Lawrence Livermore National Laboratory safeguards and security quarterly progress report to the US Department of Energy quarter ending September 30, 1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davis, G.; Mansur, D.L.; Ruhter, W.D.

1994-10-01

This report presents the details of the Lawrence Livermore National Laboratory safeguards and securities program. This program is focused on developing new technology, such as x- and gamma-ray spectrometry, for measurement of special nuclear materials. This program supports the Office of Safeguards and Securities in the following five areas; safeguards technology, safeguards and decision support, computer security, automated physical security, and automated visitor access control systems.

Savannah River Ecology Laboratory, annual technical progress report of ecological research for the year ending June 30, 1997

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wein, G.; Rosier, B.

1997-12-31

This report provides an overview of the research programs and program components carried out by the Savannah River Ecology Laboratory. Research focused on the following: advanced analytical and spectroscopic techniques for developing novel waste isolation and stabilization technologies as well as cost-effective remediation strategies; ecologically sound management of damaged and remediation of ecological systems; ecotoxicology, remediation, and risk assessment; radioecology, including dose assessments for plants and animals exposed to environmental radiation; and other research support programs.

FY2017 Technology Integration Annual Progress Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

The 2017 Technology Integration Annual Progress Report covers 27 multi-year projects funded by the Vehicle Technologies Office. The report includes information on 20 competitively awarded projects, ranging from training on alternative fuels and vehicles for first responders, to safety training and design for maintenance facilities housing gaseous fuel vehicles, to electric vehicle community partner programs. It also includes seven projects conducted by several of VTO’s national laboratory partners, Argonne National Laboratory, Oak Ridge National Laboratory and the National Renewable Energy Laboratory. These projects range from a Technical Assistance project for business, industry, government and individuals, to the EcoCar 3 Studentmore » Competition, and the Fuel Economy Information Project.« less

Implementing a resource management program for accreditation process at the medical laboratory.

PubMed

Yenice, Sedef

2009-03-01

To plan for and provide adequate resources to meet the mission and goals of a medical laboratory in compliance with the requirements for laboratory accreditation by Joint Commission International. The related policies and procedures were developed based on standard requirements for resource management. Competency assessment provided continuing education and performance feedback to laboratory employees. Laboratory areas were designed for the efficient and safe performance of laboratory work. A physical environment was built up where hazards were controlled and personnel activities were managed to reduce the risk of injuries. An Employees Occupational Safety and Health Program (EOSHP) was developed to address all types of hazardous materials and wastes. Guidelines were defined to verify that the methods would produce accurate and reliable results. An active resource management program will be an effective way of assuring that systems are in control and continuous improvement is in progress.

Teaching Multi-Level Classes: A Lesson from the Past.

ERIC Educational Resources Information Center

Book, Leon C.

The laboratory school for Southeast Missouri State University offers individualized French and Spanish second language instruction to secondary students by scheduling them together in one multilevel class. Students progress individually and in small groups through planned, self-paced, continuous progress programs. Each student is given a checklist…

The Marin City Early Intervention Report.

ERIC Educational Resources Information Center

Far West Lab. for Educational Research and Development, Berkeley, CA.

This report briefly describes the Marin City, California community and summarizes progress made by the Far West Laboratory's Western Regional Laboratory in the development of a long-range community intervention program. Marin City is a predominantly low-income, black community in which 30 percent of households, mainly those headed by single women,…

Biological and Environmental Research Program at Oak Ridge National Laboratory, FY 1992--1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

This report is the 1992--1994 Program Director's Overview Report for Oak Ridge National Laboratory's (ORNL's) Biological and Environmental Research (BER) Program, and as such it addresses KP-funded work at ORNL conducted during FY 1991 and in progress during FY 1992; it also serves as a planning document for the remainder of FY 1992 through FY 1994. Non-BER funded work at ORNL relevant to the mission of OHER is also discussed. The second section of the report describes ORNL facilities and resources used by the BER program. The third section addresses research management practices at ORNL. The fourth, fifth, and sixthmore » sections address BER-funded research in progress, program accomplishments and research highlights, and program orientation for the remainder of FY 1992 through FY 1994, respectively. Work for non-BER sponsors is described in the seventh section, followed by a discussion of significant near and long-term issues facing BER work at ORNL in the eighth section. The last section provides a statistical summary of BER research at ORNL. Appendices supplement the above topics with additional detail.« less

FY 2005 Annual Progress Report for the DOE Hydrogen Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

In cooperation with industry, academia, national laboratories, and other government agencies, the Department of Energy's Hydrogen Program is advancing the state of hydrogen and fuel cell technologies in support of the President's Hydrogen Fuel Initiative. The initiative seeks to develop hydrogen, fuel cell, and infrastructure technologies needed to make it practical and cost-effective for Americans to choose to use fuel cell vehicles by 2020. Significant progress was made in fiscal year 2005 toward that goal.

1992 Environmental monitoring report, Sandia National Laboratories, Albuquerque, New Mexico

DOE Office of Scientific and Technical Information (OSTI.GOV)

Culp, T.; Cox, W.; Hwang, H.

1993-09-01

This 1992 report contains monitoring data from routine radiological and nonradiological environmental surveillance activities. summaries of significant environmental compliance programs in progress, such as National Environmental Policy Act documentation, environmental permits, envirorunental restoration, and various waste management programs for Sandia National Laboratories in Albuquerque, New Mexico, are included. The maximum offsite dose impact was calculated to be 0.0034 millirem. The total population within a 50-mile radius of Sandia National Laboratories/New Mexico received an estimated collective dose of 0.019 person-rem during 1992 from the laboratories` operations. As in the previous year, the 1992 operations at Sandia National Laboratories/New Mexico had nomore » discernible impact on the general public or on the environment.« less

New Brunswick Laboratory: Progress report, October 1993 through September 1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The mission of the New Brunswick Laboratory of the US Department of Energy (DOE) is to serve as the National Certifying Authority for nuclear reference materials and to provide an independent Federal technical staff and laboratory resource performing nuclear material measurement, safeguards and non-proliferation functions in support of multiple program sponsors. During FY 94 New Brunswick Laboratory (NBL) completed development of a Strategic Plan which will aid in better defining performance oriented laboratory goals and objectives in each functional area consistent with the changing needs of the global nuclear community. This annual report describes accomplishments achieved in carrying out NBL`smore » assigned missions. Details of completed projects are reported in separate topical reports or as open-literature publications. Programs discussed here are: (1) safeguards assistance; (2) reference materials program; (3) measurement evaluation; (4) measurement services; and (5) measurement development.« less

2012 Wind Program Peer Review Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zayas, Jose; Higgins, Mark

2012-06-01

This report summarizes the proceedings of the 2012 Wind Program Peer Review, the goals of which were to review and evaluate the strategy and goals of the Wind Program; review and evaluate the progress and accomplishments of the program's projects funded in fiscal year (FY) 2010 and FY 2011; and foster interactions among the national laboratories, industry, and academic institutions conducting research and development on behalf of the program.

1996 Laboratory directed research and development annual report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meyers, C.E.; Harvey, C.L.; Lopez-Andreas, L.M.

This report summarizes progress from the Laboratory Directed Research and Development (LDRD) program during fiscal year 1996. In addition to a programmatic and financial overview, the report includes progress reports from 259 individual R&D projects in seventeen categories. The general areas of research include: engineered processes and materials; computational and information sciences; microelectronics and photonics; engineering sciences; pulsed power; advanced manufacturing technologies; biomedical engineering; energy and environmental science and technology; advanced information technologies; counterproliferation; advanced transportation; national security technology; electronics technologies; idea exploration and exploitation; production; and science at the interfaces - engineering with atoms.

The Telecommunications and Data Acquisition Progress Report 42-123

NASA Technical Reports Server (NTRS)

Yuen, Joseph H. (Editor)

1995-01-01

The progress of research programs monitored by the Jet Propulsion Laboratory's Telecommunications and Mission Operations Directorate (TMOD) are presented in this quarterly document. Areas monitored include space communications, radio navigation, radio science, ground-based radio and radar astronomy, information systems, and all other communication and research technology activities for the Deep Space Network (DSN).

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boparai, A. S.; Bowers, D. L.; Graczyk, D. G.

This report summarizes the activities of the Analytical Chemistry Laboratory (ACL) at Argonne National Laboratory (ANL) for Fiscal Year (FY) 1998 (October 1997 through September 1998). This annual progress report, which is the fifteenth in this series for the ACL, describes effort on continuing projects, work on new projects, and contributions of the ACL staff to various programs at ANL.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Green, D. W.; Boparai, A. S.; Bowers, D. L.

This report summarizes the activities of the Analytical Chemistry Laboratory (ACL) at Argonne National Laboratory (ANL) for Fiscal Year (FY) 1999 (October 1998 through September 1999). This annual progress report, which is the sixteenth in this series for the ACL, describes effort on continuing projects, work on new projects, and contributions of the ACL staff to various programs at ANL.

New Brunswick Laboratory progress report, October 1994--September 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The mission of the New Brunswick Laboratory (NBL) of the A. S. Department of Energy (DOE) is to serve as the National Certifying Authority for nuclear reference materials and to provide an independent Federal technical staff and laboratory resource performing nuclear material measurement, safeguards, and non-proliferation functions in support of multiple program sponsors. This annual report describes accomplishments achieved in carrying out NBL`s assigned missions.

Internal quality control indicators of cervical cytopathology exams performed in laboratories monitored by the External Quality Control Laboratory.

PubMed

Ázara, Cinara Zago Silveira; Manrique, Edna Joana Cláudio; Tavares, Suelene Brito do Nascimento; de Souza, Nadja Lindany Alves; Amaral, Rita Goreti

2014-09-01

To evaluate the impact of continued education provided by an external quality control laboratory on the indicators of internal quality control of cytopathology exams. The internal quality assurance indicators for cytopathology exams from 12 laboratories monitored by the External Quality Control Laboratory were evaluated. Overall, 185,194 exams were included, 98,133 of which referred to the period preceding implementation of a continued education program, while 87,061 referred to the period following this intervention. Data were obtained from the Cervical Cancer Database of the Brazilian National Health Service. Following implementation of the continued education program, the positivity index (PI) remained within recommended limits in four laboratories. In another four laboratories, the PI progressed from below the limits to within the recommended standards. In one laboratory, the PI remained low, in two laboratories, it remained very low, and in one, it increased from very low to low. The percentage of exams compatible with a high-grade squamous intraepithelial lesion (HSIL) remained within the recommended limits in five laboratories, while in three laboratories it progressed from below the recommended levels to >0.4% of the total number of satisfactory exams, and in four laboratories it remained below the standard limit. Both the percentage of atypical squamous cells of undetermined significance (ASC-US) in relation to abnormal exams, and the ratio between ASC-US and intraepithelial lesions remained within recommended levels in all the laboratories investigated. An improvement was found in the indicators represented by the positivity index and the percentage of exams compatible with a high-grade squamous intraepithelial lesion, showing that the role played by the external quality control laboratory in providing continued education contributed towards improving laboratory staff skills in detecting cervical cancer precursor lesions.

Space nuclear safety program. Progress report, October-December 1984

DOE Office of Scientific and Technical Information (OSTI.GOV)

George, T.G.

1986-05-01

This quarterly report covers studies related to the use of /sup 238/PuO/sub 2/ in radioisotope power systems carried out for the Office of Special Nuclear Projects of the US Department of Energy by Los Alamos National Laboratory. Most of the studies discussed are ongoing; the results and conclusions described may change as the work progresses.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Green, D.W.; Boparai, A.S.; Bowers, D.L.

The purpose of this report is to summarize the activities of the Analytical Chemistry Laboratory (ACL) at Argonne National Laboratory (ANL) for Fiscal Year (FY) 1997 (October 1996 through September 1997). This annual progress report is the fourteenth in this series for the ACL, and it describes continuing effort on projects, work on new projects, and contributions of the ACL staff to various programs at ANL.

LLE 1998 annual report, October 1997--September 1998. Inertial fusion program and National Laser Users` Facility program

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1999-01-01

This report summarizes research at the Laboratory for Laser Energetics (LLE), the operation of the National Laser Users` Facility (NLUF), and programs involving the education of high school, undergraduate, and graduate students for FY98. Research summaries cover: progress in laser fusion; diagnostic development; laser and optical technology; and advanced technology for laser targets.

Pacific Northwest Laboratory annual report for 1979 to the DOE Assistant Secretary for Environment. Part 5. Environmental assessment, control, health, and safety

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baalman, R.W.; Dotson, C.W.

1980-02-01

Part 5 of the 1979 Annual Report to the Department of Energy Assistant Secretary for the Environment presents Pacific Northwest Laboratory's progress on work performed for the Office of Technology Impacts, the Office of Environmental Compliance and Overview, and the Office of Health and Environmental Research. The report is in four sections, corresponding to the program elements: technology impacts, environmental control engineering, operational and environmental compliance, and human health studies. In each section, articles describe progress made during FY 1979 on individual projects.

The Submillimeter-wave Rotational Spectra of Interstellar Molecules

NASA Technical Reports Server (NTRS)

Herbst, Eric; DeLucia, Frank C.; Butler, R. A. H.; Winnewisser, M.; Winnewisser, G.; Fuchs, U.; Groner, P.; Sastry, K. V. L. N.

2002-01-01

We discuss past and recent progress in our long-term laboratory program concerning the submillimeter-wave rotational spectroscopy of known and likely interstellar molecules, especially those associated with regions of high-mass star formation. Our program on the use of spectroscopy to study rotationally inelastic collisions of interstellar interest is also briefly mentioned.

Evidence Based Education Request Desk. EBE #755

ERIC Educational Resources Information Center

Regional Educational Laboratory Southeast, 2010

2010-01-01

The Bill and Melinda Gates Foundation created the Early College High School Initiative in 2002, opening more than 200 hundred early college programs across the nation and every year a new report is created to evaluate the progress of the program (Berger, Adelman, & Cole, 2010). Staff at the Regional Educational Laboratory Southeast (REL-SE)…

Space nuclear safety program

NASA Astrophysics Data System (ADS)

George, T. G.

1990-02-01

This quarterly report describes studies related to the use of Pu(238)O sub 2 in radioisotope power systems, carried out of the Office of Defense Energy Programs and Special Applications of the U.S. Department of Energy by Los Alamos National Laboratory. The studies are ongoing; the results and conclusions described may change as the work progresses.

University of Illinois at Urbana-Champaign, Materials Research Laboratory progress report for FY 1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-07-01

This interdisciplinary laboratory in the College of Engineering support research in areas of condensed matter physics, solid state chemistry, and materials science. These research programs are developed with the assistance of faculty, students, and research associates in the departments of Physics, Materials Science and Engineering, chemistry, Chemical Engineering, Electrical Engineering, Mechanical Engineering, and Nuclear Engineering.

Chemistry Research

NASA Technical Reports Server (NTRS)

1987-01-01

Philip Morris research center scientists use a computer program called CECTRP, for Chemical Equilibrium Composition and Transport Properties, to gain insight into the behavior of atoms as they progress along the reaction pathway. Use of the program lets the scientist accurately predict the behavior of a given molecule or group of molecules. Computer generated data must be checked by laboratory experiment, but the use of CECTRP saves the researchers hundreds of hours of laboratory time since experiments must run only to validate the computer's prediction. Philip Morris estimates that had CECTRP not been available, at least two man years would have been required to develop a program to perform similar free energy calculations.

California Energy Systems for the 21st Century 2016 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Van Randwyk, J.; Boutelle, A.; McClelland, C.

The California Energy Systems for the 21st Century (CES-21) Program is a public-private collaborative research and development program between the California Joint Utilities1 and Lawrence Livermore National Laboratory (LLNL). The purpose of this annual report is to provide the California Public Utilities Commission (CPUC or Commission) with a summary of the 2016 progress of the CES-21 Program.

Dental laboratory technology education in China: current situation and challenges.

PubMed

Zheng, Liwei; Yue, Li; Zhou, Min; Yu, Haiyang

2013-03-01

Modern dentistry and dental education in China were first introduced from abroad by Dr. Lindsay in 1907. However, advancements in the field of dental laboratory technology did not occur to the same degree in specialties such as prosthodontics and orthodontics. Since the 1990s, orders from abroad demanding dental appliances surged as the image of China as the "world's factory" strengthened. The assembly line model, in which technicians work like simple procedure workers, was rapidly applied to denture production, while the traditional education system and apprenticeship systems demonstrated little progress in these years. The lack of advancement in dental laboratory technology education caused insufficient development in China's dental technology industry. In order to alter the situation, a four-year dental laboratory technology undergraduate educational program was established in 2005 by West China School of Stomatology, Sichuan University (WCSS, SCU). This program was based on SCU's undergraduate education and WCSS's junior college education systems. The program introduced scientific methods in relevant subjects into laboratory technicians' training and made many improvements in the availability of trained faculty, textbooks, laboratory facilities, and curriculum.

2014 Wind Program Peer Review Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

none,

The Wind Program Peer Review Meeting was held March 24-28, 2014 in Arlington, VA. Principle investigators from the Energy Department, National Laboratories, academic, and industry representatives presented the progress of their DOE-funded research. This report documents the formal, rigorous evaluation process and findings of nine independent reviewers who examined the technical, scientific, and business results of Wind Program funded projects, as well as the productivity and management effectiveness of the Wind Program itself.

Development and evaluation of a computer program to grade student performance on peripheral blood smears

NASA Astrophysics Data System (ADS)

Lehman, Donald Clifford

Today's medical laboratories are dealing with cost containment health care policies and unfilled laboratory positions. Because there may be fewer experienced clinical laboratory scientists, students graduating from clinical laboratory science (CLS) programs are expected by their employers to perform accurately in entry-level positions with minimal training. Information in the CLS field is increasing at a dramatic rate, and instructors are expected to teach more content in the same amount of time with the same resources. With this increase in teaching obligations, instructors could use a tool to facilitate grading. The research question was, "Can computer-assisted assessment evaluate students in an accurate and time efficient way?" A computer program was developed to assess CLS students' ability to evaluate peripheral blood smears. Automated grading permits students to get results quicker and allows the laboratory instructor to devote less time to grading. This computer program could improve instruction by providing more time to students and instructors for other activities. To be valuable, the program should provide the same quality of grading as the instructor. These benefits must outweigh potential problems such as the time necessary to develop and maintain the program, monitoring of student progress by the instructor, and the financial cost of the computer software and hardware. In this study, surveys of students and an interview with the laboratory instructor were performed to provide a formative evaluation of the computer program. In addition, the grading accuracy of the computer program was examined. These results will be used to improve the program for use in future courses.

LLE 2009 annual report, October 2008-September 2009

DOE Office of Scientific and Technical Information (OSTI.GOV)

none, none

2010-01-01

The fiscal year ending September 2009 (FY2009) concluded the second year of the third five-year renewal of Cooperative Agreement DE-FC52-08NA28302 with the U.S. Department of Energy (DOE). This annual report summarizes progress in inertial fusion research at the Laboratory for Laser Energetics (LLE) during the past fiscal year. It also reports on LLE’s progress on laboratory basic science research; laser, optical materials, and advanced technology development; operation of OMEGA and OMEGA EP for the National Laser Users’ Facility (NLUF), and other external users; and programs focusingon the education of high school, undergraduate, and graduate students during the year.

Laboratory directed research and development annual report 2004.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

This report summarizes progress from the Laboratory Directed Research and Development (LDRD) program during fiscal year 2004. In addition to a programmatic and financial overview, the report includes progress reports from 352 individual R and D projects in 15 categories. The 15 categories are: (1) Advanced Concepts; (2) Advanced Manufacturing; (3) Biotechnology; (4) Chemical and Earth Sciences; (5) Computational and Information Sciences; (6) Differentiating Technologies; (7) Electronics and Photonics; (8) Emerging Threats; (9) Energy and Critical Infrastructures; (10) Engineering Sciences; (11) Grand Challenges; (12) Materials Science and Technology; (13) Nonproliferation and Materials Control; (14) Pulsed Power and High Energy Densitymore » Sciences; and (15) Corporate Objectives.« less

US Army Medical Bioengineering Research and Development Laboratory Annual Progress Report for FY 84. Volume 1

DTIC Science & Technology

1984-10-01

develop pollution abatement procedures for Army munition plants and military installations.n, t ftr Laboratory is also actively engaged in the...FACILITIES The physical plant provides over 100,000 square feet for research, development, testing, and administrative activities . Space is...protection of industrial workers and thq surrounding community at Army-controlled, industry-operated munition plants . G Environmental Quality program

Hybrid magnet program at the Francis Bitter National Magnet Laboratory MIT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leupold, M.J.; Weggel, R.J.

1992-01-01

Resistive water-cooled magnets can generate field according to how much power is available. The authors have developed the hybrid concept for generating fields beyond a power limit, up to 45 T. Along the way the authors have progressed through five successively more adventurous designs. This paper chronicles the evolution of hybrid magnets built at the Francis Bitter National Magnet Laboratory.

Astronomy Applications of Adaptive Optics at Lawrence Livermore National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bauman, B J; Gavel, D T

2003-04-23

Astronomical applications of adaptive optics at Lawrence Livermore National Laboratory (LLNL) has a history that extends from 1984. The program started with the Lick Observatory Adaptive Optics system and has progressed through the years to lever-larger telescopes: Keck, and now the proposed CELT (California Extremely Large Telescope) 30m telescope. LLNL AO continues to be at the forefront of AO development and science.

DOE Office of Scientific and Technical Information (OSTI.GOV)

French, T

I am pleased to present the fiscal year 2007 Laboratory Directed Research and Development (LDRD) annual report. This represents the first year that SRNL has been eligible for LDRD participation and our results to date demonstrate we are off to an excellent start. SRNL became a National Laboratory in 2004, and was designated the 'Corporate Laboratory' for the DOE Office of Environmental Management (EM) in 2006. As you will see, we have made great progress since these designations. The LDRD program is one of the tools SRNL is using to enable achievement of our strategic goals for the DOE. Themore » LDRD program allows the laboratory to blend a strong basic science component into our applied technical portfolio. This blending of science with applied technology provides opportunities for our scientists to strengthen our capabilities and delivery. The LDRD program is vital to help SRNL attract and retain leading scientists and engineers who will help build SRNL's future and achieve DOE mission objectives. This program has stimulated our research staff creativity, while realizing benefits from their participation. This investment will yield long term dividends to the DOE in its Environmental Management, Energy, and National Security missions.« less

Metal hydride reasearch and development program at Brookhaven National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, J.R.; Reilly, J.J.

1978-01-01

A progress report is presented covering work performed in the hydrogen materials development program at Brookhaven National Laboratory (BNL) for FY78 which encompasses the time period from October 1, 1977 through September 30, 1978. The subjects to be discussed here concern properties of importance in the utilization of metal hydrides as energy storage media. Most of the areas of research were initiated prior to FY78, however all of the results contained in this manuscript were obtained during the aforementioned period of time. The following subjects will be discussed: the properties of ferro-titanium and chrome-titanium alloy hydrides.

Quarterly Progress Report (January 1 to March 31, 1950)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brookhaven National Laboratory

This is the first of a series of Quarterly Reports. These reports will deal primarily with the progress made in our scientific program during a three months period. Those interested in matters pertaining to organization, administration, complete scientific program, personnel and other matters not directly involved in current scientific progress are referred to our Annual Progress Report which is issued in January. We have attempted to describe new information that appears significant, or of interest, to other scientists within the Atomic Energy Commission Laboratories. No effort has been made, however, to detail progress in each and every research project. Littlemore » or no reference will therefore be found to the projects in which progress during the current period is considered too inconclusive. Since our organizational structure is departmental, the work described herein is arranged in the following sequence: (1) Accelerator Project; (2) Biology Department; (3) Chemistry Department; (4) Instrumentation and Health Physic8 Department; (5) Medical Department; (6) Physics Department; and (7) Reactor Science and Engineering Department.« less

Advanced ion trap structures with integrated tools for qubit manipulation

NASA Astrophysics Data System (ADS)

Sterk, J. D.; Benito, F.; Clark, C. R.; Haltli, R.; Highstrete, C.; Nordquist, C. D.; Scott, S.; Stevens, J. E.; Tabakov, B. P.; Tigges, C. P.; Moehring, D. L.; Stick, D.; Blain, M. G.

2012-06-01

We survey the ion trap fabrication technologies available at Sandia National Laboratories. These include four metal layers, precision backside etching, and low profile wirebonds. We demonstrate loading of ions in a variety of ion traps that utilize these technologies. Additionally, we present progress towards integration of on-board filtering with trench capacitors, photon collection via an optical cavity, and integrated microwave electrodes for localized hyperfine qubit control and magnetic field gradient quantum gates. [4pt] This work was supported by Sandia's Laboratory Directed Research and Development (LDRD) Program and the Intelligence Advanced Research Projects Activity (IARPA). Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the US Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000.

Communication Sciences Laboratory Quarterly Progress Report, Volume 9, Number 3: Research Programs of Some of the Newer Members of CSL.

ERIC Educational Resources Information Center

Feinstein, Stephen H.; And Others

The research reported in these papers covers a variety of communication problems. The first paper covers research on sound navigation by the blind and involves echo perception research and relevant aspects of underwater sound localization. The second paper describes a research program in acoustic phonetics and concerns such related issues as…

Joint Services Electronics Program.

DTIC Science & Technology

1980-05-01

STATEMMEN A Approved for public release, COD Distribution Unlimited.99 Joint Services Electronics Program* _-ANNUAL PROGRESS RP O. 93) 7 / Covering Period...and the temperature dependence of that (dispersive transport) trap limited mobility has shown interesting new effects. Publications of the Research...Low-Cost Laboratory Computer Interface System," (Scheduled for publication May, 1980, Review ot Scinti’i3 Instruments). | i III. INFORMATION

New Brunswick Laboratory progress report, October 1989--September 1990

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The New Brunswick Laboratory (NBL) has been tasked by the DOE Office of Safeguards and Security, Defense Programs (OSS/DP) to assure the application of accurate and reliable measurement technology for the safeguarding of special nuclear materials. NBL is fulfilling its mission responsibilities by identifying the measurement and measurement-related needs of the nuclear material safeguards community and addressing them by means of activities in the following program areas: (1) reference and calibration materials, (2) measurement development, (3) measurement services, (4) measurement evaluation, (5) safeguards assessment, and (6) site-specific assistance. Highlights of each of these program areas are provided in this summary.more » This progress report is written as a part of NBL's technology transfer responsibilities, primarily for the use and benefit of the scientific personnel that perform safeguards-related measurements. Consequently, the report is technical in nature. Many of the reports of multi-year projects are fragmentary in that only partial results are reported. Separate topical reports are to be issued at the completion of many of these projects. 30 refs.« less

Transuranic solid waste management programs. Progress report, July--December 1975

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1976-09-01

Progress is reported for three transuranic solid waste management programs funded at the Los Alamos Scientific Laboratory (LASL) by the Energy Research and Development Administration (ERDA) Division of Fuel Cycle and Production (NFCP). Under the Transuranic Waste Research and Development Program, continued studies have shown the potential attractiveness of fiber drums as an acceptable substitute for the current mild steel storage containers. Various fire retardants have been evaluated, with one indicating significant ability to inhibit fire propagation. Continued radiolysis studies, under laboratory and field conditions, continue to reaffirm earlier LASL results indicating no significant hazard from radiolytic reactions, assuming nomore » change in current allowable loadings. Care must be exercised to differentiate between radiolytic and chemical reactions. Other efforts have identified a modification of chemical processing to reduce the amounts of plutonium requiring retrievable storage. Studies are also in progress to enhance the sensitivity of the LASL MEGAS assay system. The Transuranic-Contaminated Solid Waste Treatment Development Facility building was 72 percent complete as of December 31, 1975, which is in accord with the existing schedule. Procurement of process components is also on schedule. Certain modifications to the facility have been made, and various pre-facility experiments on waste container handling and processing have been completed. The program for the Evaluation of Transuranic-Contaminated Radioactive Waste Disposal Areas continued development of various computer modules for simulation of radionuclide transport within the biosphere. In addition, program staff contributed to an ERDA document on radioactive waste management through the preparation of a report on burial of radioactive waste at ERDA-contractor and commercial sites.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Campbell, J.A.; Clauss, S.A.; Grant, K.E.

The objectives of this task are to develop and document extraction and analysis methods for organics in waste tanks, and to extend these methods to the analysis of actual core samples to support the Waste Tank organic Safety Program. This report documents progress at Pacific Northwest Laboratory (a) during FY 1994 on methods development, the analysis of waste from Tank 241-C-103 (Tank C-103) and T-111, and the transfer of documented, developed analytical methods to personnel in the Analytical Chemistry Laboratory (ACL) and 222-S laboratory. This report is intended as an annual report, not a completed work.

Clinical laboratory technician to clinical laboratory scientist articulation and distance learning.

PubMed

Crowley, J R; Laurich, G A; Mobley, R C; Arnette, A H; Shaikh, A H; Martin, S M

1999-01-01

Laboratory workers and educators alike are challenged to support access to education that is current and provides opportunities for career advancement in the work place. The clinical laboratory science (CLS) program at the Medical College of Georgia in Augusta developed a clinical laboratory technician (CLT) to CLS articulation option, expanded it through distance learning, and integrated computer based learning technology into the educational process over a four year period to address technician needs for access to education. Both positive and negative outcomes were realized through these efforts. Twenty-seven students entered the pilot articulation program, graduated, and took a CLS certification examination. Measured in terms of CLS certification, promotions, pay raises, and career advancement, the program described was a success. However, major problems were encountered related to the use of unfamiliar communication technology; administration of the program at distance sites; communication between educational institutions, students, and employers; and competition with CLT programs for internship sites. These problems must be addressed in future efforts to provide a successful distance learning program. Effective methods for meeting educational needs and career ladder expectations of CLTs and their employers are important to the overall quality and appeal of the profession. Educational technology that includes computer-aided instruction, multimedia, and telecommunications can provide powerful tools for education in general and CLT articulation in particular. Careful preparation and vigilant attention to reliable delivery methods as well as students' progress and outcomes is critical for an efficient, economically feasible, and educationally sound program.

Midwest Nuclear Science and Engineering Consortium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dr. Wynn Volkert; Dr. Arvind Kumar; Dr. Bryan Becker

2010-12-08

The objective of the Midwest Nuclear Science and Engineering Consortium (MNSEC) is to enhance the scope, quality and integration of educational and research capabilities of nuclear sciences and engineering (NS/E) programs at partner schools in support of the U.S. nuclear industry (including DOE laboratories). With INIE support, MNSEC had a productive seven years and made impressive progress in achieving these goals. Since the past three years have been no-cost-extension periods, limited -- but notable -- progress has been made in FY10. Existing programs continue to be strengthened and broadened at Consortium partner institutions. The enthusiasm generated by the academic, state,more » federal, and industrial communities for the MNSEC activities is reflected in the significant leveraging that has occurred for our programs.« less

Utilization of a pneumatic tube mixing technique for processing and stabilization of contaminated dredged material.

DOT National Transportation Integrated Search

2016-12-01

The following progress report describes the laboratory activities completed for the development of the experimental field program designed to evaluate sediment amendment using the Pneumatic Flow Tube Mixing Apparatus (PFTM) in NY/NJ Harbor. These act...

Composite Flywheel Development for Energy Storage

DTIC Science & Technology

2005-01-01

Fiber-Composite Flywheel Program: Quarterly Progress Report; UCRL -50033-76-4; Lawrence Livermore National Laboratory: Livermore, CA, 1976. 2...BEACH DAHLGREN VA 22448 1 WATERWAYS EXPERIMENT D SCOTT 3909 HALLS FERRY RD SC C VICKSBURG MS 39180 1 DARPA B WILCOX 3701 N FAIRFAX DR

Spectroscopic Studies of Pre-Biotic Carbon Chemistry

NASA Technical Reports Server (NTRS)

Blake, Geoffrey A.

2002-01-01

As described in the original proposal and in our progress reports, research in the Blake group supported by the Exobiology program seeks to understand the pre-biotic chemistry of carbon along with that of other first- and second-row elements from the earliest stages of star formation through the development of planetary systems. The major tool used is spectroscopy, and the program has observational, laboratory, and theoretical components. The observational and theoretical programs are concerned primarily with a quantitative assessment of the chemical budgets of the biogenic elements in star-forming molecular cloud cores, while the laboratory work is focused on the complex species that characterize the prebiotic chemistry of carbon. We outline below our results over the past two years acquired, in part, with Exobiology support.

Clinical Investigation Program. Annual Progress Report. Volume 1

DTIC Science & Technology

1994-01-20

Suport Labs Resch Chemist 13 0644 GS Salata, KF Allergy Microbiologist 12 0403 CS Billups, L Flow Cytom Microbiologist 12 0403 GS Dobek, AS Inf Disease 5...continued to increase laboratory research support to principal investigators throughout the medical center. The DCI Flow Cytometry Laboratory provided...Kalman PhD. Mitogen-Inducible T Suppressor Cell 12 Assay by Flow Cytometry (12/89) * Reference is to page number(s) in Volume II. 30 PROTOCOL NUMBER

Light-Water-Reactor safety research program. Quarterly progress report, January--March 1977

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

The report summarizes the Argonne National Laboratory work performed during January, February, and March 1977 on water-reactor-safety problems. The following research and development areas are covered: (1) loss-of-coolant accident research: heat transfer and fluid dynamics; (2) transient fuel response and fission-product release program; (3) mechanical properties of zircaloy containing oxygen; and (4) steam-explosion studies.

COED Transactions, Vol. X, No. 6, June 1978. Concentric-Tube Heat Exchanger Analysis and Data Reduction.

ERIC Educational Resources Information Center

Marcovitz, Alan B., Ed.

Four computer programs written in FORTRAN and BASIC develop theoretical predictions and data reduction for a junior-senior level heat exchanger experiment. Programs may be used at the terminal in the laboratory to check progress of the experiment or may be used in the batch mode for interpretation of final information for a formal report. Several…

2014 Water Power Program Peer Review Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

none,

2014-08-18

The Water Power Peer Review Meeting was held February 24-28, 2014 in Arlington, VA. Principle investigators from the Energy Department National Laboratories, academic, and industry representatives presented the progress of their DOE-funded research. This report documents the formal, rigorous evaluation process and findings of nine independent reviewers who examined the technical, scientific, and business results of 96 projects of the Water Power Program, as well as the productivity and management effectiveness of the Water Power Program itself.

Status Report on Efforts to Enhance Instrumentation to Support Advanced Test Reactor Irradiations

DOE Office of Scientific and Technical Information (OSTI.GOV)

J. Rempe; D. Knudson; J. Daw

2014-01-01

The Department of Energy (DOE) designated the Advanced Test Reactor (ATR) as a National Scientific User Facility (NSUF) in April 2007 to support the growth of nuclear science and technology in the United States (US). By attracting new research users - universities, laboratories, and industry - the ATR NSUF facilitates basic and applied nuclear research and development, further advancing the nation's energy security needs. A key component of the ATR NSUF effort at the Idaho National Laboratory (INL) is to design, develop, and deploy new in-pile instrumentation techniques that are capable of providing real-time measurements of key parameters during irradiation.more » To address this need, an assessment of instrumentation available and under-development at other test reactors was completed. Based on this initial review, recommendations were made with respect to what instrumentation is needed at the ATR, and a strategy was developed for obtaining these sensors. In 2009, a report was issued documenting this program’s strategy and initial progress toward accomplishing program objectives. Since 2009, annual reports have been issued to provide updates on the program strategy and the progress made on implementing the strategy. This report provides an update reflecting progress as of January 2014.« less

Fusion Energy Division progress report, 1 January 1990--31 December 1991

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sheffield, J.; Baker, C.C.; Saltmarsh, M.J.

1994-03-01

The Fusion Program of the Oak Ridge National Laboratory (ORNL), a major part of the national fusion program, encompasses nearly all areas of magnetic fusion research. The program is directed toward the development of fusion as an economical and environmentally attractive energy source for the future. The program involves staff from ORNL, Martin Marietta Energy systems, Inc., private industry, the academic community, and other fusion laboratories, in the US and abroad. Achievements resulting from this collaboration are documented in this report, which is issued as the progress report of the ORNL Fusion Energy Division; it also contains information from componentsmore » for the Fusion Program that are external to the division (about 15% of the program effort). The areas addressed by the Fusion Program include the following: experimental and theoretical research on magnetic confinement concepts; engineering and physics of existing and planned devices, including remote handling; development and testing of diagnostic tools and techniques in support of experiments; assembly and distribution to the fusion community of databases on atomic physics and radiation effects; development and testing of technologies for heating and fueling fusion plasmas; development and testing of superconducting magnets for containing fusion plasmas; development and testing of materials for fusion devices; and exploration of opportunities to apply the unique skills, technology, and techniques developed in the course of this work to other areas (about 15% of the Division`s activities). Highlights from program activities during 1990 and 1991 are presented.« less

Pacific Northwest Laboratory annual report for 1993 to the DOE Office of Energy Research. Part 1: Biomedical Sciences

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lumetta, C.C.; Park, J.F.

1994-03-01

This report summarizes FY 1993 progress in biological and general life sciences research programs conducted for the Department of Energy`s Office of Health and Environmental REsearch (OHER) at Pacific Northwest Laboratory (PNL). This research provides knowledge of fundamental principles necessary to identify, understand, and anticipate the long-term health consequences of exposure to energy-related radiation and chemicals. The Biological Research section contains reports of studies using laboratory animals, in vitro cell systems, and molecular biological systems. This research includes studies of the impact of radiation, radionuclides, and chemicals on biological responses at all levels of biological organization. The General Life Sciencesmore » Research section reports research conducted for the OHER human genome program.« less

Key results of battery performance and life tests at Argonne National Laboratory

NASA Astrophysics Data System (ADS)

Deluca, W. H.; Gillie, K. R.; Kulaga, J. E.; Smaga, J. A.; Tummillo, A. F.; Webster, C. E.

1991-12-01

Advanced battery technology evaluations are performed under simulated electric vehicle operating conditions at Argonne National Laboratory's & Diagnostic Laboratory (ADL). The ADL provide a common basis for both performance characterization and life evaluation with unbiased application of tests and analyses. This paper summarizes the performance characterizations and life evaluations conducted in 1991 on twelve single cells and eight 3- to 360-cell modules that encompass six battery technologies (Na/S, Li/MS, Ni/MH, Zn/Br, Ni/Fe, and Pb-Acid). These evaluations were performed for the Department of Energy, Office of Transportation Technologies, Electric and Hybrid Propulsion Division. The results measure progress in battery R & D programs, compare battery technologies, and provide basic data for modeling and continuing R & D to battery users, developers, and program managers.

Transportation Research and Analysis Computing Center (TRACC) Year 6 Quarter 4 Progress Report

DOT National Transportation Integrated Search

2013-03-01

Argonne National Laboratory initiated a FY2006-FY2009 multi-year program with the US Department of Transportation (USDOT) on October 1, 2006, to establish the Transportation Research and Analysis Computing Center (TRACC). As part of the TRACC project...

1982 Naval Research Laboratory Review,

DTIC Science & Technology

1983-01-01

is a principal concern of NRL manage - small, specialized laboratories. ment. The Review also serves as a resource docu- NIRL’s position is unique in...us an oppor- it was founded-people-programs-progress- tunity to assess and report our contribution to the innovation ; and that this combination will...0 vi WtL 2004020/824 *%2 J M-A b. t L ~~ SE -A COORDINATION AND DUAL Leal RSPONSIILITY MANAGEMENT DCNM NNANPRDC WOCDTNS7RDC NWC NAVSA ASK RAM

High-temperature gas-cooled reactor technology development program. Annual progress report for period ending December 31, 1982

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kasten, P.R.; Rittenhouse, P.L.; Bartine, D.E.

1983-06-01

During 1982 the High-Temperature Gas-Cooled Reactor (HTGR) Technology Program at Oak Ridge National Laboratory (ORNL) continued to develop experimental data required for the design and licensing of cogeneration HTGRs. The program involves fuels and materials development (including metals, graphite, ceramic, and concrete materials), HTGR chemistry studies, structural component development and testing, reactor physics and shielding studies, performance testing of the reactor core support structure, and HTGR application and evaluation studies.

A position paper of the EFLM Committee on Education and Training and Working Group on Distance Education Programmes/E-Learning: developing an e-learning platform for the education of stakeholders in laboratory medicine.

PubMed

Gruson, Damien; Faure, Gilbert; Gouget, Bernard; Haliassos, Alexandre; Kisikuchin, Darya; Reguengo, Henrique; Topic, Elizabeta; Blaton, Victor

2013-04-01

The progress of information and communication technologies has strongly influenced changes in healthcare and laboratory medicine. E-learning, the learning or teaching through electronic means, contributes to the effective knowledge translation in medicine and healthcare, which is an essential element of a modern healthcare system and for the improvement of patient care. E-learning also represents a great vector for the transfer knowledge into laboratory practice, stimulate multidisciplinary interactions, enhance continuing professional development and promote laboratory medicine. The European Federation of Laboratory Medicine (EFLM) has initiated a distance learning program and the development of a collaborative network for e-learning. The EFLM dedicated working group encourages the organization of distance education programs and e-learning courses as well as critically evaluate information from courses, lectures and documents including electronic learning tools. The objectives of the present paper are to provide some specifications for distance learning and be compatible with laboratory medicine practices.

Progress in Harmonizing Tiered HIV Laboratory Systems: Challenges and Opportunities in 8 African Countries.

PubMed

Williams, Jason; Umaru, Farouk; Edgil, Dianna; Kuritsky, Joel

2016-09-28

In 2014, the Joint United Nations Programme on HIV/AIDS released its 90-90-90 targets, which make laboratory diagnostics a cornerstone for measuring efforts toward the epidemic control of HIV. A data-driven laboratory harmonization and standardization approach is one way to create efficiencies and ensure optimal laboratory procurements. Following the 2008 "Maputo Declaration on Strengthening of Laboratory Systems"-a call for government leadership in harmonizing tiered laboratory networks and standardizing testing services-several national ministries of health requested that the United States Government and in-country partners help implement the recommendations by facilitating laboratory harmonization and standardization workshops, with a primary focus on improving HIV laboratory service delivery. Between 2007 and 2015, harmonization and standardization workshops were held in 8 African countries. This article reviews progress in the harmonization of laboratory systems in these 8 countries. We examined agreed-upon instrument lists established at the workshops and compared them against instrument data from laboratory quantification exercises over time. We used this measure as an indicator of adherence to national procurement policies. We found high levels of diversity across laboratories' diagnostic instruments, equipment, and services. This diversity contributes to different levels of compliance with expected service delivery standards. We believe the following challenges to be the most important to address: (1) lack of adherence to procurement policies, (2) absence or limited influence of a coordinating body to fully implement harmonization proposals, and (3) misalignment of laboratory policies with minimum packages of care and with national HIV care and treatment guidelines. Overall, the effort to implement the recommendations from the Maputo Declaration has had mixed success and is a work in progress. Program managers should continue efforts to advance the principles outlined in the Maputo Declaration. Quantification exercises are an important method of identifying instrument diversity, and provide an opportunity to measure efforts toward standardization. © Williams et al.

Spectroscopic Studies of Pre-Biotic Carbon Chemistry

NASA Technical Reports Server (NTRS)

Blake, Geoffrey A.

2003-01-01

As described in the original proposal and in our progress reports, research in the Blake group supported by the Exobiology program seeks to understand the pre-biotic chemistry of carbon along with that of other first- and second-row elements from the earliest stages of star formation through the development of planetary systems. The major tool used is spectroscopy, and the program has observational, laboratory, and theoretical components. The observational and theoretical programs are concerned primarily with a quantitative assessment of the chemical budgets of the biogenic elements in the circumstellar environment of forming stars and planetary systems, while the laboratory work is focused on the complex species that characterize the pre-biotic chemistry of carbon. We outline below our results over the past year acquired, in part, with Exobiology support.

Progress in Harmonizing Tiered HIV Laboratory Systems: Challenges and Opportunities in 8 African Countries

PubMed Central

Williams, Jason; Umaru, Farouk; Edgil, Dianna; Kuritsky, Joel

2016-01-01

ABSTRACT In 2014, the Joint United Nations Programme on HIV/AIDS released its 90-90-90 targets, which make laboratory diagnostics a cornerstone for measuring efforts toward the epidemic control of HIV. A data-driven laboratory harmonization and standardization approach is one way to create efficiencies and ensure optimal laboratory procurements. Following the 2008 “Maputo Declaration on Strengthening of Laboratory Systems”—a call for government leadership in harmonizing tiered laboratory networks and standardizing testing services—several national ministries of health requested that the United States Government and in-country partners help implement the recommendations by facilitating laboratory harmonization and standardization workshops, with a primary focus on improving HIV laboratory service delivery. Between 2007 and 2015, harmonization and standardization workshops were held in 8 African countries. This article reviews progress in the harmonization of laboratory systems in these 8 countries. We examined agreed-upon instrument lists established at the workshops and compared them against instrument data from laboratory quantification exercises over time. We used this measure as an indicator of adherence to national procurement policies. We found high levels of diversity across laboratories’ diagnostic instruments, equipment, and services. This diversity contributes to different levels of compliance with expected service delivery standards. We believe the following challenges to be the most important to address: (1) lack of adherence to procurement policies, (2) absence or limited influence of a coordinating body to fully implement harmonization proposals, and (3) misalignment of laboratory policies with minimum packages of care and with national HIV care and treatment guidelines. Overall, the effort to implement the recommendations from the Maputo Declaration has had mixed success and is a work in progress. Program managers should continue efforts to advance the principles outlined in the Maputo Declaration. Quantification exercises are an important method of identifying instrument diversity, and provide an opportunity to measure efforts toward standardization. PMID:27688718

Teaching laboratory neuroscience at bowdoin: the laboratory instructor perspective.

PubMed

Hauptman, Stephen; Curtis, Nancy

2009-01-01

Bowdoin College is a small liberal arts college that offers a comprehensive Neuroscience major. The laboratory experience is an integral part of the major, and many students progress through three stages. A core course offers a survey of concepts and techniques. Four upper-level courses function to give students more intensive laboratory research experience in neurophysiology, molecular neurobiology, social behavior, and learning and memory. Finally, many majors choose to work in the individual research labs of the Neuroscience faculty. We, as laboratory instructors, are vital to the process, and are actively involved in all aspects of the lab-based courses. We provide student instruction in state of the art techniques in neuroscience research. By sharing laboratory teaching responsibilities with course professors, we help to prepare students for careers in laboratory neuroscience and also support and facilitate faculty research programs.

The Telecommunications and Data Acquisition Report

NASA Technical Reports Server (NTRS)

Posner, Edward C. (Editor)

1992-01-01

Archival reports on developments in programs managed by the Jet Propulsion Laboratory's (JPL's) Office of Telecommunications and Data Acquisition (TDA) are published in the TDA Progress Report. In the search for extraterrestrial intelligence (SETI), the TDA Progress Report reports on implementation and operations for searching the microwave spectrum. In solar system radar, it reports on the uses of the Goldstone Solar System Radar for scientific exploration of the planets, their rings and satellites, asteroids, and comets. In radio astronomy, the areas of support include spectroscopy, very long baseline interferometry, and astrometry. These three programs are performed for NASA's Office of Space Science and Applications (OSSA), with the Office of Space Operations funding DSN operational support.

Biology, Medicine, and the Bill of Rights. Special Report.

ERIC Educational Resources Information Center

Congress of the U.S., Washington, DC. Office of Technology Assessment.

The rapid progress in the biological sciences has resulted in many social, ethical, and legal issues. In medical practice, public health programs, research laboratories, law enforcement, insurance, the patenting process, agriculture, genetic counseling, and other fields, legal controversies and public policy debates have developed. Some of these…

NATIONAL HEALTH & ENVIRONMENTAL EFFECTS RESEARCH LABORATORY BEGINS IMPLEMENTATION OF AN ELECTRONIC SCIENTIFIC DATA MANAGEMENT SYSTEM

EPA Science Inventory

Data and records management have changed greatly as a result of progress in computer technology, but many organizations, including the US EPA's National Records Management Program (NRMP) and the U.S. National Archives and Records Administration (NARA), still struggle to escape th...

1989 Environmental monitoring report, Sandia National Laboratories, Albuquerque, New Mexico

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hwang, S.; Chavez, G.; Phelan, J.

1990-05-01

This 1989 report contains monitoring data from routine radiological and nonradiological environmental surveillance activities. Summaries of significant environmental compliance programs in progress such as National Environmental Policy Act documentation, environmental permits, environmental restoration, and various waste management programs for Sandia National Laboratories in Albuquerque (SNL, Albuquerque) are included. The maximum offsite dose impact was calculated to be 8.8 {times} 10{sup {minus}4} mrem. The total Albuquerque population received a collective dose of 0.097 person-rem during 1989 from SNL, Albuquerque, operations. As in the previous year, SNL, Albuquerque, operations in 1989 had no adverse impact on the general public or on themore » environment. 46 refs., 20 figs., 31 tabs.« less

Laboratory-directed research and development: FY 1996 progress report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vigil, J.; Prono, J.

1997-05-01

This report summarizes the FY 1996 goals and accomplishments of Laboratory-Directed Research and Development (LDRD) projects. It gives an overview of the LDRD program, summarizes work done on individual research projects, and provides an index to the projects` principal investigators. Projects are grouped by their LDRD component: Individual Projects, Competency Development, and Program Development. Within each component, they are further divided into nine technical disciplines: (1) materials science, (2) engineering and base technologies, (3) plasmas, fluids, and particle beams, (4) chemistry, (5) mathematics and computational sciences, (6) atomic and molecular physics, (7) geoscience, space science, and astrophysics, (8) nuclear andmore » particle physics, and (9) biosciences.« less

Development of an All Solid State 6 kHz Pulse Generator for Driving Free Electron Laser Amplifiers

DTIC Science & Technology

1990-07-16

programs. 1-6 SCIENCE RESEARCH LABORATORY In these efforts, Science Research Laboratory is exploiting recent progress in Silicon Con- trolled Rectifier...electrons in silicon as opposed to the low pressure gas in the thyratron. In addition these all-solid-state SCR-switched drivers can be engineered to...nsec PFN 2-5 C Li Figure 2.3: Electrical schematic and cross-sectional view of SNOMAD-11 SCR corn - mutated pulse compression driver. 2-5 SCIENCE

Fossil energy program

NASA Astrophysics Data System (ADS)

McNeese, L. E.

1981-12-01

The progress made during the period from July 1 through September 30 for the Oak Ridge National Laboratory research and development projects in support of the increased utilization of coal and other fossil fuels as sources of clean energy is reported. The following topics are discussed: coal conversion development, chemical research and development, materials technology, fossil energy materials program, liquefaction projects, component development, process analysis, environmental control technology, atmospheric fluidized bed combustion, underground coal gasification, coal preparation and waste utilization.

MIT Laboratory for Computer Science Progress Report 20 - July 1982 - Jun 1983,

DTIC Science & Technology

1984-07-01

system by the Programming Technology Group. Research in the second and largest area entitled Machines, Languages , and Systems, strives to discover and...utilization and cost effectiveness . For example, the Programming Methodology Group and the Real Time Systems Group are developing languages and...100 Megabits per second when implemented with the 1.2[im. n- well cMOS process. 3. LANGUAGES 3.1. Demand Driven Evaluation In his engineer’s thesis

LLE 2010 Annual Report October 2009 - September 2010

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2011-01-01

The fiscal year ending September 2010 (FY10) concluded the third year of the third five-year renewal of Cooperative Agreement DE-FC52-08NA28302 with the U.S. Department of Energy (DOE). This annual report summarizes progress in inertial fusion research at the Laboratory for Laser Energetics (LLE) during the past fiscal year including work on the National Ignition Campaign (NIC). It also reports on LLE's progress on laboratory basic science research; laser, optical materials, and advanced technology development; operation of OMEGA and OMEGA EP for the NIC and high-energy density (HED) campaigns, the National Laser Users Facility (NLUF), and for other external users; andmore » programs focusing on the education of high school, undergraduate, and graduate students during the year.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

ENGEL-COX,J.; ZIMMERMAN,E.; LEE,R.

Throughout the scientific community, Brookhaven National Laboratory (BNL) is renowned for its leading-edge research in physics, medicine, chemistry, biology, materials, and the environment. BNL is committed to supporting its world-class scientific research with an internationally recognized environmental protection program. The 1999 Site Environmental Report (SER) summarizes the status of the Laboratory's environmental programs and performance, including the steady progress towards cleaning up the site and fully integrating environmental stewardship into all facets of the Laboratory's mission. BNL is located on 5,265 acres of pine barrens in Suffolk County in the center of Long Island, New York. The Laboratory is situatedmore » above a sole source aquifer at the headwaters of the Peconic River; therefore, protecting ground and surface water quality is a special concern. Approximately 3,600 acres of the site are undeveloped and serve as habitat for a wide variety of animals and plants, including one New York State endangered species, the tiger salamander, and two New York State threatened species, the banded sunfish and the stiff goldenrod. Monitoring, preserving, and restoring these ecological resources is a high priority for the Laboratory.« less

Electric and Hybrid Vehicles Program. Sixteenth annual report to Congress for fiscal year 1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-08-01

This report describes the progress achieved in developing electric and hybrid vehicle technologies, beginning with highlights of recent accomplishments in FY 1992. Detailed descriptions are provided of program activities during FY 1992 in the areas of battery, fuel cell, and propulsion system development, and testing and evaluation of new technology in fleet site operations and in laboratories. This Annual Report also contains a status report on incentives and use of foreign components, as well as a list of publications resulting from the DOE program.

Space debris measurement program at Phillips Laboratory

NASA Technical Reports Server (NTRS)

Dao, Phan D.; Mcnutt, Ross T.

1992-01-01

Ground-based optical sensing was identified as a technique for measuring space debris complementary to radar in the critical debris size range of 1 to 10 cm. The Phillips Laboratory is building a staring optical sensor for space debris measurement and considering search and track optical measurement at additional sites. The staring sensor is implemented in collaboration with Wright Laboratory using the 2.5 m telescope at Wright Patterson AFB, Dayton, Ohio. The search and track sensor is designed to detect and track orbital debris in tasked orbits. A progress report and a discussion of sensor performance and search and track strategies will be given.

Legal aspects associated with dismissal from clinical laboratory education programs.

PubMed

Legrys, V A; Beck, S J; Laudicina, R J

1995-01-01

To review academic dismissals, students' rights in dismissal cases, and several key cases involving academic and disciplinary dismissals. Recent academic literature and legal precedents. Not applicable. Not applicable. Students involved in dismissals are protected under the principles of constitutional law and/or contract law, depending on whether the institution is public or private. The basis for dismissal from educational programs is either academic or disciplinary in nature. In academic dismissals, a student has failed to meet either the cognitive or the noncognitive academic standards of the program. In disciplinary dismissals, a student has violated the institutional rules governing conduct. Policies that affect progress in the program and the dismissal process should be published and distributed to students, as well as reviewed for consistency with institutional policies. The amount of documentation needed in the defense of a dismissal decision has not been specified, but, in general, more is better. Procedures are suggested as a guide to dismissals in clinical laboratory programs.

Laboratory quality improvement in Tanzania.

PubMed

Andiric, Linda R; Massambu, Charles G

2015-04-01

The article describes the implementation and improvement in the first groups of medical laboratories in Tanzania selected to participate in the training program on Strengthening Laboratory Management Toward Accreditation (SLMTA). As in many other African nations, the selected improvement plan consisted of formalized hands-on training (SLMTA) that teaches the tasks and skills of laboratory management and provides the tools for implementation of best laboratory practice. Implementation of the improvements learned during training was verified before and after SLMTA with the World Health Organization African Region Stepwise Laboratory Improvement Process Towards Accreditation checklist. During a 4-year period, the selected laboratories described in this article demonstrated improvement with a range of 2% to 203% (cohort I) and 12% to 243% (cohort II) over baseline scores. The article describes the progress made in Tanzania's first cohorts, the obstacles encountered, and the lessons learned during the pilot and subsequent implementations. Copyright© by the American Society for Clinical Pathology.

