Sample records for krista leppik helis

  1. Arnold Hely and Australian Adult Education

    ERIC Educational Resources Information Center

    Morris, Roger


    Arnold Hely (1907-1967) was a most significant figure in the history of adult education in New Zealand, in Australia and internationally. Arnold Hely, a New Zealander, Director of Tutorial Classes (later Adult Education) at the University of Adelaide from 1957 to 1965, was the prime mover in the establishment in 1964 of the Asian South Pacific…

  2. Operation Heli-STAR - Atlanta Communications Experiment (ACE). Volume 9

    NASA Technical Reports Server (NTRS)


    Operation Heli-STAR (Helicopter Short-Haul Transportation and Aviation Research) was established and operated in Atlanta, Georgia, during the period of the 1996 Centennial Olympic Games. Heli-STAR had three major thrusts: (1) the establishment and operation of a helicopter-based cargo transportation system, (2) the management of low-altitude air traffic in the airspace of an urban area, and (3) the collection and analysis of research and development data associated with items 1 and 2. Heli-STAR was a cooperative industry/government program that included parcel package shippers and couriers in the Atlanta area, the helicopter industry, aviation electronics manufacturers, the Federal Aviation Administration (FAA), the National Aeronautics and Space Administration (NASA), and support contractors. Several detailed reports have been produced as a result of Operation Heli-STAR. These include four reports on acoustic measurements and associated analyses, and reports on the Heli-STAR tracking data including the data processing and retrieval system, the Heli-STAR cargo simulation, and the community response system. In addition, NASA's Advanced General Aviation Transport Experiments (AGATE) program has produced a report describing the Atlanta Communications Experiment (ACE) which produced the avionics and ground equipment using automatic dependent surveillance-broadcast (ADS-B) technology. This latter report is restricted to organizations belonging to NASA's AGATE industry consortium. A complete list of these reports is shown on the following page.

  3. 76 FR 16462 - In the Matter of Heli Electronics Corp., Order of Suspension of Trading

    Federal Register 2010, 2011, 2012, 2013, 2014


    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION In the Matter of Heli Electronics Corp., Order of Suspension of Trading March 21, 2011. It appears... concerning the securities of Heli Electronics Corp. (``HELI''), a Nevada corporation with headquarters...

  4. 14 CFR 77.29 - Airport imaginary surfaces for heli-ports.

    Code of Federal Regulations, 2011 CFR


    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Airport imaginary surfaces for heli-ports. 77.29 Section 77.29 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Standards § 77.29 Airport imaginary surfaces for heli-ports. (a) Heliport primary surface. The area of...

  5. HELI-DEM portal for geo-processing services

    NASA Astrophysics Data System (ADS)

    Cannata, Massimiliano; Antonovic, Milan; Molinari, Monia


    HELI-DEM (Helvetia-Italy Digital Elevation Model) is a project developed in the framework of Italy/Switzerland Operational Programme for Trans-frontier Cooperation 2007-2013 whose major aim is to create a unified digital terrain model that includes the alpine and sub-alpine areas between Italy and Switzerland. The partners of the project are: Lombardy Region, Piedmont Region, Polytechnic of Milan, Polytechnic of Turin and Fondazione Politecnico from Italy; Institute of Earth Sciences (SUPSI) from Switzerland. The digital terrain model has been produced by integrating and validating the different elevation data available for the areas of interest, characterized by different reference frame, resolutions and accuracies: DHM at 25 m resolution from Swisstopo, DTM at 20 m resolution from Lombardy Region, DTM at 5 m resolution from Piedmont Region and DTM LiDAR PST-A at about 1 m resolution, that covers the main river bed areas and is produced by the Italian Ministry of the Environment. Further results of the project are: the generation of a unique Italian Swiss geoid with an accuracy of few centimeters (Gilardoni et al. 2012); the establishment of a GNSS permanent network, prototype of a transnational positioning service; the development of a geo-portal, entirely based on open source technologies and open standards, which provides the cross-border DTM and offers some capabilities of analysis and processing through the Internet. With this talk, the authors want to present the main steps of the project with a focus on the HELI-DEM geo-portal development carried out by the Institute of Earth Sciences, which is the access point to the DTM outputted from the project. The portal, accessible at, is a demonstration of open source technologies combined for providing access to geospatial functionalities to wide non GIS expert public. In fact, the system is entirely developed using only Open Standards and Free and Open Source Software (FOSS

  6. Improving proximal fixation and seal with the HeliFx Aortic EndoAnchor.


    Deaton, David H


    Endovascular aneurysm repair (EVAR) transformed the therapy for aortic aneurysms and introduced an era of widespread use for endovascular procedures in a variety of vascular beds. Although dramatic improvements in acute outcomes drove the early enthusiasm for EVAR, a realization that the long-term integrity of the endoprostheses used for EVAR were sometimes inferior to the results obtained with open surgical reconstruction dampened enthusiasm for their use in low-risk and younger patients who mandated long-term follow-up. While early EVAR failure modes are often related to technical aspects of the implantation, late failures are often related to the implant migrating from its original longitudinal position or losing wall apposition in the face of continued aneurysmal dilatation. Migration, or the failure of longitudinal fixation, results in gradual loss of aortic approximation and the eventual repressurization of the aneurysm sac with its attendant risks of growth and rupture. The inability of stent- and barb-based endovascular fixation to resist aortic dilatation at the site of fixation also represents a late failure mode that can result in aneurysm rupture. A variety of endostaples or endoanchors designed to replicate the function of an interrupted aortic suture have been proposed and tested to varying degrees over the years. The device designed and produced by Aptus EndoSystems, now called the HeliFx Aortic EndoAnchor is the only independent endovascular fixation device that has achieved significant clinical usage and Food and Drug Administration approval. The experience with this device is now more than 5 years and it is approved for use in the broad market across both Europe and the United States. This article will review the engineering and design concepts underlying the HeliFx device as well as the in vitro and in vivo results using this device. Finally, a discussion of the potential for technical, procedural, and endograft innovation based on the

  7. Creation of a Multiresolution and Multiaccuracy Dtm: Problems and Solutions for Heli-Dem Case Study

    NASA Astrophysics Data System (ADS)

    Biagi, L.; Carcano, L.; Lucchese, A.; Negretti, M.


    The work is part of "HELI-DEM" (HELvetia-Italy Digital Elevation Model) project, funded by the European Regional Development Fund within the Italy-Switzerland cooperation program. The aim of the project is the creation of a unique DTM for the alpine and subalpine area between Italy (Piedmont, Lombardy) and Switzerland (Ticino and Grisons Cantons); at present, different DTMs, that are in different reference frames and have been obtained with different technologies, accuracies, and resolutions, have been acquired. The final DTM should be correctly georeferenced and produced validating and integrating the data that are available for the project. DTMs are fundamental in hydrogeological studies, especially in alpine areas where hydrogeological risks may exist. Moreover, when an event, like for example a landslide, happens at the border between countries, a unique and integrated DTM which covers the interest area is useful to analyze the scenario. In this sense, HELI-DEM project is helpful. To perform analyses along the borders between countries, transnational geographic information is needed: a transnational DTM can be obtained by merging regional low resolution DTMs. Moreover high resolution local DTMs should be used where they are available. To be merged, low and high resolution DTMs should be in the same three dimensional reference frame, should not present biases and should be consistent in the overlapping areas. Cross-validation between the different DTMs is therefore needed. Two different problems should be solved: the merging of regional, partly overlapping low and medium resolution DTMs into a unique low/medium resolution DTM and the merging with other local high resolution/high accuracy height data. This paper discusses the preliminary processing of the data for the fusion of low and high resolution DTMs in a study-case area within the Lombardy region: Valtellina valley. In this region the Lombardy regional low resolution DTM is available, with a horizontal

  8. Hyperspherical coupled channel calculations of energy and structure of 4He-4He-Li+ and its isotopic combinations

    NASA Astrophysics Data System (ADS)

    Liu, Min-min; Wu, Meng-Shan; Han, Hui-li; Shi, Ting-yun


    The ground state vibrational energy and spatial features of 4He-4He-Li+ and its triatomic isotopic complexes are studied using the slow variable discretization (SVD) method in the hyperspherical coordinates for the zero total angular momentum. Our results show that the dominant structure of the system is an isosceles triangle with the shorter side associated with the two Li+-He distances using the sum-of-potential approximation. Corrections caused by the induced dipole-induced dipole interactions on the He atoms are also investigated. The effects are seen to be small and have a minor influence on the binding energy and the structure of present system. The results are also compared with the full ab initio calculations including all the three-body interactions and information of three-body corrections is obtained.

