Metabolic engineering of strains: from industrial-scale to lab-scale chemical production.

PubMed

Sun, Jie; Alper, Hal S

2015-03-01

A plethora of successful metabolic engineering case studies have been published over the past several decades. Here, we highlight a collection of microbially produced chemicals using a historical framework, starting with titers ranging from industrial scale (more than 50 g/L), to medium-scale (5-50 g/L), and lab-scale (0-5 g/L). Although engineered Escherichia coli and Saccharomyces cerevisiae emerge as prominent hosts in the literature as a result of well-developed genetic engineering tools, several novel native-producing strains are gaining attention. This review catalogs the current progress of metabolic engineering towards production of compounds such as acids, alcohols, amino acids, natural organic compounds, and others.

Heat transfer analysis of a lab scale solar receiver using the discrete ordinates model

NASA Astrophysics Data System (ADS)

Dordevich, Milorad C. W.

This thesis documents the development, implementation and simulation outcomes of the Discrete Ordinates Radiation Model in ANSYS FLUENT simulating the radiative heat transfer occurring in the San Diego State University lab-scale Small Particle Heat Exchange Receiver. In tandem, it also serves to document how well the Discrete Ordinates Radiation Model results compared with those from the in-house developed Monte Carlo Ray Trace Method in a number of simplified geometries. The secondary goal of this study was the inclusion of new physics, specifically buoyancy. Implementation of an additional Monte Carlo Ray Trace Method software package known as VEGAS, which was specifically developed to model lab scale solar simulators and provide directional, flux and beam spread information for the aperture boundary condition, was also a goal of this study. Upon establishment of the model, test cases were run to understand the predictive capabilities of the model. It was shown that agreement within 15% was obtained against laboratory measurements made in the San Diego State University Combustion and Solar Energy Laboratory with the metrics of comparison being the thermal efficiency and outlet, wall and aperture quartz temperatures. Parametric testing additionally showed that the thermal efficiency of the system was very dependent on the mass flow rate and particle loading. It was also shown that the orientation of the small particle heat exchange receiver was important in attaining optimal efficiency due to the fact that buoyancy induced effects could not be neglected. The analyses presented in this work were all performed on the lab-scale small particle heat exchange receiver. The lab-scale small particle heat exchange receiver is 0.38 m in diameter by 0.51 m tall and operated with an input irradiation flux of 3 kWth and a nominal mass flow rate of 2 g/s with a suspended particle mass loading of 2 g/m3. Finally, based on acumen gained during the implementation and development

Protein in Urine: MedlinePlus Lab Test Information

MedlinePlus

... Lab Tests Online [Internet]. American Association for Clinical Chemistry; c2001–2017. Pre-eclampsia: Overview [updated 2016 Feb ... Tests Online: Urinalysis [Internet]. American Association for Clinical Chemistry; c2001–2017. Urinalysis: The Test [updated 2016 May ...

Construct and test scale model box culvert design project.

DOT National Transportation Integrated Search

2010-11-01

The research team at the University of New Mexicos (UNM) hydraulics lab designed, constructed, and : tested a 1:20 scale physical model of a proposed culvert in Jemez Springs, New Mexico. The culvert : design was developed by the New Mexico Depart...

Comparison between simulations and lab results on the ASSIST test-bench

NASA Astrophysics Data System (ADS)

Le Louarn, Miska; Madec, Pierre-Yves; Kolb, Johann; Paufique, Jerome; Oberti, Sylvain; La Penna, Paolo; Arsenault, Robin

2016-07-01

We present the latest comparison results between laboratory tests carried out on the ASSIST test bench and Octopus end-to end simulations. We simulated, as closely to the lab conditions as possible, the different AOF modes (Maintenance and commissioning mode (SCAO), GRAAL (GLAO in the near IR), Galacsi Wide Field mode (GLAO in the visible) and Galacsi narrow field mode (LTAO in the visible)). We then compared the simulation results to the ones obtained on the lab bench. Several aspects were investigated, like number of corrected modes, turbulence wind speeds, LGS photon flux etc. The agreement between simulations and lab is remarkably good for all investigated parameters, giving great confidence in both simulation tool and performance of the AO system in the lab.

End-effects-regime in full scale and lab scale rocket nozzles

NASA Astrophysics Data System (ADS)

Rojo, Raymundo; Tinney, Charles; Baars, Woutijn; Ruf, Joseph

2014-11-01

Modern rockets utilize a thrust-optimized parabolic-contour design for their nozzles for its high performance and reliability. However, the evolving internal flow structures within these high area ratio rocket nozzles during start up generate a powerful amount of vibro-acoustic loads that act on the launch vehicle. Modern rockets must be designed to accommodate for these heavy loads or else risk a catastrophic failure. This study quantifies a particular moment referred to as the ``end-effects regime,'' or the largest source of vibro-acoustic loading during start-up [Nave & Coffey, AIAA Paper 1973-1284]. Measurements from full scale ignitions are compared with aerodynamically scaled representations in a fully anechoic chamber. Laboratory scale data is then matched with both static and dynamic wall pressure measurements to capture the associating shock structures within the nozzle. The event generated during the ``end-effects regime'' was successfully reproduced in the both the lab-scale models, and was characterized in terms of its mean, variance and skewness, as well as the spectral properties of the signal obtained by way of time-frequency analyses.

Blood in Urine: MedlinePlus Lab Test Information

MedlinePlus

... Information → Blood in Urine URL of this page: https://medlineplus.gov/labtests/bloodinurine.html Blood in Urine ... 2017 Mar 14]; [about 4 screens]: Available from: https://labtestsonline.org/understanding/analytes/urinalysis/tab/test Lab ...

Lab and Pore-Scale Study of Low Permeable Soils Diffusional Tortuosity

NASA Astrophysics Data System (ADS)

Lekhov, V.; Pozdniakov, S. P.; Denisova, L.

2016-12-01

Diffusion plays important role in contaminant spreading in low permeable units. The effective diffusion coefficient of saturated porous medium depends on this coefficient in water, porosity and structural parameter of porous space - tortuosity. Theoretical models of relationship between porosity and diffusional tortuosity are usually derived for conceptual granular models of medium filled by solid particles of simple geometry. These models usually do not represent soils with complex microstructure. The empirical models, like as Archie's law, based on the experimental electrical conductivity data are mostly useful for practical applications. Such models contain empirical parameters that should be defined experimentally for given soil type. In this work, we compared tortuosity values obtained in lab-scale diffusional experiments and pore scale diffusion simulation for the studied soil microstructure and exanimated relationship between tortuosity and porosity. Samples for the study were taken from borehole cores of low-permeable silt-clay formation. Using the samples of 50 cm3 we performed lab scale diffusional experiments and estimated the lab-scale tortuosity. Next using these samples we studied the microstructure with X-ray microtomograph. Shooting performed on undisturbed microsamples of size 1,53 mm with a resolution ×300 (10243 vox). After binarization of each obtained 3-D structure, its spatial correlation analysis was performed. This analysis showed that the spatial correlation scale of the indicator variogram is considerably smaller than microsample length. Then there was the numerical simulation of the Laplace equation with binary coefficients for each microsamples. The total number of simulations at the finite-difference grid of 1753 cells was 3500. As a result the effective diffusion coefficient, tortuosity and porosity values were obtained for all studied microsamples. The results were analyzed in the form of graph of tortuosity versus porosity. The 6

The Immersive Virtual Reality Lab: Possibilities for Remote Experimental Manipulations of Autonomic Activity on a Large Scale.

PubMed

Juvrud, Joshua; Gredebäck, Gustaf; Åhs, Fredrik; Lerin, Nils; Nyström, Pär; Kastrati, Granit; Rosén, Jörgen

2018-01-01

There is a need for large-scale remote data collection in a controlled environment, and the in-home availability of virtual reality (VR) and the commercial availability of eye tracking for VR present unique and exciting opportunities for researchers. We propose and provide a proof-of-concept assessment of a robust system for large-scale in-home testing using consumer products that combines psychophysiological measures and VR, here referred to as a Virtual Lab. For the first time, this method is validated by correlating autonomic responses, skin conductance response (SCR), and pupillary dilation, in response to a spider, a beetle, and a ball using commercially available VR. Participants demonstrated greater SCR and pupillary responses to the spider, and the effect was dependent on the proximity of the stimuli to the participant, with a stronger response when the spider was close to the virtual self. We replicated these effects across two experiments and in separate physical room contexts to mimic variability in home environment. Together, these findings demonstrate the utility of pupil dilation as a marker of autonomic arousal and the feasibility to assess this in commercially available VR hardware and support a robust Virtual Lab tool for massive remote testing.

The Immersive Virtual Reality Lab: Possibilities for Remote Experimental Manipulations of Autonomic Activity on a Large Scale

PubMed Central

Juvrud, Joshua; Gredebäck, Gustaf; Åhs, Fredrik; Lerin, Nils; Nyström, Pär; Kastrati, Granit; Rosén, Jörgen

2018-01-01

There is a need for large-scale remote data collection in a controlled environment, and the in-home availability of virtual reality (VR) and the commercial availability of eye tracking for VR present unique and exciting opportunities for researchers. We propose and provide a proof-of-concept assessment of a robust system for large-scale in-home testing using consumer products that combines psychophysiological measures and VR, here referred to as a Virtual Lab. For the first time, this method is validated by correlating autonomic responses, skin conductance response (SCR), and pupillary dilation, in response to a spider, a beetle, and a ball using commercially available VR. Participants demonstrated greater SCR and pupillary responses to the spider, and the effect was dependent on the proximity of the stimuli to the participant, with a stronger response when the spider was close to the virtual self. We replicated these effects across two experiments and in separate physical room contexts to mimic variability in home environment. Together, these findings demonstrate the utility of pupil dilation as a marker of autonomic arousal and the feasibility to assess this in commercially available VR hardware and support a robust Virtual Lab tool for massive remote testing. PMID:29867318

GeoLab 2011: New Instruments and Operations Tested at Desert RATS

NASA Technical Reports Server (NTRS)

Evans, Cindy A.; Calaway, M. J.; Bell, M. S.

2012-01-01

GeoLab is a geological laboratory and testbed designed for supporting geoscience activities during NASA's analog demonstrations. Scientists at NASA's Johnson Space Center built GeoLab as part of a technology project to aid the development of science operational concepts for future planetary surface missions [1, 2, 3]. It is integrated into NASA's Habitat Demonstration Unit, a first generation exploration habitat test article. As a prototype workstation, GeoLab provides a high fidelity working space for analog mission crewmembers to perform in-situ characterization of geologic samples and communicate their findings with supporting scientists. GeoLab analog operations can provide valuable data for assessing the operational and scientific considerations of surface-based geologic analyses such as preliminary examination of samples collected by astronaut crews [4, 5]. Our analog tests also feed into sample handling and advanced curation operational concepts and procedures that will, ultimately, help ensure that the most critical samples are collected during future exploration on a planetary surface, and aid decisions about sample prioritization, sample handling and return. Data from GeoLab operations also supports science planning during a mission by providing additional detailed geologic information to supporting scientists, helping them make informed decisions about strategies for subsequent sample collection opportunities.

RANS Simulation (Virtual Blade Model [VBM]) of Single Lab Scaled DOE RM1 MHK Turbine

DOE Data Explorer

Javaherchi, Teymour; Stelzenmuller, Nick; Aliseda, Alberto; Seydel, Joseph

2014-04-15

Attached are the .cas and .dat files for the Reynolds Averaged Navier-Stokes (RANS) simulation of a single lab-scaled DOE RM1 turbine implemented in ANSYS FLUENT CFD-package. The lab-scaled DOE RM1 is a re-design geometry, based of the full scale DOE RM1 design, producing same power output as the full scale model, while operating at matched Tip Speed Ratio values at reachable laboratory Reynolds number (see attached paper). In this case study the flow field around and in the wake of the lab-scaled DOE RM1 turbine is simulated using Blade Element Model (a.k.a Virtual Blade Model) by solving RANS equations coupled with k-\\omega turbulence closure model. It should be highlighted that in this simulation the actual geometry of the rotor blade is not modeled. The effect of turbine rotating blades are modeled using the Blade Element Theory. This simulation provides an accurate estimate for the performance of device and structure of it's turbulent far wake. Due to the simplifications implemented for modeling the rotating blades in this model, VBM is limited to capture details of the flow field in near wake region of the device. The required User Defined Functions (UDFs) and look-up table of lift and drag coefficients are included along with the .cas and .dat files.

Evaluation of direct-to-consumer low-volume lab tests in healthy adults.

PubMed

Kidd, Brian A; Hoffman, Gabriel; Zimmerman, Noah; Li, Li; Morgan, Joseph W; Glowe, Patricia K; Botwin, Gregory J; Parekh, Samir; Babic, Nikolina; Doust, Matthew W; Stock, Gregory B; Schadt, Eric E; Dudley, Joel T

2016-05-02

Clinical laboratory tests are now being prescribed and made directly available to consumers through retail outlets in the USA. Concerns with these test have been raised regarding the uncertainty of testing methods used in these venues and a lack of open, scientific validation of the technical accuracy and clinical equivalency of results obtained through these services. We conducted a cohort study of 60 healthy adults to compare the uncertainty and accuracy in 22 common clinical lab tests between one company offering blood tests obtained from finger prick (Theranos) and 2 major clinical testing services that require standard venipuncture draws (Quest and LabCorp). Samples were collected in Phoenix, Arizona, at an ambulatory clinic and at retail outlets with point-of-care services. Theranos flagged tests outside their normal range 1.6× more often than other testing services (P < 0.0001). Of the 22 lab measurements evaluated, 15 (68%) showed significant interservice variability (P < 0.002). We found nonequivalent lipid panel test results between Theranos and other clinical services. Variability in testing services, sample collection times, and subjects markedly influenced lab results. While laboratory practice standards exist to control this variability, the disparities between testing services we observed could potentially alter clinical interpretation and health care utilization. Greater transparency and evaluation of testing technologies would increase their utility in personalized health management. This work was supported by the Icahn Institute for Genomics and Multiscale Biology, a gift from the Harris Family Charitable Foundation (to J.T. Dudley), and grants from the NIH (R01 DK098242 and U54 CA189201, to J.T. Dudley, and R01 AG046170 and U01 AI111598, to E.E. Schadt).

RANS Simulation (Rotating Reference Frame Model [RRF]) of Single Lab-Scaled DOE RM1 MHK Turbine

DOE Data Explorer

Javaherchi, Teymour; Stelzenmuller, Nick; Aliseda, Alberto; Seydel, Joseph

2014-04-15

Attached are the .cas and .dat files for the Reynolds Averaged Navier-Stokes (RANS) simulation of a single lab-scaled DOE RM1 turbine implemented in ANSYS FLUENT CFD-package. The lab-scaled DOE RM1 is a re-design geometry, based of the full scale DOE RM1 design, producing same power output as the full scale model, while operating at matched Tip Speed Ratio values at reachable laboratory Reynolds number (see attached paper). In this case study taking advantage of the symmetry of lab-scaled DOE RM1 geometry, only half of the geometry is models using (Single) Rotating Reference Frame model [RRF]. In this model RANS equations, coupled with k-\\omega turbulence closure model, are solved in the rotating reference frame. The actual geometry of the turbine blade is included and the turbulent boundary layer along the blade span is simulated using wall-function approach. The rotation of the blade is modeled by applying periodic boundary condition to sets of plane of symmetry. This case study simulates the performance and flow field in the near and far wake of the device at the desired operating conditions. The results of these simulations were validated against in-house experimental data. Please see the attached paper.

Assessing the changes in E. coli levels and nutrient dynamics during vermicomposting of food waste under lab and field scale conditions.

PubMed

Cao, Wenlong; Vaddella, Venkata; Biswas, Sagor; Perkins, Katherine; Clay, Cameron; Wu, Tong; Zheng, Yawen; Ndegwa, Pius; Pandey, Pramod

2016-11-01

Vermicomposting (VC) has proven to be a promising method for treating garden, household, and municipal wastes. Although the VC has been used extensively for converting wastes into fertilizers, pathogens such as Escherichia coli (E. coli) survival during this process is not well documented. In this study, both lab and field scale experiments were conducted assessing the impacts of earthworms in reducing E. coli concentration during VC of food waste. In addition, other pertinent parameters such as temperature, carbon and nitrogen content, moisture content, pH, volatile solids, micronutrients (P, K, Ca, Mg, and S), and heavy metals (Zn, Mn, Fe, and Cu) were monitored during the study. The lab and field scale experiments were conducted for 107 and 103 days, respectively. The carbon to nitrogen ratio (C/N) decreased by 54 % in the lab scale study and by 36 % in the field study. Results showed that VC was not significantly effective in reducing E. coli levels in food waste under both lab and field scale settings. The carbon to nitrogen ratio (C/N) decreased by 54 % in the lab scale study and by 36 % in the field study.

Evaluation of direct-to-consumer low-volume lab tests in healthy adults

PubMed Central

Kidd, Brian A.; Hoffman, Gabriel; Zimmerman, Noah; Li, Li; Morgan, Joseph W.; Glowe, Patricia K.; Botwin, Gregory J.; Parekh, Samir; Babic, Nikolina; Doust, Matthew W.; Stock, Gregory B.; Schadt, Eric E.; Dudley, Joel T.

2016-01-01

BACKGROUND. Clinical laboratory tests are now being prescribed and made directly available to consumers through retail outlets in the USA. Concerns with these test have been raised regarding the uncertainty of testing methods used in these venues and a lack of open, scientific validation of the technical accuracy and clinical equivalency of results obtained through these services. METHODS. We conducted a cohort study of 60 healthy adults to compare the uncertainty and accuracy in 22 common clinical lab tests between one company offering blood tests obtained from finger prick (Theranos) and 2 major clinical testing services that require standard venipuncture draws (Quest and LabCorp). Samples were collected in Phoenix, Arizona, at an ambulatory clinic and at retail outlets with point-of-care services. RESULTS. Theranos flagged tests outside their normal range 1.6× more often than other testing services (P < 0.0001). Of the 22 lab measurements evaluated, 15 (68%) showed significant interservice variability (P < 0.002). We found nonequivalent lipid panel test results between Theranos and other clinical services. Variability in testing services, sample collection times, and subjects markedly influenced lab results. CONCLUSION. While laboratory practice standards exist to control this variability, the disparities between testing services we observed could potentially alter clinical interpretation and health care utilization. Greater transparency and evaluation of testing technologies would increase their utility in personalized health management. FUNDING. This work was supported by the Icahn Institute for Genomics and Multiscale Biology, a gift from the Harris Family Charitable Foundation (to J.T. Dudley), and grants from the NIH (R01 DK098242 and U54 CA189201, to J.T. Dudley, and R01 AG046170 and U01 AI111598, to E.E. Schadt). PMID:27018593

Application of lab derived kinetic biodegradation parameters at the field scale

NASA Astrophysics Data System (ADS)

Schirmer, M.; Barker, J. F.; Butler, B. J.; Frind, E. O.

2003-04-01

Estimating the intrinsic remediation potential of an aquifer typically requires the accurate assessment of the biodegradation kinetics, the level of available electron acceptors and the flow field. Zero- and first-order degradation rates derived at the laboratory scale generally overpredict the rate of biodegradation when applied to the field scale, because limited electron acceptor availability and microbial growth are typically not considered. On the other hand, field estimated zero- and first-order rates are often not suitable to forecast plume development because they may be an oversimplification of the processes at the field scale and ignore several key processes, phenomena and characteristics of the aquifer. This study uses the numerical model BIO3D to link the laboratory and field scale by applying laboratory derived Monod kinetic degradation parameters to simulate a dissolved gasoline field experiment at Canadian Forces Base (CFB) Borden. All additional input parameters were derived from laboratory and field measurements or taken from the literature. The simulated results match the experimental results reasonably well without having to calibrate the model. An extensive sensitivity analysis was performed to estimate the influence of the most uncertain input parameters and to define the key controlling factors at the field scale. It is shown that the most uncertain input parameters have only a minor influence on the simulation results. Furthermore it is shown that the flow field, the amount of electron acceptor (oxygen) available and the Monod kinetic parameters have a significant influence on the simulated results. Under the field conditions modelled and the assumptions made for the simulations, it can be concluded that laboratory derived Monod kinetic parameters can adequately describe field scale degradation processes, if all controlling factors are incorporated in the field scale modelling that are not necessarily observed at the lab scale. In this way

Looking North into Lab Metallurgy Testing Area and Enrichment Motor ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Looking North into Lab Metallurgy Testing Area and Enrichment Motor within Recycle Recovery Building - Hematite Fuel Fabrication Facility, Recycle Recovery Building, 3300 State Road P, Festus, Jefferson County, MO

Recirculation of reverse osmosis concentrate in lab-scale anaerobic and aerobic landfill simulation reactors.

PubMed

Morello, Luca; Cossu, Raffaello; Raga, Roberto; Pivato, Alberto; Lavagnolo, Maria Cristina

2016-10-01

Leachate treatment is a major issue in the context of landfill management, particularly in view of the consistent changes manifested over time in the quality and quantity of leachate produced, linked to both waste and landfill characteristics, which renders the procedure technically difficult and expensive. Leachate recirculation may afford a series of potential advantages, including improvement of leachate quality, enhancement of gas production, acceleration of biochemical processes, control of moisture content, as well as nutrients and microbe migration within the landfill. Recirculation of the products of leachate treatment, such as reverse osmosis (RO) concentrate, is a less common practice, with widespread controversy relating to its suitability, potential impacts on landfill management and future gaseous and leachable emissions. Scientific literature provides the results of only a few full-scale applications of concentrate recirculation. In some cases, an increase of COD and ammonium nitrogen in leachate was observed, coupled with an increase of salinity; which, additionally, might negatively affect performance of the RO plant itself. In other cases, not only did leachate production not increase significantly but the characteristics of leachate extracted from the well closest to the re-injection point also remained unchanged. This paper presents the results of lab-scale tests conducted in landfill simulation reactors, in which the effects of injection of municipal solid waste (MSW) landfill leachate RO concentrate were evaluated. Six reactors were managed with different weekly concentrate inputs, under both anaerobic and aerobic conditions, with the aim of investigating the short and long-term effects of this practice on landfill emissions. Lab-scale tests resulted in a more reliable identification of compound accumulation and kinetic changes than full-scale applications, further enhancing the development of a mass balance in which gaseous emissions and waste

Commerce Lab - An enabling facility and test bed for commercial flight opportunities

NASA Technical Reports Server (NTRS)

Robertson, Jack; Atkins, Harry L.; Williams, John R.

1986-01-01

Commerce Lab is conceived as an adjunct to the National Space Transportation System (NSTS) by providing a focal point for commercial missions which could utilize existing NSTS carrier and resource capabilities for on-orbit experimentation in the microgravity sciences. In this context, the Commerce Lab provides an enabling facility and test bed for commercial flight opportunities. Commerce Lab program activities to date have focused on mission planning for private sector involvement in the space program to facilitate the commercial exploitation of the microgravity environment for materials processing research and development. It is expected that Commerce Lab will provide a logical transition between currently planned NSTS missions and future microgravity science and commercial R&D missions centered around the Space Station. The present study identifies candidate Commerce Lab flight experiments and their development status and projects a mission traffic model that can be used in commercial mission planning.

Transport of pesticides and artificial tracers in vertical-flow lab-scale wetlands

NASA Astrophysics Data System (ADS)

Durst, Romy; Imfeld, Gwenaël.; Lange, Jens

2013-01-01

Wetland systems can be hydrologically connected to a shallow aquifer and intercept upward flow of pesticide-contaminated water during groundwater discharge. However, pesticide transport and attenuation through wetland sediments (WSs) intercepting contaminated water is rarely evaluated quantitatively. The use of artificial tracers to evaluate pesticide transport and associated risks is a fairly new approach that requires evaluation and validation. Here we evaluate during 84 days the transport of two pesticides (i.e., isoproturon (IPU) and metalaxyl (MTX)) and three tracers (i.e., bromide (Br), uranine (UR), and sulforhodamine B (SRB)) in upward vertical-flow vegetated and nonvegetated lab-scale wetlands. The lab-scale wetlands were filled with outdoor WSs and were continuously supplied with tracers and the pesticide-contaminated water. The transport of IPU and UR was characterized by high solute recovery (approximately 80%) and low retardation compared to Br. The detection of desmethylisoproturon in the wetlands indicated IPU degradation. SRB showed larger retardation (>3) and lower recovery (approximately 60%) compared to Br, indicating that sorption controlled SRB transport. MTX was moderately retarded (approximately 1.5), and its load attenuation in the wetland reached 40%. In the vegetated wetland, preferential flow along the roots decreased interactions between solutes and sediments, resulting in larger pesticide and tracer recovery. Our results show that UR and IPU have similar transport characteristics under the tested subsurface-flow conditions, whereas SRB may serve as a proxy for less mobile and more persistent pesticides. Since UR and SRB are not significantly affected by degradation, their use as proxies for fast degrading pollutants may be limited. We anticipate our results to be a starting point for considering artificial tracers for investigating pesticide transport in environments at groundwater/surface-water interfaces.

Methane oxidation and attenuation of sulphur compounds in landfill top cover systems: Lab-scale tests.

PubMed

Raga, Roberto; Pivato, Alberto; Lavagnolo, Maria Cristina; Megido, Laura; Cossu, Raffaello

2018-03-01

In this study, a top cover system is investigated as a control for emissions during the aftercare of new landfills and for old landfills where biogas energy production might not be profitable. Different materials were studied as landfill cover system in lab-scale columns: mechanical-biological pretreated municipal solid waste (MBP); mechanical-biological pretreated biowaste (PB); fine (PBS f ) and coarse (PBS c ) mechanical-biological pretreated mixtures of biowaste and sewage sludge, and natural soil (NS). The effectiveness of these materials in removing methane and sulphur compounds from a gas stream was tested, even coupled with activated carbon membranes. Concentrations of CO 2 , CH 4 , O 2 , N 2 , H 2 S and mercaptans were analysed at different depths along the columns. Methane degradation was assessed using mass balance and the results were expressed in terms of methane oxidation rate (MOR). The highest maximum and mean MOR were observed for MBP (17.2gCH 4 /m 2 /hr and 10.3gCH 4 /m 2 /hr, respectively). Similar values were obtained with PB and PBS c . The lowest values of MOR were obtained for NS (6.7gCH 4 /m 2 /hr) and PBS f (3.6gCH 4 /m 2 /hr), which may be due to their low organic content and void index, respectively. Activated membranes with high load capacity did not seem to have an influence on the methane oxidation process: MBP coupled with 220g/m 2 and 360g/m 2 membranes gave maximum MOR of 16.5gCH 4 /m 2 /hr and 17.4gCH 4 /m 2 /hr, respectively. Activated carbon membranes proved to be very effective on H 2 S adsorption. Furthermore, carbonyl sulphide, ethyl mercaptan and isopropyl mercaptan seemed to be easily absorbed by the filling materials. Copyright © 2017. Published by Elsevier B.V.

InstantLabs Listeria species food safety kit. Performance tested methods 041304.

PubMed

Sharma, Neil; Bambusch, Lauren; Le, Thu; Morey, Amit

2014-01-01

The InstantLabs Listeria Species Food SafetyKitwas validated against the International Organization for Standardization (ISO) reference method 11290-1 for the detection of Listeria monocytogenes and other Listeria species. The matrixes (stainless steel, sealed concrete, cheddar cheese, raw shrimp, and hot dogs) were inoculated with approximately 1 CFU/test portion of various Listeria species to generate fractional positives (5-15) in 20 inoculated samples. Enrichments were also fractionally inoculated with L. monocytogenes for side-by-side testing of the InstantLabs Listeria monocytogenes Food Safety Kit. Stainless steel and sealed concrete samples were validated using 4 x 4" and 1 x 1" test areas, respectively, and enriched in Buffered Listeria Enrichment Broth (BLEB) at 35 +/- 1 degrees C for 22-28 h. All food samples were tested at 25 g or 25 mL and enriched in BLEB at 35 +/- 1 degrees C for 24-28 h. All samples were confirmed using the ISO reference method, regardless of initial screen result. The InstantLabs test method performed as well as or better than the reference method for the detection of Listeria species on stainless steel, sealed concrete, cheddar cheese, raw shrimp, and hot dogs. Inclusivity and exclusivity testing revealed no false negatives and no false positives among the 80 Listeria species and 30 non-Listeria species examined. The method was shown to be robust when variations were introduced to the enrichment time, the volume for DNA extraction, and the heat block time (data not shown).

Assessment of the human epidermal model LabCyte EPI-MODEL for In vitro skin corrosion testing according to the OECD test guideline 431.

PubMed

Katoh, Masakazu; Hamajima, Fumiyasu; Ogasawara, Takahiro; Hata, Ken-Ichiro

2010-06-01

A new OECD test guideline 431 (TG431) for in vitro skin corrosion tests using human reconstructed skin models was adopted by OECD in 2004. TG431 defines the criteria for the general function and performance of applicable skin models. In order to confirm that the new reconstructed human epidermal model, LabCyte EPI-MODEL is applicable for the skin corrosion test according to TG431, the predictability and repeatability of the model for the skin corrosion test was evaluated. The test was performed according to the test protocol described in TG431. Based on the knowledge that LabCyte EPI-MODEL is an epidermal model as well as EpiDerm, we decided to adopt the the Epiderm prediction model of skin corrosion for the LabCyte EPI-MODEL, using twenty test chemicals (10 corrosive chemicals and 10 non-corrosive chemicals) in the 1(st) stage. The prediction model results showed that the distinction of non-corrosion to corrosion corresponded perfectly. Therefore, it was judged that the prediction model of EpiDerm could be applied to the LabCyte EPI-MODEL. In the 2(nd) stage, the repeatability of this test protocol with the LabCyte EPI-MODEL was examined using twelve chemicals (6 corrosive chemicals and 6 non-corrosive chemicals) that are described in TG431, and these results recognized a high repeatability and accurate predictability. It was concluded that LabCyte EPI-MODEL is applicable for the skin corrosive test protocol according to TG431.

Transfer of tracers and pesticides in lab scale wetland systems: the role of vegetation

NASA Astrophysics Data System (ADS)

Durst, R.; Imfeld, G.; Lange, J.

2012-04-01

Surface wetlands can collect contaminated runoff from urban or agricultural catchments and have intrinsic physical, chemical and biological retention and removal processes useful for mitigating contaminants, including pesticides, and thus limiting the contamination of aquatic ecosystems. Yet little is known about the transfer of pesticides between wetlands collecting pesticides runoff and groundwater, and the subsequent threat of groundwater contamination. In particular, the influence of wetland vegetation and related processes during pesticide transfer is largely unknown. Here we evaluate the transfer of the widely used herbicide Isoproturon (IPU) and the fungicide Metalaxyl (MTX) with that of Uranine (UR) and Sulphorhodamine (SRB) in a vegetated and a non-vegetated lab-scale wetland. UR and SRB had successfully served as a reference for pesticides in surface wetlands. We filled two 65 cm long and 15 cm diameter borosilicate columns with sediment cores from a wetland, one without and one with vegetation (Phragmites australis, Cav.). When a constant flow-through rate of 0.33 ml min-1 was reached, tracers and pesticides were injected simultaneously and continuously. The hydrological mass balance and tracer concentrations were measured daily at the outlet of the lab-scale wetland. Samples for pesticides and hydrochemical analyses were collected biweekly. The lab-scale wetlands were covered to limit evaporation and light decay of injected compounds. The reactive transfer of compounds in the vegetated and non-vegetated lab-scale wetland was compared based on breakthrough curves (BTC's) and model parameters of the lumped parameter model CXTFIT. The hydrologic balance revealed that the intensity of transpiration and hence plant activity in the lab-scale wetlands progressively decreased and then apparently ceased after about eight days following continuous pesticide injection. In this first phase, no significant difference in the hydrologic balances could be observed

DETAIL VIEW OF TESTING EQUIPMENT, REMOTE MANIPULATOR SYSTEM LAB, ROOM ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

DETAIL VIEW OF TESTING EQUIPMENT, REMOTE MANIPULATOR SYSTEM LAB, ROOM NO. 1N4, FACING SOUTHEAST - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

Comparison of lab, pilot, and industrial scale low consistency mechanical refining for improvements in enzymatic digestibility of pretreated hardwood.

PubMed

Jones, Brandon W; Venditti, Richard; Park, Sunkyu; Jameel, Hasan

2014-09-01

Mechanical refining has been shown to improve biomass enzymatic digestibility. In this study industrial high-yield sodium carbonate hardwood pulp was subjected to lab, pilot and industrial refining to determine if the mechanical refining improves the enzymatic hydrolysis sugar conversion efficiency differently at different refining scales. Lab, pilot and industrial refining increased the biomass digestibility for lignocellulosic biomass relative to the unrefined material. The sugar conversion was increased from 36% to 65% at 5 FPU/g of biomass with industrial refining at 67.0 kWh/t, which was more energy efficient than lab and pilot scale refining. There is a maximum in the sugar conversion with respect to the amount of refining energy. Water retention value is a good predictor of improvements in sugar conversion for a given fiber source and composition. Improvements in biomass digestibility with refining due to lab, pilot plant and industrial refining were similar with respect to water retention value. Published by Elsevier Ltd.

LPT. Shield test facility (TAN645 and 646). Calibration lab shield ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

LPT. Shield test facility (TAN-645 and -646). Calibration lab shield door. Ralph M. Parsons 1229-17 ANP/GE-6-645-MS-1. April 1957. Approved by INEEL Classification Office for public release. INEEL index code no. 037-0645-40-693-107369 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

Kedalion: NASA's Adaptable and Agile Hardware/Software Integration and Test Lab

NASA Technical Reports Server (NTRS)

Mangieri, Mark L.; Vice, Jason

2011-01-01

NASA fs Kedalion engineering analysis lab at Johnson Space Center is on the forefront of validating and using many contemporary avionics hardware/software development and integration techniques, which represent new paradigms to heritage NASA culture. Kedalion has validated many of the Orion hardware/software engineering techniques borrowed from the adjacent commercial aircraft avionics solution space, with the intention to build upon such techniques to better align with today fs aerospace market. Using agile techniques, commercial products, early rapid prototyping, in-house expertise and tools, and customer collaboration, Kedalion has demonstrated that cost effective contemporary paradigms hold the promise to serve future NASA endeavors within a diverse range of system domains. Kedalion provides a readily adaptable solution for medium/large scale integration projects. The Kedalion lab is currently serving as an in-line resource for the project and the Multipurpose Crew Vehicle (MPCV) program.

Visualization of lunar excavation test in NASA Glenn's GRUVE Lab

NASA Image and Video Library

1969-12-31

Calvin Robinson of NASA Glenn's GVIS Team demonstrates a visualization of an excavation test conducted at NASA Glenn Research Center's SLOPE Lab ( https://rt.grc.nasa.gov/main/rlc/simu... ) . The visualization shows the flow of a lunar soil simulant as it flows in and past a proposed excavation bucket.

Plasma Physics Lab and the Tokamak Fusion Test Reactor, 1989

ScienceCinema

None

2018-01-16

From the Princeton University Archives: Promotional video about the Plasma Physics Lab and the new Tokamak Fusion Test Reactor (TFTR), with footage of the interior, machines, and scientists at work. This film is discussed in the audiovisual blog of the Seeley G. Mudd Manuscript Library, which holds the archives of Princeton University.

The U.S. Lab placed in vacuum chamber for leak test

NASA Technical Reports Server (NTRS)

2000-01-01

In the Operations and Checkout Building, the U.S. Lab, a component of the International Space Station, is lowered into a three-story vacuum chamber. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research.

Model-based strategy for cell culture seed train layout verified at lab scale.

PubMed

Kern, Simon; Platas-Barradas, Oscar; Pörtner, Ralf; Frahm, Björn

2016-08-01

Cell culture seed trains-the generation of a sufficient viable cell number for the inoculation of the production scale bioreactor, starting from incubator scale-are time- and cost-intensive. Accordingly, a seed train offers potential for optimization regarding its layout and the corresponding proceedings. A tool has been developed to determine the optimal points in time for cell passaging from one scale into the next and it has been applied to two different cell lines at lab scale, AGE1.HN AAT and CHO-K1. For evaluation, experimental seed train realization has been evaluated in comparison to its layout. In case of the AGE1.HN AAT cell line, the results have also been compared to the formerly manually designed seed train. The tool provides the same seed train layout based on the data of only two batches.

A survey of Lab Tests Online-UK users: a key resource for patients to empower and help them understand their laboratory test results.

PubMed

Leyland, Rebecca; Freedman, Danielle B

2016-11-01

Background Lab Tests Online-UK celebrated its 10th anniversary in 2014 and to mark the occasion the first comprehensive survey of website users was undertaken. Methods A pop-up box with a link to Survey Monkey was used to offer website users the chance to participate in the survey, which was live from 4 March 2014 to 11 April 2014. Results Six hundred and sixty-one participants started the questionnaire and 338 completed all of the demographic questions. Although the website is designed and aimed at patients and the public, a significant number of respondents were health-care professionals (47%). The majority of survey participants found the Lab Tests Online-UK website via a search engine and were visiting the site for themselves. The majority of participants found what they were looking for on the website and found the information very easy or fairly easy to understand. The patient respondents were keen to see their laboratory test results (87%), but the majority did not have access (60%) at the time of the survey. Conclusions This survey provides good evidence that the Lab Tests Online-UK website is a useful resource for patients and health-care professionals alike. It comes at a poignant time as the release of results direct to patients starts with access to their medical records. The Lab Tests Online-UK website has a key role in enabling patients to understand their lab test results, and therefore empowering them to take an interest and engage in their own healthcare.

The U.S. Lab is placed in vacuum chamber for leak test

NASA Technical Reports Server (NTRS)

2000-01-01

With the lid of the three-story vacuum chamber in place, a worker on top checks release of the cables. Inside the chamber is the U.S. Lab, a component of the International Space Station. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research.

The U.S. Lab is placed in vacuum chamber for leak test

NASA Technical Reports Server (NTRS)

2000-01-01

A worker in the Operations and Checkout Building checks the placement of the lid on the vacuum chamber containing the U.S. Lab, a component of the International Space Station. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research.

The U.S. Lab is placed in vacuum chamber for leak test

NASA Technical Reports Server (NTRS)

2000-01-01

Workers in the Operations and Checkout Building check the placement of the lid on the vacuum chamber containing the U.S. Lab, a component of the International Space Station. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research.

Lab-scaled model to evaluate odor and gas production from cattle confinement facilities with deep bedded packs

USDA-ARS?s Scientific Manuscript database

A lab-scaled simulated bedded pack model was developed to study air quality and nutrient composition of deep-bedded packs found in cattle monoslope facilities. This protocol has been used to effectively evaluate many different bedding materials, environmental variables (temperature, humidity), and ...

RANS Simulation (Virtual Blade Model [VBM]) of Array of Three Coaxial Lab Scaled DOE RM1 MHK Turbine with 5D Spacing

DOE Data Explorer

Javaherchi, Teymour

2016-06-08

Attached are the .cas and .dat files along with the required User Defined Functions (UDFs) and look-up table of lift and drag coefficients for the Reynolds Averaged Navier-Stokes (RANS) simulation of three coaxially located lab-scaled DOE RM1 turbine implemented in ANSYS FLUENT CFD-package. The lab-scaled DOE RM1 is a re-design geometry, based of the full scale DOE RM1 design, producing same power output as the full scale model, while operating at matched Tip Speed Ratio values at reachable laboratory Reynolds number (see attached paper). In this case study the flow field around and in the wake of the lab-scaled DOE RM1 turbines in a coaxial array is simulated using Blade Element Model (a.k.a Virtual Blade Model) by solving RANS equations coupled with k-\\omega turbulence closure model. It should be highlighted that in this simulation the actual geometry of the rotor blade is not modeled. The effect of turbine rotating blades are modeled using the Blade Element Theory. This simulation provides an accurate estimate for the performance of each device and structure of their turbulent far wake. The results of these simulations were validated against the developed in-house experimental data. Simulations for other turbine configurations are available upon request.

MethLAB

PubMed Central

Kilaru, Varun; Barfield, Richard T; Schroeder, James W; Smith, Alicia K

2012-01-01

Recent evidence suggests that DNA methylation changes may underlie numerous complex traits and diseases. The advent of commercial, array-based methods to interrogate DNA methylation has led to a profusion of epigenetic studies in the literature. Array-based methods, such as the popular Illumina GoldenGate and Infinium platforms, estimate the proportion of DNA methylated at single-base resolution for thousands of CpG sites across the genome. These arrays generate enormous amounts of data, but few software resources exist for efficient and flexible analysis of these data. We developed a software package called MethLAB (http://genetics.emory.edu/conneely/MethLAB) using R, an open source statistical language that can be edited to suit the needs of the user. MethLAB features a graphical user interface (GUI) with a menu-driven format designed to efficiently read in and manipulate array-based methylation data in a user-friendly manner. MethLAB tests for association between methylation and relevant phenotypes by fitting a separate linear model for each CpG site. These models can incorporate both continuous and categorical phenotypes and covariates, as well as fixed or random batch or chip effects. MethLAB accounts for multiple testing by controlling the false discovery rate (FDR) at a user-specified level. Standard output includes a spreadsheet-ready text file and an array of publication-quality figures. Considering the growing interest in and availability of DNA methylation data, there is a great need for user-friendly open source analytical tools. With MethLAB, we present a timely resource that will allow users with no programming experience to implement flexible and powerful analyses of DNA methylation data. PMID:22430798

Generalized Nanosatellite Avionics Testbed Lab

NASA Technical Reports Server (NTRS)

Frost, Chad R.; Sorgenfrei, Matthew C.; Nehrenz, Matt

2015-01-01

The Generalized Nanosatellite Avionics Testbed (G-NAT) lab at NASA Ames Research Center provides a flexible, easily accessible platform for developing hardware and software for advanced small spacecraft. A collaboration between the Mission Design Division and the Intelligent Systems Division, the objective of the lab is to provide testing data and general test protocols for advanced sensors, actuators, and processors for CubeSat-class spacecraft. By developing test schemes for advanced components outside of the standard mission lifecycle, the lab is able to help reduce the risk carried by advanced nanosatellite or CubeSat missions. Such missions are often allocated very little time for testing, and too often the test facilities must be custom-built for the needs of the mission at hand. The G-NAT lab helps to eliminate these problems by providing an existing suite of testbeds that combines easily accessible, commercial-offthe- shelf (COTS) processors with a collection of existing sensors and actuators.

Leaching behaviour of different scrap materials at recovery and recycling companies: full-, pilot- and lab-scale investigation.

PubMed

Blondeel, E; Chys, M; Depuydt, V; Folens, K; Du Laing, G; Verliefde, A; Van Hulle, S W H

2014-12-01

Scrap material recovery and recycling companies are confronted with waste water that has a highly fluctuating flow rate and composition. Common pollutants, such as COD, nutrients and suspended solids, potentially toxic metals, polyaromatic hydrocarbons and poly chlorinated biphenyls can exceed the discharge limits. An analysis of the leaching behaviour of different scrap materials and scrap yard sweepings was performed at full-scale, pilot-scale and lab-scale in order to find possible preventive solutions for this waste water problem. The results of these leaching tests (with concentrations that frequently exceeded the Flemish discharge limits) showed the importance of regular sweeping campaigns at the company, leak proof or covered storage of specific scrap materials and oil/water separation on particular leachates. The particulate versus dissolved fraction was also studied for the pollutants. For example, up to 98% of the polyaromatic hydrocarbons, poly chlorinated biphenyls and some metals were in the particulate form. This confirms the (potential) applicability of sedimentation and filtration techniques for the treatment of the majority of the leachates, and as such the rainwater run-off as a whole. Copyright © 2014 Elsevier Ltd. All rights reserved.

InstantLabs Listeria monocytogenes food safety kit. Performance tested method 051304.

PubMed

Sharma, Neil; Bambusch, Lauren; Le, Thu; Morey, Amit

2014-01-01

The InstantLabs Listeria monocytogenes Food Safety Kit was validated against the International Organization for Standardization (ISO) reference method 11290-1 for the detection of Listeria monocytogenes and other Listeria species. The matrixes (stainless steel, sealed concrete, ice cream, whole milk, cheddar cheese, raw shrimp, hot dogs, deli turkey, and lettuce) were inoculated with approximately 1 CFU/test portion of L. monocytogenes to generate fractional positives (5-15) in 20 inoculated samples. Enrichments were also fractionally inoculated with L. grayii for side-by-side testing of the Listeria Species Food Safety Kit. Stainless steel and sealed concrete samples were validated using 4 x 4" and 1 x 1 " test areas, respectively, and enriched in Buffered Listeria Enrichment Broth (BLEB) at 35 +/- 1degreesC for 22-28 h. All food samples were tested at 25 g and enriched in BLEB at 35 +/- 1 degreesC for 24-28 h. All samples were confirmed using the ISO reference method, regardless of initial screen result. The InstantLabs test method performed as well as or better than the reference method for the detection of L. monocytogenes on stainless steel and sealed concrete and in ice cream, whole milk, cheddar cheese, raw shrimp, hot dogs, deli turkey, and lettuce. Inclusivity and exclusivity testing revealed no false negatives and no false positives among the 50 L. monocytogenes serovars and 30 non-L. monocytogenes species examined. The method was shown to be robust when the enrichment times, volumes for DNA extraction, and heat block times were varied.

Berkeley Lab - Materials Sciences Division

Science.gov Websites

Synthesis Condensed Matter and Materials Physics Scattering and Instrumentation Science Centers Center for materials and phenomena at multiple time and length scales. Through our core programs and research centers Berkeley Lab Berkeley Lab A-Z Index Phone Book Jobs Search DOE Search MSD Go MSD - Materials

Scaling behavior in exclusive meson photoproduction from Jefferson Lab at large momentum transfers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dey, Biplab

2014-07-01

With the availability of new high-statistics and wide-angle measurements for several exclusive non-πN meson photoproduction channels from Jefferson Lab, we examine the fundamental scaling law of 90° scattering in QCD that was originally derived in the high-energy perturbative limit. The data show scaling to be prominently visible even in the medium-energy domain of 2.5 GeV ≲√s≲2.84 GeV, where √s is the center-of-mass energy. While constituent quark exchange suffices for pseudoscalar mesons, additional gluon exchanges from higher Fock states of the hadronic wave functions appear be needed for vector-meson production. Finally, the case of the Φ(1020), where two-gluon exchanges are knownmore » to dominate, is especially illuminating.« less

Advanced LabVIEW Labs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, Eric D.

1999-06-17

In the world of computer-based data acquisition and control, the graphical interface program LabVIEW from National Instruments is so ubiquitous that in many ways it has almost become the laboratory standard. To date, there have been approximately fifteen books concerning LabVIEW, but Professor Essick's treatise takes on a completely different tack than all of the previous discussions. In the more standard treatments of the ways and wherefores of LabVIEW such as LabVIEW Graphical Programming: Practical Applications in Instrumentation and Control by Gary W. Johnson (McGraw Hill, NY 1997), the emphasis has been instructing the reader how to program LabVIEW tomore » create a Virtual Instrument (VI) on the computer for interfacing to a particular instruments. LabVIEW is written in G a graphical programming language developed by National Instruments. In the past the emphasis has been on training the experimenter to learn G . Without going into details here, G incorporates the usual loops, arithmetic expressions, etc., found in many programming languages, but in an icon (graphical) environment. The net result being that LabVIEW contains all of the standard methods needed for interfacing to instruments, data acquisition, data analysis, graphics, and also methodology to incorporate programs written in other languages into LabVIEW. Historically, according to Professor Essick, he developed a series of experiments for an upper division laboratory course for computer-based instrumentation. His observation was that while many students had the necessary background in computer programming languages, there were students who had virtually no concept about writing a computer program let alone a computer- based interfacing program. Thus the beginnings of a concept for not only teaching computer- based instrumentation techniques, but aiso a method for the beginner to experience writing a com- puter program. Professor Essick saw LabVIEW as the perfect environment in which to teach

Advanced LabVIEW Labs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, Eric D.

1999-06-17

In the world of computer-based data acquisition and control, the graphical interface program LabVIEW from National Instruments is so ubiquitous that in many ways it has almost become the laboratory standard. To date, there have been approximately fifteen books concerning LabVIEW, but Professor Essick's treatise takes on a completely different tack than all of the previous discussions. In the more standard treatments of the ways and wherefores of LabVIEW such as LabVIEW Graphical Programming: Practical Applications in Instrumentation and Control by Gary W. Johnson (McGraw Hill, NY 1997), the emphasis has been instructing the reader how to program LabVIEW tomore » create a Virtual Instrument (VI) on the computer for interfacing to a particular instruments. LabVIEW is written in "G" a graphical programming language developed by National Instruments. In the past the emphasis has been on training the experimenter to learn "G". Without going into details here, "G" incorporates the usual loops, arithmetic expressions, etc., found in many programming languages, but in an icon (graphical) environment. The net result being that LabVIEW contains all of the standard methods needed for interfacing to instruments, data acquisition, data analysis, graphics, and also methodology to incorporate programs written in other languages into LabVIEW. Historically, according to Professor Essick, he developed a series of experiments for an upper division laboratory course for computer-based instrumentation. His observation was that while many students had the necessary background in computer programming languages, there were students who had virtually no concept about writing a computer program let alone a computer- based interfacing program. Thus the beginnings of a concept for not only teaching computer- based instrumentation techniques, but aiso a method for the beginner to experience writing a com- puter program. Professor Essick saw LabVIEW as the "perfect environment in which to

Beam experiments with the Grenoble test electron cyclotron resonance ion source at iThemba LABS.

