Sample records for laboratory pnnl approved

  1. Radiochemical Processing Laboratory (RPL) at PNNL

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Peurrung, Tony; Clark, Sue; Bryan, Sam

    2017-03-23

    Nuclear research is one of the core components of PNNL's mission. The centerpiece of PNNL's nuclear research is the Radiochemical Processing Laboratory (RPL), a Category 2 nuclear facility with state-of-the-art instrumentation, scientific expertise, and specialized capabilities that enable research with significant quantities of fissionable materials and other radionuclides—from tritium to plutonium. High impact radiological research has been conducted in the RPL since the 1950's, when nuclear weapons and energy production at Hanford were at the forefront of national defense. Since then, significant investments have been made in the RPL to maintain it as a premier nuclear science research facility supportingmore » multiple programs. Most recently, PNNL is developing a world-class analytical electron microscopy facility dedicated to the characterization of radiological materials.« less

  2. Leadership and Stewardship of the Laboratory (Objective 4.1) Notable Outcome - Phase II Alternative Analysis and PNNL Site Plan Recommendation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pittman, Jeffery P.; Cassidy, Stephen R.; Mosey, Whitney LC

    2013-07-31

    Pacific Northwest National Laboratory (PNNL) and the Pacific Northwest Site Office (PNSO) have recently completed an effort to identify the current state of the campus and gaps that exist with regards to space needs, facilities and infrastructure. This effort has been used to establish a campus strategy to ensure PNNL is ready to further the United States (U.S.) Department of Energy (DOE) mission. Ten-year business projections and the impacts on space needs were assessed and incorporated into the long-term facility plans. In identifying/quantifying the space needs for PNNL, the following categories were addressed: Multi-purpose Programmatic (wet chemistry and imaging laboratorymore » space), Strategic (Systems Engineering and Computation Analytics, and Collaboration space), Remediation (space to offset the loss of the Research Technology Laboratory [RTL] Complex due to decontamination and demolition), and Optimization (the exit of older and less cost-effective facilities). The findings of the space assessment indicate a need for wet chemistry space, imaging space, and strategic space needs associated with systems engineering and collaboration space.« less

  3. PNNL Hoisting and Rigging Manual

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Haynie, Todd O.; Fullmer, Michael W.

    2008-12-29

    This manual describes the safe and cost effective operation, inspection, maintenance, and repair requirements for cranes, hoists, fork trucks, slings, rigging hardware, and hoisting equipment. It is intended to be a user's guide to requirements, codes, laws, regulations, standards, and practices that apply to Pacific Northwest National Laboratory (PNNL) and its subcontractors.

  4. PNNL Results from 2010 CALIBAN Criticality Accident Dosimeter Intercomparison Exercise

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hill, Robin L.; Conrady, Matthew M.

    2011-10-28

    This document reports the results of the Hanford personnel nuclear accident dosimeter (PNAD) and fixed nuclear accident dosimeter (FNAD) during a criticality accident dosimeter intercomparison exercise at the CEA Valduc Center on September 20-23, 2010. Pacific Northwest National Laboratory (PNNL) participated in a criticality accident dosimeter intercomparison exercise at the Commissariat a Energie Atomique (CEA) Valduc Center near Dijon, France on September 20-23, 2010. The intercomparison exercise was funded by the U.S. Department of Energy, Nuclear Criticality Safety Program, with Lawrence Livermore National Laboratory as the lead Laboratory. PNNL was one of six invited DOE Laboratory participants. The other participatingmore » Laboratories were: Lawrence Livermore National Laboratory (LLNL), Los Alamos National Laboratory (LANL), Savannah River Site (SRS), the Y-12 National Security Complex at Oak Ridge, and Sandia National Laboratory (SNL). The goals of PNNL's participation in the intercomparison exercise were to test and validate the procedures and algorithm currently used for the Hanford personnel nuclear accident dosimeters (PNADs) on the metallic reactor, CALIBAN, to test exposures to PNADs from the side and from behind a phantom, and to test PNADs that were taken from a historical batch of Hanford PNADs that had varying degrees of degradation of the bare indium foil. Similar testing of the PNADs was done on the Valduc SILENE test reactor in 2009 (Hill and Conrady, 2010). The CALIBAN results are reported here.« less

  5. EMP Attachment 3 DOE-SC PNNL Site Dose Assessment Guidance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Snyder, Sandra F.

    2011-12-21

    This Dose Assessment Guidance (DAG) describes methods to use to determine the Maximally-Exposed Individual (MEI) location and to estimate dose impact to that individual under the U.S. Department of Energy Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Site Environmental Monitoring Plan (EMP). This guidance applies to public dose from radioactive material releases to the air from PNNL Site operations. This document is an attachment to the Pacific Northwest National Laboratory (PNNL) Environmental Monitoring Plan (EMP) and describes dose assessment guidance for radiological air emissions. The impact of radiological air emissions from the U.S. Department of Energy Office ofmore » Science (DOE-SC) PNNL Site is indicated by dose estimates to a maximally exposed member of the public, referred to as the maximally exposed individual (MEI). Reporting requirements associated with dose to members of the public from radiological air emissions are in 40 CFR Part 61.94, WAC 246-247-080, and DOE Order 458.1. The DOE Order and state standards for dose from radioactive air emissions are consistent with U.S. Environmental Protection Agency (EPA) dose standards in 40 CFR 61.92 (i.e., 10 mrem/yr to a MEI). Despite the fact that the current Contract Requirements Document (CRD) for the DOE-SC PNNL Site operations does not include the requirement to meet DOE CRD 458.1, paragraph 2.b, public dose limits, the DOE dose limits would be met when EPA limits are met.« less

  6. From Dr. Steven Ashby, Director of PNNL

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ashby, Steven

    Powered by the creativity and imagination of more than 4,000 exceptional scientists, engineers and support professionals, at PNNL we advance the frontiers of science and address some of the most challenging problems in energy, the environment and national security. As DOE’s premier chemistry, environmental sciences and data analytics laboratory, we provide national leadership in four areas: deepening our understanding of climate science; inventing the future power grid; preventing nuclear proliferation; and speeding environmental remediation. Other areas where we make important contributions include energy storage, microbial biology and cyber security. PNNL also is home to EMSL (the Environmental Molecular Sciences Laboratory),more » one of DOE’s scientific user facilities. We apply these science strengths to address both national and international problems in complex adaptive systems that are too difficult for one institution to tackle alone. Take earth systems, for instance. The earth is a complex adaptive system because it involves everything from climate and microbial communities in the soil to emissions from cars and coal-powered industrial plants. All of these factors and others ultimately influence not only our environment and overall quality of life, but cause the earth to adapt in ways that must be further addressed. PNNL researchers are playing a vital role in finding solutions across every area of this complex adaptive system.« less

  7. Changing Safety Culture, One Step at a Time: The Value of the DOE-VPP Program at PNNL

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wright, Patrick A.; Isern, Nancy G.

    2005-02-01

    The primary value of the Pacific Northwest National Laboratory (PNNL) Voluntary Protection Program (VPP) is the ongoing partnership between management and staff committed to change Laboratory safety culture one step at a time. VPP enables PNNL's safety and health program to transcend a top-down, by-the-book approach to safety, and it also raises grassroots safety consciousness by promoting a commitment to safety and health 24 hours a day, 7 days a week. PNNL VPP is a dynamic, evolving program that fosters innovative approaches to continuous improvement in safety and health performance at the Laboratory.

  8. 7 CFR 996.22 - USDA-approved laboratory.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false USDA-approved laboratory. 996.22 Section 996.22... STANDARDS FOR DOMESTIC AND IMPORTED PEANUTS MARKETED IN THE UNITED STATES Definitions § 996.22 USDA-approved laboratory. USDA-approved laboratory means laboratories approved by the Science and Technology Programs...

  9. 7 CFR 996.22 - USDA-approved laboratory.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false USDA-approved laboratory. 996.22 Section 996.22... STANDARDS FOR DOMESTIC AND IMPORTED PEANUTS MARKETED IN THE UNITED STATES Definitions § 996.22 USDA-approved laboratory. USDA-approved laboratory means laboratories approved by the Science and Technology Programs...

  10. 7 CFR 996.22 - USDA-approved laboratory.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false USDA-approved laboratory. 996.22 Section 996.22... STANDARDS FOR DOMESTIC AND IMPORTED PEANUTS MARKETED IN THE UNITED STATES Definitions § 996.22 USDA-approved laboratory. USDA-approved laboratory means laboratories approved by the Science and Technology Programs...

  11. 7 CFR 996.22 - USDA-approved laboratory.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false USDA-approved laboratory. 996.22 Section 996.22... STANDARDS FOR DOMESTIC AND IMPORTED PEANUTS MARKETED IN THE UNITED STATES Definitions § 996.22 USDA-approved laboratory. USDA-approved laboratory means laboratories approved by the Science and Technology Programs...

  12. 7 CFR 996.22 - USDA-approved laboratory.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... STANDARDS FOR DOMESTIC AND IMPORTED PEANUTS MARKETED IN THE UNITED STATES Definitions § 996.22 USDA-approved laboratory. USDA-approved laboratory means laboratories approved by the Science and Technology Programs...

  13. Technical Basis for PNNL Beryllium Inventory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Johnson, Michelle Lynn

    2014-07-09

    The Department of Energy (DOE) issued Title 10 of the Code of Federal Regulations Part 850, “Chronic Beryllium Disease Prevention Program” (the Beryllium Rule) in 1999 and required full compliance by no later than January 7, 2002. The Beryllium Rule requires the development of a baseline beryllium inventory of the locations of beryllium operations and other locations of potential beryllium contamination at DOE facilities. The baseline beryllium inventory is also required to identify workers exposed or potentially exposed to beryllium at those locations. Prior to DOE issuing 10 CFR 850, Pacific Northwest Nuclear Laboratory (PNNL) had documented the beryllium characterizationmore » and worker exposure potential for multiple facilities in compliance with DOE’s 1997 Notice 440.1, “Interim Chronic Beryllium Disease.” After DOE’s issuance of 10 CFR 850, PNNL developed an implementation plan to be compliant by 2002. In 2014, an internal self-assessment (ITS #E-00748) of PNNL’s Chronic Beryllium Disease Prevention Program (CBDPP) identified several deficiencies. One deficiency is that the technical basis for establishing the baseline beryllium inventory when the Beryllium Rule was implemented was either not documented or not retrievable. In addition, the beryllium inventory itself had not been adequately documented and maintained since PNNL established its own CBDPP, separate from Hanford Site’s program. This document reconstructs PNNL’s baseline beryllium inventory as it would have existed when it achieved compliance with the Beryllium Rule in 2001 and provides the technical basis for the baseline beryllium inventory.« less

  14. PNNL Supports Hanford Waste Treatment

    ScienceCinema

    None

    2018-04-16

    For more than 40 years, technical assistance from PNNL has supported the operations and processing of Hanford tank waste. Our expertise in tank waste chemistry, fluid dynamics and scaling, waste forms, and safety bases has helped to shape the site’s waste treatment baseline and solve operational challenges. The historical knowledge and unique scientific and technical expertise at PNNL are essential to the success of the Hanford mission.

  15. PNNL Apatite Investigation at 100-NR-2 Quality Assurance Project Plan

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fix, N. J.

    In 2004, the U.S. Department of Energy, Fluor Hanford, Inc., Pacific Northwest National Laboratory (PNNL), and the Washington Department of Ecology agreed that the long-term strategy for groundwater remediation at the 100-N Area would include apatite sequestration as the primary treatment, followed by a secondary treatment if necessary. Since then, the agencies have worked together to agree on which apatite sequestration technology has the greatest chance of reducing strontium-90 flux to the Columbia River. This Quality Assurance Project Plan provides the quality assurance requirements and processes that will be followed by staff working on the PNNL Apatite Investigation at 100-NR-2more » Project. The plan is designed to be used exclusively by project staff.« less

  16. 40 CFR 141.705 - Approved laboratories.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Cryptosporidium analysis by an equivalent State laboratory certification program. (b) E. coli. Any laboratory... coliform or fecal coliform analysis under § 141.74 is approved for E. coli analysis under this subpart when the laboratory uses the same technique for E. coli that the laboratory uses for § 141.74. (c...

  17. 40 CFR 141.705 - Approved laboratories.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Cryptosporidium analysis by an equivalent State laboratory certification program. (b) E. coli. Any laboratory... coliform or fecal coliform analysis under § 141.74 is approved for E. coli analysis under this subpart when the laboratory uses the same technique for E. coli that the laboratory uses for § 141.74. (c...

  18. 40 CFR 141.705 - Approved laboratories.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Cryptosporidium analysis by an equivalent State laboratory certification program. (b) E. coli. Any laboratory... coliform or fecal coliform analysis under § 141.74 is approved for E. coli analysis under this subpart when the laboratory uses the same technique for E. coli that the laboratory uses for § 141.74. (c...

  19. 40 CFR 141.705 - Approved laboratories.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Cryptosporidium analysis by an equivalent State laboratory certification program. (b) E. coli. Any laboratory... coliform or fecal coliform analysis under § 141.74 is approved for E. coli analysis under this subpart when the laboratory uses the same technique for E. coli that the laboratory uses for § 141.74. (c...

  20. 40 CFR 141.705 - Approved laboratories.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Cryptosporidium analysis by an equivalent State laboratory certification program. (b) E. coli. Any laboratory... coliform or fecal coliform analysis under § 141.74 is approved for E. coli analysis under this subpart when the laboratory uses the same technique for E. coli that the laboratory uses for § 141.74. (c...

  1. CBB Portal @ PNNL

    Science.gov Websites

    Search PNNL Home About Research Publications Jobs News Contacts Computational Biology and Bioinformatics , and engineering to transform the data into knowledge. This new quantitative, predictive biology is to empirical modeling and physics-based simulations. CBB research seeks to: Understand. Understanding

  2. Preparing PNNL Reports with LaTeX

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Waichler, Scott R.

    2005-06-01

    LaTeX is a mature document preparation system that is the standard in many scientific and academic workplaces. It has been used extensively by scattered individuals and research groups within PNNL for years, but until now there have been no centralized or lab-focused resources to help authors and editors. PNNL authors and editors can produce correctly formatted PNNL or PNWD reports using the LaTeX document preparation system and the available template files. Please visit the PNNL-LaTeX Project (http://stidev.pnl.gov/resources/latex/, inside the PNNL firewall) for additional information and files. In LaTeX, document content is maintained separately from document structure for the most part.more » This means that the author can easily produce the same content in different formats and, more importantly, can focus on the content and write it in a plain text file that doesn't go awry, is easily transferable, and won't become obsolete due to software changes. LaTeX produces the finest print quality output; its typesetting is noticeably better than that of MS Word. This is particularly true for mathematics, tables, and other types of special text. Other benefits of LaTeX: easy handling of large numbers of figures and tables; automatic and error-free captioning, citation, cross-referencing, hyperlinking, and indexing; excellent published and online documentation; free or low-cost distributions for Windows/Linux/Unix/Mac OS X. This document serves two purposes: (1) it provides instructions to produce reports formatted to PNNL requirements using LaTeX, and (2) the document itself is in the form of a PNNL report, providing examples of many solved formatting challenges. Authors can use this document or its skeleton version (with formatting examples removed) as the starting point for their own reports. The pnnreport.cls class file and pnnl.bst bibliography style file contain the required formatting specifications for reports to the Department of Energy. Options are also

  3. Data Quality Objectives Supporting Radiological Air Emissions Monitoring for the PNNL Richland Campus

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Snyder, Sandra F.; Moleta, Donna Grace L.; Meier, Kirsten M.

    This is the second revision of the DQO Supporting Radiological Air Emissions Monitoring for the Pacific Northwest National Laboratory Richland Campus. In January 2017, the PNNL Richland Campus expanded to the north by 0.35 km 2 (85.6 acres). Under the requirements of Washington State Department of Health Radioactive Air Emissions License (RAEL)-005, the PNNL Campus operates and maintains a radiological air monitoring program. This revision documents and evaluates the newly acquired acreage while also removing recreational land at the southwest, and also re-examines all active radioactive emission units on the PNNL Campus. No buildings are located on this new Campusmore » land, which was transferred from the U.S. DOE Hanford Site. Additionally, this revision includes information regarding the background monitoring station PNL-5 in Benton City, Washington, which became active in October 2016. The key purpose of this revision is to determine the adequacy of the existing environmental surveillance stations to monitor radiological air emissions in light of this northern boundary change.« less

  4. Germanium detectors in homeland security at PNNL

    DOE PAGES

    Stave, S.

    2015-05-01

    Neutron and gamma-ray detection is used for non-proliferation and national security applications. While lower energy resolution detectors such as NaI(Tl) have their place, high purity germanium (HPGe) also has a role to play. A detection with HPGe is often a characterization due to the very high energy resolution. However, HPGe crystals remain small and expensive leaving arrays of smaller crystals as an excellent solution. PNNL has developed two similar HPGe arrays for two very different applications. One array, the Multisensor Aerial Radiation Survey (MARS) detector is a fieldable array that has been tested on trucks, boats, and helicopters. The CASCADESmore » HPGe array is an array designed to assay samples in a low background environment. The history of HPGe arrays at PNNL and the development of MARS and CASCADES will be detailed in this paper along with some of the other applications of HPGe at PNNL.« less

  5. [Approval of ISO/IEC 17025 and quality control of laboratory testing].

    PubMed

    Yamamoto, Shigeki; Asakura, Hiroshi; Machii, Kenji; Igimi, Shizunobu

    2010-01-01

    First section of Division of Biomedical Food Research, National Institute of Health Sciences (NIHS) was approved by ISO/IEC 17025 as a laboratory having an appropriate laboratory testing technique. NIHS is the first national laboratory approved by ISO/IEC 17025. NIHS has also been accepted the appropriate technique and facility for the BSL3 level pathogens by ISO/IEC 17025. NIHS is necessary to take an external audit almost every year. This approval is renewed every 4 years.

  6. 75 FR 1799 - Agency Information Collection Activities: Accreditation of Commercial Laboratories and Approval...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-13

    ... Activities: Accreditation of Commercial Laboratories and Approval of Commercial Gaugers AGENCY: U.S. Customs... Reduction Act: Accreditation of Commercial Laboratories and Approval of Commercial Gaugers. This is a.... Title: Accreditation of Commercial Laboratories and Approval of Commercial Gaugers. OMB Number: 1651...

  7. PNNL Development and Analysis of Material-Based Hydrogen Storage Systems for the Hydrogen Storage Engineering Center of Excellence

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brooks, Kriston P.; Alvine, Kyle J.; Johnson, Kenneth I.

    The Hydrogen Storage Engineering Center of Excellence is a team of universities, industrial corporations, and federal laboratories with the mandate to develop lower-pressure, materials-based, hydrogen storage systems for hydrogen fuel cell light-duty vehicles. Although not engaged in the development of new hydrogen storage materials themselves, it is an engineering center that addresses engineering challenges associated with the currently available hydrogen storage materials. Three material-based approaches to hydrogen storage are being researched: 1) chemical hydrogen storage materials 2) cryo-adsorbents, and 3) metal hydrides. As a member of this Center, Pacific Northwest National Laboratory (PNNL) has been involved in the design andmore » evaluation of systems developed with each of these three hydrogen storage materials. This report is a compilation of the work performed by PNNL for this Center.« less

  8. Energy and Water Conservation Assessment of the Radiochemical Processing Laboratory (RPL) at Pacific Northwest National Laboratory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Johnson, Stephanie R.; Koehler, Theresa M.; Boyd, Brian K.

    2014-05-31

    This report summarizes the results of an energy and water conservation assessment of the Radiochemical Processing Laboratory (RPL) at Pacific Northwest National Laboratory (PNNL). The assessment was performed in October 2013 by engineers from the PNNL Building Performance Team with the support of the dedicated RPL staff and several Facilities and Operations (F&O) department engineers. The assessment was completed for the Facilities and Operations (F&O) department at PNNL in support of the requirements within Section 432 of the Energy Independence and Security Act (EISA) of 2007.

  9. Least-Squares Neutron Spectral Adjustment with STAYSL PNNL

    NASA Astrophysics Data System (ADS)

    Greenwood, L. R.; Johnson, C. D.

    2016-02-01

    The STAYSL PNNL computer code, a descendant of the STAY'SL code [1], performs neutron spectral adjustment of a starting neutron spectrum, applying a least squares method to determine adjustments based on saturated activation rates, neutron cross sections from evaluated nuclear data libraries, and all associated covariances. STAYSL PNNL is provided as part of a comprehensive suite of programs [2], where additional tools in the suite are used for assembling a set of nuclear data libraries and determining all required corrections to the measured data to determine saturated activation rates. Neutron cross section and covariance data are taken from the International Reactor Dosimetry File (IRDF-2002) [3], which was sponsored by the International Atomic Energy Agency (IAEA), though work is planned to update to data from the IAEA's International Reactor Dosimetry and Fusion File (IRDFF) [4]. The nuclear data and associated covariances are extracted from IRDF-2002 using the third-party NJOY99 computer code [5]. The NJpp translation code converts the extracted data into a library data array format suitable for use as input to STAYSL PNNL. The software suite also includes three utilities to calculate corrections to measured activation rates. Neutron self-shielding corrections are calculated as a function of neutron energy with the SHIELD code and are applied to the group cross sections prior to spectral adjustment, thus making the corrections independent of the neutron spectrum. The SigPhi Calculator is a Microsoft Excel spreadsheet used for calculating saturated activation rates from raw gamma activities by applying corrections for gamma self-absorption, neutron burn-up, and the irradiation history. Gamma self-absorption and neutron burn-up corrections are calculated (iteratively in the case of the burn-up) within the SigPhi Calculator spreadsheet. The irradiation history corrections are calculated using the BCF computer code and are inserted into the SigPhi Calculator

  10. PNNL Tests Fish Passage System

    ScienceCinema

    Colotelo, Alison

    2018-01-16

    Scientists from PNNL are testing a fish transportation system developed by Whooshh Innovations. The Whooshh system uses a flexible tube that works a bit like a vacuum, guiding fish over hydroelectric dams or other structures. Compared to methods used today, this system could save money while granting fish quicker, safer passage through dams and hatcheries.

  11. PNNL Tests Fish Passage System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Colotelo, Alison

    2015-03-13

    Scientists from PNNL are testing a fish transportation system developed by Whooshh Innovations. The Whooshh system uses a flexible tube that works a bit like a vacuum, guiding fish over hydroelectric dams or other structures. Compared to methods used today, this system could save money while granting fish quicker, safer passage through dams and hatcheries.

  12. PNNL streamlines energy-guzzling computers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beckman, Mary T.; Marquez, Andres

    In a room the size of a garage, two rows of six-foot-tall racks holding supercomputer hard drives sit back-to-back. Thin tubes and wires snake off the hard drives, slithering into the corners. Stepping between the rows, a rush of heat whips around you -- the air from fans blowing off processing heat. But walk farther in, between the next racks of hard drives, and the temperature drops noticeably. These drives are being cooled by a non-conducting liquid that runs right over the hardworking processors. The liquid carries the heat away in tubes, saving the air a few degrees. This ismore » the Energy Smart Data Center at Pacific Northwest National Laboratory. The bigger, faster, and meatier supercomputers get, the more energy they consume. PNNL's Andres Marquez has developed this test bed to learn how to train the behemoths in energy efficiency. The work will help supercomputers perform better as well. Processors have to keep cool or suffer from "thermal throttling," says Marquez. "That's the performance threshold where the computer is too hot to run well. That threshold is an industry secret." The center at EMSL, DOE's national scientific user facility at PNNL, harbors several ways of experimenting with energy usage. For example, the room's air conditioning is isolated from the rest of EMSL -- pipes running beneath the floor carry temperature-controlled water through heat exchangers to cooling towers outside. "We can test whether it's more energy efficient to cool directly on the processing chips or out in the water tower," says Marquez. The hard drives feed energy and temperature data to a network server running specially designed software that controls and monitors the data center. To test the center’s limits, the team runs the processors flat out – not only on carefully controlled test programs in the Energy Smart computers, but also on real world software from other EMSL research, such as regional weather forecasting models. Marquez's group is also

  13. 78 FR 79656 - Notice of Request for Approval of an Information Collection; Approval of Laboratories for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-31

    ...In accordance with the Paperwork Reduction Act of 1995, this notice announces the Animal and Plant Health Inspection Service's intention to request approval of a new information collection for the approval of laboratories for conducting aquatic animal tests for export health certificates.

  14. 76 FR 4710 - Accreditation and Approval of Laboratory Service, Inc., as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-26

    ... Laboratory Service, Inc., as a Commercial Gauger and Laboratory AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION: Notice of accreditation and approval of Laboratory Service, Inc., as a commercial gauger and laboratory. SUMMARY: Notice is hereby given that, pursuant to 19 CFR 151.12...

  15. 42 CFR 493.645 - Additional fee(s) applicable to approved State laboratory programs and laboratories issued a...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS General Administration § 493.645 Additional fee(s) applicable to approved State laboratory programs and... laboratory programs and laboratories issued a certificate of accreditation, certificate of waiver, or...

  16. PNNL Provides Catalyst for Sustainable Propylene Glycol Production

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Madison, Alison L.; Lund, Eric C.

    2012-02-28

    Submission for annual FLC magazine publication, Technology for Today, featuring technologies transferred by federal labs. Subject: PNNL transfer of Propylene Glycol from Renewable Sources catalytic process to Archer Daniels Midland Company.

  17. PNNL Measurement Results for the 2016 Criticality Accident Dosimetry Exercise at the Nevada National Security Stite (IER-148)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rathbone, Bruce A.; Morley, Shannon M.; Stephens, John A.

    The Pacific Northwest National Laboratory (PNNL) participated in a criticality accident dosimetry intercomparison exercise held at the Nevada National Security Site (NNSS) May 24-27, 2016. The exercise was administered by Lawrence Livermore National Laboratory (LLNL) and consisted of three exposures performed using the Godiva-IV critical assembly housed in the Device Assembly Facility (DAF) located on the NNSS site. The exercise allowed participants to test the ability of their nuclear accident dosimeters to meet the performance criteria in ANSI/HPS N13.3-2013, Dosimetry for Criticality Accidents and to obtain new measurement data for use in revising dose calculation methods and quick sort screeningmore » methods where appropriate. PNNL participated with new prototype Personal Nuclear Accident Dosimeter (PNAD) and Fixed Nuclear Accident Dosimeter (FNAD) designs as well as the existing historical PNAD design. The new prototype designs incorporate optically stimulated luminescence (OSL) dosimeters in place of thermoluminescence dosimeters (TLDs), among other design changes, while retaining the same set of activation foils historically used. The default dose calculation methodology established decades ago for use with activation foils in PNNL PNADs and FNADs was used to calculate neutron dose results for both the existing and prototype dosimeters tested in the exercise. The results indicate that the effective cross sections and/or dose conversion factors used historically need to be updated to accurately measure the operational quantities recommended for nuclear accident dosimetry in ANSI/HPS N13.3-2013 and to ensure PNAD and FNAD performance meets the ANSI/HPS N13.3-2013 performance criteria. The operational quantities recommended for nuclear accident dosimetry are personal absorbed dose, Dp(10), and ambient absorbed dose, D*(10).« less

  18. 7 CFR 3300.91 - List of approved testing stations, approved testing laboratories, and fees for certificates.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... CARRIAGE OF PERISHABLE FOODSTUFFS AND ON THE SPECIAL EQUIPMENT TO BE USED FOR SUCH CARRIAGE (ATP... testing stations, approved testing laboratories, and fees for certificates. A current list of U.S. ATP testing stations, U.S. ATP testing laboratories, and fees for issuance of U.S. ATP certificates may be...

  19. 7 CFR 3300.91 - List of approved testing stations, approved testing laboratories, and fees for certificates.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... CARRIAGE OF PERISHABLE FOODSTUFFS AND ON THE SPECIAL EQUIPMENT TO BE USED FOR SUCH CARRIAGE (ATP... testing stations, approved testing laboratories, and fees for certificates. A current list of U.S. ATP testing stations, U.S. ATP testing laboratories, and fees for issuance of U.S. ATP certificates may be...

  20. 7 CFR 3300.91 - List of approved testing stations, approved testing laboratories, and fees for certificates.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... CARRIAGE OF PERISHABLE FOODSTUFFS AND ON THE SPECIAL EQUIPMENT TO BE USED FOR SUCH CARRIAGE (ATP... testing stations, approved testing laboratories, and fees for certificates. A current list of U.S. ATP testing stations, U.S. ATP testing laboratories, and fees for issuance of U.S. ATP certificates may be...

  1. 7 CFR 3300.91 - List of approved testing stations, approved testing laboratories, and fees for certificates.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... CARRIAGE OF PERISHABLE FOODSTUFFS AND ON THE SPECIAL EQUIPMENT TO BE USED FOR SUCH CARRIAGE (ATP... testing stations, approved testing laboratories, and fees for certificates. A current list of U.S. ATP testing stations, U.S. ATP testing laboratories, and fees for issuance of U.S. ATP certificates may be...

  2. 7 CFR 3300.91 - List of approved testing stations, approved testing laboratories, and fees for certificates.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... CARRIAGE OF PERISHABLE FOODSTUFFS AND ON THE SPECIAL EQUIPMENT TO BE USED FOR SUCH CARRIAGE (ATP... testing stations, approved testing laboratories, and fees for certificates. A current list of U.S. ATP testing stations, U.S. ATP testing laboratories, and fees for issuance of U.S. ATP certificates may be...

  3. Economic Impact of Pacific Northwest National Laboratory on the State of Washington in Fiscal Year 2013

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scott, Michael J.; Niemeyer, Jackie M.

    Pacific Northwest National Laboratory (PNNL) is a large economic entity, with $1.06 billion in annual funding, $936 million in total spending, and 4,344 employees in fiscal year (FY) 2013. Four thousand, one hundred and one (4,101) employees live in Washington State. The Laboratory directly and indirectly supports almost $1.31 billion in economic output, 6,802 jobs, and $514 million in Washington State wage income from current operations. The state also gains more than $1.21 billion in output, more than 6,400 jobs, and $459 million in income through closely related economic activities, such as visitors, health care spending, spending by resident retirees,more » and spinoff companies. PNNL affects Washington’s economy through commonly recognized economic channels, including spending on payrolls and other goods and services that support Laboratory operations. Less-commonly recognized channels also have their own impacts and include company-supported spending on health care for its staff members and retirees, spending of its resident retirees, Laboratory visitor spending, and the economic activities in a growing constellation of “spinoff” companies founded on PNNL research, technology, and managerial expertise. PNNL also has a significant impact on science and technology education and community nonprofit organizations. PNNL is an active participant in the future scientific enterprise in Washington with the state’s K-12 schools, colleges, and universities. The Laboratory sends staff members to the classroom and brings hundreds of students to the PNNL campus to help train the next generation of scientists, engineers, mathematicians, and technicians. This investment in human capital, though difficult to measure in terms of current dollars of economic output, is among the important lasting legacies of the Laboratory. Finally, PNNL contributes to the local community with millions of dollars’ worth of cash and in-kind corporate and staff contributions, all of

  4. Task 6 - Subtask 1: PNNL Visit by JAEA Researchers to Evaluate the Feasibility of the FLESCOT Code for the Future JAEA Use for the Fukushima Surface Water Environmental Assessment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Onishi, Yasuo

    Four Japan Atomic Energy Agency (JAEA) researchers visited Pacific Northwest National Laboratory (PNNL) for seven working days and have evaluated the suitability and adaptability of FLESCOT to a JAEA’s supercomputer system to effectively simulate cesium behavior in dam reservoirs, river mouths, and coastal areas in Fukushima contaminated by the Fukushima Daiichi nuclear accident. PNNL showed the following to JAEA visitors during the seven-working day period: FLESCOT source code; User’s manual; FLESCOT description – Program structure – Algorism – Solver – Boundary condition handling – Data definition – Input and output methods – How to run. During the visit, JAEA hadmore » access to FLESCOT to run with an input data set to evaluate the capacity and feasibility of adapting it to a JAEA super computer with massive parallel processors. As a part of this evaluation, PNNL ran FLESCOT for sample cases of the contaminant migration simulation to further describe FLESCOT in action. JAEA and PNNL researchers also evaluated time spent for each subroutine of FLESCOT, and the JAEA researcher implemented some initial parallelization schemes to FLESCOT. Based on this code evaluation, JAEA and PNNL determined that FLESCOT is: applicable to Fukushima lakes/dam reservoirs, river mouth areas, and coastal water; and feasible to implement parallelization for the JAEA supercomputer. In addition, PNNL and JAEA researchers discussed molecular modeling approaches on cesium adsorption mechanisms to enhance the JAEA molecular modeling activities. PNNL and JAEA also discussed specific collaboration of molecular and computational modeling activities.« less

  5. 2010 Ecological Survey of the Pacific Northwest National Laboratory Site

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chamness, Michele A.; Perry, Christopher; Downs, Janelle L.

    The U.S. Department of Energy (DOE) Pacific Northwest Site Office (PNSO) oversees and manages the DOE contract for the Pacific Northwest National Laboratory (PNNL), a DOE Office of Science multi-program laboratory located in Richland, Washington. PNSO is responsible for ensuring that all activities conducted on the PNNL Site comply with applicable laws, policies, and DOE orders. The DOE Pacific Northwest Site Office Cultural and Biological Resources Management Plan (DOE/PNSO 2008) addresses the requirement for annual surveys and monitoring for species of concern and to identify and map invasive species. In addition to the requirement for an annual survey, proposed projectmore » activities must be reviewed to assess any potential environmental consequences of conducting the project. The assessment process requires a thorough understanding of the resources present, the potential impacts of a proposed action to those resources, and the ultimate consequences of those actions. The PNNL Site is situated on the southeastern corner of the DOE Hanford Site, located at the north end of the city of Richland in south-central Washington. The site is bordered on the east by the Columbia River, on the west by Stevens Drive, and on the north by the Hanford Site 300 Area (Figure 1). The environmental setting of the PNNL Site is described in Larson and Downs (2009). There are currently two facilities on the PNNL Site: the William R. Wiley Environmental Molecular Sciences Laboratory (EMSL), and the recently completed Physical Sciences Facility (PSF). This report describes the results of the annual survey of the biological resources found on the undeveloped portions of the PNNL Site in 2010. A brief description of the methods PNNL ecologists used to conduct the surveys and the results of the surveys are presented. Actions taken to fully delineate noxious weed populations discovered in 2009 and efforts in 2010 to control those weeds also are described. Appendix A provides a list of

  6. 2011 Annual Ecological Survey: Pacific Northwest National Laboratory Site

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Becker, James M.; Chamness, Michele A.

    The U.S. Department of Energy (DOE) Pacific Northwest Site Office (PNSO) oversees and manages the DOE contract for the Pacific Northwest National Laboratory (PNNL), a DOE Office of Science multi-program laboratory located in Richland, Washington. PNSO is responsible for ensuring that all activities conducted on the PNNL site comply with applicable laws, policies, and DOE Orders. The DOE Pacific Northwest Site Office Cultural and Biological Resources Management Plan (DOE/PNSO 2008) addresses the requirement for annual surveys and monitoring for species of concern and to identify and map invasive species. In addition to the requirement for an annual survey, proposed projectmore » activities must be reviewed to assess any potential environmental consequences of conducting the project. The assessment process requires a thorough understanding of the resources present, the potential impacts of a proposed action to those resources, and the ultimate consequences of those actions. The PNNL site is situated on the southeastern corner of the DOE Hanford Site, located at the north end of the city of Richland in south-central Washington. The site is bordered on the east by the Columbia River, on the west by Stevens Drive, and on the north by the Hanford Site 300 Area (Figure 1). The environmental setting of the PNNL site is described in Larson and Downs (2009). There are currently two facilities on the PNNL site: the William R. Wiley Environmental Molecular Sciences Laboratory and the Physical Sciences Facility. This report describes the annual survey of biological resources found on the undeveloped upland portions of the PNNL site. The annual survey is comprised of a series of individual field surveys conducted on various days in late May and throughout June 2011. A brief description of the methods PNNL ecologists used to conduct the baseline surveys and a summary of the results of the surveys are presented. Appendix A provides a list of plant and animal species identified

  7. International Safeguards and the Pacific Northwest National Laboratory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Olsen, Khris B.; Smith, Leon E.; Frazar, Sarah L.