Assessment of Proficiency and Competency in Laboratory Animal Biomethodologies

PubMed Central

Clifford, Paula; Melfi, Natasha; Bogdanske, John; Johnson, Elizabeth J; Kehler, James; Baran, Szczepan W

2013-01-01

Personnel working with laboratory animals are required by laws and guidelines to be trained and qualified to perform biomethodologic procedures. The assessment of competency and proficiency is a vital component of a laboratory animal training program, because this process confirms that the trainees have met the learning objectives for a particular procedure. The approach toward qualification assessment differs between organizations because laws and guidelines do not outline how the assessment should be performed or which methods and tools should be used. Assessment of clinical and surgical medicine has received considerable attention over the last few decades and has progressed from simple subjective methods to well-defined and objective methods of assessing competency. Although biomethodology competency and proficiency assessment is discussed in the literature, a standard and objective assessment method has not yet been developed. The development and implementation of an objective and standardized biomethodologic assessment program can serve as a tool to improve standards, ensure consistent training, and decrease research variables yet ensure animal welfare. Here we review the definition and goals of training and assessment, review assessment methods, and propose a method to develop a standard and objective assessment program for the laboratory animal science field, particularly training departments and IACUC. PMID:24351758

Dental Charting. Learning Activities, Unit Tests, Progress Chart, and Work Sheet.

ERIC Educational Resources Information Center

Texas Univ., Austin. Center for Occupational Curriculum Development.

These materials are part of a series dealing with skills and information needed by students in dental assisting. The individualized student materials are suitable for classroom, laboratory, or cooperative training programs. These student materials, designed to be used with the Dental Charting Student Manual, consist of learning activities, unit…

Physics division progress report for period ending September 30 1991

DOE Office of Scientific and Technical Information (OSTI.GOV)

Livingston, A.B.

1992-03-01

This report discusses research being conducted at Oak Ridge National Laboratory in physics. The areas covered are: Holifield Heavy Ion Research Facility; low/medium energy nuclear physics; high energy experimental physics; the Unisor program; experimental atomic physics; laser and electro-optics lab; theoretical physics; compilations and evaluations; and radioactive ion beam development. (LSP)

Summary of U.S. research on wood transportation structures

Treesearch

M. A. Ritter; R. C. Moody; S. R. Duwadi

1996-01-01

An extensive U.S. research program to further develop wood utilization in transportation structures is currently in progress as a joint effort of the USDA Forest Service, Forest Products Laboratory, and the U.S. Department of Transportation, Federal Highway Administration. This research is funded primarily by U.S. legislation and involves cooperative research with...

INEL BNCT Research Program Annual Report 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Venhuizen, J.R.

1994-08-01

This report is a summary of the progress and research produced for the Idaho National Engineering Laboratory Boron Neutron Capture Therapy Research Program for calendar year 1993. Contributions from all the principal investigators are included, covering chemistry (pituitary tumor studies, boron drug development including liposomes, lipoproteins, and carboranylalanine derivatives), pharmacology (murine screenings, toxicity testing, boron drug analysis), physics (radiation dosimetry software, neutron beam and filter design, neutron beam measurement dosimetry), and radiation biology (tissue and efficacy studies of small and large animal models). Information on the potential toxicity of borocaptate sodium and boronophenylalanine is presented. Results of 21 spontaneous-tumor-bearing dogsmore » that have been treated with boron neutron capture therapy at the Brookhaven National Laboratory are updated. Boron-containing drug purity verification is discussed in some detail. Advances in magnetic resonance imaging of boron in vivo are discussed. Several boron-carrying drugs exhibiting good tumor uptake are described. Significant progress in the potential of treating pituitary tumors is presented. Measurement of the epithermal-neutron flux of the Petten (The Netherlands) High Flux Reactor beam (HFB11B), and comparison to predictions are shown.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sjoreen, Terrence P

The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2A, 'Laboratory Directed Research and Development' (January 8, 2001), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report describes all ORNL LDRD research activities supported during FY 2005 and includes final reports for completed projects and shorter progress reports for projects thatmore » were active, but not completed, during this period. The FY 2005 ORNL LDRD Self-Assessment (ORNL/PPA-2006/2) provides financial data about the FY 2005 projects and an internal evaluation of the program's management process. ORNL is a DOE multiprogram science, technology, and energy laboratory with distinctive capabilities in materials science and engineering, neutron science and technology, energy production and end-use technologies, biological and environmental science, and scientific computing. With these capabilities ORNL conducts basic and applied research and development (R&D) to support DOE's overarching national security mission, which encompasses science, energy resources, environmental quality, and national nuclear security. As a national resource, the Laboratory also applies its capabilities and skills to the specific needs of other federal agencies and customers through the DOE Work For Others (WFO) program. Information about the Laboratory and its programs is available on the Internet at . LDRD is a relatively small but vital DOE program that allows ORNL, as well as other multiprogram DOE laboratories, to select a limited number of R&D projects for the purpose of: (1) maintaining the scientific and technical vitality of the Laboratory; (2) enhancing the Laboratory's ability to address future DOE missions; (3) fostering creativity and stimulating exploration of forefront science and technology; (4) serving as a proving ground for new research; and (5) supporting high-risk, potentially high-value R&D. Through LDRD the Laboratory is able to improve its distinctive capabilities and enhance its ability to conduct cutting-edge R&D for its DOE and WFO sponsors. To meet the LDRD objectives and fulfill the particular needs of the Laboratory, ORNL has established a program with two components: the Director's R&D Fund and the Seed Money Fund. As outlined in Table 1, these two funds are complementary. The Director's R&D Fund develops new capabilities in support of the Laboratory initiatives, while the Seed Money Fund is open to all innovative ideas that have the potential for enhancing the Laboratory's core scientific and technical competencies. Provision for multiple routes of access to ORNL LDRD funds maximizes the likelihood that novel and seminal ideas with scientific and technological merit will be recognized and supported.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sjoreen, Terrence P

The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2A, 'Laboratory Directed Research and Development' (January 8, 2001), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report describes all ORNL LDRD research activities supported during FY 2004 and includes final reports for completed projects and shorter progress reports for projects thatmore » were active, but not completed, during this period. The FY 2004 ORNL LDRD Self-Assessment (ORNL/PPA-2005/2) provides financial data about the FY 2004 projects and an internal evaluation of the program's management process. ORNL is a DOE multiprogram science, technology, and energy laboratory with distinctive capabilities in materials science and engineering, neutron science and technology, energy production and end-use technologies, biological and environmental science, and scientific computing. With these capabilities ORNL conducts basic and applied research and development (R&D) to support DOE's overarching national security mission, which encompasses science, energy resources, environmental quality, and national nuclear security. As a national resource, the Laboratory also applies its capabilities and skills to the specific needs of other federal agencies and customers through the DOE Work For Others (WFO) program. Information about the Laboratory and its programs is available on the Internet at . LDRD is a relatively small but vital DOE program that allows ORNL, as well as other multiprogram DOE laboratories, to select a limited number of R&D projects for the purpose of: (1) maintaining the scientific and technical vitality of the Laboratory; (2) enhancing the Laboratory's ability to address future DOE missions; (3) fostering creativity and stimulating exploration of forefront science and technology; (4) serving as a proving ground for new research; and (5) supporting high-risk, potentially high-value R&D. Through LDRD the Laboratory is able to improve its distinctive capabilities and enhance its ability to conduct cutting-edge R&D for its DOE and WFO sponsors. To meet the LDRD objectives and fulfill the particular needs of the Laboratory, ORNL has established a program with two components: the Director's R&D Fund and the Seed Money Fund. As outlined in Table 1, these two funds are complementary. The Director's R&D Fund develops new capabilities in support of the Laboratory initiatives, while the Seed Money Fund is open to all innovative ideas that have the potential for enhancing the Laboratory's core scientific and technical competencies. Provision for multiple routes of access to ORNL LDRD funds maximizes the likelihood that novel and seminal ideas with scientific and technological merit will be recognized and supported.« less

1991 Environmental monitoring report Sandia National Laboratories, Albuquerque, New Mexico

DOE Office of Scientific and Technical Information (OSTI.GOV)

Culp, T.; Cox, W.; Hwang, S.

1992-11-01

This 1991 report contains monitoring data from routine radiological and nonradiological environmental surveillance activities. Summaries of significant environmental compliance programs in progress such as National Environmental Policy Act (NEPA) documentation, environmental permits, environmental restoration (ER), and various waste management programs for Sandia National Laboratories in Albuquerque (SNL, Albuquerque) are included. The maximum offsite dose impact was calculated to be 1.3 {times} 10{sup {minus}3} mrem. The total population within a 50-mile radius of SNL, Albuquerque, received a collective dose of 0.53 person-rem during 1991 from SNL, Albuquerque, operations. As in the previous year, the 1991 operations at SNL, Albuquerque, had nomore » discernible impact on the general public or on the environment.« less

Comprehensive computerized diabetes registry. Serving the Cree of Eeyou Istchee (eastern James Bay).

PubMed Central

Dannenbaum, D.; Verronneau, M.; Torrie, J.; Smeja, H.; Robinson, E.; Dumont, C.; Kovitch, I.; Webster, T.

1999-01-01

PROBLEM BEING ADDRESSED: Diabetes is rapidly evolving as a major health concern in the Cree population of eastern James Bay (Eeyou Istchee). The Cree Board of Health and Social Services of James Bay (CBHSSJB) diabetes registry was the initial phase in the development of a comprehensive program for diabetes in this region. OBJECTIVE OF PROGRAM: The CBHSSJB diabetes registry was developed to provide a framework to track the prevalence of diabetes and the progression of diabetic complications. The database will also identify patients not receiving appropriate clinical and laboratory screening for diabetic complications, and will provide standardized clinical flow sheets for routine patient management. MAIN COMPONENTS OF PROGRAM: The CBHSSJB diabetes registry uses a system of paper registration forms and clinical flow sheets kept in the nine community clinics. Information from these sheets is entered into a computer database annually. The flow sheets serve as a guideline for appropriate management of patients with diabetes, and provide a one-page summary of relevant clinical and laboratory information. CONCLUSIONS: A diabetes registry is vital to follow the progression of diabetes and diabetic complications in the region served by the CBHSSJB. The registry system incorporates both a means for regional epidemiologic monitoring of diabetes mellitus and clinical tools for managing patients with the disease. PMID:10065310

Biology Division progress report, October 1, 1993--September 30, 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-10-01

This Progress Report summarizes the research endeavors of the Biology Division of the Oak Ridge National Laboratory during the period October 1, 1993, through September 30, 1995. The report is structured to provide descriptions of current activities and accomplishments in each of the Division`s major organizational units. Lists of information to convey the entire scope of the Division`s activities are compiled at the end of the report. Attention is focused on the following research activities: molecular, cellular, and cancer biology; mammalian genetics and development; genome mapping program; and educational activities.

The Role of Research in Viral Disease Eradication and Elimination Programs: Lessons for Malaria Eradication

PubMed Central

Breman, Joel G.; de Quadros, Ciro A.; Dowdle, Walter R.; Foege, William H.; Henderson, Donald A.; John, T. Jacob; Levine, Myron M.

2011-01-01

By examining the role research has played in eradication or regional elimination initiatives for three viral diseases—smallpox, poliomyelitis, and measles—we derive nine cross-cutting lessons applicable to malaria eradication. In these initiatives, some types of research commenced as the programs began and proceeded in parallel. Basic laboratory, clinical, and field research all contributed notably to progress made in the viral programs. For each program, vaccine was the lynchpin intervention, but as the programs progressed, research was required to improve vaccine formulations, delivery methods, and immunization schedules. Surveillance was fundamental to all three programs, whilst polio eradication also required improved diagnostic methods to identify asymptomatic infections. Molecular characterization of pathogen isolates strengthened surveillance and allowed insights into the geographic source of infections and their spread. Anthropologic, sociologic, and behavioural research were needed to address cultural and religious beliefs to expand community acceptance. The last phases of elimination and eradication became increasingly difficult, as a nil incidence was approached. Any eradication initiative for malaria must incorporate flexible research agendas that can adapt to changing epidemiologic contingencies and allow planning for posteradication scenarios. PMID:21311582

Materials R&D-student internships

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thompson, R.B.; Jiles, D.C.; Chumbley, L.S.

1995-05-01

This program has as an objective the conduct of programmatic research for the Advanced Industrial Concepts Materials Program while training minority graduate students in the process. Well-known demographics indicate that minorities will constitute an increasing fraction of our future work force. Consequently, efforts have been initiated to increase the fraction of minorities and women who choose technical career paths. Included are a wide ranging set of programs beginning with pre-school education, progressing through efforts to retain students in technical paths in grades K-12 and undergraduate education, and ending with encouraging graduate education. The Materials R & D - Student Internshipsmore » is a unique approach in the latter category. Here, we have focused on a particular area of applied materials research, the Advanced Industrial Concepts Materials Program. Our goal, then, is to educate minority graduate students in the context of this program. The Ames Laboratory was selected as a site for this pilot project since it is a DOE national laboratory, located on the campus of a major research university, which includes in its research interests programs with a strong technological flavor.« less

INEEL BNCT research program. Annual report, January 1, 1996--December 31, 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

Venhuizen, J.R.

1997-04-01

This report is a summary of the progress and research produced for the Idaho National Engineering and Environmental Laboratory (INEEL) Boron Neutron Capture Therapy (BNCT) Research Program for calendar year 1996. Contributions from the individual investigators about their projects are included, specifically, physics: treatment planning software, real-time neutron beam measurement dosimetry, measurement of the Finnish research reactor epithermal neutron spectrum, BNCT accelerator technology; and chemistry: analysis of biological samples and preparation of {sup 10}B enriched decaborane.

Helping early career research scientists ascend the professional ladder.

PubMed

King, Laina

2013-08-01

The Keystone Symposia Early Career Investigator Travel Award initiative is a unique successful research mentoring program tailored for 'end of the pipeline' life and biomedical scientists from academia and industry. Using targeted educational, mentoring, and networking activities, the program benefits early career scientists in solving a specific laboratory-based research question that is limiting their evolving research and could increase their ability to obtain new grants and improve their career progression. Copyright © 2013 Elsevier Ltd. All rights reserved.

Building America Systems Integration Research Annual Report. FY 2012

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gestwick, Michael

2013-05-01

This Building America FY2012 Annual Report includes an overview of the Building America Program activities and the work completed by the National Renewable Energy Laboratory and the Building America industry consortia (the Building America teams). The annual report summarizes major technical accomplishments and progress towards U.S. Department of Energy Building Technologies Program's multi-year goal of developing the systems innovations that enable risk-free, cost effective, reliable and durable efficiency solutions that reduce energy use by 30%-50% in both new and existing homes.

Postdoctoral and Senior Postdoctoral Resident Research Associateship Program and Research Management Associateship Program for the National Aeronautics and Space Administration

NASA Technical Reports Server (NTRS)

1986-01-01

Information on the status of all Resident Research Associated and Research Management Associates is provided. All Associated whose tenure continued as of June 1, 1985 are listed alphabetically by laboratory. Also included are their countries of citizenship and dates of tenure. The status of reporting obligations are summarized. A list of progress reports received during this reporting period is also provided. All Associates who terminated during the reporting period are listed.

Institutional research and development, FY 1988

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1988-01-01

The Laboratory's Institutional Research and Development (IR and D) Program was established in 1984 to foster exploratory work to advance science and technology, disciplinary research to develop innovative solutions to support our national defense and energy missions. In FY 1988, the IR and D Program was funded by a 2% assessment on the Laboratory's operating budget. Our policy is to use these funds for researching innovative ideas in LLNL's areas of expertise and for developing new areas of expertise that we perceive to be in the national interest. The technical and scientific accomplishments of each project and of each institutemore » funded this year are presented in this report. The projects were selected because they are expected to advance research in important areas that are too basic or too time consuming to be funded by the developmental programs or because they are somewhat risky projects that have the promise of high payoff. We are continually reappraising the IR and D Program. In particular, we seek new candidates for the Director's Initiatives, and we constantly reassess the work in progress. Each year, we make adjustments to further the Laboratory's policy of using the IR and D Program to fund innovative ideas with high potential for enhancing programmatic activities of national importance.« less

Rapid Ascent From Zero Quality to International Organization for Standardization Accreditation: A Case Study of Hai Duong Preventive Medicine Center in Vietnam, 2012-2013.

PubMed

Duong, Cuong Ngoc; Bond, Kyle B; Carvalho, Humberto; Thi Thu, Hien Bui; Nguyen, Thuong; Rush, Thomas

2017-04-01

In 2012, the Vietnam Ministry of Health sought to improve the quality of health laboratories by introducing international quality standards. Strengthening Laboratory Management Toward Accreditation (SLMTA), a year-long, structured, quality improvement curriculum (including projects and mentorship) was piloted in 12 laboratories. Progress was measured using a standardized audit tool (Stepwise Laboratory Quality Improvement Process Towards Accreditation). All 12 pilot laboratories (a mix of hospital and public health) demonstrated improvement; median scores rose from 44% to 78% compliance. The public health laboratory in Hai Duong Province entered the program with the lowest score of the group (28%) yet concluded with the highest score (86%). Five months after the completion of the program, without any additional external support, they were accredited. Laboratory management/staff describe factors key to their success: support from the facility senior management, how-to guidance provided by SLMTA, support from the site mentor, and strong commitment of laboratory staff. Hai Duong preventive medical center is one of only a handful of laboratories to reach accreditation after participation in SLMTA and the only laboratory to do so without additional support. Due to the success seen in Hai Duong and other pilot laboratories, Vietnam has expanded the use of SLMTA. American Society for Clinical Pathology, 2017. This work is written by US Government employees and is in the public domain in the US.

Solar photovoltaic research and development program of the Air Force Aero Propulsion Laboratory. [silicon solar cell applicable to satellite power systems

NASA Technical Reports Server (NTRS)

Wise, J.

1979-01-01

Progress is reported in the following areas: laser weapon effects, solar silicon solar cell concepts, and high voltage hardened, high power system technology. Emphasis is placed on solar cells with increased energy conversion efficiency and radiation resistance characteristics for application to satellite power systems.

Comparative Effects of Different Balance-Training-Progression Styles on Postural Control and Ankle Force Production: A Randomized Controlled Trial.

PubMed

Cuğ, Mutlu; Duncan, Ashley; Wikstrom, Erik

2016-02-01

Despite the effectiveness of balance training, the exact parameters needed to maximize the benefits of such programs remain unknown. One such factor is how individuals should progress to higher levels of task difficulty within a balance-training program. Yet no investigators have directly compared different balance-training-progression styles. To compare an error-based progression (ie, advance when proficient at a task) with a repetition-based progression (ie, advance after a set amount of repetitions) style during a balance-training program in healthy individuals. Randomized controlled trial. Research laboratory. A total of 28 (16 women, 12 men) physically healthy young adults (age = 21.57 ± 3.95 years, height = 171.60 ± 11.03 cm, weight = 72.96 ± 16.18 kg, body mass index = 24.53 ± 3.7). All participants completed 12 supervised balance-training sessions over 4 weeks. Each session consisted of a combination of dynamic unstable-surface tasks that incorporated a BOSU ball and lasted about 30 minutes. Static balance from an instrumented force plate, dynamic balance as measured via the Star Excursion Balance Test, and ankle force production in all 4 cardinal planes of motion as measured with a handheld dynamometer before and after the intervention. Selected static postural-control outcomes, dynamic postural control, and ankle force production in all planes of motion improved (P < .05). However, no differences between the progression styles were observed (P > .05) for any of the outcome measures. A 4-week balance-training program consisting of dynamic unstable-surface exercises on a BOSU ball improved dynamic postural control and ankle force production in healthy young adults. These results suggest that an error-based balance-training program is comparable with but not superior to a repetition-based balance-training program in improving postural control and ankle force production in healthy young adults.

SciDAC's Earth System Grid Center for Enabling Technologies Semiannual Progress Report October 1, 2010 through March 31, 2011

DOE Office of Scientific and Technical Information (OSTI.GOV)

Williams, Dean N.

2011-04-02

This report summarizes work carried out by the Earth System Grid Center for Enabling Technologies (ESG-CET) from October 1, 2010 through March 31, 2011. It discusses ESG-CET highlights for the reporting period, overall progress, period goals, and collaborations, and lists papers and presentations. To learn more about our project and to find previous reports, please visit the ESG-CET Web sites: http://esg-pcmdi.llnl.gov/ and/or https://wiki.ucar.edu/display/esgcet/Home. This report will be forwarded to managers in the Department of Energy (DOE) Scientific Discovery through Advanced Computing (SciDAC) program and the Office of Biological and Environmental Research (OBER), as well as national and international collaborators andmore » stakeholders (e.g., those involved in the Coupled Model Intercomparison Project, phase 5 (CMIP5) for the Intergovernmental Panel on Climate Change (IPCC) 5th Assessment Report (AR5); the Community Earth System Model (CESM); the Climate Science Computational End Station (CCES); SciDAC II: A Scalable and Extensible Earth System Model for Climate Change Science; the North American Regional Climate Change Assessment Program (NARCCAP); the Atmospheric Radiation Measurement (ARM) program; the National Aeronautics and Space Administration (NASA), the National Oceanic and Atmospheric Administration (NOAA)), and also to researchers working on a variety of other climate model and observation evaluation activities. The ESG-CET executive committee consists of Dean N. Williams, Lawrence Livermore National Laboratory (LLNL); Ian Foster, Argonne National Laboratory (ANL); and Don Middleton, National Center for Atmospheric Research (NCAR). The ESG-CET team is a group of researchers and scientists with diverse domain knowledge, whose home institutions include eight laboratories and two universities: ANL, Los Alamos National Laboratory (LANL), Lawrence Berkeley National Laboratory (LBNL), LLNL, NASA/Jet Propulsion Laboratory (JPL), NCAR, Oak Ridge National Laboratory (ORNL), Pacific Marine Environmental Laboratory (PMEL)/NOAA, Rensselaer Polytechnic Institute (RPI), and University of Southern California, Information Sciences Institute (USC/ISI). All ESG-CET work is accomplished under DOE open-source guidelines and in close collaboration with the project's stakeholders, domain researchers, and scientists. Through the ESG project, the ESG-CET team has developed and delivered a production environment for climate data from multiple climate model sources (e.g., CMIP (IPCC), CESM, ocean model data (e.g., Parallel Ocean Program), observation data (e.g., Atmospheric Infrared Sounder, Microwave Limb Sounder), and analysis and visualization tools) that serves a worldwide climate research community. Data holdings are distributed across multiple sites including LANL, LBNL, LLNL, NCAR, and ORNL as well as unfunded partners sites such as the Australian National University (ANU) National Computational Infrastructure (NCI), the British Atmospheric Data Center (BADC), the Geophysical Fluid Dynamics Laboratory/NOAA, the Max Planck Institute for Meteorology (MPI-M), the German Climate Computing Centre (DKRZ), and NASA/JPL. As we transition from development activities to production and operations, the ESG-CET team is tasked with making data available to all users who want to understand it, process it, extract value from it, visualize it, and/or communicate it to others. This ongoing effort is extremely large and complex, but it will be incredibly valuable for building 'science gateways' to critical climate resources (such as CESM, CMIP5, ARM, NARCCAP, Atmospheric Infrared Sounder (AIRS), etc.) for processing the next IPCC assessment report. Continued ESG progress will result in a production-scale system that will empower scientists to attempt new and exciting data exchanges, which could ultimately lead to breakthrough climate science discoveries.« less

Aerospace nickel-cadmium cell separator qualifications program

NASA Technical Reports Server (NTRS)

Francis, R. W.; Haag, R. L.

1986-01-01

The present space qualified nylon separator, Pellon 2505 ML, is no longer available for aerospace nickel-cadmium (NiCd) cells. As a result of this anticipated unavailability, a joint Government program between the Air Force Space Division and the Naval Research Laboratory was established. Four cell types were procured with both the old qualified and the new unqualified separators. Acceptance, characterization, and life cycling tests are to be performed at the Naval Weapons Support Center, Crane, Ind. (NWSC/Crane). The scheduling and current status of this program are discussed and the progress of testing and available results are projected.

R&D Toward a Neutrino Factory and Muon Collider

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zisman, Michael S

2011-03-20

Significant progress has been made in recent years in R&D towards a neutrino factory and muon collider. The U.S. Muon Accelerator Program (MAP) has been formed recently to expedite the R&D efforts. This paper will review the U.S. MAP R&D programs for a neutrino factory and muon collider. Muon ionization cooling research is the key element of the program. The first muon ionization cooling demonstration experiment, MICE (Muon Ionization Cooling Experiment), is under construction now at RAL (Rutherford Appleton Laboratory) in the UK. The current status of MICE will be described.

New Brunswick Laboratory: Progress report, October 1987--September 1988

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

NBL has been tasked by the DOE Office of Safeguards and Security, Defense Programs (OSS/DP) to assure the application of accurate and reliable measurement technology for the safeguarding of special nuclear materials. NBL is fulfilling its mission responsibilities by identifying and addressing the measurement and measurement-related needs of the nuclear material safeguards community. These responsibilities are being addressed by activities in the following program areas: (1) reference and calibration materials, (2) measurement development, (3) measurement services, (4) measurement evaluation, (5) safeguards assessment, and (6) site-specific assistance. Highlights of each of these programs areas are provided in this summary.

The West Africa Field Epidemiology and Laboratory Training Program, a strategy to improve disease surveillance and epidemic control in West Africa

PubMed Central

Mutabaruka, Evariste; Sawadogo, Mamadou; Tarnagda, Zekiba; Ouédraogo, Lauren; Sangare, Lassana; Ousmane, Badolo; Ndjakani, Yassa; Namusisi, Olivia; Mukanga, David; Evering-Watley, Michele; Hounton, Sennen; Nsubuga, Peter

2011-01-01

The West Africa Field Epidemiology and Laboratory Training Program (WA-FELTP) which was established in September 2007, is an inter-country, competency-based, in-service and post -graduate training program in applied epidemiology and public health that builds the capacity to strengthen the surveillance and response system as well as epidemic control in the French-speaking countries where they are implemented. The overall purpose is to provide epidemiological and public health laboratory services to the public health systems at national, provincial, district and local levels. The program includes four countries: Burkina Faso, Mali, Niger, and Togo with an overarching goal to progressively cover all French speaking countries in West Africa through a phased-in approach. WA-FELTP's 2- year Master's program was launched in 2010 with 12 residents, three from each country, and consists of medical and veterinary doctors, pharmacists, and laboratory scientists. The training comprises 25% didactic sessions and 75% practical in-the-field mentored training. During the practical training, residents rovide service to their respective ministries of health and ministries of animal resources by contributing to outbreak investigations and activities that help to improve national surveillance systems at national, regional, district and local levels. The pressing challenges that the program must address consist of the lack of funds to support the second cohort of trainees, though trainee selection was completed, inadequate funds to support staff compensation, and shortage of funds to support trainees’ participation in critical activities in field epidemiology practice, and a need to develop a 5-year plan for sustainability. PMID:22359698

Laboratory Directed Research and Development 1998 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pam Hughes; Sheila Bennett eds.

1999-07-14

The Laboratory's Directed Research and Development (LDRD) program encourages the advancement of science and the development of major new technical capabilities from which future research and development will grow. Through LDRD funding, Pacific Northwest continually replenishes its inventory of ideas that have the potential to address major national needs. The LDRD program has enabled the Laboratory to bring to bear its scientific and technical capabilities on all of DOE's missions, particularly in the arena of environmental problems. Many of the concepts related to environmental cleanup originally developed with LDRD funds are now receiving programmatic support from DOE, LDRD-funded work inmore » atmospheric sciences is now being applied to DOE's Atmospheric Radiation Measurement Program. We also have used concepts initially explored through LDRD to develop several winning proposals in the Environmental Management Science Program. The success of our LDRD program is founded on good management practices that ensure funding is allocated and projects are conducted in compliance with DOE requirements. We thoroughly evaluate the LDRD proposals based on their scientific and technical merit, as well as their relevance to DOE's programmatic needs. After a proposal is funded, we assess progress annually using external peer reviews. This year, as in years past, the LDRD program has once again proven to be the major enabling vehicle for our staff to formulate new ideas, advance scientific capability, and develop potential applications for DOE's most significant challenges.« less

Progress toward improved leadership and management training in pathology.

PubMed

Weiss, Ronald L; Hassell, Lewis A; Parks, Eric R

2014-04-01

Competency gaps in leadership and laboratory management skills continue to exist between what training programs deliver and what recent graduates and future employers expect. A number of recent surveys substantiate this. Interest in delivering content in these areas is challenged by time constraints, the presence of knowledgeable faculty role models, and the necessary importance placed on diagnostic skills development, which overshadows any priority trainees have toward developing these skills. To describe the problem, the near-future horizon, the current solutions, and the recommendations for improving resident training in laboratory management. The demands of new health care delivery models and the value being placed on these skills by the Pathology Milestones and Next Accreditation System initiative of the Accreditation Council for Graduate Medical Education for training programs emphasizes their importance. This initiative includes 6 milestone competencies in laboratory management. Organizations like the American Society for Clinical Pathology, the American Pathology Foundation, the College of American Pathologists, and the Association of Pathology Chairs Program Directors Section recognize these competencies and are working to create new tools for training programs to deploy. It is our recommendation that (1) every training program develop a formal educational strategy for management training, (2) greater opportunity and visibility be afforded for peer-reviewed publications on management topics in mainstream pathology literature, and (3) pathology milestones-oriented tools be developed to assist program directors and their trainees in developing this necessary knowledge and skills.

Battery testing at Argonne National Laboratory

NASA Astrophysics Data System (ADS)

Deluca, W. H.; Gillie, K. R.; Kulaga, J. E.; Smaga, J. A.; Tummillo, A. F.; Webster, C. E.

Advanced battery technology evaluations are performed under simulated electric-vehicle operating conditions at the Analysis & Diagnostic Laboratory (ADL) of Argonne National Laboratory. The ADL results provide insight into those factors that limit battery performance and life. The ADL facilities include a test laboratory to conduct battery experimental evaluations under simulated application conditions and a post-test analysis laboratory to determine, in a protected atmosphere if needed, component compositional changes and failure mechanisms. This paper summarizes the performance characterizations and life evaluations conducted during FY-92 on both single cells and multi-cell modules that encompass six battery technologies (Na/S, Li/FeS, Ni/Metal-Hydride, Ni/Zn, Ni/Cd, Ni/Fe). These evaluations were performed for the Department of Energy, Office of Transportation Technologies, Electric and Hybrid Propulsion Division, and the Electric Power Research Institute. The ADL provides a common basis for battery performance characterization and life evaluations with unbiased application of tests and analyses. The results help identify the most promising R&D approaches for overcoming battery limitations, and provide battery users, developers, and program managers with a measure of the progress being made in battery R&D programs, a comparison of battery technologies, and basic data for modeling.

Laboratory Directed Research and Development Program Activities for FY 2007.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Newman,L.

2007-12-31

Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal year 2007 budget was $515 million. There are about 2,600 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annuallymore » in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development', April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. In accordance this is our Annual Report in which we describe the Purpose, Approach, Technical Progress and Results, and Specific Accomplishments of all LDRD projects that received funding during Fiscal Year 2007. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new 'fundable' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research 'which could lead to new programs, projects, and directions' for the Laboratory. We explicitly indicate that research conducted under the LDRD Program should be highly innovative, and an element of high risk as to success is acceptable. In the solicitation for new proposals for Fiscal Year 2007 we especially requested innovative new projects in support of RHIC and the Light Source and any of the Strategic Initiatives listed at the LDRD web site. These included support for NSLS-II, RHIC evolving to a quantum chromo dynamics (QCD) lab, nanoscience, translational and biomedical neuroimaging, energy and, computational sciences. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new science and technology ideas, which becomes a major factor in achieving and maintaining staff excellence and a means to address national needs within the overall mission of the DOE and BNL.« less

Secondary Education Through Health -- environmental health curriculum: A Superfund science literacy outreach project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sherman, L.R.

1996-12-31

Inner-city high school students are disproportionately affected by health problems that stem from environmental conditions. Also, they are not adequately prepared in Science -- especially in the concepts, methods, and procedures of environmental-health science research -- and are generally unaware of the career opportunities in this field. A Superfund program was developed to increase Science literacy and expand career knowledge in environmental health among a cohort of minority high school students from New York City. The year-round program features lectures, laboratory tours, seminars, investigations, and research taught by faculty and Superfund investigators at Mount Sinai`s Environmental Health Sciences Center. Themore » students made remarkable progress in terms of gaining environmental health knowledge, laboratory and scientific research skills, and awareness of environmental health careers.« less

Assessment of the Cast Stone Low-Temperature Waste Form Technology Coupled with Technetium Removal - 14379

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, Christopher F.; Rapko, Brian M.; Serne, R. Jeffrey

2014-03-03

The U.S. Department of Energy Office of Environmental Management (EM) is engaging the national laboratories to provide the scientific and technological rigor to support EM program and project planning, technology development and deployment, project execution, and assessment of program outcomes. As an early demonstration of this new responsibility, Pacific Northwest National Laboratory (PNNL) and Savannah River National Laboratory (SRNL) were chartered to implement a science and technology program addressing low-temperature waste forms for immobilization of DOE aqueous waste streams, including technetium removal as an implementing technology. As a first step, the laboratories examined the technical risks and uncertainties associated withmore » the Cast Stone waste immobilization and technetium removal projects at Hanford. Science and technology gaps were identified for work associated with 1) conducting performance assessments and risk assessments of waste form and disposal system performance, and 2) technetium chemistry in tank wastes and separation of technetium from waste processing streams. Technical approaches to address the science and technology gaps were identified and an initial sequencing priority was suggested. A subset of research was initiated in 2013 to begin addressing the most significant science and technology gaps. The purpose of this paper is to report progress made towards closing these gaps and provide notable highlights of results achieved to date.« less

Analytical Chemistry Laboratory. Progress report for FY 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

Green, D.W.; Boparai, A.S.; Bowers, D.L.

The purpose of this report is to summarize the activities of the Analytical Chemistry Laboratory (ACL) at Argonne National Laboratory (ANL) for Fiscal Year (FY) 1996. This annual report is the thirteenth for the ACL. It describes effort on continuing and new projects and contributions of the ACL staff to various programs at ANL. The ACL operates in the ANL system as a full-cost-recovery service center, but has a mission that includes a complementary research and development component: The Analytical Chemistry Laboratory will provide high-quality, cost-effective chemical analysis and related technical support to solve research problems of our clients --more » Argonne National Laboratory, the Department of Energy, and others -- and will conduct world-class research and development in analytical chemistry and its applications. Because of the diversity of research and development work at ANL, the ACL handles a wide range of analytical chemistry problems. Some routine or standard analyses are done, but the ACL usually works with commercial laboratories if our clients require high-volume, production-type analyses. It is common for ANL programs to generate unique problems that require significant development of methods and adaption of techniques to obtain useful analytical data. Thus, much of the support work done by the ACL is very similar to our applied analytical chemistry research.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stanislaus, Shirvel; Manweiler, Robert; Koetke, Donald

This report summarizes the research carried out by the faculty, staff and students of Valparaiso University (VU) during the 30-year period from 1986 to 2015 using funds provided by the Medium Energy Nuclear Physics program of the Department of Energy (DOE). Three faculty members led the VU research group during the lifetime of the research grant. The three principal investigators responsible for the research were: Dr. Donald Koetke (1986 – 2007), Dr. Robert Manweiler (2008 – 2010), and Dr. Shirvel Stanislaus (2011 – 2015). During this period we participated and contributed to the progress of the following experiments: 1. Themore » MEGA Experiment at Los Alamos National Laboratory (LAMPF E969). 2. The Crystal Ball Experiment at Brookhaven National Laboratory (BNL/AGS E906, E913). 3. The NuSea Experiment at Fermilab (FNAL E866). 4. The TWIST Experiment at TRIUMF (TRIUMF E614). 5. The STAR Experiment at RHIC. 6. The nEDM Experiment at Oak Ridge National Laboratory. In the following sections we briefly describe the goals of the above experiments and the contributions made by the Valparaiso University personnel towards the progress of each project.« less

Annual Progress Report and Report of Significant Accomplishments. Joint Services Electronics Program of the Edward L. Ginzton Laboratory.

DTIC Science & Technology

1983-08-01

Maccagno, and A. Miller, "Interaction of Acoustic Waves and Ferroelastic Domain Walls," Ferroelectrics (to be published). 3. J. A. Armstrong , et al...34 Preprint (November 1982). Also: Published in Electronics Letters, 18.A 999 (11 November 1982). 3513 S.A. Newton, J.E. Bowers, G. Kotler , Litton Systems, and

MOUND LABORATORY PROGRESS REPORT FOR DECEMBER 1960

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

Activities are reported in a program to investigate formulations and procedures which may lead to superior plastics and adhesives. In other work, processes for separating and purifying radioelements are being developed and supply sources are being evaluated. Research was initiated to determine the density, viscosity, thermal capacity, and thermal conductivity of Pu and Pu alloys for use in fast breeder reactors. (J.R.D.)

Factoring quality laboratory diagnosis into the malaria control agenda for sub-Saharan Africa.

PubMed

Aidoo, Michael

2013-09-01

Recent progress in malaria control in sub-Saharan Africa has been achieved primarily through provision of insecticide-treated nets, indoor residual spraying, and antimalarial drugs. Although these interventions are important, proper case identification and accurate measurement of their impact depend on quality diagnostic testing. Current availability of diagnostic testing for malaria in sub-Saharan Africa is inadequate to support disease management, prevention programs, and surveillance needs. Challenges faced include a dearth of skilled workforce, inadequate health systems infrastructure, and lack of political will. A coordinated approach to providing pre-service clinical and laboratory training together with systems that support a scale-up of laboratory services could provide means not only for effective malaria case management but also, management of non-malaria febrile illnesses, disease surveillance, and accurate control program evaluation. A synthesis of the challenges faced in ensuring quality malaria testing and how to include this information in the malaria control and elimination agenda are presented.

Report on the Progress of Weld Development of Irradiated Materials at the Oak Ridge National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Feng, Zhili; Miller, Roger G.; Chen, Jian

This report summarizes recent welding activities on irradiated alloys in the advanced welding facility at the Radiochemical Engineering Development Center of Oak Ridge National Laboratory and the development of post-weld characterization capabilities and procedures that will be critical for assessing the ability of the advanced welding processes housed within the facility to make successful repairs on irradiated alloys. This facility and its capabilities were developed jointly by the U.S. Department of Energy, Office of Nuclear Energy, Light Water Reactor Sustainability Program and the Electric Power Research Institute, Long Term Operations Program (and the Welding and Repair Technology Center), with additionalmore » support from Oak Ridge National Laboratory. The significant, on-going effort to weld irradiated alloys with high Helium concentrations and comprehensively analyze the results will eventually yield validated repair techniques and guidelines for use by the nuclear industry in extending the operational lifetimes of nuclear power plants.« less

Sandia National Laboratories support of the Iraq Nuclear Facility Dismantlement and Disposal Program.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cochran, John Russell; Danneels, Jeffrey John

2009-03-01

Because of past military operations, lack of upkeep and looting there are now enormous radioactive waste problems in Iraq. These waste problems include destroyed nuclear facilities, uncharacterized radioactive wastes, liquid radioactive waste in underground tanks, wastes related to the production of yellow cake, sealed radioactive sources, activated metals and contaminated metals that must be constantly guarded. Iraq currently lacks the trained personnel, regulatory and physical infrastructure to safely and securely manage these facilities and wastes. In 2005 the International Atomic Energy Agency (IAEA) agreed to organize an international cooperative program to assist Iraq with these issues. Soon after, the Iraqmore » Nuclear Facility Dismantlement and Disposal Program (the NDs Program) was initiated by the U.S. Department of State (DOS) to support the IAEA and assist the Government of Iraq (GOI) in eliminating the threats from poorly controlled radioactive materials. The Iraq NDs Program is providing support for the IAEA plus training, consultation and limited equipment to the GOI. The GOI owns the problems and will be responsible for implementation of the Iraq NDs Program. Sandia National Laboratories (Sandia) is a part of the DOS's team implementing the Iraq NDs Program. This report documents Sandia's support of the Iraq NDs Program, which has developed into three principal work streams: (1) training and technical consultation; (2) introducing Iraqis to modern decommissioning and waste management practices; and (3) supporting the IAEA, as they assist the GOI. Examples of each of these work streams include: (1) presentation of a three-day training workshop on 'Practical Concepts for Safe Disposal of Low-Level Radioactive Waste in Arid Settings;' (2) leading GOI representatives on a tour of two operating low level radioactive waste disposal facilities in the U.S.; and (3) supporting the IAEA's Technical Meeting with the GOI from April 21-25, 2008. As noted in the report, there was significant teaming between the various participants to best help the GOI. On-the-ground progress is the focus of the Iraq NDs Program and much of the work is a transfer of technical and practical skills and knowledge that Sandia uses day-to-day. On-the-ground progress was achieved in July of 2008 when the GOI began the physical cleanup and dismantlement of the Active Metallurgical Testing Laboratory (LAMA) facility at Al Tuwaitha, near Baghdad.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shettel, D.L. Jr.; Langfeldt, S.L.; Youngquist, C.A.

This report presents a Hydrogeochemical and Stream Sediment Reconnaissance of the Christian NTMS Quadrangle, Alaska. In addition to this abbreviated data release, more complete data are available to the public in machine-readable form. These machine-readable data, as well as quarterly or semiannual program progress reports containing further information on the HSSR program in general, or on the Los Alamos National Laboratory portion of the program in particular, are available from DOE's Technical Library at its Grand Junction Area Office. Presented in this data release are location data, field analyses, and laboratory analyses of several different sample media. For the sakemore » of brevity, many field site observations have not been included in this volume; these data are, however, available on the magnetic tape. Appendices A through D describe the sample media and summarize the analytical results for each medium. The data have been subdivided by one of the Los Alamos National Laboratory sorting programs of Zinkl and others (1981a) into groups of stream-sediment, lake-sediment, stream-water, lake-water, and ground-water samples. For each group which contains a sufficient number of observations, statistical tables, tables of raw data, and 1:1,000,000 scale maps of pertinent elements have been included in this report. Also included are maps showing results of multivariate statistical analyses.« less

Building America Systems Integration Research Annual Report: FY 2012

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gestwick, M.

2013-05-01

This document is the Building America FY2012 Annual Report, which includes an overview of the Building America Program activities and the work completed by the National Renewable Energy Laboratory and the Building America industry consortia (the Building America teams). The annual report summarizes major technical accomplishments and progress towards U.S. Department of Energy Building Technologies Program's multi-year goal of developing the systems innovations that enable risk-free, cost effective, reliable and durable efficiency solutions that reduce energy use by 30%-50% in both new and existing homes.

ORNL superconducting technology program for electric power systems

NASA Astrophysics Data System (ADS)

Hawsey, R. A.

1994-04-01

The Oak Ridge National Laboratory (ORNL) Superconducting Technology Program is conducted as part of a national effort by the US Department of Energy's Office of Energy Efficiency and Renewable Energy to develop the technology base needed by US industry for commercial development of electric power applications of high-temperature superconductivity. The two major elements of this program are conductor development and applications development. This document describes the major research and development activities for this program together with related accomplishments. The technical progress reported was summarized from information prepared for the FY 1993 Annual Program Review held July 28--29, 1993. This ORNL program is highly leveraged by the staff and other resources of US industry and universities. In fact, nearly three-fourths of the ORNL effort is devoted to industrial competitiveness projects with private companies. Interlaboratory teams are also in place on a number of industry-driven projects. Patent disclosures, working group meetings, staff exchanges, and joint publications and presentations ensure that there is technology transfer to US industry. Working together, the collaborative teams are making rapid progress in solving the scientific and technical issues necessary for the commercialization of long lengths of practical high-temperature superconductor wire and wire products.

ORNL superconducting technology program for electric energy systems

NASA Astrophysics Data System (ADS)

Hawsey, R. A.

1993-02-01

The Oak Ridge National Laboratory (ORNL) Superconducting Technology Program is conducted as part of a national effort by the US Department of Energy's (DOE's) Office of Conservation and Renewable Energy to develop the technology base needed by US industry for commercial development of electric power applications of high-temperature superconductivity. The two major elements of this program are wire development and systems development. This document describes the major research and development activities for this program together with related accomplishments. The technical progress reported was summarized from information prepared for the FY-92 Peer Review of Projects, which was conducted by DOE's Office of Program Analysis, Office of Energy Research. This ORNL program is highly leveraged by the staff and other resources of US industry and universities. Interlaboratory teams are also in place on a number of industry-driven projects. Patent disclosures, working group meetings, staff exchanges, and joint publications and presentations ensure that there is technology transfer to US industry. Working together, the collaborative teams are making tremendous progress in solving the scientific and technical issues necessary for the commercialization of long lengths of practical high-temperature superconductor wire and wire products.

Health and Safety Research Division progress report, October 1, 1988--March 31, 1990

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1990-09-01

The Health and Safety Research Division (HASRD) of the Oak Ridge National Laboratory (ORNL) continues to maintain an outstanding program of basic and applied research displaying a high level of creativity and achievement as documented by awards, publications, professional service, and successful completion of variety of projects. Our focus is on human health and the scientific basis for measurement and assessment of health-related impacts of energy technologies. It is our custom to publish a division progress report every 18 months that summarizes our programmatic progress and other measures of achievement over the reporting period. Since it is not feasible tomore » summarize in detail all of our work over the period covered by this report (October 1, 1988, to March 30, 1990), we intend this document to point the way to the expensive open literature that documents our findings. During the reporting period the Division continued to maintain strong programs in its traditional areas of R D, but also achieved noteworthy progress in other areas. Much of the Division's work on site characterization, development of new field instruments, compilation of data bases, and methodology development fits into this initiative. Other new work in tunneling microscopy in support of DOE's Human Genome Program and the comprehensive R D work related to surface-enhanced Raman spectroscopy have attained new and exciting results. These examples of our progress and numerous other activities are highlighted in this report.« less

Development of advanced strain diagnostic techniques for reactor environments.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fleming, Darryn D.; Holschuh, Thomas Vernon,; Miller, Timothy J.

2013-02-01

The following research is operated as a Laboratory Directed Research and Development (LDRD) initiative at Sandia National Laboratories. The long-term goals of the program include sophisticated diagnostics of advanced fuels testing for nuclear reactors for the Department of Energy (DOE) Gen IV program, with the future capability to provide real-time measurement of strain in fuel rod cladding during operation in situ at any research or power reactor in the United States. By quantifying the stress and strain in fuel rods, it is possible to significantly improve fuel rod design, and consequently, to improve the performance and lifetime of the cladding.more » During the past year of this program, two sets of experiments were performed: small-scale tests to ensure reliability of the gages, and reactor pulse experiments involving the most viable samples in the Annulated Core Research Reactor (ACRR), located onsite at Sandia. Strain measurement techniques that can provide useful data in the extreme environment of a nuclear reactor core are needed to characterize nuclear fuel rods. This report documents the progression of solutions to this issue that were explored for feasibility in FY12 at Sandia National Laboratories, Albuquerque, NM.« less

Nuclear Physics Laboratory technical progress report, November 1, 1972-- November 1, 1973

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1973-11-01

The experimental program was divided into the areas of nuclear physics (charged-particle experiments, gamma-ray experiments andd beta decay, neutron time-of-flight experiments, x-ray fluorescence analysis, other activities), intermediate enengy physics, and apparatus and facility development. The energy- loss spectrograph, rotating-beam neutron time-of-flight spectrometer, and cyclotron and the rearch done using these facilities are described. The theoretical program has concentrated on the effects of two-step processes in nuclear reactions. The trace element analysis program continued, and a neutron beam for cancer therapy is being developed. Lists of publications and personnel are also included. (RWR)

Waste Isolation Safety Assessment Program. Technical progress report for FY-1978

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brandstetter, A.; Harwell, M.A.; Howes, B.W.

1979-07-01

Associated with commercial nuclear power production in the United States is the generation of potentially hazardous radioactive wastes. The Department of Energy (DOE) is seeking to develop nuclear waste isolation systems in geologic formations that will preclude contact with the biosphere of waste radionuclides in concentrations which are sufficient to cause deleterious impact on humans or their environments. Comprehensive analyses of specific isolation systems are needed to assess the expectations of meeting that objective. The Waste Isolation Safety Assessment Program (WISAP) has been established at the Pacific Northwest Laboratory (operated by Battelle Memorial Institute) for developing the capability of makingmore » those analyses. Progress on the following tasks is reported: release scenario analysis, waste form release rate analysis, release consequence analysis, sorption-desorption analysis, and societal acceptance analysis. (DC)« less

Energy resource alternatives competition. Progress report for the period February 1, 1975--December 31, 1975. [Space heating and cooling, hot water, and electricity for homes, farms, and light industry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Matzke, D.J.; Osowski, D.M.; Radtke, M.L.

1976-01-01

This progress report describes the objectives and results of the intercollegiate Energy Resource Alternatives competition. The one-year program concluded in August 1975, with a final testing program of forty student-built alternative energy projects at the Sandia Laboratories in Albuquerque, New Mexico. The goal of the competition was to design and build prototype hardware which could provide space heating and cooling, hot water, and electricity at a level appropriate to the needs of homes, farms, and light industry. The hardware projects were powered by such nonconventional energy sources as solar energy, wind, biologically produced gas, coal, and ocean waves. The competitionmore » rules emphasized design innovation, economic feasibility, practicality, and marketability. (auth)« less

INEL BNCT Research Program annual report, 1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

Venhuizen, J.R.

1993-05-01

This report is a summary of the progress and research produced for the Idaho National Engineering Laboratory Boron Neutron Capture Therapy (BNCT) Research Program for calendar year 1992. Contributions from all the principal investigators about their individual projects are included, specifically, chemistry (pituitary tumor targeting compounds, boron drug development including liposomes, lipoproteins, and carboranylalanine derivatives), pharmacology (murine screenings, toxicity testing, inductively coupled plasma-atomic emission spectroscopy (ICP-AES) analysis of biological samples), physics (radiation dosimetry software, neutron beam and filter design, neutron beam measurement dosimetry), and radiation biology (small and large animal models tissue studies and efficacy studies). Information on the potentialmore » toxicity of borocaptate sodium and boronophenylalanine is presented, results of 21 spontaneous-tumor-bearing dogs that have been treated with BNCT at the Brookhaven National Laboratory (BNL) Medical Research Reactor (BMRR) are discussed, and predictions for an epithermal-neutron beam at the Georgia Tech Research Reactor (GTRR) are shown. Cellular-level boron detection and localization by secondary ion mass spectrometry, sputter-initiated resonance ionization spectroscopy, low atomization resonance ionization spectroscopy, and alpha track are presented. Boron detection by ICP-AES is discussed in detail. Several boron carrying drugs exhibiting good tumor uptake are described. Significant progress in the potential of treating pituitary tumors with BNCT is presented. Measurement of the epithermal-neutron flux at BNL and comparison to predictions are shown. Calculations comparing the GTRR and BMRR epithermal-neutron beams are also presented. Individual progress reports described herein are separately abstracted and indexed for the database.« less

1990 Environmental Monitoring Report, Sandia National Laboratories, Albuquerque, New Mexico

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hwang, S.; Yeager, G.; Wolff, T.

1991-05-01

This 1990 report contains monitoring data from routine radiological and nonradiological environmental surveillance activities. Summaries of significant environmental compliance programs in progress such as National Environmental Policy Act (NEPA) documentation, environmental permits, environmental restoration, and various waste management programs for Sandia National Laboratories in Albuquerque (SNL, Albuquerque) are included. The maximum offsite dose impact was calculated to be 2.0 {times} 10{sup {minus}3} mrem. The total 50-mile population received a collective dose of 0.82 person-rem during 1990 from SNL, Albuquerque, operations. As in the previous year, the 1990 SNL operations had no adverse impact on the general public or on themore » environment. This report is prepared for the US Department of Energy in compliance with DOE Order 5400.1. 97 refs., 30 figs., 137 tabs.« less

Isotherm Sensor Calibration Program for Mars Science Laboratory Heat Shield Flight Data Analysis

NASA Technical Reports Server (NTRS)

Santos, Jose A.; Oishi, Tomo; Martinez, Ed R.

2011-01-01

Seven instrumented sensor plugs were installed on the Mars Science Laboratory heat shield in December 2008 as part of the Mars Science Laboratory Entry, Descent, and Landing Instrumentation (MEDLI) project. These sensor plugs contain four in-depth thermocouples and one Hollow aErothermal Ablation and Temperature (HEAT) sensor. The HEAT sensor follows the time progression of a 700 C isotherm through the thickness of a thermal protection system (TPS) material. The data can be used to infer char depth and, when analyzed in conjunction with the thermocouple data, the thermal gradient through the TPS material can also be determined. However, the uncertainty on the isotherm value is not well defined. To address this uncertainty, a team at NASA Ames Research Center is carrying out a HEAT sensor calibration test program. The scope of this test program is described, and initial results from experiments conducted in the laboratory to study the isotherm temperature of the HEAT sensor are presented. Data from the laboratory tests indicate an isotherm temperature of 720 C 60 C. An overview of near term arc jet testing is also given, including preliminary data from 30.48cm 30.48cm PICA panels instrumented with two MEDLI sensor plugs and tested in the NASA Ames Panel Test Facility. Forward work includes analysis of the arc jet test data, including an evaluation of the isotherm value based on the instant in time when it reaches a thermocouple depth.

Multidisciplinary research program directed toward utilization of solar energy through bioconversion of renewable resources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1980-07-01

Progress is reported in this multidisciplinary research program. Genetic selection of superior trees, physiological basis of vigor, tissue culture systems leading to cloning of diploid and haploid cell lines are discussed in the Program A report. The physiological basis of enhanced oleoresin formation in southern pines when treated with sublethal concentrations of the herbicide paraquat was investigated in Program B. In Program C, metabolic changes in the stems of slash pine, in vivo, after application with paraquat were determined. The use of phdoem and xylem tissue slices as a laboratory model for studying paraquat associated- and normal-terpene synthesis in pinesmore » is discussed. The biochemistry and physiology of methane formation from cellulose during anaerobic fermentation are discussed in the Program D report. (DMC)« less

Benchmarking in pathology: development of an activity-based costing model.

PubMed

Burnett, Leslie; Wilson, Roger; Pfeffer, Sally; Lowry, John

2012-12-01

Benchmarking in Pathology (BiP) allows pathology laboratories to determine the unit cost of all laboratory tests and procedures, and also provides organisational productivity indices allowing comparisons of performance with other BiP participants. We describe 14 years of progressive enhancement to a BiP program, including the implementation of 'avoidable costs' as the accounting basis for allocation of costs rather than previous approaches using 'total costs'. A hierarchical tree-structured activity-based costing model distributes 'avoidable costs' attributable to the pathology activities component of a pathology laboratory operation. The hierarchical tree model permits costs to be allocated across multiple laboratory sites and organisational structures. This has enabled benchmarking on a number of levels, including test profiles and non-testing related workload activities. The development of methods for dealing with variable cost inputs, allocation of indirect costs using imputation techniques, panels of tests, and blood-bank record keeping, have been successfully integrated into the costing model. A variety of laboratory management reports are produced, including the 'cost per test' of each pathology 'test' output. Benchmarking comparisons may be undertaken at any and all of the 'cost per test' and 'cost per Benchmarking Complexity Unit' level, 'discipline/department' (sub-specialty) level, or overall laboratory/site and organisational levels. We have completed development of a national BiP program. An activity-based costing methodology based on avoidable costs overcomes many problems of previous benchmarking studies based on total costs. The use of benchmarking complexity adjustment permits correction for varying test-mix and diagnostic complexity between laboratories. Use of iterative communication strategies with program participants can overcome many obstacles and lead to innovations.

Laboratory for Computer Science Progress Report 19, 1 July 1981-30 June 1982.

