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Sample records for labial frenum

  1. Using the diode laser in the lower labial frenum removal

    PubMed Central

    GARGARI, M.; AUTILI, N.; PETRONE, A.; PRETE, V.

    2012-01-01

    Summary Using the diode laser in the lower labial frenum removal. Objective The aim of this study is to assess the advantages of the use of diode laser to removal inferior labial frenum. Methods The treatment with the diode laser was proposed to a female patient of 32 years old in good general health having an abnormal inferior labial frenum that causes retracting of the gingival margin. The incision was carried out with diode laser at a wavelength of 940 nm and was removed the frenum mucosa and the deep tissue constitute of connective fiber and muscle fiber. Before the surgery wasn’t used the local anesthetic and after the cutting wasn’t necessary the use of suture. Results The wound had a good healing without scar. The patient didn’t have pain and bleeding during the healing and she didn’t report complications. It wasn’t necessary the use of antibiotic and anti-inflammatory. Conclusions The use of lasers has proved effective in the removal of labial frenum because it offers several advantages for the patient than traditional surgery. PMID:23285407

  2. Esthetic management of the upper labial frenum: a novel frenectomy technique.

    PubMed

    Bagga, Sukhchain; Bhat, K Mahalinga; Bhat, G Subraya; Thomas, Betsy S

    2006-01-01

    An abnormal upper labial frenum is capable of retracting the gingival margin, creating a diastema, limiting lip movement, and in cases of a high smile line, affecting esthetics also. When an abnormal frenum is present, frenectomy is advised. This technique has been modified in many ways. But in most of the techniques the zone of attached gingiva and esthetics are not considered. This case report highlights a new technique of frenectomy that results in good esthetics, excellent color match, gain in attached gingiva, and healing by primary intention at the site of the thick, extensive abnormal frenum.

  3. Diagnosing and understanding the maxillary lip-tie (superior labial, the maxillary labial frenum) as it relates to breastfeeding.

    PubMed

    Kotlow, Lawrence A

    2013-11-01

    Successful breastfeeding is dependent upon an infant's ability to correctly latch onto a mother's breast. If an infant is born with oral soft tissue abnormalities such as tongue-tie or lip-tie, breastfeeding may become challenging or impossible. During the oral evaluation of an infant presenting with breastfeeding problems, one area that is often overlooked and undiagnosed and, thus, untreated is the attachment of the upper lip to the maxillary gingival tissue. Historically, this tissue has been described as the superior labial frenum, median labial frenum, or maxillary labial frenum. These terms all refer to a segment of the mucous membrane in the midline of the upper lip containing loose connective tissue that inserts into the maxillary arch's loose, unattached gingival or tight, attached gingival tissue. There is no muscle contained within this tissue. In severe instances, this tissue may extend into the area behind the upper central incisors and incisive papilla. The author has defined and identified the restrictions of mobility of this tissue as a lip-tie, which reflects the clinical attachment of the upper lip to the maxillary arch. This article discusses the diagnosis and classifications of the lip-tie, as it affects an infant's latch onto the mother's breast. As more and more women choose to breastfeed, lip-ties must be considered as an impediment to breastfeeding, recognizing that they can affect a successful, painless latch and milk transfer.

  4. Ectopic eruption of maxillary central incisor through abnormally thickened labial frenum: An unusual presentation.

    PubMed

    Gugnani, Neeraj; Pandit, I K; Gupta, Monika; Gugnani, Shalini; Vishnoi, Ashmi; Sabharwal, Ozasvita; Manhas, Swati

    2017-01-01

    Ectopic eruption is a deviation from the normal eruption pattern, making the tooth erupt out of its normal position, and possibly causing resorption of adjacent primary teeth. A wide range of etiological factors may be responsible for ectopic eruption of the teeth, so their management depends on the correction of the established etiological factor. The present case report describes an unusual case of ectopically erupted central incisor encased within an abnormally thickened labial frenum, which was treated by orthodontic repositioning of the ectopically erupting tooth after frenectomy.

  5. Er,Cr:YSGG laser labial frenectomy: a clinical retrospective evaluation of 156 consecutive cases.

    PubMed

    Olivi, Giovanni; Chaumanet, Gilles; Genovese, Maria Daniela; Beneduce, Carla; Andreana, Sebastiano

    2010-01-01

    The labial frenum may impede oral hygiene and result in diastema between anterior teeth and traction of the attached gingiva. Surgical removal of the frenum during puberty has been recommended for these patients. This article clinically evaluates the efficacy of an Er,Cr:YSGG laser in removing the labial frenum in an adolescent and pre-pubescent population. Using an Er,Cr:YSGG laser at a power setting of 1.5 W or less and 20 to 30 pulses per second, a total of 156 frenectomies were performed on 143 children. Patients returned for recall visits at 3, 7, 21, and 30 days and at one, two, and three years. Surgical areas were checked for adverse events, recurrency of frenum, and functional complications. Patient acceptance was also evaluated by using the Wong-Baker FACES pain rating scale. Thirteen recurrences were reported in the adolescent population at 21 or 30 days, all of which required re-intervention; however, only two cases displayed recurrence of the frenum. None of the three pre-pubescent cases required additional intervention, maintaining acceptable clinical results after three years. Patient acceptance was very high, and no postoperative adverse events were reported.

  6. The diastema, the frenum, the frenectomy: a clinical study.

    PubMed

    Edwards, J G

    1977-05-01

    1. The pretreatment relationship between a clinically "abnormal"-appearing maxillary midline frenum and a midline diastema showed a strong, but not absolute, correlation. A certain percentage of patients demonstrated (1) a diastema but not an "abnormal" frenum or (2) no diastema but an "abnormal" frenum. 2. Diastema cases in which there were "abnormal" pretreatment frenums demonstrated a decidedly stronger potential for relapse after orthodontic closure. The exceptions to the rule were explained by the clinician's inability to differentiate between "normal" and "abnormal" frenums and by the periodontium's apparent (if not consistent) ability to recognize the frenal and interdental tissues following orthodontic tooth movement. 3. A three-stage surgical procedure was shown to be very effective in alleviating the relapse phenomenon following orthodontic treatment of diastemas. The surgical procedures were successful in avoiding many of the hazards to the periodontium associated with previous techniques.

  7. Use of CO2 laser in lingual and labial frenectomy

    NASA Astrophysics Data System (ADS)

    Fiorotti, Renata C.; Bellini, Bruno S.; Cassitas, Nilceu P.; Baldin, Diva H. Z.; Nicola, Ester M. D.

    2000-03-01

    Ankiloglossia or frenum lingual alteration leads to important tongue dysfunction, which, besides discomfort and pain during function, is generally responsible for the difficulty to express specific phonemes. In other cases, a heavy muscular abnormal attachment of labial frenum can promote clinical changes. In such case, an eventual orthodontic therapy is indicated and aesthetic alteration is observed. In both cases, surgical removal is indicated. The surgery, for prevention purposes, must be done as soon as possible, but considering that the majority of patients are young (5 - 14 years old), difficulties during surgery are expected to occur. Correction of speech or orthodontic dysfunction in advanced ages is much more complex and difficult than in childhood. In the present work we demonstrate that the use of CO2 lasers in these cases are advantageous and simple. The laser energy causes the tissue of the frenum to open in the classic shape with no bleeding and no need for suture, reducing the risk of cross- contamination and of postoperative infection. Scarring and other complications are also minimized. A CO2 laser (continuous, 8 W, 10.6 micrometers) was used assisted with local anesthesia. The major advantage of laser is the possibility of its application in early ages, preventing further problems.

  8. Surgery Management of Rare Hypertrophic Frenum in an Infant

    PubMed Central

    Stroppa, Sheila de Carvalho; da Silva, Juliana Yassue Barbosa; Tavares, Maria Cristina Reis; Duda, João Gilberto; Losso, Estela Maris

    2014-01-01

    To report a rare case of a lateral frenum hypertrophy in an infant, this paper describes the case of a girl who came to a first dental appointment when she was 4 months old. A hypertrophic lateral frenum in the upper left canine region was detected. A great depression in the gingival rodet separated the anterior maxillary segment from the posterior one and also decreased the lip mobility in this region. A frenectomy was performed when the patient was 11 months old and the clinical follow-up was done up to the age of 30 months. There was normalization in the vestibular insertion of the lateral frenum, lip mobility, physiological development of the maxilla, and eruption of the upper incisors, canines, and first primary molars. Infants should go to a dental examination precociously in order to detect possible congenital and development alterations. PMID:25180104

  9. Surgery management of rare hypertrophic frenum in an infant.

    PubMed

    Stroppa, Sheila de Carvalho; da Silva, Juliana Yassue Barbosa; Tavares, Maria Cristina Reis; Duda, João Gilberto; Losso, Estela Maris

    2014-01-01

    To report a rare case of a lateral frenum hypertrophy in an infant, this paper describes the case of a girl who came to a first dental appointment when she was 4 months old. A hypertrophic lateral frenum in the upper left canine region was detected. A great depression in the gingival rodet separated the anterior maxillary segment from the posterior one and also decreased the lip mobility in this region. A frenectomy was performed when the patient was 11 months old and the clinical follow-up was done up to the age of 30 months. There was normalization in the vestibular insertion of the lateral frenum, lip mobility, physiological development of the maxilla, and eruption of the upper incisors, canines, and first primary molars. Infants should go to a dental examination precociously in order to detect possible congenital and development alterations.

  10. Interventions in the Alteration on Lingual Frenum: Systematic Review

    PubMed Central

    Miranda, Priscilla Poliseni; Cardoso, Carolina Louise; Gomes, Erissandra

    2015-01-01

    Introduction  Altered lingual frenum modifies the normal tongue mobility, which may influence the stomatognathic functions, resulting in anatomical, physiological and social damage to the subject. It is necessary that health professionals are aware of the process of evaluation, diagnostics and treatment used today, guiding their intervention. Objective  To perform a systematic review of what are the treatment methods used in cases of lingual frenum alteration. Data Synthesis  The literature searches were conducted in MEDLINE, LILACS, SciELO, Cochrane and IBECS, delimited by language (Portuguese, English, Spanish), date of publication (January 2000 to January 2014) and studies performed in humans. The selection order used to verify the eligibility of the studies were related to: full text availability; review the abstract; text analysis; final selection. Of the total 443 publications, 26 remained for analysis. The surgical approach was used in all studies, regardless of the study population (infants, children and adults), with a range of tools and techniques employed; speech therapy was recommended in the post surgical in 4 studies. Only 4 studies, all with infants, showed scientific evidence. Conclusion  Surgical intervention is effective for the remission of the limitations caused by the alteration on lingual frenum, but there is a deficit of studies with higher methodological quality. The benefits of speech therapy in the post surgical period are described from improvement in the language of mobility aspects and speech articulation. PMID:27413412

  11. Hamular frenum modification: a removable denture prosthesis retention and stability enhancement.

    PubMed

    Massad, J J; Anderson, J F

    2001-04-01

    A removable denture prosthesis, whether partial or complete, often requires preprosthetic surgery to achieve optimum stabilization and retention. While the hamular frenum may produce significant dynamic dislodging forces, a literature review did not reveal any reports dealing with this problem. A hamular frenum reduction surgical procedure using the free autogenous gingival graft procedure is described. Prosthetic function may be enhanced by eliminating the dynamic disrupting force of the hamular frenum along with improving posterior maxillary tuberosity contour and, as necessary, premaxillary form, allowing these contours to work in concert to develop a "cupping" stabilizing and retentive complex.

  12. [Histomorphologic evaluation of upper lip frenum in relation to the method of treating diastema].

    PubMed

    Ziemba, Zygmunt

    2003-01-01

    The aim of this study was to determine collagen density in the hypertrophic upper lip frenum and scar forming after frenectomy and to compare the results with collagen density in a normal population (autopsy specimens). Differences in collagen density may cause problems in diastema closure and may eventually result in relapse of this condition. The study was done in 47 patients treated for diastema. Histomorphology was performed in 15 patients of this group. Autopsy material was obtained from 27 persons. Histomorphometric assessment of collagen density was done after staining of collagen fibers according to van Gieson. A computerized image analysis system was used for interactive detection of stained collagen fibers on the digitized microscopic image. The percentage of positive staining expressed as ratio of positive area to whole area of the field studied was determined and recorded as an Excel file. Collagen density was increased in the pathologic frenum and in the scar as compared with the normal frenum. The difference was statistically significant. Diastema treatment with frenectomy, fixed appliance and retainer produced more stable results as compared to treatment with a removable appliance without frenectomy. The results suggest that the similar collagen density observed in hypertrophic upper lip frenum and scar after frenetomy may hinder complete closure of diastema and facilitate relapse after treatment.

  13. A labial gesture for /l/

    NASA Astrophysics Data System (ADS)

    Campbell, Fiona; Gick, Bryan

    2003-04-01

    Both in language change and in substitutions during language acquisition and disordered speech, /l/ has often been observed to alternate with labial sounds such as [w] or rounded vowels, particularly in postvocalic position. While there are many possible explanations for this alternation, including acoustic enhancement and articulator coupling, one possibility that has not been tested is whether normal adult speakers of English actually produce lip rounding for /l/. A study was conducted to test for the presence of a labial gesture in normal productions of /l/. Front and side video data of lip positions were collected from three adult English speakers during productions of /l/ and /d/. Significant differences were found for all subjects in lip protrusion (upper and lower) and/or lip aperture (horizontal and vertical) in post-vocalic allophones, as well as between the pre- and post-vocalic allophones of /l/. No significant differences were observed in comparisons of pre-vocalic /l/ and /d/. Results suggest that there is in fact a labial gesture in the post-vocalic allophone of /l/, but not in the pre-vocalic allophone. These findings are consistent with a notion of gestural simplification as a possible explanation for substitutions and in language change. [Research supported by NSERC.

  14. Labial ankyloglossia: A rare case report

    PubMed Central

    Bahadure, Rakesh Namdeo; Jain, Eesha; Singh, Parul; Pandey, Rameshkumar; Chuk, Rakeshkumar

    2016-01-01

    Tongue-tie or ankyloglossia is the congenital short thick lingual frenulum resulting in reduced mobility of the tongue. It limits the possibilities of the extension such as the protrusion and elevation of the tip of the tongue due to either the short of frenulum or genioglossus muscle or both. It can be observed at different ages with specific indications for treatment for each group and cause problems in the feeding, dental hygiene, speech, appearance, and self-esteem of affected patients. Although various degrees of the tongue-tie are mostly observed from the tip of tongue to the base of tongue, sometimes it may present unusually. The present article reports an unusual unique pattern of ankyloglossia where lingual frenum was exceptionally extended and merged with mandibular labium frenum. Reported case is one of the rarest types of ankyloglossia and emphasizes on its clinical implications, need for modifying diagnostic criteria, surgical management, and postoperative exercises. PMID:27994428

  15. Labial ankyloglossia: A rare case report.

    PubMed

    Bahadure, Rakesh Namdeo; Jain, Eesha; Singh, Parul; Pandey, Rameshkumar; Chuk, Rakeshkumar

    2016-01-01

    Tongue-tie or ankyloglossia is the congenital short thick lingual frenulum resulting in reduced mobility of the tongue. It limits the possibilities of the extension such as the protrusion and elevation of the tip of the tongue due to either the short of frenulum or genioglossus muscle or both. It can be observed at different ages with specific indications for treatment for each group and cause problems in the feeding, dental hygiene, speech, appearance, and self-esteem of affected patients. Although various degrees of the tongue-tie are mostly observed from the tip of tongue to the base of tongue, sometimes it may present unusually. The present article reports an unusual unique pattern of ankyloglossia where lingual frenum was exceptionally extended and merged with mandibular labium frenum. Reported case is one of the rarest types of ankyloglossia and emphasizes on its clinical implications, need for modifying diagnostic criteria, surgical management, and postoperative exercises.

  16. Determining the distance from the lingual frenum anterior attachment to the lower incisors' incisal edges.

    PubMed

    Mahboub, Farhang; Kimyai, Soodabeh; Molavi, Elahe

    2016-01-01

    Background. Occlusal rims are used to determine the jaw relationships in the transverse and vertical dimensions and estimate the inter-occlusal distance in edentulous patients. It is important to find ways to determine the height and shape of the occlusal rims correctly. This study was undertaken to determine the exact distance from the oral cavity floor to the incisal edges of mandibular incisors to serve as a guide for adjusting the height of the mandibular occlusal rim. Methods. Forty patients were selected and special trays were fabricated to prepare accurate stone casts on which the measurements were made at 0.01-mm accuracy. Two marks were placed on the casts at the incisal edges of mandibular incisors and at anterior attachment of lingual frenum. Then the distance between these two marks was determined on the vertical spindle of a surveyor using a digital Vernier measuring tool and recorded. Results. The results showed that the mean and standard deviation of the distances between the oral cavity floor and the incisal edges of lower incisors were 14.35 ± 1.68 mm, with a range of 10.2‒17.02 mm. The mean distances in males and females were 15.42 ± 0.97 and 13.28 ± 1.57 mm, respectively. T-test showed significant differences in this distance between males and females, with greater distances in males. Conclusion. The distance between the oral cavity floor and the incisal edges of mandibular incisors at anterior attachment of lingual frenum might be a proper criterion for the initial adjustment of occlusal rims.

  17. Determining the distance from the lingual frenum anterior attachment to the lower incisors’ incisal edges

    PubMed Central

    Mahboub, Farhang; Kimyai, Soodabeh; Molavi, Elahe

    2016-01-01

    Background. Occlusal rims are used to determine the jaw relationships in the transverse and vertical dimensions and estimate the inter-occlusal distance in edentulous patients. It is important to find ways to determine the height and shape of the occlusal rims correctly. This study was undertaken to determine the exact distance from the oral cavity floor to the incisal edges of mandibular incisors to serve as a guide for adjusting the height of the mandibular occlusal rim. Methods. Forty patients were selected and special trays were fabricated to prepare accurate stone casts on which the measurements were made at 0.01-mm accuracy. Two marks were placed on the casts at the incisal edges of mandibular incisors and at anterior attachment of lingual frenum. Then the distance between these two marks was determined on the vertical spindle of a surveyor using a digital Vernier measuring tool and recorded. Results. The results showed that the mean and standard deviation of the distances between the oral cavity floor and the incisal edges of lower incisors were 14.35 ± 1.68 mm, with a range of 10.2‒17.02 mm. The mean distances in males and females were 15.42 ± 0.97 and 13.28 ± 1.57 mm, respectively. T-test showed significant differences in this distance between males and females, with greater distances in males. Conclusion. The distance between the oral cavity floor and the incisal edges of mandibular incisors at anterior attachment of lingual frenum might be a proper criterion for the initial adjustment of occlusal rims. PMID:28096953

  18. Labial Adhesion with Acute Urinary Retention Secondary to Vaginitis

    PubMed Central

    Şentürk, Şenol; Üstüner, Pelin; Balık, Gülşah; Kağıtcı, Mehmet; Ural, Ülkü Mete; Şahin, Figen Kır

    2014-01-01

    Labial adhesion occurs most often in infants and girls and is usually associated with low estrogen levels. Labial adhesion in the reproductive age group is extremely rare due to abundance of estrogen. Herein we present a case of almost complete labial adhesion with acute urinary retention in a 21-year-old virgin woman secondary to a probable untreated severe vaginitis. PMID:25105038

  19. [Labial aging. Composition and therapeutic principles].

    PubMed

    Simon, E; Stricker, M; Duroure, F

    2002-10-01

    Labial ageing process combining relaxation, distension and ptosis is aggravated by underlying structure modification: dental and bony. If the inferior lip moves back and collapses, the superior lip will go down and widen. The authors analyse the different ageing process components (intrinsic and extrinsic) as well as therapeutic principles.

  20. Labial morphology: a 3-dimensional anthropometric study.

    PubMed

    Ferrario, Virgilio F; Rosati, Riccardo; Peretta, Redento; Dellavia, Claudia; Sforza, Chiarella

    2009-09-01

    To develop a noninvasive 3-dimensional method to evaluate labial morphology and to assess gender-related differences in healthy young adults. Dental and lip impressions of 11 men and 10 women aged 21 to 34 years, with sound, full, permanent dentition were obtained. The models were digitized and 3-dimensional virtual reproductions obtained. The labial thickness, vermilion area, and volume of the upper and lower lips were measured from the digital reconstructions. The male and female data were compared using Student's t test. The mean lip thickness was significantly larger (P = .02) in men (14.3 mm) than in women (12.3 mm). The lower lip was thicker than the upper lip. The vermilion width was larger in men (75 mm) than in women (70 mm), and no differences were found for vermilion height (10 mm). In the upper lip, the height/width ratio was significantly larger in women (14.1%) than in men (12.3%). The vermilion surface area was slightly larger in men than in women (upper lip area: women, 467 mm(2); men, 501 mm(2); lower lip area: women, 491 mm(2); men, 569 mm(2)). The labial volume was significantly larger in men (upper lip, 2,390 mm(3); lower lip, 2,902 mm(3)) than in women (upper lip, 1,743 mm(3); lower lip, 1,764 mm(3); P = .021). The upper/lower lip area and volume ratios were similar in the 2 genders. Overall, men had larger lips than women. The inferior lip height/width ratio was similar in both genders, and men had a relatively thinner upper lip than women.

  1. On the Interaction of Velar Fronting and Labial Harmony

    ERIC Educational Resources Information Center

    Dinnsen, Daniel A.; Green, Christopher R.; Morrisette, Michele L.; Gierut, Judith A.

    2011-01-01

    This article documents the typological occurrence and interactions of two seemingly independent error patterns, namely Velar Fronting and Labial Harmony, in a cross-sectional investigation of the sound systems of 235 children with phonological delays (ages 3;0 to 7;9). The results revealed that the occurrence of Labial Harmony depends on the…

  2. On the Interaction of Velar Fronting and Labial Harmony

    ERIC Educational Resources Information Center

    Dinnsen, Daniel A.; Green, Christopher R.; Morrisette, Michele L.; Gierut, Judith A.

    2011-01-01

    This article documents the typological occurrence and interactions of two seemingly independent error patterns, namely Velar Fronting and Labial Harmony, in a cross-sectional investigation of the sound systems of 235 children with phonological delays (ages 3;0 to 7;9). The results revealed that the occurrence of Labial Harmony depends on the…

  3. A Perceptual Correlate of the Labial-Coronal Effect

    ERIC Educational Resources Information Center

    Sato, Marc; Vallee, Nathalie; Schwartz, Jean-Luc; Rousset, Isabelle

    2007-01-01

    Purpose: Statistical studies conducted in various languages on both infants and adults have revealed an intersyllabic preference for initiating words with a labial consonant-vowel-coronal consonant sequence. Speech motor constraints have been proposed to explain this so-called "labial-coronal effect." This study was designed to test for a possible…

  4. Silks produced by insect labial glands

    PubMed Central

    Sutherland, Tara

    2008-01-01

    Insect silks are secreted from diverse gland types; this chapter deals with the silks produced by labial glands of Holometabola (insects with pupa in their life cycle). Labial silk glands are composed of a few tens or hundreds of large polyploid cells that secrete polymerizing proteins which are stored in the gland lumen as a semi-liquid gel. Polymerization is based on weak molecular interactions between repetitive amino acid motifs present in one or more silk proteins; cross-linking by disulfide bonds may be important in the silks spun under water. The mechanism of long-term storage of the silk dope inside the glands and its conversion into the silk fiber during spinning is not fully understood. The conversion occurs within seconds at ambient temperature and pressure, under minimal drawing force and in some cases under water. The silk filament is largely built of proteins called fibroins and in Lepidoptera and Trichoptera coated by glue-type proteins known as sericins. Silks often contain small amounts of additional proteins of poorly known function. The silk components controlling dope storage and filament formation seem to be conserved at the level of orders, while the nature of polymerizing motifs in the fibroins, which determine the physical properties of silk, differ at the level of family and even genus. Most silks are based on fibroin β-sheets interrupted with other structures such as α-helices but the silk proteins of certain sawflies have predominantly a collagen-like or polyglycine II arrangement and the silks of social Hymenoptera are formed from proteins in a coiled coil arrangement. PMID:19221523

  5. Comparative study of the labial gland secretion in termites (Isoptera).

    PubMed

    Sillam-Dussès, David; Krasulová, Jana; Vrkoslav, Vladimír; Pytelková, Jana; Cvačka, Josef; Kutalová, Kateřina; Bourguignon, Thomas; Miura, Toru; Šobotník, Jan

    2012-01-01

    Labial glands are present in all castes and developmental stages of all termite species. In workers, their secretion contains a food-marking pheromone and digestive enzymes, while soldier secretion plays a defensive role. However, these functions were studied only in a limited set of species, and do not allow drawing general conclusions. Hence, we have investigated the chemical composition of the labial gland extracts from soldiers and workers in 15 termite species belonging to 6 families using an integrative approach based on proteomic and small-molecule profiling. We confirmed the presence of hydroquinone and cellulase in the labial glands of workers, and we identified new toxic compounds in soldiers and workers of several species. Our results highlight the dual role of labial gland secretion, i.e. the defensive role in soldiers and workers of several termite species, and the digestive function in workers.

  6. Representing female desire within a labial framework of sexuality.

    PubMed

    Schiller, Britt-Marie

    2012-12-01

    Sexual experiences, rather than being neutral, are specifically male or female. Yet at present no conceptual framework exists for representing female sexual desire. This has resulted in frequent misrepresentations of female sexual experience. To correct this, a labial framework is proposed, not to replace or oppose a phallic framework, but to exist alongside it. The lips of the mouth and those of the genitals provide a felicitous doubling of sexuality and speech to represent female desire and sexual pleasure as labial. Phallic and labial rhythms are organized differently in sexual arousal and desire, since, as Simone de Beauvoir put it, "Man 'gets stiff,' but woman 'gets wet.'" The labial framework therefore represents female psychosexuality more in terms of "wetware" than of "hardware."

  7. Comparative Study of the Labial Gland Secretion in Termites (Isoptera)

    PubMed Central

    Sillam-Dussès, David; Krasulová, Jana; Vrkoslav, Vladimír; Pytelková, Jana; Cvačka, Josef; Kutalová, Kateřina; Bourguignon, Thomas; Miura, Toru; Šobotník, Jan

    2012-01-01

    Labial glands are present in all castes and developmental stages of all termite species. In workers, their secretion contains a food-marking pheromone and digestive enzymes, while soldier secretion plays a defensive role. However, these functions were studied only in a limited set of species, and do not allow drawing general conclusions. Hence, we have investigated the chemical composition of the labial gland extracts from soldiers and workers in 15 termite species belonging to 6 families using an integrative approach based on proteomic and small-molecule profiling. We confirmed the presence of hydroquinone and cellulase in the labial glands of workers, and we identified new toxic compounds in soldiers and workers of several species. Our results highlight the dual role of labial gland secretion, i.e. the defensive role in soldiers and workers of several termite species, and the digestive function in workers. PMID:23071569

  8. Labial swelling: a rare presentation of pubic bone tuberculosis.

    PubMed

    Shende, Prajakta; Gandhewar, Manisha; Gaikwad, Pradip; Nanaware, Sandip; Risbud Joshi, Prachi

    2016-09-14

    Tuberculosis (TB), being a global health problem, represents variedly. Its presentation as a labial swelling secondary to pubic bone TB has been reported rarely in literature. We report a case of pubic bone TB presenting as a labial swelling in a woman of reproductive age. Early diagnosis with fine needle aspiration cytology, acid-fast bacillus (AFB) staining, AFB culture and magnetic resonance imaging with early initiation of treatment resulted in a favourable outcome.

  9. A perceptual correlate of the labial-coronal effect.

    PubMed

    Sato, Marc; Vallée, Nathalie; Schwartz, Jean-Luc; Rousset, Isabelle

    2007-12-01

    Statistical studies conducted in various languages on both infants and adults have revealed an intersyllabic preference for initiating words with a labial consonant-vowel-coronal consonant sequence. Speech motor constraints have been proposed to explain this so-called labial-coronal effect. This study was designed to test for a possible perceptual correlate of the labial-coronal effect in French adults. The authors examined the perceptual stabilities of repeatedly presented disyllabic sequences, involving either a labial-vowel-coronal-vowel (LC) or a coronal-vowel-labial-vowel (CL) phonological structure. With this aim, they exploited the verbal transformation effect, which refers to the perceptual changes experienced while listening to a speech form cycled in rapid and continuous repetition. Two experiments were carried out, involving either voiced or unvoiced plosive consonants. In both experiments, a greater stability and attractiveness was observed for LC stimuli, which suggests that in a (...)LCLC(...) flow, the listener could more naturally provide a segmentation into LC chunks. This study demonstrates that the labial-coronal effect also occurs in the course of online speech processing. This result is interpreted in relation with theories assuming a link between perception and action in the human speech processing system.

  10. Stereophotogrammetric evaluation of tooth-induced labial protrusion.

    PubMed

    Rosati, Riccardo; De Menezes, Marcio; da Silva, Ana Maria Bettoni Rodrigues; Rossetti, Alberto; Lanza Attisano, Giuseppe C; Sforza, Chiarella

    2014-07-01

    To better manage dental treatment outcome, a previsualization of desired appearances can be used to understand patients' wishes. A deeper comprehension of labial modifications related to hard-tissue movements is advantageous. The purpose of the study was to evaluate tooth restoration-induced labial displacements in three dimensions. In a group of 20 healthy Caucasian individuals, simulations of vestibular translations of maxillary anterior crowns were obtained by placing an acrylic resin veneer on the labial surfaces of maxillary incisors and canines. Three-dimensional stereophotogrammetric acquisitions were made to evaluate soft-tissue changes induced by the simulations. Linear dislocation of selected landmarks and labial surfaces were quantified using dedicated software. All paired and two midline labial landmarks had significant displacements, ranging from 13% (Subnasale landmark) to 103% (left Cheilion landmark) of veneer thickness (2 mm thick). A significant positive correlation was obtained between the lower lip displacement and overjet values. The vestibular shift of maxillary incisors and canines affect both upper and lower vermilion areas, without involving cutaneous perilabial landmarks. © 2014 by the American College of Prosthodontists.

  11. Caterpillar labial saliva alters tomato plant gene expression.

    PubMed

    Musser, Richard O; Hum-Musser, Sue M; Lee, Henry K; DesRochers, Brittany L; Williams, Spencer A; Vogel, Heiko

    2012-11-01

    We examined the effects of Helicoverpa zea caterpillar labial saliva on tomato plant gene expression. Caterpillars with labial salivary glands (mock-ablated) and without (ablated) were fed on tomato plants for 24 hr; then, the leaf mRNA was analyzed with tomato microarrays. Analysis of the transcript profiles revealed 384 expressed sequence tags (ESTs) that were significantly altered due to herbivory compared to the non-wounded plants. The majority of the ESTs were quantitatively altered more so by mock-ablated caterpillars with labial salivary glands than ablated caterpillars. Particularly notable, ESTs encoding acid phosphatase, arginase, acidic endochitinase, dehydrin, polyphenol oxidase, protease inhibitors, and threonine deaminase were more highly stimulated by mock-ablated caterpillars than ablated caterpillars. In addition, tomato leaves were mechanically wounded with scissors and painted with labial salivary gland extract, autoclaved salivary gland extract, or water, and compared to non-wounded tomato plants. After 4 hr, these leaves were collected and a tomato microarray analysis of the mRNA revealed correlation of the gene expression of these leaves altered by mechanical wounding and painted with salivary gland extract to the gene expression of leaves fed on by mock-ablated caterpillars. We show that caterpillar labial saliva is an important component of herbivory that can alter plant gene expression.

  12. Reconstruction of Surgical Defects of the Labial Commissure.

    PubMed

    Otero-Rivas, M M; Alonso-Alonso, T; Pérez-Bustillo, A; Rodríguez-Prieto, M Á

    2015-11-01

    The main objective of oncologic dermatologic surgery is the complete excision of skin tumors. During reconstruction of the defect, we must attempt to preserve function and cosmetic appearance. At the labial commissure, fibers from the superior and inferior portions of the orbicularis oris muscle intersect and the vermillion inserts onto the modiolus, a complex, cone-shaped structure at the angle of the mouth. Surgical reconstruction of the labial commissure is challenging because of the need to preserve sphincter function and cosmetic symmetry. We present a number of cases of surgical defects at the labial commissure and describe the reconstruction techniques used. We also propose an algorithm to help determine the most suitable technique for different cases. Copyright © 2014 Elsevier España, S.L.U. y AEDV. All rights reserved.

  13. [Cutaneous and mucosal graft for labial defect after animal bite in children].

    PubMed

    Beltramina, G; Kadlub, N; Cassier, S; Constantinescu, G; Vazquez, M P; Picard, A

    2012-06-01

    Animal bite is frequently involved in children labial defect. The need for labial surgical repair is to restore anatomy and function. Local and regional flap is usually described for labial reconstructions. Few authors recommend mucosal and skin graft. In the present study, we described skin and mucosal graft for reconstruction of complex labial defect. This surgical technique can be applied in very young children with reasonable expectations of excellent functional and aesthetic outcome.

  14. Expectations and experience of labial reduction: a qualitative study.

    PubMed

    Bramwell, R; Morland, C; Garden, A S

    2007-12-01

    To understand women's reasons for undergoing labial reduction surgery, their expectations and experiences. A retrospective qualitative study. British National Health Service Hospital. Six women who had experienced surgery for labial reduction. Method Qualitative study using semi-structured interviews. Results relating to 'Normality and defect', 'Sex lives' and 'The process of accessing surgery' are presented in this study. The women had seen their presurgery genital appearance as 'defective' and sought a 'normal' genital appearance. They thought that their presurgery genital appearance impacted on their sex lives, but their expectations of the effects of surgery on their sex lives were not all fulfilled. Information about labial surgery came from both the popular media and the health services. An emphasis on, for example, physical discomfort rather than appearance may have been used to legitimise a request for surgery. The process of accessing surgery had exposed them to potentially conflicting messages about their genital appearance. Women presenting for labial reduction may have unrealistic expectations of surgery, but their perceptions and expectations are long-standing and seem to be based on strong cultural norms. The gynaecologist is also meeting those women who have already negotiated the referral process. As demand for this surgery appears to be increasing, further research is needed. These findings may add to the case for the potential value of specialist staff to provide psychosocial interventions within gynaecology services.

  15. On the interaction of velar fronting and labial harmony

    PubMed Central

    Dinnsen, Daniel A.; Green, Christopher R.; Morrisette, Michele L.; Gierut, Judith A.

    2012-01-01

    This article documents the typological occurrence and interactions of two seemingly independent error patterns, namely Velar Fronting and Labial Harmony, in a cross-sectional investigation of the sound systems of 235 children with phonological delays (ages 3;0 to 7;9). The results revealed that the occurrence of Labial Harmony depends on the occurrence of Velar Fronting, and that, when these processes co-occurred, all three predicted types of interactions were attested. A constrained version of Optimality Theory is put forward that offers a unified explanation for the implicational relationship between these error patterns and their observed interactions. The findings are compared with the results from other studies and are considered for their theoretical and clinical implications. PMID:21080824

  16. Glass embedded in labial mucosa for 20 years.

    PubMed

    Sumanth, K N; Boaz, Karen; Shetty, Naresh Y

    2008-01-01

    Foreign bodies may be deposited in the oral cavity either by traumatic injury or iatrogenically. Among the commonly encountered iatrogenic foreign bodies are restorative materials like amalgam, obturation materials, broken instruments, needles, etc. Few reports of glass pieces embedded in the soft tissues of the mouth have been published. We report a case where glass pieces had been lodged in the lower labial mucosa for 20 years, with consequent peripheral reactive bone formation.

  17. Labial and Vaginal Microbiology: Effects of Extended Panty Liner Use

    PubMed Central

    Enane, N. A.; Baldwin, S.; Berg, R. W.

    1997-01-01

    Objective: The goals of this study were 1) to better define the labial microflora and 2) to evaluate whether extended non-menstrual use of panty liners would increase genital carriage of undesirable bacteria and predispose to infection. Methods: Healthy female volunteers (224) were prospectively randomized into panty liner wear groups A (Always® deodorant) and B (Always® non-deodorant) and into a control group C (no panty liner wear) with instructions for non-menstrual ± menstrual use ≥5 h daily for 6 months. Selected aerobic bacteria were semiquantitatively cultured from the inner labial groove, the posterior fornix of the vagina, and the cervix pre-study and post-study. Used panty liners were quantitatively cultured, and vaginal secretions were examined by gas chromatography for fatty acid ratios as a measure of microbial flora shifts. Results: At the pre-study, labial microflora in this study population contained significantly higher frequencies of Staphylococcus, coliforms, other gram-negative rods, and enterococci, and a decreased frequency of Gardnerella vaginalis relative to the vaginal microflora. After 6 months use of panty liners the frequencies (and densities) of the selected microorganisms in these two sites had not changed compared to controls, and fatty acid analyses of vaginal secretions gave no evidence of shifts in the microbial flora. Conclusions: Frequencies of selected genital microflora were different for the labia compared to the vagina. No increased carriage of medically important species was detected for either site after 6 months of daily (average 7.8 h) panty liner use. PMID:18476146

  18. [Face replantation using labial artery for revascularization. Case report].

    PubMed

    de la Parra-Márquez, Miguel; Mondragón-González, Sergio; López-Palazuelos, Jaime; Naal-Mendoza, Norberto; Rangel-Flores, Jesús María

    2013-01-01

    antecedentes: la restauración cosmética y funcional de la cara luego de un traumatismo complejo es todo un reto para el cirujano plástico. En el ámbito internacional se han reportado pocos casos de reimplante facial. Objetivo: reportar el caso del primer reimplante parcial de cara con la utilización de la arteria labial como aporte vascular. Caso clínico: paciente masculino de siete años de edad. Ingresó al servicio de Cirugía Plástica en el mes de junio de 2011 por lesiones secundarias en la cara ocasionadas por la mordedura de un perro. A la exploración física se encontró avulsión de 75% del labio superior, 33% del labio inferior, incluida la comisura oral, y 75% de la mejilla izquierda. Los músculos avulsionados incluían: el orbicular de los labios, depresor del ángulo oral y depresor del labio inferior. El tiempo total de isquemia fue de ocho horas. La anastomosis término-terminal de la arteria coronaria labial se efectuó con nylon 11-0, posteriormente se escogió la vena con mejor retorno y la anastomosis se realizó con nylon 11-0. Se hizo miorrafía de los músculos mencionados con vicril 4-0, la sutura de la mucosa oral se realizó con vicril 5-0, y de la piel con nylon 5-0. Seis meses después de la cirugía, el resultado cosmético y funcional se consideró excelente, con restablecimiento total de la continencia labial y articulación completa de las palabras. Conclusiones: las amputaciones de cualquier componente facial deben ser inicialmente tratadas con reimplante. La arteria coronaria labial es una buena opción para revascularización, incluso en 25% del total de la cara (labios y mejilla).

  19. Dental and periodontal complications of labial and tongue piercing.

    PubMed

    Giuca, M R; Pasini, M; Nastasio, S; D' Ercole, S; Tripodi, D

    2012-01-01

    Piercing is the practice of puncturing some parts of the body to apply ornamental objects. The presence of oral and perioral piercings are a risk factor for many acute and chronic complications, such as chipping of the dental enamel, periodontal lesions and infection. The aim of this study is to assess the prevalence of lip and tongue piercing complications in the dental and periodontal tissues in a sample of young adults. Twenty-five adult patients were examined (test group: 11 males and 14 females with an average age of 23.4+/-3.6 years) who had had a minimum of one labial or tongue piercing for at least 1 year and were compared with 25 subjects (control group: 11 males - 44 percent, and 14 females - 56 percent) without any lingual or labial piercing. A questionnaire was compiled for each patient and a clinical examination was performed. The following parameters were examined by the same operator: abnormal toothwear, tooth chipping or cracking, clinical attachment loss (CAL), probing pocket depth (PD) and gingival recession (GR, classified by using Miller s classification). The data were analyzed using X2 or Fisher s exact test for small numbers and non-parametric Mann-Whitney or Kruskal-Wallis tests to examine for differences in continuity; the level of significance was p less than 0.05. According to the results found in the present study the prevalence of abnormal tooth wear and tooth chipping was higher in the subjects with labial or lingual piercing. Moreover, patients with tongue or labial piercing exhibited a higher GR in comparison to control subjects without any oral piercing. No differences were observed between the two groups as regards CAL and PD. A significant association between the duration of piercing and dental defects was found in the group of patients with piercings with greater prevalence of tooth and periodontal defects in the group of 13 subjects who had had the piercings for a period less than or equal to 4 years.

  20. The Labial-Coronal Effect Revisited: Japanese Adults Say Pata, but Hear Tapa

    ERIC Educational Resources Information Center

    Tsuji, Sho; Gomez, Nayeli Gonzalez; Medina, Victoria; Nazzi, Thierry; Mazuka, Reiko

    2012-01-01

    The labial-coronal effect has originally been described as a bias to initiate a word with a labial consonant-vowel-coronal consonant (LC) sequence. This bias has been explained with constraints on the human speech production system, and its perceptual correlates have motivated the suggestion of a perception-production link. However, previous…

  1. The Labial-Coronal Effect Revisited: Japanese Adults Say Pata, but Hear Tapa

    ERIC Educational Resources Information Center

    Tsuji, Sho; Gomez, Nayeli Gonzalez; Medina, Victoria; Nazzi, Thierry; Mazuka, Reiko

    2012-01-01

    The labial-coronal effect has originally been described as a bias to initiate a word with a labial consonant-vowel-coronal consonant (LC) sequence. This bias has been explained with constraints on the human speech production system, and its perceptual correlates have motivated the suggestion of a perception-production link. However, previous…

  2. Labial food challenge in children with food allergy.

    PubMed

    Rance, F; Dutau, G

    1997-02-01

    The current increase in the prevalence of food allergies appears to have several causes including better screening, improved diagnosis and changes in both the techniques used by food manufacturers and eating habits. Labial food challenge (LFC)is simple, rapid to perform and is associated with only low risks of systemic reaction. It is thus an appealing alternative to the oral food challenge (OFC) for pediatric use. We report a series of 202 LFC performed over two years in 142 children with food allergy suspected from the case history, positive skin prick tests and specific serum IgE assays: 156 LFC were positive; and 46 negative, followed by positive single-blind, placebo-controlled food challenges (SBPCFC). The foods provoking reactions were egg white (75 cases), peanut (60 cases), mustard (23 cases), cow's milk (13 cases), cod (8 cases), kiwi fruit, shrimp (4 cases each), chicken, peanut oil (3 cases each), hazel nuts (2 cases), and snails, apple, fennel, garlic, chilli peppers, pepper, and duck (1 case each). LFC positivity was mostly (89.7% of cases) manifested as a labial edema with contiguous urticaria. There were systemic reactions in 4.5% of cases: generalized urticaria, hoarseness and rapid-onset and generalized eczema. The 46 infants with negative LFC results had positive SBPCFC. The reactions were in 34 cases generalized urticaria, 10 cases asthma attacks, 2 cases early and generalized eczema, and in one case general anaphylactic shock. The sensitivity of the LFC was 77%. The LFC was easy to perform with children. Positive results indicate the presence of food allergy, but negative results require further investigations preferably double-blind, placebo-controlled food challenge (DBPCFC).

  3. Comparative Analysis and Systematic Mapping of the Labial Sensilla in the Nepomorpha (Heteroptera: Insecta)

    PubMed Central

    Brożek, Jolanta

    2013-01-01

    The present study provides new data concerning the morphology and distribution of the labial sensilla of 55 species of 12 nepomorphan families (Heteroptera: Nepomorpha) using the scanning electron microscope. On the labial tip, three morphologically distinct types of chemosensilla have been identified: two types of papillae sensilla and one type of peg-in-pit sensilla. Twenty-one morphologically distinct types of the mechanosensilla as well as two types of the trichoid sensilla (contact-chemoreceptive sensillum) have been identified on all labial segments in representatives of subfamilies. In Nepomorpha, morphological ground plan of the labial sensory structures is represented by an apical sensory field with 10–13 pairs of papillae sensilla and the peg-in-pit ones placed more laterally; numerous trichoid sensilla are placed on the IV segment; the chaetica sensilla are present and placed in groups or rows distributed along the labium near the labial groove on the dorsal side, and also several chaetica sensilla are unevenly scattered on the surface of that segment; the cupola and peg sensilla are numerous and evenly scattered on the fourth labial segment; the prioprerecptive sensilla, one pair is positioned on the dorsal side and on the fourth segment of the labium. The new apomorphical characters have been established for the labial sensilla in the Nepomorpha. PMID:23935421

  4. Erratum: Secondary reconstruction of vaginal stenosis using a posterior labial perforator based Falandry flap

    PubMed Central

    2016-01-01

    This erratum corrects article: “Secondary reconstruction of vaginal stenosis using a posterior labial perforator based Falandry flap”, The Pan African Medical Journal. 2015;21:185. doi:10.11604/pamj.2015.21.185.6559. PMID:27377057

  5. Attachment of swing-lock labial bar to an existing removable partial denture: a clinical report.

    PubMed

    Stevenson, R B; Wilson, W G; Caponigro, C V

    1988-10-01

    Although the swing-lock buccal or labial bar is often used as a periodontal splint for mobile teeth, it may also function as an orthodontic retainer to inhibit tooth migration of poorly aligned teeth. The labial bar may be added to an existing removable partial denture if there is sufficient bulk of acrylic resin in the denture bases to accommodate the hinge and latch.

  6. Success of treatment modalities for labial fusion: a retrospective evaluation of topical and surgical treatments.

    PubMed

    Mayoglou, Lazarus; Dulabon, Lori; Martin-Alguacil, Nieves; Pfaff, Donald; Schober, Justine

    2009-08-01

    Standard treatment for girls with labial fusion has included topical estrogen cream, manual separation, or surgery. Side effects may limit the use of topical estrogen. Betamethasone has recently shown efficacy at separating labial fusion. Local irritation and inflammation may be an initiator of labial fusion. No adverse effects of betamethasone treatment have been documented. Long-term side effects are unknown. This study compares therapies for conservative management of labial fusion for efficacy and focuses on the response rate, time to separation, recurrence, and side effects of treatment. A retrospective chart review. One hundred fifty-one prepubertal girls, mean age 3 years (range 0.25-8.75 years) diagnosed with labial fusion. To investigate the incidence of related symptoms, length of topical estrogen or betamethasone treatment, side effects, rate of successful separation, rates of recurrence, percentage requiring surgery, and postoperative outcomes in patients with labial adhesion who underwent treatment. Of 151 patients with labial adhesion, 11 (7.3%) presented with urinary frequency, 30 (19.9%) with urinary tract infections, 13 (8.6%) with vaginitis, and 19 (12.6%) with post-void dripping. When compared to patients treated with betamethasone (1.3 months), patients treated primarily with premarin took nearly twice as long (2.2 months) for resolution of their adhesions. Rates of recurrence were lower for patients receiving betamethasone therapy. Side effects for estrogen therapy included breast budding and vaginal bleeding, and for betamethasone, local irritation was reported. Some patients went on to surgery and experienced recurrence after surgery. Initial comparison of topical estrogen and betamethasone treatment of labial fusion suggests that betamethasone may separate fusion quicker with less recurrence and fewer side effects than topical estrogen therapy.

  7. Xwnt8 directly initiates expression of labial Hox genes.

    PubMed

    In der Rieden, Paul M J; Vilaspasa, Ferran Lloret; Durston, Antony J

    2010-01-01

    Hox transcription factors play an essential role in patterning the anteroposterior axis during embryogenesis and exhibit a complex array of spatial and temporal patterns of expression. Their earliest onset of expression in vertebrates is during gastrulation in a temporally collinear sequence in the presomitic/ventrolateral mesoderm, and it is not clear which upstream signal transduction events initiate this expression. Using Xenopus, we present evidence that Xwnt8 is necessary for initiation of this collinear sequence by activating Hox-1 expression in three Hox clusters: hoxd, hoxa, and hoxb. All three labial genes appear to be direct targets of canonical Wnt signaling through Tcf/Lef. In addition, Xwnt8 loss- and gain-of-function leads to indirect regulation of other Hox genes: Hoxb4, Hoxd4, Hoxa7, Hoxc6, and Hoxc8. These findings shed new light on the early role of Wnt8 as well as of a proposed WNT gradient in patterning the Xenopus central nervous system (Kiecker and Niehrs [2001] Development 128:4189-4201).

  8. Acoustic behavior of tuning slots of labial organ pipes.

    PubMed

    Rucz, Péter; Augusztinovicz, Fülöp; Angster, Judit; Preukschat, Tim; Miklós, András

    2014-05-01

    The effect of tuning slots on the sound characteristics of labial organ pipes is investigated in this paper by means of laboratory experiments. Besides changing the pitch of the pipe, the tuning slot also plays an important role in forming the timbre. The objectives of this contribution are to document the influence of tuning slots built with different geometries on the pipe sound and to validate the observed tendencies by means of reproducible experiments. It is found that the measured steady state sound spectra show unique characteristics, typical only for tuning slot organ pipes. By separately adjusting the geometrical parameters of the tuning slots on experimental pipes, the impact of each scaling parameter on the steady state spectrum is determined. It is shown that the scaling procedures used currently in organ building practice do not provide sufficient control over the sound characteristics, leaving the capabilities provided by the tuning slot unexploited. Subjective comparison made by organ builders of sound recordings of various setups confirms that the observed sound quality of tuning slot pipes is strongly dependent on the scaling of the slot.

  9. Clinical diagnosis of caliber-persistent labial artery of the lower lip.

    PubMed

    Lovas, J G; Goodday, R H

    1993-10-01

    Only 14 cases of caliber-persistent labial artery of the lower lip have been reported to date. Six of these were misdiagnosed and treated as squamous cell carcinoma, another as a mucocele. The correct diagnosis emerged only after the wedge resections were examined histopathologically. We report the first cases of caliber-persistent labial artery to be diagnosed clinically since the original description of the condition by Howell and Freeman in 1973. Our first case was a nonpulsatile hard, linear, "gooseneck lamp" submucosal nodule of the lower lip. On the basis of an initial misdiagnosis of sclerosing sialadenitis, a biopsy was attempted. Brisk pulsatile bleeding proved the lesion to be an artery, and the superficial location and large diameter of the vessel lead to the clinical diagnosis of caliber-persistent labial artery. The "gooseneck lamp" hardening is typical of Monckeberg's arteriosclerosis. The second case was a pulsatile blue linear submucosal nodule of the lower lip. The clinical diagnosis of caliber-persistent labial artery was confirmed when angiography showed the lesion to be an abnormally dilated labial artery. Both cases were successfully ligated with no complications at 16 and 10 months after surgery.

  10. Comparison of estrogen and betamethasone in the topical treatment of labial adhesions in prepubertal girls.

    PubMed

    Ertürk, Nazile

    2014-01-01

    To compare estrogen and betamethasone in the topical treatment of labial adhesions in prepubertal girls. In this retrospective study, we evaluated 39 girls with labial adhesions covering at least 50% of the vaginal opening. Of the total patients, 20 were treated with a topical estrogen preparation, while the remaining 19 patients were treated with a combination of betamethasone cream and petroleum ointment (Vaseline) for 3 to 9 weeks. Sixteen of 20 (80%) patients in the estrogen treatment group were treated successfully with topical estrogen cream only, and 17 of 19 (89.4%) patients in the second group were treated successfully with a combination of betamethasone cream and petroleum ointment. Two patients (2/20) in the estrogen treatment group underwent a surgical procedure for the manual separation of the labial adhesion. One patient (1/19) treated with betamethasone cream and petroleum ointment required a manual separation procedure. We observed a side effect of labial enlargement in 2 patients (10%) who were treated with estrogen only, while the only side effect of the betamethasone treatment was local irritation, which occurred in a single patient (5.2%). In addition, the success rate of the betamethasone treatment exceeded that of the topical estrogen (89.4% and 80%, respectively). Betamethasone cream with petroleum ointment is a safe and effective primary therapy for prepubertal labial adhesions.

  11. Electron microprobe analysis of human labial gland secretory granules in cystic fibrosis

    SciTech Connect

    Izutsu, K.; Johnson, D.; Schubert, M.; Wang, E.; Ramsey, B.; Tamarin, A.; Truelove, E.; Ensign, W.; Young, M.

    1985-06-01

    X-ray microanalysis of freeze-dried labial gland cryosections revealed that Na concentration was doubled and the Ca/S concentration ratio was decreased in secretory granules of labial glands from patients with cystic fibrosis (CF) when compared with glands from normal subjects. Other results suggested that the decrease in the Ca/S concentration ratio resulted from an increase in S concentration. These findings imply that mucous granules in labial saliva showed a CF-related increase in Na and S content, and such changes would be expected to affect the rheology of the mucus after exocytosis. In contrast with a previous study in human parotid glands, no evidence was found for CF-related changes in cytoplasmic or nuclear Na, K, and Ca concentrations. Significant elemental differences were found between secretory granules and nuclei and cytoplasm of control cells.

  12. Effect of age on immunoglobulin content and volume of human labial gland saliva.

    PubMed

    Smith, D J; Joshipura, K; Kent, R; Taubman, M A

    1992-12-01

    Stimulated lower labial (LLGF) and parotid salivary volumes and IgG, IgA, and IgM concentrations were measured in 264 subjects whose ages ranged from 17 to 76 years. A significant (p < 0.001) age-related decline in LLGF output was observed for subjects over this age range. Sixty-three percent of the subjects in the 18-20-year-old group (n = 46) secreted at least 10 microL of labial saliva in a 7-10-minute period, while approximately 70% of the subjects in the two oldest groups (61-70 and 71-76 years old) secreted less than 1 microL of LLGF during this time period (n = 64). No significant gender-based differences occurred in the volumes of labial saliva secreted. Stimulated parotid salivary flow showed no age-related trend in these subjects. Lower labial gland salivary IgA concentrations in an older population (mean age +/- SD = 55.6 yr +/- 1.3) were significantly lower (p < 0.025) than IgA concentrations in a younger population (20.7 yr +/- 0.8), when IgA was expressed as microgram/mL LLGF collected. Immunoglobulin A concentrations in parotid saliva and IgG and IgM concentrations in labial and parotid saliva were not significantly different when the two age populations were compared. These data suggest that the physiological and immunological potential of labial gland saliva may decrease with age.

  13. Labial cartilages in the smalltooth sandtiger shark, Odontaspis ferox (lamniformes: odontaspididae) and their significance to the phylogeny of lamniform sharks.

    PubMed

    Shimada, Kenshu; Rigsby, Cynthia K; Kim, Sun H

    2009-06-01

    Using computed tomography, we discovered labial cartilages (splanchnocranial components) in an enigmatic lamniform shark, Odontaspis ferox (smalltooth sandtiger). We demonstrate that the presence of labial cartilages is plesiomorphic in Lamniformes, affirming that their "reduction" cannot be used as a synapomorphy for the order. Rather, their loss occurred through lamniform phylogeny.

  14. Record base for an edentulous maxillary arch with severe undercuts in the labial aspect of the anterior residual ridge.

    PubMed

    Nishigawa, Goro; Maruo, Yukinori; Okamoto, Makoto; Minagi, Shogo

    2002-01-01

    A procedure is described for the fabrication of a record base for an edentulous maxillary arch with severe undercuts in the labial aspect of the anterior residual ridge. The record base is fabricated from autopolymerizing resin without soft lining materials and without blockout of the labial undercut of the stone cast.

  15. Regressive evolution of the arthropod tritocerebral segment linked to functional divergence of the Hox gene labial

    PubMed Central

    Pechmann, Matthias; Schwager, Evelyn E.; Turetzek, Natascha; Prpic, Nikola-Michael

    2015-01-01

    The intercalary segment is a limbless version of the tritocerebral segment and is present in the head of all insects, whereas other extant arthropods have retained limbs on their tritocerebral segment (e.g. the pedipalp limbs in spiders). The evolutionary origin of limb loss on the intercalary segment has puzzled zoologists for over a century. Here we show that an intercalary segment-like phenotype can be created in spiders by interfering with the function of the Hox gene labial. This links the origin of the intercalary segment to a functional change in labial. We show that in the spider Parasteatoda tepidariorum the labial gene has two functions: one function in head tissue maintenance that is conserved between spiders and insects, and a second function in pedipalp limb promotion and specification, which is only present in spiders. These results imply that labial was originally crucial for limb formation on the tritocerebral segment, but that it has lost this particular subfunction in the insect ancestor, resulting in limb loss on the intercalary segment. Such loss of a subfunction is a way to avoid adverse pleiotropic effects normally associated with mutations in developmental genes, and may thus be a common mechanism to accelerate regressive evolution. PMID:26311666

  16. Labial fusion: A rare cause of urinary retention in reproductive age woman and review of literature

    PubMed Central

    Erdoğdu, Emre; Demirel, Cem; Tahaoğlu, Ali Emre; Özdemir, Arzu

    2017-01-01

    Labial fusion usually affects prepubertal girls and postmenopausal women, it may rarely occurs in reproductive years in the absence of predisposing factors such as vulvar infections, dermatitis, trauma, female circumcision and lichen sclerosis. Should be considered in differential diagnosis in the differential diagnosis of urinary retention even if the patient doesn’t have history of sexual intercourse. PMID:28270959

  17. Interactions of the Tribolium Sex combs reduced and proboscipedia orthologs in embryonic labial development.

    PubMed Central

    DeCamillis, M A; Lewis, D L; Brown, S J; Beeman, R W; Denell, R E

    2001-01-01

    The role of Hox genes in the development of insect gnathal appendages has been examined in three insects: the fruitfly, Drosophila melanogaster; the milkweed bug, Oncopeltus fasciatus; and the red flour beetle, Tribolium castaneum. In each of these organisms, the identity of the labium depends on the homeotic genes Sex combs reduced (Scr) and proboscipedia (pb). Loss of pb function in each of the three insects results in homeotic transformation of the labial appendages to legs. In contrast, loss of Scr function yields a different transformation in each species. Interestingly, mutations in Cephalothorax (Cx), the Tribolium ortholog of Scr, transform the labial appendages to antennae, a result seen in the other insects only when both pb and Scr are removed. We show here that the Tribolium labial appendages also develop as antennae in double mutants. Further, we demonstrate that expression of the Tribolium proboscipedia ortholog maxillopedia (mxp) is greatly reduced or absent in the labium of Cx mutant larvae. Thus, in the wild-type labial segment, Cx function is required (directly or indirectly) for mxp transcription. A similar interaction between Scr and pb during Drosophila embryogenesis has been described recently. Thus, this regulatory paradigm appears to be conserved at least within the Holometabola. PMID:11779803

  18. Characterization of Neutral Lipase BT-1 Isolated from the Labial Gland of Bombus terrestris Males

    PubMed Central

    Brabcová, Jana; Prchalová, Darina; Demianová, Zuzana; Bučánková, Alena; Vogel, Heiko; Valterová, Irena; Pichová, Iva; Zarevúcka, Marie

    2013-01-01

    Background In addition to their general role in the hydrolysis of storage lipids, bumblebee lipases can participate in the biosynthesis of fatty acids that serve as precursors of pheromones used for sexual communication. Results We studied the temporal dynamics of lipolytic activity in crude extracts from the cephalic part of Bombus terrestris labial glands. Extracts from 3-day-old males displayed the highest lipolytic activity. The highest lipase gene expression level was observed in freshly emerged bumblebees, and both gene expression and lipase activity were lower in bumblebees older than 3 days. Lipase was purified from labial glands, further characterized and named as BT-1. The B. terrestris orthologue shares 88% sequence identity with B. impatiens lipase HA. The molecular weight of B. terrestris lipase BT-1 was approximately 30 kDa, the pH optimum was 8.3, and the temperature optimum was 50°C. Lipase BT-1 showed a notable preference for C8-C10 p-nitrophenyl esters, with the highest activity toward p-nitrophenyl caprylate (C8). The Michaelis constant (Km) and maximum reaction rate (Vmax) for p-nitrophenyl laurate hydrolysis were Km = 0.0011 mM and Vmax = 0.15 U/mg. Conclusion This is the first report describing neutral lipase from the labial gland of B. terrestris. Our findings help increase understanding of its possible function in the labial gland. PMID:24260337

  19. [Labial melanotic macule. Review of the literature. Report of a case].

    PubMed

    Salazar, N; Tinoco, P J; Segall, N

    1989-01-01

    A review of the literature is done concerning labial melanotic macule. Several aspects are studied such as definition, clinical significance and histopathology. A new case is added, located in the lower lip. Several observations are done and conclusions are drawn. Emphasis is given to the need of determining the etiology of the lesion.

  20. Betamethasone cream for the treatment of pre-pubertal labial adhesions.

    PubMed

    Myers, Jeremy B; Sorensen, Carsten M; Wisner, Benjamin P; Furness, Peter D; Passamaneck, Michelle; Koyle, Martin A

    2006-12-01

    We evaluated the efficacy of 0.05% betamethasone cream for the treatment of pre-pubertal labial adhesions. We retrospectively reviewed the records of 19 children with labial adhesions who were treated with betamethasone cream from 6/2001 to 3/2003. Children were treated with 1 to 3 courses of twice-daily 0.05% betamethasone cream for 4 to 6 weeks. Successful lysis of adhesions was assessed by clinical exam or parental phone contact and outcomes were defined as: (1) success--complete separation of labia, (2) partial success--greater than 75% separation, (3) progression to surgical lysis, and (4) lost to follow-up. Nineteen patients with an average age of 58 months (range 12 to 132 months) were treated. Four of the 19 patients had never been treated previously and 1 had been treated previously with surgical lysis of adhesions only. Fourteen of the 19 patients had been previously treated with conjugated estrogen (Premarin) cream. Two of these fourteen patients had also undergone surgical lysis of adhesions. Severity of adhesions ranged from 33% to 99% labial closure. Betamethasone cream was successful in treating 13/19 (68%) pre-pubertal labial adhesions. Eleven (85%) of these 13 patients had complete resolution of labial adhesions with 1 course of treatment, 1 (7.5%) had resolution with 2 courses of treatment and 1 (7.5%) had resolution with 3 courses of treatment. One patient had a partial success with 3 courses of betamethasone cream. Two (11%) patients underwent surgical lysis of adhesion after 1 and 2 courses of betamethasone cream respectively. Three (16%) patients were lost to follow-up. Average follow-up was 7 months (range 1-24 months). No adverse outcomes or untoward effects were noted in any of the patients treated. Betamethasone 0.05% cream appears to be a safe and effective treatment of pre-pubertal labial adhesions as primary therapy or in patients that have failed previous therapies and it may avoid the undesirable side effects of breast budding and

  1. Phylogenetic signals from Nepomorpha (Insecta: Hemiptera: Heteroptera) mouthparts: stylets bundle, sense organs, and labial segments.

    PubMed

    Brożek, Jolanta

    2014-01-01

    The present study is a cladistic analysis of morphological characters focusing on the file of the mandible, the apices of the maxillae, the rupturing device on the maxillae, the internal structures of the mouthparts, and the external morphology of the labial segments as well as the distribution of labial sensilla in true water bugs (Hemiptera: Heteroptera, infraorder Nepomorpha). The study is based on data referring to sixty-two species representing all nepomorphan families (Heteroptera), together with one outgroup species representing the infraorders Gerromorpha (Mesoveliidae). The morphological data matrix consists of forty-eight characters. The present hypothesis supports the monophyly of the Nepomorpha and the monophyly of all families. The new modification in the systematic classification has been proposed: ((Nepidae + Belostomatidae), (Diaprepocoridae + Corixidae + Micronectidae), (Ochteridae + Gelastocoridae), Aphelocheiridae, Potamocoridae, Naucoridae, Notonectidae, and (Pleidae + Helotrephidae)).

  2. Recurrent Labial Herpes Simplex in Pediatric Dentistry: Low-level Laser Therapy as a Treatment Option.

    PubMed

    Stona, Priscila; da Silva Viana, Elizabete; Dos Santos Pires, Leandro; Blessmann Weber, João Batista; Floriani Kramer, Paulo

    2014-05-01

    Recurrent labial herpes simplex is a pathology of viral origin that is frequently observed in children. The signs and symptoms are uncomfortable and, in many cases, the efficacy of treatment is unproven. However, several studies have demonstrated good results from the use of low-level laser therapy (LLLT), primarily due to acceleration of the healing process and pain relief, which make it a promising resource for use with this pathology. This paper describes a clinical case of a 7-year-old patient affected by this pathology and the therapeutic resolution proposed. How to cite this article: Stona P, da Silva Viana E, dos Santos Pires L, Weber JBB, Kramer PF. Recurrent Labial Herpes Simplex in Pediatric Dentistry: Low-level Laser Therapy as a Treatment Option. Int J Clin Pediatr Dent 2014;7(2):140-143.

  3. Comparison of speech performance in labial and lingual orthodontic patients: A prospective study

    PubMed Central

    Rai, Ambesh Kumar; Rozario, Joe E.; Ganeshkar, Sanjay V.

    2014-01-01

    Background: The intensity and duration of speech difficulty inherently associated with lingual therapy is a significant issue of concern in orthodontics. This study was designed to evaluate and to compare the duration of changes in speech between labial and lingual orthodontics. Materials and Methods: A prospective longitudinal clinical study was designed to assess speech of 24 patients undergoing labial or lingual orthodontic treatment. An objective spectrographic evaluation of/s/sound was done using software PRAAT version 5.0.47, a semiobjective auditive evaluation of articulation was done by four speech pathologists and a subjective assessment of speech was done by four laypersons. The tests were performed before (T1), within 24 h (T2), after 1 week (T3) and after 1 month (T4) of the start of therapy. The Mann-Whitney U-test for independent samples was used to assess the significance difference between the labial and lingual appliances. A speech alteration with P < 0.05 was considered to be significant. Results: The objective method showed a significant difference to be present between the two groups for the/s/sound in the middle position (P < 0.001) at T3. The semiobjective assessment showed worst speech performance in the lingual group to be present at T3 for vowels and blends (P < 0.01) and at T3 and T4 for alveolar and palatal consonants (P < 0.01). The subjective assessment also showed a significant difference between the two groups at T3 (P < 0.01) and T4 (P < 0.05). Conclusion: Both appliance systems caused a comparable speech difficulty immediately after bonding (T2). Although the speech recovered within a week in the labial group (T3), the lingual group continued to experience discomfort even after a month (T4). PMID:25540661

  4. A randomized clinical trial comparing mandibular incisor proclination produced by fixed labial appliances and clear aligners.

    PubMed

    Hennessy, Joe; Garvey, Thérèse; Al-Awadhi, Ebrahim A

    2016-09-01

    To compare the mandibular incisor proclination produced by fixed labial appliances and third generation clear aligners. Patients underwent a course of orthodontic treatment using either fixed labial appliances or clear aligners (Invisalign). Mandibular incisor proclination was measured by comparing pretreatment and near-end treatment lateral cephalograms. Eligibility criteria included adult patients with mild mandibular incisor crowding (<4 mm) and Class I skeletal bases (ANB, 1-4°). The main outcome was the cephalometric change in mandibular incisor inclination to the mandibular plane at the end of treatment. Eligible patients picking a sealed opaque envelope, which indicated their group allocation, was used to achieve randomization. Data was analyzed using a Welch two-sample t-test. Forty-four patients (mean age, 26.4 ± 7.7 years) were randomized in a 1:1 ratio to either the fixed labial appliance or the clear aligner group. Baseline characteristics were similar for both groups: Fixed appliance mean crowding was 2.1 ± 1.3 mm vs clear aligner mean crowding, 2.5 ± 1.3 mm; pretreatment mean mandibular incisor inclination for the fixed appliance group was 90.8 ± 5.4° vs 91.6 ± 6.4° for the clear aligner group. Fixed appliances produced 5.3 ± 4.3° of mandibular incisor proclination. Clear aligners proclined the mandibular incisors by 3.4 ± 3.2°. The difference between the two groups was not statistically significant (P > .05). There was no difference in the amount of mandibular incisor proclination produced by clear aligners and fixed labial appliances in mild crowding cases.

  5. Clinical characteristics of well women seeking labial reduction surgery: a prospective study.

    PubMed

    Crouch, N S; Deans, R; Michala, L; Liao, L-M; Creighton, S M

    2011-11-01

    To assess clinical characteristics and expectations in well women requesting elective labial reduction surgery. Prospective study of women attending an outpatient gynaecology clinic. General gynaecology clinic at a Central London teaching hospital. Women requesting labial reduction surgery and referred by their general practitioner. The labia minora width and length were measured for all participants for comparison with published normal values. The presenting complaint was recorded, along with demographic details, expectations of surgery and sources of information regarding appearance of the labia. Labial measurements, reported symptoms and expectations of surgery. The labia of all participants were within normal published limits, with a mean (SD) of 26.9 (12.8) mm (right labia), and 24.8 (13.1) mm (left labia). The majority of complaints were regarding appearance or discomfort. Expectations were to alter the appearance with surgery. All women seeking surgery had normal-sized labia minora. Clear guidance is needed for clinicians on how best to care for the worried well woman seeking surgery. © 2011 The Authors BJOG An International Journal of Obstetrics and Gynaecology © 2011 RCOG.

  6. Reconstruction of intraoral defects with superior labial artery musculo-mucosal flap: a preliminary clinical study.

    PubMed

    Güven, Erdem; Uğurlu, Alper Mete; Başaran, Karaca; Basat, Salih Onur; Yiğit, Bariş; Hafiz, Günter; Kuvat, Samet Vasfi

    2010-01-01

    In this article, we present the use of the superior labial artery musculo-mucosal (SLAMM) flap for intraoral reconstruction. The study included five patients (2 females, 3 males; mean age 36 years; range 11 to 56 years) who consulted at our clinic between October 2008 and January 2010. Five oral defects were reconstructed with the SLAMM flap. Three patients underwent reconstruction with SLAMM flap following oncologic resection. The other two patients had traumatic defects in the oral cavity which necessitated flap application. First, the distal end of the flap was incised and the superior labial artery was identified after dissection. After ligation of the artery, the mucosa, submucosa and the cuff of orbicularis oris muscle were elevated. The dissection was extended laterally and anteriorly, depending on the necessary flap size. None of the patients had partial or total flap necrosis. During the follow-up period, contracture developed in only one patient. Successful reconstruction was observed in all patients. The superior labial artery musculo-mucosal flap is a simple and feasible technique which can be used for reconstruction of intraoral defects.

  7. A stingless bee uses labial gland secretions for scent trail communication ( Trigona recursa Smith 1863).

    PubMed

    Jarau, S; Hrncir, M; Zucchi, R; Barth, F G

    2004-03-01

    The pheromones used by several species of stingless bees for scent trail communication are generally assumed to be produced by the mandibular glands. Here we present strong evidence that in Trigona recursa these pheromones originate from the labial glands, which are well developed in the heads of foragers. Analysis of the behavior involved in scent marking shows that a bee extends her proboscis and rubs it over the substrate. A single scent marking event lasts for 0.59+/-0.21 s while the bee runs a stretch of 1.04+/-0.37 cm on a leaf. According to choice experiments the bees are attracted by a feeder baited with labial gland extract (84.2+/-6% of the bees choose this feeder) but repelled from a feeder baited with mandibular gland extract (only 27.5+/-13.1% of the bees choose this feeder). They do not discriminate between two clean feeders (49.6+/-3% of the bees at a feeder). 87+/-5.1% of bees already feeding leave the feeder after the application of mandibular gland extract whereas only 6.2+/-4.9% and 2.6+/-4% do so when labial gland extract or pure solvent was applied.

