Sample records for l1 norm minimization

  1. Graph cuts via l1 norm minimization.

    PubMed

    Bhusnurmath, Arvind; Taylor, Camillo J

    2008-10-01

    Graph cuts have become an increasingly important tool for solving a number of energy minimization problems in computer vision and other fields. In this paper, the graph cut problem is reformulated as an unconstrained l1 norm minimization that can be solved effectively using interior point methods. This reformulation exposes connections between the graph cuts and other related continuous optimization problems. Eventually the problem is reduced to solving a sequence of sparse linear systems involving the Laplacian of the underlying graph. The proposed procedure exploits the structure of these linear systems in a manner that is easily amenable to parallel implementations. Experimental results obtained by applying the procedure to graphs derived from image processing problems are provided.

  2. Low dose CT reconstruction via L1 norm dictionary learning using alternating minimization algorithm and balancing principle.

    PubMed

    Wu, Junfeng; Dai, Fang; Hu, Gang; Mou, Xuanqin

    2018-04-18

    Excessive radiation exposure in computed tomography (CT) scans increases the chance of developing cancer and has become a major clinical concern. Recently, statistical iterative reconstruction (SIR) with l0-norm dictionary learning regularization has been developed to reconstruct CT images from the low dose and few-view dataset in order to reduce radiation dose. Nonetheless, the sparse regularization term adopted in this approach is l0-norm, which cannot guarantee the global convergence of the proposed algorithm. To address this problem, in this study we introduced the l1-norm dictionary learning penalty into SIR framework for low dose CT image reconstruction, and developed an alternating minimization algorithm to minimize the associated objective function, which transforms CT image reconstruction problem into a sparse coding subproblem and an image updating subproblem. During the image updating process, an efficient model function approach based on balancing principle is applied to choose the regularization parameters. The proposed alternating minimization algorithm was evaluated first using real projection data of a sheep lung CT perfusion and then using numerical simulation based on sheep lung CT image and chest image. Both visual assessment and quantitative comparison using terms of root mean square error (RMSE) and structural similarity (SSIM) index demonstrated that the new image reconstruction algorithm yielded similar performance with l0-norm dictionary learning penalty and outperformed the conventional filtered backprojection (FBP) and total variation (TV) minimization algorithms.

  3. Brain abnormality segmentation based on l1-norm minimization

    NASA Astrophysics Data System (ADS)

    Zeng, Ke; Erus, Guray; Tanwar, Manoj; Davatzikos, Christos

    2014-03-01

    We present a method that uses sparse representations to model the inter-individual variability of healthy anatomy from a limited number of normal medical images. Abnormalities in MR images are then defined as deviations from the normal variation. More precisely, we model an abnormal (pathological) signal y as the superposition of a normal part ~y that can be sparsely represented under an example-based dictionary, and an abnormal part r. Motivated by a dense error correction scheme recently proposed for sparse signal recovery, we use l1- norm minimization to separate ~y and r. We extend the existing framework, which was mainly used on robust face recognition in a discriminative setting, to address challenges of brain image analysis, particularly the high dimensionality and low sample size problem. The dictionary is constructed from local image patches extracted from training images aligned using smooth transformations, together with minor perturbations of those patches. A multi-scale sliding-window scheme is applied to capture anatomical variations ranging from fine and localized to coarser and more global. The statistical significance of the abnormality term r is obtained by comparison to its empirical distribution through cross-validation, and is used to assign an abnormality score to each voxel. In our validation experiments the method is applied for segmenting abnormalities on 2-D slices of FLAIR images, and we obtain segmentation results consistent with the expert-defined masks.

  4. The design of L1-norm visco-acoustic wavefield extrapolators

    NASA Astrophysics Data System (ADS)

    Salam, Syed Abdul; Mousa, Wail A.

    2018-04-01

    Explicit depth frequency-space (f - x) prestack imaging is an attractive mechanism for seismic imaging. To date, the main focus of this method was data migration assuming an acoustic medium, but until now very little work assumed visco-acoustic media. Real seismic data usually suffer from attenuation and dispersion effects. To compensate for attenuation in a visco-acoustic medium, new operators are required. We propose using the L1-norm minimization technique to design visco-acoustic f - x extrapolators. To show the accuracy and compensation of the operators, prestack depth migration is performed on the challenging Marmousi model for both acoustic and visco-acoustic datasets. The final migrated images show that the proposed L1-norm extrapolation results in practically stable and improved resolution of the images.

  5. Experimental/clinical evaluation of EIT image reconstruction with l1 data and image norms

    NASA Astrophysics Data System (ADS)

    Mamatjan, Yasin; Borsic, Andrea; Gürsoy, Doga; Adler, Andy

    2013-04-01

    Electrical impedance tomography (EIT) image reconstruction is ill-posed, and the spatial resolution of reconstructed images is low due to the diffuse propagation of current and limited number of independent measurements. Generally, image reconstruction is formulated using a regularized scheme in which l2 norms are preferred for both the data misfit and image prior terms due to computational convenience which result in smooth solutions. However, recent work on a Primal Dual-Interior Point Method (PDIPM) framework showed its effectiveness in dealing with the minimization problem. l1 norms on data and regularization terms in EIT image reconstruction address both problems of reconstruction with sharp edges and dealing with measurement errors. We aim for a clinical and experimental evaluation of the PDIPM method by selecting scenarios (human lung and dog breathing) with known electrode errors, which require a rigorous regularization and cause the failure of reconstructions with l2 norm. Results demonstrate the applicability of PDIPM algorithms, especially l1 data and regularization norms for clinical applications of EIT showing that l1 solution is not only more robust to measurement errors in clinical setting, but also provides high contrast resolution on organ boundaries.

  6. L 1-2 minimization for exact and stable seismic attenuation compensation

    NASA Astrophysics Data System (ADS)

    Wang, Yufeng; Ma, Xiong; Zhou, Hui; Chen, Yangkang

    2018-06-01

    Frequency-dependent amplitude absorption and phase velocity dispersion are typically linked by the causality-imposed Kramers-Kronig relations, which inevitably degrade the quality of seismic data. Seismic attenuation compensation is an important processing approach for enhancing signal resolution and fidelity, which can be performed on either pre-stack or post-stack data so as to mitigate amplitude absorption and phase dispersion effects resulting from intrinsic anelasticity of subsurface media. Inversion-based compensation with L1 norm constraint, enlightened by the sparsity of the reflectivity series, enjoys better stability over traditional inverse Q filtering. However, constrained L1 minimization serving as the convex relaxation of the literal L0 sparsity count may not give the sparsest solution when the kernel matrix is severely ill conditioned. Recently, non-convex metric for compressed sensing has attracted considerable research interest. In this paper, we propose a nearly unbiased approximation of the vector sparsity, denoted as L1-2 minimization, for exact and stable seismic attenuation compensation. Non-convex penalty function of L1-2 norm can be decomposed into two convex subproblems via difference of convex algorithm, each subproblem can be solved efficiently by alternating direction method of multipliers. The superior performance of the proposed compensation scheme based on L1-2 metric over conventional L1 penalty is further demonstrated by both synthetic and field examples.

  7. Robust L1-norm two-dimensional linear discriminant analysis.

    PubMed

    Li, Chun-Na; Shao, Yuan-Hai; Deng, Nai-Yang

    2015-05-01

    In this paper, we propose an L1-norm two-dimensional linear discriminant analysis (L1-2DLDA) with robust performance. Different from the conventional two-dimensional linear discriminant analysis with L2-norm (L2-2DLDA), where the optimization problem is transferred to a generalized eigenvalue problem, the optimization problem in our L1-2DLDA is solved by a simple justifiable iterative technique, and its convergence is guaranteed. Compared with L2-2DLDA, our L1-2DLDA is more robust to outliers and noises since the L1-norm is used. This is supported by our preliminary experiments on toy example and face datasets, which show the improvement of our L1-2DLDA over L2-2DLDA. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. Linear discriminant analysis based on L1-norm maximization.

    PubMed

    Zhong, Fujin; Zhang, Jiashu

    2013-08-01

    Linear discriminant analysis (LDA) is a well-known dimensionality reduction technique, which is widely used for many purposes. However, conventional LDA is sensitive to outliers because its objective function is based on the distance criterion using L2-norm. This paper proposes a simple but effective robust LDA version based on L1-norm maximization, which learns a set of local optimal projection vectors by maximizing the ratio of the L1-norm-based between-class dispersion and the L1-norm-based within-class dispersion. The proposed method is theoretically proved to be feasible and robust to outliers while overcoming the singular problem of the within-class scatter matrix for conventional LDA. Experiments on artificial datasets, standard classification datasets and three popular image databases demonstrate the efficacy of the proposed method.

  9. Concentration of the L{sub 1}-norm of trigonometric polynomials and entire functions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Malykhin, Yu V; Ryutin, K S

    2014-11-30

    For any sufficiently large n, the minimal measure of a subset of [−π,π] on which some nonzero trigonometric polynomial of order ≤n gains half of the L{sub 1}-norm is shown to be π/(n+1). A similar result for entire functions of exponential type is established. Bibliography: 13 titles.

  10. An L1-norm phase constraint for half-Fourier compressed sensing in 3D MR imaging.

    PubMed

    Li, Guobin; Hennig, Jürgen; Raithel, Esther; Büchert, Martin; Paul, Dominik; Korvink, Jan G; Zaitsev, Maxim

    2015-10-01

    In most half-Fourier imaging methods, explicit phase replacement is used. In combination with parallel imaging, or compressed sensing, half-Fourier reconstruction is usually performed in a separate step. The purpose of this paper is to report that integration of half-Fourier reconstruction into iterative reconstruction minimizes reconstruction errors. The L1-norm phase constraint for half-Fourier imaging proposed in this work is compared with the L2-norm variant of the same algorithm, with several typical half-Fourier reconstruction methods. Half-Fourier imaging with the proposed phase constraint can be seamlessly combined with parallel imaging and compressed sensing to achieve high acceleration factors. In simulations and in in-vivo experiments half-Fourier imaging with the proposed L1-norm phase constraint enables superior performance both reconstruction of image details and with regard to robustness against phase estimation errors. The performance and feasibility of half-Fourier imaging with the proposed L1-norm phase constraint is reported. Its seamless combination with parallel imaging and compressed sensing enables use of greater acceleration in 3D MR imaging.

  11. Regularized Filters for L1-Norm-Based Common Spatial Patterns.

    PubMed

    Wang, Haixian; Li, Xiaomeng

    2016-02-01

    The l1 -norm-based common spatial patterns (CSP-L1) approach is a recently developed technique for optimizing spatial filters in the field of electroencephalogram (EEG)-based brain computer interfaces. The l1 -norm-based expression of dispersion in CSP-L1 alleviates the negative impact of outliers. In this paper, we further improve the robustness of CSP-L1 by taking into account noise which does not necessarily have as large a deviation as with outliers. The noise modelling is formulated by using the waveform length of the EEG time course. With the noise modelling, we then regularize the objective function of CSP-L1, in which the l1-norm is used in two folds: one is the dispersion and the other is the waveform length. An iterative algorithm is designed to resolve the optimization problem of the regularized objective function. A toy illustration and the experiments of classification on real EEG data sets show the effectiveness of the proposed method.

  12. Characterizing L1-norm best-fit subspaces

    NASA Astrophysics Data System (ADS)

    Brooks, J. Paul; Dulá, José H.

    2017-05-01

    Fitting affine objects to data is the basis of many tools and methodologies in statistics, machine learning, and signal processing. The L1 norm is often employed to produce subspaces exhibiting a robustness to outliers and faulty observations. The L1-norm best-fit subspace problem is directly formulated as a nonlinear, nonconvex, and nondifferentiable optimization problem. The case when the subspace is a hyperplane can be solved to global optimality efficiently by solving a series of linear programs. The problem of finding the best-fit line has recently been shown to be NP-hard. We present necessary conditions for optimality for the best-fit subspace problem, and use them to characterize properties of optimal solutions.

  13. Discriminant locality preserving projections based on L1-norm maximization.

    PubMed

    Zhong, Fujin; Zhang, Jiashu; Li, Defang

    2014-11-01

    Conventional discriminant locality preserving projection (DLPP) is a dimensionality reduction technique based on manifold learning, which has demonstrated good performance in pattern recognition. However, because its objective function is based on the distance criterion using L2-norm, conventional DLPP is not robust to outliers which are present in many applications. This paper proposes an effective and robust DLPP version based on L1-norm maximization, which learns a set of local optimal projection vectors by maximizing the ratio of the L1-norm-based locality preserving between-class dispersion and the L1-norm-based locality preserving within-class dispersion. The proposed method is proven to be feasible and also robust to outliers while overcoming the small sample size problem. The experimental results on artificial datasets, Binary Alphadigits dataset, FERET face dataset and PolyU palmprint dataset have demonstrated the effectiveness of the proposed method.

  14. Geometric artifacts reduction for cone-beam CT via L0-norm minimization without dedicated phantoms.

    PubMed

    Gong, Changcheng; Cai, Yufang; Zeng, Li

    2018-01-01

    For cone-beam computed tomography (CBCT), transversal shifts of the rotation center exist inevitably, which will result in geometric artifacts in CT images. In this work, we propose a novel geometric calibration method for CBCT, which can also be used in micro-CT. The symmetry property of the sinogram is used for the first calibration, and then L0-norm of the gradient image from the reconstructed image is used as the cost function to be minimized for the second calibration. An iterative search method is adopted to pursue the local minimum of the L0-norm minimization problem. The transversal shift value is updated with affirmatory step size within a search range determined by the first calibration. In addition, graphic processing unit (GPU)-based FDK algorithm and acceleration techniques are designed to accelerate the calibration process of the presented new method. In simulation experiments, the mean absolute difference (MAD) and the standard deviation (SD) of the transversal shift value were less than 0.2 pixels between the noise-free and noisy projection images, which indicated highly accurate calibration applying the new calibration method. In real data experiments, the smaller entropies of the corrected images also indicated that higher resolution image was acquired using the corrected projection data and the textures were well protected. Study results also support the feasibility of applying the proposed method to other imaging modalities.

  15. On epicardial potential reconstruction using regularization schemes with the L1-norm data term.

    PubMed

    Shou, Guofa; Xia, Ling; Liu, Feng; Jiang, Mingfeng; Crozier, Stuart

    2011-01-07

    The electrocardiographic (ECG) inverse problem is ill-posed and usually solved by regularization schemes. These regularization methods, such as the Tikhonov method, are often based on the L2-norm data and constraint terms. However, L2-norm-based methods inherently provide smoothed inverse solutions that are sensitive to measurement errors, and also lack the capability of localizing and distinguishing multiple proximal cardiac electrical sources. This paper presents alternative regularization schemes employing the L1-norm data term for the reconstruction of epicardial potentials (EPs) from measured body surface potentials (BSPs). During numerical implementation, the iteratively reweighted norm algorithm was applied to solve the L1-norm-related schemes, and measurement noises were considered in the BSP data. The proposed L1-norm data term-based regularization schemes (with L1 and L2 penalty terms of the normal derivative constraint (labelled as L1TV and L1L2)) were compared with the L2-norm data terms (Tikhonov with zero-order and normal derivative constraints, labelled as ZOT and FOT, and the total variation method labelled as L2TV). The studies demonstrated that, with averaged measurement noise, the inverse solutions provided by the L1L2 and FOT algorithms have less relative error values. However, when larger noise occurred in some electrodes (for example, signal lost during measurement), the L1TV and L1L2 methods can obtain more accurate EPs in a robust manner. Therefore the L1-norm data term-based solutions are generally less perturbed by measurement noises, suggesting that the new regularization scheme is promising for providing practical ECG inverse solutions.

  16. Correlation between the norm and the geometry of minimal networks

    NASA Astrophysics Data System (ADS)

    Laut, I. L.

    2017-05-01

    The paper is concerned with the inverse problem of the minimal Steiner network problem in a normed linear space. Namely, given a normed space in which all minimal networks are known for any finite point set, the problem is to describe all the norms on this space for which the minimal networks are the same as for the original norm. We survey the available results and prove that in the plane a rotund differentiable norm determines a distinctive set of minimal Steiner networks. In a two-dimensional space with rotund differentiable norm the coordinates of interior vertices of a nondegenerate minimal parametric network are shown to vary continuously under small deformations of the boundary set, and the turn direction of the network is determined. Bibliography: 15 titles.

  17. Automated ambiguity estimation for VLBI Intensive sessions using L1-norm

    NASA Astrophysics Data System (ADS)

    Kareinen, Niko; Hobiger, Thomas; Haas, Rüdiger

    2016-12-01

    Very Long Baseline Interferometry (VLBI) is a space-geodetic technique that is uniquely capable of direct observation of the angle of the Earth's rotation about the Celestial Intermediate Pole (CIP) axis, namely UT1. The daily estimates of the difference between UT1 and Coordinated Universal Time (UTC) provided by the 1-h long VLBI Intensive sessions are essential in providing timely UT1 estimates for satellite navigation systems and orbit determination. In order to produce timely UT1 estimates, efforts have been made to completely automate the analysis of VLBI Intensive sessions. This involves the automatic processing of X- and S-band group delays. These data contain an unknown number of integer ambiguities in the observed group delays. They are introduced as a side-effect of the bandwidth synthesis technique, which is used to combine correlator results from the narrow channels that span the individual bands. In an automated analysis with the c5++ software the standard approach in resolving the ambiguities is to perform a simplified parameter estimation using a least-squares adjustment (L2-norm minimisation). We implement L1-norm as an alternative estimation method in c5++. The implemented method is used to automatically estimate the ambiguities in VLBI Intensive sessions on the Kokee-Wettzell baseline. The results are compared to an analysis set-up where the ambiguity estimation is computed using the L2-norm. For both methods three different weighting strategies for the ambiguity estimation are assessed. The results show that the L1-norm is better at automatically resolving the ambiguities than the L2-norm. The use of the L1-norm leads to a significantly higher number of good quality UT1-UTC estimates with each of the three weighting strategies. The increase in the number of sessions is approximately 5% for each weighting strategy. This is accompanied by smaller post-fit residuals in the final UT1-UTC estimation step.

  18. Reconstruction algorithms based on l1-norm and l2-norm for two imaging models of fluorescence molecular tomography: a comparative study.

    PubMed

    Yi, Huangjian; Chen, Duofang; Li, Wei; Zhu, Shouping; Wang, Xiaorui; Liang, Jimin; Tian, Jie

    2013-05-01

    Fluorescence molecular tomography (FMT) is an important imaging technique of optical imaging. The major challenge of the reconstruction method for FMT is the ill-posed and underdetermined nature of the inverse problem. In past years, various regularization methods have been employed for fluorescence target reconstruction. A comparative study between the reconstruction algorithms based on l1-norm and l2-norm for two imaging models of FMT is presented. The first imaging model is adopted by most researchers, where the fluorescent target is of small size to mimic small tissue with fluorescent substance, as demonstrated by the early detection of a tumor. The second model is the reconstruction of distribution of the fluorescent substance in organs, which is essential to drug pharmacokinetics. Apart from numerical experiments, in vivo experiments were conducted on a dual-modality FMT/micro-computed tomography imaging system. The experimental results indicated that l1-norm regularization is more suitable for reconstructing the small fluorescent target, while l2-norm regularization performs better for the reconstruction of the distribution of fluorescent substance.

  19. Robust 2DPCA with non-greedy l1 -norm maximization for image analysis.

    PubMed

    Wang, Rong; Nie, Feiping; Yang, Xiaojun; Gao, Feifei; Yao, Minli

    2015-05-01

    2-D principal component analysis based on l1 -norm (2DPCA-L1) is a recently developed approach for robust dimensionality reduction and feature extraction in image domain. Normally, a greedy strategy is applied due to the difficulty of directly solving the l1 -norm maximization problem, which is, however, easy to get stuck in local solution. In this paper, we propose a robust 2DPCA with non-greedy l1 -norm maximization in which all projection directions are optimized simultaneously. Experimental results on face and other datasets confirm the effectiveness of the proposed approach.

  20. Nonconvex Nonsmooth Low Rank Minimization via Iteratively Reweighted Nuclear Norm.

    PubMed

    Lu, Canyi; Tang, Jinhui; Yan, Shuicheng; Lin, Zhouchen

    2016-02-01

    The nuclear norm is widely used as a convex surrogate of the rank function in compressive sensing for low rank matrix recovery with its applications in image recovery and signal processing. However, solving the nuclear norm-based relaxed convex problem usually leads to a suboptimal solution of the original rank minimization problem. In this paper, we propose to use a family of nonconvex surrogates of L0-norm on the singular values of a matrix to approximate the rank function. This leads to a nonconvex nonsmooth minimization problem. Then, we propose to solve the problem by an iteratively re-weighted nuclear norm (IRNN) algorithm. IRNN iteratively solves a weighted singular value thresholding problem, which has a closed form solution due to the special properties of the nonconvex surrogate functions. We also extend IRNN to solve the nonconvex problem with two or more blocks of variables. In theory, we prove that the IRNN decreases the objective function value monotonically, and any limit point is a stationary point. Extensive experiments on both synthesized data and real images demonstrate that IRNN enhances the low rank matrix recovery compared with the state-of-the-art convex algorithms.

  1. L1-norm locally linear representation regularization multi-source adaptation learning.

    PubMed

    Tao, Jianwen; Wen, Shiting; Hu, Wenjun

    2015-09-01

    In most supervised domain adaptation learning (DAL) tasks, one has access only to a small number of labeled examples from target domain. Therefore the success of supervised DAL in this "small sample" regime needs the effective utilization of the large amounts of unlabeled data to extract information that is useful for generalization. Toward this end, we here use the geometric intuition of manifold assumption to extend the established frameworks in existing model-based DAL methods for function learning by incorporating additional information about the target geometric structure of the marginal distribution. We would like to ensure that the solution is smooth with respect to both the ambient space and the target marginal distribution. In doing this, we propose a novel L1-norm locally linear representation regularization multi-source adaptation learning framework which exploits the geometry of the probability distribution, which has two techniques. Firstly, an L1-norm locally linear representation method is presented for robust graph construction by replacing the L2-norm reconstruction measure in LLE with L1-norm one, which is termed as L1-LLR for short. Secondly, considering the robust graph regularization, we replace traditional graph Laplacian regularization with our new L1-LLR graph Laplacian regularization and therefore construct new graph-based semi-supervised learning framework with multi-source adaptation constraint, which is coined as L1-MSAL method. Moreover, to deal with the nonlinear learning problem, we also generalize the L1-MSAL method by mapping the input data points from the input space to a high-dimensional reproducing kernel Hilbert space (RKHS) via a nonlinear mapping. Promising experimental results have been obtained on several real-world datasets such as face, visual video and object. Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. Spectral L2/L1 norm: A new perspective for spectral kurtosis for characterizing non-stationary signals

    NASA Astrophysics Data System (ADS)

    Wang, Dong

    2018-05-01

    Thanks to the great efforts made by Antoni (2006), spectral kurtosis has been recognized as a milestone for characterizing non-stationary signals, especially bearing fault signals. The main idea of spectral kurtosis is to use the fourth standardized moment, namely kurtosis, as a function of spectral frequency so as to indicate how repetitive transients caused by a bearing defect vary with frequency. Moreover, spectral kurtosis is defined based on an analytic bearing fault signal constructed from either a complex filter or Hilbert transform. On the other hand, another attractive work was reported by Borghesani et al. (2014) to mathematically reveal the relationship between the kurtosis of an analytical bearing fault signal and the square of the squared envelope spectrum of the analytical bearing fault signal for explaining spectral correlation for quantification of bearing fault signals. More interestingly, it was discovered that the sum of peaks at cyclic frequencies in the square of the squared envelope spectrum corresponds to the raw 4th order moment. Inspired by the aforementioned works, in this paper, we mathematically show that: (1) spectral kurtosis can be decomposed into squared envelope and squared L2/L1 norm so that spectral kurtosis can be explained as spectral squared L2/L1 norm; (2) spectral L2/L1 norm is formally defined for characterizing bearing fault signals and its two geometrical explanations are made; (3) spectral L2/L1 norm is proportional to the square root of the sum of peaks at cyclic frequencies in the square of the squared envelope spectrum; (4) some extensions of spectral L2/L1 norm for characterizing bearing fault signals are pointed out.

  3. Bilinear Factor Matrix Norm Minimization for Robust PCA: Algorithms and Applications.

    PubMed

    Shang, Fanhua; Cheng, James; Liu, Yuanyuan; Luo, Zhi-Quan; Lin, Zhouchen

    2017-09-04

    The heavy-tailed distributions of corrupted outliers and singular values of all channels in low-level vision have proven effective priors for many applications such as background modeling, photometric stereo and image alignment. And they can be well modeled by a hyper-Laplacian. However, the use of such distributions generally leads to challenging non-convex, non-smooth and non-Lipschitz problems, and makes existing algorithms very slow for large-scale applications. Together with the analytic solutions to Lp-norm minimization with two specific values of p, i.e., p=1/2 and p=2/3, we propose two novel bilinear factor matrix norm minimization models for robust principal component analysis. We first define the double nuclear norm and Frobenius/nuclear hybrid norm penalties, and then prove that they are in essence the Schatten-1/2 and 2/3 quasi-norms, respectively, which lead to much more tractable and scalable Lipschitz optimization problems. Our experimental analysis shows that both our methods yield more accurate solutions than original Schatten quasi-norm minimization, even when the number of observations is very limited. Finally, we apply our penalties to various low-level vision problems, e.g. moving object detection, image alignment and inpainting, and show that our methods usually outperform the state-of-the-art methods.

  4. Application of L1-norm regularization to epicardial potential reconstruction based on gradient projection.

    PubMed

    Wang, Liansheng; Qin, Jing; Wong, Tien Tsin; Heng, Pheng Ann

    2011-10-07

    The epicardial potential (EP)-targeted inverse problem of electrocardiography (ECG) has been widely investigated as it is demonstrated that EPs reflect underlying myocardial activity. It is a well-known ill-posed problem as small noises in input data may yield a highly unstable solution. Traditionally, L2-norm regularization methods have been proposed to solve this ill-posed problem. But the L2-norm penalty function inherently leads to considerable smoothing of the solution, which reduces the accuracy of distinguishing abnormalities and locating diseased regions. Directly using the L1-norm penalty function, however, may greatly increase computational complexity due to its non-differentiability. We propose an L1-norm regularization method in order to reduce the computational complexity and make rapid convergence possible. Variable splitting is employed to make the L1-norm penalty function differentiable based on the observation that both positive and negative potentials exist on the epicardial surface. Then, the inverse problem of ECG is further formulated as a bound-constrained quadratic problem, which can be efficiently solved by gradient projection in an iterative manner. Extensive experiments conducted on both synthetic data and real data demonstrate that the proposed method can handle both measurement noise and geometry noise and obtain more accurate results than previous L2- and L1-norm regularization methods, especially when the noises are large.

  5. WE-G-207-04: Non-Local Total-Variation (NLTV) Combined with Reweighted L1-Norm for Compressed Sensing Based CT Reconstruction

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, H; Chen, J; Pouliot, J

    2015-06-15

    Purpose: Compressed sensing (CS) has been used for CT (4DCT/CBCT) reconstruction with few projections to reduce dose of radiation. Total-variation (TV) in L1-minimization (min.) with local information is the prevalent technique in CS, while it can be prone to noise. To address the problem, this work proposes to apply a new image processing technique, called non-local TV (NLTV), to CS based CT reconstruction, and incorporate reweighted L1-norm into it for more precise reconstruction. Methods: TV minimizes intensity variations by considering two local neighboring voxels, which can be prone to noise, possibly damaging the reconstructed CT image. NLTV, contrarily, utilizes moremore » global information by computing a weight function of current voxel relative to surrounding search area. In fact, it might be challenging to obtain an optimal solution due to difficulty in defining the weight function with appropriate parameters. Introducing reweighted L1-min., designed for approximation to ideal L0-min., can reduce the dependence on defining the weight function, therefore improving accuracy of the solution. This work implemented the NLTV combined with reweighted L1-min. by Split Bregman Iterative method. For evaluation, a noisy digital phantom and a pelvic CT images are employed to compare the quality of images reconstructed by TV, NLTV and reweighted NLTV. Results: In both cases, conventional and reweighted NLTV outperform TV min. in signal-to-noise ratio (SNR) and root-mean squared errors of the reconstructed images. Relative to conventional NLTV, NLTV with reweighted L1-norm was able to slightly improve SNR, while greatly increasing the contrast between tissues due to additional iterative reweighting process. Conclusion: NLTV min. can provide more precise compressed sensing based CT image reconstruction by incorporating the reweighted L1-norm, while maintaining greater robustness to the noise effect than TV min.« less

  6. L1-norm kernel discriminant analysis via Bayes error bound optimization for robust feature extraction.

    PubMed

    Zheng, Wenming; Lin, Zhouchen; Wang, Haixian

    2014-04-01

    A novel discriminant analysis criterion is derived in this paper under the theoretical framework of Bayes optimality. In contrast to the conventional Fisher's discriminant criterion, the major novelty of the proposed one is the use of L1 norm rather than L2 norm, which makes it less sensitive to the outliers. With the L1-norm discriminant criterion, we propose a new linear discriminant analysis (L1-LDA) method for linear feature extraction problem. To solve the L1-LDA optimization problem, we propose an efficient iterative algorithm, in which a novel surrogate convex function is introduced such that the optimization problem in each iteration is to simply solve a convex programming problem and a close-form solution is guaranteed to this problem. Moreover, we also generalize the L1-LDA method to deal with the nonlinear robust feature extraction problems via the use of kernel trick, and hereafter proposed the L1-norm kernel discriminant analysis (L1-KDA) method. Extensive experiments on simulated and real data sets are conducted to evaluate the effectiveness of the proposed method in comparing with the state-of-the-art methods.

  7. Suppressing multiples using an adaptive multichannel filter based on L1-norm

    NASA Astrophysics Data System (ADS)

    Shi, Ying; Jing, Hongliang; Zhang, Wenwu; Ning, Dezhi

    2017-08-01

    Adaptive subtraction is an important link for removing surface-related multiples in the wave equation-based method. In this paper, we propose an adaptive multichannel subtraction method based on the L1-norm. We achieve enhanced compensation for the mismatch between the input seismogram and the predicted multiples in terms of the amplitude, phase, frequency band, and travel time. Unlike the conventional L2-norm, the proposed method does not rely on the assumption that the primary and the multiples are orthogonal, and also takes advantage of the fact that the L1-norm is more robust when dealing with outliers. In addition, we propose a frequency band extension via modulation to reconstruct the high frequencies to compensate for the frequency misalignment. We present a parallel computing scheme to accelerate the subtraction algorithm on graphic processing units (GPUs), which significantly reduces the computational cost. The synthetic and field seismic data tests show that the proposed method effectively suppresses the multiples.

  8. L1 norm based common spatial patterns decomposition for scalp EEG BCI.

    PubMed

    Li, Peiyang; Xu, Peng; Zhang, Rui; Guo, Lanjin; Yao, Dezhong

    2013-08-06

    Brain computer interfaces (BCI) is one of the most popular branches in biomedical engineering. It aims at constructing a communication between the disabled persons and the auxiliary equipments in order to improve the patients' life. In motor imagery (MI) based BCI, one of the popular feature extraction strategies is Common Spatial Patterns (CSP). In practical BCI situation, scalp EEG inevitably has the outlier and artifacts introduced by ocular, head motion or the loose contact of electrodes in scalp EEG recordings. Because outlier and artifacts are usually observed with large amplitude, when CSP is solved in view of L2 norm, the effect of outlier and artifacts will be exaggerated due to the imposing of square to outliers, which will finally influence the MI based BCI performance. While L1 norm will lower the outlier effects as proved in other application fields like EEG inverse problem, face recognition, etc. In this paper, we present a new CSP implementation using the L1 norm technique, instead of the L2 norm, to solve the eigen problem for spatial filter estimation with aim to improve the robustness of CSP to outliers. To evaluate the performance of our method, we applied our method as well as the standard CSP and the regularized CSP with Tikhonov regularization (TR-CSP), on both the peer BCI dataset with simulated outliers and the dataset from the MI BCI system developed in our group. The McNemar test is used to investigate whether the difference among the three CSPs is of statistical significance. The results of both the simulation and real BCI datasets consistently reveal that the proposed method has much higher classification accuracies than the conventional CSP and the TR-CSP. By combining L1 norm based Eigen decomposition into Common Spatial Patterns, the proposed approach can effectively improve the robustness of BCI system to EEG outliers and thus be potential for the actual MI BCI application, where outliers are inevitably introduced into EEG recordings.

  9. The Exact Solution to Rank-1 L1-Norm TUCKER2 Decomposition

    NASA Astrophysics Data System (ADS)

    Markopoulos, Panos P.; Chachlakis, Dimitris G.; Papalexakis, Evangelos E.

    2018-04-01

    We study rank-1 {L1-norm-based TUCKER2} (L1-TUCKER2) decomposition of 3-way tensors, treated as a collection of $N$ $D \\times M$ matrices that are to be jointly decomposed. Our contributions are as follows. i) We prove that the problem is equivalent to combinatorial optimization over $N$ antipodal-binary variables. ii) We derive the first two algorithms in the literature for its exact solution. The first algorithm has cost exponential in $N$; the second one has cost polynomial in $N$ (under a mild assumption). Our algorithms are accompanied by formal complexity analysis. iii) We conduct numerical studies to compare the performance of exact L1-TUCKER2 (proposed) with standard HOSVD, HOOI, GLRAM, PCA, L1-PCA, and TPCA-L1. Our studies show that L1-TUCKER2 outperforms (in tensor approximation) all the above counterparts when the processed data are outlier corrupted.

  10. Improving IMRT delivery efficiency with reweighted L1-minimization for inverse planning

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, Hojin; Becker, Stephen; Lee, Rena

    2013-07-15

    Purpose: This study presents an improved technique to further simplify the fluence-map in intensity modulated radiation therapy (IMRT) inverse planning, thereby reducing plan complexity and improving delivery efficiency, while maintaining the plan quality.Methods: First-order total-variation (TV) minimization (min.) based on L1-norm has been proposed to reduce the complexity of fluence-map in IMRT by generating sparse fluence-map variations. However, with stronger dose sparing to the critical structures, the inevitable increase in the fluence-map complexity can lead to inefficient dose delivery. Theoretically, L0-min. is the ideal solution for the sparse signal recovery problem, yet practically intractable due to its nonconvexity of themore » objective function. As an alternative, the authors use the iteratively reweighted L1-min. technique to incorporate the benefits of the L0-norm into the tractability of L1-min. The weight multiplied to each element is inversely related to the magnitude of the corresponding element, which is iteratively updated by the reweighting process. The proposed penalizing process combined with TV min. further improves sparsity in the fluence-map variations, hence ultimately enhancing the delivery efficiency. To validate the proposed method, this work compares three treatment plans obtained from quadratic min. (generally used in clinic IMRT), conventional TV min., and our proposed reweighted TV min. techniques, implemented by a large-scale L1-solver (template for first-order conic solver), for five patient clinical data. Criteria such as conformation number (CN), modulation index (MI), and estimated treatment time are employed to assess the relationship between the plan quality and delivery efficiency.Results: The proposed method yields simpler fluence-maps than the quadratic and conventional TV based techniques. To attain a given CN and dose sparing to the critical organs for 5 clinical cases, the proposed method reduces the number of

  11. Minimal norm constrained interpolation. Ph.D. Thesis

    NASA Technical Reports Server (NTRS)

    Irvine, L. D.

    1985-01-01

    In computational fluid dynamics and in CAD/CAM, a physical boundary is usually known only discreetly and most often must be approximated. An acceptable approximation preserves the salient features of the data such as convexity and concavity. In this dissertation, a smooth interpolant which is locally concave where the data are concave and is locally convex where the data are convex is described. The interpolant is found by posing and solving a minimization problem whose solution is a piecewise cubic polynomial. The problem is solved indirectly by using the Peano Kernal theorem to recast it into an equivalent minimization problem having the second derivative of the interpolant as the solution. This approach leads to the solution of a nonlinear system of equations. It is shown that Newton's method is an exceptionally attractive and efficient method for solving the nonlinear system of equations. Examples of shape-preserving interpolants, as well as convergence results obtained by using Newton's method are also shown. A FORTRAN program to compute these interpolants is listed. The problem of computing the interpolant of minimal norm from a convex cone in a normal dual space is also discussed. An extension of de Boor's work on minimal norm unconstrained interpolation is presented.

  12. Improving Generalization Based on l1-Norm Regularization for EEG-Based Motor Imagery Classification

    PubMed Central

    Zhao, Yuwei; Han, Jiuqi; Chen, Yushu; Sun, Hongji; Chen, Jiayun; Ke, Ang; Han, Yao; Zhang, Peng; Zhang, Yi; Zhou, Jin; Wang, Changyong

    2018-01-01

    Multichannel electroencephalography (EEG) is widely used in typical brain-computer interface (BCI) systems. In general, a number of parameters are essential for a EEG classification algorithm due to redundant features involved in EEG signals. However, the generalization of the EEG method is often adversely affected by the model complexity, considerably coherent with its number of undetermined parameters, further leading to heavy overfitting. To decrease the complexity and improve the generalization of EEG method, we present a novel l1-norm-based approach to combine the decision value obtained from each EEG channel directly. By extracting the information from different channels on independent frequency bands (FB) with l1-norm regularization, the method proposed fits the training data with much less parameters compared to common spatial pattern (CSP) methods in order to reduce overfitting. Moreover, an effective and efficient solution to minimize the optimization object is proposed. The experimental results on dataset IVa of BCI competition III and dataset I of BCI competition IV show that, the proposed method contributes to high classification accuracy and increases generalization performance for the classification of MI EEG. As the training set ratio decreases from 80 to 20%, the average classification accuracy on the two datasets changes from 85.86 and 86.13% to 84.81 and 76.59%, respectively. The classification performance and generalization of the proposed method contribute to the practical application of MI based BCI systems. PMID:29867307

  13. Low-dose CT reconstruction via L1 dictionary learning regularization using iteratively reweighted least-squares.

    PubMed

    Zhang, Cheng; Zhang, Tao; Li, Ming; Peng, Chengtao; Liu, Zhaobang; Zheng, Jian

    2016-06-18

    In order to reduce the radiation dose of CT (computed tomography), compressed sensing theory has been a hot topic since it provides the possibility of a high quality recovery from the sparse sampling data. Recently, the algorithm based on DL (dictionary learning) was developed to deal with the sparse CT reconstruction problem. However, the existing DL algorithm focuses on the minimization problem with the L2-norm regularization term, which leads to reconstruction quality deteriorating while the sampling rate declines further. Therefore, it is essential to improve the DL method to meet the demand of more dose reduction. In this paper, we replaced the L2-norm regularization term with the L1-norm one. It is expected that the proposed L1-DL method could alleviate the over-smoothing effect of the L2-minimization and reserve more image details. The proposed algorithm solves the L1-minimization problem by a weighting strategy, solving the new weighted L2-minimization problem based on IRLS (iteratively reweighted least squares). Through the numerical simulation, the proposed algorithm is compared with the existing DL method (adaptive dictionary based statistical iterative reconstruction, ADSIR) and other two typical compressed sensing algorithms. It is revealed that the proposed algorithm is more accurate than the other algorithms especially when further reducing the sampling rate or increasing the noise. The proposed L1-DL algorithm can utilize more prior information of image sparsity than ADSIR. By transforming the L2-norm regularization term of ADSIR with the L1-norm one and solving the L1-minimization problem by IRLS strategy, L1-DL could reconstruct the image more exactly.

  14. Robust subspace clustering via joint weighted Schatten-p norm and Lq norm minimization

    NASA Astrophysics Data System (ADS)

    Zhang, Tao; Tang, Zhenmin; Liu, Qing

    2017-05-01

    Low-rank representation (LRR) has been successfully applied to subspace clustering. However, the nuclear norm in the standard LRR is not optimal for approximating the rank function in many real-world applications. Meanwhile, the L21 norm in LRR also fails to characterize various noises properly. To address the above issues, we propose an improved LRR method, which achieves low rank property via the new formulation with weighted Schatten-p norm and Lq norm (WSPQ). Specifically, the nuclear norm is generalized to be the Schatten-p norm and different weights are assigned to the singular values, and thus it can approximate the rank function more accurately. In addition, Lq norm is further incorporated into WSPQ to model different noises and improve the robustness. An efficient algorithm based on the inexact augmented Lagrange multiplier method is designed for the formulated problem. Extensive experiments on face clustering and motion segmentation clearly demonstrate the superiority of the proposed WSPQ over several state-of-the-art methods.

  15. Time Series Imputation via L1 Norm-Based Singular Spectrum Analysis

    NASA Astrophysics Data System (ADS)

    Kalantari, Mahdi; Yarmohammadi, Masoud; Hassani, Hossein; Silva, Emmanuel Sirimal

    Missing values in time series data is a well-known and important problem which many researchers have studied extensively in various fields. In this paper, a new nonparametric approach for missing value imputation in time series is proposed. The main novelty of this research is applying the L1 norm-based version of Singular Spectrum Analysis (SSA), namely L1-SSA which is robust against outliers. The performance of the new imputation method has been compared with many other established methods. The comparison is done by applying them to various real and simulated time series. The obtained results confirm that the SSA-based methods, especially L1-SSA can provide better imputation in comparison to other methods.

  16. Multivariable frequency domain identification via 2-norm minimization

    NASA Technical Reports Server (NTRS)

    Bayard, David S.

    1992-01-01

    The author develops a computational approach to multivariable frequency domain identification, based on 2-norm minimization. In particular, a Gauss-Newton (GN) iteration is developed to minimize the 2-norm of the error between frequency domain data and a matrix fraction transfer function estimate. To improve the global performance of the optimization algorithm, the GN iteration is initialized using the solution to a particular sequentially reweighted least squares problem, denoted as the SK iteration. The least squares problems which arise from both the SK and GN iterations are shown to involve sparse matrices with identical block structure. A sparse matrix QR factorization method is developed to exploit the special block structure, and to efficiently compute the least squares solution. A numerical example involving the identification of a multiple-input multiple-output (MIMO) plant having 286 unknown parameters is given to illustrate the effectiveness of the algorithm.

  17. Arbitrary norm support vector machines.

    PubMed

    Huang, Kaizhu; Zheng, Danian; King, Irwin; Lyu, Michael R

    2009-02-01

    Support vector machines (SVM) are state-of-the-art classifiers. Typically L2-norm or L1-norm is adopted as a regularization term in SVMs, while other norm-based SVMs, for example, the L0-norm SVM or even the L(infinity)-norm SVM, are rarely seen in the literature. The major reason is that L0-norm describes a discontinuous and nonconvex term, leading to a combinatorially NP-hard optimization problem. In this letter, motivated by Bayesian learning, we propose a novel framework that can implement arbitrary norm-based SVMs in polynomial time. One significant feature of this framework is that only a sequence of sequential minimal optimization problems needs to be solved, thus making it practical in many real applications. The proposed framework is important in the sense that Bayesian priors can be efficiently plugged into most learning methods without knowing the explicit form. Hence, this builds a connection between Bayesian learning and the kernel machines. We derive the theoretical framework, demonstrate how our approach works on the L0-norm SVM as a typical example, and perform a series of experiments to validate its advantages. Experimental results on nine benchmark data sets are very encouraging. The implemented L0-norm is competitive with or even better than the standard L2-norm SVM in terms of accuracy but with a reduced number of support vectors, -9.46% of the number on average. When compared with another sparse model, the relevance vector machine, our proposed algorithm also demonstrates better sparse properties with a training speed over seven times faster.

  18. Efficient l1 -norm-based low-rank matrix approximations for large-scale problems using alternating rectified gradient method.

    PubMed

    Kim, Eunwoo; Lee, Minsik; Choi, Chong-Ho; Kwak, Nojun; Oh, Songhwai

    2015-02-01

    Low-rank matrix approximation plays an important role in the area of computer vision and image processing. Most of the conventional low-rank matrix approximation methods are based on the l2 -norm (Frobenius norm) with principal component analysis (PCA) being the most popular among them. However, this can give a poor approximation for data contaminated by outliers (including missing data), because the l2 -norm exaggerates the negative effect of outliers. Recently, to overcome this problem, various methods based on the l1 -norm, such as robust PCA methods, have been proposed for low-rank matrix approximation. Despite the robustness of the methods, they require heavy computational effort and substantial memory for high-dimensional data, which is impractical for real-world problems. In this paper, we propose two efficient low-rank factorization methods based on the l1 -norm that find proper projection and coefficient matrices using the alternating rectified gradient method. The proposed methods are applied to a number of low-rank matrix approximation problems to demonstrate their efficiency and robustness. The experimental results show that our proposals are efficient in both execution time and reconstruction performance unlike other state-of-the-art methods.

  19. Improved pressure-velocity coupling algorithm based on minimization of global residual norm

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chatwani, A.U.; Turan, A.

    1991-01-01

    In this paper an improved pressure velocity coupling algorithm is proposed based on the minimization of the global residual norm. The procedure is applied to SIMPLE and SIMPLEC algorithms to automatically select the pressure underrelaxation factor to minimize the global residual norm at each iteration level. Test computations for three-dimensional turbulent, isothermal flow is a toroidal vortex combustor indicate that velocity underrelaxation factors as high as 0.7 can be used to obtain a converged solution in 300 iterations.

  20. Simple modification of Oja rule limits L1-norm of weight vector and leads to sparse connectivity.

    PubMed

    Aparin, Vladimir

    2012-03-01

    This letter describes a simple modification of the Oja learning rule, which asymptotically constrains the L1-norm of an input weight vector instead of the L2-norm as in the original rule. This constraining is local as opposed to commonly used instant normalizations, which require the knowledge of all input weights of a neuron to update each one of them individually. The proposed rule converges to a weight vector that is sparser (has more zero weights) than the vector learned by the original Oja rule with or without the zero bound, which could explain the developmental synaptic pruning.

  1. Image restoration by minimizing zero norm of wavelet frame coefficients

    NASA Astrophysics Data System (ADS)

    Bao, Chenglong; Dong, Bin; Hou, Likun; Shen, Zuowei; Zhang, Xiaoqun; Zhang, Xue

    2016-11-01

    In this paper, we propose two algorithms, namely the extrapolated proximal iterative hard thresholding (EPIHT) algorithm and the EPIHT algorithm with line-search, for solving the {{\\ell }}0-norm regularized wavelet frame balanced approach for image restoration. Under the theoretical framework of Kurdyka-Łojasiewicz property, we show that the sequences generated by the two algorithms converge to a local minimizer with linear convergence rate. Moreover, extensive numerical experiments on sparse signal reconstruction and wavelet frame based image restoration problems including CT reconstruction, image deblur, demonstrate the improvement of {{\\ell }}0-norm based regularization models over some prevailing ones, as well as the computational efficiency of the proposed algorithms.

  2. Image registration using stationary velocity fields parameterized by norm-minimizing Wendland kernel

    NASA Astrophysics Data System (ADS)

    Pai, Akshay; Sommer, Stefan; Sørensen, Lauge; Darkner, Sune; Sporring, Jon; Nielsen, Mads

    2015-03-01

    Interpolating kernels are crucial to solving a stationary velocity field (SVF) based image registration problem. This is because, velocity fields need to be computed in non-integer locations during integration. The regularity in the solution to the SVF registration problem is controlled by the regularization term. In a variational formulation, this term is traditionally expressed as a squared norm which is a scalar inner product of the interpolating kernels parameterizing the velocity fields. The minimization of this term using the standard spline interpolation kernels (linear or cubic) is only approximative because of the lack of a compatible norm. In this paper, we propose to replace such interpolants with a norm-minimizing interpolant - the Wendland kernel which has the same computational simplicity like B-Splines. An application on the Alzheimer's disease neuroimaging initiative showed that Wendland SVF based measures separate (Alzheimer's disease v/s normal controls) better than both B-Spline SVFs (p<0.05 in amygdala) and B-Spline freeform deformation (p<0.05 in amygdala and cortical gray matter).

  3. Concave 1-norm group selection

    PubMed Central

    Jiang, Dingfeng; Huang, Jian

    2015-01-01

    Grouping structures arise naturally in many high-dimensional problems. Incorporation of such information can improve model fitting and variable selection. Existing group selection methods, such as the group Lasso, require correct membership. However, in practice it can be difficult to correctly specify group membership of all variables. Thus, it is important to develop group selection methods that are robust against group mis-specification. Also, it is desirable to select groups as well as individual variables in many applications. We propose a class of concave \\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{upgreek} \\usepackage{mathrsfs} \\setlength{\\oddsidemargin}{-69pt} \\begin{document} }{}$1$\\end{document}-norm group penalties that is robust to grouping structure and can perform bi-level selection. A coordinate descent algorithm is developed to calculate solutions of the proposed group selection method. Theoretical convergence of the algorithm is proved under certain regularity conditions. Comparison with other methods suggests the proposed method is the most robust approach under membership mis-specification. Simulation studies and real data application indicate that the \\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{upgreek} \\usepackage{mathrsfs} \\setlength{\\oddsidemargin}{-69pt} \\begin{document} }{}$1$\\end{document}-norm concave group selection approach achieves better control of false discovery rates. An R package grppenalty implementing the proposed method is available at CRAN. PMID:25417206

  4. Nonlinear gamma correction via normed bicoherence minimization in optical fringe projection metrology

    NASA Astrophysics Data System (ADS)

    Kamagara, Abel; Wang, Xiangzhao; Li, Sikun

    2018-03-01

    We propose a method to compensate for the projector intensity nonlinearity induced by gamma effect in three-dimensional (3-D) fringe projection metrology by extending high-order spectra analysis and bispectral norm minimization to digital sinusoidal fringe pattern analysis. The bispectrum estimate allows extraction of vital signal information features such as spectral component correlation relationships in fringe pattern images. Our approach exploits the fact that gamma introduces high-order harmonic correlations in the affected fringe pattern image. Estimation and compensation of projector nonlinearity is realized by detecting and minimizing the normed bispectral coherence of these correlations. The proposed technique does not require calibration information and technical knowledge or specification of fringe projection unit. This is promising for developing a modular and calibration-invariant model for intensity nonlinear gamma compensation in digital fringe pattern projection profilometry. Experimental and numerical simulation results demonstrate this method to be efficient and effective in improving the phase measuring accuracies with phase-shifting fringe pattern projection profilometry.

  5. Passive shimming of a superconducting magnet using the L1-norm regularized least square algorithm.

    PubMed

    Kong, Xia; Zhu, Minhua; Xia, Ling; Wang, Qiuliang; Li, Yi; Zhu, Xuchen; Liu, Feng; Crozier, Stuart

    2016-02-01

    The uniformity of the static magnetic field B0 is of prime importance for an MRI system. The passive shimming technique is usually applied to improve the uniformity of the static field by optimizing the layout of a series of steel shims. The steel pieces are fixed in the drawers in the inner bore of the superconducting magnet, and produce a magnetizing field in the imaging region to compensate for the inhomogeneity of the B0 field. In practice, the total mass of steel used for shimming should be minimized, in addition to the field uniformity requirement. This is because the presence of steel shims may introduce a thermal stability problem. The passive shimming procedure is typically realized using the linear programming (LP) method. The LP approach however, is generally slow and also has difficulty balancing the field quality and the total amount of steel for shimming. In this paper, we have developed a new algorithm that is better able to balance the dual constraints of field uniformity and the total mass of the shims. The least square method is used to minimize the magnetic field inhomogeneity over the imaging surface with the total mass of steel being controlled by an L1-norm based constraint. The proposed algorithm has been tested with practical field data, and the results show that, with similar computational cost and mass of shim material, the new algorithm achieves superior field uniformity (43% better for the test case) compared with the conventional linear programming approach. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Smoothed low rank and sparse matrix recovery by iteratively reweighted least squares minimization.

    PubMed

    Lu, Canyi; Lin, Zhouchen; Yan, Shuicheng

    2015-02-01

    This paper presents a general framework for solving the low-rank and/or sparse matrix minimization problems, which may involve multiple nonsmooth terms. The iteratively reweighted least squares (IRLSs) method is a fast solver, which smooths the objective function and minimizes it by alternately updating the variables and their weights. However, the traditional IRLS can only solve a sparse only or low rank only minimization problem with squared loss or an affine constraint. This paper generalizes IRLS to solve joint/mixed low-rank and sparse minimization problems, which are essential formulations for many tasks. As a concrete example, we solve the Schatten-p norm and l2,q-norm regularized low-rank representation problem by IRLS, and theoretically prove that the derived solution is a stationary point (globally optimal if p,q ≥ 1). Our convergence proof of IRLS is more general than previous one that depends on the special properties of the Schatten-p norm and l2,q-norm. Extensive experiments on both synthetic and real data sets demonstrate that our IRLS is much more efficient.

  7. Direction of Arrival Estimation for MIMO Radar via Unitary Nuclear Norm Minimization

    PubMed Central

    Wang, Xianpeng; Huang, Mengxing; Wu, Xiaoqin; Bi, Guoan

    2017-01-01

    In this paper, we consider the direction of arrival (DOA) estimation issue of noncircular (NC) source in multiple-input multiple-output (MIMO) radar and propose a novel unitary nuclear norm minimization (UNNM) algorithm. In the proposed method, the noncircular properties of signals are used to double the virtual array aperture, and the real-valued data are obtained by utilizing unitary transformation. Then a real-valued block sparse model is established based on a novel over-complete dictionary, and a UNNM algorithm is formulated for recovering the block-sparse matrix. In addition, the real-valued NC-MUSIC spectrum is used to design a weight matrix for reweighting the nuclear norm minimization to achieve the enhanced sparsity of solutions. Finally, the DOA is estimated by searching the non-zero blocks of the recovered matrix. Because of using the noncircular properties of signals to extend the virtual array aperture and an additional real structure to suppress the noise, the proposed method provides better performance compared with the conventional sparse recovery based algorithms. Furthermore, the proposed method can handle the case of underdetermined DOA estimation. Simulation results show the effectiveness and advantages of the proposed method. PMID:28441770

  8. Moving force identification based on redundant concatenated dictionary and weighted l1-norm regularization

    NASA Astrophysics Data System (ADS)

    Pan, Chu-Dong; Yu, Ling; Liu, Huan-Lin; Chen, Ze-Peng; Luo, Wen-Feng

    2018-01-01

    Moving force identification (MFI) is an important inverse problem in the field of bridge structural health monitoring (SHM). Reasonable signal structures of moving forces are rarely considered in the existing MFI methods. Interaction forces are complex because they contain both slowly-varying harmonic and impact signals due to bridge vibration and bumps on a bridge deck, respectively. Therefore, the interaction forces are usually hard to be expressed completely and sparsely by using a single basis function set. Based on the redundant concatenated dictionary and weighted l1-norm regularization method, a hybrid method is proposed for MFI in this study. The redundant dictionary consists of both trigonometric functions and rectangular functions used for matching the harmonic and impact signal features of unknown moving forces. The weighted l1-norm regularization method is introduced for formulation of MFI equation, so that the signal features of moving forces can be accurately extracted. The fast iterative shrinkage-thresholding algorithm (FISTA) is used for solving the MFI problem. The optimal regularization parameter is appropriately chosen by the Bayesian information criterion (BIC) method. In order to assess the accuracy and the feasibility of the proposed method, a simply-supported beam bridge subjected to a moving force is taken as an example for numerical simulations. Finally, a series of experimental studies on MFI of a steel beam are performed in laboratory. Both numerical and experimental results show that the proposed method can accurately identify the moving forces with a strong robustness, and it has a better performance than the Tikhonov regularization method. Some related issues are discussed as well.

  9. Multi-normed spaces based on non-discrete measures and their tensor products

    NASA Astrophysics Data System (ADS)

    Helemskii, A. Ya.

    2018-04-01

    Lambert discovered a new type of structures situated, in a sense, between normed spaces and abstract operator spaces. His definition was based on the notion of amplifying a normed space by means of the spaces \\ell_2^n. Later, several mathematicians studied more general structures (`p-multi- normed spaces') introduced by means of the spaces \\ell_p^n, 1≤ p≤∞. We pass from \\ell_p to L_p(X,μ) with an arbitrary measure. This becomes possible in the framework of the non- coordinate approach to the notion of amplification. In the case of a discrete counting measure, this approach is equivalent to the approach in the papers mentioned. Two categories arise. One consists of amplifications by means of an arbitrary normed space, and the other consists of p-convex amplifications by means of L_p(X,μ). Each of them has its own tensor product of objects (the existence of each product is proved by a separate explicit construction). As a final result, we show that the `p-convex' tensor product has an especially transparent form for the minimal L_p-amplifications of L_q-spaces, where q is conjugate to p. Namely, tensoring L_q(Y,ν) and L_q(Z,λ), we obtain L_q(Y× Z, ν×λ).

  10. Joint Smoothed l₀-Norm DOA Estimation Algorithm for Multiple Measurement Vectors in MIMO Radar.

    PubMed

    Liu, Jing; Zhou, Weidong; Juwono, Filbert H

    2017-05-08

    Direction-of-arrival (DOA) estimation is usually confronted with a multiple measurement vector (MMV) case. In this paper, a novel fast sparse DOA estimation algorithm, named the joint smoothed l 0 -norm algorithm, is proposed for multiple measurement vectors in multiple-input multiple-output (MIMO) radar. To eliminate the white or colored Gaussian noises, the new method first obtains a low-complexity high-order cumulants based data matrix. Then, the proposed algorithm designs a joint smoothed function tailored for the MMV case, based on which joint smoothed l 0 -norm sparse representation framework is constructed. Finally, for the MMV-based joint smoothed function, the corresponding gradient-based sparse signal reconstruction is designed, thus the DOA estimation can be achieved. The proposed method is a fast sparse representation algorithm, which can solve the MMV problem and perform well for both white and colored Gaussian noises. The proposed joint algorithm is about two orders of magnitude faster than the l 1 -norm minimization based methods, such as l 1 -SVD (singular value decomposition), RV (real-valued) l 1 -SVD and RV l 1 -SRACV (sparse representation array covariance vectors), and achieves better DOA estimation performance.

  11. Quantum System Identification via L1-norm Minimization

    DTIC Science & Technology

    2011-06-30

    number of entangled states for varying levels of amplitude damping γ. tude damping γ. In photonic systems γ is the probability of a photon loss. In...quantum process is a photonic entangling gate. A measurement configuration is defined as some combination of state preparation and an observable...first experimental demonstration of QPT via CS on a photonic system at the University of Queensland. The latter experimental results showed the

  12. Reduction of speckle noise from optical coherence tomography images using multi-frame weighted nuclear norm minimization method

    NASA Astrophysics Data System (ADS)

    Thapa, Damber; Raahemifar, Kaamran; Lakshminarayanan, Vasudevan

    2015-12-01

    In this paper, we propose a speckle noise reduction method for spectral-domain optical coherence tomography (SD-OCT) images called multi-frame weighted nuclear norm minimization (MWNNM). This method is a direct extension of weighted nuclear norm minimization (WNNM) in the multi-frame framework since an adequately denoised image could not be achieved with single-frame denoising methods. The MWNNM method exploits multiple B-scans collected from a small area of a SD-OCT volumetric image, and then denoises and averages them together to obtain a high signal-to-noise ratio B-scan. The results show that the image quality metrics obtained by denoising and averaging only five nearby B-scans with MWNNM method is considerably better than those of the average image obtained by registering and averaging 40 azimuthally repeated B-scans.

  13. Seismic data restoration with a fast L1 norm trust region method

    NASA Astrophysics Data System (ADS)

    Cao, Jingjie; Wang, Yanfei

    2014-08-01

    Seismic data restoration is a major strategy to provide reliable wavefield when field data dissatisfy the Shannon sampling theorem. Recovery by sparsity-promoting inversion often get sparse solutions of seismic data in a transformed domains, however, most methods for sparsity-promoting inversion are line-searching methods which are efficient but are inclined to obtain local solutions. Using trust region method which can provide globally convergent solutions is a good choice to overcome this shortcoming. A trust region method for sparse inversion has been proposed, however, the efficiency should be improved to suitable for large-scale computation. In this paper, a new L1 norm trust region model is proposed for seismic data restoration and a robust gradient projection method for solving the sub-problem is utilized. Numerical results of synthetic and field data demonstrate that the proposed trust region method can get excellent computation speed and is a viable alternative for large-scale computation.

  14. Stabilizing l1-norm prediction models by supervised feature grouping.

    PubMed

    Kamkar, Iman; Gupta, Sunil Kumar; Phung, Dinh; Venkatesh, Svetha

    2016-02-01

    Emerging Electronic Medical Records (EMRs) have reformed the modern healthcare. These records have great potential to be used for building clinical prediction models. However, a problem in using them is their high dimensionality. Since a lot of information may not be relevant for prediction, the underlying complexity of the prediction models may not be high. A popular way to deal with this problem is to employ feature selection. Lasso and l1-norm based feature selection methods have shown promising results. But, in presence of correlated features, these methods select features that change considerably with small changes in data. This prevents clinicians to obtain a stable feature set, which is crucial for clinical decision making. Grouping correlated variables together can improve the stability of feature selection, however, such grouping is usually not known and needs to be estimated for optimal performance. Addressing this problem, we propose a new model that can simultaneously learn the grouping of correlated features and perform stable feature selection. We formulate the model as a constrained optimization problem and provide an efficient solution with guaranteed convergence. Our experiments with both synthetic and real-world datasets show that the proposed model is significantly more stable than Lasso and many existing state-of-the-art shrinkage and classification methods. We further show that in terms of prediction performance, the proposed method consistently outperforms Lasso and other baselines. Our model can be used for selecting stable risk factors for a variety of healthcare problems, so it can assist clinicians toward accurate decision making. Copyright © 2015 Elsevier Inc. All rights reserved.

  15. 1-norm support vector novelty detection and its sparseness.

    PubMed

    Zhang, Li; Zhou, WeiDa

    2013-12-01

    This paper proposes a 1-norm support vector novelty detection (SVND) method and discusses its sparseness. 1-norm SVND is formulated as a linear programming problem and uses two techniques for inducing sparseness, or the 1-norm regularization and the hinge loss function. We also find two upper bounds on the sparseness of 1-norm SVND, or exact support vector (ESV) and kernel Gram matrix rank bounds. The ESV bound indicates that 1-norm SVND has a sparser representation model than SVND. The kernel Gram matrix rank bound can loosely estimate the sparseness of 1-norm SVND. Experimental results show that 1-norm SVND is feasible and effective. Copyright © 2013 Elsevier Ltd. All rights reserved.

  16. Two conditions for equivalence of 0-norm solution and 1-norm solution in sparse representation.

    PubMed

    Li, Yuanqing; Amari, Shun-Ichi

    2010-07-01

    In sparse representation, two important sparse solutions, the 0-norm and 1-norm solutions, have been receiving much of attention. The 0-norm solution is the sparsest, however it is not easy to obtain. Although the 1-norm solution may not be the sparsest, it can be easily obtained by the linear programming method. In many cases, the 0-norm solution can be obtained through finding the 1-norm solution. Many discussions exist on the equivalence of the two sparse solutions. This paper analyzes two conditions for the equivalence of the two sparse solutions. The first condition is necessary and sufficient, however, difficult to verify. Although the second is necessary but is not sufficient, it is easy to verify. In this paper, we analyze the second condition within the stochastic framework and propose a variant. We then prove that the equivalence of the two sparse solutions holds with high probability under the variant of the second condition. Furthermore, in the limit case where the 0-norm solution is extremely sparse, the second condition is also a sufficient condition with probability 1.

  17. Joint L1 and Total Variation Regularization for Fluorescence Molecular Tomography

    PubMed Central

    Dutta, Joyita; Ahn, Sangtae; Li, Changqing; Cherry, Simon R.; Leahy, Richard M.

    2012-01-01

    Fluorescence molecular tomography (FMT) is an imaging modality that exploits the specificity of fluorescent biomarkers to enable 3D visualization of molecular targets and pathways in vivo in small animals. Owing to the high degree of absorption and scattering of light through tissue, the FMT inverse problem is inherently illconditioned making image reconstruction highly susceptible to the effects of noise and numerical errors. Appropriate priors or penalties are needed to facilitate reconstruction and to restrict the search space to a specific solution set. Typically, fluorescent probes are locally concentrated within specific areas of interest (e.g., inside tumors). The commonly used L2 norm penalty generates the minimum energy solution, which tends to be spread out in space. Instead, we present here an approach involving a combination of the L1 and total variation norm penalties, the former to suppress spurious background signals and enforce sparsity and the latter to preserve local smoothness and piecewise constancy in the reconstructed images. We have developed a surrogate-based optimization method for minimizing the joint penalties. The method was validated using both simulated and experimental data obtained from a mouse-shaped phantom mimicking tissue optical properties and containing two embedded fluorescent sources. Fluorescence data was collected using a 3D FMT setup that uses an EMCCD camera for image acquisition and a conical mirror for full-surface viewing. A range of performance metrics were utilized to evaluate our simulation results and to compare our method with the L1, L2, and total variation norm penalty based approaches. The experimental results were assessed using Dice similarity coefficients computed after co-registration with a CT image of the phantom. PMID:22390906

  18. Quantum Ergodicity and L p Norms of Restrictions of Eigenfunctions

    NASA Astrophysics Data System (ADS)

    Hezari, Hamid

    2018-02-01

    We prove an analogue of Sogge's local L p estimates for L p norms of restrictions of eigenfunctions to submanifolds, and use it to show that for quantum ergodic eigenfunctions one can get improvements of the results of Burq-Gérard-Tzvetkov, Hu, and Chen-Sogge. The improvements are logarithmic on negatively curved manifolds (without boundary) and by o(1) for manifolds (with or without boundary) with ergodic geodesic flows. In the case of ergodic billiards with piecewise smooth boundary, we get o(1) improvements on L^∞ estimates of Cauchy data away from a shrinking neighborhood of the corners, and as a result using the methods of Ghosh et al., Jung and Zelditch, Jung and Zelditch, we get that the number of nodal domains of 2-dimensional ergodic billiards tends to infinity as λ \\to ∞. These results work only for a full density subsequence of any given orthonormal basis of eigenfunctions. We also present an extension of the L p estimates of Burq-Gérard-Tzvetkov, Hu, Chen-Sogge for the restrictions of Dirichlet and Neumann eigenfunctions to compact submanifolds of the interior of manifolds with piecewise smooth boundary. This part does not assume ergodicity on the manifolds.

  19. Exploring L1 model space in search of conductivity bounds for the MT problem

    NASA Astrophysics Data System (ADS)

    Wheelock, B. D.; Parker, R. L.

    2013-12-01

    Geophysical inverse problems of the type encountered in electromagnetic techniques are highly non-unique. As a result, any single inverted model, though feasible, is at best inconclusive and at worst misleading. In this paper, we use modified inversion methods to establish bounds on electrical conductivity within a model of the earth. Our method consists of two steps, each making use of the 1-norm in model regularization. Both 1-norm minimization problems are framed without approximation as non-negative least-squares (NNLS) problems. First, we must identify a parsimonious set of regions within the model for which upper and lower bounds on average conductivity will be sought. This is accomplished by minimizing the 1-norm of spatial variation, which produces a model with a limited number of homogeneous regions; in fact, the number of homogeneous regions will never be greater than the number of data, regardless of the number of free parameters supplied. The second step establishes bounds for each of these regions with pairs of inversions. The new suite of inversions also uses a 1-norm penalty, but applied to the conductivity values themselves, rather than the spatial variation thereof. In the bounding step we use the 1-norm of our model parameters because it is proportional to average conductivity. For a lower bound on average conductivity, the 1-norm within a bounding region is minimized. For an upper bound on average conductivity, the 1-norm everywhere outside a bounding region is minimized. The latter minimization has the effect of concentrating conductance into the bounding region. Taken together, these bounds are a measure of the uncertainty in the associated region of our model. Starting with a blocky inverse solution is key in the selection of the bounding regions. Of course, there is a tradeoff between resolution and uncertainty: an increase in resolution (smaller bounding regions), results in greater uncertainty (wider bounds). Minimization of the 1-norm of

  20. On the sparseness of 1-norm support vector machines.

    PubMed

    Zhang, Li; Zhou, Weida

    2010-04-01

    There is some empirical evidence available showing that 1-norm Support Vector Machines (1-norm SVMs) have good sparseness; however, both how good sparseness 1-norm SVMs can reach and whether they have a sparser representation than that of standard SVMs are not clear. In this paper we take into account the sparseness of 1-norm SVMs. Two upper bounds on the number of nonzero coefficients in the decision function of 1-norm SVMs are presented. First, the number of nonzero coefficients in 1-norm SVMs is at most equal to the number of only the exact support vectors lying on the +1 and -1 discriminating surfaces, while that in standard SVMs is equal to the number of support vectors, which implies that 1-norm SVMs have better sparseness than that of standard SVMs. Second, the number of nonzero coefficients is at most equal to the rank of the sample matrix. A brief review of the geometry of linear programming and the primal steepest edge pricing simplex method are given, which allows us to provide the proof of the two upper bounds and evaluate their tightness by experiments. Experimental results on toy data sets and the UCI data sets illustrate our analysis. Copyright 2009 Elsevier Ltd. All rights reserved.

