The Naval Health Research Center Respiratory Disease Laboratory.

PubMed

Ryan, M; Gray, G; Hawksworth, A; Malasig, M; Hudspeth, M; Poddar, S

2000-07-01

Concern about emerging and reemerging respiratory pathogens prompted the development of a respiratory disease reference laboratory at the Naval Health Research Center. Professionals working in this laboratory have instituted population-based surveillance for pathogens that affect military trainees and responded to threats of increased respiratory disease among high-risk military groups. Capabilities of this laboratory that are unique within the Department of Defense include adenovirus testing by viral shell culture and microneutralization serotyping, influenza culture and hemagglutination inhibition serotyping, and other special testing for Streptococcus pneumoniae, Streptococcus pyogenes, Mycoplasma pneumonia, and Chlamydia pneumoniae. Projected capabilities of this laboratory include more advanced testing for these pathogens and testing for other emerging pathogens, including Bordetella pertussis, Legionella pneumoniae, and Haemophilus influenzae type B. Such capabilities make the laboratory a valuable resource for military public health.

Bringing the excitement and motivation of research to students; Using inquiry and research-based learning in a year-long biochemistry laboratory : Part II-research-based laboratory-a semester-long research approach using malate dehydrogenase as a research model.

PubMed

Knutson, Kristopher; Smith, Jennifer; Nichols, Paul; Wallert, Mark A; Provost, Joseph J

2010-09-01

Research-based learning in a teaching environment is an effective way to help bring the excitement and experience of independent bench research to a large number of students. The program described here is the second of a two-semester biochemistry laboratory series. Here, students are empowered to design, execute and analyze their own experiments for the entire semester. This style of laboratory replaces a variety of shorter labs in favor of an in depth research-based learning experience. The concept is to allow students to function in independent research groups. The research projects are focused on a series of wild-type and mutant clones of malate dehydrogenase. A common research theme for the laboratory helps instructors administer the course and is key to delivering a research opportunity to a large number of students. The outcome of this research-based learning laboratory results in students who are much more confident and skilled in critical areas in biochemistry and molecular biology. Students with research experience have significantly higher confidence and motivation than those students without a previous research experience. We have also found that all students performed better in advanced courses and in the workplace. Copyright © 2010 International Union of Biochemistry and Molecular Biology, Inc.

An Overview of the Computational Physics and Methods Group at Los Alamos National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baker, Randal Scott

CCS Division was formed to strengthen the visibility and impact of computer science and computational physics research on strategic directions for the Laboratory. Both computer science and computational science are now central to scientific discovery and innovation. They have become indispensable tools for all other scientific missions at the Laboratory. CCS Division forms a bridge between external partners and Laboratory programs, bringing new ideas and technologies to bear on today’s important problems and attracting high-quality technical staff members to the Laboratory. The Computational Physics and Methods Group CCS-2 conducts methods research and develops scientific software aimed at the latest andmore » emerging HPC systems.« less

Virtual Laboratory Enabling Collaborative Research in Applied Vehicle Technologies

NASA Technical Reports Server (NTRS)

Lamar, John E.; Cronin, Catherine K.; Scott, Laura E.

2005-01-01

The virtual laboratory is a new technology, based on the internet, that has had wide usage in a variety of technical fields because of its inherent ability to allow many users to participate simultaneously in instruction (education) or in the collaborative study of a common problem (real-world application). The leadership in the Applied Vehicle Technology panel has encouraged the utilization of this technology in its task groups for some time and its parent organization, the Research and Technology Agency, has done the same for its own administrative use. This paper outlines the application of the virtual laboratory to those fields important to applied vehicle technologies, gives the status of the effort, and identifies the benefit it can have on collaborative research. The latter is done, in part, through a specific example, i.e. the experience of one task group.

National Exposure Research Laboratory

EPA Pesticide Factsheets

The Ecosystems Research Division of EPA’s National Exposure Research Laboratory, conducts research on organic and inorganic chemicals, greenhouse gas biogeochemical cycles, and land use perturbations that create stressor exposures and potentia risk

Radar research at The Pennsylvania State University Radar and Communications Laboratory

NASA Astrophysics Data System (ADS)

Narayanan, Ram M.

2017-05-01

The Radar and Communications Laboratory (RCL) at The Pennsylvania State University is at the forefront of radar technology and is engaged in cutting edge research in all aspects of radar, including modeling and simulation studies of novel radar paradigms, design and development of new types of radar architectures, and extensive field measurements in realistic scenarios. This paper summarizes the research at The Pennsylvania State University's Radar and Communications Laboratory and relevant collaborative research with several groups over the past 15 years in the field of radar and related technologies, including communications, radio frequency identification (RFID), and spectrum sensing.

Experiences of mentors training underrepresented undergraduates in the research laboratory.

PubMed

Prunuske, Amy J; Wilson, Janelle; Walls, Melissa; Clarke, Benjamin

2013-01-01

Successfully recruiting students from underrepresented groups to pursue biomedical science research careers continues to be a challenge. Early exposure to scientific research is often cited as a powerful means to attract research scholars with the research mentor being critical in facilitating the development of an individual's science identity and career; however, most mentors in the biological sciences have had little formal training in working with research mentees. To better understand mentors' experiences working with undergraduates in the laboratory, we conducted semistructured interviews with 15 research mentors at a public university in the Midwest. The interviewed mentors were part of a program designed to increase the number of American Indians pursuing biomedical/biobehavioral research careers and represented a broad array of perspectives, including equal representation of male and female mentors, mentors from underrepresented groups, mentors at different levels of their careers, and mentors from undergraduate and professional school departments. The mentors identified benefits and challenges in being an effective mentor. We also explored what the term underrepresented means to the mentors and discovered that most of the mentors had an incomplete understanding about how differences in culture could contribute to underrepresented students' experience in the laboratory. Our interviews identify issues relevant to designing programs and courses focused on undergraduate student research.

Experiences of Mentors Training Underrepresented Undergraduates in the Research Laboratory

PubMed Central

Prunuske, Amy J.; Wilson, Janelle; Walls, Melissa; Clarke, Benjamin

2013-01-01

Successfully recruiting students from underrepresented groups to pursue biomedical science research careers continues to be a challenge. Early exposure to scientific research is often cited as a powerful means to attract research scholars with the research mentor being critical in facilitating the development of an individual's science identity and career; however, most mentors in the biological sciences have had little formal training in working with research mentees. To better understand mentors’ experiences working with undergraduates in the laboratory, we conducted semistructured interviews with 15 research mentors at a public university in the Midwest. The interviewed mentors were part of a program designed to increase the number of American Indians pursuing biomedical/biobehavioral research careers and represented a broad array of perspectives, including equal representation of male and female mentors, mentors from underrepresented groups, mentors at different levels of their careers, and mentors from undergraduate and professional school departments. The mentors identified benefits and challenges in being an effective mentor. We also explored what the term underrepresented means to the mentors and discovered that most of the mentors had an incomplete understanding about how differences in culture could contribute to underrepresented students’ experience in the laboratory. Our interviews identify issues relevant to designing programs and courses focused on undergraduate student research. PMID:24006389

Occupational health hazards in the interventional laboratory: progress report of the Multispecialty Occupational Health Group.

PubMed

Miller, Donald L; Klein, Lloyd W; Balter, Stephen; Norbash, Alexander; Haines, David; Fairobent, Lynne; Goldstein, James A

2010-09-01

The Multispecialty Occupational Health Group (MSOHG), formed in 2005, is an informal coalition of societies representing professionals who work in, or are concerned with, interventional fluoroscopy. The group's long-term goals are to improve occupational health and operator and staff safety in the interventional laboratory while maintaining quality patient care and optimal use of the laboratory. MSOHG has conducted a dialogue with equipment manufacturers and has developed a list of specific objectives for research and development. The group has also represented the member societies in educating regulators, in educating interventionalists, and in fostering and collaborating on research into occupational health issues affecting interventionalists. Not least of the group's accomplishments, as a result of their collaboration in MSOHG, the group's members have developed a mutual respect that can serve as a basis for joint efforts in the future among interventionalists of different medical specialties. Copyright 2010 SIR. Published by Elsevier Inc. All rights reserved.

Entrance to the NACA's Flight Propulsion Research Laboratory

NASA Image and Video Library

1948-08-21

The sign near the entrance of the National Advisory Committee for Aeronautics (NACA) Flight Propulsion Research Laboratory. The name was changed several weeks later to the Lewis Flight Propulsion Laboratory in honor of the NACA’s former Director of Aeronautical Research, George W. Lewis. The research laboratory has had five different names since its inception in 1941. The Cleveland laboratory was originally known as the NACA Aircraft Engine Research Laboratory. In 1947 it was renamed the NACA Flight Propulsion Research Laboratory to reflect the expansion of the research activities beyond just engines. Following the death of George Lewis, the name was changed to the NACA Lewis Flight Propulsion Laboratory in September 1948. On October 1, 1958, the lab was incorporated into the new NASA space agency, and it was renamed the NASA Lewis Research Center. Following John Glenn’s flight on the space shuttle, the name was changed again to the NASA Glenn Research Center on March 1, 1999. From his office in Washington DC, George Lewis managed the aeronautical research conducted at the NACA for over 20 years. His most important accomplishment, however, may have been an investigative tour of German research facilities in the fall of 1936. The visit resulted in the broadening of the scope of the NACA’s research and the physical expansion that included the new engine laboratory in Cleveland.

Air Force Research Laboratory Preparation for Year 2000.

DTIC Science & Technology

1998-10-05

Air Force Research Laboratory , Phillips Research Site , Kirkland Air Force Base, New...Pentagon, Washington, D.C. 20301-1900. The identity of each writer and caller is fully protected. Acronym AFRL Air Force Research Laboratory INSPECTOR...completion of the implementation phase was May 31, 1999. Air Force Research Laboratory . The Air Force Research

Helical Explosive Flux Compression Generator Research at the Air Force Research Laboratory

DTIC Science & Technology

1999-06-01

Air Force Research Laboratory Kirtland AFB...ORGANIZATION NAME(S) AND ADDRESS(ES) Directed Energy Directorate, Air Force Research Laboratory Kirtland AFB, NM 8. PERFORMING ORGANIZATION REPORT...in support of the Air Force Research Laboratory ( AFRL ) explosive pulsed power program. These include circuit codes such as Microcap and

Network Science Research Laboratory (NSRL) Discrete Event Toolkit

DTIC Science & Technology

2016-01-01

ARL-TR-7579 ● JAN 2016 US Army Research Laboratory Network Science Research Laboratory (NSRL) Discrete Event Toolkit by...Laboratory (NSRL) Discrete Event Toolkit by Theron Trout and Andrew J Toth Computational and Information Sciences Directorate, ARL...Research Laboratory (NSRL) Discrete Event Toolkit 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Theron Trout

Infusing Bioinformatics and Research-Like Experience into a Molecular Biology Laboratory Course

ERIC Educational Resources Information Center

Nogaj, Luiza A.

2014-01-01

A nine-week laboratory project designed for a sophomore level molecular biology course is described. Small groups of students (3-4 per group) choose a tumor suppressor gene (TSG) or an oncogene for this project. Each group researches the role of their TSG/oncogene from primary literature articles and uses bioinformatics engines to find the gene…

Human Laboratory Paradigms in Alcohol Research

PubMed Central

Plebani, Jennifer G.; Ray, Lara A.; Morean, Meghan E.; Corbin, William R.; Mackillop, James; Amlung, Michael; King, Andrea C.

2014-01-01

Human laboratory studies have a long and rich history in the field of alcoholism. Human laboratory studies have allowed for advances in alcohol research in a variety of ways, including elucidating of the neurobehavioral mechanisms of risk, identifying phenotypically distinct sub-types of alcohol users, investigating of candidate genes underlying experimental phenotypes for alcoholism, and testing mechanisms of action of alcoholism pharmacotherapies on clinically-relevant translational phenotypes, such as persons exhibiting positive-like alcohol effects or alcohol craving. Importantly, the field of human laboratory studies in addiction has progressed rapidly over the past decade and has built upon earlier findings of alcohol's neuropharmacological effects to advancing translational research on alcoholism etiology and treatment. To that end, the new generation of human laboratory studies has focused on applying new methodologies, further refining alcoholism phenotypes, and translating these findings to studies of alcoholism genetics, medication development, and pharmacogenetics. The combination of experimental laboratory approaches with recent developments in neuroscience and pharmacology has been particularly fruitful in furthering our understanding of the impact of individual differences in alcoholism risk and in treatment response. This review of the literature focuses on human laboratory studies of subjective intoxication, alcohol craving, anxiety, and behavioral economics. Each section discusses opportunities for phenotype refinement under laboratory conditions, as well as its application to translational science of alcoholism. A summary and recommendations for future research are also provided. PMID:22309888

Battelle's Marine Research Laboratory, Sequim

DOE Office of Scientific and Technical Information (OSTI.GOV)

Becker, C.D.; Strand, J.A.

Scientists at Battelle's Marine Research Laboratory (MRL) in Sequim, Washington study the effect of human activities on marine ecosystems, with emphasis on near shore and estuarine environments. The laboratory provides research and development assistance to industry and government agencies engaged in management of marine technologies, operation of coastal power utilities, protection of the marine environment, and related areas. This paper outlines and discusses the functions of Battelle's MRL, it's history, it's unique features, it's areas of expertise, it's current programs, and it's cooperating agencies.

LDRD 2013 Annual Report: Laboratory Directed Research and Development Program Activities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bookless, W.

This LDRD project establishes a research program led by Jingguang Chen, who has started a new position as a Joint Appointee between BNL and Columbia University as of FY2013. Under this project, Dr. Chen will establish a new program in catalysis science at BNL and Columbia University. The LDRD program will provide initial research funding to start research at both BNL and Columbia. At BNL, Dr. Chen will initiate laboratory research, including hiring research staff, and will collaborate with the existing BNL catalysis and electrocatalysis research groups. At Columbia, a subcontract to Dr. Chen will provide startup funding for hismore » laboratory research, including initial graduate student costs. The research efforts will be linked under a common Catalysis Program in Sustainable Fuels. The overall impact of this project will be to strengthen the BNL catalysis science program through new linked research thrusts and the addition of an internationally distinguished catalysis scientist.« less

41 CFR 101-25.109 - Laboratory and research equipment.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Laboratory and research...-General Policies § 101-25.109 Laboratory and research equipment. (a) This section prescribes controls for use by Federal agencies in managing laboratory and research equipment in Federal laboratories...

41 CFR 101-25.109 - Laboratory and research equipment.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 41 Public Contracts and Property Management 2 2014-07-01 2012-07-01 true Laboratory and research...-General Policies § 101-25.109 Laboratory and research equipment. (a) This section prescribes controls for use by Federal agencies in managing laboratory and research equipment in Federal laboratories...

41 CFR 101-25.109 - Laboratory and research equipment.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 41 Public Contracts and Property Management 2 2012-07-01 2012-07-01 false Laboratory and research...-General Policies § 101-25.109 Laboratory and research equipment. (a) This section prescribes controls for use by Federal agencies in managing laboratory and research equipment in Federal laboratories...

Fuels and Lubrication Researcher at the Aircraft Engine Research Laboratory

NASA Image and Video Library

1943-08-21

A researcher at the National Advisory Committee for Aeronautics (NACA) Aircraft Engine Research Laboratory studies the fuel ignition process. Improved fuels and lubrication was an area of particular emphasis at the laboratory during World War II. The military sought to use existing types of piston engines in order to get large numbers of aircraft into the air as quickly as possible. To accomplish its goals, however, the military needed to increase the performance of these engines without having to wait for new models or extensive redesigns. The Aircraft Engine Research Laboratory was called on to lead this effort. The use of superchargers successfully enhanced engine performance, but the resulting heat increased engine knock [fuel detonation] and structural wear. These effects could be offset with improved cooling, lubrication, and fuel mixtures. The NACA researchers in the Fuels and Lubrication Division concentrated on new synthetic fuels, higher octane fuels, and fuel-injection systems. The laboratory studied 16 different types of fuel blends during the war, including extensive investigations of triptane and xylidine.

2nd Annual Postdoc Research Day: US Army Research Laboratory PosterSymposia and Activities

DTIC Science & Technology

2018-04-12

ARL-SR-0394•APR 2018 US Army Research Laboratory 2nd Annual Postdoc Research Day: US Army Research Laboratory Poster Symposia and Activities by...Do not return it to the originator. ARL-SR-0394•APR 2018 US Army Research Laboratory 2nd Annual Postdoc Research Day: US Army Research Laboratory...Poster Symposia and Activities by Efraín Hernández–Rivera Weapons and Materials Research Directorate, ARL Julia Cline Oak Ridge Institute for Science and

Using Independent Research Projects to Foster Learning in the Comparative Vertebrate Anatomy Laboratory

ERIC Educational Resources Information Center

Ghedotti, Michael J.; Fielitz, Christopher; Leonard, Daniel J.

2005-01-01

This paper presents a teaching methodology involving an independent research project component for use in undergraduate Comparative Vertebrate Anatomy laboratory courses. The proposed project introduces cooperative, active learning in a research context to comparative vertebrate anatomy. This project involves pairs or groups of three students…

Research Opportunities for Undergraduate Students at Storm Peak Laboratory

NASA Astrophysics Data System (ADS)

Vargas, W.; Hallar, G.

2009-12-01

GRASP (Geoscience Research at Storm Peak) is a program providing field research experiences for a diverse group of undergraduate students. GRASP is funded by the National Science Foundation. Its mission is to recruit students from underrepresented groups within the geoscience community allowing students to work and live at the Storm Peak Laboratory (SPL). Data previously collected at the facility forms the basis for continuing research projects that addresses climate change, atmospheric pollution, and cloud formation. Prior to arriving at SPL, students travel to the National Center for Atmospheric Research (NCAR) to learn about supercomputing, mathematical modeling, and scientific visualization. GRASP participants met at the campus of Howard University for a reunion workshop and presented their results in November 2008. This poster illustrates the given task and methods used to analyze an increased concentration of organic carbon detected between April 4 and 5, 2008 at SPL located at the summit of Mt. Warner in Steamboat Springs, Colorado at an elevation of 3,202 meters.

Design and Calibration of the US Army Research Laboratory (ARL) Closed Loop Laboratory Radio Frequency (RF) Propagation Section

DTIC Science & Technology

2016-10-01

ARL-TR-7860 ● OCT 2016 US Army Research Laboratory Design and Calibration of the US Army Research Laboratory (ARL) Closed Loop ...ARL-TR-7860 ● OCT 2016 US Army Research Laboratory Design and Calibration of the US Army Research Laboratory (ARL) Closed Loop Laboratory...Design and Calibration of the US Army Research Laboratory (ARL) Closed Loop Laboratory Radio Frequency (RF) Propagation Section 5a. CONTRACT NUMBER

Stirling laboratory research engine survey report

NASA Technical Reports Server (NTRS)

Anderson, J. W.; Hoehn, F. W.

1979-01-01

As one step in expanding the knowledge relative to and accelerating the development of Stirling engines, NASA, through the Jet Propulsion Laboratory (JPL), is sponsoring a program which will lead to a versatile Stirling Laboratory Research Engine (SLRE). An objective of this program is to lay the groundwork for a commercial version of this engine. It is important to consider, at an early stage in the engine's development, the needs of the potential users so that the SLRE can support the requirements of educators and researchers in academic, industrial, and government laboratories. For this reason, a survey was performed, the results of which are described.

Artist's Concept of NASA's Propulsion Research Laboratory

NASA Technical Reports Server (NTRS)

2002-01-01

A new, world-class laboratory for research into future space transportation technologies is under construction at the Marshall Space Flight Center (MSFC) in Huntsville, AL. The state-of-the-art Propulsion Research Laboratory will serve as a leading national resource for advanced space propulsion research. Its purpose is to conduct research that will lead to the creation and development of irnovative propulsion technologies for space exploration. The facility will be the epicenter of the effort to move the U.S. space program beyond the confines of conventional chemical propulsion into an era of greatly improved access to space and rapid transit throughout the solar system. The Laboratory is designed to accommodate researchers from across the United States, including scientists and engineers from NASA, the Department of Defense, the Department of Energy, universities, and industry. The facility, with 66,000 square feet of useable laboratory space, will feature a high degree of experimental capability. Its flexibility will allow it to address a broad range of propulsion technologies and concepts, such as plasma, electromagnetic, thermodynamic, and propellantless propulsion. An important area of emphasis will be development and utilization of advanced energy sources, including highly energetic chemical reactions, solar energy, and processes based on fission, fusion, and antimatter. The Propulsion Research Laboratory is vital for developing the advanced propulsion technologies needed to open up the space frontier, and will set the stage of research that could revolutionize space transportation for a broad range of applications.

Optics research at the U.S. Naval Research Laboratory.

PubMed

Hoffman, Craig; Giallorenzi, T G; Slater, Leo B

2015-11-01

The Naval Research Laboratory (NRL) was established in Washington, DC in 1923 and is the corporate laboratory for the U.S. Navy and Marine Corps. Today NRL is a world-class research institution conducting a broad program of research and development (R&D), including many areas of optical science and technology. NRL is conducting cutting-edge R&D programs to explore new scientific areas to enable unprecedented Navy capabilities as well as improving current technologies to increase the effectiveness of Navy and other Department of Defense systems. This paper provides a broad overview of many of NRL's achievements in optics. Some of the remaining articles in this feature issue will discuss NRL's most recent research in individual areas, while other articles will present more detailed historical perspectives of NRL's research concerning particular scientific topics.

Research and the planned Space Experiment Research and Processing Laboratory

NASA Technical Reports Server (NTRS)

2000-01-01

Researchers perform tests at Kennedy Space Center. New facilities for such research will be provided at the Space Experiment Research Procession Laboratory (SERPL). The SERPL is a planned 100,000-square-foot laboratory that will provide expanded and upgraded facilities for hosting International Space Station experiment processing. In addition, it will provide better support for other biological and life sciences payload processing at KSC. It will serve as a magnet facility for a planned 400-acre Space Station Commerce Park.

Customized laboratory information management system for a clinical and research leukemia cytogenetics laboratory.

PubMed

Bakshi, Sonal R; Shukla, Shilin N; Shah, Pankaj M

2009-01-01

We developed a Microsoft Access-based laboratory management system to facilitate database management of leukemia patients referred for cytogenetic tests in regards to karyotyping and fluorescence in situ hybridization (FISH). The database is custom-made for entry of patient data, clinical details, sample details, cytogenetics test results, and data mining for various ongoing research areas. A number of clinical research laboratoryrelated tasks are carried out faster using specific "queries." The tasks include tracking clinical progression of a particular patient for multiple visits, treatment response, morphological and cytogenetics response, survival time, automatic grouping of patient inclusion criteria in a research project, tracking various processing steps of samples, turn-around time, and revenue generated. Since 2005 we have collected of over 5,000 samples. The database is easily updated and is being adapted for various data maintenance and mining needs.

A 13-Week Research-Based Biochemistry Laboratory Curriculum

ERIC Educational Resources Information Center

Lefurgy, Scott T.; Mundorff, Emily C.

2017-01-01

Here, we present a 13-week research-based biochemistry laboratory curriculum designed to provide the students with the experience of engaging in original research while introducing foundational biochemistry laboratory techniques. The laboratory experience has been developed around the directed evolution of an enzyme chosen by the instructor, with…

The impact of collaborative groups versus individuals in undergraduate inquiry-based astronomy laboratory learning exercises

NASA Astrophysics Data System (ADS)

Sibbernsen, Kendra J.

One of the long-standing general undergraduate education requirements common to many colleges and universities is a science course with a laboratory experience component. One of the objectives frequently included in the description of most of these courses is that a student will understand the nature and processes of scientific inquiry. However, recent research has shown that learners in traditional undergraduate science laboratory environments are not developing a sufficiently meaningful understanding of scientific inquiry. Recently, astronomy laboratory activities have been developed that intentionally scaffold a student from guided activities to open inquiry ones and preliminary results show that these laboratories are successful for supporting students to understand the nature of scientific inquiry (Slater, S., Slater, T. F., & Shaner, 2008). This mixed-method quasi-experimental study was designed to determine how students in an undergraduate astronomy laboratory increase their understanding of inquiry working in relative isolation compared to working in small collaborative learning groups. The introductory astronomy laboratory students in the study generally increased their understanding of scientific inquiry over the course of the semester and this held true similarly for students working in groups and students working individually in the laboratories. This was determined by the examining the change in responses from the pretest to the posttest administration of the Views of Scientific Inquiry (VOSI) survey, the increase in scores on laboratory exercises, and observations from the instructor. Because the study was successful in determining that individuals in the astronomy laboratory do as well at understanding inquiry as those who complete their exercises in small groups, it would be appropriate to offer these inquiry-based exercises in an online format.

Sandia National Laboratories: Research

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

A research update for southeast poultry research laboratory

USDA-ARS?s Scientific Manuscript database

The Southeast Poultry Research Laboratory continues with their modernization plan. The 35% architectural drawings have been completed and the project is currently out for bid for the completion of the design and building of the new facility. Research activities in the Exotic and Emerging Avian Vir...

Adaptive Training and Education Research at the US Army Research Laboratory: Bibliography (2016-2017)

DTIC Science & Technology

2018-03-05

Validation suite. Synthetic training environments. Service orientated architecture. Citation: Robson, E., Ray, F., Sinatra, A. M., & Sinatra, A. M. (2017...ARL-SR-0393 ● MAR 2018 US Army Research Laboratory Adaptive Training and Education Research at the US Army Research Laboratory... Training and Education Research at the US Army Research Laboratory: Bibliography (2016–2017) by Robert A Sottilare Human Research and

Research and Development. Laboratory Activities.

ERIC Educational Resources Information Center

Gallaway, Ann, Ed.

Research and Development is a laboratory-oriented course that includes the appropriate common essential elements for industrial technology education plus concepts and skills related to research and development. This guide provides teachers of the course with learning activities for secondary students. Introductory materials include an…

Supercharger Research at the Aircraft Engine Research Laboratory

NASA Image and Video Library

1944-01-21

A researcher in the Supercharger Research Division at the National Advisory Committee for Aeronautics (NACA) Aircraft Engine Research Laboratory measures the blade thickness on a supercharger. Superchargers were developed at General Electric used to supply additional air to reciprocating engines. The extra air resulted in increased the engine’s performance, particularly at higher altitudes. The Aircraft Engine Research Laboratory had an entire division dedicated to superchargers during World War II. General Electric developed the supercharger in response to a 1917 request from the NACA to develop a device to enhance high-altitude flying. The supercharger pushed larger volumes of air into the engine manifold. The extra oxygen allowed the engine to operate at its optimal sea-level rating even when at high altitudes. Thus, the aircraft could maintain its climb rate, maneuverability and speed as it rose higher into the sky. NACA work on the supercharger ceased after World War II due to the arrival of the turbojet engine. The Supercharger Research Division was disbanded in October 1945 and reconstituted as the Compressor and Turbine Division.

Laboratory directed research and development program, FY 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-02-01

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab) Laboratory Directed Research and Development Program FY 1996 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the projects supported and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The Berkeley Lab LDRD program is a critical tool for directing the Laboratory`s forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program provides themore » resources for Berkeley Lab scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also advances the Laboratory`s core competencies, foundations, and scientific capability, and permits exploration of exciting new opportunities. Areas eligible for support include: (1) Work in forefront areas of science and technology that enrich Laboratory research and development capability; (2) Advanced study of new hypotheses, new experiments, and innovative approaches to develop new concepts or knowledge; (3) Experiments directed toward proof of principle for initial hypothesis testing or verification; and (4) Conception and preliminary technical analysis to explore possible instrumentation, experimental facilities, or new devices.« less

A Research-Based Laboratory Course Designed to Strengthen the Research-Teaching Nexus

ERIC Educational Resources Information Center

Parra, Karlett J.; Osgood, Marcy P.; Pappas, Donald L., Jr.

2010-01-01

We describe a 10-week laboratory course of guided research experiments thematically linked by topic, which had an ultimate goal of strengthening the undergraduate research-teaching nexus. This undergraduate laboratory course is a direct extension of faculty research interests. From DNA isolation, characterization, and mutagenesis, to protein…

Perspectives from Former Executives of the DOD Corporate Research Laboratories

DTIC Science & Technology

2009-03-01

Research Laboratory (NRL) in Washington, DC; and the Air Force Research Laboratory ( AFRL ) in Dayton, Ohio respectively. These individuals are: John Lyons...13 Vincent Russo and the Air Force Research Laboratory The Air Force Research Laboratory ( AFRL ) was activated in 1997. Prior to the creation of... AFRL , the Air Force conducted its research at four major

A Research Update for Southeast Poultry Research Laboratory

USDA-ARS?s Scientific Manuscript database

The Southeast Poultry Research Laboratory continues with their modernization plan. The 35% architectural drawings have been completed and the project is currently out for bid for the completion of the design and building of the new facility. Research activities include responding to the H7N9 highl...

41 CFR 101-25.109 - Laboratory and research equipment.

Code of Federal Regulations, 2011 CFR

2011-07-01

... equipped and/or used for scientific research, testing, or analysis, except clinical laboratories operating... 41 Public Contracts and Property Management 2 2011-07-01 2007-07-01 true Laboratory and research...-General Policies § 101-25.109 Laboratory and research equipment. (a) This section prescribes controls for...

Sandia National Laboratories: Research: Research Foundations: Nanodevices

Science.gov Websites

; Technology Defense Systems & Assessments About Defense Systems & Assessments Program Areas Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

NASA Langley Research Center's Simulation-To-Flight Concept Accomplished through the Integration Laboratories of the Transport Research Facility

NASA Technical Reports Server (NTRS)

Martinez, Debbie; Davidson, Paul C.; Kenney, P. Sean; Hutchinson, Brian K.

2004-01-01

The Flight Simulation and Software Branch (FSSB) at NASA Langley Research Center (LaRC) maintains the unique national asset identified as the Transport Research Facility (TRF). The TRF is a group of facilities and integration laboratories utilized to support the LaRC's simulation-to-flight concept. This concept incorporates common software, hardware, and processes for both groundbased flight simulators and LaRC s B-757-200 flying laboratory identified as the Airborne Research Integrated Experiments System (ARIES). These assets provide Government, industry, and academia with an efficient way to develop and test new technology concepts to enhance the capacity, safety, and operational needs of the ever-changing national airspace system. The integration of the TRF enables a smooth continuous flow of the research from simulation to actual flight test.

Automated cognitive testing of monkeys in social groups yields results comparable to individual laboratory-based testing.

PubMed

Gazes, Regina Paxton; Brown, Emily Kathryn; Basile, Benjamin M; Hampton, Robert R

2013-05-01

Cognitive abilities likely evolved in response to specific environmental and social challenges and are therefore expected to be specialized for the life history of each species. Specialized cognitive abilities may be most readily engaged under conditions that approximate the natural environment of the species being studied. While naturalistic environments might therefore have advantages over laboratory settings for cognitive research, it is difficult to conduct certain types of cognitive tests in these settings. We implemented methods for automated cognitive testing of monkeys (Macaca mulatta) in large social groups (Field station) and compared the performance to that of laboratory-housed monkeys (Laboratory). The Field station animals shared access to four touch-screen computers in a large naturalistic social group. Each Field station subject had an RFID chip implanted in each arm for computerized identification and individualized assignment of cognitive tests. The Laboratory group was housed and tested in a typical laboratory setting, with individual access to testing computers in their home cages. Monkeys in both groups voluntarily participated at their own pace for food rewards. We evaluated performance in two visual psychophysics tests, a perceptual classification test, a transitive inference test, and a delayed matching-to-sample memory test. Despite the differences in housing, social environment, age, and sex, monkeys in the two groups performed similarly in all tests. Semi-free ranging monkeys living in complex social environments are therefore viable subjects for cognitive testing designed to take advantage of the unique affordances of naturalistic testing environments.

Automated cognitive testing of monkeys in social groups yields results comparable to individual laboratory based testing

PubMed Central

Gazes, Regina Paxton; Brown, Emily Kathryn; Basile, Benjamin M.; Hampton, Robert R.

2013-01-01

Cognitive abilities likely evolved in response to specific environmental and social challenges and are therefore expected to be specialized for the life history of each species. Specialized cognitive abilities may be most readily engaged under conditions that approximate the natural environment of the species being studied. While naturalistic environments might therefore have advantages over laboratory settings for cognitive research, it is difficult to conduct certain types of cognitive tests in these settings. We implemented methods for automated cognitive testing of monkeys (Macaca mulatta) in large social groups (Field station) and compared the performance to that of laboratory housed monkeys (Laboratory). The Field station animals shared access to four touch screen computers in a large naturalistic social group. Each Field station subject had an RFID chip implanted in each arm for computerized identification and individualized assignment of cognitive tests. The Laboratory group was housed and tested in a typical laboratory setting, with individual access to testing computers in their home cages. Monkeys in both groups voluntarily participated at their own pace for food rewards. We evaluated performance in two visual psychophysics tests, a perceptual classification test, a transitive inference test, and a delayed matching to sample memory test. Despite differences in housing, social environment, age, and sex, monkeys in the two groups performed similarly in all tests. Semi-free ranging monkeys living in complex social environments are therefore viable subjects for cognitive testing designed to take advantage of the unique affordances of naturalistic testing environments. PMID:23263675

Laboratory Animal Technician | Center for Cancer Research

Cancer.gov

PROGRAM DESCRIPTION The Laboratory Animal Sciences Program (LASP) provides exceptional quality animal care and technical support services for animal research performed at the National Cancer Institute at the Frederick National Laboratory for Cancer Research. LASP executes this mission by providing a broad spectrum of state-of-the-art technologies and services that are focused

Earth Resources Laboratory research and technology

NASA Technical Reports Server (NTRS)

1983-01-01

The accomplishments of the Earth Resources Laboratory's research and technology program are reported. Sensors and data systems, the AGRISTARS project, applied research and data analysis, joint research projects, test and evaluation studies, and space station support activities are addressed.

Stirling Laboratory Research Engine: Preprototype configuration report

NASA Technical Reports Server (NTRS)

Hoehn, F. W.

1982-01-01

The concept of a simple Stirling research engine that could be used by industrial, university, and government laboratories was studied. The conceptual and final designs, hardware fabrication and the experimental validation of a preprototype stirling laboratory research engine (SLRE) were completed. Also completed was a task to identify the potential markets for research engines of this type. An analytical effort was conducted to provide a stirling cycle computer model. The versatile engine is a horizontally opposed, two piston, single acting stirling engine with a split crankshaft drive mechanism; special instrumentation is installed at all component interfaces. Results of a thermodynamic energy balance for the system are reported. Also included are the engine performance results obtained over a range of speeds, working pressures, phase angles and gas temperatures. The potential for a stirling research engine to support the laboratory requirements of educators and researchers was demonstrated.

Visitor's Guide | Frederick National Laboratory for Cancer Research

Cancer.gov

The Frederick National Laboratory for Cancer Research headquarters are located at the Advanced Technology and Research Facility (ATRF), located at 8560 Progress Drive, Frederick Maryland. Additional offices and laboratories are locatedon the NC

The Columbia River Research Laboratory

USGS Publications Warehouse

Maule, Alec

2005-01-01

The U.S. Geological Survey's Columbia River Research Laboratory (CRRL) was established in 1978 at Cook, Washington, in the Columbia River Gorge east of Portland, Oregon. The CRRL, as part of the Western Fisheries Research Center, conducts research on fishery issues in the Columbia River Basin. Our mission is to: 'Serve the public by providing scientific information to support the stewardship of our Nation's fish and aquatic resources...by conducting objective, relevant research'.

41 CFR 109-25.109 - Laboratory and research equipment.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Laboratory and research... PROCUREMENT 25-GENERAL 25.1-General Policies § 109-25.109 Laboratory and research equipment. The provisions of 41 CFR 101-25.109 and this section apply to laboratory and research equipment in the possession of...

Crime Laboratory Proficiency Testing Research Program.

ERIC Educational Resources Information Center

Peterson, Joseph L.; And Others

A three-year research effort was conducted to design a crime laboratory proficiency testing program encompassing the United States. The objectives were to: (1) determine the feasibility of preparation and distribution of different classes of physical evidence; (2) assess the accuracy of criminalistics laboratories in the processing of selected…

Laboratory Directed Research and Development FY2001 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Al-Ayat, R

2002-06-20

Established by Congress in 1991, the Laboratory Directed Research and Development (LDRD) Program provides the Department of Energy (DOE)/National Nuclear Security Administration (NNSA) laboratories, like Lawrence Livermore National Laboratory (LLNL or the Laboratory), with the flexibility to invest up to 6% of their budget in long-term, high-risk, and potentially high payoff research and development (R&D) activities to support the DOE/NNSA's national security missions. By funding innovative R&D, the LDRD Program at LLNL develops and extends the Laboratory's intellectual foundations and maintains its vitality as a premier research institution. As proof of the Program's success, many of the research thrusts thatmore » started many years ago under LDRD sponsorship are at the core of today's programs. The LDRD Program, which serves as a proving ground for innovative ideas, is the Laboratory's most important single resource for fostering excellent science and technology for today's needs and tomorrow's challenges. Basic and applied research activities funded by LDRD enhance the Laboratory's core strengths, driving its technical vitality to create new capabilities that enable LLNL to meet DOE/NNSA's national security missions. The Program also plays a key role in building a world-class multidisciplinary workforce by engaging the Laboratory's best researchers, recruiting its future scientists and engineers, and promoting collaborations with all sectors of the larger scientific community.« less

Summer Research Program (1992). Graduate Student Research Program (GSRP) Reports. Volume 8. Phillips Laboratory.

