Widening the Knowledge Acquisition Bottleneck for Constraint-Based Tutors
ERIC Educational Resources Information Center
Suraweera, Pramuditha; Mitrovic, Antonija; Martin, Brent
2010-01-01
Intelligent Tutoring Systems (ITS) are effective tools for education. However, developing them is a labour-intensive and time-consuming process. A major share of the effort is devoted to acquiring the domain knowledge that underlies the system's intelligence. The goal of this research is to reduce this knowledge acquisition bottleneck and better…
Combining factual and heuristic knowledge in knowledge acquisition
NASA Technical Reports Server (NTRS)
Gomez, Fernando; Hull, Richard; Karr, Clark; Hosken, Bruce; Verhagen, William
1992-01-01
A knowledge acquisition technique that combines heuristic and factual knowledge represented as two hierarchies is described. These ideas were applied to the construction of a knowledge acquisition interface to the Expert System Analyst (OPERA). The goal of OPERA is to improve the operations support of the computer network in the space shuttle launch processing system. The knowledge acquisition bottleneck lies in gathering knowledge from human experts and transferring it to OPERA. OPERA's knowledge acquisition problem is approached as a classification problem-solving task, combining this approach with the use of factual knowledge about the domain. The interface was implemented in a Symbolics workstation making heavy use of windows, pull-down menus, and other user-friendly devices.
Autonomously acquiring declarative and procedural knowledge for ICAT systems
NASA Technical Reports Server (NTRS)
Kovarik, Vincent J., Jr.
1993-01-01
The construction of Intelligent Computer Aided Training (ICAT) systems is critically dependent on the ability to define and encode knowledge. This knowledge engineering effort can be broadly divided into two categories: domain knowledge and expert or task knowledge. Domain knowledge refers to the physical environment or system with which the expert interacts. Expert knowledge consists of the set of procedures and heuristics employed by the expert in performing their task. Both these areas are a significant bottleneck in the acquisition of knowledge for ICAT systems. This paper presents a research project in the area of autonomous knowledge acquisition using a passive observation concept. The system observes an expert and then generalizes the observations into production rules representing the domain expert's knowledge.
Back of the Envelope Reasoning for Robust Quantitative Problem Solving
2007-12-31
limited numeric vocabulary, for example, the Pirahã tribe in Amazonia [Gordon, 2004] and Munduruku [Pica et al., 2004], an Amazonian language... investigation of category structure: 1. Level of categorization: Rosch [1978] identifies three levels of categorization: subordinate, basic-level...Using Common Sense Knowledge to Overcome Brittleness and Knowledge Acquisition Bottlenecks. AI Magazine . Lenhart K. Schubert and Matthew Tong
Machine Learning. Part 1. A Historical and Methodological Analysis.
1983-05-31
Machine learning has always been an integral part of artificial intelligence, and its methodology has evolved in concert with the major concerns of the field. In response to the difficulties of encoding ever-increasing volumes of knowledge in modern Al systems, many researchers have recently turned their attention to machine learning as a means to overcome the knowledge acquisition bottleneck. Part 1 of this paper presents a taxonomic analysis of machine learning organized primarily by learning strategies and secondarily by
Management of Knowledge Representation Standards Activities
NASA Technical Reports Server (NTRS)
Patil, Ramesh S.
1993-01-01
Ever since the mid-seventies, researchers have recognized that capturing knowledge is the key to building large and powerful AI systems. In the years since, we have also found that representing knowledge is difficult and time consuming. In spite of the tools developed to help with knowledge acquisition, knowledge base construction remains one of the major costs in building an Al system: For almost every system we build, a new knowledge base must be constructed from scratch. As a result, most systems remain small to medium in size. Even if we build several systems within a general area, such as medicine or electronics diagnosis, significant portions of the domain must be represented for every system we create. The cost of this duplication of effort has been high and will become prohibitive as we attempt to build larger and larger systems. To overcome this barrier we must find ways of preserving existing knowledge bases and of sharing, re-using, and building on them. This report describes the efforts undertaken over the last two years to identify the issues underlying the current difficulties in sharing and reuse, and a community wide initiative to overcome them. First, we discuss four bottlenecks to sharing and reuse, present a vision of a future in which these bottlenecks have been ameliorated, and describe the efforts of the initiative's four working groups to address these bottlenecks. We then address the supporting technology and infrastructure that is critical to enabling the vision of the future. Finally, we consider topics of longer-range interest by reviewing some of the research issues raised by our vision.
Graph-based real-time fault diagnostics
NASA Technical Reports Server (NTRS)
Padalkar, S.; Karsai, G.; Sztipanovits, J.
1988-01-01
A real-time fault detection and diagnosis capability is absolutely crucial in the design of large-scale space systems. Some of the existing AI-based fault diagnostic techniques like expert systems and qualitative modelling are frequently ill-suited for this purpose. Expert systems are often inadequately structured, difficult to validate and suffer from knowledge acquisition bottlenecks. Qualitative modelling techniques sometimes generate a large number of failure source alternatives, thus hampering speedy diagnosis. In this paper we present a graph-based technique which is well suited for real-time fault diagnosis, structured knowledge representation and acquisition and testing and validation. A Hierarchical Fault Model of the system to be diagnosed is developed. At each level of hierarchy, there exist fault propagation digraphs denoting causal relations between failure modes of subsystems. The edges of such a digraph are weighted with fault propagation time intervals. Efficient and restartable graph algorithms are used for on-line speedy identification of failure source components.
Psychological tools for knowledge acquisition
NASA Technical Reports Server (NTRS)
Rueter, Henry H.; Olson, Judith Reitman
1988-01-01
Knowledge acquisition is said to be the biggest bottleneck in the development of expert systems. The problem is getting the knowledge out of the expert's head and into a computer. In cognitive psychology, characterizing metal structures and why experts are good at what they do is an important research area. Is there some way that the tools that psychologists have developed to uncover mental structure can be used to benefit knowledge engineers? We think that the way to find out is to browse through the psychologist's toolbox to see what there is in it that might be of use to knowledge engineers. Expert system developers have relied on two standard methods for extracting knowledge from the expert: (1) the knowledge engineer engages in an intense bout of interviews with the expert or experts, or (2) the knowledge engineer becomes an expert himself, relying on introspection to uncover the basis of his own expertise. Unfortunately, these techniques have the difficulty that often the expert himself isn't consciously aware of the basis of his expertise. If the expert himself isn't conscious of how he solves problems, introspection is useless. Cognitive psychology has faced similar problems for many years and has developed exploratory methods that can be used to discover cognitive structure from simple data.
Chater, Nick; Christiansen, Morten H
2016-01-01
If human language must be squeezed through a narrow cognitive bottleneck, what are the implications for language processing, acquisition, change, and structure? In our target article, we suggested that the implications are far-reaching and form the basis of an integrated account of many apparently unconnected aspects of language and language processing, as well as suggesting revision of many existing theoretical accounts. With some exceptions, commentators were generally supportive both of the existence of the bottleneck and its potential implications. Many commentators suggested additional theoretical and linguistic nuances and extensions, links with prior work, and relevant computational and neuroscientific considerations; some argued for related but distinct viewpoints; a few, though, felt traditional perspectives were being abandoned too readily. Our response attempts to build on the many suggestions raised by the commentators and to engage constructively with challenges to our approach.
Bottleneck Analysis on the DoD Pre-Milestone B Acquisition Processes
2013-04-01
Acquisition Processes Danielle Worger and Teresa Wu, Arizona State University Eugene Rex Jalao, Arizona State University and University of the...Danielle Worger and Teresa Wu, Arizona State University Eugene Rex Jalao, Arizona State University and University of the Philippines Christopher...Air Force Institute of Technology The RITE Approach to Agile Acquisition Timothy Boyce, Iva Sherman, and Nicholas Roussel Space and Naval Warfare
Linguistics, cognitive psychology, and the Now-or-Never bottleneck.
Endress, Ansgar D; Katzir, Roni
2016-01-01
Christiansen & Chater (C&C)'s key premise is that "if linguistic information is not processed rapidly, that information is lost for good" (sect. 1, para. 1). From this "Now-or-Never bottleneck" (NNB), C&C derive "wide-reaching and fundamental implications for language processing, acquisition and change as well as for the structure of language itself" (sect. 2, para. 10). We question both the premise and the consequentiality of its purported implications.
NASA Technical Reports Server (NTRS)
Allen, Bradley P.; Holtzman, Peter L.
1987-01-01
An overview is presented of the Automated Software Development Workstation Project, an effort to explore knowledge-based approaches to increasing software productivity. The project focuses on applying the concept of domain specific automatic programming systems (D-SAPSs) to application domains at NASA's Johnson Space Center. A version of a D-SAPS developed in Phase 1 of the project for the domain of space station momentum management is described. How problems encountered during its implementation led researchers to concentrate on simplifying the process of building and extending such systems is discussed. Researchers propose to do this by attacking three observed bottlenecks in the D-SAPS development process through the increased automation of the acquisition of programming knowledge and the use of an object oriented development methodology at all stages of the program design. How these ideas are being implemented in the Bauhaus, a prototype workstation for D-SAPS development is discussed.
NASA Technical Reports Server (NTRS)
Allen, Bradley P.; Holtzman, Peter L.
1988-01-01
An overview is presented of the Automated Software Development Workstation Project, an effort to explore knowledge-based approaches to increasing software productivity. The project focuses on applying the concept of domain specific automatic programming systems (D-SAPSs) to application domains at NASA's Johnson Space Flight Center. A version of a D-SAPS developed in Phase 1 of the project for the domain of space station momentum management is described. How problems encountered during its implementation led researchers to concentrate on simplifying the process of building and extending such systems is discussed. Researchers propose to do this by attacking three observed bottlenecks in the D-SAPS development process through the increased automation of the acquisition of programming knowledge and the use of an object oriented development methodology at all stages of the program design. How these ideas are being implemented in the Bauhaus, a prototype workstation for D-SAPS development is discussed.
Evolutionary Intelligence and Communication in Societies of Virtually Embodied Agents
NASA Astrophysics Data System (ADS)
Nguyen, Binh; Skabar, Andrew
In order to overcome the knowledge bottleneck problem, AI researchers have attempted to develop systems that are capable of automated knowledge acquisition. However, learning in these systems is hindered by context (i.e., symbol-grounding) problems, which are caused by the systems lacking the unifying structure of bodies, situations and needs that typify human learning. While the fields of Embodied Artificial Intelligence and Artificial Life have come a long way towards demonstrating how artificial systems can develop knowledge of the physical and social worlds, the focus in these areas has been on low level intelligence, and it is not clear how, such systems can be extended to deal with higher-level knowledge. In this paper, we argue that we can build towards a higher level intelligence by framing the problem as one of stimulating the development of culture and language. Specifically, we identify three important limitations that face the development of culture and language in AI systems, and propose how these limitations can be overcome. We will do this through borrowing ideas from the evolutionary sciences, which have explored how interactions between embodiment and environment have shaped the development of human intelligence and knowledge.
Overcoming gaps and bottlenecks to advance precision agriculture
USDA-ARS?s Scientific Manuscript database
Maintaining a clear understanding of the technology gaps, knowledge needs, and training bottlenecks is required for improving adoption of precision agriculture. As an industry, precision agriculture embraces tools, methods, and practices that are constantly changing, requiring industry, education, a...
NASA Astrophysics Data System (ADS)
Krawczyk, Rafał D.; Czarski, Tomasz; Kolasiński, Piotr; Linczuk, Paweł; Poźniak, Krzysztof T.; Chernyshova, Maryna; Kasprowicz, Grzegorz; Wojeński, Andrzej; Zabolotny, Wojciech; Zienkiewicz, Paweł
2016-09-01
This article is an overview of what has been implemented in the process of development and testing the GEM detector based acquisition system in terms of post-processing algorithms. Information is given on mex functions for extended statistics collection, unified hex topology and optimized S-DAQ algorithm for splitting overlapped signals. Additional discussion on bottlenecks and major factors concerning optimization is presented.
Lexical Link Analysis Application: Improving Web Service to Acquisition Visibility Portal
2013-04-01
Maryland Bottleneck Analysis on the DoD Pre-Milestone B Acquisition Processes Danielle Worger and Teresa Wu, Arizona State University Eugene Rex ...Creative Program Management Best Practices Brandon Keller and J. Robert Wirthlin Air Force Institute of Technology The RITE Approach to Agile ...Mechanism for Adaptive Change Kathryn Aten and John T . Dillard Naval Postgraduate School A Comparative Assessment of the Navy’s Future Naval
NASA Technical Reports Server (NTRS)
Bailin, Sydney; Paterra, Frank; Henderson, Scott; Truszkowski, Walt
1993-01-01
This paper presents a discussion of current work in the area of graphical modeling and model-based reasoning being undertaken by the Automation Technology Section, Code 522.3, at Goddard. The work was initially motivated by the growing realization that the knowledge acquisition process was a major bottleneck in the generation of fault detection, isolation, and repair (FDIR) systems for application in automated Mission Operations. As with most research activities this work started out with a simple objective: to develop a proof-of-concept system demonstrating that a draft rule-base for a FDIR system could be automatically realized by reasoning from a graphical representation of the system to be monitored. This work was called Knowledge From Pictures (KFP) (Truszkowski et. al. 1992). As the work has successfully progressed the KFP tool has become an environment populated by a set of tools that support a more comprehensive approach to model-based reasoning. This paper continues by giving an overview of the graphical modeling objectives of the work, describing the three tools that now populate the KFP environment, briefly presenting a discussion of related work in the field, and by indicating future directions for the KFP environment.
ERIC Educational Resources Information Center
Melkote, Srinivas R.; Babbili, Anantha S.
The paradox of the diffusion of innovations research is that in its efforts to find ways and means of breaking the communication constraint in Third World countries, it has generated many bottlenecks that cumulatively constitute the major constraint: lack of an efficient system for delivering adequate and reliable information, knowledge, and…
The Now-or-Never bottleneck: A fundamental constraint on language.
Christiansen, Morten H; Chater, Nick
2016-01-01
Memory is fleeting. New material rapidly obliterates previous material. How, then, can the brain deal successfully with the continual deluge of linguistic input? We argue that, to deal with this "Now-or-Never" bottleneck, the brain must compress and recode linguistic input as rapidly as possible. This observation has strong implications for the nature of language processing: (1) the language system must "eagerly" recode and compress linguistic input; (2) as the bottleneck recurs at each new representational level, the language system must build a multilevel linguistic representation; and (3) the language system must deploy all available information predictively to ensure that local linguistic ambiguities are dealt with "Right-First-Time"; once the original input is lost, there is no way for the language system to recover. This is "Chunk-and-Pass" processing. Similarly, language learning must also occur in the here and now, which implies that language acquisition is learning to process, rather than inducing, a grammar. Moreover, this perspective provides a cognitive foundation for grammaticalization and other aspects of language change. Chunk-and-Pass processing also helps explain a variety of core properties of language, including its multilevel representational structure and duality of patterning. This approach promises to create a direct relationship between psycholinguistics and linguistic theory. More generally, we outline a framework within which to integrate often disconnected inquiries into language processing, language acquisition, and language change and evolution.
Castro, Alexander Garcia; Rocca-Serra, Philippe; Stevens, Robert; Taylor, Chris; Nashar, Karim; Ragan, Mark A; Sansone, Susanna-Assunta
2006-01-01
Background Incorporation of ontologies into annotations has enabled 'semantic integration' of complex data, making explicit the knowledge within a certain field. One of the major bottlenecks in developing bio-ontologies is the lack of a unified methodology. Different methodologies have been proposed for different scenarios, but there is no agreed-upon standard methodology for building ontologies. The involvement of geographically distributed domain experts, the need for domain experts to lead the design process, the application of the ontologies and the life cycles of bio-ontologies are amongst the features not considered by previously proposed methodologies. Results Here, we present a methodology for developing ontologies within the biological domain. We describe our scenario, competency questions, results and milestones for each methodological stage. We introduce the use of concept maps during knowledge acquisition phases as a feasible transition between domain expert and knowledge engineer. Conclusion The contributions of this paper are the thorough description of the steps we suggest when building an ontology, example use of concept maps, consideration of applicability to the development of lower-level ontologies and application to decentralised environments. We have found that within our scenario conceptual maps played an important role in the development process. PMID:16725019
Management of Knowledge Representation Standards Activities
NASA Technical Reports Server (NTRS)
Patil, Ramesh S. (Principal Investigator)
1993-01-01
This report describes the efforts undertaken over the last two years to identify the issues underlying the current difficulties in sharing and reuse, and a community wide initiative to overcome them. First, we discuss four bottlenecks to sharing and reuse, present a vision of a future in which these bottlenecks have been ameliorated, and describe the efforts of the initiative's four working groups to address these bottlenecks. We then address the supporting technology and infrastructure that is critical to enabling the vision of the future. Finally, we consider topics of longer-range interest by reviewing some of the research issues raised by our vision.
Language processing is not a race against time.
Baggio, Giosuè; Vicario, Carmelo M
2016-01-01
We agree with Christiansen & Chater (C&C) that language processing and acquisition are tightly constrained by the limits of sensory and memory systems. However, the human brain supports a range of cognitive functions that mitigate the effects of information processing bottlenecks. The language system is partly organised around these moderating factors, not just around restrictions on storage and computation.
Semantic relatedness for evaluation of course equivalencies
NASA Astrophysics Data System (ADS)
Yang, Beibei
Semantic relatedness, or its inverse, semantic distance, measures the degree of closeness between two pieces of text determined by their meaning. Related work typically measures semantics based on a sparse knowledge base such as WordNet or Cyc that requires intensive manual efforts to build and maintain. Other work is based on a corpus such as the Brown corpus, or more recently, Wikipedia. This dissertation proposes two approaches to applying semantic relatedness to the problem of suggesting transfer course equivalencies. Two course descriptions are given as input to feed the proposed algorithms, which output a value that can be used to help determine if the courses are equivalent. The first proposed approach uses traditional knowledge sources such as WordNet and corpora for courses from multiple fields of study. The second approach uses Wikipedia, the openly-editable encyclopedia, and it focuses on courses from a technical field such as Computer Science. This work shows that it is promising to adapt semantic relatedness to the education field for matching equivalencies between transfer courses. A semantic relatedness measure using traditional knowledge sources such as WordNet performs relatively well on non-technical courses. However, due to the "knowledge acquisition bottleneck," such a resource is not ideal for technical courses, which use an extensive and growing set of technical terms. To address the problem, this work proposes a Wikipedia-based approach which is later shown to be more correlated to human judgment compared to previous work.
Lozano-Diez, Alicia; Zazo, Ruben; Toledano, Doroteo T; Gonzalez-Rodriguez, Joaquin
2017-01-01
Language recognition systems based on bottleneck features have recently become the state-of-the-art in this research field, showing its success in the last Language Recognition Evaluation (LRE 2015) organized by NIST (U.S. National Institute of Standards and Technology). This type of system is based on a deep neural network (DNN) trained to discriminate between phonetic units, i.e. trained for the task of automatic speech recognition (ASR). This DNN aims to compress information in one of its layers, known as bottleneck (BN) layer, which is used to obtain a new frame representation of the audio signal. This representation has been proven to be useful for the task of language identification (LID). Thus, bottleneck features are used as input to the language recognition system, instead of a classical parameterization of the signal based on cepstral feature vectors such as MFCCs (Mel Frequency Cepstral Coefficients). Despite the success of this approach in language recognition, there is a lack of studies analyzing in a systematic way how the topology of the DNN influences the performance of bottleneck feature-based language recognition systems. In this work, we try to fill-in this gap, analyzing language recognition results with different topologies for the DNN used to extract the bottleneck features, comparing them and against a reference system based on a more classical cepstral representation of the input signal with a total variability model. This way, we obtain useful knowledge about how the DNN configuration influences bottleneck feature-based language recognition systems performance.
Capturing Creative Program Management Best Practices
2013-04-01
Maryland Bottleneck Analysis on the DoD Pre-Milestone B Acquisition Processes Danielle Worger and Teresa Wu, Arizona State University Eugene Rex Jalao...Creative Program Management Best Practices Brandon Keller and J. Robert Wirthlin Air Force Institute of Technology The RITE Approach to Agile ...Mechanism for Adaptive Change Kathryn Aten and John T . Dillard Naval Postgraduate School A Comparative Assessment of the Navy’s Future Naval Capabilities
Delic, Marizela; Göngrich, Rebecca; Mattanovich, Diethard; Gasser, Brigitte
2014-07-20
Recombinant protein production has developed into a huge market with enormous positive implications for human health and for the future direction of a biobased economy. Limitations in the economic and technical feasibility of production processes are often related to bottlenecks of in vivo protein folding. Based on cell biological knowledge, some major bottlenecks have been overcome by the overexpression of molecular chaperones and other folding related proteins, or by the deletion of deleterious pathways that may lead to misfolding, mistargeting, or degradation. While important success could be achieved by this strategy, the list of reported unsuccessful cases is disappointingly long and obviously dependent on the recombinant protein to be produced. Singular engineering of protein folding steps may not lead to desired results if the pathway suffers from several limitations. In particular, the connection between folding quality control and proteolytic degradation needs further attention. Based on recent understanding that multiple steps in the folding and secretion pathways limit productivity, synergistic combinations of the cell engineering approaches mentioned earlier need to be explored. In addition, systems biology-based whole cell analysis that also takes energy and redox metabolism into consideration will broaden the knowledge base for future rational engineering strategies.
Using fragmentation trees and mass spectral trees for identifying unknown compounds in metabolomics.
Vaniya, Arpana; Fiehn, Oliver
2015-06-01
Identification of unknown metabolites is the bottleneck in advancing metabolomics, leaving interpretation of metabolomics results ambiguous. The chemical diversity of metabolism is vast, making structure identification arduous and time consuming. Currently, comprehensive analysis of mass spectra in metabolomics is limited to library matching, but tandem mass spectral libraries are small compared to the large number of compounds found in the biosphere, including xenobiotics. Resolving this bottleneck requires richer data acquisition and better computational tools. Multi-stage mass spectrometry (MSn) trees show promise to aid in this regard. Fragmentation trees explore the fragmentation process, generate fragmentation rules and aid in sub-structure identification, while mass spectral trees delineate the dependencies in multi-stage MS of collision-induced dissociations. This review covers advancements over the past 10 years as a tool for metabolite identification, including algorithms, software and databases used to build and to implement fragmentation trees and mass spectral annotations.
DDS-Suite - A Dynamic Data Acquisition, Processing, and Analysis System for Wind Tunnel Testing
NASA Technical Reports Server (NTRS)
Burnside, Jathan J.
2012-01-01
Wind Tunnels have optimized their steady-state data systems for acquisition and analysis and even implemented large dynamic-data acquisition systems, however development of near real-time processing and analysis tools for dynamic-data have lagged. DDS-Suite is a set of tools used to acquire, process, and analyze large amounts of dynamic data. Each phase of the testing process: acquisition, processing, and analysis are handled by separate components so that bottlenecks in one phase of the process do not affect the other, leading to a robust system. DDS-Suite is capable of acquiring 672 channels of dynamic data at rate of 275 MB / s. More than 300 channels of the system use 24-bit analog-to-digital cards and are capable of producing data with less than 0.01 of phase difference at 1 kHz. System architecture, design philosophy, and examples of use during NASA Constellation and Fundamental Aerodynamic tests are discussed.
Rapid Statistical Learning Supporting Word Extraction From Continuous Speech.
Batterink, Laura J
2017-07-01
The identification of words in continuous speech, known as speech segmentation, is a critical early step in language acquisition. This process is partially supported by statistical learning, the ability to extract patterns from the environment. Given that speech segmentation represents a potential bottleneck for language acquisition, patterns in speech may be extracted very rapidly, without extensive exposure. This hypothesis was examined by exposing participants to continuous speech streams composed of novel repeating nonsense words. Learning was measured on-line using a reaction time task. After merely one exposure to an embedded novel word, learners demonstrated significant learning effects, as revealed by faster responses to predictable than to unpredictable syllables. These results demonstrate that learners gained sensitivity to the statistical structure of unfamiliar speech on a very rapid timescale. This ability may play an essential role in early stages of language acquisition, allowing learners to rapidly identify word candidates and "break in" to an unfamiliar language.
[Structured residency training program for otolaryngology: a trendsetting principle].
Meyer, J E; Wollenberg, B; Schmidt, C
2008-09-01
A concept for an ORL residency training program is necessary because of personnel bottlenecks, quality assurance and benchmarkings. We have created a 2.5 years' program, which is based on 6 pillars: 1. Acquisition of the necessary specialist knowledge by the resident in self-study. 2. Weekly attendance of training lectures according to a study timetable, a monthly specialist seminar to discuss case examples. 3. Weekly presentation by the resident on an article from the current literature, alternating with a presentation on cases and a morbidity and mortality conference. 4. Annual 60 min learning target test. 5. Definition of a surgical training calendar oriented to the new national ORL training regulations. 6. Internal operation course with preparative exercises in anatomy and visit to an operations course at a renowned otolaryngology clinic each year. After 2.5 years of the training time a revision course is introduced. In this way a basic training will be guaranteed for all residents, which can be assessed by the annual test. Finally, the construction of a further training curriculum should lead to an improved transparent training, a higher standard of quality and improved staff satisfaction.
Data simulation for the Lightning Imaging Sensor (LIS)
NASA Technical Reports Server (NTRS)
Boeck, William L.
1991-01-01
This project aims to build a data analysis system that will utilize existing video tape scenes of lightning as viewed from space. The resultant data will be used for the design and development of the Lightning Imaging Sensor (LIS) software and algorithm analysis. The desire for statistically significant metrics implies that a large data set needs to be analyzed. Before 1990 the quality and quantity of video was insufficient to build a usable data set. At this point in time, there is usable data from missions STS-34, STS-32, STS-31, STS-41, STS-37, and STS-39. During the summer of 1990, a manual analysis system was developed to demonstrate that the video analysis is feasible and to identify techniques to deduce information that was not directly available. Because the closed circuit television system used on the space shuttle was intended for documentary TV, the current value of the camera focal length and pointing orientation, which are needed for photoanalysis, are not included in the system data. A large effort was needed to discover ancillary data sources as well as develop indirect methods to estimate the necessary parameters. Any data system coping with full motion video faces an enormous bottleneck produced by the large data production rate and the need to move and store the digitized images. The manual system bypassed the video digitizing bottleneck by using a genlock to superimpose pixel coordinates on full motion video. Because the data set had to be obtained point by point by a human operating a computer mouse, the data output rate was small. The loan and subsequent acquisition of a Abekas digital frame store with a real time digitizer moved the bottleneck from data acquisition to a problem of data transfer and storage. The semi-automated analysis procedure was developed using existing equipment and is described. A fully automated system is described in the hope that the components may come on the market at reasonable prices in the next few years.
EXPECT: Explicit Representations for Flexible Acquisition
NASA Technical Reports Server (NTRS)
Swartout, BIll; Gil, Yolanda
1995-01-01
To create more powerful knowledge acquisition systems, we not only need better acquisition tools, but we need to change the architecture of the knowledge based systems we create so that their structure will provide better support for acquisition. Current acquisition tools permit users to modify factual knowledge but they provide limited support for modifying problem solving knowledge. In this paper, the authors argue that this limitation (and others) stem from the use of incomplete models of problem-solving knowledge and inflexible specification of the interdependencies between problem-solving and factual knowledge. We describe the EXPECT architecture which addresses these problems by providing an explicit representation for problem-solving knowledge and intent. Using this more explicit representation, EXPECT can automatically derive the interdependencies between problem-solving and factual knowledge. By deriving these interdependencies from the structure of the knowledge-based system itself EXPECT supports more flexible and powerful knowledge acquisition.
Knowledge Acquisition Using Linguistic-Based Knowledge Analysis
Daniel L. Schmoldt
1998-01-01
Most knowledge-based system developmentefforts include acquiring knowledge from one or more sources. difficulties associated with this knowledge acquisition task are readily acknowledged by most researchers. While a variety of knowledge acquisition methods have been reported, little has been done to organize those different methods and to suggest how to apply them...
Friess, Daniel A.; Krauss, Ken W.; Horstman, Erik M.; Balke, Thorsten; Bouma, Tjeerd J.; Galli, Demis; Webb, Edward L.
2011-01-01
Intertidal wetlands such as saltmarshes and mangroves provide numerous important ecological functions, though they are in rapid and global decline. To better conserve and restore these wetland ecosystems, we need an understanding of the fundamental natural bottlenecks and thresholds to their establishment and long-term ecological maintenance. Despite inhabiting similar intertidal positions, the biological traits of these systems differ markedly in structure, phenology, life history, phylogeny and dispersal, suggesting large differences in biophysical interactions. By providing the first systematic comparison between saltmarshes and mangroves, we unravel how the interplay between species-specific life-history traits, biophysical interactions and biogeomorphological feedback processes determine where, when and what wetland can establish, the thresholds to long-term ecosystem stability, and constraints to genetic connectivity between intertidal wetland populations at the landscape level. To understand these process interactions, research into the constraints to wetland development, and biological adaptations to overcome these critical bottlenecks and thresholds requires a truly interdisciplinary approach.
Afshar, Yaser; Sbalzarini, Ivo F.
2016-01-01
Modern fluorescence microscopy modalities, such as light-sheet microscopy, are capable of acquiring large three-dimensional images at high data rate. This creates a bottleneck in computational processing and analysis of the acquired images, as the rate of acquisition outpaces the speed of processing. Moreover, images can be so large that they do not fit the main memory of a single computer. We address both issues by developing a distributed parallel algorithm for segmentation of large fluorescence microscopy images. The method is based on the versatile Discrete Region Competition algorithm, which has previously proven useful in microscopy image segmentation. The present distributed implementation decomposes the input image into smaller sub-images that are distributed across multiple computers. Using network communication, the computers orchestrate the collectively solving of the global segmentation problem. This not only enables segmentation of large images (we test images of up to 1010 pixels), but also accelerates segmentation to match the time scale of image acquisition. Such acquisition-rate image segmentation is a prerequisite for the smart microscopes of the future and enables online data compression and interactive experiments. PMID:27046144
Afshar, Yaser; Sbalzarini, Ivo F
2016-01-01
Modern fluorescence microscopy modalities, such as light-sheet microscopy, are capable of acquiring large three-dimensional images at high data rate. This creates a bottleneck in computational processing and analysis of the acquired images, as the rate of acquisition outpaces the speed of processing. Moreover, images can be so large that they do not fit the main memory of a single computer. We address both issues by developing a distributed parallel algorithm for segmentation of large fluorescence microscopy images. The method is based on the versatile Discrete Region Competition algorithm, which has previously proven useful in microscopy image segmentation. The present distributed implementation decomposes the input image into smaller sub-images that are distributed across multiple computers. Using network communication, the computers orchestrate the collectively solving of the global segmentation problem. This not only enables segmentation of large images (we test images of up to 10(10) pixels), but also accelerates segmentation to match the time scale of image acquisition. Such acquisition-rate image segmentation is a prerequisite for the smart microscopes of the future and enables online data compression and interactive experiments.
ERIC Educational Resources Information Center
Hoe, Siu Loon; McShane, Steven
2010-01-01
Purpose: The topic of organizational learning is populated with many theories and models; many relate to the enduring organizational learning framework consisting of knowledge acquisition, knowledge dissemination, and knowledge use. However, most of the research either emphasizes structural knowledge acquisition and dissemination as a composite…
Development of a knowledge acquisition tool for an expert system flight status monitor
NASA Technical Reports Server (NTRS)
Disbrow, J. D.; Duke, E. L.; Regenie, V. A.
1986-01-01
Two of the main issues in artificial intelligence today are knowledge acquisition dion and knowledge representation. The Dryden Flight Research Facility of NASA's Ames Research Center is presently involved in the design and implementation of an expert system flight status monitor that will provide expertise and knowledge to aid the flight systems engineer in monitoring today's advanced high-performance aircraft. The flight status monitor can be divided into two sections: the expert system itself and the knowledge acquisition tool. The knowledge acquisition tool, the means it uses to extract knowledge from the domain expert, and how that knowledge is represented for computer use is discussed. An actual aircraft system has been codified by this tool with great success. Future real-time use of the expert system has been facilitated by using the knowledge acquisition tool to easily generate a logically consistent and complete knowledge base.
Development of a knowledge acquisition tool for an expert system flight status monitor
NASA Technical Reports Server (NTRS)
Disbrow, J. D.; Duke, E. L.; Regenie, V. A.
1986-01-01
Two of the main issues in artificial intelligence today are knowledge acquisition and knowledge representation. The Dryden Flight Research Facility of NASA's Ames Research Center is presently involved in the design and implementation of an expert system flight status monitor that will provide expertise and knowledge to aid the flight systems engineer in monitoring today's advanced high-performance aircraft. The flight status monitor can be divided into two sections: the expert system itself and the knowledge acquisition tool. This paper discusses the knowledge acquisition tool, the means it uses to extract knowledge from the domain expert, and how that knowledge is represented for computer use. An actual aircraft system has been codified by this tool with great success. Future real-time use of the expert system has been facilitated by using the knowledge acquisition tool to easily generate a logically consistent and complete knowledge base.
From data to information and knowledge for geospatial applications
NASA Astrophysics Data System (ADS)
Schenk, T.; Csatho, B.; Yoon, T.
2006-12-01
An ever-increasing number of airborne and spaceborne data-acquisition missions with various sensors produce a glut of data. Sensory data rarely contains information in a explicit form such that an application can directly use it. The processing and analyzing of data constitutes a real bottleneck; therefore, automating the processes of gaining useful information and knowledge from the raw data is of paramount interest. This presentation is concerned with the transition from data to information and knowledge. With data we refer to the sensor output and we notice that data provide very rarely direct answers for applications. For example, a pixel in a digital image or a laser point from a LIDAR system (data) have no direct relationship with elevation changes of topographic surfaces or the velocity of a glacier (information, knowledge). We propose to employ the computer vision paradigm to extract information and knowledge as it pertains to a wide range of geoscience applications. After introducing the paradigm we describe the major steps to be undertaken for extracting information and knowledge from sensory input data. Features play an important role in this process. Thus we focus on extracting features and their perceptual organization to higher order constructs. We demonstrate these concepts with imaging data and laser point clouds. The second part of the presentation addresses the problem of combining data obtained by different sensors. An absolute prerequisite for successful fusion is to establish a common reference frame. We elaborate on the concept of sensor invariant features that allow the registration of such disparate data sets as aerial/satellite imagery, 3D laser point clouds, and multi/hyperspectral imagery. Fusion takes place on the data level (sensor registration) and on the information level. We show how fusion increases the degree of automation for reconstructing topographic surfaces. Moreover, fused information gained from the three sensors results in a more abstract surface representation with a rich set of explicit surface information that can be readily used by an analyst for applications such as change detection.
Acquisition of Simple and Complex Knowledge; A Knowledge Gap Perspective
ERIC Educational Resources Information Center
Le Heron, Judy; Sligo, Frank
2005-01-01
This paper assesses university students' acquisition of simple and complex knowledge, in exploring whether the knowledge gap hypothesis (KGH) with its origins in community-based research into people's informal learning from mass media, provides insights into students' acquisition and retention of information. The KGH posits that attempts to…
Knowledge Acquisition in Observational Astronomy.
ERIC Educational Resources Information Center
Vosniadou, Stella
This paper presents findings from research on knowledge acquisition in observational astronomy to demonstrate the kinds of intuitive models children form and to show how these models influence the acquisition of science knowledge. Sixty children of approximate ages 6, 9, and 12 were given a questionnaire to investigate their knowledge of the size,…
A framework for directional and higher-order reconstruction in photoacoustic tomography
NASA Astrophysics Data System (ADS)
Boink, Yoeri E.; Lagerwerf, Marinus J.; Steenbergen, Wiendelt; van Gils, Stephan A.; Manohar, Srirang; Brune, Christoph
2018-02-01
Photoacoustic tomography is a hybrid imaging technique that combines high optical tissue contrast with high ultrasound resolution. Direct reconstruction methods such as filtered back-projection, time reversal and least squares suffer from curved line artefacts and blurring, especially in the case of limited angles or strong noise. In recent years, there has been great interest in regularised iterative methods. These methods employ prior knowledge of the image to provide higher quality reconstructions. However, easy comparisons between regularisers and their properties are limited, since many tomography implementations heavily rely on the specific regulariser chosen. To overcome this bottleneck, we present a modular reconstruction framework for photoacoustic tomography, which enables easy comparisons between regularisers with different properties, e.g. nonlinear, higher-order or directional. We solve the underlying minimisation problem with an efficient first-order primal-dual algorithm. Convergence rates are optimised by choosing an operator-dependent preconditioning strategy. A variety of reconstruction methods are tested on challenging 2D synthetic and experimental data sets. They outperform direct reconstruction approaches for strong noise levels and limited angle measurements, offering immediate benefits in terms of acquisition time and quality. This work provides a basic platform for the investigation of future advanced regularisation methods in photoacoustic tomography.
USDA-ARS?s Scientific Manuscript database
The Tropical Andes is the most diverse of the recognized plant conservation hotspots. In contrast, there exists scant knowledge about patterns of genetic variation within its constituent species. Understanding genetic variation is essential to develop successful conservation plans. Phaedranassa tun...
ERIC Educational Resources Information Center
Pearl, Lisa; Ho, Timothy; Detrano, Zephyr
2017-01-01
It has long been recognized that there is a natural dependence between theories of knowledge representation and theories of knowledge acquisition, with the idea that the right knowledge representation enables acquisition to happen as reliably as it does. Given this, a reasonable criterion for a theory of knowledge representation is that it be…
On the acquisition and representation of procedural knowledge
NASA Technical Reports Server (NTRS)
Saito, T.; Ortiz, C.; Loftin, R. B.
1992-01-01
Historically knowledge acquisition has proven to be one of the greatest barriers to the development of intelligent systems. Current practice generally requires lengthy interactions between the expert whose knowledge is to be captured and the knowledge engineer whose responsibility is to acquire and represent knowledge in a useful form. Although much research has been devoted to the development of methodologies and computer software to aid in the capture and representation of some of some types of knowledge, little attention has been devoted to procedural knowledge. NASA personnel frequently perform tasks that are primarily procedural in nature. Previous work is reviewed in the field of knowledge acquisition and then focus on knowledge acquisition for procedural tasks with special attention devoted to the Navy's VISTA tool. The design and development is described of a system for the acquisition and representation of procedural knowledge-TARGET (Task Analysis and Rule Generation Tool). TARGET is intended as a tool that permits experts to visually describe procedural tasks and as a common medium for knowledge refinement by the expert and knowledge engineer. The system is designed to represent the acquired knowledge in the form of production rules. Systems such as TARGET have the potential to profoundly reduce the time, difficulties, and costs of developing knowledge-based systems for the performance of procedural tasks.
Soper, Tracey
2017-04-01
The aim of this quantitative experimental study was to examine which of three instructional methodologies of traditional lecture, online electronic learning (e-learning) and self-study take-home packets are effective in knowledge acquisition of professional registered nurses. A true experimental design was conducted to contrast the knowledge acquisition of 87 registered nurses randomly selected. A 40-item Acute Coronary Syndrome (ACS) true/false test was used to measure knowledge acquisition. Based on 0.05 significance level, the ANOVA test revealed that there was no difference in knowledge acquisition by registered nurses based on which of three learning instructional method they were assigned. It can be concluded that while all of these instructional methods were equally effective in knowledge acquisition, these methods may not be equally cost- and time-effective. The study was able to determine that there were no significant differences in knowledge acquisition of nurses between the three instructional methodologies. The study also found that all groups scored at the acceptable level for certification. It can be concluded that all of these instructional methods were equally effective in knowledge acquisition but are not equally cost- and time-effective. Therefore, hospital educators may wish to formulate policies regarding choice of instructional method that take into account the efficient use of nurses' time and institutional resources.
Effects of Prior Knowledge on Memory: Implications for Education
ERIC Educational Resources Information Center
Shing, Yee Lee; Brod, Garvin
2016-01-01
The encoding, consolidation, and retrieval of events and facts form the basis for acquiring new skills and knowledge. Prior knowledge can enhance those memory processes considerably and thus foster knowledge acquisition. But prior knowledge can also hinder knowledge acquisition, in particular when the to-be-learned information is inconsistent with…
The information science of microbial ecology.
Hahn, Aria S; Konwar, Kishori M; Louca, Stilianos; Hanson, Niels W; Hallam, Steven J
2016-06-01
A revolution is unfolding in microbial ecology where petabytes of 'multi-omics' data are produced using next generation sequencing and mass spectrometry platforms. This cornucopia of biological information has enormous potential to reveal the hidden metabolic powers of microbial communities in natural and engineered ecosystems. However, to realize this potential, the development of new technologies and interpretative frameworks grounded in ecological design principles are needed to overcome computational and analytical bottlenecks. Here we explore the relationship between microbial ecology and information science in the era of cloud-based computation. We consider microorganisms as individual information processing units implementing a distributed metabolic algorithm and describe developments in ecoinformatics and ubiquitous computing with the potential to eliminate bottlenecks and empower knowledge creation and translation. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.
Systematic reviews, systematic error and the acquisition of clinical knowledge
2010-01-01
Background Since its inception, evidence-based medicine and its application through systematic reviews, has been widely accepted. However, it has also been strongly criticised and resisted by some academic groups and clinicians. One of the main criticisms of evidence-based medicine is that it appears to claim to have unique access to absolute scientific truth and thus devalues and replaces other types of knowledge sources. Discussion The various types of clinical knowledge sources are categorised on the basis of Kant's categories of knowledge acquisition, as being either 'analytic' or 'synthetic'. It is shown that these categories do not act in opposition but rather, depend upon each other. The unity of analysis and synthesis in knowledge acquisition is demonstrated during the process of systematic reviewing of clinical trials. Systematic reviews constitute comprehensive synthesis of clinical knowledge but depend upon plausible, analytical hypothesis development for the trials reviewed. The dangers of systematic error regarding the internal validity of acquired knowledge are highlighted on the basis of empirical evidence. It has been shown that the systematic review process reduces systematic error, thus ensuring high internal validity. It is argued that this process does not exclude other types of knowledge sources. Instead, amongst these other types it functions as an integrated element during the acquisition of clinical knowledge. Conclusions The acquisition of clinical knowledge is based on interaction between analysis and synthesis. Systematic reviews provide the highest form of synthetic knowledge acquisition in terms of achieving internal validity of results. In that capacity it informs the analytic knowledge of the clinician but does not replace it. PMID:20537172
USDA-ARS?s Scientific Manuscript database
Monodactylus sebae is a popular euryhaline ornamental fish species with limited aquaculture production. One of the bottlenecks to their commercial production has been knowledge of broodstock nutritional requirements. Therefore, three brood diets were formulated and fed to M. sebae brood to determine...
Examinations and Educational Opportunity in China: Mobility and Bottlenecks for the Rural Poor
ERIC Educational Resources Information Center
Hannum, Emily; An, Xuehui; Cherng, Hua-Yu Sebastian
2011-01-01
Despite the important role played by examinations in educational stratification and mobility in China, to our knowledge there is no literature in English that investigates the impact of exams on educational attainment with empirical data. We address this gap with an investigation of how examinations shape opportunities for children of the rural…
Structuration and acquisition of medical knowledge. Using UMLS in the conceptual graph formalism.
Volot, F.; Zweigenbaum, P.; Bachimont, B.; Ben Said, M.; Bouaud, J.; Fieschi, M.; Boisvieux, J. F.
1993-01-01
The use of a taxonomy, such as the concept type lattice (CTL) of Conceptual Graphs, is a central structuring piece in a knowledge-based system. The knowledge it contains is constantly used by the system, and its structure provides a guide for the acquisition of other pieces of knowledge. We show how UMLS can be used as a knowledge resource to build a CTL and how the CTL can help the process of acquisition for other kinds of knowledge. We illustrate this method in the context of the MENELAS natural language understanding project. PMID:8130568
Knowledge Acquisition, Knowledge Programming, and Knowledge Refinement.
ERIC Educational Resources Information Center
Hayes-Roth, Frederick; And Others
This report describes the principal findings and recommendations of a 2-year Rand research project on machine-aided knowledge acquisition and discusses the transfer of expertise from humans to machines, as well as the functions of planning, debugging, knowledge refinement, and autonomous machine learning. The relative advantages of humans and…
Integrating multiparametric prostate MRI into clinical practice
2011-01-01
Abstract Multifunctional magnetic resonance imaging (MRI) techniques are increasingly being used to address bottlenecks in prostate cancer patient management. These techniques yield qualitative, semi-quantitative and fully quantitative biomarkers that reflect on the underlying biological status of a tumour. If these techniques are to have a role in patient management, then standard methods of data acquisition, analysis and reporting have to be developed. Effective communication by the use of scoring systems, structured reporting and a graphical interface that matches prostate anatomy are key elements. Practical guidelines for integrating multiparametric MRI into clinical practice are presented. PMID:22187067
ERIC Educational Resources Information Center
Dahiyat, Samer E.
2015-01-01
The aim of this research is to empirically investigate the relationships among the three vital knowledge management processes of acquisition, integration and application, and their effects on organisational innovation in the pharmaceutical manufacturing industry in Jordan; a knowledge-intensive business service (KIBS) sector. Structural equation…
The Human Side of Knowledge Management: An Annotated Bibliography.
ERIC Educational Resources Information Center
Mayer, Pamela S.
This annotated bibliography lists books and articles that have direct application to managing the human side of knowledge acquisition, transfer, and application. What is meant by the human dimension of knowledge is how motivation and learning affect the acquisition and transfer of knowledge and how group dynamics mediate the role of knowledge in…
Documentation and knowledge acquisition
NASA Technical Reports Server (NTRS)
Rochowiak, Daniel; Moseley, Warren
1990-01-01
Traditional approaches to knowledge acquisition have focused on interviews. An alternative focuses on the documentation associated with a domain. Adopting a documentation approach provides some advantages during familiarization. A knowledge management tool was constructed to gain these advantages.
Liu, Hu-Chen; Liu, Long; Lin, Qing-Lian; Liu, Nan
2013-06-01
The two most important issues of expert systems are the acquisition of domain experts' professional knowledge and the representation and reasoning of the knowledge rules that have been identified. First, during expert knowledge acquisition processes, the domain expert panel often demonstrates different experience and knowledge from one another and produces different types of knowledge information such as complete and incomplete, precise and imprecise, and known and unknown because of its cross-functional and multidisciplinary nature. Second, as a promising tool for knowledge representation and reasoning, fuzzy Petri nets (FPNs) still suffer a couple of deficiencies. The parameters in current FPN models could not accurately represent the increasingly complex knowledge-based systems, and the rules in most existing knowledge inference frameworks could not be dynamically adjustable according to propositions' variation as human cognition and thinking. In this paper, we present a knowledge acquisition and representation approach using the fuzzy evidential reasoning approach and dynamic adaptive FPNs to solve the problems mentioned above. As is illustrated by the numerical example, the proposed approach can well capture experts' diversity experience, enhance the knowledge representation power, and reason the rule-based knowledge more intelligently.
Innovative UK Approaches to Acquisition Management
2009-05-01
Financial and Operational Imperatives Size of UK armed forces UK Industry ? Political influence PFI / PPP Increased Scrutiny - NAO “ Commercialisation “ of the...acquisition KNOWLEDGE (EXPERIENCE – Lessons learned) KNOWLEDGE (Training) KNOWLEDGE ( Education ) OPTIMAL OPERATIONAL PERFORMANCE Operational Capability UK
Marsden, Clare D; Ortega-Del Vecchyo, Diego; O'Brien, Dennis P; Taylor, Jeremy F; Ramirez, Oscar; Vilà, Carles; Marques-Bonet, Tomas; Schnabel, Robert D; Wayne, Robert K; Lohmueller, Kirk E
2016-01-05
Population bottlenecks, inbreeding, and artificial selection can all, in principle, influence levels of deleterious genetic variation. However, the relative importance of each of these effects on genome-wide patterns of deleterious variation remains controversial. Domestic and wild canids offer a powerful system to address the role of these factors in influencing deleterious variation because their history is dominated by known bottlenecks and intense artificial selection. Here, we assess genome-wide patterns of deleterious variation in 90 whole-genome sequences from breed dogs, village dogs, and gray wolves. We find that the ratio of amino acid changing heterozygosity to silent heterozygosity is higher in dogs than in wolves and, on average, dogs have 2-3% higher genetic load than gray wolves. Multiple lines of evidence indicate this pattern is driven by less efficient natural selection due to bottlenecks associated with domestication and breed formation, rather than recent inbreeding. Further, we find regions of the genome implicated in selective sweeps are enriched for amino acid changing variants and Mendelian disease genes. To our knowledge, these results provide the first quantitative estimates of the increased burden of deleterious variants directly associated with domestication and have important implications for selective breeding programs and the conservation of rare and endangered species. Specifically, they highlight the costs associated with selective breeding and question the practice favoring the breeding of individuals that best fit breed standards. Our results also suggest that maintaining a large population size, rather than just avoiding inbreeding, is a critical factor for preventing the accumulation of deleterious variants.