PubMed

Thomae, R; Conradie, J; Fourie, D; Mira, J; Nemulodi, F; Kuechler, D; Toivanen, V

2016-02-01

At iThemba Laboratory for Accelerator Based Sciences (iThemba LABS) an electron cyclotron ion source was installed and commissioned. This source is a copy of the Grenoble Test Source (GTS) for the production of highly charged ions. The source is similar to the GTS-LHC at CERN and named GTS2. A collaboration between the Accelerators and Beam Physics Group of CERN and the Accelerator and Engineering Department of iThemba LABS was proposed in which the development of high intensity argon and xenon beams is envisaged. In this paper, we present beam experiments with the GTS2 at iThemba LABS, in which the results of continuous wave and afterglow operation of xenon ion beams with oxygen as supporting gases are presented.

Determination of pore-scale hydrate phase equilibria in sediments using lab-on-a-chip technology.

PubMed

Almenningen, Stian; Flatlandsmo, Josef; Kovscek, Anthony R; Ersland, Geir; Fernø, Martin A

2017-11-21

We present an experimental protocol for fast determination of hydrate stability in porous media for a range of pressure and temperature (P, T) conditions. Using a lab-on-a-chip approach, we gain direct optical access to dynamic pore-scale hydrate formation and dissociation events to study the hydrate phase equilibria in sediments. Optical pore-scale observations of phase behavior reproduce the theoretical hydrate stability line with methane gas and distilled water, and demonstrate the accuracy of the new method. The procedure is applicable for any kind of hydrate transitions in sediments, and may be used to map gas hydrate stability zones in nature.

Valx: A system for extracting and structuring numeric lab test comparison statements from text

PubMed Central

Hao, Tianyong; Liu, Hongfang; Weng, Chunhua

2017-01-01

Objectives To develop an automated method for extracting and structuring numeric lab test comparison statements from text and evaluate the method using clinical trial eligibility criteria text. Methods Leveraging semantic knowledge from the Unified Medical Language System (UMLS) and domain knowledge acquired from the Internet, Valx takes 7 steps to extract and normalize numeric lab test expressions: 1) text preprocessing, 2) numeric, unit, and comparison operator extraction, 3) variable identification using hybrid knowledge, 4) variable - numeric association, 5) context-based association filtering, 6) measurement unit normalization, and 7) heuristic rule-based comparison statements verification. Our reference standard was the consensus-based annotation among three raters for all comparison statements for two variables, i.e., HbA1c and glucose, identified from all of Type 1 and Type 2 diabetes trials in ClinicalTrials.gov. Results The precision, recall, and F-measure for structuring HbA1c comparison statements were 99.6%, 98.1%, 98.8% for Type 1 diabetes trials, and 98.8%, 96.9%, 97.8% for Type 2 Diabetes trials, respectively. The precision, recall, and F-measure for structuring glucose comparison statements were 97.3%, 94.8%, 96.1% for Type 1 diabetes trials, and 92.3%, 92.3%, 92.3% for Type 2 diabetes trials, respectively. Conclusions Valx is effective at extracting and structuring free-text lab test comparison statements in clinical trial summaries. Future studies are warranted to test its generalizability beyond eligibility criteria text. The open-source Valx enables its further evaluation and continued improvement among the collaborative scientific community. PMID:26940748

Valx: A System for Extracting and Structuring Numeric Lab Test Comparison Statements from Text.

PubMed

Hao, Tianyong; Liu, Hongfang; Weng, Chunhua

2016-05-17

To develop an automated method for extracting and structuring numeric lab test comparison statements from text and evaluate the method using clinical trial eligibility criteria text. Leveraging semantic knowledge from the Unified Medical Language System (UMLS) and domain knowledge acquired from the Internet, Valx takes seven steps to extract and normalize numeric lab test expressions: 1) text preprocessing, 2) numeric, unit, and comparison operator extraction, 3) variable identification using hybrid knowledge, 4) variable - numeric association, 5) context-based association filtering, 6) measurement unit normalization, and 7) heuristic rule-based comparison statements verification. Our reference standard was the consensus-based annotation among three raters for all comparison statements for two variables, i.e., HbA1c and glucose, identified from all of Type 1 and Type 2 diabetes trials in ClinicalTrials.gov. The precision, recall, and F-measure for structuring HbA1c comparison statements were 99.6%, 98.1%, 98.8% for Type 1 diabetes trials, and 98.8%, 96.9%, 97.8% for Type 2 diabetes trials, respectively. The precision, recall, and F-measure for structuring glucose comparison statements were 97.3%, 94.8%, 96.1% for Type 1 diabetes trials, and 92.3%, 92.3%, 92.3% for Type 2 diabetes trials, respectively. Valx is effective at extracting and structuring free-text lab test comparison statements in clinical trial summaries. Future studies are warranted to test its generalizability beyond eligibility criteria text. The open-source Valx enables its further evaluation and continued improvement among the collaborative scientific community.

Development and design of a late-model fitness test instrument based on LabView

NASA Astrophysics Data System (ADS)

Xie, Ying; Wu, Feiqing

2010-12-01

Undergraduates are pioneers of China's modernization program and undertake the historic mission of rejuvenating our nation in the 21st century, whose physical fitness is vital. A smart fitness test system can well help them understand their fitness and health conditions, thus they can choose more suitable approaches and make practical plans for exercising according to their own situation. following the future trends, a Late-model fitness test Instrument based on LabView has been designed to remedy defects of today's instruments. The system hardware consists of fives types of sensors with their peripheral circuits, an acquisition card of NI USB-6251 and a computer, while the system software, on the basis of LabView, includes modules of user register, data acquisition, data process and display, and data storage. The system, featured by modularization and an open structure, is able to be revised according to actual needs. Tests results have verified the system's stability and reliability.

Treatment of radioactive liquid effluents by reverse osmosis membranes: From lab-scale to pilot-scale.

PubMed

Combernoux, Nicolas; Schrive, Luc; Labed, Véronique; Wyart, Yvan; Carretier, Emilie; Moulin, Philippe

2017-10-15

The recent use of the reverse osmosis (RO) process at the damaged Fukushima-Daiichi nuclear power plant generated a growing interest in the application of this process for decontamination purposes. This study focused on the development of a robust RO process for decontamination of two kinds of liquid effluents: a contaminated groundwater after a nuclear disaster and a contaminated seawater during a nuclear accident. The SW30 HR membrane was selected among other in this study due to higher retentions (96% for Cs and 98% for Sr) in a true groundwater. Significant fouling and scaling phenomenon, attributed to calcium and strontium precipitation, were evidenced in this work: this underscored the importance of the lab scale experiment in the process. Validation of the separation performances on trace radionuclides concentration was performed with similar retention around 96% between surrogates Cs (inactive) and 137 Cs (radioactive). The scale up to a 2.6 m 2 spiral wound membrane led to equivalent retentions (around 96% for Cs and 99% for Sr) but lower flux values: this underlined that the hydrodynamic parameters (flowrate/cross-flow velocity) should be optimized. This methodology was also applied on the reconstituted seawater effluent: retentions were slightly lower than for the groundwater and the same hydrodynamic effects were observed on the pilot scale. Then, ageing of the membrane through irradiation experiments were performed. Results showed that the membrane active layer composition influenced the membrane resistance towards γ irradiation: the SW30 HR membrane performances (retention and permeability) were better than the Osmonics SE at 1 MGy. Finally, to supplement the scale up approach, the irradiation of a spiral wound membrane revealed a limited effect on the permeability and retention. This indicated that irradiation conditions need to be controlled for a further development of the process. Copyright © 2017 Elsevier Ltd. All rights reserved.

Reflections on Three Corporate Research Labs: Bell Labs, HP Labs, Agilent Labs

NASA Astrophysics Data System (ADS)

Hollenhorst, James

2008-03-01

This will be a personal reflection on corporate life and physics-based research in three industrial research labs over three decades, Bell Labs during the 1980's, HP Labs during the 1990's, and Agilent Labs during the 2000's. These were times of great change in all three companies. I'll point out some of the similarities and differences in corporate cultures and how this impacted the research and development activities. Along the way I'll mention some of the great products that resulted from physics-based R&D.

Beam experiments with the Grenoble test electron cyclotron resonance ion source at iThemba LABS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thomae, R., E-mail: rthomae@tlabs.ac.za; Conradie, J.; Fourie, D.

2016-02-15

At iThemba Laboratory for Accelerator Based Sciences (iThemba LABS) an electron cyclotron ion source was installed and commissioned. This source is a copy of the Grenoble Test Source (GTS) for the production of highly charged ions. The source is similar to the GTS-LHC at CERN and named GTS2. A collaboration between the Accelerators and Beam Physics Group of CERN and the Accelerator and Engineering Department of iThemba LABS was proposed in which the development of high intensity argon and xenon beams is envisaged. In this paper, we present beam experiments with the GTS2 at iThemba LABS, in which the resultsmore » of continuous wave and afterglow operation of xenon ion beams with oxygen as supporting gases are presented.« less

ERLN Lab Compendium Fact Sheet

EPA Pesticide Factsheets

The Compendium is an online database of environmental testing laboratories nationwide. It enables labs to create profiles of their capabilities, so emergency responders can quickly identify a lab that will meet their support needs.

Performance assessment and calibration of a profiling lab-scale acoustic Doppler velocimeter for application over mixed sand-gravel beds

USDA-ARS?s Scientific Manuscript database

Acoustic Doppler velocimetry has made high-resolution turbulence measurements in sediment-laden flows possible. Recent developments have resulted in a commercially available lab-scale acoustic Doppler profiling device, a Nortek Vectrino II, that allows for three-dimensional velocity data to be colle...

Lab-on-a-Chip Application Development-Portable Test System (LOCAD) Phase 2

NASA Image and Video Library

2009-03-21

ISS018-E-041370 (21 March 2009) --- Astronaut Sandra Magnus, STS-119 mission specialist, prepares to work with the Lab-on-a-Chip Application Development-Portable Test System (LOCAD-PTS) experiment in the Destiny laboratory while Space Shuttle Discovery remains docked with the International Space Station. LOCAD-PTS is a handheld device for rapid detection of biological and chemical substances onboard the station.

Using Saccharomyces cerevisiae to test the mutagenicity of household compounds: an open ended hypothesis-driven teaching lab.

PubMed

Marshall, Pamela A

2007-01-01

In our Fundamentals of Genetics lab, students perform a wide variety of labs to reinforce and extend the topics covered in lecture. I developed an active-learning lab to augment the lecture topic of mutagenesis. In this lab exercise, students determine if a compound they bring from home is a mutagen. Students are required to read extensive background material, perform research to find a potential mutagen to test, develop a hypothesis, and bring to the lab their own suspected mutagen. This lab uses a specially developed strain of Saccharomyces cerevisiae, D7, to determine if a compound is a mutagen. Mutagenesis of the D7 genome can lead to a scorable alteration in the phenotypes of this strain. Students outline and carry out a protocol for treatment of the yeast tester strain, utilizing the concept of dose/response and positive and negative controls. Students report on their results using a PowerPoint presentation to simulate giving a scientific presentation. The students' self-assessment of their knowledge indicated that, in all cases, the students felt that they knew more about the assay, mutagenesis, and the relationship between genotype and phenotype (P < 0.05) after completing the exercise.

Orodispersible films: Product transfer from lab-scale to continuous manufacturing.

PubMed

Thabet, Yasmin; Breitkreutz, Joerg

2018-01-15

Orodispersible films have been described as new beneficial dosage forms for special patient populations. Due to various production settings, different requirements on film formulations are required for non- continuous and continuous manufacturing. In this study, a continuous coating machine was qualified in regards of the process conditions for film compositions and their effects on the formed films. To investigate differences between both manufacturing processes, various film formulations of hydrochlorothiazide and hydroxypropylcellulose (HPC) or hydroxypropylmethycellulose (HPMC) as film formers were produced and the resulting films were characterized. The qualification of the continuously operating coating machine reveals no uniform heat distribution during drying. Coating solutions for continuous manufacturing should provide at least a dynamic viscosity of 1 Pa*s (wet film thickness of 500 μm, velocity of 15.9 cm/min). HPC films contain higher residuals of ethanol or acetone in bench-scale than in continuous production mode. Continuous production lead to lower drug content of the films. All continuously produced films disintegrate within less than 30 s. There are observed significant effects of the production process on the film characteristics. When transferring film manufacturing from lab-scale to continuous mode, film compositions, processing conditions and suitable characterization methods have to be carefully selected and adopted. Copyright © 2017 Elsevier B.V. All rights reserved.

Comparison between lab- and full-scale applications of in situ aeration of an old landfill and assessment of long-term emission development after completion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hrad, Marlies; Gamperling, Oliver; Huber-Humer, Marion, E-mail: marion.huber-humer@boku.ac.at

Highlights: ► Current data on in situ aeration effects from the first Austrian full-scale case study. ► Data on lasting waste stabilisation after aeration completion. ► Information on the transferability of results from lab- to full-scale aeration. - Abstract: Sustainable landfilling has become a fundamental objective in many modern waste management concepts. In this context, the in situ aeration of landfills has been recognised for its potential to convert conventional anaerobic landfills into biological stabilised state, whereby both current and potential (long-term) emissions of the landfilled waste are mitigated. In recent years, different in situ aeration concepts have been successfullymore » applied in Europe, North America and Asia, all pursuing different objectives and strategies. In Austria, the first full-scale application of in situ landfill aeration by means of low pressure air injection and simultaneous off-gas collection and treatment was implemented on an old, small municipal solid waste (MSW) landfill (2.6 ha) in autumn 2007. Complementary laboratory investigations were conducted with waste samples taken from the landfill site in order to provide more information on the transferability of the results from lab- to full-scale aeration measures. In addition, long-term emission development of the stabilised waste after aeration completion was assessed in an ongoing laboratory experiment. Although the initial waste material was described as mostly stable in terms of the biological parameters gas generation potential over 21 days (GP{sub 21}) and respiration activity over 4 days (RA{sub 4}), the lab-scale experiments indicated that aeration, which led to a significant improvement of leachate quality, was accompanied by further measurable changes in the solid waste material under optimised conditions. Even 75 weeks after aeration completion the leachate, as well as gaseous emissions from the stabilised waste material, remained low and stayed below

Experimental investigation of fuel regression rate in a HTPB based lab-scale hybrid rocket motor

NASA Astrophysics Data System (ADS)

Li, Xintian; Tian, Hui; Yu, Nanjia; Cai, Guobiao

2014-12-01

The fuel regression rate is an important parameter in the design process of the hybrid rocket motor. Additives in the solid fuel may have influences on the fuel regression rate, which will affect the internal ballistics of the motor. A series of firing experiments have been conducted on lab-scale hybrid rocket motors with 98% hydrogen peroxide (H2O2) oxidizer and hydroxyl terminated polybutadiene (HTPB) based fuels in this paper. An innovative fuel regression rate analysis method is established to diminish the errors caused by start and tailing stages in a short time firing test. The effects of the metal Mg, Al, aromatic hydrocarbon anthracene (C14H10), and carbon black (C) on the fuel regression rate are investigated. The fuel regression rate formulas of different fuel components are fitted according to the experiment data. The results indicate that the influence of C14H10 on the fuel regression rate of HTPB is not evident. However, the metal additives in the HTPB fuel can increase the fuel regression rate significantly.

The Development of MSFC Usability Lab

NASA Technical Reports Server (NTRS)

Cheng, Yiwei; Richardson, Sally

2010-01-01

This conference poster reviews the development of the usability lab at Marshall Space Flight Center. The purpose of the lab was to integrate a fully functioning usability laboratory to provide a resource for future human factor assessments. and to implement preliminary usability testing on a MSFC website to validate the functionality of the lab.

Toward Better Physics Labs for Future Biologists

NASA Astrophysics Data System (ADS)

Giannini, John; Moore, Kim; Losert, Wolfgang

2014-03-01

We have developed a set of laboratories and hands on activities to accompany a new two-semester interdisciplinary physics course that has been successfully developed and tested in two small test classes of students at the University of Maryland, College Park (UMD) in 2012-2013, and is currently being used on a wider scale. We have designed the laboratories to be taken accompanying a reformed course in the student's second year, with calculus, biology, and chemistry as prerequisites. This permits the laboratories to include significant content on physics relevant to cellular scales, from chemical interactions to random motion and charge screening in fluids. One major focus of the laboratories is to introduce the students to research-grade equipment and modern physics analysis tools in contexts relevant to biology, while maintaining the pedagogically valuable open-ended laboratory structure of reformed laboratories. Lab development procedures along with some preliminary student results from these two small test classes are discussed.

Solar photocatalitycal treatment of carbofuran at lab and pilot scale: effect of classical parameters, evaluation of the toxicity and analysis of organic by-products.

PubMed

Lopez-Alvarez, Blady; Torres-Palma, Ricardo A; Peñuela, Gustavo

2011-07-15

In this work the TiO(2) solar-photocatalytical degradation of the pesticide carbofuran (CBF) in water, at lab and pilot scale, was studied. At lab scale the evaluation of CBF concentration (14-282 μmol L(-1)) showed that the system followed a Langmuir-Hinshelwood kinetics type. TiO(2) concentration (0.05-2 g L(-1)) and initial pH (3-9) were also evaluated and optimized using the surface response methodology and the Pareto diagram. In the range of variables studied, initial pH 7.60 and 1.43 g L(-1) of TiO(2) favoured the efficiency of the process. Under optimal conditions the evolution of substrate, chemical oxygen demand, dissolved organic carbon, toxicity and organics by-products were evaluated. In the pilot scale tests, using direct sunlight, 55 mg L(-1) of CBF in a commercial formulation was eliminated after 420 min; while after 900 min of treatment 80% of toxicity (1/E(50) on Vibrium Fischeri), 80% of chemical oxygen demand and 60% of dissolved organic carbon were removed. The analysis and evolution of five CBF by-products, as well the evaluation of the treatment in the presence of isopropanol or using acetonitrile as a solvent suggest that the degradation is mainly carried out by OH radical attack. Finally, a schema depicting the main degradation pathway is proposed. Copyright © 2011 Elsevier B.V. All rights reserved.

Simultaneous Microwave Extraction and Separation of Volatile and Non-Volatile Organic Compounds of Boldo Leaves. From Lab to Industrial Scale

PubMed Central

Petigny, Loïc; Périno, Sandrine; Minuti, Matteo; Visinoni, Francesco; Wajsman, Joël; Chemat, Farid

2014-01-01

Microwave extraction and separation has been used to increase the concentration of the extract compared to the conventional method with the same solid/liquid ratio, reducing extraction time and separate at the same time Volatile Organic Compounds (VOC) from non-Volatile Organic Compounds (NVOC) of boldo leaves. As preliminary study, a response surface method has been used to optimize the extraction of soluble material and the separation of VOC from the plant in laboratory scale. The results from the statistical analysis revealed that the optimized conditions were: microwave power 200 W, extraction time 56 min and solid liquid ratio of 7.5% of plants in water. Lab scale optimized microwave method is compared to conventional distillation, and requires a power/mass ratio of 0.4 W/g of water engaged. This power/mass ratio is kept in order to upscale from lab to pilot plant. PMID:24776762

GeoLab: A Geological Workstation for Future Missions

NASA Technical Reports Server (NTRS)

Evans, Cynthia; Calaway, Michael; Bell, Mary Sue; Li, Zheng; Tong, Shuo; Zhong, Ye; Dahiwala, Ravi

2014-01-01

The GeoLab glovebox was, until November 2012, fully integrated into NASA's Deep Space Habitat (DSH) Analog Testbed. The conceptual design for GeoLab came from several sources, including current research instruments (Microgravity Science Glovebox) used on the International Space Station, existing Astromaterials Curation Laboratory hardware and clean room procedures, and mission scenarios developed for earlier programs. GeoLab allowed NASA scientists to test science operations related to contained sample examination during simulated exploration missions. The team demonstrated science operations that enhance theThe GeoLab glovebox was, until November 2012, fully integrated into NASA's Deep Space Habitat (DSH) Analog Testbed. The conceptual design for GeoLab came from several sources, including current research instruments (Microgravity Science Glovebox) used on the International Space Station, existing Astromaterials Curation Laboratory hardware and clean room procedures, and mission scenarios developed for earlier programs. GeoLab allowed NASA scientists to test science operations related to contained sample examination during simulated exploration missions. The team demonstrated science operations that enhance the early scientific returns from future missions and ensure that the best samples are selected for Earth return. The facility was also designed to foster the development of instrument technology. Since 2009, when GeoLab design and construction began, the GeoLab team [a group of scientists from the Astromaterials Acquisition and Curation Office within the Astromaterials Research and Exploration Science (ARES) Directorate at JSC] has progressively developed and reconfigured the GeoLab hardware and software interfaces and developed test objectives, which were to 1) determine requirements and strategies for sample handling and prioritization for geological operations on other planetary surfaces, 2) assess the scientific contribution of selective in-situ sample

Farm-scale testing of soybean peroxidase and calcium peroxide for surficial swine manure treatment and mitigation of odorous VOCs, ammonia and hydrogen sulfide

USDA-ARS?s Scientific Manuscript database

The swine industry, regulatory agencies, and the public are interested in farm-tested methods for controlling gaseous emissions from swine barns. In earlier lab- and pilot-scale studies, a renewable catalyst consisting of soybean peroxidase (SBP) mixed with calcium peroxide was found to be effective...

A versatile lab-on-chip test platform to characterize elementary deformation mechanisms and electromechanical couplings in nanoscopic objects

NASA Astrophysics Data System (ADS)

Pardoen, Thomas; Colla, Marie-Sthéphane; Idrissi, Hosni; Amin-Ahmadi, Behnam; Wang, Binjie; Schryvers, Dominique; Bhaskar, Umesh K.; Raskin, Jean-Pierre

2016-03-01

A nanomechanical on-chip test platform has recently been developed to deform under a variety of loading conditions freestanding thin films, ribbons and nanowires involving submicron dimensions. The lab-on-chip involves thousands of elementary test structures from which the elastic modulus, strength, strain hardening, fracture, creep properties can be extracted. The technique is amenable to in situ transmission electron microscopy (TEM) investigations to unravel the fundamental underlying deformation and fracture mechanisms that often lead to size-dependent effects in small-scale samples. The method allows addressing electrical and magnetic couplings as well in order to evaluate the impact of large mechanical stress levels on different solid-state physics phenomena. We had the chance to present this technique in details to Jacques Friedel in 2012 who, unsurprisingly, made a series of critical and very relevant suggestions. In the spirit of his legacy, the paper will address both mechanics of materials related phenomena and couplings with solids state physics issues.

Treatment of sanitary landfill leachates in a lab-scale gradual concentric chamber (GCC) reactor.

PubMed

Mendoza, Lourdes; Verstraete, Willy; Carballa, Marta

2010-03-01

Sanitary landfill leachates are a major environmental problem in South American countries where sanitary landfills are still constructed and appropriate designs for the treatment of these leachates remain problematic. The performance of a lab-scale Gradual Concentric Chamber (GCC) reactor for leachates treatment is presented in this study. Two types of sanitary landfill residuals were evaluated, one directly collected from the garbage trucks (JGL), with high organic strength (84 g COD/l) and the second one, a 6-month-generated leachate (YL) collected from the lagoon of the sanitary landfill in Quito, Ecuador, with an organic strength of 66 g COD/l. Different operational parameters, such as organic loading rate (OLR), temperature, recycling and aeration, were tested. The GCC reactor was found to be a robust technology to treat these high-strength streams with organic matter removal efficiencies higher than 65%. The best performance of the reactors (COD removal efficiencies of 75-80%) was obtained at a Hydraulic Retention Time (HRT) of around 20 h and at 35 degrees C, with an applied OLR up to 70 and 100 g COD/l per day. Overall, the GCC reactor concept appears worth to be further developed for the treatment of leachates in low-income countries.

Characterization of an Autotrophic Nitrogen-Removing Biofilm from a Highly Loaded Lab-Scale Rotating Biological Contactor

PubMed Central

Pynaert, Kris; Smets, Barth F.; Wyffels, Stijn; Beheydt, Daan; Siciliano, Steven D.; Verstraete, Willy

2003-01-01

In this study, a lab-scale rotating biological contactor (RBC) treating a synthetic NH4+ wastewater devoid of organic carbon and showing high N losses was examined for several important physiological and microbial characteristics. The RBC biofilm removed 89% ± 5% of the influent N at the highest surface load of approximately 8.3 g of N m−2 day−1, with N2 as the main end product. In batch tests, the RBC biomass showed good aerobic and anoxic ammonium oxidation (147.8 ± 7.6 and 76.5 ± 6.4 mg of NH4+-N g of volatile suspended solids [VSS]−1 day−1, respectively) and almost no nitrite oxidation (< 1 mg of N g of VSS−1 day−1). The diversity of aerobic ammonia-oxidizing bacteria (AAOB) and planctomycetes in the biofilm was characterized by cloning and sequencing of PCR-amplified partial 16S rRNA genes. Phylogenetic analysis of the clones revealed that the AAOB community was fairly homogeneous and was dominated by Nitrosomonas-like species. Close relatives of the known anaerobic ammonia-oxidizing bacterium (AnAOB) Kuenenia stuttgartiensis dominated the planctomycete community and were most probably responsible for anoxic ammonium oxidation in the RBC. Use of a less specific planctomycete primer set, not amplifying the AnAOB, showed a high diversity among other planctomycetes, with representatives of all known groups present in the biofilm. The spatial organization of the biofilm was characterized using fluorescence in situ hybridization (FISH) with confocal scanning laser microscopy (CSLM). The latter showed that AAOB occurred side by side with putative AnAOB (cells hybridizing with probe PLA46 and AMX820/KST1275) throughout the biofilm, while other planctomycetes hybridizing with probe PLA886 (not detecting the known AnAOB) were present as very conspicuous spherical structures. This study reveals that long-term operation of a lab-scale RBC on a synthetic NH4+ wastewater devoid of organic carbon yields a stable biofilm in which two bacterial groups, thought

Large-Scale Production of Carbon Nanotubes Using the Jefferson Lab Free Electron Laser

NASA Technical Reports Server (NTRS)

Holloway, Brian C.

2003-01-01

We report on our interdisciplinary program to use the Free Electron Laser (FEL) at the Thomas Jefferson National Accelerator Facility (J-Lab) for high-volume pulsed laser vaporization synthesis of carbon nanotubes. Based in part on the funding of from this project, a novel nanotube production system was designed, tested, and patented. Using this new system nanotube production rates over 100 times faster than conventional laser systems were achieved. Analysis of the material produced shows that it is of as high a quality as the standard laser-based materials.

EarthLabs: A National Model for Earth Science Lab Courses

NASA Astrophysics Data System (ADS)

McDaris, J. R.; Dahlman, L.; Barstow, D.

2008-12-01

As a response to the need for more rigorous, inquiry-based high school Earth science courses, a coalition of scientists, educators, and five states have created EarthLabs, a set of pilot modules that can serve as a national model for lab-based science courses. The content of EarthLabs chapters focuses on Earth system science and environmental literacy and conforms to the National Science Education Standards as well as the states' curriculum frameworks. The effort is funded by NOAA's Environmental Literacy program. The pilot modules present activities on Corals, Drought, Fisheries, and Hurricanes. The Fisheries and Hurricanes units were reviewed and field-tested by educators in Texas and Arizona. The feedback from this evaluation led to revisions of these units and guided development of the Corals and Drought chapters. Each module consists of activities that use online data sets, satellite imagery, web-based readings, and hands-on laboratory experiments. The project comprises two separate websites, one for the instructor and one for students. The instructor's site contains the pedagogical underpinnings for each lab including teaching materials, assessment strategies, and the alignment of activities with state and national science standards. The student site provides access to all materials that students need to complete the activities or, in the case of the hands-on labs, where they access additional information to help extend their learning. There are also formative and summative questions embedded in the student webpages to help scaffold learning through the activities.

Bituminous Mixtures Lab

DOT National Transportation Integrated Search

2002-07-25

The Bituminous Mixtures Laboratory (BML) specializes in the research of asphalt pavement mixtures. This lab supports FHWA's efforts to develop, evaluate and improve materials, mixture design technology and performance-based tests for asphalt paving m...

ExoGeoLab Pilot Project for Landers, Rovers and Instruments

NASA Astrophysics Data System (ADS)

Foing, Bernard

2010-05-01

We have developed a pilot facility with a Robotic Test Bench (ExoGeoLab) and a Mobile Lab Habitat (ExoHab). They can be used to validate concepts and external instruments from partner institutes. The ExoGeoLab research incubator project, has started in the frame of a collaboration between ILEWG (International Lunar Exploration working Group http://sci.esa.int/ilewg), ESTEC, NASA and academic partners, supported by a design and control desk in the European Space Incubator (ESI), as well as infrastructure. ExoGeoLab includes a sequence of technology and research pilot project activities: - Data analysis and interpretation of remote sensing and in-situ data, and merging of multi-scale data sets - Procurement and integration of geophysical, geo-chemical and astrobiological breadboard instruments on a surface station and rovers - Integration of cameras, environment and solar sensors, Visible and near IR spectrometer, Raman spectrometer, sample handling, cooperative rovers - Delivery of a generic small planetary lander demonstrator (ExoGeoLab lander, Sept 2009) as a platform for multi-instruments tests - Research operations and exploitation of ExoGeoLab test bench for various conceptual configurations, and support for definition and design of science surface packages (Moon, Mars, NEOs, outer moons) - Field tests of lander, rovers and instruments in analogue sites (Utah MDRS 2009 & 2010, Eifel volcanic park in Sept 2009, and future campaigns). Co-authors, ILEWG ExoGeoLab & ExoHab Team: B.H. Foing(1,11)*#, C. Stoker(2,11)*, P. Ehrenfreund(10,11), L. Boche-Sauvan(1,11)*, L. Wendt(8)*, C. Gross(8, 11)*, C. Thiel(9)*, S. Peters(1,6)*, A. Borst(1,6)*, J. Zavaleta(2)*, P. Sarrazin(2)*, D. Blake(2), J. Page(1,4,11), V. Pletser(5,11)*, E. Monaghan(1)*, P. Mahapatra(1)#, A. Noroozi(3), P. Giannopoulos(1,11) , A. Calzada(1,6,11), R. Walker(7), T. Zegers(1, 15) #, G. Groemer(12)# , W. Stumptner(12)#, B. Foing(2,5), J. K. Blom(3)#, A. Perrin(14)#, M. Mikolajczak(14)#, S. Chevrier(14

Perspectives on ecological research at the Outdoor StreamLab, a field-scale experimental stream

NASA Astrophysics Data System (ADS)

Merten, E. C.; Dieterman, D.; Kramarczuk, K.; Lightbody, A.; Orr, C. H.; Wellnitz, T.

2009-12-01

Artificial streams hold great promise for examining ecological processes. They lend themselves to manipulations of discharge, sediment load, water chemistry, and other parameters difficult or impossible to control in natural streams. However, artificial streams also have important limitations. In this presentation we describe insights gained from several ecological studies conducted at the St. Anthony Falls Laboratory’s Outdoor StreamLab, including, 1) short-term turbidity exposure effects on fish health, 2) macroinvertebrate grazing rates on periphyton as a function of velocity, 3) rates of macroinvertebrate colonization as related to velocity, and 4) fine-scale correlations of periphytic biomass with hydraulic conditions. Several lessons emerge from these initial attempts at ecological research in the Outdoor StreamLab. We have learned that the size, flow rate, substrate, water chemistry, and available colonization population of the artificial stream limit the kinds of organisms and types of ecological processes that can be examined and the types of experiments that can be run. We suggest that short-term biotic responses are best for study in a system of this type, and note that constant experiment maintenance is essential. Operating artificial streams to meet the needs of multiple researchers also presents challenges of scheduling, coordination, and conflict resolution. Although ecological research in artificial streams has considerable potential, the planning required is no less than that of traditional field studies.

Comparison between lab- and full-scale applications of in situ aeration of an old landfill and assessment of long-term emission development after completion.

PubMed

Hrad, Marlies; Gamperling, Oliver; Huber-Humer, Marion

2013-10-01

Sustainable landfilling has become a fundamental objective in many modern waste management concepts. In this context, the in situ aeration of landfills has been recognised for its potential to convert conventional anaerobic landfills into biological stabilised state, whereby both current and potential (long-term) emissions of the landfilled waste are mitigated. In recent years, different in situ aeration concepts have been successfully applied in Europe, North America and Asia, all pursuing different objectives and strategies. In Austria, the first full-scale application of in situ landfill aeration by means of low pressure air injection and simultaneous off-gas collection and treatment was implemented on an old, small municipal solid waste (MSW) landfill (2.6ha) in autumn 2007. Complementary laboratory investigations were conducted with waste samples taken from the landfill site in order to provide more information on the transferability of the results from lab- to full-scale aeration measures. In addition, long-term emission development of the stabilised waste after aeration completion was assessed in an ongoing laboratory experiment. Although the initial waste material was described as mostly stable in terms of the biological parameters gas generation potential over 21days (GP21) and respiration activity over 4days (RA4), the lab-scale experiments indicated that aeration, which led to a significant improvement of leachate quality, was accompanied by further measurable changes in the solid waste material under optimised conditions. Even 75weeks after aeration completion the leachate, as well as gaseous emissions from the stabilised waste material, remained low and stayed below the authorised Austrian discharge limits. However, the application of in situ aeration at the investigated landfill is a factor 10 behind the lab-based predictions after 3years of operation, mainly due to technical limitations in the full-scale operation (e.g. high air flow resistivity due

Stream piracy in the Black Hills: A geomorphology lab exercise

USGS Publications Warehouse

Zaprowski, B.J.; Evenson, E.B.; Epstein, J.B.

2002-01-01

The Black Hills of South Dakota exhibits many fine examples of stream piracy that are very suitable for teaching geomorphology lab exercises. This lab goes beyond standard topographic map interpretation by using geologic maps, well logs, gravel provenance and other types of data to teach students about stream piracy. Using a step-by-step method in which the lab exercises ramp up in difficulty, students hone their skills in deductive reasoning and data assimilation. The first exercises deal with the identification of stream piracy at a variety of spatial scales and the lab culminates with an exercise on landscape evolution and drainage rearrangement.

A spatially explicit hydro-ecological modeling framework (BEPS-TerrainLab V2.0): Model description and test in a boreal ecosystem in Eastern North America

NASA Astrophysics Data System (ADS)

Govind, Ajit; Chen, Jing Ming; Margolis, Hank; Ju, Weimin; Sonnentag, Oliver; Giasson, Marc-André

2009-04-01

SummaryA spatially explicit, process-based hydro-ecological model, BEPS-TerrainLab V2.0, was developed to improve the representation of ecophysiological, hydro-ecological and biogeochemical processes of boreal ecosystems in a tightly coupled manner. Several processes unique to boreal ecosystems were implemented including the sub-surface lateral water fluxes, stratification of vegetation into distinct layers for explicit ecophysiological representation, inclusion of novel spatial upscaling strategies and biogeochemical processes. To account for preferential water fluxes common in humid boreal ecosystems, a novel scheme was introduced based on laboratory analyses. Leaf-scale ecophysiological processes were upscaled to canopy-scale by explicitly considering leaf physiological conditions as affected by light and water stress. The modified model was tested with 2 years of continuous measurements taken at the Eastern Old Black Spruce Site of the Fluxnet-Canada Research Network located in a humid boreal watershed in eastern Canada. Comparison of the simulated and measured ET, water-table depth (WTD), volumetric soil water content (VSWC) and gross primary productivity (GPP) revealed that BEPS-TerrainLab V2.0 simulates hydro-ecological processes with reasonable accuracy. The model was able to explain 83% of the ET, 92% of the GPP variability and 72% of the WTD dynamics. The model suggests that in humid ecosystems such as eastern North American boreal watersheds, topographically driven sub-surface baseflow is the main mechanism of soil water partitioning which significantly affects the local-scale hydrological conditions.

Lab-on a-Chip

NASA Technical Reports Server (NTRS)

2003-01-01

Helen Cole, the project manager for the Lab-on-a-Chip Applications Development program, and Lisa Monaco, the project scientist for the program, insert a lab on a chip into the Caliper 42 which is specialized equipment that controls processes on commercial chips to support development of lab-on-a-chip applications. The system has special microscopes and imaging systems, so scientists can process and study different types of fluid, chemical, and medical tests conducted on chips. For example, researchers have examined fluorescent bacteria as it flows through the chips' fluid channels or microfluidic capillaries. Researchers at NASA's Marshall Space Flight Center (MSFC) in Huntsville, Alabama, have been studying how the lab-on-a-chip technology can be used for microbial detection, water quality monitoring, and detecting biosignatures of past or present life on Mars. The Marshall Center team is also collaborating with scientists at other NASA centers and at universities to develop custom chip designs for not only space applications, but for many Earth applications, such as for detecting deadly microbes in heating and air systems. (NASA/MSFC/D.Stoffer)

What Is LAB and Why Was It Renormed?

ERIC Educational Resources Information Center

Abbott, Muriel

A report on the Language Assessment Battery (LAB) explains, in question-and-answer form, the causes and results of some changes made in the test norms. The LAB is a test of communicative language competence, written in English and Spanish versions and used for student placement in the New York City Public Schools. The report describes the test…

Bacterial community structure of a lab-scale anammox membrane bioreactor.

PubMed

Gonzalez-Martinez, Alejandro; Osorio, F; Rodriguez-Sanchez, Alejandro; Martinez-Toledo, Maria Victoria; Gonzalez-Lopez, Jesus; Lotti, Tommaso; van Loosdrecht, M C M

2015-01-01

Autotrophic nitrogen removal technologies have proliferated through the last decade. Among these, a promising one is the membrane bioreactor (MBR) Anammox, which can achieve very high solids retention time and therefore sets a proper environment for the cultivation of anammox bacteria. In this sense, the MBR Anammox is an efficient technology for the treatment of effluents with low organic carbon and high ammonium concentrations once it has been treated under partial nitrification systems. A lab-scale MBR Anammox bioreactor has been built at the Technological University of Delft, The Netherlands and has been proven for efficient nitrogen removal and efficient cultivation of anammox bacteria. In this study, next-generation sequencing techniques have been used for the investigation of the bacterial communities of this MBR Anammox for the first time ever. A strong domination of Candidatus Brocadia bacterium and also the presence of a myriad of other microorganisms that have adapted to this environment were detected, suggesting that the MBR Anammox bioreactor might have a more complex microbial ecosystem that it has been thought. Among these, nitrate-reducing heterotrophs and primary producers, among others, were identified. Definition of the ecological roles of the OTUs identified through metagenomic analysis was discussed. © 2014 American Institute of Chemical Engineers.

Portable Anthrax Testing with Lab-in-a-Pocket

ScienceCinema

Finley, Melissa; Koskelo, Markku; Edwards, Thayne

2018-05-30

BaDx (Bacillus anthracis Diagnostics) is a lab-in-a-pocket device to sample, sense, and diagnose bacteria that cause anthrax. It accomplishes these tasks in environments with no power, refrigerated storage, or laboratory equipment. BaDx was designed to be used with minimal or no training, and to keep handlers safe.

Portable Anthrax Testing with Lab-in-a-Pocket

DOE Office of Scientific and Technical Information (OSTI.GOV)

Finley, Melissa; Koskelo, Markku; Edwards, Thayne

2014-10-24

BaDx (Bacillus anthracis Diagnostics) is a lab-in-a-pocket device to sample, sense, and diagnose bacteria that cause anthrax. It accomplishes these tasks in environments with no power, refrigerated storage, or laboratory equipment. BaDx was designed to be used with minimal or no training, and to keep handlers safe.

Love the Lab, Hate the Lab Report?

ERIC Educational Resources Information Center

Bjorn, Genevive

2018-01-01

In the author's large, urban high school, enrollment in a laboratory science is mandatory. While the student participation rate for lab activities is over 98%, the turn-in rate for traditional lab reports averages just 35% to 85%. Those students who don't produce a lab report miss a critical opportunity to improve their skills in scientific…

Establishment of a new in vitro test method for evaluation of eye irritancy using a reconstructed human corneal epithelial model, LabCyte CORNEA-MODEL.

PubMed

Katoh, Masakazu; Hamajima, Fumiyasu; Ogasawara, Takahiro; Hata, Ken-ichiro

2013-12-01

Finding in vitro eye irritation testing alternatives to animal testing such as the Draize eye test, which uses rabbits, is essential from the standpoint of animal welfare. It has been developed a reconstructed human corneal epithelial model, the LabCyte CORNEA-MODEL, which has a representative corneal epithelium-like structure. Protocol optimization (pre-validation study) was examined in order to establish a new alternative method for eye irritancy evaluation with this model. From the results of the optimization experiments, the application periods for chemicals were set at 1min for liquid chemicals or 24h for solid chemicals, and the post-exposure incubation periods were set at 24h for liquids or zero for solids. If the viability was less than 50%, the chemical was judged to be an eye irritant. Sixty-one chemicals were applied in the optimized protocol using the LabCyte CORNEA-MODEL and these results were evaluated in correlation with in vivo results. The predictions of the optimized LabCyte CORNEA-MODEL eye irritation test methods were highly correlated with in vivo eye irritation (sensitivity 100%, specificity 80.0%, and accuracy 91.8%). These results suggest that the LabCyte CORNEA-MODEL eye irritation test could be useful as an alternative method to the Draize eye test. Copyright © 2013 Elsevier Ltd. All rights reserved.

Lab on a Chip Application Development for Exploration

NASA Technical Reports Server (NTRS)

Monaco, Lisa

2004-01-01

At Marshall Space Flight Center a new capability has been established to aid the advancement of microfluidics for space flight monitoring systems. Lab-On-a-Chip Application Development (LOCAD) team has created a program for advancing Technology Readiness Levels (TRL) of 1 & 2 to TRL 6 and 7, quickly and economically for Lab-On-a-Chip (LOC) applications. Scientists and engineers can utilize LOCAD's process to efficiently learn about microfluidics and determine if microfluidics is applicable to their needs. Once the applicability has been determined, LOCAD can then perform tests to develop the new fluidic protocols which are different from macro-scale chemical reaction protocols. With this information new micro-devices can be created such as the development of a microfluidic system to aid in the search for life, past and present, on Mars. Particular indicators in the Martian soil can contain the direct evidence of life. But to extract the information from the soil and present it to the proper detectors requires multiple fluidic/chemical operations. This is where LOCAD is providing its unique abilities.

Traditional Labs + New Questions = Improved Student Performance.

ERIC Educational Resources Information Center

Rezba, Richard J.; And Others

1992-01-01

Presents three typical lab activities involving the breathing rate of fish, the behavior of electromagnets, and tests for water hardness to demonstrate how labs can be modified to teach process skills. Discusses how basic concepts about experimentation are developed and ways of generating and improving science experiments. Includes a laboratory…

Jefferson Lab Virtual Tour

ScienceCinema

None

2018-01-16

Take a virtual tour of the campus of Thomas Jefferson National Accelerator Facility. You can see inside our two accelerators, three experimental areas, accelerator component fabrication and testing areas, high-performance computing areas and laser labs.

Lab experiments investigating astrophysical jet physics

NASA Astrophysics Data System (ADS)

Bellan, Paul

2014-10-01

Dynamics relevant to astrophysical plasmas is being investigated in lab experiments having similar physics and topology, but much smaller time and space scales. High speed movies and numerical simulations both show that highly collimated MHD-driven plasma flows are a critical feature; these collimated flows can be considered to be a lab version of an astrophysical jet. Having both axial and azimuthal magnetic fields, the jet is effectively an axially lengthening plasma-confining flux tube with embedded helical magnetic field (flux rope). The jet velocity is in good agreement with an MHD acceleration model. Axial stagnation of the jet compresses embedded azimuthal magnetic flux and so results in jet self-collimation. Jets kink when they breach the Kruskal-Shafranov stability limit. The lateral acceleration of a sufficiently strong kink can provide an effective gravity which provides the environment for a spontaneously-developing, fine-scale, extremely fast Rayleigh-Taylor instability that erodes the current channel to be smaller than the ion skin depth. This cascade from the ideal MHD scale of the kink to the non-MHD ion skin depth scale can result in a fast magnetic reconnection whereby the jet breaks off from its source electrode. Supported by USDOE and NSF.

The NASA Langley Isolator Dynamics Research Lab

NASA Technical Reports Server (NTRS)

Middleton, Troy F.; Balla, Robert J.; Baurle, Robert A.; Humphreys, William M.; Wilson, Lloyd G.

2010-01-01

The Isolator Dynamics Research Lab (IDRL) is under construction at the NASA Langley Research Center in Hampton, Virginia. A unique test apparatus is being fabricated to support both wall and in-stream measurements for investigating the internal flow of a dual-mode scramjet isolator model. The test section is 24 inches long with a 1-inch by 2-inch cross sectional area and is supplied with unheated, dry air through a Mach 2.5 converging-diverging nozzle. The test section is being fabricated with two sets (glass and metallic) of interchangeable sidewalls to support flow visualization and laser-based measurement techniques as well as static pressure, wall temperature, and high frequency pressure measurements. During 2010, a CFD code validation experiment will be conducted in the lab in support of NASA s Fundamental Aerodynamics Program. This paper describes the mechanical design of the Isolator Dynamics Research Lab test apparatus and presents a summary of the measurement techniques planned for investigating the internal flow field of a scramjet isolator model.

Lab Test Information

MedlinePlus

... Mumps Tests MPV Blood Test Mucus in Urine N Nitrites in Urine P Pap Smear Porphyrin Test ... V Vitamin D Test Vitamin E (tocopherol) Test Y Yeast Infection Test Related MedlinePlus Health Topics Laboratory ...

Effects of different nitrogen sources on the biogas production - a lab-scale investigation.

PubMed

Wagner, Andreas Otto; Hohlbrugger, Peter; Lins, Philipp; Illmer, Paul

2012-12-20

For anaerobic digestion processes nitrogen sources are poorly investigated although they are known as possible process limiting factors (in the hydrolysis phase) but also as a source for fermentations for subsequent methane production by methanogenic archaea. In the present study different complex and defined nitrogen sources were investigated in a lab-scale experiment in order to study their potential to build up methane. The outcome of the study can be summarised as follows: from complex nitrogen sources yeast extract and casamino acids showed the highest methane production with approximately 600 ml methane per mole of nitrogen, whereas by the use of skim milk no methane production could be observed. From defined nitrogen sources L-arginine showed the highest methane production with almost 1400 ml methane per mole of nitrogen. Moreover it could be demonstrated that the carbon content and therefore C/N-ratio has only minor influence for the methane production from the used substrates. Copyright © 2011 Elsevier GmbH. All rights reserved.

Evaluation of Methods to Select Scale Velocities in Icing Scaling Tests

NASA Technical Reports Server (NTRS)

Anderson, David N.; Ruff, Gary A.; Bond, Thomas H. (Technical Monitor)

2003-01-01

A series of tests were made in the NASA Glenn Icing Research Tunnel to determine how icing scaling results were affected by the choice of scale velocity. Reference tests were performed with a 53.3-cm-chord NACA 0012 airfoil model, while scale tests used a 27.7-cm-chord 0012 model. Tests were made with rime, mixed, and glaze ice. Reference test conditions included airspeeds of 67 and 89 m/s, an MVD of 40 microns, and LWCs of 0.5 and 0.6 g/cu m. Scale test conditions were established by the modified Ruff (AEDC) scaling method with the scale velocity determined in five ways. The resulting scale velocities ranged from 85 to 220 percent of the reference velocity. This paper presents the ice shapes that resulted from those scale tests and compares them to the reference shapes. It was concluded that for freezing fractions greater than 0.8 as well as for a freezing fraction of 0.3, the value of the scale velocity had no effect on how well the scale ice shape simulated the reference shape. For freezing fractions of 0.5 and 0.7, the simulation of the reference shape appeared to improve as the scale velocity increased.

Allergen screening bioassays: recent developments in lab-on-a-chip and lab-on-a-disc systems.

PubMed

Ho, Ho-pui; Lau, Pui-man; Kwok, Ho-chin; Wu, Shu-yuen; Gao, Minghui; Cheung, Anthony Ka-lun; Chen, Qiulan; Wang, Guanghui; Kwan, Yiu-wa; Wong, Chun-kwok; Kong, Siu-kai

2014-01-01

Allergies occur when a person's immune system mounts an abnormal response with or without IgE to a normally harmless substance called an allergen. The standard skin-prick test introduces suspected allergens into the skin with lancets in order to trigger allergic reactions. This test is annoying and sometimes life threatening. New tools such as lab-on-a-chip and lab-on-a-disc, which rely on microfabrication, are designed for allergy testing. These systems provide benefits such as short analysis times, enhanced sensitivity, simplified procedures, minimal consumption of sample and reagents and low cost. This article gives a summary of these systems. In particular, a cell-based assay detecting both the IgE- and non-IgE-type triggers through the study of degranulation in a centrifugal microfluidic system is highlighted.