  1. Rational Approximations with Hankel-Norm Criterion

    DTIC Science & Technology

    1980-01-01

    REPORT TYPE ANDu DATES COVERED It) L. TITLE AND SLWUIlL Fi901 ia FUNDING NUMOIRS, RATIONAL APPROXIMATIONS WITH HANKEL-NORM CRITERION PE61102F i...problem is proved to be reducible to obtain a two-variable all- pass ration 1 function, interpolating a set of parametric values at specified points inside...PAGES WHICH DO NOT REPRODUCE LEGIBLY. V" C - w RATIONAL APPROXIMATIONS WITH HANKEL-NORM CRITERION* Y. Genin* Philips Research Lab. 2, avenue van

  2. Manifold optimization-based analysis dictionary learning with an ℓ1∕2-norm regularizer.

    PubMed

    Li, Zhenni; Ding, Shuxue; Li, Yujie; Yang, Zuyuan; Xie, Shengli; Chen, Wuhui

    2018-02-01

    Recently there has been increasing attention towards analysis dictionary learning. In analysis dictionary learning, it is an open problem to obtain the strong sparsity-promoting solutions efficiently while simultaneously avoiding the trivial solutions of the dictionary. In this paper, to obtain the strong sparsity-promoting solutions, we employ the ℓ 1∕2 norm as a regularizer. The very recent study on ℓ 1∕2 norm regularization theory in compressive sensing shows that its solutions can give sparser results than using the ℓ 1 norm. We transform a complex nonconvex optimization into a number of one-dimensional minimization problems. Then the closed-form solutions can be obtained efficiently. To avoid trivial solutions, we apply manifold optimization to update the dictionary directly on the manifold satisfying the orthonormality constraint, so that the dictionary can avoid the trivial solutions well while simultaneously capturing the intrinsic properties of the dictionary. The experiments with synthetic and real-world data verify that the proposed algorithm for analysis dictionary learning can not only obtain strong sparsity-promoting solutions efficiently, but also learn more accurate dictionary in terms of dictionary recovery and image processing than the state-of-the-art algorithms. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. L2-norm multiple kernel learning and its application to biomedical data fusion

    PubMed Central

    2010-01-01

    Background This paper introduces the notion of optimizing different norms in the dual problem of support vector machines with multiple kernels. The selection of norms yields different extensions of multiple kernel learning (MKL) such as L∞, L1, and L2 MKL. In particular, L2 MKL is a novel method that leads to non-sparse optimal kernel coefficients, which is different from the sparse kernel coefficients optimized by the existing L∞ MKL method. In real biomedical applications, L2 MKL may have more advantages over sparse integration method for thoroughly combining complementary information in heterogeneous data sources. Results We provide a theoretical analysis of the relationship between the L2 optimization of kernels in the dual problem with the L2 coefficient regularization in the primal problem. Understanding the dual L2 problem grants a unified view on MKL and enables us to extend the L2 method to a wide range of machine learning problems. We implement L2 MKL for ranking and classification problems and compare its performance with the sparse L∞ and the averaging L1 MKL methods. The experiments are carried out on six real biomedical data sets and two large scale UCI data sets. L2 MKL yields better performance on most of the benchmark data sets. In particular, we propose a novel L2 MKL least squares support vector machine (LSSVM) algorithm, which is shown to be an efficient and promising classifier for large scale data sets processing. Conclusions This paper extends the statistical framework of genomic data fusion based on MKL. Allowing non-sparse weights on the data sources is an attractive option in settings where we believe most data sources to be relevant to the problem at hand and want to avoid a "winner-takes-all" effect seen in L∞ MKL, which can be detrimental to the performance in prospective studies. The notion of optimizing L2 kernels can be straightforwardly extended to ranking, classification, regression, and clustering algorithms. To tackle the

  4. Contrast adaptive total p-norm variation minimization approach to CT reconstruction for artifact reduction in reduced-view brain perfusion CT

    NASA Astrophysics Data System (ADS)

    Kim, Chang-Won; Kim, Jong-Hyo

    2011-03-01

    Perfusion CT (PCT) examinations are getting more frequently used for diagnosis of acute brain diseases such as hemorrhage and infarction, because the functional map images it produces such as regional cerebral blood flow (rCBF), regional cerebral blood volume (rCBV), and mean transit time (MTT) may provide critical information in the emergency work-up of patient care. However, a typical PCT scans the same slices several tens of times after injection of contrast agent, which leads to much increased radiation dose and is inevitability of growing concern for radiation-induced cancer risk. Reducing the number of views in projection in combination of TV minimization reconstruction technique is being regarded as an option for radiation reduction. However, reconstruction artifacts due to insufficient number of X-ray projections become problematic especially when high contrast enhancement signals are present or patient's motion occurred. In this study, we present a novel reconstruction technique using contrast-adaptive TpV minimization that can reduce reconstruction artifacts effectively by using different p-norms in high contrast and low contrast objects. In the proposed method, high contrast components are first reconstructed using thresholded projection data and low p-norm total variation to reflect sparseness in both projection and reconstruction spaces. Next, projection data are modified to contain only low contrast objects by creating projection data of reconstructed high contrast components and subtracting them from original projection data. Then, the low contrast projection data are reconstructed by using relatively high p-norm TV minimization technique, and are combined with the reconstructed high contrast component images to produce final reconstructed images. The proposed algorithm was applied to numerical phantom and a clinical data set of brain PCT exam, and the resultant images were compared with those using filtered back projection (FBP) and conventional TV

  5. Validity of the EQ-5D-5L and reference norms for the Spanish population.

    PubMed

    Hernandez, Gimena; Garin, Olatz; Pardo, Yolanda; Vilagut, Gemma; Pont, Àngels; Suárez, Mónica; Neira, Montse; Rajmil, Luís; Gorostiza, Inigo; Ramallo-Fariña, Yolanda; Cabases, Juan; Alonso, Jordi; Ferrer, Montse

    2018-05-16

    The EuroQol 5 dimensions 5 levels (EQ-5D-5L) is the new version of EQ-5D, developed to improve its discriminatory capacity. This study aims to evaluate the construct validity of the Spanish version and provide index and dimension population-based reference norms for the new EQ-5D-5L. Data were obtained from the 2011/2012 Spanish National Health Survey, with a representative sample (n = 20,587) of non-institutionalized Spanish adults (≥ 18 years). The EQ-5D-5L index was calculated by using the Spanish value set. Construct validity was evaluated by comparing known groups with estimators obtained through regression models, adjusted by age and gender. Sampling weights were applied to restore the representativeness of the sample and to calculate the norms stratified by gender and age groups. We calculated the percentages and standard errors of dimensions, and the deciles, percentiles 5 and 95, means, and 95% confidence intervals of the health index. All the hypotheses established a priori for known groups were confirmed (P < 0.001). The EQ-5D-5L index indicated worse health in groups with lower education level (from 0.94 to 0.87), higher number of chronic conditions (0.96-0.79), probable psychiatric disorder (0.94 vs 0.80), strong limitations (0.96-0.46), higher number of days of restriction (0.93-0.64) or confinement to bed (0.92-0.49), and hospitalized in the previous 12 months (0.92 vs 0.81). The EQ-5D-5L is a valid instrument to measure perceived health in the Spanish-speaking population. The representative population-based norms provided here will help improve the interpretation of results obtained with the new EQ-5D-5L.

  6. Translation norms for English and Spanish: The role of lexical variables, word class, and L2 proficiency in negotiating translation ambiguity

    PubMed Central

    Prior, Anat; MacWhinney, Brian; Kroll, Judith F.

    2014-01-01

    We present a set of translation norms for 670 English and 760 Spanish nouns, verbs and class ambiguous items that varied in their lexical properties in both languages, collected from 80 bilingual participants. Half of the words in each language received more than a single translation across participants. Cue word frequency and imageability were both negatively correlated with number of translations. Word class predicted number of translations: Nouns had fewer translations than did verbs, which had fewer translations than class-ambiguous items. The translation probability of specific responses was positively correlated with target word frequency and imageability, and with its form overlap with the cue word. Translation choice was modulated by L2 proficiency: Less proficient bilinguals tended to produce lower probability translations than more proficient bilinguals, but only in forward translation, from L1 to L2. These findings highlight the importance of translation ambiguity as a factor influencing bilingual representation and performance. The norms can also provide an important resource to assist researchers in the selection of experimental materials for studies of bilingual and monolingual language performance. These norms may be downloaded from www.psychonomic.org/archive. PMID:18183923

  7. Comparison of l₁-Norm SVR and Sparse Coding Algorithms for Linear Regression.

    PubMed

    Zhang, Qingtian; Hu, Xiaolin; Zhang, Bo

    2015-08-01

    Support vector regression (SVR) is a popular function estimation technique based on Vapnik's concept of support vector machine. Among many variants, the l1-norm SVR is known to be good at selecting useful features when the features are redundant. Sparse coding (SC) is a technique widely used in many areas and a number of efficient algorithms are available. Both l1-norm SVR and SC can be used for linear regression. In this brief, the close connection between the l1-norm SVR and SC is revealed and some typical algorithms are compared for linear regression. The results show that the SC algorithms outperform the Newton linear programming algorithm, an efficient l1-norm SVR algorithm, in efficiency. The algorithms are then used to design the radial basis function (RBF) neural networks. Experiments on some benchmark data sets demonstrate the high efficiency of the SC algorithms. In particular, one of the SC algorithms, the orthogonal matching pursuit is two orders of magnitude faster than a well-known RBF network designing algorithm, the orthogonal least squares algorithm.

  8. What's in a norm? Sources and processes of norm change.

    PubMed

    Paluck, Elizabeth Levy

    2009-03-01

    This reply to the commentary by E. Staub and L. A. Pearlman (2009) revisits the field experimental results of E. L. Paluck (2009). It introduces further evidence and theoretical elaboration supporting Paluck's conclusion that exposure to a reconciliation-themed radio soap opera changed perceptions of social norms and behaviors, not beliefs. Experimental and longitudinal survey evidence reinforces the finding that the radio program affected socially shared perceptions of typical or prescribed behavior-that is, social norms. Specifically, measurements of perceptions of social norms called into question by Staub and Pearlman are shown to correlate with perceptions of public opinion and public, not private, behaviors. Although measurement issues and the mechanisms of the radio program's influence merit further testing, theory and evidence point to social interactions and emotional engagement, not individual education, as the likely mechanisms of change. The present exchange makes salient what is at stake in this debate: a model of change based on learning and personal beliefs versus a model based on group influence and social norms. These theoretical models recommend very different strategies for prejudice and conflict reduction. Future field experiments should attempt to adjudicate between these models by testing relevant policies in real-world settings.

  9. A unified framework for penalized statistical muon tomography reconstruction with edge preservation priors of lp norm type

    NASA Astrophysics Data System (ADS)

    Yu, Baihui; Zhao, Ziran; Wang, Xuewu; Wu, Dufan; Zeng, Zhi; Zeng, Ming; Wang, Yi; Cheng, Jianping

    2016-01-01

    The Tsinghua University MUon Tomography facilitY (TUMUTY) has been built up and it is utilized to reconstruct the special objects with complex structure. Since fine image is required, the conventional Maximum likelihood Scattering and Displacement (MLSD) algorithm is employed. However, due to the statistical characteristics of muon tomography and the data incompleteness, the reconstruction is always instable and accompanied with severe noise. In this paper, we proposed a Maximum a Posterior (MAP) algorithm for muon tomography regularization, where an edge-preserving prior on the scattering density image is introduced to the object function. The prior takes the lp norm (p>0) of the image gradient magnitude, where p=1 and p=2 are the well-known total-variation (TV) and Gaussian prior respectively. The optimization transfer principle is utilized to minimize the object function in a unified framework. At each iteration the problem is transferred to solving a cubic equation through paraboloidal surrogating. To validate the method, the French Test Object (FTO) is imaged by both numerical simulation and TUMUTY. The proposed algorithm is used for the reconstruction where different norms are detailedly studied, including l2, l1, l0.5, and an l2-0.5 mixture norm. Compared with MLSD method, MAP achieves better image quality in both structure preservation and noise reduction. Furthermore, compared with the previous work where one dimensional image was acquired, we achieve the relatively clear three dimensional images of FTO, where the inner air hole and the tungsten shell is visible.

  10. A new smoothing modified three-term conjugate gradient method for [Formula: see text]-norm minimization problem.

    PubMed

    Du, Shouqiang; Chen, Miao

    2018-01-01

    We consider a kind of nonsmooth optimization problems with [Formula: see text]-norm minimization, which has many applications in compressed sensing, signal reconstruction, and the related engineering problems. Using smoothing approximate techniques, this kind of nonsmooth optimization problem can be transformed into a general unconstrained optimization problem, which can be solved by the proposed smoothing modified three-term conjugate gradient method. The smoothing modified three-term conjugate gradient method is based on Polak-Ribière-Polyak conjugate gradient method. For the Polak-Ribière-Polyak conjugate gradient method has good numerical properties, the proposed method possesses the sufficient descent property without any line searches, and it is also proved to be globally convergent. Finally, the numerical experiments show the efficiency of the proposed method.

  11. MEG source imaging method using fast L1 minimum-norm and its applications to signals with brain noise and human resting-state source amplitude images.

    PubMed

    Huang, Ming-Xiong; Huang, Charles W; Robb, Ashley; Angeles, AnneMarie; Nichols, Sharon L; Baker, Dewleen G; Song, Tao; Harrington, Deborah L; Theilmann, Rebecca J; Srinivasan, Ramesh; Heister, David; Diwakar, Mithun; Canive, Jose M; Edgar, J Christopher; Chen, Yu-Han; Ji, Zhengwei; Shen, Max; El-Gabalawy, Fady; Levy, Michael; McLay, Robert; Webb-Murphy, Jennifer; Liu, Thomas T; Drake, Angela; Lee, Roland R

    2014-01-01

    The present study developed a fast MEG source imaging technique based on Fast Vector-based Spatio-Temporal Analysis using a L1-minimum-norm (Fast-VESTAL) and then used the method to obtain the source amplitude images of resting-state magnetoencephalography (MEG) signals for different frequency bands. The Fast-VESTAL technique consists of two steps. First, L1-minimum-norm MEG source images were obtained for the dominant spatial modes of sensor-waveform covariance matrix. Next, accurate source time-courses with millisecond temporal resolution were obtained using an inverse operator constructed from the spatial source images of Step 1. Using simulations, Fast-VESTAL's performance was assessed for its 1) ability to localize multiple correlated sources; 2) ability to faithfully recover source time-courses; 3) robustness to different SNR conditions including SNR with negative dB levels; 4) capability to handle correlated brain noise; and 5) statistical maps of MEG source images. An objective pre-whitening method was also developed and integrated with Fast-VESTAL to remove correlated brain noise. Fast-VESTAL's performance was then examined in the analysis of human median-nerve MEG responses. The results demonstrated that this method easily distinguished sources in the entire somatosensory network. Next, Fast-VESTAL was applied to obtain the first whole-head MEG source-amplitude images from resting-state signals in 41 healthy control subjects, for all standard frequency bands. Comparisons between resting-state MEG sources images and known neurophysiology were provided. Additionally, in simulations and cases with MEG human responses, the results obtained from using conventional beamformer technique were compared with those from Fast-VESTAL, which highlighted the beamformer's problems of signal leaking and distorted source time-courses. © 2013.

  12. Naturally Occurring Radioactive Materials (NORM)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gray, P.

    1997-02-01

    This paper discusses the broad problems presented by Naturally Occuring Radioactive Materials (NORM). Technologically Enhanced naturally occuring radioactive material includes any radionuclides whose physical, chemical, radiological properties or radionuclide concentration have been altered from their natural state. With regard to NORM in particular, radioactive contamination is radioactive material in an undesired location. This is a concern in a range of industries: petroleum; uranium mining; phosphorus and phosphates; fertilizers; fossil fuels; forestry products; water treatment; metal mining and processing; geothermal energy. The author discusses in more detail the problem in the petroleum industry, including the isotopes of concern, the hazards theymore » present, the contamination which they cause, ways to dispose of contaminated materials, and regulatory issues. He points out there are three key programs to reduce legal exposure and problems due to these contaminants: waste minimization; NORM assesment (surveys); NORM compliance (training).« less

  13. Joint L2,1 Norm and Fisher Discrimination Constrained Feature Selection for Rational Synthesis of Microporous Aluminophosphates.

    PubMed

    Qi, Miao; Wang, Ting; Yi, Yugen; Gao, Na; Kong, Jun; Wang, Jianzhong

    2017-04-01

    Feature selection has been regarded as an effective tool to help researchers understand the generating process of data. For mining the synthesis mechanism of microporous AlPOs, this paper proposes a novel feature selection method by joint l 2,1 norm and Fisher discrimination constraints (JNFDC). In order to obtain more effective feature subset, the proposed method can be achieved in two steps. The first step is to rank the features according to sparse and discriminative constraints. The second step is to establish predictive model with the ranked features, and select the most significant features in the light of the contribution of improving the predictive accuracy. To the best of our knowledge, JNFDC is the first work which employs the sparse representation theory to explore the synthesis mechanism of six kinds of pore rings. Numerical simulations demonstrate that our proposed method can select significant features affecting the specified structural property and improve the predictive accuracy. Moreover, comparison results show that JNFDC can obtain better predictive performances than some other state-of-the-art feature selection methods. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. An experimental clinical evaluation of EIT imaging with ℓ1 data and image norms.

    PubMed

    Mamatjan, Yasin; Borsic, Andrea; Gürsoy, Doga; Adler, Andy

    2013-09-01

    Electrical impedance tomography (EIT) produces an image of internal conductivity distributions in a body from current injection and electrical measurements at surface electrodes. Typically, image reconstruction is formulated using regularized schemes in which ℓ2-norms are used for both data misfit and image prior terms. Such a formulation is computationally convenient, but favours smooth conductivity solutions and is sensitive to outliers. Recent studies highlighted the potential of ℓ1-norm and provided the mathematical basis to improve image quality and robustness of the images to data outliers. In this paper, we (i) extended a primal-dual interior point method (PDIPM) algorithm to 2.5D EIT image reconstruction to solve ℓ1 and mixed ℓ1/ℓ2 formulations efficiently, (ii) evaluated the formulation on clinical and experimental data, and (iii) developed a practical strategy to select hyperparameters using the L-curve which requires minimum user-dependence. The PDIPM algorithm was evaluated using clinical and experimental scenarios on human lung and dog breathing with known electrode errors, which requires a rigorous regularization and causes the failure of reconstruction with an ℓ2-norm solution. The results showed that an ℓ1 solution is not only more robust to unavoidable measurement errors in a clinical setting, but it also provides high contrast resolution on organ boundaries.

  15. NEIGHBORHOOD NORMS AND SUBSTANCE USE AMONG TEENS

    PubMed Central

    Musick, Kelly; Seltzer, Judith A.; Schwartz, Christine R.

    2008-01-01

    This paper uses new data from the Los Angeles Family and Neighborhood Survey (L.A. FANS) to examine how neighborhood norms shape teenagers’ substance use. Specifically, it takes advantage of clustered data at the neighborhood level to relate adult neighbors’ attitudes and behavior with respect to smoking, drinking, and drugs, which we treat as norms, to teenagers’ own smoking, drinking, and drug use. We use hierarchical linear models to account for parents’ attitudes and behavior and other characteristics of individuals and families. We also investigate how the association between neighborhood norms and teen behavior depends on: (1) the strength of norms, as measured by consensus in neighbors’ attitudes and conformity in their behavior; (2) the willingness and ability of neighbors to enforce norms, for instance, by monitoring teens’ activities; and (3) the degree to which teens are exposed to their neighbors. We find little association between neighborhood norms and teen substance use, regardless of how we condition the relationship. We discuss possible theoretical and methodological explanations for this finding. PMID:18496598

  16. Improved l1-SPIRiT using 3D walsh transform-based sparsity basis.

    PubMed

    Feng, Zhen; Liu, Feng; Jiang, Mingfeng; Crozier, Stuart; Guo, He; Wang, Yuxin

    2014-09-01

    l1-SPIRiT is a fast magnetic resonance imaging (MRI) method which combines parallel imaging (PI) with compressed sensing (CS) by performing a joint l1-norm and l2-norm optimization procedure. The original l1-SPIRiT method uses two-dimensional (2D) Wavelet transform to exploit the intra-coil data redundancies and a joint sparsity model to exploit the inter-coil data redundancies. In this work, we propose to stack all the coil images into a three-dimensional (3D) matrix, and then a novel 3D Walsh transform-based sparsity basis is applied to simultaneously reduce the intra-coil and inter-coil data redundancies. Both the 2D Wavelet transform-based and the proposed 3D Walsh transform-based sparsity bases were investigated in the l1-SPIRiT method. The experimental results show that the proposed 3D Walsh transform-based l1-SPIRiT method outperformed the original l1-SPIRiT in terms of image quality and computational efficiency. Copyright © 2014 Elsevier Inc. All rights reserved.

  17. MEG Source Imaging Method using Fast L1 Minimum-norm and its Applications to Signals with Brain Noise and Human Resting-state Source Amplitude Images

    PubMed Central

    Huang, Ming-Xiong; Huang, Charles W.; Robb, Ashley; Angeles, AnneMarie; Nichols, Sharon L.; Baker, Dewleen G.; Song, Tao; Harrington, Deborah L.; Theilmann, Rebecca J.; Srinivasan, Ramesh; Heister, David; Diwakar, Mithun; Canive, Jose M.; Edgar, J. Christopher; Chen, Yu-Han; Ji, Zhengwei; Shen, Max; El-Gabalawy, Fady; Levy, Michael; McLay, Robert; Webb-Murphy, Jennifer; Liu, Thomas T.; Drake, Angela; Lee, Roland R.

    2014-01-01

    The present study developed a fast MEG source imaging technique based on Fast Vector-based Spatio-Temporal Analysis using a L1-minimum-norm (Fast-VESTAL) and then used the method to obtain the source amplitude images of resting-state magnetoencephalography (MEG) signals for different frequency bands. The Fast-VESTAL technique consists of two steps. First, L1-minimum-norm MEG source images were obtained for the dominant spatial modes of sensor-waveform covariance matrix. Next, accurate source time-courses with millisecond temporal resolution were obtained using an inverse operator constructed from the spatial source images of Step 1. Using simulations, Fast-VESTAL’s performance of was assessed for its 1) ability to localize multiple correlated sources; 2) ability to faithfully recover source time-courses; 3) robustness to different SNR conditions including SNR with negative dB levels; 4) capability to handle correlated brain noise; and 5) statistical maps of MEG source images. An objective pre-whitening method was also developed and integrated with Fast-VESTAL to remove correlated brain noise. Fast-VESTAL’s performance was then examined in the analysis of human mediannerve MEG responses. The results demonstrated that this method easily distinguished sources in the entire somatosensory network. Next, Fast-VESTAL was applied to obtain the first whole-head MEG source-amplitude images from resting-state signals in 41 healthy control subjects, for all standard frequency bands. Comparisons between resting-state MEG sources images and known neurophysiology were provided. Additionally, in simulations and cases with MEG human responses, the results obtained from using conventional beamformer technique were compared with those from Fast-VESTAL, which highlighted the beamformer’s problems of signal leaking and distorted source time-courses. PMID:24055704

  18. Population norms for the AQoL derived from the 2007 Australian National Survey of Mental Health and Wellbeing.

    PubMed

    Hawthorne, Graeme; Korn, Sam; Richardson, Jeff

    2013-02-01

    To provide Australian health-related quality of life (HRQoL) population norms, based on utility scores from the Assessment of Quality of Life (AQoL) measure, a participant-reported outcomes (PRO) instrument. The data were from the 2007 National Survey of Mental Health and Wellbeing. AQoL scores were analysed by age cohorts, gender, other demographic characteristics, and mental and physical health variables. The AQoL utility score mean was 0.81 (95%CI 0.81-0.82), and 47% obtained scores indicating a very high HRQoL (>0.90). HRQoL gently declined by age group, with older adults' scores indicating lower HRQoL. Based on effect sizes (ESs), there were small losses in HRQoL associated with other demographic variables (e.g. by lack of labour force participation, ES(median) : 0.27). Those with current mental health syndromes reported moderate losses in HRQoL (ES(median) : 0.64), while those with physical health conditions generally also reported moderate losses in HRQoL (ES(median) : 0.41). This study has provided contemporary Australian population norms for HRQoL that may be used by researchers as indicators allowing interpretation and estimation of population health (e.g. estimation of the burden of disease), cross comparison between studies, the identification of health inequalities, and to provide benchmarks for health care interventions. © 2013 The Authors. ANZJPH © 2013 Public Health Association of Australia.

  19. Metric freeness and projectivity for classical and quantum normed modules

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Helemskii, A Ya

    2013-07-31

    In functional analysis, there are several diverse approaches to the notion of projective module. We show that a certain general categorical scheme contains all basic versions as special cases. In this scheme, the notion of free object comes to the foreground, and, in the best categories, projective objects are precisely retracts of free ones. We are especially interested in the so-called metric version of projectivity and characterize the metrically free classical and quantum (= operator) normed modules. Informally speaking, so-called extremal projectivity, which was known earlier, is interpreted as a kind of 'asymptotical metric projectivity'. In addition, we answer themore » following specific question in the geometry of normed spaces: what is the structure of metrically projective modules in the simplest case of normed spaces? We prove that metrically projective normed spaces are precisely the subspaces of l{sub 1}(M) (where M is a set) that are denoted by l{sub 1}{sup 0}(M) and consist of finitely supported functions. Thus, in this case, projectivity coincides with freeness. Bibliography: 28 titles.« less

  20. Trace Norm Regularized CANDECOMP/PARAFAC Decomposition With Missing Data.

    PubMed

    Liu, Yuanyuan; Shang, Fanhua; Jiao, Licheng; Cheng, James; Cheng, Hong

    2015-11-01

    In recent years, low-rank tensor completion (LRTC) problems have received a significant amount of attention in computer vision, data mining, and signal processing. The existing trace norm minimization algorithms for iteratively solving LRTC problems involve multiple singular value decompositions of very large matrices at each iteration. Therefore, they suffer from high computational cost. In this paper, we propose a novel trace norm regularized CANDECOMP/PARAFAC decomposition (TNCP) method for simultaneous tensor decomposition and completion. We first formulate a factor matrix rank minimization model by deducing the relation between the rank of each factor matrix and the mode- n rank of a tensor. Then, we introduce a tractable relaxation of our rank function, and then achieve a convex combination problem of much smaller-scale matrix trace norm minimization. Finally, we develop an efficient algorithm based on alternating direction method of multipliers to solve our problem. The promising experimental results on synthetic and real-world data validate the effectiveness of our TNCP method. Moreover, TNCP is significantly faster than the state-of-the-art methods and scales to larger problems.

  1. Extending the Mertonian Norms: Scientists' Subscription to Norms of Research

    ERIC Educational Resources Information Center

    Anderson, Melissa S.; Ronning, Emily A.; De Vries, Raymond; Martinson, Brian C.

    2010-01-01

    This analysis, based on focus groups and a national survey, assesses scientists' subscription to the Mertonian norms of science and associated counternorms. It also supports extension of these norms to governance (as opposed to administration), as a norm of decision-making, and quality (as opposed to quantity), as an evaluative norm. (Contains 1

  2. Improving absolute gravity estimates by the L p -norm approximation of the ballistic trajectory

    NASA Astrophysics Data System (ADS)

    Nagornyi, V. D.; Svitlov, S.; Araya, A.

    2016-04-01

    Iteratively re-weighted least squares (IRLS) were used to simulate the L p -norm approximation of the ballistic trajectory in absolute gravimeters. Two iterations of the IRLS delivered sufficient accuracy of the approximation without a significant bias. The simulations were performed on different samplings and perturbations of the trajectory. For the platykurtic distributions of the perturbations, the L p -approximation with 3  <  p  <  4 was found to yield several times more precise gravity estimates compared to the standard least-squares. The simulation results were confirmed by processing real gravity observations performed at the excessive noise conditions.

  3. Fast and accurate matrix completion via truncated nuclear norm regularization.

    PubMed

    Hu, Yao; Zhang, Debing; Ye, Jieping; Li, Xuelong; He, Xiaofei

    2013-09-01

    Recovering a large matrix from a small subset of its entries is a challenging problem arising in many real applications, such as image inpainting and recommender systems. Many existing approaches formulate this problem as a general low-rank matrix approximation problem. Since the rank operator is nonconvex and discontinuous, most of the recent theoretical studies use the nuclear norm as a convex relaxation. One major limitation of the existing approaches based on nuclear norm minimization is that all the singular values are simultaneously minimized, and thus the rank may not be well approximated in practice. In this paper, we propose to achieve a better approximation to the rank of matrix by truncated nuclear norm, which is given by the nuclear norm subtracted by the sum of the largest few singular values. In addition, we develop a novel matrix completion algorithm by minimizing the Truncated Nuclear Norm. We further develop three efficient iterative procedures, TNNR-ADMM, TNNR-APGL, and TNNR-ADMMAP, to solve the optimization problem. TNNR-ADMM utilizes the alternating direction method of multipliers (ADMM), while TNNR-AGPL applies the accelerated proximal gradient line search method (APGL) for the final optimization. For TNNR-ADMMAP, we make use of an adaptive penalty according to a novel update rule for ADMM to achieve a faster convergence rate. Our empirical study shows encouraging results of the proposed algorithms in comparison to the state-of-the-art matrix completion algorithms on both synthetic and real visual datasets.

  4. A blind deconvolution method based on L1/L2 regularization prior in the gradient space

    NASA Astrophysics Data System (ADS)

    Cai, Ying; Shi, Yu; Hua, Xia

    2018-02-01

    In the process of image restoration, the result of image restoration is very different from the real image because of the existence of noise, in order to solve the ill posed problem in image restoration, a blind deconvolution method based on L1/L2 regularization prior to gradient domain is proposed. The method presented in this paper first adds a function to the prior knowledge, which is the ratio of the L1 norm to the L2 norm, and takes the function as the penalty term in the high frequency domain of the image. Then, the function is iteratively updated, and the iterative shrinkage threshold algorithm is applied to solve the high frequency image. In this paper, it is considered that the information in the gradient domain is better for the estimation of blur kernel, so the blur kernel is estimated in the gradient domain. This problem can be quickly implemented in the frequency domain by fast Fast Fourier Transform. In addition, in order to improve the effectiveness of the algorithm, we have added a multi-scale iterative optimization method. This paper proposes the blind deconvolution method based on L1/L2 regularization priors in the gradient space can obtain the unique and stable solution in the process of image restoration, which not only keeps the edges and details of the image, but also ensures the accuracy of the results.

  5. On the mass concentration of L^2-constrained minimizers for a class of Schrödinger-Poisson equations

    NASA Astrophysics Data System (ADS)

    Ye, Hongyu; Luo, Tingjian

    2018-06-01

    In this paper, we study the mass concentration behavior of positive solutions with prescribed L^2-norm for a class of Schrödinger-Poisson equations in R^3 -Δ u-μ u+φ _uu-|u|^{p-2}u=0, &{} x\\in R^3, μ \\in R, -Δ φ _u=|u|^2, where p\\in (2,6). We show that positive solutions with prescribed L^2-norm as which tends to 0 (in some cases) or to + ∞ (in others), behave like the positive solution of Schrödinger equation -Δ u+u=|u|^{p-2}u in R^3.

  6. Lp-Norm Regularization in Volumetric Imaging of Cardiac Current Sources

    PubMed Central

    Rahimi, Azar; Xu, Jingjia; Wang, Linwei

    2013-01-01

    Advances in computer vision have substantially improved our ability to analyze the structure and mechanics of the heart. In comparison, our ability to observe and analyze cardiac electrical activities is much limited. The progress to computationally reconstruct cardiac current sources from noninvasive voltage data sensed on the body surface has been hindered by the ill-posedness and the lack of a unique solution of the reconstruction problem. Common L2- and L1-norm regularizations tend to produce a solution that is either too diffused or too scattered to reflect the complex spatial structure of current source distribution in the heart. In this work, we propose a general regularization with Lp-norm (1 < p < 2) constraint to bridge the gap and balance between an overly smeared and overly focal solution in cardiac source reconstruction. In a set of phantom experiments, we demonstrate the superiority of the proposed Lp-norm method over its L1 and L2 counterparts in imaging cardiac current sources with increasing extents. Through computer-simulated and real-data experiments, we further demonstrate the feasibility of the proposed method in imaging the complex structure of excitation wavefront, as well as current sources distributed along the postinfarction scar border. This ability to preserve the spatial structure of source distribution is important for revealing the potential disruption to the normal heart excitation. PMID:24348735

  7. Smooth Approximation l 0-Norm Constrained Affine Projection Algorithm and Its Applications in Sparse Channel Estimation

    PubMed Central

    2014-01-01

    We propose a smooth approximation l 0-norm constrained affine projection algorithm (SL0-APA) to improve the convergence speed and the steady-state error of affine projection algorithm (APA) for sparse channel estimation. The proposed algorithm ensures improved performance in terms of the convergence speed and the steady-state error via the combination of a smooth approximation l 0-norm (SL0) penalty on the coefficients into the standard APA cost function, which gives rise to a zero attractor that promotes the sparsity of the channel taps in the channel estimation and hence accelerates the convergence speed and reduces the steady-state error when the channel is sparse. The simulation results demonstrate that our proposed SL0-APA is superior to the standard APA and its sparsity-aware algorithms in terms of both the convergence speed and the steady-state behavior in a designated sparse channel. Furthermore, SL0-APA is shown to have smaller steady-state error than the previously proposed sparsity-aware algorithms when the number of nonzero taps in the sparse channel increases. PMID:24790588

  8. EEG minimum-norm estimation compared with MEG dipole fitting in the localization of somatosensory sources at S1.

    PubMed

    Komssi, S; Huttunen, J; Aronen, H J; Ilmoniemi, R J

    2004-03-01

    Dipole models, which are frequently used in attempts to solve the electromagnetic inverse problem, require explicit a priori assumptions about the cerebral current sources. This is not the case for solutions based on minimum-norm estimates. In the present study, we evaluated the spatial accuracy of the L2 minimum-norm estimate (MNE) in realistic noise conditions by assessing its ability to localize sources of evoked responses at the primary somatosensory cortex (SI). Multichannel somatosensory evoked potentials (SEPs) and magnetic fields (SEFs) were recorded in 5 subjects while stimulating the median and ulnar nerves at the left wrist. A Tikhonov-regularized L2-MNE, constructed on a spherical surface from the SEP signals, was compared with an equivalent current dipole (ECD) solution obtained from the SEFs. Primarily tangential current sources accounted for both SEP and SEF distributions at around 20 ms (N20/N20m) and 70 ms (P70/P70m), which deflections were chosen for comparative analysis. The distances between the locations of the maximum current densities obtained from MNE and the locations of ECDs were on the average 12-13 mm for both deflections and nerves stimulated. In accordance with the somatotopical order of SI, both the MNE and ECD tended to localize median nerve activation more laterally than ulnar nerve activation for the N20/N20m deflection. Simulation experiments further indicated that, with a proper estimate of the source depth and with a good fit of the head model, the MNE can reach a mean accuracy of 5 mm in 0.2-microV root-mean-square noise. When compared with previously reported localizations based on dipole modelling of SEPs, it appears that equally accurate localization of S1 can be obtained with the MNE. MNE can be used to verify parametric source modelling results. Having a relatively good localization accuracy and requiring minimal assumptions, the MNE may be useful for the localization of poorly known activity distributions and for tracking

  9. System identification using Nuclear Norm & Tabu Search optimization

    NASA Astrophysics Data System (ADS)

    Ahmed, Asif A.; Schoen, Marco P.; Bosworth, Ken W.

    2018-01-01

    In recent years, subspace System Identification (SI) algorithms have seen increased research, stemming from advanced minimization methods being applied to the Nuclear Norm (NN) approach in system identification. These minimization algorithms are based on hard computing methodologies. To the authors’ knowledge, as of now, there has been no work reported that utilizes soft computing algorithms to address the minimization problem within the nuclear norm SI framework. A linear, time-invariant, discrete time system is used in this work as the basic model for characterizing a dynamical system to be identified. The main objective is to extract a mathematical model from collected experimental input-output data. Hankel matrices are constructed from experimental data, and the extended observability matrix is employed to define an estimated output of the system. This estimated output and the actual - measured - output are utilized to construct a minimization problem. An embedded rank measure assures minimum state realization outcomes. Current NN-SI algorithms employ hard computing algorithms for minimization. In this work, we propose a simple Tabu Search (TS) algorithm for minimization. TS algorithm based SI is compared with the iterative Alternating Direction Method of Multipliers (ADMM) line search optimization based NN-SI. For comparison, several different benchmark system identification problems are solved by both approaches. Results show improved performance of the proposed SI-TS algorithm compared to the NN-SI ADMM algorithm.

  10. Neutrino masses in the minimal gauged (B -L ) supersymmetry

    NASA Astrophysics Data System (ADS)

    Yan, Yu-Li; Feng, Tai-Fu; Yang, Jin-Lei; Zhang, Hai-Bin; Zhao, Shu-Min; Zhu, Rong-Fei

    2018-03-01

    We present the radiative corrections to neutrino masses in a minimal supersymmetric extension of the standard model with local U (1 )B -L symmetry. At tree level, three tiny active neutrinos and two nearly massless sterile neutrinos can be obtained through the seesaw mechanism. Considering the one-loop corrections to the neutrino masses, the numerical results indicate that two sterile neutrinos obtain KeV masses and the small active-sterile neutrino mixing angles. The lighter sterile neutrino is a very interesting dark matter candidate in cosmology. Meanwhile, the active neutrinos mixing angles and mass squared differences agree with present experimental data.

  11. Autoregressive model in the Lp norm space for EEG analysis.

    PubMed

    Li, Peiyang; Wang, Xurui; Li, Fali; Zhang, Rui; Ma, Teng; Peng, Yueheng; Lei, Xu; Tian, Yin; Guo, Daqing; Liu, Tiejun; Yao, Dezhong; Xu, Peng

    2015-01-30

    The autoregressive (AR) model is widely used in electroencephalogram (EEG) analyses such as waveform fitting, spectrum estimation, and system identification. In real applications, EEGs are inevitably contaminated with unexpected outlier artifacts, and this must be overcome. However, most of the current AR models are based on the L2 norm structure, which exaggerates the outlier effect due to the square property of the L2 norm. In this paper, a novel AR object function is constructed in the Lp (p≤1) norm space with the aim to compress the outlier effects on EEG analysis, and a fast iteration procedure is developed to solve this new AR model. The quantitative evaluation using simulated EEGs with outliers proves that the proposed Lp (p≤1) AR can estimate the AR parameters more robustly than the Yule-Walker, Burg and LS methods, under various simulated outlier conditions. The actual application to the resting EEG recording with ocular artifacts also demonstrates that Lp (p≤1) AR can effectively address the outliers and recover a resting EEG power spectrum that is more consistent with its physiological basis. Copyright © 2014 Elsevier B.V. All rights reserved.

  12. Contests versus Norms: Implications of Contest-Based and Norm-Based Intervention Techniques

    PubMed Central

    Bergquist, Magnus; Nilsson, Andreas; Hansla, André

    2017-01-01

    Interventions using either contests or norms can promote environmental behavioral change. Yet research on the implications of contest-based and norm-based interventions is lacking. Based on Goal-framing theory, we suggest that a contest-based intervention frames a gain goal promoting intensive but instrumental behavioral engagement. In contrast, the norm-based intervention was expected to frame a normative goal activating normative obligations for targeted and non-targeted behavior and motivation to engage in pro-environmental behaviors in the future. In two studies participants (n = 347) were randomly assigned to either a contest- or a norm-based intervention technique. Participants in the contest showed more intensive engagement in both studies. Participants in the norm-based intervention tended to report higher intentions for future energy conservation (Study 1) and higher personal norms for non-targeted pro-environmental behaviors (Study 2). These findings suggest that contest-based intervention technique frames a gain goal, while norm-based intervention frames a normative goal. PMID:29218026

  13. Contests versus Norms: Implications of Contest-Based and Norm-Based Intervention Techniques.

    PubMed

    Bergquist, Magnus; Nilsson, Andreas; Hansla, André

    2017-01-01

    Interventions using either contests or norms can promote environmental behavioral change. Yet research on the implications of contest-based and norm-based interventions is lacking. Based on Goal-framing theory, we suggest that a contest-based intervention frames a gain goal promoting intensive but instrumental behavioral engagement. In contrast, the norm-based intervention was expected to frame a normative goal activating normative obligations for targeted and non-targeted behavior and motivation to engage in pro-environmental behaviors in the future. In two studies participants ( n = 347) were randomly assigned to either a contest- or a norm-based intervention technique. Participants in the contest showed more intensive engagement in both studies. Participants in the norm-based intervention tended to report higher intentions for future energy conservation (Study 1) and higher personal norms for non-targeted pro-environmental behaviors (Study 2). These findings suggest that contest-based intervention technique frames a gain goal, while norm-based intervention frames a normative goal.

  14. Nuclear norm-based 2-DPCA for extracting features from images.

    PubMed

    Zhang, Fanlong; Yang, Jian; Qian, Jianjun; Xu, Yong

    2015-10-01

    The 2-D principal component analysis (2-DPCA) is a widely used method for image feature extraction. However, it can be equivalently implemented via image-row-based principal component analysis. This paper presents a structured 2-D method called nuclear norm-based 2-DPCA (N-2-DPCA), which uses a nuclear norm-based reconstruction error criterion. The nuclear norm is a matrix norm, which can provide a structured 2-D characterization for the reconstruction error image. The reconstruction error criterion is minimized by converting the nuclear norm-based optimization problem into a series of F-norm-based optimization problems. In addition, N-2-DPCA is extended to a bilateral projection-based N-2-DPCA (N-B2-DPCA). The virtue of N-B2-DPCA over N-2-DPCA is that an image can be represented with fewer coefficients. N-2-DPCA and N-B2-DPCA are applied to face recognition and reconstruction and evaluated using the Extended Yale B, CMU PIE, FRGC, and AR databases. Experimental results demonstrate the effectiveness of the proposed methods.

  15. Resource Balancing Control Allocation

    NASA Technical Reports Server (NTRS)

    Frost, Susan A.; Bodson, Marc

    2010-01-01

    Next generation aircraft with a large number of actuators will require advanced control allocation methods to compute the actuator commands needed to follow desired trajectories while respecting system constraints. Previously, algorithms were proposed to minimize the l1 or l2 norms of the tracking error and of the control effort. The paper discusses the alternative choice of using the l1 norm for minimization of the tracking error and a normalized l(infinity) norm, or sup norm, for minimization of the control effort. The algorithm computes the norm of the actuator deflections scaled by the actuator limits. Minimization of the control effort then translates into the minimization of the maximum actuator deflection as a percentage of its range of motion. The paper shows how the problem can be solved effectively by converting it into a linear program and solving it using a simplex algorithm. Properties of the algorithm are investigated through examples. In particular, the min-max criterion results in a type of resource balancing, where the resources are the control surfaces and the algorithm balances these resources to achieve the desired command. A study of the sensitivity of the algorithms to the data is presented, which shows that the normalized l(infinity) algorithm has the lowest sensitivity, although high sensitivities are observed whenever the limits of performance are reached.

  16. A new adaptive L1-norm for optimal descriptor selection of high-dimensional QSAR classification model for anti-hepatitis C virus activity of thiourea derivatives.

    PubMed

    Algamal, Z Y; Lee, M H

    2017-01-01

    A high-dimensional quantitative structure-activity relationship (QSAR) classification model typically contains a large number of irrelevant and redundant descriptors. In this paper, a new design of descriptor selection for the QSAR classification model estimation method is proposed by adding a new weight inside L1-norm. The experimental results of classifying the anti-hepatitis C virus activity of thiourea derivatives demonstrate that the proposed descriptor selection method in the QSAR classification model performs effectively and competitively compared with other existing penalized methods in terms of classification performance on both the training and the testing datasets. Moreover, it is noteworthy that the results obtained in terms of stability test and applicability domain provide a robust QSAR classification model. It is evident from the results that the developed QSAR classification model could conceivably be employed for further high-dimensional QSAR classification studies.

  17. From Norm Adoption to Norm Internalization

    NASA Astrophysics Data System (ADS)

    Conte, Rosaria; Andrighetto, Giulia; Villatoro, Daniel

    In this presentation, advances in modeling the mental dynamics of norms will be presented. In particular, the process from norm-adoption, possibly yielding new normative goals, to different forms of norm compliance will be focused upon, including norm internalization, which is at study in social-behavioral sciences and moral philosophy since long. Of late, the debate was revamped within the rationality approach pointing to the role of norm internalization as a less costly and more reliable enforcement system than social control. So far, poor attention was paid to the mental underpinnings of internalization. In this presentation, a rich cognitive model of different types, degrees and factors of internalization is shown. The initial implementation of this model on EMIL-A, a normative agent architecture developed and applied to the.

  18. Improved dynamic MRI reconstruction by exploiting sparsity and rank-deficiency.

    PubMed

    Majumdar, Angshul

    2013-06-01

    In this paper we address the problem of dynamic MRI reconstruction from partially sampled K-space data. Our work is motivated by previous studies in this area that proposed exploiting the spatiotemporal correlation of the dynamic MRI sequence by posing the reconstruction problem as a least squares minimization regularized by sparsity and low-rank penalties. Ideally the sparsity and low-rank penalties should be represented by the l(0)-norm and the rank of a matrix; however both are NP hard penalties. The previous studies used the convex l(1)-norm as a surrogate for the l(0)-norm and the non-convex Schatten-q norm (01) as a surrogate for the rank of matrix. Following past research in sparse recovery, we know that non-convex l(p)-norm (0

    1) is a better substitute for the NP hard l(0)-norm than the convex l(1)-norm. Motivated by these studies, we propose improvements over the previous studies by replacing the l(1)-norm sparsity penalty by the lp-norm. Thus, we reconstruct the dynamic MRI sequence by solving a least squares minimization problem regularized by l(p)-norm as the sparsity penalty and Schatten-q norm as the low-rank penalty. There are no efficient algorithms to solve the said problems. In this paper, we derive efficient algorithms to solve them. The experiments have been carried out on Dynamic Contrast Enhanced (DCE) MRI datasets. Both quantitative and qualitative analysis indicates the superiority of our proposed improvement over the existing methods. Copyright © 2013 Elsevier Inc. All rights reserved.

  19. A comparative study of minimum norm inverse methods for MEG imaging

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Leahy, R.M.; Mosher, J.C.; Phillips, J.W.

    1996-07-01

    The majority of MEG imaging techniques currently in use fall into the general class of (weighted) minimum norm methods. The minimization of a norm is used as the basis for choosing one from a generally infinite set of solutions that provide an equally good fit to the data. This ambiguity in the solution arises from the inherent non- uniqueness of the continuous inverse problem and is compounded by the imbalance between the relatively small number of measurements and the large number of source voxels. Here we present a unified view of the minimum norm methods and describe how we canmore » use Tikhonov regularization to avoid instabilities in the solutions due to noise. We then compare the performance of regularized versions of three well known linear minimum norm methods with the non-linear iteratively reweighted minimum norm method and a Bayesian approach.« less

  20. Group Norms, Threat, and Children's Racial Prejudice

    ERIC Educational Resources Information Center

    Nesdale, Drew; Maass, Anne; Durkin, Kevin; Griffiths, Judith

    2005-01-01

    To assess predictions from social identity development theory (SIDT; Nesdale, 2004) concerning children's ethnic/racial prejudice, 197 Anglo-Australian children ages 7 or 9 years participated in a minimal group study as a member of a team that had a norm of inclusion or exclusion. The team was threatened or not threatened by an out-group that was…

  1. Health-related quality of life measured using the EQ-5D-5L: South Australian population norms.

    PubMed

    McCaffrey, Nikki; Kaambwa, Billingsley; Currow, David C; Ratcliffe, Julie

    2016-09-20

    Although a five level version of the widely-used EuroQol 5 dimensions (EQ-5D) instrument has been developed, population norms are not yet available for Australia to inform the future valuation of health in economic evaluations. The aim of this study was to estimate HrQOL normative values for the EQ-5D-5L preference-based measure in a large, randomly selected, community sample in South Australia. The EQ-5D-5L instrument was included in the 2013 South Australian Health Omnibus Survey, an interviewer-administered, face-to-face, cross-sectional survey. Respondents rated their level of impairment across dimensions (mobility, self-care, usual activities, pain/discomfort, and anxiety/depression) and global health rating on a visual analogue scale (EQ-VAS). Utility scores were derived using the newly-developed UK general population-based algorithm and relationships between utility and EQ-VAS scores and socio-demographic factors were also explored using multivariate regression analyses. Ultimately, 2,908 adults participated in the survey (63.4 % participation rate). The mean utility and EQ-VAS scores were 0.91 (95 CI 0.90, 0.91) and 78.55 (95 % CI 77.95, 79.15), respectively. Almost half of respondents reported no problems across all dimensions (42.8 %), whereas only 7.2 % rated their health >90 on the EQ-VAS (100 = the best health you can imagine). Younger age, male gender, longer duration of education, higher annual household income, employment and marriage/de facto relationships were all independent, statistically significant predictors of better health status (p < 0.01) measured with the EQ-VAS. Only age and employment status were associated with higher utility scores, indicating fundamental differences between these measures of health status. This is the first Australian study to apply the EQ-5D-5L in a large, community sample. Overall, findings are consistent with EQ-5D-5L utility and VAS scores reported for other countries and indicate that the majority

  2. The Role of Perceived Injunctive Alcohol Norms in Adolescent Drinking Behavior

    PubMed Central

    Pedersen, Eric R.; Osilla, Karen Chan; Miles, Jeremy N.V.; Tucker, Joan S.; Ewing, Brett A.; Shih, Regina A.; D’Amico, Elizabeth J.

    2016-01-01

    Peers have a major influence on youth during adolescence, and perceptions about peer alcohol use (perceived norms) are often associated with personal drinking behavior among youth. Most of the research on perceived norms among adolescents focuses on perceived descriptive norms only, or perceptions about peers’ behavior, and correcting these perceptions are a major focus of many prevention programs with adolescents. In contrast, perceived injunctive norms, which are personal perceptions about peers’ attitudes regarding the acceptability of behaviors, have been minimally examined in the adolescent drinking literature. Yet correcting perceptions about these perceived peer attitudes may be an important component to include in prevention programs with youth. Using a sample of 2,493 high school-aged youth (mean age = 17.3), we assessed drinking behavior (past year use; past month frequency, quantity, and peak drinks), drinking consequences, and perceived descriptive and injunctive norms to examine the relationships of perceived injunctive and descriptive norms on adolescent drinking behavior. Findings indicated that although perceived descriptive norms were associated with some drinking outcomes (past year use; past month frequency; past month quantity; peak drinks), perceived injunctive norms were associated with all drinking outcomes, including outcomes of consequences, even after controlling for perceived descriptive norms. Findings suggest that consideration of perceived injunctive norms may be important in models of adolescent drinking. Prevention programs that do not include injunctive norms feedback may miss an important opportunity to enhance effectiveness of such prevention programs targeting adolescent alcohol use. PMID:27978424

  3. OPERATOR NORM INEQUALITIES BETWEEN TENSOR UNFOLDINGS ON THE PARTITION LATTICE.

    PubMed

    Wang, Miaoyan; Duc, Khanh Dao; Fischer, Jonathan; Song, Yun S

    2017-05-01

    Interest in higher-order tensors has recently surged in data-intensive fields, with a wide range of applications including image processing, blind source separation, community detection, and feature extraction. A common paradigm in tensor-related algorithms advocates unfolding (or flattening) the tensor into a matrix and applying classical methods developed for matrices. Despite the popularity of such techniques, how the functional properties of a tensor changes upon unfolding is currently not well understood. In contrast to the body of existing work which has focused almost exclusively on matricizations, we here consider all possible unfoldings of an order- k tensor, which are in one-to-one correspondence with the set of partitions of {1, …, k }. We derive general inequalities between the l p -norms of arbitrary unfoldings defined on the partition lattice. In particular, we demonstrate how the spectral norm ( p = 2) of a tensor is bounded by that of its unfoldings, and obtain an improved upper bound on the ratio of the Frobenius norm to the spectral norm of an arbitrary tensor. For specially-structured tensors satisfying a generalized definition of orthogonal decomposability, we prove that the spectral norm remains invariant under specific subsets of unfolding operations.

  4. Generalizations of Tikhonov's regularized method of least squares to non-Euclidean vector norms

    NASA Astrophysics Data System (ADS)

    Volkov, V. V.; Erokhin, V. I.; Kakaev, V. V.; Onufrei, A. Yu.

    2017-09-01

    Tikhonov's regularized method of least squares and its generalizations to non-Euclidean norms, including polyhedral, are considered. The regularized method of least squares is reduced to mathematical programming problems obtained by "instrumental" generalizations of the Tikhonov lemma on the minimal (in a certain norm) solution of a system of linear algebraic equations with respect to an unknown matrix. Further studies are needed for problems concerning the development of methods and algorithms for solving reduced mathematical programming problems in which the objective functions and admissible domains are constructed using polyhedral vector norms.

  5. Vector-valued Lizorkin-Triebel spaces and sharp trace theory for functions in Sobolev spaces with mixed \\pmb{L_p}-norm for parabolic problems

    NASA Astrophysics Data System (ADS)

    Weidemaier, P.

    2005-06-01

    The trace problem on the hypersurface y_n=0 is investigated for a function u=u(y,t) \\in L_q(0,T;W_{\\underline p}^{\\underline m}(\\mathbb R_+^n)) with \\partial_t u \\in L_q(0,T; L_{\\underline p}(\\mathbb R_+^n)), that is, Sobolev spaces with mixed Lebesgue norm L_{\\underline p,q}(\\mathbb R^n_+\\times(0,T))=L_q(0,T;L_{\\underline p}(\\mathbb R_+^n)) are considered; here \\underline p=(p_1,\\dots,p_n) is a vector and \\mathbb R^n_+=\\mathbb R^{n-1} \\times (0,\\infty). Such function spaces are useful in the context of parabolic equations. They allow, in particular, different exponents of summability in space and time. It is shown that the sharp regularity of the trace in the time variable is characterized by the Lizorkin-Triebel space F_{q,p_n}^{1-1/(p_nm_n)}(0,T;L_{\\widetilde{\\underline p}}(\\mathbb R^{n-1})), \\underline p=(\\widetilde{\\underline p},p_n). A similar result is established for first order spatial derivatives of u. These results allow one to determine the exact spaces for the data in the inhomogeneous Dirichlet and Neumann problems for parabolic equations of the second order if the solution is in the space L_q(0,T; W_p^2(\\Omega)) \\cap W_q^1(0,T;L_p(\\Omega)) with p \\le q.

  6. (L)-Valine production with minimization of by-products' synthesis in Corynebacterium glutamicum and Brevibacterium flavum.

    PubMed

    Hou, Xiaohu; Chen, Xinde; Zhang, Yue; Qian, He; Zhang, Weiguo

    2012-12-01

    Corynebacterium glutamicum ATCC13032 and Brevibacterium flavum JV16 were engineered for L-valine production by over-expressing ilvEBN ( r ) C genes at 31 °C in 72 h fermentation. Different strategies were carried out to reduce the by-products' accumulation in L-valine fermentation and also to increase the availability of precursor for L-valine biosynthesis. The native promoter of ilvA of C. glutamicum was replaced with a weak promoter MPilvA (P-ilvAM1CG) to reduce the biosynthetic rate of L-isoleucine. Effect of different relative dissolved oxygen on L-valine production and by-products' formation was recorded, indicating that 15 % saturation may be the most appropriate relative dissolved oxygen for L-valine fermentation with almost no L-lactic acid and L-glutamate formed. To minimize L-alanine accumulation, alaT and/or avtA was inactivated in C. glutamicum and B. flavum, respectively. Compared to high concentration of L-alanine accumulated by alaT inactivated strains harboring ilvEBN ( r ) C genes, L-alanine concentration was reduced to 0.18 g/L by C. glutamicum ATCC13032MPilvA△avtA pDXW-8-ilvEBN ( r ) C, and 0.22 g/L by B. flavum JV16avtA::Cm pDXW-8-ilvEBN ( r ) C. Meanwhile, L-valine production and conversion efficiency were enhanced to 31.15 g/L and 0.173 g/g by C. glutamicum ATCC13032MPilvA△avtA pDXW-8-ilvEBN ( r ) C, 38.82 g/L and 0.252 g/g by B. flavum JV16avtA::Cm pDXW-8-ilvEBN ( r ) C. This study provides combined strategies to improve L-valine yield by minimization of by-products' production.

  7. Reconstructing Norms

    ERIC Educational Resources Information Center

    Gorgorio, Nuria; Planas, Nuria

    2005-01-01

    Starting from the constructs "cultural scripts" and "social representations", and on the basis of the empirical research we have been developing until now, we revisit the construct norms from a sociocultural perspective. Norms, both sociomathematical norms and norms of the mathematical practice, as cultural scripts influenced…

  8. A norm knockout method on indirect reciprocity to reveal indispensable norms

    NASA Astrophysics Data System (ADS)

    Yamamoto, Hitoshi; Okada, Isamu; Uchida, Satoshi; Sasaki, Tatsuya

    2017-03-01

    Although various norms for reciprocity-based cooperation have been suggested that are evolutionarily stable against invasion from free riders, the process of alternation of norms and the role of diversified norms remain unclear in the evolution of cooperation. We clarify the co-evolutionary dynamics of norms and cooperation in indirect reciprocity and also identify the indispensable norms for the evolution of cooperation. Inspired by the gene knockout method, a genetic engineering technique, we developed the norm knockout method and clarified the norms necessary for the establishment of cooperation. The results of numerical investigations revealed that the majority of norms gradually transitioned to tolerant norms after defectors are eliminated by strict norms. Furthermore, no cooperation emerges when specific norms that are intolerant to defectors are knocked out.

  9. The importance of being fractional in mixing: optimal choice of the index s in H-s norm

    NASA Astrophysics Data System (ADS)

    Vermach, Lukas; Caulfield, C. P.

    2015-11-01

    A natural measure of homogeneity of a mixture is the variance of the concentration field, which in the case of a zero-mean field is the L2-norm. Mathew et al. (Physica D, 2005) introduced a new multi-scale measure to quantify mixing referred to as the mix-norm, which is equivalent to the H - 1 / 2 norm, the Sobolev norm of negative fractional index. Unlike the L2-norm, the mix-norm is not conserved by the advection equation and thus captures mixing even in the non-diffusive systems. Furthermore, the mix-norm is consistent with the ergodic definition of mixing and Lin et al. (JFM, 2011) showed that this property extends to any norm from the class H-s , s > 0 . We consider a zero-mean passive scalar field organised into two layers of different concentrations advected by a flow field in a torus. We solve two non-linear optimisation problems. We identify the optimal initial perturbation of the velocity field with given initial energy as well as the optimal forcing with given total action (the time integral of the kinetic energy of the flow) which both yield maximal mixing by a target time horizon. We analyse sensitivity of the results with respect to s-variation and thus address the importance of the choice of the fractional index This work was supported by the UK Engineering and Physical Sciences Research Council (EPSRC) grant EP/H023348/1 for the University of Cambridge Centre for Doctoral Training, the Cambridge Centre for Analysis.

  10. A norm knockout method on indirect reciprocity to reveal indispensable norms

    PubMed Central

    Yamamoto, Hitoshi; Okada, Isamu; Uchida, Satoshi; Sasaki, Tatsuya

    2017-01-01

    Although various norms for reciprocity-based cooperation have been suggested that are evolutionarily stable against invasion from free riders, the process of alternation of norms and the role of diversified norms remain unclear in the evolution of cooperation. We clarify the co-evolutionary dynamics of norms and cooperation in indirect reciprocity and also identify the indispensable norms for the evolution of cooperation. Inspired by the gene knockout method, a genetic engineering technique, we developed the norm knockout method and clarified the norms necessary for the establishment of cooperation. The results of numerical investigations revealed that the majority of norms gradually transitioned to tolerant norms after defectors are eliminated by strict norms. Furthermore, no cooperation emerges when specific norms that are intolerant to defectors are knocked out. PMID:28276485

  11. Improved sparse decomposition based on a smoothed L0 norm using a Laplacian kernel to select features from fMRI data.

    PubMed

    Zhang, Chuncheng; Song, Sutao; Wen, Xiaotong; Yao, Li; Long, Zhiying

    2015-04-30

    Feature selection plays an important role in improving the classification accuracy of multivariate classification techniques in the context of fMRI-based decoding due to the "few samples and large features" nature of functional magnetic resonance imaging (fMRI) data. Recently, several sparse representation methods have been applied to the voxel selection of fMRI data. Despite the low computational efficiency of the sparse representation methods, they still displayed promise for applications that select features from fMRI data. In this study, we proposed the Laplacian smoothed L0 norm (LSL0) approach for feature selection of fMRI data. Based on the fast sparse decomposition using smoothed L0 norm (SL0) (Mohimani, 2007), the LSL0 method used the Laplacian function to approximate the L0 norm of sources. Results of the simulated and real fMRI data demonstrated the feasibility and robustness of LSL0 for the sparse source estimation and feature selection. Simulated results indicated that LSL0 produced more accurate source estimation than SL0 at high noise levels. The classification accuracy using voxels that were selected by LSL0 was higher than that by SL0 in both simulated and real fMRI experiment. Moreover, both LSL0 and SL0 showed higher classification accuracy and required less time than ICA and t-test for the fMRI decoding. LSL0 outperformed SL0 in sparse source estimation at high noise level and in feature selection. Moreover, LSL0 and SL0 showed better performance than ICA and t-test for feature selection. Copyright © 2015 Elsevier B.V. All rights reserved.

  12. Control Allocation with Load Balancing

    NASA Technical Reports Server (NTRS)

    Bodson, Marc; Frost, Susan A.

    2009-01-01

    Next generation aircraft with a large number of actuators will require advanced control allocation methods to compute the actuator commands needed to follow desired trajectories while respecting system constraints. Previously, algorithms were proposed to minimize the l1 or l2 norms of the tracking error and of the actuator deflections. The paper discusses the alternative choice of the l(infinity) norm, or sup norm. Minimization of the control effort translates into the minimization of the maximum actuator deflection (min-max optimization). The paper shows how the problem can be solved effectively by converting it into a linear program and solving it using a simplex algorithm. Properties of the algorithm are also investigated through examples. In particular, the min-max criterion results in a type of load balancing, where the load is th desired command and the algorithm balances this load among various actuators. The solution using the l(infinity) norm also results in better robustness to failures and to lower sensitivity to nonlinearities in illustrative examples.

  13. Weighted low-rank sparse model via nuclear norm minimization for bearing fault detection

    NASA Astrophysics Data System (ADS)

    Du, Zhaohui; Chen, Xuefeng; Zhang, Han; Yang, Boyuan; Zhai, Zhi; Yan, Ruqiang

    2017-07-01

    It is a fundamental task in the machine fault diagnosis community to detect impulsive signatures generated by the localized faults of bearings. The main goal of this paper is to exploit the low-rank physical structure of periodic impulsive features and further establish a weighted low-rank sparse model for bearing fault detection. The proposed model mainly consists of three basic components: an adaptive partition window, a nuclear norm regularization and a weighted sequence. Firstly, due to the periodic repetition mechanism of impulsive feature, an adaptive partition window could be designed to transform the impulsive feature into a data matrix. The highlight of partition window is to accumulate all local feature information and align them. Then, all columns of the data matrix share similar waveforms and a core physical phenomenon arises, i.e., these singular values of the data matrix demonstrates a sparse distribution pattern. Therefore, a nuclear norm regularization is enforced to capture that sparse prior. However, the nuclear norm regularization treats all singular values equally and thus ignores one basic fact that larger singular values have more information volume of impulsive features and should be preserved as much as possible. Therefore, a weighted sequence with adaptively tuning weights inversely proportional to singular amplitude is adopted to guarantee the distribution consistence of large singular values. On the other hand, the proposed model is difficult to solve due to its non-convexity and thus a new algorithm is developed to search one satisfying stationary solution through alternatively implementing one proximal operator operation and least-square fitting. Moreover, the sensitivity analysis and selection principles of algorithmic parameters are comprehensively investigated through a set of numerical experiments, which shows that the proposed method is robust and only has a few adjustable parameters. Lastly, the proposed model is applied to the

  14. Hessian-based norm regularization for image restoration with biomedical applications.

    PubMed

    Lefkimmiatis, Stamatios; Bourquard, Aurélien; Unser, Michael

    2012-03-01

    We present nonquadratic Hessian-based regularization methods that can be effectively used for image restoration problems in a variational framework. Motivated by the great success of the total-variation (TV) functional, we extend it to also include second-order differential operators. Specifically, we derive second-order regularizers that involve matrix norms of the Hessian operator. The definition of these functionals is based on an alternative interpretation of TV that relies on mixed norms of directional derivatives. We show that the resulting regularizers retain some of the most favorable properties of TV, i.e., convexity, homogeneity, rotation, and translation invariance, while dealing effectively with the staircase effect. We further develop an efficient minimization scheme for the corresponding objective functions. The proposed algorithm is of the iteratively reweighted least-square type and results from a majorization-minimization approach. It relies on a problem-specific preconditioned conjugate gradient method, which makes the overall minimization scheme very attractive since it can be applied effectively to large images in a reasonable computational time. We validate the overall proposed regularization framework through deblurring experiments under additive Gaussian noise on standard and biomedical images.

  15. English Language Learners' Nonword Repetition Performance: The Influence of Age, L2 Vocabulary Size, Length of L2 Exposure, and L1 Phonology.

    PubMed

    Duncan, Tamara Sorenson; Paradis, Johanne

    2016-02-01

    This study examined individual differences in English language learners' (ELLs) nonword repetition (NWR) accuracy, focusing on the effects of age, English vocabulary size, length of exposure to English, and first-language (L1) phonology. Participants were 75 typically developing ELLs (mean age 5;8 [years;months]) whose exposure to English began on average at age 4;4. Children spoke either a Chinese language or South Asian language as an L1 and were given English standardized tests for NWR and receptive vocabulary. Although the majority of ELLs scored within or above the monolingual normal range (71%), 29% scored below. Mixed logistic regression modeling revealed that a larger English vocabulary, longer English exposure, South Asian L1, and older age all had significant and positive effects on ELLs' NWR accuracy. Error analyses revealed the following L1 effect: onset consonants were produced more accurately than codas overall, but this effect was stronger for the Chinese group whose L1s have a more limited coda inventory compared with English. ELLs' NWR performance is influenced by a number of factors. Consideration of these factors is important in deciding whether monolingual norm referencing is appropriate for ELL children.

  16. Variational method based on Retinex with double-norm hybrid constraints for uneven illumination correction

    NASA Astrophysics Data System (ADS)

    Li, Shuo; Wang, Hui; Wang, Liyong; Yu, Xiangzhou; Yang, Le

    2018-01-01

    The uneven illumination phenomenon reduces the quality of remote sensing image and causes interference in the subsequent processing and applications. A variational method based on Retinex with double-norm hybrid constraints for uneven illumination correction is proposed. The L1 norm and the L2 norm are adopted to constrain the textures and details of reflectance image and the smoothness of the illumination image, respectively. The problem of separating the illumination image from the reflectance image is transformed into the optimal solution of the variational model. In order to accelerate the solution, the split Bregman method is used to decompose the variational model into three subproblems, which are calculated by alternate iteration. Two groups of experiments are implemented on two synthetic images and three real remote sensing images. Compared with the variational Retinex method with single-norm constraint and the Mask method, the proposed method performs better in both visual evaluation and quantitative measurements. The proposed method can effectively eliminate the uneven illumination while maintaining the textures and details of the remote sensing image. Moreover, the proposed method using split Bregman method is more than 10 times faster than the method with the steepest descent method.

  17. Analysis of programming properties and the row-column generation method for 1-norm support vector machines.

    PubMed

    Zhang, Li; Zhou, WeiDa

    2013-12-01

    This paper deals with fast methods for training a 1-norm support vector machine (SVM). First, we define a specific class of linear programming with many sparse constraints, i.e., row-column sparse constraint linear programming (RCSC-LP). In nature, the 1-norm SVM is a sort of RCSC-LP. In order to construct subproblems for RCSC-LP and solve them, a family of row-column generation (RCG) methods is introduced. RCG methods belong to a category of decomposition techniques, and perform row and column generations in a parallel fashion. Specially, for the 1-norm SVM, the maximum size of subproblems of RCG is identical with the number of Support Vectors (SVs). We also introduce a semi-deleting rule for RCG methods and prove the convergence of RCG methods when using the semi-deleting rule. Experimental results on toy data and real-world datasets illustrate that it is efficient to use RCG to train the 1-norm SVM, especially in the case of small SVs. Copyright © 2013 Elsevier Ltd. All rights reserved.

  18. Support Minimized Inversion of Acoustic and Elastic Wave Scattering

    NASA Astrophysics Data System (ADS)

    Safaeinili, Ali

    Inversion of limited data is common in many areas of NDE such as X-ray Computed Tomography (CT), Ultrasonic and eddy current flaw characterization and imaging. In many applications, it is common to have a bias toward a solution with minimum (L^2)^2 norm without any physical justification. When it is a priori known that objects are compact as, say, with cracks and voids, by choosing "Minimum Support" functional instead of the minimum (L^2)^2 norm, an image can be obtained that is equally in agreement with the available data, while it is more consistent with what is most probably seen in the real world. We have utilized a minimum support functional to find a solution with the smallest volume. This inversion algorithm is most successful in reconstructing objects that are compact like voids and cracks. To verify this idea, we first performed a variational nonlinear inversion of acoustic backscatter data using minimum support objective function. A full nonlinear forward model was used to accurately study the effectiveness of the minimized support inversion without error due to the linear (Born) approximation. After successful inversions using a full nonlinear forward model, a linearized acoustic inversion was developed to increase speed and efficiency in imaging process. The results indicate that by using minimum support functional, we can accurately size and characterize voids and/or cracks which otherwise might be uncharacterizable. An extremely important feature of support minimized inversion is its ability to compensate for unknown absolute phase (zero-of-time). Zero-of-time ambiguity is a serious problem in the inversion of the pulse-echo data. The minimum support inversion was successfully used for the inversion of acoustic backscatter data due to compact scatterers without the knowledge of the zero-of-time. The main drawback to this type of inversion is its computer intensiveness. In order to make this type of constrained inversion available for common use, work

  19. Chinese translation norms for 1,429 English words.

    PubMed

    Wen, Yun; van Heuven, Walter J B

    2017-06-01

    We present Chinese translation norms for 1,429 English words. Chinese-English bilinguals (N = 28) were asked to provide the first Chinese translation that came to mind for 1,429 English words. The results revealed that 71 % of the English words received more than one correct translation indicating the large amount of translation ambiguity when translating from English to Chinese. The relationship between translation ambiguity and word frequency, concreteness and language proficiency was investigated. Although the significant correlations were not strong, results revealed that English word frequency was positively correlated with the number of alternative translations, whereas English word concreteness was negatively correlated with the number of translations. Importantly, regression analyses showed that the number of Chinese translations was predicted by word frequency and concreteness. Furthermore, an interaction between these predictors revealed that the number of translations was more affected by word frequency for more concrete words than for less concrete words. In addition, mixed-effects modelling showed that word frequency, concreteness and English language proficiency were all significant predictors of whether or not a dominant translation was provided. Finally, correlations between the word frequencies of English words and their Chinese dominant translations were higher for translation-unambiguous pairs than for translation-ambiguous pairs. The translation norms are made available in a database together with lexical information about the words, which will be a useful resource for researchers investigating Chinese-English bilingual language processing.

  20. Social Norms: Do We Love Norms Too Much?

    PubMed

    Bell, David C; Cox, Mary L

    2015-03-01

    Social norms are often cited as the cause of many social phenomena, especially as an explanation for prosocial family and relationship behaviors. And yet maybe we love the idea of social norms too much, as suggested by our failure to subject them to rigorous test. Compared to the detail in social norms theoretical orientations, there is very little detail in tests of normative theories. To provide guidance to researchers who invoke social norms as explanations, we catalog normative orientations that have been proposed to account for consistent patterns of action. We call on researchers to conduct tests of normative theories and the processes such theories assert.

  1. Social Norms: Do We Love Norms Too Much?

    PubMed Central

    Bell, David C.; Cox, Mary L.

    2014-01-01

    Social norms are often cited as the cause of many social phenomena, especially as an explanation for prosocial family and relationship behaviors. And yet maybe we love the idea of social norms too much, as suggested by our failure to subject them to rigorous test. Compared to the detail in social norms theoretical orientations, there is very little detail in tests of normative theories. To provide guidance to researchers who invoke social norms as explanations, we catalog normative orientations that have been proposed to account for consistent patterns of action. We call on researchers to conduct tests of normative theories and the processes such theories assert. PMID:25937833

  2. L-Serine overproduction with minimization of by-product synthesis by engineered Corynebacterium glutamicum.

    PubMed

    Zhu, Qinjian; Zhang, Xiaomei; Luo, Yuchang; Guo, Wen; Xu, Guoqiang; Shi, Jinsong; Xu, Zhenghong

    2015-02-01

    The direct fermentative production of L-serine by Corynebacterium glutamicum from sugars is attractive. However, superfluous by-product accumulation and low L-serine productivity limit its industrial production on large scale. This study aimed to investigate metabolic and bioprocess engineering strategies towards eliminating by-products as well as increasing L-serine productivity. Deletion of alaT and avtA encoding the transaminases and introduction of an attenuated mutant of acetohydroxyacid synthase (AHAS) increased both L-serine production level (26.23 g/L) and its productivity (0.27 g/L/h). Compared to the parent strain, the by-products L-alanine and L-valine accumulation in the resulting strain were reduced by 87 % (from 9.80 to 1.23 g/L) and 60 % (from 6.54 to 2.63 g/L), respectively. The modification decreased the metabolic flow towards the branched-chain amino acids (BCAAs) and induced to shift it towards L-serine production. Meanwhile, it was found that corn steep liquor (CSL) could stimulate cell growth and increase sucrose consumption rate as well as L-serine productivity. With addition of 2 g/L CSL, the resulting strain showed a significant improvement in the sucrose consumption rate (72 %) and the L-serine productivity (67 %). In fed-batch fermentation, 42.62 g/L of L-serine accumulation was achieved with a productivity of 0.44 g/L/h and yield of 0.21 g/g sucrose, which was the highest production of L-serine from sugars to date. The results demonstrated that combined metabolic and bioprocess engineering strategies could minimize by-product accumulation and improve L-serine productivity.

  3. A Fast and Accurate Algorithm for l1 Minimization Problems in Compressive Sampling (Preprint)

    DTIC Science & Technology

    2013-01-22

    However, updating uk+1 via the formulation of Step 2 in Algorithm 1 can be implemented through the use of the component-wise Gauss - Seidel iteration which...may accelerate the rate of convergence of the algorithm and therefore reduce the total CPU-time consumed. The efficiency of component-wise Gauss - Seidel ...Micchelli, L. Shen, and Y. Xu, A proximity algorithm accelerated by Gauss - Seidel iterations for L1/TV denoising models, Inverse Problems, 28 (2012), p

  4. Maximum-entropy probability distributions under Lp-norm constraints

    NASA Technical Reports Server (NTRS)

    Dolinar, S.