Marsden, Clare D.; Ortega-Del Vecchyo, Diego; O’Brien, Dennis P.; Taylor, Jeremy F.; Ramirez, Oscar; Vilà, Carles; Marques-Bonet, Tomas; Schnabel, Robert D.; Wayne, Robert K.; Lohmueller, Kirk E.
2016-01-01
Population bottlenecks, inbreeding, and artificial selection can all, in principle, influence levels of deleterious genetic variation. However, the relative importance of each of these effects on genome-wide patterns of deleterious variation remains controversial. Domestic and wild canids offer a powerful system to address the role of these factors in influencing deleterious variation because their history is dominated by known bottlenecks and intense artificial selection. Here, we assess genome-wide patterns of deleterious variation in 90 whole-genome sequences from breed dogs, village dogs, and gray wolves. We find that the ratio of amino acid changing heterozygosity to silent heterozygosity is higher in dogs than in wolves and, on average, dogs have 2–3% higher genetic load than gray wolves. Multiple lines of evidence indicate this pattern is driven by less efficient natural selection due to bottlenecks associated with domestication and breed formation, rather than recent inbreeding. Further, we find regions of the genome implicated in selective sweeps are enriched for amino acid changing variants and Mendelian disease genes. To our knowledge, these results provide the first quantitative estimates of the increased burden of deleterious variants directly associated with domestication and have important implications for selective breeding programs and the conservation of rare and endangered species. Specifically, they highlight the costs associated with selective breeding and question the practice favoring the breeding of individuals that best fit breed standards. Our results also suggest that maintaining a large population size, rather than just avoiding inbreeding, is a critical factor for preventing the accumulation of deleterious variants. PMID:26699508
Evaluation, Use, and Refinement of Knowledge Representations through Acquisition Modeling
ERIC Educational Resources Information Center
Pearl, Lisa
2017-01-01
Generative approaches to language have long recognized the natural link between theories of knowledge representation and theories of knowledge acquisition. The basic idea is that the knowledge representations provided by Universal Grammar enable children to acquire language as reliably as they do because these representations highlight the…
Ferguson, Eamonn; Semper, Heather; Yates, Janet; Fitzgerald, J Edward; Skatova, Anya; James, David
2014-01-01
Theory suggests that personality traits evolved to have costs and benefits, with the effectiveness of a trait dependent on how these costs and benefits relate to the present circumstances. This suggests that traits that are generally viewed as positive can have a 'dark side' and those generally viewed as negative can have a 'bright side' depending on changes in context. We test this in a sample of 220 UK medical students with respect to associations between the Big 5 personality traits and learning outcomes across the 5 years of a medical degree. The medical degree offers a changing learning context from pre-clinical years (where a more methodical approach to learning is needed) to the clinical years (where more flexible learning is needed, in a more stressful context). We argue that while trait conscientiousness should enhance pre-clinical learning, it has a 'dark side' reducing the acquisition of knowledge in the clinical years. We also suggest that anxiety has a 'bright side' enhancing the acquisition of skills in the clinical years. We also explore if intelligence enhances learning across the medical degree. Using confirmatory factor analysis and structural equation modelling we show that medical skills and knowledge assessed in the pre-clinical and clinical years are psychometrically distinguishable, forming a learning 'backbone', whereby subsequent learning outcomes are predicted by previous ones. Consistent with our predictions conscientiousness enhanced preclinical knowledge acquisition but reduced the acquisition of clinical knowledge and anxiety enhanced the acquisition of clinical skills. We also identified a curvilinear U shaped association between Surgency (extraversion) and pre-clinical knowledge acquisition. Intelligence predicted initial clinical knowledge, and had a positive total indirect effect on clinical knowledge and clinical skill acquisition. For medical selection, this suggests that selecting students high on conscientiousness may be problematic, as it may be excluding those with some degree of moderate anxiety.
Ferguson, Eamonn; Semper, Heather; Yates, Janet; Fitzgerald, J. Edward; Skatova, Anya; James, David
2014-01-01
Theory suggests that personality traits evolved to have costs and benefits, with the effectiveness of a trait dependent on how these costs and benefits relate to the present circumstances. This suggests that traits that are generally viewed as positive can have a ‘dark side’ and those generally viewed as negative can have a ‘bright side’ depending on changes in context. We test this in a sample of 220 UK medical students with respect to associations between the Big 5 personality traits and learning outcomes across the 5 years of a medical degree. The medical degree offers a changing learning context from pre-clinical years (where a more methodical approach to learning is needed) to the clinical years (where more flexible learning is needed, in a more stressful context). We argue that while trait conscientiousness should enhance pre-clinical learning, it has a ‘dark side’ reducing the acquisition of knowledge in the clinical years. We also suggest that anxiety has a ‘bright side’ enhancing the acquisition of skills in the clinical years. We also explore if intelligence enhances learning across the medical degree. Using confirmatory factor analysis and structural equation modelling we show that medical skills and knowledge assessed in the pre-clinical and clinical years are psychometrically distinguishable, forming a learning ‘backbone’, whereby subsequent learning outcomes are predicted by previous ones. Consistent with our predictions conscientiousness enhanced preclinical knowledge acquisition but reduced the acquisition of clinical knowledge and anxiety enhanced the acquisition of clinical skills. We also identified a curvilinear U shaped association between Surgency (extraversion) and pre-clinical knowledge acquisition. Intelligence predicted initial clinical knowledge, and had a positive total indirect effect on clinical knowledge and clinical skill acquisition. For medical selection, this suggests that selecting students high on conscientiousness may be problematic, as it may be excluding those with some degree of moderate anxiety. PMID:24586353
Research on Production Scheduling System with Bottleneck Based on Multi-agent
NASA Astrophysics Data System (ADS)
Zhenqiang, Bao; Weiye, Wang; Peng, Wang; Pan, Quanke
Aimed at the imbalance problem of resource capacity in Production Scheduling System, this paper uses Production Scheduling System based on multi-agent which has been constructed, and combines the dynamic and autonomous of Agent; the bottleneck problem in the scheduling is solved dynamically. Firstly, this paper uses Bottleneck Resource Agent to find out the bottleneck resource in the production line, analyses the inherent mechanism of bottleneck, and describes the production scheduling process based on bottleneck resource. Bottleneck Decomposition Agent harmonizes the relationship of job's arrival time and transfer time in Bottleneck Resource Agent and Non-Bottleneck Resource Agents, therefore, the dynamic scheduling problem is simplified as the single machine scheduling of each resource which takes part in the scheduling. Finally, the dynamic real-time scheduling problem is effectively solved in Production Scheduling System.
Manage Toward Success - Utilization of Analytics in Acquisition Decision Making
2015-04-01
on the concept of knowledge- based acquisition described by the GAO. In the GAO (2005) report for National Aeronautics and Space Administration ( NASA ...acquisition programs, GAO recommended to NASA , and NASA subsequently con- curred, that transition to a knowledge-based acquisition framework will...Certification and Accreditation Process; ERAM = Enterprise Risk Assessment Manager; EVMS = Earned Value Management System; GOV = Government; POA&M = Plan of
Conceptual Knowledge Acquisition in Biomedicine: A Methodological Review
Payne, Philip R.O.; Mendonça, Eneida A.; Johnson, Stephen B.; Starren, Justin B.
2007-01-01
The use of conceptual knowledge collections or structures within the biomedical domain is pervasive, spanning a variety of applications including controlled terminologies, semantic networks, ontologies, and database schemas. A number of theoretical constructs and practical methods or techniques support the development and evaluation of conceptual knowledge collections. This review will provide an overview of the current state of knowledge concerning conceptual knowledge acquisition, drawing from multiple contributing academic disciplines such as biomedicine, computer science, cognitive science, education, linguistics, semiotics, and psychology. In addition, multiple taxonomic approaches to the description and selection of conceptual knowledge acquisition and evaluation techniques will be proposed in order to partially address the apparent fragmentation of the current literature concerning this domain. PMID:17482521
ERIC Educational Resources Information Center
Secret, Mary; Abell, Melissa L.; Ward, Christopher J.; Charles, Jennifer L. K.; Perkins, Nathan H.
2017-01-01
In response to the need for meaningful data about student learning in research courses, we developed and implemented the Research Knowledge Assessment instrument to measure MSW student acquisition, application, and retention of research knowledge over a 3-year period across the research curriculum. Initial findings indicated that students entered…
Impacts of moving bottlenecks on traffic flow
NASA Astrophysics Data System (ADS)
Ou, Hui; Tang, Tie-Qiao
2018-06-01
Bottleneck (especially the moving bottleneck) widely exists in the urban traffic system. However, little effort has been made to study the impacts of the moving bottleneck on traffic flow (especially the evolution and propagation of traffic flow). In this article, we introduce the speed of a moving bottleneck into a traffic flow model, then propose an extended macro traffic flow with a moving bottleneck, and finally use the proposed model to study the effects of a moving bottleneck on the evolution and propagation of traffic flow under uniform flow and a small perturbation. The numerical results indicate that the moving bottleneck has prominent influences on the evolution of traffic flow under the two typical traffic situations and that the impacts are dependent on the initial density.
A knowledge engineering taxonomy for intelligent tutoring system development
NASA Technical Reports Server (NTRS)
Fink, Pamela K.; Herren, L. Tandy
1993-01-01
This paper describes a study addressing the issue of developing an appropriate mapping of knowledge acquisition methods to problem types for intelligent tutoring system development. Recent research has recognized that knowledge acquisition methodologies are not general across problem domains; the effectiveness of a method for obtaining knowledge depends on the characteristics of the domain and problem solving task. Southwest Research Institute developed a taxonomy of problem types by evaluating the characteristics that discriminate between problems and grouping problems that share critical characteristics. Along with the problem taxonomy, heuristics that guide the knowledge acquisition process based on the characteristics of the class are provided.
Hannan, Thomas J.; Totsika, Makrina; Mansfield, Kylie J.; Moore, Kate H.; Schembri, Mark A.; Hultgren, Scott J.
2013-01-01
Bladder infections affect millions of people yearly, and recurrent symptomatic infections (cystitis) are very common. The rapid increase in infections caused by multi-drug resistant uropathogens threatens to make recurrent cystitis an increasingly troubling public health concern. Uropathogenic E. coli (UPEC) cause the vast majority of bladder infections. Upon entry into the lower urinary tract, UPEC face obstacles to colonization that constitute population bottlenecks, reducing diversity and selecting for fit clones. A critical mucosal barrier to bladder infection is the epithelium (urothelium). UPEC bypass this barrier when they invade urothelial cells and form intracellular bacterial communities (IBCs), a process which requires type 1 pili. IBCs are transient in nature, occurring primarily during acute infection. Chronic bladder infection is common and can be either latent, in the form of the Quiescent Intracellular Reservoir (QIR), or active, in the form of asymptomatic bacteriuria (ASB/ABU) or chronic cystitis. In mice, the fate of bladder infection: QIR, ASB, or chronic cystitis, is determined within the first 24 hours of infection and constitutes a putative host-pathogen mucosal checkpoint that contributes to susceptibility to recurrent cystitis. Knowledge of these checkpoints and bottlenecks is critical for our understanding of bladder infection and efforts to devise novel therapeutic strategies. PMID:22404313
NASA Astrophysics Data System (ADS)
Wilde, Matthias; Hußmann, Jona Samuel; Lorenzen, Simone; Meyer, Annika; Randler, Christoph
2012-12-01
The aim of this study was to evaluate the effects of living animals on pupils' intrinsic motivation and knowledge. Various studies from the late 1970s and 1980s stress the high effectiveness of authentic learning experiences in pupils' knowledge acquisition. However, there are only few current empirical studies on this topic. The research question of our study is to assess whether the use of living animals in the biology classroom supports intrinsic motivation and knowledge acquisition. In a pre-/post-test design, 185 fifth graders received two different treatments: the experimental group (N = 74) was taught with living harvest mice (Micromys minutus) and the control group (N = 111) received lessons with the same content which was presented in short film clips on laptop computers. Knowledge acquisition was assessed with open-ended and closed questions, while intrinsic motivation was tested with an adapted version of the Intrinsic Motivation Inventory (IMI). There were no differences in knowledge acquisition between the treatments. However, the results of the IMI showed significant differences in favour of the experimental group in interest/enjoyment, perceived competence, and perceived autonomy. Thus, living animals exert a positive influence on motivation.
Visual Knowledge in Tactical Planning: Preliminary Knowledge Acquisition Phase 1 Technical Report
1990-04-05
MANAGEMENT INFORMATION , COMMUNICATIONS, AND COMPUTER SCIENCES Visual Knowledge in Tactical Planning: Preliminary Knowledge Acquisition Phase I Technical...perceived provides information in multiple modalities and, in fact, we may rely on a non-verbal mode for much of our understanding of the situation...some tasks, almost all the pertinent information is provided via diagrams, maps, znd other illustrations. Visual Knowledge Visual experience forms a
2017-01-01
ABSTRACT The field of microbiology has experienced significant growth due to transformative advances in technology and the influx of scientists driven by a curiosity to understand how microbes sustain myriad biochemical processes that maintain Earth. With this explosion in scientific output, a significant bottleneck has been the ability to rapidly disseminate new knowledge to peers and the public. Preprints have emerged as a tool that a growing number of microbiologists are using to overcome this bottleneck. Posting preprints can help to transparently recruit a more diverse pool of reviewers prior to submitting to a journal for formal peer review. Although the use of preprints is still limited in the biological sciences, early indications are that preprints are a robust tool that can complement and enhance peer-reviewed publications. As publishing moves to embrace advances in Internet technology, there are many opportunities for preprints and peer-reviewed journals to coexist in the same ecosystem. PMID:28536284
Schloss, Patrick D
2017-05-23
The field of microbiology has experienced significant growth due to transformative advances in technology and the influx of scientists driven by a curiosity to understand how microbes sustain myriad biochemical processes that maintain Earth. With this explosion in scientific output, a significant bottleneck has been the ability to rapidly disseminate new knowledge to peers and the public. Preprints have emerged as a tool that a growing number of microbiologists are using to overcome this bottleneck. Posting preprints can help to transparently recruit a more diverse pool of reviewers prior to submitting to a journal for formal peer review. Although the use of preprints is still limited in the biological sciences, early indications are that preprints are a robust tool that can complement and enhance peer-reviewed publications. As publishing moves to embrace advances in Internet technology, there are many opportunities for preprints and peer-reviewed journals to coexist in the same ecosystem. Copyright © 2017 Schloss.
Collaborative modelling: the future of computational neuroscience?
Davison, Andrew P
2012-01-01
Given the complexity of biological neural circuits and of their component cells and synapses, building and simulating robust, well-validated, detailed models increasingly surpasses the resources of an individual researcher or small research group. In this article, I will briefly review possible solutions to this problem, argue for open, collaborative modelling as the optimal solution for advancing neuroscience knowledge, and identify potential bottlenecks and possible solutions.
Science Teachers' Epistemic Cognition in Instructional Decision Making
ERIC Educational Resources Information Center
Ponnock, Annette R.
2017-01-01
One understudied barrier to science education reform concerns teachers' cognitive processes and how they relate to instructional decision-making. Epistemic cognition--teachers' beliefs about knowledge and knowledge acquisition and goals for their students' knowledge acquisition--could provide important insights into the choices science teachers…
TARGET's role in knowledge acquisition, engineering, validation, and documentation
NASA Technical Reports Server (NTRS)
Levi, Keith R.
1994-01-01
We investigate the use of the TARGET task analysis tool for use in the development of rule-based expert systems. We found TARGET to be very helpful in the knowledge acquisition process. It enabled us to perform knowledge acquisition with one knowledge engineer rather than two. In addition, it improved communication between the domain expert and knowledge engineer. We also found it to be useful for both the rule development and refinement phases of the knowledge engineering process. Using the network in these phases required us to develop guidelines that enabled us to easily translate the network into production rules. A significant requirement for TARGET remaining useful throughout the knowledge engineering process was the need to carefully maintain consistency between the network and the rule representations. Maintaining consistency not only benefited the knowledge engineering process, but also has significant payoffs in the areas of validation of the expert system and documentation of the knowledge in the system.
Some Aspects of Developing Background Knowledge in Second Language Acquisition Revisited
ERIC Educational Resources Information Center
Zashchitina, Galina; Moysyak, Natalia
2017-01-01
The article focuses on defining how background knowledge impacts on second-language acquisition by giving a brief overview of schema theory, the interaction of the basic modes of information processing. A challenge of dealing with culturally specific texts in second language acquisition is also touched upon. Different research-supported views on…
Computational Modeling for Language Acquisition: A Tutorial With Syntactic Islands.
Pearl, Lisa S; Sprouse, Jon
2015-06-01
Given the growing prominence of computational modeling in the acquisition research community, we present a tutorial on how to use computational modeling to investigate learning strategies that underlie the acquisition process. This is useful for understanding both typical and atypical linguistic development. We provide a general overview of why modeling can be a particularly informative tool and some general considerations when creating a computational acquisition model. We then review a concrete example of a computational acquisition model for complex structural knowledge referred to as syntactic islands. This includes an overview of syntactic islands knowledge, a precise definition of the acquisition task being modeled, the modeling results, and how to meaningfully interpret those results in a way that is relevant for questions about knowledge representation and the learning process. Computational modeling is a powerful tool that can be used to understand linguistic development. The general approach presented here can be used to investigate any acquisition task and any learning strategy, provided both are precisely defined.
Knowledge Acquisition and Readiness Assurance Testing: The Connected Notes Intervention
ERIC Educational Resources Information Center
Young, Mark R.
2016-01-01
The responsibility for knowledge acquisition is increasingly being shifted to students though the utilization of experiential learning, teamwork, online, and flipped classroom pedagogies. Students are expected to enter the classroom prepared to engage in thoughtful knowledge application activities; however, many students have not adequately…
Retrieval Enhances Route Knowledge Acquisition, but Only When Movement Errors Are Prevented
ERIC Educational Resources Information Center
Kelly, Jonathan W.; Carpenter, Shana K.; Sjolund, Lori A.
2015-01-01
Studies of the "testing effect" have shown that retrieval significantly improves learning. However, most of these studies have been restricted to simple types of declarative verbal knowledge. Five experiments were designed to explore whether testing improves acquisition of route knowledge, which has a procedural component consisting of…
ERIC Educational Resources Information Center
Markert, Ronald J.; O'Neill, Sally C.; Bhatia, Subhash C.
2003-01-01
Introduction: The objectives of continuing medical education (CME) programs include knowledge acquisition, skill development, clinical reasoning and decision making, and health care outcomes. We conducted a yearlong medical education research study in which knowledge acquisition in our CME programs was assessed. Method: A randomized…
Sources of Knowledge Acquisition: Perspectives of the High School Teacher/Coach
ERIC Educational Resources Information Center
Wilson, Laurie M.; Bloom, Gordon A.; Harvey, William J.
2010-01-01
Background: Research on coach development and knowledge acquisition has traditionally focused on those working at either university or Olympic levels. Despite the large body of research using these participants, there are relatively few empirical studies on the knowledge development of high school coaches, in particular, physical education…
Nurturing Phonemic Awareness and Alphabetic Knowledge in Pre-Kindergartners.
ERIC Educational Resources Information Center
Steinhaus, Patricia L.
Reading research continues to identify phonemic awareness and knowledge of the alphabetic principle as key factors in the literacy acquisition process and to indicate that they greatly facilitate decoding efforts. While research indicates that phonemic awareness and alphabetic knowledge are necessary to literacy acquisition, many early childhood…
Acquisition of Three Word Knowledge Aspects through Reading
ERIC Educational Resources Information Center
Daskalovska, Nina
2016-01-01
A number of studies have shown that second or foreign language learners can acquire vocabulary through reading. The aim of the study was to investigate (a) the effects of reading an authentic novel on the acquisition of 3 aspects of word knowledge: spelling, meaning, and collocation; (b) the influence of reading on the acquisition of partial and…
Defense Acquisitions: Assessments of Selected Weapon Programs
2015-03-01
offices on technology, design , and manufacturing knowledge; the use of knowledge- based acquisition practices; and the implementation of acquisition...and production maturity using two data-collection instruments, including a questionnaire on issues such as systems engineering reviews, design ...Demonstrating technology maturity is a prerequisite for moving forward into system development, during which the focus should be on design and
Reijnierse, Esmee M; de van der Schueren, Marian A E; Trappenburg, Marijke C; Doves, Marjan; Meskers, Carel G M; Maier, Andrea B
2017-01-01
Sarcopenia is an emerging clinical challenge in an ageing population and is associated with serious negative health outcomes. This study aimed to assess the current state of the art regarding the knowledge about the concept of sarcopenia and practice of the diagnostic strategy and management of sarcopenia in a cohort of Dutch healthcare professionals (physicians, physiotherapists, dietitians and others) attending a lecture cycle on sarcopenia. This longitudinal study included Dutch healthcare professionals (n = 223) who were asked to complete a questionnaire before, directly after and five months after (n = 80) attending a lecture cycle on the pathophysiology of sarcopenia, diagnostic strategy and management of sarcopenia, i.e. interventions and collaboration. Before attendance, 69.7% of healthcare professionals stated to know the concept of sarcopenia, 21.4% indicated to know how to diagnose sarcopenia and 82.6% had treated patients with suspected sarcopenia. 47.5% used their clinical view as diagnostic strategy. Handgrip strength was the most frequently used objective diagnostic measure (33.9%). Five months after attendance, reported use of diagnostic tests was increased, i.e. handgrip strength up to 67.4%, gait speed up to 72.1% and muscle mass up to 20.9%. Bottlenecks during implementation of the diagnostic strategy were experienced by 67.1%; lack of awareness among other healthcare professionals, acquisition of equipment and time constraints to perform the diagnostic measures were reported most often. Before attendance, 36.4% stated not to consult a physiotherapists or exercise therapists (PT/ET) or dietitian for sarcopenia interventions, 10.5% consulted a PT/ET, 32.7% a dietitian and 20.5% both a PT/ET and dietitian. Five months after attendance, these percentages were 28.3%, 21.7%, 30.0% and 20.0% respectively. The concept of sarcopenia is familiar to most Dutch healthcare professionals but application in practice is hampered, mostly by lack of knowledge, availability of equipment, time constraints and lack of collaboration.
Reijnierse, Esmee M.; de van der Schueren, Marian A. E.; Trappenburg, Marijke C.; Doves, Marjan; Meskers, Carel G. M.
2017-01-01
Objectives Sarcopenia is an emerging clinical challenge in an ageing population and is associated with serious negative health outcomes. This study aimed to assess the current state of the art regarding the knowledge about the concept of sarcopenia and practice of the diagnostic strategy and management of sarcopenia in a cohort of Dutch healthcare professionals (physicians, physiotherapists, dietitians and others) attending a lecture cycle on sarcopenia. Material and methods This longitudinal study included Dutch healthcare professionals (n = 223) who were asked to complete a questionnaire before, directly after and five months after (n = 80) attending a lecture cycle on the pathophysiology of sarcopenia, diagnostic strategy and management of sarcopenia, i.e. interventions and collaboration. Results Before attendance, 69.7% of healthcare professionals stated to know the concept of sarcopenia, 21.4% indicated to know how to diagnose sarcopenia and 82.6% had treated patients with suspected sarcopenia. 47.5% used their clinical view as diagnostic strategy. Handgrip strength was the most frequently used objective diagnostic measure (33.9%). Five months after attendance, reported use of diagnostic tests was increased, i.e. handgrip strength up to 67.4%, gait speed up to 72.1% and muscle mass up to 20.9%. Bottlenecks during implementation of the diagnostic strategy were experienced by 67.1%; lack of awareness among other healthcare professionals, acquisition of equipment and time constraints to perform the diagnostic measures were reported most often. Before attendance, 36.4% stated not to consult a physiotherapists or exercise therapists (PT/ET) or dietitian for sarcopenia interventions, 10.5% consulted a PT/ET, 32.7% a dietitian and 20.5% both a PT/ET and dietitian. Five months after attendance, these percentages were 28.3%, 21.7%, 30.0% and 20.0% respectively. Conclusion The concept of sarcopenia is familiar to most Dutch healthcare professionals but application in practice is hampered, mostly by lack of knowledge, availability of equipment, time constraints and lack of collaboration. PMID:28968456
NASA Astrophysics Data System (ADS)
1981-01-01
Oklahoma City Police Department developed a computerized communications system, based on Johnson Space Center's (JSC's) 1960-mission control knowledge. JSC furnished information on lighting and other fatigue reducing measures, and provided specifications for equipment and design layouts. JSC also advised OCPD how to avoid communications bottlenecks associated with simultaneous handling of telephone, radio and inner-office transmissions. Oklahoma City saved money in reduced design and engineering costs by utilizing the already developed NASA technology.
Sobel Leonard, Ashley; Weissman, Daniel B; Greenbaum, Benjamin; Ghedin, Elodie; Koelle, Katia
2017-07-15
The bottleneck governing infectious disease transmission describes the size of the pathogen population transferred from the donor to the recipient host. Accurate quantification of the bottleneck size is particularly important for rapidly evolving pathogens such as influenza virus, as narrow bottlenecks reduce the amount of transferred viral genetic diversity and, thus, may decrease the rate of viral adaptation. Previous studies have estimated bottleneck sizes governing viral transmission by using statistical analyses of variants identified in pathogen sequencing data. These analyses, however, did not account for variant calling thresholds and stochastic viral replication dynamics within recipient hosts. Because these factors can skew bottleneck size estimates, we introduce a new method for inferring bottleneck sizes that accounts for these factors. Through the use of a simulated data set, we first show that our method, based on beta-binomial sampling, accurately recovers transmission bottleneck sizes, whereas other methods fail to do so. We then apply our method to a data set of influenza A virus (IAV) infections for which viral deep-sequencing data from transmission pairs are available. We find that the IAV transmission bottleneck size estimates in this study are highly variable across transmission pairs, while the mean bottleneck size of 196 virions is consistent with a previous estimate for this data set. Furthermore, regression analysis shows a positive association between estimated bottleneck size and donor infection severity, as measured by temperature. These results support findings from experimental transmission studies showing that bottleneck sizes across transmission events can be variable and influenced in part by epidemiological factors. IMPORTANCE The transmission bottleneck size describes the size of the pathogen population transferred from the donor to the recipient host and may affect the rate of pathogen adaptation within host populations. Recent advances in sequencing technology have enabled bottleneck size estimation from pathogen genetic data, although there is not yet a consistency in the statistical methods used. Here, we introduce a new approach to infer the bottleneck size that accounts for variant identification protocols and noise during pathogen replication. We show that failing to account for these factors leads to an underestimation of bottleneck sizes. We apply this method to an existing data set of human influenza virus infections, showing that transmission is governed by a loose, but highly variable, transmission bottleneck whose size is positively associated with the severity of infection of the donor. Beyond advancing our understanding of influenza virus transmission, we hope that this work will provide a standardized statistical approach for bottleneck size estimation for viral pathogens. Copyright © 2017 Sobel Leonard et al.
Dale L. Bartos; Kent B. Downing
1989-01-01
A knowledge acquisition program was written to aid in obtaining knowledge from the experts concerning endemic populations of mountain pine beetle in lodgepole pine forest. An application expert system is then automatically generated by the knowledge acquisition program that contains the codified base of expert knowledge. Data can then be entered into the expert system...
Knowledge Acquisition: A Review of Tools and Ideas.
1987-08-01
tools. However, none could be applied directly to solving the problem of acquiring knowledge for the ASPA. RECOMMENDATIONS Develop a tool based on...the social sciences. BACKGROUND Because of the newness and complexity of the knowledge acquisition problem, the background of the knowledge...4. Minimal (does not incorporate any unnecessary complexities ) 5. Expected (experts are not in disagreement over any important aspect) (Grover 1983
Gallois, Sandrine; Duda, Romain; Hewlett, Barry; Reyes-García, Victoria
2015-12-24
The acquisition of local knowledge occurs through complex interactions between individual and contextual characteristics: as context changes, so it changes the acquisition of knowledge. Contemporary small-scale societies facing rapid social-ecological change provide a unique opportunity to study the relation between social-ecological changes and the process of acquisition of local knowledge. In this work, we study children's involvement in subsistence related activities (i.e., hunting and gathering) in a context of social-ecological change and discuss how such involvement might condition the acquisition of local knowledge during childhood. We interviewed 98 children from a hunter-gatherer society, the Baka, living in two different villages in southeastern Cameroon and assessed their involvement in daily activities. Using interviews, we collected self-reported data on the main activities performed during the previous 24 h. We describe the frequency of occurrence of daily activities during middle childhood and adolescence and explore the variation in occurrence according to the sex, the age group, and the village of residency of the child. We also explore variation according to the season in which the activity is conducted and to the predicted potential of the activity for the acquisition of local knowledge. Baka children and adolescents engage in subsistence-related activities (i.e., hunting and gathering) and playing more frequently than in other activities (i.e., traditional tales or schooling). Gender differences in children's subsistence activities emerge at an early age. Engagement in activities also varies with age, with adolescents spending more time in agricultural activities, modern leisure (i.e., going to bars), and socializing than younger children. When conducting similar activities, adolescents use more complex techniques than younger children. Subsistence activities, which present a high potential for transmission of local knowledge, continue to be predominant in Baka childhood. However, Baka children also engage in other, non-traditional activities, such as modern forms of leisure, or schooling, with a low potential for the transmission of local knowledge. Baka children's involvement in non-traditional activities might have unforeseen impacts on the acquisition of local knowledge.
ERIC Educational Resources Information Center
Khoja, Suleiman; Ventura, Frank
1997-01-01
Determines the extent physics textbooks contribute to physics teaching objectives and knowledge acquisition in Libya. Analysis of seventh- through ninth-grade physics textbooks and cognitive demand shows a limited effect of textbook content on knowledge acquisition and educational objectives. Suggestions are made for promoting the acquisition of…
Bukenya, Dominic; Darong, Gabriel; Wamoyi, Joyce; McLean, Estelle; Skovdal, Morten; Ddaaki, William; Ondeng’e, Kenneth; Bonnington, Oliver; Seeley, Janet; Hosegood, Victoria; Wringe, Alison
2017-01-01
Objectives There are concerns that medical pluralism may delay patients’ progression through the HIV cascade-of-care. However, the pathways of impact through which medical pluralism influence the care of people living with HIV (PLHIV) in African settings remain unclear. We sought to establish the manifestation of medical pluralism among PLHIV, and explore mechanisms through which medical pluralism contributes bottlenecks along the HIV care cascade. Methods We conducted a multicountry exploratory qualitative study in seven health and demographic surveillance sites in six eastern and southern African countries: Uganda, Kenya, Tanzania, Malawi, Zimbabwe and South Africa. We interviewed 258 PLHIV at different stages of the HIV cascade-of-care, 48 family members of deceased PLHIV and 53 HIV healthcare workers. Interviews were conducted using shared standardised topic guides, and data managed through NVIVO 8/10/11. We conducted a thematic analysis of healthcare pathways and bottlenecks related to medical pluralism. Results Medical pluralism, manifesting across traditional, faith-based and biomedical health-worlds, contributed to the care cascade bottlenecks for PLHIV through three pathways of impact. First, access to HIV treatment was delayed through the nature of health-related beliefs, knowledge and patient journeys. Second, HIV treatment was interrupted by availability of alternative options, perceived failed treatment and exploitation of PLHIV by opportunistic traders and healers. Lastly, the mixing of biomedical healthcare providers and treatment with traditional and faith-based options fuelled tensions driven by fear of drug-to-drug interactions and mistrust between providers operating in different health-worlds. Conclusion Medical pluralism contributes to delays and interruptions of care along the HIV cascade, and mistrust between health providers. Region-wide interventions and policies are urgently needed in sub-Saharan Africa to minimise potential harm and consequences of medical pluralism for PLHIV. The role of sociocultural beliefs in mediating bottlenecks necessitate adoption of culture-sensitive approaches intervention designs and policy reforms appropriate to the context of sub-Saharan Africa. PMID:28736393
Moshabela, Mosa; Bukenya, Dominic; Darong, Gabriel; Wamoyi, Joyce; McLean, Estelle; Skovdal, Morten; Ddaaki, William; Ondeng'e, Kenneth; Bonnington, Oliver; Seeley, Janet; Hosegood, Victoria; Wringe, Alison
2017-07-01
There are concerns that medical pluralism may delay patients' progression through the HIV cascade-of-care. However, the pathways of impact through which medical pluralism influence the care of people living with HIV (PLHIV) in African settings remain unclear. We sought to establish the manifestation of medical pluralism among PLHIV, and explore mechanisms through which medical pluralism contributes bottlenecks along the HIV care cascade. We conducted a multicountry exploratory qualitative study in seven health and demographic surveillance sites in six eastern and southern African countries: Uganda, Kenya, Tanzania, Malawi, Zimbabwe and South Africa. We interviewed 258 PLHIV at different stages of the HIV cascade-of-care, 48 family members of deceased PLHIV and 53 HIV healthcare workers. Interviews were conducted using shared standardised topic guides, and data managed through NVIVO 8/10/11. We conducted a thematic analysis of healthcare pathways and bottlenecks related to medical pluralism. Medical pluralism, manifesting across traditional, faith-based and biomedical health-worlds, contributed to the care cascade bottlenecks for PLHIV through three pathways of impact. First, access to HIV treatment was delayed through the nature of health-related beliefs, knowledge and patient journeys. Second, HIV treatment was interrupted by availability of alternative options, perceived failed treatment and exploitation of PLHIV by opportunistic traders and healers. Lastly, the mixing of biomedical healthcare providers and treatment with traditional and faith-based options fuelled tensions driven by fear of drug-to-drug interactions and mistrust between providers operating in different health-worlds. Medical pluralism contributes to delays and interruptions of care along the HIV cascade, and mistrust between health providers. Region-wide interventions and policies are urgently needed in sub-Saharan Africa to minimise potential harm and consequences of medical pluralism for PLHIV. The role of sociocultural beliefs in mediating bottlenecks necessitate adoption of culture-sensitive approaches intervention designs and policy reforms appropriate to the context of sub-Saharan Africa. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
[Acquisition of arithmetic knowledge].
Fayol, Michel
2008-01-01
The focus of this paper is on contemporary research on the number counting and arithmetical competencies that emerge during infancy, the preschool years, and the elementary school. I provide a brief overview of the evolution of children's conceptual knowledge of arithmetic knowledge, the acquisition and use of counting and how they solve simple arithmetic problems (e.g. 4 + 3).
Learning a New Curricular Approach: Mechanisms of Knowledge Acquisition in Preservice Teachers.
ERIC Educational Resources Information Center
Rovegno, Inez
1992-01-01
Reports a study of preservice physical educators' acquisition of knowledge of a nontraditional movement approach to physical education. Interviews and field observations indicated that before student teaching their knowledge of deeper content objectives was weak. In early field experiences, students attended to aspects of the approach relevant to…
NASA Technical Reports Server (NTRS)
Ruthruff, Eric; Johnston, James C.; Van Selst, Mark; Whitsell, Shelly; Remington, Roger
2003-01-01
Practice can, in some cases, largely eliminate measured dual-task interference. Does this absence of interference indicate the absence of a processing bottleneck (defined as an inability to carry out certain stages in parallel)? The authors show that a bottleneck need not produce any observable interference, provided that there is no temporal overlap in the demand for bottleneck stages on the 2 tasks. Such a "latent" bottleneck is especially likely after practice, when central stages are short. The authors provide new evidence that a latent bottleneck occurred for a participant who produced no interference in M. Van Selst, E. Ruthruff, and J. C. Johnston (1999). These findings demonstrate that the absence of dual-task interference does not necessarily indicate the absence of a processing bottleneck.
Automatic acquisition of domain and procedural knowledge
NASA Technical Reports Server (NTRS)
Ferber, H. J.; Ali, M.
1988-01-01
The design concept and performance of AKAS, an automated knowledge-acquisition system for the development of expert systems, are discussed. AKAS was developed using the FLES knowledge base for the electrical system of the B-737 aircraft and employs a 'learn by being told' strategy. The system comprises four basic modules, a system administration module, a natural-language concept-comprehension module, a knowledge-classification/extraction module, and a knowledge-incorporation module; details of the module architectures are explored.
Marketing practitioner’s tacit knowledge acquisition using Repertory Grid Technique (RTG)
NASA Astrophysics Data System (ADS)
Azmi, Afdhal; Adriman, Ramzi
2018-05-01
The tacit knowledge of Marketing practitioner’s experts is excellent resources and priceless. It takes into account their experiential, skill, ideas, belief systems, insight and speculation into management decision-making. This expertise is an individual intuitive judgment and personal shortcuts to complete the work efficiently. Tacit knowledge of Marketing practitioner’s experts is one of best problem solutions in marketing strategy, environmental analysis, product management and partner’s relationship. This paper proposes the acquisition method of tacit knowledge from Marketing practitioner’s using Repertory Grid Technique (RGT). The RGT is a software application for tacit acquisition knowledge to provide a systematic approach to capture and acquire the constructs from an individual. The result shows the understanding of RGT could make TKE and MPE get a good result in capturing and acquiring tacit knowledge of Marketing practitioner’s experts.
Wang, Yang; Feng, Ruibing; He, Chengwei; Su, Huanxing; Ma, Huan; Wan, Jian-Bo
2018-08-05
The narrow linear range and the limited scan time of the given ion make the quantification of the features challenging in liquid chromatography-mass spectrometry (LC-MS)-based untargeted metabolomics with the full-scan mode. And metabolite identification is another bottleneck of untargeted analysis owing to the difficulty of acquiring MS/MS information of most metabolites detected. In this study, an integrated workflow was proposed using the newly established multiple ion monitoring mode with time-staggered ion lists (tsMIM) and target-directed data-dependent acquisition with time-staggered ion lists (tsDDA) to improve data acquisition and metabolite identification in UHPLC/Q-TOF MS-based untargeted metabolomics. Compared to the conventional untargeted metabolomics, the proprosed workflow exhibited the better repeatability before and after data normalization. After selecting features with the significant change by statistical analysis, MS/MS information of all these features can be obtained by tsDDA analysis to facilitate metabolite identification. Using time-staggered ion lists, the workflow is more sensitive in data acquisition, especially for the low-abundant features. Moreover, the metabolites with low abundance tend to be wrongly integrated and triggered by full scan-based untargeted analysis with MS E acquisition mode, which can be greatly improved by the proposed workflow. The integrated workflow was also successfully applied to discover serum biosignatures for the genetic modification of fat-1 in mice, which indicated its practicability and great potential in future metabolomics studies. Copyright © 2018 Elsevier B.V. All rights reserved.
Research into the development of a knowledge acquisition taxonomy
NASA Technical Reports Server (NTRS)
Fink, Pamela K.
1991-01-01
Monthly progress reports for September 1990 to January 1991 are given. Topics that are briefly covered include problem solving and learning taxonomies, knowledge acquisition techniques, software design, air traffic control, and space shuttle flight control.
Defense Acquisitions: Assessments of Selected Weapon Programs
2012-03-01
knowledge-based practices. As a result , most of these programs will carry technology, design, and production risks into subsequent phases of the...acquisition process that could result in cost growth or schedule delays. GAO also assessed the implementation of selected acquisition reforms and found...knowledge-based practices. As a result , most of these programs will carry technology, design, and production risks into subsequent phases of the
ERIC Educational Resources Information Center
Schnurr, Matthew A.; De Santo, Elizabeth M.; Green, Amanda D.; Taylor, Alanna
2015-01-01
This article investigates the particular mechanisms through which a role-play simulation impacts student perceptions of knowledge acquisition. Longitudinal data were mobilized in the form of quantitative and qualitative surveys to examine whether the simulation succeeded in increasing knowledge around both content and skills. It then delves deeper…
ERIC Educational Resources Information Center
Zeng, Qingtian; Zhao, Zhongying; Liang, Yongquan
2009-01-01
User's knowledge requirement acquisition and analysis are very important for a personalized or user-adaptive learning system. Two approaches to capture user's knowledge requirement about course content within an e-learning system are proposed and implemented in this paper. The first approach is based on the historical data accumulated by an…
ERIC Educational Resources Information Center
Choi, Jung-Min
2010-01-01
The primary concern in current interaction design is focused on how to help users solve problems and achieve goals more easily and efficiently. While users' sufficient knowledge acquisition of operating a product or system is considered important, their acquisition of problem-solving knowledge in the task domain has largely been disregarded. As a…
ERIC Educational Resources Information Center
Simmons, Ellen Stephanie
1977-01-01
Investigates effects of method of presentation and structure on secondary student's acquisition of knowledge and psychomotor skills in teaching use of the compound microscope. Psychomotor skills and knowledge acquisitions were both found to be directly related to high structure and separated presentations. (SL)
ERIC Educational Resources Information Center
Okulu, Hasan Zühtü; Ünver, Ayse Oguz
2018-01-01
The current research is to give an example to the inquiry-based science teaching implementations for facilitating knowledge acquisition and retention in a short period of time. Thus, the aim of the research is to transfer of acquired knowledge into different situations using sequential inquiry activities, which have challenging questions for…
Knowledge structures and the acquisition of a complex skill.
Day, E A; Arthur, W; Gettman, D
2001-10-01
The purpose of this study was to examine the viability of knowledge structures as an operationalization of learning in the context of a task that required a high degree of skill. Over the course of 3 days, 86 men participated in 9 training sessions and learned a complex video game. At the end of acquisition, participants' knowledge structures were assessed. After a 4-day nonpractice interval, trainees completed tests of skill retention and skill transfer. Findings indicated that the similarity of trainees' knowledge structures to an expert structure was correlated with skill acquisition and was predictive of skill retention and skill transfer. However, the magnitude of these effects was dependent on the method used to derive the expert referent structure. Moreover, knowledge structures mediated the relationship between general cognitive ability and skill-based performance.
Knowledge acquisition and rapid protyping of an expert system: Dealing with real world problems
NASA Technical Reports Server (NTRS)
Bailey, Patrick A.; Doehr, Brett B.
1988-01-01
The knowledge engineering and rapid prototyping phases of an expert system that does fault handling for a Solid Amine, Water Desorbed CO2 removal assembly for the Environmental Control and Life Support System for space based platforms are addressed. The knowledge acquisition phase for this project was interesting because it could not follow the textbook examples. As a result of this, a variety of methods were used during the knowledge acquisition task. The use of rapid prototyping and the need for a flexible prototype suggested certain types of knowledge representation. By combining various techniques, a representative subset of faults and a method for handling those faults was achieved. The experiences should prove useful for developing future fault handling expert systems under similar constraints.
1990-12-01
data rate to the electronics would be much lower on the average and the data much "richer" in information. Intelligent use of...system bottleneck, a high data rate should be provided by I/O systems. 2. machines with intelligent storage management specially designed for logic...management information processing, surveillance sensors, intelligence data collection and handling, solid state sciences, electromagnetics, and propagation, and electronic reliability/maintainability and compatibility.
Saini, Vikram; Raghuvanshi, Saurabh; Khurana, Jitendra P.; Ahmed, Niyaz; Hasnain, Seyed E.; Tyagi, Akhilesh K.; Tyagi, Anil K.
2012-01-01
Understanding the evolutionary and genomic mechanisms responsible for turning the soil-derived saprophytic mycobacteria into lethal intracellular pathogens is a critical step towards the development of strategies for the control of mycobacterial diseases. In this context, Mycobacterium indicus pranii (MIP) is of specific interest because of its unique immunological and evolutionary significance. Evolutionarily, it is the progenitor of opportunistic pathogens belonging to M. avium complex and is endowed with features that place it between saprophytic and pathogenic species. Herein, we have sequenced the complete MIP genome to understand its unique life style, basis of immunomodulation and habitat diversification in mycobacteria. As a case of massive gene acquisitions, 50.5% of MIP open reading frames (ORFs) are laterally acquired. We show, for the first time for Mycobacterium, that MIP genome has mosaic architecture. These gene acquisitions have led to the enrichment of selected gene families critical to MIP physiology. Comparative genomic analysis indicates a higher antigenic potential of MIP imparting it a unique ability for immunomodulation. Besides, it also suggests an important role of genomic fluidity in habitat diversification within mycobacteria and provides a unique view of evolutionary divergence and putative bottlenecks that might have eventually led to intracellular survival and pathogenic attributes in mycobacteria. PMID:22965120
Knowledge Acquisition for the Onboard Planner of an Autonomous Spacecraft
NASA Technical Reports Server (NTRS)
Muscettola, Nicola; Rajan, Kanna
1997-01-01
This paper discusses the knowledge acquisition issues involved in transitioning their novel technology in to space flight software, developing the planer in the context of a large software projet and completing the work under a compressed development schedule.
Educational Software: Evaluation? No! Utility? Yes!
ERIC Educational Resources Information Center
Hofmann, Rich
1985-01-01
The utility of educational software is associated with three components: (1) type of learning (cognitive development, individually facilitated acquisition of knowledge, teacher-facilitated acquisition of knowledge, memorization); (2) type of experience (self-directed or purposive environmental experience); and (3) user perception of software…
Bottlenecks of Motion Processing during a Visual Glance: The Leaky Flask Model
Öğmen, Haluk; Ekiz, Onur; Huynh, Duong; Bedell, Harold E.; Tripathy, Srimant P.
2013-01-01
Where do the bottlenecks for information and attention lie when our visual system processes incoming stimuli? The human visual system encodes the incoming stimulus and transfers its contents into three major memory systems with increasing time scales, viz., sensory (or iconic) memory, visual short-term memory (VSTM), and long-term memory (LTM). It is commonly believed that the major bottleneck of information processing resides in VSTM. In contrast to this view, we show major bottlenecks for motion processing prior to VSTM. In the first experiment, we examined bottlenecks at the stimulus encoding stage through a partial-report technique by delivering the cue immediately at the end of the stimulus presentation. In the second experiment, we varied the cue delay to investigate sensory memory and VSTM. Performance decayed exponentially as a function of cue delay and we used the time-constant of the exponential-decay to demarcate sensory memory from VSTM. We then decomposed performance in terms of quality and quantity measures to analyze bottlenecks along these dimensions. In terms of the quality of information, two thirds to three quarters of the motion-processing bottleneck occurs in stimulus encoding rather than memory stages. In terms of the quantity of information, the motion-processing bottleneck is distributed, with the stimulus-encoding stage accounting for one third of the bottleneck. The bottleneck for the stimulus-encoding stage is dominated by the selection compared to the filtering function of attention. We also found that the filtering function of attention is operating mainly at the sensory memory stage in a specific manner, i.e., influencing only quantity and sparing quality. These results provide a novel and more complete understanding of information processing and storage bottlenecks for motion processing. PMID:24391806
Bottlenecks of motion processing during a visual glance: the leaky flask model.
Öğmen, Haluk; Ekiz, Onur; Huynh, Duong; Bedell, Harold E; Tripathy, Srimant P
2013-01-01
Where do the bottlenecks for information and attention lie when our visual system processes incoming stimuli? The human visual system encodes the incoming stimulus and transfers its contents into three major memory systems with increasing time scales, viz., sensory (or iconic) memory, visual short-term memory (VSTM), and long-term memory (LTM). It is commonly believed that the major bottleneck of information processing resides in VSTM. In contrast to this view, we show major bottlenecks for motion processing prior to VSTM. In the first experiment, we examined bottlenecks at the stimulus encoding stage through a partial-report technique by delivering the cue immediately at the end of the stimulus presentation. In the second experiment, we varied the cue delay to investigate sensory memory and VSTM. Performance decayed exponentially as a function of cue delay and we used the time-constant of the exponential-decay to demarcate sensory memory from VSTM. We then decomposed performance in terms of quality and quantity measures to analyze bottlenecks along these dimensions. In terms of the quality of information, two thirds to three quarters of the motion-processing bottleneck occurs in stimulus encoding rather than memory stages. In terms of the quantity of information, the motion-processing bottleneck is distributed, with the stimulus-encoding stage accounting for one third of the bottleneck. The bottleneck for the stimulus-encoding stage is dominated by the selection compared to the filtering function of attention. We also found that the filtering function of attention is operating mainly at the sensory memory stage in a specific manner, i.e., influencing only quantity and sparing quality. These results provide a novel and more complete understanding of information processing and storage bottlenecks for motion processing.