    Established in 1965, Pacific Northwest National Laboratory’s (PNNL) strong technical ties and shared heritage with the nearby U.S. Department of Energy Hanford Site were central to the early development of expertise in nuclear fuel cycle signatures, separations chemistry, plutonium chemistry, environmental monitoring, modeling and analysis of reactor systems, and nuclear material safeguards and security. From these Hanford origins, PNNL has grown into a multi-program science and engineering enterprise that utilizes this diversity to strengthen the international safeguards regime. Today, PNNL supports the International Atomic Energy Agency (IAEA) in its mission to provide assurances to the international community that nations domore » not use nuclear materials and equipment outside of peaceful uses. PNNL also serves in the IAEA’s Network of Analytical Laboratories (NWAL) by providing analysis of environmental samples gathered around the world. PNNL is involved in safeguards research and development activities in support of many U.S. Government programs such as the National Nuclear Security Administration’s (NNSA) Office of Research and Development, NNSA Office of Nonproliferation and Arms Control, and the U.S. Support Program to IAEA Safeguards. In addition to these programs, PNNL invests internal resources including safeguards-specific training opportunities for staff, and laboratory-directed research and development funding to further ideas that may grow into new capabilities. This paper and accompanying presentation highlight some of PNNL’s contributions in technology development, implementation concepts and approaches, policy, capacity building, and human capital development, in the field of international safeguards.« less

  8. 75 FR 70939 - Approval of SAYBOLT LP, as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-19

    ... Commercial Gauger and Laboratory AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION: Notice of accreditation and approval of Saybolt LP, as a commercial gauger and laboratory... wishing to employ this entity to conduct laboratory analyses and gauger services should request and...

  9. Customer satisfaction assessment at the Pacific Northwest National Laboratory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    DN Anderson; ML Sours

    2000-03-23

    The Pacific Northwest National Laboratory (PNNL) is developing and implementing a customer satisfaction assessment program (CSAP) to assess the quality of research and development provided by the laboratory. This report presents the customer survey component of the PNNL CSAP. The customer survey questionnaire is composed of two major sections: Strategic Value and Project Performance. Both sections contain a set of questions that can be answered with a 5-point Likert scale response. The strategic value section consists of five questions that are designed to determine if a project directly contributes to critical future national needs. The project Performance section consists ofmore » nine questions designed to determine PNNL performance in meeting customer expectations. A statistical model for customer survey data is developed and this report discusses how to analyze the data with this model. The properties of the statistical model can be used to establish a gold standard or performance expectation for the laboratory, and then to assess progress. The gold standard is defined using laboratory management input--answers to four questions, in terms of the information obtained from the customer survey: (1) What should the average Strategic Value be for the laboratory project portfolio? (2) What Strategic Value interval should include most of the projects in the laboratory portfolio? (3) What should average Project Performance be for projects with a Strategic Value of about 2? (4) What should average Project Performance be for projects with a Strategic Value of about 4? To be able to provide meaningful answers to these questions, the PNNL customer survey will need to be fully implemented for several years, thus providing a link between management perceptions of laboratory performance and customer survey data.« less

  10. Evaluation of Cellular Shades in the PNNL Lab Homes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Petersen, Joseph M.; Sullivan, Greg; Cort, Katherine A.

    This report examines the energy performance of cellular shade window coverings in a matched pair of all-electric, factory-built “Lab Homes” located on the Pacific Northwest National Laboratory (PNNL) campus in Richland, Washington. The 1500-square-foot homes were identical in construction and baseline performance, which allowed any difference in energy and thermal performance between the baseline home and the experimental home to be attributed to the retrofit technology installed in the experimental home. To assess the performance of high efficiency window attachments in a residential retrofit application, the building shell air leakage, energy use, and interior temperatures of each home were comparedmore » during the 2015 -2016 winter heating and summer cooling seasons. Hunter Douglas Duette® Architella® Trielle™ opaque honeycomb “cellular” shades were installed over double-pane clear-glass, aluminum-frame primary windows in the experimental home and were compared to identical primary windows with no window coverings and with standard typical white vinyl horizontal blind window coverings in the baseline home.« less

  11. 75 FR 70935 - Accreditation and Approval of Intertek USA, Inc., as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-19

    ... below for a complete listing of CBP approved gaugers and accredited laboratories. http:[sol][sol]cbp.gov[sol]xp[sol]cgov[sol]import[sol]operations-- support[sol]labs--scientific--svcs[sol]commercial--gaugers[sol]. DATES: The accreditation and approval of Intertek USA, Inc., as commercial gauger and laboratory...

  12. How PNNL Extracts Rare Earth Elements from Geothermal Brine

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2016-07-12

    By looking at a problem at a nanoscale level, PNNL researchers are developing an economic way to extract valuable rare earth elements from geothermal fluids. This novel approach may help meet the high demand for rare earth elements that are used in many clean energy technologies.

  13. Pacific Northwest National Laboratory Annual Site Environmental Report for Calendar Year 2013

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Duncan, Joanne P.; Sackschewsky, Michael R.; Tilden, Harold T.

    2014-09-30

    Pacific Northwest National Laboratory (PNNL), one of the U.S. Department of Energy (DOE) Office of Science’s 10 national laboratories, provides innovative science and technology development in the areas of energy and the environment, fundamental and computational science, and national security. DOE’s Pacific Northwest Site Office (PNSO) is responsible for oversight of PNNL at its Campus in Richland, Washington, as well as its facilities in Sequim, Seattle, and North Bonneville, Washington, and Corvallis and Portland, Oregon.

  14. The Value of Green to the Army

    DTIC Science & Technology

    2011-03-16

    of Management and Budget OSD Office of the Secretary of Defense PBS Public Building Service PEMS Portable Emissions Measurement System PNNL ...Buildings. Pacific Northwest National Laboratory ( PNNL ). July 2008. Eichholtz, Piet, Nils Kok, and John Quigley. Doing well by doing good? An analysis of...M. Jenicek, and Dahtzen Chu March 2011 Approved for public release; distribution is unlimited. ERDC/CERL SR-11-2

  15. 78 FR 16685 - Impax Laboratories, Inc.; Withdrawal of Approval of Bupropion Hydrochloride Extended-Release...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-18

    ...] Impax Laboratories, Inc.; Withdrawal of Approval of Bupropion Hydrochloride Extended-Release Tablets... Administration (FDA) is withdrawing approval of Bupropion Hydrochloride (HCl) Extended-Release Tablets, 300 Milligrams (mg) (Bupropion HCl Extended-Release Tablets 300 mg), under Abbreviated New Drug Application (ANDA...

  16. Economic Impact of Pacific Northwest National Laboratory on the State of Washington in Fiscal Year 2014

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scott, Michael J.; Niemeyer, Jackie M.

    PNNL is a large economic entity with a total of 4,308 employees, $939 million (M) in total funding, and $1.02 billion (B) in total spending during FY 2014. The number of employees that live in Washington State is 4,026 or 93 percent of the Laboratory staff. he Laboratory directly and indirectly supported $1.45 billion in economic output, 6,832 jobs, and $517 million in Washington State wage income from current operations. The state also gained more than $1.19 billion in output, over 6,200 jobs, and $444 million in income through closely related economic activities such as visitors, health care spending, spendingmore » by resident retirees, and spinoff companies. PNNL affects Washington’s economy through commonly recognized economic channels, including spending on payrolls and other goods and services that support Laboratory operations. Less commonly recognized channels also have their own impacts and include company-supported spending on health care for its staff members and retirees, spending of its resident retirees, Laboratory visitor spending, and the economic activities in a growing constellation of “spinoff” companies founded on PNNL research, technology, and managerial expertise. PNNL also has a significant impact on science and technology education and community not-for-profit organizations. PNNL is an active participant in the future scientific enterprise in Washington with the state’s K-12 schools, colleges, and universities. The Laboratory sends staff members to the classroom and brings hundreds of students to the PNNL campus to help train the next generation of scientists, engineers, mathematicians, and technicians. This investment in human capital, though difficult to measure in terms of current dollars of economic output, is among the important lasting legacies of the Laboratory. Finally, PNNL contributes to the local community with millions of dollars’ worth of cash and in-kind corporate and staff contributions, all of which strengthen

  17. PNNL Data-Intensive Computing for a Smarter Energy Grid

    ScienceCinema

    Carol Imhoff; Zhenyu (Henry) Huang; Daniel Chavarria

    2017-12-09

    The Middleware for Data-Intensive Computing (MeDICi) Integration Framework, an integrated platform to solve data analysis and processing needs, supports PNNL research on the U.S. electric power grid. MeDICi is enabling development of visualizations of grid operations and vulnerabilities, with goal of near real-time analysis to aid operators in preventing and mitigating grid failures.

  18. List of Laboratories Approved by EPA for the Fourth Unregulated Contaminant Monitoring Rule (UCMR 4)

    EPA Pesticide Factsheets

    This document provides a list of laboratories that met the Unregulated Contaminant Monitoring Rule 4 (UCMR 4) Laboratory Approval Program application and Proficiency Testing (PT) criteria for the methods indicated.

  19. List of Laboratories Approved by EPA for the Third Unregulated Contaminant Monitoring Rule (UCMR 3)

    EPA Pesticide Factsheets

    This document provides a list of laboratories that met the Unregulated Contaminant Monitoring Rule 3 (UCMR 3) Laboratory Approval Program application and Proficiency Testing (PT) criteria for the methods indicated.

  20. PNNL Strategic Goods Testbed: A Data Library for Illicit Nuclear Trafficking

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Webster, Jennifer B.; Erikson, Luke E.; Toomey, Christopher M.

    2014-05-12

    Pacific Northwest National Laboratory (PNNL) has put significant effort into nonproliferation activities as an institution, both in terms of the classical nuclear material focused approach and in the examination of other strategic goods necessary to implement a nuclear program. To assist in these efforts, several projects in the Analysis in Motion (AIM) and Signature Discovery (SDI) Initiatives at PNNL are developing machine learning methodology for human-computer interaction in real time environments to assist analysts in this domain. All of these technical projects require access to data – whether it is in terms of detector data, shipping records, financial information, companymore » relations, or other communications. The first question that mathematical and computational researchers come up with when asked to build analyst assist or automated tools is “What does the data look like? ” They become frustrated when basic questions like this can not be easily answered and this can have the effect of pushing researchers away from the nuclear trafficking domain, especially in strategic commodity and export control areas where data sets can not easily be generated through standard experimental techniques. For small projects that are building a proof of concept for their methodology, obtaining this data can be arduous and expensive. To relieve the burden of data collection from these projects and grow a lab-wide capability, the Strategic Goods Testbed Team has taken over data collection and placed subscriptions and access to flat data files in a centralized location so that all projects can benefit from these items. We have collected shipping data in the form of PIERS records, judicial information about export control cases, NAC data on the nuclear fuel industry, and financial data from Dun and Bradstreet and our data sets are continuing to expand. With a single access agreement, researchers in data-mining and other fields can utilize all of the records that

  1. 77 FR 34055 - Accreditation and Approval of Saybolt LP, as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-08

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection Accreditation and Approval of Saybolt LP, as a Commercial Gauger and Laboratory AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION: Notice of accreditation and approval of Saybolt LP, as a commercial...

  2. Methods and Models of the Hanford Internal Dosimetry Program, PNNL-MA-860

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carbaugh, Eugene H.; Bihl, Donald E.; Maclellan, Jay A.

    2009-09-30

    The Hanford Internal Dosimetry Program (HIDP) provides internal dosimetry support services for operations at the Hanford Site. The HIDP is staffed and managed by the Radiation and Health Technology group, within the Pacific Northwest National Laboratory (PNNL). Operations supported by the HIDP include research and development, the decontamination and decommissioning of facilities formerly used to produce and purify plutonium, and waste management activities. Radioelements of particular interest are plutonium, uranium, americium, tritium, and the fission and activation product radionuclides 137Cs, 90Sr, and 60Co. This manual describes the technical basis for the design of the routine bioassay monitoring program and formore » assessment of internal dose. The purposes of the manual are as follows: • Provide assurance that the HIDP derives from a sound technical base. • Promote the consistency and continuity of routine program activities. • Provide a historical record. • Serve as a technical reference for radiation protection personnel. • Aid in identifying and planning for future needs.« less

  3. Pacific Northwest National Laboratory Potential Impact Categories for Radiological Air Emission Monitoring

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ballinger, Marcel Y.; Gervais, Todd L.; Barnett, J. Matthew

    2012-06-05

    In 2002, the EPA amended 40 CFR 61 Subpart H and 40 CFR 61 Appendix B Method 114 to include requirements from ANSI/HPS N13.1-1999 Sampling and Monitoring Releases of Airborne Radioactive Substances from the Stack and Ducts of Nuclear Facilities for major emission points. Additionally, the WDOH amended the Washington Administrative Code (WAC) 246-247 Radiation protection-air emissions to include ANSI/HPS N13.1-1999 requirements for major and minor emission points when new permitting actions are approved. A result of the amended regulations is the requirement to prepare a written technical basis for the radiological air emission sampling and monitoring program. A keymore » component of the technical basis is the Potential Impact Category (PIC) assigned to an emission point. This paper discusses the PIC assignments for the Pacific Northwest National Laboratory (PNNL) Integrated Laboratory emission units; this revision includes five PIC categories.« less

  4. 76 FR 80905 - TRICARE Evaluation of Centers for Medicare & Medicaid Services Approved Laboratory Developed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-27

    ... potential high utilization and potential high clinical impact on TRICARE beneficiaries. If no submission is... reviewed in numerical order beginning with the test listed as having the highest priority. Those selected... laboratories that use LDTs as well as FDA approved tests. Laboratories performing moderate or high complexity...

  5. Apel - Applied Process Engineering Laboratory

    Science.gov Websites

    startup and testing Equipment can be quickly connected to building services and effluent systems. A professional, regulated environment for bringing forth new product processes and services. Testing shortens the support Pacific Northwest National Laboratory (PNNL) scientists, engineers, and other professional staff

  6. Fibrin Sealant: The Only Approved Hemostat, Sealant, and Adhesive—a Laboratory and Clinical Perspective

    PubMed Central

    Spotnitz, William D.

    2014-01-01

    Background. Fibrin sealant became the first modern era material approved as a hemostat in the United States in 1998. It is the only agent presently approved as a hemostat, sealant, and adhesive by the Food and Drug Administration (FDA). The product is now supplied as patches in addition to the original liquid formulations. Both laboratory and clinical uses of fibrin sealant continue to grow. The new literature on this material also continues to proliferate rapidly (approximately 200 papers/year). Methods. An overview of current fibrin sealant products and their approved uses and a comprehensive PubMed based review of the recent literature (February 2012, through March 2013) on the laboratory and clinical use of fibrin sealant are provided. Product information is organized into sections based on a classification system for commercially available materials. Publications are presented in sections based on both laboratory research and clinical topics are listed in order of decreasing frequency. Results. Fibrin sealant remains useful hemostat, sealant, and adhesive. New formulations and applications continue to be developed. Conclusions. This agent remains clinically important with the recent introduction of new commercially available products. Fibrin sealant has multiple new uses that should result in further improvements in patient care. PMID:24729902

  7. 77 FR 34054 - Accreditation and Approval of Amspec Services LLC, as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-08

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection Accreditation and Approval of Amspec Services LLC, as a Commercial Gauger and Laboratory AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION: Notice of accreditation and approval of Amspec Services LLC, as a...

  8. 77 FR 50523 - Accreditation and Approval of Amspec Services LLC, as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-21

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection Accreditation and Approval of Amspec Services LLC, as a Commercial Gauger and Laboratory AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION: Notice of accreditation and approval of Amspec Services LLC, as a...

  9. 77 FR 50522 - Accreditation and Approval of Amspec Services LLC, as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-21

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection Accreditation and Approval of Amspec Services LLC, as a Commercial Gauger and Laboratory AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION: Notice of accreditation and approval of Amspec Services LLC, as a...

  10. PNNL Delivers Expertise, Technology to Biofuels Start-up, InEnTec

    ScienceCinema

    Surma, Jeff

    2017-12-09

    Initially through its Entrepreneurial Leave of Absence Program, PNNL gives biofuels innovators a start in opening up a new business based on technology developed for incinerating waste on the Hanford Site. Today, the companies Plasma Enhanced Melters are in operation around the world converting organic waste into valuable, clean fuels.

  11. 75 FR 70935 - Accreditation and Approval of Intertek USA, Inc., as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-19

    ... listed below for a complete listing of CBP approved gaugers and accredited laboratories. http:[sol][sol]cbp.gov[sol]xp[sol]cgov[sol]import[sol]operations-- support[sol]labs--scientific--svcs[sol]commercial--gaugers[sol]. DATES: The accreditation and approval of Intertek USA, Inc., as commercial gauger and...

  12. 75 FR 39550 - Accreditation and Approval of Intertek USA, Inc., as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-09

    ... Intertek USA, Inc., as a Commercial Gauger and Laboratory AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION: Notice of accreditation and approval of Intertek USA, Inc., as a... 151.13, Intertek USA, Inc., 116 Bryan Road Suite 101, Wilmington, NC 28412, has been approved to gauge...

  13. 76 FR 37135 - Accreditation and Approval of Intertek USA, Inc., as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-24

    ... Intertek USA, Inc., as a Commercial Gauger and Laboratory AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION: Notice of accreditation and approval of Intertek USA, Inc., as a... 151.13, Intertek USA, Inc., 4398 Highway 77 N, Marion, AR 72364, has been approved to gauge and...

  14. Customer Satisfaction Survey of Pacific Northwest National Laboratory's Technical Assistance Partners -- FY 2011

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Conger, Robin L.; Spanner, Gary E.

    2011-11-02

    The businesses that have utilized PNNL's Technology Assistance Program were sent a survey to solicit feedback about the program and to determine what, if any, outcomes resulted from the assistance provided. As part of its small business outreach, Pacific Northwest National Laboratory (PNNL) offers technology assistance to businesses with fewer than 500 employees throughout the nation and to businesses of any size in the 2 counties that contain the Hanford site. Upon request, up to 40 staff-hours of a researcher's time can be provided to address technology issues at no charge to the requesting firm. During FY 2011, PNNL completedmore » assistance for 54 firms. Topics of the technology assistance covered a broad range, including environment, energy, industrial processes, medical, materials, computers and software, and sensors. In FY 2011, PNNL's Technology Assistance Program (TAP) was funded by PNNL Overheads. Over the past 16 years, the Technology Assistance Program has received total funding of nearly $2.8 million from several federal and private sources.« less

  15. Radiation Detection Material Discovery Initiative at PNNL

    NASA Astrophysics Data System (ADS)

    Milbrath, Brian

    2006-05-01

    Today's security threats are being met with 30-year old radiation technology. Discovery of new radiation detection materials is currently a slow and Edisonian process. With heightened concerns over nuclear proliferation, terrorism and unconventional warfare, an alternative strategy for identification and development of potential radiation detection materials must be adopted. Through the Radiation Detection Materials Discovery Initiative, PNNL focuses on the science-based discovery of next generation materials for radiation detection by addressing three ``grand challenges'': fundamental understanding of radiation detection, identification of new materials, and accelerating the discovery process. The new initiative has eight projects addressing these challenges, which will be described, including early work, paths forward and the opportunities for collaboration.

  16. Customer Satisfaction Assessment at the Pacific Northwest National Laboratory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Anderson, Dale N.; Sours, Mardell L.

    2000-03-20

    The Pacific Northwest National Laboratory (PNNL) is developing and implementing a customer satisfaction assessment program (CSAP) to assess the quality of research and development provided by the laboratory. We present the customer survey component of the PNNL CSAP. The customer survey questionnaire is composed of 2 major sections, Strategic Value and Project Performance. The Strategic Value section of the questionnaire consists of 5 questions that can be answered with a 5 point Likert scale response. These questions are designed to determine if a project is directly contributing to critical future national needs. The Project Performance section of the questionnaire consistsmore » of 9 questions that can be answered with a 5 point Likert scale response. These questions determine PNNL performance in meeting customer expectations. Many approaches could be used to analyze customer survey data. We present a statistical model that can accurately capture the random behavior of customer survey data. The properties of this statistical model can be used to establish a "gold standard'' or performance expectation for the laboratory, and then assess progress. The gold standard is defined from input from laboratory management --- answers to 4 simple questions, in terms of the information obtained from the CSAP customer survey, define the standard: *What should the average Strategic Value be for the laboratory project portfolio? *What Strategic Value interval should include most of the projects in the laboratory portfolio? *What should average Project Performance be for projects with a Strategic Value of about 2? *What should average Project Performance be for projects with a Strategic Value of about 4? We discuss how to analyze CSAP customer survey data with this model. Our discussion will include "lessons learned" and issues that can invalidate this type of assessment.« less

  17. 9 CFR 54.11 - Approval of laboratories to run official scrapie tests and official genotype tests.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... request approval to conduct one or more types of scrapie test or genotype test on one or more types of... type of test and for each type of tissue for which they request approval. (c) The Administrator may... the laboratory and shall give the director an opportunity to respond. If there are conflicts as to any...

  18. 76 FR 64961 - Accreditation and Approval of SGS North America, Inc. as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-19

    ... of SGS North America, Inc. as a Commercial Gauger and Laboratory AGENCY: Bureau of Customs and Border Protection, Department of Homeland Security. ACTION: Notice of approval of SGS North America, Inc., Carson... 151.12 and 151.13, SGS North America, Inc., Carson, California 90746, has been approved to gauge and...

  19. 77 FR 47427 - Accreditation and Approval of Chem Gas International LLC, as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-08

    ... Chem Gas International LLC, as a Commercial Gauger and Laboratory AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION: Notice of accreditation and approval of Chem Gas... Gas International LLC, as commercial gauger and laboratory became effective on October 19, 2011. The...

  20. Laboratory Directed Research and Development Annual Report for 2009

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hughes, Pamela J.

    This report documents progress made on all LDRD-funded projects during fiscal year 2009. As a US Department of Energy (DOE) Office of Science (SC) national laboratory, Pacific Northwest National Laboratory (PNNL) has an enduring mission to bring molecular and environmental sciences and engineering strengths to bear on DOE missions and national needs. Their vision is to be recognized worldwide and valued nationally for leadership in accelerating the discovery and deployment of solutions to challenges in energy, national security, and the environment. To achieve this mission and vision, they provide distinctive, world-leading science and technology in: (1) the design and scalablemore » synthesis of materials and chemicals; (2) climate change science and emissions management; (3) efficient and secure electricity management from generation to end use; and (4) signature discovery and exploitation for threat detection and reduction. PNNL leadership also extends to operating EMSL: the Environmental Molecular Sciences Laboratory, a national scientific user facility dedicated to providing itnegrated experimental and computational resources for discovery and technological innovation in the environmental molecular sciences.« less

  1. 77 FR 75183 - Accreditation and Approval of Intertek USA, Inc., as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-19

    ... 151.13, Intertek USA, Inc., 2632 Ruby Ave., Gonzales, LA 70737, has been approved to gauge and... 20229, 202-344- 1060. Dated: December 12, 2012. Ira S. Reese, Executive Director, Laboratories and...

  2. 77 FR 14409 - Accreditation and Approval of Intertek USA, Inc., as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-09

    ... 151.13, Intertek USA, Inc., 1145 Fourth Street, Gretna, LA 70053, has been approved to gauge and... 20229, 202-344- 1060. Dated: February 29, 2012. Ira S. Reese, Executive Director, Laboratories and...

  3. PNNL Technical Support to The Implementation of EMTA and EMTA-NLA Models in Autodesk® Moldflow® Packages

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nguyen, Ba Nghiep; Wang, Jin

    2012-12-01

    Under the Predictive Engineering effort, PNNL developed linear and nonlinear property prediction models for long-fiber thermoplastics (LFTs). These models were implemented in PNNL’s EMTA and EMTA-NLA codes. While EMTA is a standalone software for the computation of the composites thermoelastic properties, EMTA-NLA presents a series of nonlinear models implemented in ABAQUS® via user subroutines for structural analyses. In all these models, it is assumed that the fibers are linear elastic while the matrix material can exhibit a linear or typical nonlinear behavior depending on the loading prescribed to the composite. The key idea is to model the constitutive behavior ofmore » the matrix material and then to use an Eshelby-Mori-Tanaka approach (EMTA) combined with numerical techniques for fiber length and orientation distributions to determine the behavior of the as-formed composite. The basic property prediction models of EMTA and EMTA-NLA have been subject for implementation in the Autodesk® Moldflow® software packages. These models are the elastic stiffness model accounting for fiber length and orientation distributions, the fiber/matrix interface debonding model, and the elastic-plastic models. The PNNL elastic-plastic models for LFTs describes the composite nonlinear stress-strain response up to failure by an elastic-plastic formulation associated with either a micromechanical criterion to predict failure or a continuum damage mechanics formulation coupling damage to plasticity. All the models account for fiber length and orientation distributions as well as fiber/matrix debonding that can occur at any stage of loading. In an effort to transfer the technologies developed under the Predictive Engineering project to the American automotive and plastics industries, PNNL has obtained the approval of the DOE Office of Vehicle Technologies to provide Autodesk, Inc. with the technical support for the implementation of the basic property prediction models of EMTA

  4. 77 FR 21792 - Accreditation and Approval of Intertek USA, Inc., as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-11

    ... 151.13, Intertek USA, Inc., 2717 Maplewood Dr., Sulphur, LA 70663, has been approved to gauge and..., Washington, DC 20229, 202-344- 1060. Dated: March 15, 2012. Ira S. Reese, Executive Director, Laboratories...

  5. 76 FR 64962 - Accreditation and Approval of Intertek USA, Inc., as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-19

    ... 151.13, Intertek USA, Inc., 149 Pintail St., St. Rose, LA 70087, has been approved to gauge and...: October 6, 2011. Ira S. Reese, Executive Director, Laboratories and Scientific Services. [FR Doc. 2011...

  6. 77 FR 12866 - Accreditation and Approval of Amspec Services LLC, as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-02

    ... 151.13, Amspec Services LLC, 12154 B River Road, St. Rose, LA 70087, has been approved to gauge and...: February 22, 2012. Ira S. Reese, Executive Director, Laboratories and Scientific Services. [FR Doc. 2012...

  7. 77 FR 75183 - Accreditation and Approval of NMC Global Corporation, as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-19

    ... 151.12 and 19 CFR 151.13, NMC Global Corporation, 326 23rd St., Kenner, LA 70062, has been approved to..., Washington, DC 20229, 202-344- 1060. Dated: December 12, 2012. Ira S. Reese, Executive Director, Laboratories...

  8. Picatinny Arsenal 3000 Area Laboratory Complex Energy Analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brown, Daryl R.; Goddard, James K.

    2010-05-01

    In response to a request by Picatinny Arsenal, the Pacific Northwest National Laboratory (PNNL) was asked by the Army to conduct an energy audit of the Arsenal’s 3000 Area Laboratory Complex. The objective of the audit was to identify life-cycle cost-effective measures that the Arsenal could implement to reduce energy costs. A “walk-through” audit of the facilities was conducted on December 7-8, 2009. Findings and recommendations are included in this document.

  9. Army Installations Water Sustainability Assessment: An Evaluation of Vulnerability to Water Supply

    DTIC Science & Technology

    2009-09-01

    del Norte Water Task Force PM particulate matter PNNL Pacific Northwest National Laboratory PWC Public Works Commission PWD RFTA RSC Regional...ct io n E n gi n ee ri n g R es ea rc h L ab or at or y Approved for public release; distribution is unlimited. ERDC/CERL TR-09-38...and Ryan Holmes University of Illinois at Urbana-Champaign Final Report Approved for public release; distribution is unlimited. Prepared for U.S

  10. 77 FR 75184 - Accreditation and Approval of NMC Global Corporation, as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-19

    ... NMC Global Corporation, as a Commercial Gauger and Laboratory AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION: Notice of accreditation and approval of NMC Global... 151.12 and 19 CFR 151.13, NMC Global Corporation, 1107 Center St., Pasadena, TX 77506, has been...

  11. 75 FR 57478 - Accreditation and Approval of NMC Global Corporation, as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-21

    ... NMC Global Corporation, as a Commercial Gauger and Laboratory AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION: Notice of accreditation and approval of NMC Global... 151.12 and 19 CFR 151.13, NMC Global Corporation, 650 Groves Road Suite 111, Thorofare, NJ 08086, has...

  12. Laboratory Directed Research and Development Annual Report - Fiscal Year 2000

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fisher, Darrell R.; Hughes, Pamela J.; Pearson, Erik W.

    The projects described in this report represent the Laboratory's investment in its future and are vital to maintaining the ability to develop creative solutions for the scientific and technical challenges faced by DOE and the nation. In accordance with DOE guidelines, the report provides, a) a director's statement, b) an overview of the laboratory's LDRD program, including PNNL's management process and a self-assessment of the program, c) a five-year project funding table, and d) project summaries for each LDRD project.

  13. 9 CFR 54.11 - Approval of laboratories to run official scrapie tests and official genotype tests.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Approval of laboratories to run official scrapie tests and official genotype tests. 54.11 Section 54.11 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF...

  14. 9 CFR 55.8 - Official CWD tests and approval of laboratories to conduct official CWD tests.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Official CWD tests and approval of laboratories to conduct official CWD tests. 55.8 Section 55.8 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC...

  15. 9 CFR 55.8 - Official CWD tests and approval of laboratories to conduct official CWD tests.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Official CWD tests and approval of laboratories to conduct official CWD tests. 55.8 Section 55.8 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC...

  16. 9 CFR 55.8 - Official CWD tests and approval of laboratories to conduct official CWD tests.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Official CWD tests and approval of laboratories to conduct official CWD tests. 55.8 Section 55.8 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC...

  17. 9 CFR 55.8 - Official CWD tests and approval of laboratories to conduct official CWD tests.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Official CWD tests and approval of laboratories to conduct official CWD tests. 55.8 Section 55.8 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC...

  18. 9 CFR 54.11 - Approval of laboratories to run official scrapie tests and official genotype tests.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Approval of laboratories to run official scrapie tests and official genotype tests. 54.11 Section 54.11 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF...

  19. 9 CFR 55.8 - Official CWD tests and approval of laboratories to conduct official CWD tests.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Official CWD tests and approval of laboratories to conduct official CWD tests. 55.8 Section 55.8 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC...

  20. 9 CFR 54.11 - Approval of laboratories to run official scrapie tests and official genotype tests.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Approval of laboratories to run official scrapie tests and official genotype tests. 54.11 Section 54.11 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF...

  1. 9 CFR 54.11 - Approval of laboratories to run official scrapie tests and official genotype tests.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Approval of laboratories to run official scrapie tests and official genotype tests. 54.11 Section 54.11 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF...

  2. Collaboratory=Collaborate+Laboratory: The Mid-Columbia STEM Education Collaboratory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Willcuts, Meredith H.; Kennedy, Cathleen A.

    Pacific Northwest National Laboratory created a network focused on collaboration in STEM education to design and deliver projects, resources, and professional learning opportunities in a testbed environment. How do you uncover and fill gaps in equitable access to high-quality science, technology, engineering, and math (STEM) education offerings in your local region? Where might you deploy strategies to improve STEM workforce preparation and increase public understanding of STEM-oriented issues? And how can you help to ensure that students, educators, parents, and the community are aware of these programs and know how to access them in schools, colleges, and community venues? Ifmore » you are the Pacific Northwest National Laboratory (PNNL), you take on the huge goal of designing and implementing an innovative STEM education collaboration project that impacts all levels of local education, both inside and outside of school settings. PNNL is one of the 17 national laboratories funded by the U.S. Department of Energy. Operated by Battelle, PNNL has a vested interest in preparing the next generation of scientists and engineers for their future careers, thus building a STEM-capable workforce and creating a STEM-literate community. One of Battelle’s core principles is a commitment to STEM education and its role in business competitiveness and quality of life. PNNL has been active in STEM education for decades, providing internships for future scientists, giving educators in-house lab experiences, and engaging its researchers in STEM outreach activities in classrooms and the community. The Collaboratory is a relatively recent outcome of Battelle’s longstanding efforts in STEM education. The original Collaboratory planning documents, developed by PNNL’s Office of STEM Education (OSE), state the objective to “design, implement, and mature a local STEM education collaboration zone that highlights the power of PNNL and Battelle to impact the educational ecosystem

  3. PNNL Future Power Grid Initiative-developed GridOPTICS Software System (GOSS)

    ScienceCinema

    None

    2018-01-16

    The power grid is changing and evolving. One aspect of this change is the growing use of smart meters and other devices, which are producing large volumes of useful data. However, in many cases, the data can’t be translated quickly into actionable guidance to improve grid performance. There's a need for innovative tools. The GridOPTICS(TM) Software System, or GOSS, developed through PNNL's Future Power Grid Initiative, is open source and became publicly available in spring 2014. The value of this middleware is that it easily integrates grid applications with sources of data and facilitates communication between them. Such a capability provides a foundation for developing a range of applications to improve grid management.

  4. Task 3: PNNL Visit by JAEA Researchers to Participate in TODAM Code Applications to Fukushima Rivers and to Evaluate the Feasibility of Adaptation of FLESCOT Code to Simulate Radionuclide Transport in the Pacific Ocean Coastal Water Around Fukushima

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Onishi, Yasuo

    Four JAEA researchers visited PNNL for two weeks in February, 2013 to learn the PNNL-developed, unsteady, one-dimensional, river model, TODAM and the PNNL-developed, time-dependent, three dimensional, coastal water model, FLESCOT. These codes predict sediment and contaminant concentrations by accounting sediment-radionuclide interactions, e.g., adsorption/desorption and transport-deposition-resuspension of sediment-sorbed radionuclides. The objective of the river and coastal water modeling is to simulate • 134Cs and 137Cs migration in Fukushima rivers and the coastal water, and • their accumulation in the river and ocean bed along the Fukushima coast. Forecasting the future cesium behavior in the river and coastal water under various scenariosmore » would enable JAEA to assess the effectiveness of various on-land remediation activities and if required, possible river and coastal water clean-up operations to reduce the contamination of the river and coastal water, agricultural products, fish and other aquatic biota. PNNL presented the following during the JAEA visit to PNNL: • TODAM and FLESCOT’s theories and mathematical formulations • TODAM and FLESCOT model structures • Past TODAM and FLESCOT applications • Demonstrating these two codes' capabilities by applying them to simple hypothetical river and coastal water cases. • Initial application of TODAM to the Ukedo River in Fukushima and JAEA researchers' participation in its modeling. PNNL also presented the relevant topics relevant to Fukushima environmental assessment and remediation, including • PNNL molecular modeling and EMSL computer facilities • Cesium adsorption/desorption characteristics • Experiences of connecting molecular science research results to macro model applications to the environment • EMSL tour • Hanford Site road tour. PNNL and JAEA also developed future course of actions for joint research projects on the Fukushima environmental and remediation assessments.« less

  5. Nuclear Proliferation: A Historical Overview

    DTIC Science & Technology

    2008-03-01

    Talbert, “Nuclear Proliferation Technology Trends Analysis ,” Pacific Northwest National Laboratory, PNNL -14480 (September 2005), p. 92. 1973: Closed...L. Coles, and R. J. Talbert, “Nuclear Proliferation Technology Trends Analysis ,” Pacific Northwest National Laboratory, PNNL -14480 (September 2005...D. Zentner, G. L. Coles, and R. J. Talbert, “Nuclear Proliferation Technology Trends Analysis ,” Pacific Northwest National Laboratory, PNNL -14480

  6. PNNL Aviation Biofuels

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Plaza, John; Holladay, John; Hallen, Rich

    2014-10-23

    Commercial airplanes really don’t have the option to move away from liquid fuels. Because of this, biofuels present an opportunity to create new clean energy jobs by developing technologies that deliver stable, long term fuel options. The Department of Energy’s Pacific Northwest National Laboratory is working with industrial partners on processes to convert biomass to aviation fuels.

