescope (XRT), and Atmospheric Imaging Array (AIA). Common observations with Fe, Si, and Ca EIS lines are shown along with observations with Al-mesh, Ti-poly Al-thick and Be-thick XRT filters. Results from these observations are shown to determine what lines and filters are important to better constrain the hot component.

  12. Emotional Intelligence (EI) of Patients with Multiple Sclerosis (MS).

    PubMed

    Ghajarzadeh, Mahsa; Owji, Mahsa; Sauraian, Mohammad Ali; Naser Moghadasi, Abdorreza; Azimi, Amirreza

    2014-11-01

    Multiple sclerosis (MS) is an autoimmune disease that affects physical and emotional aspects of patient's lives. The aim of this study was to evaluate Emotional Intelligence (EI) in cases with MS. One hundred sixty six clinically definite MS and 110 healthy subjects were enrolled in this study. All participants filled valid and reliable Persian version Emotional Quotient inventory (EQ-i) questionnaire, which had been developed due to Bar-On model. Mean EI total score and 12 out of 15 subscales were significantly different between patients and controls. Total EI score and most of its subscales were significantly higher in patients with RR (Relapsing Remitting) than Secondary Progressive (SP) ones. There was significant negative correlation between EDSS and total EI score (rho=-0.4, P<0.001). Multiple linear regression analysis between the EI as a dependent variable and sex, type of disease, level of education, age and marital status as independent variables in patients showed that type of disease and level of education were independent predictors of EI. Emotional intelligence as the ability to behave better and communicate with others should be considered in MS cases as their physical and psychological health are affected by their illness.

  13. Emotional Intelligence (EI) of Patients with Multiple Sclerosis (MS)

    PubMed Central

    GHAJARZADEH, Mahsa; OWJI, Mahsa; SAURAIAN, Mohammad Ali; NASER MOGHADASI, Abdorreza; AZIMI, Amirreza

    2014-01-01

    Abstract Background Multiple sclerosis (MS) is an autoimmune disease that affects physical and emotional aspects of patient’s lives. The aim of this study was to evaluate Emotional Intelligence (EI) in cases with MS. Methods One hundred sixty six clinically definite MS and 110 healthy subjects were enrolled in this study. All participants filled valid and reliable Persian version Emotional Quotient inventory (EQ-i) questionnaire, which had been developed due to Bar-On model. Results Mean EI total score and 12 out of 15 subscales were significantly different between patients and controls. Total EI score and most of its subscales were significantly higher in patients with RR (Relapsing Remitting) than Secondary Progressive (SP) ones. There was significant negative correlation between EDSS and total EI score (rho=-0.4, P<0.001). Multiple linear regression analysis between the EI as a dependent variable and sex, type of disease, level of education, age and marital status as independent variables in patients showed that type of disease and level of education were independent predictors of EI. Conclusion Emotional intelligence as the ability to behave better and communicate with others should be considered in MS cases as their physical and psychological health are affected by their illness. PMID:26060723

  14. 7 CFR 520.7 - Preparation of an Environmental Impact Statement (EIS).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE PROCEDURES FOR IMPLEMENTING NATIONAL ENVIRONMENTAL POLICY ACT § 520.7 Preparation of an Environmental Impact Statement (EIS). (a) Actions requiring EIS. An EIS will... 7 Agriculture 6 2012-01-01 2012-01-01 false Preparation of an Environmental Impact Statement (EIS...

  15. 7 CFR 520.7 - Preparation of an Environmental Impact Statement (EIS).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Preparation of an Environmental Impact Statement (EIS... § 520.7 Preparation of an Environmental Impact Statement (EIS). (a) Actions requiring EIS. An EIS will... affecting the quality of the human environment. In the experience of ARS, an environmental impact statement...

  16. 7 CFR 520.7 - Preparation of an Environmental Impact Statement (EIS).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 6 2013-01-01 2013-01-01 false Preparation of an Environmental Impact Statement (EIS... § 520.7 Preparation of an Environmental Impact Statement (EIS). (a) Actions requiring EIS. An EIS will... affecting the quality of the human environment. In the experience of ARS, an environmental impact...

  17. Biochemical and structural analysis of an Eis family aminoglycoside acetyltransferase from bacillus anthracis.

    PubMed

    Green, Keith D; Biswas, Tapan; Chang, Changsoo; Wu, Ruiying; Chen, Wenjing; Janes, Brian K; Chalupska, Dominika; Gornicki, Piotr; Hanna, Philip C; Tsodikov, Oleg V; Joachimiak, Andrzej; Garneau-Tsodikova, Sylvie

    2015-05-26

    Proteins from the enhanced intracellular survival (Eis) family are versatile acetyltransferases that acetylate amines at multiple positions of several aminoglycosides (AGs). Their upregulation confers drug resistance. Homologues of Eis are present in diverse bacteria, including many pathogens. Eis from Mycobacterium tuberculosis (Eis_Mtb) has been well characterized. In this study, we explored the AG specificity and catalytic efficiency of the Eis family protein from Bacillus anthracis (Eis_Ban). Kinetic analysis of specificity and catalytic efficiency of acetylation of six AGs indicates that Eis_Ban displays significant differences from Eis_Mtb in both substrate binding and catalytic efficiency. The number of acetylated amines was also different for several AGs, indicating a distinct regiospecificity of Eis_Ban. Furthermore, most recently identified inhibitors of Eis_Mtb did not inhibit Eis_Ban, underscoring the differences between these two enzymes. To explain these differences, we determined an Eis_Ban crystal structure. The comparison of the crystal structures of Eis_Ban and Eis_Mtb demonstrates that critical residues lining their respective substrate binding pockets differ substantially, explaining their distinct specificities. Our results suggest that acetyltransferases of the Eis family evolved divergently to garner distinct specificities while conserving catalytic efficiency, possibly to counter distinct chemical challenges. The unique specificity features of these enzymes can be utilized as tools for developing AGs with novel modifications and help guide specific AG treatments to avoid Eis-mediated resistance.

  18. 7 CFR 520.7 - Preparation of an Environmental Impact Statement (EIS).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 6 2014-01-01 2014-01-01 false Preparation of an Environmental Impact Statement (EIS... § 520.7 Preparation of an Environmental Impact Statement (EIS). (a) Actions requiring EIS. An EIS will... affecting the quality of the human environment. In the experience of ARS, an environmental impact statement...

  19. A methodology for post-EIS (environmental impact statement) monitoring

    USGS Publications Warehouse

    Marcus, Linda Graves

    1979-01-01

    A methodology for monitoring the impacts predicted in environmental impact statements (EIS's) was developed using the EIS on phosphate development in southeastern Idaho as a case study. A monitoring system based on this methodology: (1) coordinates a comprehensive, intergovernmental monitoring effort; (2) documents the major impacts that result, thereby improving the accuracy of impact predictions in future EIS's; (3) helps agencies control impacts by warning them when critical impact levels are reached and by providing feedback on the success of mitigating measures; and (4) limits monitoring data to the essential information that agencies need to carry out their regulatory and environmental protection responsibilities. The methodology is presented as flow charts accompanied by tables that describe the objectives, tasks, and products for each work element in the flow chart.

  20. Redesign of substrate specificity and identification of aminoglycoside binding residues of Eis from Mycobacterium tuberculosis

    PubMed Central

    Jennings, Benjamin C.; Labby, Kristin J.; Green, Keith D.; Garneau-Tsodikova, Sylvie

    2013-01-01

    The upsurge of drug-resistant tuberculosis (TB) is an emerging global problem. Increased expression of the enhanced intracellular survival (Eis) protein is responsible for clinical resistance to aminoglycoside (AG) antibiotics in Mycobacterium tuberculosis. Eis from M. tuberculosis (Eis_Mtb) and from M. smegmatis (Eis_Msm) both function as acetyltransferases capable of acetylating multiple amines of many AGs; however, these Eis homologs differ in AG substrate preference and number of acetylated amine groups per AG. The AG binding cavity of Eis_Mtb is divided into two narrow channels, whereas Eis_Msm contains one large cavity. Five bulky residues lining one of the AG binding channels of Eis_Mtb, His119, Ile268, Trp289, Gln291, and Glu401, have significantly smaller counterparts in Eis_Msm, Thr119, Gly266, Ala287, Ala289, and Gly401, respectively. To identify the residue(s) responsible for AG binding in Eis_Mtb and functional differences from Eis_Msm, we have generated single, double, triple, quadruple, and quintuple mutants of these residues in Eis_Mtb into their Eis_Msm counterparts and tested their acetylation activity with three structurally diverse AGs: kanamycin A (KAN), paromomyin (PAR), and apramycin (APR). We show that the penultimate C-terminal residue Glu401 plays a critical role in the overall activity of Eis_Mtb. We also demonstrate that the identities of residues Ile268, Trp289, and Gln291 (in Eis_Mtb nomenclature) dictate the differences between acetylation efficiencies of Eis_Mtb and Eis_Msm for KAN and PAR. Finally, we show that the mutation of Trp289 in Eis_Mtb into Ala plays a role in APR acetylation. PMID:23837529

  1. Supplement Analysis for the Wildlife Mitigation Program EIS (DOE/EIS-0246/SA-36)

    SciTech Connect

    N /A

    2003-10-10

    The compliance checklist for this project was originally completed by the Burns Paiute Tribe in 2000, and meets the standards and guidelines for the Wildlife Mitigation Program Environmental Impact Statement (EIS) and Record of Decision (ROD), as well as the Watershed Management Program Environmental Impact Statement (EIS) and Record of Decision (ROD). The Logan Valley Wildlife Mitigation Plan, now being implemented, continues to be consistent with the above mentioned EISs and RODs. Pursuant to its obligations under the Endangered Species Act, BPA has made a determination of whether its proposed project will have any effects on any listed species under the jurisdiction of the United States Fish and Wildlife Service (USFWS). A species list was obtained from USFWS on June 12, 2003, identifying bald eagles, Canada lynx, and bull trout as potentially occurring in the project area. A site assessment was conducted on July 15, 2003 to determine if these species were present and the potential effects of project activities. A ''No Effect'' determination was made for all ESA-listed species. There were no listed species under the jurisdiction of NOAA Fisheries present in the project area. As management activities proceed in the future, BPA will annually re-assess potential effects of planned activities on listed species. The Burns-Paiute Tribe conducted a literature search for historic and archaeological sites on the property on January 11, 1999. No known sites were identified. Further site-specific surveys will be conducted for individual ground disturbing activities. The results of these surveys will be sent to the Oregon State Historic Preservation Office and BPA. BPA will annually summarize and submit a report to the State Historic Preservation Office. On December 29, 1999, Fred Walasavage of BPA completed a Phase I Site Assessment and concluded that the site did not reveal any environmental factors that would pose a significant liability for remedial action or cleanup

  2. 14 CFR 1216.306 - Actions normally requiring an EIS.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... a space flight project/program which would return samples to Earth from solar system bodies (such as... an EIS include: (1) Development and operation of new launch vehicles or space transportation systems... nuclear reactor or radioisotope power systems and devices using a total quantity of radioactive material...

  3. Emotional intelligence (EI) and nursing leadership styles among nurse managers.

    PubMed

    Tyczkowski, Brenda; Vandenhouten, Christine; Reilly, Janet; Bansal, Gaurav; Kubsch, Sylvia M; Jakkola, Raelynn

    2015-01-01

    Less than 12.5% of nurses aspire to leadership roles, noting lack of support and stress as major factors in their decision not to pursue this area of practice. Psychological resiliency, described as the ability to properly adapt to stress and adversity, is key to successful nurse managers. Emotional intelligence (EI) is a related concept to resiliency and is another noteworthy predictor of leadership and management success. This study was undertaken to determine the level of and relationship between EI and leadership style of nurse managers employed in Wisconsin and Illinois facilities. A descriptive, exploratory study design was utilized, with a convenience sample of nurse managers working in 6 large Midwestern health systems. Nurse managers were invited to participate in the study by their employer, completing the online consent form and the demographic, Multifactor Leadership Questionnaire (MLQ) Form 5X and the Emotional Quotient Inventory (EQ-i 2.0) surveys. Statistically significant positive relationships were noted between EI and transformational leadership and the outcomes of leadership (extra effort, effectiveness, and satisfaction). No statistically significant relationships were noted between EI and transactional or laissez-faire leadership styles.

  4. 36 CFR 907.9 - Preparation of an EIS.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... ENVIRONMENTAL QUALITY § 907.9 Preparation of an EIS. (a) Notice of intent. When PADC decides to prepare an environmental impact statement, it shall publish a notice of intent in the Federal Register in accordance with... environmental impact statement will be prepared and publishing the notice of intent, PADC will begin to prepare...

  5. 36 CFR § 907.9 - Preparation of an EIS.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... ENVIRONMENTAL QUALITY § 907.9 Preparation of an EIS. (a) Notice of intent. When PADC decides to prepare an environmental impact statement, it shall publish a notice of intent in the Federal Register in accordance with... environmental impact statement will be prepared and publishing the notice of intent, PADC will begin to prepare...

  6. 36 CFR 907.7 - Determination of requirement for EIS.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... CORPORATION ENVIRONMENTAL QUALITY § 907.7 Determination of requirement for EIS. Determining whether to prepare an environmental impact statement is the first step in applying the NEPA process. In deciding whether to prepare an environmental impact statement, the responsible Corporation official will determine...

  7. 36 CFR 907.9 - Preparation of an EIS.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... ENVIRONMENTAL QUALITY § 907.9 Preparation of an EIS. (a) Notice of intent. When PADC decides to prepare an environmental impact statement, it shall publish a notice of intent in the Federal Register in accordance with... environmental impact statement will be prepared and publishing the notice of intent, PADC will begin to prepare...

  8. 36 CFR 907.7 - Determination of requirement for EIS.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... CORPORATION ENVIRONMENTAL QUALITY § 907.7 Determination of requirement for EIS. Determining whether to prepare an environmental impact statement is the first step in applying the NEPA process. In deciding whether to prepare an environmental impact statement, the responsible Corporation official will determine...

  9. Forestry Herbicide Environmental Risks--An EIS Perspective

    Treesearch

    D.G. Neary

    1989-01-01

    The U.S. Forest Service is in the process of completing Environmental Impact Statements (EIS's) on vegetation management for three physiographic regions of the South. This includes all forestry activities involving manipulation of plants in national forests and grasslands of the Coastal Plain-Piedmont, Appalachian Mountains, and the Ozark/Ouachita Mountains. These...

  10. 33 CFR 230.6 - Actions normally requiring an EIS.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Actions normally requiring an EIS. 230.6 Section 230.6 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY... consider the use of an environmental assessment (EA) on these types of actions if early studies and...

  11. 33 CFR 230.6 - Actions normally requiring an EIS.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Actions normally requiring an EIS. 230.6 Section 230.6 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY... consider the use of an environmental assessment (EA) on these types of actions if early studies and...

  12. 33 CFR 230.6 - Actions normally requiring an EIS.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... normally requiring an EIS are: (a) Feasibility reports for authorization and construction of major projects... consider the use of an environmental assessment (EA) on these types of actions if early studies and coordination show that a particular action is not likely to have a significant impact on the quality of the...

  13. 33 CFR 230.6 - Actions normally requiring an EIS.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... normally requiring an EIS are: (a) Feasibility reports for authorization and construction of major projects... consider the use of an environmental assessment (EA) on these types of actions if early studies and coordination show that a particular action is not likely to have a significant impact on the quality of the...

  14. What Can OpenEI Do For You?

    SciTech Connect

    2011-01-01

    Open Energy Information (OpenEI) is an open source web platform—similar to the one used by Wikipedia—developed by the US Department of Energy (DOE) and the National Renewable Energy Laboratory (NREL) to make the large amounts of energy-related data and information more easily searched, accessed, and used both by people and automated machine processes. Built utilizing the standards and practices of the Linked Open Data community, the OpenEI platform is much more robust and powerful than typical web sites and databases. As an open platform, all users can search, edit, add, and access data in OpenEI for free. The user community contributes the content and ensures its accuracy and relevance; as the community expands, so does the content's comprehensiveness and quality. The data are structured and tagged with descriptors to enable cross-linking among related data sets, advanced search functionality, and consistent, usable formatting. Data input protocols and quality standards help ensure the content is structured and described properly and derived from a credible source. Although DOE/NREL is developing OpenEI and seeding it with initial data, it is designed to become a true community model with millions of users, a large core of active contributors, and numerous sponsors.

  15. 43 CFR 10010.60 - Actions normally requiring an EIS.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... EIS: (1) Establishment of major new refuges or wildlife management areas, fish hatcheries, and major additions to such installations. (2) Master development and/or management plans for major new installations. (3) Management plans for established installations where major new developments or...

  16. 43 CFR 10010.60 - Actions normally requiring an EIS.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... EIS: (1) Establishment of major new refuges or wildlife management areas, fish hatcheries, and major additions to such installations. (2) Master development and/or management plans for major new installations. (3) Management plans for established installations where major new developments or...

  17. 43 CFR 10010.60 - Actions normally requiring an EIS.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... EIS: (1) Establishment of major new refuges or wildlife management areas, fish hatcheries, and major additions to such installations. (2) Master development and/or management plans for major new installations. (3) Management plans for established installations where major new developments or...

  18. 43 CFR 10010.60 - Actions normally requiring an EIS.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... EIS: (1) Establishment of major new refuges or wildlife management areas, fish hatcheries, and major additions to such installations. (2) Master development and/or management plans for major new installations. (3) Management plans for established installations where major new developments or...

  19. 7 CFR 1794.25 - Proposals normally requiring an EIS.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... (nameplate rating) other than fuel cell, combustion turbine, combined cycle, or diesel generators. All new... 1794.25 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE... EIS. The environmental review process, as described in this part, shall be used to identify those...

  20. 7 CFR 1794.25 - Proposals normally requiring an EIS.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... (nameplate rating) other than fuel cell, combustion turbine, combined cycle, or diesel generators. All new... 1794.25 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE... EIS. The environmental review process, as described in this part, shall be used to identify those...

  1. 7 CFR 1940.321 - Use of completed EIS.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... final EIS will be a major factor in the Agency's final decision. Agency staff making recommendations on... Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE...

  2. 32 CFR 651.42 - Actions normally requiring an EIS.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 4 2013-07-01 2013-07-01 false Actions normally requiring an EIS. 651.42 Section 651.42 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) ENVIRONMENTAL QUALITY ENVIRONMENTAL ANALYSIS OF ARMY ACTIONS (AR 200-2) Environmental Impact Statement § 651.42...

  3. 32 CFR 651.41 - Conditions requiring an EIS.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 4 2012-07-01 2011-07-01 true Conditions requiring an EIS. 651.41 Section 651.41 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) ENVIRONMENTAL QUALITY ENVIRONMENTAL ANALYSIS OF ARMY ACTIONS (AR 200-2) Environmental Impact Statement § 651.41...

  4. 32 CFR 651.42 - Actions normally requiring an EIS.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 4 2012-07-01 2011-07-01 true Actions normally requiring an EIS. 651.42 Section 651.42 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) ENVIRONMENTAL QUALITY ENVIRONMENTAL ANALYSIS OF ARMY ACTIONS (AR 200-2) Environmental Impact Statement § 651.42...

  5. 32 CFR 651.41 - Conditions requiring an EIS.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 4 2013-07-01 2013-07-01 false Conditions requiring an EIS. 651.41 Section 651.41 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) ENVIRONMENTAL QUALITY ENVIRONMENTAL ANALYSIS OF ARMY ACTIONS (AR 200-2) Environmental Impact Statement § 651.41...

  6. 32 CFR 651.41 - Conditions requiring an EIS.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 4 2014-07-01 2013-07-01 true Conditions requiring an EIS. 651.41 Section 651.41 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) ENVIRONMENTAL QUALITY ENVIRONMENTAL ANALYSIS OF ARMY ACTIONS (AR 200-2) Environmental Impact Statement § 651.41...

  7. 32 CFR 651.42 - Actions normally requiring an EIS.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 4 2014-07-01 2013-07-01 true Actions normally requiring an EIS. 651.42 Section 651.42 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) ENVIRONMENTAL QUALITY ENVIRONMENTAL ANALYSIS OF ARMY ACTIONS (AR 200-2) Environmental Impact Statement § 651.42...

  8. 12 CFR 1815.109 - Preparation of an EIS.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Preparation of an EIS. 1815.109 Section 1815.109 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY... prepared, it shall publish a notice of intent in the Federal Register in accordance with 40 CFR 1501.7 and...

  9. What Can OpenEI Do For You?

    ScienceCinema

    None

    2016-07-12

    Open Energy Information (OpenEI) is an open source web platform—similar to the one used by Wikipedia—developed by the US Department of Energy (DOE) and the National Renewable Energy Laboratory (NREL) to make the large amounts of energy-related data and information more easily searched, accessed, and used both by people and automated machine processes. Built utilizing the standards and practices of the Linked Open Data community, the OpenEI platform is much more robust and powerful than typical web sites and databases. As an open platform, all users can search, edit, add, and access data in OpenEI for free. The user community contributes the content and ensures its accuracy and relevance; as the community expands, so does the content's comprehensiveness and quality. The data are structured and tagged with descriptors to enable cross-linking among related data sets, advanced search functionality, and consistent, usable formatting. Data input protocols and quality standards help ensure the content is structured and described properly and derived from a credible source. Although DOE/NREL is developing OpenEI and seeding it with initial data, it is designed to become a true community model with millions of users, a large core of active contributors, and numerous sponsors.

  10. 32 CFR 651.42 - Actions normally requiring an EIS.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Actions normally requiring an EIS. 651.42 Section 651.42 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) ENVIRONMENTAL QUALITY ENVIRONMENTAL ANALYSIS OF ARMY ACTIONS (AR 200-2) Environmental Impact Statement §...

  11. 78 FR 15039 - Extending Scoping Period To Prepare a Programmatic Environmental Impact Statement (EIS) for the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-08

    ... Statement (EIS) for the Navajo Nation Integrated Weed Management Plan Within Coconino, Navajo, and Apache... the public scoping period to prepare an EIS for the Navajo Nation Integrated Weed Management Plan...

  12. Supplement Analysis for the Wildlife Mitigation Program EIS (DOE/EIS-0246/SA-18)

    SciTech Connect

    N /A

    2001-10-17

    BPA proposes to fund the acquisition and preservation of approximately 99 acres of native wet prairie and oak woodland habitat in Lane County, Oregon. Title to the land will be held by The Nature Conservancy, who will convey permanent mitigation rights to BPA in the form of a conservation easement. These newly acquired parcels will become part of the existing 330-acre Willow Creek Wildlife Mitigation Area. Passive management practices may take place on the land until a wildlife mitigation and management plan is developed and approved for the property. The compliance checklist for this project was completed by Cathy MacDonald with The Nature Conservancy and meets the standards and guidelines for the Wildlife Mitigation Program Environmental Impact Statement (EIS) and Record of Decision (ROD). A comprehensive wildlife mitigation and management plan will be prepared for the property after it is acquired and will follow the guidelines and mitigation measures detailed in the Wildlife Mitigation Program EIS and ROD. No plant or animal species listed under the Endangered Species Act (ESA) will be affected by the proposed acquisition of the subject property. Through contact with the U.S. Fish and Wildlife Service, the National Marine Fisheries Service, and the Oregon Natural Heritage Program, staff from The Nature Conservancy identified a number of federal and state listed species that have the potential to occur at the project site. ESA Section 7 consultation will be conducted by BPA and The Nature Conservancy, as necessary, prior to the implementation of any restoration or enhancement activities on the site. A cultural resource survey was conducted at the Eugene Wetlands Phase II site on July 9, 2001. No prehistoric or historic cultural materials were observed during the survey and no landforms considered likely to be archaeological sites were noted. The nearest recorded archeological find consists of two prehistoric sites that are located within a mile of the project

  13. Supplement Analysis for the Wildlife Management Program EIS (DOE/EIS-0246/SA-17)

    SciTech Connect

    N /A

    2001-09-13

    BPA proposes to partially fund the acquisition of 7,630 acres of shrub-steppe, riparian, and wetland habitat in northern Franklin County, Washington. Title to the land will be transferred initially to The Conservation Fund and ultimately for inclusion as part of the National Wildlife Refuge System. Passive management practices will take place on the land until an official management plan is developed and approved for the property. Some short-term control of invasive, exotic plant species may occur as necessary prior to the approval of a management plan. The compliance checklist for this project was completed by Randy Hill with the U.S. Fish and Wildlife Service, Columbia National Wildlife Refuge and meets the standards and guidelines for the Wildlife Mitigation Program Environmental Impact Statement (EIS) and Record of Decision (ROD). A comprehensive management plan will be prepared for the property after it is acquired and will follow the guidelines and mitigation measures detailed in the Wildlife Mitigation Program EIS and ROD. No plant or animal species listed under the Endangered Species Act (ESA) will be affected by the fee-title purchase of the subject property. Mark Miller with the Eastern Washington Ecological Services Office of USFWS concurred with this finding on August 3, 2001. Section 7 consultation will be conducted by BPA and USFWS, as necessary, prior to the implementation of any restoration or enhancement activities on the site. In accordance with the National Historic Preservation Act of 1966 (NHPA) and USFWS policy, the addition of the Eagle Lakes property to the National Wildlife Refuge System does not constitute an undertaking as defined by the NHPA, or require compliance with Section 106 of the NHPA. Anan Raymond, Regional Archaeologist with USFWS Region 1 Cultural Resource Team, concurred with this finding on May 4, 2001. Compliance with NHPA, including cultural resources surveys, will be implemented, as necessary, once specific management

  14. 36 CFR 1010.6 - Determination of requirement for EA or EIS.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... for EA or EIS. 1010.6 Section 1010.6 Parks, Forests, and Public Property PRESIDIO TRUST ENVIRONMENTAL QUALITY § 1010.6 Determination of requirement for EA or EIS. In deciding whether to require the preparation of an EA or an EIS, the NEPA Compliance Coordinator will determine whether the proposal is...

  15. An Improved Procedure for EI Nino Forecasting: Implications for Predictability.

    PubMed

    Chen, D; Zebiak, S E; Busalacchi, A J; Cane, M A

    1995-09-22

    A coupled ocean-atmosphere data assimilation procedure yields improved forecasts of El Niño for the 1980s compared with previous forecasting procedures. As in earlier forecasts with the same model, no oceanic data were used, and only wind information was assimilated. The improvement is attributed to the explicit consideration of air-sea interaction in the initialization. These results suggest that EI Niño is more predictable than previously estimated, but that predictability may vary on decadal or longer time scales. This procedure also eliminates the well-known spring barrier to EI Niño prediction, which implies that it may not be intrinsic to the real climate system.

  16. DARHT - an `adequate` EIS: A NEPA case study

    SciTech Connect

    Webb, M.D.

    1997-08-01

    The Dual Axis Radiographic Hydrodynamic Test (DARHT) Facility Environmental Impact Statement (EIS) provides a case study that is interesting for many reasons. The EIS was prepared quickly, in the face of a lawsuit, for a project with unforeseen environmental impacts, for a facility that was deemed urgently essential to national security. Following judicial review the EIS was deemed to be {open_quotes}adequate.{close_quotes} DARHT is a facility now being built at Los Alamos National Laboratory (LANL) as part of the Department of Energy (DOE) nuclear weapons stockpile stewardship program. DARHT will be used to evaluate the safety and reliability of nuclear weapons, evaluate conventional munitions and study high-velocity impact phenomena. DARHT will be equipped with two accelerator-driven, high-intensity X-ray machines to record images of materials driven by high explosives. DARHT will be used for a variety of hydrodynamic tests, and DOE plans to conduct some dynamic experiments using plutonium at DARHT as well.

  17. Sulfonamide-Based Inhibitors of Aminoglycoside Acetyltransferase Eis Abolish Resistance to Kanamycin in Mycobacterium tuberculosis.

    PubMed

    Garzan, Atefeh; Willby, Melisa J; Green, Keith D; Gajadeera, Chathurada S; Hou, Caixia; Tsodikov, Oleg V; Posey, James E; Garneau-Tsodikova, Sylvie

    2016-12-08

    A two-drug combination therapy where one drug targets an offending cell and the other targets a resistance mechanism to the first drug is a time-tested, yet underexploited approach to combat or prevent drug resistance. By high-throughput screening, we identified a sulfonamide scaffold that served as a pharmacophore to generate inhibitors of Mycobacterium tuberculosis acetyltransferase Eis, whose upregulation causes resistance to the aminoglycoside (AG) antibiotic kanamycin A (KAN) in Mycobacterium tuberculosis. Rational systematic derivatization of this scaffold to maximize Eis inhibition and abolish the Eis-mediated KAN resistance of M. tuberculosis yielded several highly potent agents. A crystal structure of Eis in complex with one of the most potent inhibitors revealed that the inhibitor bound Eis in the AG-binding pocket held by a conformationally malleable region of Eis (residues 28-37) bearing key hydrophobic residues. These Eis inhibitors are promising leads for preclinical development of innovative AG combination therapies against resistant TB.

  18. Clinical consequences of the EI/MCS "diagnosis": two paths.

    PubMed

    Staudenmayer, H

    1996-08-01

    There are two distinct paths down which patients "diagnosed" with environmental illness/multiple chemical sensitivities (EI/MCS) can travel. Along the first path, beliefs about low-level, multiple chemical sensitivities as the cause of physical and psychological symptoms are instilled and reinforced by a host of factors including toxicogenic speculation, iatrogenic influence mediated by unsubstantiated diagnostic and treatment practices, patient support/advocacy networks, and social contagion. Intrapsychic factors also reinforce this path through the motivational mechanism of factitious malingering, or unconscious primary and secondary gain, mediated through psychological defenses, particularly projection of cause of illness onto the physical environment. The second path involves restructuring distorted beliefs about chemical sensitivities. Explanations of the placebo effect, the physiology of the stress response, and the symptoms of anxiety and panic facilitate the direction of EI/MCS patients onto this path. A decision model is presented to discriminate among toxicogenic and psychogenic explanations of the EI/MCS phenomenon, based on appraisal of reaction and physiologic and cognitive responses during provocation chamber challenges under double-blind, placebo-controlled conditions. These studies have been helpful therapeutically for some patients in selecting the path that leads to wellness. This paper suggests how various therapeutic techniques can be employed with difficult patients. Often, supportive psychotherapy establishes a therapeutic alliance which facilitates cognitive therapy to restructure distorted beliefs. In the process of finding alternative explanations to chemical sensitivities, the etiology of symptoms is related to stressful life events, including childhood experiences which may have disrupted normal personality development and coping capacity. Furthermore, biological and physiological sequelae stemming from early, chronic trauma have been

  19. Biochemical and Structural Analysis of an Eis Family Aminoglycoside Acetyltransferase from Bacillus anthracis

    SciTech Connect

    Green, Keith D.; Biswas, Tapan; Chang, Changsoo; Wu, Ruiying; Chen, Wenjing; Janes, Brian K.; Chalupska, Dominika; Gornicki, Piotr; Hanna, Philip C.; Tsodikov, Oleg V.; Joachimiak, Andrzej; Garneau-Tsodikova, Sylvie

    2015-05-26

    Proteins from the enhanced intracellular survival (Eis) family are versatile acetyltransferases that acetylate amines at multiple positions of several aminoglycosides (AGs). Their upregulation confers drug resistance. Homologues of Eis are present in diverse bacteria, including many pathogens. Eis from Mycobacterium tuberculosis (Eis_Mtb) has been well characterized. In this study, we explored the AG specificity and catalytic efficiency of the Eis family protein from Bacillus anthracis (Eis_Ban). Kinetic analysis of specificity and catalytic efficiency of acetylation of six AGs indicates that Eis_Ban displays significant differences from Eis_Mtb in both substrate binding and catalytic efficiency. The number of acetylated amines was also different for several AGs, indicating a distinct regiospecificity of Eis_Ban. Furthermore, most recently identified inhibitors of Eis_Mtb did not inhibit Eis_Ban, underscoring the differences between these two enzymes. To explain these differences, we determined an Eis_Ban crystal structure. The comparison of the crystal structures of Eis_Ban and Eis_Mtb demonstrates that critical residues lining their respective substrate binding pockets differ substantially, explaining their distinct specificities. Our results suggest that acetyltransferases of the Eis family evolved divergently to garner distinct specificities while conserving catalytic efficiency, possibly to counter distinct chemical challenges. The unique specificity features of these enzymes can be utilized as tools for developing AGs with novel modifications and help guide specific AG treatments to avoid Eis-mediated resistance.

  20. Combating Enhanced Intracellular Survival (Eis)-Mediated Kanamycin Resistance of Mycobacterium tuberculosis by Novel Pyrrolo[1,5-a]pyrazine-Based Eis Inhibitors.

    PubMed

    Garzan, Atefeh; Willby, Melisa J; Ngo, Huy X; Gajadeera, Chathurada S; Green, Keith D; Holbrook, Selina Y L; Hou, Caixia; Posey, James E; Tsodikov, Oleg V; Garneau-Tsodikova, Sylvie

    2017-02-17

    Tuberculosis (TB) remains one of the leading causes of mortality worldwide. Hence, the identification of highly effective antitubercular drugs with novel modes of action is crucial. In this paper, we report the discovery and development of pyrrolo[1,5-a]pyrazine-based analogues as highly potent inhibitors of the Mycobacterium tuberculosis (Mtb) acetyltransferase enhanced intracellular survival (Eis), whose up-regulation causes clinically observed resistance to the aminoglycoside (AG) antibiotic kanamycin A (KAN). We performed a structure-activity relationship (SAR) study to optimize these compounds as potent Eis inhibitors both against purified enzyme and in mycobacterial cells. A crystal structure of Eis in complex with one of the most potent inhibitors reveals that the compound is bound to Eis in the AG binding pocket, serving as the structural basis for the SAR. These Eis inhibitors have no observed cytotoxicity to mammalian cells and are promising leads for the development of innovative AG adjuvant therapies against drug-resistant TB.

  1. Hinode/EIS plasma diagnostics in the flaring solar chromosphere

    NASA Astrophysics Data System (ADS)

    Graham, D. R.; Fletcher, L.; Hannah, I. G.

    2011-08-01

    Context. The impulsive phase of solar flares is a time of rapid energy deposition and heating in the lower solar atmosphere, leading to changes in the temperature, density, ionisation and velocity structure of this region. Aims: We aim to study the lower atmosphere during the impulsive phase of a flare using imaging and spectroscopic data from Hinode/EIS, RHESSI and TRACE. We place these observations in context by using a wide range of temperature observations from each instrument. Methods: We analyse sparse raster data from the Hinode/EIS spectrometer to derive the density and line-of-sight velocity in flare footpoints, in a GOES C6.6 flare observed on 05-June-2007. The raster duration was 150s across the centre of a small active region, allowing multiple exposures of the flare ribbons and footpoints. Using RHESSI and Hinode/XRT we test both non-thermal and thermal models for the HXR emission. Results: During the flare impulsive phase, we find evidence from XRT for flare footpoints at temperatures exceeding 7 MK. We measure the electron number density increasing up to a few ×1010 cm-3 in the footpoints, at temperatures of ~1.5-2 MK, accompanied by small downflows at temperatures below Fe XIII and upflows of up to ~140 km s-1 at temperatures above. This is reasonable in the context of HXR diagnostics of the flare electron beam. The electrons inferred have sufficient energy to affect the chromospheric ionisation structure. Conclusions: EIS sparse raster data coupled with RHESSI imaging and spectroscopy prove useful here in studying the lower atmosphere of solar flares, and in this event suggest heat deposition relatively high in the chromosphere drives chromospheric evaporation while increasing the observed electron densities at footpoints. However, from RHESSI spectral fitting it is not possible to say whether the data are more consistent with a model including a non-thermal beam, or purely thermal model.

  2. Fan Loops Observed by IRIS, EIS, and AIA

    NASA Astrophysics Data System (ADS)

    Ghosh, Avyarthana; Tripathi, Durgesh; Gupta, G. R.; Polito, Vanessa; Mason, Helen E.; Solanki, Sami K.

    2017-02-01

    A comprehensive study of the physical parameters of active region fan loops is presented using the observations recorded with the Interface Region Imaging Spectrometer (IRIS), the EUV Imaging Spectrometer (EIS) on board Hinode, and the Atmospheric Imaging Assembly (AIA) and the Helioseismic and Magnetic Imager (HMI) on board the Solar Dynamics Observatory (SDO). The fan loops emerging from non-flaring AR 11899 (near the disk center) on 2013 November 19 are clearly discernible in AIA 171 Å images and in those obtained in Fe viii and Si vii images using EIS. Our measurements of electron densities reveal that the footpoints of these loops are at an approximately constant pressure with electron densities of {log} {N}e=10.1 cm‑3 at {log} [T/K]=5.15 (O iv), and {log} {N}e=8.9 cm‑3 at {log} [T/K]=6.15 (Si x). The electron temperature diagnosed across the fan loops by means of EM-Loci suggest that two temperature components exist at {log} [T/K]=4.95 and 5.95 at the footpoints. These components are picked up by IRIS lines and EIS lines, respectively. At higher heights, the loops are nearly isothermal at {log} [T/K]=5.95, which remained constant along the loop. The measurement of the Doppler shift using IRIS lines suggests that the plasma at the footpoints of these loops is predominantly redshifted by 2–3 km s‑1 in C ii, 10–15 km s‑1 in Si iv, and 15–20 km s‑1 in O iv, reflecting the increase in the speed of downflows with increasing temperature from {log} [T/K]=4.40 to 5.15. These observations can be explained by low-frequency nanoflares or impulsive heating, and provide further important constraints on the modeling of the dynamics of fan loops.

  3. Draft Executive Summary Hawaii Geothermal Project - EIS Scoping Meetings

    SciTech Connect

    1992-03-01

    After introductions by the facilitator and the program director from DOE, process questions were entertained. It was also sometimes necessary to make clarifications as to process throughout the meetings. Topics covered federal involvement in the HGP-EIS; NEPA compliance; public awareness, review, and access to information; Native Hawaiian concerns; the record of decision, responsibility with respect to international issues; the impacts of prior and on-going geothermal development activities; project definition; alternatives to the proposed action; necessary studies; Section 7 consultations; socioeconomic impacts; and risk analysis. Presentations followed, in ten meetings, 163 people presented issues and concerns, 1 additional person raised process questions only.

  4. Two concurrent EIS projects involving the same agencies

    SciTech Connect

    Thompson, M.G. ); Schaddel, T.L. . Div. of Aeronautics)

    1993-01-01

    In 1990-91 the US Air Force prepared environmental impact statements (EIS) for the disposal and reuse of Chanute Air Force Base in Rantoul, Illinois and for the joint military-civilian use of Scott Air Force Base in St. Clair County, Illinois. The Federal Aviation Administration, Chicago Airports District Office and the Illinois Department of Transportation, Division of Aeronautics were cooperating agencies for both projects. This paper summarizes the two environmental impact statements and analyzes the processes followed in preparing both documents.

  5. Retrospective evaluation of exposure index (EI) values from plain radiographs reveals important considerations for quality improvement

    SciTech Connect

    Mothiram, Ursula; Brennan, Patrick C; Robinson, John; Lewis, Sarah J; Moran, Bernadette

    2013-12-15

    Following X-ray exposure, radiographers receive immediate feedback on detector exposure in the form of the exposure index (EI). To identify whether radiographers are meeting manufacturer-recommended EI (MREI) ranges for routine chest, abdomen and pelvis X-ray examinations under a variety of conditions and to examine factors affecting the EI. Data on 5000 adult X-ray examinations including the following variables were collected: examination parameters, EI values, patient gender, date of birth, date and time of examination, grid usage and the presence of implant or prosthesis. Descriptive statistics were used to summarize each data set and the Mann–Whitney U test was used to determine significant differences, with P < 0.05 indicating significance for all tests. Most examinations demonstrated EI values that were outside the MREI ranges, with significantly higher median EI values recorded for female patient radiographs than those for male patients for all manufacturers, indicating higher detector exposures for all units except for Philips digital radiography (DR), where increased EI values indicate lower exposure (P = 0.01). Median EI values for out of hours radiography were also significantly higher compared with normal working hours for all technologies (P ≤ 0.02). Significantly higher median EI values were demonstrated for Philips DR chest X-rays without as compared to those with the employment of a grid (P = 0.03), while significantly lower median EI values were recorded for Carestream Health computed radiography (CR) chest X-rays when an implant or prosthesis was present (P = 0.02). Non-adherence to MREIs has been demonstrated with EI value discrepancies being dependent on patient gender, time/day of exposure, grid usage and the presence of an implant or prosthesis. Retrospective evaluation of EI databases is a valuable tool to assess the need of quality improvement in routine DR.

  6. Retrospective evaluation of exposure index (EI) values from plain radiographs reveals important considerations for quality improvement

    PubMed Central

    Mothiram, Ursula; Brennan, Patrick C; Robinson, John; Lewis, Sarah J; Moran, Bernadette

    2013-01-01

    Introduction Following X-ray exposure, radiographers receive immediate feedback on detector exposure in the form of the exposure index (EI). Purpose To identify whether radiographers are meeting manufacturer-recommended EI (MREI) ranges for routine chest, abdomen and pelvis X-ray examinations under a variety of conditions and to examine factors affecting the EI. Methods Data on 5000 adult X-ray examinations including the following variables were collected: examination parameters, EI values, patient gender, date of birth, date and time of examination, grid usage and the presence of implant or prosthesis. Descriptive statistics were used to summarize each data set and the Mann–Whitney U test was used to determine significant differences, with P < 0.05 indicating significance for all tests. Results Most examinations demonstrated EI values that were outside the MREI ranges, with significantly higher median EI values recorded for female patient radiographs than those for male patients for all manufacturers, indicating higher detector exposures for all units except for Philips digital radiography (DR), where increased EI values indicate lower exposure (P = 0.01). Median EI values for out of hours radiography were also significantly higher compared with normal working hours for all technologies (P ≤ 0.02). Significantly higher median EI values were demonstrated for Philips DR chest X-rays without as compared to those with the employment of a grid (P = 0.03), while significantly lower median EI values were recorded for Carestream Health computed radiography (CR) chest X-rays when an implant or prosthesis was present (P = 0.02). Conclusions Non-adherence to MREIs has been demonstrated with EI value discrepancies being dependent on patient gender, time/day of exposure, grid usage and the presence of an implant or prosthesis. Retrospective evaluation of EI databases is a valuable tool to assess the need of quality improvement in routine DR. PMID:26229619

  7. Monitoring solid phase synthesis reactions with electrochemical impedance spectroscopy (EIS).

    PubMed

    Hutton, Roger S; Adams, Joseph P; Trivedi, Harish S

    2003-01-01

    This work describes the use of electrochemical impedance spectroscopy (EIS) as a means to monitor solid phase synthesis on resin beads. EIS was used to track changes during the swelling of beads in various solvents, during three typical reactions and throughout cleavage of the final product from the bead. The impedance response was investigated in a chemical reactor and was found to be faintly sensitive to the resin swelling and solvent flow. The position of the electrode within the reactor was found to be critical as polystyrene based beads float or sink dependent upon the solvent used. However, by choosing electrode position it was possible to monitor reaction progress on beads or within the bulk reactant/product mixture. Of the three typical chemical reactions studied impedance spectroscopy successfully followed two. Fitting of the impedance data to an equivalent electrical circuit provided an estimate as to the relative contribution of capacitive and resistive components to the overall response. Kinetic data from two reactions were also modelled, in both cases complex kinetics was observed, in close agreement with other studies.

  8. Active Region Moss: Doppler Shifts from Hinode/EIS Observations

    NASA Technical Reports Server (NTRS)

    Tripathi, Durgesh; Mason, Helen E.; Klimchuk, James A.

    2012-01-01

    Studying the Doppler shifts and the temperature dependence of Doppler shifts in moss regions can help us understand the heating processes in the core of the active regions. In this paper we have used an active region observation recorded by the Extreme-ultraviolet Imaging Spectrometer (EIS) onboard Hinode on 12-Dec- 2007 to measure the Doppler shifts in the moss regions. We have distinguished the moss regions from the rest of the active region by defining a low density cut-off as derived by Tripathi et al. (2010). We have carried out a very careful analysis of the EIS wavelength calibration based on the method described in Young, O Dwyer and Mason (2012). For spectral lines having maximum sensitivity between log T = 5.85 and log T = 6.25 K, we find that the velocity distribution peaks at around 0 km/s with an estimated error of 4 km/s. The width of the distribution decreases with temperature. The mean of the distribution shows a blue shift which increases with increasing temperature and the distribution also shows asymmetries towards blue-shift. Comparing these results with observables predicted from different coronal heating models, we find that these results are consistent with both steady and impulsive heating scenarios. Further observational constraints are needed to distinguish between these two heating scenarios.

  9. Temperature and Density Analysis of a Coronal Loop Using EIS

    NASA Astrophysics Data System (ADS)

    Garst, J. W.; Schmelz, J. T.

    2008-05-01

    The temperature analysis of coronal loops has produced contradictory results. Image ratios from TRACE show substantially smaller temperature gradients than predicted by standard models for loops in hydrodynamic equilibrium. TRACE has state-of-the-art spatial resolution but limited temperature coverage. On the other hand, the pixels of the Coronal Diagnostics Spectrometer (CDS) on SOHO are larger but its temperature resolution is state-of-the-art. Loop results from differential emission measure analyses from CDS data have been questioned due to the resolving power. Loop analysis could benefit greatly from observations by an instrument with the spatial resolution of TRACE and the temperature coverage of CDS. A spectrometer with (almost) these characteristics was launched in September 2006 on the Japanese/USA/UK Hinode mission. The EUV Imaging Spectrometer (EIS) is similar to CDS, observing emission lines originating from the solar corona and upper transition region at wavelength intervals in the extreme ultraviolet, but with a spatial resolution that is almost as good as TRACE. Differential emission measure and density analysis is done on the coronal loop data observed by EIS on 01 June 2007. Results from CDS and TRACE analysis are compared and discussed qualitatively. Solar physics research at the University of Memphis is supported by a Hinode subcontract from NASA/SAO as well as NSF ATM-0402729.

  10. An EIS study of the corrosive behavior of propellant hydrazine

    SciTech Connect

    Bhardwaj, R.C.; Davis, D.D.; Baker, D.L.

    1996-11-01

    Corrosion behavior of iron (Fe), nickel (Ni), cobalt (Co) and titanium (Ti) alloys in hydrazine (N{sub 2}H{sub 4}) and CO{sub 2}-contaminated N{sub 2}H{sub 4} were studied using Electrochemical Impedance Spectroscopy (EIS). The corrosion rate of Fe and Ti alloys increased in hydrazine and CO{sub 2}-contaminated hydrazine as a function of time and CO{sub 2} concentration; however, the corrosion rate of Ni and Co alloy decreased as a function of time in contaminated hydrazine. The corrosion rate of Ni and Co alloys were significantly higher when compared with corrosion rates of Fe and Ti alloys in CO{sub 2}-contaminated hydrazine. The effects of CO{sub 2} concentration on corrosion rate has been explained in terms of alloy composition and the role of CO{sub 2} in forming carbazic acid and its metal complexes. The polarization values obtained from EIS studies were used to calculate the exchange current density and decomposition rate of hydrazine.

  11. Recommendations for an Executive Information System (EIS) for the NASA Accounting and Financial Information System (NAFIS)

    NASA Technical Reports Server (NTRS)

    Goss, Ernest Preston

    1991-01-01

    The objectives were to: (1) survey state-of-the-art computing architectures, tools, and technologies for implementing an Executive Information System (EIS); (2) review MSFC capabilities and efforts in developing an EIS for Shuttle Projects Office and the Payloads Project Office; (3) review management reporting requirements for the NASA Accounting and Financial Information System (NAFIS) Project in the areas of cost, schedule, and technical performance, and insure that the EIS fully supports these requirements; and (4) develop and implement a pilot concept for a NAFIS EIS. A summary of the findings of this work is presented.

  12. 75 FR 81709 - Mississippi Division; Rescinding the Notice of Intent for an Environmental Impact Statement (EIS...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-28

    ... Impact Statement (EIS): Harrison, George, Greene, Jackson, Perry, and Stone Counties, Mississippi AGENCY..., Harrison, George, Greene, Jackson, Perry, and Stone Counties, Mississippi. The original Notice of Intent...

  13. How enhanced molecular ions in Cold EI improve compound identification by the NIST library.

    PubMed

    Alon, Tal; Amirav, Aviv

    2015-12-15

    Library-based compound identification with electron ionization (EI) mass spectrometry (MS) is a well-established identification method which provides the names and structures of sample compounds up to the isomer level. The library (such as NIST) search algorithm compares different EI mass spectra in the library's database with the measured EI mass spectrum, assigning each of them a similarity score called 'Match' and an overall identification probability. Cold EI, electron ionization of vibrationally cold molecules in supersonic molecular beams, provides mass spectra with all the standard EI fragment ions combined with enhanced Molecular Ions and high-mass fragments. As a result, Cold EI mass spectra differ from those provided by standard EI and tend to yield lower matching scores. However, in most cases, library identification actually improves with Cold EI, as library identification probabilities for the correct library mass spectra increase, despite the lower matching factors. This research examined the way that enhanced molecular ion abundances affect library identification probability and the way that Cold EI mass spectra, which include enhanced molecular ions and high-mass fragment ions, typically improve library identification results. It involved several computer simulations, which incrementally modified the relative abundances of the various ions and analyzed the resulting mass spectra. The simulation results support previous measurements, showing that while enhanced molecular ion and high-mass fragment ions lower the matching factor of the correct library compound, the matching factors of the incorrect library candidates are lowered even more, resulting in a rise in the identification probability for the correct compound. This behavior which was previously observed by analyzing Cold EI mass spectra can be explained by the fact that high-mass ions, and especially the molecular ion, characterize a compound more than low-mass ions and therefore carries more

  14. A solar tornado observed by EIS. Plasma diagnostics

    NASA Astrophysics Data System (ADS)

    Levens, P. J.; Labrosse, N.; Fletcher, L.; Schmieder, B.

    2015-10-01

    Context. The term "solar tornadoes" has been used to describe apparently rotating magnetic structures above the solar limb, as seen in high resolution images and movies from the Atmospheric Imaging Assembly (AIA) aboard the Solar Dynamics Observatory (SDO). These often form part of the larger magnetic structure of a prominence, however the links between them remain unclear. Here we present plasma diagnostics on a tornado-like structure and its surroundings, seen above the limb by the Extreme-ultraviolet Imaging Spectrometer (EIS) aboard the Hinode satellite. Aims: We aim to extend our view of the velocity patterns seen in tornado-like structures with EIS to a wider range of temperatures and to use density diagnostics, non-thermal line widths, and differential emission measures to provide insight into the physical characteristics of the plasma. Methods: Using Gaussian fitting to fit and de-blend the spectral lines seen by EIS, we calculated line-of-sight velocities and non-thermal line widths. Along with information from the CHIANTI database, we used line intensity ratios to calculate electron densities at each pixel. Using a regularised inversion code we also calculated the differential emission measure (DEM) at different locations in the prominence. Results: The split Doppler-shift pattern is found to be visible down to a temperature of around log T = 6.0. At temperatures lower than this, the pattern is unclear in this data set. We obtain an electron density of log ne = 8.5 when looking towards the centre of the tornado structure at a plasma temperature of log T = 6.2, as compared to the surroundings of the tornado structure where we find log ne to be nearer 9. Non-thermal line widths show broader profiles at the tornado location when compared to the surrounding corona. We discuss the differential emission measure in both the tornado and the prominence body, which suggests that there is more contribution in the tornado at temperatures below log T = 6.0 than in the

  15. 1992 Columbia River Salmon Flow Measures Options Analysis/EIS.

    SciTech Connect

    Not Available

    1992-01-01

    This Options Analysis/Environmental Impact Statement (OA/EIS) identifies, presents effects of, and evaluates the potential options for changing instream flow levels in efforts to increase salmon populations in the lower Columbia and Snake rivers. The potential actions would be implemented during 1992 to benefit juvenile and adult salmon during migration through eight run-of-river reservoirs. The Corps of Engineers (Corps) prepared this document in cooperation with the Bonneville Power Administration and the Bureau of Reclamation. The US Fish and Wildlife Service (FSWS) is a participating agency. The text and appendices of the document describe the characteristics of 10 Federal projects and one private water development project in the Columbia River drainage basin. Present and potential operation of these projects and their effects on the salmon that spawn and rear in the Columbia and Snake River System are presented. The life history, status, and response of Pacific salmon to current environmental conditions are described.

  16. Hinode/EIS science planning and operations tools

    NASA Astrophysics Data System (ADS)

    Rainnie, Jonn A.

    2016-07-01

    We present the design, implementation and maintenance of the suite of software enabling scientists to design and schedule Hinode/EIS1 operations. The total of this software is the EIS Science Planning Tools (EISPT), and is predominately written in IDL (Interactive Data Language), coupled with SolarSoft (SSW), an IDL library developed for solar missions. Hinode is a multi-instrument and wavelength mission designed to observe the Sun. It is a joint Japan/UK/US consortium (with ESA and Norwegian involvement). Launched in September 2006, its principal scientific goals are to study the Sun's variability and the causes of solar activity. Hinode operations are coordinated at ISAS (Tokyo, Japan). A daily Science Operations meeting is attended by the instrument teams and the spacecraft team. Nominally, science plan uploads cover periods of two or three days. When the forthcoming operations have been agreed, the necessary spacecraft operations parameters are created. These include scheduling for spacecraft pointing and ground stations. The Extreme UV Imaging Spectrometer (EIS) instrument, led by the UK (the PI institute is MSSL), is designed to observe the emission spectral lines of the solar atmosphere. Observations are composed of reusable, hierarchical components, including lines lists (wavelengths of spectral lines), rasters (exposure times, line list, etc.) and studies (defines one or more rasters). Studies are the basic unit of "timeline" scheduling. They are a useful construct for generating more complex sequences of observations, reducing the planning burden. Instrument observations must first be validated. An initial requirement was that operations be shared equally by the 3 main EIS teams (Japan, UK and US). Hence, a major design focus of the software was "Remote Operations", whereby any scientist in any location can run the software, schedule a science plan and send it to the spacecraft commanding team. It would then be validated and combined with the science

  17. Interchange of electronic design through VHDL and EIS

    NASA Technical Reports Server (NTRS)

    Wallace, Richard M.

    1987-01-01

    The need for both robust and unambiguous electronic designs is a direct requirement of the astonishing growth in design and manufacturing capability during recent years. In order to manage the plethora of designs, and have the design data both interchangeable and interoperable, the Very High Speed Integrated Circuits (VHSIC) program is developing two major standards for the electronic design community. The VHSIC Hardware Description Language (VHDL) is designed to be the lingua franca for transmission of design data between designers and their environments. The Engineering Information System (EIS) is designed to ease the integration of data betweeen diverse design automation systems. This paper describes the rationale for the necessity for these two standards and how they provide a synergistic expressive capability across the macrocosm of design environments.

  18. A CMOS Electrochemical Impedance Spectroscopy (EIS) Biosensor Array.

    PubMed

    Manickam, Arun; Chevalier, Aaron; McDermott, Mark; Ellington, Andrew D; Hassibi, Arjang

    2010-12-01

    In this paper, we present a fully integrated biosensor 10 × 10 array in a standard complementary metal-oxide semiconducor process, which takes advantage of electrochemical impedance spectroscopy (EIS). We also show that this system is able to detect various biological analytes, such as DNA and proteins, in real time and without the need for molecular labels. In each pixel of this array, we implement a biocompatible Au electrode transducer and embedded sensor circuitry which takes advantage of the coherent detector to measure the impedance of the associated electrode-electrolyte interface. This chip is capable of concurrently measuring admittance values as small as 10(-8) Ω(-1) within the array with the detection dynamic range of more than 90 dB in the frequency range of 10 Hz-50 MHz.

  19. Interchange of electronic design through VHDL and EIS

    NASA Astrophysics Data System (ADS)

    Wallace, Richard M.

    1987-10-01

    The need for both robust and unambiguous electronic designs is a direct requirement of the astonishing growth in design and manufacturing capability during recent years. In order to manage the plethora of designs, and have the design data both interchangeable and interoperable, the Very High Speed Integrated Circuits (VHSIC) program is developing two major standards for the electronic design community. The VHSIC Hardware Description Language (VHDL) is designed to be the lingua franca for transmission of design data between designers and their environments. The Engineering Information System (EIS) is designed to ease the integration of data betweeen diverse design automation systems. This paper describes the rationale for the necessity for these two standards and how they provide a synergistic expressive capability across the macrocosm of design environments.

