A Study of the Effects of Microteaching Experiences Upon the Classroom Behavior of Social Studies Student Teachers.

ERIC Educational Resources Information Center

Limbacher, Philip C.

The hypotheses of this field study, conducted in connection with the Teaching Techniques Laboratory at the University of Illinois, were that student teachers who had participated in a supervised, laboratory, microteaching experience would: 1) receive more favorable pupil evaluations of an initial and final teaching effort on the Teacher…

Laboratory investigation of hydrated lime as an antistripping additive : final report.

DOT National Transportation Integrated Search

1983-01-01

The purpose of this laboratory study was to determine the effectiveness of hydrated lime as an antistripping additive when used in bituminous mixes incorporating aggregates frequently used in such mixes in Virginia. The application of 1% hydrated lim...

Study of Visual and Auditory Presentation in Dental Lecture and Laboratory Instruction. Final Report.

ERIC Educational Resources Information Center

Allen, William H.; And Others

This study compared the relative effectiveness of an automated teaching machine with instructor presented instruction in graduate dental teaching. The objectives were to: (1) determine the effects of 3 laboratory instructional procedures used in combination with 2 lectures on the acquisition of manual operative skills, the learning of information…

United States Air Force Summer Research Program -- 1993. Volume 8. Phillips Laboratory

DTIC Science & Technology

1993-12-01

Research Program Phillips Laboratory Kirtland Air Force Base Albuquerque. New Mexico Sponsored by...Best Available Copy UNITED STATES AIR FORCE SUMMER RESEARCH PROGRAM -- 1993 SUMMER RESEARCH PROGRAM FINAL REPORTS VOLUME 8 PHILLIPS LABORATORY ...Alabama Box 870344 Tuscaloosa, AL 35487-0344 Final Report for: Graduate Student Research Program Phillips Laboratory , Hanscom AFB Sponsored by: Air

Successful Sampling Strategy Advances Laboratory Studies of NMR Logging in Unconsolidated Aquifers

NASA Astrophysics Data System (ADS)

Behroozmand, Ahmad A.; Knight, Rosemary; Müller-Petke, Mike; Auken, Esben; Barfod, Adrian A. S.; Ferré, Ty P. A.; Vilhelmsen, Troels N.; Johnson, Carole D.; Christiansen, Anders V.

2017-11-01

The nuclear magnetic resonance (NMR) technique has become popular in groundwater studies because it responds directly to the presence and mobility of water in a porous medium. There is a need to conduct laboratory experiments to aid in the development of NMR hydraulic conductivity models, as is typically done in the petroleum industry. However, the challenge has been obtaining high-quality laboratory samples from unconsolidated aquifers. At a study site in Denmark, we employed sonic drilling, which minimizes the disturbance of the surrounding material, and extracted twelve 7.6 cm diameter samples for laboratory measurements. We present a detailed comparison of the acquired laboratory and logging NMR data. The agreement observed between the laboratory and logging data suggests that the methodologies proposed in this study provide good conditions for studying NMR measurements of unconsolidated near-surface aquifers. Finally, we show how laboratory sample size and condition impact the NMR measurements.

USAF Summer Research Program - 1994 Graduate Student Research Program Final Reports, Volume 8, Phillips Laboratory

DTIC Science & Technology

1994-12-01

Research Group at the Phillips Laboratory at Kirtland Air Force Base...for Summer Graduate Student Research Program Phillips Laboratory Sponsored by: Air Force Office of Scientific Research Boiling Air Force Base, DC...2390 S. York Street Denver, CO 80208-0177 Final Report for: Summer Faculty Research Program Phillips Laboratory Sponsored by: Air Force

Laboratory Astrophysics Using High Intensity Particle and Photon Beams

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Pisin

History has shown that the symbiosis between direct observations and laboratory studies is instrumental in the progress of astrophysics. Recent years have seen growing interests in the laboratory investigation of astrophysical phenomena that can be addressed by high densities and advancement of technologies in lasers as well as high-energy particle beams. We will give examples on how frontier phenomena such as black holes, supernovae, gamma ray bursts, ultra high-energy cosmic rays, etc., can be investigated in the laboratory setting. Finally, we describe a possible laboratory astrophysics facility to be developed at SLAC.

Identification of laboratory techniques to optimize Superpave HMA surface friction characteristics : final report, April 2010.

DOT National Transportation Integrated Search

2010-04-15

Wet pavement friction is known to be one of the most important roadway safety parameters. In this : research, frictional properties of flexible (asphalt) pavements were investigated. : As a part of this study, a laboratory device to polish asphalt sp...

Investigations in Computer-Aided Instruction and Computer-Aided Controls. Final Report.

ERIC Educational Resources Information Center

Rosenberg, R.C.; And Others

These research projects, designed to delve into certain relationships between humans and computers, are focused on computer-assisted instruction and on man-computer interaction. One study demonstrates that within the limits of formal engineering theory, a computer simulated laboratory (Dynamic Systems Laboratory) can be built in which freshmen…

Women's Experiences in the Engineering Laboratory in Japan

ERIC Educational Resources Information Center

Hosaka, Masako

2014-01-01

This qualitative study aims to examine Japanese women undergraduate engineering students' experiences of interacting with departmental peers of the same year in the laboratory setting by using interview data of 32 final-year students at two modestly selective national universities in Japan. Expectation state theory that explains unequal…

Field Study on Environmental Dredging Residuals: Ashtabula River; Volume I. Final Report

EPA Science Inventory

A partnership was formed in 2006 between the National Risk Management Research Laboratory (NRMRL) and the National Exposure Research Laboratory (NERL) of the U.S. Environmental Protection Agency's (U.S. EPA's) Office of Research and Development (ORD) and U.S. EPA's Great Lakes Na...

The small-scale treatability study sample exemption

DOE Office of Scientific and Technical Information (OSTI.GOV)

Coalgate, J.

1991-01-01

In 1981, the Environmental Protection Agency (EPA) issued an interim final rule that conditionally exempted waste samples collected solely for the purpose of monitoring or testing to determine their characteristics or composition'' from RCRA Subtitle C hazardous waste regulations. This exemption (40 CFR 261.4(d)) apples to the transportation of samples between the generator and testing laboratory, temporary storage of samples at the laboratory prior to and following testing, and storage at a laboratory for specific purposes such as an enforcement action. However, the exclusion did not include large-scale samples used in treatability studies or other testing at pilot plants ormore » other experimental facilities. As a result of comments received by the EPA subsequent to the issuance of the interim final rule, the EPA reopened the comment period on the interim final rule on September 18, 1987, and specifically requested comments on whether or not the sample exclusion should be expanded to include waste samples used in small-scale treatability studies. Almost all responders commented favorably on such a proposal. As a result, the EPA issued a final rule (53 FR 27290, July 19, 1988) conditionally exempting waste samples used in small-scale treatability studies from full regulation under Subtitle C of RCRA. The question of whether or not to extend the exclusion to larger scale as proposed by the Hazardous Waste Treatment Council was deferred until a later date. This information Brief summarizes the requirements of the small-scale treatability exemption.« less

The Orthopaedic Training Study, Phase II 1968-1972. Final Report Supplement, Psychomotor Skills, Part B.

ERIC Educational Resources Information Center

Olson, Carl J.; And Others

This document, as a supplement to the final report of the Orthopaedic Training Study, presents a discussion of the rationale behind the implementation of a laboratory course in psychomotor skills development for medical students. Medical educators examined resident training in terms of 3 components of cognitive elements of learning: cognitive,…

USAF Summer Research Program - 1993 Graduate Student Research Program Final Reports, Volume 8, Phillips Laboratory

DTIC Science & Technology

1994-12-01

Research Program Phillips Laboratory Kirtland Air Force Base Albuquerque, New Mexico Sponsored by: Air ...Summer Research Program Phillips Laboratory Sponsored by. Air Force Office of Scientific Research Kirtland Air Force Base, Albuquerque, New Mexico...UNITED STATES AIR FORCE SUMMER RESEARCH PROGRAM -- 1993 SUMMER RESEARCH PROGRAM FINAL REPORTS VOLUME 8

The Effectiveness of Active and Traditional Teaching Techniques in the Orthopedic Assessment Laboratory

ERIC Educational Resources Information Center

Nottingham, Sara; Verscheure, Susan

2010-01-01

Active learning is a teaching methodology with a focus on student-centered learning that engages students in the educational process. This study implemented active learning techniques in an orthopedic assessment laboratory, and the effects of these teaching techniques. Mean scores from written exams, practical exams, and final course evaluations…

Unlocking the Laboratory: Autonomous Wireless Sensor Authentication in Practice

ERIC Educational Resources Information Center

Huggard, Meriel; McGoldrick, Ciaran

2013-01-01

Purpose: The purpose of this study is to evaluate a practical laboratory task where final year undergraduate students design, implement and validate an inferred security wireless sensor access system. Design/methodology/approach: The quality of the learning and technical environment was evaluated from a number of perspectives using a mixed methods…

The performance assessment of undergraduate students in physics laboratory by using guided inquiry

NASA Astrophysics Data System (ADS)

Mubarok, H.; Lutfiyah, A.; Kholiq, A.; Suprapto, N.; Putri, N. P.

2018-03-01

The performance assessment of basic physics experiment among undergraduate physics students which includes three stages: pre-laboratory, conducting experiment and final report was explored in this study. The research used a descriptive quantitative approach by utilizing guidebook of basic physics experiment. The findings showed that (1) the performance of pre-laboratory rate among undergraduate physics students in good category (average score = 77.55), which includes the ability of undergraduate physics students’ theory before they were doing the experiment. (2) The performance of conducting experiment was in good category (average score = 78.33). (3) While the performance of final report was in moderate category (average score = 73.73), with the biggest weakness at how to analyse and to discuss the data and writing the abstract.

KEY COMPARISON: Final report on CCQM-K44: Trace elements in sewage sludge

NASA Astrophysics Data System (ADS)

Aregbe, Y.; Taylor, P. D. P.

2009-01-01

CCQM-K44 was an activity of the Inorganic Analysis Working Group (IAWG) of CCQM and was coordinated by the Joint Research Centre-Institute for Reference Materials and Measurements (IRMM, Geel, Belgium) of the European Commission (EC). In CCQM-K44 the amount contents of Cd, Cr, Cu, Pb, Hg, Ni and Zn in sewage sludge were the measurands under investigation. Results were reported by six national metrology institutes (NMIs). During the CCQM-IAWG Spring meeting in Paris, April 2006, the approaches to calculate the KCRV as proposed by the coordinating laboratory were discussed and agreed on. The final report was submitted in June 2006. After the final report had been submitted to the CCQM in June 2006 the coordinating laboratory was informed that MIRS/IJS was not a designated institute and therefore could not represent the Slovenian NMI in CCQM-K44. This was contrary to what MIRS confirmed to the coordinating laboratory at the beginning of CCQM-K44. After several discussions between MIRS and the CCQM the coordinating laboratory was asked to amend the final report accordingly. In this revised version of the CCQM-K44 final report the results of MIRS/IJS were taken out of CCQM-K44 and included in the pilot study CCQM-P70, which was organised in parallel to CCQM-K44. Due to the limited number of participants compared to previous key comparisons the mixture model median (MM-median) of all reported results could not be applied as KCRV for all the measurands. During the CCQM-IAWG Spring meeting in Paris, April 2006, the approaches to calculate the KCRV as proposed by the coordinating laboratory were discussed and first agreed on. As a result the final report and degrees of equivalence were finalised and submitted to the CCQM. Subsequent discussions between the IAWG and the CCQM were held, resulting in a different approach as proposed by the coordinating laboratory. Particularly Maurice Cox from NPL recommended the weighted mean and its standard uncertainty (k = 1) as KCRV independently of the number of participants. The coordinating laboratory agreed to this proposal and amended the final report using the weighted mean KCRV in CCQM-K44 for all measurands. The reported results of the NMIs fall within a range of ±4% deviation from the KCRVs for Cr and Hg. For Pb and Cu the NMIs reported results within ±9%. For Zn the spread of all laboratories but one is ±2%. For Cd two of the three participating NMIs reported results within ±0.2% from the KCRV. The coordinating laboratory agreed with BAM, CENAM and LNE that due to the observed spread of the results Ni will be reported as inconclusive and no KCRV or degrees of equivalence for Ni will be included in this report. The methods applied were isotope dilution mass spectrometry (IDMS) using quadrupole inductively coupled plasma-mass spectrometry (ICP-MS) or thermal ionisation mass spectrometry (TIMS), external calibration using atomic absorption spectrometry (AAS). K0-neutron activation analysis (k0-NAA) and x-ray fluorescence (XRF) were also used as analytical techniques. This final report presents the participants' results in CCQM-K44 for all analytes under investigation. In Annex 1, the results with the KCRV are presented. In Annex 2, the questionnaire data are presented. The pilot study CCQM-P70 was carried out in parallel to this key comparison for the same measurands in the same sewage sludge material. Participation was meant for IAWG members, who did not immediately want to report results in a key comparison, and invited expert laboratories. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).

Ames Laboratory site environmental report, calendar year 1988

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mathison, L.K.

1989-05-01

The summarized data and conclusions from the Ames Laboratory environmental monitoring program are presented in this Annual Site Environmental Report. Ames Laboratory is located on the campus of Iowa State University (ISU) and occupies several buildings owned by the Department of Energy. A study is being conducted to identify environmental sampling methods which can characterize and separate the impact of Ames Laboratory's campus activities and that of ISU. This will enable the Laboratory to determine what possible impact it's operations may be having to the environment, if any. Two Pollution Abatement projects were begun in 1988. They were: removal ofmore » thorium contaminated soil resulting from a historical release of thorium at the Laboratory, to the Ames, Iowa Water Pollution Control (sewage) Plant and demolition of a small Blockhouse'' constructed of concrete block which had been used for low level radioactive waste handling. The contaminated soil has been removed and transported to Hanford, WA for disposal. A final site radiological survey for thorium is pending. In addition, contaminated debris was transported to Hanford, WA for disposal and a final site survey is pending. 7 refs., 4 figs., 1 tab.« less

Assessing student understanding of measurement and uncertainty

NASA Astrophysics Data System (ADS)

Jirungnimitsakul, S.; Wattanakasiwich, P.

2017-09-01

The objectives of this study were to develop and assess student understanding of measurement and uncertainty. A test has been adapted and translated from the Laboratory Data Analysis Instrument (LDAI) test, consists of 25 questions focused on three topics including measures of central tendency, experimental errors and uncertainties, and fitting regression lines. The test was evaluated its content validity by three physics experts in teaching physics laboratory. In the pilot study, Thai LDAI was administered to 93 freshmen enrolled in a fundamental physics laboratory course. The final draft of the test was administered to three groups—45 freshmen taking fundamental physics laboratory, 16 sophomores taking intermediated physics laboratory and 21 juniors taking advanced physics laboratory at Chiang Mai University. As results, we found that the freshmen had difficulties in experimental errors and uncertainties. Most students had problems with fitting regression lines. These results will be used to improve teaching and learning physics laboratory for physics students in the department.

USAF Summer Research Program - 1993 High School Apprenticeship Program Final Reports, Volume 12, Armstrong Laboratory

DTIC Science & Technology

1993-12-01

on Panasonic TLD . Panasonic Industrial Company; Secaucus, New Jersey. 5. Thurlow, Ronald M. "Neutron Dosimetry Using a Panasonic Thermoluminescent...Radiation Dosimetry Branch Brooks Air Force Base San Antonio, Texas 78235 Final Report for: AFOSR Summer Research Program Armstrong Laboratory Sponsored...Associate Radiation Dosimetry Branch Armstrong Laboratory Abstract In an attempt to improve personnel monitoring for neutron emissions, Panasonic has

The Essential Role for Laboratory Studies in Atmospheric Chemistry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burkholder, James B.; Abbatt, Jonathan P. D.; Barnes, Ian

Laboratory studies of atmospheric chemistry characterize the nature of atmospherically relevant processes down to the molecular level, providing fundamental information used to assess how human activities drive environmental phenomena such as climate change, urban air pollution, ecosystem health, indoor air quality, and stratospheric ozone depletion. Laboratory studies have a central role in addressing the incomplete fundamental knowledge of atmospheric chemistry. This paper highlights the evolving science needs for this community and emphasizes how our knowledge is far from complete, hindering our ability to predict the future state of our atmosphere and to respond to emerging global environmental change issues. Finally,more » laboratory studies provide rich opportunities to expand our understanding of the atmosphere via collaborative research with the modeling and field measurement communities, and with neighboring disciplines.« less

The testing effect for mediator final test cues and related final test cues in online and laboratory experiments.

PubMed

Coppens, Leonora C; Verkoeijen, Peter P J L; Bouwmeester, Samantha; Rikers, Remy M J P

2016-05-31

The testing effect is the finding that information that is retrieved during learning is more often correctly retrieved on a final test than information that is restudied. According to the semantic mediator hypothesis the testing effect arises because retrieval practice of cue-target pairs (mother-child) activates semantically related mediators (father) more than restudying. Hence, the mediator-target (father-child) association should be stronger for retrieved than restudied pairs. Indeed, Carpenter (2011) found a larger testing effect when participants received mediators (father) than when they received target-related words (birth) as final test cues. The present study started as an attempt to test an alternative account of Carpenter's results. However, it turned into a series of conceptual (Experiment 1) and direct (Experiment 2 and 3) replications conducted with online samples. The results of these online replications were compared with those of similar existing laboratory experiments through small-scale meta-analyses. The results showed that (1) the magnitude of the raw mediator testing effect advantage is comparable for online and laboratory experiments, (2) in both online and laboratory experiments the magnitude of the raw mediator testing effect advantage is smaller than in Carpenter's original experiment, and (3) the testing effect for related cues varies considerably between online experiments. The variability in the testing effect for related cues in online experiments could point toward moderators of the related cue short-term testing effect. The raw mediator testing effect advantage is smaller than in Carpenter's original experiment.

Life sciences payload definition and integration study. Volume 2: Requirements, design, and planning studies for the carry-on laboratories. [for Spacelab

NASA Technical Reports Server (NTRS)

1974-01-01

The task phase concerned with the requirements, design, and planning studies for the carry-on laboratory (COL) began with a definition of biomedical research areas and candidate research equipment, and then went on to develop conceptual layouts for COL which were each evaluated in order to arrive at a final conceptual design. Each step in this design/evaluation process concerned itself with man/systems integration research and hardware, and life support and protective systems research and equipment selection. COL integration studies were also conducted and include attention to electrical power and data management requirements, operational considerations, and shuttle/Spacelab interface specifications. A COL program schedule was compiled, and a cost analysis was finalized which takes into account work breakdown, annual funding, and cost reduction guidelines.

Final Progress Report for Collaborative Research: Aging of Black Carbon during Atmospheric Transport: Understanding Results from the DOE’s 2010 CARES and 2012 ClearfLo Campaigns

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mazzoleni, Claudio; Subramanian, R.

2016-08-31

Over the course of this project, we have analyzed data and samples from the Carbonaceous Aerosol and Radiative Effects Study (CARES) and the Clear air for London (ClearfLo) campaign, as well as conducted or participated in laboratory experiments designed to better understand black carbon mixing state and climate-relevant properties. The laboratory campaigns took place at the Pacific Northwest National Laboratory and Carnegie Mellon University to study various climate-relevant aerosol properties of different sources of soot mixing with secondary organic aerosol precursors. Results from some of these activities were summarized in the previous progress report. This final report presents the manuscriptsmore » that have been published (many in the period since the last progress report), lists presentations at different conferences based on grant-related activities, and presents some results that are likely to be submitted for publication in the near future.« less

Soil-cement study : final report.

DOT National Transportation Integrated Search

1973-11-01

This study consisted of an examination of the compressive strengths of soil-cement mixtures on 15 construction projects from the standpoint of design and actual achievement. The laboratory design test was examined closely along with the present field...

Integrated Data Collection Analysis (IDCA) Program - Final Review September 12, 2012 at DHS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sandstrom, Mary M.; Brown, Geoffrey W.; Warner, Kirstin F.

The Integrated Data Collection Analysis (IDCA) program conducted a final program review at the Department of Homeland Security on September 12, 2012. The review was focused on the results of the program over the complete performance period. A summary presentation delineating the accomplished tasks started the meeting, followed by technical presentations on various issues that arose during the performance period. The presentations were completed with a statistical evaluation of the testing results from all the participants in the IDCA Proficiency Test study. The meeting closed with a discussion of potential sources of funding for continuing work to resolve some ofmore » these technical issues. This effort, funded by the Department of Homeland Security (DHS), put the issues of safe handling of these materials in perspective with standard military explosives. The study added Small-Scale Safety and Thermal (SSST) testing results for a broad suite of different HMEs to the literature, and suggested new guidelines and methods to develop safe handling practices for HMEs. Each participating testing laboratory used identical test materials and preparation methods wherever possible. Note, however, the test procedures differ among the laboratories. The results were compared among the laboratories and then compared to historical data from various sources. The testing performers involved were Lawrence Livermore National Laboratory (LLNL), Los Alamos National Laboratory (LANL), Naval Surface Warfare Center, Indian Head Division (NSWC IHD), Sandia National Laboratories (SNL), and Air Force Research Laboratory, Tyndall AFB (AFRL/RXQL). These tests were conducted as a proficiency study in order to establish some consistency in test protocols, procedures, and experiments and to compare results when these testing variables cannot be made consistent.« less

Knowledge Retention for Computer Simulations: A study comparing virtual and hands-on laboratories

NASA Astrophysics Data System (ADS)

Croom, John R., III

The use of virtual laboratories has the potential to change physics education. These low-cost, interactive computer activities interest students, allow for easy setup, and give educators a way to teach laboratory based online classes. This study investigated whether virtual laboratories could replace traditional hands-on laboratories and whether students could retain the same long-term knowledge in virtual laboratories as compared to hands-on laboratories. This study is a quantitative quasi-experiment that used a multiple posttest design to determine if students using virtual laboratories would retain the same knowledge as students who performed hands-on laboratories after 9 weeks. The study was composed of 336 students from 14 school districts. Students had their performances on the laboratories and their retention of the laboratories compared to a series of factors that might have affected their retention using a pretest and two posttests, which were compared using a t test. The results showed no significant difference in short-term learning between the hands-on laboratory groups and virtual laboratory groups. There was, however, a significant difference (p = .005) between the groups in long-term retention; students in the hands-on laboratory groups retained more information than those in the virtual laboratory groups. These results suggest that long-term learning is enhanced when a laboratory contains a hands-on component. Finally, the results showed that both groups of students felt their particular laboratory style was superior to the alternative method. The findings of this study can be used to improve the integration of virtual laboratories into science curriculum.

Evaluation of the Regional Educational Laboratories. Final Report. NCEE 2015-4008

ERIC Educational Resources Information Center

Carison, Elaine; Bitterman, Amy; Zhang, Xiaodong; Lee, Hyunshik; Gutmann, Babette; Wills, Kerri; Sinclair, Beth

2015-01-01

This report is the second from the congressionally-mandated evaluation of the Regional Educational Laboratory (REL) program authorized by the Education Sciences Reform Act (P.L. 107-279). For this report, 8 (out of 24) impact study reports produced by the RELs under their 2006-2011 contracts and published by IES were rated by expert panels for…

Final definition and preliminary design study for the initial atmospheric cloud physics laboratory, a spacelab mission payload

NASA Technical Reports Server (NTRS)

1976-01-01

The Atmospheric Cloud Physics Laboratory (ACPL) task flow is shown. Current progress is identified. The requirements generated in task 1 have been used to formulate an initial ACPL baseline design concept. ACPL design/functional features are illustrated. A timetable is presented of the routines for ACPL integration with the spacelab system.

KEY COMPARISON: Final report of the SIM 60Co absorbed-dose-to-water comparison SIM.RI(I)-K4

NASA Astrophysics Data System (ADS)

Ross, C. K.; Shortt, K. R.; Saravi, M.; Meghzifene, A.; Tovar, V. M.; Barbosa, R. A.; da Silva, C. N.; Carrizales, L.; Seltzer, S. M.

2008-01-01

Transfer chambers were used to compare the standards for 60Co absorbed dose to water maintained by seven laboratories. Six of the laboratories were members of the Sistema Interamericano de Metrología (SIM) regional metrology organization while the seventh was the International Atomic Energy Agency (IAEA) laboratory in Vienna. The National Research Council (NRC) acted as the pilot laboratory for the comparison. Because of the participation of laboratories holding primary standards, the comparison results could be linked to the key comparison reference value maintained by the Bureau International des Poids et Mesures (BIPM). The results for all laboratories were within the expanded uncertainty (two standard deviations) of the reference value. The estimated relative standard uncertainty on the comparison between any pair of laboratories ranged from 0.6% to 1.4%. The largest discrepancy between any two laboratories was 1.3%. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI Section I, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).

KEY COMPARISON: Final report of the SIM 60Co air-kerma comparison SIM.RI(I)-K1

NASA Astrophysics Data System (ADS)

Ross, C. K.; Shortt, K. R.; Saravi, M.; Meghzifene, A.; Tovar, V. M.; Barbosa, R. A.; da Silva, C. N.; Carrizales, L.; Seltzer, S. M.

2008-01-01

Transfer chambers were used to compare the standards for 60Co air kerma maintained by seven laboratories. Six of the laboratories are members of the Sistema Interamericano de Metrología (SIM) regional metrology organization while the seventh is the International Atomic Energy Agency (IAEA) laboratory in Vienna. The National Research Council (NRC) acted as the pilot laboratory for the comparison. Because of the participation of laboratories holding primary standards, the comparison results could be linked to the key comparison reference value maintained by the Bureau International des Poids et Mesures (BIPM). The results for all laboratories were within the expanded uncertainty (two standard deviations) of the reference value. The estimated relative standard uncertainty of the comparison between any pair of laboratories ranged from 0.5% to 1.0%. The largest discrepancy between any two laboratories was 1.0%. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI Section I, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).

Life sciences payload definition and integration study. Volume 3: Preliminary equipment item specification catalog for the carry-on laboratories. [for Spacelab

NASA Technical Reports Server (NTRS)

1974-01-01

All general purpose equipment items contained in the final carry-on laboratory (COL) design concepts are described in terms of specific requirements identified for COL use, hardware status, and technical parameters such as weight, volume, power, range, and precision. Estimated costs for each item are given, along with projected development times.

The Influence of Laboratory Instruction on Science Achievement and Attitude toward Science among Ninth Grade Students across Gender Differences.

ERIC Educational Resources Information Center

Freedman, Michael P.

This study investigated the use of a hands-on laboratory program as a means of improving attitude toward science and increasing achievement levels in science knowledge among students in a ninth grade physical science course. Using a posttest-only control group design, a curriculum referenced objective final examination was used to measure student…

Modeling the microstructural changes during hot tandem rolling of AA5 XXX aluminum alloys: Part I. Microstructural evolution

NASA Astrophysics Data System (ADS)

Wells, M. A.; Samarasekera, I. V.; Brimacombe, J. K.; Hawbolt, E. B.; Lloyd, D. J.

1998-06-01

A comprehensive mathematical model of the hot tandem rolling process for aluminum alloys has been developed. Reflecting the complex thermomechanical and microstructural changes effected in the alloys during rolling, the model incorporated heat flow, plastic deformation, kinetics of static recrystallization, final recrystallized grain size, and texture evolution. The results of this microstructural engineering study, combining computer modeling, laboratory tests, and industrial measurements, are presented in three parts. In this Part I, laboratory measurements of static recrystallization kinetics and final recrystallized grain size are described for AA5182 and AA5052 aluminum alloys and expressed quantitatively by semiempirical equations. In Part II, laboratory measurements of the texture evolution during static recrystallization are described for each of the alloys and expressed mathematically using a modified form of the Avrami equation. Finally, Part III of this article describes the development of an overall mathematical model for an industrial aluminum hot tandem rolling process which incorporates the microstructure and texture equations developed and the model validation using industrial data. The laboratory measurements for the microstructural evolution were carried out using industrially rolled material and a state-of-the-art plane strain compression tester at Alcan International. Each sample was given a single deformation and heat treated in a salt bath at 400 °C for various lengths of time to effect different levels of recrystallization in the samples. The range of hot-working conditions used for the laboratory study was chosen to represent conditions typically seen in industrial aluminum hot tandem rolling processes, i.e., deformation temperatures of 350 °C to 500 °C, strain rates of 0.5 to 100 seconds and total strains of 0.5 to 2.0. The semiempirical equations developed indicated that both the recrystallization kinetics and the final recrystallized grain size were dependent on the deformation history of the material i.e., total strain and Zener-Hollomon parameter ( Z), where Z = dot \\varepsilon exp left( {{Q_{def} }/{RT_{def }}} right) and time at the recrystallization temperature.

Variable Dynamic Testbed Vehicle Study, Final Report, Volume II: Technical Results

DOT National Transportation Integrated Search

1994-08-30

THE NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION (NHTSA) COMMISSIONED THE JET PROPULSION LABORATORY (JPL) TO CONDUCT A STUDY OF AN INSTRUMENTED TEST VEHICLE THAT MAY SATISFY A NUMBER OF REQUIREMENTS FOR NHTSA AS WELL AS OTHERS DOING WORK ASSOCIATED...

Erosion evaluation study : final report.

DOT National Transportation Integrated Search

1974-06-01

This study concerned with attempting to develop a laboratory procedure by which products can be evaluated, as quickly as possible after they appear on the market, in order to screen them so that the best ones can be further tested in the field. : Pri...

Personal epistemological growth in a college chemistry laboratory environment

NASA Astrophysics Data System (ADS)

Keen-Rocha, Linda S.

The nature of this study was to explore changes in beliefs and lay a foundation for focusing on more specific features of reasoning related to personal epistemological and NOS beliefs in light of specific science laboratory instructional pedagogical practices (e.g., pre- and post-laboratory activities, laboratory work) for future research. This research employed a mixed methodology, foregrounding qualitative data. The total population consisted of 56 students enrolled in several sections of a general chemistry laboratory course, with the qualitative analysis focusing on the in-depth interviews. A quantitative NOS and epistemological beliefs measure was administered pre- and post-instruction. These measures were triangulated with pre-post interviews to assure the rigor of the descriptions generated. Although little quantitative change in NOS was observed from the pre-post NSKS assessment a more noticeable qualitative change was reflected by the participants during their final interviews. The NSKS results: the mean gain scores for the overall score and all dimensions, except for amoral were found to be significant at p ≤ .05. However there was a more moderate change in the populations' broader epistemological beliefs (EBAPS) which was supported during the final interviews. The EBAPS results: the mean gain scores for the overall score and all dimensions, except for the source of ability to learn were found to be significant at p ≤ .05. The participants' identified the laboratory work as the most effective instructional feature followed by the post-laboratory activities. The pre-laboratory was identified as being the least effective feature. The participants suggested the laboratory work offered real-life experiences, group discussions, and teamwork which added understanding and meaning to their learning. The post-laboratory was viewed as necessary in tying all the information together and being able to see the bigger picture. What one cannot infer at this point is whether these belief changes and beliefs about laboratory instruction are enduring or whether some participants are simply more adaptable than others are to the learning environment. More research studies are needed to investigate the effects of laboratory instruction on student beliefs and understanding.

Final Report Bald and Golden Eagle Territory Surveys for the Lawrence Livermore National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fratanduono, M. L.

2014-11-25

Garcia and Associates (GANDA) was contracted by the Lawrence Livermore National Laboratory (LLNL) to conduct surveys for bald eagles (Haliaeetus leucocephalus) and golden eagles (Aquila chrysaetos) at Site 300 and in the surrounding area out to 10-miles. The survey effort was intended to document the boundaries of eagle territories by careful observation of eagle behavior from selected viewing locations throughout the study area.

Blended aggregate study : final report.

DOT National Transportation Integrated Search

1980-03-01

Louisiana produces no naturally occurring skid resistant aggregate and, therefore, must import these aggregates at great expense. : In an effort to extend the yield of these aggregates, a laboratory investigation was initiated to determine the feasib...

Concrete probe-strength study : final report.

DOT National Transportation Integrated Search

1969-12-01

The Windsor probe - test system was evaluated for determining compressive strength of concrete by comparing probe strengths against cylinder and core strengths from both laboratory and field-poured concrete. Advantages and disadvantages of this syste...

Settlement study : final report.

DOT National Transportation Integrated Search

1982-09-01

This report covers field observations of several medium and high embankments' settlement along Interstate Highways 12 and 20. The predictive settlements from laboratory tests (consolidation tests) are given in an interim report published in July, 198...

Medicare program; revisions to payment policies under the physician fee schedule, clinical laboratory fee schedule & other revisions to Part B for CY 2014. Final rule with comment period.

PubMed

2013-12-10

This major final rule with comment period addresses changes to the physician fee schedule, clinical laboratory fee schedule, and other Medicare Part B payment policies to ensure that our payment systems are updated to reflect changes in medical practice and the relative value of services. This final rule with comment period also includes a discussion in the Supplementary Information regarding various programs. (See the Table of Contents for a listing of the specific issues addressed in the final rule with comment period.)

Final report on the EURAMET.M.FF-K4.2.2014 volume comparison at 100 μL—calibration of micropipettes

NASA Astrophysics Data System (ADS)

Batista, Elsa; Matus, Michael; Metaxiotou, Zoe; Tudor, Maria; Lenard, Elzbieta; Buker, Oliver; Wennergren, Per; Piluri, Erinda; Miteva, Mariana; Vicarova, Martina; Vospĕlová, Alena; Turnsek, Urska; Micic, Ljiljana; Grue, Lise-Lote; Mihailovic, Mirjana; Sarevska, Anastazija

2017-01-01

During the EURAMET TC-F meeting of 2014 and following the finalization of CCM.FF-K4.2.2011 comparison, it was agreed to start a Regional Key Comparison (KC) on volume measurements using two 100 μL micropipettes (piston pipettes) allowing the participating laboratories to assess the agreement of their results and uncertainties. Two 100 μL micropipettes were tested by 15 participants. One participant was not a member or associate member of the BIPM and was be removed from this report. The comparison started in July 2015 and ended in March 2016. The Volume and Flow Laboratory of the Portuguese Institute for Quality (IPQ) was the pilot laboratory and performed the initial and final measurements of the micropipettes. The micropipettes showed a stable volume during the whole comparison, which was confirmed by the results from the pilot laboratory. The original results of all participant NMIs were corrected to the standard atmospheric pressure in order to compare results under the same calibration conditions, and the contribution of the 'process-related handling contribution' was added to the uncertainty budget of each participant. In general the declared CMCs are in accordance with the KCDB. For the micropipette 354828Z, two laboratories had inconsistent results. For micropipette 354853Z, three laboratories had inconsistent results. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Ultra-trace analysis of 41Ca in urine by accelerator mass spectrometry: an inter-laboratory comparison

PubMed Central

Jackson, George S.; Hillegonds, Darren J.; Muzikar, Paul; Goehring, Brent

2013-01-01

A 41Ca interlaboratory comparison between Lawrence Livermore National Laboratory (LLNL) and the Purdue Rare Isotope Laboratory (PRIME Lab) has been completed. Analysis of the ratios assayed by accelerator mass spectrometry (AMS) shows that there is no statistically significant difference in the ratios. Further, Bayesian analysis shows that the uncertainties reported by both facilities are correct with the possibility of a slight under-estimation by one laboratory. Finally, the chemistry procedures used by the two facilities to produce CaF2 for the cesium sputter ion source are robust and don't yield any significant differences in the final result. PMID:24179312

Measurement of the hadronic final state in deep inelastic scattering at HERA

NASA Astrophysics Data System (ADS)

Ahmed, T.; Andreev, V.; Andrieu, B.; Arpagaus, M.; Babaev, A.; Bärwolff, H.; Bán, J.; Baranov, P.; Barrelet, E.; Bartel, W.; Bassler, U.; Beck, G. A.; Beck, H. P.; Behrend, H.-J.; Belousov, A.; Berger, Ch.; Bergstein, H.; Bernardi, G.; Bernet, R.; Berthon, U.; Bertrand-Coremans, G.; Besançon, M.; Biddulph, P.; Binder, E.; Bizot, J. C.; Blobel, V.; Borras, K.; Bosetti, P. C.; Boudry, V.; Bourdarios, C.; Brasse, F.; Braun, U.; Braunschweig, W.; Brisson, V.; Bruncko, D.; Bürger, J.; Büsser, F. W.; Buniatian, A.; Burke, S.; Buschhorn, G.; Campbell, A. J.; Carli, T.; Charles, F.; Clarke, D.; Clegg, A. B.; Colombo, M.; Coughlan, J. A.; Courau, A.; Coutures, Ch.; Cozzika, G.; Criegee, L.; Cvach, J.; Dainton, J. B.; Danilov, M.; Dann, A. W. E.; Dau, W. D.; David, M.; Deffur, E.; Delcourt, B.; Del Buono, L.; Devel, M.; De Roeck, A.; Dingus, P.; Dollfus, C.; Dowell, J. D.; Dreis, H. B.; Drescher, A.; Duboc, J.; Düllmann, D.; Dünger, O.; Duhm, H.; Eberle, M.; Ebert, J.; Ebert, T. R.; Eckerlin, G.; Efremenko, V.; Egli, S.; Eichenberger, S.; Eichler, R.; Eisele, F.; Eisenhandler, E.; Ellis, N. N.; Ellison, R. J.; Elsen, E.; Erdmann, M.; Evrard, E.; Favart, L.; Fedotov, A.; Feeken, D.; Felst, R.; Feltesse, J.; Feng, Y.; Fensome, I. F.; Ferencei, J.; Ferrarotto, F.; Flauger, W.; Fleischer, M.; Flower, P. S.; Flügge, G.; Fomenko, A.; Fominykh, B.; Forbush, M.; Formánek, J.; Foster, J. M.; Franke, G.; Fretwurst, E.; Fuhrmann, P.; Gabathuler, E.; Gamerdinger, K.; Garvey, J.; Gayler, J.; Gellrich, A.; Gennis, M.; Gensch, U.; Genzel, H.; Gerhards, R.; Gillespie, D.; Godfrey, L.; Goerlach, U.; Goerlich, L.; Goldberg, M.; Goodall, A. M.; Gorelov, I.; Goritchev, P.; Grab, C.; Grässler, H.; Grässler, R.; Greenshaw, T.; Greif, H.; Grindhammer, G.; Gruber, C.; Haack, J.; Haidt, D.; Hajduk, L.; Hamon, O.; Handschuh, D.; Hanlon, E. M.; Hapke, M.; Haries, J.; Hartz, P.; Haydar, R.; Haynes, W. J.; Heatherington, J.; Hedberg, V.; Hedgecock, R.; Heinzelmann, G.; Henderson, R. C. W.; Henschel, H.; Herma, R.; Herynek, I.; Hildesheim, W.; Hill, P.; Hilton, C. D.; Hladký, J.; Hoeger, K. C.; Huet, Ph.; Hufnagel, H.; Huot, N.; Ibbotson, M.; Jabiol, M. A.; Jacholkowska, A.; Jacobsson, C.; Jaffre, M.; Jöhnsson, L.; Johannsen, K.; Johnson, D. P.; Johnson, L.; Jung, H.; Kalmus, P. I. P.; Kasarian, S.; Kaschowitz, R.; Kasselmann, P.; Kathage, U.; Kaufmann, H. H.; Kenyon, I. R.; Kermiche, S.; Kiesling, C.; Klein, M.; Kleinwort, C.; Knies, G.; Köhler, T.; Kolanoski, H.; Kole, F.; Kolya, S. D.; Korbel, V.; Korn, M.; Kostka, P.; Kotelnikov, S. K.; Krasny, M. W.; Krehbiel, H.; Krücker, D.; Krüger, U.; Kubenka, J. P.; Küster, H.; Kuhlen, M.; Kurça, T.; Kurzhöfer, J.; Kuznik, B.; Lander, R.; London, M. P. J.; Langkau, R.; Lanius, P.; Laporte, J. F.; Lebedev, A.; Lebedev, A.; Leuschner, A.; Leverenz, C.; Levin, D.; Levonian, S.; Ley, Ch.; Lindner, A.; Lindström, G.; Loch, P.; Lohmander, H.; Lopez, G. C.; Lüers, D.; Magnussen, N.; Malinovski, E.; Mani, S.; Marage, P.; Marks, J.; Marshall, R.; Martens, J.; Martin, R.; Martyn, H.-U.; Martyniak, J.; Masson, S.; Mavroidis, A.; Maxfield, S. J.; McMahon, S. J.; Mehta, A.; Meier, K.; Merz, T.; Meyer, C. A.; Meyer, H.; Meyer, J.; Mikocki, S.; Milone, V.; Monnier, E.; Moreau, F.; Moreels, J.; Morris, J. V.; Morton, J. M.; Müller, K.; Murín, P.; Murray, S. A.; Nagovizin, V.; Naroska, B.; Naumann, Th.; Newton, D.; Nguyen, H. K.; Niebergall, F.; Nisius, R.; Nowak, G.; Noyes, G. W.; Nyberg, M.; Oberlack, H.; Obrock, U.; Olsson, J. E.; Orenstein, S.; Ould-Saada, F.; Pascaud, C.; Patel, G. D.; Peppel, E.; Peters, S.; Phillips, H. T.; Phillips, J. P.; Pichler, Ch.; Pilgram, W.; Pitzl, D.; Prosi, R.; Raupach, F.; Rauschnabel, K.; Reimer, P.; Ribarics, P.; Riech, V.; Riedlberger, J.; Rietz, M.; Robertson, S. M.; Robmann, P.; Roosen, R.; Rostovtsev, A.; Royon, C.; Rudowicz, M.; Ruffer, M.; Rusakov, S.; Rybicki, K.; Ryseck, E.; Sacton, J.; Sahlmann, N.; Sanchez, E.; Sankey, D. P. C.; Savitsky, M.; Schacht, P.; Schleper, P.; von Schlippe, W.; Schmidt, C.; Schmidt, D.; Schmitz, W.; Schröder, V.; Schulz, M.; Schwind, A.; Scobel, W.; Seehausen, U.; Sell, R.; Seman, M.; Semenov, A.; Shekelyan, V.; Sheviakov, I.; Shooshtari, H.; Siegmon, G.; Siewert, U.; Sirois, Y.; Skillicorn, I. O.; Smirnov, P.; Smith, J. R.; Smolik, L.; Soloviev, Y.; Spitzer, H.; Staroba, P.; Steenbock, M.; Steffen, P.; Steinberg, R.; Steiner, H.; Stella, B.; Stephens, K.; Stier, J.; Strachota, J.; Straumann, U.; Struczinski, W.; Sutton, J. P.; Taylor, R. E.; Thompson, G.; Thompson, R. J.; Tichomirov, I.; Trenkel, C.; Truöl, P.; Tchernyshov, V.; Turnau, J.; Tutas, J.; Urban, L.; Usik, A.; Valkar, S.; Valkarova, A.; Vallee, C.; Van Esch, P.; Vartapetian, A.; Vazdik, Y.; Vecko, M.; Verrecchia, P.; Vick, R.; Villet, G.; Vogel, E.; Wacker, K.; Walker, I. W.; Walther, A.; Weber, G.; Wegener, D.; Wegner, A.; Wellisch, H. P.; Willard, S.; Winde, M.; Winter, G.-G.; Wolff, Th.; Womersley, L. A.; Wright, A. E.; Wulff, N.; Yiou, T. P.; Ząçek, J.; Závada, P.; Zeitnitz, C.; Ziaeepour, H.; Zimmer, M.; Zimmermann, W.; Zomer, F.; H1 Collaboration

1993-01-01

We report on the first experimental study of the hadronic final state in deep inelastic electron-proton scattering with the H1 detector at HERA. Energy flow and transverse momentum characteristics are measured and presented both in the laboratory and in the hadronic center of mass frames. Comparison is made with QCD models distinguished by their different treatment of parton emission.

