19 CFR 177.0 - Scope.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Customs files), part 133 (relating to disputed claims of piratical copying of copyrighted matter), subpart... 19 Customs Duties 2 2014-04-01 2014-04-01 false Scope. 177.0 Section 177.0 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY (CONTINUED...

19 CFR 177.0 - Scope.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Customs files), part 133 (relating to disputed claims of piratical copying of copyrighted matter), subpart... 19 Customs Duties 2 2011-04-01 2011-04-01 false Scope. 177.0 Section 177.0 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY (CONTINUED...

21 CFR 862.1770 - Urea nitrogen test system.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Urea nitrogen test system. 862.1770 Section 862....1770 Urea nitrogen test system. (a) Identification. A urea nitrogen test system is a device intended to measure urea nitrogen (an end-product of nitrogen metabolism) in whole blood, serum, plasma, and urine...

21 CFR 862.1770 - Urea nitrogen test system.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Urea nitrogen test system. 862.1770 Section 862....1770 Urea nitrogen test system. (a) Identification. A urea nitrogen test system is a device intended to measure urea nitrogen (an end-product of nitrogen metabolism) in whole blood, serum, plasma, and urine...

21 CFR 862.1770 - Urea nitrogen test system.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Urea nitrogen test system. 862.1770 Section 862....1770 Urea nitrogen test system. (a) Identification. A urea nitrogen test system is a device intended to measure urea nitrogen (an end-product of nitrogen metabolism) in whole blood, serum, plasma, and urine...

21 CFR 862.1770 - Urea nitrogen test system.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Urea nitrogen test system. 862.1770 Section 862....1770 Urea nitrogen test system. (a) Identification. A urea nitrogen test system is a device intended to measure urea nitrogen (an end-product of nitrogen metabolism) in whole blood, serum, plasma, and urine...

21 CFR 862.1770 - Urea nitrogen test system.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Urea nitrogen test system. 862.1770 Section 862....1770 Urea nitrogen test system. (a) Identification. A urea nitrogen test system is a device intended to measure urea nitrogen (an end-product of nitrogen metabolism) in whole blood, serum, plasma, and urine...

Long-lasting Extreme Magnetic Storm Activities in 1770 Found in Historical Documents

NASA Astrophysics Data System (ADS)

Hayakawa, Hisashi; Iwahashi, Kiyomi; Ebihara, Yusuke; Tamazawa, Harufumi; Shibata, Kazunari; Knipp, Delores J.; Kawamura, Akito D.; Hattori, Kentaro; Mase, Kumiko; Nakanishi, Ichiro; Isobe, Hiroaki

2017-12-01

Dim red aurora at low magnetic latitudes is a visual and recognized manifestation of magnetic storms. The great low-latitude auroral displays seen throughout East Asia on 1770 September 16-18 are considered to manifest one of the greatest storms. Recently found, 111 historical documents in East Asia attest that these low-latitude auroral displays appeared in succession for almost nine nights during 1770 September 10-19 in low magnetic latitude areas (<30°). This suggests that the duration of the great magnetic storm is much longer than usual. Sunspot drawings from 1770 reveal that the sunspot areas were twice as large as those observed in another great storm of 1859, which substantiates these unusual storm activities in 1770. These spots likely ejected several huge, sequential magnetic structures in short duration into interplanetary space, resulting in spectacular worldwide aurorae in mid-September of 1770. These findings provide new insight into the history, duration, and effects of extreme magnetic storms that may be valuable for those who need to mitigate against extreme events.

21 CFR 892.1770 - Diagnostic x-ray tube mount.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Diagnostic x-ray tube mount. 892.1770 Section 892...) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1770 Diagnostic x-ray tube mount. (a) Identification. A diagnostic x-ray tube mount is a device intended to support and to position the diagnostic x...

21 CFR 892.1770 - Diagnostic x-ray tube mount.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Diagnostic x-ray tube mount. 892.1770 Section 892...) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1770 Diagnostic x-ray tube mount. (a) Identification. A diagnostic x-ray tube mount is a device intended to support and to position the diagnostic x...

21 CFR 892.1770 - Diagnostic x-ray tube mount.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Diagnostic x-ray tube mount. 892.1770 Section 892...) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1770 Diagnostic x-ray tube mount. (a) Identification. A diagnostic x-ray tube mount is a device intended to support and to position the diagnostic x...

21 CFR 892.1770 - Diagnostic x-ray tube mount.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Diagnostic x-ray tube mount. 892.1770 Section 892...) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1770 Diagnostic x-ray tube mount. (a) Identification. A diagnostic x-ray tube mount is a device intended to support and to position the diagnostic x...

21 CFR 892.1770 - Diagnostic x-ray tube mount.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Diagnostic x-ray tube mount. 892.1770 Section 892...) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1770 Diagnostic x-ray tube mount. (a) Identification. A diagnostic x-ray tube mount is a device intended to support and to position the diagnostic x...

40 CFR 60.1770 - What must I do if any of my continuous emission monitoring systems are temporarily unavailable to...

Code of Federal Regulations, 2011 CFR

2011-07-01

... emission monitoring systems are temporarily unavailable to meet the data collection requirements? 60.1770... Emission Monitoring § 60.1770 What must I do if any of my continuous emission monitoring systems are... alternate methods for collecting data when systems malfunction or when repairs, calibration checks, or zero...

40 CFR 60.1770 - What must I do if any of my continuous emission monitoring systems are temporarily unavailable to...

Code of Federal Regulations, 2010 CFR

2010-07-01

... emission monitoring systems are temporarily unavailable to meet the data collection requirements? 60.1770... Emission Monitoring § 60.1770 What must I do if any of my continuous emission monitoring systems are... alternate methods for collecting data when systems malfunction or when repairs, calibration checks, or zero...

7 CFR 1770.10 - General.

Code of Federal Regulations, 2010 CFR

2010-01-01

... (CONTINUED) ACCOUNTING REQUIREMENTS FOR RUS TELECOMMUNICATIONS BORROWERS Uniform System of Accounts § 1770.10... accounting system accounts to be maintained by telecommunications borrowers of the Rural Utilities Service. ...

7 CFR 1770.1 - General.

Code of Federal Regulations, 2010 CFR

2010-01-01

... (CONTINUED) ACCOUNTING REQUIREMENTS FOR RUS TELECOMMUNICATIONS BORROWERS Preservation of Records § 1770.1..., records, memoranda, documents, papers, and correspondence prepared by or on behalf of the borrower as well...

7 CFR 1770.3 - Index of records.

Code of Federal Regulations, 2010 CFR

2010-01-01

... (CONTINUED) ACCOUNTING REQUIREMENTS FOR RUS TELECOMMUNICATIONS BORROWERS Preservation of Records § 1770.3... maintained. The master index shall be subject to review by RUS and RUS shall reserve the right to add records...

Production of poly-beta-hydroxybutyrate (PHB) by Alcaligenes latus from maple sap.

PubMed

Yezza, Abdessalem; Halasz, Annamaria; Levadoux, Wayne; Hawari, Jalal

2007-11-01

Maple sap, an abundant natural product especially in Canada, is rich in sucrose and thus may represent an ideal renewable feedstock for the production of a wide variety of value-added products. In the present study, maple sap or sucrose was employed as a carbon source to Alcaligenes latus for the production of poly-beta-hydroxybutyrate (PHB). In shake flasks, the biomass obtained from both the sap and sucrose were 4.4 +/- 0.5 and 2.9 +/- 0.3 g/L, and the PHB contents were 77.6 +/- 1.5 and 74.1 +/- 2.0%, respectively. Subsequent batch fermentation (10 L sap) resulted in the formation of 4.2 +/- 0.3 g/L biomass and a PHB content of 77.0 +/- 2.6%. The number average molecular weights of the PHB produced by A. latus from maple sap and pure sucrose media were 300 +/- 66 x 10(3) and 313 +/- 104 x 10(3) g/mol, respectively. Near-infrared, (1)H magnetic resonance imaging (MRI), and (13)C-MRI spectra of the microbially produced PHB completely matched those obtained with a reference material of poly[(R)-3-hydroxybutyric acid]. The polymer was found to be optically active with [alpha](25) (D) equaled to -7.87 in chloroform. The melting point (177.0 degrees C) and enthalpy of fusion (77.2 J/g) of the polymer were also in line with those reported, i.e., 177 degrees C and 81 J/g, respectively.

7 CFR 1770.26 - General.

Code of Federal Regulations, 2011 CFR

2011-01-01

... (CONTINUED) ACCOUNTING REQUIREMENTS FOR RUS TELECOMMUNICATIONS BORROWERS Accounting Interpretations § 1770.26 General. (a) The standard provisions of the security instruments utilized by the Rural Utilities Service (RUS) and the Rural Telephone Bank (RTB) for all telecommunications borrowers require borrowers to at...

Inclined Zenith Aurora over Kyoto on 17 September 1770: Graphical Evidence of Extreme Magnetic Storm

NASA Astrophysics Data System (ADS)

Kataoka, Ryuho; Iwahashi, Kiyomi

2017-10-01

Red auroras were observed in Japan during an extreme magnetic storm that occurred on 17 September 1770. We show new evidence that the red aurora extended toward the zenith of Kyoto around midnight. The basic appearance of the historical painting of the red aurora is geometrically reproduced based on the inclination of the local magnetic field and a detailed description in a newly discovered diary. The presence of the inclined zenith aurora over Kyoto suggests that the intensity of the September 1770 magnetic storm is comparable to, or slightly larger than that of the September 1859 Carrington storm.

21 CFR 886.1770 - Manual refractor.

Code of Federal Regulations, 2010 CFR

2010-04-01

... DEVICES OPHTHALMIC DEVICES Diagnostic Devices § 886.1770 Manual refractor. (a) Identification. A manual refractor is a device that is a set of lenses of varous dioptric powers intended to measure the refractive error of the eye. (b) Classification. Class I (general controls). The device is exempt from the...

20 CFR 404.1770 - Decision by hearing officer.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 404.1770 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY... the close of the hearing, the hearing officer shall issue a decision or certify the case to the...., failure to pay dues or to complete continuing legal education requirements), that will not disqualify the...

20 CFR 404.1770 - Decision by hearing officer.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 404.1770 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY... the close of the hearing, the hearing officer shall issue a decision or certify the case to the...., failure to pay dues or to complete continuing legal education requirements), that will not disqualify the...

Identification of a founder BRCA1 mutation in the Moroccan population.

PubMed

Quiles, F; Teulé, À; Martinussen Tandstad, N; Feliubadaló, L; Tornero, E; Del Valle, J; Menéndez, M; Salinas, M; Wethe Rognlien, V; Velasco, A; Izquierdo, A; Capellá, G; Brunet, J; Lázaro, C

2016-10-01

Breast cancer (BC) is the most frequent cancer among women in Morocco. However, the role of the most prevalent BC-predisposing genes, BRCA1 and BRCA2, has been largely unexplored. To help define the role of BRCA1 in BC in Morocco, we characterized the first potential BRCA1 founder mutation in this population. Genetic testing of BRCA1 and BRCA2 in BC high-risk families identified mutation BRCA1 c.5309G>T, p.(Gly1770Val) or G1770V in five independent families from Morocco, suggesting a founder effect. To confirm this hypothesis, haplotype construction was performed using seven intragenic and flanking BRCA1 microsatellite markers. Clinical data were also compiled. Clinical data from carriers of mutation G1770V correspond to data from carriers of BRCA1 pathogenic mutations. Microsatellite analysis showed a common haplotype for the five families in a region comprising 1.54 Mb, confirming G1770V as the first specific founder BRCA1 mutation in the Moroccan population. Our findings contribute to a better understanding of BC genetics in the Moroccan population. Nevertheless, comprehensive studies of mutation G1770V in large series of BC patients from Morocco are needed to assess the real prevalence of this mutation and to improve genetic testing and risk assessment in this population. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

20 CFR 404.1770 - Decision by hearing officer.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 404.1770 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY... the close of the hearing, the hearing officer will issue a decision or certify the case to the Appeals...., failure to pay dues or to complete continuing legal education requirements), that will not disqualify the...

20 CFR 404.1770 - Decision by hearing officer.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 404.1770 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY... the close of the hearing, the hearing officer will issue a decision or certify the case to the Appeals...., failure to pay dues or to complete continuing legal education requirements), that will not disqualify the...

20 CFR 404.1770 - Decision by hearing officer.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 404.1770 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY... the close of the hearing, the hearing officer will issue a decision or certify the case to the Appeals...., failure to pay dues or to complete continuing legal education requirements), that will not disqualify the...

38 CFR 17.70 - Written decision following a hearing.

Code of Federal Regulations, 2011 CFR

2011-07-01

... shall consider the safety and health of the residents of the community residential care facility and the... AFFAIRS MEDICAL Community Residential Care § 17.70 Written decision following a hearing. (a) The hearing... community residential care facility's noncompliance with VA standards shall be based on the preponderance of...

38 CFR 17.70 - Written decision following a hearing.

Code of Federal Regulations, 2010 CFR

2010-07-01

... shall consider the safety and health of the residents of the community residential care facility and the... AFFAIRS MEDICAL Community Residential Care § 17.70 Written decision following a hearing. (a) The hearing... community residential care facility's noncompliance with VA standards shall be based on the preponderance of...

New Comment on Gibbs Density Surface of Fluid Argon: Revised Critical Parameters, L. V. Woodcock, Int. J. Thermophys. (2014) 35, 1770-1784

NASA Astrophysics Data System (ADS)

Umirzakov, I. H.

2018-01-01

The author comments on an article by Woodcock (Int J Thermophys 35:1770-1784, 2014), who investigates the idea of a critical line instead of a single critical point using the example of argon. In the introduction, Woodcock states that "The Van der Waals critical point does not comply with the Gibbs phase rule. Its existence is based upon a hypothesis rather than a thermodynamic definition". The present comment is a response to the statement by Woodcock. The comment mathematically demonstrates that a critical point is not only based on a hypothesis that is used to define values of two parameters of the Van der Waals equation of state. Instead, the author argues that a critical point is a direct consequence of the thermodynamic phase equilibrium conditions resulting in a single critical point. It is shown that the thermodynamic conditions result in the first and second partial derivatives of pressure with respect to volume at constant temperature at a critical point equal to zero which are usual conditions of an existence of a critical point.

76 FR 56491 - Culturally Significant Objects Imported for Exhibition Determinations: “Adapting the Eye: An...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-13

... DEPARTMENT OF STATE [Public Notice: 7580] Culturally Significant Objects Imported for Exhibition Determinations: ``Adapting the Eye: An Archive of the British in India, 1770-1830'' Summary: Notice is hereby... objects to be included in the exhibition ``Adapting the Eye: An Archive of the British in India, 1770-1830...

78 FR 70907 - Implementation of the Commercial Advertisement Loudness Mitigation (CALM) Act

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-27

... television industry can monitor and control the loudness level of digital TV programming. The rules took... references ITU-R BS.1770-3.''). As explained in the CALM Act Report and Order, the ITU-R BS.1770 measurement... includes improved guidance for measuring the loudness of surround programming in both its multichannel...

Annual Tropical Cyclone Report, 1982.

DTIC Science & Technology

1982-01-01

intensity forecast are made once each day by processed at AFGWC is recorded on-board applying the Dvorak technique (NOAA Technical the spacecraft as it...tropical cyclone. Season totals and the 700 mb pressure surface within the percentages are also indicated. vortex recorded in meters. 7 Z ;l__...16 TY GORDON 27 AUG - 5 SEP 10 39 100 944 2014 17 TS HOPE 4 SEP - 6 SEP 3 10 #0 979 630 18 TY IRVING 5 SEP - 16 SEP 12 44 90 952 1770 19 TY JUDY 5 SEP

Kant's disputation of 1770: the dissertation and the communication of knowledge in early modern Europe.

PubMed

Chang, Kevin

2007-06-01

Kant's disputation of 1770 at his inauguration as the metaphysics professor at Königsberg is a good example of the nature of the early modern dissertation and its use as a means of communicating knowledge. The public disputation played an important part in the teaching, examination, publication and ceremonial life of the medieval university. Originally prepared as a text for the public disputation, the dissertation communicated the teachings of individual scholars and institutions and was used by eminent early modern scholars to introduce their ideas and findings. Kant's use of his 1770 disputation also reveals the different channels of communication, both private and public, that paid close attention to knowledge published in dissertations.

Chanute AFB, Rantoul, Illinois. Revised Uniform Summary of Surfae Weather Observations (RUSSWO). Parts A-F

DTIC Science & Technology

1972-10-27

FROM HOURLY OBSERVATIONS) 148b__ (- td ,4uTs, ,A-g ILL IN ,IS/RANTQIJL 17-70 F F 1)STATION STATION RARE YEARS NORTH C ALL ;lN IT14FR 1200-1400 CLASS...SPEED MEAN (KNTS) 1 • 3 4.*6 7 - 10 11 •16 17 -. 21 22 *27 28 • 33 34.• 40 41 •47 48 •55 ->56 % I WIND DIR. t . SPEED N _ 0 .2 . 0 5 8,4 NrE , td 1.4...PERCENTAGE FREQUENCY OF WIND *DIRECTION AND SPEED (FROM HOURLY OBSERVATIONS) S Ij) CAjhitblf td - i ILLINJUS/pA1T;JL 37-70 _ - L STATION STATION RAMS TZAIS

A Correlation of Welding Solidification Parameters to Weld Macrostructure

DTIC Science & Technology

1992-06-18

BY THE START PROGRAMS. C C PROGRAM GVPLOT C DIMENSION TEMP(27,27,8),ZMELT(27,27),GRAD(27,27),V(27,27) DIMENSION TMAP (27,8),TMAP2(17,5),TEMPIMP(5...DATA GRAD /729*0./ DATA TMAP /216*0.0/ TMELT = 1770.0 79 READ(I) TIME READ(l) (((TEMP(I,J,K),I=1,27),J=1,27),K=1,8) READ(l) VTORCH C C C ACQUIRE A...MAP OF MAX TEMPERATURES IN (X,Z) IN ORDER TO DEFINE THE C FUSION ZONE DO 300 1=1,27 DO 300 J= 1,27 DO 300 K=1,8 IF (TEMP(I,J,K).GT.TMAP(I,9-K)) TMAP (I

Garrison Dam/Lake Sakakawea Master Plan with Integrated Programmatic Environmental Assessment, Missouri River, Montana: Update of Design Memorandum MGR-107D

DTIC Science & Technology

2007-12-14

1770 1775 1780 1785 1790 1795 1800 1805 1810 1815 1820 1825 1830 1835 1840 1845 1850 1855 PO O L EL E VA TI O N (f t m sl ) Maximum Operating Pool...resources, invasive species, and T &E species, but to a lesser degree. These issues are dealt with under the normal operating procedures of the...Information Operations and Reports, 1215 Jefferson Davis Highway, Suite 1204, Arlington VA 22202-4302 Respondents should be aware that notwithstanding any

Integer ratios of S{sub n}/E{sub n} in {sup 40}Ca+n resonances suggesting two-oscillator excitations in the target nucleus

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ohkubo, Makio

2009-08-15

In s-wave neutron resonances of {sup 40}Ca at E{sub n}{<=}2.5 MeV, S{sub n}/E{sub n} for many levels is found to be of the form 17(n/m) where n, m are small integers. Statistical tests show small probabilities for the observed dispositions of many levels at E{sub n}=(j/k)(1/70)G (j, k; small integers). To meet the requirement of time periodicity of the compound nucleus at resonance, a breathing model is developed, where the excitation energies E{sub x} are written as a sum of inverse integers; E{sub x}=S{sub n}+E{sub n}=G{sigma}(1/k) (k: integer). In {sup 40}Ca+n, the separation energy S{sub n}=8362 keV is written asmore » S{sub n}=(17/70)G=(1/7+1/10)G, where G=34.4 MeV. G is almost equal to the Fermi energy of the nucleus. It is suggested that two oscillators of energy (1/7)G and (1/10)G are excited in {sup 40}Ca by neutron incidence, in which the recurrence energy (1/70)G is resonant with neutrons of energies at (j/k)(1/70)G, forming a simple compound nucleus.« less

Opportunity's View After Long Drive on Sol 1770 (Polar)

NASA Technical Reports Server (NTRS)

2009-01-01

NASA's Mars Exploration Rover Opportunity used its navigation camera to take the images combined into this full-circle view of the rover's surroundings just after driving 104 meters (341 feet) on the 1,770th Martian day, or sol, of Opportunity's surface mission (January 15, 2009).

This view is presented as a polar projection with geometric seam correction. North is at the top.

Tracks from the drive extend northward across dark-toned sand ripples and light-toned patches of exposed bedrock in the Meridiani Planum region of Mars. For scale, the distance between the parallel wheel tracks is about 1 meter (about 40 inches).

Prior to the Sol 1770 drive, Opportunity had driven less than a meter since Sol 1713 (November 17, 2008), while it used the tools on its robotic arm first to examine a meteorite called 'Santorini' during weeks of restricted communication while the sun was nearly in line between Mars and Earth, then to examine bedrock and soil targets near Santorini.

The rover's position after the Sol 1770 drive was about 1.1 kilometer (two-thirds of a mile) south southwest of Victoria Crater. Cumulative odometry was 13.72 kilometers (8.53 miles) since landing in January 2004, including 1.94 kilometers (1.21 miles) since climbing out of Victoria Crater on the west side of the crater on Sol 1634 (August 28, 2008).

Opportunity's View After Long Drive on Sol 1770

NASA Technical Reports Server (NTRS)

2009-01-01

NASA's Mars Exploration Rover Opportunity used its navigation camera to take the images combined into this full-circle view of the rover's surroundings just after driving 104 meters (341 feet) on the 1,770th Martian day, or sol, of Opportunity's surface mission (January 15, 2009).

Tracks from the drive extend northward across dark-toned sand ripples and light-toned patches of exposed bedrock in the Meridiani Planum region of Mars. For scale, the distance between the parallel wheel tracks is about 1 meter (about 40 inches).

Prior to the Sol 1770 drive, Opportunity had driven less than a meter since Sol 1713 (November 17, 2008), while it used the tools on its robotic arm first to examine a meteorite called 'Santorini' during weeks of restricted communication while the sun was nearly in line between Mars and Earth, then to examine bedrock and soil targets near Santorini.

The rover's position after the Sol 1770 drive was about 1.1 kilometer (two-thirds of a mile) south southwest of Victoria Crater. Cumulative odometry was 13.72 kilometers (8.53 miles) since landing in January 2004, including 1.94 kilometers (1.21 miles) since climbing out of Victoria Crater on the west side of the crater on Sol 1634 (August 28, 2008).

This view is presented as a cylindrical projection with geometric seam correction.

Opportunity's View After Long Drive on Sol 1770 (Vertical)

NASA Technical Reports Server (NTRS)

2009-01-01

NASA's Mars Exploration Rover Opportunity used its navigation camera to take the images combined into this full-circle view of the rover's surroundings just after driving 104 meters (341 feet) on the 1,770th Martian day, or sol, of Opportunity's surface mission (January 15, 2009).

This view is presented as a vertical projection with geometric seam correction. North is at the top.

Tracks from the drive extend northward across dark-toned sand ripples and light-toned patches of exposed bedrock in the Meridiani Planum region of Mars. For scale, the distance between the parallel wheel tracks is about 1 meter (about 40 inches).

Prior to the Sol 1770 drive, Opportunity had driven less than a meter since Sol 1713 (November 17, 2008), while it used the tools on its robotic arm first to examine a meteorite called 'Santorini' during weeks of restricted communication while the sun was nearly in line between Mars and Earth, then to examine bedrock and soil targets near Santorini.

The rover's position after the Sol 1770 drive was about 1.1 kilometer (two-thirds of a mile) south southwest of Victoria Crater. Cumulative odometry was 13.72 kilometers (8.53 miles) since landing in January 2004, including 1.94 kilometers (1.21 miles) since climbing out of Victoria Crater on the west side of the crater on Sol 1634 (August 28, 2008).

Vaccinols J-S, ten new salicyloid derivatives from the marine mangrove-derived endophytic fungus Pestalotiopsis vaccinii.

PubMed

Wang, Jun-Feng; Liang, Rui; Liao, Sheng-Rong; Yang, Bin; Tu, Zheng-Chao; Lin, Xiu-Ping; Wang, Bin-Gui; Liu, Yonghong

2017-07-01

Ten new salicyloid derivatives, namely vaccinols J-S (1-10), along with five known compounds (11-15) were isolated from Pestalotiopsis vaccinii (cgmcc3.9199) endogenous with the mangrove plant Kandelia candel (L.) Druce (Rhizophoraceae). Their structures including absolute configurations were established on the basis of spectroscopic analysis, optical rotation, CD spectra, quantum ECD calculations. To the best of our knowledge, vaccinol J (1) is the first example of salicyloid derivatives containing 2-methylfuran moiety. All of the new compounds were tested for their anti-enterovirus 7l (EV71) and cytotoxic activities. Among them, vaccinol J (1) exhibited in vitro anti-EV71 with IC 50 value of 30.7μM (IC 50 177.0μM for the positive control ribavirin). Copyright © 2017. Published by Elsevier B.V.

Opportunity's View After Long Drive on Sol 1770 (Stereo)

NASA Technical Reports Server (NTRS)

2009-01-01

[figure removed for brevity, see original site] Left-eye view of a color stereo pair for PIA11791 [figure removed for brevity, see original site] Right-eye view of a color stereo pair for PIA11791

NASA's Mars Exploration Rover Opportunity used its navigation camera to take the images combined into this stereo, full-circle view of the rover's surroundings just after driving 104 meters (341 feet) on the 1,770th Martian day, or sol, of Opportunity's surface mission (January 15, 2009).

This view combines images from the left-eye and right-eye sides of the navigation camera. It appears three-dimensional when viewed through red-blue glasses with the red lens on the left.

Tracks from the drive extend northward across dark-toned sand ripples and light-toned patches of exposed bedrock in the Meridiani Planum region of Mars. For scale, the distance between the parallel wheel tracks is about 1 meter (about 40 inches).

Prior to the Sol 1770 drive, Opportunity had driven less than a meter since Sol 1713 (November 17, 2008), while it used the tools on its robotic arm first to examine a meteorite called 'Santorini' during weeks of restricted communication while the sun was nearly in line between Mars and Earth, then to examine bedrock and soil targets near Santorini.

The rover's position after the Sol 1770 drive was about 1.1 kilometer (two-thirds of a mile) south southwest of Victoria Crater. Cumulative odometry was 13.72 kilometers (8.53 miles) since landing in January 2004, including 1.94 kilometers (1.21 miles) since climbing out of Victoria Crater on the west side of the crater on Sol 1634 (August 28, 2008).

This view is presented as a cylindrical-perspective projection with geometric seam correction.

[Ultraviolet spectrophotometric determination of tenoxicam using iodine solution as reagent].

PubMed

Mândrescu, Mariana; Spac, A F; Dorneanu, V

2009-01-01

For the tenoxicam determination (Nonsteroidal Antiinflammatory Drug - NSAID) it was developed a spectrophotometric method, after the coupling reaction of tenoxicam with iodine, in methanolic medium, with maximum of absorbance at 289 nm. The practical working conditions were established. In the 0.5 divided by 5.0 microg/mL range of tenoxicam concentration, were used 5 x 10(-3) M iodine solution and 0.5 N hydrocloric acid. The stability of product were evaluated for 30 minutes. The developed method was validated. The method showed a good linearity in the range of 0.5 divided 5.0 microg/mL (the correlation coefficient r = 0.9995). The detection limit (LD) was 0.14 microg/mL and the quantification limit (LQ) was 0.49 microg/mL. There were established the precison (RSD = 1.90%) and the accuracy-recovery in the range 97.27 divided by 102.56% with a mean recovery of 99.49%. The experimental results demonstrated a good sensibility. The specific absorptivity for this method is A1%(1 cm,289 nm) = 1770 much higher than tenoxicam in methanol (A1%(1 cm,360 nm) = 323).

Taste matters - effects of bypassing oral stimulation on hormone and appetite responses.

PubMed

Spetter, Maartje S; Mars, Monica; Viergever, Max A; de Graaf, Cees; Smeets, Paul A M

2014-10-01

The interaction between oral and gastric signals is an important part of food intake regulation. Previous studies suggest that bypassing oral stimulation diminishes the suppression of hunger and increases gastric emptying rate. However, the role of appetite hormones, like cholecystokinin-8 and ghrelin, in this process is still unclear. Our objective was to determine the contributions of gastric and oral stimulation to subsequent appetite and hormone responses and their effect on ad libitum intake. Fourteen healthy male subjects (age 24.6±3.8y, BMI 22.3±1.6kg/m(2)) completed a randomized, single-blinded, cross-over experiment with 3 treatment-sessions: 1) Stomach distention: naso-gastric infusion of 500mL/0kJ water, 2) Stomach distention with caloric content: naso-gastric infusion of 500mL/1770kJ chocolate milk, and 3) Stomach distention with caloric content and oral exposure: oral administration of 500mL/1770kJ chocolate milk. Changes in appetite ratings and plasma glucose, insulin, cholecystokinin-8, and active and total ghrelin concentrations were measured at fixed time-points up to 30min after infusion or oral administration. Subsequently, subjects consumed an ad libitum buffet meal. Oral administration reduced appetite ratings more than both naso-gastric infusions (P<0.0001). Gastric infusion of a caloric load increased insulin and cholecystokinin-8 and decreased total ghrelin concentrations more than ingestion (all P<0.0001). No differences in active ghrelin response were observed between conditions. Ad libitum intake did not differ between oral and gastric administration of chocolate milk (P>0.05). Thus, gastric infusion of nutrients induces greater appetite hormone responses than ingestion does. These data provide novel and additional evidence that bypassing oral stimulation not only affects the appetite profile but also increases anorexigenic hormone responses, probably driven in part by faster gastric emptying. This confirms the idea that learned associations between sensory characteristics and associated metabolic consequences serve to adapt hormone responses to nutrient content. These findings underscore the importance of oral stimulation in the regulation of food intake. Copyright © 2014 Elsevier Inc. All rights reserved.

Urban inoculation and the decline of smallpox mortality in eighteenth‐century cities—a reply to Razzell†

PubMed Central

Boulton, Jeremy; Schwarz, Leonard

2015-01-01

Smallpox was probably the single most lethal disease in eighteenth‐century Britain but was reduced to a minor cause of death by the mid‐nineteenth century due to vaccination programmes post‐1798. While the success of vaccination is unquestionable, it remains disputed to what extent the prophylactic precursor of vaccination, inoculation, reduced smallpox mortality in the eighteenth century. Smallpox was most lethal in urban populations, but most researchers have judged inoculation to have been unpopular in large towns. Recently, however, Razzell argued that inoculation significantly reduced smallpox mortality of adults and older children in London in the last third of the eighteenth century. This article uses demographic evidence from London and Manchester to confirm previous findings of a sudden fall in adult smallpox mortality and a rise in the importance of smallpox in early childhood c. 1770. The nature of these changes is consistent with an increase in smallpox transmission in London and Manchester after 1770 and indicates that smallpox inoculation was insufficient to reduce smallpox mortality in large towns. It remains unclear whether inoculation could have operated to enhance smallpox transmission or whether changes in the properties of the smallpox virus drove the intensification of smallpox mortality among young children post‐1770. PMID:26900169

Documentary-derived chronologies of rainfall variability in Antigua, Lesser Antilles, 1770-1890

NASA Astrophysics Data System (ADS)

Berland, A. J.; Metcalfe, S. E.; Endfield, G. H.

2013-03-01

This paper presents the first extensive reconstruction of precipitation variability in the Lesser Antilles using historical documentary sources. Over 13 250 items of documentation pertaining to Antigua from the period 1769-1890 were consulted, including missionary, plantation and governmental papers as well as contemporary scholarly publications. Based on the predominant meteorological conditions observed throughout the island, each "rain-year" (December-November) was assigned one of five classifications (very wet, wet, "normal", dry and very dry). Local weather references relating to seven plantations in central-eastern Antigua were grouped according to dry (December-April) and wet seasons (May-November), each of which were also categorised in the aforementioned manner. Results comprise individual island-wide and central-eastern Antiguan chronologies of relative precipitation levels, spanning the rain-years 1769-1770 to 1889-1890 and 1769-1770 to 1853-1854 respectively. The former is compared with available instrumental data for 1870-1890. Significant dry phases are identified in the rain-years 1775-1780, 1788-1791, 1820-1822, 1834-1837, 1844-1845, 1859-1860, 1862-1864, 1870-1874 and 1881-1882, while wet episodes were 1771-1774, 1833-1834, 1837-1838, 1841-1844, 1845-1846 and 1878-1881. Evidence for major wet and dry spells is presented and findings evaluated within wider historical and palaeoclimatic contexts.

Paleomagnetic study of 1765 Ma dyke swarm from the Singhbhum Craton: Implications to the paleogeography of India

NASA Astrophysics Data System (ADS)

Shankar, Ravi; Srinivasa Sarma, D.; Ramesh Babu, N.; Parashuramulu, V.

2018-05-01

We report the first key paleopole as a result of paleomagnetic study on a precisely dated 1765.3 ± 1.0 Ma WNW-ESE trending dyke swarm from Singhbhum Craton. This pole has been used in this study to propose the paleogeographic reconstruction of India with Baltica Craton and North China Craton. Incremental alternating field (AF) and thermal demagnetization, isolated high coercivity components with north to north-westerly declination and shallow negative inclination from 9 sampling sites which are representing different individual dykes. The primary origin of the ChRM is supported by the positive baked contact test. The WNW-ESE trending dykes yield a mean paleomagnetic direction with a declination = 329.2° and an inclination = -22.8° (k = 31.6; α95 = 9.3°). The positive bake contact test proves the primary nature of remanence. The pole position of Singhbhum Craton at 1765 Ma is 45°N, 311°E (dp = 5.2 and dm = 9.9). Paleogeographic reconstruction at ca. 1770 Ma, supported by geological, tectonic and metallogenic evidences indicate that the Baltica Craton and India linkage can be stable for at least ∼370 Ma (∼1770-1400 Ma). There is also reasonable evidence in support of India-North China Craton spatial proximity at ∼1770 Ma.

Urban inoculation and the decline of smallpox mortality in eighteenth-century cities-a reply to Razzell.

PubMed

Davenport, Romola J; Boulton, Jeremy; Schwarz, Leonard

2016-02-01

Smallpox was probably the single most lethal disease in eighteenth-century Britain but was reduced to a minor cause of death by the mid-nineteenth century due to vaccination programmes post-1798. While the success of vaccination is unquestionable, it remains disputed to what extent the prophylactic precursor of vaccination, inoculation, reduced smallpox mortality in the eighteenth century. Smallpox was most lethal in urban populations, but most researchers have judged inoculation to have been unpopular in large towns. Recently, however, Razzell argued that inoculation significantly reduced smallpox mortality of adults and older children in London in the last third of the eighteenth century. This article uses demographic evidence from London and Manchester to confirm previous findings of a sudden fall in adult smallpox mortality and a rise in the importance of smallpox in early childhood c . 1770. The nature of these changes is consistent with an increase in smallpox transmission in London and Manchester after 1770 and indicates that smallpox inoculation was insufficient to reduce smallpox mortality in large towns. It remains unclear whether inoculation could have operated to enhance smallpox transmission or whether changes in the properties of the smallpox virus drove the intensification of smallpox mortality among young children post-1770.

Possible Cause of Extremely Bright Aurora Witnessed in East Asia on 17 September 1770

NASA Astrophysics Data System (ADS)

Ebihara, Yusuke; Hayakawa, Hisashi; Iwahashi, Kiyomi; Tamazawa, Harufumi; Kawamura, Akito Davis; Isobe, Hiroaki

2017-10-01

Extremely bright aurora was witnessed in East Asia on 17 September 1770, according to historical documents. The aurora was described as "as bright as a night with full moon" at magnetic latitude of 25°. The aurora was dominated by red color extending from near the horizon up beyond the polar star (corresponding to elevation angle of 35°). We performed a two-stream electron transport code to calculate the volume emission rates at 557.7 nm (OI) and 630.0 nm (OI). Two types of distribution of precipitating electrons were assumed. The first one is based on the unusually intense electron flux measured by the DMSP satellite in the March 1989 storm. The distribution consists of hot (peaking at 3 keV) and cold (peaking at 71 eV) components. The second one is the same as the first one, but the hot component is removed. We call this high-intensity low-energy electrons (HILEEs). The first spectrum results in an auroral display with a bright, lower green border. The second one results in red-dominated aurora extending up to the elevation angle of 35° when the equatorward boundary of the electron precipitation is located at 32° invariant latitude. The poleward boundary of the precipitation would be 42° invariant latitude or greater to explain the auroral display extending from near the horizon. The origin of the HILEEs is probably the plasma sheet or the plasmasphere that is transported earthward to L 1.39 due to enhanced magnetospheric convection. Local heating or acceleration is also plausible.

7 CFR 1770.25 - Unusual items and contingent liabilities.

Code of Federal Regulations, 2010 CFR

2010-01-01

... SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) ACCOUNTING REQUIREMENTS FOR RUS TELECOMMUNICATIONS... be measured in relation to the summary account level used for reporting purposes for Class A...

7 CFR 1770.17 - Expense matrix.

Code of Federal Regulations, 2010 CFR

2010-01-01

... compensation required by law; (4) Life, hospital, medical, dental, and vision plan insurance, and (5) Social... does not include payments for capital leases. (2) This subsidiary record category is applicable only to...

7 CFR 1770.17 - Expense matrix.

Code of Federal Regulations, 2011 CFR

2011-01-01

... compensation required by law; (4) Life, hospital, medical, dental, and vision plan insurance, and (5) Social... does not include payments for capital leases. (2) This subsidiary record category is applicable only to...

Finding Long Lost Lexell's Comet: The Fate of the First Discovered Near-Earth Object

NASA Astrophysics Data System (ADS)

Ye, Quan-Zhi; Wiegert, Paul A.; Hui, Man-To

2018-04-01

Jupiter-family Comet D/1770 L1 (Lexell) was the first discovered Near-Earth Object (NEO) and passed the Earth on 1770 July 1 at a recorded distance of 0.015 au. The comet was subsequently lost due to unfavorable observing circumstances during its next apparition followed by a close encounter with Jupiter in 1779. Since then, the fate of D/Lexell has attracted interest from the scientific community, and now we revisit this long-standing question. We investigate the dynamical evolution of D/Lexell based on a set of orbits recalculated using the observations made by Charles Messier, the comet’s discoverer, and find that there is a 98% chance that D/Lexell remains in the solar system by the year of 2000. This finding remains valid even if a moderate non-gravitational effect is imposed. Messier’s observations also suggest that the comet is one of the largest known near-Earth comets, with a nucleus of ≳10 km in diameter. This implies that the comet should have been detected by contemporary NEO surveys regardless of its activity level if it has remained in the inner solar system. We identify asteroid 2010 JL33 as a possible descendant of D/Lexell, with a 0.8% probability of chance alignment, but a direct orbital linkage of the two bodies has not been successfully accomplished. We also use the recalculated orbit to investigate the meteors potentially originating from D/Lexell. While no associated meteors have been unambiguously detected, we show that meteor observations can be used to better constrain the orbit of D/Lexell despite the comet being long lost.

Family history of alcoholism interacts with alcohol to affect brain regions involved in behavioral inhibition.

PubMed

Kareken, David A; Dzemidzic, Mario; Wetherill, Leah; Eiler, William; Oberlin, Brandon G; Harezlak, Jaroslaw; Wang, Yang; O'Connor, Sean J

2013-07-01

Impulsive behavior is associated with both alcohol use disorders and a family history of alcoholism (FHA). One operational definition of impulsive behavior is the stop-signal task (SST) which measures the time needed to stop a ballistic hand movement. Employ functional magnetic resonance imaging (fMRI) to study right frontal responses to stop signals in heavy drinking subjects with and without FHA, and as a function of alcohol exposure. Twenty-two family history-positive (FHP; age = 22.7 years, SD = 1.9) and 18 family history-negative (FHN; age = 23.7, SD = 1.8) subjects performed the SST in fMRI in two randomized visits: once during intravenous infusion of alcohol, clamped at a steady-state breath alcohol (BrAC) concentration of 60 mg/dL, and once during infusion of placebo saline. An independent reference group (n = 13, age = 23.7, SD = 1.8) was used to identify a priori right prefrontal regions activated by successful inhibition (Inh) trials, relative to "Go" trials that carried no need for inhibition [Inh > Go]. FHA interacted with alcohol exposure in right prefrontal cortex, where alcohol reduced [Inh > Go] activation in FHN subjects but not in FHP subjects. Within this right frontal cortical region, stop-signal reaction time also correlated negatively with [Inh > Go] activation, suggesting that the [Inh > Go] activity was related to inhibitory behavior. The results are consistent with the low level of response theory (Schuckit, J Stud Alcohol 55:149-158, 1980; Quinn and Fromme, Alcohol Clin Exp Res 35:1759-1770, 2011), with FHP being less sensitive to alcohol's effects.

Botetourt County road orders 1770-1778.

DOT National Transportation Integrated Search

2007-01-01

The road history projects undertaken by the Virginia Transportation Research Council establish the feasibility of studies of early road networks and their use in the environmental review process. These projects, by gathering and publishing the early ...

SECTION BB, FLOOR PLAN Dyess Air Force Base, Atlas ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

SECTION B-B, FLOOR PLAN - Dyess Air Force Base, Atlas F Missle Site S-8, Launch Facility, Approximately 3 miles east of Winters, 500 feet southwest of Highway 1770, center of complex, Winters, Runnels County, TX

Injury rates in Shotokan karate

PubMed Central

Critchley, G. R.; Mannion, S.; Meredith, C.

1999-01-01

OBJECTIVE: To document the injury rate in three British Shotokan karate championships in consecutive years. In these tournaments strict rules governed contact, with only "light" or "touch" contact allowed. Protective padding for the head, hands, or feet was prohibited. METHODS: Prospective recording of injuries resulting from 1770 bouts in three national competitions of 1996, 1997, and 1998. Details of ages and years of karate experience were also obtained. RESULTS: 160 injuries were sustained in 1770 bouts. The overall rate of injury was 0.09 per bout and 0.13 per competitor. 91 (57%) injuries were to the head. The average age of those injured was 22 years, with an average of nine years of experience in karate. CONCLUSIONS: The absence of protective padding does not result in higher injury rates than in most other series of Shotokan karate injuries. Strict refereeing is essential, however, to maintain control and minimise contact. 


 PMID:10378069

Health care utilization and costs associated with adherence to clinical practice guidelines for early magnetic resonance imaging among workers with acute occupational low back pain.

PubMed

Graves, Janessa M; Fulton-Kehoe, Deborah; Jarvik, Jeffrey G; Franklin, Gary M

2014-04-01

To estimate health care utilization and costs associated with adherence to clinical practice guidelines for the use of early magnetic resonance imaging (MRI; within the first 6 weeks of injury) for acute occupational low back pain (LBP). Washington State Disability Risk Identification Study Cohort (D-RISC), consisting of administrative claims and patient interview data from workers' compensation claimants (2002-2004). In this prospective, population-based cohort study, we compared health care utilization and costs among workers whose imaging was adherent to guidelines (no early MRI) to workers whose imaging was not adherent to guidelines (early MRI in the absence of red flags). We identified workers (age>18) with work-related LBP using administrative claims. We obtained demographic, injury, health, and employment information through telephone interviews to adjust for baseline differences between groups. We ascertained health care utilization and costs from administrative claims for 1 year following injury. Of 1,770 workers, 336 (19.0 percent) were classified as nonadherent to guidelines. Outpatient and physical/occupational therapy utilization was 52-54 percent higher for workers whose imaging was not adherent to guidelines compared to workers with guideline-adherent imaging; utilization of chiropractic care was significantly lower (18 percent). Nonadherence to guidelines for early MRI was associated with increased likelihood of lumbosacral injections or surgery and higher costs for out-patient, inpatient, and nonmedical services, and disability compensation. © Health Research and Educational Trust.

7 CFR 1770.26 - General.

Code of Federal Regulations, 2010 CFR

2010-01-01

... methods and principles of accounting prescribed by the state regulatory body having jurisdiction over the... telecommunications companies (47 CFR part 32), as those methods and principles of accounting are supplemented from... instruments by prescribing accounting principles, methodologies, and procedures applicable to all...

40 CFR 86.1770-99 - All-Electric Range Test requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... purpose of determining the energy efficiency and operating range of a ZEV or of a hybrid electric vehicle... hours. During this time, the vehicle's battery shall be charged to a full state-of-charge. (2) Driving...

40 CFR 86.1770-99 - All-Electric Range Test requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... purpose of determining the energy efficiency and operating range of a ZEV or of a hybrid electric vehicle... hours. During this time, the vehicle's battery shall be charged to a full state-of-charge. (2) Driving...

40 CFR 86.1770-99 - All-Electric Range Test requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... purpose of determining the energy efficiency and operating range of a ZEV or of a hybrid electric vehicle... hours. During this time, the vehicle's battery shall be charged to a full state-of-charge. (2) Driving...

40 CFR 86.1770-99 - All-Electric Range Test requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... purpose of determining the energy efficiency and operating range of a ZEV or of a hybrid electric vehicle... hours. During this time, the vehicle's battery shall be charged to a full state-of-charge. (2) Driving...

B-Vitamin Levels in Human Milk among Different Lactation Stages and Areas in China

PubMed Central

Ren, Xiangnan; Yang, Zhenyu; Shao, Bing; Yin, Shi-an; Yang, Xiaoguang

2015-01-01

To determine the contents of B-vitamins in human milk in China, we analyzed 1778 human milk samples from the sample bank of the National High Technique R & D Program (863 Projects) which was a cross-sectional survey and covered 6419 human milk samples from healthy lactating mothers who were at different stages of lactation (0–330 days postpartum) in 11 provinces of China. The contents of free forms of six B-vitamins in these human milk samples were analyzed by using UPLC-MS/MS. The median concentrations of free form of 6 B-vitamins in colostrums, transitional milk, 15–180 d mature milk and 181-330 d mature milk were respectively as follows: thiamin 5.0 µg/L, 6.7 µg/L, 21.1 µg/L and 40.7 µg/L; riboflavin 29.3 µg/L, 40.6 µg/L, 33.6 µg/L and 29.6 µg/L; niacin 470.7 µg/L, 661.3 µg/L, 687.0 µg/L and 571.3 µg/L; vitamin B-6 4.6 µg/L, 16.1 µg/L, 62.7 µg/L and 80.7 µg/L; flavin adenine dinucleotide (FAD) 808.7 µg/L, 1162.8 µg/L, 1023.9 µg/L and 1057.2 µg/L; pantothenic acid 1770.9 µg/L, 2626.8 µg/L, 2213.0 µg/L and 1895.5 µg/L. The contents of 6 B-vitamins varied significantly among the different lactation stages and different areas (coastal area vs inland area, rural area vs urban area). The present study indicated that the concentrations of B-vitamins in colostrum were generally much lower than those in transitional milk and mature milk. Further studies are warranted for their roles and significance on B-vitamins in colostrum in nutrition and metabolism of neonates. PMID:26186707

B-Vitamin Levels in Human Milk among Different Lactation Stages and Areas in China.

PubMed

Ren, Xiangnan; Yang, Zhenyu; Shao, Bing; Yin, Shi-An; Yang, Xiaoguang

2015-01-01

To determine the contents of B-vitamins in human milk in China, we analyzed 1778 human milk samples from the sample bank of the National High Technique R & D Program (863 Projects) which was a cross-sectional survey and covered 6419 human milk samples from healthy lactating mothers who were at different stages of lactation (0-330 days postpartum) in 11 provinces of China. The contents of free forms of six B-vitamins in these human milk samples were analyzed by using UPLC-MS/MS. The median concentrations of free form of 6 B-vitamins in colostrums, transitional milk, 15-180 d mature milk and 181-330 d mature milk were respectively as follows: thiamin 5.0 µg/L, 6.7 µg/L, 21.1 µg/L and 40.7 µg/L; riboflavin 29.3 µg/L, 40.6 µg/L, 33.6 µg/L and 29.6 µg/L; niacin 470.7 µg/L, 661.3 µg/L, 687.0 µg/L and 571.3 µg/L; vitamin B-6 4.6 µg/L, 16.1 µg/L, 62.7 µg/L and 80.7 µg/L; flavin adenine dinucleotide (FAD) 808.7 µg/L, 1162.8 µg/L, 1023.9 µg/L and 1057.2 µg/L; pantothenic acid 1770.9 µg/L, 2626.8 µg/L, 2213.0 µg/L and 1895.5 µg/L. The contents of 6 B-vitamins varied significantly among the different lactation stages and different areas (coastal area vs inland area, rural area vs urban area). The present study indicated that the concentrations of B-vitamins in colostrum were generally much lower than those in transitional milk and mature milk. Further studies are warranted for their roles and significance on B-vitamins in colostrum in nutrition and metabolism of neonates.

42 CFR 52.8 - Other HHS regulations and policies that apply.

Code of Federal Regulations, 2010 CFR

2010-10-01

... (March 28, 1994)—NIH Guidelines on the Inclusion of Women and Minorities as Subjects in Clinical Research... on Women's Health, NIH, Room 201, Building 1, MSC 0161, BETHESDA, MD 20892-0161 (301-402-1770; not a...

7 CFR 1770.5 - Periods of retention.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., would have been expected to accomplish the desired result consistent with cost effectiveness... lowest reasonable cost consistent with cost effectiveness, reliability, safety, and expedition. (b... utility service, all removal and restoration activities are completed, and all costs are retired from the...

hi_dni_10km

Science.gov Websites

Microsoft Windows XP Version 5.1 (Build 2600) Service Pack 3; ESRI ArcCatalog 9.3.0.1770 en Monthly and @NREL.gov 10km Direct Normal Microsoft Windows XP Version 5.1 (Build 2600) Service Pack 3; ESRI ArcCatalog

Method for fabricating a microelectromechanical resonator

DOEpatents

Wojciechowski, Kenneth E; Olsson, III, Roy H

2013-02-05

A method is disclosed which calculates dimensions for a MEM resonator in terms of integer multiples of a grid width G for reticles used to fabricate the resonator, including an actual sub-width L.sub.a=NG and an effective electrode width W.sub.e=MG where N and M are integers which minimize a frequency error f.sub.e=f.sub.d-f.sub.a between a desired resonant frequency f.sub.d and an actual resonant frequency f.sub.a. The method can also be used to calculate an overall width W.sub.o for the MEM resonator, and an effective electrode length L.sub.e which provides a desired motional impedance for the MEM resonator. The MEM resonator can then be fabricated using these values for L.sub.a, W.sub.e, W.sub.o and L.sub.e. The method can also be applied to a number j of MEM resonators formed on a common substrate.

41 CFR 101-6.217 - Laws authorizing Federal financial assistance for programs to which this subpart applies.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Credit Union Act, 12 U.S.C. 1770). (j) Donation of surplus property to the American National Red Cross..., preserving and compiling, and publishing of documentary sources significant to the history of the United...

41 CFR 101-6.217 - Laws authorizing Federal financial assistance for programs to which this subpart applies.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Credit Union Act, 12 U.S.C. 1770). (j) Donation of surplus property to the American National Red Cross..., preserving and compiling, and publishing of documentary sources significant to the history of the United...

41 CFR 101-6.217 - Laws authorizing Federal financial assistance for programs to which this subpart applies.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Credit Union Act, 12 U.S.C. 1770). (j) Donation of surplus property to the American National Red Cross..., preserving and compiling, and publishing of documentary sources significant to the history of the United...

7 CFR 1770.4 - Record storage media.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF... the applicable retention period provided for in the master index of records, unless there is quality... must be verified for accuracy and documented. (b) Each borrower is required to implement internal...

40 CFR 52.1770 - Identification of plan.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Particulates from Mica or Feldspar Processing Plants 04/01/03 09/17/03, 68 FR 54362 Sect .0510 Particulates..., approving Paragraph (g) excluding the following language: “excluding startups, shutdowns, maintenance... facilities producing ethanol by natural fermentation under the North American Industry Classification System...

40 CFR 52.1770 - Identification of plan.

Code of Federal Regulations, 2014 CFR

2014-07-01

... .0509 Particulates from Mica or Feldspar Processing Plants 04/01/03 09/17/03, 68 FR 54362 Sect .0510... Paragraph (g). Also, approving Paragraph (g) excluding the following language: “excluding startups... production facilities producing ethanol by natural fermentation under the North American Industry...

40 CFR 52.1770 - Identification of plan.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Particulates from Mica or Feldspar Processing Plants 04/01/03 09/17/03, 68 FR 54362 Sect .0510 Particulates..., approving Paragraph (g) excluding the following language: “excluding startups, shutdowns, maintenance... facilities producing ethanol by natural fermentation under the North American Industry Classification System...

40 CFR 60.1770 - What must I do if any of my continuous emission monitoring systems are temporarily unavailable to...

Code of Federal Regulations, 2014 CFR

2014-07-01

... Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule-Continuous... alternate methods for collecting data when systems malfunction or when repairs, calibration checks, or zero...

40 CFR 60.1770 - What must I do if any of my continuous emission monitoring systems are temporarily unavailable to...

Code of Federal Regulations, 2012 CFR

2012-07-01

... Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule-Continuous... alternate methods for collecting data when systems malfunction or when repairs, calibration checks, or zero...

40 CFR 60.1770 - What must I do if any of my continuous emission monitoring systems are temporarily unavailable to...

Code of Federal Regulations, 2013 CFR

2013-07-01

... Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule-Continuous... alternate methods for collecting data when systems malfunction or when repairs, calibration checks, or zero...

7 CFR 1770.12 - Supplementary accounts.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AGRICULTURE (CONTINUED) ACCOUNTING REQUIREMENTS FOR RUS TELECOMMUNICATIONS BORROWERS Uniform System of... shall be changed to conform with the State's accounting system. (b) In addition to the accounts set... Uniform System of Accounts. In those instances in which a State regulatory body having jurisdiction over...

The late Little Ice Age landslide calamity in North Bohemia: Triggers, impacts and post-landslide development reconstructed from documentary data (case study of the Kozí vrch Hill landslide)

NASA Astrophysics Data System (ADS)

Raška, Pavel; Zábranský, Vilém; Brázdil, Rudolf; Lamková, Jana

2016-02-01

The beginning of the 1770s in the Czech Lands is well documented for its meteorological extremes and their social impacts. However, the effects of these extremes on geomorphic systems and on landslide occurrence and activity in particular have been minimally studied. In this paper, we use a complex set of written and iconographic documentary data to reconstruct the landslide calamity in North Bohemia, with a detailed case study of the Kozí vrch Hill landslide. The landslide calamity of 1770 is the oldest known landslide calamity in this region, including 14 documented events; and its reconstruction may therefore provide important data on landslide frequency, triggers, and impacts during the adverse weather patterns in the last part of the Little Ice Age (LIA). We focus on a case study of the Kozí vrch Hill landslide, and we use the documentary evidence and field techniques to reconstruct its location, extent, topography, kinematics, and triggers. Based on precipitation indices and weather descriptions, the extremely wet and rainy preceding year and the 1769/1770 winter were the major triggering factors that resulted in water saturation of Neogene volcaniclastics underlying the basalt lava flows and their subsequent collapse. Furthermore, we analyse the post-landslide terrain transformation and land use patterns during the 240 years following the landslide to illustrate the persistence of particular landslide features. We conclude that the major transformations, which obscured most of the landslide features, occurred in only the last 50-60 years. Finally, we discuss the role of documentary data and the current methodological advances in their use for the reconstruction of landslide frequency and impacts during the LIA.

12 CFR 1770.4 - Submission requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... organizational chart when changes occur affecting the status of executive officers under this part; (8) Proxy...) When an Enterprise makes any changes to the termination provisions of any compensation or benefit... the following materials: (1) The details of the agreement or program change, e.g., employment...

Health Care Utilization and Costs Associated with Adherence to Clinical Practice Guidelines for Early Magnetic Resonance Imaging among Workers with Acute Occupational Low Back Pain

PubMed Central

Graves, Janessa M; Fulton-Kehoe, Deborah; Jarvik, Jeffrey G; Franklin, Gary M

2014-01-01

Objective To estimate health care utilization and costs associated with adherence to clinical practice guidelines for the use of early magnetic resonance imaging (MRI; within the first 6 weeks of injury) for acute occupational low back pain (LBP). Data Sources Washington State Disability Risk Identification Study Cohort (D-RISC), consisting of administrative claims and patient interview data from workers’ compensation claimants (2002–2004). Study Design In this prospective, population-based cohort study, we compared health care utilization and costs among workers whose imaging was adherent to guidelines (no early MRI) to workers whose imaging was not adherent to guidelines (early MRI in the absence of red flags). Data Collection/Extraction Methods We identified workers (age >18) with work-related LBP using administrative claims. We obtained demographic, injury, health, and employment information through telephone interviews to adjust for baseline differences between groups. We ascertained health care utilization and costs from administrative claims for 1 year following injury. Principal Findings Of 1,770 workers, 336 (19.0 percent) were classified as nonadherent to guidelines. Outpatient and physical/occupational therapy utilization was 52–54 percent higher for workers whose imaging was not adherent to guidelines compared to workers with guideline-adherent imaging; utilization of chiropractic care was significantly lower (18 percent). Conclusions Nonadherence to guidelines for early MRI was associated with increased likelihood of lumbosacral injections or surgery and higher costs for out-patient, inpatient, and nonmedical services, and disability compensation. PMID:23910019

12 CFR 1770.1 - Authority and scope.

Code of Federal Regulations, 2010 CFR

2010-01-01

... used for comparison purposes include publicly held financial institutions or major financial services... Housing Enterprises Financial Safety and Soundness Act of 1992 (“the Act”) (12 U.S.C. 4501 et seq... benefits that are comparable to benefits provided by other public or private entities involved in financial...

2009 Human Factors and Roadway Safety Workshop : Teen Driver Safety [SD .WMV (720x480/29fps/177.0 MB)

DOT National Transportation Integrated Search

2009-11-05

Iowa Department of Transportation Research and Technology Bureau video presentation from the 2009 human factors and roadway safety workshop session titled: Teen Driver Safety : Keynote Speaker Dan McGehee, director, Human Factors & Vehicle Safety Res...

75 FR 3273 - Request for OMB Clearance of an Information Collection Renewal

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-20

... 60012) Docket DOT-OST-2009-0294. The collection is in regards to the Disadvantaged Business Enterprise... information requested: Respondents: Certified Disadvantaged Business Enterprises (DBEs) that are pursuing, in... assist with $20 million is approximately 1,770. Form: U.S. Disadvantaged Business Enterprise (DBE...

Hydrologic conditions at the Idaho National Engineering Laboratory, 1982 to 1985

USGS Publications Warehouse

Pittman, J.R.; Fischer, P.R.; Jensen, R.G.

1988-01-01

Aqueous chemical and radioactive wastes discharged since 1952 to unlined ponds and wells at the INEL (Idaho National Engineering Laboratory) have affected water quality in perched groundwater zones and in the Snake River Plain Aquifer. Routine waste water disposal was changed from deep injection wells to ponds at the ICPP (Idaho Chemical Processing Plant) in 1984. During 1982-85, tritium concentrations increased in perched groundwater zones under disposal ponds, but cobalt-60 concentrations decreased. In 1985, perched groundwater under TRA disposal ponds contained up to 1,770 +or-30 pCi/mL (picocuries/milliliter) of tritium and 0.36+or-0.05 pCi/mL of cobalt-60. During 1982-85, tritium concentrations in water in the Snake River Plain aquifer decreased as much as 80 pCi/mL near the ICPP. In 1985, measurable tritium concentrations ranged from 0.9+or-0.3 to 93.4 +or-2.0 pCi/mL. Tritium was detected in groundwater near the southern boundary of the INEL, 9 miles south of the ICPP and TRA. Strontium-90 concentrations in groundwater, up to 63 +or-5 pCi/L (picocuries per liter) near the ICPP, generally were smaller than 1981 concentrations. Cesium-137 concentrations in groundwater near the ICPP ranged from 125 +or-14 to 237 +or-45 pCi/L. Maximum concentrations of plutonium-238 and plutonium-239 , -240 (undivided) were 1.31 +or-.0019 pCi/ml and 1.9 +or-0.00003 pCi/L. Sodium and chloride generally decreased during 1982-85. Nitrate concentrations increased near the TRA and NRF (Naval Reactors Facility) and decreased near the ICPP. (USGS)

7 CFR 1770.16 - Supplementary accounts required of nonprofit organizations.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Capital Stock. 1350.2 1350.2 Subscriptions to Memberships. 1350.3 1350.3 Subscriptions to Members' Equity.... 4130.2 4130.2 Other Current Liabilities—Miscellaneous. Long-Term Debt 4270.1 4270.1 Members' Redeemable Equity Certificates Subscribed but Unissued. 4270.2 4270.2 Members' Redeemable Equity Certificates Issued...

7 CFR 1770.16 - Supplementary accounts required of nonprofit organizations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Capital Stock. 1350.2 1350.2 Subscriptions to Memberships. 1350.3 1350.3 Subscriptions to Members' Equity.... 4130.2 4130.2 Other Current Liabilities—Miscellaneous. Long-Term Debt 4270.1 4270.1 Members' Redeemable Equity Certificates Subscribed but Unissued. 4270.2 4270.2 Members' Redeemable Equity Certificates Issued...

7 CFR 1770.16 - Supplementary accounts required of nonprofit organizations.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Capital Stock. 1350.2 1350.2 Subscriptions to Memberships. 1350.3 1350.3 Subscriptions to Members' Equity.... 4130.2 4130.2 Other Current Liabilities—Miscellaneous. Long-Term Debt 4270.1 4270.1 Members' Redeemable Equity Certificates Subscribed but Unissued. 4270.2 4270.2 Members' Redeemable Equity Certificates Issued...

AXONOMETRIC, LAUNCH DOOR AND DOOR CYLINDER, LAUNCH PLATFORM ROLLER GUIDE, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

AXONOMETRIC, LAUNCH DOOR AND DOOR CYLINDER, LAUNCH PLATFORM ROLLER GUIDE, CRIB SUSPENSION SHOCK STRUT, LAUNCH PLATFORM - Dyess Air Force Base, Atlas F Missle Site S-8, Launch Facility, Approximately 3 miles east of Winters, 500 feet southwest of Highway 1770, center of complex, Winters, Runnels County, TX

An Investigation of the Eighteenth-Century Achromatic Telescope

ERIC Educational Resources Information Center

Jaecks, Duane H.

2010-01-01

The optical quality and properties of over 200 telescopes residing in museums and private collections have been measured and tested with the goal of obtaining new information about the early development of the achromatic lens (1757-1770). Quantitative measurements of the chromatic and spherical aberration of telescope objective lenses were made…

7 CFR 1770.15 - Supplementary accounts required of all borrowers.

Code of Federal Regulations, 2013 CFR

2013-01-01

...—Classified This account shall include the original cost of the property capitalized in Accounts 2110 through... costs. This account shall also include the original cost of earth stations and spare parts, materials... include the original cost of radio equipment used to provide radio communication channels. Radio equipment...

7 CFR 1770.15 - Supplementary accounts required of all borrowers.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Switching—Circuit. 2212.2 2212.2 Digital Electronic Switching—Packet. 2230.11 Central Office Transmission... Retirement Work in Progress. Current Liabilities 2232.1 2232.1 Circuit Equipment—Electronic. 2232.2 2232.2... Expense—Circuit. 6212.2 6212.2 Digital Electronic Switching Expense—Packet. 6230.11 Radio Systems Expense...

7 CFR 1770.15 - Supplementary accounts required of all borrowers.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Switching—Circuit. 2212.2 2212.2 Digital Electronic Switching—Packet. 2230.11 Central Office Transmission... Retirement Work in Progress. Current Liabilities 2232.1 2232.1 Circuit Equipment—Electronic. 2232.2 2232.2... Expense—Circuit. 6212.2 6212.2 Digital Electronic Switching Expense—Packet. 6230.11 Radio Systems Expense...

7 CFR 1770.15 - Supplementary accounts required of all borrowers.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Switching—Circuit. 2212.2 2212.2 Digital Electronic Switching—Packet. 2230.11 Central Office Transmission... Retirement Work in Progress. Current Liabilities 2232.1 2232.1 Circuit Equipment—Electronic. 2232.2 2232.2... Expense—Circuit. 6212.2 6212.2 Digital Electronic Switching Expense—Packet. 6230.11 Radio Systems Expense...

INTERIOR VIEW, PASSAGE AND DOOR LETTING ONTO THE SOUTHEAST BED ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

INTERIOR VIEW, PASSAGE AND DOOR LETTING ONTO THE SOUTHEAST BED CHAMBER. THE ANGLED PASSAGE RUNS PARALLEL TO WHAT WAS AN EXTERIOR WALL OF THE THREE-SIDED WINDOW BOW PRESENT IN THE HOUSE’S ORIGINAL CA. 1770 STATE - The Woodlands, 4000 Woodlands Avenue, Philadelphia, Philadelphia County, PA

The Evolution of Structural Order as a Measure of Thermal History of Coke in the Blast Furnace

NASA Astrophysics Data System (ADS)

Lundgren, Maria; Khanna, Rita; Ökvist, Lena Sundqvist; Sahajwalla, Veena; Björkman, Bo

2014-04-01

Investigations were carried out on cokes heat treated in the laboratory and on cokes extracted from the experimental blast furnace (EBF) raceway and hearth. X-ray diffraction (XRD) measurements were performed to investigate changes in structural order ( L c), chemical transformations in coke ash along with comparative thermodynamic equilibrium studies and the influence of melt. Three data processing approaches were used to compute L c values as a function of temperature and time and linear correlations were established between L c and heat treatment temperatures during laboratory investigations. These were used to estimate temperatures experienced by coke in various regions of EBF and estimated raceway temperatures were seen to follow the profile of combustion peak. The MgAl2O4 spinel was observed in coke submerged in slag during laboratory studies and in cokes found further into the raceway. Coke in contact with hot metal showed XRD peaks corresponding to presence of Fe3Si. The intensity of SiO2 peak in coke ash was seen to decrease with increasing temperature and disappeared at around 1770 K (1500 °C) due to the formation of SiC. This study has shown that the evolution of structural order and chemical transformations in coke could be used to estimate its thermal history in blast furnaces.

Sub-natural width resonances in Cs vapor confined in micrometric thickness optical cell

NASA Astrophysics Data System (ADS)

Cartaleva, S.; Krasteva, A.; Sargsyan, A.; Sarkisyan, D.; Slavov, D.; Vartanyan, T.

2013-03-01

We present here the behavior of Electromagnetically Induced Transparency (EIT), Velocity Selective Optical Pumping (VSOP) resonances and Velocity Selective Excitation (VSE) resonances observed in Cs vapor confined in а micrometric optical cell (MC) with thickness L = 6λ, λ = 852nm. For comparison of behavior of VSE resonance another conventional optical cell with thickness L=2.5 cm is used. Cells are irradiated in orthogonal to their windows directions by probe beam scanned on the Fg = 4 → Fe= 3, 4, 5 set of transitions and pump beam fixed at the Fg = 3 → Fe = 4 transition, on the D2 line of Cs. The enhanced absorption (fluorescence) narrow VSOP resonance at the closed transition transforms into reduced absorption (fluorescence) one with small increase of atomic concentration or light intensity. A striking difference appears between the VSE resonance broadening in L = 6λ and conventional L = 2.5cm cells.

Orbital-plane precessional resonances for binary black-hole systems

NASA Astrophysics Data System (ADS)

Kesden, Michael; Zhao, Xinyu; Gerosa, Davide

2016-03-01

We derive a new class of post-Newtonian precessional resonances for binary black holes (BBHs) with misaligned spins. According to the orbit-averaged spin-precession equations, the angle between the orbital angular momentum L and the total angular momentum J oscillates with a period τ during which time L precesses about J by an angle α. If α is a rational multiple of 2 π, the precession of L will be closed indicating a resonance between the polar and azimuthal evolution of L . If α is an integer multiple of 2 π, the misalignment between the angular momentum ΔL radiated over the period τ and J will be minimized, as will the opening angle of the cone about which J precesses in an inertial frame. However, the direction of ΔL will remain nearly fixed in an inertial frame over many precessional periods, causing the direction of J to tilt as inspiraling BBHs pass through such a resonance. Generic BBHs encounter many such resonances during an inspiral from large separations. We derive the evolution of J near a resonance and assess their detectability by gravitational-wave detectors and astrophysical implications.

40 CFR 52.1770 - Identification of plan.

Code of Federal Regulations, 2010 CFR

2010-07-01

... FR 61213 Sect .0507 Particulates from Chemical Fertilizer Manufacturing Plants 04/01/03 09/17/03, 68... Organic Compounds Sect .0901 Definitions 07/01/96 08/01/97, 62 FR 41277 Sect .0902 Applicability 07/01/00... FR 61213 Repealed. Sect .0939 Determination of Volatile Organic Compounds Emissions 07/01/88 01/16/90...

40 CFR 52.1770 - Identification of plan.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 61213 Sect .0515 Particulates from Miscellaneous Industrial Processes 04/01/03 09/17/03, 68 FR 54362... Utility Boilers 08/01/91 02/14/96, 61 FR 5689 Sect .0540 Particulates from Fugitive Non-process Dust... Sect .0955 Thread Bonding Manufacturing 04/01/95 02/01/96, 62 FR 3589 Sect .0956 Glass Christmas...

38 CFR 17.71 - Revocation of VA approval.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Community Residential Care § 17.71 Revocation of VA approval. (a) If a hearing official determines under § 17.70 of this part that a community residential care facility does not comply with the standards set forth in § 17.63 of this part and determines that the community residential care facility shall not have...

7 CFR 1770.15 - Supplementary accounts required of all borrowers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... process of manufacture for supply stock. Transportation charges and sales and use taxes, as far as.... Transportation and sales and use taxes which are not included as part of the cost of particular material shall be... transportation charges, sales and use taxes, and cash and other purchase discounts. Inventory shortages and...

Calcium orthophosphates and human beings

PubMed Central

Dorozhkin, Sergey V.

2012-01-01

The historical development of a scientific knowledge on calcium orthophosphates from the 1770s until 1940 is described. Many forgotten and poorly known historical facts and approaches have been extracted from old publications and then they have been analyzed, systematized and reconsidered from the modern point of view. The chosen time scale starts with the earliest available studies of 1770s (to the best of my findings, calcium orthophosphates had been unknown before), passes through the entire 19th century and finishes in 1940, because since then the amount of publications on calcium orthophosphates rapidly increases and the subject becomes too broad. Furthermore, since publications of the second half of the 20th century are easily accessible, a substantial amount of them have already been reviewed by other researchers. The reported historical findings clearly demonstrate that the substantial amount of the scientific facts and experimental approaches have been known for very many decades and, in fact, the considerable quantity of relatively recent investigations on calcium orthophosphates is just either a further development of the earlier studies or a rediscovery of the already forgotten knowledge. PMID:23507803

Acute necrotising pancreatitis derived from low-dose corticosteroid use: an important reminder of clinical management

PubMed Central

Sabre, Alexander; Guthrie, Morgan Mary; Maleknia, Reza

2015-01-01

Although the exact mechanism is unknown, incidence of drug-induced pancreatitis from corticosteroids is well established in the medical literature. Commonly reported in chronic steroid-dependent individuals who require large doses for a wide array of pathologies, the incidence of damage to the pancreas from low-doses have not been well described. We report a case of a 68-year-old woman who presented with severe abdominal pain, nausea and vomiting, 3 days after the initiation of low-dose methylprednisolone for osteoarthritis. Inpatient laboratory analysis revealed an elevated lipase of 1770 U/L and CT scan showing extensive necrotising pancreatitis involving the head, body and tail. Cessation of the causative medication and conservative treatment successfully led to resolution of symptoms. We present this case to inform clinicians of the precipitance of pancreatitis from modest strength corticosteroid management, so that more accurate and improved performance in pharmacological decisions can be made for patient care. PMID:26150628

Acute necrotising pancreatitis derived from low-dose corticosteroid use: an important reminder of clinical management.

PubMed

Sabre, Alexander; Guthrie, Morgan Mary; Maleknia, Reza

2015-07-06

Although the exact mechanism is unknown, incidence of drug-induced pancreatitis from corticosteroids is well established in the medical literature. Commonly reported in chronic steroid-dependent individuals who require large doses for a wide array of pathologies, the incidence of damage to the pancreas from low-doses have not been well described. We report a case of a 68-year-old woman who presented with severe abdominal pain, nausea and vomiting, 3 days after the initiation of low-dose methylprednisolone for osteoarthritis. Inpatient laboratory analysis revealed an elevated lipase of 1770 U/L and CT scan showing extensive necrotising pancreatitis involving the head, body and tail. Cessation of the causative medication and conservative treatment successfully led to resolution of symptoms. We present this case to inform clinicians of the precipitance of pancreatitis from modest strength corticosteroid management, so that more accurate and improved performance in pharmacological decisions can be made for patient care. 2015 BMJ Publishing Group Ltd.

Ammonia removal in food waste anaerobic digestion using a side-stream stripping process.

PubMed

Serna-Maza, A; Heaven, S; Banks, C J

2014-01-01

Three 35-L anaerobic digesters fed on source segregated food waste were coupled to side-stream ammonia stripping columns and operated semi-continuously over 300 days, with results in terms of performance and stability compared to those of a control digester without stripping. Biogas was used as the stripping medium, and the columns were operated under different conditions of temperature (55, 70, 85 °C), pH (unadjusted and pH 10), and RT (2-5 days). To reduce digester TAN concentrations to a useful level a high temperature (≥70 °C) and a pH of 10 were needed; under these conditions 48% of the TAN was removed over a 138-day period without any detrimental effects on digester performance. Other effects of the stripping process were an overall reduction in digestate organic nitrogen-containing fraction compared to the control and a recovery in the acetoclastic pathway when TAN concentration was 1770±20 mg kg(-1). Copyright © 2013 Elsevier Ltd. All rights reserved.

Search for new phenomena in final states with two opposite-charge, same-flavor leptons, jets, and missing transverse momentum in pp collisions at $$ \\sqrt{s}=13 $$ TeV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sirunyan, A. M.; Tumasyan, A.; Adam, W.

