NATIONAL RISK MANAGEMENT RESEARCH LABORATORY - PROVIDING SOLUTIONS FOR A BETTER TOMORROW

EPA Science Inventory

As part of the U.S. Environmental Protection Agency's Office of Research and Development, the National Risk Management Research Laboratory (NRMRL) conducts research into ways to prevent and reduce pollution risks that threaten human health and the environment. The laboratory inve...

Research Update: The USDA-ARS-Conservation and Production Research Laboratory, Bushland, Texas

USDA-ARS?s Scientific Manuscript database

This presentation/manuscript provide a brief summary of beef cattle feeding-related research conducted at the USDA-ARS-Conservation and Production Research Laboratory, Bushland, Texas, over the past four years. It summarizes data that has been published in scientific journals, in symposia and confer...

Artist's Concept of NASA's Propulsion Research Laboratory

NASA Technical Reports Server (NTRS)

2002-01-01

A new, world-class laboratory for research into future space transportation technologies is under construction at the Marshall Space Flight Center (MSFC) in Huntsville, AL. The state-of-the-art Propulsion Research Laboratory will serve as a leading national resource for advanced space propulsion research. Its purpose is to conduct research that will lead to the creation and development of irnovative propulsion technologies for space exploration. The facility will be the epicenter of the effort to move the U.S. space program beyond the confines of conventional chemical propulsion into an era of greatly improved access to space and rapid transit throughout the solar system. The Laboratory is designed to accommodate researchers from across the United States, including scientists and engineers from NASA, the Department of Defense, the Department of Energy, universities, and industry. The facility, with 66,000 square feet of useable laboratory space, will feature a high degree of experimental capability. Its flexibility will allow it to address a broad range of propulsion technologies and concepts, such as plasma, electromagnetic, thermodynamic, and propellantless propulsion. An important area of emphasis will be development and utilization of advanced energy sources, including highly energetic chemical reactions, solar energy, and processes based on fission, fusion, and antimatter. The Propulsion Research Laboratory is vital for developing the advanced propulsion technologies needed to open up the space frontier, and will set the stage of research that could revolutionize space transportation for a broad range of applications.

Research and the planned Space Experiment Research and Processing Laboratory

NASA Technical Reports Server (NTRS)

2000-01-01

Original photo and caption dated October 8, 1991: 'Plant researchers Neil Yorio and Lisa Ruffe prepare to harvest a crop of Waldann's Green Lettuce from KSC's Biomass Production Chamber (BPC). KSC researchers have grown several different crops in the BPC to determine which plants will better produce food, water and oxygen on long-duration space missions.' Their work is an example of the type of life sciences research that will be conducted at the Space Experiment Research Procession Laboratory (SERPL). The SERPL is a planned 100,000-square-foot laboratory that will provide expanded and upgraded facilities for hosting International Space Station experiment processing. In addition, it will provide better support for other biological and life sciences payload processing at KSC. It will serve as a magnet facility for a planned 400-acre Space Station Commerce Park.

Research and the planned Space Experiment Research and Processing Laboratory

NASA Technical Reports Server (NTRS)

2000-01-01

Original photo and caption dated October 8, 1991: 'Plant researchers Lisa Ruffe and Neil Yorio prepare to harvest a crop of Waldann's Green Lettuce from KSC's Biomass Production Chamber (BPC). KSC researchers have grown several different crops in the BPC to determine which plants will better produce food, water and oxygen on long-duration space missions.' Their work is an example of the type of life sciences research that will be conducted at the Space Experiment Research Procession Laboratory (SERPL). The SERPL is a planned 100,000-square-foot laboratory that will provide expanded and upgraded facilities for hosting International Space Station experiment processing. In addition, it will provide better support for other biological and life sciences payload processing at KSC. It will serve as a magnet facility for a planned 400-acre Space Station Commerce Park.

FRESHWATER FINDINGS, 1979-1982: RESEARCH PUBLICATIONS OF THE ENVIRONMENTAL RESEARCH LABORATORY, DULUTH, MINNESOTA

EPA Science Inventory

This report contains citations of publications for the years 1979-1982 on research conducted or supported by the Environmental Research Laboratory-Duluth. All published material has been organized into two major categories: (1) Journal Articles, Book Chapters, Proceedings, etc., ...

Idaho National Laboratory Research & Development Impacts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stricker, Nicole

Technological advances that drive economic growth require both public and private investment. The U.S. Department of Energy’s national laboratories play a crucial role by conducting the type of research, testing and evaluation that is beyond the scope of regulators, academia or industry. Examples of such work from the past year can be found in these pages. Idaho National Laboratory’s engineering and applied science expertise helps deploy new technologies for nuclear energy, national security and new energy resources. Unique infrastructure, nuclear material inventory and vast expertise converge at INL, the nation’s nuclear energy laboratory. Productive partnerships with academia, industry and governmentmore » agencies deliver high-impact outcomes. This edition of INL’s Impacts magazine highlights national and regional leadership efforts, growing capabilities, notable collaborations, and technology innovations. Please take a few minutes to learn more about the critical resources and transformative research at one of the nation’s premier applied science laboratories.« less

Laboratory Directed Research and Development LDRD-FY-2011

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dena Tomchak

2012-03-01

This report provides a summary of the research conducted at the Idaho National Laboratory (INL) during Fiscal Year (FY) 2011. This report demonstrates the types of cutting edge research the INL is performing to help ensure the nation's energy security. The research conducted under this program is aligned with our strategic direction, benefits the Department of Energy (DOE) and is in compliance with DOE order 413.2B. This report summarizes the diverse research and development portfolio with emphasis on the DOE Office of Nuclear Energy (DOE-NE) mission, encompassing both advanced nuclear science and technology and underlying technologies.

Integrating teaching and research in the field and laboratory settings

NASA Astrophysics Data System (ADS)

Wang, L.; Kaseke, K. F.; Daryanto, S.; Ravi, S.

2015-12-01

Field observations and laboratory measurements are great ways to engage students and spark students' interests in science. Typically these observations are separated from rigorous classroom teaching. Here we assessed the potential of integrating teaching and research in the field and laboratory setting in both US and abroad and worked with students without strong science background to utilize simple laboratory equipment and various environmental sensors to conduct innovative projects. We worked with students in Namibia and two local high school students in Indianapolis to conduct leaf potential measurements, soil nutrient extraction, soil infiltration measurements and isotope measurements. The experience showed us the potential of integrating teaching and research in the field setting and working with people with minimum exposure to modern scientific instrumentation to carry out creative projects.

The viability of establishing collaborative, reconfigurable research environments for the Human Performance Research Laboratory at NASA Ames

NASA Technical Reports Server (NTRS)

Clipson, Colin

1994-01-01

This paper will review and summarize research initiatives conducted between 1987 and 1992 at NASA Ames Research Center by a research team from the University of Michigan Architecture Research Laboratory. These research initiatives, funded by a NASA grant NAG2-635, examined the viability of establishing collaborative, reconfigurable research environments for the Human Performance Research Laboratory at NASA Ames in California. Collaborative Research Environments are envisioned as a way of enhancing the work of NASA research teams, optimizing the use of shared resources, and providing superior environments for housing research activities. The Integrated Simulation Project at NASA, Ames Human Performance Research Laboratory is one of the current realizations of this initiative.

Research and the planned Space Experiment Research and Processing Laboratory

NASA Technical Reports Server (NTRS)

2000-01-01

Original photo and caption dated June 22, 1988: 'A dwarf wheat variety known as Yecoro Rojo flourishes in KSC's Biomass Production Chamber. Researchers are gathering information on the crop's ability to produce food, water and oxygen, and then remove carbon dioxide. The confined quarters associated with space travel require researchers to focus on smaller plants that yield proportionately large amounts of biomass. This wheat crop takes about 85 days to grow before harvest.' Plant experiments such as this are the type of life sciences research that will be conducted at the Space Experiment Research Procession Laboratory (SERPL). The SERPL is a planned 100,000-square-foot laboratory that will provide expanded and upgraded facilities for hosting International Space Station experiment processing. In addition, it will provide better support for other biological and life sciences payload processing at KSC. It will serve as a magnet facility for a planned 400-acre Space Station Commerce Park.

Nano-G research laboratory for a spacecraft

NASA Technical Reports Server (NTRS)

Vonbun, Friedrich O. (Inventor); Garriott, Owen K. (Inventor)

1991-01-01

An acceleration free research laboratory is provided that is confined within a satellite but free of any physical engagement with the walls of the satellite, wherein the laboratory has adequate power, heating, cooling, and communications services to conduct basic research and development. An inner part containing the laboratory is positioned at the center-of-mass of a satellite within the satellite's outer shell. The satellite is then positioned such that its main axes are in a position parallel to its flight velocity vector or in the direction of the residual acceleration vector. When the satellite is in its desired orbit, the inner part is set free so as to follow that orbit without contacting the inside walls of the outer shell. Sensing means detect the position of the inner part with respect to the outer shell, and activate control rockets to move the outer shell; thereby, the inner part is repositioned such that it is correctly positioned at the center-of-mass of the satellite. As a consequence, all disturbing forces, such as drag forces, act on the outer shell, and the inner part containing the laboratory is shielded and is affected only by gravitational forces. Power is supplied to the inner part and to the laboratory by a balanced microwave/laser link which creates the kind of environment necessary for basic research to study critical phenomena such as the Lambda transition in helium and crystal growth, and to perform special metals and alloys research, etc.

Integrating teaching and authentic research in the field and laboratory settings

NASA Astrophysics Data System (ADS)

Daryanto, S.; Wang, L.; Kaseke, K. F.; Ravi, S.

2016-12-01

Typically authentic research activities are separated from rigorous classroom teaching. Here we assessed the potential of integrating teaching and research activities both in the field and in the laboratory. We worked with students from both US and abroad without strong science background to utilize advanced environmental sensors and statistical tool to conduct innovative projects. The students include one from Namibia and two local high school students in Indianapolis (through Project SEED, Summer Experience for the Economically Disadvantaged). They conducted leaf potential measurements, isotope measurements and meta-analysis. The experience showed us the great potential of integrating teaching and research in both field and laboratory settings.

Dental Laboratory Technology. Project Report Phase I with Research Findings.

ERIC Educational Resources Information Center

Sappe', Hoyt; Smith, Debra S.

This report provides results of Phase I of a project that researched the occupational area of dental laboratory technology, established appropriate committees, and conducted task verification. These results are intended to guide development of a program designed to train dental laboratory technicians. Section 1 contains general information:…

Mobile robotics research at Sandia National Laboratories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Morse, W.D.

Sandia is a National Security Laboratory providing scientific and engineering solutions to meet national needs for both government and industry. As part of this mission, the Intelligent Systems and Robotics Center conducts research and development in robotics and intelligent machine technologies. An overview of Sandia`s mobile robotics research is provided. Recent achievements and future directions in the areas of coordinated mobile manipulation, small smart machines, world modeling, and special application robots are presented.

Use of the NASA Space Radiation Laboratory at Brookhaven National Laboratory to Conduct Charged Particle Radiobiology Studies Relevant to Ion Therapy

PubMed Central

Held, Kathryn D.; Blakely, Eleanor A.; Story, Michael D.; Lowenstein, Derek I.

2016-01-01

Although clinical studies with carbon ions have been conducted successfully in Japan and Europe, the limited radiobiological information about charged particles that are heavier than protons remains a significant impediment to exploiting the full potential of particle therapy. There is growing interest in the U.S. to build a cancer treatment facility that utilizes charged particles heavier than protons. Therefore, it is essential that additional radiobiological knowledge be obtained using state-of-the-art technologies and biological models and end points relevant to clinical outcome. Currently, most such ion radiotherapy-related research is being conducted outside the U.S. This article addresses the substantial contributions to that research that are possible at the NASA Space Radiation Laboratory (NSRL) at Brookhaven National Laboratory (BNL), which is the only facility in the U.S. at this time where heavy-ion radiobiology research with the ion species and energies of interest for therapy can be done. Here, we briefly discuss the relevant facilities at NSRL and how selected charged particle biology research gaps could be addressed using those facilities. PMID:27195609

Use of the NASA Space Radiation Laboratory at Brookhaven National Laboratory to Conduct Charged Particle Radiobiology Studies Relevant to Ion Therapy.

PubMed

Held, Kathryn D; Blakely, Eleanor A; Story, Michael D; Lowenstein, Derek I

2016-06-01

Although clinical studies with carbon ions have been conducted successfully in Japan and Europe, the limited radiobiological information about charged particles that are heavier than protons remains a significant impediment to exploiting the full potential of particle therapy. There is growing interest in the U.S. to build a cancer treatment facility that utilizes charged particles heavier than protons. Therefore, it is essential that additional radiobiological knowledge be obtained using state-of-the-art technologies and biological models and end points relevant to clinical outcome. Currently, most such ion radiotherapy-related research is being conducted outside the U.S. This article addresses the substantial contributions to that research that are possible at the NASA Space Radiation Laboratory (NSRL) at Brookhaven National Laboratory (BNL), which is the only facility in the U.S. at this time where heavy-ion radiobiology research with the ion species and energies of interest for therapy can be done. Here, we briefly discuss the relevant facilities at NSRL and how selected charged particle biology research gaps could be addressed using those facilities.

Sandia National Laboratories: Research: Laboratory Directed Research &

Science.gov Websites

; Technology Defense Systems & Assessments About Defense Systems & Assessments Program Areas Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

Preparing chimpanzees for laboratory research.

PubMed

Bloomsmith, Mollie A; Schapiro, Steven J; Strobert, Elizabeth A

2006-01-01

The chimpanzee is the only representative of the Great Apes that is extensively involved in biomedical research in primate laboratories. These apes are used as animal models in a variety of studies, including research on infectious disease, parasitic disease, pharmacokinetic studies, neuroscience, cognition, and behavior. Chimpanzees used in biomedical research in the United States reside largely in six specialized research and holding facilities, and most of the research with them is conducted at these sites. Given the relatively small population of chimpanzees and its importance to biomedical research, it is imperative that we carefully manage the care, production, and use of these animals in biomedical research studies. Selection criteria and preparation techniques are reviewed in this article in an effort to begin a discussion on best practices for choosing and handling chimpanzees participating in biomedical research. The use of routine health assessment information is described for subject selection, as are behavioral issues to be considered. Due to the relatively small number of chimpanzees available, issues related to experimental design and multiple uses of chimpanzees are discussed. Practices related to the transportation and acclimation of chimpanzees are described. Finally, behavioral conditioning procedures are discussed, including habituation, desensitization, and positive reinforcement training that have been applied to reduce animal distress and improve the quality of the science being conducted with chimpanzee subjects.

Air Force Research Laboratory

DTIC Science & Technology

2009-06-08

Air Force Research Laboratory 8 June 2009 Mr. Leo Marple Ai F R h L b t r orce esearc a ora ory Leo.Marple@wpafb.af.mil DISTRIBUTION STATEMENT A...TITLE AND SUBTITLE Air Force Research Laboratory 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER...5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Air Force Research Laboratory ,Wright

Savannah River Ecology Laboratory. Annual technical progress report of ecological research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, M.H.

1996-07-31

The Savannah River Ecology Laboratory (SREL) is a research unit of the University of Georgia (UGA). The overall mission of the Laboratory is to acquire and communicate knowledge of ecological processes and principles. SREL conducts basic and applied ecological research, as well as education and outreach programs, under a contract with the U.S. Department of Energy (DOE) at the Savannah River Site (SRS) near Aiken, South Carolina. Significant accomplishments were made during the past year in the areas of research, education and service. The Laboratory`s research mission was fulfilled with the publication of two books and 143 journal articles andmore » book chapters by faculty, technical and students, and visiting scientists. An additional three books and about 80 journal articles currently are in press. Faculty, technician and students presented 193 lectures, scientific presentations, and posters to colleges and universities, including minority institutions. Dr. J Vaun McArthur organized and conducted the Third Annual SREL Symposium on the Environment: New Concepts in Strewn Ecology: An Integrative Approach. Dr. Michael Newman conducted a 5-day course titled Quantitative Methods in Ecotoxicology, and Dr. Brian Teppen of The Advanced Analytical Center for Environmental Sciences (AACES) taught a 3-day short course titled Introduction to Molecular Modeling of Environmental Systems. Dr. I. Lehr Brisbin co-hosted a meeting of the Crocodile Special Interest Group. Dr. Rebecca Sharitz attended four symposia in Japan during May and June 1996 and conducted meetings of the Executive Committee and Board of the International Association for Ecology (ENTECOL).« less

Revealing all: misleading self-disclosure rates in laboratory-based online research.

PubMed

Callaghan, Diana E; Graff, Martin G; Davies, Joanne

2013-09-01

Laboratory-based experiments in online self-disclosure research may be inadvertently compromising the accuracy of research findings by influencing some of the factors known to affect self-disclosure behavior. Disclosure-orientated interviews conducted with 42 participants in the laboratory and in nonlaboratory settings revealed significantly greater breadth of self-disclosure in laboratory interviews, with message length and intimacy of content also strongly related. These findings suggest that a contrived online setting with a researcher presence may stimulate motivation for greater self-disclosure than would occur naturally in an online environment of an individual's choice. The implications of these findings are that researchers should consider the importance of experimental context and motivation in self-disclosure research.

Potato-related research at USDA-ARS laboratories in Washington and Idaho

USDA-ARS?s Scientific Manuscript database

Potato-related research currently being conducted at three USDA-ARS laboratories in Idaho and Washington is reviewed. Objectives of research programs at the Temperate Tree Fruit & Vegetable Research Unit (Wapato, WA), the Irrigated Agriculture Research and Extension Center (Prosser, WA), and the Sm...

Tree Topping Ceremony at NASA's Propulsion Research Laboratory

NASA Technical Reports Server (NTRS)

2003-01-01

A new, world-class laboratory for research into future space transportation technologies is under construction at the Marshall Space Flight Center (MSFC) in Huntsville, AL. The state-of-the-art Propulsion Research Laboratory will serve as a leading national resource for advanced space propulsion research. Its purpose is to conduct research that will lead to the creation and development of irnovative propulsion technologies for space exploration. The facility will be the epicenter of the effort to move the U.S. space program beyond the confines of conventional chemical propulsion into an era of greatly improved access to space and rapid transit throughout the solar system. The Laboratory is designed to accommodate researchers from across the United States, including scientists and engineers from NASA, the Department of Defense, the Department of Energy, universities, and industry. The facility, with 66,000 square feet of useable laboratory space, will feature a high degree of experimental capability. Its flexibility will allow it to address a broad range of propulsion technologies and concepts, such as plasma, electromagnetic, thermodynamic, and propellantless propulsion. An important area of emphasis will be development and utilization of advanced energy sources, including highly energetic chemical reactions, solar energy, and processes based on fission, fusion, and antimatter. The Propulsion Research Laboratory is vital for developing the advanced propulsion technologies needed to open up the space frontier, and will set the stage of research that could revolutionize space transportation for a broad range of applications. This photo depicts construction workers taking part in a tree topping ceremony as the the final height of the laboratory is framed. The ceremony is an old German custom of paying homage to the trees that gave their lives in preparation of the building site.

Freshwater findings, 1979-1982: research publications of the Environmental Research Laboratory, Duluth, Minnesota

DOE Office of Scientific and Technical Information (OSTI.GOV)

Highland, T.; Curtis, C.

1983-10-01

This report contains citations of publications for the years 1979-1982 on research conducted or supported by the Environmental Research Laboratory-Duluth. All published material has been organized into two major categories: (1) Journal Articles, Book Chapters, Proceedings, etc., and (2) EPA Research Reports. The report is organized by year with all journal articles, book chapters, proceedings, etc., for a given year appearing before the EPA research reports for the same year; within each category publications are listed alphabetically by author. Authors of the publications listed include ERL-Duluth laboratory staff members and scientists at universities, in industry, and at other facilities whomore » received research funding under the auspices of the Environmental Research Laboratory-Duluth. Limited quantities of reprints are available for those articles identified by ERL-Duluth reprint number in parentheses following the citation. These can be obtained by writing to: Librarian, ERL-Duluth, U.S. EPA, 6201 Congdon Boulevard, Duluth, MN 55804. EPA research reports can be obtained by writing to: National Technical Information Service, 5285 Port Royal Road, Springfield, VA 22151. All other articles are not available from ERL-Duluth or NTIS, but can be found in most major libraries.« less

Student research laboratory for optical engineering

NASA Astrophysics Data System (ADS)

Tolstoba, Nadezhda D.; Saitgalina, Azaliya; Abdula, Polina; Butova, Daria

2015-10-01

Student research laboratory for optical engineering is comfortable place for student's scientific and educational activity. The main ideas of laboratory, process of creation of laboratory and also activity of laboratory are described in this article. At ITMO University in 2013-2014 were formed a lot of research laboratories. SNLO is a student research (scientific) laboratory formed by the Department of Applied and computer optics of the University ITMO (Information Technologies of Mechanics and Optics). Activity of laboratory is career guidance of entrants and students in the field of optical engineering. Student research laboratory for optical engineering is a place where student can work in the interesting and entertaining scientific atmosphere.

Using the Human Systems Simulation Laboratory at Idaho National Laboratory for Safety Focused Research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Joe, Jeffrey .C; Boring, Ronald L.

Under the United States (U.S.) Department of Energy (DOE) Light Water Reactor Sustainability (LWRS) program, researchers at Idaho National Laboratory (INL) have been using the Human Systems Simulation Laboratory (HSSL) to conduct critical safety focused Human Factors research and development (R&D) for the nuclear industry. The LWRS program has the overall objective to develop the scientific basis to extend existing nuclear power plant (NPP) operating life beyond the current 60-year licensing period and to ensure their long-term reliability, productivity, safety, and security. One focus area for LWRS is the NPP main control room (MCR), because many of the instrumentation andmore » control (I&C) system technologies installed in the MCR, while highly reliable and safe, are now difficult to replace and are therefore limiting the operating life of the NPP. This paper describes how INL researchers use the HSSL to conduct Human Factors R&D on modernizing or upgrading these I&C systems in a step-wise manner, and how the HSSL has addressed a significant gap in how to upgrade systems and technologies that are built to last, and therefore require careful integration of analog and new advanced digital technologies.« less

THE EPA NATIONAL EXPOSURE RESEARCH LABORATORY CHILDREN'S PESTICIDE EXPOSURE MEASUREMENT PROGRAM

EPA Science Inventory

The U.S. EPA's National Exposure Research Laboratory (NERL) conducts research in support of the Food Quality Protection Act (FQPA) of 1996. FQPA requires that children's risks to pesticide exposures be considered during the tolerance-setting process. The Act requires exposure...

THE EPA NATIONAL EXPOSURE RESEARCH LABORATORY CHILDREN'S PESTICIDE EXPOSURE MEASUREMENT PROGRAM

EPA Science Inventory

The U.S. Environmental Protection Agency (EPA) National Exposure Research Laboratory (NERL) is performing research in support of the Food Quality Protection Act (FQPA) of 1996. This act requires that pesticide exposure assessments to be conducted for all potential sources, rou...

About the Frederick National Laboratory for Cancer Research | Frederick National Laboratory for Cancer Research

Cancer.gov

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and currently operated by Leidos Biomedical Research, Inc. The laboratory addresses some of the most urge

Cookstove Laboratory Research - Fiscal Year 2016 Report ...

EPA Pesticide Factsheets

This report provides an overview of the work conducted by the EPA cookstove laboratory research team in Fiscal Year 2016. The report describes research and activities including (1) ISO standards development, (2) capacity building for international testing and knowledge centers, (3) laboratory assessments of cookstove systems, (4) journal publications, and (5) cookstove events. The U.S. Environmental Protection Agency’s (EPA’s) cookstove laboratory research program was first developed to assist the EPA-led Partnership for Clean Indoor Air and is now part of the U.S. Government’s commitment to the Global Alliance for Clean Cookstoves (the Alliance). Goals of the program are to: (1) support the development of testing protocols and standards for cookstoves through ISO (International Organization for Standardization) TC (Technical Committee) 285: Clean Cookstoves and Clean Cooking Solutions, (2) support the development of international Regional Testing and Knowledge Centers (many sponsored by the Alliance) for scientifically evaluating and certifying cookstoves to international standards, and (3) provide an independent source of data to Alliance partners. This work supports EPA’s mission to protect human health and the environment. Household air pollution, mainly from solid-fuel cookstoves in the developing world, is estimated to cause approximately 4 million premature deaths per year, and emissions of black carbon and other pollutants from cookstoves aff

Catalog of Research Abstracts, 1993: Partnership opportunities at Lawrence Berkeley Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-09-01

The 1993 edition of Lawrence Berkeley Laboratory`s Catalog of Research Abstracts is a comprehensive listing of ongoing research projects in LBL`s ten research divisions. Lawrence Berkeley Laboratory (LBL) is a major multi-program national laboratory managed by the University of California for the US Department of Energy (DOE). LBL has more than 3000 employees, including over 1000 scientists and engineers. With an annual budget of approximately $250 million, LBL conducts a wide range of research activities, many that address the long-term needs of American industry and have the potential for a positive impact on US competitiveness. LBL actively seeks to sharemore » its expertise with the private sector to increase US competitiveness in world markets. LBL has transferable expertise in conservation and renewable energy, environmental remediation, materials sciences, computing sciences, and biotechnology, which includes fundamental genetic research and nuclear medicine. This catalog gives an excellent overview of LBL`s expertise, and is a good resource for those seeking partnerships with national laboratories. Such partnerships allow private enterprise access to the exceptional scientific and engineering capabilities of the federal laboratory systems. Such arrangements also leverage the research and development resources of the private partner. Most importantly, they are a means of accessing the cutting-edge technologies and innovations being discovered every day in our federal laboratories.« less

Lumber drying and heat sterilization research at the U.S. Forest Products Laboratory

Treesearch

William T. Simpson

2002-01-01

The Forest Products Laboratory (FPL) has a long history of research and technology transfer in lumber drying. Many of the dry kiln schedules used in industry today were developed by the staff of the Laboratory, and for many years the Laboratory conducted a kiln drying short course for training dry kiln operators. The purpose of this report is to describe the Laboratory...

POLLUTION PREVENTION FOR CLEANER AIR: EPA'S AIR AND ENERGY ENGINEERING RESEARCH LABORATORY

EPA Science Inventory

The article discusses the role of EPA's Air and Energy Engineering Research Laboratory (AEERL) in pollution prevention research for cleaner air. For more than 20 years, AEERL has been conducting research to identify control approaches for the pollutants and sources which contribu...

Laboratory performance of sweat conductivity for the screening of cystic fibrosis.

PubMed

Greaves, Ronda F; Jolly, Lisa; Massie, John; Scott, Sue; Wiley, Veronica C; Metz, Michael P; Mackay, Richard J

2018-03-28

There are several complementary English-language guidelines for the performance of the sweat chloride test. These guidelines also incorporate information for the collection of conductivity samples. However, recommendations for the measurement and reporting of sweat conductivity are less clear than for sweat chloride. The aim of the study was to develop an understanding of the testing and reporting practices of sweat conductivity in Australasian laboratories. A survey specifically directed at conductivity testing was sent to the 12 laboratories registered with the Royal College of Pathologists of Australasia Quality Assurance Programs. Nine (75%) laboratories participated in the survey, seven of whom used Wescor Macroduct® for collecting sweat and the Wescor SWEAT·CHEK™ for conductivity testing, and the remaining two used the Wescor Nanoduct®. There was considerable variation in frequency and staffing for this test. Likewise, criteria about which patients it was inappropriate to test, definitions of adequate collection sweat rate, cutoffs and actions recommended on the basis of the result showed variations between laboratories. Variations in sweat conductivity testing and reporting reflect many of the same issues that were revealed in sweat chloride test audits and have the potential to lead to uncertainty about the result and the proper action in response to the result. We recommend that sweat testing guidelines should include clearer statements about the use of sweat conductivity.

Aeroservoelastic and Structural Dynamics Research on Smart Structures Conducted at NASA Langley Research Center

NASA Technical Reports Server (NTRS)

McGowan, Anna-Maria Rivas; Wilkie, W. Keats; Moses, Robert W.; Lake, Renee C.; Florance, Jennifer Pinkerton; Wieseman, Carol D.; Reaves, Mercedes C.; Taleghani, Barmac K.; Mirick, Paul H.; Wilbur, Mathew L.

1997-01-01

An overview of smart structures research currently underway at the NASA Langley Research Center in the areas of aeroservoelasticity and structural dynamics is presented. Analytical and experimental results, plans, potential technology pay-offs, and challenges are discussed. The goal of this research is to develop the enabling technologies to actively and passively control aircraft and rotorcraft vibration and loads using smart devices. These enabling technologies and related research efforts include developing experimentally-validated finite element and aeroservoelastic modeling techniques; conducting bench experimental tests to assess feasibility and understand system trade-offs; and conducting large-scale wind tunnel tests to demonstrate system performance. The key aeroservoelastic applications of this research include: active twist control of rotor blades using interdigitated electrode piezoelectric composites and active control of flutter, and gust and buffeting responses using discrete piezoelectric patches. In addition, NASA Langley is an active participant in the DARPA/Air Force Research Laboratory/NASA/Northrop Grumman Smart Wing program which is assessing aerodynamic performance benefits using smart materials.

Escambia Experimental Forest: A Living Laboratory for Long Term Longleaf Pine Research

Treesearch

Charles K. McMahon

2000-01-01

Experimental Forests have been used for many years by research organizations as "living laboratories" where long-term research studies can be conducted. For forestry and related natural resources research, "long term" can often mean decades of continuous study before meaningful results can be obtained. The Escambia Experimental Forest was...

US Naval Research Laboratory's Current Space Photovoltaic Experiemtns

NASA Astrophysics Data System (ADS)

Jenkins, Phillip; Walters, Robert; Messenger, Scott; Krasowski, Michael

2008-09-01

The US Naval Research Laboratory (NRL) has a rich history conducting space photovoltaic (PV) experiments starting with Vanguard I, the first solar powered satellite in 1958. Today, NRL in collaboration with the NASA Glenn Research Center, is engaged in three flight experiments demonstrating a wide range of PV technologies in both LEO and HEO orbits. The Forward Technology Solar Cell Experiment (FTSCE)[1], part of the 5th Materials on the International Space Station Experiment (MISSE-5), flew for 13 months on the International Space Station in 2005-2006. The FTSCE provided in-situ I-V monitoring of advanced III-V multi-junction cells and laboratory prototypes of thin film and other next generation technologies. Two experiments under development will provide more opportunities to demonstrate advanced solar cells and characterization electronics that are easily integrated on a wide variety of spacecraft bus architectures.

2015 Fermilab Laboratory Directed Research & Development Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wester, W.

2016-05-26

The Fermi National Accelerator Laboratory (FNAL) is conducting a Laboratory Directed Research and Development (LDRD) program. Fiscal year 2015 represents the first full year of LDRD at Fermilab and includes seven projects approved mid-year in FY14 and six projects approved in FY15. One of the seven original projects has been completed just after the beginning of FY15. The implementation of LDRD at Fermilab is captured in the approved Fermilab 2015 LDRD Annual Program Plan. In FY15, the LDRD program represents 0.64% of Laboratory funding. The scope of the LDRD program at Fermilab will be established over the next couple ofmore » years where a portfolio of about 20 on-going projects representing approximately between 1% and 1.5% of the Laboratory funding is anticipated. This Annual Report focuses on the status of the current projects and provides an overview of the current status of LDRD at Fermilab.« less

Redefining Authentic Research Experiences in Introductory Biology Laboratories and Barriers to Their Implementation

PubMed Central

Spell, Rachelle M.; Guinan, Judith A.; Miller, Kristen R.; Beck, Christopher W.

2014-01-01

Incorporating authentic research experiences in introductory biology laboratory classes would greatly expand the number of students exposed to the excitement of discovery and the rigor of the scientific process. However, the essential components of an authentic research experience and the barriers to their implementation in laboratory classes are poorly defined. To guide future reform efforts in this area, we conducted a national survey of biology faculty members to determine 1) their definitions of authentic research experiences in laboratory classes, 2) the extent of authentic research experiences currently experienced in their laboratory classes, and 3) the barriers that prevent incorporation of authentic research experiences into these classes. Strikingly, the definitions of authentic research experiences differ among faculty members and tend to emphasize either the scientific process or the discovery of previously unknown data. The low level of authentic research experiences in introductory biology labs suggests that more development and support is needed to increase undergraduate exposure to research experiences. Faculty members did not cite several barriers commonly assumed to impair pedagogical reform; however, their responses suggest that expanded support for development of research experiences in laboratory classes could address the most common barrier. PMID:24591509

Redefining authentic research experiences in introductory biology laboratories and barriers to their implementation.

PubMed

Spell, Rachelle M; Guinan, Judith A; Miller, Kristen R; Beck, Christopher W

2014-01-01

Incorporating authentic research experiences in introductory biology laboratory classes would greatly expand the number of students exposed to the excitement of discovery and the rigor of the scientific process. However, the essential components of an authentic research experience and the barriers to their implementation in laboratory classes are poorly defined. To guide future reform efforts in this area, we conducted a national survey of biology faculty members to determine 1) their definitions of authentic research experiences in laboratory classes, 2) the extent of authentic research experiences currently experienced in their laboratory classes, and 3) the barriers that prevent incorporation of authentic research experiences into these classes. Strikingly, the definitions of authentic research experiences differ among faculty members and tend to emphasize either the scientific process or the discovery of previously unknown data. The low level of authentic research experiences in introductory biology labs suggests that more development and support is needed to increase undergraduate exposure to research experiences. Faculty members did not cite several barriers commonly assumed to impair pedagogical reform; however, their responses suggest that expanded support for development of research experiences in laboratory classes could address the most common barrier.

Laboratory Animal Facilities. Laboratory Design Notes.

ERIC Educational Resources Information Center

Jonas, Albert M.

1965-01-01

Design of laboratory animal facilities must be functional. Accordingly, the designer should be aware of the complex nature of animal research and specifically the type of animal research which will be conducted in a new facility. The building of animal-care facilities in research institutions requires special knowledge in laboratory animal…

Space Station Freedom: a unique laboratory for gravitational biology research

NASA Technical Reports Server (NTRS)

Phillips, R. W.; Cowing, K. L.

1993-01-01

The advent of Space Station Freedom (SSF) will provide a permanent laboratory in space with unparalleled opportunities to perform biological research. As with any spacecraft there will also be limitations. It is our intent to describe this space laboratory and present a picture of how scientists will conduct research in this unique environment we call space. SSF is an international venture which will continue to serve as a model for other peaceful international efforts. It is hoped that as the human race moves out from this planet back to the moon and then on to Mars that SSF can serve as a successful example of how things can and should be done.

Initiation of Research at the Aircraft Engine Research Laboratory

NASA Image and Video Library

1942-05-21

A group of National Advisory Committee for Aeronautics (NACA) officials and local dignitaries were on hand on May 8, 1942, to witness the Initiation of Research at the NACA's new Aircraft Engine Research Laboratory in Cleveland, Ohio. The group in this photograph was in the control room of the laboratory's first test facility, the Engine Propeller Research Building. The NACA press release that day noted, "First actual research activities in what is to be the largest aircraft engine research laboratory in the world was begun today at the National Advisory Committee for Aeronautics laboratory at the Cleveland Municipal Airport.” The ceremony, however, was largely symbolic since most of the laboratory was still under construction. Dr. George W. Lewis, the NACA's Director of Aeronautical Research, and John F. Victory, NACA Secretary, are at the controls in this photograph. Airport Manager John Berry, former City Manager William Hopkins, NACA Assistant Secretary Ed Chamberlain, Langley Engineer-in-Charge Henry Reid, Executive Engineer Carlton Kemper, and Construction Manager Raymond Sharp are also present. The propeller building contained two torque stands to test complete engines at ambient conditions. The facility was primarily used at the time to study engine lubrication and cooling systems for World War II aircraft, which were required to perform at higher altitudes and longer ranges than previous generations.