  20. Velocity Characteristics of Evaporated Plasma using Hinode/EIS

    NASA Technical Reports Server (NTRS)

    Milligan, Ryan O.; Dennis, Brian R.

    2009-01-01

    This paper presents a detailed study of chromospheric evaporation using the EUV Imaging Spectrometer (EIS) onboard Hinode in conjunction with HXR observat,ions from RHESSI. The advanced capabilities of EIS were used to measure Doppler shifts in 15 emission lines covering the temperature range T=0.05-16 MK during the impulsive phase of a C-class flare on 2007 December 14. Blueshifts indicative of the evaporated material were observed in six emission lines from Fe XIV-XXIV (2-16 MK). Upflow velocity was found to scale with temperature as v(sub up) (kilometers per second) approximately equal to 5-17 T (MK). Although the hottest emission lines, Fe XXIII and Fe XXIV, exhibited upflows of greater than 200 kilometers per second, their line profiles were found to be dominated by a stationary component in stark contrast to the predictions of the standard flare model. Emission from O VI-Fe XIII lines (0.5-1.5 MK) was found to be redshifted by v(sub down) (kilometers per second) approximately equal to 60-17 T (MK) and was interpreted as the downward-moving 'plug' characteristic of explosive evaporation. These downflows occur at temperatures significantly higher than previously expected. Both upflows and downflows were spatially and temporally correlated with HXR emission observed by RHESSI that provided the properties of the electron beam deemed to be the driver of the evaporation. The energy contained in the electron beam was found to be greater than or equal to 10(sup 11) ergs per square centimeter per second consistent with the value required to drive explosive chromospheric evaporation from hydrodynamic simulations.

  1. Geothermal Exploration Case Studies on OpenEI (Presentation)

    SciTech Connect

    Young, K.; Bennett, M.; Atkins, D.

    2014-03-01

    The U.S. Geological Survey (USGS) resource assessment (Williams et al., 2008) outlined a mean 30 GWe of undiscovered hydrothermal resource in the western United States. One goal of the U.S. Department of Energy's (DOE) Geothermal Technology Office (GTO) is to accelerate the development of this undiscovered resource. DOE has focused efforts on helping industry identify hidden geothermal resources to increase geothermal capacity in the near term. Increased exploration activity will produce more prospects, more discoveries, and more readily developable resources. Detailed exploration case studies akin to those found in oil and gas (e.g. Beaumont and Foster, 1990-1992) will give developers central location for information gives models for identifying new geothermal areas, and guide efficient exploration and development of these areas. To support this effort, the National Renewable Energy Laboratory (NREL) has been working with GTO to develop a template for geothermal case studies on the Geothermal Gateway on OpenEI. In 2012, the template was developed and tested with two case studies: Raft River Geothermal Area (http://en.openei.org/wiki/Raft_River_Geothermal_Area) and Coso Geothermal Area (http://en.openei.org/wiki/Coso_Geothermal_Area). In 2013, ten additional case studies were completed, and Semantic MediaWiki features were developed to allow for more data and the direct citations of these data. These case studies are now in the process of external peer review. In 2014, NREL is working with universities and industry partners to populate additional case studies on OpenEI. The goal is to provide a large enough data set to start conducting analyses of exploration programs to identify correlations between successful exploration plans for areas with similar geologic occurrence models.

  2. EUNIS Underflight Calibrations of CDS, EIT, TRACE, EIS, and EUVI

    NASA Technical Reports Server (NTRS)

    Thomas, Roger J.; Wang, Tongjiang; Rabin, Douglas M.; Jess, David B.

    2008-01-01

    The Extreme-Ultraviolet Normal-Incidence Spectrograph (EUNIS) is a sounding rocket instrument that obtains imaged high-resolution solar spectra. It has now had two successful flights, on 2006 April 12 and 2007 November 16, providing data to support underflight calibrations for a number of orbiting solar experiments on both occasions. A regular part of each campaign is the end-to-end radiometric calibration of the rocket payload carried out at RAL in the UK, using the same facility that provided pre-flight CDS and EIS calibrations. The measurements, traceable to primary radiometric standards, can establish the absolute EUNIS response within a total uncertainty of 10% over its full longwave bandpass of 300-370A. During each EUNIS flight, coordinated observations are made of overlapping solar locations by all participating space experiments, and identified by subsequent image co-registrations, allowing the EUNIS calibrations to be applied to these other instruments as well. The calibration transfer is straightforward for wavelengths within the EUNIS LW bandpass, and is extended to other wavelengths by means of a series of temperature- and density-insensitive line-ratios, with one line of each pair in the calibrated band and the other in the transfer band. In this way, the EUNIS-06 flight is able to update the radiometric calibrations of CDS NISl (and 2nd-order NIS2 near 2x304A), all four channels of EIT, and the three EUV channels of TRACE. The EUNIS-07 flight will further update those missions, as well as both channels of Hinode/EIS and all four channels of STEREO/SECCHI/EUVI. Future EUNIS flights have been proposed that will continue this underflight calibration service. EUNIS is supported by the NASA Heliophysics Division through its Low Cost Access to Space Program in Solar and Heliospheric Physics.

  3. SDO AIA and Hinode EIS observations of "warm" loops

    NASA Astrophysics Data System (ADS)

    Del Zanna, G.; O'Dwyer, B.; Mason, H. E.

    2011-11-01

    We present simultaneous observations of active region "warm" (1 MK) loops using the Solar Dynamics Observatory (SDO) Atmospheric Imaging Assembly (AIA) and Hinode EUV Imaging Spectrometer (EIS). Sample EIS spectra for a loop footpoint and a lop leg region are presented, and are used to describe the spectral lines which contribute to the six AIA EUV channels, both directly and predicted with DEM modeling. We find good overall agreement between observed and predicted count rates for the 131 Å, 193 Å, and 335 Å bands, but highlight a number of problems, partly to be ascribed to inter-calibration issues, partly due to the fact that a large number of lines remain unidentified for the 94 Å, 171 Å, and 211 Å bands. We also found that the 335 Å band is severely affected by cross-talk with the 131 Å band and by second order contributions. We extend our previous work where we highlighted the multi-thermal nature of the SDO AIA bands to show that emission from lines formed at typical transition region temperatures (log T[K] = 5.0-5.8) can be significant for all the EUV channels, and even dominant in some cases. We also assess the possibility of deriving accurate emission measures from the AIA observations. We have found that the inversion of the AIA data to obtain a description of the thermal characteristics of warm loops is unreliable. We highlight the need for further work on the relevant atomic data before the AIA data can be reliably used for plasma diagnostic purposes. Appendices A-C are available in electronic form at http://www.aanda.org

  4. Second Language Acquisition of Spanish /e/ and /ei/ by Native English Speakers

    ERIC Educational Resources Information Center

    Diaz, Miriam; Simonet, Miquel

    2015-01-01

    The present article reports on the findings of a cross-sectional acoustic study of the production of the Spanish /e/-/ei/ contrast, as in "pena-peina" and "reno-reino," by native-English intermediate and advanced learners of Spanish. The acoustic parameter that distinguishes Spanish /e/ from /ei/ is formant change--/e/ is a…

  5. SOLAR-B Mission Extreme Ultraviolet (EUV) Imaging Spectrometer (EIS) Instrument Components

    NASA Technical Reports Server (NTRS)

    Doschek, George A.

    2001-01-01

    This Monthly Progress Report covers the reporting period through June 2001, Phase C/D, Detailed Design and Development Through Launch Plus Thirty Days, for selected components and subsystems of the Extreme ultraviolet Imaging Spectrometer (EIS) instrument, hereafter referred to as EIS Instrument Components. This document contains the program status through the reporting period and forecasts the status for the upcoming reporting period.

  6. SOLAR-B Mission Extreme Ultraviolet (EUV) Imaging Spectrometer (EIS) Instrument Components

    NASA Technical Reports Server (NTRS)

    Doschek, George A.

    2001-01-01

    This Monthly Progress Report covers the reporting period July 2001 of the Detailed Design and Development through Launch plus Thirty Days, Phase C/D, for selected components and subsystems of the Extreme Ultraviolet Imaging Spectrometer (EIS) instrument, hereafter referred to as EIS Instrument Components. This document contains the program status through the reporting period and forecasts the status for the upcoming reporting period.

  7. Second Language Acquisition of Spanish /e/ and /ei/ by Native English Speakers

    ERIC Educational Resources Information Center

    Diaz, Miriam; Simonet, Miquel

    2015-01-01

    The present article reports on the findings of a cross-sectional acoustic study of the production of the Spanish /e/-/ei/ contrast, as in "pena-peina" and "reno-reino," by native-English intermediate and advanced learners of Spanish. The acoustic parameter that distinguishes Spanish /e/ from /ei/ is formant change--/e/ is a…

  8. PEO EIS Delivers Information Dominance to Soldiers in Iraq and Afghanistan

    DTIC Science & Technology

    2009-01-01

    PEO EIS Delivers Information Dominance to Soldiers in Iraq and Afghanistan Jill Finnie In the business world, it is common knowledge that superior...COVERED 00-00-2009 to 00-00-2009 4. TITLE AND SUBTITLE PEO EIS Delivers Information Dominance to Soldiers in Iraq and Afghanistan 5a. CONTRACT

  9. Solar-B Mission Extreme Ultraviolet (EUV) Imaging Spectrometer (EIS) Instrument Components

    NASA Technical Reports Server (NTRS)

    Doschek, George A.

    2002-01-01

    This Monthly Progress Report covers the reporting period August 2002 of the Detailed Design and Development through Launch plus Thirty Days, Phase C/D, for selected components and subsystems of the Extreme ultraviolet Imaging Spectrometer (EIS) instrument, hereafter referred to as EIS Instrument Components. This document contains the program status through the reporting period and forecasts the status for the upcoming reporting period.

  10. Coping Mediates the Relationship between Emotional Intelligence (EI) and Academic Achievement

    ERIC Educational Resources Information Center

    MacCann, Carolyn; Fogarty, Gerard J.; Zeidner, Moshe; Roberts, Richard D.

    2011-01-01

    Research examining the relationships between performance measures of emotional intelligence (EI), coping styles, and academic achievement is sparse. Two studies were designed to redress this imbalance. In each of these studies, both EI and coping styles were significantly related to academic achievement. In Study 1, 159 community college students…

  11. 78 FR 28842 - Searchlight Wind Energy Project Record of Decision (DOE/EIS-0413)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-16

    ... Area Power Administration Searchlight Wind Energy Project Record of Decision (DOE/EIS-0413) AGENCY... Searchlight Wind Energy, LLC (Searchlight) to interconnect its proposed Searchlight Wind Energy Project... Availability of the Final Environmental Impact Statement ] (EIS) for Searchlight Wind Energy Project...

  12. 36 CFR 1010.6 - Determination of requirement for EA or EIS.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Determination of requirement for EA or EIS. 1010.6 Section 1010.6 Parks, Forests, and Public Property PRESIDIO TRUST ENVIRONMENTAL QUALITY § 1010.6 Determination of requirement for EA or EIS. In deciding whether to require the...

  13. 36 CFR § 1010.6 - Determination of requirement for EA or EIS.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 3 2013-07-01 2012-07-01 true Determination of requirement for EA or EIS. § 1010.6 Section § 1010.6 Parks, Forests, and Public Property PRESIDIO TRUST ENVIRONMENTAL QUALITY § 1010.6 Determination of requirement for EA or EIS. In deciding whether to require the...

  14. 36 CFR 1010.6 - Determination of requirement for EA or EIS.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 3 2012-07-01 2012-07-01 false Determination of requirement for EA or EIS. 1010.6 Section 1010.6 Parks, Forests, and Public Property PRESIDIO TRUST ENVIRONMENTAL QUALITY § 1010.6 Determination of requirement for EA or EIS. In deciding whether to require the...

  15. 36 CFR 1010.8 - Actions that normally require an EIS.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Actions that normally require an EIS. 1010.8 Section 1010.8 Parks, Forests, and Public Property PRESIDIO TRUST ENVIRONMENTAL QUALITY § 1010.8 Actions that normally require an EIS. (a) General procedure. So long as a proposed action...

  16. 36 CFR 1010.8 - Actions that normally require an EIS.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 3 2012-07-01 2012-07-01 false Actions that normally require an EIS. 1010.8 Section 1010.8 Parks, Forests, and Public Property PRESIDIO TRUST ENVIRONMENTAL QUALITY § 1010.8 Actions that normally require an EIS. (a) General procedure. So long as a proposed action...

  17. 75 FR 81591 - Notice of Intent to Prepare an Environmental Impact Statement (EIS) for Entry Control...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-28

    ... EIS will address issues associated with ECPs and the on-base roadway network located in Area A of the installation. The EIS will address primary concerns related to the ECPs and existing roadway network where... stakeholders, particularly those in the Fairborn community in close proximity to WPAFB. Handicap assistance and...

  18. 10 CFR 501.65 - Publication of notice of availability of draft EIS.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Publication of notice of availability of draft EIS. 501.65 Section 501.65 Energy DEPARTMENT OF ENERGY (CONTINUED) ALTERNATE FUELS ADMINISTRATIVE PROCEDURES AND SANCTIONS Exemptions and Certifications § 501.65 Publication of notice of availability of draft EIS. A...

  19. 10 CFR 501.65 - Publication of notice of availability of draft EIS.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Publication of notice of availability of draft EIS. 501.65 Section 501.65 Energy DEPARTMENT OF ENERGY (CONTINUED) ALTERNATE FUELS ADMINISTRATIVE PROCEDURES AND SANCTIONS Exemptions and Certifications § 501.65 Publication of notice of availability of draft EIS. A...

  20. 10 CFR 501.65 - Publication of notice of availability of draft EIS.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Publication of notice of availability of draft EIS. 501.65 Section 501.65 Energy DEPARTMENT OF ENERGY (CONTINUED) ALTERNATE FUELS ADMINISTRATIVE PROCEDURES AND SANCTIONS Exemptions and Certifications § 501.65 Publication of notice of availability of draft EIS. A...

  1. 10 CFR 501.65 - Publication of notice of availability of draft EIS.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Publication of notice of availability of draft EIS. 501.65 Section 501.65 Energy DEPARTMENT OF ENERGY (CONTINUED) ALTERNATE FUELS ADMINISTRATIVE PROCEDURES AND SANCTIONS Exemptions and Certifications § 501.65 Publication of notice of availability of draft EIS. A...

  2. 10 CFR 501.65 - Publication of notice of availability of draft EIS.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Publication of notice of availability of draft EIS. 501.65 Section 501.65 Energy DEPARTMENT OF ENERGY (CONTINUED) ALTERNATE FUELS ADMINISTRATIVE PROCEDURES AND SANCTIONS Exemptions and Certifications § 501.65 Publication of notice of availability of draft EIS. A...

  3. 76 FR 78916 - Rice Solar Energy Project Record of Decision (DOE/EIS-0439)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-20

    ... Area Power Administration Rice Solar Energy Project Record of Decision (DOE/EIS-0439) AGENCY: Western... (Western) received a request from Rice Solar Energy, LLC (RSE) to interconnect its proposed Rice Solar... Availability of the Final Environmental Impact Statement (EIS) and Plan Amendment for Rice Solar Energy Project...

  4. 36 CFR 1010.8 - Actions that normally require an EIS.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... an EA to determine if the proposed action or project requires an EIS. Nevertheless, if it is readily... impact on the environment, an EA is not required, and the Trust will prepare or direct the preparation of an EIS without preparing or completing the preparation of an EA. To assist the NEPA...

  5. 12 CFR 1815.108 - Actions that normally require an EIS.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... TREASURY ENVIRONMENTAL QUALITY § 1815.108 Actions that normally require an EIS. (a) If necessary, the Fund shall perform or have performed an environmental assessment to determine if an Application, or any... assessment is not required and the Fund shall immediately begin to prepare, or have prepared, an EIS. (b) An...

  6. Coping Mediates the Relationship between Emotional Intelligence (EI) and Academic Achievement

    ERIC Educational Resources Information Center

    MacCann, Carolyn; Fogarty, Gerard J.; Zeidner, Moshe; Roberts, Richard D.

    2011-01-01

    Research examining the relationships between performance measures of emotional intelligence (EI), coping styles, and academic achievement is sparse. Two studies were designed to redress this imbalance. In each of these studies, both EI and coping styles were significantly related to academic achievement. In Study 1, 159 community college students…

  7. 7 CFR 1955.136 - Environmental Assessment (EA) and Environmental Impact Statement (EIS).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Environmental Impact Statement (EIS). (a) Prior to a final decision on some disposal actions, an environmental assessment must be made and when necessary, an enviornmental impact statement. Detailed guidance on when and... Impact Statement (EIS). 1955.136 Section 1955.136 Agriculture Regulations of the Department of...

  8. 7 CFR 1955.136 - Environmental Assessment (EA) and Environmental Impact Statement (EIS).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Environmental Impact Statement (EIS). (a) Prior to a final decision on some disposal actions, an environmental assessment must be made and when necessary, an enviornmental impact statement. Detailed guidance on when and... Impact Statement (EIS). 1955.136 Section 1955.136 Agriculture Regulations of the Department of...

  9. 7 CFR 1955.136 - Environmental Assessment (EA) and Environmental Impact Statement (EIS).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Environmental Impact Statement (EIS). (a) Prior to a final decision on some disposal actions, an environmental assessment must be made and when necessary, an enviornmental impact statement. Detailed guidance on when and... Impact Statement (EIS). 1955.136 Section 1955.136 Agriculture Regulations of the Department of...

  10. 7 CFR 1955.136 - Environmental Assessment (EA) and Environmental Impact Statement (EIS).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Environmental Impact Statement (EIS). (a) Prior to a final decision on some disposal actions, an environmental assessment must be made and when necessary, an enviornmental impact statement. Detailed guidance on when and... Impact Statement (EIS). 1955.136 Section 1955.136 Agriculture Regulations of the Department of...

  11. Cosubstrate tolerance of the aminoglycoside resistance enzyme Eis from Mycobacterium tuberculosis.

    PubMed

    Chen, Wenjing; Green, Keith D; Garneau-Tsodikova, Sylvie

    2012-11-01

    We previously demonstrated that aminoglycoside acetyltransferases (AACs) display expanded cosubstrate promiscuity. The enhanced intracellular survival (Eis) protein of Mycobacterium tuberculosis is responsible for the resistance of this pathogen to kanamycin A in a large fraction of clinical isolates. Recently, we discovered that Eis is a unique AAC capable of acetylating multiple amine groups on a large pool of aminoglycoside (AG) antibiotics, an unprecedented property among AAC enzymes. Here, we report a detailed study of the acyl-coenzyme A (CoA) cosubstrate profile of Eis. We show that, in contrast to other AACs, Eis efficiently uses only 3 out of 15 tested acyl-CoA derivatives to modify a variety of AGs. We establish that for almost all acyl-CoAs, the number of sites acylated by Eis is smaller than the number of sites acetylated. We demonstrate that the order of n-propionylation of the AG neamine by Eis is the same as the order of its acetylation. We also show that the 6' position is the first to be n-propionylated on amikacin and netilmicin. By sequential acylation reactions, we show that AGs can be acetylated after the maximum possible n-propionylation of their scaffolds by Eis. The information reported herein will advance our understanding of the multiacetylation mechanism of inactivation of AGs by Eis, which is responsible for M. tuberculosis resistance to some AGs.

  12. Invited Reaction: Developing Emotional Intelligence (EI) Abilities through Team-Based Learning

    ERIC Educational Resources Information Center

    Leimbach, Michael P.; Maringka, Jane

    2010-01-01

    The preceding article (Clarke, 2010) examines an important and interesting question; that is, under what conditions can learning contribute to the development of emotional intelligence (EI)? Despite the controversy surrounding the definition and construct of EI, its prevalence for the human resources development (HRD) field and its implications…

  13. Invited Reaction: Developing Emotional Intelligence (EI) Abilities through Team-Based Learning

    ERIC Educational Resources Information Center

    Leimbach, Michael P.; Maringka, Jane

    2010-01-01

    The preceding article (Clarke, 2010) examines an important and interesting question; that is, under what conditions can learning contribute to the development of emotional intelligence (EI)? Despite the controversy surrounding the definition and construct of EI, its prevalence for the human resources development (HRD) field and its implications…

  14. 7 CFR 1940.324 - Adoption of EIS or environmental assessment prepared by another Federal Agency.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 13 2014-01-01 2013-01-01 true Adoption of EIS or environmental assessment prepared... Environmental Program § 1940.324 Adoption of EIS or environmental assessment prepared by another Federal Agency... part of environmental assessments or environmental reviews prepared by other Federal agencies. In this...

  15. 7 CFR 1940.324 - Adoption of EIS or environmental assessment prepared by another Federal Agency.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 13 2011-01-01 2009-01-01 true Adoption of EIS or environmental assessment prepared... Environmental Program § 1940.324 Adoption of EIS or environmental assessment prepared by another Federal Agency... part of environmental assessments or environmental reviews prepared by other Federal agencies. In this...

  16. 7 CFR 1940.324 - Adoption of EIS or environmental assessment prepared by another Federal Agency.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 13 2010-01-01 2009-01-01 true Adoption of EIS or environmental assessment prepared... Environmental Program § 1940.324 Adoption of EIS or environmental assessment prepared by another Federal Agency... part of environmental assessments or environmental reviews prepared by other Federal agencies. In this...

  17. 7 CFR 1940.324 - Adoption of EIS or environmental assessment prepared by another Federal Agency.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 13 2013-01-01 2013-01-01 false Adoption of EIS or environmental assessment prepared... Environmental Program § 1940.324 Adoption of EIS or environmental assessment prepared by another Federal Agency... part of environmental assessments or environmental reviews prepared by other Federal agencies. In this...

  18. 7 CFR 1940.324 - Adoption of EIS or environmental assessment prepared by another Federal Agency.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 13 2012-01-01 2012-01-01 false Adoption of EIS or environmental assessment prepared... Environmental Program § 1940.324 Adoption of EIS or environmental assessment prepared by another Federal Agency... part of environmental assessments or environmental reviews prepared by other Federal agencies. In this...

  19. Current source enhancements in Electrical Impedance Spectroscopy (EIS) to cancel unwanted capacitive effects

    NASA Astrophysics Data System (ADS)

    Zarafshani, Ali; Bach, Thomas; Chatwin, Chris; Xiang, Liangzhong; Zheng, Bin

    2017-03-01

    Electrical Impedance Spectroscopy (EIS) has emerged as a non-invasive imaging modality to detect and quantify functional or electrical properties related to the suspicious tumors in cancer screening, diagnosis and prognosis assessment. A constraint on EIS systems is that the current excitation system suffers from the effects of stray capacitance having a major impact on the hardware subsystem as the EIS is an ill-posed inverse problem which depends on the noise level in EIS measured data and regularization parameter in the reconstruction algorithm. There is high complexity in the design of stable current sources, with stray capacitance reducing the output impedance and bandwidth of the system. To confront this, we have designed an EIS current source which eliminates the effect of stray capacitance and other impacts of the capacitance via a variable inductance. In this paper, we present a combination of operational CCII based on a generalized impedance converter (OCCII-GIC) with a current source. The aim of this study is to use the EIS system as a biomedical imaging technique, which is effective in the early detection of breast cancer. This article begins with the theoretical description of the EIS structure, current source topologies and proposes a current conveyor in application of a Gyrator to eliminate the current source limitations and its development followed by simulation and experimental results. We demonstrated that the new design could achieve a high output impedance over a 3MHz frequency bandwidth when compared to other types of GIC circuits combined with an improved Howland topology.

  20. Greenland outlet glacier dynamics from Extreme Ice Survey (EIS) photogrammetry

    NASA Astrophysics Data System (ADS)

    Hawbecker, P.; Box, J. E.; Balog, J. D.; Ahn, Y.; Benson, R. J.

    2010-12-01

    Time Lapse cameras fill gaps in our observational capabilities: 1. By providing much higher temporal resolution than offered by conventional airborne or satellite remote sensing. 2. While GPS or auto-theodolite observations can provide higher time resolution data than from photogrammetry, survival of these instruments on the hazardous glacier surface is limited, plus, the maintenance of such systems can be more expensive than the maintenance of a terrestrial photogrammetry installation. 3. Imagery provide a high spatial density of observations across the glacier surface, higher than is realistically available from GPS or other in-situ observations. 4. time lapse cameras provide observational capabilities in Eulerian and Lagrangian frames while GPS or theodolite targets, going along for a ride on the glacier, provide only Lagrangian data. Photogrammetry techniques are applied to a year-plus of images from multiple west Greenland glaciers to determine the glacier front horizontal velocity variations at hourly to seasonal time scales. The presentation includes comparisons between glacier front velocities and: 1. surface melt rates inferred from surface air temperature and solar radiation observations; 2. major calving events identified from camera images; 3. surface and near-surface ocean temperature; 4. land-fast sea ice breakup; 5. tidal variations; 6. supra-glacial melt lake drainage events observed in daily optical satellite imagery; and 7.) GPS data. Extreme Ice Survey (EIS) time lapse camera overlooking the Petermann glacier, installed to image glacier dynamics and to capture the predicted ice "island" detachment.

  1. Why does self-reported emotional intelligence predict job performance? A meta-analytic investigation of mixed EI.

    PubMed

    Joseph, Dana L; Jin, Jing; Newman, Daniel A; O'Boyle, Ernest H

    2015-03-01

    Recent empirical reviews have claimed a surprisingly strong relationship between job performance and self-reported emotional intelligence (also commonly called trait EI or mixed EI), suggesting self-reported/mixed EI is one of the best known predictors of job performance (e.g., ρ = .47; Joseph & Newman, 2010b). Results further suggest mixed EI can robustly predict job performance beyond cognitive ability and Big Five personality traits (Joseph & Newman, 2010b; O'Boyle, Humphrey, Pollack, Hawver, & Story, 2011). These criterion-related validity results are problematic, given the paucity of evidence and the questionable construct validity of mixed EI measures themselves. In the current research, we update and reevaluate existing evidence for mixed EI, in light of prior work regarding the content of mixed EI measures. Results of the current meta-analysis demonstrate that (a) the content of mixed EI measures strongly overlaps with a set of well-known psychological constructs (i.e., ability EI, self-efficacy, and self-rated performance, in addition to Conscientiousness, Emotional Stability, Extraversion, and general mental ability; multiple R = .79), (b) an updated estimate of the meta-analytic correlation between mixed EI and supervisor-rated job performance is ρ = .29, and (c) the mixed EI-job performance relationship becomes nil (β = -.02) after controlling for the set of covariates listed above. Findings help to establish the construct validity of mixed EI measures and further support an intuitive theoretical explanation for the uncommonly high association between mixed EI and job performance--mixed EI instruments assess a combination of ability EI and self-perceptions, in addition to personality and cognitive ability.

  2. Sulfonamide-Based Inhibitors of Aminoglycoside Acetyltransferase Eis Abolish Resistance to Kanamycin in Mycobacterium tuberculosis

    SciTech Connect

    Garzan, Atefeh; Willby, Melisa J.; Green, Keith D.; Gajadeera, Chathurada S.; Hou, Caixia; Tsodikov, Oleg V.; Posey, James E.; Garneau-Tsodikova, Sylvie

    2016-12-08

    A two-drug combination therapy where one drug targets an offending cell and the other targets a resistance mechanism to the first drug is a time-tested, yet underexploited approach to combat or prevent drug resistance. By high-throughput screening, we identified a sulfonamide scaffold that served as a pharmacophore to generate inhibitors of Mycobacterium tuberculosis acetyltransferase Eis, whose upregulation causes resistance to the aminoglycoside (AG) antibiotic kanamycin A (KAN) in Mycobacterium tuberculosis. Rational systematic derivatization of this scaffold to maximize Eis inhibition and abolish the Eis-mediated KAN resistance of M. tuberculosis yielded several highly potent agents. A crystal structure of Eis in complex with one of the most potent inhibitors revealed that the inhibitor bound Eis in the AG-binding pocket held by a conformationally malleable region of Eis (residues 28–37) bearing key hydrophobic residues. These Eis inhibitors are promising leads for preclinical development of innovative AG combination therapies against resistant TB.

  3. e-NEPA Guide On Registration And Preparing An EIS For Electronic Submission

    EPA Pesticide Factsheets

    The Guide to e-NEPA Electronic Submittal contains information about e-NEPA, how to register for e-NEPA, and how to prepare your Environmental Impact Statement (EIS) for electronic submission through e-NEPA.

  4. OpenEI: Datasets in the OpenEnergyInfo Data Repository

    DOE Data Explorer

    The Open Energy Information initiative (OpenEI) is a platform to connect the world's energy data. It is a linked open data platform bringing together energy information to provide improved analyses, unique visualizations, and real-time access to data. OpenEI follows guidelines set by the White House Open Government Initiative , which is focused on transparency, collaboration, and participation. OpenEI strives to provide open access to this energy information, with the ultimate goal of spurring creativity and driving innovation in the energy sector.[Copied from the OpenEI Wiki main page]. It features a wiki, a blog, a list of information gateways, and a browsing list of deposited data sets.

  5. Unusual regioversatility of acetyltransferase Eis, a cause of drug resistance in XDR-TB

    SciTech Connect

    Chen, Wenjing; Biswas, Tapan; Porter, Vanessa R.; Tsodikov, Oleg V.; Garneau-Tsodikova, Sylvie

    2011-09-06

    The emergence of multidrug-resistant and extensively drug-resistant (XDR) tuberculosis (TB) is a serious global threat. Aminoglycoside antibiotics are used as a last resort to treat XDR-TB. Resistance to the aminoglycoside kanamycin is a hallmark of XDR-TB. Here, we reveal the function and structure of the mycobacterial protein Eis responsible for resistance to kanamycin in a significant fraction of kanamycin-resistant Mycobacterium tuberculosis clinical isolates. We demonstrate that Eis has an unprecedented ability to acetylate multiple amines of many aminoglycosides. Structural and mutagenesis studies of Eis indicate that its acetylation mechanism is enabled by a complex tripartite fold that includes two general control non-derepressible 5 (GCN5)-related N-acetyltransferase regions. An intricate negatively charged substrate-binding pocket of Eis is a potential target of new antitubercular drugs expected to overcome aminoglycoside resistance.

  6. Computer graphics for management: An abstract of capabilities and applications of the EIS system

    NASA Technical Reports Server (NTRS)

    Solem, B. J.

    1975-01-01

    The Executive Information Services (EIS) system, developed as a computer-based, time-sharing tool for making and implementing management decisions, and including computer graphics capabilities, was described. The following resources are available through the EIS languages: centralized corporate/gov't data base, customized and working data bases, report writing, general computational capability, specialized routines, modeling/programming capability, and graphics. Nearly all EIS graphs can be created by a single, on-line instruction. A large number of options are available, such as selection of graphic form, line control, shading, placement on the page, multiple images on a page, control of scaling and labeling, plotting of cum data sets, optical grid lines, and stack charts. The following are examples of areas in which the EIS system may be used: research, estimating services, planning, budgeting, and performance measurement, national computer hook-up negotiations.

  7. Notification: National Environmental Policy Act (NEPA) Environmental Impact Statements (EIS) Reviews

    EPA Pesticide Factsheets

    October 29, 2012. The EPA's OIG plans to begin preliminary research on EPA’s reviews of National Environmental Policy Act (NEPA) environmental impact statements (EIS) as submitted to EPA under Section 309 of the Clean Air Act.

  8. Unusual regioversatility of acetyltransferase Eis, a cause of drug resistance in XDR-TB.

    PubMed

    Chen, Wenjing; Biswas, Tapan; Porter, Vanessa R; Tsodikov, Oleg V; Garneau-Tsodikova, Sylvie

    2011-06-14

    The emergence of multidrug-resistant and extensively drug-resistant (XDR) tuberculosis (TB) is a serious global threat. Aminoglycoside antibiotics are used as a last resort to treat XDR-TB. Resistance to the aminoglycoside kanamycin is a hallmark of XDR-TB. Here, we reveal the function and structure of the mycobacterial protein Eis responsible for resistance to kanamycin in a significant fraction of kanamycin-resistant Mycobacterium tuberculosis clinical isolates. We demonstrate that Eis has an unprecedented ability to acetylate multiple amines of many aminoglycosides. Structural and mutagenesis studies of Eis indicate that its acetylation mechanism is enabled by a complex tripartite fold that includes two general control non-derepressible 5 (GCN5)-related N-acetyltransferase regions. An intricate negatively charged substrate-binding pocket of Eis is a potential target of new antitubercular drugs expected to overcome aminoglycoside resistance.

  9. Potent Inhibitors of Acetyltransferase Eis Overcome Kanamycin Resistance in Mycobacterium tuberculosis.

    PubMed

    Willby, Melisa J; Green, Keith D; Gajadeera, Chathurada S; Hou, Caixia; Tsodikov, Oleg V; Posey, James E; Garneau-Tsodikova, Sylvie

    2016-06-17

    A major cause of tuberculosis (TB) resistance to the aminoglycoside kanamycin (KAN) is the Mycobacterium tuberculosis (Mtb) acetyltransferase Eis. Upregulation of this enzyme is responsible for inactivation of KAN through acetylation of its amino groups. A 123 000-compound high-throughput screen (HTS) yielded several small-molecule Eis inhibitors that share an isothiazole S,S-dioxide heterocyclic core. These were investigated for their structure-activity relationships. Crystal structures of Eis in complex with two potent inhibitors show that these molecules are bound in the conformationally adaptable aminoglycoside binding site of the enzyme, thereby obstructing binding of KAN for acetylation. Importantly, we demonstrate that several Eis inhibitors, when used in combination with KAN against resistant Mtb, efficiently overcome KAN resistance. This approach paves the way toward development of novel combination therapies against aminoglycoside-resistant TB.

  10. Comparison of Printed Bibliographic Descriptions Distributed by BIOSIS, CAS, and Ei

    ERIC Educational Resources Information Center

    Larson, Julian R.; And Others

    1976-01-01

    Printed bibliographic descriptions of journal articles cited by BioSciences Information Service of Biological Abstracts (BIOSIS), Chemical Abstracts Service (CAS), and Engineering Index (Ei) were compared to identify similarities and differences in form, format, and data content. (Author)

  11. Comparison of Printed Bibliographic Descriptions Distributed by BIOSIS, CAS, and Ei

    ERIC Educational Resources Information Center

    Larson, Julian R.; And Others

    1976-01-01

    Printed bibliographic descriptions of journal articles cited by BioSciences Information Service of Biological Abstracts (BIOSIS), Chemical Abstracts Service (CAS), and Engineering Index (Ei) were compared to identify similarities and differences in form, format, and data content. (Author)

  12. 7 CFR 650.20 - Reviewing and commenting on EIS's prepared by other agencies.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...? What benefits are foregone if prime farmland is taken? (8) Impacts on ecosystems. Does the EIS describe impacts on major plant communities, and terrestrial and aquatic ecosystems? (9) Impacts on NRCS-assisted...

  13. 7 CFR 650.20 - Reviewing and commenting on EIS's prepared by other agencies.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...? What benefits are foregone if prime farmland is taken? (8) Impacts on ecosystems. Does the EIS describe impacts on major plant communities, and terrestrial and aquatic ecosystems? (9) Impacts on NRCS-assisted...

  14. Subcellular Localization of the Intracellular Survival-Enhancing Eis Protein of Mycobacterium tuberculosis

    PubMed Central

    Dahl, John L.; Wei, Jun; Moulder, James W.; Laal, Suman; Friedman, Richard L.

    2001-01-01

    Mycobacterium tuberculosis is a facultative intracellular pathogen that has evolved the ability to survive and multiply within human macrophages. It is not clear how M. tuberculosis avoids the destructive action of macrophages, but this ability is fundamental in the pathogenicity of tuberculosis. A gene previously identified in M. tuberculosis, designated eis, was found to enhance intracellular survival of Mycobacterium smegmatis in the human macrophage-like cell line U-937 (J. Wei et al., J. Bacteriol. 182:377–384, 2000). When eis was introduced into M. smegmatis on a multicopy vector, sodium dodecyl sulfate-polyacrylamide gel electrophoresis revealed the appearance of a unique 42-kDa protein band corresponding to the predicted molecular weight of the eis gene product. This band was electroeluted from the gel with a purity of >90% and subjected to N-terminal amino acid sequencing, which demonstrated that the 42-kDa band was indeed the protein product of eis. The Eis protein produced by M. tuberculosis H37Ra had an identical N-terminal amino acid sequence. A synthetic polypeptide corresponding to a carboxyl-terminal region of the deduced eis protein sequence was used to generate affinity-purified rabbit polyclonal antibodies that reacted with the 42-kDa protein in Western blot analysis. Hydropathy profile analysis showed the Eis protein to be predominantly hydrophilic with a potential hydrophobic amino terminus. Phase separation of M. tuberculosis H37Ra lysates by the nonionic detergent Triton X-114 revealed the Eis protein in both the aqueous and detergent phases. After fractionation of M. tuberculosis by differential centrifugation, Eis protein appeared mainly in the cytoplasmic fraction but also in the membrane, cell wall, and culture supernatant fractions as well. Forty percent of the sera from pulmonary tuberculosis patients tested for anti-Eis antibody gave positive reactions in Western blot analysis. Although the function of Eis remains unknown, evidence

  15. 36 CFR § 1010.8 - Actions that normally require an EIS.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 3 2013-07-01 2012-07-01 true Actions that normally require an EIS. § 1010.8 Section § 1010.8 Parks, Forests, and Public Property PRESIDIO TRUST ENVIRONMENTAL QUALITY § 1010.8 Actions that normally require an EIS. (a) General procedure. So long as a proposed action...

  16. The role of data in the EIS process: Evidence from the BLM wilderness review

    SciTech Connect

    Ginger, C.; Mohai, P. )

    1993-03-01

    Various propositions have been offered about the role of the environmental impact statement (EIS) in agency decision making. These include statements that agencies are (1) using the information collected in the EIS to make rational decisions; (2) justifying decisions made a priori; (3) using the EIS to gain support or consensus for projects; or (4) simply fulfilling a legal mandate, with the EIS having no substantive impact on decisions. Previous studies regarding the role of EIS data have focused on the quality of the data in the EIS and whether or not the data are related to decisions. The role of site-specific information in the Bureau of Land Management (BLM) wilderness EIS process is analyzed and the results are used to reflect on the impact of the EIS in agency decision making. These results are compared with an earlier analysis of the Forest Service's Second Roadless Area Review and Evaluation (RARE II). The results of the statistical analyses of three sets of BLM wilderness EISs indicate that although some of the site-specific information about resource potential is statistically related to agency wilderness recommendations, the vast majority of the information is not. In addition, in some cases, the information was related to wilderness recommendations in a counterintuitive direction. Overall, of the 190 measures of resource potential found in these documents, only 17 (9%) were statistically related to BLM recommendations in an intuitive direction. The fact that most of the information in these EISs is not statistically related to decisions lends support to the proposition that the agency was primarily fulfilling the legally mandated procedure of the National Environmental Policy Act in producing these EISs, rather than achieving the spirit of the law. Results from the analysis of the Forest Service's RARE II wilderness review are similar.

  17. EUNIS Underflight Calibrations of CDS, EIT, TRACE, EIS, and EUVI

    NASA Technical Reports Server (NTRS)

    Thomas, Roger J.; Rabin, Douglas M.; Jess, David B.; Wang, Tongjiang

    2008-01-01

    The Extreme-Ultraviolet Normal-Incidence Spectrograph (EUNIS) is a sounding rocket instrument that obtains imaged high-resolution solar spectra. It has now had two successful flights, on 2006 April 12 and 2007 November 16, providing data to support underflight calibrations for a number of orbiting solar experiments on both occasions. A regular part of each campaign is the end-to-end radiometric calibration of the rocket payload carried out at RAL in the UK, using the same facility that provided pre-flight CDS and EIS calibrations. The measurements, traceable to primary radiometric standards, can establish the absolute EUNIS response within a relative uncertainty of 10% over its full longwave bandpass of 300-370A. During each EUNIS flight, coordinated observations are made of overlapping solar locations by all participating space experiments, and identified by subsequent image co-registrations, allowing the EUNIS calibrations to be applied to these other instruments as well. The calibration transfer is straightforward for wavelengths within the EUNIS LW bandpass, and is extended to other wavelengths by means of a series of 'insensitive' line-ratios, with one line of each pair in the calibrated band and the other in the transfer band. In this way, the EUNIS-06 flight is able to update the radiometric calibrations of CDS NISl (plus 2nd order NIS2 near 2x304A), all four channels of EIT, and the three EUV channels of TRACE. The EUNIS-07 flight will further update those missions, as well as both channels of Hinode/EIT and all four channels of STEREO/SECCHI/EUVI. Future EUNIS flights have been proposed that will continue this underflight calibration service. EUNIS is supported by the NASA Heliophysics Division through its Low Cost Access to Space Program in Solar and Heliospheric Physics.

  18. Das Isotopenthermometer im ewigen Eis: Mechanismen globaler Klimaschwankungen

    NASA Astrophysics Data System (ADS)

    Stauffer, Bernhard

    Die Analysen von zwei Bohrkernen im grönländischen Eis haben unser Wissen über Klimaschwankungen und deren mögliche Ursachen stark erweitert. Die 18 O-Messreihe zeigt, dass der Übergang von der letzten Eiszeit zur Nacheiszeit in drastischen Sprüngen erfolgte und dass es auch während der Eiszeit schnelle, drastische Klimaänderungen, so genannte Dansgaard-Oeschger -Ereignisse gab. Basierend auf der heute gültigen Beziehung zwischen mittlerer Jahrestemperatur und 18 O-Wert nahm man an, dass der Temperaturanstieg zwischen Eiszeitmaximum und Nacheiszeit rund 12°C und zu Beginn eines Dansgaard-Oeschge-Ereignisses rund 8°C betrugen. Neue Kalibrationsmethoden haben gezeigt, dass die Temperatursprünge praktisch doppelt so groß waren, wie die mit der Dansgaard-Beziehung ermittelten. Erstaunlich sind vor allem die schnellen Temperaturanstiege. Ein Temperaturanstieg von mehr als 10°C e folgte oft in wenigen Jahrzehnten. Die Methanmessreihe ergab, dass die Dansgaard-Oeschger -Ereignisse kein auf Grönland beschränktes Phänomen sind. Es sind Klimaschwankungen von globaler Bedeutung. Die zeitliche Synchronisation von Messreihen auf Grönland und der Antarktis mithilfe von Methanvariationen ergab, dass einer abrupten Erwärmung in Grönland oft eine Erwärmung in der Antarktis vorausging. Von zwei Kernbohrungen im Rahmen des European Project for Ice Coring in Antarctica erwartet man vor allem neue Erkenntnisse über Klimawechselwirkungen zwischen den beiden Hemisphären und über die Ursachen der Variationen von Treibhausgaskonzentrationen parallel zu globalen Klimaschwankungen.

  19. UNDERFLIGHT CALIBRATION OF SOHO/CDS AND HINODE/EIS WITH EUNIS-07

    SciTech Connect

    Wang Tongjiang; Brosius, Jeffrey W.; Thomas, Roger J.; Rabin, Douglas M.; Davila, Joseph M.; Young, Peter R.; Del Zanna, Giulio

    2011-12-01

    Flights of Goddard Space Flight Center's Extreme Ultraviolet Normal Incidence Spectrograph (EUNIS) sounding rocket in 2006 and 2007 provided updated radiometric calibrations for Solar and Heliospheric Observatory/Coronal Diagnostic Spectrometer (SOHO/CDS) and Hinode/Extreme Ultraviolet Imaging Spectrometer (Hinode/EIS). EUNIS carried two independent imaging spectrographs covering wavebands of 300-370 A in first order and 170-205 A in second order. After each flight, end-to-end radiometric calibrations of the rocket payload were carried out in the same facility used for pre-launch calibrations of CDS and EIS. During the 2007 flight, EUNIS, SOHO/CDS, and Hinode/EIS observed the same solar locations, allowing the EUNIS calibrations to be directly applied to both CDS and EIS. The measured CDS NIS 1 line intensities calibrated with the standard (version 4) responsivities with the standard long-term corrections are found to be too low by a factor of 1.5 due to the decrease in responsivity. The EIS calibration update is performed in two ways. One uses the direct calibration transfer of the calibrated EUNIS-07 short wavelength (SW) channel. The other uses the insensitive line pairs, in which one member was observed by the EUNIS-07 long wavelength (LW) channel and the other by EIS in either the LW or SW waveband. Measurements from both methods are in good agreement, and confirm (within the measurement uncertainties) the EIS responsivity measured directly before the instrument's launch. The measurements also suggest that the EIS responsivity decreased by a factor of about 1.2 after the first year of operation (although the size of the measurement uncertainties is comparable to this decrease). The shape of the EIS SW response curve obtained by EUNIS-07 is consistent with the one measured in laboratory prior to launch. The absolute value of the quiet-Sun He II 304 A intensity measured by EUNIS-07 is consistent with the radiance measured by CDS NIS in quiet regions near the

  20. Time series forecasting of future claims amount of SOCSO's employment injury scheme (EIS)

    NASA Astrophysics Data System (ADS)

    Zulkifli, Faiz; Ismail, Isma Liana; Chek, Mohd Zaki Awang; Jamal, Nur Faezah; Ridzwan, Ahmad Nur Azam Ahmad; Jelas, Imran Md; Noor, Syamsul Ikram Mohd; Ahmad, Abu Bakar

    2012-09-01

    The Employment Injury Scheme (EIS) provides protection to employees who are injured due to accidents whilst working, commuting from home to the work place or during employee takes a break during an authorized recess time or while travelling that is related with his work. The main purpose of this study is to forecast value on claims amount of EIS for the year 2011 until 2015 by using appropriate models. These models were tested on the actual EIS data from year 1972 until year 2010. Three different forecasting models are chosen for comparisons. These are the Naïve with Trend Model, Average Percent Change Model and Double Exponential Smoothing Model. The best model is selected based on the smallest value of error measures using the Mean Squared Error (MSE) and Mean Absolute Percentage Error (MAPE). From the result, the best model that best fit the forecast for the EIS is the Average Percent Change Model. Furthermore, the result also shows the claims amount of EIS for the year 2011 to year 2015 continue to trend upwards from year 2010.

  1. A background correction algorithm for Van Allen Probes MagEIS electron flux measurements

    DOE PAGES

    Claudepierre, S. G.; O'Brien, T. P.; Blake, J. B.; ...

    2015-07-14

    We describe an automated computer algorithm designed to remove background contamination from the Van Allen Probes Magnetic Electron Ion Spectrometer (MagEIS) electron flux measurements. We provide a detailed description of the algorithm with illustrative examples from on-orbit data. We find two primary sources of background contamination in the MagEIS electron data: inner zone protons and bremsstrahlung X-rays generated by energetic electrons interacting with the spacecraft material. Bremsstrahlung X-rays primarily produce contamination in the lower energy MagEIS electron channels (~30–500 keV) and in regions of geospace where multi-M eV electrons are present. Inner zone protons produce contamination in all MagEIS energymore » channels at roughly L < 2.5. The background-corrected MagEIS electron data produce a more accurate measurement of the electron radiation belts, as most earlier measurements suffer from unquantifiable and uncorrectable contamination in this harsh region of the near-Earth space environment. These background-corrected data will also be useful for spacecraft engineering purposes, providing ground truth for the near-Earth electron environment and informing the next generation of spacecraft design models (e.g., AE9).« less

  2. Van Allen Probes ECT/MagEIS Background Corrected Electron Flux Measurements: Methods and Initial Findings

    NASA Astrophysics Data System (ADS)

    Claudepierre, S. G.; O'Brien, T. P., III; Blake, J. B.; Fennell, J.; Looper, M. D.; Clemmons, J. H.; Roeder, J. L.; Mazur, J. E.; Mulligan, T. L.

    2014-12-01

    We present results from the Magnetic Electron Ion Spectrometer (MagEIS) instrument, part ofthe Energetic Composition and Thermal Plasma (ECT) Suite, onboard the NASA Van AllenProbes spacecraft. The ECT/MagEIS instrument measures radiation belt electrons in the ~20-4000 keV energy range and protons in the ~60-1000 keV energy range, with high resolution inboth energy and pitch-angle. In addition, the MagEIS electron measurement technique allowsfor a full quantification of the source(s) of background contamination in the measurement.MagEIS is thus able to make clean, reliable electron flux observations in the presence of strongpenetrating backgrounds, for example, contamination from relativistic protons in the inner zoneand inner slot region. We summarize our background correction algorithm, describe the varioussources of background contamination, and present an overview of our initial findings using thebackground corrected data set. Understanding the causes and effects of backgroundcontamination in the MagEIS electron data set is crucial for the interpretation and proper use ofsuch data. The techniques described will facilitate new investigations into the dynamics of theEarth's electron radiation belts, which have thus far not been possible.

  3. A background correction algorithm for Van Allen Probes MagEIS electron flux measurements

    SciTech Connect

    Claudepierre, S. G.; O'Brien, T. P.; Blake, J. B.; Fennell, J. F.; Roeder, J. L.; Clemmons, J. H.; Looper, M. D.; Mazur, J. E.; Mulligan, T. M.; Spence, H. E.; Reeves, G. D.; Friedel, R. H. W.; Henderson, M. G.; Larsen, B. A.

    2015-07-14

    We describe an automated computer algorithm designed to remove background contamination from the Van Allen Probes Magnetic Electron Ion Spectrometer (MagEIS) electron flux measurements. We provide a detailed description of the algorithm with illustrative examples from on-orbit data. We find two primary sources of background contamination in the MagEIS electron data: inner zone protons and bremsstrahlung X-rays generated by energetic electrons interacting with the spacecraft material. Bremsstrahlung X-rays primarily produce contamination in the lower energy MagEIS electron channels (~30–500 keV) and in regions of geospace where multi-M eV electrons are present. Inner zone protons produce contamination in all MagEIS energy channels at roughly L < 2.5. The background-corrected MagEIS electron data produce a more accurate measurement of the electron radiation belts, as most earlier measurements suffer from unquantifiable and uncorrectable contamination in this harsh region of the near-Earth space environment. These background-corrected data will also be useful for spacecraft engineering purposes, providing ground truth for the near-Earth electron environment and informing the next generation of spacecraft design models (e.g., AE9).

  4. eis Promoter C14G and C15G Mutations Do Not Confer Kanamycin Resistance in Mycobacterium tuberculosis.

    PubMed

    Pholwat, Suporn; Stroup, Suzanne; Heysell, Scott; Ogarkov, Oleg; Zhdanova, Svetlana; Ramakrishnan, Girija; Houpt, Eric

    2016-12-01

    We studied the significance of particular eis mutations on Mycobacterium tuberculosis drug resistance using a specialized transduction strategy. Recombinant strains harboring eis promoter mutations C14T, C12T, and G10A exhibited kanamycin resistance with MICs of 40, 10, and 20 μg/ml, respectively, while recombinant strains harboring C14G and C15G mutations were kanamycin susceptible (MIC, 2.5 to 5 μg/ml). Each of the eis mutants tested remained amikacin susceptible (MIC, 0.5 to 4 μg/ml). The identification of specific eis mutations is needed for accurate genotypic susceptibility testing for kanamycin.

  5. Multi-Criteria Decision Analysis Framework in the Selection of an Enterprise Integration (EI) Approach That Best Satisfies Organizational Requirements

    ERIC Educational Resources Information Center

    Ngeru, James

    2012-01-01

    In the past few decades, adoption of Enterprise Integration (EI) through initiatives such as Service Oriented Architecture (SOA), Enterprise Application Integration (EAI) and Enterprise Resource Planning (ERP) has consistently dominated most of organizations' top strategic priorities. Additionally, the field of EI has generated a vast amount…

  6. 75 FR 16828 - Notice of Intent To Prepare and Scope an Environmental Impact Statement (EIS) for the Outer...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-02

    .... Comments on the relationship between the Oil and Gas Program and the Alternative Energy Program are also... alternatives that should be evaluated in the EIS. The EIS will analyze the potential impacts of the adoption of... degradation of marine and coastal habitats. Additionally, alternatives will be developed and analyzed during...

  7. 75 FR 13131 - Notice of Intent To Prepare an Environmental Impact Statement (EIS) for the Sale of Plum Island, NY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-18

    ... ADMINISTRATION Notice of Intent To Prepare an Environmental Impact Statement (EIS) for the Sale of Plum Island... Agency, announces its Notice of Intent (NOI) to prepare an EIS for the anticipated sale of Plum Island..., Boston, MA 02222. All comments received by GSA in response to the Plum Island NEPA process, including...

  8. 76 FR 2903 - Interconnection of the Proposed Hyde County Wind Energy Center Project (DOE/EIS-0461), and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-18

    ... Area Power Administration Interconnection of the Proposed Hyde County Wind Energy Center Project (DOE/EIS-0461), and Proposed Crowned Ridge Wind Energy Center Project (DOE/EIS-0462) AGENCY: Western Area... statements (EISs) for the Hyde County Wind Energy Center Project and the Crowned Ridge Wind Energy...

  9. 76 FR 376 - Notice of Scoping Meetings on the Environmental Impact Statement (EIS) for the Proposed 2012-2017...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-04

    ... Environmental Impact Statement (EIS) for the Proposed 2012-2017 Outer Continental Shelf (OCS) Oil and Gas... prepare a Programmatic EIS for the proposed OCS Oil and Gas Leasing Program for 2012-2017 and request for... development through 2017. Therefore, meetings will not be held in these areas. The Western Gulf of Mexico...

  10. 75 FR 17761 - Termination of an Environmental Impact Statement (EIS) for the General Management Plan (GMP) for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-07

    ... National Park Service Termination of an Environmental Impact Statement (EIS) for the General Management... the continuation of current management policies and practices. Alternative B would expand interpretive... scoping newsletter. The NPS has since determined that an Environmental Assessment rather than an EIS is...

  11. Multi-Criteria Decision Analysis Framework in the Selection of an Enterprise Integration (EI) Approach That Best Satisfies Organizational Requirements

    ERIC Educational Resources Information Center

    Ngeru, James

    2012-01-01

    In the past few decades, adoption of Enterprise Integration (EI) through initiatives such as Service Oriented Architecture (SOA), Enterprise Application Integration (EAI) and Enterprise Resource Planning (ERP) has consistently dominated most of organizations' top strategic priorities. Additionally, the field of EI has generated a vast amount…

  12. 7 CFR 1940.313 - Actions that normally require the preparation of an Environmental Impact Statement (EIS).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Environmental Impact Statement (EIS). 1940.313 Section 1940.313 Agriculture Regulations of the Department of... Environmental Program § 1940.313 Actions that normally require the preparation of an Environmental Impact Statement (EIS). The environmental assessment process will be used, as defined in this subpart, to identify...

  13. 7 CFR 1940.313 - Actions that normally require the preparation of an Environmental Impact Statement (EIS).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Environmental Impact Statement (EIS). 1940.313 Section 1940.313 Agriculture Regulations of the Department of... Environmental Program § 1940.313 Actions that normally require the preparation of an Environmental Impact Statement (EIS). The environmental assessment process will be used, as defined in this subpart, to identify...

  14. 7 CFR 1940.313 - Actions that normally require the preparation of an Environmental Impact Statement (EIS).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Environmental Impact Statement (EIS). 1940.313 Section 1940.313 Agriculture Regulations of the Department of... Environmental Program § 1940.313 Actions that normally require the preparation of an Environmental Impact Statement (EIS). The environmental assessment process will be used, as defined in this subpart, to identify...

  15. 7 CFR 1940.313 - Actions that normally require the preparation of an Environmental Impact Statement (EIS).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Environmental Impact Statement (EIS). 1940.313 Section 1940.313 Agriculture Regulations of the Department of... Environmental Program § 1940.313 Actions that normally require the preparation of an Environmental Impact Statement (EIS). The environmental assessment process will be used, as defined in this subpart, to identify...

  16. The Feasibility of Training and Development of EI: An Exploratory Study in Singapore, Hong Kong and Taiwan

    ERIC Educational Resources Information Center

    Wong, Chi-Sum; Foo, Maw-Der; Wang, Cheng-Wen; Wong, Ping-Man

    2007-01-01

    Emotional intelligence (EI) has been an emerging topic for psychological, educational, and management researchers and consultants in recent years. However, existing literature has concentrated on demonstrating the effects of EI on either the mental health or on job outcomes such as job attitudes and performance. There is relatively little…

  17. 78 FR 28699 - Notice to Rescind a Notice of Intent To Prepare an Environmental Impact Statement (EIS): Dickson...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-15

    ... to prepare an Environmental Impact Statement (EIS) for a proposed transportation project in Dickson... Federal Highway Administration Notice to Rescind a Notice of Intent To Prepare an Environmental Impact... to prepare an Environmental Impact Statement (EIS). SUMMARY: The Federal Highway Administration (FHWA...