Search results are presented for physics beyond the standard model in final states with two opposite-charge, same-flavor leptons, jets, and missing transverse momentum. The data sample corresponds to an integrated luminosity of 35.9 fb –1 of proton-proton collisions at √s = 13 TeV collected with the CMS detector at the LHC in 2016. The analysis uses the invariant mass of the lepton pair, searching for a kinematic edge or a resonant-like excess compatible with the Z boson mass. The search for a kinematic edge targets production of particles sensitive to the strong force, while the resonance search targets both stronglymore » and electroweakly produced new physics. The observed yields are consistent with the expectations from the standard model, and the results are interpreted in the context of simplified models of supersymmetry. In a gauge mediated supersymmetry breaking (GMSB) model of gluino pair production with decay chains including Z bosons, gluino masses up to 1500–1770 GeV are excluded at the 95% confidence level depending on the lightest neutralino mass. In a model of electroweak chargino-neutralino production, chargino masses as high as 610 GeV are excluded when the lightest neutralino is massless. In GMSB models of electroweak neutralino-neutralino production, neutralino masses up to 500-650 GeV are excluded depending on the decay mode assumed. Lastly, in a model with bottom squark pair production and decay chains resulting in a kinematic edge in the dilepton invariant mass distribution, bottom squark masses up to 980–1200 GeV are excluded depending on the mass of the next-to-lightest neutralino.« less

Search for new phenomena in final states with two opposite-charge, same-flavor leptons, jets, and missing transverse momentum in pp collisions at $$ \\sqrt{s}=13 $$ TeV

DOE PAGES

Sirunyan, A. M.; Tumasyan, A.; Adam, W.; ...

2018-03-13

Search results are presented for physics beyond the standard model in final states with two opposite-charge, same-flavor leptons, jets, and missing transverse momentum. The data sample corresponds to an integrated luminosity of 35.9 fb –1 of proton-proton collisions at √s = 13 TeV collected with the CMS detector at the LHC in 2016. The analysis uses the invariant mass of the lepton pair, searching for a kinematic edge or a resonant-like excess compatible with the Z boson mass. The search for a kinematic edge targets production of particles sensitive to the strong force, while the resonance search targets both stronglymore » and electroweakly produced new physics. The observed yields are consistent with the expectations from the standard model, and the results are interpreted in the context of simplified models of supersymmetry. In a gauge mediated supersymmetry breaking (GMSB) model of gluino pair production with decay chains including Z bosons, gluino masses up to 1500–1770 GeV are excluded at the 95% confidence level depending on the lightest neutralino mass. In a model of electroweak chargino-neutralino production, chargino masses as high as 610 GeV are excluded when the lightest neutralino is massless. In GMSB models of electroweak neutralino-neutralino production, neutralino masses up to 500-650 GeV are excluded depending on the decay mode assumed. Lastly, in a model with bottom squark pair production and decay chains resulting in a kinematic edge in the dilepton invariant mass distribution, bottom squark masses up to 980–1200 GeV are excluded depending on the mass of the next-to-lightest neutralino.« less

Search for new phenomena in final states with two opposite-charge, same-flavor leptons, jets, and missing transverse momentum in pp collisions at √{s}=13 TeV

NASA Astrophysics Data System (ADS)

Sirunyan, A. M.; Tumasyan, A.; Adam, W.; Ambrogi, F.; Asilar, E.; Bergauer, T.; Brandstetter, J.; Brondolin, E.; Dragicevic, M.; Erö, J.; Flechl, M.; Friedl, M.; Frühwirth, R.; Ghete, V. M.; Grossmann, J.; Hrubec, J.; Jeitler, M.; König, A.; Krammer, N.; Krätschmer, I.; Liko, D.; Madlener, T.; Mikulec, I.; Pree, E.; Rabady, D.; Rad, N.; Rohringer, H.; Schieck, J.; Schöfbeck, R.; Spanring, M.; Spitzbart, D.; Waltenberger, W.; Wittmann, J.; Wulz, C.-E.; Zarucki, M.; Chekhovsky, V.; Mossolov, V.; Suarez Gonzalez, J.; De Wolf, E. A.; Di Croce, D.; Janssen, X.; Lauwers, J.; Van De Klundert, M.; Van Haevermaet, H.; Van Mechelen, P.; Van Remortel, N.; Abu Zeid, S.; Blekman, F.; D'Hondt, J.; De Bruyn, I.; De Clercq, J.; Deroover, K.; Flouris, G.; Lontkovskyi, D.; Lowette, S.; Moortgat, S.; Moreels, L.; Python, Q.; Skovpen, K.; Tavernier, S.; Van Doninck, W.; Van Mulders, P.; Van Parijs, I.; Brun, H.; Clerbaux, B.; De Lentdecker, G.; Delannoy, H.; Fasanella, G.; Favart, L.; Goldouzian, R.; Grebenyuk, A.; Karapostoli, G.; Lenzi, T.; Luetic, J.; Maerschalk, T.; Marinov, A.; Randle-conde, A.; Seva, T.; Vander Velde, C.; Vanlaer, P.; Vannerom, D.; Yonamine, R.; Zenoni, F.; Zhang, F.; Cimmino, A.; Cornelis, T.; Dobur, D.; Fagot, A.; Gul, M.; Khvastunov, I.; Poyraz, D.; Roskas, C.; Salva, S.; Tytgat, M.; Verbeke, W.; Zaganidis, N.; Bakhshiansohi, H.; Bondu, O.; Brochet, S.; Bruno, G.; Caputo, C.; Caudron, A.; De Visscher, S.; Delaere, C.; Delcourt, M.; Francois, B.; Giammanco, A.; Jafari, A.; Komm, M.; Krintiras, G.; Lemaitre, V.; Magitteri, A.; Mertens, A.; Musich, M.; Piotrzkowski, K.; Quertenmont, L.; Vidal Marono, M.; Wertz, S.; Beliy, N.; Aldá Júnior, W. L.; Alves, F. L.; Alves, G. A.; Brito, L.; Correa Martins Junior, M.; Hensel, C.; Moraes, A.; Pol, M. E.; Rebello Teles, P.; Belchior Batista Das Chagas, E.; Carvalho, W.; Chinellato, J.; Custódio, A.; Da Costa, E. M.; Da Silveira, G. G.; De Jesus Damiao, D.; Fonseca De Souza, S.; Huertas Guativa, L. M.; Malbouisson, H.; Melo De Almeida, M.; Mora Herrera, C.; Mundim, L.; Nogima, H.; Santoro, A.; Sznajder, A.; Tonelli Manganote, E. J.; Torres Da Silva De Araujo, F.; Vilela Pereira, A.; Ahuja, S.; Bernardes, C. A.; Fernandez Perez Tomei, T. R.; Gregores, E. M.; Mercadante, P. G.; Novaes, S. F.; Padula, Sandra S.; Romero Abad, D.; Ruiz Vargas, J. C.; Aleksandrov, A.; Hadjiiska, R.; Iaydjiev, P.; Misheva, M.; Rodozov, M.; Shopova, M.; Stoykova, S.; Sultanov, G.; Dimitrov, A.; Glushkov, I.; Litov, L.; Pavlov, B.; Petkov, P.; Fang, W.; Gao, X.; Ahmad, M.; Bian, J. G.; Chen, G. M.; Chen, H. S.; Chen, M.; Chen, Y.; Jiang, C. H.; Leggat, D.; Liao, H.; Liu, Z.; Romeo, F.; Shaheen, S. M.; Spiezia, A.; Tao, J.; Wang, C.; Wang, Z.; Yazgan, E.; Zhang, H.; Zhao, J.; Ban, Y.; Chen, G.; Li, Q.; Liu, S.; Mao, Y.; Qian, S. J.; Wang, D.; Xu, Z.; Avila, C.; Cabrera, A.; Chaparro Sierra, L. F.; Florez, C.; González Hernández, C. F.; Ruiz Alvarez, J. D.; Courbon, B.; Godinovic, N.; Lelas, D.; Puljak, I.; Ribeiro Cipriano, P. M.; Sculac, T.; Antunovic, Z.; Kovac, M.; Brigljevic, V.; Ferencek, D.; Kadija, K.; Mesic, B.; Starodumov, A.; Susa, T.; Ather, M. W.; Attikis, A.; Mavromanolakis, G.; Mousa, J.; Nicolaou, C.; Ptochos, F.; Razis, P. A.; Rykaczewski, H.; Finger, M.; Finger, M.; Carrera Jarrin, E.; Ellithi Kamel, A.; Khalil, S.; Mohamed, A.; Dewanjee, R. K.; Kadastik, M.; Perrini, L.; Raidal, M.; Tiko, A.; Veelken, C.; Eerola, P.; Pekkanen, J.; Voutilainen, M.; Härkönen, J.; Järvinen, T.; Karimäki, V.; Kinnunen, R.; Lampén, T.; Lassila-Perini, K.; Lehti, S.; Lindén, T.; Luukka, P.; Tuominen, E.; Tuominiemi, J.; Tuovinen, E.; Talvitie, J.; Tuuva, T.; Besancon, M.; Couderc, F.; Dejardin, M.; Denegri, D.; Faure, J. L.; Ferri, F.; Ganjour, S.; Ghosh, S.; Givernaud, A.; Gras, P.; Hamel de Monchenault, G.; Jarry, P.; Kucher, I.; Locci, E.; Machet, M.; Malcles, J.; Negro, G.; Rander, J.; Rosowsky, A.; Sahin, M. Ö.; Titov, M.; Abdulsalam, A.; Antropov, I.; Baffioni, S.; Beaudette, F.; Busson, P.; Cadamuro, L.; Charlot, C.; Granier de Cassagnac, R.; Jo, M.; Lisniak, S.; Lobanov, A.; Martin Blanco, J.; Nguyen, M.; Ochando, C.; Ortona, G.; Paganini, P.; Pigard, P.; Regnard, S.; Salerno, R.; Sauvan, J. B.; Sirois, Y.; Stahl Leiton, A. G.; Strebler, T.; Yilmaz, Y.; Zabi, A.; Zghiche, A.; Agram, J.-L.; Andrea, J.; Bloch, D.; Brom, J.-M.; Buttignol, M.; Chabert, E. C.; Chanon, N.; Collard, C.; Conte, E.; Coubez, X.; Fontaine, J.-C.; Gelé, D.; Goerlach, U.; Jansová, M.; Le Bihan, A.-C.; Tonon, N.; Van Hove, P.; Gadrat, S.; Beauceron, S.; Bernet, C.; Boudoul, G.; Chierici, R.; Contardo, D.; Depasse, P.; El Mamouni, H.; Fay, J.; Finco, L.; Gascon, S.; Gouzevitch, M.; Grenier, G.; Ille, B.; Lagarde, F.; Laktineh, I. B.; Lethuillier, M.; Mirabito, L.; Pequegnot, A. L.; Perries, S.; Popov, A.; Sordini, V.; Vander Donckt, M.; Viret, S.; Toriashvili, T.; Rurua, L.; Autermann, C.; Beranek, S.; Feld, L.; Kiesel, M. 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S.; Lee, J.; Lee, S.; Lee, S. W.; Moon, C. S.; Oh, Y. D.; Sekmen, S.; Son, D. C.; Yang, Y. C.; Lee, A.; Kim, H.; Moon, D. H.; Oh, G.; Brochero Cifuentes, J. A.; Goh, J.; Kim, T. J.; Cho, S.; Choi, S.; Go, Y.; Gyun, D.; Ha, S.; Hong, B.; Jo, Y.; Kim, Y.; Lee, K.; Lee, K. S.; Lee, S.; Lim, J.; Park, S. K.; Roh, Y.; Almond, J.; Kim, J.; Kim, J. S.; Lee, H.; Lee, K.; Nam, K.; Oh, S. B.; Radburn-Smith, B. C.; Seo, S. h.; Yang, U. K.; Yoo, H. D.; Yu, G. B.; Choi, M.; Kim, H.; Kim, J. H.; Lee, J. S. H.; Park, I. C.; Choi, Y.; Hwang, C.; Lee, J.; Yu, I.; Dudenas, V.; Juodagalvis, A.; Vaitkus, J.; Ahmed, I.; Ibrahim, Z. A.; Md Ali, M. A. B.; Mohamad Idris, F.; Wan Abdullah, W. A. T.; Yusli, M. N.; Zolkapli, Z.; Reyes-Almanza, R.; Ramirez-Sanchez, G.; Duran-Osuna, M. C.; Castilla-Valdez, H.; De La Cruz-Burelo, E.; Heredia-De La Cruz, I.; Rabadan-Trejo, R. 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P.; Flix, J.; Fouz, M. C.; Garcia-Abia, P.; Gonzalez Lopez, O.; Goy Lopez, S.; Hernandez, J. M.; Josa, M. I.; Pérez-Calero Yzquierdo, A.; Puerta Pelayo, J.; Quintario Olmeda, A.; Redondo, I.; Romero, L.; Soares, M. S.; Álvarez Fernández, A.; Albajar, C.; de Trocóniz, J. F.; Missiroli, M.; Moran, D.; Cuevas, J.; Erice, C.; Fernandez Menendez, J.; Gonzalez Caballero, I.; González Fernández, J. R.; Palencia Cortezon, E.; Sanchez Cruz, S.; Suárez Andrés, I.; Vischia, P.; Vizan Garcia, J. M.; Cabrillo, I. J.; Calderon, A.; Chazin Quero, B.; Curras, E.; Duarte Campderros, J.; Fernandez, M.; Garcia-Ferrero, J.; Gomez, G.; Lopez Virto, A.; Marco, J.; Martinez Rivero, C.; Martinez Ruiz del Arbol, P.; Matorras, F.; Piedra Gomez, J.; Rodrigo, T.; Ruiz-Jimeno, A.; Scodellaro, L.; Trevisani, N.; Vila, I.; Vilar Cortabitarte, R.; Abbaneo, D.; Auffray, E.; Baillon, P.; Ball, A. H.; Barney, D.; Bianco, M.; Bloch, P.; Bocci, A.; Botta, C.; Camporesi, T.; Castello, R.; Cepeda, M.; Cerminara, G.; Chapon, E.; Chen, Y.; d'Enterria, D.; Dabrowski, A.; Daponte, V.; David, A.; De Gruttola, M.; De Roeck, A.; Dobson, M.; Dorney, B.; du Pree, T.; Dünser, M.; Dupont, N.; Elliott-Peisert, A.; Everaerts, P.; Fallavollita, F.; Franzoni, G.; Fulcher, J.; Funk, W.; Gigi, D.; Gill, K.; Glege, F.; Gulhan, D.; Harris, P.; Hegeman, J.; Innocente, V.; Janot, P.; Karacheban, O.; Kieseler, J.; Kirschenmann, H.; Knünz, V.; Kornmayer, A.; Kortelainen, M. J.; Krammer, M.; Lange, C.; Lecoq, P.; Lourenço, C.; Lucchini, M. T.; Malgeri, L.; Mannelli, M.; Martelli, A.; Meijers, F.; Merlin, J. A.; Mersi, S.; Meschi, E.; Milenovic, P.; Moortgat, F.; Mulders, M.; Neugebauer, H.; Orfanelli, S.; Orsini, L.; Pape, L.; Perez, E.; Peruzzi, M.; Petrilli, A.; Petrucciani, G.; Pfeiffer, A.; Pierini, M.; Racz, A.; Reis, T.; Rolandi, G.; Rovere, M.; Sakulin, H.; Schäfer, C.; Schwick, C.; Seidel, M.; Selvaggi, M.; Sharma, A.; Silva, P.; Sphicas, P.; Stakia, A.; Steggemann, J.; Stoye, M.; Tosi, M.; Treille, D.; Triossi, A.; Tsirou, A.; Veckalns, V.; Verweij, M.; Zeuner, W. D.; Bertl, W.; Caminada, L.; Deiters, K.; Erdmann, W.; Horisberger, R.; Ingram, Q.; Kaestli, H. C.; Kotlinski, D.; Langenegger, U.; Rohe, T.; Wiederkehr, S. A.; Bachmair, F.; Bäni, L.; Berger, P.; Bianchini, L.; Casal, B.; Dissertori, G.; Dittmar, M.; Donegà, M.; Grab, C.; Heidegger, C.; Hits, D.; Hoss, J.; Kasieczka, G.; Klijnsma, T.; Lustermann, W.; Mangano, B.; Marionneau, M.; Meinhard, M. T.; Meister, D.; Micheli, F.; Musella, P.; Nessi-Tedaldi, F.; Pandolfi, F.; Pata, J.; Pauss, F.; Perrin, G.; Perrozzi, L.; Quittnat, M.; Reichmann, M.; Schönenberger, M.; Shchutska, L.; Tavolaro, V. R.; Theofilatos, K.; Vesterbacka Olsson, M. L.; Wallny, R.; Zhu, D. H.; Aarrestad, T. K.; Amsler, C.; Canelli, M. F.; De Cosa, A.; Del Burgo, R.; Donato, S.; Galloni, C.; Hreus, T.; Kilminster, B.; Ngadiuba, J.; Pinna, D.; Rauco, G.; Robmann, P.; Salerno, D.; Seitz, C.; Takahashi, Y.; Zucchetta, A.; Candelise, V.; Doan, T. H.; Jain, Sh.; Khurana, R.; Kuo, C. M.; Lin, W.; Pozdnyakov, A.; Yu, S. S.; Kumar, Arun; Chang, P.; Chao, Y.; Chen, K. F.; Chen, P. H.; Fiori, F.; Hou, W.-S.; Hsiung, Y.; Liu, Y. F.; Lu, R.-S.; Paganis, E.; Psallidas, A.; Steen, A.; Tsai, J. f.; Asavapibhop, B.; Kovitanggoon, K.; Singh, G.; Srimanobhas, N.; Boran, F.; Cerci, S.; Damarseckin, S.; Demiroglu, Z. S.; Dozen, C.; Dumanoglu, I.; Girgis, S.; Gokbulut, G.; Guler, Y.; Hos, I.; Kangal, E. E.; Kara, O.; Kayis Topaksu, A.; Kiminsu, U.; Oglakci, M.; Onengut, G.; Ozdemir, K.; Sunar Cerci, D.; Tali, B.; Turkcapar, S.; Zorbakir, I. S.; Zorbilmez, C.; Bilin, B.; Karapinar, G.; Ocalan, K.; Yalvac, M.; Zeyrek, M.; Gülmez, E.; Kaya, M.; Kaya, O.; Tekten, S.; Yetkin, E. A.; Agaras, M. N.; Atay, S.; Cakir, A.; Cankocak, K.; Grynyov, B.; Levchuk, L.; Sorokin, P.; Aggleton, R.; Ball, F.; Beck, L.; Brooke, J. J.; Burns, D.; Clement, E.; Cussans, D.; Davignon, O.; Flacher, H.; Goldstein, J.; Grimes, M.; Heath, G. P.; Heath, H. F.; Jacob, J.; Kreczko, L.; Lucas, C.; Newbold, D. M.; Paramesvaran, S.; Poll, A.; Sakuma, T.; Seif El Nasr-storey, S.; Smith, D.; Smith, V. J.; Bell, K. W.; Belyaev, A.; Brew, C.; Brown, R. M.; Calligaris, L.; Cieri, D.; Cockerill, D. J. A.; Coughlan, J. A.; Harder, K.; Harper, S.; Olaiya, E.; Petyt, D.; Shepherd-Themistocleous, C. H.; Thea, A.; Tomalin, I. R.; Williams, T.; Auzinger, G.; Bainbridge, R.; Breeze, S.; Buchmuller, O.; Bundock, A.; Casasso, S.; Citron, M.; Colling, D.; Corpe, L.; Dauncey, P.; Davies, G.; De Wit, A.; Della Negra, M.; Di Maria, R.; Elwood, A.; Haddad, Y.; Hall, G.; Iles, G.; James, T.; Lane, R.; Laner, C.; Lyons, L.; Magnan, A.-M.; Malik, S.; Mastrolorenzo, L.; Matsushita, T.; Nash, J.; Nikitenko, A.; Palladino, V.; Pesaresi, M.; Raymond, D. M.; Richards, A.; Rose, A.; Scott, E.; Seez, C.; Shtipliyski, A.; Summers, S.; Tapper, A.; Uchida, K.; Vazquez Acosta, M.; Virdee, T.; Wardle, N.; Winterbottom, D.; Wright, J.; Zenz, S. C.; Cole, J. E.; Hobson, P. R.; Khan, A.; Kyberd, P.; Reid, I. D.; Symonds, P.; Teodorescu, L.; Turner, M.; Borzou, A.; Call, K.; Dittmann, J.; Hatakeyama, K.; Liu, H.; Pastika, N.; Smith, C.; Bartek, R.; Dominguez, A.; Buccilli, A.; Cooper, S. I.; Henderson, C.; Rumerio, P.; West, C.; Arcaro, D.; Avetisyan, A.; Bose, T.; Gastler, D.; Rankin, D.; Richardson, C.; Rohlf, J.; Sulak, L.; Zou, D.; Benelli, G.; Cutts, D.; Garabedian, A.; Hakala, J.; Heintz, U.; Hogan, J. M.; Kwok, K. H. M.; Laird, E.; Landsberg, G.; Mao, Z.; Narain, M.; Pazzini, J.; Piperov, S.; Sagir, S.; Syarif, R.; Yu, D.; Band, R.; Brainerd, C.; Burns, D.; Calderon De La Barca Sanchez, M.; Chertok, M.; Conway, J.; Conway, R.; Cox, P. T.; Erbacher, R.; Flores, C.; Funk, G.; Gardner, M.; Ko, W.; Lander, R.; Mclean, C.; Mulhearn, M.; Pellett, D.; Pilot, J.; Shalhout, S.; Shi, M.; Smith, J.; Squires, M.; Stolp, D.; Tos, K.; Tripathi, M.; Wang, Z.; Bachtis, M.; Bravo, C.; Cousins, R.; Dasgupta, A.; Florent, A.; Hauser, J.; Ignatenko, M.; Mccoll, N.; Saltzberg, D.; Schnaible, C.; Valuev, V.; Bouvier, E.; Burt, K.; Clare, R.; Ellison, J.; Gary, J. W.; Ghiasi Shirazi, S. M. A.; Hanson, G.; Heilman, J.; Jandir, P.; Kennedy, E.; Lacroix, F.; Long, O. R.; Olmedo Negrete, M.; Paneva, M. I.; Shrinivas, A.; Si, W.; Wang, L.; Wei, H.; Wimpenny, S.; Yates, B. R.; Branson, J. G.; Cittolin, S.; Derdzinski, M.; Gerosa, R.; Hashemi, B.; Holzner, A.; Klein, D.; Kole, G.; Krutelyov, V.; Letts, J.; Macneill, I.; Masciovecchio, M.; Olivito, D.; Padhi, S.; Pieri, M.; Sani, M.; Sharma, V.; Simon, S.; Tadel, M.; Vartak, A.; Wasserbaech, S.; Wood, J.; Würthwein, F.; Yagil, A.; Zevi Della Porta, G.; Amin, N.; Bhandari, R.; Bradmiller-Feld, J.; Campagnari, C.; Dishaw, A.; Dutta, V.; Franco Sevilla, M.; George, C.; Golf, F.; Gouskos, L.; Gran, J.; Heller, R.; Incandela, J.; Mullin, S. D.; Ovcharova, A.; Qu, H.; Richman, J.; Stuart, D.; Suarez, I.; Yoo, J.; Anderson, D.; Bendavid, J.; Bornheim, A.; Lawhorn, J. M.; Newman, H. B.; Nguyen, T.; Pena, C.; Spiropulu, M.; Vlimant, J. R.; Xie, S.; Zhang, Z.; Zhu, R. Y.; Andrews, M. B.; Ferguson, T.; Mudholkar, T.; Paulini, M.; Russ, J.; Sun, M.; Vogel, H.; Vorobiev, I.; Weinberg, M.; Cumalat, J. P.; Ford, W. T.; Jensen, F.; Johnson, A.; Krohn, M.; Leontsinis, S.; Mulholland, T.; Stenson, K.; Wagner, S. R.; Alexander, J.; Chaves, J.; Chu, J.; Dittmer, S.; Mcdermott, K.; Mirman, N.; Patterson, J. R.; Rinkevicius, A.; Ryd, A.; Skinnari, L.; Soffi, L.; Tan, S. M.; Tao, Z.; Thom, J.; Tucker, J.; Wittich, P.; Zientek, M.; Abdullin, S.; Albrow, M.; Apollinari, G.; Apresyan, A.; Apyan, A.; Banerjee, S.; Bauerdick, L. A. T.; Beretvas, A.; Berryhill, J.; Bhat, P. C.; Bolla, G.; Burkett, K.; Butler, J. N.; Canepa, A.; Cerati, G. B.; Cheung, H. W. K.; Chlebana, F.; Cremonesi, M.; Duarte, J.; Elvira, V. D.; Freeman, J.; Gecse, Z.; Gottschalk, E.; Gray, L.; Green, D.; Grünendahl, S.; Gutsche, O.; Harris, R. M.; Hasegawa, S.; Hirschauer, J.; Hu, Z.; Jayatilaka, B.; Jindariani, S.; Johnson, M.; Joshi, U.; Klima, B.; Kreis, B.; Lammel, S.; Lincoln, D.; Lipton, R.; Liu, M.; Liu, T.; Lopes De Sá, R.; Lykken, J.; Maeshima, K.; Magini, N.; Marraffino, J. M.; Maruyama, S.; Mason, D.; McBride, P.; Merkel, P.; Mrenna, S.; Nahn, S.; O'Dell, V.; Pedro, K.; Prokofyev, O.; Rakness, G.; Ristori, L.; Schneider, B.; Sexton-Kennedy, E.; Soha, A.; Spalding, W. J.; Spiegel, L.; Stoynev, S.; Strait, J.; Strobbe, N.; Taylor, L.; Tkaczyk, S.; Tran, N. V.; Uplegger, L.; Vaandering, E. W.; Vernieri, C.; Verzocchi, M.; Vidal, R.; Wang, M.; Weber, H. A.; Whitbeck, A.; Acosta, D.; Avery, P.; Bortignon, P.; Bourilkov, D.; Brinkerhoff, A.; Carnes, A.; Carver, M.; Curry, D.; Field, R. D.; Furic, I. K.; Konigsberg, J.; Korytov, A.; Kotov, K.; Ma, P.; Matchev, K.; Mei, H.; Mitselmakher, G.; Rank, D.; Sperka, D.; Terentyev, N.; Thomas, L.; Wang, J.; Wang, S.; Yelton, J.; Joshi, Y. R.; Linn, S.; Markowitz, P.; Rodriguez, J. L.; Ackert, A.; Adams, T.; Askew, A.; Hagopian, S.; Hagopian, V.; Johnson, K. F.; Kolberg, T.; Martinez, G.; Perry, T.; Prosper, H.; Saha, A.; Santra, A.; Sharma, V.; Yohay, R.; Baarmand, M. M.; Bhopatkar, V.; Colafranceschi, S.; Hohlmann, M.; Noonan, D.; Roy, T.; Yumiceva, F.; Adams, M. R.; Apanasevich, L.; Berry, D.; Betts, R. R.; Cavanaugh, R.; Chen, X.; Evdokimov, O.; Gerber, C. E.; Hangal, D. A.; Hofman, D. J.; Jung, K.; Kamin, J.; Sandoval Gonzalez, I. D.; Tonjes, M. B.; Trauger, H.; Varelas, N.; Wang, H.; Wu, Z.; Zhang, J.; Bilki, B.; Clarida, W.; Dilsiz, K.; Durgut, S.; Gandrajula, R. P.; Haytmyradov, M.; Khristenko, V.; Merlo, J.-P.; Mermerkaya, H.; Mestvirishvili, A.; Moeller, A.; Nachtman, J.; Ogul, H.; Onel, Y.; Ozok, F.; Penzo, A.; Snyder, C.; Tiras, E.; Wetzel, J.; Yi, K.; Blumenfeld, B.; Cocoros, A.; Eminizer, N.; Fehling, D.; Feng, L.; Gritsan, A. V.; Maksimovic, P.; Roskes, J.; Sarica, U.; Swartz, M.; Xiao, M.; You, C.; Al-bataineh, A.; Baringer, P.; Bean, A.; Boren, S.; Bowen, J.; Castle, J.; Khalil, S.; Kropivnitskaya, A.; Majumder, D.; Mcbrayer, W.; Murray, M.; Royon, C.; Sanders, S.; Schmitz, E.; Stringer, R.; Tapia Takaki, J. D.; Wang, Q.; Ivanov, A.; Kaadze, K.; Maravin, Y.; Mohammadi, A.; Saini, L. K.; Skhirtladze, N.; Toda, S.; Rebassoo, F.; Wright, D.; Anelli, C.; Baden, A.; Baron, O.; Belloni, A.; Calvert, B.; Eno, S. C.; Ferraioli, C.; Hadley, N. J.; Jabeen, S.; Jeng, G. Y.; Kellogg, R. G.; Kunkle, J.; Mignerey, A. C.; Ricci-Tam, F.; Shin, Y. H.; Skuja, A.; Tonwar, S. C.; Abercrombie, D.; Allen, B.; Azzolini, V.; Barbieri, R.; Baty, A.; Bi, R.; Brandt, S.; Busza, W.; Cali, I. A.; D'Alfonso, M.; Demiragli, Z.; Gomez Ceballos, G.; Goncharov, M.; Hsu, D.; Iiyama, Y.; Innocenti, G. M.; Klute, M.; Kovalskyi, D.; Lai, Y. S.; Lee, Y.-J.; Levin, A.; Luckey, P. D.; Maier, B.; Marini, A. C.; Mcginn, C.; Mironov, C.; Narayanan, S.; Niu, X.; Paus, C.; Roland, C.; Roland, G.; Salfeld-Nebgen, J.; Stephans, G. S. F.; Tatar, K.; Velicanu, D.; Wang, J.; Wang, T. W.; Wyslouch, B.; Benvenuti, A. C.; Chatterjee, R. M.; Evans, A.; Hansen, P.; Kalafut, S.; Kubota, Y.; Lesko, Z.; Mans, J.; Nourbakhsh, S.; Ruckstuhl, N.; Rusack, R.; Turkewitz, J.; Acosta, J. G.; Oliveros, S.; Avdeeva, E.; Bloom, K.; Claes, D. R.; Fangmeier, C.; Gonzalez Suarez, R.; Kamalieddin, R.; Kravchenko, I.; Monroy, J.; Siado, J. E.; Snow, G. R.; Stieger, B.; Alyari, M.; Dolen, J.; Godshalk, A.; Harrington, C.; Iashvili, I.; Nguyen, D.; Parker, A.; Rappoccio, S.; Roozbahani, B.; Alverson, G.; Barberis, E.; Hortiangtham, A.; Massironi, A.; Morse, D. M.; Nash, D.; Orimoto, T.; Teixeira De Lima, R.; Trocino, D.; Wood, D.; Bhattacharya, S.; Charaf, O.; Hahn, K. A.; Mucia, N.; Odell, N.; Pollack, B.; Schmitt, M. H.; Sung, K.; Trovato, M.; Velasco, M.; Dev, N.; Hildreth, M.; Hurtado Anampa, K.; Jessop, C.; Karmgard, D. J.; Kellams, N.; Lannon, K.; Loukas, N.; Marinelli, N.; Meng, F.; Mueller, C.; Musienko, Y.; Planer, M.; Reinsvold, A.; Ruchti, R.; Smith, G.; Taroni, S.; Wayne, M.; Wolf, M.; Woodard, A.; Alimena, J.; Antonelli, L.; Bylsma, B.; Durkin, L. S.; Flowers, S.; Francis, B.; Hart, A.; Hill, C.; Ji, W.; Liu, B.; Luo, W.; Puigh, D.; Winer, B. L.; Wulsin, H. W.; Cooperstein, S.; Driga, O.; Elmer, P.; Hardenbrook, J.; Hebda, P.; Higginbotham, S.; Lange, D.; Luo, J.; Marlow, D.; Mei, K.; Ojalvo, I.; Olsen, J.; Palmer, C.; Piroué, P.; Stickland, D.; Tully, C.; Malik, S.; Norberg, S.; Barker, A.; Barnes, V. E.; Das, S.; Folgueras, S.; Gutay, L.; Jha, M. K.; Jones, M.; Jung, A. W.; Khatiwada, A.; Miller, D. H.; Neumeister, N.; Peng, C. C.; Schulte, J. F.; Sun, J.; Wang, F.; Xie, W.; Cheng, T.; Parashar, N.; Stupak, J.; Adair, A.; Akgun, B.; Chen, Z.; Ecklund, K. M.; Geurts, F. J. M.; Guilbaud, M.; Li, W.; Michlin, B.; Northup, M.; Padley, B. P.; Roberts, J.; Rorie, J.; Tu, Z.; Zabel, J.; Bodek, A.; de Barbaro, P.; Demina, R.; Duh, Y. t.; Ferbel, T.; Galanti, M.; Garcia-Bellido, A.; Han, J.; Hindrichs, O.; Khukhunaishvili, A.; Lo, K. H.; Tan, P.; Verzetti, M.; Ciesielski, R.; Goulianos, K.; Mesropian, C.; Agapitos, A.; Chou, J. P.; Gershtein, Y.; Gómez Espinosa, T. A.; Halkiadakis, E.; Heindl, M.; Hughes, E.; Kaplan, S.; Kunnawalkam Elayavalli, R.; Kyriacou, S.; Lath, A.; Montalvo, R.; Nash, K.; Osherson, M.; Saka, H.; Salur, S.; Schnetzer, S.; Sheffield, D.; Somalwar, S.; Stone, R.; Thomas, S.; Thomassen, P.; Walker, M.; Delannoy, A. G.; Foerster, M.; Heideman, J.; Riley, G.; Rose, K.; Spanier, S.; Thapa, K.; Bouhali, O.; Castaneda Hernandez, A.; Celik, A.; Dalchenko, M.; De Mattia, M.; Delgado, A.; Dildick, S.; Eusebi, R.; Gilmore, J.; Huang, T.; Kamon, T.; Mueller, R.; Pakhotin, Y.; Patel, R.; Perloff, A.; Perniè, L.; Rathjens, D.; Safonov, A.; Tatarinov, A.; Ulmer, K. A.; Akchurin, N.; Damgov, J.; De Guio, F.; Dudero, P. R.; Faulkner, J.; Gurpinar, E.; Kunori, S.; Lamichhane, K.; Lee, S. W.; Libeiro, T.; Peltola, T.; Undleeb, S.; Volobouev, I.; Wang, Z.; Greene, S.; Gurrola, A.; Janjam, R.; Johns, W.; Maguire, C.; Melo, A.; Ni, H.; Sheldon, P.; Tuo, S.; Velkovska, J.; Xu, Q.; Arenton, M. W.; Barria, P.; Cox, B.; Hirosky, R.; Ledovskoy, A.; Li, H.; Neu, C.; Sinthuprasith, T.; Wang, Y.; Wolfe, E.; Xia, F.; Harr, R.; Karchin, P. E.; Sturdy, J.; Zaleski, S.; Brodski, M.; Buchanan, J.; Caillol, C.; Dasu, S.; Dodd, L.; Duric, S.; Gomber, B.; Grothe, M.; Herndon, M.; Hervé, A.; Hussain, U.; Klabbers, P.; Lanaro, A.; Levine, A.; Long, K.; Loveless, R.; Pierro, G. A.; Polese, G.; Ruggles, T.; Savin, A.; Smith, N.; Smith, W. H.; Taylor, D.; Woods, N.

2018-03-01

Search results are presented for physics beyond the standard model in final states with two opposite-charge, same-flavor leptons, jets, and missing transverse momentum. The data sample corresponds to an integrated luminosity of 35.9 fb-1 of proton-proton collisions at √{s}=13 TeV collected with the CMS detector at the LHC in 2016. The analysis uses the invariant mass of the lepton pair, searching for a kinematic edge or a resonant-like excess compatible with the Z boson mass. The search for a kinematic edge targets production of particles sensitive to the strong force, while the resonance search targets both strongly and electroweakly produced new physics. The observed yields are consistent with the expectations from the standard model, and the results are interpreted in the context of simplified models of supersymmetry. In a gauge mediated supersymmetry breaking (GMSB) model of gluino pair production with decay chains including Z bosons, gluino masses up to 1500-1770 GeV are excluded at the 95% confidence level depending on the lightest neutralino mass. In a model of electroweak chargino-neutralino production, chargino masses as high as 610 GeV are excluded when the lightest neutralino is massless. In GMSB models of electroweak neutralino-neutralino production, neutralino masses up to 500-650 GeV are excluded depending on the decay mode assumed. Finally, in a model with bottom squark pair production and decay chains resulting in a kinematic edge in the dilepton invariant mass distribution, bottom squark masses up to 980-1200 GeV are excluded depending on the mass of the next-to-lightest neutralino. [Figure not available: see fulltext.

Search for new phenomena in final states with two opposite-charge, same-flavor leptons, jets, and missing transverse momentum in pp collisions at $$ \\sqrt{s}=13 $$ TeV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sirunyan, Albert M; et al.

2018-03-13

Search results are presented for physics beyond the standard model in final states with two opposite-charge, same-flavor leptons, jets, and missing transverse momentum. The data sample corresponds to an integrated luminosity of 35.9 fbmore » $$^{-1}$$ of proton-proton collisions at $$\\sqrt{s} = $$ 13 TeV collected with the CMS detector at the LHC in 2016. The analysis uses the invariant mass of the lepton pair, searching for a kinematic edge or a resonant-like excess compatible with the Z boson mass. The search for a kinematic edge targets production of particles sensitive to the strong force, while the resonance search targets both strongly and electroweakly produced new physics. The observed yields are consistent with the expectations from the standard model, and the results are interpreted in the context of simplified models of supersymmetry. In a gauge mediated supersymmetry breaking (GMSB) model of gluino pair production with decay chains including Z bosons, gluino masses up to 1500-1770 GeV are excluded at the 95% confidence level depending on the lightest neutralino mass. In a model of electroweak chargino-neutralino production, chargino masses as high as 610 GeV are excluded when the lightest neutralino is massless. In GMSB models of electroweak neutralino-neutralino production, neutralino masses up to 500-650 GeV are excluded depending on the decay mode assumed. Finally, in a model with bottom squark pair production and decay chains resulting in a kinematic edge in the dilepton invariant mass distribution, bottom squark masses up to 980-1200 GeV are excluded depending on the mass of the next-to-lightest neutralino.« less

Resonances in Positronium Hydride

NASA Technical Reports Server (NTRS)

DiRienzi, Joseph; Drachman, Richard J.; Fisher, Richard R. (Technical Monitor)

2001-01-01

We re-examine the problem of calculating the positions and widths of the lowest-lying resonances in the Ps + H scattering system which consists of two electrons, one positron and one proton. The first of these resonances, for L=0, was found by the methods of complex rotation and stabilization, and later described as a Feshbach resonance lying close to a bound state in the closed-channel e (+) + H (-) system. Recently, results for the L=1 and 2 scattering states were published, and it was found, surprisingly, that there is a larae shift in the positions of these resonances. In this work we repeat the analysis for L=1 and find an unexpected explanation for the shift.

75 FR 1770 - Proposed Consent Decree, Clean Air Act Citizen Suit

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-13

...:30 a.m. and 4:30 p.m. Monday through Friday, excluding legal holidays. Comments on a disk or CD-ROM... parties or intervenors to the litigation in question. EPA or the Department of Justice may withdraw or... the Act. Unless EPA or the Department of Justice determines that consent to this consent decree should...

Restricted Opportunities under Employment Reform: The Experiences of Select Universities in the Chinese Mainland

ERIC Educational Resources Information Center

Lai, Manhong; Du, Ping; Lo, Leslie N. K.

2016-01-01

This study investigates changes to academic work life under recent employment reform in the Chinese Mainland. It employs a mixed-methods research approach, first conducting a survey of 1,770 teachers at nine universities in Mainland China. These nine universities consist of first-tier, second-tier, and ordinary universities. Next, through a…

A Nation of Learners.

ERIC Educational Resources Information Center

Goodman, Leroy V., Ed.; And Others

Thirty-nine articles provide a composite picture of American education as it has developed during the past 200 years. Most of the articles are written by educators. Vignettes of daily routines in a one-room schoolhouse in 1775 and a description of how a log college was built in Pennsylvania in the 1770s indicate the process and philosophy of…

Thomas Berdmore, dentist of His Majesty, George III, and dental calculus.

PubMed

Andreana, S; Andreana, G; Gonzalez, Y M; Ciancio, S

1996-11-01

Thomas Berdmore's book, Disorders of Deformities of the Teeth and Gums, presents examples of early concepts of preventive dentistry and treatment of periodontal diseases. Various aspects of dental calculus formation and composition are analyzed. Also the effects of periodontal disease as seen by Berdmore are discussed, and ways of treatment in 1770 summarized.

75 FR 1770 - An Approach to Using Toxicogenomic Data in U.S. EPA Human Health Risk Assessments: A Dibutyl...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-13

... qualitative aspects of the risk assessment because of the type of genomic data available for DBP. It is... Assessment (NCEA) within EPA's Office of Research and Development (ORD). Toxicogenomics is the application of... exploratory methods for analyzing genomic data for application to risk assessment and some preliminary results...

Publications - GMC 290 | Alaska Division of Geological & Geophysical

Science.gov Websites

DGGS GMC 290 Publication Details Title: Organic carbon and rock-eval pyrolysis data of cuttings from Reference Unknown, 1999, Organic carbon and rock-eval pyrolysis data of cuttings from the Husky Oil NPR Products Report Report Information gmc290.pdf (177.0 K) Keywords Pyrolysis; Rock-Eval Pyrolysis Top of Page

The Relationship between the Perception of Distributed Leadership in Secondary Schools and Teachers' and Teacher Leaders' Job Satisfaction and Organizational Commitment

ERIC Educational Resources Information Center

Hulpia, Hester; Devos, Geert; Rosseel, Yves

2009-01-01

This study investigates the relation between distributed leadership, the cohesion of the leadership team, participative decision-making, context variables, and the organizational commitment and job satisfaction of teachers and teacher leaders. A questionnaire was administered to teachers and teacher leaders (n = 1770) from 46 large secondary…

[Quality of life during and after therapy].

PubMed

Taieb, Julien

2015-01-01

With a three-fold increase in life expectancy between 1770 and 1970 in western countries, but no significant improvement since then, quality of life (QoL) has progressively become more and more important for healthcare evaluation. Using the classical evidence-based methods, QoL remains, however, quite difficult to assess and to analyse. Colorectal cancer is a frequent and severe disease. Major therapeutic advances have, however, been made during the past two decades. Currently 75% of patients with a non metastatic disease may expect, after surgical removal of their primary tumor; a long lasting remission. This is also the case in 40% of patients with metastatic disease suitable for surgery. Finally, in non-surgical, advanced disease stage cases, median overall survival moved from 6 to 30 months. As treatment duration and percentage of remissions increased, QoL has been more and more studied in these patients. Follow-up of patients receiving adjuvant chemotherapy following complete surgical removal showed treatment-induced side effects impairing long term QoL. This has led to stopping rules. International consortiums have been developed in order to perform extremely large clinical trials so as to decrease the duration of adjuvant treatments, and thus limit the occurrence of the long lasting side effects impairing QoL. In patients with a more advanced disease, de-escalation of treatment intensity has been successfully evaluated, leading to the use of maintenance therapy, in order to preserve both patients' survival and QoL. These approaches have simplified treatment schedules, decreased the incidence of clinically relevant side effects and significantly improved patients QoL. They are currently part of our practice routine. If QoL seems today important in clinical trials and medico-economic assessment of new anti-cancer agents, it may be tomorrow integrated in daily practice through dedicated software in day hospital units in order to better choose each patients' tailored treatment.

''Reading'' the photoelectron {beta}-parameter spectrum in a resonance region

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dolmatov, V. K.; Guler, E.; Manson, S. T.

2007-09-15

The behavior of the dipole photoelectron angular distribution parameter {beta}{sub nl}({omega}) in the vicinity of autoionizing resonances is discussed. It is shown that from this behavior, surprisingly, many photoionization parameters that cannot be measured experimentally can be extracted. These are the energy positions and ordering of autoionizing resonance minima in the partial photoionization cross sections {sigma}{sub l+1} and {sigma}{sub l-1}, the energies at which these two cross sections intersect, and signs and magnitudes of the cos({delta}{sub l+1}-{delta}{sub l-1}) ({delta}{sub l{+-}}{sub 1} being the phase shifts of the dipole photoionization amplitudes D{sub l{+-}}{sub 1}, respectively) through the autoionizing resonance energy region.more » Based on this, a deeper interpretation of such effects as the width-narrowing, width-fluctuating, and q-reversal in the {beta}{sub nl} parameter spectrum in the autoionizing resonance energy region is given. As an example, calculated data for partial photoionization cross sections {sigma}{sub 3d{r_reversible}}{sub f} and {sigma}{sub 3d{r_reversible}}{sub p}, and {beta}{sub 3d} parameters for 3d photoelectrons from Cr{sup +} are presented.« less

RESONANT AMPLIFICATION OF TURBULENCE BY THE BLAST WAVES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zankovich, A. M.; Kovalenko, I. G., E-mail: ilya.g.kovalenko@gmail.com

2015-02-10

We discuss the idea of whether spherical blast waves can amplify by a nonlocal resonant hydrodynamic mechanism inhomogeneities formed by turbulence or phase segregation in the interstellar medium. We consider the problem of a blast-wave-turbulence interaction in the Linear Interaction Approximation. Mathematically, this is an eigenvalue problem for finding the structure and amplitude of eigenfunctions describing the response of the shock-wave flow to forced oscillations by external perturbations in the ambient interstellar medium. Linear analysis shows that the blast wave can amplify density and vorticity perturbations for a wide range of length scales with amplification coefficients of up to 20,more » with increasing amplification the larger the length. There also exist resonant harmonics for which the gain becomes formally infinite in the linear approximation. Their orbital wavenumbers are within the range of macro- (l ∼ 1), meso- (l ∼ 20), and microscopic (l > 200) scales. Since the resonance width is narrow (typically, Δl < 1), resonance should select and amplify discrete isolated harmonics. We speculate on a possible explanation of an observed regular filamentary structure of regularly shaped round supernova remnants such as SNR 1572, 1006, or 0509-67.5. Resonant mesoscales found (l ≈ 18) are surprisingly close to the observed scales (l ≈ 15) of ripples in the shell's surface of SNR 0509-67.5.« less

32 CFR Appendix C to Part 231 - Sample Certificate of Compliance for Credit Unions Certificate of Compliance

Code of Federal Regulations, 2010 CFR

2010-07-01

... Unions Certificate of Compliance C Appendix C to Part 231 National Defense Department of Defense... UNIONS AND OTHER FINANCIAL INSTITUTIONS ON DOD INSTALLATIONS Pt. 231, App. C Appendix C to Part 231... union complies with the requirements of section 170 of the Federal Credit Union Act (12 U.S.C 1770), for...

Raman spectroscopic analysis of archaeological specimens from the wreck of HMS Swift, 1770

NASA Astrophysics Data System (ADS)

Edwards, Howell G. M.; Elkin, Dolores; Maier, Marta S.

2016-12-01

Specimens from underwater archaeological excavations have rarely been analysed by Raman spectroscopy probably due to the problems associated with the presence of water and the use of alternative techniques. The discovery of the remains of the Royal Navy warship HMS Swift off the coast of Patagonia, South America, which was wrecked in 1770 while undertaking a survey from its base in the Falkland/Malvinas Islands, has afforded the opportunity for a first-pass Raman spectroscopic study of the contents of several glass jars from a wooden chest, some of which had suffered deterioration of their contents owing to leakage through their stoppers. From the Raman spectroscopic data, it was possible to identify organic compounds such as anthraquinone and copal resin, which were empirically used as materia medica in the eighteenth century to treat shipboard diseases; it seems very likely, therefore, that the wooden chest belonged to the barber-surgeon on the ship. Spectra were obtained from the wet and desiccated samples, but several samples from containers that had leaked were found to contain only minerals, such as aragonite and sediment. This article is part of the themed issue "Raman spectroscopy in art and archaeology".

Raman spectroscopic analysis of archaeological specimens from the wreck of HMS Swift, 1770.

PubMed

Edwards, Howell G M; Elkin, Dolores; Maier, Marta S

2016-12-13

Specimens from underwater archaeological excavations have rarely been analysed by Raman spectroscopy probably due to the problems associated with the presence of water and the use of alternative techniques. The discovery of the remains of the Royal Navy warship HMS Swift off the coast of Patagonia, South America, which was wrecked in 1770 while undertaking a survey from its base in the Falkland/Malvinas Islands, has afforded the opportunity for a first-pass Raman spectroscopic study of the contents of several glass jars from a wooden chest, some of which had suffered deterioration of their contents owing to leakage through their stoppers. From the Raman spectroscopic data, it was possible to identify organic compounds such as anthraquinone and copal resin, which were empirically used as materia medica in the eighteenth century to treat shipboard diseases; it seems very likely, therefore, that the wooden chest belonged to the barber-surgeon on the ship. Spectra were obtained from the wet and desiccated samples, but several samples from containers that had leaked were found to contain only minerals, such as aragonite and sediment.This article is part of the themed issue 'Raman spectroscopy in art and archaeology'. © 2016 The Author(s).

Raman spectroscopic analysis of archaeological specimens from the wreck of HMS Swift, 1770

PubMed Central

Elkin, Dolores

2016-01-01

Specimens from underwater archaeological excavations have rarely been analysed by Raman spectroscopy probably due to the problems associated with the presence of water and the use of alternative techniques. The discovery of the remains of the Royal Navy warship HMS Swift off the coast of Patagonia, South America, which was wrecked in 1770 while undertaking a survey from its base in the Falkland/Malvinas Islands, has afforded the opportunity for a first-pass Raman spectroscopic study of the contents of several glass jars from a wooden chest, some of which had suffered deterioration of their contents owing to leakage through their stoppers. From the Raman spectroscopic data, it was possible to identify organic compounds such as anthraquinone and copal resin, which were empirically used as materia medica in the eighteenth century to treat shipboard diseases; it seems very likely, therefore, that the wooden chest belonged to the barber-surgeon on the ship. Spectra were obtained from the wet and desiccated samples, but several samples from containers that had leaked were found to contain only minerals, such as aragonite and sediment. This article is part of the themed issue ‘Raman spectroscopy in art and archaeology’. PMID:27799436

A history of calcium orthophosphates (CaPO4) and their biomedical applications.

PubMed

Dorozhkin, S V

2017-09-01

The historical development of a scientific knowledge on calcium orthophosphates (CaPO 4 ) from 1770-s till 1950 is described. Many forgotten and poorly known historical facts and approaches have been extracted from old publications and then they have been analyzed, systematized and reconsidered from the modern point of view. The chosen time scale starts with the earliest available studies of 1770-s (to the best of my findings, CaPO 4 had been unknown before), passes through the entire 19th century and finishes in 1950, because since then the amount of publications on CaPO 4 rapidly increases and the subject becomes too broad. Furthermore, since publications of the second half of the 20th century are easily accessible, the substantial amount of them has been already reviewed by other researchers. The reported historical findings clearly demonstrate that the substantial amount of the scientific facts and experimental approaches has been known for very many decades and, in fact, the considerable quantity of relatively recent investigations on CaPO 4 is just either a further development of the earlier studies or a rediscovery of the already forgotten knowledge. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

[Reception of research in the natural sciences in middle Germany at the Padua University betwee 1770 and 1820].

PubMed

Breidbach, Olaf; Frigo, Gian Franco

2004-01-01

The German literature on natural sciences that was present in the public libraries in Padua between 1770 and 1820 is described. The citations of German authors in the publications of Paduan naturalists of that time and of the textbooks used in Padua University are outlined. German journals on natural sciences available in Venice and Padua and Italian translations of German monographs of that time are also documented. With the foundation of the Italian Empire by Napoleon, the organization of lectures and research in the University of Padua changed drastically. In consequence, the reception of chemistry and physics was exclusively directed to France. In the descriptive natural sciences the earlier German traditions prevailed. Therein, however, Paduan sciences adopted the earlier descriptive traditions that already existed at the end of the 18th century and did not respond to the new developments in German functional morphology and physiology. Jenensian naturalists, botanists and physicists who received attention in Padua around 1800 are described as part of the empiric tradition of Central Germany and not as followers of the speculative "Naturphilosophie". There is no explicit reference to romantic sciences.

Vectors expressing chimeric Japanese encephalitis dengue 2 viruses.

PubMed

Wei, Y; Wang, S; Wang, X

2014-01-01

Vectors based on self-replicating RNAs (replicons) of flaviviruses are becoming powerful tool for expression of heterologous genes in mammalian cells and development of novel antiviral and anticancer vaccines. We constructed two vectors expressing chimeric viruses consisting of attenuated SA14-14-2 strain of Japanese encephalitis virus (JEV) in which the PrM/M-E genes were replaced fully or partially with those of dengue 2 virus (DENV-2). These vectors, named pJED2 and pJED2-1770 were transfected to BHK-21 cells and produced chimeric viruses JED2V and JED2-1770V, respectively. The chimeric viruses could be passaged in C6/36 but not BHK-21 cells. The chimeric viruses produced in C6/36 cells CPE 4-5 days after infection and RT-PCR, sequencing, immunofluorescence assay (IFA) and Western blot analysis confirmed the chimeric nature of produced viruses. The immunogenicity of chimeric viruses in mice was proved by detecting DENV-2 E protein-specific serum IgG antibodies with neutralization titer of 10. Successful preparation of infectious clones of chimeric JEV-DENV-2 viruses showed that JEV-based expression vectors are fully functional.

Equivalent circuit for the characterization of the resonance mode in piezoelectric systems

NASA Astrophysics Data System (ADS)

Fernández-Afonso, Y.; García-Zaldívar, O.; Calderón-Piñar, F.

2015-12-01

The impedance properties in polarized piezoelectric can be described by electric equivalent circuits. The classic circuit used in the literature to describe real systems is formed by one resistor (R), one inductance (L) and one capacitance C connected in series and one capacity (C0) connected in parallel with the formers. Nevertheless, the equation that describe the resonance and anti-resonance frequencies depends on a complex manner of R, L, C and C0. In this work is proposed a simpler model formed by one inductance (L) and one capacity (C) in series; one capacity (C0) in parallel; one resistor (RP) in parallel and one resistor (RS) in series with other components. Unlike the traditional circuit, the equivalent circuit elements in the proposed model can be simply determined by knowing the experimental values of the resonance frequency fr, anti-resonance frequency fa, impedance module at resonance frequency |Zr|, impedance module at anti-resonance frequency |Za| and low frequency capacitance C0, without fitting the impedance experimental data to the obtained equation.

The Trickling Filter/Solids Contact Process: Application to Army Wastewater Plants

DTIC Science & Technology

1988-08-01

technology (activated sludge and rotating biological contactors [RBC]). 3 7 For the study, the plant was to be sized at 10 mgd. Electricity purchased from...Project Costs* Estimated Cost** ($K) Trickling Rotating Filter/Solids Activated Biological Item Contact Sludge Contactor Preliminary treatment 1100 1100...basins 4500 - Rotating biological contactor reactors - 4520 Flocculator clarifiers 2000 - - Conventional secondary clarifiers 1770 1500 Dual-media

INTERIOR VIEW, CENTER CHAMBER OVER THE SALOON FROM THE NORTH. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

INTERIOR VIEW, CENTER CHAMBER OVER THE SALOON FROM THE NORTH. THE DOORS ON THE RIGHT CONCEAL CLOSETS. THIS SECTION OF THE HOUSE WAS PART OF THE ORIGINAL CA. 1770 CONSTRUCTION. THE FLOOR-LEVEL WINDOW RESULTED FROM THE 1780S RECONCEPTION OF THE HOUSE WHICH INCLUDED RAISING THE FLOOR TO ACCOMMODATE THE SALOON’S CEILING - The Woodlands, 4000 Woodlands Avenue, Philadelphia, Philadelphia County, PA

DETAIL VIEW, STRUCTURAL TIMBER AND FLOOR JOISTS, SOUTH GARRET. THIS ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

DETAIL VIEW, STRUCTURAL TIMBER AND FLOOR JOISTS, SOUTH GARRET. THIS TIMBER IS ONE OF TWO EXTENDING OUT FROM THE HOUSE AND JOINED TO VERTICAL POSTS LOCATED WITHIN THE WOOD TUSCAN COLUMNS LOCATED AT THE PORTICO’S TWO OUTER CORNERS. THE TIMBERS AND THE VISIBLE FLOOR JOISTS WERE PART OF THE HOUSE’S INITIAL CA. 1770 CONSTRUCTION - The Woodlands, 4000 Woodlands Avenue, Philadelphia, Philadelphia County, PA

American Indians of the Local Region. Grade 3 Model Lesson for Unit 2, Standard 2. California History-Social Science Course Models.

ERIC Educational Resources Information Center

Mastin, Susan

The indigenous people of the Los Angeles, California, region were called Gabrielino Indians by the first Spanish explorers. They were possibly the richest, largest, and most powerful tribe in southern California. In 1770 there were about 5,000 Gabrielino (or Tongva) Indians in the area, but smallpox, introduced by the explorers, killed most of…

Reduction in blood pressure and serum lipids by lycosome formulation of dark chocolate and lycopene in prehypertension.

PubMed

Petyaev, Ivan M; Dovgalevsky, Pavel Y; Chalyk, Natalia E; Klochkov, Victor; Kyle, Nigel H

2014-11-01

Twenty-nine healthy volunteers aged 47-69 years old were randomly assigned to a 28-day oral intake of different dark chocolate (DC) formulations. The main group received daily 30 g of proprietary lycopene-containing (L-tug) lycosome formulation of DC with enhanced bioavailability of cocoa flavanols. Two control groups daily consumed either 30 g of regular DC alone or along with 7 mg of lycopene, which corresponds to the amount of lycopene ingested with L-tug formulation. It was found that L-tug was more efficient in reducing diastolic blood pressure (mean value of -6.22 mmHg, 95% CI: 5.00, 8.00) when compared with the regular DC group (-3.00 mmHg, P < 0.05) or the group which ingested the DC and lycopene as two separate formulations (mean reduction of -4 mmHg, 95% CI: 2.47, 6.00, P = 0.0262). Only marginal superiority for L-tug formulation in the reduction in systolic blood pressure was seen. However, the L-tug formulation was the only formulation of DC which affected serum lipids. There was a reduction in total cholesterol (from median 228.00 mg/dL [95% CI: 206.2, 242.5] to 187.00 mg/dL [95% CI: 166.2, 202.2, P < 0.05]) with corresponding decline of low-density lipoprotein (LDL) cholesterol (from a median of 166.00 mg/dL [95% CI: 130.8, 177.0] to 151.00 mg/dL [95% CI: 122.8, 167.4; P < 0.05]) at the end of the intervention period. Similar decline was seen in serum triglycerides (P < 0.05). Serum high-density lipoprotein (HDL) cholesterol, glucose levels, and C-reactive protein (CRP) values remained statistically unchanged in all study groups throughout the intervention period. A superior biological activity of the L-tug lycosome formulation of DC extending beyond its antihypertensive effect to lipid-lowering ability opens up new possibilities for the use of DC for health purposes helping to reduce daily caloric intake without compromising on the health benefits of DC consumption.

[The knowledge of animal respiration as a combustion phenomenon].

PubMed

de Micheli, Alfredo

2014-01-01

The different stages leading to knowledge of the phenomenon of animal breathing are going from some writings in Corpus Hippocraticum to Aristoteles' and Galen's works, who considered the heart as the source of the animal heat. Later, Miguel Servet suggested that the inspired air can achieve other functions besides cooling the blood. After that, different explications of the animal heat were raised. About 1770, due to progress of knowledge in the chemistry field, first Mayow and later Black began to consider the animal respiration as a combustion. The important treatise Méthode de nomenclature chimique, published by Guyton de Morveau et al. in 1787 and soon after the Traité élémentaire de chimie de Lavoisier (1789) provided a solid support to Lavoisier's thought. This way on arrived to consider analogous the respiration and combustion phenomena. Studies on the animal respiration phenomenon continued in xix century and in the following century it was possible to apply thermodynamic principles to biology: "generalized thermodynamics". Copyright © 2013 Instituto Nacional de Cardiología Ignacio Chávez. Published by Masson Doyma México S.A. All rights reserved.

Resonances in the optical response of a slab with time-periodic dielectric function {epsilon}(t)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zurita-Sanchez, Jorge R.; Halevi, P.

2010-05-15

We demonstrate that the optical response of a periodically modulated dynamic slab exhibits infinite resonances for frequencies {omega}=({Omega}/2)(2l+1), namely, odd multiples of one-half of the modulating frequency {Omega} of the dielectric function {epsilon}(t). These frequencies coincide partially with the usual condition of parametric amplification. However, the resonances occur only for certain normalized slab thicknesses L{sub R}. These resonances follow from detailed numerical studies based on our recent paper [Zurita-Sanchez, Halevi, and Cervantes-Gonzalez, Phys. Rev. A 79, 053821 (2009)]. As the thickness L nearly matches a resonance thickness L{sub R}, the amplitudes of counterpropagating modes in the slab obey a conditionmore » implying that both have the same modulus and their phases match a condition related to L{sub R} and the bulk wave vectors. When this condition is met, the electric field profile inside the slab is a superposition of standing waves with odd and even symmetries, and the reflection and transmission coefficients can reach great values and become infinite at exact resonance. Numerical simulations of the optical response are shown for a sinusoidal {epsilon}(t) with either moderate or strong modulation. As expected, as the modulation strength increases, higher-order harmonics {omega}-n{Omega} (n=0,{+-}1,{+-}2,...) become more noticeable, and short-wavelength bulk modes contribute significantly. However, we found that, regardless of the excitation frequency {omega}=({Omega}/2)(2l+1), the dominant spectral component of the generated fields is {Omega}/2. Also, as the excitation frequency increases, the parity of the standing waves is conserved.« less

A study of the piezoelectric resonance in metal organic NLO single crystals: Sodium D-isoascorbate monohydrate and Lithium L-ascorbate dihydrate

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saripalli, Ravi Kiran, E-mail: rksaripalli@physics.iisc.ernet.in; Sanath Kumar, R.; Elizabeth, Suja

2016-05-06

Large single crystals of Sodium D-isoacsorbate monohydrate and Lithium L-ascorbate dehydrate were grown using solution growth technique. Dielectric constant and dielectric loss were monitored as a function of frequency at different temperatures. These are typically characterized by strong resonance peaks. The piezoelectric coefficients d{sub 31}, elastic coefficient (S{sub 11}) and electromechanical coupling coefficient (k{sub 31}) were estimated by resonance-antiresonance method. The temperature dependence of the resonance-peaks frequencies was studied.

Soil fluoride spiking effects on olive trees (Olea europaea L. cv. Chemlali).

PubMed

Zouari, M; Ben Ahmed, C; Fourati, R; Delmail, D; Ben Rouina, B; Labrousse, P; Ben Abdallah, F

2014-10-01

A pot experiment under open air conditions was carried out to investigate the uptake, accumulation and toxicity effects of fluoride in olive trees (Olea europaea L.) grown in a soil spiked with inorganic sodium fluoride (NaF). Six different levels (0, 20, 40, 60, 80 and 100mM NaF) of soil spiking were applied through NaF to irrigation water. At the end of the experiment, total fluoride content in soil was 20 and 1770mgFkg(-1) soil in control and 100mM NaF treatments, respectively. The comparative distribution of fluoride partitioning among the different olive tree parts showed that the roots accumulated the most fluoride and olive fruits were minimally affected by soil NaF spiking as they had the lowest fluoride content. In fact, total fluoride concentration varied between 12 and 1070µgFg(-1) in roots, between 9 and 570µgFg(-1) in shoots, between 12 and 290µgFg(-1) in leaves, and between 10 and 29µgFg(-1) in fruits, respectively for control and 100mM NaF treatments. Indeed, the fluoride accumulation pattern showed the following distribution: roots>shoots>leaves>fruits. On the other hand, fluoride toxicity symptoms such as leaf necrosis and leaf drop appeared only in highly spiked soils (60, 80 and 100mM NaF). Copyright © 2014 Elsevier Inc. All rights reserved.

Automatic segmentation of vessels in in-vivo ultrasound scans

NASA Astrophysics Data System (ADS)

Tamimi-Sarnikowski, Philip; Brink-Kjær, Andreas; Moshavegh, Ramin; Arendt Jensen, Jørgen

2017-03-01

Ultrasound has become highly popular to monitor atherosclerosis, by scanning the carotid artery. The screening involves measuring the thickness of the vessel wall and diameter of the lumen. An automatic segmentation of the vessel lumen, can enable the determination of lumen diameter. This paper presents a fully automatic segmentation algorithm, for robustly segmenting the vessel lumen in longitudinal B-mode ultrasound images. The automatic segmentation is performed using a combination of B-mode and power Doppler images. The proposed algorithm includes a series of preprocessing steps, and performs a vessel segmentation by use of the marker-controlled watershed transform. The ultrasound images used in the study were acquired using the bk3000 ultrasound scanner (BK Ultrasound, Herlev, Denmark) with two transducers "8L2 Linear" and "10L2w Wide Linear" (BK Ultrasound, Herlev, Denmark). The algorithm was evaluated empirically and applied to a dataset of in-vivo 1770 images recorded from 8 healthy subjects. The segmentation results were compared to manual delineation performed by two experienced users. The results showed a sensitivity and specificity of 90.41+/-11.2 % and 97.93+/-5.7% (mean+/-standard deviation), respectively. The amount of overlap of segmentation and manual segmentation, was measured by the Dice similarity coefficient, which was 91.25+/-11.6%. The empirical results demonstrated the feasibility of segmenting the vessel lumen in ultrasound scans using a fully automatic algorithm.

Study of node and mass sensitivity of resonant mode based cantilevers with concentrated mass loading

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Kewei, E-mail: drzkw@126.com; Chai, Yuesheng; Fu, Jiahui

2015-12-15

Resonant-mode based cantilevers are an important type of acoustic wave based mass-sensing devices. In this work, the governing vibration equation of a bi-layer resonant-mode based cantilever attached with concentrated mass is established by using a modal analysis method. The effects of resonance modes and mass loading conditions on nodes and mass sensitivity of the cantilever were theoretically studied. The results suggested that the node did not shift when concentrated mass was loaded on a specific position. Mass sensitivity of the cantilever was linearly proportional to the square of the point displacement at the mass loading position for all the resonancemore » modes. For the first resonance mode, when mass loading position x{sub c} satisfied 0 < x{sub c} < ∼ 0.3l (l is the cantilever beam length and 0 represents the rigid end), mass sensitivity decreased as the mass increasing while the opposite trend was obtained when mass loading satisfied ∼0.3l ≤ x{sub c} ≤ l. Mass sensitivity did not change when concentrated mass was loaded at the rigid end. This work can provide scientific guidance to optimize the mass sensitivity of a resonant-mode based cantilever.« less

The alteration of T790M between 19 del and L858R in NSCLC in the course of EGFR-TKIs therapy: a literature-based pooled analysis.

PubMed

Liang, Hengrui; Pan, Zhenkui; Wang, Wei; Guo, Chengye; Chen, Difei; Zhang, Jianrong; Zhang, Yiyin; Tang, Shiyan; He, Jianxing; Liang, Wenhua

2018-04-01

Treatment-naive epidermal growth factor receptor (EGFR) T790M mutation is more inclined to coexist with L858R than with 19 del in non-small cell lung cancer (NSCLC) patients. However, EGFR-tyrosine kinase inhibitors (EGFR-TKIs) might alter this status. We sought to compare the prevalence of T790M upon acquired resistance to EGFR-TKIs between 19 del and L858R by assembling all existing data. Electronic databases were comprehensively searched for eligible studies. The primary endpoint was the odds ratio (OR) of T790M mutation in NSCLC co-existing with L858R mutation and 19 del upon resistance to first-generation EGFR-TKIs. A random effects model was used. Stratified analysis was performed based on study type (retrospective and prospective), race (Asians and Caucasians) and sample type (tissue and plasma). A total of 25 studies involving 1,770 patients were included. The overall T790M existent rate was 45.25%. Post-resistance T790M was more frequent in 19 del than in L858R mutated patients (53% vs. 36%; OR 1.87; P<0.001). All outcomes of subgroup and overall analyses were similar. In contrast, we re-analyzed the previous meta-analysis, finding that the pooled rate of pretreatment T790M was 14% and 22% in 19 del and L858R respectively (OR 0.59; P<0.001). The increase of T790M rate was 2.79-fold in 19 del and only 0.63-fold in L858R in the course of EGFR-TKIs therapy. Opposite to the situation of de novo T790M, it was observed that T790M was more frequent in exon 19 deletion than in L858R among patients with acquired resistance to EGFR-TKIs. The difference in T790M alteration between 19 del and L858R encourages development of detection or treatment strategies for the specific resistance mechanism.

Three-in-one resonance tube for harmonic series sound wave experiments

NASA Astrophysics Data System (ADS)

Jaafar, Rosly; Nazihah Mat Daud, Anis; Ali, Shaharudin; Kadri Ayop, Shahrul

2017-07-01

In this study we constructed a special three-in-one resonance tube for a harmonic series sound waves experiment. It is designed for three different experiments: both-open-end, one-closed-end and both-closed-end tubes. The resonance tube consists of a PVC conduit with a rectangular hole, rubber tube, plastic stopper with an embedded microphone and a plastic stopper. The resonance tube is utilized with visual analyser freeware to detect, display and measure the resonance frequencies for each harmonic series. The speeds of sound in air, v, are determined from the gradient of the 2(L+e) versus n fn-1 , 4(L+e) versus n fn-1 and 2L versus n fn-1 graphs for both-open-end, one-closed-end and both-closed-end tubes, respectively. The compatibility of a resonance tube for a harmonic series experiment is determined by comparing the experimental and standard values of v. The use of a resonance tube produces accurate results for v within a 1.91% error compared to its standard value. It can also be used to determine the values of end correction, e, in both-open-end and one-closed-end tubes. The special resonance tube can also be used for the values of n for a harmonic series experiment in the three types of resonance tubes: both-open-end, one-closed-end and both-closed-end tubes.

Therapeutic drug monitoring of posaconazole in hematology adults under posaconazole prophylaxis: influence of food intake.

PubMed

Eiden, C; Meniane, J C; Peyrière, H; Eymard-Duvernay, S; Le Falher, G; Ceballos, P; Fegueux, N; Cociglio, M; Reynes, J; Hillaire-Buys, D

2012-02-01

Posaconazole (PCZ) is given at 200 mg three times daily as a fungal prophylaxis in neutropenic hematologic malignancy patients. A relationship between exposure, plasma concentration, and efficacy is suggested. The objectives of this prospective study were to analyze the PCZ plasma concentration in hematology adults at high risk of developing invasive fungal infections (IFIs), and factors that could have an impact on the PCZ plasma concentration. PCZ plasma concentrations were measured after 2, 7, 10, 14, and 21 days of PCZ prophylaxis. Factors such as gender, age, body weight, posology, treatment duration, mucositis, proton pump inhibitor (PPI) use, and food intake were studied. Sixty-three patients were included, with a median age of 52 years (range 17-70) and a median weight of 75 kg (range 47-150). The median PCZ plasma concentration of the 63 patients ranged from 0.42 to 0.48 mg/L. At day 2, 30% of PCZ plasma concentration were under 0.35 mg/L, and at day 7, 74% were <0.70 mg/L. PCZ plasma concentrations were not affected by gender, age, body weight, or treatment duration. We found that food intake had a high influence on PCZ plasma concentrations (p = 0.0049). PCZ was well tolerated. One patient has developed a probable IFI, probably related to a low exposure to PCZ. PCZ therapeutic drug monitoring (TDM) is essential in order to early detect patients with low concentrations, to assess the etiology of such results, and to decide on the treatment strategy to apply.

Measurement of Exhaust Emissions from Diesel-Powered Forklifts during Operations in Ammunition Storage Magazines.

DTIC Science & Technology

1985-02-01

Sprague, Jerry Krohn, and Kevin White of the U.S. Army Defense Ammunition Center and School, whose cooperation and practical assistance assured a...16:5’ 4𔃺 288 W. 1 699 807 1606 1672’ 17:10 420 298 3." 779 822 1165 927, 17:70 440: 652 7.7 1189 1285 601 6 17:50~ 460’ ** **** **** ** Waer , 556 .6

Regional drought shifts (1710-2010) in East Central Asia and linkages with atmospheric circulation recorded in tree-ring δ18O

NASA Astrophysics Data System (ADS)

Xu, Guobao; Liu, Xiaohong; Trouet, Valerie; Treydte, Kerstin; Wu, Guoju; Chen, Tuo; Sun, Weizhen; An, Wenling; Wang, Wenzhi; Zeng, Xiaomin; Qin, Dahe

2018-04-01

Drought occurrence and duration in central Asia are of important socioeconomic, ecological, and geophysical significance and have received increasing research attention in recent years. Understanding long-term drought trends and their driving forces require reliable records of past drought variability with broad spatial representativeness. Here, we compiled four tree-ring δ18O records from eastern central Asia (ECA) and composited them into a drought-sensitive proxy to explore regional ECA moisture variations over the past 301 years (1710-2010 CE). A robust regional standardized precipitation-evapotranspiration index (SPEI) reconstruction was established based on the tree-ring cellulose δ18O fractionation mechanism and statistically significant proxy-climate relationships. We identified prominent droughts in 1710-1770, 1810-1830, and the beginning of the twenty-first century, and a regime shift to a persistently wet period from the 1880s to 2000. Our reconstruction reveals the impact of drought and pluvial patterns on the decline of Zhungar Empire, and on historical agricultural and socio-economical activities, including increased migration into ECA during the 1770-1800 pluvial. Our findings also suggest that wet conditions in the twentieth century in ECA were related to a strengthening of the westerly circulation and thus shed light on large-scale atmospheric circulation dynamics in central Asia.

An analytical formula for the longitudinal resonance frequencies of a fluid-filled crack

NASA Astrophysics Data System (ADS)

Maeda, Y.; Kumagai, H.

2013-12-01

The fluid-filled crack model (Chouet, 1986, JGR) simulates the resonances of a rectangular crack filled with an inviscid fluid embedded in a homogeneous isotropic elastic medium. The model demonstrates the existence of a slow wave, known as the crack wave, that propagates along the solid-fluid interfaces. The wave velocity depends on the crack stiffness. The model has been used to interpret the peak frequencies of long-period (LP) and very long period (VLP) seismic events at various volcanoes (Chouet and Matoza, 2013, JVGR). Up to now, crack model simulations have been performed using the finite difference (Chouet, 1986) and boundary integral (Yamamoto and Kawakatsu, 2008, GJI) methods. These methods require computationally extensive procedures to estimate the complex frequencies of crack resonance modes. Establishing an easier way to calculate the frequencies of crack resonances would help understanding of the observed frequencies. In this presentation, we propose a simple analytical formula for the longitudinal resonance frequencies of a fluid-filled crack. We first evaluated the analytical expression proposed by Kumagai (2009, Encyc. Complex. Sys. Sci.) through a comparison of the expression with the peak frequencies computed by a 2D version of the FDM code of Chouet (1986). Our comparison revealed that the equation of Kumagai (2009) shows discrepancies with the resonant frequencies computed by the FDM. We then modified the formula as fmL = (m-1)a/[2L(1+2ɛmLC)1/2], (1) where L is the crack length, a is the velocity of sound in the fluid, C is the crack stiffness, m is a positive integer defined such that the wavelength of the normal displacement on the crack surface is 2L/m, and ɛmL is a constant that depends on the longitudinal resonance modes. Excellent fits were obtained between the peak frequencies calculated by the FDM and by Eq. (1), suggesting that this equation is suitable for the resonant frequencies. We also performed 3D FDM computations of the longitudinal mode resonances. The peak frequencies computed by the FDM are well fitted by Eq. (1). The best-fit ɛmL values are different from those for 2D and depend on W/L, where W is the crack width. Eq. (1) shows that fmL is a simple analytical function of a/L and C given m and W/L. This enables simple and rapid interpretations of the source processes of LP events, including estimation of the fluid properties and crack geometries as well as identification of the resonance modes of the individual peak frequencies. LP events at volcanoes often exhibit peak frequency variations. In such cases, the frequency variations can be easily converted to variations in the fluid properties and crack geometries. We showed that Eq. (1) is consistent with the analytical solution for an infinite crack given by Ferrazzini and Aki (1987, JGR). Although a theoretical derivation of Eq. (1) was not obtained yet, Eq. (1) is consistent with the frequencies expected from the wavelengths of the fluid pressure variation.