Fifty Years of Progress, 1937-1987 [Lawrence Berkeley Laboratory (LBL, LBNL)

DOE R&D Accomplishments Database

Budinger, T. F. (ed.)

1987-01-01

This booklet was prepared for the 50th anniversary of medical and biological research at the Donner Laboratory and the Lawrence Berkeley Laboratory of the University of California. The intent is to present historical facts and to highlight important facets of fifty years of accomplishments in medical and biological sciences. A list of selected scientific publications from 1937 to 1960 is included to demonstrate the character and lasting importance of early pioneering work. The organizational concept is to show the research themes starting with the history, then discoveries of medically important radionuclides, then the use of accelerated charged particles in therapy, next human physiology studies then sequentially studies of biology from tissues to macromolecules; and finally studies of the genetic code.

Computation in the Wild: Moving Beyond the Metaphor

DTIC Science & Technology

2006-03-01

AFRL-IF-RS-TR-2006-105 Final Technical Report March 2006 COMPUTATION IN THE WILD: MOVING BEYOND THE METAPHOR University...Government. AIR FORCE RESEARCH LABORATORY INFORMATION DIRECTORATE ROME RESEARCH SITE ROME, NEW YORK STINFO FINAL REPORT This... report has been reviewed by the Air Force Research Laboratory, Information Directorate, Public Affairs Office (IFOIPA) and is releasable to the National

Final report on comparison of hydraulic pressure balance effective area determination in the range up to 80 MPa

NASA Astrophysics Data System (ADS)

Grgec Bermanec, L.; Pantic, D.; Ramac, B.

2018-01-01

Bilateral comparison was organized between the laboratory for process measurement of the Croatian Metrology Institute (HMI/FSB-LPM) and the pressure laboratory of the Directorate of Measures and Precious Metals of the Republic of Serbia (DMDM). Laboratory for process measurement of HMI acted as the pilot laboratory. The aim of the comparison was to evaluate the degree of equivalence in the determination of effective area and elastic distortion coefficient, considering respective uncertainties of the two laboratories. Measurements were done on the pressure balance in gauge mode, with oil as transmitting medium, in the gauge pressure range 10–80 MPa. The results of the comparison successfully demonstrated that the hydraulic gauge pressure standards are equivalent within their claimed uncertainties. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Cleaning Aged EPDM Rubber Roofing Membrane Material for Patching: Laboratory Investigations and Recommendations

DTIC Science & Technology

1992-08-01

Cleaning Aged EPDM Rubber Roofing Membrane Material for Patching: Laboratory Investigations and Recommendations Walter J. Rossiter, Jr. T N n-’T ic...condition of the aged EPDM rubber before bonding. This study assessed the effectiveness of different cleaning methods for preparing aged EPDM membranes for...REPORT DATE 3. REPORT TYPE AND DATES COVERED August 1992 Final 4. TITLE AND SUBTITLE 5. FUNDING NUMBERS Cleaning Aged EPDM Rubber Roofing Membrane

Consumable and Refundable Supplies Items for Production Agriculture Mechanics Laboratories as Influenced by Selected Characteristics of Vocational Agriculture Program and Teacher. Final Report.

ERIC Educational Resources Information Center

Gerstenlauer, David L.

This study was conducted to develop a list of basic consumable and refundable supplies to be used in a secondary agricultural production mechanics laboratory program in Pennsylvania. A total of 72 surveys were sent to selected teachers: 24 in the area of woodworking, 24 in the area of metal working, and 24 covering all other areas of agricultural…

Final Technical Report: Magnetic Reconnection in High-Energy Laser-Produced Plasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Germaschewski, Kai; Fox, William; Bhattacharjee, Amitava

This report describes the final results from the DOE Grant DE-SC0007168, “Fast Magnetic Reconnection in HED Laser-Produced Plasmas.” The recent generation of laboratory high-energy-density physics facilities has opened significant physics opportunities for experimentally modeling astrophysical plasmas. The goal of this proposal is to use these new tools to study fundamental problems in plasma physics and plasma astrophysics. Fundamental topics in this area involve study of the generation, amplification, and fate of magnetic fields, which are observed to pervade the plasma universe and govern its evolution. This project combined experiments at DOE laser facilities with kinetic plasma simulation to study thesemore » processes. The primary original goal of the project was to study magnetic reconnection using a new experimental platform, colliding magnetized laser-produced plasmas. However through a series of fortuitous discoveries, the work broadened out to allow significant advancement on multiple topics in laboratory astrophysics, including magnetic reconnection, Weibel instability, and collisionless shocks.« less

Web-Based Evaluation System for a Problem-Based Laboratory

ERIC Educational Resources Information Center

Azli, Naziha Ahmadi; Othman, Mohd Shahizan

2008-01-01

The Faculty of Electrical Engineering, University Technology Malaysia is currently moving towards a Problem-Based Laboratory implementation rather than the conventional instructional-based laboratory for final year students. The laboratory has commenced session with about 500 students' registration in the 2007/08/1. The Problem-Based Laboratory…

Modeling Drift Compression in an Integrated Beam Experiment for Heavy-Ion-Fusion

NASA Astrophysics Data System (ADS)

Sharp, W. M.; Barnard, J. J.; Friedman, A.; Grote, D. P.; Celata, C. M.; Yu, S. S.

2003-10-01

The Integrated Beam Experiment (IBX) is an induction accelerator being designed to further develop the science base for heavy-ion fusion. The experiment is being developed jointly by Lawrence Berkeley National Laboratory, Lawrence Livermore National Laboratory, and Princeton Plasma Physics Laboratory. One conceptual approach would first accelerate a 0.5-1 A beam of singly charged potassium ions to 5 MeV, impose a head-to-tail velocity tilt to compress the beam longitudinally, and finally focus the beam radiallly using a series of quadrupole lenses. The lengthwise compression is a critical step because the radial size must be controlled as the current increases, and the beam emittance must be kept minimal. The work reported here first uses the moment-based model HERMES to design the drift-compression beam line and to assess the sensitivity of the final beam profile to beam and lattice errors. The particle-in-cell code WARP is then used to validate the physics design, study the phase-space evolution, and quantify the emittance growth.

Glucose-6-phosphate dehydrogenase laboratory assay: How, when, and why?

PubMed

Minucci, Angelo; Giardina, Bruno; Zuppi, Cecilia; Capoluongo, Ettore

2009-01-01

Glucose 6-phosphate dehydrogenase (G6PD) deficiency is the most common defect of red blood cells. Although some different laboratory techniques or methods are employed for the biochemical screening, a strict relationship between biochemists, clinicians, and molecular biologists is necessary for a definitive diagnosis. This article represents an overview on the current laboratory tests finalized to the screening or to the definitive diagnosis of G6PD-deficiency, underlying the problems regarding the biochemical and molecular identification of heterozygote females other than those regarding the standardization of the clinical and laboratory diagnostic procedures. Finally, this review is aimed to give a flow-chart for the complete diagnostic approach of G6PD-deficiency.

J. Robert Schrieffer and the BCS Theory of Superconductivity

Science.gov Websites

and a chief scientist at the National High Magnetic Field Laboratory before his retirement in 2006 Theoretical Studies of Magnetic Systems. Final Report, August 1, 1994 - November 30, 1997, DOE Technical

The effects of napping on night shift performance : final report.

DOT National Transportation Integrated Search

2000-02-01

This study represents a collaborative effort between the Federal Aviation Administrations Civil Aeromedical Institute and the US Army Aeromedical Research Laboratory to investigate the effects of napping on the midnight shift as a potential counte...

40 CFR 160.185 - Reporting of study results.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Reporting of study results. 160.185... GOOD LABORATORY PRACTICE STANDARDS Records and Reports § 160.185 Reporting of study results. (a) A final report shall be prepared for each study and shall include, but not necessarily be limited to, the...

40 CFR 160.185 - Reporting of study results.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Reporting of study results. 160.185... GOOD LABORATORY PRACTICE STANDARDS Records and Reports § 160.185 Reporting of study results. (a) A final report shall be prepared for each study and shall include, but not necessarily be limited to, the...

Laboratory Investigations of Stratospheric Halogen Chemistry

NASA Technical Reports Server (NTRS)

Wine, Paul H.; Nicovich, J. Michael; Stickel, Robert E.; Hynes, Anthony J.

1997-01-01

A final report for the NASA-supported project on laboratory investigations of stratospheric halogen chemistry is presented. In recent years, this project has focused on three areas of research: (1) kinetic, mechanistic, and thermochemical studies of reactions which produce weakly bound chemical species of atmospheric interest; (2) development of flash photolysis schemes for studying radical-radical reactions of stratospheric interest; and (3) photochemistry studies of interest for understanding stratospheric chemistry. The first section of this paper contains a discussion of work which has not yet been published. All subsequent chapters contain reprints of published papers that acknowledge support from this grant.

Standards Applicable to Generators of Hazardous Waste; Alternative Requirements for Hazardous Waste Determination and Accumulation of Unwanted Material at Laboratories Owned by Colleges and Universities and Other Eligible Academic Entities Formally Affiliated With Colleges and Universities. Final Rule. Federal Register, Environmental Protection Agency. 40 CFR Parts 261 and 262. Part II

ERIC Educational Resources Information Center

National Archives and Records Administration, 2008

2008-01-01

The Environmental Protection Agency (EPA or the Agency) is finalizing an alternative set of generator requirements applicable to laboratories owned by eligible academic entities, as defined in this final rule. The rule provides a flexible and protective set of regulations that address the specific nature of hazardous waste generation and…

Fly ash in concrete : final report.

DOT National Transportation Integrated Search

1990-08-01

This study was initiated to develop information regarding the use of fly ash in portland cement concrete for state construction projects. : Concrete mixes containing 10%, 20%, 30%, 40% and 60% fly ash were evaluated in the laboratory in combination w...

Internally sealed concrete for bridge deck protection : final report.

DOT National Transportation Integrated Search

1983-01-01

This study investigated the characteristics of internally sealed concrete through tests on specimens fabricated in the laboratory to determine its properties and an installation in a bridge deck to assess the controls needed during construction and i...

DHM and serious games: a case-study oil and gas laboratories.

PubMed

Santos, V; Zamberlan, M; Streit, P; Oliveira, J; Guimarães, C; Pastura, F; Cid, G

2012-01-01

The aim in this paper is to present a research on the application of serious games for the design of laboratories in the oil and gas industries. The focus is in human virtual representation acquired from 3D scanning, human interaction, workspace layout and equipment designed considering ergonomics standards. The laboratory studies were simulated in Unity3D platform, which allows the users to control the DHM1 on the dynamic virtual scenario, in order to simulate work activities. This methodology can change the design process by improving the level of interaction between final users, managers and human factor teams. That helps to better visualize future work settings and improve the level of participation between all stakeholders.

The effects of supplemental online learning aids on student performance and student engagement in Medical Microbiology

NASA Astrophysics Data System (ADS)

Murray, Kimberly

The purpose of this study was to determine the effects of online learning aids on student performance and engagement. The thirty-five participants of the current study were students enrolled in two sections of a junior level Medical Microbiology laboratory. The experimental section was required to spend ten minutes each week on an online learning aid. The online program, StudyMate(TM), was used to present text and images in the form of flash cards, multiple choice questions, matching, and crossword puzzles. Both groups completed the Index of Learning Style survey, an initial engagement survey at the start of the course, and a final engagement survey at the end of the course. Statistical analysis showed no significant differences between the groups at the start of the course or after the course was completed for learning style, science grade point average, overall grade point average, initial engagement or final engagement. A moderate correlation was found between microbiology course and laboratory grades and a reflective learning style.

SUPERFUND TREATABILITY CLEARINGHOUSE: FINAL REPORT: DEVELOPMENT OF OPTIMUM TREATMENT SYSTEM FOR WASTEWATER LAGOONS PHASE II - SOLVENT EXTRACTION LABORATORY TESTING

EPA Science Inventory

The U.S. Army surveyed innovative treatment techniques for restoration of hazardous waste lagoons and selected solvent extraction as cost-effective restoration for further study. This treatability study focuses on treatment of organic (explosive) contaminated lagoon sediments w...

A single dose of alcohol does not meaningfully alter circadian phase advances and phase delays to light in humans

PubMed Central

Rizvydeen, Muneer; Fogg, Louis F.; Keshavarzian, Ali

2016-01-01

Central circadian timing influences mental and physical health. Research in nocturnal rodents has demonstrated that when alcohol is consumed, it reaches the central hypothalamic circadian pacemaker (suprachiasmatic nuclei) and can directly alter circadian phase shifts to light. In two separate studies, we examined, for the first time, the effects of a single dose of alcohol on circadian phase advances and phase delays to light in humans. Two 23-day within-subjects placebo-controlled counterbalanced design studies were conducted. Both studies consisted of 6 days of fixed baseline sleep to stabilize circadian timing, a 2-day laboratory session, a 6-day break, and a repeat of 6 days of fixed sleep and a 2-day laboratory session. In the phase advance study (n = 10 light drinkers, 24–45 yr), the laboratory sessions consisted of a baseline dim light phase assessment, sleep episode, alcohol (0.6 g/kg) or placebo, 2-h morning bright light pulse, and final phase assessment. In the phase-delay study (n = 14 light drinkers, 22–44 yr), the laboratory sessions consisted of a baseline phase assessment, alcohol (0.8 g/kg) or placebo, 2-h late night bright light pulse, sleep episode, and final phase assessment. In both studies, alcohol either increased or decreased the observed phase shifts to light (interaction P ≥ 0.46), but the effect of alcohol vs. placebo on phase shifts to light was always on average smaller than 30 min. Thus, no meaningful effects of a single dose of alcohol vs. placebo on circadian phase shifts to light in humans were observed. PMID:26936778

A single dose of alcohol does not meaningfully alter circadian phase advances and phase delays to light in humans.

PubMed

Burgess, Helen J; Rizvydeen, Muneer; Fogg, Louis F; Keshavarzian, Ali

2016-04-15

Central circadian timing influences mental and physical health. Research in nocturnal rodents has demonstrated that when alcohol is consumed, it reaches the central hypothalamic circadian pacemaker (suprachiasmatic nuclei) and can directly alter circadian phase shifts to light. In two separate studies, we examined, for the first time, the effects of a single dose of alcohol on circadian phase advances and phase delays to light in humans. Two 23-day within-subjects placebo-controlled counterbalanced design studies were conducted. Both studies consisted of 6 days of fixed baseline sleep to stabilize circadian timing, a 2-day laboratory session, a 6-day break, and a repeat of 6 days of fixed sleep and a 2-day laboratory session. In the phase advance study (n= 10 light drinkers, 24-45 yr), the laboratory sessions consisted of a baseline dim light phase assessment, sleep episode, alcohol (0.6 g/kg) or placebo, 2-h morning bright light pulse, and final phase assessment. In the phase-delay study (n= 14 light drinkers, 22-44 yr), the laboratory sessions consisted of a baseline phase assessment, alcohol (0.8 g/kg) or placebo, 2-h late night bright light pulse, sleep episode, and final phase assessment. In both studies, alcohol either increased or decreased the observed phase shifts to light (interaction P≥ 0.46), but the effect of alcohol vs. placebo on phase shifts to light was always on average smaller than 30 min. Thus, no meaningful effects of a single dose of alcohol vs. placebo on circadian phase shifts to light in humans were observed. Copyright © 2016 the American Physiological Society.

[Activities of Colorado University

NASA Technical Reports Server (NTRS)

Snow, Theodore P.; Bierbaum, Veronica

2003-01-01

During the report period we completed several studies and embarked on a new set of laboratory experiments. We also hired a new post-doctoral Research Associate, Momir Stepanovic, who has gradually assumed leadership in the laboratory work. The other person involved has been graduate student Brian Eichelberger, who will complete his Ph.D. based on this work by late spring of this year. We have also continued to collaborate with our previous postdoctoral Research Associate, Valery Le Page, through a consulting arrangement. In the following sections we summarize work that has been completed and either in print, in press, or in final stages of preparation for publication; current work being carried out in the laboratory; and plans for the coming year. Work completed in 2002: 1. Modeling the physical and chemical states of PAHs in the diffuse interstellar medium. 2. Hydrogenation and charge states of polycyclic aromatic hydrocarbons in diffuse clouds. 3. Laboratory studies of chemical reactions involving carbon chain anions.

The Influence of Laboratory Instruction on Science Achievement and Attitude Toward Science across Gender Differences

NASA Astrophysics Data System (ADS)

Freedman, Michael P.

This study investigated the use of a hands-on laboratory program to improve attitudes toward science and increase achievement levels in science knowledge among students in a ninth grade physical science course. An objective final examination measured achievement in science knowledge, and a Q sort survey measured attitude toward science. A t test compared the groups' differences in achievement and attitude toward science. An analysis of covariance determined the effect of the laboratory treatment on the dependent variable, with attitude toward science as the covariable. The findings showed that students with regular laboratory instruction scored significantly higher (p < .05) on achievement in science knowledge than those without laboratory instruction, girls with regular laboratory instruction scored significantly higher (p < .05) on achievement in science knowledge than those without laboratory instruction, and girls and boys within the treatment group did not differ significantly on achievement in science knowledge. No significant differences were reported in attitude toward science between or within groups.

Body fluid analysis: clinical utility and applicability of published studies to guide interpretation of today's laboratory testing in serous fluids.

PubMed

Block, Darci R; Algeciras-Schimnich, Alicia

2013-01-01

Requests for testing various analytes in serous fluids (e.g., pleural, peritoneal, pericardial effusions) are submitted daily to clinical laboratories. Testing of these fluids deviates from assay manufacturers' specifications, as most laboratory assays are optimized for testing blood or urine specimens. These requests add a burden to clinical laboratories, which need to validate assay performance characteristics in these fluids to exclude matrix interferences (given the different composition of body fluids) while maintaining regulatory compliance. Body fluid testing for a number of analytes has been reported in the literature; however, understanding the clinical utility of these analytes is critical because laboratories must address the analytic and clinical validation requirements, while educating clinicians on proper test utilization. In this article, we review the published data to evaluate the clinical utility of testing for numerous analytes in body fluid specimens. We also highlight the pre-analytic and analytic variables that need to be considered when reviewing published studies in body fluid testing. Finally, we provide guidance on how published studies might (or might not) guide interpretation of test results in today's clinical laboratories.

KEY COMPARISON: Final report of comparison of the calibrations of hydrometers for liquid density determination between SIM laboratories: SIM.M.D-K4

NASA Astrophysics Data System (ADS)

Becerra, Luis Omar

2009-01-01

This SIM comparison on the calibration of high accuracy hydrometers was carried out within fourteen laboratories in the density range from 600 kg/m3 to 1300 kg/m3 in order to evaluate the degree of equivalence among participant laboratories. This key comparison anticipates the planned key comparison CCM.D-K4, and is intended to be linked with CCM.D-K4 when results are available. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).

Summer Research Program (1992). Summer Faculty Research Program (SFRP) Reports. Volume 3. Phillips Laboratory.

DTIC Science & Technology

1992-12-28

Phillips Laboratory Kirtland Air Force Base NM 87117-6008 Sponsored by: Air Force Office of Scientific Research Bolling Air Force Base...Zindel, D.: 1963, Z. Astrophys. 57, 82. 29-13 FINAL REPORT SUMMER FACULTY RESEARCH PROGRAM AT PHILLIPS LABORATORY KIRTLAND AIR FORCE BASE...Program Phillips Laboratory Sponsored by: Air Force Office of Scientific

The Curriculum Development Project for the Medical Laboratory Technology Program at Miami-Dade Junior College, Miami, Florida. Final Report.

ERIC Educational Resources Information Center

Miami-Dade Junior Coll., FL. Div. of Allied Health Studies.

During Phase I of an Allied Health Professions Basic Improvement Grant, a five-member committee developed a curriculum for a medical laboratory technology program at Miami-Dade Junior College by: (1) defining competencies which differentiate a certified laboratory assistant from a medical laboratory technician, (2) translating expected laboratory…

Preliminary investigation of RAP and RAS in HMAC : final report, February 2010.

DOT National Transportation Integrated Search

2010-02-01

A laboratory study was undertaken to investigate how various proportions of reclaimed asphalt pavement (RAP) and reclaimed asphalt shingles (RAS) added to hot mixed asphalt concrete (HMAC) mixtures affect the Superpave performance grade of the blende...

Laboratory correlation of soil swell potential : final report.

DOT National Transportation Integrated Search

1979-03-01

The objective of the study was to determine if a correlation exists between the Potential Volume Change Test and the Potential Vertical Rise Test as compared to the Third Cycle Expansion Pressure Test. In order to accomplish this objective, samples o...

Evaluation of corrosion inhibitor : final report.

DOT National Transportation Integrated Search

1980-05-01

Solution to the problem of deterioration of bridge decks due to the corrosion of embedded steel has been sought by engineers for a long time. The purpose of the study was to evaluate, under laboratory conditions, the properties of concrete using a co...

Evaluation of an asphalt-treated drainage blanket in a rigid pavement section : final report.

DOT National Transportation Integrated Search

1978-01-01

This study was undertaken to develop a permeable yet stable, asphalt-treated, layered shoulder drainage system for a typical pavement section. Stability and permeability characteristics of several mixes were evaluated in the laboratory. Two installat...

Special Education Teacher Computer Literacy Training. Project STEEL. A Special Project To Develop and Implement a Computer-Based Special Teacher Education and Evaluation Laboratory. Volume II. Final Report.

ERIC Educational Resources Information Center

Frick, Theodore W.; And Others

The document is part of the final report on Project STEEL (Special Teacher Education and Evaluation Laboratory) intended to extend the utilization of technology in the training of preservice special education teachers. This volume focuses on the second of four project objectives, the development of a special education teacher computer literacy…

Final report on key comparison CCAUV.A-K5: pressure calibration of laboratory standard microphones in the frequency range 2 Hz to 10 kHz

NASA Astrophysics Data System (ADS)

Avison, Janine; Barham, Richard

2014-01-01

This document and the accompanying spreadsheets constitute the final report for key comparison CCAUV.A-K5 on the pressure calibration of laboratory standard microphones in the frequency range from 2 Hz to 10 kHz. Twelve national measurement institutes took part in the key comparison and the National Physical Laboratory piloted the project. Two laboratory standard microphones IEC type LS1P were circulated to the participants and results in the form of regular calibration certificates were collected throughout the project. One of the microphones was subsequently deemed to have compromised stability for the purpose of deriving a reference value. Consequently the key comparison reference value (KCRV) has been made based on the weighted mean results for sensitivity level and for sensitivity phase from just one of the microphones. Corresponding degrees of equivalence (DoEs) have also been calculated and are presented. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCAUV, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Task Order 7. Use of activated carbon for treatment of explosives-contaminated groundwater at the Milan Army Ammunition Plant (MAAP). Final report, Apr 89-May 90

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dennis, R.M.; Wujcik, W.J.; Lowe, W.L.

1990-05-01

The primary objective of this task was to determine the feasibility of using GAC to treat ground water contaminated by explosives at the Milan Army Ammunition Plant (MAAP) in Milan, Tennessee. Laboratory GAC isotherm studies were conducted and two carbons, Atochem, Inc. GAC 830 and Calgon Filtrasorb 300, were selected for further testing in continuous flow GAC columns. Three pilot scale continuous flow GAC column tests were performed at MAAP using the two carbons selected from the laboratory GAC isotherm studies. The results from the laboratory and pilot studies are presented in this report. They show that concurrent removal ofmore » explosives such as TNT, RDX, HMX, Tetryl, and nitrobenzenes from ground water using continuous flow granular activated carbon is feasible.« less

Life sciences payload definition and integration study. Volume 1: Executive summary. [carry-on laboratory for Spacelab

NASA Technical Reports Server (NTRS)

1974-01-01

The definition and integration tasks involved in the development of design concepts for a carry-on laboratory (COL), to be compatible with Spacelab operations, were divided into the following study areas: (1) identification of research and equipment requirements of the COL; (2) development of a number of conceptual layouts for COL based on the defined research of final conceptual designs; and (4) development of COL planning information for definition of COL/Spacelab interface data, cost data, and program cost schedules, including design drawings of a selected COL to permit fabrication of a functional breadboard.

Compact acoustic levitation device for studies in fluid dynamics and material science in the laboratory and microgravity

NASA Technical Reports Server (NTRS)

Trinh, E. H.

1985-01-01

An ultrasonic levitation device operable in both ordinary ground-based as well as in potential space-borne laboratories is described together with its various applications in the fields of fluid dynamics, material science, and light scattering. Some of the phenomena which can be studied by this instrument include surface waves on freely suspended liquids, the variations of the surface tension with temperature and contamination, the deep undercooling of materials with the temperature variations of their density and viscosity, and finally some of the optical diffraction properties of transparent substances.

Phase B - final definition and preliminary design study for the initial Atmospheric Cloud Physics Laboratory (ACPL): A spacelab mission payload. Work breakdown structure for phase C/D DR-MA-06 (preliminary issue)

NASA Technical Reports Server (NTRS)

1976-01-01

The Work Breakdown Structure (WBS) and Dictionary (DR-MA-06) for initial and subsequent flights of the Atmospheric Cloud Physics Laboratory (ACPL) is presented. An attempt is made to identify specific equipment and components in each of the eleven subsystems; they are listed under the appropriate subdivisions of the WBS. The reader is cautioned that some of these components are likely to change substantially during the course of the study, and the list provided should only be considered representative.

The National Program of Educational Laboratories. Final Report.

ERIC Educational Resources Information Center

Chase, Francis S.

This report presents results of a critical analysis of 20 regional educational laboratories and nine university research and development centers established under ESEA Title IV. Observations, supported by specific examples, are made concerning the laboratories and centers and deal with their roles, programs definitions, impact on educational…

Clinical, biochemical and genetic features with nonclassical 21-hydroxylase deficiency and final height.

PubMed

Savaş-Erdeve, Şenay; Çetinkaya, Semra; Abalı, Zehra Yavaş; Poyrazoğlu, Şükran; Baş, Firdevs; Berberoğlu, Merih; Sıklar, Zeynep; Korkmaz, Özlem; Buluş, Derya; Akbaş, Emine Demet; Güran, Tülay; Böber, Ece; Akın, Onur; Yılmaz, Gülay Can; Aycan, Zehra

2017-07-26

The clinical, laboratory, genetic properties and final height of a large cohort of patients with nonclassical 21-hydroxylase deficiency (NC21OHD) in Turkey were analyzed. This multicenter, nationwide web-based study collected data. The mean age was 9.79±4.35 years (229 girls, 29 boys). The most common symptoms were premature pubarche (54.6%) and hirsutism (28.6%). The peak cortisol was found below 18 μg/dL in three (15.45%) patients. A mutation was detected in the CYP21A2 gene of 182 (87.5%) patients. The most common mutation was V281L. Final height in female patients who were diagnosed and treated before attaining final height or near final height was found to be shorter than the final height in female patients who were diagnosed after attaining final height or near final height. The final height of the patients who were treated during childhood was found to be shorter than the final height of patients during the adolescent period.

HYPOPHOSPHATEMIC RICKETS: CASE REPORT.

PubMed

Maia, Marta Liliane de Almeida; Abreu, Ana Lucia Santos; Nogueira, Paulo Cesar Koch; Val, Maria Luiza Dautro Moreira do; Carvalhaes, João Tomas de Abreu; Andrade, Maria Cristina de

2018-03-29

Early diagnosis and immediate treatment of hypophosphatemic rickets is of utmost importance as it may prevent subsequent sequelae. This report aims at warning pediatricians to consider the presence of the disease. Description of the metabolic profile, creatinine clearance, nutritional status, weight and body structure of a patient who presented the clinical-laboratorial characteristics of hypophosphatemic rickets and was followed in an outpatient clinic for tubulopathies over the period of 12 months. The patient had been bedridden for some time, was dependent on mechanical ventilation and presented an altered metabolic bone condition. Treatment was phosphate (initial: 65 mg/kg/day and final: 24,2 mg/kg/day), calcium (initial: 127 mg/kg/day, final: 48,4 mg/kg/day) and calcitriol (initial: 0.06 mcg/kg/day, final: 0.03 mcg/kg/day). The patient improved, evolving into spontaneous breathing and walking unaided. Laboratory results: calcium (mg/dL) initial 7.1, final 10.1; phosphate (mg/dL) initial 1.7 final 3.2; magnesium (mg/dL) initial 1.5 final 2.1, parathyroid hormone (pg/l) initial 85.8, final 52.7, alkaline phosphatase (UI/l) initial 12660, final 938; there was also improvement in weight/structural development (Z score: H/A initial: -6.05, final -3.64; W/A: initial -2.92, final -1.57) with presence of transitory gallstones. Creatinine clearance (mL/min/1.73m2bsa) was constant. The medication improved his laboratory results and nutritional status, but the patient did not return for two years for follow-up and, during this period, his condition has noticeably deteriorated. Early diagnosis and follow-up are essential in dealing with this pathology.

A laboratory comparison of clockwise and counter-clockwise rapidly rotating shift schedules, part II : performance : final report.

DOT National Transportation Integrated Search

2002-07-01

INTRODUCTION. Many Air Traffic Control Specialists (ATCSs) work a relatively unique counter-clockwise, rapidly rotating shift schedule. Although arguments against these kinds of schedules are prevalent in the literature, few studies have examined rot...

Design and evaluation of high strength concrete for girders : final report.

DOT National Transportation Integrated Search

1980-05-01

The scope of the study was to make concrete mixes in the laboratory using a partial factorial, with three cement contents, two coarse aggregates and three fine-to-coarse aggregate ratios. The mixes showing the best properties and highest compressive ...

40 CFR 160.35 - Quality assurance unit.

Code of Federal Regulations, 2012 CFR

2012-07-01

... standard operating procedures were made without proper authorization and documentation. (6) Review the final study report to assure that such report accurately describes the methods and standard operating... LABORATORY PRACTICE STANDARDS Organization and Personnel § 160.35 Quality assurance unit. (a) A testing...

40 CFR 160.35 - Quality assurance unit.

Code of Federal Regulations, 2010 CFR

2010-07-01

... standard operating procedures were made without proper authorization and documentation. (6) Review the final study report to assure that such report accurately describes the methods and standard operating... LABORATORY PRACTICE STANDARDS Organization and Personnel § 160.35 Quality assurance unit. (a) A testing...

40 CFR 160.35 - Quality assurance unit.

Code of Federal Regulations, 2014 CFR

2014-07-01

... standard operating procedures were made without proper authorization and documentation. (6) Review the final study report to assure that such report accurately describes the methods and standard operating... LABORATORY PRACTICE STANDARDS Organization and Personnel § 160.35 Quality assurance unit. (a) A testing...

40 CFR 160.35 - Quality assurance unit.

Code of Federal Regulations, 2013 CFR

2013-07-01

... standard operating procedures were made without proper authorization and documentation. (6) Review the final study report to assure that such report accurately describes the methods and standard operating... LABORATORY PRACTICE STANDARDS Organization and Personnel § 160.35 Quality assurance unit. (a) A testing...

40 CFR 160.35 - Quality assurance unit.

Code of Federal Regulations, 2011 CFR

2011-07-01

... standard operating procedures were made without proper authorization and documentation. (6) Review the final study report to assure that such report accurately describes the methods and standard operating... LABORATORY PRACTICE STANDARDS Organization and Personnel § 160.35 Quality assurance unit. (a) A testing...

ICASE Semiannual Report

DTIC Science & Technology

1991-05-01

Greenberg and B. Lubachevsky (AT& T, Bell Laboratories). We have developed algorithms suitable for simulating a general class of stack replacement policy al...systems of conservation laws. Finally, we began to study various edge detectors based on the (truncated) Hilbert trans- form, in the context of spectral

Results of an inter and intra laboratory exercise on the assessment of complex autosomal DNA profiles.

PubMed

Benschop, Corina C G; Connolly, Edward; Ansell, Ricky; Kokshoorn, Bas

2017-01-01

The interpretation of complex DNA profiles may differ between laboratories and reporting officers, which can lead to discrepancies in the final reports. In this study, we assessed the intra and inter laboratory variation in DNA mixture interpretation for three European ISO17025-accredited laboratories. To this aim, 26 reporting officers analyzed five sets of DNA profiles. Three main aspects were considered: 1) whether the mixed DNA profiles met the criteria for comparison to a reference profile, 2) the actual result of the comparison between references and DNA profiling data and 3) whether the weight of the DNA evidence could be assessed. Similarity in answers depended mostly on the complexity of the tasks. This study showed less variation within laboratories than between laboratories which could be the result of differences between internal laboratory guidelines and methods and tools available. Results show the profile types for which the three laboratories report differently, which informs indirectly on the complexity threshold the laboratories employ. Largest differences between laboratories were caused by the methods available to assess the weight of the DNA evidence. This exercise aids in training forensic scientists, refining laboratory guidelines and explaining differences between laboratories in court. Undertaking more collaborative exercises in future may stimulate dialog and consensus regarding interpretation. For training purposes, DNA profiles of the mixed stains and questioned references are made available. Copyright © 2016 The Chartered Society of Forensic Sciences. Published by Elsevier Ireland Ltd. All rights reserved.