  7. 46 CFR 160.017-7 - Independent laboratory.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Independent laboratory. 160.017-7 Section 160.017-7...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Chain Ladder § 160.017-7 Independent laboratory. The approval... laboratory accepted by the Coast Guard under subpart 159.010 of this chapter. ...

  8. 46 CFR 160.017-7 - Independent laboratory.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Independent laboratory. 160.017-7 Section 160.017-7...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Chain Ladder § 160.017-7 Independent laboratory. The approval... laboratory accepted by the Coast Guard under subpart 159.010 of this chapter. ...

  9. PNNL Aviation Biofuels

    ScienceCinema

    Plaza, John; Holladay, John; Hallen, Rich

    2018-06-06

    Commercial airplanes really don’t have the option to move away from liquid fuels. Because of this, biofuels present an opportunity to create new clean energy jobs by developing technologies that deliver stable, long term fuel options. The Department of Energy’s Pacific Northwest National Laboratory is working with industrial partners on processes to convert biomass to aviation fuels.

  10. 46 CFR 160.171-5 - Independent laboratory.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Independent laboratory. 160.171-5 Section 160.171-5...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Immersion Suits § 160.171-5 Independent laboratory. The approval and production tests in this subpart must be conducted by an independent laboratory accepted by the...

  11. 46 CFR 163.003-7 - Independent laboratory.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Independent laboratory. 163.003-7 Section 163.003-7...: SPECIFICATIONS AND APPROVAL CONSTRUCTION Pilot Ladder § 163.003-7 Independent laboratory. The approval and production tests in this subpart must be conducted by or under the supervision of an independent laboratory...

  12. 46 CFR 160.171-5 - Independent laboratory.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Independent laboratory. 160.171-5 Section 160.171-5...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Immersion Suits § 160.171-5 Independent laboratory. The approval and production tests in this subpart must be conducted by an independent laboratory accepted by the...

  13. 46 CFR 163.003-7 - Independent laboratory.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Independent laboratory. 163.003-7 Section 163.003-7...: SPECIFICATIONS AND APPROVAL CONSTRUCTION Pilot Ladder § 163.003-7 Independent laboratory. The approval and production tests in this subpart must be conducted by or under the supervision of an independent laboratory...

  14. 46 CFR 163.002-7 - Independent laboratory.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Independent laboratory. 163.002-7 Section 163.002-7...: SPECIFICATIONS AND APPROVAL CONSTRUCTION Pilot Hoist § 163.002-7 Independent laboratory. (a) The approval and production tests in this subpart must be conducted by, or under the supervision of, an independent laboratory...

  15. 46 CFR 163.002-7 - Independent laboratory.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Independent laboratory. 163.002-7 Section 163.002-7...: SPECIFICATIONS AND APPROVAL CONSTRUCTION Pilot Hoist § 163.002-7 Independent laboratory. (a) The approval and production tests in this subpart must be conducted by, or under the supervision of, an independent laboratory...

  16. Undergraduate Chemistry Laboratory

    ERIC Educational Resources Information Center

    Bretz, Stacey Lowery; Fay, Michael; Bruck, Laura B.; Towns, Marcy H.

    2013-01-01

    Forty chemistry faculty from American Chemical Society-approved departments were interviewed to determine their goals for undergraduate chemistry laboratory. Faculty were stratified by type of institution, departmental success with regard to National Science Foundation funding for laboratory reform, and level of laboratory course. Interview…

  17. Commercial Building Partners Catalyze Energy Efficient Buildings Across the Nation

    DTIC Science & Technology

    2012-08-01

    PNNL ) with companies starting in 2008 and discusses some partner insights from projects joining the program later. In 2008, PNNL and the National...provides an overview of the CBP effort and the variety of buildings and partners currently participating with PNNL . Many of the projects are now...Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the collection of information is estimated to average 1 hour per response

  18. Phillips Laboratory Geophysics Scholar Program

    DTIC Science & Technology

    1993-09-30

    research at Phillips Laboratory . Research sponsored by Air Force Geophysics Laboratory ...Geophysics Laboratory (now the Phillips Laboratory , Geophysics Directorate), United States Air Force for its sponsorship of this research through the Air ...September 1993 Approved for public release; distribution unlimited PHILLIPS LABORATORY Directorate of Geophysics AIR FORCE MATERIEL COMMAND

  19. Radiation and Health Technology Laboratory Capabilities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bihl, Donald E.; Lynch, Timothy P.; Murphy, Mark K.

    2005-07-09

    The Radiological Standards and Calibrations Laboratory, a part of Pacific Northwest National Laboratory (PNNL)(a) performs calibrations and upholds reference standards necessary to maintain traceability to national standards. The facility supports U.S. Department of Energy (DOE) programs at the Hanford Site, programs sponsored by DOE Headquarters and other federal agencies, radiological protection programs at other DOE and commercial nuclear sites and research and characterization programs sponsored through the commercial sector. The laboratory is located in the 318 Building of the Hanford Site's 300 Area. The facility contains five major exposure rooms and several laboratories used for exposure work preparation, low-activity instrumentmore » calibrations, instrument performance evaluations, instrument maintenance, instrument design and fabrication work, thermoluminescent and radiochromic Dosimetry, and calibration of measurement and test equipment (M&TE). The major exposure facilities are a low-scatter room used for neutron and photon exposures, a source well room used for high-volume instrument calibration work, an x-ray facility used for energy response studies, a high-exposure facility used for high-rate photon calibration work, a beta standards laboratory used for beta energy response studies and beta reference calibrations and M&TE laboratories. Calibrations are routinely performed for personnel dosimeters, health physics instrumentation, photon and neutron transfer standards alpha, beta, and gamma field sources used throughout the Hanford Site, and a wide variety of M&TE. This report describes the standards and calibrations laboratory.« less

  20. Physical Property Analysis and Report for Sediments at 100-BC-5 Operable Unit, Boreholes C7505, C7506, C7507, and C7665

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lindberg, Michael J.

    2010-09-28

    Between October 14, 2009 and February 22, 2010 sediment samples were received from 100-BC Decision Unit for geochemical studies. This is an analytical data report for sediments received from CHPRC at the 100 BC 5 OU. The analyses for this project were performed at the 325 building located in the 300 Area of the Hanford Site. The analyses were performed according to Pacific Northwest National Laboratory (PNNL) approved procedures and/or nationally recognized test procedures. The data sets include the sample identification numbers, analytical results, estimated quantification limits (EQL), and quality control data. The preparatory and analytical quality control requirements, calibrationmore » requirements, acceptance criteria, and failure actions are defined in the on-line QA plan 'Conducting Analytical Work in Support of Regulatory Programs' (CAW). This QA plan implements the Hanford Analytical Services Quality Assurance Requirements Documents (HASQARD) for PNNL.« less

  1. 46 CFR 162.017-6 - Procedure for approval.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... screens. (c) Pre-approval tests. Before approval is granted, the manufacturer shall have tests conducted, or submit evidence that such tests have been conducted, by the Underwriters' Laboratories, the... design or type of pressure-vacuum relief valve shall submit drawings in quadruplicate showing the design...

  2. 46 CFR 162.017-6 - Procedure for approval.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... screens. (c) Pre-approval tests. Before approval is granted, the manufacturer shall have tests conducted, or submit evidence that such tests have been conducted, by the Underwriters' Laboratories, the... design or type of pressure-vacuum relief valve shall submit drawings in quadruplicate showing the design...

  3. Valid methods: the quality assurance of test method development, validation, approval, and transfer for veterinary testing laboratories.

    PubMed

    Wiegers, Ann L

    2003-07-01

    Third-party accreditation is a valuable tool to demonstrate a laboratory's competence to conduct testing. Accreditation, internationally and in the United States, has been discussed previously. However, accreditation is only I part of establishing data credibility. A validated test method is the first component of a valid measurement system. Validation is defined as confirmation by examination and the provision of objective evidence that the particular requirements for a specific intended use are fulfilled. The international and national standard ISO/IEC 17025 recognizes the importance of validated methods and requires that laboratory-developed methods or methods adopted by the laboratory be appropriate for the intended use. Validated methods are therefore required and their use agreed to by the client (i.e., end users of the test results such as veterinarians, animal health programs, and owners). ISO/IEC 17025 also requires that the introduction of methods developed by the laboratory for its own use be a planned activity conducted by qualified personnel with adequate resources. This article discusses considerations and recommendations for the conduct of veterinary diagnostic test method development, validation, evaluation, approval, and transfer to the user laboratory in the ISO/IEC 17025 environment. These recommendations are based on those of nationally and internationally accepted standards and guidelines, as well as those of reputable and experienced technical bodies. They are also based on the author's experience in the evaluation of method development and transfer projects, validation data, and the implementation of quality management systems in the area of method development.

  4. 9 CFR 130.11 - User fees for inspecting and approving import/export facilities and establishments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... hourly user fee rate in § 130.30(2) applies to biosecurity level two laboratories. (b) [Reserved] [65 FR... approval) Per year $537.00 $553.00 $570.00 $587.00 $604.00 Inspection for approval of biosecurity level three labs (all inspections related to approving the laboratory for handling one defined set of...

  5. STP K Basin Sludge Sample Archive at the Pacific Northwest National Laboratory FY2014

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fiskum, Sandra K.; Smoot, Margaret R.; Schmidt, Andrew J.

    2014-06-01

    The Pacific Northwest National Laboratory (PNNL) currently houses 88 samples (~10.5 kg) of K Basin sludge (81 wet and seven dry samples) on behalf of the Sludge Treatment Project (STP), which is managed for the U.S. Department of Energy (DOE) by the CH2M Hill Plateau Remediation Company (CHPRC). Selected samples are intended to serve, in part, as sentinels to enhance understanding of sludge properties after long-term storage, and thus enhance understanding of sludge behavior following transfer to sludge transfer and storage containers (STSCs) and storage at the Hanford 200 Area central plateau. In addition, remaining samples serve in contingency formore » future testing requirements. At PNNL, the samples are tracked and maintained under a prescriptive and disciplined monthly sample-monitoring program implemented by PNNL staff. This report updates the status of the K Basin archive sludge sample inventory to April 2014. The previous inventory status report, PNNL 22245 (Fiskum et al. 2013, limited distribution report), was issued in February of 2013. This update incorporates changes in the inventory related to repackaging of 17 samples under test instructions 52578 TI052, K Basin Sludge Sample Repackaging for Continued Long Term Storage, and 52578 TI053, K Basin Sludge Sample Repackaging Post-2014 Shear Strength Measurements. Note that shear strength measurement results acquired in 2014 are provided separately. Specifically, this report provides the following: • a description of the K Basin sludge sample archive program and the sample inventory • a summary and images of the samples that were repackaged in April 2014 • up-to-date images and plots of the settled density and water loss from all applicable samples in the inventory • updated sample pedigree charts, which provide a roadmap of the genesis and processing history of each sample in the inventory • occurrence and deficiency reports associated with sample storage and repackaging« less

  6. 7 CFR 802.1 - Qualified laboratories.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 7 2011-01-01 2011-01-01 false Qualified laboratories. 802.1 Section 802.1... REQUIREMENTS FOR GRAIN WEIGHING EQUIPMENT AND RELATED GRAIN HANDLING SYSTEMS § 802.1 Qualified laboratories. (a) Metrology laboratories. (1) Any State metrology laboratory currently approved by the NBS ongoing...

  7. Venetoclax: First Global Approval.

    PubMed

    Deeks, Emma D

    2016-06-01

    Venetoclax (Venclexta™) is an oral selective inhibitor of the prosurvival protein BCL-2 and therefore restores the apoptotic ability of malignant cells. The drug arose from research by Abbott Laboratories (now AbbVie) during a collaboration with Genentech and is being co-developed by AbbVie and Genentech/Roche primarily for the treatment of haematological malignancies. Venetoclax is approved in the USA for use as monotherapy in patients with chronic lymphocytic leukaemia (CLL) with the 17p deletion (as detected by an approved FDA test) who have received at least one prior therapy, and is awaiting approval for similar indications in the EU and Canada. Venetoclax is also in phase I-III development as combination therapy for CLL, phase I/II development as monotherapy and/or combination therapy for non-Hodgkin lymphomas (including diffuse large B-cell lymphoma, mantle cell lymphoma, follicular lymphoma) and acute myeloid leukaemia, and phase I development for multiple myeloma, systemic lupus erythematosus and breast cancer. This article summarizes the milestones in the development of venetoclax leading to this first approval for CLL.

  8. 7 CFR 983.1 - Accredited laboratory.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Accredited laboratory. 983.1 Section 983.1 Agriculture..., ARIZONA, AND NEW MEXICO Definitions § 983.1 Accredited laboratory. An accredited laboratory is a laboratory that has been approved or accredited by the U.S. Department of Agriculture. [74 FR 56539, Nov. 2...

  9. Economic Analysis of Alternatives for PC Upgrade of OR Department Laboratory

    DTIC Science & Technology

    1990-09-01

    DEPARTMENT LABORATORY by Chen Lung-Shan September, 1990 Thesis Advisor: Thomas E. Halwachs Approved for public release; distribution is unlimited. 91...b. RESTRICTIVE MARKINGS UNCLASSIFIED 2a. SECURITY CLASSIFICATION AUTHORITY 3. DISTRIBUTION/AVAILABILITY OF REPORT Approved for public release...Approved for public release; distribution is unlimited. Economic Analysis Of Alternatives For PC Upgrade Of OR Department Laboratory by Lung-shan Chen

  10. Amprenavir, new protease inhibitor, approved.

    PubMed

    James, J S

    1999-05-07

    A new protease inhibitor, amprenavir (Agenerase), has received FDA marketing approval. The approval was based on two 24-week controlled trials and safety data in more than 1,400 patients under FDA accelerated-approval rules. Amprenavir is approved for patients 4 years of age and older. The drug is taken twice daily, with or without food. Side effects include gastrointestinal disturbances, rashes, and oral paresthesia. Severe or life-threatening rashes have occurred in 1 percent of all patients. Pregnant women should not use the drug unless necessary. The drug was developed by Vertex Pharmaceuticals Inc. and is being marketed by Glaxo Wellcome. Some studies suggest that amprenavir is less likely than other protease inhibitors to be associated with lipid metabolism problems. It may have a resistance profile different from that of other protease inhibitors, and therefore may cause different cross resistance problems. Amprenavir appears to be synergistic with abacavir (Ziagen) in laboratory tests.

  11. MICROBIAL LABORATORY GUIDANCE MANUAL FOR THE ...

    EPA Pesticide Factsheets

    The Long-Term 2 Enhanced Surface Water Treatment Rule Laboratory Instruction Manual will be a compilation of all information needed by laboratories and field personnel to collect, analyze, and report the microbiological data required under the rule. The manual will provide laboratories with a single source of information that currently is available from various sources including the latest versions of Methods 1622 and 1623, including all approved, equivalent modifications; the procedures for E.coli methods approved for use under the LT2ESWTR; lists of vendor sources; data recording forms; data reporting requirements; information on the Laboratory Quality Assurance Evaluation Program for the Analysis of Cryptosporidium in Water; and sample collection procedures. Although most of this information is available elsewhere, a single, comprehensive compendium containing this information is needed to aid utilities and laboratories performing the sampling and analysis activities required under the LT2 rule. This manual will serve as an instruction manual for laboratories to use when collecting data for Crypto, E. coli and turbidity.

  12. 2015 Fermilab Laboratory Directed Research & Development Annual Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wester, W.

    2016-05-26

    The Fermi National Accelerator Laboratory (FNAL) is conducting a Laboratory Directed Research and Development (LDRD) program. Fiscal year 2015 represents the first full year of LDRD at Fermilab and includes seven projects approved mid-year in FY14 and six projects approved in FY15. One of the seven original projects has been completed just after the beginning of FY15. The implementation of LDRD at Fermilab is captured in the approved Fermilab 2015 LDRD Annual Program Plan. In FY15, the LDRD program represents 0.64% of Laboratory funding. The scope of the LDRD program at Fermilab will be established over the next couple ofmore » years where a portfolio of about 20 on-going projects representing approximately between 1% and 1.5% of the Laboratory funding is anticipated. This Annual Report focuses on the status of the current projects and provides an overview of the current status of LDRD at Fermilab.« less

  13. 7 CFR 3300.55 - Termination of approval.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... BE USED FOR SUCH CARRIAGE (ATP); INSPECTION, TESTING, AND CERTIFICATION OF SPECIAL EQUIPMENT Approval... incapable of performing tests according to the standards in the ATP, or noncompliance of the laboratory with...

  14. 7 CFR 3300.55 - Termination of approval.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... BE USED FOR SUCH CARRIAGE (ATP); INSPECTION, TESTING, AND CERTIFICATION OF SPECIAL EQUIPMENT Approval... incapable of performing tests according to the standards in the ATP, or noncompliance of the laboratory with...

  15. 7 CFR 3300.55 - Termination of approval.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... BE USED FOR SUCH CARRIAGE (ATP); INSPECTION, TESTING, AND CERTIFICATION OF SPECIAL EQUIPMENT Approval... incapable of performing tests according to the standards in the ATP, or noncompliance of the laboratory with...

  16. 7 CFR 3300.55 - Termination of approval.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... BE USED FOR SUCH CARRIAGE (ATP); INSPECTION, TESTING, AND CERTIFICATION OF SPECIAL EQUIPMENT Approval... incapable of performing tests according to the standards in the ATP, or noncompliance of the laboratory with...

  17. 7 CFR 3300.55 - Termination of approval.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... BE USED FOR SUCH CARRIAGE (ATP); INSPECTION, TESTING, AND CERTIFICATION OF SPECIAL EQUIPMENT Approval... incapable of performing tests according to the standards in the ATP, or noncompliance of the laboratory with...

  18. 46 CFR 160.077-9 - Recognized laboratory.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Recognized laboratory. 160.077-9 Section 160.077-9... Recognized laboratory. (a) A manufacturer seeking Coast Guard approval of a product under this subpart shall... to a recognized independent laboratory. The following laboratories are recognized under § 159.010-7...

  19. 46 CFR 164.019-17 - Recognized laboratory.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Recognized laboratory. 164.019-17 Section 164.019-17...: SPECIFICATIONS AND APPROVAL MATERIALS Personal Flotation Device Components § 164.019-17 Recognized laboratory. (a) General. A laboratory may be designated as a recognized laboratory under this subpart if it is— (1...

  20. 46 CFR 160.048-8 - Recognized laboratory.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Recognized laboratory. 160.048-8 Section 160.048-8... Recognized laboratory. (a) A manufacturer seeking Coast Guard approval of a product under this subpart shall... to a recognized independent laboratory. The following laboratories are recognized under § 159.010-7...

  1. 46 CFR 160.048-8 - Recognized laboratory.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Recognized laboratory. 160.048-8 Section 160.048-8... Recognized laboratory. (a) A manufacturer seeking Coast Guard approval of a product under this subpart shall... to a recognized independent laboratory. The following laboratories are recognized under § 159.010-7...

  2. 46 CFR 164.019-17 - Recognized laboratory.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Recognized laboratory. 164.019-17 Section 164.019-17...: SPECIFICATIONS AND APPROVAL MATERIALS Personal Flotation Device Components § 164.019-17 Recognized laboratory. (a) General. A laboratory may be designated as a recognized laboratory under this subpart if it is— (1...

  3. 46 CFR 160.077-9 - Recognized laboratory.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Recognized laboratory. 160.077-9 Section 160.077-9... Recognized laboratory. (a) A manufacturer seeking Coast Guard approval of a product under this subpart shall... to a recognized independent laboratory. The following laboratories are recognized under § 159.010-7...

  4. 75 FR 3245 - Accreditation and Approval of King Laboratories, Inc., as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-20

    ... King Laboratories, Inc., as a Commercial Gauger and Laboratory AGENCY: U.S. Customs and Border... Laboratories, Inc., as a commercial gauger and laboratory. SUMMARY: Notice is hereby given that, pursuant to 19 CFR 151.12 and 19 CFR 151.13, King Laboratories, Inc., 1300 E. 223rd St., 401, Carson, CA 90745, has...

  5. 75 FR 57478 - Accreditation and Approval of King Laboratories, Inc., as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-21

    ... King Laboratories, Inc., as a Commercial Gauger and Laboratory AGENCY: U.S. Customs and Border... Laboratories, Inc., as a commercial gauger and laboratory. SUMMARY: Notice is hereby given that, pursuant to 19 CFR 151.12 and 19 CFR 151.13, King Laboratories, Inc., 5009 S. MacDill Ave., Tampa, FL 33611, has been...

  6. Summary of the Graduate Mentoring Assistance Program for PNNL PNNL.12.006 (April 2012 – May 31, 2013)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schwantes, Jon M.

    2013-05-01

    multivariate data analysis to detect anomalies in operation. Last year, Mr. Dayman investigated methods to classify spent nuclear fuel according to both reactor type and burn up based on the constituent nuclide activities, which may be used to more accurately calibrate other models in an analysis scheme in order to improve the accuracy and precision of predictions. He is currently writing up his results for publication and has transitioned to another project with Dr. Derrick Haas at PNNL.« less

  7. 46 CFR 160.064-7 - Recognized laboratory.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Recognized laboratory. 160.064-7 Section 160.064-7...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Marine Buoyant Devices § 160.064-7 Recognized laboratory. (a) A... laboratory. The following laboratories are recognized under § 159.010-7 of this part, to perform testing and...

  8. 46 CFR 160.064-7 - Recognized laboratory.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Recognized laboratory. 160.064-7 Section 160.064-7...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Marine Buoyant Devices § 160.064-7 Recognized laboratory. (a) A... laboratory. The following laboratories are recognized under § 159.010-7 of this part, to perform testing and...

  9. DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    Case study describes Pacific Northwest National Laboratory's (PNNL) three-month Rock the Watt campaign to reduce energy use at its main campus in Richland, Washington. The campaign objectives were to educate PNNL employees about energy conservation opportunities in their workplace and to motivate them to help PNNL save energy and costs and to reduce greenhouse gas emissions.

  10. Marine Sciences Laboratory Radionuclide Air Emissions Report for Calendar Year 2013

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Snyder, Sandra F.; Barnett, J. Matthew; Ballinger, Marcel Y.

    2014-05-01

    The U.S. Department of Energy Office of Science (DOE-SC) Pacific Northwest Site Office (PNSO) has oversight and stewardship duties associated with the Pacific Northwest National Laboratory (PNNL) Marine Sciences Laboratory (MSL) located on Battelle Land – Sequim (Sequim). This report is prepared to document compliance with the Code of Federal Regulations (CFR), Title 40, Protection of the Environment, Part 61, National Emission Standards for Hazardous Air Pollutants (NESHAP), Subpart H, “National Emission Standards for Emissions of Radionuclides Other than Radon from Department of Energy Facilities” and Washington Administrative Code (WAC) Chapter 246-247, “Radiation Protection–Air Emissions.” The EDE to the Sequimmore » MEI due to routine operations in 2013 was 5E-05 mrem (5E-07 mSv). No non-routine emissions occurred in 2013. The MSL is in compliance with the federal and state 10 mrem/yr standard.« less

  11. Marine Sciences Laboratory Radionuclide Air Emissions Report for Calendar Year 2014

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Snyder, Sandra F.; Barnett, J. Matthew

    2015-05-04

    The U.S. Department of Energy Office of Science (DOE-SC) Pacific Northwest Site Office (PNSO) has oversight and stewardship duties associated with the Pacific Northwest National Laboratory (PNNL) Marine Sciences Laboratory (MSL) located on Battelle Land – Sequim.This report is prepared to document compliance with the Code of Federal Regulations (CFR), Title 40, Protection of the Environment, Part 61, National Emission Standards for Hazardous Air Pollutants (NESHAP), Subpart H, ''National Emission Standards for Emissions of Radionuclides Other than Radon from Department of Energy Facilities” and Washington Administrative Code (WAC) Chapter 246-247, “Radiation Protection–Air Emissions.'' The EDE to the MSL MEI duemore » to routine operations in 2014 was 9E-05 mrem (9E-07 mSv). No non-routine emissions occurred in 2014. The MSL is in compliance with the federal and state 10 mrem/yr standard.« less

  12. 46 CFR 160.176-7 - Independent laboratories.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Independent laboratories. 160.176-7 Section 160.176-7...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Inflatable Lifejackets § 160.176-7 Independent laboratories. A list of independent laboratories which have been accepted by the Commandant for conducting or...

  13. 46 CFR 160.176-7 - Independent laboratories.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Independent laboratories. 160.176-7 Section 160.176-7...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Inflatable Lifejackets § 160.176-7 Independent laboratories. A list of independent laboratories which have been accepted by the Commandant for conducting or...

  14. 46 CFR 160.151-9 - Independent laboratory.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Independent laboratory. 160.151-9 Section 160.151-9...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Inflatable Liferafts (SOLAS) § 160.151-9 Independent laboratory. Tests and inspections that this subpart requires to be conducted by an independent laboratory must be...

  15. 46 CFR 160.174-5 - Independent laboratory.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Independent laboratory. 160.174-5 Section 160.174-5...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Thermal Protective Aids § 160.174-5 Independent laboratory. (a... laboratory accepted by the Coast Guard under subpart 159.010 of this chapter. (b) [Reserved] ...

  16. 46 CFR 160.151-9 - Independent laboratory.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Independent laboratory. 160.151-9 Section 160.151-9...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Inflatable Liferafts (SOLAS) § 160.151-9 Independent laboratory. Tests and inspections that this subpart requires to be conducted by an independent laboratory must be...

  17. 46 CFR 160.174-5 - Independent laboratory.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Independent laboratory. 160.174-5 Section 160.174-5...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Thermal Protective Aids § 160.174-5 Independent laboratory. (a... laboratory accepted by the Coast Guard under subpart 159.010 of this chapter. (b) [Reserved] ...

  18. 42 CFR 493.551 - General requirements for laboratories.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 5 2011-10-01 2011-10-01 false General requirements for laboratories. 493.551... SERVICES (CONTINUED) STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS Accreditation by a Private, Nonprofit Accreditation Organization or Exemption Under an Approved State Laboratory Program § 493.551...

  19. 42 CFR 493.551 - General requirements for laboratories.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false General requirements for laboratories. 493.551... SERVICES (CONTINUED) STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS Accreditation by a Private, Nonprofit Accreditation Organization or Exemption Under an Approved State Laboratory Program § 493.551...

  20. 46 CFR 164.012-12 - Recognized laboratory.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Recognized laboratory. 164.012-12 Section 164.012-12...: SPECIFICATIONS AND APPROVAL MATERIALS Interior Finishes for Merchant Vessels § 164.012-12 Recognized laboratory. A recognized laboratory is one which is operated as a nonprofit public service and is regularly...

  1. 46 CFR 164.012-12 - Recognized laboratory.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Recognized laboratory. 164.012-12 Section 164.012-12...: SPECIFICATIONS AND APPROVAL MATERIALS Interior Finishes for Merchant Vessels § 164.012-12 Recognized laboratory. A recognized laboratory is one which is operated as a nonprofit public service and is regularly...

  2. 46 CFR 160.010-10 - Independent laboratory.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Independent laboratory. 160.010-10 Section 160.010-10... laboratory. (a) The approval and production tests in this subpart must be conducted by an independent laboratory accepted by the Coast Guard under subpart 159.010 of this chapter. (b) [Reserved] ...

  3. 46 CFR 160.010-10 - Independent laboratory.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Independent laboratory. 160.010-10 Section 160.010-10... laboratory. (a) The approval and production tests in this subpart must be conducted by an independent laboratory accepted by the Coast Guard under subpart 159.010 of this chapter. (b) [Reserved] ...

  4. Ultraviolet light-an FDA approved technology

    USDA-ARS?s Scientific Manuscript database

    Ultraviolet Light (254 nm) is a U.S. Food and Drug Administration approved nonthermal intervention technology that can be used for decontamination of food and food contact surfaces. Ultraviolet light is a green technology that leaves no chemical residues. Results from our laboratory indicate that ex...

  5. 46 CFR 164.009-21 - Laboratory report.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Laboratory report. 164.009-21 Section 164.009-21 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL MATERIALS Noncombustible Materials for Merchant Vessels § 164.009-21 Laboratory report. The laboratory report of the test...

  6. 46 CFR 164.009-21 - Laboratory report.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 6 2013-10-01 2013-10-01 false Laboratory report. 164.009-21 Section 164.009-21 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL MATERIALS Noncombustible Materials for Merchant Vessels § 164.009-21 Laboratory report. The laboratory report of the test...

  7. 46 CFR 164.009-21 - Laboratory report.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 6 2014-10-01 2014-10-01 false Laboratory report. 164.009-21 Section 164.009-21 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL MATERIALS Noncombustible Materials for Merchant Vessels § 164.009-21 Laboratory report. The laboratory report of the test...

  8. 46 CFR 164.009-21 - Laboratory report.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 6 2012-10-01 2012-10-01 false Laboratory report. 164.009-21 Section 164.009-21 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL MATERIALS Noncombustible Materials for Merchant Vessels § 164.009-21 Laboratory report. The laboratory report of the test...

  9. Laboratory Testing of Bulk Vitrified Low-Activity Waste Forms to Support the 2005 Integrated Disposal Facility Performance Assessment. Erratum

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smith, Gary L.

    2016-09-06

    This report refers to or contains K g values for glasses LAWA44, LAWB45 and LAWC22 affected by calculations errors as identified by Papathanassiu et al. (2011). The corrected K g values are reported in an erratum included in the revised version of the original report. The revised report can be referenced as follows: Pierce E. M. et al. (2004) Waste Form Release Data Package for the 2005 Integrated Disposal Facility Performance Assessment. PNNL-14805 Rev. 0 Erratum. Pacific Northwest National Laboratory, Richland, WA, USA.

  10. Evaluation of Cumulative Ecosystem Response to Restoration Projects in the Lower Columbia River and Estuary, 2010

    DTIC Science & Technology

    2012-05-01

    and PNNL , with funding from the U.S. Environ- mental Protection Agency, are developing a GIS platform with layers for a habitat change analysis , a... PNNL -20296 Prepared for the U.S. Army Corps of Engineers, Portland District Under an Interagency Agreement with the U.S. Department of Energy...University of Washington May 2012 Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the collection of information is

  11. 30 CFR 6.10 - Use of independent laboratories.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Use of independent laboratories. 6.10 Section 6..., AND APPROVAL OF MINING PRODUCTS TESTING AND EVALUATION BY INDEPENDENT LABORATORIES AND NON-MSHA PRODUCT SAFETY STANDARDS § 6.10 Use of independent laboratories. (a) MSHA will accept testing and...

  12. 46 CFR 160.026-7 - Procedure for approval.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... lifeboats and liferafts on merchant vessels is approved only by the Commandant, U.S. Coast Guard. (b) Pre... required tests in accordance with § 160.026-5 performed by an independent laboratory accepted by the Coast...

  13. Comprehensive Energy and Water Master Plan, Redstone Arsenal

    DTIC Science & Technology

    2009-01-01

    Facility Energy Decision System (FEDS) analysis completed by the Pacific Northwest National Laboratory ( PNNL ). This model presents a clear picture of...steam options analysis conducted by Pacific Northwest National Laboratory ( PNNL ) giving priority to strategies that maximize the use of waste for...0704-0188 Public reporting burden for the collection of information is estimated to average 1 hour per response, including the time for reviewing

  14. 42 CFR 493.555 - Federal review of laboratory requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 5 2011-10-01 2011-10-01 false Federal review of laboratory requirements. 493.555... SERVICES (CONTINUED) STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS Accreditation by a Private, Nonprofit Accreditation Organization or Exemption Under an Approved State Laboratory Program § 493.555...

  15. 42 CFR 493.555 - Federal review of laboratory requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Federal review of laboratory requirements. 493.555... SERVICES (CONTINUED) STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS Accreditation by a Private, Nonprofit Accreditation Organization or Exemption Under an Approved State Laboratory Program § 493.555...

  16. Lamprey Tagging

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Colotelo, Alison; Deters, Kate

    2017-05-26

    Pacific Northwest National Laboratory has developed a super-small acoustic tracking tag designed just for juvenile lamprey. In this video, PNNL researcher Alison Colotelo describes how she and her colleague Kate Deters inject young lamprey with the PNNL tag.

  17. [Accreditation of medical laboratories].

    PubMed

    Horváth, Andrea Rita; Ring, Rózsa; Fehér, Miklós; Mikó, Tivadar

    2003-07-27

    In Hungary, the National Accreditation Body was established by government in 1995 as an independent, non-profit organization, and has exclusive rights to accredit, amongst others, medical laboratories. The National Accreditation Body has two Specialist Advisory Committees in the health care sector. One is the Health Care Specialist Advisory Committee that accredits certifying bodies, which deal with certification of hospitals. The other Specialist Advisory Committee for Medical Laboratories is directly involved in accrediting medical laboratory services of health care institutions. The Specialist Advisory Committee for Medical Laboratories is a multidisciplinary peer review group of experts from all disciplines of in vitro diagnostics, i.e. laboratory medicine, microbiology, histopathology and blood banking. At present, the only published International Standard applicable to laboratories is ISO/IEC 17025:1999. Work has been in progress on the official approval of the new ISO 15189 standard, specific to medical laboratories. Until the official approval of the International Standard ISO 15189, as accreditation standard, the Hungarian National Accreditation Body has decided to progress with accreditation by formulating explanatory notes to the ISO/IEC 17025:1999 document, using ISO/FDIS 15189:2000, the European EC4 criteria and CPA (UK) Ltd accreditation standards as guidelines. This harmonized guideline provides 'explanations' that facilitate the application of ISO/IEC 17025:1999 to medical laboratories, and can be used as a checklist for the verification of compliance during the onsite assessment of the laboratory. The harmonized guideline adapted the process model of ISO 9001:2000 to rearrange the main clauses of ISO/IEC 17025:1999. This rearrangement does not only make the guideline compliant with ISO 9001:2000 but also improves understanding for those working in medical laboratories, and facilitates the training and education of laboratory staff. With the

  18. Initial characterization of unequal-length, low-background proportional counters for absolute gas-counting applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mace, E. K.; Aalseth, C. E.; Bonicalzi, R.

    Characterization of two sets of custom unequal length proportional counters is underway at Pacific Northwest National Laboratory (PNNL). These detectors will be used in measurements to determine the absolute activity concentration of gaseous radionuclides (e.g., {sup 37}Ar). A set of three detectors has been fabricated based on previous PNNL ultra-low-background proportional counter designs and now operate in PNNL's shallow underground counting laboratory. A second set of four counters has also been fabricated using clean assembly of Oxygen-Free High-Conductivity copper components for use in a shielded above-ground counting laboratory. Characterization of both sets of detectors is underway with measurements of backgroundmore » rates, gas gain, and energy resolution. These results will be presented along with a shielding study for the above-ground cave.« less

  19. 78 FR 6828 - Accreditation and Approval of Saybolt LP, as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-31

    ... been approved to gauge and accredited to test petroleum and petroleum products, organic chemicals and... 90810, has been approved to gauge and accredited to test petroleum and petroleum products, organic chemicals and vegetable oils for customs purposes, in accordance with the provisions of 19 CFR 151.12 and 19...

  20. CALiPER Report 24: OLED Luminaires

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miller, N. J.; Leon, F. A.; Davis, J. L.

    2017-08-01

    This report documents an initial investigation of OLED luminaires and summarizes the key features of those products. In addition to photometric testing of four commercial products in independent laboratories, PNNL examined many of the products through teardown testing (disassemblies to identify parts and functionality) in PNNL laboratories. Results of these tests as well as results of stress testing of several OLED luminaires at RTI International have been included.

  1. 75 FR 31745 - Notice of Request for Approval of an Information Collection; National Veterinary Services...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-04

    ...] Notice of Request for Approval of an Information Collection; National Veterinary Services Laboratories... collection associated with the National Veterinary Services Laboratories animal health diagnostic system...: For information on request forms associated with the National Veterinary Services Laboratories animal...