    1991-01-01

    Continuous probability density functions and discrete probability mass functions are tabulated which maximize the differential entropy or absolute entropy, respectively, among all probability distributions with a given L sub p norm (i.e., a given pth absolute moment when p is a finite integer) and unconstrained or constrained value set. Expressions for the maximum entropy are evaluated as functions of the L sub p norm. The most interesting results are obtained and plotted for unconstrained (real valued) continuous random variables and for integer valued discrete random variables. The maximum entropy expressions are obtained in closed form for unconstrained continuous random variables, and in this case there is a simple straight line relationship between the maximum differential entropy and the logarithm of the L sub p norm. Corresponding expressions for arbitrary discrete and constrained continuous random variables are given parametrically; closed form expressions are available only for special cases. However, simpler alternative bounds on the maximum entropy of integer valued discrete random variables are obtained by applying the differential entropy results to continuous random variables which approximate the integer valued random variables in a natural manner. All the results are presented in an integrated framework that includes continuous and discrete random variables, constraints on the permissible value set, and all possible values of p. Understanding such as this is useful in evaluating the performance of data compression schemes.

  5. Reaction Norms in Natural Conditions: How Does Metabolic Performance Respond to Weather Variations in a Small Endotherm Facing Cold Environments?

    PubMed Central

    Petit, Magali; Vézina, François

    2014-01-01

    Reaction norms reflect an organisms' capacity to adjust its phenotype to the environment and allows for identifying trait values associated with physiological limits. However, reaction norms of physiological parameters are mostly unknown for endotherms living in natural conditions. Black-capped chickadees (Poecile atricapillus) increase their metabolic performance during winter acclimatization and are thus good model to measure reaction norms in the wild. We repeatedly measured basal (BMR) and summit (Msum) metabolism in chickadees to characterize, for the first time in a free-living endotherm, reaction norms of these parameters across the natural range of weather variation. BMR varied between individuals and was weakly and negatively related to minimal temperature. Msum varied with minimal temperature following a Z-shape curve, increasing linearly between 24°C and −10°C, and changed with absolute humidity following a U-shape relationship. These results suggest that thermal exchanges with the environment have minimal effects on maintenance costs, which may be individual-dependent, while thermogenic capacity is responding to body heat loss. Our results suggest also that BMR and Msum respond to different and likely independent constraints. PMID:25426860

  6. Lateral prefrontal/orbitofrontal cortex has different roles in norm compliance in gain and loss domains: a transcranial direct current stimulation study.

    PubMed

    Yin, Yunlu; Yu, Hongbo; Su, Zhongbin; Zhang, Yuan; Zhou, Xiaolin

    2017-09-01

    Sanction is used by almost all known human societies to enforce fairness norm in resource distribution. Previous studies have consistently shown that the lateral prefrontal cortex (lPFC) and the adjacent orbitofrontal cortex (lOFC) play a causal role in mediating the effect of sanction threat on norm compliance. However, most of these studies were conducted in gain domain in which resources are distributed. Little is known about the mechanisms underlying norm compliance in loss domain in which individual sacrifices are needed. Here we employed a modified version of dictator game (DG) and high-definition transcranial direct current stimulation (HD-tDCS) to investigate to what extent lPFC/lOFC is involved in norm compliance (with and without sanction threat) in both gain- and loss-sharing contexts. Participants allocated a fixed total amount of monetary gain or loss between themselves and an anonymous partner in multiple rounds of the game. A computer program randomly decided whether a given round involved sanction threat for the participants. Results showed that disruption of the right lPFC/lOFC by tDCS increased the voluntary norm compliance in the gain domain, but not in the loss domain; tDCS on lPFC/lOFC had no effect on compliance under sanction threat in either the gain or loss domain. Our findings reveal a context-dependent nature of norm compliance and differential roles of lPFC/lOFC in norm compliance in gain and loss domains. © 2017 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

  7. The Iterative Reweighted Mixed-Norm Estimate for Spatio-Temporal MEG/EEG Source Reconstruction.

    PubMed

    Strohmeier, Daniel; Bekhti, Yousra; Haueisen, Jens; Gramfort, Alexandre

    2016-10-01

    Source imaging based on magnetoencephalography (MEG) and electroencephalography (EEG) allows for the non-invasive analysis of brain activity with high temporal and good spatial resolution. As the bioelectromagnetic inverse problem is ill-posed, constraints are required. For the analysis of evoked brain activity, spatial sparsity of the neuronal activation is a common assumption. It is often taken into account using convex constraints based on the l 1 -norm. The resulting source estimates are however biased in amplitude and often suboptimal in terms of source selection due to high correlations in the forward model. In this work, we demonstrate that an inverse solver based on a block-separable penalty with a Frobenius norm per block and a l 0.5 -quasinorm over blocks addresses both of these issues. For solving the resulting non-convex optimization problem, we propose the iterative reweighted Mixed Norm Estimate (irMxNE), an optimization scheme based on iterative reweighted convex surrogate optimization problems, which are solved efficiently using a block coordinate descent scheme and an active set strategy. We compare the proposed sparse imaging method to the dSPM and the RAP-MUSIC approach based on two MEG data sets. We provide empirical evidence based on simulations and analysis of MEG data that the proposed method improves on the standard Mixed Norm Estimate (MxNE) in terms of amplitude bias, support recovery, and stability.

  8. Graph-Based Norm Explanation

    NASA Astrophysics Data System (ADS)

    Croitoru, Madalina; Oren, Nir; Miles, Simon; Luck, Michael

    Norms impose obligations, permissions and prohibitions on individual agents operating as part of an organisation. Typically, the purpose of such norms is to ensure that an organisation acts in some socially (or mutually) beneficial manner, possibly at the expense of individual agent utility. In this context, agents are normaware if they are able to reason about which norms are applicable to them, and to decide whether to comply with or ignore them. While much work has focused on the creation of norm-aware agents, much less has been concerned with aiding system designers in understanding the effects of norms on a system. The ability to understand such norm effects can aid the designer in avoiding incorrect norm specification, eliminating redundant norms and reducing normative conflict. In this paper, we address the problem of norm understanding by providing explanations as to why a norm is applicable, violated, or in some other state. We make use of conceptual graph based semantics to provide a graphical representation of the norms within a system. Given knowledge of the current and historical state of the system, such a representation allows for explanation of the state of norms, showing for example why they may have been activated or violated.

  9. Fast computation of voxel-level brain connectivity maps from resting-state functional MRI using l₁-norm as approximation of Pearson's temporal correlation: proof-of-concept and example vector hardware implementation.

    PubMed

    Minati, Ludovico; Zacà, Domenico; D'Incerti, Ludovico; Jovicich, Jorge

    2014-09-01

    An outstanding issue in graph-based analysis of resting-state functional MRI is choice of network nodes. Individual consideration of entire brain voxels may represent a less biased approach than parcellating the cortex according to pre-determined atlases, but entails establishing connectedness for 1(9)-1(11) links, with often prohibitive computational cost. Using a representative Human Connectome Project dataset, we show that, following appropriate time-series normalization, it may be possible to accelerate connectivity determination replacing Pearson correlation with l1-norm. Even though the adjacency matrices derived from correlation coefficients and l1-norms are not identical, their similarity is high. Further, we describe and provide in full an example vector hardware implementation of l1-norm on an array of 4096 zero instruction-set processors. Calculation times <1000 s are attainable, removing the major deterrent to voxel-based resting-sate network mapping and revealing fine-grained node degree heterogeneity. L1-norm should be given consideration as a substitute for correlation in very high-density resting-state functional connectivity analyses. Copyright © 2014 IPEM. Published by Elsevier Ltd. All rights reserved.

  10. Interpreting a CMS excess in l l j j +missing -transverse-momentum with the golden cascade of the minimal supersymmetric standard model

    NASA Astrophysics Data System (ADS)

    Allanach, Ben; Kvellestad, Anders; Raklev, Are

    2015-06-01

    The CMS experiment recently reported an excess consistent with an invariant mass edge in opposite-sign same flavor leptons, when produced in conjunction with at least two jets and missing transverse momentum. We provide an interpretation of the edge in terms of (anti)squark pair production followed by the "golden cascade" decay for one of the squarks: q ˜ →χ˜2 0q →l ˜ l q →χ˜1 0q l l in the minimal supersymmetric standard model. A simplified model involving binos, winos, an on-shell slepton, and the first two generations of squarks fits the event rate and the invariant mass edge. We check consistency with a recent ATLAS search in a similar region, finding that much of the good-fit parameter space is still allowed at the 95% confidence level (C.L.). However, a combination of other LHC searches, notably two-lepton stop pair searches and jets plus p T, rule out all of the remaining parameter space at the 95% C.L.

  11. Sparse reconstruction of breast MRI using homotopic L0 minimization in a regional sparsified domain.

    PubMed

    Wong, Alexander; Mishra, Akshaya; Fieguth, Paul; Clausi, David A

    2013-03-01

    The use of MRI for early breast examination and screening of asymptomatic women has become increasing popular, given its ability to provide detailed tissue characteristics that cannot be obtained using other imaging modalities such as mammography and ultrasound. Recent application-oriented developments in compressed sensing theory have shown that certain types of magnetic resonance images are inherently sparse in particular transform domains, and as such can be reconstructed with a high level of accuracy from highly undersampled k-space data below Nyquist sampling rates using homotopic L0 minimization schemes, which holds great potential for significantly reducing acquisition time. An important consideration in the use of such homotopic L0 minimization schemes is the choice of sparsifying transform. In this paper, a regional differential sparsifying transform is investigated for use within a homotopic L0 minimization framework for reconstructing breast MRI. By taking local regional characteristics into account, the regional differential sparsifying transform can better account for signal variations and fine details that are characteristic of breast MRI than the popular finite differential transform, while still maintaining strong structure fidelity. Experimental results show that good breast MRI reconstruction accuracy can be achieved compared to existing methods.

  12. Gold nanoparticles functionalized with a fragment of the neural cell adhesion molecule L1 stimulate L1-mediated functions

    NASA Astrophysics Data System (ADS)

    Schulz, Florian; Lutz, David; Rusche, Norman; Bastús, Neus G.; Stieben, Martin; Höltig, Michael; Grüner, Florian; Weller, Horst; Schachner, Melitta; Vossmeyer, Tobias; Loers, Gabriele

    2013-10-01

    The neural cell adhesion molecule L1 is involved in nervous system development and promotes regeneration in animal models of acute and chronic injury of the adult nervous system. To translate these conducive functions into therapeutic approaches, a 22-mer peptide that encompasses a minimal and functional L1 sequence of the third fibronectin type III domain of murine L1 was identified and conjugated to gold nanoparticles (AuNPs) to obtain constructs that interact homophilically with the extracellular domain of L1 and trigger the cognate beneficial L1-mediated functions. Covalent conjugation was achieved by reacting mixtures of two cysteine-terminated forms of this L1 peptide and thiolated poly(ethylene) glycol (PEG) ligands (~2.1 kDa) with citrate stabilized AuNPs of two different sizes (~14 and 40 nm in diameter). By varying the ratio of the L1 peptide-PEG mixtures, an optimized layer composition was achieved that resulted in the expected homophilic interaction of the AuNPs. These AuNPs were stable as tested over a time period of 30 days in artificial cerebrospinal fluid and interacted with the extracellular domain of L1 on neurons and Schwann cells, as could be shown by using cells from wild-type and L1-deficient mice. In vitro, the L1-derivatized particles promoted neurite outgrowth and survival of neurons from the central and peripheral nervous system and stimulated Schwann cell process formation and proliferation. These observations raise the hope that, in combination with other therapeutic approaches, L1 peptide-functionalized AuNPs may become a useful tool to ameliorate the deficits resulting from acute and chronic injuries of the mammalian nervous system.The neural cell adhesion molecule L1 is involved in nervous system development and promotes regeneration in animal models of acute and chronic injury of the adult nervous system. To translate these conducive functions into therapeutic approaches, a 22-mer peptide that encompasses a minimal and functional L1

  13. Robust Principal Component Analysis Regularized by Truncated Nuclear Norm for Identifying Differentially Expressed Genes.

    PubMed

    Wang, Ya-Xuan; Gao, Ying-Lian; Liu, Jin-Xing; Kong, Xiang-Zhen; Li, Hai-Jun

    2017-09-01

    Identifying differentially expressed genes from the thousands of genes is a challenging task. Robust principal component analysis (RPCA) is an efficient method in the identification of differentially expressed genes. RPCA method uses nuclear norm to approximate the rank function. However, theoretical studies showed that the nuclear norm minimizes all singular values, so it may not be the best solution to approximate the rank function. The truncated nuclear norm is defined as the sum of some smaller singular values, which may achieve a better approximation of the rank function than nuclear norm. In this paper, a novel method is proposed by replacing nuclear norm of RPCA with the truncated nuclear norm, which is named robust principal component analysis regularized by truncated nuclear norm (TRPCA). The method decomposes the observation matrix of genomic data into a low-rank matrix and a sparse matrix. Because the significant genes can be considered as sparse signals, the differentially expressed genes are viewed as the sparse perturbation signals. Thus, the differentially expressed genes can be identified according to the sparse matrix. The experimental results on The Cancer Genome Atlas data illustrate that the TRPCA method outperforms other state-of-the-art methods in the identification of differentially expressed genes.

  14. Norm-Aware Socio-Technical Systems

    NASA Astrophysics Data System (ADS)

    Savarimuthu, Bastin Tony Roy; Ghose, Aditya

    The following sections are included: * Introduction * The Need for Norm-Aware Systems * Norms in human societies * Why should software systems be norm-aware? * Case Studies of Norm-Aware Socio-Technical Systems * Human-computer interactions * Virtual environments and multi-player online games * Extracting norms from big data and software repositories * Norms and Sustainability * Sustainability and green ICT * Norm awareness through software systems * Where To, From Here? * Conclusions

  15. Minimally invasive trans-sacral approach to L5-S1 interbody fusion: Preliminary results from 1 center and review of the literature.

    PubMed

    Bradley, W Daniel; Hisey, Michael S; Verma-Kurvari, Sunita; Ohnmeiss, Donna D

    2012-01-01

    varied among studies. The AxiaLIF approach allows access to the L5-S1 interspace without violating the annulus or longitudinal ligaments and with minimal risk to dorsal neural elements. It may be a viable alternative to other approaches to interbody fusion at the L5-S1 level. It is important that the patients be selected carefully and surgeons are familiar with the presacral anatomy and the surgical approach.

  16. How do social norms influence prosocial development?

    PubMed

    House, Bailey R

    2018-04-01

    Humans are both highly prosocial and extremely sensitive to social norms, and some theories suggest that norms are necessary to account for uniquely human forms of prosocial behavior and cooperation. Understanding how norms influence prosocial behavior is thus essential if we are to describe the psychology and development of prosocial behavior. In this article I review recent research from across the social sciences that provides (1) a theoretical model of how norms influence prosocial behavior, (2) empirical support for the model based on studies with adults and children, and (3) predictions about the psychological mechanisms through which norms shape prosocial behavior. I conclude by discussing the need for future studies into how prosocial behavior develops through emerging interactions between culturally varying norms, social cognition, emotions, and potentially genes. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Social and moral norm differences among Portuguese 1st and 6th year medical students towards their intention to comply with hand hygiene.

    PubMed

    Roberto, Magda S; Mearns, Kathryn; Silva, Silvia A

    2012-01-01

    This study examines social and moral norms towards the intention to comply with hand hygiene among Portuguese medical students from 1st and 6th years (N = 175; 121 from the 1st year, 54 from the 6th year). The study extended the theory of planned behaviour theoretical principles and hypothesised that both subjective and moral norms will be the best predictors of 1st and 6th year medical students' intention to comply with hand hygiene; however, these predictors ability to explain intention variance will change according to medical students' school year. Results indicated that the subjective norm, whose referent focuses on professors, is a relevant predictor of 1st year medical students' intention, while the subjective norm that emphasises the relevance of colleagues predicts the intentions of medical students from the 6th year. In terms of the moral norm, 6th year students' intention is better predicted by a norm that interferes with compliance; whereas intentions from 1st year students are better predicted by a norm that favours compliance. Implications of the findings highlight the importance of role models and mentors as key factors in teaching hand hygiene in medical undergraduate curricula.

  18. Adaptation and perceptual norms

    NASA Astrophysics Data System (ADS)

    Webster, Michael A.; Yasuda, Maiko; Haber, Sara; Leonard, Deanne; Ballardini, Nicole

    2007-02-01

    We used adaptation to examine the relationship between perceptual norms--the stimuli observers describe as psychologically neutral, and response norms--the stimulus levels that leave visual sensitivity in a neutral or balanced state. Adapting to stimuli on opposite sides of a neutral point (e.g. redder or greener than white) biases appearance in opposite ways. Thus the adapting stimulus can be titrated to find the unique adapting level that does not bias appearance. We compared these response norms to subjectively defined neutral points both within the same observer (at different retinal eccentricities) and between observers. These comparisons were made for visual judgments of color, image focus, and human faces, stimuli that are very different and may depend on very different levels of processing, yet which share the property that for each there is a well defined and perceptually salient norm. In each case the adaptation aftereffects were consistent with an underlying sensitivity basis for the perceptual norm. Specifically, response norms were similar to and thus covaried with the perceptual norm, and under common adaptation differences between subjectively defined norms were reduced. These results are consistent with models of norm-based codes and suggest that these codes underlie an important link between visual coding and visual experience.

  19. Minimally invasive versus conventional extracorporeal circulation in minimally invasive cardiac valve surgery.

    PubMed

    Baumbach, Hardy; Rustenbach, Christian; Michaelsen, Jens; Hipp, Gernot; Pressmar, Markus; Leinweber, Marco; Franke, Ulrich Friedrich Wilhelm

    2014-02-01

    Minimally invasive extracorporeal circulation (MECC) technology was applied predominantly in coronary surgery. Data regarding the application of MECC in minimally invasive valve surgery are missing largely. Patients undergoing isolated minimally invasive mitral or aortic valve procedures were allocated either to conventional extracorporeal circulation (CECC) group (n = 63) or MECC group (n = 105), and their prospectively generated data were analyzed. Demographic data were comparable between the groups regarding age (CECC vs. MECC: 71.0 ± 7.5 vs. 66.2 ± 10.1 years, p = 0.091) and logistic EuroSCORE I (6.2 ± 2.5 vs. 5.4 ± 3.0, p = 0.707). Hospital mortality was one patient in each group (1.6 vs. 1.0%, p = 0.688). The levels of leukocytes were lower in the MECC group (11.6 ± 3.2 vs. 9.4 ± 4.3 109/L, p = 0.040). Levels of platelets (137.2 ± 45.5 vs. 152.4 ± 50.3 109/L, p = 0.015) and hemoglobin (103.3 ± 11.3 vs. 107.3 ± 14.7 g/L, p = 0.017) were higher in the MECC group. Renal function was better preserved (creatinine: 1.1 ± 0.4 vs. 0.9 ± 0.2 mg/dL, p = 0.019). We were able to validate shorter time of postoperative ventilation (9.5 ± 15.1 vs. 6.3 ± 3.4 h, p = 0.054) as well as significantly shorter intensive care unit (ICU) stay (1.8 ± 1.3 vs. 1.2 ± 1.0 d, p = 0.005) for MECC patients. The course of C-reactive protein did not differ between the groups. We were able to prove the feasibility of MECC even in minimally invasive performed mitral and aortic valve procedures. In addition, the use of MECC provides decreased platelet consumption and less hemodilution. The use of MECC in these selected patients lead to a shorter ventilation time and ICU stay. Georg Thieme Verlag KG Stuttgart · New York.

  20. An iterative algorithm for L1-TV constrained regularization in image restoration

    NASA Astrophysics Data System (ADS)

    Chen, K.; Loli Piccolomini, E.; Zama, F.

    2015-11-01

    We consider the problem of restoring blurred images affected by impulsive noise. The adopted method restores the images by solving a sequence of constrained minimization problems where the data fidelity function is the ℓ1 norm of the residual and the constraint, chosen as the image Total Variation, is automatically adapted to improve the quality of the restored images. Although this approach is general, we report here the case of vectorial images where the blurring model involves contributions from the different image channels (cross channel blur). A computationally convenient extension of the Total Variation function to vectorial images is used and the results reported show that this approach is efficient for recovering nearly optimal images.

  1. Branch and bound algorithm for accurate estimation of analytical isotropic bidirectional reflectance distribution function models.

    PubMed

    Yu, Chanki; Lee, Sang Wook

    2016-05-20

    We present a reliable and accurate global optimization framework for estimating parameters of isotropic analytical bidirectional reflectance distribution function (BRDF) models. This approach is based on a branch and bound strategy with linear programming and interval analysis. Conventional local optimization is often very inefficient for BRDF estimation since its fitting quality is highly dependent on initial guesses due to the nonlinearity of analytical BRDF models. The algorithm presented in this paper employs L1-norm error minimization to estimate BRDF parameters in a globally optimal way and interval arithmetic to derive our feasibility problem and lower bounding function. Our method is developed for the Cook-Torrance model but with several normal distribution functions such as the Beckmann, Berry, and GGX functions. Experiments have been carried out to validate the presented method using 100 isotropic materials from the MERL BRDF database, and our experimental results demonstrate that the L1-norm minimization provides a more accurate and reliable solution than the L2-norm minimization.

  2. Injunctive Norms and Alcohol Consumption: A Revised Conceptualization

    PubMed Central

    Krieger, Heather; Neighbors, Clayton; Lewis, Melissa A.; LaBrie, Joseph W.; Foster, Dawn W.; Larimer, Mary E.

    2016-01-01

    Background Injunctive norms have been found to be important predictors of behaviors in many disciplines with the exception of alcohol research. This exception is likely due to a misconceptualization of injunctive norms for alcohol consumption. To address this, we outline and test a new conceptualization of injunctive norms and personal approval for alcohol consumption. Traditionally, injunctive norms have been assessed using Likert scale ratings of approval perceptions, whereas descriptive norms and individual behaviors are typically measured with behavioral estimates (i.e., number of drinks consumed per week, frequency of drinking, etc.). This makes comparisons between these constructs difficult because they are not similar conceptualizations of drinking behaviors. The present research evaluated a new representation of injunctive norms with anchors comparable to descriptive norms measures. Methods A study and a replication were conducted including 2,559 and 1,189 undergraduate students from three different universities. Participants reported on their alcohol-related consumption behaviors, personal approval of drinking, and descriptive and injunctive norms. Personal approval and injunctive norms were measured using both traditional measures and a new drink-based measure. Results Results from both studies indicated that drink-based injunctive norms were uniquely and positively associated with drinking whereas traditionally assessed injunctive norms were negatively associated with drinking. Analyses also revealed significant unique associations between drink-based injunctive norms and personal approval when controlling for descriptive norms. Conclusions These findings provide support for a modified conceptualization of personal approval and injunctive norms related to alcohol consumption and, importantly, offers an explanation and practical solution for the small and inconsistent findings related to injunctive norms and drinking in past studies. PMID:27030295

  3. Norms as Group-Level Constructs: Investigating School-Level Teen Pregnancy Norms and Behaviors.

    PubMed

    Mollborn, Stefanie; Domingue, Benjamin W; Boardman, Jason D

    2014-09-01

    Social norms are a group-level phenomenon, but past quantitative research has rarely measured them in the aggregate or considered their group-level properties. We used the school-based design of the National Longitudinal Study of Adolescent Health to measure normative climates regarding teen pregnancy across 75 U.S. high schools. We distinguished between the strength of a school's norm against teen pregnancy and the consensus around that norm. School-level norm strength and dissensus were strongly (r = -0.65) and moderately (r = 0.34) associated with pregnancy prevalence within schools, respectively. Normative climate partially accounted for observed racial differences in school pregnancy prevalence, but norms were a stronger predictor than racial composition. As hypothesized, schools with both a stronger average norm against teen pregnancy and greater consensus around the norm had the lowest pregnancy prevalence. Results highlight the importance of group-level normative processes and of considering the local school environment when designing policies to reduce teen pregnancy.

  4. Norms as Group-Level Constructs: Investigating School-Level Teen Pregnancy Norms and Behaviors

    PubMed Central

    Mollborn, Stefanie; Domingue, Benjamin W.; Boardman, Jason D.

    2015-01-01

    Social norms are a group-level phenomenon, but past quantitative research has rarely measured them in the aggregate or considered their group-level properties. We used the school-based design of the National Longitudinal Study of Adolescent Health to measure normative climates regarding teen pregnancy across 75 U.S. high schools. We distinguished between the strength of a school's norm against teen pregnancy and the consensus around that norm. School-level norm strength and dissensus were strongly (r = -0.65) and moderately (r = 0.34) associated with pregnancy prevalence within schools, respectively. Normative climate partially accounted for observed racial differences in school pregnancy prevalence, but norms were a stronger predictor than racial composition. As hypothesized, schools with both a stronger average norm against teen pregnancy and greater consensus around the norm had the lowest pregnancy prevalence. Results highlight the importance of group-level normative processes and of considering the local school environment when designing policies to reduce teen pregnancy. PMID:26074628

  5. Perceptual dehumanization of faces is activated by norm violations and facilitates norm enforcement.

    PubMed

    Fincher, Katrina M; Tetlock, Philip E

    2016-02-01

    This article uses methods drawn from perceptual psychology to answer a basic social psychological question: Do people process the faces of norm violators differently from those of others--and, if so, what is the functional significance? Seven studies suggest that people process these faces different and the differential processing makes it easier to punish norm violators. Studies 1 and 2 use a recognition-recall paradigm that manipulated facial-inversion and spatial frequency to show that people rely upon face-typical processing less when they perceive norm violators' faces. Study 3 uses a facial composite task to demonstrate that the effect is actor dependent, not action dependent, and to suggest that configural processing is the mechanism of perceptual change. Studies 4 and 5 use offset faces to show that configural processing is only attenuated when they belong to perpetrators who are culpable. Studies 6 and 7 show that people find it easier to punish inverted faces and harder to punish faces displayed in low spatial frequency. Taken together, these data suggest a bidirectional flow of causality between lower-order perceptual and higher-order cognitive processes in norm enforcement. PsycINFO Database Record (c) 2016 APA, all rights reserved.

  6. Anesthesia for minimally invasive neurosurgery.

    PubMed

    Prabhakar, Hemanshu; Mahajan, Charu; Kapoor, Indu

    2017-10-01

    With an ultimate aim of improving patients overall outcome and satisfaction, minimally invasive surgical approach is becoming more of a norm. The related anesthetic evidence has not expanded at the same rate as surgical and technological advancement. This article reviews the recent evidence on anesthesia and perioperative concerns for patients undergoing minimally invasive neurosurgery. Minimally invasive cranial and spinal surgeries have been made possible only by vast technological development. Points of surgical interest can be precisely located with the help of stereotaxy and neuronavigation and special endoscopes which decrease the tissue trauma. The principles of neuroanethesia remain the same, but few concerns are specific for each technique. Dexmedetomidine has a favorable profile for procedures carried out under sedation technique. As the new surgical techniques are coming up, lesser known anesthetic concerns may also come into light. Over the last year, little new information has been added to existing literature regarding anesthesia for minimally invasive neurosurgeries. Neuroanesthesia goals remain the same and less invasive surgical techniques do not translate into safe anesthesia. Specific concerns for each procedure should be taken into consideration.

  7. Coordinating bracket torque and incisor inclination : Part 3: Validity of bracket torque values in achieving norm inclinations.

    PubMed

    Zimmer, Bernd; Sino, Hiba

    2018-03-19

    To analyze common values of bracket torque (Andrews, Roth, MBT, Ricketts) for their validity in achieving incisor inclinations that are considered normal by different cephalometric standards. Using the equations developed in part 1 (eU1 (BOP) = 90° - BT (U1) - TCA (U1) + α 1 - α 2 and eL1 (BOP) = 90° - BT (L1) - TCA (L1) + β 1 - β 2 ) (abbreviations see part 1) and the mean values (± SD) obtained as statistical measures in parts 1 and 2 of the study (α 1 and β 1 [1.7° ± 0.7°], α 2 [3.6° ± 0.3°], β 2 [3.2° ± 0.4°], TCA (U1) [24.6° ± 3.6°] and TCA (L1) [22.9° ± 4.3°]) expected (= theoretically anticipated) values were calculated for upper and lower incisors (U1 and L1) and compared to targeted (= cephalometric norm) values. For U1, there was no overlapping between the ranges of expected and targeted values, as the lowest targeted value of (58.3°; Ricketts) was higher than the highest expected value (56.5°; Andrews) relative to the bisected occlusal plane (BOP). Thus all of these torque systems will aim for flatter inclinations than prescribed by any of the norm values. Depending on target values, the various bracket systems fell short by 1.8-5.5° (Andrews), 6.8-10.5° (Roth), 11.8-15.5° (MBT), or 16.8-20.5° (Ricketts). For L1, there was good agreement of the MBT system with the Ricketts and Björk target values (Δ0.1° and Δ-0.8°, respectively), and both the Roth and Ricketts systems came close to the Bergen target value (both Δ2.3°). Depending on target values, the ranges of deviation for L1 were 6.3-13.2° for Andrews (Class II prescription), 2.3°-9.2° for Roth, -3.7 to -3.2° for MBT, and 2.3-9.2° for Ricketts. Common values of upper incisor bracket torque do not have acceptable validity in achieving normal incisor inclinations. A careful selection of lower bracket torque may provide satisfactory matching with some of the targeted norm values.

  8. Social Norms about a Health Issue in Work Group Networks

    PubMed Central

    Frank, Lauren B.

    2015-01-01

    The purpose of this study is to advance theorizing about how small groups understand health issues through the use of social network analysis. To achieve this goal, an adapted cognitive social structure examines group social norms around a specific health issue, H1N1 flu prevention. As predicted, individual’s attitudes, self-efficacy, and perceived social norms were each positively associated with behavioral intentions for at least one of the H1N1 health behaviors studied. Moreover, collective norms of the whole group were also associated with behavioral intentions, even after controlling for how individual group members perceive those norms. For members of work groups in which pairs were perceived to agree in their support for H1N1 vaccination, the effect of individually perceived group norms on behavioral intentions was stronger than for groups with less agreement. PMID:26389934

  9. Norm overlap between many-body states: Uncorrelated overlap between arbitrary Bogoliubov product states

    NASA Astrophysics Data System (ADS)

    Bally, B.; Duguet, T.

    2018-02-01

    Background: State-of-the-art multi-reference energy density functional calculations require the computation of norm overlaps between different Bogoliubov quasiparticle many-body states. It is only recently that the efficient and unambiguous calculation of such norm kernels has become available under the form of Pfaffians [L. M. Robledo, Phys. Rev. C 79, 021302 (2009), 10.1103/PhysRevC.79.021302]. Recently developed particle-number-restored Bogoliubov coupled-cluster (PNR-BCC) and particle-number-restored Bogoliubov many-body perturbation (PNR-BMBPT) ab initio theories [T. Duguet and A. Signoracci, J. Phys. G 44, 015103 (2017), 10.1088/0954-3899/44/1/015103] make use of generalized norm kernels incorporating explicit many-body correlations. In PNR-BCC and PNR-BMBPT, the Bogoliubov states involved in the norm kernels differ specifically via a global gauge rotation. Purpose: The goal of this work is threefold. We wish (i) to propose and implement an alternative to the Pfaffian method to compute unambiguously the norm overlap between arbitrary Bogoliubov quasiparticle states, (ii) to extend the first point to explicitly correlated norm kernels, and (iii) to scrutinize the analytical content of the correlated norm kernels employed in PNR-BMBPT. Point (i) constitutes the purpose of the present paper while points (ii) and (iii) are addressed in a forthcoming paper. Methods: We generalize the method used in another work [T. Duguet and A. Signoracci, J. Phys. G 44, 015103 (2017), 10.1088/0954-3899/44/1/015103] in such a way that it is applicable to kernels involving arbitrary pairs of Bogoliubov states. The formalism is presently explicated in detail in the case of the uncorrelated overlap between arbitrary Bogoliubov states. The power of the method is numerically illustrated and benchmarked against known results on the basis of toy models of increasing complexity. Results: The norm overlap between arbitrary Bogoliubov product states is obtained under a closed

  10. How Does L1 and L2 Exposure Impact L1 Performance in Bilingual Children? Evidence from Polish-English Migrants to the United Kingdom

    PubMed Central

    Haman, Ewa; Wodniecka, Zofia; Marecka, Marta; Szewczyk, Jakub; Białecka-Pikul, Marta; Otwinowska, Agnieszka; Mieszkowska, Karolina; Łuniewska, Magdalena; Kołak, Joanna; Miękisz, Aneta; Kacprzak, Agnieszka; Banasik, Natalia; Foryś-Nogala, Małgorzata

    2017-01-01

    Most studies on bilingual language development focus on children’s second language (L2). Here, we investigated first language (L1) development of Polish-English early migrant bilinguals in four domains: vocabulary, grammar, phonological processing, and discourse. We first compared Polish language skills between bilinguals and their Polish non-migrant monolingual peers, and then investigated the influence of the cumulative exposure to L1 and L2 on bilinguals’ performance. We then examined whether high exposure to L1 could possibly minimize the gap between monolinguals and bilinguals. We analyzed data from 233 typically developing children (88 bilingual and 145 monolingual) aged 4;0 to 7;5 (years;months) on six language measures in Polish: receptive vocabulary, productive vocabulary, receptive grammar, productive grammar (sentence repetition), phonological processing (non-word repetition), and discourse abilities (narration). Information about language exposure was obtained via parental questionnaires. For each language task, we analyzed the data from the subsample of bilinguals who had completed all the tasks in question and from monolinguals matched one-on-one to the bilingual group on age, SES (measured by years of mother’s education), gender, non-verbal IQ, and short-term memory. The bilingual children scored lower than monolinguals in all language domains, except discourse. The group differences were more pronounced on the productive tasks (vocabulary, grammar, and phonological processing) and moderate on the receptive tasks (vocabulary and grammar). L1 exposure correlated positively with the vocabulary size and phonological processing. Grammar scores were not related to the levels of L1 exposure, but were predicted by general cognitive abilities. L2 exposure negatively influenced productive grammar in L1, suggesting possible L2 transfer effects on L1 grammatical performance. Children’s narrative skills benefitted from exposure to two languages: both L1

  11. ON THE BASIS PROPERTY OF THE HAAR SYSTEM IN THE SPACE \\mathscr{L}^{p(t)}(\\lbrack0,\\,1\\rbrack) AND THE PRINCIPLE OF LOCALIZATION IN THE MEAN

    NASA Astrophysics Data System (ADS)

    Sharapudinov, I. I.

    1987-02-01

    Let p=p(t) be a measurable function defined on \\lbrack0,\\,1\\rbrack. If p(t) is essentially bounded on \\lbrack0,\\,1\\rbrack, denote by \\mathscr{L}^{p(t)}(\\lbrack0,\\,1\\rbrack) the set of measurable functions f defined on \\lbrack0,\\,1\\rbrack for which \\int_0^1\\vert f(t)\\vert^{p(t)}dt<\\infty. The space \\mathscr{L}^{p(t)}(\\lbrack0,\\,1\\rbrack) with p(t)\\geqslant 1 is a normed space with norm \\displaystyle \\vert\\vert f\\vert\\vert _p=\\inf\\bigg\\{\\alpha>0:\\,\\int_0^1\\bigg\\vert\\frac{f(t)}{\\alpha}\\bigg\\vert^{p(t)}dt\\leqslant1\\bigg\\}.This paper examines the question of whether the Haar system is a basis in \\mathscr{L}^{p(t)}(\\lbrack0,\\,1\\rbrack). Conditions that are in a certain sense definitive on the function p(t) in order that the Haar system be a basis of \\mathscr{L}^{p(t)}(\\lbrack0,\\,1\\rbrack) are obtained. The concept of a localization principle in the mean is introduced, and its connection with the space \\mathscr{L}^{p(t)}(\\lbrack0,\\,1\\rbrack) is exhibited.Bibliography: 2 titles.

  12. Mobility of radionuclides and trace elements in soil from legacy NORM and undisturbed naturally 232Th-rich sites.

    PubMed

    Mrdakovic Popic, Jelena; Meland, Sondre; Salbu, Brit; Skipperud, Lindis

    2014-05-01

    Investigation of radionuclides (232Th and 238U) and trace elements (Cr, As and Pb) in soil from two legacy NORM (former mining sites) and one undisturbed naturally 232Th-rich site was conducted as a part of the ongoing environmental impact assessment in the Fen Complex area (Norway). The major objectives were to determine the radionuclide and trace element distribution and mobility in soils as well as to analyze possible differences between legacy NORM and surrounding undisturbed naturally 232Th-rich soils. Inhomogeneous soil distribution of radionuclides and trace elements was observed for each of the investigated sites. The concentration of 232Th was high (up to 1685 mg kg(-1), i.e., ∼7000 Bq kg(-1)) and exceeded the screening value for the radioactive waste material in Norway (1 Bq g(-1)). Based on the sequential extraction results, the majority of 232Th and trace elements were rather inert, irreversibly bound to soil. Uranium was found to be potentially more mobile, as it was associated with pH-sensitive soil phases, redox-sensitive amorphous soil phases and soil organic compounds. Comparison of the sequential extraction datasets from the three investigated sites revealed increased mobility of all analyzed elements at the legacy NORM sites in comparison with the undisturbed 232Th-rich site. Similarly, the distribution coefficients Kd (232Th) and Kd (238U) suggested elevated dissolution, mobility and transportation at the legacy NORM sites, especially at the decommissioned Nb-mining site (346 and 100 L kg(-1) for 232Th and 238U, respectively), while the higher sorption of radionuclides was demonstrated at the undisturbed 232Th-rich site (10,672 and 506 L kg(-1) for 232Th and 238U, respectively). In general, although the concentration ranges of radionuclides and trace elements were similarly wide both at the legacy NORM and at the undisturbed 232Th-rich sites, the results of soil sequential extractions together with Kd values supported the expected differences

  13. Radiological criteria for unrestricted use of sites containing norm

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bernhardt, D.E.; Rogers, V.C.; Nielson, K.K.

    1996-06-01

    Natural occurring radioactive materia (NORM) is redistributed in the environment as a result of many mineral recovery and processing industries. There are not federal regulations specifying criteria for NORM contaminated sites; however, several states have promulgated regulations. The regulations promulgated by the states generally focus on NORM from oil and gas production, the primary focus of the assessments for this paper. The criteria for residual NORM in soil are generally (1) 0.18 Bq g{sup -1} in the surface 15 cm of soil and 0.6 Bq g{sup -1} at depth or (2) 1.1 Bq g{sup -1}, with a limitation on themore » radon flux. The primary radiation dose pathways for unrestricted use of land are external gamma exposure and exposure related to indoor radon. Radiation doses vary by over an order of magnitude based on different ratios of {sup 226}Ra to {sup 228}Ra concentrations, biological uptake parameters related to NORM, and the different radon emanation factors for oil field scale and sludge. A {sup 226}Ra criterion of 1.1 Bq g{sup -1} results in a dose of about 2 mSv y{sup -1} from external gamma and about 3 mSv y{sup -1} from radon for a general crawl-space type residence home scenario. The chemical and physical characteristics of the NORM and site-specific factors are important considerations in the assessments. The radon dose would be about 3 times higher for NORM in sludge, vs. the assumption of pipe scale. The structural characteristics of residences (e.g., slab-on-grade, crawl-space, or trailer) also have a significant impact on the potential doses to residences.« less

  14. Silence and table manners: when environments activate norms.

    PubMed

    Joly, Janneke F; Stapel, Diederik A; Lindenberg, Siegwart M

    2008-08-01

    Two studies tested the conditions under which an environment (e.g., library, restaurant) raises the relevance of environment-specific social norms (e.g., being quiet, using table manners). As hypothesized, the relevance of such norms is raised when environments are goal relevant ("I am going there later") and when they are humanized with people or the remnants of their presence (e.g., a glass of wine on a table). Two studies show that goal-relevant environments and humanized environments raise the perceived importance of norms (Study 1) and the intention to conform to norms (Study 2). Interestingly, in both studies, these effects reach beyond norms related to the environments used in the studies.

  15. Banach spaces that realize minimal fillings

    NASA Astrophysics Data System (ADS)

    Bednov, B. B.; Borodin, P. A.

    2014-04-01

    It is proved that a real Banach space realizes minimal fillings for all its finite subsets (a shortest network spanning a fixed finite subset always exists and has the minimum possible length) if and only if it is a predual of L_1. The spaces L_1 are characterized in terms of Steiner points (medians). Bibliography: 25 titles.

  16. Computing global minimizers to a constrained B-spline image registration problem from optimal l1 perturbations to block match data

    PubMed Central

    Castillo, Edward; Castillo, Richard; Fuentes, David; Guerrero, Thomas

    2014-01-01

    Purpose: Block matching is a well-known strategy for estimating corresponding voxel locations between a pair of images according to an image similarity metric. Though robust to issues such as image noise and large magnitude voxel displacements, the estimated point matches are not guaranteed to be spatially accurate. However, the underlying optimization problem solved by the block matching procedure is similar in structure to the class of optimization problem associated with B-spline based registration methods. By exploiting this relationship, the authors derive a numerical method for computing a global minimizer to a constrained B-spline registration problem that incorporates the robustness of block matching with the global smoothness properties inherent to B-spline parameterization. Methods: The method reformulates the traditional B-spline registration problem as a basis pursuit problem describing the minimal l1-perturbation to block match pairs required to produce a B-spline fitting error within a given tolerance. The sparsity pattern of the optimal perturbation then defines a voxel point cloud subset on which the B-spline fit is a global minimizer to a constrained variant of the B-spline registration problem. As opposed to traditional B-spline algorithms, the optimization step involving the actual image data is addressed by block matching. Results: The performance of the method is measured in terms of spatial accuracy using ten inhale/exhale thoracic CT image pairs (available for download at www.dir-lab.com) obtained from the COPDgene dataset and corresponding sets of expert-determined landmark point pairs. The results of the validation procedure demonstrate that the method can achieve a high spatial accuracy on a significantly complex image set. Conclusions: The proposed methodology is demonstrated to achieve a high spatial accuracy and is generalizable in that in can employ any displacement field parameterization described as a least squares fit to block match

  17. SU-F-18C-14: Hessian-Based Norm Penalty for Weighted Least-Square CBCT Reconstruction

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sun, T; Sun, N; Tan, S

    Purpose: To develop a Hessian-based norm penalty for cone-beam CT (CBCT) reconstruction that has a similar ability in suppressing noise as the total variation (TV) penalty while avoiding the staircase effect and better preserving low-contrast objects. Methods: We extended the TV penalty to a Hessian-based norm penalty based on the Frobenius norm of the Hessian matrix of an image for CBCT reconstruction. The objective function was constructed using the penalized weighted least-square (PWLS) principle. An effective algorithm was developed to minimize the objective function using a majorization-minimization (MM) approach. We evaluated and compared the proposed penalty with the TV penaltymore » on a CatPhan 600 phantom and an anthropomorphic head phantom, each acquired at a low-dose protocol (10mA/10ms) and a high-dose protocol (80mA/12ms). For both penalties, contrast-to-noise (CNR) in four low-contrast regions-of-interest (ROIs) and the full-width-at-half-maximum (FWHM) of two point-like objects in constructed images were calculated and compared. Results: In the experiment of CatPhan 600 phantom, the Hessian-based norm penalty has slightly higher CNRs and approximately equivalent FWHM values compared with the TV penalty. In the experiment of the anthropomorphic head phantom at the low-dose protocol, the TV penalty result has several artificial piece-wise constant areas known as the staircase effect while in the Hessian-based norm penalty the image appears smoother and more similar to that of the FDK result using the high-dose protocol. Conclusion: The proposed Hessian-based norm penalty has a similar performance in suppressing noise to the TV penalty, but has a potential advantage in suppressing the staircase effect and preserving low-contrast objects. This work was supported in part by National Natural Science Foundation of China (NNSFC), under Grant Nos. 60971112 and 61375018, and Fundamental Research Funds for the Central Universities, under Grant No. 2012QN086

  18. Overview of NORM and activities by a NORM licensed permanent decontamination and waste processing facility

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mirro, G.A.

    1997-02-01

    This paper presents an overview of issues related to handling NORM materials, and provides a description of a facility designed for the processing of NORM contaminated equipment. With regard to handling NORM materials the author discusses sources of NORM, problems, regulations and disposal options, potential hazards, safety equipment, and issues related to personnel protection. For the facility, the author discusses: description of the permanent facility; the operations of the facility; the license it has for handling specific radioactive material; operating and safety procedures; decontamination facilities on site; NORM waste processing capabilities; and offsite NORM services which are available.

  19. Enhancing Sparsity by Reweighted l(1) Minimization

    DTIC Science & Technology

    2008-07-01

    recovery depends on the sparsity level k. The dashed curves represent a reweighted ℓ1 algorithm that outperforms the traditional unweighted ℓ1...approach (solid curve ). (a) Performance after 4 reweighting iterations as a function of ǫ. (b) Performance with fixed ǫ = 0.1 as a function of the number of...signal recovery (declared when ‖x0 − x‖ℓ∞ ≤ 10−3) for the unweighted ℓ1 algorithm as a function of the sparsity level k. The dashed curves represent the

  20. Base norms and discrimination of generalized quantum channels

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jenčová, A.

    2014-02-15

    We introduce and study norms in the space of hermitian matrices, obtained from base norms in positively generated subspaces. These norms are closely related to discrimination of so-called generalized quantum channels, including quantum states, channels, and networks. We further introduce generalized quantum decision problems and show that the maximal average payoffs of decision procedures are again given by these norms. We also study optimality of decision procedures, in particular, we obtain a necessary and sufficient condition under which an optimal 1-tester for discrimination of quantum channels exists, such that the input state is maximally entangled.

  1. A Truncated Nuclear Norm Regularization Method Based on Weighted Residual Error for Matrix Completion.

    PubMed

    Qing Liu; Zhihui Lai; Zongwei Zhou; Fangjun Kuang; Zhong Jin

    2016-01-01

    Low-rank matrix completion aims to recover a matrix from a small subset of its entries and has received much attention in the field of computer vision. Most existing methods formulate the task as a low-rank matrix approximation problem. A truncated nuclear norm has recently been proposed as a better approximation to the rank of matrix than a nuclear norm. The corresponding optimization method, truncated nuclear norm regularization (TNNR), converges better than the nuclear norm minimization-based methods. However, it is not robust to the number of subtracted singular values and requires a large number of iterations to converge. In this paper, a TNNR method based on weighted residual error (TNNR-WRE) for matrix completion and its extension model (ETNNR-WRE) are proposed. TNNR-WRE assigns different weights to the rows of the residual error matrix in an augmented Lagrange function to accelerate the convergence of the TNNR method. The ETNNR-WRE is much more robust to the number of subtracted singular values than the TNNR-WRE, TNNR alternating direction method of multipliers, and TNNR accelerated proximal gradient with Line search methods. Experimental results using both synthetic and real visual data sets show that the proposed TNNR-WRE and ETNNR-WRE methods perform better than TNNR and Iteratively Reweighted Nuclear Norm (IRNN) methods.

  2. Selection of regularization parameter for l1-regularized damage detection

    NASA Astrophysics Data System (ADS)

    Hou, Rongrong; Xia, Yong; Bao, Yuequan; Zhou, Xiaoqing

    2018-06-01

    The l1 regularization technique has been developed for structural health monitoring and damage detection through employing the sparsity condition of structural damage. The regularization parameter, which controls the trade-off between data fidelity and solution size of the regularization problem, exerts a crucial effect on the solution. However, the l1 regularization problem has no closed-form solution, and the regularization parameter is usually selected by experience. This study proposes two strategies of selecting the regularization parameter for the l1-regularized damage detection problem. The first method utilizes the residual and solution norms of the optimization problem and ensures that they are both small. The other method is based on the discrepancy principle, which requires that the variance of the discrepancy between the calculated and measured responses is close to the variance of the measurement noise. The two methods are applied to a cantilever beam and a three-story frame. A range of the regularization parameter, rather than one single value, can be determined. When the regularization parameter in this range is selected, the damage can be accurately identified even for multiple damage scenarios. This range also indicates the sensitivity degree of the damage identification problem to the regularization parameter.

  3. On a cost functional for H2/H(infinity) minimization

    NASA Technical Reports Server (NTRS)

    Macmartin, Douglas G.; Hall, Steven R.; Mustafa, Denis

    1990-01-01

    A cost functional is proposed and investigated which is motivated by minimizing the energy in a structure using only collocated feedback. Defined for an H(infinity)-norm bounded system, this cost functional also overbounds the H2 cost. Some properties of this cost functional are given, and preliminary results on the procedure for minimizing it are presented. The frequency domain cost functional is shown to have a time domain representation in terms of a Stackelberg non-zero sum differential game.

  4. Local social norms and military sexual stressors: do senior officers' norms matter?

    PubMed

    Murdoch, Maureen; Pryor, John Barron; Polusny, Melissa Anderson; Gackstetter, Gary D; Ripley, Diane Cowper

    2009-10-01

    To examine the relative importance of harassment-tolerant norms emanating from troops senior officers, immediate supervisors, and units on troops' sexual stressor experiences and to see whether associations differed by sex. Cross-sectional survey of all 681 willing and confirmed active duty troops enrolled in the VA National Enrollment Database between 1998 and 2002. Findings extended an earlier analysis. After adjusting for other significant correlates, senior officers' perceived tolerance of sexual harassment was not associated with the severity of sexual harassment troops reported (p = 0.64) or with the numbers of sexual identity challenges they reported (p = 0.11). Harassment-tolerant norms emanating from troops' units and immediate supervisors were associated with reporting more severe sexual harassment and more sexual identity challenges (all p < 0.003). Findings generalized across sex. Senior officers' norms did not appear to affect troops' reports of military sexual stressors, but unit norms and immediate supervisors' norms did.

  5. Circulating cell-derived microparticles in patients with minimally symptomatic obstructive sleep apnoea.

    PubMed

    Ayers, L; Ferry, B; Craig, S; Nicoll, D; Stradling, J R; Kohler, M

    2009-03-01

    Moderate-severe obstructive sleep apnoea (OSA) has been associated with several pro-atherogenic mechanisms and increased cardiovascular risk, but it is not known if minimally symptomatic OSA has similar effects. Circulating cell-derived microparticles have been shown to have pro-inflammatory, pro-coagulant and endothelial function-impairing effects, as well as to predict subclinical atherosclerosis and cardiovascular risk. In 57 patients with minimally symptomatic OSA, and 15 closely matched control subjects without OSA, AnnexinV-positive, platelet-, leukocyte- and endothelial cell-derived microparticles were measured by flow cytometry. In patients with OSA, median (interquartile range) levels of AnnexinV-positive microparticles were significantly elevated compared with control subjects: 2,586 (1,566-3,964) microL(-1) versus 1,206 (474-2,501) microL(-1), respectively. Levels of platelet-derived and leukocyte-derived microparticles were also significantly higher in patients with OSA (2,267 (1,102-3,592) microL(-1) and 20 (14-31) microL(-1), respectively) compared with control subjects (925 (328-2,068) microL(-1) and 15 (5-23) microL(-1), respectively). Endothelial cell-derived microparticle levels were similar in patients with OSA compared with control subjects (13 (8-25) microL(-1) versus 11 (6-17) microL(-1)). In patients with minimally symptomatic obstructive sleep apnoea, levels of AnnexinV-positive, platelet- and leukocyte-derived microparticles are elevated when compared with closely matched control subjects without obstructive sleep apnoea. These findings suggest that these patients may be at increased cardiovascular risk, despite being minimally symptomatic.

  6. Orthography-Induced Length Contrasts in the Second Language Phonological Systems of L2 Speakers of English: Evidence from Minimal Pairs.

    PubMed

    Bassetti, Bene; Sokolović-Perović, Mirjana; Mairano, Paolo; Cerni, Tania

    2018-06-01

    Research shows that the orthographic forms ("spellings") of second language (L2) words affect speech production in L2 speakers. This study investigated whether English orthographic forms lead L2 speakers to produce English homophonic word pairs as phonological minimal pairs. Targets were 33 orthographic minimal pairs, that is to say homophonic words that would be pronounced as phonological minimal pairs if orthography affects pronunciation. Word pairs contained the same target sound spelled with one letter or two, such as the /n/ in finish and Finnish (both /'fɪnɪʃ/ in Standard British English). To test for effects of length and type of L2 exposure, we compared Italian instructed learners of English, Italian-English late bilinguals with lengthy naturalistic exposure, and English natives. A reading-aloud task revealed that Italian speakers of English L2 produce two English homophonic words as a minimal pair distinguished by different consonant or vowel length, for instance producing the target /'fɪnɪʃ/ with a short [n] or a long [nː] to reflect the number of consonant letters in the spelling of the words finish and Finnish. Similar effects were found on the pronunciation of vowels, for instance in the orthographic pair scene-seen (both /siːn/). Naturalistic exposure did not reduce orthographic effects, as effects were found both in learners and in late bilinguals living in an English-speaking environment. It appears that the orthographic form of L2 words can result in the establishment of a phonological contrast that does not exist in the target language. Results have implications for models of L2 phonological development.

  7. Combination of minimal processing and irradiation to improve the microbiological safety of lettuce ( Lactuca sativa, L.)

    NASA Astrophysics Data System (ADS)

    Goularte, L.; Martins, C. G.; Morales-Aizpurúa, I. C.; Destro, M. T.; Franco, B. D. G. M.; Vizeu, D. M.; Hutzler, B. W.; Landgraf, M.

    2004-09-01

    The feasibility of gamma radiation in combination with minimal processing (MP) to reduce the number of Salmonella spp. and Escherichia coli O157:H7 in iceberg lettuce ( Lactuca sativa, L.) (shredded) was studied in order to increase the safety of the product. The reduction of the microbial population during the processing, the D10-values for Salmonella spp. and E. coli O157:H7 inoculated on shredded iceberg lettuce as well as the sensory evaluation of the irradiated product were evaluated. The immersion in chlorine (200 ppm) reduced coliform and aerobic mesophilic microorganisms by 0.9 and 2.7 log, respectively. D-values varied from 0.16 to 0.23 kGy for Salmonella spp. and from 0.11 to 0.12 kGy for E. coli O157:H7. Minimally processed iceberg lettuce exposed to 0.9 kGy does not show any change in sensory attributes. However, the texture of the vegetable was affected during the exposition to 1.1 kGy. The exposition of MP iceberg lettuce to 0.7 kGy reduced the population of Salmonella spp. by 4.0 log and E. coli by 6.8 log without impairing the sensory attributes. The combination of minimal process and gamma radiation to improve the safety of iceberg lettuce is feasible if good hygiene practices begins at farm stage.

  8. Peer Group Norms and Accountability Moderate the Effect of School Norms on Children's Intergroup Attitudes

    ERIC Educational Resources Information Center

    McGuire, Luke; Rutland, Adam; Nesdale, Drew

    2015-01-01

    The present study examined the interactive effects of school norms, peer norms, and accountability on children's intergroup attitudes. Participants (n = 229) aged 5-11 years, in a between-subjects design, were randomly assigned to a peer group with an inclusion or exclusion norm, learned their school either had an inclusion norm or not, and were…

  9. L^1 -optimality conditions for the circular restricted three-body problem

    NASA Astrophysics Data System (ADS)

    Chen, Zheng

    2016-11-01

    In this paper, the L^1 -minimization for the translational motion of a spacecraft in the circular restricted three-body problem (CRTBP) is considered. Necessary conditions are derived by using the Pontryagin Maximum Principle (PMP), revealing the existence of bang-bang and singular controls. Singular extremals are analyzed, recalling the existence of the Fuller phenomenon according to the theories developed in (Marchal in J Optim Theory Appl 11(5):441-486, 1973; Zelikin and Borisov in Theory of Chattering Control with Applications to Astronautics, Robotics, Economics, and Engineering. Birkhäuser, Basal 1994; in J Math Sci 114(3):1227-1344, 2003). The sufficient optimality conditions for the L^1 -minimization problem with fixed endpoints have been developed in (Chen et al. in SIAM J Control Optim 54(3):1245-1265, 2016). In the current paper, we establish second-order conditions for optimal control problems with more general final conditions defined by a smooth submanifold target. In addition, the numerical implementation to check these optimality conditions is given. Finally, approximating the Earth-Moon-Spacecraft system by the CRTBP, an L^1 -minimization trajectory for the translational motion of a spacecraft is computed by combining a shooting method with a continuation method in (Caillau et al. in Celest Mech Dyn Astron 114:137-150, 2012; Caillau and Daoud in SIAM J Control Optim 50(6):3178-3202, 2012). The local optimality of the computed trajectory is asserted thanks to the second-order optimality conditions developed.

  10. Injunctive social norms primacy over descriptive social norms in retirement savings decisions.

    PubMed

    Croy, Gerry; Gerrans, Paul; Speelman, Craig

    2010-01-01

    Consistent with the global trend to shift responsibility for retirement income provision from the public purse to individuals has been encouragement to save more and to manage investment strategy. Analyzing data from 2,300 respondents to a randomly distributed questionnaire, this article focuses on the motivational importance of social norms. The study finds injunctive social norms (what is commonly approved or disapproved of) exert greater influence than descriptive social norms (what is commonly done) in predicting retirement savings intentions. Modeling employs the theory of planned behavior, and also finds injunctive social norm has predictive primacy over attitude and perceived behavioral control. Discussion advocates a balanced approach to intervention design, and identifies opportunities for the further study of normative message framing.

  11. Prosocial norms as a positive youth development construct: conceptual bases and implications for curriculum development.

    PubMed

    Siu, Andrew M H; Cheng, Howard C H; Leung, Mana C M

    2006-01-01

    Prosocial norms are clear, healthy, ethical standards, beliefs, and behavior guidelines that promote prosocial behavior and minimize health risks. The promotion of prosocial norms like altruism, solidarity, and volunteerism is an important aspect of positive youth development programs. From the literature, it is evident that a prosocial orientation is encouraged in traditional Chinese philosophy. Longitudinal studies have shown that prosocial behavior increases gradually over adolescence, and that the development of prosocial behavior is closely linked to the development of moral reasoning, perspective taking, and regulation of personal distress. It is noteworthy that females have a higher prosocial orientation than males, and peer influence could be a major mediating factor of interventions to foster prosocial norms and behavior during adolescence. This review also analyzes the mechanism underlying prosocial behavior using the cost-reward model, social cognitive theory, and stages of moral development. Role modeling, social reinforcements and evaluations, discussion of moral dilemmas, empathy skills training, and foot-in-the-door procedures are identified as useful strategies for fostering prosocial norms and behavior.

  12. Learning the Norm of Internality: NetNorm, a Connectionist Model

    ERIC Educational Resources Information Center

    Thierry, Bollon; Adeline, Paignon; Pascal, Pansu

    2011-01-01

    The objective of the present article is to show that connectionist simulations can be used to model some of the socio-cognitive processes underlying the learning of the norm of internality. For our simulations, we developed a connectionist model which we called NetNorm (based on Dual-Network formalism). This model is capable of simulating the…

  13. A ℓ2, 1 norm regularized multi-kernel learning for false positive reduction in Lung nodule CAD.

    PubMed

    Cao, Peng; Liu, Xiaoli; Zhang, Jian; Li, Wei; Zhao, Dazhe; Huang, Min; Zaiane, Osmar

    2017-03-01

    The aim of this paper is to describe a novel algorithm for False Positive Reduction in lung nodule Computer Aided Detection(CAD). In this paper, we describes a new CT lung CAD method which aims to detect solid nodules. Specially, we proposed a multi-kernel classifier with a ℓ 2, 1 norm regularizer for heterogeneous feature fusion and selection from the feature subset level, and designed two efficient strategies to optimize the parameters of kernel weights in non-smooth ℓ 2, 1 regularized multiple kernel learning algorithm. The first optimization algorithm adapts a proximal gradient method for solving the ℓ 2, 1 norm of kernel weights, and use an accelerated method based on FISTA; the second one employs an iterative scheme based on an approximate gradient descent method. The results demonstrates that the FISTA-style accelerated proximal descent method is efficient for the ℓ 2, 1 norm formulation of multiple kernel learning with the theoretical guarantee of the convergence rate. Moreover, the experimental results demonstrate the effectiveness of the proposed methods in terms of Geometric mean (G-mean) and Area under the ROC curve (AUC), and significantly outperforms the competing methods. The proposed approach exhibits some remarkable advantages both in heterogeneous feature subsets fusion and classification phases. Compared with the fusion strategies of feature-level and decision level, the proposed ℓ 2, 1 norm multi-kernel learning algorithm is able to accurately fuse the complementary and heterogeneous feature sets, and automatically prune the irrelevant and redundant feature subsets to form a more discriminative feature set, leading a promising classification performance. Moreover, the proposed algorithm consistently outperforms the comparable classification approaches in the literature. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  14. EQ-5D Portuguese population norms.

    PubMed

    Ferreira, Lara Noronha; Ferreira, Pedro L; Pereira, Luis N; Oppe, Mark

    2014-03-01

    The EQ-5D is a widely used preference-based measure. Normative data can be used as references to analyze the effects of healthcare, determine the burden of disease and enable regional or country comparisons. Population norms for the EQ-5D exist for other countries but have not been previously published for Portugal. The purpose of this study was to derive EQ-5D Portuguese population norms. The EQ-5D was applied by phone interview to a random sample of the Portuguese general population (n = 1,500) stratified by age, gender and region. The Portuguese value set was used to derive the EQ-5D index. Mean values were computed by gender and age groups, marital status, educational attainment, region and other variables to obtain the EQ-5D Portuguese norms. Health status declines with advancing age, and women reported worse health status than men. These results are similar to other EQ-5D population health studies. This study provides Portuguese population health-related quality of life data measured by the EQ-5D that can be used as population norms. These norms can be used to inform Portuguese policy makers, health care professionals and researchers in issues related to health care policy and planning and quantification of treatment effects on health status.

  15. Feasibility of minimally invasive radical prostatectomy in prostate cancer patients with high prostate-specific antigen: feasibility and 1-year outcomes.

    PubMed

    Do, Minh; Ragavan, Narasimhan; Dietel, Anja; Liatsikos, Evangelos; Anderson, Chris; McNeill, Alan; Stolzenburg, Jens-Uwe

    2012-10-01

    Urologists are cautious to offer minimally invasive radical prostatectomy in prostate cancer patients with high prostate-specific antigen (and therefore anticipated to have locally advanced or metastatic disease) because of concerns regarding lack of complete cure after minimally invasive radical prostatectomy and of worsening of continence if adjuvant radiotherapy is used. A retrospective review of our institutional database was carried out to identify patients with PSA ≥20 ng/mL who underwent minimally invasive radical prostatectomy between January 2002 and October 2010. Intraoperative, pathological, functional and short-term oncological outcomes were assessed. Overall, 233 patients met study criteria and were included in the analysis. The median prostate-specific antigen and prostate size were 28.5 ng/mL and 47 mL, respectively. Intraoperative complications were the following: rectal injury (0.86%) and blood transfusion (1.7%). Early postoperative complications included prolonged (>6 days) catheterization (9.4%), hematoma (4.7%), deep venous thrombosis (0.86%) and lymphocele (5.1%). Late postoperative complications included cerebrovascular accident (0.4%) and anastomotic stricture (0.8%). Pathology revealed poorly differentiated cancer in 48.9%, pT3/pT4 disease in 55.8%, positive margins in 28.3% and lymph node disease in 20.2% of the cases. Adverse pathological findings were more frequent in patients with prostate-specific antigen >40 ng/mL and (or) in those with locally advanced disease (pT3/pT4). In 62.2% of the cases, adjuvant radiotherapy was used. At 1-year follow up, 80% of patients did not show evidence of biochemical recurrence and 98.8% of them had good recovery of continence. Minimally invasive radical prostatectomy might represent a reasonable option in prostate cancer patients with high prostate-specific antigen as a part of a multimodality treatment approach. © 2012 The Japanese Urological Association.

  16. The minimal SUSY B - L model: simultaneous Wilson lines and string thresholds

    DOE PAGES

    Deen, Rehan; Ovrut, Burt A.; Purves, Austin

    2016-07-08

    In previous work, we presented a statistical scan over the soft supersymmetry breaking parameters of the minimal SUSY B - L model. For specificity of calculation, unification of the gauge parameters was enforced by allowing the two Z 3×Z 3 Wilson lines to have mass scales separated by approximately an order of magnitude. This introduced an additional “left-right” sector below the unification scale. In this paper, for three important reasons, we modify our previous analysis by demanding that the mass scales of the two Wilson lines be simultaneous and equal to an “average unification” mass U >. The present analysismore » is 1) more “natural” than the previous calculations, which were only valid in a very specific region of the Calabi-Yau moduli space, 2) the theory is conceptually simpler in that the left-right sector has been removed and 3) in the present analysis the lack of gauge unification is due to threshold effects — particularly heavy string thresholds, which we calculate statistically in detail. As in our previous work, the theory is renormalization group evolved from U > to the electroweak scale — being subjected, sequentially, to the requirement of radiative B - L and electroweak symmetry breaking, the present experimental lower bounds on the B - L vector boson and sparticle masses, as well as the lightest neutral Higgs mass of ~125 GeV. The subspace of soft supersymmetry breaking masses that satisfies all such constraints is presented and shown to be substantial.« less

  17. Dutch taboo norms.

    PubMed

    Roest, Sander A; Visser, Tessa A; Zeelenberg, René

    2018-04-01

    This article provides norms for general taboo, personal taboo, insult, valence, and arousal for 672 Dutch words, including 202 taboo words. Norms were collected using a 7-point Likert scale and based on ratings by psychology students from the Erasmus University Rotterdam in The Netherlands. The sample consisted of 87 psychology students (58 females, 29 males). We obtained high reliability based on split-half analyses. Our norms show high correlations with arousal and valence ratings collected by another Dutch word-norms study (Moors et al.,, Behavior Research Methods, 45, 169-177, 2013). Our results show that the previously found quadratic relation (i.e., U-shaped pattern) between valence and arousal also holds when only taboo words are considered. Additionally, words rated high on taboo tended to be rated low on valence, but some words related to sex rated high on both taboo and valence. Words that rated high on taboo rated high on insult, again with the exception of words related to sex many of which rated low on insult. Finally, words rated high on taboo and insult rated high on arousal. The Dutch Taboo Norms (DTN) database is a useful tool for researchers interested in the effects of taboo words on cognitive processing. The data associated with this paper can be accessed via the Open Science Framework ( https://osf.io/vk782/ ).

  18. Assessment for the management of NORM wastes in conventional hazardous and nonhazardous waste landfills.

    PubMed

    Mora, Juan C; Baeza, Antonio; Robles, Beatriz; Sanz, Javier

    2016-06-05

    Naturally Occurring Radioactive Materials (NORM) wastes are generated in huge quantities in several industries and their management has been carried out under considerations of industrial non-radioactive wastes, before the concern on the radioactivity content was included in the legislation. Therefore these wastes were conditioned using conventional methods and the waste disposals were designed to isolate toxic elements from the environment for long periods of time. Spanish regulation for these conventional toxic waste disposals includes conditions that assure adequate isolation to minimize the impact of the wastes to the environment in present and future conditions. After 1996 the radiological impact of the management of NORM wastes is considered and all the aspects related with natural radiations and the radiological control regarding the management of residues from NORM industries were developed in the new regulation. One option to be assessed is the disposal of NORM wastes in hazardous and non-hazardous waste disposals, as was done before this new regulation. This work analyses the management of NORM wastes in these landfills to derive the masses that can be disposed without considerable radiological impact. Generic dose assessments were carried out under highly conservative hypothesis and a discussion on the uncertainty and variability sources was included to provide consistency to the calculations. Copyright © 2016 Elsevier B.V. All rights reserved.

  19. Hybrid normed ideal perturbations of n-tuples of operators I

    NASA Astrophysics Data System (ADS)

    Voiculescu, Dan-Virgil

    2018-06-01

    In hybrid normed ideal perturbations of n-tuples of operators, the normed ideal is allowed to vary with the component operators. We begin extending to this setting the machinery we developed for normed ideal perturbations based on the modulus of quasicentral approximation and an adaptation of our non-commutative generalization of the Weyl-von Neumann theorem. For commuting n-tuples of hermitian operators, the modulus of quasicentral approximation remains essentially the same when Cn- is replaced by a hybrid n-tuple Cp1,…- , … , Cpn- , p1-1 + ⋯ + pn-1 = 1. The proof involves singular integrals of mixed homogeneity.

  20. Current Trends in the study of Gender Norms and Health Behaviors

    PubMed Central

    Fleming, Paul J.; Agnew-Brune, Christine

    2015-01-01

    Gender norms are recognized as one of the major social determinants of health and gender norms can have implications for an individual’s health behaviors. This paper reviews the recent advances in research on the role of gender norms on health behaviors most associated with morbidity and mortality. We find that (1) the study of gender norms and health behaviors is varied across different types of health behaviors, (2) research on masculinity and masculine norms appears to have taken on an increasing proportion of studies on the relationship between gender norms and health, and (3) we are seeing new and varied populations integrated into the study of gender norms and health behaviors. PMID:26075291

  1. Anisotropic norm-oriented mesh adaptation for a Poisson problem

    NASA Astrophysics Data System (ADS)

    Brèthes, Gautier; Dervieux, Alain

    2016-10-01

    We present a novel formulation for the mesh adaptation of the approximation of a Partial Differential Equation (PDE). The discussion is restricted to a Poisson problem. The proposed norm-oriented formulation extends the goal-oriented formulation since it is equation-based and uses an adjoint. At the same time, the norm-oriented formulation somewhat supersedes the goal-oriented one since it is basically a solution-convergent method. Indeed, goal-oriented methods rely on the reduction of the error in evaluating a chosen scalar output with the consequence that, as mesh size is increased (more degrees of freedom), only this output is proven to tend to its continuous analog while the solution field itself may not converge. A remarkable quality of goal-oriented metric-based adaptation is the mathematical formulation of the mesh adaptation problem under the form of the optimization, in the well-identified set of metrics, of a well-defined functional. In the new proposed formulation, we amplify this advantage. We search, in the same well-identified set of metrics, the minimum of a norm of the approximation error. The norm is prescribed by the user and the method allows addressing the case of multi-objective adaptation like, for example in aerodynamics, adaptating the mesh for drag, lift and moment in one shot. In this work, we consider the basic linear finite-element approximation and restrict our study to L2 norm in order to enjoy second-order convergence. Numerical examples for the Poisson problem are computed.

  2. Global Norms: Towards Some Guidelines for Aggregating Personality Norms across Countries

    ERIC Educational Resources Information Center

    Bartram, Dave

    2008-01-01

    The article discusses issues relating to the international use of personality inventories, especially those in which organizations make comparisons between people from differing cultures or countries or those with different languages. The focus is on the issue of norming and the use of national versus multinational norms. It is noted that…

  3. The minimal SUSY B - L model: from the unification scale to the LHC

    DOE PAGES

    Ovrut, Burt A.; Purves, Austin; Spinner, Sogee

    2015-06-26

    Here, this paper introduces a random statistical scan over the high-energy initial parameter space of the minimal SUSY B - L model — denoted as the B - L MSSM. Each initial set of points is renormalization group evolved to the electroweak scale — being subjected, sequentially, to the requirement of radiative B - L and electroweak symmetry breaking, the present experimental lower bounds on the B - L vector boson and sparticle masses, as well as the lightest neutral Higgs mass of ~125 GeV. The subspace of initial parameters that satisfies all such constraints is presented, shown to bemore » robust and to contain a wide range of different configurations of soft supersymmetry breaking masses. The low-energy predictions of each such “valid” point — such as the sparticle mass spectrum and, in particular, the LSP — are computed and then statistically analyzed over the full subspace of valid points. Finally, the amount of fine-tuning required is quantified and compared to the MSSM computed using an identical random scan. The B - L MSSM is shown to generically require less fine-tuninng.« less

  4. Computer-Delivered Social Norm Message Increases Pain Tolerance

    PubMed Central

    Pulvers, Kim; Schroeder, Jacquelyn; Limas, Eleuterio F.; Zhu, Shu-Hong

    2013-01-01

    Background Few experimental studies have been conducted on social determinants of pain tolerance. Purpose This study tests a brief, computer-delivered social norm message for increasing pain tolerance. Methods Healthy young adults (N=260; 44 % Caucasian; 27 % Hispanic) were randomly assigned into a 2 (social norm)×2 (challenge) cold pressor study, stratified by gender. They received standard instructions or standard instructions plus a message that contained artifically elevated information about typical performance of others. Results Those receiving a social norm message displayed significantly higher pain tolerance, F(1, 255)=26.95, p<.001, ηp2=.10 and pain threshold F(1, 244)=9.81, p=.002, ηp2=.04, but comparable pain intensity, p>.05. There were no interactions between condition and gender on any outcome variables, p>.05. Conclusions Social norms can significantly increase pain tolerance, even with a brief verbal message delivered by a video. PMID:24146086

  5. Concreteness norms for 1,659 French words: Relationships with other psycholinguistic variables and word recognition times.