Final report of EURAMET 1197: Supplementary bilateral comparison of hydraulic gauge pressure standards up to 50 MPa

NASA Astrophysics Data System (ADS)

Durgut, Yasin; Petrovski, Nenad; Kacarski, Vanco

2012-01-01

Interlaboratory comparisons are important for the laboratories to assess their own measurement capability. It is equally important for the accreditation bodies and assessors during the audit process of a laboratory to judge whether the laboratory is doing well. As per accreditation rules, it is mandatory for the testing and calibration laboratories to participate in such comparisons from time to time. In this report, results of the bilateral interlaboratory comparison in pressure area in hydraulic media up to 50 MPa gauge between UME (Turkey) and BOM (The FYR of Macedonia) are presented. The artefact used for the comparison was a digital pressure calibrator and its drift was taken into account in the calculation. Results show that all En values lie in acceptable limits. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by EURAMET, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

The Learning Gains and Student Perceptions of a Second Life Virtual Lab

ERIC Educational Resources Information Center

Cobb, Stephanie; Heaney, Rose; Corcoran, Olivia; Henderson-Begg, Stephanie

2009-01-01

This study examines students' reactions to the virtual biosciences laboratory developed in Second Life[R] (SL) at the University of East London. Final year undergraduates and masters students studying biotechnology took part in a trial of a virtual Polymerase Chain Reaction (PCR) experiment in Second Life and evaluated their experience by…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hu, T.A.

This is the final sample analysis report for tank 241-BX-104 (BX-104), cores 126 and 127. Two segments from each core yielded a total of 11 samples which were analyzed. The data quality objectives (DQOs) applicable to this sampling event were the Safety Screening DQO (Dukelow et al. 1995) and the Organic Safety DQO (Turner et al. 1995). The samples were received, extruded and analyzed at PNNL 325 Analytical Chemistry Laboratory (ACL). The analyses were performed in accordance with the Sample Analysis Plan (Gretsinger 1996) and indicated that the tank is safe with respect to the criteria in the Safety Screeningmore » and Organic DQO. Detailed analytical results were described in the analytical laboratory 45-day Report (Attachment 1, WHC-SD-WM-DP-171, REV. 0) and final report (Attachment 2, PNL-BX-104 REV.1) prepared by PNNL, 325 Laboratory. Corrections and/or exceptions to the PNNL final report are provided.« less

A Chance to Get Ahead: Proficiency Examinations for Clerical Laboratory Personnel. Final Report.

ERIC Educational Resources Information Center

Linehan, Jean D.

Four Proficiency Examinations for Clinical Laboratory Personnel were developed in Clinical Chemistry, Microbiology, Hematology, and Blood Banking. Purpose of project was to enable competent military laboratory technicians who lack credentials to demonstrate their job-related skills and knowledge for civilian positions, and also to help civilians…

10 CFR 707.12 - Specimen collection, handling and laboratory analysis for drug testing.

Code of Federal Regulations, 2011 CFR

2011-01-01

... drug testing. 707.12 Section 707.12 Energy DEPARTMENT OF ENERGY WORKPLACE SUBSTANCE ABUSE PROGRAMS AT DOE SITES Procedures § 707.12 Specimen collection, handling and laboratory analysis for drug testing... collection to final disposition of specimens, and testing laboratories shall use appropriate cutoff levels in...

10 CFR 707.12 - Specimen collection, handling and laboratory analysis for drug testing.

Code of Federal Regulations, 2010 CFR

2010-01-01

... drug testing. 707.12 Section 707.12 Energy DEPARTMENT OF ENERGY WORKPLACE SUBSTANCE ABUSE PROGRAMS AT DOE SITES Procedures § 707.12 Specimen collection, handling and laboratory analysis for drug testing... collection to final disposition of specimens, and testing laboratories shall use appropriate cutoff levels in...

10 CFR 707.12 - Specimen collection, handling and laboratory analysis for drug testing.

Code of Federal Regulations, 2014 CFR

2014-01-01

... drug testing. 707.12 Section 707.12 Energy DEPARTMENT OF ENERGY WORKPLACE SUBSTANCE ABUSE PROGRAMS AT DOE SITES Procedures § 707.12 Specimen collection, handling and laboratory analysis for drug testing... collection to final disposition of specimens, and testing laboratories shall use appropriate cutoff levels in...

10 CFR 707.12 - Specimen collection, handling and laboratory analysis for drug testing.

Code of Federal Regulations, 2012 CFR

2012-01-01

... drug testing. 707.12 Section 707.12 Energy DEPARTMENT OF ENERGY WORKPLACE SUBSTANCE ABUSE PROGRAMS AT DOE SITES Procedures § 707.12 Specimen collection, handling and laboratory analysis for drug testing... collection to final disposition of specimens, and testing laboratories shall use appropriate cutoff levels in...

10 CFR 707.12 - Specimen collection, handling and laboratory analysis for drug testing.

Code of Federal Regulations, 2013 CFR

2013-01-01

... drug testing. 707.12 Section 707.12 Energy DEPARTMENT OF ENERGY WORKPLACE SUBSTANCE ABUSE PROGRAMS AT DOE SITES Procedures § 707.12 Specimen collection, handling and laboratory analysis for drug testing... collection to final disposition of specimens, and testing laboratories shall use appropriate cutoff levels in...

Estimation on the self recovery behavior of low-conductivity layer in landfill final cover by laboratory conductivity tests.

PubMed

Kwon, O; Park, J

2006-11-01

This study examined the application of a Self Recovering Sustainable Layer (SRSL) as a landfill final cover. Low-conductivity layers in landfill covers are known to have problems associated with cracking as a result of the differential settlement or climatic changes. A SRSL is defined as a layer with chemical properties that reduces the increased hydraulic conductivity resulting from cracking by forming low-conductivity precipitates of chemicals contained in the layer. In this study, the formation of precipitates was confirmed using a batch test, spectroscopic analysis and mineralogical speciation tests. The possibility of secondary contamination due to the chemicals used for recovery was evaluated using a leaching test. A laboratory conductivity test was performed on a single layer composed of each chemical as well as on a 2-layer system. The recovery performance of the SRSL was estimated by developing artificial cracks in the specimens and observing the change in hydraulic conductivity as a function of time. In the laboratory conductivity test, the hydraulic conductivity of a 2-layer system as well as those of the individual layers that comprise the 2-layer system was estimated. In addition sodium ash was found to enhance the reduction in conductivity. A significant increase in conductivity was observed after the cracks developed but this was reduced with time, which indicated that the SRSL has a proper recovering performance. In conclusion, a SRSL can be used as a landfill final cover that could maintain low-conductivity even after the serious damages due to settlement.

Mars Science Laboratory Rover Closeout

NASA Image and Video Library

2011-11-10

The Mars Science Laboratory mission rover, Curiosity, is prepared for final integration into the complete NASA spacecraft in this photograph taken inside the Payload Hazardous Servicing Facility at NASA Kennedy Space Center, Fla.

Elaboration and validation of the method for the quantification of the emetic toxin of Bacillus cereus as described in EN-ISO 18465 - Microbiology of the food chain - Quantitative determination of emetic toxin (cereulide) using LC-MS/MS.

PubMed

In 't Veld, P H; van der Laak, L F J; van Zon, M; Biesta-Peters, E G

2018-04-12

A method for the quantification of the Bacillus cereus emetic toxin (cereulide) was developed and validated. The method principle is based on LC-MS as this is the most sensitive and specific method for cereulide. Therefore the study design is different from the microbiological methods validated under this mandate. As the method had to be developed a two stage validation study approach was used. The first stage (pre-study) focussed on the method applicability and the experience of the laboratories with the method. Based on the outcome of the pre-study and comments received during voting at CEN and ISO level a final method was agreed to be used for the second stage the (final) validation of the method. In the final (validation) study samples of cooked rice (both artificially contaminated with cereulide or contaminated with B. cereus for production of cereulide in the rice) and 6 other food matrices (fried rice dish, cream pastry with chocolate, hotdog sausage, mini pancakes, vanilla custard and infant formula) were used. All these samples were spiked by the participating laboratories using standard solutions of cereulide supplied by the organising laboratory. The results of the study indicate that the method is fit for purpose. Repeatability values were obtained of 0.6 μg/kg at low level spike (ca. 5 μg/kg) and 7 to 9.6 μg/kg at high level spike (ca. 75 μg/kg). Reproducibility at low spike level ranged from 0.6 to 0.9 μg/kg and from 8.7 to 14.5 μg/kg at high spike level. Recovery from the spiked samples ranged between 96.5% for mini-pancakes to 99.3% for fries rice dish. Copyright © 2018. Published by Elsevier B.V.

SUPERFUND TREATABILITY CLEARINGHOUSE: FINAL REPORT, PHASE I - IMMEDIATE ASSESSMENT, ACME SOLVENTS SITE

EPA Science Inventory

This is a site assessment and feasibility study of incineration alternatives at the ACME Solvents Site at Rockford, Illinois. The document contains laboratory results that are reported to simulate incineration conditions but no details on test methods were provided. The d...

Characterization of time-dependent changes in strength and stiffness of Florida base materials : final report, October 2008.

DOT National Transportation Integrated Search

2008-10-01

Resilient modulus and Youngs modulus are parameters increasingly used to fundamentally characterize the behavior : of pavement materials both in the laboratory and in the field. This study documents the small-strain Youngs modulus : and larger-...

Effects of combined lime and fly ash stabilization on the elastic moduli of montmorillonitic soils : final report.

DOT National Transportation Integrated Search

1988-04-01

A laboratory study using bentonite to simulate the montmorillonite component of soils common to Louisiana was undertaken to evaluate the effects of combined lime and fly ash additions on stabilization reactions. Samples containing bentonite (75 weigh...

Evaluation of Portland Cement concretes containing ground granulated blast furnace slag : final report.

DOT National Transportation Integrated Search

2002-05-01

A two part laboratory experimental program was conducted to evaluate strength and durability of various concrete mix : designs. In Part I of the study, the influence of using Grade 120 ground granulated blast furnace slag (GGBFS) on the : strength an...

Radon Mitigation Approach in a Laboratory Measurement Room

PubMed Central

Blanco-Rodríguez, Patricia; Fernández-Serantes, Luis Alfonso; Otero-Pazos, Alberto; Calvo-Rolle, José Luis; de Cos Juez, Francisco Javier

2017-01-01

Radon gas is the second leading cause of lung cancer, causing thousands of deaths annually. It can be a problem for people or animals in houses, workplaces, schools or any building. Therefore, its mitigation has become essential to avoid health problems and to prevent radon from interfering in radioactive measurements. This study describes the implementation of radon mitigation systems at a radioactivity laboratory in order to reduce interferences in the different works carried out. A large set of radon concentration samples is obtained from measurements at the laboratory. While several mitigation methods were taken into account, the final applied solution is explained in detail, obtaining thus very good results by reducing the radon concentration by 76%. PMID:28492468

Radon Mitigation Approach in a Laboratory Measurement Room.

PubMed

Blanco-Rodríguez, Patricia; Fernández-Serantes, Luis Alfonso; Otero-Pazos, Alberto; Calvo-Rolle, José Luis; de Cos Juez, Francisco Javier

2017-05-11

Radon gas is the second leading cause of lung cancer, causing thousands of deaths annually. It can be a problem for people or animals in houses, workplaces, schools or any building. Therefore, its mitigation has become essential to avoid health problems and to prevent radon from interfering in radioactive measurements. This study describes the implementation of radon mitigation systems at a radioactivity laboratory in order to reduce interferences in the different works carried out. A large set of radon concentration samples is obtained from measurements at the laboratory. While several mitigation methods were taken into account, the final applied solution is explained in detail, obtaining thus very good results by reducing the radon concentration by 76%.

Analysis of impact melt and vapor production in CTH for planetary applications

DOE PAGES

Quintana, S. N.; Crawford, D. A.; Schultz, P. H.

2015-05-19

This study explores impact melt and vapor generation for a variety of impact speeds and materials using the shock physics code CTH. The study first compares the results of two common methods of impact melt and vapor generation to demonstrate that both the peak pressure method and final temperature method are appropriate for high-speed impact models (speeds greater than 10 km/s). However, for low-speed impact models (speeds less than 10 km/s), only the final temperature method is consistent with laboratory analyses to yield melting and vaporization. Finally, a constitutive model for material strength is important for low-speed impacts because strengthmore » can cause an increase in melting and vaporization.« less

Analysis of impact melt and vapor production in CTH for planetary applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Quintana, S. N.; Crawford, D. A.; Schultz, P. H.

This study explores impact melt and vapor generation for a variety of impact speeds and materials using the shock physics code CTH. The study first compares the results of two common methods of impact melt and vapor generation to demonstrate that both the peak pressure method and final temperature method are appropriate for high-speed impact models (speeds greater than 10 km/s). However, for low-speed impact models (speeds less than 10 km/s), only the final temperature method is consistent with laboratory analyses to yield melting and vaporization. Finally, a constitutive model for material strength is important for low-speed impacts because strengthmore » can cause an increase in melting and vaporization.« less

Air Force Weapons Laboratory Computational Requirements for 1976 Through 1980

DTIC Science & Technology

1976-01-01

Air Force Weapons Laboratory , Attn: DYS, Kirtland AFB, NM 87117...final report was prepared by the Air Force Weapons Laboratory , Kirtland Air Force Base, New Mexico under Job Order 06CB. Dr. Clifford E. Rhoades, Jr... Force Base, New Mexico 87117 62601F, 06CB II. CONTROLLING OFFICE NAME AND ADDRESS Ai"- Force Weapons Laboratory / Jan 1076 Kirtland Air Force Base,

United States Air Force Summer Research Program -- 1992 High School Apprenticeship Program (HSAP) Reports. Volume 13. Phillips Laboratory

DTIC Science & Technology

1992-01-01

Research Program Phillips Laboratory I4oJ A*6Iv4 Sponsored by: Air Force Office of Scientific Research Kirtland Air ...UNITED STATES AIR FORCE SUMMER RESEARCH PROGki"A -- 1992 HIGH SCHOOL APPRENTICESHIP PROGRAM (HSAP) REPORTS VOLUME 13 (t PHILLIPS LABORATORY . RESEARCH ...Arlington High School Final Report for: Summer Research Program Geophysics Directorate Phillips Laboratory

Mars Science Laboratory Cruise Stage

NASA Image and Video Library

2011-11-10

The cruise stage of NASA Mars Science Laboratory spacecraft is being prepared for final stacking of the spacecraft in this photograph from inside the Payload Hazardous Servicing Facility at NASA Kennedy Space Center, Fla.

Final Report for Contract N00014-89-J-1967 for the Time Period from 1 May 1989 to 31 December 1990 (Texas Univ. at Austin. Applied Research Labs.)

DTIC Science & Technology

1991-04-23

in this section. In our investigation of higher order processing methods for remote acoustic sensing we sought to understand the principles of laser...magnitude less than those presently detected in laboratory measurements. An initial study of several potential higher order processing techniques was...incoherent. The use of higher order processing methods to provide some level of discrimination against noise thus appears tractable. Finally, the effects

PILOT STUDY: CCQM-P43: Tributyltin and dibutyltin in sediment

NASA Astrophysics Data System (ADS)

Wolff Briche, Céline S. J.; Wahlen, Raimund; Sturgeon, Ralph E.

2006-01-01

The pilot study CCQM P43 was undertaken to allow the assessment of the current capabilities of interested National Metrology Institutes (NIMs) (those which are members of the CCQM) and selected outside 'expert' laboratories for quantification of (C4H9)2Sn+ (DBT) and (C4H9)3Sn+ (TBT) in a prepared marine sediment. It was organised in parallel to the key comparison CCQM-K28, in which only NMIs determined TBT. This exercise was sanctioned by the 8th CCQM meeting, 18-19 April 2002, as an activity of the Inorganic Analysis Working Group and was jointly coordinated by the Institute for National Measurement Standards of the National Research Council of Canada (NRC) and LGC, UK. A total of 13 laboratories initially indicated interest (nine NMIs and four external laboratories). Only one external laboratory utilised a standard calibration approach based on natural abundance TBT and DBT standards, whereas all NMIs relied on isotope dilution mass spectrometry for quantitation (one NMI used ID-MS and an internal standard approach for the analysis of DBT). For this purpose, species specific 117Sn-enriched TBT and DBT standards were supplied by LGC. No sample preparation methodology was prescribed by the coordinating laboratories and, as a consequence, a variety of approaches was adopted by the participants, including mechanical shaking, sonication, accelerated solvent extraction, microwave assisted extraction and heating in combination with Grignard derivatization, ethylation and direct sampling. Detection techniques included ICP-MS (coupled to GC or HPLC), GC-MS and GC-AED. Main text. To reach the main text of this paper, click on Final Report. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the Mutual Recognition Arrangement (MRA).

The Induction of Chaos in Electronic Circuits Final Report-October 1, 2001

DOE Office of Scientific and Technical Information (OSTI.GOV)

R.M.Wheat, Jr.

2003-04-01

This project, now known by the name ''Chaos in Electronic Circuits,'' was originally tasked as a two-year project to examine various ''fault'' or ''non-normal'' operational states of common electronic circuits with some focus on determining the feasibility of exploiting these states. Efforts over the two-year duration of this project have been dominated by the study of the chaotic behavior of electronic circuits. These efforts have included setting up laboratory space and hardware for conducting laboratory tests and experiments, acquiring and developing computer simulation and analysis capabilities, conducting literature surveys, developing test circuitry and computer models to exercise and test ourmore » capabilities, and experimenting with and studying the use of RF injection as a means of inducing chaotic behavior in electronics. An extensive array of nonlinear time series analysis tools have been developed and integrated into a package named ''After Acquisition'' (AA), including capabilities such as Delayed Coordinate Embedding Mapping (DCEM), Time Resolved (3-D) Fourier Transform, and several other phase space re-creation methods. Many computer models have been developed for Spice and for the ATP (Alternative Transients Program), modeling the several working circuits that have been developed for use in the laboratory. And finally, methods of induction of chaos in electronic circuits have been explored.« less

Laboratory automation: total and subtotal.

PubMed

Hawker, Charles D

2007-12-01

Worldwide, perhaps 2000 or more clinical laboratories have implemented some form of laboratory automation, either a modular automation system, such as for front-end processing, or a total laboratory automation system. This article provides descriptions and examples of these various types of automation. It also presents an outline of how a clinical laboratory that is contemplating automation should approach its decision and the steps it should follow to ensure a successful implementation. Finally, the role of standards in automation is reviewed.

Retention of Esperanto Is Affected by Delay-Interval Task and Item Closure: A Partial Resolution of the Delay-Retention Effect

ERIC Educational Resources Information Center

Brosvic, Gary M.; Epstein, Michael L.; Dihoff, Roberta E.; Cook, Michael L.

2006-01-01

The present studies were undertaken to examine the effects of manipulating delay-interval task (Study 1) and timing of feedback (Study 2) on acquisition and retention. Participants completed a 100-item cumulative final examination, which included 50 items from each laboratory examination, plus 50 entirely new items. Acquisition and retention were…

Exploring the Potential of Smartphones and Tablets for Performance Support in Food Chemistry Laboratory Classes

NASA Astrophysics Data System (ADS)

van der Kolk, Koos; Hartog, Rob; Beldman, Gerrit; Gruppen, Harry

2013-12-01

Increasingly, mobile applications appear on the market that can support students in chemistry laboratory classes. In a multiple app-supported laboratory, each of these applications covers one use-case. In practice, this leads to situations in which information is scattered over different screens and written materials. Such a multiple app-supported laboratory will become awkward with the growth of the number of applications and use cases. In particular, using and switching between applications is likely to induce extraneous cognitive load that can easily be avoided. The manuscript describes the design of a prototype smartphone web app (LabBuddy) designed to support students in food chemistry laboratory classes. The manuscript describes a case study ( n = 26) of the use of a LabBuddy prototype in such a laboratory class. Based on the evaluation of this case study, design requirements for LabBuddy were articulated. LabBuddy should work on HTML5 capable devices, independent of screen size, by having a responsive layout. In addition, LabBuddy should enable a student using LabBuddy to switch between devices without much effort. Finally, LabBuddy should offer an integrated representation of information.

An Interdisciplinary Laboratory to Teach Experimentation. Final Report.

ERIC Educational Resources Information Center

Schenck, Hilbert, Jr.

The author views the primary purpose of the modern engineering laboratory as teaching the student how to experiment. An attempt is made to update the engineering laboratory and make it generally meaningful for all students, whether headed for graduate school or an industrial job. The intent is to broaden the experimental picture so that students…

Safety Tips: Academic Laboratory Waste Disposal: Yes, You Can Get Rid of that Stuff Legally!

ERIC Educational Resources Information Center

Young, Jay A.

1983-01-01

Discusses three methods for removing wastes from educational laboratories. These include paying someone with Environmental Protection Agency (EPA) permits, doing part of the work before an EPA contractor carries out final steps, or reducing magnitude of future disposal problems by changing present laboratory procedures. Includes comments on…

[Postgraduate training program in laboratory medicine at a clinical teaching hospital].

PubMed

Matsuo, Shuji

2003-04-01

The Tenri Hospital resident system was introduced in 1976 and the training program for laboratory medicine began in 1982. Thus, the author proposes goals for the the future on the basis of experience. It is appropriate that trainees study emergency tests, blood transfusion and microbiology(particularly Gram's stain and sputum culture) as practical matters, and in addition to these, learn how to reply to consultations from physicians, learn the laboratory flow(so-called laboratory system), and announce interpretations of laboratory data at reversed clinical pathological conference(R-CPC). The objectives of these training programs are to gain skills for appropriate laboratory utilization and interpretation, and develop communications and consultations with clinical pathologists and medical technologists. The key points of success in the training are close cooperation of the laboratory and teaching divisions. Particularly, cooperation with medical technologists is necessary, and it is essential medical practice for trainees because they will have to work with them in future. Finally it should be emphasized that there training has a limited effect because of the short duration. It is thus important to communicate and discuss clinical matters regularly in medicine.

Workplace Exposure to Titanium Dioxide Nanopowder Released from a Bag Filter System

PubMed Central

Ji, Jun Ho; Kim, Jong Bum; Lee, Gwangjae; Noh, Jung-Hun; Yook, Se-Jin; Cho, So-Hye; Bae, Gwi-Nam

2015-01-01

Many researchers who use laboratory-scale synthesis systems to manufacture nanomaterials could be easily exposed to airborne nanomaterials during the research and development stage. This study used various real-time aerosol detectors to investigate the presence of nanoaerosols in a laboratory used to manufacture titanium dioxide (TiO2). The TiO2 nanopowders were produced via flame synthesis and collected by a bag filter system for subsequent harvesting. Highly concentrated nanopowders were released from the outlet of the bag filter system into the laboratory. The fractional particle collection efficiency of the bag filter system was only 20% at particle diameter of 100 nm, which is much lower than the performance of a high-efficiency particulate air (HEPA) filter. Furthermore, the laboratory hood system was inadequate to fully exhaust the air discharged from the bag filter system. Unbalanced air flow rates between bag filter and laboratory hood systems could result in high exposure to nanopowder in laboratory settings. Finally, we simulated behavior of nanopowders released in the laboratory using computational fluid dynamics (CFD). PMID:26125024

A Survey of Final-year Undergraduate Laboratory Projects in Biochemistry and Related Degrees in Great Britain.

ERIC Educational Resources Information Center

Austin, Caroline A.

1997-01-01

Analyzes undergraduate research projects in biochemistry and related subjects at British universities. Discusses the trend toward students doing less research as part of their undergraduate study. Reasons cited for this trend include increased student numbers and costs. (DDR)

Laboratory evaluation of fly ash treated embankment and base materials : final report.

DOT National Transportation Integrated Search

1988-04-01

This study was undertaken to provide the Louisiana DOTD with a data base from which recommendations can be made concerning the modification or stabilization of soils using a Class C fly ash as a full or partial replacement for hydraulic cement or hyd...

Modulus of elasticity, creep and shrinkage of concrete, phase II : part 1, creep study, final report.

DOT National Transportation Integrated Search

2009-10-01

A laboratory testing program was performed to evaluate the physical and mechanical properties of typical Class II, IV, V, and VI concrete mixtures made with a Miami Oolite limestone, a Georgia granite, and a lightweight aggregate Stalite, including c...

Spring 2005 Industry Study. Strategic Materials

DTIC Science & Technology

2005-01-01

Research Laboratory, Weapons and Materials Research Center. Presented at ARL, Aberdeen, MD. March 17, 2005. Ashley, Steven. “ Alchemy of a...Spring 2005 Industry Study Final Report Strategic Materials The Industrial College of the Armed Forces National...the collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data

KEY COMPARISON: CCEM.RF-K18.CL (GT-RF/00-1): Noise in 50 Ω coaxial line at frequencies up to 1 GHz

NASA Astrophysics Data System (ADS)

Eiø, Christopher; Adamson, David; Randa, James; Allal, Djamel; Uzdin, Rinadij

2006-01-01

A measurement comparison of noise temperature has been carried out between four national metrology laboratories in coaxial line at 30 MHz, 60 MHz and 1 GHz. The identification of this intercomparison is CCEM.RF-K18.CL. Two noise sources have been measured. The following four national laboratories participated in this intercomparison: NPL (United Kingdom), NIST (United States of America), BNM-LNE (France) and VNIIFTRI (Russia). The National Physical Laboratory (UK) acted as the pilot laboratory for the comparison. It can be seen that there is generally good agreement between the laboratories. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).

Women's experiences in the engineering laboratory in Japan

NASA Astrophysics Data System (ADS)

Hosaka, Masako

2014-07-01

This qualitative study aims to examine Japanese women undergraduate engineering students' experiences of interacting with departmental peers of the same year in the laboratory setting by using interview data of 32 final-year students at two modestly selective national universities in Japan. Expectation state theory that explains unequal relationship between men and women is used as a framework. Findings suggest that women generally had a discouraging experience while working with their male peers. Specifically, women participated less and lost confidence by comparing with the men who appeared to be confident and competent.

Infrared thermography applied to the study of heated and solar pavement: from numerical modeling to small scale laboratory experiments

NASA Astrophysics Data System (ADS)

Le Touz, N.; Toullier, T.; Dumoulin, J.

2017-05-01

The present study addresses the thermal behaviour of a modified pavement structure to prevent icing at its surface in adverse winter time conditions or overheating in hot summer conditions. First a multi-physic model based on infinite elements method was built to predict the evolution of the surface temperature. In a second time, laboratory experiments on small specimen were carried out and the surface temperature was monitored by infrared thermography. Results obtained are analyzed and performances of the numerical model for real scale outdoor application are discussed. Finally conclusion and perspectives are proposed.

[Views of final-year medical students at Damascus University about clinical skills acquired before graduation].

PubMed

Alourfi, Z; Hassan, R El Sayed; Koudsi, A

2012-06-01

Medical education in Syrian universities is facing many challenges that may affect the quality of the education and the standard of graduates. We therefore conducted a cross-sectional study using a self-administrated questionnaire with 76 items to investigate the perceptions of 290 final-year medical students regarding the confidence of performing some core clinical skills. A total of 271 responded (response rate 93.4%). Student responses differed. While confidence was highest for skills that do not require practice in the clinical skills laboratory, it was low for skills that need training in emergency and intensive care units, or when students were participating in patient care with partial responsibility. Our findings confirm the need for effective clinical laboratory training, student participation in emergency room shifts, and that students to be allowed to take some egree of responsibility.

Laboratory testing in primary care: A systematic review of health IT impacts.

PubMed

Maillet, Éric; Paré, Guy; Currie, Leanne M; Raymond, Louis; Ortiz de Guinea, Ana; Trudel, Marie-Claude; Marsan, Josianne

2018-08-01

Laboratory testing in primary care is a fundamental process that supports patient management and care. Any breakdown in the process may alter clinical information gathering and decision-making activities and can lead to medical errors and potential adverse outcomes for patients. Various information technologies are being used in primary care with the goal to support the process, maximize patient benefits and reduce medical errors. However, the overall impact of health information technologies on laboratory testing processes has not been evaluated. To synthesize the positive and negative impacts resulting from the use of health information technology in each phase of the laboratory 'total testing process' in primary care. We conducted a systematic review. Databases including Medline, PubMed, CINAHL, Web of Science and Google Scholar were searched. Studies eligible for inclusion reported empirical data on: 1) the use of a specific IT system, 2) the impacts of the systems to support the laboratory testing process, and were conducted in 3) primary care settings (including ambulatory care and primary care offices). Our final sample consisted of 22 empirical studies which were mapped to a framework that outlines the phases of the laboratory total testing process, focusing on phases where medical errors may occur. Health information technology systems support several phases of the laboratory testing process, from ordering the test to following-up with patients. This is a growing field of research with most studies focusing on the use of information technology during the final phases of the laboratory total testing process. The findings were largely positive. Positive impacts included easier access to test results by primary care providers, reduced turnaround times, and increased prescribed tests based on best practice guidelines. Negative impacts were reported in several studies: paper-based processes employed in parallel to the electronic process increased the potential for medical errors due to clinicians' cognitive overload; systems deemed not reliable or user-friendly hampered clinicians' performance; and organizational issues arose when results tracking relied on the prescribers' memory. The potential of health information technology lies not only in the exchange of health information, but also in knowledge sharing among clinicians. This review has underscored the important role played by cognitive factors, which are critical in the clinician's decision-making, the selection of the most appropriate tests, correct interpretation of the results and efficient interventions. By providing the right information, at the right time to the right clinician, many IT solutions adequately support the laboratory testing process and help primary care clinicians make better decisions. However, several technological and organizational barriers require more attention to fully support the highly fragmented and error-prone process of laboratory testing. Copyright © 2018 Elsevier B.V. All rights reserved.

Nuclear Air Blast Effects.

DTIC Science & Technology

1982-06-01

AD-All? 43 SCIENCE APPLICATZOhu INC NCLAA VA F/6 19/4I NUICLEAR AIR BLAST IFPCTS(U) JUR " PRY UNCLASSIFID SAI-63-636-VA NLOOI I-C lit? I. 1174~ 132...SiCuftIt, CLASSFICA?1lOw OF fl.IS PAQ-C( fhbl Dal. Lnt.,.d, REPORT DOCUMENTATION4 PAGE apoI ct~ NUCLEAR AIR BLAST EFFECTS FINAL REPORT SAI-83-836-WA...TUCSON a WASHINGTON NUCLEAR AIR BLAST EFFECTS FINAL REPORT SAI-83-836-WA Submitted to: Laboratory for Computational Physics Naval Research Laboratory

OPALS Final Testing

NASA Image and Video Library

2014-07-24

Optical PAyload for Lasercomm Science OPALS flight terminal undergoes final testing at NASA Jet Propulsion Laboratory. OPALS was launched to the International Space Station from Cape Canaveral Air Force Station in Florida on April 18, 2014.

Lime utilization in the laboratory, field, and design of pavement layers : final report.

DOT National Transportation Integrated Search

2017-01-01

The objective of this study was to review and report the best practices of using lime (i.e., granulated lime, hydrated lime, and slurry lime) to dry soil, in working tables, and in pavement applications. The project also reviewed and documented the i...

Effects of aggregate gradation, aggregate type, and SBS polymer-modified binder on Florida HMAC fracture energy properties : final report, March 2009.

DOT National Transportation Integrated Search

2009-03-01

"The primary objective of this research study was to evaluate the fracture mechanics properties of HMA concrete for Superpave mixtures. An experimental program was performed on asphalt mixtures with various types of materials. The laboratory testing ...

USAF Summer Research Program - 1993 Summer Research Extension Program Final Reports, Volume 2, Phillips Laboratory

DTIC Science & Technology

1994-11-01

Research Extension Program Phillips Laboratory Kirtland Air Force Base Sponsored by: Air Force Office of Scientific Research Boiling Air Force Base...Program Phillips Laboratory Sponsored by: Air Force Office of Scientific Research Bolling Air Force Base, Washington, D.C. and Arkansas Tech University...Summer Research Extension Program (SREP) Phillips

Evaluation of hydrothermal resources of North Dakota. Phase II. Final technical report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harris, K.L.; Howell, F.L.; Winczewski, L.M.

1981-06-01

This evaluation of the hydrothermal resources of North Dakota is based on existing data on file with the North Dakota Geological Survey (NDGS) and other state and federal agencies, and field and laboratory studies conducted. The principal sources of data used during the Phase II study were WELLFILE, the computer library of oil and gas well data developed during the Phase I study, and WATERCAT, a computer library system of water well data assembled during the Phase II study. A field survey of the shallow geothermal gradients present in selected groundwater observation holes was conducted. Laboratory determinations of the thermalmore » conductivity of core samples is being done to facilitate heat-flow calculations on those hole-of-convenience cased.« less

Evaluation of hydrothermal resources of North Dakota. Phase III final technical report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harris, K.L.; Howell, F.L.; Wartman, B.L.

1982-08-01

The hydrothermal resources of North Dakota were evaluated. This evaluation was based on existing data on file with the North Dakota Geological Survey (NDGS) and other state and federal agencies, and field and laboratory studies conducted. The principal sources of data used during the study were WELLFILE, the computer library of oil and gas well data developed during the Phase I study, and WATERCAT, a computer library system of water well data assembled during the Phase II study. A field survey of the shallow geothermal gradients present in selected groundwater observation holes was conducted. Laboratory determinations of the thermal conductivitymore » of core samples were done to facilitate heat-flow calculations on those holes-of-convenience cased.« less

78 FR 110 - Supplemental Record of Decision; Final Supplementary Risk Assessment for the Boston University...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-02

... partially fund the construction of a state-of-the-art National Biocontainment Laboratory (NBL), the National... state-of-the-art National Biocontainment Laboratory (NBL), the National Emerging Infectious Diseases...

Mars Science Laboratory Spacecraft During Cruise, Artist Concept

NASA Image and Video Library

2011-10-03

This is an artist concept of NASA Mars Science Laboratory spacecraft during its cruise phase between launch and final approach to Mars. The spacecraft includes a disc-shaped cruise stage on the left attached to the aeroshell.

An Experimental Study of the Project CRISS Reading Program on Grade 9 Reading Achievement in Rural High Schools. Final Report NCEE 2011-4007

ERIC Educational Resources Information Center

Kushman, Jim; Hanita, Makoto; Raphael, Jacqueline

2011-01-01

Students entering high school face many new academic challenges. One of the most important is their ability to read and understand more complex text in literature, mathematics, science, and social studies courses as they navigate through a rigorous high school curriculum. The Regional Educational Laboratory (REL) Northwest conducted a study to…

Scientific Support for NQR Explosive Detection Development

DTIC Science & Technology

2006-07-01

Final 3. DATES COVERED (From - To) 8 March 2004 - 7 March 2006 4. TITLE AND SUBTITLE Scientific Support for NQR Explosive Detection Development...Laboratory (NRL) to improve explosive detection using nuclear quadrupole resonance ( NQR ) is summarized. The work includes studies of the effects...superconducting coils for explosive detection. Additional studies involving slowly rotating NQR measurements were also pursued. 15. SUBJECT TERMS Nuclear

Student Ownership of Projects in an Upper-Division Optics Laboratory Course: A Multiple Case Study of Successful Experiences

ERIC Educational Resources Information Center

Dounas-Frazer, Dimitri R.; Stanley, Jacob T.; Lewandowski, H. J.

2017-01-01

We investigate students' sense of ownership of multiweek final projects in an upper-division optics lab course. Using a multiple case study approach, we describe three student projects in detail. Within-case analyses focused on identifying key issues in each project, and constructing chronological descriptions of those events. Cross-case analysis…

The American Government Information Unit: A Pilot Program to Improve Information Flow Between Research and Development and Practice in Education. Final Report.

ERIC Educational Resources Information Center

Adelson, Nancy C.; And Others

The Laboratory staff reported the unit development and field test activities in their effort to collect, analyze, synthesize, and disseminate new curriculum developments in secondary level social studies to school curriculum decision makers. The audience consisted primarily of social studies teachers and department chairmen. To further refine and…

Corrections of clinical chemistry test results in a laboratory information system.

PubMed

Wang, Sihe; Ho, Virginia

2004-08-01

The recently released reports by the Institute of Medicine, To Err Is Human and Patient Safety, have received national attention because of their focus on the problem of medical errors. Although a small number of studies have reported on errors in general clinical laboratories, there are, to our knowledge, no reported studies that focus on errors in pediatric clinical laboratory testing. To characterize the errors that have caused corrections to have to be made in pediatric clinical chemistry results in the laboratory information system, Misys. To provide initial data on the errors detected in pediatric clinical chemistry laboratories in order to improve patient safety in pediatric health care. All clinical chemistry staff members were informed of the study and were requested to report in writing when a correction was made in the laboratory information system, Misys. Errors were detected either by the clinicians (the results did not fit the patients' clinical conditions) or by the laboratory technologists (the results were double-checked, and the worksheets were carefully examined twice a day). No incident that was discovered before or during the final validation was included. On each Monday of the study, we generated a report from Misys that listed all of the corrections made during the previous week. We then categorized the corrections according to the types and stages of the incidents that led to the corrections. A total of 187 incidents were detected during the 10-month study, representing a 0.26% error detection rate per requisition. The distribution of the detected incidents included 31 (17%) preanalytic incidents, 46 (25%) analytic incidents, and 110 (59%) postanalytic incidents. The errors related to noninterfaced tests accounted for 50% of the total incidents and for 37% of the affected tests and orderable panels, while the noninterfaced tests and panels accounted for 17% of the total test volume in our laboratory. This pilot study provided the rate and categories of errors detected in a pediatric clinical chemistry laboratory based on the corrections of results in the laboratory information system. A direct interface of the instruments to the laboratory information system showed that it had favorable effects on reducing laboratory errors.

Mars Science Laboratory Heat Shield Integration for Flight

NASA Image and Video Library

2011-11-10

During final stacking of NASA Mars Science Laboratory spacecraft, the heat shield is positioned for integration with the rest of the spacecraft in this photograph from inside the Payload Hazardous Servicing Facility at NASA Kennedy Space Center, Fla.

Four Finalist Landing Site Candidates for Mars Science Laboratory

NASA Image and Video Library

2008-11-19

Out of more than 30 sites considered as possible landing targets for NASA Mars Science Laboratory mission, by November 2008 four of the most intriguing places on Mars rose to the final round of the site-selection process.