Devolatilization of oil sludge in a lab-scale bubbling fluidized bed.

PubMed

Liu, Jianguo; Jiang, Xiumin; Han, Xiangxin

2011-01-30

Devolatilization of oil sludge pellets was investigated in nitrogen and air atmosphere in a lab-scale bubbling fluidized bed (BFB). Devolatilization times were measured by the degree of completion of the evolution of the volatiles for individual oil sludge pellets in the 5-15 mm diameter range. The influences of pellet size, bed temperature and superficial fluidization velocity on devolatilization time were evaluated. The variation of devolatilization time with particle diameter was expressed by the correlation, τ(d) = Ad(p)(N). The devolatilization time to pellet diameter curve shows nearly a linear increase in nitrogen, whereas an exponential increase in air. No noticeable effect of superficial fluidization velocity on devolatilization time in air atmosphere was observed. The behavior of the sludge pellets in the BFB was also focused during combustion experiments, primary fragmentation (a micro-explosive combustion phenomenon) was observed for bigger pellets (>10mm) at high bed temperatures (>700 °C), which occurred towards the end of combustion and remarkably reduce the devolatilization time of the oil sludge pellet. The size analysis of bed materials and fly ash showed that entire ash particle was entrained or elutriated out of the BFB furnace due to the fragile structure of oil sludge ash particles. Copyright © 2010 Elsevier B.V. All rights reserved.

76 FR 50881 - Required Scale Tests

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-17

... RIN 0580-AB10 Required Scale Tests AGENCY: Grain Inspection, Packers and Stockyards Administration... required scale tests. Those documents defined ``limited seasonal basis'' incorrectly. This document... 20, 2011 (76 FR 3485) and on April 4, 2011 (76 FR 18348), concerning required scale tests. Those...

Consensus on Intermediate Scale Salt Field Test Design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kuhlman, Kristopher L.; Mills, Melissa Marie; Matteo, Edward N.

This report summarizes the first stage in a collaborative effort by Sandia, Los Alamos, and Lawrence Berkeley National Laboratories to design a small-diameter borehole heater test in salt at the Waste Isolation Pilot Plant (WIPP) for the US Department of Energy Office of Nuclear Energy (DOE-NE). The intention is to complete test design during the remainder of fiscal year 2017 (FY17), and the implementation of the test will begin in FY18. This document is the result of regular meetings between the three national labs and the DOE-NE, and is intended to represent a consensus of these meetings and discussions.

EUSO@TurLab: An experimental replica of ISS orbits

NASA Astrophysics Data System (ADS)

Bertaina, M.; Bowaire, A.; Cambursano, S.; Caruso, R.; Contino, G.; Cotto, G.; Crivello, F.; Forza, R.; Guardone, N.; Manfrin, M.; Mignone, M.; Mulas, R.; Suino, G.; Tibaldi, P. S.

2015-03-01

The EUSO@TurLab project is an on-going activity aimed to reproduce atmospheric and luminous conditions that JEM-EUSO will encounter on its orbits around the Earth. The use of the TurLab facility, part of the Department of Physics of the University of Torino, allows the simulation of different surface conditions in a very dark and rotating environment in order to test the response of JEM-EUSO's sensors and sensitivity. The experimental setup currently in operation has been used to check the potential of the TurLab facility for the above purposes, and the acquired data will be used to test the concept of JEM-EUSO's trigger system.

Detecting and Correcting Scale Drift in Test Equating: An Illustration from a Large Scale Testing Program

ERIC Educational Resources Information Center

Puhan, Gautam

2009-01-01

The purpose of this study is to determine the extent of scale drift on a test that employs cut scores. It was essential to examine scale drift for this testing program because new forms in this testing program are often put on scale through a series of intermediate equatings (known as equating chains). This process may cause equating error to…

Monitoring CO2 invasion processes at the pore scale using geological labs on chip.

PubMed

Morais, S; Liu, N; Diouf, A; Bernard, D; Lecoutre, C; Garrabos, Y; Marre, S

2016-09-21

In order to investigate at the pore scale the mechanisms involved during CO2 injection in a water saturated pore network, a series of displacement experiments is reported using high pressure micromodels (geological labs on chip - GLoCs) working under real geological conditions (25 < T (°C) < 75 and 4.5 < p (MPa) < 8). The experiments were focused on the influence of three experimental parameters: (i) the p, T conditions, (ii) the injection flow rates and (iii) the pore network characteristics. By using on-chip optical characterization and imaging approaches, the CO2 saturation curves as a function of either time or the number of pore volume injected were determined. Three main mechanisms were observed during CO2 injection, namely, invasion, percolation and drying, which are discussed in this paper. Interestingly, besides conventional mechanisms, two counterintuitive situations were observed during the invasion and drying processes.

SMR Re-Scaling and Modeling for Load Following Studies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hoover, K.; Wu, Q.; Bragg-Sitton, S.

2016-11-01

This study investigates the creation of a new set of scaling parameters for the Oregon State University Multi-Application Small Light Water Reactor (MASLWR) scaled thermal hydraulic test facility. As part of a study being undertaken by Idaho National Lab involving nuclear reactor load following characteristics, full power operations need to be simulated, and therefore properly scaled. Presented here is the scaling analysis and plans for RELAP5-3D simulation.

76 FR 3485 - Required Scale Tests

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-20

...-AB10 Required Scale Tests AGENCY: Grain Inspection, Packers and Stockyards Administration, USDA. ACTION... rule requires that regulated entities complete the first of the two scale tests between January 1 and June 30 of the calendar year. The remaining scale test must be completed between July 1 and December 31...

Berkeley Lab Training

Science.gov Websites

Berkeley Lab Berkeley Lab A-Z Index Phone Book Jobs Search DOE Help Berkeley Lab Training Welcome Welcome to Berkeley Lab Training! Login to access your LBNL Training Profile. This provides quick access to all of the courses you need. Look below, to learn about different types of training available at

E-Labs - Learning with Authentic Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bardeen, Marjorie G.; Wayne, Mitchell

the success teachers have had providing an opportunity for students to: • Organize and conduct authentic research. • Experience the environment of scientific collaborations. • Possibly make real contributions to a burgeoning scientific field. We've created projects that are problem-based, student driven and technology dependent. Students reach beyond classroom walls to explore data with other students and experts and share results, publishing original work to a worldwide audience. Students can discover and extend the research of other students, modeling the processes of modern, large-scale research projects. From start to finish e-Labs are student-led, teacher-guided projects. Students need only a Webmore » browser to access computing techniques employed by professional researchers. A Project Map with milestones allows students to set the research plan rather than follow a step-by-step process common in other online projects. Most importantly, e-Labs build the learning experience around the students' own questions and let them use the very tools that scientists use. Students contribute to and access shared data, most derived from professional research databases. They use common analysis tools, store their work and use metadata to discover, replicate and confirm the research of others. This is where real scientific collaboration begins. Using online tools, students correspond with other research groups, post comments and questions, prepare summary reports, and in general participate in the part of scientific research that is often left out of classroom experiments. Teaching tools such as student and teacher logbooks, pre- and post-tests and an assessment rubric aligned with learner outcomes help teachers guide student work. Constraints on interface designs and administrative tools such as registration databases give teachers the "one-stop-shopping" they seek for multiple e-Labs. Teaching and administrative tools also allow us to track usage and assess the

Methods for Scaling Icing Test Conditions

NASA Technical Reports Server (NTRS)

Anderson, David N.

1995-01-01

This report presents the results of tests at NASA Lewis to evaluate several methods to establish suitable alternative test conditions when the test facility limits the model size or operating conditions. The first method was proposed by Olsen. It can be applied when full-size models are tested and all the desired test conditions except liquid-water content can be obtained in the facility. The other two methods discussed are: a modification of the French scaling law and the AEDC scaling method. Icing tests were made with cylinders at both reference and scaled conditions representing mixed and glaze ice in the NASA Lewis Icing Research Tunnel. Reference and scale ice shapes were compared to evaluate each method. The Olsen method was tested with liquid-water content varying from 1.3 to .8 g/m(exp3). Over this range, ice shapes produced using the Olsen method were unchanged. The modified French and AEDC methods produced scaled ice shapes which approximated the reference shapes when model size was reduced to half the reference size for the glaze-ice cases tested.

Improving the Testing Environment of a Lab Transition-Edge Sensor: An Exercise in Nulling Earth’s Magnetic Field

NASA Astrophysics Data System (ADS)

Melton, Casey; McCammon Lab at University of Wisconsin-Madison

2018-01-01

In Dr. Dan McCammon’s lab at the University of Wisconsin-Madison, a special class of x-ray microcalorimeter called a Transition-Edge Sensor, or TES, is being tested in order to identify the strengths and weaknesses of this device in detecting x-ray photons from astronomical sources. The TES is currently housed in a cryogenic refrigerator where it can be tested at superconducting temperatures. Although this refrigerator is equipped with magnetic field shielding to keep magnetic fields out during testing, latent magnetic fields are trapped inside the receptacle at the time of cool-down. To remedy this problem, I built a set of tri-axial Helmholtz coils, which have at their center a uniform volume of magnetic field. This uniform region can be tuned prior to cool-down and nulls the magnetic field that would typically be trapped inside the receptacle. The magnetic field will be monitored inside the receptacle with a tri-axial fluxgate magnetic field sensor, which I began designing in the latter half of the project. This project is still in progress, and will be implemented in the lab in the near future.

Living Lab as an Agile Approach in Developing User-Friendly Welfare Technology.

PubMed

Holappa, Niina; Sirkka, Andrew

2017-01-01

This paper discusses living lab as a method of developing user-friendly welfare technology, and presents a qualitative evaluation research of how living lab tested technologies impacted on the life of healthcare customers and professionals over test periods.

Using "Saccharomyces cerevisiae" to Test the Mutagenicity of Household Compounds: An Open Ended Hypothesis-Driven Teaching Lab

ERIC Educational Resources Information Center

Marshall, Pamela A.

2007-01-01

In our Fundamentals of Genetics lab, students perform a wide variety of labs to reinforce and extend the topics covered in lecture. I developed an active-learning lab to augment the lecture topic of mutagenesis. In this lab exercise, students determine if a compound they bring from home is a mutagen. Students are required to read extensive…

Testing of the high accuracy inertial navigation system in the Shuttle Avionics Integration Lab

NASA Technical Reports Server (NTRS)

Strachan, Russell L.; Evans, James M.

1991-01-01

The description, results, and interpretation is presented of comparison testing between the High Accuracy Inertial Navigation System (HAINS) and KT-70 Inertial Measurement Unit (IMU). The objective was to show the HAINS can replace the KT-70 IMU in the space shuttle Orbiter, both singularly and totally. This testing was performed in the Guidance, Navigation, and Control Test Station (GTS) of the Shuttle Avionics Integration Lab (SAIL). A variety of differences between the two instruments are explained. Four, 5 day test sessions were conducted varying the number and slot position of the HAINS and KT-70 IMUs. The various steps in the calibration and alignment procedure are explained. Results and their interpretation are presented. The HAINS displayed a high level of performance accuracy previously unseen with the KT-70 IMU. The most significant improvement of the performance came in the Tuned Inertial/Extended Launch Hold tests. The HAINS exceeded the 4 hr specification requirement. The results obtained from the SAIL tests were generally well beyond the requirements of the procurement specification.

Reduction of spermatogonia and testosterone in rat testes flown on Space Lab-3

NASA Technical Reports Server (NTRS)

Philpott, Delbert E.; Stevenson, J.; Black, S.; Sapp, W.; Williams, C.

1986-01-01

The effects of space flight on rat testes were investigated. The weight, spermatogonial cell count, and testosterone levels in six rats flown on Space Lab-3 were measured. It is observed that compared to ground control rats the average weight loss was 7.1 percent and the spermatogonial cell count decreased by 7.5 percent. The data reveal that the testosterone level for large control rats was 9.13 ng/ml and 0.31 ng/ml for flight rats; and 2.54 ng/ml and 0.233 ng/ml for smaller control and flight rats, respectively. It is noted that spermatogenesis and testosterone production are reduced during spaceflight.

LabLessons: Effects of Electronic Prelabs on Student Engagement and Performance

ERIC Educational Resources Information Center

Gryczka, Patrick; Klementowicz, Edward; Sharrock, Chappel; Maxfield, MacRae; Montclare, Jin Kim

2016-01-01

Lab instructors, for both high school and undergraduate college level courses, face issues of constricted time within the lab period and limited student engagement with prelab materials. To address these issues, an online prelab delivery system named LabLessons is developed and tested out in a high school chemistry classroom. The system…

Gas hydrate dissociation via in situ combustion of methane - lab studies and field tests

NASA Astrophysics Data System (ADS)

Luzi-Helbing, Manja; Schicks, Judith M.; Spangenberg, Erik; Giese, Ronny

2013-04-01

In general, three different methods for gas hydrate production are known: thermal stimulation, pressure reduction, and chemical stimulation. In the framework of the German joint project SUGAR (Submarine Gas Hydrate Reservoirs: exploration, extraction and transport) a countercurrent heat exchange reactor was developed at GFZ which has been designed to decompose gas hydrates in sediments via thermal stimulation. The heat is produced by the catalytic oxidation of methane. The advantage of this method is that the heat is generated in place i.e. within the borehole on the same level like the hydrate-bearing sediments. The system is closed which means that there is no contact between the products or catalyst and the environment. The power output and the temperature of the reactor are regulated via the volume flow of the feed gases air and methane. Therefore, the catalytic reaction runs temperature-controlled, autothermic and safe. So far, a lab-scale prototype of the reactor (outer diameter 40 mm, length 457 mm) was successfully tested in a large reservoir simulator (LARS) which was set up at GFZ. Pt, Pd and Ir on ZrO2 as carrier material turned out to be a robust and reliable catalyst. This work presents results of the latest reactor test for which LARS was filled with sand, and ca. 80 % of the pore space was saturated with methane hydrate. To form hydrates the pore pressure and the confining pressure were kept at 8 MPa and 12 MPa, respectively, and the temperature was set to 278 K. During the start sequence the reactor was ignited at room temperature with hydrogen. By the time the reactor temperature reached ca. 523 K (ca. 15 min after hydrogen ignition) the fuel flow was changed to methane. After 9 hours all temperature sensors which are spatially distributed in LARS showed a temperature above the equilibrium temperature of 282 K at 8 MPa. All in all, the reactor was run for 12 h at 723 K. The data analysis showed that 15 % of the methane gas released from hydrates

Microbial community changes with decaying chloramine residuals in a lab-scale system.

PubMed

Bal Krishna, K C; Sathasivan, Arumugam; Ginige, Maneesha P

2013-09-01

When chloramine is used as a disinfectant, managing an acceptable "residual" throughout the water distribution systems particularly once nitrification has set in is challenging. Managing chloramine decay prior to the onset of nitrification through effective control strategies is important and to-date the strategies developed around nitrification has been ineffective. This study aimed at developing a more holistic knowledge on how decaying chloramine and nitrification metabolites impact microbial communities in chloraminated systems. Five lab-scale reactors (connected in series) were operated to simulate a full-scale chloraminated distribution system. Culture independent techniques (cloning and qPCR) were used to characterise and quantify the mixed microbial communities in reactors maintaining a residual of high to low (2.18-0.03 mg/L). The study for the first time associates chloramine residuals and nitrification metabolites to different microbial communities. Bacterial classes Solibacteres, Nitrospira, Sphingobacteria and Betaproteobacteria dominated at low chloramine residuals whereas Actinobacteria and Gammaproteobacteria dominated at higher chloramine residuals. Prior to the onset of nitrification bacterial genera Pseudomonas, Methylobacterium and Sphingomonas were found to be dominant and Sphingomonas in particular increased with the onset of nitrification. Nitrosomonas urea, oligotropha, and two other novel ammonia-oxidizing bacteria were detected once the chloramine residuals had dropped below 0.65 mg/L. Additionally nitrification alone failed to explain chloramine decay rates observed in these reactors. The finding of this study is expected to re-direct the focus from nitrifiers to heterotrophic bacteria, which the authors believe could hold the key towards developing a control strategy that would enable better management of chloramine residuals. Copyright © 2013 Elsevier Ltd. All rights reserved.

Experimental characterization of an adaptive aileron: lab tests and FE correlation

NASA Astrophysics Data System (ADS)

Amendola, Gianluca; Dimino, Ignazio; Amoroso, Francesco; Pecora, Rosario

2016-04-01

Like any other technology, morphing has to demonstrate system level performance benefits prior to implementation onto a real aircraft. The current status of morphing structures research efforts (as the ones, sponsored by the European Union) involves the design of several subsystems which have to be individually tested in order to consolidate their general performance in view of the final integration into a flyable device. This requires a fundamental understanding of the interaction between aerodynamic, structure and control systems. Important worldwide research collaborations were born in order to exchange acquired experience and better investigate innovative technologies devoted to morphing structures. The "Adaptive Aileron" project represents a joint cooperation between Canadian and Italian research centers and leading industries. In this framework, an overview of the design, manufacturing and testing of a variable camber aileron for a regional aircraft is presented. The key enabling technology for the presented morphing aileron is the actuation structural system, integrating a suitable motor and a load-bearing architecture. The paper describes the lab test campaign of the developed device. The implementation of a distributed actuation system fulfills the actual tendency of the aeronautical research to move toward the use of electrical power to supply non-propulsive systems. The aileron design features are validated by targeted experimental tests, demonstrating both its adaptive capability and robustness under operative loads and its dynamic behavior for further aeroelastic analyses. The experimental results show a satisfactory correlation with the numerical expectations thus validating the followed design approach.

Transforming the advanced lab: Part I - Learning goals

NASA Astrophysics Data System (ADS)

Zwickl, Benjamin; Finkelstein, Noah; Lewandowski, H. J.

2012-02-01

Within the physics education research community relatively little attention has been given to laboratory courses, especially at the upper-division undergraduate level. As part of transforming our senior-level Optics and Modern Physics Lab at the University of Colorado Boulder we are developing learning goals, revising curricula, and creating assessments. In this paper, we report on the establishment of our learning goals and a surrounding framework that have emerged from discussions with a wide variety of faculty, from a review of the literature on labs, and from identifying the goals of existing lab courses. Our goals go beyond those of specific physics content and apparatus, allowing instructors to personalize them to their contexts. We report on four broad themes and associated learning goals: Modeling (math-physics-data connection, statistical error analysis, systematic error, modeling of engineered "black boxes"), Design (of experiments, apparatus, programs, troubleshooting), Communication, and Technical Lab Skills (computer-aided data analysis, LabVIEW, test and measurement equipment).

Lab-On-a-Chip Application Development (LOCAD): Bridging Technology Readiness for Exploration

NASA Technical Reports Server (NTRS)

Spearing, Scott F.; Jenkins, Andy

2004-01-01

At Marshall Space Flight Center we have established a capability to investigate the use of microfluidics for space flight. The Lab-On-a-Chip Application Development (LOCAD) team has created a program for advancing Technology Readiness Levels (TRL) of 1 and 2 to TRL 6 and 7, quickly and economically for Lab-On-a-Chip (LOC) applications. Scientists and engineers can utilize LOCAD'S process to efficiently learn about microfluidics and determine if microfluidics is applicable to their needs. Once the applicability has been determined, LOCAD can then perform tests to develop the new fluidic protocols which are different from macro-scale chemical reaction protocols. With this information new micro-fluidic devices can be created and tested. Currently, LOCAD is focused on using microfluidics for both Environmental Monitoring & Control, and Medical Systems. Eventually, handheld portable units utilizing LOC technology will perform rapid tests to determine water quality, and microbial contamination levels. Since LOC technology is drastically reduced in physical size, it thereby reduces power, weight, volume, and sample requirements, a big advantage considering the resource constraints associated with spaceflight. Another one of LOCAD's current activities is the development of a microfluidic system to aid in the search for life on Mars.

Science Labs: Beyond Isolationism

ERIC Educational Resources Information Center

Cavanagh, Sean

2007-01-01

A national study released in 2005 concluded that most high school students are not exposed to high quality science labs because of these reasons: (a) poor school facilities and organizations; (b) weak teacher preparation; (c) poor design; (d) cluttered state standards; (e) little representation on state tests; and (f) scarce evidence of what…

Gap Test Calibrations and Their Scaling

NASA Astrophysics Data System (ADS)

Sandusky, Harold

2011-06-01

Common tests for measuring the threshold for shock initiation are the NOL large scale gap test (LSGT) with a 50.8-mm diameter donor/gap and the expanded large scale gap test (ELSGT) with a 95.3-mm diameter donor/gap. Despite the same specifications for the explosive donor and polymethyl methacrylate (PMMA) gap in both tests, calibration of shock pressure in the gap versus distance from the donor scales by a factor of 1.75, not the 1.875 difference in their sizes. Recently reported model calculations suggest that the scaling discrepancy results from the viscoelastic properties of PMMA in combination with different methods for obtaining shock pressure. This is supported by the consistent scaling of these donors when calibrated in water-filled aquariums. Calibrations with water gaps will be provided and compared with PMMA gaps. Scaling for other donor systems will also be provided. Shock initiation data with water gaps will be reviewed.

Multilayer based lab-on-a-chip-systems for substance testing

NASA Astrophysics Data System (ADS)

Sonntag, Frank; Grünzner, Stefan; Schmieder, Florian; Busek, Mathias; Klotzbach, Udo; Franke, Volker

2015-03-01

An integrated technology chain for laser-microstructuring and bonding of polymer foils for fast, flexible and low-cost manufacturing of multilayer lab-on-a-chip devices especially for complex cell and tissue culture applications, which provides pulsatile fluid flow within physiological ranges at low media-to-cells ratio, was developed and established. Initially the microfluidic system is constructively divided into individual layers which are formed by separate foils or plates. Based on the functional boundary conditions and the necessary properties of each layer the corresponding foils and plates are chosen. In the third step the foils and plates are laser microstructured and functionalized from both sides. In the fourth and last manufacturing step the multiple plates and foils are joined using thermal diffusion bonding. Membranes for pneumatically driven valves and micropumps where bonded via chemical surface modification. Based on the established lab-on-a-chip platform for perfused cell-based assays, a multilayer microfluidic system with two parallel connected cell culture chambers was successfully implemented.

Removal of selected emerging PPCP compounds using greater duckweed (Spirodela polyrhiza) based lab-scale free water constructed wetland.

PubMed

Li, Jianan; Zhou, Qizhi; Campos, Luiza C

2017-12-01

Greater duckweed (Spirodela polyrhiza) based lab-scale free water constructed wetland (CW) was employed for removing four emerging pharmaceuticals and personal care products (PPCPs) (i.e. DEET, paracetamol, caffeine and triclosan). Orthogonal design was used to test the effect of light intensity, aeration, E.coli abundance and plant biomass on the target compounds. Synthetic wastewater contaminated with the target compounds at concentration of 25 μg/L was prepared, and both batch and continuous flow experiments were conducted. Up to 100% removals were achieved for paracetamol (PAR), caffeine (CAF) and tricolsan (TCS) while the highest removal for DEET was 32.2% in batch tests. Based on orthogonal Duncan analysis, high light intensity (240 μmolmm -2 s -1 ), full aeration, high plant biomass (1.00 kg/m 2 ) and high E.coli abundance (1.0 × 10 6  CFU/100 mL) favoured elimination of the PPCPs. Batch verification test achieved removals of 17.1%, 98.8%, 96.4% and 95.4% for DEET, PAR, CAF and TCS respectively. Continuous flow tests with CW only and CW followed by stabilization tank (CW-ST) were carried out. Final removals of the PPCP contaminants were 32.6%, 97.7%, 98.0% and 100% for DEET, PAR, CAF and TCS, respectively, by CW system alone, while 43.3%, 97.5%, 98.2% and 100%, respectively, were achieved by CW-ST system. By adding the ST tank, PPCP concentrations decreased significantly faster (p < 0.05) compared with continuous flow CW alone. In addition, after removing aerators during continuous flow CW experiments, the treatment systems presented good stability for the PPCP removals. CW-ST showed better chemical oxygen demand (COD) and total organic carbon (TOC) removals (89.3%, 91.2%, respectively) than CW only (79.4%, 85.2%, respectively). However, poor DEET removal (<50%) and high E.coli abundance (up to 1.7 log increase) in the final treated water indicated further treatment processes may be required. Statistical analysis showed significant correlations

76 FR 18348 - Required Scale Tests

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-04

... RIN 0580-AB10 Required Scale Tests AGENCY: Grain Inspection, Packers and Stockyards Administration... published a document in the Federal Register on January 20, 2011 (76 FR 3485), defining required scale tests...-month period following each test. * * * * * Alan R. Christian, Acting Administrator, Grain Inspection...

Leaching behaviour of incineration bottom ash in a reuse scenario: 12years-field data vs. lab test results.

PubMed

Di Gianfilippo, Martina; Hyks, Jiri; Verginelli, Iason; Costa, Giulia; Hjelmar, Ole; Lombardi, Francesco

2018-03-01

Several types of standardized laboratory leaching tests have been developed during the past few decades to evaluate the leaching behaviour of waste materials as a function of different parameters, such as the pH of the eluate and the liquid to solid ratio. However, the link between the results of these tests and leaching data collected from the field (e.g. in disposal or reuse scenarios) is not always straightforward. In this work, we compare data obtained from an on-going large scale field trial, in which municipal solid waste incineration bottom ash is being tested as road sub-base material, with the results obtained from percolation column and pH-dependence laboratory leaching tests carried out on the bottom ash at the beginning of the test. The comparisons reported in this paper show that for soluble substances (e.g. Cl, K and SO 4 ), percolation column tests can provide a good indication of the release expected in the field with deviations usually within a factor of 3. For metals characterized by a solubility-controlled release, i.e. that depends more on eluate pH than the liquid to solid ratio applied, the results of pH-dependence tests describe more accurately the eluate concentration trends observed in the field with deviations that in most cases (around 80%) are within one order of magnitude (see e.g. Al and Cd). The differences between field and lab-scale data might be in part ascribed to the occurrence in the field of weathering reactions (e.g. carbonation) but also to microbial decomposition of organic matter that modifying leachate pH affect the solubility of several constituents (e.g. Ca, Ba and Cr). Besides, weathering reactions can result in enhanced adsorption of fulvic acids to iron/aluminum (hydr)oxides, leading to a decrease in the leaching of fulvic acids and hence of elements such as Cu, Ni and Pb that strongly depend on DOC leaching. Overall, this comparison shows that percolation column tests and pH-dependence tests can represent a reliable

e-Learning - Physics Labs

NASA Astrophysics Data System (ADS)

Mohottala, Hashini

2014-03-01

The general student population enrolled in any college level class is highly diverse. An increasing number of ``nontraditional'' students return to college and most of these students follow distance learning degree programs while engaging in their other commitments, work and family. However, those students tend to avoid taking science courses with labs, mostly because of the incapability of remotely completing the lab components in such courses. In order to address this issue, we have come across a method where introductory level physics labs can be taught remotely. In this process a lab kit with the critical lab components that can be easily accessible are conveniently packed into a box and distributed among students at the beginning of the semester. Once the students are given the apparatus they perform the experiments at home and gather data All communications with reference to the lab was done through an interactive user-friendly webpage - Wikispaces (WikiS). Students who create pages on WikiS can submit their lab write-ups, embed videos of the experiments they perform, post pictures and direct questions to the lab instructor. The students who are enrolled in the same lab can interact with each other through WikiS to discuss labs and even get assistance.

Successes and Challenges in Transitioning to Large Enrollment NEXUS/Physics IPLS Labs

NASA Astrophysics Data System (ADS)

Moore, Kimberly

2017-01-01

UMd-PERG's NEXUS/Physics for Life Sciences laboratory curriculum, piloted in 2012-2013 in small test classes, has been implemented in large-enrollment environments at UMD from 2013-present. These labs address physical issues at biological scales using microscopy, image and video analysis, electrophoresis, and spectroscopy in an open, non-protocol-driven environment. We have collected a wealth of data (surveys, video analysis, etc.) that enables us to get a sense of the students' responses to this curriculum in a large-enrollment environment and with teaching assistants both `new to' and `experienced in' the labs. In this talk, we will provide a brief overview of what we have learned, including the challenges of transitioning to large N, student perception then and now, and comparisons of our large-enrollment results to the results from our pilot study. We will close with a discussion of the acculturation of teaching assistants to this novel environment and suggestions for sustainability.

Innovative Use of a Classroom Response System During Physics Lab

NASA Astrophysics Data System (ADS)

Walgren, Jay

2011-01-01

More and more physics instructors are making use of personal/classroom response systems or "clickers." The use of clickers to engage students with multiple-choice questions during lecture and available instructor resources for clickers have been well documented in this journal.1-4 Newer-generation clickers, which I refer to as classroom response systems (CRS), have evolved to accept numeric answers (such as 9.81) instead of just single "multiple-choice" entries (Fig. 1). This advancement is available from most major clicker companies and allows for a greater variety of engaging questions during lecture. In addition, these new "numeric ready" clickers are marketed to be used for student assessments. During a test or quiz, students' answers are entered into their clicker instead of on paper or Scantron® and immediately absorbed by wireless connection into a computer for grading and analysis. I recognize the usefulness and benefit these new-generation CRSs provide for many instructors. However, I do not use my CRS in either of the aforementioned activities. Instead, I use it in an unconventional way. I use the CRS to electronically capture students' lab data as they are performing a physics lab (Fig. 2). I set up the clickers as if I were going to use them for a test, but instead of entering answers to a test, my students enter lab data as they collect it. In this paper I discuss my use of a classroom response system during physics laboratory and three benefits that result: 1) Students are encouraged to "take ownership of" and "have integrity with" their physics lab data. 2) Students' measuring and unit conversion deficiencies are identified immediately during the lab. 3) The process of grading students' labs is simplified because the results of each student's lab calculations can be pre-calculated for the instructor using a spreadsheet. My use of clickers during lab can be implemented with most clicker systems available to instructors today. The CRS I use is the e

Engineering-Scale Demonstration of DuraLith and Ceramicrete Waste Forms

DOE Office of Scientific and Technical Information (OSTI.GOV)

Josephson, Gary B.; Westsik, Joseph H.; Pires, Richard P.

2011-09-23

To support the selection of a waste form for the liquid secondary wastes from the Hanford Waste Immobilization and Treatment Plant, Washington River Protection Solutions (WRPS) has initiated secondary waste form testing on four candidate waste forms. Two of the candidate waste forms have not been developed to scale as the more mature waste forms. This work describes engineering-scale demonstrations conducted on Ceramicrete and DuraLith candidate waste forms. Both candidate waste forms were successfully demonstrated at an engineering scale. A preliminary conceptual design could be prepared for full-scale production of the candidate waste forms. However, both waste forms are stillmore » too immature to support a detailed design. Formulations for each candidate waste form need to be developed so that the material has a longer working time after mixing the liquid and solid constituents together. Formulations optimized based on previous lab studies did not have sufficient working time to support large-scale testing. The engineering-scale testing was successfully completed using modified formulations. Further lab development and parametric studies are needed to optimize formulations with adequate working time and assess the effects of changes in raw materials and process parameters on the final product performance. Studies on effects of mixing intensity on the initial set time of the waste forms are also needed.« less

Symbiotic relationship analysis of predominant bacteria in a lab-scale anammox UASB bioreactor.

PubMed

Wang, Yujia; Hu, Xiaomin; Jiang, Binhui; Song, Zhenhui; Ma, Yongguang

2016-04-01

In order to provide the comprehensive insight into the key microbial groups in anaerobic ammonium oxidation (anammox) process, high-throughput sequencing analysis has been used for the investigation of the bacterial communities of a lab-scale upflow anaerobic sludge bed (UASB) anammox bioreactor. Results revealed that 109 operational taxonomic units (OTUs; out of 14,820 reads) were identified and a domination of anammox bacteria of Candidatus Kuenenia stuttgartiensis (OTU474, 35.42 %), along with heterotrophs of Limnobacter sp. MED105 (OTU951, 14.98 %), Anerolinea thermophila UNI-1 (OTU465 and OTU833, 6.60 and 3.93 %), Azoarcus sp. B72 (OTU26, 9.47 %), and Ignavibacterium sp. JCM 16511 (OTU459, 8.33 %) were detected. Metabolic pathway analysis showed that Candidatus K. stuttgartiensis encountered gene defect in synthesizing a series of metabolic cofactors for growth, implying that K. stuttgartiensis is auxotrophic. Coincidentally, the other dominant species severally showed complete metabolic pathways with full set gene encoding to corresponding cofactors presented in the surrounding environment. Furthermore, it was likely that the survival of heterotrophs in the autotrophic system indicates the existence of a symbiotic and mutual relationship in anammox system.

Lab-scale demonstration of recuperative thickening technology for enhanced biogas production and dewaterability in anaerobic digestion processes.

PubMed

Cobbledick, Jeffrey; Aubry, Nicholas; Zhang, Victor; Rollings-Scattergood, Sasha; Latulippe, David R

2016-05-15

There is growing interest in the use of high performance anaerobic digestion (AD) processes for the production of biogas at wastewater treatment facilities to offset the energy demands associated with wastewater treatment. Recuperative thickening (RT) is a promising technique which involves recycling a portion of the digested solids back to the incoming feed. In general there exists a significant number of knowledge gaps in the field of RT because the studies that have been conducted to date have almost exclusively occurred in pilot plant or full scale trials; this approach greatly limits the amount of process optimization that can be done in a given trial. In this work, a detailed and comprehensive study of RT was conducted at the lab scale; two custom designed digesters (capacity = 1.5 L) were operated in parallel with one acting as a 'control' digester and the other operating under a semi-batch RT mode. There was no significant change in biogas methane composition for the two digesters, however the RT digester had an average biogas productivity over two times higher than the control one. It was found that the recycling of the polymer flocculant back into the RT digester resulted in a significant improvement in dewatering performance. At the highest polymer concentration tested, the capillary suction time (CST) values for flocculated samples for the RT digester were over 6 times lower than the corresponding values for the control digester. Thus, there exists an opportunity to decrease the overall consumption of polymer flocculants through judicious selection of the dose of polymer flocculant that is used both for the thickening and end-stage dewatering steps in RT processes. Copyright © 2016 Elsevier Ltd. All rights reserved.

Development and integration of a LabVIEW-based modular architecture for automated execution of electrochemical catalyst testing.

PubMed

Topalov, Angel A; Katsounaros, Ioannis; Meier, Josef C; Klemm, Sebastian O; Mayrhofer, Karl J J

2011-11-01

This paper describes a system for performing electrochemical catalyst testing where all hardware components are controlled simultaneously using a single LabVIEW-based software application. The software that we developed can be operated in both manual mode for exploratory investigations and automatic mode for routine measurements, by using predefined execution procedures. The latter enables the execution of high-throughput or combinatorial investigations, which decrease substantially the time and cost for catalyst testing. The software was constructed using a modular architecture which simplifies the modification or extension of the system, depending on future needs. The system was tested by performing stability tests of commercial fuel cell electrocatalysts, and the advantages of the developed system are discussed. © 2011 American Institute of Physics

Cyberinfrastructure to Support Collaborative Research Within Small Ecology Labs

NASA Astrophysics Data System (ADS)

Laney, C.; Jaimes, A.; Cody, R. P.; Kassin, A.; Salayandia, L.; Tweedie, C. E.

2011-12-01

Increasingly, ecological research programs addressing complex challenges are driving technological innovations that allow the acquisition and analysis of data collected over larger spatial scales and finer temporal resolutions. Many research labs are shifting from deploying technicians or students into the field to setting up automated sensors. These sensors can cost less on an individual basis, provide continuous and reliable data collection, and allow researchers to spend more time analyzing data and testing hypotheses. They can provide an enormous amount of complex information about an ecosystem. However, the effort to manage, analyze, and disseminate that information can be daunting. Small labs unfamiliar with these efforts may find their capacity to publish at competitive rates hindered by information management. Such labs would be well served by an easy to manage cyberinfrastructure (CI) that is organized in a modular, plug-and-play design and is amenable to a wide variety of data types. Its functionality would permit addition of new sensors and perform automated data analysis and visualization. Such a system would conceivably enhance access to data from small labs through web services, thereby improving the representation of smaller labs in scientific syntheses and enhancing the spatial and temporal coverage of such efforts. We present a CI that is designed to meet the needs of a small but heavily instrumented research site located within the USDA ARS Jornada Experimental Range in the northern Chihuahuan Desert. This site was constructed and is operated by the Systems Ecology Lab at the University of Texas at El Paso (UTEP), a relatively small and young lab. Researchers at the site study land-atmosphere carbon, water, and energy fluxes at a mixed creosote (Larrea tridentata) - mesquite (Prosopis glandulosa) shrubland. The site includes an eddy covariance tower built to AmeriFlux and FLUXNET specifications, a robotic cart that measures hyperspectral

Assessment of human epidermal model LabCyte EPI-MODEL for in vitro skin irritation testing according to European Centre for the Validation of Alternative Methods (ECVAM)-validated protocol.

PubMed

Katoh, Masakazu; Hamajima, Fumiyasu; Ogasawara, Takahiro; Hata, Ken-Ichiro

2009-06-01

A validation study of an in vitro skin irritation testing method using a reconstructed human skin model has been conducted by the European Centre for the Validation of Alternative Methods (ECVAM), and a protocol using EpiSkin (SkinEthic, France) has been approved. The structural and performance criteria of skin models for testing are defined in the ECVAM Performance Standards announced along with the approval. We have performed several evaluations of the new reconstructed human epidermal model LabCyte EPI-MODEL, and confirmed that it is applicable to skin irritation testing as defined in the ECVAM Performance Standards. We selected 19 materials (nine irritants and ten non-irritants) available in Japan as test chemicals among the 20 reference chemicals described in the ECVAM Performance Standard. A test chemical was applied to the surface of the LabCyte EPI-MODEL for 15 min, after which it was completely removed and the model then post-incubated for 42 hr. Cell v iability was measured by MTT assay and skin irritancy of the test chemical evaluated. In addition, interleukin-1 alpha (IL-1alpha) concentration in the culture supernatant after post-incubation was measured to provide a complementary evaluation of skin irritation. Evaluation of the 19 test chemicals resulted in 79% accuracy, 78% sensitivity and 80% specificity, confirming that the in vitro skin irritancy of the LabCyte EPI-MODEL correlates highly with in vivo skin irritation. These results suggest that LabCyte EPI-MODEL is applicable to the skin irritation testing protocol set out in the ECVAM Performance Standards.

Evaluation of oral microbiology lab curriculum reform.

PubMed

Nie, Min; Gao, Zhen Y; Wu, Xin Y; Jiang, Chen X; Du, Jia H

2015-12-07

According to the updated concept of oral microbiology, the School of Stomatology, Wuhan University, has carried out oral microbiology teaching reforms during the last 5 years. There was no lab curriculum before 2009 except for a theory course of oral microbiology. The school has implemented an innovative curriculum with oral medicine characteristics to strengthen understanding of knowledge, cultivate students' scientific interest and develop their potential, to cultivate the comprehensive ability of students. This study was designed to evaluate the oral microbiology lab curriculum by analyzing student performance and perceptions regarding the curriculum from 2009 to 2013. The lab curriculum adopted modalities for cooperative learning. Students collected dental plaque from each other and isolated the cariogenic bacteria with selective medium plates. Then they purified the enrichment culture medium and identified the cariogenic strains by Gram stain and biochemical tests. Both quantitative and qualitative data for 5 years were analysed in this study. Part One of the current study assessed student performance in the lab from 2009 to 2013. Part Two used qualitative means to assess students' perceptions by an open questionnaire. The 271 study students' grades on oral microbiology improved during the lab curriculum: "A" grades rose from 60.5 to 81.2 %, and "C" grades fell from 28.4 to 6.3 %. All students considered the lab curriculum to be interesting and helpful. Quantitative and qualitative data converge to suggest that the lab curriculum has strengthened students' grasp of important microbiology-related theory, cultivated their scientific interest, and developed their potential and comprehensive abilities. Our student performance and perception data support the continued use of the innovative teaching system. As an extension and complement of the theory course, the oral microbiology lab curriculum appears to improve the quality of oral medicine education and help to

Differences between Lab Completion and Non-Completion on Student Performance in an Online Undergraduate Environmental Science Program

NASA Astrophysics Data System (ADS)

Corsi, Gianluca

2011-12-01

Web-based technology has revolutionized the way education is delivered. Although the advantages of online learning appeal to large numbers of students, some concerns arise. One major concern in online science education is the value that participation in labs has on student performance. The purpose of this study was to assess the relationships between lab completion and student academic success as measured by test grades, scientific self-confidence, scientific skills, and concept mastery. A random sample of 114 volunteer undergraduate students, from an online Environmental Science program at the American Public University System, was tested. The study followed a quantitative, non-experimental research design. Paired sample t-tests were used for statistical comparison between pre-lab and post-lab test grades, two scientific skills quizzes, and two scientific self-confidence surveys administered at the beginning and at the end of the course. The results of the paired sample t-tests revealed statistically significant improvements on all post-lab test scores: Air Pollution lab, t(112) = 6.759, p < .001; Home Chemicals lab t(114) = 8.585, p < .001; Water Use lab, t(116) = 6.657, p < .001; Trees and Carbon lab, t(113) = 9.921, p < .001; Stratospheric Ozone lab, t(112) =12.974, p < .001; Renewable Energy lab, t(115) = 7.369, p < .001. The end of the course Scientific Skills quiz revealed statistically significant improvements, t(112) = 8.221, p < .001. The results of the two surveys showed a statistically significant improvement on student Scientific Self-Confidence because of lab completion, t(114) = 3.015, p < .05. Because age and gender were available, regression models were developed. The results indicated weak multiple correlation coefficients and were not statistically significant at alpha = .05. Evidence suggests that labs play a positive role in a student's academic success. It is recommended that lab experiences be included in all online Environmental Science

Investigation of lab-scale horizontal subsurface flow constructed wetlands treating industrial cork boiling wastewater.

PubMed

Gomes, Arlindo C; Silva, Lúcia; Albuquerque, António; Simões, Rogério; Stefanakis, Alexandros I

2018-09-01

The feasibility and treatment efficiency of horizontal subsurface flow constructed wetlands (HSFCW) was assessed for the first time for cork boiling wastewater (CBW) through laboratory experiments. CBW is known for its high content of phenolic compounds, complex composition of biorecalcitrant and toxic nature. Two lab-scale units, one planted with Phragmites australis (CWP) and one unplanted (CWC), were used to evaluate the removals of COD, BOD, total phenolic compounds (TPh) and decolourization over a 2.5-years monitoring period under Mediterranean climatic conditions. Seven organic and hydraulic loading rates ranging from 2.6 to 11.5 g COD/m 2 /d and 5.7-9.1 L/m 2 /d were tested under average hydraulic retention time (HRT) of 5 ± 1 days required due to the CWB limited biodegradability (i.e., BOD 5 /COD of 0.19). Average removals of the CWP exceeded those of the CWC and reached 74.6%, 91.7% and 69.1% for COD, BOD 5 and TPh, respectively, with respective mass removals rates up to 7.0, 1.7 and 0.5 (in g/m 2 /d). Decolourization was limited to 35%, since it mainly depends on physical processes rather than biodegradation. CBW concentration of nine phenolic compounds ranged from 1.2 to 38.4 mg/L (for the syringic and ellagic acids, respectively) in the raw CBW, with respective removals in the CWP unit ranging from 41.8 to 76.3%, higher than those in the control unit. Despite CBW high concentration of TPhs (average of 116.3 mg/L), the HSFCW reached organic load removals higher than those of conventional biological treatment methods. Copyright © 2018 Elsevier Ltd. All rights reserved.

A Comparative Study on Real Lab and Simulation Lab in Communication Engineering from Students' Perspectives

ERIC Educational Resources Information Center

Balakrishnan, B.; Woods, P. C.

2013-01-01

Over the years, rapid development in computer technology has engendered simulation-based laboratory (lab) in addition to the traditional hands-on (physical) lab. Many higher education institutions adopt simulation lab, replacing some existing physical lab experiments. The creation of new systems for conducting engineering lab activities has raised…

Kinematic Labs with Mobile Devices

NASA Astrophysics Data System (ADS)

Kinser, Jason M.

2015-07-01

This book provides 13 labs spanning the common topics in the first semester of university-level physics. Each lab is designed to use only the student's smartphone, laptop and items easily found in big-box stores or a hobby shop. Each lab contains theory, set-up instructions and basic analysis techniques. All of these labs can be performed outside of the traditional university lab setting and initial costs averaging less than 8 per student, per lab.

Teachers' Perspectives on Online Virtual Labs vs. Hands-On Labs in High School Science

NASA Astrophysics Data System (ADS)

Bohr, Teresa M.

This study of online science teachers' opinions addressed the use of virtual labs in online courses. A growing number of schools use virtual labs that must meet mandated laboratory standards to ensure they provide learning experiences comparable to hands-on labs, which are an integral part of science curricula. The purpose of this qualitative case study was to examine teachers' perceptions of the quality and effectiveness of high school virtual labs. The theoretical foundation was constructivism, as labs provide student-centered activities for problem solving, inquiry, and exploration of phenomena. The research questions focused on experienced teachers' perceptions of the quality of virtual vs. hands-on labs. Data were collected through survey questions derived from the lab objectives of The Next Generation Science Standards . Eighteen teachers rated the degree of importance of each objective and also rated how they felt virtual labs met these objectives; these ratings were reported using descriptive statistics. Responses to open-ended questions were few and served to illustrate the numerical results. Many teachers stated that virtual labs are valuable supplements but could not completely replace hands-on experiences. Studies on the quality and effectiveness of high school virtual labs are limited despite widespread use. Comprehensive studies will ensure that online students have equal access to quality labs. School districts need to define lab requirements, and colleges need to specify the lab experience they require. This study has potential to inspire positive social change by assisting science educators, including those in the local school district, in evaluating and selecting courseware designed to promote higher order thinking skills, real-world problem solving, and development of strong inquiry skills, thereby improving science instruction for all high school students.

TangoLab-2 Card Troubleshooting

NASA Image and Video Library

2017-10-17

iss053e105442 (Oct. 17, 2017) --- Flight Engineer Mark Vande Hei swaps out a payload card from the TangoLab-1 facility and places into the TangoLab-2 facility. TangoLab provides a standardized platform and open architecture for experimental modules called CubeLabs. CubeLab modules may be developed for use in 3-dimensional tissue and cell cultures.

Hydraulic fracture conductivity: effects of rod-shaped proppant from lattice-Boltzmann simulations and lab tests

NASA Astrophysics Data System (ADS)

Osiptsov, Andrei A.

2017-06-01

The goal of this study is to evaluate the conductivity of random close packings of non-spherical, rod-shaped proppant particles under the closure stress using numerical simulation and lab tests, with application to the conductivity of hydraulic fractures created in subterranean formation to stimulate production from oil and gas reservoirs. Numerical simulations of a steady viscous flow through proppant packs are carried out using the lattice Boltzmann method for the Darcy flow regime. The particle packings were generated numerically using the sequential deposition method. The simulations are conducted for packings of spheres, ellipsoids, cylinders, and mixtures of spheres with cylinders at various volumetric concentrations. It is demonstrated that cylinders provide the highest permeability among the proppants studied. The dependence of the nondimensional permeability (scaled by the equivalent particle radius squared) on porosity obtained numerically is well approximated by the power-law function: K /Rv2 = 0.204ϕ4.58 in a wide range of porosity: 0.3 ≤ ϕ ≤ 0.7. Lattice-Boltzmann simulations are cross-verified against finite-volume simulations using Navier-Stokes equations for inertial flow regime. Correlations for the normalized beta-factor as a function of porosity and normalized permeability are presented as well. These formulae are in a good agreement with the experimental measurements (including packings of rod-shaped particles) and existing laboratory data, available in the porosity range 0.3 ≤ ϕ ≤ 0.5. Comparison with correlations by other authors is also given.

Comparative analysis of the bacterial diversity in a lab-scale moving bed biofilm reactor (MBBR) applied to treat urban wastewater under different operational conditions.

PubMed

Calderón, Kadiya; Martín-Pascual, Jaime; Poyatos, José Manuel; Rodelas, Belén; González-Martínez, Alejandro; González-López, Jesús

2012-10-01

Different types of carriers were tested as support material in a lab-scale moving bed biofilm reactor (MBBR) used to treat urban wastewater under three different conditions of hydraulic retention time (HRT) and carrier filling ratios (FR). The bacterial diversity developed on the biofilms responsible of the treatment was studied using a cultivation-independent approach based on the polymerase chain reaction-temperature gradient gel electrophoresis technique (PCR-TGGE). Cluster analysis of TGGE fingerprints showed significant differences of community structure dependent upon the different operational conditions applied. Redundancy analysis (RDA) was used to determine the relationship between the operational conditions (type of carrier, HRT, FR) and bacterial biofilm diversity, demonstrating a significant effect of FR=50%. Phylogenetic analysis of PCR-reamplified and sequenced TGGE bands revealed that the prevalent Bacteria populations in the biofilm were related to Betaproteobacteria (46%), Firmicutes (34%),Alphaproteobacteria (14%) and Gammaproteobacteria (9%). Copyright © 2012 Elsevier Ltd. All rights reserved.