DTIC Science & Technology

1984-05-01

Multiprocessor Architectures 202 4. TRIX Operating System 209 5. VLSI Tools 212 ’SYSTEMATIC PROGRAM DEVELOPMENT, 221 1. Introduction 222 2. Specification...exploring distributed operating systems and the architecture of single-user powerful computers that are interconnected by communication networks. The...to now. In particular, we expect to experiment with languages, operating systems , and applications that establish the feasibility of distributed

Hot Dry Rock Geothermal Energy Development Program: Annual report, fiscal year 1985

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, D.W.; Franke, P.R.; Smith, M.C.

1987-01-01

The primary objective for the Hot Dry Rock Program at the Los Alamos National Laboratory during fiscal year 1985 was to complete the Phase 2 reservoir connection and to begin flow testing the resulting reservoir. The connection was achieved through redrilling one well and additional fracturing operations, and progress was made toward developing a detailed understanding of the fractured region through a variety of reservoir interrogation methods. Other accomplishments during the fiscal year included improvement of the high-temperature, inflatable, open-hole packer used to isolate sections of the uncased wellbore in collaboration with the Baker Corporation and the design and fabricationmore » of a high-temperature borehole acoustic televiewer in a cooperative program with a research institute in West Germany. Progress was also made in techniques for the collection and analysis of microseismic data. Reservoir-engineering activities and geochemical studies, as well as the more routine support activities, continued in FY85. 18 refs., 15 figs.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

BROOKHAVEN NATIONAL LABORTORY; PROJECT MANAGER BARBARA COX

Brookhaven National Laboratory (BNL) strives for excellence in both its science research and its facility operations. BNL manages its world-class scientific research with particular sensitivity to environmental and community issues through its internationally recognized Environmental Management System (EMS) and award-winning community relations program. The Site Environmental Report 2000 (SER) summarizes the status of the Laboratory's environmental programs and performance, including the steady progress towards cleaning up the Laboratory site and fully integrating environmental stewardship into all facets of BNL's mission. BNL's motto, ''Exploring Earth's Mysteries... Protecting its Future,'' describes how the Laboratory approaches its work, with balance between science andmore » the environment. One of the newest initiatives at the Laboratory, the Upton Ecological and Research Reserve, will permanently preserve 530 acres (212 hectares) of the Long Island Central Pine Barrens, a unique ecosystem of forests and wetlands. The Reserve sets aside 10% of BNL property for conservation and ecological research through a partnership between the U.S. Department of Energy (DOE) and the U.S. Fish and Wildlife Service. The Reserve provides habitat for approximately 27 endangered, threatened, or species of special concern, including the state-endangered eastern tiger salamander, state-threatened banded sunfish, and swamp darter, along with a number of other species found onsite, such as the wild turkey and red-tailed hawk.« less

Comparative Effects of Different Balance-Training–Progression Styles on Postural Control and Ankle Force Production: A Randomized Controlled Trial

PubMed Central

Cuğ, Mutlu; Duncan, Ashley; Wikstrom, Erik

2016-01-01

Context:  Despite the effectiveness of balance training, the exact parameters needed to maximize the benefits of such programs remain unknown. One such factor is how individuals should progress to higher levels of task difficulty within a balance-training program. Yet no investigators have directly compared different balance-training–progression styles. Objective:  To compare an error-based progression (ie, advance when proficient at a task) with a repetition-based progression (ie, advance after a set amount of repetitions) style during a balance-training program in healthy individuals. Design:  Randomized controlled trial. Setting:  Research laboratory. Patients or Other Participants:  A total of 28 (16 women, 12 men) physically healthy young adults (age = 21.57 ± 3.95 years, height = 171.60 ± 11.03 cm, weight = 72.96 ± 16.18 kg, body mass index = 24.53 ± 3.7). Intervention(s):  All participants completed 12 supervised balance-training sessions over 4 weeks. Each session consisted of a combination of dynamic unstable-surface tasks that incorporated a BOSU ball and lasted about 30 minutes. Main Outcome Measure(s):  Static balance from an instrumented force plate, dynamic balance as measured via the Star Excursion Balance Test, and ankle force production in all 4 cardinal planes of motion as measured with a handheld dynamometer before and after the intervention. Results:  Selected static postural-control outcomes, dynamic postural control, and ankle force production in all planes of motion improved (P < .05). However, no differences between the progression styles were observed (P > .05) for any of the outcome measures. Conclusions:  A 4-week balance-training program consisting of dynamic unstable-surface exercises on a BOSU ball improved dynamic postural control and ankle force production in healthy young adults. These results suggest that an error-based balance-training program is comparable with but not superior to a repetition-based balance-training program in improving postural control and ankle force production in healthy young adults. PMID:26878257

Savannah River Ecology Laboratory. Annual technical progress report of ecological research, period ending July 31, 1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-07-31

The Savannah River Ecology Laboratory (SREL) is a research unit of the University of Georgia (UGA) that is managed in conjunction with the University`s Institute of Ecology. The laboratory`s overall mission is to acquire and communicate knowledge of ecological processes and principles. SREL conducts basic and applied ecological research, as well as education and outreach programs, under an M&O contract with the US Department of Energy at the Savannah River Site. Significant accomplishments were made during the year ending July 31, 1994 in the areas of research, education and service. Reviewed in this document are research projects in the followingmore » areas: Environmental Operations Support (impacted wetlands, streams, trace organics, radioecology, database synthesis, wild life studies, zooplankton, safety and quality assurance); wood stork foraging and breeding ecology; defence waste processing facility; environmental risk assessment (endangered species, fish, ash basin studies); ecosystem alteration by chemical pollutants; wetlands systems; biodiversity on the SRS; Environmental toxicology; environmental outreach and education; Par Pond drawdown studies in wildlife and fish and metals; theoretical ecology; DOE-SR National Environmental Research Park; wildlife studies. Summaries of educational programs and publications are also give.« less

Savannah River Ecology Laboratory annual technical progress report of ecological research for the year ending July 31, 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, M.H.

1995-07-01

The Savannah River Ecology Laboratory (SREL) is a research unit of the University of Georgia (UGA). The overall mission of the Laboratory is to acquire and communicate knowledge of ecological processes and principles. SREL conducts basic and applied ecological research, as well as education and outreach programs, under a contract with the US Department of Energy (DOE) at the Savannah River Site near Aiken, South Carolina. Significant accomplishments were made during the past year in the areas of research, education and service. Major additions to SREL Facilities were completed that will enhance the Laboratory`s work in the future. Following severalmore » years of planning, opening ceremonies were held for the 5000 ft{sup 2} multi-purpose conference center that was funded by the University of Georgia Research Foundation (UGARF). The center is located on 68 acres of land that was provided by the US Department of Energy. This joint effort between DOE and UGARF supports DOE`s new initiative to develop partnerships with the private sector and universities. The facility is being used for scientific meetings and environmental education programs for students, teachers and the general public. A 6000 ft{sup 2} office and library addition to S@s main building officially opened this year, and construction plans are underway on a new animal care facility, laboratory addition, and receiving building.« less

Highly Integrated Quality Assurance – An Empirical Case

DOE Office of Scientific and Technical Information (OSTI.GOV)

Drake Kirkham; Amy Powell; Lucas Rich

2011-02-01

Highly Integrated Quality Assurance – An Empirical Case Drake Kirkham1, Amy Powell2, Lucas Rich3 1Quality Manager, Radioisotope Power Systems (RPS) Program, Idaho National Laboratory, P.O. Box 1625 M/S 6122, Idaho Falls, ID 83415-6122 2Quality Engineer, RPS Program, Idaho National Laboratory 3Quality Engineer, RPS Program, Idaho National Laboratory Contact: Voice: (208) 533-7550 Email: Drake.Kirkham@inl.gov Abstract. The Radioisotope Power Systems Program of the Idaho National Laboratory makes an empirical case for a highly integrated Quality Assurance function pertaining to the preparation, assembly, testing, storage and transportation of 238Pu fueled radioisotope thermoelectric generators. Case data represents multiple campaigns including the Pluto/New Horizons mission,more » the Mars Science Laboratory mission in progress, and other related projects. Traditional Quality Assurance models would attempt to reduce cost by minimizing the role of dedicated Quality Assurance personnel in favor of either functional tasking or peer-based implementations. Highly integrated Quality Assurance adds value by placing trained quality inspectors on the production floor side-by-side with nuclear facility operators to enhance team dynamics, reduce inspection wait time, and provide for immediate, independent feedback. Value is also added by maintaining dedicated Quality Engineers to provide for rapid identification and resolution of corrective action, enhanced and expedited supply chain interfaces, improved bonded storage capabilities, and technical resources for requirements management including data package development and Certificates of Inspection. A broad examination of cost-benefit indicates highly integrated Quality Assurance can reduce cost through the mitigation of risk and reducing administrative burden thereby allowing engineers to be engineers, nuclear operators to be nuclear operators, and the cross-functional team to operate more efficiently. Applicability of this case extends to any high-value, long-term project where traceability and accountability are determining factors.« less

Oral anatomy laboratory examinations in a physical therapy program.

PubMed

Fabrizio, Philip A

2013-01-01

The process of creating and administering traditional tagged anatomy laboratory examinations is time consuming for instructors and limits laboratory access for students. Depending on class size and the number of class, sections, creating, administering, and breaking down a tagged laboratory examination may involve one to two eight-hour days. During the time that a tagged examination is being created, student productivity may be reduced as the anatomy laboratory is inaccessible to students. Further, the type of questions that can be asked in a tagged laboratory examination may limit student assessment to lower level cognitive abilities and may limit the instructors' ability to assess the students' understanding of anatomical and clinical concepts. Anatomy is a foundational science in the Physical Therapy curriculum and a thorough understanding of anatomy is necessary to progress through the subsequent clinical courses. Physical therapy curricula have evolved to reflect the changing role of physical therapists to primary caregivers by introducing a greater scope of clinical courses earlier in the curriculum. Physical therapy students must have a thorough understanding of clinical anatomy early in the education process. However, traditional anatomy examination methods may not be reflective of the clinical thought processes required of physical therapy students. Traditional laboratory examination methods also reduce student productivity by limiting access during examination set-up and breakdown. To provide a greater complexity of questions and reduced overall laboratory time required for examinations, the Physical Therapy Program at Mercer University has introduced oral laboratory examinations for the gross anatomy course series. © 2012 American Association of Anatomists.

Recent progress in the NASA-Goddard Space Flight Center atomic hydrogen standards program

NASA Technical Reports Server (NTRS)

Reinhardt, V. S.

1981-01-01

At NASA Goddard Space Flight Center and through associated contractors, a broad spectrum of work is being carried out to develop improved hydrogen maser frequency standards for field use, improved experimental hydrogen maser frequency standards, and improved frequency and time distribution and measurement systems for hydrogen maser use. Recent progress in the following areas is reported: results on the Nr masers built by the Applied Physics Laboratory of Johns Hopkins University, the development of a low cost hydrogen maser at Goddard Space Flight Center, and work on a low noise phase comparison system and digitally phase locked crystal oscillator called the distribution and measurement system.

Plasmodium Sporozoite Biology.

PubMed

Frischknecht, Friedrich; Matuschewski, Kai

2017-05-01

Plasmodium sporozoite transmission is a critical population bottleneck in parasite life-cycle progression and, hence, a target for prophylactic drugs and vaccines. The recent progress of a candidate antisporozoite subunit vaccine formulation to licensure highlights the importance of sporozoite transmission intervention in the malaria control portfolio. Sporozoites colonize mosquito salivary glands, migrate through the skin, penetrate blood vessels, breach the liver sinusoid, and invade hepatocytes. Understanding the molecular and cellular mechanisms that mediate the remarkable sporozoite journey in the invertebrate vector and the vertebrate host can inform evidence-based next-generation drug development programs and immune intervention strategies. Copyright © 2017 Cold Spring Harbor Laboratory Press; all rights reserved.

Progress of research on water vapor lidar

NASA Technical Reports Server (NTRS)

Wilkerson, Thomas D.; Singh, U. N.

1989-01-01

Research is summarized on applications of stimulated Raman scattering (SRS) of laser light into near infrared wavelengths suitable for atmospheric monitoring. Issues addressed are conversion efficiency, spectral purity, optimization of operating conditions, and amplification techniques. A Raman cell was developed and built for the laboratory program, and is now available to NASA-Langley, either as a design or as a completed cell for laboratory or flight applications. The Raman cell has been approved for flight in NASA's DC-8 aircraft. The self-seeding SRS technique developed here is suggested as an essential improvement for tunable near-IR DIAL applications at wavelengths of order 1 micrometer or greater.

Laboratory activities involving transmissible spongiform encephalopathy causing agents

PubMed Central

Leunda, Amaya; Van Vaerenbergh, Bernadette; Baldo, Aline; Roels, Stefan; Herman, Philippe

2013-01-01

Since the appearance in 1986 of epidemic of bovine spongiform encephalopathy (BSE), a new form of neurological disease in cattle which also affected human beings, many diagnostic and research activities have been performed to develop detection and therapeutic tools. A lot of progress was made in better identifying, understanding and controlling the spread of the disease by appropriate monitoring and control programs in European countries. This paper reviews the recent knowledge on pathogenesis, transmission and persistence outside the host of prion, the causative agent of transmissible spongiform encephalopathies (TSE) in mammals with a particular focus on risk (re)assessment and management of biosafety measures to be implemented in diagnostic and research laboratories in Belgium. Also, in response to the need of an increasing number of European diagnostic laboratories stopping TSE diagnosis due to a decreasing number of TSE cases reported in the last years, decontamination procedures and a protocol for decommissioning TSE diagnostic laboratories is proposed. PMID:24055928

Kirtland Operations progress report, April--June 1991

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

Kirtland Operations (KO) is an integral part of EG G Energy Measurements, Inc., whose primary mission is to support the US Department of Energy's (DOE's) programs in weapons development and testing and in nuclear safeguards and security. KO performs much of its work in close coordination with and often at the technical direction of Sandia National Laboratories. In addition to aiding Sandia's weapons programs, KO provides a wide spectrum of technical support to other Sandia activities, particularly their safeguards, security, and treaty verification programs. Support is also provided to other elements of the Department of Energy community and to othermore » federal agencies, primarily in weapons testing and safeguards. This report documents our support to these programs from April to June 1991.« less

Kirtland Operations progress report, October--December 1991

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

Kirtland Operations (KO) is an integral part of EG G Energy Measurements, Inc., whose primary mission is to support the US Department of Energy's (DOE's) programs in weapons development and testing and in nuclear safeguards and security. KO performs much of its work in close coordination with and often at the technical direction of Sandia National Laboratories. In addition to aiding Sandia's weapons programs, KO provides a wide spectrum of technical support to other Sandia activities, particularly their safeguards, security, and treaty verification programs. Support is also provided to other elements of the Department of Energy community and to othermore » federal agencies, primarily in weapons testing and safeguards. This report documents our support to these programs from October to December 1991.« less

U.S. Army Aeromedical Research Laboratory Annual Progress Report Fiscal Year 2011

DTIC Science & Technology

2012-06-01

Manager Mr. J. Miller 6811 Avn Std Officer Mr. J. Ramiccio 6957 Library………………..6936 Manpower…………...6840 MARS Facility……….6990 S-1 .......………………6886 Visual...Services Blood Program (ASBP) blood drive, sponsored by Lyster Army Health Clinic and the 1-13th AVN RGT. A USAARL civilian employee is a

Georgetown University and Hampton University Prostate Cancer Undergraduate Fellowship Program

DTIC Science & Technology

2015-10-01

Tyanna Jones-Gray (Dr. Vicente Notario), Ms. Damara Miller (Dr. Eliot Rosen), Ms. Jasmine Hatcher-Moorman (Dr. MaryBeth Martin), and Mr. Isaiah Brown...undergraduate students: 1. The Hampton University undergraduates (Ms. Tyanna Jones-Gray, Ms. Damara Miller, Ms. Jasmine Hatcher-Moorman, and Mr...cancer progression. Dr. Martin’s lab has identified the environmental hormones referred to as metallo- hormones. In Dr. Martin’s laboratory, Jasmine

DOE Office of Scientific and Technical Information (OSTI.GOV)

Derrick, M.

These proceedings document a number of aspects of a big science facility and its impact on science, on technology, and on the continuing program of a major US research institution. The Zero Gradient Synchrotron (ZGS) was a 12.5 GeV weak focusing proton accelerator that operated at Argonne for fifteen years--from 1964 to 1979. It was a major user facility which led to new close links between the Laboratory and university groups: in the research program; in the choice of experiments to be carried out; in the design and construction of beams and detectors; and even in the Laboratory management. Formore » Argonne, it marked a major move from being a Laboratory dominated by nuclear reactor development to one with a stronger basic research orientation. The present meeting covered the progress in accelerator science, in the applications of technology pioneered or developed by people working at the ZGS, as well as in physics research and detector construction. At this time, when the future of the US research programs in science is being questioned as a result of the ending of the Cold War and plans to balance the Federal budget, the specific place of the National Laboratories in the spectrum of research activities is under particular examination. This Symposium highlights one case history of a major science program that was completed more than a decade ago--so that the further developments of both the science and the technology can be seen in some perspective. The subsequent activities of the people who had worked in the ZGS program as well as the redeployment of the ZGS facilities were addressed. Selected papers are indexed separately for inclusion in the Energy Science and Technology Database.« less

The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chesler, Elissa J; Branstetter, Lisa R; Churchill, Gary A

2008-01-01

Complex traits and disease co-morbidity in humans and in model organisms are the result of naturally occurring polymorphisms that interact with each other and with the environment. To ensure the availability of the resources needed to investigate biomolecular networks and ultimately systems level phenotypes, we have initiated breeding of a new genetic reference population of mice, the Collaborative Cross. This population has been designed to optimally support systems genetics analysis. Its novel and important features include high levels of genetic diversity, a large population size to ensure sufficient power in high-dimensional studies, and high mapping precision through accumulation of independentmore » recombination events. Implementation of the Collaborative Cross has been in progress at the Oak Ridge National Laboratory (ORNL) since May 2005. This is achieved through a software assisted breeding program with fully traceable lineages, performed in a uniform environment. Currently, there are 650 lines in production with almost 200 lines over seven generations of inbreeding. Retired breeders enter a high-throughput phenotyping protocol and DNA samples are banked for analysis of recombination history, allele loss, and population structure. Herein we present a progress report of the Collaborative Cross breeding program at ORNL and a description of the kinds of investigations that this resource will support.« less

Space qualification of silicon carbide for mirror applications: progress and future objectives

NASA Astrophysics Data System (ADS)

Palusinski, Iwona A.; Ghozeil, Isaac

2006-09-01

Production of optical silicon carbide (SiC) for mirror applications continues to evolve and there are renewed plans to use this material in future space-based systems. While SiC has the potential for rapid and cost-effective manufacturing of large, lightweight, athermal optical systems, this material's use in mirror applications is relatively new and has limited flight heritage. This combination of drivers stresses the necessity for a space qualification program for this material. Successful space qualification will require independent collaboration to absorb the high cost of executing this program while taking advantage of each contributing group's laboratory expertise to develop a comprehensive SiC database. This paper provides an overview of the trends and progress in the production of SiC, and identifies future objectives such as non-destructive evaluation and space-effects modeling to ensure proper implementation of this material into future space-based systems.

Pacific Northwest Laboratory annual report for 1990 to the DOE Office of Energy Research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Park, J.F.

This report summarizes progress on OHER human health, biological, and general life sciences research programs conducted at PNL in FY 1990. The research develops the knowledge and scientific principles necessary to identify understand, and anticipate the long-term health consequences of energy-related radiation and chemicals. Our continuing emphasis is to decrease the uncertainty of health risk estimates from existing and developing energy-related technologies through an increased of understanding of how radiation and chemicals cause biological damage. The sequence of this report of PNL research reflects the OHER programmatic structure. The first section, on human health research, concerns epidemiological and statistical studiesmore » for assessing health risks. The next section contains reports of biological research in laboratory animals and in vitro cell systems, including research with radionuclides and chemicals. The general life sciences research section reports research conducted for the OHER human genome research program.« less

Core components of a comprehensive quality assurance program in anatomic pathology.

PubMed

Nakhleh, Raouf E

2009-11-01

In this article the core components of a comprehensive quality assurance and improvement plan are outlined. Quality anatomic pathology work comes with focus on accurate, timely, and complete reports. A commitment to continuous quality improvement and a systems approach with a persistent effort helps to achieve this end. Departments should have a quality assurance and improvement plan that includes a risk assessment of real and potential problems facing the laboratory. The plan should also list the individuals responsible for carrying out the program with adequate resources, a defined timetable, and annual assessment for progress and future directions. Quality assurance monitors should address regulatory requirements and be organized by laboratory division (surgical pathology, cytology, etc) as well as 5 segments (preanalytic, analytic, postanalytic phases of the test cycle, turn-around-time, and customer satisfaction). Quality assurance data can also be used to evaluate individual pathologists using multiple parameters with peer group comparison.

Development history of the Hybrid Test Vehicle

NASA Technical Reports Server (NTRS)

Trummel, M. C.; Burke, A. F.

1983-01-01

Phase I of a joint Department of Energy/Jet Propulsion Laboratory Program undertook the development of the Hybrid Test Vehicle (HTV), which has subsequently progressed through design, fabrication, and testing and evaluation phases. Attention is presently given to the design and test experience gained during the HTV development program, and a discussion is presented of the design features and performance capabilities of the various 'mule' vehicles, devoted to the separate development of engine microprocessor control, vehicle structure, and mechanical components, whose elements were incorporated into the final HTV design. Computer projections of the HTV's performance are given.

Waste-Management Education and Research Consortium (WERC) annual progress report, 1991--1992. Appendixes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-04-07

This report contains the following appendices: Appendix A - Requirements for Undergraduate Level; Appendix B - Requirements for Graduate Level; Appendix C - Graduate Degree In Environmental Engineering; Appendix D - Non-degree Certificate Program; Appendix E - Curriculum for Associate Degree Program; Appendix F - Curriculum for NCC Program; Appendix G - Information 1991 Teleconference Series; Appendix H - Information on 1992 Teleconference Series; Appendix I - WERC interactive Television Courses; Appendix J - WERC Research Seminar Series; Appendix K - Sites for Hazardous/Radioactive Waste Management Series; Appendix L- Summary of Technology Development of the Second Year; Appendix M -more » List of Major Publications Resulting from WERC; Appendix N - Types of Equipment at WERC Laboratories.« less

Waste-Management Education and Research Consortium (WERC) annual progress report, 1991--1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maji, A. K.; Thomson, Bruce M.; Samani, Zohrab A.

1992-04-07

This report contains the following appendices: Appendix A - Requirements for Undergraduate Level; Appendix B - Requirements for Graduate Level; Appendix C - Graduate Degree In Environmental Engineering; Appendix D - Non-degree Certificate Program; Appendix E - Curriculum for Associate Degree Program; Appendix F - Curriculum for NCC Program; Appendix G - Information 1991 Teleconference Series; Appendix H - Information on 1992 Teleconference Series; Appendix I - WERC interactive Television Courses; Appendix J - WERC Research Seminar Series; Appendix K - Sites for Hazardous/Radioactive Waste Management Series; Appendix L- Summary of Technology Development of the Second Year; Appendix M -more » List of Major Publications Resulting from WERC; Appendix N - Types of Equipment at WERC Laboratories.« less

Summer Student Research Presentations

NASA Technical Reports Server (NTRS)

Casey, Carol (Editor)

2005-01-01

In 2005, over 150 undergraduate students and first-year graduate students participated in a variety of research programs coordinated by the Jet Propulsion Laboratory Education Office in conjunction with the Caltech Student- Faculty Programs Office. The programs give students the opportunity to conduct research under the guidance of an experienced mentor for a 10-week period. Students gain valuable experience while contributing to the ongoing goals of JPL. Students are required to submit progress reports and an abstract, and to give an oral presentation of their projects to an audience of JPL staff and other students. This set of abstracts provides brief descriptions of the projects that were conducted by these students and their mentors. A schedule of student talks is also included.

Japanese plan for SSF utilization

NASA Technical Reports Server (NTRS)

Mizuno, Toshio

1992-01-01

The Japanese Experiment Module (JEM) program has made significant progress. The JEM preliminary design review was completed in July 1992; construction of JEM operation facilities has begun; and the micro-G airplane, drop shaft, and micro-G experiment rocket are all operational. The national policy for JEM utilization was also established. The Space Experiment Laboratory (SEL) opened in June '92 and will function as a user support center. Eight JEM multiuser facilities are in phase B, and scientific requirements are being defined for 17 candidate multiuser facilities. The National Joint Research Program is about to start. Precursor missions and early Space Station utilization activities are being defined. This paper summarizes the program in outline and graphic form.

United States Army physical readiness training: rationale and evaluation of the physical training doctrine.

PubMed

Knapik, Joseph J; Rieger, William; Palkoska, Frank; Van Camp, Steven; Darakjy, Salima

2009-07-01

This paper reviews the rationale and evaluations of Physical Readiness Training (PRT), the new U.S. Army physical training doctrine designed to improve soldiers' physical capability for military operations. The purposes of PRT are to improve physical fitness, prevent injuries, progressively train soldiers, and develop soldiers' self-confidence and discipline. The PRT follows the principles of progressive overload, regularity, specificity, precision, variety, and balance. Specificity was achieved by examining the standard list of military (warrior) tasks and determining 1) the physical requirements, 2) the fitness components involved, and 3) the training activities that most likely could improve the military tasks. Injury-prevention features include reduced running mileage, exercise variety (cross-training), and gradual, progressive training. In 3 military field studies, the overall adjusted risk of injury was 1.5-1.8 times higher in groups of soldiers performing traditional military physical training programs when compared with groups using a PRT program. Scores on the Army Physical Fitness Test were similar or higher in groups using PRT programs. In an 8-week laboratory study comparing PRT with a weightlifting/running program, both programs resulted in major improvements in militarily relevant tasks (e.g., 3.2-km walk/run with 32-kg load, 400-m run with 18-kg load, 5- to 30-second rushes to and from prone position, 80-kg casualty drag, obstacle course). When compared with traditional military physical training programs, PRT consistently resulted in fewer injuries and in equal or greater improvements in fitness and military task performance.

LABORATORY DIRECTED RESEARCH AND DEVELOPMENT ANNUAL REPORT TO THE DEPARTMENT OF ENERGY - DECEMBER 2006

DOE Office of Scientific and Technical Information (OSTI.GOV)

FOX, K.J.

Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's total annual budget has averaged about $460 million. There are about 2,500 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE)more » annually in March, as required by DOE Order 413.2B, ''Laboratory Directed Research and Development,'' April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy National Nuclear Security Administration Laboratories dated June 13, 2006. In accordance this is our Annual Report in which we describe the Purpose, Approach, Technical Progress and Results, and Specific Accomplishments of all LDRD projects that received funding during Fiscal Year 2006.« less

[Assessment of a supervision grid being used in the laboratories of cutaneous leishmaniasis in Morocco].

PubMed

El Mansouri, Bouchra; Amarir, Fatima; Hajli, Yamina; Fellah, Hajiba; Sebti, Faiza; Delouane, Bouchra; Sadak, Abderrahim; Adlaoui, El Bachir; Rhajaoui, Mohammed

2017-01-01

The aim of our study was to assess a standardized supervisory grid as a new supervision tool being used in the laboratories of leishmaniasis. We conducted a pilot trial to evaluate the ongoing performances of seven provincial laboratories, in four provinces in Morocco, over a period of two years, between 2006 and 2014. This study detailed the situation in provincial laboratories before and after the implementation of the supervisory grid. A total of twenty-one grids were analyzed. In 2006, the results clearly showed a poor performance of laboratories: need for training (41.6%), staff performing skin biopsy (25%), shortage of materials and reagents (65%), non-compliant document and local management (85%). Several corrective actions were conducted by the National Reference Laboratory (LNRL) of Leishmaniasis during the study period. In 2014, the LNRL recorded a net improvement of the performances of the laboratories. The need for training, the quality of the biopsy, the supply of tools and reagents were met and an effective coordination activity was established between the LNRL and the provincial laboratories. This trial shows the effectiveness of the grid as a high quality supervisory tool and as a cornerstone of making progress on fight programs against leishmaniases.

MIT Laboratory for Computer Science Progress Report, July 1984-June 1985

DTIC Science & Technology

1985-06-01

larger (up to several thousand machines) multiprocessor systems. This facility, funded by the newly formed Strategic Computing Program of the Defense...Szolovits, Group Leader R. Patil Collaborating Investigators M. Criscitiello, M.D., Tufts-New England Medical Center Hospital J. Dzierzanowski, Ph.D., Dept...COMPUTATION STRUCTURES Academic Staff J. B. Dennis, Group Leader Research Staff W. B. Ackerman G. A. Boughton W. Y-P. Lim Graduate Students T-A. Chu S

Laboratory for Computer Science Progress Report 21, July 1983-June 1984.

DTIC Science & Technology

1984-06-01

Systems 269 4. Distributed Consensus 270 5. Election of a Leader in a Distributed Ring of Processors 273 6. Distributed Network Algorithms 274 7. Diagnosis...multiprocessor systems. This facility, funded by the new!y formed Strategic Computing Program of the Defense Advanced Research Projects Agency, will enable...Academic Staff P. Szo)ovits, Group Leader R. Patil Collaborating Investigators M. Criscitiello, M.D., Tufts-New England Medical Center Hospital R

A Comparison of Computational Cognitive Models: Agent-Based Systems Versus Rule-Based Architectures

DTIC Science & Technology

2003-03-01

Java™ How To Program , Prentice Hall, 1999. Friedman-Hill, E., Jess, The Expert System Shell for the Java Platform, Sandia National Laboratories, 2001...transition from the descriptive NDM theory to a computational model raises several questions: Who is an experienced decision maker? How do you model the...progression from being a novice to an experienced decision maker? How does the model account for previous experiences? Are there situations where

Research program on fractured petroleum reservoirs. Task II - new phase formation and flow in porous media. Quarterly progress report, April 1, 1996--June 30, 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fang, F.; Firoozabadi, A.

We have developed a phenomenological model for critical condensate saturation. This model reveals that critical condensate saturation is a function of surface tension and contact angle hysteresis. On the other hand, residual oil saturation does not have such a dependency. Consequently, the selection of fluids in laboratory measurements for gas condensate systems should be made with care.

Adhesives: Test Method, Group Assignment, and Categorization Guide for High-Loading-Rate Applications

DTIC Science & Technology

2014-06-01

CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Robert Jensen, Daniel DeSchepper, David Flanagan, Wendy Kosik...lessons learned , or research purposes; these are generally long-term records.” Records will be kept in physical laboratory notebooks and digitally... learned ” could have potential value in addressing future research focus. Testing progression protocols beyond the third tier are intended for ARL

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

Progress is reported on fundamental research in: crystal physics, reactions at metal surfaces, spectroscopy of ionic media, structure of metals, theory of alloying, physical properties, sintering, deformation of crystalline solids, x ray diffraction, metallurgy of superconducting materials, and electron microscope studies. Long-randge applied research studies were conducted for: zirconium metallurgy, materials compatibility, solid reactions, fuel element development, mechanical properties, non-destructive testing, and high-temperature materials. Reactor development support work was carried out for: gas-cooled reactor program, molten-salt reactor, high-flux isotope reactor, space-power program, thorium-utilization program, advanced-test reactor, Army Package Power Reactor, Enrico Fermi fast-breeder reactor, and water desalination program. Other programmore » activities, for which research was conducted, included: thermonuclear project, transuraniunn program, and post-irradiation examination laboratory. Separate abstracts were prepared for 30 sections of the report. (B.O.G.)« less

Kirtland Operations progress report, October--December 1991

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

Kirtland Operations (KO) is an integral part of EG&G Energy Measurements, Inc., whose primary mission is to support the US Department of Energy`s (DOE`s) programs in weapons development and testing and in nuclear safeguards and security. KO performs much of its work in close coordination with and often at the technical direction of Sandia National Laboratories. In addition to aiding Sandia`s weapons programs, KO provides a wide spectrum of technical support to other Sandia activities, particularly their safeguards, security, and treaty verification programs. Support is also provided to other elements of the Department of Energy community and to other federalmore » agencies, primarily in weapons testing and safeguards. This report documents our support to these programs from October to December 1991.« less

Kirtland Operations progress report, April--June 1991

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

Kirtland Operations (KO) is an integral part of EG&G Energy Measurements, Inc., whose primary mission is to support the US Department of Energy`s (DOE`s) programs in weapons development and testing and in nuclear safeguards and security. KO performs much of its work in close coordination with and often at the technical direction of Sandia National Laboratories. In addition to aiding Sandia`s weapons programs, KO provides a wide spectrum of technical support to other Sandia activities, particularly their safeguards, security, and treaty verification programs. Support is also provided to other elements of the Department of Energy community and to other federalmore » agencies, primarily in weapons testing and safeguards. This report documents our support to these programs from April to June 1991.« less

Exploratory technology research program for electrochemical energy storage

NASA Astrophysics Data System (ADS)

Kinoshita, K.

1992-06-01

The U.S. Department of Energy's Office of Propulsion Systems provides support for an electrochemical energy storage program, that includes research and development (R&D) on advanced rechargeable batteries and fuel cells. A major goal of this program is to develop electrochemical power sources suitable for application in electric vehicles. The program centers on advanced systems that offer the potential for high performance and low life-cycle costs. The DOE Electrochemical Energy Storage Program is divided into two projects: the Electric Vehicle Advanced Battery Systems Development (EVABS) Program and the Exploratory Technology Research (ETR) Program. The EVABS Program management responsibility has been assigned to Sandia National Laboratory, and the Lawrence Berkeley Laboratory is responsible for management of the ETR Program. The EVABS and ETR Programs include an integrated matrix of R&D efforts designed to advance progress on several candidate electrochemical systems. The United States Advanced Battery Consortium (USABC), a tripartite undertaking between DOE, the U.S. automobile manufacturers and the Electric Power Research Institute (EPRI), was formed in 1991 to accelerate the development of advanced batteries for consumer EVs. The role of the ETR Program is to perform supporting research on the advanced battery systems under development by the USABC and EVABS Program, and to evaluate new systems with potentially superior performance, durability and/or cost characteristics. The specific goal of the ETR Program is to identify the most promising electrochemical technologies and transfer them to the USABC, the battery industry and/or the EVABS Program for further development and scaleup. This report summarizes the research, financial and management activities relevant to the ETR Program in FY 1991.

Laboratory evaluation of advanced battery technologies for electric vehicle applications

NASA Astrophysics Data System (ADS)

Deluca, W. H.; Kulaga, J. E.; Hogrefe, R. L.; Tummilo, A. F.; Webster, C. E.

1989-03-01

During 1988, battery technology evaluations were performed for the Department of Energy and Electric Power Research Institute at the Argonne Analysis and Diagnostic Laboratory. Cells and multicell modules from four developers were examined to determine their performance and life characteristics for electric vehicle propulsion applications. The results provide an interim measure of the progress being made in battery R and D programs, a comparison of battery technologies, and a source of basic data for modeling and continuing R and D. This paper summarizes the performance and life characterizations of twelve single cells and six 3- to 24-cell modules that encompass four technologies (Na/S, Ni/Fe, lead-acid, and Fe/Air).

Towards a controlled-phase gate using Rydberg-dressed atoms

NASA Astrophysics Data System (ADS)

Hankin, Aaron; Jau, Yuan-Yu; Biedermann, Grant

2014-05-01

We are implementing a controlled-phase gate based on singly trapped neutral atoms whose coupling is mediated by the dipole-dipole interaction of Rydberg states. An off-resonant laser field dresses ground state cesium atoms in a manner conditional on the Rydberg blockade mechanism, providing the required entangling interaction. We will present our progress toward implementing the controlled-phase gate with an analysis of possible sources of decoherence such as RF radiation from wireless communication devices. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000.

Sandia National Laboratories Advanced Simulation and Computing (ASC) software quality plan. Part 1: ASC software quality engineering practices, Version 2.0.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sturtevant, Judith E.; Heaphy, Robert; Hodges, Ann Louise

2006-09-01

The purpose of the Sandia National Laboratories Advanced Simulation and Computing (ASC) Software Quality Plan is to clearly identify the practices that are the basis for continually improving the quality of ASC software products. The plan defines the ASC program software quality practices and provides mappings of these practices to Sandia Corporate Requirements CPR 1.3.2 and 1.3.6 and to a Department of Energy document, ASCI Software Quality Engineering: Goals, Principles, and Guidelines. This document also identifies ASC management and software project teams responsibilities in implementing the software quality practices and in assessing progress towards achieving their software quality goals.

Environmental Sciences Division annual progress report for period ending September 30, 1990

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-04-01

The Environmental Sciences Division (ESD) of Oak Ridge National Laboratory (ORNL) conducts research on the environmental aspects of existing and emerging energy systems and applies this information to ensure that technology development and energy use are consistent with national environmental health and safety goals. Offering an interdisciplinary resource of staff and facilities to address complex environmental problems, the division is currently providing technical leadership for major environmental issues of national concern: (1) acidic deposition and related environmental effects, (2) effects of increasing concentrations of atmospheric CO{sub 2} and the resulting climatic changes to ecosystems and natural and physical resources, (3)more » hazardous chemical and radioactive waste disposal and remediation research and development, and (4) development of commercial biomass energy production systems. This progress report outlines ESD's accomplishments in these and other areas in FY 1990. Individual reports are processed separately for the data bases in the following areas: ecosystem studies; environmental analyses; environmental toxicology; geosciences; technical and administrative support; biofuels feedstock development program; carbon dioxide information analysis and research program; and environmental waste program.« less

Analytical Chemistry Division annual progress report for period ending December 31, 1989

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1990-04-01

The Analytical Chemistry Division of Oak Ridge National Laboratory (ORNL) is a large and diversified organization. As such, it serves a multitude of functions for a clientele that exists both in and outside of ORNL. These functions fall into the following general categories: Analytical Research, Development and Implementation; Programmatic Research, Development, and Utilization; and Technical Support. The Analytical Chemistry Division is organized into four major sections, each which may carry out any of the three types of work mentioned above. Chapters 1 through 4 of this report highlight progress within the four sections during the period January 1 to Decembermore » 31, 1989. A brief discussion of the division's role in an especially important environmental program is given in Chapter 5. Information about quality assurance, safety, and training programs is presented in Chapter 6, along with a tabulation of analyses rendered. Publications, oral presentations, professional activities, educational programs, and seminars are cited in Chapters 7 and 8. Approximately 69 articles, 41 proceedings, and 31 reports were published, and 151 oral presentations were given during this reporting period. Some 308,981 determinations were performed.« less

FY2007 Laboratory Directed Research and Development Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Craig, W W; Sketchley, J A; Kotta, P R

The Laboratory Directed Research and Development (LDRD) annual report for fiscal year 2007 (FY07) provides a summary of LDRD-funded projects for the fiscal year and consists of two parts: An introduction to the LDRD Program, the LDRD portfolio-management process, program statistics for the year, and highlights of accomplishments for the year. A summary of each project, submitted by the principal investigator. Project summaries include the scope, motivation, goals, relevance to Department of Energy (DOE)/National Nuclear Security Administration (NNSA) and Lawrence Livermore National Laboratory (LLNL) mission areas, the technical progress achieved in FY07, and a list of publications that resulted frommore » the research in FY07. Summaries are organized in sections by research category (in alphabetical order). Within each research category, the projects are listed in order of their LDRD project category: Strategic Initiative (SI), Exploratory Research (ER), Laboratory-Wide Competition (LW), and Feasibility Study (FS). Within each project category, the individual project summaries appear in order of their project tracking code, a unique identifier that consists of three elements. The first is the fiscal year the project began, the second represents the project category, and the third identifies the serial number of the proposal for that fiscal year.« less

Results of advanced battery technology evaluations for electric vehicle applications

NASA Astrophysics Data System (ADS)

Deluca, W. H.; Gillie, K. R.; Kulaga, J. E.; Smaga, J. A.; Tummillo, A. F.; Webster, C. E.

1992-10-01

Advanced battery technology evaluations are performed under simulated electric-vehicle operating conditions at the Analysis and Diagnostic Laboratory (ADL) of Argonne National Laboratory. The ADL results provide insight into those factors that limit battery performance and life. The ADL facilities include a test laboratory to conduct battery experimental evaluations under simulated application conditions and a post-test analysis laboratory to determine, in a protected atmosphere if needed, component compositional changes and failure mechanisms. This paper summarizes the performance characterizations and life evaluations conducted during 1991-1992 on both single cells and multi-cell modules that encompass eight battery technologies (Na/S, Li/MS (M=metal), Ni/MH, Ni/Cd, Ni/Zn, Ni/Fe, Zn/Br, and Pb-acid). These evaluations were performed for the Department of Energy, Office of Transportation Technologies, Electric and Hybrid Propulsion Division, and the Electric Power Research Institute. The ADL provides a common basis for battery performance characterization and life evaluations with unbiased application of tests and analyses. The results help identify the most-promising R&D approaches for overcoming battery limitations, and provide battery users, developers, and program managers with a measure of the progress being made in battery R&D programs, a comparison of battery technologies, and basic data for modeling.

2014 Fermilab Laboratory Directoed Research & Development Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

W. Wester

After initiation by the Fermilab Laboratory Director, a team from the senior Laboratory leadership and a Laboratory Directed Research and Development (LDRD) Advisory Committee developed an implementation plan for LDRD at Fermilab for the first time. This implementation was captured in the approved Fermilab 2014 LDRD Program Plan and followed directions and guidance from the Department of Energy (DOE) order, DOE O 413.2B, a “Roles, Responsibilities, and Guidelines, …” document, and examples of best practices at other DOE Office of Science Laboratories. At Fermilab, a FY14 midyear Call for Proposals was issued. A LDRD Selection Committee evaluated those proposals thatmore » were received and provided a recommendation to the Laboratory Director who approved seven LDRD projects. This Annual Report focuses on the status of those seven projects and provides an overview of the current status of LDRD at Fermilab. The seven FY14 LDRD approved projects had a date of initiation late in FY14 such that this report reflects approximately six months of effort approximately through January 2015. The progress of these seven projects, the subsequent award of six additional new projects beginning in FY15, and preparations for the issuance of the FY16 Call for Proposals indicates that LDRD is now integrated into the overall annual program at Fermilab. All indications are that LDRD is improving the scientific and technical vitality of the Laboratory and providing new, novel, or cutting edge projects carried out at the forefront of science and technology and aligned with the mission and strategic visions of Fermilab and the Department of Energy.« less

Student science enrichment training program. Progress report, June 1, 1991--May 31, 1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sandhu, S.S.

1992-04-21

Historically Black Colleges and Universities wing of the United States Department of Energy (DOE) provided funds to Claflin College, Orangeburg, S.C. To conduct a student Science Enrichment Training Program for a period of six weeks during 1991 summer. Thirty participants were selected from a pool of applicants, generated by the High School Seniors and Juniors and the Freshmen class of 1990-1991 at Claflin College. The program primarily focused on high ability students, with potential for Science, Mathematics and Engineering Careers. The major objectives of the program were W to increase the pool of well qualified college entering minority students whomore » will elect to go in Physical Sciences and Engineering and (II) to increase the enrollment in Chemistry and Preprofessional-Pre-Med, Pre-Dent, etc.-majors at Claflin College by including the Claflin students to participate in summer academic program. The summer academic program consisted of Chemistry and Computer Science training. The program placed emphasis upon laboratory experience and research. Visits to Scientific and Industrial laboratories were arranged. Guest speakers which were drawn from academia, industry and several federal agencies, addressed the participants on the future role of Science in the industrial growth of United States of America. The guest speakers also acted as role models for the participants. Several videos and films, emphasizing the role of Science in human life, were also screened.« less

Kirtland Operations progress report, January--March 1991

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

Kirtland Operations (KO) is an integral part of EG G Energy Measurements, Inc., whose primary mission is to support the US Department of Energy's (DOE's) programs in weapons development and testing and in nuclear safeguards and security. KO performs much of its work in close coordination with and often at the technical direction of Sandia National Laboratories. In addition to aiding Sandia's weapons programs, KO provides a wide spectrum of technical support to other Sandia activities, particularly their safeguards, security, and treaty verification programs. Support is also provided to other elements of the Department of Energy community and to othermore » federal agencies, primarily in weapons testing and safeguards. This report documents our support to these porgrams from January to March 1991.« less

Program director`s overview report for the Office of Health & Environmental Research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gilbert, D.

1994-02-01

LBL performs basic and applied research and develops technologies in support of the Office of Health and Environmental Research`s mission to explore and mitigate the long-term health and environmental consequences of energy use and to advance solutions to major medical challenges. The ability of the Laboratory to engage in this mission depends upon the strength of its core competencies. In addition, there are several key capabilities that are cross-cutting, or underlie, many of the core competencies. Attention is focused on the following: Facilities and resources; research management practices; research in progress; program accomplishments and research highlights; program orientation; work formore » non-OHER organizations DOE; critical issues; and resource orientation.« less

Analytical Chemistry Laboratory Progress Report for FY 1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

Green, D.W.; Boparai, A.S.; Bowers, D.L.

The purpose of this report is to summarize the activities of the Analytical Chemistry Laboratory (ACL) at Argonne National Laboratory (ANL) for Fiscal Year (FY) 1994 (October 1993 through September 1994). This annual report is the eleventh for the ACL and describes continuing effort on projects, work on new projects, and contributions of the ACL staff to various programs at ANL. The Analytical Chemistry Laboratory is a full-cost-recovery service center, with the primary mission of providing a broad range of analytical chemistry support services to the scientific and engineering programs at ANL. The ACL also has a research program inmore » analytical chemistry, conducts instrumental and methods development, and provides analytical services for governmental, educational, and industrial organizations. The ACL handles a wide range of analytical problems. Some routine or standard analyses are done, but it is common for the Argonne programs to generate unique problems that require significant development of methods and adaption of techniques to obtain useful analytical data. The ACL has four technical groups -- Chemical Analysis, Instrumental Analysis, Organic Analysis, and Environmental Analysis -- which together include about 45 technical staff members. Talents and interests of staff members cross the group lines, as do many projects within the ACL. The Chemical Analysis Group uses wet- chemical and instrumental methods for elemental, compositional, and isotopic determinations in solid, liquid, and gaseous samples and provides specialized analytical services. Major instruments in this group include an ion chromatograph (IC), an inductively coupled plasma/atomic emission spectrometer (ICP/AES), spectrophotometers, mass spectrometers (including gas-analysis and thermal-ionization mass spectrometers), emission spectrographs, autotitrators, sulfur and carbon determinators, and a kinetic phosphorescence uranium analyzer.« less

System for the growth of bulk SiC crystals by modified CVD techniques

NASA Technical Reports Server (NTRS)

Steckl, Andrew J.

1994-01-01

The goal of this program was the development of a SiC CVD growth of films thick enough to be useful as pseudo-substrates. The cold-walled CVD system was designed, assembled, and tested. Extrapolating from preliminary evaluation of SiC films grown in the system at relatively low temperatures indicates that the growth rate at the final temperatures will be high enough to make our approach practical. Modifications of the system to allow high temperature growth and cleaner growth conditions are in progress. This program was jointly funded by Wright Laboratory, Materials Directorate and NASA LeRC and monitored by NASA.

Applying Dataflow Architecture and Visualization Tools to In Vitro Pharmacology Data Automation.

PubMed

Pechter, David; Xu, Serena; Kurtz, Marc; Williams, Steven; Sonatore, Lisa; Villafania, Artjohn; Agrawal, Sony

2016-12-01

The pace and complexity of modern drug discovery places ever-increasing demands on scientists for data analysis and interpretation. Data flow programming and modern visualization tools address these demands directly. Three different requirements-one for allosteric modulator analysis, one for a specialized clotting analysis, and one for enzyme global progress curve analysis-are reviewed, and their execution in a combined data flow/visualization environment is outlined. © 2016 Society for Laboratory Automation and Screening.

Progress Report for the Robotic Intelligence Evaluation. Program Year 1: Developing Test Methodology for Anti-Rollover Systems

DTIC Science & Technology

2006-06-01

Scientific Research. 5PAM-Crash is a trademark of the ESI Group . 6MATLAB and SIMULINK are registered trademarks of the MathWorks. 14 maneuvers...Laboratory (ARL) to develop methodologies to evaluate robotic behavior algorithms that control the actions of individual robots or groups of robots...methodologies to evaluate robotic behavior algorithms that control the actions of individual robots or groups of robots acting as a team to perform a

A Methodology and Analysis for Cost-Effective Training in the AN/TSQ-73 Missile Minder

DTIC Science & Technology

1978-02-01

subsequent users must join the program in progress. 10. Languae Laboratory - Audio, Active - Compare Mode - Al audio presenta- tional device that distributes...initial performanceof the Fystem, change inputs to or elements within the system and 4note changes in the performance of the system. 33. Teaching...Any contest, governed by rules, between teams or individuals, where the contest is a dynamic model of some real system, and a computer is used in

Experiments in progress: The geography of science in the Atomic Energy Commission's peaceful uses of nuclear explosives program, 1956-1973

NASA Astrophysics Data System (ADS)

Kirsch, Scott Lawrence

From 1957 to 1973, the United States Atomic Energy Commission (AEC) actively pursued the "peaceful uses of nuclear explosives" through Project Plowshare. Nuclear excavation, the detonation of shallowly buried hydrogen bombs for massive earthmoving projects like harbors and canals, was considered the most promising of the Plowshare applications, and for a time, the most economically and technically "feasible." With a basis in and contributing to theory in critical human geography and science studies, the purpose of this dissertation is to examine the collisions of science, ideology, and politics which kept Plowshare designs alive--but only as "experiments in progress." That is, this research asks how the experimental program persisted in places like the national weapons laboratory in Livermore, California, and how its ideas were tested at the nuclear test site in Nevada, yet Plowshare was kept out of those spaces beyond AEC control. Primary research focuses on AEC-related archival materials collected from the Department of Energy Coordination and Information Center, Las Vegas, Nevada, and from the Lawrence Livermore National Laboratory, as well as the public discourse through which support for and opposition to Plowshare projects was voiced. Through critical analysis of Plowshare's grandiose "geographical engineering" schemes, I thus examine the complex relations between the social construction of science and technology, on one hand, and the social production of space, on the other.

Lawrence Livermore National Laboratory Safeguards and Security quarterly progress report to the US Department of Energy: Quarter ending December 31, 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davis, G.; Mansur, D.L.; Ruhter, W.D.

1994-01-01

The Lawrence Livermore National Laboratory (LLNL) carries out safeguards and security activities for the Department of Energy (DOE), Office of Safeguards and Security (OSS), as well as other organizations, both within and outside the DOE. This document summarizes the activities conducted for the OSS during the first quarter of fiscal year 1994 (October through December, 1993). The nature and scope of the activities carried out for OSS at LLNL require a broad base of technical expertise. To assure projects are staffed and executed effectively, projects are conducted by the organization at LLNL best able to supply the needed technical expertise.more » These projects are developed and managed by senior program managers. Institutional oversight and coordination is provided through the LLNL Deputy Director`s office. At present, the Laboratory is supporting OSS in five areas: (1) Safeguards Technology, (2) Safeguards and Decision Support, (3) Computer Security, (4) DOE Automated Physical Security, and (5) DOE Automated Visitor Access Control System. This report describes the activities in each of these five areas. The information provided includes an introduction which briefly describes the activity, summary of major accomplishments, task descriptions with quarterly progress, summaries of milestones and deliverables and publications published this quarter.« less

Lawrence Livermore National Laboratory safeguards and security quarterly progress report to the U.S. Department of Energy. Quarter ending December 31, 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davis, G.; Mansur, D.L.; Ruhter, W.D.

The Lawrence Livermore National Laboratory (LLNL) carries out safeguards and security activities for the Department of Energy (DOE), Office of Safeguards and Security (OSS), as well as other organizations, both within and outside the DOE. This document summarizes the activities conducted for the OSS during the First Quarter of Fiscal Year 1997 (October through December, 1996). The nature and scope of the activities carried out for OSS at LLNL require a broad base of technical expertise. To assure projects are staffed and executed effectively, projects are conducted by the organization at LLNL best able to supply the needed technical expertise.more » These projects are developed and managed by senior program managers. Institutional oversight and coordination is provided through the LLNL Deputy Director`s office. At present, the Laboratory is supporting OSS in four areas: (1) safeguards technology; (2) safeguards and material accountability; (3) computer security--distributed systems; and (4) physical and personnel security support. The remainder of this report describes the activities in each of these four areas. The information provided includes an introduction which briefly describes the activity, summary of major accomplishments, task descriptions with quarterly progress, summaries of milestones and deliverables and publications published this quarter.« less

The Application of System Dynamics to the Integration of National Laboratory Research and K-12 Education

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mills, James Ignatius; Zounar Harbour, Elda D

2001-08-01

The Idaho National Engineering and Environmental Laboratory (INEEL) is dedicated to finding solutions to problems related to the environment, energy, economic competitiveness, and national security. In an effort to attract and retain the expertise needed to accomplish these challenges, the INEEL is developing a program of broad educational opportunities that makes continuing education readily available to all laboratory employees, beginning in the K–12 environment and progressing through post-graduate education and beyond. One of the most innovative educational approaches being implemented at the laboratory is the application of STELLA© dynamic learning environments, which facilitate captivating K–12 introductions to the complex energymore » and environmental challenges faced by global societies. These simulations are integrated into lesson plans developed by teachers in collaboration with INEEL scientists and engineers. This approach results in an enjoyable and involved learning experience, and an especially positive introduction to the application of science to emerging problems of great social and environmental consequence.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Looney,J.P.; Fox, K.

Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that maintains a primary mission focus the physical sciences, energy sciences, and life sciences, with additional expertise in environmental sciences, energy technologies, and national security. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal year 2008 budget was $531.6 million. There are about 2,800 employees, and another 4,300 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to themore » U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development,' April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Developlnent at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. Accordingly, this is our Annual Report in which we describe the Purpose, Approach, Technical Progress and Results, and Specific Accomplishments of all LDRD projects that received funding during Fiscal Year 2008. BNL expended $12 million during Fiscal Year 2008 in support of 69 projects. The program has two categories, the annual Open Call LDRDs and Strategic LDRDs, which combine to meet the overall objectives of the LDRD Program. Proposals are solicited annually for review and approval concurrent with the next fiscal year, October 1. For the open call for proposals, an LDRD Selection Committee, comprised of the Associate Laboratory Directors (ALDs) for the Scientific Directorates, an equal number of scientists recommended by the Brookhaven Council, plus the Assistant Laboratory Director for Policy and Strategic Planning, review the proposals submitted in response to the solicitation. The Open Can LDRD category emphasizes innovative research concepts with limited management filtering to encourage the creativity of individual researchers. The competition is open to all BNL staff in programmatic, scientific, engineering, and technical support areas. Researchers submit their project proposals to the Assistant Laboratory Director for Policy and Strategic Planning. A portion of the LDRD budget is held for the Strategic LDRD (S-LDRD) category. Projects in this category focus on innovative R&D activities that support the strategic agenda of the Laboratory. The Laboratory Director entertains requests or articulates the need for S-LDRD funds at any time. Strategic LDRD Proposals also undergo rigorous peer review; the approach to review is tailored to the size and scope of the proposal. These Projects are driven by special opportunities, including: (1) Research project(s) in support of Laboratory strategic initiatives as defined and articulated by the Director; (2) Research project(s) in support of a Laboratory strategic hire; (3) Evolution of Program Development activities into research and development activities; and (4) ALD proposal(s) to the Director to support unique research opportunities. The goals and objectives of BNL's LDRD Program can be inferred fronl the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new 'fundable' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research 'which could lead to new programs, projects, and directions' for the Laboratory. We explicitly indicate that research conducted under the LDRD Program should be highly innovative, and an element of high risk as to success is acceptable. To be one of the premier DOE National Laboratories, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new science and technology ideas, which becomes a major factor in achieving and maintaining staff excellence and a means to address National needs within the overall mission of the DOE and BNL.« less

Cyclin-dependent kinase regulates the length of S phase through TICRR/TRESLIN phosphorylation.