Implementation of Scientific Community Laboratories and Their Effect on Student Conceptual Learning, Attitudes, and Understanding of Uncertainty

NASA Astrophysics Data System (ADS)

Lark, Adam

Scientific Community Laboratories, developed by The University of Maryland, have shown initial promise as laboratories meant to emulate the practice of doing physics. These laboratories have been re-created by incorporating their design elements with the University of Toledo course structure and resources. The laboratories have been titled the Scientific Learning Community (SLC) Laboratories. A comparative study between these SLC laboratories and the University of Toledo physics department's traditional laboratories was executed during the fall 2012 semester on first semester calculus-based physics students. Three tests were executed as pre-test and post-tests to capture the change in students' concept knowledge, attitudes, and understanding of uncertainty. The Force Concept Inventory (FCI) was used to evaluate students' conceptual changes through the semester and average normalized gains were compared between both traditional and SLC laboratories. The Colorado Learning Attitudes about Science Survey for Experimental Physics (E-CLASS) was conducted to elucidate students' change in attitudes through the course of each laboratory. Finally, interviews regarding data analysis and uncertainty were transcribed and coded to track changes in the way students understand uncertainty and data analysis in experimental physics after their participation in both laboratory type. Students in the SLC laboratories showed a notable an increase conceptual knowledge and attitudes when compared to traditional laboratories. SLC students' understanding of uncertainty showed most improvement, diverging completely from students in the traditional laboratories, who declined throughout the semester.

Overview of Heavy Ion Fusion Accelerator Research in the U. S.

NASA Astrophysics Data System (ADS)

Friedman, Alex

2002-12-01

This article provides an overview of current U.S. research on accelerators for Heavy Ion Fusion, that is, inertial fusion driven by intense beams of heavy ions with the goal of energy production. The concept, beam requirements, approach, and major issues are introduced. An overview of a number of new experiments is presented. These include: the High Current Experiment now underway at Lawrence Berkeley National Laboratory; studies of advanced injectors (and in particular an approach based on the merging of multiple beamlets), being investigated experimentally at Lawrence Livermore National Laboratory); the Neutralized (chamber) Transport Experiment being assembled at Lawrence Berkeley National Laboratory; and smaller experiments at the University of Maryland and at Princeton Plasma Physics Laboratory. The comprehensive program of beam simulations and theory is outlined. Finally, prospects and plans for further development of this promising approach to fusion energy are discussed.

A Semester-Long Project-Oriented Biochemistry Laboratory Based on Helicobacter pylori Urease

PubMed Central

Farnham, Kate R.; Dube, Danielle H.

2015-01-01

Here we present the development of a thirteen-week project-oriented biochemistry laboratory designed to introduce students to foundational biochemical techniques and then enable students to perform original research projects once they have mastered these techniques. In particular, we describe a semester-long laboratory that focuses on a biomedically relevant enzyme – Helicobacter pylori (Hp) urease – the activity of which is absolutely required for the gastric pathogen Hp to colonize the human stomach. Over the course of the semester, students undertake a biochemical purification of Hp urease, assess the success of their purification, and investigate the activity of their purified enzyme. In the final weeks of the semester, students design and implement their own experiments to study Hp urease. This laboratory provides students with an understanding of the importance of biochemistry in human health while empowering them to engage in an active area of research. PMID:26173574

A semester-long project-oriented biochemistry laboratory based on Helicobacter pylori urease.

PubMed

Farnham, Kate R; Dube, Danielle H

2015-01-01

Here we present the development of a 13 week project-oriented biochemistry laboratory designed to introduce students to foundational biochemical techniques and then enable students to perform original research projects once they have mastered these techniques. In particular, we describe a semester-long laboratory that focuses on a biomedically relevant enzyme--Helicobacter pylori (Hp) urease--the activity of which is absolutely required for the gastric pathogen Hp to colonize the human stomach. Over the course of the semester, students undertake a biochemical purification of Hp urease, assess the success of their purification, and investigate the activity of their purified enzyme. In the final weeks of the semester, students design and implement their own experiments to study Hp urease. This laboratory provides students with an understanding of the importance of biochemistry in human health while empowering them to engage in an active area of research. © 2015 The International Union of Biochemistry and Molecular Biology.

Stirling Laboratory Research Engine: Preprototype configuration report

NASA Technical Reports Server (NTRS)

Hoehn, F. W.

1982-01-01

The concept of a simple Stirling research engine that could be used by industrial, university, and government laboratories was studied. The conceptual and final designs, hardware fabrication and the experimental validation of a preprototype stirling laboratory research engine (SLRE) were completed. Also completed was a task to identify the potential markets for research engines of this type. An analytical effort was conducted to provide a stirling cycle computer model. The versatile engine is a horizontally opposed, two piston, single acting stirling engine with a split crankshaft drive mechanism; special instrumentation is installed at all component interfaces. Results of a thermodynamic energy balance for the system are reported. Also included are the engine performance results obtained over a range of speeds, working pressures, phase angles and gas temperatures. The potential for a stirling research engine to support the laboratory requirements of educators and researchers was demonstrated.

Remote Sensing of Landuse Changes and Implications for Landuse Policy

NASA Technical Reports Server (NTRS)

Kennedy, Ken

1996-01-01

This final report describes grant activities under which students were to study landuse changes by comparing planning and zoning documents using remote sensed data data analyzed and interpreted in the laboratory. Students were recruited through mathematics, political science and engineering classes an clubs. Work protocols were then organized for research on the county's growth patterns over the last three decades. Students and investigators made planes to identify specific scenes in Landsat and other data which would satisfy the research parameters. Finally, statistical and imaging software was identified and some was acquired.

Demonstration of a Model-Based Technology for Monitoring Water Quality and Corrosion in Water-Distribution systems

DTIC Science & Technology

2016-12-01

Kamojjala, 2014, “Real-Time M0deling of Water Distribution Systems: A Case Study ,” Journal AWWA, Vol. 106, No. 9 (September 2014.) Feinauer, Lynn R...Quality and Corrosion in Water-Distribution Systems Final Report on Project F07-AR05 Co ns tr uc tio n En gi ne er in g R es ea rc h La bo ra to...Final Report on Project F07-AR05 Vicki L. Van Blaricum Construction Engineering Research Laboratory U.S. Army Engineer Research and Development Center

Student Reciprocal Peer Teaching as a Method for Active Learning: An Experience in an Electrotechnical Laboratory

NASA Astrophysics Data System (ADS)

Muñoz-García, Miguel A.; Moreda, Guillermo P.; Hernández-Sánchez, Natalia; Valiño, Vanesa

2013-10-01

Active learning is one of the most efficient mechanisms for learning, according to the psychology of learning. When students act as teachers for other students, the communication is more fluent and knowledge is transferred easier than in a traditional classroom. This teaching method is referred to in the literature as reciprocal peer teaching. In this study, the method is applied to laboratory sessions of a higher education institution course, and the students who act as teachers are referred to as "laboratory monitors." A particular way to select the monitors and its impact in the final marks is proposed. A total of 181 students participated in the experiment, experiences with laboratory monitors are discussed, and methods for motivating and training laboratory monitors and regular students are proposed. The types of laboratory sessions that can be led by classmates are discussed. This work is related to the changes in teaching methods in the Spanish higher education system, prompted by the Bologna Process for the construction of the European Higher Education Area

Cathode Research and the Threshold Cathode Test Facility

DTIC Science & Technology

2002-09-01

SYSTEM (LEFT) AND PULSED POWER TANK (RIGHT ) AS ASSEMBLED AT THE AIR FORCE RESEARCH LABORATORY , DIRECTED ENERGY DIRECTORATE AT KIRTLAND AFB, NM...Final Report APPROVED FOR PUBLIC RELEASE; DISTRIBUTION IS UNLIMITED. AIR FORCE RESEARCH LABORATORY Directed Energy Directorate 3550 Aberdeen Ave SE... Research Laboratory ( AFRL ), Directed Energy Directorate at Kirtland AFB, NM. In addition, simulations were performed that shed new light on the

Design of the rivaroxaban for heparin-induced thrombocytopenia study.

PubMed

Linkins, Lori-Ann; Warkentin, Theodore E; Pai, Menaka; Shivakumar, Sudeep; Manji, Rizwan A; Wells, Philip S; Crowther, Mark A

2014-11-01

Rivaroxaban is an ideal potential candidate for treatment of heparin-induced thrombocytopenia (HIT) because it is administered orally by fixed dosing, requires no laboratory monitoring and is effective in the treatment of venous and arterial thromboembolism in other settings. The Rivaroxaban for HIT study is a prospective, multicentre, single-arm, cohort study evaluating the incidence of new symptomatic venous and arterial thromboembolism in patients with suspected or confirmed HIT who are treated with rivaroxaban. Methodological challenges faced in the design of this study include heterogeneity of the patient population, differences in the baseline risk of thrombosis and bleeding dependent on whether HIT is confirmed or just suspected, and heterogeneity in laboratory confirmation of HIT. The rationale for how these challenges were addressed and the final design of the Rivaroxaban for HIT study is reviewed.

The sensitivity of aquatic insects to divalent metals: a comparative analysis of laboratory and field data.

PubMed

Brix, Kevin V; DeForest, David K; Adams, William J

2011-09-15

Laboratory studies have traditionally indicated that aquatic insects are relatively insensitive to metals while field studies have suggested them to be among the most sensitive aquatic invertebrate taxa. We reviewed and synthesized available studies in the literature to critically assess why this discrepancy exists. Despite the intense effort to study the effects of metals on aquatic biota over the past several decades, we found studies specific to insects to still be relatively limited. In general, the discrepancy between laboratory and field studies continues with few efforts having been made to elucidate the ecological and physiological mechanisms that underlie the relative sensitivity (or insensitivity) of aquatic insects to metals. However, given the limited data available, it appears that aquatic insects are indeed relatively insensitive to acute metal exposures. In contrast, we suggest that some aquatic insect taxa may be quite sensitive to chronic metal exposure and in some cases may not be protected by existing water quality criteria for metals. The discrepancy between laboratory and field studies with respect to chronic sensitivity appears to largely be driven by the relatively short exposure periods in laboratory studies as compared to field studies. It also appears that, in some cases, the sensitivity of aquatic insects in field studies may be the result of direct effects on primary producers, which lead to indirect effects via the food chain on aquatic insects. Finally, available evidence suggests that diet is an important source of metal accumulation in insects, but to date there have been no conclusive studies evaluating whether dietary metal accumulation causes toxicity. There is a clear need for developing a more mechanistic understanding of aquatic insect sensitivity to metals in long-term laboratory and field studies. Copyright © 2011 Elsevier B.V. All rights reserved.

Teaching method validation in the clinical laboratory science curriculum.

PubMed

Moon, Tara C; Legrys, Vicky A

2008-01-01

With the Clinical Laboratory Improvement Amendment's (CLIA) final rule, the ability of the Clinical Laboratory Scientist (CLS) to perform method validation has become increasingly important. Knowledge of the statistical methods and procedures used in method validation is imperative for clinical laboratory scientists. However, incorporating these concepts in a CLS curriculum can be challenging, especially at a time of limited resources. This paper provides an outline of one approach to addressing these topics in lecture courses and integrating them in the student laboratory and the clinical practicum for direct application.

Evaluation of a nuclear asphalt content gage : final report.

DOT National Transportation Integrated Search

1970-01-01

The Troxler Model 2226 asphalt content gauge was evaluated in the laboratory and taken into the field where its results were compared to conventional reflux values. The precision as evaluated in the laboratory was found to be excellent - equivalent t...

Effect of percentage baghouse fines on the amount and type of anti-stripping agent required to control moisture sensitivity : final report.

DOT National Transportation Integrated Search

2003-06-30

This study investigated the effect of moisture and amount of baghouse fines on AC mixes. Two : types of baghouse fines, each with a different gradation, were used in varying concentrations to prepare : laboratory samples. The binder used was PG64-22 ...

Distribution of end bearing, tip shear and rotation on drilled shafts with combined loading in Florida limestone : final report, May 2008.

DOT National Transportation Integrated Search

2008-05-01

The study investigated the behavior of large diameter drilled shafts embedded short distances in Florida Limestone (i.e. L/D=1 &3). The work was performed via laboratory (centrifuge) tests and at two field sites (17th Street and Fuller Warren Bridges...

The School Performance of Post-H. Influenza Meningitic Children. Final Report.

ERIC Educational Resources Information Center

Pate, John E.

Reported was a project studying the school performance of children who had survived laboratory confirmed Haemophilus influenza meningitis prior to 4 years of age without observable sequelae and who were enrolled in regular primary grades. Thirty-nine index children were matched with controls by age, sex, socioeconomic level, and classroom…

Evaluation of Employer, Teacher, and Student Perceptions of CO-OP/PEL. Final Report.

ERIC Educational Resources Information Center

Hogue, Ken; And Others

A study compared the effectiveness of on-the-job work experience (CO-OP) with pre-employment laboratory experience (PEL) of the six instructional areas in vocational education. This was accomplished by obtaining the perceptions of program completers (1983 graduates), participating employers, and vocational education teachers from seven sample…

Incidental and Context-Responsive Activation of Structure- and Function-Based Action Features during Object Identification

ERIC Educational Resources Information Center

Lee, Chia-lin; Middleton, Erica; Mirman, Daniel; Kalenine, Solene; Buxbaum, Laurel J.

2013-01-01

Previous studies suggest that action representations are activated during object processing, even when task-irrelevant. In addition, there is evidence that lexical-semantic context may affect such activation during object processing. Finally, prior work from our laboratory and others indicates that function-based ("use") and structure-based…

Evaluation of several types of curing and protective materials for concrete : final report on part I : laboratory and outdoor exposure studies preliminary to field trials.

DOT National Transportation Integrated Search

1970-01-01

Concern for improving the durability of concrete has focused renewed attention on all aspects of concrete technology. Numerous proprietary products which are claimed to improve durability have been marketed as protective coatings, curing agents or co...

Language Acquisition: Some Acoustic and Interactive Aspects of Infancy. Final Report.

ERIC Educational Resources Information Center

Zlatin, Marsha A.; Horii, Yoshiyuki

This longitudinal study examines the early stages of language acquisition in four first-born infants from birth to two years. Selected aspects of vocal-verbal behavior exhibited by the children and their parents were examined. Home and laboratory recordings, diaries, interviews, and developmental observation were principal data sources. Substudies…

Time rate of local scour at complex bridge piers field and laboratory analyses : final report, April 2009.

DOT National Transportation Integrated Search

2009-04-01

A local scour evolution field study was conducted under this contract. One of the piers on the A1A Bridge over the Intracoastal Waterway (ICCW) in Fort Pierce, Florida was selected for the test site. The existing local scour hole was filled with sand...

Thinking about Evolution: Combinatorial Play as a Strategy for Exercising Scientific Creativity

ERIC Educational Resources Information Center

Wingate, Richard J. T.

2011-01-01

An enduring focus in education on how scientists formulate experiments and "do science" in the laboratory has excluded a vital element of scientific practice: the creative and imaginative thinking that generates models and testable hypotheses. In this case study, final-year biomedical sciences university students were invited to create and justify…

Final report of the SIM.QM-S7 supplementary comparison, trace metals in drinking water

NASA Astrophysics Data System (ADS)

Yang, Lu; Nadeau, Kenny; Gedara Pihillagawa, Indu; Meija, Juris; Grinberg, Patricia; Mester, Zoltan; Valle Moya, Edith; Solís González, Faviola Alejandra; del Rocio Arvizu Torres, María; Yañez Muñoz, Oscar; Velina Lara-Manzano, Judith; Mazzitello, Gisela; Prina, Pedro; Acosta, Osvaldo; Napoli, Romina; Pérez Zambra, Ramiro; Ferreira, Elizabeth; Dobrovolskiy, Vladimir; Aprelev, Aleksei; Stakheev, Aleksei; Frolov, Dmitriy; Gusev, Leonid; Ivanova, Veronika; Näykki, Teemu; Sara-Aho, Timo; Venegas Padilla, Jimmy; Acuña Cubillo, Carlos; Bremmer, Dwyte; Freemantle, Ruel; Taebunpakul, Sutthinun; Tangpaisarnkul, Nongluck; Rodruangthum, Patumporn; Kaewkhomdee, Nattikarn; Thiengmanee, Usana; Tangjit, Tararat; Buzoianu, Mirella; Alejandro Ahumada Forigua, Diego; Abella Gamba, Johanna Paola; Alfredo Chavarro Medina, Luis; Sobina, Egor; Tabatchikova, Tatyana; Alexopoulos, Charalambos; Kakoulides, Elias; Delgado, Mabel; Flores, Liliana; Knox, Saira; Siewlal, Kester; Maharaj, Avinash

2018-01-01

SIM.QM-S7 was performed to assess the analytical capabilities of National Metrology Institutes (NMIs) and Designated Institutes (DIs) of SIM members (or other regions) for the accurate determination of trace metals in drinking water. The study was proposed by the coordinating laboratories National Research Council Canada (NRC) and Centro Nacional de Metrologia (CENAM) as an activity of Inorganic Analysis Working Group (IAWG) of Consultative Committee for Amount of Substance - Metrology in Chemistry and Biology (CCQM). Participants included 16 NMIs/DIs from 15 countries. No measurement method was prescribed by the coordinating laboratories. Therefore, NMIs used measurement methods of their choice. However, the majority of NMIs/DIs used ICP-MS. This SIM.QM-S7 Supplementary Comparison provides NMIs/DIs with the needed evidence for CMC claims for trace elements in fresh waters and similar matrices. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Effect of skill laboratory training on academic performance of medical students.

PubMed

Khan, Muhammad Alamgir; Shabbir, Faizania; Qamar, Khadija; Rajput, Tausif Ahmed

2017-05-01

To observe the effect of skill lab training on academic performance of final year medical students in terms of marks obtained in long case, short case, objective structured clinical examination and viva. The cross-sectional comparative study was conducted at Army Medical College, Rawalpindi from February to April 2015. Two batches of final year MBBS were recruited for the study. Batch 1 received conventional training, and Batch 2 received skill lab training. The performance of students was assessed by comparing the marks obtained in long case, short case, objective structured clinical examination and viva. Data was analysed using SPSS 23. Of the 335 subjects, 168(50.1%) were male and 167(49.9%) were female students with a mean age of 21.79±1.02 years. Batch 1 had 151(45%) students and Batch 2 had 184(55%). Batch 2 got significantly higher marks in long case, short case and objective structured clinical examination (p<0.05 each). Viva result was not found to be related to training (p>0.05). Acquisition of clinical skills significantly improved when medial students were trained in skill laboratories.

Review of Research on Teachers’ Pedagogical Judgments, Plans, and Decisions,

DTIC Science & Technology

1982-11-01

simulation studies; and (3) training studies. Four laboratory and classroom studies have examined the degree to which reading clinicians and classroom teachers...clinicians who diagnosed the same cases. Finally, training teachers to conduct a systematic diagnosis of a reading problem increased the accuracy of their...evidence that training can overcome these inaccuracies to some degree, additional research on teachers’ judgmental processes is needed. Such research

Final report of AFRIMETS.M.M-S6: supplementary comparison of 100 mg, 100 g 500 g, 1 kg and 5 kg stainless steel mass standards

NASA Astrophysics Data System (ADS)

Mautjana, R. T.; Molefe, P. T.; Mayindu, N. F.; Armah, M. N.; Ramasawmy, V.; Albasini, G. L.; Matali, S.; Richmond, H.; Rusimbi, V.; Kiwanuka, J.; Mutale, D. M.; Mutsimba, F.

2018-01-01

This report summarizes the results of AFRIMETS.M.M-S6 mass standards comparison conducted between eleven participating laboratories/countries. Two sets of five weights with nominal values 100 mg, 100 g, 500 g, 1 kg and 5 kg were used as the traveling standards. These nominal values were decided from the needs of participating laboratories submitted to the pilot laboratory through a questionnaire and agreed upon by all participants. The traveling standards were hand carried between laboratories starting from February 2014 and were received from the last participants in October 2014. The programme was coordinated by National Metrology Institute of South Africa (NMISA), who provided the travelling standards and reference values for the comparison. The corrections to the BIPM as-maintained mass unit [5] have insignificant influence on the results of this comparison. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Interagency Federal Laboratory Review Final Report

DTIC Science & Technology

1995-05-15

technology. DOE labs have made unique contributions to national security since the days of the Manhattan Project , in designing, developing, and...Weapons Responsibility Most of DOE’s large multi-program laboratories had their origin in the Manhattan Project , to develop nuclear weapons during and

Fieberling Guyot Studies.

DTIC Science & Technology

1991-07-01

volcanoes in the chain which have already been completely surveyed by Seabeam (e.g. Jasper Seamount ). During the bathymetric survey amplitude data from...geometry and mobility is retuired for interpretation of the boundary layer physics and ecology and distribution of tie benthic infauna. 2 ...Marine Physical Laboratory J,;AD-NA3 19 Fieberling Guyot Studies Final Report Prepared for the Office of Naval Research Department of the Navy for

United States Air Force Summer Research Program -- 1993 Summer Research Program Final Reports. Volume 10. Wright Laboratory

DTIC Science & Technology

1993-01-01

LABORATORIES 5800 Uplander Way Culver City, CA 90230-6608 Program Director, RDL Program Manager , AFOSR Gary Moore Col. Hal Rhoades Program Manager , RDL...Laboratory: PL/RK Aerospace Engineering University of Cinc nati Vol-Page No: 8-10 Cincinnati, OH 45221-0000 Burns, Paul Field: Electrical Engineering as...Laboratory: PL/GP Electrical Engineering Boston University Vol-Page No: a- 5 Boston, MA 2215-0000 GSRP Participant Data Stauffer, Joseph Field: Management MS

Michigan/Air Force Research Laboratory (AFRL) Collaborative Center in Control Science (MACCCS)

DTIC Science & Technology

2016-09-01

AFRL-RQ-WP-TR-2016-0139 MICHIGAN/AIR FORCE RESEARCH LABORATORY (AFRL) COLLABORATIVE CENTER IN CONTROL SCIENCE (MACCCS) Anouck Girard...Final 18 April 2007 – 30 September 2016 4. TITLE AND SUBTITLE MICHIGAN/AIR FORCE RESEARCH LABORATORY (AFRL) COLLABORATIVE CENTER IN CONTROL SCIENCE...and amplify an internationally recognized center of excellence in control science research and education, through interaction between the faculty and

An optical method for characterizing carbon content in ceramic pot filters.

PubMed

Goodwin, J Y; Elmore, A C; Salvinelli, C; Reidmeyer, Mary R

2017-08-01

Ceramic pot filter (CPF) technology is a relatively common means of household water treatment in developing areas, and performance characteristics of CPFs have been characterized using production CPFs, experimental CPFs fabricated in research laboratories, and ceramic disks intended to be CPF surrogates. There is evidence that CPF manufacturers do not always fire their products according to best practices and the result is incomplete combustion of the pore forming material and the creation of a carbon core in the final CPFs. Researchers seldom acknowledge the existence of potential existence of carbon cores, and at least one CPF producer has postulated that the carbon may be beneficial in terms of final water quality because of the presence of activated carbon in consumer filters marketed in the Western world. An initial step in characterizing the presence and impact of carbon cores is the characterization of those cores. An optical method which may be more viable to producers relative to off-site laboratory analysis of carbon content has been developed and verified. The use of the optical method is demonstrated via preliminary disinfection and flowrate studies, and the results of these studies indicate that the method may be of use in studying production kiln operation.

Force supplementary comparison at SIM (SIM.M.F-S5), compression testing machines calibration, up to 200 kN

NASA Astrophysics Data System (ADS)

Cárdenas Moctezuma, A.; Torres Guzmán, J. C.

2016-01-01

CENAM, through the Force and Pressure Division, organized a comparison on testing machines calibration, in compression mode. The participating laboratories were SIM National Institutes of Metrology from Colombia, Peru and Costa Rica, where CENAM, Mexico was the pilot and reference laboratory. The results obtained by the laboratories are presented in this paper as well as the analysis of compatibility. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Post-Flight EDL Entry Guidance Performance of the 2011 Mars Science Laboratory Mission

NASA Technical Reports Server (NTRS)

Mendeck, Gavin F.; McGrew, Lynn Craig

2013-01-01

The 2011 Mars Science Laboratory was the first Mars guided entry which safely delivered the rover to a landing within a touchdown ellipse of 19.1 km x 6.9 km. The Entry Terminal Point Controller guidance algorithm is derived from the final phase Apollo Command Module guidance and, like Apollo, modulates the bank angle to control the range flown. The guided entry performed as designed without any significant exceptions. The Curiosity rover was delivered about 2.2 km from the expected touchdown. This miss distance is attributed to little time to correct the downrange drift from the final bank reversal and a suspected tailwind during heading alignment. The successful guided entry for the Mars Science Laboratory lays the foundation for future Mars missions to improve upon.

Rehabilitation of Executive Functions in a Real-Life Setting: Goal Management Training Applied to a Person with Schizophrenia

PubMed Central

Levaux, M.-N.; Larøi, F.; Malmedier, M.; Offerlin-Meyer, I.; Danion, J.-M.; Van der Linden, M.

2012-01-01

The aim was to assess the efficacy of a modified version of Goal Management Training (GMT) in a person with schizophrenia who had difficulties in attaining the final goal for new and multitasking daily-life situations. GMT is designed to improve abilities in establishing goal-directed plans and carrying them out effectively. Beneficial effects of GMT were measured for several clinical questionnaires, laboratory tasks, and three real-life situations: meal preparation (trained, familiar); washing (nontrained, familiar); meeting preparation (nontrained, unfamiliar). The results revealed improvement in planning and on trained laboratory and meal preparation tasks and a generalization of GMT effects on nontrained laboratory and everyday tasks. Self-esteem also improved. Finally, a two-year followup indicated the durability of the beneficial effects. PMID:23094177

Field trial of solvent-free emulsion in Oregon : final report.

DOT National Transportation Integrated Search

2003-03-01

This final report summarizes construction, laboratory and performance information gathered by ODOT personnel from a single field trial of solvent-free emulsion mix constructed in June 2001. The solvent-free emulsion mix presented several placement pr...

Final report on EUROMET key comparison EUROMET.M.D-K2 (EUROMET 627) "Comparison of density determinations of liquid samples"

NASA Astrophysics Data System (ADS)

Bettin, Horst; Heinonen, Martti; Gosset, André; Zelenka, Zoltán; Lorefice, Salvatore; Hellerud, Kristen; Durlik, Hanna; Jordaan, Werner; Field, Ireen

2016-01-01

The results of the key comparison EUROMET 627 (EUROMET.M.D-K2) are presented. This project covered the density measurements of three liquids: dodecane, water and an oil of high viscosity measured at 15 °C, 20 °C and 40 °C. Seven European metrology laboratories and the South African laboratory CSIR-NML (now: NMISA) measured the densities at atmospheric pressure by hydrostatic weighing of solid density standards between 04 October 2001 and 18 December 2001. The stability and homogeneity of the liquids were investigated by the pilot laboratory PTB. The results generally show good agreement among the participants. Only for the simple Mohr-Westphal balances do the uncertainties seem to be underestimated by the laboratories. Furthermore, the measurement of high-viscosity oil was difficult for some laboratories. Nevertheless, the five laboratories PTB/DE, BNM/FR (now: LNE/FR), OMH/HU (now: MKEH/HU), IMGC/IT (now: INRIM/IT) and GUM/PL agree with each other for stated uncertainties of 0.05 kg/m3 or less. This satisfies the current needs of customers who wish to calibrate or check liquid density measuring instruments such as oscillation-type density meters. No reference values were calculated since the subsequent CCM key comparison CCM.D-K2 had a different scope and the EUROMET 627 comparison was soon superseded by the EURAMET 1019 (EURAMET.M.D-K2) comparison. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

29 CFR 1910.7 - Definition and requirements for a nationally recognized testing laboratory.

Code of Federal Regulations, 2010 CFR

2010-07-01

... prejudice, at any time prior to the final decision by the Assistant Secretary in paragraph I.B.7.c. of this... writing by the close of the comment period. 6. Action after public comment—a. Final decision by Assistant... comment period. b. Public announcement. A copy of the Assistant Secretary's final decision will be...

Final report of APMP.QM-S6: clenbuterol in porcine meat

NASA Astrophysics Data System (ADS)

Sin, D. W.-M.; Ho, C.; Yip, Y.-C.

2016-01-01

At the CCQM Organic Analysis Working Group (OAWG) Meeting held in April 2012 and the APMP TCQM Meeting held in November 2012, an APMP supplementary comparison (APMP.QM-S6) on the determination of clenbuterol in porcine meat was supported by the OAWG and APMP TCQM. This comparison was organized by the Government Laboratory, Hong Kong. In order to accommodate a wider participation, a pilot study (APMP.QM-P22) was run in parallel to APMP.QM-S6. This study provided the means for assessing the measurement capabilities for determination of low-polarity measurands in a procedure that requires extraction, clean-up, analytical separation, and selective detection in a food matrix. A total of 7 institutes registered for the supplementary comparison and 6 of them submitted their results. 4 results were included for SCRV calculation. All participating laboratories applied Isotope Dilution Liquid Chromatography-Tandem Mass Spectrometry (ID-LCMS/MS) technique with clenbuterol-d9 as internal standard spiked for quantitation in this programme. KEY WORDS FOR SEARCH APMP.QM-S6 and Clenbuterol Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Assessment of Regional Explosion Discriminants Using Data Sets of Unparalleled Spatial Sampling

DTIC Science & Technology

2012-10-31

Air Force Research Laboratory AFRL ...Final Report APPROVED FOR PUBLIC RELEASE; DISTRIBUTION IS UNLIMITED. AIR FORCE RESEARCH LABORATORY Space Vehicles...Directorate 3550 Aberdeen Ave SE AIR FORCE MATERIEL COMMAND KIRTLAND AIR FORCE BASE, NM 87117-5776 Approved for public release; distribution

Magnetic Braking Revisited: Activities for the Undergraduate Laboratory

ERIC Educational Resources Information Center

Ireson, Gren; Twidle, John

2008-01-01

This paper revisits the demonstration of Lenz by dropping magnets down a non-magnetic tube. Recent publications are reviewed and ideas for undergraduate laboratory investigations are suggested. Finally, an example of matching theory to observation is presented. (Contains 4 tables, 5 figures and 3 footnotes.)

Graphite distortion ``C`` Reactor. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wood, N.H.

1962-02-08

This report covers the efforts of the Laboratory in an investigation of the graphite distortion in the ``C`` reactor at Hanford. The particular aspects of the problem to be covered by the Laboratory were possible ``fixes`` to the control rod sticking problem caused by VSR channel distortion.

Relationship of fatigue to the tensile stiffness of asphaltic concrete : final report on phase 1, laboratory investigation.

DOT National Transportation Integrated Search

1972-01-01

The correlation between asphaltic concrete tensile stiffness and fatigue life was determined in the laboratory. Constant strain fatigue tests were utilized and indirect tensile tests were selected because of their simplicity and applicability. Four a...

Sunscreen sun protection factor claim based on in vivo interlaboratory variability.

PubMed

Miksa, S; Lutz, D; Guy, C; Delamour, E

2016-12-01

The SPF (sun protection factor) is the best known reference in the world for expressing UVB protection. The SPF is used for labelling purposes for consumer guidance. The determination of the SPF is often accomplished using an in vivo method that has been standardized. Only one in vivo SPF value from one laboratory is required for claiming an SPF value. The aim of this study was to determine the relevance of the in vivo SPF value in terms of interlaboratory variability for claiming purposes and to determine whether some minimum number of different in vivo SPF values from different laboratories would improve the reliability of the final SPF claimed. A large population of 44 different commercially available sunscreen formulations from the European market has been investigated, covering various product types. The majority of the SPF values claimed ranged from 15 to 50+. For each product, at least three different in vivo SPF values tested in different laboratories have been gathered, and a variety of statistical analyses have been performed. For each SPF category from the average of all samples, the minimum and maximum in vivo-measured SPF values from the different laboratories would lead to labels claiming different levels of SPF for the same product. Indeed, with coefficients of variation for in vivo SPF determinations that exceed 50% in some cases, as an example, the same product could in reality be claimed to be SPF 30, SPF 50 or SPF 50+. In this study, the authors demonstrated that using only one in vivo SPF value from one laboratory may actually challenge the reliability of the final SPF claim significantly. To reduce the consumer health risk by ensuring the reliability of the SPF claim, an average from at least 3 (ideally 4) different in vivo SPF values should be compulsory. © 2016 Society of Cosmetic Scientists and the Société Française de Cosmétologie.

A New Approach to Standardize Multicenter Studies: Mobile Lab Technology for the German Environmental Specimen Bank

PubMed Central

Lermen, Dominik; Schmitt, Daniel; Bartel-Steinbach, Martina; Schröter-Kermani, Christa; Kolossa-Gehring, Marike; von Briesen, Hagen; Zimmermann, Heiko

2014-01-01

Technical progress has simplified tasks in lab diagnosis and improved quality of test results. Errors occurring during the pre-analytical phase have more negative impact on the quality of test results than errors encountered during the total analytical process. Different infrastructures of sampling sites can highly influence the quality of samples and therewith of analytical results. Annually the German Environmental Specimen Bank (ESB) collects, characterizes, and stores blood, plasma, and urine samples of 120–150 volunteers each on four different sampling sites in Germany. Overarching goal is to investigate the exposure to environmental pollutants of non-occupational exposed young adults combining human biomonitoring with questionnaire data. We investigated the requirements of the study and the possibility to realize a highly standardized sampling procedure on a mobile platform in order to increase the required quality of the pre-analytical phase. The results lead to the development of a mobile epidemiologic laboratory (epiLab) in the project “Labor der Zukunft” (future’s lab technology). This laboratory includes a 14.7 m2 reception area to record medical history and exposure-relevant behavior, a 21.1 m2 examination room to record dental fillings and for blood withdrawal, a 15.5 m2 biological safety level 2 laboratory to process and analyze samples on site including a 2.8 m2 personnel lock and a 3.6 m2 cryofacility to immediately freeze samples. Frozen samples can be transferred to their final destination within the vehicle without breaking the cold chain. To our knowledge, we herewith describe for the first time the implementation of a biological safety laboratory (BSL) 2 lab and an epidemiologic unit on a single mobile platform. Since 2013 we have been collecting up to 15.000 individual human samples annually under highly standardized conditions using the mobile laboratory. Characterized and free of alterations they are kept ready for retrospective analyses in their final archive, the German ESB. PMID:25141120

A new approach to standardize multicenter studies: mobile lab technology for the German Environmental Specimen Bank.

PubMed

Lermen, Dominik; Schmitt, Daniel; Bartel-Steinbach, Martina; Schröter-Kermani, Christa; Kolossa-Gehring, Marike; von Briesen, Hagen; Zimmermann, Heiko

2014-01-01

Technical progress has simplified tasks in lab diagnosis and improved quality of test results. Errors occurring during the pre-analytical phase have more negative impact on the quality of test results than errors encountered during the total analytical process. Different infrastructures of sampling sites can highly influence the quality of samples and therewith of analytical results. Annually the German Environmental Specimen Bank (ESB) collects, characterizes, and stores blood, plasma, and urine samples of 120-150 volunteers each on four different sampling sites in Germany. Overarching goal is to investigate the exposure to environmental pollutants of non-occupational exposed young adults combining human biomonitoring with questionnaire data. We investigated the requirements of the study and the possibility to realize a highly standardized sampling procedure on a mobile platform in order to increase the required quality of the pre-analytical phase. The results lead to the development of a mobile epidemiologic laboratory (epiLab) in the project "Labor der Zukunft" (future's lab technology). This laboratory includes a 14.7 m(2) reception area to record medical history and exposure-relevant behavior, a 21.1 m(2) examination room to record dental fillings and for blood withdrawal, a 15.5 m(2) biological safety level 2 laboratory to process and analyze samples on site including a 2.8 m(2) personnel lock and a 3.6 m2 cryofacility to immediately freeze samples. Frozen samples can be transferred to their final destination within the vehicle without breaking the cold chain. To our knowledge, we herewith describe for the first time the implementation of a biological safety laboratory (BSL) 2 lab and an epidemiologic unit on a single mobile platform. Since 2013 we have been collecting up to 15.000 individual human samples annually under highly standardized conditions using the mobile laboratory. Characterized and free of alterations they are kept ready for retrospective analyses in their final archive, the German ESB.

Observations of the Performance of the U.S. Laboratory Architecture

NASA Technical Reports Server (NTRS)

Jones, Rod

2002-01-01

The United States Laboratory Module "Destiny" was the product of many architectural, technology, manufacturing, schedule and cost constraints which spanned 15 years. Requirements for the Space Station pressurized elements were developed and baselined in the mid to late '80's. Although the station program went through several design changes the fundamental requirements that drove the architecture did not change. Manufacturing of the U.S. Laboratory began in the early 90's. Final assembly and checkout testing completed in December of 2000. Destiny was launched, mated to the International Space Station and successfully activated on the STS-98 mission in February of 2001. The purpose of this paper is to identify key requirements, which directly or indirectly established the architecture of the U.S. Laboratory. Provide an overview of how that architecture affected the manufacture, assembly, test, and activation of the module on-orbit. And finally, through observations made during the last year of operation, provide considerations in the development of future requirements and mission integration controls for space habitats.

Student assessment of the educational benefits of using a CD-ROM for instruction of basic surgical skills.

PubMed

Howe, Lisa M; Boothe, Harry W; Hartsfield, Sandee M

2005-01-01

At Texas A&M University, introductory-level surgical lecture and laboratory notes were converted to a CD-ROM format that included illustrative photographs as well as instructional videos demonstrating the basic surgical skills that all students were required to master. The CD-ROM was distributed to all students in place of traditional paper notes in the second-year surgical class in the professional veterinary curriculum. The study reported here was designed to evaluate the educational benefits of the use of the CD-ROM in place of traditional paper notes by examining the attitudes and practices of students before and after exposure to the CD-ROM format. An anonymous survey was distributed to students in the second-year introductory surgery course on the first day of class and again on the last day of class. Responses to questions were tabulated, response frequencies determined, and Chi-square analysis performed to determine differences between initial and final responses. On the final survey, 89 per cent of students responded that the instructional videos definitely helped them prepare for the laboratory, and 77 per cent responded that they were more likely to practice techniques learned from the CD-ROM videos than those learned from traditional study materials. The majority of students believed that the CD-ROM improved both the course (60 per cent) and their learning experience (62 per cent) as compared to traditional paper notes. Including instructional videos on the CD-ROM enhanced the educational experience of the students by promoting preparedness for laboratories and promoting practice of techniques learned from the videos outside of the laboratory.

Final report on EURAMET.QM-S10/1274: supplementary comparison of preparative capabilities for automotive gas mixtures

NASA Astrophysics Data System (ADS)

Val'ková, M.; Ďurišová, Z.; Szilágyi, Z. N.; Büki, T.; Fükű, J.