  9. Hyperspherical coupled channel calculations of energy and structure of (4)He-(4)He-Li(+) and its isotopic combinations.


    Liu, Min-Min; Wu, Meng-Shan; Han, Hui-Li; Shi, Ting-Yun


    The ground state vibrational energy and spatial features of (4)He-(4)He-Li(+) and its triatomic isotopic complexes are studied using the slow variable discretization (SVD) method in the hyperspherical coordinates for the zero total angular momentum. Our results show that the dominant structure of the system is an isosceles triangle with the shorter side associated with the two Li(+)-He distances using the sum-of-potential approximation. Corrections caused by the induced dipole-induced dipole interactions on the He atoms are also investigated. The effects are seen to be small and have a minor influence on the binding energy and the structure of present system. The results are also compared with the full ab initio calculations including all the three-body interactions and information of three-body corrections is obtained. PMID:27448884

  10. Redescription of two subterranean amphipods Niphargus molnari Méhely, 1927 and Niphargus gebhardti Schellenberg, 1934 (Amphipoda, Niphargidae) and their phylogenetic position

    PubMed Central

    Angyal, Dorottya; Balázs, Gergely; Zakšek, Valerija; Krízsik, Virág; Fišer, Cene


    Abstract A detailed redescription of two endemic, cave-dwelling niphargid species of the Hungarian Mecsek Mts., Niphargus molnari Méhely, 1927 and Niphargus gebhardti Schellenberg, 1934 is given based on newly collected material. Morphology was studied under light microscopy and with scanning electon microscopy. Morphological descriptions are complemented with mitochondrial cytochrome c oxidase subunit I (COI) sequences as barcodes for both species and with notes on their ecology. Using three independent molecular markers we showed that Niphargus gebhardti belongs to the clade distributed between Central and Eastern Europe, whereas phylogenetic relationship of Niphargus molnari to the rest of Niphargus species is not clear. The two species from the Mecsek Mts. are phylogenetically not closely related. Both species need to be treated as vulnerable according to IUCN Red List of Threatened Species. PMID:26175603

  11. 14 CFR 77.29 - Airport imaginary surfaces for heli-ports.

    Code of Federal Regulations, 2010 CFR


    ... feet. The slope of the approach surface is 8 to 1 for civil heliports and 10 to 1 for military... boundaries of the heliport primary surface and from the approach surfaces at a slope of 2 to 1 for a...

  12. NIH Abroad: Inspiring the Next Generation of Global Health Researchers


    ... Global Health Researchers Fogarty scholar helps Zambians fight cervical cancer Medical student and Fogarty scholar Krista Pfaendler (right) assists with surgery on a patient with cervical cancer in Zambia. Photo courtesy of Krista Pfaendler An ...

  13. Protonation-induced red-coloured circularly polarized luminescence of [5]carbohelicene fused by benzimidazole.


    Sakai, Hayato; Kubota, Takako; Yuasa, Junpei; Araki, Yasuyuki; Sakanoue, Tomo; Takenobu, Taishi; Wada, Takehiko; Kawai, Tsuyoshi; Hasobe, Taku


    Benzimidazole-fused [5]carbohelicene ([5]HeliBI) was newly synthesized to examine the spectroscopic and chiroptical properties. The reversible protonation and deprotonation processes of [5]HeliBI were successfully investigated using (1)H NMR, absorption and fluorescence spectral measurements. We also confirmed the circularly polarized luminescence of protonated [5]HeliBI (H(+)-[5]HeliBI). This is the first observation of red-coloured CPL of a helicene derivative. PMID:27319321

  14. Examining Teacher Knowledge and Attitudes about School Issues for Children with Epilepsy: A Mixed-Method Investigation

    ERIC Educational Resources Information Center

    Roux, Amy Loomis


    Epilepsy is one of the most common diseases to affect the human nervous system, affecting approximately 0.5% of school-age children (Leppik, 2001; Kaleyias et al., 2005). Epilepsy has the potential to profoundly impact a child's adjustment to school. A large body of literature documents that children with epilepsy are at an increased risk for…

  15. Advanced Control System Increases Helicopter Safety

    NASA Technical Reports Server (NTRS)


    With support and funding from a Phase II NASA SBIR project from Ames Research Center, Hoh Aeronautics Inc. (HAI), of Lomita, California, produced HeliSAS, a low-cost, lightweight, attitude-command-attitude-hold stability augmentation system (SAS) for civil helicopters and unmanned aerial vehicles. HeliSAS proved itself in over 160 hours of flight testing and demonstrations in a Robinson R44 Raven helicopter, a commercial helicopter popular with news broadcasting and police operations. Chelton Flight Systems, of Boise, Idaho, negotiated with HAI to develop, market, and manufacture HeliSAS, now available as the Chelton HeliSAS Digital Helicopter Autopilot.

  16. On Being Watched: Teaching the Wisdom of Adulthood

    ERIC Educational Resources Information Center

    Heischman, Daniel R.


    In "Speaking of Faith," radio journalist Krista Tippett recalls the time when she began to recognize the hypocrisy and contradictions in the behavior of the people around her. Tippett's experience is not only far from unusual, it is formative. It led her to make some important decisions in her life, including the desire never to live a life of…

  17. 76 FR 41602 - Fair Credit Reporting Risk-Based Pricing Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014


    ... ``information overload'' for consumers, and detract from the primary purpose of the credit score information... respective risk-based pricing rules to require disclosure of credit scores and information relating to credit... rules are effective August 15, 2011. FOR FURTHER INFORMATION CONTACT: Board: Krista P. Ayoub,...

  18. Eating Disorders: The Impact on Children and Families. Hearing before the Select Committee on Children, Youth, and Families. House of Representatives, One Hundredth Congress, First Session (San Francisco, CA, July 31, 1987).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Children, Youth, and Families.

    The text of a Congressional hearing to examine the impact of eating disorders on children and families is presented in this document. Testimony by the following witnesses is included: (1) Krista Brown, eating disorder victim, and her mother, Susan Brown; (2) Robert B. Duncan, a hospital president; (3) Patricia Fallon, a clinical psychogist; (4)…

  19. Utopia University: A Faculty Member Reflects on Recommendations for the Future of SoTL

    ERIC Educational Resources Information Center

    Forrest, Krista D.


    The author, Krista D. Forrest, Professor of Psychology, University of Nebraska at Kearney, reports on what it would take to create a "Utopian university," a campus of the future where faculty members' scholarship of teaching and learning (SoTL) has gone on to change departments and as the departments changed, so did the institution.…

  20. IFLA General Conference, 1989. Division of Special Libraries. Section of Administrative Libraries; Section of Social Science Libraries; Section of Geography and Map Libraries; Section of Science and Technology Libraries; Section of Biological and Medical Science Libraries; Section of Art Libraries; Joint Session with the Round Table on Audiovisual Media. The International Association of Law Libraries. Booklet 20.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, The Hague (Netherlands).

    Twenty-one papers from the Division of Special Libraries are included in this collection: "Information Systems Planning as a Tool of Developing Library Work: The Case of Statistics Library" (Heli Myllys); "The Libraries of the French Central Government Departments and the Administrative Library of the City of Paris" (French and English versions;…

  1. Sequential sampling for panicle caterpillars (Lepidoptera: Noctuidae) in sorghum

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Sorghum panicle worm is an economically important insect pest complex of sorghum throughout the Great Plains of the United States, particularly in Texas, Oklahoma, and Kansas. The sorghum panicle worm complex consists of larvae of two highly polyphagous lepidopteran species: the corn earworm, Heli...

  2. Almond of Loretto: Scottish Educational Visionary and Reformer.

    ERIC Educational Resources Information Center

    Mangan, J. A.


    The author details the influence of Hely Hutchinson Almond (1832-1903) on education in Scotland. In 1862 Almond purchased Loretto, a small private school at Musselburgh, where he taught his doctrine of rationality, or sound living, for the next 41 years. (KC)


    EPA Science Inventory

    US EPA currently has H. pylori on its Contaminant Candidate List 2 (CCL 2), methods are needed to detect the occurrence of viable H. pylori in drinking water. H. pyloi is an interesting microorganism because it can change from a cultural and metabolically active state with a heli...

