... Global Health Researchers Fogarty scholar helps Zambians fight cervical cancer Medical student and Fogarty scholar Krista Pfaendler (right) assists with surgery on a patient with cervical cancer in Zambia. Photo courtesy of Krista Pfaendler An ...
Heischman, Daniel R.
In "Speaking of Faith," radio journalist Krista Tippett recalls the time when she began to recognize the hypocrisy and contradictions in the behavior of the people around her. Tippett's experience is not only far from unusual, it is formative. It led her to make some important decisions in her life, including the desire never to live a life of…
... ``information overload'' for consumers, and detract from the primary purpose of the credit score information... respective risk-based pricing rules to require disclosure of credit scores and information relating to credit... rules are effective August 15, 2011. FOR FURTHER INFORMATION CONTACT: Board: Krista P. Ayoub,...
Eating Disorders: The Impact on Children and Families. Hearing before the Select Committee on Children, Youth, and Families. House of Representatives, One Hundredth Congress, First Session (San Francisco, CA, July 31, 1987).
Congress of the U.S., Washington, DC. House Select Committee on Children, Youth, and Families.
The text of a Congressional hearing to examine the impact of eating disorders on children and families is presented in this document. Testimony by the following witnesses is included: (1) Krista Brown, eating disorder victim, and her mother, Susan Brown; (2) Robert B. Duncan, a hospital president; (3) Patricia Fallon, a clinical psychogist; (4)…
Forrest, Krista D.
The author, Krista D. Forrest, Professor of Psychology, University of Nebraska at Kearney, reports on what it would take to create a "Utopian university," a campus of the future where faculty members' scholarship of teaching and learning (SoTL) has gone on to change departments and as the departments changed, so did the institution.…
Lahti, I.; Korja, T.; Petersen, L. B.
LITHOSPHERIC CONDUCTIVITY ALONG THE GGT/SVEKA TRANSECT IN THE FENNOSCANDIAN SHIELD I. Lahti (1), T. Korja (1), L. Pedersen (2) and BEAR Working Group (1) Department of Geophysics, University of Oulu, Finland (2) Department of Earth Sciences, University of Uppsala, Sweden email@example.com The GGT/SVEKA transect traverses the main tectonic units in the central part of the Fennoscandian Shield in NE-SW direction. These units are the Archaean Karelian Province in the northeast and several Palaeoproterozoic arc complexes in the Svecofennian Domain in the southwest. Since 1985 over 150 magnetotelluric (MT) soundings of which 140 are short period and 10 long period soundings have been made in the survey area. We have performed several 2-D Occam inversions of the MT data using the REBOCC code (Siripunvaraporn and Egbert, 2000) to generate smooth conductivity models for the survey area. The best fitting model with the RMS error below 3.0% is obtained by using the determinant of impedance tensor as the inverted parameter. Highly conductive dipping conductors at both sides of the boundary zone between the arc complexes in southern and central Finland are seen in the final model. Both conductors represent borders of major crustal segments possibly indicating two subductions in the research area. In contrast, only minor conductivity variations are seen at the lithological boundary between the Karelian and Svecofennian domains in central Finland whereas a southwestward dipping conductor beneath the Palaeoproterozoic Kainuu Belt is revealed. The conductor suggests the presence of Palaeoproterozoic graphite bearing sedimentary rocks beneath the Archaean rocks of the Iisalmi complex. Lower crustal conductor is absent to NE from the Kainuu Belt while the conductor is present in the Palaeoproterozoic Svecofennian Domain to southwest from the Kainuu Belt. Thus, the main conductivity boundary between the Archaean and Palaeoproterozoic lithosphere is located beneath the Kainuu Belt
Müller, Herbert; Reissner, Michael; Steiner, Walter; Wiesinger, Günter
. The positive atmosphere, the high attendance in the sessions and the lively discussions made the conference a great success and a memorable event. It was pointed out, that Mössbauer spectroscopy is still an interesting and powerful method with great opportunities in the future. Herbert Müller (Secretary) Michael Reissner (Chairman) This book is dedicated to our colleagues Nicol Malcom, who could not come, because he suddenly died a few weeks in advance to the conference and Hercilio Rechenberg, who died on his way home from Vienna. Conference photograph Conference Organisation Local Organizing Committee Reissner Michael (Chairman)Müller Herbert (Conference Secretary) Amthauer Georg Lottermoser WernerSteiner Walter Bauer Ernst Michor Herwig Vogl Gero Bühler-Paschen Silke Müller Martin Waas Monika Grodzicki Michael Redhammer Günther Wiesinger Günter Grössinger Roland Sassik Herbert Hilscher Gerfried Sepiol Bogdan International