DTIC Science & Technology

1992-12-28

Research Program Starfire Optical Range, Phillips Laboratory /LITE Kirtland Air Force Base, Albuquerque, NM 87117 Sponsored by: Air ... Phillips Laboratory Sponsored by: Air Force Office of Scientific Research Kirtland Air Force Base, Albuquerque, New Mexico September, 1992 18-1 PROGRESS...Report for: Summer Research Program Phillips Laboratory Sponsored by: Air

Developing a Collaborative Agenda for Humanities and Social Scientific Research on Laboratory Animal Science and Welfare.

PubMed

Davies, Gail F; Greenhough, Beth J; Hobson-West, Pru; Kirk, Robert G W; Applebee, Ken; Bellingan, Laura C; Berdoy, Manuel; Buller, Henry; Cassaday, Helen J; Davies, Keith; Diefenbacher, Daniela; Druglitrø, Tone; Escobar, Maria Paula; Friese, Carrie; Herrmann, Kathrin; Hinterberger, Amy; Jarrett, Wendy J; Jayne, Kimberley; Johnson, Adam M; Johnson, Elizabeth R; Konold, Timm; Leach, Matthew C; Leonelli, Sabina; Lewis, David I; Lilley, Elliot J; Longridge, Emma R; McLeod, Carmen M; Miele, Mara; Nelson, Nicole C; Ormandy, Elisabeth H; Pallett, Helen; Poort, Lonneke; Pound, Pandora; Ramsden, Edmund; Roe, Emma; Scalway, Helen; Schrader, Astrid; Scotton, Chris J; Scudamore, Cheryl L; Smith, Jane A; Whitfield, Lucy; Wolfensohn, Sarah

2016-01-01

Improving laboratory animal science and welfare requires both new scientific research and insights from research in the humanities and social sciences. Whilst scientific research provides evidence to replace, reduce and refine procedures involving laboratory animals (the '3Rs'), work in the humanities and social sciences can help understand the social, economic and cultural processes that enhance or impede humane ways of knowing and working with laboratory animals. However, communication across these disciplinary perspectives is currently limited, and they design research programmes, generate results, engage users, and seek to influence policy in different ways. To facilitate dialogue and future research at this interface, we convened an interdisciplinary group of 45 life scientists, social scientists, humanities scholars, non-governmental organisations and policy-makers to generate a collaborative research agenda. This drew on methods employed by other agenda-setting exercises in science policy, using a collaborative and deliberative approach for the identification of research priorities. Participants were recruited from across the community, invited to submit research questions and vote on their priorities. They then met at an interactive workshop in the UK, discussed all 136 questions submitted, and collectively defined the 30 most important issues for the group. The output is a collaborative future agenda for research in the humanities and social sciences on laboratory animal science and welfare. The questions indicate a demand for new research in the humanities and social sciences to inform emerging discussions and priorities on the governance and practice of laboratory animal research, including on issues around: international harmonisation, openness and public engagement, 'cultures of care', harm-benefit analysis and the future of the 3Rs. The process outlined below underlines the value of interdisciplinary exchange for improving communication across

Developing a Collaborative Agenda for Humanities and Social Scientific Research on Laboratory Animal Science and Welfare

PubMed Central

Davies, Gail F.; Greenhough, Beth J; Hobson-West, Pru; Kirk, Robert G. W.; Applebee, Ken; Bellingan, Laura C.; Berdoy, Manuel; Buller, Henry; Cassaday, Helen J.; Davies, Keith; Diefenbacher, Daniela; Druglitrø, Tone; Escobar, Maria Paula; Friese, Carrie; Herrmann, Kathrin; Hinterberger, Amy; Jarrett, Wendy J.; Jayne, Kimberley; Johnson, Adam M.; Johnson, Elizabeth R.; Konold, Timm; Leach, Matthew C.; Leonelli, Sabina; Lewis, David I.; Lilley, Elliot J.; Longridge, Emma R.; McLeod, Carmen M.; Miele, Mara; Nelson, Nicole C.; Ormandy, Elisabeth H.; Pallett, Helen; Poort, Lonneke; Pound, Pandora; Ramsden, Edmund; Roe, Emma; Scalway, Helen; Schrader, Astrid; Scotton, Chris J.; Scudamore, Cheryl L.; Smith, Jane A.; Whitfield, Lucy; Wolfensohn, Sarah

2016-01-01

Improving laboratory animal science and welfare requires both new scientific research and insights from research in the humanities and social sciences. Whilst scientific research provides evidence to replace, reduce and refine procedures involving laboratory animals (the ‘3Rs’), work in the humanities and social sciences can help understand the social, economic and cultural processes that enhance or impede humane ways of knowing and working with laboratory animals. However, communication across these disciplinary perspectives is currently limited, and they design research programmes, generate results, engage users, and seek to influence policy in different ways. To facilitate dialogue and future research at this interface, we convened an interdisciplinary group of 45 life scientists, social scientists, humanities scholars, non-governmental organisations and policy-makers to generate a collaborative research agenda. This drew on methods employed by other agenda-setting exercises in science policy, using a collaborative and deliberative approach for the identification of research priorities. Participants were recruited from across the community, invited to submit research questions and vote on their priorities. They then met at an interactive workshop in the UK, discussed all 136 questions submitted, and collectively defined the 30 most important issues for the group. The output is a collaborative future agenda for research in the humanities and social sciences on laboratory animal science and welfare. The questions indicate a demand for new research in the humanities and social sciences to inform emerging discussions and priorities on the governance and practice of laboratory animal research, including on issues around: international harmonisation, openness and public engagement, ‘cultures of care’, harm-benefit analysis and the future of the 3Rs. The process outlined below underlines the value of interdisciplinary exchange for improving communication across

Research Laboratories and Centers Fact Sheet

EPA Pesticide Factsheets

The Office of Research and Development is the research arm of the U.S. Environmental Protection Agency. It has three national laboratories and four national centers located in 14 facilities across the country.

Frederick National Laboratory and Georgetown University Launch Research and Education Collaboration | Frederick National Laboratory for Cancer Research

Cancer.gov

FREDERICK, Md. -- A new collaboration established between Georgetown University and the Frederick National Laboratory for Cancer Research aims to expand both institutions’ research and training missions in the biomedical sciences. Representatives f

Laboratory-directed research and development: FY 1996 progress report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vigil, J.; Prono, J.

1997-05-01

This report summarizes the FY 1996 goals and accomplishments of Laboratory-Directed Research and Development (LDRD) projects. It gives an overview of the LDRD program, summarizes work done on individual research projects, and provides an index to the projects` principal investigators. Projects are grouped by their LDRD component: Individual Projects, Competency Development, and Program Development. Within each component, they are further divided into nine technical disciplines: (1) materials science, (2) engineering and base technologies, (3) plasmas, fluids, and particle beams, (4) chemistry, (5) mathematics and computational sciences, (6) atomic and molecular physics, (7) geoscience, space science, and astrophysics, (8) nuclear andmore » particle physics, and (9) biosciences.« less

Laboratory Directed Research and Development FY-15 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pillai, Rekha Sukamar

The Laboratory Directed Research and Development (LDRD) Program at Idaho National Laboratory (INL) reports its status to the U.S. Department of Energy (DOE) by March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the laboratory director broad flexibility for program implementation. LDRD funds are obtained through a charge to all INL programs. This report includes summaries of all INL LDRD research activities supported during Fiscal Year (FY) 2015.

Laboratory Directed Research and Development FY-10 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dena Tomchak

2011-03-01

The FY 2010 Laboratory Directed Research and Development (LDRD) Annual Report is a compendium of the diverse research performed to develop and ensure the INL's technical capabilities can support the future DOE missions and national research priorities. LDRD is essential to the INL -- it provides a means for the laboratory to pursue novel scientific and engineering research in areas that are deemed too basic or risky for programmatic investments. This research enhances technical capabilities at the laboratory, providing scientific and engineering staff with opportunities for skill building and partnership development.

Nano-G research laboratory for a spacecraft

NASA Technical Reports Server (NTRS)

Vonbun, Friedrich O. (Inventor); Garriott, Owen K. (Inventor)

1991-01-01

An acceleration free research laboratory is provided that is confined within a satellite but free of any physical engagement with the walls of the satellite, wherein the laboratory has adequate power, heating, cooling, and communications services to conduct basic research and development. An inner part containing the laboratory is positioned at the center-of-mass of a satellite within the satellite's outer shell. The satellite is then positioned such that its main axes are in a position parallel to its flight velocity vector or in the direction of the residual acceleration vector. When the satellite is in its desired orbit, the inner part is set free so as to follow that orbit without contacting the inside walls of the outer shell. Sensing means detect the position of the inner part with respect to the outer shell, and activate control rockets to move the outer shell; thereby, the inner part is repositioned such that it is correctly positioned at the center-of-mass of the satellite. As a consequence, all disturbing forces, such as drag forces, act on the outer shell, and the inner part containing the laboratory is shielded and is affected only by gravitational forces. Power is supplied to the inner part and to the laboratory by a balanced microwave/laser link which creates the kind of environment necessary for basic research to study critical phenomena such as the Lambda transition in helium and crystal growth, and to perform special metals and alloys research, etc.

Group-effort applied research: expanding opportunities for undergraduate research through original, class-based research projects.

PubMed

Moore, Sean D; Teter, Ken

2014-01-01

Undergraduate research clearly enriches the educational development of participating students, but these experiences are limited by the inherent inefficiency of the standard one student-one mentor model for undergraduate research. Group-effort applied research (GEAR) was developed as a strategy to provide substantial numbers of undergraduates with meaningful research experiences. The GEAR curriculum delivers concept-driven lecture material and provides hands-on training in the context of an active research project from the instructor's laboratory. Because GEAR is structured as a class, participating students benefit from intensive, supervised research training that involves a built-in network of peer support and abundant contact with faculty mentors. The class format also ensures a relatively standardized and consistent research experience. Furthermore, meaningful progress toward a research objective can be achieved more readily with GEAR than with the traditional one student-one mentor model of undergraduate research because sporadic mistakes by individuals in the class are overshadowed by the successes of the group as a whole. Three separate GEAR classes involving three distinct research projects have been offered to date. In this article, we provide an overview of the GEAR format and review some of the recurring themes for GEAR instruction. We propose GEAR can serve as a template to expand student opportunities for life science research without sacrificing the quality of the mentored research experience. © 2014 The International Union of Biochemistry and Molecular Biology.

Practice-based research networks (PBRNs) are promising laboratories for conducting dissemination and implementation research.

PubMed

Heintzman, John; Gold, Rachel; Krist, Alexander; Crosson, Jay; Likumahuwa, Sonja; DeVoe, Jennifer E

2014-01-01

Dissemination and implementation science addresses the application of research findings in varied health care settings. Despite the potential benefit of dissemination and implementation work to primary care, ideal laboratories for this science have been elusive. Practice-based research networks (PBRNs) have a long history of conducting research in community clinical settings, demonstrating an approach that could be used to execute multiple research projects over time in broad and varied settings. PBRNs also are uniquely structured and increasingly involved in pragmatic trials, a research design central to dissemination and implementation science. We argue that PBRNs and dissemination and implementation scientists are ideally suited to work together and that the collaboration of these 2 groups will yield great value for the future of primary care and the delivery of evidence-based health care. © Copyright 2014 by the American Board of Family Medicine.

Air Force Research Laboratory Sensors Directorate Leadership Legacy, 1960-2011

DTIC Science & Technology

2011-03-01

AFRL -RY-WP-TM-2011-1017 AIR FORCE RESEARCH LABORATORY SENSORS DIRECTORATE LEADERSHIP LEGACY, 1960-2011 Compiled by Raymond C. Rang...Structures Divi- sion, Space Vehicles Directorate, Air Force Research Laboratory , Kirtland AFB, N.M. 7. March 1998 - July 1999, Chief, Integration and... Research Laboratory ( AFRL ), and Deputy Director of the Sensors Direc- torate, Air Force Research

Commissioning a materials research laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

SAVAGE,GERALD A.

2000-03-28

This presentation covers the process of commissioning a new 150,000 sq. ft. research facility at Sandia National Laboratories. The laboratory being constructed is a showcase of modern design methods being built at a construction cost of less than $180 per sq. ft. This is possible in part because of the total commissioning activities that are being utilized for this project. The laboratory's unique approach to commissioning will be presented in this paper. The process will be followed through from the conceptual stage on into the actual construction portion of the laboratory. Lessons learned and cost effectiveness will be presented inmore » a manner that will be usable for others making commissioning related decisions. Commissioning activities at every stage of the design will be presented along with the attributed benefits. Attendees will hear answers to the what, when, who, and why questions associated with commissioning of this exciting project.« less

Savannah River Ecology Laboratory. Annual technical progress report of ecological research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, M.H.

1996-07-31

The Savannah River Ecology Laboratory (SREL) is a research unit of the University of Georgia (UGA). The overall mission of the Laboratory is to acquire and communicate knowledge of ecological processes and principles. SREL conducts basic and applied ecological research, as well as education and outreach programs, under a contract with the U.S. Department of Energy (DOE) at the Savannah River Site (SRS) near Aiken, South Carolina. Significant accomplishments were made during the past year in the areas of research, education and service. The Laboratory`s research mission was fulfilled with the publication of two books and 143 journal articles andmore » book chapters by faculty, technical and students, and visiting scientists. An additional three books and about 80 journal articles currently are in press. Faculty, technician and students presented 193 lectures, scientific presentations, and posters to colleges and universities, including minority institutions. Dr. J Vaun McArthur organized and conducted the Third Annual SREL Symposium on the Environment: New Concepts in Strewn Ecology: An Integrative Approach. Dr. Michael Newman conducted a 5-day course titled Quantitative Methods in Ecotoxicology, and Dr. Brian Teppen of The Advanced Analytical Center for Environmental Sciences (AACES) taught a 3-day short course titled Introduction to Molecular Modeling of Environmental Systems. Dr. I. Lehr Brisbin co-hosted a meeting of the Crocodile Special Interest Group. Dr. Rebecca Sharitz attended four symposia in Japan during May and June 1996 and conducted meetings of the Executive Committee and Board of the International Association for Ecology (ENTECOL).« less

Tree Topping Ceremony at NASA's Propulsion Research Laboratory

NASA Technical Reports Server (NTRS)

2003-01-01

A new, world-class laboratory for research into future space transportation technologies is under construction at the Marshall Space Flight Center (MSFC) in Huntsville, AL. The state-of-the-art Propulsion Research Laboratory will serve as a leading national resource for advanced space propulsion research. Its purpose is to conduct research that will lead to the creation and development of irnovative propulsion technologies for space exploration. The facility will be the epicenter of the effort to move the U.S. space program beyond the confines of conventional chemical propulsion into an era of greatly improved access to space and rapid transit throughout the solar system. The Laboratory is designed to accommodate researchers from across the United States, including scientists and engineers from NASA, the Department of Defense, the Department of Energy, universities, and industry. The facility, with 66,000 square feet of useable laboratory space, will feature a high degree of experimental capability. Its flexibility will allow it to address a broad range of propulsion technologies and concepts, such as plasma, electromagnetic, thermodynamic, and propellantless propulsion. An important area of emphasis will be development and utilization of advanced energy sources, including highly energetic chemical reactions, solar energy, and processes based on fission, fusion, and antimatter. The Propulsion Research Laboratory is vital for developing the advanced propulsion technologies needed to open up the space frontier, and will set the stage of research that could revolutionize space transportation for a broad range of applications. This photo depicts construction workers taking part in a tree topping ceremony as the the final height of the laboratory is framed. The ceremony is an old German custom of paying homage to the trees that gave their lives in preparation of the building site.

Air Force Research Laboratory, Edwards Air Force Base, CA

DTIC Science & Technology

2011-06-27

Air Force Research Laboratory (AFMC) AFRL /RZS 1 Ara Road Edwards AFB CA 93524-7013 AFRL -RZ-ED-VG-2011-269 9...SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) Air Force Research Laboratory (AFMC) AFRL /RZS 11. SPONSOR...Form 298 (Rev. 8-98) Prescribed by ANSI Std. 239.18 Air Force Research Laboratory Ed d Ai F B CA Col Mike Platt war s r orce

1995 Laboratory-Directed Research and Development Annual report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cauffman, D.P.; Shoaf, D.L.; Hill, D.A.

1995-12-31

The Laboratory-Directed Research and Development Program (LDRD) is a key component of the discretionary research conducted by Lockheed Idaho Technologies Company (Lockheed Idaho) at the Idaho National Engineering Laboratory (INEL). The threefold purpose and goal of the LDRD program is to maintain the scientific and technical vitality of the INEL, respond to and support new technical opportunities, and enhance the agility and flexibility of the national laboratory and Lockheed Idaho to address the current and future missions of the Department of Energy.

Air Force Research Laboratory’s Focused Long Term Challenges

DTIC Science & Technology

2008-04-01

Air Force Research Laboratory ( AFRL ) mission is to provide support to the Air Force (AF) and the warfighters with... Air Force Research Laboratory’s Focused Long Term Challenges Leo J Rose Munitions Directorate, Air Force Research Laboratory , 101 W Eglin Blvd...This technology vision, which was born in our Air Force Research Laboratory , builds on the Air Force’s traditional kill

[Osaka Medical Laboratory ISO15189 Study Group: History and Future Prospects of the Group].

PubMed

Iguchi, Ken

2016-02-01

The IS015189 "Medical laboratories: Specific requirements regarding quality and competence" is an international standard issued by the International Organization for Standardization (ISO) in February 2003. In October 2004, pilot surveys were initiated in Japan prior to accreditation surveys scheduled to be started in 2005. In September 2005, the first ever ISO15189-accredited facility was established in Japan. With the background of limited information about and few opportunities to study ISO15189 in 2004, we established the Osaka Medical Laboratory ISO15189 Study Group as a unique association that anyone interested in the ISO is able to join. Approximately 900 people have participated in group meetings, which have been held a total of 11 times. Thus, our group has played a major role in ISO development in Japan. To date, approximately 100 facilities have been ISO15189-accredited in Japan, suggesting the need to take new steps regarding its accreditation. As our group has achieved our initial objective, we are planning to work towards taking new steps, such as interaction with accredited facilities.

Nanoscience and Technology at the Air Force Research Laboratory (AFRL)

DTIC Science & Technology

2005-05-01

AIR FORCE RESEARCH LABORATORY ( AFRL ) Dr. Richard A. Vaia Dr. Daniel Miracle Dr. Thomas Cruse Air Force Research ...Technology At The Air Force Research Laboratory ( AFRL ) 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT...98) Prescribed by ANSI Std Z39-18 AFRL NST Overview 2 AIR FORCE RESEARCH LABORATORY VISION We defend

Nanoscience and Technology at the Air Force Research Laboratory (AFRL)

DTIC Science & Technology

2005-02-01

AIR FORCE RESEARCH LABORATORY ( AFRL ) Dr. Richard A. Vaia Dr. Daniel Miracle Dr. Thomas Cruse Air Force Research ...Technology At The Air Force Research Laboratory ( AFRL ) 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT...98) Prescribed by ANSI Std Z39-18 AFRL NST Overview 2 AIR FORCE RESEARCH LABORATORY VISION We defend

Laboratory Directed Research and Development Annual Report FY 2017

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sullivan, Kelly O.

A national laboratory must establish and maintain an environment in which creativity and innovation are encouraged and supported in order to fulfill its missions and remain viable in the long term. As such, multiprogram laboratories are given discretion to allocate a percentage of their operating budgets to support research and development projects that align to PNNL’s and DOE’s missions and support the missions of other federal agencies, including DHS, DOD, and others. DOE Order 413.2C sets forth DOE’s Laboratory Directed Research and Development (LDRD) policy and guidelines for DOE multiprogram laboratories, and it authorizes the national laboratories to allocate upmore » to 6 percent of their operating budgets to fund the program. LDRD is innovative research and development, selected by the Laboratory Director or his/her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory. The projects supported by LDRD funding all have demonstrable ties to DOE/DHS missions and may also be relevant to the missions of other federal agencies that sponsor work at the Laboratory. The program plays a key role in attracting the best and brightest scientific staff, which is needed to serve the highest priority DOE mission objectives. Individual project reports comprise the bulk of this LDRD report. The Laboratory focuses its LDRD research on scientific assets that often address more than one scientific discipline.« less

Laboratory Directed Research and Development Annual Report FY 2016

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sullivan, Kelly O.

A national laboratory must establish and maintain an environment in which creativity and innovation are encouraged and supported in order to fulfill its missions and remain viable in the long term. As such, multiprogram laboratories are given discretion to allocate a percentage of their operating budgets to support research and development projects that align to PNNL’s and DOE’s missions and support the missions of other federal agencies, including DHS, DOD, and others. DOE Order 413.2C sets forth DOE’s Laboratory Directed Research and Development (LDRD) policy and guidelines for DOE multiprogram laboratories, and it authorizes the national laboratories to allocate upmore » to 6 percent of their operating budgets to fund the program. LDRD is innovative research and development, selected by the Laboratory Director or his/her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory. The projects supported by LDRD funding all have demonstrable ties to DOE/DHS missions and may also be relevant to the missions of other federal agencies that sponsor work at the Laboratory. The program plays a key role in attracting the best and brightest scientific staff, which is needed to serve the highest priority DOE mission objectives. Individual project reports comprise the bulk of this LDRD report. The Laboratory focuses its LDRD research on scientific assets that often address more than one scientific discipline.« less

Summer Research Program (1992). Summer Faculty Research Program (SFRP) Reports. Volume 3. Phillips Laboratory.

DTIC Science & Technology

1992-12-28

Phillips Laboratory Kirtland Air Force Base NM 87117-6008 Sponsored by: Air Force Office of Scientific Research Bolling Air Force Base...Zindel, D.: 1963, Z. Astrophys. 57, 82. 29-13 FINAL REPORT SUMMER FACULTY RESEARCH PROGRAM AT PHILLIPS LABORATORY KIRTLAND AIR FORCE BASE...Program Phillips Laboratory Sponsored by: Air Force Office of Scientific

Sandia National Laboratories: Research: Biodefense

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

Sandia National Laboratories: Research: Bioscience

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

Research and the planned Space Experiment Research and Processing Laboratory

NASA Technical Reports Server (NTRS)

2000-01-01

Original photo and caption dated October 8, 1991: 'Plant researchers Neil Yorio and Lisa Ruffe prepare to harvest a crop of Waldann's Green Lettuce from KSC's Biomass Production Chamber (BPC). KSC researchers have grown several different crops in the BPC to determine which plants will better produce food, water and oxygen on long-duration space missions.' Their work is an example of the type of life sciences research that will be conducted at the Space Experiment Research Procession Laboratory (SERPL). The SERPL is a planned 100,000-square-foot laboratory that will provide expanded and upgraded facilities for hosting International Space Station experiment processing. In addition, it will provide better support for other biological and life sciences payload processing at KSC. It will serve as a magnet facility for a planned 400-acre Space Station Commerce Park.

Research and the planned Space Experiment Research and Processing Laboratory

NASA Technical Reports Server (NTRS)

2000-01-01

Original photo and caption dated October 8, 1991: 'Plant researchers Lisa Ruffe and Neil Yorio prepare to harvest a crop of Waldann's Green Lettuce from KSC's Biomass Production Chamber (BPC). KSC researchers have grown several different crops in the BPC to determine which plants will better produce food, water and oxygen on long-duration space missions.' Their work is an example of the type of life sciences research that will be conducted at the Space Experiment Research Procession Laboratory (SERPL). The SERPL is a planned 100,000-square-foot laboratory that will provide expanded and upgraded facilities for hosting International Space Station experiment processing. In addition, it will provide better support for other biological and life sciences payload processing at KSC. It will serve as a magnet facility for a planned 400-acre Space Station Commerce Park.

Idaho National Laboratory Research & Development Impacts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stricker, Nicole

Technological advances that drive economic growth require both public and private investment. The U.S. Department of Energy’s national laboratories play a crucial role by conducting the type of research, testing and evaluation that is beyond the scope of regulators, academia or industry. Examples of such work from the past year can be found in these pages. Idaho National Laboratory’s engineering and applied science expertise helps deploy new technologies for nuclear energy, national security and new energy resources. Unique infrastructure, nuclear material inventory and vast expertise converge at INL, the nation’s nuclear energy laboratory. Productive partnerships with academia, industry and governmentmore » agencies deliver high-impact outcomes. This edition of INL’s Impacts magazine highlights national and regional leadership efforts, growing capabilities, notable collaborations, and technology innovations. Please take a few minutes to learn more about the critical resources and transformative research at one of the nation’s premier applied science laboratories.« less

Senior Laboratory Animal Technician | Center for Cancer Research

Cancer.gov

PROGRAM DESCRIPTION The Laboratory Animal Sciences Program (LASP) provides exceptional quality animal care and technical support services for animal research performed at the National Cancer Institute at the Frederick National Laboratory for Cancer Research. LASP executes this mission by providing a broad spectrum of state-of-the-art technologies and services that are focused

Definition of experiments and instruments for a communication/navigation research laboratory. Volume 3: Laboratory descriptions

NASA Technical Reports Server (NTRS)

1972-01-01

The following study objectives are covered: (1) identification of major laboratory equipment; (2) systems and operations analysis in support of the laboratory design; and (3) conceptual design of the comm/nav research laboratory.

[Results from the Central Laboratory for Streptococci Research in Kiel from 1965 to 1980 - group D-streptococci (enterococci) (author's transl)].

PubMed

Hahn, G

1981-11-01

In accordance with previous papers published within a series of publications which describe the results obtained from the Central Laboratory for Streptococcal Research in Kiel (1. Survey, 2. Mastitis-Streptococci) the group of Enterococci is discussed herewith. On the basis of more than 6000 strains which are stored in our databank including all biological characteristics, the distribution of the cultural, biochemical and serological parameters is listed in percentages, and the usefulness and reliability for the identification of the enterococcal group and also the differentiation of particular species is discussed. The results are tabulated for every single species and additionally, for serologic-positive and negative strains. For example, it can be shown that a third of all Str. faecium strains are motile, that lack of growth at 45 degrees C varies between 1.1% and 31.3% and that lack of serological reaction with group D-serum between 0.9% and 70%. In a comprehensive table and flow diagram these figures result in a proposal for a simple but sufficient identification procedure on different stages (enterococci, faecalis- or faecium-group, single species) depending on the individual requirements. With regard to the incidence of enterococci in man and animals, which was presented in the first paper, the organ sources of the different species are compared now. Apart from some interesting findings it can be stated that a typical predominance of the faecalis and faecium-group resp. in man or animals cannot be confirmed. But there seems to be a relation between the species and the organ source. For example, in humans the faecium-group predominates in the respiratory tract, but in the urogenital tract the presence of Str. faecalis is seven times higher than the faecium-group. The above results may also be of interest for ecological reasons and may be important for the pathogenesis and epidemiology of this streptococcal group.

Apoptosis as the focus of an authentic research experience in a cell physiology laboratory.

PubMed

Byrd, Shere K

2016-06-01

Curriculum-embedded independent research is a high-impact teaching practice that has been shown to increase student engagement and learning. This article describes a multiweek laboratory project for an upper-division undergraduate cell physiology laboratory using apoptosis via the mitochondrial pathway as the overarching theme. Students did literature research on apoptotic agents that acted via the mitochondrial pathway. Compounds ranged from natural products such as curcumin to synthetic compounds such as etoposide. Groups of two to three students planned a series of experiments using one of three cultured cell lines that required them to 1) learn to culture cells; 2) determine treatment conditions, including apoptotic agent solubility and concentration ranges that had been reported in the literature; 3) choose two methods to validate/quantify apoptotic capacity of the reagent; and 4) attempt to "rescue" cells from undergoing apoptosis using one of several available compounds/methods. In essence, given some reagent and equipment constraints, students designed an independent experiment to highlight the effects of different apoptotic agents on cells in culture. Students presented their experimental designs as in a laboratory group meeting and their final findings as a classroom "symposium." This exercise can be adapted to many different types of laboratories with greater or lesser equipment and instrumentation constraints, incorporates several core cell physiology methods, and encourages key experimental design and critical thinking components of independent research. Copyright © 2016 The American Physiological Society.

Improving validity of informed consent for biomedical research in Zambia using a laboratory exposure intervention.

PubMed

Zulu, Joseph Mumba; Lisulo, Mpala Mwanza; Besa, Ellen; Kaonga, Patrick; Chisenga, Caroline C; Chomba, Mumba; Simuyandi, Michelo; Banda, Rosemary; Kelly, Paul

2014-01-01

Complex biomedical research can lead to disquiet in communities with limited exposure to scientific discussions, leading to rumours or to high drop-out rates. We set out to test an intervention designed to address apprehensions commonly encountered in a community where literacy is uncommon, and where complex biomedical research has been conducted for over a decade. We aimed to determine if it could improve the validity of consent. Data were collected using focus group discussions, key informant interviews and observations. We designed an intervention that exposed participants to a detailed demonstration of laboratory processes. Each group was interviewed twice in a day, before and after exposure to the intervention in order to assess changes in their views. Factors that motivated people to participate in invasive biomedical research included a desire to stay healthy because of the screening during the recruitment process, regular advice from doctors, free medical services, and trust in the researchers. Inhibiting factors were limited knowledge about samples taken from their bodies during endoscopic procedures, the impact of endoscopy on the function of internal organs, and concerns about the use of biomedical samples. The belief that blood can be used for Satanic practices also created insecurities about drawing of blood samples. Further inhibiting factors included a fear of being labelled as HIV positive if known to consult heath workers repeatedly, and gender inequality. Concerns about the use and storage of blood and tissue samples were overcome by a laboratory exposure intervention. Selecting a group of members from target community and engaging them in a laboratory exposure intervention could be a useful tool for enhancing specific aspects of consent for biomedical research. Further work is needed to determine the extent to which improved understanding permeates beyond the immediate group participating in the intervention.

Improving Validity of Informed Consent for Biomedical Research in Zambia Using a Laboratory Exposure Intervention

PubMed Central

Zulu, Joseph Mumba; Lisulo, Mpala Mwanza; Besa, Ellen; Kaonga, Patrick; Chisenga, Caroline C.; Chomba, Mumba; Simuyandi, Michelo; Banda, Rosemary; Kelly, Paul

2014-01-01

Background Complex biomedical research can lead to disquiet in communities with limited exposure to scientific discussions, leading to rumours or to high drop-out rates. We set out to test an intervention designed to address apprehensions commonly encountered in a community where literacy is uncommon, and where complex biomedical research has been conducted for over a decade. We aimed to determine if it could improve the validity of consent. Methods Data were collected using focus group discussions, key informant interviews and observations. We designed an intervention that exposed participants to a detailed demonstration of laboratory processes. Each group was interviewed twice in a day, before and after exposure to the intervention in order to assess changes in their views. Results Factors that motivated people to participate in invasive biomedical research included a desire to stay healthy because of the screening during the recruitment process, regular advice from doctors, free medical services, and trust in the researchers. Inhibiting factors were limited knowledge about samples taken from their bodies during endoscopic procedures, the impact of endoscopy on the function of internal organs, and concerns about the use of biomedical samples. The belief that blood can be used for Satanic practices also created insecurities about drawing of blood samples. Further inhibiting factors included a fear of being labelled as HIV positive if known to consult heath workers repeatedly, and gender inequality. Concerns about the use and storage of blood and tissue samples were overcome by a laboratory exposure intervention. Conclusion Selecting a group of members from target community and engaging them in a laboratory exposure intervention could be a useful tool for enhancing specific aspects of consent for biomedical research. Further work is needed to determine the extent to which improved understanding permeates beyond the immediate group participating in the intervention

Virtual Instruction: A Qualitative Research Laboratory Course

ERIC Educational Resources Information Center

Stadtlander, Lee M.; Giles, Martha J.

2010-01-01

Online graduate programs in psychology are becoming common; however, a concern has been whether instructors in the programs provide adequate research mentoring. One issue surrounding research mentoring is the absence of research laboratories in the virtual university. Students attending online universities often do research without peer or lab…

Current safety practices in nano-research laboratories in China.

PubMed

Zhang, Can; Zhang, Jing; Wang, Guoyu

2014-06-01

China has become a key player in the global nanotechnology field, however, no surveys have specifically examined safety practices in the Chinese nano-laboratories in depth. This study reports results of a survey of 300 professionals who work in research laboratories that handle nanomaterials in China. We recruited participants at three major nano-research laboratories (which carry out research in diverse fields such as chemistry, material science, and biology) and the nano-chemistry session of the national meeting of the Chinese Chemical Society. Results show that almost all nano-research laboratories surveyed had general safety regulations, whereas less than one third of respondents reported having nanospecific safety rules. General safety measures were in place in most surveyed nano-research laboratories, while nanospecific protective measures existed or were implemented less frequently. Several factors reported from the scientific literature including nanotoxicology knowledge gaps, technical limitations on estimating nano-exposure, and the lack of nano-occupational safety legislation may contribute to the current state of affairs. With these factors in mind and embracing the precautionary principle, we suggest strengthening or providing nanosafety training (including raising risk awareness) and establishing nanosafety guidelines in China, to better protect personnel in the nano-workplace.

Guard House at the Aircraft Engine Research Laboratory

NASA Image and Video Library

1945-08-21

A vehicle leaves the National Advisory Committee for Aeronautics (NACA) Aircraft Engine Research Laboratory on August 14, 1945. At 7 p.m. that evening President Truman announced that Japan had accepted terms for surrender and World War II was over. The end of the war brought significant changes for the laboratory. The NACA would cease its troubleshooting of military aircraft and return to research. Researchers would increase their efforts to address the new technologies that emerged during the war. The entire laboratory was reorganized in October to better investigate turbojets, ramjets, and rockets. The guard house sat on the main entrance to the laboratory off of Brookpark Road. The building was fairly small and easily crowded. In the early 1960s a new security facility was built several hundred feet beyond the original guard house. The original structure remained in place for several years but was not utilized. The subsequent structure was replaced in 2011 by a new building and entrance configuration.

Science and Technology: The Making of the Air Force Research Laboratory

DTIC Science & Technology

2000-01-01

AFRL . . . . . . . . . . . 187 11 Air Force Research Laboratory : Before and After...United States Air Force during my tenure as chief of staff—the crea - tion of the Air Force Research Laboratory ( AFRL ). As the “high technology” service...consolidate four existing laboratories into one Air Force Research Laboratory ( AFRL ) designed to lead to a more efficient and streamlined

USAF Summer Research Program - 1993 Graduate Student Research Program Final Reports, Volume 8, Phillips Laboratory

DTIC Science & Technology

1994-12-01

Research Program Phillips Laboratory Kirtland Air Force Base Albuquerque, New Mexico Sponsored by: Air ...Summer Research Program Phillips Laboratory Sponsored by. Air Force Office of Scientific Research Kirtland Air Force Base, Albuquerque, New Mexico...UNITED STATES AIR FORCE SUMMER RESEARCH PROGRAM -- 1993 SUMMER RESEARCH PROGRAM FINAL REPORTS VOLUME 8

Biological and Physical Space Research Laboratory 2002 Science Review

NASA Technical Reports Server (NTRS)

Curreri, P. A. (Editor); Robinson, M. B. (Editor); Murphy, K. L. (Editor)

2003-01-01

With the International Space Station Program approaching core complete, our NASA Headquarters sponsor, the new Code U Enterprise, Biological and Physical Research, is shifting its research emphasis from purely fundamental microgravity and biological sciences to strategic research aimed at enabling human missions beyond Earth orbit. Although we anticipate supporting microgravity research on the ISS for some time to come, our laboratory has been vigorously engaged in developing these new strategic research areas.This Technical Memorandum documents the internal science research at our laboratory as presented in a review to Dr. Ann Whitaker, MSFC Science Director, in July 2002. These presentations have been revised and updated as appropriate for this report. It provides a snapshot of the internal science capability of our laboratory as an aid to other NASA organizations and the external scientific community.

Research and the planned Space Experiment Research and Processing Laboratory

NASA Technical Reports Server (NTRS)

2000-01-01

Original photo and caption dated June 22, 1988: 'A dwarf wheat variety known as Yecoro Rojo flourishes in KSC's Biomass Production Chamber. Researchers are gathering information on the crop's ability to produce food, water and oxygen, and then remove carbon dioxide. The confined quarters associated with space travel require researchers to focus on smaller plants that yield proportionately large amounts of biomass. This wheat crop takes about 85 days to grow before harvest.' Plant experiments such as this are the type of life sciences research that will be conducted at the Space Experiment Research Procession Laboratory (SERPL). The SERPL is a planned 100,000-square-foot laboratory that will provide expanded and upgraded facilities for hosting International Space Station experiment processing. In addition, it will provide better support for other biological and life sciences payload processing at KSC. It will serve as a magnet facility for a planned 400-acre Space Station Commerce Park.

Our Story | Materials Research Laboratory at UCSB: an NSF MRSEC

Science.gov Websites

this site Materials Research Laboratory at UCSB: an NSF MRSEC logo Materials Research Laboratory at & Workshops Visitor Info Research IRG-1: Magnetic Intermetallic Mesostructures IRG 2: Polymeric Seminars Publications MRL Calendar Facilities Computing Energy Research Facility Microscopy &

The Johns Hopkins Hunterian Laboratory Philosophy: Mentoring Students in a Scientific Neurosurgical Research Laboratory.