Radiative rates and electron impact excitation rate coefficients for Ne-like selenium, Se XXV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, K.; Chen, C.Y., E-mail: chychen@fudan.edu.cn; Huang, M.

2011-07-15

In this article we report calculations of energy levels, radiative rates, electron impact collision strengths, and effective collision strengths for transitions among the 241 fine-structure levels arising from 2l{sup 8} and 2l{sup 7}n{sup '}l{sup '} (n{sup '{<=}}6 and l{sup '{<=}}n{sup '}-1) configurations of Ne-like Se XXV using the Flexible Atomic Code. Energy levels and radiative rates are calculated within the relativistic configuration-interaction method. Direct excitation collision strengths are calculated using the relativistic distorted-wave approximation and high-energy collision strengths are obtained in the relativistic plane-wave approximation. Resonance contributions through the relevant Na-like doubly-excited configurations 2l{sup 7}n'l'n''l'' (3{<=}n'{<=}7, l'{<=}n'-1, n'{<=}n''{<=}50, and l''{<=}8)more » are explicitly taken into account via the independent-process and isolated-resonance approximation using distorted waves. Resonant stabilizing transitions and possibly important radiative decays from the resonances toward low-lying autoionizing levels are considered. In addition, the resonance contributions from Na-like 2l{sup 6}3l'3l'''n''' (n'''=3-6) configurations are included and found to be predominant for many transitions among the singly-excited states in Ne-like Se XXV. We present the radiative rates, oscillator strengths, and line strengths for all electric dipole, magnetic dipole, electric quadrupole, magnetic quadrupole, electric octopole, and magnetic octopole transitions among the 241 levels. The effective collision strengths are reported for all 28920 transitions among the 241 levels over a wide temperature range up to 10 keV. To assess the reliability and accuracy of the present collisional data, we have performed a 27-state close-coupling calculation, employing the Dirac R-matrix theory. The results from the close-coupling calculation and the independent-process calculation for the identical target states are found to be in good agreement. - Highlights: {yields} Radiative and collisional atomic data are presented for the lowest 241 fine-structure levels in Ne-like Se. {yields} Calculations are performed using the FAC package. {yields} Resonances enhance significantly a large amount of transitions. {yields} Radiative damping effects are significant for many transitions. {yields} Close-coupling effects are small in Ne-like Se.« less

Nano-polarization-converter based on magnetic plasmon resonance excitation in an L-shaped slot antenna.

PubMed

Yang, Jing; Zhang, Jiasen

2013-04-08

We propose a nano-polarization-converter made of a resonant L-shaped slot antenna in a gold film and study its optical properties using the finite-difference time-domain method. Phase retardation between the fast and slow axes of the nano-polarization-converter originates from the simultaneous excitation of both single-surface first-order magnetic plasmon resonance mode and second-order magnetic plasmon resonance mode at the working wavelength. By adjusting the size of the slot antenna, which is still much smaller than the wavelength, the working wavelength can be tuned within a large wavelength range.

Resynthesis of muscle glycogen after soccer specific performance examined by 13C-magnetic resonance spectroscopy in elite players.

PubMed

Zehnder, M; Rico-Sanz, J; Kühne, G; Boutellier, U

2001-05-01

The purpose of this study was to examine using 13C-magnetic resonance spectroscopy whether muscle glycogen (Gly) utilized during a simulation of a fatiguing soccer match followed by repeated sprints would be resynthesized during the next 24 h while players consumed their habitual diet. A group of 12 elite young players [mean age 17.5 (SD 0.8) years, mean body mass 68.9 (SD 6.6) kg, mean height 177.0 (SD 5.4) cm] participated in the study. Average muscle Gly content before the simulation was 134 (SD 16) mmol.(kg wet mass)-1 and decreased during the test (P < 0.001) to 80 (SD 29) mmol.(kg wet mass)-1. The value had increased (P < 0.01) to 122 (SD 33) mmol.(kg wet mass)-1 24 h later but it was not significantly different from the value obtained before the soccer test. Dietary analysis of the food intake during the 24 h after the running test revealed that players consumed an average of 2,681 (SD 970) kcal.day-1. Mean daily protein, fat, and carbohydrate (CHO) intakes were 85 (SD 29), 99 (SD 44), and 327 (SD 116) g, respectively. The mean amounts of CHO intake normalised to body mass were 4.8 (SD 1.8) g.(kg body mass)-1. In conclusion, the results of this study showed that despite a CHO intake of less than 5 g.(kg body mass)-1 the habitual diet of soccer players might be sufficient to replenish in 24 h the muscle Gly utilized during soccer specific performance. However, cumulative deficits of about 10% in Gly replenishment as found in the present study might provoke decrements in performance. Thus, players should pay attention to their habitual diets and add more carbohydrates to replenish their daily deficits and perhaps increase their basal levels of intake.

Correlation between Clinical Features and Magnetic Resonance Imaging Findings in Lumbar Disc Prolapse.

PubMed

Thapa, S S; Lakhey, R B; Sharma, P; Pokhrel, R K

2016-05-01

Magnetic resonance imaging is routinely done for diagnosis of lumbar disc prolapse. Many abnormalities of disc are observed even in asymptomatic patient.This study was conducted tocorrelate these abnormalities observed on Magnetic resonance imaging and clinical features of lumbar disc prolapse. A This prospective analytical study includes 57 cases of lumbar disc prolapse presenting to Department of Orthopedics, Tribhuvan University Teaching Hospital from March 2011 to August 2012. All patientshad Magnetic resonance imaging of lumbar spine and the findings regarding type, level and position of lumbar disc prolapse, any neural canal or foraminal compromise was recorded. These imaging findings were then correlated with clinical signs and symptoms. Chi-square test was used to find out p-value for correlation between clinical features and Magnetic resonance imaging findings using SPSS 17.0. This study included 57 patients, with mean age 36.8 years. Of them 41(71.9%) patients had radicular leg pain along specific dermatome. Magnetic resonance imaging showed 104 lumbar disc prolapselevel. Disc prolapse at L4-L5 and L5-S1 level constituted 85.5%.Magnetic resonance imaging findings of neural foramina compromise and nerve root compression were fairly correlated withclinical findings of radicular pain and neurological deficit. Clinical features and Magnetic resonance imaging findings of lumbar discprolasehad faircorrelation, but all imaging abnormalities do not have a clinical significance.

Multiple-Barrier Resonant Tunneling Structures for Application in a Microwave Generator Stabilized by Microstrip Resonator

DTIC Science & Technology

2000-06-23

conductivity ( NDC ) effects in double barrier resonant tunneling structures (DBRTS) prove the extremely fast frequency response of charge transport (less...UNCLASSIFIED Defense Technical Information Center Compilation Part Notice ADP013131 TITLE: Multiple-Barrier Resonant Tunneling Structures for...Institute Multiple-barrier resonant tunneling structures for application in a microwave generator stabilized by microstrip resonator S. V. Evstigneev, A. L

The Bauschinger and Hardening Effects on Residual Stresses in an Autofrettaged Thick-Walled Cylinder

DTIC Science & Technology

1984-06-01

8217Large Caliber Weapon3 Systems Labrra-ory 1ý’ NUBE OF PAGES Dover, 1.7)70 14 "NITOING AGENCY N XME: A ADDRF!SS(Ir -ditI.. fromI Controlling Office. IS...US ARMY AMCCOM COMMANDER ATTN: DRSMC-LC(D) 1 US ARMY TANK-AUTMV COMD DRSMC-LCE(D) I ATTN: DRSTA-RC DRSMC-LCM(D) ( BLDC 321) 1 WARREN, MI 48090 DRSMC-LCS

Fixed Target Comparative Analysis

DTIC Science & Technology

1991-12-01

and WhiteO lo APPROVED FOR PUBLIC RELEASE, DISTR6I1770N UNLIMITED. 92-18060 Rome Laboratory Air Force Systems Command Griffiss Air Force Base, NY...13441-5700 024 r This report has been reviewed by the Rome Laboratory Public Affairs Office (PA) and is releasable to the National Technical Information...Service (NTIS). At NTIS it will be releasable to the general public , including foreign nations. RL-TR-91-417 has been reviewed and is approved for

[Byzantine therapeutics in the Ottoman world].

PubMed

Varella, E A

1999-01-01

The medical literature of the greek speaking ottoman world was deeply influenced by its byzantine heritage: the major authors were copied and commented, while practical manuals containing recipes and therapies - the iatrosophia- kept being enlarged with useful information. Furthermore, during the first centuries hospitals closely followed the models of their glorious past in what concerns architecture, scientific level, means and targets. In fact, only the years after 1770 rely on occidental academic knowledge and adopt modern conceptions.

Resonance and Capture of Jupiter Comets

NASA Astrophysics Data System (ADS)

Koon, W. S.; Lo, M. W.; Marsden, J. E.; Ross, S. D.

A number of Jupiter family comets such as Oterma and Gehrels 3 make a rapid transition from heliocentric orbits outside the orbit of Jupiter to heliocentric orbits inside the orbit of Jupiter and vice versa. During this transition, the comet can be captured temporarily by Jupiter for one to several orbits around Jupiter. The interior heliocentric orbit is typically close to the 3:2 resonance while the exterior heliocentric orbit is near the 2:3 resonance. An important feature of the dynamics of these comets is that during the transition, the orbit passes close to the libration points L_1 and L_2, two of the equilibrium points for the restricted three-body problem for the Sun-Jupiter system. Studying the libration point invariant manifold structures for L_1 and L_2 is a starting point for understanding the capture and resonance transition of these comets. For example, the recently discovered heteroclinic connection between pairs of unstable periodic orbits (one around the L_1 and the other around L_2) implies a complicated dynamics for comets in a certain energy range. Furthermore, the stable and unstable invariant manifold `tubes' associated to libration point periodic orbits, of which the heteroclinic connections are a part, are phase space conduits transporting material to and from Jupiter and between the interior and exterior of Jupiter's orbit.

Transient Resonance Raman Spectroscopy of a Light-Driven Sodium-Ion-Pump Rhodopsin from Indibacter alkaliphilus.

PubMed

Kajimoto, Kousuke; Kikukawa, Takashi; Nakashima, Hiroki; Yamaryo, Haruki; Saito, Yuta; Fujisawa, Tomotsumi; Demura, Makoto; Unno, Masashi

2017-05-04

Sodium-ion-pump rhodopsin (NaR) is a microbial rhodopsin that transports Na + during its photocycle. Here we explore the photocycle mechanism of NaR from Indibacter alkaliphilus with transient absorption and transient resonance Raman spectroscopy. The transient absorption data indicate that the photocycle of NaR is K (545 nm) → L (490 nm)/M (420 nm) → O 1 (590 nm) → O 2 (560 nm) → NaR, where the L and M are formed as equilibrium states. The presence of K, L, M, and O intermediates was confirmed by the resonance Raman spectra with 442 and 532 nm excitation. The main component of the transient resonance Raman spectra was due to L which contains a 13-cis retinal protonated Schiff base. The presence of an enhanced hydrogen out-of-plane band as well as its sensitivity to the H/D exchange indicate that the retinal chromophore is distorted near the Schiff base region in L. Moreover, the retinal Schiff base of the L state forms a hydrogen bond that is stronger than that of the dark state. These observations are consistent with a Na + pumping mechanism that involves a proton transfer from the retinal Schiff base to a key aspartate residue (Asp116 in Krokinobacter eikastus rhodopsin 2) in the L/M states.

l-Tryptophan Radical Cation Electron Spin Resonance Studies: Connecting Solution-derived Hyperfine Coupling Constants with Protein Spectral Interpretations

PubMed Central

Connor, Henry D.; Sturgeon, Bradley E.; Mottley, Carolyn; Sipe, Herbert J.; Mason, Ronald P.

2009-01-01

Fast-flow electron spin resonance (ESR) spectroscopy has been used to detect a free radical formed from the reaction of l-tryptophan with Ce4+ in an acidic aqueous environment. Computer simulations of the ESR spectra from l-tryptophan and several isotopically modified forms strongly support the conclusion that the l-tryptophan radical cation has been detected by ESR for the first time. The hyperfine coupling constants (HFCs) determined from the well-resolved isotropic ESR spectra support experimental and computational efforts to understand l-tryptophan's role in protein catalysis of oxidation-reduction processes. l-tryptophan HFCs facilitated the simulation of fast-flow ESR spectra of free radicals from two related compounds, tryptamine and 3-methylindole. Analysis of these three compounds' β-methylene hydrogen HFC data along with equivalent l-tyrosine data has led to a new computational method that can distinguish between these two amino acid free radicals in proteins without dependence on isotope labeling, electron nuclear double resonance or high-field ESR. This approach also produces geometric parameters (dihedral angles for the β-methylene hydrogens) which should facilitate protein site assignment of observed l-tryptophan radicals as has been done for l-tyrosine radicals. PMID:18433127

Sensitivity optimization in whispering gallery mode optical cylindrical biosensors

NASA Astrophysics Data System (ADS)

Khozeymeh, F.; Razaghi, M.

2018-01-01

Whispering-gallery-mode resonances propagated in cylindrical resonators have two angular and radial orders of l and i. In this work, the higher radial order whispering-gallery-mode resonances, (i = 1 - 4), at a fixed l are examined. The sensitivity of theses resonances is analysed as a function of the structural parameters of the cylindrical resonator like different radii and refractive index of composed material of the resonator. A practical application where cylindrical resonators are used for the measurement of glucose concentration in water is presented as a biosensor demonstrator. We calculate the wavelength shifts of the WG1-4, in several glucose/water solutions, with concentrations spanning from 0.0% to 9.0.% (weight/weight). Improved sensitivity can be achieved using multi-WGM cylindrical resonators with radius of R = 100 μm and resonator composed material of MgF 2 with refractive index of nc = 1.38. Also the effect of polarization on sensitivity is considered for all four WGMs. The best sensitivity of 83.07 nm/RIU for the fourth WGM with transverse magnetic polarization, is reported. These results propose optimized parameters aimed to fast designing of cylindrical resonators as optical biosensors, where both the sensitivity and the geometries can be optimized.

Tunable Resonance Coupling in Single Si Nanoparticle-Monolayer WS2 Structures.

PubMed

Lepeshov, Sergey; Wang, Mingsong; Krasnok, Alex; Kotov, Oleg; Zhang, Tianyi; Liu, He; Jiang, Taizhi; Korgel, Brian; Terrones, Mauricio; Zheng, Yuebing; Alú, Andrea

2018-05-16

Two-dimensional semiconducting transition metal dichalcogenides (TMDCs) are extremely attractive materials for optoelectronic applications in the visible and near-infrared range. Coupling these materials to optical nanocavities enables advanced quantum optics and nanophotonic devices. Here, we address the issue of resonance coupling in hybrid exciton-polariton structures based on single Si nanoparticles (NPs) coupled to monolayer (1L)-WS 2 . We predict a strong coupling regime with a Rabi splitting energy exceeding 110 meV for a Si NP covered by 1L-WS 2 at the magnetic optical Mie resonance because of the symmetry of the mode. Further, we achieve a large enhancement in the Rabi splitting energy up to 208 meV by changing the surrounding dielectric material from air to water. The prediction is based on the experimental estimation of TMDC dipole moment variation obtained from the measured photoluminescence spectra of 1L-WS 2 in different solvents. An ability of such a system to tune the resonance coupling is realized experimentally for optically resonant spherical Si NPs placed on 1L-WS 2 . The Rabi splitting energy obtained for this scenario increases from 49.6 to 86.6 meV after replacing air by water. Our findings pave the way to develop high-efficiency optoelectronic, nanophotonic, and quantum optical devices.

Characteristics of pitch angle distributions of relativistic electrons under the interaction with Pc5 waves in the inner magnetosphere

NASA Astrophysics Data System (ADS)

Kamiya, K.; Seki, K.; Saito, S.; Amano, T.; Yoshizumi, M.

2017-12-01

Radial transport of relativistic electrons in the inner magnetosphere has been considered as one of acceleration mechanisms of the outer radiation belt electrons and can be driven by the drift resonance with ULF waves in the Pc5 frequency range. The maximum changes of the electron in the radial distance (L) due to the drift resonance depend on the electron energy, pitch angle, and Pc5 wave structure. Those dependences are expected to form the characteristic pitch angle distributions (PADs) as a function of L and electron energy. In this study, we investigate PADs of relativistic electrons due to the drift resonance with a monochromatic Pc5 wave by using two simulation models of the inner magnetosphere: GEMSIS-Ring Current (RC) and GEMSIS-Radiation Belt (RB) models. The GEMSIS-RB simulations calculate guiding center trajectories of relativistic electrons in electric and magnetic fields obtained from the GEMSIS-RC model, which simulates a monochromatic Pc5 wave propagation in the inner magnetosphere. The results show the characteristic PADs depending on the energy and L, which is explicable with the pitch angle dependence of resonance conditions. At a fixed location, those PADs can change from pancake (90°peaked) to butterfly (two peaks in oblique PAs) distributions as the transport by the monochromatic Pc5 wave progresses. These butterfly distributions are seen in the L range where electrons with lower PAs satisfy the resonance condition. It is also found that the lower PA electron with a fixed magnetic moment can be transported deeper inside because of the PA changes to larger values through the adiabatic transport, which enables them to satisfy the efficient resonance condition in wider L range compared to the 90 degrees PA electrons.

Heteroclinic connections between periodic orbits and resonance transitions in celestial mechanics

NASA Astrophysics Data System (ADS)

Koon, Wang Sang; Lo, Martin W.; Marsden, Jerrold E.; Ross, Shane D.

2000-06-01

In this paper we apply dynamical systems techniques to the problem of heteroclinic connections and resonance transitions in the planar circular restricted three-body problem. These related phenomena have been of concern for some time in topics such as the capture of comets and asteroids and with the design of trajectories for space missions such as the Genesis Discovery Mission. The main new technical result in this paper is the numerical demonstration of the existence of a heteroclinic connection between pairs of periodic orbits: one around the libration point L1 and the other around L2, with the two periodic orbits having the same energy. This result is applied to the resonance transition problem and to the explicit numerical construction of interesting orbits with prescribed itineraries. The point of view developed in this paper is that the invariant manifold structures associated to L1 and L2 as well as the aforementioned heteroclinic connection are fundamental tools that can aid in understanding dynamical channels throughout the solar system as well as transport between the ``interior'' and ``exterior'' Hill's regions and other resonant phenomena.

Phase-Array Approach to Optical Whispering Gallery Modulators

NASA Technical Reports Server (NTRS)

Strekalov, Dmitry

2010-01-01

This technology leverages the well-defined orbital number of a whispering gallery modulator (WGM) to expand the range of applications for such resonators. This property rigidly connects the phase variation of the field in this mode with the azimuthal angle between the coupling locations. A WGM with orbital momentum L has exactly L instant nodes around the circumference of the WGM resonator supporting such a mode. Therefore, in two locations separated by the arc alpha, the phase difference of such a field will be equal to phi= alpha L. Coupling the field out of such locations, and into a balanced interferometer, once can observe a complete constructive or distractive interference (or have any situation in between) depending on the angle alpha. Similarly, a mode L + delta L will pick up the phase phi + alpha delta L. In all applications of a WGM resonator as a modulator, the orbital numbers for the carrier and sidebands are different, and their differences delta L are known (usually, but not necessarily, delta L = 1). Therefore, the choice of the angle alpha, and of the interferometer arms difference, allows one to control the relative phase between different modes and to perform the conversion, separation, and filtering tasks necessary.

Another look at zonal flows: Resonance, shearing, and frictionless saturation

NASA Astrophysics Data System (ADS)

Li, J. C.; Diamond, P. H.

2018-04-01

We show that shear is not the exclusive parameter that represents all aspects of flow structure effects on turbulence. Rather, wave-flow resonance enters turbulence regulation, both linearly and nonlinearly. Resonance suppresses the linear instability by wave absorption. Flow shear can weaken the resonance, and thus destabilize drift waves, in contrast to the near-universal conventional shear suppression paradigm. Furthermore, consideration of wave-flow resonance resolves the long-standing problem of how zonal flows (ZFs) saturate in the limit of weak or zero frictional drag, and also determines the ZF scale. We show that resonant vorticity mixing, which conserves potential enstrophy, enables ZF saturation in the absence of drag, and so is effective at regulating the Dimits up-shift regime. Vorticity mixing is incorporated as a nonlinear, self-regulation effect in an extended 0D predator-prey model of drift-ZF turbulence. This analysis determines the saturated ZF shear and shows that the mesoscopic ZF width scales as LZ F˜f3 /16(1-f ) 1 /8ρs5/8l03 /8 in the (relevant) adiabatic limit (i.e., τckk‖2D‖≫1 ). f is the fraction of turbulence energy coupled to ZF and l0 is the base state mixing length, absent ZF shears. We calculate and compare the stationary flow and turbulence level in frictionless, weakly frictional, and strongly frictional regimes. In the frictionless limit, the results differ significantly from conventionally quoted scalings derived for frictional regimes. To leading order, the flow is independent of turbulence intensity. The turbulence level scales as E ˜(γL/εc) 2 , which indicates the extent of the "near-marginal" regime to be γL<εc , for the case of avalanche-induced profile variability. Here, εc is the rate of dissipation of potential enstrophy and γL is the characteristic linear growth rate of fluctuations. The implications for dynamics near marginality of the strong scaling of saturated E with γL are discussed.

Moving for Employment: Are Hispanics Less Geographically Mobile than Anglos and Blacks

DTIC Science & Technology

1989-01-01

and odmntify by block numfber) F0EL GRO9 SU-GOU Hispanic, mobility,’ equal employment opportunity I TIACT (Contir on ril t iif necessary and identify b...development work unit R 1770-MP012, Equal Employment Opportunity Enhancement. Its purpose was to determine whether cultural differences exist in...Codes -- -vanaxi/or Dist Special v SUMMARY Problem ’n- Each Navy activity establishes equal employment opportunity (EEO) goals propor- tional to the

The Marc Dax (1770-1837)/Paul Broca (1824-1880) Controversy over Priority in Science: Left Hemisphere Specificity for Seat of Articulate Language and for Lesions that Cause Aphemia

ERIC Educational Resources Information Center

Buckingham, Hugh W.

2006-01-01

One of the most fascinating and frustrating issues in the priority of discovery in science is over just who, for the first time, went on record in the public forum, either orally at a conference or through a published communication, proclaiming that the faculty of articulate human speech was located in the left, not the right, cortical hemisphere.…

Does Shyness Vary According to Attained Social Roles? Trends Across Age Groups in a Large British Sample.

PubMed

Van Zalk, Nejra; Lamb, Michael E; Jason Rentfrow, Peter

2017-12-01

The current study investigated (a) how a composite measure of shyness comprising introversion and neuroticism relates to other well-known constructs involving social fears, and (b) whether mean levels of shyness vary for men and women depending on the adoption of various social roles. Study 1 used a sample of 211 UK participants aged 17-70 (64% female; M age  = 47.90). Study 2 used data from a large cross-sectional data set with UK participants aged 17-70 (N target  = 552,663; 64% female; M age  = 34.19 years). Study 1 showed that shyness measured as a composite of introversion and neuroticism was highly correlated with other constructs involving social fears. Study 2 indicated that, controlling for various sociodemographic variables, females appeared to have higher levels, whereas males appeared to have lower levels of shyness. Males and females who were in employment had the lowest shyness levels, whereas those working in unskilled jobs had the highest levels and people working in sales the lowest levels of shyness. Participants in relationships had lower levels of shyness than those not in relationships, but parenthood was not associated with shyness. Mean levels of shyness are likely to vary according to adopted social roles, gender, and age. © 2016 Wiley Periodicals, Inc.

Reduction in blood pressure and serum lipids by lycosome formulation of dark chocolate and lycopene in prehypertension

PubMed Central

Petyaev, Ivan M; Dovgalevsky, Pavel Y; Chalyk, Natalia E; Klochkov, Victor; Kyle, Nigel H

2014-01-01

Twenty-nine healthy volunteers aged 47–69 years old were randomly assigned to a 28-day oral intake of different dark chocolate (DC) formulations. The main group received daily 30 g of proprietary lycopene-containing (L-tug) lycosome formulation of DC with enhanced bioavailability of cocoa flavanols. Two control groups daily consumed either 30 g of regular DC alone or along with 7 mg of lycopene, which corresponds to the amount of lycopene ingested with L-tug formulation. It was found that L-tug was more efficient in reducing diastolic blood pressure (mean value of −6.22 mmHg, 95% CI: 5.00, 8.00) when compared with the regular DC group (−3.00 mmHg, P < 0.05) or the group which ingested the DC and lycopene as two separate formulations (mean reduction of −4 mmHg, 95% CI: 2.47, 6.00, P = 0.0262). Only marginal superiority for L-tug formulation in the reduction in systolic blood pressure was seen. However, the L-tug formulation was the only formulation of DC which affected serum lipids. There was a reduction in total cholesterol (from median 228.00 mg/dL [95% CI: 206.2, 242.5] to 187.00 mg/dL [95% CI: 166.2, 202.2, P < 0.05]) with corresponding decline of low-density lipoprotein (LDL) cholesterol (from a median of 166.00 mg/dL [95% CI: 130.8, 177.0] to 151.00 mg/dL [95% CI: 122.8, 167.4; P < 0.05]) at the end of the intervention period. Similar decline was seen in serum triglycerides (P < 0.05). Serum high-density lipoprotein (HDL) cholesterol, glucose levels, and C-reactive protein (CRP) values remained statistically unchanged in all study groups throughout the intervention period. A superior biological activity of the L-tug lycosome formulation of DC extending beyond its antihypertensive effect to lipid-lowering ability opens up new possibilities for the use of DC for health purposes helping to reduce daily caloric intake without compromising on the health benefits of DC consumption. PMID:25493193

Behavioral and Biological Effects of Resonant Electromagnetic Absorption in Rats.

DTIC Science & Technology

1976-11-01

for 23-550 MHz, biological phantom materials to simulate tissue properties, monopole -above-ground radiation chamber, design of a waveguide slot array...Resonant Electromagnetic Power Absorption in Rats" L T OF FTCTIF S A,’L i .LIS SFigure Pa 1 A photograiph of the monopole -above-gruund radiation...and mice without ground effects (L/2b = 3.25 where 21Tb is the "average" circumference of the animals) ........ .................... ... 20 8

Etude de la formation de resonances electroniques et de leur role dans la fragmentation neutre de molecules d'interet biologique

NASA Astrophysics Data System (ADS)

Lepage, Martin

1998-12-01

Cette these est presentee a la Faculte de medecine de l'Universite de Sherbrooke en vue de l'obtention du grade de Ph.D. en Radiobiologie. Elle contient des resultats experimentaux enregistres avec un spectrometre d'electrons a haute resolution. Ces resultats portent sur la formation de resonances electroniques en phase condensee et de differents canaux pour leur decroissance. En premier lieu, nous presentons des mesures d'excitations vibrationnelles de l'oxygene dilue en matrice d'argon pour des energies des electrons incidents de 1 a 20 eV. Les resultats suggerent que le temps de vie des resonances de l'oxygene est modifie par la densite d'etats d'electrons dans la bande de conduction de l'argon. Nous presentons aussi des spectres de pertes d'energie d'electrons des molecules de tetrahydrofuranne (THF) et d'acetone. Dans les deux cas, la position en energie des pertes associees aux excitations vibrationnelles est en excellent accord avec les resultats trouves dans la litterature. Les fonctions d'excitation de ces modes revelent la presence de plusieurs nouvelles resonances electroniques. Nous comparons les resonances du THF et celles de la molecule de cyclopentane en phase gazeuse. Nous proposons une origine commune aux resonances ce qui implique qu'elles ne sont pas necessairement attribuees a l'excitation des electrons non-apparies de l'oxygene du THF. Nous proposons une nouvelle methode basee sur la spectroscopie par pertes d'energie des electrons pour detecter la production de fragments neutres qui demeurent a l'interieur d'un film mince condense a basse temperature. Cette methode se base sur la detection des excitations electroniques du produit neutre. Nous presentons des resultats de la production de CO dans un film de methanol. Le taux de production de CO en fonction de l'energie incidente des electrons est calibre en termes d'une section efficace totale de diffusion des electrons. Les resultats indiquent une augmentation lineaire du taux de production de CO en fonction de l'epaisseur du film et de la dose d'electrons incidente sur le film. Ces donnees experimentales cadrent dans un modele simple ou un electron cause la fragmentation de la molecule sans reaction avec les molecules avoisinantes. Le mecanisme propose pour la fragmentation unimoleculaire du methanol est la formation de resonances qui decroissent dans un etat electronique excite. Nous suggerons l'action combinee de la presence d'un trou dans une orbitale de coeur du methanol et de la presence de deux electrons dans la premiere orbitale vide pour expliquer la dehydrogenation complete du methanol pour des energies des electrons entre 8 et 18 eV. Pour des energies plus grandes, la fragmentation par l'intermediaire de l'ionisation de la molecule a deja ete suggeree. La methode de detection des etats electroniques offre une alternative a la detection des excitations vibrationnelles puisque les spectres de pertes d'energie des electrons sont congestionnes dans cette region d'energie pour les molecules polyatomiques.

Phosphodiester content measured in human liver by in vivo 31 P MR spectroscopy at 7 tesla.

PubMed

Purvis, Lucian A B; Clarke, William T; Valkovič, Ladislav; Levick, Christina; Pavlides, Michael; Barnes, Eleanor; Cobbold, Jeremy F; Robson, Matthew D; Rodgers, Christopher T

2017-12-01

Phosphorus ( 31 P) metabolites are emerging liver disease biomarkers. Of particular interest are phosphomonoester and phosphodiester (PDE) "peaks" that comprise multiple overlapping resonances in 31 P spectra. This study investigates the effect of improved spectral resolution at 7 Tesla (T) on quantifying hepatic metabolites in cirrhosis. Five volunteers were scanned to determine metabolite T 1 s. Ten volunteers and 11 patients with liver cirrhosis were scanned at 7T. Liver spectra were acquired in 28 min using a 16-channel 31 P array and 3D chemical shift imaging. Concentrations were calculated using γ-adenosine-triphosphate (γ-ATP) = 2.65 mmol/L wet tissue. T 1 means ± standard deviations: phosphatidylcholine 1.05 ± 0.28 s, nicotinamide-adenine-dinucleotide (NAD + ) 2.0 ± 1.0 s, uridine-diphosphoglucose (UDPG) 3.3 ± 1.4 s. Concentrations in healthy volunteers: α-ATP 2.74 ± 0.11 mmol/L wet tissue, inorganic phosphate 2.23 ± 0.20 mmol/L wet tissue, glycerophosphocholine 2.34 ± 0.46 mmol/L wet tissue, glycerophosphoethanolamine 1.50 ± 0.28 mmol/L wet tissue, phosphocholine 1.06 ± 0.16 mmol/L wet tissue, phosphoethanolamine 0.77 ± 0.14 mmol/L wet tissue, NAD + 2.37 ± 0.14 mmol/L wet tissue, UDPG 2.00 ± 0.22 mmol/L wet tissue, phosphatidylcholine 1.38 ± 0.31 mmol/L wet tissue. Inorganic phosphate and phosphatidylcholine concentrations were significantly lower in patients; glycerophosphoethanolamine concentrations were significantly higher (P < 0.05). We report human in vivo hepatic T 1 s for phosphatidylcholine, NAD + , and UDPG for the first time at 7T. Our protocol allows high signal-to-noise, repeatable measurement of metabolite concentrations in human liver. The splitting of PDE into its constituent peaks at 7T may allow more insight into changes in metabolism. Magn Reson Med 78:2095-2105, 2017. © 2017 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. © 2017 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine.

Resonant Raman Auger effect in Xe

NASA Astrophysics Data System (ADS)

Armen, Brad; Levin, Jon

1996-05-01

The L_3-M_4,5M_4,5 spectator Auger process in xenon is investigated from the viewpoint of radiationless resonant Raman scattering. Calculations for spectator cross sections and electron spectra are presented as functions of incident photon energy near the L3 edge. These calculations are based on the lowest-order scattering theory(T. Åberg, Phys. Scr. T41, 71 (1992).) which has proved successful in the interpretation of argon ion yields coincident with K-L_2,3L_2,3 decay.footnote G. B. Armen, J. C. Levin, and I. A. Sellin , Phys Rev A 53, 1 (1996).

Ln3+-Catalyzed Alcoholysis of Organophosphates: New Methodology for the Catalytic Transformation of Phosphorus Pesticides and CW Agents

DTIC Science & Technology

2007-03-14

1770. 9. Graham T. T. Gibson, Mark F. Mohamed, Alexei A. Neverov and R. S. Brown*, “ Potentiometric titration of metal ions in ethanol.” Inorganic...81, 495-504. 2 . Graham T. T. Gibson, Mark F. Mohamed, Alexei A. Neverov and R. S. Brown*, “ Potentiometric titration of metal ions in ethanol...necessary to understand the determination of pH in these anhydrous solvents, and then to undertake detailed studies of titration of metal

Freedom’s Gate: The Southern Insurgency in the American Revolution, 1770-1781

DTIC Science & Technology

2014-01-01

of Loyalist militia units raised in the South. 3 Excepting Ferguson, a Scot serving in the British army, all of them were Americans. His ultimatum to...believed the backcountry of the Carolinas occupied by "a Sett of the most lowest vile crew breathing- Scot -Irish Presbyterians from the North of Ireland...informally in houses, hams, and often out in open. After 1666, the British army, given lists of Scots not attending Anglican services, literally began

Reduction of a Class of Fox-Wright PSI Functions for Certain Rational Parameters

DTIC Science & Technology

1995-01-01

a. REPORT unclassified b. ABSTRACT unclassified c . THIS PAGE unclassified Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 1...evidently with Lambert (1758). Numerous other investigators studied them, notably Lagrange (1770), Heymann (1887), Capelli (1892), Ramanujan (circa...per unit time, that can be transmitted over the channel is called the capacity C and is de ned by C = limsupn!1 log2 n q jSnj : (6:1) The original de

Identification of Methanococcus Jannaschii Proteins in 2-D Gel Electrophoresis Patterns by Mass Spectrometry

DOE R&D Accomplishments Database

Liang, X.

1998-06-10

The genome of Methanococcus jannaschii has been sequenced completely and has been found to contain approximately 1,770 predicted protein-coding regions. When these coding regions are expressed and how their expression is regulated, however, remain open questions. In this work, mass spectrometry was combined with two-dimensional gel electrophoresis to identify which proteins the genes produce under different growth conditions, and thus investigate the regulation of genes responsible for functions characteristic of this thermophilic representative of the methanogenic Archaea.

SUGGEL: A Program Suggesting the Orbital Angular Momentum of a Neutron Resonance from the Magnitude of its Neutron Width

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oh, S.Y.

2001-02-02

The SUGGEL computer code has been developed to suggest a value for the orbital angular momentum of a neutron resonance that is consistent with the magnitude of its neutron width. The suggestion is based on the probability that a resonance having a certain value of g{Gamma}{sub n} is an l-wave resonance. The probability is calculated by using Bayes' theorem on the conditional probability. The probability density functions (pdf's) of g{Gamma}{sub n} for up to d-wave (l=2) have been derived from the {chi}{sup 2} distribution of Porter and Thomas. The pdf's take two possible channel spins into account. This code ismore » a tool which evaluators will use to construct resonance parameters and help to assign resonance spin. The use of this tool is expected to reduce time and effort in the evaluation procedure, since the number of repeated runs of the fitting code (e.g., SAMMY) may be reduced.« less

Glottalized resonants in NLe kepmxcin (Thompson River Salish)

NASA Astrophysics Data System (ADS)

Shaw, Patricia A.; Campbell, Fiona M.; Ehrhardt, Flora

2005-04-01

This study examines properties of glottalized resonants (/m', n', l', y', w'/) in NLe?kepmxcin, a Northern Interior Salish language, both comparing them with their plain counterparts (m, n, l, y, w) and considering contextual factors as defined by word, syllable, and prominence positions. Despite the relative cross-linguistic rarity of glottalized resonants, they are of considerable theoretical interest given that several recent studies [e.g., Bird and Caldecott, Proceedings of the 10th AICSST (in press)] indicate that their articulatory and acoustic realization may vary significantly across languages and contexts. Of particular relevance to the present study is Carlson, Esling, and Harris' [UMOPL 17, 58-71 (2004)] claim that in NLe?kepmxcin ``glottalized resonants are a sequential combination of the resonant plus [glottal stop]'' [pg. 64]. Based on the analysis of glottalized resonants in this study, it appears that the picture is more complex than consistent post-glottalization. Of special interest are glottalized resonants in word-initial position, both because this class is seriously under-represented in the previous literature, and because its characteristics challenge Carlson, Esling, and Harris' sequencing generalization. Understanding the organization of glottalized resonants will help clarify both sequential and markedness issues in NLe?kepmxcin phonology. [Work supported by SSHRC.

Synthesis, characterization and properties of L-arginine-passivated silver nanocolloids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sunatkari, A. L., E-mail: ashok.sunatkari@rediffmail.com; Talwatkar, S. S.; Tamgadge, Y. S.

2016-05-06

We investigate the effect of L-arginine-surface passivation on localised surface plasmon resonance (LSPR), size and stability of colloidal Silver Nanoparticles (AgNPs) synthesized by chemical reduction method. The surface Plasmon resonance absorption peak of AgNPs shows blue shift with the increase in L-arginine concentration. Transmission electron microscopy (TEM) analysis confirmed that the average size of AgNPs reduces from 10 nm to 6 nm as the concentration of L-Arginine increased from 1 to 5 mM. The X-ray diffraction study (XRD) confirmed the formation face-centred cubic (fcc) structured AgNPs. FT-IR studies revealed strong bonding between L-arginine functional groups and AgNPs.

Lumbar spine disc height and curvature responses to an axial load generated by a compression device compatible with magnetic resonance imaging

NASA Technical Reports Server (NTRS)

Kimura, S.; Steinbach, G. C.; Watenpaugh, D. E.; Hargens, A. R.

2001-01-01

STUDY DESIGN: Axial load-dependent changes in the lumbar spine of supine healthy volunteers were examined using a compression device compatible with magnetic resonance imaging. OBJECTIVE: To test two hypotheses: Axial loading of 50% body weight from shoulder to feet in supine posture 1) simulates the upright lumbar spine alignment and 2) decreases disc height significantly. SUMMARY OF BACKGROUND DATA: Axial compression on the lumbar spine has significantly narrowed the lumbar dural sac in patients with sciatica, neurogenic claudication or both. METHODS: Using a device compatible with magnetic resonance imaging, the lumbar spine of eight young volunteers, ages 22 to 36 years, was axially compressed with a force equivalent to 50% of body weight, approximating the normal load on the lumbar spine in upright posture. Sagittal lumbar magnetic resonance imaging was performed to measure intervertebral angle and disc height before and during compression. RESULTS: Each intervertebral angle before and during compression was as follows: T12-L1 (-0.8 degrees +/- 2.5 degrees and -1.5 degrees +/- 2.6 degrees ), L1-L2 (0.7 degrees +/- 1.4 degrees and 3.3 degrees +/- 2.9 degrees ), L2-L3 (4.7 degrees +/- 3.5 degrees and 7.3 degrees +/- 6 degrees ), L3-L4 (7.9 degrees +/- 2.4 degrees and 11.1 degrees +/- 4.6 degrees ), L4-L5 (14.3 degrees +/- 3.3 degrees and 14.9 degrees +/- 1.7 degrees ), L5-S1 (25.8 degrees +/- 5.2 degrees and 20.8 degrees +/- 6 degrees ), and L1-S1 (53.4 degrees +/- 11.9 degrees and 57.3 degrees +/- 16.7 degrees ). Negative values reflect kyphosis, and positive values reflect lordosis. A significant difference between values before and during compression was obtained at L3-L4 and L5-S1. There was a significant decrease in disc height only at L4-L5 during compression. CONCLUSIONS: The axial force of 50% body weight in supine posture simulates the upright lumbar spine morphologically. No change in intervertebral angle occurred at L4-L5. However, disc height at L4-L5 decreased significantly during compression.

Plasma pharmacokinetics of once-daily abacavir- and lamivudine-containing regimens and week 96 efficacy in HIV-infected Thai children.

PubMed

Bunupuradah, Torsak; Punyahotra, Passorn; Cressey, Tim R; Srimuan, Amornrat; Thammajaruk, Narukjaporn; Sophonphan, Jiratchaya; Sriheara, Chulalak; Burger, David M; Puthanakit, Thanyawee; Ananworanich, Jintanat

2015-07-01

Abacavir and lamivudine are approved for once-daily use in HIV-infected adults. Limited pharmacokinetic (PK) data for abacavir and lamivudine in children are available. A crossover study to compare PK of once- versus twice-daily abacavir and lamivudine was conducted in virologically suppressed HIV-infected Thai children aged <18years, with bodyweight of at least 14 kg, HIV RNA <50 copies/mL and HLA-B*5701 negative. Abacavir and lamivudine daily doses by bodyweight were 300 and 150 mg for 14-<20 kg, 450 and 300 mg for 20-<25 kg, and 600 and 300 mg for ≥25 kg, respectively. Originator abacavir and lamivudine scored tablets were administered. Intensive PK sampling was performed after 14 days of each dose. PK parameters were determined using non-compartmental analysis. Thirty children (57% male) were enrolled, 10 per weight band. Median (IQR) age was 8.8 (6.6-11.3) years and bodyweight was 21.9 (19.2-30.6) kg. The geometric means (GM) AUC0-24 of once- and twice-daily abacavir were 14.43 and 10.65 mg.h/L, respectively. The geometric mean ratio (GMR) of AUC0-24 for once- versus twice-daily abacavir dosing was 1.36 [90% confidence interval (CI) 1.11-1.66]. The GM AUC0-24 of once- and twice-daily lamivudine were 17.70 and 18.11 mg.h/L, respectively. The GMR of AUC0-24 for once- versus twice-daily lamivudine dosing was 0.98 (90% CI 0.84-1.14). At 96 weeks, 90% had HIV RNA <50 copies/mL and there were no serious adverse events. Abacavir exposure was greater with once-daily dosing, while lamivudine once- and twice-daily exposures were bioequivalent. Once-daily abacavir and lamivudine using weight-band dosing is a treatment option for children.

Three-Body Recombination near a Narrow Feshbach Resonance in Li 6

NASA Astrophysics Data System (ADS)

Li, Jiaming; Liu, Ji; Luo, Le; Gao, Bo

2018-05-01

We experimentally measure and theoretically analyze the three-atom recombination rate, L3, around a narrow s -wave magnetic Feshbach resonance of Li 6 - Li 6 at 543.3 G. By examining both the magnetic field dependence and, especially, the temperature dependence of L3 over a wide range of temperatures from a few μ K to above 200 μ K , we show that three-atom recombination through a narrow resonance follows a universal behavior determined by the long-range van der Waals potential and can be described by a set of rate equations in which three-body recombination proceeds via successive pairwise interactions. We expect the underlying physical picture to be applicable not only to narrow s wave resonances, but also to resonances in nonzero partial waves, and not only at ultracold temperatures, but also at much higher temperatures.

Tunable absorption enhancement in electric split-ring resonators-shaped graphene arrays

NASA Astrophysics Data System (ADS)

Liu, Lin; Chen, Jiajia; Zhou, Zigang; Yi, Zao; Ye, Xin

2018-04-01

In this paper, we propose a wavelength-tunable absorber consisting of electric split-ring resonators (eSRRs)-shaped graphene arrays deposited on a SiO2/Si substrate in the far-infrared and terahertz regions. The simulation results exhibit that two resonance modes are supported by the structure. In terms of the resonance at longer wavelength, the light absorption declines while the period a or length L increases. However, absorption contrarily improves with enlargement of incident angle under the transverse magnetic (TM) polarization. And in terms of resonance at shorter wavelengths, absorption enhances with increasing length L and incident angle θ. Generally, the light absorption enhances with Fermi level E F of graphene, accompanied by blue shift. The aforementioned results unquestionably provide a distinctive source of inspiration for how to design and manufacture devices related to absorption such as filters, spatial light modulator and sensors.

Method for measuring lead concentrations in blood

DOEpatents

Nogar, Nicholas S.

2001-01-01

Method for measuring lead concentrations in blood. The present invention includes the use of resonant laser ablation to analyze .ltoreq.1 .mu.L (or equivalent mass) samples of blood for lead content. A typical finger prick, for example, yields about 10 .mu.L. Solid samples may also readily be analyzed by resonant laser ablation. The sample is placed on a lead-free, electrically conducting substrate and irradiated with a single, focused laser beam which simultaneously vaporizes, atomizes, and resonantly ionizes an analyte of interest in a sample. The ions are then sorted, collected and detected using a mass spectrometer.

Conditions and phase shift of fluid resonance in narrow gaps of bottom mounted caissons

NASA Astrophysics Data System (ADS)

Zhu, Da-tong; Wang, Xing-gang; Liu, Qing-jun

2017-12-01

This paper studies the viscid and inviscid fluid resonance in gaps of bottom mounted caissons on the basis of the plane wave hypothesis and full wave model. The theoretical analysis and the numerical results demonstrate that the condition for the appearance of fluid resonance in narrow gaps is kh=(2 n+1)π ( n=0, 1, 2, 3, …), rather than kh= nπ ( n=0, 1, 2, 3, …); the transmission peaks in viscid fluid are related to the resonance peaks in the gaps. k and h stand for the wave number and the gap length. The combination of the plane wave hypothesis or the full wave model with the local viscosity model can accurately determine the heights and the locations of the resonance peaks. The upper bound for the appearance of fluid resonance in gaps is 2 b/ L<1 (2 b, grating constant; L, wave length) and the lower bound is h/ b≤1. The main reason for the phase shift of the resonance peaks is the inductive factors. The number of resonance peaks in the spectrum curve is dependent on the ratio of the gap length to the grating constant. The heights and the positions of the resonance peaks predicted by the present models agree well with the experimental data.

Embodiment and Emotional Memory in First vs. Second Language

PubMed Central

Baumeister, Jenny C.; Foroni, Francesco; Conrad, Markus; Rumiati, Raffaella I.; Winkielman, Piotr

2017-01-01

Language and emotions are closely linked. However, previous research suggests that this link is stronger in a native language (L1) than in a second language (L2) that had been learned later in life. The present study investigates whether such reduced emotionality in L2 is reflected in changes in emotional memory and embodied responses to L2 in comparison to L1. Late Spanish/English bilinguals performed a memory task involving an encoding and a surprise retrieval phase. Facial motor resonance and skin conductance (SC) responses were recorded during encoding. The results give first indications that the enhanced memory for emotional vs. neutral content (EEM effect) is stronger in L1 and less present in L2. Furthermore, the results give partial support for decreased facial motor resonance and SC responses to emotional words in L2 as compared to L1. These findings suggest that embodied knowledge involved in emotional memory is associated to increased affective encoding and retrieval of L1 compared to L2. PMID:28386240

Production of vector resonances at the LHC via WZ-scattering: a unitarized EChL analysis

NASA Astrophysics Data System (ADS)

Delgado, R. L.; Dobado, A.; Espriu, D.; Garcia-Garcia, C.; Herrero, M. J.; Marcano, X.; Sanz-Cillero, J. J.

2017-11-01

In the present work we study the production of vector resonances at the LHC by means of the vector boson scattering WZ → WZ and explore the sensitivities to these resonances for the expected future LHC luminosities. We are assuming that these vector resonances are generated dynamically from the self interactions of the longitudinal gauge bosons, W L and Z L , and work under the framework of the electroweak chiral Lagrangian to describe in a model independent way the supposedly strong dynamics of these modes. The properties of the vector resonances, mass, width and couplings to the W and Z gauge bosons are derived from the inverse amplitude method approach. We implement all these features into a single model, the IAM-MC, adapted for MonteCarlo, built in a Lagrangian language in terms of the electroweak chiral Lagrangian and a chiral Lagrangian for the vector resonances, which mimics the resonant behavior of the IAM and provides unitary amplitudes. The model has been implemented in MadGraph, allowing us to perform a realistic study of the signal versus background events at the LHC. In particular, we have focused our study on the pp → WZjj type of events, discussing first on the potential of the hadronic and semileptonic channels of the final WZ, and next exploring in more detail the most clear signals. These are provided by the leptonic decays of the gauge bosons, leading to a final state with ℓ 1 + ℓ 1 - ℓ 2 + νjj, ℓ = e, μ, having a very distinctive signature, and showing clearly the emergence of the resonances with masses in the range of 1.5-2.5 TeV, which we have explored.

Distributed meandering waveguides (DMWs) for novel photonic circuits (Conference Presentation)

NASA Astrophysics Data System (ADS)

Dag, Ceren B.; Anil, Mehmet Ali; Serpengüzel, Ali

2017-05-01

Meandering waveguide distributed feedback structures are novel integrated photonic lightwave and microwave circuit elements. Meandering waveguide distributed feedback structures with a variety of spectral responses can be designed for a variety of lightwave and microwave circuit element functions. Distributed meandering waveguide (DMW) structures [1] show a variety of spectral behaviors with respect to the number of meandering loop mirrors (MLMs) [2] used in their composition as well as their internal coupling constants (Cs). DMW spectral behaviors include Fano resonances, coupled resonator induced transparency (CRIT), notch, add-drop, comb, and hitless filters. What makes the DMW special is the self-coupling property intrinsic to the DMW's nature. The basic example of DMW's nature is motivated through the analogy between the so-called symmetric meandering resonator (SMR), which consists of two coupled MLMs, and the resonator enhanced Mach-Zehnder interferometer (REMZI) [3]. A SMR shows the same spectral characteristics of Fano resonances with its self-coupling property, similar to the single, distributed and binary self coupled optical waveguide (SCOW) resonators [4]. So far DMWs have been studied for their electric field intensity, phase [5] and phasor responses [6]. The spectral analysis is performed using the coupled electric field analysis and the generalization of single meandering loop mirrors to multiple meandering distributed feedback structures is performed with the transfer matrix method. The building block of the meandering waveguide structures, the meandering loop mirror (MLM), is the integrated analogue of the fiber optic loop mirrors. The meandering resonator (MR) is composed of two uncoupled MLM's. The meandering distributed feedback (MDFB) structure is the DFB of the MLM. The symmetric MR (SMR) is composed of two coupled MLM's, and has the characteristics of a Fano resonator in the general case, and tunable power divider or tunable hitless filter in special cases. The antisymmetric MR (AMR) is composed of two coupled MLM's. The AMR has the characteristics of an add-drop filter in the general case, and coupled resonator induced transparency (CRIT) filter in a special case. The symmetric MDFB (SMDFB) is composed of multiple coupled MLM's. The antisymmetric MDFB (AMDFB) is composed of multiple coupled MLM's. The SMDFB and AMDFB can be utilized as band-pass, Fano, or Lorentzian filters, or Rabi splitters. Distributed meandering waveguide elements with extremely rich spectral and phase responses can be designed with creative combinations of distributed meandering waveguides structures for various novel photonic circuits. References [1 ] C. B. Dağ, M. A. Anıl, and A. Serpengüzel, "Meandering Waveguide Distributed Feedback Lightwave Circuits," J. Lightwave Technol, vol. 33, no. 9, pp. 1691-1702, May 2015. [2] N. J. Doran and D. Wood, "Nonlinear-optical loop mirror," Opt. Lett. vol. 13, no. 1, pp. 56-58, Jan. 1988. [3] L. Zhou and A. W. Poon, "Fano resonance-based electrically reconfigurable add-drop filters in silicon microring resonator-coupled Mach-Zehnder interferometers," Opt. Lett. vol. 32, no. 7, pp. 781-783, Apr. 2007. [4] Z. Zou, L. Zhou, X. Sun, J. Xie, H. Zhu, L. Lu, X. Li, and J. Chen, "Tunable two-stage self-coupled optical waveguide resonators," Opt. Lett. vol. 38, no. 8, pp. 1215-1217, Apr. 2013. [5] C. B. Dağ, M. A. Anıl, and A. Serpengüzel, "Novel distributed feedback lightwave circuit elements," in Proc. SPIE, San Francisco, 2015, vol. 9366, p. 93660A. [6] C. B. Dağ, M. A. Anıl, and A. Serpengüzel, "Meandering Waveguide Distributed Feedback Lightwave Elements: Phasor Diagram Analysis," in Proc. PIERS, Prague, 1986-1990 (2015).

Occupied and unoccupied electronic structures of an L-cysteine film studied by core-absorption and resonant photoelectron spectroscopies

NASA Astrophysics Data System (ADS)

Kamada, M.; Hideshima, T.; Azuma, J.; Yamamoto, I.; Imamura, M.; Takahashi, K.

2016-04-01

Unoccupied and occupied electronic structures of an L-cysteine film have been studied by absorption and resonant photoelectron spectroscopies. Core absorptions at S-L, C-K, N-K, and O-K levels indicate that the lower unoccupied states are predominantly composed of oxygen-2p, carbon-2p, and sulfur-4s+3d orbitals, while higher unoccupied states may be attributed dominantly to nitrogen-np (n ≥ 3), oxygen-np (n ≥ 3), and sulfur-ns+md (n ≥ 4, m ≥ 3) orbitals. Resonant photoelectron spectra at S-L23 and O-K levels indicate that the highest occupied state is originated from sulfur-3sp orbitals, while oxygen-2sp orbitals contribute to the deeper valence states. The delocalization lifetimes of the oxygen-1s and sulfur-2p excited states are estimated from a core-hole clock method to be about 9 ± 1 and 125 ± 25 fs, respectively.

Occupied and unoccupied electronic structures of an L-cysteine film studied by core-absorption and resonant photoelectron spectroscopies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kamada, M., E-mail: kamada@cc.saga-u.ac.jp; Hideshima, T.; Azuma, J.

2016-04-15

Unoccupied and occupied electronic structures of an L-cysteine film have been studied by absorption and resonant photoelectron spectroscopies. Core absorptions at S-L, C-K, N-K, and O-K levels indicate that the lower unoccupied states are predominantly composed of oxygen-2p, carbon-2p, and sulfur-4s+3d orbitals, while higher unoccupied states may be attributed dominantly to nitrogen-np (n ≥ 3), oxygen-np (n ≥ 3), and sulfur-ns+md (n ≥ 4,  m ≥ 3) orbitals. Resonant photoelectron spectra at S-L{sub 23} and O-K levels indicate that the highest occupied state is originated from sulfur-3sp orbitals, while oxygen-2sp orbitals contribute to the deeper valence states. The delocalization lifetimesmore » of the oxygen-1s and sulfur-2p excited states are estimated from a core-hole clock method to be about 9 ± 1 and 125 ± 25 fs, respectively.« less

Resonances and thresholds in the Rydberg-level population of multiply charged ions at solid surfaces

NASA Astrophysics Data System (ADS)

Nedeljković, Lj. D.; Nedeljković, N. N.

1998-12-01

We present a theoretical study of resonances and thresholds, two specific features of Rydberg-state formation of multiply charged ions (Z=6, 7, and 8) escaping a solid surface at intermediate velocities (v~1 a.u.) in the normal emergence geometry. The resonances are recognized in pronounced maxima of the experimentally observed population curves of Ar VIII ions for resonant values of the principal quantum number n=nres=11 and for the angular momentum quantum numbers l=1 and 2. Absence of optical signals in detectors of beam-foil experiments for n>nthr of S VI and Cl VII ions (with l=0, 1, and 2) and Ar VIII for l=0 is interpreted as a threshold phenomenon. An interplay between resonance and threshold effects is established within the framework of quantum dynamics of the low angular momentum Rydberg-state formation, based on a generalization of Demkov-Ostrovskii's charge-exchange model. In the model proposed, the Ar VIII resonances appear as a consequence of electron tunneling in the very vicinity of the ion-surface potential barrier top and at some critical ion-surface distances Rc. The observed thresholds are explained by means of a decay mechanism of ionic Rydberg states formed dominantly above the Fermi level EF of a solid conduction band. The theoretically predicted resonant and threshold values, nres and nthr of the principal quantum number n, as well as the obtained population probabilities Pnl=Pnl(v,Z), are in sufficiently good agreement with all available experimental findings.

High-Q Superconducting Coplanar Waveguide Resonators for Integration into Molecule Ion Traps

DTIC Science & Technology

2010-05-01

V12C (3.13) 4 and We = V12 (3.14) 4 w 2 L’ finally yielding 2Wm R Q = wo m - w0L= woRC, (3.15) where wo = 1/ vLC is the resonant frequency of the...small. The primary challenge with simulating the microresonators was refining the mesh while remaining under memory limits of the modeling computer. It

Carbon K-edge spectra of carbonate minerals.

PubMed

Brandes, Jay A; Wirick, Sue; Jacobsen, Chris

2010-09-01

Carbon K-edge X-ray spectroscopy has been applied to the study of a wide range of organic samples, from polymers and coals to interstellar dust particles. Identification of carbonaceous materials within these samples is accomplished by the pattern of resonances in the 280-320 eV energy region. Carbonate minerals are often encountered in the study of natural samples, and have been identified by a distinctive resonance at 290.3 eV. Here C K-edge and Ca L-edge spectra from a range of carbonate minerals are presented. Although all carbonates exhibit a sharp 290 eV resonance, both the precise position of this resonance and the positions of other resonances vary among minerals. The relative strengths of the different carbonate resonances also vary with crystal orientation to the linearly polarized X-ray beam. Intriguingly, several carbonate minerals also exhibit a strong 288.6 eV resonance, consistent with the position of a carbonyl resonance rather than carbonate. Calcite and aragonite, although indistinguishable spectrally at the C K-edge, exhibited significantly different spectra at the Ca L-edge. The distinctive spectral fingerprints of carbonates provide an identification tool, allowing for the examination of such processes as carbon sequestration in minerals, Mn substitution in marine calcium carbonates (dolomitization) and serpentinization of basalts.

The morphometric study of l3-L4 and L4-L5 lumbar spine in Asian population using magnetic resonance imaging: feasibility analysis for transpsoas lumbar interbody fusion.

PubMed

Yusof, Mohd Imran; Nadarajan, Eswaran; Abdullah, Mohd Shafie

2014-06-15

Cross-sectional study on the measurement of relevant magnetic resonance imaging parameters in 100 patients presented for lumbar spine assessment. To determine anatomical position of lumbar plexus and major blood vessels in relation to vertebral body and anterior edge of psoas muscle at L3-L4 and L4-L5 and to define the safe working zone for transpsoas approach for lumbar fusion. Lateral transpsoas lumbar interbody fusion has been shown to be safe and provides alternative for lumbar fusion. However, proximity of neurovascular structures may not allow a safe passage for this procedure in the Asian population. Relevant parameters were measured from axial magnetic resonance images and analyzed, including the psoas muscle and vertebrae endplate diameters, lumbar plexus and psoas muscle distance, lumbar plexus and vertebra body distance, and vena cava to the anterior vertebrae body diameters. The mean anteroposterior diameters of the right and left psoas muscle ranged from 44.0 to 58.6 mm and 44.8 to 54.0 mm, respectively. The mean anteroposterior diameters of vertebra endplate of L3, L4, and L5 were 38.2 mm, 39.3 mm, and 41.4 mm, respectively. The mean distance of posterior border of vena cava from the vertebra body was 4.5 mm at L3-L4 and 14.1 mm at L4-L5. L3-L4 fusion is feasible at both sides in both sexes; however, at L4-L5 level, the procedure is feasible only on the left side. The safe working zone for transpsoas approach to lumbar spine is significantly narrower at L4-L5 in both sexes. Anterior edge of psoas muscle can be used as a reliable guide to locate lumbar plexus within psoas muscle. N/A.

Gene encoding a novel invertase from a xerophilic Aspergillus niger strain and production of the enzyme in Pichia pastoris.

PubMed

Veana, Fabiola; Fuentes-Garibay, José Antonio; Aguilar, Cristóbal Noé; Rodríguez-Herrera, Raúl; Guerrero-Olazarán, Martha; Viader-Salvadó, José María

2014-09-01

β-Fructofuranosidases or invertases (EC 3.2.1.26) are enzymes that are widely used in the food industry, where fructose is preferred over sucrose, because it is sweeter and does not crystallize easily. Since Aspergillus niger GH1, an xerophilic fungus from the Mexican semi-desert, has been reported to be an invertase producer, and because of the need for new enzymes with biotechnological applications, in this work, we describe the gene and amino acid sequence of the invertase from A. niger GH1, and the use of a synthetic gene to produce the enzyme in the methylotrophic yeast Pichia pastoris. In addition, the produced invertase was characterized biochemically. The sequence of the invertase gene had a length of 1770 bp without introns, encodes a protein of 589 amino acids, and presented an identity of 93% and 97% with invertases from Aspergillus kawachi IFO 4308 and A. niger B60, respectively. A 4.2 L culture with the constructed recombinant P. pastoris strain showed an extracellular and periplasmic invertase production at 72 h induction of 498 and 3776 invertase units (U), respectively, which corresponds to 1018 U/L of culture medium. The invertase produced had an optimum pH of 5.0, optimum temperature of 60 °C, and specific activity of 3389 U/mg protein, and after storage for 96 h at 4 °C showed 93.7% of its activity. This invertase could be suitable for producing inverted sugar used in the food industry. Copyright © 2014 Elsevier Inc. All rights reserved.

Potential effects of surface coal mining on the hydrology of the upper Otter Creek-Pasture Creek Area, Moorehead coal field, southeastern Montana

USGS Publications Warehouse

McClymonds, N.E.; Moreland, J.A.

1988-01-01

The combined upper Otter Creek-Pasture Creek area, south of Ashland, Montana, contains large reserves of Federal coal for potential lease sale. A hydrologic study was conducted in the area to describe existing hydrologic systems and generalized groundwater quality, to assess potential effects of surface mining on local water resources, and to evaluate the potential for reclamation of those water resources. Principal aquifers are coal beds and sandstone in the upper Tongue River Member of the Fort Union Formation (Paleocene age), and sand and gravel in alluvium (Pleistocene and Holocene age). Hydraulic conductivity determined from aquifer tests was about 0.004 to 16 ft/d for coal or sandstone aquifers and 1 to 290 ft/d for alluvial aquifers. Dissolved-solids concentrations in water from bedrock ranged from 1,160 to 4,390 mg/L. In alluvium, the concentrations were 1,770 to 12,600 mg/L. Surface water is available from interrupted flow along downstream reaches of Otter and Pasture Creeks, from stock ponds, and from springs. Most stock ponds are dry by midsummer. Mining of coal in the Anderson, Dietz, and Canyon beds would lower the potentiometric surface within coal and sandstone aquifers. Alluvium along Otter Creek, its main tributaries, and Pasture Creek would be removed at the mines. Planned structuring of the spoils and reconstruction of alluvial aquifers could minimize downstream changes in water quality. Although mining would alter the existing hydrologic systems and destroy several shallow wells and stock ponds, alternative water supplies are available. (USGS)

ICRF heating in a straight, helically symmetric stellarator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jaeger, E.F.; Weitzner, H.; Batchelor, D.B.

1987-07-01

Experimental observations of direct ion cyclotron resonant frequency (ICRF) heating at fundamental ion cyclotron resonance on the L-2 stellarator have stimulated interest in the theoretical basis for such heating. In this paper, global solutions for the ICRF wave fields in a helically symmetric, straight stellarator are calculated in the cold plasma limit. The component of the wave electric field parallel to B-vector is assumed zero. Helical symmetry allows Fourier decomposition in the longitudinal (z) direction. The two remaining partial differential equations in tau and phi identical to THETA - hz (h is the helical pitch) are solved by finite differencing.more » Energy absorption and antenna impedance are calculated from an ad hoc collision model. Results for parameters typical of the L-2 and Advanced Toroidal Facility (ATF) stellarators show that direct resonant absorption of the fundamental ion cyclotron resonance occurs mainly near the plasma edge. The magnitude of the absorption is about half that for minority heating at the two-ion hybrid resonance.« less

Search for massive resonances decaying into WW, WZ or ZZ bosons in proton-proton collisions at $$ \\sqrt{s}=13 $$ TeV

DOE PAGES

Sirunyan, A. M.; Tumasyan, A.; Adam, W.; ...

2017-03-30

We present a search for new massive resonances decaying to WW, WZ or ZZ bosons in l nu quark anti-quark and quark anti-quark quark anti-quark final states. Our results are based on data corresponding to an integrated luminosity of 2.3-2.7 inverse femtobarns recorded in proton-proton collisions atmore » $$\\sqrt{s} = $$ 13 TeV with the CMS detector at the LHC. Decays of spin-1 and spin-2 resonances into two vector bosons are sought in the mass range 0.6-4.0 TeV. No significant excess over the standard model background is observed. Combining the results of the l nu quark anti-quark and quark anti-quark quark anti-quark final states, cross section and mass exclusion limits are set for models that predict heavy spin-1 and spin-2 resonances. Furthermore, this is the first search for a narrow-width spin-2 resonance at $$\\sqrt{s} = $$ 13 TeV.« less

Simulation of High-Resolution Magnetic Resonance Images on the IBM Blue Gene/L Supercomputer Using SIMRI

DOE PAGES

Baum, K. G.; Menezes, G.; Helguera, M.

2011-01-01

Medical imaging system simulators are tools that provide a means to evaluate system architecture and create artificial image sets that are appropriate for specific applications. We have modified SIMRI, a Bloch equation-based magnetic resonance image simulator, in order to successfully generate high-resolution 3D MR images of the Montreal brain phantom using Blue Gene/L systems. Results show that redistribution of the workload allows an anatomically accurate 256 3 voxel spin-echo simulation in less than 5 hours when executed on an 8192-node partition of a Blue Gene/L system.

Simulation of High-Resolution Magnetic Resonance Images on the IBM Blue Gene/L Supercomputer Using SIMRI.

PubMed

Baum, K G; Menezes, G; Helguera, M

2011-01-01

Medical imaging system simulators are tools that provide a means to evaluate system architecture and create artificial image sets that are appropriate for specific applications. We have modified SIMRI, a Bloch equation-based magnetic resonance image simulator, in order to successfully generate high-resolution 3D MR images of the Montreal brain phantom using Blue Gene/L systems. Results show that redistribution of the workload allows an anatomically accurate 256(3) voxel spin-echo simulation in less than 5 hours when executed on an 8192-node partition of a Blue Gene/L system.

PD-1/PD-L1 inhibitor screening of caffeoylquinic acid compounds using surface plasmon resonance spectroscopy.

PubMed

Han, Ya; Gao, Yaning; He, Tian; Wang, Daidong; Guo, Ning; Zhang, Xiaotian; Chen, Shizhong; Wang, Hong

2018-04-15

Following the FDA approval of three monoclonal antibodies of PD-1/PD-L1, this pathway has become a promising target for cancer treatment. Currently small-molecule inhibitors have not been extensively investigated, and appropriate screening methods for such inhibitors are urgently required. In this study, surface plasmon resonance (SPR) technology was used to evaluate the affinity and competitive inhibition of nine caffeoylquinic acid compounds (CQAs) against PD-1/PD-L1. As a result, four small molecules including 1-CQA, 3-CQA, 4-CQA and 5-CQA were determined as PD-1/PD-L1 inhibitors. This study provided an efficient method for screening small-molecule inhibitors targeting PD-1/PD-L1 pathway. Copyright © 2018. Published by Elsevier Inc.

This Land is Ours. The Shaping of Xhosa Resistance to European Expansion Along the Cape Colony’s Eastern Frontier, 1770-1820

DTIC Science & Technology

1992-12-01

ings when he says that Theal, the pioneer, the founder of South African historiography, did more than anyone else to estab- lish a tradition of...to Tshawe, the mythical founder of a unified Xhosa polity . However, political fragmentation and armed conflict among the heirs 13 J. B. Peires, The...Years 1803, 1804, 1805 and 1806. Translated by A. Plumptre. 2 vols. Cape Town: Van Riebeeck Society, 1928-1930. Lucas, Thomas J. The Zulus and the British

Vertical Alignment of Single-Walled Carbon Nanotubes on Nanostructure Fabricated by Atomic Force Microscope

DTIC Science & Technology

2007-05-01

SWNTs by blending them with liquid crystal,7 assem- bling SWNT films by Langmuir - Blodgett methods,8 and chemical assembly of SWNTs on a large substrate...Ulman, A. An Introduction to Ultrathin Organic Films from Langmuir - Blodgett to Self-Assembly. Academic: New York, (1991). [10] Moon, J.H., Shin, J.W...Fang, J. Langmuir , 16, 2651, (2000). [8] FT-IR data (Bruker IFS48, KBr Pellet): 1720 cm-1 (νC=O, SWNT-COOH) and 1770 cm-1 (νC=O, SWNT- COCl). [9

u d b \\xAF b \\xAF tetraquark resonances with lattice QCD potentials and the Born-Oppenheimer approximation

NASA Astrophysics Data System (ADS)

Bicudo, Pedro; Cardoso, Marco; Peters, Antje; Pflaumer, Martin; Wagner, Marc

2017-09-01

We study tetraquark resonances with lattice QCD potentials computed for a static b ¯b ¯ pair in the presence of two lighter quarks u d , the Born-Oppenheimer approximation and the emergent wave method. As a proof of concept we focus on the system with isospin I =0 , but consider different relative angular momenta l of the heavy quarks b ¯b ¯. For l =0 a bound state has already been predicted with quantum numbers I (JP)=0 (1+). Exploring various angular momenta we now compute the phase shifts and search for S and T matrix poles in the second Riemann sheet. We predict a tetraquark resonance for l =1 , decaying into two B mesons, with quantum numbers I (JP)=0 (1-) , mass m =10 57 6-4+4 MeV and decay width Γ =11 2-103+90 MeV .

A Near-Threshold Shape Resonance in the Valence-Shell Photoabsorption of Linear Alkynes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jacovella, U.; Holland, D. M. P.; Boyé-Péronne, S.

2015-12-17

The room-temperature photoabsorption spectra of a number of linear alkynes with internal triple bonds (e.g., 2-butyne, 2-pentyne, and 2- and 3-hexyne) show similar resonances just above the lowest ionization threshold of the neutral molecules. These features result in a substantial enhancement of the photoabsorption cross sections relative to the cross sections of alkynes with terminal triple bonds (e.g., propyne, 1-butyne, 1-pentyne,...). Based on earlier work on 2-butyne [Xu et al., J. Chem. Phys. 2012, 136, 154303], these features are assigned to excitation from the neutral highest occupied molecular orbital (HOMO) to a shape resonance with g (l = 4) charactermore » and approximate pi symmetry. This generic behavior results from the similarity of the HOMOs in all internal alkynes, as well as the similarity of the corresponding g pi virtual orbital in the continuum. Theoretical calculations of the absorption spectrum above the ionization threshold for the 2- and 3-alkynes show the presence of a shape resonance when the coupling between the two degenerate or nearly degenerate pi channels is included, with a dominant contribution from l = 4. These calculations thus confirm the qualitative arguments for the importance of the l = 4 continuum near threshold for internal alkynes, which should also apply to other linear internal alkynes and alkynyl radicals. The 1-alkynes do not have such high partial waves present in the shape resonance. The lower l partial waves in these systems are consistent with the broader features observed in the corresponding spectra.« less

Application of diffusion ordered-1H-nuclear magnetic resonance spectroscopy to quantify sucrose in beverages.

PubMed

Cao, Ruge; Nonaka, Airi; Komura, Fusae; Matsui, Toshiro

2015-03-15

This work focuses on a quantitative analysis of sucrose using diffusion ordered-quantitative (1)H-nuclear magnetic resonance spectroscopy (DOSY-qNMR), where an analyte can be isolated from interference based on its characteristic diffusion coefficient (D) in gradient magnetic fields. The D value of sucrose in deuterium oxide at 30°C was 4.9 × 10(-10)m(2)/s at field gradient pulse from 5.0 × 10(-2) to 3.0 × 10(-1)T/m, separated from other carbohydrates (glucose and fructose). Good linearity (r(2)=0.9999) was obtained between sucrose (0.5-20.0 g/L) and the resonance area of target glucopyranosyl-α-C1 proton normalised to that of cellobiose C1 proton (100.0 g/L, as an internal standard) in 1D sliced DOSY spectrum. The DOSY-qNMR method was successfully applied to quantify sucrose in orange juice (36.1 ± 0.5 g/L), pineapple juice (53.5 ± 1.1g/L) and a sports drink (24.7 ± 0.6g/L), in good agreement with the results obtained by an F-kit method. Copyright © 2014 Elsevier Ltd. All rights reserved.

Measurement of renal blood flow by phase-contrast magnetic resonance imaging during septic acute kidney injury: a pilot investigation.

PubMed

Prowle, John R; Molan, Maurice P; Hornsey, Emma; Bellomo, Rinaldo

2012-06-01

In septic patients, decreased renal perfusion is considered to play a major role in the pathogenesis of acute kidney injury. However, the accurate measurement of renal blood flow in such patients is problematic and invasive. We sought to overcome such obstacles by measuring renal blood flow in septic patients with acute kidney injury using cine phase-contrast magnetic resonance imaging. Pilot observational study. University-affiliated general adult intensive care unit. Ten adult patients with established septic acute kidney injury and 11 normal volunteers. Cine phase-contrast magnetic resonance imaging measurement of renal blood flow and cardiac output. The median age of the study patients was 62.5 yrs and eight were male. At the time of magnetic resonance imaging, eight patients were mechanically ventilated, nine were on continuous hemofiltration, and five required vasopressors. Cine phase-contrast magnetic resonance imaging examinations were carried out without complication. Median renal blood flow was 482 mL/min (range 335-1137) in septic acute kidney injury and 1260 mL/min (range 791-1750) in healthy controls (p = .003). Renal blood flow indexed to body surface area was 244 mL/min/m2 (range 165-662) in septic acute kidney injury and 525 mL/min/m2 (range 438-869) in controls (p = .004). In patients with septic acute kidney injury, median cardiac index was 3.5 L/min/m2 (range 1.6-8.7), and median renal fraction of cardiac output was only 7.1% (range 4.4-10.8). There was no rank correlation between renal blood flow index and creatinine clearance in patients with septic acute kidney injury (r = .26, p = .45). Cine phase-contrast magnetic resonance imaging can be used to noninvasively and safely assess renal perfusion during critical illness in man. Near-simultaneous accurate measurement of cardiac output enables organ blood flow to be assessed in the context of the global circulation. Renal blood flow seems consistently reduced as a fraction of cardiac output in established septic acute kidney injury. Cine phase-contrast magnetic resonance imaging may be a valuable tool to further investigate renal blood flow and the effects of therapies on renal blood flow in critical illness.