  8. Pyosalpinx as a sequela of labial fusion in a post-menopausal woman: a case report

    PubMed Central

    2011-01-01

    Introduction Complete labia fusion is a rare clinical entity in post-menopausal women. The most common complications of this presentation are infections of the urinary tract and retention of urine in the vagina. We present the case of a post-menopausal woman with adnexal mass and abdominal pain due to fusion of the labia majora. To the best of our knowledge this is the first report in the literature of this complication. Case presentation A 78-year-old Caucasian woman was admitted to our hospital due to abdominal pain and urination difficulty, along with fever and leucocytosis. On examination the labial majora were fused. Computed tomography of the abdomen revealed a cystic formation in the anatomical area of the right adnexa. Our patient had developed a pyosalpinx as a Sequela of labial fusion. At laparoscopy the right pyosalpinx was identified and resected, whereas the labia majora were reconstructed via dissection and separation. Conclusions Labial fusion is a rare clinical entity in post-menopausal women and can have serious and unexpected complications. Though this presentation is rare, a clinical examination must be performed in detail in order to gain valuable information for an accurate diagnosis. Post-operational instruction must be given to patients in order to prevent the re-occurrence of the fusion and its complications. PMID:22054217

  9. The applications of diode and Er:YAG lasers in labial frenectomy in infant patients.

    PubMed

    Gontijo, Isa; Navarro, Ricardo S; Haypek, Patrícia; Ciamponi, Ana Lídia; Haddad, Ana Estela

    2005-01-01

    This paper describes a clinical case of labial frenectomy using different high power lasers: diode (810 nm) and Er:YAG (2940 nm). Considerations are made about specific indications, surgery techniques, and advantages of labial frenectomy using these laser wavelengths. The diode laser has high absorbance by pigmented tissues with hemoglobin, melanin, and collagen chromophores. For this reason, this wavelength is well indicated for surgery in soft tissue (vaporization, incision, coagulation, hemostasis). It is not properly absorbed, however, and should never be used in contact with hard tissues (bone). The Er:YAG laser has high absorbance to water and mineral apatite, making this wavelength useful and safe for the ablation of hard tissues. In the labial frenectomy clinical procedure, a combined technique is suggested: using the diode laser in soft tissues and the Er:YAG laser in periosteal bone tissues and for removal of final collagen fibers. It is important for the professional to understand the physical characteristics of the different laser wavelengths and their interaction with biological tissues to assure that they are used in a safe way, and that the benefits of this technology can be provided to infant patients.

  10. Urethrolysis with Martius labial fat pad graft for iatrogenic bladder outlet obstruction.

    PubMed

    Carey, Jeffrey M; Chon, Joanna K; Leach, Gary E

    2003-04-01

    This article evaluates treatment outcomes of urethrolysis with the Martius labial fat pad graft for patients with outlet obstruction after incontinence surgery. A total of 23 women were diagnosed with iatrogenic bladder outlet obstruction by urinary retention, urodynamic criteria, physical examination findings, and/or temporal relation of voiding dysfunction to anti-incontinence surgery. The urodynamic definition of female outlet obstruction was a maximum flow rate <12 mL/sec and a detrusor pressure at maximum flow >20 cm of water. Surgical treatment consisted of urethrolysis with complete circumferential urethral mobilization. A Martius labial fat pad graft was used to circumferentially wrap the urethra. No concurrent resuspension procedures were performed. Procedure efficacy was determined by retrospective review and phone interview. Mean patient age was 55 years (range, 37 to 85 years). Mean postoperative follow-up time was 15 months (maximum, 44 months). All patients related voiding dysfunction symptoms to their anti-incontinence surgery. In all, 17 of 23 (74%) patients had preoperative urinary retention requiring catheterization, and 63% of patients met urodynamic criteria for obstruction. After urethrolysis with a Martius labial fat pad graft, 20 of 23 (87%) patients had complete resolution of their obstruction; 3 patients required persistent catheterization. Postoperative stress incontinence was reported by 6 of 23 (13%) patients. Urodynamically documented detrusor instability occurred in 6 of 23 (26%) patients with de novo detrusor instability occurring in 3 of 15 (20%) patients.

  11. Changes in the oral environment after placement of lingual and labial orthodontic appliances.

    PubMed

    Lombardo, Luca; Ortan, Yildiz Öztürk; Gorgun, Özge; Panza, Chiara; Scuzzo, Giuseppe; Siciliani, Giuseppe

    2013-09-11

    This study compared the oral hygiene and caries risk of patients treated with labial and lingual orthodontic appliances throughout a prospective evaluation of the status of the oral environment before and after bracket placement. A total of 20 orthodontic patients aged 19 to 23 years were included in the study and were divided into two groups: 10 patients wore Roth labial appliance (American Orthodontics, Sheboygan, WI, USA) and 10 patients wore STb lingual appliance (Ormco Corporation, Glendora, CA, USA). Plaque index (PI), gingival bleeding index (GBI), salivary flow rate, saliva buffer capacity, salivary pH, and Streptococcus mutans and Lactobacillus counts in saliva were determined at three time points: before orthodontic appliance placement (T0), 4 weeks after bonding (T1), and 8 weeks after bonding (T2). After appliance placement, all patients were periodically educated to the oral hygiene procedures. Wilcoxon rank and Mann-Whitney U tests were used to determine intragroup and intergroup differences as regards qualitative data. To compare quantitative data between the groups, chi-square and Fisher's exact tests were undertaken, while intragroup differences were tested with McNemar test. The level of statistical significance was set at p<0.05. Statistical analysis of the data obtained revealed a statistically significant difference between the data of T0 and T1 and the data of T0 and T2 of the PI scores and between T0 and T2 of the GBI scores in the group treated with the lingual appliance. The GBI value increased significantly between T0 and T1 but decreased significantly between T1 and T2 (p<0.01) in the group treated with labial appliance. S. mutans counts increased significantly between T0 and T2 in the saliva samples of patients treated with lingual appliance. No statistically significant differences were found between S. mutans and Lactobacillus counts at the three terms of saliva collection in patients treated with labial appliance. No statistically

  12. Associations between xerostomia, histopathological alterations, and autonomic innervation of labial salivary glands in men in late midlife.

    PubMed

    Sørensen, Christiane Elisabeth; Larsen, Jytte Overgaard; Reibel, Jesper; Lauritzen, Martin; Mortensen, Erik Lykke; Osler, Merete; Pedersen, Anne Marie Lynge

    2014-09-01

    One aim of the present study was to investigate whether symptoms of oral dryness (xerostomia) during daytime, assessed in a study group of middle-aged male positive and negative outliers in cognition scores, were associated with age-related degenerative changes in human labial salivary glands and with quantitative measures of the glandular autonomic innervation. Another aim was to study the relation between the autonomic innervation and loss of secretory acinar cells in these glands. Labial salivary gland biopsies were taken from the lower lip from 190 men, born in 1953 and members of the Danish Metropolit birth cohort, who were examined for age-related changes in cognitive function and dental health as part of the Copenhagen University Center for Healthy Aging clinical neuroscience project. The glands were routinely processed and semi-quantitatively analyzed for inflammation, acinar atrophy, fibrosis, and adipocyte infiltration. Sections of labial salivary gland tissue were stained with the panneuronal marker PGP 9.5. In a subsample of 51 participants, the autonomic innervation of the glands was analyzed quantitatively by use of stereology. Labial salivary gland tissue samples from 33% of all participants displayed moderate to severe acinar atrophy and fibrosis (31%). Xerostomia was not significantly associated with structural changes of labial salivary glands, but in the subsample it was inversely related to the total nerve length in the glandular connective tissue. Acinar atrophy and fibrosis were negatively correlated with the parenchymal innervation and positively related to diffuse inflammation. The results from the present study indicate that aspects of the autonomic innervation of labial salivary glands may play a role in the occurrence of xerostomia which in the present study group was not significantly associated with degenerative changes in these glands. The findings further indicate that the integrity of labial salivary gland acini is related to the

  13. A Labially Positioned Mesiodens and Its Repositioning as a Missing Central Incisor

    PubMed Central

    Ephraim, Rena; Dilna, N C; Sreedevi, S; Shubha, M

    2014-01-01

    Hyperdontia is an increased number of teeth within the dental arches. This is of particular interest to pediatric dentists who commonly make the initial diagnosis. Most often a large portion of these teeth is completely embedded or impacted within the jaws and can be viewed only radiographically. Hyperdontia can occur on virtually every tooth-bearing surface. However, the most frequent is the mesiodens, in the anterior maxillary region. Anterior maxillary teeth are one of the most important features contributing to aesthetics of an individual. Missing anterior teeth can cause undue psychological stress in children, during their growing years. Most of the literature available show that the mesiodens are situated on the palatal aspect of the permanent incisors. Their treatment frequently involves an early recognition, extraction through a traditional palatal technique and guiding the associated permanent tooth to its original position. The purpose of this article is to enlighten the clinician of the need of deviating from the traditional approach of early extraction in particular situations and to conserve the mesiodens if favorable as an alternative treatment to a malformed permanent tooth, which may fail to erupt. This report describes a successful multidisciplinary approach to treatment of a unerrupted, labially placed mesiodens in conjunction with a dilacerated and impacted permanent tooth, in a child with a missing left central incisor. Treatment consisted of localizing and confirming the placement of the mesiodens to be labial, surgically exposing the crown of the mesiodens through a labial surgical approach, orthodontically guiding it to the position of the missing central incisor, extracting the malformed permanent incisor, and restoring the mesiodens to the required anatomy with composites, to establish aesthetics and function of the affected region. PMID:25395807

  14. A labially positioned mesiodens and its repositioning as a missing central incisor.

    PubMed

    Ephraim, Rena; Dilna, N C; Sreedevi, S; Shubha, M

    2014-09-01

    Hyperdontia is an increased number of teeth within the dental arches. This is of particular interest to pediatric dentists who commonly make the initial diagnosis. Most often a large portion of these teeth is completely embedded or impacted within the jaws and can be viewed only radiographically. Hyperdontia can occur on virtually every tooth-bearing surface. However, the most frequent is the mesiodens, in the anterior maxillary region. Anterior maxillary teeth are one of the most important features contributing to aesthetics of an individual. Missing anterior teeth can cause undue psychological stress in children, during their growing years. Most of the literature available show that the mesiodens are situated on the palatal aspect of the permanent incisors. Their treatment frequently involves an early recognition, extraction through a traditional palatal technique and guiding the associated permanent tooth to its original position. The purpose of this article is to enlighten the clinician of the need of deviating from the traditional approach of early extraction in particular situations and to conserve the mesiodens if favorable as an alternative treatment to a malformed permanent tooth, which may fail to erupt. This report describes a successful multidisciplinary approach to treatment of a unerrupted, labially placed mesiodens in conjunction with a dilacerated and impacted permanent tooth, in a child with a missing left central incisor. Treatment consisted of localizing and confirming the placement of the mesiodens to be labial, surgically exposing the crown of the mesiodens through a labial surgical approach, orthodontically guiding it to the position of the missing central incisor, extracting the malformed permanent incisor, and restoring the mesiodens to the required anatomy with composites, to establish aesthetics and function of the affected region.

  15. Effects of labial adhesion on maxillary arch dimensions and nasolabial esthetics in cleft lip and palate: a systematic review.

    PubMed

    Thierens, Lam; Brusselaers, N; De Roo, Nmc; De Pauw, Gam

    2017-10-01

    Labial adhesion is a preliminary surgical lip approximation used in the early management of unilateral and bilateral cleft lip and palate. Our objective was to evaluate its effects on the maxillary arch dimensions and nasolabial esthetics by means of a systematic review. The literature search (1955-2016) was based on MEDLINE via PubMed, Web of Science, EMBASE, and the Cochrane Library. Studies with labial adhesion as a single preliminary step for definitive lip closure, in combination with nasoalveolar molding or in combination with infant orthopedics were considered eligible. Fifteen articles were identified (1978-2015), including 587 patients who underwent labial adhesion. Reduction in alveolar cleft width was between 60.9% and 100% in unilateral cases and between 47.5% and 100% in bilateral cases. Reduction in palatal cleft width was between 28.4% and 59.8% in unilateral cases and between 37.5% and 50.5% in bilateral cases. No conclusive results could be drawn about the effect on nasolabial esthetics. This systematic review comprises the available literature of the last 50 years about labial adhesion. It showed reduction of alveolar and palatal cleft width after a treatment with labial adhesion with or without infant orthopedics. The treatment effect on nasolabial esthetics, especially in the long term, remains unclear. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  16. Identification of candidate downstream genes for the homeodomain transcription factor Labial in Drosophila through oligonucleotide-array transcript imaging

    PubMed Central

    Leemans, Ronny; Loop, Thomas; Egger, Boris; He, Haiqiong; Kammermeier, Lars; Hartmann, Beate; Certa, Ullrich; Reichert, Heinrich; Hirth, Frank

    2001-01-01

    Background: Homeotic genes are key developmental regulators that are highly conserved throughout evolution. Their encoded homeoproteins function as transcription factors to control a wide range of developmental processes. Although much is known about homeodomain-DNA interactions, only a small number of genes acting downstream of homeoproteins have been identified. Here we use a functional genomic approach to identify candidate target genes of the Drosophila homeodomain transcription factor Labial. Results: High-density oligonucleotide arrays with probe sets representing 1,513 identified and sequenced genes were used to analyze differential gene expression following labial overexpression in Drosophila embryos. We find significant expression level changes for 96 genes belonging to all functional classes represented on the array. In accordance with our experimental procedure, we expect that these genes are either direct or indirect targets of labial gene action. Among these genes, 48 were upregulated and 48 were downregulated following labial overexpression. This corresponds to 6.3% of the genes represented on the array. For a selection of these genes, we show that the data obtained with the oligonucleotide arrays are consistent with data obtained using quantitative RT-PCR. Conclusions: Our results identify a number of novel candidate downstream target genes for Labial, suggesting that this homeoprotein differentially regulates a limited and distinct set of embryonically expressed Drosophila genes. PMID:11387036

  17. Treatment of pseudo Class III malocclusion by modified Hawleys appliance with inverted labial bow.

    PubMed

    Negi, K S; Sharma, K R

    2011-01-01

    Pseudo Class III malocclusion is characterized by an anterior crossbite with functional forward mandibular displacement. Various appliances have been devised for early treatment of a pseudo Class III. The aim of this article is to highlight the method of construction and use a simple removable appliance termed as "Modified Hawleys appliance with inverted labial bow" to treat psuedo class III malocclusion in the mixed dentition period. It also emphasizes the importance of differentiating between true Class III and pseudo Class III. This appliance in this type of malocclusion enabled the correction of a dental malocclusion in a few months and therapeutic stability of a mesially positioned mandible encouraging favorable skeletal growth.

  18. Accuracy and reliability of cone beam computed tomographic measurements of the bone labial and palatal to the maxillary anterior teeth.

    PubMed

    Behnia, Hossein; Motamedian, Saeed Reza; Kiani, Mohammad Taghi; Morad, Golnaz; Khojasteh, Arash

    2015-01-01

    The aim of this study was to measure the thickness of bone labial and palatal to maxillary anterior teeth on cone beam computed tomographic (CBCT) images and to compare these measurements with direct clinical measurements to determine the reliability and accuracy of CBCT. Eighteen healthy subjects were randomly selected from among candidates for immediate implant placement in the anterior maxilla. After extraction, labial bone thickness was measured at 1, 4, and 8 mm from the bone crest. Palatal bone thickness was also measured at 1 and 4 mm from the bone crest. The same measurements were performed on presurgical CBCT images. The CBCT measurements were compared to the direct measurements, and their accuracy and reliability were assessed by Pearson correlation coefficients and intraclass correlation coefficients, respectively. The mean width of labial bone was 0.50 ± 0.32 mm and 0.76 ± 0.37 mm for direct and CBCT measurements, respectively. Average thickness of the palatal bone was 1.16 ± 0.53 mm and 1.41 ± 0.51 mm for direct and CBCT measurements, respectively. The mean absolute error and mean relative error of CBCT measurements compared to direct measurements were 0.28 ± 0.29 mm and 0.60 ± 0.84 mm, respectively. The Pearson correlation between CBCT and direct measurements was 0.795 (P < .001) and the intraclass correlation coefficient between direct and CBCT measurements was 0.840. The correlation between the measurement series increased significantly when the measured bone was more than 1 mm thick. CBCT measurements of labial bone mostly overestimated bone thickness. CBCT has relatively good accuracy and reliability for measurement of labial bone thickness when the alveolar bone is thicker than 1 mm. However, most subjects have labial bone thinner than 1 mm; therefore, CBCT could result in large errors in many patients.

  19. Comparison of two different labial salivary gland biopsy incision techniques: A randomized clinical trial

    PubMed Central

    Ati775 i?kler, Mert; Ergun, Sertan; Ofluo?lu, Duygu; Tanyeri775 i?, Hakk?

    2013-01-01

    Objectives: To compare the reliability of two different labial salivary gland biopsy (LSGB) incision techniques (vertical versus horizontal incision techniques) and to report the related complications and discomfort. Study Design: 163 patients who underwent LSGB were included in this study. Patients were randomly divided as vertical incision group (n=81) and horizontal incision group (n=82). Demographic and clinical information of each patient were recorded. A questionnaire was prepared and applied together with Visual Analog Scale (VAS) on the subjects verbally at the 7th day, postoperatively. Intraoperative, short- term and delayed complications were evaluated. Results: The mean age of patients (117 female, 46 male) was 47.3 years (range 19-79 years). Vertical incision technique was associated with less pain (p<0.001), less swelling (p<0.05), less scar formation (p<0.05) and less difficulty in eating (p<0.05) when compared with horizontal incision technique. No statistically significant differences were observed between the 2 groups in terms of hematoma, parasthesia and speech difficulty (p>0.05). Additionally, two subjects in the horizontal incision group revealed permanent paresthesia during the follow-up period of two years. Conclusions: This prospective study demonstrated that the subjects in the vertical incision group had less complication rates and discomfort after labial salivary gland procedure than those in the horizontal incision group. Key words:Salivary gland, biopsy, incision. PMID:23986021

  20. A method of measuring salivary flow rate in the lower labial mucosal region.

    PubMed

    Ogami, K; Sakurai, K; Ando, T

    2004-09-01

    To measure resting whole saliva, draining and spitting methods have been commonly used. However, these methods require the patients' understanding and cooperation. The aim of this study was to establish a method for measuring the salivary flow rate that does not rely on patient's cooperation or the state of the mouth and does not cause any discomfort to patients when performing the measurements. The salivary flow rate in the lower labial mucosal region was measured by means of strips that incorporated the iodo-starch reaction. The salivary flow rate was then calculated on the basis of the number of spots and area of discoloration on the strip. In order to test the validity of these methods, the correlation between these results and resting whole saliva measured by the draining method was also investigated. A positive correlation was found between the salivary flow rate estimated from the area of discoloration on the strip and the resting whole saliva (r=0.678, P=0.01). Therefore, these findings indicate that this is a valid method of measuring the salivary flow rate in the lower labial mucosal region.

  1. Reduced labial temperature in response to sexual films with distractors among women with lower sexual desire.

    PubMed

    Prause, Nicole; Heiman, Julia

    2010-02-01

    Sexual desire variation traditionally has been treated as due to variance in affective response to sexual stimulation, but differences in attention to the stimuli may better account for differences in sexual desire. Determine whether sexual desire varies due to attention biases towards sexual stimuli. Sexual arousal was quantified by physiological (labia minus temperature) and experienced (continuously adjusting a potentiometer) indicators. Twenty-two women who varied in their level of sexual desire attended one laboratory session during which they viewed a neutral nature film, a sexual film, and a sexual film with distractors while their labial temperature and self-reported sexual arousal were recorded. Participants reported and displayed lower sexual arousal during the sexual stimulus with distractors as compared to the sexual film without distractors. While all women reported lower sexual arousal to the sexual film with distractors, women with relatively lower sexual desire also reported lower sexual arousal to the sexual film with no distractors than women with higher sexual desire. Physiologically, women with lower sexual desire exhibited lower labial temperature. Since the predicted lower self-reported and physiological sexual arousal to the sexual stimulus with distractors for the women with lower sexual desire did not emerge, this study does not support that sexual desire levels vary due to differential attention to sexual stimuli.

  2. The labial-coronal effect revisited: Japanese adults say pata, but hear tapa.

    PubMed

    Tsuji, Sho; Gomez, Nayeli Gonzalez; Medina, Victoria; Nazzi, Thierry; Mazuka, Reiko

    2012-12-01

    The labial-coronal effect has originally been described as a bias to initiate a word with a labial consonant-vowel-coronal consonant (LC) sequence. This bias has been explained with constraints on the human speech production system, and its perceptual correlates have motivated the suggestion of a perception-production link. However, previous studies exclusively considered languages in which LC sequences are globally more frequent than their counterpart. The current study examined the LC bias in speakers of Japanese, a language that has been claimed to possess more CL than LC sequences. We first conducted an analysis of Japanese corpora that qualified this claim, and identified a subgroup of consonants (plosives) exhibiting a CL bias. Second, focusing on this subgroup of consonants, we found diverging results for production and perception such that Japanese speakers exhibited an articulatory LC bias, but a perceptual CL bias. The CL perceptual bias, however, was modulated by language of presentation, and was only present for stimuli recorded by a Japanese, but not a French, speaker. A further experiment with native speakers of French showed the opposite effect, with an LC bias for French stimuli only. Overall, we find support for a universal, articulatory motivated LC bias in production, supporting a motor explanation of the LC effect, while perceptual biases are influenced by distributional frequencies of the native language.

  3. Expression of the C. elegans labial orthologue ceh-13 during male tail morphogenesis.

    PubMed

    Stoyanov, Charles-Nicolas; Fleischmann, Martin; Suzuki, Yo; Tapparel, Natacha; Gautron, François; Streit, Adrian; Wood, William B; Müller, Fritz

    2003-07-01

    Hox genes are transcriptional regulators of metazoan body regionalization along the anteroposterior axis that act by specifying positional identity in differentiating cells. ceh-13, the labial orthologue in Caenorhabditis elegans, is expressed both during embryogenesis and post- embryonic development. Using GFP reporter analysis and immunocytochemistry, we discovered a spatiotemporal pattern of gene expression in the male tail during the L3 and L4 larval stages that is TGF-beta pathway-dependent. Analysis of reporter activity in transgenic animals identified a distinct promoter region driving male tail-specific ceh-13 expression. We also report the interspecies conservation of sequence motifs within this region and speculate that, in the course of evolutionary diversification, ceh-13 may have acquired new functionality while conserving its homeotic role.

  4. Sialochemistry of whole, parotid, and labial minor gland saliva in patients with oral lichen planus.

    PubMed

    Gandara, B K; Izutsu, K T; Truelove, E L; Mandel, I D; Sommers, E E; Ensign, W Y

    1987-11-01

    This study was undertaken to determine whether oral lichen planus in otherwise healthy patients is associated with sialochemical abnormalities. Unstimulated and stimulated whole saliva, stimulated parotid saliva, and stimulated labial minor gland saliva were collected from 25 patients with oral lichen planus and from 25 age- and sex-matched controls. Flow rate and salivary concentrations of immunoglobulins A and G, albumin, amylase, lysozyme, lactoferrin, and total protein were determined by standard analytical techniques. Concentrations of inorganic components including sodium, potassium, calcium, chloride, and phosphate were also measured. No significant differences were found between the lichen planus patients and the controls. These findings do not support an association between oral lichen planus and salivary dysfunction in otherwise healthy patients.

  5. Clitoral and labial sizes in women wıth PCOS.

    PubMed

    Köşüş, A; Kamalak, Z; Köşüş, N; Hizli, D; Eser, A

    2016-01-01

    The aim of this study was to examine the external genital features in Turkish women with polycystic ovary syndrome (PCOS). Thirty-two newly diagnosed PCOS cases and 35 healthy women were included the study. All women underwent a thorough gynaecological examination. Clitoral length, and labia minora length and width were recorded. The groups were compared for features of external genital structures. Clitoral and labial lengths were significantly higher in PCOS group. There was a strong correlation between clitoral length and modified Ferriman-Gallwey score. The most effective predictor of PCOS was found to be clitoral length. Clitoral length alone predicted 99.9% of PCOS patients. There were some subclinical genital changes in women with PCOS. These changes in PCOS patients may be a sign of hyperandrogenism and might have diagnostic value in indistinct cases.

  6. Standardisation of labial salivary gland histopathology in clinical trials in primary Sjögren's syndrome.

    PubMed

    Fisher, Benjamin A; Jonsson, Roland; Daniels, Troy; Bombardieri, Michele; Brown, Rachel M; Morgan, Peter; Bombardieri, Stefano; Ng, Wan-Fai; Tzioufas, Athanasios G; Vitali, Claudio; Shirlaw, Pepe; Haacke, Erlin; Costa, Sebastian; Bootsma, Hendrika; Devauchelle-Pensec, Valerie; Radstake, Timothy R; Mariette, Xavier; Richards, Andrea; Stack, Rebecca; Bowman, Simon J; Barone, Francesca

    2017-07-01

    Labial salivary gland (LSG) biopsy is used in the classification of primary Sjögren's syndrome (PSS) and in patient stratification in clinical trials. It may also function as a biomarker. The acquisition of tissue and histological interpretation is variable and needs to be standardised for use in clinical trials. A modified European League Against Rheumatism consensus guideline development strategy was used. The steering committee of the ad hoc working group identified key outstanding points of variability in LSG acquisition and analysis. A 2-day workshop was held to develop consensus where possible and identify points where further discussion/data was needed. These points were reviewed by a subgroup of experts on PSS histopathology and then circulated via an online survey to 50 stakeholder experts consisting of rheumatologists, histopathologists and oral medicine specialists, to assess level of agreement (0-10 scale) and comments. Criteria for agreement were a mean score ≥6/10 and 75% of respondents scoring ≥6/10. Thirty-nine (78%) experts responded and 16 points met criteria for agreement. These points are focused on tissue requirements, identification of the characteristic focal lymphocytic sialadenitis, calculation of the focus score, identification of germinal centres, assessment of the area of leucocyte infiltration, reporting standards and use of prestudy samples for clinical trials. We provide standardised consensus guidance for the use of labial salivary gland histopathology in the classification of PSS and in clinical trials and identify areas where further research is required to achieve evidence-based consensus. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  7. Labial frenectomy with Nd:YAG laser and conventional surgery: a comparative study.

    PubMed

    Medeiros Júnior, Rui; Gueiros, Luiz Alcino; Silva, Igor Henrique; de Albuquerque Carvalho, Alessandra; Leão, Jair Carneiro

    2015-02-01

    Labial frenulums are sagittal fibrous folds of oral mucosa with a periosteal insertion that extend from the lips to the alveolar or gingival mucosa. Occasionally, they assume inadequate size or location and may lead to functional and esthetic limitations. The aim of the present study was to compare pre-, trans-, and postsurgical clinical parameters of labial frenectomies performed with conventional surgery and neodymium-doped yttrium aluminum garnet (Nd:YAG) laser. Forty individuals were assessed as a convenience sample and were divided into two groups according to the treatment: group 1 (G1), conventional surgery (n = 22), and G2, Nd:YAG laser surgery (n = 18). Clinical parameters such as frenulum insertion, location, bleeding, surgical time, suturing, preoperative fear, and postoperative discomfort/functional limitations were evaluated. All surgeries were performed by the same operator, and the level of fear, pain, and discomfort related to oral functions were assessed with a visual numeric scale. Most of the frenulums (90%) were classified as papillary or transpapillary insertion. Preoperative fear was similar between groups (p = 0.593). All G2 patients did not require suture (p < 0.001), did not bleed during the procedure (p < 0.001), and had surgical time diminished (p < 0.001). No significant statistical difference regarding pain or oral function could be observed. Three individuals (7.5%) experienced postsurgical complications. Nd:YAG laser frenectomies reduces transoperative bleeding, avoiding the need of suturing, and promotes a significant reduction of surgical time in comparison with conventional surgery. Therefore, further studies are necessary to provide a complete understanding and standardization of the technique as well as the expected clinical results.

  8. Bodily labializing lateral incisors: 3D analysis using finite element method.

    PubMed

    Geramy, Allahyar

    2013-01-01

    Among all tooth types and movements, bodily labializing the upper lateral incisors is a challenging one. The main goal of this study is to introduce and analyze a method to labialize palatally erupted lateral incisors. Five three dimensional finite element models were designed in SolidWorks 2010 of a segment of maxilla containing the upper left anterior teeth (with the lateral incisor in palatal position), their brackets, their PDLs, the spongy and cortical bone. A segment of 0.016 wire passing through the central incisor and canine brackets (bypassing the lateral incisor bracket) and a designed hook in the lateral incisor bracket (which comprises an inventory approach/design to treat a palatally erupted tooth). The hook and vertical bypassed segment height were 8, 10, 11.5 (stage 1), 9.5 (stage 2) and 9.45 mm (stage 3). Two equal forces (0.15 N each) were applied. Tooth displacements were recorded. A hook length of 8 mm resulted in a tipping movement (apical = -7.78 × 10(-5) mm; incisal = 3.8 × 10(4) mm). The other two caused root movement. Stage 2 (hook = 9.5 mm) resulted in root movement (-1.4 × 10(-4) mm in incisal; 1.58 × 10(4) mm in apical area). Hook length = 9.45 produced bodily movement (incisal = 7.1 × 10(5) mm; apical = 6.9 × 10(5) mm). A definite length of the hook was shown to produce bodily movement. This definite length of hook in combination with the same length of bypassed wire can be applied to produce bodily movement of the lateral incisor. An intrusive component can also be added.

  9. A case of recurrent labial adhesions in a 15-month-old child with asymptomatic non-classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency.

    PubMed

    Janus, Dominika; Wojcik, Malgorzata; Malunowicz, Ewa; Starzyk, Jerzy B

    2012-01-01

    Labial adhesions (synechia vulvae) are a relatively common disorder of the external genitalia in prepubertal girls. They usually occur between 3 months and 6 years of age, with a peak between 13 and 23 months of life. In the majority of cases, labial adhesions are asymptomatic and noticed by the parents or a physician during a routine physical examination. Frequently, they cause recurrent urinary tract infections. This report presents the case of a 15-month-old girl with recurrent labial adhesions and urinary tract infections. She was followed-up by a urologist from the age of 3 months, treated topically (estriol cream 1 mg/g and emollients) and surgically. No signs of androgenization were seen apart from advanced bone age. Urinary steroid profile and molecular analysis confirmed the diagnosis of non-classic congenital adrenal hyperplasia (NCCAH) due to 21-hydroxylase deficiency. In the described case, a coincidence of NCCAH and labial adhesion cannot be excluded particularly in view of the resolving of urinary tract infections at the same time as resolving of labial adhesions. However, it seems that in cases of recurrent labial adhesion/synechia that require repeated surgical interventions in view of ineffectiveness of conservative treatment - as it was observed in the presented case - one should consider searching for NCCAH. This may allow not only for the causal treatment of labial adhesions but, above all, NCCAH and, in consequence, the prevention of intensification of virilization, hirsutism, menstrual cycle, and fertility disturbances that are observed starting from puberty.

  10. Monotypic plasma cells in labial salivary glands of patients with Sjögren's syndrome: prognosticator for systemic lymphoproliferative disease.

    PubMed Central

    Bodeutsch, C; de Wilde, P C; Kater, L; van den Hoogen, F H; Hené, R J; van Houwelingen, J C; van de Putte, L B; Vooijs, G P

    1993-01-01

    AIMS: To determine the prevalence of plasma cell monotypia in labial salivary gland tissue of patients with and without Sjögren's syndrome, and to evaluate its relation to the development of systemic monoclonal lymphoproliferative disorders. METHODS: A quantitative immunohistological study was performed on labial salivary gland tissue of 45 patients with Sjögren's syndrome, 18 with rheumatoid arthritis without Sjögren's syndrome, and 80 healthy controls. In none of the patients with Sjögren's syndrome was there evidence of systemic monoclonal lymphoproliferative disease at the time of biopsy. RESULTS: Monotypic plasma cell populations, defined by a kappa:lambda ratio of > or = 3, were only observed in older patients (above 43 years) with Sjögren's syndrome. In almost all these patients monotypic plasma cell populations were present in multiple labial salivary gland tissues and the IgM/kappa monotypia was observed most frequently. The prevalence of monotypic plasma cell populations in the group with Sjögren's syndrome was 22% (10/45) and there was no significant predilection for primary Sjögren's syndrome. Of special clinical interest was the observation that progression to systemic monoclonal lymphoproliferative disease had occurred exclusively in this subgroup of patients with Sjögren's syndrome, with a prevalence of 30% (3/10). CONCLUSION: Quantitative immunohistological examination of labial salivary gland tissues provides pathologists with a simple method to select those patients with Sjögren's syndrome who have an increased relative risk at the time of biopsy to develop benign or malignant lymphoproliferative disorders. PMID:8459032

  11. [Histochemical properties of secretory granules and fine structure of terminal portion in the Japanese Macaque labial gland].

    PubMed

    Tsutusumi, T; Kurabuchi, S; Aiyama, S

    1989-06-01

    The terminal portion of the Japanese macaque (Macaca fuscata) labial gland was examined ultrastructurally and histochemically. The results obtained are as follows. 1) The Japanese macaque, Macaca fuscata has the upper and the lower labial glands, which can be described as a compound tubulo-acinar gland. 2) The terminal portion of the labial gland appears to be consisted of the mucous acini and the demilunes when examined with the light microscope. 3) The secretory granules containing in the glandular cells of the mucous acini and the demilunes are negative with napthol yellow S, ninhydrin-Schiff and DMAB nitrite. 4) The secretory granules containing in the glandular cells of mucous acini stain intensely with PAS, alcian blue (pH1.0, 2.5, 3.5), colloidal iron and PA-methenamine silver, while those of demilunes are negative with alcian blue (pH1.0). The glandular cells of demilune with the PA-methenamine silver method shows weak positive granules and positive granules which are limited to the hallo of them. 5) In the mucous acini the mucous granules are ejected from glandular cells by the process of exocytosis. 6) The myoepithelial cell can be seen in the terminal portion. This cell surrounds the acini with long processes. These findings suggest that the glandular cells of the demilune have the granules containing mucopoly saccharides and a small quantity of protein in addition to the mucous granules, although the terminal portion of the Japanese macaque labial gland is nearly composed of mucous cells.

  12. Detection of AA-type amyloid protein in labial salivary glands.

    PubMed

    Sacsaquispe, Sonia-Julia; Antúnez-de Mayolo, Eleazar-Antonio; Vicetti, Rodolfo; Delgado, Wilson-Alejandro

    2011-03-01

    Among the diverse forms of amyloidosis, secondary type is the most frequent one. Diagnosis of amyloid deposition is based on the identification of the fibrillary protein amyloid by means of Congo Red (CR) or crystal violet (CV) stains, but these techniques do not differentiate between the different types of amyloid fibrils. The aim of this study was to identify by immunofluorescence (IF) AA amyloid a pathological fibrillar low-molecular-weight protein formed by cleavage of serum amyloid A (SAA) protein in labial salivary gland (LSG) biopsies from patients with secondary amyloidosis. 98 LSG were studied, 65 were from patients with secondary amyloidosis and 33 from subjects with chronic inflammatory diseases without evidence of this anomaly. All sections were stained with hematoxylin and eosin (H &E), CV, CR and IF using anti-AA antibodies. Positive and negative controls were used for all techniques. CV and CR demonstrated that the amyloid substance was found mainly distributed periductally (93.8%), followed by periacinar and perivascular locations (p <0.001); however, the IF demonstrated that amyloid AA substance predominates in the periacinar area (73.8%), followed by periductal and perivascular locations (p <0.001). IF has a sensitivity of 83%, 100% of specificity, 100% of predictive positive value and 75% of predictive negative value. The results of this study confirm the efficacy of the LSG biopsy as a highly reliable method for diagnosis of secondary amyloidosis.

  13. Anterior organization of the Caenorhabditis elegans embryo by the labial-like Hox gene ceh-13.

    PubMed

    Brunschwig, K; Wittmann, C; Schnabel, R; Bürglin, T R; Tobler, H; Müller, F

    1999-04-01

    The Caenorhabditis elegans lin-39, mab-5 and egl-5 Hox genes specify cell fates along the anterior-posterior body axis of the nematode during postembryonic development, but little is known about Hox gene functions during embryogenesis. Here, we show that the C. elegans labial-like gene ceh-13 is expressed in cells of many different tissues and lineages and that the rostral boundary of its expression domain is anterior to those of the other Hox genes. By transposon-mediated mutagenesis, we isolated a zygotic recessive ceh-13 loss-of-function allele, sw1, that exhibits an embryonic sublethal phenotype. Lineage analyses and immunostainings revealed defects in the organization of the anterior lateral epidermis and anterior body wall muscle cells. The epidermal and mesodermal identity of these cells, however, is correctly specified. ceh-13(sw1) mutant embryos also show fusion and adhesion defects in ectodermal cells. This suggests that ceh-13 plays a role in the anterior organization of the C. elegans embryo and is involved in the regulation of cell affinities.

  14. Conserved regulation of the Caenorhabditis elegans labial/Hox1 gene ceh-13.

    PubMed

    Streit, Adrian; Kohler, Reto; Marty, Thomas; Belfiore, Marco; Takacs-Vellai, Krisztina; Vigano, Maria-Alessandra; Schnabel, Ralf; Affolter, Markus; Müller, Fritz

    2002-02-15

    Caenorhabditis elegans contains a set of six cluster-type homeobox (Hox) genes that are required during larval development. Some of them, but unlike in flies not all of them, are also required during embryogenesis. It has been suggested that the control of the embryonic expression of the worm Hox genes might differ from that of other species by being regulated in a lineal rather than a regional mode. Here, we present a trans-species analysis of the cis-regulatory region of ceh-13, the worm ortholog of the Drosophila labial and the vertebrate Hox1 genes, and find that the molecular mechanisms that regulate its expression may be similar to what has been found in species that follow a regulative, non-cell-autonomous mode of development. We have identified two enhancer fragments that are involved in different aspects of the embryonic ceh-13 expression pattern. We show that important features of comma-stage expression depend on an autoregulatory input that requires ceh-13 and ceh-20 functions. Our data show that the molecular nature of Hox1 class gene autoregulation has been conserved between worms, flies, and vertebrates. The second regulatory sequence is sufficient to drive correct early embryonic expression of ceh-13. Interestingly, this enhancer fragment acts as a response element of the Wnt/WG signaling pathway in Drosophila embryos.

  15. Immunoglobulin deposits in labial mucosal epithelium of patients suspected of Sjögren's syndrome.

    PubMed

    Oxholm, P; Manthorpe, R; Oxholm, A; Schiødt, M

    1986-02-01

    Lower lip biopsies from twenty-three consecutive patients under evaluation for Sjögren's syndrome, and from six normal controls, were investigated for deposits of immunoglobulins, fibrinogen and C3, using a direct immunofluorescence technique. Deposits of both IgG and IgA were demonstrated in the mucosal epithelium in three of six patients with primary Sjögren's syndrome. Similar IgG deposits were found in two of three patients with xerostomia and in one of three patients with Sjögren's syndrome secondary to rheumatoid arthritis. Immunoglobulins were located in close relation to cell surfaces in the basal and suprabasal layers of the epithelium. Double labelling experiments indicated a partial topographic concordance between the immunoglobulin deposits and OKT6 positive Langerhans cells in the epithelium. No deposits of immunoglobulins, fibrinogen or C3 were found in the remaining eleven patients and six normal controls. We conclude that deposits of IgG and IgA in the labial mucosal epithelium seem to be a characteristic finding in patients with primary Sjögren's syndrome as well as in patients with xerostomia. The diagnostic value of this new observation needs to be clarified in future studies.

  16. Estimating Vocal Effort from the Aerodynamics of Labial Fricatives: A Feasibility Study.

    PubMed

    Meynadier, Yohann; El Hajj, Anita; Pitermann, Michel; Legou, Thierry; Giovanni, Antoine

    2017-09-12

    Vocal effort in loud voice is produced with increased subglottal pressure during vowels and increased supraglottal pressure during consonants. In the paper, our main objective is to check whether it was supported by a parallel increase in the airflow resistance of the laryngeal articulator and of the supralaryngeal articulator, here the lips. For this comparison, our choice fell on the fricative consonants, as their production allows perfectly synchronous air pressure and airflow measurements. Also, the calculation of the real instantaneous aerodynamic resistance is possible with fricatives-as it is with vowels-whereas it is not possible with plosives. The present feasibility study on a healthy subject is based on direct subglottal and intraoral pressures and airflow measured for /f/ or /v/ and from the contiguous vowel produced in VCVCV nonsense words at different levels of intensity. The results support that the airflow resistances at the lips and that at the larynx are quite parallel. The airflow resistance at the lips during labial fricative production could provide a good picture of the laryngeal resistance during the production of continuous speech. This suggests clinical applications using both noninvasive inferred measurements of subglottal pressure variation and direct noninferred airflow measurements from more natural speech production tasks. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  17. Labial ring flap: a new flap for metaidoioplasty in female-to-male transsexuals.

    PubMed

    Takamatsu, A; Harashina, T

    2009-03-01

    To describe the technical details of our experience in performing metaidoioplasty. After the first officially approved sex-reassignment surgery on a patient with transsexualism was performed in Japan, we performed metaidoioplasties on 69 female-to-male transsexuals between 1998 and 2007. Oophorohysterectomy and metaidoioplasty were performed by a one-stage procedure. Hage's technique was used on the first 26 cases. The labial ring flap technique was performed on 43 patients (aged 18-33 years) after 2005. This new technique uses all the labia minora skin incorporated with the anterior vaginal flap for urethral lengthening. The clitoral chordee is also released by this procedure. Using this method, we obtained a neo-urethra of a good diameter and a more male-like appearance for external genitalia along with a minipenis. The postoperative course was uneventful in 28 of 43 cases. Urethral fistula occurred in 12 cases, which was spontaneously closed in eight cases. Four other cases required secondary repair. Three cases with neo-urethral stenosis were treated by urethral dilation. Of the 43 cases, 28 can void in a standing position. For five patients who desired a larger phallus, various phalloplasty techniques were performed subsequently. Satisfactory urine stream and appearance were achieved. Metaidoioplasty with minimal scarring can be selected independently or as the first step followed by phalloplasty if the patient requires such an operation.

  18. A finite element model of the tuning slot of labial organ pipes.

    PubMed

    Rucz, Péter; Augusztinovicz, Fülöp; Angster, Judit; Preukschat, Tim; Miklós, András

    2015-03-01

    An acoustic model suitable for the characterization of tuning slots of labial organ pipes is presented in this paper. Since the tuning slot arrangement is similar (but not identical) to that of toneholes in woodwind instruments, the adaptability of the well-established tonehole model for the specific problem is examined. A numerical model utilizing the finite element (FE) and perfectly matched layer techniques is set up for the simulation of tuning slots with design parameters varying over a wide range. Analytical tonehole models and the proposed numerical tuning slot model are both combined with analytical one-dimensional waveguide models to predict the acoustic behavior of tuning slot pipes. Comparison to measurements carried out on experimental pipes proves that the hybrid waveguide/FE model can predict the most important properties of the tuning slot pipe with good accuracy. The finite element method (FEM) also overcomes the limitations of traditional tonehole models relying on the equivalent T-circuit approximation. By means of the FE model the eigenfrequency-structure and its impact on the character of the sound can be foretold in the design phase, by which a more efficient scaling of tuning slot pipes can be achieved.

  19. The frenectomy: a comparison of classic versus laser technique.

    PubMed

    Epstein, S R

    1991-08-01

    When an abnormal labial frenum causes certain complications, frenectomy should be considered. In this article, the indications for frenectomy are outlined, classical and laser frenectomy techniques are described, and the advantages and disadvantages of both techniques are discussed.

  20. Vaginal labiaplasty: current practices and a simplified classification system for labial protrusion.

    PubMed

    Motakef, Saba; Rodriguez-Feliz, Jose; Chung, Michael T; Ingargiola, Michael J; Wong, Victor W; Patel, Ashit

    2015-03-01

    Vaginal labiaplasty has been described for the management of functional and aesthetic problems associated with protrusion of the labia minora. Despite increasing numbers of procedures performed, there is a paucity of data to guide treatment paradigms. This systematic review aims to establish a simple, unifying classification scheme for labial protrusion and summarize current labiaplasty techniques and practices. A systematic literature review was performed using the PubMed database. Additional articles were selected after reviewing references of identified articles. The search returned 247 articles. After applying inclusion criteria to identify prospective and retrospective studies evaluating different techniques, outcomes, complications, and patient satisfaction, 19 articles were selected. Labiaplasty of the labia minora was described in 1949 patients. Seven different surgical techniques were used for labiaplasty, including deepithelialization, direct excision, W-shaped resection, wedge resection, composite reduction, Z-plasty, and laser excision. Patient satisfaction rates for each technique ranged from 94 to 100 percent. The most common postoperative complication for all techniques was wound dehiscence (4.7 percent). Key areas for perioperative patient management were defined. Labiaplasty is safe and carries a high satisfaction rate. However, current practices remain exceedingly diverse. The authors propose a simplified classification system based on the distance of the lateral edge of the labia minora from that of the labia majora, rather than from the introitus. Key areas for perioperative patient management include patient anesthesia, resection technique used, wound closure, and postoperative care. Further randomized studies using a standardized classification system are required to better compare different techniques and establish best practices.

  1. Differences in psychological traits between lingual and labial orthodontic patients: perfectionism, body image, and the impact of dental esthetics.

    PubMed

    Bellot-Arcís, Carlos; Ferrer-Molina, Marcela; Carrasco-Tornero, Ángel; Montiel-Company, José María; Almerich-Silla, José Manuel

    2015-01-01

    To examine some of the patients' psychological traits in relation to their levels of perfectionism and their body image, and to discover whether these differ between lingual and labial orthodontic patients. A cross-sectional study was designed with a consecutive sample of 80 patients attending a private orthodontic office. Three questionnaires were used to assess the patients' body image and level of perfectionism. The mean age was 33 years. The men numbered 32 and the women 48. The validated Spanish version of the Psychosocial Impact of Dental Aesthetic Questionnaire (PIDAQ) was used to assess the psychosocial impact of their dental esthetics. The Multidimensional Perfectionism Scale (MPS) was used to assess how perfectionist the patients were. A version of the Multidimensional Body-Self Relations Questionnaire (MBSRQ) was used for assessment of their body image. Student's t-test was used to compare the means and 95% confidence intervals (P < .05), and a logistic regression model was used for multivariate analysis. The PIDAQ (55.4 vs 60, P  =  .218) and MBSRQ (128.7 vs 125.9, P  =  .523) results of the patients who chose lingual orthodontics did not differ significantly from those who opted for labial orthodontics. However, the MPS scores of the lingual orthodontic patients were significantly higher (95.9 vs 86.3, P  =  .044), and high social class, over 30 years of age, and perfectionist traits were significant independent variables in this group. This pilot study may indicate that lingual orthodontic patients are more perfectionists than labial orthodontic patients.

  2. Basal lamina disorganisation of the acini and ducts of labial salivary glands from patients with Sjögren's syndrome: association with mononuclear cell infiltration

    PubMed Central

    Molina, C; Alliende, C; Aguilera, S; Kwon, Y‐J; Leyton, L; Martínez, B; Leyton, C; Pérez, P; González, M‐J

    2006-01-01

    Objective To study the expression of laminin and type IV collagen as biomarkers of the organisation of the basal lamina of acini and ducts in labial salivary glands from patients with Sjögren's syndrome, and to relate this organisation to inflammatory cell invasion of acini and ducts. Methods Immunohistochemistry for laminin and type IV collagen was undertaken on sections of labial salivary glands from 30 patients with Sjögren's syndrome, 10 control subjects, and 24 controls with chronic sialoadenitis. Immunohistochemistry reaction, alterations to cell morphology, and the presence of inflammatory cells in acini and ducts were evaluated and scored using a semiquantitative method. Results Changes in the expression of laminin and type IV collagen in the basal lamina of acini and ducts of labial salivary glands from patients with Sjögren's syndrome were more pronounced than in labial salivary glands from control groups. A remarkable characteristic was the disorganisation of the basal lamina in the labial salivary glands in Sjögren's syndrome. The pattern of immunoreactivity of the basal lamina of other structures (for example, blood vessels) did not change. In Sjögren's syndrome, invasion of cytotoxic T lymphocytes was only observed in acini and ducts which had a disorganised basal lamina. Conclusions The high state of disorganisation of the basal lamina of acini and ducts could allow invasion of cytotoxic T lymphocytes in Sjögren's syndrome, contributing to cell death and ductal hyperplasia. PMID:16014676

  3. Patient Satisfaction of Surgical Treatment of Clitoral Phimosis and Labial Adhesions Caused by Lichen Sclerosus

    PubMed Central

    King, Michelle; Rieff, Mollie; Krapf, Jill; Goldstein, Andrew T.

    2015-01-01

    with surgical correction of clitoral phimosis and lysis of vulvar adhesions for VGF caused by LS. Patients reported improvement in clitoral sensation and ability to achieve orgasm, as well as decreased dyspareunia. Surgical correction of vulvar scarring is a viable option to restore vulvar anatomy and sexual function in appropriate candidates with anogenital LS. Flynn AN, King M, Rieff M, Krapf J, and Goldstein AT. Patient satisfaction of surgical treatment of clitoral phimosis and labial adhesions caused by lichen sclerosus. Sex Med 2015;3:251–255. PMID:26797058

  4. Patient Satisfaction of Surgical Treatment of Clitoral Phimosis and Labial Adhesions Caused by Lichen Sclerosus.

    PubMed

    Flynn, Anne N; King, Michelle; Rieff, Mollie; Krapf, Jill; Goldstein, Andrew T

    2015-12-01

    caused by LS. Patients reported improvement in clitoral sensation and ability to achieve orgasm, as well as decreased dyspareunia. Surgical correction of vulvar scarring is a viable option to restore vulvar anatomy and sexual function in appropriate candidates with anogenital LS. Flynn AN, King M, Rieff M, Krapf J, and Goldstein AT. Patient satisfaction of surgical treatment of clitoral phimosis and labial adhesions caused by lichen sclerosus. Sex Med 2015;3:251-255.

  5. Attitudes Regarding Labial Hypertrophy and Labiaplasty: A Survey of Members of the Society of Gynecologic Surgeons and the North American Society for Pediatric and Adolescent Gynecology.

    PubMed

    Westermann, Lauren B; Oakley, Susan H; Mazloomdoost, Donna; Crisp, Catrina C; Kleeman, Steven D; Benbouajili, Janine M; Pauls, Rachel N

    2016-01-01

    The aim of this study was to describe gynecologists' attitudes toward labial hypertrophy and explore possible differences among providers for pediatric/adolescent patients. This was an institutional review board-approved, cross-sectional survey of physician attendees at 2 national meetings in 2014: the Society of Gynecologic Surgeons (SGS) and the North American Society for Pediatric and Adolescent Gynecology (NASPAG). The survey was designed to query demographics and impressions regarding labial hypertrophy and labiaplasty. Three hundred sixty-five surveys were completed (response rate, 50%); 268 were analyzed: 55% from SGS and 45% from NASPAG. Most were older than 41 years; 170 (63%) were women, and 93 (35%) were men. More men than women attended SGS (60%); however, women were the majority at NASPAG (94%).Most respondents believed labial hypertrophy to be infrequently reported and "a condition that impacts body image." Common symptoms were "discomfort with exercise" and "dissatisfaction with appearance naked." The majority felt this to impact sexual function "in some cases," citing "self-esteem" and "comfort" most often.Concerning therapies for provided labial hypertrophy, 83% of practitioners provide reassurance, whereas 77% would offer labiaplasty. Expertise with labiaplasty varied; 28% felt "very comfortable," and 11% felt "very uncomfortable."Provider preference for treatment differed based on meeting attendance. After logistic regression controlling for sex and age, attendance at SGS remained associated with offering labiaplasty (P = 0.001; odds ratio, 4.1; 95% confidence interval, 1.8-9.3), whereas NASPAG attendance was associated with providing reassurance (P = 0.008; odds ratio, 0.30; 95% confidence interval, 0.10-0.70). Although the majority surveyed view labial hypertrophy to be bothersome, gynecologists caring for our youngest patients are more likely to provide reassurance. Consensus guidelines are needed to aid practitioners in appropriate management

  6. Germinal centres in diagnostic labial gland biopsies of patients with primary Sjögren's syndrome are not predictive for parotid MALT lymphoma development.

    PubMed

    Haacke, Erlin A; van der Vegt, Bert; Vissink, Arjan; Spijkervet, Fred K L; Bootsma, Hendrika; Kroese, Frans G M

    2017-10-01

    Patients with primary Sjögren's syndrome (pSS) have an increased risk of developing non-Hodgkin's lymphoma (NHL), particularly parotid gland mucosa-associated lymphoid tissue (MALT) lymphomas. Presence of germinal centres (GCs) in labial gland biopsies has been suggested as predictive factor for NHL. We assessed whether presence of GCs is increased in labial gland biopsies from patients with pSS who developed parotid MALT lymphoma, the dominant NHL-subtype in pSS, compared with patients with pSS who did not develop lymphoma. Eleven labial gland biopsies from patients with pSS that were taken prior to parotid MALT lymphoma development were compared with biopsies of 22 matched pSS controls (1:2) who did not develop lymphoma. Biopsies were evaluated for GCs (H&E and Bcl6). Labial gland biopsies of pSS MALT lymphoma patients, revealed GCs in 2/11 (18%) H&E sections and 3/11 (27%) Bcl6 stained sections. In controls, GCs were present in 4/22 (18%) of H&E sections and 5/22 (23%) of Bcl6 stained sections. Presence of GCs in labial gland biopsies does not differ between patients with pSS that develop parotid MALT lymphoma and patients with pSS who do not develop lymphoma. The presence of GCs in labial gland biopsies is therefore not a predictive factor for pSS-associated parotid MALT lymphomas. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  7. An articulatory basis for the labial-to-coronal effect: /pata/ seems a more stable articulatory pattern than /tapa/.

    PubMed

    Rochet-Capellan, Amélie; Schwartz, Jean-Luc

    2007-06-01

    This paper investigates the coordination between the jaw, the tongue tip, and the lower lip during repetition with rate increase of labial-to-coronal (L(a)C(o)) consonant-vowel-consonant-vowel disyllables (e.g., /pata/) and coronal-to-labial (C(o)L(a)) ones (e.g., /tapa/) by French speakers. For the two types of disyllables: (1) the speeding process induces a shift from two jaw cycles per disyllable to a single cycle; (2) this shift modifies the coordination between the jaw and the constrictors, and (3) comes with a progression toward either a L(a)C(o) attractor [e.g., (/pata/ or /tapa/) --> /patá/ --> /ptá/] or a C(o)L(a) one (e.g., /pata/ or /tapa/ --> /tapá/ --> /tpá/). Yet, (4) the L(a)C(o) attractor is clearly favored regardless of the initial sequencing. These results are interpreted as evidence that a L(a)C(o) CVCV disyllable could be a more stable coordinative pattern for the lip-tongue-jaw motor system than a C(o)L(a) one. They are discussed in relation with the so-called LC effect that is the preference for L(a)C(o) associations rather than C(o)L(a) ones in CV.CV disyllables in both world languages and infants' first words.

  8. Modified frenectomy: a review of 3 cases with concerns for esthetics.

    PubMed

    Bhusari, Prashant A; Verma, Shiras; Maheshwari, Shubhra; Belludi, Sphoorthi

    2013-08-01

    The maxillary labial frenum is a normal anatomical structure in the oral cavity. An abnormal labial frenum causes localized gingival recession and midline diastema, both of which can interfere with oral hygiene procedures, and eventually affect esthetics. When the frenum maintains its high papillary attachment, frenectomy is the treatment of choice. Though this technique has undergone many modifications, the zone of attachment and esthetics in the anterior maxillary region have been neglected. This article highlights a new frenectomy technique that results in good esthetics, excellent color match, gain in attached gingiva, and healing by primary intention at the site of thick, extensive abnormal frena.

  9. Immunoglobulin-producing cells in labial salivary glands of patients with rheumatoid arthritis and systemic lupus erythematosus.

    PubMed

    Matthews, J B; Potts, A J; Hamburger, J; Struthers, G; Scott, D G

    1986-11-01

    The distribution of immunoglobulin-producing cells within labial salivary glands from normal individuals (n = 7) and patients with rheumatoid arthritis (n = 10) and systemic lupus erythematosus (n = 9) was studied using morphometric and indirect immunoperoxidase methods. Cell counts revealed a significant increase in the density of IgG cells within glands from both patient groups compared with glands from normal individuals. No significant differences in the density of IgA- or IgM-producing cells between the 3 groups were observed although large individual variations were apparent. Histomorphometric studies showed an increase in the lymphoid compartment and a decrease in glandular elements within glands from the 2 patient groups. When data for all specimens were pooled a significant positive correlation was obtained between the percent area of stromal lymphoid tissue and density of IgG and IgM cells.

  10. [Biopsy of labial salivary glands and lacrimal glands in the diagnosis of Sjögren's syndrome].

    PubMed

    Xu, K; Kazuo, T

    1997-05-01

    To determine the diagnostic value for Sjögren's syndrome (SS) by evaluating the presence of focal adenitis in labial salivary gland (LSG) and lacrimal gland (LG) biopsy specimens. 109 suspected cases with SS underwent the biopsies. The diagnostic criteria of Fox et al. were followed. Both Chisholm-Manson's grading standard and Greenspan's focus score were used for the evaluation. Myoepithelial islands and severe lymphocyte infiltration with germinal centers were observed only in LG biopsy specimens. The lymphocytic foci scored of LG were significantly higher than that of LSG in 23 cases having both biopsy results. The evaluation of both kinds of specimen for such a patient was significantly more effective in diagnosing SS than using either one of them alone. We recommend that both LSG and LG biopsies be performed in patients suspected of having SS to reduce false negative results and improve diagnostic accuracy.

  11. Q-switched alexandrite laser treatment of facial and labial lentigines associated with Peutz-Jeghers syndrome.

    PubMed

    Li, Yan; Tong, Xiaorong; Yang, Jing; Yang, Liu; Tao, Juan; Tu, Yating

    2012-08-01

    The Q-switched alexandrite laser used at 752 nm, a wavelength well absorbed by melanin relative to other optically absorbing structures in skin, causes highly selective destruction of pigment-laden cells. In addition, the 75-nanosecond pulse duration produced by this laser approximates the thermal relaxation time for melanosomes, thereby confining the energy to the target. Facial and labial dark brown macules quickly identify patients with Peutz-Jeghers syndrome. These lentigines may be cosmetically disfiguring. The Q-switched alexandrite laser produces clinically significant fading of mucocutaneous melanosis in association with Peutz-Jeghers syndrome without complications often seen with other therapeutic modalities. To evaluate the efficacy and safety of the Q-switched alexandrite laser in treating facial and labial lentigines of Peutz-Jeghers syndrome. 43 patients diagnosed with Peutz-Jeghers syndrome were treated and studied in our laser center from 2000 to 2010. We used a Q-switched alexandrite laser specified with 75 ns pulse length, emitting at 752 nm and with a 2.4 mm-diameter spot size. The lesional skin was irradiated with fluences of 5-7 J/cm2. The treatment intervals were 3 months. After treatment with the Q-switched alexandrite laser, 55.8% (24/43) of the patients had excellent results in which more than 75% of the pigments cleared, and 44.2% (19/43) showed good results. Three sessions were required to obtain excellent results. We observed no serious complications. We obtain a successful outcome in the treatment of these lentigines with Q-switched alexandrite laser and consider it the treatment of choice for these lesions. © 2012 John Wiley & Sons A/S.

  12. Variations in the frenal morphology in the diverse population: A clinical study

    PubMed Central

    Jindal, Vikas; Kaur, Rupinder; Goel, Amit; Mahajan, Atika; Mahajan, Neha; Mahajan, Atin

    2016-01-01

    Background: The upper labial frenum is a normal anatomic structure with inherent morphological variations. Frenum has variations depending upon the attachment of fibers along with the presence of structural variations. Aim: The aim of this study was to evaluate the prevalence of frenal variations in a diverse ethnic population of Sundernagar, Himachal Pradesh. Materials and Methods: This study was conducted on 500 subjects within age group of 16–40 years (285 females, 215 males). Intraoral examination was done to evaluate the variations in frenum and photographs were taken. Results: In this study, depending upon structural variations, normal frenum was most common followed by frenum with nodule while frenum with appendix was found to be least common. However, no significant difference was found between males and females (P > 0.05) with respect to all frenal attachments. Furthermore, other structural variations were found in the diverse population of Sundernagar, Himachal Pradesh. Conclusion: Upper labial frenum is a small anatomical landmark in the oral cavity found to have diverse morphology. The dentist needs to give due importance for frenum assessment during the oral examination. PMID:27563207

  13. Quantitative assessment of oral mucosa and labial minor salivary glands in patients with Sjögren’s syndrome using swept source OCT

    PubMed Central

    Grulkowski, Ireneusz; Nowak, Jan K.; Karnowski, Karol; Zebryk, Paweł; Puszczewicz, Mariusz; Walkowiak, Jaroslaw; Wojtkowski, Maciej

    2013-01-01

    Three-dimensional imaging of the mucosa of the lower lip and labial minor salivary glands is demonstrated in vivo using swept source optical coherence tomography (OCT) system at 1310 nm with modified interface. Volumetric data sets of the inner surface of the lower lip covering ~230 mm2 field are obtained from patients with Sjögren’s syndrome and a control group. OCT enables high-resolution visualization of mucosal architecture using cross-sectional images as well as en-face projection images. Comprehensive morphometry of the labial minor salivary glands is performed, and statistical significance is assessed. Statistically significant differences in morphometric parameters are found when subgroups of patients with Sjögren’s syndrome are analyzed. PMID:24466492

  14. Dental cone beam computed tomography analyses of postoperative labial bone thickness in maxillary anterior implants: comparing immediate and delayed implant placement.

    PubMed

    Miyamoto, Yasukazu; Obama, Tadakazu

    2011-06-01

    This study aimed to evaluate the influence of labial alveolar bone thickness and the corresponding vertical bone loss on postoperative gingival recessions around anterior maxillary dental implants. Using cone beam computed tomography (CBCT) scanning, the temporal changes of three-dimensional images of alveolar bone were monitored to determine hard and soft tissue outcomes of two different implant placement techniques: delayed two-stage and immediate placement. Furthermore, for the delayed two-stage placement, guided bone regeneration was applied using either nonresorbable or resorbable membranes combined with anorganic bovine bone matrix. The comparative results suggested that gingival recessions were significantly lower in delayed two-stage placement, especially when using a nonresorbable membrane, compared to immediate placement, and labial bone thickness, measured by CBCT, offered an effectual indicator to assess gingival recession in the anterior region.

  15. Deliberations on the External Morphology and Modification of the Labial Segments in the Nepomorpha (Heteroptera: Insecta) with Notes on the Phylogenetic Characteristics

    PubMed Central

    Brożek, Jolanta

    2013-01-01

    The present study provides new data concerning the external morphology of the labial segments of 46 species from nine Nepomorpha families using the scanning electron microscope. The labial segments are described in detail and images of their structures are presented for the systematic groups. Subsequent segments of the labium (I, II, III, and IV) are shaped similarly in all investigated taxa but carry individual characters in some (sub-)families. Five morphologically distinct forms of the apical plate and five intercalary sclerites have been identified. Additionally, three types of the articulation on the dorsal side between the third and second segments are interpreted as the new characters. The presence of the midventral condyle on the distal edge of the first segment and the third segment has been reanalyzed. New position of the midventral condyle on the proximal edge of the fourth labial segment has been distinguished in several groups. The new set of characters has been estimated from the plesiomorphic taxa of the Nepoidea (Nepidae and Belostomatidae) and subsequently through the more advanced taxa in the relation to the outgroup (Gerromorpha). The evaluation of these characters has revealed twenty-seven new apomorphies for the labium in the Nepomorpha. PMID:24294137

  16. How should we treat prepubertal labial adhesions? Retrospective comparison of topical treatments: estrogen only, betamethasone only, and combination estrogen and betamethasone.

    PubMed

    Eroğlu, Egemen; Yip, Marcus; Oktar, Tayfun; Kayiran, Sinan Mahir; Mocan, Hilal

    2011-12-01

    Labial adhesion is a common finding in prepubertal girls. Traditionally, topical estrogen cream application has been the choice of conservative treatment, however, topical betamethasone treatment has also recently been employed with some success. In this retrospective study, we analysed 131 children with labial adhesions. Eleven of 71 (15.4%) patients were treated successfully with topical estrogen cream only, and 5 of 32 (15.6%) patients were treated successfully with betamethasone cream only. We successfully treated 5 of 28 (28.5%) patients with a combination of estrogen and betamethasone creams. The mean time of treatment for each regimen of therapy was 4 weeks. There was no significance between the single-therapy estrogen and single-therapy betamethasone groups (P = 1.00), between single-therapy estrogen and the combination therapy (P = .16), and the single therapy betamethasone to combination therapy (P = .35) groups. There was also no significant difference between combination estrogen and betamethasone therapy and the combined data of the single therapies (relative risk 1.85; 95% confidence interval 0.89-3.89; P =.11). For the treatment of prepubertal labial adhesions, topical estrogen and betamethasone creams were found to have similar success rates, with limited satisfactory results. The combination therapy was mildly more efficacious than each of the single therapies but was not found to be statistically significant. Surgical separation is recommended if conservative treatment fails. Copyright © 2011 North American Society for Pediatric and Adolescent Gynecology. All rights reserved.

  17. The Relationship Between the Mid-Point and Most-Prominent Point on the Labial Curve of Upper Anterior Teeth

    PubMed Central

    Smith, R.N; Brook, A.H; Karmo, M

    2009-01-01

    Objectives: This study investigates coincidence of the most-prominent point and the mid-point on upper anterior teeth in relation to the use of straight-wire appliances. Materials and Methods: Alginate impressions of the upper jaw were obtained from forty Caucasian patients. Impressions were cast using hard dental stone. The teeth on each upper study model (canine to canine) were marked along the facial axis of the clinical crown (FACC line) then separated using a very thin diamond disc. Each tooth was mounted on a glass slide using sticky wax and cut into two halves down this FACC line. Images were acquired of the sections and a straight line connecting the gingival margin and the incisal edge was drawn on the flat cut surfaces (now the proximal crosssectional view). From this line, perpendicular lines were drawn at the mid-point and most prominent point to the labial curve. Coincidence rate was calculated or whether the most prominent point was gingival or incisal to the mid-point. Results: Approximately 80% of upper central incisors had coincident mid- and most-prominent points. Upper lateral incisors and canine teeth had approximately 50% coincidence. The vast majority of cases without coincidence showed the most-prominent point incisal to the mid-point for all tooth kinds with just 5% or less gingival. Conclusions: The high proportions of non-coincident examples found suggest that clinicians should be aware of individual variation and that this may possibly effect 3rd order alignment. PMID:19672333

  18. Homeotic genes and the arthropod head: Expression patterns of the labial, proboscipedia, and Deformed genes in crustaceans and insects

    PubMed Central

    Abzhanov, Arhat; Kaufman, Thomas C.

    1999-01-01

    cDNA fragments of the homologues of the Drosophila head homeotic genes labial (lab), proboscipedia (pb), and Deformed (Dfd) have been isolated from the crustacean Porcellio scaber. Because the accumulation domains of the head homeotic complex (Hox) genes had not been previously reported for crustaceans, we studied the expression patterns of these genes in P. scaber embryos by using in situ hybridization. The P. scaber lab homologue is expressed in the developing second antennal segment and its appendages. This expression domain in crustaceans and in the homologous intercalary segment of insects suggests that the lab gene specified this metamere in the last common ancestor of these two groups. The expression domain of the P. scaber pb gene is in the posterior part of the second antennal segment. This domain, in contrast to that in insects, is colinear with the domains of other head genes in P. scaber, and it differs from the insect pb gene expression domain in the posterior mouthparts, suggesting that the insect and crustacean patterns evolved independently from a broader ancestral domain similar to that found in modern chelicerates. P. scaber Dfd is expressed in the mandibular segment and paragnaths (a pair of ventral mouthpart structures associated with the stomodeum) and differs from insects, where expression is in the mandibular and maxillary segments. Thus, like pb, Dfd shows a divergent Hox gene deployment. We conclude that homologous structures of the mandibulate head display striking differences in their underlying developmental programs related to Hox gene expression. PMID:10468590

  19. Quantification of plasma cells in labial salivary glands: increased expression of IgM in Sjögren's syndrome.

    PubMed

    Speight, P M; Cruchley, A; Williams, D M

    1990-03-01

    Plasma cells expressing IgG, IgA and IgM were quantified in labial salivary glands from patients with Sjögren's syndrome (SS) and compared with glands showing non-specific inflammatory changes and normal controls. In all glands the predominant isotype was IgA but in SS there was a significant increase in both the number and proportions of IgG and IgM positive cells (P less than 0.002). In particular, all SS cases contained greater than 10% IgM positive cells (mean = 26.8 +/- 15.5). The results suggest that accumulation of IgM positive plasma cells may be a specific finding in SS and support the concept that the glandular lesions may be a site of B-cell clonal expansion. Since most B-cell hyperproliferative states in SS, including lymphoma, are associated with synthesis of IgM simple quantification of plasma cells may have important diagnostic and prognostic significance.

  20. Labial tissue rejuvenation and sexual function improvement using a novel non-invasive focused monopolar radio frequency device.

    PubMed

    Clark, Zeljka

    2017-08-30

    With aging, the vulvar tissue loses its vitality and elasticity due to collagen fibers fatigue. Such changes and functional characteristics of the external genitalia often cause negative psychological effects resulting in impeded sexual function. The objective of this study is to evaluate the safety and efficacy of an RF device when used for treating labial laxity and for improvement of female sexual function. 19 women received 4 once-a-week treatments using a monopolar RF device. Images taken at the baseline and at the 1-month follow-up were evaluated for improvement in vulvar appearance on a scale of 0 to 3. The Female Sexual Function Index (FSFI) scores were calculated and compared between the baseline, the 1-month follow-up visit and the 12-month follow-up visit. Average improvement in the vulvar appearance according to the patients and the physician was 2.00 ± 0.58 and 1.79 ± 0.54, respectively. Both values represent 'moderate change' according to the applied scale. The average FSFI increased by 9.79 ± 4.35 and 7.10 ± 5.17 when comparing the baseline to the 1-month and the 12-month follow-up, respectively. No adverse events were reported. Efficacy and safety of the investigated device were proven. Longevity of results was proven by the 12-month follow-up.