Bristol, Rachel M; Tucker, Rachel; Dawson, Deborah A; Horsburgh, Gavin; Prys-Jones, Robert P; Frantz, Alain C; Krupa, Andy; Shah, Nirmal J; Burke, Terry; Groombridge, Jim J
2013-09-01
Re-introduction is an important tool for recovering endangered species; however, the magnitude of genetic consequences for re-introduced populations remains largely unknown, in particular the relative impacts of historical population bottlenecks compared to those induced by conservation management. We characterize 14 microsatellite loci developed for the Seychelles paradise flycatcher and use them to quantify temporal and spatial measures of genetic variation across a 134-year time frame encompassing a historical bottleneck that reduced the species to ~28 individuals in the 1960s, through the initial stages of recovery and across a second contemporary conservation-introduction-induced bottleneck. We then evaluate the relative impacts of the two bottlenecks, and finally apply our findings to inform broader re-introduction strategy. We find a temporal trend of significant decrease in standard measures of genetic diversity across the historical bottleneck, but only a nonsignificant downward trend in number of alleles across the contemporary bottleneck. However, accounting for the different timescales of the two bottlenecks (~40 historical generations versus <1 contemporary generation), the loss of genetic diversity per generation is greater across the contemporary bottleneck. Historically, the flycatcher population was genetically structured; however, extinction on four of five islands has resulted in a homogeneous contemporary population. We conclude that severe historical bottlenecks can leave a large footprint in terms of sheer quantity of genetic diversity lost. However, severely depleted genetic diversity does not render a species immune to further genetic erosion upon re-introduction. In some cases, the loss of genetic diversity per generation can, initially at least, be greater across re-introduction-induced bottlenecks. © 2013 John Wiley & Sons Ltd.
ERIC Educational Resources Information Center
Stewart, Jeffrey; Batty, Aaron Olaf; Bovee, Nicholas
2012-01-01
Second language vocabulary acquisition has been modeled both as multidimensional in nature and as a continuum wherein the learner's knowledge of a word develops along a cline from recognition through production. In order to empirically examine and compare these models, the authors assess the degree to which the Vocabulary Knowledge Scale (VKS;…
ERIC Educational Resources Information Center
Lim, Kyu Yon
2008-01-01
The purpose of this study was to investigate the effectiveness of concept mapping strategies with different levels of generativity in terms of knowledge acquisition and knowledge representation. Also, it examined whether or not learners' self-regulated learning (SRL) skills influenced the effectiveness of concept mapping strategies with different…
ERIC Educational Resources Information Center
Albury, Nathan John
2018-01-01
Localising knowledge and dispositions helps to predict the likely success of top-down language policies. In so far as language acquisition is a pillar of language revitalisation policy, then community perspectives on learning a minority language deserve attention. This article presents the knowledge, dispositions, and ideas of around 1,300…
ERIC Educational Resources Information Center
Wijnen, Marit; Loyens, Sofie M. M.; Schaap, Lydia
2016-01-01
This study investigated the effects of problem-based learning (PBL) on knowledge acquisition and knowledge retention in a controlled experiment in a lab setting. Eighty-eight first-year psychology students were randomly assigned to either a PBL condition, a lecture condition, or a self-study condition. All participants had the opportunity to study…
Boegl, Karl; Adlassnig, Klaus-Peter; Hayashi, Yoichi; Rothenfluh, Thomas E; Leitich, Harald
2004-01-01
This paper describes the fuzzy knowledge representation framework of the medical computer consultation system MedFrame/CADIAG-IV as well as the specific knowledge acquisition techniques that have been developed to support the definition of knowledge concepts and inference rules. As in its predecessor system CADIAG-II, fuzzy medical knowledge bases are used to model the uncertainty and the vagueness of medical concepts and fuzzy logic reasoning mechanisms provide the basic inference processes. The elicitation and acquisition of medical knowledge from domain experts has often been described as the most difficult and time-consuming task in knowledge-based system development in medicine. It comes as no surprise that this is even more so when unfamiliar representations like fuzzy membership functions are to be acquired. From previous projects we have learned that a user-centered approach is mandatory in complex and ill-defined knowledge domains such as internal medicine. This paper describes the knowledge acquisition framework that has been developed in order to make easier and more accessible the three main tasks of: (a) defining medical concepts; (b) providing appropriate interpretations for patient data; and (c) constructing inferential knowledge in a fuzzy knowledge representation framework. Special emphasis is laid on the motivations for some system design and data modeling decisions. The theoretical framework has been implemented in a software package, the Knowledge Base Builder Toolkit. The conception and the design of this system reflect the need for a user-centered, intuitive, and easy-to-handle tool. First results gained from pilot studies have shown that our approach can be successfully implemented in the context of a complex fuzzy theoretical framework. As a result, this critical aspect of knowledge-based system development can be accomplished more easily.
A reusable knowledge acquisition shell: KASH
NASA Technical Reports Server (NTRS)
Westphal, Christopher; Williams, Stephen; Keech, Virginia
1991-01-01
KASH (Knowledge Acquisition SHell) is proposed to assist a knowledge engineer by providing a set of utilities for constructing knowledge acquisition sessions based on interviewing techniques. The information elicited from domain experts during the sessions is guided by a question dependency graph (QDG). The QDG defined by the knowledge engineer, consists of a series of control questions about the domain that are used to organize the knowledge of an expert. The content information supplies by the expert, in response to the questions, is represented in the form of a concept map. These maps can be constructed in a top-down or bottom-up manner by the QDG and used by KASH to generate the rules for a large class of expert system domains. Additionally, the concept maps can support the representation of temporal knowledge. The high degree of reusability encountered in the QDG and concept maps can vastly reduce the development times and costs associated with producing intelligent decision aids, training programs, and process control functions.
ESKAPE/CF: A Knowledge Acquisition Tool for Expert Systems Using Cognitive Feedback
1991-03-01
NAVAL POSTGRADUATE SCHOOL Monterey, California AD-A241 815i!1! lit 1i iill 1111 !! I 1111 ST E * ODTIC OCT22 z 99I; THESIS ESKAPE /CF: A KNOWLEDGE...11. TITLE (include Security Classification) ESKAPE /CF: A KNOWLEDGE ACQUISITION TOOL FOR EXPERT SYSTEMS USING COGNITIVE FEEDBACK (U) e PERSOIAL AUTVR(Yl...tool using Cognitive Feedback ( ESKAPE /CF), based on Lens model techniques which have demonstrated effectiveness in cap- turing policy knowledge. The
The Effects of Tailoring Knowledge Acquisition on Colorectal Cancer Screening Self-Efficacy
Jerant, Anthony; To, Patricia; Franks, Peter
2015-01-01
Interventions tailored to psychological factors such as personal and vicarious behavioral experiences can enhance behavioral self-efficacy, but are complex to develop and implement. Information seeking theory suggests tailoring acquisition of health knowledge (without concurrent psychological factor tailoring) could enhance self-efficacy, simplifying the design of tailored behavior change interventions. To begin to examine this issue, the authors conducted exploratory analyses of data from a randomized controlled trial, comparing the effects of an experimental colorectal cancer (CRC) screening intervention tailoring knowledge acquisition with the effects of a non-tailored control on CRC screening knowledge and self-efficacy in 1159 patients comprising three ethnicity/language strata (Hispanic/Spanish 23.4%, Hispanic/English 27.2%, non-Hispanic/English 49.3%) and five recruitment center strata. Adjusted for study strata, the mean post-intervention knowledge score was significantly higher in the experimental group versus control. Adjusted experimental intervention exposure (B = 0.22, 95% CI [0.14, 0.30]), pre-intervention knowledge (B = 0.11, 95% CI [0.05, 0.16]), and post-intervention knowledge (B = 0.03, 95% CI [0.01, 0.05]) were independently associated with subsequent CRC screening self-efficacy (p < .001 all associations). These exploratory findings suggest tailoring knowledge acquisition may enhance self-efficacy, with potential implications for tailored intervention design, but require confirmation in studies specifically designed to examine this issue. PMID:25928315
2013-10-08
Sciences, and Graduate School of Business & Public Policy Dr. Rene G. Rendon, Associate Professor Graduate School of Business & Public Policy...ES) Naval Postgraduate School,Graduate School of Business & Public Policy,Monterey,CA,93943 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING...report was supported by the Acquisition Research Program of the Graduate School of Business & Public Policy at the Naval Postgraduate School. To
Cardoso Coelho, Kátia; Barcellos Almeida, Maurício
2015-01-01
In this paper, we introduce a set of methodological steps for knowledge acquisition applied to the organization of biomedical information through ontologies. Those steps are tested in a real case involving Human T Cell Lymphotropic Virus (HTLV), which causes myriad infectious diseases. We hope to contribute to providing suitable knowledge representation of scientific domains.
ERIC Educational Resources Information Center
Jaros, Milan
2009-01-01
It is the outstanding intellectual challenge of our age to find ways of providing citizens with access to and competent acquisition of the new applications and systems of knowledge. The purpose of this article is twofold. First, it is to justify at the conceptual level that we are facing an unprecedented shift in the way knowledge is generated and…
ERIC Educational Resources Information Center
Alqarni, Ibrahim R.
2017-01-01
This study investigates the impact that study in Australia has on the lexical knowledge of Saudi Arabian students. It focuses on: 1) the effects that the length of study in Australia has on the acquisition of lexical collocations, as reflected by lexical knowledge tests, and 2) whether there is a significant gender difference in the acquisition of…
ERIC Educational Resources Information Center
Buchholtz, Nils Frederik
2017-01-01
This paper reports on a longitudinal mixed methods evaluation study on the acquisition and development of mathematical pedagogical content knowledge (MPCK) of future teachers at several German universities. The study is a German supplementary study to the international comparative TEDS-M 2008 study. Besides the pedagogical content knowledge that…
ERIC Educational Resources Information Center
Wilde, Matthias; Hubmann, Jona Samuel; Lorenzen, Simone; Meyer, Annika; Randler, Christoph
2012-01-01
The aim of this study was to evaluate the effects of living animals on pupils' intrinsic motivation and knowledge. Various studies from the late 1970s and 1980s stress the high effectiveness of authentic learning experiences in pupils' knowledge acquisition. However, there are only few current empirical studies on this topic. The research question…
Genetic diversity and fitness in black-footed ferrets before and during a bottleneck.
Wisely, S M; Buskirk, S W; Fleming, M A; McDonald, D B; Ostrander, E A
2002-01-01
The black-footed ferret (Mustela nigripes) is an endangered North American carnivore that underwent a well-documented population bottleneck in the mid-1980s. To better understand the effects of a bottleneck on a free-ranging carnivore population, we used 24 microsatellite loci to compare genetic diversity before versus during the bottleneck, and compare the last wild population to two historical populations. We also compared genetic diversity in black-footed ferrets to that of two sibling species, the steppe polecat (Mustela eversmanni) and the European polecat (Mustela putorius). Black-footed ferrets during the bottleneck had less genetic diversity than steppe polecats. The three black-footed ferret populations were well differentiated (F(ST) = 0.57 +/- 0.15; mean +/- SE). We attributed the decrease in genetic diversity in black-footed ferrets to localized extinction of these genetically distinct subpopulations and to the bottleneck in the surviving subpopulation. Although genetic diversity decreased, female fecundity and juvenile survival were not affected by the population bottleneck.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-18
... Acquisition, Language Enhancement, and Academic Achievement for Limited English Proficient Students; Overview... to provide instruction that accelerates ELs' acquisition of language, literacy, and content knowledge.... Rosalinda Barrera, Assistant Deputy Secretary and Director for English Language Acquisition, Language...
Regridding reconstruction algorithm for real-time tomographic imaging
Marone, F.; Stampanoni, M.
2012-01-01
Sub-second temporal-resolution tomographic microscopy is becoming a reality at third-generation synchrotron sources. Efficient data handling and post-processing is, however, difficult when the data rates are close to 10 GB s−1. This bottleneck still hinders exploitation of the full potential inherent in the ultrafast acquisition speed. In this paper the fast reconstruction algorithm gridrec, highly optimized for conventional CPU technology, is presented. It is shown that gridrec is a valuable alternative to standard filtered back-projection routines, despite being based on the Fourier transform method. In fact, the regridding procedure used for resampling the Fourier space from polar to Cartesian coordinates couples excellent performance with negligible accuracy degradation. The stronger dependence of the observed signal-to-noise ratio for gridrec reconstructions on the number of angular views makes the presented algorithm even superior to filtered back-projection when the tomographic problem is well sampled. Gridrec not only guarantees high-quality results but it provides up to 20-fold performance increase, making real-time monitoring of the sub-second acquisition process a reality. PMID:23093766
Research of Litchi Diseases Diagnosis Expertsystem Based on Rbr and Cbr
NASA Astrophysics Data System (ADS)
Xu, Bing; Liu, Liqun
To conquer the bottleneck problems existing in the traditional rule-based reasoning diseases diagnosis system, such as low reasoning efficiency and lack of flexibility, etc.. It researched the integrated case-based reasoning (CBR) and rule-based reasoning (RBR) technology, and put forward a litchi diseases diagnosis expert system (LDDES) with integrated reasoning method. The method use data mining and knowledge obtaining technology to establish knowledge base and case library. It adopt rules to instruct the retrieval and matching for CBR, and use association rule and decision trees algorithm to calculate case similarity.The experiment shows that the method can increase the system's flexibility and reasoning ability, and improve the accuracy of litchi diseases diagnosis.
Knowledge acquisition for temporal abstraction.
Stein, A; Musen, M A; Shahar, Y
1996-01-01
Temporal abstraction is the task of detecting relevant patterns in data over time. The knowledge-based temporal-abstraction method uses knowledge about a clinical domain's contexts, external events, and parameters to create meaningful interval-based abstractions from raw time-stamped clinical data. In this paper, we describe the acquisition and maintenance of domain-specific temporal-abstraction knowledge. Using the PROTEGE-II framework, we have designed a graphical tool for acquiring temporal knowledge directly from expert physicians, maintaining the knowledge in a sharable form, and converting the knowledge into a suitable format for use by an appropriate problem-solving method. In initial tests, the tool offered significant gains in our ability to rapidly acquire temporal knowledge and to use that knowledge to perform automated temporal reasoning.
Traffic behavior at freeway bottlenecks.
DOT National Transportation Integrated Search
2014-09-01
This study examines traffic behavior in the vicinity of a freeway bottleneck, revisiting commonly held : assumptions and uncovering systematic biases that likely have distorted empirical studies of bottleneck : formation, capacity drop, and the funda...
Griffis, Joseph C; Nenert, Rodolphe; Allendorfer, Jane B; Szaflarski, Jerzy P
2017-01-01
Damage to the white matter underlying the left posterior temporal lobe leads to deficits in multiple language functions. The posterior temporal white matter may correspond to a bottleneck where both dorsal and ventral language pathways are vulnerable to simultaneous damage. Damage to a second putative white matter bottleneck in the left deep prefrontal white matter involving projections associated with ventral language pathways and thalamo-cortical projections has recently been proposed as a source of semantic deficits after stroke. Here, we first used white matter atlases to identify the previously described white matter bottlenecks in the posterior temporal and deep prefrontal white matter. We then assessed the effects of damage to each region on measures of verbal fluency, picture naming, and auditory semantic decision-making in 43 chronic left hemispheric stroke patients. Damage to the posterior temporal bottleneck predicted deficits on all tasks, while damage to the anterior bottleneck only significantly predicted deficits in verbal fluency. Importantly, the effects of damage to the bottleneck regions were not attributable to lesion volume, lesion loads on the tracts traversing the bottlenecks, or damage to nearby cortical language areas. Multivariate lesion-symptom mapping revealed additional lesion predictors of deficits. Post-hoc fiber tracking of the peak white matter lesion predictors using a publicly available tractography atlas revealed evidence consistent with the results of the bottleneck analyses. Together, our results provide support for the proposal that spatially specific white matter damage affecting bottleneck regions, particularly in the posterior temporal lobe, contributes to chronic language deficits after left hemispheric stroke. This may reflect the simultaneous disruption of signaling in dorsal and ventral language processing streams.
Kassa, Mulualem T; Penmetsa, R Varma; Carrasquilla-Garcia, Noelia; Sarma, Birinchi K; Datta, Subhojit; Upadhyaya, Hari D; Varshney, Rajeev K; von Wettberg, Eric J B; Cook, Douglas R
2012-01-01
Pigeonpea (Cajanus cajan) is an annual or short-lived perennial food legume of acute regional importance, providing significant protein to the human diet in less developed regions of Asia and Africa. Due to its narrow genetic base, pigeonpea improvement is increasingly reliant on introgression of valuable traits from wild forms, a practice that would benefit from knowledge of its domestication history and relationships to wild species. Here we use 752 single nucleotide polymorphisms (SNPs) derived from 670 low copy orthologous genes to clarify the evolutionary history of pigeonpea (79 accessions) and its wild relatives (31 accessions). We identified three well-supported lineages that are geographically clustered and congruent with previous nuclear and plastid sequence-based phylogenies. Among all species analyzed Cajanus cajanifolius is the most probable progenitor of cultivated pigeonpea. Multiple lines of evidence suggest recent gene flow between cultivated and non-cultivated forms, as well as historical gene flow between diverged but sympatric species. Evidence supports that primary domestication occurred in India, with a second and more recent nested population bottleneck focused in tropical regions that is the likely consequence of pigeonpea breeding. We find abundant allelic variation and genetic diversity among the wild relatives, with the exception of wild species from Australia for which we report a third bottleneck unrelated to domestication within India. Domesticated C. cajan possess 75% less allelic diversity than the progenitor clade of wild Indian species, indicating a severe "domestication bottleneck" during pigeonpea domestication.
A Preliminary Analysis of the Theoretical Parameters of Organizaational Learning.
1995-09-01
PARAMETERS OF ORGANIZATIONAL LEARNING THESIS Presented to the Faculty of the Graduate School of Logistics and Acquisition Management of the Air...Organizational Learning Parameters in the Knowledge Acquisition Category 2~™ 2-3. Organizational Learning Parameters in the Information Distribution Category...Learning Refined Scale 4-94 4-145. Composition of Refined Scale 4 Knowledge Flow 4-95 4-146. Cronbach’s Alpha Statistics for the Complete Knowledge Flow
Continuous stacking computational approach based automated microscope slide scanner
NASA Astrophysics Data System (ADS)
Murali, Swetha; Adhikari, Jayesh Vasudeva; Jagannadh, Veerendra Kalyan; Gorthi, Sai Siva
2018-02-01
Cost-effective and automated acquisition of whole slide images is a bottleneck for wide-scale deployment of digital pathology. In this article, a computation augmented approach for the development of an automated microscope slide scanner is presented. The realization of a prototype device built using inexpensive off-the-shelf optical components and motors is detailed. The applicability of the developed prototype to clinical diagnostic testing is demonstrated by generating good quality digital images of malaria-infected blood smears. Further, the acquired slide images have been processed to identify and count the number of malaria-infected red blood cells and thereby perform quantitative parasitemia level estimation. The presented prototype would enable cost-effective deployment of slide-based cyto-diagnostic testing in endemic areas.
The Use of Computer-Based Videogames in Knowledge Acquisition and Retention.
ERIC Educational Resources Information Center
Ricci, Katrina E.
1994-01-01
Research conducted at the Naval Training Systems Center in Orlando, Florida, investigated the acquisition and retention of basic knowledge with subject matter presented in the forms of text, test, and game. Results are discussed in terms of the effectiveness of computer-based games for military training. (Author/AEF)
ERIC Educational Resources Information Center
Dohn, Nina Bonderup
2016-01-01
This article aims to appraise insights from participationist approaches to learning for understanding students' knowledge acquisition. The first part explicates the concepts of positioning, recognition, and identity through presenting a common ground for participationists and discussing different views on (a) the relationship between learning the…
Linking Parser Development to Acquisition of Syntactic Knowledge
ERIC Educational Resources Information Center
Omaki, Akira; Lidz, Jeffrey
2015-01-01
Traditionally, acquisition of syntactic knowledge and the development of sentence comprehension behaviors have been treated as separate disciplines. This article reviews a growing body of work on the development of incremental sentence comprehension mechanisms and discusses how a better understanding of the developing parser can shed light on two…
The Perceived Effects of Flipped Teaching on Knowledge Acquisition
ERIC Educational Resources Information Center
Newman, Galen; Kim, Jun-Hyun; Lee, Ryun Jung; Brown, Brandy A.; Huston, Sharon
2016-01-01
Increased demands for technological integration in higher education have resulted in new forms of course instruction. Under a flipped approach, students learn course materials outside the classroom while active learning methods are employed inside. This study focuses on the perceived effects of flipped instruction on knowledge acquisition in…
Knowledge Organization and the Acquisition of Procedural Expertise.
1987-10-01
NO NO ACCESSION NO 11i TITLE (InCludf S#cufltY Cissjf)CAtl~on) KOWLEDGE ORGANIZATION AND THE ACQUISITION OF PROCEDURAL EXPERTISE 12 PERSONAL AUTIR...explanatory material strongly influences the knowledge representation of the learner which, in turn, exerts a powerful influence over the degree to which
Pragmatic User Model Implementation in an Intelligent Help System.
ERIC Educational Resources Information Center
Fernandez-Manjon, Baltasar; Fernandez-Valmayor, Alfredo; Fernandez-Chamizo, Carmen
1998-01-01
Describes Aran, a knowledge-based system designed to help users deal with problems related to Unix operation. Highlights include adaptation to the individual user; user modeling knowledge; stereotypes; content of the individual user model; instantiation, acquisition, and maintenance of the individual model; dynamic acquisition of objective and…
Implicit Trust in a Data Model
2011-10-01
model, interfacing will be easier 8. This aspect is usually not a concern for operators. 8. Interfacing can account for between 25-70% of the cost of...32 6.7.3 Flexibility . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 6.7.4 Cost of Knowledge Acquisition...51 8.5.4 Cost of Knowledge Acquisition . . . . . . . . . . . . . . . . . . 52 8.6 Reputation
Knowledge Acquisition by Hypervideo Design: An Instructional Program for University Courses
ERIC Educational Resources Information Center
Stahl, Elmar; Finke, Matthias; Zahn, Carmen
2006-01-01
This article presents an instructional program for collaborative construction of hypervideos. The instructional program integrates (a) hypervideo technology development, (b) assumptions on learning with hypervideo systems, and (c) the application of research on knowledge acquisition by writing texts or hypertexts to hypervideos. The aim of the…
Sequencing in SLA: Phonological Memory, Chunking, and Points of Order.
ERIC Educational Resources Information Center
Ellis, Nick C.
1996-01-01
Argues that much of language acquisition is sequence learning and that the resultant long-term knowledge base of language sequences serves as the database for grammar acquisition. The article also proposes mechanisms to analyze sequence information that result in knowledge of underlying grammar. (184 references) (Author/CK)
Williams, Betsy W; Kessler, Harold A; Williams, Michael V
2015-01-01
The relationship among an individual's sense of self-efficacy, motivation to change, barriers to change, and the implementation of improvement programs has been reported. This research reports the relationship among self-efficacy, motivation to change, and the acquisition of knowledge in a continuing medical education (CME) activity. The measure of individual sense of self-efficacy was a 4-item scale. The measure of motivation was a 6-item scale following on the work of Prochaska and colleagues. The knowledge acquisition was measured in a simple post measure. The participants were enrolled in a CME activity focused on HIV. The CME activities had a significant effect on knowledge. Preliminary analysis demonstrates a relationship among the self-efficacy measure, the motivation to change measure, and global intent to change. Specifically, as reported earlier, the sense of efficacy in effecting change in the practice environment is predictive of a high level of motivation to change that, in turn, is predictive of formation of intent to change practice patterns. Interestingly, there were also relationships among the self-efficacy measure, the motivation to change measure, and knowledge acquisition. Finally, as expected, there was a significant relationship between knowledge and intent to change practice. Further inspection of the motivation to change construct suggests that it mediates the self-efficacy constructs' effect on intent as well as its effect on knowledge acquisition. This new finding suggests that the proximal construct motivation completely masks an important underlying causal relationship that appears to contribute to practice change as well as learning following CME-self-efficacy. © 2015 The Alliance for Continuing Education in the Health Professions, the Society for Academic Continuing Medical Education, and the Council on Continuing Medical Education, Association for Hospital Medical Education.
Tu, S W; Eriksson, H; Gennari, J H; Shahar, Y; Musen, M A
1995-06-01
PROTEGE-II is a suite of tools and a methodology for building knowledge-based systems and domain-specific knowledge-acquisition tools. In this paper, we show how PROTEGE-II can be applied to the task of providing protocol-based decision support in the domain of treating HIV-infected patients. To apply PROTEGE-II, (1) we construct a decomposable problem-solving method called episodic skeletal-plan refinement, (2) we build an application ontology that consists of the terms and relations in the domain, and of method-specific distinctions not already captured in the domain terms, and (3) we specify mapping relations that link terms from the application ontology to the domain-independent terms used in the problem-solving method. From the application ontology, we automatically generate a domain-specific knowledge-acquisition tool that is custom-tailored for the application. The knowledge-acquisition tool is used for the creation and maintenance of domain knowledge used by the problem-solving method. The general goal of the PROTEGE-II approach is to produce systems and components that are reusable and easily maintained. This is the rationale for constructing ontologies and problem-solving methods that can be composed from a set of smaller-grained methods and mechanisms. This is also why we tightly couple the knowledge-acquisition tools to the application ontology that specifies the domain terms used in the problem-solving systems. Although our evaluation is still preliminary, for the application task of providing protocol-based decision support, we show that these goals of reusability and easy maintenance can be achieved. We discuss design decisions and the tradeoffs that have to be made in the development of the system.
Factors Associated with Medical Knowledge Acquisition During Internal Medicine Residency
Zeger, Scott L.; Kolars, Joseph C.
2007-01-01
BACKGROUND Knowledge acquisition is a goal of residency and is measurable by in-training exams. Little is known about factors associated with medical knowledge acquisition. OBJECTIVE To examine associations of learning habits on medical knowledge acquisition. DESIGN, PARTICIPANTS Cohort study of all 195 residents who took the Internal Medicine In-Training Examination (IM-ITE) 421 times over 4 years while enrolled in the Internal Medicine Residency, Mayo Clinic, Rochester, MN. MEASUREMENTS Score (percent questions correct) on the IM-ITE adjusted for variables known or hypothesized to be associated with score using a random effects model. RESULTS When adjusting for demographic, training, and prior achievement variables, yearly advancement within residency was associated with an IM-ITE score increase of 5.1% per year (95%CI 4.1%, 6.2%; p < .001). In the year before examination, comparable increases in IM-ITE score were associated with attendance at two curricular conferences per week, score increase of 3.9% (95%CI 2.1%, 5.7%; p < .001), or self-directed reading of an electronic knowledge resource 20 minutes each day, score increase of 4.5% (95%CI 1.2%, 7.8%; p = .008). Other factors significantly associated with IM-ITE performance included: age at start of residency, score decrease per year of increasing age, −0.2% (95%CI −0.36%, −0.042%; p = .01), and graduation from a US medical school, score decrease compared to international medical school graduation, −3.4% (95%CI −6.5%, −0.36%; p = .03). CONCLUSIONS Conference attendance and self-directed reading of an electronic knowledge resource had statistically and educationally significant independent associations with knowledge acquisition that were comparable to the benefit of a year in residency training. PMID:17468889
Sriyudthsak, Kansuporn; Shiraishi, Fumihide
2010-11-01
A number of recent research studies have focused on theoretical and experimental investigation of a bottleneck in a metabolic reaction network. However, there is no study on how the bottleneck affects the performance of a fermentation process when a product is highly toxic and remarkably influences the growth and death of cells. The present work therefore studies the effect of bottleneck on product concentrations under different product toxicity conditions. A generalized bottleneck model in a fed-batch fermentation is constructed including both the bottleneck and the product influences on cell growth and death. The simulation result reveals that when the toxic product strongly influences the cell growth and death, the final product concentration is hardly changed even if the bottleneck is removed, whereas it is markedly changed by the degree of product toxicity. The performance of an ethanol fermentation process is also discussed as a case example to validate this result. In conclusion, when the product is highly toxic, one cannot expect a significant increase in the final product concentration even if removing the bottleneck; rather, it may be more effective to somehow protect the cells so that they can continuously produce the product. Copyright © 2010 Elsevier Inc. All rights reserved.
2014-04-30
PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Postgraduate School,Graduate School of Business & Public Policy,555 Dyer Rd,Monterey,CA,93943 8...pÅÜççä= The research presented in this report was supported by the Acquisition Research Program of the Graduate School of Business & Public Policy at...big business . The U.S. Department of Defense (DoD) alone routinely executes 12-figure budgets for research, development, procurement, and support of
Jurkowski, Susanne; Hänze, Martin
2015-09-01
Transactive communication means referring to and building on a learning partner's idea, by, for example, extending the partner's idea or interlinking the partner's idea with an idea of one's own. This transforms the partner's idea into a more elaborate one. Previous research found a positive relationship between students' transactive communication and their learning results when working in small groups. To increase the benefits of cooperation, we developed and tested a module for training students in transactive communication. We assumed that this training would enhance students' transactive communication and also increase their knowledge acquisition during cooperative learning. Further, we distinguished between an actor's transactive communication and a learning partner's transactive communication and expected both to be positively associated with an actor's knowledge acquisition. Participants were 80 university students. In an experiment with pre- and post-test measurements, transactive communication was measured by coding students' communication in a cooperative learning situation before training and in another cooperative learning situation after training. For the post-test cooperative learning situation, knowledge was pre-tested and post-tested. Trained students outperformed controls in transactive communication and in knowledge acquisition. Positive training effects on actors' knowledge acquisition were partially mediated by the improved actors' transactive communication. Moreover, actors' knowledge acquisition was positively influenced by learning partners' transactive communication. Results show a meaningful increase in the benefits of cooperation through the training in transactive communication. Furthermore, findings indicate that students benefit from both elaborating on their partner's ideas and having their own ideas elaborated on. © 2015 The British Psychological Society.
Task analysis of intersection driving scenarios : information processing bottlenecks
DOT National Transportation Integrated Search
2006-08-01
The purpose of this report is to identify the information processing bottlenecks that drivers face in specific intersection driving scenarios. These bottlenecks represent situations in which drivers may become 'overloaded' by driving demands, which c...
NASA Technical Reports Server (NTRS)
Lien, Mei-Ching; McCann, Robert S.; Ruthruff, Eric; Proctor, Robert W.
2005-01-01
The present study examined whether the central bottleneck, assumed to be primarily responsible for the psychological refractory period (PRP) effect, is intact, bypassed, or shifted in locus with ideomotor (IM)-compatible tasks. In 4 experiments, factorial combinations of IM- and non-IM-compatible tasks were used for Task 1 and Task 2. All experiments showed substantial PRP effects, with a strong dependency between Task 1 and Task 2 response times. These findings, along with model-based simulations, indicate that the processing bottleneck was not bypassed, even with two IM-compatible tasks. Nevertheless, systematic changes in the PRP and correspondence effects across experiments suggest that IM compatibility shifted the locus of the bottleneck. The findings favor an engage-bottleneck-later hypothesis, whereby parallelism between tasks occurs deeper into the processing stream for IM- than for non-IM-compatible tasks, without the bottleneck being actually eliminated.
2013-01-01
Background Demographic bottlenecks can severely reduce the genetic variation of a population or a species. Establishing whether low genetic variation is caused by a bottleneck or a constantly low effective number of individuals is important to understand a species’ ecology and evolution, and it has implications for conservation management. Recent studies have evaluated the power of several statistical methods developed to identify bottlenecks. However, the false positive rate, i.e. the rate with which a bottleneck signal is misidentified in demographically stable populations, has received little attention. We analyse this type of error (type I) in forward computer simulations of stable populations having greater than Poisson variance in reproductive success (i.e., variance in family sizes). The assumption of Poisson variance underlies bottleneck tests, yet it is commonly violated in species with high fecundity. Results With large variance in reproductive success (Vk ≥ 40, corresponding to a ratio between effective and census size smaller than 0.1), tests based on allele frequencies, allelic sizes, and DNA sequence polymorphisms (heterozygosity excess, M-ratio, and Tajima’s D test) tend to show erroneous signals of a bottleneck. Similarly, strong evidence of population decline is erroneously detected when ancestral and current population sizes are estimated with the model based method MSVAR. Conclusions Our results suggest caution when interpreting the results of bottleneck tests in species showing high variance in reproductive success. Particularly in species with high fecundity, computer simulations are recommended to confirm the occurrence of a population bottleneck. PMID:24131797
A Proposed Model of Jazz Theory Knowledge Acquisition
ERIC Educational Resources Information Center
Ciorba, Charles R.; Russell, Brian E.
2014-01-01
The purpose of this study was to test a hypothesized model that proposes a causal relationship between motivation and academic achievement on the acquisition of jazz theory knowledge. A reliability analysis of the latent variables ranged from 0.92 to 0.94. Confirmatory factor analyses of the motivation (standardized root mean square residual…
ERIC Educational Resources Information Center
Hare, Molly K.; Graber, Kim C.
2007-01-01
Grounded within constructivist theory, the purpose of this investigation was to investigate knowledge acquisition and developing conceptions of high school-aged students during a unit of instruction in badminton. Six different qualitative methods were utilized: (a) observations, (b) formal interviews, (c) informal interviews, (d) think aloud…
Knowledge acquisition for a simple expert controller
NASA Technical Reports Server (NTRS)
Bieker, B.
1987-01-01
A method is presented for process control which has the properties of being incremental, cyclic and top-down. It is described on the basis of the development of an expert controller for a simple, but nonlinear control route. A quality comparison between expert controller and process operator shows the ability of the method for knowledge acquisition.
ERIC Educational Resources Information Center
Thomas, Jennifer D. E.
2007-01-01
This paper investigates students' perceptions of their acquisition of knowledge management skills, namely thinking and team-building skills, resulting from the integration of various resources and technologies into an entirely team-based, online upper level distributed computing (DC) information systems (IS) course. Results seem to indicate that…
ERIC Educational Resources Information Center
Zheng, Robert
2010-01-01
This study focuses on the effects of situated learning on students' knowledge acquisition by investigating the influence of individual differences in such learning. Seventy-nine graduates were recruited from an educational department and were assigned to situated learning and traditional learning based on a randomized block design. Results…
Examining Incidental Vocabulary Acquisition by Person-and Item-Level Factors in Secondary Students
ERIC Educational Resources Information Center
Cooper, Jennifer LeeAnn
2016-01-01
Vocabulary knowledge is central to the process of reading comprehension (Cromely & Azevedo, 2007; Stahl & Nagy, 2005; Stanovich, 1986). The majority of our vocabulary knowledge is postulated to come from the process of incidental vocabulary acquisition (IVA) while reading (Nagy & Anderson, 1984). Prior studies have estimated an average…
Adaptive Search through Constraint Violations
1990-01-01
procedural) knowledge? Different methodologies are used to investigate these questions: Psychological experiments, computer simulations, historical studies...learns control knowledge through adaptive search. Unlike most other psychological models of skill acquisition, HS is a model of analytical, or...Newzll, 1986; VanLehn, in press). Psychological models of skill acquisition employ different problem solving mechanisms (forward search, backward
48 CFR 52.222-18 - Certification Regarding Knowledge of Child Labor for Listed End Products.
Code of Federal Regulations, 2010 CFR
2010-10-01
... for Listed End Products. As prescribed in 22.1505(a), insert the following provision: Certification... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Certification Regarding Knowledge of Child Labor for Listed End Products. 52.222-18 Section 52.222-18 Federal Acquisition...
ERIC Educational Resources Information Center
IRIS Center, 2014
2014-01-01
This report presents two studies that demonstrate superior performance of college students after use of free, online instructional Modules, produced by the IRIS Center. When compared to traditional teacher education methods, IRIS Modules yield better outcomes in terms of knowledge acquisition, application skills, and confidence in the use of…
Information/Knowledge Acquisition Methods for Decision Support Systems and Expert Systems.
ERIC Educational Resources Information Center
Yang, Heng-Li
1995-01-01
Compares information requirement-elicitation (IRE) methods for decision support systems (DSS) with knowledge acquisition (KA) methods for expert systems (ES) development. The definition and architectures of ES and DSS are compared and the systems' development cycles and IRE/KA methods are discussed. Differences are noted between ES and DSS…
Supplemental knowledge acquisition through external product interface for CLIPS
NASA Technical Reports Server (NTRS)
Saito, Tim; Ebaud, Stephen; Loftin, Bowen R.
1990-01-01
Traditionally, the acquisition of knowledge for expert systems consisted of the interview process with the domain or subject matter expert (SME), observation of domain environment, and information gathering and research which constituted a direct form of knowledge acquisition (KA). The knowledge engineer would be responsible for accumulating pertinent information and/or knowledge from the SME(s) for input into the appropriate expert system development tool. The direct KA process may (or may not) have included forms of data or documentation to incorporate from the SME's surroundings. The differentiation between direct KA and supplemental KA (indirect) would be the difference in the use of data. In acquiring supplemental knowledge, the knowledge engineer would access other types of evidence (manuals, documents, data files, spreadsheets, etc.) that would support the reasoning or premises of the SME. When an expert makes a decision in a particular task, one tool that may have been used to justify a recommendation, would have been a spreadsheet total or column figure. Locating specific decision points from that data within the SME's framework would constitute supplemental KA. Data used for a specific purpose in one system or environment would be used as supplemental knowledge for another, specifically a CLIPS project.
Data Streaming for Metabolomics: Accelerating Data Processing and Analysis from Days to Minutes
2016-01-01
The speed and throughput of analytical platforms has been a driving force in recent years in the “omics” technologies and while great strides have been accomplished in both chromatography and mass spectrometry, data analysis times have not benefited at the same pace. Even though personal computers have become more powerful, data transfer times still represent a bottleneck in data processing because of the increasingly complex data files and studies with a greater number of samples. To meet the demand of analyzing hundreds to thousands of samples within a given experiment, we have developed a data streaming platform, XCMS Stream, which capitalizes on the acquisition time to compress and stream recently acquired data files to data processing servers, mimicking just-in-time production strategies from the manufacturing industry. The utility of this XCMS Online-based technology is demonstrated here in the analysis of T cell metabolism and other large-scale metabolomic studies. A large scale example on a 1000 sample data set demonstrated a 10 000-fold time savings, reducing data analysis time from days to minutes. Further, XCMS Stream has the capability to increase the efficiency of downstream biochemical dependent data acquisition (BDDA) analysis by initiating data conversion and data processing on subsets of data acquired, expanding its application beyond data transfer to smart preliminary data decision-making prior to full acquisition. PMID:27983788
Data streaming for metabolomics: Accelerating data processing and analysis from days to minutes
Montenegro-Burke, J. Rafael; Aisporna, Aries E.; Benton, H. Paul; ...
2016-12-16
The speed and throughput of analytical platforms has been a driving force in recent years in the “omics” technologies and while great strides have been accomplished in both chromatography and mass spectrometry, data analysis times have not benefited at the same pace. Even though personal computers have become more powerful, data transfer times still represent a bottleneck in data processing because of the increasingly complex data files and studies with a greater number of samples. To meet the demand of analyzing hundreds to thousands of samples within a given experiment, we have developed a data streaming platform, XCMS Stream, whichmore » capitalizes on the acquisition time to compress and stream recently acquired data files to data processing servers, mimicking just-in-time production strategies from the manufacturing industry. The utility of this XCMS Online-based technology is demonstrated here in the analysis of T cell metabolism and other large-scale metabolomic studies. A large scale example on a 1000 sample data set demonstrated a 10 000-fold time savings, reducing data analysis time from days to minutes. Here, XCMS Stream has the capability to increase the efficiency of downstream biochemical dependent data acquisition (BDDA) analysis by initiating data conversion and data processing on subsets of data acquired, expanding its application beyond data transfer to smart preliminary data decision-making prior to full acquisition.« less
Data Streaming for Metabolomics: Accelerating Data Processing and Analysis from Days to Minutes.
Montenegro-Burke, J Rafael; Aisporna, Aries E; Benton, H Paul; Rinehart, Duane; Fang, Mingliang; Huan, Tao; Warth, Benedikt; Forsberg, Erica; Abe, Brian T; Ivanisevic, Julijana; Wolan, Dennis W; Teyton, Luc; Lairson, Luke; Siuzdak, Gary
2017-01-17
The speed and throughput of analytical platforms has been a driving force in recent years in the "omics" technologies and while great strides have been accomplished in both chromatography and mass spectrometry, data analysis times have not benefited at the same pace. Even though personal computers have become more powerful, data transfer times still represent a bottleneck in data processing because of the increasingly complex data files and studies with a greater number of samples. To meet the demand of analyzing hundreds to thousands of samples within a given experiment, we have developed a data streaming platform, XCMS Stream, which capitalizes on the acquisition time to compress and stream recently acquired data files to data processing servers, mimicking just-in-time production strategies from the manufacturing industry. The utility of this XCMS Online-based technology is demonstrated here in the analysis of T cell metabolism and other large-scale metabolomic studies. A large scale example on a 1000 sample data set demonstrated a 10 000-fold time savings, reducing data analysis time from days to minutes. Further, XCMS Stream has the capability to increase the efficiency of downstream biochemical dependent data acquisition (BDDA) analysis by initiating data conversion and data processing on subsets of data acquired, expanding its application beyond data transfer to smart preliminary data decision-making prior to full acquisition.
Kangaroo mother care: a multi-country analysis of health system bottlenecks and potential solutions.
Vesel, Linda; Bergh, Anne-Marie; Kerber, Kate J; Valsangkar, Bina; Mazia, Goldy; Moxon, Sarah G; Blencowe, Hannah; Darmstadt, Gary L; de Graft Johnson, Joseph; Dickson, Kim E; Ruiz Peláez, Juan; von Xylander, Severin; Lawn, Joy E
2015-01-01
Preterm birth is now the leading cause of under-five child deaths worldwide with one million direct deaths plus approximately another million where preterm is a risk factor for neonatal deaths due to other causes. There is strong evidence that kangaroo mother care (KMC) reduces mortality among babies with birth weight <2000 g (mostly preterm). KMC involves continuous skin-to-skin contact, breastfeeding support, and promotion of early hospital discharge with follow-up. The World Health Organization has endorsed KMC for stabilised newborns in health facilities in both high-income and low-resource settings. The objectives of this paper are to: (1) use a 12-country analysis to explore health system bottlenecks affecting the scale-up of KMC; (2) propose solutions to the most significant bottlenecks; and (3) outline priority actions for scale-up. The bottleneck analysis tool was applied in 12 countries in Africa and Asia as part of the Every Newborn Action Plan process. Country workshops involved technical experts to complete the survey tool, which is designed to synthesise and grade health system "bottlenecks", factors that hinder the scale-up, of maternal-newborn intervention packages. We used quantitative and qualitative methods to analyse the bottleneck data, combined with literature review, to present priority bottlenecks and actions relevant to different health system building blocks for KMC. Marked differences were found in the perceived severity of health system bottlenecks between Asian and African countries, with the former reporting more significant or very major bottlenecks for KMC with respect to all the health system building blocks. Community ownership and health financing bottlenecks were significant or very major bottlenecks for KMC in both low and high mortality contexts, particularly in South Asia. Significant bottlenecks were also reported for leadership and governance and health workforce building blocks. There are at least a dozen countries worldwide with national KMC programmes, and we identify three pathways to scale: (1) champion-led; (2) project-initiated; and (3) health systems designed. The combination of all three pathways may lead to more rapid scale-up. KMC has the potential to save lives, and change the face of facility-based newborn care, whilst empowering women to care for their preterm newborns.
Kangaroo mother care: a multi-country analysis of health system bottlenecks and potential solutions
2015-01-01
Background Preterm birth is now the leading cause of under-five child deaths worldwide with one million direct deaths plus approximately another million where preterm is a risk factor for neonatal deaths due to other causes. There is strong evidence that kangaroo mother care (KMC) reduces mortality among babies with birth weight <2000 g (mostly preterm). KMC involves continuous skin-to-skin contact, breastfeeding support, and promotion of early hospital discharge with follow-up. The World Health Organization has endorsed KMC for stabilised newborns in health facilities in both high-income and low-resource settings. The objectives of this paper are to: (1) use a 12-country analysis to explore health system bottlenecks affecting the scale-up of KMC; (2) propose solutions to the most significant bottlenecks; and (3) outline priority actions for scale-up. Methods The bottleneck analysis tool was applied in 12 countries in Africa and Asia as part of the Every Newborn Action Plan process. Country workshops involved technical experts to complete the survey tool, which is designed to synthesise and grade health system "bottlenecks", factors that hinder the scale-up, of maternal-newborn intervention packages. We used quantitative and qualitative methods to analyse the bottleneck data, combined with literature review, to present priority bottlenecks and actions relevant to different health system building blocks for KMC. Results Marked differences were found in the perceived severity of health system bottlenecks between Asian and African countries, with the former reporting more significant or very major bottlenecks for KMC with respect to all the health system building blocks. Community ownership and health financing bottlenecks were significant or very major bottlenecks for KMC in both low and high mortality contexts, particularly in South Asia. Significant bottlenecks were also reported for leadership and governance and health workforce building blocks. Conclusions There are at least a dozen countries worldwide with national KMC programmes, and we identify three pathways to scale: (1) champion-led; (2) project-initiated; and (3) health systems designed. The combination of all three pathways may lead to more rapid scale-up. KMC has the potential to save lives, and change the face of facility-based newborn care, whilst empowering women to care for their preterm newborns. PMID:26391115
A design for a ground-based data management system
NASA Technical Reports Server (NTRS)
Lambird, Barbara A.; Lavine, David
1988-01-01
An initial design for a ground-based data management system which includes intelligent data abstraction and cataloging is described. The large quantity of data on some current and future NASA missions leads to significant problems in providing scientists with quick access to relevant data. Human screening of data for potential relevance to a particular study is time-consuming and costly. Intelligent databases can provide automatic screening when given relevent scientific parameters and constraints. The data management system would provide, at a minimum, information of availability of the range of data, the type available, specific time periods covered together with data quality information, and related sources of data. The system would inform the user about the primary types of screening, analysis, and methods of presentation available to the user. The system would then aid the user with performing the desired tasks, in such a way that the user need only specify the scientific parameters and objectives, and not worry about specific details for running a particular program. The design contains modules for data abstraction, catalog plan abstraction, a user-friendly interface, and expert systems for data handling, data evaluation, and application analysis. The emphasis is on developing general facilities for data representation, description, analysis, and presentation that will be easily used by scientists directly, thus bypassing the knowledge acquisition bottleneck. Expert system technology is used for many different aspects of the data management system, including the direct user interface, the interface to the data analysis routines, and the analysis of instrument status.
2015-01-01
Background Good outcomes during pregnancy and childbirth are related to availability, utilisation and effective implementation of essential interventions for labour and childbirth. The majority of the estimated 289,000 maternal deaths, 2.8 million neonatal deaths and 2.6 million stillbirths every year could be prevented by improving access to and scaling up quality care during labour and birth. Methods The bottleneck analysis tool was applied in 12 countries in Africa and Asia as part of the Every Newborn Action Plan process. Country workshops engaged technical experts to complete the survey tool, which is designed to synthesise and grade health system "bottlenecks", factors that hinder the scale up, of maternal-newborn intervention packages. We used quantitative and qualitative methods to analyse the bottleneck data, combined with literature review, to present priority bottlenecks and actions relevant to different health system building blocks for skilled birth attendance and basic and comprehensive emergency obstetric care. Results Across 12 countries the most critical bottlenecks identified by workshop participants for skilled birth attendance were health financing (10 out of 12 countries) and health workforce (9 out of 12 countries). Health service delivery bottlenecks were found to be the most critical for both basic and comprehensive emergency obstetric care (9 out of 12 countries); health financing was identified as having critical bottlenecks for comprehensive emergency obstetric care (9 out of 12 countries). Solutions to address health financing bottlenecks included strengthening national financing mechanisms and removing financial barriers to care seeking. For addressing health workforce bottlenecks, improved human resource planning is needed, including task shifting and improving training quality. For health service delivery, proposed solutions included improving quality of care and establishing public private partnerships. Conclusions Progress towards the 2030 targets for ending preventable maternal and newborn deaths is dependent on improving quality of care during birth and the immediate postnatal period. Strengthening national health systems to improve maternal and newborn health, as a cornerstone of universal health coverage, will only be possible by addressing specific health system bottlenecks during labour and birth, including those within health workforce, health financing and health service delivery. PMID:26390886
Computer-assisted knowledge acquisition for hypermedia systems
NASA Technical Reports Server (NTRS)
Steuck, Kurt
1990-01-01
The usage of procedural and declarative knowledge to set up the structure or 'web' of a hypermedia environment is described. An automated knowledge acquisition tool was developed that helps a knowledge engineer elicit and represent an expert's knowledge involved in performing procedural tasks. The tool represents both procedural and prerequisite, declarative knowledge that supports each activity performed by the expert. This knowledge is output and subsequently read by a hypertext scripting language to generate the link between blank, but labeled cards. Each step of the expert's activity and each piece of supporting declarative knowledge is set up as an empty node. An instructional developer can then enter detailed instructional material concerning each step and declarative knowledge into these empty nodes. Other research is also described that facilitates the translation of knowledge from one form into a form more readily useable by computerized systems.