Responsible Conduct of Research: Not Just for Researchers

ERIC Educational Resources Information Center

Schaller-Demers, Debra S.

2015-01-01

Every research institution employs administrative staff who support the research community on a daily basis. Whether in a central office, department, clinic or laboratory, these people may not be aware of the important role they play in safe-guarding the integrity of the research enterprise. Frequently, research administrators are forced to face…

Laboratory Directed Research and Development Program Activities for FY 2007.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Newman,L.

2007-12-31

Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal year 2007 budget was $515 million. There are about 2,600 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annuallymore » in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development', April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. In accordance this is our Annual Report in which we describe the Purpose, Approach, Technical Progress and Results, and Specific Accomplishments of all LDRD projects that received funding during Fiscal Year 2007. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new 'fundable' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research 'which could lead to new programs, projects, and directions' for the Laboratory. We explicitly indicate that research conducted under the LDRD Program should be highly innovative, and an element of high risk as to success is acceptable. In the solicitation for new proposals for Fiscal Year 2007 we especially requested innovative new projects in support of RHIC and the Light Source and

The value-added laboratory: an opportunity to merge research and service objectives.

PubMed

McDonald, J M

1997-01-01

The changing health-care environment is creating a new opportunities for laboratory medicine professionals that correspond with the new health services research agendas. Proving cost-effectiveness and conducting outcomes assessment are becoming vital functions of laboratories in this era of managed care. Laboratorians must take advantage of the resulting opportunities to show how they add value and medical relevance to the health-care delivery system.

Bridging the Gap between Instructional and Research Laboratories: Teaching Data Analysis Software Skills through the Manipulation of Original Research Data

ERIC Educational Resources Information Center

Hansen, Sarah J. R.; Zhu, Jieling; Karch, Jessica M.; Sorrento, Cristina M.; Ulichny, Joseph C.; Kaufman, Laura J.

2016-01-01

The gap between graduate research and introductory undergraduate teaching laboratories is often wide, but the development of teaching activities rooted within the research environment offers an opportunity for undergraduate students to have first-hand experience with research currently being conducted and for graduate students to develop…

How Work Positions Affect the Research Activity and Information Behaviour of Laboratory Scientists in the Research Lifecycle: Applying Activity Theory

ERIC Educational Resources Information Center

Kwon, Nahyun

2017-01-01

Introduction: This study was conducted to investigate the characteristics of research and information activities of laboratory scientists in different work positions throughout a research lifecycle. Activity theory was applied as the conceptual and analytical framework. Method: Taking a qualitative research approach, in-depth interviews and field…

Conducting Human Research

DTIC Science & Technology

2009-08-05

Socio-cultural data acquisition, extraction, and management.??? First the idea of a theoretical framework will be very briefly discussed as well as...SUBJECT TERMS human behavior, theoretical framework , hypothesis development, experimental design, ethical research, statistical power, human laboratory...who throw rocks? • How can we make them stay too far away to throw rocks? UNCLASSIFIED – Approved for Public Release Theoretical Framework / Conceptual

Aeroservoelastic and Structural Dynamics Research on Smart Structures Conducted at NASA Langley Research Center

NASA Technical Reports Server (NTRS)

McGowan, Anna-Maria Rivas; Wilkie, W. Keats; Moses, Robert W.; Lake, Renee C.; Florance, Jennifer Pinkerton; Wieseman, Carol D.; Reaves, Mercedes C.; Taleghani, Barmac K.; Mirick, Paul H.; Wilbur, Matthew L.

1998-01-01

An overview of smart structures research currently underway at the NASA Langley Research Center in the areas of aeroservoelasticity and structural dynamics is presented. Analytical and experimental results, plans, potential technology pay-offs, and challenges are discussed. The goal of this research is to develop the enabling technologies to actively and passively control aircraft and rotorcraft vibration and loads using smart devices. These enabling technologies and related research efforts include developing experimentally-validated finite element and aeroservoelastic modeling techniques; conducting bench experimental tests to assess feasibility and understand system trade-offs; and conducting large-scale wind- tunnel tests to demonstrate system performance. The key aeroservoelastic applications of this research include: active twist control of rotor blades using interdigitated electrode piezoelectric composites and active control of flutter, and gust and buffeting responses using discrete piezoelectric patches. In addition, NASA Langley is an active participant in the DARPA/ Air Force Research Laboratory/ NASA/ Northrop Grumman Smart Wing program which is assessing aerodynamic performance benefits using smart materials. Keywords: aeroelasticity, smart structures, piezoelectric actuators, active fiber composites, rotorcraft, buffet load alleviation, individual blade control, aeroservoelasticity, shape memory alloys, damping augmentation, piezoelectric power consumption

Bringing ayahuasca to the clinical research laboratory.

PubMed

Riba, Jordi; Barbanoj, Manel J

2005-06-01

Since the winter of 1999, the authors and their research team have been conducting clinical studies involving the administration of ayahuasca to healthy volunteers. The rationale for conducting this kind of research is twofold. First, the growing interest of many individuals for traditional indigenous practices involving the ingestion of natural psychotropic drugs such as ayahuasca demands the systematic study of their pharmacological profiles in the target species, i.e., human beings. The complex nature of ayahuasca brews combining a large number of pharmacologically active compounds requires that research be carried out to establish the safety and overall pharmacological profile of these products. Second, the authors believe that the study of psychedelics in general calls for renewed attention. Although the molecular and electrophysiological level effects of these drugs are relatively well characterized, current knowledge of the mechanisms by which these compounds modify the higher order cognitive processes in the way they do is still incomplete, to say the least. The present article describes the development of the research effort carried out at the Autonomous University of Barcelona, commenting on several methodological aspects and reviewing the basic clinical findings. It also describes the research currently underway in our laboratory, and briefly comments on two new studies we plan to undertake in order to further our knowledge of the pharmacology of ayahuasca.

Air Force Research Laboratory Preparation for Year 2000.

DTIC Science & Technology

1998-10-05

Air Force Research Laboratory , Phillips Research Site , Kirkland Air Force Base, New...Pentagon, Washington, D.C. 20301-1900. The identity of each writer and caller is fully protected. Acronym AFRL Air Force Research Laboratory INSPECTOR...completion of the implementation phase was May 31, 1999. Air Force Research Laboratory . The Air Force Research

Thirty-Two Years of Forest Service Research at the Southern Forest Fire Laboratory in Macon, GA

Treesearch

USDA Forest Service

1991-01-01

When completed in 1959, the Southern Forest Fire Laboratory was the world?s first devoted entirely to the study of forest fires, Since then the scientists at the Laboratory have: 1) performed basic and applied research on critical fire problems of national interest, 2) conducted special regional research on fire problems peculiar to the 13 Southern States, and 3)...

Helical Explosive Flux Compression Generator Research at the Air Force Research Laboratory

DTIC Science & Technology

1999-06-01

Air Force Research Laboratory Kirtland AFB...ORGANIZATION NAME(S) AND ADDRESS(ES) Directed Energy Directorate, Air Force Research Laboratory Kirtland AFB, NM 8. PERFORMING ORGANIZATION REPORT...in support of the Air Force Research Laboratory ( AFRL ) explosive pulsed power program. These include circuit codes such as Microcap and

Network Science Research Laboratory (NSRL) Discrete Event Toolkit

DTIC Science & Technology

2016-01-01

ARL-TR-7579 ● JAN 2016 US Army Research Laboratory Network Science Research Laboratory (NSRL) Discrete Event Toolkit by...Laboratory (NSRL) Discrete Event Toolkit by Theron Trout and Andrew J Toth Computational and Information Sciences Directorate, ARL...Research Laboratory (NSRL) Discrete Event Toolkit 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Theron Trout

Integrating Responsible Conduct of Research Education into Undergraduate Biochemistry and Molecular Biology Laboratory Curricula

ERIC Educational Resources Information Center

Hendrickson, Tamara L.

2015-01-01

Recently, a requirement for directed responsible conduct in research (RCR) education has become a priority in the United States and elsewhere. In the US, both the National Institutes of Health and the National Science Foundation require RCR education for all students who are financially supported by federal awards. The guidelines produced by these…

Laboratory-based electrical conductivity at Martian mantle conditions

NASA Astrophysics Data System (ADS)

Verhoeven, Olivier; Vacher, Pierre

2016-12-01

Information on temperature and composition of planetary mantles can be obtained from electrical conductivity profiles derived from induced magnetic field analysis. This requires a modeling of the conductivity for each mineral phase at conditions relevant to planetary interiors. Interpretation of iron-rich Martian mantle conductivity profile therefore requires a careful modeling of the conductivity of iron-bearing minerals. In this paper, we show that conduction mechanism called small polaron is the dominant conduction mechanism at temperature, water and iron content conditions relevant to Mars mantle. We then review the different measurements performed on mineral phases with various iron content. We show that, for all measurements of mineral conductivity reported so far, the effect of iron content on the activation energy governing the exponential decrease in the Arrhenius law can be modeled as the cubic square root of the iron content. We recast all laboratory results on a common generalized Arrhenius law for iron-bearing minerals, anchored on Earth's mantle values. We then use this modeling to compute a new synthetic profile of Martian mantle electrical conductivity. This new profile matches perfectly, in the depth range [100,1000] km, the electrical conductivity profile recently derived from the study of Mars Global Surveyor magnetic field measurements.

Human Laboratory Paradigms in Alcohol Research

PubMed Central

Plebani, Jennifer G.; Ray, Lara A.; Morean, Meghan E.; Corbin, William R.; Mackillop, James; Amlung, Michael; King, Andrea C.

2014-01-01

Human laboratory studies have a long and rich history in the field of alcoholism. Human laboratory studies have allowed for advances in alcohol research in a variety of ways, including elucidating of the neurobehavioral mechanisms of risk, identifying phenotypically distinct sub-types of alcohol users, investigating of candidate genes underlying experimental phenotypes for alcoholism, and testing mechanisms of action of alcoholism pharmacotherapies on clinically-relevant translational phenotypes, such as persons exhibiting positive-like alcohol effects or alcohol craving. Importantly, the field of human laboratory studies in addiction has progressed rapidly over the past decade and has built upon earlier findings of alcohol's neuropharmacological effects to advancing translational research on alcoholism etiology and treatment. To that end, the new generation of human laboratory studies has focused on applying new methodologies, further refining alcoholism phenotypes, and translating these findings to studies of alcoholism genetics, medication development, and pharmacogenetics. The combination of experimental laboratory approaches with recent developments in neuroscience and pharmacology has been particularly fruitful in furthering our understanding of the impact of individual differences in alcoholism risk and in treatment response. This review of the literature focuses on human laboratory studies of subjective intoxication, alcohol craving, anxiety, and behavioral economics. Each section discusses opportunities for phenotype refinement under laboratory conditions, as well as its application to translational science of alcoholism. A summary and recommendations for future research are also provided. PMID:22309888

Battelle's Marine Research Laboratory, Sequim

DOE Office of Scientific and Technical Information (OSTI.GOV)

Becker, C.D.; Strand, J.A.

Scientists at Battelle's Marine Research Laboratory (MRL) in Sequim, Washington study the effect of human activities on marine ecosystems, with emphasis on near shore and estuarine environments. The laboratory provides research and development assistance to industry and government agencies engaged in management of marine technologies, operation of coastal power utilities, protection of the marine environment, and related areas. This paper outlines and discusses the functions of Battelle's MRL, it's history, it's unique features, it's areas of expertise, it's current programs, and it's cooperating agencies.

Pacific Northwest Laboratory annual report for 1993 to the DOE Office of Energy Research. Part 1: Biomedical Sciences

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lumetta, C.C.; Park, J.F.

1994-03-01

This report summarizes FY 1993 progress in biological and general life sciences research programs conducted for the Department of Energy`s Office of Health and Environmental REsearch (OHER) at Pacific Northwest Laboratory (PNL). This research provides knowledge of fundamental principles necessary to identify, understand, and anticipate the long-term health consequences of exposure to energy-related radiation and chemicals. The Biological Research section contains reports of studies using laboratory animals, in vitro cell systems, and molecular biological systems. This research includes studies of the impact of radiation, radionuclides, and chemicals on biological responses at all levels of biological organization. The General Life Sciencesmore » Research section reports research conducted for the OHER human genome program.« less

Conducting Rapid, Relevant Research

PubMed Central

Glasgow, Russell E.; Kessler, Rodger S.; Ory, Marcia G.; Roby, Dylan; Gorin, Sherri Sheinfeld; Krist, Alex

2015-01-01

The lengthy and uncertain translation of research into clinical practice is well documented. Much of the current “gold standard” clinical research is slow, expensive, and lacks perceived relevance for practitioners and decision makers. In contrast, we summarize experiences conducting the My Own Health Report (MOHR) project to collect and address patient reported measures using principles of rapid, relevant pragmatic research. The methods used for rapid design and fielding of the MOHR project to improve attention to health behaviors and mental health are detailed. Within the multisite, pragmatic, implementation–focused MOHR study, we describe the four phases of the research and the key decisions made and actions taken within each. We provide concrete examples of how relevant research can be conducted transparently to rapidly provide information to practitioners. Data were collected and analyzed in 2013. The multisite (seven research centers partnered with 18 clinics) cluster randomized pragmatic delayed intervention trial was conducted in less than 18 months from receipt of funding applications to completion of data collection. Phases that were especially accelerated included funding and review, and recruitment and implementation. Conducting complex studies rapidly and efficiently is a realistic goal. Key lessons learned for prevention research include: use of existing research networks; use of web-based assessment/feedback tools that are tailored to fit local needs; engaging relevant stakeholders early on and throughout the process to minimize need for redesign; and making pragmatic decisions that balance internal and external validity concerns rather than waiting for perfect solutions. PMID:24953520

Ethical and methodological standards for laboratory and medical biological rhythm research.

PubMed

Portaluppi, Francesco; Touitou, Yvan; Smolensky, Michael H

2008-11-01

The main objectives of this article are to update the ethical standards for the conduct of human and animal biological rhythm research and recommend essential elements for quality chronobiological research information, which should be especially useful for new investigators of the rhythms of life. A secondary objective is to provide for those with an interest in the results of chronobiology investigations, but who might be unfamiliar with the field, an introduction to the basic methods and standards of biological rhythm research and time series data analysis. The journal and its editors endorse compliance of all investigators to the principles of the Declaration of Helsinki of the World Medical Association, which relate to the conduct of ethical research on human beings, and the Guide for the Care and Use of Laboratory Animals of the Institute for Laboratory Animal Research of the National Research Council, which relate to the conduct of ethical research on laboratory and other animals. The editors and the readers of the journal expect the authors of submitted manuscripts to have adhered to the ethical standards dictated by local, national, and international laws and regulations in the conduct of investigations and to be unbiased and accurate in reporting never-before-published research findings. Authors of scientific papers are required to disclose all potential conflicts of interest, particularly when the research is funded in part or in full by the medical and pharmaceutical industry, when the authors are stock-holders of the company that manufactures or markets the products under study, or when the authors are a recent or current paid consultant to the involved company. It is the responsibility of the authors of submitted manuscripts to clearly present sufficient detail about the synchronizer schedule of the studied subjects (i.e., the sleep-wake schedule, ambient light-dark cycle, intensity and spectrum of ambient light exposure, seasons when the research was

Comparison of microbiological diagnosis of urinary tract infection in young children by routine health service laboratories and a research laboratory: Diagnostic cohort study.

PubMed

Birnie, Kate; Hay, Alastair D; Wootton, Mandy; Howe, Robin; MacGowan, Alasdair; Whiting, Penny; Lawton, Michael; Delaney, Brendan; Downing, Harriet; Dudley, Jan; Hollingworth, William; Lisles, Catherine; Little, Paul; O'Brien, Kathryn; Pickles, Timothy; Rumsby, Kate; Thomas-Jones, Emma; Van der Voort, Judith; Waldron, Cherry-Ann; Harman, Kim; Hood, Kerenza; Butler, Christopher C; Sterne, Jonathan A C

2017-01-01

To compare the validity of diagnosis of urinary tract infection (UTI) through urine culture between samples processed in routine health service laboratories and those processed in a research laboratory. We conducted a prospective diagnostic cohort study in 4808 acutely ill children aged <5 years attending UK primary health care. UTI, defined as pure/predominant growth ≥105 CFU/mL of a uropathogen (the reference standard), was diagnosed at routine health service laboratories and a central research laboratory by culture of urine samples. We calculated areas under the receiver-operator curve (AUC) for UTI predicted by pre-specified symptoms, signs and dipstick test results (the "index test"), separately according to whether samples were obtained by clean catch or nappy (diaper) pads. 251 (5.2%) and 88 (1.8%) children were classified as UTI positive by health service and research laboratories respectively. Agreement between laboratories was moderate (kappa = 0.36; 95% confidence interval [CI] 0.29, 0.43), and better for clean catch (0.54; 0.45, 0.63) than nappy pad samples (0.20; 0.12, 0.28). In clean catch samples, the AUC was lower for health service laboratories (AUC = 0.75; 95% CI 0.69, 0.80) than the research laboratory (0.86; 0.79, 0.92). Values of AUC were lower in nappy pad samples (0.65 [0.61, 0.70] and 0.79 [0.70, 0.88] for health service and research laboratory positivity, respectively) than clean catch samples. The agreement of microbiological diagnosis of UTI comparing routine health service laboratories with a research laboratory was moderate for clean catch samples and poor for nappy pad samples and reliability is lower for nappy pad than for clean catch samples. Positive results from the research laboratory appear more likely to reflect real UTIs than those from routine health service laboratories, many of which (particularly from nappy pad samples) could be due to contamination. Health service laboratories should consider adopting procedures used in

Comparison of microbiological diagnosis of urinary tract infection in young children by routine health service laboratories and a research laboratory: Diagnostic cohort study

PubMed Central

Birnie, Kate; Hay, Alastair D.; Wootton, Mandy; Howe, Robin; MacGowan, Alasdair; Whiting, Penny; Lawton, Michael; Delaney, Brendan; Downing, Harriet; Dudley, Jan; Hollingworth, William; Lisles, Catherine; Little, Paul; O’Brien, Kathryn; Pickles, Timothy; Rumsby, Kate; Thomas-Jones, Emma; Van der Voort, Judith; Waldron, Cherry-Ann; Harman, Kim; Hood, Kerenza; Butler, Christopher C.; Sterne, Jonathan A. C.

2017-01-01

Objectives To compare the validity of diagnosis of urinary tract infection (UTI) through urine culture between samples processed in routine health service laboratories and those processed in a research laboratory. Population and methods We conducted a prospective diagnostic cohort study in 4808 acutely ill children aged <5 years attending UK primary health care. UTI, defined as pure/predominant growth ≥105 CFU/mL of a uropathogen (the reference standard), was diagnosed at routine health service laboratories and a central research laboratory by culture of urine samples. We calculated areas under the receiver-operator curve (AUC) for UTI predicted by pre-specified symptoms, signs and dipstick test results (the “index test”), separately according to whether samples were obtained by clean catch or nappy (diaper) pads. Results 251 (5.2%) and 88 (1.8%) children were classified as UTI positive by health service and research laboratories respectively. Agreement between laboratories was moderate (kappa = 0.36; 95% confidence interval [CI] 0.29, 0.43), and better for clean catch (0.54; 0.45, 0.63) than nappy pad samples (0.20; 0.12, 0.28). In clean catch samples, the AUC was lower for health service laboratories (AUC = 0.75; 95% CI 0.69, 0.80) than the research laboratory (0.86; 0.79, 0.92). Values of AUC were lower in nappy pad samples (0.65 [0.61, 0.70] and 0.79 [0.70, 0.88] for health service and research laboratory positivity, respectively) than clean catch samples. Conclusions The agreement of microbiological diagnosis of UTI comparing routine health service laboratories with a research laboratory was moderate for clean catch samples and poor for nappy pad samples and reliability is lower for nappy pad than for clean catch samples. Positive results from the research laboratory appear more likely to reflect real UTIs than those from routine health service laboratories, many of which (particularly from nappy pad samples) could be due to contamination. Health service

Experiences of mentors training underrepresented undergraduates in the research laboratory.

PubMed

Prunuske, Amy J; Wilson, Janelle; Walls, Melissa; Clarke, Benjamin

2013-01-01

Successfully recruiting students from underrepresented groups to pursue biomedical science research careers continues to be a challenge. Early exposure to scientific research is often cited as a powerful means to attract research scholars with the research mentor being critical in facilitating the development of an individual's science identity and career; however, most mentors in the biological sciences have had little formal training in working with research mentees. To better understand mentors' experiences working with undergraduates in the laboratory, we conducted semistructured interviews with 15 research mentors at a public university in the Midwest. The interviewed mentors were part of a program designed to increase the number of American Indians pursuing biomedical/biobehavioral research careers and represented a broad array of perspectives, including equal representation of male and female mentors, mentors from underrepresented groups, mentors at different levels of their careers, and mentors from undergraduate and professional school departments. The mentors identified benefits and challenges in being an effective mentor. We also explored what the term underrepresented means to the mentors and discovered that most of the mentors had an incomplete understanding about how differences in culture could contribute to underrepresented students' experience in the laboratory. Our interviews identify issues relevant to designing programs and courses focused on undergraduate student research.

Experiences of Mentors Training Underrepresented Undergraduates in the Research Laboratory

PubMed Central

Prunuske, Amy J.; Wilson, Janelle; Walls, Melissa; Clarke, Benjamin

2013-01-01

Successfully recruiting students from underrepresented groups to pursue biomedical science research careers continues to be a challenge. Early exposure to scientific research is often cited as a powerful means to attract research scholars with the research mentor being critical in facilitating the development of an individual's science identity and career; however, most mentors in the biological sciences have had little formal training in working with research mentees. To better understand mentors’ experiences working with undergraduates in the laboratory, we conducted semistructured interviews with 15 research mentors at a public university in the Midwest. The interviewed mentors were part of a program designed to increase the number of American Indians pursuing biomedical/biobehavioral research careers and represented a broad array of perspectives, including equal representation of male and female mentors, mentors from underrepresented groups, mentors at different levels of their careers, and mentors from undergraduate and professional school departments. The mentors identified benefits and challenges in being an effective mentor. We also explored what the term underrepresented means to the mentors and discovered that most of the mentors had an incomplete understanding about how differences in culture could contribute to underrepresented students’ experience in the laboratory. Our interviews identify issues relevant to designing programs and courses focused on undergraduate student research. PMID:24006389

41 CFR 101-25.109 - Laboratory and research equipment.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Laboratory and research...-General Policies § 101-25.109 Laboratory and research equipment. (a) This section prescribes controls for use by Federal agencies in managing laboratory and research equipment in Federal laboratories...

41 CFR 101-25.109 - Laboratory and research equipment.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 41 Public Contracts and Property Management 2 2014-07-01 2012-07-01 true Laboratory and research...-General Policies § 101-25.109 Laboratory and research equipment. (a) This section prescribes controls for use by Federal agencies in managing laboratory and research equipment in Federal laboratories...

41 CFR 101-25.109 - Laboratory and research equipment.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 41 Public Contracts and Property Management 2 2012-07-01 2012-07-01 false Laboratory and research...-General Policies § 101-25.109 Laboratory and research equipment. (a) This section prescribes controls for use by Federal agencies in managing laboratory and research equipment in Federal laboratories...

Fuels and Lubrication Researcher at the Aircraft Engine Research Laboratory

NASA Image and Video Library

1943-08-21

A researcher at the National Advisory Committee for Aeronautics (NACA) Aircraft Engine Research Laboratory studies the fuel ignition process. Improved fuels and lubrication was an area of particular emphasis at the laboratory during World War II. The military sought to use existing types of piston engines in order to get large numbers of aircraft into the air as quickly as possible. To accomplish its goals, however, the military needed to increase the performance of these engines without having to wait for new models or extensive redesigns. The Aircraft Engine Research Laboratory was called on to lead this effort. The use of superchargers successfully enhanced engine performance, but the resulting heat increased engine knock [fuel detonation] and structural wear. These effects could be offset with improved cooling, lubrication, and fuel mixtures. The NACA researchers in the Fuels and Lubrication Division concentrated on new synthetic fuels, higher octane fuels, and fuel-injection systems. The laboratory studied 16 different types of fuel blends during the war, including extensive investigations of triptane and xylidine.

2nd Annual Postdoc Research Day: US Army Research Laboratory PosterSymposia and Activities

DTIC Science & Technology

2018-04-12

ARL-SR-0394•APR 2018 US Army Research Laboratory 2nd Annual Postdoc Research Day: US Army Research Laboratory Poster Symposia and Activities by...Do not return it to the originator. ARL-SR-0394•APR 2018 US Army Research Laboratory 2nd Annual Postdoc Research Day: US Army Research Laboratory...Poster Symposia and Activities by Efraín Hernández–Rivera Weapons and Materials Research Directorate, ARL Julia Cline Oak Ridge Institute for Science and

Design and Calibration of the US Army Research Laboratory (ARL) Closed Loop Laboratory Radio Frequency (RF) Propagation Section

DTIC Science & Technology

2016-10-01

ARL-TR-7860 ● OCT 2016 US Army Research Laboratory Design and Calibration of the US Army Research Laboratory (ARL) Closed Loop ...ARL-TR-7860 ● OCT 2016 US Army Research Laboratory Design and Calibration of the US Army Research Laboratory (ARL) Closed Loop Laboratory...Design and Calibration of the US Army Research Laboratory (ARL) Closed Loop Laboratory Radio Frequency (RF) Propagation Section 5a. CONTRACT NUMBER

Stirling laboratory research engine survey report

NASA Technical Reports Server (NTRS)

Anderson, J. W.; Hoehn, F. W.

1979-01-01

As one step in expanding the knowledge relative to and accelerating the development of Stirling engines, NASA, through the Jet Propulsion Laboratory (JPL), is sponsoring a program which will lead to a versatile Stirling Laboratory Research Engine (SLRE). An objective of this program is to lay the groundwork for a commercial version of this engine. It is important to consider, at an early stage in the engine's development, the needs of the potential users so that the SLRE can support the requirements of educators and researchers in academic, industrial, and government laboratories. For this reason, a survey was performed, the results of which are described.

Research and the planned Space Experiment Research and Processing Laboratory

NASA Technical Reports Server (NTRS)

2000-01-01

Researchers perform tests at Kennedy Space Center. New facilities for such research will be provided at the Space Experiment Research Procession Laboratory (SERPL). The SERPL is a planned 100,000-square-foot laboratory that will provide expanded and upgraded facilities for hosting International Space Station experiment processing. In addition, it will provide better support for other biological and life sciences payload processing at KSC. It will serve as a magnet facility for a planned 400-acre Space Station Commerce Park.

A 13-Week Research-Based Biochemistry Laboratory Curriculum

ERIC Educational Resources Information Center

Lefurgy, Scott T.; Mundorff, Emily C.

2017-01-01

Here, we present a 13-week research-based biochemistry laboratory curriculum designed to provide the students with the experience of engaging in original research while introducing foundational biochemistry laboratory techniques. The laboratory experience has been developed around the directed evolution of an enzyme chosen by the instructor, with…

Research and the planned Space Experiment Research and Processing Laboratory

NASA Technical Reports Server (NTRS)

2000-01-01

Original photo and caption dated August 14, 1995: 'KSC plant physiologist Dr. Gary Stutte harvests a potato grown in the Biomass Production Chamber of the Controlled environment Life Support system (CELSS) in Hangar L at Cape Canaveral Air Station. During a 418-day 'human rated' experiment, potato crops grown in the chamber provided the equivalent of a continuous supply of the oxygen for one astronaut, along with 55 percent of that long-duration space flight crew member's caloric food requirements and enough purified water for four astronauts while absorbing their expelled carbon dioxide. The experiment provided data that will help demonstarte the feasibility of the CELSS operating as a bioregenerative life support system for lunar and deep-space missions that can operate independently without the need to carry consumables such as air, water and food, while not requiring the expendable air and water system filters necessary on today's human-piloted spacecraft.' His work is an example of the type of life sciences research that will be conducted at the Space Experiment Research Procession Laboratory (SERPL). The SERPL is a planned 100,000-square-foot laboratory that will provide expanded and upgraded facilities for hosting International Space Station experiment processing. In addition, it will provide better support for other biological and life sciences payload processing at KSC. It will serve as a magnet facility for a planned 400-acre Space Station Commerce Park.

Research and the planned Space Experiment Research and Processing Laboratory

NASA Technical Reports Server (NTRS)

2000-01-01

Original photo and caption dated August 14, 1995: 'KSC plant physiologist Dr. Gary Stutte (right) and Cheryl Mackowiak harvest potatoes grown in the Biomass Production Chamber of the Controlled Enviornment Life Support System (CELSS in Hangar L at Cape Canaveral Air Station. During a 418-day 'human rated' experiment, potato crops grown in the chamber provided the equivalent of a continuous supply of the oxygen for one astronaut, along with 55 percent of that long-duration space flight crew member's caloric food requirements and enough purified water for four astronauts while absorbing their expelled carbon dioxide. The experiment provided data that will help demonstarte the feasibility of the CELSS operating as a bioregenerative life support system for lunar and deep-space missions that can operate independently without the need to carry consumables such as air, water and food, while not requiring the expendable air and water system filters necessary on today's human-piloted spacecraft.' Their work is an example of the type of life sciences research that will be conducted at the Space Experiment Research Procession Laboratory (SERPL). The SERPL is a planned 100,000-square-foot laboratory that will provide expanded and upgraded facilities for hosting International Space Station experiment processing. In addition, it will provide better support for other biological and life sciences payload processing at KSC. It will serve as a magnet facility for a planned 400-acre Space Station Commerce Park.

Free-space optical communications research and demonstrations at the U.S. Naval Research Laboratory.

PubMed

Rabinovich, W S; Moore, C I; Mahon, R; Goetz, P G; Burris, H R; Ferraro, M S; Murphy, J L; Thomas, L M; Gilbreath, G C; Vilcheck, M; Suite, M R

2015-11-01

Free-space optical communication can allow high-bandwidth data links that are hard to detect, intercept, or jam. This makes them attractive for many applications. However, these links also require very accurate pointing, and their availability is affected by weather. These challenges have limited the deployment of free-space optical systems. The U.S. Naval Research Laboratory has, for the last 15 years, engaged in research into atmospheric propagation and photonic components with a goal of characterizing and overcoming these limitations. In addition several demonstrations of free-space optical links in real-world Navy applications have been conducted. This paper reviews this work and the principles guiding it.

Sandia National Laboratories: Research

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

Writing Material in Chemical Physics Research: The Laboratory Notebook as Locus of Technical and Textual Integration

ERIC Educational Resources Information Center

Wickman, Chad

2010-01-01

This article, drawing on ethnographic study in a chemical physics research facility, explores how notebooks are used and produced in the conduct of laboratory science. Data include written field notes of laboratory activity; visual documentation of "in situ" writing processes; analysis of inscriptions, texts, and material artifacts produced in the…

A research update for southeast poultry research laboratory

USDA-ARS?s Scientific Manuscript database

The Southeast Poultry Research Laboratory continues with their modernization plan. The 35% architectural drawings have been completed and the project is currently out for bid for the completion of the design and building of the new facility. Research activities in the Exotic and Emerging Avian Vir...

Discourse, Power, and Knowledge in the Management of "Big Science": The Production of Consensus in a Nuclear Fusion Research Laboratory.

ERIC Educational Resources Information Center

Kinsella, William J.

1999-01-01

Extends a Foucauldian view of power/knowledge to the archetypical knowledge-intensive organization, the scientific research laboratory. Describes the discursive production of power/knowledge at the "big science" laboratory conducting nuclear fusion research and illuminates a critical incident in which the fusion research…

Adaptive Training and Education Research at the US Army Research Laboratory: Bibliography (2016-2017)

DTIC Science & Technology

2018-03-05

Validation suite. Synthetic training environments. Service orientated architecture. Citation: Robson, E., Ray, F., Sinatra, A. M., & Sinatra, A. M. (2017...ARL-SR-0393 ● MAR 2018 US Army Research Laboratory Adaptive Training and Education Research at the US Army Research Laboratory... Training and Education Research at the US Army Research Laboratory: Bibliography (2016–2017) by Robert A Sottilare Human Research and

Research and Development. Laboratory Activities.

ERIC Educational Resources Information Center

Gallaway, Ann, Ed.

Research and Development is a laboratory-oriented course that includes the appropriate common essential elements for industrial technology education plus concepts and skills related to research and development. This guide provides teachers of the course with learning activities for secondary students. Introductory materials include an…

Supercharger Research at the Aircraft Engine Research Laboratory

NASA Image and Video Library

1944-01-21

A researcher in the Supercharger Research Division at the National Advisory Committee for Aeronautics (NACA) Aircraft Engine Research Laboratory measures the blade thickness on a supercharger. Superchargers were developed at General Electric used to supply additional air to reciprocating engines. The extra air resulted in increased the engine’s performance, particularly at higher altitudes. The Aircraft Engine Research Laboratory had an entire division dedicated to superchargers during World War II. General Electric developed the supercharger in response to a 1917 request from the NACA to develop a device to enhance high-altitude flying. The supercharger pushed larger volumes of air into the engine manifold. The extra oxygen allowed the engine to operate at its optimal sea-level rating even when at high altitudes. Thus, the aircraft could maintain its climb rate, maneuverability and speed as it rose higher into the sky. NACA work on the supercharger ceased after World War II due to the arrival of the turbojet engine. The Supercharger Research Division was disbanded in October 1945 and reconstituted as the Compressor and Turbine Division.

Laboratory directed research and development program, FY 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-02-01

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab) Laboratory Directed Research and Development Program FY 1996 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the projects supported and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The Berkeley Lab LDRD program is a critical tool for directing the Laboratory`s forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program provides themore » resources for Berkeley Lab scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also advances the Laboratory`s core competencies, foundations, and scientific capability, and permits exploration of exciting new opportunities. Areas eligible for support include: (1) Work in forefront areas of science and technology that enrich Laboratory research and development capability; (2) Advanced study of new hypotheses, new experiments, and innovative approaches to develop new concepts or knowledge; (3) Experiments directed toward proof of principle for initial hypothesis testing or verification; and (4) Conception and preliminary technical analysis to explore possible instrumentation, experimental facilities, or new devices.« less

A Research-Based Laboratory Course Designed to Strengthen the Research-Teaching Nexus

ERIC Educational Resources Information Center

Parra, Karlett J.; Osgood, Marcy P.; Pappas, Donald L., Jr.

2010-01-01

We describe a 10-week laboratory course of guided research experiments thematically linked by topic, which had an ultimate goal of strengthening the undergraduate research-teaching nexus. This undergraduate laboratory course is a direct extension of faculty research interests. From DNA isolation, characterization, and mutagenesis, to protein…

A Research Update for Southeast Poultry Research Laboratory

USDA-ARS?s Scientific Manuscript database

The Southeast Poultry Research Laboratory continues with their modernization plan. The 35% architectural drawings have been completed and the project is currently out for bid for the completion of the design and building of the new facility. Research activities include responding to the H7N9 highl...

41 CFR 101-25.109 - Laboratory and research equipment.

Code of Federal Regulations, 2011 CFR

2011-07-01

... equipped and/or used for scientific research, testing, or analysis, except clinical laboratories operating... 41 Public Contracts and Property Management 2 2011-07-01 2007-07-01 true Laboratory and research...-General Policies § 101-25.109 Laboratory and research equipment. (a) This section prescribes controls for...