Decadal-scale autumn temperature reconstruction back to AD 1580 inferred from the varved sediments of Lake Silvaplana (southeastern Swiss Alps)

NASA Astrophysics Data System (ADS)

Blass, Alex; Bigler, Christian; Grosjean, Martin; Sturm, Michael

2007-09-01

A quantitative high-resolution autumn (September-November) temperature reconstruction for the southeastern Swiss Alps back to AD 1580 is presented here. We used the annually resolved biogenic silica (diatoms) flux derived from the accurately dated and annually sampled sediments of Lake Silvaplana (46°27'N, 9°48'E, 1800 m a.s.l.). The biogenic silica flux smoothed by means of a 9-yr running mean was calibrated ( r = 0.70, p < 0.01) against local instrumental temperature data (AD 1864-1949). The resulting reconstruction (± 2 standard errors = ± 0.7 °C) indicates that autumns during the late Little Ice Age were generally cooler than they were during the 20th century. During the cold anomaly around AD 1600 and during the Maunder Minimum, however, the reconstructed autumn temperatures did not experience strong negative departures from the 20th-century mean. The warmest autumns prior to 1900 occurred around AD 1770 and 1820 (0.75 °C above the 20th-century mean). Our data agree closely with two other autumn temperature reconstructions for the Alps and for Europe that are based on documentary evidence and are completely unrelated to our data, revealing a very consistent picture over the centuries.

The hydrological response of a rocky head water basin to convective rainfalls

NASA Astrophysics Data System (ADS)

Gregoretti, Carlo; Bernard, Martino; Degetto, Massimo; Matteo, Berti; Alessandro, Simoni; Stefano, Lanzoni

2015-04-01

A sharp-crested weir is installed at the outlet (altitude 1770 m a.s.l) of a rocky channel incised on the walls of Dimai Peak in the area of Fiames (Cortina d'Ampezzo, Dolomites-North Eastern Italian Alps) at the purpose of measuring runoff discharges. The area of the headwater basin is just 0.032 km2 but sub-vertical cliffs are capable to generate notable discharge during severe rainstorms. Due to the severe environment only five runoff events were measured (two times the facility was destroyed by rock falls and avalanches; other times failure of sensors stopped the measurements). Hydrological response is characterized by peaked hydrographs with very high rising limb. A kinematic distributed hydrological model was used to simulate the response of the basin to the convective rainfalls with the help of two rain gauges placed upstream the basin head and downstream the outlet respectively. The hydrological model uses an hortonian simplified law for determining excess rainfall and satisfactorily simulates the measured hydrographs. Such measurements are important for the understanding the hydrological response of a rocky basin to a convective rainfall. Their modeling are important as well when focused on predicting both flash floods in mountain torrents and the triggering conditions and magnitude of runoff generated debris flows.

Exploring on the Sensitivity Changes of the LC Resonance Magnetic Sensors Affected by Superposed Ringing Signals.

PubMed

Lin, Tingting; Zhou, Kun; Yu, Sijia; Wang, Pengfei; Wan, Ling; Zhao, Jing

2018-04-25

LC resonance magnetic sensors are widely used in low-field nuclear magnetic resonance (LF-NMR) and surface nuclear magnetic resonance (SNMR) due to their high sensitivity, low cost and simple design. In magnetically shielded rooms, LC resonance magnetic sensors can exhibit sensitivities at the fT/√Hz level in the kHz range. However, since the equivalent magnetic field noise of this type of sensor is greatly affected by the environment, weak signals are often submerged in practical applications, resulting in relatively low signal-to-noise ratios (SNRs). To determine why noise increases in unshielded environments, we analysed the noise levels of an LC resonance magnetic sensor ( L ≠ 0) and a Hall sensor ( L ≈ 0) in different environments. The experiments and simulations indicated that the superposed ringing of the LC resonance magnetic sensors led to the observed increase in white noise level caused by environmental interference. Nevertheless, ringing is an inherent characteristic of LC resonance magnetic sensors. It cannot be eliminated when environmental interference exists. In response to this problem, we proposed a method that uses matching resistors with various values to adjust the quality factor Q of the LC resonance magnetic sensor in different measurement environments to obtain the best sensitivity. The LF-NMR experiment in the laboratory showed that the SNR is improved significantly when the LC resonance magnetic sensor with the best sensitivity is selected for signal acquisition in the light of the test environment. (When the matching resistance is 10 kΩ, the SNR is 3.46 times that of 510 Ω). This study improves LC resonance magnetic sensors for nuclear magnetic resonance (NMR) detection in a variety of environments.

Tetraquark resonances computed with static lattice QCD potentials and scattering theory

NASA Astrophysics Data System (ADS)

Bicudo, Pedro; Cardoso, Marco; Peters, Antje; Pflaumer, Martin; Wagner, Marc

2018-03-01

We study tetraquark resonances with lattice QCD potentials computed for two static quarks and two dynamical quarks, the Born-Oppenheimer approximation and the emergent wave method of scattering theory. As a proof of concept we focus on systems with isospin I = 0, but consider different relative angular momenta l of the heavy b quarks. We compute the phase shifts and search for S and T matrix poles in the second Riemann sheet. We predict a new tetraquark resonance for l = 1, decaying into two B mesons, with quantum numbers I(JP) = 0(1-), mass m = 10576-4+4 MeV and decay width Γ = 112-103+90 MeV.

Breast Volume Measurement by Recycling the Data Obtained From 2 Routine Modalities, Mammography and Magnetic Resonance Imaging.

PubMed

Itsukage, Shizu; Sowa, Yoshihiro; Goto, Mariko; Taguchi, Tetsuya; Numajiri, Toshiaki

2017-01-01

Objective: Preoperative prediction of breast volume is important in the planning of breast reconstructive surgery. In this study, we prospectively estimated the accuracy of measurement of breast volume using data from 2 routine modalities, mammography and magnetic resonance imaging, by comparison with volumes of mastectomy specimens. Methods: The subjects were 22 patients (24 breasts) who were scheduled to undergo total mastectomy for breast cancer. Preoperatively, magnetic resonance imaging volume measurement was performed using a medical imaging system and the mammographic volume was calculated using a previously proposed formula. Volumes of mastectomy specimens were measured intraoperatively using a method based on Archimedes' principle and Newton's third law. Results: The average breast volumes measured on magnetic resonance imaging and mammography were 318.47 ± 199.4 mL and 325.26 ± 217.36 mL, respectively. The correlation coefficients with mastectomy specimen volumes were 0.982 for magnetic resonance imaging and 0.911 for mammography. Conclusions: Breast volume measurement using magnetic resonance imaging was highly accurate but requires data analysis software. In contrast, breast volume measurement with mammography requires only a simple formula and is sufficiently accurate, although the accuracy was lower than that obtained with magnetic resonance imaging. These results indicate that mammography could be an alternative modality for breast volume measurement as a substitute for magnetic resonance imaging.

Breast Volume Measurement by Recycling the Data Obtained From 2 Routine Modalities, Mammography and Magnetic Resonance Imaging

PubMed Central

Itsukage, Shizu; Goto, Mariko; Taguchi, Tetsuya; Numajiri, Toshiaki

2017-01-01

Objective: Preoperative prediction of breast volume is important in the planning of breast reconstructive surgery. In this study, we prospectively estimated the accuracy of measurement of breast volume using data from 2 routine modalities, mammography and magnetic resonance imaging, by comparison with volumes of mastectomy specimens. Methods: The subjects were 22 patients (24 breasts) who were scheduled to undergo total mastectomy for breast cancer. Preoperatively, magnetic resonance imaging volume measurement was performed using a medical imaging system and the mammographic volume was calculated using a previously proposed formula. Volumes of mastectomy specimens were measured intraoperatively using a method based on Archimedes’ principle and Newton's third law. Results: The average breast volumes measured on magnetic resonance imaging and mammography were 318.47 ± 199.4 mL and 325.26 ± 217.36 mL, respectively. The correlation coefficients with mastectomy specimen volumes were 0.982 for magnetic resonance imaging and 0.911 for mammography. Conclusions: Breast volume measurement using magnetic resonance imaging was highly accurate but requires data analysis software. In contrast, breast volume measurement with mammography requires only a simple formula and is sufficiently accurate, although the accuracy was lower than that obtained with magnetic resonance imaging. These results indicate that mammography could be an alternative modality for breast volume measurement as a substitute for magnetic resonance imaging. PMID:29308107

Monitoring lactic acid production during milk fermentation by in situ quantitative proton nuclear magnetic resonance spectroscopy.

PubMed

Bouteille, R; Gaudet, M; Lecanu, B; This, H

2013-04-01

When fermenting milk, lactic bacteria convert part of α- and β-lactoses into d- and l- lactic acids, causing a pH decrease responsible for casein coagulation. Lactic acid monitoring during fermentation is essential for the control of dairy gel textural and organoleptic properties, and is a way to evaluate strain efficiency. Currently, titrations are used to follow the quantity of acids formed during jellification of milk but they are not specific to lactic acid. An analytical method without the use of any reagent was investigated to quantify lactic acid during milk fermentation: in situ quantitative proton nuclear magnetic resonance spectroscopy. Two methods using in situ quantitative proton nuclear magnetic resonance spectroscopy were compared: (1) d- and l-lactic acids content determination, using the resonance of their methyl protons, showing an increase from 2.06 ± 0.02 to 8.16 ± 0.74 g/L during 240 min of fermentation; and (2) the determination of the α- and β-lactoses content, decreasing from 42.68 ± 0.02 to 30.76 ± 1.75 g/L for the same fermentation duration. The ratio between the molar concentrations of produced lactic acids and consumed lactoses enabled cross-validation, as the value (2.02 ± 0.18) is consistent with lactic acid bacteria metabolism. Copyright © 2013 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Search for dilepton resonances in pp collisions at √s=7 TeV with the ATLAS detector.

PubMed

Aad, G; Abbott, B; Abdallah, J; Abdelalim, A A; Abdesselam, A; Abdinov, O; Abi, B; Abolins, M; Abramowicz, H; Abreu, H; Acerbi, E; Acharya, B S; Adams, D L; Addy, T N; Adelman, J; Aderholz, M; Adomeit, S; Adragna, P; Adye, T; Aefsky, S; Aguilar-Saavedra, J A; Aharrouche, M; Ahlen, S P; Ahles, F; Ahmad, A; Ahsan, M; Aielli, G; Akdogan, T; Akesson, T P A; Akimoto, G; Akimov, A V; Akiyama, A; Alam, M S; Alam, M A; Albert, J; Albrand, S; Aleksa, M; Aleksandrov, I N; Alessandria, F; Alexa, C; Alexander, G; Alexandre, G; Alexopoulos, T; Alhroob, M; Aliev, M; Alimonti, G; Alison, J; Aliyev, M; Allport, P P; Allwood-Spiers, S E; Almond, J; Aloisio, A; Alon, R; Alonso, A; Alviggi, M G; Amako, K; Amaral, P; Amelung, C; Ammosov, V V; Amorim, A; Amorós, G; Amram, N; Anastopoulos, C; Ancu, L S; Andari, N; Andeen, T; Anders, C F; Anders, G; Anderson, K J; Andreazza, A; Andrei, V; Andrieux, M-L; Anduaga, X S; Angerami, A; Anghinolfi, F; Anjos, N; Annovi, A; Antonaki, A; Antonelli, M; Antonov, A; Antos, J; Anulli, F; Aoun, S; Aperio Bella, L; Apolle, R; Arabidze, G; Aracena, I; Arai, Y; Arce, A T H; Archambault, J P; Arfaoui, S; Arguin, J-F; Arik, E; Arik, M; Armbruster, A J; Arnaez, O; Arnault, C; Artamonov, A; Artoni, G; Arutinov, D; Asai, S; Asfandiyarov, R; Ask, S; Asman, B; Asquith, L; Assamagan, K; Astbury, A; Astvatsatourov, A; Atoian, G; Aubert, B; Auge, E; Augsten, K; Aurousseau, M; Austin, N; Avolio, G; Avramidou, R; Axen, D; Ay, C; Azuelos, G; Azuma, Y; Baak, M A; Baccaglioni, G; Bacci, C; Bach, A M; Bachacou, H; Bachas, K; Bachy, G; Backes, M; Backhaus, M; Badescu, E; Bagnaia, P; Bahinipati, S; Bai, Y; Bailey, D C; Bain, T; Baines, J T; Baker, O K; Baker, M D; Baker, S; Banas, E; Banerjee, P; Banerjee, Sw; Banfi, D; Bangert, A; Bansal, V; Bansil, H S; Barak, L; Baranov, S P; Barashkou, A; Barbaro Galtieri, A; Barber, T; Barberio, E L; Barberis, D; Barbero, M; Bardin, D Y; Barillari, T; Barisonzi, M; Barklow, T; Barlow, N; Barnett, B M; Barnett, R M; Baroncelli, A; Barone, G; Barr, A J; Barreiro, F; Barreiro Guimarães da Costa, J; Barrillon, P; Bartoldus, R; Barton, A E; Bartsch, D; Bartsch, V; Bates, R L; Batkova, L; Batley, J R; Battaglia, A; Battistin, M; Battistoni, G; Bauer, F; Bawa, H S; Beare, B; Beau, T; Beauchemin, P H; Beccherle, R; Bechtle, P; Beck, H P; Beckingham, M; Becks, K H; Beddall, A J; Beddall, A; Bedikian, S; Bednyakov, V A; Bee, C P; Begel, M; Behar Harpaz, S; Behera, P K; Beimforde, M; Belanger-Champagne, C; Bell, P J; Bell, W H; Bella, G; Bellagamba, L; Bellina, F; Bellomo, M; Belloni, A; Beloborodova, O; Belotskiy, K; Beltramello, O; Ben Ami, S; Benary, O; Benchekroun, D; Benchouk, C; Bendel, M; Benekos, N; Benhammou, Y; Benjamin, D P; Benoit, M; Bensinger, J R; Benslama, K; Bentvelsen, S; Berge, D; Bergeaas Kuutmann, E; Berger, N; Berghaus, F; Berglund, E; Beringer, J; Bernardet, K; Bernat, P; Bernhard, R; Bernius, C; Berry, T; Bertin, A; Bertinelli, F; Bertolucci, F; Besana, M I; Besson, N; Bethke, S; Bhimji, W; Bianchi, R M; Bianco, M; Biebel, O; Bieniek, S P; Bierwagen, K; Biesiada, J; Biglietti, M; Bilokon, H; Bindi, M; Binet, S; Bingul, A; Bini, C; Biscarat, C; Bitenc, U; Black, K M; Blair, R E; Blanchard, J-B; Blanchot, G; Blazek, T; Blocker, C; Blocki, J; Blondel, A; Blum, W; Blumenschein, U; Bobbink, G J; Bobrovnikov, V B; Bocchetta, S S; Bocci, A; Boddy, C R; Boehler, M; Boek, J; Boelaert, N; Böser, S; Bogaerts, J A; Bogdanchikov, A; Bogouch, A; Bohm, C; Boisvert, V; Bold, T; Boldea, V; Bolnet, N M; Bona, M; Bondarenko, V G; Bondioli, M; Boonekamp, M; Boorman, G; Booth, C N; Bordoni, S; Borer, C; Borisov, A; Borissov, G; Borjanovic, I; Borroni, S; Bos, K; Boscherini, D; Bosman, M; Boterenbrood, H; Botterill, D; Bouchami, J; Boudreau, J; Bouhova-Thacker, E V; Bourdarios, C; Bousson, N; Boveia, A; Boyd, J; Boyko, I R; Bozhko, N I; Bozovic-Jelisavcic, I; Bracinik, J; Braem, A; Branchini, P; Brandenburg, G W; Brandt, A; Brandt, G; Brandt, O; Bratzler, U; Brau, B; Brau, J E; Braun, H M; Brelier, B; Bremer, J; Brenner, R; 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Zolnierowski, Y; Zsenei, A; zur Nedden, M; Zutshi, V; Zwalinski, L

2011-12-30

This Letter reports on a search for narrow high-mass resonances decaying into dilepton final states. The data were recorded by the ATLAS experiment in pp collisions at √s=7  TeV at the Large Hadron Collider and correspond to a total integrated luminosity of 1.08 (1.21)  fb(-1) in the e(+)e(-) (μ(+)μ(-)) channel. No statistically significant excess above the standard model expectation is observed and upper limits are set at the 95% C.L. on the cross section times branching fraction of Z' resonances and Randall-Sundrum gravitons decaying into dileptons as a function of the resonance mass. A lower mass limit of 1.83 TeV on the sequential standard model Z' boson is set. A Randall-Sundrum graviton with coupling k/M(Pl)=0.1 is excluded at 95% C.L. for masses below 1.63 TeV.

Comparison among T1-weighted magnetic resonance imaging, modified dixon method, and magnetic resonance spectroscopy in measuring bone marrow fat.

PubMed

Shen, Wei; Gong, Xiuqun; Weiss, Jessica; Jin, Ye

2013-01-01

An increasing number of studies are utilizing different magnetic resonance (MR) methods to quantify bone marrow fat due to its potential role in osteoporosis. Our aim is to compare the measurements of bone marrow fat among T1-weighted magnetic resonance imaging (MRI), modified Dixon method (also called fat fraction MRI (FFMRI)), and magnetic resonance spectroscopy (MRS). Contiguous MRI scans were acquired in 27 Caucasian postmenopausal women with a modified Dixon method (i.e., FFMRI). Bone marrow adipose tissue (BMAT) of T1-weighted MRI and bone marrow fat fraction of the L3 vertebra and femoral necks were quantified using SliceOmatic and Matlab. MRS was also acquired at the L3 vertebra. Correlation among the three MR methods measured bone marrow fat fraction and BMAT ranges from 0.78 to 0.88 (P < 0.001) in the L3 vertebra. Correlation between BMAT measured by T1-weighted MRI and bone marrow fat fraction measured by modified FFMRI is 0.86 (P < 0.001) in femoral necks. There are good correlations among T1-weighted MRI, FFMRI, and MRS for bone marrow fat quantification. The inhomogeneous distribution of bone marrow fat, the threshold segmentation of the T1-weighted MRI, and the ambiguity of the FFMRI may partially explain the difference among the three methods.

Comparison among T1-Weighted Magnetic Resonance Imaging, Modified Dixon Method, and Magnetic Resonance Spectroscopy in Measuring Bone Marrow Fat

PubMed Central

Shen, Wei; Gong, Xiuqun; Weiss, Jessica; Jin, Ye

2013-01-01

Introduction. An increasing number of studies are utilizing different magnetic resonance (MR) methods to quantify bone marrow fat due to its potential role in osteoporosis. Our aim is to compare the measurements of bone marrow fat among T1-weighted magnetic resonance imaging (MRI), modified Dixon method (also called fat fraction MRI (FFMRI)), and magnetic resonance spectroscopy (MRS). Methods. Contiguous MRI scans were acquired in 27 Caucasian postmenopausal women with a modified Dixon method (i.e., FFMRI). Bone marrow adipose tissue (BMAT) of T1-weighted MRI and bone marrow fat fraction of the L3 vertebra and femoral necks were quantified using SliceOmatic and Matlab. MRS was also acquired at the L3 vertebra. Results. Correlation among the three MR methods measured bone marrow fat fraction and BMAT ranges from 0.78 to 0.88 (P < 0.001) in the L3 vertebra. Correlation between BMAT measured by T1-weighted MRI and bone marrow fat fraction measured by modified FFMRI is 0.86 (P < 0.001) in femoral necks. Conclusion. There are good correlations among T1-weighted MRI, FFMRI, and MRS for bone marrow fat quantification. The inhomogeneous distribution of bone marrow fat, the threshold segmentation of the T1-weighted MRI, and the ambiguity of the FFMRI may partially explain the difference among the three methods. PMID:23606951

Contour mode resonators with acoustic reflectors

DOEpatents

Olsson, Roy H [Albuquerque, NM; Fleming, James G [Albuquerque, NM; Tuck, Melanie R [Albuquerque, NM

2008-06-10

A microelectromechanical (MEM) resonator is disclosed which has a linear or ring-shaped acoustic resonator suspended above a substrate by an acoustic reflector. The acoustic resonator can be formed with a piezoelectric material (e.g. aluminum nitride, zinc oxide or PZT), or using an electrostatically-actuated material. The acoustic reflector (also termed an acoustic mirror) uses alternating sections of a relatively low acoustic impedance Z.sub.L material and a relatively high acoustic impedance Z.sub.H material to isolate the acoustic resonator from the substrate. The MEM resonator, which can be formed on a silicon substrate with conventional CMOS circuitry, has applications for forming oscillators, rf filters, and acoustic sensors.

Inter-spin distance determination using L-band (1-2 GHz) non-adiabatic rapid sweep electron paramagnetic resonance (NARS EPR)

PubMed Central

Kittell, Aaron W.; Hustedt, Eric J.; Hyde, James S.

2014-01-01

Site-directed spin-labeling electron paramagnetic resonance (SDSL EPR) provides insight into the local structure and motion of a spin probe strategically attached to a molecule. When a second spin is introduced to the system, macromolecular information can be obtained through measurement of inter-spin distances either by continuous wave (CW) or pulsed electron double resonance (ELDOR) techniques. If both methodologies are considered, inter-spin distances of 8 to 80 Å can be experimentally determined. However, there exists a region at the upper limit of the conventional X-band (9.5 GHz) CW technique and the lower limit of the four-pulse double electron-electron resonance (DEER) experiment where neither method is particularly reliable. The work presented here utilizes L-band (1.9 GHz) in combination with non-adiabatic rapid sweep (NARS) EPR to address this opportunity by increasing the upper limit of the CW technique. Because L-band linewidths are three to seven times narrower than those at X-band, dipolar broadenings that are small relative to the X-band inhomogeneous linewidth become observable, but the signal loss due to the frequency dependence of the Boltzmann factor, has made L-band especially challenging. NARS has been shown to increase sensitivity by a factor of five, and overcomes much of this loss, making L-band distance determination more feasible [1]. Two different systems are presented and distances of 18–30 Å have been experimentally determined at physiologically relevant temperatures. Measurements are in excellent agreement with a helical model and values determined by DEER. PMID:22750251

Banded Structures in Electron Pitch Angle Diffusion Coefficients from Resonant Wave Particle Interactions

NASA Technical Reports Server (NTRS)

Tripathi, A. K.; Singhal, R. P.; Khazanov, G. V.; Avanov, L. A.

2016-01-01

Electron pitch angle (D (alpha)) and momentum (D(pp)) diffusion coefficients have been calculated due to resonant interactions with electrostatic electron cyclotron harmonic (ECH) and whistler mode chorus waves. Calculations have been performed at two spatial locations L = 4.6 and 6.8 for electron energies 10 keV. Landau (n = 0) resonance and cyclotron harmonic resonances n = +/-1, +/-2,...+/-5 have been included in the calculations. It is found that diffusion coefficient versus pitch angle (alpha) profiles show large dips and oscillations or banded structures. The structures are more pronounced for ECH and lower band chorus (LBC) and particularly at location 4.6. Calculations of diffusion coefficients have also been performed for individual resonances. It is noticed that the main contribution of ECH waves in pitch angle diffusion coefficient is due to resonances n = +1 and n = +2. A major contribution to momentum diffusion coefficients appears from n = +2. However, the banded structures in D alpha and Dpp coefficients appear only in the profile of diffusion coefficients for n = +2. The contribution of other resonances to diffusion coefficients is found to be, in general, quite small or even negligible. For LBC and upper band chorus waves, the banded structures appear only in Landau resonance. The Dpp diffusion coefficient for ECH waves is one to two orders smaller than D alpha coefficients. For chorus waves, Dpp coefficients are about an order of magnitude smaller than D alpha coefficients for the case n does not = 0. In case of Landau resonance, the values of Dpp coefficient are generally larger than the values of D alpha coefficients particularly at lower energies. As an aid to the interpretation of results, we have also determined the resonant frequencies. For ECH waves, resonant frequencies have been estimated for wave normal angle 89 deg and harmonic resonances n = +1, +2, and +3, whereas for whistler mode waves, the frequencies have been calculated for angle 10 deg and Landau resonance. Further, in ECH waves, the banded structures appear for electron energies (is) greater than1 keV, and for whistler mode chorus waves, structures appear for energies greater than 2 keV at L = 4.6 and above 200 eV for L = 6.8. The results obtained in the present work will be helpful in the study of diffusion curves and will have important consequences for diffuse aurora and pancake distributions.

Banded Structures in Electron Pitch Angle Diffusion Coefficients from Resonant Wave-Particle Interactions

NASA Technical Reports Server (NTRS)

Tripathi, A. K.; Singhal, R. P.; Khazanov, G. V.; Avanov, L. A.

2016-01-01

Electron pitch angle (D(sub (alpha alpha))) and momentum (D(sub pp)) diffusion coefficients have been calculated due to resonant interactions with electrostatic electron cyclotron harmonic (ECH) and whistler mode chorus waves. Calculations have been performed at two spatial locations L=4.6 and 6.8 for electron energies less than or equal to 10 keV. Landau (n=0) resonance and cyclotron harmonic resonances n= +/- 1, +/-2, ... +/-5 have been included in the calculations. It is found that diffusion coefficient versus pitch angle (alpha) profiles show large dips and oscillations or banded structures. The structures are more pronounced for ECH and lower band chorus (LBC) and particularly at location 4.6. Calculations of diffusion coefficients have also been performed for individual resonances. It is noticed that the main contribution of ECH waves in pitch angle diffusion coefficient is due to resonances n=+1 and n=+2. A major contribution to momentum diffusion coefficients appears from n=+2. However, the banded structures in D(sub alpha alpha) and D(sub pp) coefficients appear only in the profile of diffusion coefficients for n=+2. The contribution of other resonances to diffusion coefficients is found to be, in general, quite small or even negligible. For LBC and upper band chorus waves, the banded structures appear only in Landau resonance. The D(sub pp) diffusion coefficient for ECH waves is one to two orders smaller than D(sub alpha alpha) coefficients. For chorus waves, D(sub pp) coefficients are about an order of magnitude smaller than D(sub alpha alpha) coefficients for the case n does not equal 0. In case of Landau resonance, the values of D(sub pp) coefficient are generally larger than the values of D(sub alpha alpha) coefficients particularly at lower energies. As an aid to the interpretation of results, we have also determined the resonant frequencies. For ECH waves, resonant frequencies have been estimated for wave normal angle 89 deg and harmonic resonances n= +1, +2, and +3, whereas for whistler mode waves, the frequencies have been calculated for angle 10 deg and Landau resonance. Further, in ECH waves, the banded structures appear for electron energies 1 greater than or equal to keV, and for whistler mode chorus waves, structures appear for energies greater than 2 keV at L=4.6 and above 200 eV for L=6.8. The results obtained in the present work will be helpful in the study of diffusion curves and will have important consequences for diffuse aurora and pancake distributions.

Spherical and cylindrical particle resonator as a cloak system

NASA Astrophysics Data System (ADS)

Minin, I. V.; Minin, O. V.; Eremeev, A. I.; Tseplyaev, I. S.

2018-05-01

The concept of dielectric spherical or cylindrical particle in resonant mode as a cloak system is offered. In fundamental modes (modes with the smallest volume correspond to |m| = l, and s = 1) the field is concentrated mostly in the equatorial plane and at the surface of the sphere. Thus under resonance modes, such perturbation due to cuboid particle inserted in the spherical or cylindrical particle has almost no effect on the field forming resonance regardless of the value of internal particle material (defect) as long as this material does not cover the region where resonance takes place.

Numerical Investigation of Transition in Supersonic Boundary Layers Using DNS and LES

DTIC Science & Technology

2008-03-31

stream values of velocity, temperature, density, and specific heat ( Uro , Tio, Pe and C2, respectively). For investigations of flows over cones, free...field is simulated without those assumptions for the current investigations. For 2,5 2 UI.l UL u* lO Pn 2BL - - Tl" TU o DNS ’. DNS PDNS T DNS T DNS 025...Because primary amplitude levels impact the resonance behavior, the resonance lo - cation moved upstream to R., = 1, 800 and the nonlinear amplification

Distribution and absorption of local anesthetics in inferior alveolar nerve block: evaluation by magnetic resonance imaging.

PubMed

Ay, Sinan; Küçük, Dervisşhan; Gümüş, Cesur; Kara, M Isa

2011-11-01

The aim of this study was to evaluate the distribution and absorption of local anesthetic solutions in inferior alveolar nerve block using magnetic resonance imaging. Forty healthy volunteers were divided into 4 groups and injected with 1.5 mL for inferior alveolar nerve block and 0.3 mL for lingual nerve block. The solutions used for the different groups were 2% lidocaine, 2% lidocaine with 0.125 mg/mL epinephrine, 4% articaine with 0.006 mg/mL epinephrine, and 4% articaine with 0.012 mg/mL epinephrine. All subjects had axial T2-weighted and fat-suppressed images at 0, 60, and 120 minutes after injection. The localization, area, and intensity (signal characteristics) of the solutions were analyzed and onset and duration times of the anesthesia were recorded. There were no significant differences between groups with regard to the intensity and area of the solutions at 0, 60, and 120 minutes after injection, but differences were found within each group. No between-group differences were found on magnetic resonance imaging in the distribution and absorption of lidocaine with or without epinephrine and articaine with 0.006 and 0.012 mg/mL epinephrine. All solutions were noticeably absorbed at 120 minutes after injection. Copyright © 2011 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

News on the Scissors Mode

NASA Astrophysics Data System (ADS)

Pietralla, N.; Beller, J.; Beck, T.; Derya, V.; Löher, B.; Romig, C.; Savran, D.; Scheck, M.; Tornow, W.; Zweidinger, M.

2014-09-01

We report on our recent nuclear resonance fluorescence experiments on l52,l54,l56Gd. Decay branches of the scissors mode to intrinsic excitations are observed. They are interpreted as a new signature for a spherical-to-deformed nuclear shape phase transition.

A few words about resonances in the electroweak effective Lagrangian

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rosell, Ignasi; Pich, Antonio; Santos, Joaquín

Contrary to a widely spread believe, we have demonstrated that strongly coupled electroweak models including both a light Higgs-like boson and massive spin-1 resonances are not in conflict with experimental constraints on the oblique S and T parameters. We use an effective Lagrangian implementing the chiral symmetry breaking SU (2){sub L} ⊗ SU (2){sub R} → SU (2){sub L+R} that contains the Standard Model gauge bosons coupled to the electroweak Goldstones, one Higgs-like scalar state h with mass m{sub h} = 126 GeV and the lightest vector and axial-vector resonance multiplets V and A. We have considered the one-loop calculationmore » of S and T in order to study the viability of these strongly-coupled scenarios, being short-distance constraints and dispersive relations the main ingredients of the calculation. Once we have constrained the resonance parameters, we do a first approach to the determination of the low energy constants of the electroweak effective theory at low energies (without resonances). We show this determination in the case of the purely Higgsless bosonic Lagrangian.« less

Analysis of antimycin A by reversed-phase liquid chromatography/nuclear magnetic-resonance spectrometry

USGS Publications Warehouse

Ha, Steven T.K.; Wilkins, Charles L.; Abidi, Sharon L.

1989-01-01

A mixture of closely related streptomyces fermentation products, antimycin A, Is separated, and the components are identified by using reversed-phase high-performance liquid chromatography with directly linked 400-MHz proton nuclear magnetic resonance detection. Analyses of mixtures of three amino acids, alanine, glycine, and valine, are used to determine optimal measurement conditions. Sensitivity increases of as much as a factor of 3 are achieved, at the expense of some loss in chromatographic resolution, by use of an 80-μL NMR cell, Instead of a smaller 14-μL cell. Analysis of the antimycin A mixture, using the optimal analytical high performance liquid chromatography/nuclear magnetic resonance conditions, reveals it to consist of at least 10 closely related components.

Magnetic resonance imaging-directed transperineal limited-mapping prostatic biopsies to diagnose prostate cancer: a Scottish experience.

PubMed

Mukherjee, Ankur; Morton, Simon; Fraser, Sioban; Salmond, Jonathan; Baxter, Grant; Leung, Hing Y

2014-11-01

Transperineal prostatic biopsy is firmly established as an important tool in the diagnosis of prostate cancer. The benefit of additional imaging (magnetic resonance imaging) to target biopsy remains to be fully addressed. Using a cohort of consecutive patients undergoing transperineal template mapping biopsies, we studied positive biopsies in the context of magnetic resonance imaging findings and examined the accuracy of magnetic resonance imaging in predicting the location of transperineal template mapping biopsies-detected prostate cancer. Forty-four patients (mean age: 65 years, range 53-78) underwent transperineal template mapping biopsies. Thirty-four patients had 1-2 and 10 patients had ≥3 previous transrectal ultrasound scan-guided biopsies. The mean prostate-specific antigen was 15 ng/mL (range 2.5-79 ng/mL). High-grade prostatic intraepithelial neoplasia was found in 12 (27%) patients and prostate cancer with Gleason <7, 7 and >7 in 13, 10 and 8 patients, respectively. Suspicious lesions on magnetic resonance imaging scans were scored from 1 to 5. In 28 patients, magnetic resonance imaging detected lesions with score ≥3. Magnetic resonance imaging correctly localised transperineal template mapping biopsies-detected prostate cancer in a hemi-gland approach, particularly in a right to left manner (79% positive prediction rate), but not in a quadrant approach (33% positive prediction rate). Our findings support the notion of magnetic resonance imaging-based selection of patients for transperineal template mapping biopsies and that lesions revealed by magnetic resonance imaging are likely useful for targeted biopsies. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

Photoionization pathways and thresholds in generation of Lyman-α radiation by resonant four-wave mixing in Kr-Ar mixture

NASA Astrophysics Data System (ADS)

Louchev, Oleg A.; Saito, Norihito; Oishi, Yu; Miyazaki, Koji; Okamura, Kotaro; Nakamura, Jumpei; Iwasaki, Masahiko; Wada, Satoshi

2016-09-01

We develop a set of analytical approximations for the estimation of the combined effect of various photoionization processes involved in the resonant four-wave mixing generation of ns pulsed Lyman-α (L-α ) radiation by using 212.556 nm and 820-845 nm laser radiation pulses in Kr-Ar mixture: (i) multi-photon ionization, (ii) step-wise (2+1)-photon ionization via the resonant 2-photon excitation of Kr followed by 1-photon ionization and (iii) laser-induced avalanche ionization produced by generated free electrons. Developed expressions validated by order of magnitude estimations and available experimental data allow us to identify the area for the operation under high input laser intensities avoiding the onset of full-scale discharge, loss of efficiency and inhibition of generated L-α radiation. Calculations made reveal an opportunity for scaling up the output energy of the experimentally generated pulsed L-α radiation without significant enhancement of photoionization.

Morphogenetic Effects of Resettlement of Mole Voles (Ellobius talpinus Pall., 1770) from the Southern Population to the Northern Boundary of the Species Range.

PubMed

Vasil'ev, A G; Bol'shakov, V N; Vasil'eva, I A; Evdokimov, N G; Sineva, N V

2018-01-01

Geometric morphometry has been used to reveal transformations of mandible morphogenesis in the offspring of mole voles resettled to the northern part of the species range from a southern population. The transformations were new compared to both the original (southern) and the aboriginal (northern) populations. A significant increase in the intragroup morphological disparity estimated by the mean nearest neighbor distance (MNND) in the resettled animals compared to both aboriginal populations is an indirect indication of an increased developmental instability in the resettled animals exposed to new climatic conditions.

KSC-04pd1770

NASA Image and Video Library

2004-09-10

KENNEDY SPACE CENTER, FLA. - Members of a hurricane assessment team from Johnson Space Center and Marshall Space Flight Center tour the Thermal Protection System (TPS) Facility at KSC after Hurricane Frances hit the east coast of Central Florida and Kennedy Space Center. At left is Martin Wilson, manager of the TPS operations. The facility, which creates the TPS tiles, blankets and all the internal thermal control systems for the Space Shuttles, is almost totally unserviceable at this time after losing approximately 35 percent of its roof. Equipment and materials that survived the storm have been relocated to the RLV hangar near the KSC Shuttle Landing Facility.

A 500-year seasonally resolved δ18O and δ13C, layer thickness and calcite aspect record from a speleothem deposited in the Han-sur-Lesse cave, Belgium

NASA Astrophysics Data System (ADS)

Van Rampelbergh, M.; Verheyden, S.; Allan, M.; Quinif, Y.; Cheng, H.; Edwards, L. R.; Keppens, E.; Claeys, P.

2015-06-01

Speleothem δ18O and δ13C signals enable climate reconstructions at high resolution. However, scarce decadal and seasonally resolved speleothem records are often difficult to interpret in terms of climate due to the multitude of factors that affect the proxy signals. In this paper, a fast-growing (up to 2 mm yr-1) seasonally laminated speleothem from the Han-sur-Lesse cave (Belgium) is analyzed for its δ18O and δ13C values, layer thickness and changes in calcite aspect. The studied record covers the period between AD 2001 and 1479 as indicated by layer counting and confirmed by 20 U / Th ages. The Proserpine proxies are seasonally biased and document drier (and colder) winters on multidecadal scales. Higher δ13C signals reflect increased prior calcite precipitation (PCP) and lower soil activity during drier (and colder) winters. Thinner layers and darker calcite relate to slower growth and exist during drier (and colder) winter periods. Exceptionally dry (and cold) winter periods occur from 1565 to 1610, at 1730, from 1770 to 1800, from 1810 to 1860, and from 1880 to 1895 and correspond to exceptionally cold periods in historical and instrumental records as well as European winter temperature reconstructions. More relative climate variations, during which the four measured proxies vary independently and display lower amplitude variations, occur between 1479 and 1565, between 1610 and 1730, and between 1730 and 1770. The winters during the first and last periods are interpreted as relatively wetter (and warmer) and correspond to warmer periods in historical data and in winter temperature reconstructions in Europe. The winters in the period between 1610 and 1730 are interpreted as relatively drier (and cooler) and correspond to generally colder conditions in Europe. Interpretation of the seasonal variations in δ18O and δ13C signals differs from that on a decadal and multidecadal scale. Seasonal δ18O variations reflect cave air temperature variations and suggest a 2.5 °C seasonality in cave air temperature during the two relatively wetter (and warmer) winter periods (1479-1565 and 1730-1770), which corresponds to the cave air temperature seasonality observed today. Between 1610 and 1730, the δ18O values suggest a 1.5 °C seasonality in cave air temperature, indicating colder summer temperatures during this drier (and cooler) interval. The δ13C seasonality is driven by PCP and suggests generally lower PCP seasonal effects between 1479 and 1810 compared to today. A short interval of increased PCP seasonality occurs between 1600 and 1660, and reflects increased PCP in summer due to decreased winter recharge.

Lumbar Gout Tophus Mimicking Epidural Abscess with Magnetic Resonance Imaging, Bone, and Gallium Scans

PubMed Central

Vicente, Justo Serrano; Gómez, Alejandro Lorente; Moreno, Rafael Lorente; Torre, Jose Rafael Infante; Bernardo, Lucía García; Madrid, Juan Ignacio Rayo

2018-01-01

Gout is a common metabolic disorder, typically diagnosed in peripheral joints. Tophaceous deposits in lumbar spine are a very rare condition with very few cases reported in literature. The following is a case report of a 52-year-old patient with low back pain, left leg pain, and numbness. Serum uric acid level was in normal range. magnetic resonance imaging, bone scan, and gallium-67 images suggested an inflammatory-infectious process focus at L4. After a decompressive laminectomy at L4–L5 level, histological examination showed a chalky material with extensive deposition of amorphous gouty material surrounded by macrophages and foreign-body giant cells (tophaceous deposits). PMID:29643682

Lumbar Gout Tophus Mimicking Epidural Abscess with Magnetic Resonance Imaging, Bone, and Gallium Scans.

PubMed

Vicente, Justo Serrano; Gómez, Alejandro Lorente; Moreno, Rafael Lorente; Torre, Jose Rafael Infante; Bernardo, Lucía García; Madrid, Juan Ignacio Rayo

2018-01-01

Gout is a common metabolic disorder, typically diagnosed in peripheral joints. Tophaceous deposits in lumbar spine are a very rare condition with very few cases reported in literature. The following is a case report of a 52-year-old patient with low back pain, left leg pain, and numbness. Serum uric acid level was in normal range. magnetic resonance imaging, bone scan, and gallium-67 images suggested an inflammatory-infectious process focus at L4. After a decompressive laminectomy at L4-L5 level, histological examination showed a chalky material with extensive deposition of amorphous gouty material surrounded by macrophages and foreign-body giant cells (tophaceous deposits).

Hearing the transformation of conical to closed-pipe resonances

NASA Astrophysics Data System (ADS)

Ruiz, Michael J.

2017-05-01

The harmonics for an open cone with slant length L are the same as the harmonics for an open pipe with length L . When the cone is transformed through phases of closed-open conical frusta into a cylinder of length L closed at one end, the fundamental halves and only odd harmonics remain. A simple approach using boundary conditions is presented in order to understand this remarkable fact. A new free interactive HMTL5 application is provided which enables the user to hear the resonances of a complete cone transform into the pitches of a conical frustum closed at the small end, and eventually into the odd harmonics of a closed cylindrical pipe.

Detection of ochratoxin A (OTA) in coffee using chemiluminescence resonance energy transfer (CRET) aptasensor.

PubMed

Jo, Eun-Jung; Mun, Hyoyoung; Kim, Su-Ji; Shim, Won-Bo; Kim, Min-Gon

2016-03-01

We report a chemiluminescence resonance energy transfer (CRET) aptasensor for the detection of ochratoxin A (OTA) in roasted coffee beans. The aptamer sequences used in this study are 5'-DNAzyme-Linker-OTA aptamer-3'-dabcyl. Dabcyl at the end of the OTA aptamer region plays as a quencher in CRET aptasensor. When hemin and OTA are added, the dabcyl-labeled OTA aptamer approaches to the G-quadruplex-hemin complex by formation of the G-quadruplex-OTA complex. The G-quadruplex-hemin complexes possess horseradish peroxidase (HRP)-like activity, and therefore, the HRP-mimicking DNAzyme (HRPzyme) catalyzes peroxidation in the presence of luminol and H2O2. Resonance energy transfer between luminol (donor) and dabcyl (acceptor) enables quenching of chemiluminescence signals. The signal decreases with increasing the concentration of OTA within the range of 0.1-100ngmL(-1) (limit of detection 0.22ngmL(-1)), and the level of recovery of the respective 1ngmL(-1) and 10ngmL(-1) spiked coffee samples was 71.5% and 93.3%. These results demonstrated the potential of the proposed method for OTA analysis in diverse foods. Copyright © 2015 Elsevier Ltd. All rights reserved.

Determination of Trace lead (II) by Resonance Light Scattering Based on Pb (II)-KI-MG System

NASA Astrophysics Data System (ADS)

Chen, Ninghua; Yang, Yingchun; Hao, Shuai; Li, Yangmin

2018-01-01

In pH=3.0 weak acidic solution, it is found that Pb2+ can react with I-to form [PbI4]2-, and it further reacted with MG to form ion-association complex. As a result, the new spectra of RLS appeared and their intensities enhanced greatly. Accordingly, a new method developed for the determination of Pb (II).The appropriate reaction conditions were optimized through experiments. The results show that a strong and stable resonance scattering spectra emerge at the wavelength of 338 nm. The resonance light scattering strength (ΔIRLS) has good linear relationship with the concentration of Pb (II) in the range of 0.2 μg/mL ~ 1.0 μg/mL. The detection limits (LOD) is 0.0155 μg/mL. The relative standard deviation (RSD) is 3.61% (n=11) for the determination of 0.6 μg/mL Pb (II) standard solution. And this method was successfully applied to the determination of three environmental water samples (nongfu spring, tap water, laboratory wastewater). Results illustrate that the addition standard recovery are 80%~107% with relative standard deviation (RSD) between 1.8% to 4.6%.

Intestinal fluid volumes and transit of dosage forms as assessed by magnetic resonance imaging.

PubMed

Schiller, C; Fröhlich, C-P; Giessmann, T; Siegmund, W; Mönnikes, H; Hosten, N; Weitschies, W

2005-11-15

The gastrointestinal transit of sequentially administered capsules was investigated in relation to the availability of fluid along the intestinal lumen by magnetic resonance imaging. Water-sensitive magnetic resonance imaging was performed on 12 healthy subjects during fasting and 1 h after a meal. Specifiable non-disintegrating capsules were administered at 7, 4 and 1 h prior to imaging. While food intake reduced the mean fluid volumes in the small intestine (105 +/- 72 mL vs. 54 +/- 41 mL, P < 0.01) it had no significant effect on the mean fluid volumes in the colon (13 +/- 12 mL vs. 18 +/- 26 mL). The mean number of separated fluid pockets increased in both organs after meal (small intestine: 4 vs. 6, P < 0.05; large intestine: 4 vs. 6, P < 0.05). The distribution of capsules between the small and large intestine was strongly influenced by food (colon: 3 vs. 17 capsules, P < 0.01). The results show that fluid is not homogeneously distributed along the gut, which likely contributes to the individual variability of drug absorption. Furthermore, transport of fluid and solids through the ileocaecal valve is obviously initiated by a meal-induced gastro-ileocaecal reflex.

Tidal interactions of a Maclaurin spheroid - II. Resonant excitation of modes by a close, misaligned orbit

NASA Astrophysics Data System (ADS)

Braviner, Harry J.; Ogilvie, Gordon I.

2015-02-01

We model a tidally forced star or giant planet as a Maclaurin spheroid, decomposing the motion into the normal modes found by Bryan. We first describe the general prescription for this decomposition and the computation of the tidal power. Although this formalism is very general, forcing due to a companion on a misaligned, circular orbit is used to illustrate the theory. The tidal power is plotted for a variety of orbital radii, misalignment angles, and spheroid rotation rates. Our calculations are carried out including all modes of degree l ≤ 4, and the same degree of gravitational forcing. Remarkably, we find that for close orbits (a/R* ≈ 3) and rotational deformations that are typical of giant planets (e ≈ 0.4) the l = 4 component of the gravitational potential may significantly enhance the dissipation through resonance with surface gravity modes. There are also a large number of resonances with inertial modes, with the tidal power being locally enhanced by up to three orders of magnitude. For very close orbits (a/R* ≈ 3), the contribution to the power from the l = 4 modes is roughly the same magnitude as that due to the l = 3 modes.

Lanthanide binding and IgG affinity construct: Potential applications in solution NMR, MRI, and luminescence microscopy

PubMed Central

Barb, Adam W; Ho, Tienhuei Grace; Flanagan-Steet, Heather; Prestegard, James H

2012-01-01

Paramagnetic lanthanide ions when bound to proteins offer great potential for structural investigations that utilize solution nuclear magnetic resonance spectroscopy, magnetic resonance imaging, or optical microscopy. However, many proteins do not have native metal ion binding sites and engineering a chimeric protein to bind an ion while retaining affinity for a protein of interest represents a significant challenge. Here we report the characterization of an immunoglobulin G-binding protein redesigned to include a lanthanide binding motif in place of a loop between two helices (Z-L2LBT). It was shown to bind Tb3+ with 130 nM affinity. Ions such as Dy3+, Yb3+, and Ce3+ produce paramagnetic effects on NMR spectra and the utility of these effects is illustrated by their use in determining a structural model of the metal-complexed Z-L2LBT protein and a preliminary characterization of the dynamic distribution of IgG Fc glycan positions. Furthermore, this designed protein is demonstrated to be a novel IgG-binding reagent for magnetic resonance imaging (Z-L2LBT:Gd3+ complex) and luminescence microscopy (Z-L2LBT: Tb3+ complex). PMID:22851279

Validity and reliability of the Short Form 36 Health Surveys (SF-36) among patients with spondyloarthritis in Singapore.

PubMed

Kwan, Yu Heng; Fong, Warren Weng Seng; Lui, Nai Lee; Yong, Si Ting; Cheung, Yin Bun; Malhotra, Rahul; Østbye, Truls; Thumboo, Julian

2016-12-01

The Short Form 36 Health Survey (SF-36) is a popular health-related quality of life (HrQoL) tool. However, few studies have assessed its psychometric properties in patients with spondyloarthritis (SpA). We therefore aimed to assess the reliability and validity of the SF-36 in patients with SpA in Singapore. Cross-sectional data from a registry of 196 SpA patients recruited from a dedicated tertiary referral clinic in Singapore from 2011 to 2014 was used. Analyses were guided by the COnsensus-based Standards for the selection of health Measurement INstruments framework. Internal consistency reliability was assessed using Cronbach's alpha. Construct validity was assessed through 33 a priori hypotheses by correlations of the eight subscales and two summary scores of SF-36 with other health outcomes. Known-group construct validity was assessed by comparison of the means of the subscales and summary scores of the SF-36 of SpA patients and the general population of Singapore using student's t tests. Among 196 patients (155 males (79.0 %), median (range) age: 36 (17-70), 166 Chinese (84.6 %)), SF-36 scales showed high internal consistency ranging from 0.88 to 0.90. Convergent construct validity was supported as shown by fulfillment of all hypotheses. Divergent construct validity was supported, as SF-36 MCS was not associated with PGA, pain and HAQ. Known-group construct validity showed SpA patients had lower scores of 3.8-12.5 when compared to the general population at p < 0.001. This study supports the SF-36 as a valid and reliable measure of HrQoL for use in patients with SpA at a single time point.

Short-term effect of short, intensive speech therapy on articulation and resonance in Ugandan patients with cleft (lip and) palate.

PubMed

Luyten, A; Bettens, K; D'haeseleer, E; Hodges, A; Galiwango, G; Vermeersch, H; Van Lierde, K

2016-01-01

The purpose of the current study was to assess the short-term effectiveness of short and intensive speech therapy provided to patients with cleft (lip and) palate (C(L)P) in terms of articulation and resonance. Five Ugandan patients (age: 7.3-19.6 years) with non-syndromic C(L)P received six hours of individualized speech therapy in three to four days. Speech therapy focused on correct phonetic placement and contrasts between oral and nasal airflow and resonance. Speech evaluations performed before and immediately after speech therapy, including perceptual and instrumental assessment techniques, were compared. Post-therapy, improvement of speech was noted for most of the patients, although to varying degrees. Clinically relevant progress of objective nasalance values and/or articulation was obtained in four patients. Overall, two patients showed normal speech intelligibility, while three patients required additional speech therapy. These preliminary short-term results demonstrate that short and intensive speech therapy can be effective for patients with C(L)P in countries with limited access to speech-language therapy. However, further research is needed on the long-term effectiveness and the advantages of applying this treatment protocol in countries with good access to speech therapy. The reader will be able to (1) list the challenges in resource poor-countries to achieve access to speech-language therapy services, (2) describe when the application of speech therapy is appropriate in patients with C(L)P, (3) describe the speech therapy that can be applied to reduce compensatory articulation and resonance disorders in patients with C(L)P, and (4) list the (possible) advantages of short, intensive speech therapy for both resource-poor and developed countries. Copyright © 2016 Elsevier Inc. All rights reserved.

Resonances in low-energy positron-alkali scattering

NASA Technical Reports Server (NTRS)

Horbatsch, M.; Ward, S. J.; Mceachran, R. P.; Stauffer, A. D.

1990-01-01

Close-coupling calculations were performed with up to five target states at energies in the excitation threshold region for positron scattering from Li, Na and K. Resonances were discovered in the L = 0, 1 and 2 channels in the vicinity of the atomic excitation thresholds. The widths of these resonances vary between 0.2 and 130 MeV. Evidence was found for the existence of positron-alkali bound states in all cases.

Magnetic resonance imaging in the assessment of anomalous pulmonary venous connections.

PubMed

Bernal Garnes, N; Méndez Díaz, C; Soler Fernández, R; Rodríguez García, E

2016-01-01

To illustrate the morphological and functional magnetic resonance findings for total and partial anomalous pulmonary venous connections as well as of the most common complications after surgery. The magnetic resonance findings are fundamental in defining the type of anomalous connection, deciding on the treatment, planning the surgery, and detecting postsurgical complications. Copyright © 2015 SERAM. Published by Elsevier España, S.L.U. All rights reserved.

Muscle Injury After Intramuscular Administration of Diclofenac: A Case Report Supported by Magnetic Resonance Imaging.

PubMed

Probst, Mareike; Kühn, Jens-Peter; Modeß, Christiane; Scheuch, Eberhard; Seidlitz, Anne; Hosten, Norbert; Siegmund, Werner; Weitschies, Werner

2017-12-01

Intramuscular injection of diclofenac is still frequently practiced, although there is ample evidence that the risk of local tissue intolerability is highly underestimated. The aim of this study was to evaluate local toxicity in a patient using magnetic resonance imaging. A patient who gave written informed consent received a medically indicated intramuscular administration of diclofenac 75 mg/2 mL. Simultaneously with magnetic resonance imaging of the depot, a clinical-chemical evaluation and quantification of diclofenac in plasma was performed. A manifold enhancement of the T2-weighted magnetic resonance signal was observed in a muscle area of approximately 60 mL volume, with maximum signal intensity 30 min after injection, the time of maximum diclofenac plasma exposure. Plasma creatine kinase activity was elevated approximately sixfold within 8 h and normalized within 1 week, whereas the magnetic resonance enhancement disappeared within 5 weeks. Interestingly, the patient did not complain about any clinical symptoms at the injection site. Asymptomatic tissue injury after intramuscular injection of diclofenac, caused by intramuscular dosing, can be reliably evaluated by magnetic resonance imaging and should be applied early during the development of parenteral dosage forms. Clinical Trials Registration Number: BB130/16 (Ethics Committee of the University Medicine Greifswald).

Determination of nucleic acids based on the quenching effect on resonance light scattering of the Y(III)-1,6-bi(1'-phenyl-3'-methyl-5'-pyrazolone-4'-)hexane-dione system.

PubMed

Wu, Xia; Yang, Jing He; Sun, Shuna; Guo, Changying; Ran, Dehuan; Zheng, Jinhua

2006-01-01

Nucleic acids can quench resonance light scattering (RLS) intensity of the Y(III)-1,6-bi(1'-phenyl-3'-methyl-5'-pyrazolone-4'-)hexane-dione(BPMPHD) complex in the pH range 5.0-5.8. Under optimal conditions, there are linear relationships between the quenching of RLS and the concentration of nucleic acids in the range 6.3 x 10(-8)-2.1 x 10(-5) g/mL for fish sperm DNA (fsDNA), 1.2 x 10(-8)-5.0 x 10(-5) g/mL for calf thymus DNA (ctDNA) and 6.0 x 10(-8)-2.0 x 10(-5) g/mL for yeast RNA (yRNA). The detection limits (3 s) of fsDNA, ctDNA and yRNA are 0.7 ng/mL, 3.8 ng/mL and 4.2 ng/mL, respectively. Copyright (c) 2006 John Wiley & Sons, Ltd.

Atomic layer MoS2-graphene van der Waals heterostructure nanomechanical resonators.

PubMed

Ye, Fan; Lee, Jaesung; Feng, Philip X-L

2017-11-30

Heterostructures play significant roles in modern semiconductor devices and micro/nanosystems in a plethora of applications in electronics, optoelectronics, and transducers. While state-of-the-art heterostructures often involve stacks of crystalline epi-layers each down to a few nanometers thick, the intriguing limit would be hetero-atomic-layer structures. Here we report the first experimental demonstration of freestanding van der Waals heterostructures and their functional nanomechanical devices. By stacking single-layer (1L) MoS 2 on top of suspended single-, bi-, tri- and four-layer (1L to 4L) graphene sheets, we realize an array of MoS 2 -graphene heterostructures with varying thickness and size. These heterostructures all exhibit robust nanomechanical resonances in the very high frequency (VHF) band (up to ∼100 MHz). We observe that fundamental-mode resonance frequencies of the heterostructure devices fall between the values of graphene and MoS 2 devices. Quality (Q) factors of heterostructure resonators are lower than those of graphene but comparable to those of MoS 2 devices, suggesting interface damping related to interlayer interactions in the van der Waals heterostructures. This study validates suspended atomic layer heterostructures as an effective device platform and provides opportunities for exploiting mechanically coupled effects and interlayer interactions in such devices.

Search for Dilepton Resonances in pp Collisions at √s=7 TeV with the ATLAS Detector

DOE PAGES

Aad, G.; Abbott, B.; Abdallah, J.; ...

2011-12-29

This Letter reports on a search for narrow high-mass resonances decaying into dilepton final states. The data were recorded by the ATLAS experiment in pp collisions at √s=7 TeV at the Large Hadron Collider and correspond to a total integrated luminosity of 1.08 (1.21) fb⁻¹ in the e⁺e⁻ (μ⁺μ⁻) channel. No statistically significant excess above the standard model expectation is observed and upper limits are set at the 95% C.L. on the cross section times branching fraction of Z' resonances and Randall-Sundrum gravitons decaying into dileptons as a function of the resonance mass. A lower mass limit of 1.83 TeVmore » on the sequential standard model Z' boson is set. A Randall-Sundrum graviton with coupling k/M¯¯¯¯ Pl=0.1 is excluded at 95% C.L. for masses below 1.63 TeV.« less

Direct monitoring by carbon-13 nuclear magnetic resonance spectroscopy of the metabolism and metabolic rate of 13C-labeled compounds in vivo.

PubMed

Iida, K; Hidoh, O; Fukami, J; Kajiwara, M

1991-01-01

Carbon-13 nuclear magnetic resonance spectroscopy has been used to observe the transformations of [1-13C]-D-glucose to [1,1'-13C2]-D-trehalose, and [3-13C]-L-alanine to [2-13C]-L-glutamic acid in the living body of Gryllodes sigillatus. [3-13C]-D-Alanine was not metabolized. The metabolic rate of [1-13C]-D-glucose was found to be altered by prior injection of boric acid.

Direct Detection of Time-Resolved Rabi Oscillationsin a Single Quantum Dot via Resonance Fluorescence

DTIC Science & Technology

2013-03-19

Ware, E. A. Stinaff, D. Gammon, M. F. Doty, A. S . Bracker, D. Gershoni, V. L. Korenev , S . C. Bădescu, Y. Lyanda-Geller, and T. L. Reinecke, Phys. Rev...A SINGLE QUANTUM DOT VIA RESONANCE FLUORESCENCE 5a. CONTRACT NUMBER FA8750-12-2-0333 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) J...NUMBER CH 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) University of Michigan 450 Church Street Ann Arbor MI 48109-1040 8. PERFORMING

Nanocell with a pressure-controlled Rb atomic vapor column thickness: Critical influence of the thickness on optical processes

NASA Astrophysics Data System (ADS)

Sargsyan, A.; Amiryan, A.; Cartaleva, S.; Sarkisyan, D.

2017-07-01

A new device is designed: it consists of a nanocell (NC) filled with Rb atom vapors and placed in a vacuum chamber. When the pressure in the chamber changes in the range 0-1 atm, the NC thickness is smoothly varied in the range L = 140-1700 nm, which is caused by the pressure-induced deformation of thin garnet windows in the chamber. The pressure dependence has excellent reproducibility even after many hundreds of cycles of letting in of air and its complete pumping out from the chamber. The accuracy of setting required thickness L is much better than in the wedge-gap NCs to be moved mechanically that were used earlier. The processes of Faraday rotation (FR) of a polarization plane, resonance absorption, and fluorescence are studied using the D 1-line narrow-band continuous laser radiation when the thickness changes from L = λ/2 (398 nm) to L = 2λ (1590 nm) at a step λ/2. The FR signal is shown to be maximal at L = λ/2 and 3λ/2 and to have the minimum spectral width (≈60 MHz). At L = λ and 2λ, the FR signal is minimal and has the maximum spectral width (≈200 MHz). The resonance absorption demonstrates the same oscillating behavior; however, the effect in the case of FR is much more pronounced. The oscillating effect is absent for resonance fluorescence: its spectral width and amplitude increase monotonically with L. The detected effects are explained and possible applications are noted.

Piezoelectric energy harvesting from an L-shaped beam-mass structure

NASA Astrophysics Data System (ADS)

Erturk, Alper; Renno, Jamil M.; Inman, Daniel J.

2008-03-01

Cantilevered piezoelectric harvesters have been extensively considered in the energy harvesting literature. Mostly, a traditional cantilevered beam with one or more piezoceramic layers is located on a vibrating host structure. Motion of the host structure results in vibrations of the harvester beam and that yields an alternating voltage output. As an alternative to classical cantilevered beams, this paper presents a novel harvesting device; a flexible L-shaped beam-mass structure that can be tuned to have a two-to-one internal resonance to a primary resonance ω II ≅ 2ω I which is not possible for classical cantilevers). The L-shaped structure has been well investigated in the literature of nonlinear dynamics since the two-to-one internal resonance, along with the consideration of quadratic nonlinearities, may yield modal energy exchange (for excitation frequency ω≅ ω Ior the so-called saturation phenomenon (for ω≅ω II). As a part of our ongoing research on piezoelectric energy harvesting, we are investigating the possibility of improving the electrical outputs in energy harvesting by employing these features of the L-shaped structure. This paper aims to introduce the idea, describes the important features of the L-shaped harvester configuration and develops a linear distributed parameter model for predicting the electromechanically coupled response. In addition, this work proposes a direct application of the L-shaped piezoelectric energy harvester configuration for use as landing gears in unmanned air vehicle applications.

Cardiac structure and function in the obese: a cardiovascular magnetic resonance imaging study.

PubMed

Danias, Peter G; Tritos, Nicholas A; Stuber, Matthias; Kissinger, Kraig V; Salton, Carol J; Manning, Warren J

2003-07-01

Obesity is a major health problem in the Western world. Among obese subjects cardiac pathology is common, but conventional noninvasive imaging modalities are often suboptimal for detailed evaluation of cardiac structure and function. We investigated whether cardiovascular magnetic resonance imaging (CMR) can better characterize possible cardiac abnormalities associated with obesity, in the absence of other confounding comorbidities. In this prospective cross-sectional study, CMR was used to quantify left and right ventricular volumes, ejection fraction, mass, cardiac output, and apical left ventricular rotation in 25 clinically healthy obese men and 25 age-matched lean controls. Obese subjects had higher left ventricular mass (203 +/- 38 g vs. 163 +/- 22 g, p < 0.001), end-diastolic volume (176 +/- 29 mL vs. 156 +/- 25 mL, p < 0.05), and cardiac output (8.2 +/- 1.2 L/min vs. 6.4 +/- 1.3 L/min, p < 0.001). The obese also had increased right ventricular mass (105 +/- 25 g vs. 87 +/- 18 g, p < 0.005) and end-diastolic volume (179 +/- 36 mL vs. 155 +/- 28 mL, p < 0.05). When indexed for height, differences in left and right ventricular mass, and left ventricular end-diastolic volume remained significant. Apical left ventricular rotation and rotational velocity patterns were also different between obese and lean subjects. Obesity is independently associated with remodeling of the heart. Cardiovascular magnetic resonance imaging identifies subtle cardiac abnormalities and may be the preferred imaging technique to evaluate cardiac structure and function in the obese.

Improving the Optical Quality Factor of the WGM Resonator

NASA Technical Reports Server (NTRS)

Savchenkov, Anatoliy; Matsko, Andrey; Iltchenko, Vladimir

2008-01-01

Resonators usually are characterized with two partially dependent values: finesse (F) and quality factor (Q). The finesse of an empty Fabry-Perot (FP) resonator is defined solely by the quality of its mirrors and is calculated as F=piR(exp 1/2)/(1-R). The maximum up-to-date value of reflectivity R approximately equal to 1 - 1.6 x 10(exp -6) is achieved with dielectric mirrors. An FP resonator made with the mirrors has finesse F=1.9 x 10(exp 6). Further practical increase of the finesse of FP resonators is problematic because of the absorption and the scattering of light in the mirror material through fundamental limit on the reflection losses given by the internal material losses and by thermodynamic density fluctuations on the order of parts in 109. The quality factor of a resonator depends on both its finesse and its geometrical size. A one-dimensional FP resonator has Q=2 F L/lambda, where L is the distance between the mirrors and lambda is the wavelength. It is easy to see that the quality factor of the resonator is unlimited because L is unlimited. F and Q are equally important. In some cases, finesse is technically more valuable than the quality factor. For instance, buildup of the optical power inside the resonator, as well as the Purcell factor, is proportional to finesse. Sometimes, however, the quality factor is more valuable. For example, inverse threshold power of intracavity hyperparametric oscillation is proportional to Q(exp 2) and efficiency of parametric frequency mixing is proportional to Q(exp 3). Therefore, it is important to know both the maximally achievable finesse and quality factor values of a resonator. Whispering gallery mode (WGM) resonators are capable of achieving larger finesse compared to FP resonators. For instance, fused silica resonators with finesse 2.3 x 10(exp 6) and 2.8 x 10(exp 6) have been demonstrated. Crystalline WGM resonators reveal even larger finesse values, F=6.3 x 10(exp 6), because of low attenuation of light in the transparent optical crystals. The larger values of F and Q result in the enhancement of various nonlinear processes. Low-threshold Raman lasing, optomechanical oscillations, frequency doubling, and hyperparametric oscillations based on these resonators have been recently demonstrated. Theory predicts a possibility of nearly 10(exp 14) room-temperature optical Q-factors of optical crystalline WGM resonators, which correspond to finesse levels higher than 10(exp 9). Experiments have shown numbers a thousand times lower than that. The difference occurs due to media imperfections. To substantially reduce the optical losses caused by the imperfections, a specific, multi-step, asymptotic processing of the resonator is implemented. The technique has been initially developed to reduce microwave absorption in dielectric resonators. One step of the process consists of mechanical polishing performed after high temperature annealing. Several steps repeat one after another to lead to significant reduction in optical attenuation and, as a result, to the increase of Q-factor as well as finesse of the resonator which demonstrates a CaF2 WGM resonator with F greater than 10(exp 7) and Q greater than 10(exp 11).

Ventricular kinetic energy may provide a novel noninvasive way to assess ventricular performance in patients with repaired tetralogy of Fallot.

PubMed

Jeong, Daniel; Anagnostopoulos, Petros V; Roldan-Alzate, Alejandro; Srinivasan, Shardha; Schiebler, Mark L; Wieben, Oliver; François, Christopher J

2015-05-01

Ventricular kinetic energy measurements may provide a novel imaging biomarker of declining ventricular efficiency in patients with repaired tetralogy of Fallot. Our purpose was to assess differences in ventricular kinetic energy with 4-dimensional flow magnetic resonance imaging between patients with repaired tetralogy of Fallot and healthy volunteers. Cardiac magnetic resonance, including 4-dimensional flow magnetic resonance imaging, was performed at rest in 10 subjects with repaired tetralogy of Fallot and 9 healthy volunteers using clinical 1.5T and 3T magnetic resonance imaging scanners. Right and left ventricular kinetic energy (KERV and KELV), main pulmonary artery flow (QMPA), and aortic flow (QAO) were quantified using 4-dimensional flow magnetic resonance imaging data. Right and left ventricular size and function were measured using standard cardiac magnetic resonance techniques. Differences in peak systolic KERV and KELV in addition to the QMPA/KERV and QAO/KELV ratios between groups were assessed. Kinetic energy indices were compared with conventional cardiac magnetic resonance parameters. Peak systolic KERV and KELV were higher in patients with repaired tetralogy of Fallot (6.06 ± 2.27 mJ and 3.55 ± 2.12 mJ, respectively) than in healthy volunteers (5.47 ± 2.52 mJ and 2.48 ± 0.75 mJ, respectively), but were not statistically significant (P = .65 and P = .47, respectively). The QMPA/KERV and QAO/KELV ratios were lower in patients with repaired tetralogy of Fallot (7.53 ± 5.37 mL/[cycle mJ] and 9.65 ± 6.61 mL/[cycle mJ], respectively) than in healthy volunteers (19.33 ± 18.52 mL/[cycle mJ] and 35.98 ± 7.66 mL/[cycle mJ], respectively; P < .05). QMPA/KERV and QAO/KELV were weakly correlated to ventricular size and function. Greater ventricular kinetic energy is necessary to generate flow in the pulmonary and aortic circulations in repaired tetralogy of Fallot. Quantification of ventricular kinetic energy in patients with repaired tetralogy of Fallot is a new observation. Future studies are needed to determine whether changes in ventricular kinetic energy can provide earlier evidence of ventricular dysfunction and guide future medical and surgical interventions. Copyright © 2015 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.

Magnetic Resonance Spectroscopy: An Objective Technique for the Quantification of Prostate Cancer Pathologies

DTIC Science & Technology

2007-02-01

5d. PROJECT NUMBER Leo L. Cheng, Ph.D. 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S...Scott RM, Anthony DC, Gonzalez RG, Black PM. Biochemical characterization of pediatric brain tumors by using in vivo and ex vivo magnetic resonance...Biochemical characterization of pediatric brain tumors by using in vivo and ex vivo magnetic resonance spectroscopy. J Neurosurg 2002;96: 1023–1031. 7

Empiric physiology in epidemiologic doctrines of the 18th century, Hungarian General Norm of Health in 1770.

PubMed

Balázs, P

2006-03-01

According to standard textbooks, the last episode of European New Age plague pandemic died out by 1720 in Marseilles. Despite this allegation, the pandemic continued in well-documented new outbreaks, which attacked and devastated Central and Eastern Europe throughout the first half of the 18th century. At the beginning, military campaigns spread the infection out of the Ottoman Empire. Later on commercial goods took over this role via land or sea from Asia or out of the eastern Mediterranean region. Finally, the plague in Europe--except Russia and the Ottoman Empire--"died out" virtually by the end of the 18th century. Explaining this, there many scientific reasons were suggested: 1. Oriental rat fleas as main vectors of infection could not tolerate any more the European weather conditions (although there were no virtual climate changes in the last 300 years). 2. Black rats that lived in close proximity to man, were being outplayed by brown rats living rather outside of human habitats; 3. There emerged less virulent Yersinia strains that caused natural human immunisation. In spite of these suggestions, which may have contributed to the success, joint civil and military health authorities blocked the plague indeed, as a result of disciplined and relentless law enforcement. In Hungary, respectively in the Hapsburg Empire, well-advised health legislation backed up the effectiveness of local authorities. Following the last great devastation in 1738-1740, the General Norm of Health Service--a voluminous decree--summed up by 1770 all the time honoured empiric rules of foregoing centuries. It can be excellently demonstrated, how exactly the empiric rules discovered a century later met scientific facts of physiology and microbiology.

Timeline and bibliography of early isolations of plant metabolites (1770-1820) and their impact to pharmacy: A critical study.

PubMed

Drobnik, Jacek; Drobnik, Elżbieta

2016-10-27

Plant metabolites became objects of chemical research for pharmaceutical and medicinal reasons. The period of pure plant substances in chemistry started 1770 with isolation of tartaric acid from wine (wine in pharmacy is a plant-derived preparation). Carl Scheele isolated 7 plant acids: tartaric, benzoic, citric, oxalic, malic, glucuronic and gallic. The era of alkaloids started 1803 when narcotine was discovered and published. Since that time, pharmacists and toxicologists began to recognize alkaloids (or substances regarded as such) as highly active principles responsible for their powerful, thus easily-observed actions to humans and test animals. By 1820 when solanine was isolated, pharmaceutical chemistry has dealt with increasing number of natural plant-derived substances as organic medicines or reagents. The following historical facts have been unknown: Scheele's tartaric acid was introduced officially as a medicinal substance as early as in 1775, benzoic, citric and oxalic acids became official by the end of the 18th century. Morphine was effectively published in 1806 (not 1804), hence the first alkaloid known in isolated state is narcotine (published 1803, official since 1827). Morphine became official in French pharmacy in 1818. And, 1814 is the year when 2 first toxicological accounts on plant-derived acids (oxalic and tartaric) appeared. Practical use in therapy, sometimes soon after discovery, inspired practical pharmacy and stimulated the progress of toxicology. We studied the earliest 50years of plant metabolites isolations era. A revised bibliography and a timeline chart for 24 plant substances from this period is provided. Plants from original publications are taxonomically identified. Copyright © 2016 Elsevier B.V. All rights reserved.

MET exon 14 skipping defines a unique molecular class of non-small cell lung cancer.

PubMed

Zheng, Difan; Wang, Rui; Ye, Ting; Yu, Su; Hu, Haichuan; Shen, Xuxia; Li, Yuan; Ji, Hongbin; Sun, Yihua; Chen, Haiquan

2016-07-05

Recurrent MET exon 14 splicing has been revealed in lung cancers and is a promising therapeutic target. Because we have limited knowledge about the natural history of MET mutant tumors, the current study was aiming to determine the clinical and pathological characteristics in non-small cell lung cancers (NSCLC). Twenty-three patients (1.3%) were positive for MET exon 14 skipping. Patients with MET exon 14 skipping displayed unique characteristics: female, non-smokers, earlier pathology stage and older age. MET exon 14 skipping indicated an early event as other drivers in lung cancer, while MET copy number gain was more likely a late event in lung cancer. Overall survival (OS) of patients harboring MET exon 14 skipping was longer than patients with KRAS mutation. Almost four-fifths of the lung tumors with MET exon 14 skipping had EGFR and/or HER2 gene copy number gains. EGFR inhibitor showed moderate antitumor activity in treatment of a patient harboring MET exon 14 skipping. From October 2007 to June 2013, we screened 1770 patients with NSCLC and correlated MET status with clinical pathologic characteristics and mutations in EGFR, KRAS, BRAF, HER2, and ALK. Quantitative Real-Time PCR was used to detect MET gene copy number gain. Immunohistochemistry (IHC) was also performed to screen MET exon 14 skipping. Clinicopathological characteristics and survival information were analyzed. MET exon 14 skipping was detected in 1.3% (23/1770) of the Chinese patients with NSCLC. MET exon 14 skipping defined a new molecular subset of NSCLC with identifiable clinical characteristics. The therapeutic EGFR inhibitors might be an alternative treatment for patients with MET mutant NSCLC.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yokosawa, A.

Recent data are presented on spin-spin correlation parameters C/sub LL/ = (L,L;0,0) and C/sub SL/ = (S,L;0.0) up to 2.47 GeV/c incident momentum in proton-proton elastic scattering. These data will be useful in clarifying ambiguities in phase-shift analyses, and in confirming diproton resonances. 11 references, 2 figures.