  2. Materials and Methods for Streamlined Laboratory Analysis of Environmental Samples, FY 2016 Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Addleman, Raymond S.; Naes, Benjamin E.; McNamara, Bruce K.

    The International Atomic Energy Agency (IAEA) relies upon laboratory analysis of environmental samples (typically referred to as “swipes”) collected during on-site inspections of safeguarded facilities to support the detection and deterrence of undeclared activities. Unfortunately, chemical processing and assay of the samples is slow and expensive. A rapid, effective, and simple extraction process and analysis method is needed to provide certified results with improved timeliness at reduced costs (principally in the form of reduced labor), while maintaining or improving sensitivity and efficacy. To address these safeguard needs the Pacific Northwest National Laboratory (PNNL) explored and demonstrated improved methods for environmentalmore » sample (ES) analysis. Improvements for both bulk and particle analysis were explored. To facilitate continuity and adoption, the new sampling materials and processing methods will be compatible with existing IAEA protocols for ES analysis. PNNL collaborated with Oak Ridge National Laboratory (ORNL), which performed independent validation of the new bulk analysis methods and compared performance to traditional IAEA’s Network of Analytical Laboratories (NWAL) protocol. ORNL efforts are reported separately. This report describes PNNL’s FY 2016 progress, which was focused on analytical application supporting environmental monitoring of uranium enrichment plants and nuclear fuel processing. In the future the technology could be applied to other safeguard applications and analytes related to fuel manufacturing, reprocessing, etc. PNNL’s FY 2016 efforts were broken into two tasks and a summary of progress, accomplishments and highlights are provided below. Principal progress and accomplishments on Task 1, Optimize Materials and Methods for ICP-MS Environmental Sample Analysis, are listed below. • Completed initial procedure for rapid uranium extraction from ES swipes based upon carbonate-peroxide chemistry (delivered to

  3. 46 CFR 160.052-9 - Recognized laboratory.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Recognized laboratory. 160.052-9 Section 160.052-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS..., Adult and Child § 160.052-9 Recognized laboratory. (a) A manufacturer seeking Coast Guard approval of a...

  4. 46 CFR 160.060-9 - Recognized laboratory.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Recognized laboratory. 160.060-9 Section 160.060-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS..., Adult and Child § 160.060-9 Recognized laboratory. (a) A manufacturer seeking Coast Guard approval of a...

  5. 46 CFR 160.047-7 - Recognized laboratory.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Recognized laboratory. 160.047-7 Section 160.047-7 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS... and Child § 160.047-7 Recognized laboratory. (a) A manufacturer seeking Coast Guard approval of a...

  6. 75 FR 57737 - Notice of Request for Approval of an Information Collection; National Veterinary Services...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-22

    ...] Notice of Request for Approval of an Information Collection; National Veterinary Services Laboratories... Service's intention to request approval of an information collection associated with National Veterinary...' Information Collection Coordinator, at (301) 851-2908. SUPPLEMENTARY INFORMATION: Title: National Veterinary...

  7. Evaluations of Mechanisms for Pu Uptake and Retention within Spherical Resorcinol-Formaldehyde Resin Columns

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Delegard, Calvin H.; Levitskaia, Tatiana G.; Fiskum, Sandra K.

    The unexpected uptake and retention of plutonium (Pu) onto columns containing spherical resorcinol-formaldehyde (sRF) resin during ion exchange testing of Cs (Cs) removal from alkaline tank waste was observed in experiments at both the Pacific Northwest National Laboratory (PNNL) and the Savannah River National Laboratory (SRNL). These observations have raised concern regarding the criticality safety of the Cs removal unit operation within the low-activity waste pretreatment system (LAWPS). Accordingly, studies have been initiated at Washington River Protection Solutions (WRPS), who manages the operations of the Hanford Site tank farms, including the LAWPS, PNNL, and elsewhere to investigate these findings. Asmore » part of these efforts, PNNL has prepared the present report to summarize the laboratory testing observations, evaluate these phenomena in light of published and unpublished technical information, and outline future laboratory testing, as deemed appropriate based on the literature studies, with the goal to elucidate the mechanisms for the observed Pu uptake and retention.« less

  8. Heating and Cooling Master Plan for Fort Bragg, NC, Fiscal Years 2005 to 2030

    DTIC Science & Technology

    2009-02-01

    Pacific Northwest National Labora- tory ( PNNL ) performed an energy use analysis on these buildings in 2005. These buildings are located in 33 specific...electrical equipment the electrical use is provided in the PNNL analysis .* The central chilled water system energy use is reported in cooling chilled...February 2009 C on st ru ct io n E n gi n ee ri n g R es ea rc h L ab or at or y Approved for public release; distribution is unlimited

  9. Design and operation specifications of an active monitoring system for detecting southern resident killer whales

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Deng, Zhiqun; Carlson, Thomas J.; Xu, Jinshan

    2011-09-30

    Before final approval is given to the Snohomish County Public Utility District No. 1 for deploying the first tidal power devices in the United States in an open water environment, a system to manage the potential risk of injury to killer whales due to collision with moving turbine blades must be demonstrated. The Pacific Northwest National Laboratory (PNNL) is tasked with establishing the performance requirements for, constructing, and testing a prototype marine animal alert system for triggering temporary turbine shutdown when there is risk of collision with a killer whale. To develop a system that relies on active sonar twomore » critical areas must be investigated - the target strength of killer whales and the frequency content of commercially available active sonar units. PNNL studied three target strength models: a simple model, the Fourier matching model, and the Kirchoff-ray mode model. Using target strength measurements of bottlenose dolphins obtained by previous researchers and assuming killer whales share similar morphology and structure, PNNL extrapolated the target strength of an adult killer whale 7.5 m in length at a frequency of 67 kHz. To study the frequency content of a commercially available sonar unit, direct measurements of the signal transmitted by the sonar were obtained by using a hydrophone connected to a data acquisition system in both laboratory and field conditions. The measurements revealed that in addition to the primary frequency of 200 kHz, there is a secondary frequency component at 90 kHz, which is within the hearing range of killer whales. The amplitude of the 90-kHz frequency component is above the hearing threshold of killer whales but below the threshold for potential injuries.« less

  10. The uranium from seawater program at PNNL: Overview of marine testing, adsorbent characterization, adsorbent durability, adsorbent toxicity, and deployment studies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gill, Gary A.; Kuo, Li -Jung; Janke, Christopher James

    The Pacific Northwest National Laboratory's (PNNL) Marine Science Laboratory (MSL) located along the coast of Washington State is evaluating the performance of uranium adsorption materials being developed for seawater extraction under realistic marine conditions with natural seawater. Two types of exposure systems were employed in this program: flow-through columns for testing of fixed beds of individual fibers and pellets and a recirculating water flume for testing of braided adsorbent material. Testing consists of measurements of the adsorption of uranium and other elements from seawater as a function of time, typically 42 to 56 day exposures, to determine the adsorbent capacitymore » and adsorption rate (kinetics). Analysis of uranium and other trace elements collected by the adsorbents was conducted following strong acid digestion of the adsorbent with 50% aqua regia using either Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) or Inductively Coupled Plasma Mass Spectrometer (ICP-MS). The ORNL 38H adsorbent had a 56 day adsorption capacity of 3.30 ± 0.68 g U/ kg adsorbent (normalized to a salinity of 35 psu), a saturation adsorption capacity of 4.89 ± 0.83 g U/kg of adsorbent material (normalized to a salinity of 35 psu) and a half-saturation time of 28 10 days. The AF1 adsorbent material had a 56 day adsorption capacity of 3.9 ± 0.2 g U/kg adsorbent material (normalized to a salinity of 35 psu), a saturation capacity of 5.4 ± 0.2 g U/kg adsorbent material (normalized to a salinity of 35 psu) and a half saturation time of 23 2 days. The ORNL amidoxime-based adsorbent materials are not specific for uranium, but also adsorb other elements from seawater. The major doubly charged cations in seawater (Ca and Mg) account for a majority of the cations adsorbed (61% by mass and 74% by molar percent). For the ORNL AF1 adsorbent material, U is the 4th most abundant element adsorbed by mass and 7th most abundant by molar percentage. Marine testing

  11. The uranium from seawater program at PNNL: Overview of marine testing, adsorbent characterization, adsorbent durability, adsorbent toxicity, and deployment studies

    DOE PAGES

    Gill, Gary A.; Kuo, Li -Jung; Janke, Christopher James; ...

    2016-02-07

    The Pacific Northwest National Laboratory's (PNNL) Marine Science Laboratory (MSL) located along the coast of Washington State is evaluating the performance of uranium adsorption materials being developed for seawater extraction under realistic marine conditions with natural seawater. Two types of exposure systems were employed in this program: flow-through columns for testing of fixed beds of individual fibers and pellets and a recirculating water flume for testing of braided adsorbent material. Testing consists of measurements of the adsorption of uranium and other elements from seawater as a function of time, typically 42 to 56 day exposures, to determine the adsorbent capacitymore » and adsorption rate (kinetics). Analysis of uranium and other trace elements collected by the adsorbents was conducted following strong acid digestion of the adsorbent with 50% aqua regia using either Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) or Inductively Coupled Plasma Mass Spectrometer (ICP-MS). The ORNL 38H adsorbent had a 56 day adsorption capacity of 3.30 ± 0.68 g U/ kg adsorbent (normalized to a salinity of 35 psu), a saturation adsorption capacity of 4.89 ± 0.83 g U/kg of adsorbent material (normalized to a salinity of 35 psu) and a half-saturation time of 28 10 days. The AF1 adsorbent material had a 56 day adsorption capacity of 3.9 ± 0.2 g U/kg adsorbent material (normalized to a salinity of 35 psu), a saturation capacity of 5.4 ± 0.2 g U/kg adsorbent material (normalized to a salinity of 35 psu) and a half saturation time of 23 2 days. The ORNL amidoxime-based adsorbent materials are not specific for uranium, but also adsorb other elements from seawater. The major doubly charged cations in seawater (Ca and Mg) account for a majority of the cations adsorbed (61% by mass and 74% by molar percent). For the ORNL AF1 adsorbent material, U is the 4th most abundant element adsorbed by mass and 7th most abundant by molar percentage. Marine testing

  12. Creation of 0.10-cm-1 resolution quantitative infrared spectral libraries for gas samples

    NASA Astrophysics Data System (ADS)

    Sharpe, Steven W.; Sams, Robert L.; Johnson, Timothy J.; Chu, Pamela M.; Rhoderick, George C.; Guenther, Franklin R.

    2002-02-01

    The National Institute of Standards and Technology (NIST) and the Pacific Northwest National Laboratory (PNNL) are independently creating quantitative, approximately 0.10 cm-1 resolution, infrared spectral libraries of vapor phase compounds. The NIST library will consist of approximately 100 vapor phase spectra of volatile hazardous air pollutants (HAPs) and suspected greenhouse gases. The PNNL library will consist of approximately 400 vapor phase spectra associated with DOE's remediation mission. A critical part of creating and validating any quantitative work involves independent verification based on inter-laboratory comparisons. The two laboratories use significantly different sample preparation and handling techniques. NIST uses gravimetric dilution and a continuous flowing sample while PNNL uses partial pressure dilution and a static sample. Agreement is generally found to be within the statistical uncertainties of the Beer's law fit and less than 3 percent of the total integrated band areas for the 4 chemicals used in this comparison. There does appear to be a small systematic difference between the PNNL and NIST data, however. Possible sources of the systematic difference will be discussed as well as technical details concerning the sample preparation and the procedures for overcoming instrumental artifacts.

  13. 9 CFR 590.580 - Laboratory tests and analyses.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Laboratory tests and analyses. 590.580 Section 590.580 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... sequence, frequency, and approved laboratory methods as prescribed by the AMS Science Division Director...

  14. 9 CFR 590.580 - Laboratory tests and analyses.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Laboratory tests and analyses. 590.580 Section 590.580 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... sequence, frequency, and approved laboratory methods as prescribed by the AMS Science Division Director...

  15. 9 CFR 590.580 - Laboratory tests and analyses.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Laboratory tests and analyses. 590.580 Section 590.580 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... sequence, frequency, and approved laboratory methods as prescribed by the AMS Science Division Director...

  16. 2014 Fermilab Laboratory Directoed Research & Development Annual Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    W. Wester

    After initiation by the Fermilab Laboratory Director, a team from the senior Laboratory leadership and a Laboratory Directed Research and Development (LDRD) Advisory Committee developed an implementation plan for LDRD at Fermilab for the first time. This implementation was captured in the approved Fermilab 2014 LDRD Program Plan and followed directions and guidance from the Department of Energy (DOE) order, DOE O 413.2B, a “Roles, Responsibilities, and Guidelines, …” document, and examples of best practices at other DOE Office of Science Laboratories. At Fermilab, a FY14 midyear Call for Proposals was issued. A LDRD Selection Committee evaluated those proposals thatmore » were received and provided a recommendation to the Laboratory Director who approved seven LDRD projects. This Annual Report focuses on the status of those seven projects and provides an overview of the current status of LDRD at Fermilab. The seven FY14 LDRD approved projects had a date of initiation late in FY14 such that this report reflects approximately six months of effort approximately through January 2015. The progress of these seven projects, the subsequent award of six additional new projects beginning in FY15, and preparations for the issuance of the FY16 Call for Proposals indicates that LDRD is now integrated into the overall annual program at Fermilab. All indications are that LDRD is improving the scientific and technical vitality of the Laboratory and providing new, novel, or cutting edge projects carried out at the forefront of science and technology and aligned with the mission and strategic visions of Fermilab and the Department of Energy.« less

  17. 78 FR 66757 - Accreditation and Approval of Amspec Services, LLC, as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-06

    ... Services, LLC, has been approved to gauge and accredited to test petroleum and petroleum products, organic chemicals and vegetable oils for customs purposes for the next three years as of February 20, 2013. DATES... 07036, has been approved to gauge and accredited to test petroleum and petroleum products, organic...

  18. Novel Methods to Explore Building Energy Sensitivity to Climate and Heat Waves Using PNNL's BEND Model

    NASA Astrophysics Data System (ADS)

    Burleyson, C. D.; Voisin, N.; Taylor, T.; Xie, Y.; Kraucunas, I.

    2017-12-01

    The DOE's Pacific Northwest National Laboratory (PNNL) has been developing the Building ENergy Demand (BEND) model to simulate energy usage in residential and commercial buildings responding to changes in weather, climate, population, and building technologies. At its core, BEND is a mechanism to aggregate EnergyPlus simulations of a large number of individual buildings with a diversity of characteristics over large spatial scales. We have completed a series of experiments to explore methods to calibrate the BEND model, measure its ability to capture interannual variability in energy demand due to weather using simulations of two distinct weather years, and understand the sensitivity to the number and location of weather stations used to force the model. The use of weather from "representative cities" reduces computational costs, but often fails to capture spatial heterogeneity that may be important for simulations aimed at understanding how building stocks respond to a changing climate (Fig. 1). We quantify the potential reduction in temperature and load biases from using an increasing number of weather stations across the western U.S., ranging from 8 to roughly 150. Using 8 stations results in an average absolute summertime temperature bias of 4.0°C. The mean absolute bias drops to 1.5°C using all available stations. Temperature biases of this magnitude translate to absolute summertime mean simulated load biases as high as 13.8%. Additionally, using only 8 representative weather stations can lead to a 20-40% bias of peak building loads under heat wave or cold snap conditions, a significant error for capacity expansion planners who may rely on these types of simulations. This analysis suggests that using 4 stations per climate zone may be sufficient for most purposes. Our novel approach, which requires no new EnergyPlus simulations, could be useful to other researchers designing or calibrating aggregate building model simulations - particularly those looking at

  19. 46 CFR 194.05-5 - Chemicals in the chemistry laboratory.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Chemicals in the chemistry laboratory. 194.05-5 Section....05-5 Chemicals in the chemistry laboratory. (a) Small working quantities of chemical stores in the chemistry laboratory which have been removed from the approved shipping container need not be marked or...

  20. 46 CFR 194.05-5 - Chemicals in the chemistry laboratory.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Chemicals in the chemistry laboratory. 194.05-5 Section....05-5 Chemicals in the chemistry laboratory. (a) Small working quantities of chemical stores in the chemistry laboratory which have been removed from the approved shipping container need not be marked or...

  1. 46 CFR 194.05-5 - Chemicals in the chemistry laboratory.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Chemicals in the chemistry laboratory. 194.05-5 Section....05-5 Chemicals in the chemistry laboratory. (a) Small working quantities of chemical stores in the chemistry laboratory which have been removed from the approved shipping container need not be marked or...

  2. 46 CFR 194.05-5 - Chemicals in the chemistry laboratory.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Chemicals in the chemistry laboratory. 194.05-5 Section....05-5 Chemicals in the chemistry laboratory. (a) Small working quantities of chemical stores in the chemistry laboratory which have been removed from the approved shipping container need not be marked or...

  3. 46 CFR 194.05-5 - Chemicals in the chemistry laboratory.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Chemicals in the chemistry laboratory. 194.05-5 Section....05-5 Chemicals in the chemistry laboratory. (a) Small working quantities of chemical stores in the chemistry laboratory which have been removed from the approved shipping container need not be marked or...

  4. Pacific Northwest National Laboratory Campus Radionuclide Air Emissions Report for Calendar Year 2015

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Snyder, Sandra F.; Barnett, J. Matthew; Bisping, Lynn E.

    This report documents radionuclide air emissions that result in the 2015 highest effective dose equivalent (EDE) to an offsite member of the public, referred to as the maximally exposed individual (MEI). The report has been prepared in compliance with the Code of Federal Regulations (CFR), Title 40, Protection of the Environment, Part 61, National Emission Standards for Hazardous Air Pollutants (NESHAP), Subpart H, “National Emission Standards for Emissions of Radionuclides Other than Radon from Department of Energy Facilities” and Washington Administrative Code (WAC) Chapter 246-247, “Radiation Protection–Air Emissions.” The dose to the PNNL Campus MEI from routine major and minormore » point source emissions in 2015 from PNNL Campus sources is 2.6E-4 mrem (2.6E-6 mSv) EDE. The dose from all fugitive sources is 1.8E-6 mrem (1.8E-8 mSv) EDE. The dose from radon emissions is 4.4E-8 mrem (4.4E-10 mSv) EDE. No nonroutine emissions occurred in 2015. The total radiological dose to the MEI from all PNNL Campus radionuclide emissions, including fugitive emissions and radon, is 2.6E-4 mrem (2.6E-6 mSv) EDE, or more than 10,000 times less than the federal and state standard of 10 mrem/yr, with which the PNNL Campus is in compliance.« less

  5. 46 CFR 159.010-15 - Contracting inspections and tests or transferrals to another laboratory or person.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Contracting inspections and tests or transferrals to another laboratory or person. 159.010-15 Section 159.010-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL APPROVAL OF EQUIPMENT AND MATERIALS Independent Laboratory...

  6. 46 CFR 159.010-15 - Contracting inspections and tests or transferrals to another laboratory or person.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Contracting inspections and tests or transferrals to another laboratory or person. 159.010-15 Section 159.010-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL APPROVAL OF EQUIPMENT AND MATERIALS Independent Laboratory...

  7. The Pitfalls of Companion Diagnostics: Evaluation of Discordant EGFR Mutation Results from a Clinical Laboratory and a Central Laboratory.

    PubMed

    Turner, Scott A; Peterson, Jason D; Pettus, Jason R; de Abreu, Francine B; Amos, Christopher I; Dragnev, Konstantin H; Tsongalis, Gregory J

    2016-05-01

    Accurate identification of somatic mutations in formalin-fixed, paraffin-embedded tumor tissue is required for enrollment into clinical trials for many novel targeted therapeutics, including trials requiring EGFR mutation status in non-small-cell lung carcinomas. Central clinical trial laboratories contracted to perform this analysis typically rely on US Food and Drug Administration-approved targeted assays to identify these mutations. We present two cases in which central laboratories inaccurately reported EGFR mutation status because of improper identification and isolation of tumor material and failure to accurately report assay limitations, resulting in enrollment denial. Such cases highlight the need for increased awareness by clinical trials of the limitation of these US Food and Drug Administration-approved assays and the necessity for a mechanism to reevaluate discordant results by alternative laboratory-developed procedures, including clinical next-generation sequencing. Copyright © 2016 American Society for Investigative Pathology and the Association for Molecular Pathology. Published by Elsevier Inc. All rights reserved.

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hu, T.A.

    This is the final sample analysis report for tank 241-BX-104 (BX-104), cores 126 and 127. Two segments from each core yielded a total of 11 samples which were analyzed. The data quality objectives (DQOs) applicable to this sampling event were the Safety Screening DQO (Dukelow et al. 1995) and the Organic Safety DQO (Turner et al. 1995). The samples were received, extruded and analyzed at PNNL 325 Analytical Chemistry Laboratory (ACL). The analyses were performed in accordance with the Sample Analysis Plan (Gretsinger 1996) and indicated that the tank is safe with respect to the criteria in the Safety Screeningmore » and Organic DQO. Detailed analytical results were described in the analytical laboratory 45-day Report (Attachment 1, WHC-SD-WM-DP-171, REV. 0) and final report (Attachment 2, PNL-BX-104 REV.1) prepared by PNNL, 325 Laboratory. Corrections and/or exceptions to the PNNL final report are provided.« less

  9. Side-by-Side Field Evaluation of Highly Insulating Windows in the PNNL Lab Homes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Widder, Sarah H.; Parker, Graham B.; Baechler, Michael C.

    2012-08-01

    To examine the energy, air leakage, and thermal performance of highly insulating windows, a field evaluation was undertaken in a matched pair of all-electric, factory-built “Lab Homes” located on the Pacific Northwest National Laboratory (PNNL) campus in Richland, Washington. The “baseline” Lab Home B was retrofitted with “standard” double-pane clear aluminum-frame slider windows and patio doors, while the “experimental” Lab Home A was retrofitted with Jeld-Wen® triple-pane vinyl-frame slider windows and patio doors with a U-factor of 0.2 and solar heat gain coefficient of 0.19. To assess the window, the building shell air leakage, energy use, and interior temperatures ofmore » each home were compared during the 2012 winter heating and summer cooling seasons. The measured energy savings in Lab Home B averaged 5,821 watt-hours per day (Wh/day) during the heating season and 6,518 Wh/day during the cooling season. The overall whole-house energy savings of Lab Home B compared to Lab Home A are 11.6% ± 1.53% for the heating season and 18.4 ± 2.06% for the cooling season for identical occupancy conditions with no window coverings deployed. Extrapolating these energy savings numbers based on typical average heating degree days and cooling degree days per year yields an estimated annual energy savings of 12.2%, or 1,784 kWh/yr. The data suggest that highly insulating windows are an effective energy-saving measure that should be considered for high-performance new homes and in existing retrofits. However, the cost effectiveness of the measure, as determined by the simple payback period, suggests that highly insulating window costs continue to make windows difficult to justify on a cost basis alone. Additional reductions in costs via improvements in manufacturing and/or market penetration that continue to drive down costs will make highly insulating windows much more viable as a cost-effective energy efficiency measure. This study also illustrates that

  10. 76 FR 55082 - Re-Accreditation and Re-Approval Intertek Testing Services as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-06

    ... DEPARTMENT OF HOMELAND SECURITY Bureau of Customs and Border Protection Re-Accreditation and Re... Border Protection, Department of Homeland Security. ACTION: Notice of re-approval of Intertek Testing..., Texas 78406, has been re-approved to gauge petroleum and petroleum products, organic chemicals and...

  11. 78 FR 7442 - Accreditation and Approval of Chemical and Petrochemical Inspections, LP, as a Commercial Gauger...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-01

    ... approved to gauge and accredited to test petroleum and petroleum products, organic chemicals and vegetable... approved to gauge and accredited to test petroleum and petroleum products, organic chemicals and vegetable... Chemical and Petrochemical Inspections, LP, as a Commercial Gauger and Laboratory AGENCY: U.S. Customs and...

  12. 77 FR 31359 - Medicare and Medicaid Programs; Announcement of the Re-Approval of the Joint Commission as an...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-25

    ... Organization Under the Clinical Laboratory Improvement Amendments of 1988 AGENCY: Centers for Medicare... Commission for re-approval as an accreditation organization for clinical laboratories under the Clinical... On October 31, 1988, the Congress enacted the Clinical Laboratory Improvement Amendments of 1988...

  13. Evaluation of Life History Diversity, Habitat Connectivity, and Survival Benefits Associated with Habitat Restoration Actions in the Lower Columbia River and Estuary, Annual Report 2011

    DTIC Science & Technology

    2012-05-01

    PNNL -21202 Prepared for the U.S. Army Corps of Engineers, Portland District, under an Interagency Agreement with the U.S. Department of Energy...KE Buenau EM Dawley NK Sather JD Tagestad JR Skalski May 2012 Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting...ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION/AVAILABILITY STATEMENT Approved for public release; distribution unlimited 13

  14. 75 FR 51282 - Approval of American Cargo Assurance, as a Commercial Gauger

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-19

    ..., LA 70663, has been approved to gauge petroleum and petroleum products for customs purposes, in.... Ira S. Reese, Executive Director, Laboratories and Scientific Services. [FR Doc. 2010-20532 Filed 8-18...

  15. The continued value of disk diffusion for assessing antimicrobial susceptibility in clinical laboratories: report from the Clinical and Laboratory Standards Institute Methods Development and Standardization Working Group.

    PubMed

    Humphries, Romney M; Kircher, Susan; Ferrell, Andrea; Krause, Kevin M; Malherbe, Rianna; Hsiung, Andre; Burnham, C A

    2018-05-09

    Expedited pathways to antimicrobial agent approval by the United States Food and Drug Administration (FDA) have led to increased delays between drug approval and the availability of FDA-cleared antimicrobial susceptibility testing (AST) devices. Antimicrobial disks for use with disk diffusion testing are among the first AST devices available to clinical laboratories. However, many laboratories are reluctant to implement a disk diffusion method for a variety of reasons, including dwindling proficiency with this method, interruptions to laboratory workflow, uncertainty surrounding the quality and reliability of a disk diffusion test, and perceived need to report an MIC to clinicians. This mini-review provides a report from the Clinical and Laboratory Standards Institute Working Group on Methods Development and Standardization on the current standards and clinical utility of disk diffusion testing. Copyright © 2018 American Society for Microbiology.

  16. 46 CFR 160.151-27 - Approval inspections and tests for inflatable liferafts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...; and paragraph 5.17, a prototype inflatable liferaft of each design submitted for Coast Guard approval... laboratory's inspection of the prototype liferaft under § 160.151-13(a) satisfies the requirements of...

  17. Verification of performance specifications for a US Food and Drug Administration-approved molecular microbiology test: Clostridium difficile cytotoxin B using the Becton, Dickinson and Company GeneOhm Cdiff assay.

    PubMed

    Schlaberg, Robert; Mitchell, Michael J; Taggart, Edward W; She, Rosemary C

    2012-01-01

    US Food and Drug Administration (FDA)-approved diagnostic tests based on molecular genetic technologies are becoming available for an increasing number of microbial pathogens. Advances in technology and lower costs have moved molecular diagnostic tests formerly performed for research purposes only into much wider use in clinical microbiology laboratories. To provide an example of laboratory studies performed to verify the performance of an FDA-approved assay for the detection of Clostridium difficile cytotoxin B compared with the manufacturer's performance standards. We describe the process and protocols used by a laboratory for verification of an FDA-approved assay, assess data from the verification studies, and implement the assay after verification. Performance data from the verification studies conducted by the laboratory were consistent with the manufacturer's performance standards and the assay was implemented into the laboratory's test menu. Verification studies are required for FDA-approved diagnostic assays prior to use in patient care. Laboratories should develop a standardized approach to verification studies that can be adapted and applied to different types of assays. We describe the verification of an FDA-approved real-time polymerase chain reaction assay for the detection of a toxin gene in a bacterial pathogen.

  18. 2005 Annual Report Summer Research Institute Interfacial and Condensed Phase Chemical Physics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barlow, Stephan E.

    2005-11-15

    The Pacific Northwest National Laboratory (PNNL) hosted its second annual Summer Research Institute in Interfacial and Condensed Phase Chemical Physics from May through September 2005. During this period, sixteen PNNL scientists hosted fourteen young scientists from eleven different universities. Of the fourteen participants, twelve were graduate students; one was a postdoctoral fellow; and one was a university faculty member.

  19. TSCA Experimental Release Application Approved for Pseudomonas putida Strains (fact sheet)

    EPA Pesticide Factsheets

    In 1998, EPA approved the TERAs R98-0004/5 submitted by the National Explosives Waste Technology & Evaluation Center (NEWTEC) and the Oak Ridge National Laboratory for field trials of two modified strains of Pseudomonas putida (P.putida).

  20. 77 FR 12866 - Accreditation and Approval of Coastal Gulf and International, Inc. as a Commercial Gauger and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-02

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection Accreditation and Approval of Coastal Gulf and International, Inc. as a Commercial Gauger and Laboratory AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION: Notice of accreditation and approval of Coastal Gulf and...

  1. 30 CFR 18.99 - Notice of approval or disapproval; letters of approval and approval plates.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... approval or disapproval of the machine. (a) If the qualified electrical representative recommends field..., DEPARTMENT OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MOTOR-DRIVEN MINE EQUIPMENT AND ACCESSORIES Field Approval of Electrically Operated Mining Equipment § 18.99 Notice of approval or...

  2. 30 CFR 18.99 - Notice of approval or disapproval; letters of approval and approval plates.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... approval or disapproval of the machine. (a) If the qualified electrical representative recommends field..., DEPARTMENT OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MOTOR-DRIVEN MINE EQUIPMENT AND ACCESSORIES Field Approval of Electrically Operated Mining Equipment § 18.99 Notice of approval or...

  3. 49 CFR 451.16 - Action by approval authority-individual approval.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... GUARD, DEPARTMENT OF HOMELAND SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of New Containers § 451.16 Action by approval authority-individual approval. (a) The...

  4. 49 CFR 451.16 - Action by approval authority-individual approval.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... GUARD, DEPARTMENT OF HOMELAND SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of New Containers § 451.16 Action by approval authority-individual approval. (a) The...

  5. 49 CFR 451.16 - Action by approval authority-individual approval.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... GUARD, DEPARTMENT OF HOMELAND SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of New Containers § 451.16 Action by approval authority-individual approval. (a) The...

  6. 49 CFR 451.16 - Action by approval authority-individual approval.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... GUARD, DEPARTMENT OF HOMELAND SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of New Containers § 451.16 Action by approval authority-individual approval. (a) The...

  7. 49 CFR 451.16 - Action by approval authority-individual approval.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... GUARD, DEPARTMENT OF HOMELAND SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of New Containers § 451.16 Action by approval authority-individual approval. (a) The...

  8. 46 CFR 159.007-3 - Production inspections and tests: Independent laboratory's procedures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Production inspections and tests: Independent laboratory's procedures. 159.007-3 Section 159.007-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL APPROVAL OF EQUIPMENT AND MATERIALS Production Inspection and Tests of...

  9. 46 CFR 159.007-3 - Production inspections and tests: Independent laboratory's procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Production inspections and tests: Independent laboratory's procedures. 159.007-3 Section 159.007-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL APPROVAL OF EQUIPMENT AND MATERIALS Production Inspection and Tests of...

  10. International Symposium on Space Technology and Science (27th) (ISTA) Panel Discussion on Space Solar Power Systems, held in Tsukuba, Japan on 10 July 2009

    DTIC Science & Technology

    2010-01-01

    REPORT DOCUMENTATION PAGE Form Approved OMB No. 0704-0188 The public reporting burden for this collection of information is estimated to average...ACRONYM(S) AOARD 11. SPONSOR/MONITOR’S REPORT NUMBER(S) CSP-091013 12. DISTRIBUTION/AVAILABILITY STATEMENT Approved for public release; U.S...Also, significant relevant R&D continued to be conducted by Texas A&M University (TAMU), 
 3
 the Battelle Memorial Institute, through PNNL , and

  11. North Pacific Acoustic Laboratory and Deep Water Acoustics

    DTIC Science & Technology

    2015-09-30

    range acoustic systems, whether for acoustic surveillance, communication, or remote sensing of the ocean interior . The data from the NPAL network, and...1 DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. North Pacific Acoustic Laboratory and Deep Water... Acoustics PI James A. Mercer Applied Physics Laboratory, University of Washington 1013 NE 40th Street Seattle, WA 98105 phone: (206) 543-1361 fax

  12. [Recent trends in the standardization of laboratory automation].

    PubMed

    Tao, R; Yamashita, K

    2000-10-01

    Laboratory automation systems have been introduced to many clinical laboratories since early 1990s. Meanwhile, it was found that the difference in the specimen tube dimensions, specimen identification formats, specimen carrier transportation equipment architecture, electromechanical interfaces between the analyzers and the automation systems was preventing the systems from being introduced to a wider extent. To standardize the different interfaces and reduce the cost necessary for the laboratory automation, NCCLS and JCCLS started establishing standards for the laboratory automation in 1996 and 1997 respectively. NCCLS has published five proposed standards which that are expected to be approved by the end of 2000.

  13. Pre-Employment Laboratory Training. A Guide for Coordinated Vocational-Academic Education Shop and Laboratory Instructors. Revised.

    ERIC Educational Resources Information Center

    East Texas State Univ., Commerce. Occupational Curriculum Lab.

    This guide is designed to serve as a reference for both beginning and experienced teachers in a preemployment laboratory that is part of a coordinated vocational-academic education program. Addressed in the individual sections of the guide are the following topics: student eligibility and approved coordinated vocational-academic programs, safety…

  14. Does social approval stimulate prosocial behavior? Evidence from a field experiment in the residential electricity market

    NASA Astrophysics Data System (ADS)

    Yoeli, Erez

    At least since Veblen (1899), economists have proposed that people do good because they desire "social approval" and want to look good in front of others. Evidence from the laboratory supports this claim, but is difficult to generalize due to the unrealistic degree of scrutiny in a laboratory environment. I administer a field experiment to test the potency of social approval in a realistic and policy relevant setting. In the experiment I solicit 7893 customers of a large electric utility for a program that helps prevent blackouts. I vary whether their decision to participate in the program is revealed to their neighbors. Customers whose decision is revealed are 1.5% more likely to sign up than those whose decision is anonymous when their decision is framed as a contribution to a public good. Social approval increases participation more than offering subjects a $25 incentive, and its effect is large relative to the mean sign-up rate of 4.1%. I explore whether social approval contributes to crowding out and conditionally cooperative behavior, but the evidence is inconclusive.

  15. Scientists View Battery Under Microscope

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2015-04-10

    PNNL researchers use a special microscope setup that shows the inside of a battery as it charges and discharges. This battery-watching microscope is located at EMSL, DOE's Environmental Molecular Sciences Laboratory that resides at PNNL. Researchers the world over can visit EMSL and use special instruments like this, many of which are the only one of their kind available to scientists.

  16. Scientists View Battery Under Microscope

    ScienceCinema

    None

    2018-01-16

    PNNL researchers use a special microscope setup that shows the inside of a battery as it charges and discharges. This battery-watching microscope is located at EMSL, DOE's Environmental Molecular Sciences Laboratory that resides at PNNL. Researchers the world over can visit EMSL and use special instruments like this, many of which are the only one of their kind available to scientists.

  17. Requirements for Xenon International

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hayes, James C.; Ely, James H.; Haas, Derek A.

    2015-12-30

    This document defines the requirements for the new Xenon International radioxenon system. The output of this project will be a Pacific Northwest National Laboratory (PNNL) developed prototype and a manufacturer-developed production prototype. The two prototypes are intended to be as close to matching as possible; this will be facilitated by overlapping development cycles and open communication between PNNL and the manufacturer.