    PubMed

    Bonin, Patrick; Méot, Alain; Bugaiska, Aurélia

    2018-02-12

    Words that correspond to a potential sensory experience-concrete words-have long been found to possess a processing advantage over abstract words in various lexical tasks. We collected norms of concreteness for a set of 1,659 French words, together with other psycholinguistic norms that were not available for these words-context availability, emotional valence, and arousal-but which are important if we are to achieve a better understanding of the meaning of concreteness effects. We then investigated the relationships of concreteness with these newly collected variables, together with other psycholinguistic variables that were already available for this set of words (e.g., imageability, age of acquisition, and sensory experience ratings). Finally, thanks to the variety of psychological norms available for this set of words, we decided to test further the embodied account of concreteness effects in visual-word recognition, championed by Kousta, Vigliocco, Vinson, Andrews, and Del Campo (Journal of Experimental Psychology: General, 140, 14-34, 2011). Similarly, we investigated the influences of concreteness in three word recognition tasks-lexical decision, progressive demasking, and word naming-using a multiple regression approach, based on the reaction times available in Chronolex (Ferrand, Brysbaert, Keuleers, New, Bonin, Méot, Pallier, Frontiers in Psychology, 2; 306, 2011). The norms can be downloaded as supplementary material provided with this article.

  6. Robust Ambiguity Estimation for an Automated Analysis of the Intensive Sessions

    NASA Astrophysics Data System (ADS)

    Kareinen, Niko; Hobiger, Thomas; Haas, Rüdiger

    2016-12-01

    Very Long Baseline Interferometry (VLBI) is a unique space-geodetic technique that can directly determine the Earth's phase of rotation, namely UT1. The daily estimates of the difference between UT1 and Coordinated Universal Time (UTC) are computed from one-hour long VLBI Intensive sessions. These sessions are essential for providing timely UT1 estimates for satellite navigation systems. To produce timely UT1 estimates, efforts have been made to completely automate the analysis of VLBI Intensive sessions. This requires automated processing of X- and S-band group delays. These data often contain an unknown number of integer ambiguities in the observed group delays. In an automated analysis with the c5++ software the standard approach in resolving the ambiguities is to perform a simplified parameter estimation using a least-squares adjustment (L2-norm minimization). We implement the robust L1-norm with an alternative estimation method in c5++. The implemented method is used to automatically estimate the ambiguities in VLBI Intensive sessions for the Kokee-Wettzell baseline. The results are compared to an analysis setup where the ambiguity estimation is computed using the L2-norm. Additionally, we investigate three alternative weighting strategies for the ambiguity estimation. The results show that in automated analysis the L1-norm resolves ambiguities better than the L2-norm. The use of the L1-norm leads to a significantly higher number of good quality UT1-UTC estimates with each of the three weighting strategies.

  7. Quality of life of the Indonesian general population: Test-retest reliability and population norms of the EQ-5D-5L and WHOQOL-BREF.

    PubMed

    Purba, Fredrick Dermawan; Hunfeld, Joke A M; Iskandarsyah, Aulia; Fitriana, Titi Sahidah; Sadarjoen, Sawitri S; Passchier, Jan; Busschbach, Jan J V

    2018-01-01

    The objective of this study is to obtain population norms and to assess test-retest reliability of EQ-5D-5L and WHOQOL-BREF for the Indonesian population. A representative sample of 1056 people aged 17-75 years was recruited from the Indonesian general population. We used a multistage stratified quota sampling method with respect to residence, gender, age, education level, religion and ethnicity. Respondents completed EQ-5D-5L and WHOQOL-BREF with help from an interviewer. Norms data for both instruments were reported. For the test-retest evaluations, a sub-sample of 206 respondents completed both instruments twice. The total sample and test-retest sub-sample were representative of the Indonesian general population. The EQ-5D-5L shows almost perfect agreement between the two tests (Gwet's AC: 0.85-0.99 and percentage agreement: 90-99%) regarding the five dimensions. However, the agreement of EQ-VAS and index scores can be considered as poor (ICC: 0.45 and 0.37 respectively). For the WHOQOL-BREF, ICCs of the four domains were between 0.70 and 0.79, which indicates moderate to good agreement. For EQ-5D-5L, it was shown that female and older respondents had lower EQ-index scores, whilst rural, younger and higher-educated respondents had higher EQ-VAS scores. For WHOQOL-BREF: male, younger, higher-educated, high-income respondents had the highest scores in most of the domains, overall quality of life, and health satisfaction. This study provides representative estimates of self-reported health status and quality of life for the general Indonesian population as assessed by the EQ-5D-5L and WHOQOL-BREF instruments. The descriptive system of the EQ-5D-5L and the WHOQOL-BREF have high test-retest reliability while the EQ-VAS and the index score of EQ-5D-5L show poor agreement between the two tests. Our results can be useful to researchers and clinicians who can compare their findings with respect to these concepts with those of the Indonesian general population.

  8. Children are sensitive to norms of giving.

    PubMed

    McAuliffe, Katherine; Raihani, Nichola J; Dunham, Yarrow

    2017-10-01

    People across societies engage in costly sharing, but the extent of such sharing shows striking cultural variation, highlighting the importance of local norms in shaping generosity. Despite this acknowledged role for norms, it is unclear when they begin to exert their influence in development. Here we use a Dictator Game to investigate the extent to which 4- to 9-year-old children are sensitive to selfish (give 20%) and generous (give 80%) norms. Additionally, we varied whether children were told how much other children give (descriptive norm) or what they should give according to an adult (injunctive norm). Results showed that children generally gave more when they were exposed to a generous norm. However, patterns of compliance varied with age. Younger children were more likely to comply with the selfish norm, suggesting a licensing effect. By contrast, older children were more influenced by the generous norm, yet capped their donations at 50%, perhaps adhering to a pre-existing norm of equality. Children were not differentially influenced by descriptive or injunctive norms, suggesting a primacy of norm content over norm format. Together, our findings indicate that while generosity is malleable in children, normative information does not completely override pre-existing biases. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. A Handful of Paragraphs on "Translation" and "Norms."

    ERIC Educational Resources Information Center

    Toury, Gideon

    1998-01-01

    Presents some thoughts on the issue of translation and norms, focusing on the relationships between social agreements, conventions, and norms; translational norms; acts of translation and translation events; norms and values; norms for translated texts versus norms for non-translated texts; and competing norms. Comments on the reactions to three…

  10. Synergies of carvacrol and 1,8-cineole to inhibit bacteria associated with minimally processed vegetables.

    PubMed

    de Sousa, Jossana Pereira; de Azerêdo, Geíza Alves; de Araújo Torres, Rayanne; da Silva Vasconcelos, Margarida Angélica; da Conceição, Maria Lúcia; de Souza, Evandro Leite

    2012-03-15

    This study assessed the occurrence of an enhancing inhibitory effect of the combined application of carvacrol and 1,8-cineole against bacteria associated with minimally processed vegetables using the determination of Fractional Inhibitory Concentration (FIC) index, time-kill assay in vegetable broth and application in vegetable matrices. Their effects, individually and in combination, on the sensory characteristics of the vegetables were also determined. Carvacrol and 1,8-cineole displayed Minimum Inhibitory Concentration (MIC) in a range of 0.6-2.5 and 5-20 μL/mL, respectively, against the organisms studied. FIC indices of the combined application of the compounds were 0.25 against Listeria monocytogenes, Aeromonas hydrophila and Pseudomonas fluorescens, suggesting a synergic interaction. Application of carvacrol and 1,8-cineole alone (MIC) or in a mixture (1/8 MIC+1/8 MIC or 1/4 MIC+1/4 MIC) in vegetable broth caused a significant decrease (p<0.05) in bacterial count over 24h. Mixtures of carvacrol and 1,8-cineole reduced (p<0.05) the inocula of all bacteria in vegetable broth and in experimentally inoculated fresh-cut vegetables. A similar efficacy was observed in the reduction of naturally occurring microorganisms in vegetables. Sensory evaluation revealed that the scores of the most-evaluated attributes fell between "like slightly" and "neither like nor dislike." The combination of carvacrol and 1,8-cineole at sub-inhibitory concentrations could constitute an interesting approach to sanitizing minimally processed vegetables. Copyright © 2011 Elsevier B.V. All rights reserved.

  11. Alternative sanitization methods for minimally processed lettuce in comparison to sodium hypochlorite.

    PubMed

    Bachelli, Mara Lígia Biazotto; Amaral, Rívia Darla Álvares; Benedetti, Benedito Carlos

    2013-01-01

    Lettuce is a leafy vegetable widely used in industry for minimally processed products, in which the step of sanitization is the crucial moment for ensuring a safe food for consumption. Chlorinated compounds, mainly sodium hypochlorite, are the most used in Brazil, but the formation of trihalomethanes from this sanitizer is a drawback. Then, the search for alternative methods to sodium hypochlorite has been emerging as a matter of great interest. The suitability of chlorine dioxide (60 mg L(-1)/10 min), peracetic acid (100 mg L(-1)/15 min) and ozonated water (1.2 mg L(-1)/1 min) as alternative sanitizers to sodium hypochlorite (150 mg L(-1) free chlorine/15 min) were evaluated. Minimally processed lettuce washed with tap water for 1 min was used as a control. Microbiological analyses were performed in triplicate, before and after sanitization, and at 3, 6, 9 and 12 days of storage at 2 ± 1 °C with the product packaged on LDPE bags of 60 μm. It was evaluated total coliforms, Escherichia coli, Salmonella spp., psicrotrophic and mesophilic bacteria, yeasts and molds. All samples of minimally processed lettuce showed absence of E. coli and Salmonella spp. The treatments of chlorine dioxide, peracetic acid and ozonated water promoted reduction of 2.5, 1.1 and 0.7 log cycle, respectively, on count of microbial load of minimally processed product and can be used as substitutes for sodium hypochlorite. These alternative compounds promoted a shelf-life of six days to minimally processed lettuce, while the shelf-life with sodium hypochlorite was 12 days.

  12. Convergence of Proximal Iteratively Reweighted Nuclear Norm Algorithm for Image Processing.

    PubMed

    Sun, Tao; Jiang, Hao; Cheng, Lizhi

    2017-08-25

    The nonsmooth and nonconvex regularization has many applications in imaging science and machine learning research due to its excellent recovery performance. A proximal iteratively reweighted nuclear norm algorithm has been proposed for the nonsmooth and nonconvex matrix minimizations. In this paper, we aim to investigate the convergence of the algorithm. With the Kurdyka-Łojasiewicz property, we prove the algorithm globally converges to a critical point of the objective function. The numerical results presented in this paper coincide with our theoretical findings.

  13. Social norms and prejudice against homosexuals.

    PubMed

    Pereira, Annelyse; Monteiro, Maria Benedicta; Camino, Leoncio

    2009-11-01

    Different studies regarding the role of norms on the expression of prejudice have shown that the anti-prejudice norm influences people to inhibit prejudice expressions. However, if norm pressure has led to a substantial decrease in the public expression of prejudice against certain targets (e.g., blacks, women, blind people), little theoretical and empirical attention has been paid to the role of this general norm regarding sexual minorities (e.g., prostitutes, lesbians and gays). In this sense, the issue we want to address is whether general anti-prejudice norms can reduce the expression of prejudice against homosexual individuals. In this research we investigate the effect of activating an anti-prejudice norm against homosexuals on blatant and subtle expressions of prejudice. The anti-prejudice norm was experimentally manipulated and its effects were observed on rejection to intimacy (blatant prejudice) and on positive-negative emotions (subtle prejudice) regarding homosexuals. 136 university students were randomly allocated to activated-norm and control conditions and completed a questionnaire that included norm manipulation and the dependent variables. A multivariate analysis of variance (MANOVA) as well as subsequent ANOVAS showed that only in the high normative pressure condition participants expressed less rejection to intimacy and less negative emotions against homosexuals, when compared to the simple norm-activation and the control conditions. Positive emotions, however, were similar both in the high normative pressure and the control conditions. We concluded that a high anti-prejudice pressure regarding homosexuals could reduce blatant prejudice but not subtle prejudice, considering that the expression of negative emotions decreased while the expression of positive emotions remained stable.

  14. Plasma chitinase 3-like 1 is persistently elevated during first month after minimally invasive colorectal cancer resection.

    PubMed

    Shantha Kumara, H M C; Gaita, David; Miyagaki, Hiromichi; Yan, Xiaohong; Hearth, Sonali Ac; Njoh, Linda; Cekic, Vesna; Whelan, Richard L

    2016-08-15

    To assess blood chitinase 3-like 1 (CHi3L1) levels for 2 mo after minimally invasive colorectal resection (MICR) for colorectal cancer (CRC). CRC patients in an Institutional Review Board approved data/plasma bank who underwent elective MICR for whom preoperative (PreOp), early postoperative (PostOp), and 1 or more late PostOp samples [postoperative day (POD) 7-27] available were included. Plasma CHi3L1 levels (ng/mL) were determined in duplicate by enzyme linked immunosorbent assay. PreOp and PostOp plasma sample were available for 80 MICR cancer patients for the study. The median PreOp CHi3L1 level was 56.8 CI: 41.9-78.6 ng/mL (n = 80). Significantly elevated (P < 0.001) median plasma levels (ng/mL) over PreOp levels were detected on POD1 (667.7 CI: 495.7, 771.7; n = 79), POD 3 (132.6 CI: 95.5, 173.7; n = 76), POD7-13 (96.4 CI: 67.7, 136.9; n = 62), POD14-20 (101.4 CI: 80.7, 287.4; n = 22), and POD 21-27 (98.1 CI: 66.8, 137.4; n = 20, P = 0.001). No significant difference in plasma levels were noted on POD27-41. Plasma CHi3L1 levels were significantly elevated for one month after MICR. Persistently elevated plasma CHi3L1 may support the growth of residual tumor and metastasis.

  15. Poisson image reconstruction with Hessian Schatten-norm regularization.

    PubMed

    Lefkimmiatis, Stamatios; Unser, Michael

    2013-11-01

    Poisson inverse problems arise in many modern imaging applications, including biomedical and astronomical ones. The main challenge is to obtain an estimate of the underlying image from a set of measurements degraded by a linear operator and further corrupted by Poisson noise. In this paper, we propose an efficient framework for Poisson image reconstruction, under a regularization approach, which depends on matrix-valued regularization operators. In particular, the employed regularizers involve the Hessian as the regularization operator and Schatten matrix norms as the potential functions. For the solution of the problem, we propose two optimization algorithms that are specifically tailored to the Poisson nature of the noise. These algorithms are based on an augmented-Lagrangian formulation of the problem and correspond to two variants of the alternating direction method of multipliers. Further, we derive a link that relates the proximal map of an l(p) norm with the proximal map of a Schatten matrix norm of order p. This link plays a key role in the development of one of the proposed algorithms. Finally, we provide experimental results on natural and biological images for the task of Poisson image deblurring and demonstrate the practical relevance and effectiveness of the proposed framework.

  16. Do social norms affect intended food choice?

    PubMed

    Croker, H; Whitaker, K L; Cooke, L; Wardle, J

    2009-01-01

    To evaluate the effect of social norms on intended fruit and vegetable intake. A two-stage design to i) compare the perceived importance of normative influences vs cost and health on dietary choices, and ii) test the prediction that providing information on social norms will increase intended fruit and vegetable consumption in an experimental study. Home-based interviews (N=1083; 46% men, 54% women) were carried out as part of the Office for National Statistics Omnibus Survey in November 2008. The public's perception of the importance of social norms was lower (M=2.1) than the perceived importance of cost (M=2.7) or health (M=3.4) (all p's<0.001) on a scale from 1 (not at all important) to 4 (very important). In contrast, results from the experimental study showed that intentions to eat fruit and vegetables were positively influenced by normative information (p=0.011) in men but not by health or cost information; none of the interventions affected women's intentions. People have little awareness of the influence of social norms but normative information can have a demonstrable impact on dietary intentions. Health promotion might profit from emphasising how many people are attempting to adopt healthy lifestyles rather than how many have poor diets.

  17. Social norms of accompanied young children and observed crossing behaviors.

    PubMed

    Rosenbloom, Tova; Sapir-Lavid, Yael; Hadari-Carmi, Ofri

    2009-01-01

    Social norms for accompanied young children and crossing behaviors were examined in two studies conducted in an Ultra-Orthodox Jewish community in Israel. In Study 1, road behaviors of young children crossing with and without accompaniment and older children were observed, and the actual social norm for accompanied school children younger than 9-years-old was examined. In Study 2, the perceived norm of accompaniment was tested by questionnaires. Young children who crossed without accompaniment exhibited poorer crossing skills compared to older children and to young children crossing with accompaniment. In the four locations observed, the actual accompaniment rate ranged between 15%-60%. The perceived social norm for child accompaniment was lower than the actual norm. The discussion refers to both theoretical issues and their practical implications.

  18. Growth of Sobolev Norms in Linear Schrödinger Equations with Quasi-Periodic Potential

    NASA Astrophysics Data System (ADS)

    Bourgain, J.

    In this paper, we consider the following problem. Let iut+Δu+V(x,t)u= 0 be a linear Schrödinger equation ( periodic boundary conditions) where V is a real, bounded, real analytic potential which is periodic in x and quasi periodic in t with diophantine frequency vector λ. Denote S(t) the corresponding flow map. Thus S(t) preserves the L2-norm and our aim is to study its behaviour on Hs(TD), s> 0. Our main result is the growth in time is at most logarithmic; thus if φ∈Hs, then More precisely, (*) is proven in 1D and 2D when V is small. We also exhibit examples showing that a growth of higher Sobolev norms may occur in this context and (*) is thus essentially best possible.

  19. Alcohol Use Disorders and Perceived Drinking Norms: Ethnic Differences in Israeli Adults

    PubMed Central

    Shmulewitz, Dvora; Wall, Melanie M.; Keyes, Katherine M.; Aharonovich, Efrat; Aivadyan, Christina; Greenstein, Eliana; Spivak, Baruch; Weizman, Abraham; Frisch, Amos; Hasin, Deborah

    2012-01-01

    Objective: Individuals’ perceptions of drinking acceptability in their society (perceived injunctive drinking norms) are widely assumed to explain ethnic group differences in drinking and alcohol use disorders (AUDs), but this has never been formally tested. Immigrants to Israel from the former Soviet Union (FSU) are more likely to drink and report AUD symptoms than other Israelis. We tested perceived drinking norms as a mediator of differences between FSU immigrants and other Israelis in drinking and AUDs. Method: Adult household residents (N = 1,349) selected from the Israeli population register were assessed with a structured interview measuring drinking, AUD symptoms, and perceived drinking norms. Regression analyses were used to produce odds ratios (OR) and risk ratios (RR) and 95% confidence intervals (CI) to test differences between FSU immigrants and other Israelis on binary and graded outcomes. Mediation of FSU effects by perceived drinking norms was tested with bootstrapping procedures. Results: FSU immigrants were more likely than other Israelis to be current drinkers (OR = 2.39, CI [1.61, 3.55]), have higher maximum number of drinks per day (RR = 1.88, CI [1.64, 2.16]), have any AUD (OR = 1.75, CI [1.16, 2.64]), score higher on a continuous measure of AUD (RR = 1.44, CI [1.12, 1.84]), and perceive more permissive drinking norms (p < .0001). For all four drinking variables, the FSU group effect was at least partially mediated by perceived drinking norms. Conclusions: This is the first demonstration that drinking norms mediate ethnic differences in AUDs. This work contributes to understanding ethnic group differences in drinking and AUDs, potentially informing etiologic research and public policy aimed at reducing alcohol-related harm. PMID:23036217

  20. Social norms and their influence on eating behaviours.

    PubMed

    Higgs, Suzanne

    2015-03-01

    Social norms are implicit codes of conduct that provide a guide to appropriate action. There is ample evidence that social norms about eating have a powerful effect on both food choice and amounts consumed. This review explores the reasons why people follow social eating norms and the factors that moderate norm following. It is proposed that eating norms are followed because they provide information about safe foods and facilitate food sharing. Norms are a powerful influence on behaviour because following (or not following) norms is associated with social judgements. Norm following is more likely when there is uncertainty about what constitutes correct behaviour and when there is greater shared identity with the norm referent group. Social norms may affect food choice and intake by altering self-perceptions and/or by altering the sensory/hedonic evaluation of foods. The same neural systems that mediate the rewarding effects of food itself are likely to reinforce the following of eating norms. Copyright © 2014 Elsevier Ltd. All rights reserved.

  1. Development and testing of the Youth Alcohol Norms Survey (YANS) instrument to measure youth alcohol norms and psychosocial influences.

    PubMed

    Burns, Sharyn K; Maycock, Bruce; Hildebrand, Janina; Zhao, Yun; Allsop, Steve; Lobo, Roanna; Howat, Peter

    2018-05-14

    This study aimed to develop and validate an online instrument to: (1) identify common alcohol-related social influences, norms and beliefs among adolescents; (2) clarify the process and pathways through which proalcohol norms are transmitted to adolescents; (3) describe the characteristics of social connections that contribute to the transmission of alcohol norms; and (4) identify the influence of alcohol marketing on adolescent norm development. The online Youth Alcohol Norms Survey (YANS) was administered in secondary schools in Western Australia PARTICIPANTS: Using a 2-week test-retest format, the YANS was administered to secondary school students (n=481, age=13-17 years, female 309, 64.2%). The development of the YANS was guided by social cognitive theory and comprised a systematic multistage process including evaluation of content and face validity. A 2-week test-retest format was employed. Exploratory factor analysis was conducted to determine the underlying factor structure of the instrument. Test-retest reliability was examined using intraclass correlation coefficient (ICC) and Cohen's kappa. A five-factor structure with meaningful components and robust factorial loads was identified, and the five factors were labelled as 'individual attitudes and beliefs', 'peer and community identity', 'sibling influences', 'school and community connectedness' and 'injunctive norms', respectively. The instrument demonstrated stability across the test-retest procedure (ICC=0.68-0.88, Cohen's kappa coefficient=0.69) for most variables. The results support the reliability and factorial validity of this instrument. The YANS presents a promising tool, which enables comprehensive assessment of reciprocal individual, behavioural and environmental factors that influence alcohol-related norms among adolescents. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise

  2. [French norms of imagery for pictures, for concrete and abstract words].

    PubMed

    Robin, Frédérique

    2006-09-01

    This paper deals with French norms for mental image versus picture agreement for 138 pictures and the imagery value for 138 concrete words and 69 abstract words. The pictures were selected from Snodgrass et Vanderwart's norms (1980). The concrete words correspond to the dominant naming response to the pictorial stimuli. The abstract words were taken from verbal associative norms published by Ferrand (2001). The norms were established according to two variables: 1) mental image vs. picture agreement, and 2) imagery value of words. Three other variables were controlled: 1) picture naming agreement; 2) familiarity of objects referred to in the pictures and the concrete words, and 3) subjective verbal frequency of words. The originality of this work is to provide French imagery norms for the three kinds of stimuli usually compared in research on dual coding. Moreover, these studies focus on figurative and verbal stimuli variations in visual imagery processes.

  3. Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation

    PubMed Central

    Jo, Stephanie Y.; Granowicz, Eric M.; Maillard, Ivan; Thomas, Dafydd

    2011-01-01

    Disruptor of telomeric silencing 1-like (Dot1l) is a histone 3 lysine 79 methyltransferase. Studies of constitutive Dot1l knockout mice show that Dot1l is essential for embryonic development and prenatal hematopoiesis. DOT1L also interacts with translocation partners of Mixed Lineage Leukemia (MLL) gene, which is commonly translocated in human leukemia. However, the requirement of Dot1l in postnatal hematopoiesis and leukemogenesis of MLL translocation proteins has not been conclusively shown. With a conditional Dot1l knockout mouse model, we examined the consequences of Dot1l loss in postnatal hematopoiesis and MLL translocation leukemia. Deletion of Dot1l led to pancytopenia and failure of hematopoietic homeostasis, and Dot1l-deficient cells minimally reconstituted recipient bone marrow in competitive transplantation experiments. In addition, MLL-AF9 cells required Dot1l for oncogenic transformation, whereas cells with other leukemic oncogenes, such as Hoxa9/Meis1 and E2A-HLF, did not. These findings illustrate a crucial role of Dot1l in normal hematopoiesis and leukemogenesis of specific oncogenes. PMID:21398221

  4. Plasma chitinase 3-like 1 is persistently elevated during first month after minimally invasive colorectal cancer resection

    PubMed Central

    Shantha Kumara, H M C; Gaita, David; Miyagaki, Hiromichi; Yan, Xiaohong; Hearth, Sonali AC; Njoh, Linda; Cekic, Vesna; Whelan, Richard L

    2016-01-01

    AIM To assess blood chitinase 3-like 1 (CHi3L1) levels for 2 mo after minimally invasive colorectal resection (MICR) for colorectal cancer (CRC). METHODS CRC patients in an Institutional Review Board approved data/plasma bank who underwent elective MICR for whom preoperative (PreOp), early postoperative (PostOp), and 1 or more late PostOp samples [postoperative day (POD) 7-27] available were included. Plasma CHi3L1 levels (ng/mL) were determined in duplicate by enzyme linked immunosorbent assay. RESULTS PreOp and PostOp plasma sample were available for 80 MICR cancer patients for the study. The median PreOp CHi3L1 level was 56.8 CI: 41.9-78.6 ng/mL (n = 80). Significantly elevated (P < 0.001) median plasma levels (ng/mL) over PreOp levels were detected on POD1 (667.7 CI: 495.7, 771.7; n = 79), POD 3 (132.6 CI: 95.5, 173.7; n = 76), POD7-13 (96.4 CI: 67.7, 136.9; n = 62), POD14-20 (101.4 CI: 80.7, 287.4; n = 22), and POD 21-27 (98.1 CI: 66.8, 137.4; n = 20, P = 0.001). No significant difference in plasma levels were noted on POD27-41. CONCLUSION Plasma CHi3L1 levels were significantly elevated for one month after MICR. Persistently elevated plasma CHi3L1 may support the growth of residual tumor and metastasis. PMID:27574553

  5. Injunctive Norms and Problem Gambling among College Students

    PubMed Central

    Lostutter, Ty W.; Whiteside, Ursula; Fossos, Nicole; Walker, Denise D.; Larimer, Mary E.

    2010-01-01

    Two studies examined the relationships among injunctive norms and college student gambling. In study 1 we evaluated the accuracy of perceptions of other students’ approval of gambling and the relationship between perceived approval and gambling behavior. In study 2 we evaluated gambling behavior as a function of perceptions of approval of other students, friends, and family. In study 1, which included 2524 college students, perceptions of other students’ approval of gambling were found to be overestimated and were negatively associated with gambling behavior. The results of study 2, which included 565 college students, replicated the findings of study 1 and revealed positive associations between gambling behavior and perceived approval of friends and family. Results highlight the complexity of injunctive norms and the importance of considering the reference group (e.g., peers, friends, family members) in their evaluation. Results also encourage caution in considering the incorporation of injunctive norms in prevention and intervention approaches. PMID:17394053

  6. Professional Norms Guiding School Principals' Pedagogical Leadership

    ERIC Educational Resources Information Center

    Leo, Ulf

    2015-01-01

    Purpose: The purpose of this paper is to identify and analyze the professional norms surrounding school development, with a special emphasis on school principals' pedagogical leadership. Design/methodology/approach: A norm perspective is used to identify possible links between legal norms, professional norms, and actions. The findings are based on…

  7. The Effects of Liking Norms and Descriptive Norms on Vegetable Consumption: A Randomized Experiment

    PubMed Central

    Thomas, Jason M.; Liu, Jinyu; Robinson, Eric L.; Aveyard, Paul; Herman, C. Peter; Higgs, Suzanne

    2016-01-01

    There is evidence that social norm messages can be used to promote the selection of fruit and vegetables in low habitual consumers of these foods but it is unclear whether this effect is sustained over time. It is also unclear whether information about others' liking for a food (liking norm) could have the same effect. Using a 2 × 5 × 2 experimental design we investigated the effects of exposure to various messages on later intake from a food buffet and whether any effects were sustained 24 h after exposure in both low and high consumers of vegetables. There were three factors: delay (immediate food selection vs. food selection 24 h after exposure), message type (liking norm, descriptive norm, health message, vegetable variety condition, and neutral control message), and habitual consumption (low vs. high). The buffet consisted of three raw vegetables, three energy-dense foods, and two dips. For vegetables and non-vegetables there were no main effects of message type, nor any main effect of delay. There was a significant message × habitual vegetable consumption interaction for vegetable consumption; however, follow up tests did not yield any significant effects. Examining each food individually, there were no main effects of message type, nor any main effect of delay, for any of the foods; however, there was a message × habitual vegetable consumption interaction for broccoli. Consumption of broccoli in the health message and descriptive norm conditions did not differ from the control neutral condition. However, habitually low consumers of vegetables increased their consumption of broccoli in the vegetable variety and liking norm conditions relative to habitual low vegetable consumers in the neutral control condition (p < 0.05). Further, investigation of the effects of the liking norm and vegetable variety condition on vegetable intake is warranted. This trial is listed as NCT02618174 at clinicaltrials.gov. PMID:27065913

  8. Facial Anthropometric Norms among Kosovo - Albanian Adults.

    PubMed

    Staka, Gloria; Asllani-Hoxha, Flurije; Bimbashi, Venera

    2017-09-01

    The development of an anthropometric craniofacial database is a necessary multidisciplinary proposal. The aim of this study was to establish facial anthropometric norms and to investigate into sexual dimorphism in facial variables among Kosovo Albanian adults. The sample included 204 students of Dental School, Faculty of Medicine, University of Pristina. Using direct anthropometry, a series of 8 standard facial measurements was taken on each subject with digital caliper with an accuracy of 0.01 mm (Boss, Hamburg-Germany). The normative data and percentile rankings were calculated. Gender differences in facial variables were analyzed using t- test for independent samples (p<0.05). The index of sexual dimorphism (ISD) and percentage of sexual dimorphism were calculated for each facial measurement. ormative data for all facial anthropometric measurements in males were higher than in females. Male average norms compared with the female average norms differed significantly from each other (p>0.05).The highest index of sexual dimorphism (ISD) was found for the lower facial height 1.120, for which the highest percentage of sexual dimorphism, 12.01%., was also found. The lowest ISD was found for intercanthal width, 1.022, accompanied with the lowest percentage of sexual dimorphism, 2.23%. The obtained results have established the facial anthropometric norms among Kosovo Albanian adults. Sexual dimorphism has been confirmed for each facial measurement.

  9. Visual coding of human bodies: perceptual aftereffects reveal norm-based, opponent coding of body identity.

    PubMed

    Rhodes, Gillian; Jeffery, Linda; Boeing, Alexandra; Calder, Andrew J

    2013-04-01

    Despite the discovery of body-selective neural areas in occipitotemporal cortex, little is known about how bodies are visually coded. We used perceptual adaptation to determine how body identity is coded. Brief exposure to a body (e.g., anti-Rose) biased perception toward an identity with opposite properties (Rose). Moreover, the size of this aftereffect increased with adaptor extremity, as predicted by norm-based, opponent coding of body identity. A size change between adapt and test bodies minimized the effects of low-level, retinotopic adaptation. These results demonstrate that body identity, like face identity, is opponent coded in higher-level vision. More generally, they show that a norm-based multidimensional framework, which is well established for face perception, may provide a powerful framework for understanding body perception.

  10. Oral-diadochokinesis rates across languages: English and Hebrew norms.

    PubMed

    Icht, Michal; Ben-David, Boaz M

    2014-01-01

    Oro-facial and speech motor control disorders represent a variety of speech and language pathologies. Early identification of such problems is important and carries clinical implications. A common and simple tool for gauging the presence and severity of speech motor control impairments is oral-diadochokinesis (oral-DDK). Surprisingly, norms for adult performance are missing from the literature. The goals of this study were: (1) to establish a norm for oral-DDK rate for (young to middle-age) adult English speakers, by collecting data from the literature (five studies, N=141); (2) to investigate the possible effect of language (and culture) on oral-DDK performance, by analyzing studies conducted in other languages (five studies, N=140), alongside the English norm; and (3) to find a new norm for adult Hebrew speakers, by testing 115 speakers. We first offer an English norm with a mean of 6.2syllables/s (SD=.8), and a lower boundary of 5.4syllables/s that can be used to indicate possible abnormality. Next, we found significant differences between four tested languages (English, Portuguese, Farsi and Greek) in oral-DDK rates. Results suggest the need to set language and culture sensitive norms for the application of the oral-DDK task world-wide. Finally, we found the oral-DDK performance for adult Hebrew speakers to be 6.4syllables/s (SD=.8), not significantly different than the English norms. This implies possible phonological similarities between English and Hebrew. We further note that no gender effects were found in our study. We recommend using oral-DDK as an important tool in the speech language pathologist's arsenal. Yet, application of this task should be done carefully, comparing individual performance to a set norm within the specific language. Readers will be able to: (1) identify the Speech-Language Pathologist assessment process using the oral-DDK task, by comparing an individual performance to the present English norm, (2) describe the impact of language

  11. Perceived peer drinking norms and responsible drinking in UK university settings.

    PubMed

    Robinson, Eric; Jones, Andrew; Christiansen, Paul; Field, Matt

    2014-09-01

    Heavy drinking is common among students at UK universities. US students overestimate how much their peers drink and correcting this through the use of social norm messages may promote responsible drinking. We tested whether there is an association between perceived campus drinking norms and usual drinking behavior in UK university students and whether norm messages about responsible drinking correct normative misperceptions and increase students' intentions to drink responsibly. 1,020 UK university students took part in an online study. Participants were exposed to one of five message types: a descriptive norm, an injunctive norm, a descriptive and injunctive norm, or one of two control messages. Message credibility was assessed. Afterwards participants completed measures of intentions to drink responsibly and we measured usual drinking habits and perceptions of peer drinking. Perceptions of peer drinking were associated modestly with usual drinking behavior, whereby participants who believed other students drank responsibly also drank responsibly. Norm messages changed normative perceptions, but not in the target population of participants who underestimated responsible drinking in their peers at baseline. Norm messages did not increase intentions to drink responsibly and although based on accurate data, norm messages were not seen as credible. In this UK based study, although perceived social norms about peer drinking were associated with individual differences in drinking habits, campus wide norm messages about responsible drinking did not affect students' intentions to drink more responsibly. More research is required to determine if this approach can be applied to UK settings.

  12. NORM Management in the Oil & Gas Industry

    NASA Astrophysics Data System (ADS)

    Cowie, Michael; Mously, Khalid; Fageeha, Osama; Nassar, Rafat

    2008-08-01

    It has been established that Naturally Occurring Radioactive Materials (NORM) accumulates at various locations along the oil/gas production process. Components such as wellheads, separation vessels, pumps, and other processing equipment can become NORM contaminated, and NORM can accumulate in sludge and other waste media. Improper handling and disposal of NORM contaminated equipment and waste can create a potential radiation hazard to workers and the environment. Saudi Aramco Environmental Protection Department initiated a program to identify the extent, form and level of NORM contamination associated with the company operations. Once identified the challenge of managing operations which had a NORM hazard was addressed in a manner that gave due consideration to workers and environmental protection as well as operations' efficiency and productivity. The benefits of shared knowledge, practice and experience across the oil & gas industry are seen as key to the establishment of common guidance on NORM management. This paper outlines Saudi Aramco's experience in the development of a NORM management strategy and its goals of establishing common guidance throughout the oil and gas industry.

  13. Combined shape and topology optimization for minimization of maximal von Mises stress

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lian, Haojie; Christiansen, Asger N.; Tortorelli, Daniel A.

    Here, this work shows that a combined shape and topology optimization method can produce optimal 2D designs with minimal stress subject to a volume constraint. The method represents the surface explicitly and discretizes the domain into a simplicial complex which adapts both structural shape and topology. By performing repeated topology and shape optimizations and adaptive mesh updates, we can minimize the maximum von Mises stress using the p-norm stress measure with p-values as high as 30, provided that the stress is calculated with sufficient accuracy.

  14. Combined shape and topology optimization for minimization of maximal von Mises stress

    DOE PAGES

    Lian, Haojie; Christiansen, Asger N.; Tortorelli, Daniel A.; ...

    2017-01-27

    Here, this work shows that a combined shape and topology optimization method can produce optimal 2D designs with minimal stress subject to a volume constraint. The method represents the surface explicitly and discretizes the domain into a simplicial complex which adapts both structural shape and topology. By performing repeated topology and shape optimizations and adaptive mesh updates, we can minimize the maximum von Mises stress using the p-norm stress measure with p-values as high as 30, provided that the stress is calculated with sufficient accuracy.

  15. Perceived eating norms and children's eating behaviour: An informational social influence account.

    PubMed

    Sharps, Maxine; Robinson, Eric

    2017-06-01

    There is initial evidence that beliefs about the eating behaviour of others (perceived eating norms) can influence children's vegetable consumption, but little research has examined the mechanisms explaining this effect. In two studies we aimed to replicate the effect that perceived eating norms have on children's vegetable consumption, and to explore mechanisms which may underlie the influence of perceived eating norms on children's vegetable consumption. Study 1 investigated whether children follow perceived eating norms due to a desire to maintain personal feelings of social acceptance. Study 2 investigated whether perceived eating norms influence eating behaviour because eating norms provide information which can remove uncertainty about how to behave. Across both studies children were exposed to vegetable consumption information of other children and their vegetable consumption was examined. In both studies children were influenced by perceived eating norms, eating more when led to believe others had eaten a large amount compared to when led to believe others had eaten no vegetables. In Study 1, children were influenced by a perceived eating norm regardless of whether they felt sure or unsure that other children accepted them. In Study 2, children were most influenced by a perceived eating norm if they were eating in a novel context in which it may have been uncertain how to behave, as opposed to an eating context that children had already encountered. Perceived eating norms may influence children's eating behaviour by removing uncertainty about how to behave, otherwise known as informational social influence. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  16. Gender Norms and Family Planning Practices Among Men in Western Jamaica.

    PubMed

    Walcott, Melonie M; Ehiri, John; Kempf, Mirjam C; Funkhouser, Ellen; Bakhoya, Marion; Aung, Maung; Zhang, Kui; Jolly, Pauline E

    2015-07-01

    The objective of this study was to identify the association between gender norms and family planning practices among men in Western Jamaica. A cross-sectional survey of 549 men aged 19 to 54 years attending or visiting four government-operated hospitals was conducted in 2011. Logistic regression models were used to identify factors associated with taking steps to prevent unwanted pregnancy, intention to have a large family size (three or more children), and fathering children with multiple women. Adjusted odds ratios (AORs) and 95% confidence intervals (CIs) were calculated from the models. Reduced odds for taking steps to prevent unwanted pregnancy among men with moderate (AOR = 0.5; 95% CI = 0.3-0.8) and high (AOR = 0.3; 95% CI = 0.1-0.6) support for inequitable gender norms was observed. Desiring large family size was associated with moderate (AOR = 2.0; 95% CI = 1.3-2.5) and high (AOR = 2.6; 95% CI = 1.5-4.3) support for macho scores. For men with two or more children (41%), there were increased odds of fathering children with multiple women among those who had moderate (AOR = 2.1; 95% CI = 1.0-4.4) and high (AOR = 2.4; 95% CI = 1.1-5.6) support for masculinity norms. Support for inequitable gender norms was associated with reduced odds of taking steps to prevent unwanted pregnancy, while support for masculinity norms was associated with desiring a large family size and fathering children with multiple women. These findings highlight the importance of including men and gender norms in family planning programs in Jamaica. © The Author(s) 2014.

  17. Lessons learned from public health campaigns and applied to anti-DWI norms development

    DOT National Transportation Integrated Search

    1995-05-01

    The purpose of this study was to examine norms development in past public health campaigns to direct lessons learned from those efforts to future anti-DNN'l programming. Three campaigns were selected for a multiple case study. The anti-smoking, anti-...

  18. Television Content Viewing Patterns: Some Clues from Societal Norms.

    ERIC Educational Resources Information Center

    McDonald, Daniel G.; Glynn, Carroll J.

    Focusing on how television viewing fits into a general model of consumer consumption patterns, a study examined (1) the extent to which the viewing of certain television content can be considered a "norm" of society, (2) similarities and differences between the norms for adults and those for children, and (3) some of the antecedents of…

  19. Development and testing of the Youth Alcohol Norms Survey (YANS) instrument to measure youth alcohol norms and psychosocial influences

    PubMed Central

    Maycock, Bruce; Hildebrand, Janina; Zhao, Yun; Allsop, Steve; Lobo, Roanna; Howat, Peter

    2018-01-01

    Objectives This study aimed to develop and validate an online instrument to: (1) identify common alcohol-related social influences, norms and beliefs among adolescents; (2) clarify the process and pathways through which proalcohol norms are transmitted to adolescents; (3) describe the characteristics of social connections that contribute to the transmission of alcohol norms; and (4) identify the influence of alcohol marketing on adolescent norm development. Setting The online Youth Alcohol Norms Survey (YANS) was administered in secondary schools in Western Australia Participants Using a 2-week test–retest format, the YANS was administered to secondary school students (n=481, age=13–17 years, female 309, 64.2%). Primary and secondary outcome measures The development of the YANS was guided by social cognitive theory and comprised a systematic multistage process including evaluation of content and face validity. A 2-week test–retest format was employed. Exploratory factor analysis was conducted to determine the underlying factor structure of the instrument. Test–retest reliability was examined using intraclass correlation coefficient (ICC) and Cohen’s kappa. Results A five-factor structure with meaningful components and robust factorial loads was identified, and the five factors were labelled as ‘individual attitudes and beliefs’, ‘peer and community identity’, ‘sibling influences’, ‘school and community connectedness’ and ‘injunctive norms’, respectively. The instrument demonstrated stability across the test–retest procedure (ICC=0.68–0.88, Cohen’s kappa coefficient=0.69) for most variables. Conclusions The results support the reliability and factorial validity of this instrument. The YANS presents a promising tool, which enables comprehensive assessment of reciprocal individual, behavioural and environmental factors that influence alcohol-related norms among adolescents. PMID:29764872

  20. Clinical characteristics of occult macular dystrophy in family with mutation of RP1l1 gene.

    PubMed

    Tsunoda, Kazushige; Usui, Tomoaki; Hatase, Tetsuhisa; Yamai, Satoshi; Fujinami, Kaoru; Hanazono, Gen; Shinoda, Kei; Ohde, Hisao; Akahori, Masakazu; Iwata, Takeshi; Miyake, Yozo

    2012-06-01

    To report the clinical characteristics of occult macular dystrophy (OMD) in members of one family with a mutation of the RP1L1 gene. Fourteen members with a p.Arg45Trp mutation in the RP1L1 gene were examined. The visual acuity, visual fields, fundus photographs, fluorescein angiograms, full-field electroretinograms, multifocal electroretinograms, and optical coherence tomographic images were examined. The clinical symptoms and signs and course of the disease were documented. All the members with the RP1L1 mutation except one woman had ocular symptoms and signs of OMD. The fundus was normal in all the patients during the entire follow-up period except in one patient with diabetic retinopathy. Optical coherence tomography detected the early morphologic abnormalities both in the photoreceptor inner/outer segment line and cone outer segment tip line. However, the multifocal electroretinograms were more reliable in detecting minimal macular dysfunction at an early stage of OMD. The abnormalities in the multifocal electroretinograms and optical coherence tomography observed in the OMD patients of different durations strongly support the contribution of RP1L1 mutation to the presence of this disease.

  1. Comparing Gifted and Nongifted African American and Euro-American Students on Cognitive and Academic Variables Using Local Norms

    ERIC Educational Resources Information Center

    Jordan, Kelli R.; Bain, Sherry K.; McCallum, R. Steve; Mee Bell, Sherry

    2012-01-01

    A total of 47 gifted and nongifted African American and Euro-American elementary students were rated by their teachers on a multidimensional instrument developed to minimize language considerations and to rely on local norms (Universal Multiple Abilities Scales [UMAS; McCallum & Bracken, 2012a]). Results from two factorial MANOVAs revealed no…

  2. Minimizing the effects of oxygen interference on l-lactate sensors by a single amino acid mutation in Aerococcus viridansl-lactate oxidase.

    PubMed

    Hiraka, Kentaro; Kojima, Katsuhiro; Lin, Chi-En; Tsugawa, Wakako; Asano, Ryutaro; La Belle, Jeffrey T; Sode, Koji

    2018-04-30

    l-lactate biosensors employing l-lactate oxidase (LOx) have been developed mainly to measure l-lactate concentration for clinical diagnostics, sports medicine, and the food industry. Some l-lactate biosensors employ artificial electron mediators, but these can negatively impact the detection of l-lactate by competing with the primary electron acceptor: molecular oxygen. In this paper, a strategic approach to engineering an AvLOx that minimizes the effects of oxygen interference on sensor strips was reported. First, we predicted an oxygen access pathway in Aerococcus viridans LOx (AvLOx) based on its crystal structure. This was subsequently blocked by a bulky amino acid substitution. The resulting Ala96Leu mutant showed a drastic reduction in oxidase activity using molecular oxygen as the electron acceptor and a small increase in dehydrogenase activity employing an artificial electron acceptor. Secondly, the Ala96Leu mutant was immobilized on a screen-printed carbon electrode using glutaraldehyde cross-linking method. Amperometric analysis was performed with potassium ferricyanide as an electron mediator under argon or atmospheric conditions. Under argon condition, the response current increased linearly from 0.05 to 0.5mM l-lactate for both wild-type and Ala96Leu. However, under atmospheric conditions, the response of wild-type AvLOx electrode was suppressed by 9-12% due to oxygen interference. The Ala96Leu mutant maintained 56-69% of the response current at the same l-lactate level and minimized the relative bias error to -19% from -49% of wild-type. This study provided significant insight into the enzymatic reaction mechanism of AvLOx and presented a novel approach to minimize oxygen interference in sensor applications, which will enable accurate detection of l-lactate concentrations. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. [Cleanliness Norms 1964-1975].

    PubMed

    Noelle-Neumann, E

    1976-01-01

    In 1964 the Institut für Demoskopie Allensbach made a first survey taking stock of norms concerning cleanliness in the Federal Republic of Germany. At that time, 78% of respondents thought that the vogue among young people of cultivating an unkempt look was past or on the wane (Table 1.). Today we know that this fashion was an indicator of more serious desires for change in many different areas like politics, sexual morality, education and that its high point was still to come. In the fall of 1975 a second survey, modelled on the one of 1964, was conducted. Again, it concentrated on norms, not on behavior. As expected, norms have changed over this period but not in a one-directional or simple manner. In general, people are much more large-minded about children's looks: neat, clean school-dress, properly combed hair, clean shoes, all this and also holding their things in order has become less important in 1975 (Table 2). To carry a clean handkerchief is becoming oldfashioned (Table 3). On the other hand, principles of bringing-up children have not loosened concerning personal hygiene - brushing ones teeth, washing hands, feet, and neck, clean fingernails (Table 4). On one item related to protection of the environment, namely throwing around waste paper, standards have even become more strict (Table 5). With regard to school-leavers, norms of personal hygiene have generally become more strict (Table 6). As living standards have gone up and the number of full bathrooms has risen from 42% to 75% of households, norms of personal hygiene have also increased: one warm bath a week seemed enough to 56% of adults in 1964, but to only 32% in 1975 (Table 7). Also standards for changing underwear have changed a lot: in 1964 only 12% of respondents said "every day", in 1975 48% said so (Table 8). Even more stringent norms are applied to young women (Tables 9/10). For comparison: 1964 there were automatic washing machines in 16%, 1975 in 79% of households. Answers to questions

  4. Retroperitoneal oblique corridor to the L2-S1 intervertebral discs in the lateral position: an anatomic study.

    PubMed

    Davis, Timothy T; Hynes, Richard A; Fung, Daniel A; Spann, Scott W; MacMillan, Michael; Kwon, Brian; Liu, John; Acosta, Frank; Drochner, Thomas E

    2014-11-01

    Access to the intervertebral discs from L2-S1 in one surgical position can be challenging. The transpsoas minimally invasive surgical (MIS) approach is preferred by many surgeons, but this approach poses potential risk to neural structures of the lumbar plexus as they course through the psoas. The lumbar plexus and iliac crest often restrict the L4-5 disc access, and the L5-S1 level has not been a viable option from a direct lateral approach. The purpose of the present study was to investigate an MIS oblique corridor to the L2-S1 intervertebral disc space in cadaveric specimens while keeping the specimens in a lateral decubitus position with minimal disruption of the psoas and lumbar plexus. Twenty fresh-frozen full-torso cadaveric specimens were dissected, and an oblique anatomical corridor to access the L2-S1 discs was examined. Measurements were taken in a static state and with mild retraction of the psoas. The access corridor was defined at L2-5 as the left lateral border of the aorta (or iliac artery) and the anterior medial border of the psoas. The L5-S1 corridor of access was defined transversely from the midsagittal line of the inferior endplate of L-5 to the medial border of the left common iliac vessel and vertically to the first vascular structure that crosses midline. The mean access corridor diameters in the static state and with mild psoas retraction, respectively, were as follows: at L2-3, 18.60 mm and 25.50 mm; at L3-4, 19.25 mm and 27.05 mm; and at L4-5, 15.00 mm and 24.45 mm. The L5-S1 corridor mean values were 14.75 mm transversely, from midline to the left common iliac vessel and 23.85 mm from the inferior endplate of L-5 cephalad to the first midline vessel. The oblique corridor allows access to the L2-S1 discs while keeping the patient in a lateral decubitus position without a break in the table. Minimal psoas retraction without significant tendon disruption allowed for a generous corridor to the disc space. The L5-S1 disc space can be

  5. Control of NORM at Eugene Island 341-A

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shuler, P.J.; Baudoin, D.A.; Weintritt, D.J.

    1995-12-31

    A field study at Eugene island 341-A, an offshore production platform in the Gulf of Mexico, was conducted to develop strategies for the cost-effective prevention of NORM (Naturally Occurring Radioactive Materials) deposits. The specific objectives of this study were to: (1) Determine the root cause for the NORM deposits at this facility, utilizing different diagnostic techniques. (2) Consider all engineering options that are designed to prevent NORM from forming. (3) Determine the most cost-effective engineering solution. An overall objective was to generalize the diagnostics and control methods developed for Eugene Island 341-A to other oil and gas production facilities, especiallymore » to platforms located in the Gulf of Mexico. This study determined that the NORM deposits found at Eugene Island 341-A stem from commingling incompatible produced waters at the surface. Wells completed in Sand Block A have a water containing a relatively high concentration of barium, while those formation brines in Sand Blocks B and C are high in sulfate. When these waters mix at the start of the fluid treatment facilities on the platform, barium sulfate forms. Radium that is present in the produced brines co-precipitates with the barium, thereby creating a radioactive barium sulfate scale deposit (NORM).« less

  6. Relationships among L1 Print Exposure and Early L1 Literacy Skills, L2 Aptitude, and L2 Proficiency

    ERIC Educational Resources Information Center

    Sparks, Richard L.; Patton, Jon; Ganschow, Leonore; Humbach, Nancy

    2012-01-01

    Authors examined the relationship between individual differences in L1 print exposure and differences in early L1 skills and later L2 aptitude, L2 proficiency, and L2 classroom achievement. Participants were administered measures of L1 word decoding, spelling, phonemic awareness, reading comprehension, receptive vocabulary, and listening…

  7. Impact of Norm Perceptions and Guilt on Audience Response to Anti-Smoking Norm PSAs: The Case of Korean Male Smokers

    ERIC Educational Resources Information Center

    Lee, Hyegyu; Paek, Hye-Jin

    2013-01-01

    Objective: To examine how norm appeals and guilt influence smokers' behavioural intention. Design: Quasi-experimental design. Setting: South Korea. Method: Two hundred and fifty-five male smokers were randomly assigned to descriptive, injunctive, or subjective anti-smoking norm messages. After they viewed the norm messages, their norm perceptions,…

  8. Native-likeness in second language lexical categorization reflects individual language history and linguistic community norms.

    PubMed

    Zinszer, Benjamin D; Malt, Barbara C; Ameel, Eef; Li, Ping

    2014-01-01

    SECOND LANGUAGE LEARNERS FACE A DUAL CHALLENGE IN VOCABULARY LEARNING: First, they must learn new names for the 100s of common objects that they encounter every day. Second, after some time, they discover that these names do not generalize according to the same rules used in their first language. Lexical categories frequently differ between languages (Malt et al., 1999), and successful language learning requires that bilinguals learn not just new words but new patterns for labeling objects. In the present study, Chinese learners of English with varying language histories and resident in two different language settings (Beijing, China and State College, PA, USA) named 67 photographs of common serving dishes (e.g., cups, plates, and bowls) in both Chinese and English. Participants' response patterns were quantified in terms of similarity to the responses of functionally monolingual native speakers of Chinese and English and showed the cross-language convergence previously observed in simultaneous bilinguals (Ameel et al., 2005). For English, bilinguals' names for each individual stimulus were also compared to the dominant name generated by the native speakers for the object. Using two statistical models, we disentangle the effects of several highly interactive variables from bilinguals' language histories and the naming norms of the native speaker community to predict inter-personal and inter-item variation in L2 (English) native-likeness. We find only a modest age of earliest exposure effect on L2 category native-likeness, but importantly, we find that classroom instruction in L2 negatively impacts L2 category native-likeness, even after significant immersion experience. We also identify a significant role of both L1 and L2 norms in bilinguals' L2 picture naming responses.

  9. Native-likeness in second language lexical categorization reflects individual language history and linguistic community norms

    PubMed Central

    Zinszer, Benjamin D.; Malt, Barbara C.; Ameel, Eef; Li, Ping

    2014-01-01

    Second language learners face a dual challenge in vocabulary learning: First, they must learn new names for the 100s of common objects that they encounter every day. Second, after some time, they discover that these names do not generalize according to the same rules used in their first language. Lexical categories frequently differ between languages (Malt et al., 1999), and successful language learning requires that bilinguals learn not just new words but new patterns for labeling objects. In the present study, Chinese learners of English with varying language histories and resident in two different language settings (Beijing, China and State College, PA, USA) named 67 photographs of common serving dishes (e.g., cups, plates, and bowls) in both Chinese and English. Participants’ response patterns were quantified in terms of similarity to the responses of functionally monolingual native speakers of Chinese and English and showed the cross-language convergence previously observed in simultaneous bilinguals (Ameel et al., 2005). For English, bilinguals’ names for each individual stimulus were also compared to the dominant name generated by the native speakers for the object. Using two statistical models, we disentangle the effects of several highly interactive variables from bilinguals’ language histories and the naming norms of the native speaker community to predict inter-personal and inter-item variation in L2 (English) native-likeness. We find only a modest age of earliest exposure effect on L2 category native-likeness, but importantly, we find that classroom instruction in L2 negatively impacts L2 category native-likeness, even after significant immersion experience. We also identify a significant role of both L1 and L2 norms in bilinguals’ L2 picture naming responses. PMID:25386149

  10. NORM regulations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gray, P.

    1997-02-01

    The author reviews the question of regulation for naturally occuring radioactive material (NORM), and the factors that have made this a more prominent concern today. Past practices have been very relaxed, and have often involved very poor records, the involvment of contractors, and the disposition of contaminated equipment back into commercial service. The rationale behind the establishment of regulations is to provide worker protection, to exempt low risk materials, to aid in scrap recycling, to provide direction for remediation and to examine disposal options. The author reviews existing regulations at federal and state levels, impending legislation, and touches on themore » issue of site remediation and potential liabilities affecting the release of sites contaminated by NORM.« less

  11. NORM management in the oil and gas industry.

    PubMed

    Cowie, M; Mously, K; Fageeha, O; Nassar, R

    2012-01-01

    It has been established that naturally occurring radioactive material (NORM) may accumulate at various locations along the oil and gas production process. Components such as wellheads, separation vessels, pumps, and other processing equipment can become contaminated with NORM, and NORM can accumulate in the form of sludge, scale, scrapings, and other waste media. This can create a potential radiation hazard to workers, the general public, and the environment if certain controls are not established. Saudi Aramco has developed NORM management guidelines, and is implementing a comprehensive strategy to address all aspects of NORM management that aim to enhance NORM monitoring; control of NORM-contaminated equipment; control of NORM waste handling and disposal; and protection, awareness, and training of workers. The benefits of shared knowledge, best practice, and experience across the oil and gas industry are seen as key to the establishment of common guidance. This paper outlines Saudi Aramco's experience in the development of a NORM management strategy, and its goals of establishing common guidance throughout the oil and gas industry. Copyright © 2012. Published by Elsevier Ltd.

  12. Minimally processed vegetable salads: microbial quality evaluation.

    PubMed

    Fröder, Hans; Martins, Cecília Geraldes; De Souza, Katia Leani Oliveira; Landgraf, Mariza; Franco, Bernadette D G M; Destro, Maria Teresa

    2007-05-01

    The increasing demand for fresh fruits and vegetables and for convenience foods is causing an expansion of the market share for minimally processed vegetables. Among the more common pathogenic microorganisms that can be transmitted to humans by these products are Listeria monocytogenes, Escherichia coli O157:H7, and Salmonella. The aim of this study was to evaluate the microbial quality of a selection of minimally processed vegetables. A total of 181 samples of minimally processed leafy salads were collected from retailers in the city of Sao Paulo, Brazil. Counts of total coliforms, fecal coliforms, Enterobacteriaceae, psychrotrophic microorganisms, and Salmonella were conducted for 133 samples. L. monocytogenes was assessed in 181 samples using the BAX System and by plating the enrichment broth onto Palcam and Oxford agars. Suspected Listeria colonies were submitted to classical biochemical tests. Populations of psychrotrophic microorganisms >10(6) CFU/g were found in 51% of the 133 samples, and Enterobacteriaceae populations between 10(5) and 106 CFU/g were found in 42% of the samples. Fecal coliform concentrations higher than 10(2) CFU/g (Brazilian standard) were found in 97 (73%) of the samples, and Salmonella was detected in 4 (3%) of the samples. Two of the Salmonella-positive samples had <10(2) CFU/g concentrations of fecal coliforms. L. monocytogenes was detected in only 1 (0.6%) of the 181 samples examined. This positive sample was simultaneously detected by both methods. The other Listeria species identified by plating were L. welshimeri (one sample of curly lettuce) and L. innocua (2 samples of watercress). The results indicate that minimally processed vegetables had poor microbiological quality, and these products could be a vehicle for pathogens such as Salmonella and L. monocytogenes.

  13. Norm, gender, and bribe-giving: Insights from a behavioral game.

    PubMed

    Lan, Tian; Hong, Ying-Yi

    2017-01-01

    Previous research has suggested that bribery is more normative in some countries than in others. To understand the underlying process, this paper examines the effects of social norm and gender on bribe-giving behavior. We argue that social norms provide information for strategic planning and impression management, and thus would impact participants' bribe amount. Besides, males are more agentic and focus more on impression management than females. We predicted that males would defy the norm in order to win when the amount of their bribe was kept private, but would conform to the norm when it was made public. To test this hypothesis, we conducted two studies using a competitive game. In each game, we asked three participants to compete in five rounds of creative tasks, and the winner was determined by a referee's subjective judgment of the participants' performance on the tasks. Participants were allowed to give bribes to the referee. Bribe-giving norms were manipulated in two domains: norm level (high vs. low) and norm context (private vs. public), in order to investigate the influence of informational and affiliational needs. Studies 1 and 2 consistently showed that individuals conformed to the norm level of bribe-giving while maintaining a relative advantage for economic benefit. Study 2 found that males gave larger bribes in the private context than in the public, whereas females gave smaller bribes in both contexts. We used a latent growth curve model (LGCM) to depict the development of bribe-giving behaviors during five rounds of competition. The results showed that gender, creative performance, and norm level all influence the trajectory of bribe-giving behavior.

  14. Norm, gender, and bribe-giving: Insights from a behavioral game

    PubMed Central

    Hong, Ying-yi

    2017-01-01

    Previous research has suggested that bribery is more normative in some countries than in others. To understand the underlying process, this paper examines the effects of social norm and gender on bribe-giving behavior. We argue that social norms provide information for strategic planning and impression management, and thus would impact participants’ bribe amount. Besides, males are more agentic and focus more on impression management than females. We predicted that males would defy the norm in order to win when the amount of their bribe was kept private, but would conform to the norm when it was made public. To test this hypothesis, we conducted two studies using a competitive game. In each game, we asked three participants to compete in five rounds of creative tasks, and the winner was determined by a referee’s subjective judgment of the participants’ performance on the tasks. Participants were allowed to give bribes to the referee. Bribe-giving norms were manipulated in two domains: norm level (high vs. low) and norm context (private vs. public), in order to investigate the influence of informational and affiliational needs. Studies 1 and 2 consistently showed that individuals conformed to the norm level of bribe-giving while maintaining a relative advantage for economic benefit. Study 2 found that males gave larger bribes in the private context than in the public, whereas females gave smaller bribes in both contexts. We used a latent growth curve model (LGCM) to depict the development of bribe-giving behaviors during five rounds of competition. The results showed that gender, creative performance, and norm level all influence the trajectory of bribe-giving behavior. PMID:29272291

  15. Minimal realization of right-handed gauge symmetry

    NASA Astrophysics Data System (ADS)

    Nomura, Takaaki; Okada, Hiroshi

    2018-01-01

    We propose a minimally extended gauge symmetry model with U (1 )R , where only the right-handed fermions have nonzero charges in the fermion sector. To achieve both anomaly cancellations and minimality, three right-handed neutrinos are naturally required, and the standard model Higgs has to have nonzero charge under this symmetry. Then we find that its breaking scale(Λ ) is restricted by precise measurement of neutral gauge boson in the standard model; therefore, O (10 ) TeV ≲Λ . We also discuss its testability of the new gauge boson and discrimination of U (1 )R model from U (1 )B-L one at collider physics such as LHC and ILC.

  16. An Abbreviated Tool for Assessing Feminine Norm Conformity: Psychometric Properties of the Conformity to Feminine Norms Inventory-45

    ERIC Educational Resources Information Center

    Parent, Mike C.; Moradi, Bonnie

    2011-01-01

    The Conformity to Feminine Norms Inventory-45 (CFNI-45; Parent & Moradi, 2010) is an important tool for assessing level of conformity to feminine gender norms and for investigating the implications of such norms for women's functioning. The authors of the present study assessed the factor structure, measurement invariance, reliability, and…

  17. A Review of Norms and Normative Multiagent Systems

    PubMed Central

    Mahmoud, Moamin A.; Ahmad, Mohd Sharifuddin; Mustapha, Aida

    2014-01-01

    Norms and normative multiagent systems have become the subjects of interest for many researchers. Such interest is caused by the need for agents to exploit the norms in enhancing their performance in a community. The term norm is used to characterize the behaviours of community members. The concept of normative multiagent systems is used to facilitate collaboration and coordination among social groups of agents. Many researches have been conducted on norms that investigate the fundamental concepts, definitions, classification, and types of norms and normative multiagent systems including normative architectures and normative processes. However, very few researches have been found to comprehensively study and analyze the literature in advancing the current state of norms and normative multiagent systems. Consequently, this paper attempts to present the current state of research on norms and normative multiagent systems and propose a norm's life cycle model based on the review of the literature. Subsequently, this paper highlights the significant areas for future work. PMID:25110739

  18. ℓ p-Norm Multikernel Learning Approach for Stock Market Price Forecasting

    PubMed Central

    Shao, Xigao; Wu, Kun; Liao, Bifeng

    2012-01-01

    Linear multiple kernel learning model has been used for predicting financial time series. However, ℓ 1-norm multiple support vector regression is rarely observed to outperform trivial baselines in practical applications. To allow for robust kernel mixtures that generalize well, we adopt ℓ p-norm multiple kernel support vector regression (1 ≤ p < ∞) as a stock price prediction model. The optimization problem is decomposed into smaller subproblems, and the interleaved optimization strategy is employed to solve the regression model. The model is evaluated on forecasting the daily stock closing prices of Shanghai Stock Index in China. Experimental results show that our proposed model performs better than ℓ 1-norm multiple support vector regression model. PMID:23365561

  19. ℓ(p)-Norm multikernel learning approach for stock market price forecasting.

    PubMed

    Shao, Xigao; Wu, Kun; Liao, Bifeng

    2012-01-01

    Linear multiple kernel learning model has been used for predicting financial time series. However, ℓ(1)-norm multiple support vector regression is rarely observed to outperform trivial baselines in practical applications. To allow for robust kernel mixtures that generalize well, we adopt ℓ(p)-norm multiple kernel support vector regression (1 ≤ p < ∞) as a stock price prediction model. The optimization problem is decomposed into smaller subproblems, and the interleaved optimization strategy is employed to solve the regression model. The model is evaluated on forecasting the daily stock closing prices of Shanghai Stock Index in China. Experimental results show that our proposed model performs better than ℓ(1)-norm multiple support vector regression model.

  20. Extensive theoretical/numerical comparative studies on H2 and generalised H2 norms in sampled-data systems

    NASA Astrophysics Data System (ADS)

    Kim, Jung Hoon; Hagiwara, Tomomichi

    2017-11-01

    This paper is concerned with linear time-invariant (LTI) sampled-data systems (by which we mean sampled-data systems with LTI generalised plants and LTI controllers) and studies their H2 norms from the viewpoint of impulse responses and generalised H2 norms from the viewpoint of the induced norms from L2 to L∞. A new definition of the H2 norm of LTI sampled-data systems is first introduced through a sort of intermediate standpoint of those for the existing two definitions. We then establish unified treatment of the three definitions of the H2 norm through a matrix function G(τ) defined on the sampling interval [0, h). This paper next considers the generalised H2 norms, in which two types of the L∞ norm of the output are considered as the temporal supremum magnitude under the spatial 2-norm and ∞-norm of a vector-valued function. We further give unified treatment of the generalised H2 norms through another matrix function F(θ) which is also defined on [0, h). Through a close connection between G(τ) and F(θ), some theoretical relationships between the H2 and generalised H2 norms are provided. Furthermore, appropriate extensions associated with the treatment of G(τ) and F(θ) to the closed interval [0, h] are discussed to facilitate numerical computations and comparisons of the H2 and generalised H2 norms. Through theoretical and numerical studies, it is shown that the two generalised H2 norms coincide with neither of the three H2 norms of LTI sampled-data systems even though all the five definitions coincide with each other when single-output continuous-time LTI systems are considered as a special class of LTI sampled-data systems. To summarise, this paper clarifies that the five control performance measures are mutually related with each other but they are also intrinsically different from each other.

  1. Bodies obliged and unbound: differentiated response tendencies for injunctive and descriptive social norms.

    PubMed

    Jacobson, Ryan P; Mortensen, Chad R; Cialdini, Robert B

    2011-03-01

    The authors suggest that injunctive and descriptive social norms engage different psychological response tendencies when made selectively salient. On the basis of suggestions derived from the focus theory of normative conduct and from consideration of the norms' functions in social life, the authors hypothesized that the 2 norms would be cognitively associated with different goals, would lead individuals to focus on different aspects of self, and would stimulate different levels of conflict over conformity decisions. Additionally, a unique role for effortful self-regulation was hypothesized for each type of norm-used as a means to resist conformity to descriptive norms but as a means to facilitate conformity for injunctive norms. Four experiments supported these hypotheses. Experiment 1 demonstrated differences in the norms' associations to the goals of making accurate/efficient decisions and gaining/maintaining social approval. Experiment 2 provided evidence that injunctive norms lead to a more interpersonally oriented form of self-awareness and to a greater feeling of conflict about conformity decisions than descriptive norms. In the final 2 experiments, conducted in the lab (Experiment 3) and in a naturalistic environment (Experiment 4), self-regulatory depletion decreased conformity to an injunctive norm (Experiments 3 and 4) and increased conformity to a descriptive norm (Experiment 4)-even though the norms advocated identical behaviors. By illustrating differentiated response tendencies for each type of social norm, this research provides new and converging support for the focus theory of normative conduct. (c) 2011 APA, all rights reserved

  2. The minimal-ABC trees with B1-branches.

    PubMed

    Dimitrov, Darko; Du, Zhibin; Fonseca, Carlos M da

    2018-01-01

    The atom-bond connectivity index (or, for short, ABC index) is a molecular structure descriptor bridging chemistry to graph theory. It is probably the most studied topological index among all numerical parameters of a graph that characterize its topology. For a given graph G = (V, E), the ABC index of G is defined as [Formula: see text], where di denotes the degree of the vertex i, and ij is the edge incident to the vertices i and j. A combination of physicochemical and the ABC index properties are commonly used to foresee the bioactivity of different chemical composites. Additionally, the applicability of the ABC index in chemical thermodynamics and other areas of chemistry, such as in dendrimer nanostars, benzenoid systems, fluoranthene congeners, and phenylenes is well studied in the literature. While finding of the graphs with the greatest ABC-value is a straightforward assignment, the characterization of the tree(s) with minimal ABC index is a problem largely open and has recently given rise to numerous studies and conjectures. A B1-branch of a graph is a pendent path of order 2. In this paper, we provide an important step forward to the full characterization of these minimal trees. Namely, we show that a minimal-ABC tree contains neither 4 nor 3 B1-branches. The case when the number of B1-branches is 2 is also considered.

  3. Serotonin and Social Norms

    PubMed Central

    Bilderbeck, Amy C.; Brown, Gordon D. A.; Read, Judi; Woolrich, Mark; Cowen, Phillip J.; Behrens, Tim E. J.

    2014-01-01

    How do people sustain resources for the benefit of individuals and communities and avoid the tragedy of the commons, in which shared resources become exhausted? In the present study, we examined the role of serotonin activity and social norms in the management of depletable resources. Healthy adults, alongside social partners, completed a multiplayer resource-dilemma game in which they repeatedly harvested from a partially replenishable monetary resource. Dietary tryptophan depletion, leading to reduced serotonin activity, was associated with aggressive harvesting strategies and disrupted use of the social norms given by distributions of other players’ harvests. Tryptophan-depleted participants more frequently exhausted the resource completely and also accumulated fewer rewards than participants who were not tryptophan depleted. Our findings show that rank-based social comparisons are crucial to the management of depletable resources, and that serotonin mediates responses to social norms. PMID:24815611

  4. The Moderating Role of Close versus Distal Peer Injunctive Norms and Interdependent Self-Construal in the Effects of Descriptive Norms on College Drinking.

    PubMed

    Yang, Bo

    2018-06-01

    Based on the theory of normative social behavior (Rimal & Real, 2005), this study examined the effects of descriptive norms, close versus distal peer injunctive norms, and interdependent self-construal on college students' intentions to consume alcohol. Results of a cross-sectional study conducted among U.S. college students (N = 581) found that descriptive norms, close, and distal peer injunctive norms had independent effects on college students' intentions to consume alcohol. Furthermore, close peer injunctive norms moderated the effects of descriptive norms on college students' intentions to consume alcohol and the interaction showed different patterns among students with a strong and weak interdependent self-construal. High levels of close peer injunctive norms weakened the relationship between descriptive norms and intentions to consume alcohol among students with a strong interdependent self-construal but strengthened the relationship between descriptive norms and intentions to consume alcohol among students with a weak interdependent self-construal. Implications of the findings for norms-based research and college drinking interventions are discussed.

  5. Time lag and communication in changing unpopular norms.

    PubMed

    Gërxhani, Klarita; Bruggeman, Jeroen

    2015-01-01

    Humans often coordinate their social lives through norms. When a large majority of people are dissatisfied with an existing norm, it seems obvious that they will change it. Often, however, this does not occur. We investigate how a time lag between individual support of a norm change and the change itself hinders such change, related to the critical mass of supporters needed to effectuate the change, and the (im)possibility of communicating about it. To isolate these factors, we utilize a laboratory experiment. As predicted, we find unambiguous effects of time lag on precluding norm change; a higher threshold for a critical mass does so as well. Communication facilitates choosing superior norms but it does not necessarily lead to norm change when the uncertainty on whether there will be a norm change in the future is high. Communication seems to help coordination on actions at the present but not the future. Hence, the uncertainty driven by time lag makes individuals choose the status quo, here the unpopular norm.