Polarization Dependence of Resonant Inelastic Scattering in Insulating Copper Oxides

NASA Astrophysics Data System (ADS)

Hill, John

2000-03-01

Recent work on a number of copper oxides, including Nd_2CuO_4, YBa_2Cu_3O7 and CuGeO3 is reported. In each case, an excitation of ~ 6 eV is observed when the incident energy is tuned through the Cu K-edge. Numerical calculations based on the Anderson Impurity model for Nd_2CuO4 suggest that this feature is a charge-transfer excitation to the antibonding state. Studies of the incident energy and polarization dependence of this excitation in Nd_2CuO4 reveal that the incident polarization selects the intermediate states participating in the resonance process. In particular, when the incident polarization is largely perpendicular to the copper oxide planes, a single resonance is observed at 8990 eV, corresponding to the \\underline 1s3d^94p_π intermediate state. Conversely with the incident polarization is aligned with the planes, an enhancement is observed at 8999.5 eV, associated with the \\underline 1s3d^94p_σ intermediate state. No enhancement is observed for the \\underline 1s3d^10\\underline L 4p intermediate state in either case. It is suggested that the systematic absence of this resonance is associated with non-local effects active in this intermediate state. This suggestion is supported by multi-copper-site calculations, and by our studies of CuGeO_3. In this latter compound, the CuO4 plaquettes are arranged in one dimensional edge-sharing chains, rather than the two dimensional corner sharing network of Nd_2CuO_4. Non-local effects are expected to be suppressed in such a case, and indeed two resonances are observed in CuGeO_3. This work further suggests that this technique may provide both a sensitive measure of the role of non-local effects in the excitation spectrum, and a stringent test for state-of-the-art electronic structure calculations. It is a great pleasure to acknowledge my collaborators in this work, L.E. Berman, W.A.L. Caliebe, R.L. Greene, K. Hämäläinen, K. Hirota, S. Huotari, T. Idé. C.-C. Kao, A. Kotani, T. Masuda, M. Matsubara, J.L. Peng, I. Tsukada, K. Uchinokura, and M. v. Zimmermann.

The effect of vegetarian diets on iron status in adults: A systematic review and meta-analysis.

PubMed

Haider, Lisa M; Schwingshackl, Lukas; Hoffmann, Georg; Ekmekcioglu, Cem

2018-05-24

Vegetarian diets exclude meat, seafood, and products containing these foods. Although the vegetarian lifestyle could lead to a better health status in adults, it may also bear risks for certain nutritional deficiencies. Cross-sectional studies and narrative reviews have shown that the iron status of vegetarians is compromised by the absence of highly bioavailable haem-iron in meatless diets and the inhibiting effect of certain components present in plant foods on non-haem iron bioavailability. The databases Pubmed, Scopus, Embase, and Cochrane CentralRegister of Controlled Trials were searched for studies comparing serum ferritin, as the major laboratory parameter for iron status of adult vegetarians with non-vegetarian control groups. A qualitative review was conducted as well as an inverse-variance random-effects meta-analysis to pool available data. In addition the effect of vegetarian diets according to gender was investigated with a subgroup analysis. The results were validated using a sensitivity analysis. A total of 27 cross-sectional studies and three interventional studies were selected for the systematic review. The meta-analysis which combined data of 24 cross-sectional studies showed that adult vegetarians have significantly lower serum ferritin levels than their non-vegetarian controls (-29.71 µg/L, 95% CI [-39.69, -19.73], p < 0.01). Inclusion of semi-vegetarian diets did not change the results considerably (-23.27 µg/L, 95% CI [-29.77, -16.76], p < 0.01). The effects were more pronounced in men (-61.88 µg/L, 95% CI [-85.59, -38.17], p < 0.01) than in both premenopausal women (-17.70 μg/L, 95% CI [-29.80, -5.60], p < 0.01) and all women (-13.50 μg/L, 95% CI [-22.96, -4.04], p < 0.01), respectively. In conclusion our results showed that vegetarians are more likely to have lower iron stores compared with non-vegetarians. However, since high iron stores are also a risk factor for certain non-communicable diseases, such as type 2 diabetes, it is recommended that not only vegetarians but also non-vegetarians should regularly control their iron status and improve their diet regarding the content and bioavailability of iron by consuming more plants and less meat.

Broadband reflective multi-polarization converter based on single-layer double-L-shaped metasurface

NASA Astrophysics Data System (ADS)

Mao, Chenyang; Yang, Yang; He, Xiaoxiang; Zheng, Jingming; Zhou, Chun

2017-12-01

In this paper, a broadband reflective multi-polarization converter based on single-layer double-L-shaped metasurface is proposed. The proposed metasurface can effectively convert linear-polarized (TE/TM) incident wave into the reflected wave with three different polarizations within the frequency bands of 5.5-22.75 GHz. Based on the electric and magnetic resonant features of the double-L-shaped structure, the proposed metasurface can convert linearly polarized waves into cross-polarized waves at three resonant frequency bands. Furthermore, the incident linearly polarized waves can be effectively converted into left/right handed circular-polarized (LHCP and RHCP) waves at other four non-resonance frequency bands. Thus, the proposed metasurface can be regarded as a seven-band multi-polarization converter. The prototype of the proposed polarization converter is analyzed and measured. Both simulated and measured results show the 3-dB axis ratio bandwidth of circular polarization bands and the high polarization conversion efficiency of cross-polarization bands when the incident wave changes from 0° to 30° at both TE and TM modes.

Magnetic resonance imaging for staging and treatment planning in cervical cancer.

PubMed

López-Carballeira, A; Baleato-González, S; García-Figueiras, R; Otero-Estévez, I; Villalba-Martín, C

2016-01-01

To review the key points that are essential for the correct staging of cervical cancer by magnetic resonance imaging. Magnetic resonance imaging is the method of choice for locoregional staging of cervical cancer. Thorough evaluation of prognostic factors such as tumor size, invasion of adjacent structures, and the presence of lymph node metastases is fundamental for planning appropriate treatment. Copyright © 2015 SERAM. Publicado por Elsevier España, S.L.U. All rights reserved.

Exciton band structure in layered MoSe2: from a monolayer to the bulk limit.

PubMed

Arora, Ashish; Nogajewski, Karol; Molas, Maciej; Koperski, Maciej; Potemski, Marek

2015-12-28

We present the micro-photoluminescence (μPL) and micro-reflectance contrast (μRC) spectroscopy studies on thin films of MoSe(2) with layer thicknesses ranging from a monolayer (1L) up to 5L. The thickness dependent evolution of the ground and excited state excitonic transitions taking place at various points of the Brillouin zone is determined. Temperature activated energy shifts and linewidth broadenings of the excitonic resonances in 1L, 2L and 3L flakes are accounted for by using standard formalisms previously developed for semiconductors. A peculiar shape of the optical response of the ground state (A) exciton in monolayer MoSe(2) is tentatively attributed to the appearance of a Fano-type resonance. Rather trivial and clearly decaying PL spectra of monolayer MoSe(2) with temperature confirm that the ground state exciton in this material is optically bright in contrast to a dark exciton ground state in monolayer WSe(2).

Exciton band structure in layered MoSe2: from a monolayer to the bulk limit

NASA Astrophysics Data System (ADS)

Arora, Ashish; Nogajewski, Karol; Molas, Maciej; Koperski, Maciej; Potemski, Marek

2015-12-01

We present the micro-photoluminescence (μPL) and micro-reflectance contrast (μRC) spectroscopy studies on thin films of MoSe2 with layer thicknesses ranging from a monolayer (1L) up to 5L. The thickness dependent evolution of the ground and excited state excitonic transitions taking place at various points of the Brillouin zone is determined. Temperature activated energy shifts and linewidth broadenings of the excitonic resonances in 1L, 2L and 3L flakes are accounted for by using standard formalisms previously developed for semiconductors. A peculiar shape of the optical response of the ground state (A) exciton in monolayer MoSe2 is tentatively attributed to the appearance of a Fano-type resonance. Rather trivial and clearly decaying PL spectra of monolayer MoSe2 with temperature confirm that the ground state exciton in this material is optically bright in contrast to a dark exciton ground state in monolayer WSe2.

Monoamine oxidase B layer-by-layer film fabrication and characterization toward dopamine detection.

PubMed

Miyazaki, Celina Massumi; Pereira, Tamyris Paschoal; Mascagni, Daniela Branco Tavares; de Moraes, Marli Leite; Ferreira, Marystela

2016-01-01

In this work nanostructured film composites of the monoamine oxidase B (MAO-B) enzyme, free or encapsulated in liposomes, were fabricated by the layer-by-layer (LbL) self-assembly technique, employing polyethylene imine (PEI) as polycation. Initially, the MAO-B enzyme was incorporated into liposomes in order to preserve its enzymatic structure ensuring their activity and catalytic stability. The LbL film growth was monitored by surface plasmon resonance (SPR) by gold resonance angle shift analysis after each bilayer deposition. Subsequently, the films were applied as amperometric biosensors for dopamine detection using Prussian Blue (PB) as the electron mediator. The biosensor fabricated by MAO-B incorporated into liposomes composed of DPPG:POPG in the ratio (1:4) (w/w) showed the best performance with a sensitivity of 0.86 (μA cm(-2))/(mmol L(-1)) and a detection limit of 0.33 mmol L(-1).

The sun and exoplanets: The solitude of man

NASA Astrophysics Data System (ADS)

Kotov, V. A.

2012-06-01

Solar pulsations with a period of P 0 = 9600.606(12) were discovered in 1974. A more recent discovery is that planetary distances in the solar system are subject to spatial resonance with the parameter L 0 ≡ cP 0 ≈ 9600 ls and that the P 0 pulsation itself has cosmological significance (coherent cosmic oscillation, or the pace of absolute time of the universe; c is the speed of light). As of June 2011, 552 extrasolar planets have been discovered. Statistical analysis shows that the distribution of the semimajor axes of alien planets does not have L 0 resonance. Moreover, it appears to have no resonance at all. This frustrates the 20th-century hopes for the existence of extraterrestrial civilizations and possible contact with them. They are simply not there. This explanation of the Fermi paradox, or the Great Silence, appears to rest on the triumph of the anthropic principle, which has been successfully implemented by nature within our planetary system. This leads to a vision whereby the cosmos seems to be created specially for us. The scale L 0 indicates that the sun is a special quantum object, where L 0 is a wave function parameter that is not subject to the rational principles of the classical world, but rather follows a peculiar, quantum logic.

The Nobel Prize in Medicine for Magnetic Resonance Imaging

NASA Astrophysics Data System (ADS)

Fry, Charles G.

2004-07-01

A review is given of the crucial work performed by Paul C. Lauterbur and Peter Mansfield that lead to their being awarded the Nobel Prize in Medicine in 2003. Lauterbur first expounded the idea of mapping spatial information from spectral data in nuclear magnetic resonance (NMR) through the application of magnetic field gradients (P. C. Lauterbur, Nature 1973 , 242, 190-191). One year later Mansfield and co-workers introduced the idea of selective excitation to NMR imaging (A. N. Garroway, P. K. Grannell, and P. Mansfield. J. Phys. C: Solid State Physics 1974 , 7, L457-L462). A major step in making the technique useful for clinical imaging came with Mansfield's publication of the method known as echo planar imaging (P. Mansfield, J. Phys. C: Solid State Physics 1977, 10 (3) , L55-L58). Lauterbur's and Mansfield's work captured the essence of scientific discovery, collaboration, and concerted effort to overcome significant technical issues, and were key to the development of the technique of magnetic resonance imaging (MRI). Examples of how MRI technology can be extended to chemical research are given, and limitations of the technique in this regard are discussed. Discussion of how to use commonly available NMR spectrometers for chemical imaging is also provided.

Renal MR angiography and perfusion in the pig using hyperpolarized water.

PubMed

Wigh Lipsø, Kasper; Hansen, Esben Søvsø Szocska; Tougaard, Rasmus Stilling; Laustsen, Christoffer; Ardenkjaer-Larsen, Jan Henrik

2017-09-01

To study hyperpolarized water as an angiography and perfusion tracer in a large animal model. Protons dissolved in deuterium oxide (D 2 O) were hyperpolarized in a SPINlab dissolution dynamic nuclear polarization (dDNP) polarizer and subsequently investigated in vivo in a pig model at 3 Tesla (T). Approximately 15 mL of hyperpolarized water was injected in the renal artery by hand over 4-5 s. A liquid state polarization of 5.3 ± 0.9% of 3.8 M protons in 15 mL of deuterium oxide was achieved with a T 1 of 24 ± 1 s. This allowed injection through an arterial catheter into the renal artery and subsequently high-contrast imaging of the entire kidney parenchyma over several seconds. The dynamic images allow quantification of tissue perfusion, with a mean cortical perfusion of 504 ± 123 mL/100 mL/min. Hyperpolarized water MR imaging was successfully demonstrated as a renal angiography and perfusion method. Quantitative perfusion maps of the kidney were obtained in agreement with literature and control experiments with gadolinium contrast. Magn Reson Med 78:1131-1135, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

Comparative analysis of magnetic resonance in the polaron pair recombination and the triplet exciton-polaron quenching models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mkhitaryan, V. V.; Danilovic, D.; Hippola, C.

We present a comparative theoretical study of magnetic resonance within the polaron pair recombination (PPR) and the triplet exciton-polaron quenching (TPQ) models. Both models have been invoked to interpret the photoluminescence detected magnetic resonance (PLDMR) results in π-conjugated materials and devices. We show that resonance line shapes calculated within the two models differ dramatically in several regards. First, in the PPR model, the line shape exhibits unusual behavior upon increasing the microwave power: it evolves from fully positive at weak power to fully negative at strong power. In contrast, in the TPQ model, the PLDMR is completely positive, showing amore » monotonic saturation. Second, the two models predict different dependencies of the resonance signal on the photoexcitation power, PL. At low PL, the resonance amplitude Δ I/I is ∝ PL within the PPR model, while it is ∝ P2L crossing over to P3L within the TPQ model. On the physical level, the differences stem from different underlying spin dynamics. Most prominently, a negative resonance within the PPR model has its origin in the microwave-induced spin-Dicke effect, leading to the resonant quenching of photoluminescence. The spin-Dicke effect results from the spin-selective recombination, leading to a highly correlated precession of the on-resonance pair partners under the strong microwave power. This effect is not relevant for TPQ mechanism, where the strong zero-field splitting renders the majority of triplets off resonance. On the technical level, the analytical evaluation of the line shapes for the two models is enabled by the fact that these shapes can be expressed via the eigenvalues of a complex Hamiltonian. This bypasses the necessity of solving the much larger complex linear system of the stochastic Liouville equations. Lastly, our findings pave the way towards a reliable discrimination between the two mechanisms via cw PLDMR.« less

Comparative analysis of magnetic resonance in the polaron pair recombination and the triplet exciton-polaron quenching models

DOE PAGES

Mkhitaryan, V. V.; Danilovic, D.; Hippola, C.; ...

2018-01-03

We present a comparative theoretical study of magnetic resonance within the polaron pair recombination (PPR) and the triplet exciton-polaron quenching (TPQ) models. Both models have been invoked to interpret the photoluminescence detected magnetic resonance (PLDMR) results in π-conjugated materials and devices. We show that resonance line shapes calculated within the two models differ dramatically in several regards. First, in the PPR model, the line shape exhibits unusual behavior upon increasing the microwave power: it evolves from fully positive at weak power to fully negative at strong power. In contrast, in the TPQ model, the PLDMR is completely positive, showing amore » monotonic saturation. Second, the two models predict different dependencies of the resonance signal on the photoexcitation power, PL. At low PL, the resonance amplitude Δ I/I is ∝ PL within the PPR model, while it is ∝ P2L crossing over to P3L within the TPQ model. On the physical level, the differences stem from different underlying spin dynamics. Most prominently, a negative resonance within the PPR model has its origin in the microwave-induced spin-Dicke effect, leading to the resonant quenching of photoluminescence. The spin-Dicke effect results from the spin-selective recombination, leading to a highly correlated precession of the on-resonance pair partners under the strong microwave power. This effect is not relevant for TPQ mechanism, where the strong zero-field splitting renders the majority of triplets off resonance. On the technical level, the analytical evaluation of the line shapes for the two models is enabled by the fact that these shapes can be expressed via the eigenvalues of a complex Hamiltonian. This bypasses the necessity of solving the much larger complex linear system of the stochastic Liouville equations. Lastly, our findings pave the way towards a reliable discrimination between the two mechanisms via cw PLDMR.« less

Highly excited bound-state resonances of short-range inverse power-law potentials

NASA Astrophysics Data System (ADS)

Hod, Shahar

2017-11-01

We study analytically the radial Schrödinger equation with long-range attractive potentials whose asymptotic behaviors are dominated by inverse power-law tails of the form V(r)=-β _n r^{-n} with n>2. In particular, assuming that the effective radial potential is characterized by a short-range infinitely repulsive core of radius R, we derive a compact analytical formula for the threshold energy E^{ {max}}_l=E^{ {max}}_l(n,β _n,R), which characterizes the most weakly bound-state resonance (the most excited energy level) of the quantum system.

The [4Fe-4S](2+) cluster in reconstituted biotin synthase binds S-adenosyl-L-methionine.

PubMed

Cosper, Michele Mader; Jameson, Guy N L; Davydov, Roman; Eidsness, Marly K; Hoffman, Brian M; Huynh, Boi Hanh; Johnson, Michael K

2002-11-27

The combination of resonance Raman, electron paramagnetic resonance and Mössbauer spectroscopies has been used to investigate the effect of S-adenosyl-l-methionine (SAM) on the spectroscopic properties of the [4Fe-4S]2+ cluster in biotin synthase. The results indicate that SAM interacts directly at a unique iron site of the [4Fe-4S]2+ cluster in BioB and support the hypothesis of a common inner-sphere mechanism for the reductive cleavage of SAM in the radical SAM family of Fe-S enzymes.

Smart Gold Nanobowls (Nano-Crescent Moon) with Sub-10 nm Circular Edge for Local Electromagnetic Field Enhancement Effect, Spatial, and NIR Temporal/Thermal Modulations for Molecular and Cellular Dynamic Imaging

DTIC Science & Technology

2006-01-31

nanoring [10], the Au nanocrescent has a higher local field enhancement factor in the near infrared wavelength region due to the simultaneous...incorporation of SERS hot spots including sharp nanotip and nanoring geometries and thus the strong hybrid resonance modes from nanocavity resonance mode and tip...Raman, "A change of wave-length in light scattering," Nature 121, 619-619 (1928). 22. Y. Lu, G. L. Liu, and L. P. Lee, "High-density silver nanoparticle

Trapped modes in a non-axisymmetric cylindrical waveguide

NASA Astrophysics Data System (ADS)

Lyapina, A. A.; Pilipchuk, A. S.; Sadreev, A. F.

2018-05-01

We consider acoustic wave transmission in a non-axisymmetric waveguide which consists of a cylindrical resonator and two cylindrical waveguides whose axes are shifted relatively to each other by an azimuthal angle Δϕ. Under variation of the resonator's length L and fixed Δϕ we find bound states in the continuum (trapped modes) due to full destructive interference of resonant modes leaking into the waveguides. Rotation of the waveguide adds complex phases to the coupling strengths of the resonator eigenmodes with the propagating modes of the waveguides tuning Fano resonances to give rise to a wave faucet. Under variation of Δϕ with fixed resonator's length we find symmetry protected trapped modes. For Δϕ ≠ 0 these trapped modes contribute to the scattering function supporting high vortical acoustic intensity spinning inside the resonator. The waveguide rotation brings an important feature to the scattering and provides an instrument for control of acoustic transmittance and wave trapping.

KSC00pp1770

NASA Image and Video Library

2000-11-18

KENNEDY SPACE CENTER, FLA. -- Lowered into the payload bay of the orbiter Atlantis, some of the STS-98 crew look over part of the payload. At center is Mission Specialist Robert Curbeam; at right are Mission Specialists Marsha Ivins (standing) and Tom Jones (kneeling). They and the rest of the crew are at KSC for Crew Equipment Interface Test activities. Launch on mission STS-98 is scheduled for Jan. 18, 2001. It will be transporting the U.S. Lab, Destiny, to the International Space Station with five system racks already installed inside of the module. After delivery of electronics in the lab, electrically powered attitude control for Control Moment Gyroscopes will be activated

KSC-00pp1770

NASA Image and Video Library

2000-11-18

KENNEDY SPACE CENTER, FLA. -- Lowered into the payload bay of the orbiter Atlantis, some of the STS-98 crew look over part of the payload. At center is Mission Specialist Robert Curbeam; at right are Mission Specialists Marsha Ivins (standing) and Tom Jones (kneeling). They and the rest of the crew are at KSC for Crew Equipment Interface Test activities. Launch on mission STS-98 is scheduled for Jan. 18, 2001. It will be transporting the U.S. Lab, Destiny, to the International Space Station with five system racks already installed inside of the module. After delivery of electronics in the lab, electrically powered attitude control for Control Moment Gyroscopes will be activated

Phosphodiester content measured in human liver by in vivo 31P MR spectroscopy at 7 tesla

PubMed Central

Clarke, William T.; Valkovič, Ladislav; Levick, Christina; Pavlides, Michael; Barnes, Eleanor; Cobbold, Jeremy F.; Robson, Matthew D.; Rodgers, Christopher T.

2017-01-01

Purpose Phosphorus (31P) metabolites are emerging liver disease biomarkers. Of particular interest are phosphomonoester and phosphodiester (PDE) “peaks” that comprise multiple overlapping resonances in 31P spectra. This study investigates the effect of improved spectral resolution at 7 Tesla (T) on quantifying hepatic metabolites in cirrhosis. Methods Five volunteers were scanned to determine metabolite T1s. Ten volunteers and 11 patients with liver cirrhosis were scanned at 7T. Liver spectra were acquired in 28 min using a 16‐channel 31P array and 3D chemical shift imaging. Concentrations were calculated using γ‐adenosine‐triphosphate (γ‐ATP) = 2.65 mmol/L wet tissue. Results T1 means ± standard deviations: phosphatidylcholine 1.05 ± 0.28 s, nicotinamide‐adenine‐dinucleotide (NAD+) 2.0 ± 1.0 s, uridine‐diphosphoglucose (UDPG) 3.3 ± 1.4 s. Concentrations in healthy volunteers: α‐ATP 2.74 ± 0.11 mmol/L wet tissue, inorganic phosphate 2.23 ± 0.20 mmol/L wet tissue, glycerophosphocholine 2.34 ± 0.46 mmol/L wet tissue, glycerophosphoethanolamine 1.50 ± 0.28 mmol/L wet tissue, phosphocholine 1.06 ± 0.16 mmol/L wet tissue, phosphoethanolamine 0.77 ± 0.14 mmol/L wet tissue, NAD+ 2.37 ± 0.14 mmol/L wet tissue, UDPG 2.00 ± 0.22 mmol/L wet tissue, phosphatidylcholine 1.38 ± 0.31 mmol/L wet tissue. Inorganic phosphate and phosphatidylcholine concentrations were significantly lower in patients; glycerophosphoethanolamine concentrations were significantly higher (P < 0.05). Conclusion We report human in vivo hepatic T1s for phosphatidylcholine, NAD+, and UDPG for the first time at 7T. Our protocol allows high signal‐to‐noise, repeatable measurement of metabolite concentrations in human liver. The splitting of PDE into its constituent peaks at 7T may allow more insight into changes in metabolism. Magn Reson Med 78:2095–2105, 2017. © 2017 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. PMID:28244131

The effect of whole-body resonance vibration in a porcine model of spinal cord injury.

PubMed

Streijger, Femke; Lee, Jae H T; Chak, Jason; Dressler, Dan; Manouchehri, Neda; Okon, Elena B; Anderson, Lisa M; Melnyk, Angela D; Cripton, Peter A; Kwon, Brian K

2015-06-15

Whole-body vibration has been identified as a potential stressor to spinal cord injury (SCI) patients during pre-hospital transportation. However, the effect that such vibration has on the acutely injured spinal cord is largely unknown, particularly in the frequency domain of 5 Hz in which resonance of the spine occurs. The objective of the study was to investigate the consequences of resonance vibration on the injured spinal cord. Using our previously characterized porcine model of SCI, we subjected animals to resonance vibration (5.7±0.46 Hz) or no vibration for a period of 1.5 or 3.0 h. Locomotor function was assessed weekly and cerebrospinal fluid (CSF) samples were collected to assess different inflammatory and injury severity markers. Spinal cords were evaluated histologically to quantify preserved white and gray matter. No significant differences were found between groups for CSF levels of monocyte chemotactic protein-1, interleukin 6 (IL-6) and lL-8. Glial fibrillary acidic protein levels were lower in the resonance vibration group, compared with the non-vibrated control group. Spared white matter tissue was increased within the vibrated group at 7 d post-injury but this difference was not apparent at the 12-week time-point. No significant difference was observed in locomotor recovery following resonance vibration of the spine. Here, we demonstrate that exposure to resonance vibration for 1.5 or 3 h following SCI in our porcine model is not detrimental to the functional or histological outcomes. Our observation that a 3.0-h period of vibration at resonance frequency induces modest histological improvement at one week post-injury warrants further study.

Electromechanical Frequency Filters

NASA Astrophysics Data System (ADS)

Wersing, W.; Lubitz, K.

Frequency filters select signals with a frequency inside a definite frequency range or band from signals outside this band, traditionally afforded by a combination of L-C-resonators. The fundamental principle of all modern frequency filters is the constructive interference of travelling waves. If a filter is set up of coupled resonators, this interference occurs as a result of the successive wave reflection at the resonators' ends. In this case, the center frequency f c of a filter, e.g., set up of symmetrical λ/2-resonators of length 1, is given by f_c = f_r = v_{ph}/λ = v_{ph}/2l , where v ph is the phase velocity of the wave. This clearly shows the big advantage of acoustic waves for filter applications in comparison to electro-magnetic waves. Because v ph of acoustic waves in solids is about 104-105 smaller than that of electro-magnetic waves, much smaller filters can be realised. Today, piezoelectric materials and processing technologies exist that electromechanical resonators and filters can be produced in the frequency range from 1 kHz up to 10 GHz. Further requirements for frequency filters such as low losses (high resonator Q) and low temperature coefficients of frequency constants can also be fulfilled with these filters. Important examples are quartz-crystal resonators and filters (1 kHz-200 MHz) as discussed in Chap. 2, electromechanical channel filters (50 kHz and 130 kHz) for long-haul communication systems as discussed in this section, surface acoustic wave (SAW) filters (20 MHz-5 GHz), as discussed in Chap. 14, and thin film bulk acoustic resonators (FBAR) and filters (500 MHz-10 GHz), as discussed in Chap. 15.

Periodic modulation-based stochastic resonance algorithm applied to quantitative analysis for weak liquid chromatography-mass spectrometry signal of granisetron in plasma

NASA Astrophysics Data System (ADS)

Xiang, Suyun; Wang, Wei; Xiang, Bingren; Deng, Haishan; Xie, Shaofei

2007-05-01

The periodic modulation-based stochastic resonance algorithm (PSRA) was used to amplify and detect the weak liquid chromatography-mass spectrometry (LC-MS) signal of granisetron in plasma. In the algorithm, the stochastic resonance (SR) was achieved by introducing an external periodic force to the nonlinear system. The optimization of parameters was carried out in two steps to give attention to both the signal-to-noise ratio (S/N) and the peak shape of output signal. By applying PSRA with the optimized parameters, the signal-to-noise ratio of LC-MS peak was enhanced significantly and distorted peak shape that often appeared in the traditional stochastic resonance algorithm was corrected by the added periodic force. Using the signals enhanced by PSRA, this method extended the limit of detection (LOD) and limit of quantification (LOQ) of granisetron in plasma from 0.05 and 0.2 ng/mL, respectively, to 0.01 and 0.02 ng/mL, and exhibited good linearity, accuracy and precision, which ensure accurate determination of the target analyte.

Note: Resonance magnetoelectric interactions in laminate of FeCuNbSiB and multilayer piezoelectric stack for magnetic sensor

NASA Astrophysics Data System (ADS)

Li, Jianqiang; Lu, Caijiang; Xu, Changbao; Zhong, Ming

2015-09-01

This paper develops a simple miniature magnetoelectric (ME) laminate FeCuNbSiB/PZT-stack made up of magnetostrictive Fe73.5Cu1Nb3Si13.5B9 (FeCuNbSiB) foils and piezoelectric Pb(Zr, Ti)O3 (PZT) multilayer stack vibrator. Resonant ME interactions of FeCuNbSiB/PZT-stack with different layers of FeCuNbSiB foil (L) are investigated in detail. The experimental results show that the ME voltage coefficient reaches maximum value of 141.5 (V/cm Oe) for FeCuNbSiB/PZT-stack with L = 6. The AC-magnetic sensitivities can reach 524.29 mV/Oe and 1.8 mV/Oe under resonance 91.6 kHz and off-resonance 1 kHz, respectively. The FeCuNbSiB/PZT-stack can distinguish small dc-magnetic field of ˜9 nT. The results indicate that the proposed ME composites are very promising for the cheap room-temperature magnetic field sensing technology.

Cross sections for the reactions e + e - → K S 0 K L 0 π 0 , K S 0 K L 0 η , and K S 0 K L 0 π 0 π 0 from events with initial-state radiation

DOE PAGES

Lees, J. P.; Poireau, V.; Tisserand, V.; ...

2017-03-06

Here, we study the processes e + e - → Kmore » $$0\\atop{S}$$ K$$0\\atop{L}$$ π 0 γ , K $$0\\atop{S}$$ K$$0\\atop{L}$$ η γ , and K$$0\\atop{S}$$ K$$0\\atop{L}$$ π 0 π 0 γ , where the photon is radiated from the initial state, providing cross section measurements for the hadronic final states over a continuum of center-of-mass energies. The results are based on 469 fb -1 of data collected at or near the Υ ( 4 S ) resonance with the BABAR detector at SLAC. We present the first measurements of the e + e - → K$$0\\atop{S}$$ K$$0\\atop{L}$$ π 0 , K$$0\\atop{S}$$ K$$0\\atop{L}$$ η , and K$$0\\atop{S}$$ K$$0\\atop{L}$$ π 0π 0 cross sections up to a center-of-mass energy of 4 GeV and study their intermediate resonance structures. We observe J / ψ decays to all of these final states for the first time, present measurements of their J / ψ branching fractions, and search for ψ (2S) decays.« less

Cross sections for the reactions e + e - → K S 0 K L 0 π 0 , K S 0 K L 0 η , and K S 0 K L 0 π 0 π 0 from events with initial-state radiation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lees, J. P.; Poireau, V.; Tisserand, V.

Here, we study the processes e + e - → Kmore » $$0\\atop{S}$$ K$$0\\atop{L}$$ π 0 γ , K $$0\\atop{S}$$ K$$0\\atop{L}$$ η γ , and K$$0\\atop{S}$$ K$$0\\atop{L}$$ π 0 π 0 γ , where the photon is radiated from the initial state, providing cross section measurements for the hadronic final states over a continuum of center-of-mass energies. The results are based on 469 fb -1 of data collected at or near the Υ ( 4 S ) resonance with the BABAR detector at SLAC. We present the first measurements of the e + e - → K$$0\\atop{S}$$ K$$0\\atop{L}$$ π 0 , K$$0\\atop{S}$$ K$$0\\atop{L}$$ η , and K$$0\\atop{S}$$ K$$0\\atop{L}$$ π 0π 0 cross sections up to a center-of-mass energy of 4 GeV and study their intermediate resonance structures. We observe J / ψ decays to all of these final states for the first time, present measurements of their J / ψ branching fractions, and search for ψ (2S) decays.« less

Damping Resonant Current in a Spark-Gap Trigger Circuit to Reduce Noise

DTIC Science & Technology

2009-06-01

DAMPING RESONANT CURRENT IN A SPARK- GAP TRIGGER CIRCUIT TO REDUCE NOISE E. L. Ruden Air Force Research Laboratory, Directed Energy Directorate, AFRL...REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE Damping Resonant Current In A Spark- Gap Trigger Circuit To Reduce Noise 5a...thereby triggering 2 after delay 0, is 1. Each of the two rail- gaps (represented by 2) is trig- gered to close after the spark- gap (1) in the

Mn(II) based T1 and T2 potential MRI contrast agent appended with tryptamine: Recognition moiety for Aβ-plaques.

PubMed

Rastogi, Neeraj; Tyagi, Nidhi; Singh, Ovender; Hemanth Kumar, B S; Singh, Udai P; Ghosh, Kaushik; Roy, Raja

2017-12-01

We report the synthesis and characterization of manganese(II) complexes having pentadentate ligands L 1 (2,6-bis(1-(2-phenyl-2-(pyridin-2-yl)hydrazono)ethyl)pyridine), L 2 (methyl 2,6-bis((E)-1-(2-phenyl-2-(pyridin-2yl)hydrazono)ethyl)isonicotinate), L 3 (N-(2-(1H-indol-3-yl)ethyl)-2,6-bis((E)-1-(2-phenyl-2-(pyridin2yl)hydrazono)ethyl)isonicotiamide) and their application as dual contrast agents for simultaneous T 1 and T 2 weighted magnetic resonance imaging. Single crystal analysis of all the complexes [Mn II L 1 , Mn II L 2 and Mn II L 3 ] confirm the formation of novel seven-coordinate manganese complexes with an inner sphere water and perchlorate ion. The Magnetic Resonance Imaging (MRI) contrast agent [MnL 2 ] was further modified by incorporating tryptamine as a binding moiety specific to Amyloid Beta-fibrils (Aβ-fibrils) in Alzhiemer's disease (AD) and it's in vitro evaluation for specific binding with Aβ-fibrils indicated as a bio-marker of AD. Copyright © 2017 Elsevier Inc. All rights reserved.

Experimental Investigation of 'Transonic Resonance' with Convergent-Divergent Nozzles

NASA Technical Reports Server (NTRS)

Zaman, K. B. M. Q.; Dahl, M. D.; Bencic, T. J.; Zaman, Khairul (Technical Monitor)

2001-01-01

Convergent-divergent nozzles, when run at pressure ratios lower than the design value, often undergo a flow resonance accompanied by the emission of acoustic tones. The phenomenon, different in characteristics from conventional 'screech' tones, has been studied experimentally. Unlike screech, the frequency increases with increasing supply pressure. There is a 'staging' behavior; 'odd harmonic' stages resonate at lower pressures while the fundamental occurs in a range of higher pressures corresponding to a fully expanded Mach number (M(sub j)) around unity. The frequency (f(sub N)) variation with M(sub j) depends on the half angle-of-divergence (theta) of the nozzle. At smaller theta, the slope of f(sub N) versus M(sub j) curve becomes steeper. The resonance involves standing waves and is driven by unsteady shock/boundary layer interaction. The distance between the foot of the shock and the nozzle exit imposes the lengthscale (L'). The fundamental corresponds to a quarterwave resonance, the next stage at a lower supply pressure corresponds to a three-quarter-wave resonance, and so on. The principal trends in the frequency variation are explained simply from the characteristic variation of the length-scale L'. Based on the data, correlation equations are provided for the prediction of f(sub N). A striking feature is that tripping of the boundary layer near the nozzle's throat tends to suppress the resonance. In a practical nozzle a tendency for the occurrence of the phenomenon is thought to be a source of 'internal noise'; thus, there is a potential for noise benefit simply by appropriate boundary layer tripping near the nozzle's throat.

Realizing a Circuit Analog of an Optomechanical System with Longitudinally Coupled Superconducting Resonators

NASA Astrophysics Data System (ADS)

Eichler, C.; Petta, J. R.

2018-06-01

We realize a superconducting circuit analog of the generic cavity-optomechanical Hamiltonian by longitudinally coupling two superconducting resonators, which are an order of magnitude different in frequency. We achieve longitudinal coupling by embedding a superconducting quantum interference device into a high frequency resonator, making its resonance frequency depend on the zero point current fluctuations of a nearby low frequency L C resonator. By applying sideband drive fields we enhance the intrinsic coupling strength of about 15 kHz up to 280 kHz by controlling the amplitude of the drive field. Our results pave the way towards the exploration of optomechanical effects in a fully superconducting platform and could enable quantum optics experiments with photons in the yet unexplored radio frequency band.

Double-quantum homonuclear rotary resonance: Efficient dipolar recovery in magic-angle spinning nuclear magnetic resonance

NASA Astrophysics Data System (ADS)

Nielsen, N. C.; Bildsøe, H.; Jakobsen, H. J.; Levitt, M. H.

1994-08-01

We describe an efficient method for the recovery of homonuclear dipole-dipole interactions in magic-angle spinning NMR. Double-quantum homonuclear rotary resonance (2Q-HORROR) is established by fulfilling the condition ωr=2ω1, where ωr is the sample rotation frequency and ω1 is the nutation frequency around an applied resonant radio frequency (rf) field. This resonance can be used for double-quantum filtering and measurement of homonuclear dipolar interactions in the presence of magic-angle spinning. The spin dynamics depend only weakly on crystallite orientation allowing good performance for powder samples. Chemical shift effects are suppressed to zeroth order. The method is demonstrated for singly and doubly 13C labeled L-alanine.

The importance of multi-level Rydberg interaction in electric field tuned Förster resonances

NASA Astrophysics Data System (ADS)

Kondo, Jorge; Booth, Donald; Gonçalves, Luis; Shaffer, James; Marcassa, Luis

2016-05-01

Many-body physics has been investigated in ultracold Rydberg atom systems, mainly because important parameters, such as density and interaction strength, can be controlled. Several puzzling experimental observations on Förster resonances have been associated to many-body effects, usually by comparison to complex theoretical models. In this work, we investigate the dc electric field dependence of 2 Förster resonant processes in ultracold 85 Rb, 37D5 / 2 + 37D5 / 2 --> 35 L(L = O , Q) + 39P3 / 2 , as a function of the atomic density in an optical dipole trap. At low densities, the 39 P yield as a function of electric field exhibits resonances. With increasing density, the linewidths increase until the peaks merge. Even under these extreme conditions, where many-body effects were expected to play a role, the 39 P population depends quadratically on the total Rydberg atom population. In order to explain our results, we implement a theoretical model which takes into account the multi-level character of the interactions and Rydberg atom blockade process using only atom pair interactions. The comparison between the experimental data and the model is very good, suggesting that the Förster resonant processes are dominated by 2-body interactions. This work is supported by FAPESP, AFOSR, NSF, INCT-IQ and CNPq.

Far off-resonance laser frequency stabilization using multipass cells in Faraday rotation spectroscopy.

PubMed

Quan, Wei; Li, Yang; Li, Rujie; Shang, Huining; Fang, Zishan; Qin, Jie; Wan, Shuangai

2016-04-01

We propose a far off-resonance laser frequency stabilization method by using multipass cells in Rb Faraday rotation spectroscopy. Based on the detuning equation, if multipass cells with several meters optical path length are used in the conventional Faraday spectroscopy, the detuning of the lock point can be extended much further from the alkali metal resonance. A plate beam splitter was used to generate two different Faraday signals at the same time. The transmitted optical path length was L=50  mm and the reflected optical path length was 2L=100  mm. When the optical path length doubled, the detuning of the lock points moved further away from the atomic resonance. The temperature dependence of the detuning of the lock point was also analyzed. A temperature-insensitive lock point was found near resonance when the cell temperature was between 110°C and 130°C. We achieved an rms fluctuation of 0.9 MHz/23 h at a detuning of 0.5 GHz. A frequency drift of 16 MHz/h at a detuning of -5.6  GHz and 4 MHz/h at a detuning of -5.2  GHz were also obtained for the transmitted and reflected light Faraday signal.

A revised set of values of single-bond radii derived from the observed interatomic distances in metals by correction for bond number and resonance energy

PubMed Central

Pauling, Linus; Kamb, Barclay

1986-01-01

An earlier discussion [Pauling, L. (1947) J. Am. Chem. Soc. 69, 542] of observed bond lengths in elemental metals with correction for bond number and resonance energy led to a set of single-bond metallic radii with values usually somewhat less than the corresponding values obtained from molecules and complex ions. A theory of resonating covalent bonds has now been developed that permits calculation of the number of resonance structures per atom and of the effective resonance energy per bond. With this refined method of correcting the observed bond lengths for the effect of resonance energy, a new set of single-bond covalent radii, in better agreement with values from molecules and complex ions, has been constructed. PMID:16593698

Nuclear Resonance Vibrational Spectra of Five-Coordinate Imidazole-ligated Iron(II) Porphyrinates

PubMed Central

Hu, Chuanjiang; Barabanschikov, Alexander; Ellison, Mary K.; Zhao, Jiyong; Alp, E. Ercan; Sturhahn, Wolfgang; Zgierski, Marek Z.; Sage, J. Timothy; Scheidt, W. Robert

2012-01-01

Nuclear resonance vibrational spectra have been obtained for six five-coordinate imidazole-ligated iron(II) porphyrinates, [Fe(Por)(L)] (Por = tetraphenylporphyrinate, octaethylporphyrinate, tetratolylporphyrinate or protoporphyrinate IX and L = 2-methylimidazole or 1,2-dimethylimidazole). Measurements have been made on both powder and oriented crystal samples. The spectra are dominated by strong signals around 200–300 cm−1. Although the in-plane and out-of-plane vibrations are seriously overlapped, oriented crystal spectra allow their deconvolution. Thus, oriented crystal experimental data, along with DFT calculations, enable the assignment of key vibrations in the spectra. Molecular dynamics are also discussed. The nature of the Fe–NIm vibrations has been elaborated further than was possible from resonance Raman studies. Our study suggests that the Fe motions are coupled with the porphyrin core and peripheral groups motions. Both peripheral groups and their conformations have significant influence on the vibrational spectra (position and shape). PMID:22243131

Wigner time delay and spin-orbit activated confinement resonances

NASA Astrophysics Data System (ADS)

Keating, D. A.; Deshmukh, P. C.; Manson, S. T.

2017-09-01

A study of the photoionization of spin-orbit split subshells of high-Z atoms confined in C60 has been performed using the relativistic-random-phase approximation. Specifically, Hg@C60 5p, Rn@C60 6p and Ra@C60 5d were investigated and the near-threshold confinement resonances in the j = l - 1/2 channels were found to engender structures in the j = l + 1/2 cross sections via correlation in the form of interchannel coupling. These structures are termed spin-orbit induced confinement resonances and they are found to profoundly influence the Wigner time delay spectrum resulting in time delays of tens or hundreds of attoseconds along with dramatic swings in time delay over small energy intervals. Pronounced relativistic effects in time delay are also found. These structures, including their manifestation in time delay spectra, are expected to be general phenomena in the photoionization of spin-orbit doublets in confined high-Z atoms.

Gravity resonance spectroscopy constrains dark energy and dark matter scenarios.

PubMed

Jenke, T; Cronenberg, G; Burgdörfer, J; Chizhova, L A; Geltenbort, P; Ivanov, A N; Lauer, T; Lins, T; Rotter, S; Saul, H; Schmidt, U; Abele, H

2014-04-18

We report on precision resonance spectroscopy measurements of quantum states of ultracold neutrons confined above the surface of a horizontal mirror by the gravity potential of Earth. Resonant transitions between several of the lowest quantum states are observed for the first time. These measurements demonstrate that Newton's inverse square law of gravity is understood at micron distances on an energy scale of 10-14  eV. At this level of precision, we are able to provide constraints on any possible gravitylike interaction. In particular, a dark energy chameleon field is excluded for values of the coupling constant β>5.8×108 at 95% confidence level (C.L.), and an attractive (repulsive) dark matter axionlike spin-mass coupling is excluded for the coupling strength gsgp>3.7×10-16 (5.3×10-16) at a Yukawa length of λ=20  μm (95% C.L.).

Manually controlled targeted prostate biopsy with real-time fusion imaging of multiparametric magnetic resonance imaging and transrectal ultrasound: an early experience.

PubMed

Shoji, Sunao; Hiraiwa, Shinichiro; Endo, Jun; Hashida, Kazunobu; Tomonaga, Tetsuro; Nakano, Mayura; Sugiyama, Tomoko; Tajiri, Takuma; Terachi, Toshiro; Uchida, Toyoaki

2015-02-01

To report our early experience with manually controlled targeted biopsy with real-time multiparametric magnetic resonance imaging and transrectal ultrasound fusion images for the diagnosis of prostate cancer. A total of 20 consecutive patients suspicious of prostate cancer at the multiparametric magnetic resonance imaging scan were recruited prospectively. Targeted biopsies were carried out for each cancer-suspicious lesion, and 12 systematic biopsies using the BioJet system. Pathological findings of targeted and systematic biopsies were analyzed. The median age of the patients was 70 years (range 52-83 years). The median preoperative prostate-specific antigen value was 7.4 ng/mL (range 3.54-19.9 ng/mL). Median preoperative prostate volume was 38 mL (range 24-68 mL). The number of cancer-detected cases was 14 (70%). The median Gleason score was 6.5 (range 6-8). Cancer-detected rates of the systematic and targeted biopsy cores were 6.7 and 31.8%, respectively (P < 0.0001). In six patients who underwent radical prostatectomy, the geographic locations and pathological grades of clinically significant cancers and index lesions corresponded to the pathological results of the targeted biopsies. Prostate cancers detected by targeted biopsies with manually controlled targeted biopsy using real-time multiparametric magnetic resonance imaging and transrectal ultrasound fusion imaging have significantly higher grades and longer length compared with those detected by systematic biopsies. Further studies and comparison with the pathological findings of whole-gland specimens have the potential to determine the role of this biopsy methodology in patients selected for focal therapy and those under active surveillance. © 2014 The Japanese Urological Association.

Extraction and characterization of montmorency (Prunus cerasus L.) sour cherry pit oil

USDA-ARS?s Scientific Manuscript database

Montmorency sour cherry (Prunus cerasus L.) pit oil was extracted and characterized by various methods including: gas chromatography (GC), liquid chromatography coupled with mass spectrometry (LC-MS), nuclear magnetic resonance (NMR), thermogravimetric analysis (TGA), differential scanning calorime...

Nanoscale resonant-cavity-enhanced germanium photodetectors with lithographically defined spectral response for improved performance at telecommunications wavelengths.

PubMed

Balram, Krishna C; Audet, Ross M; Miller, David A B

2013-04-22

We demonstrate the use of a subwavelength planar metal-dielectric resonant cavity to enhance the absorption of germanium photodetectors at wavelengths beyond the material's direct absorption edge, enabling high responsivity across the entire telecommunications C and L bands. The resonant wavelength of the detectors can be tuned linearly by varying the width of the Ge fin, allowing multiple detectors, each resonant at a different wavelength, to be fabricated in a single-step process. This approach is promising for the development of CMOS-compatible devices suitable for integrated, high-speed, and energy-efficient photodetection at telecommunications wavelengths.

Electronic structure differences between H(2)-, Fe-, Co-, and Cu-phthalocyanine highly oriented thin films observed using NEXAFS spectroscopy.

PubMed

Willey, T M; Bagge-Hansen, M; Lee, J R I; Call, R; Landt, L; van Buuren, T; Colesniuc, C; Monton, C; Valmianski, I; Schuller, Ivan K

2013-07-21

Phthalocyanines, a class of macrocyclic, square planar molecules, are extensively studied as semiconductor materials for chemical sensors, dye-sensitized solar cells, and other applications. In this study, we use angular dependent near-edge x-ray absorption fine structure (NEXAFS) spectroscopy as a quantitative probe of the orientation and electronic structure of H2-, Fe-, Co-, and Cu-phthalocyanine molecular thin films. NEXAFS measurements at both the carbon and nitrogen K-edges reveal that phthalocyanine films deposited on sapphire have upright molecular orientations, while films up to 50 nm thick deposited on gold substrates contain prostrate molecules. Although great similarity is observed in the carbon and nitrogen K-edge NEXAFS spectra recorded for the films composed of prostrate molecules, the H2-phthalocyanine exhibits the cleanest angular dependence due to its purely out-of-plane π* resonances at the absorption onset. In contrast, organometallic-phthalocyanine nitrogen K-edges have a small in-plane resonance superimposed on this π* region that is due to a transition into molecular orbitals interacting with the 3dx(2)-y(2) empty state. NEXAFS spectra recorded at the metal L-edges for the prostrate films reveal dramatic variations in the angular dependence of specific resonances for the Cu-phthalocyanines compared with the Fe-, and Co-phthalocyanines. The Cu L3,2 edge exhibits a strong in-plane resonance, attributed to its b1g empty state with dx(2)-y(2) character at the Cu center. Conversely, the Fe- and Co- phthalocyanine L3,2 edges have strong out-of-plane resonances; these are attributed to transitions into not only b1g (dz(2)) but also eg states with dxz and dyz character at the metal center.

Hearing the Transformation of Conical to Closed-Pipe Resonances

ERIC Educational Resources Information Center

Ruiz, Michael J.

2017-01-01

The harmonics for an open cone with slant length "L" are the same as the harmonics for an open pipe with length "L." When the cone is transformed through phases of closed-open conical frusta into a cylinder of length "L" closed at one end, the fundamental halves and only odd harmonics remain. A simple approach using…

Digital Affordances on WeChat: Learning Chinese as a Second Language

ERIC Educational Resources Information Center

Jin, Li

2018-01-01

Different from the traditional term language input, affordance, an ecological term, has been deployed to analyze the perceived opportunities for second language (L2) learning an environment provides to L2 learners. L2 learning occurs only when the semiotic resources in the environment resonate with the learner's capacities such as their abilities,…

A convenient method for determination of malathion based on the resonance Rayleigh scattering enhancement

NASA Astrophysics Data System (ADS)

Wu, Huan; Zhao, Yanmei; Tan, Xuanping; Huang, Yunmei; Yuan, Haiyan; Yang, Jidong

2017-09-01

A convenient method for determination of malathion (Mala) based on resonance Rayleigh scattering (RRS) enhancement of L-Tryptophan (L-Try)-Pd(II)-Mala system was proposed in this paper. The interaction between L-Try, Pd(II) and malathion in the system was investigated by fluorescence, RRS and UV-Vis absorption spectroscopy. In the optimum conditions, the RRS intensity of L-Try-Pd(II)-Mala system had a remarkable enhancement because the hydrolysis products of malathion would interact with Pd(II) and L-Try each other formed new complexes, which enhanced intensity was directly proportional to the malathion concentration within a certain range. Based on the RRS enhancement of L-Try-Pd(II) system by Mala, a novel, convenient and specific method for Mala determination was developed. To our knowledge, the method is the first RRS method for determination of Mala was reported. The detection limit for Mala was 6.7 ng/mL and the quantitative determination range was 0.06-0.6 μg/mL. The influence of coexisting substances on RRS was also investigated, and the RRS method exhibited good anti-interference ability. The new analytical method has been applied to determine of malathion in real samples with satisfactory results.

Resonant and Nonresonant Nonlinear Optical Spectroscopy of CDSE Quantum Dots for Nonlinear Photonic Applications

DTIC Science & Technology

2006-11-01

Temple D., Yoo K. P., Kim S. Y., Mott A., Namkung M., and Jung S. S., 2003: Large and pure refractive nonlinearity of nanostructure silica ... aerogel , Appl. Phys. Lett., 82(25), 4444-4446. [18] Sun W., Patton T., Stultz L., andClaude J. P., 2003: Resonant third-order nonlinearities of tetrakis

First-pass myocardial perfusion imaging with whole-heart coverage using L1-SPIRiT accelerated variable density spiral trajectories.

PubMed

Yang, Yang; Kramer, Christopher M; Shaw, Peter W; Meyer, Craig H; Salerno, Michael

2016-11-01

To design and evaluate two-dimensional (2D) L1-SPIRiT accelerated spiral pulse sequences for first-pass myocardial perfusion imaging with whole heart coverage capable of measuring eight slices at 2 mm in-plane resolution at heart rates up to 125 beats per minute (BPM). Combinations of five different spiral trajectories and four k-t sampling patterns were retrospectively simulated in 25 fully sampled datasets and reconstructed with L1-SPIRiT to determine the best combination of parameters. Two candidate sequences were prospectively evaluated in 34 human subjects to assess in vivo performance. A dual density broad transition spiral trajectory with either angularly uniform or golden angle in time k-t sampling pattern had the largest structural similarity and smallest root mean square error from the retrospective simulation, and the L1-SPIRiT reconstruction had well-preserved temporal dynamics. In vivo data demonstrated that both of the sampling patterns could produce high quality perfusion images with whole-heart coverage. First-pass myocardial perfusion imaging using accelerated spirals with optimized trajectory and k-t sampling pattern can produce high quality 2D perfusion images with whole-heart coverage at the heart rates up to 125 BPM. Magn Reson Med 76:1375-1387, 2016. © 2015 International Society for Magnetic Resonance in Medicine. © 2015 International Society for Magnetic Resonance in Medicine.

Quantitative detection of glucose level based on radiofrequency patch biosensor combined with volume-fixed structures.

PubMed

Qiang, Tian; Wang, Cong; Kim, Nam-Young

2017-12-15

A concept for characterizing a radiofrequency (RF) patch biosensor combined with volume-fixed structures is presented for timely monitoring of an individual's glucose levels based on frequency variation. Two types of patch biosensors-separately integrated with a backside slot (0.53μL) and a front-side tank (0.70μL) structure-were developed to achieve precise and efficient detection while excluding the effects of interference due to the liquidity, shape, and thickness of the tested glucose sample. A glucose test analyte at different concentrations (50-600mg/dL) was dropped into the volume-fixed structures. It fully interacted with the RF patch electromagnetic field, effectively and sensitively changing the resonance frequency and magnitude of the reflection coefficient. Measurement results based on the resonance frequency showed high sensitivity up to 1.13MHz and 1.97MHz per mg/dL, and low detection limits of 26.54mg/dL and 15.22mg/dL, for the two types of patch biosensors, respectively, as well as a short response time of less than 1s. Excellent reusability of the proposed biosensors was verified through three sets of measurements for each individual glucose sample. Regression analysis revealed a good linear correlation between glucose concentrations and the resonance frequency shift. Moreover, to facilitate a multi-parameter-sensitive detection of glucose, the magnitude of the reflection coefficient was also tested, and it showed a good linear correlation with the glucose concentration. Thus, the proposed approach can be adopted for distinguishing glucose solution levels, and it is a potential candidate for early-stage detection of glucose levels in diabetes patients. Copyright © 2017 Elsevier B.V. All rights reserved.

Magnetic resonance cell-tracking studies: spectrophotometry-based method for the quantification of cellular iron content after loading with superparamagnetic iron oxide nanoparticles.

PubMed

Böhm, Ingrid

2011-08-01

The purpose of this article is to present a user-friendly tool for quantifying the iron content of superparamagnetic labeled cells before cell tracking by magnetic resonance imaging (MRI). Iron quantification was evaluated by using Prussian blue staining and spectrophotometry. White blood cells were labeled with superparamagnetic iron oxide (SPIO) nanoparticles. Labeling was confirmed by light microscopy. Subsequently, the cells were embedded in a phantom and scanned on a 3 T magnetic resonance tomography (MRT) whole-body system. Mean peak wavelengths λ(peak) was determined at A(720 nm) (range 719-722 nm). Linearity was proven for the measuring range 0.5 to 10 μg Fe/mL (r  =  .9958; p  =  2.2 × 10(-12)). The limit of detection was 0.01 μg Fe/mL (0.1785 mM), and the limit of quantification was 0.04 μg Fe/mL (0.714 mM). Accuracy was demonstrated by comparison with atomic absorption spectrometry. Precision and robustness were also proven. On T(2)-weighted images, signal intensity varied according to the iron concentration of SPIO-labeled cells. Absorption spectrophotometry is both a highly sensitive and user-friendly technique that is feasible for quantifying the iron content of magnetically labeled cells. The presented data suggest that spectrophotometry is a promising tool for promoting the implementation of magnetic resonance-based cell tracking in routine clinical applications (from bench to bedside).

Detection of biomolecules in complex media using surface plasmon resonance sensors

NASA Astrophysics Data System (ADS)

Malone, Michael R.; Masson, Jean-Francois; Barhnart, Margaret; Beaudoin, Stephen; Booksh, Karl S.

2005-11-01

Detection of multiple biologically relevant molecules was accomplished at sub-ng/mL levels in highly fouling media using fiber- optic based surface plasmon resonance sensors. Myocardial infarction markers, myoglobin and cTnI, were quantified in full serum with limits of detection below 1 ng/mL. Biologically relevant levels are between 15-30 ng/mL and 1-5 ng/mL for myoglobin and cTnI respectively. Cytokines involved in chronic wound healing, Interleukin 1, Interleukin 6, and tumor necrosis factor α, were detected at around 1 ng/mL in cell culture media. Preliminary results in monitoring these cytokines in cell cultures expressing the cytokines were obtained. The protein diagnostic of spinal muscular atrophy, survival motor neuron protein, was quantified from cell lysate. To obtain such results in complex media, the sensor's stability to non-specific protein adsorption had to be optimized. A layer of the N-hydroxysuccinimide ester of 16-mercaptohexadecanoic acid is attached to the sensor. This layer optimizes the antibody attachment to the sensor while minimizing the non-specific signal from serum proteins.

Kinetic magnetic resonance imaging analysis of lumbar segmental mobility in patients without significant spondylosis.

PubMed

Tan, Yanlin; Aghdasi, Bayan G; Montgomery, Scott R; Inoue, Hirokazu; Lu, Chang; Wang, Jeffrey C

2012-12-01

The purpose of this study was to examine lumbar segmental mobility using kinetic magnetic resonance imaging (MRI) in patients with minimal lumbar spondylosis. Mid-sagittal images of patients who underwent weight-bearing, multi-position kinetic MRI for symptomatic low back pain or radiculopathy were reviewed. Only patients with a Pfirrmann grade of I or II, indicating minimal disc disease, in all lumbar discs from L1-2 to L5-S1 were included for further analysis. Translational and angular motion was measured at each motion segment. The mean translational motion of the lumbar spine at each level was 1.38 mm at L1-L2, 1.41 mm at L2-L3, 1.14 mm at L3-L4, 1.10 mm at L4-L5 and 1.01 mm at L5-S1. Translational motion at L1-L2 and L2-L3 was significantly greater than L3-4, L4-L5 and L5-S1 levels (P < 0.007). The mean angular motion at each level was 7.34° at L1-L2, 8.56° at L2-L3, 8.34° at L3-L4, 8.87° at L4-L5, and 5.87° at L5-S1. The L5-S1 segment had significantly less angular motion when compared to all other levels (P < 0.006). The mean percentage contribution of each level to the total angular mobility of the lumbar spine was highest at L2-L3 (22.45 %) and least at L5/S1 (14.71 %) (P < 0.001). In the current study, we evaluated lumbar segmental mobility in patients without significant degenerative disc disease and found that translational motion was greatest in the proximal lumbar levels whereas angular motion was similar in the mid-lumbar levels but decreased at L1-L2 and L5-S1.

Agrammatic Comprehension Caused by a Glioma in the Left Frontal Cortex

ERIC Educational Resources Information Center

Kinno, Ryuta; Muragaki, Yoshihiro; Hori, Tomokatsu; Maruyama, Takashi; Kawamura, Mitsuru; Sakai, Kuniyoshi L.

2009-01-01

It has been known that lesions in the left inferior frontal gyrus (L. IFG) do not always cause Broca's aphasia, casting doubt upon the specificity of this region. We have previously devised a picture-sentence matching task for a functional magnetic resonance imaging (fMRI) study, and observed that both pars triangularis (L. F3t) of L. IFG…

A molecularly imprinted polymer-coated CdTe quantum dot nanocomposite for tryptophan recognition based on the Förster resonance energy transfer process

NASA Astrophysics Data System (ADS)

Tirado-Guizar, Antonio; Paraguay-Delgado, Francisco; Pina-Luis, Georgina E.

2016-12-01

A new ‘turn-on’ Förster resonance energy transfer (FRET) nanosensor for l-tryptophan based on molecularly imprinted quantum dots (QDs) is proposed. The approach combines the advantages of the molecular imprinting technique, the fluorescent characteristics of the QDs and the energy transfer process. Silica-coated CdTe QDs were first synthesized and then molecularly imprinted using a sol-gel process without surfactants. The final composite presents stable fluorescence which increases with the addition of l-tryptophan. This ‘turn-on’ response is due to a FRET mechanism from the l-tryptophan as donor to the imprinted QD as acceptor. QDs are rarely applied as acceptors in FRET systems. The nanosensor shows selectivity towards l-tryptophan in the presence of other amino acids and interfering ions. The l-tryptophan nanosensor exhibits a linear range between 0 and 8 µM concentration, a detection limit of 350 nM and high selectivity. The proposed sensor was successfully applied for the detection of l-tryptophan in saliva. This novel sensor may offer an alternative approach to the design of a new generation of imprinted nanomaterials for the recognition of different analytes.

USSR Report, Cybernetics, Computers and Automation Technology.

DTIC Science & Technology

1987-03-02

Studies in the Area of EPR of Non- Ordered Solids, Spectral Recording, Processing and Analysis System (A.N. Bals, L.M. Kuzmina ; AVTOMETRIYA, No 2, Feb...L.M. Kuzmina , Riga] [Abstract] An automated system has been developed for electron paramagnetic resonance studies, oriented toward achievement of

An investigation on the interaction of DNA with hesperetin/apigenin in the presence of CTAB by resonance Rayleigh light scattering technique and its analytical application

NASA Astrophysics Data System (ADS)

Bi, Shuyun; Wang, Yu; Pang, Bo; Yan, Lili; Wang, Tianjiao

2012-05-01

Two new systems for measuring DNA at nanogram levels by a resonance Rayleigh light scattering (RLS) technique with a common spectrofluorometer were proposed. In the presence of cetyltrimethylammonium bromide (CTAB), the interaction of DNA with hesperetin and apigenin (two effective components of Chinese herbal medicine) could enhance RLS signals with the maximum peak at 363 and 433 nm respectively. The enhanced intensity of RLS was directly proportional to the concentration of DNA in the range of 0.022-4.4 μg mL-1 for DNA-CTAB-hesperetin system and 0.013-4.4 μg mL-1 for DNA-CTAB-apigenin system. The detection limit was 2.34 ng mL-1 and 2.97 ng mL-1 respectively. Synthetic samples were measured satisfactorily. The recovery of DNA-CTAB-hesperetin system was 97.3-101.9% and that of DNA-CTAB-apigenin system was 101.2-109.5%.

Global Observations of Magnetospheric High-m Poloidal Waves During the 22 June 2015 Magnetic Storm

NASA Technical Reports Server (NTRS)

Le, G.; Chi, P. J.; Strangeway, R. J.; Russell, C. T.; Slavin, J. A.; Takahashi, K.; Singer, H. J.; Anderson, B. J.; Bromund, K.; Fischer, D.;

Global observations of magnetospheric high-m poloidal waves during the 22 June 2015 magnetic storm.

PubMed

Le, G; Chi, P J; Strangeway, R J; Russell, C T; Slavin, J A; Takahashi, K; Singer, H J; Anderson, B J; Bromund, K; Fischer, D; Kepko, E L; Magnes, W; Nakamura, R; Plaschke, F; Torbert, R B

2017-04-28

We report global observations of high- m poloidal waves during the recovery phase of the 22 June 2015 magnetic storm from a constellation of widely spaced satellites of five missions including Magnetospheric Multiscale (MMS), Van Allen Probes, Time History of Events and Macroscale Interactions during Substorm (THEMIS), Cluster, and Geostationary Operational Environmental Satellites (GOES). The combined observations demonstrate the global spatial extent of storm time poloidal waves. MMS observations confirm high azimuthal wave numbers ( m  ~ 100). Mode identification indicates the waves are associated with the second harmonic of field line resonances. The wave frequencies exhibit a decreasing trend as L increases, distinguishing them from the single-frequency global poloidal modes normally observed during quiet times. Detailed examination of the instantaneous frequency reveals discrete spatial structures with step-like frequency changes along L . Each discrete L shell has a steady wave frequency and spans about 1  R E , suggesting that there exist a discrete number of drift-bounce resonance regions across L shells during storm times.

Rotation sensitivity analysis of a two-dimensional array of coupled resonators

NASA Astrophysics Data System (ADS)

Zamani Aghaie, Kiarash; Vigneron, Pierre-Baptiste; Digonnet, Michel J. F.

2015-03-01

In this paper, we study the rotation sensitivity of a gyroscope made of a two-dimensional array of coupled resonators consisting of N columns of one-dimensional coupled resonant optical waveguides (CROWs) connected by two bus waveguides, each CROW consisting of M identical ring resonators. We show that the maximum rotation sensitivity of this structure is a strong function of the parity of the number of rows M. For an odd number of rows, and when the number of columns is small, the maximum sensitivity is high, and it is slightly lower than the maximum sensitivity of a single-ring resonator with two input/output waveguides (the case M = N = 1), which is a resonant waveguide optical gyroscope (RWOG). For an even M and small N, the maximum sensitivity is much lower than that of the RWOG. Increasing the number columns N increases the sensitivity of an even-row 2D CROW sublinearly, as N0.39, up to 30 columns. In comparison, the maximum sensitivity of an RWOG of equal area increases faster, as √N. The sensitivity of the 2D CROW therefore always lags behind that of the RWOG. For a 2×2 CROW, if the spacing between the columns L is increased sufficiently the maximum sensitivity increases linearly with L due to the presence of a composite Mach- Zehnder interferometer in the structure. However, for equal footprints this sensitivity is also not larger than that of a single-ring resonator. Regardless of the number of rows and columns and the spacing, for the same footprint and propagation loss, a 2D CROW gyroscope is not more sensitive than an RWOG.

LHC vector resonance searches in the t\\overline{t}Z final state

NASA Astrophysics Data System (ADS)

Backović, Mihailo; Flacke, Thomas; Jain, Bithika; Lee, Seung J.

2017-03-01

LHC searches for BSM resonances in l + l - , jj, t\\overline{t} , γγ and VV final states have so far not resulted in discovery of new physics. Current results set lower limits on mass scales of new physics resonances well into the O(1) TeV range, assuming that the new resonance decays dominantly to a pair of Standard Model particles. While the SM pair searches are a vital probe of possible new physics, it is important to re-examine the scope of new physics scenarios probed with such final states. Scenarios where new resonances decay dominantly to final states other than SM pairs, even though well theoretically motivated, lie beyond the scope of SM pair searches. In this paper we argue that LHC searches for (vector) resonances beyond two particle final states would be useful complementary probes of new physics scenarios. As an example, we consider a class of composite Higgs models, and identify specific model parameter points where the color singlet, electrically neutral vector resonance ρ0 decays dominantly not to a pair of SM particles, but to a fermionic top partner T f1 and a top quark, with T f1 → tZ. We show that dominant decays of ρ 0 → T f1 t in the context of Composite Higgs models are possible even when the decay channel to a pair of T f1 is kinematically open. Our analysis deals with scenarios where both m ρ and {m}_T{{}{_f}}{_1} are of O(1) TeV, leading to highly boosted t\\overline{t}Z final state topologies. We show that the particular composite Higgs scenario we consider is discoverable at the LHC13 with as little as 30 fb-1, while being allowed by other existing experimental constraints.

Measurement of the Number of Light Neutrino Generations, Z Resonance Parameters, and Absolute Luminosity at the Aleph Detector

NASA Astrophysics Data System (ADS)

Wear, James A.

Measurements of the production cross section sigma (e^+e^-to Z to hadrons) have been made with the ALEPH detector in a seven-point energy scan across the Z resonance at the LEP e^+e^ - collider. The selection of hadronic Z decays is performed with a systematic uncertainty of 0.3%, resulting in 147,836 events. The absolute luminosity has been determined with a systematic uncertainty of 0.9%. These hadronic cross sections and ALEPH's measurement of Z decay into charged leptons, sigma(e^+e^ -to Z to l^+l^ -), are used in fits to extract parameters of the Z resonance in a model-independent way. The Z mass and total width are measured to be M_{Z } = 91.177 +/- 0.010 _{exp} +/- 0.020_{LEP} GeV and Gamma_{Z} = 2.482 +/- 0.018_{exp} +/- 0.006_{LEP } GeV where the second errors are due to LEP beam energy uncertainties. The Z decay partial widths are measured to be Gamma_{h} = 1.738 +/- 0.016 GeV, Gamma_{l} = 83.45 +/- 0.76 MeV, and Gamma_ {inv} = 0.493 +/- 0.015 GeV. The Born-level peak hadronic cross section is sigma_sp{had}{0 } = 41.58 +/- 0.44 nb, R = Gamma_{h }/Gamma_{l} = 20.83 +/- 0.21, and Gamma_{inv}/Gamma _{l} = 5.91 +/- 0.18. The number of light neutrino generations is determined to be N_{nu} = 2.96 +/- 0.09 and the Standard Model electroweak mixing angle to be sin^2 theta_{W} = 0.2325 +/- 0.0027.

Transfer of a weakly bound electron in collisions of Rydberg atoms with neutral particles. II. Ion-pair formation and resonant quenching of the Rb(nl) and Ne(nl) States by Ca, Sr, and Ba atoms

DOE Office of Scientific and Technical Information (OSTI.GOV)

Narits, A. A.; Mironchuk, E. S.; Lebedev, V. S., E-mail: vlebedev@sci.lebedev.ru

2013-10-15

Electron-transfer processes are studied in thermal collisions of Rydberg atoms with alkaline-earth Ca(4s{sup 2}), Sr(5s{sup 2}), and Ba(6s{sup 2}) atoms capable of forming negative ions with a weakly bound outermost p-electron. We consider the ion-pair formation and resonant quenching of highly excited atomic states caused by transitions between Rydberg covalent and ionic terms of a quasi-molecule produced in collisions of particles. The contributions of these reaction channels to the total depopulation cross section of Rydberg states of Rb(nl) and Ne(nl) atoms as functions of the principal quantum number n are compared for selectively excited nl-levels with l Much-Less-Than n andmore » for states with large orbital quantum numbers l = n - 1, n - 2. It is shown that the contribution from resonant quenching dominates at small values of n, and the ion-pair formation process begins to dominate with increasing n. The values and positions of the maxima of cross sections for both processes strongly depend on the electron affinity of an alkaline-earth atom and on the orbital angular momentum l of a highly excited atom. It is shown that in the case of Rydberg atoms in states with large l {approx} n - 1, the rate constants of ion-pair formation and collisional quenching are considerably lower than those for nl-levels with l Much-Less-Than n.« less

Search for narrow-width tt(bar) resonances in pp(bar) collisons at sqrt(s)=1.8TeV

NASA Astrophysics Data System (ADS)

Jain, Supriya

2004-03-01

We present a preliminary result on a search for narrow-width resonances that decay into ttbar pairs using 130 pb^{-1} of lepton plus jets data in ppbar collisions at center of mass energy = 1.8 TeV. No significant deviation from Standard Model prediction is observed. 95% C.L. upper limits on the production cross section of the narrow-width resonance times its branching fraction to ttbar are presented for different resonance masses, M_X. We also exclude the existence of a leptophobic topcolor particle, X, with M_X < 560 GeV/c^2 for a width \\Gamma_X = 0.012 M_X.

Transformer induced instability of the series resonant converter

NASA Technical Reports Server (NTRS)

King, R. J.; Stuart, T. A.

1983-01-01

It is shown that the common series resonant power converter is subject to a low frequency oscillation that can lead to the loss of cyclic stability. This oscillation is caused by a low frequency resonant circuit formed by the normal L and C components in series with the magnetizing inductance of the output transformer. Three methods for eliminating this oscillation are presented and analyzed. One of these methods requires a change in the circuit topology during the resonance cycle. This requires a new set of steady state equations which are derived and presented in a normalized form. Experimental results are included which demonstrate the nature of the low frequency oscillation before cyclic stability is lost.

Geophysical variables and behavior: XC. What people consider strange: change in proportions of reports of Fortean phenomena over time.

PubMed

Persinger, M A

2001-02-01

The proportions of 3,667 reports classified as unusual or odd events within eight major categories for four contiguous blocks of time between 1770 and 1970 were compared for disconcordance. The major source of the disconcordance (phi = .52) of reports between the major categories and time was due to the decrease in the numbers of reports of falls of ice, rocks, and animals but increased numbers of reports of odd luminosities, labelled as unidentified flying objects, after the mid 1930s. One hypothesis to explain this result is that cultural changes in attributions for causes of natural phenomena may affect their designation as strange rather than mundane.

Geologic setting of the John Day Country, Grant County, Oregon

USGS Publications Warehouse

Thayer, Thomas P.

1977-01-01

One of the Pacific Northwest's most notable outdoor recreation areas, the "John Day Country" in northeastern Oregon, is named after a native Virginian who was a member of the Astor expedition to the mouth of the Columbia River in 1812. There is little factual information about John Day except that he was born in Culpeper County, Virginia, about 1770. It is known also that in 1810 this tall pioneer "with an elastic step as if he trod on springs" joined John Jacob Astor's overland expedition under Wilson Price Hunt to establish a vast fur-gathering network in the Western States based on a major trading post at the mouth of the Columbia River.

Resonance behavior of atomic and molecular photoionization amplitudes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cherepkov, N. A.; Kuznetsov, V. V.; Semenov, S. K.

The behavior of the partial photoionization amplitudes with a given orbital angular momentum l in the complex plane in resonances is studied. In the autoionization resonances the trajectory of the amplitude in the complex plane corresponds to a circle. With increasing photoelectron energy the amplitude moves about a circle in the counterclockwise direction. The new expressions for the partial amplitudes in the resonance are proposed which are similar to the Fano form but contain the 'partial' profile parameters which are connected with the Fano parameter q by a simple relation. In the giant dipole resonances the amplitudes in the complexmore » plane also move about a circle in the counterclockwise direction provided the Coulomb phase is excluded from the amplitude. In the correlational resonances created by channel interactions with the giant dipole resonance the trajectories of the amplitudes acquire a loop about which the amplitudes move in the counterclockwise direction. Very similar behavior of partial photoionization amplitudes in the complex plane is demonstrated also for the dipole transitions from the K shells of the N{sub 2} molecule in the {sigma}* shape resonance.« less

Development of Novel Piezoelectric Biosensor Using PZT Ceramic Resonator for Detection of Cancer Markers.

PubMed

Su, Li; Fong, Chi-Chun; Cheung, Pik-Yuan; Yang, Mengsu

2017-01-01

A novel biosensor based on piezoelectric ceramic resonator was developed for direct detection of cancer markers in the study. For the first time, a commercially available PZT ceramic resonator with high resonance frequency was utilized as transducer for a piezoelectric biosensor. A dual ceramic resonators scheme was designed wherein two ceramic resonators were connected in parallel: one resonator was used as the sensing unit and the other as the control unit. This arrangement minimizes environmental influences including temperature fluctuation, while achieving the required frequency stability for biosensing applications. The detection of the cancer markers Prostate Specific Antigen (PSA) and α-Fetoprotein (AFP) was carried out through frequency change measurement. The device showed high sensitivity (0.25 ng/ml) and fast detection (within 30 min) with small samples (1 μl), which is compatible with the requirements of clinical measurements. The results also showed that the ceramic resonator-based piezoelectric biosensor platform could be utilized with different chemical interfaces, and had the potential to be further developed into biosensor arrays with different specificities for simultaneous detection of multiple analytes.