PubMed

Sansam, Courtney G; Goins, Duane; Siefert, Joseph C; Clowdus, Emily A; Sansam, Christopher L

2015-03-01

S-phase cyclin-dependent kinases (CDKs) stimulate replication initiation and accelerate progression through the replication timing program, but it is unknown which CDK substrates are responsible for these effects. CDK phosphorylation of the replication factor TICRR (TopBP1-interacting checkpoint and replication regulator)/TRESLIN is required for DNA replication. We show here that phosphorylated TICRR is limiting for S-phase progression. Overexpression of a TICRR mutant with phosphomimetic mutations at two key CDK-phosphorylated residues (TICRR(TESE)) stimulates DNA synthesis and shortens S phase by increasing replication initiation. This effect requires the TICRR region that is necessary for its interaction with MDM two-binding protein. Expression of TICRR(TESE) does not grossly alter the spatial organization of replication forks in the nucleus but does increase replication clusters and the number of replication forks within each cluster. In contrast to CDK hyperactivation, the acceleration of S-phase progression by TICRR(TESE) does not induce DNA damage. These results show that CDK can stimulate initiation and compress the replication timing program by phosphorylating a single protein, suggesting a simple mechanism by which S-phase length is controlled. © 2015 Sansam et al.; Published by Cold Spring Harbor Laboratory Press.

Overview of ARPA low-cost ceramic composites (LC{sup 3}) program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adler, P.N.

1996-12-31

Grumman is currently leading an approximate $10M ARPA cost-shared program aimed at developing low-cost fabrication methodology for manufacturing ceramic matrix composite (CMC) structural components. One of the program goals is to demonstrate the effectiveness of an advanced materials partnership. A vertically integrated collaboration now exists that combines the talents of three large private sector organizations, two smaller private sector organizations, three universities, and three federal government laboratories. Work in progress involves preceramic polymer (Blackglas{trademark}) CMC materials technology, RTM and pyrolysis process modeling & simulation, and utilization of low-cost approaches for fabricating a CMC demonstration engine seal component. This paper reviewsmore » the program organization, functioning, and some of the highlights of the technical work, which is of interest to the DoD as well as the commercial sector.« less

Photovoltaic Subcontract Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Surek, Thomas; Catalano, Anthony

1993-03-01

This report summarizes the fiscal year (FY) 1992 progress of the subcontracted photovoltaic (PV) research and development (R D) performed under the Photovoltaic Advanced Research and Development Project at the National Renewable Energy Laboratory (NREL)-formerly the Solar Energy Research Institute (SERI). The mission of the national PV program is to develop PV technology for large-scale generation of economically competitive electric power in the United States. The technical sections of the report cover the main areas of the subcontract program: the Crystalline Materials and Advanced Concepts project, the Polycrystalline Thin Films project, Amorphous Silicon Research project, the Photovoltaic Manufacturing Technology (PVMaT)more » project, PV Module and System Performance and Engineering project, and the PV Analysis and Applications Development project. Technical summaries of each of the subcontracted programs provide a discussion of approaches, major accomplishments in FY 1992, and future research directions.« less

(Boiling water reactor (BWR) CORA experiments)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ott, L.J.

To participate in the 1990 CORA Workshop at Kernforschungszentrum Karlsruhe (KfK) GmbH, Karlsruhe, FRG, on October 1--4, and to participate in detailed discussions on October 5 with the KfK CORA Boiling Water Reactor (BWR) experiments. The traveler attended the 1990 CORA Workshop at KfK, FRG. Participation included the presentation of a paper on work performed by the Boiling Water Reactor Core Melt Progression Phenomena Program at Oak Ridge National Laboratory (ORNL) on posttest analyses of CORA BWR experiments. The Statement of Work (November 1989) for the BWR Core Melt Progression Phenomena Program provides for pretest and posttest analyses of themore » BWR CORA experiments performed at KfK. Additionally, it is intended that ORNL personnel participate in the planning process for future CORA BWR experiments. For these purposes, meetings were held with KfK staff to discuss such topics as (1) experimental test schedule, (2) BWR test conduct, (3) perceived BWR experimental needs, and (4) KfK operational staff needs with respect to ORNL support. 19 refs.« less

Exploratory Technology Research Program for electrochemical energy storage

NASA Astrophysics Data System (ADS)

Kinoshita, Kim

1994-09-01

The U.S. Department of Energy's Office of Propulsion Systems provides support for an Electrochemical Energy Storage Program, that includes research and development (R&D) on advanced rechargeable batteries and fuel cells. A major goal of this program is to develop electrochemical power sources suitable for application in electric vehicles (EV's). The program centers on advanced systems that offer the potential for high performance and low life-cycle costs, both of which are necessary to permit significant penetration into commercial markets. The DOE Electrochemical Energy Storage Program is divided into two projects: the Electric Vehicle Advanced Battery Systems (EVABS) Development Program and the Exploratory Technology Research (ETR) Program. The EVABS Program management responsibility has been assigned to Sandia National Laboratories (SNL); Lawrence Berkeley Laboratory (LBL) is responsible for management of the ETR Program. The EVABS and ETR Programs include an integrated matrix of R&D efforts designed to advance progress on selected candidate electrochemical systems. The United States Advanced Battery Consortium (USABC), a tripartite undertaking between DOE, the U.S. automobile manufacturers and the Electric Power Research Institute (EPRI), was formed in 1991 to accelerate the development of advanced batteries for consumer EV's. The role of the FIR Program is to perform supporting research on the advanced battery systems under development by the USABC and EVABS Program, and to evaluate new systems with potentially superior performance, durability and/or cost characteristics. The specific goal of the ETR Program is to identify the most promising electrochemical technologies and transfer them to the USABC, the battery industry and/or the EVABS Program for further development and scale-up. This report summarizes the research, financial and management activities relevant to the ETR Program in CY 1993.

Exploratory Technology Research Program for electrochemical energy storage

NASA Astrophysics Data System (ADS)

Kinoshita, Kim

1994-09-01

The U.S. Department of Energy's Office of Propulsion Systems provides support for an Electrochemical Energy Storage Program, that includes research and development (R&D) on advanced rechargeable batteries and fuel cells. A major goal of this program is to develop electrochemical power sources suitable for application in electric vehicles (EV's). The program centers on advanced systems that offer the potential for high performance and low life-cycle costs, both of which are necessary to permit significant penetration into commercial markets. The DOE Electrochemical Energy Storage Program is divided into two projects: the Electric Vehicle Advanced Battery Systems (EVABS) Development Program and the Exploratory Technology Research (ETR) Program. The EVABS Program management responsibility has been assigned to Sandia National Laboratories (SNL); Lawrence Berkeley Laboratory (LBL) is responsible for management of the FIR Program. The EVABS and ETR Programs include an integrated matrix of R&D efforts designed to advance progress on selected candidate electrochemical systems. The United States Advanced Battery Consortium (USABC), a tripartite undertaking between DOE, the U.S. automobile manufacturers and the Electric Power Research Institute (EPRI), was formed in 1991 to accelerate the development of advanced batteries for consumer EV's. The role of the FIR Program is to perform supporting research on the advanced battery systems under development by the USABC and EVABS Program, and to evaluate new systems with potentially superior performance, durability and/or cost characteristics. The specific goal of the ETR Program is to identify the most promising electrochemical technologies and transfer them to the USABC, the battery industry and/or the EVABS Program for further development and scale-up. This report summarizes the research, financial and management activities relevant to the ETR Program in CY 1993.

Progress and Potential

PubMed Central

Haspel, Richard L.; Olsen, Randall J.; Berry, Anna; Hill, Charles E.; Pfeifer, John D.; Schrijver, Iris; Kaul, Karen L.

2014-01-01

Context Genomic medicine is revolutionizing patient care. Physicians in areas as diverse as oncology, obstetrics, and infectious disease have begun using next-generation sequencing assays as standard diagnostic tools. Objective To review the role of pathologists in genomic testing as well as current educational programs and future training needs in genomic pathology. Data Sources Published literature as well as personal experience based on committee membership and genomic pathology curricular design. Conclusion Pathologists, as the directors of the clinical laboratories, must be prepared to integrate genomic testing into their practice. The pathology community has made significant progress in genomics-related education. A continued coordinated and proactive effort will ensure a future vital role for pathologists in the evolving health care system and also the best possible patient care. PMID:24678680

Annotated bibliography of radioactive waste management publications at Pacific Northwest Laboratory, January 1978 through July 1982. [831 abstracts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1982-09-01

This bibliography lists publications (831 abstracts) from the Pacific Northwest Laboratory's Department of Energy sponsored research and development programs from January 1978 through July of 1982. The abstracts are grouped in subject categories, as shown in the table of contents. Entries in the subject index also facilitate access by subject, e.g., High-Level Radioactive Wastes. Three indexes, each preceded by a brief description, are provided: personal author, subject, and report number. Cited are research reports, journal articles, books, patents, theses, and conference papers. Excluded are technical progress reports. Since 1978 the Nuclear Waste Management Quarterly Progress Report has been published undermore » the series number PNL-3000. Beginning in 1982, this publication has been issued semiannually, under the series number PNL-4250. This bibliography is the successor to two others, BNWL-2201 (covering the years 1965-1976) and PNL-4050 (1975-1978). It is intended to provide a useful reference to literature in waste management written or compiled by PNL staff.« less

Recent progress on external occulter technology for imaging exosolar planets

NASA Astrophysics Data System (ADS)

Kasdin, N. J.; Vanderbei, R. J.; Sirbu, D.; Samuels, J.; Shaklan, S.; Lisman, D.; Thomson, M.; Cady, E.; Martin, S.

Imaging planets orbiting nearby stars requires a system for suppressing the host starlight by at least ten orders of magnitude. One such approach uses an external occulter, a satellite flying far from the telescope and employing a large screen, or starshade, to suppress the incoming starlight. This trades the added complexity of building the precisely shaped starshade and flying it in formation against simplifications in the telescope since extremely precise wavefront control is no longer necessary. Much progress has been made recently in designing, testing and manufacturing starshade technology. In this paper we describe the design of starshades and report on recent accomplishments in manufacturing and measuring a prototype occulter petal as part of NASA's first Technology Development for Exoplanet Missions (TDEM) program. We demonstrate that the as-built petal is consistent with a full-size occulter achieving better than 10-10 contrast. We also discuss laboratory testing at the Princeton Occulter Testbed. These experiments use sub-scale, long-distance beam propagation to verify the diffraction analysis associated with occulter starlight suppression. We demonstrate roughly 10-10 suppression in the laboratory and discuss the important challenges and limitations.

1993-94-95 Kara sea field experiments and analysis. 1995 progress report to onr Arctic Nuclear Waste Assessment Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Phillips, G.W.; August, R.A.; King, S.E.

1996-01-14

This progress report covers field work and laboratory analysis efforts for quantifying the environmental threat of radioactive waste released in the Arctic seas adjacent to the former Soviet Union and for studying the various transport mechanisms by which this radioactivity could effect populations of the U.S. and other countries bordering the Arctic. We obtained water, sediment, biological samples and oceanographic data from several cruises to the Kara Sea and adjacent waters and conducted detailed laboratory analyses of the samples for radionuclides and physical biological properties. In addition, we obtained water and sediment samples and conducted on site low level radionuclidemore » analysis on the Angara, Yenisey River system which drains a major part of the Siberian industrial heartland and empties into the Kara Sea. We report on radionuclide concentrations, on radionuclide transport and scrubbing by sediments, on adsorption by suspended particles, on transport by surface and benthic boundary layer currents, on the effects of benthic and demersal organisms, on studies of long term monitoring in the Arctic, and on an interlaboratory calibration for radionuclide analysis.« less

Biotechnology by Design: An Introductory Level, Project-Based, Synthetic Biology Laboratory Program for Undergraduate Students.

PubMed

Beach, Dale L; Alvarez, Consuelo J

2015-12-01

Synthetic biology offers an ideal opportunity to promote undergraduate laboratory courses with research-style projects, immersing students in an inquiry-based program that enhances the experience of the scientific process. We designed a semester-long, project-based laboratory curriculum using synthetic biology principles to develop a novel sensory device. Students develop subject matter knowledge of molecular genetics and practical skills relevant to molecular biology, recombinant DNA techniques, and information literacy. During the spring semesters of 2014 and 2015, the Synthetic Biology Laboratory Project was delivered to sophomore genetics courses. Using a cloning strategy based on standardized BioBrick genetic "parts," students construct a "reporter plasmid" expressing a reporter gene (GFP) controlled by a hybrid promoter regulated by the lac-repressor protein (lacI). In combination with a "sensor plasmid," the production of the reporter phenotype is inhibited in the presence of a target environmental agent, arabinose. When arabinose is absent, constitutive GFP expression makes cells glow green. But the presence of arabinose activates a second promoter (pBAD) to produce a lac-repressor protein that will inhibit GFP production. Student learning was assessed relative to five learning objectives, using a student survey administered at the beginning (pre-survey) and end (post-survey) of the course, and an additional 15 open-ended questions from five graded Progress Report assignments collected throughout the course. Students demonstrated significant learning gains (p < 0.05) for all learning outcomes. Ninety percent of students indicated that the Synthetic Biology Laboratory Project enhanced their understanding of molecular genetics. The laboratory project is highly adaptable for both introductory and advanced courses.

Update on the U.S. Army TARDEC Power and Energy P&E SIL Program: Progress since the 6th AECV (June 2005 to Present)

DTIC Science & Technology

2007-06-01

John Kajs and Marc Compere , Power System Upgrade for TARDEC Systems Integration Lab, Proceedings of the 6th AECV Conference, Bath, UK, June 13-16...2005. 7 Miguel Simon, Marc Compere , Thomas Connolly, Charles Lors, Wilford Smith, and Mark Brudnak, “Hybrid Electric Power and Energy Laboratory...FL, April 2006 10 Mark Brudnak, Mike Pozolo, Victor Paul, Syed Mohammad, Wilford Smith, Marc Compere , Jarrett Goodell, Dale Holtz, Todd Mortsfield

Proceedings of the DARPA/AFWAL Review of Progress in Quantitative Nondestructive Evaluation, held 14-18 July 1980, Scripps Institution of Oceanography, La Jolla, California.

DTIC Science & Technology

1981-09-01

them presumably as plan proceeds. A work package description is in- an adjunct in ongoing failure studies . It would cluded for each block on the...Furthermore, the two limiting cases in the unit theoreti-al and laboratory results, lhe most amplitude study are the square wave and the ex - important reason is...of Denver Research Institute ...................................................... 87 STUDY PROGRAM FOR ENCAPSULATION MATERIALS INTERFACE FOR LOW-COST

First Year Projects and Activities of the Environmental Remote Sensing Applications Laboratory (ERSAL)

NASA Technical Reports Server (NTRS)

Poulton, C. E.; Faulkner, D. P.

1973-01-01

Activities, pilot projects, and research that will effectively close the gap between state-of-the-art remote sensing technology and the potential users and beneficiaries of this technological and scientific progress are discussed in light of the first year of activity. A broad spectrum of resource and man-environment problems are described in terms of the central thrust of the first-year program to support land use planning decisions with information derived from the interpretation of NASA highlight and satellite imagery.

Pacific Northwest Laboratory annual report for 1991 to the DOE Office of Energy Research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Park, J.F.

1992-09-01

This report summarizes progress in OHER biological research and general life sciences research programs conducted conducted at PNL in FLY 1991. The research develops the knowledge and scientific principles necessary to identify, understand, and anticipate the long- term health consequences of energy-related radiation and chemicals. Our continuing emphasis is to decrease the uncertainty of health risk estimates from existing and newly developed energy-related technologies through an increased understanding of the ways in which radiation and chemicals cause biological damage.

Progress Report for the Joint Services Electronic Program for the Period April 1, 1989 through March 31, 1990 (Coordinated Science Laboratory, University of Illinois at Urbana-Champaign)

DTIC Science & Technology

1990-06-30

since the projected ion range is of the order of lattice constants. Thus, we have extended our thermal-dopant incorporation model and have developed...bombardment results in residual lattice damage, which degrades electrical and optical properties. Obviously, at sufficiently high acceleration energies...understand the details of collisional lattice dynamics and ion-induced defect for- mation and annihilation. In addition, the simulations are providing, for

Laboratory Directed Research and Development FY2008 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kammeraad, J E; Jackson, K J; Sketchley, J A

The Laboratory Directed Research and Development (LDRD) Program, authorized by Congress in 1991 and administered by the Institutional Science and Technology Office at Lawrence Livermore, is our primary means for pursuing innovative, long-term, high-risk, and potentially high-payoff research that supports the full spectrum of national security interests encompassed by the missions of the Laboratory, the Department of Energy, and National Nuclear Security Administration. The accomplishments described in this annual report demonstrate the strong alignment of the LDRD portfolio with these missions and contribute to the Laboratory's success in meeting its goals. The LDRD budget of $91.5 million for fiscal yearmore » 2008 sponsored 176 projects. These projects were selected through an extensive peer-review process to ensure the highest scientific quality and mission relevance. Each year, the number of deserving proposals far exceeds the funding available, making the selection a tough one indeed. Our ongoing investments in LDRD have reaped long-term rewards for the Laboratory and the nation. Many Laboratory programs trace their roots to research thrusts that began several years ago under LDRD sponsorship. In addition, many LDRD projects contribute to more than one mission area, leveraging the Laboratory's multidisciplinary team approach to science and technology. Safeguarding the nation from terrorist activity and the proliferation of weapons of mass destruction will be an enduring mission of this Laboratory, for which LDRD will continue to play a vital role. The LDRD Program is a success story. Our projects continue to win national recognition for excellence through prestigious awards, papers published in peer-reviewed journals, and patents granted. With its reputation for sponsoring innovative projects, the LDRD Program is also a major vehicle for attracting and retaining the best and the brightest technical staff and for establishing collaborations with universities, industry, and other scientific and research institutions. By keeping the Laboratory at the forefront of science and technology, the LDRD Program enables us to meet our mission challenges, especially those of our ever-evolving national security mission. The Laboratory Directed Research and Development (LDRD) annual report for fiscal year 2008 (FY08) provides a summary of LDRD-funded projects for the fiscal year and consists of two parts: A broad description of the LDRD Program, the LDRD portfolio-management process, program statistics for the year, and highlights of accomplishments for the year. A summary of each project, submitted by the principal investigator. Project summaries include the scope, motivation, goals, relevance to Department of Energy (DOE)/National Nuclear Security Administration (NNSA) and Lawrence Livermore National Laboratory (LLNL) mission areas, the technical progress achieved in FY08, and a list of publications that resulted from the research in FY08. Summaries are organized in sections by research category (in alphabetical order). Within each research category, the projects are listed in order of their LDRD project category: Strategic Initiative (SI), Exploratory Research (ER), Laboratory-Wide Competition (LW), and Feasibility Study (FS). Within each project category, the individual project summaries appear in order of their project tracking code, a unique identifier that consists of three elements. The first is the fiscal year the project began, the second represents the project category, and the third identifies the serial number of the proposal for that fiscal year.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jacobs, R

The Physics and Advanced Technologies (PAT) Directorate was created in July 2000 by Bruce Tarter, Director of Lawrence Livermore National Laboratory (LLNL). The Director called for the new organization to execute and support programs that apply cutting-edge physics and advanced technology to develop integrated solutions to problems in national security, fusion energy, information science, health care, and other national grand challenges. When I was appointed a year later as the PAT Directorate's first Associate Director, I initiated a strategic planning project to develop a vision, mission, and long-term goals for the Directorate. We adopted the goal of becoming a leadermore » in frontier physics and technology for twenty-first-century national security missions: Stockpile Stewardship, homeland security, energy independence, and the exploration of space. Our mission is to: (1) Help ensure the scientific excellence and vitality of the major LLNL programs through its leadership role in performing basic and applied multidisciplinary research and development with programmatic impact, and by recruiting and retaining science and technology leaders; (2) Create future opportunities and directions for LLNL and its major programs by growing new program areas and cutting-edge capabilities that are synergistic with, and supportive of, its national security mission; (3) Provide a direct conduit to the academic and high-tech industrial sectors for LLNL and its national security programs, through which the Laboratory gains access to frontier science and technology, and can impact the science and technology communities; (4) Leverage unique Laboratory capabilities, to advance the state universe. This inaugural PAT Annual Report begins a series that will chronicle our progress towards fulfilling this mission. I believe the report demonstrates that the PAT Directorate has a strong base of capabilities and accomplishments on which to build in meeting its goals. Some of the highlights include: (1) Leadership of the Laboratory's Physical Data Research Program that provides fundamental physics information for the Stockpile Stewardship Program. (2) Development of the handheld Microbead Immunoassay Dipstick System that will allow relatively untrained first-responders to run sophisticated onsite diagnostics for pathogens, including those associated with biowarfare agents, by using a simple, one-step measurement. (3) Major advances in target design for inertial fusion energy research using both laser and ion-beam drivers. (4) Development of the Advanced Technology Kill Vehicle concept for use as a high-performance interceptor in a broad range of missile defense programs. Over the course of the past decade, the Laboratory has seen its major program evolve from weapons research, development, and testing, to Stockpile Stewardship. Today, the country's national security priorities are changing rapidly: nuclear security is becoming a broader set of missions, and the Laboratory is being asked to contribute to a range of new mission areas from countering bioterrorism to ensuring information security. As we embark on the twenty-first century, the new PAT Directorate is poised to help lead the Laboratory's response to the country's changing national security needs.« less

Fourth conference on radiation protection and dosimetry: Proceedings, program, and abstracts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Casson, W.H.; Thein, C.M.; Bogard, J.S.

This Conference is the fourth in a series of conferences organized by staff members of Oak Ridge National Laboratory in an effort to improve communication in the field of radiation protection and dosimetry. Scientists, regulators, managers, professionals, technologists, and vendors from the United States and countries around the world have taken advantage of this opportunity to meet with their contemporaries and peers in order to exchange information and ideas. The program includes over 100 papers in 9 sessions, plus an additional session for works in progress. Papers are presented in external dosimetry, internal dosimetry, radiation protection programs and assessments, developmentsmore » in instrumentation and materials, environmental and medical applications, and on topics related to standards, accreditation, and calibration. Individual papers are indexed separately on EDB.« less

Waste-Management Education and Research Consortium (WERC) annual progress report, 1992--1993. Appendices

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-02-15

This report contains the following appendices: Appendix A - Requirements for Undergraduate Level; Appendix B - Requirements for Graduate Level; Appendix C - Graduate Degree In Environmental Engineeringat New Mexico State University; Appendix D - Non-degree Certificate program; Appendix E - Curriculum for Associate Degree Program in Radioactive & Hazardous Waste Materials; Appendix F - Curriculum for NCC Program in Earth & Environmental Sciences; Appendix G - Brochure of 1992 Teleconference Series; Appendix H - Sites for Hazardous/Radioactive Waste Management Series; Appendix I - WERC Interactive Television Courses; Appendix J - WERC Research Seminar Series Brochures; Appendix K - Summarymore » of Technology Development of the Third Year; Appendix L - List of Major Publications Resulting From WERC; Appendix M - Types of Equipment at WERC Laboratories; and Appendix N - WERC Newsletter Examples.« less

Waste-Management Education and Research Consortium (WERC) annual progress report, 1992--1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eiceman, Gary A.; King, J. Phillip; Smith, Geoffrey B.

1993-02-15

This report contains the following appendices: Appendix A - Requirements for Undergraduate Level; Appendix B - Requirements for Graduate Level; Appendix C - Graduate Degree In Environmental Engineeringat New Mexico State University; Appendix D - Non-degree Certificate program; Appendix E - Curriculum for Associate Degree Program in Radioactive Hazardous Waste Materials; Appendix F - Curriculum for NCC Program in Earth Environmental Sciences; Appendix G - Brochure of 1992 Teleconference Series; Appendix H - Sites for Hazardous/Radioactive Waste Management Series; Appendix I - WERC Interactive Television Courses; Appendix J - WERC Research Seminar Series Brochures; Appendix K - Summary of Technologymore » Development of the Third Year; Appendix L - List of Major Publications Resulting From WERC; Appendix M - Types of Equipment at WERC Laboratories; and Appendix N - WERC Newsletter Examples.« less

Coding a Weather Model: DOE-FIU Science & Technology Workforce Development Program.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bradley, Jon David

DOE Fellow, Andres Cremisini, completed a 10-week internship with Sandia National Laboratories (SNL) in Albuquerque, New Mexico. Under the management of Kristopher Klingler and the mentorship of Jon Bradley, he was tasked with conceiving and coding a realistic weather model for use in physical security applications. The objective was to make a weather model that could use real data to accurately predict wind and precipitation conditions at any location of interest on the globe at any user-determined time. The intern received guidance on software design, the C++ programming language and clear communication of project goals and ongoing progress. In addition,more » Mr. Cremisini was given license to structure the program however he best saw fit, an experience that will benefit ongoing research endeavors.« less

A cost-effective approach to establishing a surgical skills laboratory.

PubMed

Berg, David A; Milner, Richard E; Fisher, Carol A; Goldberg, Amy J; Dempsey, Daniel T; Grewal, Harsh

2007-11-01

Recent studies comparing inexpensive low-fidelity box trainers to expensive computer-based virtual reality systems demonstrate similar acquisition of surgical skills and transferability to the clinical setting. With new mandates emerging that all surgical residency programs have access to a surgical skills laboratory, we describe our cost-effective approach to teaching basic and advanced open and laparoscopic skills utilizing inexpensive bench models, box trainers, and animate models. Open models (basic skills, bowel anastomosis, vascular anastomosis, trauma skills) and laparoscopic models (basic skills, cholecystectomy, Nissen fundoplication, suturing and knot tying, advanced in vivo skills) are constructed using a combination of materials found in our surgical research laboratories, retail stores, or donated by industry. Expired surgical materials are obtained from our hospital operating room and animal organs from food-processing plants. In vivo models are performed in an approved research facility. Operation, maintenance, and administration of the surgical skills laboratory are coordinated by a salaried manager, and instruction is the responsibility of all surgical faculty from our institution. Overall, the cost analyses of our initial startup costs and operational expenditures over a 3-year period revealed a progressive decrease in yearly cost per resident (2002-2003, $1,151; 2003-2004, $1,049; and 2004-2005, $982). Our approach to surgical skills education can serve as a template for any surgery program with limited financial resources.

Corridor One:An Integrated Distance Visualization Enuronments for SSI+ASCI Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Christopher R. Johnson, Charles D. Hansen

2001-10-29

The goal of Corridor One: An Integrated Distance Visualization Environment for ASCI and SSI Application was to combine the forces of six leading edge laboratories working in the areas of visualization and distributed computing and high performance networking (Argonne National Laboratory, Lawrence Berkeley National Laboratory, Los Alamos National Laboratory, University of Illinois, University of Utah and Princeton University) to develop and deploy the most advanced integrated distance visualization environment for large-scale scientific visualization and demonstrate it on applications relevant to the DOE SSI and ASCI programs. The Corridor One team brought world class expertise in parallel rendering, deep image basedmore » rendering, immersive environment technology, large-format multi-projector wall based displays, volume and surface visualization algorithms, collaboration tools and streaming media technology, network protocols for image transmission, high-performance networking, quality of service technology and distributed computing middleware. Our strategy was to build on the very successful teams that produced the I-WAY, ''Computational Grids'' and CAVE technology and to add these to the teams that have developed the fastest parallel visualizations systems and the most widely used networking infrastructure for multicast and distributed media. Unfortunately, just as we were getting going on the Corridor One project, DOE cut the program after the first year. As such, our final report consists of our progress during year one of the grant.« less

New Brunswick Laboratory. Progress report, October 1995--September 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

Fiscal year (FY) 1996 was a very good year for New Brunswick Laboratory (NBL), whose major sponsor is the Office of Safeguards and Security (NN-51) in the US Department of Energy (DOE), Office of Nonproliferation and National Security, Office of Security Affairs. Several projects pertinent to the NBL mission were completed, and NBL`s interactions with partners and customers were encouraging. Among the partners with which NBL interacted in this report period were the International Atomic Energy Agency (IAEA), NN-51. Environmental Program Group of the DOE Chicago Operations Office, International Safeguards Project Office, Waste Isolation Pilot Plant (WIPP), Ukraine Working Group,more » Fissile Materials Assurance Working Group, National Institute of Standards and Technology (NIST), Nuclear Regulatory Commission (NRC), Institute for Reference Materials and Measurements (IRMM) in Belgium, Brazilian/Argentine Agency for Accounting and Control of Nuclear Materials (ABACC), Lockheed Idaho Technologies Company, and other DOE facilities and laboratories. NBL staff publications, participation in safeguards assistance and other nuclear programs, development of new reference materials, involvement in the updating and refinement of DOE documents, service in enhancing the science education of others, and other related activities enhanced NBL`s status among DOE laboratories and facilities. Noteworthy are the facts that NBL`s small inventory of nuclear materials is accurately accounted for, and, as in past years, its materials and human resources were used in peaceful nuclear activities worldwide.« less

Waste Isolation Pilot Plant Materials Interface Interactions Test: Papers presented at the Commission of European Communities workshop on in situ testing of radioactive waste forms and engineered barriers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Molecke, M.A.; Sorensen, N.R.; Wicks, G.G.

The three papers in this report were presented at the second international workshop to feature the Waste Isolation Pilot Plant (WIPP) Materials Interface Interactions Test (MIIT). This Workshop on In Situ Tests on Radioactive Waste Forms and Engineered Barriers was held in Corsendonk, Belgium, on October 13--16, 1992, and was sponsored by the Commission of the European Communities (CEC). The Studiecentrum voor Kernenergie/Centre D`Energie Nucleaire (SCK/CEN, Belgium), and the US Department of Energy (via Savannah River) also cosponsored this workshop. Workshop participants from Belgium, France, Germany, Sweden, and the United States gathered to discuss the status, results and overviews ofmore » the MIIT program. Nine of the twenty-five total workshop papers were presented on the status and results from the WIPP MIIT program after the five-year in situ conclusion of the program. The total number of published MIIT papers is now up to almost forty. Posttest laboratory analyses are still in progress at multiple participating laboratories. The first MIIT paper in this document, by Wicks and Molecke, provides an overview of the entire test program and focuses on the waste form samples. The second paper, by Molecke and Wicks, concentrates on technical details and repository relevant observations on the in situ conduct, sampling, and termination operations of the MIIT. The third paper, by Sorensen and Molecke, presents and summarizes the available laboratory, posttest corrosion data and results for all of the candidate waste container or overpack metal specimens included in the MIIT program.« less

Advanced Simulation and Computing: A Summary Report to the Director's Review

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCoy, M G; Peck, T

2003-06-01

It has now been three years since the Advanced Simulation and Computing Program (ASCI), as managed by Defense and Nuclear Technologies (DNT) Directorate, has been reviewed by this Director's Review Committee (DRC). Since that time, there has been considerable progress for all components of the ASCI Program, and these developments will be highlighted in this document and in the presentations planned for June 9 and 10, 2003. There have also been some name changes. Today, the Program is called ''Advanced Simulation and Computing,'' Although it retains the familiar acronym ASCI, the initiative nature of the effort has given way tomore » sustained services as an integral part of the Stockpile Stewardship Program (SSP). All computing efforts at LLNL and the other two Defense Program (DP) laboratories are funded and managed under ASCI. This includes the so-called legacy codes, which remain essential tools in stockpile stewardship. The contract between the Department of Energy (DOE) and the University of California (UC) specifies an independent appraisal of Directorate technical work and programmatic management. Such represents the work of this DNT Review Committee. Beginning this year, the Laboratory is implementing a new review system. This process was negotiated between UC, the National Nuclear Security Administration (NNSA), and the Laboratory Directors. Central to this approach are eight performance objectives that focus on key programmatic and administrative goals. Associated with each of these objectives are a number of performance measures to more clearly characterize the attainment of the objectives. Each performance measure has a lead directorate and one or more contributing directorates. Each measure has an evaluation plan and has identified expected documentation to be included in the ''Assessment File''.« less

Biology Division progress report for period of October 1, 1988--September 30, 1989

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1990-02-01

The Biology Division of the Oak Ridge National Laboratory is one component of the Department of Energy's intramural program in life sciences. With respect to experimental biology, the congressionally mandated mission of this Office is to study adverse health effects of energy production and utilization. Within this stated broad mission, common themes among the research programs of the Biology Division are interactions of animals, cells, and molecules with their respective environments. Investigations focus on genetic and somatic effects of radiation and chemicals. Goals include identification and quantification of these effects, elucidation of pathways by which the effects are expressed, assessmentmore » of risks associated with radiation and chemical exposures, and establishment of strategies for extrapolation of risk data from animals to humans. Concurrent basic studies in genetics, biochemistry, molecular biology, and cell biology illuminate normal life processes as prerequisites to comprehending mutagenic and carcinogenic effects of environmental agents. This Progress Report is intended to provide both broad perspectives of the Division's research programs and synopses of recent achievements. Readers are invited to contact individual principal investigators for more detailed information, including reprints of publications. 120 refs.« less

Uranium hydrogeochemical and stream sediment reconnaissance of the Solomon NTMS quadrangle, Alaska

DOE Office of Scientific and Technical Information (OSTI.GOV)

Langfeldt, S.L.; Youngquist, C.A.; D'Andrea, R.F. Jr.

This report presents results of a Hydrogeochemical and Stream Sediment Reconnaissance (HSSR) of the Solomon NTMS quadrangle, Alaska. In addition to this abbreviated data release, more complete data are available to the public in machine-readable form through the Grand Junction Office Information System at Oak Ridge National Laboratory. Presented in this data release are location data, field analyses, and laboratory analyses of several different sample media. For the sake of brevity, many field site observations have not been included in this volume. These data are, however, available on the magnetic tape. Appendices A and B describe the sample media andmore » summarize the analytical results for each medium. The data were subdivided by one of the Los Alamos National Laboratory (LANL) sorting programs of Zinkl and others into groups of stream sediment and stream water samples. For each group which contains a sufficient number of observations, statistical tables, tables of raw data, and 1:1000000 scale maps of pertinent elements have been included in this report. In addition, maps showing results of multivariate statistical analyses have been included. Further information about the HSSR program in general, or about the LANL portion of the program in particular, can be obtained in quarterly or semiannual program progress reports on open-file at DOE's Technical Library in Grand Junction. Information about the field and analytical procedures used by LANL during sample collection and analysis may be found in any HSSR data release prepared by the LANL and will not be included in this report.« less

Edge Simulation Laboratory Progress and Plans

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cohen, R

The Edge Simulation Laboratory (ESL) is a project to develop a gyrokinetic code for MFE edge plasmas based on continuum (Eulerian) techniques. ESL is a base-program activity of OFES, with an allied algorithm research activity funded by the OASCR base math program. ESL OFES funds directly support about 0.8 FTE of career staff at LLNL, a postdoc and a small fraction of an FTE at GA, and a graduate student at UCSD. In addition the allied OASCR program funds about 1/2 FTE each in the computations directorates at LBNL and LLNL. OFES ESL funding for LLNL and UCSD began inmore » fall 2005, while funding for GA and the math team began about a year ago. ESL's continuum approach is a complement to the PIC-based methods of the CPES Project, and was selected (1) because of concerns about noise issues associated with PIC in the high-density-contrast environment of the edge pedestal, (2) to be able to exploit advanced numerical methods developed for fluid codes, and (3) to build upon the successes of core continuum gyrokinetic codes such as GYRO, GS2 and GENE. The ESL project presently has three components: TEMPEST, a full-f, full-geometry (single-null divertor, or arbitrary-shape closed flux surfaces) code in E, {mu} (energy, magnetic-moment) coordinates; EGK, a simple-geometry rapid-prototype code, presently of; and the math component, which is developing and implementing algorithms for a next-generation code. Progress would be accelerated if we could find funding for a fourth, computer science, component, which would develop software infrastructure, provide user support, and address needs for data handing and analysis. We summarize the status and plans for the three funded activities.« less

Introducing Deep Underground Science to Middle Schoolers: Challenges and Rewards

NASA Astrophysics Data System (ADS)

McMahan Norris, Margaret

2010-03-01

Work is in progress to define the mission, vision, scope and preliminary design of the Sanford Center for Science Education (SCSE), the education arm of the Deep Underground Science and Engineering Laboratory (DUSEL), a proposed major research facility of the National Science Foundation. If final funding is approved, DUSEL will be built at the site of the former Homestake Gold Mine in Lead, South Dakota beginning in 2012. The SCSE is envisioned to serve as a model for the integration of a science education center into the fabric of a new national laboratory. Its broad mission is to share the excitement and promise of deep underground science and engineering at Homestake with learners of all ages worldwide. The science to be pursued at DUSEL, whether in physics, astronomy, geomicrobiology, or geoscience, is transformational and sparks the imagination of learners of all ages. While the SCSE is under design, an early education program has been initiated that is designed to build capacity for the envisioned center, to prototype individual programs, and to build partnerships and community support. This talk will give an overview of the middle school portion of that program and its context within the overall content development plan of the SCSE.

Tiger Team assessment of the Lawrence Berkeley Laboratory, Washington, DC

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-02-01

This report documents the results of the Department of Energy's (DOE's) Tiger Team Assessment of the Lawrence Berkeley Laboratory (LBL) conducted from January 14 through February 15, 1991. The purpose of the assessment was to provide the Secretary of Energy with the status of environment, safety, and health (ES H) programs at LBL. The Tiger Team concluded that curtailment of cessation of any operations at LBL is not warranted. However, the number and breadth of findings and concerns from this assessment reflect a serious condition at this site. In spite of its late start, LBL has recently made progress inmore » increasing ES H awareness at all staff levels and in identifying ES H deficiencies. Corrective action plans are inadequate, however, many compensatory actions are underway. Also, LBL does not have the technical expertise or training programs nor the tracking and followup to effectively direct and control sitewide guidance and oversight by DOE of ES H activities at LBL. As a result of these deficiencies, the Tiger Team has reservations about LBL's ability to implement effective actions in a timely manner and, thereby, achieve excellence in their ES H program. 4 figs., 24 tabs.« less

Bone Conduction Communication: Research Progress and Directions

DTIC Science & Technology

2017-08-16

ARL-TR-8096 ● AUG 2017 US Army Research Laboratory Bone Conduction Communication: Research Progress and Directions by Maranda...this report when it is no longer needed. Do not return it to the originator. ARL-TR-8096 ● AUG 2017 US Army Research Laboratory...Bone Conduction Communication: Research Progress and Directions by Maranda McBride North Carolina Agricultural and Technical State University

Fusion energy division annual progress report, period ending December 31, 1980

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1981-11-01

The ORNL Program encompasses most aspects of magnetic fusion research including research on two magnetic confinement programs (tokamaks and ELMO bumpy tori); the development of the essential technologies for plasma heating, fueling, superconducting magnets, and materials; the development of diagnostics; the development of atomic physics and radiation effect data bases; the assessment of the environmental impact of magnetic fusion; the physics and engineering of present-generation devices; and the design of future devices. The integration of all of these activities into one program is a major factor in the success of each activity. An excellent example of this integration is themore » extremely successful application of neutral injection heating systems developed at ORNL to tokamaks both in the Fusion Energy Division and at Princeton Plasma Physics Laboratory (PPPL). The goal of the ORNL Fusion Program is to maintain this balance between plasma confinement, technology, and engineering activities.« less

Photovoltaic Subcontract Program. Annual report, FY 1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-03-01

This report summarizes the fiscal year (FY) 1992 progress of the subcontracted photovoltaic (PV) research and development (R&D) performed under the Photovoltaic Advanced Research and Development Project at the National Renewable Energy Laboratory (NREL)-formerly the Solar Energy Research Institute (SERI). The mission of the national PV program is to develop PV technology for large-scale generation of economically competitive electric power in the United States. The technical sections of the report cover the main areas of the subcontract program: the Crystalline Materials and Advanced Concepts project, the Polycrystalline Thin Films project, Amorphous Silicon Research project, the Photovoltaic Manufacturing Technology (PVMaT) project,more » PV Module and System Performance and Engineering project, and the PV Analysis and Applications Development project. Technical summaries of each of the subcontracted programs provide a discussion of approaches, major accomplishments in FY 1992, and future research directions.« less

RAWP Progress Report August 19, 2011 - Combined

EPA Pesticide Factsheets

Combines cover letter and Progress Report #2 as required in Residential Soil Remedial Action Work Plan (RAWP)-Phase 1, with the Analytical Laboratory Report of Walter Coke Inc site in Birmingham AL, August 16, 2011, prepared by TestAmerica Laboratories.

Final Progress Report for Award DE-FG07-05ID14637.pdf

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cathy Dixon

2012-03-09

2004-2011 Final Report for AFCI University Fellowship Program. The goal of this effort was to be supportive of university students and university programs - particularly those students and programs that will help to strengthen the development of nuclear-related fields. The program also supported the stability of the nuclear infrastructure and developed research partnerships that are helping to enlarge the national nuclear science technology base. In this fellowship program, the U.S. Department of Energy sought master's degree students in nuclear, mechanical, or chemical engineering, engineering/applied physics, physics, chemistry, radiochemistry, or fields of science and engineering applicable to the AFCI/Gen IV/GNEP missionsmore » in order to meet future U.S. nuclear program needs. The fellowship program identified candidates and selected full time students of high-caliber who were taking nuclear courses as part of their degree programs. The DOE Academic Program Managers encouraged fellows to pursue summer internships at national laboratories and supported the students with appropriate information so that both the fellows and the nation's nuclear energy objectives were successful.« less

FY04 Engineering Technology Reports Technology Base

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sharpe, R M

2005-01-27

Lawrence Livermore National Laboratory's Engineering Directorate has two primary discretionary avenues for its investment in technologies: the Laboratory Directed Research and Development (LDRD) program and the ''Tech Base'' program. This volume summarizes progress on the projects funded for technology-base efforts in FY2004. The Engineering Technical Reports exemplify Engineering's more than 50-year history of researching and developing (LDRD), and reducing to practice (technology-base) the engineering technologies needed to support the Laboratory's missions. Engineering has been a partner in every major program and project at the Laboratory throughout its existence, and has prepared for this role with a skilled workforce and technicalmore » resources. This accomplishment is well summarized by Engineering's mission: ''Enable program success today and ensure the Laboratory's vitality tomorrow''. LDRD is the vehicle for creating those technologies and competencies that are cutting edge. These require a significant level of research or contain some unknown that needs to be fully understood. Tech Base is used to apply those technologies, or adapt them to a Laboratory need. The term commonly used for Tech Base projects is ''reduction to practice''. Tech Base projects effect the natural transition to reduction-to-practice of scientific or engineering methods that are well understood and established. They represent discipline-oriented, core competency activities that are multi-programmatic in application, nature, and scope. The objectives of technology-base funding include: (1) the development and enhancement of tools and processes to provide Engineering support capability, such as code maintenance and improved fabrication methods; (2) support of Engineering science and technology infrastructure, such as the installation or integration of a new capability; (3) support for technical and administrative leadership through our technology Centers; and (4) the initial scoping and exploration of selected technology areas with high strategic potential, such as assessment of university, laboratory, and industrial partnerships. Engineering's five Centers, in partnership with the Division Leaders and Department Heads, focus and guide longer-term investments within Engineering. The Centers attract and retain top staff, develop and maintain critical core technologies, and enable programs. Through their technology-base projects, they oversee the application of known engineering approaches and techniques to scientific and technical problems. The Centers and their Directors are as follows: (1) Center for Computational Engineering: Robert M. Sharpe; (2) Center for Microtechnology and Nanotechnology: Raymond P. Mariella, Jr. (3) Center for Nondestructive Characterization: Harry E. Martz, Jr.; (4) Center for Precision Engineering: Keith Carlisle; and (5) Center for Complex Distributed Systems: Gregory J. Suski, Acting Director.« less

Ionospheric chemistry. [minor neutrals and ionized constituents of thermosphere

NASA Technical Reports Server (NTRS)

Torr, D. G.

1979-01-01

This report deals primarily with progress in the chemistry of minor neutrals and ionized constituents of the thermosphere. Significant progress was made over the last few years in quantitative studies of many chemical processes. This success was primarily due to the advent of multiparameter multisatellite programs which permitted accurate simultaneous measurements to be made of many important parameters. In many cases studies of chemical reactions were made with laboratory-like precision. Rate coefficients have been derived as functions of temperature for a number of important reactions. New information has been acquired on nearly every major process which occurs in the thermosphere, including the recombination rates of all major molecular ions, charge transfer reactions, ion atom interchange reactions, and reactions of neutral and ionized metastable atoms and molecules.

Chemistry Division. Quarterly progress report for period ending June 30, 1949

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1949-09-14

Progress reports are presented for the following tasks: (1) nuclear and chemical properties of heavy elements (solution chemistry, phase rule studies); (2) nuclear and chemical properties of elements in the fission product region; (3) general nuclear chemistry; (4) radio-organic chemistry; (5) chemistry of separations processes; (6) physical chemistry and chemical physics; (7) radiation chemistry; (8) physical measurements and instrumentation; and (9) analytical chemistry. The program of the chemistry division is divided into two efforts of approximately equal weight with respect to number of personnel, chemical research, and analytical service for the Laboratory. The various research problems fall into the followingmore » classifications: (1) chemical separation processes for isolation and recovery of fissionable material, production of radioisotopes, and military applications; (2) reactor development; and (3) fundamental research.« less

Biology Division. Progress report, August 1, 1982-September 30, 1983

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1984-01-01

The Biology Division is the component of the Oak Ridge National Laboratory that investigates the potential adverse health effects of energy-related substances. The body of this report provides summaries of the aims, scope and progress of the research of groups of investigators in the Division during the period of August 1, 1982, through September 30, 1983. At the end of each summary is a list of publications covering the same period (published or accepted for publication). For convenience, the summaries are assembled under Sections in accordance with the current organizational structure of the Biology Division; each Section begins with anmore » overview. It will be apparent, however, that currents run throughout the Division and that the various programs support and interact with each other.« less

Biotechnology by Design: An Introductory Level, Project-Based, Synthetic Biology Laboratory Program for Undergraduate Students†

PubMed Central

Beach, Dale L.; Alvarez, Consuelo J.

2015-01-01

Synthetic biology offers an ideal opportunity to promote undergraduate laboratory courses with research-style projects, immersing students in an inquiry-based program that enhances the experience of the scientific process. We designed a semester-long, project-based laboratory curriculum using synthetic biology principles to develop a novel sensory device. Students develop subject matter knowledge of molecular genetics and practical skills relevant to molecular biology, recombinant DNA techniques, and information literacy. During the spring semesters of 2014 and 2015, the Synthetic Biology Laboratory Project was delivered to sophomore genetics courses. Using a cloning strategy based on standardized BioBrick genetic “parts,” students construct a “reporter plasmid” expressing a reporter gene (GFP) controlled by a hybrid promoter regulated by the lac-repressor protein (lacI). In combination with a “sensor plasmid,” the production of the reporter phenotype is inhibited in the presence of a target environmental agent, arabinose. When arabinose is absent, constitutive GFP expression makes cells glow green. But the presence of arabinose activates a second promoter (pBAD) to produce a lac-repressor protein that will inhibit GFP production. Student learning was assessed relative to five learning objectives, using a student survey administered at the beginning (pre-survey) and end (post-survey) of the course, and an additional 15 open-ended questions from five graded Progress Report assignments collected throughout the course. Students demonstrated significant learning gains (p < 0.05) for all learning outcomes. Ninety percent of students indicated that the Synthetic Biology Laboratory Project enhanced their understanding of molecular genetics. The laboratory project is highly adaptable for both introductory and advanced courses. PMID:26753032

Reproducibility of cervical cytopathology following an intervention by an external quality control laboratory.

PubMed

Ázara, Cinara Zago Silveira; Manrique, Edna Joana Claudio; Tavares, Suelene Brito do Nascimento; Alves de Souza, Nadja Lindany; Magalhães, Juliana Cristina; Amaral, Rita Goreti

2016-04-01

This study assessed the effects of a continued education program on the agreement between cervical cytopathology exams interpreted by local laboratories and interpretation made by an external quality control laboratory (LabMEQ). Overall, 9,798 exams were analyzed between 2007 and 2008, prior to implementation of a continued education program, and 10,028 between 2010 and 2011, following implementation. Continued education consisted of theoretical and practical classes held every two months. The chi-square test and the kappa coefficient were used in the statistical analysis. Following implementation of continued education, the rate of false-negative results, and those leading to delays in clinical management fell in eight laboratories and the rate of false-positive results in five. Agreement between the results reported by the laboratories and the findings of LabMEQ, evaluated according to clinical management, remained excellent in three laboratories (kappa >0.80 and <1.0), went from good (kappa >0.60 and <0.80) to excellent in seven and from excellent to good in two. Agreement regarding the identification of metaplastic epithelium was poor (kappa = 0.25) but progressed to excellent following the implementation of continued education (kappa = 0.950). Agreement between cytopathology results improved significantly following implementation of continued education in cases reported as unsatisfactory (P < 0.001), atypical squamous cells of undetermined significance, cannot exclude high-grade squamous intraepithelial lesion (P < 0.001), low-grade squamous intraepithelial lesion (P < 0.001), and glandular atypia (P < 0.001). Continued education contributed towards improving the reproducibility of cervical cytopathology, decreased the rates of false-negative and false-positive results, and reduced delays in clinical management. © 2016 Wiley Periodicals, Inc.

PREFACE: The fifth International Conference on Inertial Fusion Sciences and Applications (IFSA2007)

NASA Astrophysics Data System (ADS)

Azechi, Hiroshi; Hammel, Bruce; Gauthier, Jean-Claude

2008-06-01

The Fifth International Conference on Inertial Fusion Sciences and Applications (IFSA 2007) was held on 9-14 September 2007 at Kobe International Conference Center in Kobe, Japan. The host organizations for this conference were Osaka University and the Institute of Laser Engineering (ILE) at Osaka University; and co-organized by the Institute Lasers and Plasmas (ILP) in France, the Commissariatá l'Energie Atomique (CEA), Lawrence Livermore National Laboratory (LLNL), National Institute for Fusion Science (NIFS) in Japan, and Kansai Photon Science Institute (KPSI), Japan Atomic Energy Agency (JAEA). The conference objective was to review the state of the art of research in inertial fusion sciences and applications since the last conference held in Biarritz, France, in 2005. 470 abstracts were accepted, and 448 persons from 18 countries attended the conference. These Proceedings contain 287 of the papers presented at IFSA 2007. This collection of papers represents the manuscripts submitted to and passing the peer review process. The program was organized with some specific features: The reviews of influential programs appeared both at the very beginning and at the very end of the Conference to attract attendance throughout the Conference. Each poster session had the same time period as a single oral session, thereby avoiding overlap with oral talks. The everyday program was structured to be as similar as possible so the attendees could easily recognize the program. With a goal of achieving inertial fusion ignition and burn propagation in the laboratory, researchers presented the exciting advances in both traditional hot spot ignition and fast ignition approach, including status report of USA's National Ignition Facility (NIF), French Laser Magajoule (LMJ), Japanese Fast Ignition Realization Experiment (FIREX), and European High Power laser Energy Research (HiPER). A particular emphasis of the meeting was that the `physics of inertial fusion' category was dominated by fast-ignition and related ultra-intense laser interaction. Progress in direct drive over the past few years resulted in the achievement of high-density cryogenic implosions at OMEGA. Continuous progresses in hohlraum physics gave confidence in the achievement of ignition at NIF and LMJ. Advances in Z-pinch included double-hohlraum irradiation symmetry and the PW laser beam for the Z-facility. Progress of laser material development for IFE driver was a very interesting topic of inertial fusion energy drivers, including KrF and DPSSL lasers and particle beams. Of special interest, a future session was focused on strategy of inertial fusion energy development. Laboratory tours were held in the middle of the Conference. The Laser for Fusion EXperiments (LFEX), a new high-energy petawatt laser at ILE, was one of the key attractions of IFSA 2007. 83 participants toured LFEX and GEKKO XII lasers, and 35 joined a tour of KPSA-JAEA. In parallel to the tour, the `Symposium on Academics-Industries Cooperation for Applications of High-Power Lasers' was held with more than 90 participants mostly from the industrial community. These Proceedings start with special chapters on the keynote and focus speeches and the Teller lectures. The keynotes and focus give an overview of progress in inertial fusion in Asia, North America, and Europe. The Teller lectures show the contributions of this year's two winners: Brian Thomas of AWE, UK and Kunioki Mima of ILE. The remainder of the Proceedings is divided into three parts. Part A covers the physics of inertial fusion; Part B covers laser, particle beams, and fusion technology including IFE reactors and target fabrication; and Part C covers science and technology applications such as laboratory astrophysics, laser particle acceleration, x-ray and EUV sources, and new applications of intense lasers. These parts are further divided into chapters covering specific areas of science or technology. Within each chapter the talks relevant to that subject are gathered. The IFSA International Organizing Committee and Scientific Advisory Board appreciate the efforts of inertial fusion researchers worldwide in making IFSA 2007 an extremely successful conference. The proceedings were published with the support of Dr Y Sakawa, Dr H Homma, Ms S Karasuyama, Ms M Odagiri, and Ms I Kobatake. Kunioki Mima Co-chair Hiroshi Azechi Technical Program Committee Co-chair John Lindl Co-chair Bruce Hammel Technical Program Committee Co-chair Christine Labaune Co-chair Jean-Claude Gauthier Technical Program Committee Co-chair

AERIAL VIEW OF MAIN PROCESSING BUILDING SHOWING CONSTRUCTION PROGRESS AND ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

AERIAL VIEW OF MAIN PROCESSING BUILDING SHOWING CONSTRUCTION PROGRESS AND EXCAVATION FOR LABORATORY ON LEFT. INL PHOTO NUMBER NRTS-51-1759. Unknown Photographer, 3/28/1951 - Idaho National Engineering Laboratory, Idaho Chemical Processing Plant, Fuel Reprocessing Complex, Scoville, Butte County, ID

Cell cycle behavior of laboratory and field populations of the Florida red tide dinoflagellate, Karenia brevis

NASA Astrophysics Data System (ADS)

Van Dolah, Frances M.; Leighfield, Tod A.; Kamykowski, Daniel; Kirkpatrick, Gary J.

2008-01-01

As a component of the ECOHAB Florida Regional Field Program, this study addresses cell cycle behavior and its importance to bloom formation of the Florida red tide dinoflagellate, Karenia brevis. The cell cycle of K. brevis was first studied by flow cytometry in laboratory batch cultures, and a laboratory mesocosm column, followed by field populations over the 5-year course of the ECOHAB program. Under all conditions studied, K. brevis displayed diel phased cell division with S-phase beginning a minimum of 6 h after the onset of light and continuing for 12-14 h. Mitosis occurred during the dark, and was generally completed by the start of the next day. The timing of cell cycle phases relative to the diel cycle did not differ substantially in bloom populations displaying radically different growth rates ( μmin 0.17-0.55) under different day lengths and temperature conditions. The rhythm of cell cycle progression is independent from the rhythm controlling vertical migration, as similar cell cycle distributions are found at all depths of the water column in field samples. The implications of these findings are discussed in light of our current understanding of the dinoflagellate cell cycle and the development of improved models for K. brevis bloom growth.

The U.S. Earthquake Prediction Program

USGS Publications Warehouse

Wesson, R.L.; Filson, J.R.

1981-01-01

There are two distinct motivations for earthquake prediction. The mechanistic approach aims to understand the processes leading to a large earthquake. The empirical approach is governed by the immediate need to protect lives and property. With our current lack of knowledge about the earthquake process, future progress cannot be made without gathering a large body of measurements. These are required not only for the empirical prediction of earthquakes, but also for the testing and development of hypotheses that further our understanding of the processes at work. The earthquake prediction program is basically a program of scientific inquiry, but one which is motivated by social, political, economic, and scientific reasons. It is a pursuit that cannot rely on empirical observations alone nor can it carried out solely on a blackboard or in a laboratory. Experiments must be carried out in the real Earth. 