  6. Time Lag and Communication in Changing Unpopular Norms

    PubMed Central

    Gërxhani, Klarita; Bruggeman, Jeroen

    2015-01-01

    Humans often coordinate their social lives through norms. When a large majority of people are dissatisfied with an existing norm, it seems obvious that they will change it. Often, however, this does not occur. We investigate how a time lag between individual support of a norm change and the change itself hinders such change, related to the critical mass of supporters needed to effectuate the change, and the (im)possibility of communicating about it. To isolate these factors, we utilize a laboratory experiment. As predicted, we find unambiguous effects of time lag on precluding norm change; a higher threshold for a critical mass does so as well. Communication facilitates choosing superior norms but it does not necessarily lead to norm change when the uncertainty on whether there will be a norm change in the future is high. Communication seems to help coordination on actions at the present but not the future. Hence, the uncertainty driven by time lag makes individuals choose the status quo, here the unpopular norm. PMID:25880200

  7. Cultural Norms and Nonverbal Communication: An Illustration

    ERIC Educational Resources Information Center

    Chang, Yanrong

    2015-01-01

    Nonverbal communication takes place in specific cultural contexts and is influenced by cultural norms. Cultural norms are "social rules for what certain types of people should and should not do" (Hall, 2005). Different cultures might have different norms for nonverbal behaviors in specific social, relational, and geographical contexts.…

  8. Longitudinal Relationships Among Perceived Injunctive and Descriptive Norms and Marijuana Use

    PubMed Central

    Napper, Lucy E.; Kenney, Shannon R.; Hummer, Justin F.; Fiorot, Sara; LaBrie, Joseph W.

    2016-01-01

    Objective: The current study uses longitudinal data to examine the relative influence of perceived descriptive and injunctive norms for proximal and distal referents on marijuana use. Method: Participants were 740 undergraduate students (67% female) who completed web-based surveys at two time points 12 months apart. Time 1 measures included reports of marijuana use, approval, perceived descriptive norms, and perceived injunctive norms for the typical student, close friends, and parents. At Time 2, students reported on their marijuana use. Results: Results of a path analysis suggest that, after we controlled for Time 1 marijuana use, greater perceived friend approval indirectly predicted Time 2 marijuana use as mediated by personal approval. Greater perceived parental approval was both indirectly and directly associated with greater marijuana use at follow-up. Perceived typical-student descriptive norms were neither directly nor indirectly related to Time 2 marijuana use. Conclusions: The findings support the role of proximal injunctive norms in predicting college student marijuana use up to 12 months later. The results indicate the potential importance of developing normative interventions that incorporate the social influences of proximal referents. PMID:27172578

  9. Fraction of exhaled nitric oxide (FeNO ) norms in healthy North African children 5-16 years old.

    PubMed

    Rouatbi, Sonia; Alqodwa, Ashraf; Ben Mdella, Samia; Ben Saad, Helmi

    2013-10-01

    (i) To identify factors that influence the FeNO values in healthy North African, Arab children aged 6-16 years; (ii) to test the applicability and reliability of the previously published FeNO norms; and (iii) if needed, to establish FeNO norms in this population, and to prospectively assess its reliability. This was a cross-sectional analytical study. A convenience sample of healthy Tunisian children, aged 6-16 years was recruited. First subjects have responded to two questionnaires, and then FeNO levels were measured by an online method with electrochemical analyzer (Medisoft, Sorinnes [Dinant], Belgium). Anthropometric and spirometric data were collected. Simple and a multiple linear regressions were determined. The 95% confidence interval (95% CI) and upper limit of normal (ULN) were defined. Two hundred eleven children (107 boys) were retained. Anthropometric data, gender, socioeconomic level, obesity or puberty status, and sports activity were not independent influencing variables. Total sample FeNO data appeared to be influenced only by maximum mid expiratory flow (l sec(-1) ; r(2)  = 0.0236, P = 0.0516). For boys, only 1st second forced expiratory volume (l) explains a slight (r(2)  = 0.0451) but significant FeNO variability (P = 0.0281). For girls, FeNO was not significantly correlated with any children determined data. For North African/Arab children, FeNO values were significantly lower than in other populations and the available published FeNO norms did not reliably predict FeNO in our population. The mean ± SD (95% CI ULN, minimum-maximum) of FeNO (ppb) for the total sample was 5.0 ± 2.9 (5.4, 1.0-17.0). For North African, Arab children of any age, any FeNO value greater than 17.0 ppb may be considered abnormal. Finally, in an additional group of children prospectively assessed, we found no child with a FeNO higher than 17.0 ppb. Our FeNO norms enrich the global repository of FeNO norms the pediatrician can use to choose

  10. Understanding multiple levels of norms about teen pregnancy and their relationships to teens' sexual behaviors.

    PubMed

    Mollborn, Stefanie; Domingue, Benjamin W; Boardman, Jason D

    2014-06-01

    Researchers seeking to understand teen sexual behaviors often turn to age norms, but they are difficult to measure quantitatively. Previous work has usually inferred norms from behavioral patterns or measured group-level norms at the individual level, ignoring multiple reference groups. Capitalizing on the multilevel design of the Add Health survey, we measure teen pregnancy norms perceived by teenagers, as well as average norms at the school and peer network levels. School norms predict boys' perceived norms, while peer network norms predict girls' perceived norms. Peer network and individually perceived norms against teen pregnancy independently and negatively predict teens' likelihood of sexual intercourse. Perceived norms against pregnancy predict increased likelihood of contraception among sexually experienced girls, but sexually experienced boys' contraceptive behavior is more complicated: When both the boy and his peers or school have stronger norms against teen pregnancy he is more likely to contracept, and in the absence of school or peer norms against pregnancy, boys who are embarrassed are less likely to contracept. We conclude that: (1) patterns of behavior cannot adequately operationalize teen pregnancy norms, (2) norms are not simply linked to behaviors through individual perceptions, and (3) norms at different levels can operate independently of each other, interactively, or in opposition. This evidence creates space for conceptualizations of agency, conflict, and change that can lead to progress in understanding age norms and sexual behaviors.

  11. Understanding multiple levels of norms about teen pregnancy and their relationships to teens’ sexual behaviors

    PubMed Central

    Mollborn, Stefanie; Domingue, Benjamin W.; Boardman, Jason D.

    2014-01-01

    Researchers seeking to understand teen sexual behaviors often turn to age norms, but they are difficult to measure quantitatively. Previous work has usually inferred norms from behavioral patterns or measured group-level norms at the individual level, ignoring multiple reference groups. Capitalizing on the multilevel design of the Add Health survey, we measure teen pregnancy norms perceived by teenagers, as well as average norms at the school and peer network levels. School norms predict boys’ perceived norms, while peer network norms predict girls’ perceived norms. Peer network and individually perceived norms against teen pregnancy independently and negatively predict teens’ likelihood of sexual intercourse. Perceived norms against pregnancy predict increased likelihood of contraception among sexually experienced girls, but sexually experienced boys’ contraceptive behavior is more complicated: When both the boy and his peers or school have stronger norms against teen pregnancy he is more likely to contracept, and in the absence of school or peer norms against pregnancy, boys who are embarrassed are less likely to contracept. We conclude that: (1) patterns of behavior cannot adequately operationalize teen pregnancy norms, (2) norms are not simply linked to behaviors through individual perceptions, and (3) norms at different levels can operate independently of each other, interactively, or in opposition. This evidence creates space for conceptualizations of agency, conflict, and change that can lead to progress in understanding age norms and sexual behaviors. PMID:25104920

  12. Potential environmental and regulatory implications of naturally occurring radioactive materials (NORM).

    PubMed

    Paschoa, A S

    1998-03-01

    The immense volume of naturally occurring radioactive materials (NORM) wastes produced annually by extracting industries throughout the world deserves to come to the attention of international and national environmental protection agencies and regulatory bodies. Although a great deal of work has been done in the fields of radiation protection and remedial actions concerning uranium and other mines, the need to dispose of diffuse NORM wastes will have environmental and regulatory implications that thus far are not fully appreciated. NORM wastes constitute, by and large, unwanted byproducts of industrial activities as diverse as thorium and uranium milling, niobium, tin and gold mining extraction, water treatment, and the production of oil, gas, phosphate fertilizer, coal fire and aluminum. The volumes of NORM wastes produced annually could reach levels so high that the existing low level radioactive waste (LLRW) facilities would be readily occupied by NORM if controlled disposal procedures were not adopted. On the other hand, NORM cannot just be ignored as being below radiological concern (BRC) or lower than exempt concentration levels (ECLs), because sometimes NORM concentrations reach levels as high as 1 x 10(3) kBq/kg for 226Ra, and not much less for 228Ra. Unfortunately, thus far there is not enough information available concerning NORM wastes in key industries, though the international scientific community has been concerned, for a long time now, with technologically enhanced natural radiation exposures (TENRE). This article is written with the intention of examining, to the extent possible, the potential environmental and regulatory implications of NORM wastes being produced in selected industries.

  13. The "is" and the "ought": How do perceived social norms influence safety behaviors at work?

    PubMed

    Fugas, Carla S; Meliá, José L; Silva, Silvia A

    2011-01-01

    Despite a widespread view that social norms have an important contextual influence on health attitudes and behaviors, the impact of normative influences on safety behaviors has received very little attention. The current study proposes that supervisors' and coworkers' descriptive and injunctive safety norms influence proactive and compliance safety behaviors. Longitudinal results from 132 workers in a passenger transportation company support the link between coworkers' descriptive safety norms (at Time 1) and proactive safety practices (at Time 2). Crystallization of supervisor' injunctive safety norms (at Time 2) moderated the effect of coworkers' descriptive safety norms (at Time 1) on self-reported proactive safety behavior (at Time 2). These findings emphasize the differences between supervisors' and coworkers' descriptive and injunctive norms as sources of social influence on compliance and proactive safety behavior.

  14. "Who Doesn't?"--The Impact of Descriptive Norms on Corruption.

    PubMed

    Köbis, Nils C; van Prooijen, Jan-Willem; Righetti, Francesca; Van Lange, Paul A M

    2015-01-01

    Corruption poses one of the major societal challenges of our time. Considerable advances have been made in understanding corruption on a macro level, yet the psychological antecedents of corrupt behavior remain largely unknown. In order to explain why some people engage in corruption while others do not, we explored the impact of descriptive social norms on corrupt behavior by using a novel behavioral measure of corruption. We conducted three studies to test whether perceived descriptive norms of corruption (i.e. the belief about the prevalence of corruption in a specific context) influence corrupt behavior. The results indicated that descriptive norms highly correlate with corrupt behavior--both when measured before (Study 1) or after (Study 2) the behavioral measure of corruption. Finally, we adopted an experimental design to investigate the causal effect of descriptive norms on corruption (Study 3). Corrupt behavior in the corruption game significantly drops when participants receive short anti-corruption descriptive norm primes prior to the game. These findings indicate that perceived descriptive norms can impact corrupt behavior and, possibly, could offer an explanation for inter-personal and inter-cultural variation in corrupt behavior in the real world. We discuss implications of these findings and draw avenues for future research.

  15. Norm Theory: Comparing Reality to Its Alternatives.

    ERIC Educational Resources Information Center

    Kahneman, Daniel; Miller, Dale T.

    1986-01-01

    A theory of norms and normality is applied to some phenomena of emotional responses, social judgment, and conversations about causes. Norm theory is applied in analyses of enhanced emotional response to events that have abnormal causes, of generation of prediction from observations of behavior, and of the role of norms. (Author/LMO)

  16. Spectral filtering of gradient for l2-norm frequency-domain elastic waveform inversion

    NASA Astrophysics Data System (ADS)

    Oh, Ju-Won; Min, Dong-Joo

    2013-05-01

    To enhance the robustness of the l2-norm elastic full-waveform inversion (FWI), we propose a denoise function that is incorporated into single-frequency gradients. Because field data are noisy and modelled data are noise-free, the denoise function is designed based on the ratio of modelled data to field data summed over shots and receivers. We first take the sums of the modelled data and field data over shots, then take the sums of the absolute values of the resultant modelled data and field data over the receivers. Due to the monochromatic property of wavefields at each frequency, signals in both modelled and field data tend to be cancelled out or maintained, whereas certain types of noise, particularly random noise, can be amplified in field data. As a result, the spectral distribution of the denoise function is inversely proportional to the ratio of noise to signal at each frequency, which helps prevent the noise-dominant gradients from contributing to model parameter updates. Numerical examples show that the spectral distribution of the denoise function resembles a frequency filter that is determined by the spectrum of the signal-to-noise (S/N) ratio during the inversion process, with little human intervention. The denoise function is applied to the elastic FWI of synthetic data, with three types of random noise generated by the modified version of the Marmousi-2 model: white, low-frequency and high-frequency random noises. Based on the spectrum of S/N ratios at each frequency, the denoise function mainly suppresses noise-dominant single-frequency gradients, which improves the inversion results at the cost of spatial resolution.

  17. An Inside Look at Homeless Youths’ Social Networks: Perceptions of Substance Use Norms1

    PubMed Central

    Melander, Lisa A.; Tyler, Kimberly A.; Schmitz, Rachel M.

    2016-01-01

    Substance use among homeless young people is a pervasive problem, and there have been many efforts to understand more about the dynamics of this health compromising behavior. The current study examined perceived substance use norms within homeless youths’ social networks utilizing in-depth interviews. The sample included 19 homeless individuals aged 16 to 21. Four elements of substance use within networks emerged: substance use choices, drug use safety issues, encouragement and/or discouragement, and appropriate situations in which substance use is condoned. These findings provide unique insight into the norms associated with drug and alcohol use within homeless youths’ social networks. PMID:26989340

  18. QSAR models for describing the toxicological effects of ILs against Staphylococcus aureus based on norm indexes.

    PubMed

    He, Wensi; Yan, Fangyou; Jia, Qingzhu; Xia, Shuqian; Wang, Qiang

    2018-03-01

    The hazardous potential of ionic liquids (ILs) is becoming an issue of great concern due to their important role in many industrial fields as green agents. The mathematical model for the toxicological effects of ILs is useful for the risk assessment and design of environmentally benign ILs. The objective of this work is to develop QSAR models to describe the minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of ILs against Staphylococcus aureus (S. aureus). A total of 169 and 101 ILs with MICs and MBCs, respectively, are used to obtain multiple linear regression models based on matrix norm indexes. The norm indexes used in this work are proposed by our research group and they are first applied to estimate the antibacterial toxicity of these ILs against S. aureus. These two models precisely and reliably calculated the IL toxicities with a square of correlation coefficient (R 2 ) of 0.919 and a standard error of estimate (SE) of 0.341 (in log unit of mM) for pMIC, and an R 2 of 0.913 and SE of 0.282 for pMBC. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Bundles of Norms About Teen Sex and Pregnancy.

    PubMed

    Mollborn, Stefanie; Sennott, Christie

    2015-09-01

    Teen pregnancy is a cultural battleground in struggles over morality, education, and family. At its heart are norms about teen sex, contraception, pregnancy, and abortion. Analyzing 57 interviews with college students, we found that "bundles" of related norms shaped the messages teens hear. Teens did not think their communities encouraged teen sex or pregnancy, but normative messages differed greatly, with either moral or practical rationalizations. Teens readily identified multiple norms intended to regulate teen sex, contraception, abortion, childbearing, and the sanctioning of teen parents. Beyond influencing teens' behavior, norms shaped teenagers' public portrayals and post hoc justifications of their behavior. Although norm bundles are complex to measure, participants could summarize them succinctly. These bundles and their conflicting behavioral prescriptions create space for human agency in negotiating normative pressures. The norm bundles concept has implications for teen pregnancy prevention policies and can help revitalize social norms for understanding health behaviors. © The Author(s) 2014.

  20. The malleability of injunctive norms among college students.

    PubMed

    Prince, Mark A; Carey, Kate B

    2010-11-01

    Alcohol use among college students has been associated with injunctive norms, which refer to the perceived acceptability of excessive drinking, and descriptive norms, which refer to perceptions of actual drinking. The purpose of this study was to examine the effect of a brief injunctive norms manipulation on both injunctive and descriptive norms about drinking alcohol and to explore differences in the malleability of norms across referent groups, sex, and gender role. Participants were 265 undergraduates (43% male, 70% freshmen) who completed a web-based survey for course credit. A randomly selected half was exposed to a page of information-based feedback about typical student injunctive norms. Relative to the control condition, the manipulation produced lower injunctive and descriptive norms related to typical students' drinking but no change in either type of norm related to close friends. Femininity was associated with less permissive normative beliefs about the acceptability of excessive drinking whereas masculinity was associated with elevated perceptions of peer drinking, but neither sex nor gender role moderated the manipulation effect. We conclude that perceptions of peer approval of drinking are malleable with a very brief information-based manipulation. Copyright 2010 Elsevier Ltd. All rights reserved.

  1. Longitudinal Relationship Between Drinking with Peers, Descriptive Norms, and Adolescent Alcohol Use

    PubMed Central

    Brooks-Russell, Ashley; Simons-Morton, Bruce; Haynie, Denise; Farhat, Tilda; Wang, Jing

    2014-01-01

    Descriptive norms are consistently found to predict adolescent alcohol use but less is known about the factors that predict descriptive norms. The objective of this study is to test if drinking with peers predicts later alcohol consumption and if this relationship is mediated by a change in the descriptive norms of peer alcohol use. Data are from a nationally representative cohort of high school students surveyed in the 10th and 11th grade (N=2,162). Structural equation modeling was used to test a mediation model of the relationship between drinking with peers (T1) on later alcohol use (T2) and mediation of the relationship by descriptive norms (T2). Descriptive norms significantly mediated the relationship between drinking with peers and alcohol use for both males and females with a somewhat larger effect for males compared to females. These results support a continued focus on the development and evaluation of interventions to alter descriptive norms of alcohol use. PMID:23564529

  2. Longitudinal relationship between drinking with peers, descriptive norms, and adolescent alcohol use.

    PubMed

    Brooks-Russell, Ashley; Simons-Morton, Bruce; Haynie, Denise; Farhat, Tilda; Wang, Jing

    2014-08-01

    Descriptive norms are consistently found to predict adolescent alcohol use but less is known about the factors that predict descriptive norms. The objective of this study is to test if drinking with peers predicts later alcohol consumption and if this relationship is mediated by a change in the descriptive norms of peer alcohol use. Data are from a nationally representative cohort of high school students surveyed in the 10th and 11th grade (N = 2,162). Structural equation modeling was used to test a mediation model of the relationship between drinking with peers (T1) on later alcohol use (T2) and mediation of the relationship by descriptive norms (T2). Descriptive norms significantly mediated the relationship between drinking with peers and alcohol use for both males and females with a somewhat larger effect for males compared to females. These results support a continued focus on the development and evaluation of interventions to alter descriptive norms of alcohol use.

  3. NWEA FAQ: RIT Scale Norms

    ERIC Educational Resources Information Center

    Northwest Evaluation Association, 2015

    2015-01-01

    Northwest Evaluation Association™ (NWEA™) conducts norming studies every several years to provide the best and most up-to-date information we can about student achievement and growth to better support educational decision-making. It is an important part of our commitment to our partners. The most recent NWEA norms were released in July 2015. Just…

  4. Point-spread function reconstruction in ground-based astronomy by l(1)-l(p) model.

    PubMed

    Chan, Raymond H; Yuan, Xiaoming; Zhang, Wenxing

    2012-11-01

    In ground-based astronomy, images of objects in outer space are acquired via ground-based telescopes. However, the imaging system is generally interfered by atmospheric turbulence, and hence images so acquired are blurred with unknown point-spread function (PSF). To restore the observed images, the wavefront of light at the telescope's aperture is utilized to derive the PSF. A model with the Tikhonov regularization has been proposed to find the high-resolution phase gradients by solving a least-squares system. Here we propose the l(1)-l(p) (p=1, 2) model for reconstructing the phase gradients. This model can provide sharper edges in the gradients while removing noise. The minimization models can easily be solved by the Douglas-Rachford alternating direction method of a multiplier, and the convergence rate is readily established. Numerical results are given to illustrate that the model can give better phase gradients and hence a more accurate PSF. As a result, the restored images are much more accurate when compared to the traditional Tikhonov regularization model.

  5. Social influence in the theory of planned behaviour: the role of descriptive, injunctive, and in-group norms.

    PubMed

    White, Katherine M; Smith, Joanne R; Terry, Deborah J; Greenslade, Jaimi H; McKimmie, Blake M

    2009-03-01

    The present research investigated three approaches to the role of norms in the theory of planned behaviour (TPB). Two studies examined the proposed predictors of intentions to engage in household recycling (Studies 1 and 2) and reported recycling behaviour (Study 1). Study 1 tested the impact of descriptive and injunctive norms (personal and social) and the moderating role of self-monitoring on norm-intention relations. Study 2 examined the role of group norms and group identification and the moderating role of collective self on norm-intention relations. Both studies demonstrated support for the TPB and the inclusion of additional normative variables: attitudes; perceived behavioural control; descriptive; and personal injunctive norms (but not social injunctive norm) emerged as significant independent predictors of intentions. There was no evidence that the impact of norms on intentions varied as a function of the dispositional variables of self-monitoring (Study 1) or the collective self (Study 2). There was support, however, for the social identity approach to attitude-behaviour relations in that group norms predicted recycling intentions, particularly for individuals who identified strongly with the group. The results of these two studies highlight the critical role of social influence processes within the TPB and the attitude-behaviour context.

  6. Inferring the Minimal Genome of Mesoplasma florum by Comparative Genomics and Transposon Mutagenesis.

    PubMed

    Baby, Vincent; Lachance, Jean-Christophe; Gagnon, Jules; Lucier, Jean-François; Matteau, Dominick; Knight, Tom; Rodrigue, Sébastien

    2018-01-01

    The creation and comparison of minimal genomes will help better define the most fundamental mechanisms supporting life. Mesoplasma florum is a near-minimal, fast-growing, nonpathogenic bacterium potentially amenable to genome reduction efforts. In a comparative genomic study of 13 M. florum strains, including 11 newly sequenced genomes, we have identified the core genome and open pangenome of this species. Our results show that all of the strains have approximately 80% of their gene content in common. Of the remaining 20%, 17% of the genes were found in multiple strains and 3% were unique to any given strain. On the basis of random transposon mutagenesis, we also estimated that ~290 out of 720 genes are essential for M. florum L1 in rich medium. We next evaluated different genome reduction scenarios for M. florum L1 by using gene conservation and essentiality data, as well as comparisons with the first working approximation of a minimal organism, Mycoplasma mycoides JCVI-syn3.0. Our results suggest that 409 of the 473 M. mycoides JCVI-syn3.0 genes have orthologs in M. florum L1. Conversely, 57 putatively essential M. florum L1 genes have no homolog in M. mycoides JCVI-syn3.0. This suggests differences in minimal genome compositions, even for these evolutionarily closely related bacteria. IMPORTANCE The last years have witnessed the development of whole-genome cloning and transplantation methods and the complete synthesis of entire chromosomes. Recently, the first minimal cell, Mycoplasma mycoides JCVI-syn3.0, was created. Despite these milestone achievements, several questions remain to be answered. For example, is the composition of minimal genomes virtually identical in phylogenetically related species? On the basis of comparative genomics and transposon mutagenesis, we investigated this question by using an alternative model, Mesoplasma florum, that is also amenable to genome reduction efforts. Our results suggest that the creation of additional minimal

  7. EEG Arousal Norms by Age

    PubMed Central

    Bonnet, Michael H.; Arand, Donna L.

    2007-01-01

    Study Objectives: Brief arousals have been systematically scored during sleep for more than 20 years. Despite significant knowledge concerning the importance of arousals for the sleep process in normal subjects and patients, comprehensive age norms have not been published. Methods: Seventy-six normal subjects (40 men) without sleep apnea or periodic limb movements of sleep, aged 18 to 70 years, slept in the sleep laboratory for 1 or more nights. Sleep and arousal data were scored by the same scorer for the first night (comparable to clinical polysomnograms) and summarized by age decade. Results: There were no statistically significant differences for sex or interaction of sex by age (p > .5 for both). The mean arousal index increased as a function of age. Newman-Keuls comparisons (.05) showed arousal index in the 18- to 20-year and 21- to 30-year age groups to be significantly less than the arousal index in the other 4 age groups. Arousal index in the 31-to 40-year and 41-to 50-year groups was significantly less than the arousal index in the older groups. The arousal index was significantly negatively correlated with total sleep time and all sleep stages (positive correlation with stage 1 and wake). Conclusions: Brief arousals are an integral component of the sleep process. They increase with other electroencephalographic markers as a function of age. They are highly correlated with traditional sleep-stage amounts and are related to major demographic variables. Age-related norms may make identification of pathologic arousal easier. Citations: Bonnet M; Arand D. EEG Arousal Norms by Age. J Clin Sleep Med 2007;3(3):271–274 PMID:17561594

  8. Longitudinal relationships between individual and class norms supporting dating violence and perpetration of dating violence.

    PubMed

    Taylor, Katherine A; Sullivan, Terri N; Farrell, Albert D

    2015-03-01

    Dating violence is commonly perpetrated in adolescence, making it imperative to understand risk factors in order to inform prevention efforts. Although individual norms supporting dating violence are strongly related to its perpetration, few studies have examined their longitudinal impact. Moreover, the influence of class norms (i.e., norms for students in the same grade, cohort, and school) supporting dating violence on perpetration has rarely been studied. The current study examined longitudinal relationships between individual and class norms supporting dating violence and perpetration of physical and psychological dating violence. Participants were two cohorts of sixth graders from 37 schools who were in dating relationships at Wave 1 and 6 months later at Wave 2 (N = 2,022; 43% female; 52% African American, 21% Latino/a, 20% White, and 7% other). The analyses used a multilevel approach, with students represented at Level 1 and classes (n = 74) at Level 2. The models tested direct effects of Wave 1 individual and class norms supporting dating violence on subsequent changes in perpetration of dating violence at Wave 2 and the extent to which gender moderated these relationships. The findings indicated that greater individual norms supporting male dating violence predicted greater change in perpetration of physical and psychological dating violence and greater individual norms supporting female dating violence predicted greater change in perpetration of psychological dating violence. Greater class norms supporting male dating violence predicted greater change in perpetration of physical dating violence; whereas greater class norms supporting female dating violence predicted less change in perpetration of physical dating violence. These findings highlight the need to address norms in early adolescence.

  9. Diagnosis and prevention of norm at Eugene Island 341-A

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shuler, P.J.; Baudoin, D.A.; Weintritt, D.J.

    1995-12-01

    We conducted a field study at Eugene Island 341-A to develop guidelines for the cost-effective prevention of NORM (Naturally Occurring Radioactive Materials). The specific objectives of this study are to: determine the root cause of the NORM problem at this facility, using a wide variety of diagnostic techniques. consider available engineering options to prevent NORM from forming. determine the most cost-effective engineering solution. An overall objective is to Generalize the results and diagnostic techniques developed for Eugene Island 341-A to other production facilities, especially in the Gulf of Mexico. This study shows that the NORM problem at Eugene Island 34more » 1-A stems from mixing incompatible produced waters at the surface. Wells completed in Sand Block A have a water with relatively high barium concentration, those in Sand Block B and C are high in sulfate, When these waters mix (starting in the production headers), barium sulfate forms. Radium that is present in the produced brines co-precipitates with the barium, thus creating a radioactive barium sulfate scale deposit (NORM). The barium sulfate (and hence NORM) can be prevented by improving the current scale inhibition program. Keys to an effective program are the continual, reliable injection of an appropriate scale inhibitor at an effective dosage, ahead of the point where scaling conditions begin.« less

  10. Social anxiety and social norms in individualistic and collectivistic countries

    PubMed Central

    Schreier, Sina-Simone; Heinrichs, Nina; Alden, Lynn; Rapee, Ronald M.; Hofmann, Stefan G.; Chen, Junwen; Ja Oh, Kyung; Bögels, Susan

    2010-01-01

    Background Social anxiety is assumed to be related to cultural norms across countries. Heinrichs and colleagues [1] compared individualistic and collectivistic countries and found higher social anxiety and more positive attitudes toward socially avoidant behaviors in collectivistic than in individualistic countries. However, the authors failed to include Latin American countries in the collectivistic group. Methods To provide support for these earlier results within an extended sample of collectivistic countries, 478 undergraduate students from individualistic countries were compared with 388 undergraduate students from collectivistic countries (including East Asian and Latin American) via self report of social anxiety and social vignettes assessing social norms. Results As expected, the results of Heinrichs and colleagues [1] were replicated for the individualistic and Asian countries but not for Latin American countries. Latin American countries displayed the lowest social anxiety levels, whereas the collectivistic East Asian group displayed the highest. Conclusions These findings indicate that while culture-mediated social norms affect social anxiety and might help to shed light on the etiology of social anxiety disorder, the dimension of individualism-collectivism may not fully capture the relevant norms. PMID:21049538

  11. Anti-PD-L1 Treatment Induced Central Diabetes Insipidus.

    PubMed

    Zhao, Chen; Tella, Sri Harsha; Del Rivero, Jaydira; Kommalapati, Anuhya; Ebenuwa, Ifechukwude; Gulley, James; Strauss, Julius; Brownell, Isaac

    2018-02-01

    Immune checkpoint inhibitors, including anti-programmed cell death protein 1 (PD-1), anti-programmed cell death protein ligand 1 (PD-L1), and anti-cytotoxic T-lymphocyte antigen 4 (anti-CTLA4) monoclonal antibodies, have been widely used in cancer treatment. They are known to cause immune-related adverse events (irAEs), which resemble autoimmune diseases. Anterior pituitary hypophysitis with secondary hypopituitarism is a frequently reported irAE, especially in patients receiving anti-CTLA4 treatment. In contrast, posterior pituitary involvement, such as central diabetes insipidus (DI), is relatively rare and is unreported in patients undergoing PD-1/PD-L1 blockade. We describe a case of a 73-year-old man with Merkel cell carcinoma who received the anti-PD-L1 monoclonal antibody avelumab and achieved partial response. The patient developed nocturia, polydipsia, and polyuria 3 months after starting avelumab. Further laboratory testing revealed central DI. Avelumab was held and he received desmopressin for the management of central DI. Within 6 weeks after discontinuation of avelumab, the patient's symptoms resolved and he was eventually taken off desmopressin. The patient remained off avelumab and there were no signs or symptoms of DI 2 months after the discontinuation of desmopressin. To our knowledge, this is the first report of central DI associated with anti-PD-L1 immunotherapy. The patient's endocrinopathy was successfully managed by holding treatment with the immune checkpoint inhibitor. This case highlights the importance of early screening and appropriate management of hormonal irAEs in subjects undergoing treatment with immune checkpoint inhibitors to minimize morbidity and mortality. Copyright © 2017 Endocrine Society

  12. Ascorbic Acid Metabolism in Pea Seedlings. A Comparison of d-Glucosone, l-Sorbosone, and l-Galactono-1,4-Lactone as Ascorbate Precursors1

    PubMed Central

    Pallanca, Jane E.; Smirnoff, Nicholas

    1999-01-01

    l-Ascorbic acid (AsA) accumulates in pea (Pisum sativum L.) seedlings during germination, with the most rapid phase of accumulation coinciding with radicle emergence. Monodehydroascorbate reductase and dehydroascorbic acid reductase were active in the embryonic axes before AsA accumulation started, whereas AsA oxidase and AsA peroxidase activities increased in parallel with AsA. Excised embryonic axes were used to investigate the osone pathway of AsA biosynthesis, in which d-glucosone and l-sorbosone are the proposed intermediates. [U-14C]Glucosone was incorporated into AsA and inhibited the incorporation of [U-14C]glucose (Glc) into AsA. A higher d-glucosone concentration (5 mm) inhibited AsA accumulation. l-Sorbosone did not affect AsA pool size but caused a small inhibition in the incorporation of [U-14C]Glc into AsA. Oxidase and dehydrogenase activities capable of converting Glc or Glc-6-phosphate to glucosone were not detected in embryonic axis extracts. The osones are therefore unlikely to be physiological intermediates of AsA biosynthesis. l-Galactono-1,4-lactone, recently proposed as the AsA precursor (G.L. Wheeler, M.A. Jones, N. Smirnoff [1998] Nature 393: 365–369), was readily converted to AsA by pea embryonic axes. Although l-galactono-1,4-lactone did not inhibit [14C]Glc incorporation into AsA, this does not mean that it is not a precursor, because competition between endogenous and exogenous pools was minimized by its very small pool size and rapid metabolism. PMID:10364396

  13. Minority acculturation and peer rejection: Costs of acculturation misfit with peer-group norms.

    PubMed

    Celeste, Laura; Meeussen, Loes; Verschueren, Karine; Phalet, Karen

    2016-09-01

    How do minority adolescents' personal acculturation preferences and peer norms of acculturation affect their social inclusion in school? Turkish and Moroccan minority adolescents (N = 681) reported their preferences for heritage culture maintenance, mainstream culture adoption, and their experiences of peer rejection as a key indicator of adjustment problems. Additionally, we aggregated peer acculturation norms of maintenance and adoption within ethnically diverse classrooms (N = 230 in 50 Belgian schools), distinguishing between co-ethnic (Turkish or Moroccan classmates only, N = 681) and cross-ethnic norms (also including N = 1,930 other classmates). Cross-ethnic peer-group norms (of adoption and maintenance) and co-ethnic norms (of maintenance, marginally) predicted minority experiences of peer rejection (controlling for ethnic composition). Moreover, misfit of minorities' own acculturation preferences with both cross-ethnic and co-ethnic peer-group norms was harmful. When cross-ethnic norms stressed adoption, 'integrationist' minority youth - who combined culture adoption with maintenance - experienced most peer rejection. Yet, when co-ethnic peers stressed maintenance, 'assimilationist' minority youth experienced most rejection. In conclusion, acculturation misfit with peer-group norms is a risk factor for minority inclusion in ethnically diverse environments. © 2016 The British Psychological Society.

  14. Monoclonal Antibody L1Mab-13 Detected Human PD-L1 in Lung Cancers.

    PubMed

    Yamada, Shinji; Itai, Shunsuke; Nakamura, Takuro; Yanaka, Miyuki; Chang, Yao-Wen; Suzuki, Hiroyoshi; Kaneko, Mika K; Kato, Yukinari

    2018-04-01

    Programmed cell death ligand-1 (PD-L1) is a type I transmembrane glycoprotein expressed on antigen-presenting cells. It is also expressed in several tumor cells such as melanoma and lung cancer cells. A strong correlation has been reported between human PD-L1 (hPD-L1) expression in tumor cells and negative prognosis in cancer patients. Here, a novel anti-hPD-L1 monoclonal antibody (mAb) L 1 Mab-13 (IgG 1 , kappa) was produced using a cell-based immunization and screening (CBIS) method. We investigated hPD-L1 expression in lung cancer using flow cytometry, Western blot, and immunohistochemical analyses. L 1 Mab-13 specifically reacted hPD-L1 of hPD-L1-overexpressed Chinese hamster ovary (CHO)-K1 cells and endogenous hPD-L1 of KMST-6 (human fibroblast) in flow cytometry and Western blot. Furthermore, L 1 Mab-13 reacted with lung cancer cell lines (EBC-1, Lu65, and Lu99) in flow cytometry and stained lung cancer tissues in a membrane-staining pattern in immunohistochemical analysis. These results indicate that a novel anti-hPD-L1 mAb, L 1 Mab-13, is very useful for detecting hPD-L1 of lung cancers in flow cytometry, Western blot, and immunohistochemical analyses.

  15. Polyphenol oxidase activity from three sicilian artichoke [ Cynara cardunculus L. Var. scolymus L. (Fiori)] cultivars: studies and technological application on minimally processed production.

    PubMed

    Todaro, Aldo; Peluso, Orazio; Catalano, Anna Eghle; Mauromicale, Giovanni; Spagna, Giovanni

    2010-02-10

    Several papers helped with the development of more methods to control browning, or study thermal polyphenol oxidase (PPO) inactivation, but did not provide any solutions to technological process problems and food process improvement. Artichokes [ Cynara cardunculus L. var. scolymus L. (Fiori)] are susceptible to browning; this alteration could affect and reduce the suitability for its use, fresh or processed. Within this study, the catecholase and cresolase activities of PPO from three different Sicilian artichokes cultivar were characterized with regard to substrate specificity and enzyme kinetics, optimum pH and temperature, temperature and pH stability, and inhibitor test; all of the results were used for technological purposes, particularly to optimize minimally processed productions (ready-to-eat and cook-chilled artichokes).

  16. Collective action and the evolution of social norm internalization

    PubMed Central

    Gavrilets, Sergey; Richerson, Peter J.

    2017-01-01

    Human behavior is strongly affected by culturally transmitted norms and values. Certain norms are internalized (i.e., acting according to a norm becomes an end in itself rather than merely a tool in achieving certain goals or avoiding social sanctions). Humans’ capacity to internalize norms likely evolved in our ancestors to simplify solving certain challenges—including social ones. Here we study theoretically the evolutionary origins of the capacity to internalize norms. In our models, individuals can choose to participate in collective actions as well as punish free riders. In making their decisions, individuals attempt to maximize a utility function in which normative values are initially irrelevant but play an increasingly important role if the ability to internalize norms emerges. Using agent-based simulations, we show that norm internalization evolves under a wide range of conditions so that cooperation becomes “instinctive.” Norm internalization evolves much more easily and has much larger effects on behavior if groups promote peer punishment of free riders. Promoting only participation in collective actions is not effective. Typically, intermediate levels of norm internalization are most frequent but there are also cases with relatively small frequencies of “oversocialized” individuals willing to make extreme sacrifices for their groups no matter material costs, as well as “undersocialized” individuals completely immune to social norms. Evolving the ability to internalize norms was likely a crucial step on the path to large-scale human cooperation. PMID:28533363

  17. Collective action and the evolution of social norm internalization.

    PubMed

    Gavrilets, Sergey; Richerson, Peter J

    2017-06-06

    Human behavior is strongly affected by culturally transmitted norms and values. Certain norms are internalized (i.e., acting according to a norm becomes an end in itself rather than merely a tool in achieving certain goals or avoiding social sanctions). Humans' capacity to internalize norms likely evolved in our ancestors to simplify solving certain challenges-including social ones. Here we study theoretically the evolutionary origins of the capacity to internalize norms. In our models, individuals can choose to participate in collective actions as well as punish free riders. In making their decisions, individuals attempt to maximize a utility function in which normative values are initially irrelevant but play an increasingly important role if the ability to internalize norms emerges. Using agent-based simulations, we show that norm internalization evolves under a wide range of conditions so that cooperation becomes "instinctive." Norm internalization evolves much more easily and has much larger effects on behavior if groups promote peer punishment of free riders. Promoting only participation in collective actions is not effective. Typically, intermediate levels of norm internalization are most frequent but there are also cases with relatively small frequencies of "oversocialized" individuals willing to make extreme sacrifices for their groups no matter material costs, as well as "undersocialized" individuals completely immune to social norms. Evolving the ability to internalize norms was likely a crucial step on the path to large-scale human cooperation.

  18. OPERATOR NORM INEQUALITIES BETWEEN TENSOR UNFOLDINGS ON THE PARTITION LATTICE

    PubMed Central

    Wang, Miaoyan; Duc, Khanh Dao; Fischer, Jonathan; Song, Yun S.

    2017-01-01

    Interest in higher-order tensors has recently surged in data-intensive fields, with a wide range of applications including image processing, blind source separation, community detection, and feature extraction. A common paradigm in tensor-related algorithms advocates unfolding (or flattening) the tensor into a matrix and applying classical methods developed for matrices. Despite the popularity of such techniques, how the functional properties of a tensor changes upon unfolding is currently not well understood. In contrast to the body of existing work which has focused almost exclusively on matricizations, we here consider all possible unfoldings of an order-k tensor, which are in one-to-one correspondence with the set of partitions of {1, …, k}. We derive general inequalities between the lp-norms of arbitrary unfoldings defined on the partition lattice. In particular, we demonstrate how the spectral norm (p = 2) of a tensor is bounded by that of its unfoldings, and obtain an improved upper bound on the ratio of the Frobenius norm to the spectral norm of an arbitrary tensor. For specially-structured tensors satisfying a generalized definition of orthogonal decomposability, we prove that the spectral norm remains invariant under specific subsets of unfolding operations. PMID:28286347

  19. Control of browning of minimally processed mangoes subjected to ultraviolet radiation pulses.

    PubMed

    de Sousa, Aline Ellen Duarte; Fonseca, Kelem Silva; da Silva Gomes, Wilny Karen; Monteiro da Silva, Ana Priscila; de Oliveira Silva, Ebenézer; Puschmann, Rolf

    2017-01-01

    The pulsed ultraviolet radiation (UV P ) has been used as an alternative strategy for the control of microorganisms in food. However, its application causes the browning of minimally processed fruits and vegetables. In order to control the browning of the 'Tommy Atkins' minimally processed mango and treated with UV P (5.7 J cm -2 ) it was used 1-methylcyclopropene (1-MCP) (0.5 μL L -1 ), an ethylene action blocker in separate stages, comprising five treatments: control, UV P (U), 1-MCP + UV P (M + U), UV P  + 1-MCP (U + M) e 1-MCP + UV P  + 1-MCP (M + U + M). At the 1st, 7th and 14th days of storage at 12 °C, we evaluated the color (L* and b*), electrolyte leakage, polyphenol oxidase, total extractable polyphenols, vitamin C and total antioxidant activity. The 1-MCP, when applied before UV P , prevented the loss of vitamin C and when applied in a double dose, retained the yellow color (b*) of the cubes. However, the 1-MCP reduced lightness (L*) of independent mango cubes whatever applied before and/or after the UV P . Thus, the application of 1-MCP did not control, but intensified the browning of minimally processed mangoes irradiated with UV P .

  20. LQS_INVERSION v. 1.0

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Weiss, Chester J

    FORTRAN90 codes for inversion of electrostatic geophysical data in terms of three subsurface parameters in a single-well, oilfield environment: the linear charge density of the steel well casing (L), the point charge associated with an induced fracture filled with a conductive contrast agent (Q) and the location of said fracture (s). Theory is described in detail in Weiss et al. (Geophysics, 2016). Inversion strategy is to loop over candidate fracture locations, and at each one minimize the squared Cartesian norm of the data misfit to arrive at L and Q. Solution method is to construct the 2x2 linear system ofmore » normal equations and compute L and Q algebraically. Practical Application: Oilfield environments where observed electrostatic geophysical data can reasonably be assumed by a simple L-Q-s model. This may include hydrofracking operations, as postulated in Weiss et al. (2016), but no field validation examples have so far been provided.« less

  1. GhL1L1 affects cell fate specification by regulating GhPIN1-mediated auxin distribution.

    PubMed

    Xu, Jiao; Yang, Xiyan; Li, Baoqi; Chen, Lin; Min, Ling; Zhang, Xianlong

    2018-05-13

    Auxin is as an efficient initiator and regulator of cell fate during somatic embryogenesis (SE), but the molecular mechanisms and regulating networks of this process are not well understood. In this report, we analysed SE process induced by Leafy cotyledon1-like 1 (GhL1L1), a NF-YB subfamily gene specifically expressed in embryonic tissues in cotton. We also identified the target gene of GhL1L1, and its role in auxin distribution and cell fate specification during embryonic development was analysed. Overexpression of GhL1L1 accelerated embryonic cell formation, associated with an increased concentration of IAA in embryogenic calluses (ECs) and in the shoot apical meristem (SAM), corresponding to altered expression of the auxin transport gene GhPIN1. By contrast, GhL1L1-deficient explants showed retarded embryonic cell formation, and the concentration of IAA was decreased in GhL1L1-deficient ECs. Disruption of auxin distribution accelerated the specification of embryonic cell fate together with regulation of GhPIN1. Furthermore, we showed that PHOSPHATASE 2AA2 (GhPP2AA2) was activated by GhL1L1 through targeting the G-box of its promoter, hence regulating the activity of GhPIN1 protein. Our results indicate that GhL1L1 functions as a key regulator in auxin distribution to regulate cell fate specification in cotton and contribute to the understanding of the complex process of SE in plant species. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  2. Sparse deconvolution for the large-scale ill-posed inverse problem of impact force reconstruction

    NASA Astrophysics Data System (ADS)

    Qiao, Baijie; Zhang, Xingwu; Gao, Jiawei; Liu, Ruonan; Chen, Xuefeng

    2017-01-01

    Most previous regularization methods for solving the inverse problem of force reconstruction are to minimize the l2-norm of the desired force. However, these traditional regularization methods such as Tikhonov regularization and truncated singular value decomposition, commonly fail to solve the large-scale ill-posed inverse problem in moderate computational cost. In this paper, taking into account the sparse characteristic of impact force, the idea of sparse deconvolution is first introduced to the field of impact force reconstruction and a general sparse deconvolution model of impact force is constructed. Second, a novel impact force reconstruction method based on the primal-dual interior point method (PDIPM) is proposed to solve such a large-scale sparse deconvolution model, where minimizing the l2-norm is replaced by minimizing the l1-norm. Meanwhile, the preconditioned conjugate gradient algorithm is used to compute the search direction of PDIPM with high computational efficiency. Finally, two experiments including the small-scale or medium-scale single impact force reconstruction and the relatively large-scale consecutive impact force reconstruction are conducted on a composite wind turbine blade and a shell structure to illustrate the advantage of PDIPM. Compared with Tikhonov regularization, PDIPM is more efficient, accurate and robust whether in the single impact force reconstruction or in the consecutive impact force reconstruction.

  3. A room with a viewpoint revisited: descriptive norms and hotel guests' towel reuse behavior.

    PubMed

    Bohner, Gerd; Schlüter, Lena E

    2014-01-01

    Field experiments on descriptive norms as a means to increase hotel guests' towel reuse [1] were replicated and extended. In two hotels in Germany (Study 1: N = 724; Study 2: N = 204), descriptive norm messages suggesting that 75% of guests had reused their towels, or a standard message appealing to environmental concerns, were placed in guests' bathrooms. Descriptive norm messages varied in terms of proximity of the reference group ("hotel guests" vs. "guests in this room") and temporal proximity (currently vs. two years previous). Reuse of towels was unobtrusively recorded. Results showed that reuse rates were high overall and that both standard and descriptive norm messages increased reuse rates compared to a no-message baseline. However, descriptive norm messages were not more effective than the standard message, and effects of proximity were inconsistent across studies. Discussion addresses cultural and conceptual issues in comparing the present findings with previous ones.

  4. Reliance on God, prayer, and religion reduces influence of perceived norms on drinking.

    PubMed

    Neighbors, Clayton; Brown, Garrett A; Dibello, Angelo M; Rodriguez, Lindsey M; Foster, Dawn W

    2013-05-01

    Previous research has shown that perceived social norms are among the strongest predictors of drinking among young adults. Research has also consistently found religiousness to be protective against risk and negative health behaviors. The present research evaluates the extent to which reliance on God, prayer, and religion moderates the association between perceived social norms and drinking. Participants (n = 1,124 undergraduate students) completed a cross-sectional survey online, which included measures of perceived norms, religious values, and drinking. Perceived norms were assessed by asking participants their perceptions of typical student drinking. Drinking outcomes included drinks per week, drinking frequency, and typical quantity consumed. Regression analyses indicated that religiousness and perceived norms had significant unique associations in opposite directions for all three drinking outcomes. Significant interactions were evident between religiousness and perceived norms in predicting drinks per week, frequency, and typical quantity. In each case, the interactions indicated weaker associations between norms and drinking among those who assigned greater importance to religiousness. The extent of the relationship between perceived social norms and drinking was buffered by the degree to which students identified with religiousness. A growing body of literature has shown interventions including personalized feedback regarding social norms to be an effective strategy in reducing drinking among college students. The present research suggests that incorporating religious or spiritual values into student interventions may be a promising direction to pursue.

  5. ESTIMATION OF EXPOSURE DOSES FOR THE SAFE MANAGEMENT OF NORM WASTE DISPOSAL.

    PubMed

    Jeong, Jongtae; Ko, Nak Yul; Cho, Dong-Keun; Baik, Min Hoon; Yoon, Ki-Hoon

    2018-03-16

    Naturally occurring radioactive materials (NORM) wastes with different radiological characteristics are generated in several industries. The appropriate options for NORM waste management including disposal options should be discussed and established based on the act and regulation guidelines. Several studies calculated the exposure dose and mass of NORM waste to be disposed in landfill site by considering the activity concentration level and exposure dose. In 2012, the Korean government promulgated an act on the safety control of NORM around living environments to protect human health and the environment. For the successful implementation of this act, we suggest a reference design for a landfill for the disposal of NORM waste. Based on this reference landfill, we estimate the maximum exposure doses and the relative impact of each pathway to exposure dose for three scenarios: a reference scenario, an ingestion pathway exclusion scenario, and a low leach rate scenario. Also, we estimate the possible quantity of NORM waste disposal into a landfill as a function of the activity concentration level of U series, Th series and 40K and two kinds of exposure dose levels, 1 and 0.3 mSv/y. The results of this study can be used to support the establishment of technical bases of the management strategy for the safe disposal of NORM waste.

  6. Mutations M287L and Q266I in the Glycine Receptor α1 Subunit Change Sensitivity to Volatile Anesthetics in Oocytes and Neurons, but Not the Minimal Alveolar Concentration in Knockin Mice

    PubMed Central

    Borghese, Cecilia M.; Xiong, Wei; Oh, S. Irene; Ho, Angel; Mihic, S. John; Zhang, Li; Lovinger, David M.; Homanics, Gregg E.; Eger, Edmond I; Harris, R. Adron

    2012-01-01

    Background Volatile anesthetics (VAs) alter the function of key central nervous system proteins but it is not clear which, if any, of these targets mediates the immobility produced by VAs in the face of noxious stimulation. A leading candidate is the glycine receptor, a ligand-gated ion channel important for spinal physiology. VAs variously enhance such function, and blockade of spinal GlyRs with strychnine affects the minimal alveolar concentration (an anesthetic EC50) in proportion to the degree of enhancement. Methods We produced single amino acid mutations into the glycine receptorα1 subunit that increased (M287L, third transmembrane region) or decreased (Q266I, second transmembrane region) sensitivity to isoflurane in recombinant receptors, and introduced such receptors into mice. The resulting knockin mice presented impaired glycinergic transmission, but heterozygous animals survived to adulthood, and we determined the effect of isoflurane on glycine-evoked responses of brain stem neurons from the knockin mice, and the minimal alveolar concentration for isoflurane and other VAs in the immature and mature knockin mice. Results Studies of glycine-evoked currents in brain stem neurons from knock-in mice confirmed the changes seen with recombinant receptors. No increases in the minimal alveolar concentration were found in knockin mice, but the minimal alveolar concentration for isoflurane and enflurane (but not halothane) decreased in 2-week-old Q266I mice. This change is opposite to the one expected for a mutation that decreases the sensitivity to volatile anesthetics. Conclusion Taken together, these results indicate that glycine receptors containing the α1 subunit are not likely to be crucial for the action of isoflurane and other VAs. PMID:22885675

  7. Low thrust spacecraft transfers optimization method with the stepwise control structure in the Earth-Moon system in terms of the L1-L2 transfer

    NASA Astrophysics Data System (ADS)

    Fain, M. K.; Starinova, O. L.

    2016-04-01

    The paper outlines the method for determination of the locally optimal stepwise control structure in the problem of the low thrust spacecraft transfer optimization in the Earth-Moon system, including the L1-L2 transfer. The total flight time as an optimization criterion is considered. The optimal control programs were obtained by using the Pontryagin's maximum principle. As a result of optimization, optimal control programs, corresponding trajectories, and minimal total flight times were determined.

  8. A Call for a New National Norming Methodology.

    ERIC Educational Resources Information Center

    Ligon, Glynn; Mangino, Evangelina

    Issues related to achieving adequate national norms are reviewed, and a new methodology is proposed that would work to provide a true measure of national achievement levels on an annual basis and would enable reporting results in current-year norms. Statistical methodology and technology could combine to create a national norming process that…

  9. A Room with a Viewpoint Revisited: Descriptive Norms and Hotel Guests' Towel Reuse Behavior

    PubMed Central

    Bohner, Gerd; Schlüter, Lena E.

    2014-01-01

    Field experiments on descriptive norms as a means to increase hotel guests' towel reuse [1] were replicated and extended. In two hotels in Germany (Study 1: N = 724; Study 2: N = 204), descriptive norm messages suggesting that 75% of guests had reused their towels, or a standard message appealing to environmental concerns, were placed in guests' bathrooms. Descriptive norm messages varied in terms of proximity of the reference group (“hotel guests” vs. “guests in this room”) and temporal proximity (currently vs. two years previous). Reuse of towels was unobtrusively recorded. Results showed that reuse rates were high overall and that both standard and descriptive norm messages increased reuse rates compared to a no-message baseline. However, descriptive norm messages were not more effective than the standard message, and effects of proximity were inconsistent across studies. Discussion addresses cultural and conceptual issues in comparing the present findings with previous ones. PMID:25084348

  10. Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab.

    PubMed

    Lee, Hyun Tae; Lee, Ju Yeon; Lim, Heejin; Lee, Sang Hyung; Moon, Yu Jeong; Pyo, Hyo Jeong; Ryu, Seong Eon; Shin, Woori; Heo, Yong-Seok

    2017-07-17

    In 2016 and 2017, monoclonal antibodies targeting PD-L1, including atezolizumab, durvalumab, and avelumab, were approved by the FDA for the treatment of multiple advanced cancers. And many other anti-PD-L1 antibodies are under clinical trials. Recently, the crystal structures of PD-L1 in complex with BMS-936559 and avelumab have been determined, revealing details of the antigen-antibody interactions. However, it is still unknown how atezolizumab and durvalumab specifically recognize PD-L1, although this is important for investigating novel binding sites on PD-L1 targeted by other therapeutic antibodies for the design and improvement of anti-PD-L1 agents. Here, we report the crystal structures of PD-L1 in complex with atezolizumab and durvalumab to elucidate the precise epitopes involved and the structural basis for PD-1/PD-L1 blockade by these antibodies. A comprehensive comparison of PD-L1 interactions with anti-PD-L1 antibodies provides a better understanding of the mechanism of PD-L1 blockade as well as new insights into the rational design of improved anti-PD-L1 therapeutics.

  11. The roles of outlet density and norms in alcohol use disorder.

    PubMed

    Ahern, Jennifer; Balzer, Laura; Galea, Sandro

    2015-06-01

    Alcohol outlet density and norms shape alcohol consumption. However, due to analytic challenges we do not know: (a) if alcohol outlet density and norms also shape alcohol use disorder, and (b) whether they act in combination to shape disorder. We applied a new targeted minimum loss-based estimator for rare outcomes (rTMLE) to a general population sample from New York City (N = 4000) to examine the separate and combined relations of neighborhood alcohol outlet density and norms around drunkenness with alcohol use disorder. Alcohol use disorder was assessed using the World Mental Health Comprehensive International Diagnostic Interview (WMH-CIDI) alcohol module. Confounders included demographic and socioeconomic characteristics, as well as history of drinking prior to residence in the current neighborhood. Alcohol use disorder prevalence was 1.78%. We found a marginal risk difference for alcohol outlet density of 0.88% (95% CI 0.00-1.77%), and for norms of 2.05% (95% CI 0.89-3.21%), adjusted for confounders. While each exposure had a substantial relation with alcohol use disorder, there was no evidence of additive interaction between the exposures. Results indicate that the neighborhood environment shapes alcohol use disorder. Despite the lack of additive interaction, each exposure had a substantial relation with alcohol use disorder and our findings suggest that alteration of outlet density and norms together would likely be more effective than either one alone. Important next steps include development and testing of multi-component intervention approaches aiming to modify alcohol outlet density and norms toward reducing alcohol use disorder. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  12. [PD-L1 expression and PD-1/PD-L1 inhibitors in breast cancer].

    PubMed

    Monneur, Audrey; Gonçalves, Anthony; Bertucci, François

    2018-03-01

    The development of immune checkpoints inhibitors represents one of the major recent advances in oncology. Monoclonal antibodies directed against the programmed cell death protein 1 (PD-1) or its ligand (PD-L1) provides durable disease control, particularly in melanoma, lung, kidney, bladder and head and neck cancers. The purpose of this review is to synthesize current data on the expression of PD-L1 in breast cancer and on the preliminary clinical results of PD-1/PD-L1 inhibitors in breast cancer patients. In breast cancer, PD-L1 expression is heterogeneous and is generally associated with the presence of tumor-infiltrating lymphocytes as well as the presence of poor-prognosis factors, such as young age, high grade, ER-negativity, PR-negativity, and HER-2 overexpression, high proliferative index, and aggressive molecular subtypes (triple negative, basal-like, HER-2-overexpressing). Its prognostic value remains controversial when assessed with immunohistochemistry, whereas it seems favorable in triple-negative cancers when assessed at the mRNA level. Early clinical trials with PD-1/PD-L1 inhibitors in breast cancer have shown efficacy in terms of tumor response and/or disease control in refractory metastatic breast cancers, notably in the triple-negative subtype. Many trials are currently underway, both in the metastatic and neo-adjuvant setting. A crucial issue is identification of biomarkers predictive of response to PD-1/PD-L1 inhibitors. Copyright © 2018 Société Française du Cancer. Published by Elsevier Masson SAS. All rights reserved.

  13. Sparse Recovery via l1 and L1 Optimization

    DTIC Science & Technology

    2014-11-01

    problem, with t being the descent direc- tion, obtaining ut = uxx + f − 1 µ p(u) (6) as an evolution equation. We can hope that these L1 regularized (or...implementation. He considered a wide class of second–order elliptic equations and, with Friedman [14], an extension to parabolic equa- tions. In [15, 16...obtaining an elliptic PDE, or by gradi- ent descent to obtain a parabolic PDE. Addition- ally, some PDEs can be rewritten using the L1 subgradient such as the

  14. Children's Evaluations of Resource Allocation in the Context of Group Norms

    ERIC Educational Resources Information Center

    Cooley, Shelby; Killen, Melanie

    2015-01-01

    This study investigated children's evaluations of peer group members who deviated from group norms about equal and unequal allocation of resources. Children, ages 3.5 to 4 years and 5 to 6 years (N = 73), were asked to evaluate a peer group member who deviated from 1 of 2 group allocation norms: (a) equal allocation of resources, or (b) unequal…

  15. Reliance on God, Prayer, and Religion Reduces Influence of Perceived Norms on Drinking

    PubMed Central

    Neighbors, Clayton; Brown, Garrett A.; Dibello, Angelo M.; Rodriguez, Lindsey M.; Foster, Dawn W.

    2013-01-01

    Objective: Previous research has shown that perceived social norms are among the strongest predictors of drinking among young adults. Research has also consistently found religiousness to be protective against risk and negative health behaviors. The present research evaluates the extent to which reliance on God, prayer, and religion moderates the association between perceived social norms and drinking. Method: Participants (n = 1,124 undergraduate students) completed a cross-sectional survey online, which included measures of perceived norms, religious values, and drinking. Perceived norms were assessed by asking participants their perceptions of typical student drinking. Drinking outcomes included drinks per week, drinking frequency, and typical quantity consumed. Results: Regression analyses indicated that religiousness and perceived norms had significant unique associations in opposite directions for all three drinking outcomes. Significant interactions were evident between religiousness and perceived norms in predicting drinks per week, frequency, and typical quantity. In each case, the interactions indicated weaker associations between norms and drinking among those who assigned greater importance to religiousness. Conclusions: The extent of the relationship between perceived social norms and drinking was buffered by the degree to which students identified with religiousness. A growing body of literature has shown interventions including personalized feedback regarding social norms to be an effective strategy in reducing drinking among college students. The present research suggests that incorporating religious or spiritual values into student interventions may be a promising direction to pursue. PMID:23490564

  16. Establishing a NORM based radiation calibration facility.

    PubMed

    Wallace, J

    2016-05-01

    An environmental radiation calibration facility has been constructed by the Radiation and Nuclear Sciences unit of Queensland Health at the Forensic and Scientific Services Coopers Plains campus in Brisbane. This facility consists of five low density concrete pads, spiked with a NORM source, to simulate soil and effectively provide a number of semi-infinite uniformly distributed sources for improved energy response calibrations of radiation equipment used in NORM measurements. The pads have been sealed with an environmental epoxy compound to restrict radon loss and so enhance the quality of secular equilibrium achieved. Monte Carlo models (MCNP),used to establish suitable design parameters and identify appropriate geometric correction factors linking the air kerma measured above these calibration pads to that predicted for an infinite plane using adjusted ICRU53 data, are discussed. Use of these correction factors as well as adjustments for cosmic radiation and the impact of surrounding low levels of NORM in the soil, allows for good agreement between the radiation fields predicted and measured above the pads at both 0.15 m and 1 m. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Spanish semantic feature production norms for 400 concrete concepts.

    PubMed

    Vivas, Jorge; Vivas, Leticia; Comesaña, Ana; Coni, Ana García; Vorano, Agostina

    2017-06-01

    Semantic feature production norms provide many quantitative measures of different feature and concept variables that are necessary to solve some debates surrounding the nature of the organization, both normal and pathological, of semantic memory. Despite the current existence of norms for different languages, there are still no published norms in Spanish. This article presents a new set of norms collected from 810 participants for 400 living and nonliving concepts among Spanish speakers. These norms consist of empirical collections of features that participants used to describe the concepts. Four files were elaborated: a concept-feature file, a concept-concept matrix, a feature-feature matrix, and a significantly correlated features file. We expect that these norms will be useful for researchers in the fields of experimental psychology, neuropsychology, and psycholinguistics.

  18. Frontcountry encounter norms among three cultures

    Treesearch

    Jerry J. Vaske; Maureen P. Donnelly; Robert M. Doctor; James P. Petruzzi

    1995-01-01

    Existing normative studies have focused on backcountry encounter norms reported by North Americans. This study extends previous research by comparing encounter norms reported by three different cultures - North Americans, Europeans, and Japanese - in a frontcountry day use recreation area. Data were obtained from on-site surveys distributed at the Columbia Icefield in...

  19. 1-norm and entanglement in screening out braiding from Yang-Baxter equation associated with Z3 parafermion

    NASA Astrophysics Data System (ADS)

    Yu, Li-Wei; Ge, Mo-Lin

    2017-03-01

    The relationships between quantum entangled states and braid matrices have been well studied in recent years. However, most of the results are based on qubits. In this paper, we investigate the applications of 2-qutrit entanglement in the braiding associated with Z3 parafermion. The 2-qutrit entangled state | Ψ (θ) >, generated by the action of the localized unitary solution R ˘ (θ) of YBE on 2-qutrit natural basis, achieves its maximal ℓ1-norm and maximal von Neumann entropy simultaneously at θ = π / 3. Meanwhile, at θ = π / 3, the solutions of YBE reduces braid matrices, which implies the role of ℓ1-norm and entropy plays in determining real physical quantities. On the other hand, we give a new realization of 4-anyon topological basis by qutrit entangled states, then the 9 × 9 localized braid representation in 4-qutrit tensor product space (C3) ⊗ 4 is reduced to Jones representation of braiding in the 4-anyon topological basis. Hence, we conclude that the entangled states are powerful tools in analysing the characteristics of braiding and R ˘ -matrix.

  20. Using Peer Injunctive Norms to Predict Early Adolescent Cigarette Smoking Intentions

    PubMed Central

    Zaleski, Adam C.; Aloise-Young, Patricia A.

    2013-01-01

    The present study investigated the importance of the perceived injunctive norm to predict early adolescent cigarette smoking intentions. A total of 271 6th graders completed a survey that included perceived prevalence of friend smoking (descriptive norm), perceptions of friends’ disapproval of smoking (injunctive norm), and future smoking intentions. Participants also listed their five best friends, in which the actual injunctive norm was calculated. Results showed that smoking intentions were significantly correlated with the perceived injunctive norm but not with the actual injunctive norm. Secondly, the perceived injunctive norm predicted an additional 3.4% of variance in smoking intentions above and beyond the perceived descriptive norm. These results demonstrate the importance of the perceived injunctive norm in predicting early adolescent smoking intentions. PMID:24078745

  1. Trauma in adolescents causes long-term marked deficits in quality of life: adolescent children do not recover preinjury quality of life or function up to two years postinjury compared to national norms.

    PubMed

    Holbrook, Troy Lisa; Hoyt, David B; Coimbra, Raul; Potenza, Bruce; Sise, Michael J; Sack, Dan I; Anderson, John P

    2007-03-01

    Injury is a leading cause of death and preventable morbidity in adolescents. Little is known about long-term quality of life (QoL) outcomes in injured adolescents. The objectives of the present report are to describe long-term QoL outcomes and compare posttrauma QoL to national norms for QoL in uninjured adolescents from the National Health Interview Survey (NHIS). In all, 401 trauma patients aged 12 to 19 years were enrolled in the study. Enrollment criteria excluded spinal cord injury. QoL after trauma was measured using the Quality of Well-being (QWB) scale, a sensitive and well-validated functional index (range: 0 = death to 1.000 = optimum functioning). Patient outcomes were assessed at discharge, and 3, 6, 12, 18, and 24 months after discharge. NHIS data were based on 3 survey years and represent a population-based U.S. national random sample of uninjured adolescents. Major trauma in adolescents was associated with significant and marked deficits in QoL throughout the 24-month follow-up period, compared with NHIS norms for this age group. Compared with NHIS norms for QoL in uninjured adolescents aged 12 to 19 years (N = 81,216,835; QWB mean = 0.876), injured adolescents after major trauma had striking and significant QoL deficits beginning at 3-month follow-up (QWB mean = 0.694, p < 0.0001), that continued throughout the long-term follow-up 24 months after discharge (6-month follow-up QWB mean = 0.726, p < 0.0001; 12-month follow-up QWB mean = 0.747, p < 0.0001; 18-month follow-up QWB mean = 0.758, p < 0.0001; 24-month follow-up QWB mean = 0.766, p < 0.0001). QoL deficits were also strongly associated with age (>or=15 years) and female sex. Other significant risk factors for poor QoL outcomes were perceived threat to life, pedestrian struck mechanism, and Injury Severity Scores >16. Major trauma in adolescents is associated with significant and marked deficits in long-term QoL outcomes, compared with U.S. norms for healthy adolescents. Early identification

  2. Mixed-norm estimates for the M/EEG inverse problem using accelerated gradient methods

    PubMed Central

    Gramfort, Alexandre; Kowalski, Matthieu; Hämäläinen, Matti

    2012-01-01

    Magneto- and electroencephalography (M/EEG) measure the electromagnetic fields produced by the neural electrical currents. Given a conductor model for the head, and the distribution of source currents in the brain, Maxwell’s equations allow one to compute the ensuing M/EEG signals. Given the actual M/EEG measurements and the solution of this forward problem, one can localize, in space and in time, the brain regions than have produced the recorded data. However, due to the physics of the problem, the limited number of sensors compared to the number of possible source locations, and measurement noise, this inverse problem is ill-posed. Consequently, additional constraints are needed. Classical inverse solvers, often called Minimum Norm Estimates (MNE), promote source estimates with a small ℓ2 norm. Here, we consider a more general class of priors based on mixed-norms. Such norms have the ability to structure the prior in order to incorporate some additional assumptions about the sources. We refer to such solvers as Mixed-Norm Estimates (MxNE). In the context of M/EEG, MxNE can promote spatially focal sources with smooth temporal estimates with a two-level ℓ1/ℓ2 mixed-norm, while a three-level mixed-norm can be used to promote spatially non-overlapping sources between different experimental conditions. In order to efficiently solve the optimization problems of MxNE, we introduce fast first-order iterative schemes that for the ℓ1/ℓ2 norm give solutions in a few seconds making such a prior as convenient as the simple MNE. Furhermore, thanks to the convexity of the optimization problem, we can provide optimality conditions that guarantee global convergence. The utility of the methods is demonstrated both with simulations and experimental MEG data. PMID:22421459

  3. Shifting more than the goal posts: developing classroom norms of inquiry-based learning in mathematics

    NASA Astrophysics Data System (ADS)

    Makar, Katie; Fielding-Wells, Jill

    2018-03-01

    The 3-year study described in this paper aims to create new knowledge about inquiry norms in primary mathematics classrooms. Mathematical inquiry addresses complex problems that contain ambiguities, yet classroom environments often do not adopt norms that promote curiosity, risk-taking and negotiation needed to productively engage with complex problems. Little is known about how teachers and students initiate, develop and maintain norms of mathematical inquiry in primary classrooms. The research question guiding this study is, "How do classroom norms develop that facilitate student learning in primary classrooms which practice mathematical inquiry?" The project will (1) analyse a video archive of inquiry lessons to identify signature practices that enhance productive classroom norms of mathematical inquiry and facilitate learning, (2) engage expert inquiry teachers to collaborate to identify and design strategies for assisting teachers to develop and sustain norms over time that are conducive to mathematical inquiry and (3) support and study teachers new to mathematical inquiry adopting these practices in their classrooms. Anticipated outcomes include identification and illustration of classroom norms of mathematical inquiry, signature practices linked to these norms and case studies of primary teachers' progressive development of classroom norms of mathematical inquiry and how they facilitate learning.

  4. Norm compliance and self-reported health among Swedish adolescents.

    PubMed

    Nygren, Karina; Janlert, Urban; Nygren, Lennart

    2011-02-01

    This study examines the relationship between norm compliance and self-reported health in adolescents, and how this differs between genders. Our specific aim was to investigate if extremely high norm compliance revealed any particular health patterns. This empirical study used a web-based survey from 2005, which was distributed to all students (n = 5,066) in years 7-9 of compulsory school within six municipalities in northern Sweden. The respondents answered questions about their general health as well as specific health problems such as headaches, stomach ache, sleeping difficulties and stress. Compliance was measured according to different norm-related behaviour, such as truancy, crime and use of tobacco, alcohol and narcotics. The majority of respondents reported good health and norm-compliant behaviour. Girls reported more health problems than boys, a difference that increased with age. Those who were more norm compliant reported better health, fewer somatic complaints and less stress, which goes against our initial hypothesis that extremely high norm compliance and self-reported ill-health are related. There seemed to be a stronger relationship between self-reported health and norm compliance for girls than boys, in absolute terms. The results clearly show a relationship between norm compliance and health, and suggest inequalities between genders.

  5. Variation in reaction norms: Statistical considerations and biological interpretation.

    PubMed

    Morrissey, Michael B; Liefting, Maartje

    2016-09-01

    Analysis of reaction norms, the functions by which the phenotype produced by a given genotype depends on the environment, is critical to studying many aspects of phenotypic evolution. Different techniques are available for quantifying different aspects of reaction norm variation. We examine what biological inferences can be drawn from some of the more readily applicable analyses for studying reaction norms. We adopt a strongly biologically motivated view, but draw on statistical theory to highlight strengths and drawbacks of different techniques. In particular, consideration of some formal statistical theory leads to revision of some recently, and forcefully, advocated opinions on reaction norm analysis. We clarify what simple analysis of the slope between mean phenotype in two environments can tell us about reaction norms, explore the conditions under which polynomial regression can provide robust inferences about reaction norm shape, and explore how different existing approaches may be used to draw inferences about variation in reaction norm shape. We show how mixed model-based approaches can provide more robust inferences than more commonly used multistep statistical approaches, and derive new metrics of the relative importance of variation in reaction norm intercepts, slopes, and curvatures. © 2016 The Author(s). Evolution © 2016 The Society for the Study of Evolution.

