Laboratory experiments of relevance to the space station environment

NASA Technical Reports Server (NTRS)

Caledonia, G. E.

1988-01-01

It has been found that the interaction between orbital vehicles and the ambient environment produces a contaminant cloud which can cause deletrious effects to spacecraft materials and equipment, create increased radiative backgrounds that would interfere with observational instrumentation, and enhance surface charging. A brief overview of the phenomena that produce the contaminant cloud is presented along with a review of physical data required to characterize it. Laboratory techniques which can be utilized to provide the required data are described. In particular, several oxygen beam apparati are discussed.

Gender specific gene-environment interactions on laboratory-assessed aggression.

PubMed

Verona, Edelyn; Joiner, Thomas E; Johnson, Frank; Bender, Theodore W

2006-01-01

We examined gene-environment interactive effects on aggressive behavior among men and women genotyped (short versus long alleles) for the serotonin transporter gene. Aggressive behavior was indexed via a laboratory paradigm that measured the intensity and duration of shocks delivered to a putative "employee". Half of the participants were exposed to a physical stressor during the procedure (stress) and half were not (no-stress). Participants' physiological responses were gauged via acoustic startle eyeblink reactions (startle reactivity). Results were that men with the homozygous short (s/s) genotype showed increased aggression only under stress, whereas women and men carrying the long allele did not show differences in aggression in stress versus no-stress. However, although stress exposure produced increases in startle reactivity, there were no genotype or gender differences in physiology. These results replicate longitudinal research findings confirming the interactive effects of genes and environment on behavioral reactivity and on the development of externalizing psychopathological syndromes, at least in men.

Conceptualization, Development and Validation of an Instrument for Investigating Elements of Undergraduate Physics Laboratory Learning Environments: The UPLLES (Undergraduate Physics Laboratory Learning Environment Survey)

ERIC Educational Resources Information Center

Thomas, Gregory P; Meldrum, Al; Beamish, John

2013-01-01

First-year undergraduate physics laboratories are important physics learning environments. However, there is a lack of empirically informed literature regarding how students perceive their overall laboratory learning experiences. Recipe formats persist as the dominant form of instructional design in these sites, and these formats do not adequately…

The natural space environment: Effects on spacecraft

NASA Technical Reports Server (NTRS)

James, Bonnie F.; Norton, O. W. (Compiler); Alexander, Margaret B. (Editor)

1994-01-01

The effects of the natural space environments on spacecraft design, development, and operation are the topic of a series of NASA Reference Publications currently being developed by the Electromagnetics and Environments Branch, Systems Analysis and Integration Laboratory, Marshall Space Flight Center. This primer provides an overview of the natural space environments and their effect on spacecraft design, development, and operations, and also highlights some of the new developments in science and technology for each space environment. It is hoped that a better understanding of the space environment and its effect on spacecraft will enable program management to more effectively minimize program risks and costs, optimize design quality, and successfully achieve mission objectives.

Predicting Material Performance in the Space Environment from Laboratory Test Data, Static Design Environments, and Space Weather Models

NASA Technical Reports Server (NTRS)

Minow, Josep I.; Edwards, David L.

2008-01-01

Qualifying materials for use in the space environment is typically accomplished with laboratory exposures to simulated UV/EUV, atomic oxygen, and charged particle radiation environments with in-situ or subsequent measurements of material properties of interest to the particular application. Choice of environment exposure levels are derived from static design environments intended to represent either mean or extreme conditions that are anticipated to be encountered during a mission. The real space environment however is quite variable. Predictions of the on orbit performance of a material qualified to laboratory environments can be done using information on 'space weather' variations in the real environment. This presentation will first review the variability of space environments of concern for material degradation and then demonstrate techniques for using test data to predict material performance in a variety of space environments from low Earth orbit to interplanetary space using historical measurements and space weather models.

Live births achieved via IVF are increased by improvements in air quality and laboratory environment.

PubMed

Heitmann, Ryan J; Hill, Micah J; James, Aidita N; Schimmel, Tim; Segars, James H; Csokmay, John M; Cohen, Jacques; Payson, Mark D

2015-09-01

Infertility is a common disease, which causes many couples to seek treatment with assisted reproduction techniques. Many factors contribute to successful assisted reproduction technique outcomes. One important factor is laboratory environment and air quality. Our facility had the unique opportunity to compare consecutively used, but separate assisted reproduction technique laboratories, as a result of a required move. Environmental conditions were improved by strategic engineering designs. All other aspects of the IVF laboratory, including equipment, physicians, embryologists, nursing staff and protocols, were kept constant between facilities. Air quality testing showed improved air quality at the new IVF site. Embryo implantation (32.4% versus 24.3%; P < 0.01) and live birth (39.3% versus 31.8%, P < 0.05) were significantly increased in the new facility compared with the old facility. More patients met clinical criteria and underwent mandatory single embryo transfer on day 5 leading to both a reduction in multiple gestation pregnancies and increased numbers of vitrified embryos per patient with supernumerary embryos available. Improvements in IVF laboratory conditions and air quality had profound positive effects on laboratory measures and patient outcomes. This study further strengthens the importance of the laboratory environment and air quality in the success of an IVF programme. Published by Elsevier Ltd.

On the potential for using immersive virtual environments to support laboratory experiment contextualisation

NASA Astrophysics Data System (ADS)

Machet, Tania; Lowe, David; Gütl, Christian

2012-12-01

This paper explores the hypothesis that embedding a laboratory activity into a virtual environment can provide a richer experimental context and hence improve the understanding of the relationship between a theoretical model and the real world, particularly in terms of the model's strengths and weaknesses. While an identified learning objective of laboratories is to support the understanding of the relationship between models and reality, the paper illustrates that this understanding is hindered by inherently limited experiments and that there is scope for improvement. Despite the contextualisation of learning activities having been shown to support learning objectives in many fields, there is traditionally little contextual information presented during laboratory experimentation. The paper argues that the enhancing laboratory activity with contextual information affords an opportunity to improve students' understanding of the relationship between the theoretical model and the experiment (which is effectively a proxy for the complex real world), thereby improving their understanding of the relationship between the model and reality. The authors propose that these improvements can be achieved by setting remote laboratories within context-rich virtual worlds.

Differences in Anticipatory Behaviour between Rats (Rattus norvegicus) Housed in Standard versus Semi-Naturalistic Laboratory Environments.

PubMed

Makowska, I Joanna; Weary, Daniel M

2016-01-01

Laboratory rats are usually kept in relatively small cages, but research has shown that they prefer larger and more complex environments. The physiological, neurological and health effects of standard laboratory housing are well established, but fewer studies have addressed the sustained emotional impact of a standard cage environment. One method of assessing affective states in animals is to look at the animals' anticipatory behaviour between the presentation of a cue signalling the arrival of a reward and the arrival of that reward. The primary aim of this study was to use anticipatory behaviour to assess the affective state experienced by female rats a) reared and housed long-term in a standard laboratory cage versus a semi-naturalistic environment, and b) before and after treatment with an antidepressant or an anxiolytic. A secondary aim was to add to the literature on anticipatory behaviour by describing and comparing the frequency and duration of individual elements of anticipatory behaviour displayed by rats reared in these two systems. In all experiments, total behavioural frequency was higher in standard-housed rats compared to rats from the semi-naturalistic condition, suggesting that standard-housed rats were more sensitive to rewards and experiencing poorer welfare than rats reared in the semi-naturalistic environment. What rats did in anticipation of the reward also differed between housing treatments, with standard-housed rats mostly rearing and rats from the semi-naturalistic condition mostly sitting facing the direction of the upcoming treat. Drug interventions had no effect on the quantity or form of anticipatory behaviour, suggesting that the poorer welfare experienced by standard-housed rats was not analogous to depression or anxiety, or alternatively that the drug interventions were ineffective. This study adds to mounting evidence that standard laboratory housing for rats compromises rat welfare, and provides further scientific support for

Occupational health hazards in the interventional laboratory: time for a safer environment.

PubMed

Klein, Lloyd W; Miller, Donald L; Balter, Stephen; Laskey, Warren; Haines, David; Norbash, Alexander; Mauro, Matthew A; Goldstein, James A

2009-07-01

This document is a consensus statement by the major American societies of physicians who work in the interventional laboratory environment. It reviews available data on the prevalence of occupational health risks and summarizes ongoing epidemiologic studies designed to further elucidate these risks. Its purpose is to affirm that the interventional laboratory poses workplace hazards that must be acknowledged, better understood, and mitigated to the greatest extent possible. Vigorous efforts are advocated to reduce these hazards. Interventional physicians and their professional societies, working together with industry, should strive toward minimizing operator radiation exposure, eliminating the need for personal protective apparel, and ending the orthopedic and ergonomic consequences of the interventional laboratory work environment.

Occupational health hazards in the interventional laboratory: time for a safer environment.

PubMed

Klein, Lloyd W; Miller, Donald L; Balter, Stephen; Laskey, Warren; Haines, David; Norbash, Alexander; Mauro, Matthew A; Goldstein, James A

2009-02-15

This document is a consensus statement by the major American societies of physicians who work in the interventional laboratory environment. It reviews available data on the prevalence of occupational health risks and summarizes ongoing epidemiologic studies designed to further elucidate these risks. Its purpose is to affirm that the interventional laboratory poses workplace hazards that must be acknowledged, better understood, and mitigated to the greatest extent possible. Vigorous efforts are advocated to reduce these hazards. Interventional physicians and their professional societies, working together with industry, should strive toward minimizing operator radiation exposure, eliminating the need for personal protective apparel, and ending the orthopedic and ergonomic consequences of the interventional laboratory work environment. Copyright SIR, 2009

Occupational health hazards in the interventional laboratory: time for a safer environment.

PubMed

Klein, Lloyd W; Miller, Donald L; Balter, Stephen; Laskey, Warren; Haines, David; Norbash, Alexander; Mauro, Matthew A; Goldstein, James A

2009-02-01

This document is a consensus statement by the major American societies of physicians who work in the interventional laboratory environment. It reviews available data on the prevalence of occupational health risks and summarizes ongoing epidemiologic studies designed to further elucidate these risks. Its purpose is to affirm that the interventional laboratory poses workplace hazards that must be acknowledged, better understood, and mitigated to the greatest extent possible. Vigorous efforts are advocated to reduce these hazards. Interventional physicians and their professional societies, working together with industry, should strive toward minimizing operator radiation exposure, eliminating the need for personal protective apparel, and ending the orthopedic and ergonomic consequences of the interventional laboratory work environment.

Choices of Pre-Service Science Teachers Laboratory Environments: Hands-on or Hands-off?

ERIC Educational Resources Information Center

Kapici, Hasan Ozgur; Akcay, Hakan

2018-01-01

Learning in laboratories for students is not only crucial for conceptual understanding, but also contributes to gaining scientific reasoning skills. Following fast developments in technology, online laboratory environments have been improved considerably and nowadays form an attractive alternative for hands-on laboratories. The study was done in…

Examining Student Outcomes in University Computer Laboratory Environments: Issues for Educational Management

ERIC Educational Resources Information Center

Newby, Michael; Marcoulides, Laura D.

2008-01-01

Purpose: The purpose of this paper is to model the relationship between student performance, student attitudes, and computer laboratory environments. Design/methodology/approach: Data were collected from 234 college students enrolled in courses that involved the use of a computer to solve problems and provided the laboratory experience by means of…

MAMMARY GLAND DEVELOPMENT: EARLY LIFE EFFECTS FROM THE ENVIRONMENT

EPA Science Inventory

Mammary Gland Development: Early Life Effects from the Environment

S.E. Fenton. Reproductive Toxicology Division, National Health and Environmental Effects Laboratory, ORD, U.S. EPA, Research Triangle Park, NC 27711.

As signs of precocious puberty in girls reach ...

Circadian phase-shifting effects of a laboratory environment: a clinical trial with bright and dim light.

PubMed

Youngstedt, Shawn D; Kripke, Daniel F; Elliott, Jeffrey A; Rex, Katharine M

2005-09-09

Our aims were to examine the influence of different bright light schedules on mood, sleep, and circadian organization in older adults (n = 60, ages 60-79 years) with insomnia and/or depression, contrasting with responses of young, healthy controls (n = 30, ages 20-40 years). Volunteers were assessed for one week in their home environments. Urine was collected over two 24-hour periods to establish baseline acrophase of 6-sulphatoxymelatonin (aMT6s) excretion. Immediately following home recording, volunteers spent five nights and four days in the laboratory. Sleep periods were fixed at eight hours in darkness, consistent with the volunteers' usual sleep periods. Volunteers were randomly assigned to one of three light treatments (four hours per day) within the wake period: (A) two hours of 3,000 lux at 1-3 hours and 13-15 hours after arising; (B) four hours of 3,000 lux at 6-10 hours after arising; (C) four hours of dim placebo light at 6-10 hours after arising. Lighting was 50 lux during the remainder of wakefulness. The resulting aMT6s acrophase was determined during the final 30 hours in the laboratory. Neither mood nor total melatonin excretion differed significantly by treatment. For the three light treatments, significant and similar phase-response plots were found, indicating that the shift in aMT6s acrophase was dependent upon the circadian time of treatment. The changes in circadian timing were not significantly correlated to changes in sleep or mood. The trial failed to demonstrate photoperiodic effects. The results suggest that even low levels of illumination and/or fixed timing of behavior had significant phase-shifting effects.

Students' Perceptions of a Project-Based Organic Chemistry Laboratory Environment: A Phenomenographic Approach

ERIC Educational Resources Information Center

Burrows, Nikita L.; Nowak, Montana K.; Mooring, Suazette R.

2017-01-01

Students can perceive the laboratory environment in a variety of ways that can affect what they take away from the laboratory course. This qualitative study characterizes undergraduate students' perspectives of a project-based Organic Chemistry laboratory using the theoretical framework of phenomenography. Eighteen participants were interviewed in…

Medical laboratory science and nursing students’ perception of academic learning environment in a Philippine university using Dundee Ready Educational Environment Measure (DREEM)

PubMed Central

2016-01-01

Purpose This study aimed to compare the perception of the academic learning environment between medical laboratory science students and nursing students at Saint Louis University, Baguio City, Philippines. Methods A cross-sectional survey research design was used to measure the perceptions of the participants. A total of 341 students from the Department of Medical Laboratory Science, School of Natural Sciences, and the School of Nursing answered the Dundee Ready Education Environment Measure (DREEM) instrument from April to May 2016. Responses were compared according to course of study, gender, and year level. Results The total mean DREEM scores of the medical laboratory science students and nursing students did not differ significantly when grouped according to course of study, gender, or year level. Medical laboratory science students had significantly lower mean scores in the sub-domains ‘perception of learning’ and ‘perception of teaching.’ Male medical laboratory science students had significantly lower mean scores in the sub-domain ‘perception of learning’ among second year students. Medical laboratory science students had significantly lower mean scores in the sub-domain ‘perception of learning.’ Nursing students identified 7 problem areas, most of which were related to their instructors. Conclusion Medical laboratory science and nursing students viewed their academic learning environment as ‘more positive than negative.’ However, the relationship of the nursing instructors to their students needs improvement. PMID:27649901

Medical laboratory science and nursing students' perception of academic learning environment in a Philippine university using Dundee Ready Educational Environment Measure (DREEM).

PubMed

Barcelo, Jonathan M

2016-01-01

This study aimed to compare the perception of the academic learning environment between medical laboratory science students and nursing students at Saint Louis University, Baguio City, Philippines. A cross-sectional survey research design was used to measure the perceptions of the participants. A total of 341 students from the Department of Medical Laboratory Science, School of Natural Sciences, and the School of Nursing answered the Dundee Ready Education Environment Measure (DREEM) instrument from April to May 2016. Responses were compared according to course of study, gender, and year level. The total mean DREEM scores of the medical laboratory science students and nursing students did not differ significantly when grouped according to course of study, gender, or year level. Medical laboratory science students had significantly lower mean scores in the sub-domains 'perception of learning' and 'perception of teaching.' Male medical laboratory science students had significantly lower mean scores in the sub-domain 'perception of learning' among second year students. Medical laboratory science students had significantly lower mean scores in the sub-domain 'perception of learning.' Nursing students identified 7 problem areas, most of which were related to their instructors. Medical laboratory science and nursing students viewed their academic learning environment as 'more positive than negative.' However, the relationship of the nursing instructors to their students needs improvement.

Development and Cross-National Validation of a Laboratory Classroom Environment Instrument for Senior High School Science.

ERIC Educational Resources Information Center

Fraser, Barry J.; And Others

1993-01-01

Describes the development of the Science Laboratory Environment Inventory (SLEI) instrument for assessing perceptions of the psychosocial environment in science laboratory classrooms, and reports validation information for samples of senior high school students from six different countries. The SLEI assesses five dimensions of the actual and…

Instructional designing the STEM education model for fostering creative thinking abilities in physics laboratory environment classes

NASA Astrophysics Data System (ADS)

Chanthala, Chumpon; Santiboon, Toansakul; Ponkham, Kamon

2018-01-01

To investigate the effects of students' activity-based on learning approaching management through the STEM Education Instructional Model for fostering their creative thinking abilities of their learning achievements in physics laboratory classroom environments with the sample size consisted of 48 students at the 10th grade level in two classes in Mahasarakham University Demonstration School(Secondary Division) in Thailand. Students' creative thinking abilities were assessed with the with the 24-item GuilfordCreative Thinking Questionnaire (GCTQ). Students' perceptions of their physics classroom learning environments were obtained using the 35-item Physics Laboratory Environment Inventory (PLEI). Associations between students' learning achievements of their post-test assessment indicated that 26% of the coefficient predictive value (R2) of the variance in students' creative thinking abilities was attributable to their perceptions for the GCTQ. Students' learning outcomes of their post-test assessment, the R2value indicated that 35% of the variances for the PLEI, the R2value indicated that 63% of the variances for their creative thinking abilities were attributable to theiraffecting the activity-based on learning for fostering their creative thinking are provided.

Development of an Instrument for Assessing Senior High School Students' Preferred and Perceived Laboratory Classroom Environment

ERIC Educational Resources Information Center

Hsiao, Chien-Hua; Wu, Ying-Tien; Lin, Chung-Yen; Wong, Terrence William; Fu, Hsieh-Hai; Yeh, Ting-Kuang; Chang, Chung-Yen

2014-01-01

This study aimed to develop an instrument, named the inquiry-based laboratory classroom environment instrument (ILEI), for assessing senior high-school science students' preferred and perceived laboratory environment. A total of 262 second-year students, from a senior-high school in Taiwan, were recruited for this study. Four stages were included…

The Interest of the Diversity of Perspectives and Methodologies in Evaluating the Science Laboratory Learning Environment

ERIC Educational Resources Information Center

Membiela, Pedro; Vidal, Manuel

2017-01-01

The importance of researching the opinions of students and teachers has been pointed out concerning the improvement of teaching and learning in laboratory environments. In this regard, a study of the laboratory environment was carried out from a diversity of perspectives and methodologies. By means of a questionnaire it was learned that the…

Pharmaceutical process chemistry: evolution of a contemporary data-rich laboratory environment.

PubMed

Caron, Stéphane; Thomson, Nicholas M

2015-03-20

Over the past 20 years, the industrial laboratory environment has gone through a major transformation in the industrial process chemistry setting. In order to discover and develop robust and efficient syntheses and processes for a pharmaceutical portfolio with growing synthetic complexity and increased regulatory expectations, the round-bottom flask and other conventional equipment familiar to a traditional organic chemistry laboratory are being replaced. The new process chemistry laboratory fosters multidisciplinary collaborations by providing a suite of tools capable of delivering deeper process understanding through mechanistic insights and detailed kinetics translating to greater predictability at scale. This transformation is essential to the field of organic synthesis in order to promote excellence in quality, safety, speed, and cost efficiency in synthesis.

Laboratory investigations: Low Earth orbit environment chemistry with spacecraft surfaces

NASA Technical Reports Server (NTRS)

Cross, Jon B.

1990-01-01

Long-term space operations that require exposure of material to the low earth orbit (LEO) environment must take into account the effects of this highly oxidative atmosphere on material properties and the possible contamination of the spacecraft surroundings. Ground-based laboratory experiments at Los Alamos using a newly developed hyperthermal atomic oxygen (AO) source have shown that not only are hydrocarbon based materials effected but that inorganic materials such as MoS2 are also oxidized and that thin protective coatings such as Al2O3 can be breached, producing oxidation of the underlying substrate material. Gas-phase reaction products, such as SO2 from oxidation of MoS2 and CO and CO2 from hydrocarbon materials, have been detected and have consequences in terms of spacecraft contamination. Energy loss through gas-surface collisions causing spacecraft drag has been measured for a few select surfaces and has been found to be highly dependent on the surface reactivity.

Assessing Student Learning in a Virtual Laboratory Environment

ERIC Educational Resources Information Center

Wolf, T.

2010-01-01

Laboratory experience is a key factor in technical and scientific education. Virtual laboratories have been proposed to reduce cost and simplify maintenance of lab facilities while still providing students with access to real systems. It is important to determine if such virtual labs are still effective for student learning. In the assessment of a…

Adaptation of Drosophila to a novel laboratory environment reveals temporally heterogeneous trajectories of selected alleles.

PubMed

Orozco-terWengel, Pablo; Kapun, Martin; Nolte, Viola; Kofler, Robert; Flatt, Thomas; Schlötterer, Christian

2012-10-01

The genomic basis of adaptation to novel environments is a fundamental problem in evolutionary biology that has gained additional importance in the light of the recent global change discussion. Here, we combined laboratory natural selection (experimental evolution) in Drosophila melanogaster with genome-wide next generation sequencing of DNA pools (Pool-Seq) to identify alleles that are favourable in a novel laboratory environment and traced their trajectories during the adaptive process. Already after 15 generations, we identified a pronounced genomic response to selection, with almost 5000 single nucleotide polymorphisms (SNP; genome-wide false discovery rates < 0.005%) deviating from neutral expectation. Importantly, the evolutionary trajectories of the selected alleles were heterogeneous, with the alleles falling into two distinct classes: (i) alleles that continuously rise in frequency; and (ii) alleles that at first increase rapidly but whose frequencies then reach a plateau. Our data thus suggest that the genomic response to selection can involve a large number of selected SNPs that show unexpectedly complex evolutionary trajectories, possibly due to nonadditive effects. © 2012 Blackwell Publishing Ltd.

Student Perceptions of Chemistry Laboratory Learning Environments, Student-Teacher Interactions and Attitudes in Secondary School Gifted Education Classes in Singapore

NASA Astrophysics Data System (ADS)

Lang, Quek Choon; Wong, Angela F. L.; Fraser, Barry J.

2005-09-01

This study investigated the chemistry laboratory classroom environment, teacher-student interactions and student attitudes towards chemistry among 497 gifted and non-gifted secondary-school students in Singapore. The data were collected using the 35-item Chemistry Laboratory Environment Inventory (CLEI), the 48-item Questionnaire on Teacher Interaction (QTI) and the 30-item Questionnaire on Chemistry-Related Attitudes (QOCRA). Results supported the validity and reliability of the CLEI and QTI for this sample. Stream (gifted versus non-gifted) and gender differences were found in actual and preferred chemistry laboratory classroom environments and teacher-student interactions. Some statistically significant associations of modest magnitude were found between students' attitudes towards chemistry and both the laboratory classroom environment and the interpersonal behaviour of chemistry teachers. Suggestions for improving chemistry laboratory classroom environments and the teacher-student interactions for gifted students are provided.

The viability of establishing collaborative, reconfigurable research environments for the Human Performance Research Laboratory at NASA Ames

NASA Technical Reports Server (NTRS)

Clipson, Colin

1994-01-01

This paper will review and summarize research initiatives conducted between 1987 and 1992 at NASA Ames Research Center by a research team from the University of Michigan Architecture Research Laboratory. These research initiatives, funded by a NASA grant NAG2-635, examined the viability of establishing collaborative, reconfigurable research environments for the Human Performance Research Laboratory at NASA Ames in California. Collaborative Research Environments are envisioned as a way of enhancing the work of NASA research teams, optimizing the use of shared resources, and providing superior environments for housing research activities. The Integrated Simulation Project at NASA, Ames Human Performance Research Laboratory is one of the current realizations of this initiative.

Measurement Tools for the Immersive Visualization Environment: Steps Toward the Virtual Laboratory.

PubMed

Hagedorn, John G; Dunkers, Joy P; Satterfield, Steven G; Peskin, Adele P; Kelso, John T; Terrill, Judith E

2007-01-01

This paper describes a set of tools for performing measurements of objects in a virtual reality based immersive visualization environment. These tools enable the use of the immersive environment as an instrument for extracting quantitative information from data representations that hitherto had be used solely for qualitative examination. We provide, within the virtual environment, ways for the user to analyze and interact with the quantitative data generated. We describe results generated by these methods to obtain dimensional descriptors of tissue engineered medical products. We regard this toolbox as our first step in the implementation of a virtual measurement laboratory within an immersive visualization environment.

Exposure to hazardous substances in a standard molecular biology laboratory environment: evaluation of exposures in IARC laboratories.

PubMed

Chapot, Brigitte; Secretan, Béatrice; Robert, Annie; Hainaut, Pierre

2009-07-01

Working in a molecular biology laboratory environment implies regular exposure to a wide range of hazardous substances. Several recent studies have shown that laboratory workers may have an elevated risk of certain cancers. Data on the nature and frequency of exposures in such settings are scanty. The frequency of use of 163 agents by staff working in molecular biology laboratories was evaluated over a period of 4 years by self-administered questionnaire. Of the agents listed, ethanol was used by the largest proportion of staff (70%), followed by ethidium bromide (55%). Individual patterns of use showed three patterns, namely (i) frequent use of a narrow range of products, (ii) occasional use of a wide range of products, and (iii) frequent and occasional use of an intermediate range of products. Among known or suspected carcinogens (International Agency for Research on Cancer Group 1 and 2A, respectively), those most frequently used included formaldehyde (17%), oncogenic viruses (4%), and acrylamide (32%). The type of exposure encountered in research laboratories is extremely diverse. Few carcinogenic agents are used frequently but many laboratory workers may be exposed occasionally to known human carcinogens. In addition, many of the chemicals handled by staff represent a health hazard. The results enabled the staff physician to develop an individual approach to medical surveillance and to draw a personal history of occupational exposures for laboratory staff.

Web Environment for Programming and Control of a Mobile Robot in a Remote Laboratory

ERIC Educational Resources Information Center

dos Santos Lopes, Maísa Soares; Gomes, Iago Pacheco; Trindade, Roque M. P.; da Silva, Alzira F.; de C. Lima, Antonio C.

2017-01-01

Remote robotics laboratories have been successfully used for engineering education. However, few of them use mobile robots to to teach computer science. This article describes a mobile robot Control and Programming Environment (CPE) and its pedagogical applications. The system comprises a remote laboratory for robotics, an online programming tool,…

Aerothermodynamic Environments Definition for the Mars Science Laboratory Entry Capsule

NASA Technical Reports Server (NTRS)

Edquist, Karl T.; Dyakonov, Artem A.; Wright, Michael J.; Tang, Chun Y.

2007-01-01

An overview of the aerothermodynamic environments definition status is presented for the Mars Science Laboratory entry vehicle. The environments are based on Navier-Stokes flowfield simulations on a candidate aeroshell geometry and worst-case entry heating trajectories. Uncertainties for the flowfield predictions are based primarily on available ground data since Mars flight data are scarce. The forebody aerothermodynamics analysis focuses on boundary layer transition and turbulent heating augmentation. Turbulent transition is expected prior to peak heating, a first for Mars entry, resulting in augmented heat flux and shear stress at the same heatshield location. Afterbody computations are also shown with and without interference effects of reaction control system thruster plumes. Including uncertainties, analysis predicts that the heatshield may experience peaks of 225 W/sq cm for turbulent heat flux, 0.32 atm for stagnation pressure, and 400 Pa for turbulent shear stress. The afterbody heat flux without thruster plume interference is predicted to be 7 W/sq cm on the backshell and 10 W/sq cm on the parachute cover. If the reaction control jets are fired near peak dynamic pressure, the heat flux at localized areas could reach as high as 76 W/sq cm on the backshell and 38 W/sq cm on the parachute cover, including uncertainties. The final flight environments used for hardware design will be updated for any changes in the aeroshell configuration, heating design trajectories, or uncertainties.

Occupational health hazards in the interventional laboratory: Time for a safer environment.

PubMed

Klein, Lloyd W; Miller, Donald L; Balter, Stephen; Laskey, Warren; Naito, Neil; Haines, David; Ross, Allan; Mauro, Matthew A; Goldstein, James A

2018-01-04

Over the past 30 years, the advent of fluoroscopically guided interventional procedures has resulted in dramatic increments in both X-ray exposure and physical demands that predispose interventionists to distinct occupational health hazards. The hazards of accumulated radiation exposure have been known for years, but until recently the other potential risks have been ill-defined and under-appreciated. The physical stresses inherent in this career choice appear to be associated with a predilection to orthopedic injuries, attributable in great part to the cumulative adverse effects of bearing the weight and design of personal protective apparel worn to reduce radiation risk and to the poor ergonomic design of interventional suites. These occupational health concerns pertain to cardiologists, radiologists and surgeons working with fluoroscopy, pain management specialists performing nonvascular fluoroscopic procedures, and the many support personnel working in these environments. This position paper is the work of representatives of the major societies of physicians who work in the interventional laboratory environment, and has been formally endorsed by all. In this paper, the available data delineating the prevalence of these occupational health risks is reviewed and ongoing epidemiological studies designed to further elucidate these risks are summarized. The main purpose is to publicly state speaking with a single voice that the interventional laboratory poses workplace hazards that must be acknowledged, better understood and mitigated to the greatest extent possible, and to advocate vigorously on behalf of efforts to reduce these hazards. Interventional physicians and their professional societies, working together with industry, should strive toward the ultimate zero radiation exposure work environment that would eliminate the need for personal protective apparel and prevent its orthopedic and ergonomic consequences. © 2008 Wiley-Liss, Inc. Copyright © 2008 Wiley�

Effective utilization of clinical laboratories.

PubMed

Murphy, J; Henry, J B

1978-11-01

Effective utilization of clinical laboratories requires that underutilization, overutilization, and malutilization be appreciated and eliminated or reduced. Optimal patient care service, although subjective to a major extent, is reflected in terms of outcome and cost. Increased per diem charges, reduced hospital stay, and increased laboratory workload over the past decade all require each laboratory to examine its internal operations to achieve economy and efficiency as well as maximal effectiveness. Increased research and development, an active managerial role on the part of pathologists, internal self-assessment, and an aggressive response to sophisticated scientific and clinical laboratory data base requirements are not only desirable but essential. The importance of undergraduate and graduate medical education in laboratory medicine to insure understanding as well as effective utilization is stressed. The costs and limitations as well as the accuracy, precision, sensitivity, specificity, and pitfalls of measurements and examinations must also be fully appreciated. Medical malpractice and defensive medicine and the use of critical values, emergency and routine services, and an active clinical role by the pathologist are of the utmost value in assuring effective utilization of the laboratory. A model for the optimal use of the laboratory including economy and efficiency has been achieved in the blood bank in regard to optimal hemotherapy for elective surgery, assuring superior patient care in a cost effective and safe manner.

Utica Shale Energy and Environment Laboratory (USEEL)

NASA Astrophysics Data System (ADS)

Cole, D. R.

2017-12-01

Despite the rapid growth of the UOG industry in the Appalachian Basin of Pennsylvania and neighboring states, there are still fundamental concerns regarding the environmentally sound and cost efficient extraction of this unique asset. To address these concerns, Ohio State University has established the Department of Energy-funded Utica Shale Energy and Environment Laboratory, a dedicated research program where scientists from the university will work with the U.S. Department of Energy (DOE) National Energy Technology Laboratory (NETL), academia, industry, and regulatory partners, to measure and monitor reservoir response to UOG development and any associated environmental concerns. The USEEL site will be located in Greene County, Pennsylvania, in the heart of the deep Utica-Pt. Pleasant Shale play of the Appalachian Basin. The USEEL project team will characterize and quantify the gas-producing attributes of one of the deepest portions of the Utica-Pt. Pleasant formations in the Appalachian Basin via a multi-disciplinary collaboration that leverages state-of-the-art capabilities in geochemistry, core assessment, well design and logging, 3-D and micro-seismic, DTS and DAS fiber optics, and reservoir modelling. Fracture and rock strength analyses will be complemented by a comprehensive suite of geophysical and geochemical logs, water and chip samples, and cores (pressure sidewall and whole core) to evaluate fluids, mineral alteration, microbes, pore structure, and hydrocarbon formation and alteration in the shale pore space. Located on an existing Marcellus drill pads in southwestern Pennsylvania, USEEL will provide an unprecedented opportunity to evaluate the economic and environmental effects of Marcellus pad expansion on the integrity of near-by existing production wells, ground disruption and slope stability, and ultimate efforts to conduct site reclamation. Combined with the overall goal of an improved understanding of the Utica-Pt. Pleasant system, USEEL

Physical and Psychosocial Aspects of the Learning Environment in the Science Laboratory and Their Relationship to Teacher Satisfaction

ERIC Educational Resources Information Center

Che Ahmad, Che Nidzam; Osman, Kamisah; Halim, Lilia

2013-01-01

This paper is a report of a survey conducted to determine teachers' perception of the science laboratory learning environment and the relationship between different aspects of this environment and satisfaction from teaching and learning. Teachers' perceptions of psychosocial aspects were measured by use of the Science Laboratory Environment…

Microgravity Effects on Microbiology In Space Laboratories

NASA Technical Reports Server (NTRS)

Nelson, Emily S.; Juergensmeyer, Elizabeth; Juergensmeyer, Margaret

2000-01-01

Here we present a review of the effects of residual acceleration on microorganisms in space Laboratories. Residual acceleration in the microgravity environment is frequently ignored by microbiologists, although their experiments may be as sensitive to this acceleration as those designed by materials scientists and fluid physicists. Furthermore, analysis to date has been largely empirical and/or based on very simple theoretical models. As a result, the responses of single cells to the space environment are widely assumed to be taking place in "pure" microgravity. These responses vary widely and are not well understood. Some of this variation may be due to the range of microgravity conditions experience by organisms. In the future, as we move from visiting orbital environments to living and working there, we will undoubtedly bring microorganisms with us. It is also quite likely that the first extraterrestrial life we encounter will be single-celled organisms. Therefore, we would like to present a summary of the current knowledge base, and to challenge the space community to develop new approaches in understanding this important field.

[Implementation of "5S" methodology in laboratory safety and its effect on employee satisfaction].

PubMed

Dogan, Yavuz; Ozkutuk, Aydan; Dogan, Ozlem

2014-04-01

Health institutions use the accreditation process to achieve improvement across the organization and management of the health care system. An ISO 15189 quality and efficiency standard is the recommended standard for medical laboratories qualification. The "safety and accommodation conditions" of this standard covers the requirement to improve working conditions and maintain the necessary safety precautions. The most inevitable precaution for ensuring a safe environment is the creation of a clean and orderly environment to maintain a potentially safe surroundings. In this context, the 5S application which is a superior improvement tool that has been used by the industry, includes some advantages such as encouraging employees to participate in and to help increase the productivity. The main target of this study was to implement 5S methods in a clinical laboratory of a university hospital for evaluating its effect on employees' satisfaction, and correction of non-compliance in terms of the working environment. To start with, first, 5S education was given to management and employees. Secondly, a 5S team was formed and then the main steps of 5S (Seiri: Sort, Seiton: Set in order, Seiso: Shine, Seiketsu: Standardize, and Shitsuke: Systematize) were implemented for a duration of 3 months. A five-point likert scale questionnaire was used in order to determine and assess the impact of 5S on employees' satisfaction considering the areas such as facilitating the job, the job satisfaction, setting up a safe environment, and the effect of participation in management. Questionnaire form was given to 114 employees who actively worked during the 5S implementation period, and the data obtained from 63 (52.3%) participants (16 male, 47 female) were evaluated. The reliability of the questionnaire's Cronbach's alpha value was determined as 0.858 (p< 0.001). After the implementation of 5S it was observed and determined that facilitating the job and setting up a safe environment created

Low-gravity Orbiting Research Laboratory Environment Potential Impact on Space Biology Research

NASA Technical Reports Server (NTRS)

Jules, Kenol

2006-01-01

One of the major objectives of any orbital space research platform is to provide a quiescent low gravity, preferably a zero gravity environment, to perform fundamental as well as applied research. However, small disturbances exist onboard any low earth orbital research platform. The impact of these disturbances must be taken into account by space research scientists during their research planning, design and data analysis in order to avoid confounding factors in their science results. The reduced gravity environment of an orbiting research platform in low earth orbit is a complex phenomenon. Many factors, among others, such as experiment operations, equipment operation, life support systems and crew activity (if it is a crewed platform), aerodynamic drag, gravity gradient, rotational effects as well as the vehicle structural resonance frequencies (structural modes) contribute to form the overall reduced gravity environment in which space research is performed. The contribution of these small disturbances or accelerations is precisely why the environment is NOT a zero gravity environment, but a reduced acceleration environment. This paper does not discuss other factors such as radiation, electromagnetic interference, thermal and pressure gradient changes, acoustic and CO2 build-up to name a few that affect the space research environment as well, but it focuses solely on the magnitude of the acceleration level found on orbiting research laboratory used by research scientists to conduct space research. For ease of analysis this paper divides the frequency spectrum relevant to most of the space research disciplines into three regimes: a) quasi-steady, b) vibratory and c) transient. The International Space Station is used as an example to illustrate the point. The paper discusses the impact of these three regimes on space biology research and results from space flown experiments are used to illustrate the potential negative impact of these disturbances (accelerations

Microgravity Environment Description Handbook

NASA Technical Reports Server (NTRS)

DeLombard, Richard; McPherson, Kevin; Hrovat, Kenneth; Moskowitz, Milton; Rogers, Melissa J. B.; Reckart, Timothy

1997-01-01

The Microgravity Measurement and Analysis Project (MMAP) at the NASA Lewis Research Center (LeRC) manages the Space Acceleration Measurement System (SAMS) and the Orbital Acceleration Research Experiment (OARE) instruments to measure the microgravity environment on orbiting space laboratories. These laboratories include the Spacelab payloads on the shuttle, the SPACEHAB module on the shuttle, the middeck area of the shuttle, and Russia's Mir space station. Experiments are performed in these laboratories to investigate scientific principles in the near-absence of gravity. The microgravity environment desired for most experiments would have zero acceleration across all frequency bands or a true weightless condition. This is not possible due to the nature of spaceflight where there are numerous factors which introduce accelerations to the environment. This handbook presents an overview of the major microgravity environment disturbances of these laboratories. These disturbances are characterized by their source (where known), their magnitude, frequency and duration, and their effect on the microgravity environment. Each disturbance is characterized on a single page for ease in understanding the effect of a particular disturbance. The handbook also contains a brief description of each laboratory.

The response of the tidepool sculpin, Oligocottus maculosus, to hypoxia in laboratory, mesocosm and field environments.

PubMed

Sloman, Katherine A; Mandic, Milica; Todgham, Anne E; Fangue, Nann A; Subrt, Peter; Richards, Jeffrey G

2008-03-01

Animals living in the intertidal zone experience regular, predictable fluctuations in physical parameters including temperature, oxygen and salinity and rely on behavioural, physiological and biochemical mechanisms to cope with environmental variation. In the present study, behavioural strategies induced by aquatic hypoxia (e.g. emergence) were performed at similar oxygen tensions across laboratory, mesocosm and field environments; the number of individuals performing these behaviours at any one time was similar in mesocosms and the field. The use of aquatic surface respiration (ASR) was more plastic than emergence behaviour, occurring at a lower oxygen tension in juveniles than adults and being influenced by the addition of alarm substance. Oxygen uptake was lower in air than in water in adults but, in contrast, oxygen uptake was not influenced by the respiratory medium in juveniles. In the laboratory, 72 h of forced emergence did not affect whole body concentrations of lactate but when ASR and emergence were prevented within mesocosm environments there was a significant elevation of lactate. The present study highlights the benefits of transcending traditional laboratory/field boundaries allowing the responses of laboratory-held animals to environmental fluctuation to be integrated with how these animals perform in their natural environment.

Virtual Chemistry Laboratory: Effect of Constructivist Learning Environment

ERIC Educational Resources Information Center

Tatli, Zeynep; Ayas, Alipasa

2012-01-01

The lab applications, which were started to be applied through mid 19th century, not only provide a new point of view but also bring about a new dimension to the lessons. At early times they were used to prove theoretical knowledge but lately they turned into environments where students freely discover knowledge as an individual or in groups. The…

Multi-modal virtual environment research at Armstrong Laboratory

NASA Technical Reports Server (NTRS)

Eggleston, Robert G.

1995-01-01

One mission of the Paul M. Fitts Human Engineering Division of Armstrong Laboratory is to improve the user interface for complex systems through user-centered exploratory development and research activities. In support of this goal, many current projects attempt to advance and exploit user-interface concepts made possible by virtual reality (VR) technologies. Virtual environments may be used as a general purpose interface medium, an alternative display/control method, a data visualization and analysis tool, or a graphically based performance assessment tool. An overview is given of research projects within the division on prototype interface hardware/software development, integrated interface concept development, interface design and evaluation tool development, and user and mission performance evaluation tool development.

Characterizing Instructional Practices in the Laboratory: The Laboratory Observation Protocol for Undergraduate STEM

ERIC Educational Resources Information Center

Velasco, Jonathan B.; Knedeisen, Adam; Xue, Dihua; Vickrey, Trisha L.; Abebe, Marytza; Stains, Marilyne

2016-01-01

Chemistry laboratories play an essential role in the education of undergraduate Science, Technology, Engineering, and Mathematics (STEM) and non-STEM students. The extent of student learning in any educational environment depends largely on the effectiveness of the instructors. In chemistry laboratories at large universities, the instructors of…

Laboratory Control System's Effects on Student Achievement and Attitudes

ERIC Educational Resources Information Center

Cicek, Fatma Gozalan; Taspinar, Mehmet

2016-01-01

Problem Statement: The current study investigates whether the learning environment designed based on the laboratory control system affects the academic achievement, the attitude toward the learning-teaching process and the retention of the students in computer education. Purpose of Study: The study aims to identify the laboratory control system…

Learning Environment, Attitudes and Achievement among Middle-School Science Students Using Inquiry-Based Laboratory Activities

ERIC Educational Resources Information Center

Wolf, Stephen J.; Fraser, Barry J.

2008-01-01

This study compared inquiry and non-inquiry laboratory teaching in terms of students' perceptions of the classroom learning environment, attitudes toward science, and achievement among middle-school physical science students. Learning environment and attitude scales were found to be valid and related to each other for a sample of 1,434 students in…

Mars' surface radiation environment measured with the Mars Science Laboratory's Curiosity rover.

PubMed

Hassler, Donald M; Zeitlin, Cary; Wimmer-Schweingruber, Robert F; Ehresmann, Bent; Rafkin, Scot; Eigenbrode, Jennifer L; Brinza, David E; Weigle, Gerald; Böttcher, Stephan; Böhm, Eckart; Burmeister, Soenke; Guo, Jingnan; Köhler, Jan; Martin, Cesar; Reitz, Guenther; Cucinotta, Francis A; Kim, Myung-Hee; Grinspoon, David; Bullock, Mark A; Posner, Arik; Gómez-Elvira, Javier; Vasavada, Ashwin; Grotzinger, John P

2014-01-24

The Radiation Assessment Detector (RAD) on the Mars Science Laboratory's Curiosity rover began making detailed measurements of the cosmic ray and energetic particle radiation environment on the surface of Mars on 7 August 2012. We report and discuss measurements of the absorbed dose and dose equivalent from galactic cosmic rays and solar energetic particles on the martian surface for ~300 days of observations during the current solar maximum. These measurements provide insight into the radiation hazards associated with a human mission to the surface of Mars and provide an anchor point with which to model the subsurface radiation environment, with implications for microbial survival times of any possible extant or past life, as well as for the preservation of potential organic biosignatures of the ancient martian environment.

Report: Results of Technical Network Vulnerability Assessment: EPA’s Radiation and Indoor Environments National Laboratory

EPA Pesticide Factsheets

Report #09-P-0053, December 9, 2008. Vulnerability testing of EPA’s Radiation and Indoor Environments National Laboratory (R&IEN) network identified Internet Protocol addresses with medium-risk vulnerabilities.

Students' Understanding and Perceptions of Assigned Team Roles in a Classroom Laboratory Environment

PubMed Central

Ott, Laura E.; Kephart, Kerrie; Stolle-McAllister, Kathleen; LaCourse, William R.

2018-01-01

Using a cooperative learning framework in a quantitative reasoning laboratory course, students were assigned to static teams of four in which they adopted roles that rotated regularly. The roles included: team leader, protocol manager, data recorder, and researcher. Using a mixed-methods approach, we investigated students' perceptions of the team roles and specifically addressed students' understanding of the roles, students' beliefs in their ability to enact the roles, and whether working with assigned team roles supported the teams to work effectively and cohesively. Although students expressed confidence in their understanding of the team roles, their understanding differed from the initial descriptions. This suggests that students' understanding of team roles may be influenced by a variety of factors, including their experiences within their teams. Students also reported that some roles appeared to lack a purpose, implying that for roles to be successful, they must have a clear purpose. Finally, the fact that many students reported ignoring the team roles suggests that students do not perceive roles as a requirement for team productivity and cohesion. On the basis of these findings, we provide recommendations for instructors wishing to establish a classroom group laboratory environment. PMID:29681667

Development of Wave Turbine Emulator in a Laboratory Environment

NASA Astrophysics Data System (ADS)

Vinatha, U.; Vittal K, P.

2013-07-01

Wave turbine emulator (WTE) is an important equipment for developing wave energy conversion system. The emulator reflects the actual behavior of the wave turbine by reproducing the characteristics of real wave turbine without reliance on natural wave resources and actual wave turbine. It offers a controllable test environment that allows the evaluation and improvement of control schemes for electric generators. The emulator can be used for research applications to drive an electrical generator in a similar way as a practical wave turbine. This article presents the development of a WTE in a laboratory environment and studies on the behavior of electrical generator coupled to the emulator. The structure of a WTE consists of a PC where the characteristics of the turbine are implemented, ac drive to emulate the turbine rotor, feedback mechanism from the drive and power electronic equipment to control the drive. The feedback signal is acquired by the PC through an A/D converter, and the signal for driving the power electronic device comes from the PC through a D/A converter.

A monitor for the laboratory evaluation of control integrity in digital control systems operating in harsh electromagnetic environments

NASA Technical Reports Server (NTRS)

Belcastro, Celeste M.; Fischl, Robert; Kam, Moshe

1992-01-01

This paper presents a strategy for dynamically monitoring digital controllers in the laboratory for susceptibility to electromagnetic disturbances that compromise control integrity. The integrity of digital control systems operating in harsh electromagnetic environments can be compromised by upsets caused by induced transient electrical signals. Digital system upset is a functional error mode that involves no component damage, can occur simultaneously in all channels of a redundant control computer, and is software dependent. The motivation for this work is the need to develop tools and techniques that can be used in the laboratory to validate and/or certify critical aircraft controllers operating in electromagnetically adverse environments that result from lightning, high-intensity radiated fields (HIRF), and nuclear electromagnetic pulses (NEMP). The detection strategy presented in this paper provides dynamic monitoring of a given control computer for degraded functional integrity resulting from redundancy management errors, control calculation errors, and control correctness/effectiveness errors. In particular, this paper discusses the use of Kalman filtering, data fusion, and statistical decision theory in monitoring a given digital controller for control calculation errors.