  4. Interpretation of high-resolution low-altitude helicopter magnetometer surveys over sites contaminated with unexploded ordnance

    NASA Astrophysics Data System (ADS)

    Billings, Stephen; Wright, David


    Throughout the world, millions of acres of potentially productive land are contaminated with unexploded ordnance due to either past conflicts or to military training activities. Low-level helicopter magnetometry (HeliMag) is currently being used to rapidly survey large areas and identify regions that are potentially clear of hazardous munitions. One configuration currently in use comprises seven cesium vapor magnetometers, horizontally spaced 1.5 m apart and mounted on a boom several meters in front of a Bell 206L helicopter. Magnetometer data are collected at 400 Hz at altitudes as low as 1.5 m above the ground along transects spaced 7 meters apart. From this dense, high-resolution data, potential metallic targets as small as a 60 mm mortar are identified using manual and/or automatic target picking methods. The target picks are then used to estimate densities of potential contamination. 100% detection is generally not feasible, so that HeliMag is usually applied in a characterization rather than in a clearance mode. We describe a HeliMag survey collected over a UXO contaminated site at Yekau Lake, near Edmonton, Canada. The objective was to identify the location and extent of an 11.5 pound bomb target area at a former training range. The target density estimates derived from manual picks were strongly influenced by geology and clutter and did not reflect the underlying density of ordnance and ordnance related clutter. By fitting a dipole model to each target pick, and comparing it to the expected response of the target item, we could estimate the density of objects with similar size/shape to an 11.5 pound bomb. This analysis clearly identified an area of elevated contamination in the same region where 11.5 pound bombs were found during ground reconnaissance. In summary, the new methodology significantly improves the interpretability of HeliMag data when used for UXO site assessment.

  5. Formation of one-dimensional helical columns and excimerlike excited states by racemic quinoxaline-fused [7]carbohelicenes in the crystal.


    Sakai, Hayato; Shinto, Sho; Araki, Yasuyuki; Wada, Takehiko; Sakanoue, Tomo; Takenobu, Taishi; Hasobe, Taku


    A series of quinoxaline-fused [7]carbohelicenes (HeQu derivatives) was designed and synthesized to evaluate their structural and photophysical properties in the crystal state. The quinoxaline units were expected to enhance the light-emitting properties and to control the packing structures in the crystal. The electrochemical and spectroscopic properties and excited-state dynamics of these compounds were investigated in detail. The first oxidation potentials of HeQu derivatives are approximately the same as that of unsubstituted reference [7]carbohelicene (Heli), whereas their first reduction potentials are shifted to the positive by about 0.7 V. The steady-state absorption, fluorescence, and circular dichroism spectra also became redshifted compared to those of Heli. The molecular orbitals and energy levels of the HOMO and LUMO states, calculated by DFT methods, support these trends. Moreover, the absolute fluorescence quantum yields of HeQu derivatives are about four times larger than that of Heli. The structural properties of the aggregated states were analyzed by single-crystal analysis. Introduction of appropriate substituents (i.e., 4-methoxyphenyl) in the HeQu unit enabled the construction of one-dimensional helical columns of racemic HeQu derivatives in the crystal state. Helix formation is based on intracolumn π-stacking between two neighboring [7]carbohelicenes and intercolumn CH⋅⋅⋅N interaction between a nitrogen atom of a quinoxaline unit and a hydrogen atom of a helicene unit. The time-resolved fluorescence spectra of single crystals clearly showed an excimerlike delocalized excited state owing to the short distance between neighboring [7]carbohelicene units.

  6. Unamplified cap analysis of gene expression on a single-molecule sequencer

    PubMed Central

    Kanamori-Katayama, Mutsumi; Itoh, Masayoshi; Kawaji, Hideya; Lassmann, Timo; Katayama, Shintaro; Kojima, Miki; Bertin, Nicolas; Kaiho, Ai; Ninomiya, Noriko; Daub, Carsten O.; Carninci, Piero; Forrest, Alistair R.R.; Hayashizaki, Yoshihide


    We report the development of a simplified cap analysis of gene expression (CAGE) protocol adapted for single-molecule sequencers that avoids second strand synthesis, ligation, digestion, and PCR. HeliScopeCAGE directly sequences the 3′ end of cap trapped first-strand cDNAs. As with previous versions of CAGE, we better define transcription start sites (TSS) than known models, identify novel regions of transcription and alternative promoters, and find two major classes of TSS signal, sharp peaks and broad regions. However, using this protocol, we observe reproducible evidence of regulation at the much finer level of individual TSS positions. The libraries are quantitative over 5 orders of magnitude and highly reproducible (Pearson's correlation coefficient of 0.987). We have also scaled down the sample requirement to 5 μg of total RNA for a standard HeliScopeCAGE library and 100 ng for a low-quantity version. When the same RNA was run as 5-μg and 100-ng versions, the 100 ng was still able to detect expression for ∼60% of the 13,468 loci detected by a 5-μg library using the same threshold, allowing comparative analysis of even rare cell populations. Testing the protocol for differential gene expression measurements on triplicate HeLa and THP-1 samples, we find that the log fold change compared to Illumina microarray measurements is highly correlated (0.871). In addition, HeliScopeCAGE finds differential expression for thousands more loci including those with probes on the array. Finally, although the majority of tags are 5′ associated, we also observe a low level of signal on exons that is useful for defining gene structures. PMID:21596820

  7. Extracting Hydrogeology from Heliborne Dual Moment Transient Electromagnetic Investigations in Geologically Divergent Terrenes

    NASA Astrophysics Data System (ADS)

    Ahmed, S.; Chandra, S.; Auken, E.; Verma, S. K.


    Comprehensive knowledge of aquifer system is an important requisite for its effective management in India. Geological formations are complex and variable, punctual and scarce information are not adequate to understand, asses and manage them. Continuous data acquisition, their interpretation and integration with available geological/geophysical information is the solution. Heliborne dual moment transient electromagnetic (HeliTEM) and magnetic (HeliMAG) measurements have been carried out in divergent geological terrenes in India comprising Gangetic alluvium, Tertiary sediments underlying the Thar desert, Deccan basalts and Gondwana sediments, weathered and fractured granite gneisses and schists and the coastal alluvium with Tertiary sediments. The survey was carried out using state of the art equipment SkyTEM. The paper presents a synopsis of the results of the HeliTEM surveys that have helped in obtaining continuous information on the geoelectrical nature of sub-surface. HeliTEM data were supported by a number of ground geophysical surveys. The results provide the 3D subsurface structures controlling the groundwater conditions, the regional continuity of probable aquifers, the variations in lithological character and the quality of water in terms of salinity. Specialized features pertaining to hydrogeological characteristics obtained from this study are as follows: A clear delineation of clay beds and their spatial distribution providing the multi-layered aquifer setup in the Gangetic plains. Delineation of low resistivity zones in the quartzite below the over exploited aquifers indicating the possibility of new aquifers. Presence of freshwater zones underneath the saline water aquifers in the thick and dry sands in deserts. Clear demarcation of different lava flows, mapping the structural controls and highly porous zones in the contact of basalts and Gondwanas. A complete and continuous mapping of weathered zone in crystalline hard rock areas providing information



    Noland, R.A.; Stone, C.C.


    A method is presented for joining sections of uranium rod which are clad in a corrosion-resistant material of higher melting point than uranium. The method includes the steps of preferentially- etching the uranium in the ends of the sections to be joined to depress the level of the uranium slighily below that of the cladding, bringing the ends to be joined together, applying axial pressure to the joint, and heli-arc welding the joint while rotating the joint, to fuse the cladding to a uniform depth of about 50% of the thickness of the cladding.

  9. Extracting Hydrogeology from Heliborne Dual Moment Transient Electromagnetic Investigation in Geologically Divergent Terrenes

    NASA Astrophysics Data System (ADS)

    Ahmed, S.; Chandra, S.; Auken, E.; Verma, S. K.