Kurashige, Hiroki; Yamashita, Yuichi; Hanakawa, Takashi; Honda, Manabu
2018-01-01
Knowledge acquisition is a process in which one actively selects a piece of information from the environment and assimilates it with prior knowledge. However, little is known about the neural mechanism underlying selectivity in knowledge acquisition. Here we executed a 2-day human experiment to investigate the involvement of characteristic spontaneous activity resembling a so-called "preplay" in selectivity in sentence comprehension, an instance of knowledge acquisition. On day 1, we presented 10 sentences (prior sentences) that were difficult to understand on their own. On the following day, we first measured the resting-state functional magnetic resonance imaging (fMRI). Then, we administered a sentence comprehension task using 20 new sentences (posterior sentences). The posterior sentences were also difficult to understand on their own, but some could be associated with prior sentences to facilitate their understanding. Next, we measured the posterior sentence-induced fMRI to identify the neural representation. From the resting-state fMRI, we extracted the appearances of activity patterns similar to the neural representations for posterior sentences. Importantly, the resting-state fMRI was measured before giving the posterior sentences, and thus such appearances could be considered as preplay-like or prototypical neural representations. We compared the intensities of such appearances with the understanding of posterior sentences. This gave a positive correlation between these two variables, but only if posterior sentences were associated with prior sentences. Additional analysis showed the contribution of the entorhinal cortex, rather than the hippocampus, to the correlation. The present study suggests that prior knowledge-based arrangement of neural activity before an experience contributes to the active selection of information to be learned. Such arrangement prior to an experience resembles preplay activity observed in the rodent brain. In terms of knowledge acquisition, the present study leads to a new view of the brain (or more precisely of the brain's knowledge) as an autopoietic system in which the brain (or knowledge) selects what it should learn by itself, arranges preplay-like activity as a position for the new information in advance, and actively reorganizes itself.
Kurashige, Hiroki; Yamashita, Yuichi; Hanakawa, Takashi; Honda, Manabu
2018-01-01
Knowledge acquisition is a process in which one actively selects a piece of information from the environment and assimilates it with prior knowledge. However, little is known about the neural mechanism underlying selectivity in knowledge acquisition. Here we executed a 2-day human experiment to investigate the involvement of characteristic spontaneous activity resembling a so-called “preplay” in selectivity in sentence comprehension, an instance of knowledge acquisition. On day 1, we presented 10 sentences (prior sentences) that were difficult to understand on their own. On the following day, we first measured the resting-state functional magnetic resonance imaging (fMRI). Then, we administered a sentence comprehension task using 20 new sentences (posterior sentences). The posterior sentences were also difficult to understand on their own, but some could be associated with prior sentences to facilitate their understanding. Next, we measured the posterior sentence-induced fMRI to identify the neural representation. From the resting-state fMRI, we extracted the appearances of activity patterns similar to the neural representations for posterior sentences. Importantly, the resting-state fMRI was measured before giving the posterior sentences, and thus such appearances could be considered as preplay-like or prototypical neural representations. We compared the intensities of such appearances with the understanding of posterior sentences. This gave a positive correlation between these two variables, but only if posterior sentences were associated with prior sentences. Additional analysis showed the contribution of the entorhinal cortex, rather than the hippocampus, to the correlation. The present study suggests that prior knowledge-based arrangement of neural activity before an experience contributes to the active selection of information to be learned. Such arrangement prior to an experience resembles preplay activity observed in the rodent brain. In terms of knowledge acquisition, the present study leads to a new view of the brain (or more precisely of the brain’s knowledge) as an autopoietic system in which the brain (or knowledge) selects what it should learn by itself, arranges preplay-like activity as a position for the new information in advance, and actively reorganizes itself. PMID:29662446
NASA Technical Reports Server (NTRS)
Chien, Steve A.
1996-01-01
A key obstacle hampering fielding of AI planning applications is the considerable expense of developing, verifying, updating, and maintainting the planning knowledge base (KB). Planning systems must be able to compare favorably in terms of software lifecycle costs to other means of automation such as scripts or rule-based expert systems. This paper describes a planning application of automated imaging processing and our overall approach to knowledge acquisition for this application.
Challenges and promises of integrating knowledge engineering and qualitative methods
NASA Astrophysics Data System (ADS)
Lundberg, C. Gustav; Holm, Gunilla
Our goal is to expose some of the close ties that exist between knowledge engineering (KE) and qualitative methodology (QM). Many key concepts of qualitative research, for example meaning, commonsense, understanding, and everyday life, overlap with central research concerns in artificial intelligence. These shared interests constitute a largely unexplored avenue for interdisciplinary cooperation. We compare and take some steps toward integrating two historically diverse methodologies by exploring the commonalities of KE and QM both from a substantive and a methodological/technical perspective. In the second part of this essay, we address knowledge acquisition problems and procedures. Knowledge acquisition within KE has been based primarily on cognitive psychology/science foundations, whereas knowledge acquisition within QM has a broader foundation in phenomenology, symbolic interactionism, and ethnomethodology. Our discussion and examples are interdisciplinary in nature. We do not suggest that there is a clash between the KE and QM frameworks, but rather that the lack of communication potentially may limit each framework's future development.
The acquisition of biological knowledge during childhood: Cognitive conflict or tabula rasa?
NASA Astrophysics Data System (ADS)
Lawson, Anton E.
Clinical interviews were conducted with three elementary school children, who varied in age but not in family or school environment, to determine the extent to which they held naive misconceptions about important biological topics and to determine agewise trends in the development of biological knowledge. Does early biological knowledge acquisition follow a pattern of spontaneous naive theory construction and cognitive conflict or does it follow a pattern of gradual accretion to an initially blank slate? Contrary to findings in the physical sciences, little evidence was found for biological misconceptions as knowledge acquisition appeared to more directly follow the gradual accretion hypothesis with the primary source of that knowledge adult authority rather than personal experience. However, conceptual change teaching is still advocated due to its ability to provoke students to consider and test alternative conceptions (even if they are not their own) as a means of encouraging the development of important general reasoning patterns utilized in the testing of causal hypotheses.
DOT National Transportation Integrated Search
2004-11-01
The motivation behind the Transportation Infrastructure and Traffic Management Analysis of : Cross Border Bottlenecks study was generated by the U.S.-Mexico Border Partnership Action : Plan (Action item #2 of the 22-Point Smart Border Action Plan: De...
The Role of Knowledge Base and Declarative Metamemory in the Acquisition of a Reading Strategy.
ERIC Educational Resources Information Center
Gaultney, Jane F.; Hack-Weiner, Nancy
A study examined whether previous knowledge facilitates the acquisition of a reading comprehension strategy by children who are poor readers. Subjects, 54 fourth- and fifth-grade boys in Palm Beach County, Florida, who were poor readers and baseball experts, were trained in the use of a reading strategy (asking "why" questions), with…
ERIC Educational Resources Information Center
Schoor, Cornelia; Bannert, Maria
2011-01-01
Addressing a drawback in current research on computer-supported collaborative learning (CSCL), this study investigated the influence of motivation on learning activities and knowledge acquisition during CSCL. Participants' (N = 200 university students) task was to develop a handout for which they had first an individual preparing phase followed by…
Interactions among Children in Scholastic Contexts and Knowledge Acquisition in Biology
ERIC Educational Resources Information Center
Ponce, Corinne; Schneeberger, Patricia
2002-01-01
This article presents the first results of an investigation in a scholastic context aimed a determining the conditions that favour the acquisition of knowledge in biology within interactions in groups of 4 pupils. There were three work sessions in small groups, and some sessions in class groups. The pupils' conceptions were assessed at the…
ERIC Educational Resources Information Center
Huang, Kun; Chen, Ching-Huei; Wu, Wen-Shiuan; Chen, Wei-Yu
2015-01-01
This study investigated how question prompts and feedback influenced knowledge acquisition and cognitive load when learning Newtonian mechanics within a web-based multimedia module. Participants were one hundred eighteen 9th grade students who were randomly assigned to one of four experimental conditions, forming a 2 x 2 factorial design with the…
ERIC Educational Resources Information Center
Dabrowska, Ewa; Tomasello, Michael
2008-01-01
Rapid acquisition of linguistic categories or constructions is sometimes regarded as evidence of innate knowledge. In this paper, we examine Polish children's early understanding of an idiosyncratic, language-specific construction involving the instrumental case--which could not be due to innate knowledge. Thirty Polish-speaking children aged 2; 6…
Curriculum Sequencing and the Acquisition of Clock-Reading Skills among Chinese and Flemish Children
ERIC Educational Resources Information Center
Burny, Elise; Valcke, Martin; Desoete, Annemie; Van Luit, Johannes E. Hans
2013-01-01
The present study addresses the impact of the curriculum on primary school children's acquisition of clock-reading knowledge from analog and digital clocks. Focusing on Chinese and Flemish children's clock-reading knowledge, the study is about whether the differences in sequencing of learning and instruction opportunities--as defined by the…
The Relation between Individual Interest and Knowledge Acquisition
ERIC Educational Resources Information Center
Rotgans, Jerome I.; Schmidt, Henk G.
2017-01-01
The objective of this study was to examine how individual interest and knowledge acquisition are causally related. Three hypotheses were tested using a cross-lagged panel analysis (N = 186) and two quasi-experimental studies (N = 68 and N = 108) involving students from schools in Singapore. The first hypothesis is the broadly shared standard…
Fonseca, Luciana Mara Monti; Scochi, Carmen Gracinda Silvan; de Mello, Débora Falleiros
2002-01-01
The study aims at verifying knowledge acquisition through health education activities mediated by the use of an educational game on breast-feeding and basic care provided to the newborn, in rooming-in. Study accomplished at a philanthropic maternity of Ribeirão Preto-SP. Educational activities were accomplished in group, coordinated by the nurse, using board game. Through structured interview guided by a route before and after-game, the authors verified the knowledge acquisition, classifying the answers in insufficient (0-4), regular (5-9), good (10-14) and excellent (15-20). Of the mothers' previous knowledge, 16.7% of answers were excellent increasing for 77.8% after participation in the educational activity. They concluded that the game constituted in appropriate strategy to facilitate change of experiences between puerperas and the development of the health education through ludic-pedagogical activities.
Meta-tools for software development and knowledge acquisition
NASA Technical Reports Server (NTRS)
Eriksson, Henrik; Musen, Mark A.
1992-01-01
The effectiveness of tools that provide support for software development is highly dependent on the match between the tools and their task. Knowledge-acquisition (KA) tools constitute a class of development tools targeted at knowledge-based systems. Generally, KA tools that are custom-tailored for particular application domains are more effective than are general KA tools that cover a large class of domains. The high cost of custom-tailoring KA tools manually has encouraged researchers to develop meta-tools for KA tools. Current research issues in meta-tools for knowledge acquisition are the specification styles, or meta-views, for target KA tools used, and the relationships between the specification entered in the meta-tool and other specifications for the target program under development. We examine different types of meta-views and meta-tools. Our current project is to provide meta-tools that produce KA tools from multiple specification sources--for instance, from a task analysis of the target application.
DOT National Transportation Integrated Search
2004-11-01
The motivation behind the Transportation Infrastructure and Traffic Management Analysis of : Cross Border Bottlenecks study was generated by the U.S.-Mexico Border Partnership Action : Plan (Action item #2 of the 22-Point Smart Border Action Plan: De...
On acquisition of programming knowledge
NASA Technical Reports Server (NTRS)
Amin, Ashok T.
1987-01-01
For the evolving discipline of programming, acquisition of programming knowledge is a difficult issue. Common knowledge results from the acceptance of proven techniques based on results of formal inquiries into the nature of the programming process. This is a rather slow process. In addition, the vast body of common knowledge needs to be explicated to a low enough level of details for it to be represented in the machine processable form. It is felt that this is an impediment to the progress of automatic programming. The importance of formal approaches cannot be overstated since their contributions lead to quantum leaps in the state of the art.
Knowledge acquisition for medical diagnosis using collective intelligence.
Hernández-Chan, G; Rodríguez-González, A; Alor-Hernández, G; Gómez-Berbís, J M; Mayer-Pujadas, M A; Posada-Gómez, R
2012-11-01
The wisdom of the crowds (WOC) is the process of taking into account the collective opinion of a group of individuals rather than a single expert to answer a question. Based on this assumption, the use of processes based on WOC techniques to collect new biomedical knowledge represents a challenging and cutting-edge trend on biomedical knowledge acquisition. The work presented in this paper shows a new schema to collect diagnosis information in Diagnosis Decision Support Systems (DDSS) based on collective intelligence and consensus methods.
Estimating Bottleneck Bandwidth using TCP
NASA Technical Reports Server (NTRS)
Allman, Mark
1998-01-01
Various issues associated with estimating bottleneck bandwidth using TCP are presented in viewgraph form. Specific topics include: 1) Why TCP is wanted to estimate the bottleneck bandwidth; 2) Setting ssthresh to an appropriate value to reduce loss; 3) Possible packet-pair solutions; and 4) Preliminary results: ACTS and the Internet.
ERIC Educational Resources Information Center
Luo, Yanyan
2009-01-01
In the article, the author tries to find out the main factors that affect the subject's vocabulary acquisition by an investigation. It is concluded that vocabulary acquisition models and strategies are something external, what really works upon vocabulary acquisition is the intermediary system of cognition including the knowledge structure and…
Research on knowledge representation, machine learning, and knowledge acquisition
NASA Technical Reports Server (NTRS)
Buchanan, Bruce G.
1987-01-01
Research in knowledge representation, machine learning, and knowledge acquisition performed at Knowledge Systems Lab. is summarized. The major goal of the research was to develop flexible, effective methods for representing the qualitative knowledge necessary for solving large problems that require symbolic reasoning as well as numerical computation. The research focused on integrating different representation methods to describe different kinds of knowledge more effectively than any one method can alone. In particular, emphasis was placed on representing and using spatial information about three dimensional objects and constraints on the arrangement of these objects in space. Another major theme is the development of robust machine learning programs that can be integrated with a variety of intelligent systems. To achieve this goal, learning methods were designed, implemented and experimented within several different problem solving environments.
Semantics driven approach for knowledge acquisition from EMRs.
Perera, Sujan; Henson, Cory; Thirunarayan, Krishnaprasad; Sheth, Amit; Nair, Suhas
2014-03-01
Semantic computing technologies have matured to be applicable to many critical domains such as national security, life sciences, and health care. However, the key to their success is the availability of a rich domain knowledge base. The creation and refinement of domain knowledge bases pose difficult challenges. The existing knowledge bases in the health care domain are rich in taxonomic relationships, but they lack nontaxonomic (domain) relationships. In this paper, we describe a semiautomatic technique for enriching existing domain knowledge bases with causal relationships gleaned from Electronic Medical Records (EMR) data. We determine missing causal relationships between domain concepts by validating domain knowledge against EMR data sources and leveraging semantic-based techniques to derive plausible relationships that can rectify knowledge gaps. Our evaluation demonstrates that semantic techniques can be employed to improve the efficiency of knowledge acquisition.
Bottleneck Concepts in Psychology: Exploratory First Steps
ERIC Educational Resources Information Center
Gurung, Regan A. R.; Landrum, R. Eric
2013-01-01
The authors take an initial step in identifying potential bottleneck concepts in psychology, that is, concepts that are deceptively difficult, perhaps due to student overconfidence. In order to first identify bottleneck concepts, faculty (n = 65) rated the difficulty of 91 psychological concepts from across the discipline. Students (n = 35) rated…
The Impact of Population Bottlenecks on Microbial Adaptation
NASA Astrophysics Data System (ADS)
LeClair, Joshua S.; Wahl, Lindi M.
2018-07-01
Population bottlenecks—sudden, severe reductions in population size—are ubiquitous in nature. Because of their critical implications for conservation genetics, the effects of population bottlenecks on the loss of genetic diversity have been well studied. Bottlenecks also have important implications for adaptation, however, and these effects have been addressed more recently, typically in microbial populations. In this short review, we survey both experimental and theoretical work describing the impact of population bottlenecks on microbial adaptation. Focusing on theoretical contributions, we highlight emerging insights and conclude with several open questions of interest in the field.
Bottlenecks and Waiting Points in Nucleosynthesis in X-ray bursts and Novae
NASA Astrophysics Data System (ADS)
Smith, Michael S.; Sunayama, Tomomi; Hix, W. Raphael; Lingerfelt, Eric J.; Nesaraja, Caroline D.
2010-08-01
To better understand the energy generation and element synthesis occurring in novae and X-ray bursts, we give quantitative definitions to the concepts of ``bottlenecks'' and ``waiting points'' in the thermonuclear reaction flow. We use these criteria to search for bottlenecks and waiting points in post-processing element synthesis explosion simulations. We have incorporated these into the Computational Infrastructure for Nuclear Astrophysics, a suite of nuclear astrophysics codes available online at nucastrodata.org, so that anyone may perform custom searches for bottlenecks and waiting points.
Bottlenecks and Waiting Points in Nucleosynthesis in X-ray bursts and Novae
DOE Office of Scientific and Technical Information (OSTI.GOV)
Smith, Michael S.; Hix, W. Raphael; Nesaraja, Caroline D.
2010-08-12
To better understand the energy generation and element synthesis occurring in novae and X-ray bursts, we give quantitative definitions to the concepts of ''bottlenecks'' and ''waiting points'' in the thermonuclear reaction flow. We use these criteria to search for bottlenecks and waiting points in post-processing element synthesis explosion simulations. We have incorporated these into the Computational Infrastructure for Nuclear Astrophysics, a suite of nuclear astrophysics codes available online at nucastrodata.org, so that anyone may perform custom searches for bottlenecks and waiting points.
Bascandziev, Igor; Tardiff, Nathan; Zaitchik, Deborah; Carey, Susan
2018-08-01
Some episodes of learning are easier than others. Preschoolers can learn certain facts, such as "my grandmother gave me this purse," only after one or two exposures (easy to learn; fast mapping), but they require several years to learn that plants are alive or that the sun is not alive (hard to learn). One difference between the two kinds of knowledge acquisition is that hard cases often require conceptual construction, such as the construction of the biological concept alive, whereas easy cases merely involve forming new beliefs formulated over concepts the child already has (belief revision, a form of knowledge enrichment). We asked whether different domain-general cognitive resources support these two types of knowledge acquisition (conceptual construction and knowledge enrichment that supports fast mapping) by testing 82 6-year-olds in a pre-training/training/post-training study. We measured children's improvement in an episode involving theory construction (the beginning steps of acquisition of the framework theory of vitalist biology, which requires conceptual change) and in an episode involving knowledge enrichment alone (acquisition of little known facts about animals, such as the location of crickets' ears and the color of octopus blood). In addition, we measured children's executive functions and receptive vocabulary to directly compare the resources drawn upon in the two episodes of learning. We replicated and extended previous findings highlighting the differences between conceptual construction and knowledge enrichment, and we found that Executive Functions predict improvement on the Vitalism battery but not on the Fun Facts battery and that Receptive Vocabulary predicts improvement the Fun Facts battery but not on the Vitalism battery. This double dissociation provides new evidence for the distinction between the two types of knowledge acquisition, and bears on the nature of the learning mechanisms involved in each. Copyright © 2018 Elsevier Inc. All rights reserved.
Processing bottlenecks in dual-task performance: structural limitation or strategic postponement?
NASA Technical Reports Server (NTRS)
Ruthruff, E.; Pashler, H. E.; Klaassen, A.
2001-01-01
Recent evidence indicates that a central bottleneck causes much of the slowing that occurs when two tasks are performed at the same time. This bottleneck might reflect a structural limitation inherent in the cognitive architecture. Alternatively, the bottleneck might reflect strategic (i.e., voluntary) postponement, induced by instructions to emphasize one task over the other. To distinguish structural limitations from strategic postponement, we examine a new paradigm in which subjects are told to place equal emphasis on both tasks and to emit both responses at about the same time. An experiment using this paradigm demonstrated patterns of interference that cannot easily be attributed to strategic postponement, preparation effects, or conflicts in response production. The data conform closely to the predictions of structural central bottleneck models.
Knowledge Engineering and Education.
ERIC Educational Resources Information Center
Lopez, Antonio M., Jr.; Donlon, James
2001-01-01
Discusses knowledge engineering, computer software, and possible applications in the field of education. Highlights include the distinctions between data, information, and knowledge; knowledge engineering as a subfield of artificial intelligence; knowledge acquisition; data mining; ontology development for subject terms; cognitive apprentices; and…
ERIC Educational Resources Information Center
Yoder, Paul J.; Woynaroski, Tiffany
2015-01-01
Seven empirical studies from this special issue and an overview chapter are reviewed to illustrate several points about studying the possible effects of treatment intensity manipulations on generalized skill or knowledge acquisition in students with disabilities. First, we make a case in favor of studying intensity as separate from complexity and…
ERIC Educational Resources Information Center
Demetriadis, Stavros; Egerter, Tina; Hanisch, Frank; Fischer, Frank
2011-01-01
This study investigates the effectiveness of using peer review in the context of scripted collaboration to foster both domain-specific and domain-general knowledge acquisition in the computer science domain. Using a one-factor design with a script and a control condition, students worked in small groups on a series of computer science problems…
ERIC Educational Resources Information Center
Tekinarslan, Erkan
2013-01-01
The purpose of this study is to investigate the effects of screencasts on the Turkish undergraduate students' achievement and knowledge acquisitions in spreadsheet applications. The methodology of the study is based on a pretest-posttest experimental design with a control group. A total of 66 undergraduate students in two groups (n = 33 in…
ERIC Educational Resources Information Center
Vosniadou, Stella
Analogical reasoning is one mechanism that has been recognized as having the potential of bringing prior knowledge to bear on the acquisition of new information. Analogical reasoning involves the identification and transfer of structural information from a known system to a new and relatively unknown system. The productive use of analogy is often…
Demographic attributes and knowledge acquisition among graduate-entry medical students.
Finucane, Paul; Flannery, Denise; McGrath, Deirdre; Saunders, Jean
2013-01-01
Recent changes to undergraduate (basic) medical education in Ireland have linked an expansion of student numbers with wide-ranging reforms. Medical schools have broadened access by admitting more mature students from diverse backgrounds and have increased their international student numbers. This has resulted in major changes to the demographic profile of students at Irish medical schools. To determine whether the demographic characteristics of students impact on their academic performance and specifically on their rate of knowledge acquisition. As a formative assessment exercise, we administered a progress test to all students twice each year during a 4 year graduate-entry medical programme. We compared scores over time between students from different age cohorts, of different gender, of different nationalities and from different academic backgrounds. In the 1143 tests taken by 285 students to date, there were no significant differences in the rate of knowledge acquisition between the various groups. Early in the course, students from a non-biological science background performed less well than others but outperformed their peers by the time of graduation. Neither age, gender, nationality nor academic background impacts on the rate of knowledge acquisition among graduate-entry medical students.
Dokas, Ioannis M; Panagiotakopoulos, Demetrios C
2006-08-01
The available expertise on managing and operating solid waste management (SWM) facilities varies among countries and among types of facilities. Few experts are willing to record their experience, while few researchers systematically investigate the chains of events that could trigger operational failures in a facility; expertise acquisition and dissemination, in SWM, is neither popular nor easy, despite the great need for it. This paper presents a knowledge acquisition process aimed at capturing, codifying and expanding reliable expertise and propagating it to non-experts. The knowledge engineer (KE), the person performing the acquisition, must identify the events (or causes) that could trigger a failure, determine whether a specific event could trigger more than one failure, and establish how various events are related among themselves and how they are linked to specific operational problems. The proposed process, which utilizes logic diagrams (fault trees) widely used in system safety and reliability analyses, was used for the analysis of 24 common landfill operational problems. The acquired knowledge led to the development of a web-based expert system (Landfill Operation Management Advisor, http://loma.civil.duth.gr), which estimates the occurrence possibility of operational problems, provides advice and suggests solutions.
The Roles of Knowledge Professionals for Knowledge Management.
ERIC Educational Resources Information Center
Kim, Seonghee
This paper starts by exploring the definition of knowledge and knowledge management; examples of acquisition, creation, packaging, application, and reuse of knowledge are provided. It then considers the partnership for knowledge management and especially how librarians as knowledge professionals, users, and technology experts can contribute to…
48 CFR 801.690-1 - Definitions.
Code of Federal Regulations, 2011 CFR
2011-10-01
... Acquisition Continuing Education Program, a program to provide VA's acquisition workforce with classroom knowledge to further develop their acquisition skills. The program supports VA personnel in the GS 1102... Certification (see OFPP Policy Letter 05-01, paragraph 8) means a certification program developed by the Federal...
48 CFR 50.103-5 - Processing cases.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Processing cases. 50.103-5 Section 50.103-5 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT... knowledge of individuals when documentary evidence is lacking, and audits if considered necessary to...
Relative frequency of knowledge of performance and motor skill learning.
Weeks, D L; Kordus, R N
1998-09-01
This study examined the effects of variations in relative frequency of knowledge of performance (KP) on acquisition, retention, and transfer of form for a multilimb closed sport skill. Two groups received either 100% relative frequency of KP or 33% relative frequency of KP while learning the soccer throw-in skill. Participants were boys between the ages of 11 and 14 years who were unfamiliar with the skill. Participants performed a 30-trial acquisition phase in which KP was provided about one of eight aspects of form. Following acquisition, five trial retention and transfer (to a target at a different distance than experienced in acquisition) tests were administered at 5 min, 24 hr, and 72 hr. Although no group differences were found for accuracy scores, the 33% group had higher form scores in acquisition and all retention and transfer tests. It was concluded that reducing the relative frequency of KP eliminated a dependency on KP to guide performance in acquisition, which was beneficial for maintaining form in conditions in which KP was absent.
Wang, Lin; Liu, Simin; Niu, Tianhua; Xu, Xin
2005-03-18
Single nucleotide polymorphisms (SNPs) provide an important tool in pinpointing susceptibility genes for complex diseases and in unveiling human molecular evolution. Selection and retrieval of an optimal SNP set from publicly available databases have emerged as the foremost bottlenecks in designing large-scale linkage disequilibrium studies, particularly in case-control settings. We describe the architectural structure and implementations of a novel software program, SNPHunter, which allows for both ad hoc-mode and batch-mode SNP search, automatic SNP filtering, and retrieval of SNP data, including physical position, function class, flanking sequences at user-defined lengths, and heterozygosity from NCBI dbSNP. The SNP data extracted from dbSNP via SNPHunter can be exported and saved in plain text format for further down-stream analyses. As an illustration, we applied SNPHunter for selecting SNPs for 10 major candidate genes for type 2 diabetes, including CAPN10, FABP4, IL6, NOS3, PPARG, TNF, UCP2, CRP, ESR1, and AR. SNPHunter constitutes an efficient and user-friendly tool for SNP screening, selection, and acquisition. The executable and user's manual are available at http://www.hsph.harvard.edu/ppg/software.htm
Shapiro, Lori R.; Scully, Erin D.; Straub, Timothy J.; Park, Jihye; Stephenson, Andrew G.; Beattie, Gwyn A.; Gleason, Mark L.; Kolter, Roberto; Coelho, Miguel C.; De Moraes, Consuelo M.; Mescher, Mark C.; Zhaxybayeva, Olga
2016-01-01
Modern industrial agriculture depends on high-density cultivation of genetically similar crop plants, creating favorable conditions for the emergence of novel pathogens with increased fitness in managed compared with ecologically intact settings. Here, we present the genome sequence of six strains of the cucurbit bacterial wilt pathogen Erwinia tracheiphila (Enterobacteriaceae) isolated from infected squash plants in New York, Pennsylvania, Kentucky, and Michigan. These genomes exhibit a high proportion of recent horizontal gene acquisitions, invasion and remarkable amplification of mobile genetic elements, and pseudogenization of approximately 20% of the coding sequences. These genome attributes indicate that E. tracheiphila recently emerged as a host-restricted pathogen. Furthermore, chromosomal rearrangements associated with phage and transposable element proliferation contribute to substantial differences in gene content and genetic architecture between the six E. tracheiphila strains and other Erwinia species. Together, these data lead us to hypothesize that E. tracheiphila has undergone recent evolution through both genome decay (pseudogenization) and genome expansion (horizontal gene transfer and mobile element amplification). Despite evidence of dramatic genomic changes, the six strains are genetically monomorphic, suggesting a recent population bottleneck and emergence into E. tracheiphila’s current ecological niche. PMID:26992913
NASA Technical Reports Server (NTRS)
Modesitt, Kenneth L.
1990-01-01
A prediction was made that the terms expert systems and knowledge acquisition would begin to disappear over the next several years. This is not because they are falling into disuse; it is rather that practitioners are realizing that they are valuable adjuncts to software engineering, in terms of problem domains addressed, user acceptance, and in development methodologies. A specific problem was discussed, that of constructing an automated test analysis system for the Space Shuttle Main Engine. In this domain, knowledge acquisition was part of requirements systems analysis, and was performed with the aid of a powerful inductive ESBT in conjunction with a computer aided software engineering (CASE) tool. The original prediction is not a very risky one -- it has already been accomplished.
Adaptive Knowledge Management of Project-Based Learning
ERIC Educational Resources Information Center
Tilchin, Oleg; Kittany, Mohamed
2016-01-01
The goal of an approach to Adaptive Knowledge Management (AKM) of project-based learning (PBL) is to intensify subject study through guiding, inducing, and facilitating development knowledge, accountability skills, and collaborative skills of students. Knowledge development is attained by knowledge acquisition, knowledge sharing, and knowledge…
The Source of Execution-Related Dual-Task Interference: Motor Bottleneck or Response Monitoring?
ERIC Educational Resources Information Center
Bratzke, Daniel; Rolke, Bettina; Ulrich, Rolf
2009-01-01
The present study assessed the underlying mechanism of execution-related dual-task interference in the psychological refractory period (PRP) paradigm. The motor bottleneck hypothesis attributes this interference to a processing limitation at the motor level. By contrast, the response monitoring hypothesis attributes it to a bottleneck process that…
NASA Astrophysics Data System (ADS)
Zahari, R.; Ariffin, M. H.; Othman, N.
2018-02-01
Free Trade Agreements as implemented by Malaysian government calls out local businesses such as landscape architecture consultant firm to explore internationally and strengthen their performance to compete locally. Performance of landscape architecture firm as a design firm depends entirely on creativity of the subordinates in the firm. Past research has neglected studying the influence of a leader’s capitals on subordinates’ creativity, especially in Malaysian landscape architecture firms. The aim of this research is to investigate the influence of subordinates’ perceptions of the leader’s Bourdieu capitals towards promoting subordinate’s creative behaviours in Malaysian Landscape Architecture firms. The sample chosen for this research are subordinates in registered landscape architecture firm. Data was collected using qualitative semi-structured interviews with 13 respondents and analysed using Qualitative Category Coding. Aspects of the leader’s social capital (i.e. knowledge acquisition, problem solving, motivation boosting), human capital (guidance, demotivating leadership, experiential knowledge, knowledge acquisition), and emotional capital (chemistry with leader, respect, knowledge acquisition, trust, understanding, self-inflicted demotivation) that influence subordinates’ creativity were uncovered from the data. The main finding is that the leader’s capitals promote the subordinate landscape architects or assistant landscape architect to be more creative based on three main things, first is knowledge acquisition, motivation, and ability for the leader to influence through positive relationship. The finding contributes to a new way of understanding the leader’s characteristics that influence subordinates’ creativity.
Language acquisition and use: learning and applying probabilistic constraints.
Seidenberg, M S
1997-03-14
What kinds of knowledge underlie the use of language and how is this knowledge acquired? Linguists equate knowing a language with knowing a grammar. Classic "poverty of the stimulus" arguments suggest that grammar identification is an intractable inductive problem and that acquisition is possible only because children possess innate knowledge of grammatical structure. An alternative view is emerging from studies of statistical and probabilistic aspects of language, connectionist models, and the learning capacities of infants. This approach emphasizes continuity between how language is acquired and how it is used. It retains the idea that innate capacities constrain language learning, but calls into question whether they include knowledge of grammatical structure.
Diagnosis: Reasoning from first principles and experiential knowledge
NASA Technical Reports Server (NTRS)
Williams, Linda J. F.; Lawler, Dennis G.
1987-01-01
Completeness, efficiency and autonomy are requirements for suture diagnostic reasoning systems. Methods for automating diagnostic reasoning systems include diagnosis from first principles (i.e., reasoning from a thorough description of structure and behavior) and diagnosis from experiential knowledge (i.e., reasoning from a set of examples obtained from experts). However, implementation of either as a single reasoning method fails to meet these requirements. The approach of combining reasoning from first principles and reasoning from experiential knowledge does address the requirements discussed above and can possibly ease some of the difficulties associated with knowledge acquisition by allowing developers to systematically enumerate a portion of the knowledge necessary to build the diagnosis program. The ability to enumerate knowledge systematically facilitates defining the program's scope, completeness, and competence and assists in bounding, controlling, and guiding the knowledge acquisition process.
Markert, Ronald J; O'Neill, Sally C; Bhatia, Subhash C
2003-01-01
The objectives of continuing medical education (CME) programs include knowledge acquisition, skill development, clinical reasoning and decision making, and health care outcomes. We conducted a year-long medical education research study in which knowledge acquisition in our CME programs was assessed. A randomized separate-sample pretest/past-test design, a quasi-experimental technique, was used. Nine CME programs with a sufficient number of participants were identified a priori. Knowledge acquisition was compared between the control group and the intervention group for the nine individual programs and for the combined programs. A total of 667 physicians, nurses, and other health professionals participated. Significant gain in knowledge was found for six programs: Perinatology, Pain Management, Fertility Care 2, Pediatrics, Colorectal Diseases, and Alzheimer's Disease (each p < .001). Also, the intervention group differed from the control group when the nine programs were combined (p < .001), with an effect size of .84. The use of sound quasi-experimental research methodology (separate-sample pretest/post-test design), the inclusion of a representative sample of CME programs, and the analysis of nearly 700 subjects led us to have confidence in concluding that our CME participants acquired a meaningful amount of new knowledge.
LIS Professionals as Knowledge Engineers.
ERIC Educational Resources Information Center
Poulter, Alan; And Others
1994-01-01
Considers the role of library and information science professionals as knowledge engineers. Highlights include knowledge acquisition, including personal experience, interviews, protocol analysis, observation, multidimensional sorting, printed sources, and machine learning; knowledge representation, including production rules and semantic nets;…
ERIC Educational Resources Information Center
Hannon, Kevin
2017-01-01
Contact time with students is becoming more valuable and must be utilized efficiently. Unfortunately, many students attend anatomy lectures and labs ill-prepared, and this limits efficiency. To address this issue we have created an interactive mobile app designed to facilitate the acquisition and transfer of critical anatomical knowledge in…
ERIC Educational Resources Information Center
D'Alba, Adriana
2012-01-01
The main purpose of this mixed methods research was to explore and analyze visitors' overall experience while they attended a museum exhibition, and examine how this experience was affected by previously using a virtual 3dimensional representation of the museum itself. The research measured knowledge acquisition in a virtual museum, and compared…
ERIC Educational Resources Information Center
Melo, Mário; Miranda, Guilhermina Lobato
2015-01-01
This study was designed to investigate the effects of two instructional approaches (4C-ID versus conventional) on learners' knowledge-acquisition and learning transfer of the electrical circuits content in Physics. Participants were 129 9th graders from a secondary school in Lisbon, M = 14.3 years, SD = 0.54. The participants were divided in two…
Aptitude Level and the Acquisition of Skills and Knowledges in a Variety of Military Training Tasks.
ERIC Educational Resources Information Center
Fox, Wayne L.; And Others
To assess the effects of wide aptitude differences on the acquisition of military knowledges and skills, a sample of 183 Army recruits was divided into three maximally distant aptitude groups on the basis of Armed Forces Qualifying Test (AFQT) scores: high aptitude (AFQT 90-99); middle aptitude (AFQT 45-55); low aptitude (AFQT 10-21). Recruits…
ERIC Educational Resources Information Center
Kapli, Natalia V.
2010-01-01
The study investigated the effects of non-segmented multimedia worked examples (NS-MWE), segmented multimedia worked examples (S-MWE), and segmented multimedia worked examples enhanced with self-explanation prompts (S-MWE-SE) on acquisition of conceptual knowledge and problem solving performance in an undergraduate engineering course. In addition,…
ERIC Educational Resources Information Center
Kaheru, Sam J.; Kriek, Jeanne
2016-01-01
A study on the effect of the use of computer simulations (CS) on the acquisition of knowledge and cognitive load was undertaken with 104 Grade 11 learners in four schools in rural South Africa on the physics topic geometrical optics. Owing to the lack of resources a teacher-centred approach was followed in the use of computer simulations. The…
ERIC Educational Resources Information Center
McLean, Monica; Abbas, Andrea; Ashwin, Paul
2015-01-01
This article places itself in conversation with literature about how the experience and outcomes of university education are structured by intersections between social class, ethnicity, gender, age and type of university attended. It addresses undergraduate students' acquisition of sociological knowledge in four diverse university settings. Basil…
Knowledge Creation in Constructivist Learning
ERIC Educational Resources Information Center
Jaleel, Sajna; Verghis, Alie Molly
2015-01-01
In today's competitive global economy characterized by knowledge acquisition, the concept of knowledge management has become increasingly prevalent in academic and business practices. Knowledge creation is an important factor and remains a source of competitive advantage over knowledge management. Constructivism holds that learners learn actively…
Gender and Number Agreement in the Oral Production of Arabic Heritage Speakers
ERIC Educational Resources Information Center
Albirini, Abdulkafi; Benmamoun, Elabbas; Chakrani, Brahim
2013-01-01
Heritage language acquisition has been characterized by various asymmetries, including the differential acquisition rates of various linguistic areas and the unbalanced acquisition of different categories within a single area. This paper examines Arabic heritage speakers' knowledge of subject-verb agreement versus noun-adjective agreement with the…
The Challenge of Acquisitions in the Digital Age
ERIC Educational Resources Information Center
Whittaker, Martha
2008-01-01
People are now beginning to appreciate that acquisitions in the digital world is different. In addition to business acumen and accounting knowledge, a digital-age acquisitions librarian needs to understand scholarly communication and the emerging business models of digital publishing. In this article, the author discusses the challenges and the…
L3 Acquisition of German Adjectival Inflection: A Generative Account
ERIC Educational Resources Information Center
Jaensch, Carol
2011-01-01
Studies testing the knowledge of syntactic properties have resulted in two potentially contrasting proposals in relation to third language acquisition (TLA); the Cumulative Enhancement Model (Flynn et al., 2004), which proposes that previously learned languages will positively affect the acquisition of a third language (L3); and the "second…
Collection Evaluation and Acquisition Budgets: A Kaleidoscope in the Making.
ERIC Educational Resources Information Center
Osburn, Charles B.
1992-01-01
Discusses library collection evaluation and its relationship to the acquisitions budget. Topics addressed include the publishing industry; library services that are more user centered; acquisition of versus access to sources of information and knowledge; the concept of value; library accountability; objectives and setting priorities; and levels of…
How Strategic Is the Central Bottleneck: Can It Be Overcome by Trying Harder?
ERIC Educational Resources Information Center
Ruthruff, Eric; Johnston, James C.; Remington, Roger W.
2009-01-01
Recent dual-task studies suggest that a bottleneck prevents central mental operations from working on more than one task at a time, especially at relatively low practice levels. It remains highly controversial, however, whether this bottleneck is structural (inherent to human cognitive architecture) or merely a strategic choice. If the strategic…
Anatomy of a bottleneck: diagnosing factors limiting population growth in the Puerto Rican Parrot
S.R. Beissinger; Jr Wunderle; J.M. Meyers; B.E. Saether; S. Engen
2008-01-01
The relative importance of genetic, demographic, environmental, and catastrophic processes that maintain population bottlenecks has received little consideration. We evaluate the role of these factors in maintaining the Puerto Rican Parrot (Amazona vittata) in a prolonged bottleneck from 1973 through 2000 despite intensive conservation efforts. We first conduct a risk...
Arias, Ana; Scott, Raymond; Peters, Ove A; McClain, Elizabeth; Gluskin, Alan H
2016-04-01
The aim of this prospective quantitative study was to compare the effect of different instructional formats on dental students' skills and knowledge acquisition for access cavity preparation. All first-year dental students were invited to participate in this study conducted during the four consecutive two-week endodontic rotation courses at the University of the Pacific Arthur A. Dugoni School of Dentistry in spring semester 2015. Four alphabetically distributed intact groups of students were randomly allocated to two groups (n=70 each) that participated in either small-group discussion or a traditional lecture on access preparation. The first outcome measure was skill acquisition, measured by the quality of access cavities prepared in extracted teeth at the conclusion of the session. Two blinded raters scored direct observations on a continuous scale. Knowledge, the second outcome measure, was scored with a multiple-choice and open-ended question test at the end of each two-week session. Data were obtained for 134 of the 140 students, for a 96% response rate. The results showed that students in the small-group discussion groups scored significantly higher than those in the lecture groups when skill performance was tested (p=8.9 × 10(-7)). However, no significant differences were found in the acquisition of knowledge between the two groups on the written test. Active student participation was significantly related to improved manual skill acquisition, but the format of the session does not seem to have had a direct influence on acquired knowledge.
The Meta-Ontology Model of the Fishdisease Diagnostic Knowledge Based on Owl
NASA Astrophysics Data System (ADS)
Shi, Yongchang; Gao, Wen; Hu, Liang; Fu, Zetian
For improving available and reusable of knowledge in fish disease diagnosis (FDD) domain and facilitating knowledge acquisition, an ontology model of FDD knowledge was developed based on owl according to FDD knowledge model. It includes terminology of terms in FDD knowledge and hierarchies of their class.
ERIC Educational Resources Information Center
Scribner, Sylvia
1985-01-01
Activity theory posits that culturally organized actions guide the acquisition and organization of knowledge. This theory was applied to the organization of knowledge within a large milk processing plant. The dairy was found to be organized by social knowledge, yet individuals creatively synthesized several domains of knowledge to organize their…
The Framework of Knowledge Creation for Online Learning Environments
ERIC Educational Resources Information Center
Huang, Hsiu-Mei; Liaw, Shu-Sheng
2004-01-01
In today's competitive global economy characterized by knowledge acquisition, the concept of knowledge management has become increasingly prevalent in academic and business practices. Knowledge creation is an important factor and remains a source of competitive advantage over knowledge management. Information technology facilitates knowledge…
Heber, S; Varsani, A; Kuhn, S; Girg, A; Kempenaers, B; Briskie, J
2013-02-07
Populations forced through bottlenecks typically lose genetic variation and exhibit inbreeding depression. 'Genetic rescue' techniques that introduce individuals from outbred populations can be highly effective in reversing the deleterious effects of inbreeding, but have limited application for the majority of endangered species, which survive only in a few bottlenecked populations. We tested the effectiveness of using highly inbred populations as donors to rescue two isolated and bottlenecked populations of the South Island robin (Petroica australis). Reciprocal translocations significantly increased heterozygosity and allelic diversity. Increased genetic diversity was accompanied by increased juvenile survival and recruitment, sperm quality, and immunocompetence of hybrid individuals (crosses between the two populations) compared with inbred control individuals (crosses within each population). Our results confirm that the implementation of 'genetic rescue' using bottlenecked populations as donors provides a way of preserving endangered species and restoring their viability when outbred donor populations no longer exist.
The role of partial knowledge in statistical word learning
Fricker, Damian C.; Yu, Chen; Smith, Linda B.
2013-01-01
A critical question about the nature of human learning is whether it is an all-or-none or a gradual, accumulative process. Associative and statistical theories of word learning rely critically on the later assumption: that the process of learning a word's meaning unfolds over time. That is, learning the correct referent for a word involves the accumulation of partial knowledge across multiple instances. Some theories also make an even stronger claim: Partial knowledge of one word–object mapping can speed up the acquisition of other word–object mappings. We present three experiments that test and verify these claims by exposing learners to two consecutive blocks of cross-situational learning, in which half of the words and objects in the second block were those that participants failed to learn in Block 1. In line with an accumulative account, Re-exposure to these mis-mapped items accelerated the acquisition of both previously experienced mappings and wholly new word–object mappings. But how does partial knowledge of some words speed the acquisition of others? We consider two hypotheses. First, partial knowledge of a word could reduce the amount of information required for it to reach threshold, and the supra-threshold mapping could subsequently aid in the acquisition of new mappings. Alternatively, partial knowledge of a word's meaning could be useful for disambiguating the meanings of other words even before the threshold of learning is reached. We construct and compare computational models embodying each of these hypotheses and show that the latter provides a better explanation of the empirical data. PMID:23702980
Knowledge-Acquisition Tool For Expert System
NASA Technical Reports Server (NTRS)
Disbrow, James D.; Duke, Eugene L.; Regenie, Victoria A.
1988-01-01
Digital flight-control systems monitored by computer program that evaluates and recommends. Flight-systems engineers for advanced, high-performance aircraft use knowlege-acquisition tool for expert-system flight-status monitor suppling interpretative data. Interpretative function especially important in time-critical, high-stress situations because it facilitates problem identification and corrective strategy. Conditions evaluated and recommendations made by ground-based engineers having essential knowledge for analysis and monitoring of performances of advanced aircraft systems.
Knowledge Acquisition for Expert Systems in Construction
1988-12-01
following scientific personnel have been closely involved in the execution of this research : Dr R J Allwood Mr A E Bryman Mr C N Cooper Dr J Cullen Mr...alternative methods and should use them flexibly as the position unfolds. This approach has been advocated by other researchers (eg Cordingley - see Diaper...currently engaged in research into methods of knowledge acquisition for expert systems. Although their original focus was on construction industry
NASA Astrophysics Data System (ADS)
Sun, Jie; Li, Zhipeng; Sun, Jian
2015-12-01
Recurring bottlenecks at freeway/expressway are considered as the main cause of traffic congestion in urban traffic system while on-ramp bottlenecks are the most significant sites that may result in congestion. In this paper, the traffic bottleneck characteristics for a simple and typical expressway on-ramp are investigated by the means of simulation modeling under the open boundary condition. In simulations, the running behaviors of each vehicle are described by a car-following model with a calibrated optimal velocity function, and lane changing actions at the merging section are modeled by a novel set of rules. We numerically derive the traffic volume of on-ramp bottleneck under different upstream arrival rates of mainline and ramp flows. It is found that the vehicles from the ramp strongly affect the pass of mainline vehicles and the merging ratio changes with the increasing of ramp vehicle, when the arrival rate of mainline flow is greater than a critical value. In addition, we clarify the dependence of the merging ratio of on-ramp bottleneck on the probability of lane changing and the length of the merging section, and some corresponding intelligent control strategies are proposed in actual traffic application.
Relating GTE and Knowledge-Based Courseware Engineering: Some Epistemological Issues.
ERIC Educational Resources Information Center
De Diana, Italo P. F.; Ladhani, Al-Noor
1998-01-01
Discusses GTE (Generic Tutoring Environment) and knowledge-based courseware engineering from an epistemological point of view and suggests some combination of the two approaches. Topics include intelligent tutoring; courseware authoring; application versus acquisition of knowledge; and domain knowledge. (LRW)
Charting the acquisition of semantic knowledge in a case of developmental amnesia
Gardiner, John M.; Brandt, Karen R.; Baddeley, Alan D.; Vargha-Khadem, Faraneh; Mishkin, Mortimer
2009-01-01
We report the acquisition and recall of novel facts by Jon, a young adult with early onset developmental amnesia whose episodic memory is gravely impaired due to selective bilateral hippocampal damage. Jon succeeded in learning some novel facts but compared with a control group his intertrial retention was impaired during acquisition and, except for the most frequently repeated facts, he was also less accurate in correctly sourcing these facts to the experiment. The results further support the hypothesis that despite a severely compromised episodic memory and hippocampal system, there is nevertheless the capacity to accrue semantic knowledge available to recall. PMID:18589461
Charting the acquisition of semantic knowledge in a case of developmental amnesia.