Estimation on the self recovery behavior of low-conductivity layer in landfill final cover by laboratory conductivity tests.

PubMed

Kwon, O; Park, J

2006-11-01

This study examined the application of a Self Recovering Sustainable Layer (SRSL) as a landfill final cover. Low-conductivity layers in landfill covers are known to have problems associated with cracking as a result of the differential settlement or climatic changes. A SRSL is defined as a layer with chemical properties that reduces the increased hydraulic conductivity resulting from cracking by forming low-conductivity precipitates of chemicals contained in the layer. In this study, the formation of precipitates was confirmed using a batch test, spectroscopic analysis and mineralogical speciation tests. The possibility of secondary contamination due to the chemicals used for recovery was evaluated using a leaching test. A laboratory conductivity test was performed on a single layer composed of each chemical as well as on a 2-layer system. The recovery performance of the SRSL was estimated by developing artificial cracks in the specimens and observing the change in hydraulic conductivity as a function of time. In the laboratory conductivity test, the hydraulic conductivity of a 2-layer system as well as those of the individual layers that comprise the 2-layer system was estimated. In addition sodium ash was found to enhance the reduction in conductivity. A significant increase in conductivity was observed after the cracks developed but this was reduced with time, which indicated that the SRSL has a proper recovering performance. In conclusion, a SRSL can be used as a landfill final cover that could maintain low-conductivity even after the serious damages due to settlement.

Sandia National Laboratories: Research: Research Foundations: Nanodevices

Science.gov Websites

; Technology Defense Systems & Assessments About Defense Systems & Assessments Program Areas Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

Laboratory Animal Technician | Center for Cancer Research

Cancer.gov

PROGRAM DESCRIPTION The Laboratory Animal Sciences Program (LASP) provides exceptional quality animal care and technical support services for animal research performed at the National Cancer Institute at the Frederick National Laboratory for Cancer Research. LASP executes this mission by providing a broad spectrum of state-of-the-art technologies and services that are focused

21 CFR 58.130 - Conduct of a nonclinical laboratory study.

Code of Federal Regulations, 2010 CFR

2010-04-01

... specimen in a manner that precludes error in the recording and storage of data. (d) Records of gross... that specimen histopathologically. (e) All data generated during the conduct of a nonclinical laboratory study, except those that are generated by automated data collection systems, shall be recorded...

21 CFR 58.130 - Conduct of a nonclinical laboratory study.

Code of Federal Regulations, 2013 CFR

2013-04-01

... specimen in a manner that precludes error in the recording and storage of data. (d) Records of gross... that specimen histopathologically. (e) All data generated during the conduct of a nonclinical laboratory study, except those that are generated by automated data collection systems, shall be recorded...

21 CFR 58.130 - Conduct of a nonclinical laboratory study.

Code of Federal Regulations, 2011 CFR

2011-04-01

... specimen in a manner that precludes error in the recording and storage of data. (d) Records of gross... that specimen histopathologically. (e) All data generated during the conduct of a nonclinical laboratory study, except those that are generated by automated data collection systems, shall be recorded...

Earth Resources Laboratory research and technology

NASA Technical Reports Server (NTRS)

1983-01-01

The accomplishments of the Earth Resources Laboratory's research and technology program are reported. Sensors and data systems, the AGRISTARS project, applied research and data analysis, joint research projects, test and evaluation studies, and space station support activities are addressed.

Electric conductivity for laboratory and field monitoring of induced partial saturation (IPS) in sands

NASA Astrophysics Data System (ADS)

Kazemiroodsari, Hadi

Liquefaction is loss of shear strength in fully saturated loose sands caused by build-up of excess pore water pressure, during moderate to large earthquakes, leading to catastrophic failures of structures. Currently used liquefaction mitigation measures are often costly and cannot be applied at sites with existing structures. An innovative, practical, and cost effective liquefaction mitigation technique titled "Induced Partial Saturation" (IPS) was developed by researchers at Northeastern University. The IPS technique is based on injection of sodium percarbonate solution into fully saturated liquefaction susceptible sand. Sodium percarbonate dissolves in water and breaks down into sodium and carbonate ions and hydrogen peroxide which generates oxygen gas bubbles. Oxygen gas bubbles become trapped in sand pores and therefore decrease the degree of saturation of the sand, increase the compressibility of the soil, thus reduce its potential for liquefaction. The implementation of IPS required the development and validation of a monitoring and evaluation technique that would help ensure that the sands are indeed partially saturated. This dissertation focuses on this aspect of the IPS research. The monitoring system developed was based on using electric conductivity fundamentals and probes to detect the transport of chemical solution, calculate degree of saturation of sand, and determine the final zone of partial saturation created by IPS. To understand the fundamentals of electric conductivity, laboratory bench-top tests were conducted using electric conductivity probes and small specimens of Ottawa sand. Bench-top tests were used to study rate of generation of gas bubbles due to reaction of sodium percarbonate solution in sand, and to confirm a theory based on which degree of saturation were calculated. In addition to bench-top tests, electric conductivity probes were used in a relatively large sand specimen prepared in a specially manufactured glass tank. IPS was

Visitor's Guide | Frederick National Laboratory for Cancer Research

Cancer.gov

The Frederick National Laboratory for Cancer Research headquarters are located at the Advanced Technology and Research Facility (ATRF), located at 8560 Progress Drive, Frederick Maryland. Additional offices and laboratories are locatedon the NC

Reliability and validity of job content questionnaire for university research laboratory staff in Malaysia.

PubMed

Nehzat, F; Huda, B Z; Tajuddin, S H Syed

2014-03-01

Job Content Questionnaire (JCQ) has been proven a reliable and valid instrument to assess job stress in many countries and among various occupations. In Malaysia, both English and Malay versions of the JCQ have been administered to automotive workers, schoolteachers, and office workers. This study assessed the reliability and validity of the instrument with research laboratory staff in a university. A cross sectional study was conducted among 258 research laboratory staff in Universiti Putra Malaysia (UPM). Malaysian laboratory staff who have worked for at least one year were randomly selected from nine faculties and institutes in the university that have research laboratory. A self-administered English and Malay version of Job Content Questionnaire (JCQ) was used. Three major scales of JCQ: decision latitude, psychological job demands, and social support were assessed. Cronbach's alpha coefficients of two scales were acceptable, decision latitude and psychological job demands (0.70 and 0.72, respectively), while Cronbach's alpha coefficient for social support (0.86) was good. Exploratory factor analysis showed five factors that correspond closely to the theoretical construct of the questionnaire. The results of this research suggest that the JCQ is reliable and valid for examining psychosocial work situations and job strain among research laboratory staff. Further studies should be done for confirmative results, and further evaluation is needed on the decision authority subscale for this occupation.

41 CFR 109-25.109 - Laboratory and research equipment.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Laboratory and research... PROCUREMENT 25-GENERAL 25.1-General Policies § 109-25.109 Laboratory and research equipment. The provisions of 41 CFR 101-25.109 and this section apply to laboratory and research equipment in the possession of...

Definition of experiments and instruments for a communication/navigation research laboratory. Volume 4: Programmatics

NASA Technical Reports Server (NTRS)

1972-01-01

Details are provided for scheduling, cost estimates, and support research and technology requirements for a space shuttle supported manned research laboratory to conduct selected communication and navigation experiments. A summary of the candidate program and its time phasing is included, as well as photographs of the 1/20 scale model of the shuttle supported Early Comm/Nav Research Lab showing the baseline, in-bay arrangement and the out-of-bay configuration.

Laboratory Directed Research and Development FY2001 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Al-Ayat, R

2002-06-20

Established by Congress in 1991, the Laboratory Directed Research and Development (LDRD) Program provides the Department of Energy (DOE)/National Nuclear Security Administration (NNSA) laboratories, like Lawrence Livermore National Laboratory (LLNL or the Laboratory), with the flexibility to invest up to 6% of their budget in long-term, high-risk, and potentially high payoff research and development (R&D) activities to support the DOE/NNSA's national security missions. By funding innovative R&D, the LDRD Program at LLNL develops and extends the Laboratory's intellectual foundations and maintains its vitality as a premier research institution. As proof of the Program's success, many of the research thrusts thatmore » started many years ago under LDRD sponsorship are at the core of today's programs. The LDRD Program, which serves as a proving ground for innovative ideas, is the Laboratory's most important single resource for fostering excellent science and technology for today's needs and tomorrow's challenges. Basic and applied research activities funded by LDRD enhance the Laboratory's core strengths, driving its technical vitality to create new capabilities that enable LLNL to meet DOE/NNSA's national security missions. The Program also plays a key role in building a world-class multidisciplinary workforce by engaging the Laboratory's best researchers, recruiting its future scientists and engineers, and promoting collaborations with all sectors of the larger scientific community.« less

Summer Research Program (1992). Graduate Student Research Program (GSRP) Reports. Volume 8. Phillips Laboratory.

DTIC Science & Technology

1992-12-28

Research Program Starfire Optical Range, Phillips Laboratory /LITE Kirtland Air Force Base, Albuquerque, NM 87117 Sponsored by: Air ... Phillips Laboratory Sponsored by: Air Force Office of Scientific Research Kirtland Air Force Base, Albuquerque, New Mexico September, 1992 18-1 PROGRESS...Report for: Summer Research Program Phillips Laboratory Sponsored by: Air

Historical perspectives on thermostructural research at the NACA Langley Aeronautical Laboratory from 1948 to 1958

NASA Technical Reports Server (NTRS)

Heldenfels, R. R.

1982-01-01

Some of the early research on structural problems produced by aerodynamic heating, conducted at the Langley Aeronautical Laboratory of the National Advisory Committee for Aeronautics from 1948 to 1958 is described. That was the last decade of the NACA; in 1958 NACA became the nucleus of NASA. The NACA initially contracted for research but was aware that a well-equipped and suitably staffed laboratory was required to fulfill its obligations. Langley was established in 1920; the other listed were added during the NACA expansion in the World War II years. Some specific research activities are described, starting with calculation of the temperature of the structure.

Historical perspectives on thermostructural research at the NACA Langley Aeronautical Laboratory from 1948 to 1958

NASA Astrophysics Data System (ADS)

Heldenfels, R. R.

Some of the early research on structural problems produced by aerodynamic heating, conducted at the Langley Aeronautical Laboratory of the National Advisory Committee for Aeronautics from 1948 to 1958 is described. That was the last decade of the NACA; in 1958 NACA became the nucleus of NASA. The NACA initially contracted for research but was aware that a well-equipped and suitably staffed laboratory was required to fulfill its obligations. Langley was established in 1920; the other listed were added during the NACA expansion in the World War II years. Some specific research activities are described, starting with calculation of the temperature of the structure.

Research Laboratories and Centers Fact Sheet

EPA Pesticide Factsheets

The Office of Research and Development is the research arm of the U.S. Environmental Protection Agency. It has three national laboratories and four national centers located in 14 facilities across the country.

Transparent Conducting Oxides: Status and Opportunities in Basic Research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Coutts, T. J.; Perkins, J. D.; Ginley, D.S.

1999-08-01

In this paper, we begin by discussing the historical background of transparent conducting oxides and then make some general remarks about their typical properties. This is followed by a short discussion of the desired properties for future applications (particularly photovoltaic devices). These are ambitious objectives but they provide targets for future basic research and development. Although it may be possible to obtain these properties in the laboratory, it is vital to ensure that account is taken of industrial perceptions to the development of the next generation of materials. Hence, we spend some time discussing industrial criteria. Next, we discuss keymore » physical properties that determine the macroscopic physical properties that, in turn, affect the performance of devices. Finally, we select several key topics that ought to be included in future basic research programs.« less

IN-SERVICE HYDRAULIC CONDUCTIVITY OF GCLS IN LANDFILL COVERS - LABORATORY AND FIELD STUDIES

EPA Science Inventory

Laboratory experiments using multi-species inorganic solutions (containing calcium and sodium) were conducted on specimens of a new geosynthetic clay liner (GCL) containing sodium bentonite to determine how cation exchange and desiccation affected the hydraulic conductivity. Calc...

Frederick National Laboratory and Georgetown University Launch Research and Education Collaboration | Frederick National Laboratory for Cancer Research

Cancer.gov

FREDERICK, Md. -- A new collaboration established between Georgetown University and the Frederick National Laboratory for Cancer Research aims to expand both institutions’ research and training missions in the biomedical sciences. Representatives f

Tour of Research Laboratories at the Ford Company

NASA Astrophysics Data System (ADS)

Reitz, J. R.

1981-01-01

A brief description of the physics programs encountered on the tour of the Ford Motor Company Research Laboratories is provided. A visit to the Research Laboratories of the Ford Motor Company is part of the Conference on Physics in the Automotive Industry. The visit will show a cross-section of the programs in Research Staff which are clearly identified as physics research as well as other areas where physicists have established themselves as dominant or team members in what might traditionally be regarded as the province of engineering R&D. After a brief orientation, the Conference visitors will be divided into tour groups and will visit laboratories involved in combustion research, arc-discharge physics, various spectroscopic applications, metal gauging, energy management, optical display systems and solar energy research. Synopses of the specific tour visits follow.

Laboratory Directed Research and Development FY-15 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pillai, Rekha Sukamar

The Laboratory Directed Research and Development (LDRD) Program at Idaho National Laboratory (INL) reports its status to the U.S. Department of Energy (DOE) by March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the laboratory director broad flexibility for program implementation. LDRD funds are obtained through a charge to all INL programs. This report includes summaries of all INL LDRD research activities supported during Fiscal Year (FY) 2015.

Laboratory Directed Research and Development FY-10 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dena Tomchak

2011-03-01

The FY 2010 Laboratory Directed Research and Development (LDRD) Annual Report is a compendium of the diverse research performed to develop and ensure the INL's technical capabilities can support the future DOE missions and national research priorities. LDRD is essential to the INL -- it provides a means for the laboratory to pursue novel scientific and engineering research in areas that are deemed too basic or risky for programmatic investments. This research enhances technical capabilities at the laboratory, providing scientific and engineering staff with opportunities for skill building and partnership development.

Conducting international nursing research: challenges and opportunities.

PubMed

Opollo, Jackline Gloria; Opollo, Diana Alaka; Gray, Jennifer; Spies, Lori

2014-11-01

To describe practical experiences before, during and after gaining entry into research fields in Kenya and Uganda. Planning, conducting and implementing international research can be an arduous task. Novice researchers need practical guides to accessing international fields and mitigating challenges met in the field. The researchers conducted three different studies in two developing nations. This paper reviews challenges encountered when conducting international research. Solutions used to overcome these challenges are discussed. Establishing and maintaining effective partnerships is critical to the success of international research efforts. Researchers must be tactful, flexible and creative when handling methodological, ethical and logistical challenges encountered in settings poor in resources. International research provides opportunities for increasing dedication, building cross-cultural competence and advancing health professional practice globally. This paper contributes to nursing scholarship by highlighting the practical challenges of conducting international research. Illustrations aimed at lending insight and encouraging others to expand their dedication to conducting international research are offered.

Benefits of Conducting Research.

ERIC Educational Resources Information Center

Anderson, Frances E.

2001-01-01

Metaphors for researchers, such as a crusader; a traveler; an explorer; a miner; an astronaut; a biblical Daniel; a Samurai; and an archaeologist are discussed. Benefits of conducting research are enumerated, including building the knowledge base for art therapy; increasing professional opportunities; improving client care; and advancing the…

USAF Summer Research Program - 1994 Graduate Student Research Program Final Reports, Volume 8, Phillips Laboratory

DTIC Science & Technology

1994-12-01

Research Group at the Phillips Laboratory at Kirtland Air Force Base...for Summer Graduate Student Research Program Phillips Laboratory Sponsored by: Air Force Office of Scientific Research Boiling Air Force Base, DC...2390 S. York Street Denver, CO 80208-0177 Final Report for: Summer Faculty Research Program Phillips Laboratory Sponsored by: Air Force

MIT Lincoln Laboratory Annual Report 2010

DTIC Science & Technology

2010-01-01

Research and Development Center (FFRDC) and a DoD Research and Development Laboratory. The Laboratory conducts research and development pertinent to...year, the Laboratory restruc- tured three divisions to focus research and development in areas that are increasingly important to the nation...the Director 3 Collaborations with MIT campus continue to grow, leveraging the strengths of researchers at both the Laboratory and campus. The

Fiberboard and hardboard research at the Forest Products Laboratory : a 50-year summary

Treesearch

Gary C. Myers; J. Dobbin McNatt

1985-01-01

Many changes have occurred in the fiber-based panel products industries during the past 50 years. During this timespan the Forest Products Laboratory has conducted a considerable amount of research on processing and product evaluation of fiber-based panel product materials. Unfortunately about 26 percent of this information was never published. completed during this...

Air Force Research Laboratory Sensors Directorate Leadership Legacy, 1960-2011

DTIC Science & Technology

2011-03-01

AFRL -RY-WP-TM-2011-1017 AIR FORCE RESEARCH LABORATORY SENSORS DIRECTORATE LEADERSHIP LEGACY, 1960-2011 Compiled by Raymond C. Rang...Structures Divi- sion, Space Vehicles Directorate, Air Force Research Laboratory , Kirtland AFB, N.M. 7. March 1998 - July 1999, Chief, Integration and... Research Laboratory ( AFRL ), and Deputy Director of the Sensors Direc- torate, Air Force Research

Commissioning a materials research laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

SAVAGE,GERALD A.

2000-03-28

This presentation covers the process of commissioning a new 150,000 sq. ft. research facility at Sandia National Laboratories. The laboratory being constructed is a showcase of modern design methods being built at a construction cost of less than $180 per sq. ft. This is possible in part because of the total commissioning activities that are being utilized for this project. The laboratory's unique approach to commissioning will be presented in this paper. The process will be followed through from the conceptual stage on into the actual construction portion of the laboratory. Lessons learned and cost effectiveness will be presented inmore » a manner that will be usable for others making commissioning related decisions. Commissioning activities at every stage of the design will be presented along with the attributed benefits. Attendees will hear answers to the what, when, who, and why questions associated with commissioning of this exciting project.« less

Air Force Research Laboratory, Edwards Air Force Base, CA

DTIC Science & Technology

2011-06-27

Air Force Research Laboratory (AFMC) AFRL /RZS 1 Ara Road Edwards AFB CA 93524-7013 AFRL -RZ-ED-VG-2011-269 9...SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) Air Force Research Laboratory (AFMC) AFRL /RZS 11. SPONSOR...Form 298 (Rev. 8-98) Prescribed by ANSI Std. 239.18 Air Force Research Laboratory Ed d Ai F B CA Col Mike Platt war s r orce

Pacific Northwest Laboratory annual report for 1990 to the DOE Office of Energy Research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Park, J.F.

This report summarizes progress on OHER human health, biological, and general life sciences research programs conducted at PNL in FY 1990. The research develops the knowledge and scientific principles necessary to identify understand, and anticipate the long-term health consequences of energy-related radiation and chemicals. Our continuing emphasis is to decrease the uncertainty of health risk estimates from existing and developing energy-related technologies through an increased of understanding of how radiation and chemicals cause biological damage. The sequence of this report of PNL research reflects the OHER programmatic structure. The first section, on human health research, concerns epidemiological and statistical studiesmore » for assessing health risks. The next section contains reports of biological research in laboratory animals and in vitro cell systems, including research with radionuclides and chemicals. The general life sciences research section reports research conducted for the OHER human genome research program.« less

Four Decades of Ground-Breaking Research in the Reproductive and Developmental Sciences: The Infant Primate Research Laboratory at the University of Washington National Primate Research Center

PubMed Central

Burbacher, Thomas M.; Grant, Kimberly S.; Worlein, Julie; Ha, James; Curnow, Eliza; Juul, Sandra; Sackett, Gene P.

2017-01-01

The Infant Primate Research Laboratory (IPRL) was established in the 1970s at the University of Washington as a visionary project of Dr. Gene (Jim) P. Sackett. Supported by a collaboration between the Washington National Primate Research Center and the Center on Human Health and Disability, the IPRL operates under the principle that learning more about the causes of abnormal development in macaque monkeys will provide important insights into mechanisms underlying childhood neurodevelopmental disorders. Over the past forty years, a broad range of research projects have been conducted at the IPRL. Some have described the normal expression of species-typical behaviors in nursery-reared macaques while others have focused on specific issues in perinatal medicine and research. This article will review the unique history of the IPRL and the scientific contributions produced by research conducted in the laboratory. Past and present investigations at the IPRL have explored the consequences of adverse early rearing, low-birth-weight, prematurity, epilepsy, chemical/drug exposure, viral infection, diarrheal disease, vaccine safety, assisted reproductive technologies and perinatal hypoxia on growth and development. New directions of investigation include the production of a transgenic primate model using our embryonic stem cell-based technology to better understand and treat heritable forms of human mental retardation such as fragile X. PMID:23873400

Air Force Research Laboratory’s Focused Long Term Challenges

DTIC Science & Technology

2008-04-01

Air Force Research Laboratory ( AFRL ) mission is to provide support to the Air Force (AF) and the warfighters with... Air Force Research Laboratory’s Focused Long Term Challenges Leo J Rose Munitions Directorate, Air Force Research Laboratory , 101 W Eglin Blvd...This technology vision, which was born in our Air Force Research Laboratory , builds on the Air Force’s traditional kill

49 CFR 40.89 - What is validity testing, and are laboratories required to conduct it?

Code of Federal Regulations, 2013 CFR

2013-10-01

... PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.89 What is validity testing, and are laboratories required to conduct it? (a) Specimen validity testing is... 49 Transportation 1 2013-10-01 2013-10-01 false What is validity testing, and are laboratories...

49 CFR 40.89 - What is validity testing, and are laboratories required to conduct it?

Code of Federal Regulations, 2011 CFR

2011-10-01

... PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.89 What is validity testing, and are laboratories required to conduct it? (a) Specimen validity testing is... 49 Transportation 1 2011-10-01 2011-10-01 false What is validity testing, and are laboratories...

49 CFR 40.89 - What is validity testing, and are laboratories required to conduct it?

Code of Federal Regulations, 2010 CFR

2010-10-01

... PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.89 What is validity testing, and are laboratories required to conduct it? (a) Specimen validity testing is... 49 Transportation 1 2010-10-01 2010-10-01 false What is validity testing, and are laboratories...

49 CFR 40.89 - What is validity testing, and are laboratories required to conduct it?

Code of Federal Regulations, 2012 CFR

2012-10-01

... PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.89 What is validity testing, and are laboratories required to conduct it? (a) Specimen validity testing is... 49 Transportation 1 2012-10-01 2012-10-01 false What is validity testing, and are laboratories...

49 CFR 40.89 - What is validity testing, and are laboratories required to conduct it?

Code of Federal Regulations, 2014 CFR

2014-10-01

... PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.89 What is validity testing, and are laboratories required to conduct it? (a) Specimen validity testing is... 49 Transportation 1 2014-10-01 2014-10-01 false What is validity testing, and are laboratories...

Nanoscience and Technology at the Air Force Research Laboratory (AFRL)

DTIC Science & Technology

2005-05-01

AIR FORCE RESEARCH LABORATORY ( AFRL ) Dr. Richard A. Vaia Dr. Daniel Miracle Dr. Thomas Cruse Air Force Research ...Technology At The Air Force Research Laboratory ( AFRL ) 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT...98) Prescribed by ANSI Std Z39-18 AFRL NST Overview 2 AIR FORCE RESEARCH LABORATORY VISION We defend

Nanoscience and Technology at the Air Force Research Laboratory (AFRL)

DTIC Science & Technology

2005-02-01

AIR FORCE RESEARCH LABORATORY ( AFRL ) Dr. Richard A. Vaia Dr. Daniel Miracle Dr. Thomas Cruse Air Force Research ...Technology At The Air Force Research Laboratory ( AFRL ) 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT...98) Prescribed by ANSI Std Z39-18 AFRL NST Overview 2 AIR FORCE RESEARCH LABORATORY VISION We defend

Laboratory Directed Research and Development Annual Report FY 2017

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sullivan, Kelly O.

A national laboratory must establish and maintain an environment in which creativity and innovation are encouraged and supported in order to fulfill its missions and remain viable in the long term. As such, multiprogram laboratories are given discretion to allocate a percentage of their operating budgets to support research and development projects that align to PNNL’s and DOE’s missions and support the missions of other federal agencies, including DHS, DOD, and others. DOE Order 413.2C sets forth DOE’s Laboratory Directed Research and Development (LDRD) policy and guidelines for DOE multiprogram laboratories, and it authorizes the national laboratories to allocate upmore » to 6 percent of their operating budgets to fund the program. LDRD is innovative research and development, selected by the Laboratory Director or his/her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory. The projects supported by LDRD funding all have demonstrable ties to DOE/DHS missions and may also be relevant to the missions of other federal agencies that sponsor work at the Laboratory. The program plays a key role in attracting the best and brightest scientific staff, which is needed to serve the highest priority DOE mission objectives. Individual project reports comprise the bulk of this LDRD report. The Laboratory focuses its LDRD research on scientific assets that often address more than one scientific discipline.« less

Laboratory Directed Research and Development Annual Report FY 2016

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sullivan, Kelly O.

A national laboratory must establish and maintain an environment in which creativity and innovation are encouraged and supported in order to fulfill its missions and remain viable in the long term. As such, multiprogram laboratories are given discretion to allocate a percentage of their operating budgets to support research and development projects that align to PNNL’s and DOE’s missions and support the missions of other federal agencies, including DHS, DOD, and others. DOE Order 413.2C sets forth DOE’s Laboratory Directed Research and Development (LDRD) policy and guidelines for DOE multiprogram laboratories, and it authorizes the national laboratories to allocate upmore » to 6 percent of their operating budgets to fund the program. LDRD is innovative research and development, selected by the Laboratory Director or his/her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory. The projects supported by LDRD funding all have demonstrable ties to DOE/DHS missions and may also be relevant to the missions of other federal agencies that sponsor work at the Laboratory. The program plays a key role in attracting the best and brightest scientific staff, which is needed to serve the highest priority DOE mission objectives. Individual project reports comprise the bulk of this LDRD report. The Laboratory focuses its LDRD research on scientific assets that often address more than one scientific discipline.« less

Summer Research Program (1992). Summer Faculty Research Program (SFRP) Reports. Volume 3. Phillips Laboratory.

DTIC Science & Technology

1992-12-28

Phillips Laboratory Kirtland Air Force Base NM 87117-6008 Sponsored by: Air Force Office of Scientific Research Bolling Air Force Base...Zindel, D.: 1963, Z. Astrophys. 57, 82. 29-13 FINAL REPORT SUMMER FACULTY RESEARCH PROGRAM AT PHILLIPS LABORATORY KIRTLAND AIR FORCE BASE...Program Phillips Laboratory Sponsored by: Air Force Office of Scientific

Sandia National Laboratories: Research: Biodefense

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

Sandia National Laboratories: Research: Bioscience

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

Senior Laboratory Animal Technician | Center for Cancer Research

Cancer.gov

PROGRAM DESCRIPTION The Laboratory Animal Sciences Program (LASP) provides exceptional quality animal care and technical support services for animal research performed at the National Cancer Institute at the Frederick National Laboratory for Cancer Research. LASP executes this mission by providing a broad spectrum of state-of-the-art technologies and services that are focused

Definition of experiments and instruments for a communication/navigation research laboratory. Volume 3: Laboratory descriptions

NASA Technical Reports Server (NTRS)

1972-01-01

The following study objectives are covered: (1) identification of major laboratory equipment; (2) systems and operations analysis in support of the laboratory design; and (3) conceptual design of the comm/nav research laboratory.

Opportunities for Multidisciplinary Research in Partnership with Rock Engineers at the Deep Underground Science and Engineering Laboratory

NASA Astrophysics Data System (ADS)

Laughton, C.

2008-12-01

For the last half century the physics community has increasingly turned to the use of underground space to conduct basic research. The community is currently planning to conduct a new generation of underground experiments at the Deep Underground Science and Engineering Laboratory (DUSEL). DUSEL will be constructed within the footprint of the defunct Homestake Gold Mine, located in Lead, South Dakota. Physics proposals call for the construction of new caverns in which to conduct major new experiments. Some of the proposed laboratory facilities will be significantly larger and deeper than any previously constructed. The talk will highlight possible opportunities for integrating multi-disciplinary research in to the cavern construction program, and will stress the need to work closely with design and construction contractors to ensure that research goals can be achieve with minimal impact on project work. The constructors of large caverns should be particularly receptive to, and encouraging of geoscience research that could improve the engineering characterization of the rock mass. An improved understanding of the rock mass, as the host construction material, would result in a more reliable cavern design and construction process, and a reduced construction risk to the Project.

Conducting Research With Community Groups.

PubMed

Doornbos, Mary Molewyk; Ayoola, Adejoke; Topp, Robert; Zandee, Gail Landheer

2015-10-01

Nurse scientists are increasingly recognizing the necessity of conducting research with community groups to effectively address complex health problems and successfully translate scientific advancements into the community. Although several barriers to conducting research with community groups exist, community-based participatory research (CBPR) has the potential to mitigate these barriers. CBPR has been employed in programs of research that respond in culturally sensitive ways to identify community needs and thereby address current health disparities. This article presents case studies that demonstrate how CBPR principles guided the development of (a) a healthy body weight program for urban, underserved African American women; (b) a reproductive health educational intervention for urban, low-income, underserved, ethnically diverse women; and (c) a pilot anxiety/depression intervention for urban, low-income, underserved, ethnically diverse women. These case studies illustrate the potential of CBPR as an orientation to research that can be employed effectively in non-research-intensive academic environments. © The Author(s) 2015.

Conducting Research with Community Groups

PubMed Central

Doornbos, Mary Molewyk; Ayoola, Adejoke; Topp, Robert; Zandee, Gail Landheer

2016-01-01

Nurse scientists are increasingly recognizing the necessity of conducting research with community groups to effectively address complex health problems and successfully translate scientific advancements into the community. While several barriers to conducting research with community groups exist, community based participatory research (CBPR) has the potential to mitigate these barriers. CBPR has been employed in programs of research that respond in culturally sensitive ways to identify community needs and thereby address current health disparities. This manuscript presents case studies that demonstrate how CBPR principles guided the development of: (a) a healthy body weight program for urban, underserved African-American women, (b) a reproductive health educational intervention for urban, low-income, underserved, ethnically diverse women, and (c) a pilot anxiety/depression intervention for urban, low-income, underserved, ethnically diverse women. These case studies illustrate the potential of CBPR as an orientation to research that can be employed effectively in non-research intensive academic environments. PMID:25724557

1999 LDRD Laboratory Directed Research and Development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rita Spencer; Kyle Wheeler

This is the FY 1999 Progress Report for the Laboratory Directed Research and Development (LDRD) Program at Los Alamos National Laboratory. It gives an overview of the LDRD Program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principal investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic, molecular, optical, and plasma physics, fluids, and particle beams, (5)more » engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.« less

Virtual Instruction: A Qualitative Research Laboratory Course

ERIC Educational Resources Information Center

Stadtlander, Lee M.; Giles, Martha J.

2010-01-01

Online graduate programs in psychology are becoming common; however, a concern has been whether instructors in the programs provide adequate research mentoring. One issue surrounding research mentoring is the absence of research laboratories in the virtual university. Students attending online universities often do research without peer or lab…

Current safety practices in nano-research laboratories in China.

PubMed

Zhang, Can; Zhang, Jing; Wang, Guoyu

2014-06-01

China has become a key player in the global nanotechnology field, however, no surveys have specifically examined safety practices in the Chinese nano-laboratories in depth. This study reports results of a survey of 300 professionals who work in research laboratories that handle nanomaterials in China. We recruited participants at three major nano-research laboratories (which carry out research in diverse fields such as chemistry, material science, and biology) and the nano-chemistry session of the national meeting of the Chinese Chemical Society. Results show that almost all nano-research laboratories surveyed had general safety regulations, whereas less than one third of respondents reported having nanospecific safety rules. General safety measures were in place in most surveyed nano-research laboratories, while nanospecific protective measures existed or were implemented less frequently. Several factors reported from the scientific literature including nanotoxicology knowledge gaps, technical limitations on estimating nano-exposure, and the lack of nano-occupational safety legislation may contribute to the current state of affairs. With these factors in mind and embracing the precautionary principle, we suggest strengthening or providing nanosafety training (including raising risk awareness) and establishing nanosafety guidelines in China, to better protect personnel in the nano-workplace.

Guard House at the Aircraft Engine Research Laboratory

NASA Image and Video Library

1945-08-21

A vehicle leaves the National Advisory Committee for Aeronautics (NACA) Aircraft Engine Research Laboratory on August 14, 1945. At 7 p.m. that evening President Truman announced that Japan had accepted terms for surrender and World War II was over. The end of the war brought significant changes for the laboratory. The NACA would cease its troubleshooting of military aircraft and return to research. Researchers would increase their efforts to address the new technologies that emerged during the war. The entire laboratory was reorganized in October to better investigate turbojets, ramjets, and rockets. The guard house sat on the main entrance to the laboratory off of Brookpark Road. The building was fairly small and easily crowded. In the early 1960s a new security facility was built several hundred feet beyond the original guard house. The original structure remained in place for several years but was not utilized. The subsequent structure was replaced in 2011 by a new building and entrance configuration.

Science and Technology: The Making of the Air Force Research Laboratory

DTIC Science & Technology

2000-01-01

AFRL . . . . . . . . . . . 187 11 Air Force Research Laboratory : Before and After...United States Air Force during my tenure as chief of staff—the crea - tion of the Air Force Research Laboratory ( AFRL ). As the “high technology” service...consolidate four existing laboratories into one Air Force Research Laboratory ( AFRL ) designed to lead to a more efficient and streamlined

Conducting Research in School Systems.

ERIC Educational Resources Information Center

Schutz, Richard E.

The problems of conducting research in schools are discussed. Solutions to social psychological problems are suggested, and an improved design for research is recommended. Clearer definition of terminology is recommended to avoid the confusion that can result from ambiguous terms. A research design should be adaptable to the administrative and…

USAF Summer Research Program - 1993 Graduate Student Research Program Final Reports, Volume 8, Phillips Laboratory

DTIC Science & Technology

1994-12-01

Research Program Phillips Laboratory Kirtland Air Force Base Albuquerque, New Mexico Sponsored by: Air ...Summer Research Program Phillips Laboratory Sponsored by. Air Force Office of Scientific Research Kirtland Air Force Base, Albuquerque, New Mexico...UNITED STATES AIR FORCE SUMMER RESEARCH PROGRAM -- 1993 SUMMER RESEARCH PROGRAM FINAL REPORTS VOLUME 8

Biological and Physical Space Research Laboratory 2002 Science Review

NASA Technical Reports Server (NTRS)

Curreri, P. A. (Editor); Robinson, M. B. (Editor); Murphy, K. L. (Editor)

2003-01-01

With the International Space Station Program approaching core complete, our NASA Headquarters sponsor, the new Code U Enterprise, Biological and Physical Research, is shifting its research emphasis from purely fundamental microgravity and biological sciences to strategic research aimed at enabling human missions beyond Earth orbit. Although we anticipate supporting microgravity research on the ISS for some time to come, our laboratory has been vigorously engaged in developing these new strategic research areas.This Technical Memorandum documents the internal science research at our laboratory as presented in a review to Dr. Ann Whitaker, MSFC Science Director, in July 2002. These presentations have been revised and updated as appropriate for this report. It provides a snapshot of the internal science capability of our laboratory as an aid to other NASA organizations and the external scientific community.

Manual wheeled mobility--current and future developments from the human engineering research laboratories.