A comparative study on real lab and simulation lab in communication engineering from students' perspectives

NASA Astrophysics Data System (ADS)

Balakrishnan, B.; Woods, P. C.

2013-05-01

Over the years, rapid development in computer technology has engendered simulation-based laboratory (lab) in addition to the traditional hands-on (physical) lab. Many higher education institutions adopt simulation lab, replacing some existing physical lab experiments. The creation of new systems for conducting engineering lab activities has raised concerns among educators on the merits and shortcomings of both physical and simulation labs; at the same time, many arguments have been raised on the differences of both labs. Investigating the effectiveness of both labs is complicated, as there are multiple factors that should be considered. In view of this challenge, a study on students' perspectives on their experience related to key aspects on engineering laboratory exercise was conducted. In this study, the Visual Auditory Read and Kinetic model was utilised to measure the students' cognitive styles. The investigation was done through a survey among participants from Multimedia University, Malaysia. The findings revealed that there are significant differences for most of the aspects in physical and simulation labs.

Scaled Rocket Testing in Hypersonic Flow

NASA Technical Reports Server (NTRS)

Dufrene, Aaron; MacLean, Matthew; Carr, Zakary; Parker, Ron; Holden, Michael; Mehta, Manish

2015-01-01

NASA's Space Launch System (SLS) uses four clustered liquid rocket engines along with two solid rocket boosters. The interaction between all six rocket exhaust plumes will produce a complex and severe thermal environment in the base of the vehicle. This work focuses on a recent 2% scale, hot-fire SLS base heating test. These base heating tests are short-duration tests executed with chamber pressures near the full-scale values with gaseous hydrogen/oxygen engines and RSRMV analogous solid propellant motors. The LENS II shock tunnel/Ludwieg tube tunnel was used at or near flight duplicated conditions up to Mach 5. Model development was strongly based on the Space Shuttle base heating tests with several improvements including doubling of the maximum chamber pressures and duplication of freestream conditions. Detailed base heating results are outside of the scope of the current work, rather test methodology and techniques are presented along with broader applicability toward scaled rocket testing in supersonic and hypersonic flow.

Evaluation of Inter-Mountain Labs infrasound sensors : July 2007.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hart, Darren M.

2007-10-01

Sandia National Laboratories has tested and evaluated three Inter Mountain Labs infrasound sensors. The test results included in this report were in response to static and tonal-dynamic input signals. Most test methodologies used were based on IEEE Standards 1057 for Digitizing Waveform Recorders and 1241 for Analog to Digital Converters; others were designed by Sandia specifically for infrasound application evaluation and for supplementary criteria not addressed in the IEEE standards. The objective of this work was to evaluate the overall technical performance of the Inter Mountain Labs (IML) infrasound sensor model SS. The results of this evaluation were only comparedmore » to relevant noise models; due to a lack of manufactures documentation notes on the sensors under test prior to testing. The tests selected for this system were chosen to demonstrate different performance aspects of the components under test.« less

A Constructivist Cloud Lab.

ERIC Educational Resources Information Center

Emery, Dave

1996-01-01

Describes a lab involving a cloud formation activity that uses the constructivist learning model to get students more involved in creating the lab. Enables students to develop a greater understanding of the concepts involved and more interest in the lab's outcomes. (JRH)

Virtual Reality Lab Assistant

NASA Technical Reports Server (NTRS)

Saha, Hrishikesh; Palmer, Timothy A.

1996-01-01

Virtual Reality Lab Assistant (VRLA) demonstration model is aligned for engineering and material science experiments to be performed by undergraduate and graduate students in the course as a pre-lab simulation experience. This will help students to get a preview of how to use the lab equipment and run experiments without using the lab hardware/software equipment. The quality of the time available for laboratory experiments can be significantly improved through the use of virtual reality technology.

GeoLab's First Field Trials, 2010 Desert RATS: Evaluating Tools for Early Sample Characterization

NASA Technical Reports Server (NTRS)

Evans, Cindy A.; Bell, M. S.; Calaway, M. J.; Graff, Trevor; Young, Kelsey

2011-01-01

As part of an accelerated prototyping project to support science operations tests for future exploration missions, we designed and built a geological laboratory, GeoLab, that was integrated into NASA's first generation Habitat Demonstration Unit-1/Pressurized Excursion Module (HDU1-PEM). GeoLab includes a pressurized glovebox for transferring and handling samples collected on geological traverses, and a suite of instruments for collecting preliminary data to help characterize those samples. The GeoLab and the HDU1-PEM were tested for the first time as part of the 2010 Desert Research and Technology Studies (DRATS), NASA's analog field exercise for testing mission technologies. The HDU1- PEM and GeoLab participated in two weeks of joint operations in northern Arizona with two crewed rovers and the DRATS science team.

Observation of Flame Stabilized at a Hydrogen-Turbojet-Engine Injector Installed into a Lab-Scale Combustion Wind Tunnel

NASA Astrophysics Data System (ADS)

Michishita, Kazutaka; Nomura, Hiroshi; Ujiie, Yasushige; Okai, Keiichi

A lab-scale combustion wind tunnel was developed for investigation of low-pressure ignition and flame holding in a sub-scale pre-cooled turbojet engine with hydrogen fuel in order to make engine start at high altitudes sure. The combustion wind tunnel is a blow-down type. A fuel injector of the sub-scale pre-cooled turbojet engine was installed into the combustion wind tunnel. Conditions in which a flame can be stabilized at the fuel injector were examined. The combustor pressure and equivalence ratio were varied from 10 to 40 kPa and from 0.4 to 0.8, respectively. The mean inlet air velocity was varied from 2 to 48 m/s. Flames stabilized at 20 kPa in pressure and 0.6 in equivalence ratio were observed. It was found that the decrease in the combustor pressure narrows the mean inlet air velocity range for successful flame holdings. Flame holding at lower combustor pressures is realized at the equivalence ratio of 0.4 in the low mean inlet air velocity range, and at the equivalence ratio of 0.6 in the high mean inlet air velocity range. Flame luminosity is the largest near the fuel injector. The flame luminosity distribution becomes flatter as the increase in the mean inlet air velocity.

LabSkills

ERIC Educational Resources Information Center

O'Brien, Nick

2010-01-01

This article describes LabSkills, a revolutionary teaching tool to improve practical science in schools. LabSkills offers the chance to help improve the exposure that the average Key Stage 5 (age 16-19) student has to practical work. This is a huge area for development being highlighted by universities who are seeing a worryingly growing trend in…

An update on Lab Rover: A hospital material transporter

NASA Technical Reports Server (NTRS)

Mattaboni, Paul

1994-01-01

The development of a hospital material transporter, 'Lab Rover', is described. Conventional material transport now utilizes people power, push carts, pneumatic tubes and tracked vehicles. Hospitals are faced with enormous pressure to reduce operating costs. Cyberotics, Inc. developed an Autonomous Intelligent Vehicle (AIV). This battery operated service robot was designed specifically for health care institutions. Applications for the AIV include distribution of clinical lab samples, pharmacy drugs, administrative records, x-ray distribution, meal tray delivery, and certain emergency room applications. The first AIV was installed at Lahey Clinic in Burlington, Mass. Lab Rover was beta tested for one year and has been 'on line' for an additional 2 years.

Acceptance Tests for AMS Radiocarbon Measurements at iThemba LABS, Gauteng, South Africa

NASA Astrophysics Data System (ADS)

Mbele, Vela L.; Mullins, Simon M.; Winkler, Stephan R.; Woodborne, Stephan

The accelerator mass spectrometer was commissioned recently at the iThemba LABS 6 MV tandem accelerator. Improvements in the vacuum system, requiring procurement of cryo-pumps and the reducing the tank pressure of the N2 + CO2 insulation gas mixture below the level used for IBA measurements, were necessary. This resulted in the reduction of the nitrogen background and improved the resolution of 14C from 14N background in the ionisation chamber. The nitrogen was leaking to the stripping canal because of inadequate sealing. The analysing magnet was scaled to detect C3+ ions, at 3 MV terminal potential. The first sensible spectra allowed for the pin-pointing of many persistent issues. This resulted in measurements with a precision better than 1 pMC, and current blank levels correspond to 12 half-lives of 14C or ∼68000 years. The radiocarbon sample preparation laboratory has reached production status. A brief outlook of the work towards the implementation of the measurement and chemical preparation protocols for radionuclides 10Be and 26Al is also summarised in the conclusion

Using lab notebooks to examine students' engagement in modeling in an upper-division electronics lab course

NASA Astrophysics Data System (ADS)

Stanley, Jacob T.; Su, Weifeng; Lewandowski, H. J.

2017-12-01

We demonstrate how students' use of modeling can be examined and assessed using student notebooks collected from an upper-division electronics lab course. The use of models is a ubiquitous practice in undergraduate physics education, but the process of constructing, testing, and refining these models is much less common. We focus our attention on a lab course that has been transformed to engage students in this modeling process during lab activities. The design of the lab activities was guided by a framework that captures the different components of model-based reasoning, called the Modeling Framework for Experimental Physics. We demonstrate how this framework can be used to assess students' written work and to identify how students' model-based reasoning differed from activity to activity. Broadly speaking, we were able to identify the different steps of students' model-based reasoning and assess the completeness of their reasoning. Varying degrees of scaffolding present across the activities had an impact on how thoroughly students would engage in the full modeling process, with more scaffolded activities resulting in more thorough engagement with the process. Finally, we identified that the step in the process with which students had the most difficulty was the comparison between their interpreted data and their model prediction. Students did not use sufficiently sophisticated criteria in evaluating such comparisons, which had the effect of halting the modeling process. This may indicate that in order to engage students further in using model-based reasoning during lab activities, the instructor needs to provide further scaffolding for how students make these types of experimental comparisons. This is an important design consideration for other such courses attempting to incorporate modeling as a learning goal.

LabVIEW Interface for PCI-SpaceWire Interface Card

NASA Technical Reports Server (NTRS)

Lux, James; Loya, Frank; Bachmann, Alex

2005-01-01

This software provides a LabView interface to the NT drivers for the PCISpaceWire card, which is a peripheral component interface (PCI) bus interface that conforms to the IEEE-1355/ SpaceWire standard. As SpaceWire grows in popularity, the ability to use SpaceWire links within LabVIEW will be important to electronic ground support equipment vendors. In addition, there is a need for a high-level LabVIEW interface to the low-level device- driver software supplied with the card. The LabVIEW virtual instrument (VI) provides graphical interfaces to support all (1) SpaceWire link functions, including message handling and routing; (2) monitoring as a passive tap using specialized hardware; and (3) low-level access to satellite mission-control subsystem functions. The software is supplied in a zip file that contains LabVIEW VI files, which provide various functions of the PCI-SpaceWire card, as well as higher-link-level functions. The VIs are suitably named according to the matching function names in the driver manual. A number of test programs also are provided to exercise various functions.

Lab-scale evaluation of aerated burial concept for treatment and emergency disposal of infectious animal carcasses.

PubMed

Koziel, Jacek A; Ahn, Heekwon; Glanville, Thomas D; Frana, Timothy S; van Leeuwen, J Hans; Nguyen, Lam T

2018-06-01

Nearly 55,000 outbreaks of animal disease were reported to the World Animal Health Information Database between 2005 and 2016. To suppress the spread of disease, large numbers of animal mortalities often must be disposed of quickly and are frequently buried on the farm where they were raised. While this method of emergency disposal is fast and relatively inexpensive, it also can have undesirable and lasting impacts (slow decay, concerns about groundwater contamination, pathogens re-emergence, and odor). Following the 2010 foot-and-mouth disease outbreak, the Republic of Korea's National Institute of Animal Science funded research on selected burial alternatives or modifications believed to have potential to reduce undesirable impacts of burial. One such modification involves the injection of air into the liquid degradation products from the 60-70% water from decomposing carcasses in lined burial trenches. Prior to prototype development in the field, a laboratory-scale study of aerated decomposition (AeD) of poultry carcasses was conducted to quantify improvements in time of carcass decomposition, reduction of potential groundwater pollutants in the liquid products of decomposition (since trench liners may ultimately leak), and reduction of odorous VOCs emitted during decomposition. Headspace gases also were monitored to determine the potential for using gaseous biomarkers in the aerated burial trench exhaust stream to monitor completion of the decomposition. Results of the lab-scale experiments show that the mass of chicken carcasses was reduced by 95.0 ± 0.9% within 3 months at mesophilic temperatures (vs. negligible reduction via mesophilic anaerobic digestion typical of trench burial) with concomitant reduction of biochemical oxygen demand (BOD; 99%), volatile suspended solids (VSS; 99%), total suspended solids (TSS; 99%), and total ammonia nitrogen (TAN; 98%) in the liquid digestate. At week #7 BOD and TSS in digestate met the U.S. EPA standards for

Large-Scale Hybrid Motor Testing. Chapter 10

NASA Technical Reports Server (NTRS)

Story, George

2006-01-01

Hybrid rocket motors can be successfully demonstrated at a small scale virtually anywhere. There have been many suitcase sized portable test stands assembled for demonstration of hybrids. They show the safety of hybrid rockets to the audiences. These small show motors and small laboratory scale motors can give comparative burn rate data for development of different fuel/oxidizer combinations, however questions that are always asked when hybrids are mentioned for large scale applications are - how do they scale and has it been shown in a large motor? To answer those questions, large scale motor testing is required to verify the hybrid motor at its true size. The necessity to conduct large-scale hybrid rocket motor tests to validate the burn rate from the small motors to application size has been documented in several place^'^^.^. Comparison of small scale hybrid data to that of larger scale data indicates that the fuel burn rate goes down with increasing port size, even with the same oxidizer flux. This trend holds for conventional hybrid motors with forward oxidizer injection and HTPB based fuels. While the reason this is occurring would make a great paper or study or thesis, it is not thoroughly understood at this time. Potential causes include the fact that since hybrid combustion is boundary layer driven, the larger port sizes reduce the interaction (radiation, mixing and heat transfer) from the core region of the port. This chapter focuses on some of the large, prototype sized testing of hybrid motors. The largest motors tested have been AMROC s 250K-lbf thrust motor at Edwards Air Force Base and the Hybrid Propulsion Demonstration Program s 250K-lbf thrust motor at Stennis Space Center. Numerous smaller tests were performed to support the burn rate, stability and scaling concepts that went into the development of those large motors.

The national labs and their future

DOE Office of Scientific and Technical Information (OSTI.GOV)

Crease, R.P.

National laboratories of the USA, born with the atomic age and raised to prominence by the need for scientific superiority during the long Cold War, are facing the most critical challenge: how best to support the nation's current need to improve its international competitiveness through superior technology The charge that the national laboratories are [open quotes]Cold War relics[close quotes] that have outlived their usefulness is based on a misunderstanding of their mission, says Robert P. Crease, historian for Brookhaven National laboratory. Three of the labs-Los Alamos, Sandia, and Lawrence Livermore- are weapons laboratories and their missions must change. Oak Ridge,more » Argonne, and Brookhaven laboratories are multipurpose: basic research facilities with a continuing role in the world of science The national laboratory system traces its origins to the Manhattan Project. Over the next half-century, America's national labs grew into part of the most effective scientific establishment in the world, a much-copied model for management of large-scale scientific programs. In the early years, each lab defined a niche in the complex world of reactors, accelerators, and high-energy proton and electron physics. In the 1970s, several labs worked on basic energy sciences to help solve a national energy crisis. Today, the labs are pressured to do more applied research-research to transfer to the private sector and will have to respond by devising more effective ways of coordinating basic and applied research. But, Crease warns, [open quotes]It also will be essential that any commitment to applied research not take place at the cost of reducing the wellspring of basic research from which so much applied research flows. [open quotes]Making a solid and persuasive case for the independent value of basic research, and for their own role in that enterprise, may be the most important task facing the laboratories in their next half-century,[close quotes].« less

Unit Price Scaling Trends for Chemical Products

DOE Office of Scientific and Technical Information (OSTI.GOV)

Qi, Wei; Sathre, Roger; William R. Morrow, III

2015-08-01

To facilitate early-stage life-cycle techno-economic modeling of emerging technologies, here we identify scaling relations between unit price and sales quantity for a variety of chemical products of three categories - metal salts, organic compounds, and solvents. We collect price quotations for lab-scale and bulk purchases of chemicals from both U.S. and Chinese suppliers. We apply a log-log linear regression model to estimate the price discount effect. Using the median discount factor of each category, one can infer bulk prices of products for which only lab-scale prices are available. We conduct out-of-sample tests showing that most of the price proxies deviatemore » from their actual reference prices by a factor less than ten. We also apply the bootstrap method to determine if a sample median discount factor should be accepted for price approximation. We find that appropriate discount factors for metal salts and for solvents are both -0.56, while that for organic compounds is -0.67 and is less representative due to greater extent of product heterogeneity within this category.« less

CESIUM REMOVAL FROM TANKS 241-AN-103 & 241-SX-105 & 241-AZ-101/102 COMPOSITE FOR TESTING IN BENCH SCALE STEAM REFORMER

DOE Office of Scientific and Technical Information (OSTI.GOV)

DUNCAN JB; HUBER HJ

2011-06-08

This report documents the preparation of three actual Hanford tank waste samples for shipment to the Savannah River National Laboratory (SRNL). Two of the samples were dissolved saltcakes from tank 241-AN-103 (hereafter AN-103) and tank 241-SX-105 (hereafter SX-105); one sample was a supernate composite from tanks 241-AZ-101 and 241-AZ-102 (hereafter AZ-101/102). The preparation of the samples was executed following the test plans LAB-PLAN-10-00006, Test Plan for the Preparation of Samples from Hanford Tanks 241-SX-105, 241-AN-103, 241-AN-107, and LAB-PLN-10-00014, Test Plan for the Preparation of a Composite Sample from Hanford Tanks 241-AZ-101 and 241-AZ-102 for Steam Reformer Testing at the Savannahmore » River National Laboratory. All procedural steps were recorded in laboratory notebook HNF-N-274 3. Sample breakdown diagrams for AN-103 and SX-105 are presented in Appendix A. The tank samples were prepared in support of a series of treatability studies of the Fluidized Bed Steam Reforming (FBSR) process using a Bench-Scale Reformer (BSR) at SRNL. Tests with simulants have shown that the FBSR mineralized waste form is comparable to low-activity waste glass with respect to environmental durability (WSRC-STI-2008-00268, Mineralization of Radioactive Wastes by Fluidized Bed Steam Reforming (FBSR): Comparisons to Vitreous Waste Forms and Pertinent Durability Testing). However, a rigorous assessment requires long-term performance data from FB SR product formed from actual Hanford tank waste. Washington River Protection Solutions, LLC (WRPS) has initiated a Waste Form Qualification Program (WP-S.2.1-20 1 0-00 1, Fluidized Bed Steam Reformer Low-level Waste Form Qualification) to gather the data required to demonstrate that an adequate FBSR mineralized waste form can be produced. The documentation of the selection process of the three tank samples has been separately reported in RPP-48824, 'Sample Selection Process for Bench-Scale Steam Reforming Treatability Studies

Sustainable dual-use labs: neurovascular interventional capabilities within the cath lab.

PubMed

Lang, Stacey

2012-01-01

The inclusion of neurovascular interventional capabilities within the cath lab setting can be key to optimal utilization of resources, increased staff efficiency, and streamlined operations. When considering an expansion, look beyond the patient population traditionally associated with cardiac cath labs and consider the integration of programs outside cardiac alone--to create a true dual-use lab space. With proper planning, quality dual purpose equipment, appropriately trained staff, capable physicians, and strong leadership, an organization willing to embrace the challenge can build a truly extraordinary service.

Full scale tank car coupler impact tests

DOT National Transportation Integrated Search

2003-11-15

Full scale tests were performed to investigate various : aspects of tank car behavior during coupler impacts. A tank car : was equipped with 37 accelerometers and an instrumented : coupler. Two series of full scale coupler impact tests, : comprising ...

Lab at Home: Hardware Kits for a Digital Design Lab

ERIC Educational Resources Information Center

Oliver, J. P.; Haim, F.

2009-01-01

An innovative laboratory methodology for an introductory digital design course is presented. Instead of having traditional lab experiences, where students have to come to school classrooms, a "lab at home" concept is proposed. Students perform real experiments in their own homes, using hardware kits specially developed for this purpose. They…

Blood Count Tests - Multiple Languages

MedlinePlus

... window. Arabic (العربية) Expand Section Your Lab Tests - English PDF Your Lab Tests - العربية (Arabic) PDF American ... Cantonese dialect) (繁體中文) Expand Section Your Lab Tests - English PDF Your Lab Tests - 繁體中文 (Chinese, Traditional (Cantonese ...

Institutional profile: the national Swedish academic drug discovery & development platform at SciLifeLab

PubMed Central

Arvidsson, Per I; Sandberg, Kristian; Sakariassen, Kjell S

2017-01-01

The Science for Life Laboratory Drug Discovery and Development Platform (SciLifeLab DDD) was established in Stockholm and Uppsala, Sweden, in 2014. It is one of ten platforms of the Swedish national SciLifeLab which support projects run by Swedish academic researchers with large-scale technologies for molecular biosciences with a focus on health and environment. SciLifeLab was created by the coordinated effort of four universities in Stockholm and Uppsala: Stockholm University, Karolinska Institutet, KTH Royal Institute of Technology and Uppsala University, and has recently expanded to other Swedish university locations. The primary goal of the SciLifeLab DDD is to support selected academic discovery and development research projects with tools and resources to discover novel lead therapeutics, either molecules or human antibodies. Intellectual property developed with the help of SciLifeLab DDD is wholly owned by the academic research group. The bulk of SciLifeLab DDD's research and service activities are funded from the Swedish state, with only consumables paid by the academic research group through individual grants. PMID:28670468

Institutional profile: the national Swedish academic drug discovery & development platform at SciLifeLab.

PubMed

Arvidsson, Per I; Sandberg, Kristian; Sakariassen, Kjell S

2017-06-01

The Science for Life Laboratory Drug Discovery and Development Platform (SciLifeLab DDD) was established in Stockholm and Uppsala, Sweden, in 2014. It is one of ten platforms of the Swedish national SciLifeLab which support projects run by Swedish academic researchers with large-scale technologies for molecular biosciences with a focus on health and environment. SciLifeLab was created by the coordinated effort of four universities in Stockholm and Uppsala: Stockholm University, Karolinska Institutet, KTH Royal Institute of Technology and Uppsala University, and has recently expanded to other Swedish university locations. The primary goal of the SciLifeLab DDD is to support selected academic discovery and development research projects with tools and resources to discover novel lead therapeutics, either molecules or human antibodies. Intellectual property developed with the help of SciLifeLab DDD is wholly owned by the academic research group. The bulk of SciLifeLab DDD's research and service activities are funded from the Swedish state, with only consumables paid by the academic research group through individual grants.

LCOGT Imaging Lab

NASA Astrophysics Data System (ADS)

Tufts, Joseph R.; Lobdill, Rich; Haldeman, Benjamin J.; Haynes, Rachel; Hawkins, Eric; Burleson, Ben; Jahng, David

2008-07-01

The Las Cumbres Observatory Global Telescope Network (LCOGT) is an ambitious project to build and operate, within 5 years, a worldwide robotic network of 50 0.4, 1, and 2 m telescopes sharing identical instrumentation and optimized for precision photometry of time-varying sources. The telescopes, instrumentation, and software are all developed in house with two 2 m telescopes already installed. The LCOGT Imaging Lab is responsible for assembly and characterization of the network's cameras and instrumentation. In addition to a fully equipped CNC machine shop, two electronics labs, and a future optics lab, the Imaging Lab is designed from the ground up to be a superb environment for bare detectors, precision filters, and assembled instruments. At the heart of the lab is an ISO class 5 cleanroom with full ionization. Surrounding this, the class 7 main lab houses equipment for detector characterization including QE and CTE, and equipment for measuring transmission and reflection of optics. Although the first science cameras installed, two TEC cooled e2v 42-40 deep depletion based units and two CryoTiger cooled Fairchild Imaging CCD486-BI based units, are from outside manufacturers, their 18 position filter wheels and the remainder of the network's science cameras, controllers, and instrumentation will be built in house. Currently being designed, the first generation LCOGT cameras for the network's 1 m telescopes use existing CCD486-BI devices and an in-house controller. Additionally, the controller uses digital signal processing to optimize readout noise vs. speed, and all instrumentation uses embedded microprocessors for communication over ethernet.

Report to Lincoln Labs on TWPAs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dubois, J.; Carosi, G.; Woollett, N.

2017-09-26

This past spring LLNL’s Quantum Sensor’s team received two TWPA amplifiers from Lincoln Labs along with a data-sheet explaining handling, operations and expected performance. Here we will outline some of the initial tests performed on this amplifiers as part of LLNL’s Quantum Sensors Strategic Initiative (QSSI). Initial testing confirmed that both amplifiers worked and provided gain and SNR improvement similar to that called out in the data-sheets provided.

Inexpensive DAQ based physics labs

NASA Astrophysics Data System (ADS)

Lewis, Benjamin; Clark, Shane

2015-11-01

Quality Data Acquisition (DAQ) based physics labs can be designed using microcontrollers and very low cost sensors with minimal lab equipment. A prototype device with several sensors and documentation for a number of DAQ-based labs is showcased. The device connects to a computer through Bluetooth and uses a simple interface to control the DAQ and display real time graphs, storing the data in .txt and .xls formats. A full device including a larger number of sensors combined with software interface and detailed documentation would provide a high quality physics lab education for minimal cost, for instance in high schools lacking lab equipment or students taking online classes. An entire semester’s lab course could be conducted using a single device with a manufacturing cost of under $20.

Measurement of α -particle quenching in LAB based scintillator in independent small-scale experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

von Krosigk, B.; Chen, M.; Hans, S.

2016-02-29

The α -particle light response of liquid scintillators based on linear alkylbenzene (LAB) has been measured with three different experimental approaches. In the first approach, α -particles were produced in the scintillator via 12C(n,α) 9 Be reactions. In the second approach, the scintillator was loaded with 2 % of natSm providing an α-emitter, 147Sm, as an internal source. In the third approach, a scintillator flask was deployed into the water-filled SNO+ detector and the radioactive contaminants 222Rn, 218Po and 214Po provided the α -particle signal. The behavior of the observed α -particle light outputs are in agreement with each casemore » successfully described by Birks’ law. The resulting Birks parameter kB ranges from (0.0066±0.0016) to (0.0076±0.0003) cm/MeV. In the first approach, the α -particle light response was measured simultaneously with the light response of recoil protons produced via neutron–proton elastic scattering. This enabled a first time a direct comparison of kB describing the proton and the α -particle response of LAB based scintillator. The observed kB values describing the two light response functions deviate by more than 5σ . The presented results are valuable for all current and future detectors, using LAB based scintillator as target, since they depend on an accurate knowledge of the scintillator response to different particles.« less

MatLab Script and Functional Programming

NASA Technical Reports Server (NTRS)

Shaykhian, Gholam Ali

2007-01-01

MatLab Script and Functional Programming: MatLab is one of the most widely used very high level programming languages for scientific and engineering computations. It is very user-friendly and needs practically no formal programming knowledge. Presented here are MatLab programming aspects and not just the MatLab commands for scientists and engineers who do not have formal programming training and also have no significant time to spare for learning programming to solve their real world problems. Specifically provided are programs for visualization. The MatLab seminar covers the functional and script programming aspect of MatLab language. Specific expectations are: a) Recognize MatLab commands, script and function. b) Create, and run a MatLab function. c) Read, recognize, and describe MatLab syntax. d) Recognize decisions, loops and matrix operators. e) Evaluate scope among multiple files, and multiple functions within a file. f) Declare, define and use scalar variables, vectors and matrices.

Development and numerical/experimental characterization of a lab-scale flat flame reactor allowing the analysis of pulverized solid fuel devolatilization and oxidation at high heating rates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lemaire, R., E-mail: romain.lemaire@mines-douai.fr; Menanteau, S.

2016-01-15

This paper deals with the thorough characterization of a new experimental test bench designed to study the devolatilization and oxidation of pulverized fuel particles in a wide range of operating conditions. This lab-scale facility is composed of a fuel feeding system, the functioning of which has been optimized by computational fluid dynamics. It allows delivering a constant and time-independent mass flow rate of fuel particles which are pneumatically transported to the central injector of a hybrid McKenna burner using a carrier gas stream that can be inert or oxidant depending on the targeted application. A premixed propane/air laminar flat flamemore » stabilized on the porous part of the burner is used to generate the hot gases insuring the heating of the central coal/carrier-gas jet with a thermal gradient similar to those found in industrial combustors (>10{sup 5} K/s). In the present work, results issued from numerical simulations performed a priori to characterize the velocity and temperature fields in the reaction chamber have been analyzed and confronted with experimental measurements carried out by coupling particle image velocimetry, thermocouple and two-color pyrometry measurements so as to validate the order of magnitude of the heating rate delivered by such a new test bench. Finally, the main features of the flat flame reactor we developed have been discussed with respect to those of another laboratory-scale system designed to study coal devolatilization at a high heating rate.« less

Development and numerical/experimental characterization of a lab-scale flat flame reactor allowing the analysis of pulverized solid fuel devolatilization and oxidation at high heating rates

NASA Astrophysics Data System (ADS)

Lemaire, R.; Menanteau, S.

2016-01-01

This paper deals with the thorough characterization of a new experimental test bench designed to study the devolatilization and oxidation of pulverized fuel particles in a wide range of operating conditions. This lab-scale facility is composed of a fuel feeding system, the functioning of which has been optimized by computational fluid dynamics. It allows delivering a constant and time-independent mass flow rate of fuel particles which are pneumatically transported to the central injector of a hybrid McKenna burner using a carrier gas stream that can be inert or oxidant depending on the targeted application. A premixed propane/air laminar flat flame stabilized on the porous part of the burner is used to generate the hot gases insuring the heating of the central coal/carrier-gas jet with a thermal gradient similar to those found in industrial combustors (>105 K/s). In the present work, results issued from numerical simulations performed a priori to characterize the velocity and temperature fields in the reaction chamber have been analyzed and confronted with experimental measurements carried out by coupling particle image velocimetry, thermocouple and two-color pyrometry measurements so as to validate the order of magnitude of the heating rate delivered by such a new test bench. Finally, the main features of the flat flame reactor we developed have been discussed with respect to those of another laboratory-scale system designed to study coal devolatilization at a high heating rate.

Research on the enhancement of biological nitrogen removal at low temperatures from ammonium-rich wastewater by the bio-electrocoagulation technology in lab-scale systems, pilot-scale systems and a full-scale industrial wastewater treatment plant.

PubMed

Li, Liang; Qian, Guangsheng; Ye, Linlin; Hu, Xiaomin; Yu, Xin; Lyu, Weijian

2018-09-01

In cold areas, nitrogen removal performance of wastewater treatment plants (WWTP) declines greatly in winter. This paper systematically describes the enhancement effect of a periodic reverse electrocoagulation technology on biological nitrogen removal at low temperatures. The study showed that in the lab-scale systems, the electrocoagulation technology improved the biomass amount, enzyme activity and the amount of nitrogen removal bacteria (Nitrosomonas, Nitrobacter, Paracoccus, Thauera and Enterobacter). This enhanced nitrification and denitrification of activated sludge at low temperatures. In the pilot-scale systems, the electrocoagulation technology increased the relative abundance of cold-adapted microorganisms (Luteimonas and Trueperaceae) at low temperatures. In a full-scale industrial WWTP, comparison of data from winter 2015 and winter 2016 showed that effluent chemical oxygen demand (COD), NH 4 + -N, and NO 3 - -N reduced by 10.37, 3.84, and 136.43 t, respectively, throughout the winter, after installation of electrocoagulation devices. These results suggest that the electrocoagulation technology is able to improve the performance of activated sludge under low-temperature conditions. This technology provides a new way for upgrading of the performance of WWTPs in cold areas. Copyright © 2018 Elsevier Ltd. All rights reserved.

Quality by design: scale-up of freeze-drying cycles in pharmaceutical industry.

PubMed

Pisano, Roberto; Fissore, Davide; Barresi, Antonello A; Rastelli, Massimo

2013-09-01

This paper shows the application of mathematical modeling to scale-up a cycle developed with lab-scale equipment on two different production units. The above method is based on a simplified model of the process parameterized with experimentally determined heat and mass transfer coefficients. In this study, the overall heat transfer coefficient between product and shelf was determined by using the gravimetric procedure, while the dried product resistance to vapor flow was determined through the pressure rise test technique. Once model parameters were determined, the freeze-drying cycle of a parenteral product was developed via dynamic design space for a lab-scale unit. Then, mathematical modeling was used to scale-up the above cycle in the production equipment. In this way, appropriate values were determined for processing conditions, which allow the replication, in the industrial unit, of the product dynamics observed in the small scale freeze-dryer. This study also showed how inter-vial variability, as well as model parameter uncertainty, can be taken into account during scale-up calculations.

Experiences with lab-centric instruction

NASA Astrophysics Data System (ADS)

Titterton, Nathaniel; Lewis, Colleen M.; Clancy, Michael J.

2010-06-01

Lab-centric instruction emphasizes supervised, hands-on activities by substituting lab for lecture time. It combines a multitude of pedagogical techniques into the format of an extended, structured closed lab. We discuss the range of benefits for students, including increased staff interaction, frequent and varied self-assessments, integrated collaborative activities, and a systematic sequence of activities that gradually increases in difficulty. Instructors also benefit from a deeper window into student progress and understanding. We follow with discussion of our experiences in courses at U.C. Berkeley, and using data from some of these investigate the effects of lab-centric instruction on student learning, procrastination, and course pacing. We observe that the lab-centric format helped students on exams but hurt them on extended programming assignments, counter to our hypothesis. Additionally, we see no difference in self-ratings of procrastination and limited differences in ratings of course pace. We do find evidence that the students who choose to attend lab-centric courses are different in several important ways from students who choose to attend the same course in a non-lab-centric format.

Scale Factor and Noise Performance Tests of the Bendix Corporation Rate Gyro Assembly (RGA).

DTIC Science & Technology

1980-08-01

tiltmeters , seismometers, and an ambient temperature monitor. 3.2 Test Support Equipment Bendix supplied all necessary test support equipment and...001A 2-Axis Tiltmeter Electrotechnical Lab EV22C Portable Seismic Mon- itor (PRM) Sensors USAF Sieler Laboratory PSM Electronics Rockland 816...acquisition system recorded the tiltmeter , seismometer, and temperature data on magnetic tape. The seismic, tilt, and temperature information was filtered

Improving the Quality of Lab Reports by Using Them as Lab Instructions

NASA Astrophysics Data System (ADS)

Haagen-Schuetzenhoefer, Claudia

2012-10-01

Lab exercises are quite popular in teaching science. Teachers have numerous goals in mind when teaching science laboratories. Nevertheless, empirical research draws a heterogeneous picture of the benefits of lab work. Research has shown that it does not necessarily contribute to the enhancement of practical abilities or content knowledge. Lab activities are frequently based on recipe-like, step-by-step instructions ("cookbook style"), which do not motivate students to engage cognitively. Consequently, students put the emphasis on "task completion" or "manipulating equipment."2

Nurse competence scale: development and psychometric testing.

PubMed

Meretoja, Riitta; Isoaho, Hannu; Leino-Kilpi, Helena

2004-07-01

Self-assessment assists nurses to maintain and improve their practice by identifying their strengths and areas that may need to be further developed. Professional competence profiles encourage them to take an active part in the learning process of continuing education. Although competence recognition offers a way to motivate practising nurses to produce quality care, few measuring tools are available for this purpose. This paper describes the development and testing of the Nurse Competence Scale, an instrument with which the level of nurse competence can be assessed in different hospital work environments. The categories of the Nurse Competence Scale were derived from Benner's From Novice to Expert competency framework. A seven-step approach, including literature review and six expert groups, was used to identify and validate the indicators of nurse competence. After a pilot test, psychometric testing of the Nurse Competence Scale (content, construct and concurrent validity, and internal consistency) was undertaken with 498 nurses. The 73-item scale consists of seven categories, with responses on a visual analogy scale format. The frequency of using competencies was additionally tested with a four-point scale. Self-assessed overall scores indicated a high level of competence across categories. The Nurse Competence Scale data were normally distributed. The higher the frequency of using competencies, the higher was the self-assessed level of competence. Age and length of work experience had a positive but not very strong correlation with level of competence. According to the item analysis, the categories of the Nurse Competence Scale showed good internal consistency. The results provide strong evidence of the reliability and validity of the Nurse Competence Scale.

Attack of the Killer Fungus: A Hypothesis-Driven Lab Module †

PubMed Central

Sato, Brian K.

2013-01-01

Discovery-driven experiments in undergraduate laboratory courses have been shown to increase student learning and critical thinking abilities. To this end, a lab module involving worm capture by a nematophagous fungus was developed. The goals of this module are to enhance scientific understanding of the regulation of worm capture by soil-dwelling fungi and for students to attain a set of established learning goals, including the ability to develop a testable hypothesis and search for primary literature for data analysis, among others. Students in a ten-week majors lab course completed the lab module and generated novel data as well as data that agrees with the published literature. In addition, learning gains were achieved as seen through a pre-module and post-module test, student self-assessment, class exam, and lab report. Overall, this lab module enables students to become active participants in the scientific method while contributing to the understanding of an ecologically relevant model organism. PMID:24358387

Hemoglobin Test: MedlinePlus Lab Test Information

MedlinePlus

... page: https://medlineplus.gov/labtests/hemoglobintest.html Hemoglobin Test To use the sharing features on this page, please enable JavaScript. What is a Hemoglobin Test? A hemoglobin test measures the levels of hemoglobin ...

Procalcitonin Test: MedlinePlus Lab Test Information

MedlinePlus

... page: https://medlineplus.gov/labtests/procalcitonintest.html Procalcitonin Test To use the sharing features on this page, please enable JavaScript. What is a Procalcitonin Test? A procalcitonin test measures the level of procalcitonin ...

Amylase Test: MedlinePlus Lab Test Information

MedlinePlus

... page: https://medlineplus.gov/labtests/amylasetest.html Amylase Test To use the sharing features on this page, please enable JavaScript. What is an Amylase Test? An amylase test measures the amount of amylase ...

Hematocrit Test: MedlinePlus Lab Test Information

MedlinePlus

... page: https://medlineplus.gov/labtests/hematocrittest.html Hematocrit Test To use the sharing features on this page, please enable JavaScript. What is a Hematocrit Test? A hematocrit test is a type of blood ...

Dr. Monaco Examines Lab-on a-Chip

NASA Technical Reports Server (NTRS)

2003-01-01

Dr. Lisa Monaco, Marshall Space Flight Center's (MSFC's) project scientist for the Lab-on-a-Chip Applications Development (LOCAD) program, examines a lab on a chip. The small dots are actually ports where fluids and chemicals can be mixed or samples can be collected for testing. Tiny channels, only clearly visible under a microscope, form pathways between the ports. Many chemical and biological processes, previously conducted on large pieces of laboratory equipment, can now be performed on these small glass or plastic plates. Monaco and other researchers at MSFC in Huntsville, Alabama, are customizing the chips to be used for many space applications, such as monitoring microbes inside spacecraft and detecting life on other planets. The portable, handheld Lab-on-a Chip Application Development Portable Test System (LOCAD-PTS) made its debut flight aboard Discovery during the STS-116 mission launched December 9, 2006. The system allowed crew members to monitor their environment for problematic contaminants such as yeast, mold, and even E.coli, and salmonella. Once LOCAD-PTS reached the International Space Station (ISS), the Marshall team continued to manage the experiment, monitoring the study from a console in the Payload Operations Center at MSFC. The results of these studies will help NASA researchers refine the technology for future Moon and Mars missions. (NASA/MSFC/D.Stoffer)

Lab Report Blues

ERIC Educational Resources Information Center

Diaz, Andrew

2004-01-01

For middle school students, writing a formal lab report can be challenging. For middle level teachers, reading students lab reports can be overwhelming. After grading report after report with incomplete procedures, incorrect graphs, and missing conclusions, the author's frustration level was at an all-time high. Ready to try anything, he thought,…

Reforming Cookbook Labs

ERIC Educational Resources Information Center

Peters, Erin

2005-01-01

Deconstructing cookbook labs to require the students to be more thoughtful could break down perceived teacher barriers to inquiry learning. Simple steps that remove or disrupt the direct transfer of step-by-step procedures in cookbook labs make students think more critically about their process. Through trials in the author's middle school…

Chemical Analysis of Drinking Water Concentrates in the Four Lab Study

EPA Science Inventory

The purpose of the Four Lab study was to evaluate potential health effects from exposure to disinfection by-products (DBPs). Unchlorinated water taken from a full-scale drinking water treatment plant was concentrated and chlorinated to form DBPs. Both the unchlorinated (control...

9 CFR 201.72 - Scales; testing of.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Scales; testing of. 201.72 Section 201.72 Animals and Animal Products GRAIN INSPECTION, PACKERS AND STOCKYARDS ADMINISTRATION (PACKERS AND... § 201.72 Scales; testing of. (a) Each stockyard owner, market agency, dealer, packer, or live poultry...

9 CFR 442.4 - Testing of scales.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Testing of scales. 442.4 Section 442.4 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE REGULATORY... LABELING AND PROCEDURES AND REQUIREMENTS FOR ACCURATE WEIGHTS § 442.4 Testing of scales. (a) The operator...

9 CFR 442.4 - Testing of scales.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Testing of scales. 442.4 Section 442.4 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE REGULATORY... LABELING AND PROCEDURES AND REQUIREMENTS FOR ACCURATE WEIGHTS § 442.4 Testing of scales. (a) The operator...

9 CFR 201.72 - Scales; testing of.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Scales; testing of. 201.72 Section 201.72 Animals and Animal Products GRAIN INSPECTION, PACKERS AND STOCKYARDS ADMINISTRATION (PACKERS AND... § 201.72 Scales; testing of. (a) Each stockyard owner, market agency, dealer, packer, or live poultry...

9 CFR 442.4 - Testing of scales.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Testing of scales. 442.4 Section 442.4 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE REGULATORY... LABELING AND PROCEDURES AND REQUIREMENTS FOR ACCURATE WEIGHTS § 442.4 Testing of scales. (a) The operator...

9 CFR 442.4 - Testing of scales.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Testing of scales. 442.4 Section 442.4 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE REGULATORY... LABELING AND PROCEDURES AND REQUIREMENTS FOR ACCURATE WEIGHTS § 442.4 Testing of scales. (a) The operator...

9 CFR 442.4 - Testing of scales.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Testing of scales. 442.4 Section 442.4 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE REGULATORY... LABELING AND PROCEDURES AND REQUIREMENTS FOR ACCURATE WEIGHTS § 442.4 Testing of scales. (a) The operator...

Introducing ADS Labs

NASA Astrophysics Data System (ADS)

Accomazzi, Alberto; Henneken, E.; Grant, C. S.; Kurtz, M. J.; Di Milia, G.; Luker, J.; Thompson, D. M.; Bohlen, E.; Murray, S. S.

2011-05-01

ADS Labs is a platform that ADS is introducing in order to test and receive feedback from the community on new technologies and prototype services. Currently, ADS Labs features a new interface for abstract searches, faceted filtering of results, visualization of co-authorship networks, article-level recommendations, and a full-text search service. The streamlined abstract search interface provides a simple, one-box search with options for ranking results based on a paper relevancy, freshness, number of citations, and downloads. In addition, it provides advanced rankings based on collaborative filtering techniques. The faceted filtering interface allows users to narrow search results based on a particular property or set of properties ("facets"), allowing users to manage large lists and explore the relationship between them. For any set or sub-set of records, the co-authorship network can be visualized in an interactive way, offering a view of the distribution of contributors and their inter-relationships. This provides an immediate way to detect groups and collaborations involved in a particular research field. For a majority of papers in Astronomy, our new interface will provide a list of related articles of potential interest. The recommendations are based on a number of factors, including text similarity, citations, and co-readership information. The new full-text search interface allows users to find all instances of particular words or phrases in the body of the articles in our full-text archive. This includes all of the scanned literature in ADS as well as a select portion of the current astronomical literature, including ApJ, ApJS, AJ, MNRAS, PASP, A&A, and soon additional content from Springer journals. Fulltext search results include a list of the matching papers as well as a list of "snippets" of text highlighting the context in which the search terms were found. ADS Labs is available at http://adslabs.org

Validation study of the in vitro skin irritation test with the LabCyte EPI-MODEL24.

PubMed

Kojima, Hajime; Ando, Yoko; Idehara, Kenji; Katoh, Masakazu; Kosaka, Tadashi; Miyaoka, Etsuyoshi; Shinoda, Shinsuke; Suzuki, Tamie; Yamaguchi, Yoshihiro; Yoshimura, Isao; Yuasa, Atsuko; Watanabe, Yukihiko; Omori, Takashi

2012-03-01

A validation study on an in vitro skin irritation assay was performed with the reconstructed human epidermis (RhE) LabCyte EPI-MODEL24, developed by Japan Tissue Engineering Co. Ltd (Gamagori, Japan). The protocol that was followed in the current study was an optimised version of the EpiSkin protocol (LabCyte assay). According to the United Nations Globally Harmonised System (UN GHS) of classification for assessing the skin irritation potential of a chemical, 12 irritants and 13 non-irritants were validated by a minimum of six laboratories from the Japanese Society for Alternatives to Animal Experiments (JSAAE) skin irritation assay validation study management team (VMT). The 25 chemicals were listed in the European Centre for the Validation of Alternative Methods (ECVAM) performance standards. The reconstructed tissues were exposed to the chemicals for 15 minutes and incubated for 42 hours in fresh culture medium. Subsequently, the level of interleukin-1 alpha (IL-1 α) present in the conditioned medium was measured, and tissue viability was assessed by using the MTT assay. The results of the MTT assay obtained with the LabCyte EPI-MODEL24 (LabCyte MTT assay) demonstrated high within-laboratory and between-laboratory reproducibility, as well as high accuracy for use as a stand-alone assay to distinguish skin irritants from non-irritants. In addition, the IL-1α release measurements in the LabCyte assay were clearly unnecessary for the success of this model in the classification of chemicals for skin irritation potential. 2012 FRAME.

Designing a ruggedisation lab to characterise materials for harsh environments.

PubMed

Frazzette, Nicholas; Jethva, Janak; Mehta, Khanjan; Stapleton, Joshua J; Randall, Clive

Designing products for use in developing countries presents a unique set of challenges including harsh operating environments, costly repairs and maintenance, and users with varying degrees of education and device familiarity. For products to be robust, adaptable and durable, they need to be ruggedised for environmental factors such as high temperature and humidity as well as different operational conditions such as shock and chemical exposure. The product characterisation and ruggedisation processes require specific expertise and resources that are seldom available outside of large corporations and elite national research labs. There is no standardised process since product needs strongly depend on the context and user base, making it particularly onerous for underfunded start-ups and academic groups. Standardised protocols that identify essential lab testing regimens for specific contexts and user groups can complement field-testing and accelerate the product development process while reducing costs. This article synthesises current methods and strategies for product testing employed by large corporations as well as defence-related entities. A technological and organisational framework for a service-for-fee product characterisation and ruggedisation lab that reduces costs and shortens the timespan from product invention to commercial launch in harsh settings is presented.

Using Lab Notebooks to Examine Students' Engagement in Modeling in an Upper-Division Electronics Lab Course

ERIC Educational Resources Information Center

Stanley, Jacob T.; Su, Weifeng; Lewandowski, H. J.

2017-01-01

We demonstrate how students' use of modeling can be examined and assessed using student notebooks collected from an upper-division electronics lab course. The use of models is a ubiquitous practice in undergraduate physics education, but the process of constructing, testing, and refining these models is much less common. We focus our attention on…

CESIUM REMOVAL FROM TANKS 241-AN-103 & 241-SX-105 & 241-AZ-101 & 241AZ-102 COMPOSITE FOR TESTING IN BENCH SCALE STEAM REFORMER

DOE Office of Scientific and Technical Information (OSTI.GOV)

DUNCAN JB; HUBER HJ

2011-04-21

This report documents the preparation of three actual Hanford tank waste samples for shipment to the Savannah River National Laboratory (SRNL). Two of the samples were dissolved saltcakes from tank 241-AN-103 (hereafter AN-103) and tank 241-SX-105 (hereafter SX-105); one sample was a supernate composite from tanks 241-AZ-101 and 241-AZ-102 (hereafter AZ-101/102). The preparation of the samples was executed following the test plans LAB-PLAN-10-00006, Test Plan for the Preparation of Samples from Hanford Tanks 241-SX-105, 241-AN-103, 241-AN-107, and LAB-PLN-l0-00014, Test Plan for the Preparation of a Composite Sample from Hanford Tanks 241-AZ-101 and 241-AZ-102 for Steam Reformer Testing at the Savannahmore » River National Laboratory. All procedural steps were recorded in laboratory notebook HNF-N-274 3. Sample breakdown diagrams for AN-103 and SX-105 are presented in Appendix A. The tank samples were prepared in support of a series of treatability studies of the Fluidized Bed Steam Reforming (FBSR) process using a Bench-Scale Reformer (BSR) at SRNL. Tests with simulants have shown that the FBSR mineralized waste form is comparable to low-activity waste glass with respect to environmental durability (WSRC-STI-2008-00268, Mineralization of Radioactive Wastes by Fluidized Bed Steam Reforming (FBSR): Comparisons to Vitreous Waste Forms and Pertinent Durability Testing). However, a rigorous assessment requires long-term performance data from FBSR product formed from actual Hanford tank waste. Washington River Protection Solutions, LLC (WRPS) has initiated a Waste Form Qualification Program (WP-5.2.1-2010-001, Fluidized Bed Steam Reformer Low-level Waste Form Qualification) to gather the data required to demonstrate that an adequate FBSR mineralized waste form can be produced. The documentation of the selection process of the three tank samples has been separately reported in RPP-48824, Sample Selection Process for Bench-Scale Steam Reforming Treatability Studies

Arduino: a low-cost multipurpose lab equipment.