  18. Marketing approval for the lithotripter.

    PubMed

    Nightingale, S L; Young, F E

    1986-01-01

    In December 1984, the Food and Drug Administration (FDA) granted Dornier Systems (FRG) approval to market the external shock wave lithotripter (ESWL) in the USA. The Medical Device Amendments of the Food, Drug, and Cosmetic Act require that the FDA evaluate the safety and effectiveness of medical devices intended for commercial distribution in the U.S. Such evaluation includes basic scientific studies, animal testing, and investigational studies in human subjects, culminating in a judgment concerning acceptable risks in terms of anticipated benefits, and whether the device is effective for its intended use. Prior to human studies in West Germany, Dornier had evaluated the destruction of stones of varying composition, measured the rate and energy of stone destruction, and tested blood samples and lymphocyte cultures exposed to shock waves. In addition, studies in both rats and dogs had demonstrated the feasibility of the technique and evidence of safety. Such data are provided by manufacturers when applying for an investigational device exemption (IDE) from the FDA, which permits clinical studies in humans; such studies also require the approval of an Institutional Review Board. The FDA approved Dornier's IDE, allowing human investigational use of the ESWL in facilities in the U.S., conducted concurrently with similar studies in West Germany. Upon completion of clinical trials, data acquired in vitro, in laboratory animals, and in human investigations are submitted to the FDA for a premarked approval application (PMAA). The Agency was given 6 months to make a decision, taking into consideration the recommendation of an advisory panel of experts from outside the Agency who had reviewed the same data. In its evaluation of the ESWL for safety and effectiveness, the FDA considered the question of alternative practices and procedures to treat nephrolithiasis, including percutaneous nephrolithotomy and open surgical procedures, and the adverse effects of such procedures

  19. Mechanisms and Dynamics of Abiotic and Biotic Interactions at Environmental Interfaces

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Roso, Kevin M.

    The Stanford EMSI (SEMSI) was established in 2004 through joint funding by the National Science Foundation and the OBER-ERSD. It encompasses a number of universities and national laboratories. The PNNL component of the SEMSI is funded by ERSD and is the focus of this report. This component has the objective of providing theory support to the SEMSI by bringing computational capabilities and expertise to bear on important electron transfer problems at mineral/water and mineral/microbe interfaces. PNNL staff member Dr. Kevin Rosso, who is also ''matrixed'' into the Environmental Molecular Sciences Laboratory (EMSL) at PNNL, is a co-PI on the SEMSImore » project and the PNNL lead. The EMSL computational facilities being applied to the SEMSI project include the 11.8 teraflop massively-parallel supercomputer. Science goals of this EMSL/SEMSI partnership include advancing our understanding of: (1) The kinetics of U(VI) and Cr(VI) reduction by aqueous and solid-phase Fe(II), (2) The structure of mineral surfaces in equilibrium with solution, and (3) Mechanisms of bacterial electron transfer to iron oxide surfaces via outer-membrane cytochromes.« less

  20. Increasing Efficiency of Fecal Coliform Testing Through EPA-Approved Alternate Method Colilert*-18

    NASA Technical Reports Server (NTRS)

    Cornwell, Brian

    2017-01-01

    The 21 SM 9221 E multiple-tube fermentation method for fecal coliform analysis requires a large time and reagent investment for the performing laboratory. In late 2010, the EPA approved an alternative procedure for the determination of fecal coliforms designated as Colilert*-18. However, as of late 2016, only two VELAP-certified laboratories in the Commonwealth of Virginia have been certified in this method.

  1. 46 CFR 160.060-9 - Recognized laboratory.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Recognized laboratory. 160.060-9 Section 160.060-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Unicellular Polyethylene Foam...

  2. 46 CFR 160.052-9 - Recognized laboratory.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 6 2013-10-01 2013-10-01 false Recognized laboratory. 160.052-9 Section 160.052-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Unicellular Plastic Foam...

  3. 46 CFR 160.052-9 - Recognized laboratory.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Recognized laboratory. 160.052-9 Section 160.052-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Unicellular Plastic Foam...

  4. 46 CFR 160.060-9 - Recognized laboratory.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 6 2013-10-01 2013-10-01 false Recognized laboratory. 160.060-9 Section 160.060-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Unicellular Polyethylene Foam...

  5. 46 CFR 160.060-9 - Recognized laboratory.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 6 2014-10-01 2014-10-01 false Recognized laboratory. 160.060-9 Section 160.060-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Unicellular Polyethylene Foam...

  6. 46 CFR 160.060-9 - Recognized laboratory.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 6 2012-10-01 2012-10-01 false Recognized laboratory. 160.060-9 Section 160.060-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Unicellular Polyethylene Foam...

  7. 46 CFR 160.052-9 - Recognized laboratory.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 6 2012-10-01 2012-10-01 false Recognized laboratory. 160.052-9 Section 160.052-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Unicellular Plastic Foam...

  8. 46 CFR 160.052-9 - Recognized laboratory.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 6 2014-10-01 2014-10-01 false Recognized laboratory. 160.052-9 Section 160.052-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Unicellular Plastic Foam...

  9. 46 CFR 164.009-21 - Laboratory report.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) Description of the specimens tested if the specimens are prepared from composite material. (i) If the test was... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL MATERIALS Noncombustible Materials for Merchant Vessels § 164.009-21 Laboratory...

  10. 78 FR 29376 - Accreditation and Approval of Quality Custom Inspections & Laboratories, LLC, as a Commercial...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-20

    ..., has been approved to gauge and accredited to test petroleum and petroleum products, organic chemicals... petroleum and petroleum products, organic chemicals and vegetable oils for customs purposes, in accordance...

  11. 78 FR 57408 - Accreditation and Approval of Saybolt, LP, as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-18

    ..., has been approved to gauge and accredited to test petroleum and petroleum products, organic chemicals... accredited to test petroleum and petroleum products, organic chemicals and vegetable oils for customs...

  12. 78 FR 52556 - Accreditation and Approval of Saybolt, LP, as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-23

    ..., has been approved to gauge and accredited to test petroleum and petroleum products, organic chemicals... accredited to test petroleum and petroleum products, organic chemicals and vegetable oils for customs...

  13. 2006 Annual Report Summer Research Institute Interfacial and Condensed Phase Chemical Physics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Avery, Nikki B.; Barlow, Stephan E.

    2006-11-10

    The Pacific Northwest National Laboratory (PNNL) hosted its third annual Summer Research Institute in Interfacial and Condensed Phase Chemical Physics from May through September 2006. During this period, twenty PNNL scientists hosted twenty-seven scientists from twenty-five different universities. Of the twenty-seven participants, one was a graduating senior; twenty-one were graduate students; one was a postdoctoral fellow; and four were university faculty members.

  14. 78 FR 39001 - Accreditation and Approval of Saybolt, LP, as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-28

    ..., has been approved to gauge and accredited to test petroleum and petroleum products, organic chemicals... gauge and accredited to test petroleum and petroleum products, organic chemicals and vegetable oils for...

  15. EMSL Quarterly Highlights Report Second Quarter, Fiscal Year 2010 (January 1, 2010 through March 31, 2010)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    West, Staci A.; Showalter, Mary Ann; Manke, Kristin L.

    2010-04-20

    The Environmental Molecular Sciences Laboratory (EMSL) is a U.S. Department of Energy (DOE) national scientific user facility located at Pacific Northwest National Laboratory (PNNL) in Richland, Washington. EMSL is operated by PNNL for the DOE-Office of Biological and Environmental Research. At one location, EMSL offers a comprehensive array of leading-edge resources and expertise. Access to the instrumentation and expertise is obtained on a peer-reviewed proposal basis. Staff members work with researchers to expedite access to these capabilities. The "EMSL Quarterly Highlights Report" documents current research and activities of EMSL staff and users.

  16. 46 CFR 160.049-8 - Recognized laboratory.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Recognized laboratory. 160.049-8 Section 160.049-8 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Specification for a Buoyant Cushion Plastic Foam § 160.049-8...

  17. 46 CFR 160.049-8 - Recognized laboratory.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Recognized laboratory. 160.049-8 Section 160.049-8 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Specification for a Buoyant Cushion Plastic Foam § 160.049-8...

  18. 46 CFR 160.047-7 - Recognized laboratory.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 6 2012-10-01 2012-10-01 false Recognized laboratory. 160.047-7 Section 160.047-7 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Kapok or Fibrous Glass, Adult...

  19. 46 CFR 160.047-7 - Recognized laboratory.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 6 2014-10-01 2014-10-01 false Recognized laboratory. 160.047-7 Section 160.047-7 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Kapok or Fibrous Glass, Adult...

  20. 46 CFR 160.047-7 - Recognized laboratory.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 6 2013-10-01 2013-10-01 false Recognized laboratory. 160.047-7 Section 160.047-7 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Kapok or Fibrous Glass, Adult...

  1. 46 CFR 160.047-7 - Recognized laboratory.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Recognized laboratory. 160.047-7 Section 160.047-7 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Specification for a Buoyant Vest, Kapok or Fibrous Glass, Adult...

  2. 46 CFR 160.049-8 - Recognized laboratory.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 6 2014-10-01 2014-10-01 false Recognized laboratory. 160.049-8 Section 160.049-8 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Specification for a Buoyant Cushion Plastic Foam § 160.049-8...

  3. 75 FR 57479 - Accreditation and Approval of Inspectorate America Corporation, as a Commercial Gauger and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-21

    ... laboratories. http://cbp.gov/xp/cgov/import/operations-- support/labs--scientific--svcs[sol]commercial--gaugers[sol]. DATES: The accreditation and approval of Inspectorate America Corporation, as commercial gauger...

  4. 77 FR 47428 - Accreditation and Approval of Saybolt LP, as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-08

    ..., Saybolt LP, 201 Deerwood Glen Drive, Deer Park, TX 77536, has been approved to gauge and accredited to test petroleum and petroleum products, organic chemicals and vegetable oils for customs purposes, in...

  5. 78 FR 66756 - Accreditation and Approval of Saybolt, LP, as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-06

    ..., organic chemicals and vegetable oils for customs purposes for the next three years as of July 18, 2013... been approved to gauge and accredited to test petroleum and petroleum products, organic chemicals and...

  6. Vegetation studies, National Training Center, Fort Irwin, California

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brandt, C.A.; Rickard, W.H.; Cadoret, N.A.

    1997-09-01

    During the spring of 1992, the Pacific Northwest National Laboratory (PNNL) conducted surveys of the Avawatz and Granite mountains springs for the National Training Center (NTC) to evaluate the occurrence of sensitive plant species in these areas. PNNL also conducted a survey of the eastern outwash of the Paradise Range for the occurrence of Lane Mountain milk vetch (Astragalus jaegerianus). In spring of 1993, PNNL conducted an additional study of Lane Mountain milk vetch on the NTC to determine habitat characteristics for this plant and to develop a method for predicting its potential occurrence, based on simple habitat attributes. Themore » results of these studies are itemized.« less

  7. 42 CFR 84.30 - Certificates of approval; scope of approval.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Certificates of approval; scope of approval. 84.30 Section 84.30 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Approval and...

  8. 42 CFR 84.30 - Certificates of approval; scope of approval.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Certificates of approval; scope of approval. 84.30 Section 84.30 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Approval and...

  9. 42 CFR 84.30 - Certificates of approval; scope of approval.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Certificates of approval; scope of approval. 84.30 Section 84.30 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Approval and...

  10. 42 CFR 84.30 - Certificates of approval; scope of approval.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Certificates of approval; scope of approval. 84.30 Section 84.30 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Approval and...

  11. 42 CFR 84.30 - Certificates of approval; scope of approval.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Certificates of approval; scope of approval. 84.30 Section 84.30 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Approval and...

  12. 49 CFR 451.13 - Action by approval authority-approval by design type.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) COAST GUARD, DEPARTMENT OF HOMELAND SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of New Containers § 451.13 Action by approval authority-approval by design type. (a) The... of safety approval plates to the containers. Absence of individual inspections will not relieve the...

  13. 49 CFR 451.13 - Action by approval authority-approval by design type.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) COAST GUARD, DEPARTMENT OF HOMELAND SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of New Containers § 451.13 Action by approval authority-approval by design type. (a) The... of safety approval plates to the containers. Absence of individual inspections will not relieve the...

  14. 49 CFR 451.13 - Action by approval authority-approval by design type.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...) COAST GUARD, DEPARTMENT OF HOMELAND SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of New Containers § 451.13 Action by approval authority-approval by design type. (a) The... of safety approval plates to the containers. Absence of individual inspections will not relieve the...

  15. 49 CFR 451.13 - Action by approval authority-approval by design type.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) COAST GUARD, DEPARTMENT OF HOMELAND SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of New Containers § 451.13 Action by approval authority-approval by design type. (a) The... of safety approval plates to the containers. Absence of individual inspections will not relieve the...

  16. 49 CFR 451.13 - Action by approval authority-approval by design type.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) COAST GUARD, DEPARTMENT OF HOMELAND SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of New Containers § 451.13 Action by approval authority-approval by design type. (a) The... of safety approval plates to the containers. Absence of individual inspections will not relieve the...

  17. Waste Isolation Pilot Plant Technical Assessment Team Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None, None

    This report provides the results of the Waste Isolation Pilot Plant (WIPP) technical assessment led by the Savannah River National Laboratory and conducted by a team of experts in pertinent disciplines from SRNL and Lawrence Livermore National Laboratory (LLNL), Oak Ridge National Laboratory (ORNL), Pacific Northwest National Laboratory (PNNL), and Sandia National Laboratories (SNL).

  18. Capturing Energy-Saving Opportunities: Improving Building Efficiency in Rajasthan through Energy Code Implementation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tan, Qing; Yu, Sha; Evans, Meredydd

    2016-05-01

    India adopted the Energy Conservation Building Code (ECBC) in 2007. Rajasthan is the first state to make ECBC mandatory at the state level. In collaboration with Malaviya National Institute of Technology (MNIT) Jaipur, Pacific Northwest National Laboratory (PNNL) has been working with Rajasthan to facilitate the implementation of ECBC. This report summarizes milestones made in Rajasthan and PNNL's contribution in institutional set-ups, capacity building, compliance enforcement and pilot building construction.

  19. 2007 Annual Report Summer Research Institute Interfacial and Condensed Phase Chemical Physics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beck, Kenneth M.

    2007-10-31

    The Pacific Northwest National Laboratory (PNNL) hosted its fourth annual Summer Research Institute in Interfacial and Condensed Phase Chemical Physics from April through September 2007. During this time, 21 PNNL scientists hosted 23 participants from 20 different universities. Of the 23 participants, 20 were graduate students, 1 was a postdoctoral fellow, and 2 were university faculty members. This report covers the essense of the program and the research the participants performed.

  20. 75 FR 70936 - Accreditation and Approval of Inspectorate America Corporation, as a Commercial Gauger and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-19

    ... laboratories. http:[sol][sol]cbp.gov[sol]xp[sol]cgov[sol]import[sol]operations-- support[sol]labs--scientific--svcs[sol]commercial--gaugers[sol]. DATES: The accreditation and approval of Inspectorate America...

  1. 75 FR 70935 - Accreditation and Approval of Inspectorate America Corporation, as a Commercial Gauger and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-19

    ... laboratories. http:[sol][sol]cbp.gov[sol]xp[sol]cgov[sol]import[sol]operations-- support[sol]labs--scientific--svcs[sol]commercial--gaugers[sol]. DATES: The accreditation and approval of Inspectorate America...

  2. 76 FR 64964 - Re-Accreditation and Re-Approval of SGS North America, Inc. as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-19

    ... DEPARTMENT OF HOMELAND SECURITY Bureau of Customs and Border Protection Re-Accreditation and Re... Border Protection, Department of Homeland Security. ACTION: Notice of re-approval of SGS North America..., pursuant to 19 CFR 151.13, SGS North America, Inc., Bayonne, New Jersey 07002, has been re-approved to...

  3. The stem cell laboratory: design, equipment, and oversight.

    PubMed

    Wesselschmidt, Robin L; Schwartz, Philip H

    2011-01-01

    This chapter describes some of the major issues to be considered when setting up a laboratory for the culture of human pluripotent stem cells (hPSCs). The process of establishing a hPSC laboratory can be divided into two equally important parts. One is completely administrative and includes developing protocols, seeking approval, and establishing reporting processes and documentation. The other part of establishing a hPSC laboratory involves the physical plant and includes design, equipment and personnel. Proper planning of laboratory operations and proper design of the physical layout of the stem cell laboratory so that meets the scope of planned operations is a major undertaking, but the time spent upfront will pay long-term returns in operational efficiency and effectiveness. A well-planned, organized, and properly equipped laboratory supports research activities by increasing efficiency and reducing lost time and wasted resources.

  4. PNNL researcher explores behavior of complex molecules

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Manke, Kristin L.

    2007-11-19

    From cold winters in St. Petersburg, Russia, to sweltering summers in southeastern Washington State, Dr. Julia Laskin’s career in science has been an interesting journey. Her latest trip landed her on the steps of the White House for a photo-op with the President. Laskin received the Presidential Early Career Award for Scientists and Engineers for her research on the fundamental aspects of the reaction kinetics and dynamics of activating and dissociating complex molecular ions. Her work at Pacific Northwest National Laboratory provides a basis for the development of analytical techniques for improved characterization of synthetic and natural polymers, petroleum, biofuelsmore » and other complex samples using mass spectrometry.« less

  5. Assessment of Cable Aging Equipment, Status of Acquired Materials, and Experimental Matrix at the Pacific Northwest National Laboratory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fifield, Leonard S.; Westman, Matthew P.; Zwoster, Andy

    2015-03-30

    The need for increased understanding of the aging and degradation behavior for polymer components of nuclear power plant electrical cables is described in this report. The highest priority materials for study and the resources available at PNNL for these studies are also described. The anticipated outcomes of the PNNL work described are : improved understanding of appropriate accelerated aging conditions, improved knowledge of correlation between observable aging indicators and cable condition in support of advanced non-destructive evaluation methods, and practical knowledge of condition-based cable lifetime prediction.

  6. Milestone Report - Complete New Adsorbent Materials for Marine Testing to Demonstrate 4.5 g-U/kg Adsorbent

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Janke, Christopher James; Das, Sadananda; Oyola, Yatsandra

    2014-08-01

    This report describes work on the successful completion of Milestone M2FT-14OR03100115 (8/20/2014) entitled, “Complete new adsorbent materials for marine testing to demonstrate 4.5 g-U/kg adsorbent”. This effort is part of the Seawater Uranium Recovery Program, sponsored by the U.S. Department of Energy, Office of Nuclear Energy, and involved the development of new adsorbent materials at the Oak Ridge National Laboratory (ORNL) and marine testing at the Pacific Northwest National Laboratory (PNNL). ORNL has recently developed two new families of fiber adsorbents that have demonstrated uranium adsorption capacities greater than 4.5 g-U/kg adsorbent after marine testing at PNNL. One adsorbent wasmore » synthesized by radiation-induced graft polymerization of itaconic acid and acrylonitrile onto high surface area polyethylene fibers followed by amidoximation and base conditioning. This fiber showed a capacity of 4.6 g-U/kg adsorbent in marine testing at PNNL. The second adsorbent was prepared by atom-transfer radical polymerization of t-butyl acrylate and acrylonitrile onto halide-functionalized round fibers followed by amidoximation and base hydrolysis. This fiber demonstrated uranium adsorption capacity of 5.4 g-U/kg adsorbent in marine testing at PNNL.« less

  7. Pretreatment Engineering Platform Phase 1 Final Test Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kurath, Dean E.; Hanson, Brady D.; Minette, Michael J.

    2009-12-23

    Pacific Northwest National Laboratory (PNNL) was tasked by Bechtel National Inc. (BNI) on the River Protection Project, Hanford Tank Waste Treatment and Immobilization Plant (RPP-WTP) project to conduct testing to demonstrate the performance of the WTP Pretreatment Facility (PTF) leaching and ultrafiltration processes at an engineering-scale. In addition to the demonstration, the testing was to address specific technical issues identified in Issue Response Plan for Implementation of External Flowsheet Review Team (EFRT) Recommendations - M12, Undemonstrated Leaching Processes.( ) Testing was conducted in a 1/4.5-scale mock-up of the PTF ultrafiltration system, the Pretreatment Engineering Platform (PEP). Parallel laboratory testing wasmore » conducted in various PNNL laboratories to allow direct comparison of process performance at an engineering-scale and a laboratory-scale. This report presents and discusses the results of those tests.« less

  8. TSO C-129 approvals and anticipated approvals

    DOT National Transportation Integrated Search

    2001-01-01

    This document contains a table of the approvals and anticipated approvals of TSO-C129a equipment (the technical standard order (TSO) for Airborne Supplemental Navigation Equipment Using the Global Positioning System (GPS)). This TSO prescribes the mi...

  9. Systems Approach to Defeating Maritime Improvised Explosive Devices in U.S. Ports

    DTIC Science & Technology

    2008-12-01

    DETECTION Pfi PROBABILITY OF FALSE IDENTIFICATION PHPK PROBABILITY OF HIT/PROBABILITY OF KILL PMA POST MISSION ANALYSIS PNNL PACIFIC...16 Naval Warfare Publication 27-2(Rev. B), Section 1.8.4.1(unclassified) 42 detection analysis is conducted...NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA Approved for public release; distribution is unlimited Prepared

  10. Sulfur Solubility Testing and Characterization of LAW Phase 1 Matrix Glasses

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fox, K.

    In this report, the Savannah River National Laboratory (SRNL) provides chemical analysis results for a series of simulated low-activity waste (LAW) glass compositions. These data will be used in the development of improved sulfur solubility models for LAW glass. A procedure developed at Pacific Northwest National Laboratory (PNNL) for producing sulfur saturated melts (SSMs) was carried out at both SRNL and PNNL to fabricate the glasses characterized in this report. This method includes triplicate melting steps with excess sodium sulfate, followed by grinding and washing to remove unincorporated sulfur salts. The wash solutions were also analyzed as part of thismore » study.« less

  11. Improvement of capabilities of the Distributed Electrochemistry Modeling Tool for investigating SOFC long term performance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gonzalez Galdamez, Rinaldo A.; Recknagle, Kurtis P.

    2012-04-30

    This report provides an overview of the work performed for Solid Oxide Fuel Cell (SOFC) modeling during the 2012 Winter/Spring Science Undergraduate Laboratory Internship at Pacific Northwest National Laboratory (PNNL). A brief introduction on the concept, operation basics and applications of fuel cells is given for the general audience. Further details are given regarding the modifications and improvements of the Distributed Electrochemistry (DEC) Modeling tool developed by PNNL engineers to model SOFC long term performance. Within this analysis, a literature review on anode degradation mechanisms is explained and future plans of implementing these into the DEC modeling tool are alsomore » proposed.« less

  12. CPTAC Team Releases Targeted Proteomic Assays for Ovarian Cancer | Office of Cancer Clinical Proteomics Research

    Cancer.gov

    Pacific Northwest National Laboratory (PNNL) investigators in the Clinical Proteomic Tumor Analysis Consortium (CPTAC) of the National Cancer Institute (NCI), announces the public release of 98 targeted mass spectrometry-based assays for ovarian cancer research studies.  Chosen based on proteogenomic observations from the recently published multi-institutional collaborative project between PNNL and Johns Hopkins University that comprehensively examined the collections of proteins in the tumors of ovarian cancer patients (highlighted in a paper in

  13. Wide Area Recovery and Resiliency Program (WARRP) Knowledge Enhancement Events: CBR Workshop After Action Report

    DTIC Science & Technology

    2012-01-01

    Laboratories Walker Ray Walker Engineering Solutions, LLC Williams Patricia Denver Office of Emergency Management Wood- Zika Annmarie Lawrence Livermore...llnl.gov AnnMarie Wood- Zika woodzika1@llnl.gov Pacific Northwest National Laboratory Ann Lesperance ann.lesperance@pnnl.gov Jessica Sandusky

  14. Undergraduate Organic Chemistry Laboratory Safety

    NASA Astrophysics Data System (ADS)

    Luckenbaugh, Raymond W.

    1996-11-01

    Each organic chemistry student should become familiar with the educational and governmental laboratory safety requirements. One method for teaching laboratory safety is to assign each student to locate safety resources for a specific class laboratory experiment. The student should obtain toxicity and hazardous information for all chemicals used or produced during the assigned experiment. For example, what is the LD50 or LC50 for each chemical? Are there any specific hazards for these chemicals, carcinogen, mutagen, teratogen, neurotixin, chronic toxin, corrosive, flammable, or explosive agent? The school's "Chemical Hygiene Plan", "Prudent Practices for Handling Hazardous Chemicals in the Laboratory" (National Academy Press), and "Laboratory Standards, Part 1910 - Occupational Safety and Health Standards" (Fed. Register 1/31/90, 55, 3227-3335) should be reviewed for laboratory safety requirements for the assigned experiment. For example, what are the procedures for safe handling of vacuum systems, if a vacuum distillation is used in the assigned experiment? The literature survey must be submitted to the laboratory instructor one week prior to the laboratory session for review and approval. The student should then give a short presentation to the class on the chemicals' toxicity and hazards and describe the safety precautions that must be followed. This procedure gives the student first-hand knowledge on how to find and evaluate information to meet laboartory safety requirements.

  15. The Stem Cell Laboratory: Design, Equipment, and Oversight

    PubMed Central

    Wesselschmidt, Robin L.; Schwartz, Philip H.

    2013-01-01

    This chapter describes some of the major issues to be considered when setting up a laboratory for the culture of human pluripotent stem cells (hPSCs). The process of establishing a hPSC laboratory can be divided into two equally important parts. One is completely administrative and includes developing protocols, seeking approval, and establishing reporting processes and documentation. The other part of establishing a hPSC laboratory involves the physical plant and includes design, equipment and personnel. Proper planning of laboratory operations and proper design of the physical layout of the stem cell laboratory so that meets the scope of planned operations is a major undertaking, but the time spent upfront will pay long-term returns in operational efficiency and effectiveness. A well-planned, organized, and properly equipped laboratory supports research activities by increasing efficiency and reducing lost time and wasted resources. PMID:21822863

  16. The Pathology Laboratory Act 2007 explained.

    PubMed

    Looi, Lai-Meng

    2008-06-01

    The past century has seen tremendous changes in the scope and practice of pathology laboratories in tandem with the development of the medical services in Malaysia. Major progress was made in the areas of training and specialization of pathologists and laboratory technical staff. Today the pathology laboratory services have entered the International arena, and are propelled along the wave of globalization. Many new challenges have emerged as have new players in the field. Landmark developments over the past decade include the establishment of national quality assurance programmes, the mushrooming of private pathology laboratories, the establishment of a National Accreditation Standard for medical testing laboratories based on ISO 15189, and the passing of the Pathology Laboratory Act in Parliament in mid-2007. The Pathology Laboratory Act 2007 seeks to ensure that the pathology laboratory is accountable to the public, meets required standards of practice, participates in Quality Assurance programmes, is run by qualified staff, complies with safety requirements and is subject to continuous audit. The Act is applicable to all private laboratories (stand alone or hospital) and laboratories in statutory bodies (Universities, foundations). It is not applicable to public laboratories (established and operated by the government) and side-room laboratories established in clinics of registered medical or dental practitioners for their own patients (tests as in the First and Second Schedules respectively). Tests of the Third Schedule (home test blood glucose, urine glucose, urine pregnancy test) are also exempted. The Act has 13 Parts and provides for control of the pathology laboratory through approval (to establish and maintain) and licensing (to operate or provide). The approval or license may only be issued to a sole proprietor, partnership or body corporate, and then only if the entity includes a registered medical practitioner. Details of personnel qualifications and

  17. 75 FR 39549 - Accreditation and Approval of Intertek USA, Inc., as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-09

    ... 151.13, Intertek USA, Inc., 1000 Port Carteret Drive Building C, Carteret, NJ 07008, has been approved to gauge and accredited to test petroleum and petroleum products for customs purposes, in accordance...

  18. 75 FR 70936 - Accreditation and Approval of Intertek USA, Inc., as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-19

    .... http:[sol][sol]cbp.gov[sol]xp[sol]cgov[sol]import[sol]operations-- support[sol]labs--scientific--svcs[sol]commercial--gaugers[sol] DATES: The accreditation and approval of Intertek USA, Inc., as...

  19. External quality assessment for CD4 + T-lymphocyte count test: Performance of the Brazilian public health laboratories network.

    PubMed

    Gaspar, Pâmela Cristina; Wohlke, Bruna Lovizutto Protti; Brunialti, Milena Karina Coló; Pires, Ana Flávia; Kohiyama, Igor Massaki; Salomão, Reinaldo; Alonso Neto, José Boullosa; Júnior, Orlando da Costa Ferreira; Franchini, Miriam; Bazzo, Maria Luiza; Benzaken, Adele Schwartz

    2018-05-01

    The National Network for CD4+ T-lymphocyte counting of Brazil comprises 93 laboratories. This study reports the laboratory performances achieved in external quality assessment (EQA) rounds provides by Ministry of Health to evaluate the quality of the kits used and the performance of test by the technicians.Ten EQA rounds were analyzed according the EQA criteria aimed to evaluate individual laboratory performance on the basis of the accuracy of their results compared to the general mean obtained by all participating laboratories and the reproducibility of the results obtained between 2 samples from the same donor.The percentage of approved and failed laboratories in the EQAs tends to follow a uniform pattern. Since 2011, approval has remained above 80% and the failure rate has never exceeded 15%.EQA is very important to evaluate the performance of the laboratories, to identify monitor, and to resolve errors as quickly as possible.

  20. PNNL Researchers Collect Permafrost Cores in Alaska

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2016-11-23

    Permafrost is ground that is frozen for two or more years. In the Arctic, discontinuous regions of this saturated admixture of soil and rock store a large fraction of the Earth’s carbon – about 1672 petagrams (1672 trillion kilograms). As temperatures increase in the Northern Hemisphere, a lot of that carbon may be released to the atmosphere, making permafrost an important factor to represent accurately in global climate models. At Pacific Northwest National Laboratory, a group led by James C. Stegen periodically extracts permafrost core samples from a site near Fairbanks, Alaska. Back at the lab in southeastern Washington State,more » they study the cores for levels of microbial activity, carbon fluxes, hydrologic patterns, and other factors that reveal the dynamics of this consequential layer of soil and rock.« less

  1. Initial Characterization of Unequal-Length, Low-Background Proportional Counters for Absolute Gas-Counting Applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mace, Emily K.; Aalseth, Craig E.; Bonicalzi, Ricco

    Abstract. Characterization of two sets of custom unequal length proportional counters is underway at Pacific Northwest National Laboratory (PNNL). These detectors will be used in measurements to determine the absolute activity concentration of gaseous radionuclides (e.g., 37Ar). A set of three detectors has been fabricated based on previous PNNL ultra-low-background proportional counters (ULBPC) designs and now operate in PNNL’s shallow underground counting laboratory. A second set of four counters has also been fabricated using clean assembly of OFHC copper components for use in an above-ground counting laboratory. Characterization of both sets of detectors is underway with measurements of background rates,more » gas gain, energy resolution, and shielding considerations. These results will be presented along with uncertainty estimates of future absolute gas counting measurements.« less

  2. 76 FR 59769 - Clarification on the Division 1.1 Fireworks Approvals Policy

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-27

    ... test laboratory if the firework device is manufactured in accordance with APA Standard 87-1 (IBR, see... certify that the firework device conforms to the APA Standard 87-1 and that the descriptions and technical... issuing the EX approval. While APA Standard 87-1 references two instances where Division 1.1 fireworks may...

  3. 76 FR 64963 - Accreditation and Approval of Intertek USA, Inc., as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-19

    ... 151.13, Intertek USA, Inc., Carr. 28, Km 2.0, Ind. Park Luchetti, Bayamon, PR 00960, has been approved... to [email protected] . Please reference the Web site listed below for a complete listing of CBP...

  4. Adaption of Machine Fluid Analysis for Manufacturing - Final Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pardini, Allan F.

    2005-08-16

    Pacific Northwest National Laboratory (PNNL: Operated by Battelle Memorial Institute for the Department of Energy) is working with the Department of Energy (DOE) to develop technology for the US mining industry. Filtration and lubricant suppliers to the pulp and paper industry had noted the recent accomplishments by PNNL and its industrial partners in the DOE OIT Mining Industry of the Future Program, and asked for assistance in adapting this DOE-funded technology to the pulp and paper industry.

  5. 30 CFR 28.20 - Certificates of approval; scope of approval.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Certificates of approval; scope of approval. 28.20 Section 28.20 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS FUSES FOR USE WITH DIRECT CURRENT IN PROVIDING SHORT-CIRCUIT...

  6. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barrett, Christopher A.; Martinez, Alonzo; McNamara, Bruce K.

    International Atom Energy Agency (IAEA) safeguard verification measures in gaseous centrifuge enrichment plants (GCEPs) rely on environmental sampling, non-destructive assay (NDA), and destructive assay (DA) sampling and analysis to determine uranium enrichment. UF6 bias defect measurements are made by DA sampling and analysis to assure that enrichment is consistent with declarations. DA samples are collected from a limited number of cylinders for high precision, offsite mass spectrometer analysis. Samples are typically drawn from a sampling tap into a UF6 sample bottle, then packaged, sealed, and shipped under IAEA chain of custody to an offsite analytical laboratory. Future DA safeguard measuresmore » may require improvements in efficiency and effectiveness as GCEP capacities increase and UF6 shipping regulations become increasingly more restrictive. The Pacific Northwest National Laboratory (PNNL) DA sampler concept and Laser Ablation Absorption Ratio Spectrometry (LAARS) assay method are under development to potentially provide DA safeguard tools that increase inspection effectiveness and reduce sample shipping constraints. The PNNL DA sampler concept uses a handheld sampler to collect DA samples for either onsite LAARS assay or offsite laboratory analysis. The DA sampler design will use a small sampling planchet that is coated with an adsorptive film to collect controlled quantities of UF6 gas directly from a cylinder or process sampling tap. Development efforts are currently underway at PNNL to enhance LAARS assay performance to allow high-precision onsite bias defect measurements. In this paper, we report on the experimental investigation to develop adsorptive films for the PNNL DA sampler concept. These films are intended to efficiently capture UF6 and then stabilize the collected DA sample prior to onsite LAARS or offsite laboratory analysis. Several porous material composite films were investigated, including a film designed to maximize the chemical

  7. 30 CFR 746.14 - Approval, disapproval or conditional approval, of mining plan.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., of mining plan. 746.14 Section 746.14 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR FEDERAL LANDS PROGRAM REVIEW AND APPROVAL OF MINING PLANS § 746.14 Approval, disapproval or conditional approval, of mining plan. The Secretary shall approve, disapprove or...

  8. PNNL pushing scientific discovery through data intensive computing breakthroughs

    ScienceCinema

    Deborah Gracio; David Koppenaal; Ruby Leung

    2018-05-18

    The Pacific Northwest National Laboratory's approach to data intensive computing (DIC) is focused on three key research areas: hybrid hardware architectures, software architectures, and analytic algorithms. Advancements in these areas will help to address, and solve, DIC issues associated with capturing, managing, analyzing and understanding, in near real time, data at volumes and rates that push the frontiers of current technologies.

  9. Sulfur Solubility Testing and Characterization of Hanford LAW Phase 2, Inner Layer Matrix Glasses

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fox, K. M.; Edwards, T. B.; Caldwell, M. E.

    In this report, the Savannah River National Laboratory (SRNL) provides chemical analyses and Product Consistency Test (PCT) results for a series of simulated low activity waste (LAW) glass compositions. A procedure developed at the Pacific Northwest National Laboratory (PNNL) for producing sulfur saturated melts (SSMs) was carried out at both SRNL and PNNL to fabricate the glasses characterized in this report. This method includes triplicate melting steps with excess sodium sulfate, followed by grinding and washing to remove unincorporated sulfur salts. The wash solutions were also analyzed as part of this study. These data will be used in the developmentmore » of improved sulfur solubility models for LAW glass.« less

  10. Characterization of Offgas Generated During Calcination of Incinerator Ash Surrogates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wigent, H.L.; Vienna, J.D.; Darab, J.G.