2016-01-01

This bilateral supplementary preparative comparison involves standard gas mixtures of automotive gas containing carbon monoxide, carbon dioxide and propane in nitrogen. Two laboratories (SMU, Slovakia and MKEH, Hungary) participated in this supplementary comparison. SMU was the coordinating laboratory, responsible for collecting and reporting measurement results. The participants have established facilities for automotive gas gravimetric preparation and analysis. The agreement of the results in this supplementary comparison is good. All the results with their reported uncertainties are in agreement with the reference values for the participants. SMU participated and obtained good results in the previous preparative comparison organised within EURAMET in this field. Both laboratories have existing claims for their Calibration and Measurement Capabilities (CMCs) for automotive gas mixtures. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Plasmid fermentation process for DNA immunization applications.

PubMed

Carnes, Aaron E; Williams, James A

2014-01-01

Plasmid DNA for immunization applications must be of the highest purity and quality. The ability of downstream purification to efficiently produce a pure final product is directly influenced by the performance of the upstream fermentation process. While several clinical manufacturing facilities already have validated fermentation processes in place to manufacture plasmid DNA for use in humans, a simple and inexpensive laboratory-scale fermentation process can be valuable for in-house production of plasmid DNA for use in animal efficacy studies. This chapter describes a simple fed-batch fermentation process for producing bacterial cell paste enriched with high-quality plasmid DNA. A constant feeding strategy results in a medium cell density culture with continuously increasing plasmid amplification towards the end of the process. Cell banking and seed culture preparation protocols, which can dramatically influence final product yield and quality, are also described. These protocols are suitable for production of research-grade plasmid DNA at the 100 mg-to-1.5 g scale from a typical 10 L laboratory benchtop fermentor.

Environmental and Ecology Branch Progress Report, 1974 through 1976 Volume 2

DTIC Science & Technology

1978-06-01

nitrogen wastes generated by manufacture of Army explosives have been studied with reqard to aeration rates, residence times, nutrient requirements...STATES ...... ....... .......................... .. 18 vii BIOLOGICAL TREATMENT OF EXPLOSIVE WASTES ..... ............. ... 19 BIOLOGICAL AEROSOLS...1976, and the information was forwarded to Chemical Systems Laboratory for inclusion in the final report to ERDA. 13 BIOLOGICAL TREATMENT OF EXPLOSIVE

NRC/AMRMC Resident Research Associateship Program

DTIC Science & Technology

2013-03-01

l) Intravital Microscopy was successfully employed for investigating EG sheddÍng in hemorrhagic shock/resuscitation for the very first time; 2... Intravital microscopy integrated with systemic hemodynamics evaluations may be essential and more accurate tools to identify changes and study mechanisms...Glycocalyx during Hemorrhagic Shock in Rats using Intravital Microscopy. Submitted to Microvascular Research, 2012 (under review). FINAL REPORT Laboratory

Waterfowl of the Savannah River Plant: Comprehensive cooling water study. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mayer, J.J.; Kennamer, R.A.; Hoppe, R.T.

1986-06-01

Thirty-one species of waterfowl have been documented on the Savannah River Plant (SPR). The Savannah River Ecology Laboratory (SREL) has been conducting waterfowl research on the site for the past 15 years. This research has included work on waterfowl utilization of the SRP, wood duck reproductive biology, and waterfowl wintering ecology. Results are described.

TECHNOLOGY TRANSFER OF AN INNOVATIVE REMEDIATION TECHNOLOGY FROM THE LABORATORY TO THE FIELD: A CASE STUDY OF IN SITU AEROBIC COMETABOLIC BIOREMEDIATION. (R825689C067)

EPA Science Inventory

The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Concl...

Joint research effort on vibrations of twisted plates, phase 1: Final results

NASA Technical Reports Server (NTRS)

Kielb, R. E.; Leissa, A. W.; Macbain, J. C.; Carney, K. S.

1985-01-01

The complete theoretical and experimental results of the first phase of a joint government/industry/university research study on the vibration characteristics of twisted cantilever plates are given. The study is conducted to generate an experimental data base and to compare many different theoretical methods with each other and with the experimental results. Plates with aspect ratios, thickness ratios, and twist angles representative of current gas turbine engine blading are investigated. The theoretical results are generated by numerous finite element, shell, and beam analysis methods. The experimental results are obtained by precision matching a set of twisted plates and testing them at two laboratories. The second and final phase of the study will concern the effects of rotation.

Former Soviet Republic Capabilities in Space and Science

DTIC Science & Technology

1993-02-01

Antonino Zichichi (Italy). ,-■«_• World Laboratory has established en annual prize of Erice "Science for Peace . The prize fund amounted to $1 100 000...instabilities and vulnerabilities to terrorism. Finally, Prof. Antonino Zichichi, President of the World Laboratory, reviewed the efforts he has...collaboration with the World Laboratory and under the auspices of the Presidency of the Council of Ministers of Italy 99 Antonino ZICHICHI - Chairman

First-year Engineering Education with the Creative Electrical Engineering Laboratory

NASA Astrophysics Data System (ADS)

Tsukamoto, Takehiko; Sugito, Tetsumasa; Ozeki, Osamu; Ushiroda, Sumio

The Department of Electrical and Electronic Engineering in Toyota National College of Technology has put great emphasis on fundamental subjects. We introduced the creative electrical engineering laboratory into the first-year engineering education since 1998. The laboratory concentrates on the practice exercise. The final questionnaire of students showed that our first-year education is very effective to promote students motivation and their scholastic ability in engineering.

Implementing the Science Assessment Standards: Developing and validating a set of laboratory assessment tasks in high school biology

NASA Astrophysics Data System (ADS)

Saha, Gouranga Chandra

Very often a number of factors, especially time, space and money, deter many science educators from using inquiry-based, hands-on, laboratory practical tasks as alternative assessment instruments in science. A shortage of valid inquiry-based laboratory tasks for high school biology has been cited. Driven by this need, this study addressed the following three research questions: (1) How can laboratory-based performance tasks be designed and developed that are doable by students for whom they are designed/written? (2) Do student responses to the laboratory-based performance tasks validly represent at least some of the intended process skills that new biology learning goals want students to acquire? (3) Are the laboratory-based performance tasks psychometrically consistent as individual tasks and as a set? To answer these questions, three tasks were used from the six biology tasks initially designed and developed by an iterative process of trial testing. Analyses of data from 224 students showed that performance-based laboratory tasks that are doable by all students require careful and iterative process of development. Although the students demonstrated more skill in performing than planning and reasoning, their performances at the item level were very poor for some items. Possible reasons for the poor performances have been discussed and suggestions on how to remediate the deficiencies have been made. Empirical evidences for validity and reliability of the instrument have been presented both from the classical and the modern validity criteria point of view. Limitations of the study have been identified. Finally implications of the study and directions for further research have been discussed.

A FEASIBILITY STUDY TO INVESTIGATE THE INSTRUMENTATION, ESTABLISHMENT, AND OPERATION OF A LEARNING LABORATORY FOR HARD-OF-HEARING CHILDREN, FINAL REPORT.

ERIC Educational Resources Information Center

STEPP, ROBERT E.

TEN CHILDREN AGED 5-8 WERE SELECTED TO TEST A SELF-INSTRUCTIONAL, SELF-OPERATING SYSTEM TO DEVELOP LIPREADING SKILLS. THEIR HEARING DEFICIENCY RANGED FROM HARD OF HEARING TO PROFOUNDLY DEAF. THE SYSTEM CONSISTED OF THREE STUDY CARRELS, AN 8-MM CARTRIDGE-LOADING SOUND MOTION PICTURE PROJECTOR, AND AN OBSERVATION BOOTH UTILIZING A ONE-WAY MIRROR.…

Reactions of Thiocyanate Ions with Acid: A Laboratory Experiment.

ERIC Educational Resources Information Center

Glidewell, Christopher; And Others

1984-01-01

Background information, procedures, and typical results are provided for a three-part experiment involving reactions of potassium thiocynate (KNCS) with sulfuric acid. The experiment represents the final stage of structured work prior to students' research projects during their final year. (JM)

Laboratory and Theoretical Studies of Tropospheric Iodine Chemistry (Invited)

NASA Astrophysics Data System (ADS)

Plane, J. M.; Saunders, R. W.; Kumar, R.; Gomez Martin, J.; Mahajan, A. S.; Murray, B. J.

2009-12-01

This paper will discuss progress in understanding two important properties of iodine in the marine boundary layer: ozone depletion and new particle formation. A variety of laboratory techniques have been employed to study the kinetics and growth of iodine oxide particles, their uptake of water, sulphuric and organic acids, and the recyling of iodine from them. The photochemistry of a variety of iodine oxides, which are central to catalytic O3 depletion and are involved in homogeneous condensation, will also be described. The use of high-level quantum chemistry calculations to underpin these experiments will then be discussed. Finally, the implications of this work for understanding the impact of iodine in both remote and polluted marine environments will be considered.

Miniature infrared data acquisition and telemetry system

NASA Technical Reports Server (NTRS)

Stokes, J. H.; Ward, S. M.

1985-01-01

The Miniature Infrared Data Acquisition and Telemetry (MIRDAT) Phase 1 study was performed to determine the technical and commercial feasibility of producing a miniaturized electro-optical telemetry system. This system acquires and transmits experimental data from aircraft scale models for realtime monitoring in wind tunnels. During the Phase 1 study, miniature prototype MIRDAT telemetry devices were constructed, successfully tested in the laboratory and delivered to the user for wind tunnel testing. A search was conducted for commercially available components and advanced hybrid techniques to further miniaturize the system during Phase 2 development. A design specification was generated from laboratory testing, user requirements and discussions with component manufacturers. Finally, a preliminary design of the proposed MIRDAT system was documented for Phase 2 development.

Biophotonics Master studies: teaching and training experience at University of Latvia

NASA Astrophysics Data System (ADS)

Spigulis, Janis

2007-06-01

Two-year program for Master's studies on Biophotonics (Biomedical Optics) has been originally developed and carried out at University of Latvia since 1995. The Curriculum contains basic subjects like Fundamentals of Biomedical Optics, Medical Lightguides, Anatomy and Physiology, Lasers and Non-coherent Light Sources, Basic Physics, etc. Student laboratories, special English Terminology and Laboratory-Clinical Praxis are also involved as the training components, and Master project is the final step for the degree award. Life-long learning is supported by several E-courses and an extensive short course for medical laser users "Lasers and Bio-optics in Medicine". Recently a new inter-university European Social Fund project was started to adapt the program accordingly to the Bologna Declaration guidelines.

Attitudes of medical laboratory technology graduates towards the internship training period at king faisal university.

PubMed

Bashawri, Layla A M; Ahmed, Mirghani A; Bahnassy, Ahmed A L; Al-Salim, Jawaher A

2006-05-01

The objective of this present survey was to look into the attitudes of medical laboratory technology (MLT) graduates towards the internship training period of the MLT Department, College of Applied Medical Sciences, King Faisal University. A self-administered questionnaire was designed and distributed for this purpose. The study period was from December 1(st) 2002 - 31(st) December 2004. Two-hundred questionnaires were distributed to recent graduates, and 115 were returned completed. All respondents agreed with the importance and necessity of the internship period, and felt it should not be reduced or eliminated. The most favorite laboratory where they liked to work was microbiology (70%). They all agreed that evaluation report with hospital staff and laboratory set up were vital in achieving the goals of the internship period. The majority stressed the significance of safety precautions and the application of theoretical knowledge before performing technical assignments. The respondents had very positive attitudes towards the internship-training period stressing its importance. The most favorite laboratory rotations were in rank order: Microbiology, Serology followed by Histotechnology, Hematology, Blood Banking and finally Clinical Chemistry. The majority of graduates had a very positive attitude also towards medical laboratory technology as a profession.

Final report on key comparison EURAMET.M.P-K13 in the range 50 MPa to 500 MPa of hydraulic gauge pressure

NASA Astrophysics Data System (ADS)

Kocas, I.; Sabuga, W.; Bergoglio, M.; Eltaweel, A.; Korasie, C.; Farar, P.; Setina, J.; Waller, B.; Durgut, Y.

2015-01-01

The regional key comparison EURAMET.M.P-K13 for pressure measurements in liquid media from 50 MPa to 500 MPa was piloted by the TÜBİTAK UME Pressure Group Laboratories, Turkey. The transfer standard was a DH-Budenberg pressure balance with a free deformation piston-cylinder unit of 2 mm2 nominal effective area. Six laboratories from the EURAMET region, namely PTB, INRIM, SMU, IMT, NPL and UME, and two laboratories from the AFRIMETS region, NIS and NMISA participated in this comparison. Participant laboratories and countries are given in the bottom of the page. PTB participated in this comparison to provide a link to corresponding 500 MPa CCM key comparison CCM.P-K13. The results of all participants excepting NMISA and NPL were found to be consistent with the reference value of the actual comparison and of CCM.P-K13 within their claimed uncertainties (k = 2), at all pressures. Compared in pairs all laboratories with exception of NPL and NMISA demonstrate their agreement with each other within the expanded uncertainties (k = 2) at all pressures. The results are therefore considered to be satisfactory. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Results of the EURAMET.RI(II)-S6.I-129 supplementary comparison

NASA Astrophysics Data System (ADS)

García-Toraño, Eduardo; Altzitzoglou, Timotheos; Auerbach, Pavel; Bé, Marie-Martine; Lourenço, Valérie; Bobin, Christophe; Cassette, Philippe; Dersch, Rainer; Kossert, Karsten; Nähle, Ole; Peyrés, Virginia; Pommé, Stefaan; Rozkov, Andrej; Sanchez-Cabezudo, Anabel; Sochoro&vacute; , Jana

2015-01-01

An international comparison of the long-lived gamma-ray emitter 129I has been recently completed. A total of 5 laboratories measured a solution prepared by Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT). Aliquots of the master solution were standardized in terms of activity per mass unit by participant laboratories using 4 different techniques. The results of the comparison can be used as the basis for establishing the equivalence among the laboratories. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Reducing cognitive load in the chemistry laboratory by using technology-driven guided inquiry experiments

NASA Astrophysics Data System (ADS)

Hubacz, Frank, Jr.

The chemistry laboratory is an integral component of the learning experience for students enrolled in college-level general chemistry courses. Science education research has shown that guided inquiry investigations provide students with an optimum learning environment within the laboratory. These investigations reflect the basic tenets of constructivism by engaging students in a learning environment that allows them to experience what they learn and to then construct, in their own minds, a meaningful understanding of the ideas and concepts investigated. However, educational research also indicates that the physical plant of the laboratory environment combined with the procedural requirements of the investigation itself often produces a great demand upon a student's working memory. This demand, which is often superfluous to the chemical concept under investigation, creates a sensory overload or extraneous cognitive load within the working memory and becomes a significant obstacle to student learning. Extraneous cognitive load inhibits necessary schema formation within the learner's working memory thereby impeding the transfer of ideas to the learner's long-term memory. Cognitive Load Theory suggests that instructional material developed to reduce extraneous cognitive load leads to an improved learning environment for the student which better allows for schema formation. This study first compared the cognitive load demand, as measured by mental effort, experienced by 33 participants enrolled in a first-year general chemistry course in which the treatment group, using technology based investigations, and the non-treatment group, using traditional labware, investigated identical chemical concepts on five different exercises. Mental effort was measured via a mental effort survey, a statistical comparison of individual survey results to a procedural step count, and an analysis of fourteen post-treatment interviews. Next, a statistical analysis of achievement was completed by comparing lab grade averages, final exam averages, and final course grade averages between the two groups. Participant mental effort survey results showed significant positive effects of technology in reducing cognitive load for two laboratory investigations. One investigation revealed a significant difference in achievement measured by lab grade average comparisons. Although results of this study are inconclusive as to the usefulness of technology-driven investigations to affect learning, recommendations for further study are discussed.

Final report on SIM.T-S5: comparison of the calibration of 100 Ω platinum resistance thermometers

NASA Astrophysics Data System (ADS)

del Campo, D.; García, S.; Velasquez, A.; Medrano, J. A.; Solano, A.; Torres, H. E.

2015-01-01

An International Comparison on industrial Platinum Resistance Thermometers (PRTs) among the National Metrology Institutes (NMIs) of Spain, Panama, Honduras, El Salvador, Costa Rica and Nicaragua began in 2013 and was successfully completed in 2014. Two PRTs were circulated (hand carried) and compared in the range from -38.8 °C up to 250 °C. The Centro Español de Metrología (Spanish NMI), CEM, acted as the pilot laboratory providing the reference value of the comparison. The thermometers have shown an acceptable behavior throughout the comparison, therefore the results can be considered valid for comparing the measurement capabilities of the participant laboratories. The equivalence between the participant laboratories in the calibration of platinum resistance thermometers by comparison in the range from -38,8 °C up to 250 °C has been demonstrated in almost all cases. This report presents the results of this comparison and provides detailed information of the measurements performed by the participating laboratories. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCT, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

United States Air Force Summer Research Program -- 1993. Volume 16. Arnold Engineering Development Center. Frank J. Seiler Research Laboratory. Wilford Hall Medical Center

DTIC Science & Technology

1993-12-01

A I 7f t UNITED STATE AIR FORCE SUMMER RESEARCH PROGRAM -- 1993 SUMMER RESEARCH PROGRAM FINAL REPORTS VOLUME 16 ARNOLD ENGINEERING DEVELOPMENT CENTER...FRANK J. SELLER RESEARCH LABORATORY WILFORD HALL MEDICAL CENTER RESEARCH & DEVELOPMENT LABORATORIES 5800 Uplander Way Culver City, CA 90230-6608...National Rd. Vol-Page No: 15-44 Dist Tecumseh High School 8.4 New Carlisle, OH 45344-0000 Barber, Jason Laboratory: AL/CF 1000 10th St. Vol-Page No

Development of Facilities for an Ocean Engineering Laboratory. Final Report.

ERIC Educational Resources Information Center

Nash, W. A.; And Others

A collection of seven laboratory facilities and processes dedicated to improving student understanding of the fundamental concepts associated with the structural mechanics of oceanic structures is described. Complete working drawings covering all mechanical and electrical aspects of these systems are presented so that the systems may be reproduced…

European validation of Real-Time PCR method for detection of Salmonella spp. in pork meat.

PubMed

Delibato, Elisabetta; Rodriguez-Lazaro, David; Gianfranceschi, Monica; De Cesare, Alessandra; Comin, Damiano; Gattuso, Antonietta; Hernandez, Marta; Sonnessa, Michele; Pasquali, Frédérique; Sreter-Lancz, Zuzsanna; Saiz-Abajo, María-José; Pérez-De-Juan, Javier; Butrón, Javier; Prukner-Radovcic, Estella; Horvatek Tomic, Danijela; Johannessen, Gro S; Jakočiūnė, Džiuginta; Olsen, John E; Chemaly, Marianne; Le Gall, Francoise; González-García, Patricia; Lettini, Antonia Anna; Lukac, Maja; Quesne, Segolénè; Zampieron, Claudia; De Santis, Paola; Lovari, Sarah; Bertasi, Barbara; Pavoni, Enrico; Proroga, Yolande T R; Capuano, Federico; Manfreda, Gerardo; De Medici, Dario

2014-08-01

The classical microbiological method for detection of Salmonella spp. requires more than five days for final confirmation, and consequently there is a need for an alternative methodology for detection of this pathogen particularly in those food categories with a short shelf-life. This study presents an international (at European level) ISO 16140-based validation study of a non-proprietary Real-Time PCR-based method that can generate final results the day following sample analysis. It is based on an ISO compatible enrichment coupled to an easy and inexpensive DNA extraction and a consolidated Real-Time PCR assay. Thirteen laboratories from seven European Countries participated to this trial, and pork meat was selected as food model. The limit of detection observed was down to 10 CFU per 25 g of sample, showing excellent concordance and accordance values between samples and laboratories (100%). In addition, excellent values were obtained for relative accuracy, specificity and sensitivity (100%) when the results obtained for the Real-Time PCR-based methods were compared to those of the ISO 6579:2002 standard method. The results of this international trial demonstrate that the evaluated Real-Time PCR-based method represents an excellent alternative to the ISO standard. In fact, it shows an equal and solid performance as well as it reduces dramatically the extent of the analytical process, and can be easily implemented routinely by the Competent Authorities and Food Industry laboratories. Copyright © 2014 Elsevier B.V. All rights reserved.

Role of Skill Laboratory Training in Medical Education - Students’ Perspective.

PubMed

Hashim, Rizwan; Qamar, Khadija; Khan, Muhammad Alamgir; Rehman, Sabah

2016-03-01

To evaluate the perceptions of medical students regarding their training utilizing facilities provided in the skill laboratory of a public sector medical college. Cross-sectional study. Army Medical College, Rawalpindi, from October to December 2014. Students of final year MBBS who had underwent skill laboratory training were recruited through convenience purposive sampling. Students not exposed to skill laboratory training were excluded. Data collection tool was a questionnaire having 23 questions with responses on Likert Scale as strongly disagree, disagree, agree and strongly agree coded as 1, 2, 3 and 4, respectively. Data was analysed on SPSS version 22. There were 78 (57%) male and 59 (43%) female students out of 137, with mean age of 22.59 ±0.74 years. The response rate was 68.5%. Cronbach's Alpha test was 0.84 showing high reliability. The mean of sum of all the 23 items was 63.85 ±8.71, whereas item means was 2.78 ±0.38, reflecting a high inclination of students towards skill laboratory training. Frequency of students responding in favour of skill laboratory training was significantly high (p < 0.05). Medical students perceived skill laboratory training as a favoured learning strategy as compared to practising on real patients for acquisition of various aspects of clinical skills, knowledge and attitude.

Neither Single nor a Combination of Routine Laboratory Parameters can Discriminate between Gram-positive and Gram-negative Bacteremia

PubMed Central

Ratzinger, Franz; Dedeyan, Michel; Rammerstorfer, Matthias; Perkmann, Thomas; Burgmann, Heinz; Makristathis, Athanasios; Dorffner, Georg; Loetsch, Felix; Blacky, Alexander; Ramharter, Michael

2015-01-01

Adequate early empiric antibiotic therapy is pivotal for the outcome of patients with bloodstream infections. In clinical practice the use of surrogate laboratory parameters is frequently proposed to predict underlying bacterial pathogens; however there is no clear evidence for this assumption. In this study, we investigated the discriminatory capacity of predictive models consisting of routinely available laboratory parameters to predict the presence of Gram-positive or Gram-negative bacteremia. Major machine learning algorithms were screened for their capacity to maximize the area under the receiver operating characteristic curve (ROC-AUC) for discriminating between Gram-positive and Gram-negative cases. Data from 23,765 patients with clinically suspected bacteremia were screened and 1,180 bacteremic patients were included in the study. A relative predominance of Gram-negative bacteremia (54.0%), which was more pronounced in females (59.1%), was observed. The final model achieved 0.675 ROC-AUC resulting in 44.57% sensitivity and 79.75% specificity. Various parameters presented a significant difference between both genders. In gender-specific models, the discriminatory potency was slightly improved. The results of this study do not support the use of surrogate laboratory parameters for predicting classes of causative pathogens. In this patient cohort, gender-specific differences in various laboratory parameters were observed, indicating differences in the host response between genders. PMID:26522966

Generation of neutral and high-density electron–positron pair plasmas in the laboratory

PubMed Central

Sarri, G.; Poder, K.; Cole, J. M.; Schumaker, W.; Di Piazza, A.; Reville, B.; Dzelzainis, T.; Doria, D.; Gizzi, L. A.; Grittani, G.; Kar, S.; Keitel, C. H.; Krushelnick, K.; Kuschel, S.; Mangles, S. P. D.; Najmudin, Z.; Shukla, N.; Silva, L. O.; Symes, D.; Thomas, A. G. R.; Vargas, M.; Vieira, J.; Zepf, M.

2015-01-01

Electron–positron pair plasmas represent a unique state of matter, whereby there exists an intrinsic and complete symmetry between negatively charged (matter) and positively charged (antimatter) particles. These plasmas play a fundamental role in the dynamics of ultra-massive astrophysical objects and are believed to be associated with the emission of ultra-bright gamma-ray bursts. Despite extensive theoretical modelling, our knowledge of this state of matter is still speculative, owing to the extreme difficulty in recreating neutral matter–antimatter plasmas in the laboratory. Here we show that, by using a compact laser-driven setup, ion-free electron–positron plasmas with unique characteristics can be produced. Their charge neutrality (same amount of matter and antimatter), high-density and small divergence finally open up the possibility of studying electron–positron plasmas in controlled laboratory experiments. PMID:25903920

Generation of neutral and high-density electron-positron pair plasmas in the laboratory.

PubMed

Sarri, G; Poder, K; Cole, J M; Schumaker, W; Di Piazza, A; Reville, B; Dzelzainis, T; Doria, D; Gizzi, L A; Grittani, G; Kar, S; Keitel, C H; Krushelnick, K; Kuschel, S; Mangles, S P D; Najmudin, Z; Shukla, N; Silva, L O; Symes, D; Thomas, A G R; Vargas, M; Vieira, J; Zepf, M

2015-04-23

Electron-positron pair plasmas represent a unique state of matter, whereby there exists an intrinsic and complete symmetry between negatively charged (matter) and positively charged (antimatter) particles. These plasmas play a fundamental role in the dynamics of ultra-massive astrophysical objects and are believed to be associated with the emission of ultra-bright gamma-ray bursts. Despite extensive theoretical modelling, our knowledge of this state of matter is still speculative, owing to the extreme difficulty in recreating neutral matter-antimatter plasmas in the laboratory. Here we show that, by using a compact laser-driven setup, ion-free electron-positron plasmas with unique characteristics can be produced. Their charge neutrality (same amount of matter and antimatter), high-density and small divergence finally open up the possibility of studying electron-positron plasmas in controlled laboratory experiments.

State of laboratory manual instruction in California community college introductory (non-majors) biology laboratory instruction

NASA Astrophysics Data System (ADS)

Priest, Michelle

College students must complete a life science course prior to graduation for a bachelor's degree. Generally, the course has lecture and laboratory components. It is in the laboratory where there are exceptional opportunities for exploration, challenge and application of the material learned. Optimally, this would utilize the best of inquiry based approaches. Most community colleges are using a home-grown or self written laboratory manual for the direction of work in the laboratory period. Little was known about the motivation, development and adaptation of use. It was also not known about the future of the laboratory manuals in light of the recent learning reform in California Community Colleges, Student Learning Outcomes. Extensive interviews were conducted with laboratory manual authors to determine the motivation, process of development, who was involved and learning framework used in the creation of the manuals. It was further asked of manual authors their ideas about the future of the manual, the development of staff and faculty and finally, the role Student Learning Outcomes would play in the manual. Science faculty currently teaching the non-majors biology laboratories for at least two semesters were surveyed on-line about actual practice of the manual, assessment, manual flexibility, faculty training and incorporation of Student Learning Outcomes. Finally, an evaluation of the laboratory manual was done using an established Laboratory Task Analysis Instrument. Laboratory manuals were evaluated on a variety of categories to determine the level of inquiry instruction done by students in the laboratory section. The results were that the development of homegrown laboratory manuals was done by community colleges in the Los Angeles and Orange Counties in an effort to minimize the cost of the manual to the students, to utilize all the exercises in a particular lab and to effectively utilize the materials already owned by the department. Further, schools wanted to utilize the current faculty research expertise and knowledge. Unfortunately, laboratory manual authors had no real learning framework in the development of the manual. Based on the LAI, most manuals focused on the lowest levels of inquiry based instruction. Most manuals focused exercises on cell and molecular topics. The manuals had little student exploration, creation or design in the laboratory exercise and no option for repeating the exercise. There was a clear desire of faculty and authors to improve the laboratory experience and manual. Authors and faculty wished to include more inquiry and utilize the best of Student Learning Outcome (SLO) methodologies. Authors and the laboratory manuals have a major disconnect in that authors have clear desires inquiry based learning for the manual but do not effectively implement the inquiry based learning for various reasons. The manuals themselves, laboratory manuals themselves are not robust inquiry based learning models to maximize student learning. Authors and faculty are disconnected in that authors know what they want their manuals to do...but do not effectively communicate that to faculty. Finally, schools are in a "wait and see" approach as to when to integrate the latest learning theory mandated by the Chancellors Office -- Student Learning Outcomes.

USAF Development Of Optical Correlation Missile Guidance

NASA Astrophysics Data System (ADS)

Kaehr, Ronald; Spector, Marvin

1980-12-01

In 1965, the Advanced Development Program (ADP)-679A of the Avionics Laboratory initiated development of guidance systems for stand-off tactical missiles. Employing project engineering support from the Aeronautical Systems Division, WPAFB, the Avionics Laboratory funded multiple terminal guidance concepts and related midcourse navigation technology. Optical correlation techniques which utilize prestored reference information for autonomous target acquisition offered the best near-term opportunity for meeting mission goals. From among the systems studied and flight tested, Aimpoint* optical area guidance provided the best and most consistent performance. Funded development by the Air Force ended in 1974 with a MK-84 guided bomb drop test demonstration at White Sands Missile Range and the subsequent transfer of the tactical missile guidance development charter to the Air Force Armament Laboratory, Eglin AFB. A historical review of optical correlation development within the Avionics Laboratory is presented. Evolution of the Aimpoint system is specifically addressed. Finally, a brief discussion of trends in scene matching technology is presented.

ESTABLISHMENT OF AN ENVIRONMENTAL CONTROL TECHNOLOGY LABORATORY WITH A CIRCULATING FLUIDIZED-BED COMBUSTION SYSTEM

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wei-Ping Pan; Andy Wu; John T. Riley

This report is to present the progress made on the project ''Establishment of an Environmental Control Technology Laboratory (ECTL) with a Circulating Fluidized-Bed Combustion (CFBC) System'' during the period October 1, 2004 through December 31, 2004. The following tasks have been completed. First, the renovation of the new Combustion Laboratory and the construction of the Circulating Fluidized-Bed (CFB) Combustor Building have proceeded well. Second, the detailed design of supporting and hanging structures for the CFBC was completed. Third, the laboratory-scale simulated fluidized-bed facility was modified after completing a series of pretests. The two problems identified during the pretest were solved.more » Fourth, the carbonization of chicken waste and coal was investigated in a tube furnace and a Thermogravimetric Analyzer (TGA). The experimental results from this study are presented in this report. Finally, the proposed work for the next quarter has been outlined in this report.« less

Project Final Report: The Institute for Sustained Performance, Energy, and Resilience (SUPER)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hollingsworth, Jeffrey K.

This project concentrated on various aspects of creating and applying tool infrastructure to make it easier to effectively use large-scale parallel computers. This project was collaborative with Argonne National Laboratory, Lawrence Berkeley National Laboratory, Lawrence Livermore National Laboratory, Oak Ridge National Laboratory, U.C. San Diego, University of Maryland, University of North Carolina, University of Oregon, University Southern California, University of Tennessee, and University of Utah. The research conducted during this project at the University of Maryland is summarized in this report. The complete details of the work are available in the publications listed at the end of the report. Manymore » of the concepts created during this project have been incorporated into tools and made available as freely downloadable software (www.dyninst.org/harmony). It also supported the studies of six graduate students, one undergraduate student, and two post-docs. The funding also provided summer support for the PI and part of the salary of a research staff member.« less

Final Progress Report for Ionospheric Dusty Plasma In the Laboratory [Smokey Plasma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robertson, Scott

2010-07-31

“Ionospheric Dusty Plasma in the Laboratory” is a research project with the purpose of finding and reproducing the characteristics of plasma in the polar mesosphere that is unusually cold (down to 140 K) and contains nanometer-sized dust particles. This final progress report summarizes results from four years of effort that include a final year with a no-cost extension.

Characterization of flaws in a tube bundle mock-up for reliability studies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kupperman, D.S.; Bakhtiari, S.

1997-02-01

As part of an assessment of in-service inspection of steam generator tubes, the authors will assemble a steam generator mock-up for round robin studies and use as a test bed in evaluating emerging technologies. Progress is reported on the characterization of flaws that will be part of the mock-up. Eddy current and ultrasonic techniques are being evaluated as a means to characterize the flaws in the mock-up tubes before final assembly. Twenty Inconel 600 tubes with laboratory-grown cracks, typical of those to be used in the mock-up, were provided by Pacific Northwest National Laboratory for laboratory testing. After the tubesmore » were inspected with eddy current and ultrasonic techniques, they were destructively analyzed to establish the actual depths, lengths, and profiles of the cracks. The analysis of the results will allow the best techniques to be used for characterizing the flaws in the mock-up tubes.« less

SP2 Deployment at Boston College—Aerodyne-Led Coated Black Carbon Study (BC4) Final Campaign Summary

DOE Office of Scientific and Technical Information (OSTI.GOV)

Onasch, T. B.; Sedlacek, A. J.

The main objective of the Boston College-Aerodyne led laboratory study (BC4) was to measure the optical properties of black carbon (BC) particles from a diffusion flame directly and after being coated with secondary organic and inorganic material and to achieve optical closure with model predictions. The measurements of single particle BC mass and population mixing states provided by a single particle soot photometer (SP2) was central to achieving the laboratory-based study’s objective. Specifically, the DOE ARM SP2 instrument participated in the BC4 project to address the following scientific questions: 1. What is the mass-specific absorption coefficient as a function ofmore » secondary organic and inorganic material coatings? 2. What is the spread in the population mixing states within our carefully generated laboratory particles? 3. How does the SP2 instrument respond to well-characterized, internally mixed BC-containing particles?« less

Cassini Post End of Mission News Conference

NASA Image and Video Library

2017-09-15

On Sept. 15, NASA held a news conference from the agency’s Jet Propulsion Laboratory, in Pasadena, California, following the final mission activities of the agency’s Cassini mission to Saturn. Cassini, which arrived in orbit around Saturn in 2004 on a mission to study the giant planet, its rings, moons and magnetosphere, concluded its remarkable mission with an intentional plunge into Saturn's atmosphere..

Far infrared filters for a rocket-borne radiometer.

PubMed

Romero, H V; Gursky, J; Blair, A G

1972-04-01

Low pass far infrared radiation filters with cutoff frequencies in the spectral region of 10-25 cm(-1) were required for a rocket-borne radiometer experiment. The paper describes the theory, fabrication, and laboratory transmission measurements of prototype grid filters investigated in a study prior to the construction of flight filters. Characteristics of the final flight filters are also presented.

Longitudinal Associations between the Quality of Mother-Infant Interactions and Brain Development across Infancy

ERIC Educational Resources Information Center

Bernier, Annie; Calkins, Susan D.; Bell, Martha Ann

2016-01-01

The aim of this study was to investigate if normative variations in parenting relate to brain development among typically developing children. A sample of 352 mother-infant dyads came to the laboratory when infants were 5, 10, and 24 months of age (final N = 215). At each visit, child resting electroencephalography (EEG) was recorded.…

Algorithms and Architectures for Elastic-Wave Inversion Final Report CRADA No. TC02144.0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Larsen, S.; Lindtjorn, O.

2017-08-15

This was a collaborative effort between Lawrence Livermore National Security, LLC as manager and operator of Lawrence Livermore National Laboratory (LLNL) and Schlumberger Technology Corporation (STC), to perform a computational feasibility study that investigates hardware platforms and software algorithms applicable to STC for Reverse Time Migration (RTM) / Reverse Time Inversion (RTI) of 3-D seismic data.

Classroom Assessment for Student Learning: Impact on Elementary School Mathematics in the Central Region. Final Report. NCEE 2011-4005

ERIC Educational Resources Information Center

Randel, Bruce; Beesley, Andrea D.; Apthorp, Helen; Clark, Tedra F.; Wang, Xin; Cicchinelli, Louis F.; Williams, Jean M.

2011-01-01

This study was conducted by the Central Region Educational Laboratory (REL Central) administered by Mid-continent Research for Education and Learning to provide educators and policymakers with rigorous evidence about the potential of Classroom Assessment for Student Learning (CASL) to improve student achievement. CASL is a widely used professional…

SUSTAINABLE ALLOY DESIGN: SEARCHING FOR RARE EARTH ELEMENT ALTERNATIVES THROUGH CRYSTAL ENGINEERING

DTIC Science & Technology

2016-02-26

Property Maps to Guide Materials Design via Statistical Learning Summer Research Group Meeting – Materials by Design Los Alamos National Laboratory, July...Informatics, Rational design , Quantitative correlative spectroscopy and imaging, DFT, In situ high pressure mechanical property measurements, Superalloy...final, technical, interim, memorandum, master’s thesis, progress, quarterly, research , special, group study, etc. 3. DATES COVERED. Indicate the

Live load distribution on longitudinal glued-laminated timber deck bridges : final report : conclusions and recommendations

Treesearch

Fouad Fanous; Jeremy May; Terry Wipf; Michael Ritter

2010-01-01

Over the past few years the United States Department of Agriculture (USDA), Forest Products Laboratory (FPL), and the Federal Highway Administration (FHWA) have supported several research programs. This paper is a result of a study sponsored by FPL, with the objective of determining how truckloads are distributed to the deck panels of a longitudinal glued-laminated...

Brain Implants for Prediction and Mitigation of Epileptic Seizures - Final CRADA Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gopalsami, Nachappa

2016-09-29

This is a CRADA final report on C0100901 between Argonne National Laboratory and Flint Hills Scientific, LLC of Lawrence, Kansas. Two brain implantable probes, a surface acoustic wave probe and a miniature cooling probe, were designed, built, and tested with excellent results.

Comparison of a 50 mL pycnometer and a 500 mL flask, EURAMET.M.FF.S8 (EURAMET 1297)

NASA Astrophysics Data System (ADS)

Mićić, Ljiljana; Batista, Elsa

2018-01-01

The purpose of this comparison was to compare the results of the participating laboratories in the calibration of 50 mL pycnometer and 500 mL volumetric flask using the gravimetric method. Laboratories were asked to determined the 'contained' volume of the 50 mL pycnometer and of the 500 mL flask at a reference temperature of 20 °C. The gravimetric method was used for both instruments by all laboratories. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Characteristics of hardron-nucleus interactions at 100 GeV/c

NASA Astrophysics Data System (ADS)

Toothacker, W. S.; Whitmore, J.; Elcombe, P. A.; Hill, J. C.; Neale, W. W.; Kowald, W.; Walker, W. D.; Lucas, P.; Voyvodic, L.; Ammar, R.; Coppage, D.; Davis, R.; Gress, J.; Kanekal, S.; Kwak, N.; Bishop, J. M.; Biswas, N. N.; Cason, N. M.; Kenney, V. P.; Mattingly, M. C. K.; Ruchti, R. C.; Shepard, W. D.; Ting, S. J. Y.