PubMed

Tyler, Betty M; Liu, Ann; Sankey, Eric W; Mangraviti, Antonella; Barone, Michael A; Brem, Henry

2016-06-01

After over 50 years of scientific contribution under the leadership of Harvey Cushing and later Walter Dandy, the Johns Hopkins Hunterian Laboratory entered a period of dormancy between the 1960s and early 1980s. In 1984, Henry Brem reinstituted the Hunterian Neurosurgical Laboratory, with a new focus on localized delivery of therapies for brain tumors, leading to several discoveries such as new antiangiogenic agents and Gliadel chemotherapy wafers for the treatment of malignant gliomas. Since that time, it has been the training ground for 310 trainees who have dedicated their time to scientific exploration in the lab, resulting in numerous discoveries in the area of neurosurgical research. The Hunterian Neurosurgical Laboratory has been a unique example of successful mentoring in a translational research environment. The laboratory's philosophy emphasizes mentorship, independence, self-directed learning, creativity, and people-centered collaboration, while maintaining productivity with a focus on improving clinical outcomes. This focus has been served by the diverse backgrounds of its trainees, both in regard to educational status as well as culturally. Through this philosophy and strong legacy of scientific contribution, the Hunterian Laboratory has maintained a positive and productive research environment that supports highly motivated students and trainees. In this article, the authors discuss the laboratory's training philosophy, linked to the principles of adult learning (andragogy), as well as the successes and the limitations of including a wide educational range of students in a neurosurgical translational laboratory and the phenomenon of combining clinical expertise with rigorous scientific training.

USAF Summer Research Program - 1993 Summer Research Extension Program Final Reports, Volume 2, Phillips Laboratory

DTIC Science & Technology

1994-11-01

Research Extension Program Phillips Laboratory Kirtland Air Force Base Sponsored by: Air Force Office of Scientific Research Boiling Air Force Base...Program Phillips Laboratory Sponsored by: Air Force Office of Scientific Research Bolling Air Force Base, Washington, D.C. and Arkansas Tech University...Summer Research Extension Program (SREP) Phillips

Flight Research Building at the Aircraft Engine Research Laboratory

NASA Image and Video Library

1942-09-21

The Flight Research Building at the National Advisory Committee for Aeronautics (NACA) Aircraft Engine Research Laboratory is a 272- by 150-foot hangar with an internal height up to 90 feet. The hangar’s massive 37.5-foot-tall and 250-foot-long doors can be opened in sections to suit different size aircraft. The hangar has sheltered a diverse fleet of aircraft over the decades. These have ranged from World War II bombers to Cessna trainers and from supersonic fighter jets to a DC–9 airliner. At the time of this September 1942 photograph, however, the hangar was being used as an office building during the construction of the laboratory. In December of 1941, the Flight Research Building became the lab’s first functional building. Temporary offices were built inside the structure to house the staff while the other buildings were completed. The hangar offices were used for an entire year before being removed in early 1943. It was only then that the laboratory acquired its first aircraft, pilots and flight mechanics. The temporary one-story offices can be seen in this photograph inside the large sliding doors. Also note the vertical lift gate below the NACA logo. The gate was installed so that the tails of larger aircraft could pass into the hangar. The white Farm House that served as the Administration Building during construction can be seen in the distance to the left of the hangar.

Solvent use in private research laboratories in Japan: comparison with the use in public research laboratories and on production floors in industries.

PubMed

Hanada, Takaaki; Zaitsu, Ai; Kojima, Satoshi; Ukai, Hirohiko; Nagasawa, Yasuhiro; Takada, Shiro; Kawakami, Takuya; Ohashi, Fumiko; Ikeda, Masayuki

2014-01-01

Solvents used in production facility-affiliated private laboratories have been seldomly reported. This study was initiated to specify solvent use characteristics in private laboratories in comparison with the use in public research laboratories and on production floors. Elucidation of the applicability of conclusions from a public laboratory survey to private institutions is not only of scientific interest but also of practical importance. A survey on use of 47 legally stipulated organic solvents was conducted. The results were compiled for April 2011 to March 2013. Through sorting, data were available for 479 unit workplaces in private laboratories. Similar sorting for April 2012 to March 2013 was conducted for public research laboratories (e.g., national universities) and production floors (in private enterprises) to obtain 621 and 937 cases, respectively. Sampling of workroom air followed by capillary gas-chromatographic analyses for solvents was conducted in accordance with regulatory requirements. More than one solvent was usually detected in the air of private laboratories. With regard to solvent types, acetone, methyl alcohol, chloroform and hexane were prevalently used in private laboratories, and this was similar to the case of public laboratories. Prevalent use of ethyl acetate was unique to private laboratories. Toluene use was less common both in private and public laboratories. The prevalence of administrative control class 1 (i.e., an adequately controlled environment) was higher in laboratories (both private and public) than production floors. Solvent use patterns are similar in private and public laboratories, except that the use of mixtures of solvents is substantially more popular in private laboratories than in public laboratories.

US Army Research Laboratory (ARL) Robotics Collaborative Technology Alliance 2014 Capstone Experiment

DTIC Science & Technology

2016-07-01

ARL-TR-7729 ● JULY 2016 US Army Research Laboratory US Army Research Laboratory (ARL) Robotics Collaborative Technology Alliance...TR-7729 ● JULY 2016 US Army Research Laboratory US Army Research Laboratory (ARL) Robotics Collaborative Technology Alliance 2014 Capstone...National Robotics Engineering Center, Pittsburgh, PA Robert Dean, Terence Keegan, and Chip Diberardino General Dynamics Land Systems, Westminster

Laboratory Directed Research and Development Program FY 2006 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sjoreen, Terrence P

2007-04-01

The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the US Departmental of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, 'Laboratory Directed Research and Development' (April 19, 2006), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2006. The associated FY 2006 ORNL LDRD Self-Assessment (ORNL/PPA-2007/2) provides financial data about themore » FY 2006 projects and an internal evaluation of the program's management process.« less

Fish passage research: S.O. Conte Anadromous Fish Research Laboratory

USGS Publications Warehouse

Garebedian, Steve

2008-01-01

The Leetown Science Center’s S.O. Conte Anadromous Fish Research Laboratory conducts basic and applied scientific studies of fish passage and migration to define underlying principles and relationships of fish behavior and hydraulics, and to develop integrated, predictive research that can be applied to a wide range of fish passage problems.

A Survey on Faculty Perspectives on the Transition to a Biochemistry Course-Based Undergraduate Research Experience Laboratory

ERIC Educational Resources Information Center

Craig, Paul A.

2017-01-01

It will always remain a goal of an undergraduate biochemistry laboratory course to engage students hands-on in a wide range of biochemistry laboratory experiences. In 2006, our research group initiated a project for "in silico" prediction of enzyme function based only on the 3D coordinates of the more than 3800 proteins "of unknown…

Laboratory Directed Research and Development Program Assessment for FY 2008

DOE Office of Scientific and Technical Information (OSTI.GOV)

Looney, J P; Fox, K J

2008-03-31

Brookhaven National Laboratory (BNL) is a multidisciplinary Laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal Year 2008 spending was $531.6 million. There are approximately 2,800 employees, and another 4,300 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annuallymore » in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development,' April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new 'fundable' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research 'which could lead to new programs, projects, and directions' for the Laboratory. To be a premier scientific Laboratory, BNL must continuously foster groundbreaking scientific research and renew its research agenda. The competition for LDRD funds stimulates Laboratory scientists to think in new and creative ways, which becomes a major factor in achieving and maintaining research excellence and a means to address National needs within the overall mission of the DOE and BNL. By fostering high-risk, exploratory research, the LDRD program helps BNL to respond new scientific opportunities

Cookstove Laboratory Research - Fiscal Year 2016 Report

EPA Science Inventory

This report provides an overview of the work conducted by the EPA cookstove laboratory research team in Fiscal Year 2016. The report describes research and activities including (1) ISO standards development, (2) capacity building for international testing and knowledge centers, ...

ECOSYSTEM RESTORATION RESEARCH THROUGH THE NATIONAL RISK MANAGEMENT RESEARCH LABORATORY (NRMRL)

EPA Science Inventory

The Ecosystem Restoration Research Program underway through ORD's National Risk Management Research Laboratory (NRMRL) has the long-term goal of providing watershed managers with "..state-of-the-science field-evaluated tools, technical guidance, and decision-support systems for s...

A STUDY OF SMALL GROUP DYNAMICS AND PRODUCTIVITY IN THE BSCS LABORATORY BLOCK PROGRAM.

ERIC Educational Resources Information Center

HURD, PAUL DEHART; ROWE, MARY BUDD

THE RELATIONSHIP BETWEEN SMALL GROUP COMPATIBILITY AND ACHIEVEMENT IN THE BIOLOGICAL SCIENCE CURRICULUM STUDY LABORATORY BLOCK PROGRAM WAS TESTED. STUDENTS IN 14 CLASSES FROM FOUR HIGH SCHOOLS WERE ASSIGNED TO FOUR-MEMBER LABORATORY GROUPS CLASSIFIED AS COMPATIBLE OR INCOMPATIBLE. GROUP CLASSIFICATION WAS VALIDATED BY OBSERVERS WHO WERE NOT AWARE…

The Air Force Research Laboratory’s In-Space Propulsion Program

DTIC Science & Technology

2015-02-01

Air Force Research Laboratory (AFMC) AFRL /RQRS 1 Ara...MONITOR’S ACRONYM(S) Air Force Research Laboratory (AFMC) AFRL /RQR 5 Pollux Drive 11. SPONSOR/MONITOR’S REPORT Edwards AFB CA 93524-7048 NUMBER(S) AFRL ...illustrate the rationale behind AFRL’s technology development strategy. INTRODUCTION The Air Force Research Laboratory ( AFRL ) is the technology

Guidance for Human Subjects Research in the National Exposure Research Laboratory

EPA Science Inventory

This document provides guidance to investigators and managers associated with the U.S. Environmental Protection Agency (EPA) Office of Research and Development (ORD)’s National Exposure Research Laboratory (NERL) on the ethical conduct, regulatory review, and approval of all huma...

HUMAN HEALTH RESEARCH IMPLEMENTATION PLAN, NATIONAL HEALTH AND ENVIRONMENTAL EFFECTS RESEARCH LABORATORY

EPA Science Inventory

The National Health and Environmental Effects Research Laboratory (NHEERL), as part of the Environmental Protection Agency's (EPA's) Office of Research and Development (ORD), is responsible for conducting research to improve the risk assessment of chemicals for potential effects ...

NASA Ames Fluid Mechanics Laboratory research briefs

NASA Technical Reports Server (NTRS)

Davis, Sanford (Editor)

1994-01-01

The Ames Fluid Mechanics Laboratory research program is presented in a series of research briefs. Nineteen projects covering aeronautical fluid mechanics and related areas are discussed and augmented with the publication and presentation output of the Branch for the period 1990-1993.

History | Frederick National Laboratory for Cancer Research

Cancer.gov

The Frederick National Laboratory for Cancer Research was established as the Frederick Cancer Research and Development Center in 1972 when about 70 acres and 67 buildings of the U.S. Army were transferred to the U.S. Department of Health and Huma

US Army Research Laboratory and University of Notre Dame Distributed Sensing: Hardware Overview

DTIC Science & Technology

2017-11-01

ARL-TR-8199 ● NOV 2017 US Army Research Laboratory US Army Research Laboratory and University of Notre Dame Distributed Sensing...US Army Research Laboratory US Army Research Laboratory and University of Notre Dame Distributed Sensing: Hardware Overview by Roger P...TITLE AND SUBTITLE US Army Research Laboratory and University of Notre Dame Distributed Sensing: Hardware Overview 5a. CONTRACT NUMBER 5b. GRANT

Freshwater findings, 1979-1982: research publications of the Environmental Research Laboratory, Duluth, Minnesota

DOE Office of Scientific and Technical Information (OSTI.GOV)

Highland, T.; Curtis, C.

1983-10-01

This report contains citations of publications for the years 1979-1982 on research conducted or supported by the Environmental Research Laboratory-Duluth. All published material has been organized into two major categories: (1) Journal Articles, Book Chapters, Proceedings, etc., and (2) EPA Research Reports. The report is organized by year with all journal articles, book chapters, proceedings, etc., for a given year appearing before the EPA research reports for the same year; within each category publications are listed alphabetically by author. Authors of the publications listed include ERL-Duluth laboratory staff members and scientists at universities, in industry, and at other facilities whomore » received research funding under the auspices of the Environmental Research Laboratory-Duluth. Limited quantities of reprints are available for those articles identified by ERL-Duluth reprint number in parentheses following the citation. These can be obtained by writing to: Librarian, ERL-Duluth, U.S. EPA, 6201 Congdon Boulevard, Duluth, MN 55804. EPA research reports can be obtained by writing to: National Technical Information Service, 5285 Port Royal Road, Springfield, VA 22151. All other articles are not available from ERL-Duluth or NTIS, but can be found in most major libraries.« less

MSU-DOE Plant Research Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-01-01

This document is the compiled progress reports of research funded through the Michigan State University/Department of Energy Plant Research Laboratory. Fourteen reports are included, covering the molecular basis of plant/microbe symbiosis, cell wall biosynthesis and proteins, gene expression, stress responses, plant hormone biosynthesis, interactions between the nuclear and organelle genomes, sensory transduction and tropisms, intracellular sorting and trafficking, regulation of lipid metabolism, molecular basis of disease resistance and plant pathogenesis, developmental biology of Cyanobacteria, and hormonal involvement in environmental control of plant growth. 320 refs., 26 figs., 3 tabs. (MHB)

Laboratory directed research and development program FY 1999

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hansen, Todd; Levy, Karin

2000-03-08

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operatemore » unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. This is the annual report on Laboratory Directed Research and Development (LDRD) program for FY99.« less

Laboratory Directed Research and Development annual report, fiscal year 1997

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-03-01

The Department of Energy Order 413.2(a) establishes DOE`s policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. As described in 413.2, LDRD is research and development of a creative and innovative nature which is selected by the Laboratory Director or his or her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory and to respond to scientific and technological opportunities in conformance with the guidelines in this Order. DOE Order 413.2 requires that each laboratory submit an annual report on its LDRD activities to the cognizant Secretarial Officer through themore » appropriate Operations Office Manager. The report provided in this document represents Pacific Northwest National Laboratory`s LDRD report for FY 1997.« less

Laboratory Directed Research and Development Program Activities for FY 2007.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Newman,L.

2007-12-31

Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal year 2007 budget was $515 million. There are about 2,600 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annuallymore » in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development', April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. In accordance this is our Annual Report in which we describe the Purpose, Approach, Technical Progress and Results, and Specific Accomplishments of all LDRD projects that received funding during Fiscal Year 2007. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new 'fundable' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research 'which could lead to new programs, projects, and directions' for the Laboratory. We explicitly indicate that research conducted under the LDRD Program should be highly innovative, and an element of high risk as to success is acceptable. In the solicitation for new proposals for Fiscal Year 2007 we especially requested innovative new projects in support of RHIC and the Light Source and

24. PHOTOCOPY OF PLAN DRAWING. Quartermaster Research and Development Laboratory, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

24. PHOTOCOPY OF PLAN DRAWING. Quartermaster Research and Development Laboratory, Natick, Mass, Climatic Building, First Floor Plan, Architectural. Drawing No. 35-07-01, Sheet 2 of 72, 1952, updated to 1985. (Source: NRDEC). - Natick Research & Development Laboratories, Climatic Chambers Building, U.S. Army Natick Research, Development & Engineering Center (NRDEC), Natick, Middlesex County, MA

25. PHOTOCOPY OF PLAN DRAWING. Quartermaster Research and Development Laboratory, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

25. PHOTOCOPY OF PLAN DRAWING. Quartermaster Research and Development Laboratory, Natick, Mass. Climatic Building, First Floor Plan, Refrigeration and Engineering. Drawing No. 35-07-01, Sheet 52 of 72, 1952. (Source: NRDEC). - Natick Research & Development Laboratories, Climatic Chambers Building, U.S. Army Natick Research, Development & Engineering Center (NRDEC), Natick, Middlesex County, MA

Laboratory Directed Research and Development FY2008 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kammeraad, J E; Jackson, K J; Sketchley, J A

The Laboratory Directed Research and Development (LDRD) Program, authorized by Congress in 1991 and administered by the Institutional Science and Technology Office at Lawrence Livermore, is our primary means for pursuing innovative, long-term, high-risk, and potentially high-payoff research that supports the full spectrum of national security interests encompassed by the missions of the Laboratory, the Department of Energy, and National Nuclear Security Administration. The accomplishments described in this annual report demonstrate the strong alignment of the LDRD portfolio with these missions and contribute to the Laboratory's success in meeting its goals. The LDRD budget of $91.5 million for fiscal yearmore » 2008 sponsored 176 projects. These projects were selected through an extensive peer-review process to ensure the highest scientific quality and mission relevance. Each year, the number of deserving proposals far exceeds the funding available, making the selection a tough one indeed. Our ongoing investments in LDRD have reaped long-term rewards for the Laboratory and the nation. Many Laboratory programs trace their roots to research thrusts that began several years ago under LDRD sponsorship. In addition, many LDRD projects contribute to more than one mission area, leveraging the Laboratory's multidisciplinary team approach to science and technology. Safeguarding the nation from terrorist activity and the proliferation of weapons of mass destruction will be an enduring mission of this Laboratory, for which LDRD will continue to play a vital role. The LDRD Program is a success story. Our projects continue to win national recognition for excellence through prestigious awards, papers published in peer-reviewed journals, and patents granted. With its reputation for sponsoring innovative projects, the LDRD Program is also a major vehicle for attracting and retaining the best and the brightest technical staff and for establishing collaborations with universities

Quality Indicators in Laboratory Medicine: from theory to practice. Preliminary data from the IFCC Working Group Project "Laboratory Errors and Patient Safety".

PubMed

Sciacovelli, Laura; O'Kane, Maurice; Skaik, Younis Abdelwahab; Caciagli, Patrizio; Pellegrini, Cristina; Da Rin, Giorgio; Ivanov, Agnes; Ghys, Timothy; Plebani, Mario

2011-05-01

The adoption of Quality Indicators (QIs) has prompted the development of tools to measure and evaluate the quality and effectiveness of laboratory testing, first in the hospital setting and subsequently in ambulatory and other care settings. While Laboratory Medicine has an important role in the delivery of high-quality care, no consensus exists as yet on the use of QIs focussing on all steps of the laboratory total testing process (TTP), and further research in this area is required. In order to reduce errors in laboratory testing, the IFCC Working Group on "Laboratory Errors and Patient Safety" (WG-LEPS) developed a series of Quality Indicators, specifically designed for clinical laboratories. In the first phase of the project, specific QIs for key processes of the TTP were identified, including all the pre-, intra- and post-analytic steps. The overall aim of the project is to create a common reporting system for clinical laboratories based on standardized data collection, and to define state-of-the-art and Quality Specifications (QSs) for each QI independent of: a) the size of organization and type of activities; b) the complexity of processes undertaken; and c) different degree of knowledge and ability of the staff. The aim of the present paper is to report the results collected from participating laboratories from February 2008 to December 2009 and to identify preliminary QSs. The results demonstrate that a Model of Quality Indicators managed as an External Quality Assurance Program can serve as a tool to monitor and control the pre-, intra- and post-analytical activities. It might also allow clinical laboratories to identify risks that lead to errors resulting in patient harm: identification and design of practices that eliminate medical errors; the sharing of information and education of clinical and laboratory teams on practices that reduce or prevent errors; the monitoring and evaluation of improvement activities.

Sandia, California Tritium Research Laboratory transition and reutilization project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garcia, T.B.

1997-02-01

This paper describes a project within Sandia National Laboratory to convert the shut down Tritium Research Laboratory into a facility which could be reused within the laboratory complex. In the process of decommissioning and decontaminating the facility, the laboratory was able to save substantial financial resources by transferring much existing equipment to other DOE facilities, and then expeditiously implementing a decontamination program which has resulted in the building being converted into laboratory space for new lab programs. This project of facility reuse has been a significant financial benefit to the laboratory.

Sandia National Laboratories: Visiting Research Scholars

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

Frederick National Laboratory Scientists to Present Advanced Technologies in Cancer Research | Frederick National Laboratory for Cancer Research

Cancer.gov

FREDERICK, Md. -- Hundreds of science and business professionals are expected to attend the second annual Technology Showcase at the Frederick National Laboratory for Cancer Research, scheduled for June 13.  The event will feature technologies bei

78 FR 70579 - Deluxe Laboratories, Inc., a Division of Deluxe Entertainment Services Group, Inc. Hollywood...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-26

...., a Division of Deluxe Entertainment Services Group, Inc. Hollywood, California; Notice of Revised... of Deluxe Laboratories, Inc., a division of Deluxe Entertainment Services Group, Inc., Hollywood... workers of Deluxe Laboratories, Inc., a division of Deluxe Entertainment Services Group, Inc., Hollywood...

The viability of establishing collaborative, reconfigurable research environments for the Human Performance Research Laboratory at NASA Ames

NASA Technical Reports Server (NTRS)

Clipson, Colin

1994-01-01

This paper will review and summarize research initiatives conducted between 1987 and 1992 at NASA Ames Research Center by a research team from the University of Michigan Architecture Research Laboratory. These research initiatives, funded by a NASA grant NAG2-635, examined the viability of establishing collaborative, reconfigurable research environments for the Human Performance Research Laboratory at NASA Ames in California. Collaborative Research Environments are envisioned as a way of enhancing the work of NASA research teams, optimizing the use of shared resources, and providing superior environments for housing research activities. The Integrated Simulation Project at NASA, Ames Human Performance Research Laboratory is one of the current realizations of this initiative.

Airborne mass spectrometers: four decades of atmospheric and space research at the Air Force research laboratory.

PubMed

Viggiano, A A; Hunton, D E

1999-11-01

Mass spectrometry is a versatile research tool that has proved to be extremely useful for exploring the fundamental nature of the earth's atmosphere and ionosphere and in helping to solve operational problems facing the Air Force and the Department of Defense. In the past 40 years, our research group at the Air Force Research Laboratory has flown quadrupole mass spectrometers of many designs on nearly 100 sounding rockets, nine satellites, three Space Shuttles and many missions of high-altitude research aircraft and balloons. We have also used our instruments in ground-based investigations of rocket and jet engine exhaust, combustion chemistry and microwave breakdown chemistry. This paper is a review of the instrumentation and techniques needed for space research, a summary of the results from many of the experiments, and an introduction to the broad field of atmospheric and space mass spectrometry in general. Copyright 1999 John Wiley & Sons, Ltd.

United States Air Force Summer Research Program -- 1993. Volume 8. Phillips Laboratory

DTIC Science & Technology

1993-12-01

Research Program Phillips Laboratory Kirtland Air Force Base Albuquerque. New Mexico Sponsored by...Best Available Copy UNITED STATES AIR FORCE SUMMER RESEARCH PROGRAM -- 1993 SUMMER RESEARCH PROGRAM FINAL REPORTS VOLUME 8 PHILLIPS LABORATORY ...Alabama Box 870344 Tuscaloosa, AL 35487-0344 Final Report for: Graduate Student Research Program Phillips Laboratory , Hanscom AFB Sponsored by: Air

Catalog of Research Abstracts, 1993: Partnership opportunities at Lawrence Berkeley Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-09-01

The 1993 edition of Lawrence Berkeley Laboratory`s Catalog of Research Abstracts is a comprehensive listing of ongoing research projects in LBL`s ten research divisions. Lawrence Berkeley Laboratory (LBL) is a major multi-program national laboratory managed by the University of California for the US Department of Energy (DOE). LBL has more than 3000 employees, including over 1000 scientists and engineers. With an annual budget of approximately $250 million, LBL conducts a wide range of research activities, many that address the long-term needs of American industry and have the potential for a positive impact on US competitiveness. LBL actively seeks to sharemore » its expertise with the private sector to increase US competitiveness in world markets. LBL has transferable expertise in conservation and renewable energy, environmental remediation, materials sciences, computing sciences, and biotechnology, which includes fundamental genetic research and nuclear medicine. This catalog gives an excellent overview of LBL`s expertise, and is a good resource for those seeking partnerships with national laboratories. Such partnerships allow private enterprise access to the exceptional scientific and engineering capabilities of the federal laboratory systems. Such arrangements also leverage the research and development resources of the private partner. Most importantly, they are a means of accessing the cutting-edge technologies and innovations being discovered every day in our federal laboratories.« less

QUALITY ASSURANCE IN RESEARCH LABORATORIES: RULES AND REASON

EPA Science Inventory

Quality Assurance in Research Laboratories: Rules and Reason

Ron Rogers, Quality Assurance and Records Manager, Environmental Carcinogenesis Division, NHEERL/ORD/US EPA, Research Triangle Park, NC, 27709

To anyone who has actively participated in research, as I have...

Air Force Research Laboratory Spacecraft Cryocooler Endurance Evaluation Facility Closing Report

NASA Astrophysics Data System (ADS)

Armstrong, J.; Martin, K. W.; Fraser, T.

2015-12-01

The Air Force Research Laboratory (AFRL) Spacecraft Component Thermal Research Group has been devoted to evaluating lifetime performance of space cryocooler technology for over twenty years. Long-life data is essential for confirming design lifetimes for space cryocoolers. Continuous operation in a simulated space environment is the only accepted method to test for degradation. AFRL has provided raw data and detailed evaluations to cryocooler developers for advancing the technology, correcting discovered deficiencies, and improving cryocooler designs. At AFRL, units of varying design and refrigeration cycles were instrumented in state-of-the-art experiment stands to provide spacelike conditions and were equipped with software data acquisition to track critical cryocooler operating parameters. This data allowed an assessment of the technology's ability to meet the desired lifetime and documented any long-term changes in performance. This paper will outline a final report of the various flight cryocoolers tested in our laboratory. The data summarized includes the seven cryocoolers tested during 2014-2015. These seven coolers have a combined total of 433,326 hours (49.5 years) of operation.

Laboratory Directed Research and Development Program FY98

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hansen, T.; Chartock, M.

1999-02-05

The Ernest Orlando Lawrence Berkeley National Laboratory (LBNL or Berkeley Lab) Laboratory Directed Research and Development Program FY 1998 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the supported projects and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The LBNL LDRD program is a critical tool for directing the Laboratory's forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program providesmore » the resources for LBNL scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also advances LBNL's core competencies, foundations, and scientific capability, and permits exploration of exciting new opportunities. All projects are work in forefront areas of science and technology. Areas eligible for support include the following: Advanced study of hypotheses, concepts, or innovative approaches to scientific or technical problems; Experiments and analyses directed toward ''proof of principle'' or early determination of the utility of new scientific ideas, technical concepts, or devices; and Conception and preliminary technical analyses of experimental facilities or devices.« less

Cookstove Laboratory Research - Fiscal Year 2016 Report ...

EPA Pesticide Factsheets

This report provides an overview of the work conducted by the EPA cookstove laboratory research team in Fiscal Year 2016. The report describes research and activities including (1) ISO standards development, (2) capacity building for international testing and knowledge centers, (3) laboratory assessments of cookstove systems, (4) journal publications, and (5) cookstove events. The U.S. Environmental Protection Agency’s (EPA’s) cookstove laboratory research program was first developed to assist the EPA-led Partnership for Clean Indoor Air and is now part of the U.S. Government’s commitment to the Global Alliance for Clean Cookstoves (the Alliance). Goals of the program are to: (1) support the development of testing protocols and standards for cookstoves through ISO (International Organization for Standardization) TC (Technical Committee) 285: Clean Cookstoves and Clean Cooking Solutions, (2) support the development of international Regional Testing and Knowledge Centers (many sponsored by the Alliance) for scientifically evaluating and certifying cookstoves to international standards, and (3) provide an independent source of data to Alliance partners. This work supports EPA’s mission to protect human health and the environment. Household air pollution, mainly from solid-fuel cookstoves in the developing world, is estimated to cause approximately 4 million premature deaths per year, and emissions of black carbon and other pollutants from cookstoves aff

NATIONAL RISK MANAGEMENT RESEARCH LABORATORY - PROVIDING SOLUTIONS FOR A BETTER TOMORROW

EPA Science Inventory

As part of the U.S. Environmental Protection Agency's Office of Research and Development, the National Risk Management Research Laboratory (NRMRL) conducts research into ways to prevent and reduce pollution risks that threaten human health and the environment. The laboratory inve...

United States Air Force Summer Research Program -- 1993. Volume 13. Phillips Laboratory

DTIC Science & Technology

1993-12-01

Research Kirtland Air Force Base, Albuquerque, NM August 1993 14-1 My Summer Apprenticeship At Kirtland Air Force Base, Phillips Laboratory Andrea Garcia...AFOSR Summer Research Program Phillips Laboratory Sponsored By: Air Force Office of Scientific Research Kirtland Air Force Base, Albuquerque, NM... Phillips Laboratory Sponsored by: Air

United States Air Force Summer Research Program -- 1993. Volume 3. Phillips Laboratory

DTIC Science & Technology

1993-12-01

PHILLIPS LABORATORY KIRTLAND AIR FORCE BASE, NEW MEXICO SPONSORED BY: AIR FORCE OFFICE OF SCIENTIFIC RESEARCH ROLLING AIR FORCE BASE, WASHINGTON ,D.C...Report for. Summer Faculty Research Program at Phillips Laboratory Kirtland Air Force Base Sponsored by: Air Force Offlce of Scientific Research ...Prcgram Phillips Laboratory Kirtland

2014 Fermilab Laboratory Directed Research & Development Program Plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wester, W., editor

2016-05-26

Fermilab is executing Laboratory Directed Research and Development (LDRD) as outlined by order DOE O 413.2B in order to enhance and realize the mission of the laboratory in a manner that also supports the laboratory’s strategic objectives and the mission of the Department of Energy. LDRD funds enable scientific creativity, allow for exploration of “high risk, high payoff” research, and allow for the demonstration of new ideas, technical concepts, and devices. LDRD also has an objective of maintaining and enhancing the scientific and technical vitality of Fermilab.

Visiting Scholars Program | Frederick National Laboratory for Cancer Research

Cancer.gov

The Visiting Scholars Program (VSP) provides a unique opportunity for scientists to collaborate with the Frederick National Laboratory for Cancer Research (FNLCR), the only federal national laboratory in the United States devoted exclusively to b

Resolving Complex Research Data Management Issues in Biomedical Laboratories: Qualitative Study of an Industry-Academia Collaboration

PubMed Central

Myneni, Sahiti; Patel, Vimla L.; Bova, G. Steven; Wang, Jian; Ackerman, Christopher F.; Berlinicke, Cynthia A.; Chen, Steve H.; Lindvall, Mikael; Zack, Donald J.

2016-01-01

This paper describes a distributed collaborative effort between industry and academia to systematize data management in an academic biomedical laboratory. Heterogeneous and voluminous nature of research data created in biomedical laboratories make information management difficult and research unproductive. One such collaborative effort was evaluated over a period of four years using data collection methods including ethnographic observations, semi-structured interviews, web-based surveys, progress reports, conference call summaries, and face-to-face group discussions. Data were analyzed using qualitative methods of data analysis to 1) characterize specific problems faced by biomedical researchers with traditional information management practices, 2) identify intervention areas to introduce a new research information management system called Labmatrix, and finally to 3) evaluate and delineate important general collaboration (intervention) characteristics that can optimize outcomes of an implementation process in biomedical laboratories. Results emphasize the importance of end user perseverance, human-centric interoperability evaluation, and demonstration of return on investment of effort and time of laboratory members and industry personnel for success of implementation process. In addition, there is an intrinsic learning component associated with the implementation process of an information management system. Technology transfer experience in a complex environment such as the biomedical laboratory can be eased with use of information systems that support human and cognitive interoperability. Such informatics features can also contribute to successful collaboration and hopefully to scientific productivity. PMID:26652980

Kathleen Igo | Frederick National Laboratory for Cancer Research

Cancer.gov

Directorate: Clinical Research Program Department or lab: Clinical Monitoring Research Program (CMRP) How many years have you worked at the Frederick National Laboratory? I am in my 7th year of employment.

ORNLs Laboratory Directed Research and Development Program FY 2009 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2010-03-01

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2009. The associated FY 2009 ORNL LDRD Self-Assessment (ORNL/PPA-2010/2) provides financial data andmore » an internal evaluation of the program’s management process.« less

ORNLs Laboratory Directed Research and Development Program FY 2013 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2014-03-01

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the US Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2013. The associated FY 2013 ORNL LDRD Self-Assessment (ORNL/PPA-2014/2) provides financial datamore » and an internal evaluation of the program’s management process.« less

ORNLs Laboratory Directed Research and Development Program FY 2008 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2009-03-01

The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2008. The associated FY 2008 ORNL LDRD Self-Assessment (ORNL/PPA-2008/2) provides financial data and anmore » internal evaluation of the program’s management process.« less

ORNLs Laboratory Directed Research and Development Program FY 2012 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2013-03-01

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the US Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2012. The associated FY 2012 ORNL LDRD Self-Assessment (ORNL/PPA-2012/2) provides financial datamore » and an internal evaluation of the program’s management process.« less

Laboratory Directed Research and Development FY 2000 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Al-Ayat, R

This Annual Report provides an overview of the FY2000 Laboratory Directed Research and Development (LDRD) Program at Lawrence Livermore National Laboratory (LLNL) and presents a summary of the results achieved by each project during the year.

US Army Research Laboratory and University of Notre Dame Distributed Sensing: Software Overview

DTIC Science & Technology

2017-09-01

ARL-TN-0847 ● Sep 2017 US Army Research Laboratory US Army Research Laboratory and University of Notre Dame Distributed Sensing...Destroy this report when it is no longer needed. Do not return it to the originator. ARL-TN-0847 ● Sep 2017 US Army Research Laboratory...US Army Research Laboratory and University of Notre Dame Distributed Sensing: Software Overview by Neal Tesny Sensors and Electron Devices

Advances in Behavioral Laboratory Methods that Inform Tobacco Regulatory Science: A TCORS Working Group Special Issue

PubMed Central

Wright, M. Jerry; Valentine, Gerald

2017-01-01

Objective The 2009 Family Smoking Prevention and Tobacco Control Act (TCA) created unprecented enabling conditions for establishing national regulatory policy that reduces the burden of public health and societal problems associated with tobacco product use. The Center for Tobacco Products (CTP), created by the FDA to implement the TCA, developed a first-of-its-kind FDA/National Institutes of Health (NIH) collaborative program to fund Tobacco Centers of Regulatory Science (TCORS). Methods To assist the TCORS with addressing research priorites, working groups (WGs) comprised of FDA-CTP liasions and TCORS investigators were formed. Under the direction of the Center for Evaluation and Coordination of Trainin and Research (CECTR), the TCORS WGs seek to develop tangible work products in their respective areas of focus. Results The focus of the behavioral pharmacology WG evolved from publishing a narrow paper on behavioral methods in electronic cigarette research to a collection of papers on advances in behavioral laboratory methods that may inform tobacco regulatory science. Conclusion This Special Issue contains articles that address all of the CTP research priorities and demonstrates how advances in behavioral laboratory methods made by TCORS investigators can inform FDA efforst to regulate tobacco products. PMID:29152546

Summer Research Program (1992). Summer Faculty Research Program (SFRP) Reports. Volume 5A. Wright Laboratory

DTIC Science & Technology

1992-12-01

1992 6-~1 SOME RESULTS IN MACIIINE- LEARNING Mike Breen Assistant Professor Department of Mathematics Tennessee Technological Universitv Abstract The...Research Laboratory; Wilford Hall Medical Center 12 High School Apprenticeship Program Reports: Armstrong Laboratory 13 High School Apprenticeship ...Program Reports: Phillips Laboratory 14 High School Apprenticeship Program Reports: Rome Laboratory 15 High School Apprenticeship Program Reports

Laboratory-Directed Research and Development 2016 Summary Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pillai, Rekha Sukamar; Jacobson, Julie Ann

The Laboratory-Directed Research and Development (LDRD) Program at Idaho National Laboratory (INL) reports its status to the U.S. Department of Energy (DOE) by March of each year. The program operates under the authority of DOE Order 413.2C, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the laboratory director broad flexibility for program implementation. LDRD funds are obtained through a charge to all INL programs. This report includes summaries of all INL LDRD research activities supported during Fiscal Year (FY) 2016. INL is the lead laboratory for the DOE Office of Nuclearmore » Energy (DOE-NE). The INL mission is to discover, demonstrate, and secure innovative nuclear energy solutions, other clean energy options, and critical infrastructure with a vision to change the world’s energy future and secure our critical infrastructure. Operating since 1949, INL is the nation’s leading research, development, and demonstration center for nuclear energy, including nuclear nonproliferation and physical and cyber-based protection of energy systems and critical infrastructure, as well as integrated energy systems research, development, demonstration, and deployment. INL has been managed and operated by Battelle Energy Alliance, LLC (a wholly owned company of Battelle) for DOE since 2005. Battelle Energy Alliance, LLC, is a partnership between Battelle, BWX Technologies, Inc., AECOM, the Electric Power Research Institute, the National University Consortium (Massachusetts Institute of Technology, Ohio State University, North Carolina State University, University of New Mexico, and Oregon State University), and the Idaho university collaborators (i.e., University of Idaho, Idaho State University, and Boise State University). Since its creation, INL’s research and development (R&D) portfolio has broadened with targeted programs supporting national missions to advance nuclear

Enabling UAS Research at the NASA EAV Laboratory

NASA Technical Reports Server (NTRS)

Ippolito, Corey A.