PubMed

Cooper, Rory A; Koontz, Alicia M; Ding, Dan; Kelleher, Annmarie; Rice, Ian; Cooper, Rosemarie

2010-01-01

Medical rehabilitation and assistive technology are immersed in a world transitioning to a basis in evidence-based practice. Fortunately, there is a growing body of knowledge related to manual wheelchair mobility to form a basis for clinical decision making. The results from research studies are useful for designing better wheelchairs, fitting and training people appropriately, contributing to evidence-based-medicine and guiding future research. This review describes some of the work related to manual wheelchairs that has and is being conducted within the University of Pittsburgh and the Human Engineering Research Laboratories of the United States Department of Veterans Affairs, and its application.

Laboratory Directed Research and Development 1998 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pam Hughes; Sheila Bennett eds.

1999-07-14

The Laboratory's Directed Research and Development (LDRD) program encourages the advancement of science and the development of major new technical capabilities from which future research and development will grow. Through LDRD funding, Pacific Northwest continually replenishes its inventory of ideas that have the potential to address major national needs. The LDRD program has enabled the Laboratory to bring to bear its scientific and technical capabilities on all of DOE's missions, particularly in the arena of environmental problems. Many of the concepts related to environmental cleanup originally developed with LDRD funds are now receiving programmatic support from DOE, LDRD-funded work inmore » atmospheric sciences is now being applied to DOE's Atmospheric Radiation Measurement Program. We also have used concepts initially explored through LDRD to develop several winning proposals in the Environmental Management Science Program. The success of our LDRD program is founded on good management practices that ensure funding is allocated and projects are conducted in compliance with DOE requirements. We thoroughly evaluate the LDRD proposals based on their scientific and technical merit, as well as their relevance to DOE's programmatic needs. After a proposal is funded, we assess progress annually using external peer reviews. This year, as in years past, the LDRD program has once again proven to be the major enabling vehicle for our staff to formulate new ideas, advance scientific capability, and develop potential applications for DOE's most significant challenges.« less

Our Story | Materials Research Laboratory at UCSB: an NSF MRSEC

Science.gov Websites

this site Materials Research Laboratory at UCSB: an NSF MRSEC logo Materials Research Laboratory at & Workshops Visitor Info Research IRG-1: Magnetic Intermetallic Mesostructures IRG 2: Polymeric Seminars Publications MRL Calendar Facilities Computing Energy Research Facility Microscopy &

The Johns Hopkins Hunterian Laboratory Philosophy: Mentoring Students in a Scientific Neurosurgical Research Laboratory.

PubMed

Tyler, Betty M; Liu, Ann; Sankey, Eric W; Mangraviti, Antonella; Barone, Michael A; Brem, Henry

2016-06-01

After over 50 years of scientific contribution under the leadership of Harvey Cushing and later Walter Dandy, the Johns Hopkins Hunterian Laboratory entered a period of dormancy between the 1960s and early 1980s. In 1984, Henry Brem reinstituted the Hunterian Neurosurgical Laboratory, with a new focus on localized delivery of therapies for brain tumors, leading to several discoveries such as new antiangiogenic agents and Gliadel chemotherapy wafers for the treatment of malignant gliomas. Since that time, it has been the training ground for 310 trainees who have dedicated their time to scientific exploration in the lab, resulting in numerous discoveries in the area of neurosurgical research. The Hunterian Neurosurgical Laboratory has been a unique example of successful mentoring in a translational research environment. The laboratory's philosophy emphasizes mentorship, independence, self-directed learning, creativity, and people-centered collaboration, while maintaining productivity with a focus on improving clinical outcomes. This focus has been served by the diverse backgrounds of its trainees, both in regard to educational status as well as culturally. Through this philosophy and strong legacy of scientific contribution, the Hunterian Laboratory has maintained a positive and productive research environment that supports highly motivated students and trainees. In this article, the authors discuss the laboratory's training philosophy, linked to the principles of adult learning (andragogy), as well as the successes and the limitations of including a wide educational range of students in a neurosurgical translational laboratory and the phenomenon of combining clinical expertise with rigorous scientific training.

USAF Summer Research Program - 1993 Summer Research Extension Program Final Reports, Volume 2, Phillips Laboratory

DTIC Science & Technology

1994-11-01

Research Extension Program Phillips Laboratory Kirtland Air Force Base Sponsored by: Air Force Office of Scientific Research Boiling Air Force Base...Program Phillips Laboratory Sponsored by: Air Force Office of Scientific Research Bolling Air Force Base, Washington, D.C. and Arkansas Tech University...Summer Research Extension Program (SREP) Phillips

Pacific Northwest Laboratory annual report for 1993 to the DOE Office of Energy Research. Part 2: Environmental sciences

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-04-01

This 1993 Annual Report from Pacific Northwest Laboratory (PNL) to the US DOE describes research in environment and health conducted during fiscal year (FY) 1993. The report is divided into four parts, each in a separate volume. This part, Volume 2, covers Environmental Sciences. The research is directed toward developing a fundamental understanding of subsurface and terrestrial systems as a basis for both managing these critical resources and addressing environmental problems such as environmental restoration and global change. There are sections on Subsurface Science, Terrestrial Science, Technology Transfer, Interactions with Educational Institutions, and Laboratory Directed Research and Development.

Flight Research Building at the Aircraft Engine Research Laboratory

NASA Image and Video Library

1942-09-21

The Flight Research Building at the National Advisory Committee for Aeronautics (NACA) Aircraft Engine Research Laboratory is a 272- by 150-foot hangar with an internal height up to 90 feet. The hangar’s massive 37.5-foot-tall and 250-foot-long doors can be opened in sections to suit different size aircraft. The hangar has sheltered a diverse fleet of aircraft over the decades. These have ranged from World War II bombers to Cessna trainers and from supersonic fighter jets to a DC–9 airliner. At the time of this September 1942 photograph, however, the hangar was being used as an office building during the construction of the laboratory. In December of 1941, the Flight Research Building became the lab’s first functional building. Temporary offices were built inside the structure to house the staff while the other buildings were completed. The hangar offices were used for an entire year before being removed in early 1943. It was only then that the laboratory acquired its first aircraft, pilots and flight mechanics. The temporary one-story offices can be seen in this photograph inside the large sliding doors. Also note the vertical lift gate below the NACA logo. The gate was installed so that the tails of larger aircraft could pass into the hangar. The white Farm House that served as the Administration Building during construction can be seen in the distance to the left of the hangar.

CONDUCTIVITY PROFILE RATE OF CHANGE FROM FIELD AND LABORATORY DATA WITHIN BIODEGRADING PETROLEUM HYDROCARBON

EPA Science Inventory

We present the results of long term (500 days) measurements of the bulk conductivity in a field and laboratory experiment. Our objective was to determine the rate of change in bulk conductivity and whether this rate of change correlated with the petroleum hydrocarbon degradation...

Laboratory Directed Research and Development Program FY 2008 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

editor, Todd C Hansen

2009-02-23

review by the Office of Science Program Offices, such as LDRD projects germane to new research facility concepts and new fundamental science directions. Berkeley Lab LDRD program also play an important role in leveraging DOE capabilities for national needs. The fundamental scientific research and development conducted in the program advances the skills and technologies of importance to our Work For Others (WFO) sponsors. Among many directions, these include a broad range of health-related science and technology of interest to the National Institutes of Health, breast cancer and accelerator research supported by the Department of Defense, detector technologies that should be useful to the Department of Homeland Security, and particle detection that will be valuable to the Environmental Protection Agency. The Berkeley Lab Laboratory Directed Research and Development Program FY2008 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the supported projects and summarizes their accomplishments. It constitutes a part of the LDRD program planning and documentation process that includes an annual planning cycle, project selection, implementation, and review.« less

US Army Research Laboratory (ARL) Robotics Collaborative Technology Alliance 2014 Capstone Experiment

DTIC Science & Technology

2016-07-01

ARL-TR-7729 ● JULY 2016 US Army Research Laboratory US Army Research Laboratory (ARL) Robotics Collaborative Technology Alliance...TR-7729 ● JULY 2016 US Army Research Laboratory US Army Research Laboratory (ARL) Robotics Collaborative Technology Alliance 2014 Capstone...National Robotics Engineering Center, Pittsburgh, PA Robert Dean, Terence Keegan, and Chip Diberardino General Dynamics Land Systems, Westminster

Laboratory Activities in Israel

ERIC Educational Resources Information Center

Mamlok-Naaman, Rachel; Barnea, Nitza

2012-01-01

Laboratory activities have long had a distinctive and central role in the science curriculum, and science educators have suggested that many benefits accrue from engaging students in science laboratory activities. Many research studies have been conducted to investigate the educational effectiveness of laboratory work in science education in…

Laboratory Directed Research and Development Program FY 2006 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sjoreen, Terrence P

2007-04-01

The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the US Departmental of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, 'Laboratory Directed Research and Development' (April 19, 2006), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2006. The associated FY 2006 ORNL LDRD Self-Assessment (ORNL/PPA-2007/2) provides financial data about themore » FY 2006 projects and an internal evaluation of the program's management process.« less

Nespoli conducts a test run with the French/CNES Neuroscientific Research Experiment

NASA Image and Video Library

2011-02-12

ISS026-E-027000 (12 Feb. 2011) --- European Space Agency (ESA) astronaut Paolo Nespoli, Expedition 26 flight engineer, conducts a test run with the French/CNES neuroscientific research experiment ?3D-Space? (SAP) in the Columbus laboratory of the International Space Station. While floating freely, Nespoli used the ESA multipurpose laptop with a prepared hard disk drive, data storage on a memory card, and an electronic pen table connected to it. 3D-Space, which involves distance, writing and illusion exercises, is designed to test the hypothesis that altered visual perception affects motor control.

How to Conduct Ethnographic Research

ERIC Educational Resources Information Center

Sangasubana, Nisaratana

2011-01-01

The purpose of this paper is to describe the process of conducting ethnographic research. Methodology definition and key characteristics are given. The stages of the research process are described including preparation, data gathering and recording, and analysis. Important issues such as reliability and validity are also discussed.

Laboratory Directed Research and Development Program Assessment for FY 2008

DOE Office of Scientific and Technical Information (OSTI.GOV)

Looney, J P; Fox, K J

2008-03-31

Brookhaven National Laboratory (BNL) is a multidisciplinary Laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal Year 2008 spending was $531.6 million. There are approximately 2,800 employees, and another 4,300 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annuallymore » in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development,' April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new 'fundable' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research 'which could lead to new programs, projects, and directions' for the Laboratory. To be a premier scientific Laboratory, BNL must continuously foster groundbreaking scientific research and renew its research agenda. The competition for LDRD funds stimulates Laboratory scientists to think in new and creative ways, which becomes a major factor in achieving and maintaining research excellence and a means to address National needs within the overall mission of the DOE and BNL. By fostering high-risk, exploratory research, the LDRD program helps BNL to respond new scientific opportunities

Operational readiness for conducting global health research abroad.

PubMed

McDonald, Judy M; Gyorkos, Theresa W

2016-12-27

Research excellence is the goal of all researchers. Conducting quality research with the ultimate aim of improving health is a shared goal among researchers in the global health domain. The competencies required for conducting and producing quality research in global health go far beyond the academic or scientific spheres. They incorporate aspects of research partnership, which places humility, empathy, and mutual respect at its core. Conducting quality respectful global health research requires an appropriate balance of operational readiness (i.e., technical, physical, and mental readiness). This paper reports on the pertinence and potential shaping of conceptual work and exploratory research focusing on aspects of mental readiness. These aspects may be perceived to be significant enough to influence success and warrant further investigation in the context of conducting global health research abroad.

ECOSYSTEM RESTORATION RESEARCH THROUGH THE NATIONAL RISK MANAGEMENT RESEARCH LABORATORY (NRMRL)

EPA Science Inventory

The Ecosystem Restoration Research Program underway through ORD's National Risk Management Research Laboratory (NRMRL) has the long-term goal of providing watershed managers with "..state-of-the-science field-evaluated tools, technical guidance, and decision-support systems for s...

Research Politics: Some Issues in Conducting Research for Government as a Client

ERIC Educational Resources Information Center

Diko, Nolutho; Bantwini, Bongani D.

2013-01-01

Researchers are guided by their ideological and ethical viewpoints when conducting research. Doing research for government challenges them to confront these ideals head-on. This article explores the uncertain terrain researchers sometimes have to negotiate when conducting research for government, and discusses relations between researchers and…

The Air Force Research Laboratory’s In-Space Propulsion Program

DTIC Science & Technology

2015-02-01

Air Force Research Laboratory (AFMC) AFRL /RQRS 1 Ara...MONITOR’S ACRONYM(S) Air Force Research Laboratory (AFMC) AFRL /RQR 5 Pollux Drive 11. SPONSOR/MONITOR’S REPORT Edwards AFB CA 93524-7048 NUMBER(S) AFRL ...illustrate the rationale behind AFRL’s technology development strategy. INTRODUCTION The Air Force Research Laboratory ( AFRL ) is the technology

NASA Ames Fluid Mechanics Laboratory research briefs

NASA Technical Reports Server (NTRS)

Davis, Sanford (Editor)

1994-01-01

The Ames Fluid Mechanics Laboratory research program is presented in a series of research briefs. Nineteen projects covering aeronautical fluid mechanics and related areas are discussed and augmented with the publication and presentation output of the Branch for the period 1990-1993.

History | Frederick National Laboratory for Cancer Research

Cancer.gov

The Frederick National Laboratory for Cancer Research was established as the Frederick Cancer Research and Development Center in 1972 when about 70 acres and 67 buildings of the U.S. Army were transferred to the U.S. Department of Health and Huma

US Army Research Laboratory and University of Notre Dame Distributed Sensing: Hardware Overview

DTIC Science & Technology

2017-11-01

ARL-TR-8199 ● NOV 2017 US Army Research Laboratory US Army Research Laboratory and University of Notre Dame Distributed Sensing...US Army Research Laboratory US Army Research Laboratory and University of Notre Dame Distributed Sensing: Hardware Overview by Roger P...TITLE AND SUBTITLE US Army Research Laboratory and University of Notre Dame Distributed Sensing: Hardware Overview 5a. CONTRACT NUMBER 5b. GRANT

Ten steps to conducting health professional education research.

PubMed

Scott, Karen; Caldwell, Patrina; Schuwirth, Lambert

2015-08-01

The approaches used to educate future clinicians must be continually improved through evidence-based methods. Clinicians interested in conducting education research need to understand the terminology and conventions of health professional education, in the same way that health professional educators from education backgrounds need to be aware of clinical practices and scientific mores and jargon. This article provides clinicians with 10 steps to conducting health professional education research, and encourages collaboration between clinicians interested in education and health professional educators. The basic steps in conducting education research are introduced, beginning with literature searches, using appropriate terminology and writing conventions, and finding research collaborators. We encourage researchers to ask themselves, 'So what?' about their research idea to ensure it is interesting and relevant to a journal's readers. The nuts and bolts of educational research are then presented, including research questions and methodologies, outcome measures, theoretical frameworks and epistemologies. The final two steps aim to foster internationally relevant and well-designed research studies. Conducting and publishing education research is often difficult for clinicians, who struggle with what is required. Yet clinicians who teach are ideally placed to identify the knowledge gaps about how we can more effectively educate future clinicians. These 10 steps provide clinicians with guidance on how to conduct education research so relevant research findings can inform the education of future clinicians. Conducting and publishing education research is often difficult for clinicians. © 2015 John Wiley & Sons Ltd.

Bringing the excitement and motivation of research to students; Using inquiry and research-based learning in a year-long biochemistry laboratory : Part II-research-based laboratory-a semester-long research approach using malate dehydrogenase as a research model.

PubMed

Knutson, Kristopher; Smith, Jennifer; Nichols, Paul; Wallert, Mark A; Provost, Joseph J

2010-09-01

Research-based learning in a teaching environment is an effective way to help bring the excitement and experience of independent bench research to a large number of students. The program described here is the second of a two-semester biochemistry laboratory series. Here, students are empowered to design, execute and analyze their own experiments for the entire semester. This style of laboratory replaces a variety of shorter labs in favor of an in depth research-based learning experience. The concept is to allow students to function in independent research groups. The research projects are focused on a series of wild-type and mutant clones of malate dehydrogenase. A common research theme for the laboratory helps instructors administer the course and is key to delivering a research opportunity to a large number of students. The outcome of this research-based learning laboratory results in students who are much more confident and skilled in critical areas in biochemistry and molecular biology. Students with research experience have significantly higher confidence and motivation than those students without a previous research experience. We have also found that all students performed better in advanced courses and in the workplace. Copyright © 2010 International Union of Biochemistry and Molecular Biology, Inc.

Life Sciences Laboratories for the Shuttle/Spacelab

NASA Technical Reports Server (NTRS)

Schulte, L. O.; Kelly, H. B.; Secord, T. C.

1976-01-01

Space Shuttle and Spacelab missions will provide scientists with their first opportunity to participate directly in research in space for all scientific disciplines, particularly the Life Sciences. Preparations are already underway to ensure the success of these missions. The paper summarizes the results of the 1975 NASA-funded Life Sciences Laboratories definition study which defined several long-range life sciences research options and the laboratory designs necessary to accomplish high-priority life sciences research. The implications and impacts of Spacelab design and development on the life sciences missions are discussed. An approach is presented based upon the development of a general-purposs laboratory capability and an inventory of common operational research equipment for conducting life sciences research. Several life sciences laboratories and their capabilities are described to demonstrate the systems potentially available to the experimenter for conducting biological and medical research.

MSU-DOE Plant Research Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-01-01

This document is the compiled progress reports of research funded through the Michigan State University/Department of Energy Plant Research Laboratory. Fourteen reports are included, covering the molecular basis of plant/microbe symbiosis, cell wall biosynthesis and proteins, gene expression, stress responses, plant hormone biosynthesis, interactions between the nuclear and organelle genomes, sensory transduction and tropisms, intracellular sorting and trafficking, regulation of lipid metabolism, molecular basis of disease resistance and plant pathogenesis, developmental biology of Cyanobacteria, and hormonal involvement in environmental control of plant growth. 320 refs., 26 figs., 3 tabs. (MHB)

Savannah River Ecology Laboratory. Annual technical progress report of ecological research, period ending July 31, 1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-07-31

The Savannah River Ecology Laboratory (SREL) is a research unit of the University of Georgia (UGA) that is managed in conjunction with the University`s Institute of Ecology. The laboratory`s overall mission is to acquire and communicate knowledge of ecological processes and principles. SREL conducts basic and applied ecological research, as well as education and outreach programs, under an M&O contract with the US Department of Energy at the Savannah River Site. Significant accomplishments were made during the year ending July 31, 1994 in the areas of research, education and service. Reviewed in this document are research projects in the followingmore » areas: Environmental Operations Support (impacted wetlands, streams, trace organics, radioecology, database synthesis, wild life studies, zooplankton, safety and quality assurance); wood stork foraging and breeding ecology; defence waste processing facility; environmental risk assessment (endangered species, fish, ash basin studies); ecosystem alteration by chemical pollutants; wetlands systems; biodiversity on the SRS; Environmental toxicology; environmental outreach and education; Par Pond drawdown studies in wildlife and fish and metals; theoretical ecology; DOE-SR National Environmental Research Park; wildlife studies. Summaries of educational programs and publications are also give.« less

Laboratory directed research and development program FY 1999

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hansen, Todd; Levy, Karin

2000-03-08

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operatemore » unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. This is the annual report on Laboratory Directed Research and Development (LDRD) program for FY99.« less

Low-gravity Orbiting Research Laboratory Environment Potential Impact on Space Biology Research

NASA Technical Reports Server (NTRS)

Jules, Kenol

2006-01-01

One of the major objectives of any orbital space research platform is to provide a quiescent low gravity, preferably a zero gravity environment, to perform fundamental as well as applied research. However, small disturbances exist onboard any low earth orbital research platform. The impact of these disturbances must be taken into account by space research scientists during their research planning, design and data analysis in order to avoid confounding factors in their science results. The reduced gravity environment of an orbiting research platform in low earth orbit is a complex phenomenon. Many factors, among others, such as experiment operations, equipment operation, life support systems and crew activity (if it is a crewed platform), aerodynamic drag, gravity gradient, rotational effects as well as the vehicle structural resonance frequencies (structural modes) contribute to form the overall reduced gravity environment in which space research is performed. The contribution of these small disturbances or accelerations is precisely why the environment is NOT a zero gravity environment, but a reduced acceleration environment. This paper does not discuss other factors such as radiation, electromagnetic interference, thermal and pressure gradient changes, acoustic and CO2 build-up to name a few that affect the space research environment as well, but it focuses solely on the magnitude of the acceleration level found on orbiting research laboratory used by research scientists to conduct space research. For ease of analysis this paper divides the frequency spectrum relevant to most of the space research disciplines into three regimes: a) quasi-steady, b) vibratory and c) transient. The International Space Station is used as an example to illustrate the point. The paper discusses the impact of these three regimes on space biology research and results from space flown experiments are used to illustrate the potential negative impact of these disturbances (accelerations

Laboratory Directed Research and Development annual report, fiscal year 1997

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-03-01

The Department of Energy Order 413.2(a) establishes DOE`s policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. As described in 413.2, LDRD is research and development of a creative and innovative nature which is selected by the Laboratory Director or his or her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory and to respond to scientific and technological opportunities in conformance with the guidelines in this Order. DOE Order 413.2 requires that each laboratory submit an annual report on its LDRD activities to the cognizant Secretarial Officer through themore » appropriate Operations Office Manager. The report provided in this document represents Pacific Northwest National Laboratory`s LDRD report for FY 1997.« less

24. PHOTOCOPY OF PLAN DRAWING. Quartermaster Research and Development Laboratory, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

24. PHOTOCOPY OF PLAN DRAWING. Quartermaster Research and Development Laboratory, Natick, Mass, Climatic Building, First Floor Plan, Architectural. Drawing No. 35-07-01, Sheet 2 of 72, 1952, updated to 1985. (Source: NRDEC). - Natick Research & Development Laboratories, Climatic Chambers Building, U.S. Army Natick Research, Development & Engineering Center (NRDEC), Natick, Middlesex County, MA

25. PHOTOCOPY OF PLAN DRAWING. Quartermaster Research and Development Laboratory, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

25. PHOTOCOPY OF PLAN DRAWING. Quartermaster Research and Development Laboratory, Natick, Mass. Climatic Building, First Floor Plan, Refrigeration and Engineering. Drawing No. 35-07-01, Sheet 52 of 72, 1952. (Source: NRDEC). - Natick Research & Development Laboratories, Climatic Chambers Building, U.S. Army Natick Research, Development & Engineering Center (NRDEC), Natick, Middlesex County, MA

Laboratory Directed Research and Development FY2008 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kammeraad, J E; Jackson, K J; Sketchley, J A

The Laboratory Directed Research and Development (LDRD) Program, authorized by Congress in 1991 and administered by the Institutional Science and Technology Office at Lawrence Livermore, is our primary means for pursuing innovative, long-term, high-risk, and potentially high-payoff research that supports the full spectrum of national security interests encompassed by the missions of the Laboratory, the Department of Energy, and National Nuclear Security Administration. The accomplishments described in this annual report demonstrate the strong alignment of the LDRD portfolio with these missions and contribute to the Laboratory's success in meeting its goals. The LDRD budget of $91.5 million for fiscal yearmore » 2008 sponsored 176 projects. These projects were selected through an extensive peer-review process to ensure the highest scientific quality and mission relevance. Each year, the number of deserving proposals far exceeds the funding available, making the selection a tough one indeed. Our ongoing investments in LDRD have reaped long-term rewards for the Laboratory and the nation. Many Laboratory programs trace their roots to research thrusts that began several years ago under LDRD sponsorship. In addition, many LDRD projects contribute to more than one mission area, leveraging the Laboratory's multidisciplinary team approach to science and technology. Safeguarding the nation from terrorist activity and the proliferation of weapons of mass destruction will be an enduring mission of this Laboratory, for which LDRD will continue to play a vital role. The LDRD Program is a success story. Our projects continue to win national recognition for excellence through prestigious awards, papers published in peer-reviewed journals, and patents granted. With its reputation for sponsoring innovative projects, the LDRD Program is also a major vehicle for attracting and retaining the best and the brightest technical staff and for establishing collaborations with universities

Sandia, California Tritium Research Laboratory transition and reutilization project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garcia, T.B.

1997-02-01

This paper describes a project within Sandia National Laboratory to convert the shut down Tritium Research Laboratory into a facility which could be reused within the laboratory complex. In the process of decommissioning and decontaminating the facility, the laboratory was able to save substantial financial resources by transferring much existing equipment to other DOE facilities, and then expeditiously implementing a decontamination program which has resulted in the building being converted into laboratory space for new lab programs. This project of facility reuse has been a significant financial benefit to the laboratory.

Sandia National Laboratories: Visiting Research Scholars

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

A Counsellor's Guide to Conducting Psychobiographical Research

ERIC Educational Resources Information Center

Ponterotto, Joseph G.

2017-01-01

By nature of their interests and professional training, counsellors are ideally equipped to conduct psychobiographical research. This article positions the counselling field in the broad specialty area of psychobiography, highlights the preparedness of counsellors to conduct psychobiographical research, and emphasizes the benefits of this research…

Participatory Action Research as a Model for Conducting Family Research.

ERIC Educational Resources Information Center

Turnbull, Ann P.; Friesen, Barbara J.; Ramirez, Carmen

1998-01-01

This article discusses a participatory action research (PAR) approach to conducting family research. It proposes a model of PAR implementation level including the options of family members as research leaders and researchers as ongoing advisors, researchers and family members as coresearchers, and researches as leaders, and family members as…

Frederick National Laboratory Scientists to Present Advanced Technologies in Cancer Research | Frederick National Laboratory for Cancer Research

Cancer.gov

FREDERICK, Md. -- Hundreds of science and business professionals are expected to attend the second annual Technology Showcase at the Frederick National Laboratory for Cancer Research, scheduled for June 13.  The event will feature technologies bei

United States Air Force Summer Research Program -- 1993. Volume 8. Phillips Laboratory

DTIC Science & Technology

1993-12-01

Research Program Phillips Laboratory Kirtland Air Force Base Albuquerque. New Mexico Sponsored by...Best Available Copy UNITED STATES AIR FORCE SUMMER RESEARCH PROGRAM -- 1993 SUMMER RESEARCH PROGRAM FINAL REPORTS VOLUME 8 PHILLIPS LABORATORY ...Alabama Box 870344 Tuscaloosa, AL 35487-0344 Final Report for: Graduate Student Research Program Phillips Laboratory , Hanscom AFB Sponsored by: Air

RIPOSTE: a framework for improving the design and analysis of laboratory-based research

PubMed Central

Masca, Nicholas GD; Hensor, Elizabeth MA; Cornelius, Victoria R; Buffa, Francesca M; Marriott, Helen M; Eales, James M; Messenger, Michael P; Anderson, Amy E; Boot, Chris; Bunce, Catey; Goldin, Robert D; Harris, Jessica; Hinchliffe, Rod F; Junaid, Hiba; Kingston, Shaun; Martin-Ruiz, Carmen; Nelson, Christopher P; Peacock, Janet; Seed, Paul T; Shinkins, Bethany; Staples, Karl J; Toombs, Jamie; Wright, Adam KA; Teare, M Dawn

2015-01-01

Lack of reproducibility is an ongoing problem in some areas of the biomedical sciences. Poor experimental design and a failure to engage with experienced statisticians at key stages in the design and analysis of experiments are two factors that contribute to this problem. The RIPOSTE (Reducing IrreProducibility in labOratory STudiEs) framework has been developed to support early and regular discussions between scientists and statisticians in order to improve the design, conduct and analysis of laboratory studies and, therefore, to reduce irreproducibility. This framework is intended for use during the early stages of a research project, when specific questions or hypotheses are proposed. The essential points within the framework are explained and illustrated using three examples (a medical equipment test, a macrophage study and a gene expression study). Sound study design minimises the possibility of bias being introduced into experiments and leads to higher quality research with more reproducible results. DOI: http://dx.doi.org/10.7554/eLife.05519.001 PMID:25951517

RIPOSTE: a framework for improving the design and analysis of laboratory-based research.

PubMed

Masca, Nicholas Gd; Hensor, Elizabeth Ma; Cornelius, Victoria R; Buffa, Francesca M; Marriott, Helen M; Eales, James M; Messenger, Michael P; Anderson, Amy E; Boot, Chris; Bunce, Catey; Goldin, Robert D; Harris, Jessica; Hinchliffe, Rod F; Junaid, Hiba; Kingston, Shaun; Martin-Ruiz, Carmen; Nelson, Christopher P; Peacock, Janet; Seed, Paul T; Shinkins, Bethany; Staples, Karl J; Toombs, Jamie; Wright, Adam Ka; Teare, M Dawn

2015-05-07

Lack of reproducibility is an ongoing problem in some areas of the biomedical sciences. Poor experimental design and a failure to engage with experienced statisticians at key stages in the design and analysis of experiments are two factors that contribute to this problem. The RIPOSTE (Reducing IrreProducibility in labOratory STudiEs) framework has been developed to support early and regular discussions between scientists and statisticians in order to improve the design, conduct and analysis of laboratory studies and, therefore, to reduce irreproducibility. This framework is intended for use during the early stages of a research project, when specific questions or hypotheses are proposed. The essential points within the framework are explained and illustrated using three examples (a medical equipment test, a macrophage study and a gene expression study). Sound study design minimises the possibility of bias being introduced into experiments and leads to higher quality research with more reproducible results.

Increasing value and reducing waste in research design, conduct, and analysis.

PubMed

Ioannidis, John P A; Greenland, Sander; Hlatky, Mark A; Khoury, Muin J; Macleod, Malcolm R; Moher, David; Schulz, Kenneth F; Tibshirani, Robert

2014-01-11

Correctable weaknesses in the design, conduct, and analysis of biomedical and public health research studies can produce misleading results and waste valuable resources. Small effects can be difficult to distinguish from bias introduced by study design and analyses. An absence of detailed written protocols and poor documentation of research is common. Information obtained might not be useful or important, and statistical precision or power is often too low or used in a misleading way. Insufficient consideration might be given to both previous and continuing studies. Arbitrary choice of analyses and an overemphasis on random extremes might affect the reported findings. Several problems relate to the research workforce, including failure to involve experienced statisticians and methodologists, failure to train clinical researchers and laboratory scientists in research methods and design, and the involvement of stakeholders with conflicts of interest. Inadequate emphasis is placed on recording of research decisions and on reproducibility of research. Finally, reward systems incentivise quantity more than quality, and novelty more than reliability. We propose potential solutions for these problems, including improvements in protocols and documentation, consideration of evidence from studies in progress, standardisation of research efforts, optimisation and training of an experienced and non-conflicted scientific workforce, and reconsideration of scientific reward systems. Copyright © 2014 Elsevier Ltd. All rights reserved.

THE U.S. EPA NATIONAL HEALTH AND ENVIRONMENTAL EFFECTS RESEARCH LABORATORY'S APPROACH TO AUDITING HEALTH EFFECTS STUDIES

EPA Science Inventory

This is an abstract of a proposed presentation and does not necessarily reflect EPA policy.

The Health Divisions of the US EPA National Health and Environmental Effects Research Laboratory have a guideline for conducting technical systems audits. As part of the guideline ...

QUALITY ASSURANCE IN RESEARCH LABORATORIES: RULES AND REASON

EPA Science Inventory

Quality Assurance in Research Laboratories: Rules and Reason

Ron Rogers, Quality Assurance and Records Manager, Environmental Carcinogenesis Division, NHEERL/ORD/US EPA, Research Triangle Park, NC, 27709

To anyone who has actively participated in research, as I have...

Laboratory Directed Research and Development Program FY98

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hansen, T.; Chartock, M.

1999-02-05

The Ernest Orlando Lawrence Berkeley National Laboratory (LBNL or Berkeley Lab) Laboratory Directed Research and Development Program FY 1998 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the supported projects and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The LBNL LDRD program is a critical tool for directing the Laboratory's forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program providesmore » the resources for LBNL scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also advances LBNL's core competencies, foundations, and scientific capability, and permits exploration of exciting new opportunities. All projects are work in forefront areas of science and technology. Areas eligible for support include the following: Advanced study of hypotheses, concepts, or innovative approaches to scientific or technical problems; Experiments and analyses directed toward ''proof of principle'' or early determination of the utility of new scientific ideas, technical concepts, or devices; and Conception and preliminary technical analyses of experimental facilities or devices.« less

A geophysical perspective on mantle water content and melting: Inverting electromagnetic sounding data using laboratory-based electrical conductivity profiles

NASA Astrophysics Data System (ADS)

Khan, A.; Shankland, T. J.

2012-02-01

This paper applies electromagnetic sounding methods for Earth's mantle to constrain its thermal state, chemical composition, and "water" content. We consider long-period inductive response functions in the form of C-responses from four stations distributed across the Earth (Europe, North America, Asia and Australia) covering a period range from 3.9 to 95.2 days and sensitivity to ~ 1200 km depth. We invert C-responses directly for thermo-chemical state using a self-consistent thermodynamic method that computes phase equilibria as functions of pressure, temperature, and composition (in the Na2O-CaO-FeO-MgO-Al2O3-SiO2 model system). Computed mineral modes are combined with recent laboratory-based electrical conductivity models from independent experimental research groups (Yoshino (2010) and Karato (2011)) to compute bulk conductivity structure beneath each of the four stations from which C-responses are estimated. To reliably allocate water between the various mineral phases we include laboratory-measured water partition coefficients for major upper mantle and transition zone minerals. This scheme is interfaced with a sampling-based algorithm to solve the resulting non-linear inverse problem. This approach has two advantages: (1) It anchors temperatures, composition, electrical conductivities, and discontinuities that are in laboratory-based forward models, and (2) At the same time it permits the use of geophysical inverse methods to optimize conductivity profiles to match geophysical data. The results show lateral variations in upper mantle temperatures beneath the four stations that appear to persist throughout the upper mantle and parts of the transition zone. Calculated mantle temperatures at 410 and 660 km depth lie in the range 1250-1650 °C and 1500-1750 °C, respectively, and generally agree with the experimentally-determined temperatures at which the measured phase reactions olivine → β-spinel and γ-spinel → ferropericlase + perovskite occur. The

Alternative Fuels Research Laboratory

NASA Technical Reports Server (NTRS)

Surgenor, Angela D.; Klettlinger, Jennifer L.; Nakley, Leah M.; Yen, Chia H.

2012-01-01

NASA Glenn has invested over $1.5 million in engineering, and infrastructure upgrades to renovate an existing test facility at the NASA Glenn Research Center (GRC), which is now being used as an Alternative Fuels Laboratory. Facility systems have demonstrated reliability and consistency for continuous and safe operations in Fischer-Tropsch (F-T) synthesis and thermal stability testing. This effort is supported by the NASA Fundamental Aeronautics Subsonic Fixed Wing project. The purpose of this test facility is to conduct bench scale F-T catalyst screening experiments. These experiments require the use of a synthesis gas feedstock, which will enable the investigation of F-T reaction kinetics, product yields and hydrocarbon distributions. Currently the facility has the capability of performing three simultaneous reactor screening tests, along with a fourth fixed-bed reactor for catalyst activation studies. Product gas composition and performance data can be continuously obtained with an automated gas sampling system, which directly connects the reactors to a micro-gas chromatograph (micro GC). Liquid and molten product samples are collected intermittently and are analyzed by injecting as a diluted sample into designated gas chromatograph units. The test facility also has the capability of performing thermal stability experiments of alternative aviation fuels with the use of a Hot Liquid Process Simulator (HLPS) (Ref. 1) in accordance to ASTM D 3241 "Thermal Oxidation Stability of Aviation Fuels" (JFTOT method) (Ref. 2). An Ellipsometer will be used to study fuel fouling thicknesses on heated tubes from the HLPS experiments. A detailed overview of the test facility systems and capabilities are described in this paper.