Gardiner, John M; Brandt, Karen R; Baddeley, Alan D; Vargha-Khadem, Faraneh; Mishkin, Mortimer
2008-09-01
We report the acquisition and recall of novel facts by Jon, a young adult with early onset developmental amnesia whose episodic memory is gravely impaired due to selective bilateral hippocampal damage. Jon succeeded in learning some novel facts but compared with a control group his intertrial retention was impaired during acquisition and, except for the most frequently repeated facts, he was also less accurate in correctly sourcing these facts to the experiment. The results further support the hypothesis that despite a severely compromised episodic memory and hippocampal system, there is nevertheless the capacity to accrue semantic knowledge available to recall.
Free-Space Optical Interconnect Employing VCSEL Diodes
NASA Technical Reports Server (NTRS)
Simons, Rainee N.; Savich, Gregory R.; Torres, Heidi
2009-01-01
Sensor signal processing is widely used on aircraft and spacecraft. The scheme employs multiple input/output nodes for data acquisition and CPU (central processing unit) nodes for data processing. To connect 110 nodes and CPU nodes, scalable interconnections such as backplanes are desired because the number of nodes depends on requirements of each mission. An optical backplane consisting of vertical-cavity surface-emitting lasers (VCSELs), VCSEL drivers, photodetectors, and transimpedance amplifiers is the preferred approach since it can handle several hundred megabits per second data throughput.The next generation of satellite-borne systems will require transceivers and processors that can handle several Gb/s of data. Optical interconnects have been praised for both their speed and functionality with hopes that light can relieve the electrical bottleneck predicted for the near future. Optoelectronic interconnects provide a factor of ten improvement over electrical interconnects.
ERIC Educational Resources Information Center
Özçelik, Öner; Sprouse, Rex A.
2017-01-01
A significant body of theoretically motivated research has addressed the role of Universal Grammar (UG) in the nonnative acquisition of morphosyntax and properties of the syntax-semantics interface, but very little research has addressed the role of phonological principles of UG in nonnative language acquisition. Turkish has a regular and…
In Pursuit of Agile Acquisition: Are We There Yet?
2013-03-01
digital mapping capabilities like Google , 71Microsoft,72 and Wikimapia,73 are readily obtainable in the commercial marketplace. This knowledge...Fox. Defense Acquisition Reform, 14. 69 Ibid., 8. 70 XBRADTC, “Army Acquisition Woes,” Bring the Heat Bring the Stupid , entry posted May 1, 2011...https://xbradtc.wordpress.com/2011/05/01/Army-acquisition-woes/ (accessed on December 5, 2012). 71 Google Maps, http://maps.google.com/maps (accessed
Knowledge acquisition to qualify Unified Medical Language System interconceptual relationships.
Le Duff, F.; Burgun, A.; Cleret, M.; Pouliquen, B.; Barac'h, V.; Le Beux, P.
2000-01-01
Adding automatically relations between concepts from a database to a knowledge base such as the Unified Medical Language System can be very useful to increase the consistency of the latter one. But the transfer of qualified relationships is more interesting. The most important interest of these new acquisitions is that the UMLS became more compliant and medically pertinent to be used in different medical applications. This paper describes the possibility to inherit automatically medical inter-conceptual relationships qualifiers from a disease description included into a database and to integrate them into the UMLS knowledge base. The paper focuses on the transmission of knowledge from a French medical database to an English one. PMID:11079930
Sociolinguistic Variation and Acquisition in Two-Way Language Immersion: Negotiating the Standard
ERIC Educational Resources Information Center
Starr, Rebecca Lurie
2016-01-01
This book investigates the acquisition of sociolinguistic knowledge in the early elementary school years of a Mandarin-English two-way immersion program in the United States. Using ethnographic observation and quantitative analysis of data, the author explores how input from teachers and classmates shapes students' language acquisition. The book…
Insights into Second Language Acquisition Theory and Different Approaches to Language Teaching
ERIC Educational Resources Information Center
Ponniah, Joseph
2010-01-01
This paper attempts to review second language acquisition theory and some of the methods practiced in language classes. The review substantiates that comprehensible input as the crucial determining factor for language acquisition and consciously learned linguistic knowledge can be used only to edit the output of the acquired language sometimes…
Miyashita, Shuhei; Kishino, Hirohisa
2010-02-01
Genetic bottlenecks facilitate the fixation and extinction of variants in populations, and viral populations are no exception to this theory. To examine the existence of genetic bottlenecks in cell-to-cell movement of plant RNA viruses, we prepared constructs for Soil-borne wheat mosaic virus RNA2 vectors carrying two different fluorescent proteins, yellow fluorescent protein (YFP) and cyan fluorescent protein (CFP). Coinoculation of host plant leaves with the two RNA2 vectors and the wild-type RNA1 showed separation of the two vector RNA2s, mostly within seven to nine cell-to-cell movements from individual initially coinfected cells. Our statistical analysis showed that the number of viral RNA genomes establishing infection in adjacent cells after the first cell-to-cell movement from an initially infected cell was 5.97 +/- 0.22 on average and 5.02 +/- 0.29 after the second cell-to-cell movement. These results indicate that plant RNA viruses may generally face narrow genetic bottlenecks in every cell-to-cell movement. Furthermore, our model suggests that, rather than suffering from fitness losses caused by the bottlenecks, the plant RNA viruses are utilizing the repeated genetic bottlenecks as an essential element of rapid selection of their adaptive variants in trans-acting genes or elements to respond to host shifting and changes in the growth conditions of the hosts.
Ha, Duc; Faulx, Michael; Isada, Carlos; Kattan, Michael; Yu, Changhong; Olender, Jeff; Nielsen, Craig; Brateanu, Andrei
2014-01-01
Background The academic half-day (AHD) curriculum is an alternative to the traditional noon conference in graduate medical education, yet little is known regarding its effect on knowledge acquisition and resident satisfaction. Objective We investigated the association between the 2 approaches for delivering the curriculum and knowledge acquisition, as reflected by the Internal Medicine In-Training Examination (IM-ITE) scores and assessed resident learning satisfaction under both curricula. Methods The Cleveland Clinic Internal Medicine Residency Program transitioned from the noon conference to the AHD curriculum in 2011. Covariates for residents enrolled from 2004 to 2011 were age; sex; type of medical degree; United States Medical Licensing Examination Step 1, 2 Clinical Knowledge; and IM-ITE-1 scores. We performed univariable and multivariable linear regressions to investigate the association between covariates and IM-ITE-2 and IM-ITE-3 scores. Residents also were surveyed about their learning satisfaction in both curricula. Results Of 364 residents, 112 (31%) and 252 (69%) were exposed to the AHD and the noon conference curriculum, respectively. In multivariable analyses, the AHD curriculum was associated with higher IM-ITE-3 (regression coefficient, 4.8; 95% confidence interval 2.9–6.6) scores, and residents in the AHD curriculum had greater learning satisfaction compared with the noon conference cohort (Likert, 3.4 versus 3.0; P = .003). Conclusions The AHD curriculum was associated with improvement in resident medical knowledge acquisition and increased learner satisfaction. PMID:24701317
Ha, Duc; Faulx, Michael; Isada, Carlos; Kattan, Michael; Yu, Changhong; Olender, Jeff; Nielsen, Craig; Brateanu, Andrei
2014-03-01
The academic half-day (AHD) curriculum is an alternative to the traditional noon conference in graduate medical education, yet little is known regarding its effect on knowledge acquisition and resident satisfaction. We investigated the association between the 2 approaches for delivering the curriculum and knowledge acquisition, as reflected by the Internal Medicine In-Training Examination (IM-ITE) scores and assessed resident learning satisfaction under both curricula. The Cleveland Clinic Internal Medicine Residency Program transitioned from the noon conference to the AHD curriculum in 2011. Covariates for residents enrolled from 2004 to 2011 were age; sex; type of medical degree; United States Medical Licensing Examination Step 1, 2 Clinical Knowledge; and IM-ITE-1 scores. We performed univariable and multivariable linear regressions to investigate the association between covariates and IM-ITE-2 and IM-ITE-3 scores. Residents also were surveyed about their learning satisfaction in both curricula. Of 364 residents, 112 (31%) and 252 (69%) were exposed to the AHD and the noon conference curriculum, respectively. In multivariable analyses, the AHD curriculum was associated with higher IM-ITE-3 (regression coefficient, 4.8; 95% confidence interval 2.9-6.6) scores, and residents in the AHD curriculum had greater learning satisfaction compared with the noon conference cohort (Likert, 3.4 versus 3.0; P = .003). The AHD curriculum was associated with improvement in resident medical knowledge acquisition and increased learner satisfaction.
Measuring and Visualizing Group Knowledge Elaboration in Online Collaborative Discussions
ERIC Educational Resources Information Center
Zheng, Yafeng; Xu, Chang; Li, Yanyan; Su, You
2018-01-01
Knowledge elaboration plays a critical role in promoting knowledge acquisition and facilitating the retention of target knowledge in online collaborative discussions. Adopting a key-term-based automated analysis approach, we proposed an indicator framework to measure the level of knowledge elaboration in terms of coverage, activation, and…
Chin, Alvin; Helman, Anton; Chan, Teresa M
2018-01-01
Introduction Podcasts and blog posts have gained popularity in Free Open Access Medical education (FOAM). Previous work suggests that podcasts may be useful for knowledge acquisition in undergraduate medical education. However, there remains a paucity of research comparing the two mediums. This study aims to investigate if there are differences in knowledge acquisition and usage conditions by medical students using podcasts and blog posts. Methods Medical students were randomized to either the podcast or blog post group. They completed an initial online assessment of their baseline knowledge on the subject matter. Participants then received access to learning materials and were given four weeks to complete the follow-up assessment on their own time. Independent t-test, paired samples t-test, and a mixed ANOVA (analysis of variance) were conducted to assess knowledge acquisition. An intention-to-teach analysis was used to impute missing data from students lost to follow-up. Simple descriptive statistical data was used to describe media usage conditions. Results Completion of at least one follow-up assessment was comparable (68% podcasts (n = 21/31), 73% blog posts (n = 22/30)). Both groups showed significant improvements in their test scores, with an average 22% improvement for the podcast group and 29% for the blog post group. There was no significant statistical difference in knowledge acquisition between educational modalities overall. Students in the blog post group that completed both post-intervention quizzes showed a larger improvement than the podcast group in the toxicology topic, with similar improvements in the asthma topic. The podcast group tended to engage in multiple activities while using the learning materials (e.g. at least two to three of the following: driving, eating, chores, taking notes, exercising/walking), while the blog readers tended to do fewer activities (e.g. only one of the following: note taking, eating). Conclusion This study suggests that podcasts and blog posts are useful for extracurricular knowledge acquisition by undergraduate medical students with no significant difference between the two modalities. The usage conditions for each type of media differ. PMID:29552428
Population genetic signatures of a climate change driven marine range extension.
Ramos, Jorge E; Pecl, Gretta T; Moltschaniwskyj, Natalie A; Semmens, Jayson M; Souza, Carla A; Strugnell, Jan M
2018-06-22
Shifts in species distribution, or 'range shifts', are one of the most commonly documented responses to ocean warming, with important consequences for the function and structure of ecosystems, and for socio-economic activities. Understanding the genetic signatures of range shifts can help build our knowledge of the capacity of species to establish and persist in colonised areas. Here, seven microsatellite loci were used to examine the population connectivity, genetic structure and diversity of Octopus tetricus, which has extended its distribution several hundred kilometres polewards associated with the southwards extension of the warm East Australian Current along south-eastern Australia. The historical distribution and the range extension zones had significant genetic differences but levels of genetic diversity were comparable. The population in the range extension zone was sub-structured, contained relatively high levels of self-recruitment and was sourced by migrants from along the entire geographic distribution. Genetic bottlenecks and changes in population size were detected throughout the range extension axis. Persistent gene flow from throughout the historical zone and moderate genetic diversity may buffer the genetic bottlenecks and favour the range extension of O. tetricus. These characteristics may aid adaptation, establishment, and long-term persistence of the population in the range extension zone.
Lessons from acute HIV infection.
Robb, Merlin L; Ananworanich, Jintanat
2016-11-01
Understanding the characteristics of transmission during acute HIV infection (AHI) may inform targets for vaccine-induced immune interdiction. Individuals treated in AHI with a small HIV reservoir size may be ideal candidates for therapeutic HIV vaccines aiming for HIV remission (i.e. viremic control after treatment interruption). The AHI period is brief and peak viremia predicts a viral set point that occurs 4-5 weeks following infection. Robust HIV-specific CD8 T-cell responses lower viral set points. Phylogenetic analyses of founder viruses demonstrated unique bottleneck selections and specific genetic signatures to optimize for high-fitness variants and successful transmission events. HIV clades, route of transmission and the presence of minor variants may affect vaccine protection. Antiretroviral treatment in AHI results in smaller HIV reservoir size, better CD4 T-cell recovery and fewer virus escapes. The knowledge of untreated and treated AHI informs the development of vaccines, in that preventive vaccines will require broad coverage for multiple clades and antigenic variants associated with unique bottleneck selections. Vaccines that help the host to control viremia could minimize onward transmission. Therapeutic HIV vaccines aimed at HIV remission should be studied in early-treated individuals who have few or no viral escape mutants and a more preserved immune system.
Seitz, Max W; Haux, Christian; Knaup, Petra; Schubert, Ingrid; Listl, Stefan
2018-01-01
Associations between dental and chronic-systemic diseases were observed frequently in medical research, however the findings of this research have so far found little relevance in everyday clinical treatment. Major problems are the assessment of evidence for correlations between such diseases and how to integrate current medical knowledge into the intersectoral care of dentists and general practitioners. On the example of dental and chronic-systemic diseases, the Dent@Prevent project develops an interdisciplinary decision support system (DSS), which provides the specialists with information relevant for the treatment of such cases. To provide the physicians with relevant medical knowledge, a mixed-methods approach is developed to acquire the knowledge in an evidence-oriented way. This procedure includes a literature review, routine data analyses, focus groups of dentists and general practitioners as well as the identification and integration of applicable guidelines and Patient Reported Measures (PRMs) into the treatment process. The developed mixed methods approach for an evidence-oriented knowledge acquisition indicates to be applicable and supportable for interdisciplinary projects. It can raise the systematic quality of the knowledge-acquisition process and can be applicable for an evidence-based system development. Further research is necessary to assess the impact on patient care and to evaluate possible applicability in other interdisciplinary areas.
Navarrete, Jairo A; Dartnell, Pablo
2017-08-01
Category Theory, a branch of mathematics, has shown promise as a modeling framework for higher-level cognition. We introduce an algebraic model for analogy that uses the language of category theory to explore analogy-related cognitive phenomena. To illustrate the potential of this approach, we use this model to explore three objects of study in cognitive literature. First, (a) we use commutative diagrams to analyze an effect of playing particular educational board games on the learning of numbers. Second, (b) we employ a notion called coequalizer as a formal model of re-representation that explains a property of computational models of analogy called "flexibility" whereby non-similar representational elements are considered matches and placed in structural correspondence. Finally, (c) we build a formal learning model which shows that re-representation, language processing and analogy making can explain the acquisition of knowledge of rational numbers. These objects of study provide a picture of acquisition of numerical knowledge that is compatible with empirical evidence and offers insights on possible connections between notions such as relational knowledge, analogy, learning, conceptual knowledge, re-representation and procedural knowledge. This suggests that the approach presented here facilitates mathematical modeling of cognition and provides novel ways to think about analogy-related cognitive phenomena.
2017-01-01
Category Theory, a branch of mathematics, has shown promise as a modeling framework for higher-level cognition. We introduce an algebraic model for analogy that uses the language of category theory to explore analogy-related cognitive phenomena. To illustrate the potential of this approach, we use this model to explore three objects of study in cognitive literature. First, (a) we use commutative diagrams to analyze an effect of playing particular educational board games on the learning of numbers. Second, (b) we employ a notion called coequalizer as a formal model of re-representation that explains a property of computational models of analogy called “flexibility” whereby non-similar representational elements are considered matches and placed in structural correspondence. Finally, (c) we build a formal learning model which shows that re-representation, language processing and analogy making can explain the acquisition of knowledge of rational numbers. These objects of study provide a picture of acquisition of numerical knowledge that is compatible with empirical evidence and offers insights on possible connections between notions such as relational knowledge, analogy, learning, conceptual knowledge, re-representation and procedural knowledge. This suggests that the approach presented here facilitates mathematical modeling of cognition and provides novel ways to think about analogy-related cognitive phenomena. PMID:28841643
Human Processing of Knowledge from Texts: Acquisition, Integration, and Reasoning
1979-06-01
comprehension. Norwood, N.J.: Ablex, 1977. Craik , F.I.M., and Lockhart , R. S. Levels of processing : for memory research. Journal of Verbal Learning A...Table 5.9 presents summary data regarding the performance levels and memory and search processes of individual subjects. The first row in Table 5.9...R-2256-ARP A June 1979 ARPA Order No.: 189-1 9020 Cybernetics Technology Human Processing of Knowledge from Texts: Acquisition, Integration, and
ERIC Educational Resources Information Center
Beckmann, Jens F.; Goode, Natassia
2014-01-01
Previous research has found that embedding a problem into a familiar context does not necessarily confer an advantage over a novel context in the acquisition of new knowledge about a complex, dynamic system. In fact, it has been shown that a semantically familiar context can be detrimental to knowledge acquisition. This has been described as the…
A middle man approach to knowledge acquisition in expert systems
NASA Technical Reports Server (NTRS)
Jordan, Janice A.; Lin, Min-Jin; Mayer, Richard J.; Sterle, Mark E.
1990-01-01
The Weed Control Advisor (WCA) is a robust expert system that has been successfully implemented on an IBM AT class microcomputer in CLIPS. The goal of the WCA was to demonstrate the feasibility of providing an economical, efficient, user friendly system through which Texas rice producers could obtain expert level knowledge regarding herbicide application for weed control. During the development phase of the WCA, an improved knowledge acquisition method which we call the Middle Man Approach (MMA) was applied to facilitate the communication process between the domain experts and the knowledge engineer. The MMA served to circumvent the problems associated with the more traditional forms of knowledge acquisition by placing the Middle Man, a semi-expert in the problem domain with some computer expertise, at the site of system development. The middle man was able to contribute to system development in two major ways. First, the Middle Man had experience working in rice production and could assume many of the responsibilities normally performed by the domain experts such as explaining the background of the problem domain and determining the important relations. Second, the Middle Man was familiar with computers and worked closely with the system developers to update the rules after the domain experts reviewed the prototype, contribute to the help menus and explanation portions of the expert system, conduct the testing that is required to insure that the expert system gives the expected results answer questions in a timely way, help the knowledge engineer structure the domain knowledge into a useable form, and provide insight into the end user's profile which helped in the development of the simple user friendly interface. The final results were not only that both time expended and costs were greatly reduced by using the MMA, but the quality of the system was improved. This papa will introduce the WCA system and then discuss traditional knowledge acquisition along with some of the problems often associated with it, the MMA methodology, and its application to the WCA development.
The Case for a Gaian Bottleneck: The Biology of Habitability.
Chopra, Aditya; Lineweaver, Charles H
2016-01-01
The prerequisites and ingredients for life seem to be abundantly available in the Universe. However, the Universe does not seem to be teeming with life. The most common explanation for this is a low probability for the emergence of life (an emergence bottleneck), notionally due to the intricacies of the molecular recipe. Here, we present an alternative Gaian bottleneck explanation: If life emerges on a planet, it only rarely evolves quickly enough to regulate greenhouse gases and albedo, thereby maintaining surface temperatures compatible with liquid water and habitability. Such a Gaian bottleneck suggests that (i) extinction is the cosmic default for most life that has ever emerged on the surfaces of wet rocky planets in the Universe and (ii) rocky planets need to be inhabited to remain habitable. In the Gaian bottleneck model, the maintenance of planetary habitability is a property more associated with an unusually rapid evolution of biological regulation of surface volatiles than with the luminosity and distance to the host star.
ERIC Educational Resources Information Center
Zascerinska, Jelena
2010-01-01
Introduction. The use of three-five languages is of the greatest importance in order to form varied cooperative networks for the creation of new knowledge. Aim of the paper is to analyze the synergy between language acquisition and language learning. Materials and Methods. The search for the synergy between language acquisition and language…
Young children's acquisition of knowledge about the Earth: A longitudinal study.
Hannust, Triin; Kikas, Eve
2010-10-01
This longitudinal study examined the acquisition of early knowledge of astronomy to determine whether children's knowledge at any point in time is consistent with a naive "mental model." Children were first assessed by means of open questions and drawing tasks at 2 and 3 years of age (N=143). The knowledge was reassessed over the course of the following 3 years. The results showed that although a few indications of naive mental models were found, in most cases young children's knowledge was fragmented and accurate knowledge was often expressed alongside inaccurate/synthetic ideas. Furthermore, it was shown that children need to know scientific facts before they start taking the global perspective when describing the world and, when faced with ambiguous open questions, children often experience difficulties that can induce them to change the types of answers they provide. Copyright 2010 Elsevier Inc. All rights reserved.
Nicholson, Anita; Tobin, Mary
2006-01-01
This presentation will discuss coupling commercial and customized computer-supported teaching aids to provide BSN nursing students with a friendly customer-centered self-study approach to psychomotor skill acquisition.
Exascale Storage Systems the SIRIUS Way
NASA Astrophysics Data System (ADS)
Klasky, S. A.; Abbasi, H.; Ainsworth, M.; Choi, J.; Curry, M.; Kurc, T.; Liu, Q.; Lofstead, J.; Maltzahn, C.; Parashar, M.; Podhorszki, N.; Suchyta, E.; Wang, F.; Wolf, M.; Chang, C. S.; Churchill, M.; Ethier, S.
2016-10-01
As the exascale computing age emerges, data related issues are becoming critical factors that determine how and where we do computing. Popular approaches used by traditional I/O solution and storage libraries become increasingly bottlenecked due to their assumptions about data movement, re-organization, and storage. While, new technologies, such as “burst buffers”, can help address some of the short-term performance issues, it is essential that we reexamine the underlying storage and I/O infrastructure to effectively support requirements and challenges at exascale and beyond. In this paper we present a new approach to the exascale Storage System and I/O (SSIO), which is based on allowing users to inject application knowledge into the system and leverage this knowledge to better manage, store, and access large data volumes so as to minimize the time to scientific insights. Central to our approach is the distinction between the data, metadata, and the knowledge contained therein, transferred from the user to the system by describing “utility” of data as it ages.
Connolly, Kiah; Beier, Lancelot; Langdorf, Mark I; Anderson, Craig L; Fox, John C
2015-01-01
Our objective was to evaluate the effectiveness of hands-on training at a bedside ultrasound (US) symposium ("Ultrafest") to improve both clinical knowledge and image acquisition skills of medical students. Primary outcome measure was improvement in multiple choice questions on pulmonary or Focused Assessment with Sonography in Trauma (FAST) US knowledge. Secondary outcome was improvement in image acquisition for either pulmonary or FAST. Prospective cohort study of 48 volunteers at "Ultrafest," a free symposium where students received five contact training hours. Students were evaluated before and after training for proficiency in either pulmonary US or FAST. Proficiency was assessed by clinical knowledge through written multiple-choice exam, and clinical skills through accuracy of image acquisition. We used paired sample t-tests with students as their own controls. Pulmonary knowledge scores increased by a mean of 10.1 points (95% CI [8.9-11.3], p<0.00005), from 8.4 to a posttest average of 18.5/21 possible points. The FAST knowledge scores increased by a mean of 7.5 points (95% CI [6.3-8.7] p<0.00005), from 8.1 to a posttest average of 15.6/21. We analyzed clinical skills data on 32 students. The mean score was 1.7 pretest and 4.7 posttest of 12 possible points. Mean improvement was 3.0 points (p<0.00005) overall, 3.3 (p=0.0001) for FAST, and 2.6 (p=0.003) for the pulmonary US exam. This study suggests that a symposium on US can improve clinical knowledge, but is limited in achieving image acquisition for pulmonary and FAST US assessments. US training external to official medical school curriculum may augment students' education.
Genome-wide signatures of population bottlenecks and diversifying selection in European wolves
Pilot, M; Greco, C; vonHoldt, B M; Jędrzejewska, B; Randi, E; Jędrzejewski, W; Sidorovich, V E; Ostrander, E A; Wayne, R K
2014-01-01
Genomic resources developed for domesticated species provide powerful tools for studying the evolutionary history of their wild relatives. Here we use 61K single-nucleotide polymorphisms (SNPs) evenly spaced throughout the canine nuclear genome to analyse evolutionary relationships among the three largest European populations of grey wolves in comparison with other populations worldwide, and investigate genome-wide effects of demographic bottlenecks and signatures of selection. European wolves have a discontinuous range, with large and connected populations in Eastern Europe and relatively smaller, isolated populations in Italy and the Iberian Peninsula. Our results suggest a continuous decline in wolf numbers in Europe since the Late Pleistocene, and long-term isolation and bottlenecks in the Italian and Iberian populations following their divergence from the Eastern European population. The Italian and Iberian populations have low genetic variability and high linkage disequilibrium, but relatively few autozygous segments across the genome. This last characteristic clearly distinguishes them from populations that underwent recent drastic demographic declines or founder events, and implies long-term bottlenecks in these two populations. Although genetic drift due to spatial isolation and bottlenecks seems to be a major evolutionary force diversifying the European populations, we detected 35 loci that are putatively under diversifying selection. Two of these loci flank the canine platelet-derived growth factor gene, which affects bone growth and may influence differences in body size between wolf populations. This study demonstrates the power of population genomics for identifying genetic signals of demographic bottlenecks and detecting signatures of directional selection in bottlenecked populations, despite their low background variability. PMID:24346500
Cancer Genome Interpreter annotates the biological and clinical relevance of tumor alterations.
Tamborero, David; Rubio-Perez, Carlota; Deu-Pons, Jordi; Schroeder, Michael P; Vivancos, Ana; Rovira, Ana; Tusquets, Ignasi; Albanell, Joan; Rodon, Jordi; Tabernero, Josep; de Torres, Carmen; Dienstmann, Rodrigo; Gonzalez-Perez, Abel; Lopez-Bigas, Nuria
2018-03-28
While tumor genome sequencing has become widely available in clinical and research settings, the interpretation of tumor somatic variants remains an important bottleneck. Here we present the Cancer Genome Interpreter, a versatile platform that automates the interpretation of newly sequenced cancer genomes, annotating the potential of alterations detected in tumors to act as drivers and their possible effect on treatment response. The results are organized in different levels of evidence according to current knowledge, which we envision can support a broad range of oncology use cases. The resource is publicly available at http://www.cancergenomeinterpreter.org .
Szameitat, André J.; Vanloo, Azonya; Müller, Hermann J.
2016-01-01
Human information processing suffers from severe limitations in parallel processing. In particular, when required to respond to two stimuli in rapid succession, processing bottlenecks may appear at central and peripheral stages of task processing. Importantly, it has been suggested that executive functions are needed to resolve the interference arising at such bottlenecks. The aims of the present study were to test whether central attentional limitations (i.e., bottleneck at the decisional response selection stage) as well as peripheral limitations (i.e., bottleneck at response initiation) both demand executive functions located in the lateral prefrontal cortex. For this, we re-analyzed two previous studies, in which a total of 33 participants performed a dual-task according to the paradigm of the psychological refractory period (PRP) during functional magnetic resonance imaging (fMRI). In one study (N = 17), the PRP task consisted of two two-choice response tasks known to suffer from a central bottleneck (CB group). In the other study (N = 16), the PRP task consisted of two simple-response tasks known to suffer from a peripheral bottleneck (PB group). Both groups showed considerable dual-task costs in form of slowing of the second response in the dual-task (PRP effect). Imaging results are based on the subtraction of both single-tasks from the dual-task within each group. In the CB group, the bilateral middle frontal gyri and inferior frontal gyri were activated. Higher activation in these areas was associated with lower dual-task costs. In the PB group, the right middle frontal and inferior frontal gyrus (IFG) were activated. Here, higher activation was associated with higher dual-task costs. In conclusion we suggest that central and peripheral bottlenecks both demand executive functions located in lateral prefrontal cortices (LPFC). Differences between the CB and PB groups with respect to the exact prefrontal areas activated and the correlational patterns suggest that the executive functions resolving interference at least partially differ between the groups. PMID:27014044
Schmalhofer, F J; Tschaitschian, B
1998-11-01
In this paper, we perform a cognitive analysis of knowledge discovery processes. As a result of this analysis, the construction-integration theory is proposed as a general framework for developing cooperative knowledge evolution systems. We thus suggest that for the acquisition of new domain knowledge in medicine, one should first construct pluralistic views on a given topic which may contain inconsistencies as well as redundancies. Only thereafter does this knowledge become consolidated into a situation-specific circumscription and the early inconsistencies become eliminated. As a proof for the viability of such knowledge acquisition processes in medicine, we present the IDEAS system, which can be used for the intelligent documentation of adverse events in clinical studies. This system provides a better documentation of the side-effects of medical drugs. Thereby, knowledge evolution occurs by achieving consistent explanations in increasingly larger contexts (i.e., more cases and more pharmaceutical substrates). Finally, it is shown how prototypes, model-based approaches and cooperative knowledge evolution systems can be distinguished as different classes of knowledge-based systems.
Acquisition, representation and rule generation for procedural knowledge
NASA Technical Reports Server (NTRS)
Ortiz, Chris; Saito, Tim; Mithal, Sachin; Loftin, R. Bowen
1991-01-01
Current research into the design and continuing development of a system for the acquisition of procedural knowledge, its representation in useful forms, and proposed methods for automated C Language Integrated Production System (CLIPS) rule generation is discussed. The Task Analysis and Rule Generation Tool (TARGET) is intended to permit experts, individually or collectively, to visually describe and refine procedural tasks. The system is designed to represent the acquired knowledge in the form of graphical objects with the capacity for generating production rules in CLIPS. The generated rules can then be integrated into applications such as NASA's Intelligent Computer Aided Training (ICAT) architecture. Also described are proposed methods for use in translating the graphical and intermediate knowledge representations into CLIPS rules.
The Effects of Transferred Vocabulary Knowledge on the Development of L2 Reading Proficiency.
ERIC Educational Resources Information Center
Koda, Keiko
1989-01-01
Examination of the effects of transferred vocabulary knowledge on college students' (N=24) acquisition of Japanese linguistic knowledge, verbal processing skills, and reading comprehension indicated that vocabulary knowledge was most highly correlated with reading comprehension. This initial advantage magnified its effects over time as task…
ERIC Educational Resources Information Center
Li, Yufeng; Xiong, Jianwen
2012-01-01
Scientific inquiry is one of the science curriculum content, "Scientific inquiry" - Pedagogical Content Knowledge is the face of scientific inquiry and teachers - of course pedagogical content knowledge and scientific inquiry a teaching practice with more direct expertise. Pre-service teacher training phase of acquisition of knowledge is…
Knowledge Management, Human Resource Management, and Higher Education: A Theoretical Model
ERIC Educational Resources Information Center
Brewer, Peggy D.; Brewer, Kristen L.
2010-01-01
Much has been written on the importance of knowledge management, the challenges facing organizations, and the important human resource management activities involved in assuring the acquisition and transfer of knowledge. Higher business education plays an important role in preparing students to assume the knowledge management and human resource…
Enabling Security, Stability, Transition, and Reconstruction Operations through Knowledge Management
2009-03-18
strategy. Overall, the cultural barriers to knowledge sharing center on knowledge creation and capture. The primary barrier to knowledge sharing is lack ... Lacking a shared identity decreases the likelihood of knowledge sharing, which is essential to effective collaboration.84 Related to collaboration...to adapt, develop, and change based on experience-derived knowledge.90 A second cultural barrier to knowledge acquisition is the lack receptiveness
The Exploration-Exploitation Dilemma: A Multidisciplinary Framework
Berger-Tal, Oded; Meron, Ehud; Saltz, David
2014-01-01
The trade-off between the need to obtain new knowledge and the need to use that knowledge to improve performance is one of the most basic trade-offs in nature, and optimal performance usually requires some balance between exploratory and exploitative behaviors. Researchers in many disciplines have been searching for the optimal solution to this dilemma. Here we present a novel model in which the exploration strategy itself is dynamic and varies with time in order to optimize a definite goal, such as the acquisition of energy, money, or prestige. Our model produced four very distinct phases: Knowledge establishment, Knowledge accumulation, Knowledge maintenance, and Knowledge exploitation, giving rise to a multidisciplinary framework that applies equally to humans, animals, and organizations. The framework can be used to explain a multitude of phenomena in various disciplines, such as the movement of animals in novel landscapes, the most efficient resource allocation for a start-up company, or the effects of old age on knowledge acquisition in humans. PMID:24756026
ERIC Educational Resources Information Center
Adi-Japha, Esther; Fox, Orly; Karni, Avi
2011-01-01
Individuals with ADHD often show performance deficits in motor tasks. It is not clear, however, whether this reflects less effective acquisition of skill (procedural knowledge), or deficient consolidation into long-term memory, in ADHD. The aim of the study was to compare the acquisition of skilled motor performance, the expression of…
2015-01-01
Background An estimated two-thirds of the world's 2.7 million newborn deaths could be prevented with quality care at birth and during the postnatal period. Basic Newborn Care (BNC) is part of the solution and includes hygienic birth and newborn care practices including cord care, thermal care, and early and exclusive breastfeeding. Timely provision of resuscitation if needed is also critical to newborn survival. This paper describes health system barriers to BNC and neonatal resuscitation and proposes solutions to scale up evidence-based strategies. Methods The maternal and newborn bottleneck analysis tool was applied by 12 countries in Africa and Asia as part of the Every Newborn Action Plan process. Country workshops engaged technical experts to complete the survey tool, which is designed to synthesise and grade health system "bottlenecks" that hinder the scale up of maternal-newborn intervention packages. We used quantitative and qualitative methods to analyse the bottleneck data, combined with literature review, to present priority bottlenecks and actions relevant to different health system building blocks for BNC and neonatal resuscitation. Results Eleven of the 12 countries provided grading data. Overall, bottlenecks were graded more severely for resuscitation. The most severely graded bottlenecks for BNC were health workforce (8 of 11 countries), health financing (9 out of 11) and service delivery (7 out of 9); and for neonatal resuscitation, workforce (9 out of 10), essential commodities (9 out of 10) and service delivery (8 out of 10). Country teams from Africa graded bottlenecks overall more severely. Improving workforce performance, availability of essential commodities, and well-integrated health service delivery were the key solutions proposed. Conclusions BNC was perceived to have the least health system challenges among the seven maternal and newborn intervention packages assessed. Although neonatal resuscitation bottlenecks were graded more severe than for BNC, similarities particularly in the workforce and service delivery building blocks highlight the inextricable link between the two interventions and the need to equip birth attendants with requisite skills and commodities to assess and care for every newborn. Solutions highlighted by country teams include ensuring more investment to improve workforce performance and distribution, especially numbers of skilled birth attendants, incentives for placement in challenging settings, and skills-based training particularly for neonatal resuscitation. PMID:26391000
ERIC Educational Resources Information Center
Bernacki, Matthew
2010-01-01
This study examined how learners construct textbase and situation model knowledge in hypertext computer-based learning environments (CBLEs) and documented the influence of specific self-regulated learning (SRL) tactics, prior knowledge, and characteristics of the learner on posttest knowledge scores from exposure to a hypertext. A sample of 160…
Kerner, Boris S; Klenov, Sergey L; Schreckenberg, Michael
2014-05-01
Physical features of induced phase transitions in a metastable free flow at an on-ramp bottleneck in three-phase and two-phase cellular automaton (CA) traffic-flow models have been revealed. It turns out that at given flow rates at the bottleneck, to induce a moving jam (F → J transition) in the metastable free flow through the application of a time-limited on-ramp inflow impulse, in both two-phase and three-phase CA models the same critical amplitude of the impulse is required. If a smaller impulse than this critical one is applied, neither F → J transition nor other phase transitions can occur in the two-phase CA model. We have found that in contrast with the two-phase CA model, in the three-phase CA model, if the same smaller impulse is applied, then a phase transition from free flow to synchronized flow (F → S transition) can be induced at the bottleneck. This explains why rather than the F → J transition, in the three-phase theory traffic breakdown at a highway bottleneck is governed by an F → S transition, as observed in real measured traffic data. None of two-phase traffic-flow theories incorporates an F → S transition in a metastable free flow at the bottleneck that is the main feature of the three-phase theory. On the one hand, this shows the incommensurability of three-phase and two-phase traffic-flow theories. On the other hand, this clarifies why none of the two-phase traffic-flow theories can explain the set of fundamental empirical features of traffic breakdown at highway bottlenecks.
Budget process bottlenecks for immunization financing in the Democratic Republic of the Congo (DRC).
Le Gargasson, Jean-Bernard; Mibulumukini, Benoît; Gessner, Bradford D; Colombini, Anaïs
2014-02-19
In Democratic Republic of the Congo (DRC), the availability of domestic resources for the immunization program is limited and relies mostly on external donor support. DRC has introduced a series of reforms to move the country toward performance-based management and program budgets. The objectives of the study were to: (i) describe the budget process norm, (ii) analyze the budget process in practice and associated bottlenecks at each of its phases, and (iii) collect suggestions made by the actors involved to improve the situation. Quantitative and qualitative data were collected through: a review of published and gray literature, and individual interviews. Bottlenecks in the budget process and disbursement of funds for immunization are one of the causes of limited domestic resources for the program. Critical bottlenecks include: excessive use of off-budget procedures; limited human resources and capacity; lack of motivation; interference from ministries with the standard budget process; dependency toward the development partner's disbursements schedule; and lack of budget implementation tracking. Results show that the health sector's mobilization rate was 59% in 2011. For the credit line specific to immunization program activities, the mobilization rate for the national Expanded Program for Immunization (EPI) was 26% in 2011 and 43% for vaccines (2010). The main bottleneck for the EPI budget line (2011) and vaccine budget line (2011) occurs at the authorization phase. Budget process bottlenecks identified in the analysis lead to a low mobilization rate for the immunization program. The bottlenecks identified show that a poor flow of funds causes an insufficient percentage of already allocated resources to reach various health system levels. Copyright © 2014 Elsevier Ltd. All rights reserved.
Ramstad, Kristina M.; Woody, Carol Ann; Habicht, Chris; Sage, G. Kevin; Seeb, James E.; Allendorf, Fred W.
2007-01-01
Genetic bottleneck effects can reduce genetic variation, persistence probability, and evolutionary potential of populations. Previous microsatellite analysis suggested a bottleneck associated with a common founding of sock-eye salmon Oncorhynchus nerka populations of Lake Clark, Alaska, about 100 to 400 generations ago. The common foundingevent occurred after the last glacial recession and resulted in reduced allelic diversity and strong divergence of Lake Clarksockeye salmon relative to neighboring Six Mile Lake and LakeIliamna populations. Here we used two additional genetic marker types (allozymes and mtDNA) to examine these patterns further. Allozyme and mtDNA results were congruent with the microsatellite data in suggesting a common founder event in LakeClark sockeye salmon and confirmed the divergence of Lake Clarkpopulations from neighboring Six Mile Lake and Lake Iliamna populations. The use of multiple marker types provided better understanding of the bottleneck in Lake Clark. For example, the Sucker Bay Lake population had an exceptionally severe reduction in allelic diversity at microsatellite loci, but not at mtDNA. This suggests that the reduced microsatellite variation in Sucker Bay Lake fish is due to consistently smaller effective population size than other Lake Clark populations, rather than a more acute or additional bottleneck since founding. Caution is urged in using reduced heterozygosity as a measure of genetic bottleneck effects because stochastic variance among loci resulted in an overall increase in allozyme heterozygosity within bottlenecked Lake Clark populations. However, heterozygosity excess, which assesses heterozygosity relative to allelic variation, detected genetic bottleneck effects in both allozyme and microsatellite loci.
Xu, Zheng; Wang, Sheng; Li, Yeqing; Zhu, Feiyun; Huang, Junzhou
2018-02-08
The most recent history of parallel Magnetic Resonance Imaging (pMRI) has in large part been devoted to finding ways to reduce acquisition time. While joint total variation (JTV) regularized model has been demonstrated as a powerful tool in increasing sampling speed for pMRI, however, the major bottleneck is the inefficiency of the optimization method. While all present state-of-the-art optimizations for the JTV model could only reach a sublinear convergence rate, in this paper, we squeeze the performance by proposing a linear-convergent optimization method for the JTV model. The proposed method is based on the Iterative Reweighted Least Squares algorithm. Due to the complexity of the tangled JTV objective, we design a novel preconditioner to further accelerate the proposed method. Extensive experiments demonstrate the superior performance of the proposed algorithm for pMRI regarding both accuracy and efficiency compared with state-of-the-art methods.
Note: Fully integrated 3.2 Gbps quantum random number generator with real-time extraction
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhang, Xiao-Guang; Nie, You-Qi; Liang, Hao
2016-07-15
We present a real-time and fully integrated quantum random number generator (QRNG) by measuring laser phase fluctuations. The QRNG scheme based on laser phase fluctuations is featured for its capability of generating ultra-high-speed random numbers. However, the speed bottleneck of a practical QRNG lies on the limited speed of randomness extraction. To close the gap between the fast randomness generation and the slow post-processing, we propose a pipeline extraction algorithm based on Toeplitz matrix hashing and implement it in a high-speed field-programmable gate array. Further, all the QRNG components are integrated into a module, including a compact and actively stabilizedmore » interferometer, high-speed data acquisition, and real-time data post-processing and transmission. The final generation rate of the QRNG module with real-time extraction can reach 3.2 Gbps.« less
Exploiting Artificial Intelligence for Analysis and Data Selection on-board the Puerto Rico CubeSat
NASA Astrophysics Data System (ADS)
Bergman, J. E. S.; Bruhn, F.; Funk, P.; Isham, B.; Rincón-Charris, A. A.; Capo-Lugo, P.; Åhlén, L.
2015-10-01
CubeSat missions are constrained by the limited resources provided by the platform. Many payload providers have learned to cope with the low mass and power but the poor telemetry allocation remains a bottleneck. In the end, it is the data delivered to ground which determines the value of the mission. However, transmitting more data does not necessarily guarantee high value, since the value also depends on the data quality. By exploiting fast on-board computing and efficient artificial intelligence (AI) algorithms for analysis and data selection one could optimize the usage of the telemetry link and so increase the value of the mission. In a pilot project, we attempt to do this on the Puerto Rico CubeSat, where science objectives include the acquisition of space weather data to aid better understanding of the Sun to Earth connection.
Gai, Jiading; Obeid, Nady; Holtrop, Joseph L.; Wu, Xiao-Long; Lam, Fan; Fu, Maojing; Haldar, Justin P.; Hwu, Wen-mei W.; Liang, Zhi-Pei; Sutton, Bradley P.
2013-01-01
Several recent methods have been proposed to obtain significant speed-ups in MRI image reconstruction by leveraging the computational power of GPUs. Previously, we implemented a GPU-based image reconstruction technique called the Illinois Massively Parallel Acquisition Toolkit for Image reconstruction with ENhanced Throughput in MRI (IMPATIENT MRI) for reconstructing data collected along arbitrary 3D trajectories. In this paper, we improve IMPATIENT by removing computational bottlenecks by using a gridding approach to accelerate the computation of various data structures needed by the previous routine. Further, we enhance the routine with capabilities for off-resonance correction and multi-sensor parallel imaging reconstruction. Through implementation of optimized gridding into our iterative reconstruction scheme, speed-ups of more than a factor of 200 are provided in the improved GPU implementation compared to the previous accelerated GPU code. PMID:23682203
Churski, Marcin; Bubnicki, Jakub W; Jędrzejewska, Bogumiła; Kuijper, Dries P J; Cromsigt, Joris P G M
2017-04-01
Plant biomass consumers (mammalian herbivory and fire) are increasingly seen as major drivers of ecosystem structure and function but the prevailing paradigm in temperate forest ecology is still that their dynamics are mainly bottom-up resource-controlled. Using conceptual advances from savanna ecology, particularly the demographic bottleneck model, we present a novel view on temperate forest dynamics that integrates consumer and resource control. We used a fully factorial experiment, with varying levels of ungulate herbivory and resource (light) availability, to investigate how these factors shape recruitment of five temperate tree species. We ran simulations to project how inter- and intraspecific differences in height increment under the different experimental scenarios influence long-term recruitment of tree species. Strong herbivore-driven demographic bottlenecks occurred in our temperate forest system, and bottlenecks were as strong under resource-rich as under resource-poor conditions. Increased browsing by herbivores in resource-rich patches strongly counteracted the increased escape strength of saplings in these patches. This finding is a crucial extension of the demographic bottleneck model which assumes that increased resource availability allows plants to more easily escape consumer-driven bottlenecks. Our study demonstrates that a more dynamic understanding of consumer-resource interactions is necessary, where consumers and plants both respond to resource availability. © 2016 The Authors. New Phytologist © 2016 New Phytologist Trust.
NASA Astrophysics Data System (ADS)
Kahagalage, Sanath; Tordesillas, Antoinette; Nitka, Michał; Tejchman, Jacek
2017-06-01
Using data from discrete element simulations, we develop a data analytics approach using network flow theory to study force transmission and failure in a `dog-bone' concrete specimen submitted to uniaxial tension. With this approach, we establish the extent to which the bottlenecks, i.e., a subset of contacts that impedes flow and are prone to becoming overloaded, can predict the location of the ultimate macro-crack. At the heart of this analysis is a capacity function that quantifies, in relative terms, the maximum force that can be transmitted through the different contacts or edges in the network. Here we set this function to be solely governed by the size of the contact area between the deformable spherical grains. During all the initial stages of the loading history, when no bonds are broken, we find the bottlenecks coincide consistently with, and therefore predict, the location of the crack that later forms in the failure regime after peak force. When bonds do start to break, they are spread throughout the specimen: in, near, and far from, the bottlenecks. In one stage leading up to peak force, bonds collectively break in the lower portion of the specimen, momentarily shifting the bottlenecks to this location. Just before and around peak force, however, the bottlenecks return to their original location and remain there until the macro-crack emerges right along the bottlenecks.
Self-organized phenomena of pedestrian counterflow through a wide bottleneck in a channel
NASA Astrophysics Data System (ADS)
Dong, Li-Yun; Lan, Dong-Kai; Li, Xiang
2016-09-01
The pedestrian counterflow through a bottleneck in a channel shows a variety of flow patterns due to self-organization. In order to reveal the underlying mechanism, a cellular automaton model was proposed by incorporating the floor field and the view field which reflects the global information of the studied area and local interactions with others. The presented model can well reproduce typical collective behaviors, such as lane formation. Numerical simulations were performed in the case of a wide bottleneck and typical flow patterns at different density ranges were identified as rarefied flow, laminar flow, interrupted bidirectional flow, oscillatory flow, intermittent flow, and choked flow. The effects of several parameters, such as the size of view field and the width of opening, on the bottleneck flow are also analyzed in detail. The view field plays a vital role in reproducing self-organized phenomena of pedestrian. Numerical results showed that the presented model can capture key characteristics of bottleneck flows. Project supported by the National Basic Research Program of China (Grant No. 2012CB725404) and the National Natural Science Foundation of China (Grant Nos. 11172164 and 11572184).
An advanced artificial intelligence tool for menu design.
Khan, Abdus Salam; Hoffmann, Achim
2003-01-01
The computer-assisted menu design still remains a difficult task. Usually knowledge that aids in menu design by a computer is hard-coded and because of that a computerised menu planner cannot handle the menu design problem for an unanticipated client. To address this problem we developed a menu design tool, MIKAS (menu construction using incremental knowledge acquisition system), an artificial intelligence system that allows the incremental development of a knowledge-base for menu design. We allow an incremental knowledge acquisition process in which the expert is only required to provide hints to the system in the context of actual problem instances during menu design using menus stored in a so-called Case Base. Our system incorporates Case-Based Reasoning (CBR), an Artificial Intelligence (AI) technique developed to mimic human problem solving behaviour. Ripple Down Rules (RDR) are a proven technique for the acquisition of classification knowledge from expert directly while they are using the system, which complement CBR in a very fruitful way. This combination allows the incremental improvement of the menu design system while it is already in routine use. We believe MIKAS allows better dietary practice by leveraging a dietitian's skills and expertise. As such MIKAS has the potential to be helpful for any institution where dietary advice is practised.