1988-11-01

We report on 100 GeV/c interactions of p and p¯ with Ag and Au targets. This is a subset of the data from Fermilab experiment E597 and was performed with the 30-inch bubble chamber and Downstream Particle Identifier. Final state protons with laboratory momentum less than 1.4 GeV/c have been identified by their ionization in the bubble chamber. Final state protons/antiprotons with laboratory momentum greater than 10 GeV/c have been identified using CRISIS, an ionization sampling drift chamber. The cross section and mean transverse momentum squared of the leading baryon from the reactions p+(Ag,Au)→p+X and p¯+(Ag,Au)→p¯+X are presented as a function of the rapidity loss of the leading baryon. The laboratory rapidity and transverse momentum squared of the associated pions are also presented.

KEY COMPARISON: Final report of International Comparison EUROMET.QM-K1c: Comparison of measurements of nitrogen monoxide in nitrogen

NASA Astrophysics Data System (ADS)

van der Veen, A. M. H.; Nieuwenkamp, G.; Oudwater, R.; Wessel, R. M.; Novak, J.; Perrochet, J.-F.; Ackermann, A.; Rakowska, A.; Cortez, L.; Dias, F.; Konopelko, L.; Kustikov, Y.; Sutour, C.; Masé, T.; Milton, M. J. T.; Uprichard, I. J.; Woods, P. T.; Walden, J.; Lopez Esteban, M. T.

2005-01-01

Following-up the key comparison CCQM-K1c, EUROMET organized a regional key comparison involving ten laboratories. The objectives of this EUROMET key comparison were essentially the same as for the CCQM-K1c comparison: to compare the measurement capabilities of national metrological institutes (NMIs) in measuring amount of substance fractions of nitrogen monoxide in nitrogen. The nominal amount of substance fraction of the standards used for the comparison was 100 µmol/mol. The pilot laboratory in this key comparison also piloted the CCQM key comparison and has long-term experience in the behaviour of these mixtures and the technical challenges in preparing batches of very similar mixtures. Most participants used chemiluminescence as the measurement method; two participants used UV techniques and one ND-IR. The degrees of equivalence between this comparison and CCQM-K1c were calculated; four laboratories participated in both key comparisons, thus providing sufficient data for demonstrating the comparability. Main text. To reach the main text of this paper, click on Final Report. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the Mutual Recognition Arrangement (MRA).

Medicare program; payment policies under the physician fee schedule, five-year review of work relative value units, clinical laboratory fee schedule: signature on requisition, and other revisions to part B for CY 2012. Final rule with comment period.

PubMed

2011-11-28

This final rule with comment period addresses changes to the physician fee schedule and other Medicare Part B payment policies to ensure that our payment systems are updated to reflect changes in medical practice and the relative value of services. It also addresses, implements or discusses certain statutory provisions including provisions of the Patient Protection and Affordable Care Act, as amended by the Health Care and Education Reconciliation Act of 2010 (collectively known as the Affordable Care Act) and the Medicare Improvements for Patients and Providers Act (MIPPA) of 2008. In addition, this final rule with comment period discusses payments for Part B drugs; Clinical Laboratory Fee Schedule: Signature on Requisition; Physician Quality Reporting System; the Electronic Prescribing (eRx) Incentive Program; the Physician Resource-Use Feedback Program and the value modifier; productivity adjustment for ambulatory surgical center payment system and the ambulance, clinical laboratory, and durable medical equipment prosthetics orthotics and supplies (DMEPOS) fee schedules; and other Part B related issues.

Dynamics of yield-stress droplets: Morphology of impact craters

NASA Astrophysics Data System (ADS)

Neufeld, Jerome; Sohr, David; Ferrari, Leo; Dalziel, Stuart

2017-11-01

Yield strength can play an important role for the dynamics of droplets impacting on surfaces, whether at the industrial or planetary scale, and can capture a zoo of impact crater morphologies, from simple parabolic craters, to more complex forms with forms with, for example, multiple rings, central peaks. Here we show that the morphology of planetary impact craters can be reproduced in the laboratory using carbopol, a transparent yield-stress fluid, as both impactor and bulk fluid. Using high-speed video photography, we characterise the universal, transient initial excavation stage of impact and show the dependence of the subsequent relaxation to final crater morphology on impactor size, impact speed and yield stress. To further interrogate our laboratory impacts, we dye our impactor to map its final distribution and use particle tracking to determine the flow fields during impact and the maximal extent of the yield surface. We characterise the flow-fields induced during impact, and the maximal extent of the yield surface, by tracking particles within the bulk fluid and map the distribution of impactor and bulk by tracing the final distribution of dyed impactor. The results of laboratory impact droplets are used to infer the properties of planetary impactors, and aid in inter.

Environmental Technology (Laboratory Analysis and Environmental Sampling) Curriculum Development Project. Final Report.

ERIC Educational Resources Information Center

Hinojosa, Oscar V.; Guillen, Alfonso

A project assessed the need and developed a curriculum for environmental technology (laboratory analysis and environmental sampling) in the emerging high technology centered around environmental safety and health in Texas. Initial data were collected through interviews by telephone and in person and through onsite visits. Additional data was…

Promoting Probabilistic Programming System (PPS) Development in Probabilistic Programming for Advancing Machine Learning (PPAML)

DTIC Science & Technology

2018-03-01

MARCH 2018 FINAL TECHNICAL REPORT APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED STINFO COPY AIR FORCE RESEARCH LABORATORY INFORMATION...SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) Air Force Research Laboratory/RITA DARPA 525 Brooks Road 675 North Randolph Street Rome...1 3.0 METHODS , ASSUMPTIONS, AND PROCEDURES

Clinical Laboratory Sciences Discipline Advisory Group Final Report. Kentucky Allied Health Project.

ERIC Educational Resources Information Center

Kentucky Council on Public Higher Education, Frankfort.

Education in the clinical laboratory sciences in Kentucky and articulation within the field are examined, based on the Kentucky Allied Health Project (KAHP), which designed an articulated statewide system to promote entry and exit of personnel at a variety of educational levels. The KAHP model promotes articulation in learning, planning, and…

Learning in the Laboratory: How Group Assignments Affect Motivation and Performance

ERIC Educational Resources Information Center

Belanger, John R.

2016-01-01

Team projects can optimize educational resources in a laboratory, but also create the potential for social loafing. Allowing students to choose their own groups could increase their motivation to learn and improve academic performance. To test this hypothesis, final grades and feedback from students were compared for the same course in two…

Developing School Laboratories To Promote the Establishment of Individual Experience Programs. Final Report.

ERIC Educational Resources Information Center

Valley Springs School District 2, AR.

A project was conducted to promote and develop individual Supervised Agricultural Experience (SAE) programs in Arkansas through the development of laboratories. It was felt that strong SAE programs enhance the instructional portion of agriculture education, serve as a motivational tool, and improve the relations between the local school and…

Computer Exercises in Systems and Fields Experiments

ERIC Educational Resources Information Center

Bacon, C. M.; McDougal, J. R.

1971-01-01

Laboratory activities give students an opportunity to interact with computers in modes ranging from remote terminal use in laboratory experimentation to the direct hands-on use of a small digital computer with disk memory and on-line plotter, and finally to the use of a large computer under closed-shop operation. (Author/TS)

Synthesis of a Fluorescent Acridone Using a Grignard Addition, Oxidation, and Nucleophilic Aromatic Substitution Reaction Sequence

ERIC Educational Resources Information Center

Goodrich, Samuel; Patel, Miloni; Woydziak, Zachary R.

2015-01-01

A three-pot synthesis oriented for an undergraduate organic chemistry laboratory was developed to construct a fluorescent acridone molecule. This laboratory experiment utilizes Grignard addition to an aldehyde, alcohol oxidation, and iterative nucleophilic aromatic substitution steps to produce the final product. Each of the intermediates and the…

Hydraulic manipulator design, analysis, and control at Oak Ridge National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kress, R.L.; Jansen, J.F.; Love, L.J.

1996-09-01

To meet the increased payload capacities demanded by present-day tasks, manipulator designers have turned to hydraulics as a means of actuation. Hydraulics have always been the actuator of choice when designing heavy-life construction and mining equipment such as bulldozers, backhoes, and tunneling devices. In order to successfully design, build, and deploy a new hydraulic manipulator (or subsystem) sophisticated modeling, analysis, and control experiments are usually needed. To support the development and deployment of new hydraulic manipulators Oak Ridge National Laboratory (ORNL) has outfitted a significant experimental laboratory and has developed the software capability for research into hydraulic manipulators, hydraulic actuators,more » hydraulic systems, modeling of hydraulic systems, and hydraulic controls. The hydraulics laboratory at ORNL has three different manipulators. First is a 6-Degree-of-Freedom (6-DoF), multi-planer, teleoperated, flexible controls test bed used for the development of waste tank clean-up manipulator controls, thermal studies, system characterization, and manipulator tracking. Finally, is a human amplifier test bed used for the development of an entire new class of teleoperated systems. To compliment the hardware in the hydraulics laboratory, ORNL has developed a hydraulics simulation capability including a custom package to model the hydraulic systems and manipulators for performance studies and control development. This paper outlines the history of hydraulic manipulator developments at ORNL, describes the hydraulics laboratory, discusses the use of the equipment within the laboratory, and presents some of the initial results from experiments and modeling associated with these hydraulic manipulators. Included are some of the results from the development of the human amplifier/de-amplifier concepts, the characterization of the thermal sensitivity of hydraulic systems, and end-point tracking accuracy studies. Experimental and analytical results are included.« less

Validity of a heart rate monitor during work in the laboratory and on the Space Shuttle

NASA Technical Reports Server (NTRS)

Moore, A. D. Jr; Lee, S. M.; Greenisen, M. C.; Bishop, P.

1997-01-01

Accurate heart rate measurement during work is required for many industrial hygiene and ergonomics situations. The purpose of this investigation was to determine the validity of heart rate measurements obtained by a simple, lightweight, commercially available wrist-worn heart rate monitor (HRM) during work (cycle exercise) sessions conducted in the laboratory and also during the particularly challenging work environment of space flight. Three different comparisons were made. The first compared HRM data to simultaneous electrocardiogram (ECG) recordings of varying heart rates that were generated by an ECG simulator. The second compared HRM data to ECG recordings collected during work sessions of 14 subjects in the laboratory. Finally, ECG downlink and HRM data were compared in four astronauts who performed cycle exercise during space flight. The data were analyzed using regression techniques. The results were that the HRM recorded virtually identical heart rates compared with ECG recordings for the data set generated by an ECG simulator. The regression equation for the relationship between ECG versus HRM heart rate data during work in the laboratory was: ECG HR = 0.99 x (HRM) + 0.82 (r2 = 0.99). Finally, the agreement between ECG downlink data and HRM data during space flight was also very high, with the regression equation being: Downlink ECG HR = 1.05 x (HRM) -5.71 (r2 = 0.99). The results of this study indicate that the HRM provides accurate data and may be used to reliably obtain valid data regarding heart rate responses during work.

Automated reporting of pharmacokinetic study results: gaining efficiency downstream from the laboratory.

PubMed

Schaefer, Peter

2011-07-01

The purpose of bioanalysis in the pharmaceutical industry is to provide 'raw' data about the concentration of a drug candidate and its metabolites as input for studies of drug properties such as pharmacokinetic (PK), toxicokinetic, bioavailability/bioequivalence and other studies. Building a seamless workflow from the laboratory to final reports is an ongoing challenge for IT groups and users alike. In such a workflow, PK automation can provide companies with the means to vastly increase the productivity of their scientific staff while improving the quality and consistency of their reports on PK analyses. This report presents the concept and benefits of PK automation and discuss which features of an automated reporting workflow should be translated into software requirements that pharmaceutical companies can use to select or build an efficient and effective PK automation solution that best meets their needs.

Test-Enhanced Learning: The Potential for Testing to Promote Greater Learning in Undergraduate Science Courses

PubMed Central

Brame, Cynthia J.; Biel, Rachel

2015-01-01

Testing within the science classroom is commonly used for both formative and summative assessment purposes to let the student and the instructor gauge progress toward learning goals. Research within cognitive science suggests, however, that testing can also be a learning event. We present summaries of studies that suggest that repeated retrieval can enhance long-term learning in a laboratory setting; various testing formats can promote learning; feedback enhances the benefits of testing; testing can potentiate further study; and benefits of testing are not limited to rote memory. Most of these studies were performed in a laboratory environment, so we also present summaries of experiments suggesting that the benefits of testing can extend to the classroom. Finally, we suggest opportunities that these observations raise for the classroom and for further research. PMID:25999314

Establishment of National Laboratory Standards in Public and Private Hospital Laboratories

PubMed Central

ANJARANI, Soghra; SAFADEL, Nooshafarin; DAHIM, Parisa; AMINI, Rana; MAHDAVI, Saeed; MIRAB SAMIEE, Siamak

2013-01-01

In September 2007 national standard manual was finalized and officially announced as the minimal quality requirements for all medical laboratories in the country. Apart from auditing laboratories, Reference Health Laboratory has performed benchmarking auditing of medical laboratory network (surveys) in provinces. 12th benchmarks performed in Tehran and Alborz provinces, Iran in 2010 in three stages. We tried to compare different processes, their quality and accordance with national standard measures between public and private hospital laboratories. The assessment tool was a standardized checklist consists of 164 questions. Analyzing process show although in most cases implementing the standard requirements are more prominent in private laboratories, there is still a long way to complete fulfillment of requirements, and it takes a lot of effort. Differences between laboratories in public and private sectors especially in laboratory personnel and management process are significant. Probably lack of motivation, plays a key role in obtaining less desirable results in laboratories in public sectors. PMID:23514840

Characterizing High School Students' Written Explanations in Biology Laboratories

NASA Astrophysics Data System (ADS)

Peker, Deniz; Wallace, Carolyn S.

2011-03-01

The purpose of this qualitative interpretive research study was to examine high school students' written scientific explanations during biology laboratory investigations. Specifically, we characterized the types of epistemologies and forms of reasoning involved in students' scientific explanations and students' perceptions of scientific explanations. Sixteen students from a rural high school in the Southeastern United States were the participants of this research study. The data consisted of students' laboratory reports and individual interviews. The results indicated that students' explanations were primarily based on first-hand knowledge gained in the science laboratories and mostly representing procedural recounts. Most students did not give explanations based on a theory or a principle and did not use deductive reasoning in their explanations. The students had difficulties explaining phenomena that involved intricate cause-effect relationships. Students perceived scientific explanation as the final step of a scientific inquiry and as an account of what happened in the inquiry process, and held a constructivist-empiricist view of scientific explanations. Our results imply the need for more explicit guidance to help students construct better scientific explanations and explicit teaching of the explanatory genre with particular focus on theoretical and causal explanations.

Final report on the supplementary comparison, EURAMET.M.P-S7 (EURAMET project 1040) in the pressure range from 1.10-4 Pa to 0.9 Pa

NASA Astrophysics Data System (ADS)

Wüthrich, C.; Alisic, S.; Bergoglio, M.; Saxholm, S.; Lefkopoulos, A.; Pražák, D.; Setina, J.

2016-01-01

Many laboratories within EURAMET started a calibration service in medium and high vacuum recently and did not have the opportunity to take part to a comparison before. In order to assess the uncertainty budget and the quality of the measurement of these laboratories, an intercomparison, EURAMET 1040 registered as EURAMET.M.P-S7, from 0.1 mPa to 0.9 Pa has been organised. The participants are the CMI (Czech republic), EIM (Greece), IMT (Slovenia), INRIM (Italy), IMBIH (Bosnia Herzegovinia) and MIKES (Finland) while METAS (Switzerland) is pilot laboratory. Three laboratories (INRIM, CMI and METAS) involved in this work have a primary definition of the pressure. Two spinning rotor gauges and a control electronic are used as transfer standard. The circulation of the transfer standard is organised as a succession of loops with a measurement by the pilot between each participant. A reference value has been determined based on a weighted mean of the results of the primary laboratories. All the participants have demonstrated their equivalence in the definition of the pressure. This comparison has been used as pilot comparison for the CCM.P-K14 project which covers the same scope with similar transfer standards. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Incorporating modeling and simulations in undergraduate biophysical chemistry course to promote understanding of structure-dynamics-function relationships in proteins.

PubMed

Hati, Sanchita; Bhattacharyya, Sudeep

2016-01-01

A project-based biophysical chemistry laboratory course, which is offered to the biochemistry and molecular biology majors in their senior year, is described. In this course, the classroom study of the structure-function of biomolecules is integrated with the discovery-guided laboratory study of these molecules using computer modeling and simulations. In particular, modern computational tools are employed to elucidate the relationship between structure, dynamics, and function in proteins. Computer-based laboratory protocols that we introduced in three modules allow students to visualize the secondary, super-secondary, and tertiary structures of proteins, analyze non-covalent interactions in protein-ligand complexes, develop three-dimensional structural models (homology model) for new protein sequences and evaluate their structural qualities, and study proteins' intrinsic dynamics to understand their functions. In the fourth module, students are assigned to an authentic research problem, where they apply their laboratory skills (acquired in modules 1-3) to answer conceptual biophysical questions. Through this process, students gain in-depth understanding of protein dynamics-the missing link between structure and function. Additionally, the requirement of term papers sharpens students' writing and communication skills. Finally, these projects result in new findings that are communicated in peer-reviewed journals. © 2016 The International Union of Biochemistry and Molecular Biology.

Using ultrasound to teach medical students cardiac physiology.

PubMed

Bell, Floyd E; Wilson, L Britt; Hoppmann, Richard A

2015-12-01

Ultrasound is being incorporated more into undergraduate medical education. Studies have shown that medical students have positive perceptions about the value of ultrasound in teaching courses like anatomy and physiology. The purpose of the present study was to provide objective evidence of whether ultrasound helps students learn cardiac physiology. In this study, 20 medical students took a pretest to assess their background knowledge of cardiac physiology. Next, they acquired ultrasound video loops of the heart. Faculty members taught them nonelectrical aspects of cardiac physiology using those loops. Finally, students took a posttest to evaluate for improvements in their knowledge. Students also completed an anonymous questionnaire about their experience. The mean pretest score was 4.8 of 9 (53.3%). The mean posttest score was 7.35 of 9 (81.7%). The mean difference was significant at P < 0.0001. Student feedback was very positive about the ultrasound laboratory. Ninety-five percent of the students agreed or strongly agreed that the ultrasound laboratory was a valuable teaching tool and that it improved their understanding of cardiac physiology. All students agreed or strongly agreed the laboratory was helpful from a visual learning standpoint. A hands-on ultrasound laboratory can indeed help medical students learn the nonelectrical components of cardiac physiology. Copyright © 2015 The American Physiological Society.

Laboratory testing in hyperthyroidism.

PubMed

Grebe, Stefan K G; Kahaly, George J

2012-09-01

The clinical diagnosis of hypo- or hyperthyroidism is difficult (full text available online: http://education.amjmed.com/pp1/272). Clinical symptoms and signs are often non-specific, and there is incomplete correlation between structural and functional thyroid gland changes. Laboratory testing is therefore indispensible in establishing the diagnosis of thyrotoxicosis. Similar considerations apply to treatment monitoring. Laboratory testing also plays a crucial role in establishing the most likely cause for a patient's hyperthyroidism. Finally, during pregnancy, when isotopic scanning is relatively contraindicated and ultrasound is more difficult to interpret, laboratory testing becomes even more important. Copyright © 2012. Published by Elsevier Inc.

Experiment plans to study preignition processes of a pool fire in low gravity. M.S. Thesis - 1988 Final Report

NASA Technical Reports Server (NTRS)

Schiller, David N.

1989-01-01

Science requirements are specified to guide experimental studies of transient heat transfer and fluid flow in an enclosure containing a two-layer gas-and-liquid system heated unevenly from above. Specifications are provided for experiments in three separate settings: (1) a normal gravity laboratory, (2) the NASA-LeRC Drop towers, and (3) a space-based laboratory (e.g., Shuttle, Space Station). A rationale is developed for both minimum and desired requirement levels. The principal objective of the experimental effort is to validate a computational model of the enclosed liquid fuel pool during the preignition phase and to determine via measurement the role of gravity on the behavior of the system. Preliminary results of single-phase normal gravity experiments and simulations are also presented.

Creating and Disseminating Knowledge for Educational Reform: Policy Management of the National Institute of Education's Regional Educational Laboratories and National Research and Development Centers. A Report to the National Council on Educational Research. [Executive Summary and Final Report].

ERIC Educational Resources Information Center

Center for Leadership Development, Los Angeles, CA.

Drawing on interviews, documents, and eight studies, this policy research study offers information and recommendations in order to fulfill the responsibility of the National Council on Educational Research to establish general policies for, and review the conduct of, the National Institute of Education (NIE). Questions guiding this study are: the…

Final report of the regional key comparison EURAMET.M.G-K1: European Comparison of Absolute Gravimeters ECAG-2011

NASA Astrophysics Data System (ADS)

Francis, Olivier; Klein, Gilbert; Baumann, Henri; Dando, Nicolas; Tracey, Ray; Ullrich, Christian; Castelein, Stefaan; Hua, Hu; Kang, Wu; Chongyang, Shen; Songbo, Xuan; Hongbo, Tan; Zhengyuan, Li; Pálinkás, Vojtech; Kostelecký, Jakub; Mäkinen, Jaakko; Näränen, Jyri; Merlet, Sébastien; Farah, Tristan; Guerlin, Christine; Pereira Dos Santos, Franck; Le Moigne, Nicolas; Champollion, Cédric; Deville, Sabrina; Timmen, Ludger; Falk, Reinhard; Wilmes, Herbert; Iacovone, Domenico; Baccaro, Francesco; Germak, Alessandro; Biolcati, Emanuele; Krynski, Jan; Sekowski, Marcin; Olszak, Tomasz; Pachuta, Andrzej; Agren, Jonas; Engfeldt, Andreas; Reudink, René; Inacio, Pedro; McLaughlin, Daniel; Shannon, Geoff; Eckl, Marc; Wilkins, Tim; van Westrum, Derek; Billson, Ryan

2012-01-01

During November 2011 a EURAMET key comparison of absolute gravimeters was organized in the Underground Laboratory for Geodynamics in Walferdange, Luxemburg. The comparison assembled 22 participants coming from 16 countries and four different continents. The comparison was divided into two parts: a key comparison that included six National Metrology Institutes or Designated Institutes, and a pilot study including all participants. The global result given by the pilot study confirms that all instruments are absolutely coherent with each other. The results obtained in the key comparison confirm a good agreement between the NMI instruments. Finally, a link to ICAG-2009 shows also that the NMI gravimeters are stable in time. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Final Report National Laboratory Professional Development Workshop for Underrepresented Participants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Taylor, Valerie

The 2013 CMD-IT National Laboratories Professional Development Workshop for Underrepresented Participants (CMD-IT NLPDev 2013) was held at the Oak Ridge National Laboratory campus in Oak Ridge, TN. from June 13 - 14, 2013. Sponsored by the Department of Energy (DOE) Advanced Scientific Computing Research Program, the primary goal of these workshops is to provide information about career opportunities in computational science at the various national laboratories and to mentor the underrepresented participants through community building and expert presentations focused on career success. This second annual workshop offered sessions to facilitate career advancement and, in particular, the strategies and resources neededmore » to be successful at the national laboratories.« less

PLACE: an open-source python package for laboratory automation, control, and experimentation.

PubMed

Johnson, Jami L; Tom Wörden, Henrik; van Wijk, Kasper

2015-02-01

In modern laboratories, software can drive the full experimental process from data acquisition to storage, processing, and analysis. The automation of laboratory data acquisition is an important consideration for every laboratory. When implementing a laboratory automation scheme, important parameters include its reliability, time to implement, adaptability, and compatibility with software used at other stages of experimentation. In this article, we present an open-source, flexible, and extensible Python package for Laboratory Automation, Control, and Experimentation (PLACE). The package uses modular organization and clear design principles; therefore, it can be easily customized or expanded to meet the needs of diverse laboratories. We discuss the organization of PLACE, data-handling considerations, and then present an example using PLACE for laser-ultrasound experiments. Finally, we demonstrate the seamless transition to post-processing and analysis with Python through the development of an analysis module for data produced by PLACE automation. © 2014 Society for Laboratory Automation and Screening.

Competitive bidding for Medicare Part B clinical laboratory services.

PubMed

Kautter, John; Pope, Gregory C

2014-06-01

The traditional Medicare fee-for-service program may be able to purchase clinical laboratory test services at a lower cost through competitive bidding. Demonstrations of competitive bidding for clinical laboratory tests have been twice mandated or authorized by Congress but never implemented. This article provides a summary and review of the final design of the laboratory competitive bidding demonstration mandated by the Medicare Modernization Act of 2003. The design was analogous to a sealed bid (first price), clearing price auction. Design elements presented include covered laboratory tests and beneficiaries, laboratory bidding and payment status under the demonstration, composite bids, determining bidding winners and the demonstration fee schedule, and quality under the demonstration. Expanded use of competitive bidding in Medicare, including specifically for clinical laboratory tests, has been recommended in some proposals for Medicare reform. The presented design may be a useful point of departure if Medicare clinical laboratory competitive bidding is revived in the future.

Students' motivation toward laboratory work in physiology teaching.

PubMed

Dohn, Niels Bonderup; Fago, Angela; Overgaard, Johannes; Madsen, Peter Teglberg; Malte, Hans

2016-09-01

The laboratory has been given a central role in physiology education, and teachers report that it is motivating for students to undertake experimental work on live animals or measuring physiological responses on the students themselves. Since motivation is a critical variable for academic learning and achievement, then we must concern ourselves with questions that examine how students engage in laboratory work and persist at such activities. The purpose of the present study was to investigate how laboratory work influences student motivation in physiology. We administered the Lab Motivation Scale to assess our students' levels of interest, willingness to engage (effort), and confidence in understanding (self-efficacy). We also asked students about the role of laboratory work for their own learning and their experience in the physiology laboratory. Our results documented high levels of interest, effort, and self-efficacy among the students. Correlation analyses were performed on the three motivation scales and exam results, yet a significant correlation was only found between self-efficacy in laboratory work and academic performance at the final exam. However, almost all students reported that laboratory work was very important for learning difficult concepts and physiological processes (e.g., action potential), as the hands-on experiences gave a more concrete idea of the learning content and made the content easier to remember. These results have implications for classroom practice as biology students find laboratory exercises highly motivating, despite their different personal interests and subject preferences. This highlights the importance of not replacing laboratory work by other nonpractical approaches, for example, video demonstrations or computer simulations. Copyright © 2016 The American Physiological Society.

Determination of Soil Moisture Content using Laboratory Experimental and Field Electrical Resistivity Values

NASA Astrophysics Data System (ADS)

Hazreek, Z. A. M.; Rosli, S.; Fauziah, A.; Wijeyesekera, D. C.; Ashraf, M. I. M.; Faizal, T. B. M.; Kamarudin, A. F.; Rais, Y.; Dan, M. F. Md; Azhar, A. T. S.; Hafiz, Z. M.

2018-04-01

The efficiency of civil engineering structure require comprehensive geotechnical data obtained from site investigation. In the past, conventional site investigation was heavily related to drilling techniques thus suffer from several limitations such as time consuming, expensive and limited data collection. Consequently, this study presents determination of soil moisture content using laboratory experimental and field electrical resistivity values (ERV). Field and laboratory electrical resistivity (ER) test were performed using ABEM SAS4000 and Nilsson400 soil resistance meter. Soil sample used for resistivity test was tested for characterization test specifically on particle size distribution and moisture content test according to BS1377 (1990). Field ER data was processed using RES2DINV software while laboratory ER data was analyzed using SPSS and Excel software. Correlation of ERV and moisture content shows some medium relationship due to its r = 0.506. Moreover, coefficient of determination, R2 analyzed has demonstrate that the statistical correlation obtain was very good due to its R2 value of 0.9382. In order to determine soil moisture content based on statistical correlation (w = 110.68ρ-0.347), correction factor, C was established through laboratory and field ERV given as 19.27. Finally, this study has shown that soil basic geotechnical properties with particular reference to water content was applicably determined using integration of laboratory and field ERV data analysis thus able to compliment conventional approach due to its economic, fast and wider data coverage.

Final report on APMP.M.H-S3: Comparison on hardness measurement Rockwell scale A and B

NASA Astrophysics Data System (ADS)

Sanponpute, Tassanai; Meesaplak, Apichaya; Menelao, Febo; Chan, T. K.; Bahng, Gun-Woong; Titus, S. S. K.; Jain, S. K.

2012-01-01

The APMP.M.H-S3 Rockwell hardness intercomparison was initiated by NIMT, Thailand and the required protocol was prepared by NIMT and checked by Dr John Man, MNIA, Australia, in 2009. PTB, Germany, Standards and Calibration Laboratory (SCL), Hong Kong, National Physical Laboratory (NPLI), India, and Korea Research Institute of Standards and Science (KRISS), Korea, participated in this comparison. This comparison exercise was focused on the measurement range of 25 to 100 HRBW scale and 35 to 85 HRA scale. The round robin test was done during the period from April 2010 to October 2010. The participating laboratories have demonstrated the capability of the machine and the operating conditions according to ISO 6508 Part 3 to perform the measurements. However, SCL, Hong Kong, could demonstrate their capability to perform the measurements only according to ISO 6508 Part 2. The CMCs declared by the different laboratories lie in the range of 0.30 HRA to 0.40 HRA and 0.40 HRBW to 0.75 HRBW. The CMC declared by SCL for the Rockwell B scale is 1.5 HRBW for the reason described above. It is observed from the results that the measurement uncertainty is estimated not less than the CMCs declared by the laboratories. From the measurement results provided by all the participating laboratories, the En ratio was determined to establish the degrees of equivalence. The En ratio was calculated by including as well as by excluding the results of the laboratory which has performed the test according to ISO 6508 Part 2 in order to make sure that it does not affect the overall results. It is noticed that the En ratio was still found to remain less than 1. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the APMP, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Characterization of nonplanar motion in MEMS involving scanning laser interferometry

NASA Astrophysics Data System (ADS)

Lawton, Russell A.; Abraham, Margaret H.; Lawrence, Eric

1999-08-01

A study to evaluate three processes used for the release of standard devices produced by MCNC using the MUMPS process was undertaken by Jet Propulsion Laboratory with the collaboration of The Aerospace Corporation, and Polytec PI. The processes used were developed at various laboratories and are commonly the final step in the production of micro- electro-mechanical systems prior to packaging. It is at this stage of the process when the devices become extremely delicate and are subject to yield losses due to handling errors or the phenomenon of stiction. The effects of post processing with HF on gain boundaries and subsequent thermal processing producing native oxide growth during packaging will require further investigation.

Electrocoagulation of wastewater from almond industry.

PubMed

Valero, David; Ortiz, Juan M; García, Vicente; Expósito, Eduardo; Montiel, Vicente; Aldaz, Antonio

2011-08-01

This work was carried out to study the treatment of almond industry wastewater by the electrocoagulation process. First of all, laboratory scale experiments were conducted in order to determine the effects of relevant wastewater characteristics such as conductivity and pH, as well as the process variables such as anode material, current density and operating time on the removal efficiencies of the total organic carbon (TOC) and the most representative analytical parameters. Next, the wastewater treatment process was scaled up to pre-industrial size using the best experimental conditions and parameters obtained at laboratory scale. Finally, economic parameters such as chemicals, energy consumption and sludge generation have been discussed. Copyright © 2011 Elsevier Ltd. All rights reserved.

Teaching laboratory neuroscience at bowdoin: the laboratory instructor perspective.

PubMed

Hauptman, Stephen; Curtis, Nancy

2009-01-01

Bowdoin College is a small liberal arts college that offers a comprehensive Neuroscience major. The laboratory experience is an integral part of the major, and many students progress through three stages. A core course offers a survey of concepts and techniques. Four upper-level courses function to give students more intensive laboratory research experience in neurophysiology, molecular neurobiology, social behavior, and learning and memory. Finally, many majors choose to work in the individual research labs of the Neuroscience faculty. We, as laboratory instructors, are vital to the process, and are actively involved in all aspects of the lab-based courses. We provide student instruction in state of the art techniques in neuroscience research. By sharing laboratory teaching responsibilities with course professors, we help to prepare students for careers in laboratory neuroscience and also support and facilitate faculty research programs.

Favouring more rigour when investigating human eating behaviour is like supporting motherhood and apple pie: A response to Robinson, Bevelander, Field, and Jones (2018).

PubMed

Hetherington, Marion M; Rolls, Barbara J

2018-05-11

In a 1987 paper, addressing questions about factors that influence the initiation, maintenance, and termination of food intake, we wrote, "development of systematic procedures to measure eating behaviour is essential if descriptive and inferential statistics are to be applied to answering such questions, giving them power and replicability" (Hetherington & Rolls, 1987 page 77). Therefore, as longstanding advocates of rigorous procedures in laboratory-based investigations of food intake, we welcome Robinson et al.'s (2018) clear recommendations for laboratory studies. However, this is akin to voting for "motherhood and apple pie", and few would argue against deployment of improved procedures for these studies. What then can we contribute to the debate in order to refine the recommendations made or add to them? Our most important message for researchers is that the central hypothesis or main research question will determine the most appropriate methods for any study. If a laboratory-based study is planned, then there are basic methodological questions that must be answered before proceeding to a final protocol. While such guidelines are needed to ensure basic methodological rigour, these should not be so prescriptive as to inhibit creativity. Here we provide several thoughts on how to advance studies of ingestive behaviour, including the need to apply appropriate controls, encouragement to move beyond convenience samples, and to remember the value of exploratory, observational, and naturalistic studies to complement laboratory-based studies. Copyright © 2018. Published by Elsevier Ltd.

Managing laboratory automation

PubMed Central

Saboe, Thomas J.

1995-01-01

This paper discusses the process of managing automated systems through their life cycles within the quality-control (QC) laboratory environment. The focus is on the process of directing and managing the evolving automation of a laboratory; system examples are given. The author shows how both task and data systems have evolved, and how they interrelate. A BIG picture, or continuum view, is presented and some of the reasons for success or failure of the various examples cited are explored. Finally, some comments on future automation need are discussed. PMID:18925018

Managing laboratory automation.

PubMed

Saboe, T J

1995-01-01

This paper discusses the process of managing automated systems through their life cycles within the quality-control (QC) laboratory environment. The focus is on the process of directing and managing the evolving automation of a laboratory; system examples are given. The author shows how both task and data systems have evolved, and how they interrelate. A BIG picture, or continuum view, is presented and some of the reasons for success or failure of the various examples cited are explored. Finally, some comments on future automation need are discussed.

Exploring the Content of Shared Mental Models in Project Teams

DTIC Science & Technology

2005-09-30

FINAL REPORT Grant Title: EXPLORING THE CONTENT OF SHARED MENTAL MODELS IN PROJECT TEAMS Office of Naval Research Award Number: N000140210535... Research Laboratory, Attn: code 5227, 4555 Overlook Ave., SW, Washington, DC •t• The University of Massachusetts Amherst is an Affirmative Action/Equal...satisfaction. 2.0 PROJECT SUMMARY No consensus among researchers studying shared cognition exists regarding the identification of what should be

Technical Feasibility Study of an Effective Low-Toxicity Obscurant Material

DTIC Science & Technology

2012-08-01

2. REPORT TYPE FINAL 3. DATES COVERED (From - To) 04/2011 – 07/2012 4 . TITLE AND SUBTITLE 5a. CONTRACT NUMBER W912HQ-11-C-0034 Technical...6 4 Work Package 3 – Laboratory-scale tests...chemistry to sea-salt aerosol. 4 The major component of sea-salt is sodium chloride. Sodium chloride can be very simply generated by the combustion

SELECTIVE DISSEMINATION OF INFORMATION (SDI). VOLUME II, IMPLEMENTATION MANUAL. FINAL REPORT. ARMY TECHNICAL LIBRARY IMPROVEMENT STUDIES (ATLIS), REPORT NO. 16.

ERIC Educational Resources Information Center

BIVONA, WILLIAM A.

A SET OF GUIDELINES FOR IMPLEMENTING AND OPERATING A REPLICA OF A PROTOTYPE SELECTIVE DISSEMINATION OF INFORMATION (SDI) SYSTEM TESTED AT U.S. ARMY NATICK LABORATORIES, AND REPORTED IN LI 000 273, IS GIVEN IN THIS MANUAL. INFORMATION IS SUPPLIED WHICH IS USEFUL IN THE INITIAL STAGES OF IMPLEMENTATION. THE APPLICATION OF SPECIFIC CRITERIA FOR…

Windshear detection radar signal processing studies

NASA Technical Reports Server (NTRS)

Baxa, Ernest G., Jr.

1993-01-01

This final report briefly summarizes research work at Clemson in the Radar Systems Laboratory under the NASA Langley Research Grant NAG-1-928 in support of the Antenna and Microwave Branch, Guidance and Control Division, program to develop airborne sensor technology for the detection of low altitude windshear. A bibliography of all publications generated by Clemson personnel is included. An appendix provides abstracts of all publications.

USAF Summer Research Program - 1994 Summer Faculty Research Program Final Reports, Volume 2A, Armstrong Laboratory.

DTIC Science & Technology

1994-12-01

meta-analytic approach . Journal of Applied Psychology , 76, 432-446. 6-14 Raju, N.S., & Dowhower, D.P. (1991). The effect of second-order sampling on the... Psychology . HARPER, G., & KEMBER, D. (1989). Interpretation of factor analysis from the approaches to studying inventory. British Journal of Educational...Contemporary Educational Psychology , 12, 381-385. TRIGWELL, K., & PROSSER, M. (1991). Relating approaches to study and quality of learning outcomes at

PSU/WES Interlaboratory Comparative Methodology Study of an Experimental Cementitious Repository Seal Material. Report 2. Final Results.

DTIC Science & Technology

1982-03-01

meter 25 11.0 Microstructure by SEM 11.1 Introduction In order to correlate observed physical and mechanical properties in cured grout samples, a...studied at the two laboratories has proper physical properties , phase composi- tions, and microstructures for the materials used and ages covered...Scanning Electron Microscope Resolution Test Specimen ( Al -W) D. B. Ballard Research Material 100 SEM Resolution Test Specimen (AI-W)., is an alloy of

Preferred temperatures of juvenile lake whitefish

USGS Publications Warehouse

Edsall, Thomas A.