Investigating Student Perceptions of the Chemistry Laboratory and Their Approaches to Learning in the Laboratory

NASA Astrophysics Data System (ADS)

Berger, Spencer Granett

This dissertation explores student perceptions of the instructional chemistry laboratory and the approaches students take when learning in the laboratory environment. To measure student perceptions of the chemistry laboratory, a survey instrument was developed. 413 students responded to the survey during the Fall 2011 semester. Students' perception of the usefulness of the laboratory in helping them learn chemistry in high school was related to several factors regarding their experiences in high school chemistry. Students' perception of the usefulness of the laboratory in helping them learn chemistry in college was also measured. Reasons students provided for the usefulness of the laboratory were categorized. To characterize approaches to learning in the laboratory, students were interviewed midway through semester (N=18). The interviews were used to create a framework describing learning approaches that students use in the laboratory environment. Students were categorized into three levels: students who view the laboratory as a requirement, students who believe that the laboratory augments their understanding, and students who view the laboratory as an important part of science. These categories describe the types of strategies students used when conducting experiments. To further explore the relationship between students' perception of the laboratory and their approaches to learning, two case studies are described. These case studies involve interviews in the beginning and end of the semester. In the interviews, students reflect on what they have learned in the laboratory and describe their perceptions of the laboratory environment. In order to encourage students to adopt higher-level approaches to learning in the laboratory, a metacognitive intervention was created. The intervention involved supplementary questions that students would answer while completing laboratory experiments. The questions were designed to encourage students to think critically about the

Light field and water clarity simulation of natural environments in laboratory conditions

NASA Astrophysics Data System (ADS)

Pe'eri, Shachak; Shwaery, Glenn

2012-06-01

Simulation of natural oceanic conditions in a laboratory setting is a challenging task, especially when that environment can be miles away. We present an attempt to replicate the solar radiation expected at different latitudes with varying water clarity conditions up to 30 m in depth using a 2.5 m deep engineering tank at the University of New Hampshire. The goals of the study were: 1) to configure an underwater light source that produced an irradiance spectrum similar to natural daylight with the sun at zenith and at 60° under clear atmospheric conditions, and 2) to monitor water clarity as a function of depth. Irradiance was measured using a spectra-radiometer with a cosine receiver to analyze the output spectrum of submersed lamps as a function of distance. In addition, an underwater reflection method was developed to measure the diffuse attenuation coefficient in real time. Two water clarity types were characterized, clear waters representing deep, open-ocean conditions, and murky waters representing littoral environments. Results showed good correlation between the irradiance measured at 400 nm to 600 nm and the natural daylight spectrum at 3 m from the light source. This can be considered the water surface conditions reference. Using these methodologies in a controlled laboratory setting, we are able to replicate illumination and water conditions to study the physical, chemical and biological processes on natural and man-made objects and/or systems in simulated, varied geographic locations and environments.

Development of a prediction model on the acceptance of electronic laboratory notebooks in academic environments.

PubMed

Kloeckner, Frederik; Farkas, Robert; Franken, Tobias; Schmitz-Rode, Thomas

2014-04-01

Documentation of research data plays a key role in the biomedical engineering innovation processes. It makes an important contribution to the protection of intellectual property, the traceability of results and fulfilling the regulatory requirement. Because of the increasing digitalization in laboratories, an electronic alternative to the commonly-used paper-bound notebooks could contribute to the production of sophisticated documentation. However, compared to in an industrial environment, the use of electronic laboratory notebooks is not widespread in academic laboratories. Little is known about the acceptance of an electronic documentation system and the underlying reasons for this. Thus, this paper aims to establish a prediction model on the potential preference and acceptance of scientists either for paper-based or electronic documentation. The underlying data for the analysis originate from an online survey of 101 scientists in industrial, academic and clinical environments. Various parameters were analyzed to identify crucial factors for the system preference using binary logistic regression. The analysis showed significant dependency between the documentation system preference and the supposed workload associated with the documentation system (p<0.006; odds ratio=58.543) and an additional personal component. Because of the dependency of system choice on specific parameters it is possible to predict the acceptance of an electronic laboratory notebook before implementation.

Evolution and validation of a personal form of an instrument for assessing science laboratory classroom environments

NASA Astrophysics Data System (ADS)

Fraser, Barry J.; Giddings, Geoffrey J.; McRobbie, Campbell J.

The research reported in this article makes two distinctive contributions to the field of classroom environment research. First, because existing instruments are unsuitable for science laboratory classes, the Science Laboratory Environment Inventory (SLEI) was developed and validated. Second, a new Personal form of the SLEI (involving a student's perceptions of his or her own role within the class) was developed and validated in conjunction with the conventional Class form (involving a student's perceptions of the class as a whole), and its usefulness was investigated. The instrument was cross-nationally fieldtested with 5,447 students in 269 senior high school and university classes in six countries, and cross-validated with 1,594 senior high school students in 92 classes in Australia. Each SLEI scale exhibited satisfactory internal consistency reliability, discriminant validity, and factorial validity, and differentiated between the perceptions of students in different classes. A variety of applications with the new instrument furnished evidence about its usefulness and revealed that science laboratory classes are dominated by closed-ended activities; mean scores obtained on the Class form were consistently somewhat more favorable than on the corresponding Personal form; females generally held more favorable perceptions than males, but these differences were somewhat larger for the Personal form than the Class form; associations existed between attitudinal outcomes and laboratory environment dimensions; and the Class and Personal forms of the SLEI each accounted for unique variance in student outcomes which was independent of that accounted for by the other form.

Battelle's Marine Research Laboratory, Sequim

DOE Office of Scientific and Technical Information (OSTI.GOV)

Becker, C.D.; Strand, J.A.

Scientists at Battelle's Marine Research Laboratory (MRL) in Sequim, Washington study the effect of human activities on marine ecosystems, with emphasis on near shore and estuarine environments. The laboratory provides research and development assistance to industry and government agencies engaged in management of marine technologies, operation of coastal power utilities, protection of the marine environment, and related areas. This paper outlines and discusses the functions of Battelle's MRL, it's history, it's unique features, it's areas of expertise, it's current programs, and it's cooperating agencies.

Roles of laboratories and laboratory systems in effective tuberculosis programmes.

PubMed

Ridderhof, John C; van Deun, Armand; Kam, Kai Man; Narayanan, P R; Aziz, Mohamed Abdul

2007-05-01

Laboratories and laboratory networks are a fundamental component of tuberculosis (TB) control, providing testing for diagnosis, surveillance and treatment monitoring at every level of the health-care system. New initiatives and resources to strengthen laboratory capacity and implement rapid and new diagnostic tests for TB will require recognition that laboratories are systems that require quality standards, appropriate human resources, and attention to safety in addition to supplies and equipment. To prepare the laboratory networks for new diagnostics and expanded capacity, we need to focus efforts on strengthening quality management systems (QMS) through additional resources for external quality assessment programmes for microscopy, culture, drug susceptibility testing (DST) and molecular diagnostics. QMS should also promote development of accreditation programmes to ensure adherence to standards to improve both the quality and credibility of the laboratory system within TB programmes. Corresponding attention must be given to addressing human resources at every level of the laboratory, with special consideration being given to new programmes for laboratory management and leadership skills. Strengthening laboratory networks will also involve setting up partnerships between TB programmes and those seeking to control other diseases in order to pool resources and to promote advocacy for quality standards, to develop strategies to integrate laboratories functions and to extend control programme activities to the private sector. Improving the laboratory system will assure that increased resources, in the form of supplies, equipment and facilities, will be invested in networks that are capable of providing effective testing to meet the goals of the Global Plan to Stop TB.

The effects of monitoring environment on problem-solving performance.

PubMed

Laird, Brian K; Bailey, Charles D; Hester, Kim

2018-01-01

While effective and efficient solving of everyday problems is important in business domains, little is known about the effects of workplace monitoring on problem-solving performance. In a laboratory experiment, we explored the monitoring environment's effects on an individual's propensity to (1) establish pattern solutions to problems, (2) recognize when pattern solutions are no longer efficient, and (3) solve complex problems. Under three work monitoring regimes-no monitoring, human monitoring, and electronic monitoring-114 participants solved puzzles for monetary rewards. Based on research related to worker autonomy and theory of social facilitation, we hypothesized that monitored (versus non-monitored) participants would (1) have more difficulty finding a pattern solution, (2) more often fail to recognize when the pattern solution is no longer efficient, and (3) solve fewer complex problems. Our results support the first two hypotheses, but in complex problem solving, an interaction was found between self-assessed ability and the monitoring environment.

MDMA effects consistent across laboratories

PubMed Central

Kirkpatrick, Matthew G.; Baggott, Matthew J.; Mendelson, John E.; Galloway, Gantt P.; Liechti, Matthias E.; Hysek, Cédric M.; de Wit, Harriet

2014-01-01

Rationale Several laboratories have conducted placebo-controlled drug challenge studies with MDMA, providing a unique source of data to examine the reliability of the acute effects of the drug across subject samples and settings. We examined the subjective and physiological responses to the drug across three different laboratories, and investigated the influence of prior MDMA use. Methods Overall, 220 healthy volunteers with varying levels of previous MDMA experience participated in laboratory-based studies in which they received placebo or oral MDMA (1.5 mg/kg or 125 mg fixed dose) under double blind conditions. Cardiovascular and subjective effects were assessed before and repeatedly after drug administration. The studies were conducted independently by investigators in Basel, San Francisco and Chicago. Results Despite methodological differences between the studies and differences in the subjects' drug use histories, MDMA produced very similar cardiovascular and subjective effects across the sites. The participants' prior use of MDMA was inversely related to feeling `Any Drug Effect' only at sites testing more experienced users. Conclusions These data indicate that the pharmacological effects of MDMA are robust and highly reproducible across settings. There was also modest evidence for tolerance to the effects of MDMA in regular users. PMID:24633447

Spacecraft VHF Radio Propagation Analysis in Ocean Environments Including Atmospheric Effects

NASA Technical Reports Server (NTRS)

Hwu, Shian; Moreno, Gerardo; Desilva, Kanishka; Jih, CIndy

2010-01-01

The Communication Systems Simulation Laboratory (CSSL) at the National Aeronautics and Space Administration (NASA)/Johnson Space Center (JSC) is tasked to perform spacecraft and ground network communication system simulations. The CSSL has developed simulation tools that model spacecraft communication systems and the space/ground environment in which they operate. This paper is to analyze a spacecraft's very high frequency (VHF) radio signal propagation and the impact to performance when landing in an ocean. Very little research work has been done for VHF radio systems in a maritime environment. Rigorous Radio Frequency (RF) modeling/simulation techniques were employed for various environmental effects. The simulation results illustrate the significance of the environmental effects on the VHF radio system performance.

Roles of laboratories and laboratory systems in effective tuberculosis programmes

PubMed Central

van Deun, Armand; Kam, Kai Man; Narayanan, PR; Aziz, Mohamed Abdul

2007-01-01

Abstract Laboratories and laboratory networks are a fundamental component of tuberculosis (TB) control, providing testing for diagnosis, surveillance and treatment monitoring at every level of the health-care system. New initiatives and resources to strengthen laboratory capacity and implement rapid and new diagnostic tests for TB will require recognition that laboratories are systems that require quality standards, appropriate human resources, and attention to safety in addition to supplies and equipment. To prepare the laboratory networks for new diagnostics and expanded capacity, we need to focus efforts on strengthening quality management systems (QMS) through additional resources for external quality assessment programmes for microscopy, culture, drug susceptibility testing (DST) and molecular diagnostics. QMS should also promote development of accreditation programmes to ensure adherence to standards to improve both the quality and credibility of the laboratory system within TB programmes. Corresponding attention must be given to addressing human resources at every level of the laboratory, with special consideration being given to new programmes for laboratory management and leadership skills. Strengthening laboratory networks will also involve setting up partnerships between TB programmes and those seeking to control other diseases in order to pool resources and to promote advocacy for quality standards, to develop strategies to integrate laboratories’ functions and to extend control programme activities to the private sector. Improving the laboratory system will assure that increased resources, in the form of supplies, equipment and facilities, will be invested in networks that are capable of providing effective testing to meet the goals of the Global Plan to Stop TB. PMID:17639219

Hearing in Laboratory Animals: Strain Differences and Nonauditory Effects of Noise

PubMed Central

Parrish, Jennifer L.; Hughes, Larry F.; Toth, Linda A.; Caspary, Donald M.

2013-01-01

Hearing in laboratory animals is a topic that traditionally has been the domain of the auditory researcher. However, hearing loss and exposure to various environmental sounds can lead to changes in multiple organ systems, making what laboratory animals hear of consequence for researchers beyond those solely interested in hearing. For example, several inbred mouse strains commonly used in biomedical research (e.g., C57BL/6, DBA/2, and BALB/c) experience a genetically determined, progressive hearing loss that can lead to secondary changes in systems ranging from brain neurochemistry to social behavior. Both researchers and laboratory animal facility personnel should be aware of both strain and species differences in hearing in order to minimize potentially confounding variables in their research and to aid in the interpretation of data. Independent of genetic differences, acoustic noise levels in laboratory animal facilities can have considerable effects on the inhabitants. A large body of literature describes the nonauditory impact of noise on the biology and behavior of various strains and species of laboratory animals. The broad systemic effects of noise exposure include changes in endocrine and cardiovascular function, sleep–wake cycle disturbances, seizure susceptibility, and an array of behavioral changes. These changes are determined partly by species and strain; partly by noise intensity level, duration, predictability, and other characteristics of the sound; and partly by animal history and exposure context. This article reviews some of the basic strain and species differences in hearing and outlines how the acoustic environment affects different mammals. PMID:15766204

Computer and laboratory simulation of interactions between spacecraft surfaces and charged-particle environments

NASA Technical Reports Server (NTRS)

Stevens, N. J.

1979-01-01

Cases where the charged-particle environment acts on the spacecraft (e.g., spacecraft charging phenomena) and cases where a system on the spacecraft causes the interaction (e.g., high voltage space power systems) are considered. Both categories were studied in ground simulation facilities to understand the processes involved and to measure the pertinent parameters. Computer simulations are based on the NASA Charging Analyzer Program (NASCAP) code. Analytical models are developed in this code and verified against the experimental data. Extrapolation from the small test samples to space conditions are made with this code. Typical results from laboratory and computer simulations are presented for both types of interactions. Extrapolations from these simulations to performance in space environments are discussed.

Potential effect of fiddler crabs on organic matter distribution: A combined laboratory and field experimental approach

NASA Astrophysics Data System (ADS)

Natálio, Luís F.; Pardo, Juan C. F.; Machado, Glauco B. O.; Fortuna, Monique D.; Gallo, Deborah G.; Costa, Tânia M.

2017-01-01

Bioturbators play a key role in estuarine environments by modifying the availability of soil elements, which in turn may affect other organisms. Despite the importance of bioturbators, few studies have combined both field and laboratory experiments to explore the effects of bioturbators on estuarine soils. Herein, we assessed the bioturbation potential of fiddler crabs Leptuca leptodactyla and Leptuca uruguayensis in laboratory and field experiments, respectively. We evaluated whether the presence of fiddler crabs resulted in vertical transport of sediment, thereby altering organic matter (OM) distribution. Under laboratory conditions, the burrowing activity by L. leptodactyla increased the OM content in sediment surface. In the long-term field experiment with areas of inclusion and exclusion of L. uruguayensis, we did not observe influence of this fiddler crab in the vertical distribution of OM. Based on our results, we suggest that small fiddler crabs, such as the species used in these experiments, are potentially capable of alter their environment by transporting sediment and OM but such effects may be masked by environmental drivers and spatial heterogeneity under natural conditions. This phenomenon may be related to the small size of these species, which affects how much sediment is transported, along with the way OM interacts with biogeochemical and physical processes. Therefore, the net effect of these burrowing organisms is likely to be the result of a complex interaction with other environmental factors. In this sense, we highlight the importance of performing simultaneous field and laboratory experiments in order to better understanding the role of burrowing animals as bioturbators.

Report: EPA’s Radiation and Indoor Environments National Laboratory Should Improve Its Computer Room Security Controls

EPA Pesticide Factsheets

Report #12-P-0847, September 21, 2012.Our review of the security posture and in-place environmental controls of EPA’s Radiation and Indoor Environments National Laboratory computer room disclosed an array of security and environmental control deficiencies.

Nursing students' perceptions of factors influencing their learning environment in a clinical skills laboratory: A qualitative study.

PubMed

Haraldseid, Cecilie; Friberg, Febe; Aase, Karina

2015-09-01

The mastery of clinical skills learning is required to become a trained nurse. Due to limited opportunities for clinical skills training in clinical practice, undergraduate training at clinical skills laboratories (CSLs) is an essential part of nursing education. In a sociocultural learning perspective learning is situated in an environment. Growing student cohorts, rapid introduction of technology-based teaching methods and a shift from a teaching- to a learning-centered education all influence the environment of the students. These changes also affect CSLs and therefore compel nursing faculties to adapt to the changing learning environment. This study aimed to explore students' perceptions of their learning environment in a clinical skills laboratory, and to increase the knowledge base for improving CSL learning conditions identifying the most important environmental factors according to the students. An exploratory qualitative methodology was used. Nineteen second-year students enrolled in an undergraduate nursing program in Norway participated in the study. They took the same clinical skills course. Eight were part-time students (group A) and 11 were full-time students (group B). Focus group interviews and content analysis were conducted to capture the students' perception of the CSL learning environment. The study documents students' experience of the physical (facilities, material equipment, learning tools, standard procedures), psychosocial (expectations, feedback, relations) and organizational (faculty resources, course structure) factors that affect the CSL learning environment. Creating an authentic environment, facilitating motivation, and providing resources for multiple methods and repetitions within clinical skills training are all important for improving CSL learning environments from the student perspective. Copyright © 2015 Elsevier Ltd. All rights reserved.

The Effectiveness of Computer Supported versus Real Laboratory Inquiry Learning Environments on the Understanding of Direct Current Electricity among Pre-Service Elementary School Teachers

ERIC Educational Resources Information Center

Baser, Mustafa; Durmus, Soner

2010-01-01

The purpose of this study was to compare the changes in conceptual understanding of Direct Current Electricity (DCE) in virtual (VLE) and real laboratory environment (RLE) among pre-service elementary school teachers. A pre- and post-test experimental design was used with two different groups. One of the groups was randomly assigned to VLE (n =…

Safety | Argonne National Laboratory

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laboratory's ongoing effort to provide a safe and productive environment for employees, users, other site Skip to main content Argonne National Laboratory Toggle Navigation Toggle Search Energy Environment Careers Education Community Diversity Directory Energy Environment National Security User Facilities

ROBOTICS IN HAZARDOUS ENVIRONMENTS - REAL DEPLOYMENTS BY THE SAVANNAH RIVER NATIONAL LABORATORY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kriikku, E.; Tibrea, S.; Nance, T.

The Research & Development Engineering (R&DE) section in the Savannah River National Laboratory (SRNL) engineers, integrates, tests, and supports deployment of custom robotics, systems, and tools for use in radioactive, hazardous, or inaccessible environments. Mechanical and electrical engineers, computer control professionals, specialists, machinists, welders, electricians, and mechanics adapt and integrate commercially available technology with in-house designs, to meet the needs of Savannah River Site (SRS), Department of Energy (DOE), and other governmental agency customers. This paper discusses five R&DE robotic and remote system projects.

Rationale for cost-effective laboratory medicine.

PubMed Central

Robinson, A

1994-01-01

There is virtually universal consensus that the health care system in the United States is too expensive and that costs need to be limited. Similar to health care costs in general, clinical laboratory expenditures have increased rapidly as a result of increased utilization and inflationary trends within the national economy. Economic constraints require that a compromise be reached between individual welfare and limited societal resources. Public pressure and changing health care needs have precipitated both subtle and radical laboratory changes to more effectively use allocated resources. Responsibility for excessive laboratory use can be assigned primarily to the following four groups: practicing physicians, physicians in training, patients, and the clinical laboratory. The strategies to contain escalating health care costs have ranged from individualized physician education programs to government intervention. Laboratories have responded to the fiscal restraints imposed by prospective payment systems by attempting to reduce operational costs without adversely impacting quality. Although cost containment directed at misutilization and overutilization of existing services has conserved resources, to date, an effective cost control mechanism has yet to be identified and successfully implemented on a grand enough scale to significantly impact health care expenditures in the United States. PMID:8055467

Implementing Learning Assistants and Tutorials in the Laboratory Environment

NASA Astrophysics Data System (ADS)

Stewart, John; Henderson, Rachel; Miller, Paul

2016-03-01

This talk describes the results of a novel implementation of a Learning Assistant (LA) program where the LAs facilitated the presentation of the Tutorials in Introductory Physics as part of an otherwise traditional laboratory. LAs received both general training in the teaching of science and specific training in the presentation of the Tutorials. The LAs acted as the lead laboratory instructor for one hour each lab. The program required very little interaction from the lecturer. The program showed a substantial increase in learning gains on the Force and Motion Conceptual Inventory in the first semester course, but weaker improvement of learning gains on the Conceptual Survey of Electricity and Magnetism in the second semester course. Multiple linear regression showed that gender, student ability, and whether the student was on-sequence were significant regressors. The instructor was a substantial random effect (SD = 0 . 10), but the teaching assistant (SD = 0 . 00) and learning assistant (SD = 0 . 01) were much weaker random effects on the normalized gain. The instructor standing (tenure-track, teaching faculty, or adjunct) was a weakly significant regressor (p < 0 . 05).

Differences in the Gambling Behavior of Online and Non-Online Student Gamblers in a Controlled Laboratory Environment

PubMed Central

Montes, Kevin S.; Weatherly, Jeffrey N.

2016-01-01

Although research suggests that approximately 1 in 4 college students report having gambled online, few laboratory-based studies have been conducted enlisting online student gamblers. Moreover, it is unclear the extent to which differences in gambling behavior exist between online and non-online student gamblers. The current study examined if online gamblers would play more hands, commit more errors, and wager more credits than non-online student gamblers in a controlled, laboratory environment. Online (n = 19) and non-online (n = 26) student gamblers played video poker in three separate sessions and the number of hands played, errors committed, and credits wagered were recorded. Results showed that online student gamblers played more hands and committed more errors playing video poker than non-online student gamblers. The results from the current study extend previous research by suggesting that online gamblers engage in potentially more deleterious gambling behavior (e.g., playing more hands and committing more errors) than non-online gamblers. Additional research is needed to examine differences in the gambling behavior of online and non-online gamblers in a controlled, laboratory environment. PMID:27106027

Laboratory measures of methylphenidate effects in cocaine-dependent patients receiving treatment.

PubMed

Roache, J D; Grabowski, J; Schmitz, J M; Creson, D L; Rhoades, H M

2000-02-01

Two experiments examined the effects of methylphenidate in male and female patients enrolled in an outpatient treatment program for primary cocaine dependence. The first study was a component of a double-blind efficacy trial wherein 57 patients were first tested in a human laboratory for their initial responsiveness to medication. Patients were randomly assigned to receive either placebo or methylphenidate treatment and received their first dose in the human laboratory environment before continuing in outpatient treatment. Methylphenidate was given as a 20-mg sustained-release dose (twice daily) plus an additional 5-mg immediate-release dose combined with the morning dose. Methylphenidate increased heart rate and subjective ratings; however, the subjective effects were primarily of a "dysphoric" nature, and significant effects were limited to increases in anxiety, depression, and anger on the Profile of Mood States; shaky/jittery ratings on a visual analog scale; and dysphoria on the lysergic acid diethylamide (LSD) scale of the Addiction Research Center Inventory. Methylphenidate did not increase cocaine craving nor ratings suggesting abuse potential (i.e., Morphine-Benzedrine Group or drug-liking scores, etc.). None of the drug effects observed in the human laboratory was of clinical concern, and no subject was precluded from continuing in the outpatient study. After outpatient treatment completion, 12 patients were brought back into a second double-blind human laboratory study in which three doses (15, 30, and 60 mg) of immediate-release methylphenidate were administered in an ascending series preceded and followed by placebo. Methylphenidate produced dose-related increases in heart rate, subjective ratings of shaky/jittery, and LSD/dysphoria without significantly altering cocaine craving or stimulant euphoria ratings. These results suggest that stimulant substitution-type approaches to the treatment of cocaine dependence are not necessarily contraindicated

Engineering Laboratory Instruction in Virtual Environment--"eLIVE"

ERIC Educational Resources Information Center

Chaturvedi, Sushil; Prabhakaran, Ramamurthy; Yoon, Jaewan; Abdel-Salam, Tarek

2011-01-01

A novel application of web-based virtual laboratories to prepare students for physical experiments is explored in some detail. The pedagogy of supplementing physical laboratory with web-based virtual laboratories is implemented by developing a web-based tool, designated in this work as "eLIVE", an acronym for Engineering Laboratory…

Separating parental environment from seed size effects on next generation growth and development in Arabidopsis.

PubMed

Elwell, Angela L; Gronwall, David S; Miller, Nathan D; Spalding, Edgar P; Brooks, Tessa L Durham

2011-02-01

Plant growth and development is profoundly influenced by environmental conditions that laboratory experimentation typically attempts to control. However, growth conditions are not uniform between or even within laboratories and the extent to which these differences influence plant growth and development is unknown. Experiments with wild-type Arabidopsis thaliana were designed to quantify the influences of parental environment and seed size on growth and development in the next generation. A single lot of seed was planted in six environmental chambers and grown to maturity. The seed produced was mechanically sieved into small and large size classes then grown in a common environment and subjected to a set of assays spanning the life cycle. Analysis of variance demonstrated that seed size effects were particularly significant early in development, affecting primary root growth and gravitropism, but also flowering time. Parental environment affected progeny germination time, flowering and weight of seed the progeny produced. In some cases, the parental environment affected the magnitude of (interacted with) the observed seed size effects. These data indicate that life history circumstances of the parental generation can affect growth and development throughout the life cycle of the next generation to an extent that should be considered when performing genetic studies. © 2010 Blackwell Publishing Ltd.

Application of Emulsified Zero-Valent Iron to Marine Environments

NASA Technical Reports Server (NTRS)

Quinn, Jacqueline W.; Brooks, Kathleen B.; Geiger, Cherie L.; Clausen, Christian A.; Milum, Kristen M.

2006-01-01

Contamination of marine waters and sediments with heavy metals and dense non-aqueous phase liquids (DNAPLs) including chlorinated solvents, pesticides and PCBs pose ecological and human health risks through the potential of the contaminant to bioaccumulate in fish, shellfish and avian populations. The contaminants enter marine environments through improper disposal techniques and storm water runoff. Current remediation technologies for application to marine environments include costly dredging and off-site treatment of the contaminated media. Emulsified zero-valent iron (EZVI) has been proven to effectively degrade dissolved-phase and DNAPL-phase contaminants in freshwater environments on both the laboratory and field-scale level. Emulsified Zero-Valent Metal (EZVM) using metals such as iron and/or magnesium have been shown in the laboratory and on the bench scale to be effective at removing metals contamination in freshwater environments. The application to marine environments, however, is only just being explored. This paper discusses. the potential use of EZVI or EZVM in brackish and saltwater environments, with supporting laboratory data detailing its effectiveness on trichloroethylene, lead, copper, nickel and cadmium.

Development of a Tool to Recreate the Mars Science Laboratory Aerothermal Environment

NASA Technical Reports Server (NTRS)

Beerman, A. F.; Lewis, M. J.; Santos, J. A.; White, T. R.

2010-01-01

The Mars Science Laboratory will enter the Martian atmosphere in 2012 with multiple char depth sensors and in-depth thermocouples in its heatshield. The aerothermal environment experienced by MSL may be computationally recreated using the data from the sensors and a material response program, such as the Fully Implicit Ablation and Thermal (FIAT) response program, through the matching of the char depth and thermocouple predictions of the material response program to the sensor data. A tool, CHanging Inputs from the Environment of FIAT (CHIEF), was developed to iteratively change different environmental conditions such that FIAT predictions match within certain criteria applied to an external data set. The computational environment is changed by iterating on the enthalpy, pressure, or heat transfer coefficient at certain times in the trajectory. CHIEF was initially compared against arc-jet test data from the development of the MSL heatshield and then against simulated sensor data derived from design trajectories for MSL. CHIEF was able to match char depth and in-depth thermocouple temperatures within the bounds placed upon it for these cases. Further refinement of CHIEF to compare multiple time points and assign convergence criteria may improve accuracy.

Numerical modeling of zero-offset laboratory data in a strong topographic environment: results for a spectral-element method and a discretized Kirchhoff integral method

NASA Astrophysics Data System (ADS)

Favretto-Cristini, Nathalie; Tantsereva, Anastasiya; Cristini, Paul; Ursin, Bjørn; Komatitsch, Dimitri; Aizenberg, Arkady M.

2014-08-01

Accurate simulation of seismic wave propagation in complex geological structures is of particular interest nowadays. However conventional methods may fail to simulate realistic wavefields in environments with great and rapid structural changes, due for instance to the presence of shadow zones, diffractions and/or edge effects. Different methods, developed to improve seismic modeling, are typically tested on synthetic configurations against analytical solutions for simple canonical problems or reference methods, or via direct comparison with real data acquired in situ. Such approaches have limitations, especially if the propagation occurs in a complex environment with strong-contrast reflectors and surface irregularities, as it can be difficult to determine the method which gives the best approximation of the "real" solution, or to interpret the results obtained without an a priori knowledge of the geologic environment. An alternative approach for seismics consists in comparing the synthetic data with high-quality data collected in laboratory experiments under controlled conditions for a known configuration. In contrast with numerical experiments, laboratory data possess many of the characteristics of field data, as real waves propagate through models with no numerical approximations. We thus present a comparison of laboratory-scaled measurements of 3D zero-offset wave reflection of broadband pulses from a strong topographic environment immersed in a water tank with numerical data simulated by means of a spectral-element method and a discretized Kirchhoff integral method. The results indicate a good quantitative fit in terms of time arrivals and acceptable fit in amplitudes for all datasets.

Intelligent Performance Assessment of Students' Laboratory Work in a Virtual Electronic Laboratory Environment

ERIC Educational Resources Information Center

Achumba, I. E.; Azzi, D.; Dunn, V. L.; Chukwudebe, G. A.

2013-01-01

Laboratory work is critical in undergraduate engineering courses. It is used to integrate theory and practice. This demands that laboratory activities are synchronized with lectures to maximize their derivable learning outcomes, which are measurable through assessment. The typical high costs of the traditional engineering laboratory, which often…

Differences in the Gambling Behavior of Online and Non-online Student Gamblers in a Controlled Laboratory Environment.

PubMed

Montes, Kevin S; Weatherly, Jeffrey N

2017-03-01

Although research suggests that approximately 1 in 4 college students report having gambled online, few laboratory-based studies have been conducted enlisting online student gamblers. Moreover, it is unclear the extent to which differences in gambling behavior exist between online and non-online student gamblers. The current study examined if online gamblers would play more hands, commit more errors, and wager more credits than non-online student gamblers in a controlled, laboratory environment. Online (n = 19) and non-online (n = 26) student gamblers played video poker in three separate sessions and the number of hands played, errors committed, and credits wagered were recorded. Results showed that online student gamblers played more hands and committed more errors playing video poker than non-online student gamblers. The results from the current study extend previous research by suggesting that online gamblers engage in potentially more deleterious gambling behavior (e.g., playing more hands and committing more errors) than non-online gamblers. Additional research is needed to examine differences in the gambling behavior of online and non-online gamblers in a controlled, laboratory environment.

The Effects of Laboratory-Based and Field-Based Practicum Experience on Pre-Service Teachers' Self-Efficacy

ERIC Educational Resources Information Center

Gurvitch, Rachel; Metzler, Michael W.

2009-01-01

A well defined line of research has been conducted on the role of self-efficacy (Bandura, A. (1977). Self-efficacy: toward a unifying theory of behavioral change. "Psychological Review", 84, 191-215.) in teaching and learning environments. The purpose of this study was to examine the effect of Laboratory-Based (LB) and Field-Based (FB)…

Utica Shale Energy and Environment Laboratory Final Scientific/Technical Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cole, David Robert; Allen, Gerald Robert

The Ohio State University (OSU) was awarded a contract on October 1, 2014, from the Department of Energy National Energy Technology Laboratory (DOE-NETL) to develop the Utica Shale Energy and Environment Laboratory (USEEL) in the Utica-Point Pleasant shale play of the Appalachian Basin. It was designed to be an environmental and technology development lab that would enable the academic, industry, government, and non-governmental organization (NGO) research communities to better understand unconventional oil and gas (UOG) engineering practices and technology to increase production and safety, and decrease environmental effects. Political and economic consequences necessitated changes in project site location and design,more » from the Ohio State Eastern Agricultural Research Station (EARS) and the Muskingum Watershed Conservancy District (MWCD) in east-central Ohio to a site located at an Energy Corporation of America (ECA) Marcellus drill pad in Greene County, Pennsylvania. Although the overall project progressed little beyond planning and administration before termination on September 18, 2017, significant research and MS or PhD investigations were completed or continue today. An experimental study design for site specific and regional baseline assessments was developed utilizing ecoregions, United States Geological Survey (USGS) Hydraulic Unit Code watersheds, and GIS technology and databases. This can be utilized to build a defensible and scalable management and research framework for UOG investigations that can be extrapolated for predictive and comparative analyses. The most commonly mentioned perceived risks of shale energy development identified in a socioeconomic analysis included impacts to the environment and water resources, traffic and road deterioration, and crime. Economic benefits, such as the windfall wealth to residents, job opportunities, and the demand for hotels and restaurants emerged, as the main positive impact to the community. Preliminary

Student Perceptions of the Cell Biology Laboratory Learning Environment in Four Undergraduate Science Courses in Spain

ERIC Educational Resources Information Center

De Juan, Joaquin; Pérez-Cañaveras, Rosa M.; Segovia, Yolanda; Girela, Jose Luis; Martínez-Ruiz, Noemi; Romero-Rameta, Alejandro; Gómez-Torres, Maria José; Vizcaya-Moreno, M. Flores

2016-01-01

Cell biology is an academic discipline that organises and coordinates the learning of the structure, function and molecular composition of cells in some undergraduate biomedical programs. Besides course content and teaching methodologies, the laboratory environment is considered a key element in the teaching of and learning of cell biology. The…

Environment | Argonne National Laboratory

Science.gov Websites

Chemical Risk Management Environment True energy security depends on understanding the impact that energy whether scientists can unlock nature's design secrets The University of Chicago Weatherman Skilling draws Design Works ALIArgonne Leadership Institute CEESCenter for Electrochemical Energy Science CTRCenter for

Laboratory Studies on the Formation of Carbon-Bearing Molecules in Extraterrestrial Environments: From the Gas Phase to the Solid State

NASA Technical Reports Server (NTRS)

Jamieson, C. S.; Guo, Y.; Gu, X.; Zhang, F.; Bennett, C. J.; Kaiser, R. I.

2006-01-01

A detailed knowledge of the formation of carbon-bearing molecules in interstellar ices and in the gas phase of the interstellar medium is of paramount interest to understand the astrochemical evolution of extraterrestrial environments (1). This research also holds strong implications to comprehend the chemical processing of Solar System environments such as icy planets and their moons together with the atmospheres of planets and their satellites (2). Since the present composition of each interstellar and Solar System environment reflects the matter from which it was formed and the processes which have changed the chemical nature since the origin (solar wind, planetary magnetospheres, cosmic ray exposure, photolysis, chemical reactions), a detailed investigation of the physicochemical mechanisms altering the pristine environment is of paramount importance to grasp the contemporary composition. Once these underlying processes have been unraveled, we can identify those molecules, which belonged to the nascent setting, distinguish molecular species synthesized in a later stage, and predict the imminent chemical evolution of, for instance, molecular clouds. Laboratory experiments under controlled physicochemical conditions (temperature, pressure, chemical composition, high energy components) present ideal tools for simulating the chemical evolution of interstellar and Solar System environments. Here, laboratory experiments can predict where and how (reaction mechanisms; chemicals necessary) in extraterrestrial environments and in the interstellar medium complex, carbon bearing molecules can be formed on interstellar grains and in the gas phase. This paper overviews the experimental setups utilized in our laboratory to mimic the chemical processing of gas phase and solid state (ices) environments. These are a crossed molecular beams machine (3) and a surface scattering setup (4). We also present typical results of each setup (formation of amino acids, aldehydes, epoxides

The Y Chromosome Effect on Intermale Aggression in Mice Depends on the Maternal Environment

PubMed Central

Carlier, M.; Roubertoux, P. L.; Pastoret, C.

1991-01-01

Two parental strains of laboratory mice, NZB and CBA/H, were chosen for their differences in attack behavior. NZB have higher scores than CBA/H. An effect of the Y chromosome on attack behavior was determined for two maternal environments. Each male was tested once in a dyadic encounter with an A/J male as a standard opponent. The two reciprocal F(1)s and the four reciprocal backcrosses were used. In each group, the proportion of attacking males was used as the dependent variable. In the first experiment, the ovarian graft method was used to test for an effect of variation of the overall maternal environment: parental vs. F(1). The results demonstrated an interaction between the Y chromosome and the maternal environment. By use of the adoption method, it was shown in the second experiment that this maternal effect was probably postnatal (and not prenatal). PMID:1936960

Wiki Laboratory Notebooks: Supporting Student Learning in Collaborative Inquiry-Based Laboratory Experiments

NASA Astrophysics Data System (ADS)

Lawrie, Gwendolyn Angela; Grøndahl, Lisbeth; Boman, Simon; Andrews, Trish

2016-06-01

Recent examples of high-impact teaching practices in the undergraduate chemistry laboratory that include course-based undergraduate research experiences and inquiry-based experiments require new approaches to assessing individual student learning outcomes. Instructors require tools and strategies that can provide them with insight into individual student contributions to collaborative group/teamwork throughout the processes of experimental design, data analysis, display and communication of their outcomes in relation to their research question(s). Traditional assessments in the form of laboratory notebooks or experimental reports provide limited insight into the processes of collaborative inquiry-based activities. A wiki environment offers a collaborative domain that can potentially support collaborative laboratory processes and scientific record keeping. In this study, the effectiveness of the wiki in supporting laboratory learning and assessment has been evaluated through analysis of the content and histories for three consenting, participating groups of students. The conversational framework has been applied to map the relationships between the instructor, tutor, students and laboratory activities. Analytics that have been applied to the wiki platform include: character counts, page views, edits, timelines and the extent and nature of the contribution by each student to the wiki. Student perceptions of both the role and the impact of the wiki on their experiences and processes have also been collected. Evidence has emerged from this study that the wiki environment has enhanced co-construction of understanding of both the experimental process and subsequent communication of outcomes and data. A number of features are identified to support success in the use of the wiki platform for laboratory notebooks.

Exotic quantum effects in the laboratory?

PubMed

Schützhold, Ralf

2008-08-28

This article provides a brief (non-exhaustive) review of some recent developments regarding the theoretical and possibly experimental study of 'exotic' quantum effects in the laboratory with special emphasis on cosmological particle creation, Hawking radiation and the Unruh effect.

Alcohol craving in adolescents: bridging the laboratory and natural environment.

PubMed

Ramirez, Jason; Miranda, Robert

2014-04-01

Initial lab studies suggest that adolescent drinkers crave alcohol when presented with alcohol cues. Whether this effect generalizes to the natural environment, however, remains unknown, and studies have not examined whether craving predicts drinking among youths. This study builds on existing research by pairing controlled lab-based cue reactivity assessments (CRAs) with data collected in the natural environment using ecological momentary assessment (EMA) methods. We examined whether alcohol cues evoke craving among adolescent drinkers in the lab and natural environment, and tested the clinical relevance of craving during adolescence by examining the prospective association between craving and alcohol use. Non-treatment-seeking adolescent drinkers (N = 42; ages 15 to 20 years) completed a lab-based CRA followed by a 1-week EMA monitoring period. During the EMA period, youth were prompted randomly throughout the day to record momentary data on craving and contextual factors (e.g., alcohol cues, peers present). Alcohol cues elicited craving in the lab, and this effect generalized to the natural environment, especially among adolescents with more alcohol problems. In addition, craving predicted subsequent drinking levels in the natural environment. This study demonstrates the utility of pairing lab paradigms with EMA methods to better characterize adolescents' reactivity to alcohol cues. Results implicate craving as a clinically meaningful motivator for drinking among adolescents and highlight a potentially important target of pharmacological or behavioral intervention.

40 CFR 160.49 - Laboratory operation areas.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Laboratory operation areas. 160.49 Section 160.49 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS GOOD LABORATORY PRACTICE STANDARDS Facilities § 160.49 Laboratory operation areas. Separate laboratory...

40 CFR 160.49 - Laboratory operation areas.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Laboratory operation areas. 160.49 Section 160.49 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS GOOD LABORATORY PRACTICE STANDARDS Facilities § 160.49 Laboratory operation areas. Separate laboratory...

Studying the Earth's Environment from Space: Computer Laboratory Exercised and Instructor Resources

NASA Technical Reports Server (NTRS)

Smith, Elizabeth A.; Alfultis, Michael

1998-01-01

Studying the Earth's Environment From Space is a two-year project to develop a suite of CD-ROMs containing Earth System Science curriculum modules for introductory undergraduate science classes. Lecture notes, slides, and computer laboratory exercises, including actual satellite data and software, are being developed in close collaboration with Carla Evans of NASA GSFC Earth Sciences Directorate Scientific and Educational Endeavors (SEE) project. Smith and Alfultis are responsible for the Oceanography and Sea Ice Processes Modules. The GSFC SEE project is responsible for Ozone and Land Vegetation Modules. This document constitutes a report on the first year of activities of Smith and Alfultis' project.

Looking after the Land: The Navajo Dryland Environments Laboratory Researches the Environmental Needs of the Navajo Nation.

ERIC Educational Resources Information Center

Semken, Steven C.

1992-01-01

Describes the formation and operations of the Navajo Dryland Environments Laboratory (NDEL). NDEL, established by the Waste-Management Education and Research Consortium of New Mexico on the campus of Navajo Community College, focuses on environmental geology, hydrology, and resource management of the Colorado Plateau drylands. (DMM)

Initiatives toward effective decision making and laboratory use.

PubMed

Benson, E S

1980-09-01

Escalating health care costs constitute a public issue of paramount importance today, Among the leading growth factors in this rise is the cost of hospital services, notably laboratory services. With respect to the clinical laboratory, rising costs appear to be almost entirely attributable to expanding utilization and introduction of new services. The clinical laboratory has gone through a technological revolution in two decades that has changed it from a largely manual to a highly automated system of great speed and capacity. This change had produced a change in the style of providing services, a change that includes the provision of quantities of unsolicited data. A parallel change in the style of use of the laboratory has taken place on the part of patient care physicians from a relatively sparing, problem oriented use pattern to a relatively lavish, data oriented one. These reciprocal changes have transformed medicine, in the United States, at least, into a relatively high laboratory use culture. Abandonment of the new technology and return to a simpler, more primitive laboratory world would be a drastic and most inappropriate response to the new situation. Furthermore, arbitrary measures such as rationing, quotas, and tariffs are, if enacted, almost certain to fail. The most effective long term strategies, though more demanding of time and effort, lie through modification of physician behavior through the pathways of education and research. Education and research initiatives now in progress can in time influence laboratory use patterns of physicians at all career levels, improving the logic of test use and providing more strategic, prudent, and cost effective overall laboratory utilization practices. These approaches will require much improved communication between laboratory and bedside and a new intense involvement of laboratory physicians and scientists in the tasks of helping to improve the use of laboratory tests and laboratory data.

The Effect of Guided-Inquiry Laboratory Experiments on Science Education Students' Chemistry Laboratory Attitudes, Anxiety and Achievement

ERIC Educational Resources Information Center

Ural, Evrim

2016-01-01

The study aims to search the effect of guided inquiry laboratory experiments on students' attitudes towards chemistry laboratory, chemistry laboratory anxiety and their academic achievement in the laboratory. The study has been carried out with 37 third-year, undergraduate science education students, as a part of their Science Education Laboratory…

Post-flight Analysis of Mars Science Laboratory Entry Aerothermal Environment and Thermal Protection System Response

NASA Technical Reports Server (NTRS)

White, Todd Richard; Mahazari, Milad; Bose, Deepak; Santos, Jose Antonio

2013-01-01

The Mars Science Laboratory successfully landed on the Martian surface on August 5th, 2012. The rover was protected from the extreme heating environments of atmospheric entry by an ablative heatshield. This Phenolic Impregnated Carbon Ablator heatshield was instrumented with a suite of embedded thermocouples, isotherm sensors, and pressure transducers. The sensors monitored the in-depth ablator response, as well as the surface pressure at discrete locations throughout the hypersonic deceleration. This paper presents a comparison of the flight data with post-entry estimates. An assessment of the aerothermal environments, as well as the in-depth response of the heatshield material is made, and conclusions regarding the overall performance of the ablator at the suite locations are presented.

A qualitative case study of instructional support for web-based simulated laboratory exercises in online college chemistry laboratory courses

NASA Astrophysics Data System (ADS)

Schulman, Kathleen M.

This study fills a gap in the research literature regarding the types of instructional support provided by instructors in online introductory chemistry laboratory courses that employ chemistry simulations as laboratory exercises. It also provides information regarding students' perceptions of the effectiveness of that instructional support. A multiple case study methodology was used to carry out the research. Two online introductory chemistry courses were studied at two community colleges. Data for this study was collected using phone interviews with faculty and student participants, surveys completed by students, and direct observation of the instructional designs of instructional support in the online Blackboard web sites and the chemistry simulations used by the participating institutions. The results indicated that the instructors provided multiple types of instructional support that correlated with forms of effective instructional support identified in the research literature, such as timely detailed feedback, detailed instructions for the laboratory experiments, and consistency in the instructional design of lecture and laboratory course materials, including the chemistry lab simulation environment. The students in one of these courses identified the following as the most effective types of instructional support provided: the instructor's feedback, opportunities to apply chemistry knowledge in the chemistry lab exercises, detailed procedures for the simulated laboratory exercises, the organization of the course Blackboard sites and the chemistry lab simulation web sites, and the textbook homework web sites. Students also identified components of instructional support they felt were missing. These included a desire for more interaction with the instructor, more support for the simulated laboratory exercises from the instructor and the developer of the chemistry simulations, and faster help with questions about the laboratory exercises or experimental

Germination of Ocotea pulchella (Nees) Mez (Lauraceae) seeds in laboratory and natural restinga environment conditions.

PubMed

Pires, L A; Cardoso, V J M; Joly, C A; Rodrigues, R R

2009-08-01

The germination response of Ocotea pulchella (Nees) Mez seeds to light, temperature, water level and pulp presence is introduced. The laboratory assays were carried out in germination chambers and thermal-gradient apparatus, whereas the field assays were performed in environments with distinct light, temperature and soil moisture conditions within a permanent parcel of Restinga forest of the Parque Estadual da Ilha do Cardoso, Cananéia, São Paulo. The seeds do not exhibit dormancy, they are non photoblastic, and a loss of viability in dry stored seeds can be related to a decrease in water content of the seed. The presence of the pulp and the flooded substratum influenced negatively the germination of O. pulchella seeds tested in the laboratory. Otherwise, light and temperature probably are not limiting factors of the germination of O. pulchella seeds in the natural environment of Restinga. The optimum temperature range for germination of Ocotea pulchella seeds was 20 to 32 degrees C, the minimum or base temperature estimated was 11 degrees C and the maximum ranged between 33 and 42 degrees C. The isotherms exhibited a sigmoidal pattern well described by the Weibull model in the sub-optimal temperature range. The germinability of O. pulchella seeds in the understorey, both in wet and dry soil, was higher than in gaps. Germination was not affected by fluctuations in soil moisture content in the understorey environment, whereas in gaps, germination was higher in wet soils. Thus, the germination of this species involves the interaction of two or more factors and it cannot be explained by a single factor.

Effect of Light Water Reactor Water Environments on the Fatigue Life of Reactor Materials

DOE PAGES

Chopra, O. K.; Stevens, G. L.; Tregoning, R.; ...

2017-10-06

The American Society of Mechanical Engineers (ASME) Boiler and Pressure Vessel Code (Code) provides rules for the design of Class 1 components of nuclear power plants. Figures I-9.1 through I-9.6 of Appendix I to Section III of the Code specify fatigue design curves for applicable structural materials. However, the Code design curves do not explicitly address the effects of light water reactor (LWR) water environments. Existing fatigue strain-vs.-life (ε-N) laboratory data illustrate potentially significant effects of LWR water environments on the fatigue resistance of pressure vessel and piping steels. Extensive studies have been conducted at Argonne National Laboratory and elsewheremore » since 1990 to investigate the effects of LWR environments on the fatigue life of piping and pressure vessel steels. This article summarizes the results of these studies. Existing fatigue ε-N data were evaluated to identify the various material, environmental, and loading conditions that influence fatigue crack initiation; a methodology for estimating fatigue lives as a function of these parameters was developed. The effects were incorporated into the ASME Code Section III fatigue evaluations in terms of an environmental correction factor, F en, which is defined as the ratio of fatigue life in air at room temperature to the fatigue life in the LWR water environment at reactor operating temperatures. Available fatigue data were used to develop fatigue design curves for carbon and low-alloy steels, austenitic stainless steels, and nickel-chromium-iron (NiCr-Fe) alloys and their weld metals in air at room temperature. A review of the Code Section III fatigue adjustment factors of 2 on strain and 20 on life is also presented and the possible conservatism inherent in the choice of these adjustment factors is evaluated. A brief description of potential effects of neutron irradiation on fatigue crack initiation for these structural materials is also presented.« less

Effect of Light Water Reactor Water Environments on the Fatigue Life of Reactor Materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chopra, O. K.; Stevens, G. L.; Tregoning, R.