2015-01-01

The Exploration Aerial Vehicles (EAV) Laboratory at NASA Ames Research Center leads research into intelligent autonomy and advanced control systems, bridging the gap between simulation and full-scale technology through flight test experimentation on unmanned sub-scale test vehicles.

The role of veterinary research laboratories in the provision of veterinary services.

PubMed

Verwoerd, D W

1998-08-01

Veterinary research laboratories play an essential role in the provision of veterinary services in most countries. These laboratories are the source of new knowledge, innovative ideas and improved technology for the surveillance, prevention and control of animal diseases. In addition, many laboratories provide diagnostic and other services. To ensure the optimal integration of various veterinary activities, administrators must understand the functions and constraints of research laboratories. Therefore, a brief discussion is presented of the following: organisational structures methods for developing research programmes outputs of research scientists and how these are measured the management of quality assurance funding of research. Optimal collaboration can only be attained by understanding the environment in which a research scientist functions and the motivational issues at stake.

Progress of applied superconductivity research at Materials Research Laboratories, ITRI (Taiwan)

NASA Technical Reports Server (NTRS)

Liu, R. S.; Wang, C. M.

1995-01-01

A status report based on the applied high temperature superconductivity (HTS) research at Materials Research Laboratories (MRL), Industrial Technology Research Institute (ITRI) is given. The aim is to develop fabrication technologies for the high-TC materials appropriate to the industrial application requirements. To date, the majorities of works have been undertaken in the areas of new materials, wires/tapes with long length, prototypes of magnets, large-area thin films, SQUID's and microwave applications.

Research Update: The USDA-ARS-Conservation and Production Research Laboratory, Bushland, Texas

USDA-ARS?s Scientific Manuscript database

This presentation/manuscript provide a brief summary of beef cattle feeding-related research conducted at the USDA-ARS-Conservation and Production Research Laboratory, Bushland, Texas, over the past four years. It summarizes data that has been published in scientific journals, in symposia and confer...

Report of the Field and Laboratory Utilization Study Group. Appendix

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1975-12-01

These appendices (ERDA organization and management, summary of other resources, and FLU study considerations/inputs) provide detailed and quantitative information in support of the findings and recommendations presented in the report of the field and laboratory utilization study group. (RWR)

Revealing all: misleading self-disclosure rates in laboratory-based online research.

PubMed

Callaghan, Diana E; Graff, Martin G; Davies, Joanne

2013-09-01

Laboratory-based experiments in online self-disclosure research may be inadvertently compromising the accuracy of research findings by influencing some of the factors known to affect self-disclosure behavior. Disclosure-orientated interviews conducted with 42 participants in the laboratory and in nonlaboratory settings revealed significantly greater breadth of self-disclosure in laboratory interviews, with message length and intimacy of content also strongly related. These findings suggest that a contrived online setting with a researcher presence may stimulate motivation for greater self-disclosure than would occur naturally in an online environment of an individual's choice. The implications of these findings are that researchers should consider the importance of experimental context and motivation in self-disclosure research.

Aerial View of NACA's Lewis Flight Propulsion Research Laboratory

NASA Image and Video Library

1946-05-21

The National Advisory Committee for Aeronautics (NACA) Lewis Flight Propulsion Laboratory in Cleveland, Ohio as seen from the west in May 1946. The Cleveland Municipal Airport is located directly behind. The laboratory was built in the early 1940s to resolve problems associated with aircraft engines. The initial campus contained seven principal buildings: the Engine Research Building, hangar, Fuels and Lubricants Building, Administration Building, Engine Propeller Research Building, Altitude Wind Tunnel, and Icing Research Tunnel. These facilities and their associated support structures were located within an area occupying approximately one-third of the NACA’s property. After World War II ended, the NACA began adding new facilities to address different problems associated with the newer, more powerful engines and high speed flight. Between 1946 and 1955, four new world-class test facilities were built: the 8- by 6-Foot Supersonic Wind Tunnel, the Propulsion Systems Laboratory, the Rocket Engine Test Facility, and the 10- by 10-Foot Supersonic Wind Tunnel. These large facilities occupied the remainder of the NACA’s semicircular property. The Lewis laboratory expanded again in the late 1950s and early 1960s as the space program commenced. Lewis purchased additional land in areas adjacent to the original laboratory and acquired a large 9000-acre site located 60 miles to the west in Sandusky, Ohio. The new site became known as Plum Brook Station.

Integrating Interdisciplinary Research-Based Experiences in Biotechnology Laboratories

ERIC Educational Resources Information Center

Iyer, Rupa S.; Wales, Melinda E.

2012-01-01

The increasingly interdisciplinary nature of today's scientific research is leading to the transformation of undergraduate education. In addressing these needs, the University of Houston's College of Technology has developed a new interdisciplinary research-based biotechnology laboratory curriculum. Using the pesticide degrading bacterium,…

An overview of Quality Management System implementation in a research laboratory

NASA Astrophysics Data System (ADS)

Molinéro-Demilly, Valérie; Charki, Abdérafi; Jeoffrion, Christine; Lyonnet, Barbara; O'Brien, Steve; Martin, Luc

2018-02-01

The aim of this paper is to show the advantages of implementing a Quality Management System (QMS) in a research laboratory in order to improve the management of risks specific to research programmes and to increase the reliability of results. This paper also presents experience gained from feedback following the implementation of the Quality process in a research laboratory at INRA, the French National Institute for Agronomic Research and details the various challenges encountered and solutions proposed to help achieve smoother adoption of a QMS process. The 7Ms (Management, Measurement, Manpower, Methods, Materials, Machinery, Mother-nature) methodology based on the Ishikawa `Fishbone' diagram is used to show the effectiveness of the actions considered by a QMS, which involve both the organization and the activities of the laboratory. Practical examples illustrate the benefits and improvements observed in the laboratory.

Resolving complex research data management issues in biomedical laboratories: Qualitative study of an industry-academia collaboration.

PubMed

Myneni, Sahiti; Patel, Vimla L; Bova, G Steven; Wang, Jian; Ackerman, Christopher F; Berlinicke, Cynthia A; Chen, Steve H; Lindvall, Mikael; Zack, Donald J

2016-04-01

This paper describes a distributed collaborative effort between industry and academia to systematize data management in an academic biomedical laboratory. Heterogeneous and voluminous nature of research data created in biomedical laboratories make information management difficult and research unproductive. One such collaborative effort was evaluated over a period of four years using data collection methods including ethnographic observations, semi-structured interviews, web-based surveys, progress reports, conference call summaries, and face-to-face group discussions. Data were analyzed using qualitative methods of data analysis to (1) characterize specific problems faced by biomedical researchers with traditional information management practices, (2) identify intervention areas to introduce a new research information management system called Labmatrix, and finally to (3) evaluate and delineate important general collaboration (intervention) characteristics that can optimize outcomes of an implementation process in biomedical laboratories. Results emphasize the importance of end user perseverance, human-centric interoperability evaluation, and demonstration of return on investment of effort and time of laboratory members and industry personnel for success of implementation process. In addition, there is an intrinsic learning component associated with the implementation process of an information management system. Technology transfer experience in a complex environment such as the biomedical laboratory can be eased with use of information systems that support human and cognitive interoperability. Such informatics features can also contribute to successful collaboration and hopefully to scientific productivity. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Location | Frederick National Laboratory for Cancer Research

Cancer.gov

The Frederick National Laboratory for Cancer Research campus is located 50 miles northwest of Washington, D.C., and 50 miles west of Baltimore, Maryland, in Frederick, Maryland. Satellite locations include leased and government facilities extending s

Outcomes of a Research-Driven Laboratory and Literature Course Designed to Enhance Undergraduate Contributions to Original Research

ERIC Educational Resources Information Center

Rasche, Madeline E.

2004-01-01

This work describes outcomes of a research-driven advanced microbiology laboratory and literature research course intended to enhance undergraduate preparation for and contributions to original research. The laboratory section was designed to teach fundamental biochemistry and molecular biology techniques in the context of an original research…

NACA Pilots at the Aircraft Engine Research Laboratory

NASA Image and Video Library

1945-07-21

The Aircraft Engine Research Laboratory’s pilot corps during the final days of World War II: from left to right, Joseph Vensel, Howard Lilly, William Swann, and Joseph Walker. William “Eb” Gough joined the group months after this photograph. These men were responsible for flying the various National Advisory Committee for Aeronautics (NACA) aircraft to test new engine modifications, study ice buildup, and determine fuel performance. Vensel, a veteran pilot from Langley, was the Chief of Flight Operations and a voice of reason at the laboratory. In April 1947 Vensel was transferred to lead the new Muroc Flight Tests Unit in California until 1966. Lilly was a young pilot with recent Navy experience. Lilly also flew in the 1946 National Air Races. He followed Vensel to Muroc in July 1947 where he became the first NACA pilot to penetrate the sound barrier. On May 3, 1948, Lilly became the first NACA pilot to die in the line of duty. Swann was a young civilian pilot when he joined the NACA. He spent his entire career at the Cleveland laboratory, and led the flight operations group from the early 1960s until 1979. Two World War II veterans joined the crew after the war. Walker was a 24-year-old P–38 reconnaissance pilot. He joined the NACA as a physicist in early 1945 but soon worked his way into the cadre of pilots. Walker later gained fame as an X-plane pilot at Muroc and was killed in a June 1966 fatal crash. Gough survived being shot down twice during the war and was decorated for flying rescue missions in occupied areas.

NRMRL SCIENCE PUBLICATIONS (NATIONAL RISK MANAGEMENT RESEARCH LABORATORY, EPA, CINCINNATI, OH)

EPA Science Inventory

The National Risk Management Research Laboratory (NRMRL)is the U.S.EPA's center for investigating technological and management approaches for preventing and reducing risks from pollution that threaten human health and the environment. The focus of the Laboratory's research progra...

NASA DC-8 airborne research laboratory

NASA Technical Reports Server (NTRS)

Degreef, Leo H.

1991-01-01

Since the summer of 1987, NASA Ames Research Center has been operating a DC-8 equipped with CFM 56 engines as a flying research laboratory. In this relatively short time, the DC-8, with its tremendous capabilities, has made significant contributions to numerous scientific fields. Capable of staying aloft for over 12 hours, the DC-8 has flown directly over both the North and South Poles, gathering data relating to the ozone hole. Operating from a few thousand feet to over 40,000 feet above sea level the interchangeable payload capability of the DC-8 has made it a versatile scientific tool. The DC-8 also plays a vital role in the development of new satellite-borne sensors as very often those sensors are test-flown on the DC-8 before they are launched into space. The tremendous range and instrument carrying capability make the DC-8 an ideal flying laboratory. A few of the programs the DC-8 has participated in as well as a sampling of the instruments carried are outlined.

Laboratory Directed Research and Development Program FY2016 Annual Summary of Completed Projects

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

ORNL FY 2016 Annual Summary of Laboratory Directed Research and Development Program (LDRD) Completed Projects. The Laboratory Directed Research and Development (LDRD) program at ORNL operates under the authority of DOE Order 413.2C, “Laboratory Directed Research and Development” (October 22, 2015), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. The LDRD program funds are obtained through a charge to all Laboratory programs. ORNL reports its status to DOE in March of each year.

Senior Laboratory Animal Technician | Center for Cancer Research

Cancer.gov

PROGRAM DESCRIPTION The Laboratory Animal Sciences Program (LASP) provides exceptional quality animal care and technical support services for animal research performed at the National Cancer Institute at the Frederick National Laboratory for Cancer Research. LASP executes this mission by providing a broad spectrum of state-of-the-art technologies and services that are focused on the design, generation, characterization and application of genetically engineered and biological animal models of human disease, which are aimed at the development of targeted diagnostics and therapies. LASP contributes to advancing human health, developing new treatments, and improving existing treatments for cancer and other diseases while ensuring safe and humane treatment of animals. KEY ROLES/RESPONSIBILITIES The Senior Laboratory Animal Technician will be responsible for: Daily tasks associated with the care, breeding and treatment of research animals for experimental purposes Management of rodent breeding colonies consisting of multiple, genetically complex strains and associated record keeping and database management Colony management procedures including: tail clipping, animal identification, weaning Data entry consistent with complex colony management Collection of routine diagnostic samples Coordinating shipment of live animals and specimens Performing rodent experimental procedures including basic necropsy and blood collection Observation and recording of physical signs of animal health Knowledge of safe working practices using chemical carcinogen and biological hazards Work schedule may include weekend and holiday hours This position is in support of the Center for Cancer Research (CCR).

DESALINATION AND WATER TREATMENT RESEARCH AT SANDIA NATIONAL LABORATORIES.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rigali, Mark J.; Miller, James E.; Altman, Susan J.

Water is the backbone of our economy - safe and adequate supplies of water are vital for agriculture, industry, recreation, and human consumption. While our supply of water today is largely safe and adequate, we as a nation face increasing water supply challenges in the form of extended droughts, demand growth due to population increase, more stringent health-based regulation, and competing demands from a variety of users. To meet these challenges in the coming decades, water treatment technologies, including desalination, will contribute substantially to ensuring a safe, sustainable, affordable, and adequate water supply for the United States. This overview documentsmore » Sandia National Laboratories' (SNL, or Sandia) Water Treatment Program which focused on the development and demonstration of advanced water purification technologies as part of the larger Sandia Water Initiative. Projects under the Water Treatment Program include: (1) the development of desalination research roadmaps (2) our efforts to accelerate the commercialization of new desalination and water treatment technologies (known as the 'Jump-Start Program),' (3) long range (high risk, early stage) desalination research (known as the 'Long Range Research Program'), (4) treatment research projects under the Joint Water Reuse & Desalination Task Force, (5) the Arsenic Water Technology Partnership Program, (6) water treatment projects funded under the New Mexico Small Business Administration, (7) water treatment projects for the National Energy Technology Laboratory (NETL) and the National Renewable Energy Laboratory (NREL), (8) Sandia- developed contaminant-selective treatment technologies, and finally (9) current Laboratory Directed Research and Development (LDRD) funded desalination projects.« less

Group selections among laboratory populations of Tribolium.

PubMed

Wade, M J

1976-12-01

Selection at the population level or group selection is defined as genetic change that is brought about or maintained by the differential extinction and/or proliferation of populations. Group selection for both increased and decreased adult population size was carried out among laboratory populations of Tribolium castaneum at 37-day intervals. The effect of individual selection within populations on adult population size was evaluated in an additional control series of populations. The response in the group selection treatments occurred rapidly, within three or four generations, and was large in magnitude, at times differing from the controls by over 200%. This response to selection at the populational level occurred despite strong individual selection which caused a decline in the mean size of the control populations from over 200 adults to near 50 adults in nine 37-day intervals. "Assay" experiments indicated that selective changes in fecundity, developmental time, body weight, and cannibalism rates were responsible in part for the observed treatment differences in adult population size. These findings have implications in terms of speciation in organisms whose range is composed of many partially isolated local populations.

Laboratory directed research and development FY98 annual report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Al-Ayat, R; Holzrichter, J

1999-05-01

In 1984, Congress and the Department of Energy (DOE) established the Laboratory Directed Research and Development (LDRD) Program to enable the director of a national laboratory to foster and expedite innovative research and development (R and D) in mission areas. The Lawrence Livermore National Laboratory (LLNL) continually examines these mission areas through strategic planning and shapes the LDRD Program to meet its long-term vision. The goal of the LDRD Program is to spur development of new scientific and technical capabilities that enable LLNL to respond to the challenges within its evolving mission areas. In addition, the LDRD Program provides LLNLmore » with the flexibility to nurture and enrich essential scientific and technical competencies and enables the Laboratory to attract the most qualified scientists and engineers. The FY98 LDRD portfolio described in this annual report has been carefully structured to continue the tradition of vigorously supporting DOE and LLNL strategic vision and evolving mission areas. The projects selected for LDRD funding undergo stringent review and selection processes, which emphasize strategic relevance and require technical peer reviews of proposals by external and internal experts. These FY98 projects emphasize the Laboratory's national security needs: stewardship of the U.S. nuclear weapons stockpile, responsibility for the counter- and nonproliferation of weapons of mass destruction, development of high-performance computing, and support of DOE environmental research and waste management programs.« less

Open- and closed-formula laboratory animal diets and their importance to research.

PubMed

Barnard, Dennis E; Lewis, Sherry M; Teter, Beverly B; Thigpen, Julius E

2009-11-01

Almost 40 y ago the scientific community was taking actions to control environmental factors that contribute to variation in the responses of laboratory animals to scientific manipulation. Laboratory animal diet was recognized as an important variable. During the 1970s, the American Institute of Nutrition, National Academy of Science, Institute of Laboratory Animal Resources, and Laboratory Animals Centre Diets Advisory Committee supported the use of 'standard reference diets' in biomedical research as a means to improve the ability to replicate research. As a result the AIN76 purified diet was formulated. During this same time, the laboratory animal nutritionist at the NIH was formulating open-formula, natural-ingredient diets to meet the need for standardized laboratory animal diets. Since the development of open-formula diets, fixed-formula and constant-nutrient-concentration closed-formula laboratory animal natural ingredient diets have been introduced to help reduce the potential variation diet can cause in research.

Open- and Closed-Formula Laboratory Animal Diets and Their Importance to Research

PubMed Central

Barnard, Dennis E; Lewis, Sherry M; Teter, Beverly B; Thigpen, Julius E

2009-01-01

Almost 40 y ago the scientific community was taking actions to control environmental factors that contribute to variation in the responses of laboratory animals to scientific manipulation. Laboratory animal diet was recognized as an important variable. During the 1970s, the American Institute of Nutrition, National Academy of Science, Institute of Laboratory Animal Resources, and Laboratory Animals Centre Diets Advisory Committee supported the use of ‘standard reference diets’ in biomedical research as a means to improve the ability to replicate research. As a result the AIN76 purified diet was formulated. During this same time, the laboratory animal nutritionist at the NIH was formulating open-formula, natural-ingredient diets to meet the need for standardized laboratory animal diets. Since the development of open-formula diets, fixed-formula and constant-nutrient–concentration closed-formula laboratory animal natural ingredient diets have been introduced to help reduce the potential variation diet can cause in research. PMID:19930817

M2 .50-cal. Multishot Capabilities at the US Army Research Laboratory

DTIC Science & Technology

2015-09-01

a platform was designed to simulate the 2-round burst of the M2 .50-caliber Browning machine gun (BMG). The 2-round-burst cyclic rate was achieved...ARL-TN-0694 ● SEP 2015 US Army Research Laboratory M2 .50-cal. Multishot Capabilities at the US Army Research Laboratory by...longer needed. Do not return it to the originator. ARL-TN-0694 ● SEP 2015 US Army Research Laboratory M2 .50-cal. Multishot

Research Notes. OERI's Regional Laboratory Technology Efforts.

ERIC Educational Resources Information Center

Garnette, Cheryl P., Ed.; Withrow, Frank B., Ed.

1989-01-01

Examines various educational technology projects that regional laboratories supported by the Office of Educational Research and Improvement (OERI) are undertaking. Highlights include innovative uses of instructional technology; tele-teaching using interactive audio conferencing; making informed decisions about technology; national teleconferences…

Accessibility | Frederick National Laboratory for Cancer Research

Cancer.gov

The Frederick National Laboratory for Cancer Research campus is making every effort to ensure that the information available on our website is accessible to all. If you use special adaptive equipment to access the web and encounter problems when usin

Sandia National Laboratories: Cooperative Research and Development

Science.gov Websites

; Technology Defense Systems & Assessments About Defense Systems & Assessments Program Areas Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

FRESHWATER FINDINGS, 1979-1982: RESEARCH PUBLICATIONS OF THE ENVIRONMENTAL RESEARCH LABORATORY, DULUTH, MINNESOTA

EPA Science Inventory

This report contains citations of publications for the years 1979-1982 on research conducted or supported by the Environmental Research Laboratory-Duluth. All published material has been organized into two major categories: (1) Journal Articles, Book Chapters, Proceedings, etc., ...

FY2007 Laboratory Directed Research and Development Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Craig, W W; Sketchley, J A; Kotta, P R

The Laboratory Directed Research and Development (LDRD) annual report for fiscal year 2007 (FY07) provides a summary of LDRD-funded projects for the fiscal year and consists of two parts: An introduction to the LDRD Program, the LDRD portfolio-management process, program statistics for the year, and highlights of accomplishments for the year. A summary of each project, submitted by the principal investigator. Project summaries include the scope, motivation, goals, relevance to Department of Energy (DOE)/National Nuclear Security Administration (NNSA) and Lawrence Livermore National Laboratory (LLNL) mission areas, the technical progress achieved in FY07, and a list of publications that resulted frommore » the research in FY07. Summaries are organized in sections by research category (in alphabetical order). Within each research category, the projects are listed in order of their LDRD project category: Strategic Initiative (SI), Exploratory Research (ER), Laboratory-Wide Competition (LW), and Feasibility Study (FS). Within each project category, the individual project summaries appear in order of their project tracking code, a unique identifier that consists of three elements. The first is the fiscal year the project began, the second represents the project category, and the third identifies the serial number of the proposal for that fiscal year.« less

Laboratory directed research and development fy1999 annual report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Al-Ayat, R A

2000-04-11

The Lawrence Livermore National Laboratory (LLNL) was founded in 1952 and has been managed since its inception by the University of California (UC) for the U.S. Department of Energy (DOE). Because of this long association with UC, the Laboratory has been able to recruit a world-class workforce, establish an atmosphere of intellectual freedom and innovation, and achieve recognition in relevant fields of knowledge as a scientific and technological leader. This environment and reputation are essential for sustained scientific and technical excellence. As a DOE national laboratory with about 7,000 employees, LLNL has an essential and compelling primary mission to ensuremore » that the nation's nuclear weapons remain safe, secure, and reliable and to prevent the spread and use of nuclear weapons worldwide. The Laboratory receives funding from the DOE Assistant Secretary for Defense Programs, whose focus is stewardship of our nuclear weapons stockpile. Funding is also provided by the Deputy Administrator for Defense Nuclear Nonproliferation, many Department of Defense sponsors, other federal agencies, and the private sector. As a multidisciplinary laboratory, LLNL has applied its considerable skills in high-performance computing, advanced engineering, and the management of large research and development projects to become the science and technology leader in those areas of its mission responsibility. The Laboratory Directed Research and Development (LDRD) Program was authorized by the U.S. Congress in 1984. The Program allows the Director of each DOE laboratory to fund advanced, creative, and innovative research and development (R&D) activities that will ensure scientific and technical vitality in the continually evolving mission areas at DOE and the Laboratory. In addition, the LDRD Program provides LLNL with the flexibility to nurture and enrich essential scientific and technical competencies, which attract the most qualified scientists and engineers. The LDRD

Model of the NACA's Aircraft Engine Research Laboratory during its Construction

NASA Image and Video Library

1942-08-21

Zella Morewitz poses with a model of the National Advisory Committee for Aeronautics (NACA) Aircraft Engine Research Laboratory, currently the NASA Glenn Research Center. The model was displayed in the Administration Building during the construction of the laboratory in the early 1940s. Detailed models of the individual test facilities were also fabricated and displayed in the facilities. The laboratory was built on a wedge of land between the Cleveland Municipal Airport on the far side and the deep curving valley etched by the Rocky River on the near end. Roughly only a third of the laboratory's semicircle footprint was initially utilized. Additional facilities were added to the remaining areas in the years after World War II. In the late 1950s the site was supplemented by the acquisition of additional adjacent land. Morewitz joined the NACA in 1935 as a secretary in the main office at the Langley Memorial Aeronautical Laboratory. In September 1940 she took on the task of setting up and guiding an office dedicated to the design of the NACA’s new engine research laboratory. Morewitz and the others in the design office transferred to Cleveland in December 1941 to expedite the construction. Morewitz served as Manager Ray Sharp’s secretary for six years and was a popular figure at the new laboratory. In December 1947 Morewitz announced her engagement to Langley researcher Sidney Batterson and moved back to Virginia.

A 50-year research journey. From laboratory to clinic.

PubMed

Ross, John

2009-01-01

Prior important research is not always cited, exemplified by Oswald Avery's pioneering discovery that DNA is the genetic transforming factor; it was not cited by Watson and Crick 10 years later. My first laboratory research (National Institutes of Health 1950s) resulted in the clinical development of transseptal left heart catheterization. Laboratory studies on cardiac muscle mechanics in normal and failing hearts led to the concept of afterload mismatch with limited preload reserve. At the University of California, San Diego in La Jolla (1968) laboratory experiments on coronary artery reperfusion after sustained coronary occlusion showed salvage of myocardial tissue, a potential treatment for acute myocardial infarction proven in clinical trials of thrombolysis 14 years later. Among 60 trainees who worked with me in La Jolla, one-third were Japanese and some of their important laboratory experiments are briefly recounted, beginning with Sasayama, Tomoike and Shirato in the 1970 s. Recently, we developed a method for cardiac gene transfer, and subsequently we showed that gene therapy for the defect in cardiomyopathic hamsters halted the progression of advanced disease. Cardiovascular research and medicine are producing continuing advances in technologies for gene transfer and embryonic stem cell transplantation, targeting of small molecules, and tissue and organ engineering.

Air conditioning a vaccine laboratory. [Connaught Medical Research Laboratory, Toronto, Canada

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ross J.

1976-05-01

In 1974, the new Bacterial Vaccine Building of Connaught Medical Research Laboratories, Toronto, Canada, was opened to produce such vaccines as pertussis, typhoid, paratyphoids, and cholera and such toxoids as staphylococcus, diphtheria, and tetanus. It also produces other medicinal products. The layout of the complex and the air conditioning system necessary in all zones are described and schematically shown. (MCW)

Research Opportunities at Storm Peak Laboratory

NASA Astrophysics Data System (ADS)

Hallar, A. G.; McCubbin, I. B.

2006-12-01

The Desert Research Institute (DRI) operates a high elevation facility, Storm Peak Laboratory (SPL), located on the west summit of Mt. Werner in the Park Range near Steamboat Springs, Colorado at an elevation of 3210 m MSL (Borys and Wetzel, 1997). SPL provides an ideal location for long-term research on the interactions of atmospheric aerosol and gas- phase chemistry with cloud and natural radiation environments. The ridge-top location produces almost daily transition from free tropospheric to boundary layer air which occurs near midday in both summer and winter seasons. Long-term observations at SPL document the role of orographically induced mixing and convection on vertical pollutant transport and dispersion. During winter, SPL is above cloud base 25% of the time, providing a unique capability for studying aerosol-cloud interactions (Borys and Wetzel, 1997). A comprehensive set of continuous aerosol measurements was initiated at SPL in 2002. SPL includes an office-type laboratory room for computer and instrumentation setup with outside air ports and cable access to the roof deck, a cold room for precipitation and cloud rime ice sample handling and ice crystal microphotography, a 150 m2 roof deck area for outside sampling equipment, a full kitchen and two bunk rooms with sleeping space for nine persons. The laboratory is currently well equipped for aerosol and cloud measurements. Particles are sampled from an insulated, 15 cm diameter manifold within approximately 1 m of its horizontal entry point through an outside wall. The 4 m high vertical section outside the building is capped with an inverted can to exclude large particles.

Preparing chimpanzees for laboratory research.

PubMed

Bloomsmith, Mollie A; Schapiro, Steven J; Strobert, Elizabeth A

2006-01-01

The chimpanzee is the only representative of the Great Apes that is extensively involved in biomedical research in primate laboratories. These apes are used as animal models in a variety of studies, including research on infectious disease, parasitic disease, pharmacokinetic studies, neuroscience, cognition, and behavior. Chimpanzees used in biomedical research in the United States reside largely in six specialized research and holding facilities, and most of the research with them is conducted at these sites. Given the relatively small population of chimpanzees and its importance to biomedical research, it is imperative that we carefully manage the care, production, and use of these animals in biomedical research studies. Selection criteria and preparation techniques are reviewed in this article in an effort to begin a discussion on best practices for choosing and handling chimpanzees participating in biomedical research. The use of routine health assessment information is described for subject selection, as are behavioral issues to be considered. Due to the relatively small number of chimpanzees available, issues related to experimental design and multiple uses of chimpanzees are discussed. Practices related to the transportation and acclimation of chimpanzees are described. Finally, behavioral conditioning procedures are discussed, including habituation, desensitization, and positive reinforcement training that have been applied to reduce animal distress and improve the quality of the science being conducted with chimpanzee subjects.

Laboratory Animal Management Assistant (LAMA): a LIMS for active research colonies.

PubMed

Milisavljevic, Marko; Hearty, Taryn; Wong, Tony Y T; Portales-Casamar, Elodie; Simpson, Elizabeth M; Wasserman, Wyeth W

2010-06-01

Laboratory Animal Management Assistant (LAMA) is an internet-based system for tracking large laboratory mouse colonies. It has a user-friendly interface with powerful search capabilities that ease day-to-day tasks such as tracking breeding cages and weaning litters. LAMA was originally developed to manage hundreds of new mouse strains generated by a large functional genomics program, the Pleiades Promoter Project ( http://www.pleiades.org ). The software system has proven to be highly flexible, suitable for diverse management approaches to mouse colonies. It allows custom tagging and grouping of animals, simplifying project-specific handling and access to data. Finally, LAMA was developed in close collaboration with mouse technicians to ease the transition from paper- or Excel-based management systems to computerized tracking, allowing data export in a popular spreadsheet format and automatic printing of cage cards. LAMA is an open-access software tool, freely available to the research community at http://launchpad.net/mousedb .

A laboratory medicine residency training program that includes clinical consultation and research.

PubMed

Spitzer, E D; Pierce, G F; McDonald, J M

1990-04-01

We describe a laboratory medicine residency training program that includes ongoing interaction with both clinical laboratories and clinical services as well as significant research experience. Laboratory medicine residents serve as on-call consultants in the interpretation of test results, design of testing strategies, and assurance of test quality. The consultative on-call beeper system was evaluated and is presented as an effective method of clinical pathology training that is well accepted by the clinical staff. The research component of the residency program is also described. Together, these components provide training in real-time clinical problem solving and prepare residents for the changing technological environment of the clinical laboratory. At the completion of the residency, the majority of the residents are qualified laboratory subspecialists and are also capable of running an independent research program.

Mobile robotics research at Sandia National Laboratories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Morse, W.D.

Sandia is a National Security Laboratory providing scientific and engineering solutions to meet national needs for both government and industry. As part of this mission, the Intelligent Systems and Robotics Center conducts research and development in robotics and intelligent machine technologies. An overview of Sandia`s mobile robotics research is provided. Recent achievements and future directions in the areas of coordinated mobile manipulation, small smart machines, world modeling, and special application robots are presented.

Regional Educational Laboratory Researcher-Practitioner Partnerships: Documenting the Research Alliance Experience. REL 2018-291

ERIC Educational Resources Information Center

Scher, Lauren; McCowan, Ronald; Castaldo-Walsh, Cynthia

2018-01-01

This report provides a detailed account of the Regional Educational Laboratory (REL) Program's experience establishing and supporting research-practice partnerships (called "research alliances") during its 2012-17 contract cycle. The report adds to the growing literature base on researcher-practitioner partnerships by sharing how the…

Redefining Authentic Research Experiences in Introductory Biology Laboratories and Barriers to Their Implementation

PubMed Central

Spell, Rachelle M.; Guinan, Judith A.; Miller, Kristen R.; Beck, Christopher W.

2014-01-01

Incorporating authentic research experiences in introductory biology laboratory classes would greatly expand the number of students exposed to the excitement of discovery and the rigor of the scientific process. However, the essential components of an authentic research experience and the barriers to their implementation in laboratory classes are poorly defined. To guide future reform efforts in this area, we conducted a national survey of biology faculty members to determine 1) their definitions of authentic research experiences in laboratory classes, 2) the extent of authentic research experiences currently experienced in their laboratory classes, and 3) the barriers that prevent incorporation of authentic research experiences into these classes. Strikingly, the definitions of authentic research experiences differ among faculty members and tend to emphasize either the scientific process or the discovery of previously unknown data. The low level of authentic research experiences in introductory biology labs suggests that more development and support is needed to increase undergraduate exposure to research experiences. Faculty members did not cite several barriers commonly assumed to impair pedagogical reform; however, their responses suggest that expanded support for development of research experiences in laboratory classes could address the most common barrier. PMID:24591509

Redefining authentic research experiences in introductory biology laboratories and barriers to their implementation.

PubMed

Spell, Rachelle M; Guinan, Judith A; Miller, Kristen R; Beck, Christopher W

2014-01-01

Incorporating authentic research experiences in introductory biology laboratory classes would greatly expand the number of students exposed to the excitement of discovery and the rigor of the scientific process. However, the essential components of an authentic research experience and the barriers to their implementation in laboratory classes are poorly defined. To guide future reform efforts in this area, we conducted a national survey of biology faculty members to determine 1) their definitions of authentic research experiences in laboratory classes, 2) the extent of authentic research experiences currently experienced in their laboratory classes, and 3) the barriers that prevent incorporation of authentic research experiences into these classes. Strikingly, the definitions of authentic research experiences differ among faculty members and tend to emphasize either the scientific process or the discovery of previously unknown data. The low level of authentic research experiences in introductory biology labs suggests that more development and support is needed to increase undergraduate exposure to research experiences. Faculty members did not cite several barriers commonly assumed to impair pedagogical reform; however, their responses suggest that expanded support for development of research experiences in laboratory classes could address the most common barrier.

The taming of the prairie: A century of agricultural research at the Northern Great Plains Research Laboratory

USDA-ARS?s Scientific Manuscript database

Nearly a century after Congress authorized the Northern Great Plains Research Laboratory, it had approximately 35 employees and an annual budget of 3.4 million dollars. The long history of research accomplishments from the Laboratory have been well accepted by the agricultural community and have ide...

Comparison of microbiological diagnosis of urinary tract infection in young children by routine health service laboratories and a research laboratory: Diagnostic cohort study.

PubMed

Birnie, Kate; Hay, Alastair D; Wootton, Mandy; Howe, Robin; MacGowan, Alasdair; Whiting, Penny; Lawton, Michael; Delaney, Brendan; Downing, Harriet; Dudley, Jan; Hollingworth, William; Lisles, Catherine; Little, Paul; O'Brien, Kathryn; Pickles, Timothy; Rumsby, Kate; Thomas-Jones, Emma; Van der Voort, Judith; Waldron, Cherry-Ann; Harman, Kim; Hood, Kerenza; Butler, Christopher C; Sterne, Jonathan A C

2017-01-01

To compare the validity of diagnosis of urinary tract infection (UTI) through urine culture between samples processed in routine health service laboratories and those processed in a research laboratory. We conducted a prospective diagnostic cohort study in 4808 acutely ill children aged <5 years attending UK primary health care. UTI, defined as pure/predominant growth ≥105 CFU/mL of a uropathogen (the reference standard), was diagnosed at routine health service laboratories and a central research laboratory by culture of urine samples. We calculated areas under the receiver-operator curve (AUC) for UTI predicted by pre-specified symptoms, signs and dipstick test results (the "index test"), separately according to whether samples were obtained by clean catch or nappy (diaper) pads. 251 (5.2%) and 88 (1.8%) children were classified as UTI positive by health service and research laboratories respectively. Agreement between laboratories was moderate (kappa = 0.36; 95% confidence interval [CI] 0.29, 0.43), and better for clean catch (0.54; 0.45, 0.63) than nappy pad samples (0.20; 0.12, 0.28). In clean catch samples, the AUC was lower for health service laboratories (AUC = 0.75; 95% CI 0.69, 0.80) than the research laboratory (0.86; 0.79, 0.92). Values of AUC were lower in nappy pad samples (0.65 [0.61, 0.70] and 0.79 [0.70, 0.88] for health service and research laboratory positivity, respectively) than clean catch samples. The agreement of microbiological diagnosis of UTI comparing routine health service laboratories with a research laboratory was moderate for clean catch samples and poor for nappy pad samples and reliability is lower for nappy pad than for clean catch samples. Positive results from the research laboratory appear more likely to reflect real UTIs than those from routine health service laboratories, many of which (particularly from nappy pad samples) could be due to contamination. Health service laboratories should consider adopting procedures used in

Comparison of microbiological diagnosis of urinary tract infection in young children by routine health service laboratories and a research laboratory: Diagnostic cohort study

PubMed Central

Birnie, Kate; Hay, Alastair D.; Wootton, Mandy; Howe, Robin; MacGowan, Alasdair; Whiting, Penny; Lawton, Michael; Delaney, Brendan; Downing, Harriet; Dudley, Jan; Hollingworth, William; Lisles, Catherine; Little, Paul; O’Brien, Kathryn; Pickles, Timothy; Rumsby, Kate; Thomas-Jones, Emma; Van der Voort, Judith; Waldron, Cherry-Ann; Harman, Kim; Hood, Kerenza; Butler, Christopher C.; Sterne, Jonathan A. C.