  18. Comparative Study of Eis-like Enzymes from Pathogenic and Nonpathogenic Bacteria

    PubMed Central

    Green, Keith D.; Pricer, Rachel E.; Stewart, Megan N.; Garneau-Tsodikova, Sylvie

    2016-01-01

    Antibiotic resistance is a growing problem worldwide. Of particular importance is the resistance of Mycobacterium tuberculosis (Mtb) to currently available antibiotics used in the treatment of infected patients. Up-regulation of an aminoglycoside (AG) acetyltransferase, the enhanced intracellular survival (Eis) protein of Mtb (Eis_Mtb), is responsible for resistance to the second-line injectable drug kanamycin A in a number of Mtb clinical isolates. This acetyltransferase is known to modify AGs, not at a single position, as usual for this type of enzyme, but at multiple amine sites. We identified, using in silico techniques, 22 homologues from a wide variety of bacteria, that we then cloned, purified, and biochemically studied. From the selected Eis homologues, 7 showed the ability to modify AGs to various degrees and displayed both similarities and differences when compared to Eis_Mtb. In addition, an inhibitor proved to be active against all homologues tested. Our findings show that this family of acetyltransferase enzymes exists in both mycobacteria and non-mycobacteria and in both pathogenic and nonpathogenic species. The bacterial strains described herein should be monitored for rising resistance rates to AGs. PMID:27622743

  19. 75 FR 17765 - Termination of Environmental Impact Statement (EIS) for the Special Resource Study (SRS) for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-07

    ... (SRS) for Castle Nugent Farms, St. Croix, U.S. Virgin Islands in favor of an Environmental Assessment..., St. Croix, U.S. Virgin Islands. A Notice of Intent to prepare an EIS for the SRS was published in the... located on the island of St. Croix in the U.S. Virgin Islands. The SRS will determine whether study area...

  20. 77 FR 43046 - Lolo National Forest; Montana; Center Horse Landscape Restoration EIS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-23

    ... Forest Service Lolo National Forest; Montana; Center Horse Landscape Restoration EIS AGENCY: Forest Service, USDA. ACTION: Notice of intent to prepare an environmental impact statement. SUMMARY: The Forest... within the Monture, Dunham, Shanley, Cottonwood and Spring Creek drainages, Lolo National Forest,...

  1. 7 CFR 1955.136 - Environmental Assessment (EA) and Environmental Impact Statement (EIS).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 14 2010-01-01 2009-01-01 true Environmental Assessment (EA) and Environmental Impact... Disposal of Inventory Property General § 1955.136 Environmental Assessment (EA) and Environmental Impact Statement (EIS). (a) Prior to a final decision on some disposal actions, an environmental assessment must be...

  2. 75 FR 60089 - Final Environmental Impact Statement (EIS) Addressing Campus Development at Fort Meade

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-29

    ... . Additional copies of the Final EIS are available at the Fort Meade Main Post Library, 4418 Llewellyn Avenue, Fort Meade, MD 20755; the Anne Arundel County Public Library North County Area Branch, 1010 Eastway, Glen Burnie, MD 21060; and the Anne Arundel County Public Library West County Area Branch, 1325...

  3. 75 FR 76444 - Environmental Impact Statement (EIS) for Construction and Operation of a Panoramic Survey...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF DEFENSE Department of the Air Force Environmental Impact Statement (EIS) for Construction and Operation of a Panoramic Survey Telescope and Rapid Response System (Pan-STARRS) at the Summit of Mauna Kea, HI ACTION...

  4. An Exploration of the Relationship between Emotional Intelligence (EI) and the Multiple Mini-Interview (MMI)

    ERIC Educational Resources Information Center

    Yen, Wendy; Hovey, Richard; Hodwitz, Kathryn; Zhang, Su

    2011-01-01

    The present study explored the relationship between the Multiple Mini-Interview (MMI) admissions process and the Bar-On EQ-i emotional intelligence (EI) instrument in order to investigate the potential for the EQ-i to serve as a proxy measure to the MMI. Participants were 196 health science candidates who completed both the MMI and the EQ-i as…

  5. The Iterative Use of Single Case Research Designs to Advance the Science of EI/ECSE

    ERIC Educational Resources Information Center

    Barton, Erin E.; Ledford, Jennifer R.; Lane, Justin D.; Decker, Jessica; Germansky, Sara E.; Hemmeter, Mary Louise; Kaiser, Ann

    2016-01-01

    Research in early intervention/early childhood special education (EI/ECSE) is focused on identifying effective practices related to positive outcomes for young children with disabilities and their families. Individual responses to evidence-based practices are often variable, and non-responders are common. Single case research (SCR) might be…

  6. 75 FR 3746 - Ryan White HIV/AIDS Part C Early Intervention Services (EIS) Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-22

    ... HUMAN SERVICES Health Resources and Services Administration Ryan White HIV/AIDS Part C Early..., Florida, that will ensure continuity of Part C, Early Intervention Services (EIS), HIV/AIDS care and...: Critical funding for HIV/AIDS care and treatment to the target populations in Orange County,...

  7. Overexpression of the chromosomally encoded aminoglycoside acetyltransferase eis confers kanamycin resistance in Mycobacterium tuberculosis.

    PubMed

    Zaunbrecher, M Analise; Sikes, R David; Metchock, Beverly; Shinnick, Thomas M; Posey, James E

    2009-11-24

    The emergence of multidrug-resistant (MDR) tuberculosis (TB) highlights the urgent need to understand the mechanisms of resistance to the drugs used to treat this disease. The aminoglycosides kanamycin and amikacin are important bactericidal drugs used to treat MDR TB, and resistance to one or both of these drugs is a defining characteristic of extensively drug-resistant TB. We identified mutations in the -10 and -35 promoter region of the eis gene, which encodes a previously uncharacterized aminoglycoside acetyltransferase. These mutations led to a 20-180-fold increase in the amount of eis leaderless mRNA transcript, with a corresponding increase in protein expression. Importantly, these promoter mutations conferred resistance to kanamycin [5 microg/mL < minimum inhibitory concentration (MIC) eis promoter mutations. These results have important clinical implications in that clinical isolates determined to be resistant to kanamycin may not be cross-resistant to amikacin, as is often assumed. Molecular detection of eis mutations should distinguish strains resistant to kanamycin and those resistant to kanamycin and amikacin. This may help avoid excluding a potentially effective drug from a treatment regimen for drug-resistant TB.

  8. 78 FR 29124 - Draft Environmental Impact Statement (EIS) for the Implementation of Energy, Water, and Solid...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-17

    ... plant (Alternative 4); construction and operation of a geothermal energy facility (Alternative 5); and... Department of the Army Draft Environmental Impact Statement (EIS) for the Implementation of Energy, Water... implement Net Zero energy, water and waste initiatives by 2020 at Fort Bliss to meet mandates for...

  9. 36 CFR § 907.7 - Determination of requirement for EIS.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... CORPORATION ENVIRONMENTAL QUALITY § 907.7 Determination of requirement for EIS. Determining whether to prepare an environmental impact statement is the first step in applying the NEPA process. In deciding whether to prepare an environmental impact statement, the responsible Corporation official will determine...

  10. 36 CFR § 907.8 - Actions that normally require an EIS.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... CORPORATION ENVIRONMENTAL QUALITY § 907.8 Actions that normally require an EIS. PADC shall perform or have performed an environmental assessment to determine if a proposal requires an environmental impact statement... environment; in such cases, an environmental assessment is not required and PADC will immediately begin to...

  11. 36 CFR 907.8 - Actions that normally require an EIS.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... CORPORATION ENVIRONMENTAL QUALITY § 907.8 Actions that normally require an EIS. PADC shall perform or have performed an environmental assessment to determine if a proposal requires an environmental impact statement... environment; in such cases, an environmental assessment is not required and PADC will immediately begin to...

  12. 75 FR 72784 - Helena National Forest; Montana; Blackfoot Travel Plan EIS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-26

    ... Forest Service Helena National Forest; Montana; Blackfoot Travel Plan EIS AGENCY: Forest Service, USDA. ACTION: Corrected Notice of Intent to prepare an Environmental Impact Statement for the Blackfoot Travel Plan. SUMMARY: This notice extends the comment period for the Blackfoot Travel Plan from November 30...

  13. 78 FR 20883 - Tonto National Forest; Arizona; Salt River Allotments Vegetative Management EIS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-08

    ...; ] DEPARTMENT OF AGRICULTURE Forest Service Tonto National Forest; Arizona; Salt River Allotments Vegetative... that it is extending the public comment period for the Salt River Allotments Vegetative Management... Availability of the Draft EIS (78 FR 12310) for more detailed information related to the Salt River...

  14. Evaluation of EIS alternatives by the science integration team, volume I.

    Treesearch

    Thomas M. Quigley; Kristine M. Lee; Sylvia J. Arbelbide

    1997-01-01

    The Evaluation of EIS Alternatives by the Science Integration Team describes the outcomes, interactions, effects, and consequences likely to result from implementing seven different management strategies on Forest Service (FS) and Bureau of Land Management (BLM) administered lands within the Interior Columbia Basin and portions of the Klamath and Great Basins. Two...

  15. 12 CFR 1815.108 - Actions that normally require an EIS.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... an Application will have a significant impact on the environment; in such cases, an environmental... TREASURY ENVIRONMENTAL QUALITY § 1815.108 Actions that normally require an EIS. (a) If necessary, the Fund shall perform or have performed an environmental assessment to determine if an Application, or...

  16. 77 FR 26275 - Bonneville Power Administration; Montana-to-Washington Transmission System Upgrade Project EIS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-03

    ... Environmental Impact Statement (EIS) and notice of floodplain and wetlands involvement. SUMMARY: BPA intends to... floodplain and wetlands environmental review requirements, BPA will prepare a floodplain and wetlands assessment to avoid or minimize potential harm to or within any affected floodplains and wetlands....

  17. 36 CFR 1010.8 - Actions that normally require an EIS.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... impact on the environment, an EA is not required, and the Trust will prepare or direct the preparation of... new building, if that activity has a significant effect on the human environment; (3) Proposals that... or actions may significantly affect the environment and therefore require an EIS are described in...

  18. 36 CFR 907.8 - Actions that normally require an EIS.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... generated by the proposal or action would represent a substantial increase over the traffic projections... Area or its environs; (3) Air quality in the Development Area and its environs would be substantially... CORPORATION ENVIRONMENTAL QUALITY § 907.8 Actions that normally require an EIS. PADC shall perform or...

  19. 7 CFR 520.7 - Preparation of an Environmental Impact Statement (EIS).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... significantly affecting the quality of the human environment; or, (2) Other major Federal actions significantly affecting the quality of the human environment. In the experience of ARS, an environmental impact statement... 7 Agriculture 6 2011-01-01 2011-01-01 false Preparation of an Environmental Impact Statement (EIS...

  20. Detection of Quorum Sensing Signal Molecules in Edwardsiella ictaluri Ei-151.

    PubMed

    Yang, Qian; Han, Yin; Tinh, Nguyen Thi Ngoc; Hien, Nguyen Thi; Bossier, Peter

    2012-12-01

    Edwardsiella ictaluri is a Gram-negative pathogenic bacterium in the family Enterobacteriaceae that causes enteric septicemia of catfish, which has become a significant problem in the aquaculture of striped catfish (Pangasianodon hypophthalmus) in Vietnam. In this study, a bacterium designated as Ei-151 was isolated from diseased striped catfish and proved to be virulent. Based on 16S rDNA sequencing and phenotypic tests, the pathogenic bacterium was identified as Edw. ictaluri. The presence of quorum sensing signal molecules in Edw. ictaluri Ei-151 was detected with different biosensor strains. The results showed that Ei-151 produced at least three kinds of acylated homoserine lactone (AHL) signal molecules as detected with the biosensor Agrobacterium tumefaciens KYC55, and the AHLs fingerprint was similar to that of Edw. tarda. During its entire growth, the levels of AHLs and autoinducer-2 produced by Ei-151 peaked at the stationary phase (OD600 1.8), which suggested that both of them may function at the stationary phase. No Cholerae autoinducer-1-like activity (including Edw. ictaluri LMG7860(T)) was detected.

  1. 76 FR 2881 - Fishlake National Forest; Utah; Oil and Gas Leasing EIS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-18

    ... Forest Service Fishlake National Forest; Utah; Oil and Gas Leasing EIS AGENCY: Forest Service, USDA. ACTION: Corrected Notice of Intent to prepare an environmental impact statement for the Oil and Gas... proposal to make lands administered by the FNF available for oil and gas leasing, and to determine what...

  2. Robust axonal regeneration occurs in the injured CAST/Ei mouse central nervous system

    PubMed Central

    Omura, Takao; Omura, Kumiko; Tedeschi, Andrea; Riva, Priscilla; Painter, Michio W; Rojas, Leticia; Martin, Joshua; Lisi, Véronique; Huebner, Eric A; Latremoliere, Alban; Yin, Yuqin; Barrett, Lee; Singh, Bhagat; Lee, Stella; Crisman, Tom; Gao, Fuying; Li, Songlin; Kapur, Kush; Geschwind, Daniel H; Kosik, Kenneth S; Coppola, Giovanni; He, Zhigang; Carmichael, S Thomas; Benowitz, Larry I; Costigan, Michael; Woolf, Clifford J

    2015-01-01

    SUMMARY Axon regeneration in the central nervous system (CNS) requires reactivating injured neurons’ intrinsic growth state and enabling growth in an inhibitory environment. Using an inbred mouse neuronal phenotypic screen, we find that CAST/Ei mouse adult dorsal root ganglion neurons extend axons more on CNS myelin than the other eight strains tested, especially when pre-injured. Injury-primed CAST/Ei neurons also regenerate markedly in the spinal cord and optic nerve more than those from C57BL/6 mice and show greater spouting following ischemic stroke. Heritability estimates indicate that extended growth in CAST/Ei neurons on myelin is genetically determined, and two whole-genome expression screens yield the Activin transcript Inhba as most correlated with this ability. Inhibition of Activin signaling in CAST/Ei mice diminishes their CNS regenerative capacity whereas its activation in C57BL/6 animals boosts regeneration. This screen demonstrates that mammalian CNS regeneration can occur and reveals a molecular pathway that contributes to this ability. PMID:26004914

  3. Using Energy Information Systems (EIS): A Guidebook for the U.S. Postal Service

    SciTech Connect

    Foster, Dale; Hough, Ben; Barbose, Galen; Golove, William; Goldman, Charles

    2004-10-11

    The U.S. Postal Service (Postal Service) recently installed Energy Information Systems (EIS) at 30 facilities in California. These systems integrate electric utility meter data acquisition hardware, software, and communication systems to collect, archive, analyze, and display whole-facility energy consumption data. At some point in the future, these systems could also be integrated with sub-meters that measure the electricity consumption of key end-use equipment. The purpose of this guidebook is to help Postal Service facility managers interpret and act upon energy data available from their EIS, translating the abundance of information these systems provide into knowledge that can be used to reduce energy use and costs. The guidebook first describes basic EIS capabilities and explains the data and reports that Postal Service EIS provide. It outlines a set of strategies for utilizing this information to improve operations and maintenance of building energy use equipment and for facilitating demand response. Finally, the guidebook offers suggestions on creating a routine for tracking and analyzing energy data and integrating this information into regular energy management activities.

  4. The Iterative Use of Single Case Research Designs to Advance the Science of EI/ECSE

    ERIC Educational Resources Information Center

    Barton, Erin E.; Ledford, Jennifer R.; Lane, Justin D.; Decker, Jessica; Germansky, Sara E.; Hemmeter, Mary Louise; Kaiser, Ann

    2016-01-01

    Research in early intervention/early childhood special education (EI/ECSE) is focused on identifying effective practices related to positive outcomes for young children with disabilities and their families. Individual responses to evidence-based practices are often variable, and non-responders are common. Single case research (SCR) might be…

  5. Recruitment and Retention of Qualified Early Intervention (EI) Personnel. Practice Brief. Winter 2011

    ERIC Educational Resources Information Center

    Muller, Eve

    2011-01-01

    The recruitment and retention of qualified early intervention (EI) personnel remains a challenge throughout many regions of the nation. In response to this challenge, states and localities are employing a range of innovative strategies. Based on examples drawn from around the country, including examples provided by the National Early Childhood…

  6. 75 FR 41452 - Withdrawal of the Environmental Impact Statement (EIS) Development Process for the Proposed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-16

    ... Department of the Army, Corps of Engineers Withdrawal of the Environmental Impact Statement (EIS) Development Process for the Proposed Beluga to Fairbanks (B2F) Natural Gas Transportation Pipeline AGENCY: U.S. Army... Environmental Impact Statement (DEIS) to address the potential impacts associated with the construction of the...

  7. 76 FR 29218 - Intent To Prepare an Environmental Impact Statement (EIS) for the Alaska Department of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-20

    ... Department of the Army, Corps of Engineers Intent To Prepare an Environmental Impact Statement (EIS) for the... Alaska District, U.S. Army Corps of Engineers (Corps) intends to prepare a Draft Environmental Impact...; socioeconomics; and secondary and cumulative impacts. 5. Other Environmental Review and Consultation Requirements...

  8. 77 FR 40144 - Adoption of the Environmental Impact Statement (EIS) and Participation in the Section 106...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-06

    ... Federal Railroad Administration Adoption of the Environmental Impact Statement (EIS) and Participation in... Administration (FRA), Department of Transportation (DOT). ACTION: Notice of adoption and recirculation of the...-20; Washington, DC 20590; Phone (202) 493-0398. DATES: Submit comments regarding adoption of the 2001...

  9. Recruitment and Retention of Qualified Early Intervention (EI) Personnel. Practice Brief. Winter 2011

    ERIC Educational Resources Information Center

    Muller, Eve

    2011-01-01

    The recruitment and retention of qualified early intervention (EI) personnel remains a challenge throughout many regions of the nation. In response to this challenge, states and localities are employing a range of innovative strategies. Based on examples drawn from around the country, including examples provided by the National Early Childhood…

  10. 78 FR 29120 - Notice of Intent (NOI) To Prepare an Environmental Impact Statement (EIS) for Proposed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-17

    ... of Intent (NOI) To Prepare an Environmental Impact Statement (EIS) for Proposed Establishment and... Airport, Portland, and Kingsley Field, Klamath Falls, OR AGENCY: Department of the Air Force; DOD. ACTION: Notice of Intent. SUMMARY: Pursuant to the National Environmental Policy Act (NEPA) of 1969, as...

  11. 78 FR 47048 - Notice of Availability of Final Environmental Impact Statement (Final EIS)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-02

    ... Federal Aviation Administration Notice of Availability of Final Environmental Impact Statement (Final EIS... accordance with the National Environmental Policy Act of 1969 (NEPA, 42 U.S.C. 4321 et seq.) and Council on Environmental Quality regulations (40 CFR Part 1500-1508), the Federal Aviation Administration (FAA) is...

  12. The EIS beamline at the seeded free-electron laser FERMI

    NASA Astrophysics Data System (ADS)

    Simoncig, A.; Mincigrucci, R.; Principi, E.; Bencivenga, F.; Calvi, A.; Foglia, L.; Kurdi, G.; Raimondi, L.; Manfredda, M.; Mahne, N.; Gobessi, R.; Gerusina, S.; Fava, C.; Zangrando, M.; Matruglio, A.; Dal Zilio, S.; Masciotti, V.; Masciovecchio, C.

    2017-05-01

    Among the fourth-generation light sources, the Italian free-electron laser (FEL) FERMI is the only one operating in the high-gain harmonic generation (HGHG) seeding mode. FERMI delivers pulses characterized by a quasi transform limited temporal structure, photon energies lying in the extreme ultra-violet (EUV) region, supreme transversal and longitudinal coherences, high peak brilliance, and full control of the polarization. Such state of the art performances recently opened the doors to a new class of time-resolved spectroscopies, difficult or even impossible to be performed using self-amplified spontaneous sources (SASE) light sources. FERMI is currently equipped with three operating beamlines opened to external users (DiProI, LDM and EIS), while two more are under commissioning (MagneDYN and TeraFERMI). Here, we present the recent highlights of the EIS (Elastic and Inelastic Scattering) beamline, which has been purposely designed to take full advantage from the coherence, the intensity, the harmonics content, and the temporal duration of the pulses. EIS is a flexible experimental facility for time-resolved EUV scattering experiments on condensed matter systems, consisting of two independent end-stations. The first one (EIS-TIMEX) aims to study materials in metastable and warm dense matter (WDM) conditions, while the second end-station (EIS-TIMER) is fully oriented to the extension of four-wave mixing (FWM) spectroscopies towards the EUV spectral regions, trying to reveal the behavior of matter in portions of the mesoscopic regime of exchanged momentum impossible to be probed using conventional light sources.

  13. How to Meet the Last OIE Expert Surveillance Panel Recommendations on Equine Influenza (EI) Vaccine Composition: A Review of the Process Required for the Recombinant Canarypox-Based EI Vaccine.

    PubMed

    Paillot, Romain; Rash, Nicola L; Garrett, Dion; Prowse-Davis, Leah; Montesso, Fernando; Cullinane, Ann; Lemaitre, Laurent; Thibault, Jean-Christophe; Wittreck, Sonia; Dancer, Agnes

    2016-11-25

    Vaccination is highly effective to prevent, control, and limit the impact of equine influenza (EI), a major respiratory disease of horses. However, EI vaccines should contain relevant equine influenza virus (EIV) strains for optimal protection. The OIE expert surveillance panel annually reviews EIV evolution and, since 2010, the use of Florida clade 1 and 2 sub-lineages representative vaccine strains is recommended. This report summarises the development process of a fully- updated recombinant canarypox-based EI vaccine in order to meet the last OIE recommendations, including the vaccine mode of action, production steps and schedule. The EI vaccine ProteqFlu contains 2 recombinant canarypox viruses expressing the haemagglutinin of the A/equine/Ohio/03 and A/equine/Richmond/1/07 isolates (Florida clade 1 and 2 sub-lineages, respectively). The updated EI vaccine was tested for efficacy against the representative Florida clade 2 EIV strain A/equine/Richmond/1/07 in the Welsh mountain pony model. Protective antibody response, clinical signs of disease and virus shedding were compared with unvaccinated control ponies. Significant protection was measured in vaccinated ponies, which supports the vaccine registration. The recombinant canarypox-based EI vaccine was the first fully updated EI vaccine available in the EU, which will help to minimise the increasing risk of vaccine breakdown due to constant EIV evolution through antigenic drift.

  14. How to Meet the Last OIE Expert Surveillance Panel Recommendations on Equine Influenza (EI) Vaccine Composition: A Review of the Process Required for the Recombinant Canarypox-Based EI Vaccine

    PubMed Central

    Paillot, Romain; Rash, Nicola L.; Garrett, Dion; Prowse-Davis, Leah; Montesso, Fernando; Cullinane, Ann; Lemaitre, Laurent; Thibault, Jean-Christophe; Wittreck, Sonia; Dancer, Agnes

    2016-01-01

    Vaccination is highly effective to prevent, control, and limit the impact of equine influenza (EI), a major respiratory disease of horses. However, EI vaccines should contain relevant equine influenza virus (EIV) strains for optimal protection. The OIE expert surveillance panel annually reviews EIV evolution and, since 2010, the use of Florida clade 1 and 2 sub-lineages representative vaccine strains is recommended. This report summarises the development process of a fully- updated recombinant canarypox-based EI vaccine in order to meet the last OIE recommendations, including the vaccine mode of action, production steps and schedule. The EI vaccine ProteqFlu contains 2 recombinant canarypox viruses expressing the haemagglutinin of the A/equine/Ohio/03 and A/equine/Richmond/1/07 isolates (Florida clade 1 and 2 sub-lineages, respectively). The updated EI vaccine was tested for efficacy against the representative Florida clade 2 EIV strain A/equine/Richmond/1/07 in the Welsh mountain pony model. Protective antibody response, clinical signs of disease and virus shedding were compared with unvaccinated control ponies. Significant protection was measured in vaccinated ponies, which supports the vaccine registration. The recombinant canarypox-based EI vaccine was the first fully updated EI vaccine available in the EU, which will help to minimise the increasing risk of vaccine breakdown due to constant EIV evolution through antigenic drift. PMID:27897990

  15. 77 FR 5566 - Notice of Availability of the Final EIS for the HB In-Situ Solution Mine Project, Eddy County...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-03

    ... Bureau of Land Management Notice of Availability of the Final EIS for the HB In-Situ Solution Mine... prepared a Final Environmental Impact Statement (Final EIS) for the HB In-Situ Solution Mine Project, and... Notice of Availability of the Final EIS in the Federal Register. ADDRESSES: Copies of the HB...

  16. Whole Genome Sequence of Two Wild-Derived Mus musculus domesticus Inbred Strains, LEWES/EiJ and ZALENDE/EiJ, with Different Diploid Numbers

    PubMed Central

    Morgan, Andrew P.; Didion, John P.; Doran, Anthony G.; Holt, James M.; McMillan, Leonard; Keane, Thomas M.; de Villena, Fernando Pardo-Manuel

    2016-01-01

    Wild-derived mouse inbred strains are becoming increasingly popular for complex traits analysis, evolutionary studies, and systems genetics. Here, we report the whole-genome sequencing of two wild-derived mouse inbred strains, LEWES/EiJ and ZALENDE/EiJ, of Mus musculus domesticus origin. These two inbred strains were selected based on their geographic origin, karyotype, and use in ongoing research. We generated 14× and 18× coverage sequence, respectively, and discovered over 1.1 million novel variants, most of which are private to one of these strains. This report expands the number of wild-derived inbred genomes in the Mus genus from six to eight. The sequence variation can be accessed via an online query tool; variant calls (VCF format) and alignments (BAM format) are available for download from a dedicated ftp site. Finally, the sequencing data have also been stored in a lossless, compressed, and indexed format using the multi-string Burrows-Wheeler transform. All data can be used without restriction. PMID:27765810

  17. Whole Genome Sequence of Two Wild-Derived Mus musculus domesticus Inbred Strains, LEWES/EiJ and ZALENDE/EiJ, with Different Diploid Numbers.

    PubMed

    Morgan, Andrew P; Didion, John P; Doran, Anthony G; Holt, James M; McMillan, Leonard; Keane, Thomas M; de Villena, Fernando Pardo-Manuel

    2016-12-07

    Wild-derived mouse inbred strains are becoming increasingly popular for complex traits analysis, evolutionary studies, and systems genetics. Here, we report the whole-genome sequencing of two wild-derived mouse inbred strains, LEWES/EiJ and ZALENDE/EiJ, of Mus musculus domesticus origin. These two inbred strains were selected based on their geographic origin, karyotype, and use in ongoing research. We generated 14× and 18× coverage sequence, respectively, and discovered over 1.1 million novel variants, most of which are private to one of these strains. This report expands the number of wild-derived inbred genomes in the Mus genus from six to eight. The sequence variation can be accessed via an online query tool; variant calls (VCF format) and alignments (BAM format) are available for download from a dedicated ftp site. Finally, the sequencing data have also been stored in a lossless, compressed, and indexed format using the multi-string Burrows-Wheeler transform. All data can be used without restriction. Copyright © 2016 Morgan et al.

  18. Comprehensive Summary and Analysis of Oral and Written Scoping Comments on the Hawaii Geothermal Project EIS (DOE Review Draft)

    SciTech Connect

    1992-09-18

    This report contains summaries of the oral and written comments received during the scoping process for the Hawaii Geothermal Project (HGP) Environmental Impact Statement (EIS). Oral comments were presented during public scoping meetings; written comments were solicited at the public scoping meetings and in the ''Advance Notice of Intent'' and ''Notice of Intent'' (published in the ''Federal Register'') to prepare the HGP EIS. This comprehensive summary of scoping inputs provides an overview of the issues that have been suggested for inclusion in the HGP EIS.

  19. Value of electrical impedance scanning (EIS) in the evaluation of BI-RADS III/IV/V-lesions.

    PubMed

    Diebold, Thomas; Jacobi, Volkmar; Scholz, Bernard; Hensel, Conny; Solbach, Christine; Kaufmann, Manfred; Viana, Fernando; Balzer, Joern; Peters, Jutta; Vogl, Thomas

    2005-02-01

    Two hundred and fifty-six (256) patients (72% preoperative, 28% pre-Mammotome) were prospectively examined with EIS using the TS 2000 (TransScan Research and Development Center, Israel; temporarily distributed by Siemens, Erlangen) with the "LOS"-software (level of suspicion). All exams were performed with the targeted scan probe, the observer knowing all clinical and imaging facts. The area of the lesions was examined with EIS at least with 5 single scans. The evaluation included a scaling of lesions from 1 (surely benign) up to 5 (highly suggestive for malignancy) as well as the additional notification of spots. Results of EIS were based upon the automatic scaling which is provided by the software and were compared with mammography and histology. Furthermore the influence of the histology, size of lesions, and presence/absence of spots on the EIS results were analyzed. Histology revealed benign results in 138 lesions and malignant results in 118 lesions (DCIS=61, ID-Ca=51, IL-Ca=5, mucinous Ca=1). Mammography as expected yielded high values with 91% sensitivity and 62% specificity. Overall sensitivity of EIS was 75.4%, specificity 42.03%, negative predictive value 66.7% and positive predictive value 52.7% (89 TP, 58 TN, 80 FP, 29 FN). EIS was false negative in 20 ID-Ca, 3 IL-Ca, 1 IDL-Ca, 4 DCIS, and 1 mucinous carcinoma. Sensitivity and specificity of EIS did not differ for the different histological differentiations neither for the degree of invasion. Also the additional notification of "spots" didn't show a correlation to malignancy. There were significant differences of the sensitivity of EIS regarding the tumor size. While EIS correctly diagnosed 85% of lesions <10 mm in size, only 64% of lesions >10 mm were detected. Most frequent lesion types for false positives were mastopathy (55/80 FP) and fibroadenoma (21/80 FP). Patient acceptance of EIS was perfect and there were no drop outs because of movement artifacts. In conclusion the "LOS"-software clearly

  20. Coupling RTD and EIS modelling to characterize operating non-uniformities on PEM cathodes

    NASA Astrophysics Data System (ADS)

    Deseure, Jonathan

    Large PEM cells will be used in future proton exchange membrane fuel cell (PEMFC) power plants and appropriate tools are therefore be needed to study their behaviour. One approach to understanding single cell behaviour involves using mathematical models. The numerous techniques used in this work to describe PEM electrode behaviour require different scientific disciplines: chemical engineering and electrochemistry. This study proposes combining residence time distribution (RTD) and electrochemical impedance spectroscopy (EIS). The investigation focuses on cathodic DC and AC responses where over-voltage is critical. Results demonstrate that although gas distribution does not cause additional loops on impedance diagrams, it is strongly related to both the shape and amplitude of these diagrams. The simulations have drawn attention to operating conditions that can threaten the life of the PEM cell: under these setting points EIS method is not sufficient to detect this risk.

  1. Energy information systems (EIS): Technology costs, benefit, and best practice uses

    SciTech Connect

    Granderson, Jessica; Lin, Guanjing; Piette, Mary Ann

    2013-11-26

    Energy information systems are the web-based software, data acquisition hardware, and communication systems used to store, analyze, and display building energy data. They often include analysis methods such as baselining, benchmarking, load profiling, and energy anomaly detection. This report documents a large-scale assessment of energy information system (EIS) uses, costs, and energy benefits, based on a series of focused case study investigations that are synthesized into generalizable findings. The overall objective is to provide organizational decision makers with the information they need to make informed choices as to whether or not to invest in an EIS--a promising technology that can enable up to 20 percent site energy savings, quick payback, and persistent low-energy performance when implemented as part of best-practice energy management programs.

  2. Development and Electrochemical Investigations of an EIS- (Electrolyte-Insulator-Semiconductor) based Biosensor for Cyanide Detection

    PubMed Central

    Turek, Monika; Ketterer, Lothar; Claβen, Melanie; Berndt, Heinz K.; Elbers, Gereon; Krüger, Peter; Keusgen, Michael; Schöning, Michael J.

    2007-01-01

    A cyanide biosensor based on a pH-sensitive p-doped electrolyte-insulator-semiconductor (EIS) structure with an immobilised enzyme (cyanidase) is realised at the laboratory scale. The immobilisation of the cyanidase is performed in two distinct steps: first, the covalent coupling of cyanidase to an N-hydroxysuccinimide- (NHS) activated Sepharose™ gel and then, the physical entrapment of NHS-activated Sepharose™ with the immobilised cyanidase in a dialysis membrane onto the EIS structure. The immobilisation of the cyanidase to the NHS-activated Sepharose™ is studied by means of gel electrophoresis measurements and investigations using an ammonia- (NH3) selective electrode. For the electrochemical characterisation of the cyanide biosensor, capacitance/voltage and constant capacitance measurements, respectively, have been carried out. A differential measurement procedure is presented to evaluate the cyanide concentration-dependent biosensor signals.

  3. Schistosoma mansoni experimental infection in Mus spretus (SPRET/EiJ strain) mice

    PubMed Central

    Pérez del Villar, Luis; Vicente, Belén; Galindo-Villardón, Purificación; Castellanos, Andrés; Pérez-Losada, Jesús; Muro, Antonio

    2013-01-01

    Most Schistosoma mansoni experimental infections are developed in several inbred strains of Mus musculus as definitive host. In contrast, Mus spretus is unexplored in Schistosoma infection studies. Mus spretus provides a high variation of immunological phenotypes being an invaluable tool for genetic studies and gene mapping. The aim of this study is to characterize hematological and immunological responses against Schistosoma mansoni infection in Mus spretus (SPRET/EiJ strain) vs. Mus musculus (CD1 strain) mice. Nine weeks after cercarial exposure, animals were perfused and the parasite burden was assessed. The parasitological data suggests that SPRET/EiJ mice tolerate higher parasite loads compared to CD1 strain. In addition, hematological parameters measured in Mus spretus group showed a significant increase in granulocytes population in early stages of infection compared to the CD1 cohort. Meanwhile, CD1 presented higher levels of lymphocytes and IgG1 in the late stages of S. mansoni experimental infection. PMID:23985166

  4. The EIS-TIMER beamline: transient grating spectroscopy at FERMI (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Svetina, Cristian

    2016-09-01

    FERMI, the Italian Free Electron Laser user facility, provides VUV/soft x-ray photons pulses with unprecedented high brilliance and coherence. The unique design of EIS-TIMER is conceived to exploit such kind of non-linear coherent experiments to probe collective vibrational and electronic properties of matter at the nanoscale. After the proof of principle experiment successfully carried out at the DiProI beamline employing a simplified and compact setup (mini-TIMER), the EIS-TIMER beamline has been installed and commissioned. The beamlines employs 24 mirrors and three photon beams in order to create a wide set of transient grating able to reach Q vectors so far impossible to probe. In the presentation the scientific case, the commissioning results as well as the future development of the beamline will be shown. The future project nano-TIMER will be described in detail with particular attention to it's unique optical scheme mainly composed by diffraction gratings.

  5. Emotional intelligence (EI) as a predictor of depression status in older adults.

    PubMed

    Lloyd, Sandra J; Malek-Ahmadi, Michael; Barclay, Kathleen; Fernandez, Miguel R; Chartrand, Max Stanley

    2012-01-01

    Underdeveloped recognition systems or predictors for negative consequences related to depression in the older adult put this population at a significant risk for suicide, medical illness, and poor health status. Research concerning strategies for predicting depression in the older adult population has not until recently focused on the possibility of measuring one's EI as a potential predictive factor. To address an aspect of this neglect, the present quantitative correlational study explored to what extent the total Emotional Quotient (EQ) scale score of EI predicted depression. Two self-report measures were utilized: the Geriatric Depression Scale-Short (GDS-Short), and the Bar-On Emotional Quotient Inventory:Short (EQ-i:S). A purposive sample of 128 men and women (ages 65 and older) were recruited from local recreation centers and independent living facilities. To determine the extent to which EQ-i:S scaled score predicted depression, multiple logistic regression analysis was carried out. After accounting for age, education, and anti-depressant use, EQ-i:S scaled score had a statistically significant effect OR=0.94 (0.91, 0.97), p<0.001. This result indicated that for every 1-point increase in EQ-i:S scaled score, the risk of having depression decreased by 6%. The results indicated that increased EI has a beneficial effect in terms of current depression status. Future longitudinal research in examining EI as a predictor for depression in the older adult population is needed to substantiate and expand upon these findings. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  6. Response of the Antarctic Stratosphere to Warm Pool EI Nino Events in the GEOS CCM

    NASA Technical Reports Server (NTRS)

    Hurwitz, Margaret M.; Song, In-Sun; Oman, Luke D.; Newman, Paul A.; Molod, Andrea M.; Frith, Stacey M.; Nielsen, J. Eric

    2011-01-01

    A new type of EI Nino event has been identified in the last decade. During "warm pool" EI Nino (WPEN) events, sea surface temperatures (SSTs) in the central equatorial Pacific are warmer than average. The EI Nino signal propagates poleward and upward as large-scale atmospheric waves, causing unusual weather patterns and warming the polar stratosphere. In austral summer, observations show that the Antarctic lower stratosphere is several degrees (K) warmer during WPEN events than during the neutral phase of EI Nino/Southern Oscillation (ENSO). Furthermore, the stratospheric response to WPEN events depends of the direction of tropical stratospheric winds: the Antarctic warming is largest when WPEN events are coincident with westward winds in the tropical lower and middle stratosphere i.e., the westward phase of the quasi-biennial oscillation (QBO). Westward winds are associated with enhanced convection in the subtropics, and with increased poleward wave activity. In this paper, a new formulation of the Goddard Earth Observing System Chemistry-Climate Model, Version 2 (GEOS V2 CCM) is used to substantiate the observed stratospheric response to WPEN events. One simulation is driven by SSTs typical of a WPEN event, while another simulation is driven by ENSO neutral SSTs; both represent a present-day climate. Differences between the two simulations can be directly attributed to the anomalous WPEN SSTs. During WPEN events, relative to ENSO neutral, the model simulates the observed increase in poleward planetary wave activity in the South Pacific during austral spring, as well as the relative warming of the Antarctic lower stratosphere in austral summer. However, the modeled response to WPEN does not depend on the phase of the QBO. The modeled tropical wind oscillation does not extend far enough into the lower stratosphere and upper troposphere, likely explaining the model's insensitivity to the phase of the QBO during WPEN events.

  7. Temperature And Density Analysis Of A Coronal Loop Observed By Eis And Aia

    NASA Astrophysics Data System (ADS)

    Plowman, Joseph; Martens, P.; Kankelborg, C.; Ritchie, M.; Scott, J.; Sharma, R.

    2012-05-01

    We present a combined DEM and density-sensitive line ratio analysis of a loop observed simultaneously by EIS and AIA. The DEMs are calculated using a fast new method which we also describe. The temperature and density profiles of the loop are compared to and isolated from those of the surrounding material, and these properties are fit to an analytic strand heating model developed by Martens (2010). Supported by an AIA subcontract to Montana State University.

  8. Evaluation of the oil spill risk analysis as presented in St. George Basin Sale 89 EIS

    SciTech Connect

    Not Available

    1985-05-31

    The report describes and evaluates the current approach to the oil-spill risk analysis as conducted for St. George Basin Sale 89. An oil spill trajectory analysis (OTSA) model was developed for the U.S. Minerals Management Service to calculate the risk of oil spills damaging environmentally sensitive resources. The purpose of the report is to review the Minerals Management Service oil-spill risk analysis as presented in the Lease Sale 89 EIS.

  9. PLASMA DIAGNOSTICS OF AN EIT WAVE OBSERVED BY HINODE/EIS AND SDO/AIA

    SciTech Connect

    Veronig, A. M.; Kienreich, I. W.; Muhr, N.; Temmer, M.; Goemoery, P.; Vrsnak, B.; Warren, H. P.

    2011-12-10

    We present plasma diagnostics of an Extreme-Ultraviolet Imaging Telescope (EIT) wave observed with high cadence in Hinode/Extreme-Ultraviolet Imaging Spectrometer (EIS) sit-and-stare spectroscopy and Solar Dynamics Observatory/Atmospheric Imaging Assembly imagery obtained during the HOP-180 observing campaign on 2011 February 16. At the propagating EIT wave front, we observe downward plasma flows in the EIS Fe XII, Fe XIII, and Fe XVI spectral lines (log T Almost-Equal-To 6.1-6.4) with line-of-sight (LOS) velocities up to 20 km s{sup -1}. These redshifts are followed by blueshifts with upward velocities up to -5 km s{sup -1} indicating relaxation of the plasma behind the wave front. During the wave evolution, the downward velocity pulse steepens from a few km s{sup -1} up to 20 km s{sup -1} and subsequently decays, correlated with the relative changes of the line intensities. The expected increase of the plasma densities at the EIT wave front estimated from the observed intensity increase lies within the noise level of our density diagnostics from EIS Fe XIII 202/203 A line ratios. No significant LOS plasma motions are observed in the He II line, suggesting that the wave pulse was not strong enough to perturb the underlying chromosphere. This is consistent with the finding that no H{alpha} Moreton wave was associated with the event. The EIT wave propagating along the EIS slit reveals a strong deceleration of a Almost-Equal-To -540 m s{sup -2} and a start velocity of v{sub 0} Almost-Equal-To 590 km s{sup -1}. These findings are consistent with the passage of a coronal fast-mode MHD wave, pushing the plasma downward and compressing it at the coronal base.

  10. Acetylcholinesterase Inhibitors (AChEI's) for the treatment of visual hallucinations in schizophrenia: a case report

    PubMed Central

    2010-01-01

    Background Visual hallucinations are commonly seen in various neurological and psychiatric disorders including schizophrenia. Current models of visual processing and studies in diseases including Parkinsons Disease and Lewy Body Dementia propose that Acetylcholine (Ach) plays a pivotal role in our ability to accurately interpret visual stimuli. Depletion of Ach is thought to be associated with visual hallucination generation. AchEI's have been used in the targeted treatment of visual hallucinations in dementia and Parkinson's Disease patients. In Schizophrenia, it is thought that a similar Ach depletion leads to visual hallucinations and may provide a target for drug treatment Case Presentation We present a case of a patient with Schizophrenia presenting with treatment resistant and significantly distressing visual hallucinations. After optimising treatment for schizophrenia we used Rivastigmine, an AchEI, as an adjunct to treat her symptoms successfully. Conclusions This case is the first to illustrate this novel use of an AchEI in the targeted treatment of visual hallucinations in a patient with Schizophrenia. Targeted therapy of this kind can be considered in challenging cases although more evidence is required in this field. PMID:20822516

  11. Coordinated Observations of AR 11726 by Hinode/EIS and EUNIS-2013

    NASA Astrophysics Data System (ADS)

    Ancheta, A. J.; Daw, A. N.; Brosius, J. W.

    2016-12-01

    The Extreme-Ultraviolet Normal-Incidence Spectrograph (EUNIS) sounding rocket payload was flown on 2013 April 23 with two independent channels covering the 300-370 A and 525-635 A wavebands. EUNIS-2013 observed two targets on the solar disk that included quiet sun, active regions, a flare, and a micro-flare. The active region AR 11726 was co-observed with the EUV Imaging Spectrometer (EIS) on Hinode. The radiometric response of EUNIS is measured in the laboratory using a NIST-calibrated photodiode and hollow cathode discharge lamp. A density- and temperature- insensitive line intensity ratio technique can be used to derive an in-flight calibration update of Hinode/EIS. Measurements of EIS emission lines with respect to EUNIS lines, including Fe X to Fe XII and Si X, provide a comparison between the calibrations of the two instruments. The radiometric calibration of EUNIS-2013 is also validated using the same insensitive ratio technique with emission lines such as Mg VIII, Fe XI, Fe XVI, and Si IX.

  12. High spatial resolution impedance measurement of EIS sensors for light addressable cell adhesion monitoring.

    PubMed

    Yu, Hui; Wang, Jun; Liu, Qingjun; Zhang, Wei; Cai, Hua; Wang, Ping

    2011-02-15

    In this paper, impedance measurement of electrolyte-insulator-semiconductor (EIS) structure with high spatial resolution was proposed to monitor cell adhesion. The light addressing ability of this work overcomes the geometrical restrict of cell culture on conventional impedance detection devices such as interdigitated electrode (IDE) and electric cell-substrate impedance sensing (ECIS). Instead of studying cells on predetermined sites of IDE and ECIS, cells cultured anywhere on EIS sensor surface can be addressed and selected as target cells. Principle and primary models for high resolution impedance detection were described and tested by experiments. The EIS sensor was investigated in terms of its intrinsic characteristics, like impedance behavior, voltage characteristic, frequency dependency and photovoltaic effect. Optimized working condition was studied for cell experiments. Cell adhesion under treatment of 0.1% Triton X-100 was monitored using rat kidney cells as the source. Results showed good sensitivity (10% change of impedance) and resolution (40 μm) for cell adhesion impedance detection and suggested this work should be suitable for monitoring cell impedance. Further improvements on sensitivity, spatial resolution were discussed as well as the further applications for single cell monitoring and cell adhesion imaging. Copyright © 2010 Elsevier B.V. All rights reserved.

  13. Frequency Regulation and Oscillation Damping Contributions of Variable-Speed Wind Generators in the U.S. Eastern Interconnection (EI)

    SciTech Connect

    Liu, Yong; Gracia, Jose R,; King, Jr, Thomas J.; Liu, Yilu

    2014-05-16

    The U.S. Eastern Interconnection (EI) is one of the largest electric power grids in the world and is expected to have difficulties in dealing with frequency regulation and oscillation damping issues caused by the increasing wind power. On the other side, variable-speed wind generators can actively engage in frequency regulation or oscillation damping with supplementary control loops. This paper creates a 5% wind power penetration simulation scenario based on the 16 000-bus EI system dynamic model and developed the user-defined wind electrical control model in PSS (R) E that incorporates additional frequency regulation and oscillation damping control loops. We evaluated the potential contributions of variable-speed wind generations to the EI system frequency regulation and oscillation damping, and simulation results demonstrate that current and future penetrations of wind power are promising in the EI system frequency regulation and oscillation damping.

  14. 75 FR 74128 - Rescinding the Notice of Intent for an Environmental Impact Statement (EIS): Harrison and Stone...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-30

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF TRANSPORTATION Federal Highway Administration Rescinding the Notice of Intent for an Environmental Impact Statement (EIS): Harrison and Stone Counties, MS AGENCY: Federal Highway Administration, DOT. ACTION...

  15. Frequency Regulation and Oscillation Damping Contributions of Variable-Speed Wind Generators in the U.S. Eastern Interconnection (EI)

    DOE PAGES

    Liu, Yong; Gracia, Jose R,; King, Jr, Thomas J.; ...

    2014-05-16

    The U.S. Eastern Interconnection (EI) is one of the largest electric power grids in the world and is expected to have difficulties in dealing with frequency regulation and oscillation damping issues caused by the increasing wind power. On the other side, variable-speed wind generators can actively engage in frequency regulation or oscillation damping with supplementary control loops. This paper creates a 5% wind power penetration simulation scenario based on the 16 000-bus EI system dynamic model and developed the user-defined wind electrical control model in PSS (R) E that incorporates additional frequency regulation and oscillation damping control loops. We evaluatedmore » the potential contributions of variable-speed wind generations to the EI system frequency regulation and oscillation damping, and simulation results demonstrate that current and future penetrations of wind power are promising in the EI system frequency regulation and oscillation damping.« less

  16. A correlation between EIS and salt spray proof tests for the corrosion resistance of conversion coated aluminum alloys

    SciTech Connect

    Buchheit, R.G.; Martinez, M.A.; Cunningham, M.; Jensen, H.; Kendig, M.W.

    1996-09-01

    In this study, 33 different conversion coatings were applied to 5 different Al alloy substrates. Salt spray exposure testing and EIS (electrochemical impedance spectroscopy) were conducted for comparison. A relation was developed.

  17. 77 FR 52108 - Notice of Withdrawal of the Notice of Intent To Prepare an Environmental Impact Statement (EIS...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-28

    ... Impact Statement (EIS) for the Proposed Sheep Mountain Parkway Multimodal Transportation Project, Clark..., Chief, Environmental Services, Nevada Department of Transportation, 1263 South Stewart Street, Carson... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION...

  18. FLARE FOOTPOINT REGIONS AND A SURGE OBSERVED BY HINODE/EIS, RHESSI, AND SDO/AIA

    SciTech Connect

    Doschek, G. A.; Warren, H. P.; Dennis, B. R.; Reep, J. W.; Caspi, A.

    2015-11-01

    The Extreme-ultraviolet Imaging Spectrometer (EIS) on the Hinode spacecraft observed flare footpoint regions coincident with a surge for an M3.7 flare observed on 2011 September 25 at N12 E33 in active region 11302. The flare was observed in spectral lines of O vi, Fe x, Fe xii, Fe xiv, Fe xv, Fe xvi, Fe xvii, Fe xxiii, and Fe xxiv. The EIS observations were made coincident with hard X-ray bursts observed by RHESSI. Overlays of the RHESSI images on the EIS raster images at different wavelengths show a spatial coincidence of features in the RHESSI images with the EIS upflow and downflow regions, as well as loop-top or near-loop-top regions. A complex array of phenomena were observed, including multiple evaporation regions and the surge, which was also observed by the Solar Dynamics Observatory/Atmospheric Imaging Assembly telescopes. The slit of the EIS spectrometer covered several flare footpoint regions from which evaporative upflows in Fe xxiii and Fe xxiv lines were observed with Doppler speeds greater than 500 km s{sup −1}. For ions such as Fe xv both evaporative outflows (∼200 km s{sup −1}) and downflows (∼30–50 km s{sup −1}) were observed. Nonthermal motions from 120 to 300 km s{sup −1} were measured in flare lines. In the surge, Doppler speeds are found from about 0 to over 250 km s{sup −1} in lines from ions such as Fe xiv. The nonthermal motions could be due to multiple sources slightly Doppler-shifted from each other or turbulence in the evaporating plasma. We estimate the energetics of the hard X-ray burst and obtain a total flare energy in accelerated electrons of ≥7 × 10{sup 28} erg. This is a lower limit because only an upper limit can be determined for the low-energy cutoff to the electron spectrum. We find that detailed modeling of this event would require a multithreaded model owing to its complexity.

  19. Flare Footpoint Regions and a Surge Observed by Hindode/EIS, RHESSI, and SDO/AIA

    NASA Astrophysics Data System (ADS)

    Doschek, G. A.; Warren, H. P.; Dennis, B. R.; Reep, J. W.; Caspi, A.

    2015-11-01

    The Extreme-ultraviolet Imaging Spectrometer (EIS) on the Hinode spacecraft observed flare footpoint regions coincident with a surge for an M3.7 flare observed on 2011 September 25 at N12 E33 in active region 11302. The flare was observed in spectral lines of O vi, Fe x, Fe xii, Fe xiv, Fe xv, Fe xvi, Fe xvii, Fe xxiii, and Fe xxiv. The EIS observations were made coincident with hard X-ray bursts observed by RHESSI. Overlays of the RHESSI images on the EIS raster images at different wavelengths show a spatial coincidence of features in the RHESSI images with the EIS upflow and downflow regions, as well as loop-top or near-loop-top regions. A complex array of phenomena were observed, including multiple evaporation regions and the surge, which was also observed by the Solar Dynamics Observatory/Atmospheric Imaging Assembly telescopes. The slit of the EIS spectrometer covered several flare footpoint regions from which evaporative upflows in Fe xxiii and Fe xxiv lines were observed with Doppler speeds greater than 500 km s-1. For ions such as Fe xv both evaporative outflows (˜200 km s-1) and downflows (˜30-50 km s-1) were observed. Nonthermal motions from 120 to 300 km s-1 were measured in flare lines. In the surge, Doppler speeds are found from about 0 to over 250 km s-1 in lines from ions such as Fe xiv. The nonthermal motions could be due to multiple sources slightly Doppler-shifted from each other or turbulence in the evaporating plasma. We estimate the energetics of the hard X-ray burst and obtain a total flare energy in accelerated electrons of ≥7 × 1028 erg. This is a lower limit because only an upper limit can be determined for the low-energy cutoff to the electron spectrum. We find that detailed modeling of this event would require a multithreaded model owing to its complexity.

  20. Acetylcholinesterase Inhibitors (AChEI's) for the treatment of visual hallucinations in schizophrenia: A review of the literature

    PubMed Central

    2010-01-01

    Background Visual hallucinations occur in various neurological diseases, but are most prominent in Lewy body dementia, Parkinson's disease and schizophrenia. The lifetime prevalence of visual hallucinations in patients with schizophrenia is much more common than conventionally thought and ranges from 24% to 72%. Cortical acetylcholine (ACh) depletion has been associated with visual hallucinations; the level of depletion being related directly to the severity of the symptoms. Current understanding of neurobiological visual processing and research in diseases with reduced cholinergic function, suggests that AChEI's may prove beneficial in treating visual hallucinations. This offers the potential for targeted drug therapy of clinically symptomatic visual hallucinations in patients with schizophrenia using acetylcholinesterase inhibition. Methods A systematic review was carried out investigating the evidence for the effects of AChEI's in treating visual hallucinations in Schizophrenia. Results No evidence was found relating to the specific role of AChEI's in treating visual hallucinations in this patient group. Discussion Given the use of AChEI's in targeted, symptom specific treatment in other neuropsychiatric disorders, it is surprising to find no related literature in schizophrenia patients. The use of AChEI's in schizophrenia has investigated effects on cognition primarily with non cognitive effects measured more broadly. Conclusions We would suggest that more focused research into the effects of AChEI's on positive symptoms of schizophrenia, specifically visual hallucinations, is needed. PMID:20822517

  1. Erwinia amylovora novel plasmid pEI70: complete sequence, biogeography, and role in aggressiveness in the fire blight phytopathogen.

    PubMed

    Llop, Pablo; Cabrefiga, Jordi; Smits, Theo H M; Dreo, Tanja; Barbé, Silvia; Pulawska, Joanna; Bultreys, Alain; Blom, Jochen; Duffy, Brion; Montesinos, Emilio; López, María M

    2011-01-01

    Comparative genomics of several strains of Erwinia amylovora, a plant pathogenic bacterium causal agent of fire blight disease, revealed that its diversity is primarily attributable to the flexible genome comprised of plasmids. We recently identified and sequenced in full a novel 65.8 kb plasmid, called pEI70. Annotation revealed a lack of known virulence-related genes, but found evidence for a unique integrative conjugative element related to that of other plant and human pathogens. Comparative analyses using BLASTN showed that pEI70 is almost entirely included in plasmid pEB102 from E. billingiae, an epiphytic Erwinia of pome fruits, with sequence identities superior to 98%. A duplex PCR assay was developed to survey the prevalence of plasmid pEI70 and also that of pEA29, which had previously been described in several E. amylovora strains. Plasmid pEI70 was found widely dispersed across Europe with frequencies of 5-92%, but it was absent in E. amylovora analyzed populations from outside of Europe. Restriction analysis and hybridization demonstrated that this plasmid was identical in at least 13 strains. Curing E. amylovora strains of pEI70 reduced their aggressiveness on pear, and introducing pEI70 into low-aggressiveness strains lacking this plasmid increased symptoms development in this host. Discovery of this novel plasmid offers new insights into the biogeography, evolution and virulence determinants in E. amylovora.