The American Society of Mechanical Engineers (ASME) Boiler and Pressure Vessel Code (Code) provides rules for the design of Class 1 components of nuclear power plants. Figures I-9.1 through I-9.6 of Appendix I to Section III of the Code specify fatigue design curves for applicable structural materials. However, the Code design curves do not explicitly address the effects of light water reactor (LWR) water environments. Existing fatigue strain-vs.-life (ε-N) laboratory data illustrate potentially significant effects of LWR water environments on the fatigue resistance of pressure vessel and piping steels. Extensive studies have been conducted at Argonne National Laboratory and elsewheremore » since 1990 to investigate the effects of LWR environments on the fatigue life of piping and pressure vessel steels. This article summarizes the results of these studies. Existing fatigue ε-N data were evaluated to identify the various material, environmental, and loading conditions that influence fatigue crack initiation; a methodology for estimating fatigue lives as a function of these parameters was developed. The effects were incorporated into the ASME Code Section III fatigue evaluations in terms of an environmental correction factor, F en, which is defined as the ratio of fatigue life in air at room temperature to the fatigue life in the LWR water environment at reactor operating temperatures. Available fatigue data were used to develop fatigue design curves for carbon and low-alloy steels, austenitic stainless steels, and nickel-chromium-iron (NiCr-Fe) alloys and their weld metals in air at room temperature. A review of the Code Section III fatigue adjustment factors of 2 on strain and 20 on life is also presented and the possible conservatism inherent in the choice of these adjustment factors is evaluated. A brief description of potential effects of neutron irradiation on fatigue crack initiation for these structural materials is also presented.« less

Laboratory safety handbook

USGS Publications Warehouse

Skinner, E.L.; Watterson, C.A.; Chemerys, J.C.

1983-01-01

Safety, defined as 'freedom from danger, risk, or injury,' is difficult to achieve in a laboratory environment. Inherent dangers, associated with water analysis and research laboratories where hazardous samples, materials, and equipment are used, must be minimized to protect workers, buildings, and equipment. Managers, supervisors, analysts, and laboratory support personnel each have specific responsibilities to reduce hazards by maintaining a safe work environment. General rules of conduct and safety practices that involve personal protection, laboratory practices, chemical handling, compressed gases handling, use of equipment, and overall security must be practiced by everyone at all levels. Routine and extensive inspections of all laboratories must be made regularly by qualified people. Personnel should be trained thoroughly and repetitively. Special hazards that may involve exposure to carcinogens, cryogenics, or radiation must be given special attention, and specific rules and operational procedures must be established to deal with them. Safety data, reference materials, and texts must be kept available if prudent safety is to be practiced and accidents prevented or minimized.

40 CFR 792.49 - Laboratory operation areas.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 31 2010-07-01 2010-07-01 true Laboratory operation areas. 792.49 Section 792.49 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT (CONTINUED) GOOD LABORATORY PRACTICE STANDARDS Facilities § 792.49 Laboratory operation areas...

Effects of commercial aircraft operating environment on composite materials

NASA Technical Reports Server (NTRS)

Chapman, A. J.; Hoffman, D. J.; Hodges, W. T.

1980-01-01

Long term effects of commercial aircraft operating environment on the properties and durability of composite materials are being systematically explored. Composite specimens configured for various mechanical property tests are exposed to environmental conditions on aircraft in scheduled airline service, on racks at major airports, and to controlled environmental conditions in the laboratory. Results of tests following these exposures will identify critical parameters affecting composite durability, and correlation of the data will aid in developing methods for predicting durability. Interim results of these studies show that mass change of composite specimens on commercial aircraft depends upon the regional climate and season, and that mass loss from composite surfaces due to ultraviolet radiation can be largely prevented by aircraft paint.

Eye protection in dental laboratories.

PubMed

Palenik, C J

1997-09-01

Many dental laboratory procedures increase the chances of serious eye injury. This would include traumatic injuries due to projectiles or through exposure to harsh chemicals or heat and infections from contact with patient body fluids. To help assure a safer working environment, awareness of the need for eye protection must be established and maintained by all laboratory personnel. The purpose of this article are: 1) to list the applicable federal regulations concerning eye safety in dental laboratory workplaces; 2) to describe the various types of appropriate eyewear; and 3) to identify which protective devices best prevent exposure to specific types of hazards. The goal of this article is to help dental laboratories with their employee safety programs, especially concerning the selection of protective eyewear. Such programs must include engineering controls and work practice controls plus appropriate personal protective equipment. Laboratories today must comply with safety mandates in the most effective and efficient manner.

Smart Electronic Laboratory Notebooks for the NIST Research Environment.

PubMed

Gates, Richard S; McLean, Mark J; Osborn, William A

2015-01-01

Laboratory notebooks have been a staple of scientific research for centuries for organizing and documenting ideas and experiments. Modern laboratories are increasingly reliant on electronic data collection and analysis, so it seems inevitable that the digital revolution should come to the ordinary laboratory notebook. The most important aspect of this transition is to make the shift as comfortable and intuitive as possible, so that the creative process that is the hallmark of scientific investigation and engineering achievement is maintained, and ideally enhanced. The smart electronic laboratory notebooks described in this paper represent a paradigm shift from the old pen and paper style notebooks and provide a host of powerful operational and documentation capabilities in an intuitive format that is available anywhere at any time.

Smart Electronic Laboratory Notebooks for the NIST Research Environment

PubMed Central

Gates, Richard S.; McLean, Mark J.; Osborn, William A.

2015-01-01

Laboratory notebooks have been a staple of scientific research for centuries for organizing and documenting ideas and experiments. Modern laboratories are increasingly reliant on electronic data collection and analysis, so it seems inevitable that the digital revolution should come to the ordinary laboratory notebook. The most important aspect of this transition is to make the shift as comfortable and intuitive as possible, so that the creative process that is the hallmark of scientific investigation and engineering achievement is maintained, and ideally enhanced. The smart electronic laboratory notebooks described in this paper represent a paradigm shift from the old pen and paper style notebooks and provide a host of powerful operational and documentation capabilities in an intuitive format that is available anywhere at any time. PMID:26958447

A Laboratory Exercise to Assess Transpiration.

ERIC Educational Resources Information Center

Schrock, Gould F.

1982-01-01

Procedures are outlined for a laboratory exercise in which students use a gravimetric method to determine the rate of transpiration in sunflower seedlings. Discusses the data in terms of the effectiveness of stomatal openings, mechanisms for water movement in plants, and the role of transpiration in the environment. (DC)

Nespoli installs ALTEA-SHIELD Hardware in the US Laboratory

NASA Image and Video Library

2011-04-23

ISS027-E-017245 (23 April 2011) --- European Space Agency astronaut Paolo Nespoli, Expedition 27 flight engineer, works with Anomalous Long Term Effects on Astronauts (ALTEA) Shield isotropic equipment in the Destiny laboratory of the International Space Station. ALTEA-Shield isotropic dosimetry uses existing ALTEA hardware to survey the radiation environment in the Destiny laboratory in 3D. It also measures the effectiveness and shielding properties of several materials with respect to the perception of anomalous light flashes.

Nespoli installs ALTEA-SHIELD Hardware in the US Laboratory

NASA Image and Video Library

2011-04-23

ISS027-E-017246 (23 April 2011) --- European Space Agency astronaut Paolo Nespoli, Expedition 27 flight engineer, works with Anomalous Long Term Effects on Astronauts (ALTEA) Shield isotropic equipment in the Destiny laboratory of the International Space Station. ALTEA-Shield isotropic dosimetry uses existing ALTEA hardware to survey the radiation environment in the Destiny laboratory in 3D. It also measures the effectiveness and shielding properties of several materials with respect to the perception of anomalous light flashes.

Nespoli photographs ALTEA-SHIELD Hardware in the US Laboratory

NASA Image and Video Library

2011-04-23

ISS027-E-017237 (23 April 2011) --- European Space Agency astronaut Paolo Nespoli, Expedition 27 flight engineer, works with Anomalous Long Term Effects on Astronauts (ALTEA) Shield isotropic equipment in the Destiny laboratory of the International Space Station. ALTEA-Shield isotropic dosimetry uses existing ALTEA hardware to survey the radiation environment in the Destiny laboratory in 3D. It also measures the effectiveness and shielding properties of several materials with respect to the perception of anomalous light flashes.

Nespoli installs ALTEA-SHIELD Hardware in the US Laboratory

NASA Image and Video Library

2011-04-23

ISS027-E-017249 (23 April 2011) --- European Space Agency astronaut Paolo Nespoli, Expedition 27 flight engineer, works with Anomalous Long Term Effects on Astronauts (ALTEA) Shield isotropic equipment in the Destiny laboratory of the International Space Station. ALTEA-Shield isotropic dosimetry uses existing ALTEA hardware to survey the radiation environment in the Destiny laboratory in 3D. It also measures the effectiveness and shielding properties of several materials with respect to the perception of anomalous light flashes.

Nespoli photographs ALTEA-SHIELD Hardware in the US Laboratory

NASA Image and Video Library

2011-04-23

ISS027-E-017236 (23 April 2011) --- European Space Agency astronaut Paolo Nespoli, Expedition 27 flight engineer, works with Anomalous Long Term Effects on Astronauts (ALTEA) Shield isotropic equipment in the Destiny laboratory of the International Space Station. ALTEA-Shield isotropic dosimetry uses existing ALTEA hardware to survey the radiation environment in the Destiny laboratory in 3D. It also measures the effectiveness and shielding properties of several materials with respect to the perception of anomalous light flashes.

Cross-fostering: Elucidating the effects of gene×environment interactions on phenotypic development.

PubMed

McCarty, Richard

2017-02-01

Cross-fostering of litters from soon after birth until weaning is a valuable tool to study the ways in which gene×environment interactions program the development of neural, physiological and behavioral characteristics of mammalian species. In laboratory mice and rats, the primary focus of this review, cross-fostering of litters between mothers of different strains or treatment groups (intraspecific) or between mothers of different species (interspecific) has been conducted over the past 9 decades. Areas of particular interest have included maternal effects on emotionality, social preferences, responses to stressful stimulation, nutrition and growth, blood pressure regulation, and epigenetic effects on brain development and behavior. Results from these areas of research highlight the critical role of the postnatal maternal environment in programming the development of offspring phenotypic characteristics. In addition, experimental paradigms that have included cross-fostering have permitted investigators to tease apart prenatal versus postnatal effects of various treatments on offspring development and behavior. Copyright © 2016 Elsevier Ltd. All rights reserved.

THE EFFECT OF AMOUNT OF CRUDE OIL ON EXTENT OF ITS BIODEGRADATION IN OPEN WATER- AND SANDY BEACH- LABORATORY SIMULATIONS

EPA Science Inventory

Lepo, J.E., C. R. Cripe, J.L. Kavanaugh, S. Zhang and G.P. Norton. 2003. Effect of Amount of Crude Oil on Extent of Its Biodegradation in Open Water- and Sandy Beach-Laboratory Simulations. Environ. Technol. 24(10):1291-1302. (ERL,GB 1109).

We examined the biodegradation ...

An investigation into the effect of playback environment on perception of sonic booms when heard indoors

NASA Astrophysics Data System (ADS)

Carr, Daniel; Davies, Patricia

2015-10-01

Aircraft manufacturers are interested in designing and building a new generation of supersonic aircraft that produce shaped sonic booms of lower peak amplitude than booms created by current supersonic aircraft. To determine if the noise exposure from these "low"booms is more acceptable to communities, new laboratory testing to evaluate people's responses must occur. To guide supersonic aircraft design, objective measures that predict human response to modified sonic boom waveforms and other impulsive sounds are needed. The present research phase is focused on understanding people's reactions to booms when heard inside, and therefore includes consideration of the effects of house type and the indoor acoustic environment. A test was conducted in NASA Langley's Interior Effects Room (IER), with the collaboration of NASA Langley engineers. This test was focused on the effects of low-frequency content and of vibration, and subjects sat in a small living room environment. A second test was conducted in a sound booth at Purdue University, using similar sounds played back over earphones. The sounds in this test contained less very-low-frequency energy due to limitations in the playback, and the laboratory setting is a less natural environment. For the purpose of comparison, and to improve the robustness of the model, both sonic booms and other more familiar transient sounds were used in the tests. The design of the tests and the signals are briefly described, and the results of both tests will be presented.

Effects of diversity in olfactory environment on children's sense of smell.

PubMed

Martinec Nováková, Lenka; Fialová, Jitka; Havlíček, Jan

2018-02-13

Diversity in children's everyday olfactory environment may affect the development of their olfactory abilities and odor awareness. To test this, we collected data on olfactory abilities using the Sniffin' Sticks and odor awareness with Children's Olfactory Behaviors in Everyday Life Questionnaire in 153 preschool children and retested them one and a half year later. Parents completed an inventory on children's exposure to a variety of odors and on their own odor awareness using the Odor Awareness Scale. We controlled for the effects of age and verbal fluency on the children's performance. We found that the children's odor identification and discrimination scores differed as a function of parental odor awareness. Although these effects were rather small, they were commensurate in size with those of gender and age. To the best of our knowledge, this study is the first to present evidence that diversity in children's olfactory environment affects variation in their olfactory abilities and odor awareness. We suggest that future studies consider the long-term impact of perceptual learning out of the laboratory and its consequences for olfactory development.

Electronic laboratory notebooks progress and challenges in implementation.

PubMed

Machina, Hari K; Wild, David J

2013-08-01

Electronic laboratory notebooks (ELNs) are increasingly replacing paper notebooks in life science laboratories, including those in industry, academic settings, and hospitals. ELNs offer significant advantages over paper notebooks, but adopting them in a predominantly paper-based environment is usually disruptive. The benefits of ELN increase when they are integrated with other laboratory informatics tools such as laboratory information management systems, chromatography data systems, analytical instrumentation, and scientific data management systems, but there is no well-established path for effective integration of these tools. In this article, we review and evaluate some of the approaches that have been taken thus far and also some radical new methods of integration that are emerging.

The OSHA hazardous chemical occupational exposure standard for laboratories.

PubMed

Armbruster, D A

1991-01-01

OSHA's chemical occupational exposure standard for laboratories is an outgrowth of the previously issued Hazard Communication Standard. The standard relieves laboratories from complying with general industry standards but does require compliance with specific laboratory guidelines. The heart of the standard is the creation of a Chemical Hygiene Plan (CHP). The CHP addresses major issues such as safety equipment and procedures, work practices, training, the designation of a chemical hygiene officer, and the provision of medical consultation and examination for affected employees. This new standard, in full effect as of January 31, 1991, presents yet another regulatory challenge to laboratory managers but also ensures a safer environment for laboratory workers.

The laboratory domestication of Caenorhabditis elegans.

PubMed

Sterken, Mark G; Snoek, L Basten; Kammenga, Jan E; Andersen, Erik C

2015-05-01

Model organisms are of great importance to our understanding of basic biology and to making advances in biomedical research. However, the influence of laboratory cultivation on these organisms is underappreciated, and especially how that environment can affect research outcomes. Recent experiments led to insights into how the widely used laboratory reference strain of the nematode Caenorhabditis elegans compares with natural strains. Here we describe potential selective pressures that led to the fixation of laboratory-derived alleles for the genes npr-1, glb-5, and nath-10. These alleles influence a large number of traits, resulting in behaviors that affect experimental interpretations. Furthermore, strong phenotypic effects caused by these laboratory-derived alleles hinder the discovery of natural alleles. We highlight strategies to reduce the influence of laboratory-derived alleles and to harness the full power of C. elegans. Copyright © 2015 Elsevier Ltd. All rights reserved.

OSHA Laboratory Standard: Driving Force for Laboratory Safety!

ERIC Educational Resources Information Center

Roy, Kenneth R.

2000-01-01

Discusses the Occupational Safety and Health Administration's (OSHA's) Laboratory Safety Standards as the major driving force in establishing and maintaining a safe working environment for teachers and students. (Author)

Meta-analysis of the effectiveness of computer-based laboratory versus traditional hands-on laboratory in college and pre-college science instructions

NASA Astrophysics Data System (ADS)

Onuoha, Cajetan O.

The purpose of this research study was to determine the overall effectiveness of computer-based laboratory compared with the traditional hands-on laboratory for improving students' science academic achievement and attitudes towards science subjects at the college and pre-college levels of education in the United States. Meta-analysis was used to synthesis the findings from 38 primary research studies conducted and/or reported in the United States between 1996 and 2006 that compared the effectiveness of computer-based laboratory with the traditional hands-on laboratory on measures related to science academic achievements and attitudes towards science subjects. The 38 primary research studies, with total subjects of 3,824 generated a total of 67 weighted individual effect sizes that were used in this meta-analysis. The study found that computer-based laboratory had small positive effect sizes over the traditional hands-on laboratory (ES = +0.26) on measures related to students' science academic achievements and attitudes towards science subjects (ES = +0.22). It was also found that computer-based laboratory produced more significant effects on physical science subjects compared to biological sciences (ES = +0.34, +0.17).

Nursing students' experiences of and satisfaction with the clinical learning environment: the role of educational models in the simulation laboratory and in clinical practice.

PubMed

Cremonini, Valeria; Ferri, Paola; Artioli, Giovanna; Sarli, Leopoldo; Piccioni, Enrico; Rubbi, Ivan

2015-01-01

Student satisfaction is an important element of the effectiveness of clinical placement, but there is little consensus in the literature as to the preferred model of clinical experience for undergraduate nursing students. The aim of this study was assess, for each academic year, students' perception of the roles of nurse teachers (NT) and clinical nurse supervisors (CNS) who perform tutoring in both apprenticeship and laboratories and to identify and evaluate students' satisfaction with the environment of clinical learning. This analytic cross-sectional study was conducted in a sample of 173 nursing students in the Northern Italy. The research instrument used is the Clinical learning environment, supervision and nurse teacher (CLES+T) evaluation scale. Data were statistically analysed. 94% of our sample answered questionnaires. Students expressed a higher level of satisfaction with their training experiences. The highest mean value was in the sub-dimension "Pedagogical atmosphere on the ward". Third year students expressed higher satisfaction levels in their relationship with the CNS and lower satisfaction levels in their relationship with the NT. This result may be due to the educational model that is adopted in the course, in which the simulation laboratory didactic activities of the third year are conducted by CNS, who also supervises experiences of clinical learning in the clinical practice. The main finding in this study was that the students' satisfaction with the supervisory relationship and the role of NT depend on how supervision in the clinical practice and in the simulation laboratory is organized.

The laboratory workforce shortage: a managerial perspective.

PubMed

Cortelyou-Ward, Kendall; Ramirez, Bernardo; Rotarius, Timothy

2011-01-01

Most clinical laboratories in the nation report severe difficulties in recruitment and retention of most types of personnel. Other important factors impacting this problem include work complexities, increased automation, and a graying workforce. As a further challenge, institutional needs for clinical laboratory personnel are expected to grow significantly in the next decade. This article examines the current situation of the clinical laboratory workforce. It analyzes the different types of personnel; the managerial, supervision, and line positions that are key for different types of laboratories; the job outlook and recent projections for different types of staff; and the current issues, trends, and challenges of the laboratory workforce. Laboratory managers need to take action with strategies suggested for overcoming these challenges. Most importantly, they need to become transformational leaders by developing effective staffing models, fostering healthy and productive work environments, and creating value with a strategic management culture and implementation of knowledge management.

The effect of stimulus intensity on response time and accuracy in dynamic, temporally constrained environments.

PubMed

Causer, J; McRobert, A P; Williams, A M

2013-10-01

The ability to make accurate judgments and execute effective skilled movements under severe temporal constraints are fundamental to elite performance in a number of domains including sport, military combat, law enforcement, and medicine. In two experiments, we examine the effect of stimulus strength on response time and accuracy in a temporally constrained, real-world, decision-making task. Specifically, we examine the effect of low stimulus intensity (black) and high stimulus intensity (sequin) uniform designs, worn by teammates, to determine the effect of stimulus strength on the ability of soccer players to make rapid and accurate responses. In both field- and laboratory-based scenarios, professional soccer players viewed developing patterns of play and were required to make a penetrative pass to an attacking player. Significant differences in response accuracy between uniform designs were reported in laboratory- and field-based experiments. Response accuracy was significantly higher in the sequin compared with the black uniform condition. Response times only differed between uniform designs in the laboratory-based experiment. These findings extend the literature into a real-world environment and have significant implications for the design of clothing wear in a number of domains. © 2012 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Nespoli works with ALTEA-SHIELD Hardware in the US Laboratory

NASA Image and Video Library

2011-04-23

ISS027-E-017243 (23 April 2011) --- European Space Agency astronaut Paolo Nespoli, Expedition 27 flight engineer, works with Anomalous Long Term Effects on Astronauts (ALTEA) Shield isotropic equipment in the Destiny laboratory of the International Space Station. ALTEA-Shield isotropic dosimetry uses existing ALTEA hardware to survey the radiation environment in the Destiny laboratory in 3D. It also measures the effectiveness and shielding properties of several materials with respect to the perception of anomalous light flashes.

Space Environment Effects on Materials : An Overview

NASA Technical Reports Server (NTRS)

Garrett, Henry B.

2006-01-01

A general overview on the space environment and its effects on materials is presented. The topics include: 1) Impact of Space Effects on Spacecraft Costs; 2) Space Environment Effects on Spacecraft by Source; 3) Primary Source of Space Effects: The Sun; 4) The Earth's Environment; 5) Trapped Radiation Belts; 6) Aurora Are Everywhere; 7) Spacecraft Interactions; 8) Atmospheric Effects; 9) Contaminant Effects on Materials; 10) Meteoroid/Debris Effects on Materials; 11) Spacecraft Surface Charging; 12) Surface Discharge Effects; 13) Internal Electrostatic Discharge--Satellite Killer; 14) Plasma Interactions DS-1 Ion Engines; 15) Radiation Effects on Spacecraft Systems and Materials; 16) Total Ionizing Dose Effects Total Ionizing Dose Effects; 17) Man-Made Sources of Space Effects Man-Made Sources of Space Effects; and 18) Space Environments Versus Interactions.

Zero-gravity cloud physics laboratory: Experiment program definition and preliminary laboratory concept studies

NASA Technical Reports Server (NTRS)

Eaton, L. R.; Greco, E. V.

1973-01-01

The experiment program definition and preliminary laboratory concept studies on the zero G cloud physics laboratory are reported. This program involves the definition and development of an atmospheric cloud physics laboratory and the selection and delineations of a set of candidate experiments that must utilize the unique environment of zero gravity or near zero gravity.

Adverse Health Effects Associated with Living in a Former Methamphetamine Drug Laboratory - Victoria, Australia, 2015.

PubMed

Wright, Jackie; Kenneally, Michaela E; Edwards, John W; Walker, G Stewart

2017-01-06

The manufacture of methamphetamine in clandestine drug laboratories occurs in various locations, including residential houses and apartments. Unlike the controlled manufacture of chemicals and drugs, clandestine manufacture results in the uncontrolled storage, use, generation, and disposal of a wide range of chemicals and the deposit of methamphetamine drug residues on indoor surfaces (1). These residues have been found at high levels on porous and nonporous surfaces and have been shown to persist for months to years (1). Persons exposed to these environments often have poorly defined exposures and health effects. It is commonly assumed that these levels of exposure are low compared with those related to illicit drug use or therapeutic use of amphetamine-based drugs for managing behavioral issues such as attention deficit hyperactivity disorder (2). In 2015, a family that was unknowingly exposed to methamphetamine residues in a house in Australia was found to have adverse health effects and elevated methamphetamine levels in hair samples, highlighting the potential for public health risks for persons who might live in methamphetamine-contaminated dwellings. This case study highlights the importance of the identification and effective decontamination of former clandestine drug laboratories.

The relationship between internet-gaming experience and executive functions measured by virtual environment compared with conventional laboratory multitasks.

PubMed

Chen, Yong-Quan; Hsieh, Shulan

2018-01-01

The aim of this study was to investigate if individuals with frequent internet gaming (IG) experience exhibited better or worse multitasking ability compared with those with infrequent IG experience. The individuals' multitasking abilities were measured using virtual environment multitasks, such as Edinburgh Virtual Errands Test (EVET), and conventional laboratory multitasks, such as the dual task and task switching. Seventy-two young healthy college students participated in this study. They were split into two groups based on the time spent on playing online games, as evaluated using the Internet Use Questionnaire. Each participant performed EVET, dual-task, and task-switching paradigms on a computer. The current results showed that the frequent IG group performed better on EVET compared with the infrequent IG group, but their performance on the dual-task and task-switching paradigms did not differ significantly. The results suggest that the frequent IG group exhibited better multitasking efficacy if measured using a more ecologically valid task, but not when measured using a conventional laboratory multitasking task. The differences in terms of the subcomponents of executive function measured by these task paradigms were discussed. The current results show the importance of the task effect while evaluating frequent internet gamers' multitasking ability.

The relationship between internet-gaming experience and executive functions measured by virtual environment compared with conventional laboratory multitasks

PubMed Central

Chen, Yong-Quan

2018-01-01

The aim of this study was to investigate if individuals with frequent internet gaming (IG) experience exhibited better or worse multitasking ability compared with those with infrequent IG experience. The individuals’ multitasking abilities were measured using virtual environment multitasks, such as Edinburgh Virtual Errands Test (EVET), and conventional laboratory multitasks, such as the dual task and task switching. Seventy-two young healthy college students participated in this study. They were split into two groups based on the time spent on playing online games, as evaluated using the Internet Use Questionnaire. Each participant performed EVET, dual-task, and task-switching paradigms on a computer. The current results showed that the frequent IG group performed better on EVET compared with the infrequent IG group, but their performance on the dual-task and task-switching paradigms did not differ significantly. The results suggest that the frequent IG group exhibited better multitasking efficacy if measured using a more ecologically valid task, but not when measured using a conventional laboratory multitasking task. The differences in terms of the subcomponents of executive function measured by these task paradigms were discussed. The current results show the importance of the task effect while evaluating frequent internet gamers’ multitasking ability. PMID:29879150

Tiger Team Assessment of the Ames Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-03-01

This report documents the Tiger Assessment of the Ames Laboratory (Ames), located in Ames, Iowa. Ames is operated for the US Department of Energy (DOE) by Iowa State University. The assessment was conducted from February 10 to March 5, 1992, under the auspices of the Office of Special Projects, Office of the Assistant Secretary of Environment, Safety and Health, Headquarters, DOE. The assessment was comprehensive, encompassing Environment, Safety, and Health (ES H) disciplines; management practices; and contractor and DOE self-assessments. Compliance with applicable Federal, State of Iowa, and local regulations; applicable DOE Orders; best management practices; and internal requirements atmore » Ames Laboratory were assessed. In addition, an evaluation of the adequacy and effectiveness of DOE and the site contractor's management of ES H/quality assurance program was conducted.« less

Laboratory Impact Experiments

NASA Astrophysics Data System (ADS)

Horanyi, M.; Munsat, T.

2017-12-01

The experimental and theoretical programs at the SSERVI Institute for Modeling Plasmas, Atmospheres, and Cosmic Dust (IMPACT) address the effects of hypervelocity dust impacts and the nature of the space environment of granular surfaces interacting with solar wind plasma and ultraviolet radiation. These are recognized as fundamental planetary processes due their role in shaping the surfaces of airless planetary objects, their plasma environments, maintaining dust haloes, and sustaining surface bound exospheres. Dust impacts are critically important for all airless bodies considered for possible human missions in the next decade: the Moon, Near Earth Asteroids (NEAs), Phobos, and Deimos, with direct relevance to crew and mission safety and our ability to explore these objects. This talk will describe our newly developed laboratory capabilities to assess the effects of hypervelocity dust impacts on: 1) the gardening and redistribution of dust particles; and 2) the generation of ionized and neutral gasses on the surfaces of airless planetary bodies.

Features of an effective operative dentistry learning environment: students' perceptions and relationship with performance.

PubMed

Suksudaj, N; Lekkas, D; Kaidonis, J; Townsend, G C; Winning, T A

2015-02-01

Students' perceptions of their learning environment influence the quality of outcomes they achieve. Learning dental operative techniques in a simulated clinic environment is characterised by reciprocal interactions between skills training, staff- and student-related factors. However, few studies have examined how students perceive their operative learning environments and whether there is a relationship between their perceptions and subsequent performance. Therefore, this study aimed to clarify which learning activities and interactions students perceived as supporting their operative skills learning and to examine relationships with their outcomes. Longitudinal data about examples of operative laboratory sessions that were perceived as effective or ineffective for learning were collected twice a semester, using written critical incidents and interviews. Emergent themes from these data were identified using thematic analysis. Associations between perceptions of learning effectiveness and performance were analysed using chi-square tests. Students indicated that an effective learning environment involved interactions with tutors and peers. This included tutors arranging group discussions to clarify processes and outcomes, providing demonstrations and constructive feedback. Feedback focused on mistakes, and not improvement, was reported as being ineffective for learning. However, there was no significant association between students' perceptions of the effectiveness of their learning experiences and subsequent performance. It was clear that learning in an operative technique setting involved various factors related not only to social interactions and observational aspects of learning but also to cognitive, motivational and affective processes. Consistent with studies that have demonstrated complex interactions between students, their learning environment and outcomes, other factors need investigation. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

An examination of speech reception thresholds measured in a simulated reverberant cafeteria environment.

PubMed

Best, Virginia; Keidser, Gitte; Buchholz, Jörg M; Freeston, Katrina

2015-01-01

There is increasing demand in the hearing research community for the creation of laboratory environments that better simulate challenging real-world listening environments. The hope is that the use of such environments for testing will lead to more meaningful assessments of listening ability, and better predictions about the performance of hearing devices. Here we present one approach for simulating a complex acoustic environment in the laboratory, and investigate the effect of transplanting a speech test into such an environment. Speech reception thresholds were measured in a simulated reverberant cafeteria, and in a more typical anechoic laboratory environment containing background speech babble. The participants were 46 listeners varying in age and hearing levels, including 25 hearing-aid wearers who were tested with and without their hearing aids. Reliable SRTs were obtained in the complex environment, but led to different estimates of performance and hearing-aid benefit from those measured in the standard environment. The findings provide a starting point for future efforts to increase the real-world relevance of laboratory-based speech tests.

An examination of speech reception thresholds measured in a simulated reverberant cafeteria environment

PubMed Central

Best, Virginia; Keidser, Gitte; Buchholz, J(x004E7)rg M.; Freeston, Katrina

2016-01-01

Objective There is increasing demand in the hearing research community for the creation of laboratory environments that better simulate challenging real-world listening environments. The hope is that the use of such environments for testing will lead to more meaningful assessments of listening ability, and better predictions about the performance of hearing devices. Here we present one approach for simulating a complex acoustic environment in the laboratory, and investigate the effect of transplanting a speech test into such an environment. Design Speech reception thresholds were measured in a simulated reverberant cafeteria, and in a more typical anechoic laboratory environment containing background speech babble. Study Sample The participants were 46 listeners varying in age and hearing levels, including 25 hearing-aid wearers who were tested with and without their hearing aids. Results Reliable SRTs were obtained in the complex environment, but led to different estimates of performance and hearing aid benefit from those measured in the standard environment. Conclusions The findings provide a starting point for future efforts to increase the real-world relevance of laboratory-based speech tests. PMID:25853616

Using Technology to Enhance the Effectiveness of General Chemistry Laboratory Courses

ERIC Educational Resources Information Center

Carvalho-Knighton, Kathleen M.; Keen-Rocha, Linda

2007-01-01

The effectiveness of two different laboratory techniques is compared to teach students majoring in science in a general chemistry laboratory. The results demonstrated that student laboratory activities with computer-interface systems could improve student understanding.

Laboratory exercises, remote sensing of the environment

NASA Technical Reports Server (NTRS)

Mintzer, O.; Ray, J.

1981-01-01

The exercises are designed to convey principles and theory of remote sensing, and methodologies of its application to civil engineering and environmental concerns, including agronomy, geography, geology, wildlife, forestry, hydrology, and other related fields. During the exercises the student is introduced to several types of remote sensing represented by imagery from conventional format: panchromatic, black-and-white infrared, color, and infrared, 35mm aerial photography, thermal infrared, radar, multispectral scanner, and LANDSAT. Upon completion of the exercises the student is expected to know: (1) the electromagnetic spectrum, its various wavelength sub-sections and their uses as sensors, (2) the limitations of each sensor, (3) the interpretation techniques used for extracting data from the various types of imagery, and (4) the cost effectiveness of remote sensing procedures for acquiring and evaluating data of the natural environment.

Taking Science Online: Evaluating Presence and Immersion through a Laboratory Experience in a Virtual Learning Environment for Entomology Students

ERIC Educational Resources Information Center

Annetta, Leonard; Klesath, Marta; Meyer, John

2009-01-01

A 3-D virtual field trip was integrated into an online college entomology course and developed as a trial for the possible incorporation of future virtual environments to supplement online higher education laboratories. This article provides an explanation of the rationale behind creating the virtual experience, the Bug Farm; the method and…

Effects of Students' Pre- and Post-Laboratory Concept Maps on Students' Attitudes toward Chemistry Laboratory in University General Chemistry

ERIC Educational Resources Information Center

Kilic, Ziya; Kaya, Osman Nafiz; Dogan, Alev

2004-01-01

The purpose of this study was to investigate the effects of scientific discussions based on student-constructed pre- and post-laboratory concept maps on students' attitudes toward chemistry laboratory in the university general chemistry. As part of instruction, during the first four laboratory sessions, students were taught how to construct and…

Survival of Escherichia coli with and without ColE1::Tn5 after aerosol dispersal in a laboratory and a farm environment.

PubMed Central

Marshall, B; Flynn, P; Kamely, D; Levy, S B

1988-01-01

The survival of a laboratory strain and a naturally occurring fecal strain of Escherichia coli, with and without a Tn5-containing derivative of ColE1, was examined after aerosol dispersal in a laboratory office and a barn under ambient temperature and humidity conditions. Following the release of paired strains, air and diverse types of surfaces were assayed for the test organisms. In both environments, the number of airborne bacteria declined rapidly within the first 2 h. Longer survival was found on surfaces and varied with surface type: recovery was greatest from wood products. Organisms persisted for 1 day in the office and for up to 20 days in the barn. Survival of the fecal strain was better than that of the laboratory strain in both test environments. In general, plasmid-bearing strains fared similarly to their plasmidless parents, but in several comparisons the ColE1::Tn5-containing strain showed enhanced survival. These studies have implications for the present and proposed release of genetically engineered organisms with and without plasmid vectors. PMID:2843099

Effects of service environments on aluminum-brazed titanium (ABTi)

NASA Technical Reports Server (NTRS)

Cotton, W. L.

1978-01-01

Aluminum brazed titanium (ABTi) structures were evaluated during prolonged exposure to extreme environments: elevated temperature exposure to airline service fluids, hydraulic fluid, and seawater, followed by laboratory corrosion tests. Solid-face and perforated face honeycomb sandwich panel specimens, stressed panel assemblies, and faying surface brazed joints were tested. The corrosion resistance of ABTi is satisfactory for commercial airline service. Unprotected ABTi proved inherently resistant to attack by all of the extreme service aircraft environments except: seawater at 700 K (800 F) and above, dripping phosphate ester hydraulic fluid at 505 K (450 F), and a marine environment at ambient temperature. The natural oxides and deposits present on titanium surfaces in airline service provide protection against hot salt corrosion pitting. Coatings are required to protect titanium dripping phosphate ester fluid at elevated temperatures and to protect exposed acoustic honeycomb parts against corrosion in a marine environment.

Purple Computational Environment With Mappings to ACE Requirements for the General Availability User Environment Capabilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barney, B; Shuler, J

2006-08-21

Purple is an Advanced Simulation and Computing (ASC) funded massively parallel supercomputer located at Lawrence Livermore National Laboratory (LLNL). The Purple Computational Environment documents the capabilities and the environment provided for the FY06 LLNL Level 1 General Availability Milestone. This document describes specific capabilities, tools, and procedures to support both local and remote users. The model is focused on the needs of the ASC user working in the secure computing environments at Los Alamos National Laboratory, Lawrence Livermore National Laboratory, and Sandia National Laboratories, but also documents needs of the LLNL and Alliance users working in the unclassified environment. Additionally,more » the Purple Computational Environment maps the provided capabilities to the Trilab ASC Computing Environment (ACE) Version 8.0 requirements. The ACE requirements reflect the high performance computing requirements for the General Availability user environment capabilities of the ASC community. Appendix A lists these requirements and includes a description of ACE requirements met and those requirements that are not met for each section of this document. The Purple Computing Environment, along with the ACE mappings, has been issued and reviewed throughout the Tri-lab community.« less

Effects of light at night on laboratory animals and research outcomes.

PubMed

Emmer, Kathryn M; Russart, Kathryn L G; Walker, William H; Nelson, Randy J; DeVries, A Courtney

2018-06-28

Light has substantial influences on the physiology and behavior of most laboratory animals. As such, lighting conditions within animal rooms are potentially significant and often underappreciated variables within experiments. Disruption of the light/dark cycle, primarily by exposing animals to light at night (LAN), disturbs biological rhythms and has widespread physiological consequences because of mechanisms such as melatonin suppression, sympathetic stimulation, and altered circadian clock gene expression. Thus, attention to the lighting environment of laboratory animals and maintaining consistency of a light/dark cycle is imperative for study reproducibility. Light intensity, as well as wavelength, photoperiod, and timing, are all important variables. Although modern rodent facilities are designed to facilitate appropriate light cycling, there are simple ways to modify rooms to prevent extraneous light exposure during the dark period. Attention to lighting conditions of laboratory animals by both researchers and research care staff ensures best practices for maintaining animal welfare, as well as reproducibility of research results. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Changing needs, opportunities and constraints for the 21st century microbiology laboratory.

PubMed

Van Eldere, J

2005-04-01

Clinical microbiologists and microbiology laboratories are experiencing changes due to evolving views on 'healthcare delivery' as an economic activity, due to changes in the medical environment and the demographics of the workforce, and technical evolution. Cost-effectiveness of laboratory procedures has been achieved through consolidation and integration of laboratories. Consolidation offers economy of scale and reduction in numbers of on-site staff, but also leads to separation of microbiologists from their clinical colleagues. Integration puts different laboratory disciplines under a single management, and leads to reorganisation of laboratories along common work-lines. Cost-savings combined with on-site availability of laboratories are achieved at the expense of a reduction in the influence of microbiologists in the daily running of the laboratory. Medically, there is growing emphasis on evidence-based diagnostics. Because of time-delays inherent in culturing, microbiology through rapid testing is mandatory. There is an increasing shortage in Europe and the USA of trained microbiology laboratory technicians and microbiologists. This reinforces the trend towards more automation and integration. Technological advances, particularly in molecular diagnostics, offer the possibility of rapid reporting and improvement of the impact of clinical microbiology on patient management. Molecular tests, however, fit perfectly the concept of an integrated laboratory and may further loosen the link between microbiologist and microbiology tests. The challenge for clinical microbiology will be to use new techniques to improve its cost-effectiveness and impact on infectious disease management. The future organisation of microbiology laboratories must support this but is itself of secondary importance. The training of future microbiologist must prepare them for this changing environment.

Application of Emulsified Zero-Valent Iron to Marine Environments

NASA Technical Reports Server (NTRS)

Brooks, Kathleen B.; Quinn, Jacqueline W.; Clausen, Christian A.; Geiger, Cherie L.

2005-01-01

Contamination of marine waters and sediments with heavy metals and dense non-aqueous phase liquids (DNAPLs) including chlorinated solvents, pesticides and PCBs pose ecological and human health risks through the contaminant's potential bioaccumulation in fish, shellfish and avian populations. The contaminants enter marine environments through improper disposal techniques and storm water run-off. Current remediation technologies for application to marine environments include costly dredging and off-site treatment of the contaminated media. Emulsified zero-valent iron (EZVI) has been proven to effectively degrade dissolved-phase and DNAPL-phase contaminants in freshwater environments on both the laboratory and field-scale level. However, the application to marine environments is only just being explored. This paper discusses the potential use of EZVI in brackish and saltwater environments, with supporting laboratory data detailed. Laboratory studies were performed in 2005 to establish the effectiveness of EZVI to degrade trichloroethylene (TCE) in saltwater. Headspace vials were setup to determine the kinetic rate of TCE degradation using EZVI in seawater. The reaction vials were analyzed by Gas Chromatographic/Flame Ionization Detection (GC/FID) for ethene production after a 48 day period using a GC/FID Purge and Trap system. Analytical results showed that EZVI was very effective at degrading TCE. The reaction by-products (ethene, acetylene and ethane) were produced at 71% of the rate in seawater as in the fresh water controls. Additionally, iron within the EZVI particles was protected from oxidation of the corrosive seawater, allowing EZVI to perform in an environment where zero-valent iron alone could not compete. Laboratory studies were also performed to establish the effectiveness of emulsified zero-valent metal (EZVM) to remove dissolved-phase cadmium and lead found in seawater. EZVM is comprised of a combination of magnesium and iron metal surrounded by the

NASA's Space Environments and Effects (SEE) Program

NASA Technical Reports Server (NTRS)

Minor, Jody

2001-01-01

The return of the Long Duration Exposure Facility (LDEF) in 1990 brought a wealth of space exposure data on materials, paints, solar cells, adhesives and other data on the many space environments. The effects of the harsh space environments can provide damaging or even disabling effects on a spacecraft, its sub-systems, materials and instruments. In partnership with industry, academia, and other US and international government agencies, the National Aeronautics & Space Administration's (NASA's) Space Environments & Effects (SEE) Program defines the space environments and provides technology development to accommodate or mitigate these harmful environments on the spacecraft. This program (agency-wide in scope but managed at the Marshall Space Flight Center) provides a very comprehensive and focused approach to understanding the space environment. It does this by defining the best techniques for both flight- and groundbased experimentation, updating models which predict both the environments and the environmental effects on spacecraft and ensuring that this information is properly maintained and inserted into spacecraft design programs. This paper will describe the current SEE Program and discuss several current technology development activities associated with the spacecraft charging phenomenon.

Virtual Laboratory "vs." Traditional Laboratory: Which Is More Effective for Teaching Electrochemistry?

ERIC Educational Resources Information Center

Hawkins, Ian; Phelps, Amy J.

2013-01-01

The use of virtual laboratories has become an increasing issue regarding science laboratories due to the increasing cost of hands-on laboratories, and the increase in distance education. Recent studies have looked at the use of virtual tools for laboratory to be used as supplements to the regular hands-on laboratories but many virtual tools have…

Acceleration Environment of the International Space Station

NASA Technical Reports Server (NTRS)

McPherson, Kevin; Kelly, Eric; Keller, Jennifer

2009-01-01

Measurement of the microgravity acceleration environment on the International Space Station has been accomplished by two accelerometer systems since 2001. The Microgravity Acceleration Measurement System records the quasi-steady microgravity environment, including the influences of aerodynamic drag, vehicle rotation, and venting effects. Measurement of the vibratory/transient regime, comprised of vehicle, crew, and equipment disturbances, has been accomplished by the Space Acceleration Measurement System-II. Until the arrival of the Columbus Orbital Facility and the Japanese Experiment Module, the location of these sensors, and therefore, the measurement of the microgravity acceleration environment, has been limited to within the United States Laboratory. Japanese Aerospace Exploration Agency has developed a vibratory acceleration measurement system called the Microgravity Measurement Apparatus which will be deployed within the Japanese Experiment Module to make distributed measurements of the Japanese Experiment Module's vibratory acceleration environment. Two Space Acceleration Measurement System sensors from the United States Laboratory will be re-deployed to support vibratory acceleration data measurement within the Columbus Orbital Facility. The additional measurement opportunities resulting from the arrival of these new laboratories allows Principal Investigators with facilities located in these International Space Station research laboratories to obtain microgravity acceleration data in support of their sensitive experiments. The Principal Investigator Microgravity Services project, at NASA Glenn Research Center, in Cleveland, Ohio, has supported acceleration measurement systems and the microgravity scientific community through the processing, characterization, distribution, and archival of the microgravity acceleration data obtained from the International Space Station acceleration measurement systems. This paper summarizes the PIMS capabilities available

Fatigue and its Effect on Performance in Military Environments

DTIC Science & Technology

2007-01-01

orne and orne , 1985). operational environments share common characteristics such as long work hours, working conditions that vary from boring to...operations Desert Shield and Desert Storm (Interim No. NAMrL-1377). Pensacola, FL: Naval Aerospace Medical research Laboratory. Dinges, D.F., orne , K.T. and... orne , E.C. (1985) “Assessing Performance upon Abrupt Awakening from Naps during Quasi-Continuous operations”, Behavior Research Methods, Instruments

Biosafety principles and practices for the veterinary diagnostic laboratory.

PubMed

Kozlovac, Joseph; Schmitt, Beverly

2015-01-01

Good biosafety and biocontainment programs and practices are critical components of the successful operation of any veterinary diagnostic laboratory. In this chapter we provide information and guidance on critical biosafety management program elements, facility requirements, protective equipment, and procedures necessary to ensure that the laboratory worker and the environment are adequately protected in the challenging work environment of the veterinary diagnostic laboratory in general and provide specific guidance for those laboratories employing molecular diagnostic techniques.

40 CFR 792.49 - Laboratory operation areas.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 32 2011-07-01 2011-07-01 false Laboratory operation areas. 792.49... CONTROL ACT (CONTINUED) GOOD LABORATORY PRACTICE STANDARDS Facilities § 792.49 Laboratory operation areas. Separate laboratory space and other space shall be provided, as needed, for the performance of the routine...

Planetary stations and Abyssal Benthic Laboratories: An overview of parallel approaches for long-term investigation in extreme environments

NASA Technical Reports Server (NTRS)

Dipippo, S.; Prendin, W.; Gasparoni, F.

1994-01-01

In spite of the apparent great differences between deep ocean and space environment, significant similarities can be recognized when considering the possible solutions and technologies enabling the development of remote automatic stations supporting the execution of scientific activities. In this sense it is believed that mutual benefits shall be derived from the exchange of experiences and results between people and organizations involved in research and engineering activities for hostile environments, such as space, deep sea, and polar areas. A significant example of possible technology transfer and common systematic approach is given, which describes in some detail how the solutions and the enabling technologies identified for an Abyssal Benthic Laboratory can be applied for the case of a lunar or planetary station.

An overview of the U.S. Army Research Laboratory's Sensor Information Testbed for Collaborative Research Environment (SITCORE) and Automated Online Data Repository (AODR) capabilities

NASA Astrophysics Data System (ADS)

Ward, Dennis W.; Bennett, Kelly W.

2017-05-01

The Sensor Information Testbed COllaberative Research Environment (SITCORE) and the Automated Online Data Repository (AODR) are significant enablers of the U.S. Army Research Laboratory (ARL)'s Open Campus Initiative and together create a highly-collaborative research laboratory and testbed environment focused on sensor data and information fusion. SITCORE creates a virtual research development environment allowing collaboration from other locations, including DoD, industry, academia, and collation facilities. SITCORE combined with AODR provides end-toend algorithm development, experimentation, demonstration, and validation. The AODR enterprise allows the U.S. Army Research Laboratory (ARL), as well as other government organizations, industry, and academia to store and disseminate multiple intelligence (Multi-INT) datasets collected at field exercises and demonstrations, and to facilitate research and development (R and D), and advancement of analytical tools and algorithms supporting the Intelligence, Surveillance, and Reconnaissance (ISR) community. The AODR provides a potential central repository for standards compliant datasets to serve as the "go-to" location for lessons-learned and reference products. Many of the AODR datasets have associated ground truth and other metadata which provides a rich and robust data suite for researchers to develop, test, and refine their algorithms. Researchers download the test data to their own environments using a sophisticated web interface. The AODR allows researchers to request copies of stored datasets and for the government to process the requests and approvals in an automated fashion. Access to the AODR requires two-factor authentication in the form of a Common Access Card (CAC) or External Certificate Authority (ECA)

Laboratory Safety is Everyone's Responsibility.

ERIC Educational Resources Information Center

Brubaker, Inara M.; And Others

1981-01-01

Outlines a survey of laboratory practices and policies for employee protection from exposure to chemicals. Findings support the argument that academic, industrial, and other research laboratories are different from the manufacturing environment and should have a different toxic chemical policy and standards. (Author/SK)

Tethered gravity laboratories study

NASA Technical Reports Server (NTRS)

Lucchetti, F.

1990-01-01

The scope of the study is to investigate ways of controlling the microgravity environment of the International Space Station by means of a tethered system. Four main study tasks were performed. First, researchers analyzed the utilization of the tether systems to improve the lowest possible steady gravity level on the Space Station and the tether capability to actively control the center of gravity position in order to compensate for activities that would upset the mass distribution of the Station. The purpose of the second task was to evaluate the whole of the experiments performable in a variable gravity environment and the related beneficial residual accelerations, both for pure and applied research in the fields of fluid, materials, and life science, so as to assess the relevance of a variable g-level laboratory. The third task involves the Tethered Variable Gravity Laboratory. The use of the facility that would crawl along a deployed tether and expose experiments to varying intensities of reduced gravity is discussed. Last, a study performed on the Attitude Tether Stabilizer concept is discussed. The stabilization effect of ballast masses tethered to the Space Station was investigated as a means of assisting the attitude control system of the Station.

Investigating the Effect of Argument-Driven Inquiry in Laboratory Instruction

ERIC Educational Resources Information Center

Demircioglu, Tuba; Ucar, Sedat

2015-01-01

The aim of this study is to investigate the effect of argument-driven inquiry (ADI) based laboratory instruction on the academic achievement, argumentativeness, science process skills, and argumentation levels of pre-service science teachers in the General Physics Laboratory III class. The study was conducted with 79 pre-service science teachers.…

Historic Context and Building Assessments for the Lawrence Livermore National Laboratory Built Environment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ullrich, R. A.; Sullivan, M. A.