2017-01-01

Objectives To compare the validity of diagnosis of urinary tract infection (UTI) through urine culture between samples processed in routine health service laboratories and those processed in a research laboratory. Population and methods We conducted a prospective diagnostic cohort study in 4808 acutely ill children aged <5 years attending UK primary health care. UTI, defined as pure/predominant growth ≥105 CFU/mL of a uropathogen (the reference standard), was diagnosed at routine health service laboratories and a central research laboratory by culture of urine samples. We calculated areas under the receiver-operator curve (AUC) for UTI predicted by pre-specified symptoms, signs and dipstick test results (the “index test”), separately according to whether samples were obtained by clean catch or nappy (diaper) pads. Results 251 (5.2%) and 88 (1.8%) children were classified as UTI positive by health service and research laboratories respectively. Agreement between laboratories was moderate (kappa = 0.36; 95% confidence interval [CI] 0.29, 0.43), and better for clean catch (0.54; 0.45, 0.63) than nappy pad samples (0.20; 0.12, 0.28). In clean catch samples, the AUC was lower for health service laboratories (AUC = 0.75; 95% CI 0.69, 0.80) than the research laboratory (0.86; 0.79, 0.92). Values of AUC were lower in nappy pad samples (0.65 [0.61, 0.70] and 0.79 [0.70, 0.88] for health service and research laboratory positivity, respectively) than clean catch samples. Conclusions The agreement of microbiological diagnosis of UTI comparing routine health service laboratories with a research laboratory was moderate for clean catch samples and poor for nappy pad samples and reliability is lower for nappy pad than for clean catch samples. Positive results from the research laboratory appear more likely to reflect real UTIs than those from routine health service laboratories, many of which (particularly from nappy pad samples) could be due to contamination. Health service

Groundbreaking for the NACA’s Aircraft Engine Research Laboratory

NASA Image and Video Library

1941-01-21

Local politicians and National Advisory Committee for Aeronautics (NACA) officials were on hand for the January 23, 1941 groundbreaking for the NACA’s Aircraft Engine Research Laboratory (AERL). The NACA was established in 1915 to coordinate the nation’s aeronautical research. The committee opened a research laboratory at Langley Field in 1920. By the late 1930s, however, European nations, Germany in particular, were building faster and higher flying aircraft. The NACA decided to expand with a new Ames Aeronautical Laboratory dedicated to high-speed flight and the AERL to handle engine-related research. The NACA examined a number of Midwest locations for its new engine lab before deciding on Cleveland. At the time, Cleveland possessed the nation’s most advanced airport, several key aircraft manufacturing companies, and was home to the National Air Races. Local officials were also able to broker a deal with the power company to discount its electricity rates if the large wind tunnels were operated overnight. The decision was made in October 1940, and the groundbreaking alongside the airport took place on January 23, 1941. From left to right: William Hopkins, John Berry, Ray Sharp, Frederick Crawford, George Brett, Edward Warner, Sydney Kraus, Edward Blythin, and George Lewis

Laboratory Directed Research and Development Program FY 2006

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hansen

2007-03-08

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operatemore » unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness.« less

Laboratory Directed Research and Development Program Assessment for FY 2016

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hatton, Diane; Flynn, Liz

2017-03-31

Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy in accordance with DOE Order 413.2C, and this report fulfills that requirement.

Laboratory Directed Research and Development Program Assessment for FY 2017

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderson, Jack; Flynn, Liz

Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy in accordance with DOE Order 413.2C. This report fulfills that requirement.

Collaboration Agreement | Frederick National Laboratory for Cancer Research

Cancer.gov

A Collaboration Agreement is appropriate for research collaboration involving intellectual and material contributions by the Frederick National Laboratory and external partner(s). It is useful for proof-of-concept studies. Includes brief re

Guidelines for Biosafety Training Programs for Workers Assigned to BSL-3 Research Laboratories.

PubMed

Homer, Lesley C; Alderman, T Scott; Blair, Heather Ann; Brocard, Anne-Sophie; Broussard, Elaine E; Ellis, Robert P; Frerotte, Jay; Low, Eleanor W; McCarthy, Travis R; McCormick, Jessica M; Newton, JeT'Aime M; Rogers, Francine C; Schlimgen, Ryan; Stabenow, Jennifer M; Stedman, Diann; Warfield, Cheryl; Ntiforo, Corrie A; Whetstone, Carol T; Zimmerman, Domenica; Barkley, Emmett

2013-03-01

The Guidelines for Biosafety Training Programs for Workers Assigned to BSL-3 Research Laboratories were developed by biosafety professionals who oversee training programs for the 2 national biocontainment laboratories (NBLs) and the 13 regional biocontainment laboratories (RBLs) that participate in the National Institute of Allergy and Infectious Diseases (NIAID) NBL/RBL Network. These guidelines provide a general training framework for biosafety level 3 (BSL-3) high-containment laboratories, identify key training concepts, and outline training methodologies designed to standardize base knowledge, understanding, and technical competence of laboratory personnel working in high-containment laboratories. Emphasis is placed on building a culture of risk assessment-based safety through competency training designed to enhance understanding and recognition of potential biological hazards as well as methods for controlling these hazards. These guidelines may be of value to other institutions and academic research laboratories that are developing biosafety training programs for BSL-3 research.

Naval Research Laboratory Major Facilities 2008

DTIC Science & Technology

2008-10-01

Development Laboratory • Secure Supercomputing Facility • CBD/Tilghman Island IR Field Evaluation Facility • Ultra-Short-Pulse Laser Effects Research...EMI Test Facility • Proximity Operations Testbed GENERAL INFORMATION • Maps EX EC U TI V E D IR EC TO RA TE Code 1100 – Institute for Nanoscience...facility: atomic force microscope (AFM); benchtop transmission electron microscope (TEM); cascade probe station; critical point dryer ; dual beam focused

Laboratory challenges conducting international clinical research in resource-limited settings.

PubMed

Fitzgibbon, Joseph E; Wallis, Carole L

2014-01-01

There are many challenges to performing clinical research in resource-limited settings. Here, we discuss several of the most common laboratory issues that must be addressed. These include issues relating to organization and personnel, laboratory facilities and equipment, standard operating procedures, external quality assurance, shipping, laboratory capacity, and data management. Although much progress has been made, innovative ways of addressing some of these issues are still very much needed.

The Genomics Education Partnership: Successful Integration of Research into Laboratory Classes at a Diverse Group of Undergraduate Institutions

PubMed Central

Shaffer, Christopher D.; Alvarez, Consuelo; Bailey, Cheryl; Barnard, Daron; Bhalla, Satish; Chandrasekaran, Chitra; Chandrasekaran, Vidya; Chung, Hui-Min; Dorer, Douglas R.; Du, Chunguang; Eckdahl, Todd T.; Poet, Jeff L.; Frohlich, Donald; Goodman, Anya L.; Gosser, Yuying; Hauser, Charles; Hoopes, Laura L.M.; Johnson, Diana; Jones, Christopher J.; Kaehler, Marian; Kokan, Nighat; Kopp, Olga R.; Kuleck, Gary A.; McNeil, Gerard; Moss, Robert; Myka, Jennifer L.; Nagengast, Alexis; Morris, Robert; Overvoorde, Paul J.; Shoop, Elizabeth; Parrish, Susan; Reed, Kelynne; Regisford, E. Gloria; Revie, Dennis; Rosenwald, Anne G.; Saville, Ken; Schroeder, Stephanie; Shaw, Mary; Skuse, Gary; Smith, Christopher; Smith, Mary; Spana, Eric P.; Spratt, Mary; Stamm, Joyce; Thompson, Jeff S.; Wawersik, Matthew; Wilson, Barbara A.; Youngblom, Jim; Leung, Wilson; Buhler, Jeremy; Mardis, Elaine R.; Lopatto, David

2010-01-01

Genomics is not only essential for students to understand biology but also provides unprecedented opportunities for undergraduate research. The goal of the Genomics Education Partnership (GEP), a collaboration between a growing number of colleges and universities around the country and the Department of Biology and Genome Center of Washington University in St. Louis, is to provide such research opportunities. Using a versatile curriculum that has been adapted to many different class settings, GEP undergraduates undertake projects to bring draft-quality genomic sequence up to high quality and/or participate in the annotation of these sequences. GEP undergraduates have improved more than 2 million bases of draft genomic sequence from several species of Drosophila and have produced hundreds of gene models using evidence-based manual annotation. Students appreciate their ability to make a contribution to ongoing research, and report increased independence and a more active learning approach after participation in GEP projects. They show knowledge gains on pre- and postcourse quizzes about genes and genomes and in bioinformatic analysis. Participating faculty also report professional gains, increased access to genomics-related technology, and an overall positive experience. We have found that using a genomics research project as the core of a laboratory course is rewarding for both faculty and students. PMID:20194808

Research and Laboratory Instruction--An Experiment in Teaching

ERIC Educational Resources Information Center

Kramm, Kenneth R.

1976-01-01

Describes an attempt to incorporate research into laboratory work in an introductory ecology class and a senior seminar. The investigation involves the examination of rhythms of food consumption and circadian activities in humans. (GS)

Contact Us | Frederick National Laboratory for Cancer Research

Cancer.gov

E-mail:fnlwebsite@nih.gov Phone:(301) 846-1000 Postal Mail: Frederick National Laboratory for Cancer Research P.O. Box B Frederick, MD 21702-1201 Human Resources Office of Recruitment (301) 846-5362 Jim

Global Impact | Frederick National Laboratory for Cancer Research

Cancer.gov

Through its direct support of clinical research, Frederick National Laboratory activities are not limited to national programs. The labis actively involved in more than 400 domestic and international studies related to cancer; influenza, HIV, E

Locations Accessible | Frederick National Laboratory for Cancer Research

Cancer.gov

The Frederick National Laboratory for Cancer Research campus is located 50 miles northwest of Washington, D.C., and 50 miles west of Baltimore, Maryland, in Frederick, Maryland.Operations and Technical Support contractor Leidos Biomedical Resea

Summary of the 2017 Alcohol and Immunology Research Interest Group (AIRIG) meeting.

PubMed

Hulsebus, Holly J; Curtis, Brenda J; Molina, Patricia E; Afshar, Majid; Boule, Lisbeth A; Morris, Niya; Keshavarzian, Ali; Kolls, Jay K; Yeligar, Samantha M; Price, Michael E; Wyatt, Todd A; Choudhry, Mashkoor A; Kovacs, Elizabeth J

2018-06-01

On June 24, 2017, the 22nd annual Alcohol and Immunology Research Interest Group (AIRIG) meeting was held as a satellite conference during the annual Research Society on Alcoholism (RSA) Scientific Meeting in Denver, Colorado. The 2017 meeting focused broadly on mechanisms that link alcohol to tissue injury and inflammation, and how this research can be translated to improve human health. Two plenary sessions composed the meeting, which first explored the association between alcohol and trauma/tissue injury, and finished with a discussion of alcohol and mucosal inflammation. The presentations encompassed diverse areas of alcohol research, from effects on the brain, to airway and pulmonary systems, to gut barrier disruption. The discussions also thoughtfully highlighted how current laboratory and clinical research can be used to prevent or treat alcohol-related morbidity and mortality. Copyright © 2017 Elsevier Inc. All rights reserved.

Steam Plant at the Aircraft Engine Research Laboratory

NASA Image and Video Library

1945-09-21

The Steam Plant at the National Advisory Committee for Aeronautics (NACA) Aircraft Engine Research Laboratory supplies steam to the major test facilities and office buildings. Steam is used for the Icing Research Tunnel's spray system and the Engine Research Building’s desiccant air dryers. In addition, its five boilers supply heat to various buildings and the cafeteria. Schirmer-Schneider Company built the $141,000 facility in the fall of 1942, and it has been in operation ever since.

Mapping Maize Genes: A Series of Research-Based Laboratory Exercises

ERIC Educational Resources Information Center

Makarevitch, Irina; Kralich, Elizabeth

2011-01-01

Open-ended, inquiry-based multiweek laboratory exercises are the key elements to increasing students' understanding and retention of the major biological concepts. Including original research into undergraduate teaching laboratories has also been shown to motivate students and improve their learning. Here, we present a series of original…

Integrating teaching and research in the field and laboratory settings

NASA Astrophysics Data System (ADS)

Wang, L.; Kaseke, K. F.; Daryanto, S.; Ravi, S.

2015-12-01

Field observations and laboratory measurements are great ways to engage students and spark students' interests in science. Typically these observations are separated from rigorous classroom teaching. Here we assessed the potential of integrating teaching and research in the field and laboratory setting in both US and abroad and worked with students without strong science background to utilize simple laboratory equipment and various environmental sensors to conduct innovative projects. We worked with students in Namibia and two local high school students in Indianapolis to conduct leaf potential measurements, soil nutrient extraction, soil infiltration measurements and isotope measurements. The experience showed us the potential of integrating teaching and research in the field setting and working with people with minimum exposure to modern scientific instrumentation to carry out creative projects.

2015 Fermilab Laboratory Directed Research & Development Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wester, W.

2016-05-26

The Fermi National Accelerator Laboratory (FNAL) is conducting a Laboratory Directed Research and Development (LDRD) program. Fiscal year 2015 represents the first full year of LDRD at Fermilab and includes seven projects approved mid-year in FY14 and six projects approved in FY15. One of the seven original projects has been completed just after the beginning of FY15. The implementation of LDRD at Fermilab is captured in the approved Fermilab 2015 LDRD Annual Program Plan. In FY15, the LDRD program represents 0.64% of Laboratory funding. The scope of the LDRD program at Fermilab will be established over the next couple ofmore » years where a portfolio of about 20 on-going projects representing approximately between 1% and 1.5% of the Laboratory funding is anticipated. This Annual Report focuses on the status of the current projects and provides an overview of the current status of LDRD at Fermilab.« less

Michigan/Air Force Research Laboratory (AFRL) Collaborative Center in Control Science (MACCCS)

DTIC Science & Technology

2016-09-01

AFRL-RQ-WP-TR-2016-0139 MICHIGAN/AIR FORCE RESEARCH LABORATORY (AFRL) COLLABORATIVE CENTER IN CONTROL SCIENCE (MACCCS) Anouck Girard...Final 18 April 2007 – 30 September 2016 4. TITLE AND SUBTITLE MICHIGAN/AIR FORCE RESEARCH LABORATORY (AFRL) COLLABORATIVE CENTER IN CONTROL SCIENCE...and amplify an internationally recognized center of excellence in control science research and education, through interaction between the faculty and

Smart Electronic Laboratory Notebooks for the NIST Research Environment.

PubMed

Gates, Richard S; McLean, Mark J; Osborn, William A

2015-01-01

Laboratory notebooks have been a staple of scientific research for centuries for organizing and documenting ideas and experiments. Modern laboratories are increasingly reliant on electronic data collection and analysis, so it seems inevitable that the digital revolution should come to the ordinary laboratory notebook. The most important aspect of this transition is to make the shift as comfortable and intuitive as possible, so that the creative process that is the hallmark of scientific investigation and engineering achievement is maintained, and ideally enhanced. The smart electronic laboratory notebooks described in this paper represent a paradigm shift from the old pen and paper style notebooks and provide a host of powerful operational and documentation capabilities in an intuitive format that is available anywhere at any time.

Smart Electronic Laboratory Notebooks for the NIST Research Environment

PubMed Central

Gates, Richard S.; McLean, Mark J.; Osborn, William A.

2015-01-01

Laboratory notebooks have been a staple of scientific research for centuries for organizing and documenting ideas and experiments. Modern laboratories are increasingly reliant on electronic data collection and analysis, so it seems inevitable that the digital revolution should come to the ordinary laboratory notebook. The most important aspect of this transition is to make the shift as comfortable and intuitive as possible, so that the creative process that is the hallmark of scientific investigation and engineering achievement is maintained, and ideally enhanced. The smart electronic laboratory notebooks described in this paper represent a paradigm shift from the old pen and paper style notebooks and provide a host of powerful operational and documentation capabilities in an intuitive format that is available anywhere at any time. PMID:26958447

The Virtual Robotics Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kress, R.L.; Love, L.J.

The growth of the Internet has provided a unique opportunity to expand research collaborations between industry, universities, and the national laboratories. The Virtual Robotics Laboratory (VRL) is an innovative program at Oak Ridge National Laboratory (ORNL) that is focusing on the issues related to collaborative research through controlled access of laboratory equipment using the World Wide Web. The VRL will provide different levels of access to selected ORNL laboratory secondary education programs. In the past, the ORNL Robotics and Process Systems Division has developed state-of-the-art robotic systems for the Army, NASA, Department of Energy, Department of Defense, as well asmore » many other clients. After proof of concept, many of these systems sit dormant in the laboratories. This is not out of completion of all possible research topics. but from completion of contracts and generation of new programs. In the past, a number of visiting professors have used this equipment for their own research. However, this requires that the professor, and possibly his/her students, spend extended periods at the laboratory facility. In addition, only a very exclusive group of faculty can gain access to the laboratory and hardware. The VRL is a tool that enables extended collaborative efforts without regard to geographic limitations.« less

Dental Laboratory Technology. Project Report Phase I with Research Findings.

ERIC Educational Resources Information Center

Sappe', Hoyt; Smith, Debra S.

This report provides results of Phase I of a project that researched the occupational area of dental laboratory technology, established appropriate committees, and conducted task verification. These results are intended to guide development of a program designed to train dental laboratory technicians. Section 1 contains general information:…

Frontiers: Research highlights 1946-1996 [50th Anniversary Edition. Argonne National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-12-31

This special edition of 'Frontiers' commemorates Argonne National Laboratory's 50th anniversary of service to science and society. America's first national laboratory, Argonne has been in the forefront of U.S. scientific and technological research from its beginning. Past accomplishments, current research, and future plans are highlighted.

Frontiers: Research Highlights 1946-1996 [50th Anniversary Edition. Argonne National Laboratory

DOE R&D Accomplishments Database

1996-01-01

This special edition of 'Frontiers' commemorates Argonne National Laboratory's 50th anniversary of service to science and society. America's first national laboratory, Argonne has been in the forefront of U.S. scientific and technological research from its beginning. Past accomplishments, current research, and future plans are highlighted.

Material Transfer Agreement (MTA) | Frederick National Laboratory for Cancer Research

Cancer.gov

Material Transfer Agreements are appropriate for exchange of materials into or out of the Frederick National Laboratory for research or testing purposes, with no collaborative research by parties involving the materials.

76 FR 1212 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-07

... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board Panel for Eligibility; Notice of Meeting The Department of Veterans Affairs (VA) gives notice under the Public Law 92-463 (Federal Advisory...

75 FR 57833 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-22

... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board; Notice of Meetings The Department of Veterans Affairs gives notice under the Public Law 92-463 (Federal Advisory Committee Act) that...

76 FR 66367 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-26

... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board; Notice of Meetings The Department of Veterans Affairs gives notice under the Public Law 92-463 (Federal Advisory Committee Act) that...

77 FR 26069 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-02

... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board, Notice of Meeting Amendment The Department of Veterans Affairs (VA) gives notice under the Public Law 92-463 (Federal Advisory Committee Act...

76 FR 79273 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-21

... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board Panel for Eligibility, Notice of Meeting The Department of Veterans Affairs (VA) gives notice under Public Law 92-463 (Federal Advisory...

Summer Research Experiences with a Laboratory Tokamak

NASA Astrophysics Data System (ADS)

Farley, N.; Mauel, M.; Navratil, G.; Cates, C.; Maurer, D.; Mukherjee, S.; Shilov, M.; Taylor, E.

1998-11-01

Columbia University's Summer Research Program for Secondary School Science Teachers seeks to improve middle and high school student understanding of science. The Program enhances science teachers' understanding of the practice of science by having them participate for two consecutive summers as members of laboratory research teams led by Columbia University faculty. In this poster, we report the research and educational activities of two summer internships with the HBT-EP research tokamak. Research activities have included (1) computer data acquisition and the representation of complex plasma wave phenomena as audible sounds, and (2) the design and construction of pulsed microwave systems to experience the design and testing of special-purpose equipment in order to achieve a specific technical goal. We also present an overview of the positive impact this type of plasma research involvement has had on high school science teaching.

The Laboratory Course Assessment Survey: A Tool to Measure Three Dimensions of Research-Course Design

PubMed Central

Corwin, Lisa A.; Runyon, Christopher; Robinson, Aspen; Dolan, Erin L.

2015-01-01

Course-based undergraduate research experiences (CUREs) are increasingly being offered as scalable ways to involve undergraduates in research. Yet few if any design features that make CUREs effective have been identified. We developed a 17-item survey instrument, the Laboratory Course Assessment Survey (LCAS), that measures students’ perceptions of three design features of biology lab courses: 1) collaboration, 2) discovery and relevance, and 3) iteration. We assessed the psychometric properties of the LCAS using established methods for instrument design and validation. We also assessed the ability of the LCAS to differentiate between CUREs and traditional laboratory courses, and found that the discovery and relevance and iteration scales differentiated between these groups. Our results indicate that the LCAS is suited for characterizing and comparing undergraduate biology lab courses and should be useful for determining the relative importance of the three design features for achieving student outcomes. PMID:26466990

Including Everyone in Research: The Burton Street Research Group

ERIC Educational Resources Information Center

Abell, Simon; Ashmore, Jackie; Wilson, Dorothy; Beart, Suzie; Brownley, Peter; Butcher, Adam; Clarke, Zara; Combes, Helen; Francis, Errol; Hayes, Stefan; Hemmingham, Ian; Hicks, Kerry; Ibraham, Amina; Kenyon, Elinor; Lee, Darren; McClimens, Alex; Collins, Michelle; Newton, John; Wilson, Dorothy

2007-01-01

In our paper we talk about what it is like to be a group of people with and without learning disabilities researching together. We describe the process of starting and maintaining the research group and reflect on the obstacles that we have come across, and the rewards such research has brought us. Lastly we put forward some ideas about the role…

Argonne National Laboratory Annual Report of Laboratory Directed Research and Development program activities FY 2011.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Office of The Director)

As a national laboratory Argonne concentrates on scientific and technological challenges that can only be addressed through a sustained, interdisciplinary focus at a national scale. Argonne's eight major initiatives, as enumerated in its strategic plan, are Hard X-ray Sciences, Leadership Computing, Materials and Molecular Design and Discovery, Energy Storage, Alternative Energy and Efficiency, Nuclear Energy, Biological and Environmental Systems, and National Security. The purposes of Argonne's Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel technical concepts, enhance the Laboratory's research and development (R and D) capabilities, and pursue its strategic goals. projects are selectedmore » from proposals for creative and innovative R and D studies that require advance exploration before they are considered to be sufficiently developed to obtain support through normal programmatic channels. Among the aims of the projects supported by the LDRD Program are the following: establishment of engineering proof of principle, assessment of design feasibility for prospective facilities, development of instrumentation or computational methods or systems, and discoveries in fundamental science and exploratory development.« less

FY04 Engineering Technology Reports Laboratory Directed Research and Development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sharpe, R M

2005-01-27

This report summarizes the science and technology research and development efforts in Lawrence Livermore National Laboratory's Engineering Directorate for FY2004, and exemplifies Engineering's more than 50-year history of developing the technologies needed to support the Laboratory's missions. Engineering has been a partner in every major program and project at the Laboratory throughout its existence and has prepared for this role with a skilled workforce and the technical resources developed through venues like the Laboratory Directed Research and Development Program (LDRD). This accomplishment is well summarized by Engineering's mission: ''Enable program success today and ensure the Laboratory's vitality tomorrow''. Engineering's investmentmore » in technologies is carried out through two programs, the ''Tech Base'' program and the LDRD program. LDRD is the vehicle for creating those technologies and competencies that are cutting edge. These require a significant level of research or contain some unknown that needs to be fully understood. Tech Base is used to apply technologies to a Laboratory need. The term commonly used for Tech Base projects is ''reduction to practice''. Therefore, the LDRD report covered here has a strong research emphasis. Areas that are presented all fall into those needed to accomplish our mission. For FY2004, Engineering's LDRD projects were focused on mesoscale target fabrication and characterization, development of engineering computational capability, material studies and modeling, remote sensing and communications, and microtechnology and nanotechnology for national security applications. Engineering's five Centers, in partnership with the Division Leaders and Department Heads, are responsible for guiding the long-term science and technology investments for the Directorate. The Centers represent technologies that have been identified as critical for the present and future work of the Laboratory, and are chartered to develop their

US Naval Research Laboratory's Current Space Photovoltaic Experiemtns

NASA Astrophysics Data System (ADS)

Jenkins, Phillip; Walters, Robert; Messenger, Scott; Krasowski, Michael

2008-09-01

The US Naval Research Laboratory (NRL) has a rich history conducting space photovoltaic (PV) experiments starting with Vanguard I, the first solar powered satellite in 1958. Today, NRL in collaboration with the NASA Glenn Research Center, is engaged in three flight experiments demonstrating a wide range of PV technologies in both LEO and HEO orbits. The Forward Technology Solar Cell Experiment (FTSCE)[1], part of the 5th Materials on the International Space Station Experiment (MISSE-5), flew for 13 months on the International Space Station in 2005-2006. The FTSCE provided in-situ I-V monitoring of advanced III-V multi-junction cells and laboratory prototypes of thin film and other next generation technologies. Two experiments under development will provide more opportunities to demonstrate advanced solar cells and characterization electronics that are easily integrated on a wide variety of spacecraft bus architectures.

Optical laboratory facilities at the Finnish Meteorological Institute - Arctic Research Centre

NASA Astrophysics Data System (ADS)

Lakkala, Kaisa; Suokanerva, Hanne; Matti Karhu, Juha; Aarva, Antti; Poikonen, Antti; Karppinen, Tomi; Ahponen, Markku; Hannula, Henna-Reetta; Kontu, Anna; Kyrö, Esko

2016-07-01

This paper describes the laboratory facilities at the Finnish Meteorological Institute - Arctic Research Centre (FMI-ARC, http://fmiarc.fmi.fi). They comprise an optical laboratory, a facility for biological studies, and an office. A dark room has been built, in which an optical table and a fixed lamp test system are set up, and the electronics allow high-precision adjustment of the current. The Brewer spectroradiometer, NILU-UV multifilter radiometer, and Analytical Spectral Devices (ASD) spectroradiometer of the FMI-ARC are regularly calibrated or checked for stability in the laboratory. The facilities are ideal for responding to the needs of international multidisciplinary research, giving the possibility to calibrate and characterize the research instruments as well as handle and store samples.

New working paradigms in research laboratories.

PubMed

Keighley, Wilma; Sewing, Andreas

2009-07-01

Work in research laboratories, especially within centralised functions in larger organisations, is changing fast. With easier access to external providers and Contract Research Organisations, and a focus on budgets and benchmarking, scientific expertise has to be complemented with operational excellence. New concepts, globally shared projects and restricted resources highlight the constraints of traditional operating models working from Monday to Friday and nine to five. Whilst many of our scientists welcome this new challenge, organisations have to enable and foster a more business-like mindset. Organisational structures, remuneration, as well as systems in finance need to be adapted to build operations that are best-in-class rather than merely minimising negative impacts of current organisational structures.

Research and Teaching: The Impact of a Four-Step Laboratory Pedagogical Framework on Biology Students' Perceptions of Laboratory Skills, Knowledge, and Interest in Research

ERIC Educational Resources Information Center

McLaughlin, Jacqueline Shea; Favre, David E.; Weinstein, Suzanne E.; Goedhart, Christine M.

2017-01-01

Authentic undergraduate research laboratory experiences are essential to aid in the implementation of science education reform mandates and to effectively train a new generation of biology students. Here we present assessment data on a unique four-step laboratory pedagogical framework that allows students to develop scientific thinking and…

Laboratory directed research and development 2006 annual report.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Westrich, Henry Roger

2007-03-01

This report summarizes progress from the Laboratory Directed Research and Development (LDRD) program during fiscal year 2006. In addition to a programmatic and financial overview, the report includes progress reports from 430 individual R&D projects in 17 categories.

The Effect of Grouping by Formal Reasoning Ability, Formal Reasoning Ability Levels, Group Size, and Gender on Achievement in Laboratory Chemistry.

ERIC Educational Resources Information Center

Moody, Judith D.; Gifford, Vernon D.

This study investigated the grouping effect on student achievement in a chemistry laboratory when homogeneous and heterogeneous formal reasoning ability, high and low levels of formal reasoning ability, group sizes of two and four, and homogeneous and heterogeneous gender were used for grouping factors. The sample consisted of all eight intact…

78 FR 28292 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-14

... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board; Notice of Meetings; Amendment The Department of Veterans Affairs (VA) gives notice under the Federal Advisory Committee Act, 5 U.S.C. App...

[Study of continuous quality improvement for clinical laboratory processes via the platform of Hospital Group].

PubMed

Song, Wenqi; Shen, Ying; Peng, Xiaoxia; Tian, Jian; Wang, Hui; Xu, Lili; Nie, Xiaolu; Ni, Xin

2015-05-26

The program of continuous quality improvement in clinical laboratory processes for complete blood count (CBC) was launched via the platform of Beijing Children's Hospital Group in order to improve the quality of pediatric clinical laboratories. Fifteen children's hospitals of Beijing Children's Hospital group were investigated using the method of Chinese adapted continuous quality improvement with PDCA (Plan-Do-Check-Action). The questionnaire survey and inter-laboratory comparison was conducted to find the existing problems, to analyze reasons, to set forth quality targets and to put them into practice. Then, targeted training was conducted to 15 children's hospitals and the second questionnaire survey, self examinations by the clinical laboratories was performed. At the same time, the Group's online internal quality control platform was established. Overall effects of the program were evaluated so that lay a foundation for the next stage of PDCA. Both quality of control system documents and CBC internal quality control scheme for all of clinical laboratories were improved through this program. In addition, standardization of performance verification was also improved, especially with the comparable verification rate of precision and internal laboratory results up to 100%. In terms of instrument calibration and mandatory diagnostic rates, only three out of the 15 hospitals (20%) failed to pass muster in 2014 from 46.67% (seven out of the 15 hospitals) in 2013. The abnormal data of intraday precision variance coefficients of the five CBC indicator parameters (WBC, RBC, Hb, Plt and Hct) of all the 15 laboratories accounted for 1.2% (2/165) in 2014, a marked decrease from 9.6% (14/145) in 2013. While the number of the hospitals using only one horizontal quality control object for daily quality control has dropped to three from five. The 15 hospitals organized a total of 263 times of training in 2014 from 101 times in 2013, up 160%. The quality improvement program for

The Los Alamos Scientific Laboratory - An Isolated Nuclear Research Establishment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bradbury, Norris E.; Meade, Roger Allen

Early in his twenty-five year career as the Director of the Los Alamos Scientific Laboratory, Norris Bradbury wrote at length about the atomic bomb and the many implications the bomb might have on the world. His themes were both technical and philosophical. In 1963, after nearly twenty years of leading the nation’s first nuclear weapons laboratory, Bradbury took the opportunity to broaden his writing. In a paper delivered to the International Atomic Energy Agency’s symposium on the “Criteria in the Selection of Sites for the Construction of Reactors and Nuclear Research Centers,” Bradbury took the opportunity to talk about themore » business of nuclear research and the human component of operating a scientific laboratory. This report is the transcript of his talk.« less

Unbridle biomedical research from the laboratory cage

PubMed Central

Lahvis, Garet P

2017-01-01

Many biomedical research studies use captive animals to model human health and disease. However, a surprising number of studies show that the biological systems of animals living in standard laboratory housing are abnormal. To make animal studies more relevant to human health, research animals should live in the wild or be able to roam free in captive environments that offer a natural range of both positive and negative experiences. Recent technological advances now allow us to study freely roaming animals and we should make use of them. PMID:28661398

A critical Action Research approach to curriculum development in a laboratory-based chemical engineering course

NASA Astrophysics Data System (ADS)

White, Scott R.

This dissertation is a report of an attempt to critically evaluate a novel laboratory course from within the context of a chemical engineering curriculum. The research was done in a college classroom-laboratory setting, entrenched in the everydayness of classroom activities. All of the students, instructors, and educational researchers were knowing participants in this Action Research study. The students, a mixture of juniors, seniors, & graduate students, worked together on semester-long projects in groups that were mixed by age, gender and academic level. Qualitative techniques were used to gather different forms of representations of the students and instructors' experiences. Emergent patterns from the data gave strength to emergent knowledge claims that informed the instructors and the researcher about what the students were learning about performing experimental work and communicating results with their peers and instructor. The course challenged and in some cases changed the conceptions of instruction previously held by the students and the instructors. The course did not proceed without problems, yet the majority of these problems were overcome by the design of the course. Assertions and recommendations for improvement and application to other educational contexts are suggested.

Methodology in diagnostic laboratory test research in clinical chemistry and clinical chemistry and laboratory medicine.

PubMed

Lumbreras-Lacarra, Blanca; Ramos-Rincón, José Manuel; Hernández-Aguado, Ildefonso

2004-03-01

The application of epidemiologic principles to clinical diagnosis has been less developed than in other clinical areas. Knowledge of the main flaws affecting diagnostic laboratory test research is the first step for improving its quality. We assessed the methodologic aspects of articles on laboratory tests. We included articles that estimated indexes of diagnostic accuracy (sensitivity and specificity) and were published in Clinical Chemistry or Clinical Chemistry and Laboratory Medicine in 1996, 2001, and 2002. Clinical Chemistry has paid special attention to this field of research since 1996 by publishing recommendations, checklists, and reviews. Articles were identified through electronic searches in Medline. The strategy combined the Mesh term "sensitivity and specificity" (exploded) with the text words "specificity", "false negative", and "accuracy". We examined adherence to seven methodologic criteria used in the study by Reid et al. (JAMA1995;274:645-51) of papers published in general medical journals. Three observers evaluated each article independently. Seventy-nine articles fulfilled the inclusion criteria. The percentage of studies that satisfied each criterion improved from 1996 to 2002. Substantial improvement was observed in reporting of the statistical uncertainty of indices of diagnostic accuracy, in criteria based on clinical information from the study population (spectrum composition), and in avoidance of workup bias. Analytical reproducibility was reported frequently (68%), whereas information about indeterminate results was rarely provided. The mean number of methodologic criteria satisfied showed a statistically significant increase over the 3 years in Clinical Chemistry but not in Clinical Chemistry and Laboratory Medicine. The methodologic quality of the articles on diagnostic test research published in Clinical Chemistry and Clinical Chemistry and Laboratory Medicine is comparable to the quality observed in the best general medical journals

The Central Importance of Laboratories for Reducing Waste in Biomedical Research.

PubMed

Stroth, Nikolas

2016-12-01

The global biomedical research enterprise is driving substantial advances in medicine and healthcare. Yet it appears that the enterprise is rather wasteful, falling short of its true innovative potential. Suggested reasons are manifold and involve various stakeholders, such that there is no single remedy. In the present paper, I will argue that laboratories are the basic working units of the biomedical research enterprise and an important site of action for corrective intervention. Keeping laboratories relatively small will enable better training and mentoring of individual scientists, which in turn will yield better performance of the scientific workforce. The key premise of this argument is that people are at the heart of the successes and failures of biomedical research, yet the human dimension of science has been unduly neglected in practice. Renewed focus on the importance of laboratories and their constituent scientists is one promising approach to reducing waste and increasing efficiency within the biomedical research enterprise.

Aprendizaje en grupo en el laboratorio de idiomas (Group Learning in the Language Laboratory).

ERIC Educational Resources Information Center

Monteverde G., Luisa

1971-01-01

This paper describes a teaching method, presently in the experimental stage, that advocates the use of a programed instruction model in the language laboratory, with students working in homogeneous groups of three. The author describes the technical construction and operation of the language laboratory which allows three students to work together…

Laboratory Directed Research and Development LDRD-FY-2011

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dena Tomchak

2012-03-01

This report provides a summary of the research conducted at the Idaho National Laboratory (INL) during Fiscal Year (FY) 2011. This report demonstrates the types of cutting edge research the INL is performing to help ensure the nation's energy security. The research conducted under this program is aligned with our strategic direction, benefits the Department of Energy (DOE) and is in compliance with DOE order 413.2B. This report summarizes the diverse research and development portfolio with emphasis on the DOE Office of Nuclear Energy (DOE-NE) mission, encompassing both advanced nuclear science and technology and underlying technologies.

The NASA Lewis Research Center High Temperature Fatigue and Structures Laboratory

NASA Technical Reports Server (NTRS)

Mcgaw, M. A.; Bartolotta, P. A.

1987-01-01

The physical organization of the NASA Lewis Research Center High Temperature Fatigue and Structures Laboratory is described. Particular attention is given to uniaxial test systems, high cycle/low cycle testing systems, axial torsional test systems, computer system capabilities, and a laboratory addition. The proposed addition will double the floor area of the present laboratory and will be equipped with its own control room.

Cryptosporidiosis outbreak at an academic animal research laboratory-Colorado, 2014.

PubMed

Hancock-Allen, Jessica; Alden, Nisha B; Cronquist, Alicia B

2017-02-01

After cryptosporidiosis was reported in three workers caring for preweaned calves at an academic research laboratory, we sought to identify cases, determine risk factors, and implement control measures. A cryptosporidiosis case was defined as diarrhea duration ≥72 hr, abdominal cramps, or vomiting in an animal research laboratory worker during July 14-July 31. A confirmed case had laboratory evidence of Cryptosporidium infection. Staff were interviewed regarding illness, potential exposures, training, and personal protective equipment (PPE) standard operating procedures (SOPs). The cryptosporidiosis attack rate (AR) was 74% (20/27); five were laboratory-confirmed. Median job training was 2 hr including respiratory-fit testing. No SOPs existed for doffing PPE. AR for workers who removed their gloves first was 84% (16/19) compared with 20% (1/5) for workers who removed gloves last (risk ratio = 4.2; P < 0.02). This outbreak highlights the importance of adequate training, enforced proper PPE procedures, and promoting a culture of safety. Am. J. Ind. Med. 60:208-214, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

The Automated Primate Research Laboratory (APRL)

NASA Technical Reports Server (NTRS)

Pace, N.; Smith, G. D.