United States Air Force Summer Research Program -- 1993. Volume 13. Phillips Laboratory

DTIC Science & Technology

1993-12-01

Research Kirtland Air Force Base, Albuquerque, NM August 1993 14-1 My Summer Apprenticeship At Kirtland Air Force Base, Phillips Laboratory Andrea Garcia...AFOSR Summer Research Program Phillips Laboratory Sponsored By: Air Force Office of Scientific Research Kirtland Air Force Base, Albuquerque, NM... Phillips Laboratory Sponsored by: Air

United States Air Force Summer Research Program -- 1993. Volume 3. Phillips Laboratory

DTIC Science & Technology

1993-12-01

PHILLIPS LABORATORY KIRTLAND AIR FORCE BASE, NEW MEXICO SPONSORED BY: AIR FORCE OFFICE OF SCIENTIFIC RESEARCH ROLLING AIR FORCE BASE, WASHINGTON ,D.C...Report for. Summer Faculty Research Program at Phillips Laboratory Kirtland Air Force Base Sponsored by: Air Force Offlce of Scientific Research ...Prcgram Phillips Laboratory Kirtland

Improving Students' Inquiry Skills and Self-Efficacy through Research-Inspired Modules in the General Chemistry Laboratory

ERIC Educational Resources Information Center

Winkelmann, Kurt; Baloga, Monica; Marcinkowski, Tom; Giannoulis, Christos; Anquandah, George; Cohen, Peter

2015-01-01

Research projects conducted by faculty in STEM departments served as the inspiration for a new curriculum of inquiry-based, multiweek laboratory modules in the general chemistry 1 course. The purpose of this curriculum redesign was to improve students' attitudes about chemistry as well as their self-efficacy and skills in performing inquiry…

2014 Fermilab Laboratory Directed Research & Development Program Plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wester, W., editor

2016-05-26

Fermilab is executing Laboratory Directed Research and Development (LDRD) as outlined by order DOE O 413.2B in order to enhance and realize the mission of the laboratory in a manner that also supports the laboratory’s strategic objectives and the mission of the Department of Energy. LDRD funds enable scientific creativity, allow for exploration of “high risk, high payoff” research, and allow for the demonstration of new ideas, technical concepts, and devices. LDRD also has an objective of maintaining and enhancing the scientific and technical vitality of Fermilab.

U.S. Army Aeromedical Research Laboratory Annual Progress Report: FY 84

DTIC Science & Technology

1984-10-01

OFFICE SYMBOL 7a. NAME OF MONITORING ORGANIZATION U.S. Army Aeromedical Research (if applicable) U.S. Army Medical Research and Developmmt Laboratory...Group for Aerospace Research and Develop- ment--Aerospace Medical Panel ......................... 105 American National Standards Institute (ANSI...aviation specialities. Assists other US Army Medical Research and Development Command (USAMRDC) laboratories and institutes in research on the

NASA Johnson Space Center's Planetary Sample Analysis and Mission Science (PSAMS) Laboratory: A National Facility for Planetary Research

NASA Technical Reports Server (NTRS)

Draper, D. S.

2016-01-01

NASA Johnson Space Center's (JSC's) Astromaterials Research and Exploration Science (ARES) Division, part of the Exploration Integration and Science Directorate, houses a unique combination of laboratories and other assets for conducting cutting edge planetary research. These facilities have been accessed for decades by outside scientists, most at no cost and on an informal basis. ARES has thus provided substantial leverage to many past and ongoing science projects at the national and international level. Here we propose to formalize that support via an ARES/JSC Plane-tary Sample Analysis and Mission Science Laboratory (PSAMS Lab). We maintain three major research capa-bilities: astromaterial sample analysis, planetary process simulation, and robotic-mission analog research. ARES scientists also support planning for eventual human ex-ploration missions, including astronaut geological training. We outline our facility's capabilities and its potential service to the community at large which, taken together with longstanding ARES experience and expertise in curation and in applied mission science, enable multi-disciplinary planetary research possible at no other institution. Comprehensive campaigns incorporating sample data, experimental constraints, and mission science data can be conducted under one roof.

PUBLICATIONS; GULF BREEZE LABORATORY

EPA Science Inventory

The bibliography, inclusive from 1967 through 1978, lists all publications authored by researchers employed by the Environmental Research Laboratory, Gulf Breeze, and its field station on St. Johns Island, SC, or by researchers conducting studies under funding or direction of the...

Visiting Scholars Program | Frederick National Laboratory for Cancer Research

Cancer.gov

The Visiting Scholars Program (VSP) provides a unique opportunity for scientists to collaborate with the Frederick National Laboratory for Cancer Research (FNLCR), the only federal national laboratory in the United States devoted exclusively to b

Draftsmen at Work during Construction of the Aircraft Engine Research Laboratory

NASA Image and Video Library

1942-09-21

The National Advisory Committee for Aeronautics (NACA) Aircraft Engine Research Laboratory was designed by a group of engineers at the Langley Memorial Aeronautical Laboratory in late 1940 and 1941. Under the guidance of Ernest Whitney, the men worked on drawings and calculations in a room above Langley’s Structural Research Laboratory. The main Aircraft Engine Research Laboratory design group originally consisted of approximately 30 engineers and draftsmen, but there were smaller groups working separately on specific facilities. The new engine lab would have six principal buildings: the Engine Research Building, hangar, Fuels and Lubricants Building, Administration Building, Propeller Test Stand, and Altitude Wind Tunnel. In December 1941 most of those working on the project transferred to Cleveland from Langley. Harrison Underwood and Charles Egan led 18 architectural, 26 machine equipment, 3 structural and 10 mechanical draftsmen. Initially these staff members were housed in temporary offices in the hangar. As sections of the four-acre Engine Research Building were completed in the summer of 1942, the design team began relocating there. The Engine Research Building contained a variety of test cells and laboratories to address virtually every aspect of piston engine research. It also contained a two-story office wing, seen in this photograph that would later house many of the powerplant research engineers.

Kathleen Igo | Frederick National Laboratory for Cancer Research

Cancer.gov

Directorate: Clinical Research Program Department or lab: Clinical Monitoring Research Program (CMRP) How many years have you worked at the Frederick National Laboratory? I am in my 7th year of employment.

ORNLs Laboratory Directed Research and Development Program FY 2009 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2010-03-01

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2009. The associated FY 2009 ORNL LDRD Self-Assessment (ORNL/PPA-2010/2) provides financial data andmore » an internal evaluation of the program’s management process.« less

ORNLs Laboratory Directed Research and Development Program FY 2013 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2014-03-01

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the US Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2013. The associated FY 2013 ORNL LDRD Self-Assessment (ORNL/PPA-2014/2) provides financial datamore » and an internal evaluation of the program’s management process.« less

ORNLs Laboratory Directed Research and Development Program FY 2008 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2009-03-01

The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2008. The associated FY 2008 ORNL LDRD Self-Assessment (ORNL/PPA-2008/2) provides financial data and anmore » internal evaluation of the program’s management process.« less

ORNLs Laboratory Directed Research and Development Program FY 2012 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2013-03-01

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the US Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2012. The associated FY 2012 ORNL LDRD Self-Assessment (ORNL/PPA-2012/2) provides financial datamore » and an internal evaluation of the program’s management process.« less

Going GLP: Conducting Toxicology Studies in Compliance with Good Laboratory Practices.

PubMed

Carroll, Erica Eggers

2016-01-01

Good laboratory practice standards are US federal regulations enacted as part of the Federal Insecticide, Fungicide, and Rodenticide Act (40 CFR Part 160), the Toxic Substance Control Act (40 CFR Part 792), and the Good Laboratory Practice for Nonclinical Laboratory Studies (21 CFR Part 58) to support protection of public health in the areas of pesticides, chemicals, and drug investigations in response to allegations of inaccurate data acquisition. Essentially, good laboratory practices (GLPs) are a system of management controls for nonclinical research studies involving animals to ensure the uniformity, consistency, reliability, reproducibility, quality, and integrity of data collected as part of chemical (including pharmaceuticals) tests, from in vitro through acute to chronic toxicity tests. The GLPs were established in the United States in 1978 as a result of the Industrial Bio-Test Laboratory scandal which led to congressional hearings and actions to prevent fraudulent data reporting and collection. Although the establishment of infrastructure for GLPs compliance is labor-intensive and time-consuming, achievement and maintenance of GLP compliance ensures the accuracy of the data collected from each study, which is critical for defending results, advancing science, and protecting human and animal health. This article describes how and why those in the US Army Medical Department responsible for protecting the public health of US Army and other military personnel made the policy decision to have its toxicology laboratory achieve complete compliance with GLP standards, the first such among US Army laboratories. The challenges faced and how they were overcome are detailed.

Air Force Officers Visit Aircraft Engine Research Laboratory

NASA Image and Video Library

1945-08-21

A group of 60 Army Air Forces officers visited the National Advisory Committee for Aeronautics (NACA) Aircraft Engine Research Laboratory on August 27, 1945. The laboratory enacted strict security regulations throughout World War II. During the final months of the war, however, the NACA began opening its doors to groups of writers, servicemen, and aviation industry leaders. These events were the first exposure of the new engine laboratory to the outside world. Grandstands were built alongside the Altitude Wind Tunnel specifically for group photographs. George Lewis, Raymond Sharp, and Addison Rothrock (right to left) addressed this group of officers in the Administration Building auditorium. Lewis was the NACA’s Director of Aeronautical Research, Sharp was the lab’s manager, and Rothrock was the lab’s chief of research. Abe Silverstein, Jesse Hall and others watch from the rear of the room. The group toured several facilities after the talks, including the Altitude Wind Tunnel and a new small supersonic wind tunnel. The visit concluded with a NACA versus Army baseball game and cookout.

Lessons learned from conducting qualitative research in a hospital.

PubMed

Woith, Wendy Mann; Jenkins, Sheryl Henry; Astroth, Kim Schafer; Kennedy, Julie A

2014-11-01

To examine unexpected barriers to the conduct of hospital research during a study of nurses' activation of rapid response teams. We interviewed hospital nurses regarding their decisions to activate rapid response teams and encountered unexpected barriers to the conduct of this study in the hospital setting. Experience of conducting qualitative research with bedside nurses in a community hospital. Review of the reports of others who have conducted hospital research. Barriers related to administrative support, environmental distractors, constraints on nurses' time, apparent lack of investment in research by staff and a cumbersome recruitment process are identified. Recommendations on study site selection, timing of research, gaining access to nurses, scheduling and conducting interviews, and transcribing recorded data are made. As evidence is necessary to deliver safe, quality care, it is important that nurses understand and participate in research. This participation involves not only conducting research, but also serving as subjects. Given the importance of bedside nurses' willingness to engage in research, it is crucial to understand factors that impede or assist their participation. We offer several recommendations to nurses conducting research in hospitals, including: ■ Seek hospitals that are supportive of research, yet not over-invested in the process. ■ Build extra time into data collection schedules to maximize flexibility and accommodate work-place demands. ■ Emphasise the relevance and benefits of the research to nurses.

Laboratory Directed Research and Development FY 2000 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Al-Ayat, R

This Annual Report provides an overview of the FY2000 Laboratory Directed Research and Development (LDRD) Program at Lawrence Livermore National Laboratory (LLNL) and presents a summary of the results achieved by each project during the year.

US Army Research Laboratory and University of Notre Dame Distributed Sensing: Software Overview

DTIC Science & Technology

2017-09-01

ARL-TN-0847 ● Sep 2017 US Army Research Laboratory US Army Research Laboratory and University of Notre Dame Distributed Sensing...Destroy this report when it is no longer needed. Do not return it to the originator. ARL-TN-0847 ● Sep 2017 US Army Research Laboratory...US Army Research Laboratory and University of Notre Dame Distributed Sensing: Software Overview by Neal Tesny Sensors and Electron Devices

Summer Research Program (1992). Summer Faculty Research Program (SFRP) Reports. Volume 5A. Wright Laboratory

DTIC Science & Technology

1992-12-01

1992 6-~1 SOME RESULTS IN MACIIINE- LEARNING Mike Breen Assistant Professor Department of Mathematics Tennessee Technological Universitv Abstract The...Research Laboratory; Wilford Hall Medical Center 12 High School Apprenticeship Program Reports: Armstrong Laboratory 13 High School Apprenticeship ...Program Reports: Phillips Laboratory 14 High School Apprenticeship Program Reports: Rome Laboratory 15 High School Apprenticeship Program Reports

Laboratory-Directed Research and Development 2016 Summary Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pillai, Rekha Sukamar; Jacobson, Julie Ann

The Laboratory-Directed Research and Development (LDRD) Program at Idaho National Laboratory (INL) reports its status to the U.S. Department of Energy (DOE) by March of each year. The program operates under the authority of DOE Order 413.2C, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the laboratory director broad flexibility for program implementation. LDRD funds are obtained through a charge to all INL programs. This report includes summaries of all INL LDRD research activities supported during Fiscal Year (FY) 2016. INL is the lead laboratory for the DOE Office of Nuclearmore » Energy (DOE-NE). The INL mission is to discover, demonstrate, and secure innovative nuclear energy solutions, other clean energy options, and critical infrastructure with a vision to change the world’s energy future and secure our critical infrastructure. Operating since 1949, INL is the nation’s leading research, development, and demonstration center for nuclear energy, including nuclear nonproliferation and physical and cyber-based protection of energy systems and critical infrastructure, as well as integrated energy systems research, development, demonstration, and deployment. INL has been managed and operated by Battelle Energy Alliance, LLC (a wholly owned company of Battelle) for DOE since 2005. Battelle Energy Alliance, LLC, is a partnership between Battelle, BWX Technologies, Inc., AECOM, the Electric Power Research Institute, the National University Consortium (Massachusetts Institute of Technology, Ohio State University, North Carolina State University, University of New Mexico, and Oregon State University), and the Idaho university collaborators (i.e., University of Idaho, Idaho State University, and Boise State University). Since its creation, INL’s research and development (R&D) portfolio has broadened with targeted programs supporting national missions to advance nuclear

The Naval Health Research Center Respiratory Disease Laboratory.

PubMed

Ryan, M; Gray, G; Hawksworth, A; Malasig, M; Hudspeth, M; Poddar, S

2000-07-01

Concern about emerging and reemerging respiratory pathogens prompted the development of a respiratory disease reference laboratory at the Naval Health Research Center. Professionals working in this laboratory have instituted population-based surveillance for pathogens that affect military trainees and responded to threats of increased respiratory disease among high-risk military groups. Capabilities of this laboratory that are unique within the Department of Defense include adenovirus testing by viral shell culture and microneutralization serotyping, influenza culture and hemagglutination inhibition serotyping, and other special testing for Streptococcus pneumoniae, Streptococcus pyogenes, Mycoplasma pneumonia, and Chlamydia pneumoniae. Projected capabilities of this laboratory include more advanced testing for these pathogens and testing for other emerging pathogens, including Bordetella pertussis, Legionella pneumoniae, and Haemophilus influenzae type B. Such capabilities make the laboratory a valuable resource for military public health.

Enabling UAS Research at the NASA EAV Laboratory

NASA Technical Reports Server (NTRS)

Ippolito, Corey A.

2015-01-01

The Exploration Aerial Vehicles (EAV) Laboratory at NASA Ames Research Center leads research into intelligent autonomy and advanced control systems, bridging the gap between simulation and full-scale technology through flight test experimentation on unmanned sub-scale test vehicles.

The role of veterinary research laboratories in the provision of veterinary services.

PubMed

Verwoerd, D W

1998-08-01

Veterinary research laboratories play an essential role in the provision of veterinary services in most countries. These laboratories are the source of new knowledge, innovative ideas and improved technology for the surveillance, prevention and control of animal diseases. In addition, many laboratories provide diagnostic and other services. To ensure the optimal integration of various veterinary activities, administrators must understand the functions and constraints of research laboratories. Therefore, a brief discussion is presented of the following: organisational structures methods for developing research programmes outputs of research scientists and how these are measured the management of quality assurance funding of research. Optimal collaboration can only be attained by understanding the environment in which a research scientist functions and the motivational issues at stake.

Senior Research Connects Students with a Living Laboratory As Part of an Integrated Crop and Livestock System

NASA Astrophysics Data System (ADS)

Senturklu, Songul; Landblom, Douglas; Brevik, Eric C.

2015-04-01

highest expenses in beef cattle production. Senior research investigating the impact of livestock integration and multi-species cover crop grown within the crop rotation is studying changes in soil attributes resulting from the crop-animal integration by measuring bulk density and in-season soil fertility in the crop rotation. These responses are further contrasted with results from within the crop rotation and responses from perennial native range. Students that become engaged in the research represent a broad cross section of the consuming public and include high school junior and senior students, college undergraduate students that conduct research projects, postdoctoral research scientists engaged in senior level research, agricultural extension educators, and finally, farmer and rancher businessmen. The integrated nature of the research provides a wealth of learning opportunities for these various groups. For the high school students, visits to the living laboratory increase awareness and introduces students to a potential career path in agriculture, natural resource fields, and the many allied vocational fields that support agriculture. When college undergraduate students visit the living laboratory, they seek to address a researchable question or a problem in agriculture, while fulfilling requirements for graduation by conducting a research project. Because postdoctoral students want to be actively engaged in research and advanced learning, they are interested in conducting research in the living laboratory that can be published in peer reviewed journals. Agricultural extension educators, who advise farmers and ranchers, are looking for research results from the living laboratory that can be convey to their constituents. Farmers and ranchers participate in workshop events that give them face-to-face learning opportunities that they can use to effect change in their farm and ranch businesses. Each of these demographic groups are unique in their interest in the

Conducting interactive experiments online.

PubMed

Arechar, Antonio A; Gächter, Simon; Molleman, Lucas

2018-01-01

Online labor markets provide new opportunities for behavioral research, but conducting economic experiments online raises important methodological challenges. This particularly holds for interactive designs. In this paper, we provide a methodological discussion of the similarities and differences between interactive experiments conducted in the laboratory and online. To this end, we conduct a repeated public goods experiment with and without punishment using samples from the laboratory and the online platform Amazon Mechanical Turk. We chose to replicate this experiment because it is long and logistically complex. It therefore provides a good case study for discussing the methodological and practical challenges of online interactive experimentation. We find that basic behavioral patterns of cooperation and punishment in the laboratory are replicable online. The most important challenge of online interactive experiments is participant dropout. We discuss measures for reducing dropout and show that, for our case study, dropouts are exogenous to the experiment. We conclude that data quality for interactive experiments via the Internet is adequate and reliable, making online interactive experimentation a potentially valuable complement to laboratory studies.

Assessment of three medical and research laboratories using WHO AFRO_SLIPTA Quality Standards in Southwestern Uganda: a long way to go.

PubMed

Taremwa, Ivan Mugisha; Ampaire, Lucas; Iramiot, Jacob; Muhwezi, Obed; Matte, Aloysius; Itabangi, Herbert; Mbabazi, Hope; Atwebembeire, Jeninah; Kamwine, Monicah; Katawera, Victoria; Mbalibulha, Yona; Orikiriza, Patrick; Boum, Yap

2017-01-01

While the laboratory represents more than 70% of clinical diagnosis and patient management, access to reliable and quality laboratory diagnostics in sub-Saharan Africa remains a challenge. To gain knowledge and suggest evidence based interventions towards laboratory improvement in Southwestern Uganda, we assessed the baseline laboratory quality standards in three medical and research laboratories in Southwestern Uganda. We conducted a cross sectional survey from October, 2013 to April, 2014. Selected laboratories, including one private research, one private for profit and one public laboratory, were assessed using the WHO AFRO_SLIPTA checklist and baseline scores were determined. The three laboratories assessed met basic facility requirements, had trained personnel, and safety measures in place. Sample reception was properly designed and executed with a well designated chain of custody. All laboratories had sufficient equipment for the nature of work they were involved in. However, we found that standard operating procedures were incomplete in all three laboratories, lack of quality audit schemes by two laboratories and only one laboratory enrolled into external quality assurance schemes. The SLIPTA scores were one star for the research laboratory and no star for both the public and private-for-profit laboratories. While most of the laboratory systems were in place, the low scores obtained by the assessed laboratories reflect the need for improvement to reach standards of quality assured diagnostics in the region. Therefore, routine mentorship and regional supportive supervision are necessary to increase the quality of laboratory services.

Progress of applied superconductivity research at Materials Research Laboratories, ITRI (Taiwan)

NASA Technical Reports Server (NTRS)

Liu, R. S.; Wang, C. M.

1995-01-01

A status report based on the applied high temperature superconductivity (HTS) research at Materials Research Laboratories (MRL), Industrial Technology Research Institute (ITRI) is given. The aim is to develop fabrication technologies for the high-TC materials appropriate to the industrial application requirements. To date, the majorities of works have been undertaken in the areas of new materials, wires/tapes with long length, prototypes of magnets, large-area thin films, SQUID's and microwave applications.

Savannah River Ecology Laboratory annual technical progress report of ecological research for the year ending July 31, 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, M.H.

1995-07-01

The Savannah River Ecology Laboratory (SREL) is a research unit of the University of Georgia (UGA). The overall mission of the Laboratory is to acquire and communicate knowledge of ecological processes and principles. SREL conducts basic and applied ecological research, as well as education and outreach programs, under a contract with the US Department of Energy (DOE) at the Savannah River Site near Aiken, South Carolina. Significant accomplishments were made during the past year in the areas of research, education and service. Major additions to SREL Facilities were completed that will enhance the Laboratory`s work in the future. Following severalmore » years of planning, opening ceremonies were held for the 5000 ft{sup 2} multi-purpose conference center that was funded by the University of Georgia Research Foundation (UGARF). The center is located on 68 acres of land that was provided by the US Department of Energy. This joint effort between DOE and UGARF supports DOE`s new initiative to develop partnerships with the private sector and universities. The facility is being used for scientific meetings and environmental education programs for students, teachers and the general public. A 6000 ft{sup 2} office and library addition to S@s main building officially opened this year, and construction plans are underway on a new animal care facility, laboratory addition, and receiving building.« less

Aerial View of NACA's Lewis Flight Propulsion Research Laboratory

NASA Image and Video Library

1946-05-21

The National Advisory Committee for Aeronautics (NACA) Lewis Flight Propulsion Laboratory in Cleveland, Ohio as seen from the west in May 1946. The Cleveland Municipal Airport is located directly behind. The laboratory was built in the early 1940s to resolve problems associated with aircraft engines. The initial campus contained seven principal buildings: the Engine Research Building, hangar, Fuels and Lubricants Building, Administration Building, Engine Propeller Research Building, Altitude Wind Tunnel, and Icing Research Tunnel. These facilities and their associated support structures were located within an area occupying approximately one-third of the NACA’s property. After World War II ended, the NACA began adding new facilities to address different problems associated with the newer, more powerful engines and high speed flight. Between 1946 and 1955, four new world-class test facilities were built: the 8- by 6-Foot Supersonic Wind Tunnel, the Propulsion Systems Laboratory, the Rocket Engine Test Facility, and the 10- by 10-Foot Supersonic Wind Tunnel. These large facilities occupied the remainder of the NACA’s semicircular property. The Lewis laboratory expanded again in the late 1950s and early 1960s as the space program commenced. Lewis purchased additional land in areas adjacent to the original laboratory and acquired a large 9000-acre site located 60 miles to the west in Sandusky, Ohio. The new site became known as Plum Brook Station.

49 CFR 40.91 - What validity tests must laboratories conduct on primary specimens?

Code of Federal Regulations, 2011 CFR

2011-10-01

... FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.91 What... testing under § 40.89, you must conduct it in accordance with the requirements of this section. (a) You... responses characteristic of an adulterant obtained during initial or confirmatory drug tests (e.g., non...

49 CFR 40.91 - What validity tests must laboratories conduct on primary specimens?

Code of Federal Regulations, 2012 CFR

2012-10-01

... FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.91 What... testing under § 40.89, you must conduct it in accordance with the requirements of this section. (a) You... responses characteristic of an adulterant obtained during initial or confirmatory drug tests (e.g., non...

49 CFR 40.91 - What validity tests must laboratories conduct on primary specimens?

Code of Federal Regulations, 2010 CFR

2010-10-01

... FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.91 What... testing under § 40.89, you must conduct it in accordance with the requirements of this section. (a) You... responses characteristic of an adulterant obtained during initial or confirmatory drug tests (e.g., non...

49 CFR 40.91 - What validity tests must laboratories conduct on primary specimens?

Code of Federal Regulations, 2014 CFR

2014-10-01

... FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.91 What... testing under § 40.89, you must conduct it in accordance with the requirements of this section. (a) You... responses characteristic of an adulterant obtained during initial or confirmatory drug tests (e.g., non...

49 CFR 40.91 - What validity tests must laboratories conduct on primary specimens?

Code of Federal Regulations, 2013 CFR

2013-10-01

... FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.91 What... testing under § 40.89, you must conduct it in accordance with the requirements of this section. (a) You... responses characteristic of an adulterant obtained during initial or confirmatory drug tests (e.g., non...

America's "undiscovered" laboratory for health services research.

PubMed

Gimbel, Ronald W; Pangaro, Louis; Barbour, Galen

2010-08-01

Debate over reforming the nation's healthcare system has stimulated a need for health services research (HSR) models that are nationally applicable. Toward this end, the authors identify the Military Health System (MHS) as America's "undiscovered" laboratory for HSR. Although many may confuse the MHS with the Department of Veterans Affairs (VA), the 2 systems vary dramatically with respect to their beneficiary populations, access to care, and other important attributes. In this article, the authors describe key characteristics of the MHS including its large beneficiary base, its direct care operating environment, its dedicated medical school and graduate education programs, and its fully operational integrated health information system. Although a few health systems (eg, Kaiser Permanente, Partners Healthcare, and Department of Veterans Affairs) possess some characteristics, no other has all of these components in place. This article sets the stage for contemporary HSR studies with broad applicability to current issues in American healthcare that could be performed within the MHS. Inclusion of the MHS environment in HSR studies of health services delivery modalities, adoption of health information technology, access to care, relationship of medical education to effective safe care delivery, health disparities, child health, and behavioral health would provide strong underpinnings for proposed changes in American healthcare delivery. Finally, the article highlights current regulatory barriers to research within the MHS whereas suggesting steps to minimize their impact in conducting HSR.

Integrating Interdisciplinary Research-Based Experiences in Biotechnology Laboratories

ERIC Educational Resources Information Center

Iyer, Rupa S.; Wales, Melinda E.

2012-01-01

The increasingly interdisciplinary nature of today's scientific research is leading to the transformation of undergraduate education. In addressing these needs, the University of Houston's College of Technology has developed a new interdisciplinary research-based biotechnology laboratory curriculum. Using the pesticide degrading bacterium,…

Towards the responsible conduct of scientific research: is ethics education enough?

PubMed Central

Novossiolova, Tatyana; Sture, Judi

2012-01-01

Much of the discourse on ‘beyond the laboratory door’ biosecurity to date has focused on the need to raise awareness among the scientific community of the risks posed by the rapid advancement of biotechnology in recent decades. While education is undoubtedly important, a growing body of evidence suggests that ethics education does not necessarily translate into ethical behaviour. This trend has already been reported in clinical settings, where research has highlighted doctors’ own reports of ethically dubious practices and challenges when confronted with moral dilemmas in their everyday work. The purpose of this paper is to critically evaluate the practical value of ethics education and show why it is an essential, although insufficient, measure for promoting a culture of responsible conduct of research. We conclude by highlighting the importance of continuing professional development as a way of maintaining life scientists’ engagement with biosecurity issues and supporting them in active roles in the effective implementation of the Biological and Toxin Weapons Convention (BWC). PMID:22606762

Methodological factors conducting research with incarcerated persons with diabetes.

PubMed

Reagan, Louise; Shelton, Deborah

2016-02-01

The aim of this study was to describe methodological issues specific to conducting research with incarcerated vulnerable populations who have diabetes. Much has been written about the ethical and logistical challenges of conducting research with vulnerable incarcerated populations. However, conducting research with incarcerated persons with diabetes is associated with additional issues related to research design, measurement, sampling and recruitment, and data collection procedures. A cross-sectional study examining the relationships of diabetes knowledge, illness representation and self-care behaviors with glycemic control in 124 incarcerated persons was conducted and serves as the basis for describing methodological factors for the conduct of research with an incarcerated population with diabetes. Within this incarcerated population with diabetes, sampling bias due to gender inequity, recruitment of participants not using insulin, self-reported vision impairment, and a lack of standardized instruments especially for measuring diabetes self-care were methodological challenges. Clinical factors that serve as potential barriers for study conduct were identified as risk for hypoglycemia due to insulin timing and other activities. Conducting research with incarcerated persons diagnosed with diabetes requires attention to a set of methodological concerns above and beyond that of the ethical and legal regulations for protecting the rights of this vulnerable population. To increase opportunities for conducting rigorous as well as facility- and patient-friendly research, researchers need to blend their knowledge of diabetes with an understanding of prison rules and routines. Copyright © 2015 Elsevier Inc. All rights reserved.

An overview of Quality Management System implementation in a research laboratory

NASA Astrophysics Data System (ADS)

Molinéro-Demilly, Valérie; Charki, Abdérafi; Jeoffrion, Christine; Lyonnet, Barbara; O'Brien, Steve; Martin, Luc

2018-02-01

The aim of this paper is to show the advantages of implementing a Quality Management System (QMS) in a research laboratory in order to improve the management of risks specific to research programmes and to increase the reliability of results. This paper also presents experience gained from feedback following the implementation of the Quality process in a research laboratory at INRA, the French National Institute for Agronomic Research and details the various challenges encountered and solutions proposed to help achieve smoother adoption of a QMS process. The 7Ms (Management, Measurement, Manpower, Methods, Materials, Machinery, Mother-nature) methodology based on the Ishikawa `Fishbone' diagram is used to show the effectiveness of the actions considered by a QMS, which involve both the organization and the activities of the laboratory. Practical examples illustrate the benefits and improvements observed in the laboratory.

Location | Frederick National Laboratory for Cancer Research

Cancer.gov

The Frederick National Laboratory for Cancer Research campus is located 50 miles northwest of Washington, D.C., and 50 miles west of Baltimore, Maryland, in Frederick, Maryland. Satellite locations include leased and government facilities extending s

Outcomes of a Research-Driven Laboratory and Literature Course Designed to Enhance Undergraduate Contributions to Original Research

ERIC Educational Resources Information Center

Rasche, Madeline E.

2004-01-01

This work describes outcomes of a research-driven advanced microbiology laboratory and literature research course intended to enhance undergraduate preparation for and contributions to original research. The laboratory section was designed to teach fundamental biochemistry and molecular biology techniques in the context of an original research…

NRMRL SCIENCE PUBLICATIONS (NATIONAL RISK MANAGEMENT RESEARCH LABORATORY, EPA, CINCINNATI, OH)

EPA Science Inventory

The National Risk Management Research Laboratory (NRMRL)is the U.S.EPA's center for investigating technological and management approaches for preventing and reducing risks from pollution that threaten human health and the environment. The focus of the Laboratory's research progra...

NASA DC-8 airborne research laboratory

NASA Technical Reports Server (NTRS)

Degreef, Leo H.

1991-01-01

Since the summer of 1987, NASA Ames Research Center has been operating a DC-8 equipped with CFM 56 engines as a flying research laboratory. In this relatively short time, the DC-8, with its tremendous capabilities, has made significant contributions to numerous scientific fields. Capable of staying aloft for over 12 hours, the DC-8 has flown directly over both the North and South Poles, gathering data relating to the ozone hole. Operating from a few thousand feet to over 40,000 feet above sea level the interchangeable payload capability of the DC-8 has made it a versatile scientific tool. The DC-8 also plays a vital role in the development of new satellite-borne sensors as very often those sensors are test-flown on the DC-8 before they are launched into space. The tremendous range and instrument carrying capability make the DC-8 an ideal flying laboratory. A few of the programs the DC-8 has participated in as well as a sampling of the instruments carried are outlined.

Laboratory Directed Research and Development FY 1998 Progress Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

John Vigil; Kyle Wheeler

This is the FY 1998 Progress Report for the Laboratory Directed Research and Development (LDRD) Program at Los Alamos National Laboratory. It gives an overview of the LDRD Program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principle investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic, molecular, optical, and plasma physics, fluids, and particle beams, (5)more » engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.« less

Laboratory directed research and development: FY 1997 progress report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vigil, J.; Prono, J.

1998-05-01

This is the FY 1997 Progress Report for the Laboratory Directed Research and Development (LDRD) program at Los Alamos National Laboratory. It gives an overview of the LDRD program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principal investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic and molecular physics and plasmas, fluids, and particle beams, (5)more » engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.« less

Laboratory Directed Research and Development Program FY2016 Annual Summary of Completed Projects

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

ORNL FY 2016 Annual Summary of Laboratory Directed Research and Development Program (LDRD) Completed Projects. The Laboratory Directed Research and Development (LDRD) program at ORNL operates under the authority of DOE Order 413.2C, “Laboratory Directed Research and Development” (October 22, 2015), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. The LDRD program funds are obtained through a charge to all Laboratory programs. ORNL reports its status to DOE in March of each year.

Senior Laboratory Animal Technician | Center for Cancer Research

Cancer.gov

PROGRAM DESCRIPTION The Laboratory Animal Sciences Program (LASP) provides exceptional quality animal care and technical support services for animal research performed at the National Cancer Institute at the Frederick National Laboratory for Cancer Research. LASP executes this mission by providing a broad spectrum of state-of-the-art technologies and services that are focused on the design, generation, characterization and application of genetically engineered and biological animal models of human disease, which are aimed at the development of targeted diagnostics and therapies. LASP contributes to advancing human health, developing new treatments, and improving existing treatments for cancer and other diseases while ensuring safe and humane treatment of animals. KEY ROLES/RESPONSIBILITIES The Senior Laboratory Animal Technician will be responsible for: Daily tasks associated with the care, breeding and treatment of research animals for experimental purposes Management of rodent breeding colonies consisting of multiple, genetically complex strains and associated record keeping and database management Colony management procedures including: tail clipping, animal identification, weaning Data entry consistent with complex colony management Collection of routine diagnostic samples Coordinating shipment of live animals and specimens Performing rodent experimental procedures including basic necropsy and blood collection Observation and recording of physical signs of animal health Knowledge of safe working practices using chemical carcinogen and biological hazards Work schedule may include weekend and holiday hours This position is in support of the Center for Cancer Research (CCR).

DESALINATION AND WATER TREATMENT RESEARCH AT SANDIA NATIONAL LABORATORIES.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rigali, Mark J.; Miller, James E.; Altman, Susan J.

Water is the backbone of our economy - safe and adequate supplies of water are vital for agriculture, industry, recreation, and human consumption. While our supply of water today is largely safe and adequate, we as a nation face increasing water supply challenges in the form of extended droughts, demand growth due to population increase, more stringent health-based regulation, and competing demands from a variety of users. To meet these challenges in the coming decades, water treatment technologies, including desalination, will contribute substantially to ensuring a safe, sustainable, affordable, and adequate water supply for the United States. This overview documentsmore » Sandia National Laboratories' (SNL, or Sandia) Water Treatment Program which focused on the development and demonstration of advanced water purification technologies as part of the larger Sandia Water Initiative. Projects under the Water Treatment Program include: (1) the development of desalination research roadmaps (2) our efforts to accelerate the commercialization of new desalination and water treatment technologies (known as the 'Jump-Start Program),' (3) long range (high risk, early stage) desalination research (known as the 'Long Range Research Program'), (4) treatment research projects under the Joint Water Reuse & Desalination Task Force, (5) the Arsenic Water Technology Partnership Program, (6) water treatment projects funded under the New Mexico Small Business Administration, (7) water treatment projects for the National Energy Technology Laboratory (NETL) and the National Renewable Energy Laboratory (NREL), (8) Sandia- developed contaminant-selective treatment technologies, and finally (9) current Laboratory Directed Research and Development (LDRD) funded desalination projects.« less

Research challenges and lessons learned from conducting community-based research with the Hmong community.