    Comprehensive knowledge of aquifer system is an important requisite for its effective management in India. Geological formations are complex and variable, punctual and scarce information are not adequate to understand, asses and manage them. Continuous data acquisition, their interpretation and integration with available geological/geophysical information is the solution. Heliborne dual moment transient electromagnetic (HeliTEM) and magnetic (HeliMAG) measurements have been carried out in divergent geological terrenes in India comprising Gangetic alluvium, Tertiary sediments underlying the Thar desert, Deccan basalts and Gondwana sediments, weathered and fractured granite gneisses and schists and the coastal alluvium with Tertiary sediments. The survey was carried out using state of the art equipment SkyTEM. The paper presents a synopsis of the results of the HeliTEM surveys that have helped in obtaining continuous information on the geoelectrical nature of sub-surface. HeliTEM data were supported by a number of ground geophysical surveys. The results provide the 3D subsurface structures controlling the groundwater conditions, the regional continuity of probable aquifers, the variations in lithological character and the quality of water in terms of salinity. Specialized features pertaining to hydrogeological characteristics obtained from this study are as follows:  A clear delineation of clay beds and their spatial distribution providing the multi-layered aquifer setup in the Gangetic plains.  Delineation of low resistivity zones in the quartzite below the over exploited aquifers indicating the possibility of new aquifers.  Presence of freshwater zones underneath the saline water aquifers in the thick and dry sands in deserts.  Clear demarcation of different lava flows, mapping the structural controls and highly porous zones in the contact of basalts and Gondwanas.  A complete and continuous mapping of weathered zone in crystalline hard rock areas

  10. Automated Workflow for Preparation of cDNA for Cap Analysis of Gene Expression on a Single Molecule Sequencer

    PubMed Central

    Nagao-Sato, Sayaka; Saijo, Eri; Lassmann, Timo; Kanamori-Katayama, Mutsumi; Kaiho, Ai; Lizio, Marina; Kawaji, Hideya; Carninci, Piero; Forrest, Alistair R. R.; Hayashizaki, Yoshihide


    Background Cap analysis of gene expression (CAGE) is a 5′ sequence tag technology to globally determine transcriptional starting sites in the genome and their expression levels and has most recently been adapted to the HeliScope single molecule sequencer. Despite significant simplifications in the CAGE protocol, it has until now been a labour intensive protocol. Methodology In this study we set out to adapt the protocol to a robotic workflow, which would increase throughput and reduce handling. The automated CAGE cDNA preparation system we present here can prepare 96 ‘HeliScope ready’ CAGE cDNA libraries in 8 days, as opposed to 6 weeks by a manual operator.We compare the results obtained using the same RNA in manual libraries and across multiple automation batches to assess reproducibility. Conclusions We show that the sequencing was highly reproducible and comparable to manual libraries with an 8 fold increase in productivity. The automated CAGE cDNA preparation system can prepare 96 CAGE sequencing samples simultaneously. Finally we discuss how the system could be used for CAGE on Illumina/SOLiD platforms, RNA-seq and full-length cDNA generation. PMID:22303458

  11. Stratospheric platforms: a novel technological support for Earth observation and remote sensing applications

    NASA Astrophysics Data System (ADS)

    Dovis, Fabio; Lo Presti, Letizia; Magli, Enrico; Mulassano, Paolo; Olmo, Gabriella


    The international community agrees that the new technology based on the use of Unmanned Air Vehicles High Altitude Very long Endurance (UAV-HAVE) could play an important role for the development of remote sensing and telecommunication applications. A UAV-HAVE vehicle can be described as a low- cost flying infrastructure (compared with satellites) optimized for long endurance operations at an altitude of about 20 km. Due to such features, its role is similar to satellites, with the major advantages of being less expensive, more flexible, movable on demand, and suitable for a larger class of applications. According to this background, Politecnico di Torino is involved as coordinator in an important project named HeliNet, that represent one of the main activities in Europe in the field of stratospheric platforms, and is concerned with the development of a network of UAV-HAVE aircraft. A key point of this project is the feasibility study for the provision of several services, namely traffic monitoring, environmental surveillance, broadband communications and navigation. This paper reports preliminary results on the HeliNet imaging system and its remote sensing applications. In fact, many environmental surveillance services (e.g. regional public services for agriculture, hydrology, fire protection, and more) require very high-resolution imaging, and can be offered at a lower cost if operated by a shared platform. The philosophy behind the HeliNet project seems to be particularly suitable to manage such missions. In particular, we present a system- level study of possible imaging payloads to be mounted on- board of a stratospheric platform to collect Earth observation data. Firstly, we address optical payloads such as multispectral and/or hyperspectral ones, which are a very short-term objective of the project. Secondly, as an example of mid-term on-board payload, we examine the possibility to carry on the platform a light-SAR system. For both types of payload, we show


    SciTech Connect



    As part of the 200-PO-1 Phase I geophysical surveys, Fugro Airborne Surveys was contracted to collect airborne electromagnetic (EM) and magnetic surveys of the Hanford Site 600 Area. Two helicopter survey systems were used with the HeliGEOTEM{reg_sign} time domain portion flown between June 19th and June 20th, 2008, and the RESOLVE{reg_sign} frequency domain portion was flown from June 29th to July 1st, 2008. Magnetic data were acquired contemporaneously with the electromagnetic surveys using a total-field cesium vapor magnetometer. Approximately 925 line kilometers (km) were flown using the HeliGEOTEM{reg_sign} II system and 412 line kilometers were flown using the RESOLVE{reg_sign} system. The HeliGEOTEM system has an effective penetration of roughly 250 meters into the ground and the RESOLVE system has an effective penetration of roughly 60 meters. Acquisition parameters and preliminary results are provided in SGW-39674, Airborne Electromagnetic Survey Report, 200-PO-1 Groundwater Operable Unit, 600 Area, Hanford Site. Airborne data are interpreted in this report in an attempt to identify areas of likely preferential groundwater flow within the aquifer system based on the presence of paleochannels or fault zones. The premise for the interpretation is that coarser-grained intervals have filled in scour channels created by episodic catastrophic flood events during the late Pleistocene. The interpretation strategy used the magnetic field anomaly data and existing bedrock maps to identify likely fault or lineament zones. Combined analysis of the magnetic, 60-Hz noise monitor, and flight-altitude (radar) data were used to identify zones where EM response is more likely due to cultural interference and or bedrock structures. Cross-sectional and map view presentations of the EM data were used to identify more electrically resistive zones that likely correlate with coarser-grained intervals. The resulting interpretation identifies one major northwest-southeast trending

  13. From golden hills to sycamore trees: pastoral homelands and ethnic identity in Irish immigrant fiction, 1860-75.


    Corporaal, Marguérite


    The prose fiction that remembers the trials of starvation and eviction of the Great Famine (1845-50) often juxtaposes representations of blasted, infertile land with images of a green, idyllic Erin. Through a discussion of Mary Anne Sadlier's Bessy Conway (1861), Elizabeth Hely Walshe's Golden Hills: A Tale of the Irish Famine (1865) and John McElgun's Annie Reilly (1873), this article reveals that immigrant writers of the Famine generation often negotiate depictions of Famine-stricken wasteland with evocations of a pastoral homeland. In the case of the two Catholic novels, Bessy Conway and Annie Reilly, the pastoral becomes a point of ethnic identification through which the immigrants can recollect and reconstruct a sense of Irishness in exile. By contrast, Golden Hills, which focuses on the Anglo-Irish ascendancy, does not lament the mass exodus of afflicted Irish: the novel rather envisions emigration as a way to regenerate Ireland as locus amoenus.

  14. The peculiar N- and (-termini of trichogin GA IV are needed for membrane interaction and human cell death induction at doses lacking antibiotic activity.


    Tavano, Regina; Malachin, Giulia; De Zotti, Marta; Peggion, Cristina; Biondi, Barbara; Forrnaggio, Fernando; Papini, Emanuele


    Peptaibiotics, non-ribosomally synthetized peptides from various ascomycetes, are uniquely characterized by dialkylated a-amino acids, a rigid heli cal conformation, and membrane permeation properties. Although generally considered as antimicrobial peptides, peptaibiotics may display other toxicological properties, and their function is in many cases unknown. With the goal to define the biological activity and selectivity of the peptaibiotictrichogin GA IV from the human opportunist Trichodenna longibrachiatum we analyzed its membrane interaction,cytotoxic activity and antibacterial effect. Trichogin GA IV effectively killed several types of healthy and neoplastic human cells at doses (EC 50%= 4-6 ~) lacking antibiotic effects on both Gram- and Gram+ bacteria(MIC > 64 ~ ). The peptaibiotic distinctive (-terminal primary alcohol was found to cooperate with theN-terminal n-octanoyl group to permeate the membrane phospholipid bilayer and to mediate effective binding and active endocytosis of trichogin GA IV in eukaryotic cells, two steps essential for cell death induction.Replacement of one Gly with Lys plus the simultaneous esterification of the (-terminus, strongly increased trichogin GA IV anti-Gram+ activity (MIC 1-4 ~ ). but further mitigated its cytotoxicity on human cells. PMID:25306964

  15. Variable flow -- the quest for system energy efficiency

    SciTech Connect

    Eppelheimer, D.M.