1972-01-01

A description is given of a self-contained automated primate research laboratory to study the effects of weightlessness on subhuman primates. Physiological parameters such as hemodynamics, respiration, blood constituents, waste, and diet and nutrition are analyzed for abnormalities in the simulated space environment. The Southeast Asian pig-tailed monkey (Macaca nemistrina) was selected for the experiments owing to its relative intelligence and learning capacity. The objective of the program is to demonstrate the feasibility of a man-tended primate space flight experiment.

Nanotechnology Laboratory Collaborates with Army to Develop Botulism Vaccine | Frederick National Laboratory for Cancer Research

Cancer.gov

The Nanotechnology Characterization Laboratory (NCL) is collaborating with the Army to develop a candidate vaccine against botulism. Under a collaboration agreement between the National Cancer Institute and the U.S. Army Medical Research Institute of

Argonne National Laboratory annual report of Laboratory Directed Research and Development Program Activities FY 2009.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Office of the Director

2010-04-09

I am pleased to submit Argonne National Laboratory's Annual Report on its Laboratory Directed Research and Development (LDRD) activities for fiscal year 2009. Fiscal year 2009 saw a heightened focus by DOE and the nation on the need to develop new sources of energy. Argonne scientists are investigating many different sources of energy, including nuclear, solar, and biofuels, as well as ways to store, use, and transmit energy more safely, cleanly, and efficiently. DOE selected Argonne as the site for two new Energy Frontier Research Centers (EFRCs) - the Institute for Atom-Efficient Chemical Transformations and the Center for Electrical Energymore » Storage - and funded two other EFRCs to which Argonne is a major partner. The award of at least two of the EFRCs can be directly linked to early LDRD-funded efforts. LDRD has historically seeded important programs and facilities at the lab. Two of these facilities, the Advanced Photon Source and the Center for Nanoscale Materials, are now vital contributors to today's LDRD Program. New and enhanced capabilities, many of which relied on LDRD in their early stages, now help the laboratory pursue its evolving strategic goals. LDRD has, since its inception, been an invaluable resource for positioning the Laboratory to anticipate, and thus be prepared to contribute to, the future science and technology needs of DOE and the nation. During times of change, LDRD becomes all the more vital for facilitating the necessary adjustments while maintaining and enhancing the capabilities of our staff and facilities. Although I am new to the role of Laboratory Director, my immediate prior service as Deputy Laboratory Director for Programs afforded me continuous involvement in the LDRD program and its management. Therefore, I can attest that Argonne's program adhered closely to the requirements of DOE Order 413.2b and associated guidelines governing LDRD. Our LDRD program management continually strives to be more efficient. In addition

CSI flight experiment projects of the Naval Research Laboratory

NASA Technical Reports Server (NTRS)

Fisher, Shalom

1993-01-01

The Naval Research Laboratory (NRL) is involved in an active program of CSI flight experiments. The first CSI flight experiment of the Naval Research Laboratory, the Low Power Atmospheric Compensation Experiment (LACE) dynamics experiment, has successfully measured vibrations of an orbiting satellite with a ground-based laser radar. The observations, made on January 7, 8 and 10, 1991, represent the first ever measurements of this type. In the tests, a narrowband heterodyne CO2 laser radar, operating at a wavelength of 10.6 microns, detected vibration induced differential-Doppler signatures of the LACE satellite. Power spectral densities of forced oscillations and modal frequencies and damping rates of free-damped vibrations were obtained and compared with finite element structural models of the LACE system. Another manifested flight experiment is the Advanced Controls Technology Experiment (ACTEX) designed to demonstrate active and passive damping with piezo-electric (PZT) sensors and actuators. This experiment was developed under the management of the Air Force Phillips Laboratory with integration of the experiment at NRL. It is to ride as a secondary, or 'piggyback,' experiment on a future Navy satellite.

CSI flight experiment projects of the Naval Research Laboratory

NASA Astrophysics Data System (ADS)

Fisher, Shalom

1993-02-01

The Naval Research Laboratory (NRL) is involved in an active program of CSI flight experiments. The first CSI flight experiment of the Naval Research Laboratory, the Low Power Atmospheric Compensation Experiment (LACE) dynamics experiment, has successfully measured vibrations of an orbiting satellite with a ground-based laser radar. The observations, made on January 7, 8 and 10, 1991, represent the first ever measurements of this type. In the tests, a narrowband heterodyne CO2 laser radar, operating at a wavelength of 10.6 microns, detected vibration induced differential-Doppler signatures of the LACE satellite. Power spectral densities of forced oscillations and modal frequencies and damping rates of free-damped vibrations were obtained and compared with finite element structural models of the LACE system. Another manifested flight experiment is the Advanced Controls Technology Experiment (ACTEX) designed to demonstrate active and passive damping with piezo-electric (PZT) sensors and actuators. This experiment was developed under the management of the Air Force Phillips Laboratory with integration of the experiment at NRL. It is to ride as a secondary, or 'piggyback,' experiment on a future Navy satellite.

Educational-research laboratory "electric circuits" on the base of digital technologies

NASA Astrophysics Data System (ADS)

Koroteyev, V. I.; Florentsev, V. V.; Florentseva, N. I.

2017-01-01

The problem of research activity of trainees' activation in the educational-research laboratory "Electric Circuits" using innovative methodological solutions and digital technologies is considered. The main task is in creation of the unified experimental research information-educational environment "Electrical Engineering". The problems arising during the developing and application of the modern software and hardware, experimental and research stands and digital control and measuring systems are presented. This paper presents the main stages of development and creation of educational-research laboratory "Electrical Circuits" at the Department of Electrical Engineering of NRNU MEPhI. The authors also consider the analogues of the described research complex offered by various educational institutions and companies. The analysis of their strengths and weaknesses, on which the advantages of the proposed solution are based, is held.

Learning in the Laboratory: How Group Assignments Affect Motivation and Performance

ERIC Educational Resources Information Center

Belanger, John R.

2016-01-01

Team projects can optimize educational resources in a laboratory, but also create the potential for social loafing. Allowing students to choose their own groups could increase their motivation to learn and improve academic performance. To test this hypothesis, final grades and feedback from students were compared for the same course in two…

National Research Council Research Associateships Program with Methane Hydrates Fellowships Program/National Energy Technology Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Basques, Eric O.

2014-03-20

This report summarizes work carried out over the period from July 5, 2005-January 31, 2014. The work was carried out by the National Research Council Research Associateships Program of the National Academies, under the US Department of Energy's National Energy Technology Laboratory (NETL) program. This Technical Report consists of a description of activity from 2005 through 2014, broken out within yearly timeframes, for NRC/NETL Associateships researchers at NETL laboratories which includes individual tenure reports from Associates over this time period. The report also includes individual tenure reports from associates over this time period. The report also includes descriptions of programmore » promotion efforts, a breakdown of the review competitions, awards offered, and Associate's activities during their tenure.« less

Strategic Plan for the ORD National Exposure Research Laboratory (NERL)

EPA Science Inventory

The National Exposure Research Laboratory (NERL) has a valued reputation for supporting the Agency’s mission of protecting human health and the environment with multidisciplinary expertise that brings cutting-edge research and technology to address critical exposure questions and...

Pilot-Scale Laboratory Instruction for Chemical Engineering: The Specific Case of the Pilot-Unit Leading Group

ERIC Educational Resources Information Center

Billet, Anne-Marie; Camy, Severine; Coufort-Saudejaud, Carole

2010-01-01

This paper presents an original approach for Chemical Engineering laboratory teaching that is currently applied at INP-ENSIACET (France). This approach, referred to as "pilot-unit leading group" is based on a partial management of the laboratories by the students themselves who become temporarily in charge of one specific laboratory. In…

Using the Human Systems Simulation Laboratory at Idaho National Laboratory for Safety Focused Research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Joe, Jeffrey .C; Boring, Ronald L.

Under the United States (U.S.) Department of Energy (DOE) Light Water Reactor Sustainability (LWRS) program, researchers at Idaho National Laboratory (INL) have been using the Human Systems Simulation Laboratory (HSSL) to conduct critical safety focused Human Factors research and development (R&D) for the nuclear industry. The LWRS program has the overall objective to develop the scientific basis to extend existing nuclear power plant (NPP) operating life beyond the current 60-year licensing period and to ensure their long-term reliability, productivity, safety, and security. One focus area for LWRS is the NPP main control room (MCR), because many of the instrumentation andmore » control (I&C) system technologies installed in the MCR, while highly reliable and safe, are now difficult to replace and are therefore limiting the operating life of the NPP. This paper describes how INL researchers use the HSSL to conduct Human Factors R&D on modernizing or upgrading these I&C systems in a step-wise manner, and how the HSSL has addressed a significant gap in how to upgrade systems and technologies that are built to last, and therefore require careful integration of analog and new advanced digital technologies.« less

Potato-related research at USDA-ARS laboratories in Washington and Idaho

USDA-ARS?s Scientific Manuscript database

Potato-related research currently being conducted at three USDA-ARS laboratories in Idaho and Washington is reviewed. Objectives of research programs at the Temperate Tree Fruit & Vegetable Research Unit (Wapato, WA), the Irrigated Agriculture Research and Extension Center (Prosser, WA), and the Sm...

NATIONAL HEALTH AND ENVIRONMENTAL EFFECTS RESEARCH LABORATORY - ACCOMPLISHMENTS FOR FY 2001

EPA Science Inventory

This Annual Report showcases some of the scientific activities of the National Health and Environmental Effects Research Laboratory (NHEERL) in various health and environmental effects research areas. Where appropriate, the contributions of other collaborating research organizat...

"It takes a village" to raise research productivity: impact of a Trauma Interdisciplinary Group for Research at an urban, Level 1 trauma center.

PubMed

NeSmith, Elizabeth G; Medeiros, Regina S; Ferdinand, Colville H B; Hawkins, Michael L; Holsten, Steven B; Zhu, Haidong; Dong, Yanbin

2013-07-01

Few interdisciplinary research groups include basic scientists, pharmacists, therapists, nutritionists, laboratory technicians, as well as trauma patients and families, in addition to clinicians. Increasing interprofessional diversity within scientific teams working to improve trauma care is a goal of national organizations and federal funding agencies such as the National Institutes of Health (NIH). This article describes the design, implementation, and outcomes of a Trauma Interdisciplinary Group for Research (TIGR) at a Level 1 trauma center as it relates to increasing research productivity, with specific examples excerpted from an ongoing NIH-funded study. We used a pretest/posttest design with objectives aimed at measuring increases in research productivity following a targeted intervention. A SWOT (strengths, weaknesses, opportunities, and threats) analysis was used to develop the intervention, which included research skill-building activities, accomplished by adding multidisciplinary investigators to an existing NIH-funded project. The NIH project aimed to test the hypothesis that accelerated biologic aging from chronic stress increases baseline inflammation and reduces inflammatory response to trauma (projected n = 150). Pre-TIGR/post-TIGR data related to participant screening, recruitment, consent, and research processes were compared. Research productivity was measured through abstracts, publications, and investigator-initiated projects. Research products increased from 12 to 42 (approximately 400%). Research proposals for federal funding increased from 0 to 3, with success rate of 66%. Participant screenings for the NIH-funded study increased from 40 to 313. Consents increased from 14 to 70. Laboratory service fees were reduced from $300 per participant to $5 per participant. Adding diversity to our scientific team via TIGR was exponentially successful in (1) improving research productivity, (2) reducing research costs, and (3) increasing research

Safety Issues in Agricultural Education Laboratories: A Synthesis of Research.

ERIC Educational Resources Information Center

Dyer, James E.; Andreasen, Randall J.

1999-01-01

Synthesis of research on safety in agricultural education laboratories found most research focused on agricultural mechanics. Labs appeared to be potentially hazardous places, and teachers have inadequate knowledge of safety laws and ways to provide a safe working environment. (SK)

A Hybrid Integrated Laboratory and Inquiry-Based Research Experience: Replacing Traditional Laboratory Instruction with a Sustainable Student-Led Research Project

ERIC Educational Resources Information Center

Hartings, Matthew R.; Fox, Douglas M.; Miller, Abigail E.; Muratore, Kathryn E.

2015-01-01

The Department of Chemistry at American University has replaced its junior- and senior-level laboratory curriculum with two, two-semester long, student-led research projects as part of the department's American Chemical Society-accredited program. In the first semester of each sequence, a faculty instructor leads the students through a set of…

Geoscience Research at Storm Peak (GRASP), a year-long program providing exceptional field research for a diverse group of undergraduate students

NASA Astrophysics Data System (ADS)

Hallar, A. G.; McCubbin, I. B.; Hallar, B. L.; Stockwell, W.; Kittelson, J.; Lopez, J.

2008-12-01

Geoscience Research at Storm Peak (GRASP) was designed to engage students from underrepresented groups through a partnership between Minority Serving Institutions and the University of Nevada, Reno (UNR). The program exposed the GRASP participants to potential careers in the geosciences, provided them with an authentic research experience at Storm Peak Laboratory (SPL), and gave them an opportunity to explore dynamic scenery. Undergraduate students from Howard University, Colorado State at Pueblo, Leman College, and SUNY Oneonta, gathered at SPL in June of 2008 via funding from the National Science Foundation Opportunity for Enhancing Diversity. The students reunited at Howard University in November to present the results of their research project. Throughout the year-long GRASP program students encountered the scientific process-creating a hypothesis, collecting and analyzing data, and presenting their results. Results from surveys, focus groups, and individual interviews will be discussed in this presentation.

A comparison of traditional physical laboratory and computer-simulated laboratory experiences in relation to engineering undergraduate students' conceptual understandings of a communication systems topic

NASA Astrophysics Data System (ADS)

Javidi, Giti

2005-07-01

This study was designed to investigate an alternative to the use of traditional physical laboratory activities in a communication systems course. Specifically, this study examined whether as an alternative, computer simulation is as effective as physical laboratory activities in teaching college-level electronics engineering education students about the concepts of signal transmission, modulation and demodulation. Eighty undergraduate engineering students participated in the study, which was conducted at a southeastern four-year university. The students were randomly assigned to two groups. The groups were compared on understanding the concepts, remembering the concepts, completion time of the lab experiments and perception toward the laboratory experiments. The physical group's (n = 40) treatment was to conduct laboratory experiments in a physical laboratory. The students in this group used equipment in a controlled electronics laboratory. The Simulation group's (n = 40) treatment was to conduct similar experiments in a PC laboratory. The students in this group used a simulation program in a controlled PC lab. At the completion of the treatment, scores on a validated conceptual test were collected once after the treatment and again three weeks after the treatment. Attitude surveys and qualitative study were administered at the completion of the treatment. The findings revealed significant differences, in favor of the simulation group, between the two groups on both the conceptual post-test and the follow-up test. The findings also revealed significant correlation between simulation groups' attitude toward the simulation program and their post-test scores. Moreover, there was a significant difference between the two groups on their attitude toward their laboratory experience in favor of the simulation group. In addition, there was significant difference between the two groups on their lab completion time in favor of the simulation group. At the same time, the

LABORATORY DIRECTED RESEARCH AND DEVELOPMENT ANNUAL REPORT TO THE DEPARTMENT OF ENERGY - DECEMBER 2006

DOE Office of Scientific and Technical Information (OSTI.GOV)

FOX, K.J.

Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's total annual budget has averaged about $460 million. There are about 2,500 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE)more » annually in March, as required by DOE Order 413.2B, ''Laboratory Directed Research and Development,'' April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy National Nuclear Security Administration Laboratories dated June 13, 2006. In accordance this is our Annual Report in which we describe the Purpose, Approach, Technical Progress and Results, and Specific Accomplishments of all LDRD projects that received funding during Fiscal Year 2006.« less

Laboratory directed research and development program FY 1997

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-03-01

This report compiles the annual reports of Laboratory Directed Research and Development projects supported by the Berkeley Lab. Projects are arranged under the following topical sections: (1) Accelerator and fusion research division; (2) Chemical sciences division; (3) Computing Sciences; (4) Earth sciences division; (5) Environmental energy technologies division; (6) life sciences division; (7) Materials sciences division; (8) Nuclear science division; (9) Physics division; (10) Structural biology division; and (11) Cross-divisional. A total of 66 projects are summarized.

Middle/high school students in the research laboratory: A summer internship program emphasizing the interdisciplinary nature of biology.

PubMed

McMiller, Tracee; Lee, Tameshia; Saroop, Ria; Green, Tyra; Johnson, Casonya M

2006-03-01

We describe an eight-week summer Young Scientist in Training (YSIT) internship program involving middle and high school students. This program exposed students to current basic research in molecular genetics, while introducing or reinforcing principles of the scientific method and demonstrating the uses of mathematics and chemistry in biology. For the laboratory-based program, selected students from Baltimore City Schools working in groups of three were teamed with undergraduate research assistants at Morgan State University. Teams were assigned a project that was indirectly related to our laboratory research on the characterization of gene expression in Caenorhabditis elegans. At the end of the program, teams prepared posters detailing their accomplishments, and presented their findings to parents and faculty members during a mini-symposium. The posters were also submitted to the respective schools and the interns were offered a presentation of their research at local high school science fairs. Copyright © 2006 International Union of Biochemistry and Molecular Biology, Inc.

Identifying and Addressing Challenges to Research in University Laboratory Preschools

ERIC Educational Resources Information Center

File, Nancy

2012-01-01

Research Findings: This essay offers a review of challenges that university laboratory preschools face in providing a site for research that fits with other components of the program mission. An argument is made to consider paradigm shifts in research questions and methods that move away from traditions within the fields that study children's…

General Henry Arnold Visits the Aircraft Engine Research Laboratory

NASA Image and Video Library

1944-11-21

General Henry “Hap” Arnold, Commander of the US Army Air Forces during World War II, addresses the staff at the National Advisory Committee for Aeronautics (NACA) Aircraft Engine Research Laboratory on November 9, 1944. Arnold told the employees assembled in the hangar, “You’ve got a dual task. You’ve got a job ahead of you to keep the army and the navy air forces equipped with the finest equipment that you can for this war. You also have the job of looking forward into the future and starting now those developments, those experiments, that are going to keep us in our present situation—ahead of the world in the air. And that is quite a large order, and I leave it right in your laps.” Arnold served on the NACA’s Executive Committee in Washington from 1938 to 1944 and had been a strong advocate for the creation of the new engine research facility in Cleveland. Arnold believed in continual research and development. He pressed the nation’s aviation leaders to pursue the new jet engine technology, while simultaneously pushing to increase the performance of the nation’s largest piston engine for the B–29 Superfortress program. The general’s hectic wartime agenda limited his visit to the Cleveland laboratory to just a few hours, but he toured several of the NACA’s new test facilities including the Static Jet Propulsion Laboratory, the Icing Research Tunnel, and a B–24 Liberator in the hangar.

Undergraduate Introductory Quantitative Chemistry Laboratory Course: Interdisciplinary Group Projects in Phytoremediation

ERIC Educational Resources Information Center

Van Engelen, Debra L.; Suljak, Steven W.; Hall, J. Patrick; Holmes, Bert E.

2007-01-01

The laboratory course around the phytoremediation is designed to develop both individual skills and promote cooperative learning while starting students work on projects in a specific area of environmental chemistry and analysis. Many research-active undergraduate institutions have developed courses, which are interdisciplinary in nature that…

Conducting Research With Community Groups.

PubMed

Doornbos, Mary Molewyk; Ayoola, Adejoke; Topp, Robert; Zandee, Gail Landheer

2015-10-01

Nurse scientists are increasingly recognizing the necessity of conducting research with community groups to effectively address complex health problems and successfully translate scientific advancements into the community. Although several barriers to conducting research with community groups exist, community-based participatory research (CBPR) has the potential to mitigate these barriers. CBPR has been employed in programs of research that respond in culturally sensitive ways to identify community needs and thereby address current health disparities. This article presents case studies that demonstrate how CBPR principles guided the development of (a) a healthy body weight program for urban, underserved African American women; (b) a reproductive health educational intervention for urban, low-income, underserved, ethnically diverse women; and (c) a pilot anxiety/depression intervention for urban, low-income, underserved, ethnically diverse women. These case studies illustrate the potential of CBPR as an orientation to research that can be employed effectively in non-research-intensive academic environments. © The Author(s) 2015.

Conducting Research with Community Groups

PubMed Central

Doornbos, Mary Molewyk; Ayoola, Adejoke; Topp, Robert; Zandee, Gail Landheer

2016-01-01

Nurse scientists are increasingly recognizing the necessity of conducting research with community groups to effectively address complex health problems and successfully translate scientific advancements into the community. While several barriers to conducting research with community groups exist, community based participatory research (CBPR) has the potential to mitigate these barriers. CBPR has been employed in programs of research that respond in culturally sensitive ways to identify community needs and thereby address current health disparities. This manuscript presents case studies that demonstrate how CBPR principles guided the development of: (a) a healthy body weight program for urban, underserved African-American women, (b) a reproductive health educational intervention for urban, low-income, underserved, ethnically diverse women, and (c) a pilot anxiety/depression intervention for urban, low-income, underserved, ethnically diverse women. These case studies illustrate the potential of CBPR as an orientation to research that can be employed effectively in non-research intensive academic environments. PMID:25724557

A 13-week research-based biochemistry laboratory curriculum.

PubMed

Lefurgy, Scott T; Mundorff, Emily C

2017-09-01

Here, we present a 13-week research-based biochemistry laboratory curriculum designed to provide the students with the experience of engaging in original research while introducing foundational biochemistry laboratory techniques. The laboratory experience has been developed around the directed evolution of an enzyme chosen by the instructor, with mutations designed by the students. Ideal enzymes for this curriculum are able to be structurally modeled, solubly expressed, and monitored for activity by UV/Vis spectroscopy, and an example curriculum for haloalkane dehalogenase is given. Unique to this curriculum is a successful implementation of saturation mutagenesis and high-throughput screening of enzyme function, along with bioinformatics analysis, homology modeling, structural analysis, protein expression and purification, polyacrylamide gel electrophoresis, UV/Vis spectroscopy, and enzyme kinetics. Each of these techniques is carried out using a novel student-designed mutant library or enzyme variant unique to the lab team and, importantly, not described previously in the literature. Use of a well-established set of protocols promotes student data quality. Publication may result from the original student-generated hypotheses and data, either from the class as a whole or individual students that continue their independent projects upon course completion. © 2017 by The International Union of Biochemistry and Molecular Biology, 45(5):437-448, 2017. © 2017 The International Union of Biochemistry and Molecular Biology.

Through Microgravity and Towards the Stars: Microgravity and Strategic Research at Marshall's Biological and Physical Space Research Laboratory

NASA Technical Reports Server (NTRS)

Curreri, Peter A.

2003-01-01

The Microgravity and Strategic research at Marshall s Biological and Physical Space Research Laboratory will be reviewed. The environment in orbit provides a unique opportunity to study Materials Science and Biotechnology in the absence of sedimentation and convection. There are a number of peer-selected investigations that have been selected to fly on the Space Station that have been conceived and are led by Marshall s Biological and Physical Research Laboratory s scientists. In addition to Microgravity research the Station will enable research in "Strategic" Research Areas that focus on enabling humans to live, work, and explore the solar system safely. New research in Radiation Protection, Strategic Molecular Biology, and In-Space Fabrication will be introduced.

NATIONAL RISK MANAGEMENT RESEARCH LABORATORY: PROVIDING SOLUTIONS FOR A BETTER TOMORROW

EPA Science Inventory

This small, two-fold flyer contains general information introducing EPA's National Risk Management Research Laboratory and its research program. The key overarching areas of research described are: Protection of drinking water; control of air pollution; pollution prevention and e...

Senior Research Connects Students with a Living Laboratory As Part of an Integrated Crop and Livestock System

NASA Astrophysics Data System (ADS)

Senturklu, Songul; Landblom, Douglas; Brevik, Eric C.

2015-04-01

highest expenses in beef cattle production. Senior research investigating the impact of livestock integration and multi-species cover crop grown within the crop rotation is studying changes in soil attributes resulting from the crop-animal integration by measuring bulk density and in-season soil fertility in the crop rotation. These responses are further contrasted with results from within the crop rotation and responses from perennial native range. Students that become engaged in the research represent a broad cross section of the consuming public and include high school junior and senior students, college undergraduate students that conduct research projects, postdoctoral research scientists engaged in senior level research, agricultural extension educators, and finally, farmer and rancher businessmen. The integrated nature of the research provides a wealth of learning opportunities for these various groups. For the high school students, visits to the living laboratory increase awareness and introduces students to a potential career path in agriculture, natural resource fields, and the many allied vocational fields that support agriculture. When college undergraduate students visit the living laboratory, they seek to address a researchable question or a problem in agriculture, while fulfilling requirements for graduation by conducting a research project. Because postdoctoral students want to be actively engaged in research and advanced learning, they are interested in conducting research in the living laboratory that can be published in peer reviewed journals. Agricultural extension educators, who advise farmers and ranchers, are looking for research results from the living laboratory that can be convey to their constituents. Farmers and ranchers participate in workshop events that give them face-to-face learning opportunities that they can use to effect change in their farm and ranch businesses. Each of these demographic groups are unique in their interest in the

Frederick National Laboratory, National Cancer Institute of Mexico to Offer Training Fellowships | Frederick National Laboratory for Cancer Research

Cancer.gov

FREDERICK, Md. -- The Frederick National Laboratory for Cancer Research will extend its scientific mentoring across international borders for the first time by offering postdoctoral research fellowships to scientists under an agreement with the Nati

Avoiding biohazards in medical, veterinary and research laboratories.

PubMed

Grizzle, W E; Fredenburgh, J

2001-07-01

Personnel in medical, veterinary or research laboratories may be exposed to a wide variety of pathogens that range from deadly to debilitating. For some of these pathogens, no treatment is available, and in other cases the treatment does not fully control the disease. It is important that personnel in laboratories that process human or microbiological specimens follow universal precautions when handling tissues, cells, or microbiological specimens owing to the increasing numbers of individuals infected with hepatitis C and HIV in the US and the possibility that an individual may be asymptomatic when a specimen is obtained. Similar precautions must be followed in laboratories that use animal tissues owing to the possibility of exposure to agents that are pathogenic in humans. Personnel with conditions associated with immunosuppression should evaluate carefully whether or not specific laboratory environments put them at increased risk of disease. We offer here some general approaches to identifying biohazards and to minimizing the potential risk of exposure. The issues discussed can be used to develop a general safety program as required by regulatory or accrediting agencies, including the Occupational Safety and Health Administration.

Effects of light at night on laboratory animals and research outcomes.

PubMed

Emmer, Kathryn M; Russart, Kathryn L G; Walker, William H; Nelson, Randy J; DeVries, A Courtney

2018-06-28

Light has substantial influences on the physiology and behavior of most laboratory animals. As such, lighting conditions within animal rooms are potentially significant and often underappreciated variables within experiments. Disruption of the light/dark cycle, primarily by exposing animals to light at night (LAN), disturbs biological rhythms and has widespread physiological consequences because of mechanisms such as melatonin suppression, sympathetic stimulation, and altered circadian clock gene expression. Thus, attention to the lighting environment of laboratory animals and maintaining consistency of a light/dark cycle is imperative for study reproducibility. Light intensity, as well as wavelength, photoperiod, and timing, are all important variables. Although modern rodent facilities are designed to facilitate appropriate light cycling, there are simple ways to modify rooms to prevent extraneous light exposure during the dark period. Attention to lighting conditions of laboratory animals by both researchers and research care staff ensures best practices for maintaining animal welfare, as well as reproducibility of research results. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Laboratory directed research and development. FY 1995 progress report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vigil, J.; Prono, J.

1996-03-01

This document presents an overview of Laboratory Directed Research and Development Programs at Los Alamos. The nine technical disciplines in which research is described include materials, engineering and base technologies, plasma, fluids, and particle beams, chemistry, mathematics and computational science, atmic and molecular physics, geoscience, space science, and astrophysics, nuclear and particle physics, and biosciences. Brief descriptions are provided in the above programs.

André Cournand, Bellevue's Cardiopulmonary Laboratory, and Research on Heart Failure.

PubMed

Braunwald, Eugene

2018-02-01

In 1954-1955, the author served as a research fellow in the cardiopulmonary laboratory led by André Cournand at Bellevue Hospital in New York. Cournand was a pulmonary physiologist and a professor of medicine at Columbia University. In his quest to obtain mixed venous blood to calculate pulmonary blood flow, he catheterized the right atrium, right ventricle, and pulmonary artery in patients and also measured the pressures in these chambers. Cournand and his collaborators soon appreciated the enormous potential of cardiac catheterization in deepening the understanding of cardiovascular pathophysiology. After a series of groundbreaking studies, Cournand and his coworker Dickinson Richards, as well as German physician Werner Forssmann, were awarded a Nobel Prize in 1956. Cournand's laboratory, his work habits, and his rigorous approach to science are described, as well as the stimulation the author received during the author's fellowship. As a result, the author went on to extend to the left side of the heart the observations that the Cournand group had conducted in the right heart. Also, the author continued Cournand's work on heart failure by developing techniques to measure ventricular function in patients and to describe the neurohumoral changes that occur in human heart failure.

Integrating teaching and authentic research in the field and laboratory settings

NASA Astrophysics Data System (ADS)

Daryanto, S.; Wang, L.; Kaseke, K. F.; Ravi, S.

2016-12-01

Typically authentic research activities are separated from rigorous classroom teaching. Here we assessed the potential of integrating teaching and research activities both in the field and in the laboratory. We worked with students from both US and abroad without strong science background to utilize advanced environmental sensors and statistical tool to conduct innovative projects. The students include one from Namibia and two local high school students in Indianapolis (through Project SEED, Summer Experience for the Economically Disadvantaged). They conducted leaf potential measurements, isotope measurements and meta-analysis. The experience showed us the great potential of integrating teaching and research in both field and laboratory settings.

Redefining Authentic Research Experiences in Introductory Biology Laboratories and Barriers to Their Implementation

ERIC Educational Resources Information Center

Spell, Rachelle M.; Guinan, Judith A.; Miller, Kristen R.; Beck, Christopher W.

2014-01-01

Incorporating authentic research experiences in introductory biology laboratory classes would greatly expand the number of students exposed to the excitement of discovery and the rigor of the scientific process. However, the essential components of an authentic research experience and the barriers to their implementation in laboratory classes are…

Introducing Students to Psychological Research: General Psychology as a Laboratory Course

ERIC Educational Resources Information Center

Thieman, Thomas J.; Clary, E. Gil; Olson, Andrea M.; Dauner, Rachel C.; Ring, Erin E.

2009-01-01

For 6 years, we have offered an integrated weekly laboratory focusing on research methods as part of our general psychology course. Through self-report measures and controlled comparisons, we found that laboratory projects significantly increase students' knowledge and comfort level with scientific approaches and concepts, sustain interest in…

Practices for caring in nursing: Brazilian research groups.

PubMed

Erdmann, A L; de Andrade, S R; de Mello, A L Ferreira; Klock, P; do Nascimento, K C; Koerich, M Santos; Backes, D Stein

2011-09-01

The present study considers the production of knowledge and the interactions in the environment of research and their relationships in the system of caring in nursing and health. To elaborate a theoretical model of the organization of the practices used for caring, based on the experiences made by the research groups of administration and management in nursing, in Brazil. The study is based on grounded theory. Twelve leaders of research groups, working as professors in public universities in the south and the south-east of Brazil, distributed in sample groups, were interviewed. The core phenomenon 'research groups of administration and management in nursing: arrangements and interactions in the system of caring in nursing' was derived from the categories: conceptual bases and contexts of the research groups; experiencing interactions in the research groups; functionality of the research groups; and outputs of the research groups. The research groups are integrated in the system of caring in nursing. The activities of the Brazilian administration and management in nursing research groups are process oriented and in a process of constant renovation, socially relevant, operate in a complex scenario and contribute to the advancement of the organizations of the system of caring in nursing through strengthening the connection among academia, service and community. © 2011 The Authors. International Nursing Review © 2011 International Council of Nurses.

Laboratory of Viral Diseases Guest Researcher Seminar Series | Center for Cancer Research

Cancer.gov

Laboratory of Viral Diseases Guest Researcher Seminar Series New Epigenetic Regulators of HIV Latency Speaker: Melanie Ott, M.D., Ph.D, Senior Investigator & Professor of Medicine Gladstone Institutes & University of California Building 33, Main Conference Room 1N09 Main NIH CAMPUS *BLDG 33 is a secure facility, please allow time to pass through security.

Zoonoses of occupational health importance in contemporary laboratory animal research.

PubMed

Hankenson, F Claire; Johnston, Nancy A; Weigler, Benjamin J; Di Giacomo, Ronald F

2003-12-01

In contemporary laboratory animal facilities, workplace exposure to zoonotic pathogens, agents transmitted to humans from vertebrate animals or their tissues, is an occupational hazard. The primary (e.g., macaques, pigs, dogs, rabbits, mice, and rats) and secondary species (e.g., sheep, goats, cats, ferrets, and pigeons) of animals commonly used in biomedical research, as classified by the American College of Laboratory Animal Medicine, are established or potential hosts for a large number of zoonotic agents. Diseases included in this review are principally those wherein a risk to biomedical facility personnel has been documented by published reports of human cases in laboratory animal research settings, or under reasonably similar circumstances. Diseases are listed alphabetically, and each section includes information about clinical disease, transmission, occurrence, and prevention in animal reservoir species and humans. Our goal is to provide a resource for veterinarians, health-care professionals, technical staff, and administrators that will assist in the design and on-going evaluation of institutional occupational health and safety programs.

Lawrence Livermore National Laboratory FY 2016 Laboratory Directed Research and Development Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Al-Ayat, R.; Gard, E.; Sketchley, J.

The LDRD annual report for FY2016 consists of two parts: The Overview. This section contains a broad description of the LDRD Program, highlights of recent accomplishments and awards, Program statistics, and the LDRD portfolio-management processes. Project Reports. Project reports are submitted by all principal investigators at the end of the fiscal year. The length and depth of the report depends on the project’s lifecycle. For projects that will be continuing the following year, the principal investigator submits a continuing project report, which is a brief update containing descriptions of the goals, scope, motivation, relevance (to DOE/NNSA and Livermore mission areas),more » and technical progress achieved in FY16, as well as a list of selected publications and presentations that resulted from the research. For projects that concluded in FY16, a more detailed final report is provided that is technical in nature and includes the background, objectives, scientific approach, accomplishments, and impacts on the Laboratory missions, as well as a list of publications and presentations that resulted from the research. Project reports are listed under their research topics and organized by year and type, such as exploratory research (ER), feasibility study (FS), laboratory-wide competition (LW), and strategic initiative (SI). Each project is assigned a unique tracking code, an identifier that consists of three elements. The first is the fiscal year in which the project began, the second represents the project type, and the third identifies the serial number of the project for that fiscal year. For example, 16-ERD-100 means the project is an exploratory research project that began in FY16. The three-digit number (100) represents the serial number for the project.« less

What We Do | Frederick National Laboratory for Cancer Research

Cancer.gov

The Frederick National Laboratory is the only U.S. national lab wholly focused on research, technology, and collaboration in the biomedical sciences- working to discover, to innovate, and to improve human health. We accelerate progress against can

Establishment of a Laboratory for Biofuels Research at the University of Kentucky

DOE Office of Scientific and Technical Information (OSTI.GOV)

Crocker, Mark; Crofcheck, Czarena; Andrews, Rodney

2013-03-29

This project was aimed at the development of the biofuels industry in Kentucky by establishing a laboratory to develop improved processes for biomass utilization. The facility is based at the University of Kentucky Center for Applied Energy Research and the Department of Biosystems and Agricultural Engineering, and constitutes an “open” laboratory, i.e., its equipment is available to other Kentucky researchers working in the area. The development of this biofuels facility represents a significant expansion of research infrastructure, and will provide a lasting resource for biobased research endeavors at the University of Kentucky. In order to enhance the laboratory's capabilities andmore » contribute to on-going biofuels research at the University of Kentucky, initial research at the laboratory has focused on the following technical areas: (i) the identification of algae strains suitable for oil production, utilizing flue gas from coal-fired power plants as a source of CO 2; (ii) the conversion of algae to biofuels; and (iii) the development of methods for the analysis of lignin and its deconstruction products. Highlights from these activities include the development of catalysts for the upgrading of lipids to hydrocarbons by means of decarboxylation/decarbonylation (deCOx), a study of bio-oil production from the fast pyrolysis of algae (Scenedesmus), and the application of pyrolytic gas chromatography coupled with mass spectrometry (Py-GC-MS) to the characterization of high lignin biomass feedstocks.« less

Laboratory directed research and development: Annual report to the Department of Energy

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-12-01

As one of the premier scientific laboratories of the DOE, Brookhaven must continuously foster the development of new ideas and technologies, promote the early exploration and exploitation of creative and innovative concepts, and develop new fundable R and D projects and programs. At Brookhaven National Laboratory one such method is through its Laboratory Directed Research and Development Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community, fostering new science and technology ideas, which is a major factor in achievingmore » and maintaining staff excellence and a means to address national needs within the overall mission of the DOE and BNL. The Project Summaries with their accomplishments are described in this report. Aside from leading to new fundable or promising programs and producing especially noteworthy research, they have resulted in numerous publications in various professional and scientific journals and presentations at meetings and forums.« less

Cyclotron laboratory of the Institute for Nuclear Research and Nuclear Energy

NASA Astrophysics Data System (ADS)

Tonev, D.; Goutev, N.; Georgiev, L. S.