Simulating the Resonant Acoustic Mixer

DTIC Science & Technology

2013-08-02

uuu T Lu tTtxLx (19) where L, T, L/T and 0 are the length, time, velocity and density scales for the problem...kjikjikjikjikjikji kji kji n kji n kji ffffff V t UUU (46) The half-index notation used in (45) and (46) allows flexibility in

Plasmonic nanorod arrays of a two-segment dimer and a coaxial cable with 1 nm gap for large field confinement and enhancement

NASA Astrophysics Data System (ADS)

Cheng, Zi-Qiang; Nan, Fan; Yang, Da-Jie; Zhong, Yu-Ting; Ma, Liang; Hao, Zhong-Hua; Zhou, Li; Wang, Qu-Quan

2015-01-01

Seeking plasmonic nanostructures with large field confinement and enhancement is significant for photonic and electronic nanodevices with high sensitivity, reproducibility, and tunability. Here, we report the synthesis of plasmonic arrays composed of two-segment dimer nanorods and coaxial cable nanorods with ~1 nm gap insulated by a self-assembled Raman molecule monolayer. The gap-induced plasmon coupling generates an intense field in the gap region of the dimer junction and the cable interlayer. As a result, the longitudinal plasmon resonance of nanorod arrays with high tunability is obviously enhanced. Most interestingly, the field enhancement of dimer nanorod arrays can be tuned by the length ratio L1/L2 of the two segments, and the maximal enhancement appears at L1/L2 = 1. In that case, the two-photon luminescence (TPL) of dimer nanorod arrays and the Raman intensity in the dimer junction is enhanced by 27 and 30 times, respectively, under resonant excitation. In the same way, the Raman intensity in the gap region is enhanced 16 times for the coaxial cable nanorod arrays. The plasmonic nanorod arrays synthesized by the facile method, having tunable plasmon properties and large field enhancement, indicate an attractive pathway to the photonic nanodevices.Seeking plasmonic nanostructures with large field confinement and enhancement is significant for photonic and electronic nanodevices with high sensitivity, reproducibility, and tunability. Here, we report the synthesis of plasmonic arrays composed of two-segment dimer nanorods and coaxial cable nanorods with ~1 nm gap insulated by a self-assembled Raman molecule monolayer. The gap-induced plasmon coupling generates an intense field in the gap region of the dimer junction and the cable interlayer. As a result, the longitudinal plasmon resonance of nanorod arrays with high tunability is obviously enhanced. Most interestingly, the field enhancement of dimer nanorod arrays can be tuned by the length ratio L1/L2 of the two segments, and the maximal enhancement appears at L1/L2 = 1. In that case, the two-photon luminescence (TPL) of dimer nanorod arrays and the Raman intensity in the dimer junction is enhanced by 27 and 30 times, respectively, under resonant excitation. In the same way, the Raman intensity in the gap region is enhanced 16 times for the coaxial cable nanorod arrays. The plasmonic nanorod arrays synthesized by the facile method, having tunable plasmon properties and large field enhancement, indicate an attractive pathway to the photonic nanodevices. Electronic supplementary information (ESI) available. See DOI: 10.1039/c4nr05544f

Levels of essential and non-essential metals in ginger (Zingiber officinale) cultivated in Ethiopia.

PubMed

Wagesho, Yohannes; Chandravanshi, Bhagwan Singh

2015-01-01

Ginger (Zingiber officinale Roscoe) is a common condiment for various foods and beverages and widely used worldwide as a spice. Its extracts are used extensively in the food, beverage, and confectionary industries in the production of products such as marmalade, pickles, chutney, ginger beer, ginger wine, liquors, biscuits, and other bakery products. In Ethiopia, it is among the important spices used in every kitchen to flavor stew, tea, bread and local alcoholic drinks. It is also chiefly used medicinally for indigestion, stomachache, malaria, fevers, common cold, and motion sickness. The literature survey revealed that there is no study conducted on the determination of metals in ginger cultivated in Ethiopia. Hence it is worthwhile to determine the levels of essential and non-essential metals in ginger cultivated in Ethiopia. The levels of essential (Ca, Mg, Fe, Zn, Cu, Co, Cr, Mn, and Ni) and non-essential (Cd and Pb) metals in ginger (Zingiber officinale Roscoe) cultivated in four different regions of Ethiopia and the soil where it was grown were determined by flame atomic absorption spectrometry. 0.5 g of oven dried ginger and soil samples were digested using 3 mL of HNO3 and 1 mL of HClO4 at 210°C for 3 h and a mixture of 6 mL aqua-regia and 1.5 mL H2O2 at 270°C for 3 h, respectively. The mean metal concentration (μg/g dry weight basis) ranged in the ginger and soil samples, respectively, were: Ca (2000-2540, 1770-3580), Mg (2700-4090, 1460-2440), Fe (41.8-89.0, 21700-46900), Zn (38.5-55.2, 255-412), Cu (1.1-4.8, 3.80-33.9), Co (2.0-7.6, 48.5-159), Cr (6.0-10.8, 110-163), Mn (184-401, 1760-6470), Ni (5.6-8.4, 14.1-79.3) and Cd (0.38-0.97, 0.24-1.1). The toxic metal Pb was not detected in both the ginger and soil samples. There was good correlation between some metals in ginger and soil samples while poor correlation between other metals (Fe, Ni, Cu). This study revealed that Ethiopian gingers are good source of essential metals and free from toxic metal Pb while containing negligible amount of Cd.

Value of three-dimensional speckle tracking echocardiography to assess left ventricular function in hyperuricemia patients.

PubMed

Zhang, Xiaojie; Lu, Qing; Zhang, Zhuojun; Chen, Yongle; Wang, Yanan; Wang, Youngshi; Li, Zheng; Jiang, Lindi

2018-05-22

To assess the value of three-dimensional speckle tracking echocardiography (3D STE) in evaluating the left ventricular (LV) function in hyperuricemia patients. We enrolled 15 healthy controls and 40 hyperuricemia patients and collected and analyzed full-volume 3D STE images of the left ventricle in the apical four-chamber heart view. Laboratory tests and 3D STE parameters, including left ventricular ejection fraction, left ventricular end-diastolic volume, left ventricular end-systolic volume, stroke volume (SV), global longitudinal strain (GLS), and global circumferential strain (GCS), were compared between hyperuricemia patients and healthy controls. Hyperuricemia patients exhibited higher body mass index (24.70 ± 2.9 vs. 21.83 ± 2.4 kg/m 2 , p = 0.001), C-reactive protein (5.82 ± 9.4 vs. 1.12 ± 1.8 g/L, p = 0.012), alanine transaminase (34.26 ± 26.6 vs. 17.60 ± 13.0 U/L, p = 0.011), aspartate transaminase (24.90 ± 11.3 vs. 17.70 ± 4.1 U/L, p = 0.001), blood urea nitrogen (5.11 ± 1.6 vs. 4.18 ± 0.6 mmol/L, p = 0.046), and serum creatinine (90.25 ± 14.6 vs. 77.93 ± 10.8 μmol/L, p = 0.006) levels, as well as a lower estimated glomerular filtration rate (87.87 ± 16.5 vs. 103.64 ± 11.3 mL/min/1.73m 2 , p = 0.002). The 3D STE parameters reflecting LV function, including SV (54.71 ± 9.6 vs. 61.92 ± 14.4 mL, p = 0.024), GLS (- 20.51 ± 4.0 vs. - 23.20 ± 4.0%, p = 0.019), and GCS (- 31.30 ± 5.0 vs. - 35.65 ± 2.5%, p = 0.000), were significantly decreased in hyperuricemia patients. Furthermore, GCS was significantly correlated with the serum uric acid (sUA) level even after adjustment of confounding variables like age, body mass index, and serum creatinine. 3D STE is a novel technique for recognizing the early decline in LV function, with GLS and GCS serving as reliable indicators, in hyperuricemia patients. Moreover, the degree of decline in LV function may be correlated with the sUA level in hyperuricemia patients.

Delocalization and occupancy effects of 5f orbitals in plutonium intermetallics using L3-edge resonant X-ray emission spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Booth, C. H.; Medling, S. A.; Jiang, Yu

2014-06-24

Although actinide (An) L3 -edge X-ray absorption near-edge structure (XANES) spectroscopy has been very effective in determining An oxidation states in insulating, ionically bonded materials, such as in certain coordination compounds and mineral systems, the technique fails in systems featuring more delocalized 5f orbitals, especially in metals. Recently, actinide L3-edge resonant X-ray emission spec- troscopy (RXES) has been shown to be an effective alternative. This technique is further demonstrated here using a parameterized partial unoccupied density of states method to quantify both occupancy and delocalization of the 5f orbital in ?-Pu, ?-Pu, PuCoGa5 , PuCoIn5 , and PuSb2. These newmore » results, supported by FEFF calculations, highlight the effects of strong correlations on RXES spectra and the technique?s ability to differentiate between f-orbital occupation and delocalization.« less

Lumbar vertebral hemangioma with extradural extension, causing neurogenic claudication: a case report.

PubMed

Jouibari, Morteza Faghih; Khoshnevisan, Alireza; Ghodsi, Seyed Mohammad; Nejat, Farideh; Naderi, Soheil; Abdollahzadeh, Sina

2011-01-01

The authors present a rare case of lumbar vertebral hemangioma extending to the epidural space with a bisected appearance and impinging on thecal sac. This 52-year-old lady presented with one year history of low back pain and bilateral leg radiation. Plain radiography showed vertical linear streaks at L2 vertebral body and axial computed tomography (CT) scan revealed small "polka dot" appearance within the vertebral body. Magnetic resonance imaging (MRI) showed low signal intensity on T1-weighted images in L2 vertebral body which was not characteristic for hemangioma. The patient underwent an L2 laminectomy, spinal canal decompression and posterior spinal instrumentation. This study indicates that lumbar vertebral hemangioma can extend to the epidural space and cause neurologic symptoms. Magnetic resonance imaging may not show diagnostic features, especially in active lesions and plain radiography and CT scan may be helpful.

Multilingual Processing in the Brain

ERIC Educational Resources Information Center

van den Noort, Maurits; Struys, Esli; Kim, Kayoung; Bosch, Peggy; Mondt, Katrien; van Kralingen, Rosalinde; Lee, Mikyoung; van de Craen, Piet

2014-01-01

In this paper, in contrast to previous neuroimaging literature reviews on first language (L1) and second language (L2), the focus was only on neuroimaging studies that were directly conducted on multilingual participants. In total, 14 neuroimaging studies were included in our study such as 10 functional magnetic resonance imaging, 1 positron…

Growing up Radical: Investigation of Benzyl-Like Radicals with Increasing Chain Lengths

NASA Astrophysics Data System (ADS)

Korn, Joseph A.; Jawad, Khadija M.; Hewett, Daniel M.; Zwier, Timothy S.

2015-06-01

Combustion processes involve complex chemistry including pathways leading to polyaromatic hydrocarbons (PAHs) from small molecule precursors. Resonance stabilized radicals (RSRs) likely play an important role in the pathways to PAHs due to their unusual stability. Benzyl radical is a prototypical RSR that is stabilized by conjugation with the phenyl ring. Earlier work on α-methyl benzyl radical showed perturbations to the spectroscopy due to a hindered methyl rotor. If the alkyl chain is lengthened then multiple conformations become possible. This talk will discuss the jet-cooled spectroscopy of α-ethyl benzyl radical and α-propyl benzyl radical produced from the discharge of 1-phenyl propanol and 1-phenyl butanol respectively. Electronic spectra were obtained via resonant two-photon ionization, and IR spectra were obtained by resonant ion-dip infrared spectroscopy. Kidwell, N. M.; Reilly, N. J.; Nebgen, B.; Mehta-Hurt, D. N.; Hoehn, R. D.; Kokkin, D. L.; McCarthy, M. C.; Slipchenko, L. V.; Zwier, T. S. The Journal of Physical Chemistry A 2013, 117, 13465.

Improved L-C resonant decay technique for Q measurement of quasilinear power inductors: New results for MPP and ferrite powdered cores

NASA Technical Reports Server (NTRS)

Niedra, Janis M.; Gerber, Scott S.

1995-01-01

The L-C resonant decay technique for measuring circuit Q or losses is improved by eliminating the switch from the inductor-capacitor loop. A MOSFET switch is used instead to momentarily connect the resonant circuit to an existing voltage source, which itself is gated off during the decay transient. Very reproducible, low duty cycle data could be taken this way over a dynamic voltage range of at least 10:1. Circuit Q is computed from a polynomial fit to the sequence of the decaying voltage maxima. This method was applied to measure the losses at 60 kHz in inductors having loose powder cores of moly permalloy and an Mn-Zn power ferrite. After the copper and capacitor losses are separated out, the resulting specific core loss is shown to be roughly as expected for the MPP powder, but anomalously high for the ferrite powder. Possible causes are mentioned.

Search for the production of narrow tb[over] resonances in 1.9 fb;{-1} of pp[over] collisions at sqrt[s] = 1.96 TeV.

PubMed

Aaltonen, T; Adelman, J; Akimoto, T; Alvarez González, B; Amerio, S; Amidei, D; Anastassov, A; Annovi, A; Antos, J; Apollinari, G; Apresyan, A; Arisawa, T; Artikov, A; Ashmanskas, W; Attal, A; Aurisano, A; Azfar, F; Badgett, W; Barbaro-Galtieri, A; Barnes, V E; Barnett, B A; Barria, P; Bartos, P; Bartsch, V; Bauer, G; Beauchemin, P-H; Bedeschi, F; Beecher, D; Behari, S; Bellettini, G; Bellinger, J; Benjamin, D; Beretvas, A; Beringer, J; Bhatti, A; Binkley, M; Bisello, D; Bizjak, I; Blair, R E; Blocker, C; Blumenfeld, B; Bocci, A; Bodek, A; Boisvert, V; Bolla, G; Bortoletto, D; Boudreau, J; Boveia, A; Brau, B; Bridgeman, A; Brigliadori, L; Bromberg, C; Brubaker, E; Budagov, J; Budd, H S; Budd, S; Burke, S; Burkett, K; Busetto, G; Bussey, P; Buzatu, A; Byrum, K L; Cabrera, S; Calancha, C; Campanelli, M; Campbell, M; Canelli, F; Canepa, A; Carls, B; Carlsmith, D; Carosi, R; Carrillo, S; Carron, S; Casal, B; Casarsa, M; Castro, A; Catastini, P; Cauz, D; Cavaliere, V; Cavalli-Sforza, M; Cerri, A; Cerrito, L; Chang, S H; Chen, Y C; Chertok, M; Chiarelli, G; Chlachidze, G; Chlebana, F; Cho, K; Chokheli, D; Chou, J P; Choudalakis, G; Chuang, S H; Chung, K; Chung, W H; Chung, Y S; Chwalek, T; Ciobanu, C I; Ciocci, M A; Clark, A; Clark, D; Compostella, G; Convery, M E; Conway, J; Cordelli, M; Cortiana, G; Cox, C A; Cox, D J; Crescioli, F; Cuenca Almenar, C; Cuevas, J; Culbertson, R; Cully, J C; Dagenhart, D; Datta, M; Davies, T; de Barbaro, P; De Cecco, S; Deisher, A; De Lorenzo, G; Dell'orso, M; Deluca, C; Demortier, L; Deng, J; Deninno, M; Derwent, P F; Di Canto, A; di Giovanni, G P; Dionisi, C; Di Ruzza, B; Dittmann, J R; D'Onofrio, M; Donati, S; Dong, P; Donini, J; Dorigo, T; Dube, S; Efron, J; Elagin, A; Erbacher, R; Errede, D; Errede, S; Eusebi, R; Fang, H C; Farrington, S; Fedorko, W T; Feild, R G; Feindt, M; Fernandez, J P; Ferrazza, C; Field, R; Flanagan, G; Forrest, R; Frank, M J; Franklin, M; Freeman, J C; Furic, I; Gallinaro, M; Galyardt, J; Garberson, F; Garcia, J E; Garfinkel, A F; Garosi, P; Genser, K; Gerberich, H; Gerdes, D; Gessler, A; Giagu, S; Giakoumopoulou, V; Giannetti, P; Gibson, K; Gimmell, J L; Ginsburg, C M; Giokaris, N; Giordani, M; Giromini, P; Giunta, M; Giurgiu, G; Glagolev, V; Glenzinski, D; Gold, M; Goldschmidt, N; Golossanov, A; Gomez, G; Gomez-Ceballos, G; Goncharov, M; González, O; Gorelov, I; Goshaw, A T; Goulianos, K; Gresele, A; Grinstein, S; Grosso-Pilcher, C; Grundler, U; Guimaraes da Costa, J; Gunay-Unalan, Z; Haber, C; Hahn, K; Hahn, S R; Halkiadakis, E; Han, B-Y; Han, J Y; Happacher, F; Hara, K; Hare, D; Hare, M; Harper, S; Harr, R F; Harris, R M; Hartz, M; Hatakeyama, K; Hays, C; Heck, M; Heijboer, A; Heinrich, J; Henderson, C; Herndon, M; Heuser, J; Hewamanage, S; Hidas, D; Hill, C S; Hirschbuehl, D; Hocker, A; Hou, S; Houlden, M; Hsu, S-C; Huffman, B T; Hughes, R E; Husemann, U; Hussein, M; Huston, J; Incandela, J; Introzzi, G; Iori, M; Ivanov, A; James, E; Jang, D; Jayatilaka, B; Jeon, E J; Jha, M K; Jindariani, S; Johnson, W; Jones, M; Joo, K K; Jun, S Y; Jung, J E; Junk, T R; Kamon, T; Kar, D; Karchin, P E; Kato, Y; Kephart, R; Ketchum, W; Keung, J; Khotilovich, V; Kilminster, B; Kim, D H; Kim, H S; Kim, H W; Kim, J E; Kim, M J; Kim, S B; Kim, S H; Kim, Y K; Kimura, N; Kirsch, L; Klimenko, S; Knuteson, B; Ko, B R; Kondo, K; Kong, D J; Konigsberg, J; Korytov, A; Kotwal, A V; Kreps, M; Kroll, J; Krop, D; Krumnack, N; Kruse, M; Krutelyov, V; Kubo, T; Kuhr, T; Kulkarni, N P; Kurata, M; Kwang, S; Laasanen, A T; Lami, S; Lammel, S; Lancaster, M; Lander, R L; Lannon, K; Lath, A; Latino, G; Lazzizzera, I; Lecompte, T; Lee, E; Lee, H S; Lee, S W; Leone, S; Lewis, J D; Lin, C-S; Linacre, J; Lindgren, M; Lipeles, E; Lister, A; Litvintsev, D O; Liu, C; Liu, T; Lockyer, N S; Loginov, A; Loreti, M; Lovas, L; Lucchesi, D; Luci, C; Lueck, J; Lujan, P; Lukens, P; Lungu, G; Lyons, L; Lys, J; Lysak, R; Macqueen, D; Madrak, R; Maeshima, K; Makhoul, K; Maki, T; Maksimovic, P; Malde, S; Malik, S; Manca, G; Manousakis-Katsikakis, A; Margaroli, F; Marino, C; Marino, C P; Martin, A; Martin, V; Martínez, M; Martínez-Ballarín, R; Maruyama, T; Mastrandrea, P; Masubuchi, T; Mathis, M; Mattson, M E; Mazzanti, P; McFarland, K S; McIntyre, P; McNulty, R; Mehta, A; Mehtala, P; Menzione, A; Merkel, P; Mesropian, C; Miao, T; Miladinovic, N; Miller, R; Mills, C; Milnik, M; Mitra, A; Mitselmakher, G; Miyake, H; Moggi, N; Mondragon, M N; Moon, C S; Moore, R; Morello, M J; Morlock, J; Movilla Fernandez, P; Mülmenstädt, J; Mukherjee, A; Muller, Th; Mumford, R; Murat, P; Mussini, M; Nachtman, J; Nagai, Y; Nagano, A; Naganoma, J; Nakamura, K; Nakano, I; Napier, A; Necula, V; Nett, J; Neu, C; Neubauer, M S; Neubauer, S; Nielsen, J; Nodulman, L; Norman, M; Norniella, O; Nurse, E; Oakes, L; Oh, S H; Oh, Y D; Oksuzian, I; Okusawa, T; Orava, R; Osterberg, K; Pagan Griso, S; Pagliarone, C; Palencia, E; Papadimitriou, V; Papaikonomou, A; Paramonov, A A; Parks, B; Pashapour, S; Patrick, J; Pauletta, G; Paulini, M; Paus, C; Peiffer, T; Pellett, D E; Penzo, A; Phillips, T J; Piacentino, G; Pianori, E; Pinera, L; Pitts, K; Plager, C; Pondrom, L; Poukhov, O; Pounder, N; Prakoshyn, F; Pronko, A; Proudfoot, J; Ptohos, F; Pueschel, E; Punzi, G; Pursley, J; Rademacker, J; Rahaman, A; Ramakrishnan, V; Ranjan, N; Redondo, I; Renton, P; Renz, M; Rescigno, M; Richter, S; Rimondi, F; Ristori, L; Robson, A; Rodrigo, T; Rodriguez, T; Rogers, E; Rolli, S; Roser, R; Rossi, M; Rossin, R; Roy, P; Ruiz, A; Russ, J; Rusu, V; Rutherford, B; Saarikko, H; Safonov, A; Sakumoto, W K; Saltó, O; Santi, L; Sarkar, S; Sartori, L; Sato, K; Savoy-Navarro, A; Schlabach, P; Schmidt, A; Schmidt, E E; Schmidt, M A; Schmidt, M P; Schmitt, M; Schwarz, T; Scodellaro, L; Scribano, A; Scuri, F; Sedov, A; Seidel, S; Seiya, Y; Semenov, A; Sexton-Kennedy, L; Sforza, F; Sfyrla, A; Shalhout, S Z; Shears, T; Shepard, P F; Shimojima, M; Shiraishi, S; Shochet, M; Shon, Y; Shreyber, I; Sinervo, P; Sisakyan, A; Slaughter, A J; Slaunwhite, J; Sliwa, K; Smith, J R; Snider, F D; Snihur, R; Soha, A; Somalwar, S; Sorin, V; Spreitzer, T; Squillacioti, P; Stanitzki, M; St Denis, R; Stelzer, B; Stelzer-Chilton, O; Stentz, D; Strologas, J; Strycker, G L; Suh, J S; Sukhanov, A; Suslov, I; Suzuki, T; Taffard, A; Takashima, R; Takeuchi, Y; Tanaka, R; Tecchio, M; Teng, P K; Terashi, K; Thom, J; Thompson, A S; Thompson, G A; Thomson, E; Tipton, P; Ttito-Guzmán, P; Tkaczyk, S; Toback, D; Tokar, S; Tollefson, K; Tomura, T; Tonelli, D; Torre, S; Torretta, D; Totaro, P; Tourneur, S; Trovato, M; Tsai, S-Y; Tu, Y; Turini, N; Ukegawa, F; Vallecorsa, S; van Remortel, N; Varganov, A; Vataga, E; Vázquez, F; Velev, G; Vellidis, C; Vidal, M; Vidal, R; Vila, I; Vilar, R; Vine, T; Vogel, M; Volobouev, I; Volpi, G; Wagner, P; Wagner, R G; Wagner, R L; Wagner, W; Wagner-Kuhr, J; Wakisaka, T; Wallny, R; Wang, S M; Warburton, A; Waters, D; Weinberger, M; Weinelt, J; Wester, W C; Whitehouse, B; Whiteson, D; Wicklund, A B; Wicklund, E; Wilbur, S; Williams, G; Williams, H H; Wilson, P; Winer, B L; Wittich, P; Wolbers, S; Wolfe, C; Wright, T; Wu, X; Würthwein, F; Xie, S; Yagil, A; Yamamoto, K; Yamaoka, J; Yang, U K; Yang, Y C; Yao, W M; Yeh, G P; Yi, K; Yoh, J; Yorita, K; Yoshida, T; Yu, G B; Yu, I; Yu, S S; Yun, J C; Zanello, L; Zanetti, A; Zhang, X; Zheng, Y; Zucchelli, S

2009-07-24

We present new limits on resonant tb[over] production in pp[over] collisions at sqrt[s] = 1.96 TeV, using 1.9 fb;{-1} of data recorded with the CDF II detector at the Fermilab Tevatron. We reconstruct a candidate tb[over] mass in events with a lepton, neutrino candidate, and two or three jets, and search for anomalous tb[over] production as modeled by W;{'} --> tb[over]. We set a new limit on a right-handed W;{'} with standard model-like coupling, excluding any mass below 800 GeV/c;{2} at 95% C.L. The cross section for any narrow, resonant tb[over] production between 750 and 950 GeV/c;{2} is found to be less than 0.28 pb at 95% C.L. We also present an exclusion of the W;{'} coupling strength versus W;{'} mass over the range 300-950 GeV/c;{2}.

Definitive determination of the transverse Hamiltonian parameters in the single molecule magnet Mn_12-Ac

NASA Astrophysics Data System (ADS)

Edwards, Rachel S.; Hill, Stephen; North, J. Micah; Dalal, Naresh; Jones, Shaela; Maccagnano, Sara

2003-03-01

We present high frequency high field electron paramagnetic resonance (EPR) measurements on the single molecule magnet Mn_12-Ac. Using a split coil magnet and highly sensitive resonant cavity techniques we are able to perform an angle dependent study of the single crystal EPR with the field applied in the hard plane, and hence unambiguously determine the transverse Hamiltonian parameters to fourth order. A variation in the line-shape of the resonances with angle supports the recent proposal of a ligand disorder in this material causing local quadratic anisotropy, and is used to determine the magnitude of the second order transverse term. This could have important implications for describing magnetic quantum tunneling in Mn_12-Ac. S. Hill, J.A.A.J. Perenboom, N.S. Dalal, T. Hathaway, T. Stalcup and J.S. Brooks, Phys. Rev. Lett. 80, 2453 (1998). A. Cornia, R. Sessoli, L. Sorace, D. Gatteschi, A.L. Barra and C. Daiguebonne, cond-mat/0112112.

Evidence for Exotic Meson Production in π -p Interactions at 18 GeV/c

NASA Astrophysics Data System (ADS)

Willutzki, H. J.

2000-10-01

The η π - system has been studied in the reaction π -p → η π -p at 18 GeV/c. A large asymmetry in the angular distribution is observed indicating interference between L-even and L-odd partial waves. The data require interference between the a2(1320) and an exotic JPC=1-+ resonance π 1(1400) with M=(1370 ± 16+50-30) MeV/c2 and Γ =(385 ± 40+65-105) MeV/c2. A second exotic JPC=1-+ resonance π 1(1600) has been found in the reaction π -p → π +π -π -p in the ρ π channel. A mass-dependent fit yields M=(1593 ± 8+29-47) MeV/c2 and Γ =(168 ± 20+150-12) MeV/c2. Presumably the same resonance is also found in the η '(959)π - final state with M=(1589 ± 9) MeV/c2 and Γ =(380 ± 22) MeV/c2.

Fingerprinting analysis of Rhizoma chuanxiong of commercial types using 1H nuclear magnetic resonance spectroscopy and high performance liquid chromatography method.

PubMed

Qin, Hai-Lin; Deng, An-Jun; Du, Guan-Hua; Wang, Peng; Zhang, Jin-Lan; Li, Zhi-Hong

2009-06-01

The (1)H nuclear magnetic resonance ((1)H NMR) fingerprints of fractionated non-polar extracts (control substance for a plant drug (CSPD) A) from Rhizoma chuanxiong, the rhizomes of Ligusticum chuanxiong Hort., of seven specimens from different sources were measured on Fourier Transform (FT)-NMR spectrometer and assigned by comparing them with the (1)H NMR spectra of the isolated pure compounds. The (1)H NMR fingerprints showed exclusively characteristic resonance signals of the major special constituents of the plant. Although the differences in the relative intensity of the (1)H NMR signals due to a discrepancy in the ratio of the major constituents among these samples could be confirmed by high performance liquid chromatography analysis, the general features of the (1)H NMR fingerprint established for an authentic sample of the rhizomes of L. chuanxiong exhibited exclusive data from those special compounds and can be used for authenticating L. Chuanxiong species.

Numerical modelling of new rockfall interception nets

NASA Astrophysics Data System (ADS)

von Boetticher, Albrecht; Volkwein, Axel; Wendeler, Corinna

2010-05-01

The design and certification of effective rockfall protection barriers is mainly achieved through 1:1 prototype testing. In order to reduce development costs of a prototype it is recommended that pre-studies using numerical simulations are performed. A large component to modelling rockfall protection systems is the numerical simulation of the nets. To date there exist several approaches to model the different mesh types such as ring nets or diagonal meshes (Nicot 1999, Cazzani et al. 2002, Volkwein 2004). However, the consideration of chain link meshes has not yet been realised. Chain link meshes are normally found as standard fence structures. However, they also exist in setups using high-strength steel and wire bundles. These variants show an enormous capacity to retain loads e.g. rockfalls, and at the same time are very efficient due to their low demand of steel material. The increasing application of chain link mesh in barrier systems requires an accurate model is available to complete prototype studies. A new approach now aims to perform a Finite Element simulation of such chain link meshes. The main challenge herein is to achieve the net deformation behaviour that is observed in field tests also in the simulation. A simulation using simple truss elements would not work since it neglects the out-of-plane-height of the mesh construction providing important reserves for local and global high deformations. Thus addressing this, a specially developed Discrete Element is able to reconstruct the mechanical behaviour of the single chain wire (bundles). As input parameters it utilises typical properties such as longitudinal and transversal mesh widths, and break loads resulting from in-plane-tension tests and steel strength. The single chain elements then can be combined to a complete mesh (e.g. 130 x 65 mm, 3 - 4 mm wire with a strength of 1770 N-mm2). Combining these elements with a supporting structure consisting of posts, ropes and energy absorbers, enables the simulation of protection barriers used for natural hazards such as rockfalls or even landslides. The contribution explains the mechanical behaviour of the chain mesh, the calibration procedures and their application in flexible rockfall protection systems. The investigated meshes are built using three or four millimeter wire with a minimum yield strength of 1770 N-mm2: The maximal load in longitudinal mesh direction ranges about 130 - 380 kN-m and transversal 50 - 170 kN-m. The mesh size varies from 83 × 143 mm to 292 × 500 mm. References Cazzani, A., Mongiovi, L. and Frenez, T. (2002) Dynamic Finite Element Analysis of Interceptive Devices for Falling Rocks, International Journal of Rock Mechanics & Mining Sciences. 39,303-321. Volkwein, A. (2004) Numerische Simulation von flexiblen Steinschlagschutzsystemen. Diss. ETH Nr. 15641. Nicot, F. (1999) Etude du comportement méchanique des ouvrages souples de protection contre les éboulements rocheux. Diss. Ecole Centrale de Lyon.

Limits on neutral heavy lepton production from Z 0 decay

NASA Astrophysics Data System (ADS)

Akrawy, M. Z.; Alexander, G.; Allison, J.; Allport, P. P.; Anderson, K. J.; Armitage, J. C.; Arnison, G. T. J.; Ashton, P.; Azuelos, G.; Baines, J. T. M.; Ball, A. H.; Banks, J.; Barker, G. J.; Barlow, R. J.; Batley, J. R.; Becker, J.; Behnke, T.; Bell, K. W.; Bella, G.; Bethke, S.; Biebel, O.; Binder, U.; Bloodworth, I. J.; Bock, P.; Breuker, H.; Brown, R. M.; Brun, R.; Buijs, A.; Burckhart, H. J.; Capiluppi, P.; Carnegie, R. K.; Carter, A. A.; Carter, J. R.; Chang, C. Y.; Charlton, D. G.; Chrin, J. T. M.; Cohen, I.; Collins, W. J.; Conboy, J. E.; Couch, M.; Coupland, M.; Cuffiani, M.; Dado, S.; Dallavalle, G. M.; Debu, P.; Deninno, M. M.; Dieckmann, A.; Dittmar, M.; Dixit, M. S.; Duchovni, E.; Duerdoth, I. P.; Dumas, D.; El Mamouni, H.; Elcombe, P. A.; Estabrooks, P. G.; Etzion, E.; Fabbri, F.; Farthouat, P.; Fischer, H. M.; Fong, D. G.; French, M. T.; Fukunaga, C.; Gaidot, A.; Ganel, O.; Gary, J. W.; Gascon, J.; Geddes, N. I.; Gee, C. N. P.; Geich-Gimbel, C.; Gensler, S. W.; Gentit, F. X.; Giacomelli, G.; Gibson, V.; Gibson, W. R.; Gillies, J. D.; Goldberg, J.; Goodrick, M. J.; Gorn, W.; Granite, D.; Gross, E.; Grosse-Wiesman, P.; Grunhaus, J.; Hagedorn, H.; Hagemann, J.; Hansroul, M.; Hargrove, C. K.; Hart, J.; Hattersley, P. M.; Hauschild, M.; Hawkes, C. M.; Heflin, E.; Hemingway, R. J.; Heuer, R. D.; Hill, J. C.; Hillier, S. J.; Ho, C.; Hobbs, J. D.; Hobson, P. R.; Hochman, D.; Holl, B.; Homer, R. J.; Hou, S. R.; Howarth, C. P.; Hughes-Jones, R. E.; Humbert, R.; Igo-Kemenes, P.; Ihssen, H.; Imrie, D. C.; Jawahery, A.; Jeffreys, P. W.; Jeremie, H.; Jimack, M.; Jobes, M.; Jones, R. W. L.; Jovanovic, P.; Karlen, D.; Kawagoe, K.; Kawamoto, T.; Kellogg, R. G.; Kennedy, B. W.; Kleinwort, C.; Klem, D. E.; Knop, G.; Kobayashi, T.; Kokott, T. P.; Köpke, L.; Kowalewski, R.; Kreutzmann, H.; von Krogh, J.; Kroll, J.; Kuwano, M.; Kyberd, P.; Lafferty, G. D.; Lamarche, F.; Larson, W. J.; Layter, J. G.; Le Du, P.; Leblanc, P.; Lee, A. M.; Lellouch, D.; Lennert, P.; Lessard, L.; Levinson, L.; Lloyd, S. L.; Loebinger, F. K.; Lorah, J. M.; Lorazo, B.; Losty, M. J.; Ludwig, J.; Lupu, N.; Ma, J.; Macbeth, A. A.; Mannelli, M.; Marcellini, S.; Maringer, G.; Martin, A. J.; Martin, J. P.; Mashimo, T.; Mättig, P.; Maur, U.; McMahon, T. J.; McPherson, A. C.; Meijers, F.; Menszner, D.; Merritt, F. S.; Mes, H.; Michelini, A.; Middleton, R. P.; Mikenberg, G.; Miller, D. J.; Milstene, C.; Minowa, M.; Mohr, W.; Montanari, A.; Mori, T.; Moss, M. W.; Murphy, P. G.; Murray, W. J.; Nellen, B.; Nguyen, H. H.; Nozaki, M.; O'Dowd, A. J. P.; O'Neale, S. W.; O'Neill, B. P.; Oakham, F. G.; Odorici, F.; Ogg, M.; Oh, H.; Oreglia, M. J.; Orito, S.; Pansart, J. P.; Patrick, G. N.; Pawley, S. J.; Pfister, P.; Pilcher, J. E.; Pinfold, J. L.; Plane, D. E.; Poli, B.; Pouladdej, A.; Pritchard, T. W.; Quast, G.; Raab, J.; Redmond, M. W.; Rees, D. L.; Regimbald, M.; Riles, K.; Roach, C. M.; Robins, S. A.; Rollnik, A.; Roney, J. M.; Rossberg, S.; Rossi, A. M.; Routenburg, P.; Runge, K.; Runolfsson, O.; Sanghera, S.; Sansum, R. A.; Sasaki, M.; Saunders, B. J.; Schaile, A. D.; Schaile, O.; Schappert, W.; Scharff-Hansen, P.; von der Schmitt, H.; Schreiber, S.; Schwarz, J.; Shapira, A.; Shen, B. C.; Sherwood, P.; Simon, A.; Singh, P.; Siroli, G. P.; Skuja, A.; Smith, A. M.; Smith, T. J.; Snow, G. A.; Spreadbury, E. J.; Springer, R. W.; Sproston, M.; Stephens, K.; Stier, H. E.; Ströhmer, R.; Strom, D.; Takeda, H.; Takeshita, T.; Tsukamoto, T.; Turner, M. F.; Tysarczyk-Niemeyer, G.; Van den plas, D.; VanDalen, G. J.; Vasseur, G.; Virtue, C. J.; Wagner, A.; Wahl, C.; Ward, C. P.; Ward, D. R.; Waterhouse, J.; Watkins, P. M.; Watson, A. T.; Watson, N. K.; Weber, M.; Weisz, S.; Wells, P.; Wermes, N.; Weymann, M.; Wilson, G. W.; Wilson, J. A.; Wingerter, I.; Winterer, V.-H.; Wood, N. C.; Wotton, S.; Wuensch, B.; Wyatt, T. R.; Yaari, R.; Yang, Y.; Yekutieli, G.; Yoshida, T.; Zeuner, W.; Zorn, G. T.

1990-09-01

Data taken with the OPAL detector at LEP during a scan of the Z 0 resonance were searched for evidence of neutral heavy leptons that decay via mixing. Four different decay modes of the neutral heavy lepton are considered: L0→ eW∗, L0→μ W∗, L0→τ W∗, and L0→ vZ∗. No evidence is seen of a neutral heavy lepton signal; branching fraction limits in the range of 10 -3-10 -4 are set for Z0→ L0overlineL0 and for Z0→ voverlineL0 ( oroverlinevL0) relative to Z 0→hadrons.

Characteristics of an Integrated Optics Ring Resonator.

DTIC Science & Technology

1983-08-01

from KNO 3 Melts .......................... 42 V.A.l. Introduction.....................42 V.A.2. measurement of Waveguide Characteristics. ...... 44...crease the resonator finesse. The waveguides were fabricated by ion exchange from a KNO3 melt at 400 0C. Channel definition was accomplished by a... melts . This technique will be described first. Previously, we used diffusion from metallic silver films. Although very low loss waveguides were

Analysis of Some Combination-Overtone Infrared Bands of (SO3)-S-32-O-16.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maki, Arthur G.; Blake, Thomas A.; Sams, Robert L.

2004-06-01

Several new bands for 32S16O3 have been measured and analyzed. The principal bands observed were v1+v2 (at 1561 cm-1), v1+v4 (at 1594 cm -1) v3+ v4 (at 1918 cm-1), and 3v3 (at 4136 cm-1). Except for 3v3, these bands are very complicated because of (a) the Coriolis coupling between v2 and v4 (b) the Fermi resonance between v1 and 2v4, (c) the Fermi resonance between v1 and 2v2, (d) ordinary l-type resonance that couples levels that differ by 2 in both the k and l quantum numbers, and (e) the vibrational l-type resonance between the A1 and A2 levels ofmore » v3+v4. The unraveling of the complex pattern of these bands was facilitated by a systematic approach to the understanding of the various interactions. Fortunately, previous work on the fundamentals permitted good estimates of many constants necessary to begin the assignments and the fit of the measurements. In addition, the use of hot band transitions accompanying the v3 band was an essential aid in fitting the v3+v4 transitions since these could be directly observed for only one of four interacting states. From the hot band analysis we find that the A1 vibrational level is 3.50cm-1 above the A2 level, i.e., r34=1.75236(7) cm-1.« less

Quantum resonances and regularity islands in quantum maps

PubMed

Sokolov; Zhirov; Alonso; Casati

2000-05-01

We study analytically as well as numerically the dynamics of a quantum map near a quantum resonance of an order q. The map is embedded into a continuous unitary transformation generated by a time-independent quasi-Hamiltonian. Such a Hamiltonian generates at the very point of the resonance a local gauge transformation described by the unitary unimodular group SU(q). The resonant energy growth is attributed to the zero Liouville eigenmodes of the generator in the adjoint representation of the group while the nonzero modes yield saturating with time contribution. In a vicinity of a given resonance, the quasi-Hamiltonian is then found in the form of power expansion with respect to the detuning from the resonance. The problem is related in this way to the motion along a circle in a (q2 - 1)-component inhomogeneous "magnetic" field of a quantum particle with q intrinsic degrees of freedom described by the SU(q) group. This motion is in parallel with the classical phase oscillations near a nonlinear resonance. The most important role is played by the resonances with the orders much smaller than the typical localization length q < l. Such resonances master for exponentially long though finite times the motion in some domains around them. Explicit analytical solution is possible for a few lowest and strongest resonances.

High Rydberg resonances in dielectronic recombination of pb(79+).

PubMed

Brandau, C; Bartsch, T; Hoffknecht, A; Knopp, H; Schippers, S; Shi, W; Müller, A; Grün, N; Scheid, W; Steih, T; Bosch, F; Franzke, B; Kozhuharov, C; Mokler, P H; Nolden, F; Steck, M; Stöhlker, T; Stachura, Z

2002-07-29

Dielectronic recombination resonances of Pb (79+) associated with 2s(1/2)-->2p(1/2) excitations were measured at the heavy-ion storage ring ESR at GSI. The fine structure of the energetically lowest resonance manifold Pb (78+)(1s(2)2p(1/2)20l(j)) at around 18 eV could partially be resolved, and rate coefficients on an absolute scale were obtained. A comparison of the experimental data with results of a fully relativistic theoretical approach shows that high-angular-momentum components up to j=31/2 significantly contribute to the total resonance strength demonstrating the necessity to revise the widespread notion of negligible high-angular-momentum contributions at least for very highly charged ions.

Study on the ternary mixed ligand complex of palladium(II)-aminophylline-fluorescein sodium by resonance Rayleigh scattering, second-order scattering and frequency doubling scattering spectrum and its analytical application.

PubMed

Chen, Peili; Liu, Shaopu; Liu, Zhongfang; Hu, Xiaoli

2011-01-01

The interaction between palladium(II)-aminophylline and fluorescein sodium was investigated by resonance Rayleigh scattering, second-order scattering and frequency doubling scattering spectrum. In pH 4.4 Britton-Robinson (BR) buffer medium, aminophylline (Ami) reacted with palladium(II) to form chelate cation([Pd(Ami)]2+), which further reacted with fluorescein sodium (FS) to form ternary mixed ligand complex [Pd(Ami)(FS)2]. As a result, resonance Rayleigh scattering (RRS), second-order scattering (SOS) and frequency doubling scattering spectrum (FDS) were enhanced. The maximum scattering wavelengths of [Pd(Ami)(FS)2] were located at 300 nm (RRS), 650 nm (SOS) and 304 nm (FDS). The scattering intensities were proportional to the Ami concentration in a certain range and the detection limits were 7.3 ng mL(-1) (RRS), 32.9 ng mL(-1) (SOS) and 79.1 ng mL(-1) (FDS), respectively. Based on it, the new simple, rapid, and sensitive scattering methods have been proposed to determine Ami in urine and serum samples. Moreover, the formation mechanism of [Pd(Ami)(FS)2] and the reasons for enhancement of RRS were fully discussed. Crown Copyright © 2010. Published by Elsevier B.V. All rights reserved.

Waveform inversion of oscillatory signatures in long-period events beneath volcanoes

USGS Publications Warehouse

Kumagai, H.; Chouet, B.A.; Nakano, M.

2002-01-01

The source mechanism of long-period (LP) events is examined using synthetic waveforms generated by the acoustic resonance of a fluid-filled crack. We perform a series of numerical tests in which the oscillatory signatures of synthetic LP waveforms are used to determine the source time functions of the six moment tensor components from waveform inversions assuming a point source. The results indicate that the moment tensor representation is valid for the odd modes of crack resonance with wavelengths 2L/n, 2W/n, n = 3, 5, 7, ..., where L and W are the crack length and width, respectively. For the even modes with wavelengths 2L/n, 2W/n, n = 2, 4, 6,..., a generalized source representation using higher-order tensors is required, although the efficiency of seismic waves radiated by the even modes is expected to be small. We apply the moment tensor inversion to the oscillatory signatures of an LP event observed at Kusatsu-Shirane Volcano, central Japan. Our results point to the resonance of a subhorizontal crack located a few hundred meters beneath the summit crater lakes. The present approach may be useful to quantify the source location, geometry, and force system of LP events, and opens the way for moment tensor inversions of tremor.

Distribution of 16S rRNA Methylases Among Different Species of Aminoglycoside-Resistant Enterobacteriaceae in a Tertiary Care Hospital in Poland.

PubMed

Piekarska, Katarzyna; Zacharczuk, Katarzyna; Wołkowicz, Tomasz; Rzeczkowska, Magdalena; Bareja, Elżbieta; Olak, Monika; Gierczyński, Rafał

2016-01-01

Aminoglycosides are a group of antimicrobial agents still the most commonly used in the treatment of life-threatening bacterial infections in human and animals. The emergence and spread of 16S rRNA methylases, which confer high-level resistance to the majority of clinically relevant aminoglycosides, constitute a major public health concern. Our goal was to evaluate the distribution of 16S rRNA methylases among different species of Enterobacteriaceae during a five month-long survey in a tertiary hospital in Warszawa, Poland. In the survey, a total of 1770 non-duplicate clinical isolates were collected from all hospital wards in a tertiary hospital in Warszawa, Poland. The survey was conducted between 19 April and 19 September 2010. The ability to produce 16S rRNA methylase was examined by determining MICs for gentamicin, kanamycin, amikacin by means of the agar dilution method. The isolates resistant to high concentration of aminoglycosides were PCR tested for genes: armA, rmtA, rmtB and rmtC. PCR products were subjected to DNA sequencing by the Sanger method. The genetic similarity of the ArmA-producing isolates was analysed by pulsed-filed gel electrophoresis (PFGE). ArmA was the only 16S rRNA methylase detected in 20 of 1770 tested isolates. The overall prevalence rate of ArmA was 1.13%. In K. pneumoniae (n = 742), P. mirabilis (n = 130), and E. cloacae (n = 253) collected in the survey, the prevalence of ArmA was 0.4%, 0.8% and 5.9%, respectively. The PFGE revealed both horizontal and clonal spread of the armA gene in the hospital. The prevalence of 16S rRNA methylase ArmA reported in this study is significantly higher than observed in other countries in Europe.

Phenomenology of pseudotensor mesons and the pseudotensor glueball

NASA Astrophysics Data System (ADS)

Koenigstein, Adrian; Giacosa, Francesco

2016-12-01

We study the decays of the pseudotensor mesons (π2(1670), K2(1770), η2(1645), η2(1870)) interpreted as the ground-state nonet of 11D2 bar{q}q states using interaction Lagrangians which couple them to pseudoscalar, vector, and tensor mesons. While the decays of π2(1670) and K2(1770) can be well described, the decays of the isoscalar states η2(1645) and η2(1870) can be brought in agreement with the present experimental data only if the mixing angle between nonstrange and strange states is surprisingly large (about -42°, similar to the mixing in the pseudoscalar sector, in which the chiral anomaly is active). Such a large mixing angle is however at odd with all other conventional quark-antiquark nonets: if confirmed, a deeper study of its origin will be needed in the future. Moreover, the bar{q}q assignment of pseudotensor states predicts that the ratio [η2(1870) → a2(1320) π]/[η2(1870) → f2(1270) η] is about 23.5. This value is in agreement with Barberis et al., (20.4 ± 6.6), but disagrees with the recent reanalysis of Anisovich et al., (1.7 ± 0.4). Future experimental studies are necessary to understand this puzzle. If Anisovich's value is confirmed, a simple nonet of pseudoscalar mesons cannot be able to describe data (different assignments and/or additional states, such as an hybrid state, will be needed). In the end, we also evaluate the decays of a pseudoscalar glueball into the aforementioned conventional bar{q}q states: a sizable decay into K^{ast}2(1430) K and a2(1230) π together with a vanishing decay into pseudoscalar-vector pairs (such as ρ(770) π and K^{ast}(892) K) are expected. This information can be helpful in future studies of glueballs at the ongoing BESIII and at the future PANDA experiments.

Ultraviolet resonance Raman spectroscopy for the detection of cocaine in oral fluid

NASA Astrophysics Data System (ADS)

D'Elia, Valentina; Montalvo, Gemma; Ruiz, Carmen García; Ermolenkov, Vladimir V.; Ahmed, Yasmine; Lednev, Igor K.

2018-01-01

Detecting and quantifying cocaine in oral fluid is of significant importance for practical forensics. Up to date, mainly destructive methods or biochemical tests have been used, while spectroscopic methods were only applied to pretreated samples. In this work, the possibility of using resonance Raman spectroscopy to detect cocaine in oral fluid without pretreating samples was tested. It was found that ultraviolet resonance Raman spectroscopy with 239-nm excitation allows for the detection of cocaine in oral fluid at 10 μg/mL level. Further method development will be needed for reaching the practically useful levels of cocaine detection.

Clinical Pharmacokinetics of Levornidazole in Elderly Subjects and Dosing Regimen Evaluation Using Pharmacokinetic/Pharmacodynamic Analysis.

PubMed

Guo, Beining; He, Gaoli; Wu, Xiaojie; Yu, Jicheng; Cao, Guoying; Li, Yi; Fan, Yaxin; Chen, Yuancheng; Shi, Yaoguo; Zhang, Yingyuan; Zhang, Jing

2017-07-01

Levornidazole, the levo-isomer of ornidazole, is a third-generation nitroimidazole derivative newly developed after metronidazole, tinidazole, and ornidazole. An open-label, parallel-controlled, single-dose study was conducted for the investigation of the pharmacokinetic (PK) profile of levornidazole and its metabolites in healthy elderly Chinese subjects, and for the evaluation of 2 dosing regimens in the elderly. Levornidazole was intravenously administered at 500 mg to healthy elderly (aged 60-80 years) or young subjects (aged 19-45 years). The PK profiles of levornidazole and its metabolites in elderly subjects were evaluated and compared with those in the young group. WinNonlin software was used for simulating the PK profile of levornidazole in the elderly population following the dosing regimens of 500 mg BID and 750 mg once daily for 7 days. Monte Carlo simulation was used for estimating the cumulative fraction of response and probability of target attainment of both dosing regimens against Bacteroides spp. The C max , AUC 0-24, and AUC 0-∞ values of levornidazole in the elderly group were 11.98 μg/mL, 131.36 μg·h/mL, and 173.61 μg·h/mL, respectively. The t 1/2 , CL t , and mean residence time from time 0 to infinity were 12.21 hours, 2.91 L/h, and 16.46 hours. The metabolic ratios of metabolites (M) 1, 2, 4, and 6 were <3.0%, and that of M16 was 17.70%. The urinary excretion values of levornidazole, M1, M2, M4, M6, and M16 over 96 hours were 10.21%, 0.92%, ~0%, 2.69%, 0.54%, and 41.98%. The PK properties of levornidazole and the urinary excretion of all metabolites were not statistically different between the 2 groups. The cumulative fraction of response was >90% against B fragilis and other Bacteroides spp, and the probability of target attainment was >90% when the minimum inhibitory concentration was ≤1 μg/mL, in both groups. No dosing regimen adjustment is suggested when levornidazole is used in elderly patients with normal hepatic functioning and mild renal dysfunction. The findings from the PK/PD analysis imply that both regimens may achieve satisfactory clinical and microbiological efficacy against anaerobic infections in elderly patients. Chinese Clinical Trial Registry (http://www.chictr.org.cn) identifier: ChiCTR-OPC-16007938. Copyright © 2017 Elsevier HS Journals, Inc. All rights reserved.

Syntheses, X-ray structures, solid state high-field electron paramagnetic resonance, and density-functional theory investigations on chloro and aqua Mn(II) mononuclear complexes with amino-pyridine pentadentate ligands.

PubMed

Hureau, Christelle; Groni, Sihem; Guillot, Régis; Blondin, Geneviève; Duboc, Carole; Anxolabéhère-Mallart, Elodie

2008-10-20

The two pentadentate amino-pyridine ligands L5(2) and L5(3) (L5(2) and L5(3) stand for the N-methyl-N,N',N'-tris(2-pyridylmethyl)ethane-1,2-diamine and the N-methyl-N,N',N'-tris(2-pyridylmethyl)propane-1,3-diamine, respectively) were used to synthesize four mononuclear Mn(II) complexes, namely [(L5(2))MnCl](PF6) (1(PF6)), [(L5(3))MnCl](PF6) (2(PF6)), [(L5(2))Mn(OH2)](BPh4)2 (3(BPh4)2), and [(L5(3))Mn(OH2)](BPh4)2 (4(BPh4)2). The X-ray diffraction studies revealed different configurations for the ligand L5(n) (n = 2, 3) depending on the sixth exogenous ligand and/or the counterion. Solid state high-field electron paramagnetic resonance spectra were recorded on complexes 1-4 as on previously described mononuclear Mn(II) systems with tetra- or hexadentate amino-pyridine ligands. Positive and negative axial zero-field splitting (ZFS) parameters D were determined whose absolute values ranged from 0.090 to 0.180 cm(-1). Density-functional theory calculations were performed unraveling that, in contrast with chloro systems, the spin-spin and spin-orbit coupling contributions to the D-parameter are comparable for mixed N,O-coordination sphere complexes.

Le niobate de lithium a haute temperature pour les applications ultrasons =

NASA Astrophysics Data System (ADS)

De Castilla, Hector

L'objectif de ce travail de maitrise en sciences appliquees est de trouver puis etudier un materiau piezoelectrique qui est potentiellement utilisable dans les transducteurs ultrasons a haute temperature. En effet, ces derniers sont actuellement limites a des temperatures de fonctionnement en dessous de 300°C a cause de l'element piezoelectrique qui les compose. Palier a cette limitation permettrait des controles non destructifs par ultrasons a haute temperature. Avec de bonnes proprietes electromecaniques et une temperature de Curie elevee (1200°C), le niobate de lithium (LiNbO 3) est un bon candidat. Mais certaines etudes affirment que des processus chimiques tels que l'apparition de conductivite ionique ou l'emergence d'une nouvelle phase ne permettent pas son utilisation dans les transducteurs ultrasons au-dessus de 600°C. Cependant, d'autres etudes plus recentes ont montre qu'il pouvait generer des ultrasons jusqu'a 1000°C et qu'aucune conductivite n'etait visible. Une hypothese a donc emerge : une conductivite ionique est presente dans le niobate de lithium a haute temperature (>500°C) mais elle n'affecte que faiblement ses proprietes a hautes frequences (>100 kHz). Une caracterisation du niobate de lithium a haute temperature est donc necessaire afin de verifier cette hypothese. Pour cela, la methode par resonance a ete employee. Elle permet une caracterisation de la plupart des coefficients electromecaniques avec une simple spectroscopie d'impedance electrochimique et un modele reliant de facon explicite les proprietes au spectre d'impedance. Il s'agit de trouver les coefficients du modele permettant de superposer au mieux le modele avec les mesures experimentales. Un banc experimental a ete realise permettant de controler la temperature des echantillons et de mesurer leur impedance electrochimique. Malheureusement, les modeles actuellement utilises pour la methode par resonance sont imprecis en presence de couplages entre les modes de vibration. Cela implique de posseder plusieurs echantillons de differentes formes afin d'isoler chaque mode principal de vibration. De plus, ces modeles ne prennent pas bien en compte les harmoniques et modes en cisaillement. C'est pourquoi un nouveau modele analytique couvrant tout le spectre frequentiel a ete developpe afin de predire les resonances en cisaillement, les harmoniques et les couplages entre les modes. Neanmoins, certains modes de resonances et certains couplages ne sont toujours pas modelises. La caracterisation d'echantillons carres a pu etre menee jusqu'a 750°C. Les resultats confirment le caractere prometteur du niobate de lithium. Les coefficients piezoelectriques sont stables en fonction de la temperature et l'elasticite et la permittivite ont le comportement attendu. Un effet thermoelectrique ayant un effet similaire a de la conductivite ionique a ete observe ce qui ne permet pas de quantifier l'impact de ce dernier. Bien que des etudes complementaires soient necessaires, l'intensite des resonances a 750°C semble indiquer que le niobate de lithium peut etre utilise pour des applications ultrasons a hautes frequences (>100 kHz).

Bypass of the maxillary artery to proximal middle cerebral artery.

PubMed

Ma, Lin; Ren, He-cheng; Huang, Ying

2015-03-01

The objective of this work was to explore the feasibility of bypass between the maxillary artery (MA) and proximity of middle cerebral artery (MCA). Ten fixed and perfused adult cadaver heads were dissected bilaterally, 20 sides in total. The superficial temporal artery and its 2 branches were dissected, and outer diameters were measured. The MA and its branch were exposed as well as deep temporal artery; outer diameter of MA was measured. The lengths between the external carotid artery, internal carotid artery, maxillary artery, and proximal middle cerebral artery were measured. Ten healthy adults as targets (20 sides), inner diameter and blood flow dynamic parameters of the common carotid artery, external carotid artery, internal carotid artery, maxillary artery, superficial temporal artery, and its 2 branches were done with ultrasound examination. The mean outer diameter of MA (2.60 ± 0.20 mm) was larger than that of the temporal artery trunk (1.70 ± 0.30 mm). The mean lengths of graft vessels between the internal carotid artery, external carotid artery, and the bifurcation section of MCA (171.00 ± 2.70 and 162.40 ± 2.60 mm) were longer than the mean lengths of graft vessels between MA and MCA bifurcation section (61.70 ± 1.50 mm). In adults, the mean blood flow of the second part of MA (62.70 ± 13.30 mL/min) was more than that of the 2 branches of the superficial temporal artery (15.90 ± 3.70 mL/min and 17.70 ± 4.10 ml/min). Bypass between the maxillary artery and proximity of middle cerebral artery is feasible. It is a kind of effective high flow bypass with which the graft vessel is shorter and straighter than the bypass between internal carotid artery or external carotid artery and proximity of middle cerebral artery.

10Be exposure age chronology of the last glaciation of the Roháčská Valley in the Western Tatra Mountains, central Europe

NASA Astrophysics Data System (ADS)

Engel, Zbyněk; Mentlík, Pavel; Braucher, Régis; Křížek, Marek; Pluháčková, Markéta; Arnold, Maurice; Aumaître, Georges; Bourlès, Didier; Keddadouche, Karim; Aster Team; Arnold, Maurice; Aumaître, Georges; Bourlès, Didier; Keddadouche, Karim

2017-09-01

10Be exposure ages from moraines and bedrock sites in the Roháčská Valley provide chronology of the last glaciation in the largest valley of the Western Tatra Mts., the Western Carpathians. The minimum apparent exposure age of 19.4 ± 2.1 ka obtained for the oldest sampled boulder and the mean age of 18.0 ± 0.8 ka calculated for the terminal moraine indicate that the oldest preserved moraine was probably deposited at the time of the global Last Glacial Maximum (LGM). The age of this moraine coincides with the termination of the maximum glacier expansion in other central European ranges, including the adjacent High Tatra Mts. and the Alps. The equilibrium line altitude (ELA) of the LGM glacier in the Roháčská Valley, estimated at 1400-1410 m a.s.l., was 50-80 m lower than in the eastern part of the range, indicating a positive ELA gradient from west to east among the north-facing glaciers in the Tatra Mts. Lateglacial glacier expansion occurred no later than 13.4 ± 0.5 ka and 11.9 ± 0.5 ka, as indicated by the mean exposure ages calculated for re-advance moraines. This timing is consistent with the exposure age chronology of the last Lateglacial re-advance in the High Tatra Mts., Alps and lower mountain ranges in central Europe. The ELA in the Roháčská Valley estimated at 1690-1770 m a.s.l. in this period was located 130-300 m lower than in the north-facing valleys in the High Tatra Mts. 10Be exposure ages obtained for a rock glacier constrains the timing of this landform stabilization in the Salatínska Valley and provides the first chronological evidence for the Lateglacial activity of rock glaciers in the Carpathians.

Use of the Etonogestrel Implant and Levonorgestrel Intrauterine Device Beyond the U.S. Food and Drug Administration–Approved Duration

PubMed Central

McNicholas, Colleen; Maddipati, Ragini; Zhao, Qiuhong; Swor, Erin; Peipert, Jeffrey F.

2014-01-01

Objective To evaluate the effectiveness of the contraceptive implant and the 52mg hormonal intrauterine device (IUD) in women using the method beyond the current U.S. Food and Drug Administration–approved duration of 3 and 5 years respectively. Methods Women willing to continue using their implant or 52mg levonorgestrel IUD (LNG-IUD) beyond the FDA-approved duration were followed prospectively for contraceptive effectiveness. Unintended pregnancy rate per 100 women-years was calculated. Implant users are offered periodic venipuncture for analysis of serum etonogestrel levels. The Kruskal-Wallis test was used to compare the etonogestrel levels across BMI groups. Results Implant users (n=237) have contributed 229.4 women-years of follow-up, with 123 using the etonogestrel implant for 4 years, and 34 using it for 5 years. Zero pregnancies have been documented, for a failure rate of 0 (one-sided 97.5% CI: 0, 1.61) per 100 women-years. Among 263 LNG-IUD users, 197.7 women-years of follow-up have been completed. One pregnancy was confirmed, for a failure rate of 0.51 (95% CI: 0.01, 2.82) per 100 women-years. Among implant users with serum etonogestrel results, the median and range of etonogestrel level at 3 years of use was 188.8 pg/mL (range 63.8, 802.6) and 177.0 pg/mL (67.9, 470.5) at 4 years of use. Etonogestrel levels did not differ by BMI at either time point (3 years: p=0.79; 4 years: p=0.47). Conclusion Preliminary findings indicate the contraceptive implant and 52mg hormonal IUD continue to be highly-effective for an additional year, beyond the FDA approved 3 and 5 years.. Serum etonogestrel levels indicate the implant contains adequate hormone for ovulation suppression at the end of both 3 and 4 years of use. PMID:25730221

Cerebral signal intensity abnormalities on T2-weighted MR images in HIV patients with highly active antiretroviral therapy: relationship with clinical parameters and interval changes.

PubMed

Hanning, Uta; Husstedt, Ingo W; Niederstadt, Thomas-Ulrich; Evers, Stefan; Heindel, Walter; Kloska, Stephan P

2011-09-01

The aim of this study was to assess the relationship between immune state and cerebral signal intensity abnormalities (SIAs) on T2-weighted magnetic resonance images in subjects with human immunodeficiency virus type 1 infection and highly active antiretroviral therapy. Thirty-two subjects underwent a total of 109 magnetic resonance studies. The presence of human immunodeficiency virus-associated neurocognitive disorder, categorized CD4(+) T lymphocyte count, and plasma viral load were assessed for relationship with the severity and interval change of SIAs for different anatomic locations of the brain. Subjects with multifocal patterns of SIAs had CD4(+) cell counts < 200 cells/μL in 66.0%, whereas subjects with diffuse patterns of SIAs had CD4(+) cell counts < 200 cells/μL in only 31.4% (P < .001). Subjects without SIAs in the basal ganglia had CD4(+) cell counts < 200 cells/μL in 37.0%, whereas subjects with minor and moderate SIAs in the basal ganglia had CD4(+) cell counts < 200 cells/μL in 78.3% and 80.0%, respectively (P < .005). The percentage of subjects with CD4(+) cell counts < 200 cells/μL was 85.7% when there were progressive periventricular SIA changes and 45.5% when periventricular SIA changes were stable in follow-up (P < .05). The presence and progression of cerebral SIAs on T2-weighted magnetic resonance images reflecting cerebral infection with human immunodeficiency virus are significantly related to impaired immune state as measured by CD4(+) cell count. Copyright © 2011 AUR. Published by Elsevier Inc. All rights reserved.

Bodily Tides Near Spin-Orbit Resonances

DTIC Science & Technology

2012-01-01

radial term may cause an equipotential - surface variation of about 10 cm. This magnitude is large enough to be observed by future missions and should...U (r) = ∞∑ l=2 Ul(r) = ∞∑ l=2 kl ( R r )l+1 Wl(R, r∗), (2) R now being the mean equatorial radius of the primary, R = (R, φ, λ) being a surface point...rheology. For a homogeneous incompressible spherical primary of density ρ, surface gravity g, and rigidity μ, the static Love number of degree l is

Bonding in Heavier Group 14 Zero-Valent Complexes-A Combined Maximum Probability Domain and Valence Bond Theory Approach.

PubMed

Turek, Jan; Braïda, Benoît; De Proft, Frank

2017-10-17

The bonding in heavier Group 14 zero-valent complexes of a general formula L 2 E (E=Si-Pb; L=phosphine, N-heterocyclic and acyclic carbene, cyclic tetrylene and carbon monoxide) is probed by combining valence bond (VB) theory and maximum probability domain (MPD) approaches. All studied complexes are initially evaluated on the basis of the structural parameters and the shape of frontier orbitals revealing a bent structural motif and the presence of two lone pairs at the central E atom. For the VB calculations three resonance structures are suggested, representing the "ylidone", "ylidene" and "bent allene" structures, respectively. The influence of both ligands and central atoms on the bonding situation is clearly expressed in different weights of the resonance structures for the particular complexes. In general, the bonding in the studied E 0 compounds, the tetrylones, is best described as a resonating combination of "ylidone" and "ylidene" structures with a minor contribution of the "bent allene" structure. Moreover, the VB calculations allow for a straightforward assessment of the π-backbonding (E→L) stabilization energy. The validity of the suggested resonance model is further confirmed by the complementary MPD calculations focusing on the E lone pair region as well as the E-L bonding region. Likewise, the MPD method reveals a strong influence of the σ-donating and π-accepting properties of the ligand. In particular, either one single domain or two symmetrical domains are found in the lone pair region of the central atom, supporting the predominance of either the "ylidene" or "ylidone" structures having one or two lone pairs at the central atom, respectively. Furthermore, the calculated average populations in the lone pair MPDs correlate very well with the natural bond orbital (NBO) populations, and can be related to the average number of electrons that is backdonated to the ligands. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Competition between L- and V-type transitions in interference stabilization of Rydberg atoms.

PubMed

Fedorov, M; Poluektov, N

1998-01-19

The problem of Interference Stabilization of Rydberg atoms is considered. Two kinds of Raman-type transitions can be responsible for the effect: L-type transitions via the continuum and V-type transitions via lower resonant atomic levels. The main distinctions between L- and V- stabilization are described. The conditions under which each of these two effects can exist are found and discussed.

Neutron Spin Resonance in the 112-Type Iron-Based Superconductor

NASA Astrophysics Data System (ADS)

Xie, Tao; Gong, Dongliang; Ghosh, Haranath; Ghosh, Abyay; Soda, Minoru; Masuda, Takatsugu; Itoh, Shinichi; Bourdarot, Frédéric; Regnault, Louis-Pierre; Danilkin, Sergey; Li, Shiliang; Luo, Huiqian

2018-03-01

We use inelastic neutron scattering to study the low-energy spin excitations of the 112-type iron pnictide Ca0.82La0.18Fe0.96Ni0.04As2 with bulk superconductivity below Tc=22 K . A two-dimensional spin resonance mode is found around E =11 meV , where the resonance energy is almost temperature independent and linearly scales with Tc along with other iron-based superconductors. Polarized neutron analysis reveals the resonance is nearly isotropic in spin space without any L modulations. Because of the unique monoclinic structure with additional zigzag arsenic chains, the As 4 p orbitals contribute to a three-dimensional hole pocket around the Γ point and an extra electron pocket at the X point. Our results suggest that the energy and momentum distribution of the spin resonance does not directly respond to the kz dependence of the fermiology, and the spin resonance intrinsically is a spin-1 mode from singlet-triplet excitations of the Cooper pairs in the case of weak spin-orbital coupling.

Whispering gallery mode resonators for rapid label-free biosensing in small volume droplets.

PubMed

Wildgen, Sarah M; Dunn, Robert C

2015-03-23

Rapid biosensing requires fast mass transport of the analyte to the surface of the sensing element. To optimize analysis times, both mass transport in solution and the geometry and size of the sensing element need to be considered. Small dielectric spheres, tens of microns in diameter, can act as label-free biosensors using whispering gallery mode (WGM) resonances. WGM resonances are sensitive to the effective refractive index, which changes upon analyte binding to recognition sites on functionalized resonators. The spherical geometry and tens of microns diameter of these resonators provides an efficient target for sensing while their compact size enables detection in limited volumes. Here, we explore conditions leading to rapid analyte detection using WGM resonators as label-free sensors in 10 μL sample droplets. Droplet evaporation leads to potentially useful convective mixing, but also limits the time over which analysis can be completed. We show that active droplet mixing combined with initial binding rate measurements is required for accurate nanomolar protein quantification within the first minute following injection.

Edge waves and resonances in two-dimensional phononic crystal plates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hsu, Jin-Chen, E-mail: hsujc@yuntech.edu.tw; Hsu, Chih-Hsun

2015-05-07

We present a numerical study on phononic band gaps and resonances occurring at the edge of a semi-infinite two-dimensional (2D) phononic crystal plate. The edge supports localized edge waves coupling to evanescent phononic plate modes that decay exponentially into the semi-infinite phononic crystal plate. The band-gap range and the number of edge-wave eigenmodes can be tailored by tuning the distance between the edge and the semi-infinite 2D phononic lattice. As a result, a phononic band gap for simultaneous edge waves and plate waves is created, and phononic cavities beside the edge can be built to support high-frequency edge resonances. Wemore » design an L3 edge cavity and analyze its resonance characteristics. Based on the band gap, high quality factor and strong confinement of resonant edge modes are achieved. The results enable enhanced control over acoustic energy flow in phononic crystal plates, which can be used in designing micro and nanoscale resonant devices and coupling of edge resonances to other types of phononic or photonic crystal cavities.« less

Earthquake behavior of the Enriquillo fault zone, Haiti revealed by interactive terrain visualization

NASA Astrophysics Data System (ADS)

Cowgill, E.; Bernardin, T. S.; Oskin, M. E.; Bowles, C. J.; Yikilmaz, M. B.; Kreylos, O.; Elliott, A. J.; Bishop, M. S.; Gold, R. D.; Morelan, A.; Bawden, G. W.; Hamann, B.; Kellogg, L. H.

2010-12-01

The Mw 7.0 January 12, 2010 Haiti earthquake ended 240 years of relative quiescence following earthquakes that destroyed Port-au-Prince in 1751 and 1770. We place the 2010 rupture in the context of past earthquakes and future hazards by using remote analysis of airborne LiDAR to observe the topographic expression of active faulting and develop a new conceptual model for the earthquake behavior of the eastern Enriquillo fault zone (EFZ). In this model, the 2010 event occupies a long-lived segment boundary at a stepover within the EFZ separating fault segments that likely ruptured in 1751 and 1770, explaining both past clustering and the lack of 2010 surface rupture. Immediately following the 2010 earthquake, an airborne LiDAR point cloud containing over 2.7 billion point measurements of surface features was collected by the Rochester Inst. of Technology. To analyze these data, we capitalize on the human capacity to visually identify meaningful patterns embedded in noisy data by conducting interactive visual analysis of the entire 66.8 GB Haiti terrain data in a 4-sided, 800 ft3 immersive virtual-reality environment at the UC Davis KeckCAVES using the software tools LiDAR Viewer (to analyze point cloud data) and Crusta (for 3D surficial geologic mapping on DEM data). We discovered and measured landforms displaced by past surface-rupturing earthquakes and remotely characterized the regional fault geometry. Our analysis of the ~50 km long reach of EFZ spanning the 2010 epicenter indicates that geomorphic evidence of active faulting is clearer east of the epicenter than to the west. West of the epicenter, and in the region of the 2010 rupture, the fault is poorly defined along an embayed, low-relief range front, with little evidence of recent surface rupture. In contrast, landform offsets of 6 to 50 m along the reach of the EFZ east of the epicenter and closest to Port-au-Prince attest to repeated recent surface-rupturing earthquakes here. Specifically, we found and documented offset landforms including fluvial terrace risers near Dumay (6.3 +0.9/-1.3 m) and Chauffard/Jameau (32.2 +1.8/-3.1 m), a channel (52 +18/-13 m) ~500 m east of the Chauffard/Jameau site, and an alluvial fan near Fayette (8.6 +2.8/-2.5 m). Based on the fault-trace morphology and distribution of sites where we see 6-8 m offsets, we estimate the probable along-strike extent of past surface rupture was 40 to 60 km along this fault reach. Application of moment-rupture area relationships to these observations suggest that an earthquake similar to, or larger than the Mw 7.0 2010 event is possible along the Enriquillo fault near Port-au-Prince. We deduce that the 2010 earthquake was a relatively small event on a boundary between fault segments that ruptured in 1751 and 1770, based on new analysis of historical damage reports and the gap of well-defined fault-zone morphology where the 2010 earthquake occurred.

Microcavity surface plasmon resonance bio-sensors

NASA Astrophysics Data System (ADS)

Mosavian, Nazanin

This work discusses a miniature surface plasmon biosensor which uses a dielectric sub- micron diameter core with gold spherical shell. The shell has a subwavelength nanoaperture believed to excite stationary plasmon resonances at the biosensor's surface. The sub-micron cavity enhances the measurement sensitivity of molecules binding to the sensor surface. We used visible-range optical spectroscopy to study the wavelength shift as bio-molecules absorbed-desorbed at the shell surface. We also used Scanning Electron Microscopy (SEM) and Focused Ion Beam (FIB) ablation to study the characteristics of microcavity surface plasmon resonance sensor (MSPRS) and the inner structure formed with metal deposition and its spectrum. We found that resonances at 580 nm and 670 nm responded to bound test agents and that Surface Plasmon Resonance (SPR) sensor intensity could be used to differentiate between D-glucose and L-glucose. The responsiveness of the system depended upon the mechanical integrity of the metallic surface coating.

Rapid Detection of Infectious Envelope Proteins by Magnetoplasmonic Toroidal Metasensors.