  2. Academic Medicine Education Institute (AM·EI): Transforming the Educational Culture of Health Professionals.

    PubMed

    Goh, Sok Hong; Tan, Kok Hian; Kamei, Robert K; Koo, Wen Hsin; Cook, Sandy

    2015-05-01

    The Academic Medicine Education Institute (AM∙EI), jointly established by Duke-NUS Graduate Medical School (Duke-NUS) and Singapore Healthcare Services (SingHealth), is a newly formed health professions education academy designed to cultivate best education practices and create a community of health professions educators. To achieve the aims of AM∙EI, the needs of SingHealth educators have to be understood. Therefore, this study was carried out to assess educators' perceptions towards the current education climate and their academic needs. A 28-item questionnaire consisting of free-response, Likert-type and ranking questions was developed. The questionnaire was electronically distributed to 200 medical and nursing educators, and made available to attendees of the 2012 Singhealth Duke-NUS Scientific Congress through hardcopies. A total of 150 completed questionnaires were received (94 from electronic survey and 56 from Congress). Five themes emerged from the analysis of responses to free-response questions: 1) faculty development, 2) development of a community of educators, 3) recognition for educational efforts, 4) institutional support, and 5) better communication about SingHealth educational activities. Respondents were in highest agreement with the statements (rating of 3.7 out of 5): "The SingHealth education programmes are high quality", "New learning or teaching methods are welcomed in this institution/hospital", and "An academic appointment is important to me". The competencies that respondents felt to be the most important were facilitating discussions, presentation skills, and providing feedback (respective means = 5.1, 5, 5 of 7). This needs assessment provided us with important insights regarding SingHealth medical educators' perceptions of their education environment and established key priorities for the AM∙EI's programming efforts.

  3. Heating and dynamics of two flare loop systems observed by AIA and EIS

    SciTech Connect

    Li, Y.; Ding, M. D.; Qiu, J.

    2014-02-01

    We investigate heating and evolution of flare loops in a C4.7 two-ribbon flare on 2011 February 13. From Solar Dynamics Observatory/Atmospheric Imaging Assembly (AIA) imaging observations, we can identify two sets of loops. Hinode/EUV Imaging Spectrometer (EIS) spectroscopic observations reveal blueshifts at the feet of both sets of loops. The evolution and dynamics of the two sets are quite different. The first set of loops exhibits blueshifts for about 25 minutes followed by redshifts, while the second set shows stronger blueshifts, which are maintained for about one hour. The UV 1600 observation by AIA also shows that the feet of the second set of loops brighten twice. These suggest that continuous heating may be present in the second set of loops. We use spatially resolved UV light curves to infer heating rates in the few tens of individual loops comprising the two loop systems. With these heating rates, we then compute plasma evolution in these loops with the 'enthalpy-based thermal evolution of loops' model. The results show that, for the first set of loops, the synthetic EUV light curves from the model compare favorably with the observed light curves in six AIA channels and eight EIS spectral lines, and the computed mean enthalpy flow velocities also agree with the Doppler shift measurements by EIS. For the second set of loops modeled with twice-heating, there are some discrepancies between modeled and observed EUV light curves in low-temperature bands, and the model does not fully produce the prolonged blueshift signatures as observed. We discuss possible causes for the discrepancies.

  4. Analyzing sediment impacts for the Glen Canyon Long-term Experimental and Management Plan EIS

    NASA Astrophysics Data System (ADS)

    Russell, K.; Huang, V.; Varyu, D.; Greimann, B. P.; O'Connor, B. L.

    2013-12-01

    The Department of the Interior is currently evaluating alternatives in the Glen Canyon Dam Long-term Experimental and Management Plan (LTEMP) Environmental Impact Statement (EIS). The purpose of the EIS to evaluate dam operations and identify management actions and experimental options that will provide a framework for adaptively managing operations of Glen Canyon Dam over the next 15 to 20 years. Sediment and sandbars along the Colorado River are important downstream resources in Grand Canyon National Park. Sediment is one of the resources being analyzed for impacts in Marble and Grand Canyon. Since 1963, Glen Canyon Dam has regulated the flow in the Colorado River by decreasing the magnitude of annual flood flows and increasing the magnitude of base flows, and has nearly eliminated main-channel sand supply from the upper Colorado River Basin. These changes disrupted the natural ability of the river to build and maintain sandbars. Grand Canyon sandbars provide camping beaches for river runners and hikers, generate habitat for native fish and vegetation, and supply sediment to protect archaeological resources. In order to measure the impacts of the different alternatives on the sediment resource, several different models are being utilized. A sand budget numerical model that tracks the storage and transport of sand in the Colorado River below Glen Canyon Dam developed by the USGS is utilized. The model uses empirically based rating curves for specific particle sizes. The decision criteria for the high flow experiment environmental assessment is applied to the sand budget model as well as other flow changes incorporated in the alternatives. An empirically based sandbar volume model was also developed for the LTEMP EIS process to address the sandbar resource impacts. Based on the model results, performance criteria have been established to allow for comparisons between the alternatives. The criteria include the changes in the sand mass balance of the system, the

  5. The Europa Imaging System (EIS): Investigating Europa's geology, ice shell, and current activity

    NASA Astrophysics Data System (ADS)

    Turtle, Elizabeth; Thomas, Nicolas; Fletcher, Leigh; Hayes, Alexander; Ernst, Carolyn; Collins, Geoffrey; Hansen, Candice; Kirk, Randolph L.; Nimmo, Francis; McEwen, Alfred; Hurford, Terry; Barr Mlinar, Amy; Quick, Lynnae; Patterson, Wes; Soderblom, Jason

    2016-07-01

    NASA's Europa Mission, planned for launch in 2022, will perform more than 40 flybys of Europa with altitudes at closest approach as low as 25 km. The instrument payload includes the Europa Imaging System (EIS), a camera suite designed to transform our understanding of Europa through global decameter-scale coverage, topographic and color mapping, and unprecedented sub- meter-scale imaging. EIS combines narrow-angle and wide-angle cameras to address these science goals: • Constrain the formation processes of surface features by characterizing endogenic geologic structures, surface units, global cross-cutting relationships, and relationships to Europa's subsurface structure and potential near-surface water. • Search for evidence of recent or current activity, including potential plumes. • Characterize the ice shell by constraining its thickness and correlating surface features with subsurface structures detected by ice penetrating radar. • Characterize scientifically compelling landing sites and hazards by determining the nature of the surface at scales relevant to a potential lander. EIS Narrow-angle Camera (NAC): The NAC, with a 2.3°° x 1.2°° field of view (FOV) and a 10-μμrad instantaneous FOV (IFOV), achieves 0.5-m pixel scale over a 2-km-wide swath from 50-km altitude. A 2-axis gimbal enables independent targeting, allowing very high-resolution stereo imaging to generate digital topographic models (DTMs) with 4-m spatial scale and 0.5-m vertical precision over the 2-km swath from 50-km altitude. The gimbal also makes near-global (>95%) mapping of Europa possible at ≤50-m pixel scale, as well as regional stereo imaging. The NAC will also perform high-phase-angle observations to search for potential plumes. EIS Wide-angle Camera (WAC): The WAC has a 48°° x 24°° FOV, with a 218-μμrad IFOV, and is designed to acquire pushbroom stereo swaths along flyby ground-tracks. From an altitude of 50 km, the WAC achieves 11-m pixel scale over a 44-km

  6. The Application of EIS and PIV Methods to the Measurement of Aerated Flow

    NASA Astrophysics Data System (ADS)

    Fejfarová, M.

    2013-04-01

    The paper describes measurements in the aerated water medium using modern methods PIV (Particle Image Velocimetry) and EIS (Electrical Impedance Spectrometry), which are applied in the Laboratory of Water Management Research (LVV) of the Department of Water Structures (UVST) at the Faculty of Civil Engineering (FAST) of Brno University of Technology (VUT). Measurements of the water medium were carried out for three different aeration intensities at special experimental workplaces. The experiment was focused on the capability of the methods to monitor the air content in the water.

  7. Shape-based Particle Separation via Elasto-Inertia Pinched Flow Fractionation (eiPFF)

    NASA Astrophysics Data System (ADS)

    Lu, Xinyu; Xuan, Xiangchun

    2015-11-01

    We report in this talk a continuous-flow shape-based separation of spherical and peanut-shaped rigid particles of equal volume via elasto-inertial pinched flow fractionation (eiPFF). This separation exploits the shape-dependence of the cross-stream particle migration induced by the elaso-inertial lift force in viscoelastic fluids. The parametric effects on this separation are systematically investigated in terms of dimensionless numbers. It is found that this separation is strongly affected by the Reynolds number, Weissenberg number and channel aspect ratio. Interestingly, the elasto-inertial deflection of peanut particles can be either greater or smaller than that of spherical particles.

  8. Constraining the Coronal Heating Mechanism Using Data from AIA, EIS, and Hi-C

    NASA Astrophysics Data System (ADS)

    Martens, P. C.; Plowman, J.; Kankelborg, C. C.

    2013-12-01

    We have developed an ultra-fast DEM inversion code that computes over 1000 DEMs/sec for a sample active region observed by the Atmospheric Imaging Assembly (AIA) on SDO, and achieves reduced chi-squareds of order unity with no negative emission in all but a few test cases (Plowman et al. 2013 ApJ). Applying the code to simultaneous Hinode/EIS data we find good agreement, and of course much less uncertainty in the EIS DEMs. For the short interval that we have Hi-C data we can estimate filling factors from those. We are using this new tool to constrain the still elusive mechanism of coronal heating. In one approach we use simultaneous AIA and EIS data of loops that are mostly north-south oriented, and hence do not require a broad EIS raster. We derive the density in these loops from density sensitive line pairs, and the DEMs from AIA data. In many cases the background subtracted DEMs indicate a single temperature at many points in the loop, and hence we have a measurement of both density and temperature along a good part of the loop. Combining these results with analytical (Martens 2010) models for loop heating we find that the heating is concentrated at the footpoints, consistent with, for example, Ohmic heating, but inconsistent with several other popular models for coronal heating. In the second approach we use the remarkable speed of our DEM inversion code to measure the occurrence of heating events in Active Regions (AR). We have determined that with the cadence of about ten seconds of the combined AIA channels, our code can detect heating events roughly down to the energy of nano-flares, about 10^24 ergs. By analyzing the DEMs sequences per pixel of target ARs we derive statistics on the heating events, in particular their frequency and energy distribution. Therefrom we can determine whether the energy input from nano-flares and more energetic events provides the energy required to sustain the AR corona.

  9. Detecting Corrosion Resistance of Coated Steel Rebars by Electrochemical Technique (eis)

    NASA Astrophysics Data System (ADS)

    Ryou, J.; Shah, S.

    Electrochemical impedance spectroscopy (EIS) is one of the electrochemical techniques used in materials science. The present measurements are used to evaluate the corrosion resistance of new types of coated steel rebar used in reinforced concrete. In this study, Si-based coating materials are used and evaluated, because adding Si to metals and alloys, including steel, generally increases their corrosion, oxidation, and erosion resistance. The result suggests that electrochemical impedance spectroscopy may be useful for monitoring corrosion activity on coated steel rebars. Based upon impedance changes, it appears that the silicon powder coating bonds well to the steel, and that the coating has a good performance.

  10. Supplement Analysis for Yakima/Klickitat Fisheries Project, Boone Pond Acclimation Site (DOE/EIS-0169-SA-08)

    SciTech Connect

    Smith, Patricia R.

    2004-04-07

    Yakima/Klickitat Fisheries Project – Under the Monitoring and Evaluation Program (M&E), the coho acclimation research task would be modified to include a new site located in the upper Yakima south of Cle Elum, WA. The Yakima Fisheries Project Final Environmental Impact Statement (YFP EIS) (USDOE/BPA 1996) analyzed impacts of undertaking fishery research and mitigation activities in the Yakima River Basin. The EIS focused on the impacts of construction, operation and maintenance of anadromous fish production facilities in order to conduct research designed to increase knowledge of supplementation techniques. Spring chinook were the priority species analyzed in the EIS, however, Coho feasibility studies, potential harvest benefits, and predation impacts for returning natural production of Coho salmon to the Yakima River Basin were also evaluated. Subsequent Supplement Analyses (SA’s) have analyzed the potential impacts of research activities relating to this experimental design program (DOE/EIS-0169-SA-01 through SA-07). The purpose of this Supplement Analysis (SA) is to determine if a Supplemental EIS (SEIS) is needed to analyze the changes proposed in the Yakima Klickitat Fisheries Project (YKFP) Coho Program feasibility studies.

  11. Functional characterization of EI24-induced autophagy in the degradation of RING-domain E3 ligases

    PubMed Central

    Devkota, Sushil; Jeong, Hyobin; Kim, Yunmi; Ali, Muhammad; Roh, Jae-il; Hwang, Daehee; Lee, Han-Woong

    2016-01-01

    ABSTRACT Historically, the ubiquitin-proteasome system (UPS) and autophagy pathways were believed to be independent; however, recent data indicate that these pathways engage in crosstalk. To date, the players mediating this crosstalk have been elusive. Here, we show experimentally that EI24 (EI24, autophagy associated transmembrane protein), a key component of basal macroautophagy/autophagy, degrades 14 physiologically important E3 ligases with a RING (really interesting new gene) domain, whereas 5 other ligases were not degraded. Based on the degradation results, we built a statistical model that predicts the RING E3 ligases targeted by EI24 using partial least squares discriminant analysis. Of 381 RING E3 ligases examined computationally, our model predicted 161 EI24 targets. Those targets are primarily involved in transcription, proteolysis, cellular bioenergetics, and apoptosis and regulated by TP53 and MTOR signaling. Collectively, our work demonstrates that EI24 is an essential player in UPS-autophagy crosstalk via degradation of RING E3 ligases. These results indicate a paradigm shift regarding the fate of E3 ligases. PMID:27541728

  12. Susceptibility of the wild-derived inbred CAST/Ei mouse to infection by orthopoxviruses analyzed by live bioluminescence imaging

    SciTech Connect

    Americo, Jeffrey L.; Sood, Cindy L.; Cotter, Catherine A.; Vogel, Jodi L.; Kristie, Thomas M.; Moss, Bernard Earl, Patricia L.

    2014-01-20

    Classical inbred mice are extensively used for virus research. However, we recently found that some wild-derived inbred mouse strains are more susceptible than classical strains to monkeypox virus. Experiments described here indicated that the 50% lethal dose of vaccinia virus (VACV) and cowpox virus (CPXV) were two logs lower in wild-derived inbred CAST/Ei mice than classical inbred BALB/c mice, whereas there was little difference in the susceptibility of the mouse strains to herpes simplex virus. Live bioluminescence imaging was used to follow spread of pathogenic and attenuated VACV strains and CPXV virus from nasal passages to organs in the chest and abdomen of CAST/Ei mice. Luminescence increased first in the head and then simultaneously in the chest and abdomen in a dose-dependent manner. The spreading kinetics was more rapid with VACV than CPXV although the peak photon flux was similar. These data suggest advantages of CAST/Ei mice for orthopoxvirus studies. - Highlights: • Wild-derived inbred CAST/Ei mice are susceptible to vaccinia virus and cowpox virus. • Morbidity and mortality from orthopoxviruses are greater in CAST/Ei than BALB/c mice. • Morbidity and mortality from herpes simplex virus type 1 are similar in both mice. • Imaging shows virus spread from nose to lungs, abdominal organs and brain. • Vaccinia virus spreads more rapidly than cowpox virus.

  13. Results from the magnetic electron ion spectrometer (MagEIS) instruments aboard the Van Allen Probes spacecraft

    NASA Astrophysics Data System (ADS)

    Fennell, Joseph; O'Brien, Paul; Roeder, James; Reeves, Geoffrey; Claudepierre, Seth; Clemmons, James; Spence, Harlan; Blake, Bernard

    The Magnetic Electron Ion Spectrometer (MagEIS) instruments aboard the Van Allen Probes Spacecraft (formerly RBSP) measure electrons and ions in the Earth's inner and outer radiation belts. The MagEIS instruments are part of the Energetic Particle, Composition, and Thermal Plasma Suite (ECT), which also includes the Relativistic Electron Proton Telescope (REPT) and the Helium Oxygen Proton Electron (HOPE) analyzer. MagEIS consists of four magnetic electron spectrometers aboard each of the two Van Allen Probes spacecraft that measure the differential fluxes, energies, and angular distributions of electrons from 20 keV to 4 MeV. The MagEIS suite also contains a silicon-detector telescope that measures the differential fluxes, energies, and angular distributions of protons from 60 keV to 20 MeV, and helium and oxygen ions above a hundred keV/AMU. We briefly describe the instrument design and measurement technique and present a set of results from the MagEIS observations, including ultra-low frequency (ULF) modulations of energetic electron flux, and observations of electron flux enhancements associated with the recent BARREL x-ray observations.

  14. Evaluation of inorganic zinc-rich primers using Electrochemical Impedance Spectroscopy (EIS)

    NASA Technical Reports Server (NTRS)

    Calle, Luz M.

    1993-01-01

    This investigation explores the use of Electrochemical Impedance Spectroscopy (EIS) in combination with beach exposure as a short term method for analyzing the performance of twenty-one zinc-rich primers. The twenty-one zinc-rich primers were: Carboline CZ-11, Ameron Devoe-Marine Catha-Coat 304, Briner V-65, Ameron D-21-9, Sherwin Williams Zinc Clad II, Carboline CZ-D7, Ameron D-4, Dupont Ganicin 347WB, Porter TQ-4374H, Inorganic Coatings IC-531, Subox Galvanox IV, Southern Coatings Chemtec 600, Glidden Glidzinc 5530, Byco SP-101, Tnemec 90E-75, Devoe Catha-Coat 302H, Glidden Glidzinc 5536, Koppers 701, Ameron D-21-5, Coronado 935-152, and Subox Galvanoz V. Data were also collected on galvanized steel for comparison purposes. A library of Bode magnitude plots was generated for each coating including curves for the initial time and after each week of atmospheric exposure as Beach Corrosion Test Site near the Space Shuttle launch pad at the Kennedy Space Center for up to three weeks. An examination of the variation of the Bode magnitude plots with atmospheric exposure revealed no clearly identifiable trend at this point that could distinguish between the good and the poor coatings. The test will be continued by including EIS measurements after six months and one year of atmospheric exposure.

  15. Lessons learnt from post EIS evaluations of national road schemes in Ireland

    SciTech Connect

    King, E.A.; O'Malley, V.P.

    2012-01-15

    The Irish National Roads Authority (NRA) recently completed over twenty post environmental impact assessment evaluations of noise chapters prepared as part of Environmental Impact Statements (EISs) for new national road schemes in Ireland. The study focused on a range of issues including a review of noise monitoring procedures, noise prediction methodologies and an assessment of the effectiveness of noise mitigation measures currently in use on national road schemes. This review was carried out taking cognisance of best international practices for noise assessment and methodologies used to mitigate road traffic noise. The primary focus of the study was to assess the actual noise impacts of national road scheme developments and to revise, where necessary, methodologies recommended in the current NRA guidance document describing the treatment of noise on national road schemes. This paper presents a summary of the study and identifies a number of key areas that should be considered prior to the development of future guidance documents. - Highlights: Black-Right-Pointing-Pointer Presents a post-EIS evaluation of noise assessments for national roads in Ireland. Black-Right-Pointing-Pointer The effectiveness of some noise mitigation measures is critically evaluated. Black-Right-Pointing-Pointer Issues related to the current EIS noise assessment methodologies are discussed. Black-Right-Pointing-Pointer Implications for alterations to the NRA noise guidelines.

  16. Evaluation of inorganic zinc-rich primers using Electrochemical Impedance Spectroscopy (EIS)

    NASA Technical Reports Server (NTRS)

    Calle, Luz M.

    1993-01-01

    This investigation explores the use of Electrochemical Impedance Spectroscopy (EIS) in combination with beach exposure as a short term method for analyzing the performance of twenty-one zinc-rich primers. The twenty-one zinc-rich primers were: Carboline CZ-11, Ameron Devoe-Marine Catha-Coat 304, Briner V-65, Ameron D-21-9, Sherwin Williams Zinc Clad II, Carboline CZ-D7, Ameron D-4, Dupont Ganicin 347WB, Porter TQ-4374H, Inorganic Coatings IC-531, Subox Galvanox IV, Southern Coatings Chemtec 600, Glidden Glidzinc 5530, Byco SP-101, Tnemec 90E-75, Devoe Catha-Coat 302H, Glidden Glidzinc 5536, Koppers 701, Ameron D-21-5, Coronado 935-152, and Subox Galvanoz V. Data were also collected on galvanized steel for comparison purposes. A library of Bode magnitude plots was generated for each coating including curves for the initial time and after each week of atmospheric exposure as Beach Corrosion Test Site near the Space Shuttle launch pad at the Kennedy Space Center for up to three weeks. An examination of the variation of the Bode magnitude plots with atmospheric exposure revealed no clearly identifiable trend at this point that could distinguish between the good and the poor coatings. The test will be continued by including EIS measurements after six months and one year of atmospheric exposure.

  17. [Investigations on leishmaniases at the E.I. Martsinovsky Institute of Medical Parasitology and Tropical Medicine].

    PubMed

    Kellina, O I; Strelkova, M V

    2010-01-01

    The paper assesses the investigations on leishmaniases at the E.I. Martsinovsky Institute of Medical Parasitology and Tropical Medicine in 1920 to 2009. The analysis includes papers on biology, ecology, taxonomy, and experimental transmission of the agents of leishmaniases via the bites of sand flies, the principle in the control of zoonotic cutaneous leishmaniasis (ZCL) during the agricultural development of extensive territories in the Karshin steppe, on quantitative approaches in the epidemiology of ZCL, a search for Russian effective medicaments to treat patients with this disease and the development of criteria for selecting L. major strains for individual and mass vaccinations against ZCL, the revision of Leishmania circulating in great gerbil populations, and the description of the new species L. turanica, an important parasite for L. major persistence from one transmission season to the next. The first investigations on leishmaniasis were made by Prof. E.I. Martsinovsky, the founder and the first director of the Institute in the early 20th century.

  18. Analysis of cyanolipids from Sapindaceae seed oils by gas chromatography-EI-mass spectrometry.

    PubMed

    Tava, Aldo; Avato, Pinarosa

    2014-04-01

    As a continuation of our investigation on unusual lipids, in the present work we describe a method based on GC-FID and GC-EI-MS to analyze the molecular composition of intact cyanolipids (CL) from selected Sapindaceae plants. We applied our method to the study of CL of type I (1-cyano-2-hydroxymethyl-prop-2-en-1-ol-diester) from Paullinia cupana var. sorbilis and Allophylus dregeanus and CL type III (1-cyano-2-hydroxymethyl-prop-1-en-3-ol-diester) from A. natalensis and Nephelium lappaceum. Our analytical approach allowed us to obtain useful mass spectra to identify individual isomeric molecular species composing the CL mixtures and resulted in the very sensitive detection and identification of minor CL. Defined CL mass spectra resulted in suitable detection of these phytochemicals in complex plant oil mixtures containing acylglycerols. To the best of our knowledge GC-EI-MS spectra of cyanolipids have never been reported before. Moreover, this study improved previous knowledge of the lipid chemistry of Sapindaceae plants.

  19. Facts and artefacts regarding correlation between skin electrical impedance spectroscopy (EIS) and blood glucose

    NASA Astrophysics Data System (ADS)

    Ollmar, Stig; Nicander, Ingrid; Åberg, Peter; Bolinder, Jan

    2013-04-01

    Earlier observations on possible co-variation between skin EIS and blood glucose prompted us to map and include other factors at play in the predictive model. Skin pH would be one such factor. A cohort of 20 diabetics was investigated, taking around 30 measurements spread over each of two different days 2-21 days apart. Each measurement comprises skin EIT in the frequency range 1kHz to 2.5MHz, skin pH, and immediately evaluated blood samples. There is a co-variation for some, but not all, test persons. The relationship gets stronger on the group level by adding pH-information, but is still poor or non-existent for some test persons. Non-invasive EIS measurements on skin is influenced by skin hydration, blood glucose, skin pH, body location, season, environmental factors, and variables not yet understood. Since impedance related parameters are used to estimate skin hydration, users of such devices should be aware that skin pH may influence as much as the water content of the stratum corneum.

  20. Propagating waves in polar coronal holes as seen by SUMER & EIS

    NASA Astrophysics Data System (ADS)

    Banerjee, D.; Teriaca, L.; Gupta, G. R.; Imada, S.; Stenborg, G.; Solanki, S. K.

    2009-06-01

    Context: To study the dynamics of coronal holes and the role of waves in the acceleration of the solar wind, spectral observations were performed over polar coronal hole regions with the SUMER spectrometer on SoHO and the EIS spectrometer on Hinode. Aims: Using these observations, we aim to detect the presence of propagating waves in the corona and to study their properties. Methods: The observations analysed here consist of SUMER spectra of the Ne viii 770 Å line (T = 0.6 MK) and EIS slot images in the Fe xii 195 Å line (T = 1.3 MK). Using the wavelet technique, we study line radiance oscillations at different heights from the limb in the polar coronal hole regions. Results: We detect the presence of long period oscillations with periods of 10 to 30 min in polar coronal holes. The oscillations have an amplitude of a few percent in radiance and are not detectable in line-of-sight velocity. From the time distance maps we find evidence for propagating velocities from 75 km s-1 (Ne viii) to 125 km s-1 (Fe xii). These velocities are subsonic and roughly in the same ratio as the respective sound speeds. Conclusions: We interpret the observed propagating oscillations in terms of slow magneto-acoustic waves. These waves can be important for the acceleration of the fast solar wind.

  1. Biochemical characterization of a nitrogen-type phosphotransferase system reveals that enzyme EI(Ntr) integrates carbon and nitrogen signaling in Sinorhizobium meliloti.

    PubMed

    Goodwin, Reed A; Gage, Daniel J

    2014-05-01

    In Sinorhizobium meliloti, catabolite repression is influenced by a noncanonical nitrogen-type phosphotransferase system (PTS(Ntr)). In this PTS(Ntr), the protein HPr is phosphorylated on histidine-22 by the enzyme EI(Ntr) and the flux of phosphate through this residue onto downstream proteins leads to an increase in succinate-mediated catabolite repression (SMCR). In order to explore the molecular determinants of HPr phosphorylation by EI(Ntr), both proteins were purified and the activity of EI(Ntr) was measured. Experimentally determined kinetic parameters of EI(Ntr) activity were significantly slower than those determined for the carbohydrate-type EI in Escherichia coli. Enzymatic assays showed that glutamine, a signal of nitrogen availability in many Gram-negative bacteria, strongly inhibits EI(Ntr). Binding experiments using the isolated GAF domain of EI(Ntr) (EIGAF) showed that it is the domain responsible for detection of glutamine. EI(Ntr) activity was not affected by α-ketoglutarate, and no binding between the EIGAF and α-ketoglutarate could be detected. These data suggest that in S. melilloti, EI(Ntr) phosphorylation of HPr is regulated by signals from both carbon metabolism (phosphoenolpyruvate) and nitrogen metabolism (glutamine).

  2. Sensitivity of GC-EI/MS, GC-EI/MS/MS, LC-ESI/MS/MS, LC-Ag(+) CIS/MS/MS, and GC-ESI/MS/MS for analysis of anabolic steroids in doping control.

    PubMed

    Cha, Eunju; Kim, Sohee; Kim, Ho Jun; Lee, Kang Mi; Kim, Ki Hun; Kwon, Oh-Seung; Lee, Jaeick

    2015-01-01

    This study compared the sensitivity of various separation and ionization methods, including gas chromatography with an electron ionization source (GC-EI), liquid chromatography with an electrospray ionization source (LC-ESI), and liquid chromatography with a silver ion coordination ion spray source (LC-Ag(+) CIS), coupled to a mass spectrometer (MS) for steroid analysis. Chromatographic conditions, mass spectrometric transitions, and ion source parameters were optimized. The majority of steroids in GC-EI/MS/MS and LC-Ag(+) CIS/MS/MS analysis showed higher sensitivities than those obtained with other analytical methods. The limits of detection (LODs) of 65 steroids by GC-EI/MS/MS, 68 steroids by LC-Ag(+) CIS/MS/MS, 56 steroids by GC-EI/MS, 54 steroids by LC-ESI/MS/MS, and 27 steroids by GC-ESI/MS/MS were below cut-off value of 2.0 ng/mL. LODs of steroids that formed protonated ions in LC-ESI/MS/MS analysis were all lower than the cut-off value. Several steroids such as unconjugated C3-hydroxyl with C17-hydroxyl structure showed higher sensitivities in GC-EI/MS/MS analysis relative to those obtained using the LC-based methods. The steroids containing 4, 9, 11-triene structures showed relatively poor sensitivities in GC-EI/MS and GC-ESI/MS/MS analysis. The results of this study provide information that may be useful for selecting suitable analytical methods for confirmatory analysis of steroids.

  3. Identification of an interaction between EI and a histidine kinase-response regulator hybrid protein in Gluconobacter oxydans.

    PubMed

    Li, Shan; Ma, Yushu; Wei, Dongzhi

    2016-02-05

    Gluconobacter oxydans may contain an incomplete phosphoenolpyruvate: carbohydrate phosphotransferase system consisting of three components--EI, HPr and EIIA, while the function of individual members of the system remains unknown. In this research, a specific interaction between EI and a histidine kinase-response regulator hybrid protein was screened by yeast two-hybrid assay, and the interaction was further identified with GST pull-down assay and bimolecular fluorescence complementation assay in vitro and in vivo, respectively. As the histidine kinase-response regulator hybrid protein serves as a member of two-component system in G. oxydans, its interaction with EI implied that PTS may play certain roles in bacteria under stress.

  4. Photoelectric photometry of the RS CVn binary EI Eridani = HD 26337

    NASA Technical Reports Server (NTRS)

    Hooten, J. T.; Strassmeier, K. G.; Hall, D. S.; Barksdale, W. S., Jr.; Bertoglio, A.

    1989-01-01

    Differential UBV(RI)sub KC and UBVRI photometry of the RS CVn binary EI Eridani obtained during December 1987 and January 1988 at fourteen different observatories is presented. A combined visual bandpass light curve, corrected for systematic errors of different observatories, utilizes the photometric period of 1,945 days to produce useful results. The analysis shows the visual light curve to have twin maxima, separated by about 0.4 phase, and a full amplitude of approximately 0.06 mag for the period of observation, a smaller amplitude than reported in the past. The decrease in amplitude may be due to a decrease or homogenization of spot coverage. To fit the asymmetrical light curve, a starspot model would have to employ at least two spotted regions separated in longitude.

  5. Electrochemical Polishing Applications and EIS of a Novel Choline Chloride-Based Ionic Liquid

    SciTech Connect

    Wixtrom, Alex I.; Buhler, Jessica E.; Reece, Charles E.; Abdel-Fattah, Tarek M.

    2013-06-01

    Minimal surface roughness is a critical feature for high-field superconducting radio frequency (SRF) cavities used to engineer particle accelerators. Current methods for polishing Niobium cavities typically utilize solutions containing a mixture of concentrated sulfuric and hydrofluoric acid. Polishing processes such as these are effective, yet there are many hazards and costs associated with the use (and safe disposal) of the concentrated acid solutions. An alternative method for electrochemical polishing of the cavities was explored using a novel ionic liquid solution containing choline chloride. Potentiostatic electrochemical impedance spectroscopy (EIS) was used to analyze the ionic polishing solution. Final surface roughness of the Nb was found to be comparable to that of the acid-polishing method, as assessed by atomic force microscopy (AFM). This indicates that ionic liquid-based electrochemical polishing of Nb is a viable replacement for acid-based methods for preparation of SRF cavities.

  6. EIS observations of Doppler shifts in the structure of on-disk plumes

    NASA Astrophysics Data System (ADS)

    Fu, H.; Xia, L.; Li, B.; JIAO, F.; Mou, C.

    2013-12-01

    The contribution of plumes to the solar wind has been subject to hot debate in the past decades. The EUV Imaging Spectrometer (EIS) on board Hinode provides a unique means to deduce outflow speeds at coronal heights via direct Doppler shift measurements of coronal emission lines. Such direct Doppler shift measurements were not possible with previous spectrometer. We measure the outflow speed at coronal heights in several on-disk long-duration plumes, which are located in coronal holes and show significant blue shifts throughout the entire observational period. In one particular case, a plume is measured 4 hours apart. The deduced outflow speeds are consistent, suggesting that the flows are quasi-steady. Furthermore, we provide an outflow speed profile along the plumes, finding that the speed corrected for the Line-of-Sight effect reads 10 km/s at 1.01 Rsun, 15 km/s at 1.03 Rsun, and 25 km/s at 1.05 Rsun. This clear signature of steady acceleration, combined with the fact that there is no clear blueshift at the base of plumes (Hassler et al. 1999; Wilhelm et al.2000), provides an important constraint on plume models. At these heights, EIS also deduced a density of 10^8.1 cm^-3, resulting a proton flux of 5.5 x 10^9 cm^-2 s^-1 scaled to 1AU, which is an order of magnitude higher than necessary for the proton input to a typical fast solar wind if a radial expansion is assumed. This suggests that, coronal hole plumes may be an important source of the fast solar wind, but they do experience substantial lateral expansion and/or mass exchange with neighboring inter-plume plasmas.

  7. Measurements of outflow velocities in on-disk plumes from EIS/Hinode observations

    SciTech Connect

    Fu, Hui; Xia, Lidong; Li, Bo; Huang, Zhenghua; Jiao, Fangran; Mou, Chaozhou

    2014-10-20

    The contribution of plumes to the solar wind has been subject to hot debate in the past decades. The EUV Imaging Spectrometer (EIS) on board Hinode provides a unique means to deduce outflow velocities at coronal heights via direct Doppler shift measurements of coronal emission lines. Such direct Doppler shift measurements were not possible with previous spectrometers. We measure the outflow velocity at coronal heights in several on-disk long-duration plumes, which are located in coronal holes (CHs) and show significant blueshifts throughout the entire observational period. In one case, a plume is measured four hours apart. The deduced outflow velocities are consistent, suggesting that the flows are quasi-steady. Furthermore, we provide an outflow velocity profile along the plumes, finding that the velocity corrected for the line-of-sight effect can reach 10 km s{sup –1} at 1.02 R {sub ☉}, 15 km s{sup –1} at 1.03 R {sub ☉}, and 25 km s{sup –1} at 1.05 R {sub ☉}. This clear signature of steady acceleration, combined with the fact that there is no significant blueshift at the base of plumes, provides an important constraint on plume models. At the height of 1.03 R {sub ☉}, EIS also deduced a density of 1.3 × 10{sup 8} cm{sup –3}, resulting in a proton flux of about 4.2 × 10{sup 9} cm{sup –2} s{sup –1} scaled to 1 AU, which is an order of magnitude higher than the proton input to a typical solar wind if a radial expansion is assumed. This suggests that CH plumes may be an important source of the solar wind.

  8. Role of EIS in Materials and Coatings Selection for NASA's Launch Facilities

    NASA Technical Reports Server (NTRS)

    Calle, Luz Marina

    2004-01-01

    Corrosion studies began at NASA's John F. Kennedy Space Center (KSC) in 1966, during the Gemini/Apollo Programs, with the evaluation of long-term anti-corrosion coatings for carbon steel structures. NASAIKSC's Atmospheric Exposure Test Site was established at that time on the beach near the launch pad. In the years that followed, numerous studies at the site have identified materials, coatings, and maintenance procedures for launch hardware and equipment exposed to the highly corrosive environment at the launch pad. The atmosphere at the launch pad is highly corrosive due to the proximity of the Atlantic Ocean, high heat from rocket exhaust, and since the introduction of the Space Shuttle, the acidic combustion products of the Solid Rocket Boosters (SRBs). Currently, NASAIKSC maintains about $2 billion worth of unique equipment and facilities, not including the orbiters, each valued at about $1.8 billion. Among the items: two launch complexes, two crawler transporters, three mobile launch platforms, and specialized testing equipment. Atmospheric exposure provides very valuable data but it takes a long time and relies on human visual inspection. NASA Technical Standard for Protective Coatings requires 18 months of good performance at the Atmospheric Exposure Test Site for preliminary approval and continued good performance for 5 years for final approval of a coating system. The use of electrochemical impedance spectroscopy (EIS) was introduced at KSC in 1989 as a supplement to the traditional dc electrochemical techniques and atmospheric exposure studies. This paper presents and overview of several projects in which EIS was used in order to select materials and coatings to be used at NASA's launch facilities [1-2].

  9. Measurements of Outflow Velocities in on-disk Plumes from EIS/Hinode Observations

    NASA Astrophysics Data System (ADS)

    Fu, Hui; Xia, Lidong; Li, Bo; Huang, Zhenghua; Jiao, Fangran; Mou, Chaozhou

    2014-10-01

    The contribution of plumes to the solar wind has been subject to hot debate in the past decades. The EUV Imaging Spectrometer (EIS) on board Hinode provides a unique means to deduce outflow velocities at coronal heights via direct Doppler shift measurements of coronal emission lines. Such direct Doppler shift measurements were not possible with previous spectrometers. We measure the outflow velocity at coronal heights in several on-disk long-duration plumes, which are located in coronal holes (CHs) and show significant blueshifts throughout the entire observational period. In one case, a plume is measured four hours apart. The deduced outflow velocities are consistent, suggesting that the flows are quasi-steady. Furthermore, we provide an outflow velocity profile along the plumes, finding that the velocity corrected for the line-of-sight effect can reach 10 km s-1 at 1.02 R ⊙, 15 km s-1 at 1.03 R ⊙, and 25 km s-1 at 1.05 R ⊙. This clear signature of steady acceleration, combined with the fact that there is no significant blueshift at the base of plumes, provides an important constraint on plume models. At the height of 1.03 R ⊙, EIS also deduced a density of 1.3 × 108 cm-3, resulting in a proton flux of about 4.2 × 109 cm-2 s-1 scaled to 1 AU, which is an order of magnitude higher than the proton input to a typical solar wind if a radial expansion is assumed. This suggests that CH plumes may be an important source of the solar wind.

  10. The Impact of Engineering Integrated Science (EIS) Curricula on First-Year Technical High School Students' Attitudes toward Science and Perceptions of Engineering

    ERIC Educational Resources Information Center

    Nam, Younkyeong; Lee, Sun-Ju; Paik, Seoung-Hey

    2016-01-01

    This study investigated how engineering integrated science (EIS) curricula affect first-year technical high school students' attitudes toward science and perceptions of engineering. The effect of the EIS participation period on students' attitudes toward science was also investigated via experimental study design. Two engineering integrated…

  11. The Impact of Engineering Integrated Science (EIS) Curricula on First-Year Technical High School Students' Attitudes toward Science and Perceptions of Engineering

    ERIC Educational Resources Information Center

    Nam, Younkyeong; Lee, Sun-Ju; Paik, Seoung-Hey

    2016-01-01

    This study investigated how engineering integrated science (EIS) curricula affect first-year technical high school students' attitudes toward science and perceptions of engineering. The effect of the EIS participation period on students' attitudes toward science was also investigated via experimental study design. Two engineering integrated…

  12. 32 CFR Appendix C to Part 989 - Procedures for Holding Public Hearings on Draft Environmental Impact Statements (EIS)

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... submit (in writing or by return call) their intention to participate, with an indication of which... statements. A3.2.3.6. A suggestion that speakers submit statements of considerable length in writing. A3.2.3.7. A summary of the proposed action. A3.2.3.8. The location where the draft EIS and any appendices...

  13. 78 FR 17653 - Upper Great Plains Wind Energy Draft Programmatic Environmental Impact Statement (DOE/EIS-0408)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-22

    ... Wind Energy Draft Programmatic Environmental Impact Statement (DOE/EIS-0408) AGENCIES: Western Area... Service (Service), have, as joint lead agencies, prepared the Upper Great Plains Wind Energy Draft... wind energy development within Western's Upper Great Plains Customer Service Region (UGP Region), which...

  14. Electrochemical impedance spectroscopy (EIS) as a tool for measuring corrosion of polymer-coated fasteners used in treated wood

    Treesearch

    Samuel L. Zelinka; Lorraine Ortiz-Candelaria; Donald S. Stone; Douglas R. Rammer

    2009-01-01

    Currently, many of the polymer-coated fasteners on the market are designed for improved corrosion performance in treated wood; yet, there is no way to evaluate their corrosion performance. In this study, a common technique for measuring the corrosion performance of polymer-coated metals, electrochemical impedance spectroscopy (EIS), was used to evaluate commercial...

  15. 32 CFR Appendix C to Part 989 - Procedures for Holding Public Hearings on Draft Environmental Impact Statements (EIS)

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Environmental Impact Statements (EIS) C Appendix C to Part 989 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE ENVIRONMENTAL PROTECTION ENVIRONMENTAL IMPACT ANALYSIS PROCESS (EIAP) Pt. 989, App. C Appendix C to Part 989—Procedures for Holding Public Hearings on Draft Environmental Impact...

  16. 32 CFR Appendix C to Part 989 - Procedures for Holding Public Hearings on Draft Environmental Impact Statements (EIS)

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Environmental Impact Statements (EIS) C Appendix C to Part 989 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE ENVIRONMENTAL PROTECTION ENVIRONMENTAL IMPACT ANALYSIS PROCESS (EIAP) Pt. 989, App. C Appendix C to Part 989—Procedures for Holding Public Hearings on Draft Environmental Impact...

  17. 77 FR 37092 - Notice of Withdrawal of the Notice of Intent To Prepare an Environmental Impact Statement (EIS...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-20

    ... the Notice of Intent To Prepare an Environmental Impact Statement (EIS) for the Improvements to... Administration: Abdelmoez Abdalla, Environmental Program Manager, Federal Highway Administration, 705 N. Plaza... the Nevada Department of Transportation (NDOT): Mr. Steve M. Cooke, P.E., Chief, Environmental...

  18. 7 CFR 1940.313 - Actions that normally require the preparation of an Environmental Impact Statement (EIS).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Environmental Impact Statement (EIS). 1940.313 Section 1940.313 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE (CONTINUED) PROGRAM REGULATIONS (CONTINUED) GENERAL...

  19. The Europa Imaging System (EIS), a Camera Suite to investigate Europa's Geology, Ice Shell, and Potential for Current Activity

    NASA Astrophysics Data System (ADS)

    Turtle, E. P.; McEwen, A. S.; Osterman, S. N.; Boldt, J. D.; Strohbehn, K.; EIS Science Team

    2016-10-01

    EIS NAC and WAC use identical rad-hard rapid-readout 4k × 2k CMOS detectors for imaging during close (≤25 km) fast ( 4.5 km/s) Europa flybys. NAC achieves 0.5 m/pixel over a 2-km swath from 50 km, and WAC provides context pushbroom stereo imaging.

  20. 75 FR 26739 - Notice of Intent To Prepare an Environmental Impact Statement (EIS) for Airfield Operations at...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-12

    ... Environmental Impact Statement (EIS) for Airfield Operations at Naval Air Station (NAS) Key West, FL and To... Boulevard, Key West, Florida. 2. Thursday, May 27, 2010, Tennessee Williams Theater at Florida Keys... consecutive sessions from 3 p.m. to 5 p.m. and from 6 p.m. to 8 p.m. The meetings will be an open house...

  1. Application of nano-FIA-Direct-EI-MS to determine diethylene glycol in produced formation water discharges and seawater samples.

    PubMed

    Cappiello, Achille; Famiglini, Giorgio; Palma, Pierangela; Pierini, Elisabetta; Trufelli, Helga; Maggi, Chiara; Manfra, Loredana; Mannozzi, Michela

    2007-09-01

    Diethylene glycol (DEG) is extensively used on offshore gas platforms to prevent the hydrate formation during the gas-water separation process and to inhibit corrosion events. This chemical might enter in the marine environment via the produced formation water (PFW) discharge. In this study, a new approach was applied to the investigation of the DEG content in PFW discharges and seawater samples from four gas installation platforms in the Adriatic Sea (Italy). The method includes an off-line solid-phase extraction/pre-concentration technique, followed by a nanoscale flow injection/direct-electron ionization (EI) mass spectrometric analysis. Direct-EI is a novel and miniaturized interface for directly coupling a liquid chromatograph with an electron ionization mass spectrometer. The capability to acquire EI spectra, and to operate in selected ion monitoring mode during actual sample analyses, allowed a precise quantification of DEG with a method limit of detection of 31microg/l. In addition, a careful evaluation of the matrix effect showed that, as opposed to electrospray ionization, the response of the Direct-EI interface was not affected by sample interferences.

  2. 78 FR 40128 - Notice of Intent to Prepare a Draft Environmental Impact Statement (EIS) for the Reaches 8, 9...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-03

    ... County Comprehensive Erosion Control (SAJ-2008-04086). The projects overlap (i.e. had proposed the... recreational usage. The Proposed Activities may result in localized shoreline accretion or erosion on the... issued a Notice of Intent for the Central Palm Beach County Comprehensive Erosion Control Project EIS on...

  3. 75 FR 23253 - Notice of Intent To Prepare a Draft Environmental Impact Statement (EIS) for the Central Palm...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-03

    ... (EIS) for the Central Palm Beach County Comprehensive Erosion Control Project in Palm Beach County, FL... recreational uses of the project area, the potential to cause down drift erosion, and other environmental... (R138+400') located in Manalapan. The shoreline in this area has experienced long-term erosion, and...

  4. 78 FR 18325 - Intent To Prepare an Environmental Impact Statement (EIS) for the Formal Training Unit (FTU) and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-26

    ... Unit (FTU) and Main Operating Base 1 (MOB 1) for the Beddown of KC-46A Tanker Aircraft AGENCY... Training Unit (FTU) and Main Operating Base 1 (MOB 1) for the Beddown of KC-46A Tanker Aircraft. The EIS... infrastructure and manpower of the FTU and MOB 1 at existing active duty Air Force installations within the...

  5. 76 FR 53705 - Notice To Rescind a Notice of Intent To Prepare an Environmental Impact Statement (EIS), Ada...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-29

    ... changed and potential impacts from the new concept are not significant and do not warrant an EIS... project was initiated with several concepts derived from previous planning efforts. Then a wide range of... and software improvements would meet project goals without exceeding available revenue....

  6. 77 FR 39322 - Notice to Rescind the Notice of Intent to Prepare an Environmental Impact Statement (EIS...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-02

    ... Greensferry Interchange, combined with removal of the half interchange at Seltice. Impacts to the social... Impact Statement (EIS), Kootenai County, ID AGENCY: Federal Highway Administration. ACTION: Rescind Notice of Intent to prepare an Environmental Impact Statement. SUMMARY: The FHWA is issuing this...

  7. 78 FR 54871 - Notice of Amendment to the Notice of Intent To Prepare an Environmental Impact Statement (EIS...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-06

    ... Environmental Impact Statement (EIS) for the Millennium Bulk Terminals- Longview Shipping Facility Project... Terminals-Longview, LLC (MBTL) is proposing to construct and operate a shipping facility near Longview... associated with the proposed construction and operation of a shipping facility by Millennium Bulk...

  8. 77 FR 58531 - Notice of Intent To Prepare a Joint Environmental Impact Statement (EIS) for the Gateway Pacific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-21

    ... Impact Statement (EIS) for the Gateway Pacific Terminals Bulk Dry Goods Shipping Facility and the Custer... Pacific International Terminal, Inc.'s Gateway Pacific Terminal (GPT) and Burlington Northern Santa Fe..., northwest of Ferndale and south of Birch Bay in an area called Cherry Point. Pacific International...

  9. 78 FR 49484 - Notice of Intent To Prepare a Joint Environmental Impact Statement (EIS) for the Millennium Bulk...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-14

    ... (EIS) for the Millennium Bulk Terminals--Longview Shipping Facility Project AGENCY: U. S. Army Corps of Engineers (Corps), DoD. ACTION: Notice of Intent. SUMMARY: Millennium Bulk Terminals--Longview, LLC (MBTL... and operation of a shipping facility by Millennium Bulk Terminals--Longview (MBTL). Currently,...

  10. Education Is a Human Right. EI Barometer on Human and Trade Union Rights in the Education Sector, 2001.

    ERIC Educational Resources Information Center

    Noonan, Michael A.

    This 2001 edition of Educational International's (EI) "Barometer on Trade Union and Human Rights in the Education Sector" focuses on four fundamental human rights: (1) the right to education; (2) academic freedom; (3) children's right to be protected from exploitation; and (4) workers' rights to form and join trade unions and to organize…

  11. 78 FR 64265 - Notice To Rescind a Notice of Intent To Prepare an Environmental Impact Statement (EIS): State...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-28

    ... Statement (EIS): State Route 71, South Knoxville Boulevard (James White Parkway), From Governor John Sevier..., South Knoxville Boulevard (James White Parkway), from Governor John Sevier Highway (State Route 168) to... the existing Chapman Highway/ Governor John Sevier Highway interchange to Moody Avenue. The proposed...

  12. 76 FR 12755 - Notice of Intent To Prepare an Environmental Impact Statement (EIS) and Hold Public Scoping...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    ... (Reclamation) proposes to prepare an EIS to analyze the potential effects of an update to the M&I WSP. The... consideration of alternatives to the 2001 M&I WSP. The comments coupled with recent significant changes in the... modified, and will include analysis of the adverse and beneficial effects on the quality of the human...

  13. 75 FR 17756 - Availability of the Final General Management Plan and Environmental Impact Statement (GMP/EIS...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-07

    ..., natural, and socioeconomic environments. The Final GMP/EIS contains NPS responses to public comments on... relatively insulated from the surrounding urban conditions. Motorized boating would not be appropriate in... the NPS Planning, Environment, and Public Comment Web site ( http://parkplanning.nps.gov )...

  14. 75 FR 51448 - Withdrawal of Notice for Preparation of an Environmental Impact Statement (EIS) for the Arkansas...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-20

    ... landmass separating the White and Arkansas Rivers, and other required features to ensure navigation on the McClellan-Kerr Arkansas River Navigation System (MKARNS) is maintained. Continued Operation and... Statement (EIS) for the Arkansas White River Cutoff Study AGENCY: Department of the Army, U.S. Army Corps of...

  15. 77 FR 49865 - Notice of Availability of an Environmental Impact Statement (EIS) for the San Francisco Veterans...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-17

    ... AFFAIRS Notice of Availability of an Environmental Impact Statement (EIS) for the San Francisco Veterans... (VA). ACTION: Notice of availability. SUMMARY: Pursuant to the National Environmental Policy Act (NEPA) of 1969, as amended, (42 U.S.C. 4331 et seq.), the Council on Environmental Quality Regulations for...

  16. Early results on energetic particle dynamics and structure from the Energetic Ion Spectrometer (EIS) on the Magnetospheric Multiscale (MMS) mission

    NASA Astrophysics Data System (ADS)

    Cohen, I. J.; Mauk, B.; Westlake, J. H.; Anderson, B. J.; Turner, D. L.; Fennell, J. F.; Spence, H. E.; Baker, D. N.; Pollock, C. J.; Torbert, R. B.; Blake, J. B.; Sibeck, D. G.

    2015-12-01

    The cluster of four, formation-flying spacecraft, comprising the Magnetospheric Multiscale (MMS) mission, launched on 13 March 2015 into near equatorial 1.2 x 12 RE orbits, provides an important new asset for assessing the transport of energy and matter from the distant regions of Earth's magnetosphere into the inner regions. Here we report on early results from the Energetic Ion Spectrometer (EIS) instrument on each of the MMS Spacecraft. EIS provides nearly all-sky energetic ion energy, angle and elemental compositional distributions for < 20 keV for protons and 45 keV for oxygen ions, up to > 1 MeV. It also measures energetic electrons from 25 keV to > 0.5 MeV in support and coordination with the electron-focused Fly's Eye Energetic Particle Spectrometer (FEEPS). During the early phase of the MMS mission, while the full complement of instruments was being commissioned prior to the prime mission phase beginning 1 September 2015, EIS observed dynamic energetic particle injections at the root of the magnetotail between the post-midnight regions and dawn in association with numerous dipolarization fronts and related processes. Here we report on coordinated measurements between MMS's EIS instrument and EIS's sister instrument on the Van Allen Probes, RBSPICE, to further address the relationship between dynamic injections and depolarization fronts in the magnetotail and injections observed deep within the magnetosphere's ring current regions. We also report preliminary result on using energetic particle gradients and anistotropies to diagnose magnetopause structures near mission-identified reconnection sites.

  17. Thermal structure of a hot non-flaring corona from Hinode/EIS

    NASA Astrophysics Data System (ADS)

    Petralia, A.; Reale, F.; Testa, P.; Del Zanna, G.

    2014-04-01

    Aims: In previous studies, a very hot plasma component has been diagnosed in solar active regions through the images in three different narrow-band channels of Atmospheric Imaging Assembly (AIA) on board the Solar Dynamics Observatory (SDO). This diagnostic from extreme ultraviolet (EUV) imaging data has also been supported by the matching morphology of emission in the hot Ca XVII line, as observed with Extreme-Ultraviolet Imaging Spectrometer (EIS) on board Hinode. This evidence is debated because of the unknown distribution of the emission measure along the line of sight. Here we investigate in detail the thermal distribution of one such region using EUV spectroscopic data. Methods: In an active region observed with SDO/AIA, Hinode/EIS, and X-ray telescope (XRT), we select a sub-region with a very hot plasma component and another cooler sub-region for comparison. The average spectrum is extracted for both, and 14 intense lines are selected for analysis that probe the 5.5 < log T < 7 temperature range uniformly. From these lines, the emission measure distributions are reconstructed with the Markov-chain Monte Carlo method. Results are cross-checked in comparison with the two sub-regions, with a different inversion method, with the morphology of the images, and with the addition of fluxes measured with narrow, and broadband imagers. Results: We find that, whereas the cool region has a flat and featureless distribution that drops at temperature log T ≥ 6.3, the distribution of the hot region shows a well-defined peak at log T = 6.6 and gradually decreasing trends on both sides, thus supporting the very hot nature of the hot component diagnosed with imagers. The other cross-checks are consistent with this result. Conclusions: This study provides a completion of the analysis of active region components, and the resulting scenario supports the presence of a minor very hot plasma component in the core, with temperatures log T > 6.6.

  18. Analysis and modelling of recurrent solar flares observed with Hinode/EIS on March 9, 2012

    NASA Astrophysics Data System (ADS)

    Polito, V.; Del Zanna, G.; Valori, G.; Pariat, E.; Mason, H. E.; Dudík, J.; Janvier, M.

    2017-05-01

    Three homologous C-class flares and one last M-class flare were observed by both the Solar Dynamics Observatory (SDO) and the Hinode EUV Imaging Spectrometer (EIS) in the AR 11429 on March 9, 2012. All the recurrent flares occurred within a short interval of time (less than 4 h), showed very similar plasma morphology and were all confined, until the last one when a large-scale eruption occurred. The C-class flares are characterized by the appearance, at approximatively the same locations, of two bright and compact footpoint sources of ≈3-10 MK evaporating plasma, and a semi-circular ribbon. During all the flares, the continuous brightening of a spine-like hot plasma (≈10 MK) structure is also observed. Spectroscopic observations with Hinode/EIS are used to measure and compare the blueshift velocities in the Fe xxiii emission line and the electron number density at the flare footpoints for each flare. Similar velocities, of the order of 150-200 km s-1, are observed during the C2.0 and C4.7 confined flares, in agreement with the values reported by other authors in the study of the last M1.8 class flare. On the other hand, lower electron number densities and temperatures tend to be observed in flares with lower peak soft X-ray flux. In order to investigate the homologous nature of the flares, we performed a non-linear force-free field (NLFFF) extrapolation of the 3D magnetic field configuration in the corona. The NLFFF extrapolation and the Quasi-Separatrix Layers (QSLs) provide the magnetic field context which explains the location of the kernels, spine-like hot plasma and semi-circular brightenings observed in the (non-eruptive) flares. Given the absence of a coronal null point, we argue that the homologous flares were all generated by the continuous recurrence of bald patch reconnection. The movie associated to Fig. 2 is available at http://www.aanda.org

  19. On oscillations found in an active region with EIS on Hinode

    NASA Astrophysics Data System (ADS)

    O'Shea, E.; Doyle, J. G.

    2009-01-01

    Aims: Using temporal series (40'' slot) data in the ion{Fe}{xii} 195 Å line from the extreme-ultraviolet imaging spectrometer (EIS) on board the Hinode satellite, we seek to carry out a statistical study of oscillations in an active region. Methods: Using wavelet techniques, we measure the frequency and duration of oscillations found in the time series data. Stokes I and V data from Hinode's SOT are used to measure photospheric magnetic fields, while an EIS raster is used to provide estimates of LOS velocity and electron density. The measured frequencies are displayed as maps in different bands to aid their analysis. Results: Oscillations over a broad range of frequencies (2-154 mHz) are found throughout the active region at the temperature of ion{Fe}{xii} (log T=6.1 K). Oscillations with frequencies between 2-8 mHz are concentrated in bright plage areas, while oscillations of higher frequency preferentially group at the edges of these areas. Evidence is found for harmonics on the boundary of the active region loop, indicating the presence of standing waves. From a measurement of the lengths and electron density of loops appearing in our active region field-of-view (FOV), together with a knowledge of the periods (frequencies) of the oscillations within the area of these loops, we find a magnetic field value of between 12.2±2.08-18.9±3.40 G, assuming standing fast kink waves. Conclusions: We conclude that waves, which the observed oscillations are signatures of, are common in the active region studied, over a broad range of frequencies. The change in the distribution of the oscillations present at frequencies less than 8 mHz and those at all frequencies above this indicates a variation of the wave mode with frequency, e.g., possibly from slow magnetoacoustic waves in the bright plage regions to fast magnetoacoustic waves at the boundaries of these regions. The preference for higher frequency oscillations to cluster on the edges of regions of high magnetic field

  20. ACCELERATING WAVES IN POLAR CORONAL HOLES AS SEEN BY EIS AND SUMER

    SciTech Connect

    Gupta, G. R.; Banerjee, D.; Teriaca, L.; Solanki, S.; Imada, S.