  1. Molecular structure and spatial expression of a homeobox gene from the labial region of the Antennapedia-complex.

    PubMed Central

    Mlodzik, M; Fjose, A; Gehring, W J

    1988-01-01

    We report the molecular characterization of a homeobox-containing gene that maps at 84A in the proximal region of the Antennapedia-complex. The structure and complete sequence are presented. Deletion analysis indicates that the cloned gene, F24, most likely corresponds to the labial (lab) gene. Northern blot experiments show a single approximately 3-kb transcript that is expressed at all embryonic stages from cellular blastoderm onwards and during larval development. The homeobox is split by an intron in the region which encodes the putative DNA-binding helix, a splicing position for homeobox-containing genes which is unique so far. The 5' part of the gene contains four M-repeat sequences (CAA/G repeats) in the protein-coding region. In situ hybridization to the transcripts during embryogenesis reveals two domains of expression. The anterior one is located in parts of the developing head, mainly in the hypopharyngeal organ and in anterior parts of the mandibular lobe, and is restricted to the ectoderm. The posterior domain is part of the posterior midgut primordium (endoderm), that invaginates and later contacts the endoderm cells from the anterior midgut invagination. Images PMID:2461299

  2. Electronically monitored labial dabbing and stylet 'probing' behaviors of brown marmorated stink bug, Halyomorpha halys, in simulated environments.

    PubMed

    Wiman, Nik G; Walton, Vaughn M; Shearer, Peter W; Rondon, Silvia I

    2014-01-01

    Brown marmorated stink bug, Halyomorpha halys (Stål), (Hemiptera: Pentatomidae) is an invasive polyphagous agricultural and urban nuisance pest of Asian origin that is becoming widespread in North America and Europe. Despite the economic importance of pentatomid pests worldwide, their feeding behavior is poorly understood. Electronically monitored insect feeding (EMIF) technology is a useful tool in studies of feeding behavior of Hemiptera. Here we examined H. halys feeding behavior using an EMIF system designed for high throughput studies in environmental chambers. Our objectives were to quantify feeding activity by monitoring proboscis contacts with green beans, including labial dabbing and stylet penetration of the beans, which we collectively define as 'probes'. We examined frequency and duration of 'probes' in field-collected H. halys over 48 hours and we determined how environmental conditions could affect diel and seasonal periodicity of 'probing' activity. We found differences in 'probing' activity between months when the assays were conducted. These differences in activity may have reflected different environmental conditions, and they also coincide with what is known about the phenology of H. halys. While a substantial number of 'probes' occurred during scotophase, including some of the longest mean 'probe' durations, activity was either lower or similar to 'probing' activity levels during photophase on average. We found that temperature had a significant impact on H. halys 'probing' behavior and may influence periodicity of activity. Our data suggest that the minimal temperature at which 'probing' of H. halys occurs is between 3.5 and 6.1 °C (95% CI), and that 'probing' does not occur at temperatures above 26.5 to 29.6 °C (95% CI). We estimated that the optimal temperature for 'probing' is between 16 and 17 °C.

  3. Electronically Monitored Labial Dabbing and Stylet ‘Probing’ Behaviors of Brown Marmorated Stink Bug, Halyomorpha halys, in Simulated Environments

    PubMed Central

    Wiman, Nik G.; Walton, Vaughn M.; Shearer, Peter W.; Rondon, Silvia I.

    2014-01-01

    Brown marmorated stink bug, Halyomorpha halys (Stål), (Hemiptera: Pentatomidae) is an invasive polyphagous agricultural and urban nuisance pest of Asian origin that is becoming widespread in North America and Europe. Despite the economic importance of pentatomid pests worldwide, their feeding behavior is poorly understood. Electronically monitored insect feeding (EMIF) technology is a useful tool in studies of feeding behavior of Hemiptera. Here we examined H. halys feeding behavior using an EMIF system designed for high throughput studies in environmental chambers. Our objectives were to quantify feeding activity by monitoring proboscis contacts with green beans, including labial dabbing and stylet penetration of the beans, which we collectively define as ‘probes’. We examined frequency and duration of ‘probes’ in field-collected H. halys over 48 hours and we determined how environmental conditions could affect diel and seasonal periodicity of ‘probing’ activity. We found differences in ‘probing’ activity between months when the assays were conducted. These differences in activity may have reflected different environmental conditions, and they also coincide with what is known about the phenology of H. halys. While a substantial number of ‘probes’ occurred during scotophase, including some of the longest mean ‘probe’ durations, activity was either lower or similar to ‘probing’ activity levels during photophase on average. We found that temperature had a significant impact on H. halys ‘probing’ behavior and may influence periodicity of activity. Our data suggest that the minimal temperature at which ‘probing’ of H. halys occurs is between 3.5 and 6.1°C (95% CI), and that ‘probing’ does not occur at temperatures above 26.5 to 29.6°C (95% CI). We estimated that the optimal temperature for ‘probing’ is between 16 and 17°C. PMID:25474148

  4. Plasma cell populations in labial salivary glands from patients with and without Sjögren's syndrome.

    PubMed

    Matthews, J B; Deacon, E M; Wilson, C; Potts, A J; Hamburger, J

    1993-11-01

    Plasma cells expressing IgG, IgA and IgM were quantified in labial salivary glands from patients with Sjögren's syndrome (n = 25) and compared with glands from patients with a variety of systemic diseases (n = 32) and normal individuals (n = 15). Based on qualitative and quantitative analysis, glands from the systemic disease group were divided into normal histology (n = 24) and non-specific inflammation (n = 8) groups. There were no significant differences in cell densities or Ig class proportions between histologically normal glands from patients and those from normal volunteers. Total immunocyte densities were significantly increased in sialadenitis (P < 0.025) and Sjögren's syndrome (P < 0.001) compared with normal histology glands. In both the sialadenitis and Sjögren's syndrome groups there were significant increases in IgG and IgM cell densities (IgG, P < 0.006; IgM, P < 0.001) and proportions (IgG, P < 0.05; IgM, P < 0.001). There were no significant differences in immunocyte densities or proportions between the sialadenitis and Sjögren's syndrome groups except for a lower percentage proportion of IgA cells in the latter (P < 0.038). In all groups the total and individual Ig-class cell densities showed significant positive correlations with extent of leucocyte infiltration (P < 0.01) and negative correlations between IgA and IgG and/or IgM cell proportions. Analysis of the plasma cell data alone and in combination with quantifiable histological parameters failed to yield specific or sensitive diagnostic information. The results suggest that changes in glandular plasma cell populations in Sjögren's syndrome are non-specific.

  5. Ultrasound of the salivary glands is a strong predictor of labial gland biopsy histopathology in patients with sicca symptoms.

    PubMed

    Astorri, Elisa; Sutcliffe, Nurhan; Richards, Polly S; Suchak, Krishna; Pitzalis, Costantino; Bombardieri, Michele; Tappuni, Anwar R

    2016-07-01

    The international classification criteria for Sjögren's syndrome necessitate the presence of either extractable nuclear antibody or a characteristic focal inflammatory infiltrate in a minor salivary gland. Thus, patients who are extractable nuclear antibody-negative will need to have a labial salivary gland biopsy, which is an invasive procedure associated with morbidity. The aim of this study was to evaluate the viability of ultrasound imaging of the major salivary glands as a predictor of the histology to explore whether ultrasound can help in stratifying Sjögren's patients and reduce the need for biopsy. The records of 85 patients suspected of having Sjögren's syndrome and who have had biopsy and ultrasound were analysed retrospectively. The histology and the ultrasound were reported by experts independently. The reporting was impartial as the examiners were blinded to the results of the other investigations and to the diagnosis. Out of the 85 patients, 34 had positive ultrasound, 29 of whom also had positive histology. Fifty-one patients had negative ultrasound, of whom 49 were also negative for histological features of Sjögren's syndrome. The results show that the ultrasound had a positive predictive value of 85% and a striking negative predicative value of 96% of the histology results. The overall concordance between the ultrasound and the histology was 91% (Kappa = 0.826). Our study shows that potentially the ultrasound has a role in stratifying patients who are extractable nuclear antibody-negative and can help to prioritize the biopsy for those who have sonographic evidence of SS. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  6. Dimensional changes in height of labial alveolar bone of proclined lower incisor after lingual positioning by orthodontic treatment: A cephalometric study on adult Bengali population

    PubMed Central

    Shaw, Amit

    2015-01-01

    Aim: The study aims to know whether modern orthodontic treatment procedure do actually cause permanent bone loss at the alveolar bone crest or improve alveolar bone morphology on labial aspect of permanent incisors which are to be moved lingually. Settings and Design: Manual tracings of pre and post treatment lateral cephalometric radiographs were used. Material and Method: The cephalometric radiographs of 34 adult bengali subjects whose orthodontic treatment involved lingual positioning of procumbent mandibular central incisors were examined to determine the morphologic changes (bone height) in the labial alveolar bone that resulted from orthodontic treatment. Result: Comparison of tracings of radiographs taken before and after treatment indicated that 57.6% shows an increase in labial alveolar bone height, 30.3% shows decreased value and 12.1% shows no change with the decrease in the angulation between long axis of lower incisor and mandibular plane (GoGn). In the increase group there is a significant increase in the distance ‘incisal edge to D point’ whereas this dimension decreased significantly in the rest of the cases. In addition, a significant positive correlation (r = 0.56) was found between the changes in the distance from the incisal edge to the ‘D’ point and the alveolar bone height. But no significant relation was found between alveolar bone height and decrease in angulation of lower incisor either in the ‘increase group’ (r = 0.13, p > 0.05) or in the ‘decrease group’ (r = 0.37, p > 0.05). Conclusion: These findings indicate that during orthodontic treatment that involves lingual positioning of procumbent teeth but no intrusion, an increase in the amount of buccal alveolar bone may take place. PMID:25684908

  7. Untangle lip through Z-plasty

    PubMed Central

    Sinha, Jolly; Kumar, Vivek; Tripathi, Amitandra Kumar; Saimbi, Charanjit Singh

    2014-01-01

    An aberrant frenum causes gingival recession either due to an interference in the plaque control or due to a muscle pull. It also presents an aesthetic problem and may compromise the orthodontic result in midline diastema cases, thus causing a recurrence after the treatment. The management of such an aberrant frenum is accomplished by performing a frenectomy. The present case report shows the removal of the abnormal maxillary labial frenum in a 26-year-old male patient and an 18-year-old female patient through the Z-plasty technique. PMID:25240003

  8. Untangle lip through Z-plasty.

    PubMed

    Sinha, Jolly; Kumar, Vivek; Tripathi, Amitandra Kumar; Saimbi, Charanjit Singh

    2014-09-19

    An aberrant frenum causes gingival recession either due to an interference in the plaque control or due to a muscle pull. It also presents an aesthetic problem and may compromise the orthodontic result in midline diastema cases, thus causing a recurrence after the treatment. The management of such an aberrant frenum is accomplished by performing a frenectomy. The present case report shows the removal of the abnormal maxillary labial frenum in a 26-year-old male patient and an 18-year-old female patient through the Z-plasty technique.

  9. The role of a labial salivary gland biopsy in the diagnostic procedure for Sjögren’s syndrome; a study of 94 cases

    PubMed Central

    van Stein-Callenfels, Dewi; Tan, Jonathan; Bloemena, Elisabeth; van Vugt, Richard M.; Voskuyl, Alexandre E.; Santana, Nathalie T.Y.

    2014-01-01

    Objectives: The purpose of the present study is to examine the role of the outcome of the labial salivary gland biopsy (LSGB) in the diagnostic procedure of patients suspected of suffering from Sjögren’s syndrome (SS). Material and Methods: In a retrospective study the result of histopathological assessment of 94 consecutively taken labial salivary gland biopsies has been examined. For the diagnosis of SS the American-European Consensus Group classification (AECG, 2002) have been used. The outcome of the assessment has been discussed in relation to a recently reported classification provided by the American College of Rheumatology (ACR, 2012). Results: In the 94 LSGBs support for a diagnosis of SS has been encountered in 24 out of 26 patients with SS. In the 68 patients with a negative diagnosis of SS only six positive LSGBs were observed. The sensitivity of the labial biopsy amounted 0.92; the specificity was 0.91, while the positive predictive value and the negative predictive value amounted 0.80 and 0.97 respectively. LSGBs taken by or on the request of the departments of Rheumatology or Internal Medicine had a significant higher yield compared to LSGBs taken in other clinical departments. Conclusions: The LSGB may play a role in the diagnostic procedure of Sjögren’s syndrome when using either the AECG classification or the ACR classification. A LSGB should preferably taken after counseling for the possible presence of SS by a department of Rheumatology or Internal Medicine since the yield of such biopsies is much higher than in patients who have not been counseled by these departments prior to the taking of a LSGB. When using the ACR classification, a positive serologic result and a positive ocular test make the taking of a LSGB redundant. Only in case of a negative serologic outcome or a negative result of the ocular test a LSGB is indicated. Since both the serologic test and the ocular test carry hardly any morbidity, these tests should, indeed, be

  10. Ultrasonography of major salivary glands compared with parotid and labial gland biopsy and classification criteria in patients with clinically suspected primary Sjögren's syndrome.

    PubMed

    Mossel, Esther; Delli, Konstantina; van Nimwegen, Jolien F; Stel, Alja J; Kroese, Frans G M; Spijkervet, Fred K L; Vissink, Arjan; Arends, Suzanne; Bootsma, Hendrika

    2017-07-28

    To assess the validity of ultrasound of major salivary glands (sUS) compared with parotid and labial gland biopsies, sialometry, anti-SSA/Ro antibody status and classification criteria in patients clinically suspected with primary Sjögren's syndrome (pSS). 103 consecutive outpatients with clinically suspected pSS underwent sUS. Parenchymal echogenicity, homogeneity, hypoechogenic areas, hyperechogenic reflections and clearness of salivary gland border were scored according to the Hocevar scoring system. Total ultrasound score was calculated as the sum of these domains (range 0-48). Absolute agreement between sUS and parotid (83%) and labial (79%) gland biopsy outcome was good. Negative sUS predicts negative parotid gland biopsy, and positive sUS predicts positive labial gland biopsy. Compared with the American European Consensus Group (AECG) classification, sUS showed an absolute agreement of 82%, sensitivity of 71% and specificity of 92%. Compared with the American College of Rheumatology (ACR) classification, absolute agreement was 86%, sensitivity was 77% and specificity was 92%. Compared with the ACR-European League Against Rheumatism (EULAR) classification, absolute agreement was 80%, sensitivity was 67% and specificity was 94%. Positive sUS predicts classification, but negative sUS does not exclude classification. The combination of positive sUS with presence of anti-SSA/Ro antibodies or negative sUS with absence of anti-SSA/Ro antibodies showed a high predictive value for classification as pSS or non-pSS. In our prospective inception cohort study derived from daily clinical practice, absolute agreement between sUS and salivary gland biopsies was slightly higher for parotid compared with labial gland biopsies. The combination of positive sUS and presence of anti-SSA/Ro antibodies highly predicts classification according to the AECG, ACR and ACR-EULAR classification criteria. © Article author(s) (or their employer(s) unless otherwise stated in the text of

  11. MALT LYMPHOMA IN LABIAL SALIVARY GLAND BIOPSY FROM SJÖGREN’S SYNDROME (SS): IMPORTANCE OF FOLLOW-UP IN EARLY DETECTION

    PubMed Central

    Keszler, A; Adler, LI; Gandolfo, MS; Masquijo Bisio, PA; Smith, AC; Vollenweider, CF; Heidenreich, AM; de Stefano, G; Kambo, MV; Cox, DP; Narbaitz, M; Lanfranchi, HE

    2012-01-01

    Mucosa-associated lymphoid tissue (MALT) lymphomas are known to occur in Sjögren syndrome (SS) patients, but reported cases in labial salivary glands (LSG) are rare. We report a case of 60-year-old female patient with SS who developed MALT lymphoma in the labial salivary glands during a 2-year time interval when she was participating in the Sjögren’s International Clinical Collaborative Alliance (SICCA). SICCA is an ongoing longitudinal multisite observational study funded by the National Institutes of Health (NIH) of the United States. At follow-up exam, LSG biopsy showed atypical diffuse infiltration by mononuclear cells of variable size and atypical nuclei affecting the whole specimen with destruction of glandular architecture, leading to a diagnosis of B-cell MALT lymphoma. Computed tomography and bone marrow biopsy failed to show additional evidence of disease. Clinical, serological, ocular, histologic and immunohistochemical findings are presented. A “watch and wait” policy was adopted with regular examinations. PMID:23157989

  12. Root morphology and development of labial inversely impacted maxillary central incisors in the mixed dentition: a retrospective cone-beam computed tomography study.

    PubMed

    Sun, Hao; Wang, Yi; Sun, Chaofan; Ye, Qingsong; Dai, Weiwei; Wang, Xiuying; Xu, Qingchao; Pan, Sisi; Hu, Rongdang

    2014-12-01

    The aim of this study was to analyze 3-dimensional data of root morphology and development in labial inversely impacted maxillary central incisors. Cone-beam computed tomography images from 41 patients with impacted incisors were divided into early and late dental age groups according to their dental age. Sagittal slices in which the labiolingual width of the tooth was the widest in the axial view were evaluated. The inverse angle, the dilaceration angle, and the length of both impacted and homonym teeth were evaluated with SimPlant Pro software (version 13.0; Materialise Dental NV, Leuven, Belgium). The Student t test indicated that the lengths of the impacted teeth were significantly shorter than those of the homonym teeth (P <0.05), and the root lengths of the early dental age group were significantly shorter than those of the late dental age group. The results from chi-square tests indicated that the incidence of dilacerations was significantly higher in the late dental age group when compared with the early dental age group. Multiple regression analyses indicated that the independent variables for root length of the impacted teeth were dental age (β = 0.958; P <0.001) and length of the nondilacerated part of the root (β = 0.435; P <0.001). Dilaceration was more common in the late dental age group. The roots of labial inversely impacted maxillary central incisors continue developing, but their potential is limited. Copyright © 2014 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

  13. Growth Arrest-Specific 6 Protein in Patients with Sjögren Syndrome: Determination of the Plasma Level and Expression in the Labial Salivary Gland.

    PubMed

    Chen, Chen-Hung; Chen, Hsiang-Cheng; Chang, Chi-Ching; Peng, Yi-Jen; Lee, Chien-Hsing; Shieh, Yi-Shing; Hung, Yi-Jen; Lin, Yuh-Feng

    2015-01-01

    Growth arrest-specific protein 6 (Gas6) is a vitamin K-dependent protein expressed by endothelial cells and leukocytes that are involved in cell survival, migration, and proliferation in response to inflammatory processes. The aim of this study was to assess the implications of Gas6 in Sjögren syndrome (SS) and its expression in the labial salivary gland. A total of 254 adults, including 159 with primary Sjögren syndrome (pSS), 34 with secondary Sjögren syndrome (sSS), and 61 normal controls, were recruited. Plasma Gas6 concentrations were determined, and Gas6 expressions in labial salivary gland (LSG) tissues from controls and pSS and sSS patients were also evaluated. Plasma Gas6 concentrations were significantly lower among patients with pSS than normal controls (13.5 ± 8.6 vs. 19.9 ± 13.4 ng/ml, p < 0.001). There were, however, no significant differences in plasma Gas6 levels between pSS and sSS patients (13.5 ± 8.6 vs. 16.9 ± 11.2 ng/ml, p = 0.068). In multivariate logistic regression analysis, after adjustment for white blood cell count, hemoglobin level, platelet count, lymphocyte count, and C3 and C4 levels, lower plasma Gas6 concentrations were significantly associated with an increased risk of SS. Moreover, by using a semi-quantitative scale to evaluate Gas6 expression in LSG tissues, Gas6 expression was found to be markedly lower in LSG tissues from pSS patients than in tissues from normal controls. Decreased plasma Gas6 concentration and LSG expression were associated with pSS. As such, Gas6 may represent a novel independent risk factor for pSS, with a potential role in salivary gland inflammation and dysfunction.

  14. Absence of cytomegalovirus and Epstein-Barr virus expression in labial salivary glands of patients with chronic graft-versus-host disease.

    PubMed

    Mariette, X; Cazals-Hatem, D; Agbalika, F; Selimi, F; Brunet, M; Morinet, F; Gluckman, E

    1996-04-01

    We investigated in 15 consecutive patients a possible correlation between expression of CMV or EBV in labial salivary gland (LSG) biopsies performed 100 days after allogeneic BMT and subsequent development of chronic GVHD. Three techniques were performed for the detection of each virus: immunohistochemistry, in situ hybridization and PCR. Eleven patients developed chronic GVHD. Histologic examination detected a moderate lymphoid infiltrate (grade 1 according to Sale's score) in LSG biopsy in only one patient. CMV genes or proteins could not be detected in any patients. Likewise, EBV genome or proteins were not detected by in situ hybridization and immunohistochemistry. However, in three of the 15 patients, EBV DNA was detected by PCR in LSG biopsies. Only one of these three patients developed chronic GVHD. Therefore, at the present time, the presence of a lymphoid infiltrate on lip biopsies performed at day 100 post-BMT does not appear to be sensitive enough for the diagnosis or the prediction of the subsequent development of chronic GVHD. Moreover, the absence of EBV and CMV expression in a day-100 LSG biopsy does not preclude the development of chronic GVHD.

  15. Effect of the tongue rotation exercise training on the oral functions in normal adults - Part 1 investigation of tongue pressure and labial closure strength.

    PubMed

    Arakawa, I; Koide, K; Takahashi, M; Mizuhashi, F

    2015-06-01

    The aim of this study was to investigate the effect of the tongue rotation exercise training on the oral functions using the measurement of maximum tongue pressure (MTP) and labial closure strength (LCS) in normal adults. In experiment 1, the differences in MTP and LCS at the measurement point for both groups with and without tongue rotation exercise training were examined. We instructed subjects to perform the tongue rotation exercise for 2 months. We measured MTP and LCS at the point before training and at the points of 1 and 2 months after the beginning of training. In experiment 2, the changes of MTP and LCS based on the sex differences and the measurement points in training were examined. We instructed subjects to perform the tongue rotation exercise for 3 months, and measured MTP and LCS at the point before training and at the points of 2 weeks and 1, 2 and 3 months after the beginning of training. The results of experiment 1 showed MTP and LCS increased with the progress of continuous training. The results of experiment 2 showed MTP and LCS were always higher in men than in women and increased significantly at 2 weeks of training in both sexes (P < 0.01). These results might be suggested that the tongue rotation exercise training was effective for the recovery of the activity of the stomatognathic system.

  16. Abnormal distribution of AQP5 in labial salivary glands is associated with poor saliva secretion in patients with Sjögren's syndrome including neuromyelitis optica complicated patients.

    PubMed

    Yoshimura, Shunsuke; Nakamura, Hideki; Horai, Yoshiro; Nakajima, Hideki; Shiraishi, Hirokazu; Hayashi, Tomayoshi; Takahashi, Toshiyuki; Kawakami, Atsushi

    2016-01-01

    To investigate whether aquaporins (AQPs) are involved in salivary gland dysfunction in patients with neuromyelitis optica (NMO) complicated with Sjögren's syndrome (SS). Eight primary SS (pSS) patients, four NMO spectrum disorder (NMOsd) patients complicated with SS (NMOsd-SS), and three control subjects were enrolled. Immunohistochemistry of labial salivary glands (LSGs) was performed to determine the expressions of AQP4, AQP5, and tumor necrosis factor-alpha (TNF-α). In vitro expression of AQP5 was examined by Western blotting in cultured primary salivary gland epithelial cells (SGECs). No expression of AQP4 was shown in all LSGs. AQP5 was clearly expressed in the all acini, but the predominant localization of AQP5 in the apical side was diminished in the patients with pSS or NMOsd-SS compared with the controls and tended to be even lower in NMOsd-SS than pSS. The abnormal localization of AQP5 was associated with poor saliva secretion. No difference was found in TNF-α expression in the LSGs between patients with pSS and NMOsd-SS. AQP5 expression of SGECs in vitro was not changed by TNF-α or interleukin-10. Our results suggest that AQP5 but not AQP4 contributes to salivary secretion in patients with SS including those with NMO complicated with SS.

  17. Characteristics of primary Sjögren's syndrome patients with IgG4 positive plasma cells infiltration in the labial salivary glands.

    PubMed

    Liu, Chang; Zhang, Huayong; Yao, Genhong; Hu, Yunxia; Qi, Jingjing; Wang, Yan; Chen, Weiwei; Tang, Xiaojun; Li, Wenchao; Lu, Liwei; Gu, Luo; Sun, Lingyun

    2017-01-01

    The purpose of this study was to investigate the characteristics of primary Sjögren's syndrome (pSS) patients with IgG4 positive (IgG4(+)) plasma cell infiltration in labial salivary glands (LSGs). Paraffin sections of LSGs from 336 pSS patients were stained with IgG4 and IgG monoclonal antibodies. According to the infiltration of IgG4(+) plasma cells, patients were divided and clinical and serological characteristics were analyzed and compared. Based on the infiltration of IgG4(+) plasma cells in the LSGs, patients were divided into three subgroups, low IgG4, moderate IgG4, and high IgG4 groups. A negative association between the number of infiltrated IgG4(+) plasma cells and the disease characteristics was observed. We found that the higher the IgG4(+) expression in plasma cells, the lower the positive rates of serum anti-SSA antibodies, anti-SSB antibodies, antinuclear antibodies (ANA), and rheumatoid factor (RF). Besides, patients from the high IgG4 group had the highest frequency of interstitial lung disease (ILD, 30.6%) and tubulointerstitial nephritis (TIN, 13.9%), but the lowest frequency of leucopenia (13.9%), thrombocytopenia (11.1%), and abnormal thyroidal function (0%). PSS patients with different IgG4(+) plasma cells infiltration in the LSGs had distinctive clinical and laboratory characteristics. It may help us to further understand the role of IgG4(+) plasma cells in pSS.

  18. Stereotypic rheumatoid factors that are frequently expressed in mucosa-associated lymphoid tissue-type lymphomas are rare in the labial salivary glands of patients with Sjögren's syndrome.

    PubMed

    Bende, Richard J; Slot, Linda M; Hoogeboom, Robbert; Wormhoudt, Thera A M; Adeoye, Akanbi O; Guikema, Jeroen E J; van Noesel, Carel J M

    2015-04-01

    Among autoimmune diseases, Sjögren's syndrome (SS) is most strongly associated with the development of malignant B cell lymphoma, in particular mucosa-associated lymphoid tissue (MALT)-type lymphoma. Previously, we have shown that in ∼40% of cases of salivary gland MALT lymphoma, high-affinity stereotypic rheumatoid factor (RF) B cell receptors, specific for IgG-Fc, are expressed. This study was undertaken to investigate whether in the inflamed salivary glands of patients with SS, a similar RF-biased Ig repertoire is present. Extensive analyses of the B cell Ig VH region repertoire were performed on microdissected tissue samples from the labial salivary glands of 4 patients with SS. All SS labial salivary glands harbored expanded B cell clones, of which 1 or 2 were highly expanded and detected in >50% of the microdissected samples. However, among the identified 464 distinct Ig clonotypes, only 3 stereotypic RF-expressing clones were detected. In 2 patients with SS, an RF-expressing clone was detected at low frequency in 1 of the microdissected samples, whereas 1 patient with SS harbored a highly expanded RF-expressing clone that was detected in all microdissected samples and also detected in the peripheral blood. Two years after analysis of this sample, the latter patient developed a diffuse large B cell lymphoma originating from the same RF clone. Inflamed labial salivary glands in patients with SS generally harbor 1 or 2 highly expanded B cell clones. The repertoire strongly biased toward stereotypic RFs in salivary gland MALT lymphomas is not a reflection of a similar repertoire in the inflamed salivary glands of patients with SS; rather, in the latter, the repertoire is based on a strong selection advantage of incidental stereotypic RF-expressing B cells. Copyright © 2015 by the American College of Rheumatology.

  19. Treatment of relapse in herpes simplex on labial and facial areas and of primary herpes simplex on genital areas and "area pudenda" with low-power He-Ne laser or Acyclovir administered orally

    NASA Astrophysics Data System (ADS)

    Velez-Gonzalez, Mariano; Urrea-Arbelaez, Alejandro; Nicolas, M.; Serra-Baldrich, E.; Perez, J. L.; Pavesi, M.; Camarasa, J. M.; Trelles, Mario A.

    1996-01-01

    Sixty patients (greater than 16 yrs old) suffering primary or relapse genital herpes simplex viruses (HSV) and relapse labial HSV were appointed for this study. Three or more relapses were experienced per year. Patients (under treatment) were divided into two groups (distribution areas), corresponding to either labial herpes or genital herpes. These groups were sub-divided into 3 groups. The total number of labial or facial HSV patients was 36 (10 in group 1, 12 in group 2, 14 in group 3) and 24 for genital, buttocks, or 'area pudenda' HSV patients (6 in group 1, 8 in group 2, 10 in group 3). The design was a randomized, double- blind study. The setting was hospital and outpatient. The patients diagnosed as having the HVS disease were sent to the dermatology department and were assigned to a group at random. Treatment was begun as follows: During the treatment signs and symptoms were assessed and after the treatment, the relapses were also assessed (biochemical and hematological tests before and after the treatment) and the diagnosis of the HSV type I and II. The statistical evaluation of the results was performed and carried out with the SPSS and BMDP program. The relapses of the herpes infection in the lips and the face were significantly reduced (p less than 0.026) in patients treated with laser He-Ne and laser He-Ne plus Acyclovir. The interim between the relapses also increased significantly (p less than 0.005) in relation with the group treated with Acyclovir. The duration of the herpetic eruptions was clearly reduced in all locations in patients treated with laser He-Ne plus Acyclovir. No differences were noted between patients treated with laser He-Ne only or Acyclovir only. Therefore it is probable that therapeutic synergism took place. In relation with this, laser He-Ne shows the same therapeutic efficacy as Acyclovir taken orally. The association of Acyclovir and laser Ne-Ne could be an alternative method for the treatment of HSV in the face. The number

  20. A Case of Incontinentia Pigmenti Associated with Multiorgan Abnormalities

    PubMed Central

    Chung, Woon-Kyong; Lee, Deok-Woo; Chang, Sung-Eun; Lee, Mi-Woo; Choi, Jee-Ho

    2009-01-01

    Incontinentia pigmenti is a systemic disorder affecting the skin, teeth, eyes, nervous tissue, hair, nails, musculoskeletal system, and heart. We describe an 11-month-old girl with incontinentia pigmenti associated with a ventricular septal defect, left hemiatrophy, hemangiomas, an abnormal labial frenum, and spastic cerebral palsy manifested as left hemiplegia and developmental delay. We believe this patient illustrates that incontinentia pigmenti is a systemic disorder necessitating a multidisciplinary approach to management. PMID:20548858

  1. Inverted mesiodens--a case report.

    PubMed

    Nikhil, S; Vineeta; Gupta, P

    1999-09-01

    A nine and a half years old female school child was examined in a during routine dental examination. The patient had swelling over maxillary midline area just near the labial frenum. Both the central incisors were in position. Radiographic examination revealed presence of an inverted supernumerary tooth between the roots of the central incisors. Surgical extraction of the supernumerary was planned. A unique case of inverted (upside down) mesiodens is presented.

  2. Paralleling technique for frenectomy and oral hygiene evaluation after frenectomy.

    PubMed

    Abullais, Shahabe Saquib; Dani, Nitin; Ningappa, Priyanka; Golvankar, Kapil; Chavan, Amit; Malgaonkar, Nikhil; Gore, Anup

    2016-01-01

    High frenum attachment is a very common problem in the population. Various conventional techniques are available which has certain disadvantages; in addition to that high frenum also hinders oral hygiene maintenance. This study aims to evaluate patient's response to two different frenectomy technique, and oral hygiene maintenance before and after frenectomy. Twenty patients with high labial frenum were randomly selected from the outpatient department. Patients were divided into two groups according to the technique used. Each group contained ten patients. One group was treated by "conventional scalpel technique" and other group by "new paralleling technique". To evaluate patients response, visual analogue scale for pain and speech were taken at first postoperative day, 1-week and 1-month. In other part of the study the oral hygiene maintenance was evaluated by using plaque and gingival bleeding index at baseline before frenectomy, 1-week and 1-month after frenectomy. Results showed that new paralleling technique for frenectomy causes less postoperative discomfort and also there was significant improvement in the oral hygiene maintenance by the patient after frenectomy. High maxillary frenum causes hindrance in oral hygiene maintenance. Paralleling technique for frenectomy causes less discomfort to the patient during healing phase when compared with the conventional technique.

  3. Paralleling technique for frenectomy and oral hygiene evaluation after frenectomy

    PubMed Central

    Abullais, Shahabe Saquib; Dani, Nitin; Ningappa, Priyanka; Golvankar, Kapil; Chavan, Amit; Malgaonkar, Nikhil; Gore, Anup

    2016-01-01

    Background: High frenum attachment is a very common problem in the population. Various conventional techniques are available which has certain disadvantages; in addition to that high frenum also hinders oral hygiene maintenance. This study aims to evaluate patient's response to two different frenectomy technique, and oral hygiene maintenance before and after frenectomy. Materials and Methods: Twenty patients with high labial frenum were randomly selected from the outpatient department. Patients were divided into two groups according to the technique used. Each group contained ten patients. One group was treated by “conventional scalpel technique” and other group by “new paralleling technique”. To evaluate patients response, visual analogue scale for pain and speech were taken at first postoperative day, 1-week and 1-month. In other part of the study the oral hygiene maintenance was evaluated by using plaque and gingival bleeding index at baseline before frenectomy, 1-week and 1-month after frenectomy. Results: Results showed that new paralleling technique for frenectomy causes less postoperative discomfort and also there was significant improvement in the oral hygiene maintenance by the patient after frenectomy. Conclusion: High maxillary frenum causes hindrance in oral hygiene maintenance. Paralleling technique for frenectomy causes less discomfort to the patient during healing phase when compared with the conventional technique. PMID:27041834

  4. [Labial commissures. Reconstructive procedures and indications].

    PubMed

    Simon, E; Stricker, M; Duroure, F

    2002-10-01

    The commisures are the two extremities of the mouth. They make a big complex in their architecture and their function. Their repairing should have an important attention to their final shape and function. The frequency of the retraction of the scarring tissue imposes additional muscular exercise which has to be premature, intense, and prolonged.

  5. Labial Adhesions: A Guide for Parents

    MedlinePlus

    ... Apply the estrogen cream sparingly. Too much estrogen cream can cause an “estrogen effect” such as darkening of the vulvar skin, breast buds, and rarely vaginal bleeding. Symptoms resolve after the treatment is ... if the (estrogen) cream is working? Over time small openings will appear ...

  6. Modified lip repositioning: A surgical approach to treat the gummy smile.

    PubMed

    Rao, Aditya Gopinath; Koganti, Vijay Prasad; Prabhakar, Ashok Kodangala; Soni, Sweta

    2015-01-01

    Gummy smile has been an esthetic concern for many patients. This clinical report describes a successful surgical coverage obtained by modified lip repositioning, thus surgically treating the gummy smile. The technique was performed to limit the retraction of elevator muscles (e.g., zygomaticus minor, orbicularis oris, leviator anguli oris and levator labi oris.) The technique is fulfilled by removing two strips of mucosa from maxillary buccal vestibule on both the sides leaving the frenum untouched and creating a partial thickness flap between mucogingival junction and upper lip musculature, and suturing the lip mucosa with mucogingival junction, resulting in a narrow vestibule and restricted muscle pull, thereby reducing gingival display. This technique is different from the conventional surgical lip repositioning as labial frenum is left untouched over here as it helps in maintain Litton the midline for lip repositioning and reduces the morbidity associated with it.

  7. Modified lip repositioning: A surgical approach to treat the gummy smile

    PubMed Central

    Rao, Aditya Gopinath; Koganti, Vijay Prasad; Prabhakar, Ashok Kodangala; Soni, Sweta

    2015-01-01

    Gummy smile has been an esthetic concern for many patients. This clinical report describes a successful surgical coverage obtained by modified lip repositioning, thus surgically treating the gummy smile. The technique was performed to limit the retraction of elevator muscles (e.g., zygomaticus minor, orbicularis oris, leviator anguli oris and levator labi oris.) The technique is fulfilled by removing two strips of mucosa from maxillary buccal vestibule on both the sides leaving the frenum untouched and creating a partial thickness flap between mucogingival junction and upper lip musculature, and suturing the lip mucosa with mucogingival junction, resulting in a narrow vestibule and restricted muscle pull, thereby reducing gingival display. This technique is different from the conventional surgical lip repositioning as labial frenum is left untouched over here as it helps in maintain Litton the midline for lip repositioning and reduces the morbidity associated with it. PMID:26229285

  8. Early creeping attachment after frenectomy: a case report.

    PubMed

    Fowler, E B; Breault, L G

    2000-01-01

    An abnormal labial frenutomy is capable of causing retraction of gingival margins, formation of diastema and inhibition of lip and tongue movements. When aberrant frenula are present traditional frenectomy procedures are very successful. Often mucogingival procedures are needed to correct the defects that result from harmful frenum pulls. In this case presentation, an aberrant frenum was diagnosed to be associated with an area of recession on a mandibular left central incisor. Surgery was planned as a staged approach. The first phase of care was a simple frenectomy. A follow-on procedure consisting of a connective tissue graft for root coverage was planned. After only four weeks of healing from the frenectomy, creeping attachment of 1.0 mm was appreciated and the patient was able to avoid the secondary corrective surgery.

  9. Development and application of a perioral force measurement system for infants with cleft lip and palate.

    PubMed

    Zhang, Lixian; Zheng, Yaqi; Rong, Qiong; Wu, Guofeng

    2017-07-03

    Muscles converge or intertweave around the perioral area, and this can be treated with sequential therapy in infants with cleft lip and palate (CLP). The force of perioral muscles has a great influence on maxillary development and morphology. Perioral force in infants with CLP has not been well studied, and accurate and reliable measurement of perioral force in infants remains a challenge. This study aimed to investigate a new way to accurately and reliably measure perioral force in infants with unilateral CLP (UCLP) and explore the change before and after cheiloplasty. A perioral force measurement system was developed and applied to measure perioral force at labial frenum area and the commissures on both the normal and the cleft sides of four infants with UCLP before and after cheiloplasty. The results were analyzed using the SPSS 19.0 software. The perioral force measurement system appears to produce valid results in infants with UCLP. Before cheiloplasty, the perioral force of labial frenum area was 1.79 ± 0.94 g/cm(2) and that of commissure on the normal and cleft sides was 5.41 ± 1.01 g/cm(2) and 3.12 ± 1.55 g/cm(2), respectively (P < 0.05). After cheiloplasty, perioral force of labial frenum area was 12.73 ± 3.51 g/cm(2) and that of commissure on the normal and cleft sides was 7.64 ± 1.64 g/cm(2) and 7.27 ± 1.89 g/cm(2), respectively (P > 0.05). Copyright © 2017 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

  10. The angiographic tension test in mucogingival surgery.

    PubMed

    Gaberthüel, T W; Mörmann, W

    1978-08-01

    Attached gingiva's integrity was studied with the aid of fluorescein angiography and a standardized frenal tension test in 15 subjects aged between 19 and 41 years (9 female, 6 male) with mucogingival pathology in the region of the mandibular labial frenum. Each subject showed preoperatively gingival angiographic ischemia under 200 p frenal traction. The angiographic ischemia was in no case congruent to the clinical ischemia. One month after surgical enlargement of attached gingiva (eight grafts of palatal mucosa, seven subperiosteal vestibulum extension) both mucogingival surgery techniques successfully prevented the gingival blood circulation from showing ischemia clinically as well as angiographically under 200 p frenal traction.

  11. Vestibular Extension along with Frenectomy in Management of Localized Gingival Recession in Pediatric Patient: A New Innovative Surgical Approach.

    PubMed

    Jingarwar, Mahesh; Pathak, Anuradha; Bajwa, Navroop Kaur; Kalaskar, Ritesh

    2015-01-01

    This paper reports case of pediatric localized gingival recession (LGR) in mandibular anterior region which was treated by using new innovative surgical approach, i.e. combination of frenectomy and vestibular extension. These interceptive surgeries not only gained sufficient width of attached gingival but also lower the attachment of labial frenum. How to cite this article: Jingarwar M, Pathak A, Bajwa NK, Kalaskar R. Vestibular Extension along with Frenectomy in Management of Localized Gingival Recession in Pediatric Patient: A New Innovative Surgical Approach. Int J Clin Pediatr Dent 2015;8(3):224-226.

  12. Vestibular Extension along with Frenectomy in Management of Localized Gingival Recession in Pediatric Patient: A New Innovative Surgical Approach

    PubMed Central

    Pathak, Anuradha; Bajwa, Navroop Kaur; Kalaskar, Ritesh

    2015-01-01

    ABSTRACT This paper reports case of pediatric localized gingival recession (LGR) in mandibular anterior region which was treated by using new innovative surgical approach, i.e. combination of frenectomy and vestibular extension. These interceptive surgeries not only gained sufficient width of attached gingival but also lower the attachment of labial frenum. How to cite this article: Jingarwar M, Pathak A, Bajwa NK, Kalaskar R. Vestibular Extension along with Frenectomy in Management of Localized Gingival Recession in Pediatric Patient: A New Innovative Surgical Approach. Int J Clin Pediatr Dent 2015;8(3):224-226. PMID:26604542

  13. Multifocal canalicular adenoma of the minor labial salivary glands

    PubMed Central

    Samar, María Elena; Avila, Rodolfo Esteban; Fonseca, Ismael Bernardo; Anderson, William; Fonseca, Gabriel M; Cantín, Mario

    2014-01-01

    Canalicular adenoma (CA) is an uncommon benign neoplasia of salivary glands which is clinically difficult to recognise. Despite having an excellent prognosis, the histological diagnosis and clinical management of this entity can be troublesome. While the main differential diagnosis to consider is basal cell adenoma (BCA), similar histological patterns and multifocality have been observed in adenoid cystic carcinoma (ACC) and polymorphous low-grade adenocarcinoma (PLGA), both locally-aggressive malignancies which require radically different treatment to CA. An emphasis has been placed on the value of immunohistochemistry in avoiding diagnostic and surgical errors. CA is positive for AE1/AE3, CD117 and S-100 protein, and negative for p63, α-SMA, Ki 67 and vimentin. Here we discuss the case of a 61-year-old female with CA in her right upper lip, showing multifocal growth histologically. The differential diagnosis with other adenomas is discussed in addition to the role of immunohistochemical studies that can confirm the clinical and surgical findings. PMID:25550873

  14. A laterality effect in isometric and isotonic labial tracking.

    PubMed

    Sussman, H M; Westbury, J R

    1978-09-01

    Hemispheric dominance for sensorimotor control of lip activity was investigated by use of a pursuit auditory tracking task. This task involves continuous frequency matching of a computer-generated target tone and a subject-controlled cursor tone. Thirty right-handed subjects were tested under isometric lip and hand control, and 20 right-handed subjects under isotonic lip control. Subjects tracked 10 1-min trials under each laterality condition--cursor/right ear, target/left ear, and vice versa. In both experiments tracking performance was better when the lip-controlled cursor tone was presented to the right ear (hence direct contralateral route to left hemisphere). A significant (p less than 0.05) cursor/right-ear advantage was found under isometric hand-tracking. Analysis routines examined relative laterality advantages across several time intervals within each 1-min trial. Consistent lateralization scores in favor of cursor/right-ear presentations (REAs) were independent of the time interval measured. For isometric tracking, 58% of subjects having laterality advantages (p less than 0.10) revealed REAs. For isotonic tracking, 71% of subjects revealed REAs. Implications of the latter finding are discussed relative to a left hemisphere mechanism specialized to integrate movement-generated auditory feedback with dynamic kinesthetic information from the articulators.

  15. An extraordinary case of syphilis presenting with a labial ulcer

    PubMed Central

    Demir, Filiz T.; Salaeva, Kenyul; Altunay, Ilknur K.; Yalcın, Ozben

    2016-01-01

    In the differential diagnosis of patients with ulcers on the lips characteristics like the duration of the ulcer, number, size, depth, shape, base, margins, and distribution are considered. Such ulcers arise from many diseases particularly, viral and bacterial infections, malignancies can also be responsible. Classic syphilitic chancres are painless erosions settled on hard papule; these are evident in the genital area in more than 90% of patients. This study describes a case of a 38-year-old female patient presenting with a painful ulcer covering 3 quarters of the upper lip showing settlement on erythematous, edematous, and indurated plaque covered with hemorrhagic crusts. The aim of this study was to consider differences between the classic syphilitic chancre typically found in the genital region from extragenital chancres and to raise awareness of the possibility of primary syphilis when patients present with painful ulcers on the lip. PMID:27761567

  16. Articulatory control of phonological vowel length contrasts: kinematic analysis of labial gestures.

    PubMed

    Hertrich, I; Ackermann, H

    1997-07-01

    The present study investigated the articulatory control of the German vowel quantity contrast, i.e., the phonological difference between short and long vowels. By means of an optoelectronic system the excursions of the compound lower lip/jaw opening and closing gestures were measured during production of test sentences comprising the target sequence /pVp/ (V = /a/, /i/, /u/, /a:/, /i:/, /u:/). First, a highly linear relationship between peak velocity and movement amplitude emerged within each quantity class. Second, vowel quantity systematically influenced the scaling of velocity and amplitude during oral opening. Third, as compared to their short counterparts, long vowels showed an increased peakedness of the velocity profile. Finally, the velocity profiles of the long vowels were characterized by an asymmetric shape in terms of a prolonged deceleration phase of the opening and a lengthened acceleration interval of the closing movement. With respect to durational coarticulation patterns, the control of vowel quantity clearly differed from intrinsic, i.e., vowel type-induced, variability. The latter was partially compensated for the level of word duration by shortening of the prevocalic consonant whereas vowel quantity turned out to be primarily due to the lengthening of the syllable /pV/.

  17. Compensation for Complete Assimilation in Speech Perception: The Case of Korean Labial-to-Velar Assimilation

    ERIC Educational Resources Information Center

    Mitterer, Holger; Kim, Sahyang; Cho, Taehong

    2013-01-01

    In connected speech, phonological assimilation to neighboring words can lead to pronunciation variants (e.g., "garden bench" [arrow right] "garde'm' bench"). A large body of literature suggests that listeners use the phonetic context to reconstruct the intended word for assimilation types that often lead to incomplete assimilations (e.g., a…

  18. Degradation of labial information modifies audiovisual speech perception in cochlear-implanted children.

    PubMed

    Huyse, Aurélie; Berthommier, Frédéric; Leybaert, Jacqueline

    2013-01-01

    The aim of the present study was to examine audiovisual speech integration in cochlear-implanted children and in normally hearing children exposed to degraded auditory stimuli. Previous studies have shown that speech perception in cochlear-implanted users is biased toward the visual modality when audition and vision provide conflicting information. Our main question was whether an experimentally designed degradation of the visual speech cue would increase the importance of audition in the response pattern. The impact of auditory proficiency was also investigated. A group of 31 children with cochlear implants and a group of 31 normally hearing children matched for chronological age were recruited. All children with cochlear implants had profound congenital deafness and had used their implants for at least 2 years. Participants had to perform an /aCa/ consonant-identification task in which stimuli were presented randomly in three conditions: auditory only, visual only, and audiovisual (congruent and incongruent McGurk stimuli). In half of the experiment, the visual speech cue was normal; in the other half (visual reduction) a degraded visual signal was presented, aimed at preventing lipreading of good quality. The normally hearing children received a spectrally reduced speech signal (simulating the input delivered by the cochlear implant). First, performance in visual-only and in congruent audiovisual modalities were decreased, showing that the visual reduction technique used here was efficient at degrading lipreading. Second, in the incongruent audiovisual trials, visual reduction led to a major increase in the number of auditory based responses in both groups. Differences between proficient and nonproficient children were found in both groups, with nonproficient children's responses being more visual and less auditory than those of proficient children. Further analysis revealed that differences between visually clear and visually reduced conditions and between groups were not only because of differences in unisensory perception but also because of differences in the process of audiovisual integration per se. Visual reduction led to an increase in the weight of audition, even in cochlear-implanted children, whose perception is generally dominated by vision. This result suggests that the natural bias in favor of vision is not immutable. Audiovisual speech integration partly depends on the experimental situation, which modulates the informational content of the sensory channels and the weight that is awarded to each of them. Consequently, participants, whether deaf with cochlear implants or having normal hearing, not only base their perception on the most reliable modality but also award it an additional weight.

  19. An Evaluation of the Marginal Sharpness of the Porcelain Labial Margin Metal Ceramic Restoration

    DTIC Science & Technology

    1991-05-01

    permanent molar in each case and constructed 12 crowns, one each for 12 patients, which they checked annually for three years. The gingival index of...the gingival attachment complex. He observed that frequently a healthy sulcus will probe less than one millimeter. In such cases , a restoration should...in many cases the cement film thickness at the defective margin was greater than 200 micrometers. This degree of marginal opening provided an ideal

  20. Improved communication with the laboratory for the fabrication of labial veneers.

    PubMed

    Schwartzman, Aaron; Zweig, Alan E

    2015-04-01

    Advances in dental materials and adhesive technologies have changed the way we practice dentistry. Consequently, restorative dentistry has seen the adoption and almost exponential increase in usage of materials like zirconia and lithium disilicate. Unlike the incidence of ceramic failure in the past, these newer materials are paving the road to better looking dentistry. This paper focuses on lithium disilicate and predominantly glassy ceramics, as well as improving communication with the laboratory.

  1. Secondary reconstruction of vaginal stenosis using a posterior labial perforator based Falandry flap

    PubMed Central

    Slaoui, Amine; Bagayogo, Tidiani Kariba; Karmouni, Tarik; Elkhader, khalid; Koutani, Abdelatif; Attaya, Ahmed Ibn

    2015-01-01

    The aim of vaginoplasty should be the creation without excessive morbidity of a neovagina that will be satisfying in appearance, function and feeling. The multitude of methods described in the literature indicates the fact that an ideal approach has not yet been found. In this paper the authors describe the technique for repairing vaginal stenosis by interposing between the vaginal walls, a skin flap pedicled removed using the Falandry technique at a high lip. We achieved a satisfactory result. PMID:27375830

  2. Adult patients' adjustability to orthodontic appliances. Part I: a comparison between Labial, Lingual, and Invisalign™.

    PubMed

    Shalish, Miri; Cooper-Kazaz, Rena; Ivgi, Inbal; Canetti, Laura; Tsur, Boaz; Bachar, Eytan; Chaushu, Stella

    2012-12-01

    This prospective study examined the adult patient's perception of recovery after insertion of three types of orthodontic appliances: Buccal, Lingual and Invisalign. The sample consisted of sixty-eight adult patients (45 females and 23 males) who comprised three groups: 28 Buccal, 19 Lingual, and 21 Invisalign patients. After appliance insertion, patients completed a Health-Related Quality of Life questionnaire daily for the first week and again on day 14, in order to assess patients' perception of pain and analgesic consumption. In addition, four areas of dysfunction were assessed: oral dysfunction, eating disturbances, general activity parameters, and oral symptoms. Lingual appliance was associated with more severe pain and analgesic consumption, the greatest oral and general dysfunction, and the most difficult and longest recovery. The Invisalign patients complained of relatively high levels of pain in the first days after insertion; however this group was characterized by the lowest level of oral symptoms and by a similar level of general activity disturbances and oral dysfunction compared to the Buccal appliance. Many Lingual and some Buccal patients did not reach a full recovery from their eating difficulties by the end of the study period. The present study provides information to adult patients and clinicians assisting them in choosing the most appropriate treatment modality in relation to Health-Related Quality of Life parameters.

  3. Severe Edema After Sclerotherapy of Labial Hemangioma With Ethamolin Oleate in a Young Child.

    PubMed

    de Queiroz, Sormani Bento Fernandes; de Lima, Valthierre Nunes; Amorim, Pedro Henrique Gonçalves Holanda; Statkievicz, Cristian; Magro-Filho, Osvaldo

    2016-09-01

    Adverse reactions related to ethanolamine oleate (EO) include pain during injection, redness, inflammation, tissue necrosis, and allergic reaction. The authors report a patient of exuberant facial edema after the injection of EO used in sclerotherapy of lip hemangioma in a child. A 9-year-old boy was referred to authors' oral and maxillofacial surgery unit to treat a vascular lesion of the upper lip. The lesion has causing enlargement of the middle area of the upper lip, being sessile and resilient by palpation. It was decided to employ sclerotherapy aiming to reduce the size for posterior surgical excision of the residual lesion. The day after the injection, the patient presented intense edema limited to the upper lip, complaining of mild pain. Although side effects reported of EO injection are mild and with almost no clinical significance, major complications like anaphylaxis and severe edema can occur, such in the patient here presented.

  4. [Sequels of labial-alveolar-velopalatine clefts observed in charity missions. Analysis and management].

    PubMed

    Saboye, J; Chancholle, A-R

    2007-09-01

    A lot of children with cleft lip and palate are not operated in the developing world, due to a lack of surgeons, hospitals, or simply because the condition is not considered as a priority. Charity missions give the opportunity to repair these malformations. Non-operated cleft lip and palate are the first problem, but our surgery may cause growth disturbances and sometimes a second operation is needed, more difficult than the first one in mission conditions. Repairing a cleft palate needs to be adapted to the type of cleft but also to the age of the child, a velopalatine pharyngoplasty can be performed in some cases.

  5. Floor of the nose mucosa lysis and labial abscess caused by a bee sting.

    PubMed

    Alemán Navas, Ramón Manuel; Martínez Mendoza, María Guadalupe; Herrera, Henry; Herrera, Helen Piccolo de

    2009-01-01

    Hymenoptera order includes bees, which have a stinging apparatus at the tail capable of delivering venom to the affected tissues. Myocardial infarction, acute renal failure, Necrotizing fasciitis, fatal infection and hemifacial asymmetry, are some of the unusual reactions reported following hymenoptera stings. This paper reports a case of bee sting in the right floor of the nose that mimicked an odontogenic infection affecting the upper lip, canine space and nasal cavity such as in cases of infection secondary to pulpal or periodontal pathology of the anterior teeth. After a thorough clinical and radiographic examination, odontogenic infection was discarded and the diagnosis of floor of the nose mucosal lysis and lip abscess secondary to a bee sting was made. This case was successfully managed with adequate incision, drainage and antibiotics without any further complication. There are several reports of unusual reactions following hymenoptera stings. However, just a few of them referred to infections of local reactions and none of them related to the anatomic location affected in the patient of the present case. Early diagnosis and treatment prevented infection dissemination and the likelihood of tissue necrosis as in previously reported cases of Necrotizing fasciitis.

  6. Compensation for Complete Assimilation in Speech Perception: The Case of Korean Labial-to-Velar Assimilation

    ERIC Educational Resources Information Center

    Mitterer, Holger; Kim, Sahyang; Cho, Taehong

    2013-01-01

    In connected speech, phonological assimilation to neighboring words can lead to pronunciation variants (e.g., "garden bench" [arrow right] "garde'm' bench"). A large body of literature suggests that listeners use the phonetic context to reconstruct the intended word for assimilation types that often lead to incomplete assimilations (e.g., a…

  7. Patient Presentation and Management of Labial Ulceration Following Uterine Artery Embolization

    SciTech Connect

    Gonsalves, Carin Franciosa, Stefan V.; Shah, Suken; Bonn, Joseph; Wu, Christine

    2007-11-15

    Uterine artery embolization is a safe and effective procedure for the treatment of symptomatic uterine fibroids. Nontarget embolization of adjacent internal iliac artery branches is a reported complication of uterine artery embolization. The following report describes the presentation and management of ulcerations of the labium minora due to nontarget embolization of the internal pudendal artery.

  8. Changes in labial capillary density on ascent to and descent from high altitude.

    PubMed

    Gilbert-Kawai, Edward; Coppel, Jonny; Phillip, Hennis; Grocott, Michael; Ince, Can; Martin, Daniel

    2016-01-01

    Present knowledge of how the microcirculation is altered by prolonged exposure to hypoxia at high altitude is incomplete and modification of existing analytical techniques may improve our knowledge considerably. We set out to use a novel simplified method of measuring in vivo capillary density during an expedition to high altitude using a CytoCam incident dark field imaging video-microscope. The simplified method of data capture involved recording one-second images of the mucosal surface of the inner lip to reveal data about microvasculature density in ten individuals. This was done on ascent to, and descent from, high altitude. Analysis was conducted offline by two independent investigators blinded to the participant identity, testing conditions and the imaging site.  Additionally we monitored haemoglobin concentration and haematocrit data to see if we could support or refute mechanisms of altered density relating to vessel recruitment. Repeated sets of paired values were compared using Kruskall Wallis Analysis of Variance tests, whilst comparisons of values between sites was by related samples Wilcoxon Signed Rank Test. Correlation between different variables was performed using Spearman's rank correlation coefficient, and concordance between analysing investigators using intra-class correlation coefficient. There was a significant increase in capillary density from London on ascent to high altitude; median capillaries per field of view area increased from 22.8 to 25.3 (p=0.021). There was a further increase in vessel density during the six weeks spent at altitude (25.3 to 32.5, p=0.017). Moreover, vessel density remained high on descent to Kathmandu (31.0 capillaries per field of view area), despite a significant decrease in haemoglobin concentration and haematocrit. Using a simplified technique, we have demonstrated an increase in capillary density on early and sustained exposure to hypobaric hypoxia at thigh altitude, and that this remains elevated on descent to normoxia. The technique is simple, reliable and reproducible.

  9. Changes in labial capillary density on ascent to and descent from high altitude

    PubMed Central

    Gilbert-Kawai, Edward; Coppel, Jonny; Phillip, Hennis; Grocott, Michael; Ince, Can; Martin, Daniel

    2016-01-01

    Present knowledge of how the microcirculation is altered by prolonged exposure to hypoxia at high altitude is incomplete and modification of existing analytical techniques may improve our knowledge considerably. We set out to use a novel simplified method of measuring in vivo capillary density during an expedition to high altitude using a CytoCam incident dark field imaging video-microscope. The simplified method of data capture involved recording one-second images of the mucosal surface of the inner lip to reveal data about microvasculature density in ten individuals. This was done on ascent to, and descent from, high altitude. Analysis was conducted offline by two independent investigators blinded to the participant identity, testing conditions and the imaging site.  Additionally we monitored haemoglobin concentration and haematocrit data to see if we could support or refute mechanisms of altered density relating to vessel recruitment. Repeated sets of paired values were compared using Kruskall Wallis Analysis of Variance tests, whilst comparisons of values between sites was by related samples Wilcoxon Signed Rank Test. Correlation between different variables was performed using Spearman’s rank correlation coefficient, and concordance between analysing investigators using intra-class correlation coefficient. There was a significant increase in capillary density from London on ascent to high altitude; median capillaries per field of view area increased from 22.8 to 25.3 (p=0.021). There was a further increase in vessel density during the six weeks spent at altitude (25.3 to 32.5, p=0.017). Moreover, vessel density remained high on descent to Kathmandu (31.0 capillaries per field of view area), despite a significant decrease in haemoglobin concentration and haematocrit. Using a simplified technique, we have demonstrated an increase in capillary density on early and sustained exposure to hypobaric hypoxia at thigh altitude, and that this remains elevated on descent to normoxia. The technique is simple, reliable and reproducible. PMID:27746908

  10. Maxillomandibular relationship in TMD patients before and after short-term flat plane bite plate therapy.

    PubMed

    Fu, Alexander S; Mehta, Noshir R; Forgione, Albert G; Al-Badawi, Emad A; Zawawi, Khalid H

    2003-07-01

    This study assessed the maxillomandibular relationship in temporomandibular disorders (TMD) patients, before and after short-term, flat plane bite plate therapy. It was of interest to determine the incidence and degree of mandibular deviation in a group of TMD patients and whether the mandible would shift to the midline and consequently affect reported symptoms. Seventeen female and three male subjects (age range 19-60) were included in the study. Thirteen subjects were diagnosed with myofascial pain while seven were diagnosed as exhibiting disk displacement with reduction (Research Diagnostic Criteria). After taking impressions for these subjects, casts were fabricated and mounted. Maxillomandibular relationship was evaluated by the Denar Centric Check system (Anaheim, CA). The maxillary and mandibular labial frena were used as a reference to evaluate mandibular shift. Symptom questionnaires were used to assess temporomandibular joint pain and clicking. All subjects exhibited deviation (12 subjects to the right and 8 subjects to the left) prior to bite plate therapy. After flat plane bite plate therapy, the mandibular position of all subjects shifted toward the labial frenum midline position. Based on the Binomial test, the shift was significant (p < 0.001). Measurements on the Centric Check system showed a significant movement of both condyles in the anterio-posterior plane as well as the vertical plane. There was also significant reduction in TMJ pain and clicking (p < 0.01). The results support the hypothesis that the balanced position of the mandible is with frena aligned. When occlusal obstructions are eliminated, the mandible will drift to this position.

  11. Clinical manifestations and oral findings in Fraser syndrome.

    PubMed

    Diniz, Michele Baffi; Lima, Luciana Monti; Sacono, Nancy Tomoko; de Paula, Andréia Bolzan; dos Santos-Pinto, Lourdes

    2007-01-01

    This article is the first known case report of Fraser syndrome in the dental literature. Its purpose was to present the clinical manifestations, oral findings, and dental treatment of a 14-year, 10-month-old female patient. Fraser syndrome is a rare recessive autosomal genetic disorder characterized by multisystemic malformation, usually comprising cryptophthalmos, syndactyly, and renal defects. The child presented with: (1) hydrocephaly; (2) face asymmetry; (3) low-inserted ears; (4) flat nose bridge; (5) cryptophthalmos; (6) bilateral absence of eyeballs; (7) hypertelorism; (8) syndactyly on the left fingers and toes; (9) skeletal defects; and (10) lower limb asymmetry. The intraoral examination revealed: (1) complete primary denture; (2) malocclusion; (3) tooth crowding; (4) ogival palate; (5) normal labial frena; (6) absence of lingual frenum (not compromising the tongue movements); (7) parched lips; (8) supragingival calculus adhered to all tooth surfaces; and (9) moderate gingivitis. The dental treatment consisted of periodic monitoring of the patient's oral health status and supragingival scaling associated with topical applications of 0.12% chlorhexidine digluconate gel at 2-week intervals to reduce gingivitis.

  12. Revisiting the Factors Underlying Maxillary Midline Diastema.

    PubMed

    Jaija, Abdullah M Zakria; El-Beialy, Amr Ragab; Mostafa, Yehya A

    2016-01-01

    Aim. The aim of this study is to analyze the etiological factors underlying the presence of maxillary midline diastema in a sample of orthodontic patients. Materials and Methods. One hundred patients who fulfill the inclusion criteria were selected from 1355 patients seeking orthodontic treatment. The pretreatment orthodontic records were analyzed. The width of the maxillary midline diastema was measured clinically with a digital caliper at two levels: the mesioincisal angles of the central incisors and five millimeters from the incisal edge. The two measurements were averaged, and patients with diastema of more than 0.5 millimeter in width were enrolled. Results. Diastema is a multifactorial clinical finding with more than one underlying etiological cause. The interrelationship between the familial pattern of midline diastema and the microdontia, macroglossia, labial frenum, and alveolar cleft conforms was clear. The effect of a mesiodens and the upper lateral incisor whether bilaterally missing, unerupted, or peg shaped was minimal. Conclusion. Etiological factors underlying maxillary midline diastema are interconnected. Using a checklist as a guide during handling maxillary midline diastema is important in the different stages of treatment.

  13. Revisiting the Factors Underlying Maxillary Midline Diastema

    PubMed Central

    Jaija, Abdullah M. Zakria; El-Beialy, Amr Ragab; Mostafa, Yehya A.

    2016-01-01

    Aim. The aim of this study is to analyze the etiological factors underlying the presence of maxillary midline diastema in a sample of orthodontic patients. Materials and Methods. One hundred patients who fulfill the inclusion criteria were selected from 1355 patients seeking orthodontic treatment. The pretreatment orthodontic records were analyzed. The width of the maxillary midline diastema was measured clinically with a digital caliper at two levels: the mesioincisal angles of the central incisors and five millimeters from the incisal edge. The two measurements were averaged, and patients with diastema of more than 0.5 millimeter in width were enrolled. Results. Diastema is a multifactorial clinical finding with more than one underlying etiological cause. The interrelationship between the familial pattern of midline diastema and the microdontia, macroglossia, labial frenum, and alveolar cleft conforms was clear. The effect of a mesiodens and the upper lateral incisor whether bilaterally missing, unerupted, or peg shaped was minimal. Conclusion. Etiological factors underlying maxillary midline diastema are interconnected. Using a checklist as a guide during handling maxillary midline diastema is important in the different stages of treatment. PMID:27239374

  14. [A functional approach in the primary treatment of labial-alveolar-velopalatine clefts for a minimum of sequels].

    PubMed

    Talmant, J-C; Talmant, J-Ch; Lumineau, J-P

    2007-09-01

    Is the poor potential of growth an ineluctable consequence of mesodermal deficiency? Should we agree with the idea that all protocols are equivalent? Actually, these opinions reflect the empiricism of previous generations. We must now become rational and develop a project without compromise to achieve good functions at primary surgery. 'The normal structures are present on either side of the cleft, only modified by the fact of the cleft...' Victor Veau's hypothesis is the conclusion of rigorous anatomical and embryological research. Our current knowledge of the pathological anatomy allows for a better restoration of the normal anatomy. Anatomy is nothing if it is not functional. Every thing should be done to control the healing process to allow the best expression and interaction of the various functions, especially for those concerning nasal ventilation and masticatory efficiency. To correct the deformity, the cleft surgeon must perform a wide subperiosteal and subperichondrial elevation and must learn the skills of this accurate work to preserve the integrity of very fragile structures. The primary treatment must take into account a rational and uncompromising selection of the age of the first operation, of the successive procedures, and their chronology to benefit from the growth spurt of the maxilla, and to avoid the worse scars resulting from secondary epithelialization. Finally, if nasal breathing is the most important function concerning facial growth, it is essential to restore this normal function at the time of the first operation. The oral breathing pattern set at the time of the first operation leaves a cortical imprint that is very difficult to erase, even after clearing the nasal airways. The results of the functional approach we have used in the last decade are particularly consistent and very convincing. In this ambitious and demanding program, the patient comes first; we decrease the burden for him and his family, and give them the benefit of a good social life before school age.

  15. [Variety of cows and sires according to types of dermatoglyphics (patterns) of the nose-labial mirror of cattle].

    PubMed

    Trofimenko, A L

    1988-01-01

    Dermatoglyphic+ of the nasal-lip speculum presents a complex structure of skin picture on its surface. Genetics and phenetics of this character permit determining different types of dermatoglyphics, their hereditary peculiarities to be retained in generations. Different types of dermatoglyphics are established to be preserved within genealogical lines and families of cows. Differences between breeds in some dermatoglyphic elements are observed.

  16. Analysis of nasal and labial deformities in cleft lip, alveolus and palate patients by a new rating scale: preliminary report.

    PubMed

    Anastassov, Y; Chipkov, C

    2003-10-01

    In this study the nasal deformities in patients with cleft lip, alveolus and palate (CLAP) were analysed and the relevant role of the perinasal-perioral muscular balance, and the inborn dislocation of the alar cartilages is presented. 50 CLAP patients were analysed in whom 29 primary cheiloplasties, 12 lip revisions and 9 rhinoplasties were performed. The lip repair was done by a modification of Millard's technique, the nose by either a closed or open-sky rhinoplasty. The severity of the cleft appearance was evaluated pre- and postoperatively, according to a pre-agreed visual rating scale. There were 4 degrees of severity of the deformity preoperatively (mild, moderate, severe and very severe), and postoperatively 5 categories of outcome (excellent, very good, good, satisfactory and poor) depending on the scores obtained by summing up the points corresponding to different types of deformity. This scale is closely related to the American Cleft Palate classification of clefts. 17 excellent, 4 very good, 2 good, 5 satisfactory and 1 poor result were obtained in the group of primary cheiloplasty. Eight excellent, 4 very good results were obtained by the lip revisions. Seven excellent and 2 satisfactory results were obtained following rhinoplasty. During the primary lip repair, it is important to correct the abnormal position of ala nasi, the nasal floor and the base of the columella. When correct insertion of m. transversus nasi to the nasal spine is achieved and a good repair of m. orbicularis oris, symmetry of the alae and normal growth of lip and columella was obtained even in most severe bilateral cases. In cases of diastasis of the orbicularis and transversus nasi muscles, in combination with other soft tissue deformities or scars, a secondary musculo-periosteal revision is recommended. The defect of the soft tissue triangle of the nose is best corrected via an open rhinoplasty.

  17. Dynamical account of how /b, d, g/ differ from /p, t, k/ in Spanish: Evidence from labials

    PubMed Central

    PARRELL, BENJAMIN

    2013-01-01

    This study examines articulatory lenition of intervocalic stops in Spanish and tests the theories that 1) /b, d, g/ have an intended target for closure equal to that of /p, t, k/ and 2) spirantization of /b, d, g/ is caused by undershoot due to their short duration phrase medially. Consistent with past acoustic studies, subjects produce /b/ with incomplete closure phrase medially and complete closure phrase initially. Additionally, /b/ is shorter than /p/ phrase medially though not initially. For /b/, though not for /p/, there is a correlation between constriction degree and duration, consistent with the theory of dynamical undershoot. The results from the study are accurately modeled with a virtual target for /b/ slightly beyond the point of articulator contact. Such a target results in full closure at long durations (such as found phrase initially) and incomplete closure at shorter durations. Based on this evidence, it is proposed that /b, d, g/ differ from /p, t, k/ in three ways: they are shorter, lack a devoicing gesture, and have a target closer to – but still beyond – the point of articulator contact. PMID:23843928

  18. [Frenectomy associated with a triangular gingival graft].

    PubMed

    Borghetti, A; Guy, J P; Cesano, B

    1991-11-01

    In periodontal therapy, frenectomy is indicated when the frenum exerts tension on the gingival margin and interferes with proper oral hygiene. The procedure is also employed when the frenum prevents closure of a diastema during orthodontic therapy. Frenectomy should be done after the canines have erupted and before retention is started to prevent separation of the teeth. For an improved surgical and cosmetic result, the authors propose a triangular-shaped gingival graft after the frenum has been excised. The advantage of the procedure is to create an area of attached gingiva and enhance healing.

  19. Simultaneous occurrence of multiple melanoma in situ on sun-damaged skin (lentigo maligna), solar lentigo and labial melanosis: the value of dermoscopy in diagnosis.

    PubMed

    Massi, D; Nardini, P; De Giorgi, V; Carli, P

    1999-11-01

    We report on a patient developing simultaneous occurrence of lentigo maligna lesions, solar lentigines and an extensive melanosis of the oral mucosa. Diagnostically, epiluminescence microscopy had a relevant role in the preoperative assessment and selection of suspicious pigmented lesions, as the lesions histologically labelled as lentigo maligna and solar lentigo were clinically indistinguishable. We review the clinical, dermoscopic and histopathologic differential diagnosis of solar lentigo, malignant lentigo and mucosal melanosis with other melanocytic and keratinocytic lesions and discuss the possible relationship between these entities.