PubMed

Ahmadivand, Arash; Gerislioglu, Burak; Manickam, Pandiaraj; Kaushik, Ajeet; Bhansali, Shekhar; Nair, Madhavan; Pala, Nezih

2017-09-22

Unconventional characteristics of magnetic toroidal multipoles have triggered researchers to study these unique resonant phenomena by using both 3D and planar resonators under intense radiation. Here, going beyond conventional planar unit cells, we report on the observation of magnetic toroidal modes using artificially engineered multimetallic planar plasmonic resonators. The proposed microstructures consist of iron (Fe) and titanium (Ti) components acting as magnetic resonators and torus, respectively. Our numerical studies and following experimental verifications show that the proposed structures allow for excitation of toroidal dipoles in the terahertz (THz) domain with the experimental Q-factor of ∼18. Taking the advantage of high-Q toroidal line shape and its dependence on the environmental perturbations, we demonstrate that room-temperature toroidal metasurface is a reliable platform for immunosensing applications. As a proof of concept, we utilized our plasmonic metasurface to detect Zika-virus (ZIKV) envelope protein (with diameter of 40 nm) using a specific ZIKV antibody. The sharp toroidal resonant modes of the surface functionalized structures shift as a function of the ZIKV envelope protein for small concentrations (∼pM). The results of sensing experiments reveal rapid, accurate, and quantitative detection of envelope proteins with the limit of detection of ∼24.2 pg/mL and sensitivity of 6.47 GHz/log(pg/mL). We envision that the proposed toroidal metasurface opens new avenues for developing low-cost, and efficient THz plasmonic sensors for infection and targeted bioagent detection.

Physicochemical perspectives (aggregation, structure and dynamics) of interaction between pluronic (L31) and surfactant (SDS).

PubMed

Prameela, G K S; Phani Kumar, B V N; Pan, A; Aswal, V K; Subramanian, J; Mandal, A B; Moulik, S P

2015-11-11

The influence of the water soluble non-ionic tri-block copolymer PEO-PPO-PEO [poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide)] i.e., E2P16E2 (L31) on the microstructure and self-aggregation dynamics of the anionic surfactant sodium dodecylsulfate (SDS) in aqueous solution was investigated using cloud point (CP), isothermal titration calorimetry (ITC), high resolution nuclear magnetic resonance (NMR), electron paramagnetic resonance (EPR), and small-angle neutron scattering (SANS) measurements. CP provided the thermodynamic information on the Gibbs free energy, enthalpy, entropy and heat capacity changes pertaining to the phase separation of the system at elevated temperature. The ITC and NMR self-diffusion measurements helped to understand the nature of the binding isotherms of SDS in the presence of L31 in terms of the formation of mixed aggregates and free SDS micelles in solution. EPR analysis provided the micro-viscosity of the spin probe 5-DSA in terms of rotational correlation time. The SANS study indicated the presence of prolate ellipsoidal mixed aggregates, whose size increased with the increasing addition of L31. At a large [L31], SANS also revealed the progressive decreasing size of the ellipsoidal mixed aggregates of SDS-L31 into nearly globular forms with the increasing SDS addition. Wrapping of the spherical SDS micelles by L31 was also corroborated from (13)C NMR and SANS measurements.

Landmine Detection by Nuclear Quadrupole Resonance (NQR)

DTIC Science & Technology

2004-12-01

14N nuclei present in the explosive (Hirshfeld and Klainer, 1980; Grechishkin, 1992; Rowe and Smith, 1996; Garroway et al., 2001; Deas et al., 2002...Mater. Chem., 7 (2), 229-235. Garroway , A.N., Buess, M.L., Miller, J.B., Suits, B.H., Hibbs, A.D., Barrall, G.A., Matthews, R. and Burnett, L.J

Applications of small surface plasmon resonance sensors for biochemical monitoring

NASA Astrophysics Data System (ADS)

Masson, Jean-Francois; Battaglia, Tina M.; Beaudoin, Stephen; Booksh, Karl S.

2004-12-01

The development of small surface plasmon resonance (SPR) sensors to detect biological markers for myocardial ischemia (MI), spinal muscular atrophy (SMA), and wound healing was achieved at low ng/mL and in less than 10 minutes. The markers of interest for MIs are myoglobin (MG) and cardiac Troponin I (cTnI). The limits of detection for these markers are respectively 600 pg/mL and 1.4 ng/mL in saline solution. To study SMA, the level of survival motor neuron protein (SMN) was investigated. A limit of detection of 990 pg/mL was achieved for the detection of SMN. The interactions of SMN with MG decreased the signal for both SMN and MG. Interleukin 6 and tumor necrosis factor alpha (TNFa) were investigated to monitor wound healing. The sensor's performance in more complex solutions, e.g.: serum, showed a large non-specific signal. Modifying the support on which the antibodies are attached improved the sensor's stability in serum by a factor of 5. To achieve this non-specific binding (NSB) reduction, different polysaccharides, biocompatible polymers and short chain thiols were investigated.

Global observations of magnetospheric high‐m poloidal waves during the 22 June 2015 magnetic storm

PubMed Central

Chi, P. J.; Strangeway, R. J.; Russell, C. T.; Slavin, J. A.; Takahashi, K.; Singer, H. J.; Anderson, B. J.; Bromund, K.; Fischer, D.; Kepko, E. L.; Magnes, W.; Nakamura, R.; Plaschke, F.; Torbert, R. B.

2017-01-01

Abstract We report global observations of high‐m poloidal waves during the recovery phase of the 22 June 2015 magnetic storm from a constellation of widely spaced satellites of five missions including Magnetospheric Multiscale (MMS), Van Allen Probes, Time History of Events and Macroscale Interactions during Substorm (THEMIS), Cluster, and Geostationary Operational Environmental Satellites (GOES). The combined observations demonstrate the global spatial extent of storm time poloidal waves. MMS observations confirm high azimuthal wave numbers (m ~ 100). Mode identification indicates the waves are associated with the second harmonic of field line resonances. The wave frequencies exhibit a decreasing trend as L increases, distinguishing them from the single‐frequency global poloidal modes normally observed during quiet times. Detailed examination of the instantaneous frequency reveals discrete spatial structures with step‐like frequency changes along L. Each discrete L shell has a steady wave frequency and spans about 1 R E, suggesting that there exist a discrete number of drift‐bounce resonance regions across L shells during storm times. PMID:28713180

Top-antitop production from W^+_L W^-_L and Z_L Z_L scattering under a strongly interacting symmetry-breaking sector

NASA Astrophysics Data System (ADS)

Castillo, Andrés; Delgado, Rafael L.; Dobado, Antonio; Llanes-Estrada, Felipe J.

2017-07-01

By considering a non-linear electroweak chiral Lagrangian, including the Higgs, coupled to heavy quarks, and the equivalence theorem, we compute the one-loop scattering amplitudes W^+W^-→ t\\bar{t}, ZZ→ t\\bar{t} and hh→ t\\bar{t} (in the regime M_t^2/v^2≪ √{s}M_t/v^2≪ s/v^2 and to NLO in the effective theory). We calculate the scalar partial-wave helicity amplitudes which allow us to check unitarity at the perturbative level in both M_t/v and s/ v. As with growing energy perturbative unitarity deteriorates, we also introduce a new unitarization method with the right analytical behavior on the complex s-plane and that can support poles on the second Riemann sheet to describe resonances in terms of the Lagrangian couplings. Thus we have achieved a consistent phenomenological description of any resonant t\\bar{t} production that may be enhanced by a possible strongly interacting electroweak symmetry breaking sector.

Observations of magnetospheric ionization enhancements using upper-hybrid resonance noise band data from the RAE-1 satellite

NASA Technical Reports Server (NTRS)

Mosier, S. R.

1975-01-01

Noise bands associated with the upper-hybrid resonance were used to provide direct evidence for the existence of regions of enhanced density in the equatorial magnetosphere near L = 2. Density enhancements ranging from several percent to as high as 45 percent are observed with radial dimensions of several hundred kilometers. The enhancement characteristics strongly suggest their identification as magnetospheric whistler ducts.

Central diffractive resonance production at the LHC

NASA Astrophysics Data System (ADS)

Fiore, Roberto; Jenkovszky, Laszlo; Schicker, Rainer

2016-07-01

Central production of resonances resulting from the scattering of Pomerons in the central rapidity region of proton-proton scattering is studied. Estimates for relevant cross sections are presented. L.J. gratefully acknowledges an EMMI visiting Professorship at the University of Heidelberg for completion of this work. He is grateful to the organizers of this meeting for their hospitality and support. His work was supported also by DOMUS, Hungarian Academy of Sciences

Defense AT&L Magazine. Volume 43, Number 5. September-October 2014

DTIC Science & Technology

2014-10-01

Air Warfare Center Weapons Atlas V launches third Advanced Extremely High Frequency Satellite for the U.S. Air Force in September 2013. United...nanoparticles have been extensively studied for their unique optical properties which arise from localized surface plasmon resonance (LSPR). This... resonance results in a very strong attenuation of light in the visible and near-infrared regions due to the strong enhancement of the local electric

Monolithic Micromachined Quartz Resonator based Infrared Focal Plane Arrays

DTIC Science & Technology

2012-05-05

following categories: PaperReceived Ping Kao, Srinivas Tadigadapa. Micromachined quartz resonator based infrared detector array, Sensors and...0. doi: 10.1088/0957-0233/20/12/124007 2012/05/08 19:47:37 6 S Tadigadapa, K Mateti. Piezoelectric MEMS sensors : state-of-the-art and perspectives...Ping Kao, David L. Allara, Srinivas Tadigadapa. Study of Adsorption of Globular Proteins on Hydrophobic Surfaces, IEEE Sensors Journal, (11 2011): 0

Plasmonic Metasurfaces Based on Nanopin-Cavity Resonator for Quantitative Colorimetric Ricin Sensing.

PubMed

Fan, Jiao-Rong; Zhu, Jia; Wu, Wen-Gang; Huang, Yun

2017-01-01

In view of the toxic potential of a bioweapon threat, rapid visual recognition and sensing of ricin has been of considerable interest while remaining a challenging task up to date. In this study, a gold nanopin-based colorimetric sensor is developed realizing a multicolor variation for ricin qualitative recognition and analysis. It is revealed that such plasmonic metasurfaces based on nanopin-cavity resonator exhibit reflective color appearance, due to the excitation of standing-wave resonances of narrow bandwidth in visible region. This clear color variation is a consequence of the reflective color mixing defined by different resonant wavelengths. In addition, the colored metasurfaces appear sharp color difference in a narrow refractive index range, which makes them especially well-suited for sensing applications. Therefore, this antibody-functionalized nanopin-cavity biosensor features high sensitivity and fast response, allowing for visual quantitative ricin detection within the range of 10-120 ng mL -1 (0.15 × 10 -9 -1.8 × 10 -9 m), a limit of detection of 10 ng mL -1 , and the typical measurement time of less than 10 min. The on-chip integration of such nanopin metasurfaces to portable colorimetric microfluidic device may be envisaged for the quantitative studies of a variety of biochemical molecules. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Modeling scattering enhancements at isolated resonances using energy conservation, reciprocity, symmetry, and the optical theorem

NASA Astrophysics Data System (ADS)

Marston, Philip L.; Osterhoudt, Curtis F.

2003-04-01

Sound scattered by some objects in water exhibits isolated narrow resonances that are sufficiently large in amplitude to dominate the low-frequency scattering. Examples include the quadrupole mode of thin spherical shells and of solid plastic spheres [B. T. Hefner and P. L. Marston, J. Acoust. Soc. Am. 107, 1930-1936 (2000)] and organ-pipe modes of water-filled pipes [C. F. Osterhoudt and P. L. Marston, J. Acoust. Soc. Am. 110, 2773 (2001)]. This presentation concerns simple methods for approximating the scattering. In the case of spheres, ray theory for the backscattering reduces to a simple form for high-Q modes: Eq. (58) of Marston [J. Acoust. Soc. Am. 83, 25-37 (1988)]. This result gives the backscattering form function at resonance (in the usual normalization) to have the magnitude 2(2n+1)/ka. Here n is the partial wave index associated with the mode of the sphere and ka is the product of the wave number and the sphere radius. This result may also be derived directly from energy conservation and the optical theorem. Scattering amplitudes associated with high-Q organ pipe resonances of open cylindrical pipes are also derived here by a related method using the energy conservation, reciprocity, symmetry, and the optical theorem.

Attenuation process of the longitudinal phonon mode in a TeO2 crystal in the 20-GHz range

NASA Astrophysics Data System (ADS)

Ohno, S.; Sonehara, T.; Tatsu, E.; Koreeda, A.; Saikan, S.

2017-06-01

We experimentally investigated the hypersonic attenuation process of a longitudinal mode (L-mode) sound wave in TeO2 from room temperature to a lower temperature using Brillouin scattering and impulsive stimulated thermal scattering (ISTS) measurements. For precise measurement of the Brillouin linewidth at low temperatures, whereby the mean free path of the phonon becomes longer than the sample length, it is indispensable that the phonon should propagate along the phonon-resonance direction. To figure out the suitable direction, we defined two indices characterizing a degree of phonon divergence and a purity of propagation direction. The best direction that we found from these indices is [110] direction in TeO2, and it was used to discuss the temperature and frequency dependences of Brillouin spectra. We extracted the temperature dependence of the attenuation rate of T4 from the modulated Brillouin spectra due to the phonon resonance below Debye temperature. The frequency dependence ω1 of the hypersonic attenuation was also estimated from the polarization dependence of the Brillouin linewidth. Theoretically, it predicted that the L-mode phonon attenuation at low temperatures in TeO2 is a result of Herring's process, which shows the attenuation behavior of ω2T3 . The ω1T4 dependence is not allowed in Herring's process but is allowed by the L +L →L process, which has been considered to be forbidden so far. We evaluated the thermal phonon lifetime using ISTS and established that it was finite even at 20 K, thereby allowing the L +L →L process. Therefore, we conclude that the L +L →L process dominates the attenuation of an L-mode phonon in TeO2 in the low-temperature region.

Stereochemistry and solvent role in protein folding: nuclear magnetic resonance and molecular dynamics studies of poly-L and alternating-L,D homopolypeptides in dimethyl sulfoxide.

PubMed

Srivastava, Kinshuk Raj; Kumar, Anil; Goyal, Bhupesh; Durani, Susheel

2011-05-26

The competing interactions folding and unfolding protein structure remain obscure. Using homopolypeptides, we ask if poly-L structure may have a role. We mutate the structure to alternating-L,D stereochemistry and substitute water as the fold-promoting solvent with methanol and dimethyl sulfoxide (DMSO) as the fold-denaturing solvents. Circular dichroism and molecular dynamics established previously that, while both isomers were folded in water, the poly-L isomer was unfolded and alternating-L,D isomer folded in methanol. Nuclear magnetic resonance and molecular dynamics establish now that both isomers are unfolded in DMSO. We calculated energetics of folding-unfolding equilibrium with water and methanol as solvents. We have now calculated interactions of unfolded polypeptide structures with DMSO as solvent. Methanol was found to unfold and water fold poly-L structure as a dielectric. DMSO has now been found to unfold both poly-L and alternating-L,D structures by strong solvation of peptides to disrupt their hydrogen bonds. Accordingly, we propose that while linked peptides fold protein structure with hydrogen bonds they unfold the structure electrostatically due to the stereochemical effect of the poly-L structure. Protein folding to ordering of peptide hydrogen bonds with water as canonical solvent may thus involve two specific and independent solvent effects-one, strong screening of electrostatics of poly-L linked peptides, and two, weak dipolar solvation of peptides. Correspondingly, protein denaturation may involve two independent solvent effects-one, weak dielectric to unfold poly-L structure electrostatically, and two, strong polarity to disrupt peptide hydrogen bonds by solvation of peptides.

Optimal gadolinium dose level for magnetic resonance imaging (MRI) contrast enhancement of U87-derived tumors in athymic nude rats for the assessment of photodynamic therapy

NASA Astrophysics Data System (ADS)

Cross, Nathan; Varghai, Davood; Flask, Chris A.; Feyes, Denise K.; Oleinick, Nancy L.; Dean, David

2009-02-01

This study aims to determine the effect of varying gadopentetate dimeglumine (Gd-DTPA) dose on Dynamic Contrast Enhanced-Magnetic Resonance Imaging (DCE-MRI) tracking of brain tumor photodynamic therapy (PDT) outcome. Methods: We injected 2.5 x 105 U87 cells (derived from human malignant glioma) into the brains of six athymic nude rats. After 9, 12, and 13 days DCE-MRI images were acquired on a 9.4 T micro-MRI scanner before and after administration of 100, 150, or 200 μL of Gd-DTPA. Results: Tumor region normalized DCE-MRI scan enhancement at peak was: 1.217 over baseline (0.018 Standard Error [SE]) at the 100 μL dose, 1.339 (0.013 SE) at the 150 μL dose, and 1.287 (0.014 SE) at the 200 μL dose. DCE-MRI peak tumor enhancement at the 150 μL dose was significantly greater than both the 100 μL dose (p < 3.323E-08) and 200 μL dose (p < 0.0007396). Discussion: In this preliminary study, the 150 μL Gd-DTPA dose provided the greatest T1 weighted contrast enhancement, while minimizing negative T2* effects, in DCE-MRI scans of U87-derived tumors. Maximizing Gd-DTPA enhancement in DCE-MRI scans may assist development of a clinically robust (i.e., unambiguous) technique for PDT outcome assessment.

Metabolite profiling of Listeria innocua for unravelling the inactivation mechanism of electrolysed water by nuclear magnetic resonance spectroscopy.

PubMed

Liu, Qin; Wu, Ji'en; Lim, Zhi Yang; Lai, Shaojuan; Lee, Norman; Yang, Hongshun

2018-04-20

Bactericidal effects of low concentration electrolysed water (LcEW) on microorganisms are previously well reported; however, the inactivation mechanism of EW is not understood. The lethal and sublethal injuries of L. monocytogenes and L. innocua by EW treatments were determined and the metabolic profile changes for L. innocua were characterised using nuclear magnetic resonance (NMR). Microbial metabolomics approach combined with multivariate data analyses was used to interpret the cellular chemical fingerprints of L. innocua. The relative amount of intracellular reactive oxygen species (ROS) was assayed using 2',7-dichlorodihydrofluorescein diacetate (H 2 DCFDA). The results showed that the proportion of the sublethally injured microbial cells L. monocytogenes and L. innocua increased from 40% to 70% and from 35% to 65%, respectively, when the free available chlorine (FAC) of LcEW increased from 2 to 8 mg/L. Overall, 36 low-molecular-weight metabolic compounds in L. innocua extracts were characterised by NMR spectroscopy. EW perturbation resulted in a drastic and multitude disruption across a wide range of biochemical process including peptidoglycan synthesis, nucleotides biosynthesis and amino acid metabolism. Elevated levels of α-ketoglutarate and succinate implicated the enhanced glutamate decarboxylase (GAD) system and γ-aminobutyric acid (GABA) shunt for the protection against oxidative stress. These findings provided the comprehensive insights into the metabolic response of Listeria to EW oxidative stress and can serve as a basis for better utilisation for sanitisation. Copyright © 2018 Elsevier B.V. All rights reserved.

Magnetic resonance imaging and dual energy X-ray absorptiometry of the lumbar spine in professional wrestlers and untrained men.

PubMed

Hu, M; Sheng, J; Kang, Z; Zou, L; Guo, J; Sun, P

2014-08-01

The aim of this study was to examine the relation between bone marrow adipose tissue (BMAT) and bone mineral density (BMD) of lumbar spine in male professional wrestlers and healthy untrained men. A total of 14 wrestlers (22.9±3.4 years) and 11 controls (24.4±1.6 years) were studied cross-sectionally. Body composition and BMD were measured by dual-energy X-ray absorptiometry. Magnetic resonance imaging of the lumbar spine was examined in a sagittal T1-weighted (T1-w) spin-echo (SE) sequence. The averaged bone marrow signal intensity (SI) of L2-L4 was related to the signal of an adjacent nondegenerative disk. Mean SI of T1-w SE in wrestlers was lower than controls (P=0.001), indicating L2-L4 BMAT in wrestlers was lower compared to controls. L2-L4 BMD in wrestlers was higher than controls (P<0.001). In the total subject population, L2-L4 BMD was inversely correlated with mean SI of T1-w SE (r=-0.62, P=0.001). This association remained strong after adjusting for body mass and whole lean mass, but became weaker after adjusting for whole body or trunk fat percentage. The inverse relationship between BMAT and BMD was confirmed in this relatively small subject sample with narrow age range, which implies that exercise training is an important determinant of this association.

Automatic loudness control in short-form content for broadcasting.

PubMed

Pires, Leandro da S; Vieira, Maurílio N; Yehia, Hani C

2017-03-01

During the early years of the International Telecommunication Union (ITU) loudness calculation standard for sound broadcasting [ITU-R (2006), Rec. BS Series, 1770], the need for additional loudness descriptors to evaluate short-form content, such as commercials and live inserts, was identified. This work proposes a loudness control scheme to prevent loudness jumps, which can bother audiences. It employs short-form content audio detection and dynamic range processing methods for the maximum loudness level criteria. Detection is achieved by combining principal component analysis for dimensionality reduction and support vector machines for binary classification. Subsequent processing is based on short-term loudness integrators and Hilbert transformers. The performance was assessed using quality classification metrics and demonstrated through a loudness control example.

Performance Evaluation and Adaptability Research of Flowing Gel System Prepared with Re-injected Waste Water

NASA Astrophysics Data System (ADS)

Shi, Lei; You, Jing; Liu, Na; Liu, Xinmin; Wang, Zhiqiang; Zhang, Tiantian; Gu, Yi; Guo, Suzhen; Gao, Shanshan

2017-12-01

The crosslinking intensity and stability of flowing gel system prepared with re-injected waste water are seriously affected as the high salinity waste water contains a high concentration of Na+, Fe2+, S2-, Ca2+, etc. The influence of various ions on the flowing gel system can be reduced by increasing polymer concentration, adding new ferric ion stabilizing agent (MQ) and calcium ion eliminating agent (CW). The technique of profile controlling and oil-displacing is carried out in Chanan multi-purpose station, Chabei multi-purpose station and Chayi multi-purpose station of Huabei Oilfield. The flowing gel system is injected from 10 downflow wells and the 15 offsetting production wells have increased the yield by 1770 tons.

[Hölderlin--or the question of the meaning of psychosis].

PubMed

Gonther, U; Schlimme, J E

2009-03-01

Friedrich Hölderlin (1770-1843) is one of the most important German poets. Actual research into his life and work has shown new aspects in his thinking concerning questions about subjectivity, sense of life and psychosis. We follow these lines using a hermeneutical method. In his late poems the experience of schizophrenic alienation appears metaphorically speaking like an ebbing of a former plenitude of meanings or as if he were decentered from his own life. Hölderlin names it an "uninvolved" view onto the ordinary life. Hölderlin invites and enables us via his offer for an innerperspective understanding of the schizophrenic experience of alienation to deal fairly and respectfully with schizophrenic patients as if we were "alienists" (E. Straus).

Procalcitonin as a marker of serious bacterial infections in febrile children younger than 3 years old.

PubMed

Mahajan, Prashant; Grzybowski, Mary; Chen, Xinguang; Kannikeswaran, Nirupama; Stanley, Rachel; Singal, Bonita; Hoyle, John; Borgialli, Dominic; Duffy, Elizabeth; Kuppermann, Nathan

2014-02-01

There is no perfectly sensitive or specific test for identifying young, febrile infants and children with occult serious bacterial infections (SBIs). Studies of procalcitonin (PCT), a 116-amino-acid precursor of the hormone calcitonin, have demonstrated its potential as an acute-phase biomarker for SBI. The objective of this study was to compare performance of serum PCT with traditional screening tests for detecting SBIs in young febrile infants and children. This was a prospective, multicenter study on a convenience sample from May 2004 to December 2005. The study was conducted in four emergency departments (EDs): one pediatric ED and three EDs with pediatric units, all with academic faculty on staff. A total of 226 febrile children 36 months old or younger who presented to the four participating EDs and were evaluated for SBI by blood, urine, and/or cerebral spinal fluid (CSF) cultures were included. The test characteristics (with 95% confidence intervals [CIs]) of the white blood cell (WBC) counts including neutrophil and band counts were compared with PCT for identifying SBI. Thirty children had SBIs (13.3%, 95% CI = 8.85 to 17.70). Four (13.3%) had bacteremia (including one with meningitis), 18 (60.0%) had urinary tract infections (UTIs), and eight (26.6%) had pneumonia. Children with SBIs had higher WBC counts (18.6 × 10(9)  ± 8.6 × 10(9) cells/L vs. 11.5 × 10(9)  ± 5.3 × 10(9) cells/L, p < 0.001), higher absolute neutrophil counts (ANCs; 10.6 × 10(9)  ± 6.7 × 10(9) cells/L vs. 5.6 × 10(9)  ± 3.8 × 10(9) cells/L, p = 0.009), higher absolute band counts (0.90 × 10(9)  ± 1.1 × 10(9) cells/L vs. 0.35 × 10(9)  ± 0.6 × 10(9) cells/L, p = 0.009), and higher PCT levels (2.9 ± 5.6 ng/mL vs. 0.4 ± 0.8 ng/mL, p = 0.021) than those without SBIs. In a multivariable logistic regression analysis, the absolute band count and PCT were the two screening tests independently associated with SBI, although the area under the receiver operating characteristic (ROC) curve for PCT was the largest (0.80, 95% CI = 0.71 to 0.89). Procalcitonin is a more accurate biomarker than traditional screening tests for identifying young febrile infants and children with serious SBIs. Further study on a larger cohort of young febrile children is required to definitively determine the benefit of PCT over traditional laboratory screening tests for SBIs. © 2014 by the Society for Academic Emergency Medicine.

Porous silicon micro-resonator implemented by standard photolithography process for sensing application

NASA Astrophysics Data System (ADS)

Girault, P.; Azuelos, P.; Lorrain, N.; Poffo, L.; Lemaitre, J.; Pirasteh, P.; Hardy, I.; Thual, M.; Guendouz, M.; Charrier, J.

2017-10-01

A micro-resonator based on porous silicon ridge waveguides is implemented by a large scale standard photolithography process to obtain a low cost and sensitive sensor based on volume detection principle instead of the evanescent one usually used. The porous nature of the ridge waveguides allows the target molecules to be infiltrated in the core and to be detected by direct interaction with the propagated light. Racetrack resonator with radius of 100 μm and a coupling length of 70 μm is optically characterized for the volume detection of different concentrations of glucose. A high sensitivity of 560 nm/RIU is reached with only one micro-resonator and a limit of detection of 8.10-5 RIU, equivalent to a glucose concentration of 0.7 g/L, is obtained.

Subdominant Dark Matter sterile neutrino resonant production in the light of PLANCK

DOE Office of Scientific and Technical Information (OSTI.GOV)

Popa, L.A.; Tonoiu, D., E-mail: lpopa@spacescience.ro, E-mail: tonoiud@spacescience.ro

2015-09-01

Few independent detections of a weak X-ray line at an energy of ∼ 3.5 keV seen toward a number of astrophysical sites have been reported. If this signal will be confirmed to be the signature of decaying DM sterile neutrino with a mass of ∼ 7.1 keV, then the cosmological observables should be consistent with its properties. In this paper we make a coupled treatment of the weak decoupling, primordial nucleosynthesis and photon decoupling epochs in the sterile neutrino resonant production scenario, including the extra radiation energy density via N{sub eff}. We compute the radiation and matter perturbations including the full resonancemore » sweep solution for ν{sub α}/ν-bar {sub α} → ν{sub s} flavor conversion in the expanding Universe.We show that the cosmological measurements are in agreement with subdominant Dark Matter sterile neutrino resonant production with following parameters (errors at 95% CL): mass m{sub ν{sub s}}=6.08 ± 3.22 keV, mixing angle sin{sup 2} 2θ < 5.61 × 10{sup −10}, lepton number per flavor L{sub 4} = 1.23 ± 0.04 (L{sub 4} ≡ 10{sup 4} L{sub ν{sub a}}) and sterile neutrino mass fraction f{sub ν{sub s}}< 0.078.Our results are in good agreement with the sterile neutrino resonant production parameters inferred in ref. [1] from the linear large scale structure constraints to produce full Dark Matter density.« less

Effective Power-Law Dependence of Lyapunov Exponents on the Central Mass in Galaxies

NASA Technical Reports Server (NTRS)

Delis, N.; Efthymiopoulos, C.; Kalapotharakos, C.

2015-01-01

Using both numerical and analytical approaches, we demonstrate the existence of an effective power-law relation L alpha m(sup p) between themean Lyapunov exponent L of stellar orbits chaotically scattered by a supermassive black hole (BH) in the centre of a galaxy and the mass parameter m, i.e. ratio of the mass of the BH over the mass of the galaxy. The exponent p is found numerically to obtain values in the range p approximately equals 0.3-0.5. We propose a theoretical interpretation of these exponents, based on estimates of local 'stretching numbers', i.e. local Lyapunov exponents at successive transits of the orbits through the BH's sphere of influence. We thus predict p = 2/3 - q with q approximately equaling 0.1-0.2. Our basic model refers to elliptical galaxy models with a central core. However, we find numerically that an effective power-law scaling of L with m holds also in models with central cusp, beyond a mass scale up to which chaos is dominated by the influence of the cusp itself. We finally show numerically that an analogous law exists also in disc galaxies with rotating bars. In the latter case, chaotic scattering by the BH affects mainly populations of thick tube-like orbits surrounding some low-order branches of the x(sub 1) family of periodic orbits, as well as its bifurcations at low-order resonances, mainly the inner Lindblad resonance and the 4/1 resonance. Implications of the correlations between L and m to determining the rate of secular evolution of galaxies are discussed.

Effect of injection rate on contrast-enhanced MR angiography image quality: Modulation transfer function analysis.

PubMed

Clark, Toshimasa J; Wilson, Gregory J; Maki, Jeffrey H

2017-07-01

Contrast-enhanced (CE)-MRA optimization involves interactions of sequence duration, bolus timing, contrast recirculation, and both R 1 relaxivity and R2*-related reduction of signal. Prior data suggest superior image quality with slower gadolinium injection rates than typically used. A computer-based model of CE-MRA was developed, with contrast injection, physiologic, and image acquisition parameters varied over a wide gamut. Gadolinium concentration was derived using Verhoeven's model with recirculation, R 1 and R2* calculated at each time point, and modulation transfer curves used to determine injection rates, resulting in optimal resolution and image contrast for renal and carotid artery CE-MRA. Validation was via a vessel stenosis phantom and example patients who underwent carotid CE-MRA with low effective injection rates. Optimal resolution for renal and carotid CE-MRA is achieved with injection rates between 0.5 to 0.9 mL/s and 0.2 to 0.3 mL/s, respectively, dependent on contrast volume. Optimal image contrast requires slightly faster injection rates. Expected signal-to-noise ratio varies with both contrast volume and cardiac output. Simulated vessel phantom and clinical carotid CE-MRA exams at an effective contrast injection rate of 0.4 to 0.5 mL/s demonstrate increased resolution. Optimal image resolution is achieved at intuitively low, effective injection rates (0.2-0.9 mL/s, dependent on imaging parameters and contrast injection volume). Magn Reson Med 78:357-369, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

Silicon nano-membrane based photonic crystal microcavities for high sensitivity bio-sensing.

PubMed

Lai, Wei-Cheng; Chakravarty, Swapnajit; Zou, Yi; Chen, Ray T

2012-04-01

We experimentally demonstrated photonic crystal microcavity based resonant sensors coupled to photonic crystal waveguides in silicon nano-membrane on insulator for chemical and bio-sensing. Linear L-type microcavities are considered. In contrast to cavities with small mode volumes, but low quality factors for bio-sensing, we showed increasing the length of the microcavity enhances the quality factor of the resonance by an order of magnitude and increases the resonance wavelength shift while retaining compact device characteristics. Q~26760 and sensitivity down to 15 ng/ml and ~110 pg/mm2 in bio-sensing was experimentally demonstrated on silicon-on-insulator devices.

l-Theanine and caffeine improve target-specific attention to visual stimuli by decreasing mind wandering: a human functional magnetic resonance imaging study.

PubMed

Kahathuduwa, Chanaka N; Dhanasekara, Chathurika S; Chin, Shao-Hua; Davis, Tyler; Weerasinghe, Vajira S; Dassanayake, Tharaka L; Binks, Martin

2018-01-01

Oral intake of l-theanine and caffeine supplements is known to be associated with faster stimulus discrimination, possibly via improving attention to stimuli. We hypothesized that l-theanine and caffeine may be bringing about this beneficial effect by increasing attention-related neural resource allocation to target stimuli and decreasing deviation of neural resources to distractors. We used functional magnetic resonance imaging (fMRI) to test this hypothesis. Solutions of 200mg of l-theanine, 160mg of caffeine, their combination, or the vehicle (distilled water; placebo) were administered in a randomized 4-way crossover design to 9 healthy adult men. Sixty minutes after administration, a 20-minute fMRI scan was performed while the subjects performed a visual color stimulus discrimination task. l-Theanine and l-theanine-caffeine combination resulted in faster responses to targets compared with placebo (∆=27.8milliseconds, P=.018 and ∆=26.7milliseconds, P=.037, respectively). l-Theanine was associated with decreased fMRI responses to distractor stimuli in brain regions that regulate visual attention, suggesting that l-theanine may be decreasing neural resource allocation to process distractors, thus allowing to attend to targets more efficiently. l-Theanine-caffeine combination was associated with decreased fMRI responses to target stimuli as compared with distractors in several brain regions that typically show increased activation during mind wandering. Factorial analysis suggested that l-theanine and caffeine seem to have a synergistic action in decreasing mind wandering. Therefore, our hypothesis is that l-theanine and caffeine may be decreasing deviation of attention to distractors (including mind wandering); thus, enhancing attention to target stimuli was confirmed. Copyright © 2017 Elsevier Inc. All rights reserved.

A novel method for resonant inelastic soft X-ray scattering via photoelectron spectroscopy detection

DOE PAGES

Dakovski, Georgi L.; Lin, Ming-Fu; Damiani, Daniel S.; ...

2017-10-05

A method for measuring resonant inelastic X-ray scattering based on the conversion of X-ray photons into photoelectrons is presented in this paper. The setup is compact, relies on commercially available detectors, and offers significant flexibility. Finally, this method is demonstrated at the Linac Coherent Light Source with ~0.5 eV resolution at the cobalt L 3-edge, with signal rates comparable with traditional grating spectrometers.

New Synthetic Approaches to TAT

DTIC Science & Technology

1990-03-30

stabilized externally by resonance stabilization of electron withdrawing substituents placed on all four Nitrogen aL,.ms (T,- N -:, ...7; 4- N -NO2 HMX, etc...or internally by ring carbonyl groups adja- cent to the ring- N -atoms (amide resonance). 1. Cyclization experiments on methylene-bisacetamide (MBA4...more, the high instability of the desired 8-membered [8]ane- N 4 system, and the difficulty to apply proper cond’tion-. what the final products can

Study of Electromagnetic Wave Absorption Properties of Carbon Nanotubes-Based Composites

DTIC Science & Technology

2012-11-29

Publications: [1]. G. L. Zhao, Z. Ye, Z. Li, J. A. Roberts, "New carbon nanotube-epoxy composite for dampening microwave cavity resonance", IEEE Xplore ...Nanotechnology ( IEEE - NANO), 2012 12th IEEE Conference on 20-23 Aug. 2012. [2]. Z. Li, G. L. Zhao, P. Zhang, S. Guo, J. Tang, " Thermoelectric

Electron Transport in Graphene From a Diffusion-Drift Perspective

DTIC Science & Technology

2010-02-24

Tung, M.E. Schwartz, M. Takita, Y.-J. Wang, P. Kim, and H.L. Stormer , “Cyclotron resonance in bilayer graphene,” Phys. Rev. Lett. 100, 087403 (2008...Dec. 2004. [3] K. I. Bolotin, K. J. Sikes, Z. Jiang, M. Klima, G. Fudenberg, J. Hone, P. Kim, and H. L. Stormer , “Ultrahigh electron mobility in

Use of NMR spectroscopy and magnetic resonance imaging for discriminating Juglans nigra L. seeds

Treesearch

John A. Vozzo; J.M. Halloin; T.G. Cooper; E.J. Potechen

1996-01-01

Black walnut (JuglamnigraL.) seeds are large and require stratification for germination. However, many seeds fail to germinate following stratification. Radiography can be used to select empty seeds, but cannot determine which full seeds will germinate. The objective of this study was to determine if any discrimination could bc achieved through use...

A Glow Discharge Ion Source with Fourier Transform Ion Cyclotron Resonance Mass Spectrometric Detection

DTIC Science & Technology

1991-05-10

Hall, D . Mikrochim. Acta 1987, 1, 275. 26. Harrison, W.W.; Bentz , B.L. Prog. Analyt. Spectrosc. 1988, L19 53. 27. Harrison, W.W.; Barshick, C.M...Innovation, and Applications. ACS Symp. Series; Buchanan, M.V., Ed.; American Chemical Society: Washington, 1987; 359, p 1. 3. Wilkins, C.L.; Chowdhury, A.K...J.L. In Gas Phase Ion CheMistry; Bowers, M.T., Ed.; Academic: New York, 1984; Vol. 3, p 41. 6. Dunbar, R.C. In Gas Phase Ion Chemistry; Bowvers, M.T

Measuring Physical Properties of Neuronal and Glial Cells with Resonant Microsensors

PubMed Central

2015-01-01

Microelectromechanical systems (MEMS) resonant sensors provide a high degree of accuracy for measuring the physical properties of chemical and biological samples. These sensors enable the investigation of cellular mass and growth, though previous sensor designs have been limited to the study of homogeneous cell populations. Population heterogeneity, as is generally encountered in primary cultures, reduces measurement yield and limits the efficacy of sensor mass measurements. This paper presents a MEMS resonant pedestal sensor array fabricated over through-wafer pores compatible with vertical flow fields to increase measurement versatility (e.g., fluidic manipulation and throughput) and allow for the measurement of heterogeneous cell populations. Overall, the improved sensor increases capture by 100% at a flow rate of 2 μL/min, as characterized through microbead experiments, while maintaining measurement accuracy. Cell mass measurements of primary mouse hippocampal neurons in vitro, in the range of 0.1–0.9 ng, demonstrate the ability to investigate neuronal mass and changes in mass over time. Using an independent measurement of cell volume, we find cell density to be approximately 1.15 g/mL. PMID:24734874

High-resolution infrared spectrum of cyanogen

NASA Astrophysics Data System (ADS)

Maki, Arthur G.

2011-10-01

The high-resolution spectrum of cyanogen ( 14N 12C 12C 14N) has been measured from 500 to 4900 cm -1. For this isotopomer many combination levels with both degenerate fundamentals, ν4 and ν5, have been measured for the first time and the effects of vibrational l-type resonance are observed as well as rotational l-type resonance. The effects of the vibrational resonance coupling ν2 and 2 ν4 have also been studied. The data have been combined with earlier measurements below 500 cm -1 to give a comprehensive catalog of the vibrational energy levels and the rovibrational constants for the normal isotopomer of cyanogen. A comparison of the term value constants for the three major symmetric isotopomers is given and they are compared with a recent ab initio calculation. The present data were combined with earlier work on the two symmetric isotopomers, 13C 214N 2 and 12C 215N 2, to obtain the equilibrium bond lengths, rCC = 138.109(60) pm and rCN = 115.976(40) pm.

{gamma}-ray spectroscopy study of states in {sup 27}Si relevant for the {sup 26}Al{sup m}(p,{gamma}){sup 27}Si reaction in novae and supernovae

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lotay, G.; Woods, P. J.; Seweryniak, D.

2009-11-15

The heavy-ion, fusion-evaporation reaction {sup 12}C({sup 16}O,n) was used to identify {gamma}-decay transitions from excited states in {sup 27}Si above the proton threshold. The precise level energy measurements, J{sup {pi}} assignments, and lifetime measurements of astrophysically important {sup 26}Al{sup m}+p resonances have allowed an evaluation of the {sup 26}Al{sup m}(p,{gamma}){sup 27}Si reaction rate. An l{sub p}=0 resonance has been newly identified at a center-of-mass energy in the {sup 26}Al{sup m}+p system of 146.3(3) keV and is expected to dominate the rate for low stellar temperatures. In addition, an l{sub p}=1 resonance has been identified at 378.3(30) keV and is likelymore » to dominate the rate at high astrophysical temperatures, such as those found in oxygen-neon novae and core-collapse supernovae.« less

Search for tb resonances in proton-proton collisions at √s=7 TeV with the ATLAS detector.

PubMed

Aad, G; Abbott, B; Abdallah, J; Abdel Khalek, S; Abdelalim, A A; Abdesselam, A; Abdinov, O; Abi, B; Abolins, M; Abouzeid, O S; Abramowicz, H; Abreu, H; Acerbi, E; Acharya, B S; Adamczyk, L; Adams, D L; Addy, T N; Adelman, J; Aderholz, M; Adomeit, S; Adragna, P; Adye, T; Aefsky, S; Aguilar-Saavedra, J A; Aharrouche, M; Ahlen, S P; Ahles, F; Ahmad, A; Ahsan, M; Aielli, G; Akdogan, T; Akesson, T P A; Akimoto, G; Akimov, A V; Akiyama, A; Alam, M S; Alam, M A; Albert, J; Albrand, S; Aleksa, M; Aleksandrov, I N; Alessandria, F; Alexa, C; Alexander, G; Alexandre, G; Alexopoulos, T; Alhroob, M; Aliev, M; Alimonti, G; Alison, J; Aliyev, M; Allbrooke, B M M; Allport, P P; Allwood-Spiers, S E; Almond, J; Aloisio, A; Alon, R; Alonso, A; Alvarez Gonzalez, B; Alviggi, M G; Amako, K; Amaral, P; Amelung, C; Ammosov, V V; Amorim, A; Amorós, G; Amram, N; Anastopoulos, C; Ancu, L S; Andari, N; Andeen, T; Anders, C F; Anders, G; Anderson, K J; Andreazza, A; Andrei, V; Andrieux, M-L; Anduaga, X S; Angerami, A; Anghinolfi, F; Anisenkov, A; Anjos, N; Annovi, A; Antonaki, A; Antonelli, M; Antonov, A; Antos, J; Anulli, F; Aoun, S; Aperio Bella, L; Apolle, R; Arabidze, G; Aracena, I; Arai, Y; Arce, A T H; Arfaoui, S; Arguin, J-F; Arik, E; Arik, M; Armbruster, A J; Arnaez, O; Arnal, V; Arnault, C; Artamonov, A; Artoni, G; Arutinov, D; Asai, S; Asfandiyarov, R; Ask, S; Asman, B; Asquith, L; Assamagan, K; Astbury, A; Aubert, B; Auge, E; Augsten, K; Aurousseau, M; Avolio, G; Avramidou, R; Axen, D; Ay, C; Azuelos, G; Azuma, Y; Baak, M A; Baccaglioni, G; Bacci, C; Bach, A M; Bachacou, H; Bachas, K; Backes, M; Backhaus, M; Badescu, E; Bagnaia, P; Bahinipati, S; Bai, Y; Bailey, D C; Bain, T; Baines, J T; Baker, O K; Baker, M D; Baker, S; Banas, E; Banerjee, P; Banerjee, Sw; Banfi, D; Bangert, A; Bansal, V; Bansil, H S; Barak, L; Baranov, S P; Barashkou, A; Barbaro Galtieri, A; Barber, T; Barberio, E L; Barberis, D; Barbero, M; Bardin, D Y; Barillari, T; Barisonzi, M; Barklow, T; Barlow, N; Barnett, B M; 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Bethke, S; Bhimji, W; Bianchi, R M; Bianco, M; Biebel, O; Bieniek, S P; Bierwagen, K; Biesiada, J; Biglietti, M; Bilokon, H; Bindi, M; Binet, S; Bingul, A; Bini, C; Biscarat, C; Bitenc, U; Black, K M; Blair, R E; Blanchard, J-B; Blanchot, G; Blazek, T; Blocker, C; Blocki, J; Blondel, A; Blum, W; Blumenschein, U; Bobbink, G J; Bobrovnikov, V B; Bocchetta, S S; Bocci, A; Boddy, C R; Boehler, M; Boek, J; Boelaert, N; Bogaerts, J A; Bogdanchikov, A; Bogouch, A; Bohm, C; Bohm, J; Boisvert, V; Bold, T; Boldea, V; Bolnet, N M; Bomben, M; Bona, M; Bondarenko, V G; Bondioli, M; Boonekamp, M; Booth, C N; Bordoni, S; Borer, C; Borisov, A; Borissov, G; Borjanovic, I; Borri, M; Borroni, S; Bortolotto, V; Bos, K; Boscherini, D; Bosman, M; Boterenbrood, H; Botterill, D; Bouchami, J; Boudreau, J; Bouhova-Thacker, E V; Boumediene, D; Bourdarios, C; Bousson, N; Boveia, A; Boyd, J; Boyko, I R; Bozhko, N I; Bozovic-Jelisavcic, I; Bracinik, J; Braem, A; Branchini, P; Brandenburg, G W; Brandt, A; Brandt, G; Brandt, O; Bratzler, U; Brau, B; Brau, J E; Braun, H M; Brelier, B; Bremer, J; Brendlinger, K; Brenner, R; Bressler, S; Britton, D; Brochu, F M; Brock, I; Brock, R; Brodbeck, T J; Brodet, E; Broggi, F; Bromberg, C; Bronner, J; Brooijmans, G; Brooks, W K; Brown, G; Brown, H; Bruckman de Renstrom, P A; Bruncko, D; Bruneliere, R; Brunet, S; Bruni, A; Bruni, G; Bruschi, M; Buanes, T; Buat, Q; Bucci, F; Buchanan, J; Buchholz, P; Buckingham, R M; Buckley, A G; Buda, S I; Budagov, I A; Budick, B; Büscher, V; Bugge, L; Bulekov, O; Bundock, A C; Bunse, M; Buran, T; Burckhart, H; Burdin, S; Burgess, T; Burke, S; Busato, E; Bussey, P; Buszello, C P; Butin, F; Butler, B; Butler, J M; Buttar, C M; Butterworth, J M; Buttinger, W; Cabrera Urbán, S; Caforio, D; Cakir, O; Calafiura, P; Calderini, G; Calfayan, P; Calkins, R; Caloba, L P; Caloi, R; Calvet, D; Calvet, S; Camacho Toro, R; Camarri, P; Cambiaghi, M; Cameron, D; Caminada, L M; Campana, S; Campanelli, M; Canale, V; Canelli, F; Canepa, A; Cantero, J; Capasso, L; Capeans Garrido, M D M; Caprini, I; Caprini, M; Capriotti, D; Capua, M; Caputo, R; Cardarelli, R; Carli, T; Carlino, G; Carminati, L; Caron, B; Caron, S; Carquin, E; Carrillo Montoya, G D; Carter, A A; Carter, J R; Carvalho, J; Casadei, D; Casado, M P; Cascella, M; Caso, C; Castaneda Hernandez, A M; Castaneda-Miranda, E; Castillo Gimenez, V; Castro, N F; Cataldi, G; Catastini, P; Catinaccio, A; Catmore, J R; Cattai, A; Cattani, G; Caughron, S; Cauz, D; Cavalleri, P; Cavalli, D; Cavalli-Sforza, M; Cavasinni, V; Ceradini, F; Cerqueira, A S; Cerri, A; Cerrito, L; Cerutti, F; Cetin, S A; Cevenini, F; Chafaq, A; Chakraborty, D; Chalupkova, I; Chan, K; Chapleau, B; Chapman, J D; Chapman, J W; Chareyre, E; Charlton, D G; Chavda, V; Chavez Barajas, C A; Cheatham, S; Chekanov, S; Chekulaev, S V; Chelkov, G A; Chelstowska, M A; Chen, C; Chen, H; Chen, S; Chen, T; Chen, X; Cheng, S; Cheplakov, A; Chepurnov, V F; Cherkaoui El Moursli, R; Chernyatin, V; Cheu, E; Cheung, S L; Chevalier, L; Chiefari, G; Chikovani, L; Childers, J T; Chilingarov, A; Chiodini, G; Chisholm, A S; Chislett, R T; Chizhov, M V; Choudalakis, G; Chouridou, S; Christidi, I A; Christov, A; Chromek-Burckhart, D; Chu, M L; Chudoba, J; Ciapetti, G; Ciftci, A K; Ciftci, R; Cinca, D; Cindro, V; Ciocca, C; Ciocio, A; Cirilli, M; Citterio, M; Ciubancan, M; Clark, A; Clark, P J; Cleland, W; Clemens, J C; Clement, B; Clement, C; Coadou, Y; Cobal, M; Coccaro, A; Cochran, J; Coe, P; Cogan, J G; Coggeshall, J; Cogneras, E; Colas, J; Colijn, A P; Collins, N J; Collins-Tooth, C; Collot, J; Colon, G; Conde Muiño, P; Coniavitis, E; Conidi, M C; Consonni, M; Consonni, S M; Consorti, V; Constantinescu, S; Conta, C; Conti, G; Conventi, F; Cook, J; Cooke, M; Cooper, B D; Cooper-Sarkar, A M; Copic, K; Cornelissen, T; Corradi, M; Corriveau, F; Cortes-Gonzalez, A; Cortiana, G; Costa, G; Costa, M J; Costanzo, D; Costin, T; Côté, D; Courneyea, L; Cowan, G; Cowden, C; Cox, B E; Cranmer, K; Crescioli, F; Cristinziani, M; Crosetti, G; 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2012-08-24

This Letter presents a search for tb resonances in 1.04 fb(-1) of LHC proton-proton collision data collected by the ATLAS detector at a center-of-mass energy of 7 TeV. Events with a lepton, missing transverse momentum, and two jets are selected and the invariant mass of the corresponding final state is reconstructed. The search exploits the shape of the tb invariant mass distribution compared to the expected standard model backgrounds. The model of a right-handed W(R)' with standard model-like couplings is chosen as the benchmark model for this search. No statistically significant excess of events is observed in the data, and upper limits on the cross section times the branching ratio of W(R)' resonances at 95% C.L. lie in the range of 6.1-1.0 pb for W(R)' masses ranging from 0.5 to 2.0 TeV. These limits are translated into a lower bound on the allowed right-handed W(R)' mass, giving m(W(R)'))>1.13 TeV at 95% C.L.

Topography-coupled resonance between Mars normal-modes and the tidal force of the Phobos

NASA Astrophysics Data System (ADS)

Tian, Y.; Zheng, Y.

2016-12-01

Phobos is the largest moon of Mars. The gravity attraction of Phobos to Mars is a periodic force, which may excite seismic waves inside Mars. Since Phobos is below the synchronous orbit, its orbit is continuously decreasing due to the tidal effect. This will result in a monotonic increase in its orbital frequency, which may eventually intrude into the seismic normal-mode frequency range to cause resonance. The objective of this research is to investigate whether such a resonance phenomenon can occur and what the consequence is. As we know, resonance happens when the periodic tidal force has a similar frequency as that of martian normal modes. It can be shown that such a resonance will not occur if Mars is perfectly spherical because the tidal force can only excite modes of the same angular order. For the same angular order, the tidal force frequencies are always smaller than those of the normal modes. However, when we consider the effect of topography of Mars, the resonance can occur because of coupling of normal modes. We use numerical method to calculate when the resonance will occur. We firstly solve for the normal modes of Mars by idealizing it as a solid elastic sphere. At the second step, we calculate the excitation effect of gravitational force from Phobos on each individual normal mode. For example, the gravity tidal force F at L=5, m=5 F55 can excite a normal mode 0S5 which can be coupled to 0T2. The third step is to calculate the frequency that the resonance will happen. For example, when the rotation frequency of Phobos increase to 0.8 mRad/s, the tidal force at L=5, m=5 can reach 4mRad/s which is the eigen-frequency of 0T2. Since we have calculated the coupling factors between each individual mode, the amplitude coefficients can be solved by a linear equation. We can observe a 100 times of amplitude increase of mode 0T2, which convince us the resonance will happen. The resonance may cause large amplitude of ground vibration of Mars. From our calculation, when the resonance happen, the energy dissipation rate will be greatly increased, which will make Phobos falling much faster. Eventually, Phobos will hit Mars in a very short time. Our research may give us a new prospective on early formation of planets.

Lower cerebral blood flow in subjects with Alzheimer's dementia, mild cognitive impairment, and subjective cognitive decline using two-dimensional phase-contrast magnetic resonance imaging.

PubMed

Leijenaar, Jolien F; van Maurik, Ingrid S; Kuijer, Joost P A; van der Flier, Wiesje M; Scheltens, Philip; Barkhof, Frederik; Prins, Niels D

2017-01-01

In this cross-sectional study, we aimed to detect differences in cerebral blood flow (CBF) between subjects with Alzheimer's disease (AD), mild cognitive impairment (MCI), and subjective cognitive decline (SCD), using two-dimensional phase-contrast magnetic resonance imaging. We included 74 AD patients (67 years, 51% female), 36 MCI patients (66 years, 33% female), and 62 patients with SCD (60 years, 32% female) from the Amsterdam Dementia Cohort. Patients with SCD are those who visited the memory clinic with subjective cognitive complaints without objective cognitive impairment. Whole-brain CBF (mL/100 g/min) was calculated using total volume flow measured with two-dimensional phase-contrast magnetic resonance imaging and normalized for brain volume. Mean CBF values (SD) were lower in AD compared to SCD (age and sex adjusted 70 ± 26 vs. 82 ± 24 mL/100 g/min, P  < .05). Mean CBF values of MCI were comparable to AD. Across clinical groups, lower CBF was associated with lower scores on the Mini-Mental State Examination (age and sex adjusted stβ = 0.19 per mL/100 g/min; P  = .02). Lower whole-brain CBF is seen in AD patients compared to SCD patients and is associated with worse cognitive function.

The ATLAS diboson resonance in non-supersymmetric SO(10)

DOE PAGES

Evans, Jason L.; Nagata, Natsumi; Olive, Keith A.; ...

2016-02-18

SO(10) grand uni cation accommodates intermediate gauge symmetries with which gauge coupling uni cation can be realized without supersymmetry. In this paper, we discuss the possibility that a new massive gauge boson associated with an intermediate gauge symmetry explains the excess observed in the diboson resonance search recently reported by the ATLAS experiment. The model we find has two intermediate symmetries, SU(4) C Ⓧ SU(2) L Ⓧ SU(2) R and SU(3) C Ⓧ SU(2) L Ⓧ SU(2)R Ⓧ U(1) B-L, where the latter gauge group is broken at the TeV scale. This model achieves gauge coupling uni cation with amore » uni cation scale su fficiently high to avoid proton decay. In addition, this model provides a good dark matter candidates, whose stability is guaranteed by a Z 2 symmetry present after the spontaneous breaking of the intermediate gauge symmetries. In addition, we discuss prospects for testing these models in the forthcoming LHC experiments and dark matter detection experiments.« less

Surface Plasmon Resonance Based Sensitive Immunosensor for Benzaldehyde Detection

NASA Astrophysics Data System (ADS)

Onodera, Takeshi; Shimizu, Takuzo; Miura, Norio; Matsumoto, Kiyoshi; Toko, Kiyoshi

Fragrant compounds used to add flavor to beverages remain in the manufacturing line after the beverage manufacturing process. Line cleanliness before the next manufacturing cycle is difficult to estimate by sensory analysis, making excessive washing necessary. A new measurement system to determine line cleanliness is desired. In this study, we attempted to detect benzaldehyde (Bz) using an anti-Bz monoclonal antibody (Bz-Ab) and a surface plasmon resonance (SPR) sensor. We fabricated two types of sensor chips using self-assembled monolayers (SAMs) and investigated which sensor surface exhibited higher sensitivity. In addition, anti-Bz antibody conjugated with horseradish peroxidase (HRP-Bz-Ab) was used to enhance the SPR signal. A detection limit of ca. 9ng/mL (ppb) was achieved using an immobilized 4-carboxybenzaldehyde sensor surface using SAMs containing ethylene glycol. When the HRP-Bz-Ab concentration was reduced to 30ng/mL, a detection limit of ca. 4ng/mL (ppb) was achieved for Bz.

Heavy vector partners of the light composite Higgs

DOE PAGES

Lane, Kenneth; Pritchett, Lukas

2015-12-07

If the Higgs boson H(125)is a composite due to new strong interactions at high energy, it has spin-one partners, ρ H and a H, analogous to the ρand a 1 mesons of QCD. These bosons are heavy, their mass determined by the strong interaction scale. The strongly interacting particles light enough for ρ H and a H to decay to are the longitudinal weak bosons V L = W L, Z L and the Higgs boson H. These decay signatures are consistent with resonant diboson excesses recently reported near 2TeVby ATLAS and CMS. We calculate σ × BR(ρ H →more » VV) = few fb and σ × BR(a H → VH) = 0.5–1fb at √s = 8TeV, increasing by a factor of 5–7 at 13TeV. As a result, other tests of the hypothesis of the strong-interaction nature of the diboson resonances are suggested.« less

Measurement of the polarized structure function σL T' for p ( e→ , e' π+ ) n in the Δ ( 1232 ) resonance region

NASA Astrophysics Data System (ADS)

Joo, K.; Smith, L. C.; Aznauryan, I. G.; Burkert, V. D.; Minehart, R.; Adams, G.; Ambrozewicz, P.; Anciant, E.; Anghinolfi, M.; Asavapibhop, B.; Asryan, G.; Audit, G.; Auger, T.; Avakian, H.; Bagdasaryan, H.; Ball, J. P.; Barrow, S.; Batourine, V.; Battaglieri, M.; Beard, K.; Bektasoglu, M.; Benmouna, N.; Bianchi, N.; Biselli, A. S.; Boiarinov, S.; Bonner, B. E.; Bouchigny, S.; Bradford, R.; Branford, D.; Briscoe, W. J.; Brooks, W. K.; Bültmann, S.; Butuceanu, C.; Calarco, J. R.; Carman, D. S.; Carnahan, B.; Cetina, C.; Chen, S.; Ciciani, L.; Cole, P. L.; Cords, D.; Corvisiero, P.; Crabb, D.; Crannell, H.; Cummings, J. P.; de Sanctis, E.; Devita, R.; Degtyarenko, P. V.; Dennis, L.; Deur, A.; Dharmawardane, K. V.; Dhuga, K. S.; Djalali, C.; Dodge, G. E.; Doughty, D.; Dragovitsch, P.; Dugger, M.; Dytman, S.; Dzyubak, O. P.; Egiyan, H.; Egiyan, K. S.; Elouadrhiri, L.; Empl, A.; Eugenio, P.; Fersch, R.; Feuerbach, R. J.; Forest, T. A.; Funsten, H.; Gaff, S. J.; Garçon, M.; Gavalian, G.; Gilad, S.; Gilfoyle, G. P.; Giovanetti, K. L.; Gothe, R. W.; Griffioen, K. A.; Guidal, M.; Guillo, M.; Guler, N.; Guo, L.; Gyurjyan, V.; Hadjidakis, C.; Hakobyan, R. S.; Hardie, J.; Heddle, D.; Hersman, F. W.; Hicks, K.; Hleiqawi, I.; Holtrop, M.; Hu, J.; Hyde-Wright, C. E.; Ilieva, Y.; Ireland, D.; Ito, M. M.; Jenkins, D.; Juengst, H. G.; Kellie, J. D.; Kelley, J. H.; Khandaker, M.; Kim, K. Y.; Kim, K.; Kim, W.; Klein, A.; Klein, F. J.; Klimenko, A. V.; Klusman, M.; Kossov, M.; Koubarovski, V.; Kramer, L. H.; Kuhn, S. E.; Kuhn, J.; Lachniet, J.; Laget, J. M.; Langheinrich, J.; Lawrence, D.; Lee, T.; Livingston, K.; Lukashin, K.; Manak, J. J.; Marchand, C.; McAleer, S.; McNabb, J. W.; Mecking, B. A.; Mestayer, M. D.; Meyer, C. A.; Mikhailov, K.; Mirazita, M.; Miskimen, R.; Mokeev, V.; Morand, L.; Morrow, S. A.; Muccifora, V.; Mueller, J.; Mutchler, G. S.; Napolitano, J.; Nasseripour, R.; Nelson, S. O.; Niccolai, S.; Niculescu, G.; Niculescu, I.; Niczyporuk, B. B.; Niyazov, R. A.; Nozar, M.; O'Rielly, G. V.; Osipenko, M.; Ostrovidov, A. I.; Park, K.; Pasyuk, E.; Peterson, G.; Philips, S. A.; Pivnyuk, N.; Pocanic, D.; Pogorelko, O.; Polli, E.; Pozdniakov, S.; Preedom, B. M.; Price, J. W.; Prok, Y.; Protopopescu, D.; Qin, L. M.; Raue, B. A.; Riccardi, G.; Ricco, G.; Ripani, M.; Ritchie, B. G.; Ronchetti, F.; Rosner, G.; Rossi, P.; Rowntree, D.; Rubin, P. D.; Sabatié, F.; Sabourov, K.; Salgado, C.; Santoro, J. P.; Sapunenko, V.; Schumacher, R. A.; Serov, V. S.; Sharabian, Y. G.; Shaw, J.; Simionatto, S.; Skabelin, A. V.; Smith, E. S.; Sober, D. I.; Spraker, M.; Stavinsky, A.; Stepanyan, S.; Stepanyan, S. S.; Stokes, B. E.; Stoler, P.; Strakovsky, I. I.; Strauch, S.; Taiuti, M.; Taylor, S.; Tedeschi, D. J.; Thoma, U.; Thompson, R.; Tkabladze, A.; Todor, L.; Tur, C.; Ungaro, M.; Vineyard, M. F.; Vlassov, A. V.; Wang, K.; Weinstein, L. B.; Weller, H.; Weygand, D. P.; Williams, M.; Wolin, E.; Wood, M. H.; Yegneswaran, A.; Yun, J.; Zana, L.

2004-10-01

The polarized longitudinal-transverse structure function σL T' has been measured using the p ( e→ , e' π+ ) n reaction in the Δ ( 1232 ) resonance region at Q2 =0.40 and 0.65 GeV2 . No previous σL T' data exist for this reaction channel. The kinematically complete experiment was performed at the Jefferson Lab with the CEBAF large acceptance spectrometer using longitudinally polarized electrons at an energy of 1.515 GeV . A partial-wave analysis of the data shows generally better agreement with recent phenomenological models of pion electroproduction compared to the previously measured π0 p channel. A fit to both π0 p and π+ n channels using a unitary isobar model suggests the unitarized Born terms provide a consistent description of the nonresonant background. The t -channel pion pole term is important in the π0 p channel through a rescattering correction, which could be model dependent.

Nuclear magnetic resonance studies of amino acids and proteins. Side-chain mobility of methionine in the crystalline amonio acid and in crystallne sperm whale (Physeter catodon) myoglobin

DOE Office of Scientific and Technical Information (OSTI.GOV)

Keniry, M.A.; Rothgeb, T.M.; Smith, R.L.

1983-04-12

Deuterium (/sup 2/H) nuclear magnetic resonance (NMR) spectra and spin-lattice relaxation times (T/sub 1/) were obtained of L-(epsilon-/sup 2/H/sub 3/)methionine, L-(epsilon-/sup 2/H/sub 3/)methionine in a D,L lattice, and (S-methyl-/sup 2/H/sub 3/)methionine in the crystalline solid state, as a function of temperature, in addition to obtaining /sup 2/H T/sub 1/ and line-width results as a function of temperature on (epsilon-/sup 2/H/sub 3/)methionine-labeled sperm whale (Physeter catodon) myoglobins by using the method of magnetic ordering. Also recorded were /sup 13/C cross-polarization ''magic-angle'' sample-spinning NMR spectra of (epsilon-/sup 13/C)methionine-labeled crystalline cyanoferrimyoglobin (at 37.7 MHz, corresponding to a magnetic field strength of 3.52 T)more » and of the same protein in aqueous solution. (JMT)« less

Design, synthesis, and antiviral activity of novel rutin derivatives containing 1, 4-pentadien-3-one moiety.

PubMed

Han, Yu; Ding, Yan; Xie, Dandan; Hu, Deyu; Li, Pei; Li, Xiangyang; Xue, Wei; Jin, Linhong; Song, Baoan

2015-03-06

Rutin (compound 5) and some compounds (compounds 1-4 and 6) were isolated from Artemisia princeps Pamp (A. princeps Pamp.) and a series of novel rutin derivatives containing 1,4-pentadien-3-one moiety were designed and synthesized. The target compounds were characterized by proton nuclear magnetic resonance spectroscopy ((1)H NMR), carbon nuclear magnetic resonance spectroscopy ((13)C NMR), and ESI-MS. Bioassay results indicated that some of the compounds showed good to excellent antiviral activities against tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV) at 500 μg/mL in vivo. The 50% effective concentrations (EC50) of the compound 7r against CMV was 394.78 μg/mL, which was better than that of Ningnanmycin (432.22 μg/mL). These results indicated that novel rutin derivatives containing 1,4-pentadien-3-one moiety can effectively control CMV. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

Minimal supersymmetric B - L extension of the standard model, heavy H and light h Higgs boson production and decay at future e + e - linear colliders

NASA Astrophysics Data System (ADS)

Ramírez-Sánchez, F.; Gutierrez-Rodríguez, A.; Hernández-Ruiz, M. A.

2017-10-01

We study the phenomenology of the light h and heavy H Higgs boson production and decay in the context of a U(1) B - L extension of the standard model with an additional Z´ boson at future e + e - linear colliders with center-of-mass energies of √𝑠 = 500 - 3000 GeV and integrated luminosities of L = 500 - 2000 fb-1. The study includes the processes e + e - → (Z, Z´) → Zh and e + e - → (Z, Z´) → ZH, considering both the resonant and non-resonant effects. We find that the total number of expected Zh and ZH events can reach 106 and 105, respectively, which is a very optimistic scenario allowing us to perform precision measurements for both Higgs bosons h and H, as well as for the Z‧ boson in future high-energy and high-luminosity e + e - colliders.

Gastric Fluid Volume Change After Oral Rehydration Solution Intake in Morbidly Obese and Normal Controls: A Magnetic Resonance Imaging-Based Analysis.

PubMed

Shiraishi, Toshie; Kurosaki, Dai; Nakamura, Mitsuyo; Yazaki, Taiji; Kobinata, Satomi; Seki, Yosuke; Kasama, Kazunori; Taniguchi, Hideki

2017-04-01

Although preoperative fluid intake 2 hours before anesthesia is generally considered safe, there are concerns about delayed gastric emptying in obese subjects. In this study, the gastric fluid volume (GFV) change in morbidly obese subjects was investigated after ingesting an oral rehydration solution (ORS) and then compared with that in nonobese subjects. GFV change over time after the ingestion of 500 mL of ORS containing 2.5% carbohydrate (OS-1) was measured in 10 morbidly obese subjects (body mass index [BMI], >35) scheduled for bariatric surgery and 10 nonobese (BMI, 19-24) using magnetic resonance imaging. After 9 hours of fasting, magnetic resonance imaging scans were performed at preingestion, 0 min (just after ingestion), and every 30 minutes up to 120 minutes. GFV values were compared between morbidly obese and control groups and also between preingestion and postingestion time points. The morbidly obese group had a significantly higher body weight and BMI than the control group (mean body weight and BMI in morbidly obese, 129.6 kg and 46.3 kg/m, respectively; control, 59.5 kg and 21.6 kg/m, respectively). GFV was significantly higher in the morbidly obese subjects compared with the control group at preingestion (73 ± 30.8 mL vs 31 ± 19.9 mL, P = .001) and at 0 minutes after ingestion (561 ± 30.8 mL vs 486 ± 42.8 mL; P < .001). GFV declined rapidly in both groups and reached fasting baseline levels by 120 minutes (morbidly obese, 50 ± 29.5 mL; control, 30 ± 11.6 mL). A significant correlation was observed between preingestion residual GFV and body weight (r = .66; P = .001). Morbidly obese subjects have a higher residual gastric volume after 9 hours of fasting compared with subjects with a normal BMI. However, no differences were observed in gastric emptying after ORS ingestion in the 2 populations, and GFVs reached baseline within 2 hours after ORS ingestion. Further studies are required to confirm whether the preoperative fasting and fluid management that are recommended for nonobese patients could also be applied to morbidly obese patients.

Metal-ligand Covalency of Iron Complexes from High-Resolution Resonant Inelastic X-ray Scattering

PubMed Central

Lundberg, Marcus; Kroll, Thomas; DeBeer, Serena; Bergmann, Uwe; Wilson, Samuel A.; Glatzel, Pieter; Nordlund, Dennis; Hedman, Britt; Hodgson, Keith O.; Solomon, Edward I.

2013-01-01

Data from Kα resonant inelastic X-ray scattering (RIXS) have been used to extract electronic structure information, i.e., the covalency of metal-ligand bonds, for four iron complexes using an experimentally based theoretical model. Kα RIXS involves resonant 1s → 3d excitation and detection of the 2p → 1s (Kα) emission. This two-photon process reaches similar final states as single-photon L-edge (2p → 3d) X-ray absorption spectroscopy (XAS), but involves only hard X-rays and can therefore be used to get high-resolution L-edge-like spectra for metal proteins, solution catalysts and their intermediates. To analyze the information content of Kα RIXS spectra, data have been collected for four characteristic σ-donor and π-backdonation complexes; ferrous tacn [FeII(tacn)2]Br2, ferrocyanide [FeII(CN)6]K4, ferric tacn [FeIII(tacn)2]Br3 and ferricyanide [FeIII(CN)6]K3. From these spectra metal-ligand covalencies can be extracted using a charge-transfer multiplet model, without previous information from the L-edge XAS experiment. A direct comparison of L-edge XAS and Kα RIXS spectra show that the latter reaches additional final states, e.g., when exciting into the eg (σ*) orbitals, and the splitting between final states of different symmetry provides an extra dimension that makes Kα RIXS a more sensitive probe of σ-bonding. Another key difference between L-edge XAS and Kα RIXS is the π-backbonding features in ferro- and ferricyanide that are significantly more intense in L-edge XAS compared to Kα RIXS. This shows that two methods are complimentary in assigning electronic structure. The Kα RIXS approach can thus be used as a stand-alone method, in combination with L-edge XAS for strongly covalent systems that are difficult to probe by UV/Vis spectroscopy, or as an extension to conventional absorption spectroscopy for a wide range of transition metal enzymes and catalysts. PMID:24131028

Determination of thorium (IV) using isophthalaldehyde-tetrapyrrole as probe by resonance light scattering, second-order scattering and frequency-doubling scattering spectra

NASA Astrophysics Data System (ADS)

Wang, Jiao; Xue, Jinhua; Xiao, Xilin; Xu, Li; Jiang, Min; Peng, Pengcheng; Liao, Lifu

2017-12-01

The coordination reaction of thorium (IV) with a ditopic bidentate ligand to form supramolecular polymer was studied by resonance light scattering (RLS) spectra, second-order scattering (SOS) spectra and frequency-doubling scattering (FDS) spectra, respectively. The ditopic bidentate ligand is isophthalaldehyde-tetrapyrrole (IPTP). It was synthesized through a condensation reaction of isophthalaldehyde with pyrrole. The formation of supramolecular polymer results in remarkable intensity enhancements of the three light scattering signals. The maximum scattering wavelengths of RLS, FDS and SOS were 290, 568 and 340 nm, respectively. The reaction was used to establish new light scattering methods for the determination of thorium (IV) by using IPTP as probe. Under optimum conditions, the intensity enhancements of RLS, SOS and FDS were directly proportional to the concentration of thorium (IV) in the ranges of 0.01 to 1.2 μg mL- 1, 0.05 to 1.2 μg mL- 1 and 0.05 to 1.2 μg mL- 1, respectively. The detection limits were 0.003 μg mL- 1, 0.012 μg mL- 1 and 0.021 μg mL- 1, respectively. The methods were suitable for analyzing thorium (IV) in actual samples. The results show acceptable recoveries and precision compared with a reference method.

Enhanced spectrophotometric detection of Hg in water samples by surface plasmon resonance of Au nanoparticles after preconcentration with vortex-assisted liquid-liquid microextraction

NASA Astrophysics Data System (ADS)

Martinis, Estefanía M.; Wuilloud, Rodolfo G.

2016-10-01

This article presents an efficient, simple, and cost-effective method for the determination of trace amounts of Hg by vortex-assisted liquid-liquid microextraction (VALLME) coupled to microvolume UV-Vis spectrophotometry. This method correlates changes in the intensity of localized surface plasmon resonance (LSPR) of tetraoctylammonium bromide (TOABr) coated Au nanoparticles (NPs) after interaction with Hg2+ ion. Spectroscopic measurements of the TOABr-coated Au NPs phase with particular absorption properties (strong and well-defined absorption bands) after analyte extraction by VALLME, provide an accurate and sensitive determination of Hg in water samples, comparable with measurements obtained by atomic absorption spectrometry (AAS). Different variables including sample volume, extraction time, and TOABr-coated Au NPs dispersion volume were carefully studied; final experimental conditions were 5 mL, 120 μL and 5 min respectively. The limit of detection (LOD) was 0.8 ng mL- 1. The calibration curve was linear at concentrations between the limit of quantification (LOQ) (4.9 ng mL- 1) and up to at least 120 ng mL- 1 of Hg. The relative standard deviation for six replicate determinations of 20 ng mL- 1 of Hg was 4.7%. This method exhibited an excellent analytical performance in terms of selectivity and sensitivity and it was finally applied for Hg determination in spiked tap and mineral water samples.

Resonant excitation of high order modes in the 3.9 GHz cavity of the Linac Coherent Light Source

DOE PAGES

Lunin, A.; Khabiboulline, T.; Solyak, N.; ...

2018-02-06

Construction of the Linac Coherent Light Source II (LCLS-II) is underway for the world’s first hard x-ray free-electron laser. A central part of the LCLS-II project is a 4 GeV superconducting radio frequency electron linac that will operate in the continuous wave (cw) mode. The linac is segmented into four sections named as L0, L1, L2, and L3. Two 3.9 GHz cryomodules, each housing of eight third-harmonic cavities similar to the cavities developed for the European X-ray Free Electron Laser (XFEL), will be used in section L1 of the linac for linearizing the longitudinal beam profile. Here in this paper, we presentmore » a study of trapped high order modes (HOMs) excited by a cw electron beam in the third-harmonic cavities of the LCLS-II linac. A detailed comparison of the original XFEL design and the LCLS-II design with a modified end group is performed in order to estimate the effect of a reduced beam pipe aperture on the efficiency of HOM damping. Furthermore, we apply a statistical analysis of the eigenmode spectrum for the estimation of the probability of resonant HOM losses and influence of HOMs on beam dynamics.« less

The costs and effects of contrast-enhanced magnetic resonance angiography and digital substraction angiography on quality of life in patients with peripheral arterial disease.