    2010-07-20

    We present EIS/Hinode and SUMER/SOHO observations of propagating disturbances detected in coronal lines in inter-plume and plume regions of a polar coronal hole. The observation was carried out on 2007 November 13 as part of the JOP196/HOP045 program. The SUMER spectroscopic observation gives information about fluctuations in radiance and on both resolved (Doppler shift) and unresolved (Doppler width) line-of-sight velocities, whereas EIS 40'' wide slot images detect fluctuations only in radiance but maximize the probability of overlapping field of view between the two instruments. From distance-time radiance maps, we detect the presence of propagating waves in a polar inter-plume region with a period of 15-20 minutes and a propagation speed increasing from 130 {+-} 14 km s{sup -1} just above the limb to 330 {+-} 140 km s{sup -1} around 160'' above the limb. These waves can be traced to originate from a bright region of the on-disk part of the coronal hole where the propagation speed is in the range of 25 {+-} 1.3 to 38 {+-} 4.5 km s{sup -1}, with the same periodicity. These on-disk bright regions can be visualized as the base of the coronal funnels. The adjacent plume region also shows the presence of propagating disturbances with the same range of periodicity but with propagation speeds in the range of 135 {+-} 18 to 165 {+-} 43 km s{sup -1} only. A comparison between the distance-time radiance map of the two regions indicates that the waves within the plumes are not observable (may be getting dissipated) far off-limb, whereas this is not the case in the inter-plume region. A correlation analysis was also performed to find out the time delay between the oscillations at several heights in the off-limb region, finding results consistent with those from the analysis of the distance-time maps. To our knowledge, this result provides first spectroscopic evidence of the acceleration of propagating disturbances in the polar region close to the Sun (within 1.2 R/R{sub sun

  1. Genetic and least squares algorithms for estimating spectral EIS parameters of prostatic tissues.

    PubMed

    Halter, Ryan J; Hartov, Alex; Paulsen, Keith D; Schned, Alan; Heaney, John

    2008-06-01

    We employed electrical impedance spectroscopy (EIS) to evaluate the electrical properties of prostatic tissues. We collected freshly excised prostates from 23 men immediately following radical prostatectomy. The prostates were sectioned into 3 mm slices and electrical property measurements of complex resistivity were recorded from each of the slices using an impedance probe over the frequency range of 100 Hz to 100 kHz. The area probed was marked so that following tissue fixation and slide preparation, histological assessment could be correlated directly with the recorded EIS spectra. Prostate cancer (CaP), benign prostatic hyperplasia (BPH), non-hyperplastic glandular tissue and stroma were the primary prostatic tissue types probed. Genetic and least squares parameter estimation algorithms were implemented for fitting a Cole-type resistivity model to the measured data. The four multi-frequency-based spectral parameters defining the recorded spectrum (rho(infinity), Deltarho, f(c) and alpha) were determined using these algorithms and statistically analyzed with respect to the tissue type. Both algorithms fit the measured data well, with the least squares algorithm having a better average goodness of fit (95.2 mOmega m versus 109.8 mOmega m) and a faster execution time (80.9 ms versus 13 637 ms) than the genetic algorithm. The mean parameters, from all tissue samples, estimated using the genetic algorithm ranged from 4.44 to 5.55 Omega m, 2.42 to 7.14 Omega m, 3.26 to 6.07 kHz and 0.565 to 0.654 for rho(infinity), Deltarho, f(c) and alpha, respectively. These same parameters estimated using the least squares algorithm ranged from 4.58 to 5.79 Omega m, 2.18 to 6.98 Omega m, 2.97 to 5.06 kHz and 0.621 to 0.742 for rho(infinity), Deltarho, f(c) and alpha, respectively. The ranges of these parameters were similar to those reported in the literature. Further, significant differences (p < 0.01) were observed between CaP and BPH for the spectral parameters Deltarho and f

  2. VELOCITY MEASUREMENTS FOR A SOLAR ACTIVE REGION FAN LOOP FROM HINODE/EIS OBSERVATIONS

    SciTech Connect

    Young, P. R.; O'Dwyer, B.; Mason, H. E.

    2012-01-01

    The velocity pattern of a fan loop structure within a solar active region over the temperature range 0.15-1.5 MK is derived using data from the EUV Imaging Spectrometer (EIS) on board the Hinode satellite. The loop is aligned toward the observer's line of sight and shows downflows (redshifts) of around 15 km s{sup -1} up to a temperature of 0.8 MK, but for temperatures of 1.0 MK and above the measured velocity shifts are consistent with no net flow. This velocity result applies over a projected spatial distance of 9 Mm and demonstrates that the cooler, redshifted plasma is physically disconnected from the hotter, stationary plasma. A scenario in which the fan loops consist of at least two groups of 'strands'-one cooler and downflowing, the other hotter and stationary-is suggested. The cooler strands may represent a later evolutionary stage of the hotter strands. A density diagnostic of Mg VII was used to show that the electron density at around 0.8 MK falls from 3.2 Multiplication-Sign 10{sup 9} cm{sup -3} at the loop base, to 5.0 Multiplication-Sign 10{sup 8} cm{sup -3} at a projected height of 15 Mm. A filling factor of 0.2 is found at temperatures close to the formation temperature of Mg VII (0.8 MK), confirming that the cooler, downflowing plasma occupies only a fraction of the apparent loop volume. The fan loop is rooted within a so-called outflow region that displays low intensity and blueshifts of up to 25 km s{sup -1} in Fe XII {lambda}195.12 (formed at 1.5 MK), in contrast to the loop's redshifts of 15 km s{sup -1} at 0.8 MK. A new technique for obtaining an absolute wavelength calibration for the EIS instrument is presented and an instrumental effect, possibly related to a distorted point-spread function, that affects velocity measurements is identified.

  3. The Energetic Particle Detector (EPD) Investigation and the Energetic Ion Spectrometer (EIS) for the Magnetospheric Multiscale (MMS) Mission

    NASA Astrophysics Data System (ADS)

    Mauk, B. H.; Blake, J. B.; Baker, D. N.; Clemmons, J. H.; Reeves, G. D.; Spence, H. E.; Jaskulek, S. E.; Schlemm, C. E.; Brown, L. E.; Cooper, S. A.; Craft, J. V.; Fennell, J. F.; Gurnee, R. S.; Hammock, C. M.; Hayes, J. R.; Hill, P. A.; Ho, G. C.; Hutcheson, J. C.; Jacques, A. D.; Kerem, S.; Mitchell, D. G.; Nelson, K. S.; Paschalidis, N. P.; Rossano, E.; Stokes, M. R.; Westlake, J. H.

    2016-03-01

    The Energetic Particle Detector (EPD) Investigation is one of 5 fields-and-particles investigations on the Magnetospheric Multiscale (MMS) mission. MMS comprises 4 spacecraft flying in close formation in highly elliptical, near-Earth-equatorial orbits targeting understanding of the fundamental physics of the important physical process called magnetic reconnection using Earth's magnetosphere as a plasma laboratory. EPD comprises two sensor types, the Energetic Ion Spectrometer (EIS) with one instrument on each of the 4 spacecraft, and the Fly's Eye Energetic Particle Spectrometer (FEEPS) with 2 instruments on each of the 4 spacecraft. EIS measures energetic ion energy, angle and elemental compositional distributions from a required low energy limit of 20 keV for protons and 45 keV for oxygen ions, up to >0.5 MeV (with capabilities to measure up to >1 MeV). FEEPS measures instantaneous all sky images of energetic electrons from 25 keV to >0.5 MeV, and also measures total ion energy distributions from 45 keV to >0.5 MeV to be used in conjunction with EIS to measure all sky ion distributions. In this report we describe the EPD investigation and the details of the EIS sensor. Specifically we describe EPD-level science objectives, the science and measurement requirements, and the challenges that the EPD team had in meeting these requirements. Here we also describe the design and operation of the EIS instruments, their calibrated performances, and the EIS in-flight and ground operations. Blake et al. (The Flys Eye Energetic Particle Spectrometer (FEEPS) contribution to the Energetic Particle Detector (EPD) investigation of the Magnetospheric Magnetoscale (MMS) Mission, this issue) describe the design and operation of the FEEPS instruments, their calibrated performances, and the FEEPS in-flight and ground operations. The MMS spacecraft will launch in early 2015, and over its 2-year mission will provide comprehensive measurements of magnetic reconnection at Earth

  4. 1992 Columbia River Salmon Flow Measures Options Analysis/EIS : Appendices.

    SciTech Connect

    Not Available

    1992-01-01

    This Options Analysis/Environmental Impact Statement (OA/EIS) identifies, presents effects of, and evaluates the potential options for changing instream flow levels in efforts to increase salmon populations in the lower Columbia and Snake rivers. The potential actions would be implemented during 1992 to benefit juvenile and adult salmon during migration through eight run-of-river reservoirs. The Corps of Engineers (Corps) prepared this document in cooperation with the Bonneville Power Administration and the Bureau of Reclamation. The US Fish and Wildlife Service (FWS) is a participating agency. The text and appendices of the document describe the characteristics of 10 Federal projects and one private water development project in the Columbia River drainage basin. Present and potential operation of these projects and their effects on the salmon that spawn and rear in the Columbia and Snake River System are presented. The life history, status, and response of Pacific salmon to current environmental conditions are described. The document concludes with an evaluation of the potential effects that could result from implementing proposed actions. The conclusions are based on evaluation of existing data, utilization of numerical models, and application of logical inference. This volume contains the appendices.

  5. An exploration of the relationship between emotional intelligence (EI) and the Multiple Mini-Interview (MMI).

    PubMed

    Yen, Wendy; Hovey, Richard; Hodwitz, Kathryn; Zhang, Su

    2011-03-01

    The present study explored the relationship between the Multiple Mini-Interview (MMI) admissions process and the Bar-On EQ-i emotional intelligence (EI) instrument in order to investigate the potential for the EQ-i to serve as a proxy measure to the MMI. Participants were 196 health science candidates who completed both the MMI and the EQ-i as part of their admissions procedure at the Michener Institute for Applied Health Sciences. Three types of analyses were conducted to examine the relationship between the two tools: reliability analyses, correlational analyses, and a t-test. The tools were found to be moderately reliable. No significant relationships were found between the MMI and the EQ-i at the total or subscale level. The ability of the EQ-i to discriminate between accepted and not-accepted students was also not supported. These findings do not support the use of the EQ-i as a potential pre-screening tool for the MMI, but rather highlight the need to exercise caution when using emotional intelligence instruments for high-stakes admissions purposes.

  6. Electrochemical Polishing Applications and EIS of a Vitamin B{sub 4}-Based Ionic Liquid

    SciTech Connect

    Wixtrom, Alex I.; Buhler, Jessica E.; Reece, Charles E.; Abdel-Fattah, Tarek M.

    2013-01-01

    Modern particle accelerators require minimal interior surface roughness for Niobium superconducting radio frequency (SRF) cavities. Polishing of the Nb is currently achieved via electrochemical polishing with concentrated mixtures of sulfuric and hydrofluoric acids. This acid-based approach is effective at reducing the surface roughness to acceptable levels for SRF use, but due to acid-related hazards and extra costs (including safe disposal of used polishing solutions), an acid-free method would be preferable. This study focuses on an alternative electrochemical polishing method for Nb, using a novel ionic liquid solution containing choline chloride, also known as Vitamin B{sub 4} (VB{sub 4}). Potentiostatic electrochemical impedance spectroscopy (EIS) was also performed on the VB4-based system. Nb polished using the VB4-based method was found to have a final surface roughness comparable to that achieved via the acid-based method, as assessed by atomic force microscopy (AFM). These findings indicate that acid-free VB{sub 4}-based electrochemical polishing of Nb represents a promising replacement for acid-based methods of SRF cavity preparation.

  7. Molecularly imprinted polymers on graphene oxide surface for EIS sensing of testosterone.

    PubMed

    Liu, Weilu; Ma, Yukai; Sun, Guoxiang; Wang, Shupiao; Deng, Jiayin; Wei, Hong

    2017-06-15

    A novel electrochemical biosensor was developed for ultrasensitive determination of testosterone from femtomolar to micromolar levels via electrochemical impedance spectroscopy (EIS) measurements. The sensor features a nanosized molecularly imprinted polymer (MIP) film that was electrochemically grafted on a graphene-oxide sheets modified electrode. The detection mechanism of this senor is explained via the change of the interfacial impedance that derived from the recognition of the target molecule. Due to the nanosheet structure as well as the high surface area of graphene-oxide, the sensitivity of the MIP sensor is enhanced remarkably. Under an optimized condition, a wide linear range from 1fM to 1µm (1×10(-15)-1×10(-6)molL(-1)) and a detection limit of 0.4fM (4.0×10(-16)molL(-1)) was obtained. This composite film presented a good selectivity over structurally similar steroid hormones, and a long term stability in room temperature for the detection of testosterone. Considering these advantages, the MIP/GO electrochemical biosensor could be a substitute of testosterone immunosensor, and may be further extended to the detection of other endogenous substances.

  8. CON4EI: Evaluation of QSAR models for hazard identification and labelling of eye irritating chemicals.

    PubMed

    Geerts, L; Adriaens, E; Alépée, N; Guest, R; Willoughby, J A; Kandarova, H; Drzewiecka, A; Fochtman, P; Verstraelen, S; Van Rompay, A R

    2017-09-20

    Assessment of ocular irritation is a regulatory requirement in safety evaluation of industrial and consumer products. Although a number of in vitro ocular irritation assays exist, none are capable of fully categorizing chemicals as stand-alone assays. Therefore, the CEFIC-LRI-AIMT6-VITO CON4EI (CONsortium for in vitro Eye Irritation testing strategy) project was developed to assess the reliability of eight in vitro test methods and computational models as well as establishing an optimal tiered-testing strategy. For three computational models (Toxtree, and Case Ultra EYE_DRAIZE and EYE_IRR) performance parameters were calculated. Coverage ranged from 15 to 58%. Coverage was 2 to 3.4 times higher for liquids than for solids. The lowest number of false positives (5%) was reached with EYE_IRR; this model however also gave a high number of false negatives (46%). The lowest number of false negatives (25%) was seen with Toxtree; for liquids Toxtree predicted the lowest number of false negatives (11%), for solids EYE_DRAIZE did ((78%).It can be concluded that the training sets should be enlarged with high quality data. The tested models are not yet sufficiently powerful for stand-alone evaluations, but that they can surely become of value in an integrated weight-of-evidence approach in hazard assessment. Copyright © 2017. Published by Elsevier Ltd.

  9. MagEIS and REPT Observations Related to Low Frequency Waves

    NASA Astrophysics Data System (ADS)

    Fennell, J. F.; Claudepierre, S. G.; Kanekal, S.; Blake, J. B.; Baker, D. N.; Geoffrey, R.; Spence, H. E.

    2015-12-01

    The MagEIS and REPT sensors make comprehensive measurements of energetic particle fluxes and pitch angle distributions during periods of ULF and EMIC wave activity observed by the Van Allen Probes. These waves are thought to play important roles in the radial transport and energization of particles and also important roles in the loss of electrons from the radiation belts. There have been observations of particle responses to ULF waves by electrons like that of Hao et al. 2014 and ULF waves have been correlated with electron precipitation observed by the BARREL mission (Halford et al., 2015). There are observations of resonant interactions between the particles and waves such as those published by Claudepierre et al., 2013 and Dai et al, 2013, plus observations relating EMIC waves to losses of relativistic electrons like that of Usanova et al., 2014 and Zan et al., 2014. Observations like these will be reviewed from the perspective of the particle measurements on the Van Allen Probes. In addition we will give a short summary of measurement improvements planned for the Van Allen Probes extended mission that will better support future particle comparisons with the low frequency waves.

  10. Hinode EIS and XRT Observations of Hot Jets in Coronal Holes - Does the Plasma Escape?

    NASA Astrophysics Data System (ADS)

    Baker, D.; van Driel-Gesztelyi, L.; Kamio, S.; Culhane, J. L.; Harra, L. K.; Sun, J.; Young, P. R.; Matthews, S. A.

    2008-09-01

    X-ray jets have been detected in the extreme ultraviolet (EUV) and soft X-ray observations of Hinode's EIS and XRT instruments. Both instruments were used to observe the jets in polar and on-disk coronal holes (CHs). Here, we present a multi-wavelength study of an X-ray jet and its associated bright point found in an equatorial CH on 19 June 2007. Light curves (LCs) in 22 different emission lines were compared to that of Hinode/XRT. As we found in a previous study of two polar X-ray jets, this jet shows a post-jet increase in its EUV LCs. The post-jet enhancement appears cooler than the jet. We suggest this feature arises because the hot plasma of the jet, having failed to reach escape speeds, cools and falls back along the near vertical paths expected to be created by reconnection with open field lines of CHs. In addition to the increase in post-jet EUV intensity, we found tentative evidence of impact heating possibly caused by the fall-back of plasma.

  11. An electrochemical impedance spectroscopy (EIS) assay measuring the calcification inhibition capacity in biological fluids.

    PubMed

    Ismail, A H; Schäfer, C; Heiss, A; Walter, M; Jahnen-Dechent, W; Leonhardt, S

    2011-08-15

    Pathological calcification of the cardiovascular system is one of the major causes of high mortality and morbidity in dialysis patients. The inhibition of ectopic calcification relies (I) on the formation of calciprotein particles (CPPs), nanospherical complexes of calcium phosphate mineral, fetuin-A and other acidic serum proteins, and (II) on the stabilization of calcium phosphate prenucleation clusters by fetuin-A monomers. In supersaturated serum, mineral ion aggregation leads to a change in the electrical impedance. In this work, we present a method based on electrochemical impedance spectroscopy (EIS) to establish an impedance trace of mineral ion clustering in vitro. In the presence of 20 μM of serum protein fetuin-A, a prototypic calcification inhibitor, we measured a change in impedance (Δ(R)) of 195.52 ± 27.78%Ω compared to 430.41 ± 11.36%Ω in inhibitor-free samples. We also identified a CPP-formation dependency on the actual content of ions and protein in the samples under investigation. Two-step ripening of CPP was also observed. The presented method may form the basis of a simple label-free bedside or online test to be used in routine clinical practice for estimating the calcification risk in serum. Copyright © 2011 Elsevier B.V. All rights reserved.

  12. Investigation into the effect that probe immobilisation method type has on the analytical signal of an EIS DNA biosensor.

    PubMed

    Lillis, Brian; Manning, Mary; Hurley, Eileen; Berney, Helen; Duane, Russell; Mathewson, Alan; Sheehan, Michelle M

    2007-02-15

    The analytical performance of an enhanced surface area electrolyte insulator semiconductor (EIS) device was investigated for DNA sensor development. The work endeavored to advance EIS performance by monitoring the effect of DNA probe layers have on the impedimetric signal during target hybridisation detection. Two universally employed covalent chemistries, direct and spacer-mediated attachment of amino modified probe molecules to amino-functionalised surfaces were investigated. Relative areal densities of immobilised probe were measured on planar and enhanced surface area substrates using epi-fluorescence microscopy. The reproducibility of the each immobilisation method was seen to have a direct effect on the reproducibility of the impedimetric signal. The sensitivity and selectivity was seen to be dependent on the type of immobilisation method. Real time, impedimetric detection of target DNA hybridisation concentrations as low as 25 and 1 nM were possible. The impact that probe concentration had on the impedimetric signal for selective and non-selective interactions was also investigated.

  13. Performance of New Pb-Bi Alloys for Pb-Acid Battery Applications: EIS and Polarization Study

    NASA Astrophysics Data System (ADS)

    Peixoto, Leandro C.; Bortolozo, Ausdinir D.; Garcia, Amauri; Osório, Wislei R.

    2016-06-01

    The present investigation is focused on the evaluation of electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization results, associated with resulting microstructural features of two distinct as-cast Pb-Bi alloys (i.e., 1 and 2.5 wt.% Bi). EIS, potentiodynamic polarization curves, and equivalent circuits are used to analyze the corrosion behavior. The electrochemical parameters show that the corrosion resistance increases when the matrix microstructure is characterized by coarser cells when compared with finer ones. However, when a coarse cellular array is associated with increase in Bi content caused by macrosegregation during casting, the corrosion resistance decreases significantly. Bismuth modifies the anode/cathode area ratio increasing drastically the corrosion action.

  14. Identification and quantification of individual chemical compounds in biogenic secondary organic aerosols using GCxGC-VUV/EI-HRTOFMS

    NASA Astrophysics Data System (ADS)

    Decker, M.; Worton, D. R.; Isaacman, G. A.; Chan, A. W.; Ruehl, C.; Zhao, Y.; Wilson, K. R.; Goldstein, A. H.

    2012-12-01

    Atmospheric aerosols have adverse effects on human health and air quality and affect radiative forcing and thus climate. While the organic fraction of aerosols is substantial, the sources and chemistry leading to the formation of secondary organic aerosols are very poorly understood. Characterizing individual compounds present in organic aerosol provides insights into the sources, formation mechanisms and oxidative transformations that have taken place. Fifteen aerosol samples collected over a 5 day period at the Blodgett Forest Research Station in the Sierra Nevada Mountains, part of the Biosphere Effects on Aerosols and Photochemistry Experiment (BEARPEX) in July 2009, were analyzed using comprehensive two dimensional gas chromatography with high resolution time of flight mass spectrometry (GCxGC-HRTOFMS). Approximately 600 compounds were observed in each sample as significant peaks in the chromatogram. Of these, around a third were identified by matching the unique electron ionization (EI) mass spectrum of each compound to the NIST library of characteristic fragmentation patterns. One filter sample was also analyzed using vacuum ultraviolet ionization (VUV) instead of EI. This 'soft' ionization technique results in much less fragmentation yielding the molecular ion of each compound, from which the exact mass was determined. If the formula of the EI library matched compound equaled the high mass resolution VUV molecular weight within a certain tolerance (< 30 ppm), then the library match was considered confirmed; 226 compounds were identified in this way. Using the VUV technique 234 additional compounds that were not in the EI mass spectral database were assigned chemical formulas based on the observed molecular weights. The chemical formulas in conjunction with the location of the compound in the GCxGC chromatogram were used to provide further classification of these compounds based on their likely functionalization. The broad array of observed oxygenated

  15. Suppression of Eis and expression of Wag31 and GroES in Mycobacterium tuberculosis cytosol under anaerobic culture conditions.

    PubMed

    Maurya, Vineet K; Singh, Kavita; Sinha, Sudhir

    2014-08-01

    A major impediment in chemotherapy of Tuberculosis (TB) is the persistence of M. tuberculosis in a latent or dormant state, possibly perpetuated by paucity of oxygen within the lung granuloma. Proteome analysis of the anaerobically persisting microbe could therefore provide novel targets for drugs against latent TB infection (LTBI). An Indian clinical isolate of M. tuberculosis was cultured under aerobic and anaerobic conditions following Wayne's hypoxia model and its cytosolic proteins were resolved by two-dimensional gel electrophoresis (2DE). Peptide mass fingerprinting of 32 differentially expressed spots using MALDI TOF-TOF MS-MS resulted in identification of 23 proteins. Under the anaerobic culture conditions, expression of 12 of these proteins was highly suppressed (>2 fold reduction in spot volumes), with 4 of them (GrpE, CanB, MoxR1 and Eis) appearing as completely suppressed since corresponding spots were not detectable in the anaerobic sample. On the other hand, 4 proteins were highly expressed, with two of them (Wag31 and GroES) being uniquely expressed under anaerobic conditions. Suppression of Eis could make the anaerobically persisting bacilli susceptible to the aminoglycoside antibiotics which are known to be acetylated and inactivated by Eis. Although all 4 overexpressed proteins can be considered as putative drug targets for LTBI, Wag31 appears particularly interesting in view of its role in the cell wall biogenesis.

  16. Simultaneous determination of some artificial sweeteners in ternary formulations by FT-IR and EI-MS

    NASA Astrophysics Data System (ADS)

    Tosa, Nicoleta; Moldovan, Zaharie; Bratu, Ioan

    2012-02-01

    Artificial sweeteners are widely used in food, beverage and pharmaceutical industries all over the world. In this study some non-nutritive sweeteners such as aspartame, acesulfame-K, sodium cyclamate and sodium saccharin were simultaneously determined in ternary mixtures using FT-IR and EI-MS measurements. FT-IR method is based on direct measurements of the peak height values and area centered on 1736 cm-1, 836 cm-1, 2854 cm-1 and 1050 cm-1 for aspartame, acesulfame-K, sodium cyclamate and sodium saccharin, respectively. Mass spectrometry determinations show the characteristic peaks at m/z 91 and 262 for aspartame,m/z 43 and 163 acesulfame-K,m/z 83 and 97 for sodium cyclamate andm/z 104 and 183 for sodium saccharin. The results obtained by EI-MS in different formulations are in agreement with the FT-IR ones and provide also essential data concerning the purity grade of the components. It is concluded that FT-IR and EI-MS procedures developed in this work represent a fast, sensitive and low cost alternative in the quality control of such sweeteners in different ternary formulations.

  17. Nanostructured gold microelectrodes for SERS and EIS measurements by incorporating ZnO nanorod growth with electroplating

    PubMed Central

    Zong, Xianli; Zhu, Rong; Guo, Xiaoliang

    2015-01-01

    In this paper, a fine gold nanostructure synthesized on selective planar microelectrodes in micro-chip is realized by using an advanced hybrid fabrication approach incorporating growth of nanorods (NRs) with gold electroplating. By this developed nanostructure, integration of in-situ surface-enhanced Raman spectroscopy (SERS) detection with electrochemical impedance spectroscopy (EIS) measurement for label-free, nondestructive, real-time and rapid monitoring on a single cell has been achieved. Moreover, parameters of Au nanostructures such as size of nanoholes/nanogaps can be controllably adjusted in the fabrication. We have demonstrated a SERS enhancement factor of up to ~2.24 × 106 and double-layer impedance decrease ratio of 90% ~ 95% at low frequency range below 200 kHz by using nanostructured microelectrodes. SERS detection and in-situ EIS measurement of a trapped single cell by using planar microelectrodes are realized to demonstrate the compatibility, multi-functions, high-sensitivity and simplicity of the micro-chip system. This dual function platform integrating SERS and EIS is of great significance in biological, biochemical and biomedical applications. PMID:26558325

  18. Supplement Analysis for the Transmission System Vegetation Management Program FEIS (DOE/EIS-0285/SA-142- KeelerOregon City #2)

    SciTech Connect

    Barndt, Shawn L.

    2003-04-04

    Supplement Analysis for the Transmission System Vegetation Management Program FEIS (DOE/EIS-0285/SA-142- KeelerOregon #2). Bonneville Power Administration proposes to remove vegetation alongside Transmission Right-of-Ways

  19. Coronal hole boundaries evolution at small scales. III. EIS and SUMER views

    NASA Astrophysics Data System (ADS)

    Madjarska, M. S.; Huang, Z.; Doyle, J. G.; Subramanian, S.

    2012-09-01

    Context. We report on the plasma properties of small-scale transient events identified in the quiet Sun, coronal holes and their boundaries. Aims: We aim at deriving the physical characteristics of events that were identified as small-scale transient brightenings in XRT images. Methods: We used spectroscopic co-observations from SUMER/SoHO and EIS/Hinode combined with high-cadence imaging data from XRT/Hinode. We measured Doppler shifts using single and multiple Gaussian fits of the transition region and coronal lines as well as electron densities and temperatures. We combined co-temporal imaging and spectroscopy to separate brightening expansions from plasma flows. Results: The transient brightening events in coronal holes and their boundaries were found to be very dynamical, producing high-density outflows at high speeds. Most of these events represent X-ray jets from pre-existing or newly emerging coronal bright points at X-ray temperatures. The average electron density of the jets is log10 Ne ≈ 8.76 cm-3 while in the flaring site it is log10 Ne ≈ 9.51 cm-3. The jet temperatures reach a maximum of 2.5 MK but in the majority of the cases the temperatures do not exceed 1.6 MK. The footpoints of jets have maximum temperatures of 2.5 MK, though in a single event scanned a minute after the flaring the measured temperature was 12 MK. The jets are produced by multiple microflaring in the transition region and corona. Chromospheric emission was only detected in their footpoints and was only associated with downflows. The Doppler shift measurements in the quiet Sun transient brightenings confirmed that these events do not produce jet-like phenomena. The plasma flows in these phenomena remain trapped in closed loops. Conclusions: We can conclude that the dynamic day-by-day and even hour-by-hour small-scale evolution of coronal hole boundaries reported in Paper I is indeed related to coronal bright points. The XRT observations reported in Paper II revealed that these

  20. Emergence of low noise frustrated states in E/I balanced neural networks.

    PubMed

    Recio, I; Torres, J J

    2016-12-01

    We study emerging phenomena in binary neural networks where, with a probability c synaptic intensities are chosen according with a Hebbian prescription, and with probability (1-c) there is an extra random contribution to synaptic weights. This new term, randomly taken from a Gaussian bimodal distribution, balances the synaptic population in the network so that one has 80%-20% relation in E/I population ratio, mimicking the balance observed in mammals cortex. For some regions of the relevant parameters, our system depicts standard memory (at low temperature) and non-memory attractors (at high temperature). However, as c decreases and the level of the underlying noise also decreases below a certain temperature Tt, a kind of memory-frustrated state, which resembles spin-glass behavior, sharply emerges. Contrary to what occurs in Hopfield-like neural networks, the frustrated state appears here even in the limit of the loading parameter α→0. Moreover, we observed that the frustrated state in fact corresponds to two states of non-vanishing activity uncorrelated with stored memories, associated, respectively, to a high activity or Up state and to a low activity or Down state. Using a linear stability analysis, we found regions in the space of relevant parameters for locally stable steady states and demonstrated that frustrated states coexist with memory attractors below Tt. Then, multistability between memory and frustrated states is present for relatively small c, and metastability of memory attractors can emerge as c decreases even more. We studied our system using standard mean-field techniques and with Monte Carlo simulations, obtaining a perfect agreement between theory and simulations. Our study can be useful to explain the role of synapse heterogeneity on the emergence of stable Up and Down states not associated to memory attractors, and to explore the conditions to induce transitions among them, as in sleep-wake transitions.

  1. Quasi-periodic Fluctuations and Chromospheric Evaporation in a Solar Flare Ribbon Observed by Hinode/EIS, IRIS, and RHESSI

    NASA Astrophysics Data System (ADS)

    Brosius, Jeffrey W.; Daw, Adrian N.; Inglis, Andrew R.

    2016-10-01

    The Hinode/Extreme-ultraviolet Imaging Spectrometer (EIS) obtained rapid cadence (11.2 s) EUV stare spectra of an M7.3 flare ribbon in AR 12036 on 2014 April 18. Quasi-periodic (P ≈ 75.6 ± 9.2 s) intensity fluctuations occurred in emission lines of O iv, Mg vi, Mg vii, Si vii, Fe xiv, and Fe xvi during the flare's impulsive rise, and ended when the maximum intensity in Fe xxiii was reached. The profiles of the O iv-Fe xvi lines reveal that they were all redshifted during most of the interval of quasi-periodic intensity fluctuations, while the Fe xxiii profile revealed multiple components including one or two highly blueshifted ones. This indicates that the flare underwent explosive chromospheric evaporation during its impulsive rise. Fluctuations in the relative Doppler velocities were seen, but their amplitudes were too subtle to extract significant quasi-periodicities. RHESSI detected 25-100 keV hard-X-ray sources in the ribbon near the EIS slit's pointing position during the peaks in the EIS intensity fluctuations. The observations are consistent with a series of energy injections into the chromosphere by nonthermal particle beams. Electron densities derived with Fe xiv (4.6 × 1010 cm-3) and Mg vii (7.8 × 109 cm-3) average line intensity ratios during the interval of quasi-periodic intensity fluctuations, combined with the radiative loss function of an optically thin plasma, yield radiative cooling times of 32 s at 2.0 × 106 K, and 46 s at 6.3 × 105 K (about half the quasi-period); assuming Fe xiv's density for Fe xxiii yields a radiative cooling time of 103 s (13 times the quasi-period) at 1.4 × 107 K.

  2. Evaluation of inorganic zinc-rich primers using Electrochemical Impedance Spectroscopy (EIS) in combination with atmospheric exposure

    NASA Technical Reports Server (NTRS)

    Calle, Luz M.

    1994-01-01

    This investigation explored the use of Electrochemical Impedance Spectroscopy (EIS) in combination with atmospheric exposure as a short term method for analyzing the performance of twenty-one commercially available zinc-rich primers. The twenty-one zinc-rich primers were: Carboline CZ-11, Ameron Devoe-Marine Catha-Coat 304, Briner V-65, Ameron D-21-9, Sherwin Williams Zinc Clad II, Carboline CZ-D7, Ameron D-4, Dupont Ganicin 347WB, Porter TQ-4374H, Inorganic Coatings IC-531, Subox Galvanox IV, Southern Coatings Chemtec 600, GLidden Glidzinc 5530, Byco SP-101, Tnemec 90E-75, Devoe Catha-Coat 302H, Glidden Glidzinc 5536, Koppers 701, Ameron D-21-5, Coronado 935-152, and Subox Galvanox V. Data were also collected on galvanized steel for comparison purposes. A library of Bode magnitude plots was generated for each coating including curves for the initial time and after each week of atmospheric exposure at the Beach Corrosion Test site near the Space Shuttle launch pad at the Kennedy Space Center for up to four weeks. Subsequent measurements were collected after 8 weeks and after one year of atmospheric exposure. Analysis of the impedance data was performed with the purpose of identifying parameters that could be used to predict the long-term performance of zinc-rich primers. It has been shown that there is a correlation between the long-term performance of zinc-rich primers and several parameters obtained from EIS measurements in combination with atmospheric exposure. The equivalent circuit R2(R2C(R3W)) provided a satisfactory fit for the EIS data. The corrosion potential and the R2 resistance are parameters indicative of the galvanic mechanism of protection. The capacitance of the coating is related to the barrier mechanism of protection.

  3. Quasi-Periodic Fluctuations and Chromospheric Evaporation in a Solar Flare Ribbon Observed by Hinode/EIS, IRIS, and RHESSI

    NASA Technical Reports Server (NTRS)

    Brosius, Jeffrey W.; Daw, Adrian N.; Inglis, Andrew R.

    2016-01-01

    The Hinode/Extreme-ultraviolet Imaging Spectrometer (EIS) obtained rapid cadence (11.2 s) EUV stare spectra of an M7.3 flare ribbon in AR 12036 on 2014 April 18. Quasi-periodic (P approx. = 75.6 +/- 9.2 s) intensity fluctuations occurred in emission lines of O IV, Mg VI, Mg VII, Si VII, Fe XIV, and Fe XVI during the flare's impulsive rise, and ended when the maximum intensity in Fe XXIII was reached. The profiles of the O IV- Fe XVI lines reveal that they were all redshifted during most of the interval of quasi-periodic intensity fluctuations, while the Fe XXIII profile revealed multiple components including one or two highly blueshifted ones. This indicates that the flare underwent explosive chromospheric evaporation during its impulsive rise. Fluctuations in the relative Doppler velocities were seen, but their amplitudes were too subtle to extract significant quasi-periodicities. RHESSI detected 25-100 keV hard-X-ray sources in the ribbon near the EIS slit's pointing position during the peaks in the EIS intensity fluctuations. The observations are consistent with a series of energy injections into the chromosphere by nonthermal particle beams. Electron densities derived with Fe XIV (4.6 x 10(exp 10) per cu cm) and Mg VII (7.8 x 10(exp 9) per cu cm) average line intensity ratios during the interval of quasi-periodic intensity fluctuations, combined with the radiative loss function of an optically thin plasma, yield radiative cooling times of 32 s at 2.0 x 10(exp 6) K, and 46 s at 6.3 x 10(exp 5) K (about half the quasi-period); assuming Fe XIV's density for Fe XXIII yields a radiative cooling time of 10(exp 3) s (13 times the quasi-period) at 1.4 x 10(exp 7) K.

  4. Short-term plasticity regulates the E/I ratio and the temporal window for spike integration in CA1 pyramidal cells

    PubMed Central

    Bartley, Aundrea F.; Dobrunz, Lynn E.

    2016-01-01

    Many neurodevelopmental and neuropsychiatric disorders have an imbalance between excitation (E) and inhibition (I) caused by synaptic alterations. The proper E/I balance is especially critical in CA1 pyramidal cells because they control hippocampal output. Activation of Schaffer collateral axons causes direct excitation of CA1 pyramidal cells, quickly followed by disynaptic feed-forward inhibition, stemming from synaptically induced firing of GABAergic interneurons. Both excitatory and inhibitory synapses are modulated by short-term plasticity, potentially causing dynamic tuning of the E/I ratio. However, the effects of short-term plasticity on the E/I ratio in CA1 pyramidal cells are not yet known. To determine this we recorded disynaptic IPSCs and E/I ratio in CA1 pyramidal cells in acute hippocampal slices from juvenile mice. We find that while inhibitory synapses have paired-pulse depression, disynaptic inhibition instead expresses paired-pulse facilitation (≤ 200 ms intervals), caused by increased recruitment of feed-forward interneurons. Although enhanced disynaptic inhibition helps constrain paired-pulse facilitation of excitation, the E/I ratio is still larger on the second pulse, increasing pyramidal cell spiking. Surprisingly, this occurs without compromising the precision of spike timing. The E/I balance regulates the temporal spike integration window from multiple inputs; here we show that paired-pulse stimulation can broaden the spike integration window. Together, we find that the combined effects of short-term plasticity of disynaptic inhibition and monosynaptic excitation alter the E/I balance onto CA1 pyramidal cells, leading to dynamic modulation of spike probability and spike integration window. Short-term plasticity is therefore an important mechanism for modulating signal processing of hippocampal output. PMID:25903384

  5. NREL Develops OpenEI.org, a Public Website Where Energy Data can be Generated, Shared, and Compared (Fact Sheet)

    SciTech Connect

    Not Available

    2013-12-01

    The National Renewable Energy Laboratory (NREL) has developed OpenEI.org, a public, open, data-sharing platform where consumers, analysts, industry experts, and energy decision makers can go to boost their energy IQs, search for energy data, share data, and get access to energy applications. The free site blends elements of social media, linked open-data practices, and MediaWiki-based technology to build a collaborative environment for creating and sharing energy data with the world. The result is a powerful platform that is helping government and industry leaders around the world define policy options, make informed investment decisions, and create new businesses.

  6. Structural aspect of the manifestation of thermal brittleness in a maraging steel of the EI-832 type

    NASA Astrophysics Data System (ADS)

    Schastlivtsev, V. M.; Yakovleva, I. L.; Tereshchenko, N. A.; Kruglov, A. A.

    2010-02-01

    The character of fracture, phase composition, and structure of a maraging steel of the EI-832 type in large forged pieces (90 mm and more in cross section) have been investigated. Structural factors responsible for the level of impact toughness of the steel subjected to aging in a forged state and after quenching have been revealed. It has been shown that for this steel the manifestation of thermal brittleness that is caused by precipitation of dispersed titanium carbonitrides at grain boundaries and is not eliminated upon subsequent conventional heat treatment is possible.

  7. Integration of GC/EI-MS and GC/NCI-MS for simultaneous quantitative determination of opiates, amphetamines, MDMA, ketamine, and metabolites in human hair.

    PubMed

    Wu, Ya-Hsueh; Lin, Keh-Liang; Chen, Su-Chin; Chang, Yan-Zin

    2008-07-15

    In this paper, the possibility of using a multiple ionization mode approach of GC/MS was developed for the simultaneous hair testing of common drugs of abuse in Asia, including amphetamines (amphetamine, AP; methamphetamine, MA; methylenedioxy amphetamine, MDA; methylenedioxy methamphetamine, MDMA; methylenedioxy ethylamphetamine, MDEA), ketamine (ketamine, K; norketamine, NK), and opiates (morphine, MOR; codeine, COD; 6-acetylmorphine, 6-AM). This strategy integrated the characteristics of gas chromatography-mass spectrometry (GC-MS) using electron impact ionization (EI) and negative chemical ionization (NCI). Hair samples (25 mg) were washed, cut, and incubated overnight at 25 degrees C in methanol-trifluoroacetic acid (methanol-TFA). The samples were extracted by solid phase extraction (SPE) procedure, derivatized using heptafluorobutyric acid anhydride (HFBA) at 70 degrees C for 30 min, and the derivatives analyzed by GC-MS with EI and NCI. The limit of detection (LOD) with GC/EI-MS analysis obtained were 0.03 ng/mg for AP, MA, MDA, MDMA, and MDEA; 0.05 ng/mg for K, NK, MOR, and COD; and 0.08 ng/mg for 6-AM. The LOD of GC/NCI-MS analysis was much lower than GC/EI-MS analysis. The LOD obtained were 30 pg/mg for AP and MDA in GC/EI-MS and 2 pg/mg in GC/NCI-MS. Therefore, the sensitivity of AP and MDA in GC/NCI-MS was improved from 15-fold compared with EI. The sensitivity of AP, MA, MDA, MDMA, MDEA, MOR, and COD was improved from 15- to 60-fold compared with EI. In addition, the sensitivity of 6-AM increased 8-fold through selection of m/z 197 for the quantitative ion. Moreover, K and NK could dramatically improve their sensitivity at 200- and 2000-fold. The integration of GC/EI-MS and GC/NCI-MS can obtain the high sensitivity and complementary results of drugs of abuse in hair. Six hair samples from known drug abusers were examined by this new strategy. These results show that integrating the characteristics of GC/EI-MS and GC/NCI-MS were not only enhancement of

  8. Supplement Analysis for the Watershed Management Program EIS--Tapteal Bend Riparian Corridor Restoration Project

    SciTech Connect

    N /A

    2004-08-11

    The Bonneville Power Administration is proposing to fund the restoration of approximately 500 feet of streambank along the Yakima River at river mile 8, upstream of the Van Giesen Bridge on SR 224, in and between Richland and West Richland, Washington. This project will also result in the acquisition of Fox Island, a 12-acre island directly across the river from the restoration area. There is no development planned for the island. The proposed project includes: The installation of a bio-engineered streambank that incorporates barbs to capture silt and deflect flow, roughened rock or log toes, a riparian buffer, soil reinforcement, and bank grading. Long-term photo-point and plot sampling will also be implemented to evaluate the effectiveness and success of the restoration project. The NEPA compliance checklist for this project was completed by Darrel Sunday, a contractor with Sunday and Associates, Inc. (April 4, 2004), and meets the standards and guidelines for the Watershed Management Program Environmental Impact Statement (EIS) and Record of Decision (ROD). The Endangered Species Act (ESA) listed species that may occur in the general vicinity of the project area are the pygmy rabbit, bald eagle, bull trout, Ute ladies'-tresses, and mid-Columbia Steelhead. The pygmy rabbit, bald eagle, and Ute ladies'Tresses are not known to occur in the immediate project vicinity, and it was determined that the proposed restoration project would have no effect on these species. It is difficult to determine if bull trout occur within the Tapteal project area and Dave Carl of the Washington Department of Fish & Wildlife was contacted and concurred with this assumption. It was determined that the project may affect, but is not likely to adversely affect bull trout, and the U.S. Fish & Wildlife Service has concurred with that determination (July 28, 2004). For the mid-Columbia Steelhead, an anadromous fish species, BPA has determined that if conducted in accordance with the

  9. Supplement Analysis for the Watershed Management Program EIS --Idaho Model Watershed Habitat Projects - Pahsimeroi Fence Crossing

    SciTech Connect

    N /A

    2004-08-11

    The Bonneville Power Administration is proposing to fund the installation of a fenced stream crossing over the Pahsimeroi River to enhance a livestock riparian enclosure. This structure would include up to four wood fence posts and two deadman anchors buried in the ground. The goal of this project is to enhance salmon and steelhead rearing and migration habitat by preventing livestock from entering the riparian area via the river. The NEPA compliance checklist for this project was completed by Carl Rudeen with the Custer Soil and Water Conservation District (August 4, 2004) and meets the standards and guidelines for the Watershed Management Program Environmental Impact Statement (EIS) and Record of Decision (ROD). The Endangered Species Act (ESA) listed species that may occur in the general vicinity of the project area are gray wolf, Canada lynx, bald eagle, Ute ladies'Tresses, Snake River chinook salmon, Snake River steelhead trout, and Columbia River Basin bull trout. It was determined that the proposed fence crossing construction project would have no effect on these species. Bald eagle, gray wolf and Canada lynx are not known to occur in the immediate project vicinity. Since the site is used primarily as livestock pasture it does not lend itself to the presence of Ute ladies'Tresses. ESA listed fish may be present in the project vicinity but will not be affected because the project does not involve instream work. Soil disturbance will be limited to the livestock pasture and to two holes that will be used to bury anchors for the suspended portion of the fence. Required river crossings will be made on foot. Requirements associated with Section 106 of the National Historic Preservation Act were handled by the Natural Resource Conservation Service (NRCS), in cooperation with staff from the U.S. Forest Service (Boise National Forest), under their existing Programmatic Agreement with the Idaho State Historic Preservation Office (SHPO). A description of the Pahsimeroi

  10. A rapid method for the identification of nitrocellulose in high explosives and smokeless powders using GC-EI-MS.

    PubMed

    Chajistamatiou, Aikaterini S; Bakeas, Evangelos B

    2016-05-01

    Nitrocellulose (NC) is one of the most common ingredients in explosive mixtures, however because of its non-volatility, its detection using Gas Chromatography-Electron Ionization-Mass Spectrometry (GC-EI-MS) has not been achieved until today. A rapid method for the identification of NC in bulk explosives using GC-EI-MS was developed. The sample preparation is simple and takes place in a test tube, employing standard equipment of a forensics laboratory. The protocol was optimized and applied to seven, both high and low, commercial explosives, which contained the substance of interest. Moreover, three explosives in the absence of NC were tested to cross check for false positives. Fourteen different standard explosive substances that are usually found in explosive mixtures were then employed in order to monitor the effect of the method on these compounds and check for interferences. Results showed that NC was detected, by its trimethylsilyl (TMS) derivatives, in all the explosive mixtures analyzed and no false positives were observed. The proposed method showed selectivity for NC, as it had no interference coming from other ingredients of explosive mixtures. The protocol introduced offers considerable improvement in identifying the individual components of an explosive mixture and contributes in successful classification of explosives. Copyright © 2016 Elsevier B.V. All rights reserved.

  11. Reelin-Haploinsufficiency Disrupts the Developmental Trajectory of the E/I Balance in the Prefrontal Cortex.

    PubMed

    Bouamrane, Lamine; Scheyer, Andrew F; Lassalle, Olivier; Iafrati, Jillian; Thomazeau, Aurore; Chavis, Pascale

    2016-01-01

    The reelin gene is a strong candidate in the etiology of several psychiatric disorders such as schizophrenia, major depression, bipolar disorders, and autism spectrum disorders. Most of these diseases are accompanied by cognitive and executive-function deficits associated with prefrontal dysfunctions. Mammalian prefrontal cortex (PFC) development is characterized by a protracted postnatal maturation constituting a period of enhanced vulnerability to psychiatric insults. The identification of the molecular components underlying this prolonged postnatal development is necessary to understand the synaptic properties of defective circuits participating in these psychiatric disorders. We have recently shown that reelin plays a key role in the maturation of glutamatergic functions in the postnatal PFC, but no data are available regarding the GABAergic circuits. Here, we undertook a cross-sectional analysis of GABAergic function in deep layer pyramidal neurons of the medial PFC of wild-type and haploinsufficient heterozygous reeler mice. Using electrophysiological approaches, we showed that decreased reelin levels impair the maturation of GABAergic synaptic transmission without affecting the inhibitory nature of GABA. This phenotype consequently impacted the developmental sequence of the synaptic excitation/inhibition (E/I) balance. These data indicate that reelin is necessary for the correct maturation and refinement of GABAergic synaptic circuits in the postnatal PFC and therefore provide a mechanism for altered E/I balance of prefrontal circuits associated with psychiatric disorders.

  12. CON4EI: Selection of the reference chemicals for hazard identification and labelling of eye irritating chemicals.

    PubMed

    Adriaens, E; Alépée, N; Kandarova, H; Drzewieckac, A; Gruszka, K; Guest, R; Willoughby, J A; Verstraelen, S; Van Rompay, A R

    2017-10-01

    Assessment of the acute eye irritation potential is part of the international regulatory requirements for testing of chemicals. In the past, several prospective and retrospective validation studies have taken place in the area of serious eye damage/eye irritation testing. Success in terms of complete replacement of the regulatory in vivo Draize rabbit eye test has not yet been achieved. A very important aspect to ensure development of successful alternative test methods and/or strategies for serious eye damage/eye irritation testing is the selection of appropriate reference chemicals. A set of 80 reference chemicals was selected for the CEFIC-LRI-AIMT6-VITO CON4EI (CONsortium for in vitro Eye Irritation testing strategy) project, in collaboration with Cosmetics Europe, from the Draize Reference Database published by Cosmetics Europe based on key criteria that were set in their paper (e.g. balanced by important driver of classification and physical state). The most important goals of the CON4EI project were to identify the performance of eight in vitro alternative tests in terms of driver of classification and to identify similarities/differences between the methods in order the build a successful testing strategy that can discriminate between all UN GHS categories. This paper provides background on selection of the test chemicals. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Reelin-Haploinsufficiency Disrupts the Developmental Trajectory of the E/I Balance in the Prefrontal Cortex

    PubMed Central

    Bouamrane, Lamine; Scheyer, Andrew F.; Lassalle, Olivier; Iafrati, Jillian; Thomazeau, Aurore; Chavis, Pascale

    2017-01-01

    The reelin gene is a strong candidate in the etiology of several psychiatric disorders such as schizophrenia, major depression, bipolar disorders, and autism spectrum disorders. Most of these diseases are accompanied by cognitive and executive-function deficits associated with prefrontal dysfunctions. Mammalian prefrontal cortex (PFC) development is characterized by a protracted postnatal maturation constituting a period of enhanced vulnerability to psychiatric insults. The identification of the molecular components underlying this prolonged postnatal development is necessary to understand the synaptic properties of defective circuits participating in these psychiatric disorders. We have recently shown that reelin plays a key role in the maturation of glutamatergic functions in the postnatal PFC, but no data are available regarding the GABAergic circuits. Here, we undertook a cross-sectional analysis of GABAergic function in deep layer pyramidal neurons of the medial PFC of wild-type and haploinsufficient heterozygous reeler mice. Using electrophysiological approaches, we showed that decreased reelin levels impair the maturation of GABAergic synaptic transmission without affecting the inhibitory nature of GABA. This phenotype consequently impacted the developmental sequence of the synaptic excitation/inhibition (E/I) balance. These data indicate that reelin is necessary for the correct maturation and refinement of GABAergic synaptic circuits in the postnatal PFC and therefore provide a mechanism for altered E/I balance of prefrontal circuits associated with psychiatric disorders. PMID:28127276

  14. The use of electrochemical impedance spectroscopy (EIS) in the evaluation of the electrochemical properties of a microbial fuel cell.

    PubMed

    Manohar, Aswin K; Bretschger, Orianna; Nealson, Kenneth H; Mansfeld, Florian

    2008-04-01

    Electrochemical impedance spectroscopy (EIS) has been used to determine several electrochemical properties of the anode and cathode of a mediator-less microbial fuel cell (MFC) under different operational conditions. These operational conditions included a system with and without the bacterial catalyst and EIS measurements at the open-circuit potential of the anode and the cathode or at an applied cell voltage. In all cases the impedance spectra followed a simple one-time-constant model (OTCM) in which the solution resistance is in series with a parallel combination of the polarization resistance and the electrode capacitance. Analysis of the impedance spectra showed that addition of Shewanella oneidensis MR-1 to a solution of buffer and lactate greatly increased the rate of the lactate oxidation at the anode under open-circuit conditions. The large decrease of open-circuit potential of the anode increased the cell voltage of the MFC and its power output. Measurements of impedance spectra for the MFC at different cell voltages resulted in determining the internal resistance (R(int)) of the MFC and it was found that R(int) is a function of cell voltage. Additionally, R(int) was equal to R(ext) at the cell voltage corresponding to maximum power, where R(ext) is the external resistance that must be applied across the circuit to obtain the maximum power output.

  15. SmartGrid: Quarterly Data Summaries from the Data Hub and SmartGrid Project Information (from OpenEI and SmartGrid.gov)

    DOE Data Explorer

    Both OpenEI and SmartGrid.gov are DOE portals to a wealth of information about the federal initiatives that support the development of the technologies, policies and projects transforming the electric power industry. Projects funded through the U.S. Recovery Act are organized by type and pinned to an interactive map at http://en.openei.org/wiki/Gateway:Smart_Grid. Each project title links to more detailed information. The Quarterly Data Summaries from the Data Hub at SmartGrid.gov are also available on OpenEI at http://en.openei.org/datasets/node/928. In addition, the SmartGrid Information Center contains documents and reports that can be searched or browsed. Smart Grid Resources introduces international SmartGrid programs and sites, while OpenEI encourages users to add SmartGrid information to the repository.

  16. LPS resistance of SPRET/Ei mice is mediated by Gilz, encoded by the Tsc22d3 gene on the X chromosome

    PubMed Central

    Pinheiro, Iris; Dejager, Lien; Petta, Ioanna; Vandevyver, Sofie; Puimège, Leen; Mahieu, Tina; Ballegeer, Marlies; Van Hauwermeiren, Filip; Riccardi, Carlo; Vuylsteke, Marnik; Libert, Claude

    2013-01-01

    Natural variation for LPS-induced lethal inflammation in mice is useful for identifying new genes that regulate sepsis, which could form the basis for novel therapies for systemic inflammation in humans. Here we report that LPS resistance of the inbred mouse strain SPRET/Ei, previously reported to depend on the glucocorticoid receptor (GR), maps to the distal region of the X-chromosome. The GR-inducible gene Tsc22d3, encoding the protein Gilz and located in the critical region on the X-chromosome, showed a higher expressed SPRET/Ei allele, regulated in cis. Higher Gilz levels were causally related to reduced inflammation, as shown with knockdown and overexpression studies in macrophages. Transient overexpression of Gilz by hydrodynamic plasmid injection confirmed that Gilz protects mice against endotoxemia Our data strongly suggest that Gilz is responsible for the LPS resistance of SPRET/Ei mice and that it could become a treatment option for sepsis. PMID:23495141

  17. APCI as an innovative ionization mode compared with EI and CI for the analysis of a large range of organophosphate esters using GC-MS/MS.