Power amplification for petawatt Ti: Sapphire lasers: New strategies for high fluence pumping
NASA Astrophysics Data System (ADS)
Canova, F.; Chambaret, J.-P.
2006-06-01
One of the major bottlenecks when we pump large Ti:Sapphire crystals, to reach Petawatt level laser amplification, is the careful control of the spatial energy distribution of Nd:Glass pump lasers. Commercially available nanosecond Nd:Glass and Nd:YAG lasers exhibit poor spatial profile quality especially in the near and in the intermediate field, which can lead to local hot spots, responsible of damages in crystals, and parasitic transverse lasing enhancement, strongly dependent on the profile of the pump beam . For these reasons, it is mandatory to keep the pump beam intensity profile as flat as possible on the pumped crystal. To guarantee the best pumping conditions we are investigating the combined use of DOE (diffractive optical elements) and optical smoothing techniques. In parallel we are starting a study on laser induced damages mechanisms in crystal. With DOE and microlens arrays we plan to guarantee to the beam a supergaussian shape. Simulation and first experiments with both optical systems show that a flat top spatial profile with less than 10% fluctuations and a 8th order supergaussian is possible with the present technology.Optical smoothing will keep the beam free of hot spots. We especially focused on the smoothing techniques involving optical fibers. This is the first time to our knowledge that this technique is applied to the pumping beams for Ti:Sapphire systems. A deep study of laser-crystal interaction will allow us to fully understand the damages created by hot spots. The knowledge of the phenomena involved in laser damages on Ti:Sapphire is mandatory to control the pumping processes and thresholds. In conclusion, mixing the advantages of these different approaches to overcome this bottleneck will allow us to amplify in a safety way femtosecond laser beams to the Petawatt level using Ti:Sapphire crystals.
On the Inefficiency of Equilibria in Linear Bottleneck Congestion Games
NASA Astrophysics Data System (ADS)
de Keijzer, Bart; Schäfer, Guido; Telelis, Orestis A.
We study the inefficiency of equilibrium outcomes in bottleneck congestion games. These games model situations in which strategic players compete for a limited number of facilities. Each player allocates his weight to a (feasible) subset of the facilities with the goal to minimize the maximum (weight-dependent) latency that he experiences on any of these facilities. We derive upper and (asymptotically) matching lower bounds on the (strong) price of anarchy of linear bottleneck congestion games for a natural load balancing social cost objective (i.e., minimize the maximum latency of a facility). We restrict our studies to linear latency functions. Linear bottleneck congestion games still constitute a rich class of games and generalize, for example, load balancing games with identical or uniformly related machines with or without restricted assignments.
eFSM--a novel online neural-fuzzy semantic memory model.
Tung, Whye Loon; Quek, Chai
2010-01-01
Fuzzy rule-based systems (FRBSs) have been successfully applied to many areas. However, traditional fuzzy systems are often manually crafted, and their rule bases that represent the acquired knowledge are static and cannot be trained to improve the modeling performance. This subsequently leads to intensive research on the autonomous construction and tuning of a fuzzy system directly from the observed training data to address the knowledge acquisition bottleneck, resulting in well-established hybrids such as neural-fuzzy systems (NFSs) and genetic fuzzy systems (GFSs). However, the complex and dynamic nature of real-world problems demands that fuzzy rule-based systems and models be able to adapt their parameters and ultimately evolve their rule bases to address the nonstationary (time-varying) characteristics of their operating environments. Recently, considerable research efforts have been directed to the study of evolving Tagaki-Sugeno (T-S)-type NFSs based on the concept of incremental learning. In contrast, there are very few incremental learning Mamdani-type NFSs reported in the literature. Hence, this paper presents the evolving neural-fuzzy semantic memory (eFSM) model, a neural-fuzzy Mamdani architecture with a data-driven progressively adaptive structure (i.e., rule base) based on incremental learning. Issues related to the incremental learning of the eFSM rule base are carefully investigated, and a novel parameter learning approach is proposed for the tuning of the fuzzy set parameters in eFSM. The proposed eFSM model elicits highly interpretable semantic knowledge in the form of Mamdani-type if-then fuzzy rules from low-level numeric training data. These Mamdani fuzzy rules define the computing structure of eFSM and are incrementally learned with the arrival of each training data sample. New rules are constructed from the emergence of novel training data and obsolete fuzzy rules that no longer describe the recently observed data trends are pruned. This enables eFSM to maintain a current and compact set of Mamdani-type if-then fuzzy rules that collectively generalizes and describes the salient associative mappings between the inputs and outputs of the underlying process being modeled. The learning and modeling performances of the proposed eFSM are evaluated using several benchmark applications and the results are encouraging.
Conceptual Coherence, Comprehension, and Vocabulary Acquisition: A Knowledge Effect?
ERIC Educational Resources Information Center
Cervetti, Gina N.; Wright, Tanya S.; Hwang, HyeJin
2016-01-01
Previous research has documented the role of readers' existing topic knowledge in supporting students' comprehension of text; yet, we know less about how to build students' knowledge in order to support comprehension and vocabulary learning. In the current study, we test the hypothesis that knowledge can be built and leveraged simultaneously in…
On the Performance Characteristics of Latent-Factor and Knowledge Tracing Models
ERIC Educational Resources Information Center
Klingler, Severin; Käser, Tanja; Solenthaler, Barbara; Gross, Markus
2015-01-01
Modeling student knowledge is a fundamental task of an intelligent tutoring system. A popular approach for modeling the acquisition of knowledge is Bayesian Knowledge Tracing (BKT). Various extensions to the original BKT model have been proposed, among them two novel models that unify BKT and Item Response Theory (IRT). Latent Factor Knowledge…
Experimental Evidence of the Knowledge Gap: Message Arousal, Motivation, and Time Delay
ERIC Educational Resources Information Center
Grabe, Maria Elizabeth; Yegiyan, Narine; Kamhawi, Rasha
2008-01-01
This study experimentally tested the knowledge gap from an information processing perspective. Specifically, knowledge acquisition was investigated under conditions of medium and low news message arousal, with time delay. Results show the persistence of a knowledge gap, particularly for low arousing messages. In fact, at low levels of message…
How has problem based learning fared in Pakistan?
Mahmud, Waqas; Hyder, Omar
2012-10-01
To conduct a systematic review of primary research in undergraduate medical education in Pakistan in order to evaluate PBL programs, examine outcomes and competencies influenced by PBL, and compare them with conventional learning (lecture based learning, LBL). Qualitative content analysis. Rawalpindi Medical College, Rawalpindi, from June 2010 - February 2011. Literature was searched using online resources. Studies evaluating outcomes influenced by PBL, or comparing PBL with lecture based learning (LBL) were selected. Due to heterogeneity, a qualitative content analysis was performed in which studies were classified according to the methods of assessment; results were then summarized by outcome and frequencies were calculated. Eleven studies were included. Apart from knowledge acquisition, students gave high ratings to PBL in selected outcomes, alone, and in comparison with LBL. There was a disagreement among results of studies that evaluated knowledge acquisition alone. Based on student perceptions, PBL has many advantages. However, the results of this review are limited due to heterogeneity and methodological weakness of studies, specially the studies that compared exam scores to assess knowledge acquisition.
ERIC Educational Resources Information Center
Pipp-Siegel, Sandra; Foltz, Carol
1997-01-01
Two studies tested whether 12- and 24-month olds' self-knowledge differed from their knowledge of others (mother or inanimate object), or whether toddlers' knowledge of persons (self and mother) differed from knowledge of objects. Results showed that 12-month olds were more sensitive than older toddlers to perceptual features of objects. Data were…
Moehring, Anne; Schroeders, Ulrich; Wilhelm, Oliver
2018-01-01
Medical education research has focused almost entirely on the education of future physicians. In comparison, findings on other health-related occupations, such as medical assistants, are scarce. With the current study, we wanted to examine the knowledge-is-power hypothesis in a real life educational setting and add to the sparse literature on medical assistants. Acquisition of vocational knowledge in vocational education and training (VET) was examined for medical assistant students ( n = 448). Differences in domain-specific vocational knowledge were predicted by crystallized and fluid intelligence in the course of VET. A multiple matrix design with 3 year-specific booklets was used for the vocational knowledge tests of the medical assistants. The unique and joint contributions of the predictors were investigated with structural equation modeling. Crystallized intelligence emerged as the strongest predictor of vocational knowledge at every stage of VET, while fluid intelligence only showed weak effects. The present results support the knowledge-is-power hypothesis, even in a broad and more naturalistic setting. This emphasizes the relevance of general knowledge for occupations, such as medical assistants, which are more focused on learning hands-on skills than the acquisition of academic knowledge.
Moehring, Anne; Schroeders, Ulrich; Wilhelm, Oliver
2018-01-01
Medical education research has focused almost entirely on the education of future physicians. In comparison, findings on other health-related occupations, such as medical assistants, are scarce. With the current study, we wanted to examine the knowledge-is-power hypothesis in a real life educational setting and add to the sparse literature on medical assistants. Acquisition of vocational knowledge in vocational education and training (VET) was examined for medical assistant students (n = 448). Differences in domain-specific vocational knowledge were predicted by crystallized and fluid intelligence in the course of VET. A multiple matrix design with 3 year-specific booklets was used for the vocational knowledge tests of the medical assistants. The unique and joint contributions of the predictors were investigated with structural equation modeling. Crystallized intelligence emerged as the strongest predictor of vocational knowledge at every stage of VET, while fluid intelligence only showed weak effects. The present results support the knowledge-is-power hypothesis, even in a broad and more naturalistic setting. This emphasizes the relevance of general knowledge for occupations, such as medical assistants, which are more focused on learning hands-on skills than the acquisition of academic knowledge. PMID:29449819
Huang, Jeannie S; Chun, Stanford; Sandhu, Amanpreet; Terrones, Laura
2013-11-01
To assess the Health and Obesity: Prevention and Education (HOPE) Curriculum Project, a web-based clinician education program that promotes appropriate screening, prevention, and management of weight among youth by pediatric practitioners, based on the 2007 Expert Committee recommendations. The project currently provides Maintenance of Certification (MOC) Part 4 credit through the American Board of Pediatrics. Participants identified themselves to the HOPE MOC Part 4 program. Enrollees were required to complete all continuing medical education modules (10.5 hours). Knowledge acquisition and self-reported confidence levels related to screening, prevention, and management practices of pediatric obesity were measured using preknowledge and postknowledge questionnaires. Participants were also required to perform a quality improvement project and submit practice performance data from repeated medical chart reviews over time. Knowledge acquisition, self-efficacy, and practice performance data were analyzed using repeated-measures analyses. The 51 participants demonstrated significant improvements in knowledge acquisition and self-efficacy scores after viewing individual modules. In addition, participants demonstrated significant improvements in measured clinical compliance with recommended practices over time. Participation in the HOPE MOC Part 4 program appeared to improve knowledge acquisition, self-efficacy, and physician compliance with recommended practice recommendations for the screening, prevention, and management of pediatric obesity. Further data are required to determine whether such practice-based improvements translate into actual reduction in patient weight and/or reduction in health-related costs related to overweight and obesity in youth. Copyright © 2013 Mosby, Inc. All rights reserved.
Fast-Acquisition/Weak-Signal-Tracking GPS Receiver for HEO
NASA Technical Reports Server (NTRS)
Wintemitz, Luke; Boegner, Greg; Sirotzky, Steve
2004-01-01
A report discusses the technical background and design of the Navigator Global Positioning System (GPS) receiver -- . a radiation-hardened receiver intended for use aboard spacecraft. Navigator is capable of weak signal acquisition and tracking as well as much faster acquisition of strong or weak signals with no a priori knowledge or external aiding. Weak-signal acquisition and tracking enables GPS use in high Earth orbits (HEO), and fast acquisition allows for the receiver to remain without power until needed in any orbit. Signal acquisition and signal tracking are, respectively, the processes of finding and demodulating a signal. Acquisition is the more computationally difficult process. Previous GPS receivers employ the method of sequentially searching the two-dimensional signal parameter space (code phase and Doppler). Navigator exploits properties of the Fourier transform in a massively parallel search for the GPS signal. This method results in far faster acquisition times [in the lab, 12 GPS satellites have been acquired with no a priori knowledge in a Low-Earth-Orbit (LEO) scenario in less than one second]. Modeling has shown that Navigator will be capable of acquiring signals down to 25 dB-Hz, appropriate for HEO missions. Navigator is built using the radiation-hardened ColdFire microprocessor and housing the most computationally intense functions in dedicated field-programmable gate arrays. The high performance of the algorithm and of the receiver as a whole are made possible by optimizing computational efficiency and carefully weighing tradeoffs among the sampling rate, data format, and data-path bit width.
Mitchell, Andrew Edward Paul
2017-04-01
In this study, we investigated the effects of training on knowledge acquisition and core competencies in cognitive and behavioral therapy (CBT). Forty-three students attended 15 half-day, weekly sessions and were tested with the Cognitive Therapy Awareness Scale (CTAS) at weeks 1 and 15 in a before and after study. The students' case studies were assessed with competency items 7-12 on the Cognitive Rating Scale-Revised (CTS-R). Improvements in the CTAS were modest. Key competencies on the CTS-R subscales at week 15 were also observed. CBT knowledge acquisition might improve patients' outcomes through impact on competencies. © 2015 Wiley Periodicals, Inc.
Ji, Lingling; Peng, Huamao; Xue, Xiaotong
2017-01-01
This study examined age differences in daily life events related to different types of social goals based on the socioemotional selectivity theory (SST), and determined whether the positivity effect existed in the context of social goals in older adults’ daily lives. Over a course of 14 days, 49 older adults and 36 younger adults wrote about up to three life events daily and rated the valence of each event. The findings indicated that (1) although both older and younger adults recorded events related to both emotional and knowledge-acquisition goals, the odds ratio for reporting a higher number of events related to emotional goals compared to the number of events related to knowledge-acquisition goals was 2.12 times higher in older adults than that observed in younger adults. (2) Considering the number of events, there was an age-related positivity effect only for knowledge-related goals, and (3) older adults’ ratings for events related to emotional and knowledge-acquisition goals were significantly more positive compared to those observed in younger adults. These findings supported the SST, and to some extent, the positivity effect was demonstrated in the context of social goals. PMID:28979227
Ji, Lingling; Peng, Huamao; Xue, Xiaotong
2017-01-01
This study examined age differences in daily life events related to different types of social goals based on the socioemotional selectivity theory (SST), and determined whether the positivity effect existed in the context of social goals in older adults' daily lives. Over a course of 14 days, 49 older adults and 36 younger adults wrote about up to three life events daily and rated the valence of each event. The findings indicated that (1) although both older and younger adults recorded events related to both emotional and knowledge-acquisition goals, the odds ratio for reporting a higher number of events related to emotional goals compared to the number of events related to knowledge-acquisition goals was 2.12 times higher in older adults than that observed in younger adults. (2) Considering the number of events, there was an age-related positivity effect only for knowledge-related goals, and (3) older adults' ratings for events related to emotional and knowledge-acquisition goals were significantly more positive compared to those observed in younger adults. These findings supported the SST, and to some extent, the positivity effect was demonstrated in the context of social goals.
Brasil, L M; de Azevedo, F M; Barreto, J M
2001-09-01
This paper proposes a hybrid expert system (HES) to minimise some complexity problems pervasive to the artificial intelligence such as: the knowledge elicitation process, known as the bottleneck of expert systems; the model choice for knowledge representation to code human reasoning; the number of neurons in the hidden layer and the topology used in the connectionist approach; the difficulty to obtain the explanation on how the network arrived to a conclusion. Two algorithms applied to developing of HES are also suggested. One of them is used to train the fuzzy neural network and the other to obtain explanations on how the fuzzy neural network attained a conclusion. To overcome these difficulties the cognitive computing was integrated to the developed system. A case study is presented (e.g. epileptic crisis) with the problem definition and simulations. Results are also discussed.
To have and to hold: personnel shortage in a Finnish healthcare organisation.
Heilmann, Pia
2010-07-01
Retirements of baby boomers will create a talent shortage in Finnish health care. Concurrently, difficulties exist in recruiting new personnel. This paper provides an overview concerning the bottlenecks in talent management in a Finnish hospital, and finds solutions for recruitment and retention problems of healthcare professionals (nurses and physicians). Because the healthcare staffing shortage is worldwide, the results of this paper are also useful internationally. The research was a qualitative case study and the research method used was group interview. Background data was gathered from the public media and healthcare trade organisations. The bottlenecks of talent management in hospital organisation seem to relate to retaining actions of senior personnel. Concurrently, the organisation should develop new practices for attracting new personnel. Very few efforts on image marketing and recruitment have been done. The Internet has not been fully exploited and recruitment information has not been sent even to the neighbouring nursing college. Job rotation has not been used as a help in recruitment and competence development. Difficulties exist in transmitting tacit knowledge from a retiring nurse to a junior nurse. Leadership skills of the superior seem to be important when retaining and committing senior personnel. Recruitment and retention problems encourage organisations to develop new recruitment and commitment practices as well as management and leadership skills.
Modeling cooperative driving behavior in freeway merges.
DOT National Transportation Integrated Search
2011-11-01
Merging locations are major sources of freeway bottlenecks and are therefore important for freeway operations analysis. Microscopic simulation tools have been successfully used to analyze merging bottlenecks and to design optimum geometric configurat...
Cloud Technology May Widen Genomic Bottleneck - TCGA
Computational biologist Dr. Ilya Shmulevich suggests that renting cloud computing power might widen the bottleneck for analyzing genomic data. Learn more about his experience with the Cloud in this TCGA in Action Case Study.
Potential performance bottleneck in Linux TCP
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wu, Wenji; Crawford, Matt; /Fermilab
2006-12-01
TCP is the most widely used transport protocol on the Internet today. Over the years, especially recently, due to requirements of high bandwidth transmission, various approaches have been proposed to improve TCP performance. The Linux 2.6 kernel is now preemptible. It can be interrupted mid-task, making the system more responsive and interactive. However, we have noticed that Linux kernel preemption can interact badly with the performance of the networking subsystem. In this paper we investigate the performance bottleneck in Linux TCP. We systematically describe the trip of a TCP packet from its ingress into a Linux network end system tomore » its final delivery to the application; we study the performance bottleneck in Linux TCP through mathematical modeling and practical experiments; finally we propose and test one possible solution to resolve this performance bottleneck in Linux TCP.« less
NASA Astrophysics Data System (ADS)
Huang, Y. Q.; Buyanova, I. A.; Yang, X. J.; Murayama, A.; Chen, W. M.
2018-04-01
We provide direct experimental evidence for the effect of a phonon bottleneck on exciton and spin generation in self-assembled In0.5Ga0.5As quantum dots (QDs). With the aid of tunable laser spectroscopy, we resolve and identify efficient exciton generation channels in the QDs mediated by longitudinal-optical (LO) phonons from an otherwise inhomogeneously broadened QD emission background that suffers from the phonon bottleneck effect in exciton generation. Spin-generation efficiency is found to be enhanced under the LO-assisted excitation condition due to suppressed spin relaxation accompanying accelerated exciton generation. These findings underline the importance of fine-tuning QD energy levels that will benefit potential spin-optoelectronic applications of QDs by reducing spin loss due to the phonon bottleneck.
NASA Astrophysics Data System (ADS)
Mishra, Bhavya; Chowdhury, Debashish
2017-06-01
We develop a two-species exclusion process with a distinct pair of entry and exit sites for each species of rigid rods. The relatively slower forward stepping of the rods in an extended bottleneck region, located in between the two entry sites, controls the extent of interference of the codirectional flow of the two species of rods. The relative positions of the sites of entry of the two species of rods with respect to the location of the bottleneck are motivated by a biological phenomenon. However, the primary focus of the study here is to explore the effects of the interference of the flow of the two species of rods on their spatiotemporal organization and the regulations of this interference by the extended bottleneck. By a combination of mean-field theory and computer simulation, we calculate the flux of both species of rods and their density profiles as well as the composite phase diagrams of the system. If the bottleneck is sufficiently stringent, then some of the phases become practically unrealizable, although not ruled out on the basis of any fundamental physical principle. Moreover, the extent of suppression of flow of the downstream entrants by the flow of the upstream entrants can also be regulated by the strength of the bottleneck. We speculate on the possible implications of the results in the context of the biological phenomenon that motivated the formulation of the theoretical model.
The Brazilian Science Data Center (BSDC)
NASA Astrophysics Data System (ADS)
de Almeida, Ulisses Barres; Bodmann, Benno; Giommi, Paolo; Brandt, Carlos H.
Astrophysics and Space Science are becoming increasingly characterised by what is now known as “big data”, the bottlenecks for progress partly shifting from data acquisition to “data mining”. Truth is that the amount and rate of data accumulation in many fields already surpasses the local capabilities for its processing and exploitation, and the efficient conversion of scientific data into knowledge is everywhere a challenge. The result is that, to a large extent, isolated data archives risk being progressively likened to “data graveyards”, where the information stored is not reused for scientific work. Responsible and efficient use of these large data-sets means democratising access and extracting the most science possible from it, which in turn signifies improving data accessibility and integration. Improving data processing capabilities is another important issue specific to researchers and computer scientists of each field. The project presented here wishes to exploit the enormous potential opened up by information technology at our age to advance a model for a science data center in astronomy which aims to expand data accessibility and integration to the largest possible extent and with the greatest efficiency for scientific and educational use. Greater access to data means more people producing and benefiting from information, whereas larger integration of related data from different origins means a greater research potential and increased scientific impact. The project of the BSDC is preoccupied, primarily, with providing tools and solutions for the Brazilian astronomical community. It nevertheless capitalizes on extensive international experience, and is developed in full cooperation with the ASI Science Data Center (ASDC), from the Italian Space Agency, granting it an essential ingredient of internationalisation. The BSDC is Virtual Observatory-complient and part of the “Open Universe”, a global initiative built under the auspices of the United Nations.
ERIC Educational Resources Information Center
Montrul, Silvina; Perpinan, Silvia
2011-01-01
The acquisition of the aspectual difference between the preterit and imperfect in the past tense and the acquisition of the contrast between subjunctive and indicative mood are classic problem areas in second language (L2) acquisition of Spanish by English-speaking learners (Collentine, 1995, 1998, 2003; Salaberry, 1999; Slabakova & Montrul, 2002;…
Coagulant Recovery from Water Treatment Residuals: A Review of Applicable Technologies
Keeley, J.; Jarvis, P.; Judd, S. J.
2014-01-01
Conventional water treatment consumes large quantities of coagulant and produces even greater volumes of sludge. Coagulant recovery (CR) presents an opportunity to reduce both the sludge quantities and the costs they incur, by regenerating and purifying coagulant before reuse. Recovery and purification must satisfy stringent potable regulations for harmful contaminants, while remaining competitive with commercial coagulants. These challenges have restricted uptake and lead research towards lower-gain, lower-risk alternatives. This review documents the context in which CR must be considered, before comparing the relative efficacies and bottlenecks of potential technologies, expediting identification of the major knowledge gaps and future research requirements. PMID:26064036
Identity, Knowledge and Participation: Health Theatre for Children
ERIC Educational Resources Information Center
Grabowski, Dan
2013-01-01
Purpose: The main aim of the paper is to explore whether health theatre as a school-based health promotion initiative communicates relevant health knowledge to children and the interrelated processes of identity development, knowledge acquisition and participation. Development of the definition of "health identity" was a subsidiary…
ERIC Educational Resources Information Center
Hartin, Travis L.; Stevenson, Colleen M.; Merriman, William E.
2016-01-01
The ability to judge the limits of one's own knowledge may play an important role in knowledge acquisition. The current study tested the prediction that preschoolers would judge the limits of their lexical knowledge more accurately if they were first exposed to a few objects of contrasting familiarity. Such preexposure was hypothesized to increase…
ERIC Educational Resources Information Center
Dahiyat, Samer E.; Al-Zu'bi, Zu'bi M. F.
2012-01-01
Knowledge management has often been linked to product development, innovation, and customisation. In particular, effective exploitation of customer knowledge, through engaging customers in a process of co-creation of products, exemplifies such a link. Accordingly, this research aims to identify those dimensions of knowledge management activities…
ERIC Educational Resources Information Center
Happ, Roland; Förster, Manuel; Zlatkin-Troitschanskaia, Olga; Carstensen, Vivian
2016-01-01
Study-related prior knowledge plays a decisive role in business and economics degree courses. Prior knowledge has a significant influence on knowledge acquisition in higher education, and teachers need information on it to plan their introductory courses accordingly. Very few studies have been conducted of first-year students' prior economic…
The Visual Representation and Acquisition of Driving Knowledge for Autonomous Vehicle
NASA Astrophysics Data System (ADS)
Zhang, Zhaoxia; Jiang, Qing; Li, Ping; Song, LiangTu; Wang, Rujing; Yu, Biao; Mei, Tao
2017-09-01
In this paper, the driving knowledge base of autonomous vehicle is designed. Based on the driving knowledge modeling system, the driving knowledge of autonomous vehicle is visually acquired, managed, stored, and maintenanced, which has vital significance for creating the development platform of intelligent decision-making systems of automatic driving expert systems for autonomous vehicle.
1992-05-01
methodology, knowledge acquisition, 140 requirements definition, information systems, information engineering, 16. PRICE CODE systems engineering...and knowledge resources. Like manpower, materials, and machines, information and knowledge assets are recognized as vital resources that can be...evolve towards an information -integrated enterprise. These technologies are designed to leverage information and knowledge resources as the key
KAM (Knowledge Acquisition Module): A tool to simplify the knowledge acquisition process
NASA Technical Reports Server (NTRS)
Gettig, Gary A.
1988-01-01
Analysts, knowledge engineers and information specialists are faced with increasing volumes of time-sensitive data in text form, either as free text or highly structured text records. Rapid access to the relevant data in these sources is essential. However, due to the volume and organization of the contents, and limitations of human memory and association, frequently: (1) important information is not located in time; (2) reams of irrelevant data are searched; and (3) interesting or critical associations are missed due to physical or temporal gaps involved in working with large files. The Knowledge Acquisition Module (KAM) is a microcomputer-based expert system designed to assist knowledge engineers, analysts, and other specialists in extracting useful knowledge from large volumes of digitized text and text-based files. KAM formulates non-explicit, ambiguous, or vague relations, rules, and facts into a manageable and consistent formal code. A library of system rules or heuristics is maintained to control the extraction of rules, relations, assertions, and other patterns from the text. These heuristics can be added, deleted or customized by the user. The user can further control the extraction process with optional topic specifications. This allows the user to cluster extracts based on specific topics. Because KAM formalizes diverse knowledge, it can be used by a variety of expert systems and automated reasoning applications. KAM can also perform important roles in computer-assisted training and skill development. Current research efforts include the applicability of neural networks to aid in the extraction process and the conversion of these extracts into standard formats.
Techniques for capturing expert knowledge - An expert systems/hypertext approach
NASA Technical Reports Server (NTRS)
Lafferty, Larry; Taylor, Greg; Schumann, Robin; Evans, Randy; Koller, Albert M., Jr.
1990-01-01
The knowledge-acquisition strategy developed for the Explosive Hazards Classification (EHC) Expert System is described in which expert systems and hypertext are combined, and broad applications are proposed. The EHC expert system is based on rapid prototyping in which primary knowledge acquisition from experts is not emphasized; the explosive hazards technical bulletin, technical guidance, and minimal interviewing are used to develop the knowledge-based system. Hypertext is used to capture the technical information with respect to four issues including procedural, materials, test, and classification issues. The hypertext display allows the integration of multiple knowlege representations such as clarifications or opinions, and thereby allows the performance of a broad range of tasks on a single machine. Among other recommendations, it is suggested that the integration of hypertext and expert systems makes the resulting synergistic system highly efficient.
NASA Technical Reports Server (NTRS)
Seamster, Thomas L.; Eike, David R.; Ames, Troy J.
1990-01-01
This presentation concentrates on knowledge acquisition and its application to the development of an expert module and a user interface for an Intelligent Tutoring System (ITS). The Systems Test and Operations Language (STOL) ITS is being developed to assist NASA control center personnel in learning a command and control language as it is used in mission operations rooms. The objective of the tutor is to impart knowledge and skills that will permit the trainee to solve command and control problems in the same way that the STOL expert solves those problems. The STOL ITS will achieve this object by representing the solution space in such a way that the trainee can visualize the intermediate steps, and by having the expert module production rules parallel the STOL expert's knowledge structures.
NASA Technical Reports Server (NTRS)
Stewart, Helen; Spence, Matt Chew; Holm, Jeanne; Koga, Dennis (Technical Monitor)
2001-01-01
This white paper explores how to increase the success and operation of critical, complex, national systems by effectively capturing knowledge management requirements within the federal acquisition process. Although we focus on aerospace flight systems, the principles outlined within may have a general applicability to other critical federal systems as well. Fundamental design deficiencies in federal, mission-critical systems have contributed to recent, highly visible system failures, such as the V-22 Osprey and the Delta rocket family. These failures indicate that the current mechanisms for knowledge management and risk management are inadequate to meet the challenges imposed by the rising complexity of critical systems. Failures of aerospace system operations and vehicles may have been prevented or lessened through utilization of better knowledge management and information management techniques.
Yoder, Paul J.; Woynaroski, Tiffany
2014-01-01
Seven empirical studies from this special issue and an overview chapter are reviewed to illustrate several points about studying the possible effects of treatment intensity manipulations on generalized skill or knowledge acquisition in students with disabilities. First, we make a case in favor of studying intensity as separate from complexity and expense of treatment. Second, we encourage researchers to define dependent variables in a way that allows us to determine whether treatment intensity effects on child skills and knowledge are highly generalized versus potentially context bound. Third, we acknowledge that effects of treatment intensity on generalized knowledge and skills likely vary according to student characteristics. Finally, we discuss important research design and measurement issues that are relevant to isolating the likely conditional effects of treatment intensity on generalized outcomes. PMID:25914513
Strapazzon, Giacomo; Migliaccio, Daniel; Fontana, Diego; Stawinoga, Agnieszka Elzbieta; Milani, Mario; Brugger, Hermann
2018-03-01
To explore baseline knowledge about avalanche guidelines and the Avalanche Victim Resuscitation Checklist (AVReCh) in Italy and the knowledge acquisition from a standardized lecture. Standardized lecture material discussing AVReCh was presented during 8 mountain medicine courses from November 2014 to April 2016 in different regions of Italy. To determine the knowledge acquisition from the lecture, a pre- and postlecture survey was utilized. A total of 193 surveys were analyzed. More than 50% of the participants had never participated in lectures/courses on avalanche guidelines, and less than 50% of the participants knew about the AVReCh before the lecture. The correct temporal sequence of reportable information in the basic life support section of the AVReCh was selected by 40% of the participants before the lecture and by 75% after the lecture (P<0.001). Within subgroups analysis, most groups saw significant improvement in performance (P<0.05). The selection of the correct burial time increased from 36 to 84% (P<0.05). Health care providers and mountain rescue personnel are not widely aware of avalanche guidelines. The standardized lecture significantly improved knowledge of the principles of avalanche management related to core AVReCh elements. However, the effect that this knowledge acquisition has on avalanche victim survival or adherence to the AVReCh in the field is yet to be determined. Copyright © 2017 Wilderness Medical Society. Published by Elsevier Inc. All rights reserved.
Rawson, Helen A; Liamputtong, Pranee
2010-08-01
This paper explores how a group of Vietnamese Australian young women acquire knowledge of sexual issues, and the impact the traditional Vietnamese culture has on the acquisition of this knowledge. It is based on a qualitative study that examined the factors which shape the sexual behaviour of Vietnamese Australian young women living in Australia. A Grounded Theory methodology was employed in this investigation, and involved in-depth interviews with 15 Vietnamese Australian young women aged 18-25 years, who reside in Victoria, Australia. The findings illustrated three key elements involved in the acquisition of knowledge of sexual issues: 'Accepting parental silence', 'Exploring sources of knowledge' and 'Needing culturally targeted information'. The young women desired discussion about sexual issues but accepted that cultural 'barriers' were formidable. Their desire conflicted with the traditional familial norm of 'silence' regarding sexual matters. Consequently, knowledge was sought outside the home, specifically from peers and the media. The importance of culturally appropriate and adequate sexual discussions for Vietnamese Australian young people was stressed, so that informed decisions could be made about their sexual lives. It is imperative for young people to have adequate and appropriate sexual education so that informed and safe sexual choices can be made. For young people from diverse cultural backgrounds, this education must be culturally appropriate and accessible, taking into consideration cultural mores regarding gender and sexual matters, as well as current beliefs in the 'mainstream' youth culture.
Vocabulary Levels and Size of Malaysian Undergraduates
ERIC Educational Resources Information Center
Harji, Madhubala Bava; Balakrishnan, Kavitha; Bhar, Sareen Kaur; Letchumanan, Krishnaveni
2015-01-01
Vocabulary is a fundamental requirement of language acquisition, and its competence enables independent reading and effective language acquisition. Effective language use requires adequate level of vocabulary knowledge; therefore, efforts must be made to identify students' vocabulary base for greater efficiency and competency in the language.…
NASA Technical Reports Server (NTRS)
Wilhite, Larry D.; Lee, S. C.; Lollar, Louis F.
1989-01-01
The design and implementation of the real-time data acquisition and processing system employed in the AMPERES project is described, including effective data structures for efficient storage and flexible manipulation of the data by the knowledge-based system (KBS), the interprocess communication mechanism required between the data acquisition system and the KBS, and the appropriate data acquisition protocols for collecting data from the sensors. Sensor data are categorized as critical or noncritical data on the basis of the inherent frequencies of the signals and the diagnostic requirements reflected in their values. The critical data set contains 30 analog values and 42 digital values and is collected every 10 ms. The noncritical data set contains 240 analog values and is collected every second. The collected critical and noncritical data are stored in separate circular buffers. Buffers are created in shared memory to enable other processes, i.e., the fault monitoring and diagnosis process and the user interface process, to freely access the data sets.
Increasingly automated procedure acquisition in dynamic systems
NASA Technical Reports Server (NTRS)
Mathe, Nathalie; Kedar, Smadar
1992-01-01
Procedures are widely used by operators for controlling complex dynamic systems. Currently, most development of such procedures is done manually, consuming a large amount of paper, time, and manpower in the process. While automated knowledge acquisition is an active field of research, not much attention has been paid to the problem of computer-assisted acquisition and refinement of complex procedures for dynamic systems. The Procedure Acquisition for Reactive Control Assistant (PARC), which is designed to assist users in more systematically and automatically encoding and refining complex procedures. PARC is able to elicit knowledge interactively from the user during operation of the dynamic system. We categorize procedure refinement into two stages: diagnosis - diagnose the failure and choose a repair - and repair - plan and perform the repair. The basic approach taken in PARC is to assist the user in all steps of this process by providing increased levels of assistance with layered tools. We illustrate the operation of PARC in refining procedures for the control of a robot arm.
Unveiling CO2 heterogeneous freezing plumes during champagne cork popping.
Liger-Belair, Gérard; Cordier, Daniel; Honvault, Jacques; Cilindre, Clara
2017-09-14
Cork popping from clear transparent bottles of champagne stored at different temperatures (namely, 6, 12, and 20 °C) was filmed through high-speed video imaging in the visible light spectrum. During the cork popping process, a plume mainly composed of gaseous CO 2 with traces of water vapour freely expands out of the bottleneck through ambient air. Most interestingly, for the bottles stored at 20 °C, the characteristic grey-white cloud of fog classically observed above the bottlenecks of champagne stored at lower temperatures simply disappeared. It is replaced by a more evanescent plume, surprisingly blue, starting from the bottleneck. We suggest that heterogeneous freezing of CO 2 occurs on ice water clusters homogeneously nucleated in the bottlenecks, depending on the saturation ratio experienced by gas-phase CO 2 after adiabatic expansion (indeed highly bottle temperature dependent). Moreover, and as observed for the bottles stored at 20 °C, we show that the freezing of only a small portion of all the available CO 2 is able to pump the energy released through adiabatic expansion, thus completely inhibiting the condensation of water vapour found in air packages adjacent to the gas volume gushing out of the bottleneck.
About the Role of the Bottleneck/Cork Interface on Oxygen Transfer.
Lagorce-Tachon, Aurélie; Karbowiak, Thomas; Paulin, Christian; Simon, Jean-Marc; Gougeon, Régis D; Bellat, Jean-Pierre
2016-09-07
The transfer of oxygen through a corked bottleneck was investigated using a manometric technique. First, the effect of cork compression on oxygen transfer was evaluated without considering the glass/cork interface. No significant effect of cork compression (at 23% strain, corresponding to the compression level of cork in a bottleneck for still wines) was noticeable on the effective diffusion coefficient of oxygen. The mean value of the effective diffusion coefficient is equal to 10(-8) m(2) s(-1), with a statistical distribution ranging from 10(-10) to 10(-7) m(2) s(-1), which is of the same order of magnitude as for the non-compressed cork. Then, oxygen transfer through cork compressed in a glass bottleneck was determined to assess the effect of the glass/cork interface. In the particular case of a gradient-imposed diffusion of oxygen through our model corked bottleneck system (dry cork without surface treatment; 200 and ∼0 hPa of oxygen on both sides of the sample), the mean effective diffusion coefficient is of 5 × 10(-7) m(2) s(-1), thus revealing the possible importance of the role of the glass/stopper interface in the oxygen transfer.
Liu, Li; Liu, Yue-Ping; Wang, Jing; An, Li-Wei; Jiao, Jian-Mei
2016-06-01
To investigate the effects of a knowledge-attitude-behaviour health education model on acquisition of disease-related knowledge and self-management behaviour by patients undergoing maintenance haemodialysis. Patients recently prescribed MHD were randomly assigned to a control group or an intervention group. Control group patients were treated with usual care and general education models. A specialist knowledge-attitude-behaviour health education model was applied to patients in the intervention group. Eighty-six patients were included (n = 43 per group). Before intervention, there were no significant between-group differences in disease knowledge and self-management behaviour. After 6 months' intervention, a significant between-group difference in acquisition of disease knowledge was observed. Self-management behaviour scores (control of body mass, reasonable diet, correct drug intake, physical activity, correct fistula care, disease condition monitoring, psychological and social behaviours) for the intervention group were also higher than those for the control group. These preliminary findings suggest that the knowledge-attitude-behaviour model appears to be a valuable tool for the health education of MHD patients. © The Author(s) 2016.
Liu, Li; Wang, Jing; An, Li-Wei; Jiao, Jian-Mei
2016-01-01
Objective To investigate the effects of a knowledge-attitude-behaviour health education model on acquisition of disease-related knowledge and self-management behaviour by patients undergoing maintenance haemodialysis. Methods Patients recently prescribed MHD were randomly assigned to a control group or an intervention group. Control group patients were treated with usual care and general education models. A specialist knowledge-attitude-behaviour health education model was applied to patients in the intervention group. Results Eighty-six patients were included (n = 43 per group). Before intervention, there were no significant between-group differences in disease knowledge and self-management behaviour. After 6 months’ intervention, a significant between-group difference in acquisition of disease knowledge was observed. Self-management behaviour scores (control of body mass, reasonable diet, correct drug intake, physical activity, correct fistula care, disease condition monitoring, psychological and social behaviours) for the intervention group were also higher than those for the control group. Conclusion These preliminary findings suggest that the knowledge-attitude-behaviour model appears to be a valuable tool for the health education of MHD patients. PMID:26951842
ERIC Educational Resources Information Center
Kong, Eric; Chadee, Doren; Raman, Revti
2012-01-01
This paper focuses on the processes by which firms, particularly knowledge intensive firms, can augment their overall knowledge stock by tapping into external sources of knowledge. It is argued that Top Management Teams' (TMTs') social intelligence is a critical learning capability in acquiring external knowledge that leads to strategic change.…
Hopkins, Allison L; Stepp, John Richard; McCarty, Christopher; Gordon, Judith S
2015-04-30
Ethnobotanical knowledge continues to be important for treating illness in many rural communities, despite access to health care clinics and pharmaceuticals. However, access to health care clinics and other modern services can have an impact on the distribution of medical ethnobotanical knowledge. Many factors have been shown to be associated with distributions in this type of knowledge. The goal of the sub-analyses reported in this paper was to better understand the relationship between herbal remedy knowledge, and two such factors, age and social network position, among the Yucatec Maya in Tabi, Yucatan. The sample consisted of 116 Yucatec Maya adults. Cultural consensus analysis was used to measure variation in herbal remedy knowledge using competence scores, which is a measure of participant agreement within a domain. Social network analysis was used to measure individual position within a network using in-degree scores, based on the number of people who asked an individual about herbal remedies. Surveys were used to capture relevant personal attributes, including age. Analysis revealed a significant positive correlation between age and the herbal medicine competence score for individuals 45 and under, and no relationship for individuals over 45. There was an insignificant relationship between in-degree and competence scores for individuals 50 and under and a significant positive correlation for those over 50. There are two possible mechanisms that could account for the differences between cohorts: 1) knowledge accumulation over time; and/or 2) the stunting of knowledge acquisition through delayed acquisition, competing treatment options, and changes in values. Primary ethnographic evidence suggests that both mechanisms may be at play in Tabi. Future studies using longitudinal or cross-site comparisons are necessary to determine the whether and how the second mechanism is influencing the different cohorts.
A flight expert system for on-board fault monitoring and diagnosis
NASA Technical Reports Server (NTRS)
Ali, Moonis
1990-01-01
An architecture for a flight expert system (FLES) to assist pilots in monitoring, diagnosing, and recovering from inflight faults is described. A prototype was implemented and an attempt was made to automate the knowledge acquisition process by employing a learning by being told methodology. The scope of acquired knowledge ranges from domain knowledge, including the information about objects and their relationships, to the procedural knowledge associated with the functionality of the mechanisms. AKAS (automatic knowledge acquisition system) is the constructed prototype for demonstration proof of concept, in which the expert directly interfaces with the knowledge acquisition system to ultimately construct the knowledge base for the particular application. The expert talks directly to the system using a natural language restricted only by the extent of the definitions in an analyzer dictionary, i.e., the interface understands a subset of concepts related to a given domain. In this case, the domain is the electrical system of the Boeing 737. Efforts were made to define and employ heuristics as well as algorithmic rules to conceptualize data produced by normal and faulty jet engine behavior examples. These rules were employed in developing the machine learning system (MLS). The input to MLS is examples which contain data of normal and faulty engine behavior and which are obtained from an engine simulation program. MLS first transforms the data into discrete selectors. Partial descriptions formed by those selectors are then generalized or specialized to generate concept descriptions about faults. The concepts are represented in the form of characteristic and discriminant descriptions, which are stored in the knowledge base and are employed to diagnose faults. MLS was successfully tested on jet engine examples.
Intermodal freight capacity box : intermodal freight bottleneck measures
DOT National Transportation Integrated Search
2000-09-01
The Bureau of Transportation Statistics in partnership with the U.S. Department of Transportation's Office of Intermodalism and the Federal Highway Administration sponsored the development of an Intermodal Bottleneck Evaluation Tool (IBET) to provide...
Advances and bottlenecks in microbial hydrogen production.
Stephen, Alan J; Archer, Sophie A; Orozco, Rafael L; Macaskie, Lynne E
2017-09-01
Biological production of hydrogen is poised to become a significant player in the future energy mix. This review highlights recent advances and bottlenecks in various approaches to biohydrogen processes, often in concert with management of organic wastes or waste CO 2 . Some key bottlenecks are highlighted in terms of the overall energy balance of the process and highlighting the need for economic and environmental life cycle analyses with regard also to socio-economic and geographical issues. © 2017 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology.
The Effects of Educational Delivery Methods on Knowledge Retention
ERIC Educational Resources Information Center
Turner, Craig; Turner, Kyle Dean
2017-01-01
In today's dynamic learning environment, educational delivery methods have become increasingly diverse. Using a unique opportunity to assess three types of course delivery--face-to-face, interactive television (iTV), and purely online delivery--the authors look at both initial knowledge acquisition and the retention of this knowledge. The results…
Assessing Student Perception of Practice Evaluation Knowledge in Introductory Research Methods
ERIC Educational Resources Information Center
Baker, Lisa R.; Pollio, David E.; Hudson, Ashley
2011-01-01
The authors explored the use of the Practice Evaluation Knowledge Scale (PEKS) to assess student perception of acquisition and retention of practice evaluation knowledge from an undergraduate research methods class. The authors sampled 2 semesters of undergraduate social work students enrolled in an introductory research methods course.…
Developing Librarians as Teachers: A Study of Their Pedagogical Knowledge
ERIC Educational Resources Information Center
Bewick, Laura; Corrall, Sheila
2010-01-01
The widespread involvement of librarians in information literacy education has raised concerns about their development as teachers, but there is little research on their acquisition and application of pedagogical knowledge. A questionnaire was used to collect mainly quantitative data about the teaching roles, pedagogical knowledge and professional…
Student Metacognitive Monitoring: Predicting Test Achievement from Judgment Accuracy
ERIC Educational Resources Information Center
Valdez, Alfred
2013-01-01
Metacognitive monitoring processes have been shown to be critical determinants of human learning. Metacognitive monitoring consist of various knowledge estimates that enable learners to engage in self-regulatory processes important for both the acquisition of knowledge and the monitoring of one's knowledge when engaged in assessment. This study…
Investigating Urban Eighth-Grade Students' Knowledge of Energy Resources
ERIC Educational Resources Information Center
Bodzin, Alec
2012-01-01
This study investigated urban eighth-grade students' knowledge of energy resources and associated issues including energy acquisition, energy generation, storage and transport, and energy consumption and conservation. A 39 multiple-choice-item energy resources knowledge assessment was completed by 1043 eighth-grade students in urban schools in two…
Identifying, anticipating, and mitigating freight bottlenecks on Alabama interstates.
DOT National Transportation Integrated Search
2011-07-31
"This project established a framework for the creation and maintenance of a statewide strategy for identifying, : anticipating, and mitigating freight bottlenecks on interstate highways in the state of Alabama. It used : methodology developed by Camb...
48 CFR 306.303-1 - Requirements.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Requirements. 306.303-1... ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 306.303-1 Requirements. (b... written in a manner to permit an individual without technical knowledge of the requirement to understand...
48 CFR 306.303-1 - Requirements.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Requirements. 306.303-1... ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 306.303-1 Requirements. (b... written in a manner to permit an individual without technical knowledge of the requirement to understand...
48 CFR 306.303-1 - Requirements.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Requirements. 306.303-1... ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 306.303-1 Requirements. (b... written in a manner to permit an individual without technical knowledge of the requirement to understand...
48 CFR 306.303-1 - Requirements.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Requirements. 306.303-1... ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 306.303-1 Requirements. (b... written in a manner to permit an individual without technical knowledge of the requirement to understand...
48 CFR 306.303-1 - Requirements.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Requirements. 306.303-1... ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 306.303-1 Requirements. (b... written in a manner to permit an individual without technical knowledge of the requirement to understand...
48 CFR 3415.505 - Content of unsolicited proposals.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Content of unsolicited proposals. 3415.505 Section 3415.505 Federal Acquisition Regulations System DEPARTMENT OF EDUCATION... the best of my knowledge and belief, that: a. This proposal has not been prepared under Government...
Bigrams and the Richness of the Stimulus
ERIC Educational Resources Information Center
Kam, Xuan-Nga Cao; Stoyneshka, Iglika; Tornyova, Lidiya; Fodor, Janet D.; Sakas, William G.