Advanced Industrial Materials (AIM) program. Annual progress report. FY 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-04-01

The Advanced Industrial Materials (AIM) Program underwent a major transformation in Fiscal Year 1995 and these changes have continued to the present. When the Program was established in 1990 as the Advanced Industrial Concepts (AIC) Materials Program, the mission was to conduct applied research and development to bring materials and processing technologies from the knowledge derived from basic research to the maturity required for the end use sectors for commercialization. In 1995, the Office of Industrial Technologies (OIT) made radical changes in structure and procedures. All technology development was directed toward the seven `Vision Industries` that use about 80% ofmore » industrial energy and generated about 90% of industrial wastes. These are: aluminium; chemical; forest products; glass; metal casting; refineries; and steel. OIT is working with these industries, through appropriate organizations, to develop Visions of the desired condition of each industry some 20 or 25 years in the future and then to prepare Road Maps and Implementation Plans to enable them to reach their goals. The mission of AIM has, therefore, changed to `Support development and commercialization of new or improved materials to improve productivity, product quality, and energy efficiency in the major process industries.` Though AIM remains essentially a National Laboratory Program, it is necessary that each project have industrial partners, including suppliers to, and customers of, the seven industries. Now, well into FY 1996, the transition is nearly complete and the AIM Program remains healthy and productive, thanks to the superb investigators and Laboratory Program Managers. Separate abstracts have been indexed into the energy database for articles from this report.« less

Active Control of Aerodynamic Noise Sources

NASA Technical Reports Server (NTRS)

Reynolds, Gregory A.

2001-01-01

Aerodynamic noise sources become important when propulsion noise is relatively low, as during aircraft landing. Under these conditions, aerodynamic noise from high-lift systems can be significant. The research program and accomplishments described here are directed toward reduction of this aerodynamic noise. Progress toward this objective include correction of flow quality in the Low Turbulence Water Channel flow facility, development of a test model and traversing mechanism, and improvement of the data acquisition and flow visualization capabilities in the Aero. & Fluid Dynamics Laboratory. These developments are described in this report.

New laboratory measurements on ammonia's inversion spectrum, with implications for planetary atmospheres

NASA Technical Reports Server (NTRS)

Spilker, Thomas R.

1993-01-01

Microwave spectral measurements have been performed on pure room-temperature gaseous ammonia at frequencies from 1.75 to 18 GHz (1.7-17 cm), at 50-, 100-, and 300-torr pressures. These measurements are part of a laboratory program to measure the microwave absorption spectrum of ammonia, under conditions applicable to giant planet atmospheres, now in progress at the Jet Propulsion Laboratory. The pure ammonia data reported here agree well with previous data by Bleaney and Loubser (1950) at 100 and 300 torrs, and with predictions of the absorptivity formalism published by Berge and Gulkis. Success with pure ammonia but failure with mixtures of ammonia in hydrogen and helium (Spilker, 1990) indicates that the Berge and Gulkis formalism does not correctly handle foreign-gas effects on ammonia inversion lines. This may require modifying conclusions of radio astronomical and radio occultation studies that used this formalism. Notably, a suggested depletion of ammonia and superabundance of hydrogen sulfide may have been exaggerated as a result of inaccuracies in the Berge and Gulkis formalism.

The NASA-Lewis/ERDA Solar Heating and Cooling Technology Program

NASA Technical Reports Server (NTRS)

Couch, J. P.; Bloomfield, H. S.

1975-01-01

The NASA Lewis Research Center plans to carry out a major role in the ERDA Solar Heating and Cooling Program. This role would be to create and test the enabling technology for future solar heating, cooling, and combined heating/cooling systems. The major objectives of the project are to achieve reduction in solar energy system costs, while maintaining adequate performance, reliability, life, and maintenance characteristics. The project approach is to move progressively through component, subsystem, and then system technology advancement phases in parallel with continuing manufacturing cost assessment studies. This approach will be accomplished principally by contract with industry to develop advanced components and subsystems. This advanced hardware will be tested to establish 'technology readiness' both under controlled laboratory conditions and under real sun conditions.

Performance evaluation of advanced battery technologies for electric vehicle applications

NASA Astrophysics Data System (ADS)

Deluca, W. H.; Tummillo, A. F.; Kulaga, J. E.; Webster, C. E.; Gillie, K. R.; Hogrefe, R. L.

1990-01-01

At the Argonne Analysis and Diagnostic Laboratory, advanced battery technology evaluations are performed under simulated electric vehicle operating conditions. During 1989 and the first quarter of 1990, single cell and multicell modules from seven developers were examined for the Department of Energy and Electric Power Research Institute. The results provide battery users, developers, and program managers with an interim measure of the progress being made in battery R&D programs, a comparison of battery technologies, and a source of basic data for modeling and continuing R&D. This paper summarizes the performance and life characterizations of two single cells and seven 3- to 960-cell modules that encompass six technologies (Na/S, Ni/Fe, Ni/Cd, Ni-metal hydride, lead-acid, and Zn/Br).

Survey of 2014 behavioral management programs for laboratory primates in the United States.

PubMed

Baker, Kate C

2016-07-01

The behavioral management of laboratory nonhuman primates in the United States has not been thoroughly characterized since 2003. This article presents the results of a survey behavioral management programs at 27 facilities and covering a total of 59,636 primates, 27,916 housed in indoor cages and 31,720 in group enclosures. The survey included questions regarding program structure, implementation, and methodology associated with social housing, positive reinforcement training, positive human interaction, exercise enclosures, and several categories of inanimate enrichment. The vast majority of laboratory primates are housed socially (83%). Since 2003, the proportion of indoor-housed primates reported to be housed singly has fallen considerably, from 59% to 35% in the facilities surveyed. The use of social housing remains significantly constrained by: 1) research protocol requirements, highlighting the value of closely involved IACUCs for harmonizing research and behavioral management; and 2) the unavailability of compatible social partners, underscoring the necessity of objective analysis of the methods used to foster and maintain compatibility. Positive reinforcement training appears to have expanded and is now used at all facilities responding to the survey. The use of enrichment devices has also increased in the participating facilities. For most behavioral management techniques, concerns over the possibility of negative consequences to animals are expressed most frequently for social housing and destructible enrichment, while skepticism regarding efficacy is limited almost exclusively to sensory enrichment. Behavioral management program staffing has expanded over time in the facilities surveyed, due not only to increased numbers of dedicated behavioral management technicians but also to greater involvement of animal care technicians, suggesting an increase in the integration of behavioral care into animal husbandry. Broad awareness of common practice may assist facilities with program evaluation and assessment of progress in the field can generate recommendations for continuing the advancement of primate behavioral management programs. Am. J. Primatol. 78:780-796, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Survey of 2014 Behavioral Management Programs for Laboratory Primates in the United States

PubMed Central

BAKER, KATE C.

2016-01-01

The behavioral management of laboratory nonhuman primates in the United States has not been thoroughly characterized since 2003. This article presents the results of a survey behavioral management programs at 27 facilities and covering a total of 59,636 primates, 27,916 housed in indoor cages and 31,720 in group enclosures. The survey included questions regarding program structure, implementation, and methodology associated with social housing, positive reinforcement training, positive human interaction, exercise enclosures, and several categories of inanimate enrichment. The vast majority of laboratory primates are housed socially (83%). Since 2003, the proportion of indoor-housed primates reported to be housed singly has fallen considerably, from 59% to 35% in the facilities surveyed. The use of social housing remains significantly constrained by: 1) research protocol requirements, highlighting the value of closely involved IACUCs for harmonizing research and behavioral management; and 2) the unavailability of compatible social partners, underscoring the necessity of objective analysis of the methods used to foster and maintain compatibility. Positive reinforcement training appears to have expanded and is now used at all facilities responding to the survey. The use of enrichment devices has also increased in the participating facilities. For most behavioral management techniques, concerns over the possibility of negative consequences to animals are expressed most frequently for social housing and destructible enrichment, while skepticism regarding efficacy is limited almost exclusively to sensory enrichment. Behavioral management program staffing has expanded over time in the facilities surveyed, due not only to increased numbers of dedicated behavioral management technicians but also to greater involvement of animal care technicians, suggesting an increase in the integration of behavioral care into animal husbandry. Broad awareness of common practice may assist facilities with program evaluation and assessment of progress in the field can generate recommendations for continuing the advancement of primate behavioral management programs. PMID:26971575

A far-infrared spatial/spectral Fourier interferometry laboratory-based testbed instrument

NASA Astrophysics Data System (ADS)

Spencer, Locke D.; Naylor, David A.; Scott, Jeremy P.; Weiler, Vince F.; MacCrimmon, Roderick K.; Sitwell, Geoffrey R. H.; Ade, Peter A. R.

2016-07-01

We describe the current status, including preliminary design, characterization efforts, and recent progress, in the development of a spatial/spectral double Fourier laboratory-based interferometer testbed instrument within the Astronomical Instrumentation Group (AIG) laboratories at the University of Lethbridge, Canada (UL). Supported by CRC, CFI, and NSERC grants, this instrument development will provide laboratory demonstration of spatial-spectral interferometry with a concentration of furthering progress in areas including the development of spatial/spectral interferometry observation, data processing, characterization, and analysis techniques in the Far-Infrared (FIR) region of the electromagnetic spectrum.

Mitigating preventable chronic disease: Progress report of the Cleveland Clinic's Lifestyle 180 program

PubMed Central

2011-01-01

Background Poor lifestyle choices are key in development and progression of preventable chronic diseases. The purpose of the study was to design and test a program to mitigate the physical and fiscal consequences of chronic diseases. Methods Here we report the outcomes for 429 participants with one or more chronic conditions, including obesity, hypertension, hyperlipidemia and diabetes mellitus, many of whom had failed traditional disease management programs, who enrolled into a comprehensive lifestyle intervention. The Lifestyle 180 program integrates nutrition, physical activity and stress management interventions and was conducted at the Wellness Institute of the Cleveland Clinic, United States. An intensive 6 week immersion course, with 8 hours of group instruction per week, was followed by 3 follow-up, 4 hour-long sessions over the course of 6 months. Results Changes in biometric (weight, height, waist circumference, resting heart rate and blood pressure) and laboratory variables (fasting lipid panel, blood glucose, insulin, hemoglobin A1c, ultra sensitive C-reactive protein) at 6 months were compared with baseline (pre-post analysis). At week 30, biometric and laboratory data were available for 244 (57%) and 299 (70%) participants, respectively. These had a mean ± SD reduction in weight (6.8 ± 6.9 kg, P < 0.001), waist circumference (6.1 ± 7.3 cm, P < 0.001), glucose (4.5 ± 29.6 mg/dL or 0.25 ± 1.64 mmol/L, P = 0.009), triglycerides (26.4 ± 58.5 mg/dL or 0.30 ± 0.66 mmol/L, P < 0.001), low-density lipoprotein cholesterol (LDL) (7.9 ± 25.1 mg/dL or 0.2 ± 0.65 mmol/L, P < 0.001), hemoglobin A1c (HgbA1c) (0.20 ± 0.64%, P = 0.001), insulin (3.8 ± 11 microU/ml or 26.6 ± 76.4 ρmol, P < 0.001) and ultra sensitive C-reactive protein (US - CRP) (0.9 ± 4.8 mg/dL or 7.3 ± 40.2 nmol/L, P = 0.012), an increase in mean high-density lipoprotein cholesterol (HDL) (3.7 ± 8.4 mg/dL or 0.1 ± 0.22, P < 0.001), and decreased use of medications. Conclusion Implementation of a comprehensive lifestyle modification program among adults with common chronic conditions results in significant and clinically meaningful improvements in biometric and laboratory outcomes after 6 months. PMID:22112436

Project 8, Phase III Design: Placing an eV-Scale Limit on the Neutrino Mass using Cyclotron Radiation Emission Spectroscopy

NASA Astrophysics Data System (ADS)

Oblath, Noah; Project 8 Collaboration

2016-09-01

We report on the design concept for Phase III of the Project 8 experiment. In the third phase of Project 8 we aim to place a limit on the neutrino mass that is similar to the current limits set by tritium beta-decay experiments, mν < 2eV . From the first two phases of Project 8 we move to a novel design consisting of a 100cm3 cylindrical volume of tritium gas instrumented with two 30-element rings of inward-facing antennas. Beam-forming techniques similar to those used in radioastronomy will be employed to search for and track electron signals in the fiducial volume. This talk will present the quantitative design concept for the phased-array receiver, and illustrate how we are progressing towards the Phase IV experiment, which will have sensitivity to the neutrino mass scale allowed by the inverted mass hierarchy. This work is supported by the DOE Office of Science Early Career Research Program, and the Laboratory Directed Research and Development Program at Pacific Northwest National Laboratory.

Experimental Estimation Of Energy Damping During Free Rocking Of Unreinforced Masonry Walls. First Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sorrentino, Luigi; Masiani, Renato; Benedetti, Stefano

2008-07-08

This paper presents an ongoing experimental program on unreinforced masonry walls undergoing free rocking. Aim of the laboratory campaign is the estimation of kinetic energy damping exhibited by walls released with non-zero initial conditions of motion. Such energy damping is necessary for dynamic modelling of unreinforced masonry local mechanisms. After a brief review of the literature on this topic, the main features of the laboratory tests are presented. The program involves the experimental investigation of several parameters: 1) unit material (brick or tuff), 2) wall aspect ratio (ranging between 14.5 and 7.1), 3) restraint condition (two-sided or one-sided rocking), andmore » 4) depth of the contact surface between facade and transverse walls (one-sided rocking only). All walls are single wythe and the mortar is pozzuolanic. The campaign is still in progress. However, it is possible to present the results on most of the mechanical properties of mortar and bricks. Moreover, a few time histories are reported, already indicating the need to correct some of the assumptions frequent in the literature.« less

Pacific Northwest Laboratory annual report for 1989 to the DOE Office of Energy Research - Part 1: Biomedical Sciences

DOE Office of Scientific and Technical Information (OSTI.GOV)

Park, J.F.

This report summarizes progress on OHER human health, biological, general life sciences, and medical applications research programs conducted at PNL in FY 1989. The research develops the knowledge and scientific principles necessary to identify, understand, and anticipate the long-term health consequences of energy-related radiation and chemicals. Our continuing emphasis is to decrease the uncertainty of health risk estimates from existing and developing energy-related technologies through an increased understanding of how radiation and chemicals cause biological damage. The sequence of this report of PNL research reflects the OHER programmatic structure. The first section, on human health research, concerns statistical and epidemiologicalmore » studies for assessing health risks. The next section contains reports of biological research in laboratory animals and in vitro cell systems, including research with radionuclides and chemicals. The general life sciences research section reports research conducted for the OHER human genome research program, and the medical applications section summarizes commercial radioisotope production and distribution activities at DOE facilities. 6 refs., 50 figs., 35 tabs.« less

Single Axis Flywheel IPACS @1300W, 0.8 N-m

NASA Technical Reports Server (NTRS)

Jansen, Ralph; Kenny, Barbara; Kascak, Peter; Dever, Tim; Santiago, Walter

2005-01-01

NASA Glenn Research Center is developing flywheels for space systems. A single axis laboratory version of an integrated power and attitude control (IPACs) system has been experimentally demonstrated. This is a significant step on the road to a flight qualified three axes IPACS system. The presentation outlines the flywheel development process at NASA GRC, the experimental hardware and approach, the IPACS control algorithm that was formulated and the results of the test program and then proposes a direction for future work. GRC has made progress on flywheel module design in terms of specific energy density and capability through a design and test program resulting in three flywheel module designs. Two of the flywheels are used in the 1D-IPACS experiment with loads and power sources to simulate a satellite power system. The system response is measured in three power modes: charge, discharge, and charge reduction while simultaneously producing a net output torque which could be used for attitude control. Finally, recommendations are made for steps that should be taken to evolve from this laboratory demonstration to a flight like system.

Analytical Chemistry Division annual progress report for period ending December 31, 1988

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The Analytical Chemistry Division of Oak Ridge National Laboratory (ORNL) is a large and diversified organization. As such, it serves a multitude of functions for a clientele that exists both in and outside of ORNL. These functions fall into the following general categories: (1) Analytical Research, Development, and Implementation. The division maintains a program to conceptualize, investigate, develop, assess, improve, and implement advanced technology for chemical and physicochemical measurements. Emphasis is on problems and needs identified with ORNL and Department of Energy (DOE) programs; however, attention is also given to advancing the analytical sciences themselves. (2) Programmatic Research, Development, andmore » Utilization. The division carries out a wide variety of chemical work that typically involves analytical research and/or development plus the utilization of analytical capabilities to expedite programmatic interests. (3) Technical Support. The division performs chemical and physicochemical analyses of virtually all types. The Analytical Chemistry Division is organized into four major sections, each of which may carry out any of the three types of work mentioned above. Chapters 1 through 4 of this report highlight progress within the four sections during the period January 1 to December 31, 1988. A brief discussion of the division's role in an especially important environmental program is given in Chapter 5. Information about quality assurance, safety, and training programs is presented in Chapter 6, along with a tabulation of analyses rendered. Publications, oral presentations, professional activities, educational programs, and seminars are cited in Chapters 7 and 8.« less

Hydrologic Resources Management Program and Underground Tests Area Project FY 2003 Progress Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

J., B C; F., E G; K., E B

This report describes FY 2003 technical studies conducted by the Chemical Biology and Nuclear Science Division (CBND) at Lawrence Livermore National Laboratory (LLNL) in support of the Hydrologic Resources Management Program (HRMP) and the Underground Test Area (UGTA) Project. These programs are administered by the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office (NNSA/NSO) through the Defense Programs and Environmental Restoration Divisions, respectively. HRMP-sponsored work is directed toward the responsible management of the natural resources at the Nevada Test Site (NTS), enabling its continued use as a staging area for strategic operations in support of national security.more » UGTA-funded work emphasizes the development of an integrated set of groundwater flow and contaminant transport models to predict the extent of radionuclide migration from underground nuclear testing areas at the NTS. The present report is organized on a topical basis and contains five chapters that reflect the range of technical work performed by LLNL-CBND during FY 2003. Although we have emphasized investigations that were led by CBND, we also participated in a variety of collaborative studies with other UGTA and HRMP contract organizations including the Energy and Environment Directorate at LLNL (LLNL-E&E), Los Alamos National Laboratory (LANL), the Desert Research Institute (DRI), the U.S. Geological Survey (USGS), Stoller-Navarro Joint Venture (SNJV), and Bechtel Nevada (BN).« less

Summer Research Program (1992). Summer Faculty Research Program (SFRP) Reports. Volume 5A. Wright Laboratory

DTIC Science & Technology

1992-12-01

1992 6-~1 SOME RESULTS IN MACIIINE- LEARNING Mike Breen Assistant Professor Department of Mathematics Tennessee Technological Universitv Abstract The...Research Laboratory; Wilford Hall Medical Center 12 High School Apprenticeship Program Reports: Armstrong Laboratory 13 High School Apprenticeship ...Program Reports: Phillips Laboratory 14 High School Apprenticeship Program Reports: Rome Laboratory 15 High School Apprenticeship Program Reports

Laboratory Directed Research and Development Program FY2016 Annual Summary of Completed Projects

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

ORNL FY 2016 Annual Summary of Laboratory Directed Research and Development Program (LDRD) Completed Projects. The Laboratory Directed Research and Development (LDRD) program at ORNL operates under the authority of DOE Order 413.2C, “Laboratory Directed Research and Development” (October 22, 2015), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. The LDRD program funds are obtained through a charge to all Laboratory programs. ORNL reports its status to DOE in March of each year.

High Temperature Steam Electrolysis: Demonstration of Improved Long-Term Performance

DOE Office of Scientific and Technical Information (OSTI.GOV)

J. E. O'Brien; X. Zhang; R. C. O'Brien

2011-11-01

Long-term performance is an ongoing issue for hydrogen production based on high-temperature steam electrolysis (HTSE). For commercial deployment, solid-oxide electrolysis stacks must achieve high performance with long-term degradation rates of {approx}0.5%/1000 hours or lower. Significant progress has been achieved toward this goal over the past few years. This paper will provide details of progress achieved under the Idaho National Laboratory high temperature electrolysis research program. Recent long-term stack tests have achieved high initial performance with degradation rates less than 5%/khr. These tests utilize internally manifolded stacks with electrode-supported cells. The cell material sets are optimized for the electrolysis mode ofmore » operation. Details of the cells and stacks will be provided along with details of the test apparatus, procedures, and results.« less

Laboratory Directed Research and Development FY2011 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Craig, W; Sketchley, J; Kotta, P

2012-03-22

A premier applied-science laboratory, Lawrence Livermore National Laboratory (LLNL) has earned the reputation as a leader in providing science and technology solutions to the most pressing national and global security problems. The LDRD Program, established by Congress at all DOE national laboratories in 1991, is LLNL's most important single resource for fostering excellent science and technology for today's needs and tomorrow's challenges. The LDRD internally directed research and development funding at LLNL enables high-risk, potentially high-payoff projects at the forefront of science and technology. The LDRD Program at Livermore serves to: (1) Support the Laboratory's missions, strategic plan, and foundationalmore » science; (2) Maintain the Laboratory's science and technology vitality; (3) Promote recruiting and retention; (4) Pursue collaborations; (5) Generate intellectual property; and (6) Strengthen the U.S. economy. Myriad LDRD projects over the years have made important contributions to every facet of the Laboratory's mission and strategic plan, including its commitment to nuclear, global, and energy and environmental security, as well as cutting-edge science and technology and engineering in high-energy-density matter, high-performance computing and simulation, materials and chemistry at the extremes, information systems, measurements and experimental science, and energy manipulation. A summary of each project was submitted by the principal investigator. Project summaries include the scope, motivation, goals, relevance to DOE/NNSA and LLNL mission areas, the technical progress achieved in FY11, and a list of publications that resulted from the research. The projects are: (1) Nuclear Threat Reduction; (2) Biosecurity; (3) High-Performance Computing and Simulation; (4) Intelligence; (5) Cybersecurity; (6) Energy Security; (7) Carbon Capture; (8) Material Properties, Theory, and Design; (9) Radiochemistry; (10) High-Energy-Density Science; (11) Laser Inertial-Fusion Energy; (12) Advanced Laser Optical Systems and Applications; (12) Space Security; (13) Stockpile Stewardship Science; (14) National Security; (15) Alternative Energy; and (16) Climatic Change.« less

Department of Defense Tri-Service Precision Machine-Tool Program. Quarterly report, February--April 1978

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1978-06-01

Following a planning period during which the Lawrence Livermore Laboratory and the Department of Defense managing sponsor, the USAF Materials Laboratory, agreed on work statements, the Department of Defense Tri-Service Precision Machine-Tool Program began in February 1978. Milestones scheduled for the first quarter have been met. Tasks and manpower requirements for two basic projects, precision-machining commercialization (PMC) and a machine-tool task force (MTTF), were defined. Progress by PMC includes: (1) documentation of existing precision machine-tool technology by initiation and compilation of a bibliography containing several hundred entries: (2) identification of the problems and needs of precision turning-machine builders and ofmore » precision turning-machine users interested in developing high-precision machining capability; and (3) organization of the schedule and content of the first seminar, to be held in October 1978, which will bring together representatives from the machine-tool and optics communities to address the problems and begin the process of high-precision machining commercialization. Progress by MTTF includes: (1) planning for the organization of a team effort of approximately 60 to 80 international experts to contribute in various ways to project objectives, namely, to summarize state-of-the-art cutting-machine-tool technology and to identify areas where future R and D should prove technically and economically profitable; (2) preparation of a comprehensive plan to achieve those objectives; and (3) preliminary arrangements for a plenary session, also in October, when the task force will meet to formalize the details for implementing the plan.« less

Stabilized Liner Compressor: The Return of Linus

NASA Astrophysics Data System (ADS)

Turchi, Peter; Frese, Sherry; Frese, Michael; Mielke, Charles; Hinrichs, Mark; Nguyen, Doan

2015-11-01

To access the lower cost regime of magneto-inertial fusion at megagauss magnetic field-levels requires the use of dynamic conductors in the form of imploding cylindrical shells, aka, liners. Such liner implosions can compress magnetic flux and plasma to attain fusion conditions, but are subject to Rayleigh-Taylor instabilities, both in the launch and recovery of the liner material and in the final few diameters of implosion. These instabilities were overcome in the Linus program at the Naval Research Laboratory, c. 1979, providing the experimentally-demonstrated basis for repetitive operation and leading to an economical reactor concept at low fusion gain. The recent ARPA-E program for low-cost fusion technology has revived interest in this approach. We shall discuss progress in modeling and design of a Stabilized Liner Compressor (SLC) that extends the earlier work to higher pressures and liner speeds appropriate to potential plasma targets. Sponsored by ARPA-E ALPHA Program.

Wisconsin Twin Research: early development, childhood psychopathology, autism, and sensory over-responsivity.

PubMed

Schmidt, Nicole L; Van Hulle, Carol A; Brooker, Rebecca J; Meyer, Lauren R; Lemery-Chalfant, Kathryn; Goldsmith, H Hill

2013-02-01

The Wisconsin Twin Research Program comprises multiple longitudinal studies that utilize a panel recruited from statewide birth records for the years 1989 through 2004. Our research foci are the etiology and developmental course of early emotions, temperament, childhood anxiety and impulsivity, autism, sensory over-responsivity, and related topics. A signature feature of this research program is the breadth and depth of assessment during key periods of development. The assessments include extensive home- and laboratory-based behavioral batteries, recorded sibling and caregiver interactions, structured psychiatric interviews with caregivers and adolescents, observer ratings of child behavior, child self-report, cognitive testing, neuroendocrine measures, medical records, dermatoglyphics, genotyping, and neuroimaging. Across the various studies, testing occasions occurred between 3 months and 18 years of age. Data collection for some aspects of the research program has concluded and, for other aspects, longitudinal follow-ups are in progress.

Wisconsin Twin Research: Early Development, Childhood Psychopathology, Autism, and Sensory Over-responsivity

PubMed Central

Schmidt, Nicole L.; Van Hulle, Carol; Brooker, Rebecca J.; Meyer, Lauren R.; Lemery-Chalfant, Kathryn; Goldsmith, H. H.

2012-01-01

The Wisconsin Twin Research Program comprises multiple longitudinal studies that utilize a panel recruited from statewide birth records for the years 1989 through 2004. Our research foci are the etiology and developmental course of early emotions, temperament, childhood anxiety and impulsivity, autism, sensory over-responsivity, and related topics. A signature feature of this research program is the breadth and depth of assessment during key periods of development. The assessments include extensive home and laboratory-based behavioral batteries, recorded sibling and caregiver interactions, structured psychiatric interviews with caregivers and adolescents, observer ratings of child behavior, child self-report, cognitive testing, neuroendocrine measures, medical records, dermatoglyphics, genotyping, and neuroimaging. Across the various studies, testing occasions occurred between 3 months and 18 years of age. Data collection for some aspects of the research program has concluded and, for other aspects, longitudinal follow-ups are in progress. PMID:23200241

Multi-Disciplinary Type Creativity Education for Students from 15 years old to Bachelor Level in College of Technology

NASA Astrophysics Data System (ADS)

Yotsuyanagi, Takao; Ikeda, Senri; Suzuki, Katsuhiko; Kobayashi, Hiroshi; Sakuraba, Hiroshi; Shoji, Akira; Itoh, Masahiko

Creativity is the most fundamental keyword for engineers to solve the various problems in manufacturing products. This engineering “learning” cannot be achieved without the real experiences, especially by the teens who have the curiosity to know everything. New educational program has been innovated in Miyagi National College of Technology. This new curriculum started as “03C” in 2003. It involves two laboratories for mixed-departments type grouping, which intend to cultivate the creative ability for the 2nd year students in College Course and the 1st year students in Advanced Course as Engineering Design. This paper presents the trial of the new educational program on the cultivating creative ability designed for teen-agers, and discusses the processes in detail, results and further problems. This program will progress still more with continuous improvement of manufacturing subjects in cooperative with educational-industrial complex.

Trends in Testing for Mycobacterium tuberculosis Complex From US Public Health Laboratories, 2009-2013.

PubMed

Tyrrell, Frances; Stafford, Cortney; Yakrus, Mitchell; Youngblood, Monica; Hill, Andrew; Johnston, Stephanie

We investigated data from US public health laboratories funded through the Centers for Disease Control and Prevention's Tuberculosis Elimination and Laboratory Cooperative Agreement to document trends and challenges in meeting national objectives in tuberculosis (TB) laboratory diagnoses. We examined data on workload and turnaround time from public health laboratories' progress reports during 2009-2013. We reviewed methodologies, laboratory roles, and progress toward rapid detection of Mycobacterium tuberculosis complex through nucleic acid amplification (NAA) testing. We compared selected data with TB surveillance reports to estimate public health laboratories' contribution to national diagnostic services. During the study period, culture and drug susceptibility tests decreased, but NAA testing increased. Public health laboratories achieved turnaround time benchmarks for drug susceptibility tests at lower levels than for acid-fast bacilli smear and identification from culture. NAA positivity in laboratories among surveillance-reported culture-positive TB cases increased from 26.6% (2355 of 8876) in 2009 to 40.0% (2948 of 7358) in 2013. Public health laboratories provided an estimated 50.9% (4285 of 8413 in 2010) to 57.2% (4210 of 7358 in 2013) of culture testing and 88.3% (6822 of 7727 in 2011) to 94.4% (6845 of 7250 in 2012) of drug susceptibility tests for all US TB cases. Public health laboratories contribute substantially to TB diagnoses in the United States. Although testing volumes mostly decreased, the increase in NAA testing indicates continued progress in rapid M tuberculosis complex detection.

(Photosynthesis in intact plants)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

Progress in the two years since the last renewal application has been excellent. We have made substantial contributions on both main fronts of the projects, and are particularly happy with the progress of our research on intact plants. The approach of basing our field work on a sound foundation of laboratory studies has enabled is to use methods which provide unambiguous assays of well characterized reactions. We have also made excellent progress in several laboratory studies which will have direct applications in future field work, and have introduced to the laboratory a range of molecular genetics techniques which will allowmore » us to explore new options in the attempt to understand function at the level of molecular structure.« less

Laboratory Automation and Middleware.

PubMed

Riben, Michael

2015-06-01

The practice of surgical pathology is under constant pressure to deliver the highest quality of service, reduce errors, increase throughput, and decrease turnaround time while at the same time dealing with an aging workforce, increasing financial constraints, and economic uncertainty. Although not able to implement total laboratory automation, great progress continues to be made in workstation automation in all areas of the pathology laboratory. This report highlights the benefits and challenges of pathology automation, reviews middleware and its use to facilitate automation, and reviews the progress so far in the anatomic pathology laboratory. Copyright © 2015 Elsevier Inc. All rights reserved.

Publications of the Jet Propulsion Laboratory, 1981

NASA Technical Reports Server (NTRS)

1982-01-01

Over 500 externally distributed technical reports released during 1981 that resulted from scientific and engineering work performed, or managed by Jet Propulsion Laboratory are listed by primary author. Of the total number of entries, 311 are from the bimonthly Deep Space Network Progress Report, and its successor, the Telecommunications and Data Acquisition Progress Report.

Progress in increasing electronic reporting of laboratory results to public health agencies--United States, 2013.

PubMed

2013-09-27

Electronic reporting of laboratory results to public health agencies can improve public health surveillance for reportable diseases and conditions by making reporting more timely and complete. Since 2010, CDC has provided funding to 57 state, local, and territorial health departments through the Epidemiology and Laboratory Capacity for Infectious Diseases cooperative agreement to assist with improving electronic laboratory reporting (ELR) from clinical and public health laboratories to public health agencies. As part of this agreement, CDC and state and large local health departments are collaborating to monitor ELR implementation in the United States by developing data from each jurisdiction regarding total reporting laboratories, laboratories sending ELR by disease category and message format, and the number of ELR laboratory reports compared with the total number of laboratory reports. At the end of July 2013, 54 of the 57 jurisdictions were receiving at least some laboratory reports through ELR, and approximately 62% of 20 million laboratory reports were being received electronically, compared with 54% in 2012. Continued progress will require collaboration between clinical laboratories, laboratory information management system (LIMS) vendors, and public health agencies.

Extra-analytical quality indicators and laboratory performances.

PubMed

Sciacovelli, Laura; Aita, Ada; Plebani, Mario

2017-07-01

In the last few years much progress has been made in raising the awareness of laboratory medicine professionals about the effectiveness of quality indicators (QIs) in monitoring, and improving upon, performances in the extra-analytical phases of the Total Testing Process (TTP). An effective system for management of QIs includes the implementation of an internal assessment system and participation in inter-laboratory comparison. A well-designed internal assessment system allows the identification of critical activities and their systematic monitoring. Active participation in inter-laboratory comparison provides information on the performance level of one laboratory with respect to that of other participating laboratories. In order to guarantee the use of appropriate QIs and facilitate their implementation, many laboratories have adopted the Model of Quality Indicators (MQI) proposed by Working Group "Laboratory Errors and Patient Safety" (WG-LEPS) of IFCC, since 2008, which is the result of international consensus and continuous experimentation, and updating to meet new, constantly emerging needs. Data from participating laboratories are collected monthly and reports describing the statistical results and evaluating laboratory data, utilizing the Six Sigma metric, issued regularly. Although the results demonstrate that the processes need to be improved upon, overall the comparison with data collected in 2014 shows a general stability of quality levels and that an improvement has been achieved over time for some activities. The continuous monitoring of QI data allows identification all possible improvements, thus highlighting the value of participation in the inter-laboratory program proposed by WG-LEPS. The active participation of numerous laboratories will guarantee an ever more significant State-of-the-Art, promote the reduction of errors and improve quality of the TTP, thus guaranteeing patient safety. Copyright © 2017. Published by Elsevier Inc.

The RERTR Program status and progress

DOE Office of Scientific and Technical Information (OSTI.GOV)

Travelli, A.

1995-12-01

The progress of the Reduced Enrichment Research and Test Reactor (RERTR) Program is described. The major events, findings, and activities of 1995 are reviewed after a brief summary of the results which the RERTR Program had achieved by the end of 1994. The revelation that Iraq was on the verge of developing a nuclear weapon at the time of the Gulf War, and that it was planning to do so by extracting HEU from the fuel of its research reactors, has given new impetus and urgency to the RERTR commitment of eliminating HEU use in research and test reactors worldwide.more » Development of advanced LEU research reactor fuels is scheduled to begin in October 1995. The Russian RERTR program, which aims to develop and demonstrate within the next five years the technical means needed to convert Russian-supplied research reactors to LEU fuels, is now in operation. A Statement of Intent was signed by high US and Chinese officials, endorsing cooperative activities between the RERTR program and Chinese laboratories involved in similar activities. Joint studies of LEU technical feasibility were completed for the SAFARI-I reactor in South Africa and for the ANS reactor in the US. A new study has been initiated for the FRM-II reactor in Germany. Significant progress was made on several aspects of producing {sup 99}Mo from fission targets utilizing LEU instead of HEU. A cooperation agreements is in place with the Indonesian BATAN. The first prototypical irradiation of an LEU metal-foil target for {sup 99}Mo production was accomplished in Indonesia. The TR-2 reactor, in Turkey, began conversion. SAPHIR, in Switzerland, was shut down. LEU fuel fabrication has begun for the conversion of two more US reactors. Twelve foreign reactors and nine domestic reactors have been fully converted. Approximately 60 % of the work required to eliminate the use of HEU in US-supplied research reactors has been accomplished.« less

Effects of unique biomedical education programs for engineers: REDEEM and ESTEEM projects.

PubMed

Matsuki, Noriaki; Takeda, Motohiro; Yamano, Masahiro; Imai, Yohsuke; Ishikawa, Takuji; Yamaguchi, Takami

2009-06-01

Current engineering applications in the medical arena are extremely progressive. However, it is rather difficult for medical doctors and engineers to discuss issues because they do not always understand one another's jargon or ways of thinking. Ideally, medical engineers should become acquainted with medicine, and engineers should be able to understand how medical doctors think. Tohoku University in Japan has managed a number of unique reeducation programs for working engineers. Recurrent Education for the Development of Engineering Enhanced Medicine has been offered as a basic learning course since 2004, and Education through Synergetic Training for Engineering Enhanced Medicine has been offered as an advanced learning course since 2006. These programs, which were developed especially for engineers, consist of interactive, modular, and disease-based lectures (case studies) and substantial laboratory work. As a result of taking these courses, all students obtained better objective outcomes, on tests, and subjective outcomes, through student satisfaction. In this article, we report on our unique biomedical education programs for engineers and their effects on working engineers.

DOE Solar Energy Technologies Program FY 2005 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The DOE Solar Energy Technologies Program FY 2005 Annual Report chronicles the R&D results of the U.S. Department of Energy Solar Energy Technologies Program for Fiscal Year 2005. In particular, the report describes R&D performed by the Program?s national laboratories (National Renewable Energy Laboratory, Sandia National Laboratories, Oak Ridge National Laboratory, and Brookhaven National Laboratory) and university and industry partners.

ISO Guest Observer Data Analysis and LWS Instrument Team Activities

NASA Technical Reports Server (NTRS)

Smith, Howard

2001-01-01

The following is an interim annual report. Dr. Smith is currently on an extended TDY to the Istituto di Fisica dello Spazio Interplanetario (IFSI) at the Consilio Nazionale delle Richerche (CNR) in Rome, Italy, where he has been working on a related NASA grant in support of analysis of Infrared Space Observatory (ISO) data on star formation in Ultra Luminous Infrared Galaxies and our galaxy. Work emphasizes development of metal mesh grids for use in spacecraft, and the design and fabrication of test elements by the Naval Research Laboratory, Washington D.C. Work has progressed well, but slowly, on that program due to the departure of a key engineer. NASA has been advised of the delay, and granted a no-cost extension, whereby SAO has authorized a delay in the final report from NRL. Nevertheless NRL has continued to make progress. Two papers have been submitted to refereed journals related to this program, and a new design for mesh operating in the 20-40 micron region has been developed. Meetings continue through the summer on these items. A new technical scientist has been made a job offer and hopefully will be on board NRL shortly, although most of the present grant work is already completed. A more complete report, with copies of the submitted papers, designs, and other measures of progress, will be submitted to NASA in September when Dr. Smith returns from his current TDY.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Green, D.W.; Boparai, A.S.; Bowers, D.L.

This report summarizes the activities of the Analytical Chemistry Laboratory (ACL) at Argonne National Laboratory (ANL) for Fiscal Year (FY) 2000 (October 1999 through September 2000). This annual progress report, which is the seventeenth in this series for the ACL, describes effort on continuing projects, work on new projects, and contributions of the ACL staff to various programs at ANL. The ACL operates within the ANL system as a full-cost-recovery service center, but it has a mission that includes a complementary research and development component: The Analytical Chemistry Laboratory will provide high-quality, cost-effective chemical analysis and related technical support tomore » solve research problems of our clients--Argonne National Laboratory, the Department of Energy, and others--and will conduct world-class research and development in analytical chemistry and its applications. The ACL handles a wide range of analytical problems that reflects the diversity of research and development (R&D) work at ANL. Some routine or standard analyses are done, but the ACL operates more typically in a problem-solving mode in which development of methods is required or adaptation of techniques is needed to obtain useful analytical data. The ACL works with clients and commercial laboratories if a large number of routine analyses are required. Much of the support work done by the ACL is very similar to applied analytical chemistry research work.« less

Consolidated fuel reprocessing program

NASA Astrophysics Data System (ADS)

1985-02-01

Improved processes and components for the Breeder Reprocessing Engineering Test (BRET) were identified and developed as well as the design, procurement and development of prototypic equipment. The integrated testing of process equipment and flowsheets prototypical of a pilot scale full reprocessing plant, and also for testing prototypical remote features of specific complex components in the system are provided. Information to guide the long range activities of the Consolidated Fuel Reprocessing Program (CERP), a focal point for foreign exchange activities, and support in specialized technical areas are described. Research and development activities in HTGR fuel treatment technology are being conducted. Head-end process and laboratory scale development efforts, as well as studies specific to HTGR fuel, are reported. The development of off-gas treatment processes has generic application to fuel reprocessing, progress in this work is also reported.

Laser-based firing systems for prompt initiation of secondary explosives

NASA Technical Reports Server (NTRS)

Meeks, Kent D.; Setchell, Robert E.

1993-01-01

Motivated by issues of weapon safety and security, laser based firing systems for promptly initiating secondary explosives have been under active development at Sandia National Laboratories for more than four years. Such a firing system consists of miniaturized, Q-switched, solid-state laser, optical detonators, optical safety switches, and elements for splitting, coupling, and transmitting the laser output. Potential system applications pose significant challenges in terms of server mechanical and thermal environments and packaging constraints, while requiring clear demonstration of safety enhancements. The Direct Optical Initiation (DOI) Program at Sandia is addressing these challenges through progress development phases during which the design, fabrication, and testing of prototype hardware is aimed at more difficult application requirements. A brief history of the development program, and a summary of current and planned activities, will be presented.

Psychological Usability of Layered Application Software Platforms

NASA Technical Reports Server (NTRS)

Uhiarik, John

1999-01-01

This grant provided Graduate Research Fellowship Program support to James Michael Herold to obtain a graduate degree from the Department of Psychology at Kansas State University and conduct usability testing of graphical user interfaces the Kennedy Space Center. The student independently took an additional internship at Boll Laboratories without informing his graduate advisor or the Department of Psychology. Because he was NOT making progress toward his degree, he elected not to pursue his graduate studies at Kansas State University and self-terminated from the program (spin without informing his advisor or the Department of Psychology]. What he accomplished for NASA in terms of usability testing at the Kennedy Space Center is unclear. NASA terminated support for the project: 07/30/99, including a $4,000 commitment to provide infrastructure support to the Department of Psychology.

Technology readiness levels for the new millennium program

NASA Technical Reports Server (NTRS)

Moynihan, P. I.; Minning, C. P.; Stocky, J. F.

2003-01-01

NASA's New Millennium Program (NMP) seeks to advance space exploration by providing an in-space validating mechanism to verify the maturity of promising advanced technologies that cannot be adequately validated with Earth-based testing alone. In meeting this objective, NMP uses NASA Technology Readiness Levels (TRL) as key indicators of technology advancement and assesses development progress against this generalized metric. By providing an opportunity for in-space validation, NMP can mature a suitable advanced technology from TRL 4 (component and/or breadboard validation in laboratory environment) to a TRL 7 (system prototype demonstrated in an Earth-based space environment). Spaceflight technology comprises a myriad of categories, types, and functions, and as each individual technology emerges, a consistent interpretation of its specific state of technological advancement relative to other technologies is problematic.

Perceptions and attitudes toward SLMTA amongst laboratory and hospital professionals in Ethiopia.

PubMed

Lulie, Adino D; Hiwotu, Tilahun M; Mulugeta, Achamyeleh; Kebede, Adisu; Asrat, Habtamu; Abebe, Abnet; Yenealem, Dereje; Abose, Ebise; Kassa, Wondwossen; Kebede, Amha; Linde, Mary K; Ayana, Gonfa

2014-01-01

Strengthening Laboratory Management Toward Accreditation (SLMTA) is a competency-based management training programme. Assessing health professionals' views of SLMTA provides feedback to inform program planning, implementation and evaluation of SLMTA's training, communication and mentorship components. To assess laboratory professionals' and hospital chief executive officers' (CEOs) perceptions and attitudes toward the SLMTA programme in Ethiopia. A cross-sectional descriptive survey was conducted in March 2013 using a structured questionnaire to collect qualitative data from 72 laboratory professionals and hospital CEOs from 17 health facilities, representing all regions and two city administrations in Ethiopia. Focus groups were conducted with laboratory professionals and hospital administration to gain insight into the strengths and challenges of the SLMTA programme so as to guide future planning and implementation. Ethiopian laboratory professionals at all levels had a supportive attitude toward the SLMTA programme. They believed that SLMTA substantially improved laboratory services and acted as a catalyst for total healthcare reform and improvement. They also noted that the SLMTA programme achieved marked progress in laboratory supply chain, sample referral, instrument maintenance and data management systems. In contrast, nearly half of the participating hospital CEOs, especially those associated with low-scoring laboratories, were sceptical about the SLMTA programme, believing that the benefits of SLMTA were outweighed by the level of human resources and time commitment required. They also voiced concerns about the cost and sustainability of SLMTA. This study highlights the need for stronger engagement and advocacy with hospital administration and the importance of addressing concerns about the cost and sustainability of the SLMTA programme.

42 CFR 493.645 - Additional fee(s) applicable to approved State laboratory programs and laboratories issued a...

Code of Federal Regulations, 2011 CFR

2011-10-01

..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS General Administration § 493.645 Additional fee(s) applicable to approved State laboratory programs and... laboratory programs and laboratories issued a certificate of accreditation, certificate of waiver, or...

Pacific Northwest Laboratory Annual Report for 1992 to the DOE Office of Energy Research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kreml, S.A.; Park, J.F.

1993-06-01

This report summarizes progress in OHER biological research and general life sciences research programs conducted at PNL in FY 1992. The research develops the knowledge and fundamental principles necessary to identify, understand, and anticipate the long-term health consequences of energy-related radiation and chemicals. Our continuing emphasis is to decrease the uncertainty of health risk estimates from energy-related technologies through an increase understanding of the ways in which radiation and chemicals cause biological damage. Descriptors of individual research projects as detailed in this report one separately abstracted and indexed for the database.

Electric and magnetic fields. Hearing before the Subcommittee on Energy and Power of the Committee on Energy and Commerce, House of Representatives, One Hundred Third Congress, First Session, April 1, 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-01-01

This hearing focuses on progress on implementing federal legislation establishing a coordinated Federal research and public information program in Electromagnetic fields. Testimony is given by F.Keith, Center for Risk Management, Resources for the Future; R. Neutra, Environmental Health Investigations, California Department of Health Services; K.Olden, National Institute of Environmental Health Sciences; R. San Martin, Acting Ass Sec, Conservation and Renewable Energy, DOE; T. Tenforde, Life Sciences Center, Battelle Pacific Northwest Laboratories.

Year One Summary of X-energy Pebble Fuel Development at ORNL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Helmreich, Grant W.; Hunn, John D.; McMurray, Jake W.

2017-06-01

The Advanced Reactor Concepts X-energy (ARC-Xe) Pebble Fuel Development project at Oak Ridge National Laboratory (ORNL) has successfully completed its first year, having made excellent progress in accomplishing programmatic objectives. The primary focus of research at ORNL in support of X-energy has been the training of X-energy fuel fabrication engineers and the establishment of US pebble fuel production capabilities able to supply the Xe-100 pebble-bed reactor. These efforts have been strongly supported by particle fuel fabrication and characterization expertise present at ORNL from the Advanced Gas Reactor (AGR) Fuel Development and Qualification Program.

Technology developments toward 30-year-life of photovoltaic modules

NASA Technical Reports Server (NTRS)

Ross, R. G., Jr.

1984-01-01

As part of the United States National Photovoltaics Program, the Jet Propulsion Laboratory's Flat-Plate Solar Array Project (FSA) has maintained a comprehensive reliability and engineering sciences activity addressed toward understanding the reliability attributes of terrestrial flat-plate photovoltaic arrays and to deriving analysis and design tools necessary to achieve module designs with a 30-year useful life. The considerable progress to date stemming from the ongoing reliability research is discussed, and the major areas requiring continued research are highlighted. The result is an overview of the total array reliability problem and of available means of achieving high reliability at minimum cost.

Progress at LAMPF: Clinton P. Anderson Meson Physics Facility. Progress report, January-June 1981

DOE Office of Scientific and Technical Information (OSTI.GOV)

Allred, J.C.

1981-09-01

Progress at LAMPF is the semiannual progress report of the MP Division of the Los Alamos National Laboratory. The report includes brief reports on research done at LAMPF by researchers from other institutions and Los Alamos divisions.

Laser Ranging to the Moon: How Evolving Technology Enables New Science

NASA Astrophysics Data System (ADS)

Faller, James

2010-03-01

Technological advances have long been the enabler of scientific progress. The invention of the laser is a prime example of this symbiotic relationship between technical progress and scientific advances. The laser, which today is omnipresent in each of our lives, made its first appearance during the time that I was a graduate student in Professor Dicke's group at Princeton. A major change occurring during that time period was that technology was transforming the study of gravitational physics from just a theoretical subject into also an experimental subject where one could hope to measure things using by-then-available laboratory technologies and techniques. During this same time, the idea for the lunar laser ranging experiment was born. The history and accomplishments of this experiment--a still ongoing experiment which is one of the real scientific triumphs of NASA's Apollo program--will be given.

Research in cosmic and gamma ray astrophysics: Cosmic physics portion

NASA Technical Reports Server (NTRS)

Stone, Edward C.; Mewaldt, Richard A.; Schindler, Stephen

1993-01-01

Research in particle astrophysics at the Space Radiation Laboratory (SRL) of the California Institute of Technology is supported under NASA Grant NAGW-1919. A three-year proposal for continuation of support was submitted a year ago and put into effect 1 October 1992. This report is the combined progress report and continuation application called for under the Federal Demonstration Project. Gamma-ray Astrophysics at SRL is separately supported under NAGW-1919 and will be separately summarized and proposed. This report will document progress and plans for our particle spectroscopy activities and for related data analysis, calibration, and community service activities. A bibliography and a budget will be attached as appendices. The Caltech SRL research program includes a heavy emphasis on elemental and isotopic spectroscopy of energetic particles in the cosmic radiation; in solar, interplanetary, and anomalous 'cosmic' radiation; and in planetary magnetospheres as discussed.

Progress in the blood supply of Afghanistan.

PubMed

Riley, William J; McCullough, Terri Konstenius; Rhamani, Ahmad Masoud; McCullough, Jeffrey

2017-07-01

The blood supply system in Afghanistan was badly damaged by years of conflict. In 2009, the Afghanistan National Blood Safety and Transfusion Service (ANBSTS) was established. For 6 years, we collaborated to assist with policy and infrastructure development; blood bank operations; blood collection, testing, and component production; transfusion practices; and training of technicians, nurses, midwives, and physicians. Policies were established, infrastructure was strengthened, and capable staff was acquired and trained. Standard operating procedures were developed, testing was improved, and quality systems were established. Thirty trainings were held for blood center staff. Four additional formal trainings were held for 39 physicians, 36 nurses and/or midwives, and 38 laboratory technicians. During 5 years of this project, blood collection increased by 40%. The ANBSTS has made impressive progress developing infrastructure, personnel, procedures, quality systems, and training programs and increasing blood collection. Knowledge of transfusion medicine was improved through structured training. © 2017 AABB.

A modeling analysis program for the JPL table mountain Io sodium cloud

NASA Technical Reports Server (NTRS)

Smyth, W. H.; Goldberg, B. A.

1985-01-01

Progress and achievements in the first year are discussed in three main areas: (1) review and assessment of the massive JPL Table Mountain Io sodium cloud data set, (2) formulation and execution of a plan to perform further processing of this data set, and (3) initiation of modeling activities. The complete 1976-79 and 1981 data sets are reviewed. Particular emphasis is placed on the superior 1981 Region B/C images which provide a rich base of information for studying the structure and escape of gases from Io as well as possible east-west and magnetic longitudinal asymmetries in the plasma torus. A data processing plan is developed and is undertaken by the Multimission Image Processing Laboratory of JPL for the purpose of providing a more refined and complete data set for our modeling studies in the second year. Modeling priorities are formulated and initial progress in achieving these goals is reported.

The effectiveness of Robot-Assisted Gait Training versus conventional therapy on mobility in severely disabled progressIve MultiplE sclerosis patients (RAGTIME): study protocol for a randomized controlled trial.

PubMed

Straudi, Sofia; Manfredini, Fabio; Lamberti, Nicola; Zamboni, Paolo; Bernardi, Francesco; Marchetti, Giovanna; Pinton, Paolo; Bonora, Massimo; Secchiero, Paola; Tisato, Veronica; Volpato, Stefano; Basaglia, Nino

2017-02-27

Gait and mobility impairments affect the quality of life (QoL) of patients with progressive multiple sclerosis (MS). Robot-assisted gait training (RAGT) is an effective rehabilitative treatment but evidence of its superiority compared to other options is lacking. Furthermore, the response to rehabilitation is multidimensional, person-specific and possibly involves functional reorganization processes. The aims of this study are: (1) to test the effectiveness on gait speed, mobility, balance, fatigue and QoL of RAGT compared to conventional therapy (CT) in progressive MS and (2) to explore changes of clinical and circulating biomarkers of neural plasticity. This will be a parallel-group, randomized controlled trial design with the assessor blinded to the group allocation of participants. Ninety-eight (49 per arm) progressive MS patients (EDSS scale 6-7) will be randomly assigned to receive twelve 2-h training sessions over a 4-week period (three sessions/week) of either: (1) RAGT intervention on a robotic-driven gait orthosis (Lokomat, Hocoma, Switzerland). The training parameters (torque of the knee and hip drives, treadmill speed, body weight support) are set during the first session and progressively adjusted during training progression or (2) individual conventional physiotherapy focusing on over-ground walking training performed with the habitual walking device. The same assessors will perform outcome measurements at four time points: baseline (before the first intervention session); intermediate (after six training sessions); end of treatment (after the completion of 12 sessions); and follow-up (after 3 months from the end of the training program). The primary outcome is gait speed, assessed by the Timed 25-Foot Walk Test. We will also assess walking endurance, balance, depression, fatigue and QoL as well as instrumental laboratory markers (muscle metabolism, cerebral venous hemodynamics, cortical activation) and circulating laboratory markers (rare circulating cell populations pro and anti-inflammatory cytokines/chemokines, growth factors, neurotrophic factors, coagulation factors, other plasma proteins suggested by transcriptomic analysis and metabolic parameters). The RAGT training is expected to improve mobility compared to the active control intervention in progressive MS. Unique to this study is the analysis of various potential markers of plasticity in relation with clinical outcomes. ClinicalTrials.gov, identifier: NCT02421731 . Registered on 19 January 2015 (retrospectively registered).

United States Air Force Summer Research Program -- 1993. Volume 8. Phillips Laboratory

DTIC Science & Technology

1993-12-01

Research Program Phillips Laboratory Kirtland Air Force Base Albuquerque. New Mexico Sponsored by...Best Available Copy UNITED STATES AIR FORCE SUMMER RESEARCH PROGRAM -- 1993 SUMMER RESEARCH PROGRAM FINAL REPORTS VOLUME 8 PHILLIPS LABORATORY ...Alabama Box 870344 Tuscaloosa, AL 35487-0344 Final Report for: Graduate Student Research Program Phillips Laboratory , Hanscom AFB Sponsored by: Air

FY2016 Propulsion Materials Annual Progress Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

The Propulsion Materials Program actively supports the energy security and reduction of greenhouse emissions goals of VTO by investigating and identifying the materials properties that are most essential for continued development of cost-effective, highly efficient, and environmentally friendly next-generation heavy and light-duty powertrains. The technical approaches available to enhance propulsion systems focus on improvements in both vehicle efficiency and fuel substitution, both of which must overcome the performance limitations of the materials currently in use. Propulsion Materials Program activities work with national laboratories, industry experts, and VTO powertrain systems (e.g., Advanced Combustion Engines and Fuels) teams to develop strategies thatmore » overcome materials limitations in future powertrain performance. The technical maturity of the portfolio of funded projects ranges from basic science to subsystem prototype validation. Projects within a Propulsion Materials Program activity address materials concerns that directly impact critical technology barriers within each of the above programs, including barriers that impact fuel efficiency, thermal management, emissions reduction, improved reliability, and reduced manufacturing costs. The program engages only the barriers that result from material property limitations and represent fundamental, high-risk materials issues.« less

Francis Bitter National Laboratory quarterly progress report, July 1, 1972--September 30, 1972

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1972-10-31

Reports on research projects at Francis Bitter National Magnet Laboratory are presented on 19 different topics including the following: far infrared magneto-optics; quantum optics; soft x-rays and laser-produced plasmas; magneto-optical theory; magnetism and superconductivity; Mossbauer effect studies; superconducting thin films; amorphous semiconductors and superconductivity; nuclear magnetic resonance of biomolecules; low magnetic fields; superconducting medical magnet; magnetically guided catheters; magnetic separation; high current switching; development of guided electromagnetic flight; Alcator; high voltage discharges in cryocables; and low temperature thermometry in high magnetic fields. The Magnet Research and Technology Program and reports of visiting scientists are also included in this report. Reportsmore » on some research not supported by NSF are included, and the supporting agencies are indicated. A list of publications and speeches presented at meetings during the quarter covered by this report are included in an appendix.« less

US Army Aeromedical Research Laboratory Annual Progress Report, FY 1981.