  6. NPC1L1 and Cholesterol Transport

    PubMed Central

    Betters, Jenna L.; Yu, Liqing

    2010-01-01

    The polytopic transmembrane protein, Niemann-Pick C1-Like 1 (NPC1L1), is enriched in the apical membrane of small intestine absorptive enterocytes where it mediates extracellular sterol transport across the brush border membrane. It is essential for intestinal sterol absorption and is the molecular target of ezetimibe, a potent cholesterol absorption inhibitor that lowers blood cholesterol in humans. NPC1L1 is also highly expressed in human liver. The hepatic function of NPC1L1 may be to limit excessive biliary cholesterol loss. NPC1L1-dependent sterol uptake seems to be a clathrin-mediated endocytic process and is regulated by cellular cholesterol content. Recently, NPC1L1 inhibition has been shown to have beneficial effects on components of the metabolic syndrome, such as obesity, insulin resistance, fatty liver, in addition to atherosclerosis. PMID:20307540

  7. A minimal standardization setting for language mapping tests: an Italian example.

    PubMed

    Rofes, Adrià; de Aguiar, Vânia; Miceli, Gabriele

    2015-07-01

    During awake surgery, picture-naming tests are administered to identify brain structures related to language function (language mapping), and to avoid iatrogenic damage. Before and after surgery, naming tests and other neuropsychological procedures aim at charting naming abilities, and at detecting which items the subject can respond to correctly. To achieve this goal, sufficiently large samples of normed and standardized stimuli must be available for preoperative and postoperative testing, and to prepare intraoperative tasks, the latter only including items named flawlessly preoperatively. To discuss design, norming and presentation of stimuli, and to describe the minimal standardization setting used to develop two sets of Italian stimuli, one for object naming and one for verb naming, respectively. The setting includes a naming study (to obtain picture-name agreement ratings), two on-line questionnaires (to acquire age-of-acquisition and imageability ratings for all test items), and the norming of other relevant language variables. The two sets of stimuli have >80 % picture-name agreement, high levels of internal consistency and reliability for imageability and age of acquisition ratings. They are normed for psycholinguistic variables known to affect lexical access and retrieval, and are validated in a clinical population. This framework can be used to increase the probability of reliably detecting language impairments before and after surgery, to prepare intraoperative tests based on sufficient knowledge of pre-surgical language abilities in each patient, and to decrease the probability of false positives during surgery. Examples of data usage are provided. Normative data can be found in the supplementary materials.

  8. Radiation processing of minimally processed vegetables and aromatic plants

    NASA Astrophysics Data System (ADS)

    Trigo, M. J.; Sousa, M. B.; Sapata, M. M.; Ferreira, A.; Curado, T.; Andrada, L.; Botelho, M. L.; Veloso, M. G.

    2009-07-01

    Vegetables are an essential part of people's diet all around the world. Due to cultivate techniques and handling after harvest, these products, may contain high microbial load that can cause food borne outbreaks. The irradiation of minimally processed vegetables is an efficient way to reduce the level of microorganisms and to inhibit parasites, helping a safe global trade. Evaluation of the irradiation's effects was carried out in minimal processed vegetables, as coriander ( Coriandrum sativum L .), mint ( Mentha spicata L.), parsley ( Petroselinum crispum Mill, (A.W. Hill)), lettuce ( Lactuca sativa L.) and watercress ( Nasturium officinale L.). The inactivation level of natural microbiota and the D 10 values of Escherichia coli O157:H7 and Listeria innocua in these products were determined. The physical-chemical and sensorial characteristics before and after irradiation at a range of 0.5 up to 2.0 kGy applied doses were also evaluated. No differences were verified in the overall of sensorial and physical properties after irradiation up to 1 kGy, a decrease of natural microbiota was noticed (⩾2 log). Based on the determined D10, the amount of radiation necessary to kill 10 5E. coli and L. innocua was between 0.70 and 1.55 kGy. Shelf life of irradiated coriander, mint and lettuce at 0.5 kGy increased 2, 3 and 4 days, respectively, when compared with non-irradiated.

  9. Integrating Meaning and Structure in L1-L2 and L2-L1 Translations

    ERIC Educational Resources Information Center

    Lim, Jung Hyun; Christianson, Kiel

    2013-01-01

    This article examined the integration of semantic and morphosyntactic information by Korean learners of English as a second language (L2). In Experiment 1, L2 learners listened to English active or passive sentences that were either plausible or implausible and translated them into Korean. A significant number of Korean translations maintained the…

  10. L1 and L2 Distance Effects in Learning L3 Dutch

    ERIC Educational Resources Information Center

    Schepens, Job J.; der Slik, Frans; Hout, Roeland

    2016-01-01

    Many people speak more than two languages. How do languages acquired earlier affect the learnability of additional languages? We show that linguistic distances between speakers' first (L1) and second (L2) languages and their third (L3) language play a role. Larger distances from the L1 to the L3 and from the L2 to the L3 correlate with lower…

  11. Eating for Two? Protocol of an Exploratory Survey and Experimental Study on Social Norms and Norm-Based Messages Influencing European Pregnant and Non-pregnant Women's Eating Behavior.

    PubMed

    Bevelander, Kirsten E; Herte, Katharina; Kakoulakis, Catherine; Sanguino, Inés; Tebbe, Anna-Lena; Tünte, Markus R

    2018-01-01

    The social context is an important factor underlying unhealthy eating behavior and the development of inappropriate weight gain. Evidence is accumulating that powerful social influences can also be used as a tool to impact people's eating behavior in a positive manner. Social norm-based messages have potential to steer people in making healthier food choices. The research field on nutritional social norms is still emerging and more research is needed to gain insights into why some people adhere to social norms whereas others do not. There are indications stemming from empirical studies on social eating behavior that this may be due to ingratiation purposes and uncertainty reduction. That is, people match their eating behavior to that of the norm set by their eating companion(s) in order to blend in and be part of the group. In this project, we explore nutritional social norms among pregnant women. This population is particularly interesting because they are often subject to unsolicited advice and experience social pressure from their environment. In addition, their pregnancy affects their body composition, eating pattern, and psychosocial status. Pregnancy provides an important window of opportunity to impact health of pregnant women and their child. Nevertheless, the field of nutritional social norms among pregnant women is understudied and more knowledge is needed on whether pregnant women use guidelines from their social environment for their own eating behavior. In this project we aim to fill this research gap by means of an exploratory survey (Study 1) assessing information about social expectations, (mis)perceived social norms and the role of different reference groups such as other pregnant women, family, and friends. In addition, we conduct an online experiment (Study 2) testing to what extent pregnant women are susceptible to social norm-based messages compared to non-pregnant women. Moreover, possible moderators are explored which might impact women

  12. Fast Algorithms for Earth Mover Distance Based on Optimal Transport and L1 Regularization II

    DTIC Science & Technology

    2016-09-01

    of optimal transport, the EMD problem can be reformulated as a familiar L1 minimization. We use a regularization which gives us a unique solution for...plays a central role in many applications, including image processing, computer vision and statistics etc. [13, 17, 20, 24]. The EMD is a metric defined

  13. Processing of English Focal Stress by L1-English and L1-Mandarin/L2-English Speakers

    ERIC Educational Resources Information Center

    Guigelaar, Ellen R.

    2017-01-01

    Late second language (L2) learners often struggle with L2 prosody, both in perception and production. This may result from first language (L1) interference or some property of how a second language functions in a late learner independent of what their L1 might be. Here we investigate prosody's role in determining information structure through…

  14. Parent and Grandparent Marijuana Use and Child Substance Use and Norms

    PubMed Central

    Bailey, Jennifer A.; Hill, Karl G.; Guttmannova, Katarina; Epstein, Marina; Abbott, Robert D.; Steeger, Christine M.; Skinner, Martie L.

    2016-01-01

    Purpose Using prospective longitudinal data from 3 generations, this study seeks to test whether and how parent and grandparent marijuana use (current and prior) predicts an increased likelihood of child cigarette, alcohol, and marijuana use. Methods Using multilevel modeling of prospective data spanning 3 generations (N = 306 families, children ages 6-22), this study tested associations between grandparent (G1) and parent (G2) marijuana use and child (G3) past-year cigarette, alcohol, and marijuana use. Analyses tested whether G3 substance-related norms mediated these associations. Current G1 and G2 marijuana use was examined, as was G2 high school and early adult use and G1 marijuana use when G2 parents were in early adolescence. Controls included G2 age at G3 birth, G2 education and depression, and G3 gender. Results G2 current marijuana use predicted a higher likelihood of G3 alcohol and marijuana use, but was not related to the probability of G3 cigarette use. G3's perceptions of their parents' norms and G2 current marijuana use both contributed independently to the likelihood of G3 alcohol and marijuana use when included in the same model. G3 children's own norms and their perceptions of friends' norms mediated the link between G2 current marijuana use and G3 alcohol and marijuana use. Conclusions Results are discussed in light of the growing trend toward marijuana legalization. To the extent that parent marijuana use increases under legalization, we can expect more youth to use alcohol and marijuana and to have norms that favor substance use. PMID:27265424

  15. NORM -- The new kid on the block

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Estey, H.P.

    1991-12-31

    The existence of radioactive materials in accumulations of scale and sludge in oil and gas production equipment is a relatively new issue. This developing issue first gained international attention in 1981 when significant radiation levels were detected on oil and gas production platforms in the North Sea; it didn`t become a domestic issue until 1986 when a similar situation was detected in a Mississippi pipe yard. Most published papers on the occurrence of Naturally Occurring Radioactive Materials (NORM) in oil and gas production equipment have been based on studies of NORM-related activities in the United Kingdom (North Sea NORM). Thismore » paper addresses the occurrences and regulation of NORM in the US oil and gas production industry as experienced, witnessed and/or observed by the author over the past four years.« less

  16. "Be Nice": Wikipedia norms for supportive communication

    NASA Astrophysics Data System (ADS)

    Reagle, Joseph M.

    2010-04-01

    Wikipedia is acknowledged to have been home to "some bitter disputes." Indeed, conflict at Wikipedia is said to be "as addictive as cocaine." Yet, such observations are not cynical commentary but motivation for a collection of social norms. These norms speak to the intentional stance and communicative behaviors Wikipedians should adopt when interacting with one another. In the following pages, I provide a survey of these norms on the English Wikipedia and argue that they can be characterized as supportive based on Jack Gibb's classic communication article "Defensive Communication."

  17. PD-1/PD-L1 in disease.

    PubMed

    Kuol, Nyanbol; Stojanovska, Lily; Nurgali, Kulmira; Apostolopoulos, Vasso

    2018-02-01

    Expression of PD-1 on T/B cells regulates peripheral tolerance and autoimmunity. Binding of PD-1 to its ligand, PD-L1, leads to protection against self-reactivity. In contrary, tumor cells have evolved immune escape mechanisms whereby overexpression of PD-L1 induces anergy and/or apoptosis of PD-1 positive T cells by interfering with T cell receptor signal transduction. PD-L1 and PD-1 blockade using antibodies are in human clinical trials as an alternative cancer treatment modality. Areas covered: We describe the role of PD-1/PD-L1 in disease in the context of autoimmunity, neurological disorders, stroke and cancer. For immunotherapy/vaccines to be successful, the expression of PD-L1/PD-1 on immune cells should be considered, and the combination of checkpoint inhibitors and vaccines may pave the way for successful outcomes to disease.

  18. How preschoolers react to norm violations is associated with culture.

    PubMed

    Gampe, Anja; Daum, Moritz M

    2018-01-01

    Children from the age of 3years understand social norms as such and enforce these norms in interactions with others. Differences in parental and institutional education across cultures make it likely that children receive divergent information about how to act in cases of norm violations. In the current study, we investigated whether cultural values are associated with the ways in which children react to norm violations. We tested 80 bicultural 3-year-olds with a norm enforcement paradigm and analyzed their reactions to norm violations. The reactions were correlated to the children's parental cultural values using the Global Leadership and Organizational Behavior Effectiveness (GLOBE) scales, and these results show that parental culture was associated with children's reactions to norm violations. The three strongest correlations were found for institutional collectivism, performance orientation, and assertiveness. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Alcohol Expectancies, Perceived Norms and Drinking Behavior among College Students: Examining the Reciprocal Determinism Hypothesis

    PubMed Central

    Wardell, Jeffrey D.; Read, Jennifer P.

    2012-01-01

    Social learning mechanisms, such as descriptive norms for drinking behavior (norms) and positive alcohol expectancies (PAEs), play a major role in college student alcohol use. According to the principle of reciprocal determinism (Bandura, 1977), norms and PAEs should be reciprocally associated with alcohol use, each influencing one another over time. However, the nature of these prospective relationships for college students is in need of further investigation. This study provided the first examination of the unique reciprocal associations among norms, PAEs, and drinking together in a single model. PAEs become more stable with age, whereas norms are likely to be more dynamic upon college entry. Thus, we hypothesized that alcohol use would show stronger reciprocal associations with norms than with PAEs for college students. Students (N=557; 67% female) completed online measures of PAEs, norms and quantity and frequency of alcohol use in September of their first (T1), second (T2), and third (T3) years of college. Reciprocal associations were analyzed using a cross-lagged panel design. PAEs had unidirectional influences on frequency and quantity of alcohol use, with no prospective effects from alcohol use to PAEs. Reciprocal associations were observed between norms and alcohol use, but only for quantity and not frequency. Specifically, drinking quantity prospectively predicted quantity norms and quantity norms prospectively predicted drinking quantity. This effect was observed across both years in the model. These findings support the reciprocal determinism hypothesis for norms but not for PAEs in college students, and may help to inform norm-based interventions. PMID:23088403

  20. Alcohol expectancies, perceived norms, and drinking behavior among college students: examining the reciprocal determinism hypothesis.

    PubMed

    Wardell, Jeffrey D; Read, Jennifer P

    2013-03-01

    Social learning mechanisms, such as descriptive norms for drinking behavior (norms) and positive alcohol expectancies (PAEs), play a major role in college student alcohol use. According to the principle of reciprocal determinism (Bandura, 1977), norms and PAEs should be reciprocally associated with alcohol use, each influencing one another over time. However, the nature of these prospective relationships for college students is in need of further investigation. This study provided the first examination of the unique reciprocal associations among norms, PAEs, and drinking together in a single model. PAEs become more stable with age, whereas norms are likely to be more dynamic upon college entry. Thus, we hypothesized that alcohol use would show stronger reciprocal associations with norms than with PAEs for college students. Students (N = 557; 67% women) completed online measures of PAEs, norms, and quantity and frequency of alcohol use in September of their first (T1), second (T2), and third (T3) years of college. Reciprocal associations were analyzed using a cross-lagged panel design. PAEs had unidirectional influences on frequency and quantity of alcohol use, with no prospective effects from alcohol use to PAEs. Reciprocal associations were observed between norms and alcohol use, but only for quantity and not for frequency. Specifically, drinking quantity prospectively predicted quantity norms and quantity norms prospectively predicted drinking quantity. This effect was observed across both years in the model. These findings support the reciprocal determinism hypothesis for norms but not for PAEs in college students and may help to inform norm-based interventions. (PsycINFO Database Record (c) 2013 APA, all rights reserved).

  1. A graph-based approach to auditing RxNorm.

    PubMed

    Bodenreider, Olivier; Peters, Lee B

    2009-06-01

    RxNorm is a standardized nomenclature for clinical drug entities developed by the National Library of Medicine. In this paper, we audit relations in RxNorm for consistency and completeness through the systematic analysis of the graph of its concepts and relationships. The representation of multi-ingredient drugs is normalized in order to make it compatible with that of single-ingredient drugs. All meaningful paths between two nodes in the type graph are computed and instantiated. Alternate paths are automatically compared and manually inspected in case of inconsistency. The 115 meaningful paths identified in the type graph can be grouped into 28 groups with respect to start and end nodes. Of the 19 groups of alternate paths (i.e., with two or more paths) between the start and end nodes, 9 (47%) exhibit inconsistencies. Overall, 28 (24%) of the 115 paths are inconsistent with other alternate paths. A total of 348 inconsistencies were identified in the April 2008 version of RxNorm and reported to the RxNorm team, of which 215 (62%) had been corrected in the January 2009 version of RxNorm. The inconsistencies identified involve missing nodes (93), missing links (17), extraneous links (237) and one case of mix-up between two ingredients. Our auditing method proved effective in identifying a limited number of errors that had defeated the quality assurance mechanisms currently in place in the RxNorm production system. Some recommendations for the development of RxNorm are provided.

  2. Determining the Minimal Required Radioactivity of 18F-FDG for Reliable Semiquantification in PET/CT Imaging: A Phantom Study.

    PubMed

    Chen, Ming-Kai; Menard, David H; Cheng, David W

    2016-03-01

    In pursuit of as-low-as-reasonably-achievable (ALARA) doses, this study investigated the minimal required radioactivity and corresponding imaging time for reliable semiquantification in PET/CT imaging. Using a phantom containing spheres of various diameters (3.4, 2.1, 1.5, 1.2, and 1.0 cm) filled with a fixed (18)F-FDG concentration of 165 kBq/mL and a background concentration of 23.3 kBq/mL, we performed PET/CT at multiple time points over 20 h of radioactive decay. The images were acquired for 10 min at a single bed position for each of 10 half-lives of decay using 3-dimensional list mode and were reconstructed into 1-, 2-, 3-, 4-, 5-, and 10-min acquisitions per bed position using an ordered-subsets expectation maximum algorithm with 24 subsets and 2 iterations and a gaussian 2-mm filter. SUVmax and SUVavg were measured for each sphere. The minimal required activity (±10%) for precise SUVmax semiquantification in the spheres was 1.8 kBq/mL for an acquisition of 10 min, 3.7 kBq/mL for 3-5 min, 7.9 kBq/mL for 2 min, and 17.4 kBq/mL for 1 min. The minimal required activity concentration-acquisition time product per bed position was 10-15 kBq/mL⋅min for reproducible SUV measurements within the spheres without overestimation. Using the total radioactivity and counting rate from the entire phantom, we found that the minimal required total activity-time product was 17 MBq⋅min and the minimal required counting rate-time product was 100 kcps⋅min. Our phantom study determined a threshold for minimal radioactivity and acquisition time for precise semiquantification in (18)F-FDG PET imaging that can serve as a guide in pursuit of achieving ALARA doses. © 2016 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

  3. Social Norms, Acculturation, and Physical Activity Among Latina Women.

    PubMed

    Abraído-Lanza, Ana F; Shelton, Rachel C; Martins, Mariana Cunha; Crookes, Danielle M

    2017-04-01

    Physical activity promotes health and is important for preventing chronic conditions, such as obesity and cardiovascular disease. Little is known about factors associated with different types of PA among Latina women, particularly Dominicans, who now constitute the fifth largest group of Latinos in the United States. The purpose of this study was to examine whether occupational physical activity, acculturation, familism, and norms held by family and friends are associated with three types of PA: vigorous and moderate leisure-time physical activity (LTPA), and resistance training. Interviews were conducted with 418 Dominican women. We assessed self-reported PA using standardized measures. Data were collected between July 2010 and July 2012 in New York City. Most women reported no vigorous LTPA or resistance training (74.5 and 73.1 %, respectively); about half (52.1 %) reported no moderate LTPA. After adjusting for sociodemographic factors, occupational physical activities were associated with greater LTPA. Acculturation was not associated with any outcome. Positive family norms about exercise were associated with increased LTPA and resistance training. Family norms may play a critical role in PA and should be included in programs to increase PA among Latina women.

  4. Regulating Gender Performances: Power and Gender Norms in Faculty Work

    ERIC Educational Resources Information Center

    Lester, Jaime

    2011-01-01

    Despite the steady increase of women in faculty positions over the last few decades and the research on gender norms in the academy, what remains unclear is why many female faculty continue to conform to gender norms despite their acknowledgement of the discriminatory nature of these norms, their dissatisfaction performing the norms, and the lack…

  5. Social Norms Shift Preferences for Healthy and Unhealthy Foods

    PubMed Central

    Templeton, Emma M.; Stanton, Michael V.; Zaki, Jamil

    2016-01-01

    This research investigated whether people change their food preferences and eating behavior in response to health-based social norms. One hundred twenty participants rated a series of healthy and unhealthy food images. After each rating, participants sometimes viewed a rating that ostensibly represented the average rating of previous participants. In fact, these average ratings were manipulated to convey a particular social norm. Participants either saw average ratings that favored healthy foods, favored unhealthy foods, or did not see any average ratings. Participants then re-rated those same food images after approximately ten minutes and again three days later. After the norm manipulation, participants were given the chance to take as many M&Ms as they wanted. Participants exposed to a healthy social norm consistently reported lower preferences for unhealthy foods as compared to participants in the other two conditions. This preference difference persisted three days after the social norm manipulation. However, health-based social norm manipulations did not influence the amount of M&Ms participants took. Although health-based social norm manipulations can influence stated food preferences, in this case they did not influence subsequent eating behavior. PMID:27861518

  6. The moderating role of peer norms in the associations of social withdrawal and aggression with peer victimization.

    PubMed

    Guimond, Fanny-Alexandra; Brendgen, Mara; Correia, Stephanie; Turgeon, Lyse; Vitaro, Frank

    2018-06-21

    This study examined the moderating role of classroom injunctive norms salience regarding social withdrawal and regarding aggression in the longitudinal association between these behaviors and peer victimization. A total of 1,769 fourth through sixth graders (895 girls, M = 10.25 years, SD = 1.03) from 23 schools (67 classrooms) completed a peer nomination inventory in the fall (T1) and spring (T2) of the same academic year. Participants circled the name of each student who fit the description provided for social withdrawal, aggression, and peer victimization at T1 and T2. The salience of injunctive norms was sex-specific and operationalized by the extent to which children displaying the behavior were socially rewarded or sanctioned by their classmates. Generalized estimation equations (GEE) showed that the association between social withdrawal at T1 and peer victimization at T2 was moderated by injunctive norms. Social withdrawal at T1 was positively associated with peer victimization at T2 in classrooms where injunctive norms for this behavior were salient and unfavorable, as well as in classrooms where injunctive norms for aggression were salient and favorable, albeit for girls only. The association between aggression at T1 and peer victimization at T2 was also moderated by the injunctive norms regarding this behavior. Aggressive children were less likely to be victimized in classrooms where this behavior was rewarded. These results support bullying interventions that target factors related to the larger peer context, including social norms. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  7. Minimal Left-Right Symmetric Dark Matter.

    PubMed

    Heeck, Julian; Patra, Sudhanwa

    2015-09-18

    We show that left-right symmetric models can easily accommodate stable TeV-scale dark matter particles without the need for an ad hoc stabilizing symmetry. The stability of a newly introduced multiplet either arises accidentally as in the minimal dark matter framework or comes courtesy of the remaining unbroken Z_{2} subgroup of B-L. Only one new parameter is introduced: the mass of the new multiplet. As minimal examples, we study left-right fermion triplets and quintuplets and show that they can form viable two-component dark matter. This approach is, in particular, valid for SU(2)×SU(2)×U(1) models that explain the recent diboson excess at ATLAS in terms of a new charged gauge boson of mass 2 TeV.

  8. Potential Applications of Social Norms Theory to Academic Advising

    ERIC Educational Resources Information Center

    Demetriou, Cynthia

    2005-01-01

    Since the mid-1990s, social norms theory has become prevalent in student development literature and research. Subsequently, social norms interventions to change student behavior have spread across campuses nationwide through marketing campaigns. Theorists and practitioners have applied the social norms approach to primarily health-related student…

  9. Cultural variation in communal versus exchange norms: Implications for social support.

    PubMed

    Miller, Joan G; Akiyama, Hiroko; Kapadia, Shagufa

    2017-07-01

    Whereas an interdependent cultural view of self has been linked to communal norms and to socially supportive behavior, its relationship to social support has been called into question in research suggesting that discomfort in social support is associated with an interdependent cultural view of self (e.g., Taylor et al., 2004). These contrasting claims were addressed in 2 studies conducted among Japanese, Indian, and American adults. Assessing everyday social support, Study 1 showed that Japanese and Americans rely on exchange norms more frequently than Indians among friends, whereas American rely on exchange norms more frequently than Indians and Japanese among siblings. Assessing responses to vignettes, Study 2 demonstrated that Japanese and Americans rely more frequently on exchange norms than Indians, with greatest relational concerns and most negative outlooks on social support observed among Japanese, less among Americans, and least among Indians. Results further indicated that relational concerns mediated the link between exchange norms and negative social support outlooks. Supporting past claims that relational concerns explain cultural variation in discomfort in social support (e.g., Kim, Sherman, & Taylor, 2008), the findings underscore the need to take into account as well the role of exchange norms in explaining such discomfort. The findings also highlight the existence of culturally variable approaches to exchange and call into question claims that discomfort in social support can be explained in terms of the global concept of an interdependent cultural view of self. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  10. Taxonomic structure of the yeasts and lactic acid bacteria microbiota of pineapple (Ananas comosus L. Merr.) and use of autochthonous starters for minimally processing.

    PubMed

    Di Cagno, Raffaella; Cardinali, Gainluigi; Minervini, Giovanna; Antonielli, Livio; Rizzello, Carlo Giuseppe; Ricciuti, Patrizia; Gobbetti, Marco

    2010-05-01

    Pichia guilliermondii was the only identified yeast in pineapple fruits. Lactobacillus plantarum and Lactobacillus rossiae were the main identified species of lactic acid bacteria. Typing of lactic acid bacteria differentiated isolates depending on the layers. L. plantarum 1OR12 and L. rossiae 2MR10 were selected within the lactic acid bacteria isolates based on the kinetics of growth and acidification. Five technological options, including minimal processing, were considered for pineapple: heating at 72 degrees C for 15 s (HP); spontaneous fermentation without (FP) or followed by heating (FHP), and fermentation by selected autochthonous L. plantarum 1OR12 and L. rossiae 2MR10 without (SP) or preceded by heating (HSP). After 30 days of storage at 4 degrees C, HSP and SP had a number of lactic acid bacteria 1000 to 1,000,000 times higher than the other processed pineapples. The number of yeasts was the lowest in HSP and SP. The Community Level Catabolic Profiles of processed pineapples indirectly confirmed the capacity of autochthonous starters to dominate during fermentation. HSP and SP also showed the highest antioxidant activity and firmness, the better preservation of the natural colours and were preferred for odour and overall acceptability. Copyright (c) 2009 Elsevier Ltd. All rights reserved.

  11. [Psychological Distress and Acceptance of Violence Legitimizing Masculinity Norms among Adolescents].

    PubMed

    Klein, Eva M; Wölfling, Klaus; Beutel, Manfred E; Dreier, Michael; Müller, Kai W

    2017-04-01

    The proportion of adolescent migrants in Germany aged 15-20 years has risen to about 29.5% in 2014 according to Federal census statistics. The purpose of the current study was to describe and to compare the psychological strains of adolescent 1 st and 2 nd generation migrants with non-migrants in a representative school survey. Acceptance of violence legitimizing masculinity norms was explored and its correlation with psychological strain was analyzed. Self-reported data of psychological strain (internalizing and externalizing problems) and acceptance of violence legitimizing masculinity were gathered among 8 518 pupils aged 12-19 years across different school types. Among the surveyed adolescents, 27.6% reported a migration background (5.8% 1 st generation migrants; 21.8% 2 nd generation migrants). Particularly 1 st generation migrants scored higher in internalizing and externalizing problems than 2 nd generation migrants or non-migrants. The differences, however, were small. Adolescents with migration background suffered from educational disadvantage, especially 1 st generation migrants. Male adolescents reported significantly higher acceptance of violence legitimizing masculinity norms than their female counterparts. Strong agreement with the measured concept of masculinity was found among pupils of lower secondary school and adolescents reported regularly tobacco and cannabis consumption. The acceptance of violence legitimizing masculinity norms was greater among migrants, particularly 1 st generation migrants, than non-migrants. Overall, high acceptance of violence legitimizing masculinity norms was related to externalizing problems, which can be understood as dysfunctional coping mechanisms of social disadvantage and a lack of prospects. © Georg Thieme Verlag KG Stuttgart · New York.

  12. Group bias in cooperative norm enforcement

    PubMed Central

    McAuliffe, Katherine; Dunham, Yarrow

    2016-01-01

    A hallmark of human social cognition is the tendency for both adults and children to favour members of their own groups. Critically, this in-group bias exerts a strong influence on cooperative decision-making: people (i) tend to share more with members of their in-group and (ii) differentially enforce fairness norms depending on the group membership of their interaction partners. But why do people show these group biases in cooperation? One possibility is that the enforcement of cooperative norm violations is an evolved mechanism supporting within-group cooperation (Norms-Focused Hypothesis). Alternatively, group bias in cooperation could be a by-product of more general affective preferences for in-group members (Mere Preferences Hypothesis). Here, we appraise evidence from studies of both adults and children with the goal of understanding whether one of these two accounts is better supported by existing data. While the pattern of evidence is complex, much of it is broadly consistent with the Mere Preferences Hypothesis and little is uniquely supportive of the Norms-Focused Hypothesis. We highlight possible reasons for this complexity and suggest ways that future work can continue to help us understand the important relationship between group bias and cooperation. PMID:26644592

  13. Standardization and performance evaluation of "modified" and "ultrasensitive" versions of the Abbott RealTime HIV-1 assay, adapted to quantify minimal residual viremia.

    PubMed

    Amendola, Alessandra; Bloisi, Maria; Marsella, Patrizia; Sabatini, Rosella; Bibbò, Angela; Angeletti, Claudio; Capobianchi, Maria Rosaria

    2011-09-01

    Numerous studies investigating clinical significance of HIV-1 minimal residual viremia (MRV) suggest potential utility of assays more sensitive than those routinely used to monitor viral suppression. However currently available methods, based on different technologies, show great variation in detection limit and input plasma volume, and generally suffer from lack of standardization. In order to establish new tools suitable for routine quantification of minimal residual viremia in patients under virological suppression, some modifications were introduced into standard procedure of the Abbott RealTime HIV-1 assay leading to a "modified" and an "ultrasensitive" protocols. The following modifications were introduced: calibration curve extended towards low HIV-1 RNA concentration; 4 fold increased sample volume by concentrating starting material; reduced volume of internal control; adoption of "open-mode" software for quantification. Analytical performances were evaluated using the HIV-1 RNA Working Reagent 1 for NAT assays (NIBSC). Both tests were applied to clinical samples from virologically suppressed patients. The "modified" and the "ultrasensitive" configurations of the assay reached a limit of detection of 18.8 (95% CI: 11.1-51.0 cp/mL) and 4.8 cp/mL (95% CI: 2.6-9.1 cp/mL), respectively, with high precision and accuracy. In clinical samples from virologically suppressed patients, "modified" and "ultrasensitive" protocols allowed to detect and quantify HIV RNA in 12.7% and 46.6%, respectively, of samples resulted "not-detectable", and in 70.0% and 69.5%, respectively, of samples "detected <40 cp/mL" in the standard assay. The "modified" and "ultrasensitive" assays are precise and accurate, and easily adoptable in routine diagnostic laboratories for measuring MRV. Copyright © 2011 Elsevier B.V. All rights reserved.

  14. Eating for Two? Protocol of an Exploratory Survey and Experimental Study on Social Norms and Norm-Based Messages Influencing European Pregnant and Non-pregnant Women’s Eating Behavior

    PubMed Central

    Bevelander, Kirsten E.; Herte, Katharina; Kakoulakis, Catherine; Sanguino, Inés; Tebbe, Anna-Lena; Tünte, Markus R.

    2018-01-01

    The social context is an important factor underlying unhealthy eating behavior and the development of inappropriate weight gain. Evidence is accumulating that powerful social influences can also be used as a tool to impact people’s eating behavior in a positive manner. Social norm-based messages have potential to steer people in making healthier food choices. The research field on nutritional social norms is still emerging and more research is needed to gain insights into why some people adhere to social norms whereas others do not. There are indications stemming from empirical studies on social eating behavior that this may be due to ingratiation purposes and uncertainty reduction. That is, people match their eating behavior to that of the norm set by their eating companion(s) in order to blend in and be part of the group. In this project, we explore nutritional social norms among pregnant women. This population is particularly interesting because they are often subject to unsolicited advice and experience social pressure from their environment. In addition, their pregnancy affects their body composition, eating pattern, and psychosocial status. Pregnancy provides an important window of opportunity to impact health of pregnant women and their child. Nevertheless, the field of nutritional social norms among pregnant women is understudied and more knowledge is needed on whether pregnant women use guidelines from their social environment for their own eating behavior. In this project we aim to fill this research gap by means of an exploratory survey (Study 1) assessing information about social expectations, (mis)perceived social norms and the role of different reference groups such as other pregnant women, family, and friends. In addition, we conduct an online experiment (Study 2) testing to what extent pregnant women are susceptible to social norm-based messages compared to non-pregnant women. Moreover, possible moderators are explored which might impact women

  15. Peer punishment promotes enforcement of bad social norms.

    PubMed

    Abbink, Klaus; Gangadharan, Lata; Handfield, Toby; Thrasher, John

    2017-09-20

    Social norms are an important element in explaining how humans achieve very high levels of cooperative activity. It is widely observed that, when norms can be enforced by peer punishment, groups are able to resolve social dilemmas in prosocial, cooperative ways. Here we show that punishment can also encourage participation in destructive behaviours that are harmful to group welfare, and that this phenomenon is mediated by a social norm. In a variation of a public goods game, in which the return to investment is negative for both group and individual, we find that the opportunity to punish led to higher levels of contribution, thereby harming collective payoffs. A second experiment confirmed that, independently of whether punishment is available, a majority of subjects regard the efficient behaviour of non-contribution as socially inappropriate. The results show that simply providing a punishment opportunity does not guarantee that punishment will be used for socially beneficial ends, because the social norms that influence punishment behaviour may themselves be destructive.Punishment by peers can enforce social norms, such as contributing to a public good. Here, Abbink and colleagues show that individuals will enforce norms even when contributions reduce the net benefit of the group, resulting in the maintenance of wasteful contributions.

  16. Full waveform inversion using envelope-based global correlation norm

    NASA Astrophysics Data System (ADS)

    Oh, Ju-Won; Alkhalifah, Tariq

    2018-05-01

    To increase the feasibility of full waveform inversion on real data, we suggest a new objective function, which is defined as the global correlation of the envelopes of modelled and observed data. The envelope-based global correlation norm has the advantage of the envelope inversion that generates artificial low-frequency information, which provides the possibility to recover long-wavelength structure in an early stage. In addition, the envelope-based global correlation norm maintains the advantage of the global correlation norm, which reduces the sensitivity of the misfit to amplitude errors so that the performance of inversion on real data can be enhanced when the exact source wavelet is not available and more complex physics are ignored. Through the synthetic example for 2-D SEG/EAGE overthrust model with inaccurate source wavelet, we compare the performance of four different approaches, which are the least-squares waveform inversion, least-squares envelope inversion, global correlation norm and envelope-based global correlation norm. Finally, we apply the envelope-based global correlation norm on the 3-D Ocean Bottom Cable (OBC) data from the North Sea. The envelope-based global correlation norm captures the strong reflections from the high-velocity caprock and generates artificial low-frequency reflection energy that helps us recover long-wavelength structure of the model domain in the early stages. From this long-wavelength model, the conventional global correlation norm is sequentially applied to invert for higher-resolution features of the model.

  17. Minimal entropy probability paths between genome families.

    PubMed

    Ahlbrandt, Calvin; Benson, Gary; Casey, William

    2004-05-01

    We develop a metric for probability distributions with applications to biological sequence analysis. Our distance metric is obtained by minimizing a functional defined on the class of paths over probability measures on N categories. The underlying mathematical theory is connected to a constrained problem in the calculus of variations. The solution presented is a numerical solution, which approximates the true solution in a set of cases called rich paths where none of the components of the path is zero. The functional to be minimized is motivated by entropy considerations, reflecting the idea that nature might efficiently carry out mutations of genome sequences in such a way that the increase in entropy involved in transformation is as small as possible. We characterize sequences by frequency profiles or probability vectors, in the case of DNA where N is 4 and the components of the probability vector are the frequency of occurrence of each of the bases A, C, G and T. Given two probability vectors a and b, we define a distance function based as the infimum of path integrals of the entropy function H( p) over all admissible paths p(t), 0 < or = t< or =1, with p(t) a probability vector such that p(0)=a and p(1)=b. If the probability paths p(t) are parameterized as y(s) in terms of arc length s and the optimal path is smooth with arc length L, then smooth and "rich" optimal probability paths may be numerically estimated by a hybrid method of iterating Newton's method on solutions of a two point boundary value problem, with unknown distance L between the abscissas, for the Euler-Lagrange equations resulting from a multiplier rule for the constrained optimization problem together with linear regression to improve the arc length estimate L. Matlab code for these numerical methods is provided which works only for "rich" optimal probability vectors. These methods motivate a definition of an elementary distance function which is easier and faster to calculate, works on non

  18. A Graph-based Approach to Auditing RxNorm

    PubMed Central

    Bodenreider, Olivier; Peters, Lee B.

    2009-01-01

    Objectives RxNorm is a standardized nomenclature for clinical drug entities developed by the National Library of Medicine. In this paper, we audit relations in RxNorm for consistency and completeness through the systematic analysis of the graph of its concepts and relationships. Methods The representation of multi-ingredient drugs is normalized in order to make it compatible with that of single-ingredient drugs. All meaningful paths between two nodes in the type graph are computed and instantiated. Alternate paths are automatically compared and manually inspected in case of inconsistency. Results The 115 meaningful paths identified in the type graph can be grouped into 28 groups with respect to start and end nodes. Of the 19 groups of alternate paths (i.e., with two or more paths) between the start and end nodes, 9 (47%) exhibit inconsistencies. Overall, 28 (24%) of the 115 paths are inconsistent with other alternate paths. A total of 348 inconsistencies were identified in the April 2008 version of RxNorm and reported to the RxNorm team, of which 215 (62%) had been corrected in the January 2009 version of RxNorm. Conclusion The inconsistencies identified involve missing nodes (93), missing links (17), extraneous links (237) and one case of mix-up between two ingredients. Our auditing method proved effective in identifying a limited number of errors that had defeated the quality assurance mechanisms currently in place in the RxNorm production system. Some recommendations for the development of RxNorm are provided. PMID:19394440

  19. Changing Gender Norms and Marriage Dynamics in the United States.

    PubMed

    Pessin, Léa

    2018-02-01

    Using a regional measure of gender norms from the General Social Surveys together with marital histories from the Panel Study of Income Dynamics, this study explored how gender norms were associated with women's marriage dynamics between 1968 and 2012. Results suggested that a higher prevalence of egalitarian gender norms predicted a decline in marriage formation. This decline was, however, only true for women without a college degree. For college-educated women, the association between gender norms and marriage formation became positive when gender egalitarianism prevailed. The findings also revealed an inverted U-shaped relationship between gender norms and divorce: an initial increase in divorce was observed when gender norms were predominantly traditional. The association, however, reversed as gender norms became egalitarian. No differences by education were found for divorce. The findings partially support the gender revolution framework but also highlight greater barriers to marriage for low-educated women as societies embrace gender equality.

  20. Vitamin D supplementation in young children: associations with Theory of Planned Behaviour variables, descriptive norms, moral norms and habits.

    PubMed

    de Nooijer, Jascha; Onnink, Monique; van Assema, Patricia

    2010-08-01

    In the Netherlands, a supplementation of 10 microg vitamin D is recommended for children (aged 0-4 years), given that vitamin D contributes to the development of healthy bones and deficiency during childhood is a risk factor for osteoporosis at a later age. However, only 60 % of the Dutch children receive sufficient vitamin D supplementation a day. In order to develop interventions to improve supplementation intake, it is necessary to gain insight into the behaviour of parents in giving their children vitamin D supplementation and its association with variables of the Theory of Planned Behaviour, moral and descriptive norms and habits. A cross-sectional survey to assess present supplementation-related behaviour, knowledge, received information, intention, attitude, subjective norm, perceived behavioural control, moral norm, descriptive norm and habit. Data obtained from a representative Internet Panel by means of electronic questionnaires. Parents (n 270) of children aged 0-4 years. Half of the parents (48.9 %) gave their child sufficient vitamin D supplementation. Giving the supplement at a fixed time, a positive intention and habit were significantly associated with actual behaviour. The higher age of the child, first-born status, a fixed time for taking vitamin supplementation, descriptive norm and moral obligation were significantly associated with intention. These results indicate that because many parents do not give their children adequate vitamin D supplementation, the promotion of supplementation during the first years of life is a necessity. Effective yet simple strategies should be developed, focused on improving moral obligation, descriptive norms and habit formation.

  1. Performance of Dutch children on the Bayley III: a comparison study of US and Dutch norms.

    PubMed

    Steenis, Leonie J P; Verhoeven, Marjolein; Hessen, Dave J; van Baar, Anneloes L

    2015-01-01

    The Bayley Scales of Infant and Toddler Development-third edition (Bayley-III) are frequently used to assess early child development worldwide. However, the original standardization only included US children, and it is still unclear whether or not these norms are adequate for use in other populations. Recently, norms for the Dutch version of the Bayley-III (The Bayley-III-NL) were made. Scores based on Dutch and US norms were compared to study the need for population-specific norms. Scaled scores based on Dutch and US norms were compared for 1912 children between 14 days and 42 months 14 days. Next, the proportions of children scoring < 1-SD and < -2 SD based on the two norms were compared, to identify over- or under-referral for developmental delay resulting from non-population-based norms. Scaled scores based on Dutch norms fluctuated around values based on US norms on all subtests. The extent of the deviations differed across ages and subtests. Differences in means were significant across all five subtests (p < .01) with small to large effect sizes (ηp2) ranging from .03 to .26). Using the US instead of Dutch norms resulted in over-referral regarding gross motor skills, and under-referral regarding cognitive, receptive communication, expressive communication, and fine motor skills. The Dutch norms differ from the US norms for all subtests and these differences are clinically relevant. Population specific norms are needed to identify children with low scores for referral and intervention, and to facilitate international comparisons of population data.

  2. Brain responses to social norms: Meta-analyses of fMRI studies.

    PubMed

    Zinchenko, Oksana; Arsalidou, Marie

    2018-02-01

    Social norms have a critical role in everyday decision-making, as frequent interaction with others regulates our behavior. Neuroimaging studies show that social-based and fairness-related decision-making activates an inconsistent set of areas, which sometimes includes the anterior insula, anterior cingulate cortex, and others lateral prefrontal cortices. Social-based decision-making is complex and variability in findings may be driven by socio-cognitive activities related to social norms. To distinguish among social-cognitive activities related to social norms, we identified 36 eligible articles in the functional magnetic resonance imaging (fMRI) literature, which we separate into two categories (a) social norm representation and (b) norm violations. The majority of original articles (>60%) used tasks associated with fairness norms and decision-making, such as ultimatum game, dictator game, or prisoner's dilemma; the rest used tasks associated to violation of moral norms, such as scenarios and sentences of moral depravity ratings. Using quantitative meta-analyses, we report common and distinct brain areas that show concordance as a function of category. Specifically, concordance in ventromedial prefrontal regions is distinct to social norm representation processing, whereas concordance in right insula, dorsolateral prefrontal, and dorsal cingulate cortices is distinct to norm violation processing. We propose a neurocognitive model of social norms for healthy adults, which could help guide future research in social norm compliance and mechanisms of its enforcement. © 2017 Wiley Periodicals, Inc.

  3. The relevance of moral norms in distinct relational contexts: Purity versus harm norms regulate self-directed actions

    PubMed Central

    Dungan, James A.; Chakroff, Alek; Young, Liane

    2017-01-01

    Recent efforts to partition the space of morality have focused on the descriptive content of distinct moral domains (e.g., harm versus purity), or alternatively, the relationship between the perpetrator and victim of moral violations. Across three studies, we demonstrate that harm and purity norms are relevant in distinct relational contexts. Moral judgments of purity violations, compared to harm violations, are relatively more sensitive to the negative impact perpetrators have on themselves versus other victims (Study 1). This pattern replicates across a wide array of harm and purity violations varying in severity (Studies 2 and 3). Moreover, while perceptions of harm predict moral judgment consistently across relational contexts, perceptions of purity predict moral judgment more for self-directed actions, where perpetrators violate themselves, compared to dyadic actions, where perpetrators violate other victims (Study 3). Together, these studies reveal how an action’s content and its relational context interact to influence moral judgment, providing novel insights into the adaptive functions of harm and purity norms. PMID:28278214

  4. Tutorial: Calculating Percentile Rank and Percentile Norms Using SPSS

    ERIC Educational Resources Information Center

    Baumgartner, Ted A.

    2009-01-01

    Practitioners can benefit from using norms, but they often have to develop their own percentile rank and percentile norms. This article is a tutorial on how to quickly and easily calculate percentile rank and percentile norms using SPSS, and this information is presented for a data set. Some issues in calculating percentile rank and percentile…

  5. Do L2 Writing Courses Affect the Improvement of L1 Writing Skills via Skills Transfer from L2 to L1?

    ERIC Educational Resources Information Center

    Gonca, Altmisdort

    2016-01-01

    This study investigates the relationship of second language (L2) writing skills proficiency with the first language (L1) writing skills, in light of the language transfer. The study aims to analyze the positive effects of L2 writing proficiency on L1 writing proficiency. Forty native Turkish-speaking university students participated in the study.…

  6. Prediction of minimal residual viremia in HCV type 1 infected patients receiving interferon-based therapy.

    PubMed

    Knop, Viola; Teuber, Gerlinde; Klinker, Hartwig; Möller, Bernd; Rasenack, Jens; Hinrichsen, Holger; Gerlach, Tilman; Spengler, Ulrich; Buggisch, Peter; Neumann, Konrad; Sarrazin, Christoph; Zeuzem, Stefan; Berg, Thomas

    2013-01-01

    Complete suppression of viral replication is crucial in chronic HCV treatment in order to prevent relapse and resistance development. We wanted to find out which factors influence the period from being already HCV RNA negative by bDNA assay (< 615 IU/mL) to become undetectable by the more sensitive TMA test (< 5.3 IU/mL). Evaluated were 433 HCV type 1-infected patients. All of them received 1.5 ug/kg Peg-IFNα-2b plus ribavirin for 18-48 weeks. bDNA was performed weekly during the first 8 weeks and thereafter at weeks 12, 24, and 48. Patients who became bDNA undetectable were additionally analysed by TMA. Of the 309 patients with on-treatment response (< 615 IU/mL), 289 also reached undetectable HCV RNA levels by TMA. Multivariate analysis revealed that viremia ≤ 400,000 IU/mL (p = 0.001), fast initial virologic decline (p = 0.004) and absence of fibrosis (p = 0.035) were independent predictors of an accelerated on-treatment response by TMA assay in already bDNA negative patients. bDNA negative patients becoming HCV RNA undetectable by TMA within the following 3 weeks had a frequency of relapse of 21%, whereas those showing TMA negativity after 3 weeks relapsed in 38% (p = 0.001). In RVR patients (bDNA < 615 IU/mL at week 4) the corresponding relapse rates were 15.3% vs. 37.5%, respectively (p = 0.003). Early viral kinetics, baseline viremia and fibrosis stage are important tools to predict persistent minimal viremia during interferon-based therapy. The data have implications for designing a more refined treatment strategy in HCV infection, even in the setting of protease inhibitor-based triple treatment.

  7. Hessian Schatten-norm regularization for linear inverse problems.

    PubMed

    Lefkimmiatis, Stamatios; Ward, John Paul; Unser, Michael

    2013-05-01

    We introduce a novel family of invariant, convex, and non-quadratic functionals that we employ to derive regularized solutions of ill-posed linear inverse imaging problems. The proposed regularizers involve the Schatten norms of the Hessian matrix, which are computed at every pixel of the image. They can be viewed as second-order extensions of the popular total-variation (TV) semi-norm since they satisfy the same invariance properties. Meanwhile, by taking advantage of second-order derivatives, they avoid the staircase effect, a common artifact of TV-based reconstructions, and perform well for a wide range of applications. To solve the corresponding optimization problems, we propose an algorithm that is based on a primal-dual formulation. A fundamental ingredient of this algorithm is the projection of matrices onto Schatten norm balls of arbitrary radius. This operation is performed efficiently based on a direct link we provide between vector projections onto lq norm balls and matrix projections onto Schatten norm balls. Finally, we demonstrate the effectiveness of the proposed methods through experimental results on several inverse imaging problems with real and simulated data.

  8. A latent class regression analysis of men's conformity to masculine norms and psychological distress.

    PubMed

    Wong, Y Joel; Owen, Jesse; Shea, Munyi

    2012-01-01

    How are specific dimensions of masculinity related to psychological distress in specific groups of men? To address this question, the authors used latent class regression to assess the optimal number of latent classes that explained differential relationships between conformity to masculine norms and psychological distress in a racially diverse sample of 223 men. The authors identified a 2-class solution. Both latent classes demonstrated very different associations between conformity to masculine norms and psychological distress. In Class 1 (labeled risk avoiders; n = 133), conformity to the masculine norm of risk-taking was negatively related to psychological distress. In Class 2 (labeled detached risk-takers; n = 90), conformity to the masculine norms of playboy, self-reliance, and risk-taking was positively related to psychological distress, whereas conformity to the masculine norm of violence was negatively related to psychological distress. A post hoc analysis revealed that younger men and Asian American men (compared with Latino and White American men) had significantly greater odds of being in Class 2 versus Class 1. The implications of these findings for future research and clinical practice are examined. (c) 2012 APA, all rights reserved.

  9. Using Facebook to deliver a social norm intervention to reduce problem drinking at university.

    PubMed

    Ridout, Brad; Campbell, Andrew

    2014-11-01

    University students usually overestimate peer alcohol use, resulting in them 'drinking up' to perceived norms. Social norms theory suggests correcting these inflated perceptions can reduce alcohol consumption. Recent findings by the current authors show portraying oneself as 'a drinker' is considered by many students to be a socially desirable component of their Facebook identity, perpetuating an online culture that normalises binge drinking. However, social networking sites have yet to be utilised in social norms interventions. Actual and perceived descriptive and injunctive drinking norms were collected from 244 university students. Ninety-five students screened positive for hazardous drinking and were randomly allocated to a control group or intervention group that received social norms feedback via personalised Facebook private messages over three sessions. At 1 month post-intervention, the quantity and frequency of alcohol consumed by intervention group during the previous month had significantly reduced compared with baseline and controls. Reductions were maintained 3 months post-intervention. Intervention group perceived drinking norms were significantly more accurate post-intervention. This is the first study to test the feasibility of using Facebook to deliver social norms interventions. Correcting misperceptions of peer drinking norms resulted in clinically significant reductions in alcohol use. Facebook has many advantages over traditional social norms delivery, providing an innovative method for tackling problem drinking at university. These results have implications for the use of Facebook to deliver positive messages about safe alcohol use to students, which may counter the negative messages regarding alcohol normally seen on Facebook. © 2014 Australasian Professional Society on Alcohol and other Drugs.

  10. Masculinity and HIV: Dimensions of Masculine Norms that Contribute to Men's HIV-Related Sexual Behaviors.

    PubMed

    Fleming, Paul J; DiClemente, Ralph J; Barrington, Clare

    2016-04-01

    Numerous studies have documented a relationship between masculine norms and men's HIV-related sexual behaviors, but intervening upon this relationship requires a nuanced understanding of the specific aspects of masculine norms that shape men's sexual behaviors. We integrate theories on masculinities with empirical HIV research to identify specific dimensions of masculine norms that influence men's HIV-related sexual behaviors. We identify three major dimensions of masculine norms that shape men's sexual behavior: (1) uncontrollable male sex drive, (2) capacity to perform sexually, and (3) power over others. While the existing literature does help explain the relationship between masculine norms and men's sexual behaviors several gaps remain including: a recognition of context-specific masculinities, an interrogation of the positive influences of masculinity, adoption of an intersectional approach, assessment of changes in norms and behaviors over time, and rigorous evaluations of gender-transformative approaches. Addressing these gaps in future research may optimize prevention efforts.

  11. Evaluating the implementation of RxNorm in ambulatory electronic prescriptions

    PubMed Central

    Ward-Charlerie, Stacy; Rupp, Michael T; Kilbourne, John; Amin, Vishal P; Ruiz, Joshua

    2016-01-01

    Objective RxNorm is a standardized drug nomenclature maintained by the National Library of Medicine that has been recommended as an alternative to the National Drug Code (NDC) terminology for use in electronic prescribing. The objective of this study was to evaluate the implementation of RxNorm in ambulatory care electronic prescriptions (e-prescriptions). Methods We analyzed a random sample of 49 997 e-prescriptions that were received by 7391 locations of a national retail pharmacy chain during a single day in April 2014. The e-prescriptions in the sample were generated by 37 801 ambulatory care prescribers using 519 different e-prescribing software applications. Results We found that 97.9% of e-prescriptions in the study sample could be accurately represented by an RxNorm identifier. However, RxNorm identifiers were actually used as drug identifiers in only 16 433 (33.0%) e-prescriptions. Another 431 (2.5%) e-prescriptions that used RxNorm identifiers had a discrepancy in the corresponding Drug Database Code qualifier field or did not have a qualifier (Term Type) at all. In 10 e-prescriptions (0.06%), the free-text drug description and the RxNorm concept unique identifier pointed to completely different drug concepts, and in 7 e-prescriptions (0.04%), the NDC and RxNorm drug identifiers pointed to completely different drug concepts. Discussion The National Library of Medicine continues to enhance the RxNorm terminology and expand its scope. This study illustrates the need for technology vendors to improve their implementation of RxNorm; doing so will accelerate the adoption of RxNorm as the preferred alternative to using the NDC terminology in e-prescribing. PMID:26510879

  12. Techniques for Computation of Frequency Limited H∞ Norm

    NASA Astrophysics Data System (ADS)

    Haider, Shafiq; Ghafoor, Abdul; Imran, Muhammad; Fahad Mumtaz, Malik

    2018-01-01

    Traditional H ∞ norm depicts peak system gain over infinite frequency range, but many applications like filter design, model order reduction and controller design etc. require computation of peak system gain over specific frequency interval rather than infinite range. In present work, new computationally efficient techniques for computation of H ∞ norm over frequency limited interval are proposed. Proposed techniques link norm computation with maximum singular value of the system in limited frequency interval. Numerical examples are incorporated to validate the proposed concept.

  13. Four year-olds use norm-based coding for face identity.

    PubMed

    Jeffery, Linda; Read, Ainsley; Rhodes, Gillian

    2013-05-01

    Norm-based coding, in which faces are coded as deviations from an average face, is an efficient way of coding visual patterns that share a common structure and must be distinguished by subtle variations that define individuals. Adults and school-aged children use norm-based coding for face identity but it is not yet known if pre-school aged children also use norm-based coding. We reasoned that the transition to school could be critical in developing a norm-based system because school places new demands on children's face identification skills and substantially increases experience with faces. Consistent with this view, face identification performance improves steeply between ages 4 and 7. We used face identity aftereffects to test whether norm-based coding emerges between these ages. We found that 4 year-old children, like adults, showed larger face identity aftereffects for adaptors far from the average than for adaptors closer to the average, consistent with use of norm-based coding. We conclude that experience prior to age 4 is sufficient to develop a norm-based face-space and that failure to use norm-based coding cannot explain 4 year-old children's poor face identification skills. Copyright © 2013 Elsevier B.V. All rights reserved.

  14. Norms and practices within marriage which shape gender roles, HIV/AIDS risk and risk reduction strategies in Cabo Delgado, Mozambique.

    PubMed

    Bandali, S

    2011-09-01

    Despite increasing HIV/AIDS rates among married individuals, minimal research has been conducted on how men and women respond to risk in a marriage. This paper examines strategies used by married individuals to combat HIV/AIDS risk against prevailing gender norms. Qualitative data were gathered in four villages of Cabo Delgado province, Mozambique. Group discussions were held with 160 men and women to explore gender norms, HIV/AIDS knowledge and risk determinants. From the group discussions, 29 individuals were selected for further in-depth interviews to explore relationships between gender norms and risk reduction efforts within marriages. Findings illustrate how infidelity and social limitations placed on condom use not only increase HIV/AIDS risk but also entrench gender disparities. Although power differences between genders can make it difficult to negotiate safe sex, men and women are taking measures to reduce perceived HIV/AIDS risk in their marriage. Married men are reconstructing norms and taking responsibility to protect their family from HIV/AIDS by remaining faithful. For women, responses to HIV/AIDS risk in a marriage are more closely related to their ability to generate an income. Financially dependent women tend to leave a risky marriage altogether in contrast to financially autonomous women who will negotiate condom use with their husband. Factors such as experience with a risky partner, the desire to maintain a good social standing, fear of HIV/AIDS acquisition and parental guidance and support influence men and women to reduce perceived HIV/AIDS risk, despite constraining gender norms and power imbalances in a marriage. Nuanced understandings of the ways in which men and women are already taking measures to decrease noted HIV/AIDS risk, despite gender norms that make this a challenge, should be incorporated into localised responses.

  15. Ethnic diversity, traditional norms, and marriage behaviour in Indonesia.

    PubMed

    Buttenheim, Alison M; Nobles, Jenna

    2009-11-01

    What role do cultural norms play in shaping individual behaviour and how does this relationship change with rapid socio-economic development? While modernization and convergence theories predict a weakened relationship between culture and behaviour as individuals rely less on family and community members for economic opportunities, recent research suggests that such norms can persist and continue to influence behaviour. We explored this question for Indonesia, asking whether cultural norms for age at marriage and post-marriage residence-as embodied in local ethnicity-based laws and customs known as 'adat'-relate to actual marriage behaviour. We demonstrate that adat norms are strong predictors of marriage behaviour, both over time and net of large increases in educational attainment. Our results suggest more generally that traditional marriage norms can persist even when a society is in the process of rapid socio-economic development.

  16. Mortality salience increases personal relevance of the norm of reciprocity.

    PubMed

    Schindler, Simon; Reinhard, Marc-André; Stahlberg, Dagmar

    2012-10-01

    Research on terror management theory found evidence that people under mortality salience strive to live up to salient cultural norms and values, like egalitarianism, pacifism, or helpfulness. A basic, strongly internalized norm in most human societies is the norm of reciprocity: people should support those who supported them (i.e., positive reciprocity), and people should injure those who injured them (i.e., negative reciprocity), respectively. In an experiment (N = 98; 47 women, 51 men), mortality salience overall significantly increased personal relevance of the norm of reciprocity (M = 4.45, SD = 0.65) compared to a control condition (M = 4.19, SD = 0.59). Specifically, under mortality salience there was higher motivation to punish those who treated them unfavourably (negative norm of reciprocity). Unexpectedly, relevance of the norm of positive reciprocity remained unaffected by mortality salience. Implications and limitations are discussed.

  17. Vitamin D supplement consumption is required to achieve a minimal target 25-hydroxyvitamin D concentration of > or = 75 nmol/L in older people.

    PubMed

    Baraké, Roula; Weiler, Hope; Payette, Hélène; Gray-Donald, Katherine

    2010-03-01

    Population level data on how older individuals living at high latitudes achieve optimal vitamin D status are not fully explored. Our objective was to examine the intake of vitamin D among healthy older individuals with 25-hydroxyvitamin D [25(OH)D] concentrations > or =75 nmol/L and to describe current sources of dietary vitamin D. We conducted a population-based, cross-sectional study of 404 healthy men and women aged 69 to 83 y randomly selected from the NuAge longitudinal study in Québec, Canada. Dietary intakes were assessed by 6 24-h recalls. We examined the contribution of foods and vitamin/mineral supplements to vitamin D intake. Serum 25(OH)D was assessed by RIA. We assessed smoking status, season of 25(OH)D measurement, physical activity, and anthropometric and sociodemographic variables. Vitamin D status was distributed as follows: 7% (<37.5 nmol/L), 48% (37.5-74.9 nmol/L), and 45% (> or = 75 nmol/L). Vitamin D intake from supplements varied across the 3 vitamin D status groups: 0.5, 4.1, and 8.9 microg/d, respectively (P < 0.0001). Adding food sources, these total intakes were 4.6, 8.7, and 14.1 microg/d, respectively. In multivariate analysis, vitamin D from foods and supplements and by season was associated with vitamin D status. These healthy, community-dwelling older men and women with 25(OH)D concentrations >75 nmol/L had mean intakes of 14.1 microg/d from food and supplements. Supplement use is an important contributor to achieve a minimal target of 25(OH)D concentration > or = 75 nmol/L.

  18. Predicting Australian adults' sun-safe behaviour: examining the role of personal and social norms.

    PubMed

    White, Katherine M; Starfelt, Louise C; Young, Ross McD; Hawkes, Anna L; Leske, Stuart; Hamilton, Kyra

    2015-05-01

    To address the scarcity of comprehensive, theory-based research in the Australian context, this study, using a theory of planned behaviour (TPB) framework, investigated the role of personal and social norms to identify the key predictors of adult Australians' sun-safe intentions and behaviour. The study used a prospective design with two waves of data collection, 1 week apart. Participants were 816 adults (48.2% men) aged between 18 and 88 years recruited from urban, regional, and rural areas of Australia. At baseline, participants completed a questionnaire assessing the standard TPB predictors (attitude, subjective norm, and perceived behavioural control [PBC]), past behaviour, behavioural intention, and additional measures of group norm for the referent groups of friends and family, image norm, personal norm, personal choice/responsibility, and Australian identity. Seventy-one per cent of the participants (n = 577) reported on their sun-safe behaviour in the subsequent week. Via path modelling, past behaviour, attitude, group norm (friends), personal norm, and personal choice/responsibility emerged as independent predictors of intentions which, in turn, predicted sun-safe behaviour prospectively. Past behaviour, but not PBC, had direct effects on sun-safe behaviour. The model explained 61.6% and 43.9% of the variance in intention and behaviour, respectively. This study provides support for the use of a comprehensive theoretical decision-making model to explain Australian adults' sun-safe intentions and behaviours and identifies viable targets for health-promoting messages in this high-risk context. Statement of contribution What is already known on this subject? Identifying determinants of sun-safe behaviour is vital in high-risk cancer areas like Australia. For young Australians, friendship group norm is a key influence of intentions and behaviour. Little is known about drivers of sun safety, especially norms, among Australian adults in general. What does this

  19. Prosocial norms as a positive youth development construct: a conceptual review.

    PubMed

    Siu, Andrew M H; Shek, Daniel T L; Law, Ben

    2012-01-01

    Prosocial norms like reciprocity, social responsibility, altruism, and volunteerism are ethical standards and beliefs that youth development programs often want to promote. This paper reviews evolutionary, social-cognitive, and developmental theories of prosocial development and analyzes how young people learn and adopt prosocial norms. The paper showed that very few current theories explicitly address the issue of how prosocial norms, in form of feelings of moral obligations, may be challenged by a norm of self-interest and social circumstances when prosocial acts are needed. It is necessary to develop theories which put prosocial norms as a central construct, and a new social cognitive theory of norm activation has the potential to help us understand how prosocial norms may be applied. This paper also highlights how little we know about young people perceiving and receiving prosocial norms and how influential of school policies and peer influence on the prosocial development. Lastly, while training of interpersonal competence (e.g., empathy, moral reasoning, etc.) was commonly used in the youth development, their effectiveness was not systematically evaluated. It will also be interesting to examine how computer and information technology or video games may be used in e-learning of prosocial norms.

  20. Not just the norm: exemplar-based models also predict face aftereffects.

    PubMed

    Ross, David A; Deroche, Mickael; Palmeri, Thomas J

    2014-02-01

    The face recognition literature has considered two competing accounts of how faces are represented within the visual system: Exemplar-based models assume that faces are represented via their similarity to exemplars of previously experienced faces, while norm-based models assume that faces are represented with respect to their deviation from an average face, or norm. Face identity aftereffects have been taken as compelling evidence in favor of a norm-based account over an exemplar-based account. After a relatively brief period of adaptation to an adaptor face, the perceived identity of a test face is shifted toward a face with attributes opposite to those of the adaptor, suggesting an explicit psychological representation of the norm. Surprisingly, despite near universal recognition that face identity aftereffects imply norm-based coding, there have been no published attempts to simulate the predictions of norm- and exemplar-based models in face adaptation paradigms. Here, we implemented and tested variations of norm and exemplar models. Contrary to common claims, our simulations revealed that both an exemplar-based model and a version of a two-pool norm-based model, but not a traditional norm-based model, predict face identity aftereffects following face adaptation.

  1. Not Just the Norm: Exemplar-Based Models also Predict Face Aftereffects

    PubMed Central

    Ross, David A.; Deroche, Mickael; Palmeri, Thomas J.

    2014-01-01

    The face recognition literature has considered two competing accounts of how faces are represented within the visual system: Exemplar-based models assume that faces are represented via their similarity to exemplars of previously experienced faces, while norm-based models assume that faces are represented with respect to their deviation from an average face, or norm. Face identity aftereffects have been taken as compelling evidence in favor of a norm-based account over an exemplar-based account. After a relatively brief period of adaptation to an adaptor face, the perceived identity of a test face is shifted towards a face with opposite attributes to the adaptor, suggesting an explicit psychological representation of the norm. Surprisingly, despite near universal recognition that face identity aftereffects imply norm-based coding, there have been no published attempts to simulate the predictions of norm- and exemplar-based models in face adaptation paradigms. Here we implemented and tested variations of norm and exemplar models. Contrary to common claims, our simulations revealed that both an exemplar-based model and a version of a two-pool norm-based model, but not a traditional norm-based model, predict face identity aftereffects following face adaptation. PMID:23690282

  2. CLEX: A Cross-Linguistic Lexical Norms Database

    ERIC Educational Resources Information Center

    Jorgensen, Rune Norgaard; Dale, Philip S.; Bleses, Dorthe; Fenson, Larry

    2010-01-01

    Parent report has proven a valid and cost-effective means of evaluating early child language. Norming datasets for these instruments, which provide the basis for standardized comparisons of individual children to a population, can also be used to derive norms for the acquisition of individual words in production and comprehension and also early…

  3. PD-1/PD-L1, but not PD-1/PD-L2, interactions regulate the severity of experimental autoimmune encephalomyelitis.

    PubMed

    Carter, Laura L; Leach, Michael W; Azoitei, Mihai L; Cui, Junqing; Pelker, Jeffrey W; Jussif, Jason; Benoit, Steve; Ireland, Gretchen; Luxenberg, Deborah; Askew, G Roger; Milarski, Kim L; Groves, Christopher; Brown, Tom; Carito, Brenda A; Percival, Karen; Carreno, Beatriz M; Collins, Mary; Marusic, Suzana

    2007-01-01

    Interactions between PD-1 and its two differentially expressed ligands, PD-L1 and PD-L2, attenuate T cell activation and effector function. To determine the role of these molecules in autoimmune disease of the CNS, PD-1-/-, PD-L1-/- and PD-L2-/- mice were generated and immunized to induce experimental autoimmune encephalomyelitis (EAE). PD-1-/- and PD-L1-/- mice developed more severe EAE than wild type and PD-L2-/- mice. Consistent with this, PD-1-/- and PD-L1-/- cells produced elevated levels of the pro-inflammatory cytokines IFN-gamma, TNF, IL-6 and IL-17. These results demonstrate that interactions between PD-1/PD-L1, but not PD-1/PDL-2, are crucial in attenuating T cell responses in EAE.

  4. Alcohol evaluations and acceptability: Examining descriptive and injunctive norms among heavy drinkers

    PubMed Central

    Foster, Dawn W.; Neighbors, Clayton; Krieger, Heather

    2015-01-01

    Objectives This study assessed descriptive and injunctive norms, evaluations of alcohol consequences, and acceptability of drinking. Methods Participants were 248 heavy-drinking undergraduates (81.05% female; Mage = 23.45). Results Stronger perceptions of descriptive and injunctive norms for drinking and more positive evaluations of alcohol consequences were positively associated with drinking and the number of drinks considered acceptable. Descriptive and injunctive norms interacted, indicating that injunctive norms were linked with number of acceptable drinks among those with higher descriptive norms. Descriptive norms and evaluations of consequences interacted, indicating that descriptive norms were positively linked with number of acceptable drinks among those with negative evaluations of consequences; however, among those with positive evaluations of consequences, descriptive norms were negatively associated with number of acceptable drinks. Injunctive norms and evaluations of consequences interacted, indicating that injunctive norms were positively associated with number of acceptable drinks, particularly among those with positive evaluations of consequences. A three-way interaction emerged between injunctive and descriptive norms and evaluations of consequences, suggesting that injunctive norms and the number of acceptable drinks were positively associated more strongly among those with negative versus positive evaluations of consequences. Those with higher acceptable drinks also had positive evaluations of consequences and were high in injunctive norms. Conclusions Findings supported hypotheses that norms and evaluations of alcohol consequences would interact with respect to drinking and acceptance of drinking. These examinations have practical utility and may inform development and implementation of interventions and programs targeting alcohol misuse among heavy drinking undergraduates. PMID:25437265

  5. Minimal modification of tri-bimaximal neutrino mixing and leptonic CP violation

    NASA Astrophysics Data System (ADS)

    Kang, Sin Kyu

    2017-12-01

    We confront possible forms of the minimal modification of the tri-bimaximal (TBM) neutrino mixing matrix proposed by Kang and Kim (Phys. Rev. D 90, 077301 (2014)) with the latest global fit to neutrino data. One form among them is singled out by the current experimental results at 1σ confidence level (C.L.) The minimal modification of the TBM mixing matrix makes possible the prediction of Dirac-type CP phase in the Pontecorbo-Maki-Nakagawa-Sakata neutrino mixing matrix in terms of two neutrino mixing angles. By carrying out a numerical analysis based on the latest experimental results for neutrino mixing angles, we are able to present new results on the prediction of the Dirac-type CP phase. We also compare our results on CP violation with those from the current global fit at 1 σ C.L.

  6. “Who Doesn’t?”—The Impact of Descriptive Norms on Corruption

    PubMed Central

    Köbis, Nils C.; van Prooijen, Jan-Willem; Righetti, Francesca; Van Lange, Paul A. M.

    2015-01-01

    Corruption poses one of the major societal challenges of our time. Considerable advances have been made in understanding corruption on a macro level, yet the psychological antecedents of corrupt behavior remain largely unknown. In order to explain why some people engage in corruption while others do not, we explored the impact of descriptive social norms on corrupt behavior by using a novel behavioral measure of corruption. We conducted three studies to test whether perceived descriptive norms of corruption (i.e. the belief about the prevalence of corruption in a specific context) influence corrupt behavior. The results indicated that descriptive norms highly correlate with corrupt behavior—both when measured before (Study 1) or after (Study 2) the behavioral measure of corruption. Finally, we adopted an experimental design to investigate the causal effect of descriptive norms on corruption (Study 3). Corrupt behavior in the corruption game significantly drops when participants receive short anti-corruption descriptive norm primes prior to the game. These findings indicate that perceived descriptive norms can impact corrupt behavior and, possibly, could offer an explanation for inter-personal and inter-cultural variation in corrupt behavior in the real world. We discuss implications of these findings and draw avenues for future research. PMID:26121127

  7. Changing Norms to Change Behavior.

    PubMed

    Miller, Dale T; Prentice, Deborah A

    2016-01-01

    Providing people with information about the behavior and attitudes of their peers is a strategy commonly employed by those seeking to reduce behavior deemed harmful either to individuals (e.g., high alcohol consumption) or the collective (e.g., high energy consumption). We review norm-based interventions, detailing the logic behind them and the various forms they can take. We give special attention to interventions designed to decrease college students' drinking and increase environment-friendly behaviors. We identify the conditions under which norm information has the highest likelihood of changing the targeted behavior and discuss why this is the case.

  8. Social norms and women's risk of intimate partner violence in Nepal.

    PubMed

    Clark, Cari Jo; Ferguson, Gemma; Shrestha, Binita; Shrestha, Prabin Nanicha; Oakes, J Michael; Gupta, Jhumka; McGhee, Susi; Cheong, Yuk Fai; Yount, Kathryn M

    2018-04-01

    Social norms increasingly are the focus of intimate partner violence (IPV) prevention strategies but are among the least examined contextual factors in quantitative violence research. This study assesses the within-community, between-community, and contextual effect of a new measure of social norms (PVNS: Partner Violence Norms Scale) on women's risk of IPV. Data come from baseline surveys collected from 1435 female, married, reproductive-age participants, residing in 72 wards in three districts (Chitwan, Kapilvastu, Nawalparasi) in Nepal who were enrolled in a cluster randomized trial testing the impact of a social behavioral change communication intervention designed to prevent IPV. Results of unconditional multilevel logistic regression models indicated that there was cluster-level variability in the 12-month prevalence of physical (ICC = 0.07) and sexual (ICC = 0.05) IPV. Mean PVNS scores also varied across wards. When modeled simultaneously, PVNS scores aggregated to the ward-level and at the individual-level were associated with higher odds of physical (OR ind  = 1.12, CI = 1.04, 1.20; OR ward  = 1.40, CI = 1.15, 1.72) and sexual (OR ind  = 1.15, CI = 1.08, 1.24; OR ward  = 1.47, CI = 1.24, 1.74) IPV. The contextual effect was significant in the physical (0.23, se = 0.11, t = 2.12) and sexual (0.24, se = 0.09, t = 2.64) IPV models, suggesting that the ward-level association was larger than that at the individual-level. Adjustment for covariates slightly attenuated the ward-level association and eliminated the contextual association, suggesting that individual perceptions and the collective community phenomena were equally strong predictors of women's risk of IPV and should be taken into consideration when planning interventions. PVNS is a promising measure of social norms underpinning women's risk of IPV and warrants further psychometric testing. Copyright © 2018 The Authors. Published by Elsevier Ltd

  9. Semantic memory: a feature-based analysis and new norms for Italian.

    PubMed

    Montefinese, Maria; Ambrosini, Ettore; Fairfield, Beth; Mammarella, Nicola

    2013-06-01

    Semantic norms for properties produced by native speakers are valuable tools for researchers interested in the structure of semantic memory and in category-specific semantic deficits in individuals following brain damage. The aims of this study were threefold. First, we sought to extend existing semantic norms by adopting an empirical approach to category (Exp. 1) and concept (Exp. 2) selection, in order to obtain a more representative set of semantic memory features. Second, we extensively outlined a new set of semantic production norms collected from Italian native speakers for 120 artifactual and natural basic-level concepts, using numerous measures and statistics following a feature-listing task (Exp. 3b). Finally, we aimed to create a new publicly accessible database, since only a few existing databases are publicly available online.