2008-01-01
Recent challenges to Chomsky's "poverty of the stimulus" thesis for language acquisition suggest that children's primary data may carry "indirect evidence" about linguistic constructions despite containing no instances of them. Indirect evidence is claimed to suffice for grammar acquisition, without need for innate knowledge. This article reports…
Genetic bottlenecks during systemic movement of Cucumber mosaic virus vary in different host plants
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ali, Akhtar; Roossinck, Marilyn J., E-mail: mroossinck@noble.or
2010-09-01
Genetic bottlenecks are stochastic events that narrow variation in a population. We compared bottlenecks during the systemic infection of Cucumber mosaic virus (CMV) in four host plants. We mechanically inoculated an artificial population of twelve CMV mutants to young leaves of tomato, pepper, Nicotiana benthamiana, and squash. The inoculated leaves and primary and secondary systemically infected leaves were sampled at 2, 10, and 15 days post-inoculation. All twelve mutants were detected in all of the inoculated leaves. The number of mutants recovered from the systemically infected leaves of all host species was reduced significantly, indicating bottlenecks in systemic movement. Themore » recovery frequencies of a few of the mutants were significantly different in each host probably due to host-specific selective forces. These results have implications for the differences in virus population variation that is seen in different host plants.« less
A recent bottleneck of Y chromosome diversity coincides with a global change in culture
Saag, Lauri; Vicente, Mário; Sayres, Melissa A. Wilson; Järve, Mari; Talas, Ulvi Gerst; Rootsi, Siiri; Ilumäe, Anne-Mai; Mägi, Reedik; Mitt, Mario; Pagani, Luca; Puurand, Tarmo; Faltyskova, Zuzana; Clemente, Florian; Cardona, Alexia; Metspalu, Ene; Sahakyan, Hovhannes; Yunusbayev, Bayazit; Hudjashov, Georgi; DeGiorgio, Michael; Loogväli, Eva-Liis; Eichstaedt, Christina; Eelmets, Mikk; Chaubey, Gyaneshwer; Tambets, Kristiina; Litvinov, Sergei; Mormina, Maru; Xue, Yali; Ayub, Qasim; Zoraqi, Grigor; Korneliussen, Thorfinn Sand; Akhatova, Farida; Lachance, Joseph; Tishkoff, Sarah; Momynaliev, Kuvat; Ricaut, François-Xavier; Kusuma, Pradiptajati; Razafindrazaka, Harilanto; Pierron, Denis; Cox, Murray P.; Sultana, Gazi Nurun Nahar; Willerslev, Rane; Muller, Craig; Westaway, Michael; Lambert, David; Skaro, Vedrana; Kovačevic´, Lejla; Turdikulova, Shahlo; Dalimova, Dilbar; Khusainova, Rita; Trofimova, Natalya; Akhmetova, Vita; Khidiyatova, Irina; Lichman, Daria V.; Isakova, Jainagul; Pocheshkhova, Elvira; Sabitov, Zhaxylyk; Barashkov, Nikolay A.; Nymadawa, Pagbajabyn; Mihailov, Evelin; Seng, Joseph Wee Tien; Evseeva, Irina; Migliano, Andrea Bamberg; Abdullah, Syafiq; Andriadze, George; Primorac, Dragan; Atramentova, Lubov; Utevska, Olga; Yepiskoposyan, Levon; Marjanovic´, Damir; Kushniarevich, Alena; Behar, Doron M.; Gilissen, Christian; Vissers, Lisenka; Veltman, Joris A.; Balanovska, Elena; Derenko, Miroslava; Malyarchuk, Boris; Metspalu, Andres; Fedorova, Sardana; Eriksson, Anders; Manica, Andrea; Mendez, Fernando L.; Karafet, Tatiana M.; Veeramah, Krishna R.; Bradman, Neil; Hammer, Michael F.; Osipova, Ludmila P.; Balanovsky, Oleg; Khusnutdinova, Elza K.; Johnsen, Knut; Remm, Maido; Thomas, Mark G.; Tyler-Smith, Chris; Underhill, Peter A.; Willerslev, Eske; Nielsen, Rasmus; Metspalu, Mait; Villems, Richard
2015-01-01
It is commonly thought that human genetic diversity in non-African populations was shaped primarily by an out-of-Africa dispersal 50–100 thousand yr ago (kya). Here, we present a study of 456 geographically diverse high-coverage Y chromosome sequences, including 299 newly reported samples. Applying ancient DNA calibration, we date the Y-chromosomal most recent common ancestor (MRCA) in Africa at 254 (95% CI 192–307) kya and detect a cluster of major non-African founder haplogroups in a narrow time interval at 47–52 kya, consistent with a rapid initial colonization model of Eurasia and Oceania after the out-of-Africa bottleneck. In contrast to demographic reconstructions based on mtDNA, we infer a second strong bottleneck in Y-chromosome lineages dating to the last 10 ky. We hypothesize that this bottleneck is caused by cultural changes affecting variance of reproductive success among males. PMID:25770088
Variable Cultural Acquisition Costs Constrain Cumulative Cultural Evolution
Mesoudi, Alex
2011-01-01
One of the hallmarks of the human species is our capacity for cumulative culture, in which beneficial knowledge and technology is accumulated over successive generations. Yet previous analyses of cumulative cultural change have failed to consider the possibility that as cultural complexity accumulates, it becomes increasingly costly for each new generation to acquire from the previous generation. In principle this may result in an upper limit on the cultural complexity that can be accumulated, at which point accumulated knowledge is so costly and time-consuming to acquire that further innovation is not possible. In this paper I first review existing empirical analyses of the history of science and technology that support the possibility that cultural acquisition costs may constrain cumulative cultural evolution. I then present macroscopic and individual-based models of cumulative cultural evolution that explore the consequences of this assumption of variable cultural acquisition costs, showing that making acquisition costs vary with cultural complexity causes the latter to reach an upper limit above which no further innovation can occur. These models further explore the consequences of different cultural transmission rules (directly biased, indirectly biased and unbiased transmission), population size, and cultural innovations that themselves reduce innovation or acquisition costs. PMID:21479170
2012-10-13
Business & Public Policy Naval Postgraduate School Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the collection...presented in this report was supported by the Acquisition Research Program of the Graduate School of Business & Public Policy at the Naval...Program GRADUATE SCHOOL OF BUSINESS & PUBLIC POLICY - iii - NAVAL POSTGRADUATE SCHOOL NPS-AM-12-206 ACQUISITION RESEARCH SPONSORED REPORT SERIES
Implicit Knowledge, Explicit Knowledge, and Achievement in Second Language (L2) Spanish
ERIC Educational Resources Information Center
Gutierrez, Xavier
2012-01-01
Implicit and explicit knowledge of the second language (L2) are two central constructs in the field of second language acquisition (SLA). In recent years, there has been a renewed interest in obtaining valid and reliable measures of L2 learners' implicit and explicit knowledge (e.g., Bowles, 2011; R. Ellis, 2005). The purpose of the present study…
ERIC Educational Resources Information Center
Liaw, En-Chong
2009-01-01
This study integrates the purposes of communication, i.e. in-class and on-line discussions, with problem solving skills in the process of learning professional knowledge of pre-service teachers. It attempts to foster both comprehension of professional knowledge and the attitude of contextualizing knowledge with situational factors. More…
Big Data and Knowledge Management: A Possible Course to Combine Them Together
ERIC Educational Resources Information Center
Hijazi, Sam
2017-01-01
Big data (BD) is the buzz phrase these days. Everyone is talking about its potential, its volume, its variety, and its velocity. Knowledge management (KM) has been around since the mid-1990s. The goals of KM have been to collect, store, categorize, mine, and process data into knowledge. The methods of knowledge acquisition varied from…
1995-09-01
vital processes of a business. process, IDEF, method, methodology, modeling, knowledge acquisition, requirements definition, information systems... knowledge resources. Like manpower, materials, and machines, information and knowledge assets are recognized as vital resources that can be leveraged to...integrated enterprise. These technologies are designed to leverage information and knowledge resources as the key enablers for high quality systems
Sketching for Knowledge Capture: A Progress Report
2002-01-16
understanding , qualitative modeling, knowledge acquisition, analogy, diagrammatic reasoning, spatial reasoning. INTRODUCTION Sketching is often used...main limits of sKEA’s expressivity are (a) the predicate vocabulary in its knowledge base and (b) how natural it is to express a piece of information ...Sketching for knowledge capture: A progress report Kenneth D. Forbus Qualitative Reasoning Group Northwestern University 1890 Maple Avenue
ERIC Educational Resources Information Center
Square, Nicole Decuir
2012-01-01
Nurses require ongoing opportunities to expand knowledge and skills; this expansion of knowledge and skills is one aspect of continued competence. One method that may be used to maintain and refine knowledge and skills is participation in continuing education activities. However, there has been little inquiry into creative strategies used in…
Genetic diversity in Malus ×domestica (Rosaceae) through time in response to domestication.
Gross, Briana L; Henk, Adam D; Richards, Christopher M; Fazio, Gennaro; Volk, Gayle M
2014-10-01
• Patterns of genetic diversity in domesticated plants are affected by geographic region of origin and cultivation, intentional artificial selection, and unintentional genetic bottlenecks. While bottlenecks are mainly associated with the initial domestication process, they can also affect diversity during crop improvement. Here, we investigate the impact of the improvement process on the genetic diversity of domesticated apple in comparison with other perennial and annual fruit crops.• Apple cultivars that were developed at various times (ranging from the 13th through the 20th century) and 11 of the 15 apple cultivars that are used for 90% of the apple production in the United States were surveyed for genetic diversity based on either 9 or 19 simple sequence repeats (SSRs). Diversity was compared using standard metrics and model-based approaches based on expected heterozygosity (He) at equilibrium. Improvement bottleneck data for fruit crops were also collected from the literature.• Domesticated apples showed no significant reduction in genetic diversity through time across the last eight centuries. Diversity was generally high, with an average He > 0.7 for apples from all centuries. However, diversity of the apples currently used for the bulk of commercial production was lower.• The improvement bottleneck in domesticated apples appears to be mild or nonexistent, in contrast to improvement bottlenecks in many annual and perennial fruit crops, as documented from the literature survey. The low diversity of the subset of cultivars used for commercial production, however, indicates that an improvement bottleneck may be in progress for this perennial crop. © 2014 Botanical Society of America, Inc.
NASA Astrophysics Data System (ADS)
Watanuki, Keiichi; Kojima, Kazuyuki
The environment in which Japanese industry has achieved great respect is changing tremendously due to the globalization of world economies, while Asian countries are undergoing economic and technical development as well as benefiting from the advances in information technology. For example, in the design of custom-made casting products, a designer who lacks knowledge of casting may not be able to produce a good design. In order to obtain a good design and manufacturing result, it is necessary to equip the designer and manufacturer with a support system related to casting design, or a so-called knowledge transfer and creation system. This paper proposes a new virtual reality based knowledge acquisition and job training system for casting design, which is composed of the explicit and tacit knowledge transfer systems using synchronized multimedia and the knowledge internalization system using portable virtual environment. In our proposed system, the education content is displayed in the immersive virtual environment, whereby a trainee may experience work in the virtual site operation. Provided that the trainee has gained explicit and tacit knowledge of casting through the multimedia-based knowledge transfer system, the immersive virtual environment catalyzes the internalization of knowledge and also enables the trainee to gain tacit knowledge before undergoing on-the-job training at a real-time operation site.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Fairman, J.F.
Franchise terms can shape the structure and direction for much of the electricity industry`s future. The electricity distribution franchise can become a wide-mouth jar quenching the large retail customers` thirst for low-cost, reliable energy - or a bottleneck for captive customers.
Unclogging America's arteries : prescriptions for healthier highways
DOT National Transportation Integrated Search
1999-11-01
This first-of-its-kind study examines a significant cause of traffic congestion - America's worst bottlenecks - from three perspectives. First, it examines how much worse the gridlock will become at each of the 18 worst bottlenecks in the United Stat...
Saving Time, Saving Money: The Economics of Unclogging America's Worst Bottlenecks
DOT National Transportation Integrated Search
2000-01-01
A 1999 study by the American Highway Users Alliance entitled "Unclogging America's Arteries: Prescriptions for Healthier Highways" identified the 166 worst bottlenecks in the country and evaluated the benefits of removing them. By assigning monetary ...
2015-01-01
Background Preterm birth is the leading cause of child death worldwide. Small and sick newborns require timely, high-quality inpatient care to survive. This includes provision of warmth, feeding support, safe oxygen therapy and effective phototherapy with prevention and treatment of infections. Inpatient care for newborns requires dedicated ward space, staffed by health workers with specialist training and skills. Many of the estimated 2.8 million newborns that die every year do not have access to such specialised care. Methods The bottleneck analysis tool was applied in 12 countries in Africa and Asia as part of the Every Newborn Action Plan process. Country workshops involved technical experts to complete the survey tool, which is designed to synthesise and grade health system "bottlenecks" (or factors that hinder the scale up) of maternal-newborn intervention packages. For this paper, we used quantitative and qualitative methods to analyse the bottleneck data, and combined these with literature review, to present priority bottlenecks and actions relevant to different health system building blocks for inpatient care of small and sick newborns. Results Inpatient care of small and sick newborns is an intervention package highlighted by all country workshop participants as having critical health system challenges. Health system building blocks with the highest graded (significant or major) bottlenecks were health workforce (10 out of 12 countries) and health financing (10 out of 12 countries), followed by community ownership and partnership (9 out of 12 countries). Priority actions based on solution themes for these bottlenecks are discussed. Conclusions Whilst major bottlenecks to the scale-up of quality inpatient newborn care are present, effective solutions exist. For all countries included, there is a critical need for a neonatal nursing cadre. Small and sick newborns require increased, sustained funding with specific insurance schemes to cover inpatient care and avoid catastrophic out-of-pocket payments. Core competencies, by level of care, should be defined for monitoring of newborn inpatient care, as with emergency obstetric care. Rather than fatalism that small and sick newborns will die, community interventions need to create demand for accessible, high-quality, family-centred inpatient care, including kangaroo mother care, so that every newborn can survive and thrive. PMID:26391335
2015-01-01
Background Preterm birth complications are the leading cause of deaths for children under five years. Antenatal corticosteroids (ACS) are effective at reducing mortality and serious morbidity amongst infants born at <34 weeks gestation. WHO guidelines strongly recommend use of ACS for women at risk of imminent preterm birth where gestational age, imminent preterm birth, and risk of maternal infection can be assessed, and appropriate maternal/newborn care provided. However, coverage remains low in high-burden countries for reasons not previously systematically investigated. Methods The bottleneck analysis tool was applied in 12 countries in Africa and Asia as part of the Every Newborn Action Plan process. Country workshops involved technical experts to complete the survey tool, which is designed to synthesise and grade health system "bottlenecks", factors that hinder the scale up, of maternal-newborn intervention packages. We used quantitative and qualitative methods to analyse the bottleneck data, combined with literature review, to present priority bottlenecks and actions relevant to different health system building blocks for ACS. Results Eleven out of twelve countries provided data in response to the ACS questionnaire. Health system building blocks most frequently reported as having significant or very major bottlenecks were health information systems (11 countries), essential medical products and technologies (9 out of 11 countries) and health service delivery (9 out of 11 countries). Bottlenecks included absence of coverage data, poor gestational age metrics, lack of national essential medicines listing, discrepancies between prescribing authority and provider cadres managing care, delays due to referral, and lack of supervision, mentoring and quality improvement systems. Conclusions Analysis centred on health system building blocks in which 9 or more countries (>75%) reported very major or significant bottlenecks. Health information systems should include improved gestational age assessment and track ACS coverage, use and outcomes. Better health service delivery requires clarified policy assigning roles by level of care and cadre of provider, dependent on capability to assess gestational age and risk of preterm birth, and the implementation of guidelines with adequate supervision, mentoring and quality improvement systems, including audit and feedback. National essential medicines lists should include dexamethasone for antenatal use, and dexamethasone should be integrated into supply logistics. PMID:26390927
Facilitation and Practice in Verb Acquisition
ERIC Educational Resources Information Center
Keren-Portnoy, Tamar
2006-01-01
This paper presents a model of syntax acquisition, whose main points are as follows: Syntax is acquired in an item-based manner; early learning facilitates subsequent learning--as evidenced by the accelerating rate of new verbs entering a given structure; and mastery of syntactic knowledge is typically achieved through practice--as evidenced by…
Toward More Substantial Theories of Language Acquisition
ERIC Educational Resources Information Center
Jenson, Cinnamon Ann
2015-01-01
Cognitive linguists argue that certain sets of knowledge of language are innate. However, critics have argued that the theoretical concept of "innateness" should be eliminated since it is ambiguous and insubstantial. In response, I aim to strengthen theories of language acquisition and identify ways to make them more substantial. I…
2012-12-27
of Work UCC Uniform Commercial Code USD(AT&L) Under Secretary of Defense for Acquisition, Technology, and Logistics WBS Work Breakdown Structure...intensive career field. The FAR, the DFARS, and other federal agency supplements of the FAR, the Uniform Commercial Code ( UCC ), installation guidelines
Developmental Perspectives on the Acquisition of the Passive
ERIC Educational Resources Information Center
Crawford, Jean Lenore
2012-01-01
This dissertation investigates the acquisition of the passive. The apparent cross-linguistic delay of the verbal passive compared to other constructions suggests children's knowledge is somehow restricted, leading some to propose the difficulty arises because of syntactic maturation (Wexler 2004, Orfitelli 2012) or because of a heavy reliance…
IRTs of the ABCs: Children's Letter Name Acquisition
ERIC Educational Resources Information Center
Phillips, Beth M.; Piasta, Shayne B.; Anthony, Jason L.; Lonigan, Christopher J.; Francis, David J.
2012-01-01
We examined the developmental sequence of letter name knowledge acquisition by children from 2 to five years of age. Data from 2 samples representing diverse regions, ethnicity, and socioeconomic backgrounds (ns=1074 and 500) were analyzed using item response theory (IRT) and differential item functioning techniques. Results from factor analyses…
Statistical Learning Is Related to Early Literacy-Related Skills
ERIC Educational Resources Information Center
Spencer, Mercedes; Kaschak, Michael P.; Jones, John L.; Lonigan, Christopher J.
2015-01-01
It has been demonstrated that statistical learning, or the ability to use statistical information to learn the structure of one's environment, plays a role in young children's acquisition of linguistic knowledge. Although most research on statistical learning has focused on language acquisition processes, such as the segmentation of words from…
Statistical Literacy among Applied Linguists and Second Language Acquisition Researchers
ERIC Educational Resources Information Center
Loewen, Shawn; Lavolette, Elizabeth; Spino, Le Anne; Papi, Mostafa; Schmidtke, Jens; Sterling, Scott; Wolff, Dominik
2014-01-01
The importance of statistical knowledge in applied linguistics and second language acquisition (SLA) research has been emphasized in recent publications. However, the last investigation of the statistical literacy of applied linguists occurred more than 25 years ago (Lazaraton, Riggenbach, & Ediger, 1987). The current study undertook a partial…
Using Vocabulary Notebooks for Vocabulary Acquisition and Teaching
ERIC Educational Resources Information Center
Dubiner, Deborah
2017-01-01
Vocabulary knowledge is recognized as an essential element for second language acquisition and reading comprehension. One known way to encourage and support vocabulary development amongst second language learners is keeping a vocabulary notebook. The primary purpose of the present study was to document two aspects of student teachers' own…
Concept Mapping Assessment of Media Assisted Learning in Interdisciplinary Science Education
NASA Astrophysics Data System (ADS)
Schaal, Steffen; Bogner, Franz X.; Girwidz, Raimund
2010-05-01
Acquisition of conceptual knowledge is a central aim in science education. In this study we monitored an interdisciplinary hypermedia assisted learning unit on hibernation and thermodynamics based on cooperative learning. We used concept mapping for the assessment, applying a pre-test/post-test design. In our study, 106 9th graders cooperated by working in pairs ( n = 53) for six lessons. As an interdisciplinary learning activity in such complex knowledge domains has to combine many different aspects, we focused on long-term knowledge. Learners working cooperatively in dyads constructed computer-supported concept maps which were analysed by specific software. The data analysis encompassed structural aspects of the knowledge corresponding to a target reference map. After the learning unit, the results showed the acquisition of higher-order domain-specific knowledge structures which indicates successful interdisciplinary learning through the hypermedia learning environment. The benefit of using a computer-assisted concept mapping assessment for research in science education, and in science classrooms is considered.
Knowledge acquisition, semantic text mining, and security risks in health and biomedical informatics
Huang, Jingshan; Dou, Dejing; Dang, Jiangbo; Pardue, J Harold; Qin, Xiao; Huan, Jun; Gerthoffer, William T; Tan, Ming
2012-01-01
Computational techniques have been adopted in medical and biological systems for a long time. There is no doubt that the development and application of computational methods will render great help in better understanding biomedical and biological functions. Large amounts of datasets have been produced by biomedical and biological experiments and simulations. In order for researchers to gain knowledge from original data, nontrivial transformation is necessary, which is regarded as a critical link in the chain of knowledge acquisition, sharing, and reuse. Challenges that have been encountered include: how to efficiently and effectively represent human knowledge in formal computing models, how to take advantage of semantic text mining techniques rather than traditional syntactic text mining, and how to handle security issues during the knowledge sharing and reuse. This paper summarizes the state-of-the-art in these research directions. We aim to provide readers with an introduction of major computing themes to be applied to the medical and biological research. PMID:22371823
Effect of Cardiac Arrhythmia Simulation on Nursing Students' Knowledge Acquisition and Retention.
Tubaishat, Ahmad; Tawalbeh, Loai I
2015-09-01
The realistic and practical environment that simulation provides is an extremely useful part of the teaching process. Simulation is widely used in health and nursing education today. This study aims to evaluate the effect of simulation-based teaching on the acquisition and retention of arrhythmia-related knowledge among nursing students. A randomized controlled design involving a pretest-posttest was used. Nursing students were allocated randomly either to the experimental group (n = 47), who attended simulation scenarios on cardiac arrhythmia, or to the control group (n = 44) who received a traditional lecture on the same topic. A paired t test showed that the mean knowledge score at the posttest was significantly higher than at the pretest for both groups. However, participants in the experimental group demonstrated significantly increased knowledge of cardiac arrhythmia in the first and the second posttest compared with those in the control group. Thus, simulation is superior and significantly improves students' arrhythmia knowledge. © The Author(s) 2014.
The knowledge-value chain: A conceptual framework for knowledge translation in health.
Landry, Réjean; Amara, Nabil; Pablos-Mendes, Ariel; Shademani, Ramesh; Gold, Irving
2006-08-01
This article briefly discusses knowledge translation and lists the problems associated with it. Then it uses knowledge-management literature to develop and propose a knowledge-value chain framework in order to provide an integrated conceptual model of knowledge management and application in public health organizations. The knowledge-value chain is a non-linear concept and is based on the management of five dyadic capabilities: mapping and acquisition, creation and destruction, integration and sharing/transfer, replication and protection, and performance and innovation.
The knowledge-value chain: A conceptual framework for knowledge translation in health.
Landry, Réjean; Amara, Nabil; Pablos-Mendes, Ariel; Shademani, Ramesh; Gold, Irving
2006-01-01
This article briefly discusses knowledge translation and lists the problems associated with it. Then it uses knowledge-management literature to develop and propose a knowledge-value chain framework in order to provide an integrated conceptual model of knowledge management and application in public health organizations. The knowledge-value chain is a non-linear concept and is based on the management of five dyadic capabilities: mapping and acquisition, creation and destruction, integration and sharing/transfer, replication and protection, and performance and innovation. PMID:16917645
Duan, Yuhua; Chen, Liao; Zhou, Haidong; Zhou, Xi; Zhang, Chi; Zhang, Xinliang
2017-04-03
Real-time electrical spectrum analysis is of great significance for applications involving radio astronomy and electronic warfare, e.g. the dynamic spectrum monitoring of outer space signal, and the instantaneous capture of frequency from other electronic systems. However, conventional electrical spectrum analyzer (ESA) has limited operation speed and observation bandwidth due to the electronic bottleneck. Therefore, a variety of photonics-assisted methods have been extensively explored due to the bandwidth advantage of the optical domain. Alternatively, we proposed and experimentally demonstrated an ultrafast ESA based on all-optical Fourier transform and temporal magnification in this paper. The radio-frequency (RF) signal under test is temporally multiplexed to the spectrum of an ultrashort pulse, thus the frequency information is converted to the time axis. Moreover, since the bandwidth of this ultrashort pulse is far beyond that of the state-of-the-art photo-detector, a temporal magnification system is applied to stretch the time axis, and capture the RF spectrum with 1-GHz resolution. The observation bandwidth of this ultrafast ESA is over 20 GHz, limited by that of the electro-optic modulator. Since all the signal processing is in the optical domain, the acquisition frame rate can be as high as 50 MHz. This ultrafast ESA scheme can be further improved with better dispersive engineering, and is promising for some ultrafast spectral information acquisition applications.
Parallel asynchronous systems and image processing algorithms
NASA Technical Reports Server (NTRS)
Coon, D. D.; Perera, A. G. U.
1989-01-01
A new hardware approach to implementation of image processing algorithms is described. The approach is based on silicon devices which would permit an independent analog processing channel to be dedicated to evey pixel. A laminar architecture consisting of a stack of planar arrays of the device would form a two-dimensional array processor with a 2-D array of inputs located directly behind a focal plane detector array. A 2-D image data stream would propagate in neuronlike asynchronous pulse coded form through the laminar processor. Such systems would integrate image acquisition and image processing. Acquisition and processing would be performed concurrently as in natural vision systems. The research is aimed at implementation of algorithms, such as the intensity dependent summation algorithm and pyramid processing structures, which are motivated by the operation of natural vision systems. Implementation of natural vision algorithms would benefit from the use of neuronlike information coding and the laminar, 2-D parallel, vision system type architecture. Besides providing a neural network framework for implementation of natural vision algorithms, a 2-D parallel approach could eliminate the serial bottleneck of conventional processing systems. Conversion to serial format would occur only after raw intensity data has been substantially processed. An interesting challenge arises from the fact that the mathematical formulation of natural vision algorithms does not specify the means of implementation, so that hardware implementation poses intriguing questions involving vision science.
Tomesko, Jennifer; Touger-Decker, Riva; Dreker, Margaret; Zelig, Rena; Parrott, James Scott
2017-01-01
To explore knowledge and skill acquisition outcomes related to learning physical examination (PE) through computer-assisted instruction (CAI) compared with a face-to-face (F2F) approach. A systematic literature review and meta-analysis published between January 2001 and December 2016 was conducted. Databases searched included Medline, Cochrane, CINAHL, ERIC, Ebsco, Scopus, and Web of Science. Studies were synthesized by study design, intervention, and outcomes. Statistical analyses included DerSimonian-Laird random-effects model. In total, 7 studies were included in the review, and 5 in the meta-analysis. There were no statistically significant differences for knowledge (mean difference [MD] = 5.39, 95% confidence interval [CI]: -2.05 to 12.84) or skill acquisition (MD = 0.35, 95% CI: -5.30 to 6.01). The evidence does not suggest a strong consistent preference for either CAI or F2F instruction to teach students/trainees PE. Further research is needed to identify conditions which examine knowledge and skill acquisition outcomes that favor one mode of instruction over the other.
Gagnon, Marie-Pierre; Gagnon, Johanne; Desmartis, Marie; Njoya, Merlin
2013-01-01
This study aimed to assess the effectiveness of a blended-teaching intervention using Internet-based tutorials coupled with traditional lectures in an introduction to research undergraduate nursing course. Effects of the intervention were compared with conventional, face-to-face classroom teaching on three outcomes: knowledge, satisfaction, and self-learning readiness. A two-group, randomized, controlled design was used, involving 112 participants. Descriptive statistics and analysis of covariance (ANCOVA) were performed. The teaching method was found to have no direct impact on knowledge acquisition, satisfaction, and self-learning readiness. However, motivation and teaching method had an interaction effect on knowledge acquisition by students. Among less motivated students, those in the intervention group performed better than those who received traditional training. These findings suggest that this blended-teaching method could better suit some students, depending on their degree of motivation and level of self-directed learning readiness.
Acquisition of Fire Safety Knowledge and Skills With Virtual Reality Simulation.
Rossler, Kelly L; Sankaranarayanan, Ganesh; Duvall, Adrianne
2018-05-25
Prelicensure nursing students seeking to enter perioperative nursing need preparatory fire safety knowledge and skills training to participate as a member of an operating room (OR) team. This pilot study examined the effectiveness of the Virtual Electrosurgery Skill Trainer (VEST) on OR fire safety skills among prelicensure nursing students. An experimental pretest-posttest design was used in this study. Twenty nursing students were randomized to a control or an intervention group. Knowledge and skills acquisition of OR fire safety were assessed. There were no statistically significant findings in knowledge for either group. Fisher exact test demonstrated significant relationships between the skills performance criteria of following emergency procedures for a fire and demonstrating PASS (pull-aim-squeeze-sweep) technique (P = .001). Academic and hospital educators may consider incorporating virtual reality simulation to teach fire safety education or reinforce general fire safety practices to nursing students and novice nurses.
Knowledge-Based Hierarchies: Using Organizations to Understand the Economy
ERIC Educational Resources Information Center
Garicano, Luis; Rossi-Hansberg, Esteban
2015-01-01
Incorporating the decision of how to organize the acquisition, use, and communication of knowledge into economic models is essential to understand a wide variety of economic phenomena. We survey the literature that has used knowledge-based hierarchies to study issues such as the evolution of wage inequality, the growth and productivity of firms,…
ERIC Educational Resources Information Center
Jing, Tang; Dancheng, Luo; Ye, Zhao
2016-01-01
Purpose: The entrepreneurship is a course of gaining knowledge from the failure and stimulating positive energy constantly. The entrepreneur's psychological resilience is the key to gain knowledge (positive energy) from failure (negative energy). The education of undergraduate entrepreneurship is one of the priorities these days. Educators shall…
Development of Orthographic Knowledge in German-Speaking Children: A 2-Year Longitudinal Study
ERIC Educational Resources Information Center
Ise, Elena; Arnoldi, Carolin Judith; Schulte-Körne, Gerd
2014-01-01
There is growing evidence that children develop orthographic knowledge from the very beginning of literacy acquisition. This study investigated the development of German-speaking children's orthographic knowledge with a nonword choice task. One nonword in each pair contained a frequent consonant doublet ("zommul") and the other…
Preservice and Inservice Teachers' Knowledge of Language Constructs in Finland
ERIC Educational Resources Information Center
Aro, Mikko; Björn, Piia Maria
2016-01-01
The aim of the study was to explore the Finnish preservice and inservice teachers' knowledge of language constructs relevant for literacy acquisition. A total of 150 preservice teachers and 74 inservice teachers participated in the study by filling out a questionnaire that assessed self-perceived expertise in reading instruction, knowledge of…
Preparation for College General Chemistry: More than Just a Matter of Content Knowledge Acquisition
ERIC Educational Resources Information Center
Cracolice, Mark S.; Busby, Brittany D.
2015-01-01
This study investigates the potential of five factors that may be predictive of success in college general chemistry courses: prior knowledge of common alternate conceptions, intelligence, scientific reasoning ability, proportional reasoning ability, and attitude toward chemistry. We found that both prior knowledge and scientific reasoning ability…
Coming Full Circle: Indigenous Knowledge, Environment, and Our Future
ERIC Educational Resources Information Center
McGregor, Deborah
2004-01-01
Traditional Ecological Knowledge (TEK) as a construct of broader society is a relatively recent phenomenon, and the field that supports the acquisition of environmental knowledge from Aboriginal people has rapidly grown over the last two decades. In part, TEK has emerged from the growing recognition that Indigenous people all over the world…
ERIC Educational Resources Information Center
Nezhnov, Peter; Kardanova, Elena; Vasilyeva, Marina; Ludlow, Larry
2015-01-01
The present study tested the possibility of operationalizing levels of knowledge acquisition based on Vygotsky's theory of cognitive growth. An assessment tool (SAM-Math) was developed to capture a hypothesized hierarchical structure of mathematical knowledge consisting of procedural, conceptual, and functional levels. In Study 1, SAM-Math was…
The Effectiveness of Knowledge Networks: An Investigation of Manufacturing SMEs
ERIC Educational Resources Information Center
Hughes, Tim; O'Regan, Nicholas; Sims, Martin A.
2009-01-01
Purpose: Although considerable attention in the extant literature has been devoted to knowledge acquisition and transfer within firms, there is a dearth of research on the effectiveness of outside sources of knowledge for technology-based small to medium-sized enterprises (SMEs). Furthermore, the majority of empirical studies in this area focus on…
A Construct Validation of the Mental Models Learning Outcome Using Exploratory Factor Analysis.
ERIC Educational Resources Information Center
Sheehan, Joseph; Tessmer, Martin
A mental model is a knowledge structure composed of concepts and the relations between them. Mental models are distinct from declarative and procedural knowledge--they go beyond semantic relationships and skills acquisition and contain varied intellectual skills and knowledge. This study describes an initial investigation into the construct…
Knowledge to Manage the Knowledge Society
ERIC Educational Resources Information Center
Minati, Gianfranco
2012-01-01
Purpose: The purpose of this research is to make evident the inadequateness of concepts and language based on industrial knowledge still used in current practices by managers to cope with problems of the post-industrial societies characterised by non-linear process of emergence and acquisition of properties. The purpose is to allow management to…
Lexical Access and Dual-Task Performance: Determining the Locus of the Bottleneck
NASA Technical Reports Server (NTRS)
Allen, Phil
2004-01-01
During the two years of funding for NASA Grant "NCC21325, Lexical access and dual-task performance: Determining the locus of the bottleneck," we completed three experiments involving the psychological refractory period (PRP) and word frequency.
Two retrievals from a single cue: A bottleneck persists across episodic and semantic memory.
Orscheschek, Franziska; Strobach, Tilo; Schubert, Torsten; Rickard, Timothy
2018-05-01
There is evidence in the literature that two retrievals from long-term memory cannot occur in parallel. To date, however, that work has explored only the case of two retrievals from newly acquired episodic memory. These studies demonstrated a retrieval bottleneck even after dual-retrieval practice. That retrieval bottleneck may be a global property of long-term memory retrieval, or it may apply only to the case of two retrievals from episodic memory. In the current experiments, we explored whether that apparent dual-retrieval bottleneck applies to the case of one retrieval from episodic memory and one retrieval from highly overlearned semantic memory. Across three experiments, subjects learned to retrieve a left or right keypress response form a set of 14 unique word cues (e.g., black-right keypress). In addition, they learned a verbal response which involved retrieving the antonym of the presented cue (e.g., black-"white"). In the dual-retrieval condition, subjects had to retrieve both the keypress response and the antonym word. The results suggest that the retrieval bottleneck is superordinate to specific long-term memory systems and holds across different memory components. In addition, the results support the assumption of a cue-level response chunking account of learned retrieval parallelism.
Mutational Effects and Population Dynamics During Viral Adaptation Challenge Current Models
Miller, Craig R.; Joyce, Paul; Wichman, Holly A.
2011-01-01
Adaptation in haploid organisms has been extensively modeled but little tested. Using a microvirid bacteriophage (ID11), we conducted serial passage adaptations at two bottleneck sizes (104 and 106), followed by fitness assays and whole-genome sequencing of 631 individual isolates. Extensive genetic variation was observed including 22 beneficial, several nearly neutral, and several deleterious mutations. In the three large bottleneck lines, up to eight different haplotypes were observed in samples of 23 genomes from the final time point. The small bottleneck lines were less diverse. The small bottleneck lines appeared to operate near the transition between isolated selective sweeps and conditions of complex dynamics (e.g., clonal interference). The large bottleneck lines exhibited extensive interference and less stochasticity, with multiple beneficial mutations establishing on a variety of backgrounds. Several leapfrog events occurred. The distribution of first-step adaptive mutations differed significantly from the distribution of second-steps, and a surprisingly large number of second-step beneficial mutations were observed on a highly fit first-step background. Furthermore, few first-step mutations appeared as second-steps and second-steps had substantially smaller selection coefficients. Collectively, the results indicate that the fitness landscape falls between the extremes of smooth and fully uncorrelated, violating the assumptions of many current mutational landscape models. PMID:21041559
Rubin, Daniel L; Hewett, Micheal; Oliver, Diane E; Klein, Teri E; Altman, Russ B
2002-01-01
Ontologies are useful for organizing large numbers of concepts having complex relationships, such as the breadth of genetic and clinical knowledge in pharmacogenomics. But because ontologies change and knowledge evolves, it is time consuming to maintain stable mappings to external data sources that are in relational format. We propose a method for interfacing ontology models with data acquisition from external relational data sources. This method uses a declarative interface between the ontology and the data source, and this interface is modeled in the ontology and implemented using XML schema. Data is imported from the relational source into the ontology using XML, and data integrity is checked by validating the XML submission with an XML schema. We have implemented this approach in PharmGKB (http://www.pharmgkb.org/), a pharmacogenetics knowledge base. Our goals were to (1) import genetic sequence data, collected in relational format, into the pharmacogenetics ontology, and (2) automate the process of updating the links between the ontology and data acquisition when the ontology changes. We tested our approach by linking PharmGKB with data acquisition from a relational model of genetic sequence information. The ontology subsequently evolved, and we were able to rapidly update our interface with the external data and continue acquiring the data. Similar approaches may be helpful for integrating other heterogeneous information sources in order make the diversity of pharmacogenetics data amenable to computational analysis.
Vernaglia, Lawrence W; Herman, Dimitry S; Ziegler, Rachel Schneller
2005-01-01
Lawyers and clients contemplating a health care transaction must have a strong working knowledge not only of the applicable law, but also of the provider's needs and culture. As illustrated by a recent Delaware court decision, Interim Healthcare, Inc. et al. v. Spherion Corporation, parties engaging in health care provider acquisitions are well advised to select a team of experienced business and legal advisors with specialized knowledge in health care practices that can find and address any suspicious activities before it is too late.
An initial assessment of freight bottlenecks on highways.
DOT National Transportation Integrated Search
2005-10-01
This white paper is an initial effort to identify and quantify, on a national basis, highway bottlenecks that delay trucks and increase costs to businesses and consumers. The paper is the first to look specifically at the impacts and costs of highway...
Knowledge-acquisition tools for medical knowledge-based systems.
Lanzola, G; Quaglini, S; Stefanelli, M
1995-03-01
Knowledge-based systems (KBS) have been proposed to solve a large variety of medical problems. A strategic issue for KBS development and maintenance are the efforts required for both knowledge engineers and domain experts. The proposed solution is building efficient knowledge acquisition (KA) tools. This paper presents a set of KA tools we are developing within a European Project called GAMES II. They have been designed after the formulation of an epistemological model of medical reasoning. The main goal is that of developing a computational framework which allows knowledge engineers and domain experts to interact cooperatively in developing a medical KBS. To this aim, a set of reusable software components is highly recommended. Their design was facilitated by the development of a methodology for KBS construction. It views this process as comprising two activities: the tailoring of the epistemological model to the specific medical task to be executed and the subsequent translation of this model into a computational architecture so that the connections between computational structures and their knowledge level counterparts are maintained. The KA tools we developed are illustrated taking examples from the behavior of a KBS we are building for the management of children with acute myeloid leukemia.
Staphylococcus aureus infection dynamics.
Pollitt, Eric J G; Szkuta, Piotr T; Burns, Nicola; Foster, Simon J
2018-06-01
Staphylococcus aureus is a human commensal that can also cause systemic infections. This transition requires evasion of the immune response and the ability to exploit different niches within the host. However, the disease mechanisms and the dominant immune mediators against infection are poorly understood. Previously it has been shown that the infecting S. aureus population goes through a population bottleneck, from which very few bacteria escape to establish the abscesses that are characteristic of many infections. Here we examine the host factors underlying the population bottleneck and subsequent clonal expansion in S. aureus infection models, to identify underpinning principles of infection. The bottleneck is a common feature between models and is independent of S. aureus strain. Interestingly, the high doses of S. aureus required for the widely used "survival" model results in a reduced population bottleneck, suggesting that host defences have been simply overloaded. This brings into question the applicability of the survival model. Depletion of immune mediators revealed key breakpoints and the dynamics of systemic infection. Loss of macrophages, including the liver Kupffer cells, led to increased sensitivity to infection as expected but also loss of the population bottleneck and the spread to other organs still occurred. Conversely, neutrophil depletion led to greater susceptibility to disease but with a concomitant maintenance of the bottleneck and lack of systemic spread. We also used a novel microscopy approach to examine abscess architecture and distribution within organs. From these observations we developed a conceptual model for S. aureus disease from initial infection to mature abscess. This work highlights the need to understand the complexities of the infectious process to be able to assign functions for host and bacterial components, and why S. aureus disease requires a seemingly high infectious dose and how interventions such as a vaccine may be more rationally developed.
Kerner, Boris S
2015-12-01
We have revealed a growing local speed wave of increase in speed that can randomly occur in synchronized flow (S) at a highway bottleneck. The development of such a traffic flow instability leads to free flow (F) at the bottleneck; therefore, we call this instability an S→F instability. Whereas the S→F instability leads to a local increase in speed (growing acceleration wave), in contrast, the classical traffic flow instability introduced in the 1950s-1960s and incorporated later in a huge number of traffic flow models leads to a growing wave of a local decrease in speed (growing deceleration wave). We have found that the S→F instability can occur only if there is a finite time delay in driver overacceleration. The initial speed disturbance of increase in speed (called "speed peak") that initiates the S→F instability occurs usually at the downstream front of synchronized flow at the bottleneck. There can be many speed peaks with random amplitudes that occur randomly over time. It has been found that the S→F instability exhibits a nucleation nature: Only when a speed peak amplitude is large enough can the S→F instability occur; in contrast, speed peaks of smaller amplitudes cause dissolving speed waves of a local increase in speed (dissolving acceleration waves) in synchronized flow. We have found that the S→F instability governs traffic breakdown-a phase transition from free flow to synchronized flow (F→S transition) at the bottleneck: The nucleation nature of the S→F instability explains the metastability of free flow with respect to an F→S transition at the bottleneck.
NASA Astrophysics Data System (ADS)
Kerner, Boris S.
2015-12-01
We have revealed a growing local speed wave of increase in speed that can randomly occur in synchronized flow (S) at a highway bottleneck. The development of such a traffic flow instability leads to free flow (F) at the bottleneck; therefore, we call this instability an S →F instability. Whereas the S →F instability leads to a local increase in speed (growing acceleration wave), in contrast, the classical traffic flow instability introduced in the 1950s-1960s and incorporated later in a huge number of traffic flow models leads to a growing wave of a local decrease in speed (growing deceleration wave). We have found that the S →F instability can occur only if there is a finite time delay in driver overacceleration. The initial speed disturbance of increase in speed (called "speed peak") that initiates the S →F instability occurs usually at the downstream front of synchronized flow at the bottleneck. There can be many speed peaks with random amplitudes that occur randomly over time. It has been found that the S →F instability exhibits a nucleation nature: Only when a speed peak amplitude is large enough can the S →F instability occur; in contrast, speed peaks of smaller amplitudes cause dissolving speed waves of a local increase in speed (dissolving acceleration waves) in synchronized flow. We have found that the S →F instability governs traffic breakdown—a phase transition from free flow to synchronized flow (F →S transition) at the bottleneck: The nucleation nature of the S →F instability explains the metastability of free flow with respect to an F →S transition at the bottleneck.
The acquisition and development of fitness trainers' professional knowledge.
De Lyon, Alexander T C; Cushion, Christopher J
2013-05-01
This study investigated the acquisition and development of fitness trainers' knowledge and how this is related to their practice as health and exercise professionals. Semi-structured interviews were conducted with 11 fitness trainers, who had successfully completed a course accredited by a Register of Exercise Professionals (REPs) certifying organization. Findings were organized using Coombs and Ahmed's conceptual framework of formal, nonformal, and informal learning and later analyzed using Sfard's metaphors of learning. Results suggested that fitness trainers learn in multiple and complex ways, many of which are informal and arise through the naturalistic processes that occur within the context of their everyday work. The study concludes that there is a need for greater integration between the current formal (REPs) accreditation system and informal knowledge developed while working as a fitness trainer.
Psycholinguistic Techniques and Resources in Second Language Acquisition Research
ERIC Educational Resources Information Center
Roberts, Leah
2012-01-01
In this article, a survey of current psycholinguistic techniques relevant to second language acquisition (SLA) research is presented. I summarize many of the available methods and discuss their use with particular reference to two critical questions in current SLA research: (1) What does a learner's current knowledge of the second language (L2)…
Reference Frames during the Acquisition and Development of Spatial Memories
ERIC Educational Resources Information Center
Kelly, Jonathan W.; McNamara, Timothy P.
2010-01-01
Four experiments investigated the role of reference frames during the acquisition and development of spatial knowledge, when learning occurs incrementally across views. In two experiments, participants learned overlapping spatial layouts. Layout 1 was first studied in isolation, and Layout 2 was later studied in the presence of Layout 1. The…
ERIC Educational Resources Information Center
Wilson, Christine
2017-01-01
Preservice teachers must have opportunities in their university teaching programs to apply theories of second language learning. Courses in second language acquisition and English as a second language methodology are essential to prepare mainstream teachers for teaching culturally and linguistically diverse learners. Additionally, creating a…
Development of Teaching Expertise Viewed through the Dreyfus Model of Skill Acquisition
ERIC Educational Resources Information Center
Lyon, Lucinda J.
2015-01-01
This study was designed to explore development of skill acquisition in dental education, utilizing the Dreyfus and Dreyfus continuum. By identifying what skill progression may be recognized in the expert dental educator and what experiences appear to influence this growth, the knowledge gained may inform more efficient, effective faculty support,…
Developing Teaching Expertise in Dental Education
ERIC Educational Resources Information Center
Lyon, Lucinda J.
2009-01-01
This exploratory study was designed to develop a baseline model of expertise in dental education utilizing the Dreyfus and Dreyfus continuum of skill acquisition. The goal was the development of a baseline model of expertise, which will contribute to the body of knowledge about dental faculty skill acquisition and may enable dental schools to…
ERIC Educational Resources Information Center
Luntley, Michael
2005-01-01
In this paper I propose a contrast between learning as the acquisition of theories and learning as the development of insight. I then suggest that, in a great many cases, the cognitive achievement by which we come to organise behaviour rationally is the development of insight, where this is independent of the acquisition of knowledge regimented in…
Skill Acquisition: Compilation of Weak-Method Problem Solutions.
ERIC Educational Resources Information Center
Anderson, John R.
According to the ACT theory of skill acquisition, cognitive skills are encoded by a set of productions, which are organized according to a hierarchical goal structure. People solve problems in new domains by applying weak problem-solving procedures to declarative knowledge they have about this domain. From these initial problem solutions,…
Early Acquisition of Gender Agreement in the Spanish Noun Phrase: Starting Small
ERIC Educational Resources Information Center
Mariscal, Sonia
2009-01-01
Nativist and constructivist accounts differ in their characterization of children's knowledge of grammatical categories. In this paper we present research on the process of acquisition of a particular grammatical system, gender agreement in the Spanish noun phrase, in children under three years of age. The design of the longitudinal study employed…
The Acquisition of Korean Plural Marking by Native English Speakers
ERIC Educational Resources Information Center
Hwang, Sun Hee
2013-01-01
This study investigated the L2 acquisition of Korean plural marking by English-speaking learners within a feature-reassembly approach--a formal feature-based approach suggesting that native-like attainment of L2 morphosyntactic knowledge is determined by whether learners can reconfigure the formal features assembled in functional categories and…
Variability, Negative Evidence, and the Acquisition of Verb Argument Constructions
ERIC Educational Resources Information Center
Perfors, Amy; Tenenbaum, Joshua B.; Wonnacott, Elizabeth
2010-01-01
We present a hierarchical Bayesian framework for modeling the acquisition of verb argument constructions. It embodies a domain-general approach to learning higher-level knowledge in the form of inductive constraints (or overhypotheses), and has been used to explain other aspects of language development such as the shape bias in learning object…
The Teaching-Learning Environment, an Information-Dynamic Approach
ERIC Educational Resources Information Center
De Blasio, Cataldo; Järvinen, Mika
2014-01-01
In the present study a generalized approach is given for the description of acquisition procedures with a particular focus on the knowledge acquisition process. The learning progression is given as an example here letting the theory to be applied to different situations. An analytical approach is performed starting from the generalized fundamental…
Logical Thinking Abilities among Form 4 Students in the Interior Division of Sabah, Malaysia
ERIC Educational Resources Information Center
Fah, Lay Yoon
2009-01-01
The science curriculum in Malaysia emphasizes the acquisition of scientific skills, thinking skills, and the inculcation of scientific attitudes and noble values. Besides that, the acquisition of scientific and technological knowledge and its application to the natural phenomena and students' daily experiences are also equally emphasized. The…
Lin, Chi-Hung; Krisp, Christoph; Packer, Nicolle H; Molloy, Mark P
2018-02-10
Glycoproteomics investigates glycan moieties in a site specific manner to reveal the functional roles of protein glycosylation. Identification of glycopeptides from data-dependent acquisition (DDA) relies on high quality MS/MS spectra of glycopeptide precursors and often requires manual validation to ensure confident assignments. In this study, we investigated pseudo-MRM (MRM-HR) and data-independent acquisition (DIA) as alternative acquisition strategies for glycopeptide analysis. These approaches allow data acquisition over the full MS/MS scan range allowing data re-analysis post-acquisition, without data re-acquisition. The advantage of MRM-HR over DDA for N-glycopeptide detection was demonstrated from targeted analysis of bovine fetuin where all three N-glycosylation sites were detected, which was not the case with DDA. To overcome the duty cycle limitation of MRM-HR acquisition needed for analysis of complex samples such as plasma we trialed DIA. This allowed development of a targeted DIA method to identify N-glycopeptides without pre-defined knowledge of the glycan composition, thus providing the potential to identify N-glycopeptides with unexpected structures. This workflow was demonstrated by detection of 59 N-glycosylation sites from 41 glycoproteins from a HILIC enriched human plasma tryptic digest. 21 glycoforms of IgG1 glycopeptides were identified including two truncated structures that are rarely reported. We developed a data-independent mass spectrometry workflow to identify specific glycopeptides from complex biological mixtures. The novelty is that this approach does not require glycan composition to be pre-defined, thereby allowing glycopeptides carrying unexpected glycans to be identified. This is demonstrated through the analysis of immunoglobulins in human plasma where we detected two IgG1 glycoforms that are rarely observed. Copyright © 2017 Elsevier B.V. All rights reserved.