    PubMed

    Halloum, Wafaa; Cariou, Ronan; Dervilly-Pinel, Gaud; Jaber, Farouk; Le Bizec, Bruno

    2017-01-01

    Organophosphate esters (OPEs) are chemical compounds incorporated into materials as flame-proof and/or plasticizing agents. In this work, 13 non-halogenated and 5 halogenated OPEs were studied. Their mass spectra were interpreted and compared in terms of fragmentation patterns and dominant ions via various ionization techniques [electron ionization (EI) and chemical ionization (CI) under vacuum and corona discharge atmospheric pressure chemical ionization (APCI)] on gas chromatography coupled to mass spectrometry (GC-MS). The novelty of this paper relies on the investigation of APCI technique for the analysis of OPEs via favored protonation mechanism, where the mass spectra were mostly dominated by the quasi-molecular ion [M + H](+) . The EI mass spectra were dominated by ions such as [H4 PO4 ](+) , [M-R](+) , [M-Cl](+) , and [M-Br](+) , and for some non-halogenated aryl OPEs, [M](+●) was also observed. The CI mass spectra in positive mode were dominated by [M + H](+) and sometimes by [M-R](+) , while in negative mode, [M-R](-) and more particularly [X](-) and [X2 ](-●) were mainly observed for the halogenated OPEs. Both EI and APCI techniques showed promising results for further development of instrumental method operating in selective reaction monitoring mode. Instrumental detection limits by using APCI mode were 2.5 to 25 times lower than using EI mode for the non-brominated OPEs, while they were determined at 50-100 times lower by the APCI mode than by the EI mode, for the two brominated OPEs. The method was applied to fish samples, and monitored transitions by using APCI mode showed higher specificity but lower stability compared with EI mode. The sensitivity in terms of signal-to-noise ratio varying from one compound to another. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  18. Influence of hydrogen on the strength and ductility of 30KhGSA and EI659 steels in quasi-static and shock-loading tests

    NASA Astrophysics Data System (ADS)

    Ogorodnikov, V. A.; Yukhimchuk, A. A.; Mochalov, M. A.; Andramanov, A. V.; Baurin, A. Yu.; Blikov, A. O.; Boitsov, I. E.; Erunov, S. V.; Maksimkin, I. P.; Malkov, I. L.; Pupkov, A. S.; Shevnin, E. V.

    2016-09-01

    The influence of hydrogen on the strength and ductility of 30KhGSA and EI659 steels in quasi-static and shock-loading tests was studied experimentally. The sensitivity of the steels to hydrogenation in air under normal pressure or in hydrogen at a pressure of 25 MPa was determined from the results of tests of as-received and pre-hydrogenated samples at a temperature of 773 K and a hydrogen pressure of 50 MPa for 24 h. It is found that EI659 steel doped with tungsten and vanadium is less sensitive to hydrogenation than 30KhGSA steel doped with manganese and chromium.

  19. Study of caffeine as corrosion inhibitors of carbon steel in chloride solution containing hydrogen sulfide using electrochemical impedance spectroscopy (EIS)

    NASA Astrophysics Data System (ADS)

    Solehudin, Agus; Berman, Ega Taqwali; Nurdin, Isdiriayani

    2015-09-01

    The corrosion behaviour of steel surface in the absence and presence of caffeine in 3.5% NaCl solution containing dissolved H2S gas is studied using electrochemical impedance spectroscopy (EIS). The experimental results of carbon steel corrosion in 3.5% NaCl solution containing 500 mg/l H2S at different caffeine concentrations showed that corrosion rate of carbon steel decreases with increasing of caffeine concentrations from 0 to 0,1 mmol/l. Whereas, the corrosion rate increase with increasing of caffeine concentrations from 1 to 10 mmol/l. It is clear that no inhibition efficiency increases with increasing inhibitor concentration. The optimum value of inhibition efficiency was 90% at a caffeine concentration of 0.1 mmol/l. This suggests that caffeine's performance as a corrosion inhibitor is more effective at a concentration of 0.1 mmol/l.

  20. The Performance of Dammar-based Paint System Evaluated by Electrochemical Impedance Spectroscopy (EIS) and Potential Time Measurement (PTM)

    NASA Astrophysics Data System (ADS)

    Omar, N. M.; Ahmad, A. Hanom

    2009-06-01

    The coating resistance of the Dammar-based paint system was determined by using Electrochemical Impedance Spectroscopy (EIS), whereas, the corrosion potential analysis was determined by using potential time measurement (PTM) method. Carotenoid pigment obtained from Capsicum Annum (dried chili pepper) was added into the mixture of dammar and acrylic polyol resin and the paint systems were proofed on Aluminium steel Q-panels as a substrate. Result shows that the paint system with a composition of 35% dammar (CD35%) possessed the higher corrosion resistance after 30 days of exposure in 3% NaCl solution for electrochemical impedance spectroscopy and also can withstand the longest time for delimitation protection in PTM analysis. The results prove that the developed organic paint system can improve the electrochemical and corrosion protection properties of a paint system.

  1. Justifying the Justification Hypothesis: scientific-humanism, Equilintegration (EI) Theory, and the Beliefs, Events, and Values Inventory (BEVI).

    PubMed

    Shealy, Craig N

    2005-01-01

    The Justification Hypothesis (JH; Henriques, 2003) is a basic, general, and macro-level construct that is highly compelling. However, it needs greater specification (i.e., justification) regarding what it is, how it might be operationalized and measured, and what it does and does not predict in the real world. In the present analysis, the act of "justification" is conceptualized as the ongoing attempt to convince self and/or others that one's beliefs and values, which is to say one's "version of reality" or VOR, is correct, defensible, and good. In addressing these issues, this paper is divided into two complementary parts: (a) consideration of justification dynamics and exemplars from a scientific-humanist perspective and (b) an examination of how justification systems and processes have been studied vis-a-vis research and theory on beliefs and values as well as an extant model--Equilintegration (EI) Theory--and method--the Beliefs, Events, and Values Inventory (BEVI).

  2. EIS Behavior of Experimental High-Strength Steel in Near-Neutral pH and Load Conditions

    NASA Astrophysics Data System (ADS)

    Barraza-Fierro, Jesus Israel; Serna-Barquera, Sergio Alonso; Campillo-Illanes, Bernardo Fabian; Castaneda, Homero

    2017-04-01

    Two thermomechanical heat treatments were applied to a high-strength low carbon steel with an experimental chemical composition, and as a result two different microstructures were obtained. Steel A had a ferritic microstructure, and steel B had a bainitic-martensitic one. The corrosion behavior was reviewed at long times in samples without load by means of Electrochemical Impedance Spectroscopy (EIS) in a near-neutral pH (NNpH) environment. The results showed that the quantity and adherence of corrosion products on the sample surface at long times are different. Hence, the impedance was higher for steel B. Slow strain rate testing (SSRT) was applied to tempered samples of the two steels at 473 K, 673 K, and 873 K (200 °C, 400 °C, and 600 °C), and the corrosion behavior was acquired using EIS at the same time as the SSRT in NNpH conditions. This is a novel result because the tension samples were not electrically isolated from the rest of the load frame. The impedance for the ferritic steel was higher than the bainitic-martensitic one, while it slightly decreased for both steel over time. Tempering improved the corrosion resistance for steel A, while it was not modified for steel B. The corrosion behavior could be associated with the susceptibility of these steels to stress corrosion cracking. A transmission line model was proposed to show qualitatively the corrosion behavior of a crack in the steel, if there is a potential profile inside the crack. A hypothetical potential profile was acquired as well as different impedance behaviors based on electrochemical variables.

  3. Comparative Analysis of a Transition Region Bright Point with a Blinker and Coronal Bright Point Using Multiple EIS Emission Lines

    NASA Astrophysics Data System (ADS)

    Orange, N. Brice; Oluseyi, Hakeem M.; Chesny, David L.; Patel, Maulik; Hesterly, Katie; Preuss, Lauren; Neira, Chantale; Turner, Niescja E.

    2014-05-01

    Since their discovery 20 year ago, transition region bright points have never been observed spectroscopically. Bright point properties have not been compared with similar transition region and coronal structures. In this work we have investigated three transient quiet Sun brightenings including a transition region bright point (TR BP), a coronal bright point (CBP) and a blinker. We use time-series observations of the extreme-ultraviolet emission lines of a wide range of temperature T (log T=5.3 - 6.4) from the EUV Imaging Spectrometer (EIS) onboard the Hinode satellite. We present the EIS temperature maps and Doppler maps, which are compared with magnetograms from the Michelson Doppler Imager (MDI) onboard the SOHO satellite. Doppler velocities of the TR BP and blinker are ≤ 25 km s-1, which is typical of transient TR phenomena. The Doppler velocities of the CBP were found to be ≤ 20 km s-1 with exception of those measured at log T=6.2 where a distinct bi-directional jet is observed. From an EM loci analysis we find evidence of single and double isothermal components in the TR BP and CBP, respectively. TR BP and CBP loci curves are characterized by broad distributions suggesting the existence of unresolved structure. By comparing and contrasting the physical characteristics of the events we find that the BP phenomena are an indication of multi-scaled self-similarity, given the similarities in both their underlying magnetic field configuration and evolution in relation to EUV flux changes. In contrast, the blinker phenomena and the TR BP are sufficiently dissimilar in their observed properties as to constitute different event classes. Our work is an indication that the measurement of similar characteristics across multiple event types holds class-predictive power, and is a significant step towards automated solar atmospheric multi-class classification of unresolved transient EUV sources. Finally, the analysis performed here establishes a connection between solar

  4. EIS Behavior of Experimental High-Strength Steel in Near-Neutral pH and Load Conditions

    NASA Astrophysics Data System (ADS)

    Barraza-Fierro, Jesus Israel; Serna-Barquera, Sergio Alonso; Campillo-Illanes, Bernardo Fabian; Castaneda, Homero

    2017-02-01

    Two thermomechanical heat treatments were applied to a high-strength low carbon steel with an experimental chemical composition, and as a result two different microstructures were obtained. Steel A had a ferritic microstructure, and steel B had a bainitic-martensitic one. The corrosion behavior was reviewed at long times in samples without load by means of Electrochemical Impedance Spectroscopy (EIS) in a near-neutral pH (NNpH) environment. The results showed that the quantity and adherence of corrosion products on the sample surface at long times are different. Hence, the impedance was higher for steel B. Slow strain rate testing (SSRT) was applied to tempered samples of the two steels at 473 K, 673 K, and 873 K (200 °C, 400 °C, and 600 °C), and the corrosion behavior was acquired using EIS at the same time as the SSRT in NNpH conditions. This is a novel result because the tension samples were not electrically isolated from the rest of the load frame. The impedance for the ferritic steel was higher than the bainitic-martensitic one, while it slightly decreased for both steel over time. Tempering improved the corrosion resistance for steel A, while it was not modified for steel B. The corrosion behavior could be associated with the susceptibility of these steels to stress corrosion cracking. A transmission line model was proposed to show qualitatively the corrosion behavior of a crack in the steel, if there is a potential profile inside the crack. A hypothetical potential profile was acquired as well as different impedance behaviors based on electrochemical variables.

  5. Integrating Sustainable Development in Higher Education through Experience-Based Learning: Insights from Experts in Team (EiT) for Developing a Combined Theoretical Framework

    ERIC Educational Resources Information Center

    Otte, Pia Piroschka

    2016-01-01

    Universities are understood to play an essential role in the promotion of sustainable development. However, the recognition of sustainable development in higher education poses multiple challenges to the traditional higher education system. This article introduces a course concept called "Experts in Teams" (EiT) as a new platform of…

  6. Studies on the minor constituents of the Caribbean gorgonian octocoral Briareum asbestinum Pallas. Isolation and structure determination of the eunicellin-based diterpenoids briarellins E--I.

    PubMed

    Rodríguez, A D; Cóbar, O M

    1995-11-01

    Five new eunicellin-type diterpenoids, briarellins E--I, along with several known diterpenoids of the asbestinane, briarane and eunicellane classes, were isolated from the Caribbean gorgonian octocoral Briareum asbestinum collected in Puerto Rico. The structures of these compounds were established on the basis of spectroscopic evidence.

  7. Integrating Sustainable Development in Higher Education through Experience-Based Learning: Insights from Experts in Team (EiT) for Developing a Combined Theoretical Framework

    ERIC Educational Resources Information Center

    Otte, Pia Piroschka

    2016-01-01

    Universities are understood to play an essential role in the promotion of sustainable development. However, the recognition of sustainable development in higher education poses multiple challenges to the traditional higher education system. This article introduces a course concept called "Experts in Teams" (EiT) as a new platform of…

  8. 75 FR 44787 - E.I. du Pont de Nemours and Company; Supplemental Notice That Initial Market-Based Rate Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-29

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission E.I. du Pont de Nemours and Company; Supplemental Notice That Initial Market... supplemental notice in the above-referenced proceeding of E. I. du Pont de Nemours and Company's application...

  9. Hinode/EIS Spectroscopic Validation of Very Hot Plasma Imaged with the Solar Dynamics Observatory in Non-flaring Active Region Cores

    NASA Astrophysics Data System (ADS)

    Testa, Paola; Reale, Fabio

    2012-05-01

    We use coronal imaging observations with the Solar Dynamics Observatory/Atmospheric Imaging Assembly (AIA), and Hinode/Extreme-ultraviolet Imaging Spectrometer (EIS) spectral data to explore the potential of narrowband EUV imaging data for diagnosing the presence of hot (T >~ 5 MK) coronal plasma in active regions. We analyze observations of two active regions (AR 11281, AR 11289) with simultaneous AIA imaging and EIS spectral data, including the Ca XVII line (at 192.8 Å), which is one of the few lines in the EIS spectral bands sensitive to hot coronal plasma even outside flares. After careful co-alignment of the imaging and spectral data, we compare the morphology in a three-color image combining the 171, 335, and 94 Å AIA spectral bands, with the image obtained for Ca XVII emission from the analysis of EIS spectra. We find that in the selected active regions the Ca XVII emission is strong only in very limited areas, showing striking similarities with the features bright in the 94 Å (and 335 Å) AIA channels and weak in the 171 Å band. We conclude that AIA imaging observations of the solar corona can be used to track hot plasma (6-8 MK), and so to study its spatial variability and temporal evolution at high spatial and temporal resolution.

  10. DOE/EIS-0355 Remediation of the Moab Uranium Mill Tailings, Grand and San Juan Counties, Utah, Final Environmental Impact Statement (July 2005)

    SciTech Connect

    N /A

    2005-08-05

    The U.S. Department of Energy (DOE or the Department) is proposing to clean up surface contamination and implement a ground water compliance strategy to address contamination that resulted from historical uranium-ore processing at the Moab Uranium Mill Tailings Site (Moab site), Grand County, Utah. Pursuant to the National Environmental Policy Act (NEPA), 42 United States Code (U.S.C.) {section} 4321 et seq., DOE prepared this environmental impact statement (EIS) to assess the potential environmental impacts of remediating the Moab site and vicinity properties (properties where uranium mill tailings were used as construction or fill material before the potential hazards associated with the tailings were known). DOE analyzed the potential environmental impacts of both on-site and off-site remediation and disposal alternatives involving both surface and ground water contamination. DOE also analyzed the No Action alternative as required by NEPA implementing regulations promulgated by the Council on Environmental Quality. DOE has determined that its preferred alternatives are the off-site disposal of the Moab uranium mill tailings pile, combined with active ground water remediation at the Moab site. The preferred off-site disposal location is the Crescent Junction site, and the preferred method of transportation is rail. The basis for this determination is discussed later in this Summary. DOE has entered into agreements with 12 federal, tribal, state, and local agencies to be cooperating agencies in the development and preparation of this EIS. Several of the cooperating agencies have jurisdiction by law and intend to use the EIS to support their own decisionmaking. The others have expertise relevant to potential environmental, social, or economic impacts within their geographic regions. During the preparation of the EIS, DOE met with the cooperating agencies, provided them with opportunities to review preliminary versions of the document, and addressed their comments

  11. Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice.

    PubMed

    Leist, Sarah R; Pilzner, Carolin; van den Brand, Judith M A; Dengler, Leonie; Geffers, Robert; Kuiken, Thijs; Balling, Rudi; Kollmus, Heike; Schughart, Klaus

    2016-02-27

    Influenza A virus is a zoonotic pathogen that poses a major threat to human and animal health. The severe course of influenza infection is not only influenced by viral virulence factors but also by individual differences in the host response. To determine the extent to which the genetic background can modulate severity of an infection, we studied the host responses to influenza infections in the eight genetically highly diverse Collaborative Cross (CC) founder mouse strains. We observed highly divergent host responses between the CC founder strains with respect to survival, body weight loss, hematological parameters in the blood, relative lung weight and viral load. Mouse strain was the main factor with highest effect size on body weight loss after infection, demonstrating that this phenotype was highly heritable. Sex represented another significant main effect, although it was less strong. Analysis of survival rates and mean time to death suggested three groups of susceptibility phenotypes: highly susceptible (A/J, CAST/EiJ, WSB/EiJ), intermediate susceptible (C57BL/6J, 129S1/SvImJ, NOD/ShiLtJ) and highly resistant strains (NZO/HlLtJ, PWK/PhJ). These three susceptibility groups were significantly different with respect to death/survival counts. Viral load was significantly different between susceptible and resistant strains but not between intermediate and highly susceptible strains. CAST/EiJ mice showed a unique phenotype. Despite high viral loads in their lungs, CAST/EiJ mice exhibited low counts of infiltrating granulocytes and showed increased numbers of macrophages in the lung. Histological studies of infected lungs and transcriptome analyses of peripheral blood cells and lungs confirmed an abnormal response in the leukocyte recruitment in CAST/EiJ mice. The eight CC founder strains exhibited a large diversity in their response to influenza infections. Therefore, the CC will represent an ideal mouse genetic reference population to study the influence of

  12. Study of benzotriazole as corrosion inhibitors of carbon steel in chloride solution containing hydrogen sulfide using electrochemical impedance spectroscopy (EIS)

    SciTech Connect

    Solehudin, Agus; Nurdin, Isdiriayani

    2014-03-24

    Corrosion and inhibition studies on API 5LX65 carbon steel in chloride solution containing various concentrations of benzotriazole has been conducted at temperature of 70°C using Electrochemical Impedance Spectroscopy (EIS). Corroded carbon steel surface with and without inhibitor have been observed using X-ray Diffraction (XRD), Scanning Electron Microscope (SEM), and Energy Dispersive Spectroscopy (EDS). The objectives of this research are to study the performance of benzotriazole as corrosion inhibitors. The experimental results of carbon steel corrosion in 3.5% NaCl solution containing 500 mg/l H{sub 2}S at different BTAH concentrations showed that corrosion rate of carbon steel decreases with increasing of BTAH concentrations from 0 to 10 mmol/l. The inhibition efficiency of BTAH was found to be affected by its concentration. The optimum efficiency obtained of BTAH is 93% at concentration of 5 mmol/l. The result of XRD and EDS analysis reveal the iron sulfide (FeS) formation on corroded carbon steel surface without inhibitor. The EDS spectrum show the Nitrogen (N) bond on carbon steel surface inhibited by BTAH.

  13. Energy Return on Energy Invested (ERoEI) for photovoltaic solar systems in regions of moderate insolation: A comprehensive response

    DOE PAGES

    Raugei, Marco; Sgouridis, Sgouris; Murphy, David; ...

    2017-01-01

    A recent paper by Ferroni and Hopkirk (2016) asserts that the ERoEI (also referred to as EROI) of photovoltaic (PV) systems is so low that they actually act as net energy sinks, rather than delivering energy to society. Such claim, if accurate, would call into question many energy investment decisions. In the same paper, a comparison is also drawn between PV and nuclear electricity. We have carefully analysed this paper, and found methodological inconsistencies and calculation errors that, in combination, render its conclusions not scientifically sound. Ferroni and Hopkirk adopt 'extended' boundaries for their analysis of PV without acknowledging thatmore » such choice of boundaries makes their results incompatible with those for all other technologies that have been analysed using more conventional boundaries, including nuclear energy with which the authors engage in multiple inconsistent comparisons. In addition, they use out-dated information, make invalid assumptions on PV specifications and other key parameters, and conduct calculation errors, including double counting. Here in this paper, we provide revised EROI calculations for PV electricity in Switzerland, adopting both conventional and 'extended' system boundaries, to contrast with their results, which points to an order-of-magnitude underestimate of the EROI of PV in Switzerland by Ferroni and Hopkirk.« less

  14. Energy Return on Energy Invested (ERoEI) for photovoltaic solar systems in regions of moderate insolation: A comprehensive response

    SciTech Connect

    Raugei, Marco; Sgouridis, Sgouris; Murphy, David; Fthenakis, Vasilis; Frischknecht, Rolf; Breyer, Christian; Bardi, Ugo; Barnhart, Charles; Buckley, Alastair; Carbajales-Dale, Michael; Csala, Denes; de Wild-Scholten, Mariska; Heath, Garvin; Jæger-Waldau, Arnulf; Jones, Christopher; Keller, Arthur; Leccisi, Enrica; Mancarella, Pierluigi; Pearsall, Nicola; Siegel, Adam; Sinke, Wim; Stolz, Philippe

    2017-01-01

    A recent paper by Ferroni and Hopkirk (2016) asserts that the ERoEI (also referred to as EROI) of photovoltaic (PV) systems is so low that they actually act as net energy sinks, rather than delivering energy to society. Such claim, if accurate, would call into question many energy investment decisions. In the same paper, a comparison is also drawn between PV and nuclear electricity. We have carefully analysed this paper, and found methodological inconsistencies and calculation errors that, in combination, render its conclusions not scientifically sound. Ferroni and Hopkirk adopt 'extended' boundaries for their analysis of PV without acknowledging that such choice of boundaries makes their results incompatible with those for all other technologies that have been analysed using more conventional boundaries, including nuclear energy with which the authors engage in multiple inconsistent comparisons. In addition, they use out-dated information, make invalid assumptions on PV specifications and other key parameters, and conduct calculation errors, including double counting. Here in this paper, we provide revised EROI calculations for PV electricity in Switzerland, adopting both conventional and 'extended' system boundaries, to contrast with their results, which points to an order-of-magnitude underestimate of the EROI of PV in Switzerland by Ferroni and Hopkirk.

  15. Free fatty acid profiling of marine sentinels by nanoLC-EI-MS for the assessment of environmental pollution effects.

    PubMed

    Albergamo, Ambrogina; Rigano, Francesca; Purcaro, Giorgia; Mauceri, Angela; Fasulo, Salvatore; Mondello, Luigi

    2016-11-15

    The present work aims to elucidate the free fatty acid (FFA) profile of the mussel Mytilus galloprovincialis caged in an anthropogenically impacted area and in a reference site through an innovative and validated analytical approach for the assessment of biological alterations induced by marine pollution. The FFA pattern is involved in the regulation of different cellular pathways and differs with respect to metabolic stimuli. To this purpose, the lipid fraction of mussels coming from both sampling areas was extracted and the FFA fractions were isolated and purified by a solid phase extraction; then, nano-scale liquid chromatography coupled to electron ionization mass spectrometry (nanoLC-EI-MS) was employed for the characterization of the two samples. A total of 19 and 17 FFAs were reliably identified in the mussels coming from the reference and polluted site, respectively. Significant qualitative and quantitative differences found in saturated, monounsaturated and polyunsaturated species may be exploited as typical pollution biomarkers (e.g. alteration of the fatty acid biosynthetic system and lipotoxicity) and explain adverse and compromising effects (e.g. oxidative stress and inflammatory processes) related to environmental pollution. Copyright © 2016 Elsevier B.V. All rights reserved.

  16. Raman and EIS characterizations of interfacial compounds due to iodides reactions in dye-sensitized solar cells (DSSC)

    NASA Astrophysics Data System (ADS)

    Bernard, Marie-Claude; Cachet, Hubert; Falaras, Polycarpos; Hugot-Le Goff, Anne; Oanh, N. T. T.; Stergiopoulos, Thomas

    2003-02-01

    Raman spectroscopy (RS) was used to study the interfacial species due to the presence of a redox couple in the electrolyte during the operation of dye-sensitized solar cells (DSSC). Two bands appear in the Raman spectra of polypyridinium (ppy) dyes adsorbed on nanocrystalline anatase. They can be directly connected to the presence of iodine/iodide couple because they are not present when hydroquinone/quinone (HQ/Q) redox couple is used. The band at 112 cm-1 has already be assigned to the presence of tri-iodide; it disappears only at very high cathodic polarization. The band at 167 cm-1 is due to the formation of an intermediate compound between the oxidized form of the dye , D+, and iodine; it involves a Py-I bonding. The use of different focusing proves that this compound is located below the adsorbed tri-iodide. Electrochemical Impedance Spectroscopy (EIS) allows to determine the charge transfer kinetics at the three main interfaces of the cell and to characterize the diffusion of tri-iodide species. Three different cell functioning regimes (photocurrent plateau, recombination, accumulation) were described. The Raman intensities of the two iodide-connected bands are investigated in each of the three regimes. The "Py-I" band is strong in the photocurrent plateau range and disappears in the recombination range.

  17. Alfvén Wave Heating Model of an Active Region and Comparisons with the EIS Observations

    NASA Astrophysics Data System (ADS)

    Lawless, A. P.; Asgari-Targhi, M.

    2013-12-01

    We study the generation and dissipation of Alfvén waves in open and closed field lines using the images from the Solar Dynamics Observatory's (SDO) Atmospheric Imaging Assembly (AIA) (van Ballegouijen et al. 2011; Asgari-Targhi & van Ballegouijen 2012; Asgari et al. 2013). The goal is to search for observational evidence of Alfvén waves in the solar corona and to understand their role in coronal heating. We focus on one particular active region on the 10th of December 2007. Using the MDI magnetogram and the potential field modeling of this region, we create three-dimensional MHD models for several open and closed field lines in different locations in the active region. For each model, we compute the temperature, pressure, magnetic field strength, average heating rate, and other parameters along the loop. We then compare these results with the EIS observations. This research is supported by the NSF grant for the Solar physics REU Program at the Smithsonian Astrophysical Observatory (AGS-1263241) and contract SP02H1701R from Lockheed-Martin to SAO.

  18. Chromospherically active stars. III - HD 26337 = EI Eri: An RS CVn candidate for the Doppler-imaging technique

    NASA Technical Reports Server (NTRS)

    Fekel, Francis C.; Quigley, Robert; Gillies, Kim; Africano, John L.

    1987-01-01

    Spectroscopic observations of the chromospherically active G5 IV single-lined binary HD 26337 = EI Eri are presented. An orbital period of 1.94722 days is found for the star. It has moderately strong Ca II H and K emission and strong ultraviolet emission features, while H-alpha is a weak absorption feature that is variable in strength. The inclination of the system is 46 + or - 12 deg, and the unseen secondary is probably a late K or early M dwarf. The v sin i of the primary is 50 + or - 3 km/s, resulting in a minimum radius of 1.9 + or - 0.1 solar radius. The star is within the required limits for Doppler imaging. The primary is close to filling its Roche lobe, resulting in a strong constraint that the mass ratio is 2.6 or greater, with a primary mass of at least 1.4 solar mass. The distance to the system is estimated at 75 pc.

  19. Multi-wall carbon nanotubes (MWCNTs)-doped polypyrrole DNA biosensor for label-free detection of genetically modified organisms by QCM and EIS.

    PubMed

    Truong, Thi Ngoc Lien; Tran, Dai Lam; Vu, Thi Hong An; Tran, Vinh Hoang; Duong, Tuan Quang; Dinh, Quang Khieu; Tsukahara, Toshifumi; Lee, Young Hoon; Kim, Jong Seung

    2010-01-15

    In this paper, we describe DNA electrochemical detection for genetically modified organism (GMO) based on multi-wall carbon nanotubes (MWCNTs)-doped polypyrrole (PPy). DNA hybridization is studied by quartz crystal microbalance (QCM) and electrochemical impedance spectroscopy (EIS). An increase in DNA complementary target concentration results in a decrease in the faradic charge transfer resistance (R(ct)) and signifying "signal-on" behavior of MWCNTs-PPy-DNA system. QCM and EIS data indicated that the electroanalytical MWCNTs-PPy films were highly sensitive (as low as 4pM of target can be detected with QCM technique). In principle, this system can be suitable not only for DNA but also for protein biosensor construction.

  20. First analysis of eight Algol-type binaries: EI Aur, XY Dra, BP Dra, DD Her, VX Lac, WX Lib, RZ Lyn, and TY Tri

    NASA Astrophysics Data System (ADS)

    Zasche, P.

    2016-01-01

    The available photometry from the online databases were used for the first light curve analysis of eight eclipsing binary systems EI Aur, XY Dra, BP Dra, DD Her, VX Lac, WX Lib, RZ Lyn, and TY Tri. All these stars are of Algol-type, having the detached components and the orbital periods from 0.92 to 6.8 days. For the systems EI Aur and BP Dra the large amount of the third light was detected during the light curve solution. Moreover, 468 new times of minima for these binaries were derived, trying to identify the period variations. For the systems XY Dra and VX Lac the third bodies were detected with the periods 17.7, and 49.3 years, respectively.

  1. Neon-like Iron Ion Lines Measured in NIFS/Large Helical Device (LHD) and Hinode/EUV Imaging Spectrometer (EIS)

    NASA Astrophysics Data System (ADS)

    Watanabe, Tetsuya; Hara, Hirohisa; Murakami, Izumi; Kato, Daiji; Sakaue, Hiroyuki A.; Morita, Shigeru; Suzuki, Chihiro; Tamura, Naoki; Yamamoto, Norimasa; Nakamura, Nobuyuki

    2017-06-01

    Line intensities emerging from the Ne-sequence iron ion (Fe XVII) are measured in the laboratory, by the Large Helical Device at the National Institute for Fusion Science, and in the solar corona by the EUV Imaging Spectrometer (EIS) on board the Hinode mission. The intensity ratios of Fe XVII λ 204.6/λ 254.8 are derived in the laboratory by unblending the contributions of the Fe XIII and XII line intensities. They are consistent with theoretical predictions and solar observations, the latter of which endorses the in-flight radiometric calibrations of the EIS instrument. The still remaining temperature-dependent behavior of the line ratio suggests the contamination of lower-temperature iron lines that are blended with the λ 204.6 line.

  2. Determination of the transient period of the EIS complex and investigation of the suppression of blood glucose levels by L-arabinose in healthy adults.

    PubMed

    Shibanuma, Kiyoshi; Degawa, Yoko; Houda, Koichi

    2011-09-01

    L-Arabinose uncompetitively inhibits intestinal sucrase by forming an enzyme-inhibitor-substrate (EIS) complex. The transient period of the EIS complex affects the time span of inhibition. We determined the apparent transient period of the EIS complex of sucrase, L-arabinose, and sucrose both in vitro and in humans. Intestinal acetone powder (a source of sucrase), L-arabinose, and sucrose were mixed and injected into a dialysis membrane that was placed in a sucrose solution. The production rate of D-glucose and the release rate of L-arabinose from sucrase were determined. We also investigated the suppression of blood glucose levels by L-arabinose in 21 healthy volunteers. Sucrose (40 g) was ingested with or without L-arabinose (2 g), then blood glucose values were measured, which returned to steady-state conditions within 2 h. Volunteers were then given 90 g of commercial adzuki bean jelly containing 40 g sucrose as the sucrose load, and blood glucose values were measured again. Addition of L-arabinose reduced the production rate of D -glucose compared to the rates measured in the absence of L-arabinose for several hours in vitro. L-Arabinose was released at a lower rate in the presence of sucrose than in its absence. Blood glucose values measured 2 h after sucrose was given with L -arabinose were significantly lower than those measured when L-arabinose was not given (Δ change in maximum value: with L-arabinose, 53.8 ± 19.7 mg/dL; without L-arabinose, 65.0 ± 17.7 mg/dL). The EIS complex of sucrase-L -arabinose-sucrose was maintained for several hours both in vitro and in humans.

  3. Impact of gyrB and eis Mutations in Improving Detection of Second-Line-Drug Resistance among Mycobacterium tuberculosis Isolates from Georgia.

    PubMed

    Bablishvili, N; Tukvadze, N; Shashkina, E; Mathema, B; Gandhi, N R; Blumberg, H M; Kempker, R R

    2017-09-01

    The country of Georgia has a high burden of multi- and extensively drug-resistant tuberculosis (XDR-TB). To evaluate whether mutations in gyrB and eis genes increased the sensitivity of detection of phenotypic resistance to ofloxacin and kanamycin or capreomycin compared to use of the first-generation MTBDRsl assay alone, which tests for mutations in gyrA and rrs genes, a retrospective study of stored Mycobacterium tuberculosis isolates was performed. All isolates underwent DNA sequencing of resistance-determining regions. Among 112 M. tuberculosis isolates with DNA extraction data, targeted sequencing was successfully performed for each gene as follows: for gyrA, 98% sensitivity; for gyrB, 96%; for rrs, 93%; for the eis gene and its promoter, 93%. The specificity and hence the positive predictive value of gyrA and gyrB mutations for detecting ofloxacin resistance were 100%. The addition of gyrB mutations increased the sensitivity of phenotypic ofloxacin resistance detection by 13% (75% to 88%). All rrs resistance-conferring mutations were A1401G, and this mutation had low sensitivity (40% and 18%) and high specificity (95% and 100%) in predicting phenotypic capreomycin and kanamycin resistance, respectively. The eis C-14T mutation increased the sensitivity of phenotypic kanamycin resistance detection by 9% (18% to 27%) and was found solely in kanamycin phenotypic resistance isolates. Our data showed that the inclusion of eis C-14T and gyrB mutations in addition to rrs and gyrA mutations improves the sensitivity of detection of phenotypic ofloxacin and kanamycin resistance, respectively. Copyright © 2017 American Society for Microbiology.

  4. SIMULTANEOUS IRIS AND HINODE/EIS OBSERVATIONS AND MODELING OF THE 2014 OCTOBER 27 X2.0 CLASS FLARE

    SciTech Connect

    Polito, V.; Reep, J. W.; Del Zanna, G.; Mason, H. E.; Reeves, K. K.; Golub, L.; Simões, P. J. A.; Dudík, J.

    2016-01-10

    We present a study of the X2-class flare which occurred on 2014 October 27 and was observed with the Interface Region Imaging Spectrograph (IRIS) and the EUV Imaging Spectrometer (EIS) on board the Hinode satellite. Thanks to the high cadence and spatial resolution of the IRIS and EIS instruments, we are able to compare simultaneous observations of the Fe xxi 1354.08 Å and Fe xxiii 263.77 Å high-temperature emission (≳10 MK) in the flare ribbon during the chromospheric evaporation phase. We find that IRIS observes completely blueshifted Fe xxi line profiles, up to 200 km s{sup −1} during the rise phase of the flare, indicating that the site of the plasma upflows is resolved by IRIS. In contrast, the Fe xxiii line is often asymmetric, which we interpret as being due to the lower spatial resolution of EIS. Temperature estimates from SDO/AIA and Hinode/XRT show that hot emission (log(T[K]) > 7.2) is first concentrated at the footpoints before filling the loops. Density-sensitive lines from IRIS and EIS give estimates of electron number density of ≳10{sup 12} cm{sup −3} in the transition region lines and 10{sup 10} cm{sup −3} in the coronal lines during the impulsive phase. In order to compare the observational results against theoretical predictions, we have run a simulation of a flare loop undergoing heating using the HYDRAD 1D hydro code. We find that the simulated plasma parameters are close to the observed values that are obtained with IRIS, Hinode, and AIA. These results support an electron beam heating model rather than a purely thermal conduction model as the driving mechanism for this flare.

  5. Isomeric discrimination of synthetic cannabinoids by GC-EI-MS: 1-adamantyl and 2-adamantyl isomers of N-adamantyl carboxamides.

    PubMed

    Asada, Akiko; Doi, Takahiro; Tagami, Takaomi; Takeda, Akihiro; Sawabe, Yoshiyuki

    2017-03-01

    N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide (APINACA) and N-(1-adamantyl)-1-pentyl-1H-indole-3-carboxamide (APICA) are carboxamide-type synthetic cannabinoids comprising indazole/indole-3-carboxylic acid and adamantan-1-amine moieties. However, in the case of compounds like APINACA or APICA, adamantyl positional isomers exist, wherein either adamantan-1-amine or adamantan-2-amine is present. These adamantyl positional isomers have not been reported in previous studies, and no analytical data are available. To avoid misidentification of adamantyl carboxamide-type synthetic cannabinoids, it is important to develop methods to discriminate these adamantyl positional isomers. In this study, we report the analytical characterization by gas chromatography-electron ionization-mass spectrometry (GC-EI-MS). For providing analytical standards, we synthesized eight carboxamide-type synthetic cannabinoids (APINACA 2-adamantyl isomer, APICA 2-adamantyl isomer, 5 F-APINACA 2-adamantyl isomer, 5 F-APICA 2-adamantyl isomer, 5Cl-APINACA, 5Cl-APINACA 2-adamantyl isomer, adamantyl-THPINACA, 2-adamantyl-THPINACA) and purchased four 1-adamantyl derivatives (APINACA, APICA, 5 F-APINACA, 5 F-APICA). Although the retention times of the isomers are similar, 1-adamantyl carboxamides can be clearly discriminated from their 2-adamantyl isomers based on their different fragmentation patterns in the EI-MS spectra. Specifically, EI-MS spectra for adamantylindazole carboxamides showed remarkable differences between the 1-adamantyl and 2-adamantyl isomers. On the other hand, EI-MS spectra for adamantylindole carboxamides were similar, but the diagnostic ions of the 2-adamantyl isomers were observed. The method described herein was applicable to all compounds tested in this study and is expected to be of use for isomeric differentiation between other untested adamantyl carboxamide-type synthetic cannabinoids. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley

  6. Comparing the accuracy of ES-BC, EIS-GS, and ES Oxi on body composition, autonomic nervous system activity, and cardiac output to standardized assessments

    PubMed Central

    Lewis, John E; Tannenbaum, Stacey L; Gao, Jinrun; Melillo, Angelica B; Long, Evan G; Alonso, Yaima; Konefal, Janet; Woolger, Judi M; Leonard, Susanna; Singh, Prabjot K; Chen, Lawrence; Tiozzo, Eduard

    2011-01-01

    Background and purpose The Electro Sensor Complex (ESC) is software that combines three devices using bioelectrical impedance, galvanic skin response, and spectrophotometry: (1) ES-BC (Electro Sensor-Body Composition; LD Technology, Miami, FL) to assess body composition, (2) EIS-GS (Electro Interstitial Scan-Galvanic Skin; LD Technology) to predict autonomic nervous system activity, and (3) ES Oxi (Electro Sensor Oxi; LD Technology) to assess cardiac output. The objective of this study was to compare each to a standardized assessment: ES-BC to dual-energy X-ray absorptiometry (DXA), EIS-GS to heart rate variability, and ES Oxi to BioZ Dx Diagnostic System (BioZ Dx; SonoSite Inc, Bothell, WA). Patients and methods The study was conducted in two waves. Fifty subjects were assessed for body composition and autonomic nervous system activity. Fifty-one subjects were assessed for cardiac output. Results We found adequate relative and absolute agreement between ES-BC and DXA for fat mass (r = 0.97, P < 0.001) with ES-BC overestimating fat mass by 0.1 kg and for body fat percentage (r = 0.92, P < 0.001) with overestimation of fat percentage by 0.4%. For autonomic nervous system activity, we found marginal relative agreement between EIS-GS and heart rate variability by using EIS-GS as the predictor in a linear regression equation (adjusted R2 = 0.56, P = 0.03). For cardiac output, adequate relative and absolute agreement was found between ES Oxi and BioZ Dx at baseline (r = 0.60, P < 0.001), after the first exercise stage (r = 0.79, P < 0.001), and after the second exercise stage (r = 0.86, P < 0.001). Absolute agreement was found at baseline and after both bouts of exercise; ES Oxi overestimated baseline and stage 1 exercise cardiac output by 0.3 L/minute and 0.1 L/minute, respectively, but exactly estimated stage 2 exercise cardiac output. Conclusion ES-BC and ES Oxi accurately assessed body composition and cardiac output compared to standardized instruments, whereas EIS

  7. Permanent Draft Genome Sequence for Frankia sp. Strain EI5c, a Single-Spore Isolate of a Nitrogen-Fixing Actinobacterium, Isolated from the Root Nodules of Elaeagnus angustifolia

    PubMed Central

    D’Angelo, Timothy; Oshone, Rediet; Abebe-Akele, Feseha; Simpson, Stephen; Morris, Krystalynne; Thomas, W. Kelley

    2016-01-01

    Frankia sp. strain EI5c is a member of Frankia lineage III, which is able to reinfect plants of the Eleagnaceae, Rhamnaceae, Myricaceae, and Gymnostoma, as well as the genus Alnus. Here, we report the 6.6-Mbp draft genome sequence of Frankia sp. strain EI5c with a G+C content of 72.14 % and 5,458 candidate protein-encoding genes. PMID:27389275

  8. Permanent Draft Genome Sequence for Frankia sp. Strain EI5c, a Single-Spore Isolate of a Nitrogen-Fixing Actinobacterium, Isolated from the Root Nodules of Elaeagnus angustifolia.

    PubMed

    D'Angelo, Timothy; Oshone, Rediet; Abebe-Akele, Feseha; Simpson, Stephen; Morris, Krystalynne; Thomas, W Kelley; Tisa, Louis S

    2016-07-07

    Frankia sp. strain EI5c is a member of Frankia lineage III, which is able to reinfect plants of the Eleagnaceae, Rhamnaceae, Myricaceae, and Gymnostoma, as well as the genus Alnus Here, we report the 6.6-Mbp draft genome sequence of Frankia sp. strain EI5c with a G+C content of 72.14 % and 5,458 candidate protein-encoding genes.

  9. CON4EI: Short Time Exposure (STE) test method for hazard identification and labelling of eye irritating chemicals.

    PubMed

    Adriaens, E; Willoughby, J A; Meyer, B R; Blakeman, L C; Alépée, N; Fochtman, P; Guest, R; Kandarova, H; Verstraelen, S; Van Rompay, A R

    2017-08-09

    Assessment of ocular irritancy is an international regulatory requirement in the safety evaluation of industrial and consumer products. Although many in vitro ocular irritation assays exist, alone they are incapable of fully categorizing chemicals. Therefore, the CEFIC-LRI-AIMT6-VITO CON4EI consortium was developed to assess the reliability of eight in vitro test methods and establish an optimal tiered-testing strategy. One assay selected was the Short Time Exposure (STE) assay. This assay measures the viability of SIRC rabbit corneal cells after 5min exposure to 5% and 0.05% solutions of test material, and is capable of categorizing of Category 1 and No Category chemicals. The accuracy of the STE test method to identify Cat 1 chemicals was 61.3% with 23.7% sensitivity and 95.2% specificity. If non-soluble chemicals and unqualified results were excluded, the performance to identify Cat 1 chemicals remained similar (accuracy 62.2% with 22.7% sensitivity and 100% specificity). The accuracy of the STE test method to identify No Cat chemicals was 72.5% with 66.2% sensitivity and 100% specificity. Excluding highly volatile chemicals, non-surfactant solids and non-qualified results resulted in an important improvement of the performance of the STE test method (accuracy 96.2% with 81.8% sensitivity and 100% specificity). Furthermore, it seems that solids are more difficult to test in the STE, 71.4% of the solids resulted in unqualified results (solubility issues and/or high variation between independent runs) whereas for liquids 13.2% of the results were not qualified, supporting the restriction of the test method regarding the testing of solids. Copyright © 2017. Published by Elsevier Ltd.

  10. YBR/EiJ mice: a new model of glaucoma caused by genes on chromosomes 4 and 17

    PubMed Central

    Nair, K. Saidas; Cosma, Mihai; Raghupathy, Narayanan; Sellarole, Michael A.; Tolman, Nicholas G.; de Vries, Wilhelmine; Smith, Richard S.

    2016-01-01

    ABSTRACT A variety of inherited animal models with different genetic causes and distinct genetic backgrounds are needed to help dissect the complex genetic etiology of glaucoma. The scarcity of such animal models has hampered progress in glaucoma research. Here, we introduce a new inherited glaucoma model: the inbred mouse strain YBR/EiJ (YBR). YBR mice develop a form of pigmentary glaucoma. They exhibit a progressive age-related pigment-dispersing iris disease characterized by iris stromal atrophy. Subsequently, these mice develop elevated intraocular pressure (IOP) and glaucoma. Genetic mapping studies utilizing YBR as a glaucoma-susceptible strain and C57BL/6J as a glaucoma-resistant strain were performed to identify genetic loci responsible for the iris disease and high IOP. A recessive locus linked to Tyrp1b on chromosome 4 contributes to iris stromal atrophy and high IOP. However, this is not the only important locus. A recessive locus on YBR chromosome 17 causes high IOP independent of the iris stromal atrophy. In specific eyes with high IOP caused by YBR chromosome 17, the drainage angle (through which ocular fluid leaves the eye) is largely open. The YBR alleles of genes on chromosomes 4 and 17 underlie the development of high IOP and glaucoma but do so through independent mechanisms. Together, these two loci act in an additive manner to increase the susceptibility of YBR mice to the development of high IOP. The chromosome 17 locus is important not only because it causes IOP elevation in mice with largely open drainage angles but also because it exacerbates IOP elevation and glaucoma induced by pigment dispersion. Therefore, YBR mice are a valuable resource for studying the genetic etiology of IOP elevation and glaucoma, as well as for testing new treatments. PMID:27483353

  11. EI Handbook. Third Edition.

    ERIC Educational Resources Information Center

    Education International, Brussels (Belgium).

    This booklet presents information on Education International, a group that promotes teacher rights, trade union rights (including teacher unions), fair teaching conditions, and equal education for all people. The booklet includes information on the following: the Education International executive board (name, address, telephone, fax, and e-mail);…

  12. Diagnostics of a Coronal Hole and the Adjacent Quiet Sun by The Hinode/EUV Imaging Spectrometer (EIS)

    NASA Astrophysics Data System (ADS)

    Kayshap, P.; Banerjee, D.; Srivastava, A. K.

    2015-10-01

    A comparison between a coronal hole (CH) and the adjacent quiet Sun (QS) has been performed using the spectroscopic diagnostics of the Hinode/EUV Imaging Spectrometer (EIS). Based on spectral signatures, we identify the coronal funnels that play an important role in the formation and propagation of the nascent fast solar wind. From the observed line profiles, we estimate the intensity, Doppler velocity, line width (FWHM), and electron density over CH and the adjacent QS region of a north polar coronal hole (NPCH). Excess-width regions (excess FWHM above a threshold level) have been identified in QS and CH. The plasma-flow inversion (average red-shifts changing to blue-shifts at a specific height) in CH and excess-width regions of QS take place at {≈} 5.01×105K. Furthermore, the high electron-density concentration in excess-width regions of QS provides an indication that these regions are the footprints of coronal funnels. We also find that non-thermal velocities of CH are higher in comparison to QS indicating that the CHs are the source regions of the fast solar wind. Doppler and non-thermal velocities, as recorded by different-temperature lines, have also been compared with previously published results. As we go from lower to the upper solar atmosphere, down-flows are dominant in the lower atmosphere, while coronal lines are dominated by up-flows with a maximum value of ≈ 10 - 12 km s-1 in QS. The non-thermal velocity increases first but after log Te = 5.47 it decreases further in QS. This trend can be interpreted as a signature of the dissipation of Alfvén waves, while an increasing trend reported earlier may be attributed to the signature of the growth of Alfvén waves at lower heights. The predominance of the occurrence of nano-flares around the O vi formation temperature could also explain the non-thermal-velocity trend.

  13. Synthesis of 81Br-labeled polybrominated diphenyl ethers and their characterization using GC(EI)MS and GC(ICP)MS.

    PubMed

    González-Gago, Adriana; Marchante-Gayón, Juan Manuel; Ferrero, Miguel; Garcia Alonso, J Ignacio

    2010-04-01

    A mixture of different (81)Br-labeled polybrominated diphenyl ethers (PBDEs) was prepared and characterized for its future use as spike for the isotope dilution analysis of PBDEs. The synthesis was carried out by direct bromination of diphenyl ether using (81)Br enriched Br(2) obtained after aqueous oxidation of bromide with potassium peroxymonosulfate and extraction into dichloromethane. The number of bromine atoms introduced in the diphenyl ether molecule depended on the molar ratio between bromine and diphenyl ether. The final mixture prepared contained a mixture of tri-, tetra-, penta-, and hexabrominated PBDEs with a larger concentration of the tetrabrominated congener BDE-47. The isotopic composition of bromine in the resulting PBDEs mixture was determined by GC(ICP)MS and resulted in a 99.53% enrichment of the isotope 81 of bromine. The concentration of three of the PBDE congeners (28, 47, and 99) in the mixture was determined by reverse isotope dilution analysis using a certified, natural abundance, PBDEs mixture and both GC(ICP)MS and GC(EI)MS. For this purpose, the fragmentation and isotope distribution patterns of the different PBDE cogeners in the positive electron ionization source were studied in detail both for natural abundance and labeled compounds. A procedure based on isotope pattern deconvolution was developed which allowed the direct determination of the concentration of the labeled PBDEs in the spike mixture by GC(EI)MS. Finally, the GC(EI)MS isotope pattern deconvolution procedure was applied for the determination of natural abundance congeners 28, 47, and 99 in spiked waters at ng L(-1) levels. Detection limits below 0.5 ng L(-1) could be obtained for all compounds using only 100 mL of sample and liquid-liquid extraction with isooctane.

  14. Enhancement of electrochemical performances for LiFePO4/C with 3D-grape-bunch structure and selection of suitable equivalent circuit for fitting EIS results

    NASA Astrophysics Data System (ADS)

    Li, Xiangfeng; Luo, Dongmei; Zhang, Xin; Zhang, Zhao

    2015-09-01

    The LiFePO4/C composite with 3D-grape-bunch structure is successfully synthesized through a novel hydrothermal method. Sucrose is used as in-situ coating carbon source, and the hydroxylated MWCNTs are used as connecting carbon wires which can be embedded into the carbon coating via self-assembling of the hydrophilic groups to form 3D-grape-bunch structure. The influences of the 3D-grape-bunch structure on the morphology, structure and electrochemical performance of the LiFePO4/C composites are investigated by XRD, SEM, TEM, BET, galvanostatic charge/discharge tests, electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV) tests. Especially, four kinds of the equivalent circuit models usually employed to analysis the EISs of LiFePO4 as cathode material for Li-ion battery are discussed, and the suitable equivalent circuit for fitting EIS of LiFePO4/C composite with 3D-grape-bunch structure is selected. The optimal LiFePO4/C composite with 3D-grape-bunch structure owing to its good conductive network and high graphitic degree (low ID/IG value) of residual carbon exhibits a stable and high reversible capacity of 160.5 mAh g-1 at 0.1C and 108.4 mAh g-1 even at 10.0C, and the cycling capacity retention rate reaches 99.9% over 60 cycles. Moreover, it also exhibits high conductivity, good reversibility and excellent stability in EIS and CV tests.

  15. MULTI-WAVELENGTH OBSERVATIONS OF SUPERNOVA 2011ei: TIME-DEPENDENT CLASSIFICATION OF TYPE IIb AND Ib SUPERNOVAE AND IMPLICATIONS FOR THEIR PROGENITORS

    SciTech Connect

    Milisavljevic, Dan; Margutti, Raffaella; Soderberg, Alicia M.; Chomiuk, Laura; Sanders, Nathan E.; Pignata, Giuliano; Bufano, Filomena; Fesen, Robert A.; Parrent, Jerod T.; Parker, Stuart; Mazzali, Paolo; Pian, Elena; Pickering, Timothy; Buckley, David A. H.; Crawford, Steven M.; Gulbis, Amanda A. S.; Hettlage, Christian; Hooper, Eric; Nordsieck, Kenneth H.; O'Donoghue, Darragh; and others

    2013-04-10

    We present X-ray, UV/optical, and radio observations of the stripped-envelope, core-collapse supernova (SN) 2011ei, one of the least luminous SNe IIb or Ib observed to date. Our observations begin with a discovery within {approx}1 day of explosion and span several months afterward. Early optical spectra exhibit broad, Type II-like hydrogen Balmer profiles that subside rapidly and are replaced by Type Ib-like He-rich features on a timescale of one week. High-cadence monitoring of this transition suggests absorption attributable to a high-velocity ({approx}> 12, 000 km s{sup -1}) H-rich shell, which is likely present in many Type Ib events. Radio observations imply a shock velocity of v Almost-Equal-To 0.13 c and a progenitor star average mass-loss rate of M-dot {approx}1.4 Multiplication-Sign 10{sup -5} M{sub sun} yr{sup -1} (assuming wind velocity v{sub w} = 10{sup 3} km s{sup -1}). This is consistent with independent constraints from deep X-ray observations with Swift-XRT and Chandra. Overall, the multi-wavelength properties of SN 2011ei are consistent with the explosion of a lower-mass (3-4 M{sub Sun }), compact (R{sub *} {approx}< 1 Multiplication-Sign 10{sup 11} cm), He-core star. The star retained a thin hydrogen envelope at the time of explosion, and was embedded in an inhomogeneous circumstellar wind suggestive of modest episodic mass loss. We conclude that SN 2011ei's rapid spectral metamorphosis is indicative of time-dependent classifications that bias estimates of the relative explosion rates for Type IIb and Ib objects, and that important information about a progenitor star's evolutionary state and mass loss immediately prior to SN explosion can be inferred from timely multi-wavelength observations.

  16. Sediment Studies Refute EIS Hypothesis, While Most Fundamental Process Questions Remain Unanswered: An Update on Experiments in Grand Canyon

    NASA Astrophysics Data System (ADS)

    Melis, T. S.; Topping, D. J.; Wright, S. A.; Rubin, D. M.; Schmidt, J. C.; Hazel, J. E.; Kaplinski, M. A.; Parnell, R. A.

    2004-12-01

    drought throughout the Upper Colorado River Basin now poses a natural barrier to testing the key sediment hypothesis. Downstream sand production from the Paria River remains at its lowest level in 80 years, while water storage in Lake Powell approaches 40 percent of capacity. As scientists wait out delays in sediment experimentation forced by the current drought, managers have already approved limited sediment augmentation feasibility studies aimed at identifying options for managing physical habitats. With regard to conventional thinking about regulation and management of natural hydrologic systems, some important lessons may be learned from the current situation. Rubin, D.M., Topping, D.J., Schmidt, J.C., Hazel, J., Kaplinski, M. and Melis, T.S., 2002, Recent Sediment Studies Refute Glen Canyon Dam EIS Hypothesis: Eos, vol. 83, no. 25, p. 273-278. Laursen, E.M., Ince, S. and Pollack, J., 1976, On Sediment Transport Through the Grand Canyon, Proceedings of the 3rd Federal Interagency Sedimentation Conference, Denver, CO, vol. 1, p. 4-76 - 4-87.

  17. Liquid chromatography-electron ionization tandem mass spectrometry with the Direct-EI interface in the fast determination of diazepam and flunitrazepam in alcoholic beverages.

    PubMed

    Famiglini, Giorgio; Termopoli, Veronica; Palma, Pierangela; Cappiello, Achille

    2016-04-01

    This is the first application based on electron ionization (EI) using a Direct-EI LC interface and MS/MS to detect unequivocally target compounds in a very small real sample. The determination and quantification of benzodiazepines in very small residues of beverages, collected at the scene of drug-facilitated crimes are mandatory in legal procedures. A specific and sensitive analytical instrumentation is needed, involving little or no sample preparation. Here, a direct flow injection analysis of alcoholic beverages spiked with commercially available drugs containing diazepam and flunitrazepam is presented. The method proposed is very fast and requires neither sample preparation nor chromatographic separation. Linearity (R(2) ) was between 0.9977 and 0.9992; LOD and LOQ spanned from 0.01 to 0.02 ng/μL and from 0.1 to 0.5 ng/μL, respectively; intra- and interday repeatabilities were between 1 and 8%. No matrix effects were observed from the comparison of the linear regression curves obtained in real fortified samples and in pure ethanol. Vodka, whisky, and white wine specimens were fortified with commercial drugs, Valium(®) and Rohypnol(®) , at two different concentrations (20 and 50 ng/μL) to simulate the typical amounts found in adulterated real samples and analyzed to demonstrate the method applicability to forensic analyses. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. The study of the varying characteristics of cathodic regions for defective coating in 3.5% sodium chloride solution by EIS and WBE

    NASA Astrophysics Data System (ADS)

    Wang, Haijie; Wang, Jia; Wang, Wei; Zhang, Wei

    2015-04-01

    The current distributions over carbon steel under iron red alkyd primer exposed to 3.5% sodium chloride solution were mapped using the wire beam electrode (WBE). The electrochemical impedance spectroscopy (EIS) of the WBE was carried out to analyze the performance of coating delamination and corrosion behavior of carbon steel beneath defective coating. The EIS data revealed that protective capability of coating decreased with immersion time and the degree of cathodic delamination showed a rapid rise. The current density distribution of WBE indicated that cathodic sites was located at the defect at the beginning of immersion and gradually spread into the intact coating. The cathodic regions were distinguished from the anodic area and distributed over the WBE. The changes of cathodic sites could reflect the deterioration process of defective coating. The cathodic area ratio was a more useful parameter than the cathodic delamination degree to evaluate the coating cathodic delamination. The polarity reversals of electrodes at the defect and beneath coating were observed. A simple discussion of relationship between the blister and the polarity reversal was made from a standpoint of electrochemical distribution. WBE method was able to map and record the changes of local cathodic sites beneath defective coating in real time, which could provide more detailed information about the local degradation of coating.