  20. Detection of HTLV-1 in the labial salivary glands of patients with Sjögren’s syndrome: a distinct clinical subgroup?

    PubMed

    Lee, Sung-Ji; Lee, Ji Shin; Shin, Myung-Geun; Tanaka, Yuetsu; Park, Dong-Jin; Kim, Tae-Jong; Park, Yong-Wook; Lee, Shin-Seok

    2012-04-01

    To examine whether patients with Sjögren's syndrome (SS) can be distinguished based on the expression of human T cell lymphotrophic virus type I (HTLV-1) and, if so, whether the subgroups differ in their clinical features and serological measures. Polymerase chain reaction (PCR) and nested PCR were used to amplify viral DNA from peripheral blood mononuclear cells (PBMC) in 53 patients with SS, using primers from the HTLV-1 pX, p19, pol, and tax regions. Minor salivary gland biopsy specimens from 33 patients with SS were examined for the presence of HTLV-1 p19 or tax proteins immunohistochemically. The sociodemographic, glandular, and extraglandular manifestations, and laboratory findings including autoantibodies, complement, and immunoglobulin levels, were analyzed. The HTLV-1 tax gene was detected in PBMC samples from 2 of 53 patients (3.8%), whereas the HTLV-1 pX, p19, and pol genes were not expressed. As well, 100% of PBMC samples from 4 family members of patients in whom the tax gene was detected also expressed the tax gene. Immunohistochemical staining for HTLV-1 p19 and tax was seen in 10 out of 33 (30.3%) patients with SS each. Overall, 14 (42.4%) patients expressed HTLV-1 p19 or tax proteins, and they had lower rheumatoid factor and C3 levels (p = 0.015 and p = 0.005, respectively) and higher lymphocyte counts (p = 0.016). The prevalence of glandular and extraglandular manifestations did not differ between the HTLV-1-positive and negative patients. Our findings suggest that HTLV-1 in the salivary glands is involved in the pathogenesis of a subpopulation of SS, and HTLV-1-associated SS might have different immunological patterns than idiopathic SS.

  1. Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 8. Assessing naso-labial appearance in 5-year-olds - a preliminary study.

    PubMed

    Mølsted, Kirsten; Humerinta, Kirsti; Küseler, Annelise; Skaare, Pål; Bellardie, Haydn; Shaw, William; Karsten, Agneta; Kåre Sæle, Paul; Rizell, Sara; Marcusson, Agneta; Eyres, Philip; Semb, Gunvor

    2017-02-01

    Facial appearance is one of the most relevant measures of success in cleft lip and palate treatment. The aim was to assess nasolabial appearance at 5 years of age in all children in the project. In this part of the project the local protocol for lip closure continued to be used because the primary lip and nose operations were not part of the randomisation. The great majority of the surgeons used Millard's technique together with McComb's technique for the nose. One center used Tennison-Randalls technique and in one center the centers own technique as well as nose plugs were used. Three hundred and fifty-nine children participated in this part of the project. Standardised photos according to a specific protocol developed for the Scandcleft project were taken. Only the nasolabial area was shown, the surrounding facial features were masked. Three components were scored using a 5-point ordinal scale. A new developed Scandcleft Yardstick was used. The reliability of the method was tested using the weighted kappa statistics. Both the interrater and intrarater reliability scores were good to very good. There were statistically significant differences between the three trials. The Millard procedure combined with McComb technique had been used in the majority of the cases in all three trials. There were statistically significant differences between the three trials concerning upper lip, nasal form, and cleft side profile. ISRCTN29932826.

  2. Frenectomy: a review with the reports of surgical techniques.

    PubMed

    Devishree; Gujjari, Sheela Kumar; Shubhashini, P V

    2012-11-01

    The frenum is a mucous membrane fold that attaches the lip and the cheek to the alveolar mucosa, the gingiva, and the underlying periosteum. The frena may jeopardize the gingival health when they are attached too closely to the gingival margin, either due to an interference in the plaque control or due to a muscle pull. In addition to this, the maxillary frenum may present aesthetic problems or compromise the orthodontic result in the midline diastema cases, thus causing a recurrence after the treatment. The management of such an aberrant frenum is accomplished by performing a frenectomy.The present article is a compilation of a brief overview about the frenum, with a focus on the indications, contraindications, advantages and the disadvantages of various frenectomy techniques, like Miller's technique, V-Y plasty, Z-plasty and frenectomy by using electrocautery. A series of clinical cases of frenectomy which were approached by various techniques have also been reported.

  3. Frenectomy: A Review with the Reports of Surgical Techniques

    PubMed Central

    Devishree; Gujjari, Sheela Kumar; Shubhashini, P.V.

    2012-01-01

    The frenum is a mucous membrane fold that attaches the lip and the cheek to the alveolar mucosa, the gingiva, and the underlying periosteum. The frena may jeopardize the gingival health when they are attached too closely to the gingival margin, either due to an interference in the plaque control or due to a muscle pull. In addition to this, the maxillary frenum may present aesthetic problems or compromise the orthodontic result in the midline diastema cases, thus causing a recurrence after the treatment. The management of such an aberrant frenum is accomplished by performing a frenectomy. The present article is a compilation of a brief overview about the frenum, with a focus on the indications, contraindications, advantages and the disadvantages of various frenectomy techniques, like Miller's technique, V-Y plasty, Z-plasty and frenectomy by using electrocautery. A series of clinical cases of frenectomy which were approached by various techniques have also been reported. PMID:23285469

  4. Assessment of Lingual Frenulum Lengths in Skeletal Malocclusion

    PubMed Central

    Meenakshi, Swarna; Jagannathan, Nithya

    2014-01-01

    Background: The orofacial musculature plays a pivotal role in maintaining a balance in positioning of the teeth and any imbalance which occurs in this , results in malocclusion. Lingual frenum is a soft tissue structure which tethers the ventral surface of the tongue to the floor of the mouth. Objective: This study was performed to analyze the lingual frenal lengths in skeletal class I, class II and Class III malocclusion and to correlate relationship between both. Materials and Methods: This study comprised of 30 subjects, with 10 in each group and an impression was made with the maximum mouth opening position and the tip of tongue touching the incisive papilla. The length of the lingual frenum was then measured from the casts. The maximum mouth opening position was also determined by measuring the interincisal distance with the maximum mouth opening position. Statistical analysis was done to analyze the relationship between both. Results: The lingual frenum was found to be longest in class III malocclusion, with a statistical significant value of p<0.01. The class II and class I malocclusion did not show much difference. The maximum mouth opening position was also increased in class III malocclusion, followed by class II and class I malocclusion, in a descending order. Conclusion: The lingual frenum exerts erratic forces and a long lingual frenum pushes the mandibular anteriors forwards, resulting in malocclusion. Hence, a relationship between the lingual frenum and malocclusion is essential, so that the erratic forces can be eliminated and excellent results can be achieved, following the correction of malocclusion. PMID:24783137

  5. An overview of frenal attachments

    PubMed Central

    Priyanka, M.; Sruthi, R.; Ramakrishnan, T.; Emmadi, Pamela; Ambalavanan, N.

    2013-01-01

    Frenal attachments are thin folds of mucous membrane with enclosed muscle fibers that attach the lips to the alveolar mucosa and underlying periosteum. Most often, during the oral examination of the patient the dentist gives very little importance to the frenum, for assessing its morpholology and attachment. However, it has been seen that an abnormal frenum can be an indicator of a syndrome. This paper highlights the different frenal attachments seen in association with various syndromic as well as non-syndromic conditions. PMID:23633765

  6. Contour of lingual surface in lower complete denture formed by polished surface impression.

    PubMed

    Heo, Yu-Ri; Kim, Hee-Jung; Son, Mee-Kyoung; Chung, Chae-Heon

    2016-12-01

    The aim of this study was to analyze the shapes of lingual polished surfaces in lower complete dentures formed by polished surface impressions and to provide reference data for use when manufacturing edentulous trays and lower complete dentures. Twenty-six patients with mandibular edentulism were studied. After lower wax dentures were fabricated, wax was removed from the lingual side of the wax denture and a lingual polished surface impression was obtained with tissue conditioner. The definitive denture was scanned with a three-dimensional scanner, and scanned images were obtained. At the cross-sections of the lingual frenum, lateral incisors, first premolars, first molars, and anterior border of the retromolar pads, three points were marked and eight measurements were taken. The Kruskal-Wallis test and a post hoc analysis with the Mann-Whitney test were performed. Each patient showed similar values for the same areas on the left and right sides without a statistically significant difference. The height of the contour of the lingual polished surface at the lingual frenum was halfway between the occlusal plane and lingual border, it moved gradually in a downward direction. The angle from the occlusal plane to the height of the contour of the lingual polished surface was increased as it progressed from the lingual frenum towards the retromolar pads. The shape of the mandibular lingual polished surface was convex at the lingual frenum, lateral incisors and gradually flattened towards the first molars and retromolar pads.

  7. Contour of lingual surface in lower complete denture formed by polished surface impression

    PubMed Central

    2016-01-01

    PURPOSE The aim of this study was to analyze the shapes of lingual polished surfaces in lower complete dentures formed by polished surface impressions and to provide reference data for use when manufacturing edentulous trays and lower complete dentures. MATERIALS AND METHODS Twenty-six patients with mandibular edentulism were studied. After lower wax dentures were fabricated, wax was removed from the lingual side of the wax denture and a lingual polished surface impression was obtained with tissue conditioner. The definitive denture was scanned with a three-dimensional scanner, and scanned images were obtained. At the cross-sections of the lingual frenum, lateral incisors, first premolars, first molars, and anterior border of the retromolar pads, three points were marked and eight measurements were taken. The Kruskal-Wallis test and a post hoc analysis with the Mann-Whitney test were performed. RESULTS Each patient showed similar values for the same areas on the left and right sides without a statistically significant difference. The height of the contour of the lingual polished surface at the lingual frenum was halfway between the occlusal plane and lingual border, it moved gradually in a downward direction. The angle from the occlusal plane to the height of the contour of the lingual polished surface was increased as it progressed from the lingual frenum towards the retromolar pads. CONCLUSION The shape of the mandibular lingual polished surface was convex at the lingual frenum, lateral incisors and gradually flattened towards the first molars and retromolar pads. PMID:28018565

  8. Prevalence and Speech Production Characteristics of Ankyloglossia in Preschool Children.

    ERIC Educational Resources Information Center

    Nisenboum, Jean M.; And Others

    The study investigated the prevalence and associated problems of ankyloglossia, characterized by restricted movement of the tongue usually due to the adhesion of the tongue to the frenum, among a preschool Head Start population (N=1,440). Ss were screened for six primary characteristics of the condition and of the 78 children who exhibited the…

  9. Prevalence and Speech Production Characteristics of Ankyloglossia in Preschool Children.

    ERIC Educational Resources Information Center

    Nisenboum, Jean M.; And Others

    The study investigated the prevalence and associated problems of ankyloglossia, characterized by restricted movement of the tongue usually due to the adhesion of the tongue to the frenum, among a preschool Head Start population (N=1,440). Ss were screened for six primary characteristics of the condition and of the 78 children who exhibited the…

  10. Arterial anatomy of the lower lip: a cadaveric study.

    PubMed

    Edizer, Mete; Mağden, Orhan; Tayfur, Volkan; Kiray, Amaç; Ergür, Ipek; Atabey, Atay

    2003-06-01

    The aim of the study was to investigate the arterial anatomy of the lower lip. The location, course, length, and diameter of the inferior labial artery and the sublabial artery were revealed by bilateral meticulous anatomic dissections in 14 adult male preserved cadaver heads. Another cadaver head was used for silicone rubber injection to fill the regional arterial tree. The inferior labial artery was the main artery of the lower lip and in all cases branched off the facial artery. The mean length of the inferior labial artery was found to be 52.3 mm (range, 16 to 98 mm). The mean distance of the origin of the inferior labial artery from the labial commissura was 23.9 mm. The mean external diameter of the inferior labial artery at the origin was 1.2 mm. The sublabial artery was present in 10 (71 percent) of the cadavers. Mean measurements of this artery were 1 mm for diameter, 23.4 mm for length, and 27.6 mm for distance from the labial commissura. The sublabial artery may originate from the facial artery or the inferior labial artery. This study found that this region does not have a constant arterial distribution, the inferior labial artery and the sublabial artery (if it exists) can be in different locations unilaterally or bilaterally, and the diameter and the length may vary.

  11. Effect of different labio-lingual spaces in tray designs on the displacement of and pressure against a mobile tooth.

    PubMed

    Nishi, Y; Tsuru, K; Kishita, C; Kamashita, Y; Hamano, T; Nagaoka, E

    2008-09-01

    The present study aimed to examine the effect of custom tray designs on the displacement of mobile tooth and local impression pressures during the impression procedure, using partially edentulous simulation models with six anterior teeth containing a mobile tooth prepared in previous studies. The custom trays were designed by altering the thickness of the respective spaces on the labial and lingual sides of the remaining tooth arch. In previous studies, the mobile tooth was displaced in the labial direction and local impression pressures of the mobile tooth were greater against the lingual side than the labial side for all custom tray designs. Furthermore, the custom trays perforated with holes on the lingual side were effective to reduce mobile tooth displacement, labial and lingual impression pressures against the mobile tooth, and the differences between them. Therefore, the present study was performed focusing on the labial and lingual thickness of spaces in custom tray designs. It was found that mobile tooth displacement, labial and lingual impression pressures against the mobile teeth and their differences were less in trays with spaces>3.0 mm thick on both the labial and lingual sides, but markedly greater in trays with a 1.5 mm-thick space on the labial side. These results indicate that the thickness of spaces on the labial side in the tray should not be reduced to prevent mobile tooth displacement.

  12. Perio-esthetic surgery: Using LPF with frenectomy for prevention of scar.

    PubMed

    Chaubey, K Krishna; Arora, Vipin K; Thakur, Rajesh; Narula, Inderpreet S

    2011-07-01

    An aberrant frenum is postulated to create functional and aesthetic problems. Archer's 'classical frenectomy' is an extensive procedure including the excision of fibers, interdental papilla, and exposure of alveolar bone up to the palatine papilla. The resultant delayed healing, loss of interdental papilla, and abnormal scar led towards the conservative approaches like Edward's frenectomy, frenum relocation by Z-plasty and free gingival graft; with their technical and aesthetic limitations. A better approach to make a primary closure in midline and to avoid anesthetic scar by creating a zone of attached gingiva, frenectomy is assisted with lateral pedicle graft. The interdental papilla is left surgically undisturbed and healing takes place by primary intention. Miller, in his study on 27 subjects, suggested that the newly created zone of attached gingiva might have bracing effect inhibiting reopening of diastema. A case series of this technique with its distinct advantages is presented.

  13. Er, Cr:YSGG laser for the treatment of ankyloglossia

    PubMed Central

    Lamba, Arundeep K.; Aggarwal, Kamal; Faraz, Farrukh; Tandon, Shruti; Chawla, Kirti

    2015-01-01

    Ankyloglossia or tongue-tie is the result of a short and tight lingual frenum causing difficulty in speech, feeding problems in infants due to the limitation of tongue movement. This report presents a case of a 22-year-old female with tongue-tie who complained of difficulty in speech following which she underwent frenectomy procedure with erbium, chromium: yattrium-scandium-gallium-garnet laser without any complications. She was referred to the speech therapist after the procedure. PMID:26392733

  14. Er, Cr:YSGG laser for the treatment of ankyloglossia.

    PubMed

    Lamba, Arundeep K; Aggarwal, Kamal; Faraz, Farrukh; Tandon, Shruti; Chawla, Kirti

    2015-01-01

    Ankyloglossia or tongue-tie is the result of a short and tight lingual frenum causing difficulty in speech, feeding problems in infants due to the limitation of tongue movement. This report presents a case of a 22-year-old female with tongue-tie who complained of difficulty in speech following which she underwent frenectomy procedure with erbium, chromium: yattrium-scandium-gallium-garnet laser without any complications. She was referred to the speech therapist after the procedure.

  15. Relapse after orthodontic correction of maxillary median diastema: a follow-up evaluation of consecutive cases.

    PubMed

    Shashua, D; Artun, J

    1999-06-01

    An evaluation of 96 treated orthodontic patients with maxillary median diastema ranging from 0.50 mm to 5.62 mm (mean 1.22, SD 0.85) was performed 4.0 to 9.0 years after completion of active treatment. Pre- and posttreatment data were gathered from available records. Follow-up data were gathered from records and interviews of 37 patients, and from phone interviews of 59 patients. The incidence of diastema relapse was 49% when scored as either presence of a measurable space at follow-up, a history of orthodontic or prosthetic retreatment to close a reopened space, or continued use of a retainer to control relapse tendency. Logistic regression analysis revealed that pretreatment diastema size and presence of a family member with a similar condition were the only significant risk factors for relapse (p<0.05), while pretreatment spacing in the maxillary anterior dentition approached significance (p = 0.10). No association was found between relapse and presence of an abnormal frenum or an osseous intermaxillary cleft, although patients with an abnormal frenum had a wider pretreatment diastema than those with a normal frenum (p<0.05). Fremitus of the maxillary incisors was the only parameter at follow-up associated with space reopening (p<0.01).

  16. Pseudocromata, a new genus of Ochlerini based on a new species from Ecuador (Discocephalinae: Pentatomidae)

    USDA-ARS?s Scientific Manuscript database

    In addition to the carinate metasternum, in Cromata the labrum equals the length of the first labial segment, whereas in Pseudocromata the labrum equals the length of the first two labial segments. The males of Pseudocromata do not have the dorsal process extending from the 7th abdominal tergite fou...

  17. The acoustics of uvulars in Tlingit

    NASA Astrophysics Data System (ADS)

    Denzer-King, Ryan E.

    This paper looks at the acoustics of uvulars in Tlingit, an Athabaskan language spoken in Alaska and Canada. Data from five native speakers was used for acoustic analysis for tokens from five phoneme groups (alveolars, plain velars, labialized velars, plain uvulars, and labialized uvulars). The tokens were analyzed by computing spectral moments of plosive bursts and fricatives, and F2 and F3 values for post-consonantal vowels, which were used to calculate locus equations, a descriptive measure of the relationship between F2 at vowel onset and midpoint. Several trends were observed, including a greater difference between F2 and F 3 after uvulars than after velars, as well as a higher center of gravity (COG) and lower skew and kurtosis for uvulars than for velars. The comparison of plain versus labialized consonants supports the finding of Suh (2008) that labialization lowers mean burst energy, or COG, and additionally found labialization to raise skew and kurtosis.

  18. Cone beam computed tomographic analyses of alveolar bone anatomy at the maxillary anterior region in Chinese adults

    PubMed Central

    Zhou, Zhixuan; Chen, Wu; Shen, Ming; Sun, Chao; Li, Jun; Chen, Ning

    2014-01-01

    To provide an anatomical basis for clinical implant esthetics, we evaluated the morphology of the nasopalatine canal (NPC) and analyzed labial and interproximal bone anatomy at the maxillary anterior region. We sought to investigate the effect of maxillary protrusion and tooth labiolingual inclination on labial bone anatomy in Chinese adults. Three dimensional (3D) images were reconstructed using cone-beam computed tomography (CBCT) images from 80 Chinese subjects and by SimPlant 11.04. The dimensions of the NPC, the thickness and profile of the labial bone, the width and height of the interproximal bone, angle sella-nasion-subspinale (SNA) and angle upper central incisor-nasion,subspinale (U1-NA) were measured. The incisive foramen of the NPC was markedly wider than its nasal foramen. The dimension of its labial bone wall demonstrated an increasing width from the crestal to apical measurements. The labial bone at the maxillary anterior region was rather thin, especially at 3 mm below the cemento-enamel junction (CEJ) and the mid-root level; the profile of the labial bone was more curved at the central incisor, and the interproximal bone became wider and shorter posteriorly. There were significant relationships between maxillary protrusion and labial bone profile, tooth labiolingual inclination and labial bone thickness (P < 0.02). To achieve optimal esthetic outcome of implant, bone augmentation is necessary at the maxillary anterior region. For immediate or early placement at the maxillary anterior region, the implant should be located palatally to reduce labial bone resorption and marginal recession; its apex should be angulated palatally to avoid labial perforation at the apical region. To protect the NPC, implants at the central incisor region should be placed away from NPC. PMID:25469120

  19. Effect of labiolingual inclination of a maxillary central incisor and surrounding alveolar bone loss on periodontal stress: A finite element analysis

    PubMed Central

    Choi, Sung-Hwan; Kim, Young-Hoon; Lee, Kee-Joon

    2016-01-01

    Objective The aim of this study was to investigate whether labial tooth inclination and alveolar bone loss affect the moment per unit of force (Mt/F) in controlled tipping and consequent stresses on the periodontal ligament (PDL). Methods Three-dimensional models (n = 20) of maxillary central incisors were created with different labial inclinations (5°, 10°, 15°, and 20°) and different amounts of alveolar bone loss (0, 2, 4, and 6 mm). The Mt/F necessary for controlled tipping (Mt/Fcont) and the principal stresses on the PDL were calculated for each model separately in a finite element analysis. Results As labial inclination increased, Mt/Fcont and the length of the moment arm decreased. In contrast, increased alveolar bone loss caused increases in Mt/Fcont and the length of the moment arm. When Mt/F was near Mt/Fcont, increases in Mt/F caused compressive stresses to move from a predominantly labial apical region to a palatal apical position, and tensile stresses in the labial area moved from a cervical position to a mid-root position. Although controlled tipping was applied to the incisors, increases in alveolar bone loss and labial tooth inclination caused increases in maximum compressive and tensile stresses at the root apices. Conclusions Increases in alveolar bone loss and labial tooth inclination caused increases in stresses that might cause root resorption at the root apex, despite the application of controlled tipping to the incisors. PMID:27226961

  20. A novel single-stage procedure for increasing the width of attached gingiva and eliminating the aberrant frenal attachment.

    PubMed

    Kumar, Santhosh; Suresh P, Gautham; Anand, K Meena

    2015-03-01

    Common treatment for buccal gingival recession caused by an aberrant frenal attachment includes elimination of the frenum and treatment of the gingival recession by soft tissue graft to increase the width of the attached gingiva that in turn results in root coverage. Keratinised gingival, if present in adequate amount, maintains the gingival health by protecting the marginal gingiva. This not only considers the desires of the patient but also explores the potential regenerative capacity of the tissues. This report describes a novel single-stage procedure for increasing the width of the attached gingiva and eliminating the aberrant frenal attachment.

  1. [Excerpts from the eulogy of Jean-Louis Petit presented during the public session of the Royal Academy of Surgery on May 26 1750 by A. Louis].

    PubMed

    Louis, A

    2001-06-01

    Jean-Louis Petit (1674-1750) was first enthusiastic about anatomy, received a master's certificate in surgery in Paris in 1700, became a member of the Royal Academy of Sciences in 1715, and was named director of the Royal Academy of Surgery by the king when it was created in 1731. He acquired great notoriety because of his skill and experience, thanks to his case reports of hemorrhage, lacrimal fistula, operation on the frenum, for his treatise on bone diseases and especially for his general treatise on surgical operations on which he worked 12 years and which was finished after his death by F.D. Lesne.

  2. Correcting the frenal pull and increasing the width of keratinized mucosa around endosseous implants using denudation procedure.

    PubMed

    Park, Jun-Beom

    2008-01-01

    The frenum exerts a pull upon the tissue and can lead to the continuation of the lesion, and the keratinized tissue provides increased resistance to the periodontium. Various techniques have been used to deepen the vestibule and increase the keratinized mucosa. However, there is no case report on correcting the frenal pull and increasing the keratinized mucosa around dental implant using denudation procedure. This article presents a case of frenal pull that was corrected with denudation procedure with the incision line within the keratinized tissue.

  3. Early lingual frenectomy assisted by CO2 laser helps prevention and treatment of functional alterations caused by ankyloglossia.

    PubMed

    Fiorotti, Renata C; Bertolini, Milene M; Nicola, Jorge H; Nicola, Ester M D

    2004-11-01

    Incorrectly produced speech sounds, the presence of dentofacial alterations and acquired functional adaptations may be due to a short and inadequate lingual frenum. When frenectomy is indicated, it should be performed as early as possible to prevent functional alterations. This study presents a literature review on correct lingual positioning in relation to orthodontic and phonetic function as well as an assessment of 15 patients who underwent frenectomy utilizing the carbon dioxide laser. The results demonstrated that this technique is safe, effective and perfect for use in young children and can be performed in an outpatient unit.

  4. Vulvovaginitis and other common childhood gynaecological conditions.

    PubMed

    Garden, Anne S

    2011-04-01

    Paediatric gynaecological problems, especially those involving the vulvar area, are common in childhood. The conditions frequently seen include recurrent bacterial vulvovaginitis, vulvar irritation, labial adhesions and dermatological conditions. The presentation and management of these conditions will be reviewed.

  5. Preprosthetic minor tooth movement with thermoplastic appliances and interproximal stripping: a clinical report.

    PubMed

    Cho, Seok-Hwan

    2014-11-01

    This clinical report describes preprosthodontic minor tooth movement with serial thermoplastic appliances and interproximal stripping. A patient with rotated and labially tipped anterior teeth sought care with a request for improved appearance. The prosthodontic planning and treatment approach are discussed.

  6. Sonosurgery for atraumatic tooth extraction: a clinical report.

    PubMed

    Papadimitriou, Dimitrios E V; Geminiani, Alessandro; Zahavi, Thomas; Ercoli, Carlo

    2012-12-01

    The preservation of an intact labial plate during tooth extraction is a critical determinant of whether an immediate implant can be placed and is also an important predictor of the esthetic result. The purpose of this clinical report was to present a method for atraumatic tooth extraction by using an air-driven sonic instrument with specially designed inserts. This surgical technique provides the clinician with an efficient method for atraumatic tooth extraction and preservation of an intact labial plate.

  7. Upper-lip laser frenectomy without infiltrated anaesthesia in a paediatric patient: a case report.

    PubMed

    Kafas, Panagiotis; Stavrianos, Christos; Jerjes, Waseem; Upile, Tahwinder; Vourvachis, Michael; Theodoridis, Marios; Stavrianou, Irene

    2009-05-20

    Labial frenectomy is a common surgical procedure in the field of oral surgery. Labial frenectomy is a procedure usually done for orthodontic reasons. The role of laser surgery in the oral cavity is well established. The use of diode laser frenectomy without infiltrated anaesthesia is currently under investigation. Needle-less oral surgery, without infiltrated anaesthesia, is a novel situation in paediatrics with paramount importance.

  8. Language-general biases and language-specific experience contribute to phonological detail in toddlers' word representations.

    PubMed

    Tsuji, Sho; Fikkert, Paula; Yamane, Naoto; Mazuka, Reiko

    2016-03-01

    Although toddlers in their 2nd year of life generally have phonologically detailed representations of words, a consistent lack of sensitivity to certain kinds of phonological changes has been reported. The origin of these insensitivities is poorly understood, and uncovering their cause is crucial for obtaining a complete picture of early phonological development. The present study explored the origins of the insensitivity to the change from coronal to labial consonants. In cross-linguistic research, we assessed to what extent this insensitivity is language-specific (or would show both in learners of Dutch and a very different language like Japanese), and contrast/direction-specific to the coronal-to-labial change (or would also extend to the coronal-to-dorsal change). We measured Dutch and Japanese 18-month-old toddlers' sensitivity to labial and dorsal mispronunciations of newly learned coronal-initial words. Both Dutch and Japanese toddlers showed reduced sensitivity to the coronal-to-labial change, although this effect was more pronounced in Dutch toddlers. The lack of sensitivity was also specific to the coronal-to-labial change because toddlers from both language backgrounds were highly sensitive to dorsal mispronunciations. Combined with results from previous studies, the present outcomes are most consistent with an early, language-general bias specific to the coronal-to-labial change, which is modified by the properties of toddlers' early, language-specific lexicon.

  9. Comparative Study of Fracture Resistance of Porcelain in Metal Ceramic Restorations by Using Different Metal Coping Designs- An In Vitro Study

    PubMed Central

    Motwani, B. K.

    2014-01-01

    Aim: The aim of this study was to compare effect of different metal coping designs on fracture resistance of porcelain in metal ceramic restorations. Materials and Methods: Fracture resistance of porcelain was assessed in porcelain fused to metal crowns with three different coping designs i.e. metal coping extension on labial surface upto gingivoaxial line angle, metal coping extension 1mm short of the gingivoaxial line angle and metal coping with 0.4mm wide labial metal collar. For crowns without labial metal collar margin; shoulder porcelain was used to build the labial cervical margin of the crowns. Results: Results were assessed with statistical analysis using the student unpaired‘t’ test. Visual examination of the fractured specimens of group A, B and C showed remarkably similar failure modes with nearly all specimens failing through a shear fracture of porcelain from load point to facial margin of the crown. Conclusion: Within the scope of this study, it was observed that the mean facture strength of the samples with shoulder porcelain labial margins having metal coping design extending upto gingivoaxial line angle of the finish line was highest as compared to samples with shoulder porcelain labial margins having metal coping design 1mm short of gingivoaxial line angle & samples having porcelain fused to metal coping design with 0.4mm wide metal collar. PMID:25584302

  10. Alveolar bone thickness around maxillary central incisors of different inclination assessed with cone-beam computed tomography.

    PubMed

    Tian, Yu-Lou; Liu, Fang; Sun, Hong-Jing; Lv, Pin; Cao, Yu-Ming; Yu, Mo; Yue, Yang

    2015-09-01

    To assess the labial and lingual alveolar bone thickness in adults with maxillary central incisors of different inclination by cone-beam computed tomography (CBCT). Ninety maxillary central incisors from 45 patients were divided into three groups based on the maxillary central incisors to palatal plane angle; lingual-inclined, normal, and labial-inclined. Reformatted CBCT images were used to measure the labial and lingual alveolar bone thickness (ABT) at intervals corresponding to every 1/10 of the root length. The sum of labial ABT and lingual ABT at the level of the root apex was used to calculate the total ABT (TABT). The number of teeth exhibiting alveolar fenestration and dehiscence in each group was also tallied. One-way analysis of variance and Tukey's honestly significant difference test were applied for statistical analysis. The labial ABT and TABT values at the root apex in the lingual-inclined group were significantly lower than in the other groups (p < 0.05). Lingual and labial ABT values were very low at the cervical level in the lingual-inclined and normal groups. There was a higher prevalence of alveolar fenestration in the lingual-inclined group. Lingual-inclined maxillary central incisors have less bone support at the level of the root apex and a greater frequency of alveolar bone defects than normal maxillary central incisors. The bone plate at the marginal level is also very thin.

  11. A new, mesophotic Coryphopterus goby (Teleostei, Gobiidae) from the southern Caribbean, with comments on relationships and depth distributions within the genus.

    PubMed

    Baldwin, Carole C; Robertson, D Ross

    2015-01-01

    A new species of western Atlantic Coryphopterus is described from mesophotic depths off Curaçao, southern Caribbean. Coryphopteruscurasub sp. n., is similar to Coryphopterusdicrus in, among other features, having two prominent pigment spots of roughly equal intensity on the pectoral-fin base, the pelvic fins fused to form a disk, and no pelvic frenum. The two species can be differentiated by body depth (shallower in Coryphopteruscurasub at origin of dorsal fin and caudal peduncle); differences in the pigmentation on the head, trunk, and basicaudal region; and usually by total number of rays (spinous plus soft) in the second dorsal fin (10-11, usually 11, in Coryphopteruscurasub, 10 in Coryphopterusdicrus). Coryphopteruscurasub differs from other Coryphopterus species that have a prominent pigment spot on the lower portion of the pectoral-fin base (Coryphopteruspunctipectophorus and Coryphopterusvenezuelae) in, among other features, lacking a pelvic frenum. Coryphopteruscurasub was collected between 70 and 80 m, the deepest depth range known for the genus. Collections of Coryphopterusvenezuelae at depths of 65-69 m extend the depth range of that species by approximately 50 m. Mitochondrial cytochrome c oxidase subunit I (COI) data corroborate the recognition of Coryphopteruscurasub as a distinct species but do not rigorously resolve its relationships within the genus. A revised key to the western Atlantic species of Coryphopterus is presented.

  12. A new, mesophotic Coryphopterus goby (Teleostei, Gobiidae) from the southern Caribbean, with comments on relationships and depth distributions within the genus

    PubMed Central

    Baldwin, Carole C.; Robertson, D. Ross

    2015-01-01

    Abstract A new species of western Atlantic Coryphopterus is described from mesophotic depths off Curaçao, southern Caribbean. Coryphopterus curasub sp. n., is similar to Coryphopterus dicrus in, among other features, having two prominent pigment spots of roughly equal intensity on the pectoral-fin base, the pelvic fins fused to form a disk, and no pelvic frenum. The two species can be differentiated by body depth (shallower in Coryphopterus curasub at origin of dorsal fin and caudal peduncle); differences in the pigmentation on the head, trunk, and basicaudal region; and usually by total number of rays (spinous plus soft) in the second dorsal fin (10–11, usually 11, in Coryphopterus curasub, 10 in Coryphopterus dicrus). Coryphopterus curasub differs from other Coryphopterus species that have a prominent pigment spot on the lower portion of the pectoral-fin base (Coryphopterus punctipectophorus and Coryphopterus venezuelae) in, among other features, lacking a pelvic frenum. Coryphopterus curasub was collected between 70 and 80 m, the deepest depth range known for the genus. Collections of Coryphopterus venezuelae at depths of 65–69 m extend the depth range of that species by approximately 50 m. Mitochondrial cytochrome c oxidase subunit I (COI) data corroborate the recognition of Coryphopterus curasub as a distinct species but do not rigorously resolve its relationships within the genus. A revised key to the western Atlantic species of Coryphopterus is presented. PMID:26257572

  13. ANKYLOGLOSSIA AND ITS INFLUENCE ON GROWTH AND DEVELOPMENT OF THE STOMATOGNATHIC SYSTEM.

    PubMed

    Pompéia, Livia Eisler; Ilinsky, Roberta Simoni; Ortolani, Cristina Lúcia Feijó; Faltin, Kurt

    2017-01-01

    To critically examine the existing Brazilian and International scientific literature regarding the influence of short lingual frenulum over growth and development of the stomatognathic system, as well as how it impacts the achievement of the shape-function balance. An electronic literature search was conducted in databases, including MEDLINE/PubMed, Google Scholar, LILACS, SciELO, and ScienceDirect, using the key words "lingual frenum" and "development", as well as their equivalents in Brazilian Portuguese. The literature search yielded 51 papers published between January 1997 and the present date; 14 articles of clinical trials were selected for meeting the inclusion criteria and were read in full. The integrated literature review supported the proposition that some malocclusions are closely related to the presence of ankyloglossia and, although very few clinical trials on this topic have been published so far, there is a consensus among authors concerning the negative effects of functional imbalances over the stomatognathic system's proper growth and development. Half of the studies found state that surgical interventions for releasing the lingual frenum are both safe and effective, concerning improvement in breastfeeding scores. Moreover, 4 out of the 14 studies included in this integrated review, report a negative influence of ankyloglossia over the orofacial muscular system. There is a consensus among the authors concerning the negative effects of lingual frenulum's anatomic and functional alterations over craniofacial growth and development. The opinion about the early surgical intervention, however, is not unanimous.

  14. Presurgical orthodontic decompensation alters alveolar bone condition around mandibular incisors in adults with skeletal Class III malocclusion

    PubMed Central

    Sun, Boyang; Tang, Jun; Xiao, Ping; Ding, Ying

    2015-01-01

    This study is to use cone beam computed tomography (CBCT) to acquire accurate radiographic images for alveolar bone in lower incisors and the change after presurgical orthodontic treatment. Seventeen patients with skeletal Class III malocclusion, ten normal occlusion subjects, and fifteen patients treated with orthodontic treatment and orthognathic surgery were included. CBCT images were obtained. The labial and lingual inclinations of mandibular incisors, the thickness of alveolar bone, the vertical alveolar height and root length were measured. Alveolar bone thickness at the apex in patients with skeletal Class III malocclusion was thinner than normal subjects. The vertical alveolar bone heights at labial and lingual sides in patients with skeletal Class III malocclusion were both reduced compared with normal subjects, especially at the labial side. There were statistically significant correlations between lower incisor inclination and alveolar bone morphology. After orthodontics, the incisors root apex was closer to the lingual side of alveolar bone. The alveolar bone thickness at apex was not statistically changed. The vertical alveolar bone heights at the labial and lingual sides were both significantly reduced especially the lingual side after presurgical orthodontic treatment. The root length was not significantly changed. In conclusion, the alveolar bone thickness at apex is thinner and the vertical alveolar height is reduced at the labial side. Forward movement of lower incisors during presurgical orthodontic treatment can render the lower incisors root apex closer to the lingual side and the vertical alveolar height is reduced. PMID:26550202

  15. Chemical reproductive traits of diploid Bombus terrestris males: Consequences on bumblebee conservation.

    PubMed

    Lecocq, Thomas; Gérard, Maxence; Maebe, Kevin; Brasero, Nicolas; Dehon, Lauren; Smagghe, Guy; Valterová, Irena; De Meulemeester, Thibaut; Rasmont, Pierre; Michez, Denis

    2016-03-07

    The current bumblebee decline leads to inbreeding in populations that fosters a loss of allelic diversity and diploid male production. As diploid males are viable and their offspring are sterile, bumblebee populations can quickly fall in a vortex of extinction. In this paper, we investigate for the first time a potential pre-mating mechanism through a major chemical reproductive trait (male cephalic labial gland secretions) that could prevent monandrous virgin queens from mating with diploid males. We focus our study on the cephalic labial gland secretions of diploid and haploid males of Bombus terrestris (L.). Contrary to initial expectations, our results do not show any significant differentiation of cephalic labial gland secretions between diploid and haploid specimens. Queens seem therefore to be unable to avoid mating with diploid males based on their compositions of cephalic labial gland secretions. This suggests that the vortex of extinction of diploid males could not be stopped through pre-mating avoidance based on the cephalic labial gland secretions but other mechanisms could avoid mating between diploid males and queens. This article is protected by copyright. All rights reserved.

  16. Distribution of the Sex combs reduced Gene Products in Drosophila melanogaster

    PubMed Central

    Mahaffey, James W.; Kaufman, Thomas C.

    1987-01-01

    The spatial and temporal distribution of RNA and protein encoded by the homeotic Sex combs reduced (Scr) gene were examined during Drosophila development. The gene products are present in the epidermis of both the labial and first thoracic segments as would be predicted from prior genetic studies. However, the pattern in the central nervous system (CNS) and mesoderm is further restricted; the major expression located in the labial neuromere of the CNS and the mesoderm of the first thoracic segment. The spatial restriction within the CNS is correlated with and may be due to a differential timing of expression in the labial and first thoracic ectoderm. The labial ectoderm accumulates the Scr RNA prior to segregation of the neuroblasts while expression in the first thoracic ectoderm occurs after neuroblast segregation. The protein is also observed in the subesophageal ganglia of both larvae and adults, as well as in the labial and first thoracic imaginal discs. Surprisingly, the protein is also present to a lesser extent in second and third thoracic leg discs. PMID:3117618

  17. Perception of Place of Articulation for Plosives and Fricatives in Noise.

    PubMed

    Alwan, Abeer; Jiang, Jintao; Chen, Willa

    2011-02-01

    This study aims at uncovering perceptually-relevant acoustic cues for the labial versus alveolar place of articulation distinction in syllable-initial plosives {/b/,/d/,/p/,/t/} and fricatives {/f/,/s/,/v/,/z/} in noise. Speech materials consisted of naturally-spoken consonant-vowel (CV) syllables from four talkers where the vowel was one of {/a/,/i/,/u/}. Acoustic analyses using logistic regression show that formant frequency measurements, relative spectral amplitude measurements, and burst/noise durations are generally reliable cues for labial/alveolar classification. In a subsequent perceptual experiment, each pair of syllables with the labial/alveolar distinction (e.g., /ba,da/) was presented to listeners in various levels of signal-to-noise-ratio (SNR) in a 2-AFC task. A threshold SNR was obtained for each syllable pair using sigmoid fitting of the percent correct scores. Results show that the perception of the labial/alveolar distinction in noise depends on the manner of articulation, the vowel context, and interaction between voicing and manner of articulation. Correlation analyses of the acoustic measurements and threshold SNRs show that formant frequency measurements (such as F1 and F2 onset frequencies and F2 and F3 frequency changes) become increasingly important for the perception of labial/alveolar distinctions as the SNR degrades.

  18. Perception of Place of Articulation for Plosives and Fricatives in Noise✩

    PubMed Central

    Alwan, Abeer; Jiang, Jintao; Chen, Willa

    2010-01-01

    This study aims at uncovering perceptually-relevant acoustic cues for the labial versus alveolar place of articulation distinction in syllable-initial plosives {/b/,/d/,/p/,/t/} and fricatives {/f/,/s/,/v/,/z/} in noise. Speech materials consisted of naturally-spoken consonant-vowel (CV) syllables from four talkers where the vowel was one of {/a/,/i/,/u/}. Acoustic analyses using logistic regression show that formant frequency measurements, relative spectral amplitude measurements, and burst/noise durations are generally reliable cues for labial/alveolar classification. In a subsequent perceptual experiment, each pair of syllables with the labial/alveolar distinction (e.g., /ba,da/) was presented to listeners in various levels of signal-to-noise-ratio (SNR) in a 2-AFC task. A threshold SNR was obtained for each syllable pair using sigmoid fitting of the percent correct scores. Results show that the perception of the labial/alveolar distinction in noise depends on the manner of articulation, the vowel context, and interaction between voicing and manner of articulation. Correlation analyses of the acoustic measurements and threshold SNRs show that formant frequency measurements (such as F1 and F2 onset frequencies and F2 and F3 frequency changes) become increasingly important for the perception of labial/alveolar distinctions as the SNR degrades. PMID:21499546

  19. The impact of frenulum height on strains in maxillary denture bases

    PubMed Central

    Bilhan, Hakan; Baysal, Gokhan; Sunbuloglu, Emin; Bozdag, Ergun

    2013-01-01

    PURPOSE The midline fracture of maxillary complete dentures is a frequently encountered complication. The purpose of this study was to assess the effect of frenulum height on midline strains of maxillary complete dentures. MATERIALS AND METHODS A removable maxillary complete denture was fabricated and duplicated seven times. Four different labial frenulum heights were tested for stresses occurring on the palatal cameo surface. The strains were measured with strain gauges placed on 5 different locations and the stresses were calculated. To mimic occlusal forces bilaterally 100 N of load was applied from the premolar and molar region. RESULTS A statistically significant association between the height of the labial frenulum and the calculated stresses and strains was shown (P<.05) predominantly on the midline and especially on the incisive papilla. The results showed that stress on the anterior midline of the maxillary complete denture increases with a higher labial frenulum. CONCLUSION Within the limitations of this in vitro study, it can be concluded that the stress on the anterior midline of the maxillary complete denture increases with a higher labial frenulum. Surgical or mechanical precautions should be taken to prevent short-term failure of maxillary complete dentures due to stress concentration and low cycle fatigue tendency at the labial frenulum region. PMID:24353878

  20. Phenotypic flexibility of gape anatomy fine-tunes the aquatic prey-capture system of newts.

    PubMed

    Van Wassenbergh, Sam; Heiss, Egon

    2016-07-07

    A unique example of phenotypic flexibility of the oral apparatus is present in newts (Salamandridae) that seasonally change between an aquatic and a terrestrial habitat. Newts grow flaps of skin between their upper and lower jaws, the labial lobes, to partly close the corners of the mouth when they adopt an aquatic lifestyle during their breeding season. Using hydrodynamic simulations based on μCT-scans and cranial kinematics during prey-capture in the smooth newt (Lissotriton vulgaris), we showed that this phenotypic flexibility is an adaptive solution to improve aquatic feeding performance: both suction distance and suction force increase by approximately 15% due to the labial lobes. As the subsequent freeing of the corners of the mouth by resorption of the labial lobes is assumed beneficial for the terrestrial capture of prey by the tongue, this flexibility of the mouth fine-tunes the process of capturing prey throughout the seasonal switching between water and land.

  1. Phenotypic flexibility of gape anatomy fine-tunes the aquatic prey-capture system of newts

    PubMed Central

    Van Wassenbergh, Sam; Heiss, Egon

    2016-01-01

    A unique example of phenotypic flexibility of the oral apparatus is present in newts (Salamandridae) that seasonally change between an aquatic and a terrestrial habitat. Newts grow flaps of skin between their upper and lower jaws, the labial lobes, to partly close the corners of the mouth when they adopt an aquatic lifestyle during their breeding season. Using hydrodynamic simulations based on μCT-scans and cranial kinematics during prey-capture in the smooth newt (Lissotriton vulgaris), we showed that this phenotypic flexibility is an adaptive solution to improve aquatic feeding performance: both suction distance and suction force increase by approximately 15% due to the labial lobes. As the subsequent freeing of the corners of the mouth by resorption of the labial lobes is assumed beneficial for the terrestrial capture of prey by the tongue, this flexibility of the mouth fine-tunes the process of capturing prey throughout the seasonal switching between water and land. PMID:27383663

  2. Phenotypic flexibility of gape anatomy fine-tunes the aquatic prey-capture system of newts

    NASA Astrophysics Data System (ADS)

    van Wassenbergh, Sam; Heiss, Egon

    2016-07-01

    A unique example of phenotypic flexibility of the oral apparatus is present in newts (Salamandridae) that seasonally change between an aquatic and a terrestrial habitat. Newts grow flaps of skin between their upper and lower jaws, the labial lobes, to partly close the corners of the mouth when they adopt an aquatic lifestyle during their breeding season. Using hydrodynamic simulations based on μCT-scans and cranial kinematics during prey-capture in the smooth newt (Lissotriton vulgaris), we showed that this phenotypic flexibility is an adaptive solution to improve aquatic feeding performance: both suction distance and suction force increase by approximately 15% due to the labial lobes. As the subsequent freeing of the corners of the mouth by resorption of the labial lobes is assumed beneficial for the terrestrial capture of prey by the tongue, this flexibility of the mouth fine-tunes the process of capturing prey throughout the seasonal switching between water and land.

  3. Pragmatic and Profound Benefits of Acyclovir Buccal Adhesive Tablets.

    PubMed

    Rosen, Ted

    2016-06-01

    The clinician has many options, both systemic and topical, for the management of oro-labial herpes simplex infections due to HSV-1. A recent addition to this armamentarium is Acyclovir 50 mg Buccal Adhesive Tablets (ABT 50mg). While this agent demonstrates the typical modest reduction in time to healing of any given episode of recurrent oro-labial HSV 1, it also was found in pivotal studies to alter the course of this troublesome viral disease. Several case reports are presented which dramatically illustrate that ABT 50mg can reduce the overall number of overt outbreaks and increase the time interval between outbreaks in patients with historical evidence of frequent episodes. This therapeutic intervention is thus: simple, safe, efficacious and cost-effective, even in patients who experience numerous (and therefore disconcerting) oro-labial outbreaks.

    J Drugs Dermatol. 2016;15(6):775-777.

  4. Dentoalveolar trauma in a patient with chronic idiopathic thrombocytopenic purpura: a case report.

    PubMed

    Finucane, David; Fleming, Padraig; Smith, Owen

    2004-01-01

    A case is presented of a 13-year-old boy with chronic idiopathic thrombocytopenic purpura (ITP) who sustained traumatic labial luxation of both lower central incisors, with partial alveolar fracture resulting in displacement of the labial alveolar plate. Intravenous immunoglobulin (Fleibogamma, 1 g/kg body weight x 2 days) was administered, resulting in the patient's platelet count rising from 15,000/mm3 to 70,000/mm3. Under general anesthesia, the displaced lower labial alveolus and luxated teeth were repositioned and splinted 2 days following trauma. Healing was uneventful. Subsequently, both lower central incisors became nonvital and were endodontically treated. The dental treatment of this patient with ITP is discussed in terms of emergency management, and subsequent care.

  5. Congenital defect of maxillary primary central incisor associated with exposed pulp and gingival [fibrosis]: case report.

    PubMed

    Sano, Tomiko; Tomizawa, Mieko; Ida-Yonemochi, Hiroko; Tanabe, Yoshihiro; Noda, Tadashi

    2003-01-01

    This report describes a rare case of hypoplastic primary incisor in which the pulp was exposed at the crown portion and covered by the gingiva in a 1-year-11-month-old boy. The patient was referred to us due to swelling of his labial cervical gingiva of the maxillary right primary central incisor, and on examination, extended to the hypoplastic labial surface. Radiographically, there was a round radiolucent area on the crown including the edge. Surgical removal of the swollen gingiva revealed a large defect of the labial aspect of the incisor, showing pulpal tissue inside. The tooth was treated by vital pulpotomy. Histopathologically, the removed gingival tissue contained many pieces of dysplastic tooth elements in the lamina propria portion which should have been connected to the exposed pulp. The findings suggested that pulp exposure resulted from focal dental hypoplasia not from resorption of the tooth.

  6. Lexical and phonotactic effects on the perception of rate induced resyllabification

    NASA Astrophysics Data System (ADS)

    de Jong, Kenneth; Nagao, Kyoko; Lim, Byung-Jin; Okamura, Kyoko

    2002-05-01

    Stetson (1951) noted that, when repeated, singleton coda consonants (VC) appear to modulate into onset consonants (CV) as the rate of repetition increases. de Jong et al. (2001) found that naEe listeners robustly perceive such resyllabifications with labial consonants, and in a later study, that such perceptions broadly corresponded to changes in glottal timing. In the current study, stimuli included labial, coronal, and velar stops, creating mixtures of real words (such as ``eat''), and nonwords (such as ``ead''). A comparison of the perception of real and nonreal words reveals no robust effect of lexical status. In addition, vowels in the corpus were either tense or lax, so that the CV combination is phonotactically illegal in half of the corpus. The perception of resyllabification also does occur with these lax vowels, though only for voiced coronal and labial stops. Other stops did not exhibit resyllabification. Analyses of glottal and acoustic recordings are currently underway. [Work supported by NIDCD and NSF.

  7. Anterior tooth morphology and its effect on torque.

    PubMed

    van Loenen, M; Degrieck, J; De Pauw, G; Dermaut, L

    2005-06-01

    This study was undertaken to determine the variation in crown-root angle (CRA) of the upper incisors and canines as well as the variation in their labial contour. In addition, the influence of the variability of the labial contour and of different bracket heights on torque was evaluated. Proximal radiographs were taken of 160 extracted maxillary teeth (81 incisors and 79 canines). They were digitized and analysed with Jasc Paint Shop Pro 7TM and Mathcad 2001 Professional. The incisal edge, the centre of the cemento-enamel junction (CEJ), and the root apex were digitized to define the crown and root long axis. For all teeth the CRA was measured. At several heights of the labial surface a tangent was determined, enabling measurement of the inclination of the labial surface. The CRA had great variability, ranging from 167 to 195 degrees for the canines (mean value 183 degrees) and from 171 to 195 degrees for the incisors (average 184 degrees). The mean inclinations of the labial surfaces for the incisors varied greatly. Between 4 and 4.5 mm from the incisal edge the standard deviations (SD) were the smallest and between 2 and 4.5 mm from the incisal edge the labial surface angle differed by approximately 10 degrees. For the canines the mean inclinations of the buccal surface also varied. This angle differed by around 10 degrees between 2 and 4.5 mm from the incisal edge, but the SD were much larger than for the incisors. It can be concluded that placement of a bracket on a tooth at varying heights, still within a clinically acceptable range, results in important differences in the amount of root torque.

  8. A clinical study of periodontal disease in sheep.

    PubMed

    Morris, P L; Whitley, B D; Orr, M B; Laws, A J

    1985-06-01

    Detailed examinations were made of the central permanent incisors and periodontia of 30 or 40 ewes on each of one control farm and three periodontal disease (P.D.) farms. The study confirmed that incisor crown lengthening, protrusion and loosening were significant features of P.D. Periodontitis (assessed by increased sulcus depth and bleeding after probing) about the lingual sulcus was a significant feature of P.D. Labial gingivitis and labial periodontitis were not significant features. A relatively long lower jaw did not appear to be a feature of P.D. 87.

  9. [Fusion of the labia minora as a cause of urinary incontinence in a postmenopausal woman. A case report and literature review].

    PubMed

    Nevarez Bernal, Roberto Armando; Meraz Avila, Diego

    2009-06-01

    Labial fusion is rarely presented in the postmenopausal age group, its predisposing factors are hipoestrogenism and a inflamation/repair process in the vaginal epithelium. Our case report involves a 73 years old woman that presents with urinary incontinence. On physical exploration, complete labial fusion was noted, a surgical approach was undertaken with liberation of the labia and fixation, postoperatory local estrogen ointment was indicated with complete recovery. The literature review confirmed that this was the ideal treatment and also confirms the role of local estrogen ointment as profilactic and therapeutic.

  10. [Anatomic bone and dento-alveolar changes in patients with lip incompetence].

    PubMed

    Pantoja, R; Cortes, J; Argandoña, J; Encina, S

    1995-01-01

    Twenty young patients with clinical labial incompetence have been studied cefalometrically using Delaire's Analysis, in order to determine anatomical alterations who explains this condition. In all of them we have found some anatomical alteration in sagital or vertical plane or both, in maxillary or mandibular squeletal bases or their dento-alveolar squeletic unit. Knowledge of anatomical factors contributing or determining labial incompetence is the key of the planification and execution of an etiologic approach, what is the best way to obtain physiological rapport and consequently good aesthetic results.

  11. Description of the final instar larva of Pseudagrion pruinosum (Burmeister, 1839) (Odonata: Coenagrionidae) from Thailand.

    PubMed

    Saetung, Tosaphol; Boonsoong, Boonsatien

    2016-10-14

    Herein the final instar larva of Pseudagrion pruinosum (Burmeister, 1839) is described and illustrated for the first time, based on reared specimens from Thailand. When compared with the other known Pseudagrion larvae, P. pruinosum is distinguished by three setae on the labial palp, five teeth on the truncate, denticulate lobe on the distal marginal end of the labial palp, one premental seta and a row of three minute setae on each side of the midline, as well as shape and tracheation of caudal gills.

  12. [The diagnostic value of anti-SSA antibody in primary Sjögren's syndrome].

    PubMed

    Li, Meng-tao; Zhao, Yan; Zheng, Wen-jie; Su, Jin-mei; Wu, Qing-jun; Jiang, Ying; Xu, Dong; Zhang, Wen; Zhang, Feng-chun; Dong, Yi

    2010-05-01

    According to international classification criteria (2002) on Sjögren's syndrome, labial pathology was still considered as a major criterion for diagnosis. Standard labial biopsy was hard to be carried out in China. This study is to evaluate whether the invasive labial biopsy could be replaced by noninvasive detection of serum anti-SSA antibody. 181 Chinese patients with the initial diagnosis of primary Sjögren's syndrome in Peking Union Medical College Hospital (PUMCH) were enrolled in Sjögren's International Collaborative Clinical Alliance (SICCA). All patients received standard labial biopsies (area of salivary gland tissue ≥ 4 mm²) and focal score (FS) of focal lymphatic sialadenitis were confirmed by pathologists from school of stomatology, University California of San Francisco (UCSF). Anti-SSA antibodies in sera of all patients were detected by double immunodiffusion (DID), Western blot in PUMCH and by enzyme-linked immunosorbent assay (ELISA) in central laboratory of SICCA. The correlation between labial pathological findings and serum anti-SSA antibody was studied by chi² test and the concordance was calculated by unweighted Kappa. (1) Bivariate analysis revealed strong associations of FS > 1 with the presence of anti-SSA antibody by DID (83.9% vs 42.0%, P < 0.0001). The accordance between FS and antibody detection by DID was fine with a kappa value of 0.432. However, there were 16.1% false-positive antibody reports and 42.0% false-negative antibody reports. (2) FS > 1 was strongly associated with the presence of anti-SSA antibody by Western blot (83.0% vs 51.7%, P < 0.0001). But the accordance between FS and antibody detection by Western blot was only fair with a kappa value of 0.316. There were 17.0% false-positive antibody reports and 51.7% false-negative antibody reports. (3) FS > 1 was strongly associated with the presence of anti-SSA antibody by ELISA (81.5% vs 38.6%, P < 0.0001). The accordance between FS and antibody detection by ELISA was

  13. Surface strains induced by measured loads on teeth in vivo: a methodological study.

    PubMed

    Nohl, F S; Setchell, D J

    2000-03-01

    Visual feedback enabled three subjects to apply predetermined near-axial loads to the incisal edge of an intact maxillary central incisor. In two subjects, principal strains and orientations developed on the labial surface of the intact incisor were resolved from strains recorded with a multiple element strain gauge. Load application was accurate and precise enough to allow resolution of strains induced by target loads of 10 to 50 N. Axially orientated compressive labial surface strains were induced by measured loads. The method could be used to validate bench-top stress analyses and investigate the effects of restoration on the structural integrity of teeth.

  14. Comparative evaluation of two different vestibuloplasty surgical procedures in cleft patients: a pilot study.

    PubMed

    de Almeida, Ana Lúcia Pompéia Fraga; Pedro, Patrícia Franco; Kogawa, Evelyn Mikaela; Pereira, Tatiana; de Barros Carrilho, Guilherme Paes; Aiello, Carlos Alberto; Freitas, Patrícia Zambonato

    2005-07-01

    Patients with a cleft lip or palate often present alterations in the labial aspect of the ridge, resulting in a shallow vestibule. This study compares the results of two different surgical procedures on deepening of the labial sulcus. Ten patients with a cleft lip and palate were separated into two groups and underwent different vestibuloplasty procedures. An experimental group used a removable retention splint. Preoperative and 4-month postoperative sulcus heights were measured and analyzed statistically. No statistically significant differences could be detected between groups. The results indicated that to reach consistent results, a larger number of patients must be submitted to this evaluation.

  15. Is use of laser really essential for release of tongue-tie?

    PubMed

    Sane, Vikrant Dilip; Pawar, Sudhir; Modi, Sachin; Saddiwal, Rashmi; Khade, Mayur; Tendulkar, Hrishikesh

    2014-05-01

    Ankyloglossia, or tongue-tie, is a congenital condition characterized by a short, thickened, or abnormally tight lingual frenulum. This anomaly can cause a varying degree of reduced tongue mobility and has been associated with functional limitations including breastfeeding difficulties, atypical swallowing habits, speech articulation problems, mechanical problems such as inability to clean the oral cavity, and psychosocial stress. In this article, we report a 50-year-old female patient with tongue-tie having difficulty in speech and maintenance of oral hygiene due to high attachment of lingual frenum. The patient was managed by frenectomy by conventional method (scalpel and blade) under local anesthesia as an outpatient procedure without any complications. She later required speech therapy lessons for improvement of speech.

  16. Acellular dermal allograft for vestibuloplasty--an alternative to autogenous soft tissue grafts in preprosthetic surgical procedures: a clinical report.

    PubMed

    Bhola, Monish; Newell, Donald H; Hancock, Everett B

    2003-06-01

    Various vestibular extension procedures have been described in the literature over the past 6 decades, including the use of free gingival grafts. An acellular dermal allograft has been used as a substitute for autogenous soft tissue grafts in root coverage procedures. This clinical report describes the use of such an allograft as a substitute for palatal donor tissue in the vestibular extension of an edentulous maxillary arch with multiple frenum attachments before fabrication of a complete denture. In this patient, healing was uneventful, and 6-month clinical observations demonstrated an apical positioning of the mucogingival junction with an increase in vestibular depth, and the absence of multiple frenae. The acellular dermal allograft appears to be a useful substitute for autogenous palatal grafts in preprosthetic surgery. This approach has many advantages over the free gingival graft, including no donor site morbidity, unlimited availability, and better color match.

  17. Frenectomy with semilunar coronally repositioned flap: A single stage approach - simple solution for complex problem.

    PubMed

    Deshmukh, Jeevanand; Khatri, Richa; Fernandes, Bennete; Kulkarni, Vinaya Kumar; Singh, Shubhra

    2015-01-01

    Gingival recession is defined as the displacement of gingival margin apical to cementoenamel junction. Aberrant frenum attachment can contribute to the progression of recession by generating tension on the marginal tissues. Treating such defects is a two stage procedure-frenectomy and recession coverage procedure. New techniques are developed to increase the predictability, reduce patient discomfort and number of surgical sites. Also, these techniques try to satisfy patients esthetic demands, which include the final colour and tissue blend of the covered area. In this case report, we present a method for coronally repositioning gingiva for root coverage over the maxillary central incisors while simultaneously performing a frenectomy, thus being clinically advantageous compared to two-stage technique.

  18. A Novel Surgical Pre-suturing Technique for the Management of Ankyloglossia.

    PubMed

    Khairnar, Mayur; Pawar, Babita; Khairnar, Darshana

    2014-01-01

    Ankyloglossia or "tongue-tie" is a congenital anomaly caused by tight lingual frenulum that abnormally connects the tongue base to the floor of the mouth. Ankyloglossia can results in difficulty during speech and deglutition. This case series presents a novel surgical technique in the management of ankyloglossia in using presuturing technique in which different sets of sutures are given on lingual frenum before severing it. This results in reduced opening of the wound, minimal bleeding, pain and discomfort. Two male patients with severe ankyloglossia had been managed with this technique and after 2 years of follow-up of these cases showed satisfactory protrusive and lateral movement of the tongue with minimal scarring and discomfort.

  19. Frenectomy with semilunar coronally repositioned flap: A single stage approach - simple solution for complex problem

    PubMed Central

    Deshmukh, Jeevanand; Khatri, Richa; Fernandes, Bennete; Kulkarni, Vinaya Kumar; Singh, Shubhra

    2015-01-01

    Gingival recession is defined as the displacement of gingival margin apical to cementoenamel junction. Aberrant frenum attachment can contribute to the progression of recession by generating tension on the marginal tissues. Treating such defects is a two stage procedure-frenectomy and recession coverage procedure. New techniques are developed to increase the predictability, reduce patient discomfort and number of surgical sites. Also, these techniques try to satisfy patients esthetic demands, which include the final colour and tissue blend of the covered area. In this case report, we present a method for coronally repositioning gingiva for root coverage over the maxillary central incisors while simultaneously performing a frenectomy, thus being clinically advantageous compared to two-stage technique. PMID:26392698

  20. A Novel Surgical Pre-suturing Technique for the Management of Ankyloglossia

    PubMed Central

    Khairnar, Mayur; Pawar, Babita; Khairnar, Darshana

    2014-01-01

    Ankyloglossia or “tongue-tie” is a congenital anomaly caused by tight lingual frenulum that abnormally connects the tongue base to the floor of the mouth. Ankyloglossia can results in difficulty during speech and deglutition. This case series presents a novel surgical technique in the management of ankyloglossia in using presuturing technique in which different sets of sutures are given on lingual frenum before severing it. This results in reduced opening of the wound, minimal bleeding, pain and discomfort. Two male patients with severe ankyloglossia had been managed with this technique and after 2 years of follow-up of these cases showed satisfactory protrusive and lateral movement of the tongue with minimal scarring and discomfort. PMID:25598942

  1. Buccinator muscle repositioning

    PubMed Central

    Baghele, Om N.

    2012-01-01

    Anatomical aberrations and abnormalities are frequently associated with functional, psychosocial, and emotional problems. One such aberration is crestal attachment of frenum or muscle on the alveolar processes of the jaws. Crestal attachment of buccinator muscle is a rare phenomenon, which may pose various problems in routine oral exercises/functions or restoring the edentulous area. A case of abnormal buccinator muscle attachment is presented here, which was relocated apically by surgical means using an acrylic stent. The healing was uneventful and significant apical repositioning was observed. A fixed bridge was fabricated and the long-term results of the restorative therapy were assured because the patient could maintain the oral hygiene well after the muscle repositioning operation. PMID:23162347

  2. Two new species of Coryogalops (Perciformes: Gobiidae) from the Red Sea .

    PubMed

    Kovačić, Marcelo; Bogorodsky, Sergey V; Mal, Ahmad O

    2014-11-10

    Two new species of the gobiid genus Coryogalops, C. guttatus sp. nov. and C. pseudomonospilus sp. nov., are described from the Red Sea. Coryogalops guttatus sp. nov. is distinguished from its congeners by having dorsal-fin rays VI + I,12; anal-fin rays I,10-11; pectoral-fin rays 17, three upper rays with free tips; pelvic fins I,5, joined to form a disc, weakly emarginate, with pelvic frenum reduced; longitudinal scale series 33-35; transverse scale rows 9-10; circumpeduncular scales 10-11; seven transverse suborbital rows of sensory papillae on cheek; no tentacle above upper eye margin; anterior nostril tubular, with triangular lappet extending from posterior rim, posterior nostril slightly raised; dark orange spots on many of the scales below body midline form a longitudinal pattern, each spot covering one scale; two distinct dark spots behind edge of preopercle, and similar pair of spots at pectoral-fin base. Coryogalops pseudomonospilus sp. nov. is distinguished from congeners by having dorsal-fin rays VI + I,11; anal-fin rays I,10; pectoral-fin rays 16-17, two upper rays with free tips; pelvic fins I,5, joined to form a disc, moderately emarginate, with pelvic frenum well-developed; longitudinal scale series 33-35; transverse scales rows 9; circumpeduncular scales 12; seven transverse suborbital rows of sensory papillae on cheek; no tentacle above upper eye margin; anterior nostril tubular, without lappet from posterior rim, posterior nostril slightly raised; and irregular dark maroon mark covering lower part of the first three membranes between spines of first dorsal fin. The distribution of species restricted to the western Indian Ocean is discussed, and a key to the species of the genus is provided.

  3. Retracted stylets in nymphs of the Asian citrus psyllid are held externally against the clypeus by a special paired organ not found in the adults

    USDA-ARS?s Scientific Manuscript database

    Differences in ultrastructure of the mouthparts in nymphs and adults of the Asian citrus psyllid Diaphorina citri (Hemiptera, Psyllidae), vector of the bacterium associated with citrus huanglongbing disease, were studied using scanning electron microscopy. The number of sensilla on the labial tip in...

  4. A bimaxillary sports mouthguard: a modified technique.

    PubMed

    Milward, P J; Jagger, R G

    1997-12-01

    The bimaxillary mouthguard provides enhanced protection for a participant in contact sports. This article describes the fabrication of a polyvinylacetate-polyethylene (PVAc-PE) bimaxillary mouthguard in which the connection of the maxillary and mandibular components is reinforced by pressure thermoforming a 2-mm PVAc-PE sheet over the labial and buccal portions of the mouthguard.

  5. External morphology of stable fly (Diptera: Muscidae) larvae

    USDA-ARS?s Scientific Manuscript database

    Scanning electron microscopy was used to examine the external morphology of first-, second-, and third-instar stable flies (Stomoxys calcitrans (L.)). In the cephalic region, the antennae, labial lobe, and maxillary palpi are morphologically similar among instars. Antennae comprise a prominent ante...

  6. Biomechanically Preferred Consonant-Vowel Combinations Fail to Appear in Adult Spoken Corpora

    ERIC Educational Resources Information Center

    Whalen, D. H.; Giulivi, Sara; Nam, Hosung; Levitt, Andrea G.; Halle, Pierre; Goldstein, Louis M.

    2012-01-01

    Certain consonant/vowel (CV) combinations are more frequent than would be expected from the individual C and V frequencies alone, both in babbling and, to a lesser extent, in adult language, based on dictionary counts: Labial consonants co-occur with central vowels more often than chance would dictate; coronals co-occur with front vowels, and…

  7. Development and Psychometric Evaluation of the Treatment-Emergent Activation and Suicidality Assessment Profile

    ERIC Educational Resources Information Center

    Reid, Jeannette M.; Storch, Eric A.; Murphy, Tanya K.; Bodzin, Danielle; Mutch, P. Jane; Lehmkuhl, Heather; Aman, Michael; Goodman, Wayne K.

    2010-01-01

    Although effective in treating a range of childhood psychiatric conditions, selective serotonin reuptake inhibitors (SSRI) have been implicated in the induction of an "activation syndrome" (characterized by symptoms of irritability, restlessness, emotional labiality, etc.) that may represent an intermediary state change that fosters…

  8. Face-Referenced Measurement of Perioral Stiffness and Speech Kinematics in Parkinson's Disease

    ERIC Educational Resources Information Center

    Chu, Shin Ying; Barlow, Steven M.; Lee, Jaehoon

    2015-01-01

    Purpose: Perioral biomechanics, labial kinematics, and associated electromyographic signals were sampled and characterized in individuals with Parkinson's disease (PD) as a function of medication state. Method: Passive perioral stiffness was sampled using the OroSTIFF system in 10 individuals with PD in a medication ON and a medication OFF state…

  9. Phonological and Phonetic Asymmetries of Cw Combinations

    ERIC Educational Resources Information Center

    Suh, Yunju

    2009-01-01

    This thesis investigates the relationship between the phonological distribution of Cw combinations, and the acoustic/perceptual distinctiveness between syllables with plain C onsets and with Cw combination onsets. Distributional asymmetries of Cw combinations discussed in this thesis include the avoidance of Cw combinations in the labial consonant…

  10. Ordered Rules and the Morphophonemics of the N-Class in Swahili. York Papers in Linguistics, No. 2.

    ERIC Educational Resources Information Center

    Goyvaerts, D.L.

    This article argues for a set of ordered rules for morphophonemic alternations in the N-class in Swahili, positing /n/ as the class prefix and an abstract segment as stem initial in certain words. The rules are: (1) liquids and the labial glide become corresponding voiced stops; (2) the nasal prefix assimilates in coronality and backness, and…

  11. Underlying Phoneme Velar Nasal with Lip Rounding in Hueyapan Nahuatl

    ERIC Educational Resources Information Center

    Campbell, R. Joe

    1976-01-01

    Reasons are given for the idea that Hueyapan (Morelos) Nahuatl has an underlying velar nasal with lip rounding phoneme which never has the surface reflex of a rounded velar nasal allophone, but occurs phonetically as a velar nasal allophone or a labial dental voiced allophone or disappears. (SCC)

  12. Oral Verrucous Carcinoma Mimicking a Chronic Candidiasis: A Case Report

    PubMed Central

    Garcia, Natália Galvão; Oliveira, Denise Tostes; Hanemann, João Adolfo Costa; Pereira, Alessandro Antônio Costa

    2012-01-01

    Verrucous carcinoma has a special propensity to mimic benign lesions of the oral cavity. A case of the oral verrucous carcinoma in maxillary alveolar ridge, extending to buccal vestibule, cheek, and labial mucosa, which was diagnosed and initially treated as chronic candidiasis, is presented. Clinical, histopathological, and therapeutic considerations related to diagnosis of the verrucous carcinoma in the oral cavity are discussed. PMID:22720181

  13. Development and Psychometric Evaluation of the Treatment-Emergent Activation and Suicidality Assessment Profile

    ERIC Educational Resources Information Center

    Reid, Jeannette M.; Storch, Eric A.; Murphy, Tanya K.; Bodzin, Danielle; Mutch, P. Jane; Lehmkuhl, Heather; Aman, Michael; Goodman, Wayne K.