Faurby, S; Werdelin, L; Svenning, J C
2016-05-05
Dobrynin et al. (Genome Biol 16:277, 2015) recently published the complete genome of the cheetah (Acinonyx jubatus) and provided an exhaustive set of analyses supporting the famously low genetic variation in the species, known for several decades. Their genetic analyses represent state-of-the-art and we do not criticize them. However, their interpretation of the results is inconsistent with current knowledge of cheetah evolution. Dobrynin et al. suggest that the causes of the two inferred bottlenecks at ∼ 100,000 and 10,000 years ago were immigration by cheetahs from North America and end-Pleistocene megafauna extinction, respectively, but the first explanation is impossible and the second implausible.
Operational Plan Ontology Model for Interconnection and Interoperability
NASA Astrophysics Data System (ADS)
Long, F.; Sun, Y. K.; Shi, H. Q.
2017-03-01
Aiming at the assistant decision-making system’s bottleneck of processing the operational plan data and information, this paper starts from the analysis of the problem of traditional expression and the technical advantage of ontology, and then it defines the elements of the operational plan ontology model and determines the basis of construction. Later, it builds up a semi-knowledge-level operational plan ontology model. Finally, it probes into the operational plan expression based on the operational plan ontology model and the usage of the application software. Thus, this paper has the theoretical significance and application value in the improvement of interconnection and interoperability of the operational plan among assistant decision-making systems.
2012-01-01
The increasing size and complexity of exome/genome sequencing data requires new tools for clinical geneticists to discover disease-causing variants. Bottlenecks in identifying the causative variation include poor cross-sample querying, constantly changing functional annotation and not considering existing knowledge concerning the phenotype. We describe a methodology that facilitates exploration of patient sequencing data towards identification of causal variants under different genetic hypotheses. Annotate-it facilitates handling, analysis and interpretation of high-throughput single nucleotide variant data. We demonstrate our strategy using three case studies. Annotate-it is freely available and test data are accessible to all users at http://www.annotate-it.org. PMID:23013645
Antibacterial Drug Discovery: Some Assembly Required.
Tommasi, Rubén; Iyer, Ramkumar; Miller, Alita A
2018-05-11
Our limited understanding of the molecular basis for compound entry into and efflux out of Gram-negative bacteria is now recognized as a key bottleneck for the rational discovery of novel antibacterial compounds. Traditional, large-scale biochemical or target-agnostic phenotypic antibacterial screening efforts have, as a result, not been very fruitful. A main driver of this knowledge gap has been the historical lack of predictive cellular assays, tools, and models that provide structure-activity relationships to inform optimization of compound accumulation. A variety of recent approaches has recently been described to address this conundrum. This Perspective explores these approaches and considers ways in which their integration could successfully redirect antibacterial drug discovery efforts.
Data Understanding Applied to Optimization
NASA Technical Reports Server (NTRS)
Buntine, Wray; Shilman, Michael
1998-01-01
The goal of this research is to explore and develop software for supporting visualization and data analysis of search and optimization. Optimization is an ever-present problem in science. The theory of NP-completeness implies that the problems can only be resolved by increasingly smarter problem specific knowledge, possibly for use in some general purpose algorithms. Visualization and data analysis offers an opportunity to accelerate our understanding of key computational bottlenecks in optimization and to automatically tune aspects of the computation for specific problems. We will prototype systems to demonstrate how data understanding can be successfully applied to problems characteristic of NASA's key science optimization tasks, such as central tasks for parallel processing, spacecraft scheduling, and data transmission from a remote satellite.
SAR image registration based on Susan algorithm
NASA Astrophysics Data System (ADS)
Wang, Chun-bo; Fu, Shao-hua; Wei, Zhong-yi
2011-10-01
Synthetic Aperture Radar (SAR) is an active remote sensing system which can be installed on aircraft, satellite and other carriers with the advantages of all day and night and all-weather ability. It is the important problem that how to deal with SAR and extract information reasonably and efficiently. Particularly SAR image geometric correction is the bottleneck to impede the application of SAR. In this paper we introduces image registration and the Susan algorithm knowledge firstly, then introduces the process of SAR image registration based on Susan algorithm and finally presents experimental results of SAR image registration. The Experiment shows that this method is effective and applicable, no matter from calculating the time or from the calculation accuracy.
Genetic diversity in Malus × domestica (Rosaceae) through time in response to domestication
USDA-ARS?s Scientific Manuscript database
Patterns of genetic diversity in domesticated plants are affected by geographic region of origin and cultivation, intentional artificial selection, and unintentional loss of diversity referred to as genetic bottlenecks. While bottlenecks are mainly associated with the initial domestication process, ...
Dynamic bottleneck elimination in mattress manufacturing line using theory of constraints.
Gundogar, Emin; Sari, Murat; Kokcam, Abdullah H
2016-01-01
There is a tough competition in the furniture sector like other sectors. Along with the varying product range, production system should also be renewed on a regular basis and the production costs should be kept under control. In this study, spring mattress manufacturing line of a furniture manufacturing company is analyzed. The company wants to increase its production output with new investments. The objective is to find the bottlenecks in production line in order to balance the semi-finished material flow. These bottlenecks are investigated and several different scenarios are tested to improve the current manufacturing system. The problem with a main theme based on the elimination of the bottleneck is solved using Goldratt and Cox's theory of constraints with a simulation based heuristic method. Near optimal alternatives are determined by system models built in Arena 13.5 simulation software. Results show that approximately 46 % capacity enhancements with 2 buffer stocks have increased average production by 88.8 %.
Weger-Lucarelli, James; Garcia, Selene M; Rückert, Claudia; Byas, Alex; O'Connor, Shelby L; Aliota, Matthew T; Friedrich, Thomas C; O'Connor, David H; Ebel, Gregory D
2018-06-20
Arboviruses such as Zika virus (ZIKV, Flaviviridae; Flavivirus) must replicate in both mammalian and insect hosts possessing strong immune defenses. Accordingly, transmission between and replication within hosts involves genetic bottlenecks, during which viral population size and genetic diversity may be significantly reduced. To help quantify these bottlenecks and their effects, we constructed 4 "barcoded" ZIKV populations that theoretically contain thousands of barcodes each. After identifying the most diverse barcoded virus, we passaged this virus 3 times in 2 mammalian and mosquito cell lines and characterized the population using deep sequencing of the barcoded region of the genome. C6/36 maintain higher barcode diversity, even after 3 passages, than Vero. Additionally, field-caught mosquitoes exposed to the virus to assess bottlenecks in a natural host. A progressive reduction in barcode diversity occurred throughout systemic infection of these mosquitoes. Differences in bottlenecks during systemic spread were observed between different populations of Aedes aegypti. Copyright © 2018. Published by Elsevier Inc.
A recent bottleneck of Y chromosome diversity coincides with a global change in culture.
Karmin, Monika; Saag, Lauri; Vicente, Mário; Wilson Sayres, Melissa A; Järve, Mari; Talas, Ulvi Gerst; Rootsi, Siiri; Ilumäe, Anne-Mai; Mägi, Reedik; Mitt, Mario; Pagani, Luca; Puurand, Tarmo; Faltyskova, Zuzana; Clemente, Florian; Cardona, Alexia; Metspalu, Ene; Sahakyan, Hovhannes; Yunusbayev, Bayazit; Hudjashov, Georgi; DeGiorgio, Michael; Loogväli, Eva-Liis; Eichstaedt, Christina; Eelmets, Mikk; Chaubey, Gyaneshwer; Tambets, Kristiina; Litvinov, Sergei; Mormina, Maru; Xue, Yali; Ayub, Qasim; Zoraqi, Grigor; Korneliussen, Thorfinn Sand; Akhatova, Farida; Lachance, Joseph; Tishkoff, Sarah; Momynaliev, Kuvat; Ricaut, François-Xavier; Kusuma, Pradiptajati; Razafindrazaka, Harilanto; Pierron, Denis; Cox, Murray P; Sultana, Gazi Nurun Nahar; Willerslev, Rane; Muller, Craig; Westaway, Michael; Lambert, David; Skaro, Vedrana; Kovačevic, Lejla; Turdikulova, Shahlo; Dalimova, Dilbar; Khusainova, Rita; Trofimova, Natalya; Akhmetova, Vita; Khidiyatova, Irina; Lichman, Daria V; Isakova, Jainagul; Pocheshkhova, Elvira; Sabitov, Zhaxylyk; Barashkov, Nikolay A; Nymadawa, Pagbajabyn; Mihailov, Evelin; Seng, Joseph Wee Tien; Evseeva, Irina; Migliano, Andrea Bamberg; Abdullah, Syafiq; Andriadze, George; Primorac, Dragan; Atramentova, Lubov; Utevska, Olga; Yepiskoposyan, Levon; Marjanovic, Damir; Kushniarevich, Alena; Behar, Doron M; Gilissen, Christian; Vissers, Lisenka; Veltman, Joris A; Balanovska, Elena; Derenko, Miroslava; Malyarchuk, Boris; Metspalu, Andres; Fedorova, Sardana; Eriksson, Anders; Manica, Andrea; Mendez, Fernando L; Karafet, Tatiana M; Veeramah, Krishna R; Bradman, Neil; Hammer, Michael F; Osipova, Ludmila P; Balanovsky, Oleg; Khusnutdinova, Elza K; Johnsen, Knut; Remm, Maido; Thomas, Mark G; Tyler-Smith, Chris; Underhill, Peter A; Willerslev, Eske; Nielsen, Rasmus; Metspalu, Mait; Villems, Richard; Kivisild, Toomas
2015-04-01
It is commonly thought that human genetic diversity in non-African populations was shaped primarily by an out-of-Africa dispersal 50-100 thousand yr ago (kya). Here, we present a study of 456 geographically diverse high-coverage Y chromosome sequences, including 299 newly reported samples. Applying ancient DNA calibration, we date the Y-chromosomal most recent common ancestor (MRCA) in Africa at 254 (95% CI 192-307) kya and detect a cluster of major non-African founder haplogroups in a narrow time interval at 47-52 kya, consistent with a rapid initial colonization model of Eurasia and Oceania after the out-of-Africa bottleneck. In contrast to demographic reconstructions based on mtDNA, we infer a second strong bottleneck in Y-chromosome lineages dating to the last 10 ky. We hypothesize that this bottleneck is caused by cultural changes affecting variance of reproductive success among males. © 2015 Karmin et al.; Published by Cold Spring Harbor Laboratory Press.
Expert systems as applied to bridges : knowledge acquisition phase : final report.
DOT National Transportation Integrated Search
1987-01-01
Presented in this report is a detailed description of the procedure to be followed to develop a knowledge-based computerized expert system for determining whether to rehabilitate, improve, replace, abandon, or just to routinely maintain an old highwa...
Motivational Design in Information Literacy Instruction
ERIC Educational Resources Information Center
Hess, Amanda Nichols
2015-01-01
Motivational design theory complements instructional design theory and, when used together, both principles can affect learning, knowledge acquisition, and knowledge retention. In information literacy instruction, motivational design exists throughout the appropriate standards documents. However, there is limited current research on the best…
ERIC Educational Resources Information Center
Mazoue, James G.
2012-01-01
Four converging trends are undermining land-based campuses as the preeminent source of knowledge acquisition and certification. The emergence of the learning sciences, the wikification of knowledge, the unbundling of faculty roles, and the migration of learning online are driving fundamental institutional change toward location-independent…
A Probabilistic Ontology Development Methodology
2014-06-01
Test, and Evaluation; Acquisition; and Planning and Marketing ," in Handbook of Systems Engineering and Management .: John Wiley & Sons, 2009, pp...Intelligence and knowledge management . However, many real world problems in these disciplines are burdened by incomplete information and other sources...knowledge engineering, Artificial Intelligence and knowledge management . However, many real world problems in these disciplines are burdened by
ERIC Educational Resources Information Center
Evans, Mary Ann; Bell, Michelle; Shaw, Deborah; Moretti, Shelley; Page, Jodi
2006-01-01
In this study 149 kindergarten children were assessed for knowledge of letter names and letter sounds, phonological awareness, and cognitive abilities. Through this it examined child and letter characteristics influencing the acquisition of alphabetic knowledge in a naturalistic context, the relationship between letter-sound knowledge and…
ERIC Educational Resources Information Center
Starbek, P.; Erjavec, M. Starcic; Peklaj, C.
2010-01-01
The main goal of this study was to explore whether the use of multimedia in genetics instruction contributes more to students' knowledge and comprehension than other instructional modes. We were also concerned with the influence of different instructional modes on the retention of knowledge and comprehension. In a quasi-experimental design, four…
ERIC Educational Resources Information Center
Ebadi, Mandana Rohollahzadeh; Saad, Mohd Rashid Mohd; Abedalaziz, Nabil
2014-01-01
The issue of error correction remains controversial in recent years due to the different positions of interface toward implicit and explicit knowledge of ESL learners. This study looks at the impacts of implicit corrective feedback in the form of recast on implicit and explicit knowledge of adult ESL learners. In an experimental study,…
ERIC Educational Resources Information Center
Schwaighofer, Matthias; Bühner, Markus; Fischer, Frank
2016-01-01
Worked examples have proven to be effective for knowledge acquisition compared with problem solving, particularly when prior knowledge is low (e.g., Kalyuga, 2007). However, in addition to prior knowledge, executive functions and fluid intelligence might be potential moderators of the effectiveness of worked examples. The present study examines…
Examining the Acquisition of Vocabulary Knowledge Depth among Preschool Students
ERIC Educational Resources Information Center
Hadley, Elizabeth B.; Dickinson, David K.; Hirsh-Pasek, Kathy; Golinkoff, Roberta Michnick; Nesbitt, Kimberly T.
2016-01-01
Well-developed lexical representations are important for reading comprehension, but there have been no prior attempts to track growth in the depth of knowledge of particular words. This article examines increases in depth of vocabulary knowledge in 4-5-year-old preschool students (n = 240) who participated in a vocabulary intervention that taught…
ERIC Educational Resources Information Center
Land, Susan M.; Draper, Darryl C.; Ma, Ziyan; Hsieh, Hsiu-Wei; Smith, Brian K.; Jordan, Robert
2009-01-01
Current approaches to workplace learning emphasize designing communities of practice that are intended to support both formal and informal knowledge acquisition. This article presents the design and research of a knowledge-based community of practice for Subaru, based on principles outlined by Scardamalia (2002) and Zhang, Scardamalia, Lamon,…
Measuring Explicit and Implicit Knowledge: A Psychometric Study in SLA
ERIC Educational Resources Information Center
Ebadi, Mandana Rohollahzadeh; Abedalaziz, Nabeel; Saad, Mohd Rashid Mohd
2015-01-01
Lack of valid means of measuring explicit and implicit knowledge in acquisition of second language is a concern issue in investigations of explicit and implicit learning. This paper endeavors to validate the use of four tests (i.e., Untimed Judgment Grammatical Test, UJGT; Test of Metalinguistic Knowledge, TMK; Elicited Oral Imitation Test, EOIT;…
ERIC Educational Resources Information Center
König, Johannes
2013-01-01
Teacher education systems worldwide are confronted with the essential question of how to foster both future teachers' theoretical and practical knowledge and to adequately enable future teachers to connect their theoretical and practical knowledge for teaching. This article investigates how future teachers acquire general pedagogical knowledge…
The Impact of Incorrect Examples on Learning Fractions: A Field Experiment with 6th Grade Students
ERIC Educational Resources Information Center
Heemsoth, Tim; Heinze, Aiso
2014-01-01
Educational research indicates that error reflection, especially reflection on incorrect examples, has a positive effect on knowledge acquisition. The benefit of error reflections might be explained by the extended knowledge of incorrect strategies and concepts (negative knowledge) which fosters the learning of new content. In a field experiment…
ERIC Educational Resources Information Center
Hodges, Michael
2015-01-01
For many decades, children and adolescents have had a deficient level of health-related fitness knowledge (HRFK). This is worrisome, since HRFK acquisition has been found to be fundamental for individuals' decision-making as it relates to healthy living. Consequently, Knowledge in Action (KIA) fitness was developed to offer elementary teachers an…
Measuring University-Level L2 Learners' Implicit and Explicit Linguistic Knowledge
ERIC Educational Resources Information Center
Zhang, Runhan
2015-01-01
Although many theoretical issues revolving around implicit and explicit knowledge in second language (L2) acquisition hinge on the ability to measure these two types of knowledge, few empirical studies have attempted to do so. However, R. Ellis (2005) did develop a battery of tests intended to provide relatively separate measures. This study aims…
Results of Using Writing Tasks To Enhance Fourth-Grade Children's Acquisition of Fraction Knowledge.
ERIC Educational Resources Information Center
Sharp, Janet M.
Schumacher and Nash (1991) theorize that writing provides an avenue for people to reorganize their knowledge. Kieren (1988) is one of several researchers who theorize that children's school fraction experiences should begin with personal knowledge of fractions. The purpose of this study was to determine whether or not children who engaged in…
ERIC Educational Resources Information Center
Engelmann, Tanja
2014-01-01
For effective communication and collaboration in learning situations, it is important to know what the collaboration partners know. However, the acquisition of this knowledge is difficult, especially in collaborating groups with spatially distributed members. One solution is the "Knowledge and Information Awareness" approach developed by…
Asynchronous web-based learning, a practical method to enhance teaching in emergency medicine.
Pourmand, Ali; Lucas, Raymond; Nouraie, Mehdi
2013-03-01
Abstract Objective: To compare medical knowledge acquisition among emergency medicine (EM) residents who attend weekly core content lectures with those absent but asynchronously viewing the same lectures in a Web-based electronic platform. During the study period all EM residents attending or absent from weekly educational conferences were given a quiz on the covered material. During Phase 1, absentees were not given supplemental educational content for missed lectures. During Phase 2, absentees were sent a link to an online multimedia module containing an audiovisual recording of the actual missed lecture with presentation slides. Scores between attendees and absentees during both phases were compared using a repeated-measures analysis to evaluate the effect of the supplemental online module on knowledge acquisition. Thirty-nine EM residents (equally distributed in postgraduate years 1-4) were studied during a 15-week period. Overall and after adjusting for sex and postgraduate year level, both lecture attendance (b=27; 95% confidence interval, 22-32; p<0.0001) and Web-based learning (b=32; 95% confidence interval, 26-37; p<0.0001) were associated with significant increases in test scores compared with residents who were absent and not receiving supplemental Web-based learning. Neither the self-perceived level of mastery with the lecture topic nor the amount of reported reading was found to be a predictor of test scores. In an EM residency program, asynchronous Web-based learning may result in medical knowledge acquisition similar to or better than attending traditional core content lectures. The percentage of curriculum delivery by asynchronous learning that may be used to achieve overall terminal learning objectives in medical knowledge acquisition requires further study.
Sánchez-Ledesma, M J; Juanes, J A; Sáncho, C; Alonso-Sardón, M; Gonçalves, J
2016-06-01
The training of medical students demands practice of skills in scenarios as close as possible to real ones that on one hand ensure acquisition of competencies, and on the other, avoid putting patients at risk. This study shows the practicality of using high definition mannequins (SimMan 3G) in scenarios of first attention in neurological emergencies so that medical students at the Faculty of Medicine of the University of Salamanca could acquire specific and transversal competencies. The repetition of activities in simulation environments significantly facilitates the acquisition of competencies by groups of students (p < 00.5). The greatest achievements refer to skills whereas the competencies that demand greater integration of knowledge seem to need more time or new sessions. This is what happens with the competencies related to the initial diagnosis, the requesting of tests and therapeutic approaches, which demand greater theoretical knowledge.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dasgupta, Aritra; Poco, Jorge; Bertini, Enrico
2016-01-01
The gap between large-scale data production rate and the rate of generation of data-driven scientific insights has led to an analytical bottleneck in scientific domains like climate, biology, etc. This is primarily due to the lack of innovative analytical tools that can help scientists efficiently analyze and explore alternative hypotheses about the data, and communicate their findings effectively to a broad audience. In this paper, by reflecting on a set of successful collaborative research efforts between with a group of climate scientists and visualization researchers, we introspect how interactive visualization can help reduce the analytical bottleneck for domain scientists.
Uncovering clinical knowledge and caring practices.
Feldman, M E
1993-06-01
Narrative storytelling is a means by which knowledge embedded in nursing practice is uncovered and examined. Benner uses this method to study and explore skill acquisition and experience-based knowledge in nursing practice. By sharing these stories, knowledge that is unique to the experienced clinician is preserved and extended. The narrative presented here describes the expert coaching, discretionary judgment, and skilled involvement in the care of a patient in the PACU.
The elements of design knowledge capture
NASA Technical Reports Server (NTRS)
Freeman, Michael S.
1988-01-01
This paper will present the basic constituents of a design knowledge capture effort. This will include a discussion of the types of knowledge to be captured in such an effort and the difference between design knowledge capture and more traditional knowledge base construction. These differences include both knowledge base structure and knowledge acquisition approach. The motivation for establishing a design knowledge capture effort as an integral part of major NASA programs will be outlined, along with the current NASA position on that subject. Finally the approach taken in design knowledge capture for Space Station will be contrasted with that used in the HSTDEK project.
Non-stochastic reprogramming from a privileged somatic cell state
Guo, Shangqin; Zi, Xiaoyuan; Schulz, Vincent P.; Cheng, Jijun; Zhong, Mei; Koochaki, Sebastian H.J.; Megyola, Cynthia M.; Pan, Xinghua; Heydari, Kartoosh; Weissman, Sherman M.; Gallagher, Patrick G.; Krause, Diane S.; Fan, Rong; Lu, Jun
2014-01-01
SUMMARY Reprogramming somatic cells to induced pluripotency by Yamanaka factors is usually slow and inefficient, and is thought to be a stochastic process. We identified a privileged somatic cell state, from which acquisition of pluripotency could occur in a non-stochastic manner. Subsets of murine hematopoietic progenitors are privileged, whose progeny cells predominantly adopt the pluripotent fate with activation of endogenous Oct4 locus after 4–5 divisions in reprogramming conditions. Privileged cells display an ultrafast cell cycle of ~8 hours. In fibroblasts, a subpopulation cycling at a similar ultrafast speed is observed after 6 days of factor expression, and is increased by p53-knockdown. This ultrafast-cycling population accounts for >99% of the bulk reprogramming activity in wildtype or p53-knockdown fibroblasts. Our data demonstrate that the stochastic nature of reprogramming can be overcome in a privileged somatic cell state, and suggest that cell cycle acceleration toward a critical threshold is an important bottleneck for reprogramming. PMID:24486105
Distributed parallel computing in stochastic modeling of groundwater systems.
Dong, Yanhui; Li, Guomin; Xu, Haizhen
2013-03-01
Stochastic modeling is a rapidly evolving, popular approach to the study of the uncertainty and heterogeneity of groundwater systems. However, the use of Monte Carlo-type simulations to solve practical groundwater problems often encounters computational bottlenecks that hinder the acquisition of meaningful results. To improve the computational efficiency, a system that combines stochastic model generation with MODFLOW-related programs and distributed parallel processing is investigated. The distributed computing framework, called the Java Parallel Processing Framework, is integrated into the system to allow the batch processing of stochastic models in distributed and parallel systems. As an example, the system is applied to the stochastic delineation of well capture zones in the Pinggu Basin in Beijing. Through the use of 50 processing threads on a cluster with 10 multicore nodes, the execution times of 500 realizations are reduced to 3% compared with those of a serial execution. Through this application, the system demonstrates its potential in solving difficult computational problems in practical stochastic modeling. © 2012, The Author(s). Groundwater © 2012, National Ground Water Association.
TomoMiner and TomoMinerCloud: A software platform for large-scale subtomogram structural analysis
Frazier, Zachary; Xu, Min; Alber, Frank
2017-01-01
SUMMARY Cryo-electron tomography (cryoET) captures the 3D electron density distribution of macromolecular complexes in close to native state. With the rapid advance of cryoET acquisition technologies, it is possible to generate large numbers (>100,000) of subtomograms, each containing a macromolecular complex. Often, these subtomograms represent a heterogeneous sample due to variations in structure and composition of a complex in situ form or because particles are a mixture of different complexes. In this case subtomograms must be classified. However, classification of large numbers of subtomograms is a time-intensive task and often a limiting bottleneck. This paper introduces an open source software platform, TomoMiner, for large-scale subtomogram classification, template matching, subtomogram averaging, and alignment. Its scalable and robust parallel processing allows efficient classification of tens to hundreds of thousands of subtomograms. Additionally, TomoMiner provides a pre-configured TomoMinerCloud computing service permitting users without sufficient computing resources instant access to TomoMiners high-performance features. PMID:28552576
Evaluation of PROforma as a language for implementing medical guidelines in a practical context
Sutton, David R; Taylor, Paul; Earle, Kenneth
2006-01-01
Background PROforma is one of several languages that allow clinical guidelines to be expressed in a computer-interpretable manner. How these languages should be compared, and what requirements they should meet, are questions that are being actively addressed by a community of interested researchers. Methods We have developed a system to allow hypertensive patients to be monitored and assessed without visiting their GPs (except in the most urgent cases). Blood pressure measurements are performed at the patients' pharmacies and a web-based system, created using PROforma, makes recommendations for continued monitoring, and/or changes in medication. The recommendations and measurements are transmitted electronically to a practitioner with authority to issue and change prescriptions. We evaluated the use of PROforma during the knowledge acquisition, analysis, design and implementation of this system. The analysis focuses on the logical adequacy, heuristic power, notational convenience, and explanation support provided by the PROforma language. Results PROforma proved adequate as a language for the implementation of the clinical reasoning required by this project. However a lack of notational convenience led us to use UML activity diagrams, rather than PROforma process descriptions, to create the models that were used during the knowledge acquisition and analysis phases of the project. These UML diagrams were translated into PROforma during the implementation of the project. Conclusion The experience accumulated during this study highlighted the importance of structure preserving design, that is to say that the models used in the design and implementation of a knowledge-based system should be structurally similar to those created during knowledge acquisition and analysis. Ideally the same language should be used for all of these models. This means that great importance has to be attached to the notational convenience of these languages, by which we mean the ease with which they can be read, written, and understood by human beings. The importance of notational convenience arises from the fact that a language used during knowledge acquisition and analysis must be intelligible to the potential users of a system, and to the domain experts who provide the knowledge that will be used in its construction. PMID:16597341
Evaluation of PROforma as a language for implementing medical guidelines in a practical context.
Sutton, David R; Taylor, Paul; Earle, Kenneth
2006-04-05
PROforma is one of several languages that allow clinical guidelines to be expressed in a computer-interpretable manner. How these languages should be compared, and what requirements they should meet, are questions that are being actively addressed by a community of interested researchers. We have developed a system to allow hypertensive patients to be monitored and assessed without visiting their GPs (except in the most urgent cases). Blood pressure measurements are performed at the patients' pharmacies and a web-based system, created using PROforma, makes recommendations for continued monitoring, and/or changes in medication. The recommendations and measurements are transmitted electronically to a practitioner with authority to issue and change prescriptions. We evaluated the use of PROforma during the knowledge acquisition, analysis, design and implementation of this system. The analysis focuses on the logical adequacy, heuristic power, notational convenience, and explanation support provided by the PROforma language. PROforma proved adequate as a language for the implementation of the clinical reasoning required by this project. However a lack of notational convenience led us to use UML activity diagrams, rather than PROforma process descriptions, to create the models that were used during the knowledge acquisition and analysis phases of the project. These UML diagrams were translated into PROforma during the implementation of the project. The experience accumulated during this study highlighted the importance of structure preserving design, that is to say that the models used in the design and implementation of a knowledge-based system should be structurally similar to those created during knowledge acquisition and analysis. Ideally the same language should be used for all of these models. This means that great importance has to be attached to the notational convenience of these languages, by which we mean the ease with which they can be read, written, and understood by human beings. The importance of notational convenience arises from the fact that a language used during knowledge acquisition and analysis must be intelligible to the potential users of a system, and to the domain experts who provide the knowledge that will be used in its construction.
Mule deer and pronghorn migration in western Wyoming
Sawyer, H.; Lindzey, F.; McWhirter, D.
2005-01-01
Migratory mule deer (Odocoileus hemionus) and pronghorn (Antilocapra americana) populations rely on seasonal ranges to meet their annual nutritional and energetic requirements. Because seasonal ranges often occur great distances apart and across a mix of vegetation types and land ownership, maintaining migration corridors to and from these ranges can be difficult, especially if managers do not have detailed information on mule deer and pronghorn seasonal movements. We captured, radiomarked, and monitored mule deer (n = 171) and pronghorn (n = 34) in western Wyoming to document seasonal distribution patterns and migration routes. Mule deer and pronghorn migrated 20-158 km and 116-258 km, respectively, between seasonal ranges. These distances represented the longest recorded migrations for either species. We identified a number of bottlenecks along the migration routes of mule deer and pronghorn, but the most critical appeared to be the 1.6-km-wide Trapper's Point bottleneck, which was used by both mule deer and pronghorn during their spring and autumn migrations. Housing developments and roadways apparently have reduced the effective width of this bottleneck to <0.8 km. We estimate 2,500-3,500 mule deer and 1,500-2,000 pronghorn move through the bottleneck twice a year during spring and autumn migrations. Identification and protection of migration corridors and bottlenecks will be necessary to maintain mule deer and pronghorn populations throughout their range.
Baker, Ulrika; Okuga, Monica; Waiswa, Peter; Manzi, Fatuma; Peterson, Stefan; Hanson, Claudia
2015-06-01
To identify and compare implementation bottlenecks for effective coverage of screening for syphilis, HIV, and anemia in antenatal care in rural Tanzania and Uganda; and explore the underlying determinants and perceived solutions to overcome these bottlenecks. In this multiple case study, we analyzed data collected as part of the Expanded Quality Management Using Information Power (EQUIP) project between November 2011 and April 2014. Indicators from household interviews (n=4415 mothers) and health facility surveys (n=122) were linked to estimate coverage in stages of implementation between which bottlenecks can be identified. Key informant interviews (n=15) were conducted to explore underlying determinants and analyzed using a framework approach. Large differences in implementation were found within and between countries. Availability and effective coverage was significantly lower for all tests in Uganda compared with Tanzania. Syphilis screening had the lowest availability and effective coverage in both countries. The main implementation bottleneck was poor availability of tests and equipment. Key informant interviews validated these findings and perceived solutions included the need for improved procurement at the central level. Our findings reinforce essential screening as a missed opportunity, caused by a lack of integration of funding and support for comprehensive antenatal care programs. Copyright © 2015 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
Structural Representations in Knowledge Acquisition.
ERIC Educational Resources Information Center
Gonzalvo, Pilar; And Others
1994-01-01
Multidimensional scaling (MDS) and Pathfinder techniques for assessing changes in the structural representation of a knowledge domain were studied with relatedness ratings collected from 72 Spanish college students. Comparison of student and expert similarity measures indicate that MDS and graph theoretic approaches are valid techniques. (SLD)
Higher Education Exchange 2006
ERIC Educational Resources Information Center
Brown, David W., Ed.; Witte, Deborah, Ed.
2006-01-01
Contributors to this issue of the Higher Education Exchange debate the issues around knowledge production, discuss the acquisition of deliberative skills for democracy, and examine how higher education prepares, or does not prepare, students for citizenship roles. Articles include: (1) "Foreword" (Deborah Witte); (2) "Knowledge,…
Sexual Knowledge Acquisition and Retention for Individuals with Autism
ERIC Educational Resources Information Center
Pask, Liza; Hughes, Tammy L.; Sutton, Lawrence R.
2016-01-01
"Healthy Relationships & Autism" is a developmentally sequenced, manualized intervention intended for children and adolescents with an autism spectrum disorder (ASD). The curriculum is designed to facilitate healthy interpersonal relationships; three modules cover personal hygiene, sexual knowledge, and a variety of productive…
Evaluation of virtual microscopy in medical histology teaching.
Mione, Sylvia; Valcke, Martin; Cornelissen, Maria
2013-01-01
Histology stands as a major discipline in the life science curricula, and the practice of teaching it is based on theoretical didactic strategies along with practical training. Traditionally, students achieve practical competence in this subject by learning optical microscopy. Today, students can use newer information and communication technologies in the study of digital microscopic images. A virtual microscopy program was recently introduced at Ghent University. Since little empirical evidence is available concerning the impact of virtual microscopy (VM) versus optical microscopy (OM) on the acquisition of histology knowledge, this study was set up in the Faculty of Medicine and Health Sciences. A pretest-post test and cross-over design was adopted. In the first phase, the experiment yielded two groups in a total population of 199 students, Group 1 performing the practical sessions with OM versus Group 2 performing the same sessions with VM. In the second phase, the research subjects switched conditions. The prior knowledge level of all research subjects was assessed with a pretest. Knowledge acquisition was measured with a post test after each phase (T1 and T2). Analysis of covariance was carried out to study the differential gain in knowledge at T1 and T2, considering the possible differences in prior knowledge at the start of the study. The results pointed to non-significant differences at T1 and at T2. This supports the assumption that the acquisition of the histology knowledge is independent of the microscopy representation mode (VM versus OM) of the learning material. The conclusion that VM is equivalent to OM offers new directions in view of ongoing innovations in medical education technology. Copyright © 2013 American Association of Anatomists.
Viewer Perspective Affects Central Bottleneck Requirements in Spatial Translation Tasks
ERIC Educational Resources Information Center
Franz, Elizabeth A.; Sebastian, Alexandra; Hust, Christina; Norris, Tom
2008-01-01
A psychological refractory period (PRP) approach and the locus of slack logic were applied to examine the novel question of whether spatial translation processes can begin before the central bottleneck when effector or noneffector stimuli are processed from an egocentric (viewer-centered) perspective. In single tasks, trials requiring spatial…
Colé, Pascale; Cavalli, Eddy; Duncan, Lynne G.; Theurel, Anne; Gentaz, Edouard; Sprenger-Charolles, Liliane; El-Ahmadi, Abdessadek
2018-01-01
Children from low-SES families are known to show delays in aspects of language development which underpin reading acquisition such as vocabulary and listening comprehension. Research on the development of morphological skills in this group is scarce, and no studies exist in French. The present study investigated the involvement of morphological knowledge in the very early stages of reading acquisition (decoding), before reading comprehension can be reliably assessed. We assessed listening comprehension, receptive vocabulary, phoneme awareness, morphological awareness as well as decoding, word reading and non-verbal IQ in 703 French first-graders from low-SES families after 3 months of formal schooling (November). Awareness of derivational morphology was assessed using three oral tasks: Relationship Judgment (e.g., do these words belong to the same family or not? heat-heater … ham-hammer); Lexical Sentence Completion [e.g., Someone who runs is a …? (runner)]; and Non-lexical Sentence Completion [e.g., Someone who lums is a…? (lummer)]. The tasks differ on implicit/explicit demands and also tap different kinds of morphological knowledge. The Judgement task measures the phonological and semantic properties of the morphological relationship and the Sentence Completion tasks measure knowledge of morphological production rules. Data were processed using a graphical modeling approach which offers key information about how skills known to be involved in learning to read are organized in memory. This modeling approach was therefore useful in revealing a potential network which expresses the conditional dependence structure between skills, after which recursive structural equation modeling was applied to test specific hypotheses. Six main conclusions can be drawn from these analyses about low SES reading acquisition: (1) listening comprehension is at the heart of the reading acquisition process; (2) word reading depends directly on phonemic awareness and indirectly on listening comprehension; (3) decoding depends on word reading; (4) Morphological awareness and vocabulary have an indirect influence on word reading via both listening comprehension and phoneme awareness; (5) the components of morphological awareness assessed by our tasks have independent relationships with listening comprehension; and (6) neither phonemic nor morphological awareness influence vocabulary directly. The implications of these results with regard to early reading acquisition among low SES groups are discussed. PMID:29725313
Colé, Pascale; Cavalli, Eddy; Duncan, Lynne G; Theurel, Anne; Gentaz, Edouard; Sprenger-Charolles, Liliane; El-Ahmadi, Abdessadek
2018-01-01
Children from low-SES families are known to show delays in aspects of language development which underpin reading acquisition such as vocabulary and listening comprehension. Research on the development of morphological skills in this group is scarce, and no studies exist in French. The present study investigated the involvement of morphological knowledge in the very early stages of reading acquisition (decoding), before reading comprehension can be reliably assessed. We assessed listening comprehension, receptive vocabulary, phoneme awareness, morphological awareness as well as decoding, word reading and non-verbal IQ in 703 French first-graders from low-SES families after 3 months of formal schooling (November). Awareness of derivational morphology was assessed using three oral tasks: Relationship Judgment (e.g., do these words belong to the same family or not? heat-heater … ham-hammer); Lexical Sentence Completion [e.g., Someone who runs is a …? (runner)]; and Non-lexical Sentence Completion [e.g., Someone who lums is a…? (lummer)]. The tasks differ on implicit/explicit demands and also tap different kinds of morphological knowledge. The Judgement task measures the phonological and semantic properties of the morphological relationship and the Sentence Completion tasks measure knowledge of morphological production rules. Data were processed using a graphical modeling approach which offers key information about how skills known to be involved in learning to read are organized in memory. This modeling approach was therefore useful in revealing a potential network which expresses the conditional dependence structure between skills, after which recursive structural equation modeling was applied to test specific hypotheses. Six main conclusions can be drawn from these analyses about low SES reading acquisition: (1) listening comprehension is at the heart of the reading acquisition process; (2) word reading depends directly on phonemic awareness and indirectly on listening comprehension; (3) decoding depends on word reading; (4) Morphological awareness and vocabulary have an indirect influence on word reading via both listening comprehension and phoneme awareness; (5) the components of morphological awareness assessed by our tasks have independent relationships with listening comprehension; and (6) neither phonemic nor morphological awareness influence vocabulary directly. The implications of these results with regard to early reading acquisition among low SES groups are discussed.
Language and Literacy Acquisition through Parental Mediation in American Sign Language
ERIC Educational Resources Information Center
Bailes, Cynthia Neese; Erting, Lynne C.; Thumann-Prezioso, Carlene; Erting, Carol J.
2009-01-01
This longitudinal case study examined the language and literacy acquisition of a Deaf child as mediated by her signing Deaf parents during her first three years of life. Results indicate that the parents' interactions with their child were guided by linguistic and cultural knowledge that produced an intuitive use of child-directed signing (CDSi)…
Application Features of Language Acquisition Assessment System in Kazakhstan: KAZTEST
ERIC Educational Resources Information Center
Dinayeva, Bekzat B.; Sapina, Sabira M.; Utanova, Aizada K.; Aitova, Nurlykhan N.
2016-01-01
The article deals with the analysis of peculiarities of language acquisition assessment system in Kazakhstan--KAZTEST. The author pays attention to the role of control as a way of assessment students' skills, habits and knowledge. In addition, author determined the place and functions of tests as a form of control. The author explores the…
ERIC Educational Resources Information Center
Kennedy, Michael J.; Wagner, Dana; Stegall, Joanna; Lembke, Erica; Miciak, Jeremy; Alves, Kat D.; Brown, Tiara; Driver, Melissa K.; Hirsch, Shanna Eisner
2016-01-01
Given the significant literature supporting the use of curriculum-based measurement (CBM) for data-based decision making, it is critical that teacher candidates learn about it prior to student teaching and entry into the field as full-time teachers. The authors of this study used a content acquisition podcast (CAP), a multimedia-based…
An Introduction to X Window Application Development
1992-03-23
Acquisition and Policy Evaluation program using Cognitive Feed- back ( ESKAPE /CF) from the SunView windowing system to X Window. The new application...the generic X Window System. This thesis converts an Expert System Knowledge Acquisition and Policy Evaluation program using Cognitive Feedback ( ESKAPE ...15 IV. XESKAPE/CF: THE X WINDOW VERSION OF ESKAPE /CF ........................ 16 A. FUNCTIONAL COMPARISON TO
Models of Vocabulary Acquisition: Direct Tests and Text-Derived Simulations of Vocabulary Growth
ERIC Educational Resources Information Center
Biemiller, Andrew; Rosenstein, Mark; Sparks, Randall; Landauer, Thomas K.; Foltz, Peter W.
2014-01-01
Determining word meanings that ought to be taught or introduced is important for educators. A sequence for vocabulary growth can be inferred from many sources, including testing children's knowledge of word meanings at various ages, predicting from print frequency, or adult-recalled Age of Acquisition. A new approach, Word Maturity, is based on…
LF "Wh"-Movement and Its Locality Constraints in Child Japanese
ERIC Educational Resources Information Center
Sugisaki, Koji
2012-01-01
In natural languages, the mapping from surface form to meaning is often quite complex, and hence the acquisition of the phenomena at the boundary between syntax and semantics has been one of the central issues in current acquisition research. This study addresses the issue of whether children have adult-like knowledge of LF "wh"-movement and its…
ERIC Educational Resources Information Center
Ponniah, Joseph
2011-01-01
The Comprehension Hypothesis (CH) is the most powerful hypothesis in the field of Second Language Acquisition despite the presence of the rivals the skill-building hypothesis, the output hypothesis, and the interaction hypothesis. The competing hypotheses state that consciously learned linguistic knowledge is a necessary step for the development…
Processing Strategies by Beginning L2 Learners of English and Spanish: A Crosslinguistic Study
ERIC Educational Resources Information Center
Brandl, Anel
2013-01-01
A central issue in second language acquisition (SLA) research is the relationship between morphosyntactic and lexical-semantic knowledge among L2 learners. It has been proposed that, L2 language acquisition starts with transfer of L1 semantic and morphosyntactic processing strategies; however, it has been observed that, at lower proficiency…
Danuso, Francesco
2017-12-22
A major bottleneck for improving the governance of complex systems, rely on our ability to integrate different forms of knowledge into a decision support system (DSS). Preliminary aspects are the classification of different types of knowledge (a priori or general, a posteriori or specific, with uncertainty, numerical, textual, algorithmic, complete/incomplete, etc.), the definition of ontologies for knowledge management and the availability of proper tools like continuous simulation models, event driven models, statistical approaches, computational methods (neural networks, evolutionary optimization, rule based systems etc.) and procedure for textual documentation. Following these views at University of Udine, a computer language (SEMoLa, Simple, Easy Modelling Language) for knowledge integration has been developed. SEMoLa can handle models, data, metadata and textual knowledge; it implements and extends the system dynamics ontology (Forrester, 1968; Jørgensen, 1994) in which systems are modelled by the concepts of material, group, state, rate, parameter, internal and external events and driving variables. As an example, a SEMoLa model to improve management and sustainability (economical, energetic, environmental) of the agricultural farms is presented. The model (X-Farm) simulates a farm in which cereal and forage yield, oil seeds, milk, calves and wastes can be sold or reused. X-Farm is composed by integrated modules describing fields (crop and soil), feeds and materials storage, machinery management, manpower management, animal husbandry, economic and energetic balances, seed oil extraction, manure and wastes management, biogas production from animal wastes and biomasses.
Advanced Software Development Workstation Project
NASA Technical Reports Server (NTRS)
Lee, Daniel
1989-01-01
The Advanced Software Development Workstation Project, funded by Johnson Space Center, is investigating knowledge-based techniques for software reuse in NASA software development projects. Two prototypes have been demonstrated and a third is now in development. The approach is to build a foundation that provides passive reuse support, add a layer that uses domain-independent programming knowledge, add a layer that supports the acquisition of domain-specific programming knowledge to provide active support, and enhance maintainability and modifiability through an object-oriented approach. The development of new application software would use specification-by-reformulation, based on a cognitive theory of retrieval from very long-term memory in humans, and using an Ada code library and an object base. Current tasks include enhancements to the knowledge representation of Ada packages and abstract data types, extensions to support Ada package instantiation knowledge acquisition, integration with Ada compilers and relational databases, enhancements to the graphical user interface, and demonstration of the system with a NASA contractor-developed trajectory simulation package. Future work will focus on investigating issues involving scale-up and integration.
Simulation-based local anaesthesia teaching enhances learning outcomes.
Marei, H F; Al-Jandan, B A
2013-02-01
The aim of this study was to evaluate the efficacy of simulation-based local anaesthesia teaching strategies compared to the traditional classroom lecture format on the acquisition of knowledge by students. Two groups of 10 students each were included in our study. Each of the dental students was enrolled in their third year of the programme. None of the students had ever received instructions in local anaesthesia. Group I received a 45-min instructional module that was delivered in the classroom in the traditional PowerPoint lecture format. Group II received a 45-min instructional module in the simulation laboratory as a short tutorial that was followed by an integrated practical demonstration and a hands-on practice session using local anaesthesia simulation phantoms. An identical 15-question multiple-choice test was used to test student knowledge acquisition at the end of the given session. There was a statistically significant difference between the two groups, as the participants in group II had higher score results than those of group I. In contrast to the traditional classroom lecture format, simulation-based local anaesthesia teaching is an effective tool to enhance the acquisition of theoretical knowledge by students. © 2012 John Wiley & Sons A/S.
Tomesko, Jennifer; Touger-Decker, Riva; Dreker, Margaret; Zelig, Rena; Parrott, James Scott
2017-01-01
Purpose: To explore knowledge and skill acquisition outcomes related to learning physical examination (PE) through computer-assisted instruction (CAI) compared with a face-to-face (F2F) approach. Method: A systematic literature review and meta-analysis published between January 2001 and December 2016 was conducted. Databases searched included Medline, Cochrane, CINAHL, ERIC, Ebsco, Scopus, and Web of Science. Studies were synthesized by study design, intervention, and outcomes. Statistical analyses included DerSimonian-Laird random-effects model. Results: In total, 7 studies were included in the review, and 5 in the meta-analysis. There were no statistically significant differences for knowledge (mean difference [MD] = 5.39, 95% confidence interval [CI]: −2.05 to 12.84) or skill acquisition (MD = 0.35, 95% CI: −5.30 to 6.01). Conclusions: The evidence does not suggest a strong consistent preference for either CAI or F2F instruction to teach students/trainees PE. Further research is needed to identify conditions which examine knowledge and skill acquisition outcomes that favor one mode of instruction over the other. PMID:29349338
ERIC Educational Resources Information Center
Pearl, Lisa S.
2011-01-01
Parametric systems have been proposed as models of how humans represent knowledge about language, motivated in part as a way to explain children's rapid acquisition of linguistic knowledge. Given this, it seems reasonable to examine if children with knowledge of parameters could in fact acquire the adult system from the data available to them.…
ERIC Educational Resources Information Center
Tramontana, G. Michael; Blood, Ingrid M.; Blood, Gordon W.
2013-01-01
The purpose of this study was to determine (a) the general knowledge bases demonstrated by school-based speech-language pathologists (SLPs) in the area of genetics, (b) the confidence levels of SLPs in providing services to children and their families with genetic disorders/syndromes, (c) the attitudes of SLPs regarding genetics and communication…
ERIC Educational Resources Information Center
Beebe, Rosella I.
2012-01-01
This study examined the relationship between human patient simulation (HPS), critical thinking skills, and knowledge acquisition after HPS was integrated across the curriculum of an associate degree nursing program to determine if differences existed in critical thinking and knowledge of students based on the fidelity of HPS used and amount of…
NASA Technical Reports Server (NTRS)
Ligomenides, Panos A.
1989-01-01
A sensory world modeling system, congruent with a human expert's perception, is proposed. The Experiential Knowledge Base (EKB) system can provide a highly intelligible communication interface for telemonitoring and telecontrol of a real time robotic system operating in space. Paradigmatic acquisition of empirical perceptual knowledge, and real time experiential pattern recognition and knowledge integration are reviewed. The cellular architecture and operation of the EKB system are also examined.