PubMed

D'Ausilio, Alessandro

2012-06-01

Typical experiments in psychological and neurophysiological settings often require the accurate control of multiple input and output signals. These signals are often generated or recorded via computer software and/or external dedicated hardware. Dedicated hardware is usually very expensive and requires additional software to control its behavior. In the present article, I present some accuracy tests on a low-cost and open-source I/O board (Arduino family) that may be useful in many lab environments. One of the strengths of Arduinos is the possibility they afford to load the experimental script on the board's memory and let it run without interfacing with computers or external software, thus granting complete independence, portability, and accuracy. Furthermore, a large community has arisen around the Arduino idea and offers many hardware add-ons and hundreds of free scripts for different projects. Accuracy tests show that Arduino boards may be an inexpensive tool for many psychological and neurophysiological labs.

Virtual Lab to Develop Achievement in Electronic Circuits for Hearing-Impaired Students

ERIC Educational Resources Information Center

Baladoh, S. M.; Elgamal, A. F.; Abas, H. A.

2017-01-01

This paper aims to report and discuss the use of a virtual lab for developing achievement in electronic circuits for hearing-impaired students. Results from a number of studies have proved that the virtual lab allowed students to build and test a wide variety of electronic circuits. The present study was implemented to investigate the…

Small-scale Starshade Test

NASA Image and Video Library

2016-08-09

A test of a small-scale starshade model (58 cm), made from metal, in a dry lake bed in central Nevada's Smith Creek, took place from May to June 2014. Nineteen different versions of the miniaturized starshade were tested over five days. The tests revealed that a starshade, or external occulter, is capable of blocking starlight to a degree that reveals the relatively dim reflected light of a planet next to its brighter star. Like holding your hand up to block sunlight, the starshade works to block excessive starlight from the "eyes" of a space telescope like Hubble. http://photojournal.jpl.nasa.gov/catalog/PIA20902

Test Plan: WIPP bin-scale CH TRU waste tests

DOE Office of Scientific and Technical Information (OSTI.GOV)

Molecke, M.A.

1990-08-01

This WIPP Bin-Scale CH TRU Waste Test program described herein will provide relevant composition and kinetic rate data on gas generation and consumption resulting from TRU waste degradation, as impacted by synergistic interactions due to multiple degradation modes, waste form preparation, long-term repository environmental effects, engineered barrier materials, and, possibly, engineered modifications to be developed. Similar data on waste-brine leachate compositions and potentially hazardous volatile organic compounds released by the wastes will also be provided. The quantitative data output from these tests and associated technical expertise are required by the WIPP Performance Assessment (PA) program studies, and for the scientificmore » benefit of the overall WIPP project. This Test Plan describes the necessary scientific and technical aspects, justifications, and rational for successfully initiating and conducting the WIPP Bin-Scale CH TRU Waste Test program. This Test Plan is the controlling scientific design definition and overall requirements document for this WIPP in situ test, as defined by Sandia National Laboratories (SNL), scientific advisor to the US Department of Energy, WIPP Project Office (DOE/WPO). 55 refs., 16 figs., 19 tabs.« less

Revisiting lab-on-a-chip technology for drug discovery.

PubMed

Neuži, Pavel; Giselbrecht, Stefan; Länge, Kerstin; Huang, Tony Jun; Manz, Andreas

2012-08-01

The field of microfluidics or lab-on-a-chip technology aims to improve and extend the possibilities of bioassays, cell biology and biomedical research based on the idea of miniaturization. Microfluidic systems allow more accurate modelling of physiological situations for both fundamental research and drug development, and enable systematic high-volume testing for various aspects of drug discovery. Microfluidic systems are in development that not only model biological environments but also physically mimic biological tissues and organs; such 'organs on a chip' could have an important role in expediting early stages of drug discovery and help reduce reliance on animal testing. This Review highlights the latest lab-on-a-chip technologies for drug discovery and discusses the potential for future developments in this field.

Status of chemistry lab safety in Nepal.

PubMed

Kandel, Krishna Prasad; Neupane, Bhanu Bhakta; Giri, Basant

2017-01-01

Chemistry labs can become a dangerous environment for students as the lab exercises involve hazardous chemicals, glassware, and equipment. Approximately one hundred thousand students take chemistry laboratory classes annually in Nepal. We conducted a survey on chemical lab safety issues across Nepal. In this paper, we assess the safety policy and equipment, protocols and procedures followed, and waste disposal in chemistry teaching labs. Significant population of the respondents believed that there is no monitoring of the lab safety in their lab (p<0.001). Even though many labs do not allow food and beverages inside lab and have first aid kits, they lack some basic safety equipment. There is no institutional mechanism to dispose lab waste and chemical waste is disposed haphazardly. Majority of the respondents believed that the safety training should be a part of educational training (p = 0.001) and they would benefit from short course and/or workshop on lab safety (p<0.001).

Status of chemistry lab safety in Nepal

PubMed Central

Kandel, Krishna Prasad; Neupane, Bhanu Bhakta

2017-01-01

Chemistry labs can become a dangerous environment for students as the lab exercises involve hazardous chemicals, glassware, and equipment. Approximately one hundred thousand students take chemistry laboratory classes annually in Nepal. We conducted a survey on chemical lab safety issues across Nepal. In this paper, we assess the safety policy and equipment, protocols and procedures followed, and waste disposal in chemistry teaching labs. Significant population of the respondents believed that there is no monitoring of the lab safety in their lab (p<0.001). Even though many labs do not allow food and beverages inside lab and have first aid kits, they lack some basic safety equipment. There is no institutional mechanism to dispose lab waste and chemical waste is disposed haphazardly. Majority of the respondents believed that the safety training should be a part of educational training (p = 0.001) and they would benefit from short course and/or workshop on lab safety (p<0.001). PMID:28644869

SCALE-UP OF RAPID SMALL-SCALE ADSORPTION TESTS TO FIELD-SCALE ADSORBERS: THEORETICAL AND EXPERIMENTAL BASIS

EPA Science Inventory

Design of full-scale adsorption systems typically includes expensive and time-consuming pilot studies to simulate full-scale adsorber performance. Accordingly, the rapid small-scale column test (RSSCT) was developed and evaluated experimentally. The RSSCT can simulate months of f...

Age Effects on Wechsler Adult Intelligence Scale-Revised Tests.

ERIC Educational Resources Information Center

Sattler, Jerome M.

1982-01-01

Studied age norms for 11 individual Wechsler Adult Intelligence Scale-Revised (WAIS-R) tests. Digit Symbol showed the most decline. Results suggest that fluid intelligence, as measured by the performance scale tests, shows more of a decline with age than crystallized intelligence, as measured by the verbal scale tests. (Author)

27 CFR 19.776 - Record of scale tests.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Record of scale tests. 19.776 Section 19.776 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU... of scale tests. Proprietors shall maintain records of results of tests conducted in accordance with...

SenseLab

PubMed Central

Crasto, Chiquito J.; Marenco, Luis N.; Liu, Nian; Morse, Thomas M.; Cheung, Kei-Hoi; Lai, Peter C.; Bahl, Gautam; Masiar, Peter; Lam, Hugo Y.K.; Lim, Ernest; Chen, Huajin; Nadkarni, Prakash; Migliore, Michele; Miller, Perry L.; Shepherd, Gordon M.

2009-01-01

This article presents the latest developments in neuroscience information dissemination through the SenseLab suite of databases: NeuronDB, CellPropDB, ORDB, OdorDB, OdorMapDB, ModelDB and BrainPharm. These databases include information related to: (i) neuronal membrane properties and neuronal models, and (ii) genetics, genomics, proteomics and imaging studies of the olfactory system. We describe here: the new features for each database, the evolution of SenseLab’s unifying database architecture and instances of SenseLab database interoperation with other neuroscience online resources. PMID:17510162

Customer Avionics Interface Development and Analysis (CAIDA) Lab DEWESoft Display Creation

NASA Technical Reports Server (NTRS)

Coffey, Connor

2015-01-01

The Customer Avionics Interface Development and Analysis (CAIDA) Lab supports the testing of the Launch Control System (LCS), NASA's command and control system for the Space Launch System (SLS), Orion Multi-Purpose Crew Vehicle (MPCV), and ground support equipment. The objectives of the year-long internship were to support day-to-day operations of the CAIDA Lab, create prelaunch and tracking displays for Orion's Exploration Flight Test 1 (EFT-1), and create a program to automate the creation of displays for SLS and MPCV to be used by CAIDA and the Record and Playback Subsystem (RPS).

Lab-on a-Chip

NASA Technical Reports Server (NTRS)

1999-01-01

Labs on chips are manufactured in many shapes and sizes and can be used for numerous applications, from medical tests to water quality monitoring to detecting the signatures of life on other planets. The eight holes on this chip are actually ports that can be filled with fluids or chemicals. Tiny valves control the chemical processes by mixing fluids that move in the tiny channels that look like lines, connecting the ports. Scientists at NASA's Marshall Space Flight Center (MSFC) in Huntsville, Alabama designed this chip to grow biological crystals on the International Space Station (ISS). Through this research, they discovered that this technology is ideally suited for solving the challenges of the Vision for Space Exploration. For example, thousands of chips the size of dimes could be loaded on a Martian rover looking for biosignatures of past or present life. Other types of chips could be placed in handheld devices used to monitor microbes in water or to quickly conduct medical tests on astronauts. The portable, handheld Lab-on-a Chip Application Development Portable Test System (LOCAD-PTS) made its debut flight aboard Discovery during the STS-116 mission launched December 9, 2006. The system allowed crew members to monitor their environment for problematic contaminants such as yeast, mold, and even E.coli, and salmonella. Once LOCAD-PTS reached the ISS, the Marshall team continued to manage the experiment, monitoring the study from a console in the Payload Operations Center at MSFC. The results of these studies will help NASA researchers refine the technology for future Moon and Mars missions. (NASA/MSFC/D.Stoffer)

The Expanded Large Scale Gap Test

DTIC Science & Technology

1987-03-01

NSWC TR 86-32 DTIC THE EXPANDED LARGE SCALE GAP TEST BY T. P. LIDDIARD D. PRICE RESEARCH AND TECHNOLOGY DEPARTMENT ’ ~MARCH 1987 Ap~proved for public...arises, to reduce the spread in the LSGT 50% gap value.) The worst charges, such as those with the highest or lowest densities, the largest re-pressed...Arlington, VA 22217 PE 62314N INS3A 1 RJ14E31 7R4TBK 11 TITLE (Include Security CIlmsilficatiorn The Expanded Large Scale Gap Test . 12. PEIRSONAL AUTHOR() T

Innovations in dynamic test restraint systems

NASA Technical Reports Server (NTRS)

Fuld, Christopher J.

1990-01-01

Recent launch system development programs have led to a new generation of large scale dynamic tests. The variety of test scenarios share one common requirement: restrain and capture massive high velocity flight hardware with no structural damage. The Space Systems Lab of McDonnell Douglas developed a remarkably simple and cost effective approach to such testing using ripstitch energy absorbers adapted from the sport of technical rockclimbing. The proven system reliability of the capture system concept has led to a wide variety of applications in test system design and in aerospace hardware design.

Affordable Imaging Lab for Noninvasive Analysis of Biomass and Early Vigour in Cereal Crops

PubMed Central

2018-01-01

Plant phenotyping by imaging allows automated analysis of plants for various morphological and physiological traits. In this work, we developed a low-cost RGB imaging phenotyping lab (LCP lab) for low-throughput imaging and analysis using affordable imaging equipment and freely available software. LCP lab comprising RGB imaging and analysis pipeline is set up and demonstrated with early vigour analysis in wheat. Using this lab, a few hundred pots can be photographed in a day and the pots are tracked with QR codes. The software pipeline for both imaging and analysis is built from freely available software. The LCP lab was evaluated for early vigour analysis of five wheat cultivars. A high coefficient of determination (R2 0.94) was obtained between the dry weight and the projected leaf area of 20-day-old wheat plants and R2 of 0.9 for the relative growth rate between 10 and 20 days of plant growth. Detailed description for setting up such a lab is provided together with custom scripts built for imaging and analysis. The LCP lab is an affordable alternative for analysis of cereal crops when access to a high-throughput phenotyping facility is unavailable or when the experiments require growing plants in highly controlled climate chambers. The protocols described in this work are useful for building affordable imaging system for small-scale research projects and for education. PMID:29850536

Integrating Robotic Observatories into Astronomy Labs

NASA Astrophysics Data System (ADS)

Ruch, Gerald T.

2015-01-01

The University of St. Thomas (UST) and a consortium of five local schools is using the UST Robotic Observatory, housing a 17' telescope, to develop labs and image processing tools that allow easy integration of observational labs into existing introductory astronomy curriculum. Our lab design removes the burden of equipment ownership by sharing access to a common resource and removes the burden of data processing by automating processing tasks that are not relevant to the learning objectives.Each laboratory exercise takes place over two lab periods. During period one, students design and submit observation requests via the lab website. Between periods, the telescope automatically acquires the data and our image processing pipeline produces data ready for student analysis. During period two, the students retrieve their data from the website and perform the analysis. The first lab, 'Weighing Jupiter,' was successfully implemented at UST and several of our partner schools. We are currently developing a second lab to measure the age of and distance to a globular cluster.

Commerce lab: Mission analysis and payload integration study

NASA Technical Reports Server (NTRS)

1984-01-01

Conceived as one or more arrays of carriers which would fly aboard space shuttle, Commerce Lab can provide a point of focus for implementing a series of shuttle flights, co-sponsored by NASA and U.S. domestic concerns, for performing materials processing in research and pre-commercial investigations. As an orbiting facility for testing, developing, and implementing hardware and procedures, Commerce Lab can enhance space station development and hasten space platform production capability. Tasks considered include: (1) synthesis of user requirements and identification of common element and voids; (2) definition of performance and infrastructure requirement and alternative approaches; and (3) carrier, mission model, and infrastructure development.

Hydroshear Simulation Lab Test 2

DOE Data Explorer

Bauer, Steve

2014-08-01

This data file is for test 2. In this test a sample of granite with a pre cut (man made fracture) is confined, heated and differential stress is applied. max temperature in this this system development test is 95C. test details on the spreadsheets--note thta there are 2 spreadsheets

DNA Microarray Wet Lab Simulation Brings Genomics into the High School Curriculum

ERIC Educational Resources Information Center

Campbell, A. Malcolm; Zanta, Carolyn A.; Heyer, Laurie J.; Kittinger, Ben; Gabric, Kathleen M.; Adler, Leslie

2006-01-01

We have developed a wet lab DNA microarray simulation as part of a complete DNA microarray module for high school students. The wet lab simulation has been field tested with high school students in Illinois and Maryland as well as in workshops with high school teachers from across the nation. Instead of using DNA, our simulation is based on pH…

A preliminary and qualitative study of resource ratio theory to nitrifying lab-scale bioreactors

PubMed Central

Bellucci, Micol; Ofiţeru, Irina D; Beneduce, Luciano; Graham, David W; Head, Ian M; Curtis, Thomas P

2015-01-01

The incorporation of microbial diversity in design would ideally require predictive theory that would relate operational parameters to the numbers and distribution of taxa. Resource ratio-theory (RRT) might be one such theory. Based on Monod kinetics, it explains diversity in function of resource-ratio and richness. However, to be usable in biological engineered system, the growth parameters of all the bacteria under consideration and the resource supply and diffusion parameters for all the relevant nutrients should be determined. This is challenging, but plausible, at least for low diversity groups with simple resource requirements like the ammonia oxidizing bacteria (AOB). One of the major successes of RRT was its ability to explain the ‘paradox of enrichment’ which states that diversity first increases and then decreases with resource richness. Here, we demonstrate that this pattern can be seen in lab-scale-activated sludge reactors and parallel simulations that incorporate the principles of RRT in a floc-based system. High and low ammonia and oxygen were supplied to continuous flow bioreactors with resource conditions correlating with the composition and diversity of resident AOB communities based on AOB 16S rDNA clone libraries. Neither the experimental work nor the simulations are definitive proof for the application of RRT in this context. However, it is sufficient evidence that such approach might work and justify a more rigorous investigation. PMID:25874592

Cortisol Test: MedlinePlus Lab Test Information

MedlinePlus

... page: https://medlineplus.gov/labtests/cortisoltest.html Cortisol Test To use the sharing features on this page, please enable JavaScript. What is a Cortisol Test? Cortisol is a hormone that affects almost every ...

Lipase Test: MedlinePlus Lab Test Information

MedlinePlus

... page: https://medlineplus.gov/labtests/lipasetest.html Lipase Test To use the sharing features on this page, please enable JavaScript. What is a lipase test? Lipase is a type of protein made by ...

AST Test: MedlinePlus Lab Test Information

MedlinePlus

... page: https://medlineplus.gov/labtests/asttest.html AST Test To use the sharing features on this page, please enable JavaScript. What is an AST Test? AST (aspartate aminotransferase) is an enzyme that is ...

Chlamydia Test: MedlinePlus Lab Test Information

MedlinePlus

... page: https://medlineplus.gov/labtests/chlamydiatest.html Chlamydia Test To use the sharing features on this page, please enable JavaScript. What is a Chlamydia Test? Chlamydia is one of the most common sexually ...

Improving the Quality of Lab Reports by Using Them as Lab Instructions

ERIC Educational Resources Information Center

Haagen-Schuetzenhoefer, Claudia

2012-01-01

Lab exercises are quite popular in teaching science. Teachers have numerous goals in mind when teaching science laboratories. Nevertheless, empirical research draws a heterogeneous picture of the benefits of lab work. Research has shown that it does not necessarily contribute to the enhancement of practical abilities or content knowledge. Lab…

Computational Labs Using VPython Complement Conventional Labs in Online and Regular Physics Classes

NASA Astrophysics Data System (ADS)

Bachlechner, Martina E.

2009-03-01

Fairmont State University has developed online physics classes for the high-school teaching certificate based on the text book Matter and Interaction by Chabay and Sherwood. This lead to using computational VPython labs also in the traditional class room setting to complement conventional labs. The computational modeling process has proven to provide an excellent basis for the subsequent conventional lab and allows for a concrete experience of the difference between behavior according to a model and realistic behavior. Observations in the regular class room setting feed back into the development of the online classes.

Lab-scale co-digestion of kitchen waste and brown water for a preliminary performance evaluation of a decentralized waste and wastewater management.

PubMed

Lavagnolo, Maria Cristina; Girotto, Francesca; Hirata, Osamu; Cossu, Raffaello

2017-08-01

An overall interaction is manifested between wastewater and solid waste management schemes. At the Laboratory of Environmental Engineering (LISA) of the University of Padova, Italy, the scientific and technical implications of putting into practice a decentralized waste and wastewater treatment based on the separation of grey water, brown water (BW - faecal matter) and yellow water (YW - urine) are currently undergoing investigation in the Aquanova Project. An additional aim of this concept is the source segregation of kitchen waste (KW) for subsequent anaerobic co-digestion with BW. To determine an optimal mixing ratio and temperature for use in the treatment of KW, BW, and eventually YW, by means of anaerobic digestion, a series of lab-scale batch tests were performed. Organic mixtures of KW and BW performed much better (max. 520mlCH 4 /gVS) in terms of methane yields than the individual substrates alone (max. 220mlCH 4 /gVS). A small concentration of urine proved to have a positive effect on anaerobic digestion performance, possibly due to the presence of micronutrients in YW. When considering high YW concentrations in the anaerobically digested mixtures, no ammonia inhibition was observed until a 30% and 10% YW content was added under mesophilic and thermophilic conditions, respectively. Copyright © 2017 Elsevier Ltd. All rights reserved.

TXESS Revolution: Utilizing TERC's EarthLabs Cryosphere Module to Support Professional Development of Texas Teachers

NASA Astrophysics Data System (ADS)

Odell, M.; Ellins, K. K.; Polito, E. J.; Castillo Comer, C. A.; Stocks, E.; Manganella, K.; Ledley, T. S.

2010-12-01

TERC’s EarthLabs project provides rigorous and engaging Earth and environmental science labs. Four existing modules illustrate sequences for learning science concepts through data analysis activities and hands-on experiments. A fifth module, developed with NSF, comprises a series of linked inquiry based activities focused on the cryosphere to help students understand concepts around change over time on multiple and embedded time scales. Teachers recruited from the NSF-OEDG-sponsored Texas Earth and Space Science (TXESS) Revolution teacher professional development program conducted a pedagogical review of the Cryosphere EarthLabs module and provided feedback on how well the materials matched high school needs in Texas and were aligned with state and national standards. Five TXESS Revolution teachers field tested the materials in their classrooms and then trained other TXESS Revolution teachers on their implementation during spring and summer 2010. Here we report on the results of PD delivery during the summer 2010 TXESS Revolution summer institute as determined by (1) a set of evaluation instruments that included a pre-post concept map activity to assess changes in workshop teachers’ understanding of the concepts presented, a pre-post test content knowledge test, and a pre-post survey of teachers’ comfort in teaching the Texas Earth and Space Science standards addressed by the module; (2) teacher reflections; and (3) focus group responses. The findings reveal that the teachers liked the module activities and felt they could use them to teach Environmental and Earth Science. They appreciated that the sequence of activities contributed to a deeper understanding and observed that the variety of methods used to present the information accommodates different learning styles. Information about the cryosphere was new to all the teachers. The content knowledge tests reveal that although teachers made appreciable gains, their understanding of cryosphere, how it changes

The Math You Need at Baylor University: Improving Quantitative Skills in an Introductory Geology Lab Course

NASA Astrophysics Data System (ADS)

Browning, S.

2014-12-01

The Math You Need (TMYN) modules were introduced at Baylor University in fall 2012 to address issues of math anxiety common among freshmen non-majors completing their lab science requirement, and to reduce lab time spent reviewing basic math concepts. Modules and associated assessment questions commonly use geoscience examples to illustrate the mathematical principles involved, reinforcing topics addressed in lab. Large enrollments in the course selected for these modules necessitate multiple graduate teaching assistants in the lab, making the online nature of the modules and minimal required involvement of the teaching assistants even more valuable. Students completed three selected modules before encountering associated topics in lab, as well as a pre and post-test to gauge improvement. This presentation will review lessons learned and changes made in the first two years of TMYN at Baylor. Results indicate continued increases in mean pre to post test scores (e.g. 3.2% in fall 2012 to 11.9% in spring 2014), percentage of student pre to post- test improvement (59% in fall 2012 to 72% in spring 2014) and student participation (95 in fall 2012 to 186 in spring 2014). Continued use of these modules is anticipated.

Space Launch System Scale Model Acoustic Test Ignition Overpressure Testing

NASA Technical Reports Server (NTRS)

Nance, Donald K.; Liever, Peter A.

2015-01-01

The overpressure phenomenon is a transient fluid dynamic event occurring during rocket propulsion system ignition. This phenomenon results from fluid compression of the accelerating plume gas, subsequent rarefaction, and subsequent propagation from the exhaust trench and duct holes. The high-amplitude unsteady fluid-dynamic perturbations can adversely affect the vehicle and surrounding structure. Commonly known as ignition overpressure (IOP), this is an important design-to environment for the Space Launch System (SLS) that NASA is currently developing. Subscale testing is useful in validating and verifying the IOP environment. This was one of the objectives of the Scale Model Acoustic Test (SMAT), conducted at Marshall Space Flight Center (MSFC). The test data quantifies the effectiveness of the SLS IOP suppression system and improves the analytical models used to predict the SLS IOP environments. The reduction and analysis of the data gathered during the SMAT IOP test series requires identification and characterization of multiple dynamic events and scaling of the event waveforms to provide the most accurate comparisons to determine the effectiveness of the IOP suppression systems. The identification and characterization of the overpressure events, the waveform scaling, the computation of the IOP suppression system knockdown factors, and preliminary comparisons to the analytical models are discussed.

Space Launch System Scale Model Acoustic Test Ignition Overpressure Testing

NASA Technical Reports Server (NTRS)

Nance, Donald; Liever, Peter; Nielsen, Tanner

2015-01-01

The overpressure phenomenon is a transient fluid dynamic event occurring during rocket propulsion system ignition. This phenomenon results from fluid compression of the accelerating plume gas, subsequent rarefaction, and subsequent propagation from the exhaust trench and duct holes. The high-amplitude unsteady fluid-dynamic perturbations can adversely affect the vehicle and surrounding structure. Commonly known as ignition overpressure (IOP), this is an important design-to environment for the Space Launch System (SLS) that NASA is currently developing. Subscale testing is useful in validating and verifying the IOP environment. This was one of the objectives of the Scale Model Acoustic Test, conducted at Marshall Space Flight Center. The test data quantifies the effectiveness of the SLS IOP suppression system and improves the analytical models used to predict the SLS IOP environments. The reduction and analysis of the data gathered during the SMAT IOP test series requires identification and characterization of multiple dynamic events and scaling of the event waveforms to provide the most accurate comparisons to determine the effectiveness of the IOP suppression systems. The identification and characterization of the overpressure events, the waveform scaling, the computation of the IOP suppression system knockdown factors, and preliminary comparisons to the analytical models are discussed.

Spaceport Processing System Development Lab

NASA Technical Reports Server (NTRS)

Dorsey, Michael

2013-01-01

The Spaceport Processing System Development Lab (SPSDL), developed and maintained by the Systems Hardware and Engineering Branch (NE-C4), is a development lab with its own private/restricted networks. A private/restricted network is a network with restricted or no communication with other networks. This allows users from different groups to work on their own projects in their own configured environment without interfering with others utilizing their resources in the lab. The different networks being used in the lab have no way to talk with each other due to the way they are configured, so how a user configures his software, operating system, or the equipment doesn't interfere or carry over on any of the other networks in the lab. The SPSDL is available for any project in KSC that is in need of a lab environment. My job in the SPSDL was to assist in maintaining the lab to make sure it's accessible for users. This includes, but is not limited to, making sure the computers in the lab are properly running and patched with updated hardware/software. In addition to this, I also was to assist users who had issues in utilizing the resources in the lab, which may include helping to configure a restricted network for their own environment. All of this was to ensure workers were able to use the SPSDL to work on their projects without difficulty which would in turn, benefit the work done throughout KSC. When I wasn't working in the SPSDL, I would instead help other coworkers with smaller tasks which included, but wasn't limited to, the proper disposal, moving of, or search for essential equipment. I also, during the free time I had, used NASA's resources to increase my knowledge and skills in a variety of subjects related to my major as a computer engineer, particularly in UNIX, Networking, and Embedded Systems.

Off to the (Earthworm) Races: A Quick and Flexible Lab Experiment for Introductory Zoology Courses.

ERIC Educational Resources Information Center

Switzer, Paul V.; Fritz, Ann H.

2001-01-01

Presents a hands-on, investigative lab activity for use in an introductory zoology course. Tests the behavioral hypothesis that substrate texture affects earthworm locomotor ability. Provides background information on earthworm locomotion followed by details of the lab exercise. (NB)

SacLab: A toolbox for saccade analysis to increase usability of eye tracking systems in clinical ophthalmology practice.

PubMed

Cercenelli, Laura; Tiberi, Guido; Corazza, Ivan; Giannaccare, Giuseppe; Fresina, Michela; Marcelli, Emanuela

2017-01-01

Many open source software packages have been recently developed to expand the usability of eye tracking systems to study oculomotor behavior, but none of these is specifically designed to encompass all the main functions required for creating eye tracking tests and for providing the automatic analysis of saccadic eye movements. The aim of this study is to introduce SacLab, an intuitive, freely-available MATLAB toolbox based on Graphical User Interfaces (GUIs) that we have developed to increase the usability of the ViewPoint EyeTracker (Arrington Research, Scottsdale, AZ, USA) in clinical ophthalmology practice. SacLab consists of four processing modules that enable the user to easily create visual stimuli tests (Test Designer), record saccadic eye movements (Data Recorder), analyze the recorded data to automatically extract saccadic parameters of clinical interest (Data Analyzer) and provide an aggregate analysis from multiple eye movements recordings (Saccade Analyzer), without requiring any programming effort by the user. A demo application of SacLab to carry out eye tracking tests for the analysis of horizontal saccades was reported. We tested the usability of SacLab toolbox with three ophthalmologists who had no programming experience; the ophthalmologists were briefly trained in the use of SacLab GUIs and were asked to perform the demo application. The toolbox gained an enthusiastic feedback from all the clinicians in terms of intuitiveness, ease of use and flexibility. Test creation and data processing were accomplished in 52±21s and 46±19s, respectively, using the SacLab GUIs. SacLab may represent a useful tool to ease the application of the ViewPoint EyeTracker system in clinical routine in ophthalmology. Copyright © 2016 Elsevier Ltd. All rights reserved.

An LED Solar Simulator for Student Labs

ERIC Educational Resources Information Center

González, Manuel I.

2017-01-01

Measuring voltage-current and voltage-power curves of a photovoltaic module is a nice experiment for high school and undergraduate students. In labs where real sunlight is not available this experiment requires a solar simulator. A prototype of a simulator using LED lamps has been manufactured and tested, and a comparison with classical halogen…

Comprehensive clone screening and evaluation of fed-batch strategies in a microbioreactor and lab scale stirred tank bioreactor system: application on Pichia pastoris producing Rhizopus oryzae lipase

PubMed Central

2014-01-01

Background In Pichia pastoris bioprocess engineering, classic approaches for clone selection and bioprocess optimization at small/micro scale using the promoter of the alcohol oxidase 1 gene (PAOX1), induced by methanol, present low reproducibility leading to high time and resource consumption. Results An automated microfermentation platform (RoboLector) was successfully tested to overcome the chronic problems of clone selection and optimization of fed-batch strategies. Different clones from Mut+P. pastoris phenotype strains expressing heterologous Rhizopus oryzae lipase (ROL), including a subset also overexpressing the transcription factor HAC1, were tested to select the most promising clones. The RoboLector showed high performance for the selection and optimization of cultivation media with minimal cost and time. Syn6 medium was better than conventional YNB medium in terms of production of heterologous protein. The RoboLector microbioreactor was also tested for different fed-batch strategies with three clones producing different lipase levels. Two mixed substrates fed-batch strategies were evaluated. The first strategy was the enzymatic release of glucose from a soluble glucose polymer by a glucosidase, and methanol addition every 24 hours. The second strategy used glycerol as co-substrate jointly with methanol at two different feeding rates. The implementation of these simple fed-batch strategies increased the levels of lipolytic activity 80-fold compared to classical batch strategies used in clone selection. Thus, these strategies minimize the risk of errors in the clone selection and increase the detection level of the desired product. Finally, the performance of two fed-batch strategies was compared for lipase production between the RoboLector microbioreactor and 5 liter stirred tank bioreactor for three selected clones. In both scales, the same clone ranking was achieved. Conclusion The RoboLector showed excellent performance in clone selection of P

12-year Temporal Trend in Referral Pattern and Test Results of Stress Echocardiography in a Tertiary Care Referral Center with Moderate Volume Activities and Cath-lab Facility.

PubMed

Barbieri, Andrea; Mantovani, Francesca; Bursi, Francesca; Bartolacelli, Ylenia; Manicardi, Marcella; Lauria, Maria Giulia; Boriani, Giuseppe

2018-01-01

Data on stress echocardiography (SE) time-related changes in referral patterns and diagnostic yield for detection of inducible ischemia could enhance Echo Lab quality benchmarks and performance measures. This study aims to evaluate temporal trends in SE test results among ambulatory patients with suspected or known coronary artery disease (CAD) in a tertiary care referral center with moderate (>100/year) volume SE activities and Cath-Lab facility. From January 2004 to December 2015, 1954 patients (mean age 62 ± 12 years, 42% women, 27% with known CAD) underwent SE (1673 exercise SE, 86%, 246 pharmacological SE, 12%, 35 pacing SE, 2%). Time was grouped into three 4 year periods, where clinical data and test results were evaluated. Our series comprised low-to-intermediate pretest probability of CAD throughout the observation period (overall pretest probability of CAD 19% ± 15%). A progressive decline over time in the rate of pharmacological SE instead of a dramatic increment of exercise SE (79%-96%, P < 0.0001) was noted. The use of beta-blockers increased (from 43% to 66%, P < 0.0001), while the use of nitrates decreased (from 11% to 4%, P < 0.0001) over time. We noted a very uncommon occurrence of abnormal test results with a further decrease in the last period (from 11% to 3%, P < 0.0001). We observed, over a 12-year period, a progressive decrease in the frequency of inducible myocardial ischemia among patients with known or suspected CADe referred to our Echo Lab for SE with Cath-Lab facility, and this trend was parallel to changes in SE referral practice. These findings are particularly relevant if we consider the practical implications on diagnostic SE accuracy and risk assessment.

Online versus in the Classroom: Student Success in a Hands-On Lab Class

ERIC Educational Resources Information Center

Reuter, Ron

2009-01-01

This study compares learning success of online and on-campus students in a general education soil science course with lab and field components. Two terms of students completed standardized pre- and postassessments designed to test knowledge and skills from the lecture and lab content of the course. There was no difference in overall grade or lab…

Effects of granular activated carbon on methane removal performance and methanotrophic community of a lab-scale bioreactor.

PubMed

Lee, Eun-Hee; Choi, Sun-Ah; Yi, Taewoo; Kim, Tae Gwan; Lee, Sang-Don; Cho, Kyung-Suk

2015-01-01

Two identical lab-scale bioreactor systems were operated to examine the effects of granular activated carbon (GAC) on methane removal performance and methanotrophic community. Both bioreactor systems removed methane completely at a CH4 loading rate of 71.2 g-CH4·d(-1) for 17 days. However, the methane removal efficiency declined to 88% in the bioreactor without GAC, while the bioreactor amended with GAC showed greater methane removal efficiency of 97% at a CH4 loading rate of 107.5 g-CH4·d(-1). Although quantitative real-time PCR showed that methanotrophic populations were similar levels of 5-10 × 10(8) pmoA gene copy number·VSS(-1) in both systems, GAC addition changed the methanotrophic community composition of the bioreactor systems. Microarray assay revealed that GAC enhanced the type I methanotrophic genera including Methylobacter, Methylomicrobium, and Methylomonas of the system, which suggests that GAC probably provided a favorable environment for type I methanotrophs. These results indicated that GAC is a promising support material in bioreactor systems for CH4 mitigation.

Enhancing recovery of recombinant hepatitis B surface antigen in lab-scale and large-scale anion-exchange chromatography by optimizing the conductivity of buffers.

PubMed

Mojarrad Moghanloo, Gol Mohammad; Khatami, Maryam; Javidanbardan, Amin; Hosseini, Seyed Nezamedin

2018-01-01

In biopharmaceutical science, ion-exchange chromatography (IEC) is a well-known purification technique to separate the impurities such as host cell proteins from recombinant proteins. However, IEC is one of the limiting steps in the purification process of recombinant hepatitis B surface antigen (rHBsAg), due to its low recovery rate (<50%). In the current study, we hypothesized that ionic strengths of IEC buffers are easy-to-control parameters which can play a major role in optimizing the process and increasing the recovery. Thus, we investigated the effects of ionic strengths of buffers on rHBsAg recovery via adjusting Tris-HCl and NaCl concentrations. Increasing the conductivity of equilibration (Eq.), washing (Wash.) and elution (Elut.) buffers from their initial values of 1.6 mS/cm, 1.6 mS/cm, and 7.0 mS/cm to 1.6 mS/cm, 7 mS/cm and 50 mS/cm, respectively yielded an average recovery rate of 82% in both lab-scale and large-scale weak anion-exchange chromatography without any harsh effect on the purity percentage of rHBsAg. The recovery enhancement via increasing the conductivity of Eq. and Wash. buffers can be explained by their roles in reducing the binding strength and aggregation of retained particles in the column. Moreover, further increase in the salt concentration of Elut. Buffer could substantially promote the ion exchange process and the elution of retained rHBsAg. Copyright © 2017 Elsevier Inc. All rights reserved.

Developing Avionics Hardware and Software for Rocket Engine Testing

NASA Technical Reports Server (NTRS)

Aberg, Bryce Robert

2014-01-01

My summer was spent working as an intern at Kennedy Space Center in the Propulsion Avionics Branch of the NASA Engineering Directorate Avionics Division. The work that I was involved with was part of Rocket University's Project Neo, a small scale liquid rocket engine test bed. I began by learning about the layout of Neo in order to more fully understand what was required of me. I then developed software in LabView to gather and scale data from two flowmeters and integrated that code into the main control software. Next, I developed more LabView code to control an igniter circuit and integrated that into the main software, as well. Throughout the internship, I performed work that mechanics and technicians would do in order to maintain and assemble the engine.

Principles and Practice of Scaled Difference Chi-Square Testing

ERIC Educational Resources Information Center

Bryant, Fred B.; Satorra, Albert

2012-01-01

We highlight critical conceptual and statistical issues and how to resolve them in conducting Satorra-Bentler (SB) scaled difference chi-square tests. Concerning the original (Satorra & Bentler, 2001) and new (Satorra & Bentler, 2010) scaled difference tests, a fundamental difference exists in how to compute properly a model's scaling correction…

Experience in Evaluating AAL Solutions in Living Labs

PubMed Central

Colomer, Juan Bautista Montalvá; Salvi, Dario; Cabrera-Umpierrez, Maria Fernanda; Arredondo, Maria Teresa; Abril, Patricia; Jimenez-Mixco, Viveca; García-Betances, Rebeca; Fioravanti, Alessio; Pastorino, Matteo; Cancela, Jorge; Medrano, Alejandro

2014-01-01

Ambient assisted living (AAL) is a complex field, where different technologies are integrated to offer solutions for the benefit of different stakeholders. Several evaluation techniques are commonly applied that tackle specific aspects of AAL; however, holistic evaluation approaches are lacking when addressing the needs of both developers and end-users. Living labs have been often used as real-life test and experimentation environments for co-designing AAL technologies and validating them with relevant stakeholders. During the last five years, we have been evaluating AAL systems and services in the framework of various research projects. This paper presents the lessons learned in this experience and proposes a set of harmonized guidelines to conduct evaluations in living labs. PMID:24763209

Design and Testing of Scaled Ejector-Diffusers for Jet Engine Test Facility Applications.

DTIC Science & Technology

1983-09-01

the test cell such that the exhaust will be vented into an augmenting tube which acts as an ejector -diffuser assembly. 11 The kinetic energy of the...OF STANDARDS-1963-A ..’I -Dy , - 77 *4********* Z 7.77- NAVAL POSTGRADUATE SCHOOL Monterey, California W I THESIS DESIGN AND TESTING OF SCALED EJECTOR ...PERIOD COVERED Design and Testing of Scaled Ejector - "flglfeerls Thesis~ Diffusers for Jet Engine Test Facility Spebr18 S. PERFORMING ORG. REPORT

A Comparison of Laboratory and Clinical Working Memory Tests and Their Prediction of Fluid Intelligence

PubMed Central

Shelton, Jill T.; Elliott, Emily M.; Hill, B. D.; Calamia, Matthew R.; Gouvier, Wm. Drew

2010-01-01

The working memory (WM) construct is conceptualized similarly across domains of psychology, yet the methods used to measure WM function vary widely. The present study examined the relationship between WM measures used in the laboratory and those used in applied settings. A large sample of undergraduates completed three laboratory-based WM measures (operation span, listening span, and n-back), as well as the WM subtests from the Wechsler Adult Intelligence Scale-III and the Wechsler Memory Scale-III. Performance on all of the WM subtests of the clinical batteries shared positive correlations with the lab measures; however, the Arithmetic and Spatial Span subtests shared lower correlations than the other WM tests. Factor analyses revealed that a factor comprising scores from the three lab WM measures and the clinical subtest, Letter-Number Sequencing (LNS), provided the best measurement of WM. Additionally, a latent variable approach was taken using fluid intelligence as a criterion construct to further discriminate between the WM tests. The results revealed that the lab measures, along with the LNS task, were the best predictors of fluid abilities. PMID:20161647

From e-manufacturing to Internet Product Process Development (IPPD) through remote - labs

NASA Astrophysics Data System (ADS)

Córdoba Nieto, Ernesto; Andres Cifuentes Parra, Paulo; Camilo Parra Díaz, Juan

2014-07-01

This paper presents the research developed at Universidad Nacional de Colombia about the e-Manufacturing platform that is being developed and implemented at LabFabEx (acronym in Spanish as "Laboratorio Fabrica Experimental"). This platform besides has an approach to virtual-remote labs that have been tested by several students and engineers of different industrial fields. At this paper it is shown the physical and communication experimental platform, the general scope and characteristics of this e-Manufacturing platform and the virtual lab approach. This research project is funded by COLCIENCIAS (Administrative Department of science, technology and innovation in Colombia) and the enterprise IMOCOM S.A.

GeneLab: A Systems Biology Platform for Spaceflight Omics Data

NASA Technical Reports Server (NTRS)

Reinsch, Sigrid S.; Lai, San-Huei; Chen, Rick; Thompson, Terri; Berrios, Daniel; Fogle, Homer; Marcu, Oana; Timucin, Linda; Chakravarty, Kaushik; Coughlan, Joseph

2015-01-01

NASA's mission includes expanding our understanding of biological systems to improve life on Earth and to enable long-duration human exploration of space. Resources to support large numbers of spaceflight investigations are limited. NASA's GeneLab project is maximizing the science output from these experiments by: (1) developing a unique public bioinformatics database that includes space bioscience relevant "omics" data (genomics, transcriptomics, proteomics, and metabolomics) and experimental metadata; (2) partnering with NASA-funded flight experiments through bio-sample sharing or sample augmentation to expedite omics data input to the GeneLab database; and (3) developing community-driven reference flight experiments. The first database, GeneLab Data System Version 1.0, went online in April 2015. V1.0 contains numerous flight datasets and has search and download capabilities. Version 2.0 will be released in 2016 and will link to analytic tools. In 2015 Genelab partnered with two Biological Research in Canisters experiments (BBRIC-19 and BRIC-20) which examine responses of Arabidopsis thaliana to spaceflight. GeneLab also partnered with Rodent Research-1 (RR1), the maiden flight to test the newly developed rodent habitat. GeneLab developed protocols for maxiumum yield of RNA, DNA and protein from precious RR-1 tissues harvested and preserved during the SpaceX-4 mission, as well as from tissues from mice that were frozen intact during spaceflight and later dissected. GeneLab is establishing partnerships with at least three planned flights for 2016. Organism-specific nationwide Science Definition Teams (SDTs) will define future GeneLab dedicated missions and ensure the broader scientific impact of the GeneLab missions. GeneLab ensures prompt release and open access to all high-throughput omics data from spaceflight and ground-based simulations of microgravity and radiation. Overall, GeneLab will facilitate the generation and query of parallel multi-omics data, and

Lab-on-a-Chip Pathogen Sensors for Food Safety

PubMed Central

Yoon, Jeong-Yeol; Kim, Bumsang

2012-01-01

There have been a number of cases of foodborne illness among humans that are caused by pathogens such as Escherichia coli O157:H7, Salmonella typhimurium, etc. The current practices to detect such pathogenic agents are cell culturing, immunoassays, or polymerase chain reactions (PCRs). These methods are essentially laboratory-based methods that are not at all real-time and thus unavailable for early-monitoring of such pathogens. They are also very difficult to implement in the field. Lab-on-a-chip biosensors, however, have a strong potential to be used in the field since they can be miniaturized and automated; they are also potentially fast and very sensitive. These lab-on-a-chip biosensors can detect pathogens in farms, packaging/processing facilities, delivery/distribution systems, and at the consumer level. There are still several issues to be resolved before applying these lab-on-a-chip sensors to field applications, including the pre-treatment of a sample, proper storage of reagents, full integration into a battery-powered system, and demonstration of very high sensitivity, which are addressed in this review article. Several different types of lab-on-a-chip biosensors, including immunoassay- and PCR-based, have been developed and tested for detecting foodborne pathogens. Their assay performance, including detection limit and assay time, are also summarized. Finally, the use of optical fibers or optical waveguide is discussed as a means to improve the portability and sensitivity of lab-on-a-chip pathogen sensors. PMID:23112625

A catch-up validation study of an in vitro skin irritation test method using reconstructed human epidermis LabCyte EPI-MODEL24.

PubMed

Kojima, Hajime; Katoh, Masakazu; Shinoda, Shinsuke; Hagiwara, Saori; Suzuki, Tamie; Izumi, Runa; Yamaguchi, Yoshihiro; Nakamura, Maki; Kasahawa, Toshihiko; Shibai, Aya

2014-07-01

Three validation studies were conducted by the Japanese Society for Alternatives to Animal Experiments in order to assess the performance of a skin irritation assay using reconstructed human epidermis (RhE) LabCyte EPI-MODEL24 (LabCyte EPI-MODEL24 SIT) developed by the Japan Tissue Engineering Co., Ltd. (J-TEC), and the results of these studies were submitted to the Organisation for Economic Co-operation and Development (OECD) for the creation of a Test Guideline (TG). In the summary review report from the OECD, the peer review panel indicated the need to resolve an issue regarding the misclassification of 1-bromohexane. To this end, a rinsing operation intended to remove exposed chemicals was reviewed and the standard operating procedure (SOP) revised by J-TEC. Thereafter, in order to confirm general versatility of the revised SOP, a new validation management team was organized by the Japanese Center for the Validation of Alternative Methods (JaCVAM) to undertake a catch-up validation study that would compare the revised assay with similar in vitro skin irritation assays, per OECD TG No. 439 (2010). The catch-up validation and supplementary studies for LabCyte EPI-MODEL24 SIT using the revised SOPs were conducted at three laboratories. These results showed that the revised SOP of LabCyte EPI-MODEL24 SIT conformed more accurately to the classifications for skin irritation under the United Nations Globally Harmonised System of Classification and Labelling of Chemicals (UN GHS), thereby highlighting the importance of an optimized rinsing operation for the removal of exposed chemicals in obtaining consistent results from in vitro skin irritation assays. Copyright © 2013 John Wiley & Sons, Ltd.

GeneLab: Open Science For Exploration

NASA Technical Reports Server (NTRS)

Galazka, Jonathan

2018-01-01

The NASA GeneLab project capitalizes on multi-omic technologies to maximize the return on spaceflight experiments. The GeneLab project houses spaceflight and spaceflight-relevant multi-omics data in a publicly accessible data commons, and collaborates with NASA-funded principal investigators to maximize the omics data from spaceflight and spaceflight-relevant experiments. I will discuss the current status of GeneLab and give specific examples of how the GeneLab data system has been used to gain insight into how biology responds to spaceflight conditions.

Enhancing pre-service physics teachers' creative thinking skills through HOT lab design

NASA Astrophysics Data System (ADS)

Malik, Adam; Setiawan, Agus; Suhandi, Andi; Permanasari, Anna

2017-08-01

A research on the implementation of HOT (Higher Order Thinking) Laboratory has been carried out. This research is aimed to compare increasing of creative thinking skills of pre-service physics teachers who receive physics lesson with HOT Lab and with verification lab for the topic of electric circuit. This research used a quasi-experiment methods with control group pretest-posttest design. The subject of the research is 40 Physics Education pre-service physics teachers of UIN Sunan Gunung Djati Bandung. Research samples were selected by class random sampling technique. Data on pre-service physics teachers' creative thinking skills were collected using test of creative thinking skills in the form of essay. The results of the research reveal that average of N-gain of creative thinking skills are <0,69> for pre-service physics teachers who received lesson with HOT Lab design and <0,39> for pre-service physics teachers who received lesson with verification lab, respectively. Therefore, we conclude that application of HOT Lab design is more effective to increase creative thinking skills in the lesson of electric circuit.

Goethite Bench-scale and Large-scale Preparation Tests

DOE Office of Scientific and Technical Information (OSTI.GOV)

Josephson, Gary B.; Westsik, Joseph H.