DTIC Science & Technology

1981-10-01

PROGRAM ELEMENT. PROJECT. TASK US Army Aeromedical Research Laboratory AREA 6 WORK UNIT NUMBERS PO Box 577 Fort Rucker, Alabama 36362 Listed on each DD...d J F I’ 0 l I I I I ;11 11 it Ili di fi li I t t o tim!L’ 151 niii tt 11 ,0 lo 1’ I I J rt 1,( K 1 soo m~r mOo I r I) o r t AIi t tO hi1t Lle I’I tu...I I, I ’ 11 t hit f:1iU :IJ . ] i ;)1T11C 1t 11i1 hs boo par kcW ind ulitac~u ho 1,1-i c " t I a It Cs rt I U I o v’! : a rd anId oxo c t cc ha at in

Visitor's Guide | Frederick National Laboratory for Cancer Research

Cancer.gov

The Frederick National Laboratory for Cancer Research headquarters are located at the Advanced Technology and Research Facility (ATRF), located at 8560 Progress Drive, Frederick Maryland. Additional offices and laboratories are locatedon the NC

Materials sciences programs: Fiscal year 1994

NASA Astrophysics Data System (ADS)

1995-04-01

The Division of Materials Sciences is located within the DOE in the Office of Basic Energy Sciences. The Division of Materials Sciences is responsible for basic research and research facilities in strategic materials science topics of critical importance to the mission of the Department and its Strategic Plan. Materials Science is an enabling technology. The performance parameters, economics, environmental acceptability and safety of all energy generation, conversion, transmission and conservation technologies are limited by the properties and behavior of materials. The Materials Sciences programs develop scientific understanding of the synergistic relationship amongst the synthesis, processing, structure, properties, behavior, performance and other characteristics of materials. Emphasis is placed on the development of the capability to discover technologically, economically, and environmentally desirable new materials and processes, and the instruments and national user facilities necessary for achieving such progress. Materials Sciences sub-fields include physical metallurgy, ceramics, polymers, solid state and condensed matter physics, materials chemistry, surface science and related disciplines where the emphasis is on the science of materials. This report includes program descriptions for 458 research programs including 216 at 14 DOE National Laboratories, 242 research grants (233 for universities), and 9 Small Business Innovation Research (SBIR) Grants. The report is divided into eight sections. Section A contains all Laboratory projects, Section B has all contract research projects, Section C has projects funded under the SBIR Program, Section D describes the Center of Excellence for the Synthesis and Processing of Advanced Materials and E has information on major user facilities. F contains descriptions of other user facilities; G, a summary of funding levels; and H, indices characterizing research projects.

Materials sciences programs, fiscal year 1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-04-01

The Division of Materials Sciences is located within the DOE in the Office of Basic Energy Sciences. The Division of Materials Sciences is responsible for basic research and research facilities in strategic materials science topics of critical importance to the mission of the Department and its Strategic Plan. Materials Science is an enabling technology. The performance parameters, economics, environmental acceptability and safety of all energy generation, conversion, transmission and conservation technologies are limited by the properties and behavior of materials. The Materials Sciences programs develop scientific understanding of the synergistic relationship amongst the synthesis, processing, structure, properties, behavior, performance andmore » other characteristics of materials. Emphasis is placed on the development of the capability to discover technologically, economically, and environmentally desirable new materials and processes, and the instruments and national user facilities necessary for achieving such progress. Materials Sciences sub-fields include physical metallurgy, ceramics, polymers, solid state and condensed matter physics, materials chemistry, surface science and related disciplines where the emphasis is on the science of materials. This report includes program descriptions for 458 research programs including 216 at 14 DOE National Laboratories, 242 research grants (233 for universities), and 9 Small Business Innovation Research (SBIR) Grants. The report is divided into eight sections. Section A contains all Laboratory projects, Section B has all contract research projects, Section C has projects funded under the SBIR Program, Section D describes the Center of Excellence for the Synthesis and Processing of Advanced Materials and E has information on major user facilities. F contains descriptions of other user facilities; G, a summary of funding levels; and H, indices characterizing research projects.« less

Development of a quality assurance program for ionizing radiation secondary calibration laboratories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heaton, H.T. II; Taylor, A.R. Jr.

For calibration laboratories, routine calibrations of instruments meeting stated accuracy goals are important. One method of achieving the accuracy goals is to establish and follow a quality assurance program designed to monitor all aspects of the calibration program and to provide the appropriate feedback mechanism if adjustments are needed. In the United States there are a number of organizations with laboratory accreditation programs. All existing accreditation programs require that the laboratory implement a quality assurance program with essentially the same elements in all of these programs. Collectively, these elements have been designated as a Measurement Quality Assurance (MQA) program. Thismore » paper will briefly discuss the interrelationship of the elements of an MQA program. Using the Center for Devices and Radiological Health (CDRH) X-ray Calibration Laboratory (XCL) as an example, it will focus on setting up a quality control program for the equipment in a Secondary Calibration Laboratory.« less

Launch Conditions Might Affect the Formation of Blood Vessel in the Quail Chorioallantoic Membrane

NASA Technical Reports Server (NTRS)

Henry, M. K.; Unsworth, B. R.; Sychev, B. R.; Guryeva, T. S.; Dadasheva, O. A.; Piert, S. J.; Lagel, K. E.; Dubrovin, L. C.; Jahns, G. C.; Boda, K.;

Laboratory Directed Research and Development Program FY 2006 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sjoreen, Terrence P

2007-04-01

The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the US Departmental of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, 'Laboratory Directed Research and Development' (April 19, 2006), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2006. The associated FY 2006 ORNL LDRD Self-Assessment (ORNL/PPA-2007/2) provides financial data about themore » FY 2006 projects and an internal evaluation of the program's management process.« less

The Biochemistry of the Muscle Contraction Process: An Undergraduate Laboratory Experiment Using Viscosity to Follow the Progress of a Reaction.

ERIC Educational Resources Information Center

Belliveau, James F.; And Others

1981-01-01

Describes an undergraduate laboratory experiment using viscosity to follow the progress of the contractile process in muscles. This simple, short experiment illustrates the action of ATP as the source of energy in the contractile process and the catalytic effect of calcium ions as a control in the energy producing process. (CS)

Muscle activity of leg muscles during unipedal stance on therapy devices with different stability properties.

PubMed

Wolburg, Thomas; Rapp, Walter; Rieger, Jochen; Horstmann, Thomas

2016-01-01

To test the hypotheses that less stable therapy devices require greater muscle activity and that lower leg muscles will have greater increases in muscle activity with less stable therapy devices than upper leg muscles. Cross-sectional laboratory study. Laboratory setting. Twenty-five healthy subjects. Electromyographic activity of four lower (gastrocnemius medialis, soleus, tibialis anterior, peroneus longus) and four upper leg muscles (vastus medialis and lateralis, biceps femoris, semitendinosus) during unipedal quiet barefoot stance on the dominant leg on a flat rigid surface and on five therapy devices with varying stability properties. Muscle activity during unipedal stance differed significantly between therapy devices (P < 0.001). The order from lowest to highest relative muscle activity matched the order from most to least stable therapy device. There was no significant interaction between muscle location (lower versus upper leg) and therapy device (P = 0.985). Magnitudes of additional relative muscle activity for the respective therapy devices differed substantially among lower extremity muscles. The therapy devices offer a progressive increase in training intensity, and thus may be useful for incremental training programs in physiotherapeutic practice and sports training programs. Copyright © 2015 Elsevier Ltd. All rights reserved.

Neutrinos and dark matter in the Black Hills

NASA Astrophysics Data System (ADS)

McMahan Norris, Margaret; Sayler, Bentley

2010-02-01

Where in the U.S. could you walk into a hardware store and be asked about neutrinos? It happens regularly in the Black Hills of South Dakota, where preliminary design is in progress for the Deep Underground Science and Engineering Laboratory (DUSEL), a planned NSF Major Research Experimental Facility Construction (MREFC) initiative to be located at the former Homestake gold mine in Lead, SD. DUSEL has physicists buzzing too, as the particle, astro-, and nuclear physics communities have all identified the need for a new laboratory deep beneath the Earth's surface to address some of the most compelling, transformational science at the frontiers of their disciplines. Elusive particles such as neutrinos and WIMPS (a possible candidate for dark matter) -- though they spark the imagination - are equally elusive when trying to explain to students and the public. That will be the task of the Sanford Center for Science Education, planned to be the education arm of DUSEL. Early prototypes of future programs at the education center are now under development, ranging from professional development for teachers to classroom tours to working with American Indian educators. These programs, which are building capacity for the future education center, will be discussed. )

Clinical Pharmacy Education in Japan: Using Simulated Patients in Laboratory-Based Communication-Skills Training before Clinical Practice.

PubMed

Kubota, Rie; Shibuya, Kiyoshi; Tanaka, Yoichi; Aoki, Manahito; Shiomi, Megumi; Ando, Wataru; Otori, Katsuya; Komiyama, Takako

2018-06-01

The Japanese pharmaceutical curriculum was extended from four to six years in 2006. Students now receive practical communication-skills training in their fourth year, before progressing to train in hospital and community pharmacies in their fifth year. Kitasato University School of Pharmacy, Tokyo, had established a program to meet these aims before the 2006 guidance. In the present study, we discuss and evaluate the features of this communication-skills training program. This study enrolled 242 fourth-year pharmacy students at Kitasato University. Students filled out a questionnaire survey after completing the laboratory element of their undergraduate education. As part of training, students were asked to obtain patient data from a model medical chart, before performing simulated patient interviews covering hospital admission and patient counseling. These simulations were repeated in a small group, and feedback was provided to students by both the simulated patient and the faculty after each presentation. It was found that students were able to develop their communication skills through this approach. Thus, an effective system of gradual and continuous training has been developed, which allows students to acquire clinical and practical communication skills.

Development of a Dual-Laser Digital Holography Diagnostic for Surface Characterization at ORNL

NASA Astrophysics Data System (ADS)

Sawyer, J. C.; Biewer, T. M.; Thomas, C. E.; Zhang, Z.

2017-10-01

The Fusion and Materials for Nuclear Systems Division (FMNSD) at Oak Ridge National Laboratory (ORNL), in collaboration with The University of Tennessee, Knoxville and Third Dimension Technologies (TDT), presents continuing progress towards the development of a dual-laser digital holography (DH) technique for 3D imaging of plasma facing component (PFC) surfaces in real time. This update includes results from an ``on the bench'' single-laser DH demonstration. The dual-laser approach utilizes two CO2 lasers tuned to neighboring molecular CO2 lines to extend the 2 π ambiguity of holographic interferograms to 5 mm from the 10 μm wavelength. Reconstruction of the interferogram allows for measurement of changes in surface topology at rates of 2 mm/s. This status of a dual-laser DH system ``on the bench,'' demonstration and implementation on the Proto-MPEX device will be presented. This work was supported by The University of Tennessee JDRD program and the US. D.O.E. contract DE-AC05-00OR22725. Research sponsored by the Laboratory Directed Research and Development Program of ORNL, managed by UT Battelle, LLC, for the U.S. D.O.E.

A Deep Underground Science and Engineering Laboratory (DUSEL) at Kimballton

NASA Astrophysics Data System (ADS)

Vogelaar, R. Bruce

2004-11-01

The National Academy of Science, as well as several long-range plans from the physics communities, have endorsed the need to create a large, multi-disciplinary underground laboratory in the US. Several potential sites have been identified, and the National Science Foundation has begun a solicitation process to help formulate the science program as well as to identify and develop candidate sites. The only site on the East Coast is at Kimballton, near Blacksburg, in western Virginia. Of all the sites, it is the only one located in sedimentary rocks. This makes it an IDEAL and unique location for both physics, geoscience, and engineering studies. Kimballton is also only half an hour from Virginia Tech, the largest university in the state of Virginia. A multi-institution group has been developing this possibility, and will be competing on the national scale to have DUSEL located at Kimballton. One of the assets of this location is a large limestone mine, already at a depth of 2300 ft (1850 mwe), with true drive-in access and extremely large caverns. The DUSEL facility at this location will try to take advantage of the existing infrastructure, while at the same time develop complementary and adjacent facilities down to 7000 ft (6000 mwe) to allow independent operation of the future facility. Since 2003, Virginia Tech and the Naval Research Laboratory have been working to also develop a general low-level facility at this location. The initial program is to help develop extremely low-background germanium and gas proportional counters, and a single super-module of the Low-Energy Neutrino Spectroscopy (LENS) detector -- designed to measure the real-time low-energy neutrino spectrum from the Sun, including the pp-flux. Progress in this program (including seismic imaging), and the proposed overall extensive science program (Phys, Geo, Eng, Bio) which can be addressed at Kimballton will be presented. For further information, see our webpage http://www.phys.vt.edu/ kimballton/ Clearly, if such a national facility were located in the south-east it would be a tremendous resource to regional universities and laboratories. New partners and collaborators are very welcome.

Postdoctoral Fellow | Center for Cancer Research

Cancer.gov

A postdoctoral training position in translational cancer biology is currently available in the Laboratory of Genitourinary Cancer Pathogenesis (LGCP) of the National Cancer Institute (NCI). The position is located in the laboratory of David VanderWeele M.D., Ph.D., whose research group uses in vitro and in vivo functional studies and pathology specimens and next-generation sequencing data to identify and target drivers of prostate cancer progression. The laboratory is interested in characterizing clinically significant, potentially lethal prostate cancer. We are specifically interested in molecular alterations that drive progression of subclones to dominance development of metastatic disease and characterizing therapeutic vulnerabilities. Current work is aimed at using xenograft and organoid models to further characterize the role of putative drivers of progression, and to develop ways to target these alterations.

TTP AL921102: An integrated geophysics program for non-intrusive characterization of mixed-waste landfill sites. FY 1992 year-end progress report: Volume 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hasbrouck, J.C.

1992-11-01

Chem-Nuclear Geotech, Inc. (Geotech), operating contractor for the US Department of Energy Grand Junction Projects Office, is conducting the Integrated Geophysics Program for Non-Intrusive Characterization of Mixed-Waste Landfill Sites (Technical Task Plan [TTP] AL921102). The TTP is part of the Mixed-Waste Landfill Integrated Demonstration (MWLID). The objective of this task was to demonstrate that an integrated program of surface geophysics can be used to effectively and nonintrusively characterize n-mixed-waste landfill sites. To accomplish this objective, integrated field demonstrations were conducted over two previously identified areas of interest (designated Areas A and B) within the MWLID test site at the Chemicalmore » Waste Landfill (CWL), Technical Area 3, at the Sandia National Laboratories, Albuquerque, New Mexico (Figures 1 and 2). Area A was centered roughly around the Chromic Acid and Organics Pits in the southeast-central portion of the landfill and Area B was centered around the ``60`s Pits`` area in the northeast-central portion of the landfill. Pit locations were known in Area A and suspected in Area B. This progress report describes the geophysical surveys conducted by Geotech and presents preliminary displays and analyses. Volume 2 of this report contains the raw data for all the surveys conducted by Geotech for this TTP.« less

United States Air Force Summer Research Program -- 1992 High School Apprenticeship Program (HSAP) Reports. Volume 13. Phillips Laboratory

DTIC Science & Technology

1992-01-01

Research Program Phillips Laboratory I4oJ A*6Iv4 Sponsored by: Air Force Office of Scientific Research Kirtland Air ...UNITED STATES AIR FORCE SUMMER RESEARCH PROGki"A -- 1992 HIGH SCHOOL APPRENTICESHIP PROGRAM (HSAP) REPORTS VOLUME 13 (t PHILLIPS LABORATORY . RESEARCH ...Arlington High School Final Report for: Summer Research Program Geophysics Directorate Phillips Laboratory

Physics Division progress report, January 1, 1984-September 30, 1986

DOE Office of Scientific and Technical Information (OSTI.GOV)

Keller, W.E.

1987-10-01

This report provides brief accounts of significant progress in development activities and research results achieved by Physics Division personnel during the period January 1, 1984, through September 31, 1986. These efforts are representative of the three main areas of experimental research and development in which the Physics Division serves Los Alamos National Laboratory's and the Nation's needs in defense and basic sciences: (1) defense physics, including the development of diagnostic methods for weapons tests, weapon-related high-energy-density physics, and programs supporting the Strategic Defense Initiative; (2) laser physics and applications, especially to high-density plasmas; and (3) fundamental research in nuclear andmore » particle physics, condensed-matter physics, and biophysics. Throughout the report, emphasis is placed on the design, construction, and application of a variety of advanced, often unique, instruments and instrument systems that maintain the Division's position at the leading edge of research and development in the specific fields germane to its mission. A sampling of experimental systems of particular interest would include the relativistic electron-beam accelerator and its applications to high-energy-density plasmas; pulsed-power facilities; directed energy weapon devices such as free-electron lasers and neutral-particle-beam accelerators; high-intensity ultraviolet and x-ray beam lines at the National Synchrotron Light Source (at Brookhaven National Laboratory); the Aurora KrF ultraviolet laser system for projected use as an inertial fusion driver; antiproton physics facility at CERN; and several beam developments at the Los Alamos Meson Physics Facility for studying nuclear, condensed-matter, and biological physics, highlighted by progress in establishing the Los Alamos Neutron Scattering Center.« less

Student perceptions of independent versus facilitated small group learning approaches to compressed medical anatomy education.

PubMed

Whelan, Alexander; Leddy, John J; Mindra, Sean; Matthew Hughes, J D; El-Bialy, Safaa; Ramnanan, Christopher J

2016-01-01

The purpose of this study was to compare student perceptions regarding two, small group learning approaches to compressed (46.5 prosection-based laboratory hours), integrated anatomy education at the University of Ottawa medical program. In the facilitated active learning (FAL) approach, tutors engage students and are expected to enable and balance both active learning and progression through laboratory objectives. In contrast, the emphasized independent learning (EIL) approach stresses elements from the "flipped classroom" educational model: prelaboratory preparation, independent laboratory learning, and limited tutor involvement. Quantitative (Likert-style questions) and qualitative data (independent thematic analysis of open-ended commentary) from a survey of students who had completed the preclerkship curriculum identified strengths from the EIL (promoting student collaboration and communication) and FAL (successful progression through objectives) approaches. However, EIL led to student frustration related to a lack of direction and impaired completion of objectives, whereas active learning opportunities in FAL were highly variable and dependent on tutor teaching style. A "hidden curriculum" was also identified, where students (particularly EIL and clerkship students) commonly compared their compressed anatomy education or their anatomy learning environment with other approaches. Finally, while both groups highly regarded the efficiency of prosection-based learning and expressed value for cadaveric-based learning, student commentary noted that the lack of grade value dedicated to anatomy assessment limited student accountability. This study revealed critical insights into small group learning in compressed anatomy education, including the need to balance student active learning opportunities with appropriate direction and feedback (including assessment). © 2015 American Association of Anatomists.

The Critical Role of the Research Community in Space Weather Planning and Execution

NASA Astrophysics Data System (ADS)

Robinson, Robert M.; Behnke, Richard A.; Moretto, Therese

2018-03-01

The explosion of interest in space weather in the last 25 years has been due to a confluence of efforts all over the globe, motivated by the recognition that events on the Sun and the consequent conditions in interplanetary space and Earth's magnetosphere, ionosphere, and thermosphere can have serious impacts on vital technological systems. The fundamental research conducted at universities, government laboratories, and in the private sector has led to tremendous improvements in the ability to forecast space weather events and predict their impacts on human technology and health. The mobilization of the research community that made this progress possible was the result of a series of actions taken by the National Science Foundation (NSF) to build a national program aimed at space weather. The path forward for space weather is to build on those successes through continued involvement of the research community and support for programs aimed at strengthening basic research and education in academia, the private sector, and government laboratories. Investments in space weather are most effective when applied at the intersection of research and applications. Thus, to achieve the goals set forth originally by the National Space Weather Program, the research community must be fully engaged in the planning, implementation, and execution of space weather activities, currently being coordinated by the Space Weather Operations, Research, and Mitigation Subcommittee under the National Science and Technology Council.

Inter-laboratory assessment of a harmonized zebrafish developmental toxicology assay - progress report on phase I.

PubMed

Gustafson, A-L; Stedman, D B; Ball, J; Hillegass, J M; Flood, A; Zhang, C X; Panzica-Kelly, J; Cao, J; Coburn, A; Enright, B P; Tornesi, M B; Hetheridge, M; Augustine-Rauch, K A

2012-04-01

This report provides a progress update of a consortium effort to develop a harmonized zebrafish developmental toxicity assay. Twenty non-proprietary compounds (10 animal teratogens and 10 animal non-teratogens) were evaluated blinded in 4 laboratories. Zebrafish embryos from pond-derived and cultivated strain wild types were exposed to the test compounds for 5 days and subsequently evaluated for lethality and morphological changes. Each of the testing laboratories achieved similar overall concordance to the animal data (60-70%). Subsequent optimization procedures to improve the overall concordance focused on compound formulation and test concentration adjustments, chorion permeation and number of replicates. These optimized procedures were integrated into a revised protocol and all compounds were retested in one lab using embryos from pond-derived zebrafish and achieved 85% total concordance. To further assess assay performance, a study of additional compounds is currently in progress at two laboratories using embryos from pond-derived and cultivated-strain wild type zebrafish. Copyright © 2011 Elsevier Inc. All rights reserved.

Lawrence Berkeley Laboratory, Institutional Plan FY 1994--1999

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-09-01

The Institutional Plan provides an overview of the Lawrence Berkeley Laboratory mission, strategic plan, scientific initiatives, research programs, environment and safety program plans, educational and technology transfer efforts, human resources, and facilities needs. For FY 1994-1999 the Institutional Plan reflects significant revisions based on the Laboratory`s strategic planning process. The Strategic Plan section identifies long-range conditions that will influence the Laboratory, as well as potential research trends and management implications. The Initiatives section identifies potential new research programs that represent major long-term opportunities for the Laboratory, and the resources required for their implementation. The Scientific and Technical Programs section summarizesmore » current programs and potential changes in research program activity. The Environment, Safety, and Health section describes the management systems and programs underway at the Laboratory to protect the environment, the public, and the employees. The Technology Transfer and Education programs section describes current and planned programs to enhance the nation`s scientific literacy and human infrastructure and to improve economic competitiveness. The Human Resources section identifies LBL staff diversity and development program. The section on Site and Facilities discusses resources required to sustain and improve the physical plant and its equipment. The new section on Information Resources reflects the importance of computing and communication resources to the Laboratory. The Resource Projections are estimates of required budgetary authority for the Laboratory`s ongoing research programs. The Institutional Plan is a management report for integration with the Department of Energy`s strategic planning activities, developed through an annual planning process.« less

Rolling Out Xpert® MTB/RIF for TB Detection in HIV-Infected Populations:An Opportunity for Systems Strengthening.

PubMed

Pathmanathan, Ishani; Date, Anand; Coggin, William L; Nkengasong, John; Piatek, Amy S; Alexander, Heather

2017-03-31

To eliminate preventable deaths, disease and suffering due to tuberculosis (TB), improved diagnostic capacity is critical. The Cepheid Xpert ® MTB/RIF assay is recommended by the World Health Organization as the initial diagnostic test for people with suspected HIV-associated TB. However, despite high expectations, its scale-up in real-world settings has faced challenges, often due to the systems that support it. In this commentary we discuss needs and opportunities for systems strengthening to support widespread scale-up of Xpert ® MTB/RIF as they relate to each step within the TB diagnostic cascade, from finding presumptive patients, to collecting, transporting and testing sputum specimens, to reporting and receiving results, to initiating and monitoring treatment and, ultimately, to ensuring successful and timely treatment and cure. Investments in evidence-based interventions at each step along the cascade and within the system as a whole will augment not only the utility of Xpert ® MTB/RIF, but also the successful implementation of future diagnostic tests. Xpert ® MTB/RIF will only improve patient outcomes if optimally implemented within the context of strong TB programs and systems. Roll-out of this technology to people living with HIV and others in resource-limited settings offers the opportunity to leverage current TB and HIV laboratory, diagnostic and programmatic investments, while also addressing challenges and strengthening coordination between laboratory systems, laboratory-program interfaces, and TB-HIV program interfaces. If successful, the benefits of this tool could extend beyond progress towards global End TB Strategy goals, to improve system-wide capacity for global disease detection and control.

Instrumentation and Controls Division progress report for the period July 1, 1986 to June 30, 1988

DOE Office of Scientific and Technical Information (OSTI.GOV)

Klobe, L.E.

1988-12-01

The Instrumentation and Controls (IandC) Division of Oak Ridge National Laboratory (ORNL) performs basic and applied instrumentation and controls research, development and design engineering, specialized instrument design and fabrication, and maintenance services for instruments, electronics, and computers. The IandC Division is one of the largest RandD organizations of its type among government laboratories, and it exists as the result of an organizational strategy to integrate ORNL's instrumentation and controls-related disciplines into one dedicated functional organization to increase the Laboratory's expertise and capabilities in these rapidly expanding, innovative areas of technology. The Division participates in the programs and projects of ORNLmore » by applying its expertise and capabilities in concert with other divisions to perform basic research and mission-oriented technology development. Many of the Division's RandD tasks that are a part of a larger ORNL program are of sufficient scope that the IandC effort constitutes a separate program element with direct funding and management responsibility within the Division. The activities of IandC include performance of an RandD task in IandC facilities, the participation of from one of many IandC engineers and scientists in a multidisciplinary team working in a specific research area or development project, design and fabrication of a special instrument or instrumentation system, or a few hours of maintenance service. In its support and maintenance work, the role of the IandC Division is to provide a level of expertise appropriate to complete a job successfully at minimum overall cost and time schedule---a role which involves IandC in almost all ORNL activities.« less

Performance and life evaluation of advanced battery technologies for electric vehicle applications

NASA Astrophysics Data System (ADS)

Deluca, W. H.; Gillie, K. R.; Kulaga, J. E.; Smaga, J. A.; Tummillo, A. F.; Webster, C. E.

Advanced battery technology evaluations are performed under simulated electric vehicle (EV) operating conditions at the Argonne Analysis and Diagnostic Laboratory (ADL). The ADL provides a common basis for both performance characterization and life evaluation with unbiased application of tests and analyses. This paper summarizes the performance characterizations and life evaluations conducted in 1990 on nine single cells and fifteen 3- to 360-cell modules that encompass six technologies: (Na/S, Zn/Br, Ni/Fe, Ni/Cd, Ni-metal hydride, and lead-acid). These evaluations were performed for the Department of Energy and Electric Power Research Institute. The results provide battery users, developers, and program managers an interim measure of the progress being made in battery R and D programs, a comparison of battery technologies, and a source of basic data for modelling and continuing R and D.

Summer Research Program (1992). Summer Faculty Research Program (SFRP) Reports. Volume 3. Phillips Laboratory.

DTIC Science & Technology

1992-12-28

Phillips Laboratory Kirtland Air Force Base NM 87117-6008 Sponsored by: Air Force Office of Scientific Research Bolling Air Force Base...Zindel, D.: 1963, Z. Astrophys. 57, 82. 29-13 FINAL REPORT SUMMER FACULTY RESEARCH PROGRAM AT PHILLIPS LABORATORY KIRTLAND AIR FORCE BASE...Program Phillips Laboratory Sponsored by: Air Force Office of Scientific

ORNLs Laboratory Directed Research and Development Program FY 2009 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2010-03-01

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2009. The associated FY 2009 ORNL LDRD Self-Assessment (ORNL/PPA-2010/2) provides financial data andmore » an internal evaluation of the program’s management process.« less

ORNLs Laboratory Directed Research and Development Program FY 2013 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2014-03-01

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the US Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2013. The associated FY 2013 ORNL LDRD Self-Assessment (ORNL/PPA-2014/2) provides financial datamore » and an internal evaluation of the program’s management process.« less

ORNLs Laboratory Directed Research and Development Program FY 2008 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2009-03-01

The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2008. The associated FY 2008 ORNL LDRD Self-Assessment (ORNL/PPA-2008/2) provides financial data and anmore » internal evaluation of the program’s management process.« less

ORNLs Laboratory Directed Research and Development Program FY 2012 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2013-03-01

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the US Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2012. The associated FY 2012 ORNL LDRD Self-Assessment (ORNL/PPA-2012/2) provides financial datamore » and an internal evaluation of the program’s management process.« less

Putting the Laboratory at the Center of Teaching Chemistry

ERIC Educational Resources Information Center

Bopegedera, A. M. R. P.

2011-01-01

This article describes an effective approach to teaching chemistry by bringing the laboratory to the center of teaching, to bring the excitement of discovery to the learning process. The lectures and laboratories are closely integrated to provide a holistic learning experience. The laboratories progress from verification to open-inquiry and…

Clinical pathologist in Korea--training program and its roles in laboratories.

PubMed

Cho, Han-Ik; Lee, Kap No; Park, Jong-Woo; Park, Hyosoon; Kwak, Yun Sik

2002-01-01

A rapid development of practice of laboratory medicine in Korea owes its success to the clinical pathologists (CP), who have played a role of a pathfinder for laboratories. The Korean CP postgraduate education (residency) program is unique in that it is exclusively for laboratory medicine. The training program for clinical pathologists includes diagnostic hematology, diagnostic immunology, clinical microbiology, clinical chemistry, blood bank, diagnostic genetics, informatics and laboratory management. The program has produced a strong group of about 600 laboratory physicians, officially clinical pathologists since 1963. Most of Korean clinical pathologists work as laboratory directors, directors of university hospital laboratories or teaching faculty members in medical schools. The roles of clinical pathologists are laboratory management, interpretation of laboratory test results, clinical consulting services to clinicians and patients, ordering secondary tests after reviews of requested test results and utilization management. The clinical pathologists have developed clinical laboratories to be a main contributor for improved medical practice. During the last 40 years under the turbulent healthcare system, clinical pathologists have significantly contributed to safeguard the laboratory interests. The education program and the role of clinical pathologists are described.

Instantaneous progression reference frame for calculating pelvis rotations: Reliable and anatomically-meaningful results independent of the direction of movement.

PubMed

Kainz, Hans; Lloyd, David G; Walsh, Henry P J; Carty, Christopher P

2016-05-01

In motion analysis, pelvis angles are conventionally calculated as the rotations between the pelvis and laboratory reference frame. This approach assumes that the participant's motion is along the anterior-posterior laboratory reference frame axis. When this assumption is violated interpretation of pelvis angels become problematic. In this paper a new approach for calculating pelvis angles based on the rotations between the pelvis and an instantaneous progression reference frame was introduced. At every time-point, the tangent to the trajectory of the midpoint of the pelvis projected into the horizontal plane of the laboratory reference frame was used to define the anterior-posterior axis of the instantaneous progression reference frame. This new approach combined with the rotation-obliquity-tilt rotation sequence was compared to the conventional approach using the rotation-obliquity-tilt and tilt-obliquity-rotation sequences. Four different movement tasks performed by eight healthy adults were analysed. The instantaneous progression reference frame approach was the only approach that showed reliable and anatomically meaningful results for all analysed movement tasks (mean root-mean-square-differences below 5°, differences in pelvis angles at pre-defined gait events below 10°). Both rotation sequences combined with the conventional approach led to unreliable results as soon as the participant's motion was not along the anterior-posterior laboratory axis (mean root-mean-square-differences up to 30°, differences in pelvis angles at pre-defined gait events up to 45°). The instantaneous progression reference frame approach enables the gait analysis community to analysis pelvis angles for movements that do not follow the anterior-posterior axis of the laboratory reference frame. Copyright © 2016 Elsevier B.V. All rights reserved.

USAF Summer Research Program - 1994 Graduate Student Research Program Final Reports, Volume 8, Phillips Laboratory

DTIC Science & Technology

1994-12-01

Research Group at the Phillips Laboratory at Kirtland Air Force Base...for Summer Graduate Student Research Program Phillips Laboratory Sponsored by: Air Force Office of Scientific Research Boiling Air Force Base, DC...2390 S. York Street Denver, CO 80208-0177 Final Report for: Summer Faculty Research Program Phillips Laboratory Sponsored by: Air Force

USAF Summer Research Program - 1993 Graduate Student Research Program Final Reports, Volume 8, Phillips Laboratory

DTIC Science & Technology

1994-12-01

Research Program Phillips Laboratory Kirtland Air Force Base Albuquerque, New Mexico Sponsored by: Air ...Summer Research Program Phillips Laboratory Sponsored by. Air Force Office of Scientific Research Kirtland Air Force Base, Albuquerque, New Mexico...UNITED STATES AIR FORCE SUMMER RESEARCH PROGRAM -- 1993 SUMMER RESEARCH PROGRAM FINAL REPORTS VOLUME 8

Tomsk Cardiology Center program on lasers in cardiovascular: first results

NASA Astrophysics Data System (ADS)

Gordov, Eugeni P.; Karpov, Rostislav S.; Dudko, Victor A.; Shipulin, Vladimir M.

1994-12-01

Recent progress in biomedical optics resulted in increased activity in this area at a number of different centers. Reported are the first results of the program directed to incorporate at Tomsk Cardiology Center experience gained in Tomsk optical profile research institutions in areas of light-matter interaction, high resolution spectroscopy, laser physics and relevant software and their usage in cardiac therapy, surgery, and diagnostics. To coordinate research work in this direction the special unit-laboratory of laser medicine is organized at the Center. Laboratory activity goes in the following directions: study of spectral properties of vessel walls in norm and atherosclerosis, comparative study of different wavelength laser radiation action on normal and atherosclerotically damaged tissues, novel approach to intravascular imaging, and usage of high sensitive laser spectroscopy for early diagnosis of cardiac diseases. The spectroscopic study of AP and normal tissue is aimed at understanding of differences in internal energy structures and ways of energy migration which are of critical importance for reaching selective laser action on normal and deceased tissues. To compare thermal, mechanical, and photo-chemical variations of tissues caused by laser radiation the XeCl excimer laser with Raman shifting cell and Nd:YAG laser with second, third, and fourth harmonic converters are employed. Fine influence of pulse duration, intensity, and repetition rates on AP removal is considered in laboratory experiments with vessel samples. Preliminary results on theoretical consideration for determination of spectroscopically detectable markers of some cardiac diseases are reported as well.

Hydrology and radionuclide migration program 1987 progress report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marsh, K.V.

1991-03-01

This report presents results from the Lawrence Livermore National Laboratory's participation in the Hydrology and Radionuclide Migration Program at the Nevada Test Site (NTS) during the fiscal year 1987. The report discussed initial data from a new well (UE20n-1) drilled at the Cheshire site; presents a description of a proposed laboratory study of migration of colloids in fractured media; lists data collected during the drilling and initial sampling of UE20n-1; and describes a tentative proposal for work to be performed in FY88 by Lamont-Doherty Geological Observatory. Groundwater sampled from the new well at the Cheshire site contains tritium concentrations comparablemore » to those measured in previous years from locations above and within the Cheshire cavity. This presence of tritium, as well as several other radionuclides, in a well 100 m away from the cavity region indicates transport of radionuclides, validates a proposed model of the flow path, and provides data on rates of groundwater flow. Previous work at the Cheshire site has shown that radionuclides are transported by colloids through fractured media. However, we have no data that can be used for predictive modeling, and existing theories are not applicable. While physical transport mechanisms of sub-micrometer colloids to defined mineral surfaces are well known, predictions based on well-defined conditions differ from experimental observations by orders of magnitude. The U.C. Berkeley group has designed a laboratory experiment to quantify colloid retention and permeability alteration by the retained colloids.« less

Lawrence Livermore National Laboratory FY 2016 Laboratory Directed Research and Development Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Al-Ayat, R.; Gard, E.; Sketchley, J.

The LDRD annual report for FY2016 consists of two parts: The Overview. This section contains a broad description of the LDRD Program, highlights of recent accomplishments and awards, Program statistics, and the LDRD portfolio-management processes. Project Reports. Project reports are submitted by all principal investigators at the end of the fiscal year. The length and depth of the report depends on the project’s lifecycle. For projects that will be continuing the following year, the principal investigator submits a continuing project report, which is a brief update containing descriptions of the goals, scope, motivation, relevance (to DOE/NNSA and Livermore mission areas),more » and technical progress achieved in FY16, as well as a list of selected publications and presentations that resulted from the research. For projects that concluded in FY16, a more detailed final report is provided that is technical in nature and includes the background, objectives, scientific approach, accomplishments, and impacts on the Laboratory missions, as well as a list of publications and presentations that resulted from the research. Project reports are listed under their research topics and organized by year and type, such as exploratory research (ER), feasibility study (FS), laboratory-wide competition (LW), and strategic initiative (SI). Each project is assigned a unique tracking code, an identifier that consists of three elements. The first is the fiscal year in which the project began, the second represents the project type, and the third identifies the serial number of the project for that fiscal year. For example, 16-ERD-100 means the project is an exploratory research project that began in FY16. The three-digit number (100) represents the serial number for the project.« less

Dedicated Laboratory Setup for CO{sub 2} TEA Laser Propulsion Experiments at Rensselaer Polytechnic Institute

DOE Office of Scientific and Technical Information (OSTI.GOV)

Salvador, Israel I.; Kenoyer, David; Myrabo, Leik N.

Laser propulsion research progress has traditionally been hindered by the scarcity of photon sources with desirable characteristics, as well as integrated specialized flow facilities in a dedicated laboratory environment. For TEA CO{sub 2} lasers, the minimal requirements are time-average powers of >100 W), and pulse energies of >10 J pulses with short duration (e.g., 0.1 to 1 {mu}s); furthermore, for the advanced pulsejet engines of interest here, the laser system must simulate pulse repetition frequencies of 1-10 kilohertz or more, at least for two (carefully sequenced) pulses. A well-equipped laser propulsion laboratory should have an arsenal of sensor and diagnosticsmore » tools (such as load cells, thrust stands, moment balances, pressure and heat transfer gages), Tesla-level electromagnet and permanent magnets, flow simulation facilities, and high-speed visualization systems, in addition to other related equipment, such as optics and gas supply systems. In this paper we introduce a cutting-edge Laser Propulsion Laboratory created at Rensselaer Polytechnic Institute, one of the very few in the world to be uniquely set up for beamed energy propulsion (BEP) experiments. The present BEP research program is described, along with the envisioned research strategy that will exploit current and expanded facilities in the near future.« less

Building Stronger State Energy Partnerships with the U.S. Department of Energy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marks, Kate

2011-09-30

This final technical report details the results of total work efforts and progress made from October 2007 – September 2011 under the National Association of State Energy Officials (NASEO) cooperative agreement DE-FC26-07NT43264, Building Stronger State Energy Partnerships with the U.S. Department of Energy. Major topical project areas in this final report include work efforts in the following areas: Energy Assurance and Critical Infrastructure, State and Regional Technical Assistance, Regional Initiative, Regional Coordination and Technical Assistance, and International Activities in China. All required deliverables have been provided to the National Energy Technology Laboratory and DOE program officials.

An artifical corrosion protocol for lap-splices in aircraft skin

NASA Technical Reports Server (NTRS)

Shaw, Bevil J.

1994-01-01

This paper reviews the progress to date to formulate an artificial corrosion protocol for the Tinker AFB C/KC-135 Corrosion Fatigue Round Robin Test Program. The project has provided new test methods to faithfully reproduce the corrosion damage within a lap-splice by accelerated means, the rationale for a new laboratory test environment, and a means for corrosion damage quantification. The approach is pragmatic and the resulting artificial corrosion protocol lays the foundation for future research in the assessment of aerospace alloys. The general means for quantification of corrosion damage has been presented in a form which can be directly applied to structural integrity calculations.

Overview of software development at the parabolic dish test site

NASA Technical Reports Server (NTRS)

Miyazono, C. K.

1985-01-01

The development history of the data acquisition and data analysis software is discussed. The software development occurred between 1978 and 1984 in support of solar energy module testing at the Jet Propulsion Laboratory's Parabolic Dish Test Site, located within Edwards Test Station. The development went through incremental stages, starting with a simple single-user BASIC set of programs, and progressing to the relative complex multi-user FORTRAN system that was used until the termination of the project. Additional software in support of testing is discussed including software in support of a meteorological subsystem and the Test Bed Concentrator Control Console interface. Conclusions and recommendations for further development are discussed.

Severe Accident Sequence Analysis Program: Anticipated transient without scram simulations for Browns Ferry Nuclear Plant Unit 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dallman, R J; Gottula, R C; Holcomb, E E

1987-05-01

An analysis of five anticipated transients without scram (ATWS) was conducted at the Idaho National Engineering Laboratory (INEL). The five detailed deterministic simulations of postulated ATWS sequences were initiated from a main steamline isolation valve (MSIV) closure. The subject of the analysis was the Browns Ferry Nuclear Plant Unit 1, a boiling water reactor (BWR) of the BWR/4 product line with a Mark I containment. The simulations yielded insights to the possible consequences resulting from a MSIV closure ATWS. An evaluation of the effects of plant safety systems and operator actions on accident progression and mitigation is presented.

Laboratory Directed Research and Development FY-15 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pillai, Rekha Sukamar

The Laboratory Directed Research and Development (LDRD) Program at Idaho National Laboratory (INL) reports its status to the U.S. Department of Energy (DOE) by March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the laboratory director broad flexibility for program implementation. LDRD funds are obtained through a charge to all INL programs. This report includes summaries of all INL LDRD research activities supported during Fiscal Year (FY) 2015.

Superfund Contract Laboratory Program

EPA Pesticide Factsheets

The Contract Laboratory Program (CLP) is a national network of EPA personnel, commercial laboratories, and support contractors whose primary mission is to provide data of known and documented quality to the Superfund program.

Zero-gravity cloud physics laboratory: Experiment program definition and preliminary laboratory concept studies

NASA Technical Reports Server (NTRS)

Eaton, L. R.; Greco, E. V.

1973-01-01

The experiment program definition and preliminary laboratory concept studies on the zero G cloud physics laboratory are reported. This program involves the definition and development of an atmospheric cloud physics laboratory and the selection and delineations of a set of candidate experiments that must utilize the unique environment of zero gravity or near zero gravity.

Dental Laboratory Technology Program Guide.

ERIC Educational Resources Information Center

Georgia Univ., Athens. Dept. of Vocational Education.

This program guide contains the standard dental laboratory technology curriculum for both diploma programs and associate degree programs in technical institutes in Georgia. The curriculum encompasses the minimum competencies required for entry-level workers in the dental laboratory technology field. The general information section contains the…

Issues for laboratory outreach programs.

PubMed

1994-01-01

As we saw in the last "As We See It," many hospitals have begun outreach programs. We explored why outreach programs are established, the steps needed to develop a program, and the way to establish the proper business culture in a hospital laboratory for running a successful program. In this issue we identify the new skills laboratory managers need to be outreach managers, show how some programs maintain a competitive advantage, and explain some of the effects health-care reform will have on outreach services, as we ask: What are the requirements and issues involved in operating a successful laboratory outreach program?

CICART Center For Integrated Computation And Analysis Of Reconnection And Turbulence

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bhattacharjee, Amitava

CICART is a partnership between the University of New Hampshire (UNH) and Dartmouth College. CICART addresses two important science needs of the DoE: the basic understanding of magnetic reconnection and turbulence that strongly impacts the performance of fusion plasmas, and the development of new mathematical and computational tools that enable the modeling and control of these phenomena. The principal participants of CICART constitute an interdisciplinary group, drawn from the communities of applied mathematics, astrophysics, computational physics, fluid dynamics, and fusion physics. It is a main premise of CICART that fundamental aspects of magnetic reconnection and turbulence in fusion devices, smaller-scalemore » laboratory experiments, and space and astrophysical plasmas can be viewed from a common perspective, and that progress in understanding in any of these interconnected fields is likely to lead to progress in others. The establishment of CICART has strongly impacted the education and research mission of a new Program in Integrated Applied Mathematics in the College of Engineering and Applied Sciences at UNH by enabling the recruitment of a tenure-track faculty member, supported equally by UNH and CICART, and the establishment of an IBM-UNH Computing Alliance. The proposed areas of research in magnetic reconnection and turbulence in astrophysical, space, and laboratory plasmas include the following topics: (A) Reconnection and secondary instabilities in large high-Lundquist-number plasmas, (B) Particle acceleration in the presence of multiple magnetic islands, (C) Gyrokinetic reconnection: comparison with fluid and particle-in-cell models, (D) Imbalanced turbulence, (E) Ion heating, and (F) Turbulence in laboratory (including fusion-relevant) experiments. These theoretical studies make active use of three high-performance computer simulation codes: (1) The Magnetic Reconnection Code, based on extended two-fluid (or Hall MHD) equations, in an Adaptive Mesh Refinement (AMR) framework, (2) the Particle Simulation Code, a fully electromagnetic 3D Particle-In-Cell (PIC) code that includes a collision operator, and (3) GS2, an Eulerian, electromagnetic, kinetic code that is widely used in the fusion program, and simulates the nonlinear gyrokinetic equations, together with a self-consistent set of Maxwell’s equations.« less

An innovative educational approach to professional development of medical laboratory scientists in Botswana.

PubMed

Magowe, Mabel Km; Ledikwe, Jenny H; Kasvosve, Ishmael; Martin, Robert; Thankane, Kabo; Semo, Bazghina-Werq

2014-01-01

To address the shortage of laboratory scientists in Botswana, an innovative, one-year academic bridging program was initiated at the University of Botswana, to advance diploma-holding laboratory technicians towards becoming laboratory scientists holding Bachelor's degrees. An evaluation was conducted, which described the outcomes of the program and the lessons learned from this novel approach to meeting human resource needs. This was a cross-sectional, mixed-methods evaluation. Qualitative interviews were conducted with graduates of the Bachelor of Science (BSc) Medical Laboratory Sciences (MLS) bridging program, along with the graduates' current supervisors, and key informants who were involved in program development or implementation. The quantitative data collected included a written questionnaire, completed by program graduates, with a retrospective pre-test/post-test survey of graduates' confidence, in terms of key laboratory competencies. The BSc MLS bridging program produced thirty-three laboratory scientists over 3 years. There was a significant increase in confidence among graduates, for specified competencies, after the program (P<0.05). Graduates reported acquiring new skills and, often, accepting new responsibilities at their former workplace, particularly in relationship to leadership and management. Five graduates enrolled in advanced degree programs. Most graduates assumed increased responsibility. However, only two graduates were promoted after completing the training program. The lessons learned include: the importance of stakeholder involvement, the need for data to identify local needs, financial sustainability, catering for the needs of adult learners, and ensuring a technically challenging work environment, conducive to the application of skills learned during training. A strong public health and clinical laboratory system is essential for the rapid detection and control of emerging health threats, and for patient care. However, there is a need to adequately prepare laboratory human resources, to ensure efficient and effective laboratory services. Advancement of laboratory technicians towards becoming laboratory scientists, through a bridging program, can provide the necessary skills within a short time.

LLNL electro-optical mine detection program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderson, C.; Aimonetti, W.; Barth, M.

1994-09-30

Under funding from the Advanced Research Projects Agency (ARPA) and the US Marine Corps (USMC), Lawrence Livermore National Laboratory (LLNL) has directed a program aimed at improving detection capabilities against buried mines and munitions. The program has provided a national test facility for buried mines in arid environments, compiled and distributed an extensive data base of infrared (IR), ground penetrating radar (GPR), and other measurements made at that site, served as a host for other organizations wishing to make measurements, made considerable progress in the use of ground penetrating radar for mine detection, and worked on the difficult problem ofmore » sensor fusion as applied to buried mine detection. While the majority of our effort has been concentrated on the buried mine problem, LLNL has worked with the U.S.M.C. on surface mine problems as well, providing data and analysis to support the COBRA (Coastal Battlefield Reconnaissance and Analysis) program. The original aim of the experimental aspect of the program was the utilization of multiband infrared approaches for the detection of buried mines. Later the work was extended to a multisensor investigation, including sensors other than infrared imagers. After an early series of measurements, it was determined that further progress would require a larger test facility in a natural environment, so the Buried Object Test Facility (BOTF) was constructed at the Nevada Test Site. After extensive testing, with sensors spanning the electromagnetic spectrum from the near ultraviolet to radio frequencies, possible paths for improvement were: improved spatial resolution providing better ground texture discrimination; analysis which involves more complicated spatial queueing and filtering; additional IR bands using imaging spectroscopy; the use of additional sensors other than IR and the use of data fusion techniques with multi-sensor data; and utilizing time dependent observables like temperature.« less

Lawrence Berkeley Laboratory Institutional Plan, FY 1993--1998

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chew, Joseph T.; Stroh, Suzanne C.; Maio, Linda R.

1992-10-01

The FY 1993--1998 Institutional Plan provides an overview of the Lawrence Berkeley Laboratory mission, strategic plan, scientific initiatives, research programs, environment and safety program plans, educational and technology transfer efforts, human resources, and facilities needs. The Strategic Plan section identifies long-range conditions that can influence the Laboratory, potential research trends, and several management implications. The Initiatives section identifies potential new research programs that represent major long-term opportunities for the Laboratory and the resources required for their implementation. The Scientific and Technical Programs section summarizes current programs and potential changes in research program activity. The Environment, Safety, and Health section describesmore » the management systems and programs underway at the Laboratory to protect the environment, the public, and the employees. The Technology Transfer and Education programs section describes current and planned programs to enhance the nation`s scientific literacy and human infrastructure and to improve economic competitiveness. The Human Resources section identifies LBL staff composition and development programs. The section on Site and Facilities discusses resources required to sustain and improve the physical plant and its equipment. The Resource Projections are estimates of required budgetary authority for the Laboratory`s ongoing research programs. The plan is an institutional management report for integration with the Department of Energy`s strategic planning activities that is developed through an annual planning process. The plan identifies technical and administrative directions in the context of the National Energy Strategy and the Department of Energy`s program planning initiatives. Preparation of the plan is coordinated by the Office for Planning and Development from information contributed by the Laboratory`s scientific and support divisions.« less

Building and Rebuilding: The National Public Health Laboratory Systems and Services Before and After the Earthquake and Cholera Epidemic, Haiti, 2009-2015.

PubMed

Jean Louis, Frantz; Buteau, Josiane; Boncy, Jacques; Anselme, Renette; Stanislas, Magalie; Nagel, Mary C; Juin, Stanley; Charles, Macarthur; Burris, Robert; Antoine, Eva; Yang, Chunfu; Kalou, Mireille; Vertefeuille, John; Marston, Barbara J; Lowrance, David W; Deyde, Varough

2017-10-01

Before the 2010 devastating earthquake and cholera outbreak, Haiti's public health laboratory systems were weak and services were limited. There was no national laboratory strategic plan and only minimal coordination across the laboratory network. Laboratory capacity was further weakened by the destruction of over 25 laboratories and testing sites at the departmental and peripheral levels and the loss of life among the laboratory health-care workers. However, since 2010, tremendous progress has been made in building stronger laboratory infrastructure and training a qualified public health laboratory workforce across the country, allowing for decentralization of access to quality-assured services. Major achievements include development and implementation of a national laboratory strategic plan with a formalized and strengthened laboratory network; introduction of automation of testing to ensure better quality of results and diversify the menu of tests to effectively respond to outbreaks; expansion of molecular testing for tuberculosis, human immunodeficiency virus, malaria, diarrheal and respiratory diseases; establishment of laboratory-based surveillance of epidemic-prone diseases; and improvement of the overall quality of testing. Nonetheless, the progress and gains made remain fragile and require the full ownership and continuous investment from the Haitian government to sustain these successes and achievements.

Building and Rebuilding: The National Public Health Laboratory Systems and Services Before and After the Earthquake and Cholera Epidemic, Haiti, 2009–2015

PubMed Central

Jean Louis, Frantz; Buteau, Josiane; Boncy, Jacques; Anselme, Renette; Stanislas, Magalie; Nagel, Mary C.; Juin, Stanley; Charles, Macarthur; Burris, Robert; Antoine, Eva; Yang, Chunfu; Kalou, Mireille; Vertefeuille, John; Marston, Barbara J.; Lowrance, David W.; Deyde, Varough

2017-01-01

Abstract. Before the 2010 devastating earthquake and cholera outbreak, Haiti’s public health laboratory systems were weak and services were limited. There was no national laboratory strategic plan and only minimal coordination across the laboratory network. Laboratory capacity was further weakened by the destruction of over 25 laboratories and testing sites at the departmental and peripheral levels and the loss of life among the laboratory health-care workers. However, since 2010, tremendous progress has been made in building stronger laboratory infrastructure and training a qualified public health laboratory workforce across the country, allowing for decentralization of access to quality-assured services. Major achievements include development and implementation of a national laboratory strategic plan with a formalized and strengthened laboratory network; introduction of automation of testing to ensure better quality of results and diversify the menu of tests to effectively respond to outbreaks; expansion of molecular testing for tuberculosis, human immunodeficiency virus, malaria, diarrheal and respiratory diseases; establishment of laboratory-based surveillance of epidemic-prone diseases; and improvement of the overall quality of testing. Nonetheless, the progress and gains made remain fragile and require the full ownership and continuous investment from the Haitian government to sustain these successes and achievements. PMID:29064354

External Performance Evaluation Program Participation at Fluor Hanford (FH) 222S Lab

DOE Office of Scientific and Technical Information (OSTI.GOV)

CLARK, G.A.

2002-06-01

Fluor Hanford operates the U. S. Department of Energy's (DOE) 2224 Laboratory on the Hanford Site in Southeastern Washington State. 222-S Laboratory recently celebrated its 50th anniversary of providing laboratory services to DOE and DOE contractors on the Hanford Site. The laboratory operated for many years as a production support analytical laboratory, but in the last two decades has supported the Hanford Site cleanup mission. The laboratory performs radioanalytical, inorganic, and organic characterization analyses on highly radioactive liquid and solid tank waste that will eventually be vitrified for long-term storage and or disposal. It is essential that the laboratory reportmore » defensible, highly credible data in its role as a service provider to DOE and DOE contractors. Among other things, the participation in a number of performance evaluation (PE) programs helps to ensure the credibility of the laboratory. The laboratory currently participates in Environmental Resource Associates' Water Pollution (WP) Studies and the DOE Environmental Management Laboratory (EML) Quality Assessment Program (QAP). DOE has mandated participation of the laboratory in the EML QAP. This EML program evaluates the competence of laboratories performing environmental radioanalytical measurements for DOE, and is the most comprehensive and well-established PE program in the DOE community for radiochemical laboratories. Samples are received and analyzed for radionuclides in air filter, soil, vegetation, and water matrices on a semiannual basis. The 222-S Laboratory has performed well in this program over the years as evidenced by the scores in the chart below.« less

[Laboratory medicine in the obligatory postgraduate clinical training system--common clinical training program in the department of laboratory medicine in our prefectural medical university hospital].

PubMed

Okamoto, Yasuyuki

2003-04-01

I propose a postgraduate common clinical training program to be provided by the department of laboratory medicine in our prefectural medical university hospital. The program has three purposes: first, mastering basic laboratory tests; second, developing the skills necessary to accurately interpret laboratory data; third, learning specific techniques in the field of laboratory medicine. For the first purpose, it is important that medical trainees perform testing of their own patients at bedside or in the central clinical laboratory. When testing at the central clinical laboratory, instruction by expert laboratory technicians is helpful. The teaching doctors in the department of laboratory medicine are asked to advise the trainees on the interpretation of data. Consultation will be received via interview or e-mail. In addition, the trainees can participate in various conferences, seminars, and meetings held at the central clinical laboratory. Finally, in order to learn specific techniques in the field of laboratory medicine, several special courses lasting a few months will be prepared. I think this program should be closely linked to the training program in internal medicine.