2016-06-01

An accelerator laboratory is presently under construction in Sofia at the Institute for Nuclear Research and Nuclear Energy, Bulgarian Academy of Sciences. The laboratory will use a TR24 type of cyclotron, which provides a possibility to accelerate a proton beam with an energy of 15 to 24 MeV and current of up to 0.4 mA. An accelerator with such parameters allows to produce a large variety of radioisotopes for development of radiopharmaceuticals. The most common radioisotopes that could be produced with such a cyclotron are PET isotopes like: 11C, 13N, 15O, 18F, 124I, 64Cu, 68Ge/68Ga, and SPECT isotopes like: 123I, 111In, 67Ga, 57Co, 99m Tc. Our aim is to use the cyclotron facility for research in the fields of radiopharmacy, radiochemistry, radiobiology, nuclear physics, solid state physics, applied research, new materials and for education in all these fields including nuclear energy. The building of the laboratory will be constructed nearby the Institute for Nuclear Research and Nuclear Energy and the cyclotron together with all the equipment needed will be installed there.

Research Collaborations Between Universities and Department of Defense Laboratories

DTIC Science & Technology

2014-07-31

collaboration and often combines government, industry , and university partners. Must be competed. Medium to long term Yes Yes Yes Yes...can reach out to third parties such as industry or Federally Funded Research and Development Centers (FFRDCs) without the having to go through...position at DOD laboratories. Students learn about research that is important to the DOD, and university- industry collaborations are a great way to

Developing an organizing framework to guide nursing research in the Children’s Oncology Group (COG)

PubMed Central

Kelly, Katherine Patterson; Hooke, Mary C.; Ruccione, Kathleen; Landier, Wendy; Haase, Joan

2014-01-01

Objectives To describe the development and application of an organizing research framework to guide COG Nursing research. Data Sources Research articles, reports and meeting minutes Conclusion An organizing research framework helps to outline research focus and articulate the scientific knowledge being produced by nurses in the pediatric cooperative group. Implication for Nursing Practice The use of an organizing framework for COG nursing research can facilitate clinical nurses’ understanding of how children and families sustain or regain optimal health when faced with a pediatric cancer diagnosis through interventions designed to promote individual and family resilience. The Children’s Oncology Group (COG) is the sole National Cancer Institute (NCI)-supported cooperative pediatric oncology clinical trials group and the largest organization in the world devoted exclusively to pediatric cancer research. It was founded in 2000 following the merger of the four legacy NCI-supported pediatric clinical trials groups (Children’s Cancer Group [CCG], Pediatric Oncology Group [POG], National Wilms Tumor Study Group, and Intergroup Rhabdomyosarcoma Study Group). The COG currently has over 200 member institutions across North America, Australia, New Zealand and Europe and a multidisciplinary membership of over 8,000 pediatric, radiation, and surgical oncologists, nurses, clinical research associates, pharmacists, behavioral scientists, pathologists, laboratory scientists, patient/parent advocates and other pediatric cancer specialists. The COG Nursing Discipline was formed from the merger of the legacy CCG and POG Nursing Committees, and current membership exceeds 2000 registered nurses. The discipline has a well-developed infrastructure that promotes nursing involvement throughout all levels of the organization, including representation on disease, protocol, scientific, executive and other administrative committees (e.g., nominating committee, data safety monitoring

Space Electric Research Test in the Electric Propulsion Laboratory

NASA Image and Video Library

1964-06-21

Technicians prepare the Space Electric Research Test (SERT-I) payload for a test in Tank Number 5 of the Electric Propulsion Laboratory at the National Aeronautics and Space Administration (NASA) Lewis Research Center. Lewis researchers had been studying different methods of electric rocket propulsion since the mid-1950s. Harold Kaufman created the first successful engine, the electron bombardment ion engine, in the early 1960s. These electric engines created and accelerated small particles of propellant material to high exhaust velocities. Electric engines have a very small amount of thrust, but once lofted into orbit by workhorse chemical rockets, they are capable of small, continuous thrust for periods up to several years. The electron bombardment thruster operated at a 90-percent efficiency during testing in the Electric Propulsion Laboratory. The package was rapidly rotated in a vacuum to simulate its behavior in space. The SERT-I mission, launched from Wallops Island, Virginia, was the first flight test of Kaufman’s ion engine. SERT-I had one cesium engine and one mercury engine. The suborbital flight was only 50 minutes in duration but proved that the ion engine could operate in space. The Electric Propulsion Laboratory included two large space simulation chambers, one of which is seen here. Each uses twenty 2.6-foot diameter diffusion pumps, blowers, and roughing pumps to remove the air inside the tank to create the thin atmosphere. A helium refrigeration system simulates the cold temperatures of space.

CNR LARA project, Italy: Airborne laboratory for environmental research

NASA Technical Reports Server (NTRS)

Bianchi, R.; Cavalli, R. M.; Fiumi, L.; Marino, C. M.; Pignatti, S.

1995-01-01

The increasing interest for the environmental problems and the study of the impact on the environment due to antropic activity produced an enhancement of remote sensing applications. The Italian National Research Council (CNR) established a new laboratory for airborne hyperspectral imaging, the LARA Project (Laboratorio Aero per Ricerche Ambientali - Airborne Laboratory for Environmental Research), equipping its airborne laboratory, a CASA-212, mainly with the Daedalus AA5000 MIVIS (Multispectral Infrared and Visible Imaging Spectrometer) instrument. MIVIS's channels, spectral bandwidths, and locations are chosen to meet the needs of scientific research for advanced applications of remote sensing data. MIVIS can make significant contributions to solving problems in many diverse areas such as geologic exploration, land use studies, mineralogy, agricultural crop studies, energy loss analysis, pollution assessment, volcanology, forest fire management and others. The broad spectral range and the many discrete narrow channels of MIVIS provide a fine quantization of spectral information that permits accurate definition of absorption features from a variety of materials, allowing the extraction of chemical and physical information of our environment. The availability of such a hyperspectral imager, that will operate mainly in the Mediterranean area, at the present represents a unique opportunity for those who are involved in environmental studies and land-management to collect systematically large-scale and high spectral-spatial resolution data of this part of the world. Nevertheless, MIVIS deployments will touch other parts of the world, where a major interest from the international scientific community is present.

Laboratory Directed Research and Development FY2011 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Craig, W; Sketchley, J; Kotta, P

2012-03-22

A premier applied-science laboratory, Lawrence Livermore National Laboratory (LLNL) has earned the reputation as a leader in providing science and technology solutions to the most pressing national and global security problems. The LDRD Program, established by Congress at all DOE national laboratories in 1991, is LLNL's most important single resource for fostering excellent science and technology for today's needs and tomorrow's challenges. The LDRD internally directed research and development funding at LLNL enables high-risk, potentially high-payoff projects at the forefront of science and technology. The LDRD Program at Livermore serves to: (1) Support the Laboratory's missions, strategic plan, and foundationalmore » science; (2) Maintain the Laboratory's science and technology vitality; (3) Promote recruiting and retention; (4) Pursue collaborations; (5) Generate intellectual property; and (6) Strengthen the U.S. economy. Myriad LDRD projects over the years have made important contributions to every facet of the Laboratory's mission and strategic plan, including its commitment to nuclear, global, and energy and environmental security, as well as cutting-edge science and technology and engineering in high-energy-density matter, high-performance computing and simulation, materials and chemistry at the extremes, information systems, measurements and experimental science, and energy manipulation. A summary of each project was submitted by the principal investigator. Project summaries include the scope, motivation, goals, relevance to DOE/NNSA and LLNL mission areas, the technical progress achieved in FY11, and a list of publications that resulted from the research. The projects are: (1) Nuclear Threat Reduction; (2) Biosecurity; (3) High-Performance Computing and Simulation; (4) Intelligence; (5) Cybersecurity; (6) Energy Security; (7) Carbon Capture; (8) Material Properties, Theory, and Design; (9) Radiochemistry; (10) High-Energy-Density Science; (11) Laser

Sequim Marine Research Laboratory routine environmental measurements during CY-1976

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fix, J.J.; Blumer, P.J.

1977-05-01

Beginning in 1976, a routine environmental program was established at the Marine Research Laboratory (MRL) at Sequim, Washington. The program is designed, primarily, to determine levels of radioactivity present in selected biota in Sequim Bay. The biota were selected because of their presence near the laboratory and their capacity to concentrate trace elements. Other samples were obtained to determine the radionuclides in Sequim Bay and laboratory drinking water, as well as the ambient radiation exposure levels and surface deposition of fallout radionuclides for the laboratory area. A summary of the analytical methods used is included. The present document includes datamore » obtained during CY 1976, the first year of the program. Radionuclides present in samples are attributed to fallout. Data are included on content of oil and Cu in seawater samples.« less

Research and the planned Space Experiment Research and Processing Laboratory

NASA Technical Reports Server (NTRS)

2000-01-01

Original photo and caption dated August 14, 1995: 'KSC plant physiologist Dr. Gary Stutte harvests a potato grown in the Biomass Production Chamber of the Controlled environment Life Support system (CELSS) in Hangar L at Cape Canaveral Air Station. During a 418-day 'human rated' experiment, potato crops grown in the chamber provided the equivalent of a continuous supply of the oxygen for one astronaut, along with 55 percent of that long-duration space flight crew member's caloric food requirements and enough purified water for four astronauts while absorbing their expelled carbon dioxide. The experiment provided data that will help demonstarte the feasibility of the CELSS operating as a bioregenerative life support system for lunar and deep-space missions that can operate independently without the need to carry consumables such as air, water and food, while not requiring the expendable air and water system filters necessary on today's human-piloted spacecraft.' His work is an example of the type of life sciences research that will be conducted at the Space Experiment Research Procession Laboratory (SERPL). The SERPL is a planned 100,000-square-foot laboratory that will provide expanded and upgraded facilities for hosting International Space Station experiment processing. In addition, it will provide better support for other biological and life sciences payload processing at KSC. It will serve as a magnet facility for a planned 400-acre Space Station Commerce Park.

Research and the planned Space Experiment Research and Processing Laboratory

NASA Technical Reports Server (NTRS)

2000-01-01

Original photo and caption dated August 14, 1995: 'KSC plant physiologist Dr. Gary Stutte (right) and Cheryl Mackowiak harvest potatoes grown in the Biomass Production Chamber of the Controlled Enviornment Life Support System (CELSS in Hangar L at Cape Canaveral Air Station. During a 418-day 'human rated' experiment, potato crops grown in the chamber provided the equivalent of a continuous supply of the oxygen for one astronaut, along with 55 percent of that long-duration space flight crew member's caloric food requirements and enough purified water for four astronauts while absorbing their expelled carbon dioxide. The experiment provided data that will help demonstarte the feasibility of the CELSS operating as a bioregenerative life support system for lunar and deep-space missions that can operate independently without the need to carry consumables such as air, water and food, while not requiring the expendable air and water system filters necessary on today's human-piloted spacecraft.' Their work is an example of the type of life sciences research that will be conducted at the Space Experiment Research Procession Laboratory (SERPL). The SERPL is a planned 100,000-square-foot laboratory that will provide expanded and upgraded facilities for hosting International Space Station experiment processing. In addition, it will provide better support for other biological and life sciences payload processing at KSC. It will serve as a magnet facility for a planned 400-acre Space Station Commerce Park.

Space Station Freedom: a unique laboratory for gravitational biology research

NASA Technical Reports Server (NTRS)

Phillips, R. W.; Cowing, K. L.

1993-01-01

The advent of Space Station Freedom (SSF) will provide a permanent laboratory in space with unparalleled opportunities to perform biological research. As with any spacecraft there will also be limitations. It is our intent to describe this space laboratory and present a picture of how scientists will conduct research in this unique environment we call space. SSF is an international venture which will continue to serve as a model for other peaceful international efforts. It is hoped that as the human race moves out from this planet back to the moon and then on to Mars that SSF can serve as a successful example of how things can and should be done.

The role and importance of veterinary laboratories in the prevention and control of infectious diseases of animals.

PubMed

Truszczyński, M J

1998-08-01

Veterinary laboratories which deal with infectious diseases form three groups according to the tasks for which they are responsible. The first group includes central or national veterinary laboratories, national or international reference laboratories, high-security laboratories, district regional or state veterinary diagnostic laboratories. The major role of these laboratories is to assist national Veterinary Services in diagnosing infectious animal diseases. The second group comprises laboratories that produce veterinary diagnostic kits and those that produce veterinary vaccines. The third group is composed of veterinary research laboratories, which generally concentrate on basic research and do not contribute directly to the diagnosis and control of infectious animal diseases. The author describes the objectives of each of the three groups of laboratories.

Institutional training programs for research personnel conducted by laboratory-animal veterinarians.

PubMed

Dyson, Melissa C; Rush, Howard G

2012-01-01

Research institutions are required by federal law and national standards to ensure that individuals involved in animal research are appropriately trained in techniques and procedures used on animals. Meeting these requirements necessitates the support of institutional authorities; policies for the documentation and enforcement of training; resources to support and provide training programs; and high-quality, effective educational material. Because of their expertise, laboratory-animal veterinarians play an essential role in the design, implementation, and provision of educational programs for faculty, staff, and students in biomedical research. At large research institutions, provision of a training program for animal care and use personnel can be challenging because of the animal-research enterprise's size and scope. At the University of Michigan (UM), approximately 3,500 individuals have direct contact with animals used in research. We describe a comprehensive educational program for animal care and use personnel designed and provided by laboratory-animal veterinarians at UM and discuss the challenges associated with its implementation.

Lumber drying and heat sterilization research at the U.S. Forest Products Laboratory

Treesearch

William T. Simpson

2002-01-01

The Forest Products Laboratory (FPL) has a long history of research and technology transfer in lumber drying. Many of the dry kiln schedules used in industry today were developed by the staff of the Laboratory, and for many years the Laboratory conducted a kiln drying short course for training dry kiln operators. The purpose of this report is to describe the Laboratory...

New Visiting Scholars Program at Frederick National Laboratory | Office of Cancer Clinical Proteomics Research

Cancer.gov

The Frederick National Laboratory for Cancer Research is now accepting Expressions of Interest to its new Visiting Scholars Program (VSP). VSP is a unique opportunity for researchers to work on important cancer and AIDS projects with teams of scientists at the only federal national laboratory in the United States devoted exclusively to biomedical research.

2014 Fermilab Laboratory Directoed Research & Development Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

W. Wester

After initiation by the Fermilab Laboratory Director, a team from the senior Laboratory leadership and a Laboratory Directed Research and Development (LDRD) Advisory Committee developed an implementation plan for LDRD at Fermilab for the first time. This implementation was captured in the approved Fermilab 2014 LDRD Program Plan and followed directions and guidance from the Department of Energy (DOE) order, DOE O 413.2B, a “Roles, Responsibilities, and Guidelines, …” document, and examples of best practices at other DOE Office of Science Laboratories. At Fermilab, a FY14 midyear Call for Proposals was issued. A LDRD Selection Committee evaluated those proposals thatmore » were received and provided a recommendation to the Laboratory Director who approved seven LDRD projects. This Annual Report focuses on the status of those seven projects and provides an overview of the current status of LDRD at Fermilab. The seven FY14 LDRD approved projects had a date of initiation late in FY14 such that this report reflects approximately six months of effort approximately through January 2015. The progress of these seven projects, the subsequent award of six additional new projects beginning in FY15, and preparations for the issuance of the FY16 Call for Proposals indicates that LDRD is now integrated into the overall annual program at Fermilab. All indications are that LDRD is improving the scientific and technical vitality of the Laboratory and providing new, novel, or cutting edge projects carried out at the forefront of science and technology and aligned with the mission and strategic visions of Fermilab and the Department of Energy.« less

Nanotechnology Characterization Laboratory Unveils New Technical Services for Drug Developers | Frederick National Laboratory for Cancer Research

Cancer.gov

FREDERICK, Md. -- Drug developers now have access to a shared analytical technology, developed and provided by the Frederick National Laboratory for Cancer Research, that helps fine-tune nanomedicine formulations and overcomes a key hurdle on the pat

Bringing the Excitement and Motivation of Research to Students; Using Inquiry and Research-Based Learning in a Year-Long Biochemistry Laboratory: Part II--Research-Based Laboratory--A Semester-Long Research Approach Using Malate Dehydrogenase as a Research Model

ERIC Educational Resources Information Center

Knutson, Kristopher; Smith, Jennifer; Nichols, Paul; Wallert, Mark A.; Provost, Joseph J.

2010-01-01

Research-based learning in a teaching environment is an effective way to help bring the excitement and experience of independent bench research to a large number of students. The program described here is the second of a two-semester biochemistry laboratory series. Here, students are empowered to design, execute and analyze their own experiments…

SwarmSight: Measuring the Temporal Progression of Animal Group Activity Levels from Natural Scene and Laboratory Videos

PubMed Central

Birgiolas, Justas; Jernigan, Christopher M.; Smith, Brian H.; Crook, Sharon M.

2016-01-01

We describe SwarmSight (available at: https://github.com/justasb/SwarmSight), a novel, open-source, Microsoft Windows software tool for quantitative assessment of the temporal progression of animal group activity levels from recorded videos. The tool utilizes a background subtraction machine vision algorithm and provides an activity metric that can be used to quantitatively assess and compare animal group behavior. Here we demonstrate the tool utility by analyzing defensive bee behavior as modulated by alarm pheromones, wild bird feeding onset and interruption, and cockroach nest finding activity. While more sophisticated, commercial software packages are available, SwarmSight provides a low-cost, open-source, and easy-to-use alternative that is suitable for a wide range of users, including minimally trained research technicians and behavioral science undergraduate students in classroom laboratory settings. PMID:27130170

Analysis and Implementation of an Electronic Laboratory Notebook in a Biomedical Research Institute

PubMed Central

Dujardin, Gwendal; Cabrera-Andrade, Alejandro; Paz-y-Miño, César; Indacochea, Alberto; Inglés-Ferrándiz, Marta; Nadimpalli, Hima Priyanka; Collu, Nicola; Dublanche, Yann; De Mingo, Ismael; Camargo, David

2016-01-01

Electronic laboratory notebooks (ELNs) will probably replace paper laboratory notebooks (PLNs) in academic research due to their advantages in data recording, sharing and security. Despite several reports describing technical characteristics of ELNs and their advantages over PLNs, no study has directly tested ELN performance among researchers. In addition, the usage of tablet-based devices or wearable technology as ELN complements has never been explored in the field. To implement an ELN in our biomedical research institute, here we first present a technical comparison of six ELNs using 42 parameters. Based on this, we chose two ELNs, which were tested by 28 scientists for a 3-month period and by 80 students via hands-on practical exercises. Second, we provide two survey-based studies aimed to compare these two ELNs (PerkinElmer Elements and Microsoft OneNote) and to analyze the use of tablet-based devices. We finally explore the advantages of using wearable technology as ELNs tools. Among the ELNs tested, we found that OneNote presents almost all parameters evaluated (39/42) and both surveyed groups preferred OneNote as an ELN solution. In addition, 80% of the surveyed scientists reported that tablet-based devices improved the use of ELNs in different respects. We also describe the advantages of using OneNote application for Apple Watch as an ELN wearable complement. This work defines essential features of ELNs that could be used to improve ELN implementation and software development. PMID:27479083

Analysis and Implementation of an Electronic Laboratory Notebook in a Biomedical Research Institute.

PubMed

Guerrero, Santiago; Dujardin, Gwendal; Cabrera-Andrade, Alejandro; Paz-Y-Miño, César; Indacochea, Alberto; Inglés-Ferrándiz, Marta; Nadimpalli, Hima Priyanka; Collu, Nicola; Dublanche, Yann; De Mingo, Ismael; Camargo, David

2016-01-01

Electronic laboratory notebooks (ELNs) will probably replace paper laboratory notebooks (PLNs) in academic research due to their advantages in data recording, sharing and security. Despite several reports describing technical characteristics of ELNs and their advantages over PLNs, no study has directly tested ELN performance among researchers. In addition, the usage of tablet-based devices or wearable technology as ELN complements has never been explored in the field. To implement an ELN in our biomedical research institute, here we first present a technical comparison of six ELNs using 42 parameters. Based on this, we chose two ELNs, which were tested by 28 scientists for a 3-month period and by 80 students via hands-on practical exercises. Second, we provide two survey-based studies aimed to compare these two ELNs (PerkinElmer Elements and Microsoft OneNote) and to analyze the use of tablet-based devices. We finally explore the advantages of using wearable technology as ELNs tools. Among the ELNs tested, we found that OneNote presents almost all parameters evaluated (39/42) and both surveyed groups preferred OneNote as an ELN solution. In addition, 80% of the surveyed scientists reported that tablet-based devices improved the use of ELNs in different respects. We also describe the advantages of using OneNote application for Apple Watch as an ELN wearable complement. This work defines essential features of ELNs that could be used to improve ELN implementation and software development.

1996 Laboratory directed research and development annual report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meyers, C.E.; Harvey, C.L.; Lopez-Andreas, L.M.

This report summarizes progress from the Laboratory Directed Research and Development (LDRD) program during fiscal year 1996. In addition to a programmatic and financial overview, the report includes progress reports from 259 individual R&D projects in seventeen categories. The general areas of research include: engineered processes and materials; computational and information sciences; microelectronics and photonics; engineering sciences; pulsed power; advanced manufacturing technologies; biomedical engineering; energy and environmental science and technology; advanced information technologies; counterproliferation; advanced transportation; national security technology; electronics technologies; idea exploration and exploitation; production; and science at the interfaces - engineering with atoms.

Aircraft in the Flight Research Building at the Aircraft Engine Research Laboratory

NASA Image and Video Library

1944-06-21

A Consolidated B–24D Liberator (left), Boeing B–29 Superfortress (background), and Lockheed RA–29 Hudson (foreground) parked inside the Flight Research Building at the National Advisory Committee for Aeronautics (NACA) Aircraft Engine Research Laboratory in Cleveland, Ohio. A P–47G Thunderbolt and P–63A King Cobra are visible in the background. The laboratory utilized 15 different aircraft during the final 2.5 years of World War II. This starkly contrasts with the limited-quantity, but long-duration aircraft of the NASA’s modern fleet. The Flight Research Building is a 272- by 150-foot hangar with an internal height ranging from 40 feet at the sides to 90 feet at its apex. The steel support trusses were pin-connected at the top with tension members extending along the corrugated transite walls down to the floor. The 37.5-foot-tall and 250-foot-long doors on either side can be opened in sections. The hangar included a shop area and stock room along the far wall, and a single-story office wing with nine offices, behind the camera. The offices were later expanded. The hangar has been in continual use since its completion in December 1942. Nearly 70 different aircraft have been sheltered here over the years. Temporary offices were twice constructed over half of the floor area when office space was at a premium.

The impact of instructor grouping strategies on student efficacy in inquiry science labs: A phenomenological case study of grouping perceptions and strategies

NASA Astrophysics Data System (ADS)

Miller, Nathaniel J.

Abundant educational research has integrated Albert Bandura's concepts of self-efficacy and collective efficacy within educational settings. In this phenomenological case study, the investigation sought to capture the manifestation of self-efficacy and collective efficacy within inquiry-based science laboratory courses. Qualitative data was derived from student efficacy surveys, direct classroom observations, and three-tiered interviews with teacher participants. Four high school science instructors and their students from two school districts in Northern Illinois were selected to participate in the study. This study sought to identify instructor strategies or criteria used to formulate student laboratory groups and the impact of such groupings on student self-efficacy and collective efficacy. Open coding of interview transcripts, observation logs, and student surveys led to the development of eight emerging themes. These themes included the purpose of science laboratory activities, instructor grouping strategies, instructor roles, instructor's perceptions, science laboratory assessment, student interactions, learner self-perceptions, and grouping preferences. Results from the study suggest that some students were innately inclined to assume leadership roles, smaller groupings had greater participation from all group members, students had a strong preference for working collaboratively in groups, and students desired to maintain stable laboratory groups in lieu of periodically changing laboratory partners. As with all case study methodologies, the findings of the study were limited to the individual participants at research sites and were not generalizable to all science classrooms. Additional research in the realms of group size, group autonomy, and student interviews would provide even greater insights into the observed phenomena.

Found in translation: Integrating laboratory and clinical oncology research

PubMed Central

Wagner, H

2008-01-01

Translational research in medicine aims to inform the clinic and the laboratory with the results of each other’s work, and to bring promising and validated new therapies into clinical application. While laudable in intent, this is complicated in practice and the current state of translational research in cancer shows both striking success stories and examples of the numerous potential obstacles as well as opportunities for delays and errors in translation. This paper reviews the premises, promises, and problems of translational research with a focus on radiation oncology and suggests opportunities for improvements in future research design. PMID:21611010

Students' Knowledge Construction in Small Groups in the Seventh Grade Biology Laboratory: Verbal Communication and Physical Engagement.

ERIC Educational Resources Information Center

She, Hsiao-Ching

1999-01-01

Reports on a study of seventh-grade students' interactions in small groups during a biology laboratory activity. Finds that girls have the potential to perform equally as well as do boys in the science laboratory and that both individual and gender differences contribute to students' differential verbal communication and laboratory engagement.…

Field Research Studying Whales in an Undergraduate Animal Behavior Laboratory

ERIC Educational Resources Information Center

MacLaren, R. David; Schulte, Dianna; Kennedy, Jen

2012-01-01

This work describes a new field research laboratory in an undergraduate animal behavior course involving the study of whale behavior, ecology and conservation in partnership with a non-profit research organization--the Blue Ocean Society for Marine Conservation (BOS). The project involves two weeks of training and five weekend trips on whale watch…

Remote Sensing Information Sciences Research Group: Santa Barbara Information Sciences Research Group, year 4

NASA Technical Reports Server (NTRS)

Estes, John E.; Smith, Terence; Star, Jeffrey L.

1987-01-01

Information Sciences Research Group (ISRG) research continues to focus on improving the type, quantity, and quality of information which can be derived from remotely sensed data. Particular focus in on the needs of the remote sensing research and application science community which will be served by the Earth Observing System (EOS) and Space Station, including associated polar and co-orbiting platforms. The areas of georeferenced information systems, machine assisted information extraction from image data, artificial intelligence and both natural and cultural vegetation analysis and modeling research will be expanded.

Groups That Work: Student Achievement in Group Research Projects and Effects on Individual Learning

ERIC Educational Resources Information Center

Monson, Renee

2017-01-01

Group research projects frequently are used to teach undergraduate research methods. This study uses multivariate analyses to examine the characteristics of higher-achieving groups (those that earn higher grades on group research projects) and to estimate the effects of participating in higher-achieving groups on subsequent individual learning…

Laboratory for Energy-Related Health Research annual report, fiscal year 1986

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abell, D.L.

1989-02-01

This report to the US Department of Energy summarizes research activities for the period from 1 October 1985--30 September 1986 at the Laboratory for Energy-related Health Research (LEHR) which is operated by the University of California, Davis. The laboratory's research objective is to provide new knowledge for an improved understanding of the potential bioenvironmental and occupational health problems associated with energy utilization to contribute to the safe and healthful development of energy resources for the benefit of mankind. This research encompasses several areas of basic investigation that relate to toxicological and biomedical problems associated with potentially toxic chemical and radioactivemore » substances and ionizing radiation, with particular emphasis on carcinogenicity. Studies of systemic injury and nuclear medical diagnostic and therapeutic methods are also involved. This is an interdisciplinary program spanning physics, chemistry, environmental engineering, biophysics and biochemistry, cellular and molecular biology, physiology, immunology, toxicology, both human and veterinary medicine, nuclear medicine, pathology, hematology, radiation biology, reproductive biology, oncology, biomathematics, and computer science. The principal themes of the research at LEHR center around the biology, radiobiology, and health status of the skeleton and its blood-forming constituents; the toxicology and properties of airborne materials; the beagle as an experimental animal model; carcinogenesis; and the scaling of the results from laboratory animal studies to man for appropriate assessment of risk.« less

United States Air Force Summer Research Program -- 1993. Volume 16. Arnold Engineering Development Center. Frank J. Seiler Research Laboratory. Wilford Hall Medical Center

DTIC Science & Technology

1993-12-01

A I 7f t UNITED STATE AIR FORCE SUMMER RESEARCH PROGRAM -- 1993 SUMMER RESEARCH PROGRAM FINAL REPORTS VOLUME 16 ARNOLD ENGINEERING DEVELOPMENT CENTER...FRANK J. SELLER RESEARCH LABORATORY WILFORD HALL MEDICAL CENTER RESEARCH & DEVELOPMENT LABORATORIES 5800 Uplander Way Culver City, CA 90230-6608...National Rd. Vol-Page No: 15-44 Dist Tecumseh High School 8.4 New Carlisle, OH 45344-0000 Barber, Jason Laboratory: AL/CF 1000 10th St. Vol-Page No

Hood College, Frederick National Laboratory Will Renew Popular Scientific Symposium | Frederick National Laboratory for Cancer Research

Cancer.gov

FREDERICK, Md. -- Hood College and the Frederick National Laboratory for Cancer Research have partnered to cohost an annual scientific symposium in the tradition of the landmark Oncogene Meeting, a national fixture in Frederick for more than 20 year

Using Human Inquiry Groups in Counselling Research.

ERIC Educational Resources Information Center

West, William

1996-01-01

Explores the nature of human inquiry groups and how such groups decide on a research agenda. Outlines the stages involved in the process and considers the value of human inquiry as a qualitative methodology for counseling research. Compares the roles of the human inquiry researcher and the counselor. (RJM)

Defining a roadmap for harmonizing quality indicators in Laboratory Medicine: a consensus statement on behalf of the IFCC Working Group "Laboratory Error and Patient Safety" and EFLM Task and Finish Group "Performance specifications for the extra-analytical phases".

PubMed

Sciacovelli, Laura; Panteghini, Mauro; Lippi, Giuseppe; Sumarac, Zorica; Cadamuro, Janne; Galoro, César Alex De Olivera; Pino Castro, Isabel Garcia Del; Shcolnik, Wilson; Plebani, Mario

2017-08-28

The improving quality of laboratory testing requires a deep understanding of the many vulnerable steps involved in the total examination process (TEP), along with the identification of a hierarchy of risks and challenges that need to be addressed. From this perspective, the Working Group "Laboratory Errors and Patient Safety" (WG-LEPS) of International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) is focusing its activity on implementation of an efficient tool for obtaining meaningful information on the risk of errors developing throughout the TEP, and for establishing reliable information about error frequencies and their distribution. More recently, the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) has created the Task and Finish Group "Performance specifications for the extra-analytical phases" (TFG-PSEP) for defining performance specifications for extra-analytical phases. Both the IFCC and EFLM groups are working to provide laboratories with a system to evaluate their performances and recognize the critical aspects where improvement actions are needed. A Consensus Conference was organized in Padova, Italy, in 2016 in order to bring together all the experts and interested parties to achieve a consensus for effective harmonization of quality indicators (QIs). A general agreement was achieved and the main outcomes have been the release of a new version of model of quality indicators (MQI), the approval of a criterion for establishing performance specifications and the definition of the type of information that should be provided within the report to the clinical laboratories participating to the QIs project.

Frederick National Laboratory Rallies to Meet Demand for Zika Vaccine | Frederick National Laboratory for Cancer Research

Cancer.gov

The Frederick National Laboratory for Cancer Research is producing another round of Zika vaccine for ongoing studies to determine the best delivery method and dosage. This will lay the groundwork for additional tests to see if the vaccine prevents i

Georgia Teachers in Academic Laboratories: Research Experiences in the Geosciences

NASA Astrophysics Data System (ADS)

Barrett, D.

2005-12-01

The Georgia Intern-Fellowships for Teachers (GIFT) is a collaborative effort designed to enhance mathematics and science experiences of Georgia teachers and their students through summer research internships for teachers. By offering business, industry, public science institute and research summer fellowships to teachers, GIFT provides educators with first-hand exposure to the skills and knowledge necessary for the preparation of our future workforce. Since 1991, GIFT has placed middle and high school mathematics, science and technology teachers in over 1000 positions throughout the state. In these fellowships, teachers are involved in cutting edge scientific and engineering research, data analysis, curriculum development and real-world inquiry and problem solving, and create Action Plans to assist them in translating the experience into changed classroom practice. Since 2004, an increasing number of high school students have worked with their teachers in research laboratories. The GIFT program places an average of 75 teachers per summer into internship positions. In the summer of 2005, 83 teachers worked in corporate and research environments throughout the state of Georgia and six of these positions involved authentic research in geoscience related departments at the Georgia Institute of Technology, including aerospace engineering and the earth and atmospheric sciences laboratories. This presentation will review the history and the structure of the program including the support system for teachers and mentors as well as the emphasis on inquiry based learning strategies. The focus of the presentation will be a comparison of two placement models of the teachers placed in geoscience research laboratories: middle school earth science teachers placed in a 6 week research experience and high school teachers placed in 7 week internships with teams of 3 high school students. The presentation will include interviews with faculty to determine the value of these experiences

Laboratory Directed Research and Development Program FY 2008 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

editor, Todd C Hansen

2009-02-23

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operatemore » unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Berkeley Lab's research and the Laboratory Directed Research and Development (LDRD) program support DOE's Strategic Themes that are codified in DOE's 2006 Strategic Plan (DOE/CF-0010), with a primary focus on Scientific Discovery and Innovation. For that strategic theme, the Fiscal Year (FY) 2008 LDRD projects support each one of the three goals through multiple strategies described in the plan. In addition, LDRD efforts support the four goals of Energy Security, the two goals of Environmental Responsibility, and Nuclear Security (unclassified fundamental research that supports stockpile safety and nonproliferation programs). The LDRD program supports Office of Science strategic plans, including the 20-year Scientific Facilities Plan and the Office of Science Strategic Plan. The research also supports the strategic directions periodically under consideration and

First International Conference on Laboratory Research for Planetary Atmospheres

NASA Technical Reports Server (NTRS)

Fox, Kenneth (Editor); Allen, John E., Jr. (Editor); Stief, Louis J. (Editor); Quillen, Diana T. (Editor)

1990-01-01

Proceedings of the First International Conference on Laboratory Research for Planetary Atmospheres are presented. The covered areas of research include: photon spectroscopy, chemical kinetics, thermodynamics, and charged particle interactions. This report contains the 12 invited papers, 27 contributed poster papers, and 5 plenary review papers presented at the conference. A list of attendees and a reprint of the Report of the Subgroup on Strategies for Planetary Atmospheres Exploration (SPASE) are provided in two appendices.

THE EPA NATIONAL EXPOSURE RESEARCH LABORATORY CHILDREN'S PESTICIDE EXPOSURE MEASUREMENT PROGRAM

EPA Science Inventory

The U.S. EPA's National Exposure Research Laboratory (NERL) conducts research in support of the Food Quality Protection Act (FQPA) of 1996. FQPA requires that children's risks to pesticide exposures be considered during the tolerance-setting process. The Act requires exposure...

THE EPA NATIONAL EXPOSURE RESEARCH LABORATORY CHILDREN'S PESTICIDE EXPOSURE MEASUREMENT PROGRAM

EPA Science Inventory

The U.S. Environmental Protection Agency (EPA) National Exposure Research Laboratory (NERL) is performing research in support of the Food Quality Protection Act (FQPA) of 1996. This act requires that pesticide exposure assessments to be conducted for all potential sources, rou...

41 CFR 109-25.109 - Laboratory and research equipment.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Laboratory and research equipment. 109-25.109 Section 109-25.109 Public Contracts and Property Management Federal Property Management Regulations System (Continued) DEPARTMENT OF ENERGY PROPERTY MANAGEMENT REGULATIONS SUPPLY AND...

THE NATIONAL EXPOSURE RESEARCH LABORATORY'S COMPREHENSIVE HUMAN ACTIVITY DATABASE

EPA Science Inventory

EPA's National Exposure Research Laboratory (NERL) has combined data from nine U.S. studies related to human activities into one comprehensive data system that can be accessed via the world-wide web. The data system is called CHAD-Consolidated Human Activity Database-and it is ...

THE NATIONAL EXPOSURE RESEARCH LABORATORY'S CONSOLIDATED HUMAN ACTIVITY DATABASE

EPA Science Inventory

EPA's National Exposure Research Laboratory (NERL) has combined data from 12 U.S. studies related to human activities into one comprehensive data system that can be accessed via the Internet. The data system is called the Consolidated Human Activity Database (CHAD), and it is ...

Wiki Laboratory Notebooks: Supporting Student Learning in Collaborative Inquiry-Based Laboratory Experiments

NASA Astrophysics Data System (ADS)

Lawrie, Gwendolyn Angela; Grøndahl, Lisbeth; Boman, Simon; Andrews, Trish

2016-06-01

Recent examples of high-impact teaching practices in the undergraduate chemistry laboratory that include course-based undergraduate research experiences and inquiry-based experiments require new approaches to assessing individual student learning outcomes. Instructors require tools and strategies that can provide them with insight into individual student contributions to collaborative group/teamwork throughout the processes of experimental design, data analysis, display and communication of their outcomes in relation to their research question(s). Traditional assessments in the form of laboratory notebooks or experimental reports provide limited insight into the processes of collaborative inquiry-based activities. A wiki environment offers a collaborative domain that can potentially support collaborative laboratory processes and scientific record keeping. In this study, the effectiveness of the wiki in supporting laboratory learning and assessment has been evaluated through analysis of the content and histories for three consenting, participating groups of students. The conversational framework has been applied to map the relationships between the instructor, tutor, students and laboratory activities. Analytics that have been applied to the wiki platform include: character counts, page views, edits, timelines and the extent and nature of the contribution by each student to the wiki. Student perceptions of both the role and the impact of the wiki on their experiences and processes have also been collected. Evidence has emerged from this study that the wiki environment has enhanced co-construction of understanding of both the experimental process and subsequent communication of outcomes and data. A number of features are identified to support success in the use of the wiki platform for laboratory notebooks.