    2010-01-01

    Although effective in treating a range of childhood psychiatric conditions, selective serotonin reuptake inhibitors (SSRI) have been implicated in the induction of an "activation syndrome" (characterized by symptoms of irritability, restlessness, emotional labiality, etc.) that may represent an intermediary state change that fosters…

  14. Segmental Properties of Input to Infants: A Study of Korean

    ERIC Educational Resources Information Center

    Lee, Soyoung; Davis, Barbara L.; MacNeilage, Peter F.

    2008-01-01

    Segmental distributions of Korean infant-directed speech (IDS) and adult-directed speech (ADS) were compared. Significant differences were found in both consonant and vowel patterns. Korean-speaking mothers using IDS displayed more frequent labial consonantal place and less frequent coronal and glottal place and fricative manner. They showed more…

  15. Paralinguistic Qualifiers: Our Many Voices.

    ERIC Educational Resources Information Center

    Poyatos, Fernando

    1991-01-01

    A case is made for the increased study of paralinguistic voice qualifiers, which include variations in breathing, laryngeal, esophageal, pharyngeal, velopharyngeal, lingual, labial, mandibular, articulatory, articulatory tension, and objectual control. It is proposed that attention to these voice qualities has a variety of practical, literary,…

  16. Sjögren's syndrome: a stepwise approach to the use of diagnostic tests.

    PubMed Central

    Coll, J; Porta, M; Rubiés-Prat, J; Gutiérrez-Cebollada, J; Tomás, S

    1992-01-01

    One hundred and forty two patients (62 with definite Sjögren's syndrome, 24 with probable Sjögren's syndrome, and 56 in whom Sjögren's syndrome was finally ruled out) were studied. Schirmer's test and rose bengal staining for the diagnosis of keratoconjunctivitis sicca and salivary scintigraphy and a labial biopsy sample for the diagnosis of xerostomaia were studied in all patients. Rose bengal staining showed high specificity (98%) but low sensitivity (55%). All patients with positive rose bengal staining results had associated xerostomia. In the rose bengal staining positive patients, scintigraphy had 100% specificity. A labial biopsy sample showed high sensitivity in the rose bengal staining, salivary scintigraphy positive group, and high specificity in the rose bengal staining positive, salivary scintigraphy negative group. In patients with negative rose bengal staining, salivary scintigraphy showed 96% specificity and 36% sensitivity. A labial biopsy sample had a sensitivity and specificity greater than 90% in rose bengal staining negative patients. Only 29 biopsy samples were needed to achieve a diagnosis of Sjögren's syndrome in 142 patients (20%). Hence the suggested approach may make it unnecessary to take biopsy samples in approximately 80% of patients with suspected Sjögren's syndrome. Using the stepwise approach of first rose bengal staining, then salivary scintigraphy, and eventually a labial biopsy sample in patients with suspected Sjögren's syndrome, the diagnosis is relatively simple. PMID:1616324

  17. Mouthpart structure and elemental composition of the mandibles in the coffee berry borer, Hypothenemus hampei (Coleoptera: Curculionidae: Scolytinae)

    USDA-ARS?s Scientific Manuscript database

    The various parts of the mouth in the coffee berry have been identified using scanning electron microscopy. The labial and maxillary palpi are three jointed and connected by a membrane that allows for telescoping. The maxillary palpi contain two types of sensilla (basiconic and campaniform) within a...

  18. Biomechanically Preferred Consonant-Vowel Combinations Fail to Appear in Adult Spoken Corpora

    ERIC Educational Resources Information Center

    Whalen, D. H.; Giulivi, Sara; Nam, Hosung; Levitt, Andrea G.; Halle, Pierre; Goldstein, Louis M.

    2012-01-01

    Certain consonant/vowel (CV) combinations are more frequent than would be expected from the individual C and V frequencies alone, both in babbling and, to a lesser extent, in adult language, based on dictionary counts: Labial consonants co-occur with central vowels more often than chance would dictate; coronals co-occur with front vowels, and…

  19. Towards a Phonetic Explanation for Universal Preferences in Implosives and Ejections.

    ERIC Educational Resources Information Center

    Javkin, Hector

    Two possible explanations based on elementary facts of physics are suggested for the universal preference for place of articulation of implosives and ejectives. Languages show a preference for ejectives in the order: velar, alveolar, and labial while implosives occur most often in the opposite order. A language will only have velar implosives if…

  20. Abfraction lesion formation in maxillary incisors, canines and premolars: a finite element study.

    PubMed

    Rees, J S; Hammadeh, M; Jagger, D C

    2003-04-01

    Abfraction lesions are angular, wedge-shaped defects found at the cervical region of teeth and are caused by mechanical overloading initiated by cuspal flexure. Clinically, these lesions are more prevalent on the labial aspect of maxillary incisors. The aim of this study was to provide a biomechanical explanation for this clinical variation. Two-dimensional plane strain finite element models of an maxillary incisor, canine and first premolar were developed and the cervical stress profiles were examined along a horizontal plane 1.1 mm above the amelo-cemental junction. The local X (horizontal) stress on the labial/buccal side was 176.4 MPa for the incisor, 57.8 MPa for the premolar, and 3.4 MPa for the canine. Similarly, the maximum labial/buccal principal stress was 181.4 MPa for the incisor, 25.2 MPa for the premolar, and 66.8 MPa for the canine. The labial/buccal stress profile in the cervical region of an maxillary incisor was always greater than that found in an maxillary canine or premolar tooth. These findings provide a biomechanical explanation for the clinical variation seen in the prevalence of cervical abfraction lesions.

  1. Grandfather Effects: A Longitudinal Case Study of the Phonological Acquisition of Intervocalic Consonants in English

    ERIC Educational Resources Information Center

    Barlow, Jessica A.

    2007-01-01

    In this article, I present a longitudinal study of a child's (male, aged 3;0-3;4) acquisition of intervocalic consonants characterized within the framework of Optimality Theory (OT). At Stage I, the child presents with unusual error patterns, weakening and labial substitution, and shows evidence of phonologically opaque surface forms. These…

  2. Smile analysis in rhinoplasty: a randomized study for comparing resection and transposition of the depressor septi nasi muscle.

    PubMed

    Kalantar-Hormozi, Abdoljalil; Beiraghi-Toosi, Arash

    2014-02-01

    The depressor septi nasi muscle is responsible for smiling deformity. Its manipulation is beneficial in patients with muscle hypertrophy. In addition, it enhances the smile and tip-lip relationship. In this study, depressor septi nasi muscle excision through a transfixion incision is compared with its transposition through an upper labial sulcus incision. Two techniques of depressor septi nasi muscle treatment were performed randomly for rhinoplasty cases. Smile analysis in rhinoplasty, consisting of measurements of nasal length, nasal diagonal, tip projection, and upper lip height, and noting transverse upper labial crease in repose and full smile, was performed on preoperative and postoperative photographs. One hundred patients were studied in two equal groups. Preoperatively, tip projection and upper lip height were decreased significantly with smiling. Generally, the effect of smiling on all five parameters was decreased significantly following rhinoplasty. The two different techniques were not significantly different in decreasing the effects of smiling on nasal length, nasal diagonal, tip projection, upper lip height, or transverse crease. The two different techniques were the same in decreasing the effects of smiling. The authors recommend smile analysis in rhinoplasty, consisting of measurement of nasal length, nasal diagonal, tip projection, and upper lip height, and noting transverse upper labial crease in repose and during smiling, before rhinoplasty for preoperative evaluation and after the operation for outcome assessment. Depressor septi nasi muscle treatment should be considered if a decrease in tip projection or upper lip height with smiling or a transverse upper labial crease during smiling is extraordinary or unsightly. Therapeutic, II.

  3. [Perception of asymmetry smile: Attempt to evaluation through Photoshop].

    PubMed

    Diakite, C; Diep, D; Labbe, D

    2016-04-01

    In the labial palliative surgery of facial paralysis, it can persist asymmetry smile. Evaluate the impact of an augmentation or reduction of the commissural course on the perception of a smile anomaly, and determine from which asymmetry threshold, the smile is estimated unsightly. We took a picture of two people with a smile not forced; including one with a "cuspid smile", and the another one with a "Mona Lisa" smile. The pictures obtained were modified by the Photoshop software, to simulate an asymmetry labial smile. The changes were related to the move of the left labial commissure, the left nasolabial furrow, and the left cheek using under-correction and overcorrection, every 4 mm. Three pictures with under-correction and four pictures with over-correction were obtained. These smiles were shown to three groups of five people, which included doctors in smile specialties, doctors in other specialties, and non-doctors. Participants were then asked to indicate on which of the pictures, the smile seemed abnormal. Between -8 mm under-correction, and +8 mm over-correction, the asymmetry of the commissural course does not hinder the perception of smile. In the labial palliative surgery of facial paralysis, in the case of persistent asymmetry, there is a tolerance in the perception of "normality" of smile concerning the amplitude of the commissural course going up to 8 mm of asymmetric with under-correction or over-correction. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  4. Metastatic Vulvar Crohn's Disease—A Rare Case Report and Short Review of Literature

    PubMed Central

    Das, Debajit; Gupta, Bhaskar; Saha, Mahimanjan

    2016-01-01

    Metastatic Crohn's disease (CD), a type of extraintestinal CD may present with gynecological manifestation which causes diagnostic dilemma and needs multidisciplinary approach. Vulvar lesions occur in very small number of cases with CD of which asymmetrical labial swelling and edema is the most common presentation. We report a case of hypertrophic exophytic variety of vulvar CD because of its rarity. PMID:26955098

  5. The Tribolium castaneum ortholog of Sex combs reduced controls dorsal ridge development

    USDA-ARS?s Scientific Manuscript database

    In insects, the boundary between the embryonic head and thorax is formed by the dorsal ridge, a fused structure composed of portions of the maxillary and labial segments. However, the mechanisms that promote development of this unusual structure remain a mystery. In Drosophila, mutations in the Hox ...

  6. Face-Referenced Measurement of Perioral Stiffness and Speech Kinematics in Parkinson's Disease

    ERIC Educational Resources Information Center

    Chu, Shin Ying; Barlow, Steven M.; Lee, Jaehoon

    2015-01-01

    Purpose: Perioral biomechanics, labial kinematics, and associated electromyographic signals were sampled and characterized in individuals with Parkinson's disease (PD) as a function of medication state. Method: Passive perioral stiffness was sampled using the OroSTIFF system in 10 individuals with PD in a medication ON and a medication OFF state…

  7. [Reconstruction of the mandibular symphysis using a revascularized free flap of the scapula. Surgical technic].

    PubMed

    Mayot, D; Perrin, C; Lindas, P; Dron, K

    1993-01-01

    In cases of surgically removed mandibular symphysis malignancies, the bone and mouth floor were reconstructed using osteo-musculo-cutaneous flaps. In our experience, the latter provide the best results. Removed in dorsal decubitus, they allow floor replacement. During the dissection of the tumor site, we also preserve labial and chin structures, which favours a good restoration of phonation and swallowing.

  8. Treatment of mandibular anterior crowding with incisor extraction using lingual orthodontics: a case report.

    PubMed

    Viswanath, Divya; Shetty, Sandeep; Mascarenhas, Rohan; Husain, Akhter

    2010-01-01

    A 20-year-old woman presented with a labially displaced mandibular right central incisor with severe attrition. Her maxillary dentition was well-aligned, and she had a straight profile. The respective central incisor was extracted. Subsequently, all teeth were aligned and the extraction space was closed with 2D lingual brackets. The result was esthetically pleasing.

  9. Interarticulator Coordination in Dysarthria: An X-Ray Microbeam Study

    ERIC Educational Resources Information Center

    Weismer, Gary; Yunusova, Yana; Westbury, John R.

    2003-01-01

    Articulatory discoordination is often said to be an important feature of the speech production disorder in dysarthria, but little experimental work has been done to identify and specify the coordination difficulties. The present study evaluated the coordination of labial and lingual gestures for /u/ production in persons with Parkinson's disease…

  10. Interarticulator Coordination in Dysarthria: An X-Ray Microbeam Study

    ERIC Educational Resources Information Center

    Weismer, Gary; Yunusova, Yana; Westbury, John R.

    2003-01-01

    Articulatory discoordination is often said to be an important feature of the speech production disorder in dysarthria, but little experimental work has been done to identify and specify the coordination difficulties. The present study evaluated the coordination of labial and lingual gestures for /u/ production in persons with Parkinson's disease…

  11. Phonological and Phonetic Asymmetries of Cw Combinations

    ERIC Educational Resources Information Center

    Suh, Yunju

    2009-01-01

    This thesis investigates the relationship between the phonological distribution of Cw combinations, and the acoustic/perceptual distinctiveness between syllables with plain C onsets and with Cw combination onsets. Distributional asymmetries of Cw combinations discussed in this thesis include the avoidance of Cw combinations in the labial consonant…

  12. Towards a Phonetic Explanation for Universal Preferences in Implosives and Ejections.

    ERIC Educational Resources Information Center

    Javkin, Hector

    Two possible explanations based on elementary facts of physics are suggested for the universal preference for place of articulation of implosives and ejectives. Languages show a preference for ejectives in the order: velar, alveolar, and labial while implosives occur most often in the opposite order. A language will only have velar implosives if…

  13. Labio-Patalization in Twi: Contrastive, Quantal, and Organizational Factors Producing an Uncommon Sound.

    ERIC Educational Resources Information Center

    de Jong, Kenneth; Obeng, Samuel Gyasi

    2000-01-01

    Proposes that the typologically uncommon combination of labial and palatal constriction in Twi has arisen from a convergence created by general patterns of coarticulation of consonants and vowels. This convergence has been systematized in a consonantal acoustic dimension partially independent from the original vocalic dimensions of contrast for…

  14. Underlying Phoneme Velar Nasal with Lip Rounding in Hueyapan Nahuatl

    ERIC Educational Resources Information Center

    Campbell, R. Joe

    1976-01-01

    Reasons are given for the idea that Hueyapan (Morelos) Nahuatl has an underlying velar nasal with lip rounding phoneme which never has the surface reflex of a rounded velar nasal allophone, but occurs phonetically as a velar nasal allophone or a labial dental voiced allophone or disappears. (SCC)

  15. Hox proteins coordinate peripodial decapentaplegic expression to direct adult head morphogenesis in Drosophila

    PubMed Central

    Stultz, Brian G.; Park, Sung Yeon; Mortin, Mark A.; Kennison, James A.; Hursh, Deborah A.

    2012-01-01

    The Drosophila BMP, decapentaplegic (dpp), controls morphogenesis of the ventral adult head through expression limited to the lateral peripodial epithelium of the eye-antennal disc by a 3.5 kb enhancer in the 5’ end of the gene. We recovered a 15 bp deletion mutation within this enhancer that identified a homeotic (Hox) response element that is a direct target of labial and the homeotic cofactors homothorax and extradenticle. Expression of labial and homothorax are required for dpp expression in the peripodial epithelium, while the Hox gene Deformed represses labial in this location, thus limiting its expression and indirectly that of dpp to the lateral side of the disc. The expression of these homeodomain genes is in turn regulated by the dpp pathway, as dpp signaling is required for labial expression but represses homothorax. This Hox-BMP regulatory network is limited to the peripodial epithelium of the eye-antennal disc, yet is crucial to the morphogenesis of the head, which fate maps suggest arises primarily from the disc proper, not the peripodial epithelium. Thus Hox/BMP interactions in the peripodial epithelium of the eye-antennal disc contribute inductively to the shape of the external form of the adult Drosophila head. PMID:22824425

  16. Factors affecting self-eruption of displaced permanent maxillary canines.

    PubMed

    Smailienė, Dalia; Sidlauskas, Antanas; Lopatienė, Kristina; Guzevičienė, Vesta; Juodžbalys, Gintaras

    2011-01-01

    The aim of this study was to examine the possibility of the spontaneous eruption of displaced unerupted maxillary canines after the extraction of the deciduous canine and dental arch expansion and to determine the impact of initial canine position on treatment success rate. Materials and METHODS. The study sample included 50 patients (mean age, 13.5 years [SD, 2.2]) with unilaterally displaced unerupted maxillary canines. Deciduous canines were extracted, and the space for displaced canine was created at the beginning of the study. The follow-up period for the spontaneous eruption was 12 months. The initial vertical, horizontal, labio-palatal position and angle of inclination to the midline of the displaced canine were assessed on panoramic radiographs. RESULTS. Only 42% of displaced canines erupted spontaneously within one-year period (52.9% of labially displaced canines and 36.4% of palatally displaced canines). A significant difference of inclination was determined between spontaneously erupted and unerupted teeth in the labially displaced canine group (P<0.01), with no difference in the palatally displaced canine group. The receiver operating characteristic curve analysis showed that the critical angle of inclination for the spontaneous eruption of the retained canine was 20º (sensitivity 0.759; specificity 0.571; P<0.05). The majority of unerupted canines (75.9%) were inclined more than 20º. The initial height of canine was crucial for spontaneous eruption (sensitivity 0.966; specificity 0.81; P<0.001). This was true for both palatal and labial cases. CONCLUSIONS. The initial vertical position of the labially and palatally displaced canines and the inclination of the labially displaced canines were the most important predictors for spontaneous eruption of the cuspid.

  17. [Characteristics of the stomatognathic system of mouth breathing children: anthroposcopic approach].

    PubMed

    Cattoni, Débora Martins; Fernandes, Fernanda Dreux Miranda; Di Francesco, Renata Cantisani; Latorre, Maria do Rosário Dias de Oliveira

    2007-01-01

    the use of anthroposcopy in the assessment of posture and morphology of the stomatognathic system of mouth breathing children. to describe the postural and morphologic characteristics of the stomatognathic system of mouth breathing children, according to age. participants were 100 children, of both genders, with ages ranging from 7 to 11 years and 11 months, leukoderms, in mixed dentition and with the diagnosis of mouth breathing. The investigated postural and morphologic characteristics of the stomatognathic system were labial and lingual resting position, possibility of labial occlusion, hyperfunction of the mentalis muscle during labial occlusion, bite and morphology of the lower lip, cheeks and hard palate, using the anthroposcopy methodology. the results referring to the characterization of the studied population, according to the most frequent otorhinolaryngologic diagnosis, was of enlarged pharyngeal and palatine tonsils. A statistically significant difference was found between the percentages of each otorhinolaryngologic diagnosis, according to age. The results of the characteristics of the stomatognathic system indicated that the most common aspects in the studied sample were: half-open lips when in the resting position, tongue lowered on the mouth's floor in the resting position, possibility of labial occlusion, hyperfunction of the mentalis muscle during labial occlusion, alterations of bite, labioverted, symmetry of the cheeks and alteration of the hard palate. All of the studied characteristics presented the same frequency with the increase in age, with no statistically significant difference. mouth breathing children presented pathologic adaptations in the postural and morphological characteristics of the stomatognathic system. This suggests the importance of early diagnosis in order to avoid orofacial alterations.

  18. [Relationship between the nutritional status and the oral function among community-dwelling dependent elderly persons].

    PubMed

    Morisaki, Naoko; Miura, Hiroko; Hara, Shuichi

    2015-01-01

    We herein examined the relationship between the nutritional status and the oral function among community-dwelling dependent elderly persons. The subjects included 218 community-dwelling dependent elderly persons. The data were collected via questionnaires, including information regarding age, sex, the level of care required, nutritional status and swallowing function. We used the Mini Nutritional Assessment-Short Form (MNA-SF) to measure the nutritional status and the Dysphagia Risk Assessment for the Community-dwelling Elderly (DRACE) to evaluate the swallowing function. The tongue pressure and the labial closure force were measured using a tongue pressure measurement system (JMS Co. Ltd., Hiroshima, Japan) and the Lip de Cum (Cosmo-Instruments Co, Ltd, Tokyo, Japan). The mean MNA-SF score was 10.07±2.58. The mean DRACE score was 4.39±3.80. The mean tongue pressure was 23.89±10.61 kPa. The mean labial closure force was 10.17±6.04 N. The results of bivariate regression analyses showed that there was a poor correlation between the MNA-SF and the DRACE, tongue pressure and labial closure force. Furthermore, the multiple regression analysis with the MNA-SF as the dependent variable revealed a correlation between the DRACE and labial closure force (p<0.01, R(2)=0.02). Our results suggest that the nutritional status is significantly related to the swallowing function and labial closure force among community-dwelling dependent elderly persons.

  19. Plate-like permanent dental laminae of upper jaw dentition in adult gobiid fish, Sicyopterus japonicus.

    PubMed

    Moriyama, Keita; Watanabe, Shun; Iida, Midori; Sahara, Noriyuki

    2010-04-01

    Sicyopterus japonicus (Teleostei, Gobiidae) possesses a unique upper jaw dentition different from that known for any other teleosts. In the adults, many (up to 30) replacement teeth, from initiation to attachment, are arranged orderly in a semicircular-like strand within a capsule of connective tissue on the labial side of each premaxillary bone. We have applied histological, ultrastructural, and three-dimensional imaging from serial sections to obtain insights into the distribution and morphological features of the dental lamina in the upper jaw dentition of adult S. japonicus. The adult fish has numerous permanent dental laminae, each of which is an infolding of the oral epithelium at the labial side of the functional tooth and forms a thin plate-like structure with a wavy contour. All replacement teeth of a semicircular-like strand are connected to the plate-like dental lamina by the outer dental epithelium and form a tooth family; neighboring tooth families are completely separated from each other. The new tooth germ directly buds off from the ventro-labial margin of the dental lamina, whereas no distinct free end of the dental lamina is present, even adjacent to this region. Cell proliferation concentrated at the ventro-labial margin of the dental lamina suggests that this region is the site for repeated tooth initiation. During tooth development, the replacement tooth migrates along a semicircular-like strand and eventually erupts through the dental lamina into the oral epithelium at the labial side of the functional tooth. This unique thin plate-like permanent dental lamina and the semicircular-like strand of replacement teeth in the upper jaw dentition of adult S. japonicus probably evolved as a dental adaptation related to the rapid replacement of teeth dictated by the specialized feeding habit of this algae-scraping fish.

  20. Variations of midfacial soft-tissue thickness in subjects aged between 6 and 18years for the reconstruction of the profile: A study on an Italian sample.

    PubMed

    Gibelli, Daniele; Collini, Federica; Porta, Davide; Zago, Matteo; Dolci, Claudia; Cattaneo, Cristina; Sforza, Chiarella

    2016-09-01

    Facial approximation techniques used in forensic anthropology are based on soft-tissue thickness databases. However most of articles deal with adult populations, and very few studies were conducted on minors. This study aims at providing data concerning facial thickness for George reconstruction, preliminary to the 3D facial approximation. Diagnostic cephalometric X-ray films were obtained from 222 healthy Caucasoid children (91 boys and 131 girls), aged between 6 and 18years, treated in a Department of Orthodontics of Northern Italy. After setting the Frankfurt plane horizontal, 14 measurements were taken at the mid-facial landmarks: supraglabella, glabella, nasion, nasale, subnasale, superior labial sulcus, labrale superius, stomion, labrale inferius, inferior labial sulcus, suprapogonion, pogonion, gnathion, menton. Mean and standard deviation of soft-tissues thickness at each point were calculated. A two-way analysis of variance (ANOVA) was performed to test the modifications of facial parameters with age and sex (p<0.01). The results demonstrated that there is an increase in tissue thickness as individuals grow; in most occasions, males showed thicker soft tissues than females of the same age, especially after the adolescent growth spurt. Facial thicknesses at subnasale, superior labial sulcus, labrale superius, labrale inferius, inferior labial sulcus, suprapogonion, pogonion and gnathion significantly modified with age, whereas the same parameters at subnasale, superior labial sulcus, labrale superius, labrale inferius, stomion and suprapogonion were significantly sexually dimorphic. In addition, a database for soft-tissue thicknesses in children aged between 6 and 18years was created, which may be of interest in cases of facial approximation of Italian minors.

  1. Adolescent Foley catheter technique for visualizing hymenal injuries in adolescent sexual assault.

    PubMed

    Jones, Jeffrey S; Dunnuck, Chris; Rossman, Linda; Wynn, Barbara N; Genco, Michael

    2003-09-01

    To determine the usefulness of the Foley catheter balloon technique for visualizing injuries of the estrogenized hymen in adolescent sexual assault victims compared with supine labial traction. A prospective clinical trial of 20 adolescent (age 13-16 years old) victims of sexual assault evaluated at a free-standing Nurse Examiner Clinic was conducted over a four-month study period. The clinic, affiliated with an emergency medicine residency program, is staffed by registered nurses who have been specially trained to perform medicolegal examinations using colposcopy with digital imaging. The Foley catheter technique uses an inflated balloon in the distal vaginal vault to expand the estrogenized hymen to its full capacity so that the edge may be readily visualized for signs of trauma. The Foley technique was compared with gross inspection, using supine labial traction, to photodocument hymenal abnormalities. Photographs of the hymen were obtained using the labial traction technique and then with the Foley technique. Three emergency physicians independently examined each pair of photographs with high interrater agreement for the presence of injury (kappa = 0.88). Twenty adolescent sexual assault victims volunteered for the study; mean age was 14.8 years. Gross inspection of the hymen using supine labial traction identified hymenal injuries in three patients (15%). Use of the Foley catheter balloon technique allowed identification of hymenal abnormalities in nine additional cases (60%). The common injuries to the hymen included lacerations (30%), followed by ecchymosis and abrasions. One patient (5%) voiced discomfort (mild pressure sensation) during inflation of the balloon. The Foley catheter balloon technique is a simple method allowing improved photodocumentation of hymenal trauma in adolescent sexual assault victims compared with supine labial traction.

  2. Prevalence and intensity of pathologies induced by the toxic dinoflagellate, Heterocapsa circularisquama, in the Mediterranean mussel, Mytilus galloprovincialis.

    PubMed

    Basti, Leila; Endo, Makoto; Segawa, Susumu; Shumway, Sandra E; Tanaka, Yuji; Nagai, Satoshi

    2015-06-01

    The harmful dinoflagellate, Heterocapsa circularisquama, has been causing mass mortalities of bivalve molluscs in Japan, at relatively low cell densities. Although several studies have been conducted to determine the toxicity mechanisms, the specific cause of death is still unclear. In a previous study, in our laboratory, it was shown that H. circularisquama (10(3) cells ml(-1)) caused extensive cytotoxicity in the gills of short-neck clams, Ruditapes philippinarum. In the present study, Mediterranean mussels, Mytilus galloprovincialis, were exposed to H. circularisquama at four cell densities (5, 50, 500, 10(3) cells ml(-1)), three temperatures (15, 20, and 25°C), and three exposure durations (3, 24, and 48 h), and the pathologies in nine organs (gills, labial palps, mantle, hepatopancreas, stomach, intestines, exhalant siphon, adductor muscles, and foot) were assessed. Foot, adductor muscles, and exhalent siphons of mussels were not affected; however, 16 inflammatory (hemocytic infiltration and aggregation, diapedesis, hyperplasia, hypertrophy, edema, melanization, and firbrosis) and degenerative (thrombus, thrombosed edema, cilia matting and exfoliation, epithelial desquamation, atrophy, and necrosis) pathologies were identified in the gills, labial palps, mantle, hepatopancreas, stomach, and intestines. The total prevalence and total intensity of pathology in each individual mussel, and the prevalence and intensity of pathology in each organ increased significantly with increased cell density, exposure duration, and temperature. The prevalence of pathology was the highest in gills, followed by the prevalence in labial palps, mantle, stomach, and intestines. Pathology was least prevalent in the hepatopancreas. The intensity of pathology was the highest in the gills, followed by the labial palps and mantle, the stomach and intestines, and the hepatopancreas. This detailed quantitative histopathological study demonstrates that exposure to H. circularisquama

  3. Evaluation of three different tooth preparation techniques for metal ceramic crowns by comparing preparation depths: An in vitro study

    PubMed Central

    Ram, Hardik K.; Shah, Rupal J.; Agrawal, Hemal S.

    2015-01-01

    Aim: To determine the effect of three different tooth preparation techniques had on operator's ability to appropriately and consistently prepare teeth for metal ceramic crowns. Materials and Methods: Ninety maxillary left central incisor typodont teeth were allocated to three equal groups (A, B and C) of thirty and mounted in standard working model one at a time. A freehand approach was used to prepare the teeth in Group A, which acted as a control. Groups B and C were prepared with the assistance of silicon index and suitable depth gauge burs, respectively. A silicon index of unprepared teeth, into which contrasting colored silicon injected to occupy the space created by tooth preparation, was sectioned in the midline. Images of sectioned index were captured with optical microscope attached to a personal computer. A calibrated image analysis software was used to measure the depth of preparation (in millimeters) at five points (labial-cervical, mid-labial, incisal, mid-palatal and palatal cervical) on two occasions. These results were pooled and averaged to give a mean labial, incisal and palatal preparation depths in mm. The data were analyzed by one-way analysis of variance and Scheffe's post-hoc statistical test. Results: The mean depth of labial and incisal preparation for Groups A, B and C was 1.23 and 1.72 mm, 1.45 and 1.96 mm, 1.47 and 1.95 mm, respectively. The difference between the groups’ labial preparation depth was significant as well as the difference between groups’ incisal preparation depth. The mean palatal preparation was 0.46 mm for Group A, 0.54 mm for Group B and 0.59 mm for Group C. Conclusion: Teeth preparation for metal ceramic crowns without any assistance can lead to under-preparation of labial and incisal surface. Clinical Significance: Whenever possible, considerable importance should be given to the use of index or depth gauge burs for preparing teeth for receiving metal ceramic crowns. PMID:26929505

  4. Anesthetic efficacy of an infiltration in mandibular anterior teeth following an inferior alveolar nerve block.

    PubMed Central

    Clark, Kenneth; Reader, Al; Beck, Mike; Meyers, William J.

    2002-01-01

    The purpose of this prospective, randomized, blinded study was to measure the degree of pulpal anesthesia obtained with an inferior alveolar nerve (IAN) block followed by an infiltration in mandibular anterior teeth. Through use of a repeated-measures design, 40 patients randomly received 3 injection combinations at 3 separate appointments: an IAN block followed by a mock lingual infiltration and a mock labial infiltration, an IAN block followed by a mock lingual infiltration and a labial infiltration, and an IAN block followed by a mock labial infiltration and a lingual infiltration. Each IAN block used 3.6 mL of 2% lidocaine with 1:100,000 epinephrine, and each infiltration used 1.8 mL of 2% lidocaine with 1:100,000 epinephrine administered over the lateral incisor apex. Mandibular anterior teeth were blindly pulp tested at 2-minute cycles for 60 minutes following the IAN-infiltration injections. No response from the patient to the maximum output (80 reading) of the pulp tester was used as the criterion for pulpal anesthesia. Anesthesia was considered successful when 2 consecutive 80 readings were obtained within 15 minutes and the 80 reading was sustained for 60 minutes. Anesthesia was considered a failure if 2 consecutive 80 readings were not obtained during the 60 minutes. The results of this study showed that 100% of the patients had lip numbness with all IAN blocks. For the lateral incisor, the success rate of the IAN block alone was 40% and the failure rate was 30%. For the IAN block plus labial infiltration, the success rate was 62% and the failure rate was 12% for the lateral incisor. There was a significant difference (P < .05) between the IAN block alone and the IAN block plus labial infiltration. In conclusion, a labial infiltration, over the lateral incisor apex, of 1.8 mL of 2% lidocaine with 1:100,000 epinephrine following an IAN block significantly improved pulpal anesthesia for the lateral incisor compared with the IAN block alone. PMID:15384292

  5. Distribution of pimonidazole and RSU 1069 in tumour and normal tissues.

    PubMed

    Cobb, L M; Nolan, J; Butler, S A

    1990-12-01

    The tritium-labelled analogues of pimonidazole and RSU 1069 were injected into mice bearing the KHT murine sarcoma which has a hypoxic cell fraction of approximately 10%. The distribution of activity at 24 h was recorded using autoradiography and measurement of tissue activity. Autoradiographs with both drugs showed high activity in particular cells within tumour, eye (melanin-associated cells), eyelid (Meibomian gland), liver (centrilobular area), skin (sebaceous gland and melanin), stomach (squamous area), footpad, oesophagus, labial gland, Zymbal's gland, preputial gland, parotid gland (intralobular ducts) and airway epithelium. These tissues had previously been identified as sites of binding of misonidazole. The measurement of total tissue radioactivity showed significantly higher activity in liver, eyelid (Meibomian gland), oesophageal lining, kidney and labial gland than was found in the tumour.

  6. Distribution of pimonidazole and RSU 1069 in tumour and normal tissues.

    PubMed Central

    Cobb, L. M.; Nolan, J.; Butler, S. A.

    1990-01-01

    The tritium-labelled analogues of pimonidazole and RSU 1069 were injected into mice bearing the KHT murine sarcoma which has a hypoxic cell fraction of approximately 10%. The distribution of activity at 24 h was recorded using autoradiography and measurement of tissue activity. Autoradiographs with both drugs showed high activity in particular cells within tumour, eye (melanin-associated cells), eyelid (Meibomian gland), liver (centrilobular area), skin (sebaceous gland and melanin), stomach (squamous area), footpad, oesophagus, labial gland, Zymbal's gland, preputial gland, parotid gland (intralobular ducts) and airway epithelium. These tissues had previously been identified as sites of binding of misonidazole. The measurement of total tissue radioactivity showed significantly higher activity in liver, eyelid (Meibomian gland), oesophageal lining, kidney and labial gland than was found in the tumour. Images Figure 1 Figure 2 PMID:2257219

  7. Vascular mapping of the face: B-mode and doppler ultrasonography study.

    PubMed

    Tucunduva, M-J; Tucunduva-Neto, R; Saieg, M; Costa, A-L; de Freitas, C

    2016-03-01

    To analyze the face vascularization pattern using B-mode and Doppler ultrasonography, and also propose an arterial vessel mapping. The investigation was performed on 20 ultrasonography exams of facial vessels through linear and endocavitary transducers. We analyzed and determined the average values for diameters, peak systolic velocity and resistive index of the following arteries: external carotid, lingual, deep lingual, sublingual, facial, submental, inferior labial, superior labial, angular, maxillary inferior alveolar, mental, buccal, greater palatine, infraorbital, superficial temporal, transverse facial and frontal. Data was obtained allowing the analysis of the tissue hemodynamics. We were able to map the vascularization of the face and it was possible to access three arteries of small diameter (0,60mm angular artery; 0,55mm greater palatine artery; 0,45mm infraorbital artery). The results presented in this article are valid tool supporting the non-invasive mapping of facial vascularization.

  8. Description of Sclerorhabditis miniata n. sp. and First Description of Male of Diploscapter coronatus Cobb, 1913 (Nematoda: Rhabditidae)

    PubMed Central

    Shah, Ali Asghar

    2015-01-01

    A population of Sclerorhabditis miniata n. sp. is described and illustrated from Poonch district of Jammu and Kashmir State, India. The new species is characterized by small body size, with an annulated cuticle, offset labial region, crown shaped, strongly sclerotized lips, thin lateral lips, membranous, stegostom without glottoid apparatus, cheilostom rod shaped, sclerotized, spicules free, strong and thick, gubernaculum simple, bent proximally, bursa open, peloderan with seven pairs of bursal papillae in 1+1/1+1+2+1 pattern. The males of Diploscapter coronatus are described for the first time. They are usually smaller than the females and have labial region similar to females. Spicules separate, with a small dorsal velum, gubernaculum simple, almost straight, bursa open, pseudopeloderan with seven pairs of bursal papillae in 1+1/1+2+1+1 pattern. PMID:26170478

  9. On the origin of internal structure of word forms.

    PubMed

    MacNeilage, P F; Davis, B L

    2000-04-21

    This study shows that a corpus of proto-word forms shares four sequential sound patterns with words of modern languages and the first words of infants. Three of the patterns involve intrasyllabic consonant-vowel (CV) co-occurrence: labial (lip) consonants with central vowels, coronal (tongue front) consonants with front vowels, and dorsal (tongue back) consonants with back vowels. The fourth pattern is an intersyllabic preference for initiating words with a labial consonant-vowel-coronal consonant sequence (LC). The CV effects may be primarily biomechanically motivated. The LC effect may be self-organizational, with multivariate causality. The findings support the hypothesis that these four patterns were basic to the origin of words.

  10. A customized zirconia abutment design combined with a CAD/CAM laminate veneer: a clinical report.

    PubMed

    Ertürk, Burcu Kanat; Çömlekoğlu, M Erhan; Çömlekoğlu, Mine Dündar; Aladağ, Akιn; Güngör, Mehmet Ali

    2015-01-01

    An alternative prosthetic treatment approach for single implants in the maxillary esthetic zone with an improper implant axis, limited interocclusal distance, inadequate abutment retention, and screw holes located at the labial surface is presented in this clinical report. The gingiva and soft tissues were contoured with provisional composite restorations to mimic the emergence profile of lateral incisors. Prefabricated zirconia abutments were customized with laminate veneer preparations by appropriate ceramic build-up with reference from the reshaped gingiva to avoid labiolingual overcontour. The laminate veneers were fabricated by computer-aided design/ computer-assisted manufacture to cover the screw hole of the angulated abutment at the labial surface. Preliminary results revealed improvement in esthetics; however, long-term clinical follow-up should be performed.

  11. Two new species of Parasaveljevia Wieser, 1953 (Thoracostomopsidae, Nematoda) from Argentinean coasts (Chubut, Argentina).

    PubMed

    Pastor, Catalina; Lo Russo, Virginia; Villares, Gabriela

    2015-10-06

    Two new Parasavaljevia species are described, one from Puerto Madryn, and one from El Límite beach, San Jorge Gulf, Chubut Province, Argentina. The two species are characterised by a combination of characters. Parasavaljevia uncinoa n. sp. is characterised by having a long rectangular cirrus, positioned at the level of the inner labial setae, rectangular mandibles with prominent lateral hooks bearing denticles in three lines of nine each, and six cephalic setae of the same length, inserted at the anterior end of a small head capsule. Parasavaljevia limitense n. sp. is characterized by having a cirrus posterior positioned, between the labial and cephalic setae, rectangular-arched mandibles bearing denticles in five lines of ten each in a gradient of sizes; a small buccal cavity, small cephalic capsule and abundant cervical setae (4+10). An emendation of the genus diagnosis and a new key are given and discussed.

  12. Examination of the reflection properties of sloping terminations to organ pipes.

    PubMed

    Rucz, Péter; Dolde, Kai; Kuang, Wei; Angster, Judit; Miklós, András

    2016-12-01

    The sound characteristics of both labial and lingual organ pipes are affected to a great extent by the reflection properties of the resonators. In this paper, the reflection properties of sloped pipe terminations are examined and the possible applications in organ building practice are investigated. Sloped shallots of reed organ pipes with different termination angles are of particular interest in this study. For the examination of the reflection properties two different approaches are applied. Sound pulse reflection measurements on model geometries provide experimental data in the time domain, while finite element simulations yield reflection coefficients in the frequency domain. These two remarkably different approaches are shown to provide consistent results for all examined geometries. Laboratory measurements performed on experimental labial pipes and "Trompete" (trumpet) shallots demonstrate some of the effects of sloped terminations on the sound of organ pipes and validate the applicability of the results obtained by the model measurements and simulations.

  13. Evaluation of margin angles of collarless metal ceramic restorations.

    PubMed

    Dalvit, Deborah L; Parker, M Harry; Cameron, Stephen M; Hawkins, M Chad; Agar, John R; Brousseau, J Stephen

    2004-01-01

    This study was designed to measure the porcelain margin angles of completed collarless metal ceramic restorations and determine if these angles correspond to the most frequently recommended porcelain margin angle of 90 degrees. A sample of 99 metal ceramic restorations with porcelain labial margins were evaluated. A 1.0 mm slice taken from the midfacial impression of each restoration was evaluated by tooth location with a stereomaster microscope and the angle of the labial porcelain margin was calculated. The comparison of margin angles by tooth location showed no statistical difference between the groups. Comparison of the average margin angle with the most suggested 90-degree angle was analyzed with a One-Sample t-test and found to be statistically significant (p = 0.000). Although the majority of dental schools teach the shoulder preparation for collarless metal ceramic restorations, only 43% of the restorations measured fell within 10 degrees of this standard.

  14. A tongue for all seasons: extreme phenotypic flexibility in salamandrid newts.

    PubMed

    Heiss, Egon; Handschuh, Stephan; Aerts, Peter; Van Wassenbergh, Sam

    2017-04-21

    Many organisms faced with seasonally fluctuating abiotic and biotic conditions respond by altering their phenotype to account for the demands of environmental changes. Here we discovered that newts, which switch seasonally between an aquatic and terrestrial lifestyle, grow a complex adhesive system on their tongue pad consisting of slender lingual papillae and mucus-producing cells to increase the efficiency of prey capture as they move from water onto land. The adhesive system is reduced again as newts switch back to their aquatic stage, where they use suction to capture prey. As suction performance is also enhanced seasonally by reshaping of the mouth due to the growth of labial lobes, our results show that newts are exceptional in exhibiting phenotypic flexibility in two alternating components (i.e. tongue pad and labial lobes) within a single functional system, and suggest that this form of phenotypic flexibility demands complex genetic regulation.

  15. A survey of conservation of sea spider and Drosophila Hox protein activities.

    PubMed

    Saadaoui, Mehdi; Litim-Mecheri, Isma; Macchi, Meiggie; Graba, Yacine; Maurel-Zaffran, Corinne

    2015-11-01

    Hox proteins have well-established functions in development and evolution, controlling the final morphology of bilaterian animals. The common phylogenetic origin of Hox proteins and the associated evolutionary diversification of protein sequences provide a unique framework to explore the relationship between changes in protein sequence and function. In this study, we aimed at questioning how sequence variation within arthropod Hox proteins influences function. This was achieved by exploring the functional impact of sequence conservation/divergence of the Hox genes, labial, Sex comb reduced, Deformed, Ultrabithorax and abdominalA from two distant arthropods, the sea spider and the well-studied Drosophila. Results highlight a correlation between sequence conservation within the homeodomain and the degree of functional conservation, and identify a novel functional domain in the Labial protein.

  16. Vulvovaginitis and other common vulvar disorders in children.

    PubMed

    Rome, Ellen S

    2012-01-01

    Vulvovaginitis, labial adhesions, and other vulvar disorders occur commonly in children and can provoke high anxiety in both the parent and child. Performed correctly, the pediatric gynecologic examination can diagnose and treat, educate and reassure both parent and child. This examination requires patience, sensitivity, direct communication with the child as well as with the parent, and an open manner that inspires trust in both parties to manage a potentially anxiety-provoking situation. This chapter will review common vulvar disorders, including vulvovaginitis, lichen sclerosis et atrophicus, bubble bath vaginitis, labial adhesions, urethral prolapse, and other common problems. A discussion of childhood sexual abuse is beyond the scope of this chapter, with appropriate references available elsewhere. Practical pearls will be offered to make this exam easy for the primary care clinician and/or subspecialist.

  17. Dilaceration of maxillary central incisor: a literature review.

    PubMed

    Topouzelis, Nikolaos; Tsaousoglou, Phoebus; Pisoka, Vasiliki; Zouloumis, Lampros

    2010-10-01

    The main purpose of this review is to present the aetiological factors and the mechanism that cause dilaceration of the maxillary central incisors. In early developmental stages, the permanent tooth germ of the maxillary incisor is situated palatally and superiorly to the apex of the primary incisor and gradually changes direction in a labial direction with its crown coming closer to the resorbing primary root. For reasons of this close relationship between the permanent tooth germ and the apex of the primary incisor, it is believed that an acute trauma to the primary predecessor can cause dilaceration of the long axis of the permanent successor. Clinically, dilaceration can be revealed by palpation high in the labial sulcus or in the hard palate, while its radiographic view is characteristic. The therapeutic approach to the dilacerated maxillary central incisors has to be carefully planned and needs the cooperation of several specialities to attain the final objective. © 2010 John Wiley & Sons A/S.

  18. Female genital mutilation - postcircumcision vulval complications in Nigerians.

    PubMed

    Adekunle, A O; Fakokunde, F A; Odukogbe, A A; Fawole, A O

    1999-11-01

    Female genital mutilation is a cultural practice that can adversely affect the health of women. Vulval complications of female circumcision in 39 patients managed at the University College Hospital, Ibadan, Nigeria over a period of 10 years were reviewed. The complications were: labial adhesions of varying degrees (51.3%) and clitoral retention cysts (48.7%). However, both types of complications occurred concurrently in two (5.1%) patients. All patients were treated surgically with good outcome. The only immediate complication of treatment was secondary haemorrhage in one patient with clitoral cyst. Regrettably, one patient with labial adhesion required a repeat surgical procedure 2 months later. The histological examination of all the retention cysts revealed epidermal inclusion cysts. Emphasising the reproductive health implications of female genital mutilation may prove an effective strategy towards eradication of the practice.

  19. Clinical limitations of Invisalign.

    PubMed

    Phan, Xiem; Ling, Paul H

    2007-04-01

    Adult patients seeking orthodontic treatment are increasingly motivated by esthetic considerations. The majority of these patients reject wearing labial fixed appliances and are looking instead to more esthetic treatment options, including lingual orthodontics and Invisalign appliances. Since Align Technology introduced the Invisalign appliance in 1999 in an extensive public campaign, the appliance has gained tremendous attention from adult patients and dental professionals. The transparency of the Invisalign appliance enhances its esthetic appeal for those adult patients who are averse to wearing conventional labial fixed orthodontic appliances. Although guidelines about the types of malocclusions that this technique can treat exist, few clinical studies have assessed the effectiveness of the appliance. A few recent studies have outlined some of the limitations associated with this technique that clinicians should recognize early before choosing treatment options.

  20. Evemphyron sinense, a new genus and species infesting legume seedpods in China (Coleoptera, Attelabidae, Rhynchitinae)

    PubMed Central

    Lv, Xiangyang; Alonso-Zarazaga, Miguel A.; Xiao, Zhishu; Wang, Zhiliang; Zhang, Runzhi

    2016-01-01

    Abstract A new genus Evemphyron Alonso-Zarazaga, Lv & Wang, gen. n., belonging to Attelabidae Rhynchitinae, is described. Its single species, Evemphyron sinense Alonso-Zarazaga, Lv & Wang, sp. n., was reared from larvae found inside seed pods of the legume Callerya dielsiana (Fabaceae, Millettieae) in Sichuan Province (China). The species is figured and placed in the Deporaini because of the presence of minute labial palpi, the strongly crescentic apex of the postmentum, and the apodemes of male IX sternite and female VIII sternite curved sinistro-anterially near their cephalic end. It shows 3-segmented labial palpi and male sex patches on the procoxae, characters that suggest a basal position in the tribe. PMID:27408602

  1. Multilobed mesiodens: a supernumerary tooth with unusual morphology.

    PubMed

    Dave, Bhavna; Patel, Jalark; Swadas, Milan; Mallikarjuna, Rachappa

    2013-02-06

    An 8-year-old boy came with a chief complaint of an abnormally shaped tooth situated in upper front teeth region. On examination a supernumerary tooth with multiple lobes was present palatally to the maxillary right permanent central incisor. The morphology of the tooth crown was found to be unusual due to the presence of five lobes in the crown portion. Because of the supernumerary tooth, the permanent right central incisor was displaced labially. Radiographic examination showed a completely formed supernumerary tooth with dilacerated root. On the basis of clinical and radiographic examination, the supernumerary tooth was diagnosed as multilobed mesiodens. Since patient expressed dissatisfaction with the presence of supernumerary tooth, it was decided to extract this mesiodens followed by orthodontic treatment for alignment of labially placed maxillary right permanent central incisor.

  2. Multilobed mesiodens: a supernumerary tooth with unusual morphology

    PubMed Central

    Dave, Bhavna; Patel, Jalark; Swadas, Milan; Mallikarjuna, Rachappa

    2013-01-01

    An 8-year-old boy came with a chief complaint of an abnormally shaped tooth situated in upper front teeth region. On examination a supernumerary tooth with multiple lobes was present palatally to the maxillary right permanent central incisor. The morphology of the tooth crown was found to be unusual due to the presence of five lobes in the crown portion. Because of the supernumerary tooth, the permanent right central incisor was displaced labially. Radiographic examination showed a completely formed supernumerary tooth with dilacerated root. On the basis of clinical and radiographic examination, the supernumerary tooth was diagnosed as multilobed mesiodens. Since patient expressed dissatisfaction with the presence of supernumerary tooth, it was decided to extract this mesiodens followed by orthodontic treatment for alignment of labially placed maxillary right permanent central incisor. PMID:23391956

  3. Transpositional flap technique for mandibular vestibuloplasty.

    PubMed

    Wessberg, G A; Hill, S C; Epker, B N

    1979-06-01

    Various surgical techniques for a mandibular vestibuloplasty have been advocated. A transpositional labial flap technique used by us for 23 patients since May 1976, and based on a procedure described by Edlan, has been presented with results of nine-month follow-up examinations of six patients. Clinical, radiographic, and histological evaluations completed at three-month intervals showed that this transpositional vestibuloplasty compared favorably with other similar techniques in postoperative time of healing, condition of attached mucosa, stability of increased vestibular depth, and amount of resorption of labial bone. Advantages of this procedure over other mandibular vestibuloplasty techniques are its simplicity, low morbidity, decreased operating time, feasibility of use of local anesthesia and conscious sedation on an outpatient basis, and elimination of the need for a graft. The disadvantage of the procedure is that it requires healthy preexisting vestibular mucosa for optimal results.

  4. Evaluation of cutaneous sensibility on infraorbital nerve area.

    PubMed

    Fogaça, Walfredo Cherubini; Sturtz, Gustavo P; Surjan, Rodrigo Canada T; Ferreira, Marcus Castro

    2005-11-01

    Normal facial sensibility on the area of the infraorbital nerve was determined in 24 healthy subjects. The measurement of two points discrimination distance and the evaluation of cutaneous pressure threshold were assessed on both sides on the zygomatic, paranasal, and superior labial skin. Cutaneous sensibility varied from region to region but was consistent from one normal individual to another. Cutaneous sensibility of the superior labial skin was more accurate than zygomatic and paranasal skin in all tests. Sex and dominant sides did not have significant influence on the results. The measurement of two point discrimination distance and the evaluation of cutaneous pressure threshold provided reliable and reproducible data that can be used as a standard to determine facial cutaneous sensibility.

  5. The exaptation of manual dexterity for articulate speech: an electromyogram investigation.

    PubMed

    Higginbotham, David R; Isaak, Matthew I; Domingue, James N

    2008-04-01

    Electromyogram recordings revealed a concurrent contraction of the orbicularis oris, the primary articulator for bilabial stops, when participants executed a precision grip contracting the abductor pollicis brevis, a point motor act contracting the extensor indicis proprius or a curl motor act contracting the flexor sublimis digitorum (FDS). In contrast, the concurrent contraction of several facial muscles not directly involved in labial articulation was not observed during these acts. The results converge both with observations of sympathetic hand and mouth activity among nonhuman primates and prelinguistic human infants and with demonstrations of the influence of grasping on labial articulation in adult humans (e.g., Gentilucci et al., J Neurophysiol 86, 1685-1699, 2001). The findings are also consistent with theories suggesting the transition from gestural to verbal, articulate communication systems may be subserved by the properties of the human equivalent of monkey F5 mirror and canonical neurons located in Broca's area.

  6. A new species of Dudgeodes Sartori, 2008 (Ephemeroptera: Teloganodidae) from Thailand.

    PubMed

    Martynov, Alexander V; Palatov, Dmitry M; Boonsoong, Boonsatien

    2016-06-13

    A new species of the genus Dudgeodes Sartori, 2008 is described from Thailand. It is the first representative of the genus reported from this country. The species is described based on mature nymphs. Dudgeodes romani sp. nov. differs from other species of the genus by the length of antennae; coloration of male eyes; shape of abdominal median tubercles; features of the tarsal claws, forefemora, gills and segments of the labial palps, and by chaetotaxy.

  7. Effect of l-dopa on speech in Parkinsonism 1

    PubMed Central

    Leanderson, R.; Meyerson, B. A.; Persson, A.

    1971-01-01

    The articulatory function of the labial musculature has been investigated electromyographically before and after treatment with l-dopa in patients with Parkinsonism who had dysarthria. Before medication the EMG traces generally showed a constant, abnormally increased, tonic activity, together with disturbed reciprocal innervation, which impaired the articulatory activity. After medication the tonic hyperactivity was reduced and the reciprocal innervation re-established. This normalization of the EMG articulatory pattern was paralleled by an improvement of the dysarthria. PMID:5158782

  8. Minor salivary glands function is decreased in hyposalivation-related diseases.

    PubMed

    Wang, Zhen; Li, Wei; Hong, Xia; Su, Jia-Zeng; Hua, Hong; Peng, Xin; Lv, Lan; Yu, Guang-Yan

    2016-09-01

    The aim of this cross-sectional study was to investigate the relationship between minor salivary gland (MSG) flow rates and oral dryness degrees in patients with xerostomia induced by primary Sjögren's syndrome (pSS), IgG4-related sialadenitis (IgG4-RS), radiation therapy-induced dry mouth (RTDM), or Steven-Johnson syndrome (SJS). 160 patients with pSS, IgG4-RS, RTDM, or SJS and their age- and sex-matched healthy control subjects were enrolled. The whole saliva flow rates and MSG flow rates were measured in four locations, including the upper labial, lower labial, buccal, and palatal mucosae. The degree of oral dryness was assessed in patient groups using the summated xerostomia inventory (SXI). The flow rates of whole saliva and most MSGs in patient groups were significantly lower than the flow rates in healthy control groups (P<0.05). The mean relative percentage of decrease in saliva flow rates was smaller in MSGs than in whole saliva in patient groups (P<0.05), indicating that these disorders have less impact on MSGs. Among the four MSG locations (the upper labial, lower labial, buccal, and palatal), buccal glands showed the highest flow rates in patient groups (P<0.05). SXI scores were significantly higher in pSS and RTDM patients than in IgG4-RS and SJS patients (P<0.05). The degree of xerostomia varied among different patient groups (P<0.05) and there was no clear correlation between MSG flow rates and SXI scores (P>0.05). MSG function is significantly reduced in pSS, RTDM, IgG4-RS, and SJS patients, but this reduction is more pronounced in the major salivary glands. Copyright © 2016. Published by Elsevier Ltd.

  9. Oral Manifestations of Tropical Infectious Diseases of Central and South America. Part II. Bacterial and Mycotic Infections.

    DTIC Science & Technology

    1979-05-24

    characteristic facial deformity called “gangosa” results from destruc- tive involvement of the maxillary nasal processes and hard palate and • heals...become ulcerative and ultimatel y hea l with fibrosis and cicatrization . Lesions usuall y invo l ve the u ps , labial and bucca l mucosa , tongue...ulcerous process which spreads over the adjacent g ing iva and is covered • by a pseudomemb rane. Furthe rmore , patients

  10. Description of Distorhabditis poonchiana n. gen., n. sp. (Nematoda: Rhabditidae) from Jammu and Kashmir, India

    PubMed Central

    Shah, Ali Asghar; Vaid, Shavish; Hussain, Abid; Ahmad, Rakeeb

    2015-01-01

    Distorhabditis poonchiana n. gen., n. sp. from humus in Jammu and Kashmir, India, is described and illustrated. The new genus is characterized by a small body; slightly setoff labial region; long tubular gymnostom; prominently cuticularized cheilostom; absence of glottoid apparatus; monoprodelphic reproductive system; vulva (V) = 81 to 84; spicules with trifurcated distal ends, simple gubernaculum, peloderan bursa with eight pairs of bursal papillae arranged in 1 + 1 + 1 + 2 + 1 + 2 arrangement. PMID:26941466

  11. Bumba, a replacement name for Maraca Pérez-Miles, 2005 and Bumbalennoni, a new tarantula species from western Amazonia (Araneae, Theraphosidae, Theraphosinae).

    PubMed

    Pérez-Miles, Fernando; Bonaldo, Alexandre Bragio; Miglio, Laura Tavares

    2014-01-01

    We propose the name Bumba as a new name for Maraca, preoccupied by Maraca Hebard, 1926 (Orthoptera). We describe and illustrate Bumbalennoni, a new theraphosid species from Caxiuanã, Pará, Brazil. This species differs from the other species of the genus in the extremely reduced keel on male palpal organ and in the higher number of labial and maxillary cuspules. Females additionally differ in the spermathecal morphology. As a consequence of the name replacement, three new combinations are established.

  12. Detailed morphological description of the mature larva of Globicornis corticalis (Eichhoff, 1863) (Dermestidae: Megatominae) with comparisons to related species.

    PubMed

    Kadej, Marcin; Jaroszewicz, Sylwia

    2013-01-01

    A description of the last larval instar (based on exuviae) of Globicornis corticalis (Eichhoff, 1863) (Coleoptera: Dermestidae) is presented. Morphological characters of Globicornis larvae are characterized and discussed, including antenna, epipharynx, mandible, maxilla, ligula with labial palpi, hastisetae, legs, tergites, and condition of the antecostal suture. Structural differences among mature larvae of G corticalis (Eichhoff, 1863), G emarginata (Gyllenhal, 1808) and G nigripes (Fabricius, 1792) are compared and summarized.

  13. Laser in dentistry: Biostimulation and surgery

    NASA Astrophysics Data System (ADS)

    Barzè, Franco; Palmieri, Beniamino; Scalise, Lorenzo; Rottigni, Valentina

    2012-09-01

    Laser therapy has achieved an important rule in cosmetic dentistry especially in the treatment of several complications such as leukoplakia, oral lichen planus, glossitis, oral mucositis, labial herpes virus, stomatitis, frenulum and oral hemangioma. In our study we enrolled 40 patients affected by these diseases to treat them with a new infrared dental laser demonstrating that it is extremely safe and effective in pain and postoperative discomforts reduction.

  14. Notes on species of the genus Chlaenius Bonelli, 1810 (Coleoptera: Carabidae, Chlaeniini) from four agro-climatic zones of Rajasthan, with description of two new species.

    PubMed

    Chanu, N Yaiphabi; Swaminathan, R

    2017-03-01

    Fourteen species of the genus Chlaenius from the semi-arid and sub-humid plain zones of Rajasthan (India) have been revised in this paper, including the description of two new species: Chlaenius (Lissauchenius) udaipurensis sp. nov. and Chlaenius (Chlaeniellus) pseudotristis sp. nov. A key to these species has been given with suitable line diagrams and photographs to illustrate key taxonomic characters including labrum, mentum, maxillary and labial palpi, pronotum, elytra and aedeagus.

  15. Acquired generalized anhidrosis: review of the literature and report of a case with lymphocytic hidradenitis and sialadenitis successfully treated with cyclosporine.

    PubMed

    Fujita, Kumi; Hatta, Kazuhiro

    2013-01-01

    We report a case of acquired generalized anhidrosis successfully treated with cyclosporine. A skin biopsy showed T cell infiltration around the sweat glands and labial biopsy revealed lymphoplasmacytic infiltration around the minor salivary gland, suggesting an underlying autoimmune disease such as Sjögren's syndrome. Administration of cyclosporine markedly improved the patient's condition and sympathetic skin response; thus cyclosporine may be effective for treating anhidrosis in patients with autoimmune disorders.

  16. The effect of finish line curvature on marginal fit of all-ceramic CAD/CAM crowns and metal-ceramic crowns.

    PubMed

    Tao, Jianxiang; Han, Dongwei

    2009-10-01

    To investigate the effect of abutment finish line curvature on the fit of all-ceramic CAD/CAM crowns and metal-ceramic crowns. Three types of finish line curvature abutments (1-, 3-, and 5-mm curvature) were prepared on typodont maxillary central incisors. For each type of abutment, 5 all-ceramic crowns (Cercon system, DeguDent) and 5 metal-ceramic crowns were fabricated. The marginal gaps of copings and veneered crowns were measured on a profile projector. The data were calculated and analyzed with 2-way ANOVA and Tukey HSD test (alpha = .05). The mean labial, lingual, mesial, and distal marginal gaps (SD) of all-ceramic crowns were similar: respectively, 54 (10), 51 (11), 47 (13), and 49 (9) microm for 1-mm curvature; 49 (12), 53 (11), 54 (10), and 55 (12) microm for 3-mm curvature; and 57 (12), 54 (11), 53 (10), and 52 (9) microm for 5-mm curvature. The mean labial, lingual, mesial, and distal marginal gaps (SD) of metal-ceramic crowns were 36 (7), 41 (9), 26 (8), and 28 (10) microm, respectively, for 1-mm curvature. The mean labial and lingual marginal gaps (SD) of metal-ceramic crowns for 3-mm curvature were 45 (8) and 48 (9) microm, respectively-significantly larger than mesial (P = .01 and .007) and distal (P = .03 and .02) gaps. The mean labial and lingual marginal gaps (SD) of metal-ceramic crowns for 5-mm curvature were 76 (10) and 74 (15) microm, respectively-significantly larger than mesial (P = .001 and .001) and distal (P = .001 and .001) gaps. The abutment finish line curvature had no significant effect on the marginal fit of all-ceramic crowns, but had a significant effect on the marginal fit of metal-ceramic crowns.

  17. Ashea megacephala Kim & Ahn (Coleoptera, Staphylinidae, Aleocharinae), a new gyrophaenine genus and species from Peru.

    PubMed

    Kim, Yoon-Ho; Ahn, Kee-Jeong

    2015-01-01

    Ashea megacephala, a new Peruvian genus and species is described. The specimens were collected on mushrooms and mushroom-associated trees. This genus can be readily distinguished from the other genera of the subtribe Gyrophaenina by the large head and the three indistinctly articulated labial palpomeres. A key to the known genera of Gyrophaenina is provided. A habitus photograph and illustrations of diagnostic characters are also presented.

  18. Complete removable dental prosthesis with the swing lock system: a clinical report.

    PubMed

    Aggarwal, Harshit; Cho, Seok-Hwan

    2014-11-01

    This clinical report describes the fabrication of a maxillary complete removable dental prosthesis with the swing lock system. The patient presented with large undercuts on the buccal and labial areas of the edentulous maxillary arch and a history of various failed alveoloplasty procedures that had attempted to remove the exostoses preventing denture insertion. The prosthodontic planning and treatment approach are discussed. Copyright © 2014 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  19. The Adaptive Significance of Enamel Loss in the Mandibular Incisors of Cercopithecine Primates (Mammalia: Cercopithecidae): A Finite Element Modelling Study

    PubMed Central

    Kupczik, Kornelius; Lev-Tov Chattah, Netta

    2014-01-01

    In several primate groups enamel is reduced or absent from the lingual (tongue) side of the mandibular incisor crowns akin to other placental and marsupial mammalian groups such as rodents, lagomorphs and wombats. Here we investigate the presumed adaptation of crowns with unilateral enamel to the incision of tough foods in cercopithecines, an Old World monkey subfamily, using a simulation approach. We developed and validated a finite element model of the lower central incisor of the rhesus macaque (Macaca mulatta) with labial enamel only to compute three-dimensional displacements and maximum principal stresses on the crown subjected to compressive loads varying in orientation. Moreover, we developed a model of a macaque incisor with enamel present on both labial and lingual aspects, thus resembling the ancestral condition found in the sister taxon, the leaf-eating colobines. The results showed that, concomitant with experimental results, the cercopithecine crown with unilateral enamel bends predominantly towards the inside of the mouth, while displacements decreased when both labial and lingual enamel are present. Importantly, the cercopithecine incisor crown experienced lower maximum principal stress on the lingual side compared to the incisor with enamel on the lingual and labial aspects under non-axial loads directed either towards the inside or outside of the mouth. These findings suggest that cercopithecine mandibular incisors are adapted to a wide range of ingestive behaviours compared to colobines. We conclude that the evolutionary loss of lingual enamel in cercopithecines has conferred a safeguard against crown failure under a loading regime assumed for the ingestion (peeling, scraping) of tough-skinned fruits. PMID:24831704

  20. The adaptive significance of enamel loss in the mandibular incisors of cercopithecine primates (Mammalia: Cercopithecidae): a finite element modelling study.

    PubMed

    Kupczik, Kornelius; Lev-Tov Chattah, Netta

    2014-01-01

    In several primate groups enamel is reduced or absent from the lingual (tongue) side of the mandibular incisor crowns akin to other placental and marsupial mammalian groups such as rodents, lagomorphs and wombats. Here we investigate the presumed adaptation of crowns with unilateral enamel to the incision of tough foods in cercopithecines, an Old World monkey subfamily, using a simulation approach. We developed and validated a finite element model of the lower central incisor of the rhesus macaque (Macaca mulatta) with labial enamel only to compute three-dimensional displacements and maximum principal stresses on the crown subjected to compressive loads varying in orientation. Moreover, we developed a model of a macaque incisor with enamel present on both labial and lingual aspects, thus resembling the ancestral condition found in the sister taxon, the leaf-eating colobines. The results showed that, concomitant with experimental results, the cercopithecine crown with unilateral enamel bends predominantly towards the inside of the mouth, while displacements decreased when both labial and lingual enamel are present. Importantly, the cercopithecine incisor crown experienced lower maximum principal stress on the lingual side compared to the incisor with enamel on the lingual and labial aspects under non-axial loads directed either towards the inside or outside of the mouth. These findings suggest that cercopithecine mandibular incisors are adapted to a wide range of ingestive behaviours compared to colobines. We conclude that the evolutionary loss of lingual enamel in cercopithecines has conferred a safeguard against crown failure under a loading regime assumed for the ingestion (peeling, scraping) of tough-skinned fruits.

  1. Comparison of the initial orthodontic force systems produced by a new lingual bracket system and a straight-wire appliance.

    PubMed

    Fuck, Lars-Michael; Wiechmann, Dirk; Drescher, Dieter

    2005-09-01

    Over the last few years, lingual appliances have become an established orthodontic treatment technique. Many studies have concentrated on various esthetic aspects, on laboratory and clinical procedures, and on patient comfort and compliance. The orthodontic force systems of these appliances, however, have not yet been investigated. The aim of this study was thus to determine the forces and moments produced by a new lingual bracket system during the leveling phase of orthodontic treatment and to compare those with the corresponding force system of a labial straight-wire appliance. The intra-oral situation of ten patients undergoing orthodontic treatment was replicated in measurement casts fitted with lingual and labial brackets. Special care was taken to precisely reproduce each patient's interbracket geometry. We measured each tooth's force systems as generated by a leveling arch inserted into the lingual and labial brackets. The resulting force systems of both appliances were found to be quite similar with regard to the magnitude of most force and moment components. Only the first molars were subjected to considerably greater single forces with the lingual appliance. Tipping moments were found to be significantly smaller with the lingual technique, whereas the rotational moments were significantly smaller with the labial appliance. All in all we noted significant differences between the two techniques only in certain areas which upon closer examination were distributed over only a few tooth types. The initial force systems produced by the new lingual bracket system proved to be comparable with those delivered by a conventional straight-wire appliance. The actual levels of forces and moments, however, were found in certain cases to be too heavy with both techniques. We therefore recommend the development of leveling wires producing considerably lighter forces and moments.

  2. Cadaveric Assessment of Lip Injections: Locating the Serious Threats.

    PubMed

    Tansatit, Tanvaa; Apinuntrum, Prawit; Phetudom, Thavorn

    2017-04-01

    Lip augmentation could be a possible cause of blindness following filler injections. This study evaluated the risk by simulating clinical scenarios of marginal injections to the upper and lower lips and then evaluated the risk of vascular injuries. A 22G cannula was inserted bilaterally along the wet-dry junction of the upper and lower lip margins in fifteen cadavers, and then both lips were dissected to verify possible injuries to the superior and inferior labial arteries. The position of the labial arteries in the vermilion zone was documented to determine the appropriate injection technique. In the marginal injections to the lips, arterial injuries occurred at the medial segment of the vermilion zone of both the upper and lower lips, at the terminal part of the labial arteries or a distal branch. Considering arterial anatomy, the upper lip has a higher chance of arterial injury than the lower lip. The cannula should not be inserted in the submucosa as it is recommended to evert the vermilion because both the superior and inferior labial arteries are located in the submucosa of the medial and middle segments of the vermilion in all specimens. Awareness of the possibility of vascular injury is necessary during injections of the medial segments of the vermilion of the lips. Vermilion border and marginal injections are recommended for safe and effective lip augmentation. Deep injection around the oral commissure and submucosal injection of the medial and middle segments of the vermilion zone are prohibited because of the high risk of arterial injury. This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to

  3. Unusual ectopic eruption of a permanent central incisor following an intrusion injury to the primary tooth.

    PubMed

    Canoglu, Ebru; Akcan, Cenk Ahmet; Baharoglu, Erdinç; Gungor, H Cem; Cehreli, Zafer C

    2008-10-01

    Intrusive luxation of primary teeth carries a high risk of damage to underlying permanent tooth germs. Ectopic eruption of permanent incisors is an unusual outcome of traumatic injury to their predecessors. In this case report, we describe the multidisciplinary management of the consequences of a primary tooth intrusion that led to severe ectopic eruption of the permanent left central incisor in a horizontal position at the level of the labial sulcus.

  4. Floral double mesiodentes: A rare case report

    PubMed Central

    Singaraju, Gowri Sankar; Reddy, B. Rama Mohan; Supraja, G.; Reddy, K. Narayana

    2015-01-01

    Mesiodens is the most commonly erupting supernumerary in the midline between two maxillary central incisors. Mesiodentes is a rare condition when mesiodens erupt in multiples, which may present as either labial or palatal to permanent central incisors. We report a rare case of double mesiodentes (non-syndromic mesiodentes) with floret like appearance. The presence of mesiodens has functional and esthetic implications. Careful radiographic evaluation should be done to prevent complications during their extraction. PMID:25810670

  5. Floral double mesiodentes: A rare case report.

    PubMed

    Singaraju, Gowri Sankar; Reddy, B Rama Mohan; Supraja, G; Reddy, K Narayana

    2015-01-01

    Mesiodens is the most commonly erupting supernumerary in the midline between two maxillary central incisors. Mesiodentes is a rare condition when mesiodens erupt in multiples, which may present as either labial or palatal to permanent central incisors. We report a rare case of double mesiodentes (non-syndromic mesiodentes) with floret like appearance. The presence of mesiodens has functional and esthetic implications. Careful radiographic evaluation should be done to prevent complications during their extraction.

  6. Maxillary frenectomy using a carbon dioxide laser in a pediatric patient: a case report.

    PubMed

    Shetty, Kishore; Trajtenberg, Cynthia; Patel, Chandni; Streckfus, Charles

    2008-01-01

    Dental lasers contribute significantly to the field of cosmetic dentistry, providing an invaluable resource for clinicians who perform different types of esthetic procedures. An increasing number of general dentists are using the carbon dioxide (CO2) laser for surgical procedures. However, the literature about using a CO2 laser to perform oral soft tissue ablation in the pediatric patient is limited. This case report presents a successful case of a maxillary labial frenectomy in a pediatric patient using a CO2 laser.