PubMed

Bosma, Jan; Dijksman, Lea M; Lam, Kayan; Wisselink, Willem; van Swijndregt, Alexander D Montauban; Vahl, Anco

2014-04-01

Contrast-enhanced magnetic resonance angiography (MRA) and intra-arterial digital subtraction angiography (DSA) both have a high diagnostic performance in the imaging of peripheral arterial occlusive disease (PAOD). However, little is known about the effects of initial, preoperative imaging using MRA or DSA on quality of life (QoL) in relation to costs (cost-utility). To compare cost-utility of treatment strategies using either MRA or DSA as the principal imaging tool, related to QoL, in patients with PAOD. In a prospective subgroup analysis of patients randomized between MRA and DSA (n = 79) for preoperative imaging, QoL questionnaires (SF-36) were obtained at randomization and at 4-month follow-up. Cost-effectiveness from hospital perspective was subsequently compared between groups and the difference in gained or lost QoL per € spent assessed using bootstrap analysis. No difference in quality of life was found. A treatment trajectory employing MRA as the principal imaging modality was almost 20% cheaper, leading to a better cost-utility ratio in favor of MRA. A treatment plan for peripheral arterial occlusive disease employing MRA versus DSA as the principal imaging modality yields a better cost/QoL ratio for MRA.

Resonant excitation of high order modes in the 3.9 GHz cavity of the Linac Coherent Light Source

NASA Astrophysics Data System (ADS)

Lunin, A.; Khabiboulline, T.; Solyak, N.; Sukhanov, A.; Yakovlev, V.

2018-02-01

Construction of the Linac Coherent Light Source II (LCLS-II) is underway for the world's first hard x-ray free-electron laser. A central part of the LCLS-II project is a 4 GeV superconducting radio frequency electron linac that will operate in the continuous wave (cw) mode. The linac is segmented into four sections named as L 0 , L 1 , L 2 , and L 3 . Two 3.9 GHz cryomodules, each housing of eight third-harmonic cavities similar to the cavities developed for the European X-ray Free Electron Laser (XFEL), will be used in section L 1 of the linac for linearizing the longitudinal beam profile. In this paper, we present a study of trapped high order modes (HOMs) excited by a cw electron beam in the third-harmonic cavities of the LCLS-II linac. A detailed comparison of the original XFEL design and the LCLS-II design with a modified end group is performed in order to estimate the effect of a reduced beam pipe aperture on the efficiency of HOM damping. Furthermore, we apply a statistical analysis of the eigenmode spectrum for the estimation of the probability of resonant HOM losses and influence of HOMs on beam dynamics.

Reduced magnetohydrodynamic theory of oblique plasmoid instabilities

NASA Astrophysics Data System (ADS)

Baalrud, S. D.; Bhattacharjee, A.; Huang, Y.-M.

2012-02-01

The three-dimensional nature of plasmoid instabilities is studied using the reduced magnetohydrodynamic equations. For a Harris equilibrium with guide field, represented by Bo=Bpotanh(x /λ)ŷ+Bzoẑ, a spectrum of modes are unstable at multiple resonant surfaces in the current sheet, rather than just the null surface of the poloidal field Byo(x)=Bpotanh(x /λ), which is the only resonant surface in 2D or in the absence of a guide field. Here, Bpo is the asymptotic value of the equilibrium poloidal field, Bzo is the constant equilibrium guide field, and λ is the current sheet width. Plasmoids on each resonant surface have a unique angle of obliquity θ ≡arctan(kz/ky). The resonant surface location for angle θ is xs=λarctanh(μ), where μ =tanθBzo/Bpo and the existence of a resonant surface requires |θ |

206Pb+n resonances for E=600-900 keV: Neutron strength functions

NASA Astrophysics Data System (ADS)

Horen, D. J.; Harvey, J. A.; Hill, N. W.

1981-11-01

Data from high resolution neutron transmission and differential scattering measurements performed on 206Pb have been analyzed for E=600-900 keV. Resonance parameters (i.e., E, l, J, and Γn) have been deduced for many of the 161 resonances observed. Strength functions and potential phase shifts for s-, p-, and d-wave neutrons for En-0-900 keV are compared with optical model calculations. It is found that the phase contributed by the external R function as well as the integrated neutron strength functions can be reproduced for the s and d waves with a well depth of V0=50.4 MeV for the real potential and WD=6.0 MeV for an imaginary surface potential. Somewhat smaller values (V0=48.7 MeV and WD=2.0 MeV) are required to reproduce the p-wave data. These values of the real potential are also found to give the experimentally observed binding energies for the 4s12, 3d32, and 3d52 single particle levels (V0=50.4 MeV), and the 3p12 single particle level (V0=48.7 MeV). Nuclear level densities for s and d waves are found to be well represented by a constant temperature model. However, the model under estimates the number of p-wave resonances. NUCLEAR REACTIONS 206Pb(n), (n,n), E=600-900 keV; measured σT(E), σ(E,θ). 207Pb deduced resonance parameters, Jπ, Γn, neutron strength functions, optical model parameters for l=0,1,2.

Distinguishing black-hole spin-orbit resonances by their gravitational-wave signatures

NASA Astrophysics Data System (ADS)

Gerosa, Davide; O'Shaughnessy, Richard; Kesden, Michael; Berti, Emanuele; Sperhake, Ulrich

2014-06-01

If binary black holes form following the successive core collapses of sufficiently massive binary stars, precessional dynamics may align their spins, Smathvariant="bold">1 and Smathvariant="bold">2, and the orbital angular momentum L into a plane in which they jointly precess about the total angular momentum J. These spin orientations are known as spin-orbit resonances since S1, S2, and L all precess at the same frequency to maintain their planar configuration. Two families of such spin-orbit resonances exist, differentiated by whether the components of the two spins in the orbital plane are either aligned or antialigned. The fraction of binary black holes in each family is determined by the stellar evolution of their progenitors, so if gravitational-wave detectors could measure this fraction they could provide important insights into astrophysical formation scenarios for binary black holes. In this paper, we show that even under the conservative assumption that binary black holes are observed along the direction of J (where precession-induced modulations to the gravitational waveforms are minimized), the waveforms of many members of each resonant family can be distinguished from all members of the other family in events with signal-to-noise ratios ρ ≃10, typical of those expected for the first detections with Advanced LIGO and Virgo. We hope that our preliminary findings inspire a greater appreciation of the capability of gravitational-wave detectors to constrain stellar astrophysics and stimulate further studies of the distinguishability of spin-orbit resonant families in more expanded regions of binary black-hole parameter space.

Search for new particles decaying to diject in 7 TeV proton-proton collisions at CMS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ozturk, Sertac

2011-03-01

This thesis presents a measurement of the dijet invariant mass spectrum and search for new particles decaying to dijets at CMS in 7 TeV pp collisions using data corresponding to an integrated luminosity of 2.875 pb -1. The measured dijet mass distribution is compared to QCD prediction from PYTHIA . It is required the pseudorapidity separation of the two jets to satisfy |Dh| < 1.3 with each jet inside the region of |{eta}| < 2.5. The observed dijet mass spectrum is fitted by a smooth function to search for dijet resonances. Since there is no evidence for dijet resonances, themore » upper limits at 95% Confidence Level (C.L.) on the resonance cross section are set. These generic cross section limits are compared with theoretical predictions for the cross section for several models of new particles: string resonances, axigluons, colorons, excited quarks, E 6 diquarks, Randall-Sundrum gravitons, W' and Z'. It is excluded at 95% C.L. string resonances in the mass range 0.50 < M(S) < 2.50 TeV, excited quarks in the mass range 0.50 < M(q*) < 1.58 TeV, axigluons and colorons in the mass ranges 0.50 < M(A) < 1.17 TeV and 1.47 < M(A) < 1.52 TeV, and E 6 diquarks in the mass ranges 0.50 < M(D) < 0.58 TeV, 0.97 < M(D) < 1.08 TeV, and 1.45 < M(D) < 1.60 TeV. These exclusions extend previously published limits on all models.« less

Multi-tunable microelectromechanical system (MEMS) resonators

DOEpatents

Stalford, Harold L [Norman, OK; Butler, Michael A [Andover, MA; Schubert, W Kent [Albuquerque, NM

2006-08-22

A method for tuning a vibratory device including a cantilevered resonator comprising the steps of increasing a voltage V.sub.0 supplied to the vibratory device to thereby increase the bandwidth of the vibratory device; and keeping the resonant frequency of the vibratory device at substantially that natural frequency of the cantilevered resonator, wherein the vibratory device comprises: a capacitor including a movable plate and a fixed plate spaced from each other, the movable plate being part of the cantilevered resonator; a voltage source connected to the capacitor for providing voltage V.sub.0 across the capacitor to produce an attractive force between movable plate and fixed plate; a circuit connecting the voltage source to the capacitor; and a load resistor in said circuit having a resistance R.sub.L satisfying the following equation: .mu..omega..times..times..lamda. ##EQU00001## where: .mu. is at least 10; .omega..sub.0 is the beam constant for the cantilevered resonator; c.sub.0 is the capacitance for the capacitor; and .lamda. is the voltage dependent coupling parameter for voltage V.sub.0.

Whispering Gallery Mode Resonators for Rapid Label-Free Biosensing in Small Volume Droplets

PubMed Central

Wildgen, Sarah M.; Dunn, Robert C.

2015-01-01

Rapid biosensing requires fast mass transport of the analyte to the surface of the sensing element. To optimize analysis times, both mass transport in solution and the geometry and size of the sensing element need to be considered. Small dielectric spheres, tens of microns in diameter, can act as label-free biosensors using whispering gallery mode (WGM) resonances. WGM resonances are sensitive to the effective refractive index, which changes upon analyte binding to recognition sites on functionalized resonators. The spherical geometry and tens of microns diameter of these resonators provides an efficient target for sensing while their compact size enables detection in limited volumes. Here, we explore conditions leading to rapid analyte detection using WGM resonators as label-free sensors in 10 μL sample droplets. Droplet evaporation leads to potentially useful convective mixing, but also limits the time over which analysis can be completed. We show that active droplet mixing combined with initial binding rate measurements is required for accurate nanomolar protein quantification within the first minute following injection. PMID:25806835

Neutron Spin Resonance in the 112-Type Iron-Based Superconductor.

PubMed

Xie, Tao; Gong, Dongliang; Ghosh, Haranath; Ghosh, Abyay; Soda, Minoru; Masuda, Takatsugu; Itoh, Shinichi; Bourdarot, Frédéric; Regnault, Louis-Pierre; Danilkin, Sergey; Li, Shiliang; Luo, Huiqian

2018-03-30

We use inelastic neutron scattering to study the low-energy spin excitations of the 112-type iron pnictide Ca_{0.82}La_{0.18}Fe_{0.96}Ni_{0.04}As_{2} with bulk superconductivity below T_{c}=22  K. A two-dimensional spin resonance mode is found around E=11  meV, where the resonance energy is almost temperature independent and linearly scales with T_{c} along with other iron-based superconductors. Polarized neutron analysis reveals the resonance is nearly isotropic in spin space without any L modulations. Because of the unique monoclinic structure with additional zigzag arsenic chains, the As 4p orbitals contribute to a three-dimensional hole pocket around the Γ point and an extra electron pocket at the X point. Our results suggest that the energy and momentum distribution of the spin resonance does not directly respond to the k_{z} dependence of the fermiology, and the spin resonance intrinsically is a spin-1 mode from singlet-triplet excitations of the Cooper pairs in the case of weak spin-orbital coupling.

A sensitive and selective resonance Rayleigh scattering method for quick detection of avidin using affinity labeling Au nanoparticles

NASA Astrophysics Data System (ADS)

Wang, Qi; Huang, Xi; Fu, Xuan; Deng, Huan; Ma, Meihu; Cai, Zhaoxia

2016-06-01

Avidin is a glycoprotein with antinutritional property, which should be limited in daily food. We developed an affinity biosensor system based on resonance Rayleigh scattering (RRS) and using affinity biotin labeling Au nanoparticles (AuNPs). This method was selective and sensitive for quick avidin detection due to the avidin-biotin affinitive interaction. Under optimal conditions, RRS intensity of biotin-AuNPs increase linearly with an increasing concentration of avidin from 5 to 160 ng/mL. The lower limit of detection was 0.59 ng/mL. This rapid and selective avidin detection method was used in synthetic samples and egg products with recoveries of between 102.97 and 107.92%, thereby demonstrating the feasible and practical application of this assay.

Free radical scavenging activities of yellow gentian (Gentiana lutea L.) measured by electron spin resonance.

PubMed

Kusar, A; Zupancic, A; Sentjurc, M; Baricevic, D

2006-10-01

Yellow gentian (Gentiana lutea L.) is a herbal species with a long-term use in traditional medicine due to its digestive and stomachic properties. This paper presents an investigation of the free radical scavenging activity of methanolic extracts of yellow gentian leaves and roots in two different systems using electron spin resonance (ESR) spectrometry. Assays were based on the stable free radical 1,1-diphenyl-2-picrylhydrazyl (DPPH) and the superoxide radicals (O2*-) generated by the xanthine/xanthine oxidase (X/XO) system. The results of gentian methanolic extracts were compared with the antioxidant capacity of synthetic antioxidant butylated hydroxyanisole (BHA). This study proves that yellow gentian leaves and roots exhibit considerable antioxidant properties, expressed either by their capability to scavenge DPPH or superoxide radicals.

Quantifying covalent interactions with resonant inelastic soft X-ray scattering: Case study of Ni 2+ aqua complex

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kunnus, K.; Josefsson, I.; Schreck, S.

We analyze the effects of covalent interactions in Ni 2p3d resonant inelastic X-ray scattering (RIXS) spectra from aqueous Ni 2+ ions and find that the relative RIXS intensities of ligand-to-metal charge-transfer final states with respect to the ligand-field final states reflect the covalent mixing between Ni 3d and water orbitals. Specifically, the experimental intensity ratio at the Ni L 3-edge allows to determine that the Ni 3d orbitals have on average 5.5% of water character. Here, we propose that 2p3d RIXS at the Ni L 3-edge can be utilized to quantify covalency in Ni complexes without the use of externalmore » references or simulations.« less

N* resonances from KΛ amplitudes in sliced bins in energy

NASA Astrophysics Data System (ADS)

Anisovich, A. V.; Burkert, V.; Hadžimehmedović, M.; Ireland, D. G.; Klempt, E.; Nikonov, V. A.; Omerović, R.; Sarantsev, A. V.; Stahov, J.; Švarc, A.; Thoma, U.

2017-12-01

The two reactions γ p→ K+Λ and π- p→ K0Λ are analyzed to determine the leading photoproduction multipoles and the pion-induced partial wave amplitudes in slices of the invariant mass. The multipoles and the partial-wave amplitudes are simultaneously fitted in a multichannel Laurent+Pietarinen model (L+P model), which determines the poles in the complex energy plane on the second Riemann sheet close to the physical axes. The results from the L+P fit are compared with the results of an energy-dependent fit based on the Bonn-Gatchina (BnGa) approach. The study confirms the existence of several poles due to nucleon resonances in the region at about 1.9 GeV with quantum numbers JP = 1/2+, 3/2+, 1/2-, 3/2-, 5/2-.

The 12 micron band of ethane - High-resolution laboratory analysis with candidate lines for infrared heterodyne searches

NASA Technical Reports Server (NTRS)

Atakan, A. K.; Blass, W. E.; Halsey, G. W.; Reuter, D. C.; Susskind, J.; Brault, J. W.; Daunt, S. J.; Jennings, D. E.

1984-01-01

Attention is given to the results of a laboratory study of the v9 band of ethane at 12 microns, using both high resolution Fourier transform and diode laser absorption spectroscopy. The analysis to which about 2000 transitions in this band have been subjected includes the normal rotational terms as well as the higher order effects of l-doubling, l-resonance, internal rotation, and a Coriolis resonance with the 3v4 state. A model is presented for the v9 band which is able to reproduce the observed features to an accuracy of better than 0.001/cm, and a list has been compiled for v9 transitions, occurring near C-14O2 laser lines, that are good candidates for laser heterodyne searches.

Staphylococcus aureus Peptidoglycan Stem Packing by Rotational-Echo Double Resonance NMR Spectroscopy

PubMed Central

Kim, Sung Joon; Singh, Manmilan; Preobrazhenskaya, Maria; Schaefer, Jacob

2013-01-01

Staphylococcus aureus grown in the presence of an alanine-racemase inhibitor was labeled with D-[1-13C]alanine and L-[15N]alanine to characterize some details of the peptidoglycan tertiary structure. Rotational-echo double-resonance NMR of intact whole cells was used to measure internuclear distances between 13C and 15N of labeled amino acids incorporated in the peptidoglycan, and from those labels to 19F of a glycopeptide drug specifically bound to the peptidoglycan. The observed 13C-15N average distance of 4.1 to 4.4 Å between D- and L-alanines in nearest-neighbor peptide stems is consistent with a local, tightly packed, parallel-stem architecture for a repeating structural motif within the peptidoglycan of S. aureus. PMID:23617832

Correlation lengths of the wigner-crystal order in a two-dimensional electron system at high magnetic fields.

PubMed

Ye, P D; Engel, L W; Tsui, D C; Lewis, R M; Pfeiffer, L N; West, K

2002-10-21

The insulator terminating the fractional quantum Hall series at low Landau level filling nu is generally taken to be a pinned Wigner crystal (WC), and exhibits a microwave resonance that is interpreted as a WC pinning mode. For a high quality sample at several densities, n, we find maxima in resonance peak frequency, f(pk), vs magnetic field, B. L, the correlation length of WC order, is calculated from f(pk). For each n, L vs nu tends at low nu toward a line with positive intercept; the fit is accurate over as much as a factor of 5 range of nu. The linear behavior is interpreted as due to B compressing the electron wave functions, to alter the effective electron-impurity interaction.

Probing single magnon excitations in Sr₂IrO₄ using O K-edge resonant inelastic x-ray scattering.

PubMed

Liu, X; Dean, M P M; Liu, J; Chiuzbăian, S G; Jaouen, N; Nicolaou, A; Yin, W G; Rayan Serrao, C; Ramesh, R; Ding, H; Hill, J P

2015-05-27

Resonant inelastic x-ray scattering (RIXS) at the L-edge of transition metal elements is now commonly used to probe single magnon excitations. Here we show that single magnon excitations can also be measured with RIXS at the K-edge of the surrounding ligand atoms when the center heavy metal elements have strong spin-orbit coupling. This is demonstrated with oxygen K-edge RIXS experiments on the perovskite Sr2IrO4, where low energy peaks from single magnon excitations were observed. This new application of RIXS has excellent potential to be applied to a wide range of magnetic systems based on heavy elements, for which the L-edge RIXS energy resolution in the hard x-ray region is usually poor.

Quantifying covalent interactions with resonant inelastic soft X-ray scattering: Case study of Ni 2+ aqua complex

DOE PAGES

Kunnus, K.; Josefsson, I.; Schreck, S.; ...

2016-12-23

We analyze the effects of covalent interactions in Ni 2p3d resonant inelastic X-ray scattering (RIXS) spectra from aqueous Ni 2+ ions and find that the relative RIXS intensities of ligand-to-metal charge-transfer final states with respect to the ligand-field final states reflect the covalent mixing between Ni 3d and water orbitals. Specifically, the experimental intensity ratio at the Ni L 3-edge allows to determine that the Ni 3d orbitals have on average 5.5% of water character. Here, we propose that 2p3d RIXS at the Ni L 3-edge can be utilized to quantify covalency in Ni complexes without the use of externalmore » references or simulations.« less

Iron oxide nanoparticles stabilized with dendritic polyglycerols as selective MRI contrast agents

NASA Astrophysics Data System (ADS)

Nordmeyer, Daniel; Stumpf, Patrick; Gröger, Dominic; Hofmann, Andreas; Enders, Sven; Riese, Sebastian B.; Dernedde, Jens; Taupitz, Matthias; Rauch, Ursula; Haag, Rainer; Rühl, Eckart; Graf, Christina

2014-07-01

Monodisperse small iron oxide nanoparticles functionalized with dendritic polyglycerol (dPG) or dendritic polyglycerol sulfate (dPGS) are prepared. They are highly stable in aqueous solutions as well as physiological media. In particular, oleic acid capped iron oxide particles (core diameter = 11 +/- 1 nm) were modified by a ligand exchange process in a one pot synthesis with dPG and dPGS bearing phosphonate as anchor groups. Dynamic light scattering measurements performed in water and different biological media demonstrate that the hydrodynamic diameter of the particles is only slightly increased by the ligand exchange process resulting in a final diameter of less than 30 nm and that the particles are stable in these media. It is also revealed by magnetic resonance studies that their magnetic relaxivity is reduced by the surface modification but it is still sufficient for high contrast magnetic resonance imaging (MRI). Additionally, incubation of dPGS functionalized iron oxide nanoparticles with human umbilical vein endothelial cells showed a 50% survival at 85 nM (concentration of nanoparticles). Surface plasmon resonance (SPR) studies demonstrate that the dPGS functionalized iron oxide nanoparticles inhibit L-selectin ligand binding whereas the particles containing only dPG do not show this effect. Experiments in a flow chamber with human myelogenous leukemia cells confirmed L-selectin inhibition of the dPGS functionalized iron oxide nanoparticles and with that the L-selectin mediated leukocyte adhesion. These results indicate that dPGS functionalized iron oxide nanoparticles are a promising contrast agent for inflamed tissue probed by MRI.Monodisperse small iron oxide nanoparticles functionalized with dendritic polyglycerol (dPG) or dendritic polyglycerol sulfate (dPGS) are prepared. They are highly stable in aqueous solutions as well as physiological media. In particular, oleic acid capped iron oxide particles (core diameter = 11 +/- 1 nm) were modified by a ligand exchange process in a one pot synthesis with dPG and dPGS bearing phosphonate as anchor groups. Dynamic light scattering measurements performed in water and different biological media demonstrate that the hydrodynamic diameter of the particles is only slightly increased by the ligand exchange process resulting in a final diameter of less than 30 nm and that the particles are stable in these media. It is also revealed by magnetic resonance studies that their magnetic relaxivity is reduced by the surface modification but it is still sufficient for high contrast magnetic resonance imaging (MRI). Additionally, incubation of dPGS functionalized iron oxide nanoparticles with human umbilical vein endothelial cells showed a 50% survival at 85 nM (concentration of nanoparticles). Surface plasmon resonance (SPR) studies demonstrate that the dPGS functionalized iron oxide nanoparticles inhibit L-selectin ligand binding whereas the particles containing only dPG do not show this effect. Experiments in a flow chamber with human myelogenous leukemia cells confirmed L-selectin inhibition of the dPGS functionalized iron oxide nanoparticles and with that the L-selectin mediated leukocyte adhesion. These results indicate that dPGS functionalized iron oxide nanoparticles are a promising contrast agent for inflamed tissue probed by MRI. Electronic supplementary information (ESI) available: A detailed description of the synthesis of the ligands as well as the preparation and functionalization of the iron oxide nanoparticles including their physico-chemical characterization are presented. Further, details of the cell experiments and the SPR experiments are given. Two representative movies are provided showing leukocyte rolling on the ligand coated surface of the flow chamber. See DOI: 10.1039/c3nr04793h

Nonlinear damping of oblique whistler mode waves through Landau resonance

NASA Astrophysics Data System (ADS)

Hsieh, Y.; Omura, Y.

2017-12-01

Nonlinear trapping of electrons through Landau resonance is a characteristic dynamics in oblique whistler-mode wave particle interactions. The resonance velocity of the Landau resonance at quasi-parallel propagation becomes very close to the parallel group velocity of whistler-mode wave at frequency around 0.5 Ωe, causing a long distance of resonant interaction and strong acceleration of resonant electrons [1]. We demonstrate these effective accelerations for electrons with high equatorial pitch angle ( > 60°) by test particle simulations with parameters for the Earth's inner magnetosphere at L=5. In the simulations, we focus on slightly oblique whistler mode waves with wave normal angle < 20°. Analyzing the wave electric field E and the resonant current J, which is composed of electrons undergoing the Landau resonance, we find that the J·E is mainly positive, which denotes the damping of the wave. Furthermore, we confirm that this positive J•E is dominated by transverse component Jperp·Eperp rather than by longitudinal component Jpara·Eperp. The simulation results reveal that the Landau resonance contributes to the nonlinear damping at 0.5 Ωe for whistler mode waves. Reference [1] Hsieh, Y.-K., and Y. Omura (2017), Nonlinear dynamics of electrons interacting with oblique whistler mode chorus in the magnetosphere, J. Geophys. Res. Space Physics, 122, doi:10.1002/2016JA023255.

Anti-resonance scattering at defect levels in the quantum conductance of a one-dimensional system

NASA Astrophysics Data System (ADS)

Sun, Z. Z.; Wang, Y. P.; Wang, X. R.

2002-03-01

For the ballistic quantum transport, the conductance of one channel is quantized to a value of 2e^2/h described by the Landauer formula. In the presence of defects, electrons will be scattered by these defects. Thus the conductance will deviate from the values of the quantized conductance. We show that an anti-resonance scattering can occur when an extra defect level is introduced into a conduction band. At the anti-resonance scattering, exact one quantum conductance is destroyed. The conductance takes a non-zero value when the Fermi energy is away from the anti-resonance scattering. The result is consistent with recent numerical calculations given by H. J. Choi et al. (Phys. Rev. Lett. 84, 2917(2000)) and P. L. McEuen et al. (Phys. Rev. Lett. 83, 5098(1999)).

High-energy-resolution diced spherical quartz analyzers for resonant inelastic X-ray scattering

DOE PAGES

Said, Ayman H.; Gog, Thomas; Wieczorek, Michael; ...

2018-02-15

A novel diced spherical quartz analyzer for use in resonant inelastic X-ray scattering (RIXS) is introduced, achieving an unprecedented energy resolution of 10.53 meV at the IrL 3absorption edge (11.215 keV). In this work the fabrication process and the characterization of the analyzer are presented, and an example of a RIXS spectrum of magnetic excitations in a Sr 3Ir 2O 7sample is shown.

Diabetes, Insulin Resistance, and Dementia Among HIV-1–Infected Patients

PubMed Central

Shikuma, Cecilia M.; Shiramizu, Bruce T.; Williams, Andrew E.; Watters, Michael R.; Poff, Pamela W.; Grove, John S.; Selnes, Ola A.; Sacktor, Ned C.

2006-01-01

Objectives: Metabolic complications have been associated with HIV-1 infection and with long-term use of antiretroviral (ARV) medications. In some studies, such complications have been linked to cardiovascular events, yet limited data exist concerning metabolic complications and dementia. The objective of this study was to examine the relationship between HIV-associated dementia (HAD) and diabetes among patients with HIV-1 infection. Design: Cross-sectional analysis of entry data for a longitudinal cohort study. Methods: A total of 203 participants who were enrolled in the Hawaii Aging with HIV Cohort between October 2001 and November 2003 served as the study population. Research case definitions of HAD were determined in consensus conferences by a panel that included neurologists, neuropsychologists, and a geriatrician. Diabetes was determined by self-report or a fasting glucose level >125 mg/dL. Results: Participants' ages ranged between 20–76 years at enrollment with approximately one-half aged ≥50 years. After adjustment for important covariates including age, education, ethnicity, CD4 lymphocyte count, duration of HIV infection, and protease inhibitor–based ARV therapy, we found a statistically significant association of diabetes with HAD (odds ratio 5.43, 1.66–17.70). A significant association remained after adjustment for other vascular risk factors. Among participants without diabetes, fasting glucose levels were higher with increasing impairment category. Conclusions: Within the Hawaii Aging with HIV Cohort, a longitudinal study enriched with older HIV-1–infected individuals, diabetes is associated with prevalent dementia. This finding is not fully explained by age or coexisting vascular risk factors. Evaluation of underlying mechanisms is warranted. PMID:15608521

Molecular cloning and characterization of the MsHSP17.7 gene from Medicago sativa L.

PubMed

Li, Zhen-Yi; Long, Rui-Cai; Zhang, Tie-Jun; Yang, Qing-Chuan; Kang, Jun-Mei

2016-08-01

Heat shock proteins (HSPs) are ubiquitous protective proteins that play crucial roles in plant development and adaptation to stress, and the aim of this study is to characterize the HSP gene in alfalfa. Here we isolated a small heat shock protein gene (MsHSP17.7) from alfalfa by homology-based cloning. MsHSP17.7 contains a 477-bp open reading frame and encodes a protein of 17.70-kDa. The amino acid sequence shares high identity with MtHSP (93.98 %), PsHSP17.1 (83.13 %), GmHSP17.9 (74.10 %) and SlHSP17.6 (79.25 %). Phylogenetic analysis revealed that MsHSP17.7 belongs to the group of cytosolic class II small heat shock proteins (sHSP), and likely localizes to the cytoplasm. Quantitative RT-PCR indicated that MsHSP17.7 was induced by heat shock, high salinity, peroxide and drought stress. Prokaryotic expression indicated that the salt and peroxide tolerance of Escherichia coli was remarkably enhanced. Transgenic Arabidopsis plants overexpressing MsHSP17.7 exhibited increased root length of transgenic Arabidopsis lines under salt stress compared to the wild-type line. The malondialdehyde (MDA) levels in the transgenic lines were significantly lower than in wild-type, although proline levels were similar between transgenic and wild-type lines. MsHSP17.7 was induced by heat shock, high salinity, oxidative stress and drought stress. Overexpression analysis suggests that MsHSP17.7 might play a key role in response to high salinity stress.

Runoff of small rocky headwater catchments: Field observations and hydrological modeling

NASA Astrophysics Data System (ADS)

Gregoretti, C.; Degetto, M.; Bernard, M.; Crucil, G.; Pimazzoni, A.; De Vido, G.; Berti, M.; Simoni, A.; Lanzoni, S.

2016-10-01

In dolomitic headwater catchments, intense rainstorms of short duration produce runoff discharges that often trigger debris flows on the scree slopes at the base of rock cliffs. In order to measure these discharges, we placed a measuring facility at the outlet (elevation 1770 m a.s.l.) of a small, rocky headwater catchment (area ˜0.032 km2, average slope ˜320%) located in the Venetian Dolomites (North Eastern Italian Alps). The facility consists of an approximately rectangular basin, ending with a sharp-crested weir. Six runoff events were recorded in the period 2011-2014, providing a unique opportunity for characterizing the hydrological response of the catchment. The measured hydrographs display impulsive shapes, with an abrupt raise up to the peak, followed by a rapidly decreasing tail, until a nearly constant plateau is eventually reached. This behavior can be simulated by means of a distributed hydrological model if the excess rainfall is determined accurately. We show that using the Soil Conservation Service Curve-Number (SCS-CN) method and assuming a constant routing velocity invariably results in an underestimated peak flow and a delayed peak time. A satisfactory prediction of the impulsive hydrograph shape, including peak value and timing, is obtained only by combining the SCS-CN procedure with a simplified version of the Horton equation, and simulating runoff routing along the channel network through a matched diffusivity kinematic wave model. The robustness of the proposed methodology is tested through a comparison between simulated and observed timings of runoff or debris flow occurrence in two neighboring alpine basins.

Reactive Resonances in N+N2 Exchange Reaction

NASA Technical Reports Server (NTRS)

Wang, Dunyou; Huo, Winifred M.; Dateo, Christopher E.; Schwenke, David W.; Stallcop, James R.

2003-01-01

Rich reactive resonances are found in a 3D quantum dynamics study of the N + N2 exchange reaction using a recently developed ab initio potential energy surface. This surface is characterized by a feature in the interaction region called Lake Eyring , that is, two symmetric transition states with a shallow minimum between them. An L2 analysis of the quasibound states associated with the shallow minimum confirms that the quasibound states associated with oscillations in all three degrees of freedom in Lake Eyring are responsible for the reactive resonances in the state-to-state reaction probabilities. The quasibound states, mostly the bending motions, give rise to strong reasonance peaks, whereas other motions contribute to the bumps and shoulders in the resonance structure. The initial state reaction probability further proves that the bending motions are the dominating factors of the reaction probability and have longer life times than the stretching motions. This is the first observation of reactive resonances from a "Lake Eyring" feature in a potential energy surface.

Iron overload in a teenager with xerocytosis: the importance of nuclear magnetic resonance imaging.

PubMed

Assis, Reijâne Alves de; Kassab, Carolina; Seguro, Fernanda Salles; Costa, Fernando Ferreira; Silveira, Paulo Augusto Achucarro; Wood, John; Hamerschlak, Nelson

2013-12-01

To report a case of iron overload secondary to xerocytosis, a rare disease in a teenager, diagnosed, by T2* magnetic resonance imaging. We report the case of a symptomatic patient with xerocytosis, a ferritin level of 350ng/mL and a significant cardiac iron overload. She was diagnosed by T2* magnetic resonance imaging and received chelation therapy Ektacytometric analysis confirmed the diagnosis of hereditary xerocytosis. Subsequent T2* magnetic resonance imaging demonstrated complete resolution of the iron overload in various organs, as a new echocardiography revealed a complete resolution of previous cardiac alterations. The patient remains in chelation therapy. Xerocytosis is a rare autosomal dominant genetic disorder characterized by dehydrated stomatocytosis. The patient may present with intense fatigue and iron overload. We suggest the regular use of T2* magnetic resonance imaging for the diagnosis and control of the response to iron chelation in xerocytosis, and we believe it can be used also in other hemolytic anemia requiring transfusions.

Off-resonance saturation magnetic resonance imaging of superparamagnetic polymeric micelles.

PubMed

Khemtong, Chalermchai; Kessinger, Chase W; Togao, Osamu; Ren, Jimin; Takahashi, Masaya; Sherry, A Dean; Gao, Jinming

2009-01-01

An off-resonance saturation (ORS) method was used for magnetic resonance imaging of superparamagnetic polymeric micelles (SPPM). SPPM was produced by encapsulating a cluster of magnetite nanoparticles (9.9+/-0.4 nm in diameter) in poly(ethylene glycol)-b-poly(D,L-lactide) (PEG-PLA) copolymer micelles (micelle diameter: 60+/-9 nm). In ORS MRI, a selective radiofrequency (RF) pulse was applied at an off-resonance position (0-50 ppm) from the bulk water signal, and the SPPM particles were visualized by the contrast on a division image constructed from two images acquired with and without pre-saturation. Here, the effects of saturation offset frequencies, saturation durations, and RF powers on ORS contrasts were investigated as these parameters are critical for optimization of ORS MRI for in vivo imaging applications. The ability to turn "ON" and "OFF" ORS contrast of SPPM solutions permits for an accurate image subtraction and a contrast enhancement to visualize SPPM probes for in vivo imaging of cancer.

Optical immunosensors for detection of Listeria monocytogenes and Salmonella enteritidis from food

NASA Astrophysics Data System (ADS)

Bhunia, Arun K.; Geng, Tao; Lathrop, Amanda; Valadez, Angela; Morgan, Mark T.

2004-03-01

Listeria monocytogenes and Salmonella are two major foodborne pathogens of significant concern. Two optical evanescent wave immunosensors were evaluated for detection: Antibody-coupled fiber-optic biosensor and a surface plasmon resonant (SPR) immunosensor. In the fiber-optic sensor, polyclonal antibodies for the test organisms were immobilized on polystyrene fiber wave -guides using streptavidin - biotin chemistry. Cyanine 5 -labeled monoclonal antibodies C11E9 (for L. monocytogenes) and SF-11 (for Salmonella Enteritidis) were used to generate a specific fluorescent signal. Signal acquisition was performed by launching a laser-light (635 nm) from an Analyte-2000. This immunosensor was able to detect 103 - 109 cfu/ml of L. monocytogenes or 106-109 cfu/ml of Salmonella Enteritidis and the assays were conducted at near real-time with results obtained within one hour of sampling. The assays were specific and showed signal even in the presence of other microorganisms such as E. coli, Enterococcus faecalis or Salmonella Typhimurium. In the SPR system, IAsys instrument (resonant mirror sensor) was used. Monoclonal antibody-C11E9 was directly immobilized onto a carboxylate cuvette. Whole Listeria cells at various concentrations did not yield any signal while surface protein extracts did. Crude protein extracts from L. monocytogenes and L. innocua had average binding responses of around 150 arc sec (0.25 ng/mm2), which was significantly different from L. grayi, L. ivanovii, or L. welshimeri with average responses of <48 arc sec. Both fiber-optic and SPR sensors show promise in near real-time detection of foodborne L. monocytogenes and Salmonella Enteritidis.

Japanese and English Sentence Reading Comprehension and Writing Systems: An fMRI Study of First and Second Language Effects on Brain Activation

ERIC Educational Resources Information Center

Buchweitz, Augusto; Mason, Robert A.; Hasegawa, Mihoko; Just, Marcel A.

2009-01-01

Functional magnetic resonance imaging (fMRI) was used to compare brain activation from native Japanese (L1) readers reading hiragana (syllabic) and kanji (logographic) sentences, and English as a second language (L2). Kanji showed more activation than hiragana in right-hemisphere occipito-temporal lobe areas associated with visuospatial…

Bibliography of Soviet Laser Developments, Number 55. September-October 1981.

DTIC Science & Technology

1983-01-01

Boldeskul , I.Ye., and A.Ye. Boldeskul (0). Fluorescence and resonant R-amanspctra1 probes in studies on the dynamics of biological and micellar...AKAYEV A 45 BOLDESKUL I YE 72 AKHMANOV S A 87 PAPADZHAN YE 1 79 BOLGAROV L N 11 AKHMEDZHANOV I M 24 BABARSKOV YE V 84 BOL’SHOV L A 84 AKHSAKHALYAN A D

Syntax in a Native Language Still Continues to Develop in Adults: Honorification Judgment in Japanese

ERIC Educational Resources Information Center

Momo, Kanako; Sakai, Hiromu; Sakai, Kuniyoshi L.

2008-01-01

Native languages (L1s) are tacitly assumed to be complete and stable in adults. Here we report an unexpected individual variation in judgment of L1 regarding Japanese sentences including honorification, and further clarify its neural basis with functional magnetic resonance imaging (fMRI). By contrasting an honorification judgment task with a…

On the possibility to detect multipolar order in URu 2 Si 2 by the electric quadrupolar transition of resonant elastic x-ray scattering

DOE PAGES

Wang, Y. L.; Fabbris, G.; Meyers, D.; ...

2017-08-30

Resonant elastic x-ray scattering is a powerful technique for measuring multipolar order parameters. In this paper, we theoretically and experimentally study the possibility of using this technique to detect the proposed multipolar order parameters in URu 2 Si 2 at the U- L 3 edge with the electric quadrupolar transition. Based on an atomic model, we calculate the azimuthal dependence of the quadrupolar transition at the U- L 3 edge. Our results illustrate the potential of this technique for distinguishing different multipolar order parameters. We then perform experiments on ultraclean single crystals of URu 2 Si 2 at the U-more » L 3 edge to search for the predicted signal, but do not detect any indications of multipolar moments within the experimental uncertainty. We also theoretically estimate the orders of magnitude of the cross section and the expected count rate of the quadrupolar transition and compare them to the dipolar transitions at the U- M 4 and U- L 3 edges, clarifying the difficulty in detecting higher order multipolar order parameters in URu 2 Si 2 in the current experimental setup.« less

Aircraft Hydraulic Systems Dynamic Analysis

DTIC Science & Technology

1977-10-01

WHEQUT) for a Quincke tube resonator was revised. A similar subroutine was developed to simulate a hydraulic syscem acoustic filter available commer...input datt’l. Tlhe’ .il l t ’p. ol ý", nel-, r , ’li l t io (11 WAý: alq I SO ij•jI Ld t 0 t l• 11 ’ W11 I’ ( Quincke tube) subroutine. With these...studying pump hanger torque, precompression, decompression WHEQUT Subroutine 1) Revised, made corrections to, and ran Quincke tube subroutine (WHEQUT) b

Acoustic Streaming and Microparticle Enrichment within a Microliter Droplet Using a Lamb-Wave Resonator Array

NASA Astrophysics Data System (ADS)

Zhang, Hongxiang; Tang, Zifan; Wang, Zhan; Pan, Shuting; Han, Ziyu; Sun, Chongling; Zhang, Menglun; Duan, Xuexin; Pang, Wei

2018-06-01

We report the nonlinear acoustic streaming effect and the fast manipulation of microparticles by microelectromechanical Lamb-wave resonators in a microliter droplet. The device, consisting of four Lamb-wave resonators on a silicon die, generates cylindrical traveling waves in a liquid and efficiently drives nine horizontal vortices within a 1 -μ l droplet; the performance of the device coincides with the numerical model prediction. Experimentally, the particles are enriched at the stagnation center of the main vortex on the free surface of the droplet in open space without microfluidic channels. In addition, the trajectories of the particles in the droplet can be controlled by the excitation power.

Search for Resonant WW and WZ Production in pp̄ Collisions at √s=1.96 TeV

DOE PAGES

Abazov, V. M.; Abbott, B.; Acharya, B. S.; ...

2011-06-29

We search for resonant WW or WZ production by using up to 5.4 fb⁻¹ of integrated luminosity collected by the D0 experiment in run II of the Fermilab Tevatron Collider. The data are consistent with the standard model background expectation, and we set limits on a resonance mass by using the sequential standard model W' boson and the Randall-Sundrum model graviton G as benchmarks. We exclude a sequential standard model W' boson in the mass range 180–690 GeV and a Randall-Sundrum graviton in the range 300–754 GeV at 95% C.L.

Adjustable low frequency and broadband metamaterial absorber based on magnetic rubber plate and cross resonator

NASA Astrophysics Data System (ADS)

Cheng, Yongzhi; Nie, Yan; Wang, Xian; Gong, Rongzhou

2014-02-01

In this paper, the magnetic rubber plate absorber (MRPA) and metamaterial absorber (MA) based on MRP substrate were proposed and studied numerically and experimentally. Based on the characteristic of L-C resonances, experimental results show that the MA composed of cross resonator (CR) embedded single layer MRP could be adjustable easily by changing the wire length and width of CR structure and MRP thickness. Finally, experimental results show that the MA composed of CR-embedded two layers MRP with the total thickness of 2.42 mm exhibit a -10 dB absorption bandwidth from 1.65 GHz to 3.7 GHz, which is 1.86 times wider than the same thickness MRPA.

Contrast-enhanced magnetic resonance angiography: first-pass arterial enhancement as a function of gadolinium-chelate concentration, and the saline chaser volume and injection rate.

PubMed

Husarik, Daniela B; Bashir, Mustafa R; Weber, Paul W; Nichols, Eli B; Howle, Laurens E; Merkle, Elmar M; Nelson, Rendon C

2012-02-01

To evaluate the effect of the contrast medium (CM) concentration and the saline chaser volume and injection rate on first-pass aortic enhancement characteristics in contrast-enhanced magnetic resonance angiography using a physiologic flow phantom. Imaging was performed on a 3.0-T magnetic resonance system (MAGNETOM Trio, Siemens Healthcare Solutions, Inc, Erlangen, Germany) using a 2-dimensional fast low angle shot T1-weighted sequence (repetition time, 500 milliseconds; echo time, 1.23 milliseconds; flip angle, 8 degrees; 1 frame/s × 60 seconds). The following CM concentrations injected at 2 mL/s were used with 3 different contrast agents (gadolinium [Gd]-BOPTA, Gd-HP-DO3A, Gd-DTPA): 20 mL of undiluted CM (100%) and 80%, 40%, 20%, 10%, 5%, and 2.5% of the full amount, all diluted in saline to a volume of 20 mL to ensure equal bolus volume. The CM was followed by saline chasers of 20 to 60 mL injected at 2 mL/s and 6 mL/s. Aortic signal intensity (SI) was measured, and normalized SI versus time (SI/Tn) curves were generated. The maximal SI (SI(max)), bolus length, and areas under the SI/Tn curve were calculated. Decreasing the CM concentration from 100% to 40% resulted in a decrease of SI(max) to 86.1% (mean). Further decreasing the CM concentration to 2.5% decreased SI(max) to 5.1% (mean). Altering the saline chaser volume had no significant effect on SI(max). Increasing the saline chaser injection rate had little effect (mean increase, 2.2%) on SI(max) when using ≥40% of CM. There was a larger effect (mean increase, 19.6%) when ≤20% of CM were used. Bolus time length was significantly shorter (P < 0.001), and area under the SI/T(n) curve was significantly smaller (P < 0.01) for the CM protocols followed by a saline chaser injected at 6 mL/s compared with a saline chaser injected at 2 mL/s. With 40% of CM and a fast saline chaser, SImax close to that with undiluted CM can be achieved. An increased saline chaser injection rate has a more pronounced effect on aortic enhancement characteristics at lower CM concentrations than at higher CM concentrations.

Sensitivity enhancement of traveling wave MRI using free local resonators: an experimental demonstration.

PubMed

Zhang, Xiaoliang

2017-04-01

Traveling wave MR uses the far fields in signal excitation and reception, therefore its acquisition efficiency is low in contrast to the conventional near field magnetic resonance (MR). Here we show a simple and efficient method based on the local resonator to improving sensitivity of traveling wave MR technique. The proposed method utilizes a standalone or free local resonator to amplify the radio frequency magnetic fields in the interested target. The resonators have no wire connections to the MR system and thus can be conveniently placed to any place around imaging simples. A rectangular loop L/C resonator to be used as the free local resonator was tuned to the proton Larmor frequency at 7T. Traveling wave MR experiments with and without the wireless free local resonator were performed on a living rat using a 7T whole body MR scanner. The signal-to-noise ratio (SNR) or sensitivity of the images acquired was compared and evaluated. In vivo 7T imaging results show that traveling wave MR with a wireless free local resonator placed near the head of a living rat achieves at least 10-fold SNR gain over the images acquired on the same rat using conventional traveling wave MR method, i.e. imaging with no free local resonators. The proposed free local resonator technique is able to enhance the MR sensitivity and acquisition efficiency of traveling wave MR at ultrahigh fields in vivo . This method can be a simple solution to alleviating low sensitivity problem of traveling wave MRI.

Suppression of Alfvénic modes through modification of the fast ion distribution

NASA Astrophysics Data System (ADS)

Fredrickson, Eric

2017-10-01

Experiments on NSTX-U have shown for the first time that small amounts of high pitch-angle, low ρL beam ions can strongly suppress the counter-propagating Global Alfvén Eigenmodes (GAE) [1]. GAE have been implicated in the redistribution of fast ions and modification of the electron power balance in previous experiments on NSTX. The ability to predict the stability of Alfvén modes, and development of methods to control them, is important for fusion reactors like ITER, which like NSTX, will be heated with a large population of non-thermal, super-Alfvénic ions (unlike the normal operation of conventional tokamaks). The suppression of the GAE by adding a small population of high-pitch resonant fast ions is qualitatively consistent with an analytic model of the Doppler-shifted ion-cyclotron resonance drive responsible for GAE instability [2]. The model predicts that fast ions with k⊥ρL <1.9 are stabilizing, which is in good agreement with the experimental observations. A quantitative analysis was done using the HYM stability code [3] of one of the nearly 100 identified examples of GAE suppression. The simulations find remarkable agreement with the observed mode numbers and frequencies of the unstable GAE prior to suppression. Adding the population of high pitch-angle, low ρL beam ions to the HYM fast ion distribution function predicts complete suppression of the GAE. TRANSP/NUBEAM calculations for the example analyzed with HYM suggest that the additional beam source increases the population of resonant fast ions with k⊥ρL <1.9 by roughly a factor of four. Work supported by U.S. DOE Contract DE-AC02-09CH11466.

Structure and Interactions of the Human Programmed Cell Death 1 Receptor*

PubMed Central

Cheng, Xiaoxiao; Veverka, Vaclav; Radhakrishnan, Anand; Waters, Lorna C.; Muskett, Frederick W.; Morgan, Sara H.; Huo, Jiandong; Yu, Chao; Evans, Edward J.; Leslie, Alasdair J.; Griffiths, Meryn; Stubberfield, Colin; Griffin, Robert; Henry, Alistair J.; Jansson, Andreas; Ladbury, John E.; Ikemizu, Shinji; Carr, Mark D.; Davis, Simon J.

2013-01-01

PD-1, a receptor expressed by T cells, B cells, and monocytes, is a potent regulator of immune responses and a promising therapeutic target. The structure and interactions of human PD-1 are, however, incompletely characterized. We present the solution nuclear magnetic resonance (NMR)-based structure of the human PD-1 extracellular region and detailed analyses of its interactions with its ligands, PD-L1 and PD-L2. PD-1 has typical immunoglobulin superfamily topology but differs at the edge of the GFCC′ sheet, which is flexible and completely lacks a C″ strand. Changes in PD-1 backbone NMR signals induced by ligand binding suggest that, whereas binding is centered on the GFCC′ sheet, PD-1 is engaged by its two ligands differently and in ways incompletely explained by crystal structures of mouse PD-1·ligand complexes. The affinities of these interactions and that of PD-L1 with the costimulatory protein B7-1, measured using surface plasmon resonance, are significantly weaker than expected. The 3–4-fold greater affinity of PD-L2 versus PD-L1 for human PD-1 is principally due to the 3-fold smaller dissociation rate for PD-L2 binding. Isothermal titration calorimetry revealed that the PD-1/PD-L1 interaction is entropically driven, whereas PD-1/PD-L2 binding has a large enthalpic component. Mathematical simulations based on the biophysical data and quantitative expression data suggest an unexpectedly limited contribution of PD-L2 to PD-1 ligation during interactions of activated T cells with antigen-presenting cells. These findings provide a rigorous structural and biophysical framework for interpreting the important functions of PD-1 and reveal that potent inhibitory signaling can be initiated by weakly interacting receptors. PMID:23417675

Quantitative and simultaneous non-invasive measurement of skin hydration and sebum levels

PubMed Central

Ezerskaia, Anna; Pereira, S. F.; Urbach, H. Paul; Verhagen, Rieko; Varghese, Babu

2016-01-01

We report a method on quantitative and simultaneous non-contact in-vivo hydration and sebum measurements of the skin using an infrared optical spectroscopic set-up. The method utilizes differential detection with three wavelengths 1720, 1750, and 1770 nm, corresponding to the lipid vibrational bands that lay “in between” the prominent water absorption bands. We have used an emulsifier containing hydro- and lipophilic components to mix water and sebum in various volume fractions which was applied to the skin to mimic different oily-dry skin conditions. We also measured the skin sebum and hydration values on the forehead under natural conditions and its variations to external stimuli. Good agreement was found between our experimental results and reference values measured using conventional biophysical methods such as Corneometer and Sebumeter. PMID:27375946

"Franklin: Science, Politics and France"

NASA Astrophysics Data System (ADS)

McClellan, James E., III

2003-04-01

This presentation traces Benjamin Franklin's career as a "civic scientist" in Old-Regime France. It outlines the initial - and not always positive - reception of Franklin's work on electricity by the community of French scientists in the 1750s. It sketches Franklin's subsequent elevation into the pantheon of French Enlightenment heros, and it details his work as a "civic scientist" while American envoy to France in the 1770s and 1780s, notably his service on the government-sponsored commissions that repudiated the scientific and medical claims of Franz Anton Mesmer. This presentation concludes by examining a few features of Franklin's career that are not completely congruent with our notion of what a "civic scientist" might be, a contrast that is intended to illuminate both Franklin and the concept of "civic scientist."

[Sir Humphry Davy, the discoverer of anesthetic action of nitrous oxide--Davy and poets of British Romanticism and inhalation of laughing gas by his friends].

PubMed

Fujita, T

1998-01-01

In "Dove Cottage", the old house of the poet laureate William Wordsworth (1770-1850) in Grasmere, England, there is a portrait of Sir Humphry Davy (1778-1829). In 1804, Wordsworth invited his young friend to his home. Davy's works in the field of chemistry are well known. Interestingly enough, once he wished he could be a poet. His future seemed to be prosperous and delightful. He was highly evaluated by Robert Southey, poet laureate. But he has chosen the way of chemist. The author found some facts from literatures and received some information by courtesy of the Wordsworth Trust, Centre for British Romanticism. Davy's life and his works were introduced chronologically.

Rapid and quantitative chemical exchange saturation transfer (CEST) imaging with magnetic resonance fingerprinting (MRF).

PubMed

Cohen, Ouri; Huang, Shuning; McMahon, Michael T; Rosen, Matthew S; Farrar, Christian T

2018-05-13

To develop a fast magnetic resonance fingerprinting (MRF) method for quantitative chemical exchange saturation transfer (CEST) imaging. We implemented a CEST-MRF method to quantify the chemical exchange rate and volume fraction of the N α -amine protons of L-arginine (L-Arg) phantoms and the amide and semi-solid exchangeable protons of in vivo rat brain tissue. L-Arg phantoms were made with different concentrations (25-100 mM) and pH (pH 4-6). The MRF acquisition schedule varied the saturation power randomly for 30 iterations (phantom: 0-6 μT; in vivo: 0-4 μT) with a total acquisition time of ≤2 min. The signal trajectories were pattern-matched to a large dictionary of signal trajectories simulated using the Bloch-McConnell equations for different combinations of exchange rate, exchangeable proton volume fraction, and water T 1 and T 2 relaxation times. The chemical exchange rates of the N α -amine protons of L-Arg were significantly (P < 0.0001) correlated with the rates measured with the quantitation of exchange using saturation power method. Similarly, the L-Arg concentrations determined using MRF were significantly (P < 0.0001) correlated with the known concentrations. The pH dependence of the exchange rate was well fit (R 2  = 0.9186) by a base catalyzed exchange model. The amide proton exchange rate measured in rat brain cortex (34.8 ± 11.7 Hz) was in good agreement with that measured previously with the water exchange spectroscopy method (28.6 ± 7.4 Hz). The semi-solid proton volume fraction was elevated in white (12.2 ± 1.7%) compared to gray (8.1 ± 1.1%) matter brain regions in agreement with previous magnetization transfer studies. CEST-MRF provides a method for fast, quantitative CEST imaging. © 2018 International Society for Magnetic Resonance in Medicine.

Interaction of Rydberg atoms in circular states with the alkaline-earth Ca(4s{sup 2}) and Sr(5s{sup 2}) atoms

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mironchuk, E. S.; Narits, A. A.; Lebedev, V. S., E-mail: vlebedev@sci.lebedev.ru

2015-11-15

The resonant mechanism of interaction of alkaline-earth atoms having a low electron affinity to Rydberg atoms in circular (l = vertical bar m vertical bar = n–1) and near-circular states has been studied. To describe the dynamics of resonant processes accompanied by nonadiabatic transitions between ionic and Rydberg covalent terms of a quasimolecule, an approach based on the integration of coupled equations for the probability amplitudes has been developed taking into account the possibility of the decay of an anion in the Coulomb field of the positive ionic core of a highly excited atom. The approach involves the specific featuresmore » of the problem associated with the structure of the wavefunction of a Rydberg electron in states with high orbital angular momenta l ∼ n–1. This approach provides a much more accurate description of the dynamics of electronic transitions at collisions between atoms than that within the modified semiclassical Landau–Zener model. In addition, this approach makes it possible to effectively take into account many channels of the problem. The cross sections for resonant quenching of Rydberg states of the Li(nlm) atom with given principal n, orbital l = n–1, and magnetic m quantum numbers at thermal collisions with the Ca(4s{sup 2}) and Sr(5s{sup 2}) atoms have been calculated. The dependences of the results on n, m, and angle α between the relative velocity of the atoms and the normal to the plane of the orbit of the Rydberg electron have been obtained. The influence of orientational effects on the efficiency of the collisional destruction of circular and near-circular states has been studied. The results indicate a higher stability of such states to their perturbations by neutral particles as compared to usually studied nl states with low values of l (l ≪ n)« less

A 500 year seasonally resolved δ18O and δ13C, layer thickness and calcite fabric record from a speleothem deposited in equilibrium of the Han-sur-Lesse cave, Belgium

NASA Astrophysics Data System (ADS)

Van Rampelbergh, M.; Verheyden, S.; Allan, M.; Quinif, Y.; Cheng, H.; Edwards, L.; Keppens, E.; Claeys, P.

2014-10-01

Speleothem δ18O and δ13C signals have already proven to enable climate reconstructions at high resolution. However, seasonally resolved speleothem records are still scarce and often difficult to interpret in terms of climate due to the multitude of factors that can affect the proxy signals. In this paper, a fast growing (up to 2 mm yr-1) seasonally laminated speleothem from the Han-sur-Lesse cave (Belgium) is analyzed for its δ18O and δ13C values, layer thickness and changes in calcite fabric. The studied part of the speleothem covers the most recent 500 years as indicated by layer counting and confirmed by 20 U/Th-ages. Epikarst recharge occurs mainly in winter and lesser during spring and fall. a good correlation can be established between lower winter temperatures and lower winter precipitation (DJF) based on the measured data by the Belgian meteorological institute since 1833 indicating that a dry winter is also a cold winter. Colder and dryer winters cause lower winter recharge and generally drier conditions in the cave. Lower winter recharge decreases the amount of isotopically light (δ18O) winter precipitation added to the epikarst in comparison to the heavier spring and fall waters, which leads to a net increase in δ18O value of the water in the epikarst. Increased δ18O values in the Proserpine are consequently interpreted to reflect colder and dryer winters. Higher δ13C signals are interpreted to reflect increased prior calcite precipitation (PCP) due to colder and dryer winters, when recharge is lower. Thinner layers and darker calcite relate to slower growth and occur when drip rates are low and when the drip water calcium ion concentration is low due to increased PCP, both caused by lower recharge during periods with colder and dryer winters. Exceptionally cold and dry winters cause the drip discharge to decrease under a certain threshold value inducing anomalies in the measured proxy records. Such anomalies occur from 1565 to 1610, from 1770 to 1800, from 1810 to 1860 and from 1880 to 1895 and correspond with exceptionally cold periods in proxy-based, historical and instrumental records and may relate to different factors such as negative winter NAO phases, lower solar irradiance and/or volcanic eruptions. When the discharge threshold is not reached, lower amplitude variations are observed such as between 1479 and 1565 and between 1730 and 1770 with two periods of relatively warmer and wetter winters. Between 1610 and 1730 a period of relatively cooler and dryer winters occurs and may relate to a decrease in solar irradiance during the Maunder Minimum (1640-1714). Seasonal δ18O variations indicate a 2.5 °C seasonality in cave air temperature during the two periods with warmer and wetter winters (1479-1565 and 1730-1770), and correspond to the cave air temperature seasonality observed today. a smaller 1.5 °C seasonality in cave air temperature occurs during the interval with colder and wetter winters between 1610 and 1730 and suggests colder summers. The δ13C seasonal changes suggest that the seasonality in discharge was lower than the one observed today with a short interval of increased seasonality between 1600 and 1660 reflecting stronger summer PCP-effects due to decreased winter recharge.

Connection of the Late Paleolithic archaeological sites of the Chuya depression with geological evidence of existence of the Late Pleistocene ice-dammed lakes

NASA Astrophysics Data System (ADS)

Agatova, A. R.; Nepop, R. K.

2017-07-01

The complexity of the age dating of the Pleistocene ice-dammed paleolakes in the Altai Mountains is a reason why geologists consider the Early Paleolithic archaeological sites as an independent age marker for dating geological objects. However, in order to use these sites for paleogeographic reconstructions, their locations, the character of stratification, and the age of stone artifacts need to be comprehensively studied. We investigate 20 Late Paleolithic archaeological sites discovered in the Chuya depression of the Russian Altai (Altai Mountains) with the aim of their possible use for reconstructions of the period of development of the Kurai-Chuya glacio-limnosystem in the Late Neopleistocene. The results of our investigation show that it is improper to use the Paleolithic archaeological sites for the dating of the existence period and the draining time of ice-dammed lakes of the Chuya Depression in the modern period of their study owing to a lack of quantitative age estimates, a wide age range of possible existence of these sites, possible redeposition of the majority of artifacts, and their surface occurrence. It is established that all stratified sites where cultural layers are expected to be dated in the future lie above the uppermost and well-expressed paleolake level (2100 m a.s.l.). Accordingly, there are no grounds to determine the existence time of shallower paleolakes. Since the whole stone material collected below the level of 2100 m a.s.l. is represented by surface finds, it is problematic to use these artifacts for absolute geochronology. The Late Paleolithic Bigdon and Chechketerek sites are of great interest for paleogeographic reconstructions of ice-dammed lakes. The use of iceberg rafting products as cores is evidence that these sites appeared after the draining of a paleolake (2000 m a.s.l.). At this time, the location of these archaeological sites on the slope of the Chuya Depression allows one to assume the existence of a large lake as deep as 250 m synchronously with the above paleolake or later. The location of the lowermost archaeological sites is evidence that a paleolake could have existed at an altitude below 1770 m a.s.l. in the Late Neopleistocene-Early Holocene. The absolute geochronology of the archaeological sites (cultural layers in multilayered sites, split surfaces on dropstones, etc.) can be useful for further reconstructions of the existence time, depths, and a number of ice-dammed lakes in the Kurai-Chuya system of depressions.

Hydrological change during the last 600 years as observed from landscape analysis and historical maps: a case study from the Nete catchment, Campine area, NE-Belgium

NASA Astrophysics Data System (ADS)

Beerten, Koen; Leterme, Bertrand

2015-04-01

Reliably predicting the future state of the hydrological system under transient climate and land use conditions is a major challenge. Hydrological models are usually calibrated and validated for a short time period (e.g. 30 years), for conditions that are similar to today's. In order to test model performance for future (unverifiable) projections, palaeohydrological modelling is first needed to build confidence in model output under different conditions. One of the major challenges of palaeohydrological modelling is the acquisition of verification data that is representative for the past state(s) of the hydrological system. Here, we present the reconstructed evolution of the groundwater table depth over the last six centuries, in a sandy interfluvium (20 km² with altitude varying between 16 m and 28 m a.s.l.) of the Nete catchment. For periods before 1770 AD, the altitude (depth) of blown-out surfaces in the drift sand landscape is used as a proxy for the average highest groundwater level. These surfaces are generally interpreted as the lower limit for wind erosion. Soil profiles investigations where these surfaces are overblown by younger drift sand show that they were created in the time period between ca. 1400 AD and 1600 AD. For younger periods, historical maps were analysed for the presence of surface water features, such as fens (shallow lakes that are groundwater fed in this sandy landscape under temperate climate), marshes and wetlands. The results clearly show declining water levels in the second half of the 19th century, i.e., between 1854 AD and 1909 AD. The decline is most pronounced for the higher areas of the interfluve (drift sand landscape) and becomes less clear towards the floodplains. The amount of groundwater level decline is 1-2 m on average. The cause for the synchronous groundwater level drop seems to be linked to land use and land cover changes during that period. In the time interval between 1854 AD and 1909 AD, the total length of drains increased from 2 km to 25 km, while land cover changed from 80% heathland and almost no trees to only 20% heathland and 50% coniferous forest. Available palaeoclimate records suggest that there is no correlation between groundwater level change and average annual temperature or precipitation. Furthermore, population density seems to be uncorrelated with the observed hydrological changes. Internal consistency checks are performed and found satisfactory. For example, the high groundwater levels predicted by the blown-out surfaces for 1400-1600 AD are confirmed by surface water features on younger historical maps (~1770 AD and ~1850 AD). Indeed, pollen analysis, topographical maps and climate records show that land cover and climate did not change significantly throughout the period 1400 AD to 1850 AD. We conclude that the proposed methods are useful tools to gather verification data (i.e., groundwater table depth) for palaeohydrological modelling in the European sand belt during the last millenium.

Novel Luminescent Probe Based on a Terbium(III) Complex for Hemoglobin Determination

NASA Astrophysics Data System (ADS)

Yegorova, A. V.; Leonenko, I. I.; Aleksandrova, D. I.; Scrypynets, Yu. V.; Antonovich, V. P.; Ukrainets, I. V.

2014-09-01

We have studied the spectral luminescent properties of Tb(III) and Eu(III) complexes with a number of novel derivatives of oxoquinoline-3-carboxylic acid amides (L1-L5 ). We have observed quenching of the luminescence of 1:1 Tb(III)-L1-5 complexes by hemoglobin (Hb), which is explained by resonance energy transfer of electronic excitation from the donor (Tb(III)-L1-5 ) to the acceptor (Hb). Using the novel luminescent probe Tb(III)-L1, we have developed a method for determining Hb in human blood. The calibration Stern-Volmer plot is linear in the Hb concentration range 0.6-36.0 μg/mL, detection limit 0.2 μg/mL (3·10-9 mol/L).

Advances in Components for Active and Passive Airborne Sensors (Progres des Composants pour les Systemes des Detection Active et Passive Aeroportes)

DTIC Science & Technology

1990-09-01

simplest form the modulators are systems. 1) The inter -band absorption edges at operated as non-resonant (single-pass) which the electro-absorption...transitions in -0111- 1,’. three different wavelength bands indicated. It is the NIR inter -band transition which is of interest in this E’l Iwork. 0...quartz crystal resonator is a vector quantity. 12 random vibration at 100 Hz away from the Therefore, the frequency during acceleration carrier. Of

Sideband Spectroscopy and Dispersion Measurement in Microcavities

DTIC Science & Technology

2012-11-07

high coherence, Brillouin microcavity laser on silicon ,” Opt. Express 20, 20170–20180, (2012). 12. T. Herr, K. Hartinger, J. Riemensberger, C. Y...ultrahigh-Q wedge- resonator on a silicon chip,” Nat. Photon. 6, 369–373 (2012). 11. J. Li, H. Lee, T. Chen, and K. J. Vahala, “Characterization of a ...microresonators,” Nat. Photon. 6, 480–487 (2012). 13. I. Grudinin, A . Matsko, and L. Maleki, “ Brillouin lasing with a CaF2 whispering gallery mode resonator,” Phys

Advanced Techniques for Transmutation Compensation of Extrinsic Silicon Detectors.

DTIC Science & Technology

1980-10-01

generally better than 1..2 R . EPR Spectrometer NMicroscopic defect structure is determined by elec- tron paramagnetic resonance (HIlP ) or, as it is more...cnm- monly known, elet ron spin resonance ( I;R . The 1,S R instrument used for th(,se experimnents is -I COllVttiOl1l1 X-band (9 (;ll:) SpectroletoPr...226 75. DLTS electron traps in n-type neutron irra- diated Si as a function of isohronal anneals (100 Hz, th = 1.8 x 1015 n

Frequency Hopping Transceiver Multiplexer

DTIC Science & Technology

1983-03-01

l~o ngth ( method 211) Ile If 19 nose (m Wace em. t amem 0 311c fte s Saa Spray (meto 101. cond. U) nom t 7 o m011 V $h dIVN5k~ WaftIS OCIV16111 ATC...the resonators together to reduce adverse loading is also critical. Figure 5-12 shows two methods of obtaining the desired selectivity. Part A of...this large frequency range required. E.7 CONCLUSIONS It appears that the Helical Resonator with the capacitance bus is the best method available to

Toroidal silicon polarization analyzer for resonant inelastic x-ray scattering

DOE PAGES

Gao, Xuan; Casa, Diego; Kim, Jungho; ...

2016-08-15

Resonant Inelastic X-ray Scattering (RIXS) is a powerful probe for studying electronic excitations in materials. Standard high energy RIXS measurements do not measure the polarization of the scattered x-rays, which is unfortunate since it carries information about the nature and symmetry of the excitations involved in the scattering process. Moreover we report the fabrication of thin Si-based polarization analyzers with a double-concave toroidal surface, useful for L-edge RIXS studies in heavier atoms such as the 5-d transition metals.

Cardiovascular Magnetic Resonance in Cardiology Practice: A Concise Guide to Image Acquisition and Clinical Interpretation.

PubMed

Valbuena-López, Silvia; Hinojar, Rocío; Puntmann, Valentina O

2016-02-01

Cardiovascular magnetic resonance plays an increasingly important role in routine cardiology clinical practice. It is a versatile imaging modality that allows highly accurate, broad and in-depth assessment of cardiac function and structure and provides information on pertinent clinical questions in diseases such as ischemic heart disease, nonischemic cardiomyopathies, and heart failure, as well as allowing unique indications, such as the assessment and quantification of myocardial iron overload or infiltration. Increasing evidence for the role of cardiovascular magnetic resonance, together with the spread of knowledge and skill outside expert centers, has afforded greater access for patients and wider clinical experience. This review provides a snapshot of cardiovascular magnetic resonance in modern clinical practice by linking image acquisition and postprocessing with effective delivery of the clinical meaning. Copyright © 2015 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.

Probing 5 f -state configurations in URu 2 Si 2 with U L III -edge resonant x-ray emission spectroscopy

DOE PAGES

Booth, Corwin H.; Medling, S. A.; Tobin, J. G.; ...

2016-07-15

Resonant x-ray emission spectroscopy (RXES) was employed at the U LIII absorption edge and the L α1 emission line to explore the 5f occupancy, nf, and the degree of 5f-orbital delocalization in the hidden-order compound URu 2Si 2. By comparing to suitable reference materials such as UF 4, UCd 11, and α-U, we conclude that the 5f orbital in URu 2Si 2 is at least partially delocalized with n f=2.87±0.08, and does not change with temperature down to 10 K within the estimated error. These results place further constraints on theoretical explanations of the hidden order, especially those requiring amore » localized f 2 ground state.« less

The analytical application and spectral investigation of DNA-CPB-emodin and sensitive determination of DNA by resonance Rayleigh light scattering technique

NASA Astrophysics Data System (ADS)

Bi, Shuyun; Wang, Yu; Wang, Tianjiao; Pang, Bo; Zhao, Tingting

2013-01-01

A new sensitive DNA probe containing cetylpyridinium bromide (CPB) and emodin (an effective component of Chinese herbal medicine) was developed using the resonance Rayleigh light scattering (RLS) technique. A novel assay was first developed to detect DNA at nanogram level based on the ternary system of DNA-CPB-emodin. The RLS signal of DNA was enhanced remarkably in the presence of emodin-CPB, and the enhanced RLS intensity at 340.0 nm was in direct proportion to DNA concentration in the range of 0.01-2.72 μg mL-1 with a good linear relationship. The detection limit was 1.5 ng mL-1. Three synthetic DNA samples were measured obtaining satisfactory results, the recovery was 97.6-107.3%.

Resonant spin wave excitations in a magnonic crystal cavity

NASA Astrophysics Data System (ADS)

Kumar, N.; Prabhakar, A.

2018-03-01

Spin polarized electric current, injected into permalloy (Py) through a nano contact, exerts a torque on the magnetization. The spin waves (SWs) thus excited propagate radially outward. We propose an antidot magnonic crystal (MC) with a three-hole defect (L3) around the nano contact, designed so that the frequency of the excited SWs, lies in the band gap of the MC. L3 thus acts as a resonant SW cavity. The energy in this magnonic crystal cavity can be tapped by an adjacent MC waveguide (MCW). An analysis of the simulated micromagnetic power spectrum, at the output port of the MCW reveals stable SW oscillations. The quality factor of the device, calculated using the decay method, was estimated as Q > 105 for an injected spin current density of 7 ×1012 A/m2.

Accurate computer-aided quantification of left ventricular parameters: experience in 1555 cardiac magnetic resonance studies from the Framingham Heart Study.

PubMed

Hautvast, Gilion L T F; Salton, Carol J; Chuang, Michael L; Breeuwer, Marcel; O'Donnell, Christopher J; Manning, Warren J

2012-05-01

Quantitative analysis of short-axis functional cardiac magnetic resonance images can be performed using automatic contour detection methods. The resulting myocardial contours must be reviewed and possibly corrected, which can be time-consuming, particularly when performed across all cardiac phases. We quantified the impact of manual contour corrections on both analysis time and quantitative measurements obtained from left ventricular short-axis cine images acquired from 1555 participants of the Framingham Heart Study Offspring cohort using computer-aided contour detection methods. The total analysis time for a single case was 7.6 ± 1.7 min for an average of 221 ± 36 myocardial contours per participant. This included 4.8 ± 1.6 min for manual contour correction of 2% of all automatically detected endocardial contours and 8% of all automatically detected epicardial contours. However, the impact of these corrections on global left ventricular parameters was limited, introducing differences of 0.4 ± 4.1 mL for end-diastolic volume, -0.3 ± 2.9 mL for end-systolic volume, 0.7 ± 3.1 mL for stroke volume, and 0.3 ± 1.8% for ejection fraction. We conclude that left ventricular functional parameters can be obtained under 5 min from short-axis functional cardiac magnetic resonance images using automatic contour detection methods. Manual correction more than doubles analysis time, with minimal impact on left ventricular volumes and ejection fraction. Copyright © 2011 Wiley Periodicals, Inc.

Influence of intense THz radiation on spin state of photoswitchable compound Cu(hfac)2L(Pr).

PubMed

Veber, Sergey L; Fedin, Matvey V; Maryunina, Ksenia Yu; Boldyrev, Kirill N; Sheglov, Mikhail A; Kubarev, Vitaly V; Shevchenko, Oleg A; Vinokurov, Nikolay A; Kulipanov, Gennady N; Sagdeev, Renad Z; Ovcharenko, Victor I; Bagryanskaya, Elena G

2013-02-21

The family of magnetoactive compounds Cu(hfac)(2)L(R) exhibits thermo- and photoswitching phenomena promising for various applications. Photoswitching of the Cu(hfac)(2)L(Pr) compound can be observed at temperatures below 20 K and is accompanied by transition to metastable structural state. Reverse conversion to stable structure could not be induced by light of near-IR-vis-UV regions up to date. The far-IR spectra of metastable and stable structural states are different and show characteristic absorption lines in the range of 170-240 cm(-1). These frequencies are accessible by NovoFEL - high-power THz free-electron laser user facility in Novosibirsk. We investigate selective influence of THz radiation on relaxation processes from metastable to stable structural state, which can be monitored by electron paramagnetic resonance (EPR). For this purpose, the experimental station based on X-band EPR spectrometer has been constructed by the THz beamline of NovoFEL and equipped with multimodal THz waveguide allowing to fed radiation directly into the EPR resonator. It has been found that irradiation of studied compound with high-power THz light causes significant but nondestructive increase of its temperature. Apart from this effect, no resonant influence of THz irradiation on relaxation processes has been observed. The experimental results have been rationalized taking into account vibrational relaxation times of the studied compound. Further experiments based on pulse heating by THz radiation have been proposed.

Hyperon and hyperon resonance properties from charm baryon decays at BABAR

NASA Astrophysics Data System (ADS)

Ziegler, Veronique

This thesis describes studies of hyperons and hyperon resonances produced in charm baryon decays at BABAR. Using two-body decays of the X0c and W0c , it is shown, for the first time, that the spin of the O - is 3/2. The O- analysis procedures are extended to three-body final states and properties of the xi(1690)0 are extracted from a detailed isobar model analysis of the L+c → ΛK¯0K + Dalitz plot. The mass and width values of the xi(1690) 0 are measured with much greater precision than attained previously. The hypothesis that the spin of the xi(1690) resonance is 1/2 yields an excellent description of the data, while spin values 3/2 and 5/2 are disfavored. The Λa0(980)+ decay mode of the L+c is observed for the first time. Similar techniques are then used to study xi(1530)0 production in L+c decay. The spin of the xi(1530) is established for the first time to be 3/2. The existence of an S-wave amplitude in the xi -pi+ system is shown, and its interference with the xi(1530) 0 amplitude provides the first clear demonstration of the Breit-Wigner phase motion expected for the xi(1530). The xi-pi + mass distribution in the vicinity of the xi(1690)0 exhibits interesting structure which may be interpreted as indicating that the xi(1690) has negative parity.