A survey on faculty perspectives on the transition to a biochemistry course-based undergraduate research experience laboratory.

PubMed

Craig, Paul A

2017-09-01

It will always remain a goal of an undergraduate biochemistry laboratory course to engage students hands-on in a wide range of biochemistry laboratory experiences. In 2006, our research group initiated a project for in silico prediction of enzyme function based only on the 3D coordinates of the more than 3800 proteins "of unknown function" in the Protein Data Bank, many of which resulted from the Protein Structure Initiative. Students have used the ProMOL plugin to the PyMOL molecular graphics environment along with BLAST, Pfam, and Dali to predict protein functions. As young scientists, these undergraduate research students wanted to see if their predictions were correct and so they developed an approach for in vitro testing of predicted enzyme function that included literature exploration, selection of a suitable assay and the search for commercially available substrates. Over the past two years, a team of faculty members from seven different campuses (California Polytechnic San Luis Obispo, Hope College, Oral Roberts University, Rochester Institute of Technology, St. Mary's University, Ursinus College, and Purdue University) have transferred this approach to the undergraduate biochemistry teaching laboratory as a Course-based Undergraduate Research Experience. A series of ten course modules and eight instructional videos have been created (www.promol.org/home/basil-modules-1) and the group is now expanding these resources, creating assessments and evaluating how this approach helps student to grow as scientists. The focus of this manuscript will be the logistical implications of this transition on campuses that have different cultures, expectations, schedules, and student populations. © 2017 by The International Union of Biochemistry and Molecular Biology, 45(5):426-436, 2017. © 2017 The International Union of Biochemistry and Molecular Biology.

Eagleworks Laboratories: Advanced Propulsion Physics Research

NASA Technical Reports Server (NTRS)

White, Harold; March, Paul; Williams, Nehemiah; ONeill, William

2011-01-01

NASA/JSC is implementing an advanced propulsion physics laboratory, informally known as "Eagleworks", to pursue propulsion technologies necessary to enable human exploration of the solar system over the next 50 years, and enabling interstellar spaceflight by the end of the century. This work directly supports the "Breakthrough Propulsion" objectives detailed in the NASA OCT TA02 In-space Propulsion Roadmap, and aligns with the #10 Top Technical Challenge identified in the report. Since the work being pursued by this laboratory is applied scientific research in the areas of the quantum vacuum, gravitation, nature of space-time, and other fundamental physical phenomenon, high fidelity testing facilities are needed. The lab will first implement a low-thrust torsion pendulum (<1 uN), and commission the facility with an existing Quantum Vacuum Plasma Thruster. To date, the QVPT line of research has produced data suggesting very high specific impulse coupled with high specific force. If the physics and engineering models can be explored and understood in the lab to allow scaling to power levels pertinent for human spaceflight, 400kW SEP human missions to Mars may become a possibility, and at power levels of 2MW, 1-year transit to Neptune may also be possible. Additionally, the lab is implementing a warp field interferometer that will be able to measure spacetime disturbances down to 150nm. Recent work published by White [1] [2] [3] suggests that it may be possible to engineer spacetime creating conditions similar to what drives the expansion of the cosmos. Although the expected magnitude of the effect would be tiny, it may be a "Chicago pile" moment for this area of physics.

Impacts: NIST Building and Fire Research Laboratory (technical and societal)

NASA Astrophysics Data System (ADS)

Raufaste, N. J.

1993-08-01

The Building and Fire Research Laboratory (BFRL) of the National Institute of Standards and Technology (NIST) is dedicated to the life cycle quality of constructed facilities. The report describes major effects of BFRL's program on building and fire research. Contents of the document include: structural reliability; nondestructive testing of concrete; structural failure investigations; seismic design and construction standards; rehabilitation codes and standards; alternative refrigerants research; HVAC simulation models; thermal insulation; residential equipment energy efficiency; residential plumbing standards; computer image evaluation of building materials; corrosion-protection for reinforcing steel; prediction of the service lives of building materials; quality of construction materials laboratory testing; roofing standards; simulating fires with computers; fire safety evaluation system; fire investigations; soot formation and evolution; cone calorimeter development; smoke detector standards; standard for the flammability of children's sleepwear; smoldering insulation fires; wood heating safety research; in-place testing of concrete; communication protocols for building automation and control systems; computer simulation of the properties of concrete and other porous materials; cigarette-induced furniture fires; carbon monoxide formation in enclosure fires; halon alternative fire extinguishing agents; turbulent mixing research; materials fire research; furniture flammability testing; standard for the cigarette ignition resistance of mattresses; support of navy firefighter trainer program; and using fire to clean up oil spills.

Nuclear decay data files of the Dosimetry Research Group

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eckerman, K.F.; Westfall, R.J.; Ryman, J.C.

1993-12-01

This report documents the nuclear decay data files used by the Dosimetry Research Group at Oak Ridge National Laboratory and the utility DEXRAX which provides access to the files. The files are accessed, by nuclide, to extract information on the intensities and energies of the radiations associated with spontaneous nuclear transformation of the radionuclides. In addition, beta spectral data are available for all beta-emitting nuclides. Two collections of nuclear decay data are discussed. The larger collection contains data for 838 radionuclides, which includes the 825 radionuclides assembled during the preparation of Publications 30 and 38 of the International Commission onmore » Radiological Protection (ICRP) and 13 additional nuclides evaluated in preparing a monograph for the Medical Internal Radiation Dose (MIRD) Committee of the Society of Nuclear Medicine. The second collection is composed of data from the MIRD monograph and contains information for 242 radionuclides. Abridged tabulations of these data have been published by the ICRP in Publication 38 and by the Society of Nuclear Medicine in a monograph entitled ``MIRD: Radionuclide Data and Decay Schemes.`` The beta spectral data reported here have not been published by either organization. Electronic copies of the files and the utility, along with this report, are available from the Radiation Shielding Information Center at Oak Ridge National Laboratory.« less

Natural Pathogens of Laboratory Mice, Rats, and Rabbits and Their Effects on Research

PubMed Central

Baker, David G.

1998-01-01

Laboratory mice, rats, and rabbits may harbor a variety of viral, bacterial, parasitic, and fungal agents. Frequently, these organisms cause no overt signs of disease. However, many of the natural pathogens of these laboratory animals may alter host physiology, rendering the host unsuitable for many experimental uses. While the number and prevalence of these pathogens have declined considerably, many still turn up in laboratory animals and represent unwanted variables in research. Investigators using mice, rats, and rabbits in biomedical experimentation should be aware of the profound effects that many of these agents can have on research. PMID:9564563

Modeling of Army Research Laboratory EMP simulators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miletta, J.R.; Chase, R.J.; Luu, B.B.

1993-12-01

Models are required that permit the estimation of emitted field signatures from EMP simulators to design the simulator antenna structure, to establish the usable test volumes, and to estimate human exposure risk. This paper presents the capabilities and limitations of a variety of EMP simulator models useful to the Army's EMP survivability programs. Comparisons among frequency and time-domain models are provided for two powerful US Army Research Laboratory EMP simulators: AESOP (Army EMP Simulator Operations) and VEMPS II (Vertical EMP Simulator II).

Group functioning of a collaborative family research team.

PubMed

Johnson, S K; Halm, M A; Titler, M G; Craft, M; Kleiber, C; Montgomery, L A; Nicholson, A; Buckwalter, K; Cram, E

1993-07-01

Collaborative research teams are an attractive means of conducting nursing research in the clinical setting because of the many opportunities that collaboration can supply. These opportunities include a chance to: (1) network with other nurses who have similar interests, (2) share knowledge and expertise for designing clinical studies that directly affect daily practice, (3) develop instruments, (4) write grant proposals, (5) collect and analyze data, and (6) prepare manuscripts for publication. The effectiveness of research teams, however, is strongly influenced by group functioning. This article describes the functioning of a collaborative family interventions research team of nursing faculty members and CNSs at a large Midwestern university setting. The formation of the group and membership characteristics are described, along with strategies used to identify the research focus and individual and group goals. Aspects related to the influence of the group on members and the internal operations of the group are also addressed. Future strategies to be explored will focus on the size of the group and joint authorship issues. The authors also set forth a number of recommendations for development of collaborative research groups.

From the Research Laboratory to the Operating Company: How Information Travels.

ERIC Educational Resources Information Center

Coppin, Ann S.; Palmer, Linda L.

1980-01-01

Reviews transmission processes of Chevron Oil Field Research Company (COFRC) research results from laboratories to end-user operating companies worldwide. Information dissemination methods described included informal communication, intercompany meetings, visits by COFRC personnel to operating company offices, distribution of written reports,…

A Place for Materials Science: Laboratory Buildings and Interdisciplinary Research at the University of Pennsylvania

ERIC Educational Resources Information Center

Choi, Hyungsub; Shields, Brit

2015-01-01

The Laboratory for Research on the Structure of Matter (LRSM), University of Pennsylvania, was built in 1965 as part of the Advanced Research Projects Agency's (ARPA) Interdisciplinary Laboratories (IDL) program intended to foster interdisciplinary research and training in materials science. The process that led to the construction of the…

USDA-ARS Knipling-Bushland U.S. Livestock Insects Research Laboratory Tick & Biting Fly Research Unit scientific update

USDA-ARS?s Scientific Manuscript database

Ticks and biting flies cause tremendous economic damage to the U.S. livestock industry while also being a health concern to humans. Research on their biology and control is done at the Knipling-Bushland U.S. Livestock Insects Research Laboratory, Tick and Biting Fly Research Unit with scientists loc...

Location for the planned Space Experiment Research and Processing Laboratory

NASA Technical Reports Server (NTRS)

2000-01-01

This diagram shows the planned locations of the Space Experiment Research and Processing Laboratory (SERPL) and the Space Station Commerce Park at Kennedy Space Center. The SERPL is a planned 100,000-square-foot laboratory that will provide expanded and upgraded facilities for hosting International Space Station experiment processing. In addition, it will provide better support for other biological and life sciences payload processing at KSC. It will serve as a magnet facility for the planned 400- acre commerce park.

Engineering Design and Automation in the Applied Engineering Technologies (AET) Group at Los Alamos National Laboratory.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wantuck, P. J.; Hollen, R. M.

2002-01-01

This paper provides an overview of some design and automation-related projects ongoing within the Applied Engineering Technologies (AET) Group at Los Alamos National Laboratory. AET uses a diverse set of technical capabilities to develop and apply processes and technologies to applications for a variety of customers both internal and external to the Laboratory. The Advanced Recovery and Integrated Extraction System (ARIES) represents a new paradigm for the processing of nuclear material from retired weapon systems in an environment that seeks to minimize the radiation dose to workers. To achieve this goal, ARIES relies upon automation-based features to handle and processmore » the nuclear material. Our Chemical Process Development Team specializes in fuzzy logic and intelligent control systems. Neural network technology has been utilized in some advanced control systems developed by team members. Genetic algorithms and neural networks have often been applied for data analysis. Enterprise modeling, or discrete event simulation, as well as chemical process simulation has been employed for chemical process plant design. Fuel cell research and development has historically been an active effort within the AET organization. Under the principal sponsorship of the Department of Energy, the Fuel Cell Team is now focusing on technologies required to produce fuel cell compatible feed gas from reformation of a variety of conventional fuels (e.g., gasoline, natural gas), principally for automotive applications. This effort involves chemical reactor design and analysis, process modeling, catalyst analysis, as well as full scale system characterization and testing. The group's Automation and Robotics team has at its foundation many years of experience delivering automated and robotic systems for nuclear, analytical chemistry, and bioengineering applications. As an integrator of commercial systems and a developer of unique custom-made systems, the team currently supports the

Behavioral Economic Laboratory Research in Tobacco Regulatory Science.

PubMed

Tidey, Jennifer W; Cassidy, Rachel N; Miller, Mollie E; Smith, Tracy T

2016-10-01

Research that can provide a scientific foundation for the United States Food and Drug Administration (FDA) tobacco policy decisions is needed to inform tobacco regulatory policy. One factor that affects the impact of a tobacco product on public health is its intensity of use, which is determined, in part, by its abuse liability or reinforcing efficacy. Behavioral economic tasks have considerable utility for assessing the reinforcing efficacy of current and emerging tobacco products. This paper provides a narrative review of several behavioral economic laboratory tasks and identifies important applications to tobacco regulatory science. Behavioral economic laboratory assessments, including operant self-administration, choice tasks and purchase tasks, can be used generate behavioral economic data on the effect of price and other constraints on tobacco product consumption. These tasks could provide an expedited simulation of the effects of various tobacco control policies across populations of interest to the FDA. Tobacco regulatory research questions that can be addressed with behavioral economic tasks include assessments of the impact of product characteristics on product demand, assessments of the abuse liability of novel and potential modified risk tobacco products (MRTPs), and assessments of the impact of conventional and novel products in vulnerable populations.

Xerox' Canadian Research Facility: The Multinational and the "Offshore" Laboratory.

ERIC Educational Resources Information Center

Marchessault, R. H.; Myers, M. B.

1986-01-01

The history, logistics, and strategy behind the Xerox Corporation's Canadian research laboratory, a subsidiary firm located outside the United States for reasons of manpower, tax incentives, and quality of life, are described. (MSE)

Technical Service Agreement (TSA) | Frederick National Laboratory for Cancer Research

Cancer.gov

Frederick National Laboratory for Cancer Research (FNLCR) scientists provide services and solutions to collaborators through the Technical Services Program, whose portfolio includes more than 200 collaborations with more than 80 partners. The Frederi

Developing Therapies for Brain Tumors: The Impact of the Johns Hopkins Hunterian Neurosurgical Research Laboratory.

PubMed

Brem, Henry; Sankey, Eric W; Liu, Ann; Mangraviti, Antonella; Tyler, Betty M

2017-01-01

The Johns Hopkins Hunterian Neurosurgical Laboratory at the Johns Hopkins University School of Medicine was created in 1904 by Harvey Cushing and William Halsted and has had a long history of fostering surgical training, encouraging basis science research, and facilitating translational application. Over the past 30 years, the laboratory has addressed the paucity of brain tumor therapies. Pre-clinical work from the laboratory led to the development of carmustine wafers with initial US Food and Drug Administration (FDA) approval in 1996. Combining carmustine wafers, radiation, and temozolomide led to a significant increase in the median survival of patients with glioblastoma. The laboratory has also developed microchips and immunotherapy to further extend survival in this heretofore underserved population. These achievements were made possible by the dedication, commitment, and creativity of more than 300 trainees of the Hunterian Neurosurgical Laboratory. The laboratory demonstrates the beneficial influence of research experience as well its substantial impact on the field of biomedical research.

Factors Affecting the Vocational Calling of Laboratory Animal Care and Research Employees

PubMed Central

Boivin, Gregory P; Markert, Ronald J

2016-01-01

We surveyed laboratory animal care and research workers to determine the factors affecting their vocational calling. The survey comprised 56 questions in 4 groups: passion, job stability or happiness, work volition, and demographics. We hypothesized that personnel who worked in the field a longer time, were older, had higher education levels, were involved with AALAS, and in higher positions in their organization were more likely to indicate a calling to the laboratory animal care field. In addition, we hypothesized that job satisfaction and classifying one's job as a calling were positively related to organizational support and work volition. Overall, 44% of respondents categorized their work as at least partially a calling. Those working at a higher level in the position of laboratory animal technician and in the organization were more likely to view their work as a calling. Increasing education level was related to work being a calling. Overall, vocational calling was significantly associated with higher pay, but technicians were the only subgroup where calling and higher pay were significantly related. Vocational calling and job satisfaction were associated with organizational support. For our sample of workers in the animal care field, other factors analyzed were not related to work being considered a calling. Leaders in the field of animal care may find our survey results valuable as they strive to adapt their organization's structure to the perceptions of their workforce with regard to their sense of calling. PMID:27931315

Four Argonne National Laboratory scientists receive Early Career Research

Science.gov Websites

Media Contacts Social Media Photos Videos Fact Sheets, Brochures and Reports Summer Science Writing Writing Internship Four Argonne National Laboratory scientists receive Early Career Research Program economic impact of cascading shortages. He will also seek to enable scaling on high-performance computing

POLLUTION PREVENTION FOR CLEANER AIR: EPA'S AIR AND ENERGY ENGINEERING RESEARCH LABORATORY

EPA Science Inventory

The article discusses the role of EPA's Air and Energy Engineering Research Laboratory (AEERL) in pollution prevention research for cleaner air. For more than 20 years, AEERL has been conducting research to identify control approaches for the pollutants and sources which contribu...

Implementation research: a mentoring programme to improve laboratory quality in Cambodia

PubMed Central

Voeurng, Vireak; Sek, Sophat; Song, Sophanna; Vong, Nora; Tous, Chansamrach; Flandin, Jean-Frederic; Confer, Deborah; Costa, Alexandre; Martin, Robert

2016-01-01

Abstract Objective To implement a mentored laboratory quality stepwise implementation (LQSI) programme to strengthen the quality and capacity of Cambodian hospital laboratories. Methods We recruited four laboratory technicians to be mentors and trained them in mentoring skills, laboratory quality management practices and international standard organization (ISO) 15189 requirements for medical laboratories. Separately, we trained staff from 12 referral hospital laboratories in laboratory quality management systems followed by tri-weekly in-person mentoring on quality management systems implementation using the LQSI tool, which is aligned with the ISO 15189 standard. The tool was adapted from a web-based resource into a software-based spreadsheet checklist, which includes a detailed action plan and can be used to qualitatively monitor each laboratory’s progress. The tool – translated into Khmer – included a set of quality improvement activities grouped into four phases for implementation with increasing complexity. Project staff reviewed the laboratories’ progress and challenges in weekly conference calls and bi-monthly meetings with focal points of the health ministry, participating laboratories and local partners. We present the achievements in implementation from September 2014 to March 2016. Findings As of March 2016, the 12 laboratories have completed 74–90% of the 104 activities in phase 1, 53–78% of the 178 activities in phase 2, and 18–26% of the 129 activities in phase 3. Conclusion Regular on-site mentoring of laboratories using a detailed action plan in the local language allows staff to learn concepts of quality management system and learn on the job without disruption to laboratory service provision. PMID:27843164

Reliability and validity of job content questionnaire for university research laboratory staff in Malaysia.

PubMed

Nehzat, F; Huda, B Z; Tajuddin, S H Syed

2014-03-01

Job Content Questionnaire (JCQ) has been proven a reliable and valid instrument to assess job stress in many countries and among various occupations. In Malaysia, both English and Malay versions of the JCQ have been administered to automotive workers, schoolteachers, and office workers. This study assessed the reliability and validity of the instrument with research laboratory staff in a university. A cross sectional study was conducted among 258 research laboratory staff in Universiti Putra Malaysia (UPM). Malaysian laboratory staff who have worked for at least one year were randomly selected from nine faculties and institutes in the university that have research laboratory. A self-administered English and Malay version of Job Content Questionnaire (JCQ) was used. Three major scales of JCQ: decision latitude, psychological job demands, and social support were assessed. Cronbach's alpha coefficients of two scales were acceptable, decision latitude and psychological job demands (0.70 and 0.72, respectively), while Cronbach's alpha coefficient for social support (0.86) was good. Exploratory factor analysis showed five factors that correspond closely to the theoretical construct of the questionnaire. The results of this research suggest that the JCQ is reliable and valid for examining psychosocial work situations and job strain among research laboratory staff. Further studies should be done for confirmative results, and further evaluation is needed on the decision authority subscale for this occupation.

An Improved Dielectric Constant Cell for Use in Student and Research Laboratories.

ERIC Educational Resources Information Center

Thompson, H. Bradford.; Walmsley, Judith A.

1979-01-01

Describes the latest stage in the design of an economical dielectric constant cell, tested in both instructional and research applications, that is suitable for student laboratories and for precision research measurements. (BT)

Revitalizing chemistry laboratory instruction

NASA Astrophysics Data System (ADS)

McBride, Phil Blake

This dissertation involves research in three major domains of chemical education as partial fulfillment of the requirements for the Ph.D. program in chemistry at Miami University with a major emphasis on chemical education, and concurrent study in organic chemistry. Unit I, Development and Assessment of a Column Chromatography Laboratory Activity, addresses the domain of Instructional Materials Development and Testing. This unit outlines the process of developing a publishable laboratory activity, testing and revising that activity, and subsequently sharing that activity with the chemical education community. A laboratory activity focusing on the separation of methylene blue and sodium fluorescein was developed to demonstrate the effects of both the stationary and mobile phase in conducting a separation. Unit II, Bringing Industry to the Laboratory, addresses the domain of Curriculum Development and Testing. This unit outlines the development of the Chemistry of Copper Mining module, which is intended for use in high school or undergraduate college chemistry. The module uses the learning cycle approach to present the chemistry of the industrial processes of mining copper to the students. The module includes thirteen investigations (three of which are web-based and ten which are laboratory experiments) and an accompanying interactive CD-ROM, which provides an explanation of the chemistry used in copper mining with a virtual tour of an operational copper mine. Unit III, An Alternative Method of Teaching Chemistry. Integrating Lecture and the Laboratory, is a project that addresses the domain of Research in Student Learning. Fundamental Chemistry was taught at Eastern Arizona College as an integrated lecture/laboratory course that met in two-hour blocks on Monday, Wednesday, and Friday. The students taking this integrated course were compared with students taking the traditional 1-hour lectures held on Monday, Wednesday, and Friday, with accompanying 3-hour lab on

National Melon Research Group

USDA-ARS?s Scientific Manuscript database

The National Melon Research Group met with the Cucurbitaceae 2010 conference in Charleston, South Carolina at 7:00 P.M. on November 17. The discussion was focused solely on cucurbit powdery mildew (CPM). Several reported increased problem with CPM or apparent changes in race. Ales Lebeda (Palacký Un...

Hairy Root as a Model System for Undergraduate Laboratory Curriculum and Research

ERIC Educational Resources Information Center

Keyes, Carol A.; Subramanian, Senthil; Yu, Oliver

2009-01-01

Hairy root transformation has been widely adapted in plant laboratories to rapidly generate transgenic roots for biochemical and molecular analysis. We present hairy root transformations as a versatile and adaptable model system for a wide variety of undergraduate laboratory courses and research. This technique is easy, efficient, and fast making…

Publication Bias in Laboratory Animal Research: A Survey on Magnitude, Drivers, Consequences and Potential Solutions

PubMed Central

ter Riet, Gerben; Korevaar, Daniel A.; Leenaars, Marlies; Sterk, Peter J.; Van Noorden, Cornelis J. F.; Bouter, Lex M.; Lutter, René; Elferink, Ronald P. Oude; Hooft, Lotty

2012-01-01

Context Publication bias jeopardizes evidence-based medicine, mainly through biased literature syntheses. Publication bias may also affect laboratory animal research, but evidence is scarce. Objectives To assess the opinion of laboratory animal researchers on the magnitude, drivers, consequences and potential solutions for publication bias. And to explore the impact of size of the animals used, seniority of the respondent, working in a for-profit organization and type of research (fundamental, pre-clinical, or both) on those opinions. Design Internet-based survey. Setting All animal laboratories in The Netherlands. Participants Laboratory animal researchers. Main Outcome Measure(s) Median (interquartile ranges) strengths of beliefs on 5 and 10-point scales (1: totally unimportant to 5 or 10: extremely important). Results Overall, 454 researchers participated. They considered publication bias a problem in animal research (7 (5 to 8)) and thought that about 50% (32–70) of animal experiments are published. Employees (n = 21) of for-profit organizations estimated that 10% (5 to 50) are published. Lack of statistical significance (4 (4 to 5)), technical problems (4 (3 to 4)), supervisors (4 (3 to 5)) and peer reviewers (4 (3 to 5)) were considered important reasons for non-publication (all on 5-point scales). Respondents thought that mandatory publication of study protocols and results, or the reasons why no results were obtained, may increase scientific progress but expected increased bureaucracy. These opinions did not depend on size of the animal used, seniority of the respondent or type of research. Conclusions Non-publication of “negative” results appears to be prevalent in laboratory animal research. If statistical significance is indeed a main driver of publication, the collective literature on animal experimentation will be biased. This will impede the performance of valid literature syntheses. Effective, yet efficient systems should be explored to

A Research-Inspired Laboratory Sequence Investigating Acquired Drug Resistance

ERIC Educational Resources Information Center

Taylor, Elizabeth Vogel; Fortune, Jennifer A.; Drennan, Catherine L.

2010-01-01

Here, we present a six-session laboratory exercise designed to introduce students to standard biochemical techniques in the context of investigating a high impact research topic, acquired resistance to the cancer drug Gleevec. Students express a Gleevec-resistant mutant of the Abelson tyrosine kinase domain, the active domain of an oncogenic…

IBBR and Frederick National Laboratory Collaborate to Study Vaccine-Boosting Compounds | Frederick National Laboratory for Cancer Research

Cancer.gov

The Frederick National Laboratory and the University of Maryland’s Institute for Bioscience and Biotechnology Research (IBBR) will work under a formal collaboration to evaluate the effectiveness of new compounds that might be used to enhance the im

United States Air Force Summer Research Program -- 1992 High School Apprenticeship Program (HSAP) Reports. Volume 13. Phillips Laboratory

DTIC Science & Technology

1992-01-01

Research Program Phillips Laboratory I4oJ A*6Iv4 Sponsored by: Air Force Office of Scientific Research Kirtland Air ...UNITED STATES AIR FORCE SUMMER RESEARCH PROGki"A -- 1992 HIGH SCHOOL APPRENTICESHIP PROGRAM (HSAP) REPORTS VOLUME 13 (t PHILLIPS LABORATORY . RESEARCH ...Arlington High School Final Report for: Summer Research Program Geophysics Directorate Phillips Laboratory

75 FR 15675 - Professional Research Experience Program in Chemical Science and Technology Laboratory...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-30

... in physics, chemistry, mathematics, computer science, or engineering. Institutions should have a 4..., mathematics, computer science, or engineering with work experiences in laboratories or other settings...-0141-01] Professional Research Experience Program in Chemical Science and Technology Laboratory...

The Advanced Interdisciplinary Research Laboratory: A Student Team Approach to the Fourth-Year Research Thesis Project Experience

ERIC Educational Resources Information Center

Piunno, Paul A. E.; Boyd, Cleo; Barzda, Virginijus; Gradinaru, Claudiu C.; Krull, Ulrich J.; Stefanovic, Sasa; Stewart, Bryan

2014-01-01

The advanced interdisciplinary research laboratory (AIRLab) represents a novel, effective, and motivational course designed from the interdisciplinary research interests of chemistry, physics, biology, and education development faculty members as an alternative to the independent thesis project experience. Student teams are assembled to work…

U.S. Army Aeromedical Research Laboratory Annual Progress Report FY 1986

DTIC Science & Technology

1986-10-01

19 Contracts ................................................. 19 Small Business Innovation...universities and businesses which parallels the research requirements of the laboratories under the USAMRDC command. Because of the scientific manpower...Software is being written to allow double entry verification of data. 2) Small business innovation research Each year, in compliance with the Small

New Webpage Brings Increased Visibility to Frederick National Laboratory Subcontracting Opportunities | Frederick National Laboratory for Cancer Research

Cancer.gov

A new webpage will now make it easier for small businesses and others to find and apply for Frederick National Laboratory for Cancer Research business opportunities. The new solicitations page, which launched on the Frederick National Lab website Aug

Cocaine Use among the College Age Group: Biological and Psychological Effects--Clinical and Laboratory Research Findings.

ERIC Educational Resources Information Center

Nicholi, Armand M., Jr.

1984-01-01

Knowledge about cocaine's effect on the human mind and body is limited and not clearly documented. This article discusses various biological and psychological effects of the drug based on clinical and laboratory studies of man. (Author/DF)

LABORATORY DIRECTED RESEARCH AND DEVELOPMENT ANNUAL REPORT TO THE DEPARTMENT OF ENERGY - DECEMBER 2004

DOE Office of Scientific and Technical Information (OSTI.GOV)

FOX,K.J.

Brookhaven National (BNL) Laboratory is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, under contract with the U. S. Department of Energy. BNL's total annual budget has averaged about $460 million. There are about 2,800 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually inmore » March, as required by DOE Order 4 13.2A, ''Laboratory Directed Research and Development,'' January 8, 2001, and the LDRD Annual Report guidance, updated February 12, 1999. The LDRD Program obtains its funds through the Laboratory overhead pool and operates under the authority of DOE Order 413.2A. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new ''fundable'' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research ''which could lead to new programs, projects, and directions'' for the Laboratory. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new science and technology ideas, which becomes a major factor in achieving and maintaining staff

How and Why I Built a Research Laboratory

NASA Astrophysics Data System (ADS)

Lakhdar, Zohra Ben

2005-10-01

The 2005 L'ORÉAL-UNESCO award for women in physics recognized Zohra Ben Lakhdar's contributions to research in Tunisia. But when Professor Ben Lakhdar was a young girl in 1950s Tunisia, girls did not go to school beyond the elementary grades, and she found herself under the tutelage of her mother learning how to take care of a family and home. Tunisia's independence in 1956 changed that, and Professor Ben Lakhdar soon became the only girl in an all-boys' college. In 1978 when she returned to Tunisia after earning her PhD in Paris, fewer than 10 Tunisians were doing research. But the number of students in the country was increasing and trained teachers were needed. Developing the capability to do research in Tunisia was urgent. So Professor Ben Lakhdar built a research laboratory in Tunisia. This paper tells the story.

EPA/ORD NATIONAL EXPOSURE RESEARCH LABORATORY MEASUREMENT SCIENCE SUPPORT FOR HOMELAND SECURITY

EPA Science Inventory

This product describes the National Exposure Research Laboratory research and development support for homeland security through the proposed National Exposure Measurements Center (NEMC). Key NEMC functional areas depicted in this poster are: standardized analytical method develo...

Software engineering laboratory series: Annotated bibliography of software engineering laboratory literature

NASA Technical Reports Server (NTRS)

Morusiewicz, Linda; Valett, Jon

1992-01-01

This document is an annotated bibliography of technical papers, documents, and memorandums produced by or related to the Software Engineering Laboratory. More than 100 publications are summarized. These publications cover many areas of software engineering and range from research reports to software documentation. This document has been updated and reorganized substantially since the original version (SEL-82-006, November 1982). All materials have been grouped into eight general subject areas for easy reference: (1) the Software Engineering Laboratory; (2) the Software Engineering Laboratory: Software Development Documents; (3) Software Tools; (4) Software Models; (5) Software Measurement; (6) Technology Evaluations; (7) Ada Technology; and (8) Data Collection. This document contains an index of these publications classified by individual author.

Ethical Issues in the Research of Group Work

ERIC Educational Resources Information Center

Goodrich, Kristopher M.; Luke, Melissa

2017-01-01

This article provides a primer for researchers exploring ethical issues in the research of group work. The article begins with an exploration of relevant ethical issues through the research process and current standards guiding its practice. Next, the authors identify resources that group work researchers can consult prior to constructing their…

Escambia Experimental Forest: A Living Laboratory for Long Term Longleaf Pine Research

Treesearch

Charles K. McMahon

2000-01-01

Experimental Forests have been used for many years by research organizations as "living laboratories" where long-term research studies can be conducted. For forestry and related natural resources research, "long term" can often mean decades of continuous study before meaningful results can be obtained. The Escambia Experimental Forest was...

Collaborative translational research leading to multicenter clinical trials in Duchenne muscular dystrophy: the Cooperative International Neuromuscular Research Group (CINRG).

PubMed

Escolar, Diana M; Henricson, Erik K; Pasquali, Livia; Gorni, Ksenija; Hoffman, Eric P

2002-10-01

Progress in the development of rationally based therapies for Duchenne muscular dystrophy has been accelerated by encouraging multidisciplinary, multi-institutional collaboration between basic science and clinical investigators in the Cooperative International Research Group. We combined existing research efforts in pathophysiology by a gene expression profiling laboratory with the efforts of animal facilities capable of conducting high-throughput drug screening and toxicity testing to identify safe and effective drug compounds that target different parts of the pathophysiologic cascade in a genome-wide drug discovery approach. Simultaneously, we developed a clinical trial coordinating center and an international network of collaborating physicians and clinics where those drugs could be tested in large-scale clinical trials. We hope that by bringing together investigators at these facilities and providing the infrastructure to support their research, we can rapidly move new bench discoveries through animal model screening and into therapeutic testing in humans in a safe, timely and cost-effective setting.

Review of Army Research Laboratory Programs for Historically Black Colleges and Universities and Minority Institutions

ERIC Educational Resources Information Center

National Academies Press, 2014

2014-01-01

"Review of Army Research Laboratory Programs for Historically Black Colleges and Universities and Minority Institutions" examines the ways in which historically black colleges and universities and minority institutions have used the Army Research Laboratory (ARL) funds to enhance the science, technology, engineering, and mathematics…

National Risk Management Research Laboratory Strategic plan and Implementation - Overview

EPA Science Inventory

This publication provides an overview of the strategic plan recently developed by the National Risk Management Research Laboratory (NRMRL). It includes a description of NRMRL's mission and goals and their alignment with Agency goals. Additionally, the overview contains a brief se...

Feminist Research Methodology Groups: Origins, Forms, Functions.

ERIC Educational Resources Information Center

Reinharz, Shulamit

Feminist Research Methodology Groups (FRMGs) have developed as a specific type of women's group in which feminist academics can find supportive audiences for their work while contributing to a feminist redefinition of research methods. An analysis of two FRMGs reveals common characteristics, dynamics, and outcomes. Both were limited to small…

The NASA/NSERC Student Airborne Research Program Land Focus Group - a Paid Training Program in Multi-Disciplinary STEM Research for Terrestrial Remote Sensing

NASA Astrophysics Data System (ADS)

Kefauver, S. C.; Ustin, S.; Davey, S. W.; Furey, B. J.; Gartner, A.; Kurzweil, D.; Siebach, K. L.; Slawsky, L.; Snyder, E.; Trammell, J.; Young, J.; Schaller, E.; Shetter, R. E.

2011-12-01

The Student Airborne Research Program (SARP) of the National Aeronautics and Space Administration (NASA) and the National Suborbital Education and Research Center (NSERC) is a unique six week multidisciplinary paid training program which directly integrates students into the forefront of airborne remote sensing science. Students were briefly trained with one week of lectures and laboratory exercises and then immediately incorporated into ongoing research projects which benefit from access to the DC-8 airborne platform and the MODIS-ASTER Airborne Simulator (MASTER) sensor. Students were split into three major topical categories of Land, Ocean, and Air for the data collection and project portions of the program. This poster details the techniques and structure used for the student integration into ongoing research, professional development, hypothesis building and results as developed by the professor and mentor of the Land focus group. Upon assignment to the Land group, students were issued official research field protocols and split into four field specialty groups with additional specialty reading assignments. In the field each group spent more time in their respective specialty, but also participated in all field techniques through pairings with UC Davis research team members using midday rotations. After the field campaign, each specialty group then gave summary presentations on the techniques, preliminary results, and significance to overall group objectives of their specialty. Then students were required to submit project proposals within the bounds of Land airborne remote sensing science and encouraging, but not requiring the use of the field campaign data. These proposals are then reviewed by the professor and mentor and students are met with one by one to discuss the skills of each student and objectives of the proposed research project. The students then work under the supervision of the mentor and benefit again from professor feedback in a formal

Learning from Older Citizens' Research Groups

ERIC Educational Resources Information Center

Munn-Giddings, Carol; McVicar, Andy; Boyce, Melanie; O'Brien, Niamh

2016-01-01

This article adds to an ongoing conversation in gerontology about the importance of training and involving older people in research. Currently, the literature rarely distinguishes between the one-off involvement of older citizens in research projects and the development of research groups led by older people that sustain over time as well as the…

Sequim Marine Research Laboratory routine environmental measurements during CY-1977

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fix, J.J.; Blumer, P.J.

1978-06-01

Beginning in 1976, a routine environmental program was established at the Marine Research Laboratory (MRL) at Sequim, Washington. The program is intended to demonstrate the negligible impact of current MRL operations on the surrounding environs and to provide baseline data through which any cumulative impact could be detected. The sampling frequency is greater during the first 2 years of the program to provide sufficient initial information to allow reliable estimates of observed radionuclide concentrations and to construct a long-term sampling program. The program is designed, primarily, to determine levels of radioactivity present in selected biota in Sequim Bay. The biotamore » were selected because of their presence near the laboratory and their capacity to concentrate trace elements. Other samples were obtained to determine the radionuclides in Sequim Bay and laboratory drinking water, as well as the ambient radiation exposure levels and surface deposition of fallout radionuclides for the laboratory area. Appendix A provides a summary of the analytical methods used. The present document includes data obtained during CY 1977 in addition to CY-1976 data published previously.« less

Artist rendition of the planned Space Experiment Research and Processing Laboratory

NASA Technical Reports Server (NTRS)

2000-01-01

The preliminary design for the Space Experiment Research and Processing Laboratory (SERPL) at Kennedy Space Center is shown in this artist's rendition. The SERPL is a planned 100,000-square- foot laboratory that will provide expanded and upgraded facilities for hosting International Space Station experiment processing. In addition, it will provide better support for other biological and life sciences payload processing at KSC. It will serve as a magnet facility for a planned 400-acre Space Station Commerce Park.