  7. Gingival pigmentation index proposal of a new index with a brief review of current indices

    PubMed Central

    Peeran, Syed Wali; Ramalingam, Karthikeyan; Peeran, Syed Ali; Altaher, Omar Basheer; Alsaid, Fatma Mojtaba; Mugrabi, Marei Hamed

    2014-01-01

    Cosmetic expectations have increased with time and current trends speak volumes about gingival esthetics and smile designing. Gingival pigmentation especially on the labial aspect of anterior teeth has become an important component of general esthetics. Various physiologic and pathologic factors cause gingival pigmentation. The existing indices do not deal with the etiology, extent and severity of gingival pigmentation. Hence, we propose a new classification and index for gingival pigmentation to assess the treatment needs for the patient. PMID:24966785

  8. Herpes simplex virus infection during pregnancy.

    PubMed

    Stephenson-Famy, Alyssa; Gardella, Carolyn

    2014-12-01

    Genital herpes in pregnancy continues to cause significant maternal morbidity, with an increasing number of infections being due to oral-labial transmission of herpes simplex virus (HSV)-1. Near delivery, primary infections with HSV-1 or HSV-2 carry the highest risk of neonatal herpes infection, which is a rare but potentially devastating disease for otherwise healthy newborns. Prevention efforts have been limited by lack of an effective intervention for preventing primary infections and the unclear role of routine serologic testing.

  9. VOT in the babbling of French- and English-learning infants

    PubMed Central

    Whalen, D. H.; Levitt, Andrea G.; Goldstein, Louis M.

    2009-01-01

    Different languages use voice onset time (VOT) in different ways to signal the voicing contrast, for example, short lag/long lag (English) vs. prevoiced/short lag (French). Also, VOT depends on place of articulation, with labial VOTs being shorter than velar and alveolar and, sometimes, alveolar being shorter than velar. Here we examine the VOT in babbled utterances of five French-learning and five English-learning infants at ages 9 and 12 months. There was little or no difference between the languages for duration of positive VOTs, which were usually in the “short lag” range. The duration of prevoicing also did not differ between languages, but the proportion of prevoiced utterances did (French-learning infants: 44.2% prevoicing; English-learning: 14.3%). Labial, alveolar and velar stops differed in VOT, with alveolar longer than labial and velar longer than alveolar, suggesting a mechanical cause. The lack of long-lag VOT indicates that the English-learning infants have not mastered aspiration by 12 months. The different proportions of prevoicing, however, suggest that the French-learning infants attempt to imitate the prevoicing that is used frequently (and contrastively) in their native language environment. The results suggest that infants are sensitive to the voicing categories of the ambient language but that they may be able to control prevoicing more successfully than aspiration. PMID:19641636

  10. Angular measurement for determining muscle tonus in facial paralysis.

    PubMed

    Tessitore, Adriana; Magna, Luis Alberto; Paschoal, Jorge Rizzato

    2010-01-01

    the decrease of facial movements in peripheral facial paralysis and the resulting aesthetical sequels may have important emotional repercussions as a consequence to the functional deficit, and depending on the intensity of the clinical condition. Orofacial rehabilitation has as a purpose to favor the recovery of orofacial movements and to adequate and/or adapt orofacial functions and facial mimic. However, quantifying therapeutic results in an attempt to measure the muscle tonus is a challenge. Generally, the used forms of measurement are general and subjective. to propose the labial commissure angle as an anthropometric marker and to evaluate its reliability as an objective tool to evaluate the modification of the facial muscle tonus after rehabilitation. participants of the study were 20 patients presenting peripheral facial paralysis - level IV. The study was conducted using images from the photographical documentation taken fifteen days to one year post-onset of facial paralysis. The angle was measured by tracings determined by pre-established anthropometric facial points, such as the line between the glabella and the gnation and the crossing with the left and right chelion points determining an angle manually measured with a protractor on the photography. The average Labial Commissure Angle before treatment was of 101.70 and after rehabilitation of 93.80 (standard deviation, SD = 4.3). The statistical analysis indicated a significant difference (p < 0.001). the results obtained suggest that the Labial Commissure Angle allows the objective evaluation of facial muscle tonus modification.

  11. Soft tissue facial morphometry before and after total oral rehabilitation with implant-supported prostheses.

    PubMed

    Tartaglia, Gianluca M; Dolci, Claudia; Sidequersky, Fernanda V; Ferrario, Virgilio F; Sforza, Chiarella

    2012-11-01

    The objective of the current study was to assess a low-cost, noninvasive facial morphometric digitizer to assist the practitioner in three-dimensional soft-tissue changes before and after oral rehabilitation. Twenty-two patients aged 45 to 82 years, all with edentulous maxilla and mandible, were assessed both before and after receiving their definitive complete implant-supported prostheses (each received 4-11 implants in each dental arch; full-arch fixed prostheses were made). The three-dimensional coordinates of 50 soft-tissue facial landmarks were collected with a noninvasive digitizer; labial and facial areas, volumes, angles, and distances were compared without and with the prostheses. Dental prostheses induced significant reductions in the nasolabial, mentolabial, and interlabial angles, with increased labial prominence (P < 0.05, Wilcoxon test). Lip vermilion area and volume significantly increased; significant increments were found in the vertical and anteroposterior labial dimensions. The presence of the dental prostheses significantly (P < 0.001) modified the three-dimensional positions of several soft-tissue facial landmarks. In conclusion, the current approach enabled quantitative evaluation of the final soft-tissue results of oral rehabilitation with implant-supported prostheses, without submitting the patients to invasive procedures. The method could assess the three-dimensional appearance of the facial soft tissues of the patient while planning the provisional prosthetic restoration, providing quantitative information to prepare the best definitive prosthesis.

  12. Health status of tadpoles and metamorphs of Rhinella arenarum (Anura, Bufonidae) that inhabit agroecosystems and its implications for land use.

    PubMed

    Babini, María Selene; Bionda, Clarisa de Lourdes; Salas, Nancy Edith; Martino, Adolfo Ludovico

    2015-08-01

    Perturbations of water bodies near agricultural and livestock systems can affect embryonic and larval stages of anurans and negatively impact adult populations and structure of amphibian communities. This study is focused on early development of Rhinella arenarum, for which body growth, abnormalities in the oral disc and genetic damage on erythrocytes were analyzed to establish the impact of agroecosystems on local populations of amphibians. Tadpoles and metamorphs of R. arenarum were collected in three agroecosystems (namely, C1, C2, and C3) and in a site without agricultural and livestock activities (SM) from central Argentina. Egg masses of C1 were extracted for breeding tadpoles under laboratory conditions (Lab). Tadpoles were in small size and lighter in weight in C1 and C2. Metamorphs were shorter and lighter in weight in C1 and C3. In SM and Lab samples, no tadpoles with abnormal LTRF (labial tooth row formula) or without labial teeth were observed. In C1, the highest frequency of abnormal LTRF was recorded and was the only site in which tadpoles without labial teeth were found. In C1 and C2 the tadpoles had highest micronucleus frequencies and nuclear abnormalities. C1 can be considered as the site with the highest anthropogenic perturbation and with less healthy tadpoles. Livestock practices such as alternating cattle between parcel and keeping a buffer between crops and water bodies, would allow a better development of the first aquatic stages that are essential for the conservation of the anuran populations.

  13. The effects of alveolar bone loss and miniscrew position on initial tooth displacement during intrusion of the maxillary anterior teeth: Finite element analysis

    PubMed Central

    Cho, Sun-Mi; Choi, Sung-Hwan; Sung, Sang-Jin; Yu, Hyung-Seog

    2016-01-01

    Objective The aim of this study was to determine the optimal loading conditions for pure intrusion of the six maxillary anterior teeth with miniscrews according to alveolar bone loss. Methods A three-dimensional finite element model was created for a segment of the six anterior teeth, and the positions of the miniscrews and hooks were varied after setting the alveolar bone loss to 0, 2, or 4 mm. Under 100 g of intrusive force, initial displacement of the individual teeth in three directions and the degree of labial tilting were measured. Results The degree of labial tilting increased with reduced alveolar bone height under the same load. When a miniscrew was inserted between the two central incisors, the amounts of medial-lateral and anterior-posterior displacement of the central incisor were significantly greater than in the other conditions. When the miniscrews were inserted distally to the canines and an intrusion force was applied distal to the lateral incisors, the degree of labial tilting and the amounts of displacement of the six anterior teeth were the lowest, and the maximum von Mises stress was distributed evenly across all the teeth, regardless of the bone loss. Conclusions Initial tooth displacement similar to pure intrusion of the six maxillary anterior teeth was induced when miniscrews were inserted distal to the maxillary canines and an intrusion force was applied distal to the lateral incisors. In this condition, the maximum von Mises stresses were relatively evenly distributed across all the teeth, regardless of the bone loss. PMID:27668194

  14. Requirement of integrin β3 for iron transportation during enamel formation.

    PubMed

    Yoshida, T; Kumashiro, Y; Iwata, T; Ishihara, J; Umemoto, T; Shiratsuchi, Y; Kawashima, N; Sugiyama, T; Yamato, M; Okano, T

    2012-12-01

    Rodent incisors exhibit pigmentation on their labial surfaces. Although previous studies have shown that this pigment is composed of iron, the existence of other elements has not been investigated. This study found that the lower incisors of CD61, also known as integrin β3, null mice (CD61(-/-)) lacked pigmentation. Although ameloblasts differentiated and formed enamel normally, no ferric ion accumulation was observed in maturation-stage ameloblasts in CD61(-/-) mice. Surface elements of control and CD61-/- lower incisors were compared by x-ray photoelectron spectroscopy (XPS). XPS analysis detected C, Ca, N, O, and P on the labial surfaces of lower incisors of both mice, whereas Fe was detected only in control samples. No peak of non-ferrous metal or other element was detected in either group. Quantitative RT-PCR analysis of 18 iron-transportation-related genes with mRNA from maturation-stage ameloblasts and ALC, a pre-ameloblastic cell line, was performed. The results suggested that CD61 regulates the expressions of Slc11a2 and Slc40a1, both of which are involved in iron transportation in epithelial tissues. These results suggested that the pigment on the labial surface of mouse incisors is composed of Fe and that both anemia and reduction of iron-transporting proteins may cause the loss of pigmentation in CD61(-/-) mice.

  15. Class III Restoration of Anterior Primary Teeth: In Vitro Retention Comparison of Conventional, Modified and Air-abrasion Treated Preparations.

    PubMed

    Asl Aminabadi, Naser; Najafpour, Ebrahim; Erfanparast, Leila; Samiei, Mohammad; Haghifar, Monireh; Sighari Deljavan, Alireza; Jamali, Zahra; Pournaghi Azar, Fatemeh; Shokravi, Marzieh

    2014-01-01

    Background and aims. Anterior esthetic restoration is challenging in pediatric dentistry, due to limited durability and poor retention of the restoration.This study assessed the effect of air abrasion on tensile failure load of composite class III restorations using different preparation techniques. Materials and methods. 100 extracted human anterior primary teeth were divided, based on the preparation methods, into four groups each consisting of 25 subjects : conventional (A), labial surface bevel (B), conventional + air abrasion (C), and labial surface bevel + air abrasion (D). After restoring cavities, tensile failure load of samples was measured in Newton by Universal testing machine at a crosshead speed of 1 mm per minute. The data were analyzed by Kruskal-Wallis and Mann Whitney U tests using SPSS software. Results. There were statistically significant differences between groups A and C (P = 0.003), groups A and B (P & 0.001), groups A and D (P & 0.001), groups B and C (P = 0.028), groups B and D (P = 0.027), and also groups C and D (P& 0.001). Group D demonstrated the highest mean tensile failure load. Conclusion. Labial surface bevel treated by air abrasion showed significantly more retention of composite restoration.

  16. Enfleurage, lipid recycling and the origin of perfume collection in orchid bees

    PubMed Central

    Eltz, Thomas; Zimmermann, Yvonne; Haftmann, Jenny; Twele, Robert; Francke, Wittko; Quezada-Euan, J. Javier G; Lunau, Klaus

    2007-01-01

    Enfleurage, the extraction of elusive floral scents with the help of a lipophilic carrier (grease), is widely used in the perfume industry. Male neotropical orchid bees (Euglossini), which accumulate exogenous fragrances as pheromone analogues, use a similar technique. To collect fragrances, the bees apply large amounts of straight-chain lipids to odoriferous surfaces from their cephalic labial glands, which dissolve the volatiles, and the mixture is then transferred to voluminous hind-leg pockets. Here, we show that males do in fact operate a lipid conveyor belt to accumulate and concentrate their perfume. From the hind-leg pockets of caged male Euglossa viridissima, deuterated derivatives of carrier lipids were consecutively sequestered, shuttled back to the labial glands and reused on consecutive bouts of fragrance collection. Such lipid cycling is instrumental in creating complex perfume bouquets. Furthermore, we found that labial glands of male orchid bees are strikingly similar to those of scent-marking male bumblebees in terms of size, form and structure. This, and a prominent overlap in secretory products, led us to propose that perfume collection evolved from scent-marking in ancestral corbiculate bees. PMID:17848369

  17. The effects of alveolar bone loss and miniscrew position on initial tooth displacement during intrusion of the maxillary anterior teeth: Finite element analysis.

    PubMed

    Cho, Sun-Mi; Choi, Sung-Hwan; Sung, Sang-Jin; Yu, Hyung-Seog; Hwang, Chung-Ju

    2016-09-01

    The aim of this study was to determine the optimal loading conditions for pure intrusion of the six maxillary anterior teeth with miniscrews according to alveolar bone loss. A three-dimensional finite element model was created for a segment of the six anterior teeth, and the positions of the miniscrews and hooks were varied after setting the alveolar bone loss to 0, 2, or 4 mm. Under 100 g of intrusive force, initial displacement of the individual teeth in three directions and the degree of labial tilting were measured. The degree of labial tilting increased with reduced alveolar bone height under the same load. When a miniscrew was inserted between the two central incisors, the amounts of medial-lateral and anterior-posterior displacement of the central incisor were significantly greater than in the other conditions. When the miniscrews were inserted distally to the canines and an intrusion force was applied distal to the lateral incisors, the degree of labial tilting and the amounts of displacement of the six anterior teeth were the lowest, and the maximum von Mises stress was distributed evenly across all the teeth, regardless of the bone loss. Initial tooth displacement similar to pure intrusion of the six maxillary anterior teeth was induced when miniscrews were inserted distal to the maxillary canines and an intrusion force was applied distal to the lateral incisors. In this condition, the maximum von Mises stresses were relatively evenly distributed across all the teeth, regardless of the bone loss.

  18. The effect of incomplete crown ferrules on fracture resistance and failure modes of endodontically treated maxillary incisors restored with quartz fiber post, composite core, and crowns

    PubMed Central

    Muangamphan, Panorjit; Sattapan, Boonrat; Kukiattrakoon, Boonlert; Thammasitboon, Kewalin

    2015-01-01

    Aim: To investigate the fracture resistance of restored endodontically treated teeth (RETT) with fiber posts, cores, and crowns with limited ferrules. Materials and Methods: Sixty maxillary anterior teeth were endodontically treated and decoronated 2 mm above the cemento-enamel junction, and then divided into 6 groups of 10 teeth each; Group circumferential ferrule (2FR), Group ferrule in the labial, mesial, and palatal region (2FR-LaMPa), Group ferrule in the labial, and palatal region (2FR-LaPa), Group 2FR-Pa and 2FR-La respectively, and Group 0FR (no ferrule). All 60 prepared teeth were then restored with quartz fiber posts, resin composite cores, and metal crowns. The specimens were subjected to load until failure occurred. Data were analyzed using one-way analysis of variance and Tukey's tests (α = 0.05). The mode of failure was determined under a stereoscope. Results: A statistical significant difference was found among groups 2FR-LaMPa, 2FR-Pa, 2FR-LaPa, and 2FR from the group 2FR-La, and from the group 0FR (P < 0.01). The predominant mode of failure was an oblique palatal to labial root fracture for the groups with remaining ferrules. Conclusion: For RETT that have incomplete crown ferrules, the location of the ferrules may affect their fracture resistance. PMID:26069401

  19. Simulated bone remodeling around tilted dental implants in the anterior maxilla.

    PubMed

    Wang, Chao; Zhang, Weiping; Ajmera, Deepal Haresh; Zhang, Yun; Fan, Yubo; Ji, Ping

    2016-06-01

    Dental implants have to be placed with the long axis in different angulations due to the change in bone morphology. The objective of this study was to investigate the different bone remodeling response induced by the tilted dental implants and to assess whether it could lead to bone loss and implant failure. In this study, bone remodeling due to palato-labially inclined dental implants placed in the anterior maxillary incisor region was simulated. CT-based finite element models of a maxillary bone with dental implants were created herein. Five dental implants were placed at [Formula: see text], [Formula: see text], [Formula: see text], [Formula: see text] and [Formula: see text], respectively. The remodeling progression was recorded and compared. Model [Formula: see text] (palatal side) shows the highest bone density values, but the inclined implant at [Formula: see text] (labial side) leads to significant bone loss. From a biomechanical perspective, it is speculated that a palatally inclined implant is more likely to enhance the bone density in the maxillary anterior region, but labial inclination of implant could jeopardize its stability.

  20. Collagenase in Sjögren's syndrome.

    PubMed Central

    Konttinen, Y T; Kangaspunta, P; Lindy, O; Takagi, M; Sorsa, T; Segerberg, M; Tschesche, H; Eisen, A Z

    1994-01-01

    OBJECTIVE--To study collagenase production in labial salivary glands in patients with Sjögren's syndrome (SS). METHODS--Collagenases were localised in labial salivary glands by immunohistochemistry. Collagenase activity against triple helical type I collagen monomers in stimulated saliva was measured using sodium dodecyl sulphate polyacrylamide gel electrophoresis and laser densitometry; tissue inhibitor metalloproteinase (TIMP) was measured by enzyme linked immunosorbent assay. RESULTS--Cells containing collagenase of matrix metalloproteinase (MMP)-1 type were more frequent and more intensely staining in SS than in healthy glands. Only SS saliva contained functional enzyme (11.7 (6.8) x 10(-6) IU/1). Cells containing MMP-8 type neutrophil collagenase were not found in situ, which was in accordance with sialochemical findings/doxycycline inhibition studies. TIMP was found in both SS and normal saliva. CONCLUSIONS--Fibroblast, but not neutrophil type, collagenase is synthesised, secreted, and subsequently activated, but is not inhibited by TIMP in labial salivary glands or saliva in SS. Collagenase may destroy glandular and salivary duct tissue and perturb factors influencing the morphogenetic extracellular matrix. Images PMID:7864694

  1. Soft tissue changes after a mandibular osteotomy for symmetric skeletal class III malocclusion.

    PubMed

    Ohba, Seigo; Kohara, Haruka; Koga, Takamitsu; Kawasaki, Takako; Miura, Kei-Ichirou; Yoshida, Noriaki; Asahina, Izumi

    2016-10-31

    The soft tissue profile is crucial to esthetics after orthognathic surgery. The aim of this study was to assess the soft tissue changes of the subnasal and submental regions more than 1 year after a sagittal split ramus osteotomy (SSRO) in patients with skeletal class III malocclusion. A total of 22 patients with mandibular prognathism were included in this study. Patients had lateral cephalograms before and more than 1 year after they underwent an isolated SSRO. Soft and hard tissue changes were assessed using the lateral cephalograms. The lower lip, labiomenton, and soft tissue menton moved posteriorly by 85, 89, and 88% compared with the corresponding hard tissue, and the movement of the soft tissue B point and the top of the chin nearly reflected the displacement of the hard tissues, at 96 and 99%, respectively. The labiomenton, stomions, and naso-labial angles were changed after the mandibular set-back and the changes in these angles correlated with either the width of the soft tissue or skeletal displacement. The naso-labial angle could be altered even if an isolated mandibular osteotomy is performed. Changes to the stomions and naso-labial angles were affected by hard tissue movement, while changes to the labiomental angle were affected by the width of the soft tissue after the mandibular osteotomy. It is important to create an accurate preoperative prediction of the esthetic outcomes after a mandibular osteotomy by considering the interrelations between the hard and soft tissues.

  2. Two new species of Cylicospirura Vevers, 1922 (Nematoda: Spirocercidae) from carnivores in southern Africa, with validation of the related genera Gastronodus Singh, 1934 and Skrjabinocercina Matschulsky, 1952.

    PubMed

    Junker, Kerstin; Lane, Emily P; McRee, Anna E; Foggin, Chris; van Dyk, D Schalk; Mutafchiev, Yasen

    2013-09-01

    Two new species of Cylicospirura Vevers, 1922 are described from carnivores from southern Africa. Cylicospirura crocutae Junker et Mutafchiev sp. n. from Crocuta crocuta (Erxleben) in Zimbabwe is distinguished from its congeners by combinations of characters, including the presence of four cephalic and four external labial papillae, while internal labial papillae were not distinct, the presence of groups of small accessory teeth between the six large tricuspid teeth, the fifth and the sixth pairs of the caudal papillae being equidistant from the cloaca, and a large ratio of length of the muscular oesophagus to that of the glandular oesophagus. Cylicospirura pardalis Junker et Mutafchiev sp. n. from Panthera pardus (Linnaeus) in the Republic of South Africa is characterized by having tricuspid teeth with large, claw-like, abaxial cusps, four cephalic and six internal labial papillae. Based on the number of caudal papillae and the position of the vulva, the subgenera Gastronodus Singh, 1934 and Skrjabinocercina Matschulsky, 1952 are re-elevated to generic rank. Amended diagnoses are proposed for the genera Cylicospirura, Gastronodus and Skrjabinocercina. Petrowospirura lyncis Matschulsky, 1952 is recognized as valid and, together with P. petrowi Sadykhov, 1957 and P. barusi Arya, 1979, is transferred to Cylicospirura as C. lyncis (Matschulsky, 1952) Junker et Mutafchiev comb. n., C. petrowi (Sadykhov, 1957) Junker et Mutafchiev comb. n. and C. barusi (Arya, 1979) Junker et Mutafchiev comb. n., respectively.

  3. Relationship of Incisive Papilla to Maxillary Incisors and Canines.

    PubMed

    Shrestha, Suraksha; Joshi, Sarita Pradhan; Yadav, Santosh Kumar

    2016-04-01

    The study was carried to find a relationship between the postextraction stable landmark, the incisive papilla, and the most labial position of the maxillary central incisor teeth, which occurred in Nepalese population. Casts of the subjects selected by nonprobability random sampling meeting the inclusion criteria were obtained. Each casts were standardized with respect to the occlusal plane and a photographic technique was used to measure the distance from the tangent of the labial surface of the central incisors to the posterior border of the incisive papilla. The measurements were made using Adobe Photoshop and results were analyzed by using appropriate statistical methods. Most appropriate software (SPSS) for the purpose was used to generate all desired values. The data obtained suggested that the distance from the labial surface of maxillary central incisors to the posterior border of the incisive papilla ranged from 9 to 15.9 mm with a mean of 11.59 mm (SD 1.3). Various other results were also found after evaluation of the arch forms in relation to sex and race. Within the limitations of the study, these results suggested that there is a relationship between the maxillary central incisors and the incisive papilla aiding in the anteroposterior positioning of the anterior tooth. The clinical relevance of the study lies in application of the incisive papilla as a starting point in the preliminary location of maxillary incisors and canines during construction of the denture in absence of preextraction records.

  4. A new species of Coryogalops (Perciformes: Gobiidae) and the first adult record of Feia nympha from the Red Sea.

    PubMed

    Kovačić, Marcelo; Bogorodsky, Sergey V; Mal, Ahmad O

    2016-03-31

    A new species of the gobiid genus Coryogalops, C. nanus sp. nov. is described from the Red Sea. Coryogalops nanus sp. nov. is distinguished from congeners in having dorsal-fin rays VI + I,10; anal-fin rays I,9; pectoral-fin rays 12-14 (lowest count known for the genus), two upper rays with free tips; pelvic fins I,5, joined to form an emarginate disc, no pelvic frenum; predorsal area and narrow area at base of first dorsal fin naked; longitudinal scale series 26-29; transverse scale rows counted forward 6-7; transverse scale rows counted backward 7-8; circumpeduncular scale rows 11-12; seven transverse suborbital rows of sensory papillae; no tentacle above upper eye margin; anterior nostril tubular, without flap at its tip, posterior nostril pore-like; body semitranslucent, covered with small scattered orange-yellow spots and speckles, those in predorsal area contain black dots; an internal row of white spots along ventral part of body above anal-fin base and on caudal peduncle; head with small scattered orange to yellowish brown spots; first dorsal fin with two broad white bands at base of fin and distally, and with hyaline area densely dotted with melanophores in the middle of fin; preserved specimens opaque white to yellowish with sparse melanophores. An adult specimen of Feia nympha is recorded for the first time in the Red Sea and the lateral line system of this species is described.

  5. The effect of laterally positioned flap-revised technique and 24% ethylenediaminetetraacetic acid root conditioning on root coverage: A case report

    PubMed Central

    Singh, Jagmohan; Bharti, Vipin

    2014-01-01

    Complete root coverage is considered the true goal of treatment of gingival recession defects because only complete coverage assures recovery from the hypersensitivity and esthetic defects associated with recession areas. Previous studies have shown that the laterally positioned flap (LPF) technique or root surface biomodification yields a higher percentage of complete root coverage upon gingival recession treatment. This article highlights the use of the laterally positioned pedicle flap-revised technique (LPFRT) as a modification of the LPF technique, along with 24% EDTA gel as a root surface biomodification agent, in the management of localized gingival recession defects. Clinical examination revealed a Miller class II recession defect on the buccal aspect of the lower right central incisor, as well as the presence of aberrant frenum pull adjacent to the recession defect. The LPFRT, together with 24% EDTA gel, was speculated to cover the gingival recession defect. The frenectomy, along with periosteal fenestration, was planned simultaneously with LPFRT. After 6 months of therapy, the clinical condition was stable with complete root coverage and satisfactory healing of the gingival tissues at both the donor and recipient sites with no signs of inflammation. PMID:25057234

  6. Management of an Adult with Spaced Dentition, Class III Malocclusion and Open-bite Tendency

    PubMed Central

    Kaya, Demet; Taner, Tulin Ugur

    2011-01-01

    The aim of this case report was to present the orthodontic treatment of an adult with spaced dentition, Class III malocclusion, and open-bite tendency. A 28.4-year-old adult woman was concerned about the unesthetic appearance of her spaced dentition localized at both upper and lower arches while smiling. She had a mild tongue thrust, hypertropic upper frenum, and mild speech difficulty while pronouncing “s”. Her profile was straight with prominent lips. Molar relationship was Class III on both sides. Anterior teeth were in an end-to-end relationship. Lower dental midline was deviated to the left side. Cephalometric analysis revealed a skeletal Class III relationship with hyperdivergent facial pattern. The treatment plan included myotherapeutic exercises for the tongue thrust habit and a diagnostic set-up for closure of diastemas. A strict retention protocol was followed combined with gingivoplasty, fiberotomy, and frenectomy procedures. All spaces were closed successfully, adequate overbite and overjet relationships were obtained, and tongue thrust habit and speech difficulty while pronouncing “s” were eliminated. Clinical and cephalometric results indicated the maintenance of the treatment outcome at 6-months post-retention period. PMID:21228963

  7. The Versatility of 980 nm Diode Laser in Dentistry: A Case Series

    PubMed Central

    Derikvand, Nahid; Chinipardaz, Zahra; Ghasemi, Sara; Chiniforush, Nasim

    2016-01-01

    Introduction: Laser surgery has been considered a popular alternative over conventional modalities in dentistry during the last few years. Among different types of lasers, diode lasers have gained special attention in oral soft tissue surgery. Case Reports: Five patients were referred to a private office. After careful evaluation of medical history and oral examination, oral diagnosis and treatment plan of each patient was established as follows: (1) A 21-year-old female with ankyloglossia (tongue-tie); (2) A 65-year-old female with a poor denture fit needing vestibuloplasty and frenectomy; (3) A 10-year-old male patient with pigmented gingiva in mandible and maxilla; (4) A 14-year-old female needing exposure of maxillary right canine for bracket bonding; and (5) A 25-year-old female patient who has a gingival maxillary frenum with a nodule. The treatment plan for all the patients was laser surgery with diode laser at 980 nm, in continuous mode. Results: All the patients experienced normal healing process with no postoperative complications. Favorable outcomes of laser surgery were observed on follow-up sessions. Conclusion: Considering the versatility of the 980 nm diode laser in oral soft tissue surgeries and the advantages of laser surgery, this study suggests the use of 980 nm diode laser in this regard. PMID:28144444

  8. The Versatility of 980 nm Diode Laser in Dentistry: A Case Series.

    PubMed

    Derikvand, Nahid; Chinipardaz, Zahra; Ghasemi, Sara; Chiniforush, Nasim

    2016-01-01

    Introduction: Laser surgery has been considered a popular alternative over conventional modalities in dentistry during the last few years. Among different types of lasers, diode lasers have gained special attention in oral soft tissue surgery. Case Reports: Five patients were referred to a private office. After careful evaluation of medical history and oral examination, oral diagnosis and treatment plan of each patient was established as follows: (1) A 21-year-old female with ankyloglossia (tongue-tie); (2) A 65-year-old female with a poor denture fit needing vestibuloplasty and frenectomy; (3) A 10-year-old male patient with pigmented gingiva in mandible and maxilla; (4) A 14-year-old female needing exposure of maxillary right canine for bracket bonding; and (5) A 25-year-old female patient who has a gingival maxillary frenum with a nodule. The treatment plan for all the patients was laser surgery with diode laser at 980 nm, in continuous mode. Results: All the patients experienced normal healing process with no postoperative complications. Favorable outcomes of laser surgery were observed on follow-up sessions. Conclusion: Considering the versatility of the 980 nm diode laser in oral soft tissue surgeries and the advantages of laser surgery, this study suggests the use of 980 nm diode laser in this regard.

  9. Treatment of Ankyloglossia with Carbon Dioxide (CO2) Laser in a Pediatric Patient

    PubMed Central

    Chiniforush, Nasim; Ghadimi, Sara; Yarahmadi, Nazli; Kamali, Abbas

    2013-01-01

    Introduction: Laser surgery as an alternative for conventional surgical procedure has gained special attention. Using Carbon Dioxide (CO2) laser has some benefits like less post-operative pain, swelling and infection, decrease in risk of metastasis and edema, and less bleeding providing dry sites for surgery. Case Report: A 12 years old boy with lingual frenum with indication for excision was referred to the laser department of Tehran University of medical sciences dental school.CO2 laser was used with 10600 nm wavelength, 1.5 W output power, 100 Hz frequency and 400 μsec pulse duration in non-contact mode. Results: The result of using CO2 laser was dry and bloodless field during operation, no post operative swelling, no pain or discomfort, with normal healing process. Conclusion: We suggest and stimulate the use of CO2 laser for soft tissue surgery because of elimination of suture, convenient coagulation, time saving, patients’ comfort and easy manipulation. PMID:25606307

  10. The effect of laterally positioned flap-revised technique and 24% ethylenediaminetetraacetic acid root conditioning on root coverage: A case report.

    PubMed

    Singh, Jagmohan; Bharti, Vipin

    2014-07-01

    Complete root coverage is considered the true goal of treatment of gingival recession defects because only complete coverage assures recovery from the hypersensitivity and esthetic defects associated with recession areas. Previous studies have shown that the laterally positioned flap (LPF) technique or root surface biomodification yields a higher percentage of complete root coverage upon gingival recession treatment. This article highlights the use of the laterally positioned pedicle flap-revised technique (LPFRT) as a modification of the LPF technique, along with 24% EDTA gel as a root surface biomodification agent, in the management of localized gingival recession defects. Clinical examination revealed a Miller class II recession defect on the buccal aspect of the lower right central incisor, as well as the presence of aberrant frenum pull adjacent to the recession defect. The LPFRT, together with 24% EDTA gel, was speculated to cover the gingival recession defect. The frenectomy, along with periosteal fenestration, was planned simultaneously with LPFRT. After 6 months of therapy, the clinical condition was stable with complete root coverage and satisfactory healing of the gingival tissues at both the donor and recipient sites with no signs of inflammation.

  11. Clinical and laboratorial profile and histological features on minor salivary glands from patients under investigation for Sjögren’s syndrome

    PubMed Central

    Pereira, Débora L.; Vilela, Verônica S.; dos-Santos, Teresa C R B.

    2014-01-01

    Diagnosis of Sjögren’s syndrome (SS) is complex and the usefulness of labial minor salivary glands biopsy in this process remains controversial. Objectives: to evaluate the clinical and laboratorial profile and histological features on labial minor salivary glands from patients under investigation of SS. Study Design: clinical charts from 38 patients under suspicion of SS and submitted to labial minor salivary glands biopsies were reviewed. Clinical and laboratorial data were retrieved from the clinical files and the HE-stained histological slides were reviewed under light microscopy. Results: mean age of the patients was 56.5 years and 97% were females; histological analysis showed that 42% of the cases showed ductal dilatation, lymphocytic foci were found in 52.6% and, from this group, 80% of the cases presented a foci/lobules ratio above 0.8. Acinar/ductal ratio was considered diminished in 39.5% of the samples. Thirty six (95%) and 32 (84%) patients, respectively, complained about xerostomia and xerophthalmia. A study of the time interval of the symptoms that led to SS investigation showed a mean of 116 months. Moreover, sixty-six percent of the patients had already been submitted to immunosuppressive therapy prior to the labial minor salivary gland biopsy. Age of the patients, scintigraphic alterations on salivary function, antinuclear factor (ANF), anti-Ro and anti-La did not show statistical significant association with the histological features. Lobules/foci ratio above 0.8 was the only histological parameter statistically associated with Sjögren’s syndrome diagnosis (p<0.0001). Conclusions: in the studied sample, lymphocytic foci on salivary glands were the only histological parameter associated to the diagnosis of SS. Early indication of labial minor salivary gland biopsy to patients under investigation of SS could limit the effects of immunosuppressive therapy on the histological features associated with the evolution of salivary gland involvement

  12. Contour changes in human alveolar bone following tooth extraction of the maxillary central incisor

    PubMed Central

    Li, Bei; Wang, Yao

    2014-01-01

    The purpose of this study was to apply cone-beam computed tomography (CBCT) to observe contour changes in human alveolar bone after tooth extraction of the maxillary central incisor and to provide original morphological evidence for aesthetic implant treatment in the maxillary anterior area. Forty patients were recruited into the study. Each patient had two CBCT scans (CBCT I and CBCT II), one taken before and one taken three months after tooth extraction of maxillary central incisor (test tooth T). A fixed anatomic reference point was used to orient the starting axial slice of the two scans. On three CBCT I axial slices, which represented the deep, middle, and shallow layers of the socket, labial and palatal alveolar bone widths of T were measured. The number of sagittal slices from the start point to the pulp centre of T was recorded. On three CBCT II axial slices, the pulp centres of extracted T were oriented according to the number of moved sagittal slices recorded in CBCT I. Labial and palatal alveolar bone widths at the oriented sites were measured. On the CBCT I axial slice which represented the middle layer of the socket, sagittal slices were reconstructed. Relevant distances of T on the sagittal slice were measured, as were the alveolar bone width and tooth length of the opposite central incisor. On the CBCT II axial slice, which represented the middle layer of the socket, relevant distances recorded in CBCT I were transferred on the sagittal slice. The height reduction of alveolar bone on labial and palatal sides was measured, as were the alveolar bone width and tooth length of the opposite central incisor at the oriented site. Intraobserver reliability assessed by intraclass correlation coefficients (ICCs) was high. Paired sample t-tests were performed. The alveolar bone width and tooth length of the opposite central incisor showed no statistical differences (P<0.05). The labial alveolar bone widths of T at the deep, middle, and shallow layers all showed

  13. Contour changes in human alveolar bone following tooth extraction of the maxillary central incisor.

    PubMed

    Li, Bei; Wang, Yao

    2014-12-01

    The purpose of this study was to apply cone-beam computed tomography (CBCT) to observe contour changes in human alveolar bone after tooth extraction of the maxillary central incisor and to provide original morphological evidence for aesthetic implant treatment in the maxillary anterior area. Forty patients were recruited into the study. Each patient had two CBCT scans (CBCT I and CBCT II), one taken before and one taken three months after tooth extraction of maxillary central incisor (test tooth T). A fixed anatomic reference point was used to orient the starting axial slice of the two scans. On three CBCT I axial slices, which represented the deep, middle, and shallow layers of the socket, labial and palatal alveolar bone widths of T were measured. The number of sagittal slices from the start point to the pulp centre of T was recorded. On three CBCT II axial slices, the pulp centres of extracted T were oriented according to the number of moved sagittal slices recorded in CBCT I. Labial and palatal alveolar bone widths at the oriented sites were measured. On the CBCT I axial slice which represented the middle layer of the socket, sagittal slices were reconstructed. Relevant distances of T on the sagittal slice were measured, as were the alveolar bone width and tooth length of the opposite central incisor. On the CBCT II axial slice, which represented the middle layer of the socket, relevant distances recorded in CBCT I were transferred on the sagittal slice. The height reduction of alveolar bone on labial and palatal sides was measured, as were the alveolar bone width and tooth length of the opposite central incisor at the oriented site. Intraobserver reliability assessed by intraclass correlation coefficients (ICCs) was high. Paired sample t-tests were performed. The alveolar bone width and tooth length of the opposite central incisor showed no statistical differences (P<0.05). The labial alveolar bone widths of T at the deep, middle, and shallow layers all showed

  14. Anesthetic efficacy of infiltrations in mandibular anterior teeth.

    PubMed Central

    Yonchak, T.; Reader, A.; Beck, M.; Clark, K.; Meyers, W. J.

    2001-01-01

    The purpose of this prospective, randomized, double-blind study was to measure the degree of anesthesia obtained with a labial infiltration of either 2% lidocaine with 1:50,000 or 2% lidocaine with 1:100,000 epinephrine in mandibular anterior teeth. Another objective was to measure the degree of anesthesia obtained with a lingual infiltration of 2% lidocaine with 1:100,000 epinephrine in mandibular anterior teeth. Through use of a repeated-measures design, 40 subjects randomly received a labial infiltration at the lateral incisor apex of either 1.8 mL of 2% lidocaine with 1:100,000 epinephrine or 1.8 mL of 2% lidocaine with 1:50,000 epinephrine at 2 separate appointments. An additional 40 subjects received a lingual infiltration at the lateral incisor apex of 1.8 mL of 2% lidocaine with 1:100,000 epinephrine. The mandibular anterior teeth were blindly pulp tested at 4-minute cycles for 60 minutes postinjection. No response from the subject to the maximum output (80 reading) of the pulp tester was used as the criterion for pulpal anesthesia. Anesthesia was considered successful when 2 consecutive 80 readings were obtained. For the 3 infiltrations, success rates for the lateral incisor ranged from 43 to 50%. Adjacent teeth had success rates of 27 to 63%. There was no significant difference (P > 0.05) in success between the labial infiltration of 2% lidocaine with 1:100,000 epinephrine and 2% lidocaine with 1:50,000 epinephrine or the lingual infiltration of 2% lidocaine with 1:100,000 epinephrine when compared with the labial infiltration of 2% lidocaine with 1:100,000 epinephrine. Duration of pulpal anesthesia declined steadily for all solutions over the 60 minutes. In conclusion, the success rate of 43-50% and declining duration of pulpal anesthesia over an hour indicates that a labial infiltration of 1.8 mL of either 2% lidocaine with 1:100,000 epinephrine or 1: 50,000 epinephrine or a lingual infiltration of 2% lidocaine with 1:100,000 epinephrine over the

  15. Bone strains around immediately loaded implants supporting mandibular overdentures in human cadavers.

    PubMed

    Akça, Kivanç; Akkocaoglu, Murat; Cömert, Ayhan; Tekdemir, Ibrahim; Cehreli, Murat Cavit

    2007-01-01

    To compare the biomechanical effect of splinted versus unsplinted mandibular implants supporting overdentures subjected to experimental static immediate load on bone tissue deformation using strain gauge analysis. Strain gauges were bonded on the labial cortical bone adjacent to 2 Straumann dental implants placed in the mandibular interforaminal region of 4 completely edentulous mandibles of fresh human cadavers. The installation torque value (ITV) of each implant was measured using a custom-made torque wrench, and implant stability quotients (ISQs) were also obtained using resonance frequency analysis. Three overdentures (ODs), 2 splinted (bar- and cantilevered bar-retained) and 1 unsplinted (ball-retained), were fabricated for each edentulous mandible. Two experimental loads were applied subsequently via 2 miniature load cells that were placed bilaterally 10 mm (anterior loading) and 15 mm (posterior loading) from the implant. Strain measurements were performed at a sample rate of 10 KHz and under a maximum experimental static load of 100 N; they were simultaneously monitored from a computer connected to a data acquisition system. Finally, the removal torque values (RTV) of the implants were measured. Strains on the labial cortical bone around implants supporting mandibular ODs under anterior loading were significantly higher than measured under posterior loading for all attachment types (P < .05). All strain values were compressive in nature, and the minimum strain (-19 microepsilon) was recorded for bar-retained ODs under 25 N posterior loading, while the maximum strain (-797 microepsilon) was for recorded for retentive anchor-retained ODs under 100 N anterior loading. Nonparametric correlations between ISQs, ITVs, and RTVs identified significant correlations only for ITVs and RTVs (P < .05). Splinting of 2 interforaminal dental implants, regardless of attachment type, to support mandibular ODs subjected to immediate load significantly reduced initial bone

  16. Speech motor control and acute mountain sickness

    NASA Technical Reports Server (NTRS)

    Cymerman, Allen; Lieberman, Philip; Hochstadt, Jesse; Rock, Paul B.; Butterfield, Gail E.; Moore, Lorna G.

    2002-01-01

    BACKGROUND: An objective method that accurately quantifies the severity of Acute Mountain Sickness (AMS) symptoms is needed to enable more reliable evaluation of altitude acclimatization and testing of potentially beneficial interventions. HYPOTHESIS: Changes in human articulation, as quantified by timed variations in acoustic waveforms of specific spoken words (voice onset time; VOT), are correlated with the severity of AMS. METHODS: Fifteen volunteers were exposed to a simulated altitude of 4300 m (446 mm Hg) in a hypobaric chamber for 48 h. Speech motor control was determined from digitally recorded and analyzed timing patterns of 30 different monosyllabic words characterized as voiced and unvoiced, and as labial, alveolar, or velar. The Environmental Symptoms Questionnaire (ESQ) was used to assess AMS. RESULTS: Significant AMS symptoms occurred after 4 h, peaked at 16 h, and returned toward baseline after 48 h. Labial VOTs were shorter after 4 and 39 h of exposure; velar VOTs were altered only after 4 h; and there were no changes in alveolar VOTs. The duration of vowel sounds was increased after 4 h of exposure and returned to normal thereafter. Only 1 of 15 subjects did not increase vowel time after 4 h of exposure. The 39-h labial (p = 0.009) and velar (p = 0.037) voiced-unvoiced timed separations consonants and the symptoms of AMS were significantly correlated. CONCLUSIONS: Two objective measures of speech production were affected by exposure to 4300 m altitude and correlated with AMS severity. Alterations in speech production may represent an objective measure of AMS and central vulnerability to hypoxia.

  17. Speech motor control and acute mountain sickness

    NASA Technical Reports Server (NTRS)

    Cymerman, Allen; Lieberman, Philip; Hochstadt, Jesse; Rock, Paul B.; Butterfield, Gail E.; Moore, Lorna G.

    2002-01-01

    BACKGROUND: An objective method that accurately quantifies the severity of Acute Mountain Sickness (AMS) symptoms is needed to enable more reliable evaluation of altitude acclimatization and testing of potentially beneficial interventions. HYPOTHESIS: Changes in human articulation, as quantified by timed variations in acoustic waveforms of specific spoken words (voice onset time; VOT), are correlated with the severity of AMS. METHODS: Fifteen volunteers were exposed to a simulated altitude of 4300 m (446 mm Hg) in a hypobaric chamber for 48 h. Speech motor control was determined from digitally recorded and analyzed timing patterns of 30 different monosyllabic words characterized as voiced and unvoiced, and as labial, alveolar, or velar. The Environmental Symptoms Questionnaire (ESQ) was used to assess AMS. RESULTS: Significant AMS symptoms occurred after 4 h, peaked at 16 h, and returned toward baseline after 48 h. Labial VOTs were shorter after 4 and 39 h of exposure; velar VOTs were altered only after 4 h; and there were no changes in alveolar VOTs. The duration of vowel sounds was increased after 4 h of exposure and returned to normal thereafter. Only 1 of 15 subjects did not increase vowel time after 4 h of exposure. The 39-h labial (p = 0.009) and velar (p = 0.037) voiced-unvoiced timed separations consonants and the symptoms of AMS were significantly correlated. CONCLUSIONS: Two objective measures of speech production were affected by exposure to 4300 m altitude and correlated with AMS severity. Alterations in speech production may represent an objective measure of AMS and central vulnerability to hypoxia.

  18. [Measurement of orthodontic forces exerted on the upper right central incisor with the increase of the distance of tooth movement and thickness of the aligner].

    PubMed

    Ren, Chaochao; Li, Xiaowei; Wang, Zheyao; Wang, Hongmei; Bai, Yuxing

    2014-03-01

    To measure the orthodontic forces exerted on the upper right central incisor with the increase of the distance of tooth movement and the thickness of the aligner. The labial movement of upper right central incisor at various distances (0.3, 0.6, 0.9, 1.2, 1.5, 1.8 mm) was designed and the stereolithography model (2 times bigger than the original model) was created with 3-D scanning and tomography output. These models were used to fabricate the aligners with different thicknesses (0.8, 1.0, 1.5 and 2.0 mm) of the thermoplastic materials (6 samples for various distances of tooth movement and thicknesses). Orthodontic forces exerted on the upper right central incisor were measured with the micro-stress sensor measurement system. The orthodontic forces increased with the increase of the thickness of the aligner at the same distance of tooth movement (P < 0.05). The orthodontic force was (1.237 ± 0.082), (1.543 ± 0.059), (3.602 ± 0.102), (6.734 ± 0.063) N when the labial movement of upper right central incisor was 0.3 mm with the aligner of 0.8, 1.0, 1.5, 2.0 mm. The orthodontic forces also increased with the increase of the distance of the tooth movement at the same thickness of the aligner(P < 0.05). The orthodontic force of the aligner of 0.8 mm were (1.354 ± 0.039), (1.288 ± 0.037), (1.479 ± 0.031), (1.799 ± 0.039) N when the upper right central tooth labial movement at 0.6, 0.9, 1.2, 1.5 mm. The orthodontic forces increased with the increase of the distance of tooth movement and the thickness of the aligner.

  19. Tissue distribution of a coliphage and Escherichia coli in mussels after contamination and depuration.

    PubMed Central

    Power, U F; Collins, J K

    1990-01-01

    Experiments were undertaken to determine the tissue distribution of Escherichia coli and a coliphage after contamination of the common mussel (Mytilus edulis). Mussels were contaminated with high levels of feces-associated E. coli and a 22-nm icosahedral coliphage over a 2-day period in a flowing-seawater facility. After contamination, individual tissues were carefully dissected and assayed for E. coli and the coliphage. Contaminated mussels were also analyzed to determine the tissue distribution of the contaminants after 24- and 48-h depuration periods. The majority of each contaminant was located in the digestive tract (94 and 89% of E. coli and coliphage, respectively). Decreasing concentrations were found in the gills and labial palps, foot and muscles, mantle lobes, and hemolymph. Our results indicate that contamination above levels in water occurred only in the digestive tract. Contaminated mussels were depurated in a commercial-scale recirculating UV depuration system over a 48-h period. The percent reductions of E. coli occurred in the following order: digestive tract, hemolymph, foot and muscles, mantle lobes, and gills and labial palps. The percent reductions of the coliphage were different, occurring in the following order: hemolymph, foot and muscles, gills and labial palps, mantle lobes, and digestive tract. Our results clearly demonstrate that E. coli and the coliphage are differentially eliminated from the digestive tract. The two microorganisms are eliminated at similar rates from the remaining tissues. Our results also clearly show that the most significant coliphage retention after depuration for 48 h is in the digestive tract. Thus, conventional depuration practices are inappropriate for efficient virus elimination from mussels. PMID:2180372

  20. The principle of rotation advancement for repair of unilateral complete cleft lip and nasal deformity: technical variations and analysis of results.

    PubMed

    Mulliken, J B; Martínez-Pérez, D

    1999-10-01

    This is an assessment of one surgeon's 15-year experience (1981-1995) using the Millard rotation-advancement principle for repair of unilateral complete cleft lip and nasal deformity. All infants underwent a prior labio-nasal adhesion. Since 1991, dentofacial orthopedics with a pin-retained (Latham) appliance was used for infants with a cleft of the lip and palate. Technical variations are described, including modifications in sequence of closure. A high rotation and releasing incision in the columella lengthens the medial labial element and produces a symmetric prolabium with minimal transgression of the upper philtral column by the advancement flap. Orbicularis oris muscle is everted, from caudad to cephalad, to form the philtral ridge. A minor variation of unilimb Z-plasty is used to level the cleft side of Cupid's bow handle, and cutaneous closure proceeds superiorly from this junction. The dislocated alar cartilage is visualized though a nostril rim incision and suspended to the ipsilateral upper lateral cartilage. Symmetry of the alar base is addressed in three dimensions, including maneuvers to position the deviated anterior-caudal septum, configure the sill, and efface the lateral vestibular web. Secondary procedures were analyzed in 105 consecutive patients, both revised (n = 30) and unrevised (n = .75). The possible need for revision in the latter group was determined by panel assessment of six indicators of nasolabial asymmetry, documented by frontal and submental photographs. In the entire study period, a total of 80 percent of children required or will need nasal revision, and a total of 42 percent required or will require labial revision. In the last 5 years, as compared with the earlier decade, there was a significantly diminished incidence of patients requiring labial revision (54 percent to 21 percent) and alar suspension (63 percent to 32 percent). These improvements are attributable to technical refinements and experience, although dentofacial

  1. Analysis and classification of the upper lip aesthetic unit.

    PubMed

    Raphael, Peter; Harris, Ryan; Harris, Scott W

    2013-09-01

    Disharmonies of the upper lip aesthetic unit generally stem from tall ergotrids and/or thin lips. Comprehension and correction of such defects has been stifled by a lack of metrics and organized systems of diagnosis and treatment. The philtral-labial score was devised to better analyze the upper lip region. Measurements were made with Adobe Photoshop CS6, and computations were performed on a standard calculator. A retrospective medical records review identified 908 patients of the senior authors' (P.R. and S.W.H.) practices who underwent perioral rejuvenation between January 1, 2001, and July 31, 2012. Two hundred patients were randomly selected and assessed for disharmonies in three surveys that sequentially built on data points provided. When preoperative anteroposterior and lateral photographs, dental show measurements, and philtral-labial scores were available, diagnostic concordance between the authors approached 100 percent. Pattern analysis resulted in a classification system (labral classification system), designating patients as either type 0 (no defects), type 1 (thin upper lip), type 2 (long philtrum), or type 3 (both) defects. Characteristic dental show values, philtral-labial scores, and suggested treatments were paired with each type. The labral classification system and its associated analytical tools serve as useful references in consultation, simplify discussion of patients with upper lip defects, furnish a practical alternative to complex algorithms, enable documentation of changes, and facilitate analysis of large sample sizes. When implemented judiciously, the tools described in this article will help surgeons confidently address upper lip problems by streamlining accurate diagnosis and guiding proper treatment.

  2. Morphological Symmetry of Maxillary Anterior Teeth before and after Prosthodontic Planning: Comparison between Conventional and Digital Diagnostic Wax-Ups.

    PubMed

    Abduo, Jaafar

    2016-01-01

    The aim of this study was to evaluate the impact of different prosthodontic planning methods on the morphological symmetry of maxillary anterior teeth. In 13 patients receiving fixed prosthodontic treatment, dental models were obtained from the Oral Health Centre of Western Australia. Two forms of diagnostic prosthodontic planning were executed: conventional wax-up and digital wax-up. The asymmetry was evaluated at two levels: tooth morphological asymmetry (TMA) and anterior segment morphological asymmetry (ASMA). For the TMA, the labial surface of each anterior tooth was superimposed on a mirror image of the contralateral tooth. The ASMA involved superimposition of the combined labial surface of all the anterior teeth on one side on the mirror image of the combined labial surface of the contralateral side. For each asymmetry, the discrepancies in the form of 3D Euclidean distances were calculated and statistically evaluated by the Kruskal-Wallis test (p = 0.05). At the TMA level, the digital wax-up models had significantly less asymmetry (p < 0.00) than the pre-treatment and conventional wax-up models. The pre-treatment and conventional wax-up models had similar asymmetry (p = 0.35). However, at the ASMA level, the difference between the models was insignificant (p > 0.05). In this study, the single tooth symmetry had improved after the digital wax-up. However, the conventional wax-up had a minimal impact on single tooth symmetry. ASMA was minimally affected by the two wax-ups. © 2016 S. Karger AG, Basel.

  3. Treatment of mucocutaneous presentations of herpes simplex virus infections.

    PubMed

    Nikkels, Arjen F; Pièrard, Gérald E

    2002-01-01

    Infections by herpes simplex virus (HSV) types I and II are diverse and quite frequent. After primary infection, the virus establishes a life-long latency in the sensory ganglia and recrudescences may occur at an unpredictable rate. Recurrent labial and genital herpes infections represent the majority of clinical manifestations of HSV infections. Their management is currently well established using evidence-based medicine data. Primary labial herpes is generally not treated with antivirals in otherwise healthy children, although intravenous aciclovir may be offered in severe primary infections, particularly in the immunocompromised patient. The decision whether or not to treat recurrent labial herpes should be evaluated individually and depends on the frequency and severity of relapses, the impairment of the quality of life, and the cost of therapy. Patients with mild disease may benefit from topical therapy, and those with severe and frequent recurrences may be considered for intermittent or long-term oral antiviral therapy. Primary genital herpes is treated with oral or intravenous antivirals, depending on the severity of the infection and associated symptoms. Recurrent genital herpes can be managed with episodic short courses of oral antivirals in patients whose recurrences are moderate to severe and rare, and have a clear prodrome. Patients with >5 episodes/year, severe recurrences or unrecognisable prodromes may be best managed with long-term suppressive antiviral prophylaxis. HSV is also responsible for a variety of other clinical manifestations, including herpetic whitlow, neonatal infection, disseminated and atypical cutaneous infections, traumatic herpes, eczema herpeticum, and HSV-associated erythema multiforme. HSV infection may also represent a complication following cosmetic procedures of the oro-facial region, surgical and dental interventions, sun exposure and burns. Precise treatment guidelines for these HSV infections are not firmly established.

  4. Alveolar Ridge Contouring with Free Connective Tissue Graft at Implant Placement: A 5-Year Consecutive Clinical Study.

    PubMed

    Hanser, Thomas; Khoury, Fouad

    2016-01-01

    This study evaluated volume stability after alveolar ridge contouring with free connective tissue grafts at implant placement in single-tooth gaps. A total of 52 single-tooth gaps with labial volume deficiencies in the maxilla (incisors, canines, and premolars) were consecutively treated with implants and concomitant free palatal connective tissue grafts in 46 patients between 2006 and 2009. Implants had to be covered with at least 2 mm peri-implant local bone after insertion. At implant placement, a free connective tissue graft from the palate was fixed inside a labial split-thickness flap to form an existing concave buccal alveolar ridge contour due to tissue volume deficiency into a convex shape. Standardized volumetric measurements of the labial alveolar contour using a template were evaluated before connective tissue grafting and at 2 weeks, 1 year, and 5 years after implantprosthetic incorporation. Tissue volume had increased significantly (P < .05) in all six reference points representing the outer alveolar soft tissue contour of the implant before connective tissue grafting to baseline (2 weeks after implant-prosthetic incorporation). Statistically, 50% of the reference points (P > .05) kept their volume from baseline to 1 year after prosthetic incorporation and from baseline to 5 years after prosthetic incorporation, respectively, whereas reference points located within the area of the implant sulcus showed a significant (P < .05) decrease in volume. Clinically, 5 years after prosthetic incorporation the originally concave buccal alveolar contour was still convex in all implants, leading to a continuous favorable anatomical shape and improved esthetic situation. Intraoral radiographs confirmed osseointegration and stable peri-implant parameters with a survival rate of 100% after a follow-up of approximately 5 years. Implant placement with concomitant free connective tissue grafting appears to be an appropriate long-term means to contour preexisting buccal

  5. Photographic Facial Soft Tissue Analysis by Means of Linear and Angular Measurements in an Adolescent Persian Population

    PubMed Central

    Moshkelgosha, Vahid; Fathinejad, Sheida; Pakizeh, Zeinab; Shamsa, Mohammad; Golkari, Ali

    2015-01-01

    Objective : To obtain objective average measurements of the profile and frontal facial soft tissue to be used as a guide for aesthetic treatment goals. Methods and Materials : This observational study included 110 females and 130 males high school students aged 16-18 years. None of the subjects had any facial deformities. All of them and their parents gave consent to take part in this study. In each case, two standard photographs of profile and frontal views were taken 27 landmarks were digitized on photographs. The mean, standard deviation, and range for a total of 43 facial indices were calculated digitally by computer software. The Student’s t-test was used to compare males and females. Results : The ratio between the lower and middle facial thirds was one to one, but the height of the upper facial third was proportionally smaller than the other two-thirds in both sexes. Boys had greater nasal length, depth, and prominence than girls with statistically significant differences. Both upper and lower lips were more prominent in girls than in boys. All measurements of the chin showed sexual dimorphism characterized by greater chin height and prominence and deeper mentolabial sulcus. Boys had greater facial dimensions than girls. Mouth width, nasal base width, and intercanthal distance were significantly greater in boys. Conclusion : The labial, nasal, and chin areas showed sexual dimorphism in most of the parameters used in this study. Boys had larger faces, greater facial heights, longer nasal, labial, and chin lengths, and greater nasal, labial, and chin prominence. PMID:26464606

  6. Comparing the effect of diode laser against acyclovir cream for the treatment of herpes labialis.

    PubMed

    Honarmand, Marieh; Farhadmollashahi, Leila; Vosoughirahbar, Ehsan

    2017-06-01

    Recently alternative therapies such as the use of diode laser therapy have been introduced for recurrent herpes labial infection. The aim of this study was to evaluate the effectiveness of diode laser for treatment of recurrent herpes labialis. This was single-blind randomized clinical trial to evaluate the efficacy of diode laser for the treatment of recurrent herpes labial. In total, 60 patients whit recurrent herpes simplex labialis were selected and randomly divided in to three groups. 20 patients received treatment whit diode laser (at a wavelength of 870 nm, energy density 4.5 j/cm2), 20 patients were treated with acyclovir cream 5%, 20 patients received treatment with laser-off (placebo). The end point was lesions crusting. Data analyzed by Tukey HSD Test and One-way ANOVA (at a significance level of 0.05) in SPSS-20 software. The mean length of recovery time (day) in the laser, off laser, and acyclovir groups was 2.20±0.41, 4.30±1.03, and 3.4±1.142, respectively. There is a significant difference between three groups in this regard (P<0.0001). The mean duration of pain (day) was 1.35±0.74, 2.65±1.27, and 2.30±0.92 for laser, off laser, and acyclovir groups, respectively (P<0.0001). Treatment with diode laser reduced the length of recovery time and pain severity faster than treatment with acyclovir cream. Key words:Recurrent herpes labial, Acyclovir, Low level laser therapy.

  7. Unique features of pedicellate attachment of the upper jaw teeth in the adult gobiid fish Sicyopterus japonicus (Teleostei, Gobiidiae): morphological and structural characteristics and development.

    PubMed

    Sahara, Noriyuki; Moriyama, Keita; Iida, Midori; Watanabe, Shun

    2013-05-01

    Sicyopterus japonicus (Teleostei, Gobiidae), a hill-stream herbivorous gobiid fish, possesses an unusual oral dentition among teleost fishes on account of its feeding habitat. By using scanning electron microscopy, light microscopy, and transmission electron microscopy, including vital staining with tetracycline, we examined the development of the attachment tissues of the upper jaw teeth in this fish. The functional teeth of S. japonicus had an asymmetrical dentine shaft. The dentine shaft attached to the underlying uniquely shaped pedicel by means of two different attachment mechanisms. At the lingual base, collagen fiber bundles connected the dentine shaft with the pedicel (hinged attachment), whereas the labial base articulated with an oval-shaped projection of the pedicel (articulate attachment). The pedicel bases were firmly ankylosed to the crest of the thin flange of porous spongy bone on the premaxillary bone, which afforded a flange-groove system on the labial surface of the premaxillary bone. Developmentally, the pedicel and thin flange of spongy bone were completely different mineralized attachment tissues. The pedicel had a dual origin, i.e., the dental papilla cells, which differentiated into odontoblasts that constructed the internal surface of the pedicel, and the mesenchymal cells, which differentiated into osteoblasts that formed the outer face of the pedicel. A thin flange of spongy bone was deposited on the superficial resorbed labial side of the premaxillary bone proper, and later rapid bone remodeling proceeded toward the pedicel base. These unique features of pedicellate tooth attachment for the upper jaw teeth in the adult S. japonicus are highly modified teeth for enhancing the ability of individual functional teeth to move closely over irregularities in the rock surfaces during the scraping of algae. Copyright © 2012 Wiley Periodicals, Inc.

  8. The Grooved Rodent Incisor Recapitulates Rudimentary Teeth Characteristics of Ancestral Mammals.

    PubMed

    Li, L; Tang, Q; Jung, H-S

    2016-07-01

    It is known from the paleontology studies of eutherian mammals that incisor numbers were reduced during evolution. The evolutionary lost incisors may remain as vestigial structures at embryonic stages. The recapitulation of the incisor patterns among mammalian species will potentially uncover the mechanisms underlying the phenotypic transition of incisors during evolution. Here, we showed that a minute tooth formed in the presumptive groove region of the gerbil upper incisor at the early developmental stages, during which multiple epithelial swellings and Shh transcription domains spatiotemporally appeared in the dental epithelium, suggests the existence of vestigial dental primordia. Interestingly, when we trimmed the surrounding mesenchyme from incisor tooth germs at or before the bud stage prior to ex vivo culture, the explants developed different incisor phenotypes ranging from triplicated incisors, duplicated incisors, to Lagomorpha-like incisors, corresponding to the incisor patterns in the eutherian mammals. These results imply that the phenotypic transition of incisors during evolution, as well as the achievement of ultimate incisors in adults, arose from differential integrations of primordia. However, when the incisor tooth germ was trimmed at the cap stage, a grooved incisor developed similar to the normal condition. Furthermore, the incisor tooth germ developed a small but smooth incisor after the additional removal of the minute tooth and a lateral rudiment. These results suggest that multiple dental primordia integrated before the cap stage, with the labial primordia contributing to the labial face of the functional incisor. The minute tooth that occupied the boundary of the 2 labial primordia might be implicated in the groove formation. This study sheds light on how rudiments incorporate into functional organs and aids the understanding of incisor evolution.

  9. Exocrine glands of Lepeophtheirus salmonis (Copepoda: Caligidae): Distribution, developmental appearance, and site of secretion.

    PubMed

    Øvergård, Aina-Cathrine; Hamre, Lars A; Harasimczuk, Ewa; Dalvin, Sussie; Nilsen, Frank; Grotmol, Sindre

    2016-12-01

    Exocrine glands of blood-feeding parasitic copepods are believed to be important in host immune response modulation and inhibition of host blood coagulation, but also in the production of substances for integument lubrication and antifouling. In this study, we aimed to characterize the distribution of different types of salmon louse (Lepeophtheirus salmonis) exocrine glands and their site of secretion. The developmental appearance of each gland type was mapped and genes specifically expressed by glands were identified. Three types of tegumental (teg 1-3) glands and one labial gland type were found. The first glands to appear during development were teg 1 and teg 2 glands. They have ducts extending both dorsally and ventrally suggested to be important in lubricating the integument. Teg 1 glands were found to express two astacin metallopeptidases and a gene with fibronectin II domains, while teg 2 glands express a heme peroxidase. The labial glands were first identified in planktonic copepodids, with reservoirs that allows for storage of glandular products. The last gland type to appear during development was named teg 3 and was not seen before the preadult I stage when the lice become more virulent. Teg 3 glands have ducts ending ventrally at the host-parasite contact area, and may secrete substances important for the salmon lice virulence. Salmon lice teg 3 and labial glands are thus likely to be especially important in the host-parasite interaction. Proteins secreted from the salmon louse glands to its salmonid host skin or blood represents a potential interface where the host immune system can meet and elicit effective responses to sea lice antigens. The present study thus represents a fundamental basis for further functional studies and identification of possible vaccine candidates. J. Morphol. 277:1616-1630, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  10. Characteristics of the saliva flow rates of minor salivary glands in healthy people.

    PubMed

    Wang, Zhen; Shen, Ming-Ming; Liu, Xiao-Jing; Si, Yan; Yu, Guang-Yan

    2015-03-01

    To investigate the normal range and characteristics of saliva secretion in the minor salivary glands (MSGs). The flow rates of MSGs were measured in 4 anatomical locations of oral mucosa, and the relationship between MSG flow rates and whole saliva flow rates were assessed in 300 healthy subjects stratified by age and sex. An additional 30 young females were further evaluated for flow symmetry, effects of stimulation, circadian effects in MSGs, and the relationship with the flow rates of major salivary glands. (1) The mean saliva flow rates were 2.10 ± 0.66 (lower labial glands), 2.14 ± 0.62 (upper labial glands), 2.88 ± 0.72 (buccal glands) and 2.15 ± 0.51 (palatal glands) μl/min/cm(2), respectively. The flow rate of buccal glands was significantly higher than the rates of SMGs in other locations (P < 0.01). (2) 5-year-old children had the lowest MSG flow rates (P < 0.0001) while the 10-14-year-old group had the highest (P < 0.001). (3) MSG flow rates were independent of sex (P > 0.05), right vs. left (P > 0.05), and citric acid (2.5%) stimulation (P > 0.05). (4) Only labial MSG displayed a significant secretory circadian rhythm with the highest rate in the evening (P < 0.05). (5) A weak correlation was found between the flow rate of palatal glands and that of unstimulated whole saliva (r = 0.195, P = 0.007). Our findings provide a reference for functional evaluation of MSGs and for donor site selection of MSG transplantation for treatment of severe dry eye syndrome. Copyright © 2014 Elsevier Ltd. All rights reserved.

  11. Expression of Ro/SS-A and La/SS-B determined by immunohistochemistry in healthy, inflamed and autoimmune diseased human tissues: a generalized phenomenon.

    PubMed

    van Woerkom, J M; Geertzema, J G N; Nikkels, P G J; Kruize, A A; Smeenk, R J T; Vroom, T M

    2004-01-01

    Autoantibodies to the ribonucleoproteins Ro/SS-A and La/SS-B are found in autoimmune diseases such as primary Sjögren's syndrome (pSS), systemic lupus erythematousus and rheumatoid arthritis. Increased and aberrant expression of Ro/SS-A and La/SS-B in target organs, which have been reported in the recent literature, might contribute to their antigenicity. However, data on the expression of Ro/SS-A and La/SS-B in other inflammatory conditions are scarce. Using monoclonal antibodies against Ro/SS-A and La/SS-B, we studied the expression of these antigens in paraffin-embedded healthy tissue, aspecific inflamed tissue, the neonatal and adult cardiac conduction systems and labial salivary gland tissues of patients suspected of having pSS. In healthy tissues, the nuclei expressed both Ro/SS-A and La/SS-B. This expression was stronger in inflamed tissues. Nucleoli were negative and cytoplasmic expression was weaker than nuclear expression. No increased or aberrant expression of Ro/SS-A or La/SS-B was observed in either neonatal or adult atrioventricular nodes and bundle branches. More pSS patients showed high La/SS-B immunoreactivity levels in their labial salivary gland ductal cell nuclei than non-Sjögren's syndrome sicca patients. Ro/SS-A and La/SS-B expression is a generalized cell biological phenomenon and may be upregulated by increased cell activation both in aspecific and autoimmune-mediated inflammation. In pSS the high expression of La/SS-B in labial salivary, gland ductal cell nuclei might contribute to the local immune response.

  12. Cephalometric evaluation in different phases of Jasper jumper therapy.

    PubMed

    Herrera, Francyle Simões; Henriques, José Fernando Castanha; Janson, Guilherme; Francisconi, Manoela Favaro; de Freitas, Karina Maria Salvatore

    2011-08-01

    The aim of this study was to evaluate the dentoskeletal and soft-tissue effects of Class II malocclusion treatment with the Jasper jumper followed by Class II elastics at the different stages of therapy. The sample comprised 24 patients of both sexes (11 boys, 13 girls) with an initial age of 12.58 years, treated for a mean period of 2.15 years. Four lateral cephalograms were obtained of each patient in these stages of orthodontic treatment: at pretreatment (T1), after leveling and alignment (T2), after the use of the Jasper jumper appliance and before the use of Class II intermaxillary elastics (T3), and at posttreatment (T4). Thus, 3 treatment phases could be evaluated: leveling and alignment (T1-T2), use of the Jasper jumper (T2-T3), and use of Class II elastics (T3-T4). Dependent analysis of variance (ANOVA) and Tukey tests were used to compare the durations of the 3 treatment phases and for intragroup comparisons of the 4 treatment stages. The alignment phase showed correction of the anteroposterior relationship, protrusion and labial inclination of the maxillary incisors, and reduction of overbite. The Jasper jumper phase demonstrated labial inclination, protrusion and intrusion of the mandibular incisors, mesialization and extrusion of the mandibular molars, reduction of overjet and overbite, molar relationship improvement, and reduction in facial convexity. The Class II elastics phase showed labial inclination of the maxillary incisors; retrusion, uprighting, and extrusion of the mandibular incisors; and overjet and overbite increases. The greatest amount of the Class II malocclusion anteroposterior discrepancy was corrected with the Jasper jumper appliance. Part of the correction was lost during Class II intermaxillary elastics use after use of the Jasper jumper appliance. Copyright © 2011 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  13. Use of amnion as a graft material in vestibuloplasty: a clinical study.

    PubMed

    Kothari, Chaitanya R; Goudar, Gayathri; Hallur, Neelakamal; Sikkerimath, Basavraj; Gudi, Santosh; Kothari, Meenakshi C

    2012-09-01

    The need to cover the exposed periostium has meant that a number of materials including mucosal and skin grafts are regarded as suitable for grafting in oral and maxillofacial surgery. To circumvent the disadvantages of other materials such as skin, biological membranes have been suggested as options, including fetal membrane. The objective of the present study was to evaluate the clinical efficacy of amnion as a graft material for vestibuloplasty, to increase the depth of the sulcus for complete rehabilitation with dentures in 10 patients with a follow up period of 3 months. Ten patients with deficient depth of the mandibular vestibular sulcus who were referred from the Department of Prosthodontics were listed for mandibular labial vestibuloplasty using Clark's technique followed by grafting with amnion over the denuded periostium. The vestibular depth was evaluated at the end of the 1st week, 2nd week, 4th week, and 3rd month postoperatively, and compared with the preoperative vestibular depth. We had no cases of graft necrosis either complete or partial. However, the reduction in the depth of the labial vestibule ranged from 17% to 50% after 3 months' follow up. A mean (SD) labial vestibular depth of 13.3 (1.8)mm was achieved immediately postoperatively, and 10.0 (3.1)mm at 3 months' follow up. We conclude that grafts of amniotic membrane are viable and reliable for covering of the raw surface, prevent secondary contraction after vestibuloplasty, and maintain the postoperative vestibular depth. Copyright © 2011 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  14. Phonotactic acquisition in healthy preterm infants.