    1999-01-28

    The Pacific Northwest National Laboratory (PNNL), in cooperation with the Los Alamos National Laboratory (LANL) and Safe Sites of Colorado (SSOC), developed a recommended flowsheet for the processing of plutonium-bearing incinerator ash stored at the Rocky Flats Environmental Technology Site (RFETS) (Lucy et al. 1998). This flowsheet involves a calcination pretreatment step, the purpose of which is to remove carbonaceous material from the incinerator ash. Removal of this material reduced the probability of process upsets, improved product quality, and increases ash waste loading. As part of the continued development of the recommended flowsheet, PNNL performed a series of tests tomore » characterize the offgas generated during the calcination process.« less

  11. Measurement and Analysis Plan for Investigation of Spent-Fuel Assay Using Lead Slowing-Down Spectroscopy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smith, Leon E.; Haas, Derek A.; Gavron, Victor A.

    2009-09-25

    Under funding from the Department of Energy Office of Nuclear Energy’s Materials, Protection, Accounting, and Control for Transmutation (MPACT) program (formerly the Advanced Fuel Cycle Initiative Safeguards Campaign), Pacific Northwest National Laboratory (PNNL) and Los Alamos National Laboratory (LANL) are collaborating to study the viability of lead slowing-down spectroscopy (LSDS) for spent-fuel assay. Based on the results of previous simulation studies conducted by PNNL and LANL to estimate potential LSDS performance, a more comprehensive study of LSDS viability has been defined. That study includes benchmarking measurements, development and testing of key enabling instrumentation, and continued study of time-spectra analysis methods.more » This report satisfies the requirements for a PNNL/LANL deliverable that describes the objectives, plans and contributing organizations for a comprehensive three-year study of LSDS for spent-fuel assay. This deliverable was generated largely during the LSDS workshop held on August 25-26, 2009 at Rensselaer Polytechnic Institute (RPI). The workshop itself was a prominent milestone in the FY09 MPACT project and is also described within this report.« less

  12. A Drop in the Bucket or a Pebble in a Pond: Commercial Building Partners’ Replication of EEMs Across Their Portfolios

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Antonopoulos, Chrissi A.; Baechler, Michael C.; Dillon, Heather E.

    This study presents findings from questionnaire and interview data investigating replication efforts of Commercial Building Partnership (CBP) partners that worked directly with the Pacific Northwest National Laboratory (PNNL). PNNL partnered with 12 organizations on new and retrofit construction projects as part of the U.S. Department of Energy (DOE) CBP program. PNNL and other national laboratories collaborate with industry leaders that own large portfolios of buildings to develop high performance projects for new construction and renovation. This project accelerates market adoption of commercially available energy saving technologies into the design process for new and upgraded commercial buildings. The labs provide assistancemore » to the partners’ design teams and make a business case for energy investments. From the owner’s perspective, a sound investment results in energy savings based on corporate objectives and design. Through a feedback questionnaire, along with personal interviews, PNNL gathered qualitative and quantitative information relating to replication efforts by each organization. Data through this process were analyzed to provide insight into two primary research areas: 1) CBP partners’ replication efforts of technologies and approaches used in the CBP project to the rest of the organization’s building portfolio (including replication verification), and, 2) the market potential for technology diffusion into the total U.S. commercial building stock, as a direct result of the CBP entire program.« less

  13. Impact of zeolite aging in hot liquid water on activity for acid-catalyzed dehydration of alcohols

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vjunov, Aleksei; Derewinski, Miroslaw A.; Fulton, John L.

    The catalytic performance of zeolite in aqueous medium depends on a multitude of factors, such as the concentration and distribution of active sites and framework integrity. Al K–edge extended X–ray absorption fine structure and 27Al MAS NMR spectroscopies in combination with DFT calculations are used to determine the distribution of tetrahedral Al sites both qualitatively and quantitatively for both parent and 48 h 160 ºC water treated HBEA catalysts. There is no evidence of Al coordination modification after aging in water. The distribution and concentration of Al T–sites, active centers for the dehydration of cyclohexanol, do not markedly impact themore » catalytic performance in water, because the Brønsted acidic protons are present in the form of hydrated hydronium ions and thus have very similar acid properties. The results suggest that all Brønsted acid sites are equally active in aqueous medium. The decrease of zeolite catalytic performance after water treatment is attributed to the reduced concentration of Brønsted acid sites. Increasing the stability of pore walls and decreasing the rate of Si–O–Si group hydrolysis may result in improved apparent zeolite catalytic performance in aqueous medium. Authors thank B. W. Arey (PNNL) for HIM measurements, T. Huthwelker for support during Al XAFS measurements at the Swiss Light Source (PSI, Switzerland), J. Z. Hu and S. D. Burton (PNNL) for support during NMR experiments. This work was supported by the U. S. Department of Energy (DOE), Office of Science, Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences & Biosciences. MD acknowledges support by the Materials Synthesis and Simulation Across Scales (MS3 Initiative) conducted under Laboratory Directed Research & Development Program at PNNL. HIM imaging and NMR experiments were performed at the Environmental Molecular Sciences Laboratory, a national scientific user facility sponsored by the DOE Office of Science, Office of

  14. The Subsurface Flow and Transport Laboratory: A New Department of Energy User's Facility for Intermediate-Scale Experimentation

    NASA Astrophysics Data System (ADS)

    Wietsma, T. W.; Oostrom, M.; Foster, N. S.

    2003-12-01

    Intermediate-scale experiments (ISEs) for flow and transport are a valuable tool for simulating subsurface features and conditions encountered in the field at government and private sites. ISEs offer the ability to study, under controlled laboratory conditions, complicated processes characteristic of mixed wastes and heterogeneous subsurface environments, in multiple dimensions and at different scales. ISEs may, therefore, result in major cost savings if employed prior to field studies. A distinct advantage of ISEs is that researchers can design physical and/or chemical heterogeneities in the porous media matrix that better approximate natural field conditions and therefore address research questions that contain the additional complexity of processes often encountered in the natural environment. A new Subsurface Flow and Transport Laboratory (SFTL) has been developed for ISE users in the Environmental Spectroscopy & Biogeochemistry Facility in the Environmental Molecular Sciences Laboratory (EMSL) at Pacific Northwest National Laboratory (PNNL). The SFTL offers a variety of columns and flow cells, a new state-of-the-art dual-energy gamma system, a fully automated saturation-pressure apparatus, and analytical equipment for sample processing. The new facility, including qualified staff, is available for scientists interested in collaboration on conducting high-quality flow and transport experiments, including contaminant remediation. Close linkages exist between the SFTL and numerical modelers to aid in experimental design and interpretation. This presentation will discuss the facility and outline the procedures required to submit a proposal to use this unique facility for research purposes. The W. R. Wiley Environmental Molecular Sciences Laboratory, a national scientific user facility, is sponsored by the U.S. Department of Energy's Office of Biological and Environmental Research and located at Pacific Northwest National Laboratory.

  15. 76 FR 50488 - Accreditation and Approval of Saybolt, LP., as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-15

    ... and 19 CFR 151.13, Saybolt, LP, Road 127 KM 13.4 Bo. Magas Arriba, P.R., has been approved to gauge...) 344-1060. The inquiry may also be sent to [email protected] . Please reference the Web site listed... Protection, 1300 Pennsylvania Avenue, NW., Suite 1500N, Washington, DC 20229, 202-344- 1060. [[Page 50489...

  16. Rolling Process Modeling Report. Finite-Element Model Validation and Parametric Study on various Rolling Process parameters

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Soulami, Ayoub; Lavender, Curt A.; Paxton, Dean M.

    2015-06-15

    Pacific Northwest National Laboratory (PNNL) has been investigating manufacturing processes for the uranium-10% molybdenum alloy plate-type fuel for high-performance research reactors in the United States. This work supports the U.S. Department of Energy National Nuclear Security Administration’s Office of Material Management and Minimization Reactor Conversion Program. This report documents modeling results of PNNL’s efforts to perform finite-element simulations to predict roll-separating forces for various rolling mill geometries for PNNL, Babcock & Wilcox Co., Y-12 National Security Complex, Los Alamos National Laboratory, and Idaho National Laboratory. The model developed and presented in a previous report has been subjected to further validationmore » study using new sets of experimental data generated from a rolling mill at PNNL. Simulation results of both hot rolling and cold rolling of uranium-10% molybdenum coupons have been compared with experimental results. The model was used to predict roll-separating forces at different temperatures and reductions for five rolling mills within the National Nuclear Security Administration Fuel Fabrication Capability project. This report also presents initial results of a finite-element model microstructure-based approach to study the surface roughness at the interface between zirconium and uranium-10% molybdenum.« less

  17. Statistical Methods and Tools for Uxo Characterization (SERDP Final Technical Report)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pulsipher, Brent A.; Gilbert, Richard O.; Wilson, John E.

    2004-11-15

    The Strategic Environmental Research and Development Program (SERDP) issued a statement of need for FY01 titled Statistical Sampling for Unexploded Ordnance (UXO) Site Characterization that solicited proposals to develop statistically valid sampling protocols for cost-effective, practical, and reliable investigation of sites contaminated with UXO; protocols that could be validated through subsequent field demonstrations. The SERDP goal was the development of a sampling strategy for which a fraction of the site is initially surveyed by geophysical detectors to confidently identify clean areas and subsections (target areas, TAs) that had elevated densities of anomalous geophysical detector readings that could indicate the presencemore » of UXO. More detailed surveys could then be conducted to search the identified TAs for UXO. SERDP funded three projects: those proposed by the Pacific Northwest National Laboratory (PNNL) (SERDP Project No. UXO 1199), Sandia National Laboratory (SNL), and Oak Ridge National Laboratory (ORNL). The projects were closely coordinated to minimize duplication of effort and facilitate use of shared algorithms where feasible. This final report for PNNL Project 1199 describes the methods developed by PNNL to address SERDP's statement-of-need for the development of statistically-based geophysical survey methods for sites where 100% surveys are unattainable or cost prohibitive.« less

  18. 75 FR 80061 - Abbott Laboratories, Inc.; Withdrawal of Approval of a New Drug Application for MERIDIA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-21

    ... withdrawing approval of a new drug application (NDA) for MERIDIA (sibutramine hydrochloride (HCl)) oral... requested that Abbott voluntarily withdraw MERIDIA (sibutramine HCl) oral capsules from the market, based on FDA's recent analysis of clinical trial data from the Sibutramine Cardiovascular Outcomes Trial (SCOUT...

  19. 38 CFR 17.65 - Approvals and provisional approvals of community residential care facilities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... approvals of community residential care facilities. 17.65 Section 17.65 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Community Residential Care § 17.65 Approvals and provisional approvals of community residential care facilities. (a) An approval of a facility meeting all of...

  20. Real-time Data Center Energy Efficiency At Pacific Northwest National Laboratory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sisk, Daniel R.; Khaleel, Mohammad A.; Marquez, Andres

    2009-05-26

    The escalating consumption of power in data centers worldwide has brought the issue of data center energy efficiency to the forefront. Data center owners and operators now regard detailed knowledge of the energy efficiencies of their data centers as a competitive advantage. With funding from the Department of Energy (NNSA), PNNL has undertaken an in-depth analysis of the real-time energy efficiency for its Energy Smart Data Center Test Bed(ESDC-TB), which is housed in the mixed-use EMSL. The analysis is centered around the real-time display of The Green Grid’s proposed DCiE metric. To calculate this metric, PNNL relies on a varietymore » of sources of data. At the ESDC-TB level, the data center is instrumented to the 100% level (all power consumption, and water temperatures and flow rates are measured). Most of this data is monitored in real-time, but the exception to this is with the CRAHs, which rely on a one-time power consumption measurement for the blowers (these are single speed blowers, so a one-time measurement suffices.). Outside of the data center (EMSL facility level), PNNL relies on the following: • Real-time data from the entire chiller plant (five chillers), six chilled water pumps, and one of four cooling towers (blowers only). • One-time power measurements for a single fixed speed pump that is representative of each grouping of pumps (the other pumps are assumed to possess the same power consumption levels). • One-time power measurements for a single two-speed cooling tower blower. This same blower model is deployed in three of the four cooling towers, so is assumed to be representative for all these blowers. • One-time power measurements for a single fixed speed cooling tower pump. This same pump model is deployed in all four cooling towers, so is assumed to be representative for all these pumps. A software tool named FRED was developed by PNNL to acquire, reduce, display, and archive all the data acquired from the ESDC-TB and EMSL

  1. Guidance for Human Subjects Research in the National Exposure Research Laboratory

    EPA Science Inventory

    This document provides guidance to investigators and managers associated with the U.S. Environmental Protection Agency (EPA) Office of Research and Development (ORD)’s National Exposure Research Laboratory (NERL) on the ethical conduct, regulatory review, and approval of all huma...

  2. 42 CFR 488.61 - Special procedures for approval and re-approval of organ transplant centers.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Approval. Centers that have lost their Medicare approval may seek re-entry into the Medicare program at any... 42 Public Health 5 2012-10-01 2012-10-01 false Special procedures for approval and re-approval of... ENFORCEMENT PROCEDURES Special Requirements § 488.61 Special procedures for approval and re-approval of organ...

  3. 42 CFR 488.61 - Special procedures for approval and re-approval of organ transplant centers.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Approval. Centers that have lost their Medicare approval may seek re-entry into the Medicare program at any... 42 Public Health 5 2011-10-01 2011-10-01 false Special procedures for approval and re-approval of... ENFORCEMENT PROCEDURES Special Requirements § 488.61 Special procedures for approval and re-approval of organ...

  4. 42 CFR 488.61 - Special procedures for approval and re-approval of organ transplant centers.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Approval. Centers that have lost their Medicare approval may seek re-entry into the Medicare program at any... 42 Public Health 5 2013-10-01 2013-10-01 false Special procedures for approval and re-approval of... ENFORCEMENT PROCEDURES Special Requirements § 488.61 Special procedures for approval and re-approval of organ...

  5. 42 CFR 488.61 - Special procedures for approval and re-approval of organ transplant centers.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Approval. Centers that have lost their Medicare approval may seek re-entry into the Medicare program at any... 42 Public Health 5 2010-10-01 2010-10-01 false Special procedures for approval and re-approval of... ENFORCEMENT PROCEDURES Special Requirements § 488.61 Special procedures for approval and re-approval of organ...

  6. 77 FR 12866 - Accreditation and Approval of Certispec Services USA, Inc., as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-02

    ... 77590, has been approved to gauge and accredited to test petroleum and petroleum products, organic chemicals and vegetable oils for customs purposes, in accordance with the provisions of 19 CFR 151.12 and 19...

  7. 78 FR 18362 - Accreditation and Approval of Amspec Services, LLC, as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-26

    ... petroleum products, organic chemicals and vegetable oils for customs purposes, in accordance with the... Services, LLC, has been approved to gauge and accredited to test petroleum and petroleum products, organic chemicals and vegetable oils for customs purposes for the next three years as of September 21, 2012. DATES...

  8. 77 FR 12865 - Accreditation and Approval of SGS North America, Inc., as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-02

    ..., VA 23602, has been approved to gauge and accredited to test petroleum and petroleum products, organic chemicals and vegetable oils for customs purposes, in accordance with the provisions of 19 CFR 151.12 and 19...

  9. 77 FR 47428 - Accreditation and Approval of SGS North America, Inc., as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-08

    ... approved to gauge and accredited to test petroleum and petroleum products, organic chemicals and vegetable oils for customs purposes, in accordance with the provisions of 19 CFR 151.12 and 19 CFR 151.13. Anyone...

  10. 42 CFR 493.807 - Condition: Reinstatement of laboratories performing nonwaived testing.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., subspecialties, analyte or test, or voluntarily withdraws its certification under CLIA for the failed specialty, subspecialty, or analyte, the laboratory must then demonstrate sustained satisfactory performance on two... reinstatement for certification and Medicare or Medicaid approval in that specialty, subspecialty, analyte or...

  11. 42 CFR 493.807 - Condition: Reinstatement of laboratories performing nonwaived testing.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., subspecialties, analyte or test, or voluntarily withdraws its certification under CLIA for the failed specialty, subspecialty, or analyte, the laboratory must then demonstrate sustained satisfactory performance on two... reinstatement for certification and Medicare or Medicaid approval in that specialty, subspecialty, analyte or...

  12. 42 CFR 493.807 - Condition: Reinstatement of laboratories performing nonwaived testing.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., subspecialties, analyte or test, or voluntarily withdraws its certification under CLIA for the failed specialty, subspecialty, or analyte, the laboratory must then demonstrate sustained satisfactory performance on two... reinstatement for certification and Medicare or Medicaid approval in that specialty, subspecialty, analyte or...

  13. 76 FR 23339 - Notice of Issuance of License Amendment Regarding Decommission Plan Approval; University of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-26

    ... NUCLEAR REGULATORY COMMISSION [Docket No. 50-113; NRC-2009-0549] Notice of Issuance of License Amendment Regarding Decommission Plan Approval; University of Arizona Research Reactor The U.S. Nuclear... located within the University of Arizona Nuclear Reactor Laboratory (NRL) on the 325-acre campus of the...

  14. 78 FR 66758 - Accreditation and Approval of AMSPEC Services, LLC, as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-06

    ... petroleum products, organic chemicals and vegetable oils for customs purposes for the next three years as of... 02149, has been approved to gauge and accredited to test petroleum and petroleum products, organic chemicals and vegetable oils for customs purposes, in accordance with the provisions of 19 CFR 151.12 and 19...

  15. 19 CFR 115.41 - Certificate of approval for containers approved after manufacture.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CARGO CONTAINER AND ROAD VEHICLE CERTIFICATION PURSUANT TO INTERNATIONAL CUSTOMS CONVENTIONS Procedures for Approval of Containers After Manufacture § 115... 19 Customs Duties 1 2011-04-01 2011-04-01 false Certificate of approval for containers approved...

  16. 19 CFR 115.41 - Certificate of approval for containers approved after manufacture.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CARGO CONTAINER AND ROAD VEHICLE CERTIFICATION PURSUANT TO INTERNATIONAL CUSTOMS CONVENTIONS Procedures for Approval of Containers After Manufacture § 115... 19 Customs Duties 1 2010-04-01 2010-04-01 false Certificate of approval for containers approved...

  17. 19 CFR 115.41 - Certificate of approval for containers approved after manufacture.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CARGO CONTAINER AND ROAD VEHICLE CERTIFICATION PURSUANT TO INTERNATIONAL CUSTOMS CONVENTIONS Procedures for Approval of Containers After Manufacture § 115... 19 Customs Duties 1 2012-04-01 2012-04-01 false Certificate of approval for containers approved...

  18. 19 CFR 115.41 - Certificate of approval for containers approved after manufacture.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CARGO CONTAINER AND ROAD VEHICLE CERTIFICATION PURSUANT TO INTERNATIONAL CUSTOMS CONVENTIONS Procedures for Approval of Containers After Manufacture § 115... 19 Customs Duties 1 2014-04-01 2014-04-01 false Certificate of approval for containers approved...

  19. 19 CFR 115.41 - Certificate of approval for containers approved after manufacture.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CARGO CONTAINER AND ROAD VEHICLE CERTIFICATION PURSUANT TO INTERNATIONAL CUSTOMS CONVENTIONS Procedures for Approval of Containers After Manufacture § 115... 19 Customs Duties 1 2013-04-01 2013-04-01 false Certificate of approval for containers approved...

  20. Automation of a Large Analytical Chemistry Laboratory

    DTIC Science & Technology

    1990-12-01

    Division Brooks Air Force Base , Texas 78235-5501 NOTICES When Government drawings, specifications, or other data are used for any purpose other than a...been reviewed and is approved for publication. Air Force installations may direct requests for copies of this report to: Air Force Occupational and...remaining for the analyses. Our laboratory serves worldwide Air Force installations and therefore comes up against these sample holding time requirements

  1. Towards adaptive, streaming analysis of x-ray tomography data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Thomas, Mathew; Kleese van Dam, Kerstin; Marshall, Matthew J.

    2015-03-04

    Temporal and spatial resolution of chemical imaging methodologies such as x-ray tomography are rapidly increasing, leading to more complex experimental procedures and fast growing data volumes. Automated analysis pipelines and big data analytics are becoming essential to effectively evaluate the results of such experiments. Offering those data techniques in an adaptive, streaming environment can further substantially improve the scientific discovery process, by enabling experimental control and steering based on the evaluation of emerging phenomena as they are observed by the experiment. Pacific Northwest National Laboratory (PNNL)’ Chemical Imaging Initiative (CII - http://imaging.pnnl.gov/ ) has worked since 2011 towards developing amore » framework that allows users to rapidly compose and customize high throughput experimental analysis pipelines for multiple instrument types. The framework, named ‘Rapid Experimental Analysis’ (REXAN) Framework [1], is based on the idea of reusable component libraries and utilizes the PNNL developed collaborative data management and analysis environment ‘Velo’, to provide a user friendly analysis and data management environment for experimental facilities. This article will, discuss the capabilities established for X-Ray tomography, discuss lessons learned, and provide an overview of our more recent work in the Analysis in Motion Initiative (AIM - http://aim.pnnl.gov/ ) at PNNL to provide REXAN capabilities in a streaming environment.« less

  2. 78 FR 17282 - Agency Information Collection Activities; Approval of a Currently Approved Information Collection...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-20

    ... Research and Information Technology and Chief Information Officer. [FR Doc. 2013-06361 Filed 3-19-13; 8:45...-0379] Agency Information Collection Activities; Approval of a Currently Approved Information Collection... March 1, 2013, concerning request for comments on the approval of a currently approved information...

  3. Nuclear Science User Facilities (NSUF) Monthly Report March 2015

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Soelberg, Renae

    Nuclear Science User Facilities (NSUF) Formerly: Advanced Test Reactor National Scientific User Facility (ATR NSUF) Monthly Report February 2015 Highlights; Jim Cole attended the OECD NEA Expert Group on Innovative Structural Materials meeting in Paris, France; Jim Lane and Doug Copsey of Writers Ink visited PNNL to prepare an article for the NSUF annual report; Brenden Heidrich briefed the Nuclear Energy Advisory Committee-Facilities Subcommittee on the Nuclear Energy Infrastructure Database project and provided them with custom reports for their upcoming visits to Argonne National Laboratory, Idaho National Laboratory, Oak Ridge National Laboratory and the Massachusetts Institute of Technology; and Universitymore » of California-Berkeley Principal Investigator Mehdi Balooch visited PNNL to observe measurements and help finalize plans for completing the desired suite of analyses. His visit was coordinated to coincide with the visit of Jim Lane and Doug Copsey.« less

  4. Business Case for Nonintrusive Load Monitoring

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Baechler, Michael C.; Hao, He

    This report explores how utilities, researchers, and consumers could benefit from a lower cost approach to submetering using non-intrusive load monitoring (NILM). NILM is a process of using data from a single point of monitoring, such as a utility smart meter, to provide an itemized accounting of end use energy consumption in residential and small commercial buildings. Pacific Northwest National Laboratory (PNNL) prepared this report for the Bonneville Power Administration (BPA). PNNL participated in an advisory group as part of a research project sponsored by the U.S. Department of Energy (DOE), the Bonneville Power Administration, and the State of Washington.more » The Electric Power Research Institute (EPRI) convened the advisory committee for two workshops held to identify ways in which NILM may be used. PNNL, on behalf of DOE, helped to cosponsor the first of these workshops. Results of an end-use monitoring study of a bank branch conducted by PNNL are also presented for purposes of illustrating the need for better data in energy savings modeling (DOE 2013a).« less

  5. Insights Gained from Ultrasonic Testing of Piping Welds Subjected to the Mechanical Stress Improvement Process

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Anderson, Michael T.; Cinson, Anthony D.; Crawford, Susan L.

    2010-12-01

    Pacific Northwest National Laboratory (PNNL) is assisting the United States Nuclear Regulatory Commission (NRC) in developing a position on the management of primary water stress corrosion cracking (PWSCC) in leak-before-break piping systems. Part of this involves determining whether inspections alone, or inspections plus mitigation, are needed. This work addresses the reliability of ultrasonic testing (UT) of cracks that have been mitigated by the mechanical stress improvement process (MSIP). The MSIP has been approved by the NRC (NUREG-0313) since 1986 and modifies residual stresses remaining after welding with compressive, or neutral, stresses near the inner diameter surface of the pipe. Thismore » compressive stress is thought to arrest existing cracks and inhibit new crack formation. To evaluate the effectiveness of the MSIP and the reliability of ultrasonic inspections, flaws were evaluated both before and after MSIP application. An initial investigation was based on data acquired from cracked areas in 325-mm-diameter piping at the Ignalina Nuclear Power Plant (INPP) in Lithuania. In a follow-on exercise, PNNL acquired and evaluated similar UT data from a dissimilar metal weld (DMW) specimen containing implanted thermal fatigue cracks. The DMW specimen is a carbon steel nozzle-to-safe end-to-stainless steel pipe section that simulates a pressurizer surge nozzle. The flaws were implanted in the nozzle-to-safe end Alloy 82/182 butter region. Results are presented on the effects of MSIP on specimen surfaces, and on UT flaw responses.« less

  6. FDA Approves Immunotherapy for a Cancer that Affects Infants and Children | Frederick National Laboratory for Cancer Research

    Cancer.gov

    The U.S. Food and Drug Administration (FDA) has approved dinutuximab (ch14.18) as an immunotherapy for neuroblastoma, a rare type of childhood cancer that offers poor prognosis for about half of the children who are affected.  The National Cancer In

  7. NATIONAL ENVIRONMENTAL LABORATORY ACCREDITATION CONFERENCE: CONSTITUTION, BYLAWS AND STANDARDS; APPROVED JUNE 2000

    EPA Science Inventory

    As Director of the Environmental Protection Agency's National Environmental
    Laboratory Accreditation Program (NELAP), I offer my sincere appreciation to the many individuals who worked on the 2000 revision of the NELAC standards. I would like to give special recognition to th...

  8. What Is Bibliometrics and Why Should You Care?

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McBurney, Melissa K.; Novak, Pamela L.

    When we help an author publish a book or journal article, is that the end of the job? Viewed in the aggregate, a company's publications represent one of its greatest business assets. Can professionals in the information and communication fields help their company understand the return on its investment in publishing? The field of bibliometrics studies publication patterns by using quantitative analysis and statistics. Bibliometrics can be either descriptive, such as looking at how many articles your organization has published, or evaluative, such as using citation analysis to look at how those articles influenced subsequent research by others. Counting publicationsmore » can be useful for doing some comparisons, but citation analysis allows you to look at the impact those articles have had on others by determining how often they are cited. Citation analysis can also show what journals, organizations, and even countries have high impact in different fields of research. The Institute for Scientific Information (ISI) has been a leader in the citation analysis field since 1961, when ISI published the first Science Citation Index. Pacific Northwest National Laboratory has been using data from ISI for both descriptive and evaluative purposes. This data is used to track what the researchers at the Laboratory are writing and then comparing research groups within the organization over a period of years to identify trends and opportunities. PNNL has also used citation analysis to explore what organizations and academic institutions are doing research in certain fields for partnering opportunities. We have realized that the electronic system PNNL uses to approve and track its publications contains very valuable bibliometric data that can be used to make decisions about business directions for the company.« less

  9. 19 CFR 151.73 - Importer's request for commercial laboratory test.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Hair § 151.73 Importer's request for commercial laboratory test. (a) Conditions for commercial test. If... request that a commercial test be made to determine the percentage clean yield of the wool or hair. (b... the wool or hair in dispute to be selected and tested by a commercial method approved by the...

  10. 19 CFR 151.73 - Importer's request for commercial laboratory test.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Hair § 151.73 Importer's request for commercial laboratory test. (a) Conditions for commercial test. If... request that a commercial test be made to determine the percentage clean yield of the wool or hair. (b... the wool or hair in dispute to be selected and tested by a commercial method approved by the...

  11. 19 CFR 151.73 - Importer's request for commercial laboratory test.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Hair § 151.73 Importer's request for commercial laboratory test. (a) Conditions for commercial test. If... request that a commercial test be made to determine the percentage clean yield of the wool or hair. (b... the wool or hair in dispute to be selected and tested by a commercial method approved by the...

  12. 19 CFR 151.73 - Importer's request for commercial laboratory test.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Hair § 151.73 Importer's request for commercial laboratory test. (a) Conditions for commercial test. If... request that a commercial test be made to determine the percentage clean yield of the wool or hair. (b... the wool or hair in dispute to be selected and tested by a commercial method approved by the...

  13. 19 CFR 151.73 - Importer's request for commercial laboratory test.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Hair § 151.73 Importer's request for commercial laboratory test. (a) Conditions for commercial test. If... request that a commercial test be made to determine the percentage clean yield of the wool or hair. (b... the wool or hair in dispute to be selected and tested by a commercial method approved by the...

  14. 75 FR 35044 - Notice of Approval of a Supplemental New Animal Drug Application; Penicillin G Procaine Suspension

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-21

    ...] Notice of Approval of a Supplemental New Animal Drug Application; Penicillin G Procaine Suspension AGENCY... Laboratories, Ltd. The supplemental NADA provides for a revised formulation of penicillin G procaine injectable... of NOROCILLIN (penicillin G procaine) Injectable Suspension by intramuscular injection in cattle...

  15. [Laboratory management fee in national health insurance; what is required from clinical laboratory physicians? --message from Chairpersons].

    PubMed

    Kimura, Satoshi; Koshiba, Masahiro

    2013-06-01

    The laboratory management fee (LMF) in national health insurance ("Kentai-Kensa-Kanri-Kasan" in Japanese) has had a major impact on Japanese clinical laboratories, especially in recent years. In 2012, the fee was raised to approximately 5,000 yen per admitted patient. In order to address this national support, clinical pathologists are required to increase their knowledge and skills. On the other hand, there are insufficient clinical pathologists in Japan. In order to solve this problem, the Japanese Society of Laboratory Medicine (JSLM) approved a new license for Qualified Clinical Laboratory Managing Physicians (CLMPs), in addition to Certified Clinical Laboratory Physicians (CCLPs). The requirements to become a CLMP are less strict than for CCLP. There are approximately 500 CLMPs and 600 CCLPs in this country. The aim of this symposium was to offer opportunities to increase attendees' clinical skills, especially CLMPs and young clinical pathologists. Four CCLPs were chosen as speakers from a university hospital, a major city hospital, a medium-sized acute care hospital, and a university hospital anatomical pathologist, together with a chief medical technologist from a university hospital. All the speakers presented their ideal role models of clinical pathologists matching LMF requirements. JSLM together with the Japanese Association of Clinical Laboratory Physicians (JACLaP) sponsored this symposium. It was a successful meeting with more than two hundred attendees.

  16. 7 CFR 1944.415 - Grant approval and other approving authorities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., DEPARTMENT OF AGRICULTURE (CONTINUED) PROGRAM REGULATIONS (CONTINUED) HOUSING Self-Help Technical Assistance... 7 Agriculture 13 2010-01-01 2009-01-01 true Grant approval and other approving authorities. 1944.415 Section 1944.415 Agriculture Regulations of the Department of Agriculture (Continued) RURAL...

  17. Laboratory Validation and Demonstrations of Non-Hexavalent Chromium Conversion Coatings for Steel Substrates (Briefing Charts)

    DTIC Science & Technology

    2011-02-01

    UNCLASSIFIED: Approved for public release; distribution unlimited. Laboratory Validation and Demonstrations of Non-Hexavalent Chromium Conversion...00-00-2011 4. TITLE AND SUBTITLE Laboratory Validation and Demonstrations of Non-Hexavalent Chromium Conversion Coatings for Steel Substrates 5a...Coatings for HHA • SurTec 650 - ChromitAL TCP - Trivalent Chrome Pretreatment Developed by NAVAIR for Aluminum. • Chemetall Oxsilan 9810/2 - Non-chrome

  18. INTER LABORATORY COMBAT HELMET BLUNT IMPACT TEST METHOD COMPARISON

    DTIC Science & Technology

    2018-03-26

    HELMET BLUNT IMPACT TEST METHOD COMPARISON by Tony J. Kayhart Charles A. Hewitt and Jonathan Cyganik March 2018 Final...Report March 2016 – August 2017 Approved for public release; distribution is unlimited U.S. Army Natick Soldier Research ...INTER-LABORATORY COMBAT HELMET BLUNT IMPACT TEST METHOD COMPARISON 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR

  19. 10 CFR 1016.8 - Approval for processing access permittees for security facility approval.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Approval for processing access permittees for security facility approval. 1016.8 Section 1016.8 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) SAFEGUARDING OF RESTRICTED DATA Physical Security § 1016.8 Approval for processing access permittees for security facility...

  20. 10 CFR 1016.8 - Approval for processing access permittees for security facility approval.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Approval for processing access permittees for security facility approval. 1016.8 Section 1016.8 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) SAFEGUARDING OF RESTRICTED DATA Physical Security § 1016.8 Approval for processing access permittees for security facility...

  1. Punishments: What Predicts Adult Approval.

    ERIC Educational Resources Information Center

    Buntain-Ricklefs, Joanne J.; And Others

    1994-01-01

    A survey of 449 parents found that 24% experienced uncommon punishments (such as burning) during their childhoods and 6% approved; 45% experienced and 17% approved of common punishments (shaking); and 94% experienced and 88% approved of very common punishments (spanking). Approval of each punishment was related to experience. Race, income, and…

  2. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hund, Gretchen

    For the past decade, a team at the Pacific Northwest National Laboratory (PNNL) has engaged industry to “go beyond compliance” in controlling and securing their supply chains to ensure their goods are not diverted to nuclear weapons programs. This work has focused on dual-use industries that manufacture products that can be used in both commercial applications and in the development of a nuclear weapon. The team encourages industry to self-regulate to reduce proliferation risks. As part of that work, PNNL interviewed numerous companies about their compliance practices in order to understand their business and to build awareness around best practicesmore » to ensure security of goods and information along their supply chains. As a result, PNNL has identified seven indicators that a company can adopt as part of their commitment to nonproliferation ideals.« less

  3. Walk the Talk: Progress in Building a Supply Chain Security Culture

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hund, Gretchen

    Pacific Northwest National Laboratory (PNNL) has engaged industry to “go beyond compliance” for over a decade in controlling and securing their supply chains to ensure their goods are not diverted to nuclear weapons programs. This work has focused on dual-use industries that manufacture products that can be used in both commercial applications and in the development of a nuclear weapon. The team encourages industry to self-regulate to reduce proliferation risks. As part of that work, PNNL interviewed numerous companies about their compliance practices to understand their business and to build awareness around best practices to ensure security of goods, technology,more » and information along their supply chains. From conducting this work, PNNL identified indicators that a company can adopt as part of its commitment to nonproliferation ideals with a focus on supply chain security.« less

  4. Redfield Energy Approval

    EPA Pesticide Factsheets

    This September 19, 2016 letter from EPA approves the petition from Poet Biorefining-Lake Crystal, regarding non-This October 27, 2016 letter from EPA approves the petition from Redfield Energy, LLC, regarding non-grandfathered ethanol produced

  5. Radiological Medical Device Innovation: Approvals via the Premarket Approval Pathway From 2000 to 2015.

    PubMed

    Ghobadi, Comeron W; Hayman, Emily L; Finkle, Joshua H; Walter, Jessica R; Xu, Shuai

    2017-01-01

    The aim of this study was to critically assess the clinical evidence leading to radiologic medical device approvals via the premarket approval pathway from 2000 to 2015. This study used the publically available FDA premarket database for radiologic device approvals over the past 15 years (September 1, 2000, to August 31, 2015). Approval characteristics were collected for each device, and statistical analysis was performed on the data for each pivotal trial. Additionally, methodological quality of the pivotal trial was determined using the Quality Assessment of Diagnostic Accuracy Studies tool. Twenty-three class III radiologic device approvals were identified, with breast imaging accounting for 16 (70%) and computer-aided detection software accounting for 9 (39%) approvals. The median premarket approval time was 475 days (range, 180-1,116). Twenty-one devices were approved on the basis of multireader, multicenter studies, one on the basis of a randomized controlled trial, and one on the basis of a preclinical technical equivalence trial. The median number of patients per pivotal trial was 201 (range, 25-3,946). Twenty-six of the 34 pivotal trials (76%) had at least one methodologic bias. Breast imaging devices had a greater number of patients per pivotal trial (P = .009) and more prospective studies. With regard to all modalities, increased time to device approval correlated with weaker trial quality (r = 0.600, P < .001). Radiologic devices are largely approved by multireader, multicenter studies, the recommended standard for assessing diagnostic technologies. Given that radiologic devices play a key role in modern medicine, further efforts should be made to increase transparency of clinical data leading to approval. Copyright © 2016 American College of Radiology. Published by Elsevier Inc. All rights reserved.