1999-01-01

Lake whitefish (Coregonus clupeaformis) supported valuable commercial fisheries in all of the Great Lakes until the 1950s to 1960s when their populations collapsed due to overfishing, pollution, and predation by the exotic sea lamprey (Petromyzon marinus). Reduction of these population stresses has permitted significant recovery of the lake whitefish in the upper three Great Lakes since the 1980s, and limited but encouraging recovery is now apparent in Lakes Erie and Ontario. In the present study the thermal preferences of age-0 and age-1 lake whitefish were measured in the laboratory to provide a basis for determining thermal habitat use by juvenile lake whitefish and thermal niche overlap with exotic fishes that might prey on them. Final thermal preferenda of young lake whitefish varied inversely with fish size ranging from 16.8°C for fish averaging 1.9 g to 15.6°C for age-1 fish averaging 3.9 g. Final thermal preferenda were in agreement with the limited published information on temperature selection of juvenile lake whitefish in the laboratory and on thermal habitat use by wild, free-ranging populations in the Great Lakes.

The Geometric Factor of Electrostatic Plasma Analyzers: A Case Study from the Fast Plasma Investigation for the Magnetospheric Multiscale mission

NASA Technical Reports Server (NTRS)

Collinson, Glyn A.; Dorelli, John Charles; Avanov, Leon A.; Lewis, Gethyn R.; Moore, Thomas E.; Pollock, Craig; Kataria, Dhiren O.; Bedington, Robert; Arridge, Chris S.; Chornay, Dennis J.;

Introduction of Digital Computer Technology Into the Undergraduate Chemistry Laboratory. Final Technical Report.

ERIC Educational Resources Information Center

Perone, Sam P.

The objective of this project has been the development of a successful approach for the incorporation of on-line computer technology into the undergraduate chemistry laboratory. This approach assumes no prior programing, electronics or instrumental analysis experience on the part of the student; it does not displace the chemistry content with…

Writing Activities Embedded in Bioscience Laboratory Courses to Change Students' Attitudes and Enhance Their Scientific Writing

ERIC Educational Resources Information Center

Lee, Susan E.; Woods, Kyra J.; Tonissen, Kathryn F.

2011-01-01

We introduced writing activities into a project style third year undergraduate biomolecular science laboratory to assist the students to produce a final report in the form of a journal article. To encourage writing while the experimental work was proceeding, the embedded writing activities required ongoing analysis of experimental data. After…

Application of rapid onsite PCR (TaqMan) for Phytophthora ramorum under U.S. conditions

Treesearch

Kelvin Hughes; Jenny Tomlinson; Neil Boonham; Kelly Ivors; Matteo Garbelotto; Ian Barker

2006-01-01

Currently, diagnosis of Phytophthora ramorum involves sending samples to a laboratory for traditional isolation and morphological characterisation, and/or PCR analysis. This can take as long as 2 weeks from sampling to final diagnosis. However, the Plant Health Group, Central Science Laboratory, has produced on-site DNA extraction and real-time PCR (...

Exit competencies in pathology and laboratory medicine for graduating medical students: the Canadian approach.

PubMed

Ford, Jason; Pambrun, Chantale

2015-05-01

Physicians in every medical and surgical field must be able to use pathology concepts and skills in their practice: for example, they must order and interpret the correct laboratory tests, they must use their understanding of pathogenesis to diagnose and treat, and they must work with the laboratory to care for their patients. These important concepts and skills may be ignored by medical schools and even national/international organizations setting graduation expectations for medical students. There is an evolving international consensus about the importance of exit competencies for medical school graduates, which define the measurable or observable behaviors each graduate must be able to demonstrate. The Canadian Association of Pathologists (CAP) Education Group set out to establish the basic competencies in pathology and laboratory medicine which should be expected of every medical graduate: not competencies for pathologists, but for medical graduates who intend to enter any residency program. We defined 4 targets for pathology and laboratory medicine exit competencies: that they represent only measurable behaviors, that they be clinically focused, that they be generalizable to every medical graduate, and that the final competency document be user-friendly. A set of competencies was developed iteratively and underwent final revision at the 2012 CAP annual meeting. These competencies were subsequently endorsed by the CAP executive and the Canadian Leadership Council on Laboratory Medicine. This clinically focused consensus document provides the first comprehensive list of exit competencies in pathology and laboratory medicine for undergraduate medical education. Copyright © 2015 Elsevier Inc. All rights reserved.

Optimization of Methylphenidate Extended-Release Chewable Tablet Dose in Children with ADHD: Open-Label Dose Optimization in a Laboratory Classroom Study.

PubMed

Wigal, Sharon B; Childress, Ann; Berry, Sally A; Belden, Heidi W; Chappell, Phillip; Wajsbrot, Dalia B; Nagraj, Praneeta; Abbas, Richat; Palumbo, Donna

2018-06-01

To examine methylphenidate extended-release chewable tablets (MPH ERCT) dose patterns, attention-deficit/hyperactivity disorder (ADHD) symptom scores, and safety during the 6-week, open-label (OL) dose-optimization period of a phase 3, laboratory classroom study. Boys and girls (6-12 years) diagnosed with ADHD were enrolled. MPH ERCT was initiated at 20 mg/day; participants were titrated in 10-20 mg/day increments weekly based on efficacy and tolerability (maximum dose, 60 mg/day). Dose-optimization period efficacy assessments included the ADHD Rating Scale (ADHD-RS-IV), analyzed by week in a post hoc analysis using a mixed-effects model for repeated measures with final optimized dose (20, 30/40, or 50/60 mg), visit, final optimized dose and visit interaction, and baseline score as terms. Adverse events (AEs) and concomitant medications were collected throughout the study. Mean MPH ERCT daily dose increased weekly from 29.4 mg/day after the first dose adjustment at week 1 (n = 90) to 42.8 mg/day after the final adjustment at week 5 (n = 86). Final optimized MPH ERCT dose ranged from 20 to 60 mg/day. Mean final optimized MPH ERCT dose ranged from 40.0 mg/day in 6-8 year-old participants to 44.8 mg/day for 11-12 year-old participants. There was a progressive decrease in mean (standard deviation) ADHD-RS-IV total score from 40.1 (8.72) at baseline to 12.4 (7.88) at OL week 5, with similar improvement patterns for hyperactivity/impulsivity and inattentiveness subscale scores. Participants optimized to MPH ERCT 50/60 mg/day had a significantly higher mean (standard error) ADHD-RS-IV score at baseline compared with participants optimized to MPH ERCT 20 mg/day (42.4 [1.34] vs. 35.1 [2.55]; p = 0.013). Treatment-emergent AEs were reported by 65/90 (72.2%) participants in the dose-optimization period. Dose-optimization period results describing relationships between change in ADHD symptom scores and final optimized MPH ERCT dose will be valuable for clinicians optimizing MPH ERCT dose.

A Dual Case Study: Students' Perceptions, Self-Efficacy and Understanding of the Nature of Science in Varied Introductory Biology Laboratories

NASA Astrophysics Data System (ADS)

Quigley, Dena Beth Boans

Since World War II, science education has been at the forefront of curricular reforms. Although the philosophical approach to science education has changed numerous times, the importance of the laboratory has not waned. A laboratory is meant to allow students to encounter scientific concepts in a very real, hands-on way so that they are able to either recreate experiments that have given rise to scientific theories or to use science to understand a new idea. As the interactive portion of science courses, the laboratory should not only reinforce conceptual ideas, but help students to understand the process of science and interest them in learning more about science. However, most laboratories have fallen into a safe pattern having teachers and students follow a scientific recipe, removing the understanding of and interest in science for many participants. In this study, two non-traditional laboratories are evaluated and compared with a traditional laboratory in an effort to measure student satisfaction, self-efficacy, attitudes towards science, and finally their epistemology of the nature of science (NOS). Students in all populations were administered a survey at the beginning and the end of their spring 2016 laboratory, and the survey was a mixture of qualitative questions and quantitative instruments. Overall, students who participated in one of the non-traditional labs rated their satisfaction higher and used affirming supportive statements. They also had significant increases in self-efficacy from pre to post, while the students in the traditional laboratory had a significant decrease. The students in the traditional laboratory had significant changed in attitudes towards science, as did the students in one of the non-traditional laboratories. All students lacked a firm grasp of the tenets of NOS, although one laboratory that includes explicit discussions of NOS saw improvement in at least on tenet. Data for two non-major biology laboratory populations was collected, but only qualitative analysis was conducted as their participation was very low. Unfortunately, no direct comparisons could be made between biology majors and non-majors.

Adult encephalitis surveillance: experiences from an Australian prospective sentinel site study.

PubMed

Eastwood, K; Paterson, B J; Levi, C; Givney, R; Loewenthal, M; DE Malmanche, T; Lai, K; Granerod, J; Durrheim, D N

2015-11-01

Few countries routinely collect comprehensive encephalitis data, yet understanding the epidemiology of this condition has value for clinical management, detecting novel and emerging pathogens, and guiding timely public health interventions. When this study was conducted there was no standardized diagnostic algorithm to aid identification of encephalitis or systematic surveillance for adult encephalitis. In July 2012 we tested three pragmatic surveillance options aimed at identifying possible adult encephalitis cases admitted to a major Australian hospital: hospital admissions searches, clinician notifications and laboratory test alerts (CSF herpes simplex virus requests). Eligible cases underwent structured laboratory investigation and a specialist panel arbitrated on the final diagnosis. One hundred and thirteen patients were initially recruited into the 10-month study; 20/113 (18%) met the study case definition, seven were diagnosed with infectious or immune-mediated encephalitis and the remainder were assigned alternative diagnoses. The laboratory alert identified 90% (102/113) of recruited cases including six of the seven cases of confirmed encephalitis suggesting that this may be a practical data source for case ascertainment. The application of a standardized diagnostic algorithm and specialist review by an expert clinical panel aided diagnosis of patients with encephalitis.

National continuous surveys on internal quality control for HbA1c in 306 clinical laboratories of China from 2012 to 2016: Continual improvement.

PubMed

Li, Tingting; Wang, Wei; Zhao, Haijian; He, Falin; Zhong, Kun; Yuan, Shuai; Wang, Zhiguo

2017-09-01

This study aimed to evaluate whether the quality performance of clinical laboratories in China has been greatly improved and whether Internal Quality Control (IQC) practice of HbA1c has also been changed since National Center for Clinical Laboratories (NCCL) of China organized laboratories to report IQC data for HbA1c in 2012. Internal Quality Control information of 306 External Quality Assessment (EQA) participant laboratories which kept reporting IQC data in February from 2012 to 2016 were collected by Web-based EQA system. Then percentages of laboratories meeting four different imprecision specifications for current coefficient of variations (CVs) of HbA1c measurements were calculated. Finally, we comprehensively analyzed analytical systems and IQC practice of HbA1c measurements. The current CVs of HbA1c tests have decreased significantly from 2012 to 2016. And percentages of laboratories meeting four imprecision specifications for CVs all showed the increasing tendency year by year. As for analytical system, 52.1% (159/306) laboratories changed their systems with the change in principle of assay. And many laboratories began to use cation exchange high-performance liquid chromatography (CE-HPLC) instead of Immunoturbidimetry, because CE-HPLC owed a lower intra-laboratory CVs. The data of IQC practice, such as IQC rules and frequency, also showed significant variability among years with overall tendency of meeting requirements. The imprecision performance of HbA1c tests has been improved in these 5 years with the change in IQC practice, but it is still disappointing in China. Therefore, laboratories should actively find existing problems and take action to promote performance of HbA1c measurements. © 2016 Wiley Periodicals, Inc.

Mass: 100 mg, 10 g, 100 g, 1 kg, 10 kg and 50 kg

NASA Astrophysics Data System (ADS)

Kaçmaz, Sevda; Davidson, Stuart

2017-01-01

Bilateral mass comparison of mass standards of 100 mg, 2 g, 20 g, 500 g and 10 kg was carried out in 2011 to 2012 between UME and NPL. UME was the pilot laboratory. For all mass standards, the results show adequate agreement between the laboratories. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Final Report for the Arroyo Las Positas Maintenance Impact Study, Lawrence Livermore National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

van Hattem, M; Paterson, L

2006-01-12

In 2000, the Lawrence Livermore National Laboratory's (LLNL) Environmental Protection Department, in coordination with Plant Engineering (PE), began dredging sections of the Arroyo Las Positas (ALP) to alleviate concerns about flooding of sensitive facilities within the mainsite of Lawrence Livermore National Laboratory. In order to reduce potential impacts on the federally threatened California red-legged frog (Rana aurora draytonii), LLNL proposed to dredge sections of the ALP in a ''checkerboard pattern'', resulting in a mosaic of open water habitat and vegetated sections (Figure 1). The Arroyo Las Positas Management Plan (Plan) was coordinated with both state and federal agencies including themore » U.S. Fish and Wildlife Service (USFWS), California Department of Fish and Game (CDF&G), San Francisco Regional Water Quality Control Board (SFRWQCB), and the Army Corp of Engineers (ACOE). Water Discharge Requirements (WDRs) were issued for this project on December 30, 1999 (Order No. 99-086) by the SFRWQCB. Provision 19 of the WDRs outlined a five-year (2000 through 2004) Maintenance Impact Study (MIS) that LLNL began in coordination with dredging work that was conducted as part of the Arroyo Las Positas Management Plan. Provision 20 of these WDRs requires LLNL to submit a final report of the results of the Maintenance Impact Study for this project to the SFRWQCB. The purpose of this report is to present the results of the Maintenance Impact Study for Arroyo Las Positas and meet the requirements of Provision 20. A description of the annual monitoring included in this Maintenance Impact Study is included in the methods section of this report. Initially the Plan called for dredging the entire length of the Arroyo Las Positas (approximately 6,981 linear feet) over a 5-year period to minimize temporal impacts on the California red-legged frog. Dredging occurred in 2000 ({approx}1,300 ft.), 2001 ({approx}800 ft.), and 2002 ({approx}1,200 ft.), which constituted approximately 3,300 ft., or roughly half of the entire Plan (Figure 2). Logistical challenges and unanticipated cost influenced the decision to terminate the project prior to completion, and re-evaluate the long-term management goals for the ALP. No dredging was conducted in the final two years of the plan (2003 and 2004).« less

Electrochemical Processes for In-Situ Treatment of Contaminated Soils - Final Report - 09/15/1996 - 01/31/2001

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, Chin-Pao

2001-05-31

This project will study electrochemical processes for the in situ treatment of soils contaminated by mixed wastes, i.e., organic and inorganic. Soil samples collected form selected DOE waste sites will be characterized for specific organic and metal contaminants and hydraulic permeability. The soil samples are then subject to desorption experiments under various physical-chemical conditions such as pH and the presence of surfactants. Batch electro-osmosis experiments will be conducted to study the transport of contaminants in the soil-water systems. Organic contaminants that are released from the soil substrate will be treated by an advanced oxidation process, i.e., electron-Fantan. Finally, laboratory reactormore » integrating the elector-osmosis and elector-Fantan processes will be used to study the treatment of contaminated soil in situ.« less

New virtual laboratories presenting advanced motion control concepts

NASA Astrophysics Data System (ADS)

Goubej, Martin; Krejčí, Alois; Reitinger, Jan

2015-11-01

The paper deals with development of software framework for rapid generation of remote virtual laboratories. Client-server architecture is chosen in order to employ real-time simulation core which is running on a dedicated server. Ordinary web browser is used as a final renderer to achieve hardware independent solution which can be run on different target platforms including laptops, tablets or mobile phones. The provided toolchain allows automatic generation of the virtual laboratory source code from the configuration file created in the open- source Inkscape graphic editor. Three virtual laboratories presenting advanced motion control algorithms have been developed showing the applicability of the proposed approach.

Mars Science Laboratory's Descent Stage

NASA Technical Reports Server (NTRS)

2008-01-01

This portion of NASA's Mars Science Laboratory, called the descent stage, does its main work during the final few minutes before touchdown on Mars.

The descent stage will provide rocket-powered deceleration for a phase of the arrival at Mars after the phases using the heat shield and parachute. When it nears the surface, the descent stage will lower the rover on a bridle the rest of the way to the ground.

The Mars Science Laboratory spacecraft is being assembled and tested for launch in 2011.

This image was taken at NASA's Jet Propulsion Laboratory, Pasadena, Calif., which manages the Mars Science Laboratory Mission for NASA's Science Mission Directorate, Washington. JPL is a division of the California Institute of Technology.

Treatment of landfill leachate by the Fenton process.

PubMed

Deng, Yang; Englehardt, James D

2006-12-01

In recent years, studies of leachate treatment by conventional Fenton, photo-Fenton and electro-Fenton processes have indicated that these methods can effectively reduce concentrations of organic contaminants and color. In addition, the process can increase the biodegradable fraction of organic constituents in leachate, particularly in mature or biologically recalcitrant leachate. Oxidation and coagulation both play important roles in the removal of organics. Initial pH, dosages of Fenton reagents, aeration, final pH, reagent addition mode, temperature, and UV irradiation may influence final treatment efficiency. In this paper, current knowledge of performance and economics of Fenton processes for treatment of landfill leachate as reported for laboratory, pilot and full-scale studies is reviewed, with the conclusion that the Fenton process is an important and competitive technology for the treatment or pretreatment of landfill leachate.

Final report on APMP.T-K7 key comparison of water triple point cells

NASA Astrophysics Data System (ADS)

Tsai, S. F.; White, R.; Tamba, J.; Yamazawa, K.; Ho, M. K.; Tsui, C. M.; Zaid, G.; Achmadi, A.; Gam, K. S.; Othman, H.; Ali, N. M.; Yuan, K. H.; Shaochun, Y.; Liedberg, H.; Yaokulbodee, C.

2016-01-01

APMP.T-K7, was held from February 2008 to September 2009 to compare the national realizations of the water triple point among eleven NMIs. To reach the objective, each participating laboratory sent a transfer cell to CMS and stated a value for the temperature difference of the transfer cell, relative to the corresponding national standard, representing 273.16 K. CMS (Taiwan) organized the comparison, with the support from co-pilot institutes MSL (New Zealand) and NMIJ (Japan). The other eight participating laboratories included NMIA, SCL, KIM-LIPI, KRISS, NMIM/SIRIM, NMC, NMISA, and NIMT. This report presents the results of the TPW comparison, gives detailed information about the measurements made at the CMS and at the participating laboratories, and aims to link the results of APMP.T-K7 to CCT-K7. The results of this key comparison are also represented in the form of degrees of equivalence for the purposes of the MRA. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCT, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Reactions and Assessments: Educational Laboratory Theatre Project, 1966-70. Final Report.

ERIC Educational Resources Information Center

Hoetker, James; And Others

The general plan of the 4-year (1966-1970) Educational Laboratory Theatre Project was to have theatre companies in Rhode Island, New Orleans, and Los Angeles give five matinee performances per week for high school students and three evening performances for adults in order to (1) make extensive use of professional theatre as an integral part of…

INTER LABORATORY COMBAT HELMET BLUNT IMPACT TEST METHOD COMPARISON

DTIC Science & Technology

2018-03-26

HELMET BLUNT IMPACT TEST METHOD COMPARISON by Tony J. Kayhart Charles A. Hewitt and Jonathan Cyganik March 2018 Final...Report March 2016 – August 2017 Approved for public release; distribution is unlimited U.S. Army Natick Soldier Research ...INTER-LABORATORY COMBAT HELMET BLUNT IMPACT TEST METHOD COMPARISON 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR

Evaluation of Title I Program, Community School Distrlct 31, New York City. 1978-79 School Year. Final Report, E.D.L. Reading Lab.

ERIC Educational Resources Information Center

Knight, Michael E.

This program was designed to improve reading skills and to provide intensive remediation for students in grades six through nine. Specialized materials and equipment were provided by Educational Development Laboratories (EDL). The EDL Reading Laboratory utilized the Learning 100 program, a multi-modality developmental and remedial program. Small…

FIELD CHECK MANUAL FOR LANGUAGE LABORATORIES, A SERIES OF TESTS WHICH A NON-TECHNICAL PERSON CAN CONDUCT TO VERIFY SPECIFICATIONS.

ERIC Educational Resources Information Center

GRITTNER, FRANK; PAVLAT, RUSSELL

IN ORDER TO ASSIST NON-TECHNICAL PEOPLE IN SCHOOLS TO CONDUCT A FIELD CHECK OF LANGUAGE LABORATORY EQUIPMENT BEFORE THEY MAKE FINAL PAYMENTS, THIS MANUAL OFFERS CRITERIA, TESTS, AND METHODS OF SCORING THE QUALITY OF THE EQUIPMENT. CHECKLISTS ARE PROVIDED FOR EVALUATING CONSOLE FUNCTIONS, TAPE RECORDERS, AMPLIFIERS, SOUND QUALITY (INCLUDING…

BIOMASSCOMP: Artificial Neural Networks and Neurocomputers

DTIC Science & Technology

1988-09-01

52 APPENDICES A. NTSU NEUROSCIENCE LABORATORY (30 pages) B. SOFTWARE LISTINGS (27 pages) 1. DTEST - Structure Function...neurocomputers normally proceeds by using the best available data from the neuroscience community to build and test computational models of the components...53 Mo BIOHASSCOM? PHASE I FINAL REPORT Page 54 APPENDIX A THE NORTH TEXAS STATE UNIVERSITY NEUROSCIENCE LABORATORY OF PROF. GUENTER W. GROSS Dr

The processing and collaborative assay of a reference endotoxin.

PubMed

Hochstein, H D; Mills, D F; Outschoorn, A S; Rastogi, S C

1983-10-01

A preparation of Escherichia coli bacterial endotoxin, the latest of successive lots drawn from bulk material which has been studied in laboratory tests and in animals and humans for suitability as a reference endotoxin, has been filled and lyophilized in a large number of vials. Details of its characterization, including stability studies, are given. A collaborative assay was conducted by 14 laboratories using gelation end-points with Limulus amebocyte lysates. Approximate continuity of the unit of potency with the existing national unit was achieved. The lot was made from the single final bulk but had to be freeze-dried in five sublimators. An assessment was therefore made for possible heterogeneity. The results indicate that the lot can be used as a large homogeneous quantity. The advantages of using it widely as a standard for endotoxins are discussed.

Transmutation studies at CEA in frame of the SPIN program objectives, results and future trends

DOE Office of Scientific and Technical Information (OSTI.GOV)

Salvatores, M.; Prunier, C.; Guerin, Y.

1995-10-01

In order to respond to the public concern about wastes and in particular the long-lived high level ones, a French law issued on December 30, 1991 identified the major objectives of research for the next fifteen years, before a new debate and possibly a decision on final wastes disposal in Parliament. These objectives are: (1) improvement of the wastes conditioning; (2) extraction and transmutation of the long-lived wastes in order to minimize their long term toxicity; (3) research performed in underground laboratories in order to characterize the capacity of geological structures to confine radioactive wastes (two sites have to bemore » selected for these underground laboratories, in concertation with the local population); (4) last, the study of conditioning and prolonged surface storage of wastes.« less

Human Behavioral Pharmacology, Past, Present, and Future: Symposium Presented at the 50th Annual Meeting of the Behavioral Pharmacology Society

PubMed Central

Comer, Sandra D.; Bickel, Warren K.; Yi, Richard; de Wit, Harriet; Higgins, Stephen T.; Wenger, Galen R.; Johanson, Chris-Ellyn; Kreek, Mary Jeanne

2010-01-01

A symposium held at the 50th annual meeting of the Behavioral Pharmacology Society in May 2007 reviewed progress in the human behavioral pharmacology of drug abuse. Studies on drug self-administration in humans are reviewed that assessed reinforcing and subjective effects of drugs of abuse. The close parallels observed between studies in humans and laboratory animals using similar behavioral techniques have broadened our understanding of the complex nature of the pharmacological and behavioral factors controlling drug self-administration. The symposium also addressed the role that individual differences, such as gender, personality, and genotype play in determining the extent of self-administration of illicit drugs in human populations. Knowledge of how these factors influence human drug self-administration has helped validate similar differences observed in laboratory animals. In recognition that drug self-administration is but one of many choices available in the lives of humans, the symposium addressed the ways in which choice behavior can be studied in humans. These choice studies in human drug abusers have opened up new and exciting avenues of research in laboratory animals. Finally, the symposium reviewed behavioral pharmacology studies conducted in drug abuse treatment settings and the therapeutic benefits that have emerged from these studies. PMID:20664330

Contribution to the Study of Ammonia Removal from Digestate by Struvite Precipitation

NASA Astrophysics Data System (ADS)

Vidlarova, P.; Heviankova, S.; Kyncl, M.

2017-10-01

This study deals with an issue of ammonia removal from anaerobic digestion’s by-product - digestate. The aim of the research is ammonia removal by chemical precipitation using the combination of Mg2+, NH4+ and PO43-ions in struvite (MgNH4PO4 . 6 H2O). Laboratory tests were carried out using the sample of digestate liquor. The final product of the treatment may have the potential to be used as a fertilizer.

Some aspects of dust-plasma interactions in the cosmic environment

NASA Technical Reports Server (NTRS)

Mendis, D. A.; Rosenberg, Marlene

1992-01-01

In this paper we present a brief, critical review of dust-plasma interactions in the cosmic environment, with emphasis on certain recent results. Both single-particle (e.g. gravitoelectrodynamics) and collective effects (e.g. appearance of new wave modes) are discussed and some areas in which further research is needed are pointed out. Finally the pressing need for laboratory studies, both to provide the necessary data for the theoretical studies and to test the predictions of these theories, is emphasized.

Focused Feasibility Study Final Field Sampling Plan

DTIC Science & Technology

1993-10-01

baseline of groundwater chemistry prior to commencing additional environmental investigations of the area. Work for Phase I of the FFS is designed lo...investigations and remedial feasibility investigations at Beach Point. The groundwater data will also be used to aid in the design of any groundwater extraction...approved laboratories. The analytical data will be the equivalent of EPA Level IV data. This level of data quality has been established for environmental

Agribusiness: Industry Study Final Report, AY 2003-2004, Seminar 1

DTIC Science & Technology

2004-01-01

vulnerability of our nation’s food supply to a potential biological attack, primarily due to inadequate governmental oversight. He states, "The Food and Drug...national laboratory system to assist with chemical, biological , and radiological agent identification and analysis. Following the passage of the...Genetically Modified Foods,” June 2003. Chalk, Peter, “Hitting America’s Soft Underbelly: The Potential Threat of Deliberate Biological Attacks

SELECTIVE DISSEMINATION OF INFORMATION (SDI). VOLUME I, PILOT TEST AT U.S. ARMY NATICK LABORATORIES. FINAL REPORT. ARMY TECHNICAL LIBRARY IMPROVEMENT STUDIES (ATLIS), REPORT NO. 15.

ERIC Educational Resources Information Center

BIVONA, WILLIAM A.

THIS VOLUME PRESENTS THE RESULTS OF A NINE-MONTH TEST OF A PROTOTYPE SELECTIVE DISSEMINATION OF INFORMATION (SDI) SYSTEM DEVELOPED FOR THE ARMY TECHNICAL LIBRARIES. DURING THE PILOT TEST ONE THOUSAND DOCUMENTS WERE CATALOGED, INDEXED, AND DISSEMINATED TO TWENTY-FIVE SCIENTIFIC AND TECHNICAL PERSONNEL. MATCHING OF THE INTEREST PROFILES OF THESE…

New precision measurements of free neutron beta decay with cold neutrons

DOE PAGES

Baeßler, Stefan; Bowman, James David; Penttilä, Seppo I.; ...

2014-10-14

Precision measurements in free neutron beta decay serve to determine the coupling constants of beta decay, and offer several stringent tests of the standard model. This study describes the free neutron beta decay program planned for the Fundamental Physics Beamline at the Spallation Neutron Source at Oak Ridge National Laboratory, and finally puts it into the context of other recent and planned measurements of neutron beta decay observables.

Experimental, Theoretical and Computational Studies of Plasma-Based Concepts for Future High Energy Accelerators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Joshi, Chan; Mori, W.

2013-10-21

This is the final report on the DOE grant number DE-FG02-92ER40727 titled, “Experimental, Theoretical and Computational Studies of Plasma-Based Concepts for Future High Energy Accelerators.” During this grant period the UCLA program on Advanced Plasma Based Accelerators, headed by Professor C. Joshi has made many key scientific advances and trained a generation of students, many of whom have stayed in this research field and even started research programs of their own. In this final report however, we will focus on the last three years of the grant and report on the scientific progress made in each of the four tasksmore » listed under this grant. Four tasks are focused on: Plasma Wakefield Accelerator Research at FACET, SLAC National Accelerator Laboratory, In House Research at UCLA’s Neptune and 20 TW Laser Laboratories, Laser-Wakefield Acceleration (LWFA) in Self Guided Regime: Experiments at the Callisto Laser at LLNL, and Theory and Simulations. Major scientific results have been obtained in each of the four tasks described in this report. These have led to publications in the prestigious scientific journals, graduation and continued training of high quality Ph.D. level students and have kept the U.S. at the forefront of plasma-based accelerators research field.« less

Modification of heterogeneous chemistry by complex substrate morphology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Henson, B.F.; Buelow, S.J.; Robinson, J.M.

1998-12-31

This is the final report of a one-year, Laboratory Directed Research and Development (LDRD) project at Los Alamos National Laboratory (LANL). Chemistry in many environmental systems is determined at some stage by heterogeneous reaction with a surface. Typically the surface exists as a dispersion or matrix of particulate matter or pores, and a determination of the heterogeneous chemistry of the system must address the extent to which the complexity of the environmental surface affects the reaction rates. Reactions that are of current interest are the series of chlorine nitrate reactions important in polar ozone depletion. The authors have applied surfacemore » spectroscopic techniques developed at LANL to address the chemistry of chlorine nitrate reactions on porous nitric and sulfuric acid ice surfaces as a model study of the measurement of complex, heterogeneous reaction rates. The result of the study is an experimental determination of the surface coverage of one adsorbed reagent and a mechanism of reactivity based on the dependence of this coverage on temperature and vapor pressure. The resulting mechanism allows the first comprehensive modeling of chlorine nitrate reaction probability data from several laboratories.« less

An educational laboratory virtual instrumentation suite assisted experiment for studying fundamentals of series resistance-inductance-capacitance circuit

NASA Astrophysics Data System (ADS)

Rana, K. P. S.; Kumar, Vineet; Mendiratta, Jatin

2017-11-01

One of the most elementary concepts in freshmen Electrical Engineering subject comprises the Resistance-Inductance-Capacitance (RLC) circuit fundamentals, that is, their time and frequency domain responses. For a beginner, generally, it is difficult to understand and appreciate the step and the frequency responses, particularly the resonance. This paper proposes a student-friendly teaching and learning approach by inculcating the multifaceted versatile software LabVIEWTM along with the educational laboratory virtual instrumentation suite hardware, for studying the RLC circuit time and frequency domain responses. The proposed approach has offered an interactive laboratory experiment where students can model circuits in simulation and hardware circuits on prototype board, and then compare their performances. The theoretical simulations and the obtained experimental data are found to be in very close agreement, thereby enhancing the conviction of students. Finally, the proposed methodology was also subjected to the assessment of learning outcomes based on student feedback, and an average score of 8.05 out of 10 with a standard deviation of 0.471 was received, indicating the overall satisfaction of the students.

Inclusive π+d →p (η p ) process and the η N scattering length

NASA Astrophysics Data System (ADS)

Garcilazo, Humberto

2018-02-01

The cross section of the inclusive process π+d →p (η p ) is calculated as a function of the η p invariant mass when the detected proton is moving in the forward direction. The incident pion has a momentum of plab=898.47 MeV/c for which the η p pair are left at rest in the laboratory system which allows one to study the effect of the η p →η p final-state interaction in the region of the N (1535 ) S11 resonance. The sensitivity of the inclusive cross section to different parametrizations of the η N final-state interaction is discussed.

Collaborative Testing in Practical Laboratories: An Effective Teaching-Learning Method in Histology.

PubMed

Guo, Yuping; Li, Enzhong

2016-01-01

This article presents an experimental teaching and learning program used in histology with first-year students in the second term in the Faculty of Biology at Huanghuai University, China. Eighty-six students were divided randomly into two groups (n=43 per group). Tests were conducted at the end of each practical laboratory (10 laboratories in total) in which collaborative testing was used in the experimental group and traditional testing in the control group. To assess achievement, a final examination in histology was carried out at the end of the course. To determine students' attitude to the teaching styles, a questionnaire survey was conducted at the end of the term. Results showed that students preferred the collaborative testing format. In the experimental group, students' scores were significantly higher than those of students in the control group in final examinations. These findings indicate that collaborative testing enhances student learning and understanding of the material taught, and suggest that collaborative testing is an effective teaching-learning method in histology.

Tools to minimize interlaboratory variability in vitellogenin gene expression monitoring programs

USGS Publications Warehouse

Jastrow, Aaron; Gordon, Denise A.; Auger, Kasie M.; Punska, Elizabeth C.; Arcaro, Kathleen F.; Keteles, Kristen; Winkelman, Dana L.; Lattier, David; Biales, Adam; Lazorchak, James M.

2017-01-01

The egg yolk precursor protein vitellogenin is widely used as a biomarker of estrogen exposure in male fish. However, standardized methodology is lacking and little is known regarding the reproducibility of results among laboratories using different equipment, reagents, protocols, and data analysis programs. To address this data gap we tested the reproducibility across laboratories to evaluate vitellogenin gene (vtg) expression and assessed the value of using a freely available software data analysis program. Samples collected from studies of male fathead minnows (Pimephales promelas) exposed to 17α-ethinylestradiol (EE2) and minnows exposed to processed wastewater effluent were evaluated for vtg expression in 4 laboratories. Our results indicate reasonable consistency among laboratories if the free software for expression analysis LinRegPCR is used, with 3 of 4 laboratories detecting vtg in fish exposed to 5 ng/L EE2 (n = 5). All 4 laboratories detected significantly increased vtg levels in 15 male fish exposed to wastewater effluent compared with 15 male fish held in a control stream. Finally, we were able to determine that the source of high interlaboratory variability from complementary deoxyribonucleic acid (cDNA) to quantitative polymerase chain reaction (qPCR) analyses was the expression analysis software unique to each real-time qPCR machine. We successfully eliminated the interlaboratory variability by reanalyzing raw fluorescence data with independent freeware, which yielded cycle thresholds and polymerase chain reaction (PCR) efficiencies that calculated results independently of proprietary software. Our results suggest that laboratories engaged in monitoring programs should validate their PCR protocols and analyze their gene expression data following the guidelines established in the present study for all gene expression biomarkers. 

TEAM TRAINING. FINAL TECHNICAL REPORT FEBRUARY 1966-FEBRUARY 1967.

ERIC Educational Resources Information Center

BRIGGS, GEORGE E.; JOHNSTON, WILLIAM A.

THIS IS THE FINAL REPORT ON A FOUR-YEAR PROGRAM OF LABORATORY RESEARCH ON TEAM TRAINING IN A COMBAT INFORMATION CENTER (CIC) CONTEXT. THE RESEARCH LITERATURE ON TEAM TRAINING IS REVIEWED, AND A SET OF CONCLUSIONS IS DRAWN WITH REGARD TO TEAM PERFORMANCE AS A FUNCTION OF TASK, TRAINING, AND COMMUNICATIONS VARIABLES. IN ADDITION, THE IMPLICATIONS…

Asynchronous automated electronic laboratory result notifications: a systematic review.

PubMed

Slovis, Benjamin H; Nahass, Thomas A; Salmasian, Hojjat; Kuperman, Gilad; Vawdrey, David K

2017-11-01

To systematically review the literature pertaining to asynchronous automated electronic notifications of laboratory results to clinicians. PubMed, Web of Science, and the Cochrane Collaboration were queried for studies pertaining to automated electronic notifications of laboratory results. A title review was performed on the primary results, with a further abstract review and full review to produce the final set of included articles. The full review included 34 articles, representing 19 institutions. Of these, 19 reported implementation and design of systems, 11 reported quasi-experimental studies, 3 reported a randomized controlled trial, and 1 was a meta-analysis. Twenty-seven articles included alerts of critical results, while 5 focused on urgent notifications and 2 on elective notifications. There was considerable variability in clinical setting, system implementation, and results presented. Several asynchronous automated electronic notification systems for laboratory results have been evaluated, most from >10 years ago. Further research on the effect of notifications on clinicians as well as the use of modern electronic health records and new methods of notification is warranted to determine their effects on workflow and clinical outcomes. © The Author 2017. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com

[Some notes on the history of the experimental surgery laboratory. Reflections on its relevance in education and surgical research].

PubMed

de la Garza-Rodea, Anabel Sofía; Padilla-Sánchez, Luis; de la Garza-Aguilar, Javier; Neri-Vela, Rolando

2007-01-01

The progress of medicine has largely been due to research, and for surgery, in particular, the experimental surgical laboratory has been considered fundamental to the surgeon's education. In this study, a general view of experimental surgery is given in animal models based on bioethical norms as well as to design, create and apply different surgical procedures before performing in humans. Experimental surgery also facilitates surgical teaching and promotes the surgeon's scientific reasoning. Methods. This is a retrospective and descriptive study. Data were collected from direct and indirect sources of available publications on the historical, bioethical and educational aspects of medicine, focusing on surgery. The important facts corresponding to the field of experimental surgery and applicable in Mexico were selected. Concepts of experimental surgical models and of the experimental surgery laboratory were described. Bioethical considerations are emphasized for care of experimental animals. Finally, this work focuses on the importance of surgical experimentation in current and future development of the surgical researcher. Conclusions. Experimentation with animal models in a surgical laboratory is essential for surgical teaching and promotes development of the scientific thought in the surgeon. It is necessary for surgical research and is fundamental for making progress in surgery, treatment and medicine as science.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Watts, Bernadette M.; Collis, Samuel Scott; Ceballos, Deanna Rose

This report summarizes the activities of the Computer Science Research Institute (CSRI) at Sandia National Laboratories during the period January 1, 2005 to December 31, 2005. During this period, the CSRI hosted 182 visitors representing 83 universities, companies and laboratories. Of these, 60 were summer students or faculty. The CSRI partially sponsored 2 workshops and also organized and was the primary host for 3 workshops. These 3 CSRI sponsored workshops had 105 participants, 78 from universities, companies and laboratories, and 27 from Sandia. Finally, the CSRI sponsored 12 long-term collaborative research projects and 3 Sabbaticals.

Tank 241-AP-105, cores 208, 209 and 210, analytical results for the final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nuzum, J.L.