2007-09-14

This document was prepared to support u.s. Department of Energy / National Nuclear Security Agency (DOE/NNSA) compliance with Sections 106 and 110 of the National Historic Preservation Act (NHPA). Lawrence Livermore National Laboratory (LLNL) is a DOE/NNSA laboratory and is engaged in determining the historic status of its properties at both its main site in Livermore, California, and Site 300, its test site located eleven miles from the main site. LLNL contracted with the authors via Sandia National Laboratories (SNL) to prepare a historic context statement for properties at both sites and to provide assessments of those properties of potentialmore » historic interest. The report contains an extensive historic context statement and the assessments of individual properties and groups of properties determined, via criteria established in the context statement, to be of potential interest. The historic context statement addresses the four contexts within which LLNL falls: Local History, World War II History (WWII), Cold War History, and Post-Cold War History. Appropriate historic preservation themes relevant to LLNL's history are delineated within each context. In addition, thresholds are identified for historic significance within each of the contexts based on the explication and understanding of the Secretary of the Interior's Guidelines for determining eligibility for the National Register of Historic Places. The report identifies specific research areas and events in LLNL's history that are of interest and the portions of the built environment in which they occurred. Based on that discussion, properties of potential interest are identified and assessments of them are provided. Twenty individual buildings and three areas of potential historic interest were assessed. The final recommendation is that, of these, LLNL has five individual historic buildings, two sets of historic objects, and two historic districts eligible for the National Register. All are eligible

Near Field Observations of Seismicity in Volcanic Environments: A Read-Made Field Laboratory

NASA Astrophysics Data System (ADS)

Bean, C. J.; Thun, J.; Eibl, E. P. S.; Benson, P. M.; Rowley, P.; Lokmer, I.; Cauchie, L.

2017-12-01

Volcanic environments experience periods of rapid stress fluctuations and consequent seismicity. This volcano seismicity is diverse in character, spanning the range from discrete high frequency events through low-frequency earthquakes and tremor. The inter-relationships between these events appear to be controlled by edifice rheology, stress state and the presence of fluids (which help modulate the stress field). In general volcanoes are accessible to instrumentation, allowing near-field access to the seismicity at play. Here we present results from a range of field, numerical and laboratory experiments that demonstrate the controls that rheology and strain rate play on seismicity type. In particular we demonstrate the role played by internal friction angles on the initiation and evolution of seismicity, in dry weak-compliant volcanic materials. Furthermore we show the importance of near field observation in constraining details of the seismic source, in a meso-scale field setting.

The value-added laboratory: an opportunity to merge research and service objectives.

PubMed

McDonald, J M

1997-01-01

The changing health-care environment is creating a new opportunities for laboratory medicine professionals that correspond with the new health services research agendas. Proving cost-effectiveness and conducting outcomes assessment are becoming vital functions of laboratories in this era of managed care. Laboratorians must take advantage of the resulting opportunities to show how they add value and medical relevance to the health-care delivery system.

Effects of the chemical environment on the spectroscopic properties of clays: Applications for Mars

NASA Technical Reports Server (NTRS)

Bishop, Janice L.; Pieters, Carle M.

1992-01-01

Laboratory studies of Mars soil analogs pose unique problems, since soils interact readily with their environment and exhibit variable characteristics depending on the environment. We have performed a series of experiments focusing on the spectral properties of clays and how they vary as a function of composition and environment, including examination of fundamental as well as overtone absorptions, that occur in the mid- and near-IR, respectively. Smectite clays have been selected in our laboratory experiments as a primary surface analog for Mars because of their compatibility with results of the Viking biology experiments, their stability under current martian conditions, and their compatibility with reflectance spectra of Mars. We prepared a number of monoionic montmorillonites in order to examine the influence of cations on the water molecules in the clay interlayer region. Moessbauer spectra of several montmorillonites with variable amounts of interlayer iron confirm the presence of ferrihydrite.

Quality and safety aspects in histopathology laboratory

PubMed Central

Adyanthaya, Soniya; Jose, Maji

2013-01-01

Histopathology is an art of analyzing and interpreting the shapes, sizes and architectural patterns of cells and tissues within a given specific clinical background and a science by which the image is placed in the context of knowledge of pathobiology, to arrive at an accurate diagnosis. To function effectively and safely, all the procedures and activities of histopathology laboratory should be evaluated and monitored accurately. In histopathology laboratory, the concept of quality control is applicable to pre-analytical, analytical and post-analytical activities. Ensuring safety of working personnel as well as environment is also highly important. Safety issues that may come up in a histopathology lab are primarily those related to potentially hazardous chemicals, biohazardous materials, accidents linked to the equipment and instrumentation employed and general risks from electrical and fire hazards. This article discusses quality management system which can ensure quality performance in histopathology laboratory. The hazards in pathology laboratories and practical safety measures aimed at controlling the dangers are also discussed with the objective of promoting safety consciousness and the practice of laboratory safety. PMID:24574660

Galactic Neighborhood and Laboratory Astrophysics

NASA Astrophysics Data System (ADS)

Wang, Q. D.

2011-05-01

The galactic neighborhood, extending from the Milky Way to redshifts of about 0.1, is our unique local laboratory for detailed study of galaxies and their interplay with the environment. Such study provides a foundation of knowledge for interpreting observations of more distant galaxies and their environment. The Astro 2010 Science Frontier Galactic Neighborhood Panel identified four key sci- entific questions: 1) What are the flows of matter and energy in the circumgalac- tic medium? 2) What controls the mass-energy-chemical cycles within galaxies? 3) What is the fossil record of galaxy assembly from first stars to present? 4) What are the connections between dark and luminous matter? These questions, essential to the understanding of galaxies as interconnected complexes, can be addressed most effectively and/or uniquely in the galactic neighborhood. The panel also highlighted the discovery potential of time-domain astronomy and astrometry with powerful new techniques and facilities to greatly advance our understanding of the precise connections among stars, galaxies, and newly dis- covered transient events. The relevant needs for laboratory astrophysics will be emphasized, especially in the context of supporting NASA missions.

Radiation Environment Effects on Spacecraft

NASA Technical Reports Server (NTRS)

Ladbury, Ray.

2017-01-01

Space poses a variety of radiation hazards. These hazards pose different risks for different missions depending on the mission environment, duration and requirements. This presentation presents a brief look at several radiation related hazards, including destructive and nondestructive Single-Event Effect, Total Ionizing Dose, Displacement Damage and Spacecraft Charging. The temporal and spatial characteristics for the environments of concern for each are considered.

A cold-adapted reptile becomes a more effective thermoregulator in a thermally challenging environment.

PubMed

Besson, Anne Amélie; Cree, Alison

2010-07-01

Thermoregulation is of great importance for the survival and fitness of ectotherms as physiological functions are optimized within a narrow range of body temperature (T(b)). The precision with which reptiles thermoregulate has been proposed to be related to the thermal quality of their environments. Although a number of studies have looked at the effect of thermal constraints imposed by diel, seasonal and altitudinal variation on thermoregulatory strategies, few have addressed this question in a laboratory setting. We conducted a laboratory experiment to test whether tuatara, Sphenodon punctatus (order Rhynchocephalia), a cold-adapted reptile endemic to New Zealand, modify their thermoregulatory behaviour in response to different thermal environments. We provided tuatara with three thermal treatments: high-quality habitat [preferred T(b) (T(sel)) could be reached for 8 h/day], medium-quality habitat (T(sel) available for 5 h/day) and low-quality habitat (T(sel) available for 3 h/day). All groups maintained body mass, but tuatara in the low-quality habitat thermoregulated more accurately and tended to maintain higher T (b)s than tuatara in the high-quality habitat. This study thus provides experimental evidence that reptiles are capable of adjusting their thermoregulatory behaviour in response to different thermal constraints. This result also has implications for the conservation of tuatara. A proposed translocation from their current habitat to a higher latitudinal range within New Zealand (similar to the shift from our 8 h/day to our 5 h/day regime) is unlikely to induce thermoconformity; rather, tuatara will probably engage in more effective thermoregulatory behaviour.

Chemical Understanding and Graphing Skills in an Honors Case-Based Computerized Chemistry Laboratory Environment: The Value of Bidirectional Visual and Textual Representations

ERIC Educational Resources Information Center

Dori, Yehudit J.; Sasson, Irit

2008-01-01

The case-based computerized laboratory (CCL) is a chemistry learning environment that integrates computerized experiments with emphasis on scientific inquiry and comprehension of case studies. The research objective was to investigate chemical understanding and graphing skills of high school honors students via bidirectional visual and textual…

HEW to Set Laboratory Safety Standards.

ERIC Educational Resources Information Center

Chemical and Engineering News, 1978

1978-01-01

Describes Department of Health, Education and Welfare (HEW) proposed guidelines for laboratories using chemical carcinogens. The guidelines are designed to provide protection for laboratory workers and their environment from exposure to all types of carcinogenic agents. (GA)

Space Environments and Spacecraft Effects Organization Concept

NASA Technical Reports Server (NTRS)

Edwards, David L.; Burns, Howard D.; Miller, Sharon K.; Porter, Ron; Schneider, Todd A.; Spann, James F.; Xapsos, Michael

2012-01-01

The National Aeronautics and Space Administration (NASA) is embarking on a course to expand human presence beyond Low Earth Orbit (LEO) while also expanding its mission to explore the solar system. Destinations such as Near Earth Asteroids (NEA), Mars and its moons, and the outer planets are but a few of the mission targets. Each new destination presents an opportunity to increase our knowledge of the solar system and the unique environments for each mission target. NASA has multiple technical and science discipline areas specializing in specific space environments disciplines that will help serve to enable these missions. To complement these existing discipline areas, a concept is presented focusing on the development of a space environments and spacecraft effects (SENSE) organization. This SENSE organization includes disciplines such as space climate, space weather, natural and induced space environments, effects on spacecraft materials and systems and the transition of research information into application. This space environment and spacecraft effects organization will be composed of Technical Working Groups (TWG). These technical working groups will survey customers and users, generate products, and provide knowledge supporting four functional areas: design environments, engineering effects, operational support, and programmatic support. The four functional areas align with phases in the program mission lifecycle and are briefly described below. Design environments are used primarily in the mission concept and design phases of a program. Engineering effects focuses on the material, component, sub-system and system-level selection and the testing to verify design and operational performance. Operational support provides products based on real time or near real time space weather to mission operators to aid in real time and near-term decision-making. The programmatic support function maintains an interface with the numerous programs within NASA, other federal

Evaluation of cost-effective sol-gel-based sensor for monitoring of formaldehyde in workplace environment and cancer risk assessment.

PubMed

Bunkoed, Opas; Thavarungkul, Panote; Thammakhet, Chongdee; Kanatharana, Proespichaya

2013-01-01

Formaldehyde was monitored in the workplace environment of an adhesive manufacturer producing formaldehyde and urea-formaldehyde resin using a cost-effective sol-gel-based sensor. The sensor was first evaluated by comparing its performance to the conventional 2,4-dinitrophynylhydrazine-devivatization method (2,4-DNPH) followed by high-performance liquid chromatography coupled to a UV detector. The formaldehyde concentrations obtained by both techniques were not significantly different. The cost-effective sol-gel-based sensor was then used for monitoring formaldehyde levels in the laboratories, production areas and storage room. Formaldehyde concentrations in this adhesive manufacturer workplace environment were lower than the limit value of, 0.75 ppm for an 8-h time weight average and 2 ppm for a short-term exposure (15 min). However, the cancer risk for employees who worked in the laboratories, (1.7±0.7)×10(-4)-(5±2)×10(-4), were higher than the acceptable cancer risk recommended by the US EPA (10(-6)). Therefore, some precaution should be taken to reduce the risk, such as an increase of ventilation to dilute the levels of formaldehyde and use air cleaners to remove formaldehyde.

Scientific Assistant Virtual Laboratory (SAVL)

NASA Astrophysics Data System (ADS)

Alaghband, Gita; Fardi, Hamid; Gnabasik, David

2007-03-01

The Scientific Assistant Virtual Laboratory (SAVL) is a scientific discovery environment, an interactive simulated virtual laboratory, for learning physics and mathematics. The purpose of this computer-assisted intervention is to improve middle and high school student interest, insight and scores in physics and mathematics. SAVL develops scientific and mathematical imagination in a visual, symbolic, and experimental simulation environment. It directly addresses the issues of scientific and technological competency by providing critical thinking training through integrated modules. This on-going research provides a virtual laboratory environment in which the student directs the building of the experiment rather than observing a packaged simulation. SAVL: * Engages the persistent interest of young minds in physics and math by visually linking simulation objects and events with mathematical relations. * Teaches integrated concepts by the hands-on exploration and focused visualization of classic physics experiments within software. * Systematically and uniformly assesses and scores students by their ability to answer their own questions within the context of a Master Question Network. We will demonstrate how the Master Question Network uses polymorphic interfaces and C# lambda expressions to manage simulation objects.

Effects of social isolation and environmental enrichment on laboratory housed pigs

USDA-ARS?s Scientific Manuscript database

The pig is becoming an increasingly important laboratory animal species. However, a laboratory setting often requires individual and sterile housing, which may impose stress. The objective of this study was to determine physiological, haematological and behavioral effects of isolation and environmen...

Workshop on the Space Environment: The Effects on the Optical Properties of Airless Bodies

NASA Technical Reports Server (NTRS)

Hapke, B. (Editor); Clark, B. (Editor); Benedix, G. (Editor); Domingue, D. (Editor); Cintala, M. (Editor)

1993-01-01

Reflectance spectrophotometry and polarimetry are major tools in remote sensing studies of surfaces of solar system bodies. The interpretations of such measurements are often based on laboratory studies of meteoritic, lunar, and terrestrial materials. However, the optical properties of regoliths are known to be affected by the space environment. Thus, some of the major questions addressed in the workshop include identity of the soil component responsible for alteration of the optical properties, the process that produced this component, and how reliably the effects of these processes could be extrapolated to other bodies of the solar system.

Implementing a Quality Management System in the Medical Microbiology Laboratory.

PubMed

Carey, Roberta B; Bhattacharyya, Sanjib; Kehl, Sue C; Matukas, Larissa M; Pentella, Michael A; Salfinger, Max; Schuetz, Audrey N

2018-07-01

This document outlines a comprehensive practical approach to a laboratory quality management system (QMS) by describing how to operationalize the management and technical requirements described in the ISO 15189 international standard. It provides a crosswalk of the ISO requirements for quality and competence for medical laboratories to the 12 quality system essentials delineated by the Clinical and Laboratory Standards Institute. The quality principles are organized under three main categories: quality infrastructure, laboratory operations, and quality assurance and continual improvement. The roles and responsibilities to establish and sustain a QMS are outlined for microbiology laboratory staff, laboratory management personnel, and the institution's leadership. Examples and forms are included to assist in the real-world implementation of this system and to allow the adaptation of the system for each laboratory's unique environment. Errors and nonconforming events are acknowledged and embraced as an opportunity to improve the quality of the laboratory, a culture shift from blaming individuals. An effective QMS encourages "systems thinking" by providing a process to think globally of the effects of any type of change. Ultimately, a successful QMS is achieved when its principles are adopted as part of daily practice throughout the total testing process continuum. Copyright © 2018 American Society for Microbiology.

Modular laboratories--cost-effective and sustainable infrastructure for resource-limited settings.

PubMed

Bridges, Daniel J; Colborn, James; Chan, Adeline S T; Winters, Anna M; Dengala, Dereje; Fornadel, Christen M; Kosloff, Barry

2014-12-01

High-quality laboratory space to support basic science, clinical research projects, or health services is often severely lacking in the developing world. Moreover, the construction of suitable facilities using traditional methods is time-consuming, expensive, and challenging to implement. Three real world examples showing how shipping containers can be converted into modern laboratories are highlighted. These include use as an insectary, a molecular laboratory, and a BSL-3 containment laboratory. These modular conversions have a number of advantages over brick and mortar construction and provide a cost-effective and timely solution to offer high-quality, user-friendly laboratory space applicable within the developing world. © The American Society of Tropical Medicine and Hygiene.

Space environment effects (M0006)

NASA Technical Reports Server (NTRS)

Angelo, J. A., Jr.; Madonna, R. G.; Altadonna, L. P.; Dagostino, M. D.; Chang, J. Y.; Alfano, R. R.; Caplan, V. L.

1984-01-01

The effects of long term exposure to the near Earth space environment on advanced electrooptical and radiation sensor components were examined. The effect of long duration spaceflight on the germination rate of selected terrestrial plant seeds is observed in exobiological experiments.

Prediction of space shuttle fluctuating pressure environments, including rocket plume effects

NASA Technical Reports Server (NTRS)

Plotkin, K. J.; Robertson, J. E.

1973-01-01

Preliminary estimates of space shuttle fluctuating pressure environments have been made based on prediction techniques developed by Wyle Laboratories. Particular emphasis has been given to the transonic speed regime during launch of a parallel-burn space shuttle configuration. A baseline configuration consisting of a lightweight orbiter and monolithic SRB, together with a typical flight trajectory, have been used as models for the predictions. Critical fluctuating pressure environments are predicted at transonic Mach numbers. Comparisons between predicted environments and wind tunnel test results, in general, showed good agreement. Predicted one-third octave band spectra for the above environments were generally one of three types: (1) attached turbulent boundary layer spectra (typically high frequencies); (2) homogeneous separated flow and shock-free interference flow spectra (typically intermediate frequencies); and (3) shock-oscillation and shock-induced interference flow spectra (typically low frequencies). Predictions of plume induced separated flow environments were made. Only the SRB plumes are important, with fluctuating levels comparable to compression-corner induced separated flow shock oscillation.

Cielo Computational Environment Usage Model With Mappings to ACE Requirements for the General Availability User Environment Capabilities Release Version 1.1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vigil,Benny Manuel; Ballance, Robert; Haskell, Karen

Cielo is a massively parallel supercomputer funded by the DOE/NNSA Advanced Simulation and Computing (ASC) program, and operated by the Alliance for Computing at Extreme Scale (ACES), a partnership between Los Alamos National Laboratory (LANL) and Sandia National Laboratories (SNL). The primary Cielo compute platform is physically located at Los Alamos National Laboratory. This Cielo Computational Environment Usage Model documents the capabilities and the environment to be provided for the Q1 FY12 Level 2 Cielo Capability Computing (CCC) Platform Production Readiness Milestone. This document describes specific capabilities, tools, and procedures to support both local and remote users. The model ismore » focused on the needs of the ASC user working in the secure computing environments at Lawrence Livermore National Laboratory (LLNL), Los Alamos National Laboratory, or Sandia National Laboratories, but also addresses the needs of users working in the unclassified environment. The Cielo Computational Environment Usage Model maps the provided capabilities to the tri-Lab ASC Computing Environment (ACE) Version 8.0 requirements. The ACE requirements reflect the high performance computing requirements for the Production Readiness Milestone user environment capabilities of the ASC community. A description of ACE requirements met, and those requirements that are not met, are included in each section of this document. The Cielo Computing Environment, along with the ACE mappings, has been issued and reviewed throughout the tri-Lab community.« less

Laboratory Investigation of Space and Planetary Dust Grains

NASA Technical Reports Server (NTRS)

Spann, James

2005-01-01

Dust in space is ubiquitous and impacts diverse observed phenomena in various ways. Understanding the dominant mechanisms that control dust grain properties and its impact on surrounding environments is basic to improving our understanding observed processes at work in space. There is a substantial body of work on the theory and modeling of dust in space and dusty plasmas. To substantiate and validate theory and models, laboratory investigations and space borne observations have been conducted. Laboratory investigations are largely confined to an assembly of dust grains immersed in a plasma environment. Frequently the behaviors of these complex dusty plasmas in the laboratory have raised more questions than verified theories. Space borne observations have helped us characterize planetary environments. The complex behavior of dust grains in space indicates the need to understand the microphysics of individual grains immersed in a plasma or space environment.

Evaluating the effectiveness of a laboratory-based professional development program for science educators

NASA Astrophysics Data System (ADS)

Amolins, Michael Wayne

The development of effective science educators has been a long-standing goal of the American education system. Numerous studies have suggested a breadth of professional development programs that have sought to utilize constructivist principles in order to orchestrate movement toward student-led, inquiry-based instruction. Very few, however, have addressed a missing link between the modern scientific laboratory and the traditional science classroom. While several laboratory-based training programs have begun to emerge in recent years, the skills necessary to translate this information into the classroom are rarely addressed. The result is that participants are often left without an outlet or the confidence to integrate these into their lessons. The purpose of this study was to examine the effectiveness of a laboratory-based professional development program focused on classroom integration and reformed science teaching principles. This was measured by the ability to invigorate its seven participants in order to achieve higher levels of success and fulfillment in the classroom. These participants all taught at public high schools in South Dakota, including both rural and urban locations, and taught a variety of courses. Participants were selected for this study through their participation in the Sanford Research/USD Science Educator Research Fellowship Program. Through the use of previously collected data acquired by Sanford Research, this study attempted to detail the convergence of three assessments in order to demonstrate the growth and development of its participants. First, pre- and post-program surveys were completed in order to display the personal and professional growth of its participants. Second, pre- and post-program classroom observations employing the Reformed Teaching Observation Protocol allowed for the assessment of pedagogical modifications being integrated by each participant, as well as the success of such modifications in constructively

STRUCTURED LEARNING AND TRAINING ENVIRONMENTS--A PREPARATION LABORATORY FOR ADVANCED MAMMALIAN PHYSIOLOGY.

ERIC Educational Resources Information Center

FIEL, NICHOLAS J.; JOHNSTON, RAYMOND F.

A PREPARATION LABORATORY WAS DESIGNED TO FAMILIARIZE STUDENTS IN ADVANCED MAMMALIAN PHYSIOLOGY WITH LABORATORY SKILLS AND TECHNIQUES AND THUS SHORTEN THE TIME THEY SPEND IN SETTING UP ACTUAL EXPERIMENTS. THE LABORATORY LASTS 30 MINUTES, IS FLEXIBLE AND SIMPLE OF OPERATION, AND DOES NOT REQUIRE A PROFESSOR'S PRESENCE. THE BASIC TRAINING UNIT IS THE…

The effect of rearing environment on memory formation.

PubMed

Rothwell, Cailin M; Spencer, Gaynor E; Lukowiak, Ken

2018-05-22

Lymnaea stagnalis is a well-studied model system for determining how changes in the environment influence associative learning and memory formation. For example, some wild strains of L. stagnalis , collected from separate geographic locations, show superior memory-forming abilities compared with others. Here, we studied memory formation in two laboratory-bred L. stagnalis strains, derived from the same original population in The Netherlands. The two strains were reared in two different laboratories at the University of Calgary (C-strain) and at Brock University (B-strain) for many years and we found that they differed in their memory-forming ability. Specifically, the C-strain required only two training sessions to form long-term memory (LTM) whereas the B-strain required four sessions to form LTM. Additionally, the LTM formed by the B-strain persisted for a shorter amount of time than the memory formed by the C-strain. Thus, despite being derived from the same original population, the C- and B-strains have developed different memory-forming abilities. Next, we raised the two strains from embryos away from home (i.e. in the other laboratory) over two generations and assessed their memory-forming abilities. The B-strain reared and maintained at the University of Calgary demonstrated improved memory-forming ability within a single generation, while the C-strain reared at Brock University retained their normal LTM-forming ability across two subsequent generations. This suggests that local environmental factors may contribute to the behavioural divergence observed between these two laboratory-bred strains. © 2018. Published by The Company of Biologists Ltd.

Current evidence and future perspectives on the effective practice of patient-centered laboratory medicine.

PubMed

Hallworth, Mike J; Epner, Paul L; Ebert, Christoph; Fantz, Corinne R; Faye, Sherry A; Higgins, Trefor N; Kilpatrick, Eric S; Li, Wenzhe; Rana, S V; Vanstapel, Florent

2015-04-01

Systematic evidence of the contribution made by laboratory medicine to patient outcomes and the overall process of healthcare is difficult to find. An understanding of the value of laboratory medicine, how it can be determined, and the various factors that influence it is vital to ensuring that the service is provided and used optimally. This review summarizes existing evidence supporting the impact of laboratory medicine in healthcare and indicates the gaps in our understanding. It also identifies deficiencies in current utilization, suggests potential solutions, and offers a vision of a future in which laboratory medicine is used optimally to support patient care. To maximize the value of laboratory medicine, work is required in 5 areas: (a) improved utilization of existing and new tests; (b) definition of new roles for laboratory professionals that are focused on optimizing patient outcomes by adding value at all points of the diagnostic brain-to-brain cycle; (c) development of standardized protocols for prospective patient-centered studies of biomarker clinical effectiveness or extraanalytical process effectiveness; (d) benchmarking of existing and new tests in specified situations with commonly accepted measures of effectiveness; (e) agreed definition and validation of effectiveness measures and use of checklists for articles submitted for publication. Progress in these areas is essential if we are to demonstrate and enhance the value of laboratory medicine and prevent valuable information being lost in meaningless data. This requires effective collaboration with clinicians, and a determination to accept patient outcome and patient experience as the primary measure of laboratory effectiveness. © 2014 American Association for Clinical Chemistry.

The development of a strategy for the implementation of automation in a bioanalytical laboratory.

PubMed

Mole, D; Mason, R J; McDowall, R D

1993-03-01

Laboratory automation is equipment, instrumentation, software and techniques that are classified into four groups: instrument automation; communications; data to information conversion; and information management. This new definition is necessary to understand the role that automation can play in achieving the aims and objectives of a laboratory within its organization. To undertake automation projects effectively, a laboratory automation strategy is outlined which requires an intimate knowledge of an organization and the target environment to implement individual automation projects.

Sediment and erosion control laboratory facility expansion.

DOT National Transportation Integrated Search

2016-08-01

The Sediment and Erosion Control Laboratory (SEC Lab), formerly the Hydraulics, Sedimentation, and : Erosion Control Laboratory, is operated by the Texas A&M Transportation Institutes Environment and : Planning Program. Performance evaluation prog...

Lawrence Livermore National Laboratory Environmental Report 2012

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, Henry E.; Armstrong, Dave; Blake, Rick G.

Lawrence Livermore National Laboratory (LLNL) is a premier research laboratory that is part of the National Nuclear Security Administration (NNSA) within the U.S. Department of Energy (DOE). As a national security laboratory, LLNL is responsible for ensuring that the nation’s nuclear weapons remain safe, secure, and reliable. The Laboratory also meets other pressing national security needs, including countering the proliferation of weapons of mass destruction and strengthening homeland security, and conducting major research in atmospheric, earth, and energy sciences; bioscience and biotechnology; and engineering, basic science, and advanced technology. The Laboratory is managed and operated by Lawrence Livermore National Security,more » LLC (LLNS), and serves as a scientific resource to the U.S. government and a partner to industry and academia. LLNL operations have the potential to release a variety of constituents into the environment via atmospheric, surface water, and groundwater pathways. Some of the constituents, such as particles from diesel engines, are common at many types of facilities while others, such as radionuclides, are unique to research facilities like LLNL. All releases are highly regulated and carefully monitored. LLNL strives to maintain a safe, secure and efficient operational environment for its employees and neighboring communities. Experts in environment, safety and health (ES&H) support all Laboratory activities. LLNL’s radiological control program ensures that radiological exposures and releases are reduced to as low as reasonably achievable to protect the health and safety of its employees, contractors, the public, and the environment. LLNL is committed to enhancing its environmental stewardship and managing the impacts its operations may have on the environment through a formal Environmental Management System. The Laboratory encourages the public to participate in matters related to the Laboratory’s environmental impact on the

Lawrence Livermore National Laboratory Environmental Report 2013

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, H. E.; Bertoldo, N. A.; Blake, R. G.

Lawrence Livermore National Laboratory (LLNL) is a premier research laboratory that is part of the National Nuclear Security Administration (NNSA) within the U.S. Department of Energy (DOE). As a national security laboratory, LLNL is responsible for ensuring that the nation’s nuclear weapons remain safe, secure, and reliable. The Laboratory also meets other pressing national security needs, including countering the proliferation of weapons of mass destruction and strengthening homeland security, and conducting major research in atmospheric, earth, and energy sciences; bioscience and biotechnology; and engineering, basic science, and advanced technology. The Laboratory is managed and operated by Lawrence Livermore National Security,more » LLC (LLNS), and serves as a scientific resource to the U.S. government and a partner to industry and academia. LLNL operations have the potential to release a variety of constituents into the environment via atmospheric, surface water, and groundwater pathways. Some of the constituents, such as particles from diesel engines, are common at many types of facilities while others, such as radionuclides, are unique to research facilities like LLNL. All releases are highly regulated and carefully monitored. LLNL strives to maintain a safe, secure and efficient operational environment for its employees and neighboring communities. Experts in environment, safety and health (ES&H) support all Laboratory activities. LLNL’s radiological control program ensures that radiological exposures and releases are reduced to as low as reasonably achievable to protect the health and safety of its employees, contractors, the public, and the environment. LLNL is committed to enhancing its environmental stewardship and managing the impacts its operations may have on the environment through a formal Environmental Management System. The Laboratory encourages the public to participate in matters related to the Laboratory’s environmental impact on the

Designing Experiments on Thermal Interactions by Secondary-School Students in a Simulated Laboratory Environment

ERIC Educational Resources Information Center

Lefkos, Ioannis; Psillos, Dimitris; Hatzikraniotis, Euripides

2011-01-01

Background and purpose: The aim of this study was to explore the effect of investigative activities with manipulations in a virtual laboratory on students' ability to design experiments. Sample: Fourteen students in a lower secondary school in Greece attended a teaching sequence on thermal phenomena based on the use of information and…

Does the Lack of Hands-On Experience in a Remotely Delivered Laboratory Course Affect Student Learning?

ERIC Educational Resources Information Center

Abdel-Salam, Tarek; Kauffman, Paul J.; Crossman, Gary

2006-01-01

Educators question whether performing a laboratory experiment as an observer (non-hands-on), such as conducted in a distance education context, can be as effective a learning tool as personally performing the experiment in a laboratory environment. The present paper investigates this issue by comparing the performance of distance education…

Enrofloxacin degradation in broiler chicken manure under field conditions and its residuals effects to the environment.

PubMed

Slana, M; Žigon, D; Sollner-Dolenc, M

2017-05-01

The rate of degradation of enrofloxacin in broiler chicken manure has been characterised. Its degradation was investigated in manure excreted by broiler chickens in an intensively reared chicken facility; further, the degradation also followed after transfer of the excreta into the natural environment occurred. The effect of enrofloxacin and its degradation products on cucumber and tomato was also investigated. Enrofloxacin degradation was shown to take place within the rearing facility and also continuing after the manure was transferred into the environment. The rates of enrofloxacin degradation and the degree of degradation product formation in the manure heap incubated in the environment were condition specific, both variables depending on the manure sampling depth. The degradation half-lives ranged from 12.7 to 38.1 days for enrofloxacin and from 1.2 to 8.2 days for the main metabolite ciprofloxacin. Only the cucumber showed signs of toxicity when incubated with the composted manure immediately after transfer into field occurred (t = 0). No toxic effects to plants were observed when manure from the last incubation day (60th) of the field study and manure from the last incubation day of the laboratory degradation study were applied. The degradation study under field conditions showed that enrofloxacin and its degradation products degrade fast in the environment. Additionally, the toxic effects to plants decrease with the incubation time of manure containing enrofloxacin residuals.

Space Environment (Natural and Induced)

NASA Technical Reports Server (NTRS)

Kim, Myung-Hee Y.; George, Kerry A.; Cucinotta, Francis A.

2007-01-01

Considerable effort and improvement have been made in the study of ionizing radiation exposure occurring in various regions of space. Satellites and spacecrafts equipped with innovative instruments are continually refining particle data and providing more accurate information on the ionizing radiation environment. The major problem in accurate spectral definition of ionizing radiation appears to be the detailed energy spectra, especially at high energies, which is important parameter for accurate radiation risk assessment. Magnitude of risks posed by exposure to radiation in future space missions is subject to the accuracies of predictive forecast of event size of SPE, GCR environment, geomagnetic fields, and atmospheric radiation environment. Although heavy ion fragmentations and interactions are adequately resolved through laboratory study and model development, improvements in fragmentation cross sections for the light nuclei produced from HZE nuclei and their laboratory validation are still required to achieve the principal goal of planetary GCR simulation at a critical exposure site. More accurate prediction procedure for ionizing radiation environment can be made with a better understanding of the solar and space physics, fulfillment of required measurements for nuclear/atomic processes, and their validation and verification with spaceflights and heavy ion accelerators experiments. It is certainly true that the continued advancements in solar and space physics combining with physical measurements will strengthen the confidence of future manned exploration of solar system. Advancements in radiobiology will surely give the meaningful radiation hazard assessments for short and long term effects, by which appropriate and effective mitigation measures can be placed to ensure that humans safely live and work in the space, anywhere, anytime.

The Johns Hopkins Hunterian Laboratory Philosophy: Mentoring Students in a Scientific Neurosurgical Research Laboratory.

PubMed

Tyler, Betty M; Liu, Ann; Sankey, Eric W; Mangraviti, Antonella; Barone, Michael A; Brem, Henry

2016-06-01

After over 50 years of scientific contribution under the leadership of Harvey Cushing and later Walter Dandy, the Johns Hopkins Hunterian Laboratory entered a period of dormancy between the 1960s and early 1980s. In 1984, Henry Brem reinstituted the Hunterian Neurosurgical Laboratory, with a new focus on localized delivery of therapies for brain tumors, leading to several discoveries such as new antiangiogenic agents and Gliadel chemotherapy wafers for the treatment of malignant gliomas. Since that time, it has been the training ground for 310 trainees who have dedicated their time to scientific exploration in the lab, resulting in numerous discoveries in the area of neurosurgical research. The Hunterian Neurosurgical Laboratory has been a unique example of successful mentoring in a translational research environment. The laboratory's philosophy emphasizes mentorship, independence, self-directed learning, creativity, and people-centered collaboration, while maintaining productivity with a focus on improving clinical outcomes. This focus has been served by the diverse backgrounds of its trainees, both in regard to educational status as well as culturally. Through this philosophy and strong legacy of scientific contribution, the Hunterian Laboratory has maintained a positive and productive research environment that supports highly motivated students and trainees. In this article, the authors discuss the laboratory's training philosophy, linked to the principles of adult learning (andragogy), as well as the successes and the limitations of including a wide educational range of students in a neurosurgical translational laboratory and the phenomenon of combining clinical expertise with rigorous scientific training.

The Greenhouse Effect and Built Environment Education.

ERIC Educational Resources Information Center

Greenall Gough, Annette; Gough, Noel

The greenhouse effect has always existed. Without the greenhouse effect, Earth could well have the oven-like environment of Venus or the deep-freeze environment of Mars. There is some debate about how much the Earth's surface temperature will rise given a certain amount of increase in the amount of greenhouse gases such as carbon dioxide, nitrous…

Lawrence Berkeley Laboratory, Institutional Plan FY 1994--1999

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-09-01

The Institutional Plan provides an overview of the Lawrence Berkeley Laboratory mission, strategic plan, scientific initiatives, research programs, environment and safety program plans, educational and technology transfer efforts, human resources, and facilities needs. For FY 1994-1999 the Institutional Plan reflects significant revisions based on the Laboratory`s strategic planning process. The Strategic Plan section identifies long-range conditions that will influence the Laboratory, as well as potential research trends and management implications. The Initiatives section identifies potential new research programs that represent major long-term opportunities for the Laboratory, and the resources required for their implementation. The Scientific and Technical Programs section summarizesmore » current programs and potential changes in research program activity. The Environment, Safety, and Health section describes the management systems and programs underway at the Laboratory to protect the environment, the public, and the employees. The Technology Transfer and Education programs section describes current and planned programs to enhance the nation`s scientific literacy and human infrastructure and to improve economic competitiveness. The Human Resources section identifies LBL staff diversity and development program. The section on Site and Facilities discusses resources required to sustain and improve the physical plant and its equipment. The new section on Information Resources reflects the importance of computing and communication resources to the Laboratory. The Resource Projections are estimates of required budgetary authority for the Laboratory`s ongoing research programs. The Institutional Plan is a management report for integration with the Department of Energy`s strategic planning activities, developed through an annual planning process.« less

Housing environment influences stress-related hippocampal substrates and depression-like behavior.

PubMed

Ashokan, Archana; Hegde, Akshaya; Balasingham, Anushanthy; Mitra, Rupshi

2018-03-15

Rats are widely used animal models for biological psychiatry and neuroscience. Laboratory rats are typically housed in impoverished sensory environments. The lack of species-typical sensory environment might radically change the response of individual animals to stressful and/or threatening episodes. In this report, we demonstrate that behavioral and neural sequelae of chronic stress were modified by sensory environment of adult male rats. This includes effects of stress on the density of spines on CA3 hippocampal neurons, hippocampal neurogenesis and abundance of glucocorticoid or mineralocorticoid receptors. Enrichment also reduced depression-like behavior in a forced swim task. Stress and sensory enrichment evoked opposing effects on all the above endpoints. The sensory enrichment used in this report is of a relatively short duration provided during adulthood. This period excludes critical windows of greater plasticity during pre- and peripubertal stages. Our results suggest that standard housing practices for laboratory rats remain austere concerning sensory requirements of this species. Thus, even a moderate sensory enrichment is capable of reducing high stress-sensitivity and depressive-like behavior in standard laboratory rats. Copyright © 2018. Published by Elsevier B.V.

The Effect of Jigsaw Technique on the Students' Laboratory Material Recognition and Usage Skills in General Physics Laboratory-I Course

ERIC Educational Resources Information Center

Aydin, Abdullah; Biyikli, Filiz

2017-01-01

This research aims to compare the effects of Jigsaw technique from the cooperative learning methods and traditional learning method on laboratory material recognition and usage skills of students in General Physics Lab-I Course. This study was conducted with 63 students who took general physics laboratory-I course in the department of science…

The Automated Primate Research Laboratory (APRL)

NASA Technical Reports Server (NTRS)

Pace, N.; Smith, G. D.

1972-01-01

A description is given of a self-contained automated primate research laboratory to study the effects of weightlessness on subhuman primates. Physiological parameters such as hemodynamics, respiration, blood constituents, waste, and diet and nutrition are analyzed for abnormalities in the simulated space environment. The Southeast Asian pig-tailed monkey (Macaca nemistrina) was selected for the experiments owing to its relative intelligence and learning capacity. The objective of the program is to demonstrate the feasibility of a man-tended primate space flight experiment.

Computer listing of the effects of drugs on laboratory data

PubMed Central

Young, D. S.; Thomas, D. W.; Friedman, R. B.

1972-01-01

A listing of approximately 10000 effects of drugs on tests performed in clinical laboratories has been developed in a time-shared computer. The list contains a directory for matching proprietary and generic names of drugs and an explanation for the mode of action of the drug on each test. Each entry is supported by a bibliographical reference that contains the author's names, and the title of the article and journal. It is possible to search for specific `character strings' (word or words, number, etc) to obtain all the effects of a particular drug, or all drugs that affect a particular test, or even to search for a specific explanation for an effect. The system is undergoing trial in the Department's own computer to permit of automatic correlation of the effects of drugs with laboratory data from patients in one hospital ward. PMID:4648544

Cost Effectiveness of Adopted Quality Requirements in Hospital Laboratories

PubMed Central

HAMZA, Alneil; AHMED-ABAKUR, Eltayib; ABUGROUN, Elsir; BAKHIT, Siham; HOLI, Mohamed

2013-01-01

Background The present study was designed in quasi-experiment to assess adoption of the essential clauses of particular clinical laboratory quality management requirements based on international organization for standardization (ISO 15189) in hospital laboratories and to evaluate the cost effectiveness of compliance to ISO 15189. Methods: The quality management intervention based on ISO 15189 was conceded through three phases; pre – intervention phase, Intervention phase and Post-intervention phase. Results: In pre-intervention phase the compliance to ISO 15189 was 49% for study group vs. 47% for control group with P value 0.48, while the post intervention results displayed 54% vs. 79% for study group and control group respectively in compliance to ISO 15189 and statistically significant difference (P value 0.00) with effect size (Cohen’s d) of (0.00) in pre-intervention phase and (0.99) in post – intervention phase. The annual average cost per-test for the study group and control group was 1.80 ± 0.25 vs. 1.97 ± 0.39, respectively with P value 0.39 whereas the post-intervention results showed that the annual average total costs per-test for study group and control group was 1.57 ± 0.23 vs 2.08 ± 0.38, P value 0.019 respectively, with cost-effectiveness ratio of (0.88) in pre -intervention phase and (0.52) in post-intervention phase. Conclusion: The planned adoption of quality management requirements (QMS) in clinical laboratories had great effect to increase the compliance percent with quality management system requirement, raise the average total cost effectiveness, and improve the analytical process capability of the testing procedure. PMID:23967422

Cost effectiveness of adopted quality requirements in hospital laboratories.

PubMed

Hamza, Alneil; Ahmed-Abakur, Eltayib; Abugroun, Elsir; Bakhit, Siham; Holi, Mohamed

2013-01-01

The present study was designed in quasi-experiment to assess adoption of the essential clauses of particular clinical laboratory quality management requirements based on international organization for standardization (ISO 15189) in hospital laboratories and to evaluate the cost effectiveness of compliance to ISO 15189. The quality management intervention based on ISO 15189 was conceded through three phases; pre - intervention phase, Intervention phase and Post-intervention phase. In pre-intervention phase the compliance to ISO 15189 was 49% for study group vs. 47% for control group with P value 0.48, while the post intervention results displayed 54% vs. 79% for study group and control group respectively in compliance to ISO 15189 and statistically significant difference (P value 0.00) with effect size (Cohen's d) of (0.00) in pre-intervention phase and (0.99) in post - intervention phase. The annual average cost per-test for the study group and control group was 1.80 ± 0.25 vs. 1.97 ± 0.39, respectively with P value 0.39 whereas the post-intervention results showed that the annual average total costs per-test for study group and control group was 1.57 ± 0.23 vs 2.08 ± 0.38, P value 0.019 respectively, with cost-effectiveness ratio of (0.88) in pre -intervention phase and (0.52) in post-intervention phase. The planned adoption of quality management requirements (QMS) in clinical laboratories had great effect to increase the compliance percent with quality management system requirement, raise the average total cost effectiveness, and improve the analytical process capability of the testing procedure.

Orbitrap mass analyser for in situ characterisation of planetary environments: Performance evaluation of a laboratory prototype

NASA Astrophysics Data System (ADS)

Briois, Christelle; Thissen, Roland; Thirkell, Laurent; Aradj, Kenzi; Bouabdellah, Abdel; Boukrara, Amirouche; Carrasco, Nathalie; Chalumeau, Gilles; Chapelon, Olivier; Colin, Fabrice; Coll, Patrice; Cottin, Hervé; Engrand, Cécile; Grand, Noel; Lebreton, Jean-Pierre; Orthous-Daunay, François-Régis; Pennanech, Cyril; Szopa, Cyril; Vuitton, Véronique; Zapf, Pascal; Makarov, Alexander

2016-10-01

For decades of space exploration, mass spectrometry has proven to be a reliable instrumentation for the characterisation of the nature and energy of ionic and neutral, atomic and molecular species in the interplanetary medium and upper planetary atmospheres. It has been used as well to analyse the chemical composition of planetary and small bodies environments. The chemical complexity of these environments calls for the need to develop a new generation of mass spectrometers with significantly increased mass resolving power. The recently developed OrbitrapTM mass analyser at ultra-high resolution shows promising adaptability to space instrumentation, offering improved performances for in situ measurements. In this article, we report on our project named ;Cosmorbitrap; aiming at demonstrating the adaptability of the Orbitrap technology for in situ space exploration. We present the prototype that was developed in the laboratory for demonstration of both technical feasibility and analytical capabilities. A set of samples containing elements with masses ranging from 9 to 208 u has been used to evaluate the performance of the analyser, in terms of mass resolving power (reaching 474,000 at m/z 9) and ability to discriminate between isobaric interferences, accuracy of mass measurement (below 15 ppm) and determination of relative isotopic abundances (below 5%) of various samples. We observe a good agreement between the results obtained with the prototype and those of a commercial instrument. As the background pressure is a key parameter for in situ exploration of atmosphere planetary bodies, we study the effect of background gas on the performance of the Cosmorbitrap prototype, showing an upper limit for N2 in our set-up at 10-8 mbar. The results demonstrate the strong potential to adapt this technology to space exploration.

To Create Space on Earth: The Space Environment Simulation Laboratory and Project Apollo

NASA Technical Reports Server (NTRS)

Walters, Lori C.

2003-01-01

Few undertakings in the history of humanity can compare to the great technological achievement known as Project Apollo. Among those who witnessed Armstrong#s flickering television image were thousands of people who had directly contributed to this historic moment. Amongst those in this vast anonymous cadre were the personnel of the Space Environment Simulation Laboratory (SESL) at the Manned Spacecraft Center (MSC) in Houston, Texas. SESL houses two large thermal-vacuum chambers with solar simulation capabilities. At a time when NASA engineers had a limited understanding of the effects of extremes of space on hardware and crews, SESL was designed to literally create the conditions of space on Earth. With interior dimensions of 90 feet in height and a 55-foot diameter, Chamber A dwarfed the Apollo command/service module (CSM) it was constructed to test. The chamber#s vacuum pumping capacity of 1 x 10(exp -6) torr can simulate an altitude greater than 130 miles above the Earth. A "lunar plane" capable of rotating a 150,000-pound test vehicle 180 deg replicates the revolution of a craft in space. To reproduce the temperature extremes of space, interior chamber walls cool to -280F as two banks of carbon arc modules simulate the unfiltered solar light/heat of the Sun. With capabilities similar to that of Chamber A, early Chamber B tests included the Gemini modular maneuvering unit, Apollo EVA mobility unit and the lunar module. Since Gemini astronaut Charles Bassett first ventured into the chamber in 1966, Chamber B has assisted astronauts in testing hardware and preparing them for work in the harsh extremes of space.

Effect-Based Tools for Monitoring and Predicting the Ecotoxicological Effects of Chemicals in the Aquatic Environment

PubMed Central

Connon, Richard E.; Geist, Juergen; Werner, Inge

2012-01-01

Ecotoxicology faces the challenge of assessing and predicting the effects of an increasing number of chemical stressors on aquatic species and ecosystems. Herein we review currently applied tools in ecological risk assessment, combining information on exposure with expected biological effects or environmental water quality standards; currently applied effect-based tools are presented based on whether exposure occurs in a controlled laboratory environment or in the field. With increasing ecological relevance the reproducibility, specificity and thus suitability for standardisation of methods tends to diminish. We discuss the use of biomarkers in ecotoxicology including ecotoxicogenomics-based endpoints, which are becoming increasingly important for the detection of sublethal effects. Carefully selected sets of biomarkers allow an assessment of exposure to and effects of toxic chemicals, as well as the health status of organisms and, when combined with chemical analysis, identification of toxicant(s). The promising concept of “adverse outcome pathways (AOP)” links mechanistic responses on the cellular level with whole organism, population, community and potentially ecosystem effects and services. For most toxic mechanisms, however, practical application of AOPs will require more information and the identification of key links between responses, as well as key indicators, at different levels of biological organization, ecosystem functioning and ecosystem services. PMID:23112741

Can simple tank changes benefit the welfare of laboratory zebrafish Danio rerio?

PubMed

Lee, C J; Tyler, C R; Paull, G C

2018-03-01

This study examined the effects of simple changes in the tank environment on the wellbeing of laboratory-maintained zebrafish Danio rerio. Groups of D. rerio were either housed in stable environments (where they were maintained in the same tanks throughout the study) or in environments subject to change (where they were periodically moved to novel but identical tanks) and the effects of these treatments on morphometry, reproductive success and aggressive behaviour assessed. No effect of simple tank changes was found on body condition, reproductive output or aggression, for the periods of time studied, indicating that more complex scenarios in housing tank conditions are required for significant welfare benefits for captive D. rerio. © 2018 The Fisheries Society of the British Isles.

Managing laboratory automation

PubMed Central

Saboe, Thomas J.

1995-01-01

This paper discusses the process of managing automated systems through their life cycles within the quality-control (QC) laboratory environment. The focus is on the process of directing and managing the evolving automation of a laboratory; system examples are given. The author shows how both task and data systems have evolved, and how they interrelate. A BIG picture, or continuum view, is presented and some of the reasons for success or failure of the various examples cited are explored. Finally, some comments on future automation need are discussed. PMID:18925018

Managing laboratory automation.

PubMed

Saboe, T J

1995-01-01

This paper discusses the process of managing automated systems through their life cycles within the quality-control (QC) laboratory environment. The focus is on the process of directing and managing the evolving automation of a laboratory; system examples are given. The author shows how both task and data systems have evolved, and how they interrelate. A BIG picture, or continuum view, is presented and some of the reasons for success or failure of the various examples cited are explored. Finally, some comments on future automation need are discussed.