2011-10-23

The Hanford Waste Treatment and Immobilization Plant (WTP) is the keystone for cleanup of high-level radioactive waste from our nation's nuclear defense program. The WTP will process high-level waste from the Hanford tanks and produce immobilized high-level waste glass for disposal at a national repository, low activity waste (LAW) glass, and liquid effluent from the vitrification off-gas scrubbers. The liquid effluent will be stabilized into a secondary waste form (e.g. grout-like material) and disposed on the Hanford site in the Integrated Disposal Facility (IDF) along with the low-activity waste glass. The major long-term environmental impact at Hanford results from technetiummore » that volatilizes from the WTP melters and finally resides in the secondary waste. Laboratory studies have indicated that pertechnetate ({sup 99}TcO{sub 4}{sup -}) can be reduced and captured into a solid solution of {alpha}-FeOOH, goethite (Um 2010). Goethite is a stable mineral and can significantly retard the release of technetium to the environment from the IDF. The laboratory studies were conducted using reaction times of many days, which is typical of environmental subsurface reactions that were the genesis of this new process. This study was the first step in considering adaptation of the slow laboratory steps to a larger-scale and faster process that could be conducted either within the WTP or within the effluent treatment facility (ETF). Two levels of scale-up tests were conducted (25x and 400x). The largest scale-up produced slurries of Fe-rich precipitates that contained rhenium as a nonradioactive surrogate for {sup 99}Tc. The slurries were used in melter tests at Vitreous State Laboratory (VSL) to determine whether captured rhenium was less volatile in the vitrification process than rhenium in an unmodified feed. A critical step in the technetium immobilization process is to chemically reduce Tc(VII) in the pertechnetate (TcO{sub 4}{sup -}) to Tc(Iv)by reaction with the

Replication of engine block cylinder bridge microstructure and mechanical properties with lab scale 319 Al alloy billet castings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lombardi, A., E-mail: a2lombar@ryerson.ca; D'Elia, F.; Ravindran, C.

2014-01-15

In recent years, aluminum alloy gasoline engine blocks have in large part successfully replaced nodular cast iron engine blocks, resulting in improved vehicle fuel efficiency. However, because of the inadequate wear resistance properties of hypoeutectic Al–Si alloys, gray iron cylinder liners are required. These liners cause the development of large tensile residual stress along the cylinder bores and necessitate the maximization of mechanical properties in this region to prevent premature engine failure. The aim of this study was to replicate the engine cylinder bridge microstructure and mechanical properties following TSR treatment (which removes the sand binder to enable easy castingmore » retrieval) using lab scale billet castings of the same alloy composition with varying cooling rates. Comparisons in microstructure between the engine block and the billet castings were carried out using optical and scanning electron microscopy, while mechanical properties were assessed using tensile testing. The results suggest that the microstructure at the top and middle of the engine block cylinder bridge was successfully replicated by the billet castings. However, the microstructure at the bottom of the cylinder was not completely replicated due to variations in secondary phase morphology and distribution. The successful replication of engine block microstructure will enable the future optimization of heat treatment parameters. - Highlights: • A method to replicate engine block microstructure was developed. • Billet castings will allow cost effective optimization of heat treatment process. • The replication of microstructure in the cylinder region was mostly successful. • Porosity was more clustered in the billet castings compared to the engine block. • Mechanical properties were lower in billet castings due to porosity and inclusions.« less

A Museum Learning Lab

ERIC Educational Resources Information Center

Vandiver, Kathleen M.; Bijur, Jon Markowitz; Epstein, Ari W.; Rosenthal, Beryl; Stidsen, Don

2008-01-01

The "Learning Lab: The Cell" exhibit was developed by the Massachusetts Institute of Technology (MIT) Museum and the MIT Center for Environmental Health Sciences (CEHS). Specially designed for middle and high school students, the Learning Lab provides museum visitors of all ages with fascinating insights into how our living cells work. The…

Final Assembly and Factory Testing of the Jefferson Lab SHMS Spectrometer Quadrupole and Dipole Superconducting Magnets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brindza, Paul; Lassiter, Steven; Sun, Eric

Jefferson Lab is constructing an 11 Gev/c electron spectrometer called the Super High Momentum Spectrometer (SHMS) as part of the 12 GeV JLAB upgrade for experimental Hall C. Three of the five superconducting(SC) SHMS magnets are under construction at SigmaPhi in Vannes France as a result of an international competition for design and fabrication. The three magnets Q2 and Q3 60 cm bore quadrupoles and the 60 cm warm bore dipole are complete or near complete and have many design features in common. All three magnets share a common superconductor, collaring system, cryostat design, cold to warm support, cryogenic interface,more » burnout resistant current leads, DC power supply, quench protection, instrumentation and controls. The three magnets are collared, installed in cryostats and welded up and in various stages of final testing. The Q2 quadrupole is due to ship from France to America in August arriving during this ASC conference and has passed all final hipot, leak and pressure tests. The dipole is in leak and pressure testing as of July 2016 while the Q3 quadrupole requires some outer vacuum vessel assembly. Delivery of the Q3 and Dipole magnets will follow the Q2 at about 1 month intervals. Lastly, factory testing have included hipot and electrical tests, magnetic tests at low field, mechanical alignments to center the coils, leak tests and ASME Code required pressure tests. Upon installation in Hall C at JLAB cold testing will commence.« less

Final Assembly and Factory Testing of the Jefferson Lab SHMS Spectrometer Quadrupole and Dipole Superconducting Magnets

DOE PAGES

Brindza, Paul; Lassiter, Steven; Sun, Eric; ...

2017-06-01

Jefferson Lab is constructing an 11 Gev/c electron spectrometer called the Super High Momentum Spectrometer (SHMS) as part of the 12 GeV JLAB upgrade for experimental Hall C. Three of the five superconducting(SC) SHMS magnets are under construction at SigmaPhi in Vannes France as a result of an international competition for design and fabrication. The three magnets Q2 and Q3 60 cm bore quadrupoles and the 60 cm warm bore dipole are complete or near complete and have many design features in common. All three magnets share a common superconductor, collaring system, cryostat design, cold to warm support, cryogenic interface,more » burnout resistant current leads, DC power supply, quench protection, instrumentation and controls. The three magnets are collared, installed in cryostats and welded up and in various stages of final testing. The Q2 quadrupole is due to ship from France to America in August arriving during this ASC conference and has passed all final hipot, leak and pressure tests. The dipole is in leak and pressure testing as of July 2016 while the Q3 quadrupole requires some outer vacuum vessel assembly. Delivery of the Q3 and Dipole magnets will follow the Q2 at about 1 month intervals. Lastly, factory testing have included hipot and electrical tests, magnetic tests at low field, mechanical alignments to center the coils, leak tests and ASME Code required pressure tests. Upon installation in Hall C at JLAB cold testing will commence.« less

Near Space Lab-Rat Experimentation using Stratospheric Balloon

NASA Astrophysics Data System (ADS)

Buduru, Suneel Kumar; Reddy Vizapur, Anmi; Rao Tanneeru, Venkateswara; Trivedi, Dharmesh; Devarajan, Anand; Pandit Manikrao Kulkarni, MR..; Ojha, Devendra; Korra, Sakram; Neerudu, Nagendra; Seng, Lim; Godi, Stalin Peter

2016-07-01

First ever balloon borne lab-rat experiment up to near space stratospheric altitude levels carried out at TIFR Balloon Facility, Hydeabad using zero pressure balloons for the purpose of validating the life support system. A series of two balloon experiments conducted under joint collaboration with IN.Genius, Singapore in the year 2015. In these experiments, three lab-rats sent to stratosphere in a pressurized capsule designed to reach an altitude of 30 km by keeping constant pressure, temperature and maintained at a precise rate of oxygen supply inside the capsule. The first experiment conducted on 1 ^{st} February, 2015 with a total suspended weight of 225 kg. During the balloon ascent stage at 18 km altitude, sensors inside the capsule reported drastic drop in internal pressure while oxygen and temperatures maintained at correct levels resulted in premature fligt termination at 20.1 km. All the three lab-rats recovered without life due to the collapse of their lungs caused by the depressurization inside the capsule. The second experiment conducted on 14th March, 2015 using a newly developed capsule with rectification of depressurization fault by using improved sealing gaskets and hermitically sealed connectors for sending lab-rats again to stratosphere comprising a total suspended load of 122.3 kg. The balloon flight was terminated after reaching 29.5 km in 110 minutes and succesfully recovered all the three lab-rats alive. This paper focuses on lessons learnt of the development of the life support system as an integral pressurized vessel, flight control instrumentation, flight simulation tests using thermo-vaccum chamber with pre-flight operations.

The LabTube - a novel microfluidic platform for assay automation in laboratory centrifuges.

PubMed

Kloke, A; Fiebach, A R; Zhang, S; Drechsel, L; Niekrawietz, S; Hoehl, M M; Kneusel, R; Panthel, K; Steigert, J; von Stetten, F; Zengerle, R; Paust, N

2014-05-07

Assay automation is the key for successful transformation of modern biotechnology into routine workflows. Yet, it requires considerable investment in processing devices and auxiliary infrastructure, which is not cost-efficient for laboratories with low or medium sample throughput or point-of-care testing. To close this gap, we present the LabTube platform, which is based on assay specific disposable cartridges for processing in laboratory centrifuges. LabTube cartridges comprise interfaces for sample loading and downstream applications and fluidic unit operations for release of prestored reagents, mixing, and solid phase extraction. Process control is achieved by a centrifugally-actuated ballpen mechanism. To demonstrate the workflow and functionality of the LabTube platform, we show two LabTube automated sample preparation assays from laboratory routines: DNA extractions from whole blood and purification of His-tagged proteins. Equal DNA and protein yields were observed compared to manual reference runs, while LabTube automation could significantly reduce the hands-on-time to one minute per extraction.

Bacteria Culture Test: MedlinePlus Lab Test Information

MedlinePlus

... Information → Bacteria Culture Test URL of this page: https://medlineplus.gov/labtests/bacteriaculturetest.html Bacteria Culture Test ... 2017 Mar 4]; [about 3 screens]. Available from: https://labtestsonline.org/understanding/analytes/sputum-culture/tab/test/ ...

Blood Glucose Test: MedlinePlus Lab Test Information

MedlinePlus

... https://medlineplus.gov/labtests/bloodglucosetest.html Blood Glucose Test To use the sharing features on this page, please enable JavaScript. What is a Blood Glucose Test? A blood glucose test measures the glucose levels ...

Chloride Blood Test: MedlinePlus Lab Test Information

MedlinePlus

... https://medlineplus.gov/labtests/chloridebloodtest.html Chloride Blood Test To use the sharing features on this page, please enable JavaScript. What is a Chloride Blood Test? A chloride blood test measures the amount of ...

Bilirubin Blood Test: MedlinePlus Lab Test Information

MedlinePlus

... https://medlineplus.gov/labtests/bilirubinbloodtest.html Bilirubin Blood Test To use the sharing features on this page, please enable JavaScript. What is a Bilirubin Blood Test? A bilirubin blood test measures the levels of ...

Potassium Blood Test: MedlinePlus Lab Test Information

MedlinePlus

... https://medlineplus.gov/labtests/potassiumbloodtest.html Potassium Blood Test To use the sharing features on this page, please enable JavaScript. What is a Potassium Blood Test? A potassium blood test measures the amount of ...

Prealbumin Blood Test: MedlinePlus Lab Test Information

MedlinePlus

... https://medlineplus.gov/labtests/prealbuminbloodtest.html Prealbumin Blood Test To use the sharing features on this page, please enable JavaScript. What is a prealbumin blood test? A prealbumin blood test measures prealbumin levels in ...

Ferritin Blood Test: MedlinePlus Lab Test Information

MedlinePlus

... https://medlineplus.gov/labtests/ferritinbloodtest.html Ferritin Blood Test To use the sharing features on this page, please enable JavaScript. What is a Ferritin Blood Test? A ferritin blood test measures the level of ...

30 CFR 14.21 - Laboratory-scale flame test apparatus.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Laboratory-scale flame test apparatus. 14.21 Section 14.21 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING... Technical Requirements § 14.21 Laboratory-scale flame test apparatus. The principal parts of the apparatus...

30 CFR 14.21 - Laboratory-scale flame test apparatus.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Laboratory-scale flame test apparatus. 14.21 Section 14.21 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING... Technical Requirements § 14.21 Laboratory-scale flame test apparatus. The principal parts of the apparatus...

Performance Test on Polymer Waste Form - 12137

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Se Yup

Polymer solidification was attempted to produce stable waste form for the boric acid concentrates and the dewatered spent resins. The polymer mixture was directly injected into the mold or drum which was packed with the boric acid concentrates and the dewatered spent resins, respectively. The waste form was produced by entirely curing the polymer mixture. A series of performance tests was conducted including compressive strength test, water immersion test, leach test, thermal stability test, irradiation stability test and biodegradation stability test for the polymer waste forms. From the results of the performance tests for the polymer waste forms, it ismore » believed that the polymer waste form is very stable and can satisfy the acceptance criteria for permanent disposal. At present, performance tests with full scale polymer waste forms are being carried out in order to obtain qualification certificate by the regulatory institute in Korea. Polymer waste forms were prepared with the surrogate of boric acid concentrates and the surrogate of spent ion exchange resins respectively. Waste forms were also made in lab scale and in full scale. Lab. scale waste forms were directly subjected to a series of the performance tests. In the case of full scale waste form, the test specimens for the performance test were taken from a part of waste form by coring. A series of performance tests was conducted including compressive strength test, thermal stability test, irradiation stability test and biodegradation stability test, water immersion test, leach test, and free standing water for the polymer waste forms. In addition, a fire resistance test was performed on the waste forms by the requirement of the regulatory institute in Korea. Every polymer waste forms containing the boric acid concentrates and the spent ion exchange resins had exhibited excellent structural integrity of more than 27.58 MPa (4,000 psi) of compressive strength. On thermal stability testing

A preliminary and qualitative study of resource ratio theory to nitrifying lab-scale bioreactors.

PubMed

Bellucci, Micol; Ofiţeru, Irina D; Beneduce, Luciano; Graham, David W; Head, Ian M; Curtis, Thomas P

2015-05-01

The incorporation of microbial diversity in design would ideally require predictive theory that would relate operational parameters to the numbers and distribution of taxa. Resource ratio-theory (RRT) might be one such theory. Based on Monod kinetics, it explains diversity in function of resource-ratio and richness. However, to be usable in biological engineered system, the growth parameters of all the bacteria under consideration and the resource supply and diffusion parameters for all the relevant nutrients should be determined. This is challenging, but plausible, at least for low diversity groups with simple resource requirements like the ammonia oxidizing bacteria (AOB). One of the major successes of RRT was its ability to explain the 'paradox of enrichment' which states that diversity first increases and then decreases with resource richness. Here, we demonstrate that this pattern can be seen in lab-scale-activated sludge reactors and parallel simulations that incorporate the principles of RRT in a floc-based system. High and low ammonia and oxygen were supplied to continuous flow bioreactors with resource conditions correlating with the composition and diversity of resident AOB communities based on AOB 16S rDNA clone libraries. Neither the experimental work nor the simulations are definitive proof for the application of RRT in this context. However, it is sufficient evidence that such approach might work and justify a more rigorous investigation. © 2015 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology.

Breaking Out of the Lab

PubMed Central

Maier, Jürgen; Hampe, J. Felix; Jahn, Nico

2016-01-01

Real-time response (RTR) measurement is an important technique for analyzing human processing of electronic media stimuli. Although it has been demonstrated that RTR data are reliable and internally valid, some argue that they lack external validity. The reason for this is that RTR measurement is restricted to a laboratory environment due to its technical requirements. This paper introduces a smartphone app that 1) captures real-time responses using the dial technique and 2) provides a solution for one of the most important problems in RTR measurement, the (automatic) synchronization of RTR data. In addition, it explores the reliability and validity of mobile RTR measurement by comparing the real-time reactions of two samples of young and well-educated voters to the 2013 German televised debate. Whereas the first sample participated in a classical laboratory study, the second sample was equipped with our mobile RTR system and watched the debate at home. Results indicate that the mobile RTR system yields similar results to the lab-based RTR measurement, providing evidence that laboratory studies using RTR are externally valid. In particular, the argument that the artificial reception situation creates artificial results has to be questioned. In addition, we conclude that RTR measurement outside the lab is possible. Hence, mobile RTR opens the door for large-scale studies to better understand the processing and impact of electronic media content. PMID:27274577

Evaluation of constant-Weber-number scaling for icing tests

NASA Technical Reports Server (NTRS)

Anderson, David N.

1996-01-01

Previous studies showed that for conditions simulating an aircraft encountering super-cooled water droplets the droplets may splash before freezing. Other surface effects dependent on the water surface tension may also influence the ice accretion process. Consequently, the Weber number appears to be important in accurately scaling ice accretion. A scaling method which uses a constant-Weber-number approach has been described previously; this study provides an evaluation of this scaling method. Tests are reported on cylinders of 2.5 to 15-cm diameter and NACA 0012 airfoils with chords of 18 to 53 cm in the NASA Lewis Icing Research Tunnel (IRT). The larger models were used to establish reference ice shapes, the scaling method was applied to determine appropriate scaled test conditions using the smaller models, and the ice shapes were compared. Icing conditions included warm glaze, horn glaze and mixed. The smallest size scaling attempted was 1/3, and scale and reference ice shapes for both cylinders and airfoils indicated that the constant-Weber-number scaling method was effective for the conditions tested.

An Acoustical Comparison of Sub-Scale and Full-Scale Far-Field Measurements for the Reusable Solid Rocket Motor

NASA Technical Reports Server (NTRS)

Haynes, Jared; Kenny, R. Jeremy

2010-01-01

Recently, members of the Marshall Space Flight Center (MSFC) Fluid Dynamics Branch and Wyle Labs measured far-field acoustic data during a series of three Reusable Solid Rocket Motor (RSRM) horizontal static tests conducted in Promontory, Utah. The test motors included the Technical Evaluation Motor 13 (TEM-13), Flight Verification Motor 2 (FVM-2), and the Flight Simulation Motor 15 (FSM-15). Similar far-field data were collected during horizontal static tests of sub-scale solid rocket motors at MSFC. Far-field acoustical measurements were taken at multiple angles within a circular array centered about the nozzle exit plane, each positioned at a radial distance of 80 nozzle-exit-diameters from the nozzle. This type of measurement configuration is useful for calculating rocket noise characteristics such as those outlined in the NASA SP-8072 "Acoustic Loads Generated by the Propulsion System." Acoustical scaling comparisons are made between the test motors, with particular interest in the Overall Sound Power, Acoustic Efficiency, Non-dimensional Relative Sound Power Spectrum, and Directivity. Since most empirical data in the NASA SP-8072 methodology is derived from small rockets, this investigation provides an opportunity to check the data collapse between a sub-scale and full-scale rocket motor.

SPF Full-scale emissions test method development status ...

EPA Pesticide Factsheets

This is a non-technical presentation that is intended to inform ASTM task group members about our intended approach to full-scale emissions testing that includes the application of spray foam in an environmental chamber. The presentation describes the approach to emissions characterization, types of measurement systems employed, and expected outcomes from the planned tests. Purpose of this presentation is to update the ASTM D22.05 work group regarding status of our full-scale emissions test method development.

Development and psychometric testing of a barriers to HIV testing scale among individuals with HIV infection in Sweden; The Barriers to HIV testing scale-Karolinska version.

PubMed

Wiklander, Maria; Brännström, Johanna; Svedhem, Veronica; Eriksson, Lars E

2015-11-19

Barriers to HIV testing experienced by individuals at risk for HIV can result in treatment delay and further transmission of the disease. Instruments to systematically measure barriers are scarce, but could contribute to improved strategies for HIV testing. Aims of this study were to develop and test a barriers to HIV testing scale in a Swedish context. An 18-item scale was developed, based on an existing scale with addition of six new items related to fear of the disease or negative consequences of being diagnosed as HIV-infected. Items were phrased as statements about potential barriers with a three-point response format representing not important, somewhat important, and very important. The scale was evaluated regarding missing values, floor and ceiling effects, exploratory factor analysis, and internal consistencies. The questionnaire was completed by 292 adults recently diagnosed with HIV infection, of whom 7 were excluded (≥9 items missing) and 285 were included (≥12 items completed) in the analyses. The participants were 18-70 years old (mean 40.5, SD 11.5), 39 % were females and 77 % born outside Sweden. Routes of transmission were heterosexual transmission 63 %, male to male sex 20 %, intravenous drug use 5 %, blood product/transfusion 2 %, and unknown 9 %. All scale items had <3 % missing values. The data was feasible for factor analysis (KMO = 0.92) and a four-factor solution was chosen, based on level of explained common variance (58.64 %) and interpretability of factor structure. The factors were interpreted as; personal consequences, structural barriers, social and economic security, and confidentiality. Ratings on the minimum level (suggested barrier not important) were common, resulting in substantial floor effects on the scales. The scales were internally consistent (Cronbach's α 0.78-0.91). This study gives preliminary evidence of the scale being feasible, reliable and valid to identify different types of barriers to HIV testing.

Large-Scale Multiobjective Static Test Generation for Web-Based Testing with Integer Programming

ERIC Educational Resources Information Center

Nguyen, M. L.; Hui, Siu Cheung; Fong, A. C. M.

2013-01-01

Web-based testing has become a ubiquitous self-assessment method for online learning. One useful feature that is missing from today's web-based testing systems is the reliable capability to fulfill different assessment requirements of students based on a large-scale question data set. A promising approach for supporting large-scale web-based…

ThinkSpace: Spatial Thinking in Middle School Astronomy Labs

NASA Astrophysics Data System (ADS)

Udomprasert, Patricia S.; Goodman, Alyssa A.; Plummer, Julia; Sadler, Philip M.; Johnson, Erin; Sunbury, Susan; Zhang, Helen; Dussault, Mary E.

2016-01-01

Critical breakthroughs in science (e.g., Einstein's Theory of General Relativity, and Watson & Crick's discovery of the structure of DNA), originated with those scientists' ability to think spatially, and research has shown that spatial ability correlates strongly with likelihood of entering a career in STEM. Mounting evidence also shows that spatial skills are malleable, i.e., they can be improved through training. We report early work from a new project that will build on this research to create a series of middle schools science labs called "Thinking Spatially about the Universe" (ThinkSpace), in which students will use a blend of physical and virtual models (in WorldWide Telescope) to explore complex 3-dimensional phenomena in space science. In the three-year ThinkSpace labs project, astronomers, technologists, and education researchers are collaborating to create and test a suite of three labs designed to improve learners' spatial abilities through studies of: 1) Moon phases and eclipses; 2) planetary systems around stars other than the Sun; and 3.) celestial motions within the broader universe. The research program will determine which elements in the labs will best promote improvement of spatial skills within activities that emphasize disciplinary core ideas; and how best to optimize interactive dynamic visualizations to maximize student understanding.

DOE EiR at Oakridge National Lab 2008/09

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bauer, Michael

2012-11-30

This project placed an experienced technology entrepreneur at Oak Ridge National Lab, one of DOE's premier laboratories undertaking cutting edge research in a variety of fields, including energy technologies. With the goal of accelerating the commercialization of advanced energy technologies, the task was to review available technologies at the lab and identify those that qualify for licensing and commercialization by a private startup company, backed by private venture capital. During the project, more than 1,500 inventions filed at the lab were reviewed over a 1 year period; a successively smaller number was selected for more detailed review, ultimately resulting inmore » five, and then 1 technology, being reviewed for immediate commercialization. The chosen technology, consisting in computational chemistry based approached to optimization of enzymes, was tested in lab experiments, paid for by funds raised by ORNL for the purpose of proving out the effectiveness of the technology and readiness for commercialization. The experiments proved out that the technology worked however it's performance proved not yet mature enough to qualify for private venture capital funded commercialization in a high tech startup. As a consequence, the project did not result in a new startup company being formed, as originally intended.« less

Comparison of Test and Finite Element Analysis for Two Full-Scale Helicopter Crash Tests

NASA Technical Reports Server (NTRS)

Annett, Martin S.; Horta,Lucas G.

2011-01-01

Finite element analyses have been performed for two full-scale crash tests of an MD-500 helicopter. The first crash test was conducted to evaluate the performance of a composite deployable energy absorber under combined flight loads. In the second crash test, the energy absorber was removed to establish the baseline loads. The use of an energy absorbing device reduced the impact acceleration levels by a factor of three. Accelerations and kinematic data collected from the crash tests were compared to analytical results. Details of the full-scale crash tests and development of the system-integrated finite element model are briefly described along with direct comparisons of acceleration magnitudes and durations for the first full-scale crash test. Because load levels were significantly different between tests, models developed for the purposes of predicting the overall system response with external energy absorbers were not adequate under more severe conditions seen in the second crash test. Relative error comparisons were inadequate to guide model calibration. A newly developed model calibration approach that includes uncertainty estimation, parameter sensitivity, impact shape orthogonality, and numerical optimization was used for the second full-scale crash test. The calibrated parameter set reduced 2-norm prediction error by 51% but did not improve impact shape orthogonality.

Physics Labs with Flavor

ERIC Educational Resources Information Center

Agrest, Mikhail M.

2009-01-01

This paper describes my attempts to look deeper into the so-called "shoot for your grade" labs, started in the '90s, when I began applying my teaching experience in Russia to introductory physics labs at the College of Charleston and other higher education institutions in South Carolina. The term "shoot for your grade" became popular among…

Making Real Virtual Labs

ERIC Educational Resources Information Center

Keller, Harry E.; Keller, Edward E.

2005-01-01

Francis Bacon began defining scientific methodology in the early 17th century, and secondary school science classes began to implement science labs in the mid-19th century. By the early 20th century, leading educators were suggesting that science labs be used to develop scientific thinking habits in young students, and at the beginning of the 21st…

NOT Another Lab Report

ERIC Educational Resources Information Center

Ende, Fred

2012-01-01

Ask students to name the aspects of science class they enjoy most, and working on labs will undoubtedly be mentioned. What often won't be included, however, is writing lab reports. For many students, the process of exploration and data collection is paramount, while the explanation and analysis of findings often takes a backseat. After all, if…

1. View of EPA Farm Lab Building 1506, facing south ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. View of EPA Farm Lab Building 15-06, facing south - Nevada Test Site, Environmental Protection Agency Farm, Laboratory Building, Area 15, Yucca Flat, 10-2 Road near Circle Road, Mercury, Nye County, NV

Small-Scale Tests of MX Vertical Shelter Structures.

DTIC Science & Technology

1983-06-29

models were built with as much geometric and material similitude as practical. They 7were not identical to the 1/3-scale structures tested in the VST ...comparison with the 1/30-scale models and the 1/6-scale models, the 1/3-scale VST 7 models had different geometry (wall thickness variations), different...1/30-scale and 1/6-scale results with the 1/3-scale VST results. For example, the strains measured in the 1/3-scale ’B’ structure are about twice as

Are Virtual Labs as Effective as Hands-on Labs for Undergraduate Physics? A Comparative Study at Two Major Universities

ERIC Educational Resources Information Center

Darrah, Marjorie; Humbert, Roxann; Finstein, Jeanne; Simon, Marllin; Hopkins, John

2014-01-01

Most physics professors would agree that the lab experiences students have in introductory physics are central to the learning of the concepts in the course. It is also true that these physics labs require time and money for upkeep, not to mention the hours spent setting up and taking down labs. Virtual physics lab experiences can provide an…

Laboratory Scale Coal And Biomass To Drop-In Fuels (CBDF) Production And Assessment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lux, Kenneth; Imam, Tahmina; Chevanan, Nehru

This Final Technical Report describes the work and accomplishments of the project entitled, “Laboratory Scale Coal and Biomass to Drop-In Fuels (CBDF) Production and Assessment.” The main objective of the project was to fabricate and test a lab-scale liquid-fuel production system using coal containing different percentages of biomass such as corn stover and switchgrass at a rate of 2 liters per day. The system utilizes the patented Altex fuel-production technology, which incorporates advanced catalysts developed by Pennsylvania State University. The system was designed, fabricated, tested, and assessed for economic and environmental feasibility relative to competing technologies.

Evolution of language: An empirical study at eBay Big Data Lab.

PubMed

Bodoff, David; Bekkerman, Ron; Dai, Julie

2017-01-01

The evolutionary theory of language predicts that a language will tend towards fewer synonyms for a given object. We subject this and related predictions to empirical tests, using data from the eBay Big Data Lab which let us access all records of the words used by eBay vendors in their item titles, and by consumers in their searches. We find support for the predictions of the evolutionary theory of language. In particular, the mapping from object to words sharpens over time on both sides of the market, i.e. among consumers and among vendors. In addition, the word mappings used on the two sides of the market become more similar over time. Our research contributes to the literature on language evolution by reporting results of a truly unique large-scale empirical study.

Berkeley Lab - Materials Sciences Division

Science.gov Websites

Berkeley Lab Berkeley Lab A-Z Index Phone Book Jobs Search DOE Search MSD Go MSD - Materials Investigators Division Staff Facilities and Centers Staff Jobs Safety Personnel Resources Committees In Case of

Chip in a lab: Microfluidics for next generation life science research

PubMed Central

Streets, Aaron M.; Huang, Yanyi

2013-01-01

Microfluidic circuits are characterized by fluidic channels and chambers with a linear dimension on the order of tens to hundreds of micrometers. Components of this size enable lab-on-a-chip technology that has much promise, for example, in the development of point-of-care diagnostics. Micro-scale fluidic circuits also yield practical, physical, and technological advantages for studying biological systems, enhancing the ability of researchers to make more precise quantitative measurements. Microfluidic technology has thus become a powerful tool in the life science research laboratory over the past decade. Here we focus on chip-in-a-lab applications of microfluidics and survey some examples of how small fluidic components have provided researchers with new tools for life science research. PMID:23460772

LLNL Small-Scale Friction sensitivity (BAM) Test

DOE Office of Scientific and Technical Information (OSTI.GOV)

Simpson, L.R.; Foltz, M.F.

1996-06-01

Small-scale safety testing of explosives, propellants and other energetic materials, is done to determine their sensitivity to various stimuli including friction, static spark, and impact. Testing is done to discover potential handling problems for either newly synthesized materials of unknown behavior, or materials that have been stored for long periods of time. This report describes the existing {open_quotes}BAM{close_quotes} Small-Scale Friction Test, and the methods used to determine the friction sensitivity pertinent to handling energetic materials. The accumulated data for the materials tested is not listed here - that information is in a database. Included is, however, a short list ofmore » (1) materials that had an unusual response, and (2), a few {open_quotes}standard{close_quotes} materials representing the range of typical responses usually seen.« less

Enhancing Communication Skills of Pre-service Physics Teacher through HOT Lab Related to Electric Circuit

NASA Astrophysics Data System (ADS)

Malik, A.; Setiawan, A.; Suhandi, A.; Permanasari, A.; Dirgantara, Y.; Yuniarti, H.; Sapriadil, S.; Hermita, N.

2018-01-01

This study aimed to investigate the improvement to pre-service teacher’s communication skills through Higher Order Thinking Laboratory (HOT Lab) on electric circuit topic. This research used the quasi-experiment method with pretest-posttest control group design. Research subjects were 60 students of Physics Education in UIN Sunan Gunung Djati Bandung. The sample was chosen by random sampling technique. Students’ communication skill data collected using a communication skills test instruments-essays form and observations sheets. The results showed that pre-service teacher communication skills using HOT Lab were higher than verification lab. Student’s communication skills in groups using HOT Lab were not influenced by gender. Communication skills could increase due to HOT Lab based on problems solving that can develop communication through hands-on activities. Therefore, the conclusion of this research shows the application of HOT Lab is more effective than the verification lab to improve communication skills of pre-service teachers in electric circuit topic and gender is not related to a person’s communication skills.

Furniture wood wastes: Experimental property characterisation and burning tests

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tatano, Fabio; Barbadoro, Luca; Mangani, Giovanna

2009-10-15

Referring to the industrial wood waste category (as dominant in the provincial district of Pesaro-Urbino, Marche Region, Italy), this paper deals with the experimental characterisation and the carrying out of non-controlled burning tests (at lab- and pilot-scale) for selected 'raw' and primarily 'engineered' ('composite') wood wastes. The property characterisation has primarily revealed the following aspects: potential influence on moisture content of local weather conditions at outdoor wood waste storage sites; generally, higher ash contents in 'engineered' wood wastes as compared with 'raw' wood wastes; and relatively high energy content values of 'engineered' wood wastes (ranging on the whole from 3675more » to 5105 kcal kg{sup -1} for HHV, and from 3304 to 4634 kcal kg{sup -1} for LHV). The smoke qualitative analysis of non-controlled lab-scale burning tests has primarily revealed: the presence of specific organic compounds indicative of incomplete wood combustion; the presence exclusively in 'engineered' wood burning tests of pyrroles and amines, as well as the additional presence (as compared with 'raw' wood burning) of further phenolic and containing nitrogen compounds; and the potential environmental impact of incomplete industrial wood burning on the photochemical smog phenomenon. Finally, non-controlled pilot-scale burning tests have primarily given the following findings: emission presence of carbon monoxide indicative of incomplete wood combustion; higher nitrogen oxide emission values detected in 'engineered' wood burning tests as compared with 'raw' wood burning test; and considerable generation of the respirable PM{sub 1} fraction during incomplete industrial wood burning.« less

Labs That Are a Blast.

ERIC Educational Resources Information Center

Hendrix, Laura

1996-01-01

Presents activities that use a simple homemade apparatus called "the cannon" to demonstrate Newton's Third Law. Reviews the chemistry concepts behind the ignition of the cannon and presents the Momentum Lab and the Projectile Motion Lab. (JRH)

RoboLab and virtual environments

NASA Technical Reports Server (NTRS)

Giarratano, Joseph C.

1994-01-01

A useful adjunct to the manned space station would be a self-contained free-flying laboratory (RoboLab). This laboratory would have a robot operated under telepresence from the space station or ground. Long duration experiments aboard RoboLab could be performed by astronauts or scientists using telepresence to operate equipment and perform experiments. Operating the lab by telepresence would eliminate the need for life support such as food, water and air. The robot would be capable of motion in three dimensions, have binocular vision TV cameras, and two arms with manipulators to simulate hands. The robot would move along a two-dimensional grid and have a rotating, telescoping periscope section for extension in the third dimension. The remote operator would wear a virtual reality type headset to allow the superposition of computer displays over the real-time video of the lab. The operators would wear exoskeleton type arms to facilitate the movement of objects and equipment operation. The combination of video displays, motion, and the exoskeleton arms would provide a high degree of telepresence, especially for novice users such as scientists doing short-term experiments. The RoboLab could be resupplied and samples removed on other space shuttle flights. A self-contained RoboLab module would be designed to fit within the cargo bay of the space shuttle. Different modules could be designed for specific applications, i.e., crystal-growing, medicine, life sciences, chemistry, etc. This paper describes a RoboLab simulation using virtual reality (VR). VR provides an ideal simulation of telepresence before the actual robot and laboratory modules are constructed. The easy simulation of different telepresence designs will produce a highly optimum design before construction rather than the more expensive and time consuming hardware changes afterwards.

AnimatLab: a 3D graphics environment for neuromechanical simulations.

PubMed

Cofer, David; Cymbalyuk, Gennady; Reid, James; Zhu, Ying; Heitler, William J; Edwards, Donald H

2010-03-30

The nervous systems of animals evolved to exert dynamic control of behavior in response to the needs of the animal and changing signals from the environment. To understand the mechanisms of dynamic control requires a means of predicting how individual neural and body elements will interact to produce the performance of the entire system. AnimatLab is a software tool that provides an approach to this problem through computer simulation. AnimatLab enables a computational model of an animal's body to be constructed from simple building blocks, situated in a virtual 3D world subject to the laws of physics, and controlled by the activity of a multicellular, multicompartment neural circuit. Sensor receptors on the body surface and inside the body respond to external and internal signals and then excite central neurons, while motor neurons activate Hill muscle models that span the joints and generate movement. AnimatLab provides a common neuromechanical simulation environment in which to construct and test models of any skeletal animal, vertebrate or invertebrate. The use of AnimatLab is demonstrated in a neuromechanical simulation of human arm flexion and the myotactic and contact-withdrawal reflexes. Copyright (c) 2010 Elsevier B.V. All rights reserved.

Lab-scale study on the application of In-Adit-Sulfate-Reducing System for AMD control.

PubMed

Ji, S W; Kim, S J

2008-12-30

In a study of the 29 operating passive systems for acid mine drainage (AMD) treatment, 19 systems showed various performance problems. Some systems showed very low efficiency even without visible leakage or overflow. Though systems show fairly good efficiency in metal removal (mainly iron) and pH control, sulfate removal rates were very low which indicates the possibility of very poor sulfate reductions by Sulfate Reducing Bacteria (SRB). As an alternative method, In-Adit-Sulfate-Reducing System (IASRS), the method of placing the SAPS inside the adit, to have temperature constant at about 15 degrees C, was suggested. Lab-scale model experiments of IASRS were carried out. The models 1 and 2 were run at 15 degrees C and 25 degrees C, respectively. The model 1 contained about a half of COD in the beginning of the operation than that of model 2. Metal removal ratios were higher than 90% in both systems. Both systems showed the sulfate removal ratios of 23% and 27%, respectively, which were still considerably low, even though higher than those of presently operating systems. However, since the synthetic AMD used was very low in pH (2.8) and very high in sulfate concentration, if some suggested modifications were applied to the standard design, it is presumed that the sulfate removal ratio would have increased.

Biological groundwater denitrification systems: Lab-scale trials aimed at nitrous oxide production and emission assessment.

PubMed

Capodici, Marco; Avona, Alessia; Laudicina, Vito Armando; Viviani, Gaspare

2018-07-15

Bio-trenches are a sustainable option for treating nitrate contamination in groundwater. However, a possible side effect of this technology is the production of nitrous oxide, a greenhouse gas that can be found both dissolved in the liquid effluent as well as emitted as off gas. The aim of this study was to analyze NO 3 - removal and N 2 O production in lab-scale column trials. The column contained olive nut as organic carbon media. The experimental study was divided into three phases (I, II and III) each characterized by different inlet NO 3 - concentrations (30, 50, 75mgNO 3 -NL -1 respectively). Sampling ports deployed along the length of the column allowed to observe the denitrification process as well as the formation and consumption of intermediate products, such as nitrite (NO 2 - ) and nitrous oxide (N 2 O). In particular, it was observed that N 2 O production represent only a small fraction of removed NO 3 - during Phase I and II, both for dissolved (0.007%) and emitted (0.003%) phase, and it was recorded a high denitrification efficiency, over 99%. Nevertheless, significantly higher values were recorded for Phase 3 concerning emitted phase (0.018%). This fact is due to increased inlet concentration which resulted in a carbon limitation and in a consequent decrease in denitrification efficiency (76%). Copyright © 2018 Elsevier B.V. All rights reserved.

Virtual Labs and Virtual Worlds

NASA Astrophysics Data System (ADS)

Boehler, Ted

2006-12-01

Virtual Labs and Virtual Worlds Coastline Community College has under development several virtual lab simulations and activities that range from biology, to language labs, to virtual discussion environments. Imagine a virtual world that students enter online, by logging onto their computer from home or anywhere they have web access. Upon entering this world they select a personalized identity represented by a digitized character (avatar) that can freely move about, interact with the environment, and communicate with other characters. In these virtual worlds, buildings, gathering places, conference rooms, labs, science rooms, and a variety of other “real world” elements are evident. When characters move about and encounter other people (players) they may freely communicate. They can examine things, manipulate objects, read signs, watch video clips, hear sounds, and jump to other locations. Goals of critical thinking, social interaction, peer collaboration, group support, and enhanced learning can be achieved in surprising new ways with this innovative approach to peer-to-peer communication in a virtual discussion world. In this presentation, short demos will be given of several online learning environments including a virtual biology lab, a marine science module, a Spanish lab, and a virtual discussion world. Coastline College has been a leader in the development of distance learning and media-based education for nearly 30 years and currently offers courses through PDA, Internet, DVD, CD-ROM, TV, and Videoconferencing technologies. Its distance learning program serves over 20,000 students every year. sponsor Jerry Meisner

Launching a virtual decision lab: development and field-testing of a web-based patient decision support research platform.

PubMed

Hoffman, Aubri S; Llewellyn-Thomas, Hilary A; Tosteson, Anna N A; O'Connor, Annette M; Volk, Robert J; Tomek, Ivan M; Andrews, Steven B; Bartels, Stephen J

2014-12-12

Over 100 trials show that patient decision aids effectively improve patients' information comprehension and values-based decision making. However, gaps remain in our understanding of several fundamental and applied questions, particularly related to the design of interactive, personalized decision aids. This paper describes an interdisciplinary development process for, and early field testing of, a web-based patient decision support research platform, or virtual decision lab, to address these questions. An interdisciplinary stakeholder panel designed the web-based research platform with three components: a) an introduction to shared decision making, b) a web-based patient decision aid, and c) interactive data collection items. Iterative focus groups provided feedback on paper drafts and online prototypes. A field test assessed a) feasibility for using the research platform, in terms of recruitment, usage, and acceptability; and b) feasibility of using the web-based decision aid component, compared to performance of a videobooklet decision aid in clinical care. This interdisciplinary, theory-based, patient-centered design approach produced a prototype for field-testing in six months. Participants (n = 126) reported that: the decision aid component was easy to use (98%), information was clear (90%), the length was appropriate (100%), it was appropriately detailed (90%), and it held their interest (97%). They spent a mean of 36 minutes using the decision aid and 100% preferred using their home/library computer. Participants scored a mean of 75% correct on the Decision Quality, Knowledge Subscale, and 74 out of 100 on the Preparation for Decision Making Scale. Completing the web-based decision aid reduced mean Decisional Conflict scores from 31.1 to 19.5 (p < 0.01). Combining decision science and health informatics approaches facilitated rapid development of a web-based patient decision support research platform that was feasible for use in research studies in

[Diagnostic test scale SI5: Assessment of sacroiliac joint dysfunction].

PubMed

Acevedo González, Juan C; Quintero Oliveros, Silvia

2015-01-01

Sacroiliac joint dysfunction is a known cause of low back pain. We think that a diagnostic score scale (SI5) may be performed to assess diagnostic utility of clinical signs of sacroiliac joint dysfunction. The primary aim of the present study was to conduct the pilot study of our new diagnostic score scale, the SI5, for sacroiliac joint syndrome. We reviewed the literature on clinical characteristics, diagnostic tests and imaging most commonly used in diagnosing sacroiliac joint dysfunction. Our group evaluated the diagnostic utility of these aspects and we used those considered most representative to develop the SI5 diagnostic scale. The SI5 scale was applied to 22 patients with low back pain; afterwards, the standard test for diagnosing this pathology (selective blockage of the SI joint) was also performed on these patients. The sensitivity and specificity for each sign were also assessed and the diagnostic scale called SI5 was then proposed, based on these data. The most sensitive clinical tests for diagnosing SI joint dysfunction were 2 patient-reported clinical characteristics, the Laguerre Test, sacroiliac rocking test and Yeomans test (greater than 80% sensitivity). The tests with greatest diagnostic specificity (>80%) were the Lewitt test, Piedallu test and Gillet test. The proposed SI5 test score scale showed sensitivity of 73% and specificity of 71%. Sacroiliac joint syndrome has been shown to produce low back pain frequently; however, the diagnostic value of examination tests for sacroiliac joint pain has been questioned by other authors. The pilot study on the SI5 diagnostic score scale showed good sensitivity and specificity. However, the process of statistical validation of the SI5 needs to be continued. Copyright © 2014 Sociedad Española de Neurocirugía. Published by Elsevier España. All rights reserved.

Propulsion Systems Lab

NASA Image and Video Library

2015-04-14

NASA Glenn’s Propulsion Systems Lab (PSL) is conducting research to characterize ice crystal clouds that can create a hazard to aircraft engines in certain conditions. With specialized equipment, scientists can create a simulated ice crystal cloud with the set of bars in the back spraying out a mist. The red area includes lasers, which measure the intensity of the cloud and a series of probes to measure everything from humidity to air pressure. The isokinetic probe (in gold) samples particles and the robotic arm (in orange) has a test tube on the end that catches ice particles for further measuring. NASA Glenn’s PSL is the only place in the world which can create these kind of ice crystal cloud conditions.

0.4 Percent Scale Space Launch System Wind Tunnel Test

NASA Image and Video Library

2011-11-15

0.4 Percent Scale Space Launch System Wind Tunnel Test 0.4 Percent Scale SLS model installed in the NASA Langley Research Center Unitary Plan Wind Tunnel Test Section 1 for aerodynamic force and movement testing.

7. View of interior, EPA Farm Lab Building 1506 milk ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. View of interior, EPA Farm Lab Building 15-06 milk room, facing west - Nevada Test Site, Environmental Protection Agency Farm, Laboratory Building, Area 15, Yucca Flat, 10-2 Road near Circle Road, Mercury, Nye County, NV

6. View of interior, EPA Farm Lab Building 1506 milking ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. View of interior, EPA Farm Lab Building 15-06 milking area, facing northwest - Nevada Test Site, Environmental Protection Agency Farm, Laboratory Building, Area 15, Yucca Flat, 10-2 Road near Circle Road, Mercury, Nye County, NV

Equating in Small-Scale Language Testing Programs

ERIC Educational Resources Information Center

LaFlair, Geoffrey T.; Isbell, Daniel; May, L. D. Nicolas; Gutierrez Arvizu, Maria Nelly; Jamieson, Joan

2017-01-01

Language programs need multiple test forms for secure administrations and effective placement decisions, but can they have confidence that scores on alternate test forms have the same meaning? In large-scale testing programs, various equating methods are available to ensure the comparability of forms. The choice of equating method is informed by…

GeneLab

NASA Technical Reports Server (NTRS)

Berrios, Daniel C.; Thompson, Terri G.

2015-01-01

NASA GeneLab is expected to capture and distribute omics data and experimental and process conditions most relevant to research community in their statistical and theoretical analysis of NASAs omics data.

Clay and Shale Permeability at Lab to Regional Scale

NASA Astrophysics Data System (ADS)

Neuzil, C.

2017-12-01

Because clays, shales, and other clay-rich media tend to be only poorly permeable, and are laterally extensive and voluminous, they play key roles in problems as diverse as groundwater supply, waste confinement, exploitation of conventional and unconventional oil and gas, and deformation and failure in the crust. Clay and shale permeability is a crucial but often highly uncertain analysis parameter; direct measurements are challenging, error-prone, and - perhaps most importantly - provide information only at quite small scales. Fortunately, there has been a dramatic increase in clay and shale permeability data from sources that include scientific ocean drilling, nuclear waste repository research, groundwater resource studies, liquid waste and CO2 sequestration, and oil and gas research. The effect of lithology as well as porosity on matrix permeability can now be examined and permeability - scale relations are becoming discernable. A significant number of large-scale permeability estimates have been obtained by inverse methods that essentially treat large-scale flow systems as natural experiments. They suggest surprisingly little scale-dependence in clay and shale permeabilities in subsiding basins and accretionary complexes. Stable continental settings present a different picture; as depths increase beyond 1 km, scale dependence mostly disappears even over the largest areas. At depths less than 1 km, secondary permeability is not always present over areas of 1 - 10 km2, but always evident for areas in excess of about 103 km2. Transmissive fractures have been observed in very low porosity (< 0.03) shales in these settings, but the cause of scale dependence in other cases is unclear; it may reflect time-dependent, or "dynamic" conditions, including irreversible and ongoing changes imposed on subsurface flow systems by human activities.

Inductance Scaling of a Helicoil Using ALEGRA

DTIC Science & Technology

2013-05-01

HOUSKAMP 3 US ARMY RESEARCH LAB RDRL WMP E P BARTKOWSKI D HORNBAKER P SWOBODA 1 US ARMY RESEARCH LAB RDRL WMP F N GNIAZDOWSKI 1 US ARMY RESEARCH LAB RDRL...HAILL 1 UNIVERSITY OF ALABAMA AT BIRMINGHAM D LITTLEFIELD 1 DEFENSE RESEARCH AGENCY B JAMES 2 ENIG ASSOCIATES, INC. E ENIG D BENTZ 42 ...January 2012 Inductance Scaling of a Helicoil Using ALEGRA Robert Doney U.S. Army Research Laboratory ATTN: RDRL-WMP- D Aberdeen Proving Ground, MD 21005

Field Testing of a Wet FGD Additive for Enhanced Mercury Control - Pilot-Scale Test Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gary M. Blythe

2006-03-01

This Topical Report summarizes progress on Cooperative Agreement DE-FC26-04NT42309, ''Field Testing of a Wet FGD Additive.'' The objective of the project is to demonstrate the use of a flue gas desulfurization (FGD) additive, Degussa Corporation's TMT-15, to prevent the reemissions of elemental mercury (Hg{sup 0}) in flue gas exiting wet FGD systems on coal-fired boilers. Furthermore, the project intends to demonstrate that the additive can be used to precipitate most of the mercury (Hg) removed in the wet FGD system as a fine TMT salt that can be separated from the FGD liquor and bulk solid byproducts for separate disposal.more » The project will conduct pilot and full-scale tests of the TMT-15 additive in wet FGD absorbers. The tests are intended to determine required additive dosage requirements to prevent Hg{sup 0} reemissions and to separate mercury from the normal FGD byproducts for three coal types: Texas lignite/Power River Basin (PRB) coal blend, high-sulfur Eastern bituminous coal, and low-sulfur Eastern bituminous coal. The project team consists of URS Group, Inc., EPRI, TXU Generation Company LP, Southern Company, and Degussa Corporation. TXU Generation has provided the Texas lignite/PRB co-fired test site for pilot FGD tests, Monticello Steam Electric Station Unit 3. Southern Company is providing the low-sulfur Eastern bituminous coal host site for wet scrubbing tests, as well as the pilot and full-scale jet bubbling reactor (JBR) FGD systems to be tested. A third utility, to be named later, will provide the high-sulfur Eastern bituminous coal full-scale FGD test site. Degussa Corporation is providing the TMT-15 additive and technical support to the test program. The project is being conducted in six tasks. Of the six project tasks, Task 1 involves project planning and Task 6 involves management and reporting. The other four tasks involve field testing on FGD systems, either at pilot or full scale. The four tasks include: Task 2 - Pilot Additive

Impact of non-ionic surfactant on the long-term development of lab-scale-activated sludge bacterial communities.