    Varying condenser water flow has long been used as a method of controlling head pressure in water-cooled refrigeration systems. This method of head pressure control has been applied successfully on systems with scroll, reciprocating, heli-rotor, and centrifugal compressors. Condenser water flow is altered either by bypassing the condenser via a three-way valve or by throttling flow with a two-way valve. Today, the affordability and potential energy savings of adjustable speed drives makes this the preferred method of varying flow. In the quest for greater energy savings, many designers propose to vary the flow of water through the evaporators of chillers also. This feat is not as easily accomplished as the first. There are system designs that allow variable flow of chilled water at the system level while maintaining constant flow through the chiller evaporator. Yet in spite of the risk and the presence of other variable options, some still wish to vary the flow of chilled water through the evaporator by large proportions. Can it be done? Of course! However, there are a few engineering problems that must be tackled to accomplish this feat. This paper delineates those problems.

  16. Changes in default mode network as automaticity develops in a categorization task.


    Shamloo, Farzin; Helie, Sebastien


    The default mode network (DMN) is a set of brain regions in which blood oxygen level dependent signal is suppressed during attentional focus on the external environment. Because automatic task processing requires less attention, development of automaticity in a rule-based categorization task may result in less deactivation and altered functional connectivity of the DMN when compared to the initial learning stage. We tested this hypothesis by re-analyzing functional magnetic resonance imaging data of participants trained in rule-based categorization for over 10,000 trials (Helie et al., 2010) [12,13]. The results show that some DMN regions are deactivated in initial training but not after automaticity has developed. There is also a significant decrease in DMN deactivation after extensive practice. Seed-based functional connectivity analyses with the precuneus, medial prefrontal cortex (two important DMN regions) and Brodmann area 6 (an important region in automatic categorization) were also performed. The results show increased functional connectivity with both DMN and non-DMN regions after the development of automaticity, and a decrease in functional connectivity between the medial prefrontal cortex and ventromedial orbitofrontal cortex. Together, these results further support the hypothesis of a strategy shift in automatic categorization and bridge the cognitive and neuroscientific conceptions of automaticity in showing that the reduced need for cognitive resources in automatic processing is accompanied by a disinhibition of the DMN and stronger functional connectivity between DMN and task-related brain regions. PMID:27457134

  17. High energy density capacitors for vacuum operation with a pulsed plasma load

    NASA Technical Reports Server (NTRS)

    Guman, W. J.


    Results of the effort of designing, fabricating, and testing of a 40 joules/lb (88.2 joules/Kg) high voltage energy storage capacitor suitable for operating a pulsed plasma thruster in a vacuum environment for millions of pulses are presented. Using vacuum brazing and heli-arc welding techniques followed by vacuum and high pressure helium leak tests it was possible to produce a hermetically sealed relatively light weight enclosure for the dielectric system. An energy density of 40 joules/lb was realized with a KF-polyvinylidene fluoride dielectric system. One capacitor was D.C. life tested at 4 KV (107.8 joules/lb) for 2,000 hours before it failed. Another exceeded 2,670 hours without failure at 38.3 joules/lb. Pulse life testing in a vacuum exceeded 300,000 discharges with testing still in progress. The D.C. life test data shows a small decrease in capacitance and an increase in dissipation factor with time. Heat transfer from the load to the capacitor must also be considered besides the self-heat generated by the capacitor.

  18. Answering geological questions from slimhole coring exploration

    SciTech Connect

    Jantzen, R.E.; Syrstad, S.O.; Stockden, I.; Taylor, M. )


    Slimhole exploration wells have been proposed as a cost-efficient method of exploring inaccessible and remote areas. Such areas often have limited geological control, and the use of wire-line-retrieved, continuous coring methods adapted from the solid minerals industry can greatly improve the geological knowledge of a prospect or basin. However, there are geological concerns which may hinder the spread of slimhole exploration. The availability of core from long continuous sections of the well required a rethink of geological knowledge acquisition at the wellsite. Market analysis among explorationists confirmed the critical answers required from the core before it leaves the wellsite. These include the presence or absence of hydrocarbons, reservoirs, seals, source rock and maturity, lithologies and depositional environments. To provide answers, a conceptual core screening operation was developed around key variables which answer these geological questions. Throughput analyses, followed by time and motion studies, were performed to ensure wellsite suitability. A series of analysis systems have been built and assembled into a fit-for-purpose, heli-transportable wellsite core logging facility which has successfully completed a four well field trial in Africa. The purpose of this facility is to digitally preserve these key variables from the core through the use of a fully integrated data set encompassing mud, core and wireline logs, together with high-resolution digital images of the core. Data transmission from the wellsite to the project explorationists will ensure rapid answers from a cost-effective novel exploration method.

  19. A reappraisal of the controversy of Dax and Broca.


    Cubelli, R; Montagna, C G


    Paul Broca is unanimously recognized as the founder of neuropsychology. Helis development of the scientific method to map mental functions onto brain topographpy has been enormously influential. Nevertheless, Dax's paper on the left hemisphere dominance for speech was written and published before Broca explicitely proposed the same theory. Probably, Broca was aware of the paper prior to 1865, but he never acknowledged Dax's original theoretical contribution. On the contrary, he always claimed to be the first to espouse the theory of left hemisphere dominance for language and never quoted Marc Dax (Broca, 1877 p 536), 'I do not like dealing with the questions of priority concerning myself. That is the reason why I did not mention the name of Dax in my paper'. In our opinion, the weight of evidence reported here suggests that the theory of the left hemisphere dominance for speech must be attributed equally to Dax and Broca, and henceforth should be called 'the theory of Dax-Broca'. PMID:11618822

  20. Formation processes of floe size distribution in the marginal ice zone (Invited)

    NASA Astrophysics Data System (ADS)

    Toyota, T.; Kohout, A.; Fraser, A.


    Since the marginal ice zone (MIZ) is the outer sea ice zone, its behavior is key to the understanding of the variability of sea ice extent associated with climate change. Especially for the melting processes in MIZ, where relatively small ice floes are dominant, floe size distribution (FSD) is an important parameter because smaller ice floes are subject to stronger lateral melting due to their larger cumulative perimeters. As the MIZ is characterized by vigorous interaction between sea ice and waves, breakup of sea ice due to flexural forcing and collisions is considered to play an essential role in the determination of FSD there. However, the available data have been very limited so far. Analysis of the observations of ice floes with a heli-borne video camera, focusing on the floe size ranging from 2 m to 100 m, in the Sea of Okhotsk, the Weddell Sea and off East Antarctica, revealed that while FSD is basically scale-invariant, a regime shift occurs at a size of about a few tens of meters, irrespective of the study region. It was also shown 1) that the floe size at which regime shift occurs slightly increases from 20 to 40 m with ice thickness, consistent with the theory of the flexural failure of sea ice; and 2) that to explain the scale invariance in FSD for smaller floes, a fragility of sea ice which is relevant to the strength of sea ice relative to waves can be a useful physical parameter to be correlated with the fractal dimension. Thus these results confirm the importance of wave-ice interaction to the formation of FSD. Based on this, a possible mechanism of the melting process was hypothesized that in the melting season sea ice extent retreats keeping the FSD relative to the ice edge nearly constant. As a next step and to confirm and further investigate this result, we planned to conduct the concurrent measurements of FSD, wave activities, and ice thickness off East Antarctica during the Sea Ice Physics and Ecosystem Experiment 2 (SIPEX2) in September to

  1. Answering geological questions from slim-hole coring exploration

    SciTech Connect

    Jantzen, R.E.; Stockden, I. ); Syrstad, S.O. ); Taylor, M.R. ); Saunders, M.R. , Windsor )


    Slim-hole exploration wells have been proposed as a cost-effective method of exploring inaccessible and remote areas. These areas often have limited geological control, and the use of wireline-retrieved, continuous coring methods adapted from the mining industry can greatly improve the geological knowledge of a prospect or basin. The availability of core from long continuous sections of the well requires a rethink of geological knowledge acquisition performed at the well site. Market analysis among today's explorationists highlighted the critical answers required from the core before it leave the location. These include the presence or absence of hydrocarbons, reservoirs, seals, source rock and maturity, lithologies, and depositional environments. To provide these answers, a conceptual core screening operation was developed around key variables that answer the geological questions. Throughout, analyses, followed by time and motion studies, were performed to ensure well-site suitability. A series of analysis systems have been built and assembled into a fit-for-purpose, heli-transportable well-site core logging facility, which successfully completed a four-well field trial in Africa during 1992. The purpose of the facility is to digitally preserve the key variables from the core. Core measurements made include natural gamma ray, density/porosity, caliper, permeability, total organic carbon, and Rock-Eval pyrolysis, together with high-resolution white light and U.V. digital images. A geological workstation allows for speed, geologically-correct descriptions, preserving all geological data in digital form. Through the use of a fully integrated data set, encompassing mud, geological, core, and wireline logs, the key variable are combined and plotted to provide near-real-time composite logs for the geologist and petrophysicist. Data transmission from the well site to the project explorationists ensure rapid answers from a cost-effective, novel exploration method.