Laboratory Experiments on the Electrochemical Remediation of the Environment

ERIC Educational Resources Information Center

Ibanez, Jorge G.; Tellez-Giron, Monica; Alvarez, Diana

2004-01-01

Ferrate, which is a strong iron oxidant for removing pollutants from water, is developed electrochemically in the laboratory, and used for experiments simulating environmental situations. Thus, ferrate is a powerful oxidizing agent capable of destroying an immense variety of contaminants.

The Effectiveness of Blended Learning Environments

ERIC Educational Resources Information Center

Eryilmaz, Meltem

2015-01-01

The object of this experimental study is to measure the effectiveness of a blended learning environment which is laid out on the basis of features for face to face and online environments. The study was applied to 110 students who attend to Atilim University, Ankara, Turkey and take Introduction to Computers Course. During the application,…

Geochemical effects on the behavior of LLW radionuclides in soil/groundwater environments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krupka, K.M.; Sterne, R.J.

1995-12-31

Assessing the migration potential of radionuclides leached from low-level radioactive waste (LLW) and decommissioning sites necessitates information on the effects of sorption and precipitation on the concentrations of dissolved radionuclides. Such an assessment requires that the geochemical processes of aqueous speciation, complexation, oxidation/reduction, and ion exchange be taken into account. The Pacific Northwest National Laboratory (PNNL) is providing technical support to the U.S. Nuclear Regulatory Commission (NRC) for defining the solubility and sorption behavior of radionuclides in soil/ground-water environments associated with engineered cementitious LLW disposal systems and decommissioning sites. Geochemical modeling is being used to predict solubility limits for radionuclidesmore » under geochemical conditions associated with these environments. The solubility limits are being used as maximum concentration limits in performance assessment calculations describing the release of contaminants from waste sources. Available data were compiled regarding the sorption potential of radionuclides onto {open_quotes}fresh{close_quotes} cement/concrete where the expected pH of the cement pore waters will equal to or exceed 10. Based on information gleaned from the literature, a list of preferred minimum distribution coefficients (Kd`s) was developed for these radionuclides. The K{sub d} values are specific to the chemical environments associated with the evolution of the compositions of cement/concrete pore waters.« less

Effect of Accreditation on Accuracy of Diagnostic Tests in Medical Laboratories

PubMed Central

Jang, Mi-Ae; Yoon, Young Ahn; Song, Junghan; Kim, Jeong-Ho; Min, Won-Ki; Lee, Ji Sung

2017-01-01

Background Medical laboratories play a central role in health care. Many laboratories are taking a more focused and stringent approach to quality system management. In Korea, laboratory standardization efforts undertaken by the Korean Laboratory Accreditation Program (KLAP) and the Korean External Quality Assessment Scheme (KEQAS) may have facilitated an improvement in laboratory performance, but there are no fundamental studies demonstrating that laboratory standardization is effective. We analyzed the results of the KEQAS to identify significant differences between laboratories with or without KLAP and to determine the impact of laboratory standardization on the accuracy of diagnostic tests. Methods We analyzed KEQAS participant data on clinical chemistry tests such as albumin, ALT, AST, and glucose from 2010 to 2013. As a statistical parameter to assess performance bias between laboratories, we compared 4-yr variance index score (VIS) between the two groups with or without KLAP. Results Compared with the group without KLAP, the group with KLAP exhibited significantly lower geometric means of 4-yr VIS for all clinical chemistry tests (P<0.0001); this difference justified a high level of confidence in standardized services provided by accredited laboratories. Confidence intervals for the mean of each test in the two groups (accredited and non-accredited) did not overlap, suggesting that the means of the groups are significantly different. Conclusions These results confirmed that practice standardization is strongly associated with the accuracy of test results. Our study emphasizes the necessity of establishing a system for standardization of diagnostic testing. PMID:28224767

LABORATORY MISCONDUCT - WHAT CAN HAPPEN TO YOU?

EPA Science Inventory

Contracted laboratories perform a vast number of routine and special analytical services that are the foundation of decisions upon which rests the fate of the environment. Guiding these laboratories in the generation of environmental data has been the analytical protocols and ...

A laboratory medicine residency training program that includes clinical consultation and research.

PubMed

Spitzer, E D; Pierce, G F; McDonald, J M

1990-04-01

We describe a laboratory medicine residency training program that includes ongoing interaction with both clinical laboratories and clinical services as well as significant research experience. Laboratory medicine residents serve as on-call consultants in the interpretation of test results, design of testing strategies, and assurance of test quality. The consultative on-call beeper system was evaluated and is presented as an effective method of clinical pathology training that is well accepted by the clinical staff. The research component of the residency program is also described. Together, these components provide training in real-time clinical problem solving and prepare residents for the changing technological environment of the clinical laboratory. At the completion of the residency, the majority of the residents are qualified laboratory subspecialists and are also capable of running an independent research program.

Effect of Accreditation on Accuracy of Diagnostic Tests in Medical Laboratories.

PubMed

Jang, Mi Ae; Yoon, Young Ahn; Song, Junghan; Kim, Jeong Ho; Min, Won Ki; Lee, Ji Sung; Lee, Yong Wha; Lee, You Kyoung

2017-05-01

Medical laboratories play a central role in health care. Many laboratories are taking a more focused and stringent approach to quality system management. In Korea, laboratory standardization efforts undertaken by the Korean Laboratory Accreditation Program (KLAP) and the Korean External Quality Assessment Scheme (KEQAS) may have facilitated an improvement in laboratory performance, but there are no fundamental studies demonstrating that laboratory standardization is effective. We analyzed the results of the KEQAS to identify significant differences between laboratories with or without KLAP and to determine the impact of laboratory standardization on the accuracy of diagnostic tests. We analyzed KEQAS participant data on clinical chemistry tests such as albumin, ALT, AST, and glucose from 2010 to 2013. As a statistical parameter to assess performance bias between laboratories, we compared 4-yr variance index score (VIS) between the two groups with or without KLAP. Compared with the group without KLAP, the group with KLAP exhibited significantly lower geometric means of 4-yr VIS for all clinical chemistry tests (P<0.0001); this difference justified a high level of confidence in standardized services provided by accredited laboratories. Confidence intervals for the mean of each test in the two groups (accredited and non-accredited) did not overlap, suggesting that the means of the groups are significantly different. These results confirmed that practice standardization is strongly associated with the accuracy of test results. Our study emphasizes the necessity of establishing a system for standardization of diagnostic testing. © The Korean Society for Laboratory Medicine

Factors Influencing Laboratory Information System Effectiveness Through Strategic Planning in Shiraz Teaching Hospitals.

PubMed

Bahador, Fateme; Sharifian, Roxana; Farhadi, Payam; Jafari, Abdosaleh; Nematolahi, Mohtram; Shokrpour, Nasrin

This study aimed to develop and test a research model that examined 7effective factors on the effectiveness of laboratory information system (LIS) through strategic planning. This research was carried out on total laboratory staff, information technology staff, and laboratory managers in Shiraz (a city in the south of Iran) teaching hospitals by structural equation modeling approach in 2015. The results revealed that there was no significant positive relationship between decisions based on cost-benefit analysis and LIS functionality with LIS effectiveness, but there was a significant positive relationship between other factors and LIS effectiveness. As expected, high levels of strategic information system planning result in increasing LIS effectiveness. The results also showed that the relationship between cost-benefit analysis, LIS functionality, end-user involvement, and information technology-business alignment with strategic information system planning was significant and positive.

Regulatory issues in accreditation of toxicology laboratories.

PubMed

Bissell, Michael G

2012-09-01

Clinical toxicology laboratories and forensic toxicology laboratories operate in a highly regulated environment. This article outlines major US legal/regulatory issues and requirements relevant to accreditation of toxicology laboratories (state and local regulations are not covered in any depth). The most fundamental regulatory distinction involves the purposes for which the laboratory operates: clinical versus nonclinical. The applicable regulations and the requirements and options for operations depend most basically on this consideration, with clinical toxicology laboratories being directly subject to federal law including mandated options for accreditation and forensic toxicology laboratories being subject to degrees of voluntary or state government–required accreditation.

Incremental development and prototyping in current laboratory software development projects: Preliminary analysis

NASA Technical Reports Server (NTRS)

Griesel, Martha Ann

1988-01-01

Several Laboratory software development projects that followed nonstandard development processes, which were hybrids of incremental development and prototyping, are being studied. Factors in the project environment leading to the decision to use a nonstandard development process and affecting its success are analyzed. A simple characterization of project environment based on this analysis is proposed, together with software development approaches which have been found effective for each category. These approaches include both documentation and review requirements.

Effects of emergence time and early social rearing environment on behaviour of Atlantic salmon: consequences for juvenile fitness and smolt migration.

PubMed

Larsen, Martin H; Johnsson, Jörgen I; Winberg, Svante; Wilson, Alexander D M; Hammenstig, David; Thörnqvist, Per-Ove; Midwood, Jonathan D; Aarestrup, Kim; Höglund, Erik

2015-01-01

Consistent individual differences in behaviour have been well documented in a variety of animal taxa, but surprisingly little is known about the fitness and life-history consequences of such individual variation. In wild salmonids, the timing of fry emergence from gravel spawning nests has been suggested to be coupled with individual behavioural traits. Here, we further investigate the link between timing of spawning nest emergence and behaviour of Atlantic salmon (Salmo salar), test effects of social rearing environment on behavioural traits in fish with different emergence times, and assess whether behavioural traits measured in the laboratory predict growth, survival, and migration status in the wild. Atlantic salmon fry were sorted with respect to emergence time from artificial spawning nest into three groups: early, intermediate, and late. These emergence groups were hatchery-reared separately or in co-culture for four months to test effects of social rearing environment on behavioural traits. Twenty fish from each of the six treatment groups were then subjected to three individual-based behavioural tests: basal locomotor activity, boldness, and escape response. Following behavioural characterization, the fish were released into a near-natural experimental stream. Results showed differences in escape behaviour between emergence groups in a net restraining test, but the social rearing environment did not affect individual behavioural expression. Emergence time and social environment had no significant effects on survival, growth, and migration status in the stream, although migration propensity was 1.4 to 1.9 times higher for early emerging individuals that were reared separately. In addition, despite individuals showing considerable variation in behaviour across treatment groups, this was not translated into differences in growth, survival, and migration status. Hence, our study adds to the view that fitness (i.e., growth and survival) and life

The effect of the low Earth orbit environment on space solar cells: Results of the advanced photovoltaic experiment (S0014)

NASA Technical Reports Server (NTRS)

Brinker, David J.; Hickey, John R.

1992-01-01

The Advanced Photovoltaic Experiment (APEX), containing over 150 solar cells and sensors, was designed to generate laboratory reference standards as well as to explore the durability of a wide variety of space solar cells. Located on the leading edge of the Long Duration Exposure Facility (LDEF), APEX received the maximum possible dosage of atomic oxygen and ultraviolet radiation, as well as enormous numbers of impacts from micrometeoroids and debris. The effect of the low earth orbital (LEO) environment on the solar cells and materials of APEX will be discussed in this paper. The on-orbit performance of the solar cells, as well as a comparison of pre- and postflight laboratory performance measurements, will be presented.

Students' perceptions of constructivist Internet learning environments by a physics virtual laboratory: the gap between ideal and reality and gender differences.

PubMed

Chuang, Shih-Chyueh; Hwang, Fu-Kwun; Tsai, Chin-Chung

2008-04-01

The purpose of this study was to investigate the perceptions of Internet users of a physics virtual laboratory, Demolab, in Taiwan. Learners' perceptions of Internet-based learning environments were explored and the role of gender was examined by using preferred and actual forms of a revised Constructivist Internet-based Learning Environment Survey (CILES). The students expressed a clear gap between ideal and reality, and they showed higher preferences for many features of constructivist Internet-based learning environments than for features they had actually learned in Demolab. The results further suggested that male users prefer to be involved in the process of discussion and to show critical judgments. In addition, male users indicated they enjoyed the process of negotiation and discussion with others and were able to engage in reflective thoughts while learning in Demolab. In light of these findings, male users seemed to demonstrate better adaptability to the constructivist Internet-based learning approach than female users did. Although this study indicated certain differences between males and females in their responses to Internet-based learning environments, they also shared numerous similarities. A well-established constructivist Internet-based learning environment may encourage more female learners to participate in the science community.

SINGLE EVENT EFFECTS TEST FACILITY AT OAK RIDGE NATIONAL LABORATORY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Riemer, Bernie; Gallmeier, Franz X; Dominik, Laura J

2015-01-01

Increasing use of microelectronics of ever diminishing feature size in avionics systems has led to a growing Single Event Effects (SEE) susceptibility arising from the highly ionizing interactions of cosmic rays and solar particles. Single event effects caused by atmospheric radiation have been recognized in recent years as a design issue for avionics equipment and systems. To ensure a system meets all its safety and reliability requirements, SEE induced upsets and potential system failures need to be considered, including testing of the components and systems in a neutron beam. Testing of ICs and systems for use in radiation environments requiresmore » the utilization of highly advanced laboratory facilities that can run evaluations on microcircuits for the effects of radiation. This paper provides a background of the atmospheric radiation phenomenon and the resulting single event effects, including single event upset (SEU) and latch up conditions. A study investigating requirements for future single event effect irradiation test facilities and developing options at the Spallation Neutron Source (SNS) is summarized. The relatively new SNS with its 1.0 GeV proton beam, typical operation of 5000 h per year, expertise in spallation neutron sources, user program infrastructure, and decades of useful life ahead is well suited for hosting a world-class SEE test facility in North America. Emphasis was put on testing of large avionics systems while still providing tunable high flux irradiation conditions for component tests. Makers of ground-based systems would also be served well by these facilities. Three options are described; the most capable, flexible, and highest-test-capacity option is a new stand-alone target station using about one kW of proton beam power on a gas-cooled tungsten target, with dual test enclosures. Less expensive options are also described.« less

Sleep disturbance effects of traffic noise—A laboratory study on after effects

NASA Astrophysics Data System (ADS)

Öhrström, E.; Rylander, R.

1982-09-01

Body movements during sleep and subjective sleep quality, as well as mood and performance were investigated after exposure to intermittent and continuous traffic noise during the night. In a first experiment, six young subjects slept in the laboratory for five nights; in a second experiment 12 subjects slept six consecutive nights in the laboratory. A good dose-response relationship was obtained between intermittent noise and subjective sleep quality: i.e., the higher the noise level, the poorer the sleep quality. A similar dose-response relationship was found for body movements immediately following noise peaks during nights with intermittent noise. Performance and mood tended to be worse after intermittent noise. However, these effects did not increase with an increase in noise levels. Compared with intermittent noise, continuous noise had a significantly smaller effect on sleep quality. Mood and performance were not worse after continuous noise. The results suggest that increased attention should be paid to peak noise levels when standards for nocturnal noise are set.

Effects of the Family Environment: Gene-Environment Interaction and Passive Gene-Environment Correlation

ERIC Educational Resources Information Center

Price, Thomas S.; Jaffee, Sara R.

2008-01-01

The classical twin study provides a useful resource for testing hypotheses about how the family environment influences children's development, including how genes can influence sensitivity to environmental effects. However, existing statistical models do not account for the possibility that children can inherit exposure to family environments…

Calgary Laboratory Services

PubMed Central

2015-01-01

Calgary Laboratory Services provides global hospital and community laboratory services for Calgary and surrounding areas (population 1.4 million) and global academic support for the University of Calgary Cumming School of Medicine. It developed rapidly after the Alberta Provincial Government implemented an austerity program to address rising health care costs and to address Alberta’s debt and deficit in 1994. Over roughly the next year, all hospital and community laboratory test funding within the province was put into a single budget, fee codes for fee-for-service test billing were closed, roughly 40% of the provincial laboratory budget was cut, and roughly 40% of the pathologists left the province of Alberta. In Calgary, in the face of these abrupt changes in the laboratory environment, private laboratories, publicly funded hospital laboratories and the medical school department precipitously and reluctantly merged in 1996. The origin of Calgary Laboratory Services was likened to an “unhappy shotgun marriage” by all parties. Although such a structure could save money by eliminating duplicated services and excess capacity and could provide excellent city-wide clinical service by increasing standardization, it was less clear whether it could provide strong academic support for a medical school. Over the past decade, iterations of the Calgary Laboratory Services model have been implemented or are being considered in other Canadian jurisdictions. This case study analyzes the evolution of Calgary Laboratory Services, provides a metric-based review of academic performance over time, and demonstrates that this model, essentially arising as an unplanned experiment, has merit within a Canadian health care context. PMID:28725754

Shuttle/spacelab contamination environment and effects handbook

NASA Technical Reports Server (NTRS)

Bareiss, L. E.; Payton, R. M.; Papazian, H. A.

1986-01-01

This handbook is intended to assist users of the Spacelab/Space Transportation System by providing contamination environments and effects information that may be of value in planning, designing, manufacturing, and operating a space flight experiment. A summary of available molecular and particulate contamination data on the Space Transportation System and its facilities is presented. Contamination models, contamination effects, and protection methods information are also presented. In addition to contamination, the effects of the space environments at STS altitudes on spacecraft materials are included. Extensive references, bibliographies, and contacts are provided.

Regionalization of laboratory care: a viable option for the 21st century.

PubMed

Steiner, J W; Root, J M

1990-06-01

The conversion of the hospital laboratory to a cost center under pressure of prospective payment and fixed reimbursement is increasingly forcing hospitals to consider alternative modes for delivery of laboratory care. Changes in the health care environment, amended statutes and regulations, and, particularly, dramatic developments in laboratory equipment, methodologies, and data processing technology make it advisable and feasible to contemplate the creation of regional laboratory consortia. A fundamental step in this direction is the "commercialization" of the hospital laboratory through a change in focus from being an in-house support program to becoming a regional resource. By the same token, the hospital laboratory can become an effective competitor of independent laboratories and be reconverted to a profit center. Creation of hospital laboratory consortia in a splintered, competitive environment requires a committed entrepreneurial effort and convincing evidence of potential benefits. The sequence of steps needed to achieve regional laboratory integration include concerting the goals and objectives of the interested parties, creating an appropriate committee structure, conducting a feasibility assessment, identifying alternative organizational and operational options, selecting a favorite option viewed by all parties as a win/win proposition, developing a business plan, and determining an implementation action plan. The major disadvantages of regionalization of laboratories are employee displacement, potential leveling of quality standards, and reduced hospital control. The major advantages include elimination of duplicate capital, personnel, and service costs, improved efficiency through test batching, reduced unit costs, increased technical capability through staff, instrument, and systems sharing, disengagement from hospital-imposed limitations, strengthened ability to penetrate the marketplace, freeing of hospital space for more direct patient care

Systems engineering and integration: Advanced avionics laboratories

NASA Technical Reports Server (NTRS)

1990-01-01

In order to develop the new generation of avionics which will be necessary for upcoming programs such as the Lunar/Mars Initiative, Advanced Launch System, and the National Aerospace Plane, new Advanced Avionics Laboratories are required. To minimize costs and maximize benefits, these laboratories should be capable of supporting multiple avionics development efforts at a single location, and should be of a common design to support and encourage data sharing. Recent technological advances provide the capability of letting the designer or analyst perform simulations and testing in an environment similar to his engineering environment and these features should be incorporated into the new laboratories. Existing and emerging hardware and software standards must be incorporated wherever possible to provide additional cost savings and compatibility. Special care must be taken to design the laboratories such that real-time hardware-in-the-loop performance is not sacrificed in the pursuit of these goals. A special program-independent funding source should be identified for the development of Advanced Avionics Laboratories as resources supporting a wide range of upcoming NASA programs.

A Methodology to Obtain Learning Effective Laboratories with Learning Management System Integration

ERIC Educational Resources Information Center

Ruano, Ildefonso; Gamez, Javier; Dormido, Sebastian; Gomez, Juan

2016-01-01

Online laboratories are useful and valuable resources in high education, especially in engineering studies. This work presents a methodology to create effective laboratories for learning that interact with a Learning Management System (LMS) to achieve advanced integration. It is based on pedagogical aspects and considers not only the laboratory…

Learning Environment and Attitudes Associated with an Innovative Science Course Designed for Prospective Elementary Teachers

ERIC Educational Resources Information Center

Martin-Dunlop, Catherine; Fraser, Barry J.

2008-01-01

This study assessed the effectiveness of an innovative science course for improving prospective elementary teachers' perceptions of laboratory learning environments and attitudes towards science. The sample consisted of 27 classes with 525 female students in a large urban university. Changing students' ideas about science laboratory teaching and…

Lawrence Berkeley Laboratory Institutional Plan, FY 1993--1998

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chew, Joseph T.; Stroh, Suzanne C.; Maio, Linda R.

1992-10-01

The FY 1993--1998 Institutional Plan provides an overview of the Lawrence Berkeley Laboratory mission, strategic plan, scientific initiatives, research programs, environment and safety program plans, educational and technology transfer efforts, human resources, and facilities needs. The Strategic Plan section identifies long-range conditions that can influence the Laboratory, potential research trends, and several management implications. The Initiatives section identifies potential new research programs that represent major long-term opportunities for the Laboratory and the resources required for their implementation. The Scientific and Technical Programs section summarizes current programs and potential changes in research program activity. The Environment, Safety, and Health section describesmore » the management systems and programs underway at the Laboratory to protect the environment, the public, and the employees. The Technology Transfer and Education programs section describes current and planned programs to enhance the nation`s scientific literacy and human infrastructure and to improve economic competitiveness. The Human Resources section identifies LBL staff composition and development programs. The section on Site and Facilities discusses resources required to sustain and improve the physical plant and its equipment. The Resource Projections are estimates of required budgetary authority for the Laboratory`s ongoing research programs. The plan is an institutional management report for integration with the Department of Energy`s strategic planning activities that is developed through an annual planning process. The plan identifies technical and administrative directions in the context of the National Energy Strategy and the Department of Energy`s program planning initiatives. Preparation of the plan is coordinated by the Office for Planning and Development from information contributed by the Laboratory`s scientific and support divisions.« less

Recent Results of NASA's Space Environments and Effects Program

NASA Technical Reports Server (NTRS)

Minor, Jody L.; Brewer, Dana S.

1998-01-01

The Space Environments and Effects (SEE) Program is a multi-center multi-agency program managed by the NASA Marshall Space Flight Center. The program evolved from the Long Duration Exposure Facility (LDEF), analysis of LDEF data, and recognition of the importance of the environments and environmental effects on future space missions. It is a very comprehensive and focused approach to understanding the space environments, to define the best techniques for both flight and ground-based experimentation, to update the models which predict both the environments and the environmental effects on spacecraft, and finally to ensure that this information is properly maintained and inserted into spacecraft design programs. Formal funding of the SEE Program began initially in FY95. A NASA Research Announcement (NRA) solicited research proposals in the following categories: 1) Engineering environment definitions; 2) Environments and effects design guidelines; 3) Environments and effects assessment models and databases; and, 4) Flight/ground simulation/technology assessment data. This solicitation resulted in funding for eighteen technology development activities (TDA's). This paper will present and describe technical results rom the first set of TDA's of the SEE Program. It will also describe the second set of technology development activities which are expected to begin in January 1998. These new technology development activities will enable the SEE Program to start numerous new development activities in support of mission customer needs.

Complex Environments: Effects on Brain Development

ERIC Educational Resources Information Center

Wallace, Patricia

1974-01-01

Progress is now being made toward ascertaining the specific effects of rearing conditions on brain and behavior, the properties of the environment that contribute to these effects, and the developmental periods in which brain tissue is most sensitive to environmental modification. (Author/RH)

NATIONAL HEALTH AND ENVIRONMENTAL EFFECTS RESEARCH LABORATORY - ACCOMPLISHMENTS FOR FY 2001

EPA Science Inventory

This Annual Report showcases some of the scientific activities of the National Health and Environmental Effects Research Laboratory (NHEERL) in various health and environmental effects research areas. Where appropriate, the contributions of other collaborating research organizat...

D-VASim: an interactive virtual laboratory environment for the simulation and analysis of genetic circuits.

PubMed

Baig, Hasan; Madsen, Jan

2017-01-15

Simulation and behavioral analysis of genetic circuits is a standard approach of functional verification prior to their physical implementation. Many software tools have been developed to perform in silico analysis for this purpose, but none of them allow users to interact with the model during runtime. The runtime interaction gives the user a feeling of being in the lab performing a real world experiment. In this work, we present a user-friendly software tool named D-VASim (Dynamic Virtual Analyzer and Simulator), which provides a virtual laboratory environment to simulate and analyze the behavior of genetic logic circuit models represented in an SBML (Systems Biology Markup Language). Hence, SBML models developed in other software environments can be analyzed and simulated in D-VASim. D-VASim offers deterministic as well as stochastic simulation; and differs from other software tools by being able to extract and validate the Boolean logic from the SBML model. D-VASim is also capable of analyzing the threshold value and propagation delay of a genetic circuit model. D-VASim is available for Windows and Mac OS and can be downloaded from bda.compute.dtu.dk/downloads/. haba@dtu.dk, jama@dtu.dk. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

The ATLAS project: The effects of a constructionist digital laboratory project on undergraduate laboratory performance.

PubMed

Shoepe, Todd C; Cavedon, Dana K; Derian, Joseph M; Levy, Celine S; Morales, Amy

2015-01-01

Anatomical education is a dynamic field where developments in the implementation of constructive, situated-learning show promise in improving student achievement. The purpose of this study was to examine the effectiveness of an individualized, technology heavy project in promoting student performance in a combined anatomy and physiology laboratory course. Mixed-methods research was used to compare two cohorts of anatomy laboratories separated by the adoption of a new laboratory atlas project, which were defined as preceding (PRE) and following the adoption of the Anatomical Teaching and Learning Assessment Study (ATLAS; POST). The ATLAS project required the creation of a student-generated, photographic atlas via acquisition of specimen images taken with tablet technology and digital microscope cameras throughout the semester. Images were transferred to laptops, digitally labeled and photo edited weekly, and compiled into a digital book using Internet publishing freeware for final project submission. An analysis of covariance confirmed that student final examination scores were improved (P < 0.05) following the implementation of the laboratory atlas project (PRE, n = 75; POST, n = 90; means ± SE; 74.9 ± 0.9 versus 78.1 ± 0.8, respectively) after controlling for cumulative student grade point average. Analysis of questionnaires collected (n = 68) from the post group suggested students identified with atlas objectives, appreciated the comprehensive value in final examination preparation, and the constructionism involved, but recommended alterations in assignment logistics and the format of the final version. Constructionist, comprehensive term-projects utilizing student-preferred technologies could be used to improve performance toward student learning outcomes. © 2014 American Association of Anatomists.

Height effects in real and virtual environments.

PubMed

Simeonov, Peter I; Hsiao, Hongwei; Dotson, Brian W; Ammons, Douglas E

2005-01-01

The study compared human perceptions of height, danger, and anxiety, as well as skin conductance and heart rate responses and postural instability effects, in real and virtual height environments. The 24 participants (12 men, 12 women), whose average age was 23.6 years, performed "lean-over-the-railing" and standing tasks on real and comparable virtual balconies, using a surround-screen virtual reality (SSVR) system. The results indicate that the virtual display of elevation provided realistic perceptual experience and induced some physiological responses and postural instability effects comparable to those found in a real environment. It appears that a simulation of elevated work environment in a SSVR system, although with reduced visual fidelity, is a valid tool for safety research. Potential applications of this study include the design of virtual environments that will help in safe evaluation of human performance at elevation, identification of risk factors leading to fall incidents, and assessment of new fall prevention strategies.

A Coastal Environment Field and Laboratory Activity for an Undergraduate Geomorphology Course

ERIC Educational Resources Information Center

Ellis, Jean T.; Rindfleisch, Paul R.

2006-01-01

A field and laboratory exercise for an undergraduate geomorphology class is described that focuses on the beach. The project requires one day of fieldwork and two laboratory sessions. In the field, students measure water surface fluctuations (waves) with a pressure sensor, survey beach profiles, collect sediment samples, and observe the beach…

Space environment's effect on MODIS calibration

NASA Astrophysics Data System (ADS)

Dodd, J. L.; Wenny, B. N.; Chiang, K.; Xiong, X.

2010-09-01

The MODerate resolution Imaging Spectroradiometer flies on board the Earth Observing System (EOS) satellites Terra and Aqua in a sun-synchronous orbit that crosses the equator at 10:30 AM and 2:30 PM, respectively, at a low earth orbit (LEO) altitude of 705 km. Terra was launched on December 18,1999 and Aqua was launched on May 4, 2002. As the MODIS instruments on board these satellites continue to operate beyond the design lifetime of six years, the cumulative effect of the space environment on MODIS and its calibration is of increasing importance. There are several aspects of the space environment that impact both the top of atmosphere (TOA) calibration and, therefore, the final science products of MODIS. The south Atlantic anomaly (SAA), spacecraft drag, extreme radiative and thermal environment, and the presence of orbital debris have the potential to significantly impact both MODIS and the spacecraft, either directly or indirectly, possibly resulting in data loss. Efforts from the Terra and Aqua Flight Operations Teams (FOT), the MODIS Instrument Operations Team (IOT), and the MODIS Characterization Support Team (MCST) prevent or minimize external impact on the TOA calibrated data. This paper discusses specific effects of the space environment on MODIS and how they are minimized.

Exploring students' perceptions and performance on predict-observe-explain tasks in high school chemistry laboratory

NASA Astrophysics Data System (ADS)

Vadapally, Praveen

This study sought to understand the impact of gender and reasoning level on students' perceptions and performances of Predict-Observe-Explain (POE) laboratory tasks in a high school chemistry laboratory. Several literature reviews have reported that students at all levels have not developed the specific knowledge and skills that were expected from their laboratory work. Studies conducted over the last several decades have found that boys tend to be more successful than girls in science and mathematics courses. However, some recent studies have suggested that girls may be reducing this gender gap. This gender difference is the focal point of this research study, which was conducted at a mid-western, rural high school. The participants were 24 boys and 25 girls enrolled in two physical science classes taught by the same teacher. In this mixed methods study, qualitative and quantitative methods were implemented simultaneously over the entire period of the study. MANOVA statistics revealed significant effects due to gender and level of reasoning on the outcome variables, which were POE performances and perceptions of the chemistry laboratory environment. There were no significant interactions between these effects. For the qualitative method, IRB-approved information was collected, coded, grouped, and analyzed. This method was used to derive themes from students' responses on questionnaires and semi-structured interviews. Students with different levels of reasoning and gender were interviewed, and many of them expressed positive themes, which was a clear indication that they had enjoyed participating in the POE learning tasks and they had developed positive perceptions towards POE inquiry laboratory learning environment. When students are capable of formal reasoning, they can use an abstract scientific concept effectively and then relate it to the ideas they generate in their minds. Thus, instructors should factor the nature of students' thinking abilities into their

Ergonomics in an oral pathology laboratory: Back to basics in microscopy

PubMed Central

Sundaragiri, Krishna Sireesha; Shrivastava, Shikha; Sankhla, Bharat; Bhargava, Akshay

2014-01-01

Ergonomics is simply a science focused on “study of work” to reduce fatigue and discomfort through product design. A comprehensive ergonomics program for the pathology laboratory has become necessary to prevent the occurrence of work related musculoskeletal disorders (MSDs) and accidents. Most of the literature on ergonomics involve various web links or occasional studies on the effect of laboratory work and associated MSDs. A Google search was carried out corresponding to the terms “ergonomics”, “pathology laboratory”, “microscope”. All the relevant literature from web sources was sorted out and categorized. In this review, we intend to identify basic anthropometric factors, biomechanical risk factors, laboratory design considerations and specific microscopy-related considerations. The ultimate aim of ergonomics is to provide a safe environment for laboratory personnel to conduct their work and to allow maximum flexibility for safe research use. PMID:25364157

Engineered nanomaterials: toward effective safety management in research laboratories.

PubMed

Groso, Amela; Petri-Fink, Alke; Rothen-Rutishauser, Barbara; Hofmann, Heinrich; Meyer, Thierry

2016-03-15

It is still unknown which types of nanomaterials and associated doses represent an actual danger to humans and environment. Meanwhile, there is consensus on applying the precautionary principle to these novel materials until more information is available. To deal with the rapid evolution of research, including the fast turnover of collaborators, a user-friendly and easy-to-apply risk assessment tool offering adequate preventive and protective measures has to be provided. Based on new information concerning the hazards of engineered nanomaterials, we improved a previously developed risk assessment tool by following a simple scheme to gain in efficiency. In the first step, using a logical decision tree, one of the three hazard levels, from H1 to H3, is assigned to the nanomaterial. Using a combination of decision trees and matrices, the second step links the hazard with the emission and exposure potential to assign one of the three nanorisk levels (Nano 3 highest risk; Nano 1 lowest risk) to the activity. These operations are repeated at each process step, leading to the laboratory classification. The third step provides detailed preventive and protective measures for the determined level of nanorisk. We developed an adapted simple and intuitive method for nanomaterial risk management in research laboratories. It allows classifying the nanoactivities into three levels, additionally proposing concrete preventive and protective measures and associated actions. This method is a valuable tool for all the participants in nanomaterial safety. The users experience an essential learning opportunity and increase their safety awareness. Laboratory managers have a reliable tool to obtain an overview of the operations involving nanomaterials in their laboratories; this is essential, as they are responsible for the employee safety, but are sometimes unaware of the works performed. Bringing this risk to a three-band scale (like other types of risks such as biological, radiation

40 CFR 262.103 - What is the scope of the laboratory environmental management standard?

Code of Federal Regulations, 2014 CFR

2014-07-01

... University Laboratories XL Project-Laboratory Environmental Management Standard § 262.103 What is the scope... 40 Protection of Environment 26 2014-07-01 2014-07-01 false What is the scope of the laboratory environmental management standard? 262.103 Section 262.103 Protection of Environment ENVIRONMENTAL PROTECTION...

40 CFR 262.103 - What is the scope of the laboratory environmental management standard?

Code of Federal Regulations, 2012 CFR

2012-07-01

... University Laboratories XL Project-Laboratory Environmental Management Standard § 262.103 What is the scope... 40 Protection of Environment 27 2012-07-01 2012-07-01 false What is the scope of the laboratory environmental management standard? 262.103 Section 262.103 Protection of Environment ENVIRONMENTAL PROTECTION...

40 CFR 262.103 - What is the scope of the laboratory environmental management standard?

Code of Federal Regulations, 2013 CFR

2013-07-01

... University Laboratories XL Project-Laboratory Environmental Management Standard § 262.103 What is the scope... 40 Protection of Environment 27 2013-07-01 2013-07-01 false What is the scope of the laboratory environmental management standard? 262.103 Section 262.103 Protection of Environment ENVIRONMENTAL PROTECTION...

40 CFR 262.103 - What is the scope of the laboratory environmental management standard?

Code of Federal Regulations, 2011 CFR

2011-07-01

... University Laboratories XL Project-Laboratory Environmental Management Standard § 262.103 What is the scope... 40 Protection of Environment 26 2011-07-01 2011-07-01 false What is the scope of the laboratory environmental management standard? 262.103 Section 262.103 Protection of Environment ENVIRONMENTAL PROTECTION...

Space Radiation Effects Laboratory

NASA Technical Reports Server (NTRS)

1969-01-01

The SREL User's Handbook is designed to provide information needed by those who plan experiments involving the accelerators at this laboratory. Thus the Handbook will contain information on the properties of the machines, the beam parameters, the facilities and services provided for experimenters, etc. This information will be brought up to date as new equipment is added and modifications accomplished. This Handbook is influenced by the many excellent models prepared at other accelerator laboratories. In particular, the CERN Synchrocyclotron User's Handbook (November 1967) is closely followed in some sections, since the SREL Synchrocyclotron is a duplicate of the CERN machine. We wish to thank Dr. E. G. Michaelis for permission to draw so heavily on his work, particularly in Section II of this Handbook. We hope that the Handbook will prove useful, and will welcome suggestions and criticism.

"I got it on Ebay!": cost-effective approach to surgical skills laboratories.

PubMed

Schneider, Ethan; Schenarts, Paul J; Shostrom, Valerie; Schenarts, Kimberly D; Evans, Charity H

2017-01-01

Surgical education is witnessing a surge in the use of simulation. However, implementation of simulation is often cost-prohibitive. Online shopping offers a low budget alternative. The aim of this study was to implement cost-effective skills laboratories and analyze online versus manufacturers' prices to evaluate for savings. Four skills laboratories were designed for the surgery clerkship from July 2014 to June 2015. Skills laboratories were implemented using hand-built simulation and instruments purchased online. Trademarked simulation was priced online and instruments priced from a manufacturer. Costs were compiled, and a descriptive cost analysis of online and manufacturers' prices was performed. Learners rated their level of satisfaction for all educational activities, and levels of satisfaction were compared. A total of 119 third-year medical students participated. Supply lists and costs were compiled for each laboratory. A descriptive cost analysis of online and manufacturers' prices showed online prices were substantially lower than manufacturers, with a per laboratory savings of: $1779.26 (suturing), $1752.52 (chest tube), $2448.52 (anastomosis), and $1891.64 (laparoscopic), resulting in a year 1 savings of $47,285. Mean student satisfaction scores for the skills laboratories were 4.32, with statistical significance compared to live lectures at 2.96 (P < 0.05) and small group activities at 3.67 (P < 0.05). A cost-effective approach for implementation of skills laboratories showed substantial savings. By using hand-built simulation boxes and online resources to purchase surgical equipment, surgical educators overcome financial obstacles limiting the use of simulation and provide learning opportunities that medical students perceive as beneficial. Copyright © 2016 Elsevier Inc. All rights reserved.

A multivariate assessment of the effect of the laboratory homework component of a microcomputer-based laboratory for a college freshman physics course

NASA Astrophysics Data System (ADS)

Ramlo, Susan E.

Microcomputer-based laboratories (MBLs) have been defined as software that uses an electronic probe to collect information about a physical system and then converts that information into graphical systems in real-time. Realtime Physics Laboratories (RTP) are an example of laboratories that combine the use of MBLs with collaboration and guided-inquiry. RTP Mechanics Laboratories include both laboratory activities and laboratory homework for the first semester of college freshman physics courses. Prior research has investigated the effectiveness of the RTP laboratories as a package (laboratory activities with laboratory homework). In this study, an experimental-treatment had students complete both the RTP laboratory activity and the associated laboratory homework during the same laboratory period. Observations of this treatment indicated that students primarily consulted the laboratory instructor and referred to their completed laboratory activity while completing the homework in their collaborative groups. In the control-treatment, students completed the laboratory homework outside the laboratory period. Measures of force and motion conceptual understanding included the Force and Motion Conceptual Understanding (FMCE), a 47 multiple-choice question test. Analyses of the FMCE indicated that it is both a reliable and a valid measure of force and motion conceptual understanding. A distinct, five-factor structure for the FMCE post-test answers reflected specific concepts related to force and motion. However, the three FMCE pretest factors were less distinct. Analysis of the experimental-treatment, compared to a control-treatment, included multiple regression analysis with covariates of age, prior physics-classroom experience, and the three FMCE pretest factors. Criterion variables included each of the five post-test factors, the total laboratory homework score, and a group of seven exam questions. The results were all positive, in favor of the experimental

The long-term effects of the micrometeoroid and orbital debris environments on materials used in space

NASA Technical Reports Server (NTRS)

Cour-Palais, Burton G.

1989-01-01

The long-term effects of the orbital debris and micrometeoroid environments on materials that are current candidates for use on space vehicles are discussed. In addition, the limits of laboratory testing to determine these effects are defined and the need for space-based data is delineated. The impact effects discussed are divided into primary and secondary surfaces. Primary surfaces are those that are subject to erosion, pitting, the degradation and delamination of optical coatings, perforation of atomic oxygen erosion barriers, vapor coating of optics and the production of secondary ejecta particles. Secondary surfaces are those that are affected by the result of the perforation of primary surfaces, for example, vapor deposition on electronic components and other sensitive equipment, and the production of fragments with damage potential to internal pressurized elements. The material properties and applications that are required to prevent or lessen the effects described, are defined.

Underground laboratories in Asia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lin, Shin Ted, E-mail: linst@mails.phys.sinica.edu.tw; Yue, Qian, E-mail: yueq@mail.tsinghua.edu.cn

2015-08-17

Deep underground laboratories in Asia have been making huge progress recently because underground sites provide unique opportunities to explore the rare-event phenomena for the study of dark matter searches, neutrino physics and nuclear astrophysics as well as the multi-disciplinary researches based on the low radioactive environments. The status and perspectives of Kamioda underground observatories in Japan, the existing Y2L and the planned CUP in Korea, India-based Neutrino Observatory (INO) in India and China JinPing Underground Laboratory (CJPL) in China will be surveyed.

Underground laboratories in Asia

NASA Astrophysics Data System (ADS)

Lin, Shin Ted; Yue, Qian

2015-08-01

Deep underground laboratories in Asia have been making huge progress recently because underground sites provide unique opportunities to explore the rare-event phenomena for the study of dark matter searches, neutrino physics and nuclear astrophysics as well as the multi-disciplinary researches based on the low radioactive environments. The status and perspectives of Kamioda underground observatories in Japan, the existing Y2L and the planned CUP in Korea, India-based Neutrino Observatory (INO) in India and China JinPing Underground Laboratory (CJPL) in China will be surveyed.

Implementing a resource management program for accreditation process at the medical laboratory.

PubMed

Yenice, Sedef

2009-03-01

To plan for and provide adequate resources to meet the mission and goals of a medical laboratory in compliance with the requirements for laboratory accreditation by Joint Commission International. The related policies and procedures were developed based on standard requirements for resource management. Competency assessment provided continuing education and performance feedback to laboratory employees. Laboratory areas were designed for the efficient and safe performance of laboratory work. A physical environment was built up where hazards were controlled and personnel activities were managed to reduce the risk of injuries. An Employees Occupational Safety and Health Program (EOSHP) was developed to address all types of hazardous materials and wastes. Guidelines were defined to verify that the methods would produce accurate and reliable results. An active resource management program will be an effective way of assuring that systems are in control and continuous improvement is in progress.

News | Argonne National Laboratory

Science.gov Websites

Skip to main content Argonne National Laboratory Toggle Navigation Toggle Search Home Learning solvers Home Learning Center Undergraduates Graduates Faculty Partners News & Events News & Events -4114 Contact Us Argonne Educational Programs is committed to providing a learning environment that

Virtual Environments in Scientific Visualization

NASA Technical Reports Server (NTRS)

Bryson, Steve; Lisinski, T. A. (Technical Monitor)

1994-01-01

Virtual environment technology is a new way of approaching the interface between computers and humans. Emphasizing display and user control that conforms to the user's natural ways of perceiving and thinking about space, virtual environment technologies enhance the ability to perceive and interact with computer generated graphic information. This enhancement potentially has a major effect on the field of scientific visualization. Current examples of this technology include the Virtual Windtunnel being developed at NASA Ames Research Center. Other major institutions such as the National Center for Supercomputing Applications and SRI International are also exploring this technology. This talk will be describe several implementations of virtual environments for use in scientific visualization. Examples include the visualization of unsteady fluid flows (the virtual windtunnel), the visualization of geodesics in curved spacetime, surface manipulation, and examples developed at various laboratories.

Efficacy of a Virtual Teaching Assistant in an Open Laboratory Environment for Electric Circuits

ERIC Educational Resources Information Center

Saleheen, Firdous; Wang, Zicong; Picone, Joseph; Butz, Brian P.; Won, Chang-Hee

2018-01-01

In order to provide an on-demand, open electrical engineering laboratory, we developed an innovative software-based Virtual Open Laboratory Teaching Assistant (VOLTA). This web-based virtual assistant provides laboratory instructions, equipment usage videos, circuit simulation assistance, and hardware implementation diagnostics. VOLTA allows…

Computing, Environment and Life Sciences | Argonne National Laboratory

Science.gov Websites

engineer receives prestigious medal August 18, 2016 Software optimized on Mira advances design of mini » Back to top Twitter Flickr Facebook Linked In YouTube Pinterest Google Plus Computing, Environment and

The effects of laboratory housing and spatial enrichment on brain size and metabolic rate in the eastern mosquitofish, Gambusia holbrooki

PubMed Central

Turschwell, Mischa P.; White, Craig R.

2016-01-01

ABSTRACT It has long been hypothesised that there is a functional correlation between brain size and metabolic rate in vertebrates. The present study tested this hypothesis in wild-caught adult mosquitofish Gambusia holbrooki by testing for an intra-specific association between resting metabolic rate (RMR) and brain size while controlling for variation in body size, and through the examination of the effects of spatial enrichment and laboratory housing on body mass-independent measures of brain size and RMR. Controlling for body mass, there was no relationship between brain size and RMR in wild-caught fish. Contrary to predictions, spatial enrichment caused a decrease in mass-independent brain size, highlighting phenotypic plasticity in the adult brain. As expected, after controlling for differences in body size, wild-caught fish had relatively larger brains than fish that had been maintained in the laboratory for a minimum of six weeks, but wild-caught fish also had significantly lower mass-independent RMR. This study demonstrates that an organisms' housing environment can cause significant plastic changes to fitness related traits including brain size and RMR. We therefore conclude that current standard laboratory housing conditions may cause captive animals to be non-representative of their wild counterparts, potentially undermining the transferability of previous laboratory-based studies of aquatic ectothermic vertebrates to wild populations. PMID:26794608

The balanced scorecard: sustainable performance assessment for forensic laboratories.

PubMed

Houck, Max; Speaker, Paul J; Fleming, Arron Scott; Riley, Richard A

2012-12-01

The purpose of this article is to introduce the concept of the balanced scorecard into the laboratory management environment. The balanced scorecard is a performance measurement matrix designed to capture financial and non-financial metrics that provide insight into the critical success factors for an organization, effectively aligning organization strategy to key performance objectives. The scorecard helps organizational leaders by providing balance from two perspectives. First, it ensures an appropriate mix of performance metrics from across the organization to achieve operational excellence; thereby the balanced scorecard ensures that no single or limited group of metrics dominates the assessment process, possibly leading to long-term inferior performance. Second, the balanced scorecard helps leaders offset short term performance pressures by giving recognition and weight to long-term laboratory needs that, if not properly addressed, might jeopardize future laboratory performance. Copyright © 2012 Forensic Science Society. Published by Elsevier Ireland Ltd. All rights reserved.

The photoelectric effect and study of the diffraction of light: Two new experiments in UNILabs virtual and remote laboratories network

NASA Astrophysics Data System (ADS)

Pedro Sánchez, Juan; Sáenz, Jacobo; de la Torre, Luis; Carreras, Carmen; Yuste, Manuel; Heradio, Rubén; Dormido, Sebastián

2016-05-01

This work describes two experiments: "study of the diffraction of light: Fraunhofer approximation" and "the photoelectric effect". Both of them count with a virtual, simulated, version of the experiment as well as with a real one which can be operated remotely. The two previous virtual and remote labs (built using Easy Java(script) Simulations) are integrated in UNILabs, a network of online interactive laboratories based on the free Learning Management System Moodle. In this web environment, students can find not only the virtual and remote labs but also manuals with related theory, the user interface description for each application, and so on.

Wage, Work Environment, and Staffing: Effects on Nurse Outcomes

PubMed Central

McHugh, Matthew D.; Ma, Chenjuan

2015-01-01

Research has shown that hospitals with better nurse staffing and work environments have better nurse outcomes—less burnout, job dissatisfaction, and intention to leave the job. Many studies, however, have not accounted for wage effects, which may confound findings. By using a secondary analysis with cross-sectional administrative data and a four-state survey of nurses, we investigated how wage, work environment, and staffing were associated with nurse outcomes. Logistic regression models, with and without wage, were used to estimate the effects of work environment and staffing on burnout, job dissatisfaction, and intent to leave. We discovered that wage was associated with job dissatisfaction and intent to leave but had little influence on burnout, while work environment and average patient-to-nurse ratio still have considerable effects on nurse outcomes. Wage is important for good nurse outcomes, but it does not diminish the significant influence of work environment and staffing on nurse outcomes. PMID:25121923

Wage, work environment, and staffing: effects on nurse outcomes.