  10. Deference in Indians' decision making: introjected goals or injunctive norms?

    PubMed

    Savani, Krishna; Morris, Michael W; Naidu, N V R

    2012-04-01

    We examine the claim that Indians are more likely than Americans to act deferentially in the presence of authority figures and explore 2 possible psychological mechanisms for this cultural difference: introjected goals and injunctive norms. Studies 1 and 2 showed that after reflecting upon an authority's expectations, Indians were more likely than Americans to make clothing and course choices consistent with the authority's expectations, but there was no such cultural difference for peers' expectations. Study 3 showed that merely activating the concept of authority figures, without highlighting specific expectations, was sufficient to influence Indians' choices but not their evaluations. Examining a more basic distinction underlying introjected goals versus injunctive norms, Study 4 showed that authority primes influenced Indians' sense of what they should do but not what they want to do. Study 5 showed that, inconsistent with the internalized goal mechanism, the effect of explicit authority primes did not increase after brief delays. However, Indian participants who were less likely to accommodate to the salient authority experienced more guilt across delay conditions, which supported the injunctive norms mechanism. The findings suggest that manipulating injunctive norms can be an effective means for inducing or eliminating deferential behaviors in Indian settings. (c) 2012 APA, all rights reserved.

  11. Do L1 Reading Achievement and L1 Print Exposure Contribute to the Prediction of L2 Proficiency?

    ERIC Educational Resources Information Center

    Sparks, Richard L.; Patton, Jon; Ganschow, Leonore; Humbach, Nancy

    2012-01-01

    The study examined whether individual differences in high school first language (L1) reading achievement and print exposure would account for unique variance in second language (L2) written (word decoding, spelling, writing, reading comprehension) and oral (listening/speaking) proficiency after adjusting for the effects of early L1 literacy and…

  12. Minimal clinically important improvement (MCII) and patient-acceptable symptom state (PASS) in total hip arthroplasty (THA) patients 1 year postoperatively

    PubMed Central

    Paulsen, Aksel

    2014-01-01

    Background and purpose The increased use of patient-reported outcomes (PROs) in orthopedics requires data on estimated minimal clinically important improvements (MCIIs) and patient-acceptable symptom states (PASSs). We wanted to find cut-points corresponding to minimal clinically important PRO change score and the acceptable postoperative PRO score, by estimating MCII and PASS 1 year after total hip arthroplasty (THA) for the Hip Dysfunction and Osteoarthritis Outcome Score (HOOS) and the EQ-5D. Patients and methods THA patients from 16 different departments received 2 PROs and additional questions preoperatively and 1 year postoperatively. The PROs included were the HOOS subscales pain (HOOS Pain), physical function short form (HOOS-PS), and hip-related quality of life (HOOS QoL), and the EQ-5D. MCII and PASS were estimated using multiple anchor-based approaches. Results Of 1,837 patients available, 1,335 answered the preoperative PROs, and 1,288 of them answered the 1-year follow-up. The MCIIs and PASSs were estimated to be: 24 and 91 (HOOS Pain), 23 and 88 (HOOS-PS), 17 and 83 (HOOS QoL), 0.31 and 0.92 (EQ-5D Index), and 23 and 85 (EQ-VAS), respectively. MCIIs corresponded to a 38–55% improvement from mean baseline PRO score and PASSs corresponded to absolute follow-up scores of 57–91% of the maximum score in THA patients 1 year after surgery. Interpretation This study improves the interpretability of PRO scores. The different estimation approaches presented may serve as a guide for future MCII and PASS estimations in other contexts. The cutoff points may serve as reference values in registry settings. PMID:24286564

  13. Exact recovery of sparse multiple measurement vectors by [Formula: see text]-minimization.

    PubMed

    Wang, Changlong; Peng, Jigen

    2018-01-01

    The joint sparse recovery problem is a generalization of the single measurement vector problem widely studied in compressed sensing. It aims to recover a set of jointly sparse vectors, i.e., those that have nonzero entries concentrated at a common location. Meanwhile [Formula: see text]-minimization subject to matrixes is widely used in a large number of algorithms designed for this problem, i.e., [Formula: see text]-minimization [Formula: see text] Therefore the main contribution in this paper is two theoretical results about this technique. The first one is proving that in every multiple system of linear equations there exists a constant [Formula: see text] such that the original unique sparse solution also can be recovered from a minimization in [Formula: see text] quasi-norm subject to matrixes whenever [Formula: see text]. The other one is showing an analytic expression of such [Formula: see text]. Finally, we display the results of one example to confirm the validity of our conclusions, and we use some numerical experiments to show that we increase the efficiency of these algorithms designed for [Formula: see text]-minimization by using our results.

  14. Adults' Attitudes about Children's Gender Norm Transgressions.

    ERIC Educational Resources Information Center

    Blakemore, Judith E. Owen

    This study examined college students' knowledge and attitudes regarding children's gender, and social and moral norms, and compared their evaluations of violation of each norm type. Participating were 140 female and 67 male college students ranging in age from 17 to 46 years, 33 of whom were parents. Subjects were asked questions related to toys,…

  15. Effects of perceived descriptive norms on corrupt intention: The mediating role of moral disengagement.

    PubMed

    Zhao, Huanhuan; Zhang, Heyun; Xu, Yan

    2017-01-31

    The present study attempts to examine the effect of perceived descriptive norms on corrupt intention (e.g., bribe-taking intention) and then further explore the psychological mechanism underlying this effect. Based on social cognitive theory, we established a mediation model in which moral disengagement partially mediated the link between perceived descriptive norms and corrupt intention. In Study 1, participants (N = 690) completed a series of questionnaires, and the results demonstrated that, while perceived descriptive norms were positively associated with corrupt intention, it was partially mediated by moral disengagement. In Study 2, we conducted a priming experiment (N = 161) to test the causal relationship and psychological mechanism between perceived descriptive norms and corrupt intention. The results revealed that perceived descriptive norms triggered the propensity of individuals to morally disengage, which in turn, partially increased their corrupt intention. This study not only extends previous research by providing evidence that moral disengagement may be one of the reasons why perceived descriptive norms facilitate corrupt intention, but also suggests that reshaping normative beliefs and preventing the moral disengagement of individuals may be the effective ways to curb corrupt behaviours. © 2017 International Union of Psychological Science.

  16. Positive Community Norm Survey 2011 : Methodology and Results

    DOT National Transportation Integrated Search

    2012-09-01

    This survey established a baseline understanding of the positive norms that exist in Idaho, plus reveal the gaps in knowledge and perceived norms with regard to impaired driving. These gaps will indicate the most effective opportunities for future co...

  17. Positive Community Norm Survey 2011: Methodology and Results

    DOT National Transportation Integrated Search

    2012-09-01

    This survey established a baseline understanding of the positive norms that exist in Idaho, plus reveal the gaps in knowledge and perceived norms with regard to impaired driving. These gaps will indicate the most effective opportunities for future co...

  18. Prosocial Norms as a Positive Youth Development Construct: A Conceptual Review

    PubMed Central

    Siu, Andrew M. H.; Shek, Daniel T. L.; Law, Ben

    2012-01-01

    Prosocial norms like reciprocity, social responsibility, altruism, and volunteerism are ethical standards and beliefs that youth development programs often want to promote. This paper reviews evolutionary, social-cognitive, and developmental theories of prosocial development and analyzes how young people learn and adopt prosocial norms. The paper showed that very few current theories explicitly address the issue of how prosocial norms, in form of feelings of moral obligations, may be challenged by a norm of self-interest and social circumstances when prosocial acts are needed. It is necessary to develop theories which put prosocial norms as a central construct, and a new social cognitive theory of norm activation has the potential to help us understand how prosocial norms may be applied. This paper also highlights how little we know about young people perceiving and receiving prosocial norms and how influential of school policies and peer influence on the prosocial development. Lastly, while training of interpersonal competence (e.g., empathy, moral reasoning, etc.) was commonly used in the youth development, their effectiveness was not systematically evaluated. It will also be interesting to examine how computer and information technology or video games may be used in e-learning of prosocial norms. PMID:22666157

  19. L1 to Teach L2: Complexities and Contradictions

    ERIC Educational Resources Information Center

    Copland, Fiona; Neokleous, Georgios

    2011-01-01

    This article uncovers the complexities and contradictions inherent in making decisions about L1 use in the English language classroom. Through an analysis of data from classrooms in a Cypriot context and from interviews with Cypriot teachers, a number of functions for L1 use are identified, as are the teachers' rationales for using L1 for…

  20. [MINIMALLY INVASIVE PROCEDURE FOR CORRECTION OF PECTUS CARINATUM].

    PubMed

    Xu, Bing; Liu, Wenying

    2015-04-01

    To explore the method and experience in correction of pectus carinatum with minimally invasive procedure. Between June 2010 and January 2014, 30 patients with pectus carinatum were corrected by minimally invasive procedure. There were 21 boys and 9 girls whose average age was 13 years and 2 months (range, from 8 years and 10 months to 18 years and 9 months), including 24 cases of first operation, 2 recurrence after traditional pectus carinatum correction, and 4 cases secondary to median thoracotomy. Thirty patients had symmetric and asymmetric mild pectus carinatum. The operation was performed successfully in all patients, and no severe complication occurred. The operation time was 42-95 minutes (mean, 70 minutes). The bleeding volume during operation was 4-30 mL (mean, 10 mL). The time from operation to discharge was 6-10 days (mean, 7 days). The average time of follow-up was 25 months (range, 9-54 months). All surgical wound healed primarily with no infection. The X-ray films showed slight pneumothorax in 7 cases, and it was absorbed after 1 month without treatment. Loosening of internal fixation was found in 1 patient because of trauma at 6 months, and operation was performed again. The bar was removed at 2 years in 21 patients. The patients had good thoracic contour and normal activity. Minimally invasive procedure for correction of pectus carinatum is safe and will get satisfactory effect in maintaining thoracic contour. It has also less trauma and shorter operation time.

  1. The Social Norms of Suicidal and Self-Harming Behaviours in Scottish Adolescents.

    PubMed

    Quigley, Jody; Rasmussen, Susan; McAlaney, John

    2017-03-15

    Although the suicidal and self-harming behaviour of individuals is often associated with similar behaviours in people they know, little is known about the impact of perceived social norms on those behaviours. In a range of other behavioural domains (e.g., alcohol consumption, smoking, eating behaviours) perceived social norms have been found to strongly predict individuals' engagement in those behaviours, although discrepancies often exist between perceived and reported norms. Interventions which align perceived norms more closely with reported norms have been effective in reducing damaging behaviours. The current study aimed to explore whether the Social Norms Approach is applicable to suicidal and self-harming behaviours in adolescents. Participants were 456 pupils from five Scottish high-schools (53% female, mean age = 14.98 years), who completed anonymous, cross-sectional surveys examining reported and perceived norms around suicidal and self-harming behaviour. Friedman's ANOVA with post-hoc Wilcoxen signed-ranks tests indicated that proximal groups were perceived as less likely to engage in or be permissive of suicidal and self-harming behaviours than participants' reported themselves, whilst distal groups tended towards being perceived as more likely to do so. Binary logistic regression analyses identified a number of perceived norms associated with reported norms, with close friends' norms positively associated with all outcome variables. The Social Norms Approach may be applicable to suicidal and self-harming behaviour, but associations between perceived and reported norms and predictors of reported norms differ to those found in other behavioural domains. Theoretical and practical implications of the findings are considered.

  2. The Social Norms of Suicidal and Self-Harming Behaviours in Scottish Adolescents

    PubMed Central

    Quigley, Jody; Rasmussen, Susan; McAlaney, John

    2017-01-01

    Although the suicidal and self-harming behaviour of individuals is often associated with similar behaviours in people they know, little is known about the impact of perceived social norms on those behaviours. In a range of other behavioural domains (e.g., alcohol consumption, smoking, eating behaviours) perceived social norms have been found to strongly predict individuals’ engagement in those behaviours, although discrepancies often exist between perceived and reported norms. Interventions which align perceived norms more closely with reported norms have been effective in reducing damaging behaviours. The current study aimed to explore whether the Social Norms Approach is applicable to suicidal and self-harming behaviours in adolescents. Participants were 456 pupils from five Scottish high-schools (53% female, mean age = 14.98 years), who completed anonymous, cross-sectional surveys examining reported and perceived norms around suicidal and self-harming behaviour. Friedman’s ANOVA with post-hoc Wilcoxen signed-ranks tests indicated that proximal groups were perceived as less likely to engage in or be permissive of suicidal and self-harming behaviours than participants’ reported themselves, whilst distal groups tended towards being perceived as more likely to do so. Binary logistic regression analyses identified a number of perceived norms associated with reported norms, with close friends’ norms positively associated with all outcome variables. The Social Norms Approach may be applicable to suicidal and self-harming behaviour, but associations between perceived and reported norms and predictors of reported norms differ to those found in other behavioural domains. Theoretical and practical implications of the findings are considered. PMID:28294999

  3. When is best-worst best? A comparison of best-worst scaling, numeric estimation, and rating scales for collection of semantic norms.

    PubMed

    Hollis, Geoff; Westbury, Chris

    2018-02-01

    Large-scale semantic norms have become both prevalent and influential in recent psycholinguistic research. However, little attention has been directed towards understanding the methodological best practices of such norm collection efforts. We compared the quality of semantic norms obtained through rating scales, numeric estimation, and a less commonly used judgment format called best-worst scaling. We found that best-worst scaling usually produces norms with higher predictive validities than other response formats, and does so requiring less data to be collected overall. We also found evidence that the various response formats may be producing qualitatively, rather than just quantitatively, different data. This raises the issue of potential response format bias, which has not been addressed by previous efforts to collect semantic norms, likely because of previous reliance on a single type of response format for a single type of semantic judgment. We have made available software for creating best-worst stimuli and scoring best-worst data. We also made available new norms for age of acquisition, valence, arousal, and concreteness collected using best-worst scaling. These norms include entries for 1,040 words, of which 1,034 are also contained in the ANEW norms (Bradley & Lang, Affective norms for English words (ANEW): Instruction manual and affective ratings (pp. 1-45). Technical report C-1, the center for research in psychophysiology, University of Florida, 1999).

  4. Computational Substrates of Social Norm Enforcement by Unaffected Third Parties

    PubMed Central

    Zhong, Songfa; Chark, Robin; Hsu, Ming; Chew, Soo Hong

    2016-01-01

    Enforcement of social norms by impartial bystanders in the human species reveals a possibly unique capacity to sense and to enforce norms from a third party perspective. Such behavior, however, cannot be accounted by current computational models based on an egocentric notion of norms. Here, using a combination of model-based fMRI and third party punishment games, we show that brain regions previously implicated in egocentric norm enforcement critically extend to the important case of norm enforcement by unaffected third parties. Specifically, we found that responses in the ACC and insula cortex were positively associated with detection of distributional inequity, while those in the anterior DLPFC were associated with assessment of intentionality to the violator. Moreover, during sanction decisions, the subjective value of sanctions modulated activity in both vmPFC and rTPJ. These results shed light on the neurocomputational underpinnings of third party punishment and evolutionary origin of human norm enforcement. PMID:26825438

  5. Computational substrates of social norm enforcement by unaffected third parties.

    PubMed

    Zhong, Songfa; Chark, Robin; Hsu, Ming; Chew, Soo Hong

    2016-04-01

    Enforcement of social norms by impartial bystanders in the human species reveals a possibly unique capacity to sense and to enforce norms from a third party perspective. Such behavior, however, cannot be accounted by current computational models based on an egocentric notion of norms. Here, using a combination of model-based fMRI and third party punishment games, we show that brain regions previously implicated in egocentric norm enforcement critically extend to the important case of norm enforcement by unaffected third parties. Specifically, we found that responses in the ACC and insula cortex were positively associated with detection of distributional inequity, while those in the anterior DLPFC were associated with assessment of intentionality to the violator. Moreover, during sanction decisions, the subjective value of sanctions modulated activity in both vmPFC and rTPJ. These results shed light on the neurocomputational underpinnings of third party punishment and evolutionary origin of human norm enforcement. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Toleration and the Design of Norms.

    PubMed

    Floridi, Luciano

    2015-10-01

    One of the pressing challenges we face today-in a post-Westphalian order (emergence of the state as the modern, political information agent) and post-Bretton Woods world (emergence of non-state multiagent systems or MASs as "hyperhistorical" players in the global economy and politics)-is how to design the right kind of MAS that can take full advantage of the socio-economic and political progress made so far, while dealing successfully with the new global challenges that are undermining the best legacy of that very progress. This is the topic of the article. In it, I argue that (i) in order to design the right kind of MAS, we need to design the right kind of norms that constitute them; (ii) in order to design the right kind of constitutive norms, we need to identify and adopt the right kind of principles of normative design; (iii) toleration is one of those principles; (iv) unfortunately, its role as a foundation for the design of norms has been undermined by the "paradox of toleration"; (v) however, the paradox can be solved; (vi) so toleration can be re-instated as the right kind of foundational principle for the design of the right kind of norms that can constitute the right kind of MAS that can operate across cultures, societies and states, to help us to tackle the new global challenges facing us.

  7. Novel roles for LIX1L in promoting cancer cell proliferation through ROS1-mediated LIX1L phosphorylation

    PubMed Central

    Nakamura, Satoki; Kahyo, Tomoaki; Tao, Hong; Shibata, Kiyoshi; Kurabe, Nobuya; Yamada, Hidetaka; Shinmura, Kazuya; Ohnishi, Kazunori; Sugimura, Haruhiko

    2015-01-01

    Herein, we report the characterization of Limb expression 1-like, (LIX1L), a putative RNA-binding protein (RBP) containing a double-stranded RNA binding motif, which is highly expressed in various cancer tissues. Analysis of MALDI-TOF/TOF mass spectrometry and RNA immunoprecipitation-sequencing of interacting proteins and the microRNAs (miRNAs) bound to LIX1L revealed that LIX1L interacts with proteins (RIOK1, nucleolin and PABPC4) and miRNAs (has-miRNA-520a-5p, −300, −216b, −326, −190a, −548b-3p, −7–5p and −1296) in HEK-293 cells. Moreover, the reduction of phosphorylated Tyr136 (pTyr136) in LIX1L through the homeodomain peptide, PY136, inhibited LIX1L-induced cell proliferation in vitro, and PY136 inhibited MKN45 cell proliferation in vivo. We also determined the miRNA-targeted genes and showed that was apoptosis induced through the reduction of pTyr136. Moreover, ROS1, HCK, ABL1, ABL2, JAK3, LCK and TYR03 were identified as candidate kinases responsible for the phosphorylation of Tyr136 of LIX1L. These data provide novel insights into the biological significance of LIX1L, suggesting that this protein might be an RBP, with implications for therapeutic approaches for targeting LIX1L in LIX1L-expressing cancer cells. PMID:26310847

  8. Wired: Energy Drinks, Jock Identity, Masculine Norms, and Risk Taking

    PubMed Central

    Miller, Kathleen E.

    2008-01-01

    Objective The author examined gendered links among sport-related identity, endorsement of conventional masculine norms, risk taking, and energy-drink consumption. Participants The author surveyed 795 undergraduate students enrolled in introductory-level courses at a public university. Methods The author conducted linear regression analyses of energy-drink consumption frequencies on sociodemographic characteristics, jock identity, masculine norms, and risk-taking behavior. Results Of participants, 39% consumed an energy drink in the past month, with more frequent use by men (2.49 d/month) than by women (1.22 d/month). Strength of jock identity was positively associated with frequency of energy-drink consumption; this relationship was mediated by both masculine norms and risk-taking behavior. Conclusions Sport-related identity, masculinity, and risk taking are components of the emerging portrait of a toxic jock identity, which may signal an elevated risk for health-compromising behaviors. College undergraduates’ frequent consumption of Red Bull and comparable energy drinks should be recognized as a potential predictor of toxic jock identity. PMID:18400659

  9. Wired: energy drinks, jock identity, masculine norms, and risk taking.

    PubMed

    Miller, Kathleen E

    2008-01-01

    The author examined gendered links among sport-related identity, endorsement of conventional masculine norms, risk taking, and energy-drink consumption. The author surveyed 795 undergraduate students enrolled in introductory-level courses at a public university. The author conducted linear regression analyses of energy-drink consumption frequencies on sociodemographic characteristics, jock identity, masculine norms, and risk-taking behavior. Of participants, 39% consumed an energy drink in the past month, with more frequent use by men (2.49 d/month) than by women (1.22 d/month). Strength of jock identity was positively associated with frequency of energy-drink consumption; this relationship was mediated by both masculine norms and risk-taking behavior. Sport-related identity, masculinity, and risk taking are components of the emerging portrait of a toxic jock identity, which may signal an elevated risk for health-compromising behaviors. College undergraduates' frequent consumption of Red Bull and comparable energy drinks should be recognized as a potential predictor of toxic jock identity.

  10. L1-CAM in cancerous tissues.

    PubMed

    Gavert, Nancy; Ben-Shmuel, Amir; Raveh, Shani; Ben-Ze'ev, Avri

    2008-11-01

    L1-cell adhesion molecule (L1-CAM) is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brain cells, in recent years L1-CAM has been detected in other tissues, and in a variety of cancer cells, including some common types of human cancer. We review the prevalence of L1-CAM in human cancer, the possible mechanisms involved in L1-CAM-mediated tumorigenesis, and cancer therapies based upon L1-CAM antibody treatment. In colon cancer cells, the L1-CAM gene was identified as a target of the Wnt/beta-catenin-TCF signaling pathway, and L1-CAM was exclusively detected at the invasive front of colon and ovarian cancer tissue. The expression of L1-CAM in normal and cancer cells enhanced tumorigenesis and conferred metastasis in colon cancer cells. Antibodies against the L1-CAM ectodomain severely inhibited the proliferation of a variety of cancer cells in culture and reduced tumor burden when injected into mice harboring cancer cells expressing L1-CAM. These results, in addition to the presence of L1-CAM on the cell surface and its restricted distribution in normal tissues, make it an ideal target for tumor therapy.

  11. Privacy, technology, and norms: the case of Smart Meters.

    PubMed

    Horne, Christine; Darras, Brice; Bean, Elyse; Srivastava, Anurag; Frickel, Scott

    2015-05-01

    Norms shift and emerge in response to technological innovation. One such innovation is Smart Meters - components of Smart Grid energy systems capable of minute-to-minute transmission of consumer electricity use information. We integrate theory from sociological research on social norms and privacy to examine how privacy threats affect the demand for and expectations of norms that emerge in response to new technologies, using Smart Meters as a test case. Results from three vignette experiments suggest that increased threats to privacy created by Smart Meters are likely to provoke strong demand for and expectations of norms opposing the technology and that the strength of these normative rules is at least partly conditional on the context. Privacy concerns vary little with actors' demographic characteristics. These findings contribute to theoretical understanding of norm emergence and have practical implications for implementing privacy protections that effectively address concerns of electricity users. Copyright © 2014 Elsevier Inc. All rights reserved.

  12. Least-squares finite element methods for compressible Euler equations

    NASA Technical Reports Server (NTRS)

    Jiang, Bo-Nan; Carey, G. F.

    1990-01-01

    A method based on backward finite differencing in time and a least-squares finite element scheme for first-order systems of partial differential equations in space is applied to the Euler equations for gas dynamics. The scheme minimizes the L-sq-norm of the residual within each time step. The method naturally generates numerical dissipation proportional to the time step size. An implicit method employing linear elements has been implemented and proves robust. For high-order elements, computed solutions based on the L-sq method may have oscillations for calculations at similar time step sizes. To overcome this difficulty, a scheme which minimizes the weighted H1-norm of the residual is proposed and leads to a successful scheme with high-degree elements. Finally, a conservative least-squares finite element method is also developed. Numerical results for two-dimensional problems are given to demonstrate the shock resolution of the methods and compare different approaches.

  13. Kolkata Paise Restaurant Problem and the Cyclically Fair Norm

    NASA Astrophysics Data System (ADS)

    Banerjee, Priyodorshi; Mitra, Manipushpak; Mukherjee, Conan

    In this paper we revisit the Kolkata Paise Restaurant problem by allowing for a more general (but common) preference of the n customers defined over the set of n restaurants. This generalization allows for the possibility that each pure strategy Nash equilibrium differs from the Pareto efficient allocation. By assuming that n is small and by allowing for mutual interaction across all customers we design strategies to sustain cyclically fair norm as a sub-game perfect equilibrium of the Kolkata Paise Restaurant problem. We have a cyclically fair norm if n strategically different Pareto efficient strategies are sequentially sustained in a way such that each customer gets serviced in all the n restaurants exactly once between periods 1 and n and then again the same process is repeated between periods (n+1) and 2n and so on.

  14. Norm stability at Alcatraz Island: Effects of time and changing conditions

    Treesearch

    William Valliere; Robert Manning

    2010-01-01

    Research suggests that visitors often have norms about the resource and social conditions acceptable in a park and that understanding such norms can be useful for park management. Most studies of norms use data from cross-sectional surveys, and little is known about how norms may change over time. To explore this issue, we conducted a study in 2007 to determine whether...

  15. Tumor cells versus host immune cells: whose PD-L1 contributes to PD-1/PD-L1 blockade mediated cancer immunotherapy?

    PubMed

    Tang, Fei; Zheng, Pan

    2018-01-01

    Antibody blockade of the PD-1/PD-L1 pathway has elicited durable antitumor responses in the therapy of a broad spectrum of cancers. PD-L1 is constitutively expressed in certain tumors and host immune cells, and its expression can be induced or maintained by many factors. The expression of PD-L1 on tumor tissues has been reported to be positively correlated with the efficacy of anti-PD-1/PD-L1 therapy in patients. However, multiple clinical trials indicate that patients with PD-L1-negative tumors also respond to this blockade therapy, which suggests the potential contribution of PD-L1 from host immune cells. Recently, six articles independently evaluated and verified the contributions of PD-L1 from tumor versus non-tumor cells in various mouse tumor models. These studies confirmed that PD-L1 on either tumor cells or host immune cells contributes to tumor escape, and the relative contributions of PD-L1 on these cells seem to be context-dependent. While both tumor- and host-derived PD-L1 can play critical roles in immune suppression, differences in tumor immunogenicity appear to underlie their relative importance. Notably, these reports highlight the essential roles of PD-L1 from host myeloid cells in negatively regulating T cell activation and limiting T cell trafficking. Therefore, comprehensive evaluating the global PD-L1 expression, rather than monitoring PD-L1 expression on tumor cells alone, should be a more accurate way for predicting responses in PD-1/PD-L1 blockade therapy in cancer patients.

  16. A Neural Mechanism of Strategic Social Choice under Sanction-Induced Norm Compliance1,2,3

    PubMed Central

    Makwana, Aidan; Grön, Georg; Fehr, Ernst

    2015-01-01

    Abstract In recent years, much has been learned about the representation of subjective value in simple, nonstrategic choices. However, a large fraction of our daily decisions are embedded in social interactions in which value guided decisions require balancing benefits for self against consequences imposed by others in response to our choices. Yet, despite their ubiquity, much less is known about how value computation takes place in strategic social contexts that include the possibility of retribution for norm violations. Here, we used functional magnetic resonance imaging (fMRI) to show that when human subjects face such a context connectivity increases between the temporoparietal junction (TPJ), implicated in the representation of other peoples’ thoughts and intentions, and regions of ventromedial prefrontal cortex (vmPFC) that are associated with value computation. In contrast, we find no increase in connectivity between these regions in social nonstrategic cases where decision-makers are immune from retributive monetary punishments from a human partner. Moreover, there was also no increase in TPJ-vmPFC connectivity when the potential punishment was performed by a computer programmed to punish fairness norm violations in the same manner as a human would. Thus, TPJ-vmPFC connectivity is not simply a function of the social or norm enforcing nature of the decision, but rather occurs specifically in situations where subjects make decisions in a social context and strategically consider putative consequences imposed by others. PMID:26464981

  17. Predicting negative drinking consequences: examining descriptive norm perception.

    PubMed

    Benton, Stephen L; Downey, Ronald G; Glider, Peggy S; Benton, Sherry A; Shin, Kanghyun; Newton, Douglas W; Arck, William; Price, Amy

    2006-05-01

    This study explored how much variance in college student negative drinking consequences is explained by descriptive norm perception, beyond that accounted for by student gender and self-reported alcohol use. A derivation sample (N=7565; 54% women) and a replication sample (N=8924; 55.5% women) of undergraduate students completed the Campus Alcohol Survey in classroom settings. Hierarchical regression analyses revealed that student gender and average number of drinks when "partying" were significantly related to harmful consequences resulting from drinking. Men reported more consequences than did women, and drinking amounts were positively correlated with consequences. However, descriptive norm perception did not explain any additional variance beyond that attributed to gender and alcohol use. Furthermore, there was no significant three-way interaction among student gender, alcohol use, and descriptive norm perception. Norm perception contributed no significant variance in explaining harmful consequences beyond that explained by college student gender and alcohol use.

  18. Predicting Drinking Behavior and Alcohol-Related Problems Among Fraternity and Sorority Members: Examining the Role of Descriptive and Injunctive Norms

    PubMed Central

    Larimer, Mary E.; Turner, Aaron P.; Mallett, Kimberly A.; Geisner, Irene Markman

    2010-01-01

    The authors examined the relation between Greek students’ perceptions of alcohol consumption in their pledge classes (descriptive norms) and acceptability of drinking (injunctive norms) and the ability of these normative influences to predict drinking behavior, alcohol-related negative consequences, and symptoms of alcohol dependence concurrently and prospectively over 1 year. Participants were 279 men and 303 women recruited from incoming pledge classes of 12 fraternities and 6 sororities, who completed measures of descriptive and injunctive norms, alcohol use, and consequences. Results revealed that descriptive norms significantly predicted concurrent drinking. After controlling for baseline drinking, injunctive norms significantly predicted drinking 1 year later and predicted alcohol-related consequences and dependency symptoms at baseline and follow-up. The potential to incorporate injunctive norms into preventive interventions is discussed. PMID:15482075

  19. Development, social norms, and assignment to task

    PubMed Central

    Fafchamps, Marcel

    2011-01-01

    Economic development involves a structural transformation in the way people are allocated to tasks. There is a shift from self-provision to market exchange, facilitating specialization. There is also a shift from self-employment to wage employment in large firms and organizations, driven by innovation and increasing returns to scale. Changes in allocation mechanisms require changes in norms and attitudes. Because different labor assignment domains coexist, conflicts arise among norms that apply to different domains, possibly resulting in dysfunctional outcomes. I argue that religion, humanism, and schools have all played an important historical role in fostering the changes in social norms and attitudes that are needed to accompany structural changes in the way economies allocate workers to tasks. PMID:22198757

  20. Diversity-induced resonance in the response to social norms

    NASA Astrophysics Data System (ADS)

    Tessone, Claudio J.; Sánchez, Angel; Schweitzer, Frank

    2013-02-01

    In this paper we focus on diversity-induced resonance, which was recently found in bistable, excitable, and other physical systems. We study the appearance of this phenomenon in a purely economic model of cooperating and defecting agents. An agent's contribution to a public good is seen as a social norm, so defecting agents face a social pressure, which decreases if free riding becomes widespread. In this model, diversity among agents naturally appears because of the different sensitivities towards the social norm. We study the evolution of cooperation as a response to the social norm (i) for the replicator dynamics and (ii) for the logit dynamics by means of numerical simulations. Diversity-induced resonance is observed as a maximum in the response of agents to changes in the social norm as a function of the degree of heterogeneity in the population. We provide an analytical, mean-field approach for the logit dynamics and find very good agreement with the simulations. From a socioeconomic perspective, our results show that, counterintuitively, diversity in the individual sensitivity to social norms may result in a society that better follows such norms as a whole, even if part of the population is less prone to follow them.

  1. On the Normed Space of Equivalence Classes of Fuzzy Numbers

    PubMed Central

    Lu, Chongxia; Zhang, Wei

    2013-01-01

    We study the norm induced by the supremum metric on the space of fuzzy numbers. And then we propose a method for constructing a norm on the quotient space of fuzzy numbers. This norm is very natural and works well with the induced metric on the quotient space. PMID:24072984

  2. Computational substrates of norms and their violations during social exchange.

    PubMed

    Xiang, Ting; Lohrenz, Terry; Montague, P Read

    2013-01-16

    Social norms in humans constrain individual behaviors to establish shared expectations within a social group. Previous work has probed social norm violations and the feelings that such violations engender; however, a computational rendering of the underlying neural and emotional responses has been lacking. We probed norm violations using a two-party, repeated fairness game (ultimatum game) where proposers offer a split of a monetary resource to a responder who either accepts or rejects the offer. Using a norm-training paradigm where subject groups are preadapted to either high or low offers, we demonstrate that unpredictable shifts in expected offers creates a difference in rejection rates exhibited by the two responder groups for otherwise identical offers. We constructed an ideal observer model that identified neural correlates of norm prediction errors in the ventral striatum and anterior insula, regions that also showed strong responses to variance-prediction errors generated by the same model. Subjective feelings about offers correlated with these norm prediction errors, and the two signals displayed overlapping, but not identical, neural correlates in striatum, insula, and medial orbitofrontal cortex. These results provide evidence for the hypothesis that responses in anterior insula can encode information about social norm violations that correlate with changes in overt behavior (changes in rejection rates). Together, these results demonstrate that the brain regions involved in reward prediction and risk prediction are also recruited in signaling social norm violations.

  3. Computational Substrates of Norms and Their Violations during Social Exchange

    PubMed Central

    Xiang, Ting; Lohrenz, Terry; Montague, P. Read

    2013-01-01

    Social norms in humans constrain individual behaviors to establish shared expectations within a social group. Previous work has probed social norm violations and the feelings that such violations engender; however, a computational rendering of the underlying neural and emotional responses has been lacking. We probed norm violations using a two-party, repeated fairness game (ultimatum game) where proposers offer a split of a monetary resource to a responder who either accepts or rejects the offer. Using a norm-training paradigm where subject groups are preadapted to either high or low offers, we demonstrate that unpredictable shifts in expected offers creates a difference in rejection rates exhibited by the two responder groups for otherwise identical offers. We constructed an ideal observer model that identified neural correlates of norm prediction errors in the ventral striatum and anterior insula, regions that also showed strong responses to variance-prediction errors generated by the same model. Subjective feelings about offers correlated with these norm prediction errors, and the two signals displayed overlapping, but not identical, neural correlates in striatum, insula, and medial orbitofrontal cortex. These results provide evidence for the hypothesis that responses in anterior insula can encode information about social norm violations that correlate with changes in overt behavior (changes in rejection rates). Together, these results demonstrate that the brain regions involved in reward prediction and risk prediction are also recruited in signaling social norm violations. PMID:23325247

  4. Masculinity and HIV: Dimensions of masculine norms that contribute to men’s HIV-related sexual behaviors

    PubMed Central

    Fleming, Paul J.; DiClemente, Ralph J.; Barrington, Clare

    2016-01-01

    Numerous studies have documented a relationship between masculine norms and men’s HIV-related sexual behaviors, but intervening upon this relationship requires a nuanced understanding of the specific aspects of masculine norms that shape men’s sexual behaviors. We integrate theories on masculinities with empirical HIV research to identify specific dimensions of masculine norms that influence men’s HIV-related sexual behaviors. We identify three major dimensions of masculine norms that shape men’s sexual behavior: 1) uncontrollable male sex drive, 2) capacity to perform sexually, and 3) power over others. While the existing literature does help explain the relationship between masculine norms and men’s sexual behaviors several gaps remain including: a recognition of context-specific masculinities, an interrogation of the positive influences of masculinity, adoption of an intersectional approach, assessment of changes in norms and behaviors over time, and rigorous evaluations of gender-transformative approaches. Addressing these gaps in future research may optimize prevention efforts. PMID:26696261

  5. Predicting condom use attitudes, norms, and control beliefs in Hispanic problem behavior youth: the effects of family functioning and parent-adolescent communication about sex on condom use.

    PubMed

    Malcolm, Shandey; Huang, Shi; Cordova, David; Freitas, Derek; Arzon, Margaret; Jimenez, Giselle Leon; Pantin, Hilda; Prado, Guillermo

    2013-08-01

    Hispanic problem behavior youth are at an increased risk of engaging in HIV risk behaviors, including low condom use. However, relatively little research has examined factors that affect condom use in this population. Although research indicates that family processes, such as higher levels of family functioning and open parent-adolescent communication about sex, and condom use attitudes, norms, and control beliefs as depicted by the theory of planned behavior have an effect on condom use behaviors, the combination of the two factors has received minimal attention. The purpose of this study was to examine the effect of family functioning on condom use intentions and behaviors through communication about sex and condom use attitudes, parental norms, and control beliefs. A cross-sectional study of 171 predominately male (73.1%) sexually active Hispanic problem behavior adolescents (mean age = 14.88 years) was conducted. Structural equation modeling was used to test the study hypothesis. Findings largely support the overall model and suggest that family functioning had an indirect effect on condom use intention and behavior through communication about sex, condom use attitudes, and control beliefs. Family functioning, however, did not have an indirect effect on condom use intention and behavior through communication about sex and parental norms. Implications for prevention science and future research are discussed.

  6. Clinical ethics and values: how do norms evolve from practice?

    PubMed

    Spranzi, Marta

    2013-02-01

    Bioethics laws in France have just undergone a revision process. The bioethics debate is often cast in terms of ethical principles and norms resisting emerging social and technological practices. This leads to the expression of confrontational attitudes based on widely differing interpretations of the same principles and values, and ultimately results in a deadlock. In this paper I would like to argue that focusing on values, as opposed to norms and principles, provides an interesting perspective on the evolution of norms. As Joseph Raz has convincingly argued, "life-building" values and practices are closely intertwined. Precisely because values have a more indeterminate meaning than norms, they can be cited as reasons for action by concerned stakeholders, and thus can help us understand how controversial practices, e.g. surrogate motherhood, can be justified. Finally, norms evolve when the interpretations of the relevant values shift and cause a change in the presumptions implicit in the norms. Thus, norms are not a prerequisite of the ethical solution of practical dilemmas, but rather the outcome of the decision-making process itself. Struggling to reach the right decision in controversial clinical ethics situations indirectly causes social and moral values to change and principles to be understood differently.

  7. Clarifying the contribution of subjective norm to predicting leisure-time exercise.

    PubMed

    Okun, Morris A; Karoly, Paul; Lutz, Rafer

    2002-01-01

    To clarify the contribution of subjective norm to exercise intention and behavior by considering the influence of descriptive as well as injunctive social norms related to family and friends. A sample of 530 college students completed a questionnaire that assessed descriptive and injunctive social norms related to family and to friends, perceived behavioral control, attitude, intention, and leisure-time exercise. Friend descriptive social norm was a significant predictor of both intention (p<.05) and leisure-time exercise (p<.001). Descriptive norms should be incorporated into tests of the theory of planned behavior in the exercise domain.

  8. The Role of Values, Moral Norms, and Descriptive Norms in Building Occupant Responses to an Energy-Efficiency Pilot Program and to Framing of Related Messages

    ERIC Educational Resources Information Center

    Arpan, Laura M.; Barooah, Prabir; Subramany, Rahul

    2015-01-01

    This study examined building occupants' responses associated with an occupant-based energy-efficiency pilot in a university building. The influence of occupants' values and norms as well as effects of two educational message frames (descriptive vs. moral norms cues) on program support were tested. Occupants' personal moral norm to conserve energy…

  9. Understanding the MBA Gender Gap: Women Respond to Gender Norms by Reducing Public Assertiveness but Not Private Effort.

    PubMed

    Wallen, Aaron S; Morris, Michael W; Devine, Beth A; Lu, Jackson G

    2017-08-01

    Women's underperformance in MBA programs has been the subject of recent debate and policy interventions, despite a lack of rigorous evidence documenting when and why it occurs. The current studies document a performance gap, specifying its contours and contributing factors. Two behaviors by female students that may factor into the gap are public conformity and private internalization. We predicted that women conform to the norm associating maleness with technical prowess by minimizing their public assertiveness in class discussions and meetings, but that they do not internalize the norm by reducing private effort. Data from multiple cohorts of a top-ranked MBA program reveal female underperformance occurred in technical subjects (e.g., accounting), but not social subjects (e.g., marketing). As predicted, the gender effect ran not through private effort but through public assertiveness, even controlling for gender differences in interests and aptitudes. These findings support some current policy interventions while casting doubt on others.

  10. Reciprocal relationships over time between descriptive norms and alcohol use in young adult sexual minority women.

    PubMed

    Litt, Dana M; Lewis, Melissa A; Rhew, Isaac C; Hodge, Kimberley A; Kaysen, Debra L

    2015-12-01

    Young adulthood, roughly ages 18-25, is a period of great risk for excessive consumption of alcohol, especially among sexual minority women (SMW). Despite the substantial literature examining the relationships between social norms and behavior in general, little attention has been given to the role of descriptive norms on the drinking behaviors of sexual minorities. The present study had 3 aims: to compare both typical woman descriptive norms and sexual minority-specific descriptive normative perceptions among a sample of SMW, to examine reciprocal associations between sexual minority-specific descriptive norms and alcohol consumption over time, and to examine whether these reciprocal associations were moderated by sexual orientation (i.e., whether 1 identifies as lesbian or bisexual). A national sample of 1,057 lesbian and bisexual women between the ages of 18 and 25 was enrolled in this study. Participants completed an online survey at 4 time points that assessed the constructs of interest. Results indicated that SMW consistently perceived that SMW drank more than their nonsexual minority peers; that SMW-specific descriptive drinking norms and alcohol consumption influenced 1 another over time in a reciprocal, feed-forward fashion; and that these associations were not moderated by sexual orientation. These findings highlight the importance of considering SMW-specific norms as an important factor in predicting alcohol consumption in SMW. Results further support the development and testing of normative interventions for high-risk drinking among SMW. (c) 2016 APA, all rights reserved).

  11. Cyber Norms for Civilian Nuclear Power Plants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Spirito, Christopher

    The international community agrees that the safe operation of civilian nuclear infrastructure is in every population’s best interest. One challenge each government must address is defining and agreeing to a set of acceptable norms of behavior in cyberspace as they relate to these facilities. The introduction of digital systems and networking technologies into these environments has led to the possibility that control and supporting computer systems are now accessible and exploitable, especially where interconnections to global information and communications technology (ICT) networks exist. The need for norms of behavior in cyberspace includes what is expected of system architects and cybermore » defenders as well as adversaries who should abide by rules of engagement even while conducting acts that violate national and international laws. The goal of this paper is to offer three behavioral cyber norms to improve the overall security of the ICT and Operational Technology (OT) networks and systems that underlie the operations of nuclear facilities. These norms of behavior will be specifically defined with the goals of reducing the threats associated to the theft of nuclear materials, accidental release of radiation and sabotage of nuclear processes. These norms would also include instances where an unwitting attacker or intelligence collection entity inadvertently makes their way into a nuclear facility network or system and can recognize they are in a protected zone and an approach to ensuring that these zones are not exploitable by bad actors to place their sensitive cyber effect delivery systems.« less

  12. Effectiveness of anti-PD-1/PD-L1 antibodies in urothelial carcinoma patients with different PD-L1 expression levels: a meta-analysis.

    PubMed

    Liu, Junqi; Zhang, Chuanfeng; Hu, Jiegang; Tian, Qing; Wang, Xin; Gu, Hao; Zhang, Song; Zhao, Di; Fan, Ruitai

    2018-02-23

    Urothelial carcinoma ranks the ninth among malignant cancers. We conducted this study to identify which patients could benefit more from the treatment of programmed death-1 (PD-1)/programmed death-ligand1 (PD-L1) inhibitors. We performed literature searches, combined data from qualified literature and performed comparative analyses on the effectiveness of anti-PD-1/PD-L1 antibodies in patients with different PD-L1 expression levels. We divided patients into three groups according to the percentages of PD-L1-positive cells, namely the low- PD-L1 (PD-L1 < 1%), the medium-PD-L1 (PD-L11 and < 5%) and the high-PD-L1 (PD-L1 ≥ 5%) groups. We found that the high-PD-L1 group responded significantly better than other groups (P = 0.0003, ORs = 0.45, 95%CI: 0.29-071; P = 0.0009, ORs = 0.43, 95%CI: 0.25-0.73, for low-PD-L1 and medium-PD-L1 groups, respectively), while the latter two groups responded similarly (P = 0.90, ORs = 1.06, 95%CI: 0.62-1.83) to both PD-1 and PD-L1 inhibitors. Furthermore, we found that the medium-PD-L1 and high-PD-L1 groups responded similarly to PD-1/ PD-L1 inhibitors (P = 0.65, ORs = 1.11, 95%CI: 0.69-1.77), while the low-PD-L1 group responded better to PD-1 inhibitors than PD-L1 inhibitors (P = 0.046, ORs = 1.92, 95%CI: 0.98-3.89). Our results suggest that PD-L1 positive patients should be defined as those with ≥ 5% or greaterPD-L1-positive cells. PD-1 antibodies performed better only in the low-group patients, likely because they could block the interactions of PD-1 with both PD-L1 and PD-L2.

  13. The Maturation of Norms for Computer-Mediated Communication.

    ERIC Educational Resources Information Center

    Newby, Gregory B.

    1993-01-01

    Analyzes the communication norms of the major forms of computer-mediated communication, including electronic mail, mailing lists, Usenet and other bulletin board systems, interactive messaging, multiuser domains (MUDs), and mass-broadcast media. New uses and the development of standards, or norms, are discussed. (Contains 11 references.) (LRW)

  14. $L^1$ penalization of volumetric dose objectives in optimal control of PDEs

    DOE PAGES

    Barnard, Richard C.; Clason, Christian

    2017-02-11

    This work is concerned with a class of PDE-constrained optimization problems that are motivated by an application in radiotherapy treatment planning. Here the primary design objective is to minimize the volume where a functional of the state violates a prescribed level, but prescribing these levels in the form of pointwise state constraints leads to infeasible problems. We therefore propose an alternative approach based on L 1 penalization of the violation that is also applicable when state constraints are infeasible. We establish well-posedness of the corresponding optimal control problem, derive first-order optimality conditions, discuss convergence of minimizers as the penalty parametermore » tends to infinity, and present a semismooth Newton method for their efficient numerical solution. Finally, the performance of this method for a model problem is illustrated and contrasted with an alternative approach based on (regularized) state constraints.« less

  15. English semantic word-pair norms and a searchable Web portal for experimental stimulus creation.

    PubMed

    Buchanan, Erin M; Holmes, Jessica L; Teasley, Marilee L; Hutchison, Keith A

    2013-09-01

    As researchers explore the complexity of memory and language hierarchies, the need to expand normed stimulus databases is growing. Therefore, we present 1,808 words, paired with their features and concept-concept information, that were collected using previously established norming methods (McRae, Cree, Seidenberg, & McNorgan Behavior Research Methods 37:547-559, 2005). This database supplements existing stimuli and complements the Semantic Priming Project (Hutchison, Balota, Cortese, Neely, Niemeyer, Bengson, & Cohen-Shikora 2010). The data set includes many types of words (including nouns, verbs, adjectives, etc.), expanding on previous collections of nouns and verbs (Vinson & Vigliocco Journal of Neurolinguistics 15:317-351, 2008). We describe the relation between our and other semantic norms, as well as giving a short review of word-pair norms. The stimuli are provided in conjunction with a searchable Web portal that allows researchers to create a set of experimental stimuli without prior programming knowledge. When researchers use this new database in tandem with previous norming efforts, precise stimuli sets can be created for future research endeavors.

  16. Ways of giving benefits in marriage: norm use, relationship satisfaction, and attachment-related variability.

    PubMed

    Clark, Margaret S; Lemay, Edward P; Graham, Steven M; Pataki, Sherri P; Finkel, Eli J

    2010-07-01

    Couples reported on bases for giving support and on relationship satisfaction just prior to and approximately 2 years into marriage. Overall, a need-based, noncontingent (communal) norm was seen as ideal and was followed, and greater use of this norm was linked to higher relationship satisfaction. An exchange norm was seen as not ideal and was followed significantly less frequently than was a communal norm; by 2 years into marriage, greater use of an exchange norm was linked with lower satisfaction. Insecure attachment predicted greater adherence to an exchange norm. Idealization of and adherence to a communal norm dropped slightly across time. As idealization of a communal norm and own use and partner use of a communal norm decreased, people high in avoidance increased their use of an exchange norm, whereas people low in avoidance decreased their use of an exchange norm. Anxious individuals evidenced tighter links between norm use and marital satisfaction relative to nonanxious individuals. Overall, a picture of people valuing a communal norm and striving toward adherence to a communal norm emerged, with secure individuals doing so with more success and equanimity across time than insecure individuals.

  17. L1 French Learning of L2 Spanish Past Tenses: L1 Transfer versus Aspect and Interface Issues

    ERIC Educational Resources Information Center

    Amenós-Pons, José; Ahern, Aoife; Gujarro-Fuentes, Pedro

    2017-01-01

    This paper examines the process of acquiring L2s that are closely related to the L1 through data on how adult French speakers learning L2 Spanish in a formal setting develop knowledge and use of past tenses in this L2. We consider the role of transfer and simplification in acquiring mental representations of the L2 grammar, specifically in the…

  18. Investigating Shared Norms in Multicultural Teams: Exploring How Team Member Scripts and Cognitive Adjustment Strategies Impact the Norm Formation Process

    ERIC Educational Resources Information Center

    McGurrin, Daniel Paul

    2015-01-01

    The purpose of this study was to understand how shared norms are developed in the early phase of multicultural team (MCT) formation. The development of shared norms is recognized as critical to MCTs' contributions to organizations, and they are a result of the cognitive adjustment of the team members in recognition of their differences (Brandl…

  19. Low gamma counting for measuring NORM/TENORM with a radon reducing system

    NASA Astrophysics Data System (ADS)

    Paschoa, Anselmo S.

    2001-06-01

    A detection system for counting low levels of gamma radiation was built by upgrading an existing rectangular chamber made of 18 metric tonne of steel fabricated before World War II. The internal walls, the ceiling, and the floor of the chamber are covered with copper sheets. The new detection system consists of a stainless steel hollow cylinder with variable circular apertures in the cylindrical wall and in the base, to allow introduction of a NaI (Tl) crystal, or alternatively, a HPGe detector in its interior. This counting system is mounted inside the larger chamber, which in turn is located in a subsurface air-conditioned room. The access to the subsurface room is made from a larger entrance room through a tunnel plus a glass anteroom to decrease the air-exchange rate. Both sample and detector are housed inside the stainless steel cylinder. This cylinder is filled with hyper pure nitrogen gas, before counting a sample, to prevent radon coming into contact with the detector surface. As a consequence, the contribution of the 214Bi photopeaks to the background gamma spectra is minimized. The reduction of the gamma radiation background near the detector facilitates measurement of naturally occurring radioactive materials (NORM), and/or technologically enhanced NORM (TENORM), which are usually at concentration levels only slightly higher than those typically found in the natural radioactive background.

  20. Minimal models from W-constrained hierarchies via the Kontsevich-Miwa transform

    NASA Astrophysics Data System (ADS)

    Gato-Rivera, B.; Semikhatov, A. M.

    1992-08-01

    A direct relation between the conformal formalism for 2D quantum gravity and the W-constrained KP hierarchy is found, without the need to invoke intermediate matrix model technology. The Kontsevich-Miwa transform of the KP hierarchy is used to establish an identification between W constraints on the KP tau function and decoupling equations corresponding to Virasoro null vectors. The Kontsevich-Miwa transform maps the W ( l) -constrained KP hierarchy to the ( p‧, p‧) minimal model, with the tau function being given by the correlator of a product of (dressed) ( l, 1) [or (1, l)] operators, provided the Miwa parameter ni and the free parameter (an abstract bc spin) present in the constraint are expressed through the ratio p‧/ p and the level l.

  1. Predictive Hyperglycemia and Hypoglycemia Minimization: In-Home Evaluation of Safety, Feasibility, and Efficacy in Overnight Glucose Control in Type 1 Diabetes.

    PubMed

    Spaic, Tamara; Driscoll, Marsha; Raghinaru, Dan; Buckingham, Bruce A; Wilson, Darrell M; Clinton, Paula; Chase, H Peter; Maahs, David M; Forlenza, Gregory P; Jost, Emily; Hramiak, Irene; Paul, Terri; Bequette, B Wayne; Cameron, Faye; Beck, Roy W; Kollman, Craig; Lum, John W; Ly, Trang T

    2017-03-01

    The objective of this study was to determine the safety, feasibility, and efficacy of a predictive hyperglycemia and hypoglycemia minimization (PHHM) system compared with predictive low-glucose insulin suspension (PLGS) alone in overnight glucose control. A 42-night trial was conducted in 30 individuals with type 1 diabetes in the age range 15-45 years. Participants were randomly assigned each night to either PHHM or PLGS and were blinded to the assignment. The system suspended the insulin pump on both the PHHM and PLGS nights for predicted hypoglycemia but delivered correction boluses for predicted hyperglycemia on PHHM nights only. The primary outcome was the percentage of time spent in a sensor glucose range of 70-180 mg/dL during the overnight period. The addition of automated insulin delivery with PHHM increased the time spent in the target range (70-180 mg/dL) from 71 ± 10% during PLGS nights to 78 ± 10% during PHHM nights ( P < 0.001). The average morning blood glucose concentration improved from 163 ± 23 mg/dL after PLGS nights to 142 ± 18 mg/dL after PHHM nights ( P < 0.001). Various sensor-measured hypoglycemic outcomes were similar on PLGS and PHHM nights. All participants completed 42 nights with no episodes of severe hypoglycemia, diabetic ketoacidosis, or other study- or device-related adverse events. The addition of a predictive hyperglycemia minimization component to our existing PLGS system was shown to be safe, feasible, and effective in overnight glucose control. © 2017 by the American Diabetes Association.

  2. COMPARED TO WHAT? EARLY BRAIN OVERGROWTH IN AUTISM AND THE PERILS OF POPULATION NORMS

    PubMed Central

    Raznahan, Armin; Wallace, Gregory L; Antezana, Ligia; Greenstein, Dede; Lenroot, Rhoshel; Thurm, Audrey; Gozzi, Marta; Spence, Sarah; Martin, Alex; Swedo, Susan E; Giedd, Jay N

    2013-01-01

    Background Early brain overgrowth (EBO) in autism spectrum disorder (ASD) is amongst the best-replicated biological associations in psychiatry. Most positive reports have compared head circumference (HC) in ASD (an excellent proxy for early brain size) with well-known reference norms. We sought to reappraise evidence for the EBO hypothesis given (i) the recent proliferation of longitudinal HC studies in ASD, and (ii) emerging reports that several of the reference norms used to define EBO in ASD may be biased towards detecting HC overgrowth in contemporary samples of healthy children. Methods (1)Systematic review of all published HC studies in children with ASD. (2)Comparison of 330 longitudinally gathered HC measures between birth and 18 months from male children with autism(n=35) and typically developing controls(n=22). Results In systematic review, comparisons with locally recruited controls were significantly less likely to identify EBO in ASD than norm-based studies(p<0.006). Through systematic review and analysis of new data we replicate seminal reports of EBO in ASD relative to classical HC norms, but show that this overgrowth relative to norms is mimicked by patterns of HC growth age in a large contemporary community-based sample of US children(n~75,000). Controlling for known HC norm biases leaves inconsistent support for a subtle, later-emerging and sub-group specific pattern of EBO in clinically-ascertained ASD vs. community controls. Conclusions The best-replicated aspects of EBO reflect generalizable HC norm biases rather than disease-specific biomarkers. The potential HC norm biases we detail are not specific to ASD research, but apply throughout clinical and academic medicine. PMID:23706681

  3. Minimally Invasive Transtubular Endoscopic Decompression for L5 Radiculopathy Induced by Lumbosacral Extraforaminal Lesions

    PubMed Central

    Kitamura, Takahiro; Masuda, Keigo; Hotta, Kensuke; Senba, Hideyuki; Shidahara, Satoshi

    2018-01-01

    Study Design Retrospective study. Purpose This study aimed to evaluate the efficacy of minimally invasive transtubular endoscopic decompression for the treatment of lumbosacral extraforaminal lesion (LSEFL). Overview of Literature Conventional procedures for surgical decompression for the treatment of LSEFL involve certain technical challenges because the lumbosacral extraforaminal region has unique anatomical features. Moreover, the efficacy of minimally invasive procedures performed via the posterolateral approach for LSEFL has been reported. Methods Twenty-five patients who had undergone minimally invasive transtubular endoscopic decompression for the treatment of LSEFL and could be followed up for at least 1 year postoperatively were enrolled. Five of these patients had a history of lumbar surgery, and seven had concomitant adjacent-level spinal stenosis. The clinical outcomes were evaluated using the Japanese Orthopaedic Association (JOA) lumbar score, numeric rating scale (NRS), and the JOA Back Pain Evaluation Questionnaire (JOABPEQ). The mean postoperative follow-up (FU) duration was 3.8 years. Results All procedures could be completed without any severe surgical complications, and all patients could resume their previous activity level within 1 month postoperatively. The JOA score significantly increased from 14.1±4.0 at baseline to 23.1±3.7 at the 1-year FU and 22.1±3.8 at the last FU. Similarly, there were significant improvements in the postoperative NRS and JOABPEQ scores. An additional surgery was performed in two patients (8%) during the FU period. Patients with degenerative scoliosis exhibited significantly poorer outcomes compared with those without this condition. Conclusions Transtubular endoscopic decompression can overcome certain technical challenges involved in the conventional procedures for LSEFL treatment; therefore, it can be recommended as a useful procedure for treating LSEFL. This procedure can provide some benefits to LSEFL

  4. Thematic relatedness production norms for 100 object concepts.

    PubMed

    Jouravlev, Olessia; McRae, Ken

    2016-12-01

    Knowledge of thematic relations is an area of increased interest in semantic memory research because it is crucial to many cognitive processes. One methodological issue that researchers face is how to identify pairs of thematically related concepts that are well-established in semantic memory for most people. In this article, we review existing methods of assessing thematic relatedness and provide thematic relatedness production norming data for 100 object concepts. In addition, 1,174 related concept pairs obtained from the production norms were classified as reflecting one of the five subtypes of relations: attributive, argument, coordinate, locative, and temporal. The database and methodology will be useful for researchers interested in the effects of thematic knowledge on language processing, analogical reasoning, similarity judgments, and memory. These data will also benefit researchers interested in investigating potential processing differences among the five types of semantic relations.

  5. High-affinity PD-1 molecules deliver improved interaction with PD-L1 and PD-L2.

    PubMed

    Li, Yanyan; Liang, Zhaoduan; Tian, Ye; Cai, Wenxuan; Weng, Zhiming; Chen, Lin; Zhang, Huanling; Bao, Yifeng; Zheng, Hongjun; Zeng, Sihai; Bei, Chunhua; Li, Yi

    2018-06-11

    The inhibitory checkpoint molecule programmed death (PD)-1 plays a vital role in maintaining immune homeostasis upon binding to its ligands, PD-L1 and PD-L2. Several recent studies have demonstrated that soluble PD-1 (sPD-1) can block the interaction between membrane PD-1 and PD-L1 to enhance the anti-tumor capability of T cells. However, the affinity of natural sPD-1 binding to PD-L1 is too low to permit therapeutic applications. Here a PD-1 variant with ~3,000-fold and ~70-fold affinity increase to bind PD-L1 and PD-L2, respectively, was generated through directed molecular evolution and phage display technology. Structural analysis showed that mutations at amino acid positions 124 and 132 of PD-1 played major roles in enhancing the affinity of PD-1 binding to its ligands. The high-affinity PD-1 mutant could compete with the binding of antibodies specific to PD-L1 or PD-L2 on cancer cells or dendritic cells (DCs), and it could enhance the proliferation and IFN-γ release of activated lymphocytes. These features potentially qualify the high-affinity PD-1 variant as a unique candidate for the development of a new class of PD-1 immune checkpoint blockade therapeutics. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  6. Predictors of photo naming: Dutch norms for 327 photos.

    PubMed

    Shao, Zeshu; Stiegert, Julia

    2016-06-01

    In the present study, we report naming latencies and norms for 327 photos of objects in Dutch. We provide norms for eight psycholinguistic variables: age of acquisition, familiarity, imageability, image agreement, objective and subjective visual complexity, word frequency, word length in syllables and letters, and name agreement. Furthermore, multiple regression analyses revealed that the significant predictors of photo-naming latencies were name agreement, word frequency, imageability, and image agreement. The naming latencies, norms, and stimuli are provided as supplemental materials.

  7. Swedish women's perceptions of and conformity to feminine norms.

    PubMed

    Kling, Johanna; Holmqvist Gattario, Kristina; Frisén, Ann

    2017-06-01

    The relatively high gender equality in the Swedish society is likely to exert an influence on gender role construction. Hence, the present research aimed to investigate Swedish women's perceptions of and conformity to feminine norms. A mixed methods approach with two studies was used. In Study 1, young Swedish women's gender role conformity, as measured by the Conformity to Feminine Norms Inventory 45 (CFNI-45), was compared to the results from previously published studies in Canada, the United States, and Slovakia. Overall, Swedish women displayed less conformity than their foreign counterparts, with the largest difference on the subscale Sexual fidelity. In Study 2, focus group interviews with young Swedish women added a more complex picture of feminine norms in the Swedish society. For instance the results indicated that Swedish women, while living in a society with a strong gender equality discourse, are torn between the perceived need to invest in their appearances and the risk of being viewed as non-equal when doing so. In sum, despite the fact that traditional gender roles are less pronounced in Sweden, gender role conformity is still a pressing issue. Since attending to the potential roles of feminine norms in women's lives previously has been proposed to be useful in counseling and therapeutic work, the present research also offers valuable information for both researchers and practitioners. [Correction added on 5 May 2017, after first online publication in April 2017: An incorrect Abstract was inadvertently captured in the published article and has been corrected in this current version.]. © 2017 Scandinavian Psychological Associations and John Wiley & Sons Ltd.

  8. Utility of Inferential Norming with Smaller Sample Sizes

    ERIC Educational Resources Information Center

    Zhu, Jianjun; Chen, Hsin-Yi

    2011-01-01

    We examined the utility of inferential norming using small samples drawn from the larger "Wechsler Intelligence Scales for Children-Fourth Edition" (WISC-IV) standardization data set. The quality of the norms was estimated with multiple indexes such as polynomial curve fit, percentage of cases receiving the same score, average absolute…

  9. An integrated moral obligation model for landowner conservation norms

    USGS Publications Warehouse

    Pradhananga, Amit K.; Davenport, Mae A.; Fulton, David C.; Maruyama, Geoffrey M.; Current, Dean

    2017-01-01

    This study applies an integrated moral obligation model to examine the role of environmental and cultural values, and beliefs in the activation of landowner conservation norms. Data for this study were collected through a self-administered survey of riparian landowners in two Minnesota watersheds: Sand Creek and Vermillion River watersheds. Study findings suggest that collectivistic and biospheric–altruistic values form the bases for the activation of personal norms. Further, beliefs about local responsibility and ability to act influence personal norms to protect water resources. Findings suggest that landowners’ personal norms of water conservation are more likely to be activated by conservation strategies that appeal to biospheric–altruistic and collectivistic values, emphasize adverse consequences of water pollution, highlight water resource protection as a local responsibility, and provide the resources needed to protect water resources.

  10. L1 Korean and L1 Mandarin L2 English Learners' Acquisition of the Count/Mass Distinction in English

    ERIC Educational Resources Information Center

    Choi, Sea Hee; Ionin, Tania; Zhu, Yeqiu

    2018-01-01

    This study investigates the second language (L2) acquisition of the English count/mass distinction by speakers of Korean and Mandarin Chinese, with a focus on the semantics of atomicity. It is hypothesized that L1-Korean and L1-Mandarin L2-English learners are influenced by atomicity in the use of the count/mass morphosyntax in English. This…

  11. Local descriptive body weight and dietary norms, food availability, and 10-year change in glycosylated haemoglobin in an Australian population-based biomedical cohort.

    PubMed

    Carroll, Suzanne J; Paquet, Catherine; Howard, Natasha J; Coffee, Neil T; Adams, Robert J; Taylor, Anne W; Niyonsenga, Theo; Daniel, Mark

    2017-02-02

    Individual-level health outcomes are shaped by environmental risk conditions. Norms figure prominently in socio-behavioural theories yet spatial variations in health-related norms have rarely been investigated as environmental risk conditions. This study assessed: 1) the contributions of local descriptive norms for overweight/obesity and dietary behaviour to 10-year change in glycosylated haemoglobin (HbA 1c ), accounting for food resource availability; and 2) whether associations between local descriptive norms and HbA 1c were moderated by food resource availability. HbA 1c , representing cardiometabolic risk, was measured three times over 10 years for a population-based biomedical cohort of adults in Adelaide, South Australia. Residential environmental exposures were defined using 1600 m participant-centred road-network buffers. Local descriptive norms for overweight/obesity and insufficient fruit intake (proportion of residents with BMI ≥ 25 kg/m 2 [n = 1890] or fruit intake of <2 serves/day [n = 1945], respectively) were aggregated from responses to a separate geocoded population survey. Fast-food and healthful food resource availability (counts) were extracted from a retail database. Separate sets of multilevel models included different predictors, one local descriptive norm and either fast-food or healthful food resource availability, with area-level education and individual-level covariates (age, sex, employment status, education, marital status, and smoking status). Interactions between local descriptive norms and food resource availability were tested. HbA 1c concentration rose over time. Local descriptive norms for overweight/obesity and insufficient fruit intake predicted greater rates of increase in HbA 1c . Neither fast-food nor healthful food resource availability were associated with change in HbA 1c . Greater healthful food resource availability reduced the rate of increase in HbA 1c concentration attributed to the overweight

  12. How embarrassing! The behavioral and neural correlates of processing social norm violations

    PubMed Central

    van Steenbergen, Henk; Kreuk, Tanja; van der Wee, Nic J. A.; Westenberg, P. Michiel

    2017-01-01

    Social norms are important for human social interactions, and violations of these norms are evaluated partly on the intention of the actor. Here, we describe the revised Social Norm Processing Task (SNPT-R), a paradigm enabling the study of behavioral and neural responses to intended and unintended social norm violations among both adults and adolescents. We investigated how participants (adolescents and adults, n = 87) rate intentional and unintentional social norm violations with respect to inappropriateness and embarrassment, and we examined the brain activation patterns underlying the processing of these transgressions in an independent sample of 21 adults using functional Magnetic Resonance Imaging (fMRI). We hypothesized to find activation within the medial prefrontal cortex, temporo-parietal cortex and orbitofrontal cortex in response to both intentional and unintentional social norm violations, with more pronounced activation for the intentional social norm violations in these regions and in the amygdala. Participants’ ratings confirmed the hypothesis that the three types of stories are evaluated differently with respect to intentionality: intentional social norm violations were rated as the most inappropriate and most embarrassing. Furthermore, fMRI results showed that reading stories on intentional and unintentional social norm violations evoked activation within the frontal pole, the paracingulate gyrus and the superior frontal gyrus. In addition, processing unintentional social norm violations was associated with activation in, among others, the orbitofrontal cortex, middle frontal gyrus and superior parietal lobule, while reading intentional social norm violations was related to activation in the left amygdala. These regions have been previously implicated in thinking about one’s self, thinking about others and moral reasoning. Together, these findings indicate that the SNPT-R could serve as a useful paradigm for examining social norm processing

  13. A Modified CIPW Norm Calculation for Lunar Mare Basalts

    NASA Technical Reports Server (NTRS)

    Milliken, R. E.; Basu, A.

    2000-01-01

    CIPW norms of lunar mare basalts are anomalously low in pyroxene. A modified norm calculation allowing higher Ca, Ti, Al, Cr, and Mn in di' and hy' obtains closer matches between normative and modal mineralogy.

  14. Positive Neighborhood Norms Buffer Ethnic Diversity Effects on Neighborhood Dissatisfaction, Perceived Neighborhood Disadvantage, and Moving Intentions.

    PubMed

    Van Assche, Jasper; Asbrock, Frank; Roets, Arne; Kauff, Mathias

    2018-05-01

    Positive neighborhood norms, such as strong local networks, are critical to people's satisfaction with, perceived disadvantage of, and intentions to stay in their neighborhood. At the same time, local ethnic diversity is said to be detrimental for these community outcomes. Integrating both frameworks, we tested whether the negative consequences of diversity occur even when perceived social norms are positive. Study 1 ( N = 1,760 German adults) showed that perceptions of positive neighborhood norms buffered against the effects of perceived diversity on moving intentions via neighborhood satisfaction and perceived neighborhood disadvantage. Study 2 ( N = 993 Dutch adults) replicated and extended this moderated mediation model using other characteristics of diversity (i.e., objective and estimated minority proportions). Multilevel analyses again revealed consistent buffering effects of positive neighborhood norms. Our findings are discussed in light of the ongoing public and political debate concerning diversity and social and communal life.

  15. The attitude-behavior relationship in consumer conduct: the role of norms, past behavior, and self-identity.

    PubMed

    Smith, Joanne R; Terry, Deborah J; Manstead, Antony S R; Louis, Winnifred R; Kotterman, Diana; Wolfs, Jacqueline

    2008-06-01

    The authors used a revised planned behavior model in the consumer domain. The revised model incorporated separate measures of descriptive and injunctive/ prescriptive norms, self-identity, and past behavior in an effort to improve the predictive power of the theory of planned behavior (TPB; I. Ajzen, 1985) in relation to a self-reported consumer behavior: purchasing one's preferred soft drink. At Time 1, respondents (N = 112) completed self-report measures of (a) attitudes, (b) perceived behavioral control, (c) descriptive and injunctive/prescriptive norms, (d) self-identity, (e) past behavior, and (f) intentions. The authors assessed self-reported behavior 1 week later (Time 2). Attitudes, injunctive/prescriptive norms, descriptive norms, past behavior, and self-identity were all positively related to purchase intentions, and intentions were predictive of self-reported behavior at Time 2. These findings highlight the utility of the TPB in the consumer domain.

  16. A case study on the formation and sharing process of science classroom norms

    NASA Astrophysics Data System (ADS)

    Chang, Jina; Song, Jinwoong

    2016-03-01

    The teaching and learning of science in school are influenced by various factors, including both individual factors, such as member beliefs, and social factors, such as the power structure of the class. To understand this complex context affected by various factors in schools, we investigated the formation and sharing process of science classroom norms in connection with these factors. By examining the developmental process of science classroom norms, we identified how the norms were realized, shared, and internalized among the members. We collected data through classroom observations and interviews focusing on two elementary science classrooms in Korea. From these data, factors influencing norm formation were extracted and developed as stories about norm establishment. The results indicate that every science classroom norm was established, shared, and internalized differently according to the values ingrained in the norms, the agent of norm formation, and the members' understanding about the norm itself. The desirable norms originating from values in science education, such as having an inquiring mind, were not established spontaneously by students, but were instead established through well-organized norm networks to encourage concrete practice. Educational implications were discussed in terms of the practice of school science inquiry, cultural studies, and value-oriented education.