1997-10-24

This document is the final laboratory report for Tank 241-AP-105. Push mode core segments were removed from Risers 24 and 28 between July 2, 1997, and July 14, 1997. Segments were received and extruded at 222-S Laboratory. Analyses were performed in accordance with Tank 241-AP-105 Push Mode Core Sampling and Analysis Plan (TSAP) (Hu, 1997) and Tank Safety Screening Data Quality Objective (DQO) (Dukelow, et al., 1995). None of the subsamples submitted for total alpha activity (AT), differential scanning calorimetry (DSC) analysis, or total organic carbon (TOC) analysis exceeded the notification limits as stated in TSAP and DQO. The statisticalmore » results of the 95% confidence interval on the mean calculations are provided by the Tank Waste Remediation Systems Technical Basis Group, and are not considered in this report. Appearance and Sample Handling Two cores, each consisting of four segments, were expected from Tank 241-AP-105. Three cores were sampled, and complete cores were not obtained. TSAP states core samples should be transported to the laboratory within three calendar days from the time each segment is removed from the tank. This requirement was not met for all cores. Attachment 1 illustrates subsamples generated in the laboratory for analysis and identifies their sources. This reference also relates tank farm identification numbers to their corresponding 222-S Laboratory sample numbers.« less

KSC-2009-2178

NASA Image and Video Library

2009-03-19

CAPE CANAVERAL, Fla. – The Materials Science Research Rack-1, or MSRR-1, arrived at NASA's Kennedy Space Center in Florida for final flight preparations. The size of a large refrigerator, MSRR-1 is 6 feet high, 3.5 feet wide and 40 inches deep and weighs about 1 ton. MSRR-1 is the payload for the STS-128 mission targeted to launch in August. The rack will be installed in the Leonardo Multi-Purpose Logistics Module for transport to the International Space Station . After arriving at the station, the rack will be housed in the U.S. Destiny laboratory. MSRR-1 will allow for study of a variety of materials including metals, ceramics, semiconductor crystals and glasses onboard the orbiting laboratory. Photo credit: NASA/Jim Grossmann

KSC-2009-2179

NASA Image and Video Library

2009-03-19

CAPE CANAVERAL, Fla. – At NASA's Kennedy Space Center in Florida, a technician checks out the Materials Science Research Rack-1, or MSRR-1, which will undergo final flight preparations. The size of a large refrigerator, MSRR-1 is 6 feet high, 3.5 feet wide and 40 inches deep and weighs about 1 ton. MSRR-1 is the payload for the STS-128 mission targeted to launch in August. The rack will be installed in the Leonardo Multi-Purpose Logistics Module for transport to the International Space Station . After arriving at the station, the rack will be housed in the U.S. Destiny laboratory. MSRR-1 will allow for study of a variety of materials including metals, ceramics, semiconductor crystals and glasses onboard the orbiting laboratory. Photo credit: NASA/Jim Grossmann

Improving Online Interactions: Lessons from an Online Anatomy Course with a Laboratory for Undergraduate Students.

PubMed

Attardi, Stefanie M; Barbeau, Michele L; Rogers, Kem A

2018-03-01

An online section of a face-to-face (F2F) undergraduate (bachelor's level) anatomy course with a prosection laboratory was offered in 2013-2014. Lectures for F2F students (353) were broadcast to online students (138) using Blackboard Collaborate (BBC) virtual classroom. Online laboratories were offered using BBC and three-dimensional (3D) anatomical computer models. This iteration of the course was modified from the previous year to improve online student-teacher and student-student interactions. Students were divided into laboratory groups that rotated through virtual breakout rooms, giving them the opportunity to interact with three instructors. The objectives were to assess student performance outcomes, perceptions of student-teacher and student-student interactions, methods of peer interaction, and helpfulness of the 3D computer models. Final grades were statistically identical between the online and F2F groups. There were strong, positive correlations between incoming grade average and final anatomy grade in both groups, suggesting prior academic performance, and not delivery format, predicts anatomy grades. Quantitative student perception surveys (273 F2F; 101 online) revealed that both groups agreed they were engaged by teachers, could interact socially with teachers and peers, and ask them questions in both the lecture and laboratory sessions, though agreement was significantly greater for the F2F students in most comparisons. The most common methods of peer communication were texting, Facebook, and meeting F2F. The perceived helpfulness of the 3D computer models improved from the previous year. While virtual breakout rooms can be used to adequately replace traditional prosection laboratories and improve interactions, they are not equivalent to F2F laboratories. Anat Sci Educ. © 2018 American Association of Anatomists. © 2018 American Association of Anatomists.

[Laboratory medicine in the obligatory postgraduate clinical training system--common clinical training program in the department of laboratory medicine in our prefectural medical university hospital].

PubMed

Okamoto, Yasuyuki

2003-04-01

I propose a postgraduate common clinical training program to be provided by the department of laboratory medicine in our prefectural medical university hospital. The program has three purposes: first, mastering basic laboratory tests; second, developing the skills necessary to accurately interpret laboratory data; third, learning specific techniques in the field of laboratory medicine. For the first purpose, it is important that medical trainees perform testing of their own patients at bedside or in the central clinical laboratory. When testing at the central clinical laboratory, instruction by expert laboratory technicians is helpful. The teaching doctors in the department of laboratory medicine are asked to advise the trainees on the interpretation of data. Consultation will be received via interview or e-mail. In addition, the trainees can participate in various conferences, seminars, and meetings held at the central clinical laboratory. Finally, in order to learn specific techniques in the field of laboratory medicine, several special courses lasting a few months will be prepared. I think this program should be closely linked to the training program in internal medicine.

PANIC: A General-purpose Panoramic Near-infrared Camera for the Calar Alto Observatory

NASA Astrophysics Data System (ADS)

Cárdenas Vázquez, M.-C.; Dorner, B.; Huber, A.; Sánchez-Blanco, E.; Alter, M.; Rodríguez Gómez, J. F.; Bizenberger, P.; Naranjo, V.; Ibáñez Mengual, J.-M.; Panduro, J.; García Segura, A. J.; Mall, U.; Fernández, M.; Laun, W.; Ferro Rodríguez, I. M.; Helmling, J.; Terrón, V.; Meisenheimer, K.; Fried, J. W.; Mathar, R. J.; Baumeister, H.; Rohloff, R.-R.; Storz, C.; Verdes-Montenegro, L.; Bouy, H.; Ubierna, M.; Fopp, P.; Funke, B.

2018-02-01

PANIC7 is the new PAnoramic Near-Infrared Camera for Calar Alto and is a project jointly developed by the MPIA in Heidelberg, Germany, and the IAA in Granada, Spain, for the German-Spanish Astronomical Center at Calar Alto Observatory (CAHA; Almería, Spain). This new instrument works with the 2.2 m and 3.5 m CAHA telescopes covering a field of view of 30 × 30 arcmin and 15 × 15 arcmin, respectively, with a sampling of 4096 × 4096 pixels. It is designed for the spectral bands from Z to K S , and can also be equipped with narrowband filters. The instrument was delivered to the observatory in 2014 October and was commissioned at both telescopes between 2014 November and 2015 June. Science verification at the 2.2 m telescope was carried out during the second semester of 2015 and the instrument is now at full operation. We describe the design, assembly, integration, and verification process, the final laboratory tests and the PANIC instrument performance. We also present first-light data obtained during the commissioning and preliminary results of the scientific verification. The final optical model and the theoretical performance of the camera were updated according to the as-built data. The laboratory tests were made with a star simulator. Finally, the commissioning phase was done at both telescopes to validate the camera real performance on sky. The final laboratory test confirmed the expected camera performances, complying with the scientific requirements. The commissioning phase on sky has been accomplished.

Resolving Complex Research Data Management Issues in Biomedical Laboratories: Qualitative Study of an Industry-Academia Collaboration

PubMed Central

Myneni, Sahiti; Patel, Vimla L.; Bova, G. Steven; Wang, Jian; Ackerman, Christopher F.; Berlinicke, Cynthia A.; Chen, Steve H.; Lindvall, Mikael; Zack, Donald J.

2016-01-01

This paper describes a distributed collaborative effort between industry and academia to systematize data management in an academic biomedical laboratory. Heterogeneous and voluminous nature of research data created in biomedical laboratories make information management difficult and research unproductive. One such collaborative effort was evaluated over a period of four years using data collection methods including ethnographic observations, semi-structured interviews, web-based surveys, progress reports, conference call summaries, and face-to-face group discussions. Data were analyzed using qualitative methods of data analysis to 1) characterize specific problems faced by biomedical researchers with traditional information management practices, 2) identify intervention areas to introduce a new research information management system called Labmatrix, and finally to 3) evaluate and delineate important general collaboration (intervention) characteristics that can optimize outcomes of an implementation process in biomedical laboratories. Results emphasize the importance of end user perseverance, human-centric interoperability evaluation, and demonstration of return on investment of effort and time of laboratory members and industry personnel for success of implementation process. In addition, there is an intrinsic learning component associated with the implementation process of an information management system. Technology transfer experience in a complex environment such as the biomedical laboratory can be eased with use of information systems that support human and cognitive interoperability. Such informatics features can also contribute to successful collaboration and hopefully to scientific productivity. PMID:26652980

Students' perceptions of academic dishonesty in a chemistry classroom laboratory

NASA Astrophysics Data System (ADS)

Del Carlo, Dawn Irene

Academic dishonesty has been an important issue in the classroom for as long as the classroom has been in use. Most reports pertain to exams, homework, and plagiarism of term papers but, one area that has not been studied extensively is that of the classroom laboratory. My work focuses on three guiding questions: (1) What are students' perceptions toward academic dishonesty in a laboratory based class? (2) What distinction if any do students make between this type of academic dishonesty compared to dishonesty that may occur in a research laboratory? (3) How if at all do these perceptions change with age and/or research experience? Four major assertions come from this work. The first is that students do not think that what they do in the classroom laboratory is science and consequently do not treat the classroom laboratory differently than any other academic class. Additionally, they make a clear distinction between what happens in a class lab and what happens in a research or industrial lab. Consequently, students perceive there to be a significant difference in dishonesty between those two settings. Finally, this distinction is not as pronounced in graduate students and is seen as an element of maturity. In the process of determining the above assertions, students perceptions on the nature of science were revealed and are also discussed. These beliefs have direct relevance to students' perceptions of dishonesty in both lab atmospheres.

Comparison on the calibrations of hydrometers for liquids density determination between SIM laboratories

NASA Astrophysics Data System (ADS)

Morales, Abed; Quiroga, Aldo; Daued, Arturo; Cantero, Diana; Sequeira, Francisco; Castro, Luis Carlos; Becerra, Luis Omar; Salazar, Manuel; Vega, Maria

2017-01-01

A supplementary comparison was made between SIM laboratories concerning the calibration of four hydrometers within the range of 600 kg/m3 to 2000 kg/m3. The main objectives of the comparison were to evaluate the degree of equivalences SIM NMIs in the calibration of hydrometers of high accuracy. The participant NMIs were: CENAM, IBMETRO, INEN, INDECOPI, INM, INTN and LACOMET. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Final report: survey and removal of radioactive surface contamination at environmental restoration sites, Sandia National Laboratories/New Mexico. Volume 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lambert, K.A.; Mitchell, M.M.; Jean, D.

1997-09-01

This report contains the Appendices A-L including Voluntary Corrective Measure Plans, Waste Management Plans, Task-Specific Health and Safety Plan, Analytical Laboratory Procedures, Soil Sample Results, In-Situ Gamma Spectroscopy Results, Radionuclide Activity Summary, TCLP Soil Sample Results, Waste Characterization Memoranda, Waste Drum Inventory Data, Radiological Risk Assessment, and Summary of Site-Specific Recommendations.

Onto-Agents-Enabling Intelligent Agents on the Web

DTIC Science & Technology

2005-05-01

AIR FORCE RESEARCH LABORATORY INFORMATION DIRECTORATE ROME RESEARCH SITE ROME, NEW YORK STINFO FINAL REPORT This report has been reviewed...by the Air Force Research Laboratory, Information Directorate, Public Affairs Office (IFOIPA) and is releasable to the National Technical... Information Service (NTIS). At NTIS it will be releasable to the general public, including foreign nations. AFRL-IF-RS-TR-2005-178 has been reviewed

The Development of a Project for Educable Mentally Retarded Children to Receive Vocational Training in Food Service. Final Report.

ERIC Educational Resources Information Center

Steffenberg, Mary L.

A Food Service Laboratory Project was initiated at a junior high school for the training, participation, and observation of educable mentally retarded (EMR) students. Thirty EMRs participated in the vocational training program, the academic portion of which was work-oriented and closely related to the work in the Food Service Laboratory. Students,…

Helicopter Dynamic Performance Program. Volume 2. User’s Manual

DTIC Science & Technology

1980-07-01

Technologies Corporation Stratford, Connecticut 06602 July 1980 Final Report / • ., . Approved for public release; I distribution unlimited. ; A - Prepared...for : APPLIED TECHNOLOGY LABORATORY U. S. ARMY RESEARCH AND TECHNOLOGY LABORATORIES (AVRADCOM) Fort Eustis, Va. 23604 80 8 27 D APPLIED TECHNOLOGY ... Technology Division. Technic31 review of this report was also pro- vided by Messrs. W_ A. Pleasants of Design Integration and Analysis Technical Area

Meeting the Curriculum Needs for Different Career Paths in Laboratory Medicine

PubMed Central

Smith, Brian R.

2008-01-01

There are a number of career paths in Laboratory Medicine and several clinical practice models for the discipline. This article summarizes the state of current training at the medical student and residency/post-graduate levels, emphasizing practice in the U.S., and the challenges of education in the discipline to meet the needs of diverse career paths. Data regarding effectiveness of current pedagogical Approaches are discussed along with a brief review of evolving didactic methodologies. The recently published curriculum in Laboratory Medicine (Clinical Pathology) by the Academy of Clinical Laboratory Physicians and Scientists is reviewed, including its major emphases and the importance of competency assessment. Finally, the future of Laboratory Medicine and Pathology and the need to train for that future is expanded upon. PMID:18410745

The association between restorative pre-clinical activities and musculoskeletal disorders.

PubMed

Corrocher, P A; Presoto, C D; Campos, J A D B; Garcia, P P N S

2014-08-01

To evaluate the risk of development of musculoskeletal disorders in the upper limbs of undergraduate dentistry students during the execution of pre-clinical laboratory activities based on gender, type of dental procedure and area of the mouth under treatment. Male and female undergraduate students in the second year of the Araraquara Dental School, UNESP, were enrolled in this study. Digital photographs were obtained whilst the subjects performed laboratory activities. The working postures adopted by each student were evaluated using the Rapid Upper Limb Assessment (RULA). The photos were analysed by a calibrated researcher (k = 0.89), and a final risk score was attributed to each analysed procedure (n = 354). Descriptive statistical analyses were performed, and the associations of interest were analysed by the chi-square test (P = 0.05). During most of the laboratory procedures performed, the risk of developing musculoskeletal disorders was high (64.7%; - IC95% : 59.7-69.7%), with no significant association between the RULA final score and gender (χ(2)  = 1.100; P = 0.577), type of dental procedure (χ(2)  = 5.447, P = 0.244) and mouth area treated (χ(2) =4.150; P = 0.126). The risk of developing musculoskeletal disorders was high in undergraduate dentistry students; this risk was not related to gender, type of dental procedure and region of the mouth being treated. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

A Study on the Effects of Sympathetic Skin Response Parameters in Diagnosis of Fibromyalgia Using Artificial Neural Networks.

PubMed

Ozkan, Ozhan; Yildiz, Murat; Arslan, Evren; Yildiz, Sedat; Bilgin, Suleyman; Akkus, Selami; Koyuncuoglu, Hasan R; Koklukaya, Etem

2016-03-01

Fibromyalgia syndrome (FMS), usually observed commonly in females over age 30, is a rheumatic disease accompanied by extensive chronic pain. In the diagnosis of the disease non-objective psychological tests and physiological tests and laboratory test results are evaluated and clinical experiences stand out. However, these tests are insufficient in differentiating FMS with similar diseases that demonstrate symptoms of extensive pain. Thus, objective tests that would help the diagnosis are needed. This study analyzes the effect of sympathetic skin response (SSR) parameters on the auxiliary tests used in FMS diagnosis, the laboratory tests and physiological tests. The study was conducted in Suleyman Demirel University, Faculty of Medicine, Physical Medicine and Rehabilitation Clinic in Turkey with 60 patients diagnosed with FMS for the first time and a control group of 30 healthy individuals. In the study all participants underwent laboratory tests (blood tests), certain physiological tests (pulsation, skin temperature, respiration) and SSR measurements. The test data and SSR parameters obtained were classified using artificial neural network (ANN). Finally, in the ANN framework, where only laboratory and physiological test results were used as input, a simulation result of 96.51 % was obtained, which demonstrated diagnostic accuracy. This data, with the addition of SSR parameter values obtained increased to 97.67 %. This result including SSR parameters - meaning a higher diagnostic accuracy - demonstrated that SSR could be a new auxillary diagnostic method that could be used in the diagnosis of FMS.

Tank 241-T-204, core 188 analytical results for the final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nuzum, J.L.

TANK 241-T-204, CORE 188, ANALYTICAL RESULTS FOR THE FINAL REPORT. This document is the final laboratory report for Tank 241 -T-204. Push mode core segments were removed from Riser 3 between March 27, 1997, and April 11, 1997. Segments were received and extruded at 222-8 Laboratory. Analyses were performed in accordance with Tank 241-T-204 Push Mode Core Sampling and analysis Plan (TRAP) (Winkleman, 1997), Letter of instruction for Core Sample Analysis of Tanks 241-T-201, 241- T-202, 241-T-203, and 241-T-204 (LAY) (Bell, 1997), and Safety Screening Data Qual@ Objective (DO) ODukelow, et al., 1995). None of the subsamples submitted for totalmore » alpha activity (AT) or differential scanning calorimetry (DC) analyses exceeded the notification limits stated in DO. The statistical results of the 95% confidence interval on the mean calculations are provided by the Tank Waste Remediation Systems Technical Basis Group and are not considered in this report.« less

Use of maxillofacial laboratory materials to construct a tissue-equivalent head phantom with removable titanium implantable devices for use in verification of the dose of intensity-modulated radiotherapy.

PubMed

Morris, K

2017-06-01

The dose of radiotherapy is often verified by measuring the dose of radiation at specific points within a phantom. The presence of high-density implant materials such as titanium, however, may cause complications both during calculation and delivery of the dose. Numerous studies have reported photon/electron backscatter and alteration of the dose by high-density implants, but we know of no evidence of a dosimetry phantom that incorporates high density implants or fixtures. The aim of the study was to design and manufacture a tissue-equivalent head phantom for use in verification of the dose in radiotherapy using a combination of traditional laboratory materials and techniques and 3-dimensional technology that can incorporate titanium maxillofacial devices. Digital designs were used together with Mimics® 18.0 (Materialise NV) and FreeForm® software. DICOM data were downloaded and manipulated into the final pieces of the phantom mould. Three-dimensional digital objects were converted into STL files and exported for additional stereolithography. Phantoms were constructed in four stages: material testing and selection, design of a 3-dimensional mould, manufacture of implants, and final fabrication of the phantom using traditional laboratory techniques. Three tissue-equivalent materials were found and used to successfully manufacture a suitable phantom with interchangeable sections that contained three versions of titanium maxillofacial implants. Maxillofacial and other materials can be used to successfully construct a head phantom with interchangeable titanium implant sections for use in verification of doses of radiotherapy. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

Ripeness sensor development. Final report of a Phase 2 study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stroshine, R.

This is a final report for the Phase II study entitled ``Ripeness Sensor Development.`` The overall objective of the study was the development of a prototype device capable of testing whole fruits for sugar content. Although ripeness and sugar content are not synonymous, they are closely related. Furthermore, the consumer`s acceptance of or preference for fruits is strongly influenced by sugar content. Therefore, the device was called a ripeness sensor. The principle behind the measurement is proton magnetic resonance ({sup 1}H-MR). For several decades, chemists, pharmacists and other scientists have been using {sup 1}H-MR to investigate chemical structure and composition.more » More recently, the technique has been used in laboratories of the food industry for quality control. This effort represents one of the first attempts to adapt {sup 1}H-MR to use in a commercial facility. 28 refs., 36 figs., 7 tabs.« less

Inter-laboratory exercise on antibiotic drugs analysis in aqueous samples.

PubMed

Roig, B; Brogat, M; Mompelat, S; Leveque, J; Cadiere, A; Thomas, O

2012-08-30

An inter-laboratory exercise was organized under the PHARMAS EU project, by the Advanced School of Public Health (EHESP), in order to evaluate the performances of analytical methods for the measurement of antibiotics in waters (surface and tap). This is the first time such an exercise on antibiotics has been organized in Europe, using different kinds of analytical methods and devices. In this exercise thirteen laboratories from five countries (Canada, France, Italy, the Netherlands and Portugal) participated, and a total number of 78 samples were distributed. During the exercise, 2 testing samples (3 bottles of each) prepared from tap water and river water, respectively, spiked with antibiotics, were sent to participants and analyzed over a period of one month. A final number of 77 (98.7%) testing samples were considered. Depending on substances studied by each participant, 305 values in duplicate were collected, with the results for each sample being expressed as the target concentration. A statistical study was initiated using 611 results. The mean value, standard deviation, coefficient of variation, standard uncertainty of the mean, median, the minimum and maximum values of each series as well as the 95% confidence interval were obtained from each participant laboratory. In this exercise, 36 results (6% of accounted values) were outliers according to the distribution over the median (box plot). The outlier results were excluded. In order to establish the stability of testing samples in the course of the exercise, differences between variances obtained for every type of sample at different intervals were evaluated. The results showed no representative variations and it can be considered that all samples were stable during the exercise. The goals of this inter-laboratory study were to assess results variability when analysis is conducted by different laboratories, to evaluate the influence of different matrix samples, and to determine the rate at which participating laboratories successfully completed the tests initiated. Copyright © 2012 Elsevier B.V. All rights reserved.

Physiological response of invasive mussel Limnoperna fortunei (Dunker, 1857) (Bivalvia: Mytilidae) submitted to transport and experimental conditions.

PubMed

Cordeiro, N I S; Andrade, J T M; Montresor, L C; Luz, D M R; Araújo, J M; Martinez, C B; Pinheiro, J; Vidigal, T H D A

2017-03-01

Successful animal rearing under laboratory conditions for commercial processes or laboratory experiments is a complex chain that includes several stressors (e.g., sampling and transport) and incurs, as a consequence, the reduction of natural animal conditions, economic losses and inconsistent and unreliable biological results. Since the invasion of the bivalve Limnoperna fortunei (Dunker, 1857) in South America, several studies have been performed to help control and manage this fouling pest in industrial plants that use raw water. Relatively little attention has been given to the laboratory rearing procedure of L. fortunei, its condition when exposed to a stressor or its acclimation into laboratory conditions. Considering this issue, the aims of this study are to (i) investigate L. fortunei physiological responses when submitted to the depuration process and subsequent air transport (without water/dry condition) at two temperatures, based on glycogen concentrations, and (ii) monitor the glycogen concentrations in different groups when maintained for 28 days under laboratory conditions. Based on the obtained results, depuration did not affect either of the groups when they were submitted to approximately eight hours of transport. The variation in glycogen concentration among the specimens that were obtained from the field under depurated and non-depurated conditions was significant only in the first week of laboratory growth for the non-depurated group and in the second week for the depurated group. In addition, the tested temperature did not affect either of the groups that were submitted to transport. The glycogen concentrations were similar to those of the specimens that were obtained from the field in third week, which suggests that the specimens acclimated to laboratory conditions during this period of time. Thus, the results indicate that the air transport and acclimation time can be successfully incorporated into experimental studies of L. fortunei. Finally, the tolerance of L. fortunei specimens to the stressor tested herein can help us understand the invasive capacity of this mussel during the establishment process.

Laboratory Animal Workers' Attitudes and Perceptions Concerning Occupational Risk and Injury.

PubMed

Steelman, Eric D; Alexander, Jeffrey L

2016-01-01

Little is known regarding the risk perceptions and attitudes of laboratory animal care workers toward biologic safety. The purpose of this descriptive study was to assess the attitudes and perceptions of laboratory animal workers toward occupational and injury risk. Subscribers to the CompMed and TechLink listservs (n = 4808) were surveyed electronically, and 5.3% responded; data from 215 respondents were included in the final analysis. Primary variables of interest included AALAS certifications status, level of education, and responses to Likert-scale questions related to attitudes and perceptions of occupational risk and injury. Nonparametric (χ(2)) testing and measures of central tendency and dispersion were used to analyze and describe the data. According to 88.6% of respondents, biologic safety training is provided with information about zoonotic diseases of laboratory animals. Level of education was significantly related to perception of importance regarding wearing personal protective equipment. Participants indicated that appropriate support from coworkers and management staff is received, especially when performance and perception are hindered due to stress and fatigue. Laboratory animal staff are susceptible to injury and exposure to dangerous organisms and toxic substances. For this reason, to maximize safety, yearly biologic safety training should be provided, the importance of protective equipment adherence strengthened, and the culture of safety made a priority within the institution.

Clostridium botulinum and the clinical laboratorian: a detailed review of botulism, including biological warfare ramifications of botulinum toxin.

PubMed

Caya, James G; Agni, Rashmi; Miller, Joan E

2004-06-01

This review article is designed to thoroughly familiarize all health care professionals with the history, classification, epidemiology, clinical characteristics, differential diagnosis, diagnostic evaluation (including laboratory-based testing), treatment, and prognosis of botulism. It is especially targeted toward clinical laboratorians and includes a detailed enumeration of the important clinical laboratory contributions to the diagnosis, treatment, and monitoring of patients with botulism. Finally, the bioterrorism potential for botulism is discussed, with an emphasis on the clinical laboratory ramifications of this possibility. Included medical periodicals and textbooks accessioned from computerized and manual medical literature searches. More than 1000 medical works published from the 1800s through 2003 were retrieved and reviewed in this process. Pertinent data are presented in textual and tabular formats, the latter including 6 tables presenting detailed information regarding the clinical parameters, differential diagnosis, diagnostic studies, laboratory testing, and therapeutic approaches to botulism. Because botulism is such a rare disease, a keen awareness of its manifestations and prompt diagnosis are absolutely crucial for its successful treatment. The bioterrorism potential of botulism adds further urgency to the need for all health care professionals to be familiar with this disease, its proper evaluation, and timely treatment; the need for such urgency clearly includes the clinical laboratory.

Supplement analysis for continued operation of Lawrence Livermore National Laboratory and Sandia National Laboratories, Livermore. Volume 2: Comment response document

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1999-03-01

The US Department of Energy (DOE), prepared a draft Supplement Analysis (SA) for Continued Operation of Lawrence Livermore National Laboratory (LLNL) and Sandia National Laboratories, Livermore (SNL-L), in accordance with DOE`s requirements for implementation of the National Environmental Policy Act of 1969 (NEPA) (10 Code of Federal Regulations [CFR] Part 1021.314). It considers whether the Final Environmental Impact Statement and Environmental Impact Report for Continued Operation of Lawrence Livermore National Laboratory and Sandia National Laboratories, Livermore (1992 EIS/EIR) should be supplement3ed, whether a new environmental impact statement (EIS) should be prepared, or no further NEPA documentation is required. The SAmore » examines the current project and program plans and proposals for LLNL and SNL-L, operations to identify new or modified projects or operations or new information for the period from 1998 to 2002 that was not considered in the 1992 EIS/EIR. When such changes, modifications, and information are identified, they are examined to determine whether they could be considered substantial or significant in reference to the 1992 proposed action and the 1993 Record of Decision (ROD). DOE released the draft SA to the public to obtain stakeholder comments and to consider those comments in the preparation of the final SA. DOE distributed copies of the draft SA to those who were known to have an interest in LLNL or SNL-L activities in addition to those who requested a copy. In response to comments received, DOE prepared this Comment Response Document.« less

Prospecting of popcorn hybrids for resistance to fall armyworm.

PubMed

Crubelati-Mulati, N C S; Scapim, C A; Albuquerque, F A; Amaral Junior, A T; Vivas, M; Rodovalho, M A

2014-08-26

The fall armyworm, Spodoptera frugiperda, is the pest that causes the greatest economic losses for both common corn and popcorn crops, and the use of resistant plant genotypes is an important tool for integrated pest management. The goal of the present study was to evaluate the damage caused by S. frugiperda on single-cross popcorn hybrids under field conditions with natural infestation as well as to study the effect of 11 popcorn hybrids on the S. frugiperda life cycle under laboratory conditions. A completely randomized block design with 4 replicates was used for the field experiment, and a completely randomized design with 10 replicates was used for the laboratory experiment. In the field experiment, the damage caused by fall armyworm, grain yield, and popping expansion were quantified, and a diallel analysis was performed to select the best hybrids. For the laboratory experiment, caterpillars were obtained from laboratory cultures kept on an artificial diet and were fed with leaves from the 11 hybrids. Hybrids P7.0 x P9.4, P7.1 x P9.6, P7.2.0 x P9.3, P7.4.0 x P9.1 and P7.4.1 x P9.4 exhibited negative specific combining ability for injury by fall armyworm and positive specific combining ability for yield and popping expansion. In the laboratory experiment, the hybrids influenced the mean larval stage duration, mean larval mass, final larval mass, pupal stage duration, mean pupal mass, and adult longevity.

Prediction of vibrations induced by underground railway traffic in Beijing

NASA Astrophysics Data System (ADS)

Gupta, S.; Liu, W. F.; Degrande, G.; Lombaert, G.; Liu, W. N.

2008-02-01

This paper examines the problem of subway induced vibrations on line 4 of Beijing metro, which is currently under construction and is planned to pass in close proximity of the Physics Laboratory of Beijing University. The laboratory has a lot of equipment that is very sensitive to traffic induced vibrations and future operation of metro line 4 is a matter of concern. Hence, it is important to study the influence of subway induced vibrations inside the laboratory and to propose a viable solution to mitigate the vibrations. In this paper, the tunnel north of Chengfulu station is modelled using a coupled periodic FE-BE model and the free-field response due to moving trains is predicted. In addition, vibration measurements have been performed on the site of the Physics Laboratory to estimate the existing vibration levels due to road traffic. The predicted and measured vibrations are superimposed to assess the vibrations due to the combined effect of road and railway traffic in the vicinity of the Physics Laboratory. Apart from the numerical investigations, vibration measurements have also been performed on a similar site at line 1 of Beijing metro to substantiate the estimated results on metro line 4. Finally, it is studied how the vibrations can be controlled using a floating slab track, which is widely used as an effective measure of vibration isolation in tunnels. The efficiency of a 7.9 Hz floating slab track as a vibration countermeasure is assessed in this paper. This study demonstrates the applicability of the numerical model for the relevant assessment of subway induced vibrations and its use to study the performance of different track structures in the tunnel.

[Analytical quality in biological monitoring of workers exposed to chemicals: experience of the Prevention and Safety at the Workplace Service in Modena].

PubMed

Alpaca, R I Paredes; Migliore, A; Di Rico, R; Canali, Claudia; Rota, Cristina; Trenti, T; Cariani, Elisabetta

2010-01-01

The quality of laboratory data is one of the main factors in guaranteeing efficacy of biological monitoring. To analyze the quality of laboratory data used for biological monitoring of exposed workers. A survey involving 18 companies employing 945 workers in the area of Modena, Italy, was carried out in 2008. Most of the 9 private laboratories receiving biological samples did not perform directly part or all of the laboratory assessments requested, but this was not indicated in the final report. Major problems were observed in the application of internal quality control, and only one laboratory participated in external quality assessment for blood lead measurements. Our results raise major concerns on the traceability and reliability of laboratory assessments performed for biomonitoring of exposed workers. Systematic evaluation of the quality of analytical data would be highly recommendable.

Mercer County Community College Workplace Skills Project. Grant Period March 1, 1991-August 31, 1992. Final Evaluation.

ERIC Educational Resources Information Center

Mercer County Community Coll., Trenton, NJ.

This final report of an 18-month workplace literacy project (a partnership of Mercer County Community College, a large automobile components parts manufacturer, a hospital, a physics laboratory, and a chemical plant) contains the following: (1) and introduction; (2) a performance report on nine goals of the program; (3) a schedule of…

Corona from Ice, Thunderstorm Electrification and Lightning Suppression.

DTIC Science & Technology

1980-11-01

rates of droplets highly charged by interaction with corona streamers. Laboratory and theoretical studies have been performed in an effort to explore in...CORONA FROM ICE, THUNDERSTORM ELECTRIFICATION Final AND LIGHTNING SUPPRESSION 1 Sep 77 to 31 Aug 80 6. Performing Org. Report Number 7. Author(s) 8...Contract or Grant Number J. Latham AFOSR-77-3429 O"o 9. Performing Organization Name and Address 10. Program Element, Project, Task Physics Department

Hand controller study of force and control mode

NASA Technical Reports Server (NTRS)

Morris, A. Terry

1992-01-01

The objectives are to compare and evaluate the utility and effectiveness of various input control devices, e.g., hand controllers, with respect to the relative importance of force and operation control mode (rate or position) for Space Station Freedom (SSF) related tasks. The topics are presented in viewgraph form and include the: Intelligent Research Systems Lab (ISRL) experimental design; Telerobotic Systems Research Laboratory (TSRL) final experimental design; and factor analysis summary of results.

Electron-Beam Vapor Deposition of Mold Inserts Final Report CRADA No. TSB-777-94

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shepp, T.; Feeley, T.

Lawrence Livermore National Laboratory and H.G.G. Laser Fare, Inc. studied the application of electron-beam vapor deposition technology to the production of mold inserts for use in an injection molding machine by Laser Fare. Laser Fare provided LLNL with the requirements of the mold inserts as well as sample inserts. LLNL replicated the mold insert(s) to Laser Fare for testing by Laser Fare.

Effectiveness of Podcasts Delivered on Mobile Devices as a Support for Student Learning During General Chemistry Laboratories

NASA Astrophysics Data System (ADS)

Powell, Cynthia B.; Mason, Diana S.

2013-04-01

Chemistry instructors in teaching laboratories provide expert modeling of techniques and cognitive processes and provide assistance to enrolled students that may be described as scaffolding interaction. Such student support is particularly essential in laboratories taught with an inquiry-based curriculum. In a teaching laboratory with a high instructor-to-student ratio, mobile devices can provide a platform for expert modeling and scaffolding during the laboratory sessions. This research study provides data collected on the effectiveness of podcasts delivered as needed in a first-semester general chemistry laboratory setting. Podcasts with audio and visual tracks covering essential laboratory techniques and central concepts that aid in experimental design or data processing were prepared and made available for students to access on an as-needed basis on iPhones® or iPod touches®. Research focused in three areas: the extent of podcast usage, the numbers and types of interactions between instructors and student laboratory teams, and student performance on graded assignments. Data analysis indicates that on average the podcast treatment laboratory teams accessed a podcast 2.86 times during the laboratory period during each week that podcasts were available. Comparison of interaction data for the lecture treatment laboratory teams and podcast treatment laboratory teams reveals that scaffolding interactions with instructors were statistically significantly fewer for teams that had podcast access rather than a pre-laboratory lecture. The implication of the results is that student laboratory teams were able to gather laboratory information more effectively when it was presented in an on-demand podcast format than in a pre-laboratory lecture format. Finally, statistical analysis of data on student performance on graded assignments indicates no significant differences between outcome measures for the treatment groups when compared as cohorts. The only statistically significant difference is between students who demonstrated a high level of class participation in the concurrent general chemistry lecture course; for this sub-group the students in the podcast treatment group earned a course average that was statistically significantly higher than those in the lecture treatment group.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, W.; Kan, A.T.; Fu, G.

Neutral organic contaminants commonly reside on the solid portion of soils and sediments. The extent of desorption from these solids determines the fate, reactivity, and toxicity. Numerous researchers have observed that, after an initial exposure of a few days, desorption takes place in two phases, namely, an initial rapid release followed by a long-term resistant phase. Resistant desorption has been highly unpredictable. In this research, the adsorption and desorption of chlorobenzenes, hexachlorobutadiene, and naphthalene have been studied using historically and freshly contaminated bayou sediments from Lake Charles, Louisiana, USA. After an initial release period, both laboratory-spiked and historically contaminated sedimentsmore » from Lake Charles, Louisiana, USA. After an initial release period, both laboratory-spiked and historically contaminated sediments exhibit similar desorption profiles. The simulations compare favorably with previous in situ measurements. All desorption results, both laboratory and field, could reasonably be interpreted using a single irreversible isotherm. Consequences of these results in terms of sediment quality criteria (SQC) are also discussed. Finally, an index of fractional irreversible adsorption is proposed and tested.« less

Laboratory and Space Plasma Studies

NASA Astrophysics Data System (ADS)

Hyman, Ellis

1996-08-01

The work performed by Science Applications International Corporation (SAIC), encompasses a wide range of topics in experimental, computational, and analytical laboratory and space plasma physics. The accomplishments described in this report have been in support of the programs of the Laser Plasma Branch (Code 6730) and other segments of the Plasma Physics Division at the Naval Research Laboratory (NRL) and cover the period 27 September 1993 to August 1, 1996. SAIC's efforts have been supported by sub-contracts or consulting agreements with Pulse Sciences, Inc., Clark Richardson, and Biskup Consulting Engineers, Pharos Technical Enterprises, Plex Corporation, Cornell University, Stevens Institute of Technology, the University of Connecticut, Plasma Materials and Technologies, Inc., and GaSonics International, Inc. In the following discussions section we will describe each of the topics investigated and the results obtained. Much of the research work has resulted in journal publications and NRL Memorandum Reports in which the investigation is described in detail. These reports are included as Appendices to this Final Report.

Thermally stable electrolytes for rechargeable lithium batteries, phase 2

NASA Technical Reports Server (NTRS)

Dominey, L. A.; Goldman, J. L.; Koch, V. R.

1989-01-01

During the second year of research under NASA SBIR Contract NAS7-967, Covalent Associates and NASA contract monitors at the Jet Propulsion Laboratory agreed to perform an evaluation of the three best electrolytes developed during Phase 2. Due to the extensive period of time required to collect meaningful cycling data, we realized the study would extend well beyond the original formal end of the Phase 2 program (August 31, 1988). The substitution of this effort in lieu of an earlier proposed 20-cell final deliverable is formally documented in Modification No. 1 of Contract NAS7-967 as task 7. This Addendum contains the results of the cycling studies performed at Covalent Associates. In addition, sealed ampoules of each of these three electrolytes were delivered to the Jet Propulsion Laboratory Electrochemical Power Group. Their concurrent evaluation in a different test vehicle has also been recently concluded and their results are also summarized herein.

Thermally stable electrolytes for rechargeable lithium batteries, phase 2

NASA Astrophysics Data System (ADS)

Dominey, L. A.; Goldman, J. L.; Koch, V. R.

1989-09-01

During the second year of research under NASA SBIR Contract NAS7-967, Covalent Associates and NASA contract monitors at the Jet Propulsion Laboratory agreed to perform