PubMed

McHugh, Matthew D; Ma, Chenjuan

2014-01-01

Research has shown that hospitals with better nurse staffing and work environments have better nurse outcomes-less burnout, job dissatisfaction, and intention to leave the job. Many studies, however, have not accounted for wage effects, which may confound findings. By using a secondary analysis with cross-sectional administrative data and a four-state survey of nurses, we investigated how wage, work environment, and staffing were associated with nurse outcomes. Logistic regression models, with and without wage, were used to estimate the effects of work environment and staffing on burnout, job dissatisfaction, and intent to leave. We discovered that wage was associated with job dissatisfaction and intent to leave but had little influence on burnout, while work environment and average patient-to-nurse ratio still have considerable effects on nurse outcomes. Wage is important for good nurse outcomes, but it does not diminish the significant influence of work environment and staffing on nurse outcomes. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

Augmented Reflective Learning and Knowledge Retention Perceived among Students in Classrooms Involving Virtual Laboratories

ERIC Educational Resources Information Center

Achuthan, Krishnashree; Francis, Saneesh P.; Diwakar, Shyam

2017-01-01

Learning theories converge on the principles of reflective learning processes and perceive them as fundamental to effective learning. Traditional laboratory education in science and engineering often happens in highly resource-constrained environments that compromise some of the learning objectives. This paper focuses on characterizing three…

Mobile wireless network for the urban environment

NASA Astrophysics Data System (ADS)

Budulas, Peter; Luu, Brian; Gopaul, Richard

2005-05-01

As the Army transforms into the Future Force, particular attention must be paid to operations in Complex and Urban Terrain. Our adversaries increasingly draw us into operations in the urban environment and one can presume that this trend will continue in future battles. In order to ensure that the United States Army maintains battlefield dominance, the Army Research Laboratory (ARL) is developing technology to equip our soldiers for the urban operations of the future. Sophisticated soldier borne systems will extend sensing to the individual soldier, and correspondingly, allow the soldier to establish an accurate picture of their surrounding environment utilizing information from local and remote assets. Robotic platforms will be an integral part of the future combat team. These platforms will augment the team with remote sensing modalities, task execution capabilities, and enhanced communication systems. To effectively utilize the products provided by each of these systems, collected data must be exchanged in real time to all affected entities. Therefore, the Army Research Laboratory is also developing the technology that will be required to support high bandwidth mobile communication in urban environments. This technology incorporates robotic systems that will allow connectivity in areas unreachable by traditional systems. This paper will address some of the issues of providing wireless connectivity in complex and urban terrain. It will further discuss approaches developed by the Army Research Laboratory to integrate communications capabilities into soldier and robotic systems and provide seamless connectivity between the elements of a combat team, and higher echelons.

Relation Between the Overall Impression of the Sound Environment and Types and Loudness of Environmental Sounds

NASA Astrophysics Data System (ADS)

KAWAI, K.; YANO, T.

2002-02-01

This paper reports an experimental study determining the effects of the type and loudness of individual sounds on the overall impression of the sound environment. Field and laboratory experiments were carried out. In each experiment, subjects evaluated the sound environment presented, which consisted of combinations of three individual sounds of road traffic, singing crickets and the murmuring of a river, with five bipolar adjective scales such as Good-Bad, Active-Calm and Natural-Artificial. Overall loudness had the strongest effect on most types of evaluations; relative SPL has a greater effect than overall loudness on a particular evaluation of the natural-artificial scale. The test sounds in the field experiment were generally evaluated as more good and more natural than those in the laboratory. The results of comparisons between laboratory and field sounds indicate a difference in the trend between them. This difference may be explained by the term of selective listening but that needs further investigation.

Exploration Laboratory Analysis

NASA Technical Reports Server (NTRS)

Krihak, M.; Ronzano, K.; Shaw, T.

2016-01-01

The Exploration Laboratory Analysis (ELA) project supports the Exploration Medical Capability (ExMC) risk to minimize or reduce the risk of adverse health outcomes and decrements in performance due to in-flight medical capabilities on human exploration missions. To mitigate this risk, the availability of inflight laboratory analysis instrumentation has been identified as an essential capability for manned exploration missions. Since a single, compact space-ready laboratory analysis capability to perform all exploration clinical measurements is not commercially available, the ELA project objective is to demonstrate the feasibility of emerging operational and analytical capability as a biomedical diagnostics precursor to long duration manned exploration missions. The initial step towards ground and flight demonstrations in fiscal year (FY) 2015 was the down selection of platform technologies for demonstrations in the space environment. The technologies selected included two Small Business Innovation Research (SBIR) performers: DNA Medicine Institutes rHEALTH X and Intelligent Optical Systems later flow assays combined with Holomics smartphone analyzer. The selection of these technologies were based on their compact size, breadth of analytical capability and favorable ability to process fluids in a space environment, among several factors. These two technologies will be advanced to meet ground and flight demonstration success criteria and requirements that will be finalized in FY16. Also, the down selected performers will continue the technology development phase towards meeting prototype deliverables in either late 2016 or 2017.

Exploration Laboratory Analysis

NASA Technical Reports Server (NTRS)

Krihak, M.; Ronzano, K.; Shaw, T.

2016-01-01

The Exploration Laboratory Analysis (ELA) project supports the Exploration Medical Capability (ExMC) risk to minimize or reduce the risk of adverse health outcomes and decrements in performance due to in-flight medical capabilities on human exploration missions. To mitigate this risk, the availability of inflight laboratory analysis instrumentation has been identified as an essential capability for manned exploration missions. Since a single, compact space-ready laboratory analysis capability to perform all exploration clinical measurements is not commercially available, the ELA project objective is to demonstrate the feasibility of emerging operational and analytical capability as a biomedical diagnostics precursor to long duration manned exploration missions. The initial step towards ground and flight demonstrations in fiscal year (FY) 2015 was the downselection of platform technologies for demonstrations in the space environment. The technologies selected included two Small Business Innovation Research (SBIR) performers: DNA Medicine Institute's rHEALTH X and Intelligent Optical System's lateral flow assays combined with Holomic's smartphone analyzer. The selection of these technologies were based on their compact size, breadth of analytical capability and favorable ability to process fluids in a space environment, among several factors. These two technologies will be advanced to meet ground and flight demonstration success criteria and requirements. The technology demonstrations and metrics for success will be finalized in FY16. Also, the downselected performers will continue the technology development phase towards meeting prototype deliverables in either late 2016 or 2017.

Clinical laboratory studies of disinfection with Sporicidin.

PubMed Central

Isenberg, H D

1985-01-01

The clinical microbiology laboratory evaluation of disinfectants can serve as a guide for their application to reduce hospital-acquired infections. The use of Sporicidin, a glutaraldehyde-phenol formulation, was evaluated by the application of modified MIC and MBC determinations for standard organisms. In addition, the effect of this formulation on bacteria that may proliferate in water at ambient temperatures was studied. This investigation indicated that such studies can help the clinical microbiologist to guide the use of disinfectants and sterilants for the maintenance of a safe hospital environment. PMID:3932457

Extending the Marine Microcosm Laboratory

ERIC Educational Resources Information Center

Ryswyk, Hal Van; Hall, Eric W.; Petesch, Steven J.; Wiedeman, Alice E.

2007-01-01

The traditional range of marine microcosm laboratory experiments is presented as an ideal environment to teach the entire analysis process. The microcosm lab provides student-centered approach with opportunities for collaborative learning and to develop critical communication skills.

Effective Laboratory Experiences for Students with Disabilities: The Role of a Student Laboratory Assistant

NASA Astrophysics Data System (ADS)

Pence, Laura E.; Workman, Harry J.; Riecke, Pauline

2003-03-01

Two separate experiences with students whose disabilities significantly limited the number of laboratory activities they could accomplish independently has given us a general experience base for determining successful strategies for accommodating students facing these situatiuons. For a student who had substantially limited physical mobility and for a student who had no visual ability, employing a student laboratory assistant allowed the students with disabilities to have a productive and positive laboratory experience. One of the priorities in these situations should be to avoid depersonalizing the student with a disability. Interactions with the instructor and with other students should focus on the disabled student rather than the student laboratory assistant who may be carrying out specific tasks. One of the most crucial aspects of a successful project is the selection of a laboratory assistant who has excellent interpersonal skills and who will add his or her creativity to that of the student with a disability to meet unforeseen challenges. Other considerations are discussed, such as the importance of advance notification that a disabled student has enrolled in a course as well as factors that should contribute to choosing an optimum laboratory station for each situation.

Laboratory administration--capital budgeting.

PubMed

Butros, F

1997-01-01

The process of capital budgeting varies among different health-care institutions. Understanding the concept of present value of money, incremental cash flow statements, and the basic budgeting techniques will enable the laboratory manager to make the rational and logical decisions that are needed in today's competitive health-care environment.

Laboratory investigations

NASA Technical Reports Server (NTRS)

Russell, Ray W.

1988-01-01

Laboratory studies related to cometary grains and the nuclei of comets can be broken down into three areas which relate to understanding the spectral properties, the formation mechanisms, and the evolution of grains and nuclei: (1) Spectral studies to be used in the interpretation of cometary spectra; (2) Sample preparation experiments which may shed light on the physical nature and history of cometary grains and nuclei by exploring the effects on grain emissivities resulting from the ways in which the samples are created; and (3) Grain processing experiments which should provide insight on the interaction of cometary grains with the environment in the immediate vicinity of the cometary nucleus as the comet travels from the Oort cloud through perihelion, and perhaps even suggestions regarding the relationship between interstellar grains and cometary matter. A summary is presented with a different view of lab experiments than is found in the literature, concentrating on measurement techniques and sample preparations especially relevant to cometary dust.

A winning formula for new laboratories.

PubMed

Robinson, Tim

2012-11-01

High quality architecture and extensive stakeholder consultations have transformed the delivery of Laboratory Medicine within Sheffield Teaching Hospitals NHS Foundation Trust (NHSFT), explains Tim Robinson, senior architect at Race Cottam Associates, the architects on a scheme that has seen laboratory services from across the city consolidated within one modern, spacious, well-lit, and well-equipped building that should provide an extremely positive, 'future-proofed' working environment for staff.

Growth of juvenile hard clams in Narragansett Bay after laboratory exposure to low pH

EPA Science Inventory

Ocean uptake of carbon dioxide is causing decreases in pH and the concentration of carbonate ions used by marine organisms during shell and skeletal formation. When these conditions are reproduced in laboratory environments and field enclosures, effects on biological rates such ...

Space Environment and Effects System (SEES)

NASA Astrophysics Data System (ADS)

Higashio, Nana; Obara, Takahiro; Matsumoto, Haruhisa; Koga, Kiyokazu; Koshiishi, Hideki

Space environment group in JAXA has installed insturments to measure space environment on eleven satellites. In the last year, the biggest instrument called SEDA-AP (Space Environment Data Acquision equipment -Attached Paylod) was atteched to the palette of JEM (ISS). On the other hand, we have a web site, "Space Environment and Effects System(SEES)". This system consisits of four parts. First part is to provide data that were obtained from these insturments. There are 18 kinds of mesurments, for example, radiation, magnetic field and so on. In 1994, Anik E-1 and Anik E-2 were broken by solar storm and we could catch the abnormal data from our instrument. Second part is a warning system. Many Japanese satellites are working around the earth and they are always exposed to radioactivity in space. So we predict the the radiation data in two days and if the expected value is over the threshold of safety, we inform a warning massage to users who want to keep their satellites safe. And we also provide the warning massage for Japanese astronauts who stay at ISS. Third part is the tool of the space environment /satellite environment models. There are 12 kinds of environment models which are constructed from 90 space environment models, for example, radiation model, solar activity model and so on. If you register your infomation in the SEES web site, you can simulate space environment by using them. Fourth part is providing the 2D and 3D infomations of satellite's orvits. This show the satelllite's position on the world map at a paticular time. If you want to use this system, please visit our SEES page at (http://seesproxy.tksc.jaxa.jp/fw/dfw/SEES/index.html ).

Effect of Using Separate Laboratory and Lecture Courses for Introductory Crop Science on Student Performance.

ERIC Educational Resources Information Center

Wiebold, W. J.; Slaughter, Leon

1986-01-01

Reviews a study that examined the effects of laboratories on the grade performance of undergraduates in an introductory crop science course. Results indicated that students enrolled in lecture and laboratory concurrently did not receive higher lecture grades than students enrolled solely in lecture, but did have higher laboratory grades. (ML)

Effect of Virtual Analytical Chemistry Laboratory on Enhancing Student Research Skills and Practices

ERIC Educational Resources Information Center

Bortnik, Boris; Stozhko, Natalia; Pervukhina, Irina; Tchernysheva, Albina; Belysheva, Galina

2017-01-01

This article aims to determine the effect of a virtual chemistry laboratory on university student achievement. The article describes a model of a laboratory course that includes a virtual component. This virtual component is viewed as a tool of student pre-lab autonomous learning. It presents electronic resources designed for a virtual laboratory…

Lawrence Berkeley Laboratory Institutional Plan, FY 1993--1998

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-10-01

The FY 1993--1998 Institutional Plan provides an overview of the Lawrence Berkeley Laboratory mission, strategic plan, scientific initiatives, research programs, environment and safety program plans, educational and technology transfer efforts, human resources, and facilities needs. The Strategic Plan section identifies long-range conditions that can influence the Laboratory, potential research trends, and several management implications. The Initiatives section identifies potential new research programs that represent major long-term opportunities for the Laboratory and the resources required for their implementation. The Scientific and Technical Programs section summarizes current programs and potential changes in research program activity. The Environment, Safety, and Health section describesmore » the management systems and programs underway at the Laboratory to protect the environment, the public, and the employees. The Technology Transfer and Education programs section describes current and planned programs to enhance the nation's scientific literacy and human infrastructure and to improve economic competitiveness. The Human Resources section identifies LBL staff composition and development programs. The section on Site and Facilities discusses resources required to sustain and improve the physical plant and its equipment. The Resource Projections are estimates of required budgetary authority for the Laboratory's ongoing research programs. The plan is an institutional management report for integration with the Department of Energy's strategic planning activities that is developed through an annual planning process. The plan identifies technical and administrative directions in the context of the National Energy Strategy and the Department of Energy's program planning initiatives. Preparation of the plan is coordinated by the Office for Planning and Development from information contributed by the Laboratory's scientific and support divisions.« less

Spacecraft System Failures and Anomalies Attributed to the Natural Space Environment

NASA Technical Reports Server (NTRS)

Bedingfield, Keith, L.; Leach, Richard D.; Alexander, Margaret B. (Editor)

1996-01-01

The natural space environment is characterized by many complex and subtle phenomena hostile to spacecraft. The effects of these phenomena impact spacecraft design, development, and operations. Space systems become increasingly susceptible to the space environment as use of composite materials and smaller, faster electronics increases. This trend makes an understanding of the natural space environment essential to accomplish overall mission objectives, especially in the current climate of better/cheaper/faster. This primer provides a brief overview of the natural space environment - definition, related programmatic issues, and effects on various spacecraft subsystems. The primary focus, however, is to catalog, through representative case histories, spacecraft failures and anomalies attributed to the natural space environment. This primer is one in a series of NASA Reference Publications currently being developed by the Electromagnetics and Aerospace Environments Branch, Systems Analysis and Integration Laboratory, Marshall Space Flight Center (MSFC), National Aeronautics and Space Administration (NASA).

A professional development model for medical laboratory scientists working in the immunohematology laboratory.

PubMed

Garza, Melinda N; Pulido, Lila A; Amerson, Megan; Ali, Faheem A; Greenhill, Brandy A; Griffin, Gary; Alvarez, Enrique; Whatley, Marsha; Hu, Peter C

2012-01-01

Transfusion medicine, a section of the Department of Laboratory Medicine at The University of Texas MD Anderson Cancer Center is committed to the education and advancement of its health care professionals. It is our belief that giving medical laboratory professionals a path for advancement leads to excellence and increases overall professionalism in the Immunohematology Laboratory. As a result of this strong commitment to excellence and professionalism, the Immunohematology laboratory has instituted a Professional Development Model (PDM) that aims to create Medical Laboratory Scientists (MLS) that are not only more knowledgeable, but are continually striving for excellence. In addition, these MLS are poised for advancement in their careers. The professional development model consists of four levels: Discovery, Application, Maturation, and Expert. The model was formulated to serve as a detailed path to the mastery of all process and methods in the Immunohematology Laboratory. Each level in the professional development model consists of tasks that optimize the laboratory workflow and allow for concurrent training. Completion of a level in the PDM is rewarded with financial incentive and further advancement in the field. The PDM for Medical Laboratory Scientists in the Immunohematology Laboratory fosters personal development, rewards growth and competency, and sets high standards for all services and skills provided. This model is a vital component of the Immunohematology Laboratory and aims to ensure the highest quality of care and standards in their testing. It is because of the success of this model and the robustness of its content that we hope other medical laboratories aim to reach the same level of excellence and professionalism, and adapt this model into their own environment.

Insights: Future of the national laboratories. National Renewable Energy Laboratory. [The future of the National Renewable Energy (Sources) Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sunderman, D.

Psychologists tell us that people are born with certain personality traits, such as shyness or boldness, which their environment can encourage, subdue, or even alter. National labs have somewhat similar characteristics. They were created for particular missions and staffed by people who built organizations in which those missions could be fulfilled. As a result, the Department of Energy's (DOE) national labs are among the world's finest repositories of technology and scientific talent, especially in the fields of defense, nuclear weapons, nuclear power, and basic energy. Sunderman, director of the National Renewable Energy Laboratory, discusses the history of the laboratory andmore » its place in the future, both in terms of technologies and nurturing.« less

HUMAN HEALTH RESEARCH IMPLEMENTATION PLAN, NATIONAL HEALTH AND ENVIRONMENTAL EFFECTS RESEARCH LABORATORY

EPA Science Inventory

The National Health and Environmental Effects Research Laboratory (NHEERL), as part of the Environmental Protection Agency's (EPA's) Office of Research and Development (ORD), is responsible for conducting research to improve the risk assessment of chemicals for potential effects ...

Marketing skills for hospital-based laboratory managers in a managed care environment.

PubMed

Marchwinski, J; Coggins, F

1997-01-01

Managers of hospital-based laboratories have begun to realize the importance of a successful outreach program in protecting against declining inpatient activity. Succeeding in the highly competitive field of outpatient testing requires some new skills and techniques that may not have been apparent when addressing normal inpatient requirements. This article provides an overview of some very basic marketing concepts and attempts to show how they can assist the hospital-based laboratory manager in developing a successful outreach program.

The physical environment mediates male harm and its effect on selection in females.

PubMed

Yun, Li; Chen, Patrick J; Singh, Amardeep; Agrawal, Aneil F; Rundle, Howard D

2017-07-12

Recent experiments indicate that male preferential harassment of high-quality females reduces the variance in female fitness, thereby weakening natural selection through females and hampering adaptation and purging. We propose that this phenomenon, which results from a combination of male choice and male-induced harm, should be mediated by the physical environment in which intersexual interactions occur. Using Drosophila melanogaster , we examined intersexual interactions in small and simple (standard fly vials) versus slightly more realistic (small cages with spatial structure) environments. We show that in these more realistic environments, sexual interactions are less frequent, are no longer biased towards high-quality females, and that overall male harm is reduced. Next, we examine the selective advantage of high- over low-quality females while manipulating the opportunity for male choice. Male choice weakens the viability advantage of high-quality females in the simple environment, consistent with previous work, but strengthens selection on females in the more realistic environment. Laboratory studies in simple environments have strongly shaped our understanding of sexual conflict but may provide biased insight. Our results suggest that the physical environment plays a key role in the evolutionary consequences of sexual interactions and ultimately the alignment of natural and sexual selection. © 2017 The Author(s).

Can MOND type hypotheses be tested in a free fall laboratory environment?

NASA Astrophysics Data System (ADS)

Das, Saurya; Patitsas, S. N.

2013-05-01

The extremely small accelerations of objects required for the onset of modified Newtonian dynamics, or modified Newtonian dynamics (MOND), makes testing the hypothesis in conventional terrestrial laboratories virtually impossible. This is due to the large background acceleration of Earth, which is transmitted to the acceleration of test objects within an apparatus. We show, however, that it may be possible to test MOND-type hypotheses with experiments using a conventional apparatus capable of tracking very small accelerations of its components but performed in locally inertial frames such as artificial satellites and other freely falling laboratories. For example, experiments involving an optical interferometer or a torsion balance in these laboratories would show nonlinear dynamics and displacement amplitudes larger than expected. These experiments may also be able to test potential violations of the strong equivalence principle by MOND and to distinguish between its two possible interpretations (modified inertia and modified gravity).

Adaptive Value of Phenological Traits in Stressful Environments: Predictions Based on Seed Production and Laboratory Natural Selection

PubMed Central

Glorieux, Cédric; Cuguen, Joel; Roux, Fabrice

2012-01-01

Phenological traits often show variation within and among natural populations of annual plants. Nevertheless, the adaptive value of post-anthesis traits is seldom tested. In this study, we estimated the adaptive values of pre- and post-anthesis traits in two stressful environments (water stress and interspecific competition), using the selfing annual species Arabidopsis thaliana. By estimating seed production and by performing laboratory natural selection (LNS), we assessed the strength and nature (directional, disruptive and stabilizing) of selection acting on phenological traits in A. thaliana under the two tested stress conditions, each with four intensities. Both the type of stress and its intensity affected the strength and nature of selection, as did genetic constraints among phenological traits. Under water stress, both experimental approaches demonstrated directional selection for a shorter life cycle, although bolting time imposes a genetic constraint on the length of the interval between bolting and anthesis. Under interspecific competition, results from the two experimental approaches showed discrepancies. Estimation of seed production predicted directional selection toward early pre-anthesis traits and long post-anthesis periods. In contrast, the LNS approach suggested neutrality for all phenological traits. This study opens questions on adaptation in complex natural environment where many selective pressures act simultaneously. PMID:22403624

An Accident Prevention Program for School Shops and Laboratories; A Suggested Guide for School Administrators.

ERIC Educational Resources Information Center

Williams, William A.

Effective and realistic planning and improvement of the educational environment can prevent accidents and injuries in school shops and laboratories. This guide makes specific recommendations for organizing and administering such a program and suggests methods and techniques for implementing the recommendations. Chapters cover organizing,…

Cost-effectiveness of forced air warming during sedation in the cardiac catheterisation laboratory.

PubMed

Conway, Aaron; Duff, Jed; Sutherland, Joanna

2018-05-13

To determine the cost-effectiveness of forced air warming during sedation in a cardiac catheterisation laboratory. Forced air warming improves thermal comfort in comparison with standard care. It is not known whether the extra costs required for forced air warming are good value. Cost-effectiveness analysis alongside a randomised controlled trial conducted in 2016-2017. A cost-effectiveness analysis was undertaken using Monte Carlo simulations from input distributions to estimate costs and effects associated with using forced air warming to reduce risk of thermal discomfort for patients receiving sedation in a cardiac catheterisation laboratory. A range of willingness to pay threshold values were tested with results plotted on a cost-effectiveness acceptability curve. Costs were calculated in Australian currency ($AUD). Estimated total costs were $5.21 (SD 3.26) higher per patient for forced air warming in comparison to standard care. Estimated probability of success (rating of thermal comfort) was 0.16 (0.06) higher for forced air warming. Forced air warming becomes more likely to result in a net benefit than standard care at a willingness to pay threshold of $34. Forced air warming could be considered cost-effective for procedures performed with sedation in a cardiac catheterisation laboratory if the extra cost of an incremental gain in thermal comfort is less than the decision maker's willingness to pay for it. Therefore, those responsible for decision-making regarding use of forced air warming in the cardiac catheterisation laboratory can use results of our model to decide if it represents good value for their organisation. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Laboratory Studies of Charging Properties of Dust Grains in Astrophysical/Planetary Environments

NASA Technical Reports Server (NTRS)

Tankosic, D.; Abbas, M. M.

2012-01-01

Dust grains in various astrophysical environments are generally charged electrostatically by photoelectric emissions with UV/X-ray radiation, as well as by electron/ion impact. Knowledge of physical and optical properties of individual dust grains is required for understanding of the physical and dynamical processes in space environments and the role of dust in formation of stellar and planetary systems. In this paper we focus on charging of individual micron/submicron dust grains by processes that include: (a) UV photoelectric emissions involving incident photon energies higher than the work function of the material and b) electron impact, where low energy electrons are scattered or stick to the dust grains, thereby charging the dust grains negatively, and at sufficiently high energies the incident electrons penetrate the grain leading to excitation and emission of electrons referred to as secondary electron emission (SEE). It is well accepted that the charging properties of individual micron/submicron size dust grains are expected to be substantially different from the bulk materials. However, no viable models for calculation of the charging properties of individual micron size dust grains are available at the present time. Therefore, the photoelectric yields, and secondary electron emission yields of micron-size dust grains have to be obtained by experimental methods. Currently, very limited experimental data are available for charging of individual micron-size dust grains. Our experimental results, obtained on individual, micron-size dust grains levitated in an electrodynamic balance facility (at NASA-MSFC), show that: (1) The measured photoelectric yields are substantially higher than the bulk values given in the literature and indicate a particle size dependence with larger particles having order-of-magnitude higher values than for submicron-size grains; (2) dust charging by low energy electron impact is a complex process. Also, our measurements indicate that

Laboratory Needs for Interstellar Ice Studies

NASA Astrophysics Data System (ADS)

Boogert, Abraham C. A.

2012-05-01

A large fraction of the molecules in dense interstellar and circumstellar environments is stored in icy grain mantles. The mantles are formed by a complex interplay between chemical and physical processes. Key questions on the accretion and desorption processes and the chemistry on the grain surfaces and within the icy mantles can only be answered by laboratory experiments. Recent infrared (2-30 micron) spectroscopic surveys of large samples of Young Stellar Objects (YSOs) and background stars tracing quiescent cloud material have shown that the ice band profiles and depths vary considerably as a function of environment. Using laboratory spectra in the identification process, it is clear that a rather complex mixture of simple species (CH3OH, CO2, H2O, CO) exists even in the quiescent cloud phase. Variations of the local physical conditions (CO freeze out) and time scales (CH3OH formation) appear to be key factors in the observed variations. Sublimation and thermal processing dominate as YSOs heat their environments. The identification of several ice absorption features is still disputed. I will outline laboratory work (e.g., on salts, PAHs, and aliphatic hydrocarbons) needed to further constrain the ice band identification as well as the thermal and chemical history of the carriers. Such experiments will also be essential to interpret future high spectral resolution SOFIA and JWST observations.

Laboratory Ventilation and Safety.

ERIC Educational Resources Information Center

Steere, Norman V.

1965-01-01

In order to meet the needs of both safety and economy, laboratory ventilation systems must effectively remove air-borne toxic and flammable materials and at the same time exhaust a minimum volume of air. Laboratory hoods are the most commonly used means of removing gases, dusts, mists, vapors, and fumed from laboratory operations. To be effective,…

Exploring Collaborative Learning Effect in Blended Learning Environments

ERIC Educational Resources Information Center

Sun, Z.; Liu, R.; Luo, L.; Wu, M.; Shi, C.

2017-01-01

The use of new technology encouraged exploration of the effectiveness and difference of collaborative learning in blended learning environments. This study investigated the social interactive network of students, level of knowledge building and perception level on usefulness in online and mobile collaborative learning environments in higher…

Lawrence Livermore National Laboratory environmental report for 1990

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sims, J.M.; Surano, K.A.; Lamson, K.C.

1990-01-01

This report documents the results of the Environmental Monitoring Program at the Lawrence Livermore National Laboratory (LLNL) and presents summary information about environmental compliance for 1990. To evaluate the effect of LLNL operations on the local environment, measurements of direct radiation and a variety of radionuclides and chemical compounds in ambient air, soil, sewage effluent surface water, groundwater, vegetation, and foodstuff were made at both the Livermore site and at Site 300 nearly. LLNL's compliance with all applicable guides, standards, and limits for radiological and nonradiological emissions to the environment was evaluated. Aside from an August 13 observation of silvermore » concentrations slightly above guidelines for discharges to the sanitary sewer, all the monitoring data demonstrated LLNL compliance with environmental laws and regulations governing emission and discharge of materials to the environment. In addition, the monitoring data demonstrated that the environmental impacts of LLNL are minimal and pose no threat to the public to or to the environment. 114 refs., 46 figs., 79 tabs.« less

Polish Code of Ethics of a Medical Laboratory Specialist

PubMed Central

2014-01-01

Along with the development of medicine, increasingly significant role has been played by the laboratory diagnostics. For over ten years the profession of the medical laboratory specialist has been regarded in Poland as the autonomous medical profession and has enjoyed a status of one of public trust. The process of education of medical laboratory specialists consists of a five-year degree in laboratory medicine, offered at Medical Universities, and of a five-year Vocational Specialization in one of the fields of laboratory medicine such as clinical biochemistry, medical microbiology, medical laboratory toxicology, medical laboratory cytomorphology and medical laboratory transfusiology. An important component of medical laboratory specialists’ identity is awareness of inherited ethos obtained from bygone generations of workers in this particular profession and the need to continue its further development. An expression of this awareness is among others Polish Code of Ethics of a Medical Laboratory Specialist (CEMLS) containing a set of values and a moral standpoint characteristic of this type of professional environment. Presenting the ethos of the medical laboratory specialist is a purpose of this article. Authors focus on the role CEMLS plays in areas of professional ethics and law. Next, they reconstruct the Polish model of ethos of medical diagnostic laboratory personnel. An overall picture consists of a presentation of the general moral principles concerning execution of this profession and rules of conduct in relations with the patient, own professional environment and the rest of the society. Polish model of ethical conduct, which is rooted in Hippocratic medical tradition, harmonizes with the ethos of medical laboratory specialists of other European countries and the world. PMID:27683468

Polish Code of Ethics of a Medical Laboratory Specialist.

PubMed

Elżbieta, Puacz; Waldemar, Glusiec; Barbara, Madej-Czerwonka

2014-09-01

Along with the development of medicine, increasingly significant role has been played by the laboratory diagnostics. For over ten years the profession of the medical laboratory specialist has been regarded in Poland as the autonomous medical profession and has enjoyed a status of one of public trust. The process of education of medical laboratory specialists consists of a five-year degree in laboratory medicine, offered at Medical Universities, and of a five-year Vocational Specialization in one of the fields of laboratory medicine such as clinical biochemistry, medical microbiology, medical laboratory toxicology, medical laboratory cytomorphology and medical laboratory transfusiology. An important component of medical laboratory specialists' identity is awareness of inherited ethos obtained from bygone generations of workers in this particular profession and the need to continue its further development. An expression of this awareness is among others Polish Code of Ethics of a Medical Laboratory Specialist (CEMLS) containing a set of values and a moral standpoint characteristic of this type of professional environment. Presenting the ethos of the medical laboratory specialist is a purpose of this article. Authors focus on the role CEMLS plays in areas of professional ethics and law. Next, they reconstruct the Polish model of ethos of medical diagnostic laboratory personnel. An overall picture consists of a presentation of the general moral principles concerning execution of this profession and rules of conduct in relations with the patient, own professional environment and the rest of the society. Polish model of ethical conduct, which is rooted in Hippocratic medical tradition, harmonizes with the ethos of medical laboratory specialists of other European countries and the world.

Follow-up on the effects of the space environment on UHCRE thermal blankets

NASA Technical Reports Server (NTRS)

Levadou, Francois; Vaneesbeek, Marc

1993-01-01

An overview of the effects of the space environment on the thermal blanket of the UHCRE experiment is presented with an emphasis on atomic oxygen (AO) erosion. A more accurate value for FEP Teflon reaction efficiency is given and corresponds, at normal incidence, to 3.24 10(exp -25) cu cm/atomic, therefore, the FEP Teflon erosion corresponding to the Long Duration Exposure Facility (LDEF) total mission is 29.5 microns. A power 1.44 of the cosine of the incident angle of the oxygen atoms is found. It is shown that this value is not far from the power found using Fergusson's relationship between efficiency and energy of the O-atoms. An hypothesis concerning the effect of oxygen ions (O(+)) is also presented. The presence of oxygen ions may explain the different results obtained from different flights and from laboratory tests. Finally an XPS analysis of Chemglaze Z306(tm) black paint demonstrates the presence of silicone in the paint which may explain part of the contamination found on LDEF.

Inquiring Scaffolds in Laboratory Tasks: An Instance of a "Worked Laboratory Guide Effect"?

ERIC Educational Resources Information Center

Schmidt-Borcherding, Florian; Hänze, Martin; Wodzinski, Rita; Rincke, Karsten

2013-01-01

The study explores if established support devices for paper-pencil problem solving, namely worked examples and incremental scaffolds, are applicable to laboratory tasks. N?=?173 grade eight students solved in dyads a physics laboratory task in one of three conditions. In condition A (unguided problem solving), students were asked to determine the…

Effect-directed analysis supporting monitoring of aquatic environments--An in-depth overview.

PubMed

Brack, Werner; Ait-Aissa, Selim; Burgess, Robert M; Busch, Wibke; Creusot, Nicolas; Di Paolo, Carolina; Escher, Beate I; Mark Hewitt, L; Hilscherova, Klara; Hollender, Juliane; Hollert, Henner; Jonker, Willem; Kool, Jeroen; Lamoree, Marja; Muschket, Matthias; Neumann, Steffen; Rostkowski, Pawel; Ruttkies, Christoph; Schollee, Jennifer; Schymanski, Emma L; Schulze, Tobias; Seiler, Thomas-Benjamin; Tindall, Andrew J; De Aragão Umbuzeiro, Gisela; Vrana, Branislav; Krauss, Martin

2016-02-15

Aquatic environments are often contaminated with complex mixtures of chemicals that may pose a risk to ecosystems and human health. This contamination cannot be addressed with target analysis alone but tools are required to reduce this complexity and identify those chemicals that might cause adverse effects. Effect-directed analysis (EDA) is designed to meet this challenge and faces increasing interest in water and sediment quality monitoring. Thus, the present paper summarizes current experience with the EDA approach and the tools required, and provides practical advice on their application. The paper highlights the need for proper problem formulation and gives general advice for study design. As the EDA approach is directed by toxicity, basic principles for the selection of bioassays are given as well as a comprehensive compilation of appropriate assays, including their strengths and weaknesses. A specific focus is given to strategies for sampling, extraction and bioassay dosing since they strongly impact prioritization of toxicants in EDA. Reduction of sample complexity mainly relies on fractionation procedures, which are discussed in this paper, including quality assurance and quality control. Automated combinations of fractionation, biotesting and chemical analysis using so-called hyphenated tools can enhance the throughput and might reduce the risk of artifacts in laboratory work. The key to determining the chemical structures causing effects is analytical toxicant identification. The latest approaches, tools, software and databases for target-, suspect and non-target screening as well as unknown identification are discussed together with analytical and toxicological confirmation approaches. A better understanding of optimal use and combination of EDA tools will help to design efficient and successful toxicant identification studies in the context of quality monitoring in multiply stressed environments. Copyright © 2015 Elsevier B.V. All rights reserved.

Computer Networks as Instructional and Collaborative Distance Learning Environments.

ERIC Educational Resources Information Center

Schrum, Lynne; Lamb, Theodore A.

1997-01-01

Reports on the early stages of a project at the U.S. Air Force Academy, in which the instructional applications of a networked classroom laboratory, an intranet, and the Internet are explored as well as the effectiveness and efficiency of groupware and computer networks as instructional environments. Presents the results of the first pilot tests.…

Aerothermodynamic Design of the Mars Science Laboratory Heatshield

NASA Technical Reports Server (NTRS)

Edquist, Karl T.; Dyakonov, Artem A.; Wright, Michael J.; Tang, Chun Y.

2009-01-01

Aerothermodynamic design environments are presented for the Mars Science Laboratory entry capsule heatshield. The design conditions are based on Navier-Stokes flowfield simulations on shallow (maximum total heat load) and steep (maximum heat flux, shear stress, and pressure) entry trajectories from a 2009 launch. Boundary layer transition is expected prior to peak heat flux, a first for Mars entry, and the heatshield environments were defined for a fully-turbulent heat pulse. The effects of distributed surface roughness on turbulent heat flux and shear stress peaks are included using empirical correlations. Additional biases and uncertainties are based on computational model comparisons with experimental data and sensitivity studies. The peak design conditions are 197 W/sq cm for heat flux, 471 Pa for shear stress, 0.371 Earth atm for pressure, and 5477 J/sq cm for total heat load. Time-varying conditions at fixed heatshield locations were generated for thermal protection system analysis and flight instrumentation development. Finally, the aerothermodynamic effects of delaying launch until 2011 are previewed.

Pacific Northwest Laboratory annual report for 1979 to the DOE Assistant Secretary for Environment. Part 5. Environmental assessment, control, health, and safety

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baalman, R.W.; Dotson, C.W.

1980-02-01

Part 5 of the 1979 Annual Report to the Department of Energy Assistant Secretary for the Environment presents Pacific Northwest Laboratory's progress on work performed for the Office of Technology Impacts, the Office of Environmental Compliance and Overview, and the Office of Health and Environmental Research. The report is in four sections, corresponding to the program elements: technology impacts, environmental control engineering, operational and environmental compliance, and human health studies. In each section, articles describe progress made during FY 1979 on individual projects.

Internet, Multimedia and Virtual Laboratories in a 'Third World' Environment.

ERIC Educational Resources Information Center

Monge-Najera, Julian Antonio; Rivas Rossi, Marta; Mendez-Estrada, Victor Hugo

2001-01-01

Describes the development of low-cost multimedia courses and materials for use on the Internet, as well as virtual laboratories, at the Universidad Estatal a Distancia (Costa Rica). Explains how simultaneous production of traditional printed materials and online courses, outsourcing, and the use of HTML and Java can reduce costs for developing…

Occurrence and effects of plastic additives on marine environments and organisms: A review.

PubMed

Hermabessiere, Ludovic; Dehaut, Alexandre; Paul-Pont, Ika; Lacroix, Camille; Jezequel, Ronan; Soudant, Philippe; Duflos, Guillaume

2017-09-01

Plastics debris, especially microplastics, have been found worldwide in all marine compartments. Much research has been carried out on adsorbed pollutants on plastic pieces and hydrophobic organic compounds (HOC) associated with microplastics. However, only a few studies have focused on plastic additives. These chemicals are incorporated into plastics from which they can leach out as most of them are not chemically bound. As a consequence of plastic accumulation and fragmentation in oceans, plastic additives could represent an increasing ecotoxicological risk for marine organisms. The present work reviewed the main class of plastic additives identified in the literature, their occurrence in the marine environment, as well as their effects on and transfers to marine organisms. This work identified polybrominated diphenyl ethers (PBDE), phthalates, nonylphenols (NP), bisphenol A (BPA) and antioxidants as the most common plastic additives found in marine environments. Moreover, transfer of these plastic additives to marine organisms has been demonstrated both in laboratory and field studies. Upcoming research focusing on the toxicity of microplastics should include these plastic additives as potential hazards for marine organisms, and a greater focus on the transport and fate of plastic additives is now required considering that these chemicals may easily leach out from plastics. Copyright © 2017 Elsevier Ltd. All rights reserved.

Development of veterinary laboratory networks for avian influenza and other emerging infectious disease control: the southeast asian experience.

PubMed

Daniels, Peter; Poermadjaja, Bagoes; Morrissy, Chris; Ngo, Thanh Long; Selleck, Paul; Kalpravidh, Wantanee; Weaver, John; Wong, Frank; Torchetti, Mia Kim; Allen, John; Padungtod, Parwin; Davis, Andrew; Suradhat, Sanipa; Morzaria, Subhash

2014-01-01

The outbreak of highly pathogenic H5N1 avian influenza, with its international spread, confirmed that emerging infectious disease control must be underpinned by effective laboratory services. Laboratory results are the essential data underpinning effective surveillance, case diagnosis, or monitoring of responses. Importantly, laboratories are best managed within national and international networks of technological support rather than in isolation. A well planned laboratory network can deliver both a geographical spread of testing capacity and also a cost effective hierarchy of capability. Hence in the international context regional networks can be particularly effective. Laboratories are an integral part of a country's veterinary services and their role and function should be clearly defined in the national animal health strategy and supporting government policies. Not every laboratory should be expected to deliver every possible service, and integration into regional and broader international networks should be a part of the overall strategy. The outputs required of each laboratory should be defined and then ensured through accredited quality assurance. The political and scientific environment in which laboratories operate changes continuously, not only through evolving national and regional animal health priorities but also through new test technologies and enhancements to existing technologies. Active networks help individual laboratories to monitor, evaluate, and respond to such challenges and opportunities. The end result is enhanced emerging infectious disease preparedness across the region.

NASA's Space Environments and Effects (SEE) program: contamination engineering technology development

NASA Astrophysics Data System (ADS)

Pearson, Steven D.; Clifton, K. Stuart

1999-10-01

The return of the Long Duration Exposure Facility (LDEF) in 1990 brought a wealth of space exposure data on materials, paints, solar cells, etc. and data on the many space environments. The effects of the harsh space environments can provide damaging or even disabling effects on spacecraft, its materials, and its instruments. In partnership with industry, academia, and other government agencies, National Aeronautics & Space Administration's (NASA's) Space Environments & Effects (SEE) Program defines the space environments and provides technology development to accommodate or mitigate these harmful environments on the spacecraft. This program provides a very comprehensive and focused approach to understanding the space environment, to define the best techniques for both flight and ground-based experimentation, to update the models which predict both the environments and the environmental effects on spacecraft, and finally to ensure that this information is properly maintained and inserted into spacecraft design programs. This paper will describe the current SEE Program and will present SEE contamination engineering technology development and risk mitigation for future spacecraft design.

NASA's Space Environments and Effects (SEE) Program: Contamination Engineering Technology Development

NASA Technical Reports Server (NTRS)

Pearson, Steven D.; Clifton, K. Stuart

1999-01-01

ABSTRACT The return of the Long Duration Exposure Facility (LDEF) in 1990 brought a wealth of space exposure data on materials, paints, solar cells, etc. and data on the many space environments. The effects of the harsh space environments can provide damaging or even disabling effects on spacecraft, its materials, and its instruments. In partnership with industry, academia, and other government agencies, National Aeronautics & Space Administration's (NASA's) Space Environments & Effects (SEE) Program defines the space environments and provides technology development to accommodate or mitigate these harmful environments on the spacecraft. This program provides a very comprehensive and focused approach to understanding the space environment, to define the best techniques for both flight and ground-based experimentation, to update the models which predict both the environments and the environmental effects on spacecraft, and finally to ensure that this information is properly maintained and inserted into spacecraft design programs. This paper will describe the current SEE Program and will present SEE contamination engineering technology development and risk mitigation for future spacecraft design.

Fine Sediment Effects on Brook Trout Eggs in Laboratory Streams

Treesearch

David G. Argent; Patricia A. Flebbe

1999-01-01

This study was designed to determine effects of different fine sediments (0.43-0.85 mm in diameter) on survival of brook trout (Salvelinus fontinalis) eggs during early developmental stages under laboratory conditions. Intragravel permeability and dissolved oxygen declined with increasing fine sediment amounts. Survival at each developmental stage...

Sensitisation to Aspergillus fumigatus and Penicillium notatum in laboratory workers.

PubMed

Boscolo, P; Piccolomini, R; Benvenuti, F; Catamo, G; Di Gioacchino, M

1999-01-01

Four workers in medical research laboratories, located in a basement level of a University facility equipped with a humidified air conditioning system, complained of cough and/or asthma and/or rhinitis during their normal working activities. Since exposure to toxic compounds was very low (similar to that of the outdoor environment) only microbiological monitoring was performed. Aspergillus fumigatus and Penicillium notatum were found in some laboratories. Eight laboratory workers (including the 4 symptomatic subjects) out of 26 investigated were found to be atopic. Specific IgE sensitisation to Aspergillus fumigatus was found in the 8 atopic and in the 6 non-atopic workers, while Penicililum notatum was found in 7 atopic and 4 non-atopic subjects. History, physical examination and laboratory data excluded the presence of aspergillosis or allergic bronchial aspergillosis in the sensitised subjects. Our results suggest that evaluation of immune parameters, along with monitoring of the working environment, may reduce the risk of sensitisation and/or allergic symptoms in atopic laboratory workers.

Application of peer instruction in the laboratory task of measuring the effective mass of a spring

NASA Astrophysics Data System (ADS)

Zhang, Chun-Ling; Hou, Zhen-Yu; Si, Yu-Chang; Wen, Xiao-Qing; Tang, Lei

2017-11-01

Peer instruction (PI) is an effective interactive approach to teaching and learning that has principally been used to modify the experience of learning in traditional physics lecture settings. This article further illustrates how the concept of PI can be effectively applied in the physics student laboratory setting. The setting used is a laboratory task that calls for the measurement of the effective mass of the spring of a Jolly balance. Through PI the students gain a better understanding of what is meant by the construct ‘effective mass of a spring’, and thereby competently work out how the mass, shape, wire diameter, and number of turns of the spring can all affect the effective mass of the spring. Furthermore, using stopwatches the students were also able to appreciate how recorded times at the equilibrium position had greater uncertainty than measurements made at the maximum displacement. This led to their calculations of the effective mass of the spring being impressively close to the theoretical value. Such laboratory tasks are extremely challenging to introductory level students and the success attained by the students in this study indicates that there is much potential in the application of PI in laboratory settings. PI should be used to teach in the laboratory and results should be reported in order for our community to build on these experiences. This article is a contribution to that effort.

Safety and health practice among laboratory staff in Malaysian education sector

NASA Astrophysics Data System (ADS)

Husna Che Hassan, Nurul; Rasdan Ismail, Ahmad; Kamilah Makhtar, Nor; Azwadi Sulaiman, Muhammad; Syuhadah Subki, Noor; Adilah Hamzah, Noor

2017-10-01

Safety is the most important issue in industrial sector such as construction and manufacturing. Recently, the increasing number of accident cases reported involving school environment shows the important of safety issues in education sector. Safety awareness among staff in this sector is crucial in order to find out the method to prevent the accident occurred in future. This study was conducted to analyze the knowledge of laboratory staff in term of safety and health practice in laboratory. Survey questionnaires were distributing among 255 of staff laboratory from ten District Education Offices in Kelantan. Descriptive analysis shows that the understanding of safety and health practice are low while doing some job activities in laboratory. Furthermore, some of the staff also did not implemented safety practice that may contribute to unplanned event occur in laboratory. Suggestion that the staff at laboratory need to undergo on Occupational Safety and Health training to maintain and create safe environment in workplaces.

Untangling elevation-related differences in the hippocampus in food-caching mountain chickadees: the effect of a uniform captive environment.

PubMed

Freas, C A; Bingman, K; Ladage, L D; Pravosudov, V V

2013-01-01

Variation in environmental conditions associated with differential selection on spatial memory has been hypothesized to result in evolutionary changes in the morphology of the hippocampus, a brain region involved in spatial memory. At the same time, it is well known that the morphology of the hippocampus might also be directly affected by environmental conditions. Understanding the role of environment-based plasticity is therefore critical when investigating potential adaptive evolutionary changes in the hippocampus associated with environmental variation. We previously demonstrated large elevation-related variation in hippocampus morphology in mountain chickadees over an extremely small spatial scale. We hypothesized that this variation is related to differential selection pressures associated with differences in winter climate severity along an elevation gradient, which make different demands on spatial memory used for food cache retrieval. Here, we tested whether such variation is experience based, generated by potential differences in the environment, by comparing the hippocampus morphology of chickadees from different elevations maintained in a uniform captive environment in a laboratory with those sampled directly from the wild. In addition, we compared hippocampal neuron soma size in chickadees sampled directly from the wild with those maintained in laboratory conditions with restricted and unrestricted spatial memory use via manipulation of food-caching experiences to test whether memory use can affect neuron soma size. There were significant elevation-related differences in hippocampus volume and the total number of hippocampal neurons, but not in neuron soma size, in captive birds. Captive environmental conditions were associated with a large reduction in hippocampus volume and neuron soma size, but not in the total number of neurons or in neuron soma size in other telencephalic regions. Restriction of memory use while in laboratory conditions produced no

Increase Workshop | Argonne National Laboratory

Science.gov Websites

Skip to main content Argonne National Laboratory Toggle Navigation Toggle Search Home Learning solvers Home Learning Center Undergraduates Graduates Faculty Partners News & Events Faculty Visiting Us Argonne Educational Programs is committed to providing a learning environment that emphasizes the

Designing experiments on thermal interactions by secondary-school students in a simulated laboratory environment

NASA Astrophysics Data System (ADS)

Lefkos, Ioannis; Psillos, Dimitris; Hatzikraniotis, Euripides

2011-07-01

Background and purpose: The aim of this study was to explore the effect of investigative activities with manipulations in a virtual laboratory on students' ability to design experiments. Sample Fourteen students in a lower secondary school in Greece attended a teaching sequence on thermal phenomena based on the use of information and communication technology, and specifically of the simulated virtual laboratory 'ThermoLab'. Design and methods A pre-post comparison was applied. Students' design of experiments was rated in eight dimensions; namely, hypothesis forming and verification, selection of variables, initial conditions, device settings, materials and devices used, process and phenomena description. A three-level ranking scheme was employed for the evaluation of students' answers in each dimension. Results A Wilcoxon signed-rank test revealed a statistically significant difference between the students' pre- and post-test scores. Additional analysis by comparing the pre- and post-test scores using the Hake gain showed high gains in all but one dimension, which suggests that this improvement was almost inclusive. Conclusions We consider that our findings support the statement that there was an improvement in students' ability to design experiments.

Procurement of information systems effectively (POISE): using the new UK guidelines to purchase an integrated clinical laboratory system.