United States Air Force Summer Research Program -- 1993 Summer Research Program Final Reports. Volume 10. Wright Laboratory

DTIC Science & Technology

1993-01-01

LABORATORIES 5800 Uplander Way Culver City, CA 90230-6608 Program Director, RDL Program Manager , AFOSR Gary Moore Col. Hal Rhoades Program Manager , RDL...Laboratory: PL/RK Aerospace Engineering University of Cinc nati Vol-Page No: 8-10 Cincinnati, OH 45221-0000 Burns, Paul Field: Electrical Engineering as...Laboratory: PL/GP Electrical Engineering Boston University Vol-Page No: a- 5 Boston, MA 2215-0000 GSRP Participant Data Stauffer, Joseph Field: Management MS

Six Strategies for Chemical Waste Minimization in Laboratories.

ERIC Educational Resources Information Center

Matteson, Gary C.; Hadley, Cheri R.

1991-01-01

Guidelines are offered to research administrators for reducing the volume of hazardous laboratory waste. Suggestions include a chemical location inventory, a chemical reuse facility, progressive contracts with chemical suppliers, internal or external chemical recycling mechanisms, a "chemical conservation" campaign, and laboratory fees for…

Customer satisfaction assessment at the Pacific Northwest National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

DN Anderson; ML Sours

2000-03-23

The Pacific Northwest National Laboratory (PNNL) is developing and implementing a customer satisfaction assessment program (CSAP) to assess the quality of research and development provided by the laboratory. This report presents the customer survey component of the PNNL CSAP. The customer survey questionnaire is composed of two major sections: Strategic Value and Project Performance. Both sections contain a set of questions that can be answered with a 5-point Likert scale response. The strategic value section consists of five questions that are designed to determine if a project directly contributes to critical future national needs. The project Performance section consists ofmore » nine questions designed to determine PNNL performance in meeting customer expectations. A statistical model for customer survey data is developed and this report discusses how to analyze the data with this model. The properties of the statistical model can be used to establish a gold standard or performance expectation for the laboratory, and then to assess progress. The gold standard is defined using laboratory management input--answers to four questions, in terms of the information obtained from the customer survey: (1) What should the average Strategic Value be for the laboratory project portfolio? (2) What Strategic Value interval should include most of the projects in the laboratory portfolio? (3) What should average Project Performance be for projects with a Strategic Value of about 2? (4) What should average Project Performance be for projects with a Strategic Value of about 4? To be able to provide meaningful answers to these questions, the PNNL customer survey will need to be fully implemented for several years, thus providing a link between management perceptions of laboratory performance and customer survey data.« less

Strengthening Scientific Verbal Behavior: An Experimental Comparison of Progressively Prompted and Unprompted Programmed Instruction and Prose Tutorials

ERIC Educational Resources Information Center

Davis, Darrel R.; Bostow, Darrel E.; Heimisson, Gudmundur T.

2007-01-01

Web-based software was used to deliver and record the effects of programmed instruction that progressively added formal prompts until attempts were successful, programmed instruction with one attempt, and prose tutorials. Error-contingent progressive prompting took significantly longer than programmed instruction and prose. Both forms of…

USAF Summer Research Program - 1993 Summer Research Extension Program Final Reports, Volume 2, Phillips Laboratory

DTIC Science & Technology

1994-11-01

Research Extension Program Phillips Laboratory Kirtland Air Force Base Sponsored by: Air Force Office of Scientific Research Boiling Air Force Base...Program Phillips Laboratory Sponsored by: Air Force Office of Scientific Research Bolling Air Force Base, Washington, D.C. and Arkansas Tech University...Summer Research Extension Program (SREP) Phillips

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

The past year has been an exciting and productive one for particle physics research at Abilene Christian University. The thrust of our experimental investigations is the study of the nucleon and its excited states. Laboratories where these investigations are presently being conducted are the AGS at Brookhaven, Fermilab and LAMPF. Some analysis of the data for experiments at the Petersburg Nuclear Physics Institute (Gatchina, Russia) is still in progress. Scheduling of activities at different laboratories inevitably leads to occasional conflicts. This likelihood is increased by the present budget uncertainties at the laboratories that make long-term scheduling difficult. For the mostmore » part, the investigators have been able to avoid such conflicts. Only one experiment received beam time in 1994 (E890 at the AGS). The situation for 1995-1996 also appears manageable at this point. E890 and another AGS experiment (E909) will run through May, 1995. El 178 at LAMPF is presently scheduled for August/September 1995. E866 at Fermilab is scheduled to start in Spring/Summer 1996. Undergraduate student involvement has been a key element in this research contract since its inception. Summer students participated at all of the above laboratories in 1994 and the same is planned in 1995. A transition to greater involvement by graduate students will provide cohesiveness to ACU involvement at a given laboratory and full-time on-site involvement in the longer running experiments at FNAL and BNL. Funds to support a full-time graduate student are requested this year. Finally, collaboration by Russian, Croatian and Bosnian scientists has proven to be mutually beneficial to these experimental programs and to the overall programs at the institutions involved. Past support has been augmented by other grants from government agencies and from the Research Council at Abilene Christian University. Additional funds are requested in this renewal to enable more programmatic support for these efforts, so that long-range plans can be made to carry out the experiments and to perform the analysis.« less

Effect of pulsed progressive fluoroscopy on reduction of radiation dose in the cardiac catheterization laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Holmes, D.R. Jr.; Wondrow, M.A.; Gray, J.E.

1990-01-01

The increased application of therapeutic interventional cardiology procedures is associated with increased radiation exposure to physicians, patients and technical personnel. New advances in imaging techniques have the potential for reducing radiation exposure. A progressive scanning video system with a standard vascular phantom has been shown to decrease entrance radiation exposure. The effect of this system on reducing actual radiation exposure to physicians and technicians was assessed from 1984 through 1987. During this time, progressive fluoroscopy was added sequentially to all four adult catheterization laboratories; no changes in shielding procedures were made. During this time, the case load per physician increasedmore » by 63% and the number of percutaneous transluminal coronary angioplasty procedures (a high radiation procedure) increased by 244%. Despite these increases in both case load and higher radiation procedures, the average radiation exposure per physician declined by 37%. During the same time, the radiation exposure for technicians decreased by 35%. Pulsed progressive fluoroscopy is effective for reducing radiation exposure to catheterization laboratory physicians and technical staff.« less

Laboratory and field studies related to the Hydrologic Resources Management Program. Progress report, October 1, 1992--September 30, 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thompson, J.L.; Hawkins, W.L.; Mathews, M.

This report describes research done at Los Alamos in FY 1993 for the Hydrologic Resources Management Program. The US Department of Energy funds this research through two programs at the Nevada Test Site (NTS): defense and groundwater characterization. Los Alamos personnel have continued to study the high-pressure zone created in the aquifer under Yucca Flat. We analyzed data from a hole in this area (U-7cd) and drilled another hole and installed a water monitoring tube at U-4t. We analyzed water from a number of locations on the NTS where we know there are radionuclides in the groundwater and critiqued themore » effectiveness of this monitoring effort. Our program for analyzing postshot debris continued with material from the last nuclear test in September 1992. We supported both the defense program and the groundwater characterization program by analyzing water samples from their wells and by reviewing documents pertaining to future drilling. We helped develop the analytical methodology to be applied to water samples obtained in the environmental restoration and waste management efforts at the NTS. Los Alamos involvement in the Hydrologic Resources Management Program is reflected in the appended list of documents reviewed, presentations given, papers published, and meetings attended.« less

FY2014 Propulsion Materials R&D Annual Progress Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

The Propulsion Materials Program actively supports the energy security and reduction of greenhouse emissions goals of VTO by investigating and identifying the materials properties that are most essential for continued development of cost-effective, highly efficient, and environmentally friendly next-generation heavy and light-duty powertrains. The technical approaches available to enhance propulsion systems focus on improvements in both vehicle efficiency and fuel substitution, both of which must overcome the performance limitations of the materials currently in use. Propulsion Materials Program activities work with national laboratories, industry experts, and VTO powertrain systems (e.g., Advanced Combustion Engines [ACE], Advanced Power Electronics and Electrical Machinesmore » [APEEM], and fuels) teams to develop strategies that overcome materials limitations in future powertrain performance. The technical maturity of the portfolio of funded projects ranges from basic science to subsystem prototype validation. Projects within a Propulsion Materials Program activity address materials concerns that directly impact critical technology barriers within each of the above programs, including barriers that impact fuel efficiency, thermal management, emissions reduction, improved reliability, and reduced manufacturing costs. The program engages only the barriers that result from material property limitations and represent fundamental, high-risk materials issues.« less

Exploring hypothetical learning progressions for the chemistry of nitrogen and nuclear processes

NASA Astrophysics Data System (ADS)

Henry, Deborah McKern

Chemistry is a bridge that connects a number of scientific disciplines. High school students should be able to determine whether scientific information is accurate, how chemistry applies to daily life, and the mechanism by which systems operate (NRC, 2012). This research focuses on describing hypothetical learning progressions for student understanding of the chemical reactions of nitrogen and nuclear processes and examines whether there is consistency in scientific reasoning between these two distinct conceptual areas. The constant comparative method was used to analyze the written products of students including homework, formative and summative tests, laboratory notebooks, reflective journals, written presentations, and discussion board contributions via Edmodo (an online program). The ten participants were 15 and 16 year old students enrolled in a general high school chemistry course. Instruction took place over a ten week period. The learning progression levels ranged from 0 to 4 and were described as missing, novice, intermediate, proficient, and expert. The results were compared to the standards set by the NRC with a lower anchor (expectations for grade 8) and upper anchor (expectations for grade 12). The results indicate that, on average, students were able to reach an intermediate level of understanding for these concepts.

Physics through the 1990s: An overview

NASA Technical Reports Server (NTRS)

1986-01-01

The volume details the interaction of physics and society, and presents a short summary of the progress in the major fields of physics and a summary of the other seven volumes of the Physics through the 1990s series, issues and recommended policy changes are described regarding funding, education, industry participation, small-group university research and large facility programs, government agency programs, and computer database needs. Three supplements report in detail on international issues in physics (the US position in the field, international cooperation and competition-especially on large projects, freedom for scientists, free flow of information, and education of foreign students), the education and supply of physicists (the changes in US physics education, employment and manpower, and demographics of the field), and the organization and support of physics (government, university, and industry research; facilities; national laboratories; and decision making). An executive summary contains recommendations for maintaining excellence in physics. A glossary of scientific terms is appended.

Kaiser Permanente-Sandia National Health Care Model: Phase 1 prototype final report. Part 2 -- Domain analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Edwards, D.; Yoshimura, A.; Butler, D.

This report describes the results of a Cooperative Research and Development Agreement between Sandia National Laboratories and Kaiser Permanente Southern California to develop a prototype computer model of Kaiser Permanente`s health care delivery system. As a discrete event simulation, SimHCO models for each of 100,000 patients the progression of disease, individual resource usage, and patient choices in a competitive environment. SimHCO is implemented in the object-oriented programming language C{sup 2}, stressing reusable knowledge and reusable software components. The versioned implementation of SimHCO showed that the object-oriented framework allows the program to grow in complexity in an incremental way. Furthermore, timingmore » calculations showed that SimHCO runs in a reasonable time on typical workstations, and that a second phase model will scale proportionally and run within the system constraints of contemporary computer technology.« less

Reactivity of young chars via energetic distribution measurements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Calo, J.M.; Lilly, W.D.

1991-01-01

The current project is directed at developing related techniques for the characterization and prediction/correlation of the reactivity of young'' chars to steam and oxygen. Of particular interest is mapping of the reactivity behavior of the resultant chars, as revealed by the energetic heterogeneity of the complexes with char preparation conditions; i.e., heating rate and ultimate temperature. In this first quarterly technical progress report we present the background of the project and the research program for the proposed investigations. The following work was accomplished on the experimental apparatus: a new set of electronics for the UTi quadrupole mass spectrometer head wasmore » purchased and delivered. The Temperature Programmed Desorption (TPD) System was moved to another laboratory and interfaced with the mass spectrometer system. A Polycold{trademark} freon refrigeration system was repaired and interfaced with the vacuum system for the TPD apparatus. It will be used to cool the diffusion pump trap. 60 refs.« less

Current status and recent research achievements in SiC/SiC composites

NASA Astrophysics Data System (ADS)

Katoh, Y.; Snead, L. L.; Henager, C. H.; Nozawa, T.; Hinoki, T.; Iveković, A.; Novak, S.; Gonzalez de Vicente, S. M.

2014-12-01

The silicon carbide fiber-reinforced silicon carbide matrix (SiC/SiC) composite system for fusion applications has seen a continual evolution from development a fundamental understanding of the material system and its behavior in a hostile irradiation environment to the current effort which is directed at a broad-based program of technology maturation program. In essence, over the past few decades this material system has steadily moved from a laboratory curiosity to an engineering material, both for fusion structural applications and other high performance application such as aerospace. This paper outlines the recent international scientific and technological achievements towards the development of SiC/SiC composite material technologies for fusion application and discusses future research directions. It also reviews the materials system in the larger context of progress to maturity as an engineering material for both the larger nuclear community and broader engineering applications.

Time-temperature-stress capabilities of composite materials for advanced supersonic technology application, phase 1

NASA Technical Reports Server (NTRS)

Kerr, J. R.; Haskins, J. F.

1980-01-01

Implementation of metal and resin matrix composites into supersonic vehicle usage is contingent upon accelerating the demonstration of service capacity and design technology. Because of the added material complexity and lack of extensive service data, laboratory replication of the flight service will provide the most rapid method of documenting the airworthiness of advanced composite systems. A program in progress to determine the time temperature stress capabilities of several high temperature composite materials includes thermal aging, environmental aging, fatigue, creep, fracture, and tensile tests as well as real time flight simulation exposure. The program has two parts. The first includes all the material property determinations and aging and simulation exposures up through 10,000 hours. The second continues these tests up to 50,000 cumulative hours. Results are presented of the 10,000 hour phase, which has now been completed.

THE NEXT GENERATION SAFEGUARDS PROFESSIONAL NETWORK: PROGRESS AND NEXT STEPS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhernosek, Alena V; Lynch, Patrick D; Scholz, Melissa A

2011-01-01

President Obama has repeatedly stated that the United States must ensure that the international safeguards regime, as embodied by the International Atomic Energy Agency (IAEA), has 'the authority, information, people, and technology it needs to do its job.' The U.S. Department of Energy (DOE) National Nuclear Security Administration (NNSA) works to implement the President's vision through the Next Generation Safeguards Initiative (NGSI), a program to revitalize the U.S. DOE national laboratories safeguards technology and human capital base so that the United States can more effectively support the IAEA and ensure that it meets current and emerging challenges to the internationalmore » safeguards system. In 2009, in response to the human capital development goals of NGSI, young safeguards professionals within the Global Nuclear Security Technology Division at Oak Ridge National Laboratory launched the Next Generation Safeguards Professional Network (NGSPN). The purpose of this initiative is to establish working relationships and to foster collaboration and communication among the next generation of safeguards leaders. The NGSPN is an organization for, and of, young professionals pursuing careers in nuclear safeguards and nonproliferation - as well as mid-career professionals new to the field - whether working within the U.S. DOE national laboratory complex, U.S. government agencies, academia, or industry or at the IAEA. The NGSPN is actively supported by the NNSA, boasts more than 70 members, maintains a website and newsletter, and has held two national meetings as well as an NGSPN session and panel at the July 2010 Institute of Nuclear Material Management Annual Meeting. This paper discusses the network; its significance, goals and objectives; developments and progress to date; and future plans.« less

Overview of the James Webb Space Telescope observatory

NASA Astrophysics Data System (ADS)

Clampin, Mark

2011-09-01

The James Webb Space Telescope (JWST) is a large aperture, space telescope designed to provide imaging and spectroscopy over the near and mid-infrared from 1.0 μm to 28 μm. JWST is a passively cooled infrared telescope, employing a five layer sunshield to achieve an operating temperature of ~40 K. JWST will be launched to an orbit at L2 aboard an Ariane 5 launcher in 2013. The Goddard Space Flight Center (GSFC) is the lead center for the JWST program and manages the project for NASA. The prime contractor for JWST is Northrop Grumman Aerospace Systems (NGST). JWST is an international partnership with the European Space Agency (ESA), and the Canadian Space Agency (CSA). ESA will contribute the Ariane 5 launch, and a multi-object infrared spectrograph. CSA will contribute the Fine Guidance Sensor (FGS), which includes the Tunable Filter Imager (TFI). A European consortium, in collaboration with the Jet Propulsion Laboratory (JPL), builds the mid-infrared imager (MIRI). In this paper we present an overview of the JWST science program, and discuss recent progress in the development of the observatory. In this paper we will discuss the scientific motivations for JWST, and discuss recent progress in the construction of the observatory, focusing on the telescope and its optics, which have recently completed polishing.

49 CFR 40.107 - Who may inspect laboratories?

Code of Federal Regulations, 2010 CFR

2010-10-01

... DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.107 Who may inspect laboratories? As a...-regulated employer that contracts with the laboratory for drug testing under the DOT drug testing program...

49 CFR 40.107 - Who may inspect laboratories?

Code of Federal Regulations, 2012 CFR

2012-10-01

... DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.107 Who may inspect laboratories? As a...-regulated employer that contracts with the laboratory for drug testing under the DOT drug testing program...

49 CFR 40.107 - Who may inspect laboratories?

Code of Federal Regulations, 2014 CFR

2014-10-01

... DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.107 Who may inspect laboratories? As a...-regulated employer that contracts with the laboratory for drug testing under the DOT drug testing program...

49 CFR 40.107 - Who may inspect laboratories?

Code of Federal Regulations, 2013 CFR

2013-10-01

... DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.107 Who may inspect laboratories? As a...-regulated employer that contracts with the laboratory for drug testing under the DOT drug testing program...

49 CFR 40.107 - Who may inspect laboratories?

Code of Federal Regulations, 2011 CFR

2011-10-01

... DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.107 Who may inspect laboratories? As a...-regulated employer that contracts with the laboratory for drug testing under the DOT drug testing program...

24. CONSTRUCTION PROGRESS VIEW TO NORTHWEST, SHOWING BLOWER BUILDING. INEEL ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

24. CONSTRUCTION PROGRESS VIEW TO NORTHWEST, SHOWING BLOWER BUILDING. INEEL PHOTO NUMBER NRTS-60-4407. - Idaho National Engineering Laboratory, Old Waste Calcining Facility, Scoville, Butte County, ID

Experimental, Theoretical and Computational Studies of Plasma-Based Concepts for Future High Energy Accelerators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Joshi, Chan; Mori, W.

2013-10-21

This is the final report on the DOE grant number DE-FG02-92ER40727 titled, “Experimental, Theoretical and Computational Studies of Plasma-Based Concepts for Future High Energy Accelerators.” During this grant period the UCLA program on Advanced Plasma Based Accelerators, headed by Professor C. Joshi has made many key scientific advances and trained a generation of students, many of whom have stayed in this research field and even started research programs of their own. In this final report however, we will focus on the last three years of the grant and report on the scientific progress made in each of the four tasksmore » listed under this grant. Four tasks are focused on: Plasma Wakefield Accelerator Research at FACET, SLAC National Accelerator Laboratory, In House Research at UCLA’s Neptune and 20 TW Laser Laboratories, Laser-Wakefield Acceleration (LWFA) in Self Guided Regime: Experiments at the Callisto Laser at LLNL, and Theory and Simulations. Major scientific results have been obtained in each of the four tasks described in this report. These have led to publications in the prestigious scientific journals, graduation and continued training of high quality Ph.D. level students and have kept the U.S. at the forefront of plasma-based accelerators research field.« less

Advanced In-Pile Instrumentation for Materials Testing Reactors

NASA Astrophysics Data System (ADS)

Rempe, J. L.; Knudson, D. L.; Daw, J. E.; Unruh, T. C.; Chase, B. M.; Davis, K. L.; Palmer, A. J.; Schley, R. S.

2014-08-01

The U.S. Department of Energy sponsors the Advanced Test Reactor (ATR) National Scientific User Facility (NSUF) program to promote U.S. research in nuclear science and technology. By attracting new research users - universities, laboratories, and industry - the ATR NSUF facilitates basic and applied nuclear research and development, advancing U.S. energy security needs. A key component of the ATR NSUF effort is to design, develop, and deploy new in-pile instrumentation techniques that are capable of providing real-time measurements of key parameters during irradiation. This paper describes the strategy developed by the Idaho National Laboratory (INL) for identifying instrumentation needed for ATR irradiation tests and the program initiated to obtain these sensors. New sensors developed from this effort are identified, and the progress of other development efforts is summarized. As reported in this paper, INL researchers are currently involved in several tasks to deploy real-time length and flux detection sensors, and efforts have been initiated to develop a crack growth test rig. Tasks evaluating `advanced' technologies, such as fiber-optics based length detection and ultrasonic thermometers, are also underway. In addition, specialized sensors for real-time detection of temperature and thermal conductivity are not only being provided to NSUF reactors, but are also being provided to several international test reactors.

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2011. The associated FY 2011 ORNL LDRD Self-Assessment (ORNL/PPA-2012/2) provides financial datamore » and an internal evaluation of the program’s management process.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2010. The associated FY 2010 ORNL LDRD Self-Assessment (ORNL/PPA-2011/2) provides financial datamore » and an internal evaluation of the program’s management process.« less

Emerging paradigms and questions on pro-angiogenic bone marrow-derived myelomonocytic cells.

PubMed

Laurent, Julien; Touvrey, Cédric; Botta, Francesca; Kuonen, François; Ruegg, Curzio

2011-01-01

Cancer-related inflammation has emerged in recent years as a major event contributing to tumor angiogenesis, tumor progression and metastasis formation. Bone marrow-derived and inflammatory cells promote tumor angiogenesis by providing endothelial progenitor cells that differentiate into mature endothelial cells, and by secreting pro-angiogenic factors and remodeling the extracellular matrix to stimulate angiogenesis though paracrine mechanisms. Several bone marrow-derived myelonomocytic cells, including monocytes and macrophages, have been identified and characterized by several laboratories in recent years. While the central role of these cells in promoting tumor angiogenesis, tumor progression and metastasis is nowadays well established, many questions remain open and new ones are emerging. These include the relationship between their phenotype and function, the mechanisms of pro-angiogenic programming, their contribution to resistance to anti-angiogenic treatments and to metastasis and their potential clinical use as biomarkers of angiogenesis and anti-angiogenic therapies. Here, we will review phenotypical and functional aspects of bone marrow-derived myelonomocytic cells and discuss some of the current outstanding questions.

Recent Progress in the Development of a Multi-Layer Green's Function Code for Ion Beam Transport

NASA Technical Reports Server (NTRS)

Tweed, John; Walker, Steven A.; Wilson, John W.; Tripathi, Ram K.

2008-01-01

To meet the challenge of future deep space programs, an accurate and efficient engineering code for analyzing the shielding requirements against high-energy galactic heavy radiation is needed. To address this need, a new Green's function code capable of simulating high charge and energy ions with either laboratory or space boundary conditions is currently under development. The computational model consists of combinations of physical perturbation expansions based on the scales of atomic interaction, multiple scattering, and nuclear reactive processes with use of the Neumann-asymptotic expansions with non-perturbative corrections. The code contains energy loss due to straggling, nuclear attenuation, nuclear fragmentation with energy dispersion and downshifts. Previous reports show that the new code accurately models the transport of ion beams through a single slab of material. Current research efforts are focused on enabling the code to handle multiple layers of material and the present paper reports on progress made towards that end.

Driving Extreme Efficiency to Market

NASA Astrophysics Data System (ADS)

Garbesi, Karina

2014-03-01

The rapid development of extremely energy efficient appliances and equipment is essential to curtail catastrophic climate disruption. This will require the on-going development of products that apply all best-practices and that take advantage of the synergies of hybridization and building integration. Beyond that, it requires the development of new disruptive technologies and concepts. To facilitate these goals, in 2011 the Lawrence Berkeley National Laboratory and the U.S. Department of Energy launched the Max Tech and Beyond Design Competition for Ultra-Low-Energy-Use Appliances and Equipment. Now in its third year, the competition supports faculty-lead student design teams at U.S. universities to develop and test new technology prototypes. This talk describes what the competition and the Max Tech Program are doing to drive such rapid technology progress and to facilitate the entry to the market of successful Max Tech prototypes. The talk also initiates a discussion of physicists' unique role in driving that technology progress faster and farther. Emerging Technologies, Building Technologies Office, U.S. Department of Energy.

Competency assessment in laboratory medicine: Standardization and utility for technical staff assessment and recertification in Saudi Arabia.

PubMed

Nemenqani, Dalal M; Tekian, Ara; Park, Yoon Soo

2017-04-01

The assessment of technical staff members' competency has been a challenge for laboratory workers, to ensure patient safety and high quality services. The aim of this study was to (1) investigate awareness on best ways to assess lab competencies; (2) identify existing institutional methods of competency assessment and how staff perceptions; and (3) gather opinions of respondents about a proposed program for competency assessment in laboratory medicine. A cross-sectional survey was conducted, followed by an interview and discussion with laboratory stakeholders about a proposed competency assessment program that included all the six procedural elements of laboratory personnel competency assessment. An online questionnaire was sent via email to different hospitals in Saudi Arabia through survey monkey. A proposed competency assessment program was circulated via email to laboratory stakeholders who agreed to be enrolled in structured interviews. A total of 47 out of the 168 (25.3%) laboratory workers responded to the emailed survey administered via survey monkey. Among the survey respondents, 16 out of the 47 (34%) participated in the structured interview and the discussion and formed the community of practice group that provided insight and opinion about the proposed competency program. Among stakeholders, 87.2% practiced in accredited laboratories. Over half (52%) of respondents positively rated the proposed program. Results of interviews and discussions revealed suggestions about continuous ongoing assessment, such as the inclusion of laboratory quality management and safety as separate items to be unified for all sections. The proposed competency assessment program overcomes challenges noted in competency assessment and has been positively received by stakeholders. This program will be validated by a group of experts then implemented as part of a core curriculum for laboratory staff, in their assessment, certification, recertification, registration, evaluation and licensure in sample laboratories in Saudi Arabia. The program will be monitored and evaluated during and after implementation for processes and outcomes. Conclusions will be utilized for national competency program. This study represents an important step towards the implementation of a standardized laboratory competence assessment program at a national level.

Development of New Treatments for Prostate Cancer

DOE Office of Scientific and Technical Information (OSTI.GOV)

DiPaola, R. S.; Abate-Shen, C.; Hait, W. N.

2005-02-01

The Dean and Betty Gallo Prostate Cancer Center (GPCC) was established with the goal of eradicating prostate cancer and improving the lives of men at risk for the disease through research, treatment, education and prevention. GPCC was founded in the memory of Dean Gallo, a beloved New Jersey Congressman who died tragically of prostate cancer diagnosed at an advanced stage. GPCC unites a team of outstanding researchers and clinicians who are committed to high-quality basic research, translation of innovative research to the clinic, exceptional patient care, and improving public education and awareness of prostate cancer. GPCC is a center ofmore » excellence of The Cancer Institute of New Jersey, which is the only NCI-designated comprehensive cancer center in the state. GPCC efforts are now integrated well as part of our Prostate Program at CINJ, in which Dr. Robert DiPaola and Dr. Cory Abate-Shen are co-leaders. The Prostate Program unites 19 investigators from 10 academic departments who have broad and complementary expertise in prostate cancer research. The overall goal and unifying theme is to elucidate basic mechanisms of prostate growth and oncogenesis, with the ultimate goal of promoting new and effective strategies for the eradication of prostate cancer. Members' wide range of research interests collectively optimize the chances of providing new insights into normal prostate biology and unraveling the molecular pathophysiology of prostate cancer. Cell culture and powerful animal models developed by program members recapitulate the various stages of prostate cancer progression, including prostatic intraepithelial neoplasia, adenocarcinoma, androgen-independence, invasion and metastases. These models promise to further strengthen an already robust program of investigator-initiated therapeutic clinical trials, including studies adopted by national cooperative groups. Efforts to translate laboratory results into clinical studies of early detection and chemoprevention are underway. The specific goals of this program are: (1) To investigate the molecular mechanisms underlying normal prostate growth and differentiation and elucidate the molecular mechanisms underlying prostate oncogenesis. (2) To build on fundamental knowledge to develop effective therapeutic approaches for the treatment of prostate cancer. (3) To improve the control of prostate cancer through early detection, chemoprevention, and outreach and education. This new disease-based program is structured to improve interdisciplinary interactions and translational results. Already, through the dynamic leadership of Drs. Cory Abate-Shen and Robert DiPaola, new investigators were attracted to the field, new collaborations engendered, and numerous investigator-initiated trials implemented. Progress in GPCC and the program overall has been outstanding. The Center has success in uniting investigators with broad and complementary expertise in prostate cancer research. The overall goal and unifying theme is to elucidate basic mechanisms of prostate growth and oncogenesis, with the ultimate goal of promoting new and effective strategies for the eradication of prostate cancer in patients and populations at risk. Members wide range of research interests collectively optimize the chances of providing new insights into normal prostate biology and unraveling the molecular pathophysiology of prostate cancer. Studies in cell culture and powerful animal models developed recapitulate the various stages of prostate cancer progression, including prostatic intraepithelial neoplasia, adenocarcinoma, androgen-independence, invasion and metastases. These models promise to further strengthen an already robust program of investigator-initiated therapeutic clinical trials, including studies adopted by national cooperative groups. Efforts to translate laboratory results into clinical studies of early detection and chemoprevention are underway.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

King, A.G.

The Pacific Northwest Laboratory (PNL)/Analytical Chemistry Laboratory (ACL) and the Westinghouse Hanford Company (WHC)/Process Analytical Laboratory (PAL) provide analytical support services to various environmental restoration and waste management projects/programs at Hanford. In response to a US Department of Energy -- Richland Field Office (DOE-RL) audit, which questioned the comparability of analytical methods employed at each laboratory, the Sample Exchange/Exchange (SEE) program was initiated. The SEE Program is a selfassessment program designed to compare analytical methods of the PAL and ACL laboratories using sitespecific waste material. The SEE program is managed by a collaborative, the Quality Assurance Triad (Triad). Triad membershipmore » is made up of representatives from the WHC/PAL, PNL/ACL, and WHC Hanford Analytical Services Management (HASM) organizations. The Triad works together to design/evaluate/implement each phase of the SEE Program.« less

ICF Annual Report 1997

DOE Office of Scientific and Technical Information (OSTI.GOV)

Correll, D

The continuing objective of Lawrence Livermore National Laboratory's (LLNL's) Inertial Confinement Fusion (ICF) Program is the demonstration of thermonuclear fusion ignition and energy gain in the laboratory and to support the nuclear weapons program in its use of ICF facilities. The underlying theme of all ICF activities as a science research and development program is the Department of Energy's (DOE's) Defense Programs (DP) science-based Stockpile Stewardship Program (SSP). The mission of the US Inertial Fusion Program is twofold: (1) to address high-energy-density physics issues for the SSP and (2) to develop a laboratory microfusion capability for defense and energy applications.more » In pursuit of this mission, the ICF Program has developed a state-of-the-art capability to investigate high-energy-density physics in the laboratory. The near-term goals pursued by the ICF Program in support of its mission are demonstrating fusion ignition in the laboratory and expanding the Program's capabilities in high-energy-density science. The National Ignition Facility (NIF) project is a cornerstone of this effort.« less

Precise Laboratory Measurement of Line Frequencies Useful to Studies of Star and Planet Formation

NASA Technical Reports Server (NTRS)

Myers, Philip C.; Gottlieb, Carl A.

2005-01-01

In March 2002, we began a program in laboratory spectroscopy to provide accurate molecular line frequencies essential to studies of the motions and abundance in star-forming dense cores and planet-forming circumstellar disks. Summarized here is the progress that has been made in Year 3 of this grant. Work included measurement of 10 successive rotational lines in the ground vibrational state of SiO between 86 and 500 GHz, and two lines near 800 GHz to an accuracy of a few kHz; conducting pilot experiments on molecular ions in collision-free supersonic beams, including HCO+, N2H+, and H2D+; measurement of 22 lines of CN between 113 and 340 GHz; and setting up an experiment that would allow us to refine earlier measurements of the neutral species such as C3H2, CCS, H2CS, and SO by observing the very narrow sub-Doppler (Lamb dip) features in the millimeter-wave spectra of these species.

Investigation of injury/illness data at a nuclear facility. Part II

DOE PAGES

Cournoyer, Michael E.; Garcia, Vincent E.; Sandoval, Arnold N.; ...

2015-07-01

At Los Alamos National Laboratory (LANL), there are several nuclear facilities, accelerator facilities, radiological facilities, explosives sites, moderate- and high-hazard non-nuclear facilities, biosciences laboratory, etc. The Plutonium Science and Manufacturing Directorate (ADPSM) provides special nuclear material research, process development, technology demonstration, and manufacturing capabilities. ADPSM manages the LANL Plutonium Facility. Within the Radiological Control Area at TA-55 (PF-4), chemical and metallurgical operations with plutonium and other hazardous materials are performed. LANL Health and Safety Programs investigate injury and illness data. In this study, statistically significant trends have been identified and compared for LANL, ADPSM, and PF-4 injury/illness cases. A previouslymore » described output metric is used to measures LANL management progress towards meeting its operational safety objectives and goals. Timelines are used to determine trends in Injury/Illness types. Pareto Charts are used to prioritize causal factors. The data generated from analysis of Injury/Illness data have helped identify and reduce the number of corresponding causal factors.« less

Epidemiology of Human Anthrax in China, 1955−2014

PubMed Central

Li, Yu; Yin, Wenwu; Hugh-Jones, Martin; Wang, Liping; Mu, Di; Ren, Xiang; Zeng, Lingjia; Chen, Qiulan; Li, Wei; Wei, Jianchun; Lai, Shengjie; Zhou, Hang

2017-01-01

Using national surveillance data for 120,111 human anthrax cases recorded during 1955−2014, we analyzed the temporal, seasonal, geographic, and demographic distribution of this disease in China. After 1978, incidence decreased until 2013, when it reached a low of 0.014 cases/100,000 population. The case-fatality rate, cumulatively 3.6% during the study period, has also decreased since 1990. Cases occurred throughout the year, peaking in August. Geographic distribution decreased overall from west to east, but the cumulative number of affected counties increased during 2005−2014. The disease has shifted from industrial to agricultural workers; 86.7% of cases occurred in farmers and herdsmen. Most (97.7%) reported cases were the cutaneous form. Although progress has been made in reducing incidence, this study highlights areas that need improvement. Adequate laboratory diagnosis is lacking; only 7.6% of cases received laboratory confirmation. Geographic expansion of the disease indicates that livestock control programs will be essential in eradicating anthrax. PMID:27983489

Epidemiology of Human Anthrax in China, 1955-2014.

PubMed

Li, Yu; Yin, Wenwu; Hugh-Jones, Martin; Wang, Liping; Mu, Di; Ren, Xiang; Zeng, Lingjia; Chen, Qiulan; Li, Wei; Wei, Jianchun; Lai, Shengjie; Zhou, Hang; Yu, Hongjie

2017-01-01

Using national surveillance data for 120,111 human anthrax cases recorded during 1955-2014, we analyzed the temporal, seasonal, geographic, and demographic distribution of this disease in China. After 1978, incidence decreased until 2013, when it reached a low of 0.014 cases/100,000 population. The case-fatality rate, cumulatively 3.6% during the study period, has also decreased since 1990. Cases occurred throughout the year, peaking in August. Geographic distribution decreased overall from west to east, but the cumulative number of affected counties increased during 2005-2014. The disease has shifted from industrial to agricultural workers; 86.7% of cases occurred in farmers and herdsmen. Most (97.7%) reported cases were the cutaneous form. Although progress has been made in reducing incidence, this study highlights areas that need improvement. Adequate laboratory diagnosis is lacking; only 7.6% of cases received laboratory confirmation. Geographic expansion of the disease indicates that livestock control programs will be essential in eradicating anthrax.

Research on International Space Station - Building a Partnership for the Future

NASA Technical Reports Server (NTRS)

Gindl, Heinz; Scheimann, Jens; Shirakawa, Masaki; Suvorov, Vadim; Uri, John J.

2004-01-01

As its name implies, the International Space Station is a platform where the research programs of 16 partner nations are conducted. While each partner pursues its own research priorities, cooperation and coordination of the various national and agency research programs occurs at multiple levels, from strategic through tactical planning to experiment operations. Since 2000, a significant number of experiments have been carried out in the Russian ISS utilization program, which consists of the Russian national program of fundamental and applied research in 11 research areas and international cooperative programs and contract activities. The US research program began with simple payloads in 2000 and was significantly expanded with the addition of the US Laboratory module Destiny in 2001, and its outfitting with seven research racks to date. The Canadian Space Agency (CSA), the European Space Agency (ESA) and the Japan Aerospace Exploration Agency (JAXA) have made use of international cooperative arrangements with both the US and Russia to implement a variety of investigations in diverse research areas, and in the case of ESA included the flights of crewmembers to ISS as part of Soyuz Science Missions. In the future, ESA and JAXA will add their own research modules, Columbus and Kibo, respectively, to expand research capabilities both inside and outside ISS. In the aftermath of the Columbia accident and the temporary grounding of the Space Shuttle fleet, all ISS logistics have relied on Russian Progress and Sopz vehicles. The Russian national program has continued as before the Shuttle accident, as have international cooperative programs and contract activities, both during long-duration expeditions and visiting taxi missions. In several instances, Russian international cooperative activities with JAXA and ESA have also involved the use of US facilities and crewmembers in successful truly multilateral efforts. The US research program was rapidly refocused after the Shuttle accident to rely on greatly reduced upmass, and for the first time in the ISS program, US research hardware was launched on Progress vehicles and returned with crews on Soyuz spacecraft. It is hoped that these small but significant steps in international cooperation will lead to even greater endeavors once the remaining research modules are added to ISS.

Laboratory directed research and development program, FY 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-02-01

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab) Laboratory Directed Research and Development Program FY 1996 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the projects supported and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The Berkeley Lab LDRD program is a critical tool for directing the Laboratory`s forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program provides themore » resources for Berkeley Lab scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also advances the Laboratory`s core competencies, foundations, and scientific capability, and permits exploration of exciting new opportunities. Areas eligible for support include: (1) Work in forefront areas of science and technology that enrich Laboratory research and development capability; (2) Advanced study of new hypotheses, new experiments, and innovative approaches to develop new concepts or knowledge; (3) Experiments directed toward proof of principle for initial hypothesis testing or verification; and (4) Conception and preliminary technical analysis to explore possible instrumentation, experimental facilities, or new devices.« less

A Program Like Any Other…Like None Other: Sustaining a Laboratory Science Technology Program for Deaf and Hard-of-Hearing Students

ERIC Educational Resources Information Center

Pagano, Todd; Ross, Annemarie D.; O'Neill, George J.

2012-01-01

A goal of the Laboratory Science Technology program at the National Technical Institute for the Deaf, a college of Rochester Institute of Technology, is to produce graduates with strong foundations in applied science, hands-on laboratory applications, and "soft skills" necessary for competitive employment as laboratory technicians.…

Evaluation of an external quality assessment program for HIV testing in Haiti, 2006-2011.

PubMed

Louis, Frantz Jean; Anselme, Renette; Ndongmo, Clement; Buteau, Josiane; Boncy, Jacques; Dahourou, Georges; Vertefeuille, John; Marston, Barbara; Balajee, S Arunmozhi

2013-12-01

To evaluate an external quality assessment (EQA) program for human immunodeficiency virus (HIV) rapid diagnostics testing by the Haitian National Public Health Laboratory (French acronym: LNSP). Acceptable performance was defined as any proficiency testing (PT) score more than 80%. The PT database was reviewed and analyzed to assess the testing performance of the participating laboratories and the impact of the program over time. A total of 242 laboratories participated in the EQA program from 2006 through 2011; participation increased from 70 laboratories in 2006 to 159 in 2011. In 2006, 49 (70%) laboratories had a PT score of 80% or above; by 2011, 145 (97.5%) laboratories were proficient (P < .05). The EQA program for HIV testing ensures quality of testing and allowed the LNSP to document improvements in the quality of HIV rapid testing over time.

Implementation of quality management systems and progress towards accreditation of National Tuberculosis Reference Laboratories in Africa

PubMed Central

de Dieu Iragena, Jean; Kao, Kekeletso; Erni, Donatelle; Mekonen, Teferi

2017-01-01

Background Laboratory services are essential at all stages of the tuberculosis care cascade, from diagnosis and drug resistance testing to monitoring response to treatment. Enabling access to quality services is a challenge in low-resource settings. Implementation of a strong quality management system (QMS) and laboratory accreditation are key to improving patient care. Objectives The study objective was to determine the status of QMS implementation and progress towards accreditation of National Tuberculosis Reference Laboratories (NTRLs) in the African Region. Method An online questionnaire was administered to NTRL managers in 47 World Health Organization Regional Office for Africa member states in the region, between February and April 2015, regarding the knowledge of QMS tools and progress toward implementation to inform strategies for tuberculosis diagnostic services strengthening in the region. Results A total of 21 laboratories (43.0%) had received SLMTA/TB-SLMTA training, of which 10 had also used the Global Laboratory Initiative accreditation tool. However, only 36.7% of NTRLs had received a laboratory audit, a first step in quality improvement. Most NTRLs participated in acid-fast bacilli microscopy external quality assurance (95.8%), although external quality assurance for other techniques was lower (60.4% for first-line drug susceptibility testing, 25.0% for second-line drug susceptibility testing, and 22.9% for molecular testing). Barriers to accreditation included lack of training and accreditation programmes. Only 28.6% of NTRLs had developed strategic plans and budgets which included accreditation. Conclusion Good foundations are in place on the continent from which to scale up accreditation efforts. Laboratory audits should be conducted as a first step in developing quality improvement action plans. Political commitment and strong leadership are needed to drive accreditation efforts; advocacy will require clear evidence of patient impact and cost-benefit. PMID:28879161

23. CONSTRUCTION PROGRESS VIEW LOOKING TOWARD EAST SHOWING CONCRETE BLOCK ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

23. CONSTRUCTION PROGRESS VIEW LOOKING TOWARD EAST SHOWING CONCRETE BLOCK CONSTRUCTION. INEEL PHOTO NUMBER NRTS-59-4305. - Idaho National Engineering Laboratory, Old Waste Calcining Facility, Scoville, Butte County, ID

19. CONSTRUCTION PROGRESS PHOTO SHOWING (TYPICALLY COMPLEX) WASTE HOLDING CELL ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

19. CONSTRUCTION PROGRESS PHOTO SHOWING (TYPICALLY COMPLEX) WASTE HOLDING CELL PIPING. INEEL PHOTO NUMBER NRTS-59-3212. - Idaho National Engineering Laboratory, Old Waste Calcining Facility, Scoville, Butte County, ID

15. CONSTRUCTION PROGRESS PHOTO SHOWING FORMS GOING UP ON ACCESS ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

15. CONSTRUCTION PROGRESS PHOTO SHOWING FORMS GOING UP ON ACCESS CORRIDOR. INEEL PHOTO NUMBER NRTS-59-336. - Idaho National Engineering Laboratory, Old Waste Calcining Facility, Scoville, Butte County, ID

7 CFR 90.3 - General.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) COMMODITY LABORATORY TESTING PROGRAMS... programs of laboratories certified and approved by the Science and Technology shall have good laboratory...

7 CFR 90.3 - [Reserved

Code of Federal Regulations, 2011 CFR

2011-01-01

..., Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) COMMODITY LABORATORY TESTING PROGRAMS... programs of laboratories certified and approved by the Science and Technology shall have good laboratory...

7 CFR 90.3 - General.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) COMMODITY LABORATORY TESTING PROGRAMS... programs of laboratories certified and approved by the Science and Technology shall have good laboratory...

7 CFR 90.3 - General.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) COMMODITY LABORATORY TESTING PROGRAMS... programs of laboratories certified and approved by the Science and Technology shall have good laboratory...

Guidelines for Biosafety Training Programs for Workers Assigned to BSL-3 Research Laboratories.

PubMed

Homer, Lesley C; Alderman, T Scott; Blair, Heather Ann; Brocard, Anne-Sophie; Broussard, Elaine E; Ellis, Robert P; Frerotte, Jay; Low, Eleanor W; McCarthy, Travis R; McCormick, Jessica M; Newton, JeT'Aime M; Rogers, Francine C; Schlimgen, Ryan; Stabenow, Jennifer M; Stedman, Diann; Warfield, Cheryl; Ntiforo, Corrie A; Whetstone, Carol T; Zimmerman, Domenica; Barkley, Emmett

2013-03-01

The Guidelines for Biosafety Training Programs for Workers Assigned to BSL-3 Research Laboratories were developed by biosafety professionals who oversee training programs for the 2 national biocontainment laboratories (NBLs) and the 13 regional biocontainment laboratories (RBLs) that participate in the National Institute of Allergy and Infectious Diseases (NIAID) NBL/RBL Network. These guidelines provide a general training framework for biosafety level 3 (BSL-3) high-containment laboratories, identify key training concepts, and outline training methodologies designed to standardize base knowledge, understanding, and technical competence of laboratory personnel working in high-containment laboratories. Emphasis is placed on building a culture of risk assessment-based safety through competency training designed to enhance understanding and recognition of potential biological hazards as well as methods for controlling these hazards. These guidelines may be of value to other institutions and academic research laboratories that are developing biosafety training programs for BSL-3 research.

Physiology undergraduate degree requirements in the U.S.

PubMed

VanRyn, Valerie S; Poteracki, James M; Wehrwein, Erica A

2017-12-01

Course-level learning objectives and core concepts for undergraduate physiology teaching exist. The next step is to consider how these resources fit into generalizable program-level guidelines for Bachelor of Science (BS) degrees in Physiology. In the absence of program-level guidelines for Physiology degree programs, we compiled a selective internal report to review degree requirements from 18 peer BS programs entitled "Physiology" in the United States (U.S.). There was a range of zero to three required semesters of math, physics, physics laboratory, general biology, biology laboratory, general chemistry, chemistry laboratory, organic chemistry, organic chemistry laboratory, biochemistry, biochemistry laboratory, anatomy, anatomy laboratory, core systems physiology, and physiology laboratory. Required upper division credits ranged from 11 to 31 and included system-specific, exercise and environmental, clinically relevant, pathology/disease-related, and basic science options. We hope that this information will be useful for all programs that consider themselves to be physiology, regardless of name. Reports such as this can serve as a starting point for collaboration among BS programs to improve physiology undergraduate education and best serve our students. Copyright © 2017 the American Physiological Society.

Safety in the Chemical Laboratory: Safety in the Chemistry Laboratories: A Specific Program.

ERIC Educational Resources Information Center

Corkern, Walter H.; Munchausen, Linda L.

1983-01-01

Describes a safety program adopted by Southeastern Louisiana University. Students are given detailed instructions on laboratory safety during the first laboratory period and a test which must be completely correct before they are allowed to return to the laboratory. Test questions, list of safety rules, and a laboratory accident report form are…

Mississippi Curriculum Framework for Medical Laboratory Technology Programs (CIP: 51.1004--Medical Laboratory Technology). Postsecondary Programs.

ERIC Educational Resources Information Center

Mississippi Research and Curriculum Unit for Vocational and Technical Education, State College.

This document, which is intended for use by community and junior colleges throughout Mississippi, contains curriculum frameworks for the course sequences in the medical laboratory technology program. Presented in the introductory section are a description of the program and suggested course sequence. Section I lists baseline competencies, and…

A Laboratory Safety Program at Delaware.

ERIC Educational Resources Information Center

Whitmyre, George; Sandler, Stanley I.

1986-01-01

Describes a laboratory safety program at the University of Delaware. Includes a history of the program's development, along with standard safety training and inspections now being implemented. Outlines a two-day laboratory safety course given to all graduate students and staff in chemical engineering. (TW)

USGS Laboratory Review Program Ensures Analytical Quality

USGS Publications Warehouse

Erdmann, David E.

1995-01-01

The USGS operates a review program for laboratories that analyze samples for USGS environmental investigations. This program has been effective in providing QA feedback to laboratories while ensuring that analytical data are consistent, of satisfactory quality, and meet the data objectives of the investigation.

ISO 15189 accreditation: Requirements for quality and competence of medical laboratories, experience of a laboratory I.

PubMed

Guzel, Omer; Guner, Ebru Ilhan

2009-03-01

Medical laboratories are the key partners in patient safety. Laboratory results influence 70% of medical diagnoses. Quality of laboratory service is the major factor which directly affects the quality of health care. The clinical laboratory as a whole has to provide the best patient care promoting excellence. International Standard ISO 15189, based upon ISO 17025 and ISO 9001 standards, provides requirements for competence and quality of medical laboratories. Accredited medical laboratories enhance credibility and competency of their testing services. Our group of laboratories, one of the leading institutions in the area, had previous experience with ISO 9001 and ISO 17025 Accreditation at non-medical sections. We started to prepared for ISO 15189 Accreditation at the beginning of 2006 and were certified in March, 2007. We spent more than a year to prepare for accreditation. Accreditation scopes of our laboratory were as follows: clinical chemistry, hematology, immunology, allergology, microbiology, parasitology, molecular biology of infection serology and transfusion medicine. The total number of accredited tests is 531. We participate in five different PT programs. Inter Laboratory Comparison (ILC) protocols are performed with reputable laboratories. 82 different PT Program modules, 277 cycles per year for 451 tests and 72 ILC program organizations for remaining tests have been performed. Our laboratory also organizes a PT program for flow cytometry. 22 laboratories participate in this program, 2 cycles per year. Our laboratory has had its own custom made WEB based LIS system since 2001. We serve more than 500 customers on a real time basis. Our quality management system is also documented and processed electronically, Document Management System (DMS), via our intranet. Preparatory phase for accreditation, data management, external quality control programs, personnel related issues before, during and after accreditation process are presented. Every laboratory has to concentrate on patient safety issues related to laboratory testing and should perform quality improvement projects.

Forming a Bose-Einstein Condensate

NASA Image and Video Library

2014-09-26

This sequence of false-color images shows the formation of a Bose-Einstein condensate in the Cold Atom Laboratory prototype at NASA Jet Propulsion Laboratory as the temperature gets progressively closer to absolute zero.

Customer Satisfaction Assessment at the Pacific Northwest National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderson, Dale N.; Sours, Mardell L.

2000-03-20

The Pacific Northwest National Laboratory (PNNL) is developing and implementing a customer satisfaction assessment program (CSAP) to assess the quality of research and development provided by the laboratory. We present the customer survey component of the PNNL CSAP. The customer survey questionnaire is composed of 2 major sections, Strategic Value and Project Performance. The Strategic Value section of the questionnaire consists of 5 questions that can be answered with a 5 point Likert scale response. These questions are designed to determine if a project is directly contributing to critical future national needs. The Project Performance section of the questionnaire consistsmore » of 9 questions that can be answered with a 5 point Likert scale response. These questions determine PNNL performance in meeting customer expectations. Many approaches could be used to analyze customer survey data. We present a statistical model that can accurately capture the random behavior of customer survey data. The properties of this statistical model can be used to establish a "gold standard'' or performance expectation for the laboratory, and then assess progress. The gold standard is defined from input from laboratory management --- answers to 4 simple questions, in terms of the information obtained from the CSAP customer survey, define the standard: *What should the average Strategic Value be for the laboratory project portfolio? *What Strategic Value interval should include most of the projects in the laboratory portfolio? *What should average Project Performance be for projects with a Strategic Value of about 2? *What should average Project Performance be for projects with a Strategic Value of about 4? We discuss how to analyze CSAP customer survey data with this model. Our discussion will include "lessons learned" and issues that can invalidate this type of assessment.« less

Lawrence Berkeley Laboratory Institutional Plan, FY 1993--1998

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-10-01

The FY 1993--1998 Institutional Plan provides an overview of the Lawrence Berkeley Laboratory mission, strategic plan, scientific initiatives, research programs, environment and safety program plans, educational and technology transfer efforts, human resources, and facilities needs. The Strategic Plan section identifies long-range conditions that can influence the Laboratory, potential research trends, and several management implications. The Initiatives section identifies potential new research programs that represent major long-term opportunities for the Laboratory and the resources required for their implementation. The Scientific and Technical Programs section summarizes current programs and potential changes in research program activity. The Environment, Safety, and Health section describesmore » the management systems and programs underway at the Laboratory to protect the environment, the public, and the employees. The Technology Transfer and Education programs section describes current and planned programs to enhance the nation's scientific literacy and human infrastructure and to improve economic competitiveness. The Human Resources section identifies LBL staff composition and development programs. The section on Site and Facilities discusses resources required to sustain and improve the physical plant and its equipment. The Resource Projections are estimates of required budgetary authority for the Laboratory's ongoing research programs. The plan is an institutional management report for integration with the Department of Energy's strategic planning activities that is developed through an annual planning process. The plan identifies technical and administrative directions in the context of the National Energy Strategy and the Department of Energy's program planning initiatives. Preparation of the plan is coordinated by the Office for Planning and Development from information contributed by the Laboratory's scientific and support divisions.« less

Human Genome Program Report. Part 1, Overview and Progress

DOE R&D Accomplishments Database

1997-11-01

This report contains Part 1 of a two-part report to reflect research and progress in the U.S. Department of Energy Human Genome Program from 1994 through 1996, with specified updates made just before publication. Part 1 consists of the program overview and report on progress.

Human genome program report. Part 1, overview and progress

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-11-01

This report contains Part 1 of a two-part report to reflect research and progress in the U.S. Department of Energy Human Genome Program from 1994 through 1996, with specified updates made just before publication. Part 1 consists of the program overview and report on progress.

20. CONSTRUCTION PROGRESS PHOTO OF INSTRUMENT PANEL IN PLACE IN ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

20. CONSTRUCTION PROGRESS PHOTO OF INSTRUMENT PANEL IN PLACE IN OPERATING CORRIDOR. INEEL PHOTO NUMBER NRTS-59-6091. - Idaho National Engineering Laboratory, Old Waste Calcining Facility, Scoville, Butte County, ID

Laboratory Directed Research and Development Program Assessment for FY 2016

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hatton, Diane; Flynn, Liz

2017-03-31

Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy in accordance with DOE Order 413.2C, and this report fulfills that requirement.

Laboratory Directed Research and Development Program Assessment for FY 2017

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderson, Jack; Flynn, Liz

Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy in accordance with DOE Order 413.2C. This report fulfills that requirement.

Management of Disused Radioactive Sealed Sources in Egypt - 13512

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mohamed, Y.T.; Hasan, M.A.; Lasheen, Y.F.

The future safe development of nuclear energy and progressive increasing use of sealed sources in medicine, research, industry and other fields in Egypt depends on the safe and secure management of disused radioactive sealed sources. In the past years have determined the necessity to formulate and apply the integrated management program for radioactive sealed sources to assure harmless and ecological rational management of disused sealed sources in Egypt. The waste management system in Egypt comprises operational and regulatory capabilities. Both of these activities are performed under legislations. The Hot Laboratories and Waste Management Center HLWMC, is considered as a centralizedmore » radioactive waste management facility in Egypt by law 7/2010. (authors)« less

GridAPPS-D Conceptual Design v1.0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Melton, Ronald B.; Schneider, Kevin P.; McDermott, Thomas E.

2017-05-31

The purpose of this document is to provide a conceptual design of the distribution system application development platform being developed for the U.S. Department of Energy’s Advanced Distribution Management System (ADMS) Program by the Grid Modernization Laboratory Consortium project GM0063. The platform will be referred to as GridAPPS-D. This document provides a high level, conceptual view of the platform and provides related background and contextual information. This document is intended to both educate readers about the technical work of the project and to serve as a point of reference for the project team. The document will be updated as themore » project progresses.« less

Laboratory kinetic studies of OH and CO2 relevant to upper atmospheric radiation balance

NASA Technical Reports Server (NTRS)

Nelson, David D.; Zahniser, Mark S.; Kolb, Charles E.

1994-01-01

During the first year of this program, we have made considerable progress toward the measurement of the dipole moments of vibrationally excited OH radicals. Our primary accomplishments have been 1) the modification of the original slit jet spectrometer for the study of radical species and 2) the observation of infrared chemiluminescence from the vibrationally excited OH radicals formed in the H + ozone reaction in the supersonic jet. We are optimistic that we will soon observe OH* laser induced fluorescence in the jet. Modulation of this fluorescence with microwave radiation in an applied electric field will be the final step required for the precise determination of the vibrational dependence of the OH dipole moment.