    PubMed

    Gonzalez-Gomez, Nayeli; Nazzi, Thierry

    2012-11-01

    Previous work has shown that preterm infants are at higher risk for cognitive/language delays than full-term infants. Recent studies, focusing on prosody (i.e. rhythm, intonation), have suggested that prosodic perception development in preterms is indexed by maturational rather than postnatal/listening age. However, because prosody is heard in-utero, and preterms thus lose significant amounts of prenatal prosodic experience, both their maturation level and their prosodic experience (listening age) are shorter than that of full-terms for the same postnatal age. This confound does not apply to the acquisition of phonetics/phonotactics (i.e. identity and order of consonants/vowels), given that consonant differences in particular are only perceived after birth, which could lead to a different developmental pattern. Accordingly, we explore the possibility that consonant-based phonotactic perception develops according to listening age. Healthy French-learning full-term and preterm infants were tested on the perception of consonant sequences in a behavioral paradigm. The pattern of development for full-term infants revealed that 7-month-olds look equally at labial-coronal (i.e. /pat/) compared to coronal-labial sequences (i.e. /tap/), but that 10-month-olds prefer the labial-coronal sequences that are more frequent in the French lexicon. Preterm 10-month-olds (having 10 months of phonetic listening experience but 7 months of maturational age) behaved as full-term 10-month-olds. These results establish that preterm developmental timing for consonant-based phonotactic acquisition is based on listening age (experience with input). This questions the interpretation of previous results on prosodic acquisition in terms of maturational constraints, and raises the possibility that different constraints apply to the acquisition of different phonological subcomponents. © 2012 Blackwell Publishing Ltd.

  15. Subdivision of mouse vibrissae on an embryological basis, with descriptions of variations in the number and arrangement of sinus hairs and cortical barrels in BALB/c (nu/+; nude, nu/nu) and hairless (hr/hr) strains.

    PubMed

    Yamakado, M; Yohro, T

    1979-06-01

    Development of vibrissae was studied in dd/y mouse embryos by scanning electron microscopy. Arrangement of vibrissae and cortical barrels were also studied by light microscopy in adult dd/y, BALB/c(nu/+), nude (BALB/c, nu/nu) and hairless (hr/hr) mice to find genetic or epigenetic variations. Rudiments of vibrissae first appear on Day 12 of pregnancy as longitudinal ridges on the developing muzzle, and each hair rudiment is represented by a dome on the ridges. The dorsal two rows (A and B; Woolsey and Van der Loos, '70) of mystacial vibrissae are on the lateral nasal prominence, while the ventral three (C, D and E) are on the maxillary prominence. Smaller hairs of mystacial vibrissae appear at the labial part of the maxillary prominenceon Day 13. The rudiments of rhinal hairs also appear at this stage on the part of the muzzle derived from the medial nasal prominence. Thus the so-called mystacial vibrissae should be subdivided into three (or 4, including the rhinal) groups on an embryological basis. They are the lateral nasal, the maxillary and the labial. A supernumerary sinus hair and a corresponding barrel was observed between D and C rows uni-or bilaterally in one third of individuals of BALB/c, nude and hairless mice. It is suggested that supernumerary hairs tend to occur between the groups of hairs as defined above. In nude and hairless mice small barrels representing labial hairs are diminished in number. The number of hair follicles, however, is normal.

  16. [Morphometric evaluation of changes in the alveolar bone of adolescents with bimaxillary protrusion via cone beam computed tomography].

    PubMed

    Yinghong, Liu; Zeyuan, Zhou; Kui, Zhao; Caomin, Tang; Jun, Wang

    2016-02-01

    This study aimed to evaluate the morphometric changes in the alveolar bone of the maxillary and mandibular anterior regions after retraction in adolescents. The sample size comprised 30 adolescent patients with class 1 bimaxillary protrusion (12 males and 18 females, age: 12-18 years old) and were treated by extracting four first pre-molars. Cone beam computed tomography (CBCT) was performed 1 month before and 1 month after the retraction. For each maxillary and mandibular anterior tooth, the labial and palatal alveolar plates at cervical 1/3, middle 1/3, and apical 1/3 levels for bone thickness changes during the retraction of the maxillary and mandibular anterior regions were checked. The movements of cervical 1/3, middle 1/3, and apical 1/3 levels of the maxillary central incisor were measured. Statistical analyses were performed with SPSS 16.0. For the adolescents, alveolar bone thickness increased on the labial side and decreased on the palatal side. The alveolar bone thicknesses of cervical 1/3 and middle 1/3 of maxillary central incisor, cervical 1/3 and apical 1/3 of maxillary lateral incisor, middle 1/3 of mandibular central incisor, apical 1/3 of mandibular lateral incisor, and middle 1/3 and apical 1/3 of mandibular canine all increased after retraction. By contrast, the alveolar bone thickness of the apical 1/3 of maxillary canine and the cervical 1/3 of mandibular canine decreased after retraction. No statistically significant difference was observed in other region. During retraction, a controlled tipping movement occur in adolescents. After retraction, the alveolar bone thickness of the labial side increase, whereas that of the palatal side decrease. Moreover, the thicknesses of major areas in the alveolar bone significantly increase.

  17. The acoustic correlates of secondary articulation in Abkhaz

    NASA Astrophysics Data System (ADS)

    Crouch, Caroline Quigley

    The purpose of this study is to investigate the acoustic correlates of secondary articulation in the Abzhywa dialect of Abkhaz. Data for this study were collected in Sukhum in September of 2014 from four speakers of Abzhywa Abkhaz, two male and two female. Each speaker read a list of 144 words three times, resulting in a total of 1728 words. From these data 151 tokens of word-initial voiceless fricatives were selected for comparison. Tokens belong to one of eight types: retroflex, plain palato-alveolar, labialized palto-alveolar, plain uvular, labialized uvular, palatalized uvular, plain pharyngeal, or labialized pharyngeal. Each token was measured for duration, average intensity, and center of gravity in Praat. Using the 'hclust' clustering function in R, tokens from all eight types were clustered based on the three acoustic measures. Then, fricatives with shared primary places of articulation but different secondary articulations were compared along each of the three acoustic measures. The 'k-means' clustering function was used to cluster tokens sharing a primary place of articulation based on two of the three acoustic measures determined by the function to be the best predictors of token type. This study found that the three acoustic measures used were not sufficient to distinguish the fricatives across places of articulation. For fricatives sharing a primary place of articulation, center of gravity and duration were selected by k-means as the two most relevant components in all three cases. However, the clustering in all cases was not homogenous, indication that further acoustic features are necessary for accurately distinguishing fricatives that share a primary but not a secondary place of articulation.

  18. Double bonding system for deeply impacted tooth--a technic clinic.

    PubMed

    Singh, Gyan P; Tandon, Pradeep; Shastri, Dipti; Verma, Sneh Lata; Verma, Sneh Lata; Verma, Umesh P

    2013-01-01

    Close eruption technique is preferred in deep, buried, intraosseous and labially impacted teeth to provide healthy and fuinctional attached gingiva but in this technique failure of bonded attachment usually means, repeat exposure of the impacted tooth. This article describes an innovative method for bonding two attachments (Double Bonding System) in combination instead of one. It provides the safe and determinate system for ortho-eruption, avoid the trauma of patient from re-exposure and enhance the comfort as well the confidence of the operator.

  19. Aggressive Angiomyxoma of the Pelvis and Perineum: A Case Report and Literature Review

    PubMed Central

    Al-Umairi, Rashid Saif; Kamona, Atheel; Al-Busaidi, Fadhila Mohammed

    2016-01-01

    Aggressive angiomyxoma (AA) is a rare mesenchymal tumor that usually occurs in the pelvis and perineum of young females. AA can simulate Bartholin’s gland cyst, abscess, lipoma, simple labial cyst, or other pelvic soft tissue tumors. Cross-sectional imaging, particularly magnetic resonance imaging (MRI), plays an essential role in the diagnosis and management of AA. We report a case of AA in a 38-year-old woman with typical MRI features. We also present the findings of a literature review on the radiological features of this disease. PMID:27974964

  20. Vertical bone growth following autotransplantation of the developing maxillary third molar to replace a retained mandibular permanent molar: a case report.

    PubMed

    Plakwicz, Paweł; Czochrowska, Ewa Monika; Milczarek, Anna; Zadurska, Malgorzata

    2014-01-01

    A retained permanent mandibular first molar caused arrested development and a defect of the alveolar bone in a 16-year-old girl. Extraction of the ankylosed tooth was immediately followed by autotransplantation of the developing maxillary third molar. At the 3-year follow-up examination the interproximal bone level at the autotransplanted molar was equal to that of the neighboring teeth. Cone beam computed tomography showed bone at the labial aspect of the transplant. The eruption of the autotransplanted tooth stimulated vertical alveolar bone development and repaired the bone defect. Additionally, there was closure of the posterior open bite that was initially present at the ankylosed molar site.

  1. Ulcerative cheilitis in a rhesus macaque.

    PubMed

    Bailey, C C; Miller, A D

    2012-03-01

    A 2-year-old, female, simian immunodeficiency virus E543-infected rhesus macaque (Macaca mulatta) was presented for necropsy following euthanasia due to a history of diarrhea, weight loss, and a small, round ulcer along the left labial commissure. Histopathologic examination of the ulcer revealed infiltration by large numbers of degenerate and nondegenerate neutrophils and macrophages admixed with syncytial epithelial cells. Rare epithelial cells contained herpetic inclusion bodies. These cells stained positive for Human herpesvirus 1 via immunohistochemistry, and DNA sequencing confirmed the presence of closely related Macacine herpesvirus 1 (B virus).

  2. Emergent gingival cyst of the adult.

    PubMed

    Brooks, John K; Kleinman, Justin W; Basile, John R

    2017-01-01

    The gingival cyst of the adult is a relatively rare, benign odontogenic cyst that maintains an insidious growth rate. This article describes a case of a diminutive fibrotic overgrowth arising on the labial interproximal gingiva between the mandibular right canine and first premolar in a 68-year-old woman. Within 1 year, the lesion had increased in size and appeared vesicular. The morphologic changes warranted surgical excision and histopathologic review. The lesion was diagnosed as a gingival cyst. At a 4.5-month recall appointment, there was no evidence of recurrence. Early lesional detection can potentially mitigate mucogingival defects and improve clinical outcomes.

  3. Effects of Er:YAG laser on enamel bonding of composite materials

    NASA Astrophysics Data System (ADS)

    Keller, Ulrich; Hibst, Raimund

    1993-07-01

    Cylinders of microfil light-cured composite resin were bonded to the labial enamel surface of bovine incisor teeth which had previously been subjected to different laser treatments. One part of the tooth surfaces were laser treated in a defocused way only, another part with a different overlaying pattern of focused laser pulses. Specimens were thermocycled and the adhesion of the composites were determined by tensile strength tests. The best results were obtained by laser conditioning of the enamel surface in a defocused way with an overlaying fine pattern of focused single shots. The tensile strength reached 92.5% of the acid etched bonding.

  4. Treatment of gummy smile: Gingival recontouring with the containment of the elevator muscle of the upper lip and wing of nose. A surgery innovation technique

    PubMed Central

    Storrer, Carmen Lucia Mueller; Valverde, Fabiane Kristine Bochenek; Santos, Felipe Rychuv; Deliberador, Tatiana Miranda

    2014-01-01

    The containment of the elevator muscle of the upper lip and wing of nose was used for the treatment of patients with gummy smile. This technique had corrected esthetic alterations of smile, reducing the upper lip elevation, which results in a smaller gingival display. An upper lip lengthening as well as a reduction in the upper lip shortening when the patient smiled could be observed. The high smile line was corrected without compromising the labial harmony. This study presents an innovative and effective therapeutic option to obtain a natural and harmonious smile. The patient expressed a high degree of satisfaction. PMID:25425832

  5. Cheilitis Glandularis: Two Case Reports of Asian-Japanese Men and Literature Review of Japanese Cases

    PubMed Central

    Yanagawa, Toru; Yamaguchi, Akira; Harada, Hiroyuki; Yamagata, Kenji; Ishibashi, Naomi; Noguchi, Masayuki; Onizawa, Kojiro; Bukawa, Hiroki

    2011-01-01

    Cheilitis glandularis (CG) is a rare disorder characterized by swelling of the lip with hyperplasia of the labial salivary glands. CG is most frequently encountered in the lower lip, in middle-aged to older Caucasian men; however Asian cases were rarely reported. In this paper we present two cases of CG in Asian-Japanese men. One was a 23-year-old male with CG of the superficial suppurative type. The other was a 54-year-old male with deep suppurative type. We also reviewed the Japanese cases of CG in the literature and discussed about clinical feature of Japanese CG. PMID:21991474

  6. Split-thickness flap with a semicircular punched-ridge pedicled periosteal flap for implant restoration in highly atrophic patients: a technical note.

    PubMed

    Seemann, Rudolf; Perisanidis, Christos; Traxler, Hannes; Ewers, Rolf

    2014-01-01

    Attached gingiva is a crucial aspect of healthy peri-implant tissue. Severely atrophied jaws have minimal quantities of attached gingiva. Any surgical procedure bears the potential risk of further loss of attached gingiva. The split-thickness flap described here provides excellent access. Using a biopsy punch, the periosteum is easily cut in semicircular fashion on the labial surface of the bone so that it remains pedicled on the lingual or palatal ridge. The split-thickness flap permits fixation of the gingival flap to the periosteum. The periosteal flap is closed with sutures to achieve soft tissue closure over the implants even in case of simultaneous vestibuloplasty.

  7. Divided café-au-lait macule of the mouth.

    PubMed

    Sergay, Amanda; Silverberg, Nanette B

    2007-05-01

    We describe a 4-year-old, otherwise healthy boy with a congenital history of a perioral and labial segmental café-au-lait macule, who was noted to have unilateral localized gingival hyperpigmentation that aligned with the café-au-lait macule. This case is highly illustrative of the embryologic timing of the genetic event locally, which leads to café-au-lait type hyperpigmentation. Because the facial features and the ectoderm overlying the facial muscles develop around the third to fourth week of gestation, the distribution of this café-au-lait macule suggests development at the same time.

  8. Correction of dental Class III with posterior open bite by simple biomechanics using an anterior C-tube miniplate

    PubMed Central

    Ahn, Hyo-Won; Chung, Kyu-Rhim; Kang, Suk-Man; Lin, Lu; Nelson, Gerald

    2012-01-01

    In the correction of dental Class III molar relationship in skeletal Class II patients, uprighting of the mandibular posterior segments without opening the mandible is an important treatment objective. In the case reported herein, a C-tube miniplate fixed to the lower labial symphysis and connected with a nickel-titanium reverse-curved archwire provided effective uprighting of the lower molars, without the need of orthodontic appliances on the mandibular anteriors. Using this approach, an appropriate magnitude of force is exerted on the molars while avoiding any negative effect on the mandibular anteriors. PMID:23173121

  9. Clitoral hemodynamic changes after a topical application of alprostadil.

    PubMed

    Becher, E F; Bechara, A; Casabe, A

    2001-01-01

    We performed duplex ultrasonography of the clitoris to assess the local hemodynamic changes after a topical application of alprostadil. Color duplex ultrasonography was used to evaluate 18 women before and after the application of 1 g of 0.2% alprostadil gel. The peak systolic velocity and end diastolic velocity showed a statistically significant difference after the application. All women showed labial and clitoral engorgement, 72% reported a pleasant sensation of warmth, and no systemic side effects were found. These findings are similar to the values reported after sexual stimulation, indicating that topical vasoactive drugs might help in the differential diagnosis of the vascular component of female sexual dysfunction.

  10. Colovaginoplasty in a case of mayer-rokitansky-kuster-hauser syndrome.

    PubMed

    Saleem, Muhammad; Iqbal, Muhammad Zafar; Jam, Mazher Rafee; Ahmad, Mushtaq; Mirza, Bilal

    2014-01-01

    Mayer-Rokitansky-Kuster-Hauser Syndrome (MRKHS) is characterized by various abnormalities of paramesonephric duct structures; vaginal aplasia being the commonest anomaly in the spectrum. We report a 17-year-old girl; a case of MRKHS with vaginal agenesis. The cervix was present but atretic; uterus, fallopian tubes and ovaries were normal. There were no associated renal or skeletal defects. Colovaginoplasty was done to bridge the gap between uterus and introitus. Postoperatively, small part of colovaginoplasty flap became necrotic posteriorly, which was ultimately managed by insetting of labial flap.

  11. Colovaginoplasty in a Case of Mayer-Rokitansky-Kuster-Hauser Syndrome

    PubMed Central

    Iqbal, Muhammad Zafar; Jam, Mazher Rafee; Ahmad, Mushtaq; Mirza, Bilal

    2014-01-01

    Mayer-Rokitansky-Kuster-Hauser Syndrome (MRKHS) is characterized by various abnormalities of paramesonephric duct structures; vaginal aplasia being the commonest anomaly in the spectrum. We report a 17-year-old girl; a case of MRKHS with vaginal agenesis. The cervix was present but atretic; uterus, fallopian tubes and ovaries were normal. There were no associated renal or skeletal defects. Colovaginoplasty was done to bridge the gap between uterus and introitus. Postoperatively, small part of colovaginoplasty flap became necrotic posteriorly, which was ultimately managed by insetting of labial flap. PMID:24834388

  12. Variations in bone density across the body of the immature human mandible.

    PubMed

    Hutchinson, Erin F; Farella, Mauro; Hoffman, Jakobus; Kramer, Beverley

    2017-03-03

    During growth the mandible accommodates increases in biomechanical loading resulting from changes in the function of structures of the oral cavity. Biomechanical loads are thought to play an intricate and vital role in the modelling and remodelling of bone, with site-specific effects on bone mineral density. It is anticipated that the effects of this loading on bone mineral density are intensified during the functional transition from prenatal to postnatal stages. The aim of this study was thus to evaluate changes in bone mineral density across the body of the immature human mandible during the early stages of dental development. The study sample included 45 human mandibles, subdivided into three age groups: prenatal (30 gestational weeks to birth; n = 15); early postnatal (birth to 12 months; n = 18); and late postnatal (1-5 years; n = 12). Mandibles were scanned using X-ray micro-computed tomography. Eight landmarks were selected along the buccal/labial and lingual surfaces of each dental crypt for evaluation of the bone mineral density. Bone mineral density values were calculated using a reference standard and analysed using multivariate statistics. The bone mineral density of the lingual surface was found to be significantly higher (P ≤ 0.000) than that of the buccal/labial surface. Furthermore, bone mineral density in the alveolar region of the buccal/labial surface of the deciduous central incisor (P ≤ 0.001), the deciduous first molar (P ≤ 0.013) and lingual alveolar area of the deciduous second molar (P ≤ 0.032) were significantly greater in the early postnatal period than in the prenatal period. While changes in bone mineral density across the lingual surface were consistent with the progression of development and the biomechanical demand of the tongue as previously demonstrated, changes observed across the buccal/labial surface of the mandible appeared to accompany the advancing dental development. Thus, changes in bone mineral density across the

  13. Severe Angle Class III skeletal malocclusion associated to mandibular prognathism: orthodontic-surgical treatment

    PubMed Central

    Souki, Marcelo Quiroga

    2016-01-01

    ABSTRACT The present case report describes the orthodontic treatment of a young adult patient (18y / 1m), Class III skeletal malocclusion, with mandibular prognathism and significant dental compensation. The canine relation was Class III, incisors with tendency to crossbite and open bite, moderate inferior crowding, and concave profile. Skeletal correction of malocclusion, facial profile harmony with satisfactory labial relationship, correction of tooth compensation and normal occlusal relationship were obtained with orthodontic treatment associated to orthognathic surgery. This case was presented to the Brazilian Board of Orthodontics and Facial Orthopedics (BBO), as part of the requirements to become a BBO diplomate. PMID:28125146

  14. Socio-Linguistic Factors and Gender Mapping Across Real and Virtual World Cultures

    DTIC Science & Technology

    2012-07-25

    perception of the sound . She cites back vowels and back consonants as being associated with masculinity and labial consonants as being associated with...on   sound   symbolism.   Analysis   shows   that   many   of   the   existing   socio-­‐linguistic   claims  about...in  the  light  of  linguistic  observations   based   on   sound   symbolism   and   naming   conventions.   The

  15. A new species of gecko from arid inland regions of eastern Australia (Diplodactylus; Diplodactylidae).

    PubMed

    Couper, Patrick J; Oliver, Paul M

    2016-03-24

    We describe a new species of small terrestrial gecko in the genus Diplodactylus from inland regions of western Queensland and New South Wales, Australia. Diplodactylus ameyi sp. nov. can be distinguished from its congeners in the Diplodactylus conspicillatus species-group by its relatively large size, bulbous tail which lacks an acute attenuated extension at tip, small first labial scale and comparatively robust head morphology (which includes a broadly rounded snout and no well-defined canthus rostralis). Related populations from eastern and central Queensland currently referred to D. platyurus include further deeply divergent lineages but additional material is required to resolve systematic boundaries in this region.

  16. Dental caries in rural and urban black preschoolchildren.

    PubMed

    Cleaton-Jones, P; Richardson, B D; Rantsho, J M

    1978-05-01

    The dentitions of 439 rural and 192 urban black children aged 1-5 years were examined with mirror and probe. Dental caries was common and the percentage prevalence and dmft values were similar in children of 1-3 years in both groups. At 4 years of age there was a twofold increase in dental caries in the urban children to reach a dmft score significantly greater than that in the rural children (P less than 0.01). Labial caries was common in rural children but rare in urban children while rampant caries (dmft greater than or equal to 5) exhibited the opposite pattern.

  17. Practice Bulletin No. 165: Prevention and Management of Obstetric Lacerations at Vaginal Delivery.

    PubMed

    2016-07-01

    Lacerations are common after vaginal birth. Trauma can occur on the cervix, vagina, and vulva, including the labial, periclitoral, and periurethral regions, and the perineum. Most of these lacerations do not result in adverse functional outcomes. Severe perineal lacerations, extending into or through the anal sphincter complex, although less frequent, are more commonly associated with increased risk of pelvic floor injury, fecal and urinary incontinence, pain, and sexual dysfunction with symptoms that may persist or be present many years after giving birth. The purpose of this document is to provide evidence-based guidelines for the prevention, identification, and repair of obstetric lacerations and for episiotomy.

  18. Practice Bulletin No. 165 Summary: Prevention and Management of Obstetric Lacerations at Vaginal Delivery.

    PubMed

    2016-07-01

    Lacerations are common after vaginal birth. Trauma can occur on the cervix, vagina, and vulva, including the labial, periclitoral, and periurethral regions, and the perineum. Most of these lacerations do not result in adverse functional outcomes. Severe perineal lacerations, extending into or through the anal sphincter complex, although less frequent, are more commonly associated with increased risk of pelvic floor injury, fecal and urinary incontinence, pain, and sexual dysfunction with symptoms that may persist or be present many years after giving birth. The purpose of this document is to provide evidence-based guidelines for the prevention, identification, and repair of obstetric lacerations and for episiotomy.

  19. Minor salivary glands as a major source of secretory immunoglobin A in the human oral cavity.

    PubMed

    Crawford, J M; Taubman, M A; Smith, D J

    1975-12-19

    Secretory immunoglobulin A is the predominant immunoglobulin in labial minor salivary gland secretions. Its mean concentration is four times higher in these secretions than in parotid gland secretion. The minor salivary glands can produce 30 to 35 percent of the immunoglobulin A that enters the oral cavity. This, together with the potential accessibility of these glands to antigenic stimulation, suggest that they may be an important source of the immune factors that are involved in the regulation of the microorganisms in the oral environment.

  20. Lichen sclerosus: a review of literature and a case of an atypic surgical treatment.

    PubMed

    Ziglioli, Francesco; Fornia, Samanta; Ciuffireda, Matteo; Meli, Silvia; Dinale, Francesco; Simonazzi, Marta; Cortellini, Pietro

    2011-04-01

    Lichen sclerosus is a chronic immuno-mediated skin disease of the genital region in men and women. The treatment may be pharmacological or surgical, the choice depending on the extension of the involved area, the histological pattern and the level of functional disease complained by the patient. If the biopsy is negative for neoplastic degeneration the treatment may be pharmacological only. In our paper, we describe the case of a patient with vulvar disease and labial fusion, burial of the clitoris and severe introital stenosis. In this case, the treatment was surgical.

  1. Clinical recommendation: pediatric lichen sclerosus.

    PubMed

    Bercaw-Pratt, Jennifer L; Boardman, Lori A; Simms-Cendan, Judith S

    2014-04-01

    Lichen sclerosus is a chronic inflammatory condition affecting the anogenital region that may present in the prepubertal or adolescent patient. Clinical presentations include significant pruritus, labial adhesions, and loss of pigmentation. Treatment includes topical anti-inflammatory agents and long-term follow-up as there is a high risk of recurrence and an increased risk of vulvar cancer in adult women with history of lichen sclerosus. These recommendations are intended for pediatricians, gynecologists, nurse practitioners and others who care for pediatric/adolescent girls in order to facilitate diagnosis and treatment.

  2. Larva of Palaemnema brasiliensis Machado (Odonata: Platystictidae), from Amazonas, Brazil.

    PubMed

    Neiss, Ulisses Gaspar; Hamada, Neusa

    2016-02-09

    The larva of Palaemnema brasiliensis Machado, 2009 is described and illustrated based on last-instar larvae and exuviae of reared larvae collected in a blackwater stream in Barcelos and Presidente Figueiredo municipalities, Amazonas state, Brazil. The larva of P. brasiliensis can be distinguished from the two South American species of the genus with described larvae (P. clementia Selys and P. mutans Calvert), mainly by presence of a single obtuse cusp on the labial palp, the presence and configuration of setae in the caudal lamellae, and the proportional length of terminal filaments of the caudal lamellae. The family is recorded here for the first time in Brazilian state of Amazonas.

  3. Characteristic and non-characteristic pathological findings in peste des petits ruminants (PPR) of sheep in the Ege district of Turkey.

    PubMed

    Toplu, N

    2004-01-01

    This report describes the pathological and immunohistochemical findings in naturally infected lambs from three outbreaks of peste des petits ruminants in Mugla and Aydin provinces of the Ege district of Turkey. At necropsy, ulcerative stomatitis, catarrhal or fibrinous bronchopneumonia, and acute catarrhal enteritis were observed. Histopathologically, syncytial cells containing inclusion bodies were seen in the tongue and in the buccal, labial and soft palate mucosae. In pneumonic lungs, syncytial cells were present in the alveolar lumina, and cytoplasmic inclusion bodies in epithelial cells of the bronchi and bronchioli. Immunohistochemically, viral antigen was strongly labelled in the lung, oral tissues and small intestine.

  4. Localised enamel hypoplasia of human deciduous canines: genotype or environment?

    PubMed

    Taji, S; Hughes, T; Rogers, J; Townsend, G

    2000-06-01

    A discrete area of defective enamel formation that appears on the labial surface of the crowns of deciduous canine teeth has been described in both recent and prehistoric human populations, with reported frequencies varying from 1 to 45 per cent. Suggestions about the aetiology of this localized hypoplasia range from genotypic factors to environmental conditions and systemic effects. The major aims of this study were to describe the frequency of occurrence and pattern of expression of the lesion in Australian Aboriginal and Caucasian ethnic groups, and to clarify the role of genetic factors by examining a sample of twins. The study sample consisted of dental casts of 181 pairs of Australian Caucasian twins, 215 Aborigines and 122 Caucasian singletons, together with 253 extracted deciduous canines. Examination of dental casts and extracted teeth was undertaken under 2x magnification with emphasis being placed upon location and expression of the lesion. The defect was observed in 49 per cent of twins and 44 per cent of Aborigines, but only 36 per cent of singletons. The percentages of affected teeth in each group were: 18 per cent in twins, 17 per cent in Aborigines and 13 per cent in Caucasians. A significant proportion of the defects occurred on the mesial aspect of the labial surface, in the middle area incisocervically, with the majority in the lower jaw. A number of significant differences in frequency were observed between groups, sexes, arches and sides. The results confirm some of the findings of previous studies, but also suggest that none of environmental, genetic or systemic factors can be ruled out as being involved in aetiology of the defect. The higher incidence of the lesion occurring on the mesial aspect of the labial surface is suggestive of physical trauma. Also, the vulnerability of the prominent developing mandibular canine, with its thin or missing labial covering of bone, would be expected to lead to higher prevalence of the lesion in the lower

  5. Nasoalveolar cyst: an enigma for the dentist

    PubMed Central

    Misra, Satya Ranjan; Gopal, Maragathavalli; Mohanty, Neeta; Rastogi, Varun

    2015-01-01

    A nasoalveolar cyst is a rare, non-odontogenic soft tissue cyst encountered in the anterior maxillary labial sulcus as an asymptomatic soft tissue swelling. Often, patients with these cysts report them to the dental clinic where they are mistaken for odontogenic lesions by the dental surgeon, especially if concomitant dental problems are present. They cannot be detected by routine conventional dental radiography as they are peripheral, lying within the mucosa thereby posing a diagnostic challenge. We document a case of a 47-year-old woman with a nasoalveolar cyst. PMID:25566935

  6. Description of the larva of Gynacantha millardi Selys, 1891 (Odonata: Aeshnidae) from Chhattisgarh, India.

    PubMed

    Dawn, Prosenjit; Chandra, Kailash

    2016-06-29

    The larva of Gynacantha millardi Selys is described here from female larvae and male and female exuviae collected from Chhattisgarh, India. Unlike other Gynacantha larvae known so far, G. millardi has 7 palpal setae almost equal in length; in other species, the palpal setae are of different lengths. The larvae lack a tooth on each side of the median cleft and have a distinct blunt tooth on the inner margin corner of each labial palp. The larvae were found in a semi-stagnant forest pool with enormous growth of aquatic vegetation.

  7. Memoan ciceroi gen. et sp. nov., a remarkable new firefly genus and species from the Atlantic Rainforest (Coleoptera: Lampyridae).

    PubMed

    Da Silveira, Luiz Felipe Lima; Mermudes, José Ricardo M

    2013-01-01

    A species of firefly discovered in a fragile and rapidly disappearing Atlantic Rainforest biome in Brazil does not fit into any of the existing subfamilies nor described generic categories in the Lampyridae and is described here as Memoan ciceroi gen. et sp. nov. and classed as Lampyridae Incertae sedis, as it exhibits features of both the Amydetinae and Lampyrinae. An overview of subfamily arrangements and relevant generic characters is given to support this action. Memoan gen. nov. can be distinguished by its alveolate pronotum and elytra; subserrate antennae, antenommeres II-IX compressed, antennal sockets obliquely inserted on tubercles; labial palp one-segmented and obconic, and by its conspicuous pleuroventral suture.

  8. Distalization of maxillary molars using a lever arm and mini-implant.

    PubMed

    Gurgel, Júlio de Araújo; Pinzan-Vercelino, Célia Regina Maio; Bramante, Fausto Silva; Rivera, Alan Poy

    2013-01-01

    This article describes the orthodontic treatment of a young woman with a Class II malocclusion and maxillomandibular prognathism. One orthodontic mini- implant was placed in the posterior area of the palate to provide anchorage for?a transpalatal arch. The force for molar distalization was applied using an elastic chain from the lever arm inserted on the transpalatal arch to the mini-implant. Two sliding jigs were applied buccally as a complement for Class II malocclusion correction. This system created an efficient mechanotherapy for maxillary molar distalization. The active treatment period was 19 months. Normal overjet and reduction of maxillomandibular prognathism were obtained, and labial balance was improved.

  9. Periductal lymphocytic infiltrates in salivary glands in myasthenia gravis patients lacking Sjögren's syndrome.

    PubMed Central

    Lindahl, G; Lefvert, A K; Hedfors, E

    1986-01-01

    In eight of eleven patients with clinical and serological evidence of myasthenia gravis (MG), immunohistological analysis of biopsies from labial salivary glands (LSG) showed focal periductal lymphocytic infiltrates, mainly composed of anti-Leu 3a+ T helper lymphocytes, a finding usually regarded as indicative for Sjögren's syndrome (SS). None of the patients could however, according to functional criteria, be considered as having SS. This study thus indicates that lymphocytic infiltrates in LSG can be seen in MG, which has been thought of as an organspecific autoimmune disease with symptoms and signs confined to striated muscles. Images Fig. 1 PMID:2948746

  10. Data set for Tifinagh handwriting character recognition

    PubMed Central

    Bencharef, Omar; Chihab, Younes; Mousaid, Nouredine; Oujaoura, Mustapha

    2015-01-01

    The Tifinagh alphabet-IRCAM is the official alphabet of the Amazigh language widely used in North Africa [1]. It includes thirty-one basic letter and two letters each composed of a base letter followed by the sign of labialization. Normalized only in 2003 (Unicode) [2], ICRAM-Tifinagh is a young character repertoire. Which needs more work on all levels. In this context we propose a data set for handwritten Tifinagh characters composed of 1376 image; 43 Image For Each character. The dataset can be used to train a Tifinagh character recognition system, or to extract the meaning characteristics of each character. PMID:26217753

  11. An unusual presentation of talon cusp: a case report.

    PubMed

    Sumer, A P; Zengin, A Z

    2005-10-08

    The talon cusp is a relatively rare dental developmental anomaly characterised by cusp-like projections, usually observed on the lingual surface of the affected tooth. Normal enamel covers the cusp and fuses with the lingual aspect of the tooth. The cusp may or may not contain an extension of the pulp. This occurs in either maxillary or mandibular anterior teeth in both the primary and permanent dentition. This study reports the unusual case of a 47-year-old female with a taloned tooth on the right maxillary central incisor possessing both lingual and labial talons, with an x-shaped appearance when viewed occlusally.

  12. Successful treatment of Miescher's cheilitis in Melkersson-Rosenthal syndrome with betamethasone injections and doxycycline

    PubMed Central

    Oudrhiri, Lamia; Chiheb, Soumiya; Marnissi, Farida; Zamiati, Soumaya; Benchikhi, Hakima

    2012-01-01

    We report a case of a 19-year-old girl who presented with 5-year history of swelling of upper lip and fissured tongue treated with dapsone then oral steroids without any improvement. Clinical examination found peripheral facial nerve paralysis and Labial mucosa biopsy showed non-necrotizing giganto-epithelioid granuloma. Diagnosis of Melkersson-Rosenthal syndrome was retaind because of association of cheilitis, lingua plicata and facial paralysis. Given the failure of dapsone and oral steroid we suggested an association of betamethasone injection and doxycycline. Gradual and permanent reduction of the upper lip volume was observed. One year follow up objectified no reactivation of cheilitis. PMID:23397029

  13. Bumba, a replacement name for Maraca Pérez-Miles, 2005 and Bumba lennoni, a new tarantula species from western Amazonia (Araneae, Theraphosidae, Theraphosinae)

    PubMed Central

    Pérez-Miles, Fernando; Bonaldo, Alexandre Bragio; Miglio, Laura Tavares

    2014-01-01

    Abstract We propose the name Bumba as a new name for Maraca, preoccupied by Maraca Hebard, 1926 (Orthoptera). We describe and illustrate Bumba lennoni, a new theraphosid species from Caxiuanã, Pará, Brazil. This species differs from the other species of the genus in the extremely reduced keel on male palpal organ and in the higher number of labial and maxillary cuspules. Females additionally differ in the spermathecal morphology. As a consequence of the name replacement, three new combinations are established. PMID:25408606

  14. Effect of host plant and immune challenge on the levels of chemosensory and odorant-binding proteins in caterpillar salivary glands.

    PubMed

    Celorio-Mancera, Maria de la Paz; Ytterberg, A Jimmy; Rutishauser, Dorothea; Janz, Niklas; Zubarev, Roman A

    2015-06-01

    More than half of the proteome from mandibular glands in caterpillars is represented by chemosensory proteins. Based on sequence similarity, these proteins are putative transporters of ligands to gustatory receptors in sensory organs of insects. We sought to determine whether these proteins are inducible by comparing, both qualitatively and quantitatively, the salivary (mandibular and labial) proteomes from caterpillars (Vanessa cardui) reared on different plants and artificial diet containing either bacteria or bacterial cell-walls. We included a treatment where the caterpillars were switched from feeding on artificial diet to plant material at some point in their development. Additionally, we evaluated the degree of overlap between the proteomes in the hemolymph-filled coelom and salivary glands of caterpillars reared on plant material. We found that the quality and quantity of the identified proteins differed clearly between hemolymph-filled coelome, labial and mandibular glands. Our results indicated that even after molting and two-day feeding on a new diet, protein production is affected by the previous food source used by the caterpillar. Candidate proteins involved in chemosensory perception by insects were detected: three chemosensory (CSPs) and two odorant-binding proteins (OBPs). Using the relative amounts of these proteins across tissues and treatments as criteria for their classification, we detected hemolymph- and mandibular gland-specific CSPs and observed that their levels were affected by caterpillar diet. Moreover, we could compare the protein and transcript levels across tissues and treatment for at least one CSP and one OBP. Therefore, we have identified specific isoforms for testing the role of CSPs and OBPs in plant and pathogen recognition. We detected catalase, immune-related protein and serine proteases and their inhibitors in high relative levels in the mandibular glands in comparison to the labial glands. These findings suggest that the

  15. Oral focal epithelial hyperplasia: report of five cases.

    PubMed

    Borborema-Santos, Cristina Maria; Castro, Maria Marta de; Santos, Paulo José Benevides dos; Talhari, Sinésio; Astolfi-Filho, Spartaco

    2006-01-01

    Focal epithelial hyperplasia or Heck's disease is a rare contagious disease caused by human papillomavirus types 13 or 32, initially described among Native American populations. This condition is characterized by the occurrence of multiple small papules or nodules in oral cavity, especially on labial and buccal mucosa and tongue. This report describes the diagnosis of focal epithelial hyperplasia in five Central Amazonian Indians who sought treatment at the Amazonas State Foundation of Tropical Medicine (FMT-AM), using clinical criteria, polymerase chain reaction (PCR) and DNA sequencing.

  16. Complications of female circumcision in Nigerian Igbos.

    PubMed

    Egwuatu, V E; Agugua, N E

    1981-11-01

    An analysis is made of 43 children and 15 adult female patients who presented with post-circumcision complications at the University of Nigeria Teaching Hospital, Enugu, between January 1973 and December 1980; 57 patients had been circumcised within 21 days of birth and one patient in the seventh month of her first pregnancy. Age of presentation varied with the severity of the symptoms: 21 children and 11 adults presented with varying degrees of labial occlusion, while 9 children and 4 adults had implantation dermoids. Urinary retention was the problem in 12 children and one adult.

  17. Two new species of Esthemopsis C. Felder & R. Felder, 1865 (Lepidoptera: Riodinidae: Symmachiini) from southeastern and northeastern Brazil, with taxonomic comments on Esthemopsis teras (Stichel, 1910) stat. rev. and Esthemopsis pallida Lathy, 1932 stat. nov.

    PubMed

    Silva Dias, Fernando Maia; Dolibaina, Diego Rodrigo; Mielke, Olaf Hermann Hendrik; Casagrande, Mirna Martins

    2014-03-27

    Two new species of Esthemopsis C. Felder & R. Felder, 1865 from southeastern and northeastern Brazil are described, Esthemopsis sateri sp. nov. and Esthemopsis diamantina sp. nov., and revised and new combinations are proposed for Esthemopsis teras (Stichel, 1910) stat. rev. and Esthemopsis pallida Lathy, 1932 stat. nov., respectively. Lectotypes are designated for Lepricornis teras Stichel, 1910 and Esthemopsis caerulea pallida Lathy, 1932. The habitus of male and female specimens of the species discussed are illustrated; male head and labial palpus pictures, male and female genitalia illustrations are provided.

  18. Tooth surface floss loss: unusual interproximal and lingual cervical lesions as a result of bizarre dental flossing.

    PubMed

    Gow, Alex M; Kelleher, Martin G

    2003-01-01

    There are many reported cases of cervical abrasion/erosion cavities in the literature with various theories offered in support of their pathogenesis. The vast majority of these cases involve the labial cervical regions of the affected teeth. This case report describes an unusual dental presentation of severe lingual cervical and interproximal lesions predominantly affecting the upper and lower anterior and premolar teeth. The differential diagnosis is presented, along with the likely cause of the lesions: in this case, a bizarre oral hygiene technique. The proposed treatment plan is outlined and the problems associated with restoring such cavities are highlighted.

  19. Anatomy and physiology of female sexual function and dysfunction: classification, evaluation and treatment options.

    PubMed

    Berman, J R; Adhikari, S P; Goldstein, I

    2000-07-01

    Female sexual dysfunction is a significant age-related, progressive and highly prevalent problem that affects a substantial number of women in the United States. The female sexual response cycle is initiated by neurotransmitter-mediated vascular and nonvascular smooth muscle relaxation resulting in increased pelvic blood flow, vaginal lubrication, and clitoral and labial engorgement. These mechanisms are mediated by a combination of neuromuscular and vasocongestive events. Physiological impairments that interfere with the normal female sexual response bring about complaints associated with diminished sexual arousal, libido, vaginal lubrication, genital sensation, and ability to achieve orgasm. Therapy aimed at restoring hormone levels as well as genital blood flow will be discussed.

  20. Necrotizing sialometaplasia of the palate. Ulcerative or necrotizing stage of leukokeratosis nicotina palati?

    PubMed

    Philipsen, H P; Petersen, J K; Simonsen, B H

    1976-12-01

    A typical case of the recently described tumor-suspect lesion, necrotizing sialometaplasia (NS) of the palate, in a 54-year old Caucasian male is presented. Results of complete blood- and urinanalysis including serum electrophoresis and labial salivary gland biopsy strongly pointed at a local etiologic factor. Previous statements that the disease represents a new entity are questioned. The present authors favor the idea that NS is the necrotizing (ulcerative) or terminal stage of leukokeratosis nicotina palati (nicotinic stomatitis). It is of particular importance that this lesion is not diagnosed as a malignancy, as it heals spontaneously and uneventfully.

  1. Oral cysticercosis: a clinical dilemma.

    PubMed

    Wanjari, Sangeeta Panjab; Patidar, Kalpana A; Parwani, Rajkumar N; Tekade, Satyajitraje A

    2013-04-10

    Cysticercosis is a potentially fatal parasitic disease caused by cysticercus cellulosae, the larval stage of Taenia solium. Oral cysticercosis is a rare entity and represents difficulty in clinical diagnosis. This article reports two cases of oral cysticercosis involving buccal and labial mucosa. Both the cases presented with solitary, nodular swelling that had been clinically diagnosed as a mucocele. Histopathology of excisional biopsy revealed it to be cysticercosis. Single, cystic nodular swelling of oral cavity may be the only evidence of cysticercosis and may present first to dentist. These cases emphasise the role of dentist and thorough histopathological examination in the early diagnosis of disease that can prevent potential systemic complication.

  2. Oral cysticercosis: a clinical dilemma

    PubMed Central

    Wanjari, Sangeeta Panjab; Patidar, Kalpana A; Parwani, Rajkumar N; Tekade, Satyajitraje A

    2013-01-01

    Cysticercosis is a potentially fatal parasitic disease caused by cysticercus cellulosae, the larval stage of Taenia solium. Oral cysticercosis is a rare entity and represents difficulty in clinical diagnosis. This article reports two cases of oral cysticercosis involving buccal and labial mucosa. Both the cases presented with solitary, nodular swelling that had been clinically diagnosed as a mucocele. Histopathology of excisional biopsy revealed it to be cysticercosis. Single, cystic nodular swelling of oral cavity may be the only evidence of cysticercosis and may present first to dentist. These cases emphasise the role of dentist and thorough histopathological examination in the early diagnosis of disease that can prevent potential systemic complication. PMID:23580668

  3. Prophylactic root resection and periapical grafting for anterior implant aethetics: an integration of tissue-reconstruction and tissue-preservation concepts.

    PubMed

    Kan, Joseph Y K; Rungcharassaeng, Kitichai

    2004-06-01

    The presence of active infections involving the labial bony plate of a failing maxillary anterior tooth presents a challenging situation for aesthetic implant replacement. Not only would the septic state of an abscess be detrimental for immediate implant placement and bone augmentation, but the accompanying bony destruction would also increase the likelihood and magnitude of gingival recession, making this a bioaesthetic challenge. This article describes a technique that integrates tissue-reconstruction and tissue-preservation concepts to achieve peri-implant tissue aesthetics as well as its clinical rationale.

  4. Vowel distortion in traumatic dysarthria: lip rounding versus tongue advancement.

    PubMed

    Ziegler, W; von Cramon, D

    1983-01-01

    Formant analysis of tense, high, German vowels was performed to the end of obtaining information about the role of insufficient lip rounding in distorted vowel production of 8 traumatic dysarthrics. A comparison was made between two allophones of /y/ in different consonantal contexts. Noticeable undershoot in lip rounding or protrusion proved to occur in a context of conflicting labial gestures. Where the articulatory realization of a CVC sequence required gross tongue movements, a lingual undershoot resulted as the prevailing deficit. No evidence for dyscoordinative defects was obtained from the results.

  5. An Analysis of the Frame-Content Theory in Babble of Nine-Month-Old Babies with Cleft Lip and Palate

    PubMed Central

    Stout, Gwendolyn; Hardin-Jones, Mary; Chapman, Kathy L.

    2011-01-01

    The aim of this study was to examine the consonant-vowel co-occurrence patterns predicted by the Frame-Content theory in 16 nine-month-old babies with unrepaired cleft palate (± cleft lip) and 16 age-matched non-cleft babies. Babble from these babies was phonetically transcribed and grouped according to the intrasyllabic predictions of the theory (labial-central, alveolar-front, and velar-back). Both groups demonstrated the three consonant-vowel co-occurrence patterns predicted by the Frame-Content theory. Other patterns not predicted by the Frame-Content theory emerged as strong patterns as well. PMID:21889772

  6. Unusual Case of a Talon Cusp on a Supernumerary Tooth in Association with a Mesiodens

    PubMed Central

    Babaji, Prashant; Sanadi, Firoza; Melkundi, Mahesh

    2010-01-01

    Talon cusp is an accessory cusp similar to a projection, extending from the cingulum or cemento-enamel junction to the incisal edge. It occurs on labial or palatal surfaces of primary or permanent anterior teeth in both arches. This accessory cusp can occur as an isolated entity or in association with other dental anomalies. Occurrence of a talon cusp on supernu-merary teeth is rare and uncommon. This paper reports an unusual case of a talon cusp on a supernumerary tooth in association with mesiodens. PMID:22991599

  7. Unusual case of a talon cusp on a supernumerary tooth in association with a mesiodens.

    PubMed

    Babaji, Prashant; Sanadi, Firoza; Melkundi, Mahesh

    2010-01-01

    Talon cusp is an accessory cusp similar to a projection, extending from the cingulum or cemento-enamel junction to the incisal edge. It occurs on labial or palatal surfaces of primary or permanent anterior teeth in both arches. This accessory cusp can occur as an isolated entity or in association with other dental anomalies. Occurrence of a talon cusp on supernu-merary teeth is rare and uncommon. This paper reports an unusual case of a talon cusp on a supernumerary tooth in association with mesiodens.

  8. De Novo Mutation in ABCC9 Causes Hypertrichosis Acromegaloid Facial Features Disorder.

    PubMed

    Afifi, Hanan H; Abdel-Hamid, Mohamed S; Eid, Maha M; Mostafa, Inas S; Abdel-Salam, Ghada M H

    2016-01-01

    A 13-year-old Egyptian girl with generalized hypertrichosis, gingival hyperplasia, coarse facial appearance, no cardiovascular or skeletal anomalies, keloid formation, and multiple labial frenula was referred to our clinic for counseling. Molecular analysis of the ABCC9 gene showed a de novo missense mutation located in exon 27, which has been described previously with Cantu syndrome. An overlap between Cantu syndrome, acromegaloid facial syndrome, and hypertrichosis acromegaloid facial features disorder is apparent at the phenotypic and molecular levels. The patient reported here gives further evidence that these syndromes are an expression of the ABCC9-related disorders, ranging from hypertrichosis and acromegaloid facies to the severe end of Cantu syndrome.

  9. Frenectomy for improvement of a problematic conventional maxillary complete denture in an elderly patient: a case report.

    PubMed

    Al Jabbari, Youssef S

    2011-12-01

    Maxillary labial and buccal frena are considered as normal anatomic structures in the oral cavity. However, they may exist intraorally as a thick broad fibrous attachment and/or become located near the crest of the residual ridge, thus interfering with proper denture border extension resulting in inferior denture stability, retention and overall patient satisfaction. This case report highlights the importance of clinical examination and treatment planning which may mandate preprosthetic surgery prior to fabrication of a new conventional complete denture. Adequate patient satisfaction with conventional complete dentures can be significantly increased after frenectomy.

  10. The free gingival graft combined with the frenectomy: a clinical review.

    PubMed

    Breault, L G; Fowler, E B; Moore, E A; Murray, D J

    1999-01-01

    Abnormal labial frena are capable of retracting gingival margins, creating diastemas, and limiting lip movement. When these frena are present, the traditional frenectomy alone generally is successful. However, when the frenulum is extensive, the possibility of coronal reformation exists. Several procedures have combined the frenectomy with either a lateral pedicle flap, free papilla graft, or free gingival (mucosal) graft taken from the palate. Three case reports demonstrate the continued efficacy of the traditional palatal free gingival graft when the patient has an extensive frenulum or an area of minimal esthetic concern is involved.

  11. Descriptions and biological notes on three unusual mantellid tadpoles (Amphibia: Anura: Mantellidae) from southeastern Madagascar

    USGS Publications Warehouse

    Altig, R.; McDiarmid, R.W.

    2006-01-01

    The morphologies of three unusual tadpoles from slow-flowing, sandy-bottomed, rain forest streams in southeastern Madagascar are described. The large oral apparatus of the tadpole of Boophis picturatus Glaw, Vences, Andreone, and Vallan, 2001 lacks all keratinized structures and has an elaborately-folded lower labium with five, radially oriented, flattopped ridges. The tadpole of Mantidactylus guttulatus (Boulenger, 1881) lacks all keratinized mouthparts and has three immense papillae where the upper jaw normally occurs. The tadpole of Mantidactylus lugubris (Dumeril, 1853) has an ornate oral apparatus involving greatly hypertrophied derivatives of jaw serrations and unique structures on the lower labium that resemble labial teeth.

  12. Data set for Tifinagh handwriting character recognition.

    PubMed

    Bencharef, Omar; Chihab, Younes; Mousaid, Nouredine; Oujaoura, Mustapha

    2015-09-01

    The Tifinagh alphabet-IRCAM is the official alphabet of the Amazigh language widely used in North Africa [1]. It includes thirty-one basic letter and two letters each composed of a base letter followed by the sign of labialization. Normalized only in 2003 (Unicode) [2], ICRAM-Tifinagh is a young character repertoire. Which needs more work on all levels. In this context we propose a data set for handwritten Tifinagh characters composed of 1376 image; 43 Image For Each character. The dataset can be used to train a Tifinagh character recognition system, or to extract the meaning characteristics of each character.

  13. Buccal and palatal talon cusps with pulp extensions on a supernumerary primary tooth.

    PubMed

    Siraci, E; Cem Gungor, H; Taner, B; Cehreli, Z C

    2006-11-01

    This paper reports an unusual occurrence of talon cusp on a supernumerary primary incisor, presenting on both labial and palatal sides. The tooth was scheduled for extraction due to its interference with the occlusion. Morphometric analysis of the taloned cusps was performed on digitized replicas of the tooth crown using open-source image analysis toolkit (ImageJ). Further non-destructive investigation of the taloned crown under cone-beam X-ray computed tomography revealed pulpal extensions in both talon cusps.

  14. Interdisciplinary approach for the management of bilaterally impacted maxillary canines

    PubMed Central

    Sukh, Ram; Singh, Gyan P.; Tandon, Pradeep

    2014-01-01

    Interdisciplinary approach for the management of malocclusion provides a holistic approach of patient management. Prudent treatment planning is necessary to achieve the various treatment goals. This case report describes the orthodontic management of a 16-year-old adolescent female patient with bilateral labially impacted maxillary canines. The problems associated with impacted maxillary canines and the biomechanical interventions used for this patient are discussed. The treatment protocol involved surgical intervention, followed by sequential traction of the impacted teeth. An interdisciplinary approach to treatment with different mechanical strategies led to the achievement of the desired esthetic, functional, and occlusal treatment goals. PMID:25395776

  15. Rugonema labiatum n. g., n. sp. (Nematoda: Strongyloidea) from the stomach of Macropus irma (Marsupialia: Macropodidae) from Western Australia.

    PubMed

    Beveridge, I

    1999-11-01

    Rugonema labiatum n. g., n. sp. is described from the stomach of Macropus irma (Jourdan) from Western Australia. The new genus possesses four branches to the dorsal ray, has a cylindrical buccal capsule and lacks a cervical groove, placing it within the subfamily Cloacininae Stossich, 1899. The presence of a prominently striated buccal capsule and labial as well as cephalic collars places the genus within the tribe Pharyngostrongylinea Popova, 1952, but it is distinguished from all existing genera within the tribe by the possession of four lips. The presence of lips is an important characteristic of the related tribe Zoniolaiminea (Popova, 1952) and the characters used in distinguishing these two tribes are discussed.

  16. Contributions to the tooth morphology in early embryos of three species of hammerhead sharks (Elasmobranchii: Sphyrnidae) and their evolutionary implications.

    PubMed

    Mello, Waldiney; Brito, Paulo Marques Machado

    2013-09-01

    The tooth types in the embryos of the hammerhead sharks Sphyrna tiburo, Sphyrna tudes and Eusphyra blochii are here described in labial and lingual views, and, in some cases, in additional views. The presence of cusplets was observed in the anterior teeth of S. tiburo and S. tudes, which is secondarily lost after early embryonic stages. Many aligned root foramina were detected in the sphyrnids, which, as the cusplets, are shared by many phylogenetic-related carcharhinids. Other anatomic features, related to the root and central cusp, are presented for the first time. Such characters represent the first step to compare the teeth of extant and fossil species.

  17. ANKYLOGLOSSIA AND ITS INFLUENCE ON GROWTH AND DEVELOPMENT OF THE STOMATOGNATHIC SYSTEM

    PubMed Central

    Pompéia, Livia Eisler; Ilinsky, Roberta Simoni; Ortolani, Cristina Lúcia Feijó; Faltin, Kurt

    2017-01-01

    ABSTRACT Objective: To critically examine the existing Brazilian and International scientific literature regarding the influence of short lingual frenulum over growth and development of the stomatognathic system, as well as how it impacts the achievement of the shape-function balance. Data sources: An electronic literature search was conducted in databases, including MEDLINE/PubMed, Google Scholar, LILACS, SciELO, and ScienceDirect, using the key words “lingual frenum” and “development”, as well as their equivalents in Brazilian Portuguese. The literature search yielded 51 papers published between January 1997 and the present date; 14 articles of clinical trials were selected for meeting the inclusion criteria and were read in full. Data synthesis: The integrated literature review supported the proposition that some malocclusions are closely related to the presence of ankyloglossia and, although very few clinical trials on this topic have been published so far, there is a consensus among authors concerning the negative effects of functional imbalances over the stomatognathic system’s proper growth and development. Half of the studies found state that surgical interventions for releasing the lingual frenum are both safe and effective, concerning improvement in breastfeeding scores. Moreover, 4 out of the 14 studies included in this integrated review, report a negative influence of ankyloglossia over the orofacial muscular system. Conclusions: There is a consensus among the authors concerning the negative effects of lingual frenulum’s anatomic and functional alterations over craniofacial growth and development. The opinion about the early surgical intervention, however, is not unanimous.

  18. Oral and dental signs of child abuse and neglect

    PubMed Central

    COSTACURTA, M.; BENAVOLI, D.; ARCUDI, G.; DOCIMO, R.

    2015-01-01

    SUMMARY Aim The aim of this report is to identify the main oral and dental aspects of physical and sexual abuse and dental neglect in childhood, contributing to the precocious identification and diagnosis in a dental practice. Methods The oral and dental manifestations were divided and classified according to the type of child abuse: physical abuse, sexual abuse, neglect. Physical abuse Several studies in the literature have shown that oral or facial trauma occurs in about 50% of physically abused children; the oral cavity may be a central focus for physical abuse. Oro-facial manifestations of physical abuse include bruising, abrasions or lacerations of tongue, lips, oral mucosa, hard and soft palate, gingiva, alveolar mucosa, frenum; dental fractures, dental dislocations, dental avulsions; maxilla and mandible fractures. Sexual abuse Although the oral cavity is a frequent site of sexual abuse in children, visible oral injuries or infections are rare. Some oral signs may represent significant indications of sexual abuse, as erythema, ulcer, vescicle with purulent drainage or pseudomembranus and condylomatous lesions of lips, tongue, palate and nose-pharynx. Furthermore, if present erythema and petechiae, of unknown etiology, found on soft and hard palates junction or on the floor of the mouth, can be certainly evident proofs of forced oral sex. Dental neglect Oral signs of neglect are easily identifiable and are: poor oral hygiene, halitosis, Early Childhood Caries (ECC), odontogenous infections (recurrent and previous abscesses), periodontal disease, aptha lesions as a consequence of a nutritional deficiency status. Moreover, it is analyzed the assessment of bite marks because often associated with child abuse, the identification and collection of clinical evidence of this type of injury. Conclusion A precocious diagnosis of child abuse, in a dental practice, could considerably contribute in the identification of violence cases and in an early intervention. PMID

  19. Multidisciplinary management of ankyloglossia in childhood. Treatment of 101 cases. A protocol

    PubMed Central

    Pastor-Vera, Tomasa; Ferrés-Amat, Eduard; Mareque-Bueno, Javier; Prats-Armengol, Jordi; Ferrés-Padró, Eduard

    2016-01-01

    Background Partial ankyloglossia is a limitation which restricts the possibility of protrusion and elevation of the tip of the tongue due to the shortness of either the lingual frenulum or the genioglossus muscles or both. The principal objective of this paper is to present our protocol of action for the treatment of ankyloglossia. The specific objectives are to study patients with ankyloglossia treated by the Service of Maxillofacial Surgery and the Service of Speech Therapy of our pediatric Hospital, describe the diagnostic procedures, the pre-surgical intervention, the surgical technique undertaken and the post-surgical rehabilitation taking into account the level of collaboration of the patients, and finally, describe the surgical complications and the referral of patients. Material and Methods This is a descriptive study of healthy patients, without any diagnosis of syndrome, ranging between 4 and 14 years that have been surgically treated and rehabilitated post-surgery within a period of 2 years. Results 101 frenectomies and lingual plasties have been performed and patients have been treated following the protocol of action that we hereby present. After the surgical intervention, the degree of ankyloglossia has been improved, considering correction in 29 (28%) of the patients (95% CI: 20%, 38%), reaching, with the post-surgical orofacial rehabilitation, a correction of 97 (96%) of the participants (95% CI: 90%, 98%). Conclusions The chosen surgical technique for moderate-severe ankyloglossia in our centre is the frenectomy and lingual plasty. The myofunctional training begins one week before the surgical intervention so that the patients learn the exercises without pain. Key words:Ankyloglossia, tongue-tie, lingual frenum. PMID:26595832

  20. A Study on the Genetic Inheritance of Ankyloglossia Based on Pedigree Analysis

    PubMed Central

    Han, Soo-Hyung; Choi, Yun-Seok; Lim, Jin-Soo; Han, Ki-Taik

    2012-01-01

    Background Ankyloglossia or tongue-tie is a congenital anomaly characterized by an abnormally short lingual frenum. Its prevalence in the newborn population is approximately 4%. Its mode of inheritance has been studied in some articles, but no conclusion has been established. Also, no relevant report has been published in Korea. This study was conducted to elucidate the genetic inheritance of ankyloglossia via pedigree analysis. Methods In this study, 149 patients with no other congenital anomaly who underwent frenuloplasty between March 2001 and March 2010 were studied. Pedigrees were made via pre- or post-operative history taking, and patients with uncertain histories were excluded. In the patient group that showed a hereditary nature, the male-to-female ratio, inheritance rate, and pattern of inheritance were investigated. Results One hundred (67.11%) of the patients were male and 49 (32.89%) were female (male-female ratio=2.04:1). Ninety-one (61.07%) patients reported no other relative with ankyloglossia, and 58 (38.93%) patients had a relative with this disease. The inheritance rate was 20.69% in the 58 cases with a hereditary nature. In the group with no family history of ankyloglossia, the male-female ratio was 3.79:1, which significantly differed from that of the group with a family history of ankyloglossia. X-chromosome mediated inheritance and variation in the gene expression was revealed in the pedigree drawn for the groups with hereditary ankyloglossia. Conclusions Ankyloglossia has a significant hereditary nature. Our data suggest X-linked inheritance. This study with 149 patients, the first in Korea, showed X-linked inheritance in patients with a sole anomaly. PMID:22872835

  1. Phonetic specificity in early lexical acquisition: new evidence from consonants in coda positions.

    PubMed

    Nazzi, Thierry; Bertoncini, Josiane

    2009-01-01

    Use of precise consonantal information while learning new words has been established for onset consonants in previous studies, which showed that infants as young as 16 to 20 months of age can simultaneously learn two new words that differ only by a syllable-initial consonant (Havy & Nazzi, 2009; Nazzi, 2005; Nazzi & New, 2007; Werker, Fennell, Corcoran, & Stager, 2002). However, there is no systematic evidence to show whether specific phonetic information in other positions within the syllable can be used while learning new words. To the contrary, Nazzi (2005) found that when tested using the same task, 20-month-olds can learn two words that differ only by a consonant, but fail to do so if they differ only by a vowel, leaving open the possibility that specificity is limited to syllable-onset positions. Accordingly, the present study evaluated 20-month-olds' ability to learn two words that differ only by a consonant in either onset or coda position. Infants succeeded for both positions, ruling out the possibility that only syllable-onset positions are specified. This further suggests that the previously reported consonant/ vowel asymmetry cannot be fully explained by syllable-onset positional effects. Additionally, the present study evaluated whether words following a predominant labial-coronal pattern would be easier to learn than less frequent coronal-labial words. It failed to obtain any such evidence.

  2. A "bat" is easier to learn than a "tab": effects of relative phonotactic frequency on infant word learning.

    PubMed

    Gonzalez-Gomez, Nayeli; Poltrock, Silvana; Nazzi, Thierry

    2013-01-01

    Many studies have shown that during the first year of life infants start learning the prosodic, phonetic and phonotactic properties of their native language. In parallel, infants start associating sound sequences with semantic representations. However, the question of how these two processes interact remains largely unknown. The current study explores whether (and when) the relative phonotactic probability of a sound sequence in the native language has an impact on infants' word learning. We exploit the fact that Labial-Coronal (LC) words are more frequent than Coronal-Labial (CL) words in French, and that French-learning infants prefer LC over CL sequences at 10 months of age, to explore the possibility that LC structures might be learned more easily and thus at an earlier age than CL structures. Eye movements of French-learning 14- and 16-month-olds were recorded while they watched animated cartoons in a word learning task. The experiment involved four trials testing LC sequences and four trials testing CL sequences. Our data reveal that 16-month-olds were able to learn the LC and CL words, while14-month-olds were only able to learn the LC words, which are the words with the more frequent phonotactic pattern. The present results provide evidence that infants' knowledge of their native language phonotactic patterns influences their word learning: Words with a frequent phonotactic structure could be acquired at an earlier age than those with a lower probability. Developmental changes are discussed and integrated with previous findings.

  3. The tadpoles of two species of the Bokermannohyla circumdata group (Hylidae, Cophomantini).

    PubMed

    Pezzuti, Tiago Leite; Santos, Marcus Thadeu Teixeira; Martins, Sofia Velasquez; Leite, Felipe Sá Fortes; Garcia, Paulo Christiano Anchietta; Faivovich, Julián

    2015-11-25

    We describe the external morphology and oral cavity of the tadpoles of Bokermannohyla caramaschii and B. diamantina respectively from the states of Espírito Santo and Bahia, Brazil. Larvae of both species are distinguished from each other by external characters such as body shape, labial tooth-row formula, number of marginal papillae, coloration and internal oral anatomy features. Some of the character states of the tadpoles of B. caramaschii and B. diamantina that are shared with all other described tadpoles of the Bokermannohyla circumdata group, such as the absence/reduction of small flaps with accessory labial teeth laterally in the oral disc, and the absence/reduction of submarginal papillae, may represent morphological synapomorphies of this species group, or at least of some internal clade. The general pattern of brownish coloration with longitudinal stripes on the caudal muscle is also common to most species of the group. We did not find character states of the oral cavity that are exclusively shared by species of the B. circumdata group, or by other groups of Bokermannohyla.

  4. The efficiency of different light sources to polymerize resin cement beneath porcelain laminate veneers.

    PubMed

    Usumez, A; Ozturk, A N; Usumez, S; Ozturk, B

    2004-02-01

    Plasma arc light units for curing resin composites have been introduced with the claim of relatively short curing times. The purpose of this study was to evaluate the efficiency of two different light sources to polymerize dual curing resin cement beneath porcelain laminate veneers. Twenty extracted healthy human maxillary centrals were used. Teeth were sectioned 2 mm below the cemento-enamel junction and crown parts were embedded into self-cure acrylic resin, labial surface facing up. Cavity preparation was carried out on labial surfaces. These teeth were divided into two groups of 10 each. The resin cement/veneer combination was exposed to two different photo polymerization units. A conventional halogen light (Hilux 350, Express Dental Products) and a plasma arc light (Power PAC, ADT) were used to polymerize resin cement. Ten specimens were polymerized conventionally (40 s) and the other specimens by plasma arc curing (PAC) (6 s). Two samples from each tooth measuring 1.2 x 1.2 x 5 mm were prepared. These sections were subjected to microshear testing and failure values were recorded. Statistically significant differences were found between the bond strength of veneers exposed to conventional light and PAC unit (P < 0.001). Samples polymerized with halogen light showed better bond strength. The results of this study suggest that the curing efficiency of PAC through ceramic was lower compared with conventional polymerization for the exposure durations tested in this study.

  5. Study of MDM2 and SUMO-1 expression in actinic cheilitis and lip cancer.

    PubMed

    Oliveira Alves, Mônica Ghislaine; da Mota Delgado, Adriana; Balducci, Ivan; Carvalho, Yasmin Rodarte; Cavalcante, Ana Sueli Rodrigues; Almeida, Janete Dias

    2014-11-01

    Actinic cheilitis exhibits a potential of malignant transformation in 10-20 % of cases. The objective of this study was to compare the expression of MDM2 and SUMO-1 proteins between actinic cheilitis (AC) and squamous cell carcinoma (SCC) of the lip. The sample consisted of lower lip mucosa specimens obtained from cases with a clinical and histopathological diagnosis of AC (n = 26) and SCC (n = 25) and specimens of labial semi-mucosa (n = 15) without clinical alterations or inflammation. The tissue samples were stained with hematoxylin-eosin and anti-MDM2 and anti-SUMO-1 antibodies. Data were analyzed by the Kruskal-Wallis and Dunn's tests (5 %). The median expression of MDM2 (kW = 36.8565; df = 3-1 = 2; p = 0.0001) and SUMO-1 (kW = 32.7080; df = 3-1 = 2; p = 0.0001) was similar in cases of AC and SCC of the lip, but differed significantly from that observed for normal labial semi-mucosa. Despite the limitations of the present study, immunohistochemistry demonstrated the overexpression of important proteins (MDM2 and SUMO-1) related to regulatory mechanisms of apoptosis in AC and SCC of the lip, but further studies are needed.

  6. Investigation of vacuum forming techniques for reduction of loss in mouthguard thickness: part 2—effects of sheet grooving and thermal shrinkage.

    PubMed

    Takahashi, Mutsumi; Koide, Kaoru; Mizuhashi, Fumi; Sato, Toshihide

    2015-08-01

    The aim of this study was to investigate vacuum forming techniques for reduction of loss in mouthguard thickness effects of sheet grooving and thermal shrinkage of extruded sheets on molded mouthguard thickness. Mouthguards were fabricated with ethylene vinyl acetate (EVA) sheets (4.0 mm thick) using a vacuum forming machine. Sheet form was a convexing v-shaped groove toward the back, 10-40 mm from the anterior end. The sheets were placed in the forming machine with the sheet extrusion direction either vertical or parallel to the model's centerline of right and left. Molding was performed by crimping the sheet using suction when the most descending portion of the sheet sagged downwards from the clamp, 15 mm below the basal surface. Postmolding thickness was determined using a measuring device. Measurement points were the incisal portion (incisal edge and labial surface) and molar portion (cusp and buccal surface). Differences in molded mouthguard thickness with the sheet orientation of extruded EVA sheets were analyzed by student's t-test. The sheet in parallel axis orientation with the model's centerline yielded higher thickness than vertical orientation at the labial surface and the buccal surface. The present results suggested that addition of a groove to the sheet in conjunction with placement of the sheet with its axis of orientation parallel the centerline of the working model can effectively reduce thickness loss in the molded mouthguard with the equipment and materials used in this study.