PubMed

Lozada, Mariana; Basile, Laura; Erijman, Leonardo

2007-01-01

The development of bacterial communities in replicate lab-scale-activated sludge reactors degrading a non-ionic surfactant was evaluated by statistical analysis of denaturing gradient gel electrophoresis (DGGE) fingerprints. Four sequential batch reactors were fed with synthetic sewage, two of which received, in addition, 0.01% of nonylphenol ethoxylates (NPE). The dynamic character of bacterial community structure was confirmed by the differences in species composition among replicate reactors. Measurement of similarities between reactors was obtained by pairwise similarity analysis using the Bray Curtis coefficient. The group of NPE-amended reactors exhibited the highest similarity values (Sjk=0.53+/-0.03), indicating that the bacterial community structure of NPE-amended reactors was better replicated than control reactors (Sjk=0.36+/-0.04). Replicate NPE-amended reactors taken at different times of operation clustered together, whereas analogous relations within the control reactor cluster were not observed. The DGGE pattern of isolates grown in conditioned media prepared with media taken at the end of the aeration cycle grouped separately from other conditioned and synthetic media regardless of the carbon source amendment, suggesting that NPE degradation residuals could have a role in the shaping of the community structure.

Awakening interest in the natural sciences - BASF's Kids' Labs.

PubMed

Lang, Cinthia

2012-01-01

At BASF's Ludwigshafen headquarters, kids and young adults in grades 1-13 can learn about chemistry in the Kids' Labs. Different programs exist for different levels of knowledge. In the two 'Hands-on Lab H(2)O & Co.' Kids' Labs, students from grades 1-6 explore the secrets of chemistry. BASF Kids' Labs have now been set up in over 30 countries. In Switzerland alone, almost 2,000 students have taken part in the 'Water Loves Chemistry' Kids' Lab since it was started in 2011. In Alsace, 600 students have participated to date. In the Teens' Lab 'Xplore Middle School', middle school students explore five different programs with the themes 'substance labyrinth', 'nutrition', 'coffee, caffeine & co.', 'cosmetics' and 'energy'. Biotechnological methods are the focus of the Teens' Lab 'Xplore Biotech' for students taking basic and advanced biology courses. In the 'Xplore High School' Teens' Lab, chemistry teachers present their own experimental lab instruction for students in basic and advanced chemistry courses. The Virtual Lab has been expanding the offerings of the BASF Kids' Labs since 2011. The online lab was developed by the company for the International Year Of Chemistry and gives kids and young adults the opportunity to do interactive experiments outside of the lab.

Three pedagogical approaches to introductory physics labs and their effects on student learning outcomes

NASA Astrophysics Data System (ADS)

Chambers, Timothy

This dissertation presents the results of an experiment that measured the learning outcomes associated with three different pedagogical approaches to introductory physics labs. These three pedagogical approaches presented students with the same apparatus and covered the same physics content, but used different lab manuals to guide students through distinct cognitive processes in conducting their laboratory investigations. We administered post-tests containing multiple-choice conceptual questions and free-response quantitative problems one week after students completed these laboratory investigations. In addition, we collected data from the laboratory practical exam taken by students at the end of the semester. Using these data sets, we compared the learning outcomes for the three curricula in three dimensions of ability: conceptual understanding, quantitative problem-solving skill, and laboratory skills. Our three pedagogical approaches are as follows. Guided labs lead students through their investigations via a combination of Socratic-style questioning and direct instruction, while students record their data and answers to written questions in the manual during the experiment. Traditional labs provide detailed written instructions, which students follow to complete the lab objectives. Open labs provide students with a set of apparatus and a question to be answered, and leave students to devise and execute an experiment to answer the question. In general, we find that students performing Guided labs perform better on some conceptual assessment items, and that students performing Open labs perform significantly better on experimental tasks. Combining a classical test theory analysis of post-test results with in-lab classroom observations allows us to identify individual components of the laboratory manuals and investigations that are likely to have influenced the observed differences in learning outcomes associated with the different pedagogical approaches. Due to

Using hot lab to increase pre-service physics teacher’s critical thinking skills related to the topic of RLC circuit

NASA Astrophysics Data System (ADS)

Malik, A.; Setiawan, A.; Suhandi, A.; Permanasari, A.; Samsudin, A.; Safitri, D.; Lisdiani, S. A. S.; Sapriadil, S.; Hermita, N.

2018-05-01

This research purposes to explore the used of Higher Order Thinking Laboratory (HOT-Lab) in enhancing the critical thinking skills of pre-service teachers related to the topic of Resistors, Inductors, Capacitor (RLC circuit). This study utilised a quasi-experiment method with Pretest-Posttest Control Group design. The sample of the study was 60 students that were divided into two groups covering in experiment and control group, consists of 30 students. The instrument for measuring critical thinking skills is essay test. Data has been analyzed using normalized gain average, effect size, and t-test. The results show that students’ critical thinking skills using the HOT Lab are higher than the verification lab. Using HOT-lab was implemented in the form of activity in the laboratory can improve high-order thinking skills. Hence, it was concluded that the use of HOT Lab had a greater impact on improving students’ critical thinking skills on RLC topic. Finally, HOT Lab can be used for other physics topics.

Optical development system lab alignment solutions for the ICESat-2 ATLAS instrument

NASA Astrophysics Data System (ADS)

Evans, T.

The ATLAS Instrument for the ICESat-2 mission at NASA's Goddard Space Flight Center requires an alignment test-bed to prove out new concepts. The Optical Development System (ODS) lab was created to test prototype models of individual instrument components to simulate how they will act as a system. The main ICESat-2 instrument is the Advanced Topographic Laser Altimeter System (ATLAS). It measures ice elevation by transmitting laser pulses, and collecting the reflection in a telescope. Because the round trip time is used to calculate distance, alignment between the outgoing transmitter beam and the incoming receiver beams are critical. An automated closed loop monitoring control system is currently being tested at the prototype level to prove out implementation for the final spacecraft. To achieve an error of less than 2 micro-radians, an active deformable mirror was used to correct the lab wave front from the collimated “ ground reflection” beam. The lab includes a focal plane assembly set up, a one meter diameter collimator optic, and a 0.8 meter flight spare telescope for alignment. ATLAS prototypes and engineering models of transmitter and receiver optics and sub-systems are brought in to develop and integrate systems as well as write procedures to be used in integration and testing. By having a fully integrated system with prototypes and engineering units, lessons can be learned before flight designs are finalized.

The Infant Version of the Laboratory Temperament Assessment Battery (Lab-TAB): Measurement Properties and Implications for Concepts of Temperament

PubMed Central

Planalp, Elizabeth M.; Van Hulle, Carol; Gagne, Jeffrey R.; Goldsmith, H. Hill

2017-01-01

We describe large-sample research using the Infant Laboratory Temperament Assessment Battery (Lab-TAB; Goldsmith and Rothbart, 1996) in 1,076 infants at 6 and 12 months of age. The Lab-TAB was designed to assess temperament dimensions through a series of episodes that mimic everyday situations. Our goal is to provide guidelines for scoring Lab-TAB episodes to derive temperament composites. We also present a set of analyses examining mean differences and stability of temperament in early infancy, gender differences in infant temperament, as well as a validation of Lab-TAB episodes and composites with parent reported Infant Behavior Questionnaire (IBQ; Rothbart, 1981) scales. In general, laboratory observed temperament was only modestly related to parent reported temperament. However, temperament measures were significantly stable across time and several gender differences that align with previous research emerged. In sum, the Lab-TAB usefully assesses individual differences in infant emotionality. PMID:28596748

Improving laboratory efficiencies to scale-up HIV viral load testing.

PubMed

Alemnji, George; Onyebujoh, Philip; Nkengasong, John N

2017-03-01

Viral load measurement is a key indicator that determines patients' response to treatment and risk for disease progression. Efforts are ongoing in different countries to scale-up access to viral load testing to meet the Joint United Nations Programme on HIV and AIDS target of achieving 90% viral suppression among HIV-infected patients receiving antiretroviral therapy. However, the impact of these initiatives may be challenged by increased inefficiencies along the viral load testing spectrum. This will translate to increased costs and ineffectiveness of scale-up approaches. This review describes different parameters that could be addressed across the viral load testing spectrum aimed at improving efficiencies and utilizing test results for patient management. Though progress is being made in some countries to scale-up viral load, many others still face numerous challenges that may affect scale-up efficiencies: weak demand creation, ineffective supply chain management systems; poor specimen referral systems; inadequate data and quality management systems; and weak laboratory-clinical interface leading to diminished uptake of test results. In scaling up access to viral load testing, there should be a renewed focus to address efficiencies across the entire spectrum, including factors related to access, uptake, and impact of test results.

Fabrication of Lab-on-Paper Using Porous Au-Paper Electrode: Application to Tumor Marker Electrochemical Immunoassays.

PubMed

Ge, Shenguang; Zhang, Yan; Yan, Mei; Huang, Jiadong; Yu, Jinghua

2017-01-01

A simple, low-cost, and sensitive electrochemical lab-on-paper assay is developed based on a novel gold nanoparticle modified porous paper working electrode for use in point-of-care testing (POCT). Electrochemical methods are introduced for lab-on-paper based on screen-printed paper electrodes. To further improve specificity, performance, and sensitivity for point-of-care testing, a novel porous Au-paper working electrode (Au-PWE) is designed for lab-on-paper using growth of an interconnected Au nanoparticle (NP) layer on the surface of cellulose fibers in order to enhance the conductivity of the paper sample zone and immobilize the primary antibodies (Ab1). With a sandwich-type immunoassay format, Pd-Au bimetallic nanoparticles possessing peroxidase-like activity are used as a matrix to immobilize secondary antibodies (Ab2) for rapid detection of targets. This lab-on-paper based immunodevice is applied to the diagnosis of a cancer biomarker in clinical serum samples.

Lab-on-fiber technology: a new vision for chemical and biological sensing.

PubMed

Ricciardi, Armando; Crescitelli, Alessio; Vaiano, Patrizio; Quero, Giuseppe; Consales, Marco; Pisco, Marco; Esposito, Emanuela; Cusano, Andrea

2015-12-21

The integration of microfluidics and photonic biosensors has allowed achievement of several laboratory functions in a single chip, leading to the development of photonic lab-on-a-chip technology. Although a lot of progress has been made to implement such sensors in small and easy-to-use systems, many applications such as point-of-care diagnostics and in vivo biosensing still require a sensor probe able to perform measurements at precise locations that are often hard to reach. The intrinsic property of optical fibers to conduct light to a remote location makes them an ideal platform to meet this demand. The motivation to combine the good performance of photonic biosensors on chips with the unique advantages of optical fibers has thus led to the development of the so-called lab-on-fiber technology. This emerging technology envisages the integration of functionalized materials on micro- and nano-scales (i.e. the labs) with optical fibers to realize miniaturized and advanced all-in-fiber probes, especially useful for (but not limited to) label-free chemical and biological applications. This review presents a broad overview of lab-on-fiber biosensors, with particular reference to lab-on-tip platforms, where the labs are integrated on the optical fiber facet. Light-matter interaction on the fiber tip is achieved through the integration of thin layers of nanoparticles or nanostructures supporting resonant modes, both plasmonic and photonic, highly sensitive to local modifications of the surrounding environment. According to the physical principle that is exploited, different configurations - such as localized plasmon resonance probes, surface enhanced Raman scattering probes and photonic probes - are classified, while various applications are presented in context throughout. For each device, the surface chemistry and the related functionalization protocols are reviewed. Moreover, the implementation strategies and fabrication processes, either based on bottom-up or top

Bone Marrow Test: MedlinePlus Lab Test Information

MedlinePlus

... this page: https://medlineplus.gov/labtests/bonemarrowtest.html Bone Marrow Test To use the sharing features on this page, please enable JavaScript. What Are Bone Marrow Tests? Bone marrow is a soft, spongy ...

Automated Lab-on-a-Chip Technology for Fish Embryo Toxicity Tests Performed under Continuous Microperfusion (μFET).

PubMed

Zhu, Feng; Wigh, Adriana; Friedrich, Timo; Devaux, Alain; Bony, Sylvie; Nugegoda, Dayanthi; Kaslin, Jan; Wlodkowic, Donald

2015-12-15

The fish embryo toxicity (FET) biotest has gained popularity as one of the alternative approaches to acute fish toxicity tests in chemical hazard and risk assessment. Despite the importance and common acceptance of FET, it is still performed in multiwell plates and requires laborious and time-consuming manual manipulation of specimens and solutions. This work describes the design and validation of a microfluidic Lab-on-a-Chip technology for automation of the zebrafish embryo toxicity test common in aquatic ecotoxicology. The innovative device supports rapid loading and immobilization of large numbers of zebrafish embryos suspended in a continuous microfluidic perfusion as a means of toxicant delivery. Furthermore, we also present development of a customized mechatronic automation interface that includes a high-resolution USB microscope, LED cold light illumination, and miniaturized 3D printed pumping manifolds that were integrated to enable time-resolved in situ analysis of developing fish embryos. To investigate the applicability of the microfluidic FET (μFET) in toxicity testing, copper sulfate, phenol, ethanol, caffeine, nicotine, and dimethyl sulfoxide were tested as model chemical stressors. Results obtained on a chip-based system were compared with static protocols performed in microtiter plates. This work provides evidence that FET analysis performed under microperfusion opens a brand new alternative for inexpensive automation in aquatic ecotoxicology.

Williams works with LOCAD-PTS in Destiny lab

NASA Image and Video Library

2007-04-01

ISS014-E-18822 (31 March 2007) --- Astronaut Sunita L. Williams, Expedition 14 flight engineer, works with the Lab-on-a-Chip Application Development-Portable Test System (LOCAD-PTS) experiment in the Destiny laboratory of the International Space Station. LOCAD-PTS is a handheld device for rapid detection of biological and chemical substances onboard the station.

Williams works with LOCAD-PTS in Destiny lab

NASA Image and Video Library

2007-04-01

ISS014-E-18818 (31 March 2007) --- Astronaut Sunita L. Williams, Expedition 14 flight engineer, works with the Lab-on-a-Chip Application Development-Portable Test System (LOCAD-PTS) experiment in the Destiny laboratory of the International Space Station. LOCAD-PTS is a handheld device for rapid detection of biological and chemical substances onboard the station.

Williams works with LOCAD-PTS in Destiny lab

NASA Image and Video Library

2007-04-01

ISS014-E-18811 (31 March 2007) --- Astronaut Sunita L. Williams, Expedition 14 flight engineer, works with the Lab-on-a-Chip Application Development-Portable Test System (LOCAD-PTS) experiment in the Destiny laboratory of the International Space Station. LOCAD-PTS is a handheld device for rapid detection of biological and chemical substances onboard the station.

Albumin Blood Test: MedlinePlus Lab Test Information

MedlinePlus

... Information → Albumin Blood Test URL of this page: https://medlineplus.gov/labtests/albuminbloodtest.html Albumin Blood Test ... 2017 Apr 26]; [about 3 screens]. Available from: https://www.liverfoundation.org/for-patients/about-the-liver/ ...

MPV Blood Test: MedlinePlus Lab Test Information

MedlinePlus

... https://medlineplus.gov/labtests/mpvbloodtest.html MPV Blood Test To use the sharing features on this page, please enable JavaScript. What is an MPV Blood Test? MPV stands for mean platelet volume. Platelets are ...

Flu (Influenza) Test: MedlinePlus Lab Test Information

MedlinePlus

... https://medlineplus.gov/labtests/fluinfluenzatest.html Flu (Influenza) Test To use the sharing features on this page, please enable JavaScript. What is a Flu (Influenza) Test? Influenza, known as the flu , is a respiratory ...

ALT Blood Test: MedlinePlus Lab Test Information

MedlinePlus

... https://medlineplus.gov/labtests/altbloodtest.html ALT Blood Test To use the sharing features on this page, please enable JavaScript. What is an ALT Blood Test? ALT, which stands for alanine transaminase, is an ...

Curricular Adaptations in Introductory Physics Labs

NASA Astrophysics Data System (ADS)

Dreyfus, Benjamin W.; Ewell, Mary; Moore, Kimberly

2017-01-01

When curricular materials are disseminated to new sites, there can be a tension between fidelity to the original intent of the developers and adaptation to local needs. In this case study we look at a lab activity that was initially developed for an introductory physics for the life sciences (IPLS) course at the University of Maryland, then implemented at George Mason University with significant adaptations. The goals of the two implementations were overlapping, but also differed in ways that are reflected in the two versions of the lab. We compare student lab report data from the two sites to examine the impacts of the adaptation on how students engaged with the lab.

Lab architecture

NASA Astrophysics Data System (ADS)

Crease, Robert P.

2008-04-01

There are few more dramatic illustrations of the vicissitudes of laboratory architecturethan the contrast between Building 20 at the Massachusetts Institute of Technology (MIT) and its replacement, the Ray and Maria Stata Center. Building 20 was built hurriedly in 1943 as temporary housing for MIT's famous Rad Lab, the site of wartime radar research, and it remained a productive laboratory space for over half a century. A decade ago it was demolished to make way for the Stata Center, an architecturally striking building designed by Frank Gehry to house MIT's computer science and artificial intelligence labs (above). But in 2004 - just two years after the Stata Center officially opened - the building was criticized for being unsuitable for research and became the subject of still ongoing lawsuits alleging design and construction failures.

Ensuring Positiveness of the Scaled Difference Chi-square Test Statistic.

PubMed

Satorra, Albert; Bentler, Peter M

2010-06-01

A scaled difference test statistic [Formula: see text] that can be computed from standard software of structural equation models (SEM) by hand calculations was proposed in Satorra and Bentler (2001). The statistic [Formula: see text] is asymptotically equivalent to the scaled difference test statistic T̄(d) introduced in Satorra (2000), which requires more involved computations beyond standard output of SEM software. The test statistic [Formula: see text] has been widely used in practice, but in some applications it is negative due to negativity of its associated scaling correction. Using the implicit function theorem, this note develops an improved scaling correction leading to a new scaled difference statistic T̄(d) that avoids negative chi-square values.

The U.S. Lab is moved toward the open floor in the O&C Building

NASA Technical Reports Server (NTRS)

2000-01-01

In the Operations and Checkout Building, the U.S. Lab moves overhead toward the open floor after being lifted out of the vacuum chamber where it was tested for leaks. The test was very successful. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research.

2. Oblique view of EPA Farm Lab Building 1506 (with ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Oblique view of EPA Farm Lab Building 15-06 (with slaughter addition at far left), facing southwest - Nevada Test Site, Environmental Protection Agency Farm, Laboratory Building, Area 15, Yucca Flat, 10-2 Road near Circle Road, Mercury, Nye County, NV

Results of Large-Scale Spacecraft Flammability Tests

NASA Technical Reports Server (NTRS)

Ferkul, Paul; Olson, Sandra; Urban, David L.; Ruff, Gary A.; Easton, John; T'ien, James S.; Liao, Ta-Ting T.; Fernandez-Pello, A. Carlos; Torero, Jose L.; Eigenbrand, Christian;

Lab-on-a-brane: nanofibrous polymer membranes to recreate organ-capillary interfaces

NASA Astrophysics Data System (ADS)

Budhwani, Karim I.; Thomas, Vinoy; Sethu, Palaniappan

2016-03-01

Drug discovery is a complex and time consuming process involving significant basic research and preclinical evaluation prior to testing in patients. Preclinical studies rely extensively on animal models which often fail in human trials. Biomimetic microphysiological systems (MPS) using human cells can be a promising alternative to animal models; where critical interactions between different organ systems are recreated to provide physiologically relevant in vitro human models. Central here are blood-vessel networks, the interface controlling transport of cellular and biomolecular components between the circulating fluid and underlying tissue. Here we present a novel lab-on-a-brane (or lab-on-a-membrane) nanofluidics MPS that combines the elegance of lab-on-a-chip with the more realistic morphology of 3D fibrous tissue-engineering constructs. Our blood-vessel lab-on-a-brane effectively simulates in vivo vessel-tissue interface for evaluating transendothelial transport in various pharmacokinetic and nanomedicine applications. Attributes of our platform include (a) nanoporous barrier interface enabling transmembrane molecular transport, (b) transformation of substrate into nanofibrous 3D tissue matrix, (c) invertible-sandwich architecture, and (d) simple co-culture mechanism for endothelial and smooth muscle layers to accurately mimic arterial anatomy. Structural, mechanical, and transport characterization using scanning electron microscopy, stress/strain analysis, infrared spectroscopy, immunofluorescence, and FITC-Dextran hydraulic permeability confirm viability of this in vitro system. Thus, our lab-on-a-brane provides an effective and efficient, yet considerably inexpensive, physiologically relevant alternative for pharmacokinetic evaluation; possibly reducing animals used in preclinical testing, costs from false starts, and time-to-market. Furthermore, it can be configured in multiple simultaneous arrays for personalized and precision medicine applications and for

Lab-scale investigation on remediation of diesel-contaminated aquifer using microwave energy.

PubMed

Falciglia, Pietro P; Maddalena, Riccardo; Mancuso, Giuseppe; Messina, Valeria; Vagliasindi, Federico G A

2016-02-01

Aquifer contamination with diesel fuel is a worldwide environmental problem, and related available remediation technologies may not be adequately efficient, especially for the simultaneous treatment of both solid and water phases. In this paper, a lab-scale 2.45 GHz microwave (MW) treatment of an artificially diesel-contaminated aquifer was applied to investigate the effects of operating power (160, 350 and 500 W) and time on temperature profiles and contaminant removal from both solid and water phases. Results suggest that in diesel-contaminated aquifer MW remediation, power significantly influences the final reachable temperature and, consequently, contaminant removal kinetics. A maximum temperature of about 120 °C was reached at 500 W. Observed temperature values depended on the simultaneous irradiation of both aquifer grains and groundwater. In this case, solid phase heating is limited by the maximum temperature that interstitial water can reach before evaporation. A minimal residual diesel concentration of about 100 mg kg(-1) or 100 mg L(-1) was achieved by applying a power of 500 W for a time of 60 min for the solid or water phase, respectively. Measured residual TPH fractions showed that MW heating resulted in preferential effects of the removal of different TPH molecular weight fractions and that the evaporation-stripping phenomena plays a major role in final contaminant removal processes. The power low kinetic equation shows an excellent fit (r(2) > 0.993) with the solid phase residual concentration observed for all the powers investigated. A maximum diesel removal of 88 or 80% was observed for the MW treatment of the solid or water phase, respectively, highlighting the possibility to successfully and simultaneously remediate both the aquifer phases. Consequently, MW, compared to other biological or chemical-physical treatments, appears to be a better choice for the fast remediation of diesel-contaminated aquifers. Copyright © 2015 Elsevier

Improved LCI profile of LAB based on latest technology advances

DOE Office of Scientific and Technical Information (OSTI.GOV)

Berna, J.L.; Renta, C.

1995-12-31

The first technology used to produce LAB was introduced in the early 60`s and since then a continuous optimization process has taken place on this highly competitive product on which additional cost effectiveness improvements became highly challenging. The latest technology introduced in the market (CEPSA {minus} UOP DETAL) based on a fixed bed alkylation process, has already been proved on a commercial scale. The simplicity of the new technology as compared to current ones, namely HF, has proven to be very effective in reducing substantially the impact due to several major components of the Life Cycle Inventory (LCI) in particularmore » the emissions of the overall operation. Additional improvements in other aspects like energy consumption are extremely difficult to achieve today as this parameter has already been highly optimized during the last two decades making in fact LAB a highly effective chemical in terms of energy requirements as well as on raw material consumption. The results of the first LCI of the new LAB technology indicate a reduction of CO process emissions to nearly 1/2 as compared to standard HF process as well as reduction in solid waste to 1/3 of the corresponding HF process. Important reductions have also been noticed on NOx emissions with the new technology.« less

SOUTH WING, MTR661. INTERIOR DETAIL INSIDE LAB ROOM 131. CAMERA ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

SOUTH WING, MTR-661. INTERIOR DETAIL INSIDE LAB ROOM 131. CAMERA FACING NORTHEAST. NOTE CONCRETE BLOCK WALLS. SAFETY SHOWER AND EYE WASHER AT REAR WALL. INL NEGATIVE NO. HD46-7-2. Mike Crane, Photographer, 2/2005. - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

Evolution of language: An empirical study at eBay Big Data Lab

PubMed Central

Bodoff, David; Dai, Julie

2017-01-01

The evolutionary theory of language predicts that a language will tend towards fewer synonyms for a given object. We subject this and related predictions to empirical tests, using data from the eBay Big Data Lab which let us access all records of the words used by eBay vendors in their item titles, and by consumers in their searches. We find support for the predictions of the evolutionary theory of language. In particular, the mapping from object to words sharpens over time on both sides of the market, i.e. among consumers and among vendors. In addition, the word mappings used on the two sides of the market become more similar over time. Our research contributes to the literature on language evolution by reporting results of a truly unique large-scale empirical study. PMID:29261686

Exploring the changing learning environment of the gross anatomy lab.

PubMed

Hopkins, Robin; Regehr, Glenn; Wilson, Timothy D

2011-07-01

The objective of this study was to assess the impact of virtual models and prosected specimens in the context of the gross anatomy lab. In 2009, student volunteers from an undergraduate anatomy class were randomly assigned to study groups in one of three learning conditions. All groups studied the muscles of mastication and completed identical learning objectives during a 45-minute lab. All groups were provided with two reference atlases. Groups were distinguished by the type of primary tools they were provided: gross prosections, three-dimensional stereoscopic computer model, or both resources. The facilitator kept observational field notes. A prepost multiple-choice knowledge test was administered to evaluate students' learning. No significant effect of the laboratory models was demonstrated between groups on the prepost assessment of knowledge. Recurring observations included students' tendency to revert to individual memorization prior to the posttest, rotation of models to match views in the provided atlas, and dissemination of groups into smaller working units. The use of virtual lab resources seemed to influence the social context and learning environment of the anatomy lab. As computer-based learning methods are implemented and studied, they must be evaluated beyond their impact on knowledge gain to consider the effect technology has on students' social development.

Planning a Computer Lab: Considerations To Ensure Success.

ERIC Educational Resources Information Center

IALL Journal of Language Learning Technologies, 1994

1994-01-01

Presents points to consider when organizing a computer laboratory. These include the lab's overall objectives and how best to meet them; what type of students will use the lab; where the lab will be located; and what software and hardware can best meet the lab's overall objectives, population, and location requirements. Other factors include time,…

Large-Scale Low-Boom Inlet Test Overview

NASA Technical Reports Server (NTRS)

Hirt, Stefanie

2011-01-01

This presentation provides a high level overview of the Large-Scale Low-Boom Inlet Test and was presented at the Fundamental Aeronautics 2011 Technical Conference. In October 2010 a low-boom supersonic inlet concept with flow control was tested in the 8'x6' supersonic wind tunnel at NASA Glenn Research Center (GRC). The primary objectives of the test were to evaluate the inlet stability and operability of a large-scale low-boom supersonic inlet concept by acquiring performance and flowfield validation data, as well as evaluate simple, passive, bleedless inlet boundary layer control options. During this effort two models were tested: a dual stream inlet intended to model potential flight hardware and a single stream design to study a zero-degree external cowl angle and to permit surface flow visualization of the vortex generator flow control on the internal centerbody surface. The tests were conducted by a team of researchers from NASA GRC, Gulfstream Aerospace Corporation, University of Illinois at Urbana-Champaign, and the University of Virginia

TQM in a Computer Lab.

ERIC Educational Resources Information Center

Swanson, Dewey A.; Phillips, Julie A.

At the Purdue University School of Technology (PST) at Columbus, Indiana, the Total Quality Management (TQM) philosophy was used in the computer laboratories to better meet student needs. A customer satisfaction survey was conducted to gather data on lab facilities, lab assistants, and hardware/software; other sections of the survey included…

Berkeley Lab - Materials Sciences Division

Science.gov Websites

Synthesis Condensed Matter and Materials Physics Scattering and Instrumentation Science Centers Center for Berkeley Lab Berkeley Lab A-Z Index Phone Book Jobs Search DOE Search MSD Go MSD - Materials Sciences Division About Organization Contact Research Core Programs Materials Discovery, Design and

1. Overview of EPA Farm Lab Building 1506, Sioux silo ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Overview of EPA Farm Lab Building 15-06, Sioux silo and slaughter addition (featuring poles from hay shed), facing east-northeast. - Nevada Test Site, Environmental Protection Agency Farm, Area 15, Yucca Flat, 10-2 Road near Circle Road, Mercury, Nye County, NV

5. View of interior, EPA Farm Lab Building 1506 slaughter ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. View of interior, EPA Farm Lab Building 15-06 slaughter addition (featuring cold slaughter area), facing north-northeast - Nevada Test Site, Environmental Protection Agency Farm, Laboratory Building, Area 15, Yucca Flat, 10-2 Road near Circle Road, Mercury, Nye County, NV

78 FR 60245 - Privacy Act Systems of Records; LabWare Laboratory Information Management System

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-01

... Services Laboratories (NVSL). Diagnostic testing provides official test results for animal imports, exports.... Diagnostic testing is also done in connection with suspected foreign animal disease investigations and... of Records; LabWare Laboratory Information Management System AGENCY: Animal and Plant Health...

Microbes in Mascara: Hypothesis-Driven Research in a Nonmajor Biology Lab †

PubMed Central

Burleson, Kathryn M.; Martinez-Vaz, Betsy M.

2011-01-01

In this laboratory exercise, students were taught concepts of microbiology and scientific process through an everyday activity — cosmetic use. The students’ goals for the lab were to develop a hypothesis regarding microbial contamination in cosmetics, learn techniques to culture and differentiate microorganisms from cosmetics, and propose best practices in cosmetics use based on their findings. Prior to the lab, students took a pretest to assess their knowledge of scientific hypotheses, microbiology, and cosmetic safety. In the first week, students were introduced to microbiological concepts and methodologies, and cosmetic terminology and safety. Students completed a hypothesis-writing exercise before formulating and testing their own hypotheses regarding cosmetic contamination. Students provided a cosmetic of their own and, in consultation with their lab group, chose one product for testing. Samples were serially diluted and plated on a variety of selective media. In the second week, students analyzed their plates to determine the presence and diversity of microbes and if their hypotheses were supported. Students completed a worksheet of their results and were given a posttest to assess their knowledge. Average test scores improved from 5.2 (pretest) to 7.8 (posttest), with p-values < 0.0001. Seventy-nine percent (79%) of students correctly identified hypotheses that were not falsifiable or lacked variables, and 89% of students improved their scores on questions concerning safe cosmetic use. Ninety-one percent (91%) of students demonstrated increased knowledge of microbial concepts and methods. Based on our results, this lab is an easy, yet effective, way to enhance knowledge of scientific concepts for nonmajors, while maintaining relevance to everyday life. PMID:23653761

Creating a lab to facilitate high school student engagement in authentic paleoclimate science practices

NASA Astrophysics Data System (ADS)

Maloney, A.; Walsh, E.

2012-12-01

A solid understanding of timescales is crucial for any climate change discussion. This hands-on lab was designed as part of a dual-credit climate change course in which high school students can receive college credit. Using homemade ice cores, students have the opportunity to participate in scientific practices associated with collecting, processing, and interpreting temperature and CO2 data. Exploring millennial-scale cycles in ice core data and extending the CO2 record to the present allows students to discover timescales from an investigators perspective. The Ice Core Lab has been piloted in two high school classrooms and student engagement, and epistemological and conceptual understanding was evaluated using quantitative pre and post assessment surveys. The process of creating this lab involved a partnership between an education assessment professional, high school teachers, and University of Washington professors and graduate students in Oceanography, Earth and Space Sciences, Atmospheric Sciences and the Learning Sciences as part of the NASA Global Climate Change University of Washington in the High School program. This interdisciplinary collaboration led to the inception of the lab and was necessary to ensure that the lesson plan was pedagogically appropriate and scientifically accurate. The lab fits into a unit about natural variability and is paired with additional hands-on activities created by other graduate students that explore short-timescale temperature variations, Milankovitch cycles, isotopes, and other proxies. While the Ice Core Lab is intended to follow units that review the scientific process, global energy budget, and transport, it can be modified to fit any teaching platform.

EPICS Channel Access Server for LabVIEW

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhukov, Alexander P.

It can be challenging to interface National Instruments LabVIEW (http://www.ni.com/labview/) with EPICS (http://www.aps.anl.gov/epics/). Such interface is required when an instrument control program was developed in LabVIEW but it also has to be part of global control system. This is frequently useful in big accelerator facilities. The Channel Access Server is written in LabVIEW, so it works on any hardware/software platform where LabVIEW is available. It provides full server functionality, so any EPICS client can communicate with it.

Mechanical Stability of Fractured Rift Basin Mudstones: from lab to basin scale

NASA Astrophysics Data System (ADS)

Zakharova, N. V.; Goldberg, D.; Collins, D.; Swager, L.; Payne, W. G.

2016-12-01

Understanding petrophysical and mechanical properties of caprock mudstones is essential for ensuring good containment and mechanical formation stability at potential CO2 storage sites. Natural heterogeneity and presence of fractures, however, create challenges for accurate prediction of mudstone behavior under injection conditions and at reservoir scale. In this study, we present a multi-scale geomechanical analysis for Mesozoic mudstones from the Newark Rift basin, integrating petropyshical core and borehole data, in situ stress measurements, and caprock stability modeling. The project funded by the U.S. Department of Energy's National Energy Technology Laboratory (NETL) focuses on the Newark basin as a representative locality for a series of the Mesozoic rift basins in eastern North America considered as potential CO2 storage sites. An extensive core characterization program, which included laboratory CT scans, XRD, SEM, MICP, porosity, permeability, acoustic velocity measurements, and geomechanical testing under a range of confining pressures, revealed large variability and heterogeneity in both petrophysical and mechanical properties. Estimates of unconfined compressive strength for these predominantly lacustrine mudstones range from 5,000 to 50,000 psi, with only a weak correlation to clay content. Thinly bedded intervals exhibit up to 30% strength anisotropy. Mineralized fractures, abundant in most formations, are characterized by compressive strength as low as 10% of matrix strength. Upscaling these observations from core to reservoir scale is challenging. No simple one-to-one correlation between mechanical and petrophyscial properties exists, and therefore, we develop multivariate empirical relationships among these properties. A large suite of geophysical logs, including new measurements of the in situ stress field, is used to extrapolate these relationships to a basin-scale geomechanical model and predict mudstone behavior under injection conditions.

Future{at}Labs.Prosperity Game{trademark}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Beck, D.F.; Boyack, K.W.; Berman, M.

Prosperity Games{trademark} are an outgrowth and adaptation of move/countermove and seminar War Games, Prosperity Games{trademark} are simulations that explore complex issues in a variety of areas including economics, politics, sociology, environment, education, and research. These issues can be examined from a variety of perspectives ranging from global, macroeconomic and geopolitical viewpoint down to the details of customer/supplier/market interactions specific industries. All Prosperity Games{trademark} are unique in that both the game format and the player contributions vary from game to game. This report documents the Future{at}Labs.Prosperity Game{trademark} conducted under the sponsorship of the Industry Advisory Boards of the national labs, themore » national labs, Lockheed Martin Corporation, and the University of California. Players were drawn from all stakeholders involved including government, industry, labs, and academia. The primary objectives of this game were to: (1) explore ways to optimize the role of the multidisciplinary labs in serving national missions and needs; (2) explore ways to increase collaboration and partnerships among government, laboratories, universities, and industry; and (3) create a network of partnership champions to promote findings and policy options. The deliberations and recommendations of these players provided valuable insights as to the views of this diverse group of decision makers concerning the future of the labs.« less

Design of inquiry-oriented science labs: impacts on students' attitudes

NASA Astrophysics Data System (ADS)

Baseya, J. M.; Francis, C. D.

2011-11-01

Background: Changes in lab style can lead to differences in learning. Two inquiry-oriented lab styles are guided inquiry (GI) and problem-based (PB). Students' attitudes towards lab are important to consider when choosing between GI and PB styles during curriculum design. Purpose: We examined the degree to which lab experiences are explained by a GI or a PB lab style vs. students' attitudes towards specific aspects of the experience, reflected by perceived excitement (exc), difficulty (dif), time efficiency (eff) and association between lab and lecture material (help). Sample: Approximately 1000 students attending first-semester, college biology lab for science majors at the University of Colorado at Boulder, USA, participated in the study. Design and method: In 2007, two labs were run as GI and one as PB. Formats were switched in 2008. Attitudes were assessed with a post-semester survey. Results: Only the four attitude variables (not lab style) had a strong relationship with overall lab rating which was most strongly related to exc, followed by dif and help/eff. Dif and eff had the greatest influence on attitudes for or against GI vs. PB labs, and help and exc had little influence on a GI vs. a PB lab. Also, when dif was low, students' attitudes were not significantly different between PB and GI labs, but when dif was high, students' significantly rated GI labs higher than PB labs. Conclusions: Students' attitudes towards lab are more dependent on specific aspects of the experience than on lab style. Changes in GI vs. PB lab styles primarily influence dif and eff rather than exc and help. Dif may be an important factor to consider when implementing a lab in the PB vs. the GI format. It might be good to go with a GI when dif is high and a PB when dif is low.

Indirect scaling methods for testing quantitative emotion theories.

PubMed

Junge, Martin; Reisenzein, Rainer

2013-01-01

Two studies investigated the utility of indirect scaling methods, based on graded pair comparisons, for the testing of quantitative emotion theories. In Study 1, we measured the intensity of relief and disappointment caused by lottery outcomes, and in Study 2, the intensity of disgust evoked by pictures, using both direct intensity ratings and graded pair comparisons. The stimuli were systematically constructed to reflect variables expected to influence the intensity of the emotions according to theoretical models of relief/disappointment and disgust, respectively. Two probabilistic scaling methods were used to estimate scale values from the pair comparison judgements: Additive functional measurement (AFM) and maximum likelihood difference scaling (MLDS). The emotion models were fitted to the direct and indirect intensity measurements using nonlinear regression (Study 1) and analysis of variance (Study 2). Both studies found substantially improved fits of the emotion models for the indirectly determined emotion intensities, with their advantage being evident particularly at the level of individual participants. The results suggest that indirect scaling methods yield more precise measurements of emotion intensity than rating scales and thereby provide stronger tests of emotion theories in general and quantitative emotion theories in particular.

Science Lab: A Peer Approach.

ERIC Educational Resources Information Center

Ronca, Courtney C.

The two goals of this program were to increase the number of classroom teachers using the lab and to increase the amount of time that the science lab was used. The solution strategy chosen was a combination of peer tutoring, orientation presentations, small group discovery experiments and activities, and individual science experiment stations. The…

Irmo High School's Language Arts Lab: A Golden Opportunity.

ERIC Educational Resources Information Center

Ingle, Judith K.

Since 1984, the Language Arts Lab at Irmo High School (Columbia, South Carolina) has provided: (1) remediation in reading and writing to students with low standardized test scores; and (2) assistance to other students in the areas of study skills, college entrance exam preparation, term papers, reading and reading assignments, grammar, and…

Analyzing the dynamic response of rotating blades in small-scale wind turbines

NASA Astrophysics Data System (ADS)

Hsiung, Wan-Ying; Huang, Yu-Ting; Loh, Chin-Hsiung; Loh, Kenneth J.; Kamisky, Robert J.; Nip, Danny; van Dam, Cornelis

2014-03-01

The objective of this study was to validate modal analysis, system identification and damage detection of small-scale rotating wind turbine blades in the laboratory and in the field. Here, wind turbine blades were instrumented with accelerometers and strain gages, and data acquisition was achieved using a prototype wireless sensing system. In the first portion of this study conducted in the laboratory, sensors were installed onto metallic structural elements that were fabricated to be representative of an actual wind blade. In order to control the excitation (rotation of the wind blade), a motor was used to spin the blades at controlled angular velocities. The wind turbine was installed on a shaking table for testing under rotation of turbine blades. Data measured by the sensors were recorded while the blade was operated at different speeds. On the other hand, the second part of this study utilized a small-scale wind turbine system mounted on the rooftop of a building. The main difference, as compared to the lab tests, was that the field tests relied on actual wind excitations (as opposed to a controlled motor). The raw data from both tests were analyzed using signal processing and system identification techniques for deriving the model response of the blades. The multivariate singular spectrum analysis (MSSA) and covariance-driven stochastic subspace identification method (SSI-COV) were used to identify the dynamic characteristics of the system. Damage of one turbine blade (loose bolts connection) in the lab test was also conducted. The extracted modal properties for both undamaged and damage cases under different ambient or forced excitations (earthquake loading) were compared. These tests confirmed that dynamic characterization of rotating wind turbines was feasible, and the results will guide future monitoring studies planned for larger-scale systems.

3. View of EPA Farm Lab Building 1506 (with sliding ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. View of EPA Farm Lab Building 15-06 (with sliding doors open to slaughter addition) and Sioux silo, facing north-northwest - Nevada Test Site, Environmental Protection Agency Farm, Laboratory Building, Area 15, Yucca Flat, 10-2 Road near Circle Road, Mercury, Nye County, NV

Assessment of Student Learning in Modern Experiments in the Introductory Calculus-Based Physics Labs

NASA Astrophysics Data System (ADS)

Woodahl, Brian; Ross, John; Lang, Sarah; Scott, Derek; Williams, Jeremy

2010-10-01

With the advent of newer microelectronic sensors it's now possible to modernize introductory physics labs with the latest technology and this may allow for enhanced student participation/learning in the experiments. For example, force plate sensors can digitize and record the force on an object, later it can be analyzed in detail (i.e, impulse from force vs. time). Small 3-axis accelerometers can record 3-dim, time-dependent acceleration of objects undergoing complex motions. These devices are small, fairly easy to use, and importantly, are likely to enhance student learning by ``personalizing'' data collection, i.e. making the student an active part of the measurement process and no longer a passive observer. To assess whether these new high-tech labs enhance student learning, we have implemented pre- and post- test sessions to measure the effectiveness of student learning. Four of our calculus-based lab sections were used: Two sections the control group, using the previous ``old technology'' labs, the other two, the experimental group, using the new ``modern technology'' labs. Initial returns of assessment data offer some surprising insight.

Subsurface multidisciplinary research results at ICTJA-CSIC downhole lab and test site

NASA Astrophysics Data System (ADS)

Jurado, Maria Jose; Crespo, Jose; Salvany, Josep Maria; Teixidó, Teresa

2017-04-01

Two scientific boreholes, Almera-1 and Almera-2 were drilled in the Barcelona University campus area in 2011. The main purpose for this drilling was to create a new geophysical logging and downhole monitoring research facility and infrastructure. We present results obtained in the frame of multidisciplinary studies and experiments carried out since 2011 at the ICTJA "Borehole Geophysical Logging Lab - Scientific Boreholes Almera" downhole lab facilities. First results obtained from the scientific drilling, coring and logging allowed us to characterize the urban subsurface geology and hydrology adjacent to the Institute of Earth Sciences Jaume Almera (ICTJA-CSIC) in Barcelona. The subsurface geology and structural picture has been completed with recent geophysical studies and monitoring results. The upper section of Almera-1 214m deep hole was cased with PVC after drilling and after the logging operations. An open hole interval was left from 112m to TD (Paleozoic section). Almera-2 drilling reached 46m and was cased also with PVC to 44m. Since completion of the drilling in 2011, both Almera-1 and Almera-2 have been extensively used for research purposes, tests, training, hydrological and geophysical monitoring. A complete set of geophysical logging measurements and borehole oriented images were acquired in open hole mode of the entire Almera-1 section. Open hole measurements included acoustic and optical imaging, spectral natural gamma ray, full wave acoustic logging, magnetic susceptibility, hydrochemical-temperature logs and fluid sampling. Through casing (PVC casing) measurements included spectral gamma ray logging, full wave sonic and acoustic televiewer. A Quaternary to Paleozoic section was characterized based on the geophysical logging and borehole images interpretation and also on the complete set of (wireline) cores of the entire section. Sample availability was intended for geological macro and micro-facies detailed characterization, mineralogical and

How Reliable Is Laboratory Testing?

MedlinePlus

... laboratory testing. (See Who's Who in the Lab .) Post-Analytic Activities After the test is completed, the result must be delivered in ... View Sources NOTE: This article is based on research that ... of the Lab Tests Online Editorial Review Board . This article is periodically ...

Calcium in Urine Test: MedlinePlus Lab Test Information

MedlinePlus

... medlineplus.gov/labtests/calciuminurinetest.html Calcium in Urine Test To use the sharing features on this page, ... enable JavaScript. What is a Calcium in Urine Test? A calcium in urine test measures the amount ...

Lipoprotein (a) Blood Test: MedlinePlus Lab Test Information

MedlinePlus

... medlineplus.gov/labtests/lipoproteinabloodtest.html Lipoprotein (a) Blood Test To use the sharing features on this page, ... enable JavaScript. What is a Lipoprotein (a) Blood Test? A lipoprotein (a) test measures the level of ...

ANA (Antinuclear Antibody) Test: MedlinePlus Lab Test Information

MedlinePlus

... medlineplus.gov/labtests/anaantinuclearantibodytest.html ANA (Antinuclear Antibody) Test To use the sharing features on this page, ... enable JavaScript. What is an ANA (Antinuclear Antibody) Test? An ANA test looks for antinuclear antibodies in ...

Anion Gap Blood Test: MedlinePlus Lab Test Information

MedlinePlus

... medlineplus.gov/labtests/aniongapbloodtest.html Anion Gap Blood Test To use the sharing features on this page, ... enable JavaScript. What is an Anion Gap Blood Test? An anion gap blood test is a way ...

Control and Non-Payload Communications (CNPC) Prototype Radio - Generation 2 Security Architecture Lab Test Report

NASA Technical Reports Server (NTRS)

Iannicca, Dennis C.; McKim, James H.; Stewart, David H.; Thadhani, Suresh K.; Young, Daniel P.

2015-01-01

NASA Glenn Research Center, in cooperation with Rockwell Collins, is working to develop a prototype Control and Non-Payload Communications (CNPC) radio platform as part of NASA Integrated Systems Research Program's (ISRP) Unmanned Aircraft Systems (UAS) Integration in the National Airspace System (NAS) project. A primary focus of the project is to work with the FAA and industry standards bodies to build and demonstrate a safe, secure, and efficient CNPC architecture that can be used by industry to evaluate the feasibility of deploying a system using these technologies in an operational capacity. GRC has been working in conjunction with these groups to assess threats, identify security requirements, and to develop a system of standards-based security controls that can be applied to the current GRC prototype CNPC architecture as a demonstration platform. The security controls were integrated into a lab test bed mock-up of the Mobile IPv6 architecture currently being used for NASA flight testing, and a series of network tests were conducted to evaluate the security overhead of the controls compared to the baseline CNPC link without any security. The aim of testing was to evaluate the performance impact of the additional security control overhead when added to the Mobile IPv6 architecture in various modes of operation. The statistics collected included packet captures at points along the path to gauge packet size as the sample data traversed the CNPC network, round trip latency, jitter, and throughput. The effort involved a series of tests of the baseline link, a link with Robust Header Compression (ROHC) and without security controls, a link with security controls and without ROHC, and finally a link with both ROHC and security controls enabled. The effort demonstrated that ROHC is both desirable and necessary to offset the additional expected overhead of applying security controls to the CNPC link.

LANGUAGE LABS--AN UPDATED REPORT.

ERIC Educational Resources Information Center

1963

REPORTS FROM SEVERAL SCHOOL DISTRICTS ON THE USE OF AND PLANNING OF LANGUAGE LABORATORIES ARE PRESENTED. LABORATORIES SHOULD BE ARRANGED FOR FLEXIBLE USE. THE AVERAGE HIGH SCHOOL STUDENT CAN USE A LAB PROFITABLY FOR 20 TO 25 MINUTES. THERE ARE THREE DIFFERENT TYPES OF LANGUAGE LABORATORIES THAT ARE DESCRIBED. THE SATELLITE LAB IS DIVIDED BY A…

Academic Pipeline and Futures Lab

DTIC Science & Technology

2016-02-01

AFRL-RY-WP-TR-2015-0186 ACADEMIC PIPELINE AND FUTURES LAB Brian D. Rigling Wright State University FEBRUARY 2016...DD-MM-YY) 2. REPORT TYPE 3. DATES COVERED (From - To) February 2016 Final 12 June 2009 – 30 September 2015 4. TITLE AND SUBTITLE ACADEMIC ...6 3 WSU ACADEMIC PIPELINE AND LAYERED SENSING FUTURES LAB (prepared by K

NASA Glenn Propulsion Systems Lab (PSL) Icing Facility Update

NASA Technical Reports Server (NTRS)

Thomas, Queito P.