  17. Injunctive Social Norms Primacy over Descriptive Social Norms in Retirement Savings Decisions

    ERIC Educational Resources Information Center

    Croy, Gerry; Gerrans, Paul; Speelman, Craig

    2010-01-01

    Consistent with the global trend to shift responsibility for retirement income provision from the public purse to individuals has been encouragement to save more and to manage investment strategy. Analyzing data from 2,300 respondents to a randomly distributed questionnaire, this article focuses on the motivational importance of social norms. The…

  18. Does Physical Activity Mediate the Associations Between Local-Area Descriptive Norms, Built Environment Walkability, and Glycosylated Hemoglobin?

    PubMed

    Carroll, Suzanne J; Niyonsenga, Theo; Coffee, Neil T; Taylor, Anne W; Daniel, Mark

    2017-08-23

    Associations between local-area residential features and glycosylated hemoglobin (HbA 1c ) may be mediated by individual-level health behaviors. Such indirect effects have rarely been tested. This study assessed whether individual-level self-reported physical activity mediated the influence of local-area descriptive norms and objectively expressed walkability on 10-year change in HbA 1c . HbA 1c was assessed three times for adults in a 10-year population-based biomedical cohort ( n = 4056). Local-area norms specific to each participant were calculated, aggregating responses from a separate statewide surveillance survey for 1600 m road-network buffers centered on participant addresses (local prevalence of overweight/obesity (body mass index ≥25 kg/m²) and physical inactivity (<150 min/week)). Separate latent growth models estimated direct and indirect (through physical activity) effects of local-area exposures on change in HbA 1c , accounting for spatial clustering and covariates (individual-level age, sex, smoking status, marital status, employment and education, and area-level median household income). HbA 1c worsened over time. Local-area norms directly and indirectly predicted worsening HbA 1c trajectories. Walkability was directly and indirectly protective of worsening HbA 1c . Local-area descriptive norms and walkability influence cardiometabolic risk trajectory through individual-level physical activity. Efforts to reduce population cardiometabolic risk should consider the extent of local-area unhealthful behavioral norms and walkability in tailoring strategies to improve physical activity.

  19. Does Physical Activity Mediate the Associations between Local-Area Descriptive Norms, Built Environment Walkability, and Glycosylated Hemoglobin?

    PubMed Central

    Daniel, Mark

    2017-01-01

    Associations between local-area residential features and glycosylated hemoglobin (HbA1c) may be mediated by individual-level health behaviors. Such indirect effects have rarely been tested. This study assessed whether individual-level self-reported physical activity mediated the influence of local-area descriptive norms and objectively expressed walkability on 10-year change in HbA1c. HbA1c was assessed three times for adults in a 10-year population-based biomedical cohort (n = 4056). Local-area norms specific to each participant were calculated, aggregating responses from a separate statewide surveillance survey for 1600 m road-network buffers centered on participant addresses (local prevalence of overweight/obesity (body mass index ≥25 kg/m2) and physical inactivity (<150 min/week)). Separate latent growth models estimated direct and indirect (through physical activity) effects of local-area exposures on change in HbA1c, accounting for spatial clustering and covariates (individual-level age, sex, smoking status, marital status, employment and education, and area-level median household income). HbA1c worsened over time. Local-area norms directly and indirectly predicted worsening HbA1c trajectories. Walkability was directly and indirectly protective of worsening HbA1c. Local-area descriptive norms and walkability influence cardiometabolic risk trajectory through individual-level physical activity. Efforts to reduce population cardiometabolic risk should consider the extent of local-area unhealthful behavioral norms and walkability in tailoring strategies to improve physical activity. PMID:28832552

  20. Using the RxNorm Web Services API for Quality Assurance Purposes

    PubMed Central

    Peters, Lee; Bodenreider, Olivier

    2008-01-01

    Auditing large, rapidly evolving terminological systems is still a challenge. In the case of RxNorm, a standardized nomenclature for clinical drugs, we argue that quality assurance processes can benefit from the recently released application programming interface (API) provided by RxNav. We demonstrate the usefulness of the API by performing a systematic comparison of alternative paths in the RxNorm graph, over several thousands of drug entities. This study revealed potential errors in RxNorm, currently under review. The results also prompted us to modify the implementation of RxNav to navigate the RxNorm graph more accurately. The RxNorm web services API used in this experiment is robust and fast. PMID:18999038

  1. Attitude Ambivalence, Friend Norms, and Adolescent Drug Use

    PubMed Central

    Hohman, Zachary P.; Crano, William D.; Siegel, Jason T.; Alvaro, Eusebio M.

    2013-01-01

    This study assessed the moderating effects of attitudinal ambivalence on adolescent marijuana use in the context of the theory of planned behavior (TPB). With data from the National Survey of Parents and Youth (N=1,604), two hierarchical multiple regression models were developed to examine the association of ambivalent attitudes, intentions, and later marijuana use. The first model explored the moderating effect of ambivalence on intentions to use marijuana; the second tested the moderation of ambivalence on actual marijuana use 1 year later. Results across both analyses suggest that ambivalence moderated the association of friend norms and subsequent adolescent marijuana use: friend norms were better predictors of marijuana intentions (β=0.151, t=2.29, p=0.02) and subsequent use when adolescents were attitudinally ambivalent about marijuana use (β=0.071, t=2.76, p= 0.006). These results suggest that preventive programs that affect the certainty with which adolescents holds pro- or antimarijuana attitudes may influence the likelihood of their resistance to, initiation, or continuance of marijuana use. PMID:23404670

  2. Attitude ambivalence, friend norms, and adolescent drug use.

    PubMed

    Hohman, Zachary P; Crano, William D; Siegel, Jason T; Alvaro, Eusebio M

    2014-02-01

    This study assessed the moderating effects of attitudinal ambivalence on adolescent marijuana use in the context of the theory of planned behavior (TPB). With data from the National Survey of Parents and Youth (N = 1,604), two hierarchical multiple regression models were developed to examine the association of ambivalent attitudes, intentions, and later marijuana use. The first model explored the moderating effect of ambivalence on intentions to use marijuana; the second tested the moderation of ambivalence on actual marijuana use 1 year later. Results across both analyses suggest that ambivalence moderated the association of friend norms and subsequent adolescent marijuana use: friend norms were better predictors of marijuana intentions (β = 0.151, t = 2.29, p = 0.02) and subsequent use when adolescents were attitudinally ambivalent about marijuana use (β = 0.071, t = 2.76, p = 0.006). These results suggest that preventive programs that affect the certainty with which adolescents holds pro- or antimarijuana attitudes may influence the likelihood of their resistance to, initiation, or continuance of marijuana use.

  3. Punish and voice: punishment enhances cooperation when combined with norm-signalling.

    PubMed

    Andrighetto, Giulia; Brandts, Jordi; Conte, Rosaria; Sabater-Mir, Jordi; Solaz, Hector; Villatoro, Daniel

    2013-01-01

    Material punishment has been suggested to play a key role in sustaining human cooperation. Experimental findings, however, show that inflicting mere material costs does not always increase cooperation and may even have detrimental effects. Indeed, ethnographic evidence suggests that the most typical punishing strategies in human ecologies (e.g., gossip, derision, blame and criticism) naturally combine normative information with material punishment. Using laboratory experiments with humans, we show that the interaction of norm communication and material punishment leads to higher and more stable cooperation at a lower cost for the group than when used separately. In this work, we argue and provide experimental evidence that successful human cooperation is the outcome of the interaction between instrumental decision-making and the norm psychology humans are provided with. Norm psychology is a cognitive machinery to detect and reason upon norms that is characterized by a salience mechanism devoted to track how much a norm is prominent within a group. We test our hypothesis both in the laboratory and with an agent-based model. The agent-based model incorporates fundamental aspects of norm psychology absent from previous work. The combination of these methods allows us to provide an explanation for the proximate mechanisms behind the observed cooperative behaviour. The consistency between the two sources of data supports our hypothesis that cooperation is a product of norm psychology solicited by norm-signalling and coercive devices.

  4. L1CAM in human cancer.

    PubMed

    Altevogt, Peter; Doberstein, Kai; Fogel, Mina

    2016-04-01

    L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system. Subsequent work discovered that L1CAM is expressed in many human cancers and is often associated with bad prognosis. This is most likely due to the motility and invasion promoting function of L1CAM. Here, we describe the path L1CAM has taken from a neural adhesion molecule to a recognized tumor antigen. We summarize the literature on L1CAM expression in cancers and pre-cancerous lesions. We focus on the genetic elements required for its re-expression and highlight preclinical studies for targeted therapy. The data suggest that L1CAM is a valuable diagnostic/prognostic marker and an attractive target for the therapy of several human cancers. © 2015 UICC.

  5. L2 Effects on L1 Event Conceptualization

    ERIC Educational Resources Information Center

    Bylund, Emanuel; Jarvis, Scott

    2011-01-01

    The finding that speakers of aspect languages encode event endpoints to a lesser extent than do speakers of non-aspect languages has led to the hypothesis that there is a relationship between grammatical aspect and event conceptualization (e.g., von Stutterheim and Nuse, 2003). The present study concerns L1 event conceptualization in 40 L1

  6. Descriptive drinking norms in Native American and non-Hispanic White college students.

    PubMed

    Hagler, Kylee J; Pearson, Matthew R; Venner, Kamilla L; Greenfield, Brenna L

    2017-09-01

    College students tend to overestimate how much their peers drink, which is associated with higher personal alcohol use. However, research has not yet examined if this phenomenon holds true among Native American (NA) college students. This study examined associations between descriptive norms and alcohol use/consequences in a sample of NA and non-Hispanic White (NHW) college students. NA (n=147, 78.6% female) and NHW (n=246, 67.8% female) undergraduates completed an online survey. NAs NHWs showed similar descriptive norms such that the "typical college student," "typical NA student," and "typical NHW student" were perceived to drink more than "best friends." "Best friends" descriptive norms (i.e., estimations of how many drinks per week were consumed by participants' best friends) were the most robust predictors of alcohol use/consequences. Effect size estimates of the associations between drinking norms and participants' alcohol use were consistently positive and ranged from r=0.25 to r=0.51 across the four reference groups. Negative binomial hurdle models revealed that all descriptive norms tended to predict drinking, and "best friends" drinking norms predicted alcohol consequences. Apart from one interaction effect, likely due to familywise error rate, these associations were not qualified by interactions with racial/ethnic group. We found similar patterns between NAs and NHWs both in the pattern of descriptive norms across reference groups and in the strength of associations between descriptive norms and alcohol use/consequences. Although these results suggest that descriptive norms operate similarly among NAs as other college students, additional research is needed to identify whether other norms (e.g., injunctive norms) operate similarly across NA and NHW students. Copyright © 2017. Published by Elsevier Ltd.

  7. easyCBM Norms. 2014 Edition. Technical Report #1409

    ERIC Educational Resources Information Center

    Saven, Jessica L.; Tindal, Gerald; Irvin, P. Shawn; Farley, Dan; Alonzo, Julie

    2014-01-01

    Previous norms for the easyCBM assessment system were computed using scores from all students who took each measure for every grade and benchmark season (fall, winter, and spring). During the 2013-­14 school year, new national norms were developed to more accurately (proportionately) represent reading and mathematics performance by two variables:…

  8. Norms governing urban African American adolescents’ sexual and substance-using behavior

    PubMed Central

    Dolcini, M. Margaret; Catania, Joseph A.; Harper, Gary W.; Watson, Susan E.; Ellen, Jonathan M.; Towner, Senna L.

    2013-01-01

    Using a probability-based neighborhood sample of urban African American youth and a sample of their close friends (N = 202), we conducted a one-year longitudinal study to examine key questions regarding sexual and drug using norms. The results provide validation of social norms governing sexual behavior, condom use, and substance use among friendship groups. These norms had strong to moderate homogeneity; and both normative strength and homogeneity were relatively stable over a one-year period independent of changes in group membership. The data further suggest that sex and substance using norms may operate as a normative set. Similar to studies of adults, we identified three distinct “norm-based” social strata in our sample. Together, our findings suggest that the norms investigated are valid targets for health promotion efforts, and such efforts may benefit from tailoring programs to the normative sets that make up the different social strata in a given adolescent community. PMID:23072891

  9. Young Children See a Single Action and Infer a Social Norm.

    PubMed

    Schmidt, Marco F H; Butler, Lucas P; Heinz, Julia; Tomasello, Michael

    2016-10-01

    Human social life depends heavily on social norms that prescribe and proscribe specific actions. Typically, young children learn social norms from adult instruction. In the work reported here, we showed that this is not the whole story: Three-year-old children are promiscuous normativists. In other words, they spontaneously inferred the presence of social norms even when an adult had done nothing to indicate such a norm in either language or behavior. And children of this age even went so far as to enforce these self-inferred norms when third parties "broke" them. These results suggest that children do not just passively acquire social norms from adult behavior and instruction; rather, they have a natural and proactive tendency to go from "is" to "ought." That is, children go from observed actions to prescribed actions and do not perceive them simply as guidelines for their own behavior but rather as objective normative rules applying to everyone equally.

  10. Social influence on temptation: perceived descriptive norms, temptation and restraint, and problem drinking among college students

    PubMed Central

    Rinker, Dipali Venkataraman; Neighbors, Clayton

    2013-01-01

    Temptation and restraint have long been associated with problematic drinking. Among college students, social norms are one of the strongest predictors of problematic drinking. To date, no studies have examined the association between temptation and restraint and perceived descriptive norms on drinking and alcohol-related problems among college students. The purpose of this study was to examine whether perceived descriptive norms moderated the relationship between temptation and restraint and drinking outcomes among college students. Participants were 1,095 college students from a large, public, culturally-diverse, southern university who completed an online survey about drinking behaviors and related attitudes. Drinks per week and alcohol-related problems were examined as a function of perceived descriptive norms, Cognitive Emotional Preoccupation (CEP) (temptation), and Cognitive Behavioral Control (CBC) (restraint). Additionally, drinking outcomes were examined as a function of the two-way interactions between CEP and perceived descriptive norms and CBC and perceived descriptive norms. Results indicated that CEP and perceived descriptive norms were associated with drinking outcomes. CBC was not associated with drinking outcomes. Additionally, perceived descriptive norms moderated the association between CEP and drinks per week and CEP and alcohol-related problems. There was a positive association between CEP and drinks per week and CEP and alcohol-related problems, especially for those higher on perceived descriptive norms. College students who are very tempted to drink may drink more heavily and experience alcohol-related problems more frequently if they have greater perceptions that the typical student at their university/college drinks a lot. PMID:24064190

  11. Social Norm, Family Communication, and HBV Screening among Asian Americans.

    PubMed

    Juon, Hee-Soon; Rimal, Rajiv N; Klassen, Ann; Lee, Sunmin

    2017-12-01

    Individuals' behaviors are influenced by those of others in their social environment (i.e., descriptive norms), as well as by how individuals perceive they should behave in that environment (e.g., injunctive norms). Although social norms are thought to play an important role in hepatitis B virus (HBV) screening, limited theoretical or empirical guidance exists on how the underlying process works. In addition, norms are social phenomena that are spread through family discussion about the importance of getting HBV screening. Using the theory of normative social behavior (TNSB), this study examined the roles of injunctive norms (IN), descriptive norms (DN), and family discussion in HBV screening behavior among Asian Americans. Data from a survey of Asian Americans in the Baltimore Washington metropolitan area (N = 877) were used to test underlying theoretical propositions. DN and family discussion emerged as key factors in HBV screening behavior among all Asian Americans. IN were associated with HBV screening among Chinese and Korean Americans, but not for Vietnamese Americans. Family discussion moderated the influence of DN on behavior among Chinese and Vietnamese Americans. However, the main effect of DN on screening behavior was not modified by IN (no interactions between DN and IN). The results indicate that family discussion and social norms are integral in enabling Asian Americans to undergo HBV screening and warrant sensitivity in the design and implementation of a liver cancer prevention program in this high-risk group of Asian Americans.

  12. Management of Naturally Occurring Radioactive Materials (NORM) in Canada

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Baweja, Anar S.; Tracy, Bliss L.

    2008-08-07

    In Canada, nuclear and radiological regulatory responsibilities are shared between the provinces/territories and the federal government. The Canadian Nuclear Safety Commission (CNSC) regulates nuclear fuel cycle materials and man-made radionuclides under the Nuclear Safety and Control Act (2000). The provinces and territories regulate NORM arising from industrial activities, not involving the nuclear fuel cycle materials. Present guideline--Canadian Guidelines for the Management of Naturally Occurring Radioactive Materials (NORM)--was published in 2000 in order to bring uniformity to the management of NORM-related procedures to provide adequate radiation protection for workers and the general public. The basic premise of these guidelines is thatmore » the NORM-related activities should not be posing any greater hazard than those activities regulated under the Nuclear Safety and Control Act; these concepts are described in this paper.« less

  13. European Top Managers' Age-Related Workplace Norms and Their Organizations' Recruitment and Retention Practices Regarding Older Workers.

    PubMed

    Oude Mulders, Jaap; Henkens, Kène; Schippers, Joop

    2017-10-01

    Top managers guide organizational strategy and practices, but their role in the employment of older workers is understudied. We study the effects that age-related workplace norms of top managers have on organizations' recruitment and retention practices regarding older workers. We investigate two types of age-related workplace norms, namely age equality norms (whether younger and older workers should be treated equally) and retirement age norms (when older workers are expected to retire) while controlling for organizational and national contexts. Data collected among top managers of 1,088 organizations from six European countries were used for the study. Logistic regression models were run to estimate the effects of age-related workplace norms on four different organizational outcomes: (a) recruiting older workers, (b) encouraging working until normal retirement age, (c) encouraging working beyond normal retirement age, and (d) rehiring retired former employees. Age-related workplace norms of top managers affect their organizations' practices, but in different ways. Age equality norms positively affect practices before the boundary of normal retirement age (Outcomes a and b), whereas retirement age norms positively affect practices after the boundary of normal retirement age (Outcomes c and d). Changing age-related workplace norms of important actors in organizations may be conducive to better employment opportunities and a higher level of employment participation of older workers. However, care should be taken to target the right types of norms, since targeting different norms may yield different outcomes. © The Author 2016. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  14. Norms of valence, arousal, and dominance for 13,915 English lemmas.

    PubMed

    Warriner, Amy Beth; Kuperman, Victor; Brysbaert, Marc

    2013-12-01

    Information about the affective meanings of words is used by researchers working on emotions and moods, word recognition and memory, and text-based sentiment analysis. Three components of emotions are traditionally distinguished: valence (the pleasantness of a stimulus), arousal (the intensity of emotion provoked by a stimulus), and dominance (the degree of control exerted by a stimulus). Thus far, nearly all research has been based on the ANEW norms collected by Bradley and Lang (1999) for 1,034 words. We extended that database to nearly 14,000 English lemmas, providing researchers with a much richer source of information, including gender, age, and educational differences in emotion norms. As an example of the new possibilities, we included stimuli from nearly all of the category norms (e.g., types of diseases, occupations, and taboo words) collected by Van Overschelde, Rawson, and Dunlosky (Journal of Memory and Language 50:289-335, 2004), making it possible to include affect in studies of semantic memory.

  15. Mechanism for the decrease in the FIP1L1-PDGFRalpha protein level in EoL-1 cells by histone deacetylase inhibitors.

    PubMed

    Ishihara, Kenji; Kaneko, Motoko; Kitamura, Hajime; Takahashi, Aki; Hong, Jang Ja; Seyama, Toshio; Iida, Koji; Wada, Hiroshi; Hirasawa, Noriyasu; Ohuchi, Kazuo

    2008-01-01

    Acetylation and deacetylation of proteins occur in cells in response to various stimuli, and are reversibly catalyzed by histone acetyltransferase and histone deacetylase (HDAC), respectively. EoL-1 cells have an FIP1L1-PDGFRA fusion gene that causes transformation of eosinophilic precursor cells into leukemia cells. The HDAC inhibitors apicidin and n-butyrate suppress the proliferation of EoL-1 cells and induce differentiation into eosinophils by a decrease in the protein level of FIP1L1-PDGFRalpha without affecting the mRNA level for FIP1L1-PDGFRA. In this study, we analyzed the mechanism by which the protein level of FIP1L1-PDGFRalpha is decreased by apicidin and n-butyrate. EoL-1 cells were incubated in the presence of the HDAC inhibitors apicidin, trichostatin A or n-butyrate. The protein levels of FIP1L1-PDGFRalpha and phosphorylated eIF-2alpha were determined by Western blotting. Actinomycin D and cycloheximide were used to block RNA synthesis and protein synthesis, respectively, in the chasing experiment of the amount of FIP1L1-PDGFRalpha protein. When apicidin- and n-butyrate-treated EoL-1 cells were incubated in the presence of actinomycin D, the decrease in the protein level of FIP1L1-PDGFRalpha was significantly enhanced when compared with controls. In contrast, the protein levels were not changed by cycloheximide among these groups. Apicidin and n-butyrate induced the continuous phosphorylation of eIF-2alpha for up to 8 days. The decrease in the level of FIP1L1-PDGFRalpha protein by continuous inhibition of HDAC may be due to the decrease in the translation rate of FIP1L1-PDGFRA. Copyright 2008 S. Karger AG, Basel.

  16. Relationship among values, beliefs, norms and ecological behaviour.

    PubMed

    González López, Antonio; Amérigo Cuervo-Arango, María

    2008-11-01

    The present study focuses mainly on the relationship between psychological constructs and ecological behaviour. Empirical analysis links personal values, ecological beliefs, consequences of environmental conditions, denial of ecological obligation, environmental control, personal norms and environment protection behaviour. Survey data from a path analysis of a Spanish sample of 403 individuals were used, showing that ecological beliefs, personal norms and eco-altruistic values have become the main psychological explanatory variables of environment protective behaviour. Ecological beliefs, when measured by the New Ecological Paradigm Scale, affected ecological behaviour decisively. Environmental and altruistic values were shown to be related to moral obligation, and a basic variable to understand behaviour. Personal norm mediated the effects of values and environmental control on ecological behaviour.

  17. Jimmy's baby doll and Jenny's truck: young children's reasoning about gender norms.

    PubMed

    Conry-Murray, Clare; Turiel, Elliot

    2012-01-01

    To assess the flexibility of reasoning about gender, children ages 4, 6, and 8 years (N = 72) were interviewed about gender norms when different domains were highlighted. The majority of participants at all ages judged a reversal of gender norms in a different cultural context to be acceptable. They also judged gender norms as a matter of personal choice and they negatively evaluated a rule enforcing gender norms in schools. Older children were more likely to show flexibility than younger children. Justifications obtained from 6- and 8-year-olds showed that they considered adherence to gender norms a matter of personal choice and they viewed the rule enforcing gender norms as unfair. © 2011 The Authors. Child Development © 2011 Society for Research in Child Development, Inc.

  18. Setting radon-specific release criteria and demonstrating compliance for land affected by NORM.

    PubMed

    García-Talavera, M; Martínez, M; Matarranz, J L M; Ramos, L

    2008-11-01

    Residues from industrial activities involving naturally occurring radioactive materials (NORMs) may cause radiation exposures to members of the public, particularly when NORM-affected land is brought into residential use. To provide an adequate protection against radiation in such situations, the following limiting criteria are currently required in Spain for releasing NORM-affected land: (i) no more than a 300 microSv yr(-1) increase (excluding radon doses) over the natural background; (ii) (222)Rn concentrations in hypothetical future dwellings lower than 200 Bq m(-3); and (iii) reduction of all radiation exposures to as low as reasonable achievable. This paper addresses some of the problems encountered in translating the (222)Rn criterion into site-specific release limits and in demonstrating compliance with them.

  19. Quantifying the Quality Difference between L1 and L2 Essays: A Rating Procedure with Bilingual Raters and L1 and L2 Benchmark Essays

    ERIC Educational Resources Information Center

    Tillema, Marion; van den Bergh, Huub; Rijlaarsdam, Gert; Sanders, Ted

    2013-01-01

    It is the consensus that, as a result of the extra constraints placed on working memory, texts written in a second language (L2) are usually of lower quality than texts written in the first language (L1) by the same writer. However, no method is currently available for quantifying the quality difference between L1 and L2 texts. In the present…

  20. Marketing Norm Perception Among Medical Representatives in Indian Pharmaceutical Industry

    PubMed Central

    Nagashekhara, Molugulu; Agil, Syed Omar Syed; Ramasamy, Ravindran

    2012-01-01

    Study of marketing norm perception among medical representatives is an under-portrayed component that deserves further perusal in the pharmaceutical industry. The purpose of this study is to find out the perception of marketing norms among medical representatives. The research design is quantitative and cross sectional study with medical representatives as unit of analysis. Data is collected from medical representatives (n=300) using a simple random and cluster sampling using a structured questionnaire. Results indicate that there is no difference in the perception of marketing norms among male and female medical representatives. But there is a difference in opinion among domestic and multinational company’s medical representatives. Educational back ground of medical representatives also shows the difference in opinion among medical representatives. Degree holders and multinational company medical representatives have high perception of marketing norms compare to their counterparts. The researchers strongly believe that mandatory training on marketing norms is beneficial in decision making process during the dilemmas in the sales field. PMID:24826035

  1. Fruit and Vegetable Attitudes, Norms, and Intake in Low-Income Youth.

    PubMed

    Di Noia, Jennifer; Cullen, Karen Weber

    2015-12-01

    Fruit and vegetable (FV) attitudes and norms have been shown to influence intake in youth; yet research with low-income youth and studies supplementing self-report with objective measures of intake are lacking. Cross-sectional survey data on self-rated FV intake, FV attitudes, and FV norms were collected in a sample of 116 youth attending a residential summer camp serving low-income families. FV intake also was estimated by direct observation. Differences between self-rated and observed FV intake, perceived and observed peer intake, and perceived and peer-reported attitudes toward eating FVs were assessed with paired samples t tests. The role of FV attitudes, descriptive norms (perceived peer FV intake), injunctive norms (perceived peer attitudes toward eating FVs), and actual norms (observed peer FV intake and peer-reported FV attitudes) in predicting FV intake also was examined with multiple regression analysis. Youth misperceived their own and their peers' FV intake (i.e., overestimated intake of fruit and underestimated intake of vegetables) and believed that peers held less favorable attitudes toward eating FVs than was the case. The models predicting self-rated intake were significant, accounting for 34% of the variance in fruit intake and 28% of the variance in vegetable intake. Attitudes and descriptive norms were positively associated with FV intake, and observed peer fruit intake was negatively associated with fruit intake. Findings suggest that in low-income youth, FV attitudes, descriptive norms, and normative peer behavior predict perceived but not actual intake. Youth may benefit from intervention to promote favorable FV attitudes and norms. A focus on descriptive norms holds promise for improving self-rated intake in this population. © 2015 Society for Public Health Education.

  2. $L_{0}$ Gradient Projection.

    PubMed

    Ono, Shunsuke

    2017-04-01

    Minimizing L 0 gradient, the number of the non-zero gradients of an image, together with a quadratic data-fidelity to an input image has been recognized as a powerful edge-preserving filtering method. However, the L 0 gradient minimization has an inherent difficulty: a user-given parameter controlling the degree of flatness does not have a physical meaning since the parameter just balances the relative importance of the L 0 gradient term to the quadratic data-fidelity term. As a result, the setting of the parameter is a troublesome work in the L 0 gradient minimization. To circumvent the difficulty, we propose a new edge-preserving filtering method with a novel use of the L 0 gradient. Our method is formulated as the minimization of the quadratic data-fidelity subject to the hard constraint that the L 0 gradient is less than a user-given parameter α . This strategy is much more intuitive than the L 0 gradient minimization because the parameter α has a clear meaning: the L 0 gradient value of the output image itself, so that one can directly impose a desired degree of flatness by α . We also provide an efficient algorithm based on the so-called alternating direction method of multipliers for computing an approximate solution of the nonconvex problem, where we decompose it into two subproblems and derive closed-form solutions to them. The advantages of our method are demonstrated through extensive experiments.

  3. The Quest for Quality--Towards Joint European Quality Norms.

    ERIC Educational Resources Information Center

    Bartholomeus, Yvonne, Ed.; And Others

    This book contains the following papers about considerations in developing joint European quality norms for vocational guidance: "Joint Quality Norms in Guidance"; "Careers Guidance in the Information Society" (Frans Meijers); "The Changing Nature of Guidance" (J. Chamberlain); "Quality with Policy: Beyond…

  4. PD-L1 gene polymorphisms and low serum level of PD-L1 protein are associated to type 1 diabetes in Chile.

    PubMed

    Pizarro, Carolina; García-Díaz, Diego F; Codner, Ethel; Salas-Pérez, Francisca; Carrasco, Elena; Pérez-Bravo, Francisco

    2014-11-01

    Type 1 diabetes (T1D) has a complex etiology in which genetic and environmental factors are involved, whose interactions have not yet been completely clarified. In this context, the role in PD-1 pathway and its ligands 1 and 2 (PD-L1 and PD-L2) have been proposed as candidates in several autoimmune diseases. The aim of this work was to determine the allele and haplotype frequency of six gene polymorphisms of PD-ligands (PD-L1 and PD-L2) in Chilean T1D patients and their effect on serum levels of PD-L1 and autoantibody profile (GAD65 and IA2). This study cohort comprised 205 T1D patients and 205 normal children. We performed genotypic analysis of PD-L1 and PD-L2 genes by TaqMan method. Determination of anti-GAD65 and anti-IA-2 autoantibodies was performed by ELISA. The PD-L1 serum levels were measured. The allelic distribution of PD-L1 variants (rs2297137 and rs4143815) showed differences between T1D patients and controls (p = 0.035 and p = 0.022, respectively). No differences were detected among the PD-L2 polymorphisms, and only the rs16923189 showed genetic variation. T1D patients showed decreased serum levels of PD-L1 compared to controls: 1.42 [0.23-7.45] ng/mL versus 3.35 [0.49-5.89] ng/mL (p < 0.025). In addition, the CGG haplotype in PD-L1 associated with T1D (constructed from rs822342, rs2297137 and rs4143815 polymorphisms) showed an OR = 1.44 [1.08 to 1.93]. Finally, no association of these genetic variants was observed with serum concentrations of PD ligands or auto-antibody profile, although a correlation between PD-L1 ligand serum concentration and the age at disease onset was detected. Two polymorphism of PD-L1 are presented in different allelic variants between T1D and healthy subjects, also PDL-1 serum levels are significantly lowered in diabetics patients. Moreover, the age of onset of the disease determine differences between serum ligand levels in diabetics, being lower in younger. These results points to a possible establishment of

  5. Threshold to Transfer Writing Skills from L1 to L2

    ERIC Educational Resources Information Center

    Ito, Fumihiko

    2009-01-01

    Background: It has been hypothesized that L2 (second language) readers are not able to draw on their L1 (first language) reading skills for the successful development of L2 reading skills until they develop a certain proficiency in L2 because a lack of proficiency blocks transfer of L1 reading skills to the reading of L2 texts. This minimum degree…

  6. Punish and Voice: Punishment Enhances Cooperation when Combined with Norm-Signalling

    PubMed Central

    Andrighetto, Giulia; Brandts, Jordi; Conte, Rosaria; Sabater-Mir, Jordi; Solaz, Hector; Villatoro, Daniel

    2013-01-01

    Material punishment has been suggested to play a key role in sustaining human cooperation. Experimental findings, however, show that inflicting mere material costs does not always increase cooperation and may even have detrimental effects. Indeed, ethnographic evidence suggests that the most typical punishing strategies in human ecologies (e.g., gossip, derision, blame and criticism) naturally combine normative information with material punishment. Using laboratory experiments with humans, we show that the interaction of norm communication and material punishment leads to higher and more stable cooperation at a lower cost for the group than when used separately. In this work, we argue and provide experimental evidence that successful human cooperation is the outcome of the interaction between instrumental decision-making and the norm psychology humans are provided with. Norm psychology is a cognitive machinery to detect and reason upon norms that is characterized by a salience mechanism devoted to track how much a norm is prominent within a group. We test our hypothesis both in the laboratory and with an agent-based model. The agent-based model incorporates fundamental aspects of norm psychology absent from previous work. The combination of these methods allows us to provide an explanation for the proximate mechanisms behind the observed cooperative behaviour. The consistency between the two sources of data supports our hypothesis that cooperation is a product of norm psychology solicited by norm-signalling and coercive devices. PMID:23776441

  7. True gender ratios and stereotype rating norms

    PubMed Central

    Garnham, Alan; Doehren, Sam; Gygax, Pascal

    2015-01-01

    We present a study comparing, in English, perceived distributions of men and women in 422 named occupations with actual real world distributions. The first set of data was obtained from previous a large-scale norming study, whereas the second set was mostly drawn from UK governmental sources. In total, real world ratios for 290 occupations were obtained for our perceive vs. real world comparison, of which 205 were deemed to be unproblematic. The means for the two sources were similar and the correlation between them was high, suggesting that people are generally accurate at judging real gender ratios, though there were some notable exceptions. Beside this correlation, some interesting patterns emerged from the two sources, suggesting some response strategies when people complete norming studies. We discuss these patterns in terms of the way real world data might complement norming studies in determining gender stereotypicality. PMID:26257681

  8. Social norm enforcement in ethnically diverse communities

    PubMed Central

    Zhang, Nan

    2018-01-01

    Recent waves of immigration to Western nations have fueled a debate over the consequences of ethnic diversity for social cohesion. One prominent argument in this debate holds that diversity is detrimental to trust and cooperation because individuals in heterogeneous communities face difficulties in enforcing social norms across ethnic lines. We examine this proposition in a field experiment involving real-life interactions among residents of multiethnic German neighborhoods. We find significant ethnic asymmetries in the pattern of norm enforcement: Members of the majority “native” German population are more active in sanctioning norm violations, while ethnic minorities are more likely to find themselves the target of sanctions. We interpret these results in light of prevailing status inequalities between ethnic minorities and the native majority. We further calculate that, as a result of ethnic discrimination, social control is likely to rise in communities with moderate minority population shares. PMID:29483253

  9. Enabling phenotypic big data with PheNorm.

    PubMed

    Yu, Sheng; Ma, Yumeng; Gronsbell, Jessica; Cai, Tianrun; Ananthakrishnan, Ashwin N; Gainer, Vivian S; Churchill, Susanne E; Szolovits, Peter; Murphy, Shawn N; Kohane, Isaac S; Liao, Katherine P; Cai, Tianxi

    2018-01-01

    Electronic health record (EHR)-based phenotyping infers whether a patient has a disease based on the information in his or her EHR. A human-annotated training set with gold-standard disease status labels is usually required to build an algorithm for phenotyping based on a set of predictive features. The time intensiveness of annotation and feature curation severely limits the ability to achieve high-throughput phenotyping. While previous studies have successfully automated feature curation, annotation remains a major bottleneck. In this paper, we present PheNorm, a phenotyping algorithm that does not require expert-labeled samples for training. The most predictive features, such as the number of International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes or mentions of the target phenotype, are normalized to resemble a normal mixture distribution with high area under the receiver operating curve (AUC) for prediction. The transformed features are then denoised and combined into a score for accurate disease classification. We validated the accuracy of PheNorm with 4 phenotypes: coronary artery disease, rheumatoid arthritis, Crohn's disease, and ulcerative colitis. The AUCs of the PheNorm score reached 0.90, 0.94, 0.95, and 0.94 for the 4 phenotypes, respectively, which were comparable to the accuracy of supervised algorithms trained with sample sizes of 100-300, with no statistically significant difference. The accuracy of the PheNorm algorithms is on par with algorithms trained with annotated samples. PheNorm fully automates the generation of accurate phenotyping algorithms and demonstrates the capacity for EHR-driven annotations to scale to the next level - phenotypic big data. © The Author 2017. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  10. McCarthyism's Rhetorical Norms.

    ERIC Educational Resources Information Center

    Townsend, Rebecca M.

    Rhetorical norms of early McCarthyist discourse reveal a reliance upon images of chaos and the body. Through such metaphors, rhetors crafted a model of discussion that feminized "democracy" and "tolerance" to support anti-Communist measures and de-legitimize their opponents. Political variety was coded as deviant to national…

  11. Three cases with L1 syndrome and two novel mutations in the L1CAM gene.

    PubMed

    Marín, Rosario; Ley-Martos, Miriam; Gutiérrez, Gema; Rodríguez-Sánchez, Felicidad; Arroyo, Diego; Mora-López, Francisco

    2015-11-01

    Mutations in the L1CAM gene have been identified in the following various X-linked neurological disorders: congenital hydrocephalus; mental retardation, aphasia, shuffling gait, and adducted thumbs (MASA) syndrome; spastic paraplegia; and agenesis of the corpus callosum. These conditions are currently considered different phenotypes of a single entity known as L1 syndrome. We present three families with L1 syndrome. Sequencing of the L1CAM gene allowed the identification of the following mutations involved: a known splicing mutation (c.3531-12G>A) and two novel ones: a missense mutation (c.1754A>C; p.Asp585Ala) and a nonsense mutation (c.3478C>T; p.Gln1160Stop). The number of affected males and carrier females identified in a relatively small population suggests that L1 syndrome may be under-diagnosed. L1 syndrome should be considered in the differential diagnosis of intellectual disability or mental retardation in children, especially when other signs such as hydrocephalus or adducted thumbs are present.

  12. Social norms and family planning decisions in South Sudan.

    PubMed

    Kane, Sumit; Kok, Maryse; Rial, Matilda; Matere, Anthony; Dieleman, Marjolein; Broerse, Jacqueline Ew

    2016-11-22

    With a maternal mortality ratio of 789 per 100,000 live births, and a contraceptive prevalence rate of 4.7%, South Sudan has one of the worst reproductive health situations in the world. Understanding the social norms around sexuality and reproduction, across different ethnic groups, is key to developing and implementing locally appropriate public health responses. A qualitative study was conducted in the state of Western Bahr el Ghazal (WBeG) in South Sudan to explore the social norms shaping decisions about family planning among the Fertit community. Data were collected through five focus group discussions and 44 semi-structured interviews conducted with purposefully selected community members and health personnel. Among the Fertit community, the social norm which expects people to have as many children as possible remains well established. It is, however, under competitive pressure from the existing norm which makes spacing of pregnancies socially desirable. Young Fertit women are increasingly, either covertly or overtly, making family planning decisions themselves; with resistance from some menfolk, but also support from others. The social norm of having as many children as possible is also under competitive pressure from the emerging norm that equates taking good care of one's children with providing them with a good education. The return of peace and stability in South Sudan, and people's aspirations for freedom and a better life, is creating opportunities for men and women to challenge and subvert existing social norms, including but not limited to those affecting reproductive health, for the better. The sexual and reproductive health programmes in WBeG should work with and leverage existing and emerging social norms on spacing in their health promotion activities. Campaigns should focus on promoting a family ideal in which children become the object of parental investment, rather than labour to till the land - instead of focusing directly or solely on

  13. Civility norms, safety climate, and safety outcomes: a preliminary investigation.

    PubMed

    McGonagle, Alyssa K; Walsh, Benjamin M; Kath, Lisa M; Morrow, Stephanie L

    2014-10-01

    Working environments that are both civil and safe are good for business and employee well-being. Civility has been empirically linked to such important outcomes as organizational performance and individuals' positive work-related attitudes, yet research relating civility to safety is lacking. In this study, we link perceptions of civility norms to perceptions of safety climate and safety outcomes. Drawing on social exchange theory, we proposed and tested a model in 2 samples wherein civility norms indirectly relate to safety outcomes through associations with various safety climate facets. Our results supported direct relationships between civility and management safety climate and coworker safety climate. Additionally, indirect effects of civility norms on unsafe behaviors and injuries were observed. Indirect effects of civility norms on unsafe behaviors were observed through coworker safety climate and work-safety tension. Indirect effects of civility norms on injuries were observed through management safety climate and work-safety tension for full-time employees, although these effects did not hold for part-time employees. This study provides initial evidence that researchers and practitioners may want to look beyond safety climate to civility norms to more comprehensively understand the origins of unsafe behaviors and injuries and to develop appropriate preventive interventions. (PsycINFO Database Record (c) 2014 APA, all rights reserved).

  14. Clothing norms as markers of status in a hospital setting: A Bourdieusian analysis.

    PubMed

    Jenkins, Tania M

    2014-09-01

    This article uses a Bourdieusian framework to understand the importance of clothing norms for symbolizing and reproducing social, as well as professional, hierarchy in hospitals. Using data from participant observation, it examines how a complex yet informal dress code has emerged at a community hospital in the Northeastern United States, in a setting where very few formal guidelines exist on how to dress. By conceptualizing professionals as holders of various types of capital (economic, cultural, and symbolic), this article expands previous research which considered clothing only as a marker of professional identity. The findings demonstrate (1) how clothing norms are used in subtle, but purposeful, ways to reflect varying degrees of cultural and economic capital and (2) how these complex norms also reflect professional boundaries in medical authority (symbolic capital), which is important during critical moments where clothing can quickly signal who can take control. The discussion borrows Bourdieu's concepts of habitus and field to explain why subordinates subscribe to these clothing norms, in the absence of a formal organizational dress code. © The Author(s) 2014.

  15. Assessing the effect of sodium dichloroisocyanurate concentration on transfer of Salmonella enterica serotype Typhimurium in wash water for production of minimally processed iceberg lettuce (Lactuca sativa L.).

    PubMed

    Maffei, D F; Sant'Ana, A S; Monteiro, G; Schaffner, D W; Franco, B D G M

    2016-06-01

    This study evaluated the impact of sodium dichloroisocyanurate (5, 10, 20, 30, 40, 50 and 250 mg l(-1) ) in wash water on transfer of Salmonella Typhimurium from contaminated lettuce to wash water and then to other noncontaminated lettuces washed sequentially in the same water. Experiments were designed mimicking the conditions commonly seen in minimally processed vegetable (MPV) processing plants in Brazil. The scenarios were as follows: (1) Washing one inoculated lettuce portion in nonchlorinated water, followed by washing 10 noninoculated portions sequentially. (2) Washing one inoculated lettuce portion in chlorinated water followed by washing five noninoculated portions sequentially. (3) Washing five inoculated lettuce portions in chlorinated water sequentially, followed by washing five noninoculated portions sequentially. (4) Washing five noninoculated lettuce portions in chlorinated water sequentially, followed by washing five inoculated portions sequentially and then by washing five noninoculated portions sequentially in the same water. Salm. Typhimurium transfer from inoculated lettuce to wash water and further dissemination to noninoculated lettuces occurred when nonchlorinated water was used (scenario 1). When chlorinated water was used (scenarios 2, 3 and 4), no measurable Salm. Typhimurium transfer occurred if the sanitizer was ≥10 mg l(-1) . Use of sanitizers in correct concentrations is important to minimize the risk of microbial transfer during MPV washing. In this study, the impact of sodium dichloroisocyanurate in the wash water on transfer of Salmonella Typhimurium from inoculated lettuce to wash water and then to other noninoculated lettuces washed sequentially in the same water was evaluated. The use of chlorinated water, at concentration above 10 mg l(-1) , effectively prevented Salm. Typhimurium transfer under several different washing scenarios. Conversely, when nonchlorinated water was used, Salm. Typhimurium transfer occurred in

  16. Descriptive peer norms, self-control and dietary behaviour in young adults.

    PubMed

    Robinson, Eric; Otten, Roy; Hermans, Roel C J

    2016-01-01

    There is evidence that perceived peer eating norms can influence dietary behaviour. This cross-sectional study examined whether certain personality traits increase the likelihood that personal eating habits are similar to perceived peer eating habits. We assessed frequency of consumption of sugar-sweetened soda (SSS) and sweet pastries (SP), as well as perceived peer descriptive eating norms for SSS and SP in a group of 1056 young adults. We examined whether individual differences in the need for social acceptance and self-control moderated whether participants were likely to display similar dietary habits to their peers. Perceived peer eating norms for SSS and SP predicted frequency of consumption; believing that one's peers frequently consumed SSS and SP was associated with increased personal consumption for both. Individuals with low self-control, as opposed to high self-control, were more likely to adhere to peer norms for SP, but not for SSS. Trait social acceptance needs did not significantly moderate similarity between peer norms and personal consumption for either SSS or SP. The extent to which young adults adhere to descriptive peer dietary norms may depend upon self-control, whereby individuals with low self-control are less able to inhibit social influence of descriptive peer norms on dietary behaviour.

  17. The Relationship between L1 Fluency and L2 Fluency Development

    ERIC Educational Resources Information Center

    Derwing, Tracey M.; Munro, Murray J.; Thomson, Ronald I.; Rossiter, Marian J.

    2009-01-01

    A fundamental question in the study of second language (L2) fluency is the extent to which temporal characteristics of speakers' first language (L1) productions predict the same characteristics in the L2. A close relationship between a speaker's L1 and L2 temporal characteristics would suggest that fluency is governed by an underlying trait. This…

  18. Designing feedback to mitigate teen distracted driving: A social norms approach.

    PubMed

    Merrikhpour, Maryam; Donmez, Birsen

    2017-07-01

    The purpose of this research is to investigate teens' perceived social norms and whether providing normative information can reduce distracted driving behaviors among them. Parents are among the most important social referents for teens; they have significant influences on teens' driving behaviors, including distracted driving which significantly contributes to teens' crash risks. Social norms interventions have been successfully applied in various domains including driving; however, this approach is yet to be explored for mitigating driver distraction among teens. Forty teens completed a driving simulator experiment while performing a self-paced visual-manual secondary task in four between-subject conditions: a) social norms feedback that provided a report at the end of each drive on teens' distracted driving behavior, comparing their distraction engagement to their parent's, b) post-drive feedback that provided just the report on teens' distracted driving behavior without information on their parents, c) real-time feedback in the form of auditory warnings based on eyes of road-time, and d) no feedback as control. Questionnaires were administered to collect data on these teens' and their parents' self-reported engagement in driver distractions and the associated social norms. Social norms and real-time feedback conditions resulted in significantly smaller average off-road glance duration, rate of long (>2s) off-road glances, and standard deviation of lane position compared to no feedback. Further, social norms feedback decreased brake response time and percentage of time not looking at the road compared to no feedback. No major effect was observed for post-drive feedback. Questionnaire results suggest that teens appeared to overestimate parental norms, but no effect of feedback was found on their perceptions. Feedback systems that leverage social norms can help mitigate driver distraction among teens. Overall, both social norms and real-time feedback induced

  19. The hitchhiker's guide to altruism: gene-culture coevolution, and the internalization of norms.

    PubMed

    Gintis, Herbert

    2003-02-21

    An internal norm is a pattern of behavior enforced in part by internal sanctions, such as shame, guilt and loss of self-esteem, as opposed to purely external sanctions, such as material rewards and punishment. The ability to internalize norms is widespread among humans, although in some so-called "sociopaths", this capacity is diminished or lacking. Suppose there is one genetic locus that controls the capacity to internalize norms. This model shows that if an internal norm is fitness enhancing, then for plausible patterns of socialization, the allele for internalization of norms is evolutionarily stable. This framework can be used to model Herbert Simon's (1990) explanation of altruism, showing that altruistic norms can "hitchhike" on the general tendency of internal norms to be personally fitness-enhancing. A multi-level selection, gene-culture coevolution argument then explains why individually fitness-reducing internal norms are likely to be prosocial as opposed to socially harmful.

  20. [Construction and application of prokaryotic expression system of Leptospira interrogans lipL32/1-lipL41/1 fusion gene].

    PubMed

    Luo, Dong-jiao; Yan, Jie; Mao, Ya-fei; Li, Shu-ping; Luo, Yi-hui; Li, Li-wei

    2005-01-01

    To construct lipL32/1-lipL41/1 fusion gene and its prokaryotic expression system and to determine frequencies of carrying and expression of lipL32 and lipL41 genes in L.interrogans wild strains and specific antibody levels in sera from leptospirosis patients. lipL32/1-lipL41/1 fusion gene was constructed using linking primer PCR method and the prokaryotic expression system of the fusion gene done with routine techniques. SDS-PAGE was used to examine expression of the target recombinant protein rLipL32/1-rLipL41/1. Immunogenicity of rLipL32/1-rLipL41/1 was identified by Western blot. PCR and MAT were performed to detect carrying and expression of lipL32 and lipL41 genes in 97 wild L.interrogans strains. Antibodies against products of lipL32 and lipL41 genes in serum samples from 228 leptospirosis patients were detected by ELISA method. The homogeneity of nucleotide and putative amino acid sequence of lipL32/1-lipL41/1 fusion gene were 99.9 % and 99.8 % in comparison with the reported sequences. Expression output of the target recombinant protein rLipL32/1-rLipL41/1, mainly present in inclusion body, accounted for 10 % of the total bacterial proteins. Both the rabbit antisera against rLipL32/1 and rLipL41/1 could combine to rLipL32/1-rLipL41/1. 97.9 % and 87.6 % of the L.interrogans wild strains had lipL32 and lipL41 genes, respectively. 95.9 % and 84.5 % of the wild strains were positive for MAT with titers of 1:4 - 1:128 using rabbit anti-rLipL32s or anti-rLipL41s sera, respectively. 94.7 % - 97.4 % of the patients'serum samples were positive for rLipL32s antibodies, while 78.5 % - 84.6 % of them were rLipL41s antibodies detectable. lipL32/1-jlipL41/1 fusion gene and its prokaryotic expression system were successfully constructed. The expressed fusion protein had qualified immunogenicity. Both the lipL32 and lipL41 genes are extensively carried and frequently expressed by different serogroups of L.interrogans, and their expression products exhibit cross-antigenicity.

  1. Descriptive Drinking Norms: For Whom Does Reference Group Matter?*

    PubMed Central

    Larimer, Mary E.; Neighbors, Clayton; LaBrie, Joseph W.; Atkins, David C.; Lewis, Melissa A.; Lee, Christine M.; Kilmer, Jason R.; Kaysen, Debra L.; Pedersen, Eric r.; Montoya, Heidi; Hodge, Kimberley; Desai, Sruti; Hummer, Justin F.; Walter, Theresa

    2011-01-01

    Objective: Perceived descriptive drinking norms often differ from actual norms and are positively related to personal consumption. However, it is not clear how normative perceptions vary with specificity of the reference group. Are drinking norms more accurate and more closely related to drinking behavior as reference group specificity increases? Do these relationships vary as a function of participant demographics? The present study examined the relationship between perceived descriptive norms and drinking behavior by ethnicity (Asian or White), sex, and fraternity/sorority status. Method: Participants were 2,699 (58% female) White (75%) or Asian (25%) undergraduates from two universities who reported their own alcohol use and perceived descriptive norms for eight reference groups: "typical student"; same sex, ethnicity, or fraternity/sorority status; and all combinations of these three factors. Results: Participants generally reported the highest perceived norms for the most distal reference group (typical student), with perceptions becoming more accurate as individuals' similarity to the reference group increased. Despite increased accuracy, participants perceived that all reference groups drank more than was actually the case. Across specific subgroups (fraternity/sorority members and men) different patterns emerged. Fraternity/sorority members reliably reported higher estimates of drinking for reference groups that included fraternity/ sorority status, and, to a lesser extent, men reported higher estimates for reference groups that included men. Conclusions: The results suggest that interventions targeting normative misperceptions may need to provide feedback based on participant demography or group membership. Although reference group-specific feedback may be important for some subgroups, typical student feedback provides the largest normative discrepancy for the majority of students. PMID:21906510

  2. Modulating PD-L1 expression in multiple myeloma: an alternative strategy to target the PD-1/PD-L1 pathway.

    PubMed

    Tremblay-LeMay, Rosemarie; Rastgoo, Nasrin; Chang, Hong

    2018-03-27

    Even with recent advances in therapy regimen, multiple myeloma patients commonly develop drug resistance and relapse. The relevance of targeting the PD-1/PD-L1 axis has been demonstrated in pre-clinical models. Monotherapy with PD-1 inhibitors produced disappointing results, but combinations with other drugs used in the treatment of multiple myeloma seemed promising, and clinical trials are ongoing. However, there have recently been concerns about the safety of PD-1 and PD-L1 inhibitors combined with immunomodulators in the treatment of multiple myeloma, and several trials have been suspended. There is therefore a need for alternative combinations of drugs or different approaches to target this pathway. Protein expression of PD-L1 on cancer cells, including in multiple myeloma, has been associated with intrinsic aggressive features independent of immune evasion mechanisms, thereby providing a rationale for the adoption of new strategies directly targeting PD-L1 protein expression. Drugs modulating the transcriptional and post-transcriptional regulation of PD-L1 could represent new therapeutic strategies for the treatment of multiple myeloma, help potentiate the action of other drugs or be combined to PD-1/PD-L1 inhibitors in order to avoid the potentially problematic combination with immunomodulators. This review will focus on the pathophysiology of PD-L1 expression in multiple myeloma and drugs that have been shown to modulate this expression.

  3. Quasi-kernel polynomials and convergence results for quasi-minimal residual iterations

    NASA Technical Reports Server (NTRS)

    Freund, Roland W.

    1992-01-01

    Recently, Freund and Nachtigal have proposed a novel polynominal-based iteration, the quasi-minimal residual algorithm (QMR), for solving general nonsingular non-Hermitian linear systems. Motivated by the QMR method, we have introduced the general concept of quasi-kernel polynomials, and we have shown that the QMR algorithm is based on a particular instance of quasi-kernel polynomials. In this paper, we continue our study of quasi-kernel polynomials. In particular, we derive bounds for the norms of quasi-kernel polynomials. These results are then applied to obtain convergence theorems both for the QMR method and for a transpose-free variant of QMR, the TFQMR algorithm.

  4. Development and validation of an eating norms inventory. Americans' lay-beliefs about appropriate eating.

    PubMed

    Fisher, Robert J; Dubé, Laurette

    2011-10-01

    What do American adults believe about what, where, when, how much, and how often it is appropriate to eat? Such normative beliefs originate from family and friends through socialization processes, but they are also influenced by governments, educational institutions, and businesses. Norms therefore provide an important link between the social environment and individual attitudes and behaviors. This paper reports on five studies that identify, develop, and validate measures of normative beliefs about eating. In study 1 we use an inductive method to identify what American adults believe are appropriate or desirable eating behaviors. Studies 2 and 3 are used to purify and assess the discriminant and nomological validity of the proposed set of 18 unidimensional eating norms. Study 4 assesses predictive validity and finds that acting in a norm-consistent fashion is associated with lower Body Mass Index (BMI), and greater body satisfaction and subjective health. Study 5 assesses the underlying social desirability and perceived healthiness of the norms. Copyright © 2011 Elsevier Ltd. All rights reserved.

  5. The Role of Familiarity for Representations in Norm-Based Face Space

    PubMed Central

    Faerber, Stella J.; Kaufmann, Jürgen M.; Leder, Helmut; Martin, Eva Maria; Schweinberger, Stefan R.

    2016-01-01

    According to the norm-based version of the multidimensional face space model (nMDFS, Valentine, 1991), any given face and its corresponding anti-face (which deviates from the norm in exactly opposite direction as the original face) should be equidistant to a hypothetical prototype face (norm), such that by definition face and anti-face should bear the same level of perceived typicality. However, it has been argued that familiarity affects perceived typicality and that representations of familiar faces are qualitatively different (e.g., more robust and image-independent) from those for unfamiliar faces. Here we investigated the role of face familiarity for rated typicality, using two frequently used operationalisations of typicality (deviation-based: DEV), and distinctiveness (face in the crowd: FITC) for faces of celebrities and their corresponding anti-faces. We further assessed attractiveness, likeability and trustworthiness ratings of the stimuli, which are potentially related to typicality. For unfamiliar faces and their corresponding anti-faces, in line with the predictions of the nMDFS, our results demonstrate comparable levels of perceived typicality (DEV). In contrast, familiar faces were perceived much less typical than their anti-faces. Furthermore, familiar faces were rated higher than their anti-faces in distinctiveness, attractiveness, likability and trustworthiness. These findings suggest that familiarity strongly affects the distribution of facial representations in norm-based face space. Overall, our study suggests (1) that familiarity needs to be considered in studies of mental representations of faces, and (2) that familiarity, general distance-to-norm and more specific vector directions in face space make different and interactive contributions to different types of facial evaluations. PMID:27168323

  6. The Role of Familiarity for Representations in Norm-Based Face Space.

    PubMed

    Faerber, Stella J; Kaufmann, Jürgen M; Leder, Helmut; Martin, Eva Maria; Schweinberger, Stefan R

    2016-01-01

    According to the norm-based version of the multidimensional face space model (nMDFS, Valentine, 1991), any given face and its corresponding anti-face (which deviates from the norm in exactly opposite direction as the original face) should be equidistant to a hypothetical prototype face (norm), such that by definition face and anti-face should bear the same level of perceived typicality. However, it has been argued that familiarity affects perceived typicality and that representations of familiar faces are qualitatively different (e.g., more robust and image-independent) from those for unfamiliar faces. Here we investigated the role of face familiarity for rated typicality, using two frequently used operationalisations of typicality (deviation-based: DEV), and distinctiveness (face in the crowd: FITC) for faces of celebrities and their corresponding anti-faces. We further assessed attractiveness, likeability and trustworthiness ratings of the stimuli, which are potentially related to typicality. For unfamiliar faces and their corresponding anti-faces, in line with the predictions of the nMDFS, our results demonstrate comparable levels of perceived typicality (DEV). In contrast, familiar faces were perceived much less typical than their anti-faces. Furthermore, familiar faces were rated higher than their anti-faces in distinctiveness, attractiveness, likability and trustworthiness. These findings suggest that familiarity strongly affects the distribution of facial representations in norm-based face space. Overall, our study suggests (1) that familiarity needs to be considered in studies of mental representations of faces, and (2) that familiarity, general distance-to-norm and more specific vector directions in face space make different and interactive contributions to different types of facial evaluations.

  7. L1 literacy affects L2 pronunciation intake and text vocalization

    NASA Astrophysics Data System (ADS)

    Walton, Martin

    2005-04-01

    For both deaf and hearing learners, L1 acquisition calls on auditive, gestural and visual modes in progressive processes over longer stages imposed in strictly anatomical and social order from the earliest pre-lexical phase [Jusczyk (1993), Kuhl & Meltzoff (1996)] to ultimate literacy. By contrast, L2 learning will call on accelerating procedures but with restricted input, arbitrated by L1 literacy as can be traced in the English of French-speaking learners, whether observed in spontaneous speech or in text vocalization modes. An inventory of their predictable omissions, intrusions and substitutions at suprasegmental and syllabic levels, many of which they can actually hear while unable to vocalize in real-time, suggests that a photogenic segmentation of continuous speech into alphabetical units has eclipsed the indispensable earlier phonogenic module, filtering L2 intake and output. This competing mode analysis hypothesizes a critical effect on L2 pronunciation of L1 graphemic procedures acquired usually before puberty, informing data for any Critical Period Hypothesis or amounts of L1 activation influencing L2 accent [Flege (1997, 1998)] or any psychoacoustic French deafness with regard to English stress-timing [Dupoux (1997)]. A metaphonic model [Howell & Dean (1991)] adapted for French learners may remedially distance L1 from L2 vocalization procedures.

  8. Psycholinguistic norms for 320 fixed expressions (idioms and proverbs) in French.

    PubMed

    Bonin, Patrick; Méot, Alain; Boucheix, Jean-Michel; Bugaiska, Aurélia

    2018-05-01

    We provide psycholinguistic norms for a new set of 160 French idiomatic expressions and 160 proverbs: knowledge, predictability, literality, compositionality, subjective and objective frequency, familiarity, age of acquisition (AoA) and length. Different analyses (reliability, descriptive statistics and correlations) performed on the norms are reported and discussed. The norms can be downloaded as Supplemental Material .

  9. Detection of high PD-L1 expression in oral cancers by a novel monoclonal antibody L1Mab-4.

    PubMed

    Yamada, Shinji; Itai, Shunsuke; Kaneko, Mika K; Kato, Yukinari

    2018-03-01

    Programmed cell death-ligand 1 (PD-L1), which is a ligand of programmed cell death-1 (PD-1), is a type I transmembrane glycoprotein that is expressed on antigen-presenting cells and several tumor cells, including melanoma and lung cancer cells. There is a strong correlation between human PD-L1 (hPD-L1) expression on tumor cells and negative prognosis in cancer patients. In this study, we produced a novel anti-hPD-L1 monoclonal antibody (mAb), L 1 Mab-4 (IgG 2b , kappa), using cell-based immunization and screening (CBIS) method and investigated hPD-L1 expression in oral cancers. L 1 Mab-4 reacted with oral cancer cell lines (Ca9-22, HO-1-u-1, SAS, HSC-2, HSC-3, and HSC-4) in flow cytometry and stained oral cancers in a membrane-staining pattern. L 1 Mab-4 stained 106/150 (70.7%) of oral squamous cell carcinomas, indicating the very high sensitivity of L 1 Mab-4. These results indicate that L 1 Mab-4 could be useful for investigating the function of hPD-L1 in oral cancers.

  10. Quadratic Optimization in the Problems of Active Control of Sound

    NASA Technical Reports Server (NTRS)

    Loncaric, J.; Tsynkov, S. V.; Bushnell, Dennis M. (Technical Monitor)

    2002-01-01

    We analyze the problem of suppressing the unwanted component of a time-harmonic acoustic field (noise) on a predetermined region of interest. The suppression is rendered by active means, i.e., by introducing the additional acoustic sources called controls that generate the appropriate anti-sound. Previously, we have obtained general solutions for active controls in both continuous and discrete formulations of the problem. We have also obtained optimal solutions that minimize the overall absolute acoustic source strength of active control sources. These optimal solutions happen to be particular layers of monopoles on the perimeter of the protected region. Mathematically, minimization of acoustic source strength is equivalent to minimization in the sense of L(sub 1). By contrast. in the current paper we formulate and study optimization problems that involve quadratic functions of merit. Specifically, we minimize the L(sub 2) norm of the control sources, and we consider both the unconstrained and constrained minimization. The unconstrained L(sub 2) minimization is certainly the easiest problem to address numerically. On the other hand, the constrained approach allows one to analyze sophisticated geometries. In a special case, we call compare our finite-difference optimal solutions to the continuous optimal solutions obtained previously using a semi-analytic technique. We also show that the optima obtained in the sense of L(sub 2) differ drastically from those obtained in the sense of L(sub 1).

  11. Sparse decomposition of seismic data and migration using Gaussian beams with nonzero initial curvature

    NASA Astrophysics Data System (ADS)

    Liu, Peng; Wang, Yanfei

    2018-04-01

    We study problems associated with seismic data decomposition and migration imaging. We first represent the seismic data utilizing Gaussian beam basis functions, which have nonzero curvature, and then consider the sparse decomposition technique. The sparse decomposition problem is an l0-norm constrained minimization problem. In solving the l0-norm minimization, a polynomial Radon transform is performed to achieve sparsity, and a fast gradient descent method is used to calculate the waveform functions. The waveform functions can subsequently be used for sparse Gaussian beam migration. Compared with traditional sparse Gaussian beam methods, the seismic data can be properly reconstructed employing fewer Gaussian beams with nonzero initial curvature. The migration approach described in this paper is more efficient than the traditional sparse Gaussian beam migration.

  12. Gender Norms and Retaliatory Violence against Spouses and Acquaintances

    ERIC Educational Resources Information Center

    Feld, Scott L.; Felson, Richard B.

    2008-01-01

    This article examines an experiment embedded within a nationally representative survey of adult Americans to investigate gender norms regarding retaliatory violence between spouses and acquaintances. Contrary to claims that societal norms permit violence within marriage, respondents disapproved of retaliatory violence against spouses more than…

  13. Minimal sulfated carbohydrates for recognition by L-selectin and the MECA-79 antibody.

    PubMed

    Bruehl, R E; Bertozzi, C R; Rosen, S D

    2000-10-20

    Sulfated forms of sialyl-Le(X) containing Gal-6-SO(4) or GlcNAc-6-SO(4) have been implicated as potential recognition determinants on high endothelial venule ligands for L-selectin. The optimal configuration of sulfate esters on the N-acetyllactosamine (Galbeta1-->4GlcNAc) core of sulfosialyl-Le(X), however, remains unsettled. Using a panel of sulfated lactose (Galbeta1-->4Glc) neoglycolipids as substrates in direct binding assays, we found that 6',6-disulfolactose was the preferred structure for L-selectin, although significant binding to 6'- and 6-sulfolactose was observed as well. Binding was EDTA-sensitive and blocked by L-selectin-specific monoclonal antibodies. Surprisingly, 6', 6-disulfolactose was poorly recognized by MECA-79, a carbohydrate- and sulfate-dependent monoclonal antibody that binds competitively to L-selectin ligands. Instead, MECA-79 bound preferentially to 6-sulfolactose. The difference in preferred substrates between L-selectin and MECA-79 may explain the variable activity of MECA-79 as an inhibitor of lymphocyte adhesion to high endothelial venules in lymphoid organs. Our results suggest that both Gal-6-SO(4) and GlcNAc-6-SO(4) may contribute to L-selectin recognition, either as components of sulfosialyl-Le(X) capping groups or in internal structures. By contrast, only GlcNAc-6-SO(4) appears to contribute to MECA-79 binding.

  14. Correlates of minimal dating.

    PubMed

    Leck, Kira

    2006-10-01

    Researchers have associated minimal dating with numerous factors. The present author tested shyness, introversion, physical attractiveness, performance evaluation, anxiety, social skill, social self-esteem, and loneliness to determine the nature of their relationships with 2 measures of self-reported minimal dating in a sample of 175 college students. For women, shyness, introversion, physical attractiveness, self-rated anxiety, social self-esteem, and loneliness correlated with 1 or both measures of minimal dating. For men, physical attractiveness, observer-rated social skill, social self-esteem, and loneliness correlated with 1 or both measures of minimal dating. The patterns of relationships were not identical for the 2 indicators of minimal dating, indicating the possibility that minimal dating is not a single construct as researchers previously believed. The present author discussed implications and suggestions for future researchers.

  15. Cultural differences in perceived social norms and social anxiety.

    PubMed

    Heinrichs, Nina; Rapee, Ronald M; Alden, Lynn A; Bögels, Susan; Hofmann, Stefan G; Oh, Kyung Ja; Sakano, Yuji

    2006-08-01

    Cultural considerations in social anxiety are a rarely investigated topic although it seems likely that differences between countries in social norms may relate to the extent of social anxiety. The present study investigated individuals' personal and perceived cultural norms and their relation to social anxiety and fear of blushing. A total of 909 participants from eight countries completed vignettes describing social situations and evaluated the social acceptability of the behavior of the main actor both from their own, personal perspective as well as from a cultural viewpoint. Personal and cultural norms showed somewhat different patterns in comparison between types of countries (individualistic/collectivistic). According to reported cultural norms, collectivistic countries were more accepting toward socially reticent and withdrawn behaviors than was the case in individualistic countries. In contrast, there was no difference between individualistic and collectivistic countries on individuals' personal perspectives regarding socially withdrawn behavior. Collectivistic countries also reported greater levels of social anxiety and more fear of blushing than individualistic countries. Significant positive relations occurred between the extent to which attention-avoiding behaviors are accepted in a culture and the level of social anxiety or fear of blushing symptoms. These results provide initial evidence that social anxiety may be related to different cultural norms across countries.

  16. The Centre for Speech, Language and the Brain (CSLB) concept property norms.

    PubMed

    Devereux, Barry J; Tyler, Lorraine K; Geertzen, Jeroen; Randall, Billi

    2014-12-01

    Theories of the representation and processing of concepts have been greatly enhanced by models based on information available in semantic property norms. This information relates both to the identity of the features produced in the norms and to their statistical properties. In this article, we introduce a new and large set of property norms that are designed to be a more flexible tool to meet the demands of many different disciplines interested in conceptual knowledge representation, from cognitive psychology to computational linguistics. As well as providing all features listed by 2 or more participants, we also show the considerable linguistic variation that underlies each normalized feature label and the number of participants who generated each variant. Our norms are highly comparable with the largest extant set (McRae, Cree, Seidenberg, & McNorgan, 2005) in terms of the number and distribution of features. In addition, we show how the norms give rise to a coherent category structure. We provide these norms in the hope that the greater detail available in the Centre for Speech, Language and the Brain norms should further promote the development of models of conceptual knowledge. The norms can be downloaded at www.csl.psychol.cam.ac.uk/propertynorms.

  17. L1 Explicit Instruction Can Improve L2 Online and Offline Performance

    ERIC Educational Resources Information Center

    McManus, Kevin; Marsden, Emma

    2017-01-01

    This study investigated the effectiveness of providing L1 explicit information (EI) with practice for making more accurate and faster interpretations of L2 French "Imparfait" (IMP). Two treatments were investigated: (a) "L2-only," providing EI about the L2 with L2 interpretation practice, and (b) "L2+L1," providing…

  18. Adolescents' physical activities and peer norms: the mediating role of self-efficacy.

    PubMed

    Lu, Frank J H; Lin, Ju-Han; Hsu, Ya-Wen; Chou, Chien-Chih; Wang, Erica T W; Yeh, Li-Chin

    2014-04-01

    The purpose of the present study was to examine the relations among adolescents' self-efficacy and social norms, and physical activity and whether self-efficacy mediated the relationship between social norms and physical activity. 400 junior high school students (202 boys, 198 girls, 2 not identified; M age = 15.3yr., SD = 0.6) completed a demographic questionnaire, the International Physical Activity Questionnaire (IPAQ), the Perceived Self-Efficacy in Physical Activity Scale, and the Physical Activity Social Norms Scale. Regression analyses indicated that both self-efficacy and social norms predicted physical activity. Self-efficacy fully mediated the relationship between peer norms and physical activity for boys but partially mediated the relationship for girls. An application of the results may be to foster self-efficacy and peer norms as a motivational strategy for supporting increased physical activity.

  19. Effects of Previous Fruit Intake, Descriptive Majority Norms, and Message Framing on Fruit Intake Intentions and Behaviors in Dutch Adults Across a 1-Week Period.

    PubMed

    de Bruijn, Gert-Jan; Visscher, Ilse; Mollen, Saar

    2015-01-01

    To test the effects of descriptive norm and message framing on fruit intake (intentions) in Dutch adults. Randomized pretest-posttest study using a 2 × 2 design. Internet-based. Dutch adults recruited via leaflets and announcements on intranet and Internet and who provided immediate intention (n = 294) and 1-week follow-up intention and fruit intake data (n = 177). Messages combining information on intake of others (low vs high intake) with information about positive or negative outcomes of (in)sufficient fruit intake. Fruit intake intentions and fruit intake. Analyses of covariance. Those already consuming sufficient fruit and receiving negative information about insufficient fruit intake increased their motivation to consume sufficient fruit immediately (P = .03), but not at 1-week follow-up. Those who read positive information about sufficient fruit intake reported higher fruit consumption than those who read negative information about insufficient fruit intake (P = .03). This was stronger in those already consuming sufficient fruit. There were no effects of descriptive norm information (P > .19). Information about outcomes was more persuasive than descriptive majority norm information. Effects were generally stronger in those already consuming sufficient fruit. Copyright © 2015 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

  20. Brain Stimulation Studies of Social Norm Compliance: Implications for Personality Disorders?

    PubMed

    Ruff, Christian C

    2018-01-01

    Several personality disorders involve pathological behaviors that violate social norms, commonly held expectations about what ought to be done in specific situations. These symptoms usually emerge early in development, are persistent and hard to treat, and are often ego-syntonic. Here I present some recent brain stimulation studies suggesting that pathological changes in different aspects of norm-compliant behavior reflect dysfunctions of brain circuits involving distinct prefrontal brain areas. One set of studies shows that transcranial direct current stimulation of the right lateral prefrontal cortex changes the behavioral sensitivity to social incentives for norm-compliant behavior. Crucially, social norm compliance in response to such incentives could even be increased during excitatory stimulation, demonstrating that the affected neural process is a biological prerequisite for appropriate reaction to social signals that trigger norm compliance. In another set of studies, we show that stimulation of a different (more dorsal) part of the right prefrontal cortex enhances honesty in a realistic setting where participants had the opportunity to cheat for real monetary gains. Interestingly, these stimulation-induced increases in both socially cued or purely voluntary norm compliance were not linked to changes in other aspects of decision- making (such as risk or impatience), and they did not reflect changes in beliefs about what is appropriate behavior. These results suggest that disorders of distinct brain circuits may causally underlie egosyntotic changes in norm-compliant behavior. This raises the tantalizing possibility that pathologies of norm-compliant behavior may be ameliorated by interventions targeting the function of these brain circuits. © 2018 S. Karger AG, Basel.