  2. True single-molecule DNA sequencing of a pleistocene horse bone

    PubMed Central

    Orlando, Ludovic; Ginolhac, Aurelien; Raghavan, Maanasa; Vilstrup, Julia; Rasmussen, Morten; Magnussen, Kim; Steinmann, Kathleen E.; Kapranov, Philipp; Thompson, John F.; Zazula, Grant; Froese, Duane; Moltke, Ida; Shapiro, Beth; Hofreiter, Michael; Al-Rasheid, Khaled A.S.; Gilbert, M. Thomas P.; Willerslev, Eske


    Second-generation sequencing platforms have revolutionized the field of ancient DNA, opening access to complete genomes of past individuals and extinct species. However, these platforms are dependent on library construction and amplification steps that may result in sequences that do not reflect the original DNA template composition. This is particularly true for ancient DNA, where templates have undergone extensive damage post-mortem. Here, we report the results of the first “true single molecule sequencing” of ancient DNA. We generated 115.9 Mb and 76.9 Mb of DNA sequences from a permafrost-preserved Pleistocene horse bone using the Helicos HeliScope and Illumina GAIIx platforms, respectively. We find that the percentage of endogenous DNA sequences derived from the horse is higher among the Helicos data than Illumina data. This result indicates that the molecular biology tools used to generate sequencing libraries of ancient DNA molecules, as required for second-generation sequencing, introduce biases into the data that reduce the efficiency of the sequencing process and limit our ability to fully explore the molecular complexity of ancient DNA extracts. We demonstrate that simple modifications to the standard Helicos DNA template preparation protocol further increase the proportion of horse DNA for this sample by threefold. Comparison of Helicos-specific biases and sequence errors in modern DNA with those in ancient DNA also reveals extensive cytosine deamination damage at the 3′ ends of ancient templates, indicating the presence of 3′-sequence overhangs. Our results suggest that paleogenomes could be sequenced in an unprecedented manner by combining current second- and third-generation sequencing approaches. PMID:21803858

  3. Environmental Public Health Surveillance for Exposure to Respiratory Health Hazards: A Joint NASA/CDC Project to Use Remote Sensing Data for Estimating Airborne Particulate Matter Over the Atlanta, Georgia Metropolitan Area

    NASA Technical Reports Server (NTRS)

    Quattrochi, Dale A.; Al-Hamdan, Mohammad; Estes, Maurice; Crosson, William


    As part of the National Environmental Public Health Tracking Network (EPHTN) the National Center for Environmental Health (NCEH) at the Centers for Disease Control and Prevention (CDC) is leading a project called Health and Environment Linked for Information Exchange (HELiX-Atlanta). The goal of developing the National Environmental Public Health Tracking Network is to improve the health of communities. Currently, few systems exist at the state or national level to concurrently track many of the exposures and health effects that might be associated with environmental hazards. An additional challenge is estimating exposure to environmental hazards such as particulate matter whose aerodynamic diameter is less than or equal to 2.5 micrometers (PM2.5). HELIX-Atlanta's goal is to examine the feasibility of building an integrated electronic health and environmental data network in five counties of Metropolitan Atlanta, GA. NASA Marshall Space Flight Center (NASA/MSFC) is collaborating with CDC to combine NASA earth science satellite observations related to air quality and environmental monitoring data to model surface estimates of PM2.5 concentrations that can be linked with clinic visits for asthma. While use of the Air Quality System (AQS) PM2.5 data alone could meet HELIX-Atlanta specifications, there are only five AQS sites in the Atlanta area, thus the spatial coverage is not ideal. We are using NASA Moderate Resolution Imaging Spectroradiometer (MODIS) satellite Aerosol Optical Depth (AOD) data for estimating daily ground level PM2.5 at 10 km resolution over the metropolitan Atlanta area supplementing the AQS ground observations and filling their spatial and temporal gaps.

  4. Formation processes of sea ice floe size distribution in the interior pack and its relationship to the marginal ice zone off East Antarctica

    NASA Astrophysics Data System (ADS)

    Toyota, Takenobu; Kohout, Alison; Fraser, Alexander D.


    To understand the behavior of the Seasonal Ice Zone (SIZ), which is composed of sea-ice floes of various sizes, knowledge of the floe size distribution (FSD) is important. In particular, FSD in the Marginal Ice Zone (MIZ), controlled by wave-ice interaction, plays an important role in determining the retreating rates of sea-ice extent on a global scale because the cumulative perimeter of floes enhances melting. To improve the understanding of wave-ice interaction and subsequent effects on FSD in the MIZ, FSD measurements were conducted off East Antarctica during the second Sea Ice Physics and Ecosystems eXperiment (SIPEX-2) in late winter 2012. Since logistical reasons limited helicopter operations to two interior ice regions, FSD in the interior ice region was determined using a combination of heli-photos and MODIS satellite visible images. The possible effect of wave-ice interaction in the MIZ was examined by comparison with past results obtained in the same MIZ, with our analysis showing: (1) FSD in the interior ice region is basically scale invariant for both small- (<100 m) and large- (>1 km) scale regimes; (2) although fractal dimensions are quite different between these two regimes, they are both rather close to that in the MIZ; and (3) for floes <100 m in diameter, a regime shift which appeared at 20-40 m in the MIZ is absent. These results indicate that one role of wave-ice interaction is to modulate the FSD that already exists in the interior ice region, rather than directly determine it. The possibilities of floe-floe collisions and storm-induced lead formation are considered as possible formation processes of FSD in the interior pack.


    SciTech Connect



    Airborne electromagnetic (AEM) surveys were flown during fiscal year (FY) 2008 within the 600 Area in an attempt to characterize the underlying subsurface and to aid in the closure and remediation design study goals for the 200-PO-1 Groundwater Operable Unit (OU). The rationale for using the AEM surveys was that airborne surveys can cover large areas rapidly at relatively low costs with minimal cultural impact, and observed geo-electrical anomalies could be correlated with important subsurface geologic and hydrogeologic features. Initial interpretation of the AEM surveys indicated a tenuous correlation with the underlying geology, from which several anomalous zones likely associated with channels/erosional features incised into the Ringold units were identified near the River Corridor. Preliminary modeling resulted in a slightly improved correlation but revealed that more information was required to constrain the modeling (SGW-39674, Airborne Electromagnetic Survey Report, 200-PO-1 Groundwater Operable Unit, 600 Area, Hanford Site). Both time-and frequency domain AEM surveys were collected with the densest coverage occurring adjacent to the Columbia River Corridor. Time domain surveys targeted deeper subsurface features (e.g., top-of-basalt) and were acquired using the HeliGEOTEM{reg_sign} system along north-south flight lines with a nominal 400 m (1,312 ft) spacing. The frequency domain RESOLVE system acquired electromagnetic (EM) data along tighter spaced (100 m [328 ft] and 200 m [656 ft]) north-south profiles in the eastern fifth of the 200-PO-1 Groundwater OU (immediately adjacent to the River Corridor). The overall goal of this study is to provide further quantification of the AEM survey results, using ground based geophysical methods, and to link results to the underlying geology and/or hydrogeology. Specific goals of this project are as follows: (1) Test ground based geophysical techniques for the efficacy in delineating underlying geology; (2) Use ground

  6. HD gas purification for polarized HDice targets production at Jefferson Lab

    SciTech Connect

    Whisnant, Charles; D'Angelo, Annalisa; Colaneri, Luca; Devilbiss, J; Kageya, Tsuneo; Loving, D A; Lowry, Michael; Rizzo, Alessandro; Sandorfi, Andrew; Schaerf, Carlo; Storey, J D; Wallace, C M; Wei, Xiangdong; Zonta, Irene