  19. S4EI (Spectral Sampling with Slicer for Stellar and Extragalactical Instrumentation), a new-generation of 3D spectro-imager dedicated to night astronomy

    NASA Astrophysics Data System (ADS)

    Sayède, Frédéric; Puech, Mathieu; Mein, Pierre; Bonifacio, Piercarlo; Malherbe, Jean-Marie; Galicher, Raphaël.; Amans, Jean-Philippe; Fasola, Gilles

    2014-07-01

    Multichannel Subtractive Double Pass (MSDP) spectrographs have been widely used in solar spectroscopy because of their ability to provide an excellent compromise between field of view and spatial and spectral resolutions. Compared with other types of spectrographs, MSDP can deliver simultaneous monochromatic images at higher spatial and spectral resolutions without any time-scanning requirement (as with Fabry-Perot spectrographs), and with limited loss of flux. These performances are obtained thanks to a double pass through the dispersive element. Recent advances with VPH (Volume phase holographic) Grisms as well as with image slicers now make MSDP potentially sensitive to much smaller fluxes. We present S4EI (Spectral Sampling with Slicer for Stellar and Extragalactical Instrumentation), which is a new concept for extending MSDP to night-time astronomy. It is based on new generation reflecting plane image slicers working with large apertures specific to night-time telescopes. The resulting design could be potentially very attractive and innovative for different domains of astronomy, e.g., the simultaneous spatial mapping of accurately flux-calibrated emission lines between OH sky lines in extragalactic astronomy or the simultaneous imaging of stars, exoplanets and interstellar medium. We present different possible MSDP/S4EI configurations for these science cases and expected performances on telescopes such as the VLT.

  20. Analysis of "total toxaphene" and selected single congeners in biota by ion trap HRGC-EI-MS/MS using congener-optimized parent ion dissociations.

    PubMed

    Skopp, Sonja; Oehme, Michael; Chu, Fong Lam; Yeboah, Faustinus; Chan, Hing Man

    2002-06-15

    A method for the quantification of selected toxaphene congeners as well as "total toxaphene" was developed based on electron ionization (EI) tandem (MS/MS) ion trap mass spectrometry (MS) and a combination of fragment ion dissociations. Congeners were separated by high-resolution gas chromatography. Compared to conventional EI low-resolution MS, a 5-20-fold gain in sensitivity could be obtained for octa- or nonachlorinated compounds such as toxaphene #26 and #62 (according to Parlar nomenclature), allowing for their detection in the low picogram range in biota. In addition, response factors for important congeners such as #26, #32, #40/41, #42, #44, #50, and #62 deviated not more than a factor of 2, which is much less as compared to negative ion chemical ionization. This reduces the risk for systematic errors when determining total toxaphene on the basis of a limited number of reference compounds or the technical mixture. Furthermore, chlordanes and polychlorinated biphenyls did not interfere when applying the proposed MS/MS technique. The applicability of the method was tested by determining both total toxaphene and levels of selected congeners in six Arctic wildlife samples collected from Nunavut, Canada, as well as by repetitive analyses of the SRM 1588 certified reference material.

  1. Constraint on dark matter central density in the Eddington inspired Born-Infeld (EiBI) gravity with input from Weyl gravity

    SciTech Connect

    Potapov, Alexander A.; Mikolaychuk, Olga; Mikolaychuk, Nikolay; Nandi, Kamal K.; Izmailov, Ramil; Ghosh, Mithun E-mail: izmailov.ramil@gmail.com E-mail: mikov94@mail.ru E-mail: kamalnandi1952@yahoo.co.in

    2015-07-01

    Recently, Harko et al. (2014) derived an approximate metric of the galactic halo in the Eddington inspired Born-Infeld (EiBI) gravity. In this metric, we show that there is an upper limit ρ {sub 0}{sup upper} on the central density ρ {sub 0} of dark matter such that stable circular orbits are possible only when the constraint ρ {sub 0}≤ ρ {sub 0}{sup upper} is satisfied in each galactic sample. To quantify different ρ {sub 0}{sup upper} for different samples, we follow the novel approach of Edery and Paranjape (1998), where we use as input the geometric halo radius R{sub WR} from Weyl gravity and equate it with the dark matter radius R{sub DM} from EiBI gravity for the same halo boundary. This input then shows that the known fitted values of ρ {sub 0} obey the constraint ρ {sub 0}≤ ρ {sub 0}{sup upper}∝  (R{sub WR}){sup −2}. Using the mass-to-light ratios giving α , we shall also evaluate ρ {sub 0}{sup lower} ∝  (α −1)M{sub lum}R{sub WR}{sup −3} and the average dark matter density  ( ρ ) {sup lower}. Quantitatively, it turns out that the interval ρ {sub 0}{sup lower} ≤ ρ {sub 0}≤  ρ {sub 0}{sup upper} verifies reasonably well against many dark matter dominated low surface brightness (LSB) galaxies for which values of ρ {sub 0} are independently known. The interval holds also in the case of Milky Way galaxy. Qualitatively, the existence of a stability induced upper limit  ρ {sub 0}{sup upper} is a remarkable prediction of the EiBI theory.

  2. [International collaboration of the E.I. Martsinovsky Institute of Medical Parasitology and Tropical Medicine: assistance for public health in the Republic of Guinea].

    PubMed

    Konstantinov, O K

    2012-01-01

    Within the framework of international collaboration, the E.I. Martsinovsky Institute of Medical Parasitology and Tropical Medicine (IMPTM), I.M. Sechenov First Moscow State Medical University, assisted the Public Health System of the Republic of Guinea in detecting, diagnosing, studying, and preventing tropical infections of viral, bacterial, and parasitic etiologies, and in training national scientific manpower. The work was under way in the Soviet-Guinea Research Microbiology and Virology Laboratory, USSR Ministry of Health, in the Republic of Guinea (now the Pasteur Institute in Guinea (PIG)) in 1978-1991. The circulation of pathogens of a number of tropical infections, the fauna of vectors and carriers of transmissible infections, and their involvement of the circulation of pathogens of these diseases were found in this period. Consultative-and-methodological and medical assistance was given; national higher- and middle-level brainpower trained. It is expedient to restore scientific ties between the IMPTM and the PIG.

  3. The relationship between the surface composition and electrical properties of corrosion films formed on carbon steel in alkaline sour medium: an XPS and EIS study.

    PubMed

    Galicia, Policarpo; Batina, Nikola; González, Ignacio

    2006-07-27

    This work studies the evolution of 1018 carbon steel surfaces during 3-15 day immersion in alkaline sour medium 0.1 M (NH4)2S and 10 ppm CN(-) as (NaCN). During this period of time, surfaces were jointly characterized by electrochemical techniques in situ (electrochemical impedance spectroscopy, EIS) and spectroscopic techniques ex situ (X-ray photoelectron spectroscopy, XPS). The results obtained by these techniques allowed for a description of electrical and chemical properties of the films of corrosion products formed at the 1018 steel surface. There is an interconversion cycle of chemical species that form films of corrosion products whose conversion reactions favor two different types of diffusions inside the films: a chemical diffusion of iron cations and a typical diffusion of atomic hydrogen. These phenomena jointly control the passivity of the interface attacked by the corrosive medium.

  4. AFM, CLSM and EIS characterization of the immobilization of antibodies on indium-tin oxide electrode and their capture of Legionella pneumophila.

    PubMed

    Souiri, Mina; Blel, Nesrine; Sboui, Dejla; Mhamdi, Lotfi; Epalle, Thibaut; Mzoughi, Ridha; Riffard, Serge; Othmane, Ali

    2014-01-01

    The microscopic surface molecular structures and properties of monoclonal anti-Legionella pneumophila antibodies on an indium-tin oxide (ITO) electrode surface were studied to elaborate an electrochemical immunosensor for Legionella pneumophila detection. A monoclonal anti-Legionella pneumophila antibody (MAb) has been immobilized onto an ITO electrode via covalent chemical bonds between antibodies amino-group and the ring of (3-Glycidoxypropyl) trimethoxysilane (GPTMS). The functionalization of the immunosensor was characterized by atomic force microscopy (AFM), water contact angle measurement, cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) in the presence of [Fe(CN)₆](3-/4-) as a redox probe. Specific binding of Legionella pneumophila sgp 1 cells onto the antibody-modified ITO electrode was shown by confocal laser scanning microscopy (CLSM) imaging and EIS. AFM images evidenced the dense and relatively homogeneous morphology on the ITO surface. The formation of the complex epoxysilane-antibodies acting as barriers for the electron transfer between the electrode surface and the redox species in the solution induced a significant increase in the charge transfer resistance (Rct) compared to all the electric elements. A linear relationship between the change in charge transfer resistance (ΔRct=Rct after immunoreactions - Rct control) and the logarithmic concentration value of L. pneumophila was observed in the range of 5 × 10(1)-5 × 10(4) CFU mL(-1) with a limit of detection 5 × 10(1)CFU mL(-1). The present study has demonstrated the successful deposition of an anti-L. pneumophila antibodies on an indium-tin oxide surface, opening its subsequent use as immuno-captor for the specific detection of L. pneumophila in environmental samples. © 2013 Elsevier B.V. All rights reserved.

  5. A novel study of screening and confirmation of modafinil, adrafinil and their metabolite modafinilic acid under EI-GC-MS and ESI-LC-MS-MS ionization

    PubMed Central

    Dubey, S.; Ahi, S.; Reddy, I. M.; Kaur, T.; Beotra, A.; Jain, S.

    2009-01-01

    Objective: Adrafinil and modafinil have received wide publicity and have become controversial in the sporting world when several athletes were discovered allegedly using these drugs as doping agents. By acknowledging the facts, the World Anti-Doping Agency (WADA) banned these drugs in sports since 2004. The present study explores the possibility of differentiating adrafinil and modafinil and their major metabolites under electron impact ionization in gas chromatograph–mass spectrometer (GC-MSD) and electrospray ionization in liquid chromatograph–mass spectrometer (LC-MS/MS) by studying the fragmentation pattern of these drugs. Materials and Methods: Adrafinil, modafinil and their major metabolite, modafinilic acid were analyzed on EI-GC-MSD and ESI-LC-MS/MS using various individual parameters on both the instruments. The analytical technique and equipment used in the analysis were an Agilent 6890N GC with 5973 mass selective detector for the GC-MSD analysis and an Agilent 1100 HPLC with API-3200 Triple quadrupole mass spectrometer for the LC-MS/MS analysis. Validation of both methods was performed using six replicates at different concentrations. Result and Discussion: The results show that adrafinil, modafinil and their major metabolite modafinilic acid could be detected as a single artifact without differentiation under EI-GC-MSD analysis. However, all drugs could be detected and differentiated under ESI-LCMS/MS analysis without any artifaction. The GC-MSD analysis gives a single artifact for both the drugs without differentiation and thus can be used as a marker for screening purposes. Further, the Multiple Reaction Monitoring (MRM) method developed under LC-MS/MS is fit for the purpose for confirmation of suspicious samples in routine sports testing and in forensic and clinical analysis. PMID:20407560

  6. Development and validation of a GC-EI-MS method with reduced adsorption loss for the quantification of olanzapine in human plasma.

    PubMed

    Ikeda, Kayo; Ikawa, Kazuro; Kozumi, Toshihiro; Yokoshige, Satoko; Horikawa, Shunji; Morikawa, Norifumi

    2012-06-01

    A simple and sensitive GC-EI-MS method using solvent extraction and evaporation was developed for the determination of olanzapine concentrations in plasma samples. Because olanzapine and promazine, which was used as the internal standard (IS), are nitrogenous bases, they can adsorb to the weakly acidic silanol groups on the surfaces of glass centrifuge tubes during solvent extraction and evaporation. Silylation of the glass tubes, addition of triethylamine (TEA), and use of a sample solution with a basic pH could prevent adsorption loss. The extraction method involved mixing plasma (500 μL) in a silylated glass tube with a promazine solution (2 μg/mL, 25 μL) in methanol containing 1% TEA. After addition of aqueous sodium carbonate (0.5 mol/L, pH 11.1, 1 mL) and extraction into 3 mL of dichloromethane/n-hexane (1:1, v/v) containing 1% TEA, the organic phase was evaporated to dryness in a silylated glass tube. The residue was dissolved in ethyl acetate containing 1% TEA (50 μL). For GC-EI-MS analysis, the calibration curves of olanzapine in human plasma were linear from 0.5 to 100 ng/mL. Intra- and interday precisions in plasma were both less than 7.36% (coefficient of variation), and the accuracy was between 94.6 and 110% for solutions with concentrations greater than 0.5 ng/mL. The limit of quantification was 0.5 ng/mL in plasma. The assay was applied to therapeutic drug monitoring in samples from three schizophrenic patients.

  7. A novel study of screening and confirmation of modafinil, adrafinil and their metabolite modafinilic acid under EI-GC-MS and ESI-LC-MS-MS ionization.

    PubMed

    Dubey, S; Ahi, S; Reddy, I M; Kaur, T; Beotra, A; Jain, S

    2009-12-01

    Adrafinil and modafinil have received wide publicity and have become controversial in the sporting world when several athletes were discovered allegedly using these drugs as doping agents. By acknowledging the facts, the World Anti-Doping Agency (WADA) banned these drugs in sports since 2004. The present study explores the possibility of differentiating adrafinil and modafinil and their major metabolites under electron impact ionization in gas chromatograph-mass spectrometer (GC-MSD) and electrospray ionization in liquid chromatograph-mass spectrometer (LC-MS/MS) by studying the fragmentation pattern of these drugs. Adrafinil, modafinil and their major metabolite, modafinilic acid were analyzed on EI-GC-MSD and ESI-LC-MS/MS using various individual parameters on both the instruments. The analytical technique and equipment used in the analysis were an Agilent 6890N GC with 5973 mass selective detector for the GC-MSD analysis and an Agilent 1100 HPLC with API-3200 Triple quadrupole mass spectrometer for the LC-MS/MS analysis. Validation of both methods was performed using six replicates at different concentrations. The results show that adrafinil, modafinil and their major metabolite modafinilic acid could be detected as a single artifact without differentiation under EI-GC-MSD analysis. However, all drugs could be detected and differentiated under ESI-LCMS/MS analysis without any artifaction. The GC-MSD analysis gives a single artifact for both the drugs without differentiation and thus can be used as a marker for screening purposes. Further, the Multiple Reaction Monitoring (MRM) method developed under LC-MS/MS is fit for the purpose for confirmation of suspicious samples in routine sports testing and in forensic and clinical analysis.

  8. Study of extreme-ultraviolet emission and properties of a coronal streamer from PROBA2/SWAP, HINODE/EIS and Mauna Loa Mk4 observations

    SciTech Connect

    Goryaev, F.; Slemzin, V.; Vainshtein, L.; Williams, David R.

    2014-02-01

    Wide-field extreme-ultraviolet (EUV) telescopes imaging in spectral bands sensitive to 1 MK plasma on the Sun often observe extended, ray-like coronal structures stretching radially from active regions to distances of 1.5-2 R {sub ☉}, which represent the EUV counterparts of white-light streamers. To explain this phenomenon, we investigated the properties of a streamer observed on 2010 October 20 and 21, by the PROBA2/SWAP EUV telescope together with the Hinode/EIS (HOP 165) and the Mauna Loa Mk4 white-light coronagraph. In the SWAP 174 Å band comprising the Fe IX-Fe XI lines, the streamer was detected to a distance of 2 R {sub ☉}. We assume that the EUV emission is dominated by collisional excitation and resonant scattering of monochromatic radiation coming from the underlying corona. Below 1.2 R {sub ☉}, the plasma density and temperature were derived from the Hinode/EIS data by a line-ratio method. Plasma conditions in the streamer and in the background corona above 1.2 R {sub ☉} from the disk center were determined by forward-modeling the emission that best fit the observational data in both EUV and white light. It was found that the plasma in the streamer above 1.2 R {sub ☉} is nearly isothermal, with a temperature of T = 1.43 ± 0.08 MK. The hydrostatic scale-height temperature determined from the evaluated density distribution was significantly higher (1.72 ± 0.08 MK), which suggests the existence of outward plasma flow along the streamer. We conclude that, inside the streamer, collisional excitation provided more than 90% of the observed EUV emission, whereas, in the background corona, the contribution of resonance scattering became comparable with that of collisions at R ≳ 2 R {sub ☉}.

  9. Correction: Synthesis of 2-deoxy-2,2-difluoro-α-maltosyl fluoride and its X-ray structure in complex with Streptomyces coelicolor GlgEI-V279S.

    PubMed

    Thanna, Sandeep; Lindenberger, Jared J; Gaitonde, Vishwanath V; Ronning, Donald R; Sucheck, Steven J

    2015-08-07

    Correction for 'Synthesis of 2-deoxy-2,2-difluoro-α-maltosyl fluoride and its X-ray structure in complex with Streptomyces coelicolor GlgEI-V279S' by Sandeep Thanna et al., Org. Biomol. Chem., 2015, DOI: 10.1039/c5ob00867k.

  10. Two structurally different dienelactone hydrolases (TfdEI and TfdEII) from Cupriavidus necator JMP134 plasmid pJP4 catalyse cis- and trans-dienelactones with similar efficiency.

    PubMed

    Kumar, Ajit; Pillay, Balakrishna; Olaniran, Ademola O

    2014-01-01

    In this study, dienelactone hydrolases (TfdEI and TfdEII) located on plasmid pJP4 of Cupriavidus necator JMP134 were cloned, purified, characterized and three dimensional structures were predicted. tfdEI and tfdEII genes were cloned into pET21b vector and expressed in E. coli BL21(DE3). The enzymes were purified by applying ultra-membrane filtration, anion-exchange QFF and gel-filtration columns. The enzyme activity was determined by using cis-dienelactone. The three-dimensional structure of enzymes was predicted using SWISS-MODEL workspace and the biophysical properties were determined on ExPASy server. Both TfdEI and TfdEII (Mr 25 kDa) exhibited optimum activity at 37°C and pH 7.0. The enzymes retained approximately 50% of their activity after 1 h of incubation at 50°C and showed high stability against denaturing agents. The TfdEI and TfdEII hydrolysed cis-dienelactone at a rate of 0.258 and 0.182 µMs(-1), with a Km value of 87 µM and 305 µM, respectively. Also, TfdEI and TfdEII hydrolysed trans-dienelactone at a rate of 0.053 µMs(-1) and 0.0766 µMs(-1), with a Km value of 84 µM and 178 µM, respectively. The TfdEI and TfdEII kcat/Km ratios were 0.12 µM(-1) s(-1) and 0.13 µM(-1) s(-1) and 0.216 µM(-1) s(-1) and 0.094 µM(-1) s(-1) for for cis- and trans-dienelactone, respectively. The kcat/Km ratios for cis-dienelactone show that both enzymes catalyse the reaction with same efficiency even though Km value differs significantly. This is the first report to characterize and compare reaction kinetics of purified TfdEI and TfdEII from Cupriavidus necator JMP134 and may be helpful for further exploration of their catalytic mechanisms.

  11. Two Structurally Different Dienelactone Hydrolases (TfdEI and TfdEII) from Cupriavidus necator JMP134 Plasmid pJP4 Catalyse Cis- and Trans-Dienelactones with Similar Efficiency

    PubMed Central

    Kumar, Ajit; Pillay, Balakrishna; Olaniran, Ademola O.

    2014-01-01

    In this study, dienelactone hydrolases (TfdEI and TfdEII) located on plasmid pJP4 of Cupriavidus necator JMP134 were cloned, purified, characterized and three dimensional structures were predicted. tfdEI and tfdEII genes were cloned into pET21b vector and expressed in E. coli BL21(DE3). The enzymes were purified by applying ultra-membrane filtration, anion-exchange QFF and gel-filtration columns. The enzyme activity was determined by using cis-dienelactone. The three-dimensional structure of enzymes was predicted using SWISS-MODEL workspace and the biophysical properties were determined on ExPASy server. Both TfdEI and TfdEII (Mr 25 kDa) exhibited optimum activity at 37°C and pH 7.0. The enzymes retained approximately 50% of their activity after 1 h of incubation at 50°C and showed high stability against denaturing agents. The TfdEI and TfdEII hydrolysed cis-dienelactone at a rate of 0.258 and 0.182 µMs−1, with a Km value of 87 µM and 305 µM, respectively. Also, TfdEI and TfdEII hydrolysed trans-dienelactone at a rate of 0.053 µMs−1 and 0.0766 µMs−1, with a Km value of 84 µM and 178 µM, respectively. The TfdEI and TfdEII kcat/Km ratios were 0.12 µM−1s−1and 0.13 µM−1s−1 and 0.216 µM−1s−1 and 0.094 µM−1s−1 for for cis- and trans-dienelactone, respectively. The kcat/Km ratios for cis-dienelactone show that both enzymes catalyse the reaction with same efficiency even though Km value differs significantly. This is the first report to characterize and compare reaction kinetics of purified TfdEI and TfdEII from Cupriavidus necator JMP134 and may be helpful for further exploration of their catalytic mechanisms. PMID:25054964

  12. Materials-Enabled High-Efficiency (MEHE) Heavy-Duty Diesel Engines

    SciTech Connect

    Kass, M.; Veliz, M.

    2011-09-30

    The purpose of this Cooperative Research and Development Agreement (CRADA) between UTBattelle, Inc. and Caterpillar, Inc. was to improve diesel engine efficiency by incorporating advanced materials to enable higher combustion pressures and temperatures necessary for improved combustion. The project scope also included novel materials for use in advanced components and designs associated with waste-heat recovery and other concepts for improved thermal efficiency. Caterpillar initially provided ORNL with a 2004 Tier 2 C15 ACERT diesel engine (designed for on-highway use) and two 600 hp motoring dynamometers. The first year of the CRADA effort was focused on establishing a heavy-duty experimental engine research cell. First year activities included procuring, installing and commissioning the cell infrastructure. Infrastructure components consisted of intake air handling system, water tower, exhaust handling system, and cell air conditioning. Other necessary infrastructure items included the fuel delivery system and bottled gas handling to support the analytical instrumentation. The second year of the CRADA focused on commissioning the dynamometer system to enable engine experimentation. In addition to the requirements associated with the dynamometer controller, the electrical system needed a power factor correction system to maintain continuity with the electrical grid. During the second year the engine was instrumented and baseline operated to confirm performance and commission the dynamometer. The engine performance was mapped and modeled according to requirements provided by Caterpillar. This activity was further supported by a Work-for-Others project from Caterpillar to evaluate a proprietary modeling system. A second Work-for-Others activity was performed to evaluate a novel turbocharger design. This project was highly successful and may lead to new turbocharger designs for Caterpillar heavy-duty diesel engines. During the third (and final) year of the CRADA, a novel valve material was evaluated to assess high temperature performance and durability. A series of prototype valves, composed of a unique nickel-alloy was placed in the engine head. The engine was aggressively operated using a transient test cycle for 200 hours. The valve recession was periodically measured to determine valve performance. Upon completion of the test the valves were removed and returned to Caterpillar for additional assessment. Industrial in-kind support was available throughout the project period. Review of the status and research results were carried out on a regular basis (meetings and telecons) which included direction for future work activities. A significant portion of the industrial support was in the form of information exchange and technical consultation.

  13. The Europa Imaging System (EIS): High-Resolution, 3-D Insight into Europa's Geology, Ice Shell, and Potential for Current Activity

    NASA Astrophysics Data System (ADS)

    Turtle, E. P.; McEwen, A. S.; Collins, G. C.; Fletcher, L. N.; Hansen, C. J.; Hayes, A.; Hurford, T., Jr.; Kirk, R. L.; Barr, A.; Nimmo, F.; Patterson, G.; Quick, L. C.; Soderblom, J. M.; Thomas, N.

    2015-12-01

    The Europa Imaging System will transform our understanding of Europa through global decameter-scale coverage, three-dimensional maps, and unprecedented meter-scale imaging. EIS combines narrow-angle and wide-angle cameras (NAC and WAC) designed to address high-priority Europa science and reconnaissance goals. It will: (A) Characterize the ice shell by constraining its thickness and correlating surface features with subsurface structures detected by ice penetrating radar; (B) Constrain formation processes of surface features and the potential for current activity by characterizing endogenic structures, surface units, global cross-cutting relationships, and relationships to Europa's subsurface structure, and by searching for evidence of recent activity, including potential plumes; and (C) Characterize scientifically compelling landing sites and hazards by determining the nature of the surface at scales relevant to a potential lander. The NAC provides very high-resolution, stereo reconnaissance, generating 2-km-wide swaths at 0.5-m pixel scale from 50-km altitude, and uses a gimbal to enable independent targeting. NAC observations also include: near-global (>95%) mapping of Europa at ≤50-m pixel scale (to date, only ~14% of Europa has been imaged at ≤500 m/pixel, with best pixel scale 6 m); regional and high-resolution stereo imaging at <1-m/pixel; and high-phase-angle observations for plume searches. The WAC is designed to acquire pushbroom stereo swaths along flyby ground-tracks, generating digital topographic models with 32-m spatial scale and 4-m vertical precision from 50-km altitude. These data support characterization of cross-track clutter for radar sounding. The WAC also performs pushbroom color imaging with 6 broadband filters (350-1050 nm) to map surface units and correlations with geologic features and topography. EIS will provide comprehensive data sets essential to fulfilling the goal of exploring Europa to investigate its habitability and perform

  14. The Europa Imaging System (EIS): High-Resolution, 3-D Insight into Europa's Geology, Ice Shell, and Potential for Current Activity

    NASA Astrophysics Data System (ADS)

    Turtle, E. P.; McEwen, A. S.; Collins, G. C.; Fletcher, L. N.; Hansen, C. J.; Hayes, A.; Hurford, T., Jr.; Kirk, R. L.; Barr, A.; Nimmo, F.; Patterson, G.; Quick, L. C.; Soderblom, J. M.; Thomas, N.

    2014-12-01

    The Europa Imaging System will transform our understanding of Europa through global decameter-scale coverage, three-dimensional maps, and unprecedented meter-scale imaging. EIS combines narrow-angle and wide-angle cameras (NAC and WAC) designed to address high-priority Europa science and reconnaissance goals. It will: (A) Characterize the ice shell by constraining its thickness and correlating surface features with subsurface structures detected by ice penetrating radar; (B) Constrain formation processes of surface features and the potential for current activity by characterizing endogenic structures, surface units, global cross-cutting relationships, and relationships to Europa's subsurface structure, and by searching for evidence of recent activity, including potential plumes; and (C) Characterize scientifically compelling landing sites and hazards by determining the nature of the surface at scales relevant to a potential lander. The NAC provides very high-resolution, stereo reconnaissance, generating 2-km-wide swaths at 0.5-m pixel scale from 50-km altitude, and uses a gimbal to enable independent targeting. NAC observations also include: near-global (>95%) mapping of Europa at ≤50-m pixel scale (to date, only ~14% of Europa has been imaged at ≤500 m/pixel, with best pixel scale 6 m); regional and high-resolution stereo imaging at <1-m/pixel; and high-phase-angle observations for plume searches. The WAC is designed to acquire pushbroom stereo swaths along flyby ground-tracks, generating digital topographic models with 32-m spatial scale and 4-m vertical precision from 50-km altitude. These data support characterization of cross-track clutter for radar sounding. The WAC also performs pushbroom color imaging with 6 broadband filters (350-1050 nm) to map surface units and correlations with geologic features and topography. EIS will provide comprehensive data sets essential to fulfilling the goal of exploring Europa to investigate its habitability and perform

  15. CON4EI: EpiOcular™ Eye Irritation Test (EpiOcular™ EIT) for hazard identification and labelling of eye irritating chemicals.

    PubMed

    Kandarova, H; Letasiova, S; Adriaens, E; Guest, R; Willoughby, J A; Drzewiecka, A; Gruszka, K; Alépée, Nathalie; Verstraelen, Sandra; Van Rompay, An R

    2017-07-08

    Assessment of the acute eye irritation potential is part of the international regulatory requirements for testing of chemicals. The objective of the CON4EI project was to develop tiered testing strategies for eye irritation assessment. A set of 80 reference chemicals (38 liquids and 42 solids) was tested with eight different methods. Here, the results obtained with the EpiOcular™ Eye Irritation Test (EIT), adopted as OECD TG 492, are shown. The primary aim of this study was to evaluate of the performance of the test method to discriminate between chemicals not requiring classification for serious eye damage/eye irritancy (No Category) and chemicals requiring classification and labelling. In addition, the predictive capacity in terms of in vivo drivers of classification (i.e. corneal opacity, conjunctival redness and persistence at day 21) was investigated. EpiOcular™ EIT achieved a sensitivity of 97%, a specificity of 87% and accuracy of 95% and also confirmed its excellent reproducibility (100%) from the original validation. The assay was applicable to all chemical categories tested in this project and its performance was not limited to the particular driver of the classification. In addition to the existing prediction model for dichotomous categorization, a new prediction model for Cat 1 is suggested. Copyright © 2017. Published by Elsevier Ltd.

  16. CON4EI: Slug Mucosal Irritation (SMI) test method for hazard identification and labelling of serious eye damaging and eye irritating chemicals.

    PubMed

    Adriaens, E; Guest, R; Willoughby, J A; Fochtman, P; Kandarova, H; Verstraelen, S; Van Rompay, A R

    2017-09-01

    Assessment of ocular irritancy is an international regulatory requirement in the safety evaluation of industrial and consumer products. Although many in vitro ocular irritation assays exist, alone they are incapable of fully categorizing chemicals. The objective of CEFIC-LRI-AIMT6-VITO CON4EI (CONsortium for in vitro Eye Irritation testing strategy) project was to develop tiered testing strategies for eye irritation assessment that can lead to complete replacement of the in vivo Draize rabbit eye test (OECD TG 405). A set of 80 reference chemicals was tested with seven test methods, one method was the Slug Mucosal Irritation (SMI) test method. The method measures the amount of mucus produced (MP) during a single 1-hour contact with a 1% and 10% dilution of the chemical. Based on the total MP, a classification (Cat 1, Cat 2, or No Cat) is predicted. The SMI test method correctly identified 65.8% of the Cat 1 chemicals with a specificity of 90.5% (low over-prediction rate for in vivo Cat 2 and No Cat chemicals). Mispredictions were predominantly unidirectional towards lower classifications with 26.7% of the liquids and 40% of the solids being underpredicted. In general, the performance was better for liquids than for solids with respectively 76.5% vs 57.1% (Cat 1), 61.5% vs 50% (Cat 2), and 87.5% vs 85.7% (No Cat) being identified correctly. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Inactivation of arginine esterase E-I of Bitis gabonica venom by irreversible inhibitors including a water-soluble carbodiimide, a chloromethyl ketone and isatoic anhydride.

    PubMed

    Gravett, P S; Viljoen, C C; Oosthuizen, M M

    1991-01-01

    1. Esterase E-I from Bitis gabonica was inactivated with irreversible inhibitors which included studies with a water-soluble carbodiimide, an affinity labelling peptide and a mechanism-based inactivator. 2. The reaction with 1-ethyl-3(3-dimethylaminopropyl)-carbodiimide was biphasic and the dominant part followed saturation kinetics. At pH 5.5 a rate constant of 0.4 min-1 for inactive enzyme formation was calculated and a dissociation constant (Ki) of 0.2 M for the enzyme-inhibitor complex. 3. Inactivation with D-Phe-Pro-Arg-chloromethyl ketone indicated a two-step mechanism, for which the reaction parameters at pH 8.0 were determined. The Ki value was 0.2 microM and the inactivation rate was 2.5 min-1. 4. With isatoic anhydride pseudo-first-order kinetics was observed. At pH 8.0 a rate constant of 0.9 min-1 and a Ki of 2.0 mM were obtained. The inactivation of the enzyme was found to be governed by a group in the enzyme showing a pK value of 7.3.

  18. Comparison between observed and theoretical O IV line ratios in the UV/EUV solar spectrum as derived by SUMER, CDS and EIS

    NASA Astrophysics Data System (ADS)

    Giunta, A. S.; Fludra, A.; O'Mullane, M. G.; Summers, H. P.

    2012-02-01

    Aims: The joint use of SoHO Solar Ultraviolet Measurement of Emitted Radiation (SUMER), Coronal Diagnostic Spectrometer (CDS) and Hinode Extreme-ultraviolet Imaging Spectrometer (EIS) allow observation of several O iv line ratios, useful for temperature plasma diagnostics. Accurate atomic data are required to avoid interpretation errors in deriving the electron temperature from these ratios. Muglach et al. (2010) found that the measured ratio I(787.72 Å)/I(279.93 Å) is lower than the predicted value by a factor 2-5. Here the predicted value for this ratio is revised using updated atomic data. A comparison with other observed O iv line ratios is shown and the electron temperature is derived. Methods: The analysis is based on new observations made during the observational campaign of April 2009 and including three O iv multiplets. The theoretical ratios have been derived using the Atomic Data and Analysis Structure (ADAS) database and include comparison with the most recent calculations available in the literature. Results: The discrepancy for the O iv I(787.72 Å)/I(279.93 Å) ratio has been solved by adding transitions involving higher excited levels, which have been omitted in previous atomic models. This results in a decrease of the theoretical line ratio, providing electron temperatures in the range of log T = 5.17-5.39, close to the temperature expected from a plasma in ionisation equilibrium.

  19. Poly(3-methylthiophene)/palladium sub-micro-modified sensor electrode. Part II: Voltammetric and EIS studies, and analysis of catecholamine neurotransmitters, ascorbic acid and acetaminophen.

    PubMed

    Atta, Nada F; El-Kady, Maher F

    2009-08-15

    Promising voltammetric sensors based on the modification of Pt and poly(3-methylthiophene) (PMT) electrodes with Pd nanoparticles were achieved for the determination of catecholamine neurotransmitters, ascorbic acid and acetaminophen. Electrochemistry of the indicated compounds was studied at these electrodes and interesting electrocatalytic effects were found. Furthermore, simple, easily prepared one electrochemical step Pd-modified Pt electrode (Pt/Pd) is reported for the first time. Cyclic voltammetry (CV) and chronocoulometry (CC) were used for the determination of the apparent diffusion coefficients in different electrolytes at these electrodes and the values are in the range from 10(-4) to 10(-5)cm(2)s(-1). Furthermore, it was found that the method of polymer formation had a substantial effect on the synergism between the polymer film and the loaded metal particles towards the oxidation of dopamine (DA) in different supporting electrolytes. This was confirmed by the CV, CC and EIS (electrochemical impedance spectroscopy) as well as SEM (Scanning Electron Microscopy) results. Pt and PMT electrodes modified with Pd nanoparticles showed excellent results for the simultaneous determination of tertiary and quaternary mixtures of the studied compounds.

  20. In vitro corrosion study by EIS of an equiatomic NiTi alloy and an implant quality AISI 316 stainless steel.

    PubMed

    Rondelli, G; Torricelli, P; Fini, M; Rimondini, L; Giardino, R

    2006-11-01

    The electrochemical impedance spectroscopy (EIS) technique was used for the study of the electrochemical behavior of an equiatomic NiTi alloy and an implant quality AISI 316 stainless steel type ASTM F138. Experiments were carried out using four different different test solutions: phosphate buffered saline (PBS), Dulbecco minimum essential medium (MEM), MEM + fetal calf serum (FCS), and MEM + fetal calf serum + fibroblast cell (CELL). Specimens were finished to 600-grit SiC paper and were tested in conditions that did not provoke abrupt mechanical damage of the passive film. Bode-phase spectra showed the presence of two maxima and were fitted with an equivalent circuit characterized by two parallel combinations (R, resistance; CPE, constant phase element). The R(1) and CPE(1) branch was assigned to the inner compact passive film and the R(2) and CPE(2) branch to the external porous film. The resistance of the inner film R(1), roughly corresponding to the polarization resistance (R(p)), which is inversely proportional to the material's corrosion rate, increased with the immersion time and was generally greater in PBS than in other media. With the exception of FCS solution, R(1) for NiTi alloy is better or similar to that of ASTM F138.

  1. Upper limit on the central density of dark matter in the Eddington-inspired Born-Infeld (EiBI) gravity

    NASA Astrophysics Data System (ADS)

    Izmailov, Ramil; Potapov, Alexander A.; Filippov, Alexander I.; Ghosh, Mithun; Nandi, Kamal K.

    2015-04-01

    We investigate the stability of circular material orbits in the analytic galactic metric recently derived by Harko et al., Mod. Phys. Lett. A29, 1450049 (2014). It turns out that stability depends more strongly on the dark matter central density ρ0 than on other parameters of the solution. This property then yields an upper limit on ρ0 for each individual galaxy, which we call here ρ 0 upper, such that stable circular orbits are possible only when the constraint ρ 0<= ρ 0 upper is satisfied. This is our new result. To approximately quantify the upper limit, we consider as a familiar example our Milky Way galaxy that has a projected dark matter radius RDM 180 kpc and find that ρ 0 upper ˜ 2.37× 1011 M⊙ kpc-3. This limit turns out to be about four orders of magnitude larger than the latest data on central density ρ0 arising from the fit to the Navarro-Frenk-White (NFW) and Burkert density profiles. Such consistency indicates that the Eddington-inspired Born-Infeld (EiBI) solution could qualify as yet another viable alternative model for dark matter.

  2. Phentermine interference and high L-methamphetamine concentration problems in GC-EI-MS SIM Analyses of R-(-)-α-methoxy-α-(trifluoromethyl)phenylacetyl chloride-derivatized amphetamines and methamphetamines†.

    PubMed

    Hamilton, Theron J; Qui, Harry Z; Dozier, Katherine V R; Fuller, Zachary J

    2014-09-01

    In order to achieve chromatographic separation, urine samples shown to be initially positive for amphetamines and methamphetamines in US Department of Defense immunoassays are derivatized with R-(-)-α-methoxy-α-(trifluoromethyl)phenylacetyl chloride (R-(-)-MTPA) prior to gas chromatography-electron impact-mass spectrometry (GC-EI-MS) analysis. Phentermine, a member of the phenethylamine class of drugs and a common appetite suppressant, interferes with GC-EI-MS assays of R-(-)-MTPA-derivatized d-amphetamine, degrading the chromatography of the internal standard and analyte ions and skewing concentration calculations. Additionally, when specimens with high concentrations of l-methamphetamine are derivatized with R-(-)-MTPA, signal peaks have the potential to be misidentified by integration software as d-methamphetamine. We have found that replacing R-(-) MTPA with (S)-(+)-α-methoxy-α-(trifluoromethyl)phenylacetyl chloride reduces phentermine interference problems related to internal standard chromatography, reduces the possibility of concentrated l-methamphetamine peaks being misidentified by integration software, improves resolution of d-methamphetamine in the presence of high l-methamphetamine concentrations, and is a cost-neutral change that can be applied to current amphetamines GC-EI-MS methods without the need for method modification.

  3. Toxaphene analysis in Great Lakes fish: a comparison of GC-EI/MS/MS and GC-ECNI-MS, individual congener standard and technical mixture for quantification of toxaphene.

    PubMed

    Xia, Xiaoyan; Crimmins, Bernard S; Hopke, Philip K; Pagano, James J; Milligan, Michael S; Holsen, Thomas M

    2009-09-01

    Toxaphene is considered to be a problematic organochlorine pollutant because of its bioaccumulation potential and persistence in aquatic environments. In this study, whole lake trout and walleye composites were used to evaluate two analytical techniques for total toxaphene and selected congener analysis. The efficacy of using gas chromatography electron ionization tandem mass spectrometry (GC-EI/MS/MS) and electron capture negative ionization mass spectrometry (GC-ECNI-MS) were compared. Although the sensitivity using GC-ECNI-MS was approximately five times greater than GC-EI/MS/MS, the latter provided more consistent inter-Parlar relative response factors (RRF). When using technical calibration mixtures, these results suggest a more accurate total toxaphene measurement was obtained using the GC-EI/MS/MS method. Total toxaphene concentrations in lake trout composites from both methods were highly correlated (R(2) = 0.985) with the MS/MS concentrations approximately half of those determined by ECNI, suggesting systematic high bias in toxaphene concentrations when measured using GC-ECNI.

  4. Environmental change and human occupation in the floodplain area of Balta Ialomiţei. The case study of Bordusani Popinǎ Chalcolithic tell settlement

    NASA Astrophysics Data System (ADS)

    Haita, Constantin; Nicolae Popovici, Dragomir; Panaiotu, Cristian

    2016-04-01

    The floodplain area of Balta Ialomiței, between Cǎl\\varasi and Giurgeni, delimited by Borcea River and Danube is formed by an anostomosing system, up to 13 km wide and 70 km long; this zone has a particular important evolution in Holocene for the alluvial system and associated environment. The Chalcolithic occupation in southern and eastern Romania is marked by the development of tell type settlements along the Danube and its main tributaries, chronologically attributed to Gumelnița culture, Vth millenium BC, one of the most important civilisation in the Lower Danube zone. In this area, the most representative settlements are: Borduşani Popinǎ, Hârşova tell and Popina Blagodeasca, situated either on erosional remnants from terraces ("popine") or on the edge of the lower terrace. Bordusani Popinǎ is located inside the floodplain zone, on a remnant separated from the lower terrace of Borcea River, in Romanian Plain. On this site, a pluridisciplinary research program allowed the investigation of Chalcolithic occupation in terms of archaeological, geomorphological, archaeozoological, archaeobotanical and petrographical point of view. The Chalcolithic occupation is represented by successive levels of dwellings, destroyed by fire and also unburned; their stratigraphic relationships, together with the presence of passageways and domestic waste areas, revealed an organised internal space. In Balta Ialomiței meadow area, a paleoenvironmental research was iniatiated with a Cobra TT percussion corer in five important locations, on a West-East alignament. The bulk samples were investigated for grainsize, clay mineralogy and magnetic susceptibility. This study was completed with the micromorphology analysis on undisturbed samples of the sedimentary succession from a tubed core located in the eastern vecinity of the tell. Our results show important environmental changes in the period from Chalcolithic to Iron Age and Middle Ages. The analysed sequence, from the

  5. CON4EI: Development of serious eye damage and eye irritation testing strategies with respect to the requirements of the UN GHS/EU CLP hazard categories.

    PubMed

    Verstraelen, Sandra; Van Rompay, An R

    2017-06-16

    The main objective of the CON4EI (CONsortium for in vitro Eye Irritation testing strategy) project (2015-2016) was to develop tiered, non-animal testing strategies for serious eye damage and eye irritation assessment in relation to the most important drivers of classification. The serious eye damage and eye irritation potential of a set of 80 chemicals was identified based on existing in vivo Draize eye test data and testing was conducted using the following eight alternative test methods: BCOP (Bovine Corneal Opacity and Permeability)+histopathology, BCOP-LLBO (BCOP Laser Light-Based Opacitometer), ICE (Isolated Chicken Eye)+histopathology, STE (Short Term Exposure), EpiOcular™ EIT (EpiOcular Eye Irritation Test), EpiOcular™ ET-50 (EpiOcular™ Time-to-toxicity), SkinEthic™ HCE EIT (SkinEthic™ Human Corneal Epithelial Eye Irritation Test), and SMI (Slug Mucosal Irritation). Project management decided to not include the ICE data in this project since the execution showed relevant, and not predictable, deviations from Organisation for Economic Co-operation and Development (OECD) Test Guideline (TG) 438 and Guidance Document 160. At this stage, the outcome of these deviations has not been fully assessed. In addition to these alternative test methods, the computational models Toxtree and Case Ultra were taken into account. This project assessed the relevance of these test methods, their applicability domains and limitations in terms of 'drivers of classification', and their strengths and weaknesses. In this way, methods were identified that fit into a tiered-testing strategy for serious eye damage/eye irritation assessment to distinguish United Nations Globally Harmonized System of Classification and Labelling of Chemicals (UN GHS) Category 1 (Cat 1) chemicals from non-Cat 1 chemicals and address the gap namely distinguish between Category 2 (Cat 2) and Cat 1 chemicals. Copyright © 2017. Published by Elsevier Ltd.

  6. CON4EI: Development of testing strategies for hazard identification and labelling for serious eye damage and eye irritation of chemicals.

    PubMed

    Adriaens, E; Verstraelen, S; Alépée, N; Kandarova, H; Drzewiecka, A; Gruszka, K; Guest, R; Willoughby, J A; Van Rompay, A R

    2017-09-27

    Assessment of acute eye irritation potential is part of the international regulatory requirements for safety testing of chemicals. In the last decades, many efforts have been made in the search for alternative methods to replace the regulatory in vivo Draize rabbit eye test (OECD TG 405). Success in terms of complete replacement of the regulatory in vivo Draize rabbit eye test has not yet been achieved. The main objective of the CEFIC-LRI-AIMT6-VITO CON4EI (CONsortium for in vitro Eye Irritation testing strategy) project was to develop tiered testing strategies for serious eye damage and eye irritation assessment that can lead to complete replacement of OECD TG 405. A set of 80 reference chemicals (e.g. balanced by important driver of classification and physical state), was tested with seven test methods. Based on the results of this project, three different strategies were suggested. We have provided a standalone (EpiOcular ET-50), a two-tiered and three-tiered strategy, that can be used to distinguish between Cat 1 and Cat 2 chemicals and chemicals that do not require classification (No Cat). The two-tiered and three-tiered strategies use an RhCE test method (EpiOcular EIT or SkinEthic™ EIT) at the bottom (identification No Cat) in combination with the BCOP LLBO (two-tiered strategy) or BCOP OP-KIT and SMI (three-tiered strategy) at the top (identification Cat 1). For our proposed strategies, 71.1% - 82.9% Cat 1, 64.2% - 68.5% Cat 2 and ≥80% No Cat chemicals were correctly identified. Also, similar results were obtained for the Top-Down and Bottom-Up approach. Copyright © 2017. Published by Elsevier Ltd.

  7. CON4EI: SkinEthic™ Human Corneal Epithelium Eye Irritation Test (SkinEthic™ HCE EIT) for hazard identification and labelling of eye irritating chemicals.

    PubMed

    Van Rompay, A R; Alépée, N; Nardelli, L; Hollanders, K; Leblanc, V; Drzewiecka, A; Gruszka, K; Guest, R; Kandarova, H; Willoughby, J A; Verstraelen, S; Adriaens, E

    2017-06-15

    Assessment of ocular irritancy is an international regulatory requirement and a necessary step in the safety evaluation of industrial and consumer products. Although a number of in vitro ocular irritation assays exist, none are capable of fully categorizing chemicals as a stand-alone assay. Therefore, the CEFIC-LRI-AIMT6-VITO CON4EI (CONsortium for in vitro Eye Irritation testing strategy) project was developed with the goal of assessing the reliability of eight in vitro/alternative test methods as well as establishing an optimal tiered-testing strategy. One of the in vitro assays selected was the validated SkinEthic™ Human Corneal Epithelium Eye Irritation Test method (SkinEthic™ HCE EIT). The SkinEthic™ HCE EIT has already demonstrated its capacity to correctly identify chemicals (both substances and mixtures) not requiring classification and labelling for eye irritation or serious eye damage (No Category). The goal of this study was to evaluate the performance of the SkinEthic™ HCE EIT test method in terms of the important in vivo drivers of classification. For the performance with respect to the drivers all in vivo Cat 1 and No Cat chemicals were 100% correctly identified. For Cat 2 chemicals the liquids and the solids had a sensitivity of 100% and 85.7%, respectively. For the SkinEthic™ HCE EIT test method, 100% concordance in predictions (No Cat versus No prediction can be made) between the two participating laboratories was obtained. The accuracy of the SkinEthic™ HCE EIT was 97.5% with 100% sensitivity and 96.9% specificity. The SkinEthic™ HCE EIT confirms its excellent results of the validation studies. Copyright © 2017. Published by Elsevier Ltd.

  8. Supplement Analysis for the Transmission System Vegetation Management Program FEIS (DOE/EIS-0285/SA-151-Big Eddy-Ostrander 1)

    SciTech Connect

    Stratton, Elaine

    2003-05-08

    Removal of danger trees along the Big Eddy-Ostrander-1 transmission line corridor. This corridor also includes segments of the Big Eddy-Troutdale, Ostrander-Troutdale, Big Eddy-McLoughlin and Bid Eddy-Chemawa transmission lines. Referencing the Big-Eddy-Ostrander-1 transmission line, the project extends from tower 39/3 to 72/2. The portion of the ROW extending from 39/3 west to 44/5+313 falls within the Zigzag Ranger District of the Mt. Hood National Forest, Clackamas County, Oregon. All work conducted within the Mt. Hood National Forest has been previously addressed in the Supplement Analysis for the Transmission System Vegetation Management Program (DOE/EIS-0285/SA-113-1) dated 12/02/2002 and will conform to the requirements therein. This Supplement Analysis evaluates that portion of the project proposed for the remainder of the transmission line corridor extending from 44/5+313 west to 72/2. BPA proposes to manually remove danger trees located along the indicated transmission line rights-of-ways that are approaching electrical clearance zones defined in accordance with the National Electrical Safety Code and BPA Standards. Manual removal involves chainsaws, brush cutters, or hand tools. BPA would then treat the associated hardwood stumps with herbicides using spot and localized treatments to ensure that the roots are killed and to prevent new sprouts. Spot treatments and localized treatments consist of direct applications of herbicide to an individual target plant or small group of plants using minimal amounts of herbicide. See Section 1.1 of the attached checklist for pertinent information on each section of referenced transmission line included in the proposal.

  9. Cyclic acyloxonium ions as diagnostic aids in the characterization of chloropropanol esters under electron impact (EI), electrospray ionization (ESI), and atmospheric pressure chemical ionization (APCI) conditions.

    PubMed

    Rahn, Anja K K; Yaylayan, Varoujan A

    2013-06-26

    During mass spectrometric analysis of various lipids and lipid derivatives such as the chlorinated counterparts of triacylglycerols, the detailed structure of the characteristic and common ions formed under electron impact (EI), electrospray ionization (ESI), and atmospheric pressure chemical ionization (APCI) conditions by the loss of a single fatty acid remains ambiguous. These ions are designated in the literature as "diacylglyceride ions" and are frequently depicted with a molecular formula without showing any structural features and sometimes represented as cyclic acyloxonium ions. Characterization of these ions is of considerable importance due to their utility in structural identification of lipid derivatives. This study provides complementary evidence on the cyclic nature of "diacylglyceride ions" through the use of the simplest 3-monochloropropanediol diester as a model and the use of isotope labeling technique. Tandem MS/MS studies have indicated that the ion at m/z 135.6 generated from 1,2-bis(acetoyl)-3-chloropropane through the loss of an acetyl group was identical to the ion at m/z 135.6 generated from 4-chloromethyl-2,2-dimethyl-1,3-dioxolane, the latter being generated from a cyclic precursor through the loss of a methyl radical, keeping the dioxolane ring structure intact, thus confirming the cyclic nature of these ions. The corresponding cyclic oxonium ions generated from longer chain chloropropanol diesters, such as the ion at m/z 331.2 originating from 3-monochloropropanediol (3-MCPD) diesters containing palmitic acid(s), could serve as chemical markers for the presence chloropropanol esters.

  10. Bis(9)-(-)-nor-meptazinol as a novel dual-binding AChEI potently ameliorates scopolamine-induced cognitive deficits in mice.

    PubMed

    Liu, Ting; Xia, Zheng; Zhang, Wei-Wei; Xu, Jian-rong; Ge, Xin-Xing; Li, Juan; Cui, Yongyao; Qiu, Zhui-Bai; Xu, Jun; Xie, Qiong; Wang, Hao; Chen, Hong-Zhuan

    2013-03-01

    Alzheimer's disease (AD) is a multifaceted neurodegenerative disorder which is characterized by the progressive deterioration of cognition and the emergence of behavioral and psychological symptoms in aging patients. Given that the clinical effectiveness of acetylcholinesterase inhibitors (AChEIs) has still been questioned due to dubious disease-modifying effects, the multi-target directed ligand (MTDL) design has become an emerging strategy for developing new drugs for AD treatment. Bis(9)-(-)-nor-meptazinol (Bis-Mep) was firstly reported by us as a novel MTDL for both potent cholinesterase and amyloid-β aggregation inhibition. In this study, we further explored its AChE inhibition kinetic features and cognitive amelioration. Bis-Mep was found to be a mixed-type inhibitor on electric eel AChE by enzyme kinetic study. Molecular docking revealed that two "water bridges" located at the two wings of Bis-Mep stabilized its interaction with both catalytic and peripheral anionic sites of AChE. Furthermore, subcutaneous administration of Bis-Mep (10, 100 or 1000 ng/kg) significantly reversed the scopolamine-induced memory deficits in a typical bell-shaped dose-response manner. The maximal cognitive amelioration of Bis-Mep was achieved at 100 ng/kg, comparable with the effect of a reference drug Huperzine A at 1 mg/kg and also the relevant AChE inhibition in brain. These findings suggested that Bis-Mep might be a promising dual-binding AChE inhibitor for potential AD therapeutics.

  11. Zirconium immobilized on gold-mercaptopropionic acid self-assembled monolayer for trace determination of phosphate in blood serum by using CV, EIS, and OSWV.

    PubMed

    Shervedani, Reza Karimi; Pourbeyram, Sima

    2009-03-15

    Preparation, characterization, and application of a new sensor for the determination of phosphate in blood serum is described by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and osteryoung square wave voltammetry (OSWV) in the presence of an appropriate redox reaction probe. The sensor was based on ionic adsorption of phosphate on Zr(IV) immobilized on gold-mercaptopropionic acid self-assembled monolayer (Au-MPA-Zr(IV) SAM) electrode. Parameters influencing the method were optimized. A linear range calibration curve from 1.0 x 10(-7) to 1.0 x 10(-6)M PO(4)(3-) with a detection limit of 5.30 x 10(-8)M and mean of relative standard deviations (R.S.D.) of 2.75% for n=4 was observed in the best conditions by OSWV. Possible interferences from the coexisting ions were also investigated. The results demonstrated that sensor could be used for the determination of phosphate in the presence of various ions. Regeneration of the surface was carried out successfully by 5-min sonication in 0.1M KOH solution and then 1-min incubation in 1.0x10(-3)M Zr(IV) with a good reproducibility, R.S.D.=1.47% for n=4 by OSWV. The validity of the method and applicability of the sensor were successfully tested by detection of phosphate in blood serum after deproteinization of sample without interference from sample matrix. The long-term storage stability of the electrode was studied. The experimental data is presented and discussed from which the new sensor is characterized.

  12. EIS and XPS investigations on the corrosion mechanism of ternary Zn-Co-Mo alloy coatings in NaCl solution

    NASA Astrophysics Data System (ADS)

    Winiarski, J.; Tylus, W.; Szczygieł, B.

    2016-02-01

    The changes in composition of the corrosion products of electrodeposited ternary Zn-Co-Mo alloy coatings on AISI 1015 steel during exposure to 0.5 mol dm-3 NaCl solution were investigated. XPS studies demonstrated that at the initial stage of corrosion on the surface of Zn-Co-Mo coating zinc hydroxide layer is formed. Hydroxyl groups react with chloride and carbonate ions which lead to the formation of zinc hydroxy carbonates and zinc hydroxy chlorides. The share of these compounds in the oxidation products is initially large. However, with time zinc hydroxy compounds slowly changes to zinc oxide, which is more stable corrosion product. It was estimated that after 24 h of exposure to NaCl solution nearly 60% of zinc detected on the surface of Zn-Co-Mo coating was present in the ZnO form, 18% in the form of zinc hydroxy chloride, and more than 21% as zinc hydroxy carbonate. XPS analyses revealed that the amount of zinc hydroxy chloride increases as the exposure time lengthens and it is significantly higher than at the surface of binary Zn-Co coating. The presence of crystalline zinc chloride hydroxide as a stable product of corrosion of ternary Zn-Co-Mo alloy coating in a 0.5 mol dm-3 NaCl solution was confirmed by XRD analysis. According to XRD and FTIR other zinc corrosion products like: ZnO, Zn(OH)2 and Zn5(CO3)2(OH)6 were also present. The results of XPS and EIS measurements allow us to assume that in the presence of Mo in the alloy, on the surface of ternary Zn-Co-Mo alloy (3.4 wt.% Co, 2.7 wt.% Mo) coating more zinc hydroxy chloride is formed, which favors higher corrosion resistance of this coating.