  6. Innovating by developing new uses of already-approved drugs: trends in the marketing approval of supplemental indications.

    PubMed

    DiMasi, Joseph A

    2013-06-01

    Much of the literature on trends and factors affecting biopharmaceutical innovation has focused overwhelmingly on the development and approval of never-before approved drugs and biologics. Little attention has been paid to new uses for already-approved compounds, which can be an important form of innovation. This paper aimed to determine and analyze recent trends in the number and type of new or modified US indication approvals for drugs and biologics. We also examine regulatory approval-phase times for new-use efficacy supplements and compare them to approval-phase times for original-use approvals over the same period. We developed a data set of efficacy supplements approved by the US Food and Drug Administration (FDA) from 1998 to 2011 that includes information on the type, approval-phase time (time from submission to the FDA of an application for marketing approval to approval of the application), and FDA therapeutic-significance rating for the approved application, which we obtained from an FDA Web site. This data set was merged with a Tufts Center for the Study of Drug Development (CSDD) data set of US new drug and biologics approvals. We developed descriptive statistics on trends in the number and type of new-use efficacy supplements, on US regulatory approval-phase times for the supplements, and on original new drug and biologics approvals over the study period and for the time from original- to new-use approval. The total number of new-use efficacy-supplement approvals did not exhibit a marked trend, but the number of new pediatric-indication approvals increased substantially. Approval-phase times for new-use supplements varied by therapeutic class and FDA therapeutic-significance rating. Mean approval-phase times were highest for central nervous system compounds (13.8 months) and lowest for antineoplastics (8.9 months). The mean time from original to supplement approval was substantially longer for new pediatric indications than for other new uses. Mean

  7. Performance evaluation for screening laboratories of the Asia-Pacific region.

    PubMed

    Hannon, W Harry

    2003-01-01

    The Centers for Disease Control and Prevention (CDC) has a long history of involvement in quality assurance (QA) activities for support of newborn screening laboratories. Since 1978, CDC's Newborn Screening Quality Assurance Program (NSQAP), has distributed dried-blood spot (DBS) materials for external QA and has maintained related projects to serve newborn screening laboratories. The first DBS materials were distributed for congenital hypothyroidism screening in 1978 and by 2001, NSQAP had expanded to over 30 disorders and performance monitoring for all filter paper production lots from approved commercial sources. In 2001, there were 250 active NSQAP participants, 167 laboratories from 45 countries and 83 laboratories in the United States. Of these laboratories, 31 are from the Asia Pacific Region representing nine countries primarily for two disorders. In 1999, US laboratories had more errors for Performance Evaluation (PE) specimens than other laboratories; but in 2000, US laboratories had fewer errors. International laboratories reported 0.3% false-negative PE clinical assessments for congenital hypothyroidism and 0.5% for phenylketonuria (0.5%) in 2000. Paperless PE data-reporting operation using an Internet website has recently been implemented.

  8. 78 FR 52556 - Accreditation and Approval of SGS North America, Inc., as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-23

    ... petroleum products, organic chemicals and vegetable oils for customs purposes for the next three years as of..., LA 70087, has been approved to gauge and accredited to test petroleum and petroleum products, organic chemicals and vegetable oils for customs purposes, in accordance with the provisions of 19 CFR 151.12 and 19...

  9. 38 CFR 21.292 - Course approvals.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Course approvals. 21.292... Course Approval and Facility Selection § 21.292 Course approvals. (a) Courses must be approved. Only those courses approved by the Department of Veterans Affairs shall be utilized to provide training and...

  10. 38 CFR 21.292 - Course approvals.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Course approvals. 21.292... Course Approval and Facility Selection § 21.292 Course approvals. (a) Courses must be approved. Only those courses approved by the Department of Veterans Affairs shall be utilized to provide training and...

  11. 38 CFR 21.292 - Course approvals.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Course approvals. 21.292... Course Approval and Facility Selection § 21.292 Course approvals. (a) Courses must be approved. Only those courses approved by the Department of Veterans Affairs shall be utilized to provide training and...

  12. 38 CFR 21.292 - Course approvals.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Course approvals. 21.292... Course Approval and Facility Selection § 21.292 Course approvals. (a) Courses must be approved. Only those courses approved by the Department of Veterans Affairs shall be utilized to provide training and...

  13. 38 CFR 21.292 - Course approvals.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Course approvals. 21.292... Course Approval and Facility Selection § 21.292 Course approvals. (a) Courses must be approved. Only those courses approved by the Department of Veterans Affairs shall be utilized to provide training and...

  14. Predictive Engineering Tools for Injection-Molded Long-Carbon-Fiber Thermoplastic Composites - FY 2014 First Quarterly Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nguyen, Ba Nghiep; Sanborn, Scott E.; Simmons, Kevin L.

    2014-02-19

    The CRADA between PNNL, Autodesk, Toyota and Magna has been effective since October 28th, 2013. The whole team including CRADA and subcontract partners kicked off the project technically on November 1st, 2013. This report describes work performed during the first quarter of FY 2014. The following technical progresses have been made toward project milestones: 1) The project kickoff meeting was organized at PlastiComp, Inc. in Winona on November 13th, 2013 involving all the project partners. During this meeting the research plan and Gantt chart were discussed and refined. The coordination of the research activities among the partners was also discussedmore » to ensure that the deliverables and timeline will be met. 2) Autodesk delivered a research version of ASMI to PNNL for process modeling using this tool under the project. PNNL installed this research version on a PNNL computer and tested it. Currently, PNNL is using ASMI to prepare the models for PlastiComp plaques. 3) PlastiComp has compounded long carbon-fiber reinforced polypropylene and polyamide 6,6 compounds for rheological and thermal characterization tests by the Autodesk laboratories in Melbourne, Australia. 4) Initial mold flow analysis was carried out by PlastiComp to confirm that the 3D complex part selected by Toyota as a representative automotive part is moldable. 5) Toyota, Magna, PlastiComp and PNNL finalized the planning for molding the Toyota 3D complex part. 6) Purdue University worked with PNNL to update and specify the test matrix for characterization of fiber length/orientation. 7) Purdue University developed tools to automate the data collection and analysis of fiber length and orientation measurements. 8) Purdue University designed and specified equipment to replace the need for equipment using the technology established by the University of Leeds at General Motors.« less

  15. Laboratory Testing of Electro-Osmotic Pulse Technology to Reduce and Maintain Low Moisture Content in Concrete

    DTIC Science & Technology

    2009-02-01

    technology minimizes harmful effects to concrete and rebar and prevents over drying, pore blocking and electrode polarization. Principles of EOP...LABORATORY TESTING OF ELECTRO-OSMOTIC PULSE TECHNOLOGY TO REDUCE AND MAINTAIN LOW MOISTURE CONTENT IN CONCRETE Orange S. Marshall, Vincent F...Laboratory 2009 Army Corrosion Summit Clearwater Beach, FL 6 January 2009 Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting

  16. 78 FR 65030 - Agency Requests for Renewal of a Previously Approved Information Collection(s): Approval of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-30

    ... Previously Approved Information Collection(s): Approval of Underwriters of Marine Hull Insurance AGENCY...: Approval of Underwriters of Marine Hull Insurance. Form Numbers: None. Type of Review: Renewal of an... approval of marine hull underwriters to insure Maritime Administration program vessels. Foreign and...

  17. Simulation of outdoor pond cultures using indoor LED-lighted and temperature-controlled raceway ponds and Phenometrics photobioreactors

    DOE PAGES

    Huesemann, Michael; Dale, T.; Chavis, A.; ...

    2016-12-02

    Two innovative culturing systems, the LED-lighted and temperature-controlled 800 liter indoor raceways at Pacific Northwest National Laboratory (PNNL) and the Phenometrics environmental Photobioreactors™ (ePBRs) were evaluated in terms of their ability to accurately simulate the microalgae growth performance of outdoor cultures subjected to fluctuating sunlight and water temperature conditions. When repeating a 60-day outdoor pond culture experiment (batch and semi-continuous at two dilution rates) conducted in Arizona with the freshwater strain Chlorella sorokiniana DOE 1412 in these two indoor simulators, it was found that ash-free dry weight based biomass growth and productivity in the PNNL climate-simulation ponds was comparatively slightlymore » higher (8–13%) but significantly lower (44%) in the ePBRs. The difference in biomass productivities between the indoor and outdoor ponds was not statistically significant. When the marine Picochlorum soloecismus was cultured in five replicate ePBRs at Los Alamos National Laboratory (LANL) and in duplicate indoor climate-simulation ponds at PNNL, using the same inoculum, medium, culture depth, and light and temperature scripts, the optical density based biomass productivity and the rate of increase in cell counts in the ePBRs was about 35% and 66%, respectively, lower compared than in the indoor ponds. Potential reasons for the divergence in growth performance in these pond simulators, relative to outdoor raceways, are discussed. In conclusion, the PNNL climate-simulation ponds provide reasonably reliable biomass productivity estimates for microalgae strains cultured in outdoor raceways under different climatic conditions.« less

  18. Joint Institute for Nanoscience Annual Report 2003

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Baer, Donald R.; Campbell, Charles

    2004-02-01

    The Joint Institute for Nanoscience (JIN) is a cooperative venture of the University of Washington and Pacific Northwest National Laboratory to encourage and enhance high-impact and high-quality nanoscience and nanotechnology of all types. This first annual report for the JIN summarizes activities beginning in 2001 and ending at the close of fiscal year 2003 and therefore represents somewhat less than two years of activities. Major portions of the JIN resources are dedicated to funding graduate students and postdoctoral research associates to perform research in collaborations jointly directed by Pacific Northwest National Laboratory (PNNL) staff scientists and University of Washington (UW)more » professors. These fellowships were awarded on the basis of applications that included research proposals. JIN co-sponsors an annual Nanoscale Science and Technology Workshop held in Seattle. In addition to involving PNNL staff in various UW nanoscience courses and seminars, a National Science Foundation grant Development of UW-PNL Collaborative Curriculums in Nano-Science and Technology has allowed the development of three intensive short courses that are taught by UW faculty, PNNL staff, and faculty from other institutions, including Washington State University, the University of Idaho, Stanford University, and the University of Alaska. The initial JIN agreement recognized that expansion of cooperation beyond UW and PNNL would be highly valuable. Starting in early 2003, efforts were initiated to form a regional communication link called the Northwest Nanoscience and Nanotechnology Network (N₄). In concept, N₄ is a tool to encourage communication and help identify regional resources and nanoscience and technology activities.« less

  19. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huesemann, Michael; Dale, T.; Chavis, A.

    Two innovative culturing systems, the LED-lighted and temperature-controlled 800 liter indoor raceways at Pacific Northwest National Laboratory (PNNL) and the Phenometrics environmental Photobioreactors™ (ePBRs) were evaluated in terms of their ability to accurately simulate the microalgae growth performance of outdoor cultures subjected to fluctuating sunlight and water temperature conditions. When repeating a 60-day outdoor pond culture experiment (batch and semi-continuous at two dilution rates) conducted in Arizona with the freshwater strain Chlorella sorokiniana DOE 1412 in these two indoor simulators, it was found that ash-free dry weight based biomass growth and productivity in the PNNL climate-simulation ponds was comparatively slightlymore » higher (8–13%) but significantly lower (44%) in the ePBRs. The difference in biomass productivities between the indoor and outdoor ponds was not statistically significant. When the marine Picochlorum soloecismus was cultured in five replicate ePBRs at Los Alamos National Laboratory (LANL) and in duplicate indoor climate-simulation ponds at PNNL, using the same inoculum, medium, culture depth, and light and temperature scripts, the optical density based biomass productivity and the rate of increase in cell counts in the ePBRs was about 35% and 66%, respectively, lower compared than in the indoor ponds. Potential reasons for the divergence in growth performance in these pond simulators, relative to outdoor raceways, are discussed. In conclusion, the PNNL climate-simulation ponds provide reasonably reliable biomass productivity estimates for microalgae strains cultured in outdoor raceways under different climatic conditions.« less

  20. X-ray scan detection for cargo integrity

    NASA Astrophysics Data System (ADS)

    Valencia, Juan; Miller, Steve

    2011-04-01

    The increase of terrorism and its global impact has made the determination of the contents of cargo containers a necessity. Existing technology allows non-intrusive inspections to determine the contents of a container rapidly and accurately. However, some cargo shipments are exempt from such inspections. Hence, there is a need for a technology that enables rapid and accurate means of detecting whether such containers were non-intrusively inspected. Non-intrusive inspections are most commonly performed utilizing high powered X-ray equipment. The challenge is creating a device that can detect short duration X-ray scans while maintaining a portable, battery powered, low cost, and easy to use platform. The Pacific Northwest National Laboratory (PNNL) has developed a methodology and prototype device focused on this challenge. The prototype, developed by PNNL, is a battery powered electronic device that continuously measures its X-ray and Gamma exposure, calculates the dose equivalent rate, and makes a determination of whether the device has been exposed to the amount of radiation experienced during an X-ray inspection. Once an inspection is detected, the device will record a timestamp of the event and relay the information to authorized personnel via a visual alert, USB connection, and/or wireless communication. The results of this research demonstrate that PNNL's prototype device can be effective at determining whether a container was scanned by X-ray equipment typically used for cargo container inspections. This paper focuses on laboratory measurements and test results acquired with the PNNL prototype device using several X-ray radiation levels.

  1. NATIONAL ENVIRONMENTAL LABORATORY ACCREDITATION CONFERENCE; CONSTITUTION, BYLAWS AND STANDARDS: APPROVED MAY 25, 2001

    EPA Science Inventory

    The principles and operating procedures for the National Environmental Laboratory Accreditation Conference (NELAC) are contained in the NELAC Constitution and Bylaws. The major portion of this document (standards) contains detailed requirements for accrediting environmental labo...

  2. Drugs Approved for Brain Tumors

    MedlinePlus

    ... Ask about Your Treatment Research Drugs Approved for Brain Tumors This page lists cancer drugs approved by ... that are not listed here. Drugs Approved for Brain Tumors Afinitor (Everolimus) Afinitor Disperz (Everolimus) Avastin (Bevacizumab) ...

  3. 38 CFR 21.7720 - Course approval.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Course approval. 21.7720... of Courses § 21.7720 Course approval. (a) Courses must be approved. (1) A course of education offered...)(iii), and (c)(2)(iv) apply. (3) A course approved under 38 U.S.C. chapter 36 is approved for purposes...

  4. 38 CFR 21.7720 - Course approval.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Course approval. 21.7720... of Courses § 21.7720 Course approval. (a) Courses must be approved. (1) A course of education offered...)(iii), and (c)(2)(iv) apply. (3) A course approved under 38 U.S.C. chapter 36 is approved for purposes...

  5. 38 CFR 21.7720 - Course approval.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Course approval. 21.7720... of Courses § 21.7720 Course approval. (a) Courses must be approved. (1) A course of education offered...)(iii), and (c)(2)(iv) apply. (3) A course approved under 38 U.S.C. chapter 36 is approved for purposes...

  6. 38 CFR 21.7720 - Course approval.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Course approval. 21.7720... of Courses § 21.7720 Course approval. (a) Courses must be approved. (1) A course of education offered...)(iii), and (c)(2)(iv) apply. (3) A course approved under 38 U.S.C. chapter 36 is approved for purposes...

  7. 18 CFR 806.31 - Term of approvals.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... approval issued under this part shall be no longer than 15 years or the anticipated life of the project... AND APPROVAL OF PROJECTS Terms and Conditions of Approval § 806.31 Term of approvals. (a) Approvals... approval of a project shall expire three years from the date of such approval if the withdrawal, diversion...

  8. A Living Laboratory for Building-Grid Integration

    ScienceCinema

    Shankle, Steve; Goyal, Siddharth

    2018-01-16

    At PNNL we’re developing a test bed for control of how buildings interact with the grid—an important step toward helping buildings achieve their potential for reducing energy use and improving the management of the nation’s power systems. The test bed works by allowing researchers to conduct experiments on PNNL’s specially-equipped Systems Engineering Building. This unique resource will help the Department of Energy achieve its mission of reducing buildings energy use by 50 percent by 2030.

  9. 42 CFR 493.2001 - Establishment and function of the Clinical Laboratory Improvement Advisory Committee.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... laboratory testing or methodology, and others as approved by HHS. (c) HHS will designate specialized...: (1) Criteria for categorizing nonwaived testing; (2) Determination of waived tests; (3) Personnel standards; (4) Facility administration and quality systems standards. (5) Proficiency testing standards; (6...

  10. 42 CFR 493.2001 - Establishment and function of the Clinical Laboratory Improvement Advisory Committee.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... laboratory testing or methodology, and others as approved by HHS. (c) HHS will designate specialized...: (1) Criteria for categorizing nonwaived testing; (2) Determination of waived tests; (3) Personnel standards; (4) Facility administration and quality systems standards. (5) Proficiency testing standards; (6...

  11. 42 CFR 493.2001 - Establishment and function of the Clinical Laboratory Improvement Advisory Committee.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... laboratory testing or methodology, and others as approved by HHS. (c) HHS will designate specialized...: (1) Criteria for categorizing nonwaived testing; (2) Determination of waived tests; (3) Personnel standards; (4) Facility administration and quality systems standards. (5) Proficiency testing standards; (6...

  12. Non-Cooperative Facial Recognition Video Dataset Collection Plan

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kimura, Marcia L.; Erikson, Rebecca L.; Lombardo, Nicholas J.

    The Pacific Northwest National Laboratory (PNNL) will produce a non-cooperative (i.e. not posing for the camera) facial recognition video data set for research purposes to evaluate and enhance facial recognition systems technology. The aggregate data set consists of 1) videos capturing PNNL role players and public volunteers in three key operational settings, 2) photographs of the role players for enrolling in an evaluation database, and 3) ground truth data that documents when the role player is within various camera fields of view. PNNL will deliver the aggregate data set to DHS who may then choose to make it available tomore » other government agencies interested in evaluating and enhancing facial recognition systems. The three operational settings that will be the focus of the video collection effort include: 1) unidirectional crowd flow 2) bi-directional crowd flow, and 3) linear and/or serpentine queues.« less

  13. A laboratory silicone for preclinical training in ear prosthesis.

    PubMed

    Anand, Vijay; Haribabu; Vimala; Gnanasamband, Vimala

    2013-07-01

    This article describes an industrial elastic silicone as a material for the laboratory fabrication of ear prosthesis. It has been tested for toxicity in lab animals by the SGS India Pvt. Ltd and approved as a material to pass the parameter of abnormal toxicity. This material therefore can be safely recommended for laboratory exercise to fabricate facial prosthesis. The high cost of the maxillo facial silicone materials prohibits their use for facial prosthesis in pre-clinical training of post-graduate students in maxillofacial prosthodontics. For this reason, pre-clinical laboratory exercise in facial prosthesis is inadequate. A few institutions use polymethyl methacrylate resins which are rigid and do not have elastic characteristics of silicone, which is used for facial defects. This cost-effective industrial silicone material which mimics the elastic and color characteristics of the conventional silicones can be recommended for preclinical exercises.

  14. 49 CFR 451.1 - Application for approval.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of Existing Containers § 451.1 Application for approval. (a) Any owner of an existing container may apply for approval to... to any Approval Authority. (b) Each application must include the following for each container: (1...

  15. 49 CFR 451.1 - Application for approval.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of Existing Containers § 451.1 Application for approval. (a) Any owner of an existing container may apply for approval to... to any Approval Authority. (b) Each application must include the following for each container: (1...

  16. 49 CFR 451.1 - Application for approval.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of Existing Containers § 451.1 Application for approval. (a) Any owner of an existing container may apply for approval to... to any Approval Authority. (b) Each application must include the following for each container: (1...

  17. 30 CFR 7.49 - Approval marking.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... MINING PRODUCTS TESTING BY APPLICANT OR THIRD PARTY Battery Assemblies § 7.49 Approval marking. Each approved battery assembly shall be identified by a legible and permanent approval plate inscribed with the assigned MSHA approval number and securely attached to the battery box. ...

  18. 30 CFR 7.49 - Approval marking.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... MINING PRODUCTS TESTING BY APPLICANT OR THIRD PARTY Battery Assemblies § 7.49 Approval marking. Each approved battery assembly shall be identified by a legible and permanent approval plate inscribed with the assigned MSHA approval number and securely attached to the battery box. ...

  19. 30 CFR 7.49 - Approval marking.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... MINING PRODUCTS TESTING BY APPLICANT OR THIRD PARTY Battery Assemblies § 7.49 Approval marking. Each approved battery assembly shall be identified by a legible and permanent approval plate inscribed with the assigned MSHA approval number and securely attached to the battery box. ...

  20. Homogeneous Hydrogenation of CO₂ to Methyl Formate Utilizing Switchable Ionic Liquids

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yadav, Mahendra; Linehan, John C.; Karkamkar, Abhijeet J.

    2014-09-15

    Capture of CO₂ and subsequent hydrogenation allows for base/alcohol-catalyzed conversion of CO₂ to methylformate in one pot. The conversion of CO₂ proceeds via alkylcarbonates, to formate salts and then formate esters, which can be catalyzed by base and alcohol with the only byproduct being water. The system operates at mild conditions (300 psi H₂, 140 °C). Reactivity is strongly influenced by temperature and choice of solvent. In the presence of excess of base (DBU) formate is predominant product while in excess of methanol methyl formate is major product. 110 °C yields formate salts, 140 °C promotes methylformate. The authors acknowledgemore » internal Laboratory Directed Re-search and Development (LDRD) funding from Pacific Northwest National Laboratory (PNNL). PNNL is operated by Battelle for the U.S. Department of Energy.« less

  1. Final Report - IHLW PCT, Spinel T1%, Electrical Conductivity, and Viscosity Model Development, VSL-07R1240-4

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kruger, Albert A.; Piepel, Gregory F.; Landmesser, S. M.

    2013-11-13

    This report is the last in a series of currently scheduled reports that presents the results from the High Level Waste (HLW) glass formulation development and testing work performed at the Vitreous State Laboratory (VSL) of the Catholic University of America (CUA) and the development of IHLW property-composition models performed jointly by Pacific Northwest National Laboratory (PNNL) and VSL for the River Protection Project-Waste Treatment and Immobilization Plant (RPP-WTP). Specifically, this report presents results of glass testing at VSL and model development at PNNL for Product Consistency Test (PCT), one-percent crystal fraction temperature (T1%), electrical conductivity (EC), and viscosity ofmore » HLW glasses. The models presented in this report may be augmented and additional validation work performed during any future immobilized HLW (IHLW) model development work. Completion of the test objectives is addressed.« less

  2. Point-of-care diagnostics: extending the laboratory network to reach the last mile.

    PubMed

    Drain, Paul K; Rousseau, Christine

    2017-03-01

    More point-of-care (POC) diagnostic tests are becoming available for HIV diagnosis and treatment in resource-limited settings. These novel technologies have the potential to foster decentralized HIV care and treatment for the benefit of clinical laboratories, HIV clinics, and HIV-infected patients. There continue to be many business, technological, and operational challenges that limit product development and regulatory approval, which limits products available for the required operational and cost-effectiveness studies and delays policy adoption and implementation. Although the rapid HIV diagnostic test has been widely successful, the pathways for POC CD4 cell count and HIV viral load assay analyzers have been more challenging. We describe significant hurdles for product development, approval, and implementation, which include the business case, technical development, clinical impact, and integrating laboratory and clinical networks. The objective of this review is to highlight the obstacles for developing and implementing appropriate strategies for POC HIV testing assays to improve the clinical services for HIV-infected patients in resource-limited settings.

  3. Laboratory Evaluation of Nitrile Fuel Tank Materials (Phase 2)

    DTIC Science & Technology

    2013-09-01

    NOTICES Disclaimers The findings in this report are not to be construed as an official Department of the Army position unless so designated...by other authorized documents. Citation of manufacturer’s or trade names does not constitute an official endorsement or approval of the use...thereof. Destroy this report when it is no longer needed. Do not return it to the originator. Army Research Laboratory Aberdeen Proving Ground, MD

  4. Predictive Engineering Tools for Injection-Molded Long-Carbon-Fiber Thermoplastic Composites - FY13 Third Quarterly Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nguyen, Ba Nghiep; Simmons, Kevin L.

    2013-08-06

    This quarterly report summarizes the status for the project planning to obtain all the approvals required for a Cooperative Research and Development Agreement (CRADA) with Autodesk, Inc., Toyota Motor Engineering and Manufacturing North America (Toyota), and Magna Exterior and Interiors Corporation (Magna). The CRADA documents have been processed by PNNL Legal Services that is also coordinating the revision effort with the industrial parties to address DOE’s comments.

  5. Molecular Dynamics and Theoretical Chemistry

    DTIC Science & Technology

    2013-03-08

    and structural stability compared to H-Si(111) • Air- and electrochemical-stability enables advanced sensors, fuel and solar cells , etc. • Probes...Diagnostics ARO – plasmonics AFOSR - Endo fuels, combustion, solar PNNL – Institute for Integrated Catalysis Navy, DTRA – Clusters AFRL, NASA, DoD...Propellants • Real-time probing of reactions • Hybrid Chemical Lasers • Sensors for Trace Detection Distribution A: Approved for public release

  6. 42 CFR 84.50 - Types of respirators to be approved; scope of approval.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES... provide respiratory protection for fixed periods of time against the hazards specified in such approval. ...

  7. 42 CFR 84.50 - Types of respirators to be approved; scope of approval.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES... provide respiratory protection for fixed periods of time against the hazards specified in such approval. ...

  8. 42 CFR 84.50 - Types of respirators to be approved; scope of approval.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES... provide respiratory protection for fixed periods of time against the hazards specified in such approval. ...

  9. 42 CFR 84.50 - Types of respirators to be approved; scope of approval.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES... provide respiratory protection for fixed periods of time against the hazards specified in such approval. ...

  10. 42 CFR 84.50 - Types of respirators to be approved; scope of approval.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES... provide respiratory protection for fixed periods of time against the hazards specified in such approval. ...

  11. 28 CFR 2.41 - Travel approval.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Travel approval. 2.41 Section 2.41..., YOUTH OFFENDERS, AND JUVENILE DELINQUENTS United States Code Prisoners and Parolees § 2.41 Travel approval. (a) The probation officer may approve travel outside the district without approval of the...

  12. 40 CFR 52.1522 - Approval status.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) New Hampshire § 52.1522 Approval status. (a) With the exceptions set forth in this subpart, the Administrator approves New Hampshire's plan as... Federal approval of State issued new source review permits pursuant to section 173 of the Clean Air Act...

  13. 40 CFR 52.1522 - Approval status.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) New Hampshire § 52.1522 Approval status. (a) With the exceptions set forth in this subpart, the Administrator approves New Hampshire's plan as... Federal approval of State issued new source review permits pursuant to section 173 of the Clean Air Act...

  14. 40 CFR 52.1522 - Approval status.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) New Hampshire § 52.1522 Approval status. (a) With the exceptions set forth in this subpart, the Administrator approves New Hampshire's plan as... Federal approval of State issued new source review permits pursuant to section 173 of the Clean Air Act...

  15. 40 CFR 52.1522 - Approval status.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) New Hampshire § 52.1522 Approval status. (a) With the exceptions set forth in this subpart, the Administrator approves New Hampshire's plan as... Federal approval of State issued new source review permits pursuant to section 173 of the Clean Air Act...

  16. 78 FR 32558 - Expedited Approval of Alternative Test Procedures for the Analysis of Contaminants Under the Safe...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-31

    ...This action announces the U.S. Environmental Protection Agency's (EPA's) approval of alternative testing methods for use in measuring the levels of contaminants in drinking water and determining compliance with national primary drinking water regulations. The Safe Drinking Water Act (SDWA) authorizes EPA to approve the use of alternative testing methods through publication in the Federal Register. EPA is using this streamlined authority to make 84 additional methods available for analyzing drinking water samples. This expedited approach provides public water systems, laboratories, and primacy agencies with more timely access to new measurement techniques and greater flexibility in the selection of analytical methods, thereby reducing monitoring costs while maintaining public health protection.

  17. 46 CFR 11.302 - Course approval.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 1 2013-10-01 2013-10-01 false Course approval. 11.302 Section 11.302 Shipping COAST... ENDORSEMENTS Training Schools with Approved Courses § 11.302 Course approval. (a) The Coast Guard approves courses satisfying regulatory requirements and those that substitute for a Coast Guard examination or a...

  18. 46 CFR 11.302 - Course approval.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 1 2011-10-01 2011-10-01 false Course approval. 11.302 Section 11.302 Shipping COAST... ENDORSEMENTS Training Schools with Approved Courses § 11.302 Course approval. (a) The Coast Guard approves courses satisfying regulatory requirements and those that substitute for a Coast Guard examination or a...

  19. 46 CFR 11.302 - Course approval.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Course approval. 11.302 Section 11.302 Shipping COAST... ENDORSEMENTS Training Schools with Approved Courses § 11.302 Course approval. (a) The Coast Guard approves courses satisfying regulatory requirements and those that substitute for a Coast Guard examination or a...

  20. 46 CFR 11.302 - Course approval.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 1 2012-10-01 2012-10-01 false Course approval. 11.302 Section 11.302 Shipping COAST... ENDORSEMENTS Training Schools with Approved Courses § 11.302 Course approval. (a) The Coast Guard approves courses satisfying regulatory requirements and those that substitute for a Coast Guard examination or a...

  1. 38 CFR 21.7220 - Course approval.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Course approval. 21.7220... Bill-Active Duty) Approval of Courses § 21.7220 Course approval. (a) Courses must be approved. (1) A course of education, including the class schedules of a resident course not leading to a standard college...

  2. 38 CFR 21.7220 - Course approval.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Course approval. 21.7220... Bill-Active Duty) Approval of Courses § 21.7220 Course approval. (a) Courses must be approved. (1) A course of education, including the class schedules of a resident course not leading to a standard college...

  3. 38 CFR 21.7220 - Course approval.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Course approval. 21.7220... Bill-Active Duty) Approval of Courses § 21.7220 Course approval. (a) Courses must be approved. (1) A course of education, including the class schedules of a resident course not leading to a standard college...

  4. 38 CFR 21.7220 - Course approval.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Course approval. 21.7220... Bill-Active Duty) Approval of Courses § 21.7220 Course approval. (a) Courses must be approved. (1) A course of education, including the class schedules of a resident course not leading to a standard college...

  5. 9 CFR 147.52 - Approved tests.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Approved tests. 147.52 Section 147.52... Approved Tests § 147.52 Approved tests. (a) The procedures for the bacteriological examination of poultry and poultry environments described in this part are approved tests for use in the NPIP. In addition...

  6. 9 CFR 147.52 - Approved tests.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Approved tests. 147.52 Section 147.52... Approved Tests § 147.52 Approved tests. (a) The procedures for the bacteriological examination of poultry and poultry environments described in this part are approved tests for use in the NPIP. In addition...

  7. Atezolizumab: First Global Approval.

    PubMed

    Markham, Anthony

    2016-08-01

    Atezolizumab (Tecentriq™)-a monoclonal antibody targeting programmed death ligand 1 (PD-L1 or CD274 antigen)-is being developed by Genentech as treatment for a variety of haematological malignancies and solid tumours. It been approved in the US as a second-line therapy for urothelial carcinoma and is awaiting approval as a second-line therapy for non-small cell lung cancer. This article summarizes the milestones in the development of atezolizumab leading to this first approval for urothelial carcinoma.

  8. FDA approval of cardiac implantable electronic devices via original and supplement premarket approval pathways, 1979-2012.

    PubMed

    Rome, Benjamin N; Kramer, Daniel B; Kesselheim, Aaron S

    The US Food and Drug Administration (FDA) evaluates high-risk medical devices such as cardiac implantable electronic devices (CIEDs), including pacemakers, implantable cardioverter-defibrillators, and cardiac resynchronization therapy devices, via the premarket approval (PMA) process, during which manufacturers submit clinical data demonstrating safety and effectiveness. Subsequent changes to approved high-risk devices are implemented via "supplements," which may not require additional clinical testing. To characterize the prevalence and characteristics of changes to CIEDs made through the PMA supplement process. Using the FDA's PMA database, we reviewed all CIEDs approved as original PMAs or supplements from 1979 through 2012. For each supplement, we collected the date approved, type of supplement (panel-track, 180-day, real-time, special, and 30-day notice), and the nature of the changes. We calculated the number of supplements approved per PMA and analyzed trends relating to different supplement regulatory categories over time. For supplements approved via the 180-day regulatory pathway, which often involve significant design changes, from 2010-2012, we identified how often additional clinical data were collected. From 1979-2012, the FDA approved 77 original and 5829 supplement PMA applications for CIEDs, with a median of 50 supplements per original PMA (interquartile range [IQR], 23-87). Excluding manufacturing changes that do not alter device design, the number of supplements approved each year was stable around a mean (SD) of 2.6 (0.9) supplements per PMA per year. Premarket approvals remained active via successive supplements over a median period of 15 years (IQR, 8-20), and 79% of the 77 original PMAs approved during our study period were the subject of at least 1 supplement in 2012. Thirty-seven percent of approved supplements involved a change to the device's design. Among 180-day supplements approved from 2010-2012, 23% (15/64) included new clinical data

  9. FDA Approves Immunotherapy for a Cancer that Affects Infants and Children | Poster

    Cancer.gov

    By Frank Blanchard, Staff Writer The U.S. Food and Drug Administration (FDA) recently approved dinutuximab (ch14.18) as an immunotherapy for neuroblastoma, a rare type of childhood cancer that offers poor prognosis for about half of the children who are affected. The National Cancer Institute’s (NCI) Biopharmaceutical Development Program (BDP) at the Frederick National Laboratory for Cancer Research produced ch14.18 for the NCI-sponsored clinical trials that proved the drug’s effectiveness against the disease.

  10. 14 CFR 21.325 - Export airworthiness approvals.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Export airworthiness approvals. 21.325... AIRCRAFT CERTIFICATION PROCEDURES FOR PRODUCTS AND PARTS Export Airworthiness Approvals § 21.325 Export airworthiness approvals. (a) Kinds of approvals. (1) Export airworthiness approval of Class I products is issued...

  11. 49 CFR 451.1 - Application for approval.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of Existing Containers § 451.1 Application for approval. (a) Any owner of an existing container may apply for approval to.... (b) Each application must include the following for each container: (1) Date and place of manufacture...

  12. 49 CFR 451.1 - Application for approval.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of Existing Containers § 451.1 Application for approval. (a) Any owner of an existing container may apply for approval to.... (b) Each application must include the following for each container: (1) Date and place of manufacture...