    Solid, frozen-spin targets of molecular HD were rst developed for nuclear physics by a collaboration between Syracuse University and Brookhaven National Lab. They have been successfully used in measurements with photon beams, rst at the Laser-Electron-Gamma-Source [1] and most recently at Je erson Lab during the running of the E06-101 (g14) experiment [2]. Preparations are underway to utilize the targets in future electron experiments after the completion of the 12 GeV JLab upgrade [3]. HD is an attractive target since all of the material is polarizable, of low Z, and requires only modest holding elds. At the same time, the small contributions from the target cell can be subtracted from direct measurements. Reaching the frozen-spin state with both high polarization and a signi cant spin relaxation time requires careful control of H2 and D2 impurities. Commercially available HD contains 0.5 - 2% concentrations of H2 and D2. Low-temperature distillation is required to reduce these concentrations to the 104 level to enable useful target production. This distillation is done using a column lled with heli-pack C [4] to give good separation e ciency. Approximately 12 moles of commercial HD is condensed into the mechanically refrigerated system at the base temperature of 11K. The system is then isolated and the temperature stabilized at 18K producing liquid HD, which is boiled by a resistive heater. The circulation established by the boil-o condensing throughout the column then ltering back down produces a steady-state isotopic separation permitting the extraction of HD gas with very low H2 and D2 content. A residual gas analyzer initially monitors distillation. Once the H2 concentration falls below its useful operating range, samples are periodically collected for analysis using gas chromatography [5] and Raman scattering. Where the measurement techniques overlap, good agreement is obtained. The operation of the distillery and results of gas analysis will be discussed

  7. DTMs: discussion of a new multi-resolution function based model

    NASA Astrophysics Data System (ADS)

    Brovelli, M. A.; Biagi, L.; Zamboni, G.


    transmitted to the clients. These data allow the complete reconstruction of the terrain at any point. A preliminary implementation of the algorithm had been already presented: however, some optimization problems were present in the automatic choice of the activated splines. Now, all these problems have been solved and the algorithm has been completely implemented. In the presentation, the new multi-resolution approach is discussed and compared with the traditional techniques to interpolate, store and transmit DTMs, considering accuracy and storage requirements. Moreover it is compared with other multi-resolution techniques. Different case studies of smooth and rough terrains have been analyzed: the results provided by our approach are completely satisfactory. The research has been funded by the INTERREG HELI-DEM (Helvetia Italy Digital Elevation Model) project.

  8. Blind Geothermal System Exploration in Active Volcanic Environments; Multi-phase Geophysical and Geochemical Surveys in Overt and Subtle Volcanic Systems, Hawai’i and Maui

    SciTech Connect

    Fercho, Steven; Owens, Lara; Walsh, Patrick; Drakos, Peter; Martini, Brigette; Lewicki, Jennifer L.; Kennedy, Burton M.


    Suites of new geophysical and geochemical exploration surveys were conducted to provide evidence for geothermal resource at the Haleakala Southwest Rift Zone (HSWRZ) on Maui Island, Hawai’i. Ground-based gravity (~400 stations) coupled with heli-bourne magnetics (~1500 line kilometers) define both deep and shallow fractures/faults, while also delineating potentially widespread subsurface hydrothermal alteration on the lower flanks (below approximately 1800 feet a.s.l.). Multi-level, upward continuation calculations and 2-D gravity and magnetic modeling provide information on source depths, but lack of lithologic information leaves ambiguity in the estimates. Additionally, several well-defined gravity lows (possibly vent zones) lie coincident with magnetic highs suggesting the presence of dike intrusions at depth which may represent a potentially young source of heat. Soil CO2 fluxes were measured along transects across geophysically-defined faults and fractures as well as young cinder cones along the HSWRZ. This survey generally did not detect CO2 levels above background, with the exception of a weak anomalous flux signal over one young cinder cone. The general lack of observed CO2 flux signals on the HSWRZ is likely due to a combination of lower magmatic CO2 fluxes and relatively high biogenic surface CO2 fluxes which mix with the magmatic signal. Similar surveys at the Puna geothermal field on the Kilauea Lower East Rift Zone (KLERZ) also showed a lack of surface CO2 flux signals, however aqueous geochemistry indicated contribution of magmatic CO2 and He to shallow groundwater here. As magma has been intercepted in geothermal drilling at the Puna field, the lack of measured surface CO2 flux indicative of upflow of magmatic fluids here is likely due to effective “scrubbing” by high groundwater and a mature hydrothermal system. Dissolved inorganic carbon (DIC) concentrations, δ13C compositions and 3He/4He values were sampled at Maui from several shallow

  9. Airborne imaging for heritage documentation using the Fotokite tethered flying camera

    NASA Astrophysics Data System (ADS)

    Verhoeven, Geert; Lupashin, Sergei; Briese, Christian; Doneus, Michael


    Since the beginning of aerial photography, researchers used all kinds of devices (from pigeons, kites, poles, and balloons to rockets) to take still cameras aloft and remotely gather aerial imagery. To date, many of these unmanned devices are still used for what has been referred to as Low-Altitude Aerial Photography or LAAP. In addition to these more traditional camera platforms, radio-controlled (multi-)copter platforms have recently added a new aspect to LAAP. Although model airplanes have been around for several decades, the decreasing cost, increasing functionality and stability of ready-to-fly multi-copter systems has proliferated their use among non-hobbyists. As such, they became a very popular tool for aerial imaging. The overwhelming amount of currently available brands and types (heli-, dual-, tri-, quad-, hexa-, octo-, dodeca-, deca-hexa and deca-octocopters), together with the wide variety of navigation options (e.g. altitude and position hold, waypoint flight) and camera mounts indicate that these platforms are here to stay for some time. Given the multitude of still camera types and the image quality they are currently capable of, endless combinations of low- and high-cost LAAP solutions are available. In addition, LAAP allows for the exploitation of new imaging techniques, as it is often only a matter of lifting the appropriate device (e.g. video cameras, thermal frame imagers, hyperspectral line sensors). Archaeologists were among the first to adopt this technology, as it provided them with a means to easily acquire essential data from a unique point of view, whether for simple illustration purposes of standing historic structures or to compute three-dimensional (3D) models and orthophotographs from excavation areas. However, even very cheap multi-copters models require certain skills to pilot them safely. Additionally, malfunction or overconfidence might lift these devices to altitudes where they can interfere with manned aircrafts. As such, the

  10. [Pliability and deflection of diagnostic catheters].


    Pelyhe, Liza; Bognár, Eszter


    Bevezetés: A szívkatéter olyan intravascularis katéter, amelyet a szívbe vezetnek vagy ültetnek be diagnosztikus vagy terápiás célból. A katéterek felvezetés/eltávolítás közben megtörhetnek vagy eltörhetnek. Célkitűzés: A szerzők két azonos alapanyagú, de különböző átmérőjű katéter hajlékonyságának meghatározását tűzték ki célul a Food and Drug Administration ajánlása alapján. Módszer: Meghatározták a hajlítási pontokat, a pontokon az átmérőcsökkenést, az elhajlás változását, továbbá e két paraméter csúcstól mért távolságának függését, korrelációjukat és a katéter kezdeti átmérőjének hatását. A katétereket 9-9 ponton (120–280 mm-re a páciensbe bevezetett végtől 20 mm-ként), 16 különböző sugarú idomszeren hajlították meg, amelyek sugara 10 mm-től 2,5 mm-ig 0,5 mm-ként csökkent. Eredmények: Megállapították, hogy az átmérőcsökkenés és az elhajlás lineárisan korrelál egymással, és függetlenek a mérési pont helyétől mindkét katéter esetében. A nagyobb átmérőjű katéternél szignifikánsan (p = 0,05) nagyobb volt az átmérőcsökkenés, mint a kisebbnél, de az átmérőcsökkenés és az elhajlási görbék lefutása hasonló. Következtetések: Az alkalmazott módszer alkalmasnak tűnik az adott típusú katéterek lehetséges gyenge pontjainak vizsgálatára. Orv. Hetil., 2014, 155(39), 1544–1548.

  11. Modelo de atmosfera solar ajustado às observações do raio solar em 17GHz

    NASA Astrophysics Data System (ADS)

    Selhorst, C. L.; Silva, A. V. R.; Costa, J. E. R.