  13. CAST/EiJ and C57BL/6J Mice Differ in Their Oral and Postoral Attraction to Glucose and Fructose.

    PubMed

    Sclafani, Anthony; Vural, Austin S; Ackroff, Karen

    2017-03-01

    A recent study indicated that CAST/EiJ and C57BL/6J mice differ in their taste preferences for maltodextrin but display similar sucrose preferences. The present study revealed strain differences in preferences for the constituent sugars of sucrose. Whereas B6 mice preferred 8% glucose to 8% fructose in 2-day tests, the CAST mice preferred fructose to glucose. These preferences emerged with repeated testing which suggested post-oral influences. In a second experiment, 2-day choice tests were conducted with the sugars versus a sucralose + saccharin (SS) mixture which is highly preferred in brief access tests. B6 mice strongly preferred glucose but not fructose to the non-nutritive SS whereas CAST mice preferred SS to both glucose and fructose even when food restricted. This implied that CAST mice are insensitive to the postoral appetite stimulating actions of the 2 sugars. A third experiment revealed, however, that intragastric glucose and fructose infusions conditioned significant but mild flavor preferences in CAST mice, whereas in B6 mice glucose conditioned a robust preference but fructose was ineffective. Thus, unlike other mouse strains and rats, glucose is not more reinforcing than fructose in CAST mice. Their oral preference for fructose over glucose may be related to a subsensitive maltodextrin receptor or glucose-specific receptor which is stimulated by glucose but not fructose. The failure of CAST mice to prefer glucose to a non-nutritive sweetener distinguishes this strain from other mouse strains and rats. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  14. The Climate and its Impacts on deterioration and weathering rate of EI-Nadura Temple in El- Kharga Oasis, Western Desert of Egypt.

    NASA Astrophysics Data System (ADS)

    Ismael, Hossam

    2015-04-01

    Undoubtedly, El-Kharga Oasis monumental sites are considered an important part of our world's cultural heritage in the South Western Desert of Egypt. These sites are scattered on the floor of the oasis representing ancient civilizations. The Roman stone monuments in Kharga represent cultural heritage of an outstanding universal value. Such those monuments have suffered weathering deterioration. There are various elements which affect the weathering process of stone monuments: climate conditions, shapes of cultural heritages, exposed time periods, terrains, and vegetation around them, etc. Among these, climate conditions are the most significant factor affecting the deterioration of Archeological sites in Egypt. El- Kharga Oasis belongs administratively to the New Valley Governorate. It is located in the southern part of the western desert of Egypt, lies between latitudes 22°30'14" and 26°00'00" N, and between 30°27'00" and 30°47'00" E. The area of El Kharga Oasis covers about 7500 square kilometers. Pilot studies were carried out on the EI-Nadura Temple, composed of sandstones originating from the great sand sea. The major objective of this study is to monitor and measure the weathering features and the weathering rate affecting the building stones forming El-Nadora Roman building rocks in cubic cm. To achieve these aims, the present study used analysis of climatic data such as annual and seasonal solar radiation, Monthly average number of hours of sunshine, maximum and minimum air temperatures, wind speed, which have obtained from actual field measurements and data Meteorological Authority of El-Kharga station for the period 1977 to 2010 (33 years), and from the period 1941-2050 (110 years) as a long term of temperature data. Several samples were collected and examined by polarizing microscopy (PLM), X-ray diffraction analysis (XRD) and scanning electron microscopy equipped with an energy dispersive X-ray analysis system (SEM-EDX). The results were in

  15. Synthesis of 2-deoxy-2,2-difluoro-α-maltosyl fluoride and its X-ray structure in complex with Streptomyces coelicolor GlgEI-V279S.

    PubMed

    Thanna, Sandeep; Lindenberger, Jared J; Gaitonde, Vishwanath V; Ronning, Donald R; Sucheck, Steven J

    2015-07-21

    Streptomyces coelicolor (Sco) GlgEI is a glycoside hydrolase involved in α-glucan biosynthesis and can be used as a model enzyme for structure-based inhibitor design targeting Mycobacterium tuberculosis (Mtb) GlgE. The latter is a genetically validated drug target for the development of anti-Tuberculosis (TB) treatments. Inhibition of Mtb GlgE results in a lethal buildup of the GlgE substrate maltose-1-phosphate (M1P). However, Mtb GlgE is difficult to crystallize and affords lower resolution X-ray structures. Sco GlgEI-V279S on the other hand crystallizes readily, produces high resolution X-ray data, and has active site topology identical to Mtb GlgE. We report the X-ray structure of Sco GlgEI-V279S in complex with 2-deoxy-2,2-difluoro-α-maltosyl fluoride (α-MTF, 5) at 2.3 Å resolution. α-MTF was designed as a non-hydrolysable mimic of M1P to probe the active site of GlgE1 prior to covalent bond formation without disruption of catalytic residues. The α-MTF complex revealed hydrogen bonding between Glu423 and the C1F which provides evidence that Glu423 functions as proton donor during catalysis. Further, hydrogen bonding between Arg392 and the axial C2 difluoromethylene moiety of α-MTF was observed suggesting that the C2 position tolerates substitution with hydrogen bond acceptors. The key step in the synthesis of α-MDF was transformation of peracetylated 2-fluoro-maltal 1 into peracetylated 2,2-difluoro-α-maltosyl fluoride 2 in a single step via the use of Selectfluor®.

  16. Synthesis of 2-deoxy-2,2-difluoro-α-maltosyl fluoride and its X-ray structure in complex with Streptomyces coelicolor GlgEI-V279S

    SciTech Connect

    Thanna, Sandeep; Lindenberger, Jared J.; Gaitonde, Vishwanath V.; Ronning, Donald R.; Sucheck, Steven J.

    2015-06-05

    Streptomyces coelicolor (Sco) GlgEI is a glycoside hydrolase involved in α-glucan biosynthesis and can be used as a model enzyme for structure-based inhibitor design targeting Mycobacterium tuberculosis (Mtb) GlgE. The latter is a genetically validated drug target for the development of anti-Tuberculosis (TB) treatments. Inhibition of Mtb GlgE results in a lethal buildup of the GlgE substrate maltose-1-phosphate (M1P). However, Mtb GlgE is difficult to crystallize and affords lower resolution X-ray structures. Sco GlgEI-V279S on the other hand crystallizes readily, produces high resolution X-ray data, and has active site topology identical to Mtb GlgE. We report the X-ray structure of Sco GlgEI-V279S in complex with 2-deoxy-2,2-difluoro-α-maltosyl fluoride (α-MTF, 5) at 2.3 Å resolution. α-MTF was designed as a non-hydrolysable mimic of M1P to probe the active site of GlgE1 prior to covalent bond formation without disruption of catalytic residues. The α-MTF complex revealed hydrogen bonding between Glu423 and the C1F which provides evidence that Glu423 functions as proton donor during catalysis. Further, hydrogen bonding between Arg392 and the axial C2 difluoromethylene moiety of α-MTF was observed suggesting that the C2 position tolerates substitution with hydrogen bond acceptors. The key step in the synthesis of α-MDF was transformation of peracetylated 2-fluoro-maltal 1 into peracetylated 2,2-difluoro-α-maltosyl fluoride 2 in a single step via the use of Selectfluor®

  17. A chemical, morphological, and electrochemical (XPS, SEM/EDX, CV, and EIS) analysis of electrochemically modified electrode surfaces of natural chalcopyrite (CuFeS2) and pyrite (FeS2) in alkaline solutions.

    PubMed

    Velásquez, Pablo; Leinen, Dietmar; Pascual, José; Ramos-Barrado, José Ramón; Grez, Paula; Gómez, Humberto; Schrebler, Ricardo; Del Río, Rodrigo; Córdova, Ricardo

    2005-03-24

    Electrodic surfaces of natural chalcopyrite and natural pyrite minerals (El Teniente mine, Chile) have been studied by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), X-ray photoelectron spectroscopy (XPS), and scanning electron microscopy including microanalysis (SEM/EDX). For comparison, fractured and polished mineral surfaces were also studied by XPS. In both electrodes, the formation of Fe(III) species containing oxygen were detected and Cu(II) species containing oxygen were additionally detected for chalcopyrite at advanced oxidation states. The presence of Cu(II) species containing oxygen was not detected by XPS for the initial oxidation states of the chalcopyrite. For pyrite, the present results do not allow confirmation of the presence of polysulfurs such as have been previously proposed. In both minerals, the measurements of SEM and EDX show relevant alterations in the respective surfaces when different potential values were applied. The chalcopyrite surface shows the formation of protrusions with a high concentration of oxygen. The pyrite surface shows a layer of modified material with high oxygen content. The modifications detected by XPS, SEM, and EDX allowed the explanation of the complexity of the equivalent circuit used to simulate the experimental EIS data. At high oxidation states, both minerals showed a pseudoinductive loop in the equivalent circuit, which was due to the active electrodissolution of the minerals which takes place through a surface film previously formed.

  18. Application of EIS and SECM Studies for Investigation of Anticorrosion Properties of Epoxy Coatings Containing Zinc Oxide Nanoparticles on Mild Steel in 3.5% NaCl Solution

    NASA Astrophysics Data System (ADS)

    Raj, X. Joseph

    2017-07-01

    The effect of corrosion protection performance of epoxy coatings containing ZnO nanoparticle on mild steel in 3.5% NaCl solution was analyzed using scanning electrochemical microscopy and electrochemical impedance spectroscopy (EIS). Line profile and topographic image analysis were measured by applying -0.70 and +0.60 V as the tip potential for the cathodic and anodic reactions, respectively. The tip current at -0.70 V for the epoxy-coated sample with ZnO nanoparticles decreased rapidly, which is due to cathodic reduction in dissolved oxygen. The EIS measurements were taken in 3.5% NaCl after wet and dry cyclic corrosion test. The increase in the film resistance ( R f) and charge transfer resistance ( R ct) values was confirmed by the addition of ZnO nanoparticles in the epoxy coating. SEM/EDX analysis showed that complex oxide layer of zinc was enriched in corrosion products at a scratched area of the coated steel after corrosion testing. FIB-TEM analysis confirmed the presence of the nanoscale complex oxide layer of Zn in the rust of the steel that had a beneficial effect on the corrosion resistance of coated steel by forming protective corrosion products in the wet/dry cyclic test.

  19. Electrodeposition of platinum-iridium coatings and nanowires for neurostimulating applications: Fabrication, characterization and in-vivo retinal stimulation/recording. EIS studies of hexavalent and trivalent chromium based military coating systems

    NASA Astrophysics Data System (ADS)

    Petrossians, Artin

    The studies presented in this thesis are composed of two different projects demonstrated in two different parts. The first part of this thesis represents an electrochemical approach to possible improvements of the interface between an implantable device and biological tissue. The second part of this thesis represents electrochemical impedance spectroscopy (EIS) studies on the corrosion resistance behavior of different types of polymer coated Al2024 alloys. In the first part of this thesis, a broad range of investigations on the development of an efficient and reproducible electrochemical deposition method for fabrication of thin-film platinum-iridium alloys were performed. The developed method for production of dense films was then modified to produce very high surface area coatings with ultra-low electrochemical impedance characteristics. The high-surface area platinum-iridium coating was applied on microelectrode arrays for chronic in-vitro stimulation. Using the same method of producing dense films, platinum-iridium nanowires were fabricated using Anodized Aluminum Oxide (AAO) templates for hermetic packaging applications to be used in implantable microelectronics. The implantable microelectronics will be used to perform data reception and transmission management, power recovery, digital processing and analog output of stimulus current. Finally, in-vivo electrical stimulation tests were performed on an animal retina using high surface-area platinum-iridium coated single microelectrodes to verify the charge transfer characteristics of the coatings. In the second part of this thesis, three different sets of samples with different combinations of pretreatments, primers with the same type of topcoat were tested in 0.5 N NaCl for period of 30 days. The surface changes measured by EIS as a function of time were then analyzed. The analysis of the fit parameters of the impedance spectra showed that the different primers had the most effect on the corrosion protection

  20. Hair analysis for delta(9)-THC, delta(9)-THC-COOH, CBN and CBD, by GC/MS-EI. Comparison with GC/MS-NCI for delta(9)-THC-COOH.

    PubMed

    Baptista, Maria João; Monsanto, Paula Verâncio; Pinho Marques, Estela Gouveia; Bermejo, Ana; Avila, Sofia; Castanheira, Alice Martelo; Margalho, Cláudia; Barroso, Mário; Vieira, Duarte Nuno

    2002-08-14

    A sensitive analytical method was developed for quantitative analysis of delta(9)-tetrahydrocannabinol (delta(9)-THC), 11-nor-delta(9)-tetrahydrocannabinol-carboxylic acid (delta(9)-THC-COOH), cannabinol (CBN) and cannabidiol (CBD) in human hair. The identification of delta(9)-THC-COOH in hair would document Cannabis use more effectively than the detection of parent drug (delta(9)-THC) which might have come from environmental exposure. Ketamine was added to hair samples as internal standard for CBN and CBD. Ketoprofen was added to hair samples as internal standard for the other compounds. Samples were hydrolyzed with beta-glucuronidase/arylsulfatase for 2h at 40 degrees C. After cooling, samples were extracted with a liquid-liquid extraction procedure (with chloroform/isopropyl alcohol, after alkalinization, and n-hexane/ethyl acetate, after acidification), which was developed in our laboratory. The extracts were analysed before and after derivatization with pentafluoropropionic anhydride (PFPA) and pentafluoropropanol (PFPOH) using a Hewlett Packard gas chromatographer/mass spectrometer detector, in electron impact mode (GC/MS-EI). Derivatized delta(9)-THC-COOH was also analysed using a Hewlett Packard gas chromatographer/mass spectrometer detector, in negative ion chemical ionization mode (GC/MS-NCI) using methane as the reagent gas. Responses were linear ranging from 0.10 to 5.00 ng/mg hair for delta(9)-THC and CBN, 0.10-10.00 ng/mg hair for CBD, 0.01-5.00 ng/mg for delta(9)-THC-COOH (r(2)>0.99). The intra-assay precisions ranged from <0.01 to 12.40%. Extraction recoveries ranged from 80.9 to 104.0% for delta(9)-THC, 85.9-100.0% for delta(9)-THC-COOH, 76.7-95.8% for CBN and 71.0-94.0% for CBD. The analytical method was applied to 87 human hair samples, obtained from individuals who testified in court of having committed drug related crimes. Quantification of delta(9)-THC-COOH using GC/MS-NCI was found to be more convenient than GC/MS-EI. The latter may give rise

  1. An unusual case of death: suffocation caused by leaves of common ivy (Hedera helix). Detection of hederacoside C, alpha-hederin, and hederagenin by LC-EI/MS-MS.

    PubMed

    Gaillard, Yvan; Blaise, Pierre; Darré, Alexandre; Barbier, Thierry; Pépin, Gilbert

    2003-01-01

    We report one fatal case of asphyxia caused by leaves of common ivy. Macroscopic examination of the corpse during the autopsy disclosed an incredible quantity of leaves of Hedera helix in the mouth and throat of the decedent. In order to rule out the possibility of poisoning by the toxic saponins contained in the plant, we have developed an efficient LC-EI/MS-MS assay of hederacoside C, alppha-hederin, and hederagenin in biological fluids and plant material. Sample cleanup involved solid-phase extraction of the toxins on C18 cartridges followed by LC analysis under reversed-phase conditions in the gradient elution mode. Solute identification was performed using full scan MS-MS spectrum of the analytes. Oleandrine was used as internal standard. Under these conditions, saponins in powdered dried leaves of Hedera helix were measured at a concentration of 21.83 mg/g for hederacoside C, 0.41 mg/g for alpha-hederin and 0.02 mg/g for hederagenin. No toxin was detected in cardiac blood, femoral blood, or urine of the deceased, but hederacoside C was quantitated at 857 ng/mL in the gastric juice. These findings led us to conclude that the man committed suicide and that the death was caused by suffocation by leaves of common ivy.

  2. Electrochemical characterization of a low modulus Ti-35.5Nb-7.3Zr-5.7Ta alloy in a simulated body fluid using EIS for biomedical applications

    SciTech Connect

    Bhola, R.; Bhola, S. M.; Mishra, B.; Ayers, R. A.; Olson, D. L.

    2011-06-23

    Electrochemical characterization of the low modulus Ti-35.5Nb-7.3Zr-5.7Ta beta alloy (TNZT) has been performed in phosphate buffer saline solution at 37 deg. C using the non destructive electrochemical impedance spectroscopy technique. Measurements were performed at various immersion intervals at the open circuit potential (OCP), which was also monitored with time. Results obtained for TNZT alloy have been compared with those for the commercially used Ti-6Al-4V mixed alloy (Ti64) and the commercially pure titanium (Ti2) alpha alloy. Potentiodynamic polarization was performed to supplement the data obtained from EIS analysis. The TNZT alloy exhibits a two time constant impedance response, whereas the Ti64 and Ti2 alloys display a one time constant behavior. Human fetal osteoblast cells show a better adhesion and a higher cell count for the TNZT alloy compared to the other two alloys. The present investigation is an effort to understand the correlation between the electrochemical, morphological and cellular characteristics of titanium alloys to qualify them for implant applications.

  3. Post-acquisition data processing for the screening of transformation products of different organic contaminants. Two-year monitoring of river water using LC-ESI-QTOF-MS and GCxGC-EI-TOF-MS.

    PubMed

    López, S Herrera; Ulaszewska, M M; Hernando, M D; Martínez Bueno, M J; Gómez, M J; Fernández-Alba, A R

    2014-11-01

    This study describes a comprehensive strategy for detecting and elucidating the chemical structures of expected and unexpected transformation products (TPs) from chemicals found in river water and effluent wastewater samples, using liquid chromatography coupled to electrospray ionization quadrupole-time-of-flight mass spectrometer (LC-ESI-QTOF-MS), with post-acquisition data processing and an automated search using an in-house database. The efficacy of the mass defect filtering (MDF) approach to screen metabolites from common biotransformation pathways was tested, and it was shown to be sufficiently sensitive and applicable for detecting metabolites in environmental samples. Four omeprazole metabolites and two venlafaxine metabolites were identified in river water samples. This paper reports the analytical results obtained during 2 years of monitoring, carried out at eight sampling points along the Henares River (Spain). Multiresidue monitoring, for targeted analysis, includes a group of 122 chemicals, amongst which are pharmaceuticals, personal care products, pesticides and PAHs. For this purpose, two analytical methods were used based on direct injection with a LC-ESI-QTOF-MS system and stir bar sorptive extraction (SBSE) with bi-dimensional gas chromatography coupled with a time-of-flight spectrometer (GCxGC-EI-TOF-MS).

  4. Co-extraction and simultaneous determination of multi-class hydrophobic organic contaminants in marine sediments and biota using GC-EI-MS/MS and LC-ESI-MS/MS.

    PubMed

    Zhang, Hui; Bayen, Stéphane; Kelly, Barry C

    2015-10-01

    A multi-residue analytical method was developed involving co-extraction and simultaneous determination of 89 hydrophobic organic contaminants (HOCs) in marine sediments and biota using gas chromatography-electron ionization-triple quadrupole mass spectrometry (GC-EI-MS/MS) and liquid chromatography-electrospray ionization-triple quadrupole mass spectrometry (LC-ESI-MS/MS). Target analytes include polychlorinated biphenyls (PCBs), pesticides, chlorobenzenes, brominated and chlorinated flame retardants, nitro-aromatic and polycyclic musks, triclosan and methyl triclosan. Spike-recovery experiments showed relative recoveries of analytes were generally between 70% and 130%. Analyses of a sediment standard reference material (SRM 1944) demonstrated recoveries between 80% and 120% for certified concentrations of individual PCBs and pesticides. Method detection limits of individual compounds ranged from 0.1 to 57.1 pg/g dw for sediments and 0.1 to 22.8 pg/g ww for biota. A field survey of sediments and biota from Singapore's marine environment demonstrated the occurrence of polycyclic and nitro-aromatic musks (galaxolide, tonalide, musk ketone, etc.), halogenated flame retardants (syn- and anti-dechlorane plus (DP), α, β and γ-hexabromocyclododecane (HBCD), tetrabromobisphenol A (TBBPA), etc.), as well as triclosan and methyl triclosan. Galaxolide exhibited relatively high concentrations, with highest levels in polychaete worms (161.7±72.5 ng/g ww) and clams (546.8±220.3 ng/g ww) from mangroves. Triclosan and methyl triclosan levels were highly correlated in sediments (r(2)=0.9752), while syn- and anti-DP were strongly correlated in biota (r(2)=0.9279). anti-DP/syn-DP stereoisomer ratios were typically >1 and ranged between 0.94 and 29.2 in sediments and biota samples. γ-HBCD exhibited the highest concentrations among HBCD isomers in sediments. Conversely, α-HBCD was the dominant HBCD isomer in biota.

  5. Using present-day patterns of interseismic coupling to model the C.E. 1707 Hōei earthquake and simulate tsunami inundation of Lake Ryuuoo in the Bungo Channel, southwestern Japan

    NASA Astrophysics Data System (ADS)

    Baranes, H. E.; Woodruff, J. D.; Loveless, J. P.; Cheng, W.; Weiss, R.; Kanamaru, K.

    2015-12-01

    The C.E. 1707 Hōei event is often considered the worst-case scenario for a Nankai Trough earthquake and tsunami impacting southwestern Japan, and recent estimates of the earthquake's magnitude have exceeded MW 9. However, when paired with tsunami simulations, previously published earthquake models for the event fail to match sedimentological and historical records of 1707 tsunami height in Shikoku and Kyushu. Specifically, models do not produce a sufficiently large tsunami in the northern Bungo Channel and Seto Inland Sea without also over-predicting tsunami heights along the open Pacific coastlines of Shikoku and Kyushu. Here, we apply a newly developed rupture model that uses present-day patterns of geodetically imaged interseismic coupling to inform patterns in coseismic slip. Along the southwestern extent of the plate interface (the Hyuga-nada area), there is a region of weak coupling up-dip along the trench axis and a region of strong coupling down-dip beneath Shikoku and Kyushu. Following this pattern, the new earthquake model produces less coseismic uplift offshore and greater subsidence in an inland region that includes the Bungo Channel. This combination of regional subsidence and a tsunami wave more focused to the Bungo Channel results in inundation patterns more consistent with historical and sedimentological observations in the Hyuga-nada area. We also run the tsunami simulation on a high-resolution grid around Lake Ryuuoo, a back-barrier lake in the northern Bungo Channel that contains a marine overwash deposit from the 1707 tsunami. We apply a simple sediment transport model to demonstrate that the coupling-based rupture scenario produces flow over Lake Ryuuoo's barrier capable of transporting the maximum grain size observed in the lake's 1707 deposit. These findings suggest that spatial trends in our present-day coupling model are more consistent with inundation patterns observed for large tsunamis generated by coseismic rupture along the Nankai

  6. 32 CFR 989.20 - Final EIS.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE ENVIRONMENTAL PROTECTION... Force responses, and errata sheets of changes staffed to the HQ USAF ESOHC for coordination. However... these modifications for coordination within the Air Force. Regardless of which procedure is followed...

  7. 32 CFR 989.20 - Final EIS.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE ENVIRONMENTAL PROTECTION... Force responses, and errata sheets of changes staffed to the HQ USAF ESOHC for coordination. However... these modifications for coordination within the Air Force. Regardless of which procedure is followed...

  8. 32 CFR 989.20 - Final EIS.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE ENVIRONMENTAL PROTECTION... Force responses, and errata sheets of changes staffed to the HQ USAF ESOHC for coordination. However... these modifications for coordination within the Air Force. Regardless of which procedure is followed...

  9. 32 CFR 989.20 - Final EIS.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE ENVIRONMENTAL PROTECTION... Force responses, and errata sheets of changes staffed to the HQ USAF ESOHC for coordination. However... these modifications for coordination within the Air Force. Regardless of which procedure is followed...

  10. Exploiting EIS/Hinode Imaging Diagnostic Capabilities

    NASA Astrophysics Data System (ADS)

    Ugarte-Urra, Ignacio; Warren, H. P.

    2009-05-01

    Using a wide slit, also called slot, the Extreme-ultraviolet Imaging Spectrometer, on-board Hinode, is capable of obtaining relatively fast (1-3 min) simultaneous monochromatic images of various spectral lines with different formation temperatures ranging 0.4-3 MK. This mode allows us to study morphology and dynamics of solar coronal and transition region structures across the temperature spectrum in a similar way to an EUV imager. This is achieved at the expense of spectral resolution. In this paper we investigate the plasma diagnostic capabilities of these spectrally pure images.Wide slit images can be interpreted as a superposition of simultaneous narrow slit spectra from adjacent solar positions. From the comparison of consecutive narrow slit rasters and wide slit images, we demonstrate that by making simple assumptions it is possible to extract the narrow slit spectra out of the slot images. This encouraging result opens up the door for plasma diagnostics, like electron density from spectral line ratios and differential emission measure analysis, for solar dynamic events. Various examples, as well as the limitations and validity of the assumptions, are discussed.

  11. CON4EI: CONsortium for in vitro Eye Irritation testing strategy - EpiOcular™ time-to-toxicity (EpiOcular ET-50) protocols for hazard identification and labelling of eye irritating chemicals.

    PubMed

    Kandarova, Helena; Letasiova, Silvia; Adriaens, Els; Guest, Robert; Willoughby, Jamin A; Drzewiecka, Agnieszka; Gruszka, Katarzyna; Alépée, Nathalie; Verstraelen, Sandra; Van Rompay, An R

    2017-08-30

    Assessment of acute eye irritation potential is part of the international regulatory requirements for testing of chemicals. The objective of the CON4EI (CONsortium for in vitro Eye Irritation testing strategy) project was to develop tiered testing strategies for eye irritation assessment for all drivers of classification. A set of 80 reference chemicals (38 liquids and 42 solids) was tested with eight different alternative methods. Here, the results obtained with reconstructed human cornea-like epithelium (RhCE) EpiOcular™ in the EpiOcular time-to-toxicity Tests (Neat and Dilution ET-50 protocols) are presented. The primary aim of this study was to evaluate whether test methods can discriminate chemicals not requiring classification for serious eye damage/eye irritancy (No Category) from chemicals requiring classification and labelling for Category 1 and Category 2. In addition, the predictive capacity in terms of in vivo drivers of classification was investigated. The chemicals were tested in two independent runs by MatTek In Vitro Life Science Laboratories. Results of this study demonstrate very high specificity of both test protocols. With the existing prediction models described in the SOPs, the specificity of the Neat and Dilution method was 87% and 100%, respectively. The Dilution method was able to correctly predicting 66% of GHS Cat 2 chemicals, however, prediction of GHS Cat 1 chemicals was only 47%-55% using the current protocols. In order to achieve optimal prediction for all three classes, a testing strategy was developed which combines the most predictive time-points of both protocols and for tests liquids and solids separately. Using this new testing strategy, the sensitivity for predicting GHS Cat 1 and GHS Cat 2 chemicals was 73% and 64%, respectively and the very high specificity of 97% was maintained. None of the Cat 1 chemicals was underpredicted as GHS No Category. Further combination of the EpiOcular time-to-toxicity protocols with other

  12. Impact of the electrochemical porosity and chemical composition on the lithium ion exchange behavior of polypyrroles (ClO4-, TOS-, TFSI-) prepared electrochemically in propylene carbonate. comparative EQCM, EIS and CV studies.

    PubMed

    Dziewoński, Paweł Marek; Grzeszczuk, Maria

    2010-06-03

    the as grown PPy film occurs at initial cycles of the cation uptake causing irreversible swelling of the polymer phase. Mechanisms of the redox process and accompanying mass transport involving PPy films were investigated using comparatively three techniques: cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and electrochemical quartz crystal microbalance (EQCM).

  13. Supplement Analysis for the Watershed Management Program EIS (DOE/EIS-0265/SA-153)

    SciTech Connect

    Stewart, Shannon C.

    2004-07-06

    The Bonneville Power Administration is proposing to fund a fish passage improvement effort on Cowiche Creek in conjunction with the Yakima Tributary Access and Habitat Program and the North Yakima Conservation District. As part of this project, existing pump diversions will be fitted with Washington Department of Fish and Wildlife and NOAA Fisheries approved Pump Rite screens. In each case, the intake will be attached to a flexible plastic pipe that may be draped over the streambank and lowered into the creek during the irrigation season. No filling or excavating will be required and no permanent structures are to be installed. Existing diversions currently use removable flex hose, so there are no existing structures to be removed.

  14. Supplement Analysis for the Wildlife Management Program EIS (DOE/EIS-0246/SA-38)

    SciTech Connect

    N /A

    2004-01-14

    BPA proposes to purchase the conservation easements on the Sanders (307 acres) and Seabaugh (449 acres) parcels of the Weaver Slough to ensure that current fisheries and natural resource values remain protected, and that no development or human encroachment would occur on these parcels, in perpetuity. No planned construction or improvements are currently proposed and the project does not involve fee title land acquisition. Protection will sustain quality aquatic habitats, water quality, and fish and wildlife habitat. Wetlands protected by this easement are priority wetlands in the basin, according to the Flathead Lakers Critical Lands Study. A ''Grant of Agricultural Conservation Easement'' has been prepared for both the Sanders parcel (Nov. 21, 2003) and Seabaugh parcel (December 4, 2003) which provide the parameters, rights and responsibilities, prohibitions, contingencies, and other provisions for the granting these properties for the above purpose and intent. In addition, a Memorandum of Agreement (among the Montana Department of Fish, Wildlife and Parks; Flathead Land Trust; and BPA) has also been established to protect and conserve the Sanders and Seabaugh parcels.

  15. Supplement Analysis for the Wildlife Mitigation Program EIS (DOE/EIS-0246/SA-32)

    SciTech Connect

    N /A

    2003-05-20

    BPA proposes to purchase a conservation easement on the Zumwalt Prairie Preserve, which is currently owned by The Nature Conservancy. The Zumwalt Prairie Preserve encompasses 27,000 acres in Wallowa County, Oregon and is the largest and most intact palouse bunchgrass prairie in North America. The conservation easement will guarantee that the wildlife and fishery values of this property are permanently maintained. The goal of the easement is to protect the ecological condition and natural function of the Preserve's aquatic and terrestrial habitats and the species it supports by protecting it's natural resources, maintaining or enhancing its air and water quality, and preserving its underlying archaeological and cultural aspects in perpetuity.

  16. Supplement Analysis for the Wildlife Mitigation Program EIS (DOE/EIS-0246/SA-37)

    SciTech Connect

    N /A

    2004-01-16

    BPA proposes to fund the purchase of four parcels of land within the boundaries of the Spokane Indian Reservation, totaling approximately 860 acres. Title to the land will pass to the Spokane Tribe of Indians. The goal of the property acquisition is to dedicate the land to the protection, mitigation, and enhancement of fish and wildlife affected by the construction and operation of portions of the Federal Columbia River Power System.

  17. Supplement Analysis for the Wildlife Mitigation Program EIS (DOE/EIS-0246/SA-35)

    SciTech Connect

    N /A

    2003-08-27

    BPA proposes to purchase a conservation easement on the Zumwalt Prairie Preserve, which is currently owned by The Nature Conservancy. The Zumwalt Prairie Preserve encompasses 27,000 acres in Wallowa County, Oregon and is the largest and most intact palouse bunchgrass prairie in North America. The conservation easement will guarantee that the wildlife and fishery values of this property are permanently maintained. The goal of the easement is to protect the ecological condition and natural function of the Preserve's aquatic and terrestrial habitats and the species it supports by protecting it's natural resources, maintaining or enhancing its air and water quality, and preserving its underlying archaeological and cultural aspects in perpetuity.

  18. Supplement Analysis for the Wildlife Mitigation Program EIS (DOE/EIS-0246/SA-40)

    SciTech Connect

    N /A

    2004-07-16

    BPA proposes to fund the acquisition of two parcels in Benewah County, Idaho with the Coeur d'Alene Tribe. These parcels encompass approximately 475 acres of riparian and potential riparian habitat along Hangman Creek on the Coeur d'Alene Indian Reservation. The goal of this project is to protect, mitigate, and enhance wildlife affected by the construction and operation of the Federal hydroelectric facilities on the Columbia River. The current proposal includes only the fee title acquisition of these parcels; habitat enhancement activities will likely be carried out by the Coeur d'Alene Tribe in the future following the development of a management plan(s) for the lands.

  19. Supplement Analysis for the Wildlife Mitigation Program EIS (DOE/EIS-0246/SA-39)

    SciTech Connect

    N /A

    2004-02-02

    BPA funds the Albeni Falls Wildlife Mitigation Program, which is tasked with the acquisition and restoration of key habitats within the Pend Oreille Watershed. This mitigation program purchases private land to be owned and managed by program participants for the protection, mitigation, and enhancement of wildlife affected by the construction and operation of the Federal hydroelectric facilities on the Columbia River. BPA is currently working with the Kalispel Tribe of Indians to acquire and manage three parcels that total approximately 890 acres of land within Pend Oreille County, Washington. The properties proposed for acquisition contain habitats or potential habitats that will provide BPA with credits for partial mitigation of wildlife habitat losses due to the construction of Albeni Falls Dam. The current proposal includes only the fee title acquisition of these parcels; habitat enhancement activities will likely be carried out by the Kalispel Tribe of Indians in the future following the development of a management plan(s) for the lands.

  20. Supplement Analysis for the Wildlife Mitigation Program EIS (DOE/EIS-0246/SA-34)

    SciTech Connect

    N /A

    2003-08-22

    BPA proposes to purchase a conservation easement on the Zumwalt Prairie Preserve, which is currently owned by The Nature Conservancy. The Zumwalt Prairie Preserve encompasses 27,000 acres in Wallowa County, Oregon and is the largest and most intact palouse bunchgrass prairie in North America. The conservation easement will guarantee that the wildlife and fishery values of this property are permanently maintained. The goal of the easement is to protect the ecological condition and natural function of the Preserve's aquatic and terrestrial habitats and the species it supports by protecting it's natural resources, maintaining or enhancing its air and water quality, and preserving its underlying archaeological and cultural aspects in perpetuity.

  1. Supplement Analysis for the Wildlife Mitigation Program EIS (DOE/EIS-0246/SA-33)

    SciTech Connect

    N /A

    2003-05-21

    BPA proposes to purchase a conservation easement on the Zumwalt Prairie Preserve, which is currently owned by The Nature Conservancy. The Zumwalt Prairie Preserve encompasses 27,000 acres in Wallowa County, Oregon and is the largest and most intact palouse bunchgrass prairie in North America. The conservation easement will guarantee that the wildlife and fishery values of this property are permanently maintained. The goal of the easement is to protect the ecological condition and natural function of the Preserve's aquatic and terrestrial habitats and the species it supports by protecting it's natural resources, maintaining or enhancing its air and water quality, and preserving its underlying archaeological and cultural aspects in perpetuity.

  2. Supplement Analysis for the Watershed Management Program EIS (DOE/EIS-0265/SA-67)

    SciTech Connect

    Stewart, Shannon C.

    2001-10-04

    BPA is proposing to provide cost share for a program that will protect ESA-listed salmonid species in the Walla Walla River Basin through the installation of Washington Department of Fish and Wildlife (WDFW) and National Marine Fisheries Service (NMFS) approved fish screens on up to 197 irrigation diversions in the basin. ESA-listed steelhead and bull trout are presently at risk in the Walla Walla Basin as the result of a combination of factors that primarily involve insufficient flow, extensive habitat degradation, and mortality from surface water diversions. Unscreened or improperly screened diversions can damage fish scaling and induce stress, both of which can be lethal. They are also known to cause migration delays and increased predation; impinge fish against screen surfaces; or, in cases where screen mesh size is too large, allow juvenile fish to be drawn directly into functioning irrigation systems resulting in direct mortality. The goal of this project is to eliminate imminent mortality risks to ESA-listed fish arising from inadequate irrigation diversions in the Walla Walla Basin by upgrading screens to current state and federal juvenile fish screen standards. This Supplement Analysis covers only those screen upgrades and/or installations that will meet the NMFS no effect standard (NMFS, January 16, 2001). All other screen upgrades and/or installations in the Walla Walla River Basin associated with this project will require additional NEPA analysis and documentation prior to implementation.

  3. Explanation of Significant Differences Between Models used to Assess Groundwater Impacts for the Disposal of Greater-Than-Class C Low-Level Radioactive Waste and Greater-Than-Class C-Like Waste Environmental Impact Statement (DOE/EIS-0375-D) and the

    SciTech Connect

    Annette Schafer; Arthur S. Rood; A. Jeffrey Sondrup

    2011-08-01

    Models have been used to assess the groundwater impacts to support the Draft Environmental Impact Statement for the Disposal of Greater-Than-Class C (GTCC) Low-Level Radioactive Waste and GTCC-Like Waste (DOE-EIS 2011) for a facility sited at the Idaho National Laboratory and the Environmental Assessment for the INL Remote-Handled Low-Level Waste Disposal Project (INL 2011). Groundwater impacts are primarily a function of (1) location determining the geologic and hydrologic setting, (2) disposal facility configuration, and (3) radionuclide source, including waste form and release from the waste form. In reviewing the assumptions made between the model parameters for the two different groundwater impacts assessments, significant differences were identified. This report presents the two sets of model assumptions and discusses their origins and implications for resulting dose predictions. Given more similar model parameters, predicted doses would be commensurate.

  4. Molecular and morphological data reveal three new cryptic species of Chiasmocleis (Mehely 1904) (Anura, Microhylidae) endemic to the Atlantic Forest, Brazil.

    PubMed

    Forlani, Mauricio C; Tonini, João F R; Cruz, Carlos A G; Zaher, Hussam; de Sá, Rafael O

    2017-01-01

    Three new cryptic species of Chiasmocleis from the Atlantic Forest of Brazil are described. Two of these species occur in the northeastern states of Sergipe and Bahia, whereas the third species is found in the southeastern state of São Paulo. The new species can be distinguished from other congeneric species by the molecular data, as evidenced in the phylogeny, and by a combination of morphological characters including: size, foot webbing, dermal spines, and coloration patterns. Chiasmocleis species differ in osteological traits, therefore we also provide an osteological description of each new species and comparsions with data reported for other species in the genus.

  5. Molecular and morphological data reveal three new cryptic species of Chiasmocleis (Mehely 1904) (Anura, Microhylidae) endemic to the Atlantic Forest, Brazil

    PubMed Central

    Forlani, Mauricio C.; Cruz, Carlos A.G.; Zaher, Hussam

    2017-01-01

    Three new cryptic species of Chiasmocleis from the Atlantic Forest of Brazil are described. Two of these species occur in the northeastern states of Sergipe and Bahia, whereas the third species is found in the southeastern state of São Paulo. The new species can be distinguished from other congeneric species by the molecular data, as evidenced in the phylogeny, and by a combination of morphological characters including: size, foot webbing, dermal spines, and coloration patterns. Chiasmocleis species differ in osteological traits, therefore we also provide an osteological description of each new species and comparsions with data reported for other species in the genus. PMID:28243531

  6. Emotional Intelligence (EI): A Therapy for Higher Education Students

    ERIC Educational Resources Information Center

    Machera, Robert P.; Machera, Precious C.

    2017-01-01

    This study investigates the need to design and develop emotional intelligence curriculum for students in higher education. Emotional intelligence curriculum may be used as a therapy that provides skills to manage high emotions faced by generation "Y", on a day-to-day basis. Generation "Y" is emotionally challenged with: drug…

  7. 28 CFR 91.64 - Supplemental EA or EIS.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ....64 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) GRANTS FOR CORRECTIONAL FACILITIES Environmental Impact Review Procedures for VOI/TIS Grant Program Environmental Review Procedures § 91.64... environmental assessments or draft or final environmental impact statements if the grantee proposes to make...

  8. 28 CFR 91.64 - Supplemental EA or EIS.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ....64 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) GRANTS FOR CORRECTIONAL FACILITIES Environmental Impact Review Procedures for VOI/TIS Grant Program Environmental Review Procedures § 91.64... environmental assessments or draft or final environmental impact statements if the grantee proposes to make...

  9. 28 CFR 91.64 - Supplemental EA or EIS.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ....64 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) GRANTS FOR CORRECTIONAL FACILITIES Environmental Impact Review Procedures for VOI/TIS Grant Program Environmental Review Procedures § 91.64... environmental assessments or draft or final environmental impact statements if the grantee proposes to make...

  10. 28 CFR 91.64 - Supplemental EA or EIS.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ....64 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) GRANTS FOR CORRECTIONAL FACILITIES Environmental Impact Review Procedures for VOI/TIS Grant Program Environmental Review Procedures § 91.64... environmental assessments or draft or final environmental impact statements if the grantee proposes to make...

  11. 28 CFR 91.64 - Supplemental EA or EIS.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ....64 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) GRANTS FOR CORRECTIONAL FACILITIES Environmental Impact Review Procedures for VOI/TIS Grant Program Environmental Review Procedures § 91.64... environmental assessments or draft or final environmental impact statements if the grantee proposes to make...

  12. 7 CFR 1940.329 - Commenting on other Agencies' EIS's.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF...) Comments should concentrate on those matters of primary importance to FmHA or its successor agency under Public Law 103-354 and on areas of Agency expertise, such as rural planning and development....

  13. Guidelines for Review of EA/EIS Documents.

    DTIC Science & Technology

    1980-08-01

    Solid Waste Disposal 3 Water Supply 4. Safety 5. Radiation 6. Stress 7. Disease 8. Electromagnetic Spectrum Air Quality 1. Generation and Dispersion of...5. Radiation 6. Stress I. Disease 8. Electromagnetic Spectrum Air Qualiy 1. Generation and Dispersion of Contaminants 2. Toxic Air Pollutants 3. Odor...ray), microwave , laser, or other (infrared, ultraviolet, and visible light) radiation, or high-tension electric wires? No: Continue to subarea 6. Yes

  14. 43 CFR 10010.10 - Whether to prepare an EIS.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... (CX) (40 CFR 1508.4). (1) The following criteria will be used to determine categories of actions to be... listed in subpart G of this part apply to individual actions subject to CX. Appropriate environmental...

  15. 43 CFR 10010.10 - Whether to prepare an EIS.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... (CX) (40 CFR 1508.4). (1) The following criteria will be used to determine categories of actions to be... listed in subpart G of this part apply to individual actions subject to CX. Appropriate environmental...

  16. 43 CFR 10010.10 - Whether to prepare an EIS.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... (CX) (40 CFR 1508.4). (1) The following criteria will be used to determine categories of actions to be... listed in subpart G of this part apply to individual actions subject to CX. Appropriate environmental...

  17. 7 CFR 650.7 - When to prepare an EIS.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... realignment or work to modify channel capacity by deepening or widening where significant aquatic or wildlife habitat exists. The EE will determine if the channel supports significant aquatic or wildlife habitat; (2... environment (40 CFR 1508.14)? For example, will it significantly alter or destroy valuable wetlands, important...

  18. 32 CFR 651.41 - Conditions requiring an EIS.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... cultural, archaeological, or scientific resources, public parks and recreation areas, wildlife refuge or... controversial from an environmental standpoint. (j) Cause loss or destruction of significant scientific...

  19. 43 CFR 10010.10 - Whether to prepare an EIS.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... actions would have no significant effect on the quality of the human environment; and (ii) The action or... addressed in subpart C of this part. (c) Finding of No Significant Impact (FONSI) (40 CFR 1508.13). A FONSI... proposed action will have no significant environmental impact. (d) Notice of Intent (NOI) (40 CFR 1508.22...

  20. 7 CFR 1940.329 - Commenting on other Agencies' EIS's.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... should be clearly identified. Special attention should be given to the relationship of the alternatives under study to the State Office's natural resource management guide and the objectives of the...

  1. 7 CFR 1794.25 - Proposals normally requiring an EIS.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... (nameplate rating) other than fuel cell, combustion turbine, combined cycle, or diesel generators. All new... water and waste programs. No groups or sets of proposed actions normally require the preparation of...

  2. 7 CFR 650.7 - When to prepare an EIS.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE... realignment or work to modify channel capacity by deepening or widening where significant aquatic or wildlife... environment (§ 650.7(e)); and (4) Other major Federal actions that are determined after...

  3. 7 CFR 650.7 - When to prepare an EIS.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE... realignment or work to modify channel capacity by deepening or widening where significant aquatic or wildlife... environment (§ 650.7(e)); and (4) Other major Federal actions that are determined after...

  4. 7 CFR 650.7 - When to prepare an EIS.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE... realignment or work to modify channel capacity by deepening or widening where significant aquatic or wildlife... environment (§ 650.7(e)); and (4) Other major Federal actions that are determined after...

  5. 7 CFR 650.7 - When to prepare an EIS.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE... realignment or work to modify channel capacity by deepening or widening where significant aquatic or wildlife... environment (§ 650.7(e)); and (4) Other major Federal actions that are determined after...

  6. 32 CFR 651.42 - Actions normally requiring an EIS.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... effect on wetlands, coastal zones, or other areas of critical environmental concern. (c) The disposal of... substances that have the potential to cause significant environmental impact. (d) Land acquisition,...

  7. Astrometric Measurements of WDS 15482+0134 EIS 1AB

    NASA Astrophysics Data System (ADS)

    Kraver, Cassandra; Van Steenwyk, Charles; Ryan, Charles; Forrest, Nancy; Irving, Jenae; Krueger, Aaron; Genet, Russell; Johnson, Jo; Clifford, Matthew

    2017-04-01

    Ten separations and position angles were obtained of WDS 15482+0134 AB with the CDK-700 telescope in the iTelescope array. The mean values of these measurements were compared to historical observations. Although there was a discrepancy between our separations and the historical data, the position angle matched quite well.

  8. Geothermal NEPA Database on OpenEI (Poster)

    SciTech Connect

    Young, K. R.; Levine, A.

    2014-09-01

    The National Renewable Energy Laboratory (NREL) developed the Geothermal National Environmental Policy Act (NEPA) Database as a platform for government agencies and industry to access and maintain information related to geothermal NEPA documents. The data were collected to inform analyses of NEPA timelines, and the collected data were made publically available via this tool in case others might find the data useful. NREL staff and contractors collected documents from agency websites, during visits to the two busiest Bureau of Land Management (BLM) field offices for geothermal development, and through email and phone call requests from other BLM field offices. They then entered the information into the database, hosted by Open Energy Information (http://en.openei.org/wiki/RAPID/NEPA). The long-term success of the project will depend on the willingness of federal agencies, industry, and others to populate the database with NEPA and related documents, and to use the data for their own analyses. As the information and capabilities of the database expand, developers and agencies can save time on new NEPA reports by accessing a single location to research related activities, their potential impacts, and previously proposed and imposed mitigation measures. NREL used a wiki platform to allow industry and agencies to maintain the content in the future so that it continues to provide relevant and accurate information to users.

  9. 32 CFR 651.41 - Conditions requiring an EIS.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) ENVIRONMENTAL QUALITY ENVIRONMENTAL ANALYSIS OF ARMY ACTIONS (AR 200-2) Environmental Impact Statement § 651.41... environmental effects result. (h) Involve the production, storage, transportation, use, treatment, and disposal of hazardous or toxic materials that may have significant environmental impact. (i) Be highly...

  10. 7 CFR 1794.25 - Proposals normally requiring an EIS.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... (nameplate rating) other than fuel cell, combustion turbine, combined cycle, or diesel generators. All new... water and waste programs. No groups or sets of proposed actions normally require the preparation of...

  11. 7 CFR 1794.25 - Proposals normally requiring an EIS.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... (nameplate rating) other than fuel cell, combustion turbine, combined cycle, or diesel generators. All new... water and waste programs. No groups or sets of proposed actions normally require the preparation of...

  12. Supplement Analysis for the Watershed Management Program EIS (DOE/EIS-0265/SA-75) - Gourlay Creek Fish Ladder Project

    SciTech Connect

    Stewart, Shannon C.

    2002-02-20

    BPA proposes to fund the construction of a fish passage facility at the Gourlay Creek Dam/water reservoir in Columbia County, Oregon. The City of Scappoose owns and manages close to half of the Gourlay Creek Watershed including high quality habitat above and below the Gourlay Creek Dam. Gourlay Creek Dam has been identified as a key limiting factor in the re-generation of salmon and trout in the Gourlay Creek Watershed. Currently it provides a complete barrier to fish passage for Endangered Species Act (ESA) listed salmonids, as well as to salmonids that are under status review for ESA listing. Historically, Gourlay Creek has provided important salmonid habitat within the Scappoose Bay Watershed. Salmonids still utilize the lower reaches of Gourlay Creek. The goal of the project is to provide unimpeded access for juvenile and adult salmonids to historic habitat upstream of the dam. The project would open up over two miles of habitat for coho and cutthroat trout and nearly four miles of habitat for steelhead.

  13. Supplement Analysis for the Watershed Management Program EIS (DOE/EIS-0265/SA-155) - Blind Slough Restoration Project

    SciTech Connect

    Wittpenn, Nancy A.

    2004-07-09

    This project proposes to restore tidal connection between the Columbia River Estuary and Blind Slough through the replacement and/or installation of culverts, installation of water control devices, breaching of dikes, and channel enhancement. These enhancements would restore connectivity to approximately ten (10) miles of slough channels previously isolated from tidal influence due to dikes, road crossings, and constrained culverts.

  14. Supplement Analysis for the Wildlife Mitigation Program EIS (DOE/EIS-0246/SA-24) - Herbert Conservation Easement

    SciTech Connect

    Stewart, Shannon C.

    2002-05-23

    BPA proposes to purchase a conservation easement on approximately 221 acres of the Herbert parcel in Benton County, Oregon for the protection of wetland, riparian, and riverine habitats. The Herbert parcel is located within the Willamette Basin Mitigation Program’s Canby Muddy Creek/Mary’s River Focus Area southwest of the City of Corvallis. The Herbert site is a cooperative project principally facilitated by BPA, Trust for Public Land, City of Corvallis, and Oregon Department of Fish and Wildlife. Once the conservation easement is finalized, the participants will develop a management plan for the Herbert parcel. Future management actions will likely involve the restoration and enhancement of riparian forests, wetlands, and riverine habitats. This Supplement Analysis covers the acquisition of the Herbert conservation easement only; all proposed management activities will require additional NEPA analysis prior to implementation.

  15. Supplement Analysis for the Wildlife Mitigation Program EIS (DOE/EIS-0246/SA-23) - Canby Ferry Conservation Easement

    SciTech Connect

    Stewart, Shannon C.

    2002-05-15

    BPA proposes to purchase a conservation easement on approximately 16 acres of the Canby Ferry parcel in Clackamas County, Oregon for the protection of wetland, riparian, and riverine habitats. This project is part of a multi-agency effort to protect Willamette River frontage and to connect existing Oregon State Park lands with recreational trails. Once the conservation easement is finalized, a management plan will be developed for the Canby Ferry parcel and adjacent parcels, including the Fish Eddy parcel and the Molalla State Park parcel. Future management actions on these lands will likely involve wildlife habitat and riparian area enhancement, restoration, and preservation activities. This Supplement Analysis covers the acquisition of the Canby Ferry conservation easement only; all proposed management activities (on the Canby Ferry parcel and adjacent parcels) will require additional NEPA analysis prior to implementation.

  16. Supplement Analysis for the Watershed Management Program EIS (DOE/EIS-0265/SA-63) - Pelican Creek Crossing Improvement

    SciTech Connect

    Stewart, Shannon C.

    2001-09-17

    BPA provides funds to the Grande Ronde Model Watershed Program which cooperates with local agencies and landowners to plan, fund, and implement anadromous fish habitat restoration projects in the Grande Ronde Basin. The GRMWP has agreed to partially fund three bridge replacement projects with the Union County Public Works Department. This Supplement Analysis covers only the bridge replacement activities that will take place at the Pelican Creek crossing. The Union County Public Works Department is responsible for replacing structurally deficient bridges with structures able to pass 50-year peak flow events. The UCPWD replacement structures of choice, due to budget limitations, are large 8-10 foot corrugated metal pipes. These pipes would meet peak flow requirements but would be less than ideal for fish passage. The GRMWP proposes to provide funding assistance to UCPWD to upgrade replacement structures to full-channel spanning stringer bridges. These full-channel spanning structures will provide the best possible conditions for fish passage, water quality, and accommodation of peak flows.

  17. Supplement Analysis for the Watershed Management Program EIS (DOE/EIS-0265/SA-79) - Eisminger/ CREP Dike Relocation

    SciTech Connect

    Stewart, Shannon C.

    2002-05-20

    BPA proposes to partially fund a project with the Union County Soil and Water Conservation District that will relocate 4,500 feet of existing dike along the Grande Ronde River, re-create native wetlands, relocate an existing powerline, and establish a riparian forest buffer. These actions are part of a Conservation Reserve Enhancement Program (CREP) project. The project is cooperatively funded by the Natural Resource Conservation Service, Farm Service Agency, Oregon Department of Forestry, BPA, and the landowner. BPA funds will be used to move an existing powerline. The goal of the proposed project is to: protect valuable cropland from flooding; improve floodplain function by allowing the river better access to the floodplain during periods of high water; improve riparian and floodplain sediment filtering capacity; improve riparian quality and function; and restore wetlands.

  18. Supplement Analysis for the Watershed Management Program EIS (DOE/EIS-0265/SA-95) - Libby Creek Channel Stabilization Project

    SciTech Connect

    Keller, Carl J.

    2002-10-21

    BPA proposes to fund MFWP to construct a channel stabilization project, which would restore the dimension, pattern, and profile of 3,200 feet of Libby Creek. The project calls for shaping cut banks to a 2:1 slope, installing root wads and tree revetments; and planting and restoring native grasses and riparian shrubs along the margin of the channel. Cross vanes (constructed from rock) and trees will also be established to control channel gradient within the project area. This project is one restoration phase on Libby Creek, and was identified as important by the Libby Area Conservation District, MFWP, U.S. Forest Service, and U.S. Army Corps of Engineers. Libby Creek is also the focus of restoration efforts based, in part, on the finding of the Montana Governor’s Bull Trout Restoration Technical Committee. This Committee identified Libby Creek as critical spawning and migratory habitat for the threatened bull trout. This project reach of Libby Creek is also rearing habitat for resident redband trout and resident and fluvial bull trout migrating from the Kootenai River.

  19. Supplement Analysis for the Watershed Management Program EIS (DOE/EIS-0265/SA-71) - Duncan Creek Channel Rehabilitation Project

    SciTech Connect

    Stewart, Shannon C.

    2001-10-29

    BPA proposes to fund a project with the Washington State Department of Fish and Wildlife that will restore historic spawning areas for chum salmon in Duncan Creek. Duncan Creek, a Washington tributary of the Columbia River, was traditionally an important spawning area for chum salmon. The spring seeps areas that chum historically used for spawning are still present in Duncan Creek, however during the past 30 years they have been covered by sediment and debris and infested with reed canary grass. This project proposes to rehabilitate these spawning channels in order to provide chum salmon with a protected spawning and incubation environment. The proposed habitat rehabilitation project will include removing existing gravel in the seeps of Duncan Creek that contain mud, sand, and organics and replacing them with gravels that will maximize egg-to-fry survival rates for chum salmon. A trackhoe or similar equipment will be used to excavate the spawning sites. Invasive vegetation will be removed. Spawning channels will then be reconstructed using sediment free spawning gravels and base rock. Upon completion of work, all disturbed spring channel banks will be protected from erosion with staked coir fabric and revegetated with native willows. Plantings will help to restore native plant communities, increase stream channel shading, and reduce re-infestation by reed canary grass.

  20. Supplement Analysis for the Watershed Management Program EIS (DOE/EIS-0265/SA-105) - Water Entity (Washington Water Trust 2003)

    SciTech Connect

    Yarde, Richard

    2003-06-13

    BPA proposes to fund several water rights acquisition projects proposed by the Washington Water Trust (WWT). The funding will be administered by the National Fish and Wildlife Foundation, the entity administering the Columbia Basin Water Transactions Program, initiated under RPA 151 of the National Marine Fisheries Service’s 2000 Biological Opinion on the Operation of the Federal Columbia River Power System. The water rights acquired by the WWT will be left instream to increase flow and improve water quality. Increasing instream flow of water-limited streams benefits fish listed under the Endangered Species Act. The three projects proposed by the WWT include: renewing a lease for 0.43 cubic feet per second (cfs) in the Methow River for three years; renewing a lease of 1.29 cfs to be protected in a 0.75 mile stretch of Gold Creek, a tributary to the Methow River, for one year; and renewing a lease of 0.17 cfs in a 0.2 mi stretch of Frazer Creek, a tributary of the Methow River, for two years.