2015-01-01

The NASA Glenn Research Center Propulsion Systems Lab (PSL) was recently upgraded to perform engine inlet ice crystal testing in an altitude environment. The system installed 10 spray bars in the inlet plenum for ice crystal generation using 222 spray nozzles. As an altitude test chamber, PSL is capable of simulation of in-flight icing events in a ground test facility. The system was designed to operate at altitudes from 4,000 ft. to 40,000 ft. at Mach numbers up to 0.8M and inlet total temperatures from -60F to +15F.

Wellbore Completion Systems Containment Breach Solution Experiments at a Large Scale Underground Research Laboratory : Sealant placement & scale-up from Lab to Field

NASA Astrophysics Data System (ADS)

Goodman, H.

2017-12-01

This investigation seeks to develop sealant technology that can restore containment to completed wells that suffer CO2 gas leakages currently untreatable using conventional technologies. Experimentation is performed at the Mont Terri Underground Research Laboratory (MT-URL) located in NW Switzerland. The laboratory affords investigators an intermediate-scale test site that bridges the gap between the laboratory bench and full field-scale conditions. Project focus is the development of CO2 leakage remediation capability using sealant technology. The experimental concept includes design and installation of a field scale completion package designed to mimic well systems heating-cooling conditions that may result in the development of micro-annuli detachments between the casing-cement-formation boundaries (Figure 1). Of particular interest is to test novel sealants that can be injected in to relatively narrow micro-annuli flow-paths of less than 120 microns aperture. Per a special report on CO2 storage submitted to the IPCC[1], active injection wells, along with inactive wells that have been abandoned, are identified as one of the most probable sources of leakage pathways for CO2 escape to the surface. Origins of pressure leakage common to injection well and completions architecture often occur due to tensile cracking from temperature cycles, micro-annulus by casing contraction (differential casing to cement sheath movement) and cement sheath channel development. This discussion summarizes the experiment capability and sealant testing results. The experiment concludes with overcoring of the entire mock-completion test site to assess sealant performance in 2018. [1] IPCC Special Report on Carbon Dioxide Capture and Storage (September 2005), section 5.7.2 Processes and pathways for release of CO2 from geological storage sites, page 244

Towards a Manifesto for Living Lab Co-creation

NASA Astrophysics Data System (ADS)

Følstad, Asbjørn; Brandtzæg, Petter Bae; Gulliksen, Jan; Börjeson, Mikael; Näkki, Pirjo

There is a growing interest in Living Labs for innovation and development in the field of information and communication technology. In particular there seem to be a tendency that current Living Labs aim to involve users for co-creative purposes. However, the current literature on Living Lab co-creation is severely limited. Therefore an Interact workshop is arranged as a first step towards a manifesto for Living Lab co-creation.

A Remote Lab for Experiments with a Team of Mobile Robots

PubMed Central

Casini, Marco; Garulli, Andrea; Giannitrapani, Antonio; Vicino, Antonio

2014-01-01

In this paper, a remote lab for experimenting with a team of mobile robots is presented. Robots are built with the LEGO Mindstorms technology and user-defined control laws can be directly coded in the Matlab programming language and validated on the real system. The lab is versatile enough to be used for both teaching and research purposes. Students can easily go through a number of predefined mobile robotics experiences without having to worry about robot hardware or low-level programming languages. More advanced experiments can also be carried out by uploading custom controllers. The capability to have full control of the vehicles, together with the possibility to define arbitrarily complex environments through the definition of virtual obstacles, makes the proposed facility well suited to quickly test and compare different control laws in a real-world scenario. Moreover, the user can simulate the presence of different types of exteroceptive sensors on board of the robots or a specific communication architecture among the agents, so that decentralized control strategies and motion coordination algorithms can be easily implemented and tested. A number of possible applications and real experiments are presented in order to illustrate the main features of the proposed mobile robotics remote lab. PMID:25192316

A remote lab for experiments with a team of mobile robots.

PubMed

Casini, Marco; Garulli, Andrea; Giannitrapani, Antonio; Vicino, Antonio

2014-09-04

In this paper, a remote lab for experimenting with a team of mobile robots is presented. Robots are built with the LEGO Mindstorms technology and user-defined control laws can be directly coded in the Matlab programming language and validated on the real system. The lab is versatile enough to be used for both teaching and research purposes. Students can easily go through a number of predefined mobile robotics experiences without having to worry about robot hardware or low-level programming languages. More advanced experiments can also be carried out by uploading custom controllers. The capability to have full control of the vehicles, together with the possibility to define arbitrarily complex environments through the definition of virtual obstacles, makes the proposed facility well suited to quickly test and compare different control laws in a real-world scenario. Moreover, the user can simulate the presence of different types of exteroceptive sensors on board of the robots or a specific communication architecture among the agents, so that decentralized control strategies and motion coordination algorithms can be easily implemented and tested. A number of possible applications and real experiments are presented in order to illustrate the main features of the proposed mobile robotics remote lab.

Delta-ALA urine test

MedlinePlus

... hours. Normal value ranges may vary slightly from one lab to another. Some labs use different measurements or test different samples. Talk to your provider about the meaning of your specific test results. What Abnormal Results Mean An increased level of urinary delta-ALA may ...

Nitrification denitrification enhanced biological phosphorous removal (NDEBPR) occurs in a lab-scale alternating hypoxic/oxic membrane bioreactor.

PubMed

Sibag, Mark; Kim, Han-Seung

2012-01-01

Strict anaerobic or anoxic maintenance of the system and process susceptibility to low organic loading are major concerns in nitrification denitrification enhanced biological phosphorous removal (NDEBPR). The study has initiated NDEBPR in a lab-scale alternating hypoxic/oxic membrane bioreactor by developing an enhanced mixed microbial culture capable of removing 97±2% COD, 99±0.84% NH(3)-N, 90±3% TN, and 96±1% TP-PO(4)(3-) with 20-day SRT. The viable cells ranging from 1.6×10(8) to 2.0×10(8)cells/ml estimated from the total bacterial genomic DNA (6.43-7.83 μg DNA/ml) represented only 5% of the MLVSS indicating low microbial biomass concentration. Reducing the organic load from 1250 to 750 mg COD/ml as glucose did not deteriorate the effluent quality (3.77±1.0 mg N-TN/l; 0.08±0.24 mg NH(3)-N/l; and 0.32±0.10 mg PO(4)(3-)-P/l). These observations are characteristics of activated sludge that harbors denitrifying polyphosphate accumulating organisms (DPAOs). The results showed that NDEBPR can be achieved under alternating hypoxic/oxic conditions. Copyright © 2011 Elsevier Ltd. All rights reserved.

Lab-on-a-Chip Based Protein Crystallization

NASA Technical Reports Server (NTRS)

vanderWoerd, Mark J.; Brasseur, Michael M.; Spearing, Scott F.; Whitaker, Ann F. (Technical Monitor)

2001-01-01

We are developing a novel technique with which we will grow protein crystals in very small volumes, utilizing chip-based, microfluidic ("LabChip") technology. This development, which is a collaborative effort between NASA's Marshall Space Flight Center and Caliper Technologies Corporation, promises a breakthrough in the field of protein crystal growth. Our initial results obtained from two model proteins, Lysozyme and Thaumatin, show that it is feasible to dispense and adequately mix protein and precipitant solutions on a nano-liter scale. The mixtures have shown crystal growth in volumes in the range of 10 nanoliters to 5 microliters. In addition, large diffraction quality crystals were obtained by this method. X-ray data from these crystals were shown to be of excellent quality. Our future efforts will include the further development of protein crystal growth with LabChip(trademark) technology for more complex systems. We will initially address the batch growth method, followed by the vapor diffusion method and the liquid-liquid diffusion method. The culmination of these chip developments is to lead to an on orbit protein crystallization facility on the International Space Station. Structural biologists will be invited to utilize the on orbit Iterative Biological Crystallization facility to grow high quality macromolecular crystals in microgravity.

A Study of Cognitive Load for Enhancing Student’s Quantitative Literacy in Inquiry Lab Learning

NASA Astrophysics Data System (ADS)

Nuraeni, E.; Rahman, T.; Alifiani, D. P.; Khoerunnisa, R. S.

2017-09-01

Students often find it difficult to appreciate the relevance of the role of quantitative analysis and concept attainment in the science class. This study measured student cognitive load during the inquiry lab of the respiratory system to improve quantitative literacy. Participants in this study were 40 11th graders from senior high school in Indonesia. After students learned, their feelings about the degree of mental effort that it took to complete the learning tasks were measured by 28 self-report on a 4-point Likert scale. The Task Complexity Worksheet were used to asses processing quantitative information and paper based test were applied to assess participants’ concept achievements. The results showed that inquiry instructional induced a relatively low mental effort, high processing information and high concept achievments.

4. Oblique view of EPA Farm Lab Building 1506 (with ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Oblique view of EPA Farm Lab Building 15-06 (with sliding door open to milking area), Sioux silo and slaughter addition, facing northeast - Nevada Test Site, Environmental Protection Agency Farm, Laboratory Building, Area 15, Yucca Flat, 10-2 Road near Circle Road, Mercury, Nye County, NV

WETS - Azura Half Scale Testing MOIS Documentation

DOE Data Explorer

Nelson, Eric

2015-05-30

This submission includes documentation on the Modular Ocean Instrumentation System (MOIS) installation on the Azura 1/2 scale wave energy converter at the Marine Station Kaneohe Bay (MCBH). Data from the deployment will be uploaded over the course of the test. The instrumentation and data come from the NREL team participating in this testing.

Large-scale carbon fiber tests

NASA Technical Reports Server (NTRS)

Pride, R. A.

1980-01-01

A realistic release of carbon fibers was established by burning a minimum of 45 kg of carbon fiber composite aircraft structural components in each of five large scale, outdoor aviation jet fuel fire tests. This release was quantified by several independent assessments with various instruments developed specifically for these tests. The most likely values for the mass of single carbon fibers released ranged from 0.2 percent of the initial mass of carbon fiber for the source tests (zero wind velocity) to a maximum of 0.6 percent of the initial carbon fiber mass for dissemination tests (5 to 6 m/s wind velocity). Mean fiber lengths for fibers greater than 1 mm in length ranged from 2.5 to 3.5 mm. Mean diameters ranged from 3.6 to 5.3 micrometers which was indicative of significant oxidation. Footprints of downwind dissemination of the fire released fibers were measured to 19.1 km from the fire.

Extreme Environments Test Capabilities at NASA GRC for Parker Hannifin Visit

NASA Technical Reports Server (NTRS)

Arnett, Lori

2016-01-01

The presentation includes general description on the following test facilities: Fuel Cell Testing Lab, Structural Dynamics Lab, Thermal Vacuum Test Facilities - including a description of the proposed Kinetic High Altitude Simulator concept, EMI Test Lab, and the Creek Road Cryogenic Complex - specifically the Small Multi-purpose Research Facility (SMiRF) and the Cryogenics Components Lab 7 (CCL-7).

Field Testing of a Wet FGD Additive for Enhanced Mercury Control - Task 3 Full-scale Test Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gary Blythe

2007-05-01

This Topical Report summarizes progress on Cooperative Agreement DE-FC26-04NT42309, 'Field Testing of a Wet FGD Additive'. The objective of the project is to demonstrate the use of a flue gas desulfurization (FGD) additive, Degussa Corporation's TMT-15, to prevent the reemission of elemental mercury (Hg{sup 0}) in flue gas exiting wet FGD systems on coal-fired boilers. Furthermore, the project intends to demonstrate whether the additive can be used to precipitate most of the mercury (Hg) removed in the wet FGD system as a fine TMT salt that can be separated from the FGD liquor and bulk solid byproducts for separate disposal.more » The project is conducting pilot- and full-scale tests of the TMT-15 additive in wet FGD absorbers. The tests are intended to determine required additive dosages to prevent Hg{sup 0} reemissions and to separate mercury from the normal FGD byproducts for three coal types: Texas lignite/Power River Basin (PRB) coal blend, high-sulfur Eastern bituminous coal, and low-sulfur Eastern bituminous coal. The project team consists of URS Group, Inc., EPRI, TXU Generation Company LP, Southern Company, and Degussa Corporation. TXU Generation has provided the Texas lignite/PRB cofired test site for pilot FGD tests, Monticello Steam Electric Station Unit 3. Southern Company is providing the low-sulfur Eastern bituminous coal host site for wet scrubbing tests, as well as the pilot- and full-scale jet bubbling reactor (JBR) FGD systems to be tested. IPL, an AES company, provided the high-sulfur Eastern bituminous coal full-scale FGD test site and cost sharing. Degussa Corporation is providing the TMT-15 additive and technical support to the test program as cost sharing. The project is being conducted in six tasks. Of the six project tasks, Task 1 involves project planning and Task 6 involves management and reporting. The other four tasks involve field testing on FGD systems, either at pilot or full scale. The four tasks include: Task 2 - Pilot Additive

Berkeley Lab 2nd Grader Outreach

ScienceCinema

Scoggins, Jackie; Louie, Virginia

2017-12-11

The Berkeley Lab IT Department sponsored a community outreach program aimed at teaching young children about computers and networks. Second graders from LeConte Elementary School joined Lab IT Staff for a day of in-depth exercises and fun.

New clinical grading scales and objective measurement for conjunctival injection.

PubMed

Park, In Ki; Chun, Yeoun Sook; Kim, Kwang Gi; Yang, Hee Kyung; Hwang, Jeong-Min

2013-08-05

To establish a new clinical grading scale and objective measurement method to evaluate conjunctival injection. Photographs of conjunctival injection with variable ocular diseases in 429 eyes were reviewed. Seventy-three images with concordance by three ophthalmologists were classified into a 4-step and 10-step subjective grading scale, and used as standard photographs. Each image was quantified in four ways: the relative magnitude of the redness component of each red-green-blue (RGB) pixel; two different algorithms based on the occupied area by blood vessels (K-means clustering with LAB color model and contrast-limited adaptive histogram equalization [CLAHE] algorithm); and the presence of blood vessel edges, based on the Canny edge-detection algorithm. Area under the receiver operating characteristic curves (AUCs) were calculated to summarize diagnostic accuracies of the four algorithms. The RGB color model, K-means clustering with LAB color model, and CLAHE algorithm showed good correlation with the clinical 10-step grading scale (R = 0.741, 0.784, 0.919, respectively) and with the clinical 4-step grading scale (R = 0.645, 0.702, 0.838, respectively). The CLAHE method showed the largest AUC, best distinction power (P < 0.001, ANOVA, Bonferroni multiple comparison test), and high reproducibility (R = 0.996). CLAHE algorithm showed the best correlation with the 10-step and 4-step subjective clinical grading scales together with high distinction power and reproducibility. CLAHE algorithm can be a useful for method for assessment of conjunctival injection.

Labs: 1987.

ERIC Educational Resources Information Center

Igelsrud, Don, Ed.

1988-01-01

This article presents a variety of topics discussed in this column and at a biology teachers' workshop concerning the quality and value of lab techniques used for teaching high school biology. Topics included are Drosophila salivary glands, sea urchins, innovations, dyes and networking. (CW)

Systems for animal exposure in full-scale fire tests

NASA Technical Reports Server (NTRS)

Hilado, C. J.; Cumming, H. J.; Kourtides, D. A.; Parker, J. A.

1977-01-01

Two systems for exposing animals in full-scale fire tests are described. Both systems involve the simultaneous exposure of two animal species, mice and rats, in modular units; determination of mortality, morbidity, and behavioral response; and analysis of the blood for carboxyhemoglobin. The systems described represent two of many possible options for obtaining bioassay data from full-scale fire tests. In situations where the temperatures to which the test animals are exposed can not be controlled, analytical techniques may be more appropriate than bioassay techniques.

Berkeley Lab - Materials Sciences Division

Science.gov Websites

-486-6999 Urgent Radiation Protection Group Assistance Non-Life Threatening Event 24/7 Lab Phone: x7277 : 911 (no extentions required now) Non-Emergency Reporting (Fire and Police) Non-Life Threatening Event Spill Non-Life Threatening Event 24/7 Lab Phone: x6999 Cell Phone: 510-486-6999 Off Site Locations: 510

Report from the banding lab

USGS Publications Warehouse

Tautin, J.

1995-01-01

Mr. Tautin reported on the seemingly everchanging structure of biological science units within the Interior Department. Current Congressional proposals would either change the name of the Bird Banding Lab's parent agency or make it part of the Geological Survey. The current Congress has not looked favorably on science budgets within the Interior Department, and the Banding Lab's budget is being squeezed ever tighter.

Small-scale dynamic confinement gap test

NASA Astrophysics Data System (ADS)

Cook, Malcolm

2011-06-01

Gap tests are routinely used to ascertain the shock sensitiveness of new explosive formulations. The tests are popular since that are easy and relatively cheap to perform. However, with modern insensitive formulations with big critical diameters, large test samples are required. This can make testing and screening of new formulations expensive since large quantities of test material are required. Thus a new test that uses significantly smaller sample quantities would be very beneficial. In this paper we describe a new small-scale test that has been designed using our CHARM ignition and growth routine in the DYNA2D hydrocode. The new test is a modified gap test and uses detonating nitromethane to provide dynamic confinement (instead of a thick metal case) whilst exposing the sample to a long duration shock wave. The long duration shock wave allows less reactive materials that are below their critical diameter, more time to react. We present details on the modelling of the test together with some preliminary experiments to demonstrate the potential of the new test method.

Computer-based Astronomy Labs for Non-science Majors

NASA Astrophysics Data System (ADS)

Smith, A. B. E.; Murray, S. D.; Ward, R. A.

1998-12-01

We describe and demonstrate two laboratory exercises, Kepler's Third Law and Stellar Structure, which are being developed for use in an astronomy laboratory class aimed at non-science majors. The labs run with Microsoft's Excel 98 (Macintosh) or Excel 97 (Windows). They can be run in a classroom setting or in an independent learning environment. The intent of the labs is twofold; first and foremost, students learn the subject matter through a series of informational frames. Next, students enhance their understanding by applying their knowledge in lab procedures, while also gaining familiarity with the use and power of a widely-used software package and scientific tool. No mathematical knowledge beyond basic algebra is required to complete the labs or to understand the computations in the spreadsheets, although the students are exposed to the concepts of numerical integration. The labs are contained in Excel workbook files. In the files are multiple spreadsheets, which contain either a frame with information on how to run the lab, material on the subject, or one or more procedures. Excel's VBA macro language is used to automate the labs. The macros are accessed through button interfaces positioned on the spreadsheets. This is done intentionally so that students can focus on learning the subject matter and the basic spreadsheet features without having to learn advanced Excel features all at once. Students open the file and progress through the informational frames to the procedures. After each procedure, student comments and data are automatically recorded in a preformatted Lab Report spreadsheet. Once all procedures have been completed, the student is prompted for a filename in which to save their Lab Report. The lab reports can then be printed or emailed to the instructor. The files will have full worksheet and workbook protection, and will have a "redo" feature at the end of the lab for students who want to repeat a procedure.

My Green Car: The Adventure Begins (Ep. 1) – DOE Lab-Corps Video Series

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saxena, Samveg; Shah, Nihar; Hansen, Dana

One key difference between a great technology that stays in the lab and one that reaches the marketplace is customer interest. In Episode 1, the Lab’s MyGreenCar team gets ready to step outside the lab and test their technology’s value to consumers in a scientific way. What makes a new technology compelling enough to transition out of the lab and become a consumer product? That’s the question Berkeley Lab researchers Samveg Saxena, Nihar Shah, and Dana Hansen plus industry mentor Russell Carrington set out to answer for MyGreenCar, an app providing personalized fuel economy or electric vehicle range estimates formore » consumers researching new cars. DOE’s Lab-Corps program offered the technology team some answers. The EERE-funded program, based on the National Science Foundation’s I-Corps™ model for entrepreneurial training, provides tools and training to move energy-related inventions to the marketplace. During Lab-Corp’s intensive six-week session, technology teams interview 100 customer and value chain members to discover which potential products based on their technologies will have significant market pull. A six video series follows the MyGreenCar team’s Lab-Corps experience, from pre-training preparation with the Lab’s Innovation and Partnerships Office through the ups and downs of the customer discovery process. Will the app make it to the marketplace? You’ll just have to watch.« less

LS-DYNA Analysis of a Full-Scale Helicopter Crash Test

NASA Technical Reports Server (NTRS)

Annett, Martin S.

2010-01-01

A full-scale crash test of an MD-500 helicopter was conducted in December 2009 at NASA Langley's Landing and Impact Research facility (LandIR). The MD-500 helicopter was fitted with a composite honeycomb Deployable Energy Absorber (DEA) and tested under vertical and horizontal impact velocities of 26 ft/sec and 40 ft/sec, respectively. The objectives of the test were to evaluate the performance of the DEA concept under realistic crash conditions and to generate test data for validation of a system integrated LS-DYNA finite element model. In preparation for the full-scale crash test, a series of sub-scale and MD-500 mass simulator tests was conducted to evaluate the impact performances of various components, including a new crush tube and the DEA blocks. Parameters defined within the system integrated finite element model were determined from these tests. The objective of this paper is to summarize the finite element models developed and analyses performed, beginning with pre-test and continuing through post test validation.

The Rights and Responsibility of Test Takers When Large-Scale Testing Is Used for Classroom Assessment

ERIC Educational Resources Information Center

van Barneveld, Christina; Brinson, Karieann

2017-01-01

The purpose of this research was to identify conflicts in the rights and responsibility of Grade 9 test takers when some parts of a large-scale test are marked by teachers and used in the calculation of students' class marks. Data from teachers' questionnaires and students' questionnaires from a 2009-10 administration of a large-scale test of…

Field Testing of a Wet FGD Additive for Enhanced Mercury Control - Task 5 Full-Scale Test Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gary Blythe; MariJon Owens

2007-12-01

This Topical Report summarizes progress on Cooperative Agreement DE-FC26-04NT42309, 'Field Testing of a Wet FGD Additive'. The objective of the project is to demonstrate the use of two flue gas desulfurization (FGD) additives, Evonik Degussa Corporation's TMT-15 and Nalco Company's Nalco 8034, to prevent the re-emission of elemental mercury (Hg{sup 0}) in flue gas exiting wet FGD systems on coal-fired boilers. Furthermore, the project intends to demonstrate whether the additive can be used to precipitate most of the mercury (Hg) removed in the wet FGD system as a fine salt that can be separated from the FGD liquor and bulkmore » solid byproducts for separate disposal. The project is conducting pilot- and full-scale tests of the additives in wet FGD absorbers. The tests are intended to determine required additive dosages to prevent Hg{sup 0} re-emissions and to separate mercury from the normal FGD byproducts for three coal types: Texas lignite/Powder River Basin (PRB) coal blend, high-sulfur Eastern bituminous coal, and low-sulfur Eastern bituminous coal. The project team consists of URS Group, Inc., EPRI, Luminant Power (was TXU Generation Company LP), Southern Company, IPL (an AES company), Evonik Degussa Corporation and the Nalco Company. Luminant Power has provided the Texas lignite/PRB co-fired test site for pilot FGD tests and cost sharing. Southern Company has provided the low-sulfur Eastern bituminous coal host site for wet scrubbing tests, as well as the pilot- and full-scale jet bubbling reactor (JBR) FGD systems tested. IPL provided the high-sulfur Eastern bituminous coal full-scale FGD test site and cost sharing. Evonik Degussa Corporation is providing the TMT-15 additive, and the Nalco Company is providing the Nalco 8034 additive. Both companies are also supplying technical support to the test program as in-kind cost sharing. The project is being conducted in six tasks. Of the six project tasks, Task 1 involves project planning and Task 6 involves

Testing the equivalence principle on cosmological scales

NASA Astrophysics Data System (ADS)

Bonvin, Camille; Fleury, Pierre

2018-05-01

The equivalence principle, that is one of the main pillars of general relativity, is very well tested in the Solar system; however, its validity is more uncertain on cosmological scales, or when dark matter is concerned. This article shows that relativistic effects in the large-scale structure can be used to directly test whether dark matter satisfies Euler's equation, i.e. whether its free fall is characterised by geodesic motion, just like baryons and light. After having proposed a general parametrisation for deviations from Euler's equation, we perform Fisher-matrix forecasts for future surveys like DESI and the SKA, and show that such deviations can be constrained with a precision of order 10%. Deviations from Euler's equation cannot be tested directly with standard methods like redshift-space distortions and gravitational lensing, since these observables are not sensitive to the time component of the metric. Our analysis shows therefore that relativistic effects bring new and complementary constraints to alternative theories of gravity.

Using collaborative technologies in remote lab delivery systems for topics in automation

NASA Astrophysics Data System (ADS)

Ashby, Joe E.

Lab exercises are a pedagogically essential component of engineering and technology education. Distance education remote labs are being developed which enable students to access lab facilities via the Internet. Collaboration, students working in teams, enhances learning activity through the development of communication skills, sharing observations and problem solving. Web meeting communication tools are currently used in remote labs. The problem identified for investigation was that no standards of practice or paradigms exist to guide remote lab designers in the selection of collaboration tools that best support learning achievement. The goal of this work was to add to the body of knowledge involving the selection and use of remote lab collaboration tools. Experimental research was conducted where the participants were randomly assigned to three communication treatments and learning achievement was measured via assessments at the completion of each of six remote lab based lessons. Quantitative instruments used for assessing learning achievement were implemented, along with a survey to correlate user preference with collaboration treatments. A total of 53 undergraduate technology students worked in two-person teams, where each team was assigned one of the treatments, namely (a) text messaging chat, (b) voice chat, or (c) webcam video with voice chat. Each had little experience with the subject matter involving automation, but possessed the necessary technical background. Analysis of the assessment score data included mean and standard deviation, confirmation of the homogeneity of variance, a one-way ANOVA test and post hoc comparisons. The quantitative and qualitative data indicated that text messaging chat negatively impacted learning achievement and that text messaging chat was not preferred. The data also suggested that the subjects were equally divided on preference to voice chat verses webcam video with voice chat. To the end of designing collaborative

NASA AETC Test Technology Subproject

NASA Technical Reports Server (NTRS)

Bell, James

2017-01-01

Funds directed to improve measurement capabilities (pressure, force, flow, and temperature), test techniques and processes, and develop technologies critical to meeting NASA research needs and applicable to a multitude of facilities. Primarily works by funding small ($40K - $400K) tasks which result in a demonstration or initial capability of a new technology in an AETC facility.TT research and development tasks are generally TRL 3-6; they should be things which work in small scale or lab environments but need further development for use in production facilities.TT differs from CA in its focus on smaller-scale tasks and on instrumentation. Technologies developed by TT may become CA projects in order be fully realized within a facility.

LabVIEW: a software system for data acquisition, data analysis, and instrument control.

PubMed

Kalkman, C J

1995-01-01

Computer-based data acquisition systems play an important role in clinical monitoring and in the development of new monitoring tools. LabVIEW (National Instruments, Austin, TX) is a data acquisition and programming environment that allows flexible acquisition and processing of analog and digital data. The main feature that distinguishes LabVIEW from other data acquisition programs is its highly modular graphical programming language, "G," and a large library of mathematical and statistical functions. The advantage of graphical programming is that the code is flexible, reusable, and self-documenting. Subroutines can be saved in a library and reused without modification in other programs. This dramatically reduces development time and enables researchers to develop or modify their own programs. LabVIEW uses a large amount of processing power and computer memory, thus requiring a powerful computer. A large-screen monitor is desirable when developing larger applications. LabVIEW is excellently suited for testing new monitoring paradigms, analysis algorithms, or user interfaces. The typical LabVIEW user is the researcher who wants to develop a new monitoring technique, a set of new (derived) variables by integrating signals from several existing patient monitors, closed-loop control of a physiological variable, or a physiological simulator.

Unique Approach to Hydraulic Characterization at an Underground Lab

NASA Astrophysics Data System (ADS)

Jones, T. L.; Wang, J. S.

2009-12-01

The Sanford Underground Laboratory is the interim lab for the future federally funded DUSEL (Deep Underground Science and Engineering Lab). The Sanford Lab took over the abandoned Homestake mine in Lead, SD. Over three hundred miles of drift, extending 8,000 feet below the surface, are now being used to house experiments in disciplines including physics, geology, and biology. The lab is situated in Precambrian metamorphic rocks intersected by Tertiary dike swarms. Three relevant geologic units are defined within the Precambrian rock system; all of which are interpreted to be metamorphosed igneous and sedimentary deposits. The Sanford Lab provides a unique environment to study several aspects of hydrogeology and hydrology; including geochemistry, hydraulic systems in fractured aquifers, and fluvial activity within mine workings. Aquifer characteristics housing the mine workings’ is important to define for future and present research at the underground lab. Outlined here is a unique approach to defining the matrix porosity within the fractured aquifer system. The Homestake mine was abandoned and the pump system keeping the mine dry was turned off in 2003. Over the course of the next five years the water level rose 3470 feet. Oxidation of iron from the water left a red staining on the submerged rocks. Hydrological observations are conducted on different levels throughout the Homestake facility as the water levels are lowered. Isolated air pockets and long stretches of unstained areas along the roof of drifts have been observed, together with less frequent occurrences of seepages. These observations are documented to supplement hydrological monitoring and testing with sensors. The sizes and widths of the trapped air pockets are indications of low permeability values and can be used to estimate the degree of heterogeneity along drifts. It is noted that sections of long stretches of trapped air have more delayed drainages, consistent with low effective permeability

Innovation - A view from the Lab

USDA-ARS?s Scientific Manuscript database

The USDA Ag Lab in Peoria helps bridge the gap between agricultural producers and commercial manufacturers. In 2015, the Ag Lab, officially known as the Agricultural Research Service (ARS) National Center for Agricultural Utilization Research (NCAUR), is celebrating 75 years of research in Peoria. T...

Recent lab-on-chip developments for novel drug discovery.

PubMed

Khalid, Nauman; Kobayashi, Isao; Nakajima, Mitsutoshi

2017-07-01

Microelectromechanical systems (MEMS) and micro total analysis systems (μTAS) revolutionized the biochemical and electronic industries, and this miniaturization process became a key driver for many markets. Now, it is a driving force for innovations in life sciences, diagnostics, analytical sciences, and chemistry, which are called 'lab-on-a-chip, (LOC)' devices. The use of these devices allows the development of fast, portable, and easy-to-use systems with a high level of functional integration for applications such as point-of-care diagnostics, forensics, the analysis of biomolecules, environmental or food analysis, and drug development. In this review, we report on the latest developments in fabrication methods and production methodologies to tailor LOC devices. A brief overview of scale-up strategies is also presented together with their potential applications in drug delivery and discovery. The impact of LOC devices on drug development and discovery has been extensively reviewed in the past. The current research focuses on fast and accurate detection of genomics, cell mutations and analysis, drug delivery, and discovery. The current research also differentiates the LOC devices into new terminology of microengineering, like organ-on-a-chip, stem cells-on-a-chip, human-on-a-chip, and body-on-a-chip. Key challenges will be the transfer of fabricated LOC devices from lab-scale to industrial large-scale production. Moreover, extensive toxicological studies are needed to justify the use of microfabricated drug delivery vehicles in biological systems. It will also be challenging to transfer the in vitro findings to suitable and promising in vivo models. WIREs Syst Biol Med 2017, 9:e1381. doi: 10.1002/wsbm.1381 For further resources related to this article, please visit the WIREs website. © 2017 Wiley Periodicals, Inc.

Evaluation and recommendations for work group integration within the Materials and Processes Lab

NASA Technical Reports Server (NTRS)

Farrington, Phillip A.

1992-01-01

The goal of this study was to evaluate and make recommendations for improving the level of integration of several work groups within the Materials and Processes Lab at the Marshall Space Flight Center. This evaluation has uncovered a variety of projects that could improve the efficiency and operation of the work groups as well as the overall integration of the system. In addition, this study provides the foundation for specification of a computer integrated manufacturing test bed environment in the Materials and Processes Lab.

H CANYON PROCESSING IN CORRELATION WITH FH ANALYTICAL LABS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weinheimer, E.

2012-08-06

Management of radioactive chemical waste can be a complicated business. H Canyon and F/H Analytical Labs are two facilities present at the Savannah River Site in Aiken, SC that are at the forefront. In fact H Canyon is the only large-scale radiochemical processing facility in the United States and this processing is only enhanced by the aid given from F/H Analytical Labs. As H Canyon processes incoming materials, F/H Labs provide support through a variety of chemical analyses. Necessary checks of the chemical makeup, processing, and accountability of the samples taken from H Canyon process tanks are performed at themore » labs along with further checks on waste leaving the canyon after processing. Used nuclear material taken in by the canyon is actually not waste. Only a small portion of the radioactive material itself is actually consumed in nuclear reactors. As a result various radioactive elements such as Uranium, Plutonium and Neptunium are commonly found in waste and may be useful to recover. Specific processing is needed to allow for separation of these products from the waste. This is H Canyon's specialty. Furthermore, H Canyon has the capacity to initiate the process for weapons-grade nuclear material to be converted into nuclear fuel. This is one of the main campaigns being set up for the fall of 2012. Once usable material is separated and purified of impurities such as fission products, it can be converted to an oxide and ultimately turned into commercial fuel. The processing of weapons-grade material for commercial fuel is important in the necessary disposition of plutonium. Another processing campaign to start in the fall in H Canyon involves the reprocessing of used nuclear fuel for disposal in improved containment units. The importance of this campaign involves the proper disposal of nuclear waste in order to ensure the safety and well-being of future generations and the environment. As processing proceeds in the fall, H Canyon will have a

LABS Foundational Technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Olson, Jerry

2012-01-01

They are the inventors of our generation dedicated to exceptional science, advancing the technologies of tomorrow. CO-LABS honors the outstanding achievements of researchers and their impact on the world.

Aligning Scales of Certification Tests. Research Report. ETS RR-10-07

ERIC Educational Resources Information Center

Dorans, Neil J.; Liang, Longjuan; Puhan, Gautam

2010-01-01

Scores are the most visible and widely used products of a testing program. The choice of score scale has implications for test specifications, equating, and test reliability and validity, as well as for test interpretation. At the same time, the score scale should be viewed as infrastructure likely to require repair at some point. In this report…

Testing for Starch, Respiring Tissues, and Vascular Bundles: Inquiry-Based Seed and Stem Anatomy Labs.

ERIC Educational Resources Information Center

Florine, Sara; Hammond, Paul; Pomart, Katrina; Balschweid, Mark

2002-01-01

Describes some inquiry-based labs in which students identify starch in popped popcorn, then determine whether starch is present in the kernels prior to them being cooked. Students distinguish monocot and dicot stems as well as determining whether boiling kills tissues in seeds that have been soaked in water. (DDR)

High-Stakes Accountability: Student Anxiety and Large-Scale Testing

ERIC Educational Resources Information Center

von der Embse, Nathaniel P.; Witmer, Sara E.

2014-01-01

This study examined the relationship between student anxiety about high-stakes testing and their subsequent test performance. The FRIEDBEN Test Anxiety Scale was administered to 1,134 11th-grade students, and data were subsequently collected on their statewide assessment performance. Test anxiety was a significant predictor of test performance…

Investigation of correlation between full-scale and fifth-scale wind tunnel tests of a Bell helicopter Textron Model 222

NASA Technical Reports Server (NTRS)

Squires, P. K.

1982-01-01

Reasons for lack of correlation between data from a fifth-scale wind tunnel test of the Bell Helicopter Textron Model 222 and a full-scale test of the model 222 prototype in the NASA Ames 40-by 80-foot tunnel were investigated. This investigation centered around a carefully designed fifth-scale wind tunnel test of an accurately contoured model of the Model 222 prototype mounted on a replica of the full-scale mounting system. The improvement in correlation for drag characteristics in pitch and yaw with the fifth-scale model mounted on the replica system is shown. Interference between the model and mounting system was identified as a significant effect and was concluded to be a primary cause of the lack of correlation in the earlier tests.

Ares I Scale Model Acoustic Test Instrumentation for Acoustic and Pressure Measurements

NASA Technical Reports Server (NTRS)

Vargas, Magda B.; Counter, Douglas

2011-01-01

Ares I Scale Model Acoustic Test (ASMAT) is a 5% scale model test of the Ares I vehicle, launch pad and support structures conducted at MSFC to verify acoustic and ignition environments and evaluate water suppression systems Test design considerations 5% measurements must be scaled to full scale requiring high frequency measurements Users had different frequencies of interest Acoustics: 200 - 2,000 Hz full scale equals 4,000 - 40,000 Hz model scale Ignition Transient: 0 - 100 Hz full scale equals 0 - 2,000 Hz model scale Environment exposure Weather exposure: heat, humidity, thunderstorms, rain, cold and snow Test environments: Plume impingement heat and pressure, and water deluge impingement Several types of sensors were used to measure the environments Different instrument mounts were used according to the location and exposure to the environment This presentation addresses the observed effects of the selected sensors and mount design on the acoustic and pressure measurements

Home Healthcare Nurses' Job Satisfaction Scale: refinement and psychometric testing.

PubMed

Ellenbecker, Carol H; Byleckie, James J

2005-10-01

This paper describes a study to further develop and test the psychometric properties of the Home Healthcare Nurses' Job Satisfaction Scale, including reliability and construct and criterion validity. Numerous scales have been developed to measure nurses' job satisfaction. Only one, the Home Healthcare Nurses' Job Satisfaction Scale, has been designed specifically to measure job satisfaction of home healthcare nurses. The Home Healthcare Nurses' Job Satisfaction Scale is based on a theoretical model that integrates the findings of empirical research related to job satisfaction. A convenience sample of 340 home healthcare nurses completed the Home Healthcare Nurses' Job Satisfaction Scale and the Mueller and McCloskey Satisfaction Scale, which was used to test criterion validity. Factor analysis was used for testing and refinement of the theory-based assignment of items to constructs. Reliability was assessed by Cronbach's alpha internal consistency reliability coefficients. The data were collected in 2003. Nine factors contributing to home healthcare nurses' job satisfaction emerged from the factor analysis and were strongly supported by the underlying theory. Factor loadings were all above 0.4. Cronbach's alpha coefficients for each of the nine subscales ranged from 0.64 to 0.83; the alpha for the global scale was 0.89. The correlations between the Home Healthcare Nurses' Job Satisfaction Scale and Mueller and McCloskey Satisfaction Scale was 0.79, indicating good criterion-related validity. The Home Healthcare Nurses' Job Satisfaction Scale has potential as a reliable and valid scale for measurement of job satisfaction of home healthcare nurses.

Berkeley Lab - Materials Sciences Division

Science.gov Websites

Berkeley Lab Berkeley Lab A-Z Index Phone Book Jobs Search DOE Search MSD Go MSD - Materials Investigators Ager, Joel W » Alivisatos, A Paul » Altman, Ehud » Analytis, James » Anderson, Christopher  , Naomi » Gullikson, Eric M » Harris, Stephen J » Hasan, M. Zahid » Hellman, Frances » Helms, Brett A

Experiential Learning of Digital Communication Using LabVIEW

ERIC Educational Resources Information Center

Zhan, Wei; Porter, Jay R.; Morgan, Joseph A.

2014-01-01

This paper discusses the design and implementation of laboratories and course projects using LabVIEW in an instrumentation course. The pedagogical challenge is to enhance students' learning of digital communication using LabVIEW. LabVIEW was extensively used in the laboratory sessions, which better prepared students for the course projects. Two…

Small-scale fixed wing airplane software verification flight test

NASA Astrophysics Data System (ADS)

Miller, Natasha R.

The increased demand for micro Unmanned Air Vehicles (UAV) driven by military requirements, commercial use, and academia is creating a need for the ability to quickly and accurately conduct low Reynolds Number aircraft design. There exist several open source software programs that are free or inexpensive that can be used for large scale aircraft design, but few software programs target the realm of low Reynolds Number flight. XFLR5 is an open source, free to download, software program that attempts to take into consideration viscous effects that occur at low Reynolds Number in airfoil design, 3D wing design, and 3D airplane design. An off the shelf, remote control airplane was used as a test bed to model in XFLR5 and then compared to flight test collected data. Flight test focused on the stability modes of the 3D plane, specifically the phugoid mode. Design and execution of the flight tests were accomplished for the RC airplane using methodology from full scale military airplane test procedures. Results from flight test were not conclusive in determining the accuracy of the XFLR5 software program. There were several sources of uncertainty that did not allow for a full analysis of the flight test results. An off the shelf drone autopilot was used as a data collection device for flight testing. The precision and accuracy of the autopilot is unknown. Potential future work should investigate flight test methods for small scale UAV flight.

An LED solar simulator for student labs

NASA Astrophysics Data System (ADS)

González, Manuel I.

2017-05-01

Measuring voltage-current and voltage-power curves of a photovoltaic module is a nice experiment for high school and undergraduate students. In labs where real sunlight is not available this experiment requires a solar simulator. A prototype of a simulator using LED lamps has been manufactured and tested, and a comparison with classical halogen simulators has been performed. It is found that LED light offers lower levels of irradiance, but much better performance in terms of module output for a given irradiance.

Practical Physics Labs: A Resource Manual.

ERIC Educational Resources Information Center

Goodwin, Peter

This resource manual focuses on physics labs that relate to the world around us and utilize simple equipment and situations. Forty-five laboratories are included that relate to thermodynamics, electricity, magnetism, dynamics, optics, wave transmission, centripetal force, and atomic physics. Each lab has three sections. The first section…

Injection and injection-compression moulding replication capability for the production of polymer lab-on-a-chip with nano structures

NASA Astrophysics Data System (ADS)

Calaon, M.; Tosello, G.; Garnaes, J.; Hansen, H. N.

2017-10-01

The manufacturing precision and accuracy in the production of polymer lab-on-a-chip components with 100-130 nm deep nanochannels are evaluated using a metrological approach. Replication fidelity on corresponding process fingerprint test nanostructures over different substrates (nickel tool and polymer part) is quantified through traceable atomic force microscope measurements. Dimensions of injection moulded (IM) and injection-compression moulded (ICM) thermoplastic cyclic olefin copolymer nanofeatures are characterized depending on process parameters and four different features positions on a 30  ×  80 mm2 area. Replication capability of IM and ICM technologies are quantified and the products tolerance at the nanometre dimensional scale verified.

Large scale cryogenic fluid systems testing

NASA Technical Reports Server (NTRS)

1992-01-01

NASA Lewis Research Center's Cryogenic Fluid Systems Branch (CFSB) within the Space Propulsion Technology Division (SPTD) has the ultimate goal of enabling the long term storage and in-space fueling/resupply operations for spacecraft and reusable vehicles in support of space exploration. Using analytical modeling, ground based testing, and on-orbit experimentation, the CFSB is studying three primary categories of fluid technology: storage, supply, and transfer. The CFSB is also investigating fluid handling, advanced instrumentation, and tank structures and materials. Ground based testing of large-scale systems is done using liquid hydrogen as a test fluid at the Cryogenic Propellant Tank Facility (K-site) at Lewis' Plum Brook Station in Sandusky, Ohio. A general overview of tests involving liquid transfer, thermal control, pressure control, and pressurization is given.

My Brother’s Keeper National Lab Week

NASA Image and Video Library

2016-03-02

Students in the My Brother’s Keeper program line the railings of an observation deck overlooking the Granular Mechanics and Regolith Operations Lab at NASA’s Kennedy Space Center in Florida. The spaceport is one of six NASA centers that participated in My Brother’s Keeper National Lab Week. The event is a nationwide effort to bring youth from underrepresented communities into federal labs and centers for hands-on activities, tours and inspirational speakers. Sixty students from the nearby cities of Orlando and Sanford visited Kennedy, where they toured the Vehicle Assembly Building, the Space Station Processing Facility and the center’s innovative Swamp Works Labs. The students also had a chance to meet and ask questions of a panel of subject matter experts from across Kennedy.

My Brother’s Keeper National Lab Week

NASA Image and Video Library

2016-03-02

Students in the My Brother’s Keeper program try out some of the machinery inside the Prototype Lab at NASA’s Kennedy Space Center. The Florida spaceport is one of six NASA centers that participated in My Brother’s Keeper National Lab Week. The event is a nationwide effort to bring youth from underrepresented communities into federal labs and centers for hands-on activities, tours and inspirational speakers. Sixty students from the nearby cities of Orlando and Sanford visited Kennedy, where they toured the Vehicle Assembly Building, the Space Station Processing Facility and the center’s innovative Swamp Works Labs. The students also had a chance to meet and ask questions of a panel of subject matter experts from across Kennedy.

My Brother’s Keeper National Lab Week

NASA Image and Video Library

2016-03-02

Mike Lane demonstrates a 3D scanner inside the NASA Kennedy Space Center Prototype Lab for students in the My Brother’s Keeper program. The Florida spaceport is one of six NASA centers that participated in My Brother’s Keeper National Lab Week. The event is a nationwide effort to bring youth from underrepresented communities into federal labs and centers for hands-on activities, tours and inspirational speakers. Sixty students from the nearby cities of Orlando and Sanford visited Kennedy, where they toured the Vehicle Assembly Building, the Space Station Processing Facility and the center’s innovative Swamp Works Labs. The students also had a chance to meet and ask questions of a panel of subject matter experts from across Kennedy.

My Brother’s Keeper National Lab Week

NASA Image and Video Library

2016-03-02

Harold (Russ) McAmis demonstrates machinery inside NASA Kennedy Space Center’s Prototype Lab for students in the My Brother’s Keeper program. The Florida spaceport is one of six NASA centers that participated in My Brother’s Keeper National Lab Week. The event is a nationwide effort to bring youth from underrepresented communities into federal labs and centers for hands-on activities, tours and inspirational speakers. Sixty students from the nearby cities of Orlando and Sanford visited Kennedy, where they toured the Vehicle Assembly Building, the Space Station Processing Facility and the center’s innovative Swamp Works Labs. The students also had a chance to meet and ask questions of a panel of subject matter experts from across Kennedy.

My Brother’s Keeper National Lab Week

NASA Image and Video Library

2016-03-02

Jose Nunez of NASA Kennedy Space Center’s Exploration Research and Technology Programs talks to students in the My Brother’s Keeper program outside the Florida spaceport’s Swamp Works Lab. Kennedy is one of six NASA centers that participated in My Brother’s Keeper National Lab Week. The event is a nationwide effort to bring youth from underrepresented communities into federal labs and centers for hands-on activities, tours and inspirational speakers. Sixty students from the nearby cities of Orlando and Sanford visited Kennedy, where they toured the Vehicle Assembly Building, the Space Station Processing Facility and the center’s innovative Swamp Works Labs. The students also had a chance to meet and ask questions of a panel of subject matter experts from across Kennedy.

Where Lab Tests Are Performed

MedlinePlus

... Time and International Normalized Ratio (PT/INR) PSEN1 Quantitative Immunoglobulins Red Blood Cell (RBC) Antibody Identification Red ... Accessed June 2011. Genetics and Public Policy Center. Survey of Direct-to-Consumer Testing Statutes and Regulations. ...

Ensuring Positiveness of the Scaled Difference Chi-Square Test Statistic

ERIC Educational Resources Information Center

Satorra, Albert; Bentler, Peter M.

2010-01-01

A scaled difference test statistic T[tilde][subscript d] that can be computed from standard software of structural equation models (SEM) by hand calculations was proposed in Satorra and Bentler (Psychometrika 66:507-514, 2001). The statistic T[tilde][subscript d] is asymptotically equivalent to the scaled difference test statistic T[bar][subscript…

My Green Car: The Adventure Begins (Ep. 1) – DOE Lab-Corps Video Series

ScienceCinema

Saxena, Samveg; Shah, Nihar; Hansen, Dana

2018-06-12

One key difference between a great technology that stays in the lab and one that reaches the marketplace is customer interest. In Episode 1, the Lab’s MyGreenCar team gets ready to step outside the lab and test their technology’s value to consumers in a scientific way. What makes a new technology compelling enough to transition out of the lab and become a consumer product? That’s the question Berkeley Lab researchers Samveg Saxena, Nihar Shah, and Dana Hansen plus industry mentor Russell Carrington set out to answer for MyGreenCar, an app providing personalized fuel economy or electric vehicle range estimates for consumers researching new cars. DOE’s Lab-Corps program offered the technology team some answers. The EERE-funded program, based on the National Science Foundation’s I-Corps™ model for entrepreneurial training, provides tools and training to move energy-related inventions to the marketplace. During Lab-Corp’s intensive six-week session, technology teams interview 100 customer and value chain members to discover which potential products based on their technologies will have significant market pull. A six video series follows the MyGreenCar team’s Lab-Corps experience, from pre-training preparation with the Lab’s Innovation and Partnerships Office through the ups and downs of the customer discovery process. Will the app make it to the marketplace? You’ll just have to watch.