PubMed

Feltham, R K

1995-01-01

Open tendering for medical informatics systems in the UK has traditionally been lengthy and, therefore, expensive on resources for vendor and purchaser alike. Events in the United Kingdom (UK) and European Community (EC) have led to new Government guidance being published on procuring information systems for the public sector: Procurement of Information Systems Effectively (POISE). This innovative procurement process, launched in 1993, has the support of the Computing Services Association (CSA) and the Federation of the Electronics Industry (FEI). This paper gives an overview of these new UK guidelines on healthcare information system purchasing in the context of a recent procurement project with an NHS Trust Hospital. The aim of the project was to replace three aging, separate, and different laboratory computer systems with a new, integrated turnkey system offering all department modules, an Open modern computer environment, and on-line electronic links to key departmental systems, both within and external to the Trust by the end of 1994. The new system had to complement the Trust's strategy for providing a modern clinical laboratory service to the local population and meet a tight budget.

Environmental Regulation of Plant Gene Expression: An Rt-qPCR Laboratory Project for an Upper-Level Undergraduate Biochemistry or Molecular Biology Course

ERIC Educational Resources Information Center

Eickelberg, Garrett J.; Fisher, Alison J.

2013-01-01

We present a novel laboratory project employing "real-time" RT-qPCR to measure the effect of environment on the expression of the "FLOWERING LOCUS C" gene, a key regulator of floral timing in "Arabidopsis thaliana" plants. The project requires four 3-hr laboratory sessions and is aimed at upper-level undergraduate…

Laboratory evaluation of the pointing stability of the ASPS Vernier System

NASA Technical Reports Server (NTRS)

1980-01-01

The annular suspension and pointing system (ASPS) is an end-mount experiment pointing system designed for use in the space shuttle. The results of the ASPS Vernier System (AVS) pointing stability tests conducted in a laboratory environment are documented. A simulated zero-G suspension was used to support the test payload in the laboratory. The AVS and the suspension were modelled and incorporated into a simulation of the laboratory test. Error sources were identified and pointing stability sensitivities were determined via simulation. Statistical predictions of laboratory test performance were derived and compared to actual laboratory test results. The predicted mean pointing stability during simulated shuttle disturbances was 1.22 arc seconds; the actual mean laboratory test pointing stability was 1.36 arc seconds. The successful prediction of laboratory test results provides increased confidence in the analytical understanding of the AVS magnetic bearing technology and allows confident prediction of in-flight performance. Computer simulations of ASPS, operating in the shuttle disturbance environment, predict in-flight pointing stability errors less than 0.01 arc seconds.

Laboratory Spectroscopy of Large Carbon Molecules and Ions in Support of Space Missions. A New Generation of Laboratory & Space Studies

NASA Technical Reports Server (NTRS)

Salama, Farid; Tan, Xiaofeng; Cami, Jan; Biennier, Ludovic; Remy, Jerome

2006-01-01

Polycyclic Aromatic Hydrocarbons (PAHs) are an important and ubiquitous component of carbon-bearing materials in space. A long-standing and major challenge for laboratory astrophysics has been to measure the spectra of large carbon molecules in laboratory environments that mimic (in a realistic way) the physical conditions that are associated with the interstellar emission and absorption regions [1]. This objective has been identified as one of the critical Laboratory Astrophysics objectives to optimize the data return from space missions [2]. An extensive laboratory program has been developed to assess the properties of PAHs in such environments and to describe how they influence the radiation and energy balance in space. We present and discuss the gas-phase electronic absorption spectra of neutral and ionized PAHs measured in the UV-Visible-NIR range in astrophysically relevant environments and discuss the implications for astrophysics [1]. The harsh physical conditions of the interstellar medium characterized by a low temperature, an absence of collisions and strong VUV radiation fields - have been simulated in the laboratory by associating a pulsed cavity ringdown spectrometer (CRDS) with a supersonic slit jet seeded with PAHs and an ionizing, penning-type, electronic discharge. We have measured for the {\\it first time} the spectra of a series of neutral [3,4] and ionized [5,6] interstellar PAHs analogs in the laboratory. An effort has also been attempted to quantify the mechanisms of ion and carbon nanoparticles production in the free jet expansion and to model our simulation of the diffuse interstellar medium in the laboratory [7]. These experiments provide {\\it unique} information on the spectra of free, large carbon-containing molecules and ions in the gas phase. We are now, for the first time, in the position to directly compare laboratory spectral data on free, cold, PAH ions and carbon nano-sized carbon particles with astronomical observations in the

Maximizing nursing staff development. The learning laboratory.

PubMed

Kleinknecht, M K; Hefferin, E A

1990-01-01

To survive in today's cost-conscious medical-center environment, nursing education must show how it contributes effectively to promoting and maintaining the currency and competency of nursing staff practice, the quality of patient care, and the overall functioning of the medical center. In the face of limited resources, nursing education increasingly must promote staff's self-assessment of their own knowledge and skill deficiencies and use of self-study mechanisms to meet established performance standards. This survey explored the current use of learning laboratory centers used by nursing education for maximizing staff access to and use of needed remedial and practice update learning opportunities.

Effect of cold indoor environment on physical performance of older women living in the community.

PubMed

Lindemann, Ulrich; Oksa, Juha; Skelton, Dawn A; Beyer, Nina; Klenk, Jochen; Zscheile, Julia; Becker, Clemens

2014-07-01

the effects of cold on older persons' body and mind are not well documented, but with an increased number of older people with decreasing physical performance, these possible effects need to be understood. to investigate the effect of cold indoor environment on physical performance of older women. cross-sectional experimental study with two test conditions. movement laboratory in a climate chamber. eighty-eight community-dwelling, cognitively unimpaired older women (mean age 78 years). participants were exposed to moderately cold (15°C) and warm/normal (25°C) temperature in a climate chamber in random order with an interval of 1 week. The assessment protocol included leg extensor power (Nottingham Power Rig), sit-to-stand performance velocity (linear encoder), gait speed, walk-ratio (i.e. step length/cadence on an instrumented walk way), maximal quadriceps and hand grip strength. physical performance was lower in 15°C room temperature compared with 25°C room temperature for leg extensor power (P < 0.0001), sit-to-stand performance velocity (P < 0.0001), gait speed (P < 0.0001), walk-ratio (P = 0.016) and maximal quadriceps strength (P = 0.015), but not for hand grip strength. in healthy older women a moderately cold indoor environment decreased important physical performance measures necessary for independent living. © The Author 2014. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Radiation effects in spacecraft electronics

NASA Technical Reports Server (NTRS)

Raymond, James P.

1989-01-01

Effects on the internal spacecraft electronics due to exposure to the natural and enhanced space radiation environment will be reviewed. The emphasis will be placed on the description of the nature of both the exposure environment and failure mechanisms in semiconductors. Understanding both the system environment and device effects is critical in the use of laboratory simulation environments to obtain the data necessary to design and qualify components for successful application.

Natural Pathogens of Laboratory Mice, Rats, and Rabbits and Their Effects on Research

PubMed Central

Baker, David G.

1998-01-01

Laboratory mice, rats, and rabbits may harbor a variety of viral, bacterial, parasitic, and fungal agents. Frequently, these organisms cause no overt signs of disease. However, many of the natural pathogens of these laboratory animals may alter host physiology, rendering the host unsuitable for many experimental uses. While the number and prevalence of these pathogens have declined considerably, many still turn up in laboratory animals and represent unwanted variables in research. Investigators using mice, rats, and rabbits in biomedical experimentation should be aware of the profound effects that many of these agents can have on research. PMID:9564563

Single Event Effects Test Facility Options at the Oak Ridge National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Riemer, Bernie; Gallmeier, Franz X; Dominik, Laura J

2015-01-01

Increasing use of microelectronics of ever diminishing feature size in avionics systems has led to a growing Single Event Effects (SEE) susceptibility arising from the highly ionizing interactions of cosmic rays and solar particles. Single event effects caused by atmospheric radiation have been recognized in recent years as a design issue for avionics equipment and systems. To ensure a system meets all its safety and reliability requirements, SEE induced upsets and potential system failures need to be considered, including testing of the components and systems in a neutron beam. Testing of integrated circuits (ICs) and systems for use in radiationmore » environments requires the utilization of highly advanced laboratory facilities that can run evaluations on microcircuits for the effects of radiation. This paper provides a background of the atmospheric radiation phenomenon and the resulting single event effects, including single event upset (SEU) and latch up conditions. A study investigating requirements for future single event effect irradiation test facilities and developing options at the Spallation Neutron Source (SNS) is summarized. The relatively new SNS with its 1.0 GeV proton beam, typical operation of 5000 h per year, expertise in spallation neutron sources, user program infrastructure, and decades of useful life ahead is well suited for hosting a world-class SEE test facility in North America. Emphasis was put on testing of large avionics systems while still providing tunable high flux irradiation conditions for component tests. Makers of ground-based systems would also be served well by these facilities. Three options are described; the most capable, flexible, and highest-test-capacity option is a new stand-alone target station using about one kW of proton beam power on a gas-cooled tungsten target, with dual test enclosures. Less expensive options are also described.« less

U.S. Laboratory

NASA Image and Video Library

2016-03-23

ISS047e016355 (03/23/2016) --- The International Space Station's Destiny Laboratory at “night” shortly before the Expedition 47 crew entered its scheduled sleep period. The space station experiences 16 sunrises and sunsets every day which can alter the crew’s circadian rhythm and disrupt sleep patterns. Lights are turned off and windows are covered to give the interior of the station a nighttime environment during sleep cycles.

The role of total laboratory automation in a consolidated laboratory network.

PubMed

Seaberg, R S; Stallone, R O; Statland, B E

2000-05-01

In an effort to reduce overall laboratory costs and improve overall laboratory efficiencies at all of its network hospitals, the North Shore-Long Island Health System recently established a Consolidated Laboratory Network with a Core Laboratory at its center. We established and implemented a centralized Core Laboratory designed around the Roche/Hitachi CLAS Total Laboratory Automation system to perform the general and esoteric laboratory testing throughout the system in a timely and cost-effective fashion. All remaining STAT testing will be performed within the Rapid Response Laboratories (RRLs) at each of the system's hospitals. Results for this laboratory consolidation and implementation effort demonstrated a decrease in labor costs and improved turnaround time (TAT) at the core laboratory. Anticipated system savings are approximately $2.7 million. TATs averaged 1.3 h within the Core Laboratory and less than 30 min in the RRLs. When properly implemented, automation systems can reduce overall laboratory expenses, enhance patient services, and address the overall concerns facing the laboratory today: job satisfaction, decreased length of stay, and safety. The financial savings realized are primarily a result of labor reductions.

Non-Stop Lab Week: A Real Laboratory Experience for Life Sciences Postgraduate Courses

ERIC Educational Resources Information Center

Freitas, Maria João; Silva, Joana Vieira; Korrodi-Gregório, Luís; Fardilha, Margarida

2016-01-01

At the Portuguese universities, practical classes of life sciences are usually professor-centered 2-hour classes. This approach results in students underprepared for a real work environment in a research/clinical laboratory. To provide students with a real-life laboratory environment, the Non-Stop Lab Week (NSLW) was created in the Molecular…

Altering BDNF expression by genetics and/or environment: impact for emotional and depression-like behaviour in laboratory mice.

PubMed

Chourbaji, Sabine; Brandwein, Christiane; Gass, Peter

2011-01-01

According to the "neurotrophin hypothesis", brain-derived neurotrophic factor (BDNF) is an important candidate gene in depression. Moreover, environmental stress is known to represent a risk factor in the pathophysiology and treatment of this disease. To elucidate, whether changes of BDNF availability signify cause or consequence of depressive-like alterations, it is essential to look for endophenotypes under distinct genetic conditions (e.g. altered BDNF expression). Furthermore it is crucial to examine environment-driven BDNF regulation and its effect on depressive-linked features. Consequently, gene × environment studies investigating prospective genetic mouse models of depression in different environmental contexts become increasingly important. The present review summarizes recent findings in BDNF-mutant mice, which have been controversially discussed as models of depression and anxiety. It furthermore illustrates the potential of environment to serve as naturalistic stressor with the potential to modulate the phenotype in wildtype and mutant mice. Moreover, environment may exert protective effects by regulating BDNF levels as attributed to "environmental enrichment". The effect of this beneficial condition will also be discussed with regard to probable "curative/therapeutic" approaches. Copyright © 2010 Elsevier Ltd. All rights reserved.

State of the research environment - 2013

DOE Office of Scientific and Technical Information (OSTI.GOV)

Phillips, Julia Mae; Simmons, Jerry Alvon; Weaver, Karla

2014-02-01

This report describes the condition of the research environment at Sandia National Laboratories and outlines key environment improvement activities undertaken by the Office of the Chief Technology Officer and the Sandia Research Leadership Team during fiscal year 2013. The report also outlines Lab-level objectives related to the research environment for fiscal year 2014.

Apel - Applied Process Engineering Laboratory

Science.gov Websites

startup and testing Equipment can be quickly connected to building services and effluent systems. A professional, regulated environment for bringing forth new product processes and services. Testing shortens the support Pacific Northwest National Laboratory (PNNL) scientists, engineers, and other professional staff

Internship Opportunities | Argonne National Laboratory

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Skip to main content Argonne National Laboratory Toggle Navigation Toggle Search Home Learning -class research to tomorrow's STEM problem solvers Home Learning Center Undergraduates Graduates Faculty ) 252-4114 Contact Us Argonne Educational Programs is committed to providing a learning environment that

[Biosafety and biosecurity in the medical laboratory. Update and trends].

PubMed

Ionescu, G; Neguţ, M; Combiescu, A A

2007-01-01

Biosafety includes the protective measures against the risks of contamination with pathogen germs in the laboratories that handle pathogens, or stock or manipulate potentially contaminated products, or perform microbiological tests for medical or scientific research purposes, as well as the means of protecting the environment and the human collectivities against hazard contaminations that have as starting point these laboratories. Besides, lately, a new notion emerged, that of biosecurity, which refers to the sum of measures designed to protect workers, environment and population against the loss, theft, use and release in the environment of pathogenic biological agents. The work overviews the present concerns for the regulation of these two notions and the way in which a system for the management of the biological risks in a laboratory that handles pathogens should be documented and implemented. The need for the continuous professional training of the staff and for the establishment of individual and collective responsibilities for preventing biosafety incidents and trespassing biosecurity rules are as well emphasized. The main biosafety measures are pointed out and a series of considerations regarding biosafety and bioterrorism in correlation with the medical laboratory are as well mentioned.

Micromachined probes for laboratory plasmas

NASA Astrophysics Data System (ADS)

Chiang, Franklin Changta

As we begin to find more applications for plasmas in our everyday lives, the ability to characterize and understand their inner workings becomes increasingly important. Much of our current understanding of plasma physics comes from investigations conducted in diffuse, outer space plasmas where experimenters have no control over the environment or experimental conditions and one measures interesting phenomena only by chance when the spacecraft or satellite passes through them. Ideally, experiments should be performed in a controlled environment, where plasma events can be deliberately and reliably created when wanted and probes placed precisely within the plasma. Unfortunately, often due to their size, probes used in outer space are unsuitable for use in high-density laboratory plasmas, and constructing probes that can be used in terrestrial plasmas is a considerable challenge. This dissertation presents the development, implementation, and experimental results of three micromachined probes capable of measuring voltage and electric field, ion energies, and changing magnetic fields (B-dot) in laboratory plasmas.

Differential evolution of asexual and sexual females in a benign culture environment

PubMed Central

Snell, Terry W.

2013-01-01

Here we report one of the first investigations of evolvability of lifespan and reproduction in metazoans, examining both extrinsic and intrinsic factors. We tested effects on senescence of an environmental variable (simulated lake hydroperiod, the length of time an aquatic habitat is inundated), female reproductive physiology (asexual females that reproduce by ameiosis, versus sexual females reproducing by meiosis), and time in a benign culture environment (minimal, if any, external mortality factors). To do this we established chemostat cultures of the rotifer Brachionus plicatilis s.s., and maintained the cultures for 385 d. Hydroperiod alone or in interaction with the effects of time in the benign environment (season) or reproductive physiology had no significant effect on the net reproductive rate, generation time, or rate of aging. Yet combining animals from both ephemeral and permanent hydroperiods revealed a 26% increase in asexual female lifespan across seasons (23% decrease in the rate of aging) and a 56% increase in asexual fecundity, suggesting that maintenance in benign laboratory conditions leads to slower aging. The relative stasis of traits for sexual females implies an impact of reproductive physiology on evolvability. In addition we found a positive correlation between fecundity and lifespan, suggesting an absence of trade-offs in life history traits in the benign laboratory environment. PMID:24795527

EFFECTS OF TEMPERATURE AND ENVIRONMENT ON MECHANICAL PROPERTIES OF TWO CHOPPED-FIBER AUTOMOTIVE STRUCTURAL COMPOSITES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ruggles-Wrenn, M.B.

2003-10-06

The Durability of Lightweight Composite Structures Project was established at Oak Ridge National Laboratory (ORNL) by the U.S. Department of Energy to provide the experimentally-based, durability-driven design guidelines necessary to assure long-term structural integrity of automotive composite components. The initial focus of the ORNL Durability Project was on composite materials consisting of polyurethane reinforced with E-glass. Current focus of the project is on composite materials reinforced with carbon fibers. The primary purpose of this report is to provide the individual specimen test date. Basic mechanical property testing and results for two chopped-fiber composite materials, one reinforced with glass- and themore » other with carbon fiber are provided. Both materials use the same polyurethane matrix. Preforms for both materials were produced using the P4 process. Behavioral trends, effects of temperature and environment, and corresponding design knockdown factors are established for both materials. Effects of prior short-time loads and of prior thermal cycling are discussed.« less

UK dental laboratory technicians' views on the efficacy and teaching of clinical-laboratory communication.

PubMed

Juszczyk, A S; Clark, R K F; Radford, D R

2009-05-23

The General Dental Council states that 'good dental care is delivered by a team' and restorative treatment is enhanced by communication between team members. Commercial dental laboratories are ideally placed to comment on effective communication. To investigate contemporary attitudes and communication between dentist and dental technician from the technician's perspective. Eight hundred and three dental laboratories were invited to take part in a postal survey covering dentist/laboratory communication and the dentist's understanding of technical procedures. Forty percent of laboratories responded. Only 9% scored communication as very good, 48% scored communication with newly qualified dentists better than with established dentists but only 26% considered that dental students were taught to communicate with dental laboratories effectively. The free comments that the respondents were invited to make identified three distinct themes, 'recognition within the dental team', 'effective communication between dentist and dental technician' and 'dentists lack of technical knowledge'. Effective communication between dentist and dental technician is often poor. It was the view of the dental technicians who responded that newly qualified dentists do not have an appropriate understanding of technical techniques. Dental schools are still not preparing new graduates to communicate effectively with dental laboratories.

Pacific Northwest Laboratory annual report for 1980 to the DOE Assistant Secretary for Environment. Part 5. Environmental assessment, control, health and safety

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baalman, R.W.; Hays, I.D.

1981-02-01

Pacific Northwest Laboratory's (PNL) 1980 annual report to the DOE Assistant Secretary for Environment describes research in environment, health, and safety conducted during fiscal year 1980. Part 5 includes technology assessments for natural gas, enhanced oil recovery, oil shale, uranium mining, magnetic fusion energy, solar energy, uranium enrichment and industrial energy utilization; regional analysis studies of environmental transport and community impacts; environmental and safety engineering for LNG, oil spills, LPG, shale oil waste waters, geothermal liquid waste disposal, compressed air energy storage, and nuclear/fusion fuel cycles; operational and environmental safety studies of decommissioning, environmental monitoring, personnel dosimetry, and analysis ofmore » criticality safety; health physics studies; and epidemiological studies. Also included are an author index, organization of PNL charts and distribution lists of the annual report, along with lists of presentations and publications. (DLS)« less

Behavior of steelhead fry in a laboratory stream is affected by fish density but not rearing environment

USGS Publications Warehouse

Riley, Stephen C.; Tatara, Christopher P.; Berejikian, Barry A.; Flagg, Thomas A.

2009-01-01

We quantified the aggression, feeding, dominance, position choice, and territory size of naturally reared steelhead Oncorhynchus mykiss fry stocked with two types of hatchery-reared fry (from conventional and enriched rearing environments) at two densities in experimental flumes to determine how rearing environment and fish density affect the behavior of steelhead fry. We found that fry density had a significant effect on most response variables but that rearing treatment did not. The rates of threats and attacks were positively correlated with fry density, but the overall feeding rate was negatively correlated. Naturally reared fry were dominant more often at low densities, and hatchery-reared fry were dominant more often at high densities. There were no significant effects of hatchery rearing treatment on aggression, feeding, dominance, or territory size. The only significant effect of rearing treatment was on the position of naturally reared fry, which occupied more upstream positions when stocked with conventional than with enriched hatchery-reared fry. Overall, rearing environment had relatively little influence on the behavior of steelhead fry. Our results indicate that stocking hatchery-reared steelhead fry at low densities may have effects on similar-size wild fish comparable to an equivalent increase in the density of wild fish. We suggest that releasing hatchery-reared steelhead fry as a supplementation strategy may have few direct negative ecological effects on wild fry.

[Assessment of ecological environment effects of coastal development in Hebei Province, China].

PubMed

Cui, Li-Tuo; Li, Zhi-Wei

2014-07-01

Through the analysis of the development activities and the ecological environment in coastal of Hebei Province, China, an index system for evaluating the ecological environment effect, composed of 28 indices, was set up by the pressure, state and response subsystems. Using the comprehensive index evaluation method, the integrated effects of ecological environment index (EI) was calculated and its grading criterion was founded. The results showed that the ecological environment effect of Hebei Province coastal development varied from being relatively small, normal and then relatively large from 1984 to 2010, and its acceptance degree evolved from being acceptable to being unacceptable. Because the resource and environment pressures caused by coastal development were serious and a delay existed in the state relative to the response, the improvement of various measures in the response subsystem did not show a positive effect on the state, and the environmental quality of ocean showed a degrading trend. Due to the differences in coastal development pattern and strength, the ecological environment effect of development activities showed some spatial differences. The ecological environment effect of Qinhuangdao coastal development was the minimum, followed by Cangzhou and Tangshan. Cangzhou and Tangshan had reached unacceptable levels and needed to further strengthen the restoration and protection of ecological environment.

NASA's Space Environments and Effects Program: Technology for the New Millennium

NASA Technical Reports Server (NTRS)

Hardage, Donna M.; Pearson, Steven D.

2000-01-01

Current trends in spacecraft development include the use of advanced technologies while maintaining the "faster, better, cheaper" philosophy. Spacecraft designers are continually designing with smaller and faster electronics as well as lighter and thinner materials providing better performance, lower weight, and ultimately lower costs. Given this technology trend, spacecraft will become increasingly susceptible to the harsh space environments, causing damaging or even disabling effects on space systems. NASA's Space Environments and Effects (SEE) Program defines the space environments and provides advanced technology development to support the design, development, and operation of spacecraft systems that will accommodate or mitigate effects due to the harsh space environments. This Program provides a comprehensive and focused approach to understanding the space environment, to define the best techniques for both flight and ground-based experimentation, to update the models which predict both the environments and the environmental effects on spacecraft, and finally to ensure that this multitudinous information is properly maintained and inserted into spacecraft design programs. A description of the SEE Program, its accomplishments, and future activities is provided.

40 CFR 262.103 - What is the scope of the laboratory environmental management standard?

Code of Federal Regulations, 2010 CFR

2010-07-01

... University Laboratories XL Project-Laboratory Environmental Management Standard § 262.103 What is the scope of the laboratory environmental management standard? The Laboratory Environmental Management Standard... environmental management standard? 262.103 Section 262.103 Protection of Environment ENVIRONMENTAL PROTECTION...

Environmental Effects of Hydrokinetic Turbines on Fish: Desktop and Laboratory Flume Studies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jacobson, Paul T.; Amaral, Stephen V.; Castro-Santos, Theodore

(greater than 90%) for fish less than 200 mm in length. Strike mortality was not predicted to occur during passage through a Welka UPG turbine at ambient current velocities less than about 2.5 m/s. Survival and Behavior of Juvenile Atlantic Salmon and Adult American Shad on Exposure to a Hydrokinetic Turbine This report describes a series of experiments designed to measure the effect of exposure to a full-scale, vertical axis hydrokinetic turbine on downstream migrating juvenile Atlantic salmon and upstream migrating adult American shad. Studies were performed in a large-scale, open-channel flume, and all individuals approached the turbine under volitional control. No injuries were observed, and there was no measurable increase in mortality associated with turbine passage. Exposure to the turbine elicited behavioral responses from both species, however, with salmon passing primarily over the downrunning blades. Shad movement was impeded in the presence of the device, as indicated by fewer attempts of shorter duration and reduced distance of ascent up the flume. More work should be performed in both laboratory and field conditions to determine the extent to which observed effects are likely to influence fish in riverine environments. Analysis is needed to assess the potential for multiple units to lead to greater mortality rates or impacts on fish movements and migrations. Additionally, future research should focus on expanding the existing data by developing better estimates of encounter and avoidance probabilities.« less

A Remote PLC Laboratory (RLab) for Distance Practical Work of Industrial Automation

NASA Astrophysics Data System (ADS)

Haritman, E.; Somantri, Y.; Wahyudin, D.; Mulyana, E.

2018-02-01

A laboratory is an essential equipment for engineering students to do a useful practical work. Therefore, universities should provide an adequate facility for practical work. On the other hand, industrial automation laboratory would offer students beneficial experience by using various educational PLC kits. This paper describes the development of Web-based Programmable Logic Controller (PLC) remote laboratory called RLab. It provides an environment for learners to study PLC application to control the level of the non-interacting tank. The RLab architecture is based on a Moodle and Remote Desktop, which also manages the booking system of the schedule of practical work in the laboratory. The RLab equipped by USB cameras providing a real-time view of PLC environment. To provide a secured system, the RLab combines Moodle and Remote Desktop application for the authentication system and management of remote users. Moodle will send PartnerID and password to connect to TeamViewer. It has been examined that the laboratory requirement, time and flexibility restrictions constitute a significant obstacle facing traditional students desiring to finish the course. A remote access laboratory can be eliminating time and flexibility restrictions. The preliminary study of RLab usability proved that such system is adequate to give the learners a distance practical work environment.

Space Environments and Effects Concept: Transitioning Research to Operations and Applications

NASA Technical Reports Server (NTRS)

Edwards, David L.; Spann, James; Burns, Howard D.; Schumacher, Dan

2012-01-01

The National Aeronautics and Space Administration (NASA) is embarking on a course to expand human presence beyond Low Earth Orbit (LEO) while expanding its mission to explore the solar system. Destinations such as Near Earth Asteroids (NEA), Mars and its moons, and the outer planets are but a few of the mission targets. NASA has established numerous offices specializing in specific space environments disciplines that will serve to enable these missions. To complement these existing discipline offices, a concept focusing on the development of space environment and effects application is presented. This includes space climate, space weather, and natural and induced space environments. This space environment and effects application is composed of 4 topic areas; characterization and modeling, engineering effects, prediction and operation, and mitigation and avoidance. These topic areas are briefly described below. Characterization and modeling of space environments will primarily focus on utilization during Program mission concept, planning, and design phases. Engineering effects includes materials testing and flight experiments producing data to be used in mission planning and design phases. Prediction and operation pulls data from existing sources into decision-making tools and empirical data sets to be used during the operational phase of a mission. Mitigation and avoidance will develop techniques and strategies used in the design and operations phases of the mission. The goal of this space environment and effects application is to develop decision-making tools and engineering products to support the mission phases of mission concept through operations by focusing on transitioning research to operations. Products generated by this space environments and effects application are suitable for use in anomaly investigations. This paper will outline the four topic areas, describe the need, and discuss an organizational structure for this space environments and effects

Microplastics in the aquatic and terrestrial environment: sources (with a specific focus on personal care products), fate and effects.

PubMed

Duis, Karen; Coors, Anja

2016-01-01

Due to the widespread use and durability of synthetic polymers, plastic debris occurs in the environment worldwide. In the present work, information on sources and fate of microplastic particles in the aquatic and terrestrial environment, and on their uptake and effects, mainly in aquatic organisms, is reviewed. Microplastics in the environment originate from a variety of sources. Quantitative information on the relevance of these sources is generally lacking, but first estimates indicate that abrasion and fragmentation of larger plastic items and materials containing synthetic polymers are likely to be most relevant. Microplastics are ingested and, mostly, excreted rapidly by numerous aquatic organisms. So far, there is no clear evidence of bioaccumulation or biomagnification. In laboratory studies, the ingestion of large amounts of microplastics mainly led to a lower food uptake and, consequently, reduced energy reserves and effects on other physiological functions. Based on the evaluated data, the lowest microplastic concentrations affecting marine organisms exposed via water are much higher than levels measured in marine water. In lugworms exposed via sediment, effects were observed at microplastic levels that were higher than those in subtidal sediments but in the same range as maximum levels in beach sediments. Hydrophobic contaminants are enriched on microplastics, but the available experimental results and modelling approaches indicate that the transfer of sorbed pollutants by microplastics is not likely to contribute significantly to bioaccumulation of these pollutants. Prior to being able to comprehensively assess possible environmental risks caused by microplastics a number of knowledge gaps need to be filled. However, in view of the persistence of microplastics in the environment, the high concentrations measured at some environmental sites and the prospective of strongly increasing concentrations, the release of plastics into the environment should be

The WEBSIM FISHBANKS Simulation Laboratory: Analysis of Its Ripple Effects

ERIC Educational Resources Information Center

Arantes do Amaral, João Alberto; Hess, Aurélio

2018-01-01

In this article, we discuss the ripple effects of the WEBSIM FISHBANKS Simulation Laboratory held at Federal University of Sao Paulo (UNIFESP) in 2014, held as a result of a partnership between the Sloan School of Management of the Massachusetts Institute of Technology, the UNIFESP, and the Brazilian Chapter of the System Dynamics Society of…

Planning for Shops and Laboratories.

ERIC Educational Resources Information Center

North Carolina State Dept. of Public Instruction, Raleigh. Div. of School Planning.

General guidelines for educators and architects in planning for industrial education, shops, and laboratory facilities necessary to the instructional program, are provided. Characteristics of the environment discussed are as follows--(1) spatial, (2) thermal, (3) visual, (4) sonic, and (5) aesthetic. Utility services covered are electrical power,…

The Pond Is Our Laboratory

ERIC Educational Resources Information Center

Marchewka, Barbara Turco

1978-01-01

This science teacher's laboratory is a pond within walking distance of his school that provides a stimulating environment for exploring the natural world. With simple materials students practice making careful observations, taking measurements and compiling and graphing information for their science studies. They also extend their pond experiences…

40 CFR 262.105 - What must be included in the laboratory environmental management plan?

Code of Federal Regulations, 2010 CFR

2010-07-01

... University Laboratories XL Project-Laboratory Environmental Management Standard § 262.105 What must be included in the laboratory environmental management plan? (a) Each University must include specific... laboratory environmental management plan? 262.105 Section 262.105 Protection of Environment ENVIRONMENTAL...

The effects of calculator-based laboratories on standardized test scores

NASA Astrophysics Data System (ADS)

Stevens, Charlotte Bethany Rains

Nationwide, the goal of providing a productive science and math education to our youth in today's educational institutions is centering itself around the technology being utilized in these classrooms. In this age of digital technology, educational software and calculator-based laboratories (CBL) have become significant devices in the teaching of science and math for many states across the United States. Among the technology, the Texas Instruments graphing calculator and Vernier Labpro interface, are among some of the calculator-based laboratories becoming increasingly popular among middle and high school science and math teachers in many school districts across this country. In Tennessee, however, it is reported that this type of technology is not regularly utilized at the student level in most high school science classrooms, especially in the area of Physical Science (Vernier, 2006). This research explored the effect of calculator based laboratory instruction on standardized test scores. The purpose of this study was to determine the effect of traditional teaching methods versus graphing calculator teaching methods on the state mandated End-of-Course (EOC) Physical Science exam based on ability, gender, and ethnicity. The sample included 187 total tenth and eleventh grade physical science students, 101 of which belonged to a control group and 87 of which belonged to the experimental group. Physical Science End-of-Course scores obtained from the Tennessee Department of Education during the spring of 2005 and the spring of 2006 were used to examine the hypotheses. The findings of this research study suggested the type of teaching method, traditional or calculator based, did not have an effect on standardized test scores. However, the students' ability level, as demonstrated on the End-of-Course test, had a significant effect on End-of-Course test scores. This study focused on a limited population of high school physical science students in the middle Tennessee

Unipedal balance in healthy adults: effect of visual environments yielding decreased lateral velocity feedback.

PubMed

Deyer, T W; Ashton-Miller, J A

1999-09-01

To test the (null) hypotheses that the reliability of unipedal balance is unaffected by the attenuation of visual velocity feedback and that, relative to baseline performance, deterioration of balance success rates from attenuated visual velocity feedback will not differ between groups of young men and older women, and the presence (or absence) of a vertical foreground object will not affect balance success rates. Single blind, single case study. University research laboratory. Two volunteer samples: 26 healthy young men (mean age, 20.0yrs; SD, 1.6); 23 healthy older women (mean age, 64.9 yrs; SD, 7.8). Normalized success rates in unipedal balance task. Subjects were asked to transfer to and maintain unipedal stance for 5 seconds in a task near the limit of their balance capabilities. Subjects completed 64 trials: 54 trials of three experimental visual scenes in blocked randomized sequences of 18 trials and 10 trials in a normal visual environment. The experimental scenes included two that provided strong velocity/weak position feedback, one of which had a vertical foreground object (SVWP+) and one without (SVWP-), and one scene providing weak velocity/strong position (WVSP) feedback. Subjects' success rates in the experimental environments were normalized by the success rate in the normal environment in order to allow comparisons between subjects using a mixed model repeated measures analysis of variance. The normalized success rate was significantly greater in SVWP+ than in WVSP (p = .0001) and SVWP- (p = .013). Visual feedback significantly affected the normalized unipedal balance success rates (p = .001); neither the group effect nor the group X visual environment interaction was significant (p = .9362 and p = .5634, respectively). Normalized success rates did not differ significantly between the young men and older women in any visual environment. Near the limit of the young men's or older women's balance capability, the reliability of transfer to unipedal

Implementation of a mentored professional development programme in laboratory leadership and management in the Middle East and North Africa.

PubMed

Perrone, L A; Confer, D; Scott, E; Livingston, L; Bradburn, C; McGee, A; Furtwangler, T; Downer, A; Mokdad, A H; Flandin, J F; Shotorbani, S; Asghar, H; Tolbah, H E; Ahmed, H J; Alwan, A; Martin, R

2017-02-01

Laboratories need leaders who can effectively utilize the laboratories' resources, maximize the laboratories'capacity to detect disease, and advocate for laboratories in a fluctuating health care environment. To address this need, the University of Washington, USA, created the Certificate Program in Laboratory Leadership and Management in partnership with WHO Regional Office for the Eastern Mediterranean, and implemented it with 17 participants and 11 mentors from clinical and public health laboratories in 10 countries (Egypt, Iraq, Jordan, Lebanon, Morocco, Oman, Pakistan, Qatar, Saudi Arabia, and Yemen) in 2014. Designed to teach leadership and management skills to laboratory supervisors, the programme enabled participants to improve laboratory testing quality and operations. The programme was successful overall, with 80% of participants completing it and making impactful changes in their laboratories. This success is encouraging and could serve as a model to further strengthen laboratory capacity in the Region.

An Overview of the Space Environments and Spacecraft Effects Organization Concept

NASA Technical Reports Server (NTRS)

Edwards, David L.; Burns, Howard D.; Garrett, Henry B.; Miller, Sharon K.; Peddie, Darilyn; Porter Ron; Spann, James F.; Xapsos, Michael A.

2012-01-01

The National Aeronautics and Space Administration (NASA) is embarking on a course to expand human presence beyond Low Earth Orbit (LEO) while also expanding its mission to explore our Earth, and the solar system. Destinations such as Near Earth Asteroids (NEA), Mars and its moons, and the outer planets are but a few of the mission targets. Each new destination presents an opportunity to increase our knowledge on the solar system and the unique environments for each mission target. NASA has multiple technical and science discipline areas specializing in specific space environments fields that will serve to enable these missions. To complement these existing discipline areas, a concept is presented focusing on the development of a space environment and spacecraft effects (SESE) organization. This SESE organization includes disciplines such as space climate, space weather, natural and induced space environments, effects on spacecraft materials and systems, and the transition of research information into application. This space environment and spacecraft effects organization will be composed of Technical Working Groups (TWG). These technical working groups will survey customers and users, generate products, and provide knowledge supporting four functional areas: design environments, engineering effects, operational support, and programmatic support. The four functional areas align with phases in the program mission lifecycle and are briefly described below. Design environments are used primarily in the mission concept and design phases of a program. Environment effects focuses on the material, component, sub-system, and system-level response to the space environment and include the selection and testing to verify design and operational performance. Operational support provides products based on real time or near real time space weather to mission operators to aid in real time and near-term decision-making. The programmatic support function maintains an interface with

Physiological responses to simulated firefighter exercise protocols in varying environments.

PubMed

Horn, Gavin P; Kesler, Richard M; Motl, Robert W; Hsiao-Wecksler, Elizabeth T; Klaren, Rachel E; Ensari, Ipek; Petrucci, Matthew N; Fernhall, Bo; Rosengren, Karl S

2015-01-01

For decades, research to quantify the effects of firefighting activities and personal protective equipment on physiology and biomechanics has been conducted in a variety of testing environments. It is unknown if these different environments provide similar information and comparable responses. A novel Firefighting Activities Station, which simulates four common fireground tasks, is presented for use with an environmental chamber in a controlled laboratory setting. Nineteen firefighters completed three different exercise protocols following common research practices. Simulated firefighting activities conducted in an environmental chamber or live-fire structures elicited similar physiological responses (max heart rate: 190.1 vs 188.0 bpm, core temperature response: 0.047°C/min vs 0.043°C/min) and accelerometry counts. However, the response to a treadmill protocol commonly used in laboratory settings resulted in significantly lower heart rate (178.4 vs 188.0 bpm), core temperature response (0.037°C/min vs 0.043°C/min) and physical activity counts compared with firefighting activities in the burn building. Practitioner Summary: We introduce a new approach for simulating realistic firefighting activities in a controlled laboratory environment for ergonomics assessment of fire service equipment and personnel. Physiological responses to this proposed protocol more closely replicate those from live-fire activities than a traditional treadmill protocol and are simple to replicate and standardise.

Burner Rig Laboratory

NASA Image and Video Library

2015-05-12

The Fuel Burner Rig is a test laboratory at NASA Glenn, which subjects new jet engine materials, treated with protective coatings, to the hostile, high temperature, high velocity environment found inside aircraft turbine engines. These samples face 200-mile per hour flames to simulate the temperatures of aircraft engines in flight. The rig can also simulate aircraft carrier and dusty desert operations where salt and sand can greatly reduce engine life and performance.

Aerosol-cloud feedbacks in a turbulent environment: Laboratory measurements representative of conditions in boundary layer clouds

NASA Astrophysics Data System (ADS)

Cantrell, W. H.; Chandrakar, K. K.; Karki, S.; Kinney, G.; Shaw, R.

2017-12-01

�mkohler number, the ratio of the characteristic turbulence timescale to the cloud's microphysical response time. Chang, K., et al., 2016. A laboratory facility to study gas-aerosol-cloud interactions in a turbulent environment: The Π Chamber. Bull. Amer. Meteor. Soc., doi:10.1175/BAMS-D-15-00203.1

Effects of laboratory housing on exploratory behaviour, novelty discrimination and spatial reference memory in a subterranean, solitary rodent, the Cape mole-rat (Georychus capensis).

PubMed

Oosthuizen, Maria Kathleen; Scheibler, Anne-Gita; Bennett, Nigel Charles; Amrein, Irmgard

2013-01-01

A large number of laboratory and field based studies are being carried out on mole-rats, both in our research group and others. Several studies have highlighted the development of adverse behaviours in laboratory animals and have emphasised the importance of enrichment for captive animals. Hence we were interested in evaluating how laboratory housing would affect behavioural performance in mole-rats. We investigated exploratory behaviour, the ability to discriminate between novel and familiar environments and reference memory in the solitary Cape mole-rat (Georychus capensis). Our data showed that both wild and captive animals readily explore open spaces and tunnels. Wild animals were however more active than their captive counterparts. In the Y maze two trial discrimination task, wild animals failed to discriminate between novel and familiar environments, while laboratory housed mole-rats showed preferential spatial discrimination in terms of the length of time spent in the novel arm. The performance of the laboratory and wild animals were similar when tested for reference memory in the Y maze, both groups showed a significant improvement compared to the first day, from the 3rd day onwards. Wild animals made more mistakes whereas laboratory animals were slower in completing the task. The difference in performance between wild and laboratory animals in the Y-maze may be as a result of the lower activity of the laboratory animals. Laboratory maintained Cape mole-rats show classic behaviours resulting from a lack of stimulation such as reduced activity and increased aggression. However, they do display an improved novelty discrimination compared to the wild animals. Slower locomotion rate of the laboratory animals may increase the integration time of stimuli, hence result in a more thorough inspection of the surroundings. Unlike the captive animals, wild animals show flexibility in their responses to unpredictable events, which is an important requirement under

Effects of Laboratory Housing on Exploratory Behaviour, Novelty Discrimination and Spatial Reference Memory in a Subterranean, Solitary Rodent, the Cape Mole-Rat (Georychus capensis)

PubMed Central

Oosthuizen, Maria Kathleen; Scheibler, Anne-Gita; Charles Bennett, Nigel; Amrein, Irmgard

2013-01-01

A large number of laboratory and field based studies are being carried out on mole-rats, both in our research group and others. Several studies have highlighted the development of adverse behaviours in laboratory animals and have emphasised the importance of enrichment for captive animals. Hence we were interested in evaluating how laboratory housing would affect behavioural performance in mole-rats. We investigated exploratory behaviour, the ability to discriminate between novel and familiar environments and reference memory in the solitary Cape mole-rat ( Georychus capensis ). Our data showed that both wild and captive animals readily explore open spaces and tunnels. Wild animals were however more active than their captive counterparts. In the Y maze two trial discrimination task, wild animals failed to discriminate between novel and familiar environments, while laboratory housed mole-rats showed preferential spatial discrimination in terms of the length of time spent in the novel arm. The performance of the laboratory and wild animals were similar when tested for reference memory in the Y maze, both groups showed a significant improvement compared to the first day, from the 3rd day onwards. Wild animals made more mistakes whereas laboratory animals were slower in completing the task. The difference in performance between wild and laboratory animals in the Y-maze may be as a result of the lower activity of the laboratory animals. Laboratory maintained Cape mole-rats show classic behaviours resulting from a lack of stimulation such as reduced activity and increased aggression. However, they do display an improved novelty discrimination compared to the wild animals. Slower locomotion rate of the laboratory animals may increase the integration time of stimuli, hence result in a more thorough inspection of the surroundings. Unlike the captive animals, wild animals show flexibility in their responses to unpredictable events, which is an important requirement under

The psychological effects of the physical healthcare environment on healthcare personnel.

PubMed

Tanja-Dijkstra, Karin; Pieterse, Marcel E

2011-01-19

The physical healthcare environment is capable of affecting patients. This concept of 'healing environments' refers to the psychological impact of environmental stimuli through sensory perceptions. It excludes more physiological effects such as those produced by ergonomic (i.e. fall prevention) or facilitative (i.e. hygiene-related) variables. The importance of an atmosphere in the healthcare environment that promotes the health and well-being of patients is evident, but this environment should not negatively affect healthcare personnel. The physical healthcare environment is part of the personnel's 'workscape'. This can make the environment an important determinant of subjective work-related outcomes like job satisfaction and well-being, as well as of objective outcomes like absenteeism or quality of care. In order to effectively build or renovate healthcare facilities, it is necessary to pay attention to the needs of both patients and healthcare personnel. To assess the psychological effects of the physical healthcare environment on healthcare personnel. We searched the Cochrane EPOC Group Specialised Register; Cochrane Central Register of Controlled Trials; Database of Abstracts and Reviews of Effects; MEDLINE; EMBASE; CINAHL; Civil Engineering Database and Compendex. We also searched the reference lists of included studies. We included randomised controlled trials (RCT), controlled clinical trials (CCT), controlled before and after studies (CBA), and interrupted time series (ITS) of psychological effects of the physical healthcare environment interventions for healthcare staff. The outcomes included measures of job satisfaction, satisfaction with the physical healthcare environment, quality of life, and quality of care. Two reviewers independently assessed studies for eligibility, extracted data, and assessed methodological quality. We identified one study, which adopted a CBA study design to investigate the simultaneous effects of multiple environmental

The Expectations of Teachers and Students Who Visit a Non-Formal Student Chemistry Laboratory

ERIC Educational Resources Information Center

Garner, Nicole; Eilks, Ingo

2015-01-01

Non-formal student laboratory environments for primary and secondary school science education have become a major trend in the German educational arena in recent years. These non-formal student laboratory environments are thought to offer unique experimental learning experiences that often cannot be realized in daily school routines. The biggest…

Laboratory Investigation of Astrophysical Collimated Jets with Intense Lasers

NASA Astrophysics Data System (ADS)

Yuan, Dawei; Li, Yutong; Tao, Tao; Wei, Huigang; Zhong, Jiayong; Zhu, Baojun; Li, Yanfei; Zhao, Jiarui; Li, Fang; Han, Bo; Zhang, Zhe; Liang, Guiyun; Wang, Feilu; Hu, Guangyue; Zheng, Jian; Jiang, Shaoen; Du, Kai; Ding, Yongkun; Zhou, Shenlei; Zhu, Baoqiang; Zhu, Jianqiang; Zhao, Gang; Zhang, Jie

2018-06-01

One of the remarkable dynamic features of the Herbig–Haro (HH) object is its highly collimated propagation far away from the accretion disk. Different factors are proposed to give us a clearly physical explanation behind these fascinating phenomena, including magnetic field, radiation cooling, surrounding medium, and so on. Laboratory astrophysics, as a new complementary method of studying astrophysical issues, can provide an insight into these behaviors in a similar and controllable laboratory environment. Here we report the scaled laboratory experiments that a well-collimated radiative jet with high Mach number is successfully created to mimic the evolution of HH objects. According to our results, we find that the radiation cooling effect within the jet and the outer rare surrounding plasmas from the X-ray (>keV) photoionized target contribute to the jet collimation. The local nonuniform density structures along the collimated radiative jet axis are caused by the pressure competition between the inner jet and the outer plasmas. The corresponding simulations performed with radiation-hydrodynamic codes FLASH reveal how the radiative jet evolves.

Laboratory-associated infections and biosafety.

PubMed Central

Sewell, D L

1995-01-01

An estimated 500,000 laboratory workers in the United States are at risk of exposure to infectious agents that cause disease ranging from inapparent to life-threatening infections, but the precise risk to a given worker unknown. The emergence of human immunodeficiency virus and hantavirus, the continuing problem of hepatitis B virus, and the reemergence of Mycobacterium tuberculosis have renewed interest in biosafety for the employees of laboratories and health care facilities. This review examines the history, the causes, and the methods for prevention of laboratory-associated infections. The initial step in a biosafety program is the assessment of risk to the employee. Risk assessment guidelines include the pathogenicity of the infectious agent, the method of transmission, worker-related risk factors, the source and route of infection, and the design of the laboratory facility. Strategies for the prevention and management of laboratory-associated infections are based on the containment of the infectious agent by physical separation from the laboratory worker and the environment, employee education about the occupational risks, and availability of an employee health program. Adherence to the biosafety guidelines mandated or proposed by various governmental and accrediting agencies reduces the risk of an occupational exposure to infectious agents handled in the workplace. PMID:7553572

Capillary-Effect Root-Environment System

NASA Technical Reports Server (NTRS)

Wright, Bruce D.

1991-01-01

Capillary-effect root-environment system (CERES) is experimental apparatus for growing plants in nutrient solutions. Solution circulated at slight tension in cavity filled with plastic screen and covered by porous plastic membrane. By adsorptive attraction, root draws solution through membrane. Conceived for use in microgravity of space, also finds terrestrial application in germinating seedlings, because it protects them from extremes of temperature, moisture, and soil pH and from overexposure to fertilizers and herbicides.

Environments for Fostering Effective Critical Thinking in Geotechnical Engineering Education (Geo-EFFECTs)

ERIC Educational Resources Information Center

Pierce, Charles E.; Gassman, Sarah L.; Huffman, Jeffrey T.

2013-01-01

This paper describes the development, implementation, and assessment of instructional materials for geotechnical engineering concepts using the Environments for Fostering Effective Critical Thinking (EFFECTs) pedagogical framework. The central learning goals of engineering EFFECTs are to (i) improve the understanding and retention of a specific…

Using Model Organisms in an Undergraduate Laboratory to Link Genotype, Phenotype, and the Environment

ERIC Educational Resources Information Center

Jacobs-McDaniels, Nicole L.; Maine, Eleanor M.; Albertson, R. Craig; Wiles, Jason R.