Programme Committee Amthauer Georg Gütlich Philipp Steiner Walter Baggio-Saitovich Elisa Litterst Fred Jochen Trautwein Alfred Xaver Berry Frank Long Gary Vogl Gero Felner Israel Nagy Denes Lajos Yoshida Yutaka Greneche Jean-Marc Rüffer Rudolf International Advisory Board Alp E ErcanGénin Jean-Marie Baggio-Saitovitch Elisa Greneche Jean-Marc Miglierini Marcel Balogh Judit Grodzicki Michael Musić Svetozar Bender Koch Christian Gütlich Philipp Nagy Dénes Lajos Berry Frank Häggström Lennart Nishida Tetsuaki Brown Dennis Hanzel Darko Pérez Alcázar German Campbell Stewart Hassaan Mohamed Yousri Rüffer Rudolf Carbucicchio Massimo Jumas Jean-Claude Ryan Dominic H Croci Simonetta Kadyrzhanov Kariat Sanchez Francisco Di Naili Katila Toivo Schünemann Volker Elzain Mohamed Kim Chul Sung Stanek Jan Fabris José Domingos Klingelhöfer Göstar Stevens John Felner Israel Langouche Guido Suzdalev Igor P Fern George R Lyubutin Igor S Szymanski Krzysztof Forder Sue D Marco Jose F Waanders Frans Gajbhiye Nandeo Mašlaň Miroslav Yoshida Yutaka
, Cambridge, MA, USA; 3Howard Hughes Medical Institute Massachussets General Hospital, Boston, MA, USA A challenge to obtaining high quality organellar proteomes is the difficulty of purifying organelles to homogeneity without loss of crucial components. Furthermore, many subcellular regions of great importance cannot be purified at all, and hence their proteomes are not known. We present a live cell proximity-dependent enzymatic biotinylation strategy that bypasses the need for organellar purification and produces highly specific proteomic maps of multiple subcellular regions. The tagging enzyme is APEX2, an evolved variant of soybean ascorbate peroxidase that generates short-lived biotin-phenoxyl radicals for covalent tagging in vivo. We used this approach to generate proteomes of 137 and 637 proteins, respectively, for the outer mitochondrial membrane and endoplasmic reticulum membranes. Our list contains numerous novel proteins not previously associated with these cellular regions that potentially point to novel biological functions. C.8 Optimization of Glycopeptide Enrichment Using Lectin Weak Affinity Chromatography Jason Maynard, Krista Kaasik, A.L. Burlingame Department of Pharmaceutical Chemistry, School of, San Francisco, CA, USA O-linked N-acetylglucosamine (O-GlcNAc) modification of serine and threonine residues in cytosolic and nuclear proteins has been implicated in diverse molecular processes within the cell from regulation of the cell cycle to synaptic plasticity. Cellular levels of O-GlcNAc are sensitive to a number of nutrients including glucose and glutamine. Misregulation of O-GlcNAc has also been implicated in several human diseases, including diabetes, cardiac infarction, and neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. Although ubiquitous within the cell and discovered over thirty years ago, large-scale studies of O-GlcNAc have lagged far behind those of other post-translational modifications, including phosphorylation
proteins which are fundamental regulators of PPARg and the fat cell commitment decision. B.6 Application of Quantitative and Functional Phosphoproteomics In Study of Ethylene Signaling Ning Li 1 1The Hong Kong University of Science and Technology, Hong Kong, China Ethylene is a major plant hormone that regulates a diverse aspect of plant growth and development. The regulatory roles of ethylene in plants include promotion of leaf and flower petal senescence, yellowing and abscission, as well as promotion of fruit abscission and ripening. This key hormone is also involved in regulation of a number of plant biotic and abiotic stress responses. A dramatic effect of ethylene on tropic response is the dual-and-opposing effect of ethylene on stem negative gravitropic response, in which short-term ethylene treatment (0.5 hour) appears to inhibit stem bending up following re-orientation of inflorescence of Arabidopsis. In contrast, a long-term treatment (12 hours) stimulates gravitropic response and promote stem curve up faster. This time-dependent and dose- independent dual-and-opposing effect of ethylene on stem gravitropism may involve multiple signaling pathways. Stable isotope metabolic labeling-based quantitative phosphoproteomics performed on ein2–5, ctr1–1 and rcn1–1 ethylene signaling mutants indeed confirmed the time-dependent protein phosphorylation changes and some of phosphorylation events are independent to ein2 loss-of- function gene in response to ethylene treatment. Functional studies on the phosphorylated transcription factor ERF110 isoform suggest that it is required for the control of flowering time via multiple ethylene signaling pathways. B.7 Intact N- and O-linked Glycopeptide Identification from HCD Data Using Byonic Katalin F. Medzihradszky1, Jason Maynard1, Krista Kaasik1, Marshall Bern2 1University of California, San Francisco, CA, USA; 2Protein Metrics, San Carlos, CA, USA The importance of high quality analysis of glycosylated proteins is steadily