    O estudo das variações do raio solar durante o ciclo de atividades do Sol e das diferenças em relação à sua distribuição angular nos fornece informações importantes sobre as mudanças na estrutura da atmosfera solar. Neste trabalho foram analisados mais de 3600 mapas do Sol em 17 GHz obtidos pelo Rádio Heliógrafo de Nobeyama (NoRH), durante 1 ciclo de atividade solar (1992-2003). O raio solar foi definido no ponto onde a temperatura de brilho do mapa era equivalente à metade da temperatura do Sol calmo (temperatura mais comum no mapa).Em relação à sua variação ao longo do ciclo solar, o estudo foi dividido em duas partes: a) ajuste de uma circunferência a pontos distribuídos ao redor do Sol todo. Este estudo mostrou uma variação correlacionada com o ciclo de atividade do Sol. b) ajuste da circunferência a pontos situados somente nas regiões polares. Neste caso os resultados mostraram que o raio polar sofre pouca variação durante o ciclo, com tendência à anticorrelação com este. Além disto, a média do raio polar, durante o período analisado, foi 1" menor que o raio medido no Sol todo. Para estudar a distribuição angular do raio solar, comparamos a média da distribuição de 10 mapas no período de mínima atividade solar com a média de 10 mapas no período de máximo, este estudo mostrou um grande aumento do raio na região equatorial no período de máxima atividade solar. As medidas do raio foram usadas como um dos parâmetros para a criação de um modelo atmosférico (além da temperatura de brilho do Sol e do abrilhantamento do limbo observado), onde mostramos que um modelo atmosférico com a região de transição situada a 3500 km fornece um raio 5" menor que as medidas observacionais. Esta incompatibilidade do modelo com os dados observacionais foi contornada com a inclusão de espículas, estas fazem com que o raio solar aumente proporcionalmente à altura que estas atingem na atmosfera solar. A anticorrelação do raio

  12. Self-organization in magnetic flux ropes

    NASA Astrophysics Data System (ADS)

    Lukin, Vyacheslav S.


    This cross-disciplinary special issue on 'Self-organization in magnetic flux ropes' follows in the footsteps of another collection of manuscripts dedicated to the subject of magnetic flux ropes, a volume on 'Physics of magnetic flux ropes' published in the American Geophysical Union's Geophysical Monograph Series in 1990 [1]. Twenty-four years later, this special issue, composed of invited original contributions highlighting ongoing research on the physics of magnetic flux ropes in astrophysical, space and laboratory plasmas, can be considered an update on our state of understanding of this fundamental constituent of any magnetized plasma. Furthermore, by inviting contributions from research groups focused on the study of the origins and properties of magnetic flux ropes in a variety of different environments, we have attempted to underline both the diversity of and the commonalities among magnetic flux ropes throughout the solar system and, indeed, the universe. So, what is a magnetic flux rope? The answer will undoubtedly depend on whom you ask. A flux rope can be as narrow as a few Larmor radii and as wide as the Sun (see, e.g., the contributions by Heli Hietala et al and by Angelous Vourlidas). As described below by Ward Manchester IV et al , they can stretch from the Sun to the Earth in the form of interplanetary coronal mass ejections. Or, as in the Swarthmore Spheromak Experiment described by David Schaffner et al , they can fit into a meter-long laboratory device tended by college students. They can be helical and line-tied (see, e.g., Walter Gekelman et al or J Sears et al ), or toroidal and periodic (see, e.g., John O'Bryan et al or Philippa Browning et al ). They can form in the low plasma beta environment of the solar corona (Tibor Török et al ), the order unity beta plasmas of the solar wind (Stefan Eriksson et al ) and the plasma pressure dominated stellar convection zones (Nicholas Nelson and Mark Miesch). In this special issue, Setthivoine You

  13. EHD Approach to Tornadic Thunderstorms and Methods of Their Destruction

    NASA Astrophysics Data System (ADS)

    Kikuchi, H.


    In many cases, tornadoes are accompanied or involved by lightning discharges and are thought to be com- posed of uncharged and charged components different from each other in terms of velocity, vorticity, heli- city, and appearance (shape and luminosity). Their visible dark portion may correspond to uncharged tor- nadoes, while luminous or bright part may involve charged tornadoes with return strokes. Usually, un- charged tornadoes have been considered to be ascending hot streams of thermohydrodynamic origin. This is the conventional theory of tornadoes, based on hydrodynamics (HD) or thermohydrodynamics (THD) but does not consider electrical effects that are really significant in tornadic thunderstorms..It has been shown, however, that a new electrohydrodynamics (EHD) established and developed over the last more than a decade is applicable to tornadic thunderstorms with lightning. This paper summarizes such an EHD approach and proposes the methods of tornado destruction based on EHD. Space charge and electric field configurations in tornadic thunderstorms are considered to be quadrupole-like, taking into account the cloud-charge images onto the ground. Accordingly, dynamics of particles and EHD flows in an electric quadrupole forming an electric cusp and mirror can straightly apply to those circumstances. When the gas pressure is below the breakdown threshold, there occur helical motion of particles, not only charged but also even uncharged, and/or vortex generation. While for gases whose pressure is beyond the breakdown threshold, the following basic processes succeed one after another. When the grain is uncharged, a dis- charge channel is formed towards each pole as a result of X-type reconnection. For a negatively or posi- tively charged grain, I-type reconnection occurs between the grain and positive or negative poles, respect- ively. For uncharged two grains, O-type reconnection between both grains could be involved in addition to X-type between each pole

  14. Poster Session C

    PubMed Central


    , Cambridge, MA, USA; 3Howard Hughes Medical Institute Massachussets General Hospital, Boston, MA, USA A challenge to obtaining high quality organellar proteomes is the difficulty of purifying organelles to homogeneity without loss of crucial components. Furthermore, many subcellular regions of great importance cannot be purified at all, and hence their proteomes are not known. We present a live cell proximity-dependent enzymatic biotinylation strategy that bypasses the need for organellar purification and produces highly specific proteomic maps of multiple subcellular regions. The tagging enzyme is APEX2, an evolved variant of soybean ascorbate peroxidase that generates short-lived biotin-phenoxyl radicals for covalent tagging in vivo. We used this approach to generate proteomes of 137 and 637 proteins, respectively, for the outer mitochondrial membrane and endoplasmic reticulum membranes. Our list contains numerous novel proteins not previously associated with these cellular regions that potentially point to novel biological functions. C.8 Optimization of Glycopeptide Enrichment Using Lectin Weak Affinity Chromatography Jason Maynard, Krista Kaasik, A.L. Burlingame Department of Pharmaceutical Chemistry, School of, San Francisco, CA, USA O-linked N-acetylglucosamine (O-GlcNAc) modification of serine and threonine residues in cytosolic and nuclear proteins has been implicated in diverse molecular processes within the cell from regulation of the cell cycle to synaptic plasticity. Cellular levels of O-GlcNAc are sensitive to a number of nutrients including glucose and glutamine. Misregulation of O-GlcNAc has also been implicated in several human diseases, including diabetes, cardiac infarction, and neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. Although ubiquitous within the cell and discovered over thirty years ago, large-scale studies of O-GlcNAc have lagged far behind those of other post-translational modifications, including phosphorylation

  15. Poster Session B

    PubMed Central


    proteins which are fundamental regulators of PPARg and the fat cell commitment decision. B.6 Application of Quantitative and Functional Phosphoproteomics In Study of Ethylene Signaling Ning Li 1 1The Hong Kong University of Science and Technology, Hong Kong, China Ethylene is a major plant hormone that regulates a diverse aspect of plant growth and development. The regulatory roles of ethylene in plants include promotion of leaf and flower petal senescence, yellowing and abscission, as well as promotion of fruit abscission and ripening. This key hormone is also involved in regulation of a number of plant biotic and abiotic stress responses. A dramatic effect of ethylene on tropic response is the dual-and-opposing effect of ethylene on stem negative gravitropic response, in which short-term ethylene treatment (0.5 hour) appears to inhibit stem bending up following re-orientation of inflorescence of Arabidopsis. In contrast, a long-term treatment (12 hours) stimulates gravitropic response and promote stem curve up faster. This time-dependent and dose- independent dual-and-opposing effect of ethylene on stem gravitropism may involve multiple signaling pathways. Stable isotope metabolic labeling-based quantitative phosphoproteomics performed on ein2–5, ctr1–1 and rcn1–1 ethylene signaling mutants indeed confirmed the time-dependent protein phosphorylation changes and some of phosphorylation events are independent to ein2 loss-of- function gene in response to ethylene treatment. Functional studies on the phosphorylated transcription factor ERF110 isoform suggest that it is required for the control of flowering time via multiple ethylene signaling pathways. B.7 Intact N- and O-linked Glycopeptide Identification from HCD Data Using Byonic Katalin F. Medzihradszky1, Jason Maynard1, Krista Kaasik1, Marshall Bern2 1University of California, San Francisco, CA, USA; 2Protein Metrics, San Carlos, CA, USA The importance of high quality analysis of glycosylated proteins is steadily