2013-01-01

We developed laboratory exercises using zebrafish ("Danio rerio") and nematodes ("Caenorhabditis elegans") for a sophomore-level Integrative Biology Laboratory course. Students examined live wildtype zebrafish at different stages of development and noted shifts occurring in response to "fgf8a" deficiency. Students were introduced to development in…

Adaptation to Temporally Fluctuating Environments by the Evolution of Maternal Effects.

PubMed

Dey, Snigdhadip; Proulx, Stephen R; Teotónio, Henrique

2016-02-01

All organisms live in temporally fluctuating environments. Theory predicts that the evolution of deterministic maternal effects (i.e., anticipatory maternal effects or transgenerational phenotypic plasticity) underlies adaptation to environments that fluctuate in a predictably alternating fashion over maternal-offspring generations. In contrast, randomizing maternal effects (i.e., diversifying and conservative bet-hedging), are expected to evolve in response to unpredictably fluctuating environments. Although maternal effects are common, evidence for their adaptive significance is equivocal since they can easily evolve as a correlated response to maternal selection and may or may not increase the future fitness of offspring. Using the hermaphroditic nematode Caenorhabditis elegans, we here show that the experimental evolution of maternal glycogen provisioning underlies adaptation to a fluctuating normoxia-anoxia hatching environment by increasing embryo survival under anoxia. In strictly alternating environments, we found that hermaphrodites evolved the ability to increase embryo glycogen provisioning when they experienced normoxia and to decrease embryo glycogen provisioning when they experienced anoxia. At odds with existing theory, however, populations facing irregularly fluctuating normoxia-anoxia hatching environments failed to evolve randomizing maternal effects. Instead, adaptation in these populations may have occurred through the evolution of fitness effects that percolate over multiple generations, as they maintained considerably high expected growth rates during experimental evolution despite evolving reduced fecundity and reduced embryo survival under one or two generations of anoxia. We develop theoretical models that explain why adaptation to a wide range of patterns of environmental fluctuations hinges on the existence of deterministic maternal effects, and that such deterministic maternal effects are more likely to contribute to adaptation than

Adaptation to Temporally Fluctuating Environments by the Evolution of Maternal Effects

PubMed Central

Dey, Snigdhadip; Proulx, Stephen R.; Teotónio, Henrique

2016-01-01

All organisms live in temporally fluctuating environments. Theory predicts that the evolution of deterministic maternal effects (i.e., anticipatory maternal effects or transgenerational phenotypic plasticity) underlies adaptation to environments that fluctuate in a predictably alternating fashion over maternal-offspring generations. In contrast, randomizing maternal effects (i.e., diversifying and conservative bet-hedging), are expected to evolve in response to unpredictably fluctuating environments. Although maternal effects are common, evidence for their adaptive significance is equivocal since they can easily evolve as a correlated response to maternal selection and may or may not increase the future fitness of offspring. Using the hermaphroditic nematode Caenorhabditis elegans, we here show that the experimental evolution of maternal glycogen provisioning underlies adaptation to a fluctuating normoxia–anoxia hatching environment by increasing embryo survival under anoxia. In strictly alternating environments, we found that hermaphrodites evolved the ability to increase embryo glycogen provisioning when they experienced normoxia and to decrease embryo glycogen provisioning when they experienced anoxia. At odds with existing theory, however, populations facing irregularly fluctuating normoxia–anoxia hatching environments failed to evolve randomizing maternal effects. Instead, adaptation in these populations may have occurred through the evolution of fitness effects that percolate over multiple generations, as they maintained considerably high expected growth rates during experimental evolution despite evolving reduced fecundity and reduced embryo survival under one or two generations of anoxia. We develop theoretical models that explain why adaptation to a wide range of patterns of environmental fluctuations hinges on the existence of deterministic maternal effects, and that such deterministic maternal effects are more likely to contribute to adaptation than

The Entrance and Exit Effects in Small Electrochemical Filter-Press Reactors Used in the Laboratory

ERIC Educational Resources Information Center

Frias-Ferrer, Angel; Gonzalez-Garcia, Jose; Saez, Veronica; Exposito, Eduardo; Sanchez-Sanchez, Carlos M.; Mantiel, Vicente; Walsh, Frank C.; Aldaz, Antonio; Walsh, Frank C.

2005-01-01

A laboratory experiment designed to examine the entrance and exit effects in small electrochemical filter-press reactors used in the laboratory is presented. The single compartment of the filter-press reactor is filled with different turbulence promoters to study their influence as compared to the empty configuration.

EFFECTS OF SEDIMENT TYPE ON BENTHIC MACROINFAUNAL COLONIZATION OF LABORATORY MICROCOSMS

EPA Science Inventory

We tested the effects of four different sediment types on macroinfaunal colonization and community development in our laboratory flow-thru microcosm system (all microcosms were 20 cm side-1 and sediment depth was 5 cm) over a period of 41 days. Sediments included Santa Rosa Islan...

Space Environments and Spacecraft Effects Concept: Transitioning Research to Operations and Applications

NASA Technical Reports Server (NTRS)

Edwards, D. L.; Burns, H. D.; Clinton, R. G.; Schumacher, D.; Spann, J. F.

2012-01-01

The National Aeronautics and Space Administration (NASA) is embarking on a course to expand human presence beyond Low Earth Orbit (LEO) while expanding its mission to explore the solar system. Destinations such as Near Earth Asteroids (NEA), Mars and its moons, and the outer planets are but a few of the mission targets. NASA has established numerous organizations specializing in specific space environments disciplines that will serve to enable these missions. To complement these existing discipline organizations, a concept is presented focusing on the development of a space environment and spacecraft effects organization. This includes space climate, space weather, natural and induced space environments, and effects on spacecraft materials and systems. This space environment and spacecraft effects organization would be comprised of Technical Working Groups (TWG) focusing on, for example: a) Charged Particles (CP), b) Space Environmental Effects (SEE), and c) Interplanetary and Extraterrestrial Environments (IEE). These technical working groups will generate products and provide knowledge supporting four functional areas: design environments, environment effects, operational support, and programmatic support. The four functional areas align with phases in the program mission lifecycle and are briefly described below. Design environments are used primarily in the mission concept and design phases of a program. Environment effects focuses on the material, component, sub-system and system-level selection and the testing to verify design and operational performance. Operational support provides products based on real time or near real time space weather observations to mission operators to aid in real time and near-term decision-making. The programmatic support function maintains an interface with the numerous programs within NASA and other federal agencies to ensure that communications are well established and the needs of the programs are being met. The programmatic

No effect of a parasite on reproduction in stickleback males: a laboratory artefact?

PubMed

Candolin, U; Voigt, H R

2001-04-01

Experiments are often carried out in the laboratory under artificial conditions. Although this can control for confounding factors, it may eliminate important factors that under natural conditions mediate the interaction under investigation. Here, we show that different results can be gained in the field and in the laboratory regarding host-parasite interaction. In the field, courting three-spined stickleback males, Gasterosteus aculeatus, were less often infected with plerocercoids of a cestode tapeworm, Schistocephalus solidus, than shoaling males. However, when a random sample of males was allowed to nest and court females in individual aquaria in the laboratory, both uninfected and infected males built nests and courted females. Moreover, while the few infected males that courted females in the field expressed less red nuptial coloration than uninfected courting males, there was no difference in redness between infected and uninfected males in the laboratory. We argue that the different results gained in the field and in the laboratory are due to differences in the cost of reproduction, due to differences in the resource pool of the males. The favourable conditions in the laboratory exclude factors such as predation risk, social interactions, and fluctuating environmental conditions that may use up resources in the field and mediate the effect of the parasite.

Children's Storytelling: The Effect of Preschool and Family Environment

ERIC Educational Resources Information Center

Fekonja-Peklaj, Urska; Marjanovic-Umek, Ljubica; Kranjc, Simona

2010-01-01

Storytelling reflects children's pragmatic language ability, which develops rapidly in early childhood and is related to various characteristics of the child's environment. This study examines the effect of preschool, maternal education and quality of the home environment on children's storytelling skills. The sample included 229 Slovenian…

Web Geometry Laboratory: Case Studies in Portugal and Serbia

ERIC Educational Resources Information Center

Santos, Vanda; Quaresma, Pedro; Maric, Milena; Campos, Helena

2018-01-01

The role of information and communication technologies (ICT) in education is well recognised--learning environments where the ICT features included are being proposed for many years now. The Web Geometry Laboratory (WGL) innovates in proposing a blended learning, collaborative and adaptive learning Web-environment for geometry. It integrates a…

The Effects of Exercising in Different Natural Environments on Psycho-Physiological Outcomes in Post-Menopausal Women: A Simulation Study.

PubMed

White, Mathew P; Pahl, Sabine; Ashbullby, Katherine J; Burton, Francesca; Depledge, Michael H

2015-09-23

The current study examined potential psycho-physiological benefits from exercising in simulated natural environments among a sample of post-menopausal women using a laboratory based protocol. Participants cycled on a stationary exercise bike for 15 min while facing either a blank wall (Control) or while watching one of three videos: Urban (Grey), Countryside (Green), Coast (Blue). Blood pressure, heart rate and affective responses were measured pre-post. Heart rate, affect, perceived exertion and time perception were also measured at 5, 10 and 15 min during exercise. Experience evaluation was measured at the end. Replicating most earlier findings, affective, but not physiological, outcomes were more positive for exercise in the simulated Green and, for the first time, Blue environment, compared to Control. Moreover, only the simulated Blue environment was associated with shorter perceived exercise duration than Control and participants were most willing to repeat exercise in the Blue setting. The current research extended earlier work by exploring the effects of "blue exercise" and by using a demographic with relatively low average levels of physical activity. That this sample of postmenopausal women were most willing to repeat a bout of exercise in a simulated Blue environment may be important for physical activity promotion in this cohort.

The Effects of Exercising in Different Natural Environments on Psycho-Physiological Outcomes in Post-Menopausal Women: A Simulation Study

PubMed Central

White, Mathew P.; Pahl, Sabine; Ashbullby, Katherine J.; Burton, Francesca; Depledge, Michael H.

2015-01-01

The current study examined potential psycho-physiological benefits from exercising in simulated natural environments among a sample of post-menopausal women using a laboratory based protocol. Participants cycled on a stationary exercise bike for 15 min while facing either a blank wall (Control) or while watching one of three videos: Urban (Grey), Countryside (Green), Coast (Blue). Blood pressure, heart rate and affective responses were measured pre-post. Heart rate, affect, perceived exertion and time perception were also measured at 5, 10 and 15 min during exercise. Experience evaluation was measured at the end. Replicating most earlier findings, affective, but not physiological, outcomes were more positive for exercise in the simulated Green and, for the first time, Blue environment, compared to Control. Moreover, only the simulated Blue environment was associated with shorter perceived exercise duration than Control and participants were most willing to repeat exercise in the Blue setting. The current research extended earlier work by exploring the effects of “blue exercise” and by using a demographic with relatively low average levels of physical activity. That this sample of postmenopausal women were most willing to repeat a bout of exercise in a simulated Blue environment may be important for physical activity promotion in this cohort. PMID:26404351

Raising Virtual Laboratories in Australia onto global platforms

NASA Astrophysics Data System (ADS)

Wyborn, L. A.; Barker, M.; Fraser, R.; Evans, B. J. K.; Moloney, G.; Proctor, R.; Moise, A. F.; Hamish, H.

2016-12-01

Across the globe, Virtual Laboratories (VLs), Science Gateways (SGs), and Virtual Research Environments (VREs) are being developed that enable users who are not co-located to actively work together at various scales to share data, models, tools, software, workflows, best practices, etc. Outcomes range from enabling `long tail' researchers to more easily access specific data collections, to facilitating complex workflows on powerful supercomputers. In Australia, government funding has facilitated the development of a range of VLs through the National eResearch Collaborative Tools and Resources (NeCTAR) program. The VLs provide highly collaborative, research-domain oriented, integrated software infrastructures that meet user community needs. Twelve VLs have been funded since 2012, including the Virtual Geophysics Laboratory (VGL); Virtual Hazards, Impact and Risk Laboratory (VHIRL); Climate and Weather Science Laboratory (CWSLab); Marine Virtual Laboratory (MarVL); and Biodiversity and Climate Change Virtual Laboratory (BCCVL). These VLs share similar technical challenges, with common issues emerging on integration of tools, applications and access data collections via both cloud-based environments and other distributed resources. While each VL began with a focus on a specific research domain, communities of practice have now formed across the VLs around common issues, and facilitate identification of best practice case studies, and new standards. As a result, tools are now being shared where the VLs access data via data services using international standards such as ISO, OGC, W3C. The sharing of these approaches is starting to facilitate re-usability of infrastructure and is a step towards supporting interdisciplinary research. Whilst the focus of the VLs are Australia-centric, by using standards, these environments are able to be extended to analysis on other international datasets. Many VL datasets are subsets of global datasets and so extension to global is a

Effects of work environment on patient and nurse outcomes.

PubMed

Copanitsanou, Panagiota; Fotos, Nikolaos; Brokalaki, Hero

2017-02-09

Several parameters of the nurse's work environment lead to fewer patient complications and lower nurse burnout. The aim of this systematic review was the analysis of research data related to the effect of nurses' work environments on outcomes for both patients and nurses. Medline was searched by using keywords: 'working conditions', 'work environment', 'nurses', 'nursing staff', 'patients', 'outcomes'. In total, 10 studies were included, of which 4 were cross-sectional and the remaining were descriptive correlational studies. Patients who were hospitalised in units with good work environments for the nurses were more satisfied with the nursing care than the patients in units with poor work environments. Nurses who perceived their work environment to be good experienced higher job satisfaction and lower rates of burnout syndrome. A good work environment constitutes a determinant factor for high care quality and, at the same time, relates to improved outcomes for the nurses.

The effect of introducing computers into an introductory physics problem-solving laboratory

NASA Astrophysics Data System (ADS)

McCullough, Laura Ellen

2000-10-01

Computers are appearing in every type of classroom across the country. Yet they often appear without benefit of studying their effects. The research that is available on computer use in classrooms has found mixed results, and often ignores the theoretical and instructional contexts of the computer in the classroom. The University of Minnesota's physics department employs a cooperative-group problem solving pedagogy, based on a cognitive apprenticeship instructional model, in its calculus-based introductory physics course. This study was designed to determine possible negative effects of introducing a computerized data-acquisition and analysis tool into this pedagogy as a problem-solving tool for students to use in laboratory. To determine the effects of the computer tool, two quasi-experimental treatment groups were selected. The computer-tool group (N = 170) used a tool, designed for this study (VideoTool), to collect and analyze motion data in the laboratory. The control group (N = 170) used traditional non-computer equipment (spark tapes and Polaroid(TM) film). The curriculum was kept as similar as possible for the two groups. During the ten week academic quarter, groups were examined for effects on performance on conceptual tests and grades, attitudes towards the laboratory and the laboratory tools, and behaviors within cooperative groups. Possible interactions with gender were also examined. Few differences were found between the control and computer-tool groups. The control group received slightly higher scores on one conceptual test, but this difference was not educationally significant. The computer-tool group had slightly more positive attitudes towards using the computer tool than their counterparts had towards the traditional tools. The computer-tool group also perceived that they spoke more frequently about physics misunderstandings, while the control group felt that they discussed equipment difficulties more often. This perceptual difference interacted

Full-participation of students with physical disabilities in science and engineering laboratories.

PubMed

Jeannis, Hervens; Joseph, James; Goldberg, Mary; Seelman, Katherine; Schmeler, Mark; Cooper, Rory A

2018-02-01

To conduct a literature review identifying barriers and facilitators students with physical disabilities (SwD-P) may encounter in science and engineering (S&E) laboratories. Publications were identified from 1991 to 2015 in ERIC, web of science via web of knowledge, CINAHL, SCOPUS, IEEEXplore, engineering village, business source complete and PubMed databases using search terms and synonyms for accommodations, advanced manufacturing, additive manufacturing, assistive technology (AT), barriers, engineering, facilitators, instructor, laboratory, STEM education, science, students with disabilities and technology. Twenty-two of the 233 publications that met the review's inclusion criteria were examined. Barriers and facilitators were grouped based on the international classification of functioning, disability and health framework (ICF). None of the studies directly found barriers or facilitators to SwD-P in science or engineering laboratories within postsecondary environments. The literature is not clear on the issues specifically related to SwD-P. Given these findings, further research (e.g., surveys or interviews) should be conducted to identify more details to obtain more substantial information on the barriers that may prevent SwD-P from fully participating in S&E instructional laboratories. Implications for Rehabilitation Students with disabilities remain underrepresented going into STEM careers. A need exist to help uncover barriers students with disabilities encounter in STEM laboratory. Environments. Accommodations and strategies that facilitate participation in STEM laboratory environments are promising for students with disabilities.

Effect of Population Heterogenization on the Reproducibility of Mouse Behavior: A Multi-Laboratory Study

PubMed Central

Richter, S. Helene; Garner, Joseph P.; Zipser, Benjamin; Lewejohann, Lars; Sachser, Norbert; Touma, Chadi; Schindler, Britta; Chourbaji, Sabine; Brandwein, Christiane; Gass, Peter; van Stipdonk, Niek; van der Harst, Johanneke; Spruijt, Berry; Võikar, Vootele; Wolfer, David P.; Würbel, Hanno

2011-01-01

In animal experiments, animals, husbandry and test procedures are traditionally standardized to maximize test sensitivity and minimize animal use, assuming that this will also guarantee reproducibility. However, by reducing within-experiment variation, standardization may limit inference to the specific experimental conditions. Indeed, we have recently shown in mice that standardization may generate spurious results in behavioral tests, accounting for poor reproducibility, and that this can be avoided by population heterogenization through systematic variation of experimental conditions. Here, we examined whether a simple form of heterogenization effectively improves reproducibility of test results in a multi-laboratory situation. Each of six laboratories independently ordered 64 female mice of two inbred strains (C57BL/6NCrl, DBA/2NCrl) and examined them for strain differences in five commonly used behavioral tests under two different experimental designs. In the standardized design, experimental conditions were standardized as much as possible in each laboratory, while they were systematically varied with respect to the animals' test age and cage enrichment in the heterogenized design. Although heterogenization tended to improve reproducibility by increasing within-experiment variation relative to between-experiment variation, the effect was too weak to account for the large variation between laboratories. However, our findings confirm the potential of systematic heterogenization for improving reproducibility of animal experiments and highlight the need for effective and practicable heterogenization strategies. PMID:21305027

Psychophysiological measures of cognitive workload in laboratory and flight

NASA Technical Reports Server (NTRS)

Wilson, Glenn F.; Badeau, Albert

1993-01-01

Psychophysiological data have been recorded during different levels of cognitive workload in laboratory and flight settings. Cardiac, eye blink, and brain data have shown meaningful changes as a function of the levels of mental workload. Increased cognitive workload is generally associated with increased heart rates, decreased blink rates and eye closures, and decreased evoked potential amplitudes. However, comparisons of laboratory and flight data show that direct transference of laboratory findings to the flight environment is not possible in many cases. While the laboratory data are valuable, a data base from flight is required so that 'real world' data can be properly interpreted.

Assessing the welfare of laboratory mice in their home environment using animal-based measures--a benchmarking tool.

PubMed

Spangenberg, Elin M F; Keeling, Linda J

2016-02-01

Welfare problems in laboratory mice can be a consequence of an ongoing experiment, or a characteristic of a particular genetic line, but in some cases, such as breeding animals, they are most likely to be a result of the design and management of the home cage. Assessment of the home cage environment is commonly performed using resource-based measures, like access to nesting material. However, animal-based measures (related to the health status and behaviour of the animals) can be used to assess the current welfare of animals regardless of the inputs applied (i.e. the resources or management). The aim of this study was to design a protocol for assessing the welfare of laboratory mice using only animal-based measures. The protocol, to be used as a benchmarking tool, assesses mouse welfare in the home cage and does not contain parameters related to experimental situations. It is based on parameters corresponding to the 12 welfare criteria established by the Welfare Quality® project. Selection of animal-based measures was performed by scanning existing published, web-based and informal protocols, and by choosing parameters that matched these criteria, were feasible in practice and, if possible, were already validated indicators of mouse welfare. The parameters should identify possible animal welfare problems and enable assessment directly in an animal room during cage cleaning procedures, without the need for extra equipment. Thermal comfort behaviours and positive emotional states are areas where more research is needed to find valid, reliable and feasible animal-based measures. © The Author(s) 2015.

Laboratory Activities in Israel

ERIC Educational Resources Information Center

Mamlok-Naaman, Rachel; Barnea, Nitza

2012-01-01

Laboratory activities have long had a distinctive and central role in the science curriculum, and science educators have suggested that many benefits accrue from engaging students in science laboratory activities. Many research studies have been conducted to investigate the educational effectiveness of laboratory work in science education in…

An evaluation of community college student perceptions of the science laboratory and attitudes towards science in an introductory biology course

NASA Astrophysics Data System (ADS)

Robinson, Nakia Rae

The science laboratory is an integral component of science education. However, the academic value of student participation in the laboratory is not clearly understood. One way to discern student perceptions of the science laboratory is by exploring their views of the classroom environment. The classroom environment is one determinant that can directly influence student learning and affective outcomes. Therefore, this study sought to examine community college students' perceptions of the laboratory classroom environment and their attitudes toward science. Quantitative methods using two survey instruments, the Science Laboratory Environment Instrument (SLEI) and the Test of Science Related Attitudes (TORSA) were administered to measure laboratory perceptions and attitudes, respectively. A determination of differences among males and females as well as three academic streams were examined. Findings indicated that overall community college students had positive views of the laboratory environment regardless of gender of academic major. However, the results indicated that the opportunity to pursue open-ended activities in the laboratory was not prevalent. Additionally, females viewed the laboratory material environment more favorably than their male classmates did. Students' attitudes toward science ranged from favorable to undecided and no significant gender differences were present. However, there were significantly statistical differences between the attitudes of nonscience majors compared to both allied health and STEM majors. Nonscience majors had less positive attitudes toward scientific inquiry, adoption of scientific attitudes, and enjoyment of science lessons. Results also indicated that collectively, students' experiences in the laboratory were positive predicators of their attitudes toward science. However, no laboratory environment scale was a significant independent predictor of student attitudes. .A students' academic streams was the only significant

NRMRL SCIENCE PUBLICATIONS (NATIONAL RISK MANAGEMENT RESEARCH LABORATORY, EPA, CINCINNATI, OH)

EPA Science Inventory

The National Risk Management Research Laboratory (NRMRL)is the U.S.EPA's center for investigating technological and management approaches for preventing and reducing risks from pollution that threaten human health and the environment. The focus of the Laboratory's research progra...

NATIONAL RISK MANAGEMENT RESEARCH LABORATORY - PROVIDING SOLUTIONS FOR A BETTER TOMORROW

EPA Science Inventory

As part of the U.S. Environmental Protection Agency's Office of Research and Development, the National Risk Management Research Laboratory (NRMRL) conducts research into ways to prevent and reduce pollution risks that threaten human health and the environment. The laboratory inve...

An effective medium inversion algorithm for gas hydrate quantification and its application to laboratory and borehole measurements of gas hydrate-bearing sediments

NASA Astrophysics Data System (ADS)

Chand, Shyam; Minshull, Tim A.; Priest, Jeff A.; Best, Angus I.; Clayton, Christopher R. I.; Waite, William F.

2006-08-01

The presence of gas hydrate in marine sediments alters their physical properties. In some circumstances, gas hydrate may cement sediment grains together and dramatically increase the seismic P- and S-wave velocities of the composite medium. Hydrate may also form a load-bearing structure within the sediment microstructure, but with different seismic wave attenuation characteristics, changing the attenuation behaviour of the composite. Here we introduce an inversion algorithm based on effective medium modelling to infer hydrate saturations from velocity and attenuation measurements on hydrate-bearing sediments. The velocity increase is modelled as extra binding developed by gas hydrate that strengthens the sediment microstructure. The attenuation increase is modelled through a difference in fluid flow properties caused by different permeabilities in the sediment and hydrate microstructures. We relate velocity and attenuation increases in hydrate-bearing sediments to their hydrate content, using an effective medium inversion algorithm based on the self-consistent approximation (SCA), differential effective medium (DEM) theory, and Biot and squirt flow mechanisms of fluid flow. The inversion algorithm is able to convert observations in compressional and shear wave velocities and attenuations to hydrate saturation in the sediment pore space. We applied our algorithm to a data set from the Mallik 2L-38 well, Mackenzie delta, Canada, and to data from laboratory measurements on gas-rich and water-saturated sand samples. Predictions using our algorithm match the borehole data and water-saturated laboratory data if the proportion of hydrate contributing to the load-bearing structure increases with hydrate saturation. The predictions match the gas-rich laboratory data if that proportion decreases with hydrate saturation. We attribute this difference to differences in hydrate formation mechanisms between the two environments.

An effective medium inversion algorithm for gas hydrate quantification and its application to laboratory and borehole measurements of gas hydrate-bearing sediments

USGS Publications Warehouse

Chand, S.; Minshull, T.A.; Priest, J.A.; Best, A.I.; Clayton, C.R.I.; Waite, W.F.

2006-01-01

The presence of gas hydrate in marine sediments alters their physical properties. In some circumstances, gas hydrate may cement sediment grains together and dramatically increase the seismic P- and S-wave velocities of the composite medium. Hydrate may also form a load-bearing structure within the sediment microstructure, but with different seismic wave attenuation characteristics, changing the attenuation behaviour of the composite. Here we introduce an inversion algorithm based on effective medium modelling to infer hydrate saturations from velocity and attenuation measurements on hydrate-bearing sediments. The velocity increase is modelled as extra binding developed by gas hydrate that strengthens the sediment microstructure. The attenuation increase is modelled through a difference in fluid flow properties caused by different permeabilities in the sediment and hydrate microstructures. We relate velocity and attenuation increases in hydrate-bearing sediments to their hydrate content, using an effective medium inversion algorithm based on the self-consistent approximation (SCA), differential effective medium (DEM) theory, and Biot and squirt flow mechanisms of fluid flow. The inversion algorithm is able to convert observations in compressional and shear wave velocities and attenuations to hydrate saturation in the sediment pore space. We applied our algorithm to a data set from the Mallik 2L–38 well, Mackenzie delta, Canada, and to data from laboratory measurements on gas-rich and water-saturated sand samples. Predictions using our algorithm match the borehole data and water-saturated laboratory data if the proportion of hydrate contributing to the load-bearing structure increases with hydrate saturation. The predictions match the gas-rich laboratory data if that proportion decreases with hydrate saturation. We attribute this difference to differences in hydrate formation mechanisms between the two environments.

Medical Service Clinical Laboratory Procedures--Bacteriology.

ERIC Educational Resources Information Center

Department of the Army, Washington, DC.

This manual presents laboratory procedures for the differentiation and identification of disease agents from clinical materials. Included are procedures for the collection of specimens, preparation of culture media, pure culture methods, cultivation of the microorganisms in natural and simulated natural environments, and procedures in…

The Effect of High School Physics Laboratories on Performance in Introductory College Physics

NASA Astrophysics Data System (ADS)

Maltese, Adam V.; Tai, Robert H.; Sadler, Philip M.

2010-05-01

Laboratory experiences play a substantial role in most high school science courses, and many teachers believe the number of labs they offer is a measure of the quality of their curriculum. While some teachers believe labs are meant to confirm concepts taught during lectures, others feel labs should address students' everyday beliefs about the world. Still other teachers emphasize learning of the scientific method and laboratory techniques. Accordingly, many articles offer advice on "effective" pedagogical practices.2-5

Space Environment Effects: Model for Emission of Solar Protons (ESP): Cumulative and Worst Case Event Fluences

NASA Technical Reports Server (NTRS)

Xapsos, M. A.; Barth, J. L.; Stassinopoulos, E. G.; Burke, E. A.; Gee, G. B.

1999-01-01

The effects that solar proton events have on microelectronics and solar arrays are important considerations for spacecraft in geostationary and polar orbits and for interplanetary missions. Designers of spacecraft and mission planners are required to assess the performance of microelectronic systems under a variety of conditions. A number of useful approaches exist for predicting information about solar proton event fluences and, to a lesser extent, peak fluxes. This includes the cumulative fluence over the course of a mission, the fluence of a worst-case event during a mission, the frequency distribution of event fluences, and the frequency distribution of large peak fluxes. Naval Research Laboratory (NRL) and NASA Goddard Space Flight Center, under the sponsorship of NASA's Space Environments and Effects (SEE) Program, have developed a new model for predicting cumulative solar proton fluences and worst-case solar proton events as functions of mission duration and user confidence level. This model is called the Emission of Solar Protons (ESP) model.

Space Environment Effects: Model for Emission of Solar Protons (ESP)--Cumulative and Worst-Case Event Fluences

NASA Technical Reports Server (NTRS)

Xapsos, M. A.; Barth, J. L.; Stassinopoulos, E. G.; Burke, Edward A.; Gee, G. B.

1999-01-01

The effects that solar proton events have on microelectronics and solar arrays are important considerations for spacecraft in geostationary and polar orbits and for interplanetary missions. Designers of spacecraft and mission planners are required to assess the performance of microelectronic systems under a variety of conditions. A number of useful approaches exist for predicting information about solar proton event fluences and, to a lesser extent, peak fluxes. This includes the cumulative fluence over the course of a mission, the fluence of a worst-case event during a mission, the frequency distribution of event fluences, and the frequency distribution of large peak fluxes. Naval Research Laboratory (NRL) and NASA Goddard Space Flight Center, under the sponsorship of NASA's Space Environments and Effects (SEE) Program, have developed a new model for predicting cumulative solar proton fluences and worst-case solar proton events as functions of mission duration and user confidence level. This model is called the Emission of Solar Protons (ESP) model.

Integration Head Mounted Display Device and Hand Motion Gesture Device for Virtual Reality Laboratory

NASA Astrophysics Data System (ADS)

Rengganis, Y. A.; Safrodin, M.; Sukaridhoto, S.

2018-01-01

Virtual Reality Laboratory (VR Lab) is an innovation for conventional learning media which show us whole learning process in laboratory. There are many tools and materials are needed by user for doing practical in it, so user could feel new learning atmosphere by using this innovation. Nowadays, technologies more sophisticated than before. So it would carry in education and it will be more effective, efficient. The Supported technologies are needed us for making VR Lab such as head mounted display device and hand motion gesture device. The integration among them will be used us for making this research. Head mounted display device for viewing 3D environment of virtual reality laboratory. Hand motion gesture device for catching user real hand and it will be visualized in virtual reality laboratory. Virtual Reality will show us, if using the newest technologies in learning process it could make more interesting and easy to understand.

Cruise Stage Testing for Mars Science Laboratory

NASA Image and Video Library

2010-09-02

Testing of the cruise stage for NASA Mars Science Laboratory in August 2010 included a session in a facility that simulates the environment found in interplanetary space. Spacecraft technicians at JPL prepare a space-simulation test.

Laboratory Maintenance of Acinetobacter baumannii.

PubMed

Jacobs, Anna C; Zurawski, Daniel V

2014-11-03

Acinetobacter baumannii has recently drawn great interest in the microbiology research community due to the increase in clinical antibiotic resistance of this organism, and persistence of this bacterial species in the hospital environment. This unit outlines protocols for the growth and maintenance of A. baumannii in the laboratory. Copyright © 2014 John Wiley & Sons, Inc.

Idaho National Laboratory Integrated Safety Management System FY 2013 Effectiveness Review and Declaration Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hunt, Farren

2013-12-01

Idaho National Laboratory (INL) performed an Annual Effectiveness Review of the Integrated Safety Management System (ISMS), per 48 Code of Federal Regulations (CFR) 970.5223 1, “Integration of Environment, Safety and Health into Work Planning and Execution.” The annual review assessed Integrated Safety Management (ISM) effectiveness, provided feedback to maintain system integrity, and identified target areas for focused improvements and assessments for Fiscal Year (FY) 2014. Results of the FY 2013 annual effectiveness review demonstrate that the INL’s ISMS program is “Effective” and continually improving and shows signs of being significantly strengthened. Although there have been unacceptable serious events in themore » past, there has also been significant attention, dedication, and resources focused on improvement, lessons learned and future prevention. BEA’s strategy of focusing on these improvements includes extensive action and improvement plans that include PLN 4030, “INL Sustained Operational Improvement Plan, PLN 4058, “MFC Strategic Excellence Plan,” PLN 4141, “ATR Sustained Excellence Plan,” and PLN 4145, “Radiological Control Road to Excellence,” and the development of LWP 20000, “Conduct of Research.” As a result of these action plans, coupled with other assurance activities and metrics, significant improvement in operational performance, organizational competence, management oversight and a reduction in the number of operational events is being realized. In short, the realization of the fifth core function of ISMS (feedback and continuous improvement) and the associated benefits are apparent.« less

Relativistic jets: An astrophysical laboratory for the Doppler effect

NASA Astrophysics Data System (ADS)

Zakamska, Nadia L.

2018-05-01

Special Relativity is one of the most abstract courses in the standard curriculum for physics majors, and therefore practical applications or laboratory exercises are particularly valuable for providing real-world experiences with this subject. This course poses a challenge for lab development because relativistic effects manifest themselves only at speeds close to the speed of light. The laboratory described in this paper constitutes a low-cost, low-barrier exercise suitable for students whose only background is the standard mechanics-plus-electromagnetism sequence. The activity uses research-quality astronomical data on SS433—a fascinating Galactic X-ray binary consisting of a compact object (a neutron star or a black hole) and a normal star. A pair of moderately relativistic jets moving with v ˜ 0.3 c in opposite directions emanate from the vicinity of the compact object and are clearly detected in optical and radio observations. Following step-by-step instructions, students develop a full kinematic model of a complex real-world source, use the model to fit the observational data, obtain best-fit parameters, and understand the limitations of the model. The observations are in exquisite agreement with the Doppler effect equations of Special Relativity. The complete lab manual, the dataset and the solutions are available in online supplemental materials; this paper presents the scientific and pedagogical background for the exercise.

Effects of environment on microhardness of magnesium oxide

NASA Technical Reports Server (NTRS)

Ishigaki, H.; Buckley, D. H.

1982-01-01

Micro-Vickers hardness measurements of magnesium oxide single crystals were conducted in various environments. These environments included air, nitrogen gas, water, mineral oil with or without various additives, and aqueous solutions with various pH values. Indentations were made on the (100) plane with the diagonals of the indentation in the (100) direction. The results indicate that a sulfur containing additve in mineral oil increased hardness, a chlorine containing additive in mineral oil decreased hardness, and aqueous solutions of hydrogen chloride decreased hardness. Other environments were found to have little effect on hardness. Mechanically polished surfaces showed larger indentation creep than did as-cleaved surfaces.

Assessment and management of chemical exposure in the Mohs laboratory.

PubMed

Gunson, Todd H; Smith, Harvey R; Vinciullo, Carl

2011-01-01

The correct handling, storage, and disposal of chemicals used in the processing of tissue for Mohs micrographic surgery are essential. To identify the chemicals involved in the preparation of Mohs frozen sections and assess the associated occupational health risks. To quantify exposure levels of hazardous chemicals and ensure that they are minimized. A risk assessment form was completed for each chemical. Atmospheric sampling was performed at our previous laboratory for formaldehyde and volatile organic compounds. These data were used in the design of our new facility, where testing was repeated. Twenty-five chemicals were identified. Ten were classified as hazardous substances, 10 were flammable, six had specific disposal requirements, four were potential carcinogens, and three were potential teratogens. Formaldehyde readings at our previous laboratory were up to eight times the national exposure standard. Testing at the new laboratory produced levels well below the exposure standards. Chemical exposure within the Mohs laboratory can present a significant occupational hazard. Acutely toxic and potentially carcinogenic formaldehyde was found at high levels in a relatively standard laboratory configuration. A laboratory can be designed with a combination of physical environment and operational protocols that minimizes hazards and creates a safe working environment. © 2010 by the American Society for Dermatologic Surgery, Inc.

An Investigation into the Effectiveness of Problem-Based Learning in a Physical Chemistry Laboratory Course

ERIC Educational Resources Information Center

Gurses, Ahmet; Acikyildiz, Metin; Dogar, Cetin; Sozbilir, Mustafa

2007-01-01

The aim of this study was to investigate the effectiveness of a problem-based learning (PBL) approach in a physical chemistry laboratory course. The parameters investigated were students' attitudes towards a chemistry laboratory course, scientific process skills of students and their academic achievement. The design of the study was one group…

Application of failure mode and effect analysis in an assisted reproduction technology laboratory.

PubMed

Intra, Giulia; Alteri, Alessandra; Corti, Laura; Rabellotti, Elisa; Papaleo, Enrico; Restelli, Liliana; Biondo, Stefania; Garancini, Maria Paola; Candiani, Massimo; Viganò, Paola

2016-08-01

Assisted reproduction technology laboratories have a very high degree of complexity. Mismatches of gametes or embryos can occur, with catastrophic consequences for patients. To minimize the risk of error, a multi-institutional working group applied failure mode and effects analysis (FMEA) to each critical activity/step as a method of risk assessment. This analysis led to the identification of the potential failure modes, together with their causes and effects, using the risk priority number (RPN) scoring system. In total, 11 individual steps and 68 different potential failure modes were identified. The highest ranked failure modes, with an RPN score of 25, encompassed 17 failures and pertained to "patient mismatch" and "biological sample mismatch". The maximum reduction in risk, with RPN reduced from 25 to 5, was mostly related to the introduction of witnessing. The critical failure modes in sample processing were improved by 50% in the RPN by focusing on staff training. Three indicators of FMEA success, based on technical skill, competence and traceability, have been evaluated after FMEA implementation. Witnessing by a second human operator should be introduced in the laboratory to avoid sample mix-ups. These findings confirm that FMEA can effectively reduce errors in assisted reproduction technology laboratories. Copyright © 2016 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

A Laboratory Exercise for a College-Level, Introductory Neuroscience Course Demonstrating Effects of Housing Environment on Anxiety and Psychostimulant Sensitivity

PubMed Central

Pritchard, Laurel M.; Van Kempen, Tracey A.; Williams, Heather; Zimmerberg, Betty

2008-01-01

In this paper we describe a lab exercise developed for the Introduction to Neuroscience course at Williams College. One of a series of five labs, this exercise demonstrated several key principles of behavioral neuroscience. In this lab, students explored the effects of post-weaning housing environment on anxiety-like behavior and psychostimulant sensitivity in rodents. The exercise was intended to emphasize the importance and utility of animal models in neuroscience research and to give students hands-on experience with behavioral neuroscience research techniques. Students tested rats reared in social isolation or environmental enrichment for anxiety-like behaviors on the elevated plus maze, and for spontaneous and amphetamine-induced locomotor activity in the open field. They were then asked to analyze pooled class data and prepare a short lab report. Overall, student performance was excellent. This exercise emerged as a class favorite on course evaluations. Interestingly, the first time this exercise was conducted, the effects of environmental enrichment on anxiety-like behaviors and psychostimulant sensitivity were not consistent with those published in previous studies. Key methodological issues that may account for this discrepancy and contribute to successful implementation by other programs are discussed. PMID:23493884

In-Situ VIS/NIR Measurements of Space Environment Effects on Spacecraft Surfaces

NASA Astrophysics Data System (ADS)

Bedard, D.; Seitzer, P.; Willison, A.; Somers, P.

2016-09-01

Laboratory material characterization experiments have shown that passive observational techniques that measure the spectral energy distribution of reflected sunlight from spacecraft and space debris could potentially be used to determine an object's surface compositional make-up and even possibly its orientation. Such techniques, if proven to be reliable and consistent, would represent non-intrusive and cost effective tools that would benefit the overall space situational awareness (SSA) mission. However, to date, observations using either colour photometry or spectrophotometry to determine surface material characteristics of such objects have not produced encouraging results. One common problem that has plagued these attempts is the lack of understanding on how the spectral reflectance of the spacecraft surfaces evolves with time. There are a number of spacecraft materials whose spectral reflectance characteristics have been studied before and after spaceflight in LEO; there are no measurements on how the space environment gradually modifies the spectral scattering characteristics of these materials as a function of time. Furthermore, there are little or no in-situ observations of environmental effects on individually identifiable materials in MEO and GEO. This complicates the task of interpreting the spectral measurements of spatially unresolved spacecraft and orbital debris. This paper presents instrument concepts whose sole purpose will be to acquire on-orbit spectral reflectance measurements, at different observational geometries, of either witness samples or materials covering the surface of the host spacecraft. Such instruments could be flown as a hosted payload on an operational GEO satellite or as a dedicated payload on a microsatellite. Measurements would be acquired over the lifetime of the satellite and would observe how the spectral reflectance characteristics evolve during its lifetime. Furthermore, installation of one of the proposed instruments on

The Benefits and Challenges of an Interfaced Electronic Health Record and Laboratory Information System: Effects on Laboratory Processes.

PubMed

Petrides, Athena K; Bixho, Ida; Goonan, Ellen M; Bates, David W; Shaykevich, Shimon; Lipsitz, Stuart R; Landman, Adam B; Tanasijevic, Milenko J; Melanson, Stacy E F

2017-03-01

- A recent government regulation incentivizes implementation of an electronic health record (EHR) with computerized order entry and structured results display. Many institutions have also chosen to interface their EHR with their laboratory information system (LIS). - To determine the impact of an interfaced EHR-LIS on laboratory processes. - We analyzed several different processes before and after implementation of an interfaced EHR-LIS: the turnaround time, the number of stat specimens received, venipunctures per patient per day, preanalytic errors in phlebotomy, the number of add-on tests using a new electronic process, and the number of wrong test codes ordered. Data were gathered through the LIS and/or EHR. - The turnaround time for potassium and hematocrit decreased significantly (P = .047 and P = .004, respectively). The number of stat orders also decreased significantly, from 40% to 7% for potassium and hematocrit, respectively (P < .001 for both). Even though the average number of inpatient venipunctures per day increased from 1.38 to 1.62 (P < .001), the average number of preanalytic errors per month decreased from 2.24 to 0.16 per 1000 specimens (P < .001). Overall there was a 16% increase in add-on tests. The number of wrong test codes ordered was high and it was challenging for providers to correctly order some common tests. - An interfaced EHR-LIS significantly improved within-laboratory turnaround time and decreased stat requests and preanalytic phlebotomy errors. Despite increasing the number of add-on requests, an electronic add-on process increased efficiency and improved provider satisfaction. Laboratories implementing an interfaced EHR-LIS should be cautious of its effects on test ordering and patient venipunctures per day.

Laboratory determination of effective stress laws for deformation and permeability of chalk

DOE Office of Scientific and Technical Information (OSTI.GOV)

Teufel, L W; Warpinski, N R

1990-01-01

Laboratory deformation and permeability measurements have been made on chalk samples from Ekofisk area fields as a function of confining stress and pore pressure to determine the effective stress laws for chalk. An understanding of the effective stress law is essential to obtain correct reservoir-property data from core analysis and is critical for reservoir management studies and reservoir compaction models. A powerful statistical technique known as the response surface method has been used to analyze our laboratory data determine the form of the effective stress law for deformation and permeability. Experiments were conducted on chalk samples that had a rangemore » of porosities from 15% to 36%, because porosity is the dominant intrinsic property that effects deformation and permeability behavior of chalk. Deformation of a 36% porosity chalk was highly nonlinear, but the effective stress law was linear, with {alpha} equal to about unity. Lower-porosity samples showed linear strain behavior and a linear effective stress law with {alpha} as low as 0.74. Analysis of the effective stress law for permeability is presented only for the lowest porosity chalk sample because changes in permeability in the higher-porosity chalk samples due to increasing confining stress or pore pressure were not were large enough, to deduce meaningful effective stress relationships. 15 refs., 8 figs., 2 tabs.« less

"WGL," a Web Laboratory for Geometry

ERIC Educational Resources Information Center

Quaresma, Pedro; Santos, Vanda; Maric, Milena

2018-01-01

The role of information and communication technologies (ICT) in education is nowadays well recognised. The "Web Geometry Laboratory," is an e-learning, collaborative and adaptive, Web environment for geometry, integrating a well known dynamic geometry system. In a collaborative session, teachers and students, engaged in solving…

Hazardous Environment Robotics

NASA Technical Reports Server (NTRS)

1996-01-01

Jet Propulsion Laboratory (JPL) developed video overlay calibration and demonstration techniques for ground-based telerobotics. Through a technology sharing agreement with JPL, Deneb Robotics added this as an option to its robotics software, TELEGRIP. The software is used for remotely operating robots in nuclear and hazardous environments in industries including automotive and medical. The option allows the operator to utilize video to calibrate 3-D computer models with the actual environment, and thus plan and optimize robot trajectories before the program is automatically generated.

1D and 3D anthropometric data application on public transport vehicle layout and on oil and gas laboratories work environment design.

PubMed

Pastura, F C H; Guimarães, C P; Zamberlan, M C P; Cid, G L; Santos, V S; Streit, P; Paranhos, A G; Cobbe, R T; Cobbe, K T; Batista, D S

2012-01-01

The goal of this paper is to present 1D and 3D anthropometric data applied to two distinct design situations: one related to the interior layout of a public transport vehicle and another one related to oil and gas laboratories work environment design. On this study, the 1D anthropometric data were extracted from the Brazilian anthropometric database developed by INT and the 3D anthropometric data were obtained using a Cyberware 3D whole body scanner. A second purpose of this paper is to present the 3D human scanning data as a tool that can help designers on decision making.

Laboratory Waste Management. A Guidebook.

ERIC Educational Resources Information Center

American Chemical Society, Washington, DC.

A primary goal of the American Chemical Society Task Force on Laboratory Waste Management is to provide laboratories with the information necessary to develop effective strategies and training programs for managing laboratory wastes. This book is intended to present a fresh look at waste management from the laboratory perspective, considering both…

Reactivity of stratospheric aerosols to small amounts of ammonia in the laboratory environment

NASA Technical Reports Server (NTRS)

Hayes, D.; Snetsinger, K.; Ferry, G.; Oberbeck, V.; Farlow, N.

1980-01-01

Trace ammonia in laboratory air reacts easily with sulfuric acid aerosol samples to form crystalline ammonium sulfate. Argon atmospheres, however, protect sampling surfaces from ammonia contamination. It is found that atmospheric aerosols treated in this way contain only sulfuric acid. After an hour exposed to laboratory air, these same samples convert to ammonium sulfate. Aerosol particles have been collected, using argon control, to determine if the absence of crystalline sulfate is common. But so far there is no evidence that aerosols are neutralized by ammonia in the stratosphere.

Spacecraft Environments Interactive: Space Radiation and Its Effects on Electronic System

NASA Technical Reports Server (NTRS)

Howard, J. W., Jr.; Hardage, D. M.

1999-01-01

The natural space environment is characterized by complex and subtle phenomena hostile to spacecraft. Effects of these phenomena impact spacecraft design, development, and operation. Space systems become increasingly susceptible to the space environment as use of composite materials and smaller, faster electronics increases. This trend makes an understanding of space radiation and its effects on electronic systems essential to accomplish overall mission objectives, especially in the current climate of smaller/better/cheaper faster. This primer outlines the radiation environments encountered in space, discusses regions and types of radiation, applies the information to effects that these environments have on electronic systems, addresses design guidelines and system reliability, and stresses the importance of early involvement of radiation specialists in mission planning, system design, and design review (part-by-part verification).

Use of cover habitat by bull trout Salvelinus confluentus and lake trout Salvelinus namaycush in a laboratory environment

USGS Publications Warehouse

Meeuwig, Michael H.; Guy, Christopher S.; Fredenberg, Wade A.

2011-01-01

Lacustrine-adfluvial bull trout, Salvelinus confluentus, migrate from spawning and rearing streams to lacustrine environments as early as age 0. Within lacustrine environments, cover habitat pro- vides refuge from potential predators and is a resource that is competed for if limiting. Competitive inter- actions between bull trout and other species could result in bull trout being displaced from cover habitat, and bull trout may lack evolutionary adaptations to compete with introduced species, such as lake trout, Salvelinus namaycush. A laboratory experiment was performed to examine habitat use and interactions for cover by juvenile (i.e., <80 mm total length) bull trout and lake trout. Differences were observed between bull trout and lake trout in the proportion of time using cover (F1,22.6=20.08, P<0.001) and bottom (F1,23.7 = 37.01, P < 0.001) habitat, with bull trout using cover and bottom habitats more than lake trout. Habitat selection ratios indicated that bull trout avoided water column habitat in the presence of lake trout and that lake trout avoided bottom habitat. Intraspecific and interspecific agonistic interactions were infrequent, but approximately 10 times greater for intraspecific inter- actions between lake trout. Results from this study provide little evidence that juvenile bull trout and lake trout compete for cover, and that species-specific differences in habitat use and selection likely result in habitat partitioning between these species.

Testing for EMC (electromagnetic compatibility) in the clinical environment.