  13. EC4 European Syllabus for Post-Graduate Training in Clinical Chemistry and Laboratory Medicine: version 3 - 2005.

    PubMed

    Zerah, Simone; McMurray, Janet; Bousquet, Bernard; Baum, Hannsjorg; Beastall, Graham H; Blaton, Vic; Cals, Marie-Josèphe; Duchassaing, Danielle; Gaudeau-Toussaint, Marie-Françoise; Harmoinen, Aimo; Hoffmann, Hans; Jansen, Rob T; Kenny, Desmond; Kohse, Klaus P; Köller, Ursula; Gobert, Jean-Gérard; Linget, Christine; Lund, Erik; Nubile, Giuseppe; Opp, Matthias; Pazzagli, Mario; Pinon, Georges; Queralto, José M; Reguengo, Henrique; Rizos, Demetrios; Szekeres, Thomas; Vidaud, Michel; Wallinder, Hans

    2006-01-01

    The EC4 Syllabus for Postgraduate Training is the basis for the European Register of Specialists in Clinical Chemistry and Laboratory Medicine. The syllabus: Indicates the level of requirements in postgraduate training to harmonise the postgraduate education in the European Union (EU); Indicates the level of content of national training programmes to obtain adequate knowledge and experience; Is approved by all EU societies for clinical chemistry and laboratory medicine. The syllabus is not primarily meant to be a training guide, but on the basis of the overview given (common minimal programme), national societies should formulate programmes that indicate where knowledge and experience is needed. The main points of this programme are: Indicates the level of requirements in postgraduate training to harmonise the postgraduate education in the European Union (EU); Indicates the level of content of national training programmes to obtain adequate knowledge and experience; Is approved by all EU societies for clinical chemistry and laboratory medicine. Knowledge in biochemistry, haematology, immunology, etc.; Pre-analytical conditions; Evaluation of results; Interpretations (post-analytical phase); Laboratory management; and Quality insurance management. The aim of this version of the syllabus is to be in accordance with the Directive of Professional Qualifications published on 30 September 2005. To prepare the common platforms planned in this directive, the disciplines are divided into four categories: Indicates the level of requirements in postgraduate training to harmonise the postgraduate education in the European Union (EU); Indicates the level of content of national training programmes to obtain adequate knowledge and experience; Is approved by all EU societies for clinical chemistry and laboratory medicine. Knowledge in biochemistry, haematology, immunology, etc.; Pre-analytical conditions; Evaluation of results; Interpretations (post-analytical phase); Laboratory

  14. 40 CFR 52.1972 - Approval status.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oregon § 52.1972 Approval status. With the exceptions set forth in this subpart, the Administrator approves Oregon's plan for the attainment and...

  15. 40 CFR 52.1972 - Approval status.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oregon § 52.1972 Approval status. With the exceptions set forth in this subpart, the Administrator approves Oregon's plan for the attainment and...

  16. 40 CFR 52.1972 - Approval status.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oregon § 52.1972 Approval status. With the exceptions set forth in this subpart, the Administrator approves Oregon's plan for the attainment and...

  17. 40 CFR 52.1972 - Approval status.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oregon § 52.1972 Approval status. With the exceptions set forth in this subpart, the Administrator approves Oregon's plan for the attainment and...

  18. 40 CFR 52.1223 - Approval status.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Minnesota § 52.1223 Approval status. With the exceptions set forth in this subpart, the Administrator approves Minnesota's plans for the attainment and...

  19. 40 CFR 52.1223 - Approval status.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Minnesota § 52.1223 Approval status. With the exceptions set forth in this subpart, the Administrator approves Minnesota's plans for the attainment and...

  20. 40 CFR 52.1223 - Approval status.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Minnesota § 52.1223 Approval status. With the exceptions set forth in this subpart, the Administrator approves Minnesota's plans for the attainment and...

  1. 40 CFR 52.1223 - Approval status.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Minnesota § 52.1223 Approval status. With the exceptions set forth in this subpart, the Administrator approves Minnesota's plans for the attainment and...

  2. 40 CFR 52.1223 - Approval status.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Minnesota § 52.1223 Approval status. With the exceptions set forth in this subpart, the Administrator approves Minnesota's plans for the attainment and...

  3. 40 CFR 52.2722 - Approval status.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Puerto Rico § 52.2722 Approval status. With the exceptions set forth in this subpart, the Administrator approves Puerto Rico's plans for the...

  4. 40 CFR 52.2722 - Approval status.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Puerto Rico § 52.2722 Approval status. With the exceptions set forth in this subpart, the Administrator approves Puerto Rico's plans for the...

  5. 40 CFR 52.2722 - Approval status.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Puerto Rico § 52.2722 Approval status. With the exceptions set forth in this subpart, the Administrator approves Puerto Rico's plans for the...

  6. Version 2.0 Visual Sample Plan (VSP): UXO Module Code Description and Verification

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gilbert, Richard O.; Wilson, John E.; O'Brien, Robert F.

    2003-05-06

    The Pacific Northwest National Laboratory (PNNL) is developing statistical methods for determining the amount of geophysical surveys conducted along transects (swaths) that are needed to achieve specified levels of confidence of finding target areas (TAs) of anomalous readings and possibly unexploded ordnance (UXO) at closed, transferring and transferred (CTT) Department of Defense (DoD) ranges and other sites. The statistical methods developed by PNNL have been coded into the UXO module of the Visual Sample Plan (VSP) software code that is being developed by PNNL with support from the DoD, the U.S. Department of Energy (DOE, and the U.S. Environmental Protectionmore » Agency (EPA). (The VSP software and VSP Users Guide (Hassig et al, 2002) may be downloaded from http://dqo.pnl.gov/vsp.) This report describes and documents the statistical methods developed and the calculations and verification testing that have been conducted to verify that VSPs implementation of these methods is correct and accurate.« less

  7. Biaxial Creep Specimen Fabrication

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    JL Bump; RF Luther

    This report documents the results of the weld development and abbreviated weld qualification efforts performed by Pacific Northwest National Laboratory (PNNL) for refractory metal and superalloy biaxial creep specimens. Biaxial creep specimens were to be assembled, electron beam welded, laser-seal welded, and pressurized at PNNL for both in-pile (JOYO reactor, O-arai, Japan) and out-of-pile creep testing. The objective of this test campaign was to evaluate the creep behavior of primary cladding and structural alloys under consideration for the Prometheus space reactor. PNNL successfully developed electron beam weld parameters for six of these materials prior to the termination of the Navalmore » Reactors program effort to deliver a space reactor for Project Prometheus. These materials were FS-85, ASTAR-811C, T-111, Alloy 617, Haynes 230, and Nirnonic PE16. Early termination of the NR space program precluded the development of laser welding parameters for post-pressurization seal weldments.« less

  8. U. S. Department of Energy (DOE) Industrial Programs and Their Impacts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Weakley, Steven A.; Roop, Joseph M.

    The U.S. Department of Energy's Industrial Technologies Program (ITP) has been working with industry since 1976 to encourage the development and adoption of new, energy-efficient technologies. ITP has helped industry not only use energy and materials more efficiently but also improve environmental performance, product quality, and productivity. To help ITP determine the impacts of its programs, Pacific Northwest National Laboratory (PNNL) periodically reviews and analyzes ITP program benefits. PNNL contacts vendors and users of ITP-sponsored technologies that have been commercialized, estimates the number of units that have penetrated the market, conducts engineering analyses to estimate energy savings from the newmore » technologies, and estimates air pollution and carbon emission reductions. This paper discusses the results of the most recent PNNL review (conducted in 2003). From 1976-2002, the commercialized technologies from ITP's R&D programs and other activities have cumulatively saved 3.7 quadrillion Btu, with a net cost savings of $14.6 billion.« less

  9. U.S. Department of Energy (DOE) Industrial Programs and Their Impacts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Weakley, Steven A.; Roop, Joseph M.

    The U.S. Department of Energy’s Industrial Technologies Program (ITP) has been working with industry since 1976 to encourage the development and adoption of new, energy-efficient technologies. ITP has helped industry not only use energy and materials more efficiently but also improve environmental performance, product quality, and productivity. To help ITP determine the impacts of its programs, Pacific Northwest National Laboratory (PNNL) periodically reviews and analyzes ITP program benefits. PNNL contacts vendors and users of ITP-sponsored technologies that have been commercialized, estimates the number of units that have penetrated the market, conducts engineering analyses to estimate energy savings from the newmore » technologies, and estimates air pollution and carbon emission reductions. This paper discusses the results of the most recent PNNL review (conducted in 2005). From 1976-2004, the commercialized technologies from ITP’s research and development (R&D) programs and other activities have cumulatively saved 4.72 quadrillion Btu, with a net cost savings of $23.1 billion.« less

  10. 40 CFR 52.1673 - Approval status.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) New York § 52.1673 Approval status. (a) With the exceptions set forth in this section, the Administrator approves the New York State Implementation...

  11. 46 CFR 160.017-21 - Approval tests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Approval tests. 160.017-21 Section 160.017-21 Shipping...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Chain Ladder § 160.017-21 Approval tests. (a) General. Each approval test must be conducted on a ladder of the longest length for which approval has been requested. If...

  12. 46 CFR 160.017-21 - Approval tests.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 6 2014-10-01 2014-10-01 false Approval tests. 160.017-21 Section 160.017-21 Shipping...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Chain Ladder § 160.017-21 Approval tests. (a) General. Each approval test must be conducted on a ladder of the longest length for which approval has been requested. If...

  13. Resistance to synthetic blood penetration of National Institute for Occupational Safety and Health-approved N95 filtering facepiece respirators and surgical N95 respirators

    PubMed Central

    Rengasamy, Samy; Sbarra, Deborah; Nwoko, Julian; Shaffer, Ronald

    2015-01-01

    Background Surgical N95 filtering facepiece respirators (FFRs), certified by the National Institute for Occupational Safety and Health (NIOSH) as a respirator and cleared by the Food and Drug Administration (FDA) as a surgical mask, are often used to protect from the inhalation of infectious aerosols and from splashes/sprays of body fluids in health care facilities. A shortage of respirators can be expected during a pandemic. The availability of surgical N95 FFRs can potentially be increased by incorporating FDA clearance requirements in the NIOSH respirator approval process. Methods Fluid resistance of NIOSH-approved N95 FFRs, and FDA-cleared surgical N95 FFRs and surgical masks was tested using the ASTM F1862 method at 450 and 635 cm/sec velocities and compared with the results from a third-party independent laboratory. Blood penetration through different layers of filter media of masks were also analyzed visually. Results Four N95 FFR models showed no test failures at both velocities. The penetration results obtained in the NIOSH laboratory were comparable to those from the third-party independent laboratory. The number of respirator samples failing the test increased with increasing test velocity. Conclusions The results indicate that several NIOSH-approved N95 FFR models would likely pass FD clearance requirements for resistance to synthetic blood penetration. PMID:26231551

  14. 33 CFR 67.10-35 - Notice of approval and withdrawal of approval.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Notice of approval and withdrawal of approval. 67.10-35 Section 67.10-35 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY AIDS TO NAVIGATION AIDS TO NAVIGATION ON ARTIFICIAL ISLANDS AND FIXED STRUCTURES General...

  15. 33 CFR 67.10-35 - Notice of approval and withdrawal of approval.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Notice of approval and withdrawal of approval. 67.10-35 Section 67.10-35 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY AIDS TO NAVIGATION AIDS TO NAVIGATION ON ARTIFICIAL ISLANDS AND FIXED STRUCTURES General...

  16. Laboratory Performance Evaluation Report of SEL 421 Phasor Measurement Unit

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huang, Zhenyu; faris, Anthony J.; Martin, Kenneth E.

    2007-12-01

    PNNL and BPA have been in close collaboration on laboratory performance evaluation of phasor measurement units for over ten years. A series of evaluation tests are designed to confirm accuracy and determine measurement performance under a variety of conditions that may be encountered in actual use. Ultimately the testing conducted should provide parameters that can be used to adjust all measurements to a standardized basis. These tests are performed with a standard relay test set using recorded files of precisely generated test signals. The test set provides test signals at a level and in a format suitable for input tomore » a PMU that accurately reproduces the signals in both signal amplitude and timing. Test set outputs are checked to confirm the accuracy of the output signal. The recorded signals include both current and voltage waveforms and a digital timing track used to relate the PMU measured value with the test signal. Test signals include steady-state waveforms to test amplitude, phase, and frequency accuracy, modulated signals to determine measurement and rejection bands, and step tests to determine timing and response accuracy. Additional tests are included as necessary to fully describe the PMU operation. Testing is done with a BPA phasor data concentrator (PDC) which provides communication support and monitors data input for dropouts and data errors.« less

  17. Concerns regarding a new culture method for Borrelia burgdorferi not approved for the diagnosis of Lyme disease.

    PubMed

    Nelson, Christina; Hojvat, Sally; Johnson, Barbara; Petersen, Jeannine; Schriefer, Marty; Beard, C Ben; Petersen, Lyle; Mead, Paul

    2014-04-18

    In 2005, CDC and the Food and Drug Administration (FDA) issued a warning regarding the use of Lyme disease tests whose accuracy and clinical usefulness have not been adequately established. Often these are laboratory-developed tests (also known as "home brew" tests) that are manufactured and used within a single laboratory and have not been cleared or approved by FDA. Recently, CDC has received inquiries regarding a laboratory-developed test that uses a novel culture method to identify Borrelia burgdorferi, the spirochete that causes Lyme disease. Patient specimens reportedly are incubated using a two-step pre-enrichment process, followed by immunostaining with or without polymerase chain reaction (PCR) analysis. Specimens that test positive by immunostaining or PCR are deemed "culture positive". Published methods and results for this laboratory-developed test have been reviewed by CDC. The review raised serious concerns about false-positive results caused by laboratory contamination and the potential for misdiagnosis.

  18. 49 CFR 451.3 - Action by Approval Authority.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of Existing Containers § 451.3 Action by Approval Authority. (a) The Approval Authority (or the Chief, Office of... affix a safety approval plate to each container after an examination of each container concerned has...

  19. 49 CFR 451.3 - Action by Approval Authority.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of Existing Containers § 451.3 Action by Approval Authority. (a) The Approval Authority (or the Chief, Office of... affix a safety approval plate to each container after an examination of each container concerned has...

  20. 49 CFR 451.3 - Action by Approval Authority.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of Existing Containers § 451.3 Action by Approval Authority. (a) The Approval Authority (or the Chief, Office of... affix a safety approval plate to each container after an examination of each container concerned has...

  1. 49 CFR 451.3 - Action by Approval Authority.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of Existing Containers § 451.3 Action by Approval Authority. (a) The Approval Authority (or the Chief, Office of... affix a safety approval plate to each container after an examination of each container concerned has...

  2. 49 CFR 451.3 - Action by Approval Authority.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of Existing Containers § 451.3 Action by Approval Authority. (a) The Approval Authority (or the Chief, Office of... affix a safety approval plate to each container after an examination of each container concerned has...

  3. Geomorphic Modeling of Macro-Tidal Embayment with Extensive Tidal Flats: Skagit Bay, Washington

    DTIC Science & Technology

    2011-09-30

    tidal flats: Skagit Bay , Washington Lyle Hibler Battelle-Pacific Northwest Division Marine Sciences Laboratory Sequim , WA 98382 phone: (360) 681...3616 fax: (360) 681-4559 email: lyle.hibler@pnnl.gov Adam Maxwell Battelle-Pacific Northwest Division Marine Sciences Laboratory Sequim , WA...Geomorphic modeling of macro-tidal embayment with extensive tidal flats: Skagit Bay , Washington 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT

  4. Total Copper Analyzer for Rapid In Situ Characterization of Effluent Discharges

    DTIC Science & Technology

    2008-08-01

    Building 345 Airdrome Road Wahiawa, HI 96786 SBWWTP operations superintendent Linda Bingler Battelle Sequim Operations PNNL 1529 West Sequim Bay ...concentration measurements by ICP-MS at the Battelle Marine Sciences Laboratory in Sequim , Washington, and a second sample was sent for analysis by GFAA...Road Sequim , WA 98382 Commercial laboratory liaison Steve West Orion Research, Inc. 500 Cummings Center Beverly, MA 01915 Industry partner A

  5. Chemical Composition Analysis and Product Consistency Tests of the ORP Phase 5 Nepheline Study Glasses

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fox, K. M.; Edwards, T. B.; Caldwell, M. E.

    In this report, the Savannah River National Laboratory (SRNL) provides chemical analyses and Product Consistency Test (PCT) results for a series of simulated high-level waste glass compositions fabricated by the Pacific Northwest National Laboratory (PNNL). These data will be used in the development of improved models for the prediction of nepheline crystallization in support of the Hanford Tank Waste Treatment and Immobilization Plant (WTP).

  6. Point-Counterpoint: The FDA Has a Role in Regulation of Laboratory-Developed Tests.

    PubMed

    Caliendo, Angela M; Hanson, Kimberly E

    2016-04-01

    Since the Food and Drug Administration (FDA) released its draft guidance on the regulation of laboratory-developed tests (LDTs) in October 2014, there has been a flurry of responses from commercial and hospital-based laboratory directors, clinicians, professional organizations, and diagnostic companies. The FDA defines an LDT as an "in vitrodiagnostic device that is intended for clinical use and is designed, manufactured, and used within a single laboratory." The draft guidance outlines a risk-based approach, with oversight of high-risk and moderate-risk tests being phased in over 9 years. High-risk tests would be regulated first and require premarket approval. Subsequently, moderate-risk tests would require a 510(k) premarket submission to the FDA and low-risk tests would need only to be registered. Oversight discretion would be exercised for LDTs focused on rare diseases (defined as fewer than 4,000 tests, not cases, per year nationally) and unmet clinical needs (defined as those tests for which there is no alternative FDA-cleared or -approved test). There was an open comment period followed by a public hearing in early January of 2015, and we are currently awaiting the final decision regarding the regulation of LDTs. Given that LDTs have been developed by many laboratories and are essential for the diagnosis and monitoring of an array of infectious diseases, changes in their regulation will have far-reaching implications for clinical microbiology laboratories. In this Point-Counterpoint, Angela Caliendo discusses the potential benefits of the FDA guidance for LDTs whereas Kim Hanson discusses the concerns associated with implementing the guidance and why these regulations may not improve clinical care. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  7. Marcus Theory of Ion-Pairing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Roy, Santanu; Baer, Marcel D.; Mundy, Christopher J.

    We present a theory for ion pair dissociation and association, motivated by the concepts of the Marcus theory of electron transfer. Despite the extensive research on ion-pairing in many chemical and biological processes, much can be learned from the exploration of collective reaction coordinates. To this end, we explore two reaction coordinates, ion pair distance and coordination number. The study of the correlation between these reaction coordinates provides a new insight into the mechanism and kinetics of ion pair dissociation and association in water. The potential of mean force on these 2D-surfaces computed from molecular dynamics simulations of different monovalentmore » ion pairs reveal a Marcus-like mechanism for ion-pairing: Water molecules rearrange forming an activated coordination state prior to ion pair dissociation or association, followed by relaxation of the coordination state due to further water rearrangement. Like Marcus theory, we find the existence of an inverted region where the transition rates are slower with increasing exergonicity. This study provides a new perspective for the future investigations of ion-pairing and transport. SR, CJM, and GKS were supported by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences, and Biosciences. MDB was supported by MS3 (Materials Synthesis and Simulation Across Scales) Initiative, a Laboratory Directed Research and Development Program at Pacific Northwest National Laboratory (PNNL). The research was performed using PNNL Institutional Computing. PNNL is a multi-program national laboratory operated by Battelle for the U.S. Department of Energy.« less

  8. Recharge Data Package for Hanford Single-Shell Tank Waste Management Areas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fayer, Michael J.; Keller, Jason M.

    2007-09-24

    Pacific Northwest National Laboratory (PNNL) assists CH2M HILL Hanford Group, Inc., in its preparation of the Resource Conservation and Recovery Act (RCRA) Facility Investigation report. One of the PNNL tasks is to use existing information to estimate recharge rates for past and current conditions as well as future scenarios involving cleanup and closure of tank farms. The existing information includes recharge-relevant data collected during activities associated with a host of projects, including those of RCRA, the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), the CH2M HILL Tank Farm Vadose Zone Project, and the PNNL Remediation and Closure Science Project.more » As new information is published, the report contents can be updated. The objective of this data package was to use published data to provide recharge estimates for the scenarios being considered in the RCRA Facility Investigation. Recharge rates were estimated for areas that remain natural and undisturbed, areas where the vegetation has been disturbed, areas where both the vegetation and the soil have been disturbed, and areas that are engineered (e.g., surface barrier). The recharge estimates supplement the estimates provided by PNNL researchers in 2006 for the Hanford Site using additional field measurements and model analysis using weather data through 2006.« less

  9. Metering Plan: Intelligent Operational Strategies Through Enhanced Metering Systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pope, Jason E.

    The Sustainability Program at Pacific Northwest National Laboratory (PNNL) has adopted a “triple-bottom-line” approach of environmental stewardship, social responsibility, and economic prosperity to its operations. Metering at PNNL works in support of all three, specifically to measure and inform building energy use and greenhouse gas emissions and minimize water use. The foundation for metering at PNNL is a core goal set, which consists of four objectives: providing accurate data without interruption, analyzing data while it is still new, providing actionable recommendations to operations management, and ensuring PNNL’s compliance with contract metering requirements. These core objectives guide the decisions that wemore » make during annual planning and as we operate throughout the year. This 2016 edition of the Metering Plan conveys the metering practices for and vision of the Sustainability Program. Changes in this plan from the 2015 edition include updated tables and an enhanced discussion on energy tracking systems used at PNNL. This plan also discusses updated benchmarking strategies using PNNL’s graphics and analytics tool, BuildingOS by Lucid Design Group. This plan presents our progress toward the metering goals shared by all federal agencies and highlights our successful completion of metering requirements. Currently, PNNL is fully compliant with the applicable legislative and Executive Order metering requirements. PNNL’s approach to the installation of new meters will be discussed. Perhaps most importantly, this plan details the analysis techniques utilized at PNNL that rely on the endless streams of data newly available as a result of increased meter deployment over the last several years. Previous Metering Plans have documented specific meter connection schemes as PNNL focused on deploying meters in a first step toward managing energy and water use. This plan serves not only to highlight PNNL’s successful completion of agency metering

  10. Naval Research Laboratory Industrial Chemical Analysis and Respiratory Filter Standards Development

    DTIC Science & Technology

    2017-09-29

    Filter Standards Development September 29, 2017 Approved for public release; distribution is unlimited. Thomas E. suTTo Materials and Systems Branch...LIMITATION OF ABSTRACT Naval Research Laboratory Industrial Chemical Analysis and Respiratory Filter Standards Development Thomas E. Sutto Naval Research...approach, developed by NRL, is tested by examining the filter behavior against a number of chemicals to determine if the NRL approach resulted in the

  11. 49 CFR 451.15 - Application for individual approval.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of New Containers § 451.15 Application for individual approval. (a) For approval of new containers... the container. ...

  12. 49 CFR 451.15 - Application for individual approval.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of New Containers § 451.15 Application for individual approval. (a) For approval of new containers... the container. ...

  13. 49 CFR 451.15 - Application for individual approval.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of New Containers § 451.15 Application for individual approval. (a) For approval of new containers... the container. ...

  14. 49 CFR 451.15 - Application for individual approval.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of New Containers § 451.15 Application for individual approval. (a) For approval of new containers... the container. ...

  15. 49 CFR 451.15 - Application for individual approval.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY SAFETY APPROVAL OF CARGO CONTAINERS TESTING AND APPROVAL OF CONTAINERS Approval of New Containers § 451.15 Application for individual approval. (a) For approval of new containers... the container. ...

  16. 30 CFR 7.311 - Approval checklist.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... MINING PRODUCTS TESTING BY APPLICANT OR THIRD PARTY Electric Motor Assemblies § 7.311 Approval checklist. Each motor assembly bearing an MSHA approval marking shall be accompanied by a list of items necessary for maintenance of the motor assembly as approved. ...

  17. 49 CFR 1522.113 - Withdrawal of approval.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY SECURITY RULES FOR ALL MODES OF TRANSPORTATION TSA-APPROVED VALIDATION FIRMS AND VALIDATORS TSA-Approved Validation Firms and Validators for the Certified Cargo Screening Program... TSA-approved validation firm if the validation firm ceases to meet the standards for approval, fails...

  18. 30 CFR 22.10 - Approval plate.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... MINING PRODUCTS PORTABLE METHANE DETECTORS § 22.10 Approval plate. (a) Attachment to be made by manufacturers. (1) Manufacturers shall attach, stamp, or mold an approval plate on each permissible methane... follows: Permissible Methane Detector (or Permissible Methane Indicating Detector) Approval No. ___ issued...

  19. Marketing Approval of Ethical Kampo Medicines.

    PubMed

    Hakamatsuka, Takashi

    2017-01-01

    Kampo medicine is an original traditional medicine in Japan. Currently, 148 ethical Kampo formulations (Kampo prescription drugs) are registered in the National Health Insurance Price List. Kampo medicines can be prescribed under the national insurance system, which shows that they are part of conventional medicine in Japan. Japan has a unified drug approval system that does not distinguish between Western and Kampo medicines, and both are subject to the same regulations. The application for the market approval of ethical Kampo medicines is based on the general notification for drugs, i.e., "Handling of Ethical Combination Drugs" in "Precautions Necessary When Applying for Drug Marketing Approval" (Yakushokushinsa Notification No. 1121-12 of November 21, 2014). Furthermore, applications for the market approval of ethical Kampo medicines should follow the Kampo-specific notification of "Handling of Ethical Kampo Medicines" (Yakushin Notification No. 804 of June 25, 1980). Data from comparative studies with standard decoctions must be submitted with approval applications according to Yakushin 2 Notification No. 120 of May 31, 1985. The safety, efficacy, and quality of Kampo medicines are comprehensively assured by the Japanese Pharmacopoeia, Good Manufacturing Practice, Good Agricultural and Collection Practices, marketing approval certificate, approval standard, and pharmacovigilance. I believe that the basic framework for the market approval of ethical Kampo medicines has been established as described above. The key factors for the practical application of superior manufacturing technology and research achievements and the promotion of drug development are the specific guidelines for the approval of drugs of herbal origin.

  20. An Optically Stimulated Luminescence Uranium Enrichment Monitor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miller, Steven D.; Tanner, Jennifer E.; Simmons, Kevin L.

    The Pacific Northwest National Laboratory (PNNL) has pioneered the use of Optically Stimulated Luminescence (OSL) technology for use in personnel dosimetry and high dose radiation processing dosimetry. PNNL has developed and patented an alumina-based OSL dosimeter that is being used by the majority of medical X-ray and imaging technicians worldwide. PNNL has conceived of using OSL technology to passively measure the level of UF6 enrichment by attaching the prototype OSL monitor to pipes containing UF6 gas within an enrichment facility. The prototype OSL UF6 monitor utilizes a two-element approach with the first element open and unfiltered to measure both themore » low energy and high energy gammas from the UF6, while the second element utilizes a 3-mm thick tungsten filter to eliminate the low energy gammas and pass only the high energy gammas from the UF6. By placing a control monitor in the room away from the UF6 pipes and other ionizing radiation sources, the control readings can be subtracted from the UF6 pipe monitor measurements. The ratio of the shielded to the unshielded net measurements provides a means to estimate the level of uranium enrichment. PNNL has replaced the commercially available MicroStar alumina-based dosimeter elements with a composite of polyethylene plastic, high-Z glass powder, and BaFBr:Eu OSL phosphor powder at various concentrations. The high-Z glass was added in an attempt to raise the average “Z” of the composite dosimeter and increase the response. Additionally, since BaFBr:Eu OSL phosphor is optimally excited and emits light at different wavelengths compared to alumina, the commercially available MicroStar reader was modified for reading BaFBr:Eu in a parallel effort to increase reader sensitivity. PNNL will present the design and performance of our novel OSL uranium enrichment monitor based on a combination of laboratory and UF6 test loop measurements. PNNL will also report on the optimization effort to achieve the highest

  1. Pacific Northwest National Laboratory Annual Site Environmental Report for Calendar Year 2012

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Duncan, Joanne P.; Ballinger, Marcel Y.; Fritz, Brad G.

    The PNNL Annual Site Environmental Report for Calendar Year 2012 was prepared pursuant to the requirements of Department of Energy (DOE) Order 231.1B, "Environment, Safety and Health Reporting" to provide a synopsis of calendar year 2012 information related to environmental management performance and compliance efforts. It summarizes site compliance with federal, state, and local environmental laws, regulations, policies, directives, permits, and orders and environmental management performance.

  2. 40 CFR 52.2122 - Approval status.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... sources covered by CTGs issued by the previous January. (b) EPA disapproved South Carolina's generic...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) South Carolina § 52.2122 Approval status. (a) With the exceptions set forth in this subpart, the Administrator approves South Carolina's plans for...

  3. 40 CFR 52.2062 - Plan approvals.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Plan approvals. 52.2062 Section 52.2062... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Pennsylvania § 52.2062 Plan approvals. (a) Emission limitations and related provisions which are established in Pennsylvania plan approvals as federally...

  4. 40 CFR 52.1973 - Approval of plans.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oregon § 52.1973 Approval of plans. (a) Carbon monoxide. (1) EPA approves as a revision to the Oregon State Implementation Plan, the Second... December 27, 2004. (2) EPA approves as a revision to the Oregon State Implementation Plan, the Salem carbon...

  5. 40 CFR 52.1973 - Approval of plans.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oregon § 52.1973 Approval of plans. (a) Carbon monoxide. (1) EPA approves as a revision to the Oregon State Implementation Plan, the Second... December 27, 2004. (2) EPA approves as a revision to the Oregon State Implementation Plan, the Salem carbon...

  6. 40 CFR 52.1973 - Approval of plans.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oregon § 52.1973 Approval of plans. (a) Carbon monoxide. (1) EPA approves as a revision to the Oregon State Implementation Plan, the Second... December 27, 2004. (2) EPA approves as a revision to the Oregon State Implementation Plan, the Salem carbon...

  7. 40 CFR 52.1973 - Approval of plans.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oregon § 52.1973 Approval of plans. (a) Carbon monoxide. (1) EPA approves as a revision to the Oregon State Implementation Plan, the Second... December 27, 2004. (2) EPA approves as a revision to the Oregon State Implementation Plan, the Salem carbon...

  8. 46 CFR 160.176-13 - Approval Tests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Approval Tests. 160.176-13 Section 160.176-13 Shipping...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Inflatable Lifejackets § 160.176-13 Approval Tests. (a) General. (1) This section contains requirements for approval tests and examinations of inflatable lifejackets...

  9. 40 CFR 52.672 - Approval of plans.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Idaho § 52.672 Approval of plans. (a) Carbon Monoxide. (1) EPA approves as a revision to the Idaho State Implementation Plan, the Limited Maintenance Plan for.... [Reserved] (e) Particulate Matter. (1) EPA approves as a revision to the Idaho State Implementation Plan...

  10. Two High-Resolution, Quantitative, Infrared Spectral Libraries for Atmospheric Chemistry

    NASA Astrophysics Data System (ADS)

    Johnson, T. J.; Sharpe, S. W.; Sams, R. L.; Chu, P. M.

    2001-12-01

    The Pacific Northwest National Laboratory (PNNL) and the National Institute of Standards and Technology (NIST) are independently creating quantitative, 0.10 cm-1 resolution, infrared spectral libraries of vapor phase compounds. Both libraries contain many species of use to the gas-phase spectroscopist, including for atmospheric chemistry. The NIST library will consist of approximately 100 vapor phase spectra primarily associated with volatile hazardous air pollutants (HAPs) and suspected greenhouse gases, whereas the PNNL library will consist of approximately 400 vapor phase spectra associated with DOE's remediation mission. Data are being recorded from 600 to 6500 cm-1 to cover not only the classical fingerprint region, but much of the near-infrared as well. The wavelength axis is calibrated against published standards. To prepare the samples, the two laboratories use significantly different sample preparation and handling techniques: NIST uses gravimetric dilution and a continuous flowing sample while PNNL uses partial pressure dilution and a static sample. The data are validated against one another and agreement on the ordinate axis is generally found to be within the statistical uncertainties (2σ ) of the Beer's law fit and less than 3 % of the total integrated band areas for the 4 chemicals used in this comparison. The nature of the two databases and the rigorous nature used to acquire the data will be briefly discussed.

  11. Department of Energy WindSentinel Loan Program Description

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shaw, William J.; Sturges, Mark H.

    The U.S. Department of Energy (DOE) currently owns two AXYS WindSentinel buoys that collect a comprehensive set of meteorological and oceanographic data to support resource characterization for wind energy offshore. The two buoys were delivered to DOE’s Pacific Northwest National Laboratory (PNNL) in September, 2014. After acceptance testing and initial performance testing and evaluation at PNNL’s Marine Sciences Laboratory in Sequim, Washington, the buoys have been deployed off the U.S. East Coast. One buoy was deployed approximately 42 km east of Virginia Beach, Virginia from December, 2014 through June, 2016. The second buoy was deployed approximately 5 km off Atlanticmore » City, New Jersey in November, 2015. Data from the buoys are available to the public. Interested parties can create an account and log in to http://offshoreweb.pnnl.gov. In response to a number of inquiries and unsolicited proposals, DOE’s Wind Energy Technologies Office is implementing a program, to be managed by PNNL, to lend the buoys to qualified parties for the purpose of acquiring wind resource characterization data in areas of interest for offshore wind energy development. This document describes the buoys, the scope of the loans, the process of how borrowers will be selected, and the schedule for implementation of this program, including completing current deployments.« less

  12. 75 FR 48302 - Notice of Request for Extension of Approval of an Information Collection; Credit Account Approval...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-10

    ....gov ). FOR FURTHER INFORMATION CONTACT: For information on credit account approval for reimbursable..., at (301) 851-2908. SUPPLEMENTARY INFORMATION: Title: Credit Account Approval for Reimbursable... Inspection Service [Docket No. APHIS-2010-0071] Notice of Request for Extension of Approval of an Information...

  13. 78 FR 54617 - Notice of Request for Extension of Approval of an Information Collection; Credit Account Approval...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-05

    ...] Notice of Request for Extension of Approval of an Information Collection; Credit Account Approval for... (202) 799-7039 before coming. FOR FURTHER INFORMATION CONTACT: For information on credit account... Coordinator, at (301) 851-2908. SUPPLEMENTARY INFORMATION: Title: Credit Account Approval for Reimbursable...

  14. 40 CFR 52.1772 - Approval status.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) North Carolina § 52.1772 Approval status. (a) With the exceptions set forth in this subpart, the Administrator approves North Carolina's plans for... CTGs issued by the previous January. (b) New Source review permits issued pursuant to section 173 of...

  15. 40 CFR 52.2572 - Approval status.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Wisconsin § 52.2572 Approval status. (a) With the exceptions set forth in this subpart, the Administrator approves Wisconsin's plans for the... Wisconsin. (b) [Reserved] [75 FR 82563, Dec. 30, 2010, as amended at 78 FR 30209, May 22, 2013] ...

  16. 40 CFR 52.2572 - Approval status.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Wisconsin § 52.2572 Approval status. With the exceptions set forth in this subpart, the Administrator approves Wisconsin's plans for the attainment and... schedule contained in the 1982 Ozone SIP revision for Southeastern Wisconsin. [49 FR 8923, Mar. 9, 1984] ...

  17. 40 CFR 52.2572 - Approval status.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Wisconsin § 52.2572 Approval status. (a) With the exceptions set forth in this subpart, the Administrator approves Wisconsin's plans for the... Wisconsin. (b) [Reserved] [75 FR 82563, Dec. 30, 2010, as amended at 78 FR 30209, May 22, 2013] ...

  18. 19 CFR 115.42 - Approval plates.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... CARGO CONTAINER AND ROAD VEHICLE CERTIFICATION PURSUANT TO INTERNATIONAL CUSTOMS CONVENTIONS Procedures for Approval of Containers After Manufacture § 115.42 Approval plates. (a) The owner or operator... plate in the manner specified for containers approved by design type (see § 115.32). (b) Although an...

  19. 19 CFR 115.42 - Approval plates.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... CARGO CONTAINER AND ROAD VEHICLE CERTIFICATION PURSUANT TO INTERNATIONAL CUSTOMS CONVENTIONS Procedures for Approval of Containers After Manufacture § 115.42 Approval plates. (a) The owner or operator... plate in the manner specified for containers approved by design type (see § 115.32). (b) Although an...

  20. 19 CFR 115.42 - Approval plates.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... CARGO CONTAINER AND ROAD VEHICLE CERTIFICATION PURSUANT TO INTERNATIONAL CUSTOMS CONVENTIONS Procedures for Approval of Containers After Manufacture § 115.42 Approval plates. (a) The owner or operator... plate in the manner specified for containers approved by design type (see § 115.32). (b) Although an...

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