  7. Comparative evaluation of soft and hard tissue dimensions in the anterior maxilla using radiovisiography and cone beam computed tomography: A pilot study

    PubMed Central

    Mallikarjun, Savita; Babu, Harsha Mysore; Das, Sreedevi; Neelakanti, Abhilash; Dawra, Charu; Shinde, Sachin Vaijnathrao

    2016-01-01

    Aims: To assess and compare the thickness of gingiva in the anterior maxilla using radiovisiography (RVG) and cone beam computed tomography (CBCT) and its correlation with the thickness of underlying alveolar bone. Settings and Design: This cross-sectional study included 10 male subjects in the age group of 20–45 years. Materials and Methods: After analyzing the width of keratinized gingiva of the maxillary right central incisor, the radiographic assessment was done using a modified technique for RVG and CBCT, to measure the thickness of both the labial gingiva and labial plate of alveolar bone at 4 predetermined locations along the length of the root in each case. Statistical Analysis Used: Statistical analysis was performed using Student's t-test and Pearson's correlation test, with the help of statistical software (SPSS V13). Results: No statistically significant differences were obtained in the measurement made using RVG and CBCT. The results of the present study also failed to reveal any significant correlation between the width of gingiva and the alveolar bone in the maxillary anterior region. Conclusions: Within the limitations of this study, it can be concluded that both CBCT and RVG can be used as valuable tools in the assessment of the soft and hard tissue dimensions. PMID:27143830

  8. Within- and across-language spectral and temporal variability of vowels in different phonetic and prosodic contexts: Russian and Japanese

    NASA Astrophysics Data System (ADS)

    Gilichinskaya, Yana D.; Hisagi, Miwako; Law, Franzo F.; Berkowitz, Shari; Ito, Kikuyo

    2005-04-01

    Contextual variability of vowels in three languages with large vowel inventories was examined previously. Here, variability of vowels in two languages with small inventories (Russian, Japanese) was explored. Vowels were produced by three female speakers of each language in four contexts: (Vba) disyllables and in 3-syllable nonsense words (gaC1VC2a) embedded within carrier sentences; contexts included bilabial stops (bVp) in normal rate sentences and alveolar stops (dVt) in both normal and rapid rate sentences. Dependent variables were syllable durations and formant frequencies at syllable midpoint. Results showed very little variation across consonant and rate conditions in formants for /i/ in both languages. Japanese short /u, o, a/ showed fronting (F2 increases) in alveolar context relative to labial context (1.3-2.0 Barks), which was more pronounced in rapid sentences. Fronting of Japanese long vowels was less pronounced (0.3 to 0.9 Barks). Japanese long/short vowel ratios varied with speaking style (syllables versus sentences) and speaking rate. All Russian vowels except /i/ were fronted in alveolar vs labial context (1.1-3.1 Barks) but showed little change in either spectrum or duration with speaking rate. Comparisons of these patterns of variability with American English, French and German vowel results will be discussed.

  9. Mucosal perforators from the facial artery.

    PubMed

    Coronel-Banda, Mauricio E; Serra-Renom, Jose M; Lorente, Marian; Larrea-Terán, Wendy P

    2014-07-01

    The cutaneous perforators of the facial artery have been well described, but to our knowledge the oral mucosal perforators have not. We studied 10 facial arteries from 10 hemifaces in 5 cadavers. The arteries were injected with latex, and we studied all perforators that extended from the facial artery and headed directly to the oral mucosa. The diameter and length of the facial artery and its mucosal perforators were measured and compared. We found 52 oral mucosal perforators in the 10 facial arteries injected with latex. Their mean (SD) diameter was 0.5 (0.2) mm and the mean (SD) number/facial artery was 5.2 (1.1). Their mean (SD) length was 16.4 (5.3) mm. Most of those to the cheek were localised between the branching-off points of the inferior and superior labial arteries. The facial artery has perforators to the oral mucosa of the cheek, most of them between the points at which the labial arteries emerge.

  10. The cephalic and pharyngeal sense organs of Calliphora vicina 3rd instar larvae are mechanosensitive but have no profound effect on ongoing feeding related motor patterns.

    PubMed

    Hückesfeld, Sebastian; Niederegger, Senta; Heinzel, H-G; Spiess, Roland

    2010-11-01

    The anterior segments of cyclorraphous Diptera larvae bear various sense organs: the dorsal- and terminal organ located on the cephalic lobes, the ventral- and labial organs associated with the mouthplate and the internal labral organ which lies on the dorsal surface of the esophagus. The sense organs are connected to the brain via the antennal nerve (dorsal- and labral organ) or the maxillary nerve (terminal-, ventral-, labial organ). Although their ultrastructure suggests also a mechanosensory function only their response to olfactory and gustatory stimuli has been investigated electrophysiologically. Here we stimulated the individual organs with step-, ramp-, and sinusoidal stimuli of different amplitude while extracellulary recording their afferents from the respective nerves. The external organs show a threshold of approximately 2 microm. All organs responded phasically and did not habituate to repetitive stimuli. The low threshold of the external organs combined with their rhythmically exposure to the substrate suggested a putative role in the temporal coordination of feeding. We therefore repetitively stimulated individual organs while simultaneously monitoring the centrally generated motor pattern for food ingestion. Neither the dorsal-, terminal- or ventral organ afferents had an obvious effect on the ongoing motor rhythm. Various reasons explaining these results are discussed.

  11. Ultramorphological characteristics of mature larvae of Nitidula carnaria (Schaller 1783) (Coleoptera: Nitidulidae), a beetle species of forensic importance.

    PubMed

    Ortloff, Alexander; Zanetti, Noelia; Centeno, Néstor; Silva, Ricardo; Bustamante, Felipe; Olave, Alvaro

    2014-06-01

    Beetles of the genus Nitidula Fabricius are forensically important, and their adults and larvae have been found associated with human corpses and animal carcasses in many places of the world. The external morphology of the larvae of Nitidula carnaria (Schaller 1783) was examined by scanning electron microscopy (SEM) to provide a description enabling identification of this forensically important species. The ultrastructure of the head was examined, antennae, mandibles, epipharynx, maxillary and labial palpi, spiracles, thorax, legs, and abdominal segments (especially segments 9 and 10); the tegument was also emphasised in this examination. Several types of sensilla were observed on the maxillary and labial palpi, including sensilla basiconica, sensilla styloconica, and perhaps a different type of sensilla digitiformia. In abdominal segment 10, a sensilla campaniformia was observed. Two types of plates were noticed in the abdominal tegument. The characteristics described here can be used to identify this species. No other study of the ultrastructure of Nitidulidae larvae is available for comparison. This is the first report of N. carnaria in carcasses in Chile.

  12. Marginal adaptation of Spinell InCeram and feldspathic porcelain laminate veneers

    PubMed Central

    Ghaffari, Tahereh; Hamedi-Rad, Fahimeh; Fakhrzadeh, Vahid

    2016-01-01

    Background: This in vitro study investigated the marginal fit of two porcelain laminate veneers to help the selection of more accurate veneers in discolored teeth. Materials and Methods: Thirty impressions of metal master die created from the prepared labial surface of an acrylic maxillary central incisor were made and poured with Type IV stone. The dies were distributed into test groups (n = 15) for the construction of DuCeram and InCeram laminate veneers. An image-analysis program was used to measure the gap between the veneers and the master die at the labial, lingual, and proximal margins. Statistical analysis was performed with repeated measures ANOVA. Independent t-test was used to compare the mean values between the two groups. Values of P < 0.05 were judged to be significant. Results: Differences between marginal fit of two groups were significant (P < 0.001). The overall mean marginal gap values (μm) for InCeram and DuCeram were, respectively, 114.4 ± 40.81 and 282.3 ± 82.82. Independent t-test revealed significant differences between the marginal gaps of two materials at different predetermined points. Conclusion: Within the limitations of this study, the marginal gap in InCeram laminate veneer was within the clinically acceptable standard set at 120 μm. PMID:27274344

  13. Influence of the coloring agent concentration on bleaching gel and pulp chamber temperatures during dental bleaching.

    PubMed

    Zamboni, Sandra Costa; Castanho, Gisela Muassab; Torres, Carlos Rocha Gomes; Nogueira, Lafayette; Borges, Alessandra B; Bottino, Marco Antonio

    2010-01-01

    This study evaluated the influence of the coloring agent concentration on the temperature of the gel layer and pulp chamber during dental bleaching with an LED/laser light source. Ten human incisors and a digital thermometer with K-type thermocouples were used. Using a high-speed spherical diamond bur, endodontic access was gained through openings on the lingual faces until pulp chamber was exposed. One end of the thermocouple was placed on the labial surface (immersed in bleaching gel) and the other end in the pulp chamber. The same 10 specimens were used in the 12 groups, according to the type and concentration of bleaching gel. Each bleaching gel was used in four different concentrations: manipulated without coloring, with normal quantity recommended by the manufacturer, with double the recommended amount of coloring, and with triple the recommended amount of coloring. The temperature rise was measured every 30 seconds for three minutes with a K-type thermocouple. The data were analyzed by ANOVA to examine the concentration and type of bleaching gel. This test was followed by Tukey's test, which was performed independently for the gel at the labial surface and the pulp chamber (a = 5%). For both surfaces, values of p = 0.00 were obtained for all factors and for the interaction between them. The varying concentrations of coloring agent produced statistically significant differences in terms of temperature increase for both the gel layer and the pulp chamber during activation.

  14. Surgical exposure of an impacted maxillary canine and increasing a band of keratinized gingiva.

    PubMed

    Vijayalakshmi, R; Ramakrishnan, T; Nisanth, S

    2009-09-01

    An adequate amount of keratinized gingival tissue that is under proper plaque control, is a fundamental requirement for periodontal health. When the teeth erupt uneventfully in the center of the alveolar ridge, an adequate amount of keratinized tissue will surround the erupted permanent tooth. Labially or buccally erupting teeth show reduced dimensions of the gingiva as abnormal eruption of permanent teeth restricts or eliminates the keratinized tissue between the erupting cusp and the deciduous tooth. A lack of attached gingiva poses a potential risk for gingival recession in labially or buccally erupted teeth due to the possibility of accumulation of plaque and/or traumatic tooth-brushing during subsequent orthodontic treatment. A good understanding between the orthodontist and periodontist along with proper management of periodontal tissues, can prevent these problems. Various surgical techniques can be employed to uncover impacted teeth. This paper discusses the validity of utilizing periodontal surgery to increase a band of keratinized tissue in a case of an impacted canine erupting from the alveolar mucosa.

  15. A comparative study of different bleaching agents on the morphology of human enamel: an in vitro SEM study.

    PubMed

    Uthappa, Roshan; Suprith, M L; Bhandary, Shreetha; Dash, Sumit

    2012-11-01

    The purpose of the study was to compare two different commercial bleaching agents, Opalescence with Colgate Platinum, and 30% phosphoric acid used as aggressive agent on the morphology of human enamel. Ten freshly extracted, noncarious, human maxillary central incisors extracted for periodontal reasons were used in this study. The labial surface of the disinfected teeth were polished using a polishing paste with the help of rubber cup and a slow speed handpiece. Each tooth was sectioned at cement-enamel junction and the crown was separated into four specimens, all taken from labial surface. Group 1 was treated with Colgate Platinum for 7 hours, group 2 with Opalescence for 7 hours, group 3 was treated with 30% phosphoric acid for 30 seconds and group 4 was untreated and used as control. After the treatment period, the specimens were washed with normal saline and stored in sterile bottle and sealed. Photomicrographs obtained from the scanning electron microscopy (SEM) after surface treatments were examined for no alteration, slight alteration, moderate alteration and severe alterations. The specimens treated with commercial bleaching agents revealed no enamel surface morphologic alterations compared to control group. The specimen treated with phosphoric acid showed severe alterations. Ten percent carbamide peroxide evaluated in this study does not etch tooth enamel or alter enamel surface morphology as do conventional etching techniques. Carbamine peroxide is a safe and effective tooth whitening agent even when used for extended period of time. The enamel surface remains smooth which reduces caries due to plaque collection.

  16. A new evaluation of heat distribution on facial skin surface by infrared thermography

    PubMed Central

    Brioschi, Marcos L; Baladi, Marina G; Arita, Emiko S

    2016-01-01

    Objective: The aim of this study was to identify the facial areas defined by thermal gradient, in individuals compatible with the pattern of normality, and to quantify and describe them anatomically. Methods: The sample consisted of 161 volunteers, of both genders, aged between 26 and 84 years (63 ± 15 years). Results: The results demonstrated that the thermal gradient areas suggested for the study were present in at least 95% of the thermograms evaluated and that there is significant difference in temperature between the genders, racial group and variables “odontalgia”, “dental prothesis” and “history of migraine” (p < 0.05). Moreover, there was no statistically significant difference in the absolute temperatures between ages, and right and left sides of the face, in individuals compatible with the pattern of normality (ΔT = 0.11°C). Conclusions: The authors concluded that according to the suggested areas of thermal gradients, these were present in at least 95% of all the thermograms evaluated, and the areas of high intensity found in the face were medial palpebral commissure, labial commissure, temporal, supratrochlear and external acoustic meatus, whereas the points of low intensity were inferior labial, lateral palpebral commissure and nasolabial. PMID:26891669

  17. Alveolar bone thickness and lower incisor position in skeletal Class I and Class II malocclusions assessed with cone-beam computed tomography

    PubMed Central

    Ucar, Faruk Izzet; Buyuk, Suleyman Kutalmis; Ozer, Torun; Uysal, Tancan

    2013-01-01

    Objective To evaluate lower incisor position and bony support between patients with Class II average- and high-angle malocclusions and compare with the patients presenting Class I malocclusions. Methods CBCT records of 79 patients were divided into 2 groups according to sagittal jaw relationships: Class I and II. Each group was further divided into average- and high-angle subgroups. Six angular and 6 linear measurements were performed. Independent samples t-test, Kruskal-Wallis, and Dunn post-hoc tests were performed for statistical comparisons. Results Labial alveolar bone thickness was significantly higher in Class I group compared to Class II group (p = 0.003). Lingual alveolar bone angle (p = 0.004), lower incisor protrusion (p = 0.007) and proclination (p = 0.046) were greatest in Class II average-angle patients. Spongious bone was thinner (p = 0.016) and root apex was closer to the labial cortex in high-angle subgroups when compared to the Class II average-angle subgroup (p = 0.004). Conclusions Mandibular anterior bony support and lower incisor position were different between average- and high-angle Class II patients. Clinicians should be aware that the range of lower incisor movement in high-angle Class II patients is limited compared to average- angle Class II patients. PMID:23814708

  18. Effect of laser phototherapy on recurring herpes labialis prevention: an in vivo study.

    PubMed

    de Carvalho, Renata Rodrigues; de Paula Eduardo, Fernanda; Ramalho, Karen Müller; Antunes, José Leopoldo Ferreira; Bezinelli, Letícia Mello; de Magalhães, Marina Helena Cury Gallottini; Pegoretti, Tatiana; de Freitas, Patrícia Moreira; de Paula Eduardo, Carlos

    2010-05-01

    Alternative treatment for recurrent labial infection by herpes simplex virus (HSV) have been considered. The aim of this study was to evaluate the effectiveness of laser phototherapy in prevention and reduction of severity of labial manifestations of herpes labialis virus. Seventy-one patients, divided into experimental (n = 41) and control (n = 30) groups were followed up for 16 months. Patients in the control group were treated topically with aciclovir and patients in the experimental group were subjected to laser phototherapy (one session per week, 10 weeks): 780 nm, 60 mW, 3.0 J/cm(2) or 4.5 J/cm(2) on healthy (no HSV-1 infection) and affected (with HSV-1 infection) tissues. Patients in the experimental group presented a significant decrease in dimension of herpes labialis lesions (P = 0.013) and inflammatory edema (P = 0.031). The reduction in pain level (P = 0.051) and monthly recurrences (P = 0.076) did not reach statistical significance. This study represents an in vivo indication that this treatment should be further considered as an effective alternative to therapeutic regimens for herpes labialis lesions.

  19. Functional morphology and sexual dimorphism of mouthparts of the short-faced scorpionfly Panorpodes kuandianensis (Mecoptera: Panorpodidae).

    PubMed

    Ma, Na; Huang, Jing; Hua, Baozhen

    2013-01-01

    Mouthparts are closely associated with the feeding behavior and feeding habits of insects. The features of mouthparts frequently provide important traits for evolutionary biologists and systematists. The short-faced scorpionflies (Panorpodidae) are distinctly different from other families of Mecoptera by their extremely short rostrum. However, their feeding habits are largely unknown so far. In this study, the mouthpart morphology of Panorpodes kuandianensis Zhong et al., 2011 was investigated using scanning electron microscopy and histological techniques. The mandibulate mouthparts are situated at the tip of the short rostrum. The clypeus and labrum are short and lack distinct demarcation between them. The epipharynx is furnished with sublateral and median sensilla patches. The blade-shaped mandibles are sclerotized and symmetrical, bearing apical teeth and serrate inner margins. The maxilla and labium retain the structures of the typical pattern of biting insects. The hirsute galea, triangular pyramid-shaped lacinia, and labial palps are described in detail at ultrastructural level for the first time. Abundant sensilla are distributed on the surface of maxillary and labial palps. The sexual dimorphism of mouthparts is found in Panorpodes for the first time, mainly exhibiting on the emargination of the labrum and apical teeth of mandibles. Based on the features of mouthparts, the potential feeding strategy and feeding mechanism are briefly discussed in Panorpodes.

  20. Four new species of free-living marine nematodes of the family Comesomatidae (Nematoda: Araeolaimida) from coast of Vietnam.

    PubMed

    Gagarin, Vladimir G

    2013-01-24

    Specimens of four new nematode species of the family Comesomatidae were isolated from the sediments of littoral zone of South China Sea at the coast of Vietnam and described and illustrated. Sabatieria curvispiculata sp. n. is characterized by the long and slender tail, short cephalic setae and strongly curved spicules in males. Setosabatiera orientalis sp. n. is close to S. australis Riera, Nunez, Brito, 2006, but differs from it in the comparatively shorter and more slender tail, small-er number of amphidial fovea turns, greater number of precloacal supplements in males and shape and structure of spic-ules. Dorylaimopsis intermedia sp. n. is morphologically closest to D. mediterranea Grimaldi-de Zio, 1968 and D. magellanense Chen, Vincx, 1968, but differs from both species in the longer outer labial setae and absence of precloacal supplements in males. D. brevispiculata sp. n. is similar to D. turneri Zhang, 1992 and D. coomansi Muthumbi, Soetaert, Vincx, 1977, but differs from both species in the shape of outer labial sensillae and absence of precloacal supplements in males. A pictorial key for determination of valid species in the genus Setosabatieria Rouville, 1903 is given.

  1. Vascular mapping of the face: B-mode and doppler ultrasonography study

    PubMed Central

    Tucunduva-Neto, Raul; Saieg, Mauro; Costa, Andre-Luiz; de Freitas, Cláudio

    2016-01-01

    Background To analyze the face vascularization pattern using B-mode and Doppler ultrasonography, and also propose an arterial vessel mapping. Material and Methods The investigation was performed on 20 ultrasonography exams of facial vessels through linear and endocavitary transducers. We analyzed and determined the average values for diameters, peak systolic velocity and resistive index of the following arteries: external carotid, lingual, deep lingual, sublingual, facial, submental, inferior labial, superior labial, angular, maxillary inferior alveolar, mental, buccal, greater palatine, infraorbital, superficial temporal, transverse facial and frontal. Results Data was obtained allowing the analysis of the tissue hemodynamics. We were able to map the vascularization of the face and it was possible to access three arteries of small diameter (0,60mm angular artery; 0,55mm greater palatine artery; 0,45mm infraorbital artery). Conclusions The results presented in this article are valid tool supporting the non-invasive mapping of facial vascularization. Key words:Anatomy, vascularization, ultrasonography, doppler. PMID:26827055

  2. Consonant-vowel co-occurrence patterns in Mandarin-learning infants.

    PubMed

    Chen, Li-Mei; Kent, Raymond D

    2005-08-01

    Most studies on CV co-occurrence patterns in early phonetic development have been based on Indo-European languages. Data from infants learning Mandarin, which has a substantially different phonological system from Indo-European languages, can confirm or refute the findings of previous studies, thus shedding further light on the theoretical bases of CV association. Spontaneous vocalizations were recorded in 45-minute sessions for each of 24 Mandarin-learning infants aged 0;7 to 1;6. In addition, the speech production of 24 caregivers was audio-recorded during their natural daily interactions with the infants at home. Both infants' vocalizations and adults' speech were transcribed and analysed for consonant-vowel co-occurrence patterns. These patterns were similar to those in other language groups, but language-specific patterns were evident by 1;0. Combinations of alveolars+front vowels and velars+back vowels confirm Davis & MacNeilage's (1990, 1995) frame-then-content theory and Clements's (1991) model of unified features for consonants and vowels. However, our finding of a language-specific pattern (labials+back vowels) suggests the need to reexamine the 'pure frame' of Davis & MacNeilage and Clements's grouping of labials and rounded vowels.

  3. Structural and functional comparison of the proboscis between tapirs and other extant and extinct vertebrates.

    PubMed

    Milewski, Antoni V; Dierenfeld, Ellen S

    2013-03-01

    Tapirs (Perissodactyla: Tapiridae) are the only living vertebrates, beyond the order Proboscidea, found to possess a true proboscis, defined as a flexible tubular extension of the joint narial and upper labial musculature that serves, at least in part, to grasp food. Tapirs show only partial homology and analogy with elephants in the narial and upper labial structures, as well as in the skull bones and teeth. However, superficially similar extensions in other extant vertebrates differ greatly in anatomy and function. Therefore, they deserve new names: prorhiscis (e.g. Mammalia: Saiga tatarica), prorhinosis (e.g. Chondrichthyes: Callorhinchus spp.), prorhynchis (e.g. Osteichthyes: Campylomormyrus spp.) and progeneiontis (e.g. Osteichthyes: Gnathonemus spp.). Among non-mammalian vertebrates, no bird or reptile is known to possess a proboscis. Among fishes, there are various extensions of the rostrum, jaws, 'nose' and 'chin' that lack the required narial involvement. The skulls of extinct mammals within (e.g. deinotheres) and beyond (e.g. astrapotheres) the Proboscidea confirm that a proboscis evolved independently in several mammalian lineages before the Pliocene. This convergence with tapirs presumably reflects, in part, the advantages of concentrating the olfactory sensor on what is, effectively, the tip of a long mobile upper lip. However, the proboscis does not appear to have arisen de novo in any vertebrate post-Pliocene, and its continued evolution has apparently depended on the further development of its length, flexibility and innervations, as epitomized by elephants.

  4. Shear bond strength evaluation of adhesive and tooth preparation combinations used in reattachment of fractured teeth: an ex-vivo study.

    PubMed

    VamsiKrishna, Ramachandruni; Madhusudhana, Koppolu; Swaroopkumarreddy, Aluru; Lavanya, Anumula; Suneelkumar, Chinni; Kiranmayi, Govula

    2015-01-01

    The objectives of this study were to evaluate the bond strengths of different adhesive materials, different tooth preparation designs and adhesive tooth preparation combinations to reattach fractured incisor fragments. The study sample comprised 48 intact human maxillary central incisors divided into two groups A and B. The incisal third was sectioned with a diamond disc. The teeth in Group A were reattached with bonding agent and in Group B with resin luting cement. The teeth in each Group were further divided into three sub-groups based on the preparation designs viz., simple attachment, chamfer on labial surface, groove with shoulder on labial surface and restored with nano-composite. Shear Bond Strength was calculated by applying load incisal to the fracture line. T-test and one-way ANOVA were used to evaluate the bond strength between the groups and within the group respectively. Reattachment with resin luting cement showed high bond strength compared to bonding agent (P < 0.05). Within the subgroups 'groove with shoulder' showed better bond strength compared to simple attachment and chamfer and the result was statistically significant (P < 0.05). Reattachment of fractured fragments can be considered as a good alternative treatment option when the fragment is available.Reattachment with resin luting cement and the preparation design of "groove with shoulder" showed better results.

  5. Anti-HIV antibody in saliva: an assessment of the role of the components of saliva, testing methodologies and collection systems.

    PubMed

    Lamey, P J; Nolan, A; Follett, E A; Coote, I; MacFarlane, T W; Kennedy, D H; Connell, A; Parry, J V

    1996-03-01

    The various components of saliva, namely mixed saliva, parotid saliva, submandibular saliva, crevicular fluid and minor (labial) gland secretions, were collected from 63 known HIV antibody seropositive patients. A commercial test system, Wellcozyme HIV 1+2, and an antibody capture ELISA (GACELISA), were compared for sensitivity against all components. Sensitivity of the GACELISA system was 100% in 123 mixed saliva, 121 parotid saliva and 127 labial fluid samples, and 98% in 99 submandibular samples and 127 crevicular fluid samples. Respective figures for Wellcozyme 1+2 were 92%, 55%, 73%, 66% and 63%. Mixed saliva was most easily, conveniently and effectively collected using a plain Salivette. In 241 Salivette samples examined from the 63 patients, GACELISA proved 100% sensitive, and Wellcozyme 95% sensitive. Another form of Salivette impregnated with citric acid was unsuitable for GACELISA and gave a false negative value of 45%. In 197 samples from the gingival margin taken by a dry swab, GACELISA showed a sensitivity of 98% and Wellcozyme 81%. The most sensitive method for demonstrating anti-HIV antibody in saliva is to collect mixed saliva with the plain Salivette system and assay anti-HIV antibody levels by GACELISA.

  6. Vergisson 4: a left-handed Neandertal.

    PubMed

    Condemi, Silvana; Monge, Janet; Quertelet, Sylvain; Frayer, David W; Combier, Jean

    2017-01-01

    Handedness is an important marker for lateralization of humans in the modern and fossil record. For the most part, Neandertals and their ancestors are strongly right-handed. We describe a single tooth from a Neandertal level at Vergisson 4 (Vg 4-83). This left upper central incisor shows all the features typical of Neandertal incisors. It also exhibits a predominance of left-handed striations. Striations on the incisor's labial surface were mapped at 20x magnification using Photoshop. Angulations of the striations were determined from their deviation from the maximum mesio-distal line and were analyzed using NIH's freeware, Image J. Of the 60 labial surface striations, Vg 4-83 shows a strong predominance of left-handed striations (46; 76.7%), which are statistically significantly different (p < .001 with a two-tailed chi(2) test) from the small number (3) of right-handed striations. The identification of another left-handed Neandertal adds to our understanding about handedness variation in this fossil hominin. Given the high frequency of right-handed Neandertals, the 90: 10 modern ratio is still preserved in this group. © 2016 Wiley Periodicals, Inc.

  7. The Effect of Changes in Lower Incisor Inclination on Gingival Recession

    PubMed Central

    Kamak, Gulen; Kamak, Hasan; Keklik, Hakan; Gurel, Hakan Gurcan

    2015-01-01

    Aim. Orthodontic treatment may promote development of recessions. The mechanism by which orthodontic treatment influences occurrence of recessions remains unclear. The aim of this study was to test the hypothesis that a change of mandibular incisor inclination promotes development of labial gingival recessions. Materials and Methods. The study sample comprised dental casts and lateral cephalograms obtained from 109 subjects before orthodontic treatment (Tb) and after orthodontic treatment (Ta). Depending on the change of lower incisor inclination during treatment, the subjects were divided into three groups: Retroclination (R), Stable Position (S), and Proclination (P). The presence of gingival recessions of mandibular incisors and clinical crown heights were assessed on plaster models. Results and Conclusions. From Tb to Ta, Inc_Incl showed a statistically significant change in the R, P, and S groups (p < 0.05). Increase of clinical crown heights of the lower incisors (42, 4, and 31) was not statistically significant in any group. The only statistically significant intergroup difference was the greater increase of the clinical crown height of tooth number 32 in the P group in comparison with the R group (p = 0.049). The change of lower incisor inclination during treatment did not lead to development of labial gingival recessions in the study sample. PMID:25961071

  8. Relationship of occlusion and periodontal disease: part IX-incisor inclination and periodontal status.

    PubMed

    Geiger, A M; Wasserman, B H

    1976-04-01

    In this study population the following observations have been made: Periodontal destruction, gingival inflammation and mobility were not significantly related to axial inclination of the incisor teeth. Labial gingival recession of the mandibular incisor was related to linguoversion (less than 85 degrees to GoGn). No other associations between incisor inclination and labial or lingual recession were found. Age was not related to either maxillary or mandibular incisor inclination. The periodontal-incisor inclination relationships reported above for periodontal destruction and gingival inflammation were not altered by the factor of age. Study of the secondary influence of incisor inclination on the relationships of selected occlusal factors and periodontal pathosis showed: A. Severe overjet (more than 6mm) had been found to be associated with more periodontal destruction. With severe overjet maxillary incisors in linguoversion (less than 100 degrees to SN) were somewhat healthier than all others. Among the same cases of severe overjet mandibular incisors in labioversion had slightly more disease than all others. B. The absence of a significant correlation between anterior overbite or crowding reported previously was not influenced by incisor inclination. C. Facial alveolar bone thickness, observed clinically, was studied for its relation to periodontal destruction and gingival inflammation. Thick facial alveolar bone was found to be associated with increased pathosis. This finding was not consistent for the maxillary and mandibular incisor and the influence of other factors might be suspected: Incisor inclination had no effect on the bone thickness-periodontal disease findings.

  9. Place assimilation across words in running speech: corpus analysis and perception.

    PubMed

    Zimmerer, Frank; Reetz, Henning; Lahiri, Aditi

    2009-04-01

    Place assimilation can lead to neutralization of segmental contrasts. It is controversial, however, to what extent such neutralizations actually happen in natural speech. This study examines: (i) the degree to which regressive place assimilations occur in word final consonants in conversational German, and (ii) whether these assimilations are perceived as neutralized by listeners. The production analysis, based on spontaneous speech, shows that complete assimilations do take place in conversational speech and that there is a clear asymmetry between coronal versus labial and dorsal segments. Furthermore, function words show a higher degree of assimilation than lexical words. Two experiments examined the effects of assimilation on perception. A forced choice reaction time perception experiment, using nasal stimuli from the corpus, examined how fast and accurately listeners identified sounds in different segmental contexts. Results indicate that (a) with equal accuracy and speed, listeners identified original and assimilated [m]s; (b) unassimilated-/m/s were identified equally well across contexts, but not unassimilated-/n/s. A free transcription experiment reproduced these findings. An acoustic analysis provides further evidence that regressive place assimilation across word boundaries can result in absolute neutralization of place contrasts in running speech. The results support models predicting asymmetries between coronal versus labial and dorsal consonants.

  10. Facial surface changes after cleft alveolar bone grafting.

    PubMed

    Krimmel, Michael; Schuck, Nils; Bacher, Margit; Reinert, Siegmar

    2011-01-01

    The aim of this study was to assess the 3-dimensional facial surface changes after cleft alveolar bone grafting with digital surface photogrammetry. In a prospective study, 22 patients with cleft lip and palate underwent alveolar bone grafting. Before the procedure and 6 weeks postoperatively and before the continuation of orthodontic treatment, 3-dimensional images were taken with digital surface photogrammetry. Seven standard craniofacial landmarks on the nose and the upper lip were identified. Their spatial change because of bone grafting was assessed. Statistical analysis was performed with analysis of variance and t test. A significant increase in anterior projection on the operative side (P < .05) was found for the labial insertion points of the alar base (subalare). No significant changes were detected for the position of the labial landmarks. Our results show 3-dimensionally that there is a positive influence of the alveolar bone graft on the projection of the alar base on the cleft side. Copyright © 2011 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  11. Upper incisors' positions after extraction.

    PubMed

    Werneck, Eduardo César; Mattos, Fernanda Silva; Cotrim-Ferreira, Flávio Augusto; Prado, Renata Falchete; Silva, Márcio Garcia; Araújo, Adriano Marotta

    2014-01-01

    The aim of this research was to verify the amount of horizontal and vertical movement and incisor inclination of upper incisors and correlate these with Edgewise and Alexander brackets use and the presence of overbite during anterior retraction in sliding mechanics. The sample was composed of 40 adult patients divided into 2 groups, treated with Edgewise and Alexander brackets (20 each) subdivided in 2 groups (10 each), according to the presence or absence of deep bite. Treatment consisted of 4 extraction cases with sliding mechanics with the 2 different brackets. Pre- and post-treatment cephalograms were measured and the values of interest submitted to descriptive statistical analysis, ANOVA at 5%, the Tukey test and Pearson's correlation. Upper incisor retraction was not related to the brackets used nor to the presence of deep bite, though lingual tipping was greater when Edgewise brackets were used and deep bite was absent. No statistically significant differences in upper incisor vertical movements were observed and no correlation was determined between upper incisor intrusion and lower incisor labial tipping in overbite correction or in upper incisor retraction and lower incisor labial tipping for overjet correction. Bracket prescription and its interaction with deep bite were significant and Edgewise brackets without deep bite showed the worst inclination control. It was concluded that bracket prescriptions are important to increase control of sliding mechanics.

  12. Influence of dietary nutritional composition on caterpillar salivary enzyme activity.

    PubMed

    Babic, Branislav; Poisson, Alexandre; Darwish, Shireef; Lacasse, Jean; Merkx-Jacques, Magali; Despland, Emma; Bede, Jacqueline C

    2008-01-01

    Caterpillars are faced with nutritional challenges when feeding on plants. In addition to harmful secondary metabolites and protein- and water-limitations, tissues may be carbohydrate-rich which may attenuate optimal caterpillar performance. Therefore, caterpillars have multiple strategies to cope with surplus carbohydrates. In this study, we raise the possibility of a pre-ingestive mechanism to metabolically deal with excess dietary sugars. Many Noctuid caterpillars secrete the labial salivary enzyme glucose oxidase (GOX), which oxidizes glucose to hydrogen peroxide and gluconate, a nutritionally unavailable carbohydrate to the insect. Beet armyworm, Spodoptera exigua, larvae were restricted to diets varying in protein to digestible carbohydrate (P:C) ratio (42p:21c; 33p:30c; 21p:42c) and total nutrient concentration (42% and 63%). High mortality and longer developmental time were observed when caterpillars were reared on the C-biased, P-poor diet (21p:42c). As the carbohydrate content of the diet increased, caterpillars egested excess glucose and a diet-dependent difference in assimilated carbohydrates and pupal biomass was not observed, even though caterpillars restricted to the C-biased diet (21p:42c) accumulated greater pupal lipid reserves. Larval labial salivary GOX activity was also diet-dependent and gluconate, the product of GOX activity, was detected in the frass. Unexpectedly, GOX activity was strongly and positively correlated with dietary protein content.

  13. A new evaluation of heat distribution on facial skin surface by infrared thermography.

    PubMed

    Haddad, Denise S; Brioschi, Marcos L; Baladi, Marina G; Arita, Emiko S

    2016-01-01

    The aim of this study was to identify the facial areas defined by thermal gradient, in individuals compatible with the pattern of normality, and to quantify and describe them anatomically. The sample consisted of 161 volunteers, of both genders, aged between 26 and 84 years (63 ± 15 years). The results demonstrated that the thermal gradient areas suggested for the study were present in at least 95% of the thermograms evaluated and that there is significant difference in temperature between the genders, racial group and variables "odontalgia", "dental prothesis" and "history of migraine" (p < 0.05). Moreover, there was no statistically significant difference in the absolute temperatures between ages, and right and left sides of the face, in individuals compatible with the pattern of normality (ΔT = 0.11°C). The authors concluded that according to the suggested areas of thermal gradients, these were present in at least 95% of all the thermograms evaluated, and the areas of high intensity found in the face were medial palpebral commissure, labial commissure, temporal, supratrochlear and external acoustic meatus, whereas the points of low intensity were inferior labial, lateral palpebral commissure and nasolabial.

  14. Augmented corticotomy-assisted presurgical orthodontics of class III malocclusions: a cephalometric and cone-beam computed tomography study.

    PubMed

    Wang, Bo; Shen, Guofang; Fang, Bing; Yu, Hongbo; Wu, Yong

    2013-11-01

    The purpose of this study was to evaluate mandibular incisor decompensation and the surrounding periodontal status with augmented corticotomy-assisted presurgical orthodontics of class III patients. Fifty-six surgical class III patients were enrolled in this study, 26 of whom chose augmented corticotomy-assisted presurgical orthodontics (G1), and 30 chose conventional procedures (G2). Cone-beam computed tomography images and lateral cephalograms were obtained from each patient before and after presurgical orthodontics. Measurements of variables were compared using Student t tests and separate variance estimation t tests. The amount of mandibular incisor decompensation and the increase in labial alveolar bone thickness in G1 were greater than those in G2 during presurgical orthodontics (P < 0.001), however, root resorption (P < 0.001), the decrease in lingual alveolar bone thickness (P < 0.001), and vertical alveolar bone loss on both labial (P < 0.05) and lingual sides (P < 0.001) were less in G1 than in G2. Sufficient mandibular incisor decompensation and better periodontal preservation were achieved with augmented corticotomy-assisted presurgical orthodontics for class III patients compared with traditional procedures.

  15. The effect of an anterior biteplate on dental and skeletal Class II correction using headgears: a cephalometric study.

    PubMed

    Thurman, M M; King, G J; Ramsay, D S; Wheeler, T T; Phillips, C

    2011-11-01

    To test the hypothesis that there are significant differences in skeletal and/or dental changes between Class II subjects treated with headgear (HG) compared with those treated with HG plus maxillary acrylic biteplate (BP) discluding teeth. Secondary analysis performed in Department of Orthodontics at the University of Washington. Fifty pre-adolescent Class II subjects were treated with HG as part of a randomized clinical trial (RCT) at the University of North Carolina/Chapel Hill, and 81 similar subjects were treated with HG plus a flatplane maxillary anterior BP for occlusal separation and anterior labial bow at the University of Florida as part of a separate RCT. This retrospective cohort study examined anteroposterior (AP) and vertical cephalometric changes in two cohorts of Class II subjects. Pre- and post-treatment cephalometric radiographs for each group were obtained from the two centers and measured for dental and skeletal changes. These data were adjusted for differences in magnification and compared using ancova, controlling for important cohort and protocol differences between the two centers. Overbite and maxillary incisor inclinations were reduced significantly more in the HG/BP group. All other vertical and AP changes were not statistically significantly different between the groups. The maxillary anterior BP with labial bow is an effective appliance for reducing overbite and retracting incisors but provides no additional AP dental or skeletal benefit over HG treatment. © 2011 John Wiley & Sons A/S.

  16. Treatment effects of the Forsus Fatigue Resistant Device used with miniscrew anchorage.

    PubMed

    Aslan, Belma I; Kucukkaraca, Ebru; Turkoz, Cagri; Dincer, Mufide

    2014-01-01

    To evaluate the dentofacial effects of the Forsus Fatigue Resistant Device (FRD) used with miniscrew anchorage (FRDMS) and compare them with those of conventional FRD and an untreated Class II control group. The sample consisted of 48 Class II subjects. Sixteen patients (13.68 ± 1.09 years of age) were treated with FRDMS, whereas 17 subjects (14.64 ± 1.56 years of age) were treated with only FRD. Also, a control sample of 15 untreated Class II subjects (14.13 ± 1.50 years of age) was constructed. Angular and linear measurements were made on 96 lateral cephalograms. Paired t, one-way analysis of variance, and Tukey tests were used for statistical analysis. Class I molar relationship and overjet correction were achieved in an average period of 6.5 ± 1.97 and 5.5 ± 1.80 months in the FRDMS and FRD groups, respectively. No skeletal effect was determined in both treatment groups. Greater overbite correction was found in the FRD group. Retrusion and extrusion of maxillary incisors, distalization of maxillary molars, and extrusion of mandibular molars were significant in both treatment groups. Labial tipping of mandibular incisors was significantly greater in the FRD group than in the FRDMS group. Overjet and molar correction was totally dentoalveolar. Unfavorable labial tipping of mandibular incisors was effectively minimized with the usage of miniscrews.

  17. A re-evaluation of localized hypoplasia of the primary canine as a marker of craniofacial osteopenia in European Upper Paleolithic infants.

    PubMed

    Skinner, M; Newell, E

    2000-01-01

    Localized hypoplasia of the primary canine (LHPC) occurs in prehistoric and contemporary populations with prevalence varying from 0 to 89%. One of the highest prevalences ever reported is Upper Paleolithic infants from Europe where 70% are affected. In that LHPC is found in relatively high proportions of contemporary children with reported or suspected malnutrition, it is important to investigate the etiology of LHPC. Previous research indicates that LHPC occurs in two steps: craniofacial osteopenia results in temporary fenestration of the cortical bone overlying the primary canine crypt; secondly, minor physical trauma to the perioral region impacts on the unprotected forming tooth crown resulting in a small pit visible on the labial surface of the erupted tooth. Investigation of the prenatal diet of mothers whose children are shown later to have LHPC found mothers are significantly low in vitamin A. Hitherto an animal model for this problem has been lacking. Recently Newell and Skinner have recognized that LHPC occurs very commonly in orangutans. Recent study of infant jaws from Pongo pygmaeus (n=75) and Pan paniscus (n=39) shows all stages of fenestration and healing of the labial bone of the primary canine crypt. 85% of orangutan and 62% of bonobos show LHPC. Current research is directed at bioavailability of vitamin A to ape infants. LHPC is a marker of malnutrition; a common factor that could link orangutan and Upper Paleolithic mothers is low dietary fat intake. A minimal level of dietary fat is required for gut absorption of both vitamin A and carotenoids.

  18. Upper lip changes and gingival exposure on smiling: vertical dimension analysis.

    PubMed

    Miron, Hagai; Calderon, Shlomo; Allon, Dror

    2012-01-01

    Our objectives were to evaluate and quantify upper lip soft-tissue changes in the vertical dimensions both at rest and at maximum smile, and to examine the correlation between upper labial vestibular attachment height and maxillary gingival exposure on smiling. Seventy-two volunteers (36 men, 36 women) aged 20 to 40 (mean, 30.49 years) were recruited for this study. For each subject, 9 measurements of upper lip position and maxillary incisor crown height at rest and in maximum smile were recorded. A statistically significant sexual dimorphism was apparent in most of the measured variables. Relaxed external upper lip length was 3.1 mm shorter in the women than in the men. The mean maxillary central incisor display at rest was 1.78 mm greater in the women than in the men. A high smile line was 2.5 times more prevalent in the women. The upper lip was shortened by 30% in subjects with a high smile line compared with 23% in subjects with a low smile line. The following findings were observed in subjects with a high smile pattern: (1) short upper lip length, (2) low smiling/resting upper lip length ratio, (3) inferior attachment of the upper labial vestibule, and (4) prominent upper lip vermilion. Copyright © 2012 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  19. [The Temporal Smile. Speech therapy for facial palsy patients after temporal lengthening myoplasty].

    PubMed

    Lambert-Prou, M-P

    2003-10-01

    We present our approach to speech therapy developed for patients with definitive peripheral facial palsy treated by temporal lengthening myoplasty. The main goal is to rehabilitate smiling function, a major component in social communication codes, by transferring labial and jugal functions to the transferred temporal muscle. Several phases are involved. The first phase, termed the Mandibular Smile involves mobilization of the mandible (original function of the temporal) by contraction of the transferred temporal and inducing an elevation of the commissura labiorum. The second phase, the Voluntary Temporal Smile is obtained by contraction of the temporal independently of mandibular movement which remains under voluntary control. The smile produces should become as symmetrical as possible. Finally, the last phase is designed to achieve a spontaneous smile independent of mandibular movement Spontaneous Temporal Smile. Temporal contraction should produce both a "real" expressive smile and good quality articulate speech, saliva evacuation, prehension, and labial junction. Acquisition of the Temporal Smile involves cerebral plasticity implying rehabilitation processes both on the peripheral and central levels.

  20. Clinical trial of tooth desensitization prior to in-office bleaching.

    PubMed

    Mehta, Deepak; Venkata, Suresh; Naganath, Meena; LingaReddy, Usha; Ishihata, Hiroshi; Finger, Werner J

    2013-10-01

    The aim of this clinical trial was to compare tooth sensitivity during and after bleaching with hydrogen peroxide gel following application of GLUMA Desensitizer PowerGel or placebo. Forty-six subjects with sound maxillary incisors and canines were enrolled. Tooth shades were determined by comparison with a Vitapan Classic Shade guide. GLUMA Desensitizer PowerGel and placebo were randomly applied to the labial surfaces of the left or right anterior teeth for 1 min, which were then rinsed and dried. Then, Opalescence Boost PF 40% gel was applied onto labial enamel for 15 min. Sensitivity scores [recorded on a 10-point visual-analog scale (VAS)] were determined before, at 5, 10, and 15 min during, and 1, 24, 48 h and 1 wk after, the bleaching treatment. Shades were determined postbleaching and after 1 wk. Prebleaching application of GLUMA Desensitizer PowerGel significantly reduced tooth sensitivity during and after bleaching when compared with treatment with placebo. The whitening effects immediately and 1 wk after bleaching were significant when compared with the prebleaching shades. In conclusion, tooth pretreatment with GLUMA Desensitizer PowerGel for 1 min prior to 15 min of in-office bleaching with 40% hydrogen peroxide gel was highly effective in reducing tooth sensitivity during and after bleaching.

  1. Regional quantitative histological variations in human oral mucosa.

    PubMed

    Ciano, Joseph; Beatty, Brian Lee

    2015-03-01

    Oral mucosa demonstrates regional variations that reflect contact with food during mastication. Though known qualitatively, our aim was to quantitatively assess regions to establish a measurable baseline from which one could compare in pathological and comparative studies, in which the abrasiveness of diets may differ. We assessed variations in the epithelial-connective tissue junction (rete ridges counts), collagen organization within the lamina propria, and elastin composition of the lamina propria of 15 regions of the labial (buccal) gingiva, lingual gingiva, vestibule, and palate. All characteristics varied more between regions within the same individual than between individuals. Lingual gingiva had high rete ridges counts, high level of collagen organization, and moderate elastin composition compared to other regions. The labial gingiva had few rete ridges, high collagen organization, and low elastin. The vestibule had the fewest average of rete ridges, least organized collagen, and high elastin. The hard palate had the highest average of rete ridges, high collagen organization, and the lowest elastin content. The soft palate conversely had the smallest average of rete ridges, moderate collagen organization, and the highest elastin composition. Our results indicate that comparison of these quantitative histological differences is warranted only for collagen organization and elastin composition. Differences in rete ridges counts were not statistically significant. Most histological characteristics observed were not significantly different between dentulous and edentulous cadavers, and the group containing all individuals. An exception was the level of collagen fiber organization within the lamina propria, which was higher in most regions when teeth were present.

  2. A “Bat” Is Easier to Learn than a “Tab”: Effects of Relative Phonotactic Frequency on Infant Word Learning

    PubMed Central

    Gonzalez-Gomez, Nayeli; Poltrock, Silvana; Nazzi, Thierry

    2013-01-01

    Many studies have shown that during the first year of life infants start learning the prosodic, phonetic and phonotactic properties of their native language. In parallel, infants start associating sound sequences with semantic representations. However, the question of how these two processes interact remains largely unknown. The current study explores whether (and when) the relative phonotactic probability of a sound sequence in the native language has an impact on infants’ word learning. We exploit the fact that Labial-Coronal (LC) words are more frequent than Coronal-Labial (CL) words in French, and that French-learning infants prefer LC over CL sequences at 10 months of age, to explore the possibility that LC structures might be learned more easily and thus at an earlier age than CL structures. Eye movements of French-learning 14- and 16-month-olds were recorded while they watched animated cartoons in a word learning task. The experiment involved four trials testing LC sequences and four trials testing CL sequences. Our data reveal that 16-month-olds were able to learn the LC and CL words, while14-month-olds were only able to learn the LC words, which are the words with the more frequent phonotactic pattern. The present results provide evidence that infants’ knowledge of their native language phonotactic patterns influences their word learning: Words with a frequent phonotactic structure could be acquired at an earlier age than those with a lower probability. Developmental changes are discussed and integrated with previous findings. PMID:23527227

  3. Drag Reduction in a Natural High-Frequency Swinging Micro-Articulation: Mouthparts of the Honey Bee.

    PubMed

    Shi, Guanya; Wu, Jianing; Yan, Shaoze

    2017-01-01

    Worker-bee mouthparts consist of the glossa, the galeae and the vestigial labial palp, and it is these structures that enable bees to feed themselves. The articulation joints, 60∼70 µm in diameter, are present on the tip of the labial palp and are covered with olfactory sensilla, allowing movements between the segments. Using a specially designed high-speed camera system, we discovered that the articulation joint could swing in the nectar at a frequency of ∼50 Hz, considerably higher than the usual motion frequency of mammalian joints. To understand the potential drag reduction in this tiny organ, we examined its microstructure and also its surface wettability. We found that chitinous semispherical protuberances (4∼6 µm in diameter) are uniformly scattered on the surface of the joint and, moreover, that the surface is hydrophobic. We proposed a hydrodynamic model and revealed that the specialized surface can effectively reduce the mean equivalent friction (Ff) by ∼10%, through the use of protuberances immersed in the liquid feed. Theoretical results indicated that the dimensions of such protuberances are the predominant factor in minimizing Ff, and that the natural dimensions of the protuberances are close to the theoretical optimum at which friction is at a minimum. These discoveries may inspire the design of high-frequency micro-joints for engineering applications, such as in micro-stirrers. © The Authors 2017. Published by Oxford University Press on behalf of Entomological Society of America.

  4. Focal Epithelial Hyperplasia in Adult Patients With HIV Infection: Clearance With Topical Imiquimod.

    PubMed

    Méndez-Flores, Silvia; Esquivel-Pedraza, Lilly; Hernández-Salazar, Amparo; Charli-Joseph, Yann; Saeb-Lima, Marcela

    2016-01-01

    Case 1 A 41-year-old man with human immunodeficiency virus (HIV) 1 diagnosed 16 years prior to his consultation was referred for an 8-month history of multiple painless lumps in his mouth. He had A2 status (CD4 cell count of 273 cells/mm(3) and viral load of 43,000 copies/L) and was taking treatment with lamivudine/zidovudine (combivir) and efavirenz. Physical examination showed multiple small mucosal-colored and lobulated papulonodules located in the palate and lower gingiva and a whitish verrucous plaque on the lower labial mucosa (Figure 1a). The lesions were diagnosed clinically as focal epithelial hyperplasia (FEH) and further confirmed by classical histopathological findings (Figure 1b). He had previously received unspecified treatment; thus, topical 5% imiquimod cream was initiated every night. Mild erosion and ulceration developed in the upper labial mucosa, which were managed with lubrication (petrolatum ointment). After 2 weeks, all of the small lesions disappeared and the largest plaque resolved 1 week later (Figure 1c). A small residual mass in the area of biopsy, suggesting a scar, remained on the lower lip. The area was removed surgically and corresponded to fibrosis histologically, with no evidence of human papillomavirus (HPV) infection. CD4 cell count (694 cells/mm(3)) and viral load (<40 copies/L) did not show remarkable changes after imiquimod administration. No serious side effects were observed and the patient has remained free of disease after 1 year of follow-up.

  5. Nickel Gluconate-Mercurius Heel-Potentised Swine Organ Preparations: a new therapeutical approach for the primary treatment of pediatric ranula and intraoral mucocele.

    PubMed

    Garofalo, Salvatore; Briganti, Vito; Cavallaro, Sebastiano; Pepe, Ernesto; Prete, Marina; Suteu, Liana; Tavormina, Paolo

    2007-02-01

    Many authors consider surgical therapy of pediatric ranula and intraoral mucocele as the election treatment. Recently, an intracystic sclerosing injection with OK-432 has been proposed as a ranula primary treatment. This preliminary study evaluates the effectiveness of the use of Nickel Gluconate-Mercurius Heel-Potentised Swine Organ Preparations as the primary treatment of pediatric ranula and intraoral mucocele. Eighteen children (9 ranulas, 9 labial mucoceles, 2 lingual mucoceles) were treated with oral administration of Nickel Gluconate-Mercurius Heel-Potentised Swine Organ Preparations D10/D30/D200. Eighty-nine percent ranulas (8 out of 9), 67% labial mucoceles (6 out of 9) completely responded to the therapy. One ranula, that interrupted therapy after only 4 weeks, was subjected to marsupialization in another hospital. A double mucocele case partially responded (one of the two was extinguished), another case incompletely responded, decreasing the size beyond 50%, and just one case, changing volume, resisted the therapy. Lingual mucocele healed at once. Blandin-Nuhn polypoid congenital mucocele responded to the treatment with gradual reabsorption, permitting surgical excision of the atrophic polypoid remnant, without removing glands of origin. No solved case showed recurrence (follow up range: 4-32 months). Homotoxicological therapy with Nickel Gluconate-Mercurius Heel-Potentised Swine Organ Preparations D10/D30/D200 is an effective primary treatment of pediatric ranula and intraoral mucocele.

  6. Glycoprotein 340 and sialic acid in minor-gland and whole saliva of children, adolescents, and adults.

    PubMed

    Sonesson, Mikael; Ericson, Dan; Kinnby, Bertil; Wickström, Claes

    2011-12-01

    Glycoprotein 340 (gp-340) is a bacterial-binding glycoprotein found in major-gland and minor-gland saliva. Sialic acid, a common terminal structure of salivary glycoproteins, interacts with microorganisms and host ligands, as well as with free radicals. This study investigated the contents of gp-340 and sialic acid in minor-gland saliva and whole saliva of children (3 yr of age), adolescents (14 yr of age), and adults (20-25 yr of age). Labial-gland saliva and buccal-gland saliva were collected on filter paper, and unstimulated whole saliva was collected by draining into a tube. The relative amount of gp-340 and sialic acid was determined by ELISA and by enzyme-linked lectin assay (ELLA), respectively. In minor-gland saliva, no statistically significant differences in gp-340 and sialic acid were seen between the age-groups. Among adults, significantly lower amounts of gp-340 and sialic acid were seen in labial saliva compared with buccal saliva. In whole saliva, the amount of gp-340 was significantly lower among adults compared with children. No differences between genders were seen. Stable content of gp-340 and sialic acid in minor-gland saliva across the age-groups, and a higher content of gp-340 in the whole saliva of the youngest age-group (3-yr-olds) compared with the adult group, may reflect that those components are vital innate factors of immunity in children's saliva.

  7. A biomechanical modeling study of the effects of the orbicularis oris muscle and jaw posture on lip shape.

    PubMed

    Stavness, Ian; Nazari, Mohammad Ali; Perrier, Pascal; Demolin, Didier; Payan, Yohan

    2013-06-01

    The authors' general aim is to use biomechanical models of speech articulators to explore how possible variations in anatomical structure contribute to differences in articulatory strategies and phone systems across human populations. Specifically, they investigated 2 issues: (a) the link between lip muscle anatomy and variability in lip gestures and (b) the constraints of coupled lip/jaw biomechanics on jaw posture in labial sounds. The authors used a model coupling the jaw, tongue, and face. First, the influence of the orbicularis oris (OO) anatomical implementation was analyzed by assessing how changes in depth (from epidermis to the skull) and peripheralness (proximity to the lip horn center) affected lip shaping. Second, the capability of the lip/jaw system to generate protrusion and rounding, or labial closure, was evaluated for different jaw heights. Results showed that a peripheral and moderately deep OO implementation is most appropriate for protrusion and rounding; a superficial implementation facilitates closure; protrusion and rounding require a high jaw position; and closure is achievable for various jaw heights. Models provide objective information regarding possible links between anatomical and speech production variability across humans. Comparisons with experimental data will illustrate how motor control and cultural factors cope with these constraints.

  8. Drag Reduction in a Natural High-Frequency Swinging Micro-Articulation: Mouthparts of the Honey Bee

    PubMed Central

    Shi, Guanya; Wu, Jianing

    2017-01-01

    Worker-bee mouthparts consist of the glossa, the galeae and the vestigial labial palp, and it is these structures that enable bees to feed themselves. The articulation joints, 60∼70 µm in diameter, are present on the tip of the labial palp and are covered with olfactory sensilla, allowing movements between the segments. Using a specially designed high-speed camera system, we discovered that the articulation joint could swing in the nectar at a frequency of ∼50 Hz, considerably higher than the usual motion frequency of mammalian joints. To understand the potential drag reduction in this tiny organ, we examined its microstructure and also its surface wettability. We found that chitinous semispherical protuberances (4∼6 µm in diameter) are uniformly scattered on the surface of the joint and, moreover, that the surface is hydrophobic. We proposed a hydrodynamic model and revealed that the specialized surface can effectively reduce the mean equivalent friction (Ff) by ∼10%, through the use of protuberances immersed in the liquid feed. Theoretical results indicated that the dimensions of such protuberances are the predominant factor in minimizing Ff, and that the natural dimensions of the protuberances are close to the theoretical optimum at which friction is at a minimum. These discoveries may inspire the design of high-frequency micro-joints for engineering applications, such as in micro-stirrers. PMID:28355472

  9. Cross-linguistic preference and the phonetics of geminates: Place of articulation and duration of phonologically short and long consonants in Guinaang Bontok

    NASA Astrophysics Data System (ADS)

    Aoyama, Katsura

    2003-10-01

    It is reported that there is a preference for the place-of-articulation in geminates among world languages; alveolar, labial, velar geminate consonants always appear in that order with respect to one another (G. Thurgood, Papers in Honor of Frederick H. Brengelman, 1993, pp. 129-137). This study investigated whether the phonetic contrasts in duration are larger in cross-linguistically favored place-of-articulation (e.g., alveolar) than in the less favored place-of-articulation (e.g., velar). The data is from a language called Guinaang Bontok. Four speakers of Guinaang Bontok produced thirty-five words that have either a singleton or a geminate of /p t k m n rhookn/. Eighteen words included a singleton and the other seventeen words included a geminate. The participants produced the target word in isolation first, and then repeated it in a frame sentence twice. The recordings were digitized at 22.05 Hz, and the durations of the consonants were measured. A total of 420 tokens (35 words ×3 repetitions ×4 participants) were analyzed. The results partially supported the hypothesis; the durational contrasts were indeed larger in alveolar consonants (/t n/) than in labial consonants (/p m/) and velar consonants (/rhookn/). However, contrasts in velar stop (/k/) were as large as in the alveolar stop (/t/).

  10. Face-referenced measurement of perioral stiffness and speech kinematics in Parkinson's disease.

    PubMed

    Chu, Shin Ying; Barlow, Steven M; Lee, Jaehoon

    2015-04-01

    Perioral biomechanics, labial kinematics, and associated electromyographic signals were sampled and characterized in individuals with Parkinson's disease (PD) as a function of medication state. Passive perioral stiffness was sampled using the OroSTIFF system in 10 individuals with PD in a medication ON and a medication OFF state and compared to 10 matched controls. Perioral stiffness, derived as the quotient of resultant force and interoral angle span, was modeled with regression techniques. Labial movement amplitudes and integrated electromyograms from select lip muscles were evaluated during syllable production using a 4-D computerized motion capture system. Multilevel regression modeling showed greater perioral stiffness in patients with PD, consistent with the clinical correlate of rigidity. In the medication-OFF state, individuals with PD manifested greater integrated electromyogram levels for the orbicularis oris inferior compared to controls, which increased further after consumption of levodopa. This study illustrates the application of biomechanical, electrophysiological, and kinematic methods to better understand the pathophysiology of speech motor control in PD.

  11. An articulatory-perceptual account of vocalization and elision of dark /l/ in the Romance languages.

    PubMed

    Recasens, D

    1996-01-01

    This investigation seeks to understand the factors causing vocalization and elision of dark/l/ in the Romance languages. Contrary to articulatory- and perceptual-based arguments in the literature it is claimed that preconsonantal vocalization conveys the phonemic categorization of the /w/-like formant transitions generated by the tongue dorsum retraction gesture (in a similar fashion to other processes such as /[symbol: see text] /Vjn/). The evolution /VwlC/ > /VwC/ may be explained using articulatory and perceptual arguments. A dissimilatory perceptual mechanism is required in order to account for a much higher frequency of vocalizations before dentals and alveolars than before labials and velars in the Romance languages. Through this process listeners assign the gravity property of dark /l/ to a following grave labial or velar consonant but not so to a following acute dental or alveolar consonant in spite of the alveolar lateral being equally dark (i.e., grave) in the three consonantal environments. Other articulatory facts appear to play a role in the vocalization of final /l/ (i.e., the occurrence of closure after voicing has ceased) and of geminate /ll/ (i.e., its being darker than non-geminate /l/). The elision of dark /l/ may occur preconsonantally and word finally either after vocalization has applied or not. This study illustrates the multiple causal factors and the articulatory-perceptual nature of sound change processes.

  12. Commentary on: periodontally accelerated osteogenic orthodontics (PAOO) - a clinical dilemma.

    PubMed

    Binderman, Itzhak; Gadban, Nasser; Bahar, Hila; Herman, Avishai; Yaffe, Avinoam

    2010-09-01

    It is apparent that tooth movement is enhanced by procedures that elevate the remodeling of alveolar bone, and of periodontal and gingival fibrous tissues. The periodontally accelerated osteogenic orthodontics (PAOO) also termed as Wilckodontics, involves full-thickness labial and lingual alveolar flaps accompanied with limited selective labial and lingual surgical scarring of cortical bone (corticotomy). Most of the authors suggest that the RAP is the major stimulus for alveolar bone remodeling, enabling the PAOO. However, we propose that detachment of the bulk of dentogingival and interdental fibers from coronal part of root surfaces by itself should suffice to stimulate alveolar bone resorption mainly on its PDL surfaces, leading to widening of the periodontal ligament space which largely attributes to accelerated osteogenic orthodontics. Moreover this limited fiberotomy also disrupts transiently the positional physical memory of dentition (PPMD), allowing accelerated tooth movement. During retention period, a new biological and physical connectivity is generated that could be termed as new positional memory of the dental arch.

  13. Nonsurgical and nonextraction treatment of skeletal Class III open bite: its long-term stability.

    PubMed

    Kondo, E; Aoba, T J

    2000-03-01

    Two female patients, aged 14 years 5 months and 17 years 3 months with skeletal Class III open bite and temporomandibular dysfunction are presented. They had previously been classified as orthognathic surgical cases, involving first premolar removal. The primary treatment objective was to eliminate those skeletal and neuromuscular factors that were dominant in establishing their malocclusions. These included abnormal behavior of the tongue with short labial and lingual frenula, bilateral imbalance of chewing muscles, a partially blocked nasopharyngeal airway causing extrusion of the molars, with rotation of the mandible and narrowing of the maxillary arch. Resultant occlusal interference caused the mandible to shift to one side, which in turn produced the abnormal occlusal plane and curve of Spee. As a result, the form and function of the joints were adversely affected by the structural and functional asymmetry. These cases were treated by expanding the maxillary arch, which brought the maxilla downward and forward. The mandible moved downward and backward, with a slight increase in anterior facial height. Intruding and uprighting the posterior teeth, combined with a maxillary protraction, reconstructed the occlusal plane. A favorable perioral environment was created with widened tongue space in order to produce an adequate airway. Myofunctional therapy after lingual and labial frenectomy was assisted by vigorous gum chewing during and after treatment, together with a tooth positioner. Normal nasal breathing was achieved.

  14. Marginal adaptation of Spinell InCeram and feldspathic porcelain laminate veneers.

    PubMed

    Ghaffari, Tahereh; Hamedi-Rad, Fahimeh; Fakhrzadeh, Vahid

    2016-01-01

    This in vitro study investigated the marginal fit of two porcelain laminate veneers to help the selection of more accurate veneers in discolored teeth. Thirty impressions of metal master die created from the prepared labial surface of an acrylic maxillary central incisor were made and poured with Type IV stone. The dies were distributed into test groups (n = 15) for the construction of DuCeram and InCeram laminate veneers. An image-analysis program was used to measure the gap between the veneers and the master die at the labial, lingual, and proximal margins. Statistical analysis was performed with repeated measures ANOVA. Independent t-test was used to compare the mean values between the two groups. Values of P < 0.05 were judged to be significant. Differences between marginal fit of two groups were significant (P < 0.001). The overall mean marginal gap values (μm) for InCeram and DuCeram were, respectively, 114.4 ± 40.81 and 282.3 ± 82.82. Independent t-test revealed significant differences between the marginal gaps of two materials at different predetermined points. Within the limitations of this study, the marginal gap in InCeram laminate veneer was within the clinically acceptable standard set at 120 μm.

  15. Vertical dimension of the face analyzed by digital photographs.

    PubMed

    Gomes, Vanderlei L; Gonçalves, Luiz C; Correia, Caio L M; Lucas, Bárbara L; Carvalho, Polliane M

    2008-01-01

    Esthetics is a primary consideration for patients seeking prosthodontic treatment. The alteration of the facial vertical dimension can deteriorate the orofacial harmony. When it is essential to assess dentofacial attractiveness, there is a consensus in the research community that the soft tissue evaluation in digital photographs is much more consistent than the traditional cephalometric analyses. The aim of this study was to compare the lower third of the face with the facial segment (ie, the distance between the outer cantus of the eye and the labial commissural), to verify whether or not there are statistical correlations and significant differences between them. Front-view standardized digital photographs of 84 dentate Brazilian subjects were used to measure all facial segments through an image-processing program. The Student ttest showed no significant difference between the left facial segment and the lower third of the face. Pearson's product-moment coefficient showed significant correlations between both facial segments and the lower third of the face. After the regression analysis, two mathematical equations were used to correlate the facial segment to the lower third of the face. The distance between the outer cantus of the eye and the labial commissurae can be a reliable guide to estimate the vertical dimension of the rest position. Moreover, when it is measured on the left side of the face there is a better chance to correctly estimate the appropriate size.

  16. Piezoelectric surgery in mandibular split crest technique with immediate implant placement: a case report.

    PubMed

    Belleggia, F; Pozzi, A; Rocci, M; Barlattani, A; Gargari, M

    2008-10-01

    Implant supported rehabilitation of thin edentulous ridges with horizontal atrophy necessitates a regenerative approach. Within the procedures for horizontal bone defects augmentation, ridge expansion techniques permit dislocation of the buccal bone plate in a labial direction and simultaneous implant insertion in single-stage surgery, abbreviating overall treatment time.The piezoelectric ridge expansion technique permits to obtain the expansion of very mineralized bone crests without excessive traumas or the risk of ridge fractures. The case reported shows an implant treatment for partial edentulous lower arch rehabilitation. A full-split thickness flap was raised. The mucoperiosteal reflection permitted to identify alveolar crest contour where osteotomies had to be performed. Split thickness dissection allowed periosteal blood supply to be mainteined on the buccal bone plate. After horizontal and vertical osteotomies were performed with OT7 piezoelectric microsaw (Piezo-surgery, Mectron), a single-bevel scalpel was used to move the buccal bone plate to the labial. Two Straumann TE 3.3/4.8 mm wide implants were inserted in the lower right premolar area, and 1 Straumann 4.8 mm Wide Neck implant was inserted to replace lower right first molar. The amount of bone expansion was equal to the cervical diameter of the placed implants (4.8 mm) and residual bone gap was packed with Bio-Oss granules (Geistlich). Healing was uneventful and 3 months later final restorations with implant-supported porcelain-fused-to-metal crowns were cemented.

  17. Transfer of training of a new linguistic contrast in voicing

    PubMed Central

    McCLASKEY, CYNTHIA L.; PISONI, DAVID B.; CARRELL, THOMAS D.

    2012-01-01

    The present study examined the plasticity of the human perceptual system by means of laboratory training procedures designed to modify the perception of the voicing dimension in synthetic speech stimuli. Although the results of earlier laboratory training studies have been ambiguous, recently Pisoni, Aslin, Perey, and Hennessy (1982) have succeeded in altering the perception of labial stop consonants from a two-way contrast in voicing to a three-way contrast. The present study extended these initial results by demonstrating that experience gained from discrimination training on one place of articulation (e.g., labial) can be transferred to another place of articulation (e.g., alveolar) without any additional training on the specific test stimuli. Quantitative analyses of the identification functions showed that the new percoptual categories were stable and displayed well-defined labeling boundaries between categories. Taken together with the earlier findings, these results imply a greater degree of plasticity in the adult speech processing system than has generally been acknowledged in past studies. PMID:6657433

  18. Miescher's cheilitis granulomatosa. A presentation of five cases.

    PubMed

    Camacho-Alonso, Favio; Bermejo-Fenoll, Ambrosio; López-Jornet, Pía

    2004-01-01

    Miescher's cheilitis granulomatosa (CG) consists of the appearance of recurrent labial edema on one or both lips, which can become persistent. It has traditionally been considered as a monosymptomatic form of the Melkersson-Rosenthal syndrome, described as the association of recurrent labial and/or recurrent facial edema, relapsing facial paralysis and fissured tongue. The aim of this study is to present a series of five clinically and histopathologically diagnosed cases of CG that came to our clinic at the Teaching Unit of Oral Medicine, Faculty of Medicine and Odontology, University of Murcia. A complete study of these patients evaluated the age, sex, family history, and location and course of the signs and symptoms. Various complementary examinations were carried out, studying the hematic characteristics (hemogram, erythrocyte sedimentation rate, leukocyte count), including immunological and histopathological studies. The treatment consisted of intralesional corticoids, combined in some cases with anti-leprous drugs or systemic corticoids. A good response to treatment was obtained in all cases.

  19. Ureaplasmas and mycoplasmas in vaginal samples from prepubertal girls and the reasons for gynecological consultation.

    PubMed

    Romero, Patricia; Muñoz, Mónica; Martínez, María Angélica; Romero, María Inés; Germain, Laura; Maida, Margarita; Quintanilla, Viviana; del Río, María Teresa

    2014-02-01

    The aim of the study was to evaluate vaginal colonization with Ureaplasmaurealyticum (UU) and Mycoplasma hominis (MH) in prepubertal girls and reason for gynecological consultation. All prepubertal girls sent for consultation for medical issues to a pediatric gynecology department. Vaginal swabs were obtained for culture and were seeded using specific media. Patients colonized with genital mycoplasmas (GMs) were evaluated by a psychologist to rule out sexual abuse (SA). A total of119 patients were included. The mean age was 5.9 y. Reasons for consultation were vulvovaginitis in 78 (66%), SA before study entry in 19 (16%), labial adhesion in 8 (7%), genital bleeding in 8 (7%), suspected sexual abuse in 3 (3%) and 1 patient was sent for consultation for labial adhesion but had a normal examination (1%), physical neglect in 1 (1%), and genital ulcers in 1 (1%). UU was isolated in 14 (12%) MH was isolated in 3 (3%). UU was isolated in 9 patents (47%) with SA before study entry. Five patients colonized with UU that had consulted for other reasons were evaluated by a pediatric psychologist; 4 disclosed SA. One patient colonized with UU did not disclose SA. Patients with GMs were more likely to disclose sexual abuse (UU P < .0001. MH P < .0065). GMs were isolated more in SA cases. Patients colonized with GMs and consulted for other issues than SA were more likely to disclose SA. Copyright © 2014 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

  20. [A case report on Waardenburg syndrome with cleft lip].

    PubMed

    Traoré, H; Traoré, D; Ouane, O; Simpara, B; Ongoiba, N

    2011-01-01

    The syndrome of Waardenburg is a congenital plurimal formatif unit rare described and individualized for the first time by Waardenburg in 1951. It associates in its form most typical dystopie canthale intern, a widening of the base of the nose, disorders of the pigmentation. We wanted brought back this case because of its scarcity. It was about a 18 month old infant without particular antecedents, which was drawn up to us for correction of congenital malformation. The interrogation did not make it possible to find signs functional notable. With the examination it had a general good state. t presented a bilateral iridal hypochromy, a dystopie canthale, a canitie, a bilateral labial slit. The diagnosis of presumption was the Syndrome of Waardenburg because of the description of at least 2 major signs: dystopie canthale and disorders of the pigmentation. The complementary examinations carried out were those of the preoperative assessment which returned normal. The biological diagnosis which rests on the search for change of gene was not made for reasons of technical order and financier. The surgery is centered on the treatment of the labial slit. A chéiloplastie according to Millard was carried out. The continuations were simple. The Syndrome of Waardenburg is a rare, hereditary entity. A neurosensory deafness, musculo-skeletal anomalies, thus qu' a disease of Hirschsprung will have to be systematically required. The surgery of the slit or the télécanthus allows an social integration of the subjects reached.