Science and Technology Review June 2005

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aufderheide, M

2005-05-03

This is the articles in this month's issue: (1) Close Collaborations Advance Progress in Genomic Research--Commentary by Elbert Branscomb; (2) Mining Genomes--Livermore computer programs help locate the stretches of DNA in gene deserts that regulate protein-making genes; (3) Shedding Light on Quantum Physics--Laboratory laser research builds from the foundation of Einstein's description of the quantization of light. (4) The Sharper Image for Surveillance--Speckle imaging-an image-processing technique used in astronomy is bringing long-distance surveillance into sharper focus. (5) Keeping Cool Close to the Sun--The specially coated gamma-ray spectrometer aboard the MESSENGER spacecraft will help scientists determine the abundance of elements inmore » Mercury's crust.« less

Proceedings of the 1988 International Meeting on Reduced Enrichment for Research and Test Reactors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-07-01

The international effort to develop and implement new research reactor fuels utilizing low-enriched uranium, instead of highly- enriched uranium, continues to make solid progress. This effort is the cornerstone of a widely shared policy aimed at reducing, and possibly eliminating, international traffic in highly-enriched uranium and the nuclear weapon proliferation concerns associated with this traffic. To foster direct communication and exchange of ideas among the specialists in this area, the Reduced Enrichment Research and Test Reactor (RERTR) Program, at Argonne National Laboratory, sponsored this meeting as the eleventh of a series which began 1978. Individual papers presented at the meetingmore » have been cataloged separately.« less

The Development of a Post-Baccalaureate Certificate Program in Molecular Diagnostics

PubMed Central

Williams, Gail S.; Brown, Judith D.; Keagle, Martha B.

2000-01-01

A post-baccalaureate certificate program in diagnostic molecular sciences was created in 1995 by the Diagnostic Genetic Sciences Program in the School of Allied Health at the University of Connecticut. The required on-campus lecture and laboratory courses include basic laboratory techniques, health care issues, cell biology, immunology, human genetics, research, management, and molecular diagnostic techniques and laboratory in molecular diagnostics. These courses precede a 6-month, full-time practicum at an affiliated full-service molecular laboratory. The practicum includes amplification and blotting methods, a research project, and a choice of specialized electives including DNA sequencing, mutagenesis, in situ hybridization methods, or molecular diagnostic applications in microbiology. Graduates of the program are immediately eligible to sit for the National Credentialing Agency examination in molecular biology to obtain the credential Clinical Laboratory Specialist in Molecular Biology (CLSp(MB). This description of the University of Connecticut program may assist other laboratory science programs in creating similar curricula. PMID:11232107

38 CFR 21.4277 - Discontinuance: unsatisfactory progress, conduct and attendance.

Code of Federal Regulations, 2010 CFR

2010-07-01

... progress, conduct and attendance. (a) Satisfactory pursuit of program. Entitlement to benefits for a... the pursuit of such program, continues to maintain satisfactory progress. If the veteran or eligible person does not maintain satisfactory progress, educational benefits will be discontinued by the...

[Role of the independent microbiology laboratory in supporting infection control programs in small to mid-sized hospitals].

PubMed

Yanagisawa, Hideji

2009-05-01

With the revision of the Medical Service Law in 2006 by the Japanese Ministry of Health, Labour and Welfare (MHLW), all healthcare institutions are now required to implement a healthcare risk management program including infection control program. At a national level, an infection control surveillance program (JANIS) was implemented in July 2007. Regular weekly, monthly, and yearly infection control surveillance reports from independent microbiology laboratories can make significant contributions to infection control programs in small to mid-sized hospitals; furthermore, such programs are consistent with the framework of the MHLW's objective of strengthening risk management in healthcare institutions. Against the backdrop of current efforts to improve risk management, independent laboratories can make a significant contribution. Independent laboratories must play a role beyond merely receiving and processing specimens for microbiological examination. In addition to generating results for patients, hospital epidemiological data that contribute to local infection control programs must be a value-added component of the service. A major obstacle for independent laboratories to make a significant contribution to risk management is the current reimbursement system, which makes it economically impossible for independent laboratories to support infection control programs in healthcare institutions.

Laboratory medicine education in Lithuania.

PubMed

Kucinskiene, Zita Ausrele; Bartlingas, Jonas

2011-01-01

In Lithuania there are two types of specialists working in medical laboratories and having a university degree: laboratory medicine physicians and medical biologists. Both types of specialists are officially being recognized and regulated by the Ministry of Health of Lithuania. Laboratory medicine physicians become specialists in laboratory medicine after an accredited 4-year multidisciplinary residency study program in Laboratory Medicine. The residency program curriculum for laboratory medicine physicians is presented. On December 9, 2009 the Equivalence of Standards for medical specialists was accepted and Lithuanian medical specialists in Clinical Chemistry and Laboratory Medicine can now apply for EC4 registration. Medical biologists become specialists in laboratory medicine after an accredited 2-year master degree multidisciplinary study program in Medical Biology, consisting of 80 credits. Various postgraduate advanced training courses for the continuous education of specialists in laboratory medicine were first introduced in 1966. Today it covers 1-2-week courses in different subspecialties of laboratory medicine. They are obligatory for laboratory medicine physicians for the renewal of their license. It is not compulsory for medical biologists to participate in these courses. The Centre of Laboratory Diagnostics represents a place for the synthesis and application of the basic sciences, the performance of research in various fields of laboratory medicine, as well as performance of thousands of procedures daily and provision of specific teaching programs.

7 CFR 94.5 - Charges for laboratory service.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) COMMODITY LABORATORY TESTING PROGRAMS... costs for analysis of mandatory egg product samples at Science and Technology Division laboratories... program. The costs for any other mandatory laboratory analyses and testing of an egg product's identity...

7 CFR 94.5 - Charges for laboratory service.

Code of Federal Regulations, 2011 CFR

2011-01-01

..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) COMMODITY LABORATORY TESTING PROGRAMS... costs for analysis of mandatory egg product samples at Science and Technology Division laboratories... program. The costs for any other mandatory laboratory analyses and testing of an egg product's identity...

7 CFR 94.5 - Charges for laboratory service.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) COMMODITY LABORATORY TESTING PROGRAMS... costs for analysis of mandatory egg product samples at Science and Technology Division laboratories... program. The costs for any other mandatory laboratory analyses and testing of an egg product's identity...

7 CFR 94.5 - Charges for laboratory service.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) COMMODITY LABORATORY TESTING PROGRAMS... costs for analysis of mandatory egg product samples at Science and Technology Division laboratories... program. The costs for any other mandatory laboratory analyses and testing of an egg product's identity...

38 CFR 21.7653 - Progress, conduct, and attendance.

Code of Federal Regulations, 2010 CFR

2010-07-01

... on which the school official who is responsible for determining whether a student is making progress...) Satisfactory pursuit of program. In order to receive educational assistance for pursuit of a program of education, a reservist must maintain satisfactory progress. Progress is unsatisfactory if the reservist does...

From the WPA to Workfare: It's Time for a Truly Progressive Government Work Program.

ERIC Educational Resources Information Center

Rose, Nancy E.

1990-01-01

Examines two government voluntary job creation programs: the Works Progress Administration in the 1930s and the Comprehensive Employment and Training Act in the 1970s, that have created conflicts with the logic of capitalist production for profit. Suggests principles and policies for a progressive government work program. (JOW)

Choosing the right laboratory: a review of clinical and forensic toxicology services for urine drug testing in pain management.

PubMed

Reisfield, Gary M; Goldberger, Bruce A; Bertholf, Roger L

2015-01-01

Urine drug testing (UDT) services are provided by a variety of clinical, forensic, and reference/specialty laboratories. These UDT services differ based on the principal activity of the laboratory. Clinical laboratories provide testing primarily focused on medical care (eg, emergency care, inpatients, and outpatient clinics), whereas forensic laboratories perform toxicology tests related to postmortem and criminal investigations, and drug-free workplace programs. Some laboratories now provide UDT specifically designed for monitoring patients on chronic opioid therapy. Accreditation programs for clinical laboratories have existed for nearly half a century, and a federal certification program for drug-testing laboratories was established in the 1980s. Standards of practice for forensic toxicology services other than workplace drug testing have been established in recent years. However, no accreditation program currently exists for UDT in pain management, and this review considers several aspects of laboratory accreditation and certification relevant to toxicology services, with the intention to provide guidance to clinicians in their selection of the appropriate laboratory for UDT surveillance of their patients on opioid therapy.

2nd Annual DOE-ERSP PI Meeting: Abstracts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hazen, Terry C.

2007-03-14

Welcome to the annual 2007 Environmental Remediation Sciences Program (ERSP) Principal Investigators (PIs) meeting. The purpose of this meeting is to bring together all of the lead PIs and key Co-PIs in the program to share and review the results of funded research from the past year. This meeting allows program managers from the Environmental Remediation Sciences Division (ERSD) within the Office of Biological and Environmental Research (OBER) to gauge the progress and significance of the funded research, and it is also an important venue to showcase ERSP research to interested parties within DOE and other invited federal agency representatives.more » Additionally, these meetings should serve as an opportunity for funded PIs to view their research in the context of the entire ERSP portfolio. Past ERSP meetings have been very important venues for detailed discussion of research results among PIs, development of new research ideas, fostering new collaborations and discussion with ERSD program managers on future research efforts and/or initiatives within the program. In short, these meetings are an important resource for both program managers and PIs. There will be only one ERSP PI meeting for 2007. In years past, ERSD has sponsored two PI meetings, one in the spring and a separate meeting in the fall that focused primarily on field research. However, this format tends to insulate laboratory-based research from the field research sponsored in the program and is incompatible with the ERSD view that laboratory-based research should progress towards understanding the relevant processes in natural environments at the field scale. Therefore the agenda for this year's PI meeting is well integrated with both lab-based and field-based projects, to allow for detailed discussion between PIs involved in each area. In the agenda, you will notice a more relaxed format than in years past. This year's meeting spans four days, but is less heavily regimented in terms of oral presentations and allows ample time for informal group discussions and poster presentations. The intent of this format is to foster informal discussion of research among PIs and ERSD program managers-discussion that is a hallmark of previous ERSD-sponsored meetings. Morning sessions will be dominated by oral presentations from PIs chosen by ERSD program managers to communicate key topics of research within the program. There is ample time during lunch and in the early afternoon for small group discussions/meetings prior to convening again in the later afternoon for oral presentations on field research conducted at the Integrated Field-Scale Subsurface Research Challenge sites (IFCs). Formal poster sessions begin after dinner. Abstracts for all poster presentations are listed within this meeting booklet. On behalf of the ERSD program managers and staff, we thank you for attending this year's PI meeting. We look forward to discussing the results of your research with you and your ideas for the future, and we hope that this meeting will continue as an important tradition for PIs in the program and serve as a valuable resource for your investigations.« less

A model to calculate the progression of the centre of pressure under the foot during gait analysis.

PubMed

Louey, Melissa Gar Yee; Mudge, Anita; Wojciechowski, Elizabeth; Sangeux, Morgan

2017-09-01

Pedobarography and the centre of pressure (COP) progression is useful to understand foot function. Pedobarography is often unavailable in gait laboratories or completed asynchronously to kinematic and kinetic data collection. This paper presents a model that allows calculation of COP progression synchronously using force plate data. The model is an adjunct to Plug-In-Gait and was applied to 49 typically developing children to create reference COP data. COP progressions were noted to spend 8% of stance behind the ankle joint centre, traverse lateral of the longitudinal axis of the foot through the midfoot for 76% of stance and finishing past the second metatarsal head on the medial side for 16% of stance. It is hoped the model will bridge the information gap for gait laboratories lacking pedobarography during foot assessments and will open up the possibility of retrospective research into COP progression based indices on kinematic data. Copyright © 2017 Elsevier B.V. All rights reserved.

21. CONSTRUCTION PROGRESS VIEW OF CALCINER VESSEL ON LOW BOY ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

21. CONSTRUCTION PROGRESS VIEW OF CALCINER VESSEL ON LOW BOY EN ROUTE TO FACILITY. INEEL PHOTO NUMBER NRTS-60-2487. - Idaho National Engineering Laboratory, Old Waste Calcining Facility, Scoville, Butte County, ID

22. CONSTRUCTION PROGRESS PHOTO SHOWING WORKERS LOWERING CALCINER VESSEL INTO ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

22. CONSTRUCTION PROGRESS PHOTO SHOWING WORKERS LOWERING CALCINER VESSEL INTO CELL THROUGH THE HATCH. INEEL PHOTO NUMBER NRTS-60-2485. - Idaho National Engineering Laboratory, Old Waste Calcining Facility, Scoville, Butte County, ID

Laboratory Directed Research and Development FY2001 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Al-Ayat, R

2002-06-20

Established by Congress in 1991, the Laboratory Directed Research and Development (LDRD) Program provides the Department of Energy (DOE)/National Nuclear Security Administration (NNSA) laboratories, like Lawrence Livermore National Laboratory (LLNL or the Laboratory), with the flexibility to invest up to 6% of their budget in long-term, high-risk, and potentially high payoff research and development (R&D) activities to support the DOE/NNSA's national security missions. By funding innovative R&D, the LDRD Program at LLNL develops and extends the Laboratory's intellectual foundations and maintains its vitality as a premier research institution. As proof of the Program's success, many of the research thrusts thatmore » started many years ago under LDRD sponsorship are at the core of today's programs. The LDRD Program, which serves as a proving ground for innovative ideas, is the Laboratory's most important single resource for fostering excellent science and technology for today's needs and tomorrow's challenges. Basic and applied research activities funded by LDRD enhance the Laboratory's core strengths, driving its technical vitality to create new capabilities that enable LLNL to meet DOE/NNSA's national security missions. The Program also plays a key role in building a world-class multidisciplinary workforce by engaging the Laboratory's best researchers, recruiting its future scientists and engineers, and promoting collaborations with all sectors of the larger scientific community.« less

An Alternative to the Physiological Psychology Laboratory: Identification of an Unknown Drug Through Behavioral Testing.

ERIC Educational Resources Information Center

Schumacher, Susan J.

1982-01-01

A laboratory project introduced physiological psychology students to research by requiring them to identify an unknown drug given to laboratory animals. Students read material about drugs and animal drug studies, designed behavioral tests, constructed the testing apparatus, conducted the tests, and wrote progress reports. (SR)

Research priorities on diarrhoeal diseases to support the Control of Diarrhoeal Diseases (CDD) programme in Indonesia.

PubMed

Sunoto

1986-01-01

A comprehensive program review of Indonesia's Control of Diarrheal Diseases (CDD) program conducted in 1983 indicated that considerable success has been achieved in this area. Oral rehydration solution (ORS) is widely available, there has been community involvement, a strong managerial structure has developed, baseline data on diarrhea morbidity and mortality are being collected, and staff have received adequate training. At the same time, there have been some problems: inadequate use of ORS, a lack of coordination among CDD programs, insufficient surveillance, budgetary problems, and a lack of laboratory support. During the last 10 years, diarrhea mortality in Indonesia has been reduced by 50-70%, to about 20,000 (20% of child mortality). The Government has established the goal of reducing mortality from diarrhea to less than 1% of child deaths by the year 2000. A major strategy for achieving this goal is integrating family planning, nutrition, maternal-child health, immunization, and CDD programs. Another strategy involves improving research in this area. Areas for further research include: epidemiologic studies, rehydration treatment, antidiarrheal agents, social aspects, immunity and vaccine development, and laboratory examination. The cause of diarrheal diseases is not only enteric infection, it is indirectly caused by acute respiratory infection, malnutrition, measles and other systemic infection as well as the health knowledge and education of the mother. Priority is to be given to 7 areas of research: 1) the use of home-prepared rehydration fluids, 2) feeding practices during acute diarrhea that can prevent chronic diarrhea and malnutrition, 3) the determinants of progression to chronic diarrhea, 4) the impact of simple health information on hygienic and feeding practices on mortality, 5) the potential of using traditional birth attendants in ORS campaigns, 6) traditional attitudes and practices, and 7) the effectiveness of traditional medicines in diarrhea treatment.

Evaluation of a Public-sector, Provider-initiated Cryptococcal Antigen Screening and Treatment Program, Western Cape, South Africa

PubMed Central

Smith, Mariette; Smith, Rachel; Osler, Meg; Kelly, Nicola; Cross, Anna; Boulle, Andrew; Meintjes, Graeme; Govender, Nelesh P.

2016-01-01

Background Screening for serum cryptococcal antigen (CrAg) may identify those at risk for disseminated cryptococcal disease (DCD), and pre-emptive fluconazole treatment may prevent progression to DCD. In August 2012, the Western Cape Province (WC), South Africa, adopted provider-initiated CrAg screening. We evaluated the implementation and effectiveness of this large-scale public-sector program during its first year, September 1, 2012—August 31, 2013. Methods We used data from the South African National Health Laboratory Service, WC provincial HIV program, and nationwide surveillance data for DCD. We assessed the proportion of eligible patients screened for CrAg (CrAg test done within 30 days of CD4 date) and the prevalence of CrAg positivity. Incidence of DCD among those screened was compared with those not screened. Results Of 4,395 eligible patients, 26.6% (n=1170) were screened. The proportion of patients screened increased from 15.9% in September 2012 to 36.6% in August 2013. The prevalence of positive serum CrAg was 2.1%. Treatment data were available for 13 of 24 CrAg-positive patients; nine of 13 were treated with fluconazole. Nine (0.8%) incident cases of DCD occurred among the 1170 patients who were screened for CrAg vs. 49 (1.5%) incident cases among the 3225 patients not screened (p=0.07). Conclusions Relatively few eligible patients were screened under the WC provider-initiated CrAg screening program. Unscreened patients were nearly twice as likely to develop DCD. CrAg screening can reduce the burden of DCD, but needs to be implemented well. To improve screening rates, countries should consider laboratory-based reflexive screening when possible. PMID:26926942

Safety approaches for high power modular laser operation

NASA Astrophysics Data System (ADS)

Handren, R. T.

1993-03-01

Approximately 20 years ago, a program was initiated at the Lawrence Livermore National Laboratory (LLNL) to study the feasibility of using lasers to separate isotopes of uranium and other materials. Of particular interest was the development of a uranium enrichment method for the production of commercial nuclear power reactor fuel to replace current more expensive methods. The Uranium Atomic Vapor Laser Isotope Separation (U-AVLIS) Program progressed to the point where a plant-scale facility to demonstrate commercial feasibility was built and is being tested. The U-AVLIS Program uses copper vapor lasers which pump frequency selective dye lasers to photoionize uranium vapor produced by an electron beam. The selectively ionized isotopes are electrostatically collected. The copper lasers are arranged in oscillator/amplifier chains. The current configuration consists of 12 chains, each with a nominal output of 800 W for a system output in excess of 9 kW. The system requirements are for continuous operation (24 h a day, 7 days a week) and high availability. To meet these requirements, the lasers are designed in a modular form allowing for rapid change-out of the lasers requiring maintenance. Since beginning operation in early 1985, the copper lasers have accumulated over 2 million unit hours at a greater than 90% availability. The dye laser system provides approximately 2.5 kW average power in the visible wavelength range. This large-scale laser system has many safety considerations, including high-power laser beams, high voltage, and large quantities (approximately 3000 gal) of ethanol dye solutions. The Laboratory's safety policy requires that safety controls be designed into any process, equipment, or apparatus in the form of engineering controls. Administrative controls further reduce the risk to an acceptable level. Selected examples of engineering and administrative controls currently being used in the U-AVLIS Program are described.

Risk prediction for chronic kidney disease progression using heterogeneous electronic health record data and time series analysis.

PubMed

Perotte, Adler; Ranganath, Rajesh; Hirsch, Jamie S; Blei, David; Elhadad, Noémie

2015-07-01

As adoption of electronic health records continues to increase, there is an opportunity to incorporate clinical documentation as well as laboratory values and demographics into risk prediction modeling. The authors develop a risk prediction model for chronic kidney disease (CKD) progression from stage III to stage IV that includes longitudinal data and features drawn from clinical documentation. The study cohort consisted of 2908 primary-care clinic patients who had at least three visits prior to January 1, 2013 and developed CKD stage III during their documented history. Development and validation cohorts were randomly selected from this cohort and the study datasets included longitudinal inpatient and outpatient data from these populations. Time series analysis (Kalman filter) and survival analysis (Cox proportional hazards) were combined to produce a range of risk models. These models were evaluated using concordance, a discriminatory statistic. A risk model incorporating longitudinal data on clinical documentation and laboratory test results (concordance 0.849) predicts progression from state III CKD to stage IV CKD more accurately when compared to a similar model without laboratory test results (concordance 0.733, P<.001), a model that only considers the most recent laboratory test results (concordance 0.819, P < .031) and a model based on estimated glomerular filtration rate (concordance 0.779, P < .001). A risk prediction model that takes longitudinal laboratory test results and clinical documentation into consideration can predict CKD progression from stage III to stage IV more accurately than three models that do not take all of these variables into consideration. © The Author 2015. Published by Oxford University Press on behalf of the American Medical Informatics Association.

Current progress on TPFI nulling architectures at Jet Propulsion Laboratory

NASA Technical Reports Server (NTRS)

Gappinger, Robert O.; Wallace, J. Kent; Bartos, Randall D.; Macdonald, Daniel R.; Brown, Kenneth A.

2005-01-01

Infrared interferometric nulling is a promising technology for exoplanet detection. Nulling research for the Terrestrial Planet Finder Interferometer has been exploring a variety of interferometer architectures at the Jet Propulsion Laboratory (JPL).

76 FR 15945 - National Voluntary Laboratory Accreditation Program (NVLAP) Workshop for Laboratories Interested...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-22

... Accreditation Program (NVLAP) is considering establishing an accreditation program for laboratories that test... the general accreditation criteria referenced in Sections 4 and 5 of the NIST handbook 150 to the test... accreditation, test and measurement equipment, personnel requirements, validation of test methods, and reporting...

NATIONAL LABORATORIES: Better Performance Reporting Could Aid Oversight of Laboratory-Directed R&D Program

DTIC Science & Technology

2001-09-01

Development ( LDRD ) program, which formalized a long-standing policy of allowing its multi-program national laboratories discretion to conduct self...initiated, independent research and development (R&D). DOE requires that LDRD work must focus on the advanced study of scientific or technical problems...

Evaluation of the Virtual Physiology of Exercise Laboratory Program

ERIC Educational Resources Information Center

Dobson, John L.

2009-01-01

The Virtual Physiology of Exercise Laboratory (VPEL) program was created to simulate the test design, data collection, and analysis phases of selected exercise physiology laboratories. The VPEL program consists of four modules: (1) cardiovascular, (2) maximal O[subscript 2] consumption [Vo[subscript 2max], (3) lactate and ventilatory thresholds,…

Final Progress Report for Collaborative Research: Aging of Black Carbon during Atmospheric Transport: Understanding Results from the DOE’s 2010 CARES and 2012 ClearfLo Campaigns

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mazzoleni, Claudio; Subramanian, R.

2016-08-31

Over the course of this project, we have analyzed data and samples from the Carbonaceous Aerosol and Radiative Effects Study (CARES) and the Clear air for London (ClearfLo) campaign, as well as conducted or participated in laboratory experiments designed to better understand black carbon mixing state and climate-relevant properties. The laboratory campaigns took place at the Pacific Northwest National Laboratory and Carnegie Mellon University to study various climate-relevant aerosol properties of different sources of soot mixing with secondary organic aerosol precursors. Results from some of these activities were summarized in the previous progress report. This final report presents the manuscriptsmore » that have been published (many in the period since the last progress report), lists presentations at different conferences based on grant-related activities, and presents some results that are likely to be submitted for publication in the near future.« less

NASA Multidisciplinary Design and Analysis Fellowship Program

NASA Technical Reports Server (NTRS)

1995-01-01

This report is a Year 1 interim report of the progress on the NASA multidisciplinary Design and Analysis Fellowship Program covering the period, January 1, 1995 through September 30, 1995. It summarizes progress in establishing the MDA Fellowship Program at Georgia Tech during the initial year. Progress in the advertisement of the program, recruiting results for the 1995-96 academic year, placement of the Fellows in industry during Summer 1995, program development at the M.S. and Ph.D. levels, and collaboration and dissemination of results are summarized in this report. Further details of the first year's progress will be included in the report from the Year 1 Workshop to be held at NASA Langley on December 7-8, 1995.

SSRL Emergency Response Shore Tool

NASA Technical Reports Server (NTRS)

Mah, Robert W.; Papasin, Richard; McIntosh, Dawn M.; Denham, Douglas; Jorgensen, Charles; Betts, Bradley J.; Del Mundo, Rommel

2006-01-01

The SSRL Emergency Response Shore Tool (wherein SSRL signifies Smart Systems Research Laboratory ) is a computer program within a system of communication and mobile-computing software and hardware being developed to increase the situational awareness of first responders at building collapses. This program is intended for use mainly in planning and constructing shores to stabilize partially collapsed structures. The program consists of client and server components, runs in the Windows operating system on commercial off-the-shelf portable computers, and can utilize such additional hardware as digital cameras and Global Positioning System devices. A first responder can enter directly, into a portable computer running this program, the dimensions of a required shore. The shore dimensions, plus an optional digital photograph of the shore site, can then be uploaded via a wireless network to a server. Once on the server, the shore report is time-stamped and made available on similarly equipped portable computers carried by other first responders, including shore wood cutters and an incident commander. The staff in a command center can use the shore reports and photographs to monitor progress and to consult with structural engineers to assess whether a building is in imminent danger of further collapse.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sjoreen, Terrence P

The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, 'Laboratory Directed Research and Development' (April 19, 2006), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries for all ORNL LDRD research activities supported during FY 2007. The associated FY 2007 ORNL LDRD Self-Assessment (ORNL/PPA-2008/2) provides financial data andmore » an internal evaluation of the program's management process. ORNL is a DOE multiprogram science, technology, and energy laboratory with distinctive capabilities in materials science and engineering, neutron science and technology, energy production and end-use technologies, biological and environmental science, and scientific computing. With these capabilities ORNL conducts basic and applied research and development (R&D) to support DOE's overarching mission to advance the national, economic, and energy security of the United States and promote scientific and technological innovation in support of that mission. As a national resource, the Laboratory also applies its capabilities and skills to specific needs of other federal agencies and customers through the DOE Work for Others (WFO) program. Information about the Laboratory and its programs is available on the Internet at http://www.ornl.gov/. LDRD is a relatively small but vital DOE program that allows ORNL, as well as other DOE laboratories, to select a limited number of R&D projects for the purpose of: (1) maintaining the scientific and technical vitality of the Laboratory; (2) enhancing the Laboratory's ability to address future DOE missions; (3) fostering creativity and stimulating exploration of forefront science and technology; (4) serving as a proving ground for new research; and (5) supporting high-risk, potentially high-value R&D. Through LDRD the Laboratory is able to improve its distinctive capabilities and enhance its ability to conduct cutting-edge R&D for its DOE and WFO sponsors. To meet the LDRD objectives and fulfill the particular needs of the Laboratory, ORNL has established a program with two components: the Director's R&D Fund and the Seed Money Fund. As outlined in Table 1, these two funds are complementary. The Director's R&D Fund develops new capabilities in support of the Laboratory initiatives, while the Seed Money Fund is open to all innovative ideas that have the potential for enhancing the Laboratory's core scientific and technical competencies. Provision for multiple routes of access to ORNL LDRD funds maximizes the likelihood that novel ideas with scientific and technological merit will be recognized and supported.« less

Decreasing the complications of renal osteodystrophy secondary to high phosphorus levels by using an innovative self-monitoring educational program.

PubMed

Zagaroli, A M; Zimmer, S M; Bowes, J M; Hartley, K S

1995-01-01

We wanted continuous ambulatory peritoneal dialysis (CAPD) and continuous cycling peritoneal dialysis (CCPD) patients to become more cognitive of the complications of high-serum phosphorus levels (> 6.0 mg/dL). The phosphorus self-monitoring program was designed to encourage patients to be more responsible for preventing the complications of renal osteodystrophy. Patients' phosphorus levels were graphed monthly on a poster in the exam room. Additional posters discussed their responsibilities to control phosphorus and the complications associated with hyperphosphatemia. All patients received an informative letter regarding the inception of the program in March 1994 and also were assured total anonymity of their laboratory results. At monthly clinic appointments, they received additional written information on phosphorus and discussed their phosphorus levels. Our teaching method proved effective in our CAPD/CCPD population. In March 1994, 31% of our patients had a phosphorus level greater than 6.0 mg/dL versus 10% in September 1994. The ability of patients to see their monthly progress and the comparison with other patients encouraged much interest and questions regarding phosphorus control.

Beryllium10: a free and simple tool for creating and managing group safety data sheets

PubMed Central

2014-01-01

Background Countless chemicals and mixtures are used in laboratories today, which all possess their own properties and dangers. Therefore, it is important to brief oneself about possible risks and hazards before doing any experiments. However, this task is laborious and time consuming. Summary Beryllium10 is a program, which supports users by carrying out a large part of the work such as collecting/importing data sets from different providers and compiling most of the information into a single group safety data sheet, which is suitable for having all necessary information at hand while an experiment is in progress. We present here the features of Beryllium10, their implementation, and their design and development criteria and ideas. Conclusion A program for creating and managing of group safety data sheets was developed and released as open source under GPL. The program provides a fast and clear user-interface, and well-conceived design for collecting and managing safety data. It is available for download from the web page http://beryllium.keksecks.de. PMID:24650446

The international fine aerosol networks

NASA Astrophysics Data System (ADS)

Cahill, Thomas A.

1993-04-01

The adoption by the United States of a PIXE-based protocol for its fine aerosol network, after open competitions involving numerous laboratories and methods, has encouraged cooperation with other countries possessing similar capabilities and similar needs. These informal cooperative programs, involving about a dozen countries at the end of 1991, almost all use PIXE as a major component of the analytical protocols. The University of California, Davis, Air Quality Group assisted such programs through indefinite loans of a quality assurance sampler, the IMPROVE Channel A, and analyses at no cost of a small fraction of the samples taken in a side-by-side configuration. In December 1991, the World Meteorological Organization chose a protocol essentially identical to IMPROVE for the Global Atmospheric Watch (GAW) network and began deploying units, the IMPROVE Channel A, to sites around the world. Preferred analyses include fine (less than about 2.5 μm) mass, ions by ion chromatography and elements by PIXE + PESA (or, lacking that, XRF). This paper will describe progress in both programs, giving examples of the utility of the data and projecting the future expansion of the network to about 20 GAW sites by 1994.

International Organization for Standardization (ISO) 15189.

PubMed

Schneider, Frank; Maurer, Caroline; Friedberg, Richard C

2017-09-01

The College of American Pathologists (CAP) offers a suite of laboratory accreditation programs, including one specific to accreditation to the international organization for standardization (ISO) 15189 standard for quality management specific to medical laboratories. CAP leaders offer an overview of ISO 15189 including its components, internal audits, occurrence management, document control, and risk management. The authors provide a comparison of its own ISO 15189 program, CAP 15189, to the CAP Laboratory Accreditation Program. The authors conclude with why laboratories should use ISO 15189. © The Korean Society for Laboratory Medicine.

Open-source LIMS in Vietnam: The path toward sustainability and host country ownership.

PubMed

Landgraf, Kenneth M; Kakkar, Reshma; Meigs, Michelle; Jankauskas, Paul T; Phan, Thi Thu Huong; Nguyen, Viet Nga; Nguyen, Duy Thai; Duong, Thanh Tung; Nguyen, Thi Hoa; Bond, Kyle B

2016-09-01

The objectives of this case report are as follows: to describe the process of establishing a national laboratory information management system (LIMS) program for clinical and public health laboratories in Vietnam; to evaluate the outcomes and lessons learned; and to present a model for sustainability based on the program outcomes that could be applied to diverse laboratory programs. This case report comprises a review of program documentation and records, including planning and budgetary records of the donor, monthly reports from the implementer, direct observation, and ad-hoc field reports from technical advisors and governmental agencies. Additional data on program efficacy and user acceptance were collected from routine monitoring of laboratory policies and operational practices. LIMS software was implemented at 38 hospital, public health and HIV testing laboratories in Vietnam. This LIMS was accepted by users and program managers as a useful tool to support laboratory processes. Implementation cost per laboratory and average duration of deployment decreased over time, and project stakeholders initiated transition of financing (from the donor to local institutions) and of system maintenance functions (from the implementer to governmental and site-level staff). Collaboration between the implementer in Vietnam and the global LIMS user community was strongly established, and knowledge was successfully transferred to staff within Vietnam. Implementing open-sourced LIMS with local development and support was a feasible approach towards establishing a sustainable laboratory informatics program that met the needs of health laboratories in Vietnam. Further effort to institutionalize IT support capacity within key government agencies is ongoing. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Towards a space-borne quantum gravity gradiometer: progress in laboratory demonstration

NASA Technical Reports Server (NTRS)

Yu, Nan; Kohel, James M.; Kellogg, James R.; Maleki, Lute

2005-01-01

This paper describes the working principles and technical benefits of atom-wave interferometer-based inertial sensors, and gives a progress report on the development of a quantum gravity gradiometer for space applications at JPL.

Progress In Electromagnetics Research Symposium (PIERS)

NASA Technical Reports Server (NTRS)

1993-01-01

The third Progress In Electromagnetics Research Symposium (PIERS) was held 12-16 Jul. 1993, at the Jet Propulsion Laboratory, California Institute of Technology, Pasadena, California. More than 800 presentations were made, and those abstracts are included in this publication.

16. CONSTRUCTION PROGRESS PHOTO SHOWING SURPLUS GUN BARREL BEING LOWERED ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

16. CONSTRUCTION PROGRESS PHOTO SHOWING SURPLUS GUN BARREL BEING LOWERED INTO PLACE FOR USE AS PIPE TUNNEL. INEEL PHOTO NUMBER NRTS-59-709. - Idaho National Engineering Laboratory, Old Waste Calcining Facility, Scoville, Butte County, ID

25. CONSTRUCTION PROGRESS AERIAL VIEW OF WASTE CALCINING FACILITY TAKEN ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

25. CONSTRUCTION PROGRESS AERIAL VIEW OF WASTE CALCINING FACILITY TAKEN WHEN STRUCTURE WAS 99 PERCENT COMPLETE. INEEL PHOTO NUMBER NRTS-60-5409. - Idaho National Engineering Laboratory, Old Waste Calcining Facility, Scoville, Butte County, ID

18. CONSTRUCTION PROGRESS PHOTO SHOWING SURPLUS GUN BARRELS IN PLACE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

18. CONSTRUCTION PROGRESS PHOTO SHOWING SURPLUS GUN BARRELS IN PLACE TO BE USED AS PIPE TUNNELS. INEEL PHOTO NUMBER NRTS-59-925. - Idaho National Engineering Laboratory, Old Waste Calcining Facility, Scoville, Butte County, ID

76 FR 24493 - Statement of Organization, Functions, and Delegations of Authority

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-02

... reorganization of the Laboratory Science, Policy, and Practice Program Office, Office of Surveillance... Laboratory Policy and Practice (CPGB), Laboratory Science, Policy, and Practice Program Office (CPG), and...

Laboratory challenges conducting international clinical research in resource-limited settings.

PubMed

Fitzgibbon, Joseph E; Wallis, Carole L

2014-01-01

There are many challenges to performing clinical research in resource-limited settings. Here, we discuss several of the most common laboratory issues that must be addressed. These include issues relating to organization and personnel, laboratory facilities and equipment, standard operating procedures, external quality assurance, shipping, laboratory capacity, and data management. Although much progress has been made, innovative ways of addressing some of these issues are still very much needed.

Laboratory automation in a functional programming language.

PubMed

Runciman, Colin; Clare, Amanda; Harkness, Rob

2014-12-01

After some years of use in academic and research settings, functional languages are starting to enter the mainstream as an alternative to more conventional programming languages. This article explores one way to use Haskell, a functional programming language, in the development of control programs for laboratory automation systems. We give code for an example system, discuss some programming concepts that we need for this example, and demonstrate how the use of functional programming allows us to express and verify properties of the resulting code. © 2014 Society for Laboratory Automation and Screening.

FY 1999 Annual Self-Evaluation Report of the Pacific Northwest National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Randy R. LaBarge

1999-11-05

This is a report of the Pacific Northwest National Laboratory's (Pacific Northwest's) FY1999 Annual Self-Evaluation Report. This report summarizes our progress toward accomplishment of the critical outcomes, objectives, and performance indicators as delineated in the FY1999 Performance Evaluation & Fee Agreement. It also summarizes our analysis of the results of Pacific Northwest's Division and Directorate annual self-assessments, and the implementation of our key operational improvement initiatives. Together, these provide an indication of how well we have used our Integrated Assessment processes to identify and plan improvements for FY2000. As you review the report you will find areas of significantly positivemore » progress; you will also note areas where I believe the Laboratory could make improvements. Overall, however, I believe you will be quite pleased to note that we have maintained, or exceeded, the high standards of performance we have set for the Laboratory.« less

Updated operational protocols for the U.S. Geological Survey Precipitation Chemistry Quality Assurance Project in support of the National Atmospheric Deposition Program

USGS Publications Warehouse

Wetherbee, Gregory A.; Martin, RoseAnn

2017-02-06

The U.S. Geological Survey Branch of Quality Systems operates the Precipitation Chemistry Quality Assurance Project (PCQA) for the National Atmospheric Deposition Program/National Trends Network (NADP/NTN) and National Atmospheric Deposition Program/Mercury Deposition Network (NADP/MDN). Since 1978, various programs have been implemented by the PCQA to estimate data variability and bias contributed by changing protocols, equipment, and sample submission schemes within NADP networks. These programs independently measure the field and laboratory components which contribute to the overall variability of NADP wet-deposition chemistry and precipitation depth measurements. The PCQA evaluates the quality of analyte-specific chemical analyses from the two, currently (2016) contracted NADP laboratories, Central Analytical Laboratory and Mercury Analytical Laboratory, by comparing laboratory performance among participating national and international laboratories. Sample contamination and stability are evaluated for NTN and MDN by using externally field-processed blank samples provided by the Branch of Quality Systems. A colocated sampler program evaluates the overall variability of NTN measurements and bias between dissimilar precipitation gages and sample collectors.This report documents historical PCQA operations and general procedures for each of the external quality-assurance programs from 2007 to 2016.

A Text-Computer Assisted Instruction Program as a Viable Alternative for Continuing Education in Laboratory Medicine.

ERIC Educational Resources Information Center

Bruce, A. Wayne

1986-01-01

Describes reasons for developing combined text and computer assisted instruction (CAI) teaching programs for delivery of continuing education to laboratory professionals, and mechanisms used for developing a CAI program on method evaluation in the clinical laboratory. Results of an evaluation of the software's cost effectiveness and instructional…

78 FR 59621 - Extension of the Current Fees for the Accredited Laboratory Program

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-27

... regulatory samples of raw or processed meat and poultry products, and through which a check sample program... Laboratory Program. Such accreditation allows laboratories to conduct analyses of official meat and poultry... employer. List of Subjects in 9 CFR Part 391 Fees and charges, Government employees, Meat inspection...

Annual progress report : for the period of January 2001 through December 2001 : Florida Transit Training Program (2001) : Florida Technical Assistance Program (2001)

DOT National Transportation Integrated Search

2001-01-01

The following progress report is intended to highlight the significant activities of the Florida Transit Training Program and Florida Technical Assistant Program for the 2001 year. Activities of the Florida Statewide Transit Training Program are pres...

Piezo-resistivity electric cone penetration technology investigation of the M-basin at the Savannah River Site, Aiken, South Carolina. Progress report, May 1, 1992--October 31, 1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bowers, B.; Rossabi, J.; Shinn, J.D. II

1997-05-01

This report documents the results of a combined field and laboratory investigation program to: (1) delineate the geologic layering and (2) determine the location of a dense non-aqueous liquid-phase (DNAPL) contaminated plume beneath the M Area Hazardous Waste Management Facility at the Savannah River Plant. During April of 1991, DNAPLs were detected in monitoring well (MSB-3D), located adjacent to the capped M-Area Settling Basin. Solvents in the well consisted mainly of tetrachloroethylene and trichloroethylene, which are also the main solvents found in groundwater in the M Area. In permeable soils, DNAPLs move downward rapidly due to their high density andmore » low viscosity as compared to water. Within the vadose zone, DNAPLs tend to be held by the less permeable clay and silts by capillary force. In the saturated zone, the downward movement is slowed by clays and silts and the DNAPL tends to pool on this layer, then spread laterally. The lateral movement continues until a permeable layer is encountered, which can be a sand lens, fracture or other high conductivity seam. The DNAPL then moves downward, until another low permeability layer is encountered. Applied Research Associates was contracted to conduct a program to: (1) field demonstrate the utility of Cone Penetration Technology to investigate DOE contaminant sites and, (2) conduct a laboratory and field program to evaluate the use of electric resistivity surveys to locate DNAPL contaminated soils. The field program was conducted in the M-Basin and laboratory tests were conducted on samples from the major stratigraphy units as identified in Eddy et. al. Cone Penetration Technology was selected to investigate the M-Basin as it: (1) is minimally invasive, (2) generates minimal waste, (3) is faster and less costly than drilling, (4) provides continuous, detailed in situ characterization data, (5) permits real-time data processing, and (6) can obtain soil, soil gas, and water samples without the need for a boring.« less

Analytical progresses of the International Olympic Committee and World Anti-Doping Agency Olympic laboratories.

PubMed

Georgakopoulos, Costas; Saugy, Martial; Giraud, Sylvain; Robinson, Neil; Alsayrafi, Mohammed

2012-07-01

The Summer Olympic Games constitute the biggest concentration of human sports and activities in a particular place and time since 776 BCE, when the written history of the Olympic Games in Olympia began. Summer and Winter Olympic anti-doping laboratories, accredited by the International Olympic Committee in the past and the World Anti-Doping Agency in the present times, acquire worldwide interest to apply all new analytical advancements in the fight against doping in sports, hoping that this major human event will not become dirty by association with this negative phenomenon. This article summarizes the new analytical progresses, technologies and knowledge used by the Olympic laboratories, which for the vast majority of them are, eventually, incorporated into routine anti-doping analysis.

Lack of grading agreement among international hemostasis external quality assessment programs

PubMed Central

Olson, John D.; Jennings, Ian; Meijer, Piet; Bon, Chantal; Bonar, Roslyn; Favaloro, Emmanuel J.; Higgins, Russell A.; Keeney, Michael; Mammen, Joy; Marlar, Richard A.; Meley, Roland; Nair, Sukesh C.; Nichols, William L.; Raby, Anne; Reverter, Joan C.; Srivastava, Alok; Walker, Isobel

2018-01-01

Laboratory quality programs rely on internal quality control and external quality assessment (EQA). EQA programs provide unknown specimens for the laboratory to test. The laboratory's result is compared with other (peer) laboratories performing the same test. EQA programs assign target values using a variety of methods statistical tools and performance assessment of ‘pass’ or ‘fail’ is made. EQA provider members of the international organization, external quality assurance in thrombosis and hemostasis, took part in a study to compare outcome of performance analysis using the same data set of laboratory results. Eleven EQA organizations using eight different analytical approaches participated. Data for a normal and prolonged activated partial thromboplastin time (aPTT) and a normal and reduced factor VIII (FVIII) from 218 laboratories were sent to the EQA providers who analyzed the data set using their method of evaluation for aPTT and FVIII, determining the performance for each laboratory record in the data set. Providers also summarized their statistical approach to assignment of target values and laboratory performance. Each laboratory record in the data set was graded pass/fail by all EQA providers for each of the four analytes. There was a lack of agreement of pass/fail grading among EQA programs. Discordance in the grading was 17.9 and 11% of normal and prolonged aPTT results, respectively, and 20.2 and 17.4% of normal and reduced FVIII results, respectively. All EQA programs in this study employed statistical methods compliant with the International Standardization Organization (ISO), ISO 13528, yet the evaluation of laboratory results for all four analytes showed remarkable grading discordance. PMID:29232255

Assessment of readiness for clinical decision support to aid laboratory monitoring of immunosuppressive care at U.S. liver transplant centers.

PubMed

Jacobs, J; Weir, C; Evans, R S; Staes, C

2014-01-01

Following liver transplantation, patients require lifelong immunosuppressive care and monitoring. Computerized clinical decision support (CDS) has been shown to improve post-transplant immunosuppressive care processes and outcomes. The readiness of transplant information systems to implement computerized CDS to support post-transplant care is unknown. a) Describe the current clinical information system functionality and manual and automated processes for laboratory monitoring of immunosuppressive care, b) describe the use of guidelines that may be used to produce computable logic and the use of computerized alerts to support guideline adherence, and c) explore barriers to implementation of CDS in U.S. liver transplant centers. We developed a web-based survey using cognitive interviewing techniques. We surveyed 119 U.S. transplant programs that performed at least five liver transplantations per year during 2010-2012. Responses were summarized using descriptive analyses; barriers were identified using qualitative methods. Respondents from 80 programs (67% response rate) completed the survey. While 98% of programs reported having an electronic health record (EHR), all programs used paper-based manual processes to receive or track immunosuppressive laboratory results. Most programs (85%) reported that 30% or more of their patients used external laboratories for routine testing. Few programs (19%) received most external laboratory results as discrete data via electronic interfaces while most (80%) manually entered laboratory results into the EHR; less than half (42%) could integrate internal and external laboratory results. Nearly all programs had guidelines regarding pre-specified target ranges (92%) or testing schedules (97%) for managing immunosuppressive care. Few programs used computerized alerting to notify transplant coordinators of out-of-range (27%) or overdue laboratory results (20%). Use of EHRs is common, yet all liver transplant programs were largely dependent on manual paper-based processes to monitor immunosuppression for post-liver transplant patients. Similar immunosuppression guidelines provide opportunities for sharing CDS once integrated laboratory data are available.

Los Alamos National Laboratory Prepares for Fire Season

ScienceCinema

L’Esperance, Manny

2018-01-16

Through the establishment of a Wildland Fire Program Office, and the Interagency Fire Base located on Laboratory property, Los Alamos National Laboratory is continuing and improving a program to prepare for wildland fire.

Los Alamos National Laboratory Prepares for Fire Season

DOE Office of Scientific and Technical Information (OSTI.GOV)

L’Esperance, Manny

Through the establishment of a Wildland Fire Program Office, and the Interagency Fire Base located on Laboratory property, Los Alamos National Laboratory is continuing and improving a program to prepare for wildland fire.

A laboratory medicine residency training program that includes clinical consultation and research.

PubMed

Spitzer, E D; Pierce, G F; McDonald, J M

1990-04-01

We describe a laboratory medicine residency training program that includes ongoing interaction with both clinical laboratories and clinical services as well as significant research experience. Laboratory medicine residents serve as on-call consultants in the interpretation of test results, design of testing strategies, and assurance of test quality. The consultative on-call beeper system was evaluated and is presented as an effective method of clinical pathology training that is well accepted by the clinical staff. The research component of the residency program is also described. Together, these components provide training in real-time clinical problem solving and prepare residents for the changing technological environment of the clinical laboratory. At the completion of the residency, the majority of the residents are qualified laboratory subspecialists and are also capable of running an independent research program.

Ernest Orlando Lawrence Berkeley National Laboratory institutional plan, FY 1996--2001

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-11-01

The FY 1996--2001 Institutional Plan provides an overview of the Ernest Orlando Lawrence Berkeley National Laboratory mission, strategic plan, core business areas, critical success factors, and the resource requirements to fulfill its mission in support of national needs in fundamental science and technology, energy resources, and environmental quality. The Laboratory Strategic Plan section identifies long-range conditions that will influence the Laboratory, as well as potential research trends and management implications. The Core Business Areas section identifies those initiatives that are potential new research programs representing major long-term opportunities for the Laboratory, and the resources required for their implementation. It alsomore » summarizes current programs and potential changes in research program activity, science and technology partnerships, and university and science education. The Critical Success Factors section reviews human resources; work force diversity; environment, safety, and health programs; management practices; site and facility needs; and communications and trust. The Resource Projections are estimates of required budgetary authority for the Laboratory`s ongoing research programs. The Institutional Plan is a management report for integration with the Department of Energy`s strategic planning activities, developed through an annual planning process. The plan identifies technical and administrative directions in the context of the national energy policy and research needs and the Department of Energy`s program planning initiatives. Preparation of the plan is coordinated by the Office of Planning and Communications from information contributed by the Laboratory`s scientific and support divisions.« less

Developing Technical Writing Skills in the Physical Chemistry Laboratory: A Progressive Approach Employing Peer Review

ERIC Educational Resources Information Center

Gragson, Derek E.; Hagen, John P.

2010-01-01

Writing formal "journal-style" lab reports is often one of the requirements chemistry and biochemistry students encounter in the physical chemistry laboratory. Helping students improve their technical writing skills is the primary reason this type of writing is a requirement in the physical chemistry laboratory. Developing these skills is an…

A Moveable Feast--A Progressive Approach to the Unit Operations Laboratory

ERIC Educational Resources Information Center

Conner, Wm. Curtis, Jr.; Hammond, Karl D.; Laurence, Robert L.

2011-01-01

The authors describe an alternative format for the senior laboratory in which students are allowed--indeed, expected--to communicate with previous groups and build on their results. The effect is a unit operations laboratory in which students are empowered to propose the experiments they wish to do and in which the cumulative experience of the…

76 FR 49491 - Medicare Program; Section 3113: The Treatment of Certain Complex Diagnostic Laboratory Tests...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-10

...] Medicare Program; Section 3113: The Treatment of Certain Complex Diagnostic Laboratory Tests Demonstration... code under the Treatment of Certain Complex Diagnostic Laboratory Tests Demonstration. The deadline for... interested parties of an opportunity to participate in the Treatment of Certain Complex Diagnostic Laboratory...

Creating a sustainable culture of quality through the SLMTA programme in a district hospital laboratory in Kenya.

PubMed

Maruti, Phidelis M; Mulianga, Ekesa A; Wambani, Lorna N; Wafula, Melda N; Mambo, Fidelis A; Mutisya, Shadrack M; Wakaria, Eric N; Mbati, Erick M; Amayo, Angela A; Majani, Jonathan M; Nyary, Bryan; Songwe, Kilian A

2014-01-01

Bungoma District Hospital Laboratory (BDHL), which supports a 200-bed referral facility, began its Strengthening Laboratory Management Toward Accreditation (SLMTA) journey in 2011 together with eight other laboratories in the second round of SLMTA rollout in Kenya. To describe how the SLMTA programme and enhanced quality interventions changed the culture and management style at BDHL and instilled a quality system designed to sustain progress for years to come. SLMTA implementation followed the standard three-workshop series, mentorship site visits and audits. In order to build sustainability of progress, BDHL integrated quality improvement processes into its daily operations. The lab undertook a process of changing its internal culture to align all hospital stakeholders - including upper management, clinicians, laboratory staff and maintenance staff - to the mission of sustainable quality practices at BDHL. After 16 months in the SLMTA programme, BDHL improved from zero stars (38%) to four stars (89%). Over a period of two to three years, external quality assessment results improved from 47% to 87%; staff punctuality increased from 49% to 82%; clinician complaints decreased from 83% to 16; rejection rates decreased from 12% to 3%; and annual equipment repairs decreased from 40 to 15. Twelve months later the laboratory scored three stars (81%) in an external surveillance audit conducted by Kenya Accreditation Service (KENAS). Management buy-in, staff participation, use of progress-monitoring tools and feedback systems, as well as incorporation of improvement processes into routine daily activities, were vital in developing and sustaining a culture of quality improvement.

CONSTRUCTION PROGRESS PHOTO OF REMOTE ANALYTICAL FACILITY (CPP627). INL PHOTO ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

CONSTRUCTION PROGRESS PHOTO OF REMOTE ANALYTICAL FACILITY (CPP-627). INL PHOTO NUMBER NRTS-54-12124. Unknown Photographer, 9/21/1954 - Idaho National Engineering Laboratory, Idaho Chemical Processing Plant, Fuel Reprocessing Complex, Scoville, Butte County, ID

CONSTRUCTION PROGRESS PHOTO SHOWING WEST STORAGE BASIN AT FUEL STORAGE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

CONSTRUCTION PROGRESS PHOTO SHOWING WEST STORAGE BASIN AT FUEL STORAGE BUILDING (CPP-603). INL PHOTO NUMBER NRTS-51-689. Unknown Photographer, 1950 - Idaho National Engineering Laboratory, Idaho Chemical Processing Plant, Fuel Reprocessing Complex, Scoville, Butte County, ID

78 FR 65705 - Request for Comments on the Annual Progress Report on the Outer Continental Shelf (OCS) Oil and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-01

... (Five Year Program). The Annual Progress Report is available for review at: www.boem.gov/Five-Year-Program-Annual-Progress-Report/ . Information on the Five Year Program is available online at http://www... final on August 27, 2012, after the required 60-day congressional review period. Section 18(e) of the...

Harmonization of good laboratory practice requirements and laboratory accreditation programs.

PubMed

Royal, P D

1994-09-01

Efforts to harmonize Good Laboratory Practice (GLP) requirements have been underway through the Organization for Economic Cooperation and Development (OECD) since 1981. In 1985, a GLP panel was established to facilitate the practical implementation of the OECD/GLP program. Through the OECD/GLP program, Memoranda of Understanding (MOU) agreements which foster requirements for reciprocal data and study acceptance and unified GLP standards have been developed among member countries. Three OECD Consensus Workshops and three inspectors training workshops have been held. In concert with these efforts, several OECD countries have developed GLP accreditation programs, managed by local health and environmental ministries. In addition, Canada and the United States are investigating Laboratory Accreditation programs for environmental monitoring assessment and GLP-regulated studies. In the European Community (EC), the need for quality standards specifying requirements for production and international trade has promoted International Standards Organization (ISO) certification for certain products. ISO-9000 standards identify requirements for certification of quality systems. These certification programs may affect the trade and market of laboratories conducting GLP studies. Two goals identified by these efforts are common to both programs: first, harmonization and recognition of requirements, and second, confidence in the rigor of program components used to assess the integrity of data produced and study activities. This confidence can be promoted, in part, through laboratory inspection and screening processes. However, the question remains, will data produced by sanctioned laboratories be mutually accepted on an international basis?(ABSTRACT TRUNCATED AT 250 WORDS)

Interstellar PAH Analogs in the Laboratory: Comparison with Astronomical Data

NASA Technical Reports Server (NTRS)

Salama, Farid

2005-01-01

Polycyclic Aromatic Hydrocarbons (PAHs) are an important and ubiquitous component of carbon-bearing materials in space. PAHs are the best-known candidates to account for the IR emission bands (UIR bands) and PAH spectral features are now being used as new probes of the ISM. PAHs are also thought to be among the carriers of the diffuse interstellar absorption bands (DIBs). In the model dealing with the interstellar spectral features, PAHs are present as a mixture of radicals, ions and neutral species. PAH ionization states reflect the ionization balance of the medium while PAH size, composition, and structure reflect the energetic and chemical history of the medium. A major challenge for laboratory astrophysics is to reproduce (in a realistic way) the physical conditions that exist in the emission and/or absorption interstellar zones. An extensive laboratory program has been developed at NASA Ames to assess the physical and chemical properties of PAHs in such environments and to describe how they influence the radiation and energy balance in space and the interstellar chemistry. In particular, laboratory experiments provide measurements of the spectral characteristics of interstellar PAH analogs from the ultraviolet and visible range to the infrared range for comparison with astronomical data. This paper will focus on the recent progress made in the laboratory to measure the direct absorption spectra of neutral and ionized PAHs in the near-UV and visible range. Intrinsic band profiles and band positions of cold gas-phase PAHs can now be measured with high-sensitivity spectroscopy and directly compared to the astronomical data. Preliminary conclusions from the comparison of the laboratory data with astronomical observations will also be presented.