PubMed

Kue, Jennifer; Thorburn, Sheryl; Keon, Karen Levy

2015-05-01

Conducting research with underserved communities with little exposure to research presents a number of challenges and opportunities. Our study used a community-based approach to better understand factors that influence breast and cervical cancer screening among Hmong women. This article shares lessons learned during the process of developing and conducting qualitative research with a Hmong community with limited experience with research. We conducted 17 key informant and 84 in-depth interviews with Hmong women and men. Research team discussions, insights from Hmong research team members, input from our Community Advisory Committee, and project documents were sources of information about the process of conducting research in this community. Lessons learned concern including a cultural insider as an investigator; building community partnerships and support; establishing and working with a community advisory committee; hiring and training bilingual, bicultural staff; and using culturally appropriate materials and methods in a small, kinship-based community. We used multiple strategies to ensure that this study was conducted in a culturally appropriate manner. The lessons learned from our experiences can provide guidance to researchers on methodological and practical issues in conducting research with the Hmong and can inform future research with the Hmong and other similar underserved populations. © 2014 Society for Public Health Education.

Laboratory directed research and development FY98 annual report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Al-Ayat, R; Holzrichter, J

1999-05-01

In 1984, Congress and the Department of Energy (DOE) established the Laboratory Directed Research and Development (LDRD) Program to enable the director of a national laboratory to foster and expedite innovative research and development (R and D) in mission areas. The Lawrence Livermore National Laboratory (LLNL) continually examines these mission areas through strategic planning and shapes the LDRD Program to meet its long-term vision. The goal of the LDRD Program is to spur development of new scientific and technical capabilities that enable LLNL to respond to the challenges within its evolving mission areas. In addition, the LDRD Program provides LLNLmore » with the flexibility to nurture and enrich essential scientific and technical competencies and enables the Laboratory to attract the most qualified scientists and engineers. The FY98 LDRD portfolio described in this annual report has been carefully structured to continue the tradition of vigorously supporting DOE and LLNL strategic vision and evolving mission areas. The projects selected for LDRD funding undergo stringent review and selection processes, which emphasize strategic relevance and require technical peer reviews of proposals by external and internal experts. These FY98 projects emphasize the Laboratory's national security needs: stewardship of the U.S. nuclear weapons stockpile, responsibility for the counter- and nonproliferation of weapons of mass destruction, development of high-performance computing, and support of DOE environmental research and waste management programs.« less

Open- and closed-formula laboratory animal diets and their importance to research.

PubMed

Barnard, Dennis E; Lewis, Sherry M; Teter, Beverly B; Thigpen, Julius E

2009-11-01

Almost 40 y ago the scientific community was taking actions to control environmental factors that contribute to variation in the responses of laboratory animals to scientific manipulation. Laboratory animal diet was recognized as an important variable. During the 1970s, the American Institute of Nutrition, National Academy of Science, Institute of Laboratory Animal Resources, and Laboratory Animals Centre Diets Advisory Committee supported the use of 'standard reference diets' in biomedical research as a means to improve the ability to replicate research. As a result the AIN76 purified diet was formulated. During this same time, the laboratory animal nutritionist at the NIH was formulating open-formula, natural-ingredient diets to meet the need for standardized laboratory animal diets. Since the development of open-formula diets, fixed-formula and constant-nutrient-concentration closed-formula laboratory animal natural ingredient diets have been introduced to help reduce the potential variation diet can cause in research.

Open- and Closed-Formula Laboratory Animal Diets and Their Importance to Research

PubMed Central

Barnard, Dennis E; Lewis, Sherry M; Teter, Beverly B; Thigpen, Julius E

2009-01-01

Almost 40 y ago the scientific community was taking actions to control environmental factors that contribute to variation in the responses of laboratory animals to scientific manipulation. Laboratory animal diet was recognized as an important variable. During the 1970s, the American Institute of Nutrition, National Academy of Science, Institute of Laboratory Animal Resources, and Laboratory Animals Centre Diets Advisory Committee supported the use of ‘standard reference diets’ in biomedical research as a means to improve the ability to replicate research. As a result the AIN76 purified diet was formulated. During this same time, the laboratory animal nutritionist at the NIH was formulating open-formula, natural-ingredient diets to meet the need for standardized laboratory animal diets. Since the development of open-formula diets, fixed-formula and constant-nutrient–concentration closed-formula laboratory animal natural ingredient diets have been introduced to help reduce the potential variation diet can cause in research. PMID:19930817

M2 .50-cal. Multishot Capabilities at the US Army Research Laboratory

DTIC Science & Technology

2015-09-01

a platform was designed to simulate the 2-round burst of the M2 .50-caliber Browning machine gun (BMG). The 2-round-burst cyclic rate was achieved...ARL-TN-0694 ● SEP 2015 US Army Research Laboratory M2 .50-cal. Multishot Capabilities at the US Army Research Laboratory by...longer needed. Do not return it to the originator. ARL-TN-0694 ● SEP 2015 US Army Research Laboratory M2 .50-cal. Multishot

Research Notes. OERI's Regional Laboratory Technology Efforts.

ERIC Educational Resources Information Center

Garnette, Cheryl P., Ed.; Withrow, Frank B., Ed.

1989-01-01

Examines various educational technology projects that regional laboratories supported by the Office of Educational Research and Improvement (OERI) are undertaking. Highlights include innovative uses of instructional technology; tele-teaching using interactive audio conferencing; making informed decisions about technology; national teleconferences…

Accessibility | Frederick National Laboratory for Cancer Research

Cancer.gov

The Frederick National Laboratory for Cancer Research campus is making every effort to ensure that the information available on our website is accessible to all. If you use special adaptive equipment to access the web and encounter problems when usin

Sandia National Laboratories: Cooperative Research and Development

Science.gov Websites

; Technology Defense Systems & Assessments About Defense Systems & Assessments Program Areas Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

FY2007 Laboratory Directed Research and Development Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Craig, W W; Sketchley, J A; Kotta, P R

The Laboratory Directed Research and Development (LDRD) annual report for fiscal year 2007 (FY07) provides a summary of LDRD-funded projects for the fiscal year and consists of two parts: An introduction to the LDRD Program, the LDRD portfolio-management process, program statistics for the year, and highlights of accomplishments for the year. A summary of each project, submitted by the principal investigator. Project summaries include the scope, motivation, goals, relevance to Department of Energy (DOE)/National Nuclear Security Administration (NNSA) and Lawrence Livermore National Laboratory (LLNL) mission areas, the technical progress achieved in FY07, and a list of publications that resulted frommore » the research in FY07. Summaries are organized in sections by research category (in alphabetical order). Within each research category, the projects are listed in order of their LDRD project category: Strategic Initiative (SI), Exploratory Research (ER), Laboratory-Wide Competition (LW), and Feasibility Study (FS). Within each project category, the individual project summaries appear in order of their project tracking code, a unique identifier that consists of three elements. The first is the fiscal year the project began, the second represents the project category, and the third identifies the serial number of the proposal for that fiscal year.« less

Laboratory directed research and development fy1999 annual report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Al-Ayat, R A

2000-04-11

The Lawrence Livermore National Laboratory (LLNL) was founded in 1952 and has been managed since its inception by the University of California (UC) for the U.S. Department of Energy (DOE). Because of this long association with UC, the Laboratory has been able to recruit a world-class workforce, establish an atmosphere of intellectual freedom and innovation, and achieve recognition in relevant fields of knowledge as a scientific and technological leader. This environment and reputation are essential for sustained scientific and technical excellence. As a DOE national laboratory with about 7,000 employees, LLNL has an essential and compelling primary mission to ensuremore » that the nation's nuclear weapons remain safe, secure, and reliable and to prevent the spread and use of nuclear weapons worldwide. The Laboratory receives funding from the DOE Assistant Secretary for Defense Programs, whose focus is stewardship of our nuclear weapons stockpile. Funding is also provided by the Deputy Administrator for Defense Nuclear Nonproliferation, many Department of Defense sponsors, other federal agencies, and the private sector. As a multidisciplinary laboratory, LLNL has applied its considerable skills in high-performance computing, advanced engineering, and the management of large research and development projects to become the science and technology leader in those areas of its mission responsibility. The Laboratory Directed Research and Development (LDRD) Program was authorized by the U.S. Congress in 1984. The Program allows the Director of each DOE laboratory to fund advanced, creative, and innovative research and development (R&D) activities that will ensure scientific and technical vitality in the continually evolving mission areas at DOE and the Laboratory. In addition, the LDRD Program provides LLNL with the flexibility to nurture and enrich essential scientific and technical competencies, which attract the most qualified scientists and engineers. The LDRD

Model of the NACA's Aircraft Engine Research Laboratory during its Construction

NASA Image and Video Library

1942-08-21

Zella Morewitz poses with a model of the National Advisory Committee for Aeronautics (NACA) Aircraft Engine Research Laboratory, currently the NASA Glenn Research Center. The model was displayed in the Administration Building during the construction of the laboratory in the early 1940s. Detailed models of the individual test facilities were also fabricated and displayed in the facilities. The laboratory was built on a wedge of land between the Cleveland Municipal Airport on the far side and the deep curving valley etched by the Rocky River on the near end. Roughly only a third of the laboratory's semicircle footprint was initially utilized. Additional facilities were added to the remaining areas in the years after World War II. In the late 1950s the site was supplemented by the acquisition of additional adjacent land. Morewitz joined the NACA in 1935 as a secretary in the main office at the Langley Memorial Aeronautical Laboratory. In September 1940 she took on the task of setting up and guiding an office dedicated to the design of the NACA’s new engine research laboratory. Morewitz and the others in the design office transferred to Cleveland in December 1941 to expedite the construction. Morewitz served as Manager Ray Sharp’s secretary for six years and was a popular figure at the new laboratory. In December 1947 Morewitz announced her engagement to Langley researcher Sidney Batterson and moved back to Virginia.

A 50-year research journey. From laboratory to clinic.

PubMed

Ross, John

2009-01-01

Prior important research is not always cited, exemplified by Oswald Avery's pioneering discovery that DNA is the genetic transforming factor; it was not cited by Watson and Crick 10 years later. My first laboratory research (National Institutes of Health 1950s) resulted in the clinical development of transseptal left heart catheterization. Laboratory studies on cardiac muscle mechanics in normal and failing hearts led to the concept of afterload mismatch with limited preload reserve. At the University of California, San Diego in La Jolla (1968) laboratory experiments on coronary artery reperfusion after sustained coronary occlusion showed salvage of myocardial tissue, a potential treatment for acute myocardial infarction proven in clinical trials of thrombolysis 14 years later. Among 60 trainees who worked with me in La Jolla, one-third were Japanese and some of their important laboratory experiments are briefly recounted, beginning with Sasayama, Tomoike and Shirato in the 1970 s. Recently, we developed a method for cardiac gene transfer, and subsequently we showed that gene therapy for the defect in cardiomyopathic hamsters halted the progression of advanced disease. Cardiovascular research and medicine are producing continuing advances in technologies for gene transfer and embryonic stem cell transplantation, targeting of small molecules, and tissue and organ engineering.

Considerations for Conducting Plant Research in Open Atmosphere Chambers on ISS

NASA Astrophysics Data System (ADS)

Wheeler, Raymond; Hummerick, Mary; Graham, Thomas; Dixit, Anirudha; Massa, Gioia

The access to spaceflight and now the International Space Station has provided plant researchers a laboratory that is in continuous freefall (near weightlessness). As veteran spaceflight investigators know too well, research in space is difficult to conduct and the experiments are often confounded by secondary events. An example of this is the distribution of water and gases in rooting systems in µ-gravity. Since the water does not settle to the ”bottom” of the rooting media in space, there can be poor distribution and movement of water and oxygen, which in turn can stress the plants. This also creates challenges for conducting ground controls where the logical approach is to use the same volume of water as in space. But under 1-g, the water does settle to the bottom of the root zone, which leaves less in the upper profile of the rooting medium. In addition, some chambers such as the Russian Svet (on Mir), Lada (ISS), and NASA’s Veggie chamber were or are open to the cabin air. This simplifies the hardware development and allows the use of cabin air for cooling and supplying CO2 to the plants. Yet it also exposes the plants to the cabin air, which could have very high CO2 levels (e.g., 3000 to 6000 ppm), low humidity, and trace contaminants that might be below the limits for human concerns but could still affect plants. A known effect of these “super-elevated” CO2 levels on many dicot species is increased transpiration due to elevated stomatal conductance, both during the light and the dark cycles. Examples of these secondary effects will be discussed, along with potential approaches for conducting adequate ground controls.

Air conditioning a vaccine laboratory. [Connaught Medical Research Laboratory, Toronto, Canada

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ross J.

1976-05-01

In 1974, the new Bacterial Vaccine Building of Connaught Medical Research Laboratories, Toronto, Canada, was opened to produce such vaccines as pertussis, typhoid, paratyphoids, and cholera and such toxoids as staphylococcus, diphtheria, and tetanus. It also produces other medicinal products. The layout of the complex and the air conditioning system necessary in all zones are described and schematically shown. (MCW)

Research Opportunities at Storm Peak Laboratory

NASA Astrophysics Data System (ADS)

Hallar, A. G.; McCubbin, I. B.

2006-12-01

The Desert Research Institute (DRI) operates a high elevation facility, Storm Peak Laboratory (SPL), located on the west summit of Mt. Werner in the Park Range near Steamboat Springs, Colorado at an elevation of 3210 m MSL (Borys and Wetzel, 1997). SPL provides an ideal location for long-term research on the interactions of atmospheric aerosol and gas- phase chemistry with cloud and natural radiation environments. The ridge-top location produces almost daily transition from free tropospheric to boundary layer air which occurs near midday in both summer and winter seasons. Long-term observations at SPL document the role of orographically induced mixing and convection on vertical pollutant transport and dispersion. During winter, SPL is above cloud base 25% of the time, providing a unique capability for studying aerosol-cloud interactions (Borys and Wetzel, 1997). A comprehensive set of continuous aerosol measurements was initiated at SPL in 2002. SPL includes an office-type laboratory room for computer and instrumentation setup with outside air ports and cable access to the roof deck, a cold room for precipitation and cloud rime ice sample handling and ice crystal microphotography, a 150 m2 roof deck area for outside sampling equipment, a full kitchen and two bunk rooms with sleeping space for nine persons. The laboratory is currently well equipped for aerosol and cloud measurements. Particles are sampled from an insulated, 15 cm diameter manifold within approximately 1 m of its horizontal entry point through an outside wall. The 4 m high vertical section outside the building is capped with an inverted can to exclude large particles.

Bioethical Issues in Conducting Pediatric Dentistry Clinical Research.

PubMed

Garrocho-Rangel, Arturo; Cerda-Cristerna, Bernardino; Pozos-Guillen, Amaury

Pediatric clinical research on new drugs and biomaterials involves children in order to create valid and generalizable knowledge. Research on vulnerable populations, such as children, is necessary but only admissible when researchers strictly follow methodological and ethical standards, together with the respect to human rights; and very especially when the investigation cannot be conducted with other population or when the potential benefits are specifically for that age group. Clinical research in Pediatric Dentistry is not an exception. The aim of the present article was to provide the bioethical principles (with respect to the child/parents' autonomy, benefit/risk analysis, and distributive justice), and recommendations, including informed consent, research ethics committees, conflict of interest, and the "equipoise" concept. Current and future worldwide oral health research in children and adolescents must be conducted incorporating their perspectives in the decision-making process as completely as possible. This concept must be carefully considered when a dental clinical study research is going to be planned and conducted, especially in the case of randomized controlled trials, in which children will be recruited as participants.

A laboratory medicine residency training program that includes clinical consultation and research.

PubMed

Spitzer, E D; Pierce, G F; McDonald, J M

1990-04-01

We describe a laboratory medicine residency training program that includes ongoing interaction with both clinical laboratories and clinical services as well as significant research experience. Laboratory medicine residents serve as on-call consultants in the interpretation of test results, design of testing strategies, and assurance of test quality. The consultative on-call beeper system was evaluated and is presented as an effective method of clinical pathology training that is well accepted by the clinical staff. The research component of the residency program is also described. Together, these components provide training in real-time clinical problem solving and prepare residents for the changing technological environment of the clinical laboratory. At the completion of the residency, the majority of the residents are qualified laboratory subspecialists and are also capable of running an independent research program.

Handbook of acute toxicity of chemicals to fish and aquatic invertebrates : summaries of toxicity tests conducted at Columbia National Fisheries Research Laboratory, 1965-78

USGS Publications Warehouse

Johnson, W. Waynon; Finley, Mack T.

1980-01-01

Acute toxicity is a major subject of research at Columbia National Fisheries Research Laboratory for evaluating the impact of toxic chemicals on fishery resources. The Laboratory has played a leading role in developing research technology for toxicity testing and data interpretation. In 1965-78, more than 400 chemicals were tested against a variety of invertebrates and fish species representative of both cold- and warm-water climates.The use of acute toxicity tests for assessing the potential hazard of chemical contaminants to aquatic organisms is well documented (Boyd 1957; Henderson et al. 1960; Sanders and Cope 1966; Macek and McAllister 1970). Static acute toxicity tests provide rapid and (within limits) reproducible concentration-response curves for estimating toxic effects of chemicals on aquatic organisms. These tests provide a database for determining relative toxicity of a large number of chemicals to a variety of species and for estimating acute effects of chemical spills on natural aquatic systems; they also assist in determining priority and design of additional toxicity studies.Acute toxicity tests usually provide estimates of the exposure concentration causing 50% mortality (LC50) to test organisms during a specified period of time. For certain invertebrates, the effective concentration is based on immobilization, or some other identifiable endpoint, rather than on lethality. The application of the LC50 has gained acceptance among toxicologists and is generally the most highly rated test for assessing potential adverse effects of chemical contaminants to aquatic life (Brungs and Mount 1978; American Institute for Biological Sciences 1978a).The literature contains numerous papers dealing with the acute toxicity of chemicals to freshwater organisms. However, there is a tremendous need for a concise compendium of toxicity data covering a large variety of chemicals and test species. This Handbook is a compilation of a large volume of acute toxicity data

Firefighter exercise protocols conducted in an environmental chamber: developing a laboratory-based simulated firefighting protocol.

PubMed

Ensari, Ipek; Motl, Robert W; Klaren, Rachel E; Fernhall, Bo; Smith, Denise L; Horn, Gavin P

2017-05-01

A standard exercise protocol that allows comparisons across various ergonomic studies would be of great value for researchers investigating the physical and physiological strains of firefighting and possible interventions for reducing the demands. We compared the pattern of cardiorespiratory changes from 21 firefighters during simulated firefighting activities using a newly developed firefighting activity station (FAS) and treadmill walking both performed within an identical laboratory setting. Data on cardiorespiratory parameters and core temperature were collected continuously using a portable metabolic unit and a wireless ingestible temperature probe. Repeated measures ANOVA indicated distinct patterns of change in cardiorespiratory parameters and heart rate between conditions. The pattern consisted of alternating periods of peaks and nadirs in the FAS that were qualitatively and quantitatively similar to live fire activities, whereas the same parameters increased logarithmically in the treadmill condition. Core temperature increased in a similarly for both conditions, although more rapidly in the FAS. Practitioner Summary: The firefighting activity station (FAS) yields a pattern of cardiorespiratory responses qualitatively and quantitatively similar to live fire activities, significantly different than treadmill walking. The FAS can be performed in a laboratory/clinic, providing a potentially standardised protocol for testing interventions to improve health and safety and conducting return to duty decisions.

Idaho National Laboratory Directed Research and Development FY-2009

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2010-03-01

The FY 2009 Laboratory Directed Research and Development (LDRD) Annual Report is a compendium of the diverse research performed to develop and ensure the INL's technical capabilities can support the future DOE missions and national research priorities. LDRD is essential to the INL - it provides a means for the laboratory to pursue novel scientific and engineering research in areas that are deemed too basic or risky for programmatic investments. This research enhances technical capabilities at the laboratory, providing scientific and engineering staff with opportunities for skill building and partnership development. Established by Congress in 1991, LDRD proves its benefitmore » each year through new programs, intellectual property, patents, copyrights, publications, national and international awards, and new hires from the universities and industry, which helps refresh the scientific and engineering workforce. The benefits of INL's LDRD research are many as shown in the tables below. Last year, 91 faculty members from various universities contributed to LDRD research, along with 7 post docs and 64 students. Of the total invention disclosures submitted in FY 2009, 7 are attributable to LDRD research. Sixty three refereed journal articles were accepted or published, and 93 invited presentations were attributable to LDRD research conducted in FY 2009. The LDRD Program is administered in accordance with requirements set in DOE Order 413.2B, accompanying contractor requirements, and other DOE and federal requirements invoked through the INL contract. The LDRD Program is implemented in accordance with the annual INL LDRD Program Plan, which is approved by the DOE, Nuclear Energy Program Secretarial Office. This plan outlines the method the laboratory uses to develop its research portfolio, including peer and management reviews, and the use of other INL management systems to ensure quality, financial, safety, security and environmental requirements and risks are

Conducting qualitative research in audiology: a tutorial.

PubMed

Knudsen, Line V; Laplante-Lévesque, Ariane; Jones, Lesley; Preminger, Jill E; Nielsen, Claus; Lunner, Thomas; Hickson, Louise; Naylor, Graham; Kramer, Sophia E

2012-02-01

Qualitative research methodologies are being used more frequently in audiology as it allows for a better understanding of the perspectives of people with hearing impairment. This article describes why and how international interdisciplinary qualitative research can be conducted. This paper is based on a literature review and our recent experience with the conduction of an international interdisciplinary qualitative study in audiology. We describe some available qualitative methods for sampling, data collection, and analysis and we discuss the rationale for choosing particular methods. The focus is on four approaches which have all previously been applied to audiologic research: grounded theory, interpretative phenomenological analysis, conversational analysis, and qualitative content analysis. This article provides a review of methodological issues useful for those designing qualitative research projects in audiology or needing assistance in the interpretation of qualitative literature.

Regional Educational Laboratory Researcher-Practitioner Partnerships: Documenting the Research Alliance Experience. REL 2018-291

ERIC Educational Resources Information Center

Scher, Lauren; McCowan, Ronald; Castaldo-Walsh, Cynthia

2018-01-01

This report provides a detailed account of the Regional Educational Laboratory (REL) Program's experience establishing and supporting research-practice partnerships (called "research alliances") during its 2012-17 contract cycle. The report adds to the growing literature base on researcher-practitioner partnerships by sharing how the…

The taming of the prairie: A century of agricultural research at the Northern Great Plains Research Laboratory

USDA-ARS?s Scientific Manuscript database

Nearly a century after Congress authorized the Northern Great Plains Research Laboratory, it had approximately 35 employees and an annual budget of 3.4 million dollars. The long history of research accomplishments from the Laboratory have been well accepted by the agricultural community and have ide...

Groundbreaking for the NACA’s Aircraft Engine Research Laboratory

NASA Image and Video Library

1941-01-21

Local politicians and National Advisory Committee for Aeronautics (NACA) officials were on hand for the January 23, 1941 groundbreaking for the NACA’s Aircraft Engine Research Laboratory (AERL). The NACA was established in 1915 to coordinate the nation’s aeronautical research. The committee opened a research laboratory at Langley Field in 1920. By the late 1930s, however, European nations, Germany in particular, were building faster and higher flying aircraft. The NACA decided to expand with a new Ames Aeronautical Laboratory dedicated to high-speed flight and the AERL to handle engine-related research. The NACA examined a number of Midwest locations for its new engine lab before deciding on Cleveland. At the time, Cleveland possessed the nation’s most advanced airport, several key aircraft manufacturing companies, and was home to the National Air Races. Local officials were also able to broker a deal with the power company to discount its electricity rates if the large wind tunnels were operated overnight. The decision was made in October 1940, and the groundbreaking alongside the airport took place on January 23, 1941. From left to right: William Hopkins, John Berry, Ray Sharp, Frederick Crawford, George Brett, Edward Warner, Sydney Kraus, Edward Blythin, and George Lewis

Laboratory Directed Research and Development Program FY 2006

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hansen

2007-03-08

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operatemore » unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness.« less

Laboratory Directed Research and Development Program Assessment for FY 2016

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hatton, Diane; Flynn, Liz

2017-03-31

Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy in accordance with DOE Order 413.2C, and this report fulfills that requirement.

Laboratory Directed Research and Development Program Assessment for FY 2017

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderson, Jack; Flynn, Liz

Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy in accordance with DOE Order 413.2C. This report fulfills that requirement.

Collaboration Agreement | Frederick National Laboratory for Cancer Research

Cancer.gov

A Collaboration Agreement is appropriate for research collaboration involving intellectual and material contributions by the Frederick National Laboratory and external partner(s). It is useful for proof-of-concept studies. Includes brief re

Guidelines for Biosafety Training Programs for Workers Assigned to BSL-3 Research Laboratories.

PubMed

Homer, Lesley C; Alderman, T Scott; Blair, Heather Ann; Brocard, Anne-Sophie; Broussard, Elaine E; Ellis, Robert P; Frerotte, Jay; Low, Eleanor W; McCarthy, Travis R; McCormick, Jessica M; Newton, JeT'Aime M; Rogers, Francine C; Schlimgen, Ryan; Stabenow, Jennifer M; Stedman, Diann; Warfield, Cheryl; Ntiforo, Corrie A; Whetstone, Carol T; Zimmerman, Domenica; Barkley, Emmett

2013-03-01

The Guidelines for Biosafety Training Programs for Workers Assigned to BSL-3 Research Laboratories were developed by biosafety professionals who oversee training programs for the 2 national biocontainment laboratories (NBLs) and the 13 regional biocontainment laboratories (RBLs) that participate in the National Institute of Allergy and Infectious Diseases (NIAID) NBL/RBL Network. These guidelines provide a general training framework for biosafety level 3 (BSL-3) high-containment laboratories, identify key training concepts, and outline training methodologies designed to standardize base knowledge, understanding, and technical competence of laboratory personnel working in high-containment laboratories. Emphasis is placed on building a culture of risk assessment-based safety through competency training designed to enhance understanding and recognition of potential biological hazards as well as methods for controlling these hazards. These guidelines may be of value to other institutions and academic research laboratories that are developing biosafety training programs for BSL-3 research.

Naval Research Laboratory Major Facilities 2008

DTIC Science & Technology

2008-10-01

Development Laboratory • Secure Supercomputing Facility • CBD/Tilghman Island IR Field Evaluation Facility • Ultra-Short-Pulse Laser Effects Research...EMI Test Facility • Proximity Operations Testbed GENERAL INFORMATION • Maps EX EC U TI V E D IR EC TO RA TE Code 1100 – Institute for Nanoscience...facility: atomic force microscope (AFM); benchtop transmission electron microscope (TEM); cascade probe station; critical point dryer ; dual beam focused

Research and Laboratory Instruction--An Experiment in Teaching

ERIC Educational Resources Information Center

Kramm, Kenneth R.

1976-01-01

Describes an attempt to incorporate research into laboratory work in an introductory ecology class and a senior seminar. The investigation involves the examination of rhythms of food consumption and circadian activities in humans. (GS)

Contact Us | Frederick National Laboratory for Cancer Research

Cancer.gov

E-mail:fnlwebsite@nih.gov Phone:(301) 846-1000 Postal Mail: Frederick National Laboratory for Cancer Research P.O. Box B Frederick, MD 21702-1201 Human Resources Office of Recruitment (301) 846-5362 Jim

Global Impact | Frederick National Laboratory for Cancer Research

Cancer.gov

Through its direct support of clinical research, Frederick National Laboratory activities are not limited to national programs. The labis actively involved in more than 400 domestic and international studies related to cancer; influenza, HIV, E

Locations Accessible | Frederick National Laboratory for Cancer Research

Cancer.gov

The Frederick National Laboratory for Cancer Research campus is located 50 miles northwest of Washington, D.C., and 50 miles west of Baltimore, Maryland, in Frederick, Maryland.Operations and Technical Support contractor Leidos Biomedical Resea

Steam Plant at the Aircraft Engine Research Laboratory

NASA Image and Video Library

1945-09-21

The Steam Plant at the National Advisory Committee for Aeronautics (NACA) Aircraft Engine Research Laboratory supplies steam to the major test facilities and office buildings. Steam is used for the Icing Research Tunnel's spray system and the Engine Research Building’s desiccant air dryers. In addition, its five boilers supply heat to various buildings and the cafeteria. Schirmer-Schneider Company built the $141,000 facility in the fall of 1942, and it has been in operation ever since.

Mapping Maize Genes: A Series of Research-Based Laboratory Exercises

ERIC Educational Resources Information Center

Makarevitch, Irina; Kralich, Elizabeth

2011-01-01

Open-ended, inquiry-based multiweek laboratory exercises are the key elements to increasing students' understanding and retention of the major biological concepts. Including original research into undergraduate teaching laboratories has also been shown to motivate students and improve their learning. Here, we present a series of original…

The Laboratory for Terrestrial Physics

NASA Technical Reports Server (NTRS)

2003-01-01

The Laboratory for Terrestrial Physics is dedicated to the advancement of knowledge in Earth and planetary science, by conducting innovative research using space technology. The Laboratory's mission and activities support the work and new initiatives at NASA's Goddard Space Flight Center (GSFC). The Laboratory's success contributes to the Earth Science Directorate as a national resource for studies of Earth from Space. The Laboratory is part of the Earth Science Directorate based at the GSFC in Greenbelt, MD. The Directorate itself is comprised of the Global Change Data Center (GCDC), the Space Data and Computing Division (SDCD), and four science Laboratories, including Laboratory for Terrestrial Physics, Laboratory for Atmospheres, and Laboratory for Hydrospheric Processes all in Greenbelt, MD. The fourth research organization, Goddard Institute for Space Studies (GISS), is in New York, NY. Relevant to NASA's Strategic Plan, the Laboratory ensures that all work undertaken and completed is within the vision of GSFC. The philosophy of the Laboratory is to balance the completion of near term goals, while building on the Laboratory's achievements as a foundation for the scientific challenges in the future.

Michigan/Air Force Research Laboratory (AFRL) Collaborative Center in Control Science (MACCCS)

DTIC Science & Technology

2016-09-01

AFRL-RQ-WP-TR-2016-0139 MICHIGAN/AIR FORCE RESEARCH LABORATORY (AFRL) COLLABORATIVE CENTER IN CONTROL SCIENCE (MACCCS) Anouck Girard...Final 18 April 2007 – 30 September 2016 4. TITLE AND SUBTITLE MICHIGAN/AIR FORCE RESEARCH LABORATORY (AFRL) COLLABORATIVE CENTER IN CONTROL SCIENCE...and amplify an internationally recognized center of excellence in control science research and education, through interaction between the faculty and

Smart Electronic Laboratory Notebooks for the NIST Research Environment.

PubMed

Gates, Richard S; McLean, Mark J; Osborn, William A

2015-01-01

Laboratory notebooks have been a staple of scientific research for centuries for organizing and documenting ideas and experiments. Modern laboratories are increasingly reliant on electronic data collection and analysis, so it seems inevitable that the digital revolution should come to the ordinary laboratory notebook. The most important aspect of this transition is to make the shift as comfortable and intuitive as possible, so that the creative process that is the hallmark of scientific investigation and engineering achievement is maintained, and ideally enhanced. The smart electronic laboratory notebooks described in this paper represent a paradigm shift from the old pen and paper style notebooks and provide a host of powerful operational and documentation capabilities in an intuitive format that is available anywhere at any time.

Smart Electronic Laboratory Notebooks for the NIST Research Environment

PubMed Central

Gates, Richard S.; McLean, Mark J.; Osborn, William A.

2015-01-01

Laboratory notebooks have been a staple of scientific research for centuries for organizing and documenting ideas and experiments. Modern laboratories are increasingly reliant on electronic data collection and analysis, so it seems inevitable that the digital revolution should come to the ordinary laboratory notebook. The most important aspect of this transition is to make the shift as comfortable and intuitive as possible, so that the creative process that is the hallmark of scientific investigation and engineering achievement is maintained, and ideally enhanced. The smart electronic laboratory notebooks described in this paper represent a paradigm shift from the old pen and paper style notebooks and provide a host of powerful operational and documentation capabilities in an intuitive format that is available anywhere at any time. PMID:26958447

André Cournand, Bellevue's Cardiopulmonary Laboratory, and Research on Heart Failure.

PubMed

Braunwald, Eugene

2018-02-01

In 1954-1955, the author served as a research fellow in the cardiopulmonary laboratory led by André Cournand at Bellevue Hospital in New York. Cournand was a pulmonary physiologist and a professor of medicine at Columbia University. In his quest to obtain mixed venous blood to calculate pulmonary blood flow, he catheterized the right atrium, right ventricle, and pulmonary artery in patients and also measured the pressures in these chambers. Cournand and his collaborators soon appreciated the enormous potential of cardiac catheterization in deepening the understanding of cardiovascular pathophysiology. After a series of groundbreaking studies, Cournand and his coworker Dickinson Richards, as well as German physician Werner Forssmann, were awarded a Nobel Prize in 1956. Cournand's laboratory, his work habits, and his rigorous approach to science are described, as well as the stimulation the author received during the author's fellowship. As a result, the author went on to extend to the left side of the heart the observations that the Cournand group had conducted in the right heart. Also, the author continued Cournand's work on heart failure by developing techniques to measure ventricular function in patients and to describe the neurohumoral changes that occur in human heart failure.

Conducting transcultural research: critical thinking in Thailand.

PubMed

Jenkins, Sheryl D

2011-01-01

Little has been written to help researchers prepare for the unique challenges of conducting transcultural research. The purpose of this article is to discuss issues that arose during the planning and execution of a transcultural study designed to compare critical thinking in Thailand and the United States. The challenges of identifying a research site, selecting participants, incorporating Thai research into the literature review, traveling and living in a foreign culture, overcoming cultural barriers to research, and strengthening internal validity and reliability are addressed.

Frontiers: Research highlights 1946-1996 [50th Anniversary Edition. Argonne National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-12-31

This special edition of 'Frontiers' commemorates Argonne National Laboratory's 50th anniversary of service to science and society. America's first national laboratory, Argonne has been in the forefront of U.S. scientific and technological research from its beginning. Past accomplishments, current research, and future plans are highlighted.

Frontiers: Research Highlights 1946-1996 [50th Anniversary Edition. Argonne National Laboratory

DOE R&D Accomplishments Database

1996-01-01

This special edition of 'Frontiers' commemorates Argonne National Laboratory's 50th anniversary of service to science and society. America's first national laboratory, Argonne has been in the forefront of U.S. scientific and technological research from its beginning. Past accomplishments, current research, and future plans are highlighted.

Material Transfer Agreement (MTA) | Frederick National Laboratory for Cancer Research

Cancer.gov

Material Transfer Agreements are appropriate for exchange of materials into or out of the Frederick National Laboratory for research or testing purposes, with no collaborative research by parties involving the materials.

76 FR 1212 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-07

... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board Panel for Eligibility; Notice of Meeting The Department of Veterans Affairs (VA) gives notice under the Public Law 92-463 (Federal Advisory...

75 FR 57833 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-22

... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board; Notice of Meetings The Department of Veterans Affairs gives notice under the Public Law 92-463 (Federal Advisory Committee Act) that...

76 FR 66367 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-26

... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board; Notice of Meetings The Department of Veterans Affairs gives notice under the Public Law 92-463 (Federal Advisory Committee Act) that...

77 FR 26069 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-02

... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board, Notice of Meeting Amendment The Department of Veterans Affairs (VA) gives notice under the Public Law 92-463 (Federal Advisory Committee Act...

76 FR 79273 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-21

... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board Panel for Eligibility, Notice of Meeting The Department of Veterans Affairs (VA) gives notice under Public Law 92-463 (Federal Advisory...

New Laboratory Technique to Determine Thermal Conductivity of Complex Regolith Simulants Under High Vacuum

NASA Astrophysics Data System (ADS)

Ryan, A. J.; Christensen, P. R.

2016-12-01

Laboratory measurements have been necessary to interpret thermal data of planetary surfaces for decades. We present a novel radiometric laboratory method to determine temperature-dependent thermal conductivity of complex regolith simulants under high vacuum and across a wide range of temperatures. Here, we present our laboratory method, strategy, and initial results. This method relies on radiometric temperature measurements instead of contact measurements, eliminating the need to disturb the sample with thermal probes. We intend to determine the conductivity of grains that are up to 2 cm in diameter and to parameterize the effects of angularity, sorting, layering, composition, and cementation. These results will support the efforts of the OSIRIS-REx team in selecting a site on asteroid Bennu that is safe and meets grain size requirements for sampling. Our system consists of a cryostat vacuum chamber with an internal liquid nitrogen dewar. A granular sample is contained in a cylindrical cup that is 4 cm in diameter and 1 to 6 cm deep. The surface of the sample is exposed to vacuum and is surrounded by a black liquid nitrogen cold shroud. Once the system has equilibrated at 80 K, the base of the sample cup is rapidly heated to 450 K. An infrared camera observes the sample from above to monitor its temperature change over time. We have built a time-dependent finite element model of the experiment in COMSOL Multiphysics. Boundary temperature conditions and all known material properties (including surface emissivities) are included to replicate the experiment as closely as possible. The Optimization module in COMSOL is specifically designed for parameter estimation. Sample thermal conductivity is assumed to be a quadratic or cubic polynomial function of temperature. We thus use gradient-based optimization methods in COMSOL to vary the polynomial coefficients in an effort to reduce the least squares error between the measured and modeled sample surface temperature.

Summer Research Experiences with a Laboratory Tokamak

NASA Astrophysics Data System (ADS)

Farley, N.; Mauel, M.; Navratil, G.; Cates, C.; Maurer, D.; Mukherjee, S.; Shilov, M.; Taylor, E.

1998-11-01

Columbia University's Summer Research Program for Secondary School Science Teachers seeks to improve middle and high school student understanding of science. The Program enhances science teachers' understanding of the practice of science by having them participate for two consecutive summers as members of laboratory research teams led by Columbia University faculty. In this poster, we report the research and educational activities of two summer internships with the HBT-EP research tokamak. Research activities have included (1) computer data acquisition and the representation of complex plasma wave phenomena as audible sounds, and (2) the design and construction of pulsed microwave systems to experience the design and testing of special-purpose equipment in order to achieve a specific technical goal. We also present an overview of the positive impact this type of plasma research involvement has had on high school science teaching.

Pacific Northwest Laboratory annual report for 1989 to the DOE Office of Energy Research - Part 1: Biomedical Sciences

DOE Office of Scientific and Technical Information (OSTI.GOV)

Park, J.F.

This report summarizes progress on OHER human health, biological, general life sciences, and medical applications research programs conducted at PNL in FY 1989. The research develops the knowledge and scientific principles necessary to identify, understand, and anticipate the long-term health consequences of energy-related radiation and chemicals. Our continuing emphasis is to decrease the uncertainty of health risk estimates from existing and developing energy-related technologies through an increased understanding of how radiation and chemicals cause biological damage. The sequence of this report of PNL research reflects the OHER programmatic structure. The first section, on human health research, concerns statistical and epidemiologicalmore » studies for assessing health risks. The next section contains reports of biological research in laboratory animals and in vitro cell systems, including research with radionuclides and chemicals. The general life sciences research section reports research conducted for the OHER human genome research program, and the medical applications section summarizes commercial radioisotope production and distribution activities at DOE facilities. 6 refs., 50 figs., 35 tabs.« less

Argonne National Laboratory Annual Report of Laboratory Directed Research and Development program activities FY 2011.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Office of The Director)

As a national laboratory Argonne concentrates on scientific and technological challenges that can only be addressed through a sustained, interdisciplinary focus at a national scale. Argonne's eight major initiatives, as enumerated in its strategic plan, are Hard X-ray Sciences, Leadership Computing, Materials and Molecular Design and Discovery, Energy Storage, Alternative Energy and Efficiency, Nuclear Energy, Biological and Environmental Systems, and National Security. The purposes of Argonne's Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel technical concepts, enhance the Laboratory's research and development (R and D) capabilities, and pursue its strategic goals. projects are selectedmore » from proposals for creative and innovative R and D studies that require advance exploration before they are considered to be sufficiently developed to obtain support through normal programmatic channels. Among the aims of the projects supported by the LDRD Program are the following: establishment of engineering proof of principle, assessment of design feasibility for prospective facilities, development of instrumentation or computational methods or systems, and discoveries in fundamental science and exploratory development.« less

FY04 Engineering Technology Reports Laboratory Directed Research and Development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sharpe, R M

2005-01-27

This report summarizes the science and technology research and development efforts in Lawrence Livermore National Laboratory's Engineering Directorate for FY2004, and exemplifies Engineering's more than 50-year history of developing the technologies needed to support the Laboratory's missions. Engineering has been a partner in every major program and project at the Laboratory throughout its existence and has prepared for this role with a skilled workforce and the technical resources developed through venues like the Laboratory Directed Research and Development Program (LDRD). This accomplishment is well summarized by Engineering's mission: ''Enable program success today and ensure the Laboratory's vitality tomorrow''. Engineering's investmentmore » in technologies is carried out through two programs, the ''Tech Base'' program and the LDRD program. LDRD is the vehicle for creating those technologies and competencies that are cutting edge. These require a significant level of research or contain some unknown that needs to be fully understood. Tech Base is used to apply technologies to a Laboratory need. The term commonly used for Tech Base projects is ''reduction to practice''. Therefore, the LDRD report covered here has a strong research emphasis. Areas that are presented all fall into those needed to accomplish our mission. For FY2004, Engineering's LDRD projects were focused on mesoscale target fabrication and characterization, development of engineering computational capability, material studies and modeling, remote sensing and communications, and microtechnology and nanotechnology for national security applications. Engineering's five Centers, in partnership with the Division Leaders and Department Heads, are responsible for guiding the long-term science and technology investments for the Directorate. The Centers represent technologies that have been identified as critical for the present and future work of the Laboratory, and are chartered to develop their

Optical laboratory facilities at the Finnish Meteorological Institute - Arctic Research Centre

NASA Astrophysics Data System (ADS)

Lakkala, Kaisa; Suokanerva, Hanne; Matti Karhu, Juha; Aarva, Antti; Poikonen, Antti; Karppinen, Tomi; Ahponen, Markku; Hannula, Henna-Reetta; Kontu, Anna; Kyrö, Esko

2016-07-01

This paper describes the laboratory facilities at the Finnish Meteorological Institute - Arctic Research Centre (FMI-ARC, http://fmiarc.fmi.fi). They comprise an optical laboratory, a facility for biological studies, and an office. A dark room has been built, in which an optical table and a fixed lamp test system are set up, and the electronics allow high-precision adjustment of the current. The Brewer spectroradiometer, NILU-UV multifilter radiometer, and Analytical Spectral Devices (ASD) spectroradiometer of the FMI-ARC are regularly calibrated or checked for stability in the laboratory. The facilities are ideal for responding to the needs of international multidisciplinary research, giving the possibility to calibrate and characterize the research instruments as well as handle and store samples.

New working paradigms in research laboratories.

PubMed

Keighley, Wilma; Sewing, Andreas

2009-07-01

Work in research laboratories, especially within centralised functions in larger organisations, is changing fast. With easier access to external providers and Contract Research Organisations, and a focus on budgets and benchmarking, scientific expertise has to be complemented with operational excellence. New concepts, globally shared projects and restricted resources highlight the constraints of traditional operating models working from Monday to Friday and nine to five. Whilst many of our scientists welcome this new challenge, organisations have to enable and foster a more business-like mindset. Organisational structures, remuneration, as well as systems in finance need to be adapted to build operations that are best-in-class rather than merely minimising negative impacts of current organisational structures.

Research and Teaching: The Impact of a Four-Step Laboratory Pedagogical Framework on Biology Students' Perceptions of Laboratory Skills, Knowledge, and Interest in Research

ERIC Educational Resources Information Center

McLaughlin, Jacqueline Shea; Favre, David E.; Weinstein, Suzanne E.; Goedhart, Christine M.

2017-01-01

Authentic undergraduate research laboratory experiences are essential to aid in the implementation of science education reform mandates and to effectively train a new generation of biology students. Here we present assessment data on a unique four-step laboratory pedagogical framework that allows students to develop scientific thinking and…

Savannah River Ecology Laboratory Annual Technical Progress Report of Ecological Research, June 30, 2001

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bertsch, Paul M.; Janecek, Laura; Rosier, Brenda

2001-06-30

The Savannah River Ecology Laboratory (SREL) is a research unit of the University of Georgia (UGA) and has been conducting ecological research on the Savannah River Site (SRS) in South Carolina for 50 years. The overall mission of the Laboratory is to acquire and communicate knowledge of ecological processes and principles. SREL conducts fundamental and applied ecological research, as well as education and outreach programs, under a Cooperative Agreement with the U.S. Department of Energy (DOE) SRS near Aiken, South Carolina. The Laboratory's research mission during the 2001 fiscal year was fulfilled with the publication of one book and 83more » journal articles and book chapters by faculty, technical staff, students, and visiting scientists. An additional 77 journal articles have been submitted or are in press. Other noteworthy events took place as faculty members and graduate students received awards. These are described in the section Special Accomplishments of Faculty, Staff, Students, and Administration on page 54. Notable scientific accomplishments include work conducted on contaminant transport, global reptile decline, phytoremediation, and radioecology. Dr. Domy Adriano authored the second edition of his book ''Trace Elements in Terrestrial Environments: Biogeochemistry, Bioavailability, and Risks of Metals'', which was recently published by Springer-Verlag. The book provides a comprehensive treatment of many important aspects of trace elements in the environment. The first edition of the book, published in 1986, has become a widely acclaimed and cited reference. International attention was focused on the problem of reptile species decline with the publication of an article on this topic in the journal ''Bioscience'' in August, 2000. The article's authors included Dr. Whit Gibbons and a number of other SREL herpetologists who researched the growing worldwide problem of decline of reptile species. Factors related to these declines include habitat loss and

Laboratory directed research and development 2006 annual report.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Westrich, Henry Roger

2007-03-01

This report summarizes progress from the Laboratory Directed Research and Development (LDRD) program during fiscal year 2006. In addition to a programmatic and financial overview, the report includes progress reports from 430 individual R&D projects in 17 categories.

78 FR 28292 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-14

... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board; Notice of Meetings; Amendment The Department of Veterans Affairs (VA) gives notice under the Federal Advisory Committee Act, 5 U.S.C. App...

48 CFR 32.202-3 - Conducting market research about financing terms.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Conducting market research... 32.202-3 Conducting market research about financing terms. Contract financing may be a subject included in the market research conducted in accordance with part 10. If market research for contract...

48 CFR 32.202-3 - Conducting market research about financing terms.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Conducting market research... 32.202-3 Conducting market research about financing terms. Contract financing may be a subject included in the market research conducted in accordance with part 10. If market research for contract...

Case studies identify savings of up to $40,000 for academic research laboratories with the use of video journals

NASA Astrophysics Data System (ADS)

Pritsker, Moshe

2015-04-01

Recent studies indicate that 70% to 90% of results published in science journals are not reproducible, which presents troubling uncertainty about the future of scientific research. In contrast to the text format of traditional journals, novel video-based journals allow for systematic, step-by-step visualized demonstrations of research experiments. Video articles produce a more efficient transfer of knowledge between laboratories and therefore offer a viable solution to the issue of reproducibility. To quantify the savings of time and money generated by this alternative mode of scientific communication, we conducted a number of case studies among academic laboratories who use the peer-reviewed video journal JoVE. One study determined that using video as a guide to learn a new dissection technique saved a bioengineering lab at the University of Washington 40,000. A second case study found that a laboratory at Cornell University studying muscular dystrophy eliminated 6 months of experimentation by learning a new complex stem cell injection technique from the video journal. Results from a third study indicated that a laboratory at the University of Helsinki shortened the time to learn a surgical technique from 1 year to 2 weeks. Together, these studies indicate that video publication significantly enhances the reproducibility and productivity of scientific research.

The Los Alamos Scientific Laboratory - An Isolated Nuclear Research Establishment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bradbury, Norris E.; Meade, Roger Allen

Early in his twenty-five year career as the Director of the Los Alamos Scientific Laboratory, Norris Bradbury wrote at length about the atomic bomb and the many implications the bomb might have on the world. His themes were both technical and philosophical. In 1963, after nearly twenty years of leading the nation’s first nuclear weapons laboratory, Bradbury took the opportunity to broaden his writing. In a paper delivered to the International Atomic Energy Agency’s symposium on the “Criteria in the Selection of Sites for the Construction of Reactors and Nuclear Research Centers,” Bradbury took the opportunity to talk about themore » business of nuclear research and the human component of operating a scientific laboratory. This report is the transcript of his talk.« less

Clinical Nurse Specialist Roles in Conducting Research: Changes Over 3 Years.

PubMed

Albert, Nancy M; Rice, Karen L; Waldo, Mary J; Bena, James F; Mayo, Ann M; Morrison, Shannon L; Westlake, Cheryl; Ellstrom, Kathleen; Powers, Jan; Foster, Jan

2016-01-01

The aim of this study is to describe clinical nurse specialists' characteristics, interest, confidence, motivators, and barriers in conducting research. This study was a descriptive, multicohort design. Clinical nurse specialists were recruited electronically through national and local organizations to complete anonymous surveys 3 times, over 3 years. Comparative analyses included χ and Kruskal-Wallis tests. Of 2052 responders (initial, n = 629; 18 months, n = 465; and 3 years, n = 958), mean (SD) participant age was 50.3 (9.3) years. Overall, 41.7% of participants were involved as principal or coinvestigators in research. Interest in conducting nursing research (on a 0-100 scale) was 61.1 (38.4) and was lowest among the 18-month time point participant group (score, 39.1 [32.2]) and highest at the 3-year time point (68.3, [30.7]; P < .001). Confidence in conducting research, discussion of statistics, and perceptions of motivators and barriers to conducting research did not differ across time period groups. Access to literature and mentors and research knowledge were the most prevalent barriers to conducting research. Less than 42% of clinical nurse specialists conducted research and the rate did not change between different time groups. Access and knowledge barriers to conducting research were prominent. Workplace leaders need to consider resources and support of academic educational opportunities to increase research conduct by clinical nurse specialists.

Unbridle biomedical research from the laboratory cage

PubMed Central

Lahvis, Garet P

2017-01-01

Many biomedical research studies use captive animals to model human health and disease. However, a surprising number of studies show that the biological systems of animals living in standard laboratory housing are abnormal. To make animal studies more relevant to human health, research animals should live in the wild or be able to roam free in captive environments that offer a natural range of both positive and negative experiences. Recent technological advances now allow us to study freely roaming animals and we should make use of them. PMID:28661398

Methodology in diagnostic laboratory test research in clinical chemistry and clinical chemistry and laboratory medicine.

PubMed

Lumbreras-Lacarra, Blanca; Ramos-Rincón, José Manuel; Hernández-Aguado, Ildefonso

2004-03-01

The application of epidemiologic principles to clinical diagnosis has been less developed than in other clinical areas. Knowledge of the main flaws affecting diagnostic laboratory test research is the first step for improving its quality. We assessed the methodologic aspects of articles on laboratory tests. We included articles that estimated indexes of diagnostic accuracy (sensitivity and specificity) and were published in Clinical Chemistry or Clinical Chemistry and Laboratory Medicine in 1996, 2001, and 2002. Clinical Chemistry has paid special attention to this field of research since 1996 by publishing recommendations, checklists, and reviews. Articles were identified through electronic searches in Medline. The strategy combined the Mesh term "sensitivity and specificity" (exploded) with the text words "specificity", "false negative", and "accuracy". We examined adherence to seven methodologic criteria used in the study by Reid et al. (JAMA1995;274:645-51) of papers published in general medical journals. Three observers evaluated each article independently. Seventy-nine articles fulfilled the inclusion criteria. The percentage of studies that satisfied each criterion improved from 1996 to 2002. Substantial improvement was observed in reporting of the statistical uncertainty of indices of diagnostic accuracy, in criteria based on clinical information from the study population (spectrum composition), and in avoidance of workup bias. Analytical reproducibility was reported frequently (68%), whereas information about indeterminate results was rarely provided. The mean number of methodologic criteria satisfied showed a statistically significant increase over the 3 years in Clinical Chemistry but not in Clinical Chemistry and Laboratory Medicine. The methodologic quality of the articles on diagnostic test research published in Clinical Chemistry and Clinical Chemistry and Laboratory Medicine is comparable to the quality observed in the best general medical journals

Pacific Northwest Laboratory annual report for 1992 to the DOE Office of Energy Research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grove, L.K.

1993-03-01

The 1992 Annual Report from Pacific Northwest Laboratory (PNL) to the US Department of Energy (DOE) describes research in environment and health conducted during fiscal year 1992. This report consists of four volumes oriented to particular segments of the PNL program, describing research performed for the DOE Office of Health and Environmental Research in the Office of Energy Research. The parts of the 1992 Annual Report are: Biomedical Sciences; Environmental Sciences; Atmospheric Sciences; and Physical Sciences. This Report is Part II: Environmental Sciences. Included in this report are developments in Subsurface Science, Terrestrial Science, Laboratory-Directed Research and Development, Interactions withmore » Educational Institutions, Technology Transfer, Publications, and Presentations. The research is directed toward developing a fundamental understanding of subsurface and terrestrial systems as a basis for both managing these critical resources and addressing environmental problems such as environmental restoration and global change. The Technology Transfer section of this report describes a number of examples in which fundamental research is laying the groundwork for the technology needed to resolve important environmental problems. The Interactions with Educational Institutions section of the report illustrates the results of a long-term, proactive program to make PNL facilities available for university and preuniversity education and to involve educational institutions in research programs. The areas under investigation include the effect of geochemical and physical phenomena on the diversity and function of microorganisms in deep subsurface environments, ways to address subsurface heterogeneity, and ways to determine the key biochemical and physiological pathways (and DNA markers) that control nutrient, water, and energy dynamics in arid ecosystems and the response of these systems to disturbance and climatic change.« less

The Central Importance of Laboratories for Reducing Waste in Biomedical Research.

PubMed

Stroth, Nikolas

2016-12-01

The global biomedical research enterprise is driving substantial advances in medicine and healthcare. Yet it appears that the enterprise is rather wasteful, falling short of its true innovative potential. Suggested reasons are manifold and involve various stakeholders, such that there is no single remedy. In the present paper, I will argue that laboratories are the basic working units of the biomedical research enterprise and an important site of action for corrective intervention. Keeping laboratories relatively small will enable better training and mentoring of individual scientists, which in turn will yield better performance of the scientific workforce. The key premise of this argument is that people are at the heart of the successes and failures of biomedical research, yet the human dimension of science has been unduly neglected in practice. Renewed focus on the importance of laboratories and their constituent scientists is one promising approach to reducing waste and increasing efficiency within the biomedical research enterprise.

Conducting Science-Based Psychology Research in Schools

ERIC Educational Resources Information Center

Dinella, Lisa M., Ed.

2009-01-01

What are the common pitfalls experienced by school researchers and how can they be avoided? Edited by Lisa M. Dinella of Monmouth University, "Conducting Science-Based Psychology Research in Schools" includes the collective knowledge of both established and emerging names in the field, providing an unparalleled resource for those interested in…

Conducting Research in Schools: A Practical Guide

ERIC Educational Resources Information Center

Alibali, Martha W.; Nathan, Mitchell J.

2010-01-01

Cognitive development unfolds in many contexts, and one of the most important of these contexts is school. Thus, understanding the school context is critical for understanding development. This article discusses some of the reasons why cognitive developmental researchers might wish to conduct research in schools, describes how to get started…

Conducting On-Farm Animal Research: Procedures & Economic Analysis.

ERIC Educational Resources Information Center

Amir, Pervaiz; Knipscheer, Hendrik C.

This book is intended to give animal scientists elementary tools to perform on-farm livestock analysis and to provide crop-oriented farming systems researchers with methods for conducting animal research. Chapter 1 describes farming systems research as a systems approach to on-farm animal research. Chapter 2 outlines some important…

Considerations when conducting e-Delphi research: a case study.

PubMed

Toronto, Coleen

2017-06-22

Background E-Delphi is a way to access a geographically dispersed group of experts. It is similar to other Delphi methods but conducted online. E-research methodologies, such as the e-Delphi method, have yet to undergo significant critical discussion. Aim To highlight some of the challenges nurse researchers may wish to consider when using e-Delphi in their research. Discussion This paper provides details about the author's approach to conducting an e-Delphi study in which a group of health literacy nurse experts (n=41) used an online survey platform to identify and prioritise essential health literacy competencies for registered nurses. Conclusion This paper advances methodological discourse about e-Delphi by critically assessing an e-Delphi case study. The online survey platform used in this study was advantageous for the researcher and the experts: the experts could participate at any time and place where the internet was available; the researcher could efficiently access a national group of experts, track responses and analyse data in each round. Implications for practice E-Delphi studies create opportunities for nurse researchers to conduct research nationally and internationally. Before conducting an e-Delphi study, researchers should carefully consider the design and methods for collecting data, to avoid challenges that could potentially compromise the quality of the findings. Researchers are encouraged to publish details about their approaches to e-Delphi studies, to advance the state of the science.

The NASA Lewis Research Center High Temperature Fatigue and Structures Laboratory

NASA Technical Reports Server (NTRS)

Mcgaw, M. A.; Bartolotta, P. A.

1987-01-01

The physical organization of the NASA Lewis Research Center High Temperature Fatigue and Structures Laboratory is described. Particular attention is given to uniaxial test systems, high cycle/low cycle testing systems, axial torsional test systems, computer system capabilities, and a laboratory addition. The proposed addition will double the floor area of the present laboratory and will be equipped with its own control room.

40 CFR 60.535 - Laboratory accreditation.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Wood Heaters § 60.535 Laboratory accreditation. (a)(1) A laboratory may apply for accreditation by the Administrator to conduct wood heater certification tests pursuant to § 60.533. The application shall be in writing to: Emission Measurement Branch (MD-13), U.S. EPA, Research Triangle Park, NC 27711, Attn: Wood...

40 CFR 60.535 - Laboratory accreditation.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Wood Heaters § 60.535 Laboratory accreditation. (a)(1) A laboratory may apply for accreditation by the Administrator to conduct wood heater certification tests pursuant to § 60.533. The application shall be in writing to: Emission Measurement Branch (MD-13), U.S. EPA, Research Triangle Park, NC 27711, Attn: Wood...

40 CFR 60.535 - Laboratory accreditation.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Wood Heaters § 60.535 Laboratory accreditation. (a)(1) A laboratory may apply for accreditation by the Administrator to conduct wood heater certification tests pursuant to § 60.533. The application shall be in writing to: Emission Measurement Branch (MD-13), U.S. EPA, Research Triangle Park, NC 27711, Attn: Wood...

40 CFR 60.535 - Laboratory accreditation.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Wood Heaters § 60.535 Laboratory accreditation. (a)(1) A laboratory may apply for accreditation by the Administrator to conduct wood heater certification tests pursuant to § 60.533. The application shall be in writing to: Emission Measurement Branch (MD-13), U.S. EPA, Research Triangle Park, NC 27711, Attn: Wood...

40 CFR 60.535 - Laboratory accreditation.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Wood Heaters § 60.535 Laboratory accreditation. (a)(1) A laboratory may apply for accreditation by the Administrator to conduct wood heater certification tests pursuant to § 60.533. The application shall be in writing to: Emission Measurement Branch (MD-13), U.S. EPA, Research Triangle Park, NC 27711, Attn: Wood...

Cryptosporidiosis outbreak at an academic animal research laboratory-Colorado, 2014.

PubMed

Hancock-Allen, Jessica; Alden, Nisha B; Cronquist, Alicia B

2017-02-01

After cryptosporidiosis was reported in three workers caring for preweaned calves at an academic research laboratory, we sought to identify cases, determine risk factors, and implement control measures. A cryptosporidiosis case was defined as diarrhea duration ≥72 hr, abdominal cramps, or vomiting in an animal research laboratory worker during July 14-July 31. A confirmed case had laboratory evidence of Cryptosporidium infection. Staff were interviewed regarding illness, potential exposures, training, and personal protective equipment (PPE) standard operating procedures (SOPs). The cryptosporidiosis attack rate (AR) was 74% (20/27); five were laboratory-confirmed. Median job training was 2 hr including respiratory-fit testing. No SOPs existed for doffing PPE. AR for workers who removed their gloves first was 84% (16/19) compared with 20% (1/5) for workers who removed gloves last (risk ratio = 4.2; P < 0.02). This outbreak highlights the importance of adequate training, enforced proper PPE procedures, and promoting a culture of safety. Am. J. Ind. Med. 60:208-214, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

The NASA Earth Research-2 (ER-2) Aircraft: A Flying Laboratory for Earth Science Studies

NASA Technical Reports Server (NTRS)

Navarro, Robert

2007-01-01

The National Aeronautics and Space Administration Dryden Flight Research Center, Edwards, California, has two Lockheed Martin Corporation (Bethesda, Maryland) Earth Research-2 (ER2) aircraft that serve as high-altitude and long-range flying laboratories. The ER-2 aircraft has been successfully utilized to conduct scientific studies of stratospheric and tropospheric chemistry, land-use mapping, disaster assessment, preliminary testing and calibration and validation of satellite sensors. The research missions for the ER-2 aircraft are planned, implemented, and managed by the Dryden Flight Research Center Science Mission Directorate. Maintenance and instrument payload integration is conducted by Dryden personnel. The ER-2 aircraft provides experimenters with a wide array of payload accommodations areas with suitable environment control with required electrical and mechanical interfaces. Missions may be flown out of Dryden or from remote bases worldwide, according to research requirements. The NASA ER-2 aircraft is utilized by a variety of customers, including U.S. Government agencies, civilian organizations, universities, and state governments. The combination of the ER-2 aircraft s range, endurance, altitude, payload power, payload volume and payload weight capabilities complemented by a trained maintenance and operations team provides an excellent and unique platform system to the science community and other customers.

Challenges of Conducting Systematic Research in Australia's Northern Territory

ERIC Educational Resources Information Center

Helmer, Janet; Harper, Helen; Lea, Tess; Wolgemuth, Jennifer R.; Chalkiti, Kalotina

2014-01-01

This paper explores the challenges of conducting systematic research, using our experiences of conducting a study to evaluate the effectiveness of ABRACADABRA, an online tool for early childhood literacy instruction as the contextual framework. By discussing how the research team resolved such perennial issues as high teacher turnover, low or…

Researcher Perceptions of Ethical Guidelines and Codes of Conduct

PubMed Central

Giorgini, Vincent; Mecca, Jensen T.; Gibson, Carter; Medeiros, Kelsey; Mumford, Michael D.; Connelly, Shane; Devenport, Lynn D.

2014-01-01

Ethical codes of conduct exist in almost every profession. Field-specific codes of conduct have been around for decades, each articulating specific ethical and professional guidelines. However, there has been little empirical research on researchers’ perceptions of these codes of conduct. In the present study, we interviewed faculty members in six research disciplines and identified five themes bearing on the circumstances under which they use ethical guidelines and the underlying reasons for not adhering to such guidelines. We then identify problems with the manner in which codes of conduct in academia are constructed and offer solutions for overcoming these problems. PMID:25635845

Improving validity of informed consent for biomedical research in Zambia using a laboratory exposure intervention.

PubMed

Zulu, Joseph Mumba; Lisulo, Mpala Mwanza; Besa, Ellen; Kaonga, Patrick; Chisenga, Caroline C; Chomba, Mumba; Simuyandi, Michelo; Banda, Rosemary; Kelly, Paul

2014-01-01

Complex biomedical research can lead to disquiet in communities with limited exposure to scientific discussions, leading to rumours or to high drop-out rates. We set out to test an intervention designed to address apprehensions commonly encountered in a community where literacy is uncommon, and where complex biomedical research has been conducted for over a decade. We aimed to determine if it could improve the validity of consent. Data were collected using focus group discussions, key informant interviews and observations. We designed an intervention that exposed participants to a detailed demonstration of laboratory processes. Each group was interviewed twice in a day, before and after exposure to the intervention in order to assess changes in their views. Factors that motivated people to participate in invasive biomedical research included a desire to stay healthy because of the screening during the recruitment process, regular advice from doctors, free medical services, and trust in the researchers. Inhibiting factors were limited knowledge about samples taken from their bodies during endoscopic procedures, the impact of endoscopy on the function of internal organs, and concerns about the use of biomedical samples. The belief that blood can be used for Satanic practices also created insecurities about drawing of blood samples. Further inhibiting factors included a fear of being labelled as HIV positive if known to consult heath workers repeatedly, and gender inequality. Concerns about the use and storage of blood and tissue samples were overcome by a laboratory exposure intervention. Selecting a group of members from target community and engaging them in a laboratory exposure intervention could be a useful tool for enhancing specific aspects of consent for biomedical research. Further work is needed to determine the extent to which improved understanding permeates beyond the immediate group participating in the intervention.

Improving Validity of Informed Consent for Biomedical Research in Zambia Using a Laboratory Exposure Intervention

PubMed Central

Zulu, Joseph Mumba; Lisulo, Mpala Mwanza; Besa, Ellen; Kaonga, Patrick; Chisenga, Caroline C.; Chomba, Mumba; Simuyandi, Michelo; Banda, Rosemary; Kelly, Paul

2014-01-01

Background Complex biomedical research can lead to disquiet in communities with limited exposure to scientific discussions, leading to rumours or to high drop-out rates. We set out to test an intervention designed to address apprehensions commonly encountered in a community where literacy is uncommon, and where complex biomedical research has been conducted for over a decade. We aimed to determine if it could improve the validity of consent. Methods Data were collected using focus group discussions, key informant interviews and observations. We designed an intervention that exposed participants to a detailed demonstration of laboratory processes. Each group was interviewed twice in a day, before and after exposure to the intervention in order to assess changes in their views. Results Factors that motivated people to participate in invasive biomedical research included a desire to stay healthy because of the screening during the recruitment process, regular advice from doctors, free medical services, and trust in the researchers. Inhibiting factors were limited knowledge about samples taken from their bodies during endoscopic procedures, the impact of endoscopy on the function of internal organs, and concerns about the use of biomedical samples. The belief that blood can be used for Satanic practices also created insecurities about drawing of blood samples. Further inhibiting factors included a fear of being labelled as HIV positive if known to consult heath workers repeatedly, and gender inequality. Concerns about the use and storage of blood and tissue samples were overcome by a laboratory exposure intervention. Conclusion Selecting a group of members from target community and engaging them in a laboratory exposure intervention could be a useful tool for enhancing specific aspects of consent for biomedical research. Further work is needed to determine the extent to which improved understanding permeates beyond the immediate group participating in the intervention

Conducting a successful residency research project.

PubMed

Barletta, Jeffrey F

2008-08-15

The residency research project can be a challenging endeavor for pharmacy residents since they typically have limited experience in this area. Furthermore, as the number of accredited residency programs has increased, so has the demand for preceptors with research experience. This review is intended to assist the resident and preceptor by providing steps and guidance with conducting a successful residency research project. Items such as idea generation, proposing the right type of project, departmental review, and project management skills are discussed and guidance with writing the research protocol is provided. Items that must be addressed in every research protocol are described and a generalized protocol template is presented. In addition, the institutional review board review process is described and tips and pointers for obtaining approval are included. Finally, useful tools and resources are provided that can be used up front or throughout each phase of the research project.

The Automated Primate Research Laboratory (APRL)

NASA Technical Reports Server (NTRS)

Pace, N.; Smith, G. D.

1972-01-01

A description is given of a self-contained automated primate research laboratory to study the effects of weightlessness on subhuman primates. Physiological parameters such as hemodynamics, respiration, blood constituents, waste, and diet and nutrition are analyzed for abnormalities in the simulated space environment. The Southeast Asian pig-tailed monkey (Macaca nemistrina) was selected for the experiments owing to its relative intelligence and learning capacity. The objective of the program is to demonstrate the feasibility of a man-tended primate space flight experiment.

Plant and animal accommodation for Space Station Laboratory

NASA Technical Reports Server (NTRS)

Olson, Richard L.; Gustan, Edith A.; Wiley, Lowell F.

1986-01-01

An extended study has been conducted with the goals of defining and analyzing relevant parameters and significant tradeoffs for the accommodation of nonhuman research aboard the NASA Space Station, as well as conducting tradeoff analyses for orbital reconfiguring or reoutfitting of the laboratory facility and developing laboratory designs and program plans. The two items exerting the greatest influence on nonhuman life sciences research were identified as the centrifuge and the specimen environmental control and life support system; both should be installed on the ground rather than in orbit.

From Cookbook to Research: Redesigning an Advanced Biochemistry Laboratory

ERIC Educational Resources Information Center

Boyd-Kimball, Debra; Miller, Keith R.

2018-01-01

Laboratory courses are often designed using step-by-step protocols which encourage students to conduct experiments without thinking about what they are doing or why they are doing it. Such course design limits the growth of our students as scientists and can make it more difficult for a student to transition to the expectations of a research…

Nanotechnology Laboratory Collaborates with Army to Develop Botulism Vaccine | Frederick National Laboratory for Cancer Research

Cancer.gov

The Nanotechnology Characterization Laboratory (NCL) is collaborating with the Army to develop a candidate vaccine against botulism. Under a collaboration agreement between the National Cancer Institute and the U.S. Army Medical Research Institute of

Argonne National Laboratory annual report of Laboratory Directed Research and Development Program Activities FY 2009.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Office of the Director

2010-04-09

I am pleased to submit Argonne National Laboratory's Annual Report on its Laboratory Directed Research and Development (LDRD) activities for fiscal year 2009. Fiscal year 2009 saw a heightened focus by DOE and the nation on the need to develop new sources of energy. Argonne scientists are investigating many different sources of energy, including nuclear, solar, and biofuels, as well as ways to store, use, and transmit energy more safely, cleanly, and efficiently. DOE selected Argonne as the site for two new Energy Frontier Research Centers (EFRCs) - the Institute for Atom-Efficient Chemical Transformations and the Center for Electrical Energymore » Storage - and funded two other EFRCs to which Argonne is a major partner. The award of at least two of the EFRCs can be directly linked to early LDRD-funded efforts. LDRD has historically seeded important programs and facilities at the lab. Two of these facilities, the Advanced Photon Source and the Center for Nanoscale Materials, are now vital contributors to today's LDRD Program. New and enhanced capabilities, many of which relied on LDRD in their early stages, now help the laboratory pursue its evolving strategic goals. LDRD has, since its inception, been an invaluable resource for positioning the Laboratory to anticipate, and thus be prepared to contribute to, the future science and technology needs of DOE and the nation. During times of change, LDRD becomes all the more vital for facilitating the necessary adjustments while maintaining and enhancing the capabilities of our staff and facilities. Although I am new to the role of Laboratory Director, my immediate prior service as Deputy Laboratory Director for Programs afforded me continuous involvement in the LDRD program and its management. Therefore, I can attest that Argonne's program adhered closely to the requirements of DOE Order 413.2b and associated guidelines governing LDRD. Our LDRD program management continually strives to be more efficient. In addition

CSI flight experiment projects of the Naval Research Laboratory

NASA Technical Reports Server (NTRS)

Fisher, Shalom

1993-01-01

The Naval Research Laboratory (NRL) is involved in an active program of CSI flight experiments. The first CSI flight experiment of the Naval Research Laboratory, the Low Power Atmospheric Compensation Experiment (LACE) dynamics experiment, has successfully measured vibrations of an orbiting satellite with a ground-based laser radar. The observations, made on January 7, 8 and 10, 1991, represent the first ever measurements of this type. In the tests, a narrowband heterodyne CO2 laser radar, operating at a wavelength of 10.6 microns, detected vibration induced differential-Doppler signatures of the LACE satellite. Power spectral densities of forced oscillations and modal frequencies and damping rates of free-damped vibrations were obtained and compared with finite element structural models of the LACE system. Another manifested flight experiment is the Advanced Controls Technology Experiment (ACTEX) designed to demonstrate active and passive damping with piezo-electric (PZT) sensors and actuators. This experiment was developed under the management of the Air Force Phillips Laboratory with integration of the experiment at NRL. It is to ride as a secondary, or 'piggyback,' experiment on a future Navy satellite.

CSI flight experiment projects of the Naval Research Laboratory

NASA Astrophysics Data System (ADS)

Fisher, Shalom

1993-02-01

The Naval Research Laboratory (NRL) is involved in an active program of CSI flight experiments. The first CSI flight experiment of the Naval Research Laboratory, the Low Power Atmospheric Compensation Experiment (LACE) dynamics experiment, has successfully measured vibrations of an orbiting satellite with a ground-based laser radar. The observations, made on January 7, 8 and 10, 1991, represent the first ever measurements of this type. In the tests, a narrowband heterodyne CO2 laser radar, operating at a wavelength of 10.6 microns, detected vibration induced differential-Doppler signatures of the LACE satellite. Power spectral densities of forced oscillations and modal frequencies and damping rates of free-damped vibrations were obtained and compared with finite element structural models of the LACE system. Another manifested flight experiment is the Advanced Controls Technology Experiment (ACTEX) designed to demonstrate active and passive damping with piezo-electric (PZT) sensors and actuators. This experiment was developed under the management of the Air Force Phillips Laboratory with integration of the experiment at NRL. It is to ride as a secondary, or 'piggyback,' experiment on a future Navy satellite.

Educational-research laboratory "electric circuits" on the base of digital technologies

NASA Astrophysics Data System (ADS)

Koroteyev, V. I.; Florentsev, V. V.; Florentseva, N. I.

2017-01-01

The problem of research activity of trainees' activation in the educational-research laboratory "Electric Circuits" using innovative methodological solutions and digital technologies is considered. The main task is in creation of the unified experimental research information-educational environment "Electrical Engineering". The problems arising during the developing and application of the modern software and hardware, experimental and research stands and digital control and measuring systems are presented. This paper presents the main stages of development and creation of educational-research laboratory "Electrical Circuits" at the Department of Electrical Engineering of NRNU MEPhI. The authors also consider the analogues of the described research complex offered by various educational institutions and companies. The analysis of their strengths and weaknesses, on which the advantages of the proposed solution are based, is held.

National Research Council Research Associateships Program with Methane Hydrates Fellowships Program/National Energy Technology Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Basques, Eric O.

2014-03-20

This report summarizes work carried out over the period from July 5, 2005-January 31, 2014. The work was carried out by the National Research Council Research Associateships Program of the National Academies, under the US Department of Energy's National Energy Technology Laboratory (NETL) program. This Technical Report consists of a description of activity from 2005 through 2014, broken out within yearly timeframes, for NRC/NETL Associateships researchers at NETL laboratories which includes individual tenure reports from Associates over this time period. The report also includes individual tenure reports from associates over this time period. The report also includes descriptions of programmore » promotion efforts, a breakdown of the review competitions, awards offered, and Associate's activities during their tenure.« less

Strategic Plan for the ORD National Exposure Research Laboratory (NERL)

EPA Science Inventory

The National Exposure Research Laboratory (NERL) has a valued reputation for supporting the Agency’s mission of protecting human health and the environment with multidisciplinary expertise that brings cutting-edge research and technology to address critical exposure questions and...

Intelligent Intersection Traffic Control Laboratory Fact Sheet

DOT National Transportation Integrated Search

2006-07-27

The Intelligent Intersection 11:affic Control Laboratory (IITCL) is an outdoor facility that supports the Federal Highway Administration's (FHWA) various research programs and research activities conducted by other U.S. Department of 11:ansportation ...

Radar research at The Pennsylvania State University Radar and Communications Laboratory

NASA Astrophysics Data System (ADS)

Narayanan, Ram M.

2017-05-01

The Radar and Communications Laboratory (RCL) at The Pennsylvania State University is at the forefront of radar technology and is engaged in cutting edge research in all aspects of radar, including modeling and simulation studies of novel radar paradigms, design and development of new types of radar architectures, and extensive field measurements in realistic scenarios. This paper summarizes the research at The Pennsylvania State University's Radar and Communications Laboratory and relevant collaborative research with several groups over the past 15 years in the field of radar and related technologies, including communications, radio frequency identification (RFID), and spectrum sensing.

Conducting Research: A Handbook for School Social Workers.

ERIC Educational Resources Information Center

McCullagh, James G., Ed.; Allen-Meares, Paula, Ed.

This handbook on conducting research was written for school social workers and contains these articles: (1) "The School Social Work Practitioner and Research: An Overview" (Elizabeth Timberlake and Lewis Carr); (2) "Defining Empirically Based Practice" (Deborah Siegel); (3) "Future Research in School Social Work Services: An Update" (Christine…

NATIONAL HEALTH AND ENVIRONMENTAL EFFECTS RESEARCH LABORATORY - ACCOMPLISHMENTS FOR FY 2001

EPA Science Inventory

This Annual Report showcases some of the scientific activities of the National Health and Environmental Effects Research Laboratory (NHEERL) in various health and environmental effects research areas. Where appropriate, the contributions of other collaborating research organizat...

Safety Issues in Agricultural Education Laboratories: A Synthesis of Research.

ERIC Educational Resources Information Center

Dyer, James E.; Andreasen, Randall J.

1999-01-01

Synthesis of research on safety in agricultural education laboratories found most research focused on agricultural mechanics. Labs appeared to be potentially hazardous places, and teachers have inadequate knowledge of safety laws and ways to provide a safe working environment. (SK)

STAR: Preparing future science and math teachers through authentic research experiences at national laboratories

NASA Astrophysics Data System (ADS)

Keller, John; Rebar, Bryan

2012-11-01

The STEM Teacher and Researcher (STAR) Program provides 9-week paid summer research experiences at national research laboratories for future science and math teachers. The program, run by the Cal Poly Center for Excellence in Science and Mathematics Education (CESaME) on behalf of the entire California State University (CSU) System, has arranged 290 research internships for 230 STEM undergraduates and credential candidates from 43 campuses over the past 6 years. The program has partnered with seven Department of Energy labs, four NASA centers, three NOAA facilities, and the National Optical Astronomy Observatory (NOAO). Primary components of the summer experience include a) conducting research with a mentor or mentor team, b) participating in weekly 2-3 hour workshops focused on translating lessons learned from summer research into classroom practice, and c) presenting a research poster or oral presentation and providing a lesson plan linked to the summer research experience. The central premise behind the STAR Program is that future science and math teachers can more effectively prepare the next generation of science, math, and engineering students if they themselves have authentic experiences as researchers.

A Hybrid Integrated Laboratory and Inquiry-Based Research Experience: Replacing Traditional Laboratory Instruction with a Sustainable Student-Led Research Project

ERIC Educational Resources Information Center

Hartings, Matthew R.; Fox, Douglas M.; Miller, Abigail E.; Muratore, Kathryn E.

2015-01-01

The Department of Chemistry at American University has replaced its junior- and senior-level laboratory curriculum with two, two-semester long, student-led research projects as part of the department's American Chemical Society-accredited program. In the first semester of each sequence, a faculty instructor leads the students through a set of…

Challenges in Conducting Qualitative Research with Persons with Dementia

PubMed Central

Beuscher, Linda; Grando, Victoria T.

2010-01-01

Qualitative research can capture the meaningful experiences and life values of persons with dementia not reported in quantitative studies. This researcher shares personal experience of the challenges faced and the lessons learned while conducting a qualitative study of 15 persons with early stage Alzheimer’s disease. The purpose of this paper is to discuss the issues concerning determination of capacity to consent to research, consent/assent, communication challenges, and trustworthiness of data when conducting a qualitative study of persons with dementia. Understanding communication challenges due to dementia is important to develop effective communication strategies, such as simplifying the structure of questions, allowing ample time for participant’s response, using reminiscence, and redirecting the dialogue. This information will be valuable to researchers conducting future qualitative studies and the resulting contributions to the body of knowledge about Alzheimer’s PMID:20077988

LABORATORY DIRECTED RESEARCH AND DEVELOPMENT ANNUAL REPORT TO THE DEPARTMENT OF ENERGY - DECEMBER 2006

DOE Office of Scientific and Technical Information (OSTI.GOV)

FOX, K.J.

Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's total annual budget has averaged about $460 million. There are about 2,500 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE)more » annually in March, as required by DOE Order 413.2B, ''Laboratory Directed Research and Development,'' April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy National Nuclear Security Administration Laboratories dated June 13, 2006. In accordance this is our Annual Report in which we describe the Purpose, Approach, Technical Progress and Results, and Specific Accomplishments of all LDRD projects that received funding during Fiscal Year 2006.« less

How To Conduct Collaborative Action Research.

ERIC Educational Resources Information Center

Sagor, Richard

Collaborative action research, conducted by teams of practitioners, is a process that enables teachers: (1) to improve student learning, (2) to improve their own practice, (3) to contribute to the development of their own profession, and (4) to overcome the isolation commonly experienced by classroom teachers. By promoting collegial relationships…

LDRD 2013 Annual Report: Laboratory Directed Research and Development Program Activities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bookless, W.

This LDRD project establishes a research program led by Jingguang Chen, who has started a new position as a Joint Appointee between BNL and Columbia University as of FY2013. Under this project, Dr. Chen will establish a new program in catalysis science at BNL and Columbia University. The LDRD program will provide initial research funding to start research at both BNL and Columbia. At BNL, Dr. Chen will initiate laboratory research, including hiring research staff, and will collaborate with the existing BNL catalysis and electrocatalysis research groups. At Columbia, a subcontract to Dr. Chen will provide startup funding for hismore » laboratory research, including initial graduate student costs. The research efforts will be linked under a common Catalysis Program in Sustainable Fuels. The overall impact of this project will be to strengthen the BNL catalysis science program through new linked research thrusts and the addition of an internationally distinguished catalysis scientist.« less

Laboratory directed research and development program FY 1997

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-03-01

This report compiles the annual reports of Laboratory Directed Research and Development projects supported by the Berkeley Lab. Projects are arranged under the following topical sections: (1) Accelerator and fusion research division; (2) Chemical sciences division; (3) Computing Sciences; (4) Earth sciences division; (5) Environmental energy technologies division; (6) life sciences division; (7) Materials sciences division; (8) Nuclear science division; (9) Physics division; (10) Structural biology division; and (11) Cross-divisional. A total of 66 projects are summarized.

Conducting survey research at nursing conferences.

PubMed

Sleutel, M R

2001-01-01

Conferences can provide large numbers of potential subjects in one location, yet there is little published guidance on how to collect data at a conference site. A computer search revealed no citations on this topic. This article outlines a systematic strategy to plan and perform research at conferences. This article provides a step-by-step process to guide researchers in planning and conducting survey research at conferences. Initial components in planning data collection at a conference include making a timeline and getting permission. Detailed advanced planning involves specific strategies for attracting participants, and for distributing and collecting the questionnaires. Travel provisions and on-site logistical approaches are explained, followed by suggestions for post-conference activities.

Identifying and Addressing Challenges to Research in University Laboratory Preschools

ERIC Educational Resources Information Center

File, Nancy

2012-01-01

Research Findings: This essay offers a review of challenges that university laboratory preschools face in providing a site for research that fits with other components of the program mission. An argument is made to consider paradigm shifts in research questions and methods that move away from traditions within the fields that study children's…

General Henry Arnold Visits the Aircraft Engine Research Laboratory

NASA Image and Video Library

1944-11-21

General Henry “Hap” Arnold, Commander of the US Army Air Forces during World War II, addresses the staff at the National Advisory Committee for Aeronautics (NACA) Aircraft Engine Research Laboratory on November 9, 1944. Arnold told the employees assembled in the hangar, “You’ve got a dual task. You’ve got a job ahead of you to keep the army and the navy air forces equipped with the finest equipment that you can for this war. You also have the job of looking forward into the future and starting now those developments, those experiments, that are going to keep us in our present situation—ahead of the world in the air. And that is quite a large order, and I leave it right in your laps.” Arnold served on the NACA’s Executive Committee in Washington from 1938 to 1944 and had been a strong advocate for the creation of the new engine research facility in Cleveland. Arnold believed in continual research and development. He pressed the nation’s aviation leaders to pursue the new jet engine technology, while simultaneously pushing to increase the performance of the nation’s largest piston engine for the B–29 Superfortress program. The general’s hectic wartime agenda limited his visit to the Cleveland laboratory to just a few hours, but he toured several of the NACA’s new test facilities including the Static Jet Propulsion Laboratory, the Icing Research Tunnel, and a B–24 Liberator in the hangar.

Conducting collaborative abortion research in international settings.

PubMed

Gipson, Jessica D; Becker, Davida; Mishtal, Joanna Z; Norris, Alison H

2011-01-01

Nearly 20% of the 208 million pregnancies that occur annually are aborted. More than half of these (21.6 million) are unsafe, resulting in 47,000 abortion-related deaths each year. Accurate reports on the prevalence of abortion, the conditions under which it occurs, and the experiences women have in obtaining abortions are essential to addressing unsafe abortion globally. It is difficult, however, to obtain accurate and reliable reports of attitudes and practices given that abortion is often controversial and stigmatized, even in settings where it is legal. To improve the understanding and measurement of abortion, specific considerations are needed throughout all stages of the planning, design, and implementation of research on abortion: Establishment of strong local partnerships, knowledge of local culture, integration of innovative methodologies, and approaches that may facilitate better reporting. This paper draws on the authors' collaborative research experiences conducting abortion-related studies using clinic- and community-based samples in five diverse settings (Poland, Zanzibar, Mexico City, the Philippines, and Bangladesh). The purpose of this paper is to share insights and lessons learned with new and established researchers to inform the development and implementation of abortion-related research. The paper discusses the unique challenges of conducting abortion-related research and key considerations for the design and implementation of abortion research, both to maximize data quality and to frame inferences from this research appropriately. Copyright © 2011 Jacobs Institute of Women's Health. Published by Elsevier Inc. All rights reserved.

Variable conductance heat pipe technology

NASA Technical Reports Server (NTRS)

Marcus, B. D.; Edwards, D. K.; Anderson, W. T.

1973-01-01

Research and development programs in variable conductance heat pipe technology were conducted. The treatment has been comprehensive, involving theoretical and/or experimental studies in hydrostatics, hydrodynamics, heat transfer into and out of the pipe, fluid selection, and materials compatibility, in addition to the principal subject of variable conductance control techniques. Efforts were not limited to analytical work and laboratory experimentation, but extended to the development, fabrication and test of spacecraft hardware, culminating in the successful flight of the Ames Heat Pipe Experiment on the OAO-C spacecraft.

Guidelines on Good Clinical Laboratory Practice

PubMed Central

Ezzelle, J.; Rodriguez-Chavez, I. R.; Darden, J. M.; Stirewalt, M.; Kunwar, N.; Hitchcock, R.; Walter, T.; D’Souza, M. P.

2008-01-01

A set of Good Clinical Laboratory Practice (GCLP) standards that embraces both the research and clinical aspects of GLP were developed utilizing a variety of collected regulatory and guidance material. We describe eleven core elements that constitute the GCLP standards with the objective of filling a gap for laboratory guidance, based on IND sponsor requirements, for conducting laboratory testing using specimens from human clinical trials. These GCLP standards provide guidance on implementing GLP requirements that are critical for laboratory operations, such as performance of protocol-mandated safety assays, peripheral blood mononuclear cell processing and immunological or endpoint assays from biological interventions on IND-registered clinical trials. The expectation is that compliance with the GCLP standards, monitored annually by external audits, will allow research and development laboratories to maintain data integrity and to provide immunogenicity, safety, and product efficacy data that is repeatable, reliable, auditable and that can be easily reconstructed in a research setting. PMID:18037599

A 13-week research-based biochemistry laboratory curriculum.

PubMed

Lefurgy, Scott T; Mundorff, Emily C

2017-09-01

Here, we present a 13-week research-based biochemistry laboratory curriculum designed to provide the students with the experience of engaging in original research while introducing foundational biochemistry laboratory techniques. The laboratory experience has been developed around the directed evolution of an enzyme chosen by the instructor, with mutations designed by the students. Ideal enzymes for this curriculum are able to be structurally modeled, solubly expressed, and monitored for activity by UV/Vis spectroscopy, and an example curriculum for haloalkane dehalogenase is given. Unique to this curriculum is a successful implementation of saturation mutagenesis and high-throughput screening of enzyme function, along with bioinformatics analysis, homology modeling, structural analysis, protein expression and purification, polyacrylamide gel electrophoresis, UV/Vis spectroscopy, and enzyme kinetics. Each of these techniques is carried out using a novel student-designed mutant library or enzyme variant unique to the lab team and, importantly, not described previously in the literature. Use of a well-established set of protocols promotes student data quality. Publication may result from the original student-generated hypotheses and data, either from the class as a whole or individual students that continue their independent projects upon course completion. © 2017 by The International Union of Biochemistry and Molecular Biology, 45(5):437-448, 2017. © 2017 The International Union of Biochemistry and Molecular Biology.

Through Microgravity and Towards the Stars: Microgravity and Strategic Research at Marshall's Biological and Physical Space Research Laboratory

NASA Technical Reports Server (NTRS)

Curreri, Peter A.

2003-01-01

The Microgravity and Strategic research at Marshall s Biological and Physical Space Research Laboratory will be reviewed. The environment in orbit provides a unique opportunity to study Materials Science and Biotechnology in the absence of sedimentation and convection. There are a number of peer-selected investigations that have been selected to fly on the Space Station that have been conceived and are led by Marshall s Biological and Physical Research Laboratory s scientists. In addition to Microgravity research the Station will enable research in "Strategic" Research Areas that focus on enabling humans to live, work, and explore the solar system safely. New research in Radiation Protection, Strategic Molecular Biology, and In-Space Fabrication will be introduced.

NATIONAL RISK MANAGEMENT RESEARCH LABORATORY: PROVIDING SOLUTIONS FOR A BETTER TOMORROW

EPA Science Inventory

This small, two-fold flyer contains general information introducing EPA's National Risk Management Research Laboratory and its research program. The key overarching areas of research described are: Protection of drinking water; control of air pollution; pollution prevention and e...

Biological and Environmental Research Program at Oak Ridge National Laboratory, FY 1992--1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

This report is the 1992--1994 Program Director's Overview Report for Oak Ridge National Laboratory's (ORNL's) Biological and Environmental Research (BER) Program, and as such it addresses KP-funded work at ORNL conducted during FY 1991 and in progress during FY 1992; it also serves as a planning document for the remainder of FY 1992 through FY 1994. Non-BER funded work at ORNL relevant to the mission of OHER is also discussed. The second section of the report describes ORNL facilities and resources used by the BER program. The third section addresses research management practices at ORNL. The fourth, fifth, and sixthmore » sections address BER-funded research in progress, program accomplishments and research highlights, and program orientation for the remainder of FY 1992 through FY 1994, respectively. Work for non-BER sponsors is described in the seventh section, followed by a discussion of significant near and long-term issues facing BER work at ORNL in the eighth section. The last section provides a statistical summary of BER research at ORNL. Appendices supplement the above topics with additional detail.« less

Frederick National Laboratory, National Cancer Institute of Mexico to Offer Training Fellowships | Frederick National Laboratory for Cancer Research

Cancer.gov

FREDERICK, Md. -- The Frederick National Laboratory for Cancer Research will extend its scientific mentoring across international borders for the first time by offering postdoctoral research fellowships to scientists under an agreement with the Nati

Avoiding biohazards in medical, veterinary and research laboratories.

PubMed

Grizzle, W E; Fredenburgh, J

2001-07-01

Personnel in medical, veterinary or research laboratories may be exposed to a wide variety of pathogens that range from deadly to debilitating. For some of these pathogens, no treatment is available, and in other cases the treatment does not fully control the disease. It is important that personnel in laboratories that process human or microbiological specimens follow universal precautions when handling tissues, cells, or microbiological specimens owing to the increasing numbers of individuals infected with hepatitis C and HIV in the US and the possibility that an individual may be asymptomatic when a specimen is obtained. Similar precautions must be followed in laboratories that use animal tissues owing to the possibility of exposure to agents that are pathogenic in humans. Personnel with conditions associated with immunosuppression should evaluate carefully whether or not specific laboratory environments put them at increased risk of disease. We offer here some general approaches to identifying biohazards and to minimizing the potential risk of exposure. The issues discussed can be used to develop a general safety program as required by regulatory or accrediting agencies, including the Occupational Safety and Health Administration.

Effects of light at night on laboratory animals and research outcomes.

PubMed

Emmer, Kathryn M; Russart, Kathryn L G; Walker, William H; Nelson, Randy J; DeVries, A Courtney

2018-06-28

Light has substantial influences on the physiology and behavior of most laboratory animals. As such, lighting conditions within animal rooms are potentially significant and often underappreciated variables within experiments. Disruption of the light/dark cycle, primarily by exposing animals to light at night (LAN), disturbs biological rhythms and has widespread physiological consequences because of mechanisms such as melatonin suppression, sympathetic stimulation, and altered circadian clock gene expression. Thus, attention to the lighting environment of laboratory animals and maintaining consistency of a light/dark cycle is imperative for study reproducibility. Light intensity, as well as wavelength, photoperiod, and timing, are all important variables. Although modern rodent facilities are designed to facilitate appropriate light cycling, there are simple ways to modify rooms to prevent extraneous light exposure during the dark period. Attention to lighting conditions of laboratory animals by both researchers and research care staff ensures best practices for maintaining animal welfare, as well as reproducibility of research results. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Laboratory directed research and development. FY 1995 progress report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vigil, J.; Prono, J.

1996-03-01

This document presents an overview of Laboratory Directed Research and Development Programs at Los Alamos. The nine technical disciplines in which research is described include materials, engineering and base technologies, plasma, fluids, and particle beams, chemistry, mathematics and computational science, atmic and molecular physics, geoscience, space science, and astrophysics, nuclear and particle physics, and biosciences. Brief descriptions are provided in the above programs.

Human Toxocariasis: Prevalence and Factors Associated with Biosafety in Research Laboratories

PubMed Central

Mattos, Gabriela Torres; dos Santos, Paula Costa; Telmo, Paula de Lima; Berne, Maria Elisabeth Aires; Scaini, Carlos James

2016-01-01

Human toxocariasis is a neglected parasitic disease worldwide. Researchers studying this disease use infectious strains of Toxocara for experiments. Health workers are at risk in the course of their daily routine and must adhere to biosafety standards while carrying out the activities. Researchers on biosafety concerning working with these parasites are insufficient. The aim of this study was to determine the rate of seroprevalence of Toxocara species among health-care research laboratory workers (professors, technicians, and students), and to investigate the risk factors of Toxocara infection associated with laboratory practices. This cross-sectional study involved 74 researchers at two federal universities in southern Brazil from February 2014 to February 2015; 29 researchers manipulated infective strains of Toxocara canis (test group) and 45 did not (control group). Serum samples were examined using enzyme-linked immunosorbent assay. Epidemiological data were obtained via a questionnaire containing information about laboratory routine, eating behavior, and contact with dogs. The seroprevalence of anti-T. canis IgG was 14.9% (11/74; 13.8% [4/29] in the test group and 15.6% [7/45] in the control group). Most individuals in the test group correctly understood the primary mode of infection; however, 13.8% did not use gloves while manipulating T. canis eggs. Knowledge of biosafety must be well understood by health-care professionals doing laboratory work with biological agents. To our knowledge, this is the first study to investigate the rate of seroprevalence of IgG against Toxocara spp. among professionals and students who handle infective forms of the nematode T. canis. PMID:27698276

Getting started in research: designing and preparing to conduct a research study.

PubMed

Macfarlane, Matthew D; Kisely, Steve; Loi, Samantha; Macfarlane, Stephen; Merry, Sally; Parker, Stephen; Power, Brian; Siskind, Dan; Smith, Geoff; Looi, Jeffrey C

2015-02-01

To discuss common pitfalls and useful tips in designing a quantitative research study, the importance and process of ethical approval, and consideration of funding. Through careful planning, based on formulation of a research question, early career researchers can design and conduct quantitative research projects within the framework of the Scholarly Project or in their own independent projects. © The Royal Australian and New Zealand College of Psychiatrists 2014.

Redefining Authentic Research Experiences in Introductory Biology Laboratories and Barriers to Their Implementation

ERIC Educational Resources Information Center

Spell, Rachelle M.; Guinan, Judith A.; Miller, Kristen R.; Beck, Christopher W.

2014-01-01

Incorporating authentic research experiences in introductory biology laboratory classes would greatly expand the number of students exposed to the excitement of discovery and the rigor of the scientific process. However, the essential components of an authentic research experience and the barriers to their implementation in laboratory classes are…

Introducing Students to Psychological Research: General Psychology as a Laboratory Course

ERIC Educational Resources Information Center

Thieman, Thomas J.; Clary, E. Gil; Olson, Andrea M.; Dauner, Rachel C.; Ring, Erin E.

2009-01-01

For 6 years, we have offered an integrated weekly laboratory focusing on research methods as part of our general psychology course. Through self-report measures and controlled comparisons, we found that laboratory projects significantly increase students' knowledge and comfort level with scientific approaches and concepts, sustain interest in…

Laboratory of Viral Diseases Guest Researcher Seminar Series | Center for Cancer Research

Cancer.gov

Laboratory of Viral Diseases Guest Researcher Seminar Series New Epigenetic Regulators of HIV Latency Speaker: Melanie Ott, M.D., Ph.D, Senior Investigator & Professor of Medicine Gladstone Institutes & University of California Building 33, Main Conference Room 1N09 Main NIH CAMPUS *BLDG 33 is a secure facility, please allow time to pass through security.

Zoonoses of occupational health importance in contemporary laboratory animal research.

PubMed

Hankenson, F Claire; Johnston, Nancy A; Weigler, Benjamin J; Di Giacomo, Ronald F

2003-12-01

In contemporary laboratory animal facilities, workplace exposure to zoonotic pathogens, agents transmitted to humans from vertebrate animals or their tissues, is an occupational hazard. The primary (e.g., macaques, pigs, dogs, rabbits, mice, and rats) and secondary species (e.g., sheep, goats, cats, ferrets, and pigeons) of animals commonly used in biomedical research, as classified by the American College of Laboratory Animal Medicine, are established or potential hosts for a large number of zoonotic agents. Diseases included in this review are principally those wherein a risk to biomedical facility personnel has been documented by published reports of human cases in laboratory animal research settings, or under reasonably similar circumstances. Diseases are listed alphabetically, and each section includes information about clinical disease, transmission, occurrence, and prevention in animal reservoir species and humans. Our goal is to provide a resource for veterinarians, health-care professionals, technical staff, and administrators that will assist in the design and on-going evaluation of institutional occupational health and safety programs.

Stirling Research Laboratory Providing Independent Performance Verification of Convertors for a Stirling Radioisotope Generator

NASA Technical Reports Server (NTRS)

Thieme, Lanny G.

2002-01-01

The Department of Energy (DOE), Germantown, Maryland, Stirling Technology Company (STC), Kennewick, Washington, and NASA Glenn Research Center are developing a free-piston Stirling convertor for a high-efficiency Stirling Radioisotope Generator for NASA Space Science missions. This generator is being developed for multimission use, including providing electric power for unmanned Mars rovers and for deep space missions. STC is developing the 55-W Technology Demonstration Convertor (TDC) under contract to DOE. Glenn is conducting an in-house technology project to assist in developing the convertor for readiness for space qualification and mission implementation. As part of this effort, a Stirling Research Laboratory was established to test the TDC's and related technologies. A key task is providing an independent verification and validation of the TDC performance. Four TDC's are now being tested at Glenn. Acceptance testing has been completed for all convertors, and in general, performance agreed well with that achieved by STC prior to the delivery of the convertors. Performance mapping has also been completed on two of the convertors over a range of hot-end temperatures (450 to 650 C), cold-end temperatures (80 to 120 C), and piston amplitudes (5.2 to 6.2 mm). These test data are available online at http://www.grc.nasa.gov/WWW/tmsb/. The TDC's can be tested in either a horizontal orientation with dual-opposed convertors or in a vertical orientation with a single convertor. Synchronized dual-opposed pairs are used for dynamically balanced operation that results in very low levels of vibration. The Stirling Research Laboratory also supports launch environment testing of the TDC's in Glenn's Structural Dynamics Laboratory and electromagnetic interference and electromagnetic compatibility characterization and reduction efforts. In addition, the TDC's will be used for long-term endurance testing, and preparations are underway for unattended operation.

Exploratory Advanced Research Program : Research Associates Program 2014

DOT National Transportation Integrated Search

2014-12-31

Since 1954, the National Research Council (NRC) has conducted the Research Associateship Program (RAP) in cooperation with sponsoring Federal laboratories and other approved participating research organizations. RAP provides highly skilled and exceed...

Exploratory Advanced Research Program : Research Associates Program 2016

DOT National Transportation Integrated Search

2017-02-01

Since 1954, the National Research Council (NRC) has conducted the Research Associateship Program (RAP) in cooperation with sponsoring Federal laboratories and other approved participating research organizations. RAP provides highly skilled and exceed...

Conducting Quantitative Medical Education Research: From Design to Dissemination.

PubMed

Abramson, Erika L; Paul, Caroline R; Petershack, Jean; Serwint, Janet; Fischel, Janet E; Rocha, Mary; Treitz, Meghan; McPhillips, Heather; Lockspeiser, Tai; Hicks, Patricia; Tewksbury, Linda; Vasquez, Margarita; Tancredi, Daniel J; Li, Su-Ting T

2018-03-01

Rigorous medical education research is critical to effectively develop and evaluate the training we provide our learners. Yet many clinical medical educators lack the training and skills needed to conduct high-quality medical education research. We offer guidance on conducting sound quantitative medical education research. Our aim is to equip readers with the key skills and strategies necessary to conduct successful research projects, highlighting new concepts and controversies in the field. We utilize Glassick's criteria for scholarship as a framework to discuss strategies to ensure that the research question of interest is worthy of further study and how to use existing literature and conceptual frameworks to strengthen a research study. Through discussions of the strengths and limitations of commonly used study designs, we expose the reader to particular nuances of these decisions in medical education research and discuss outcomes generally focused on, as well as strategies for determining the significance of consequent findings. We conclude with information on critiquing research findings and preparing results for dissemination to a broad audience. Practical planning worksheets and comprehensive tables illustrating key concepts are provided in order to guide researchers through each step of the process. Medical education research provides wonderful opportunities to improve how we teach our learners, to satisfy our own intellectual curiosity, and ultimately to enhance the care provided to patients. Copyright © 2018 Academic Pediatric Association. Published by Elsevier Inc. All rights reserved.

Lawrence Livermore National Laboratory FY 2016 Laboratory Directed Research and Development Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Al-Ayat, R.; Gard, E.; Sketchley, J.

The LDRD annual report for FY2016 consists of two parts: The Overview. This section contains a broad description of the LDRD Program, highlights of recent accomplishments and awards, Program statistics, and the LDRD portfolio-management processes. Project Reports. Project reports are submitted by all principal investigators at the end of the fiscal year. The length and depth of the report depends on the project’s lifecycle. For projects that will be continuing the following year, the principal investigator submits a continuing project report, which is a brief update containing descriptions of the goals, scope, motivation, relevance (to DOE/NNSA and Livermore mission areas),more » and technical progress achieved in FY16, as well as a list of selected publications and presentations that resulted from the research. For projects that concluded in FY16, a more detailed final report is provided that is technical in nature and includes the background, objectives, scientific approach, accomplishments, and impacts on the Laboratory missions, as well as a list of publications and presentations that resulted from the research. Project reports are listed under their research topics and organized by year and type, such as exploratory research (ER), feasibility study (FS), laboratory-wide competition (LW), and strategic initiative (SI). Each project is assigned a unique tracking code, an identifier that consists of three elements. The first is the fiscal year in which the project began, the second represents the project type, and the third identifies the serial number of the project for that fiscal year. For example, 16-ERD-100 means the project is an exploratory research project that began in FY16. The three-digit number (100) represents the serial number for the project.« less

What We Do | Frederick National Laboratory for Cancer Research

Cancer.gov

The Frederick National Laboratory is the only U.S. national lab wholly focused on research, technology, and collaboration in the biomedical sciences- working to discover, to innovate, and to improve human health. We accelerate progress against can

Establishment of a Laboratory for Biofuels Research at the University of Kentucky

DOE Office of Scientific and Technical Information (OSTI.GOV)

Crocker, Mark; Crofcheck, Czarena; Andrews, Rodney

2013-03-29

This project was aimed at the development of the biofuels industry in Kentucky by establishing a laboratory to develop improved processes for biomass utilization. The facility is based at the University of Kentucky Center for Applied Energy Research and the Department of Biosystems and Agricultural Engineering, and constitutes an “open” laboratory, i.e., its equipment is available to other Kentucky researchers working in the area. The development of this biofuels facility represents a significant expansion of research infrastructure, and will provide a lasting resource for biobased research endeavors at the University of Kentucky. In order to enhance the laboratory's capabilities andmore » contribute to on-going biofuels research at the University of Kentucky, initial research at the laboratory has focused on the following technical areas: (i) the identification of algae strains suitable for oil production, utilizing flue gas from coal-fired power plants as a source of CO 2; (ii) the conversion of algae to biofuels; and (iii) the development of methods for the analysis of lignin and its deconstruction products. Highlights from these activities include the development of catalysts for the upgrading of lipids to hydrocarbons by means of decarboxylation/decarbonylation (deCOx), a study of bio-oil production from the fast pyrolysis of algae (Scenedesmus), and the application of pyrolytic gas chromatography coupled with mass spectrometry (Py-GC-MS) to the characterization of high lignin biomass feedstocks.« less

Pre-Service Science Teachers' Understandings of Classroom Research and the Problems in Conducting Classroom Research Projects

ERIC Educational Resources Information Center

Jantarakantee, Ekgapoom; Roadrangka, Vantipa; Clarke, Anthony

2012-01-01

This research paper explores pre-service science teachers' understandings of classroom research, problems in conducting classroom research and the supports that pre-service science teachers need from their cooperating teachers to help them conduct a classroom research project during the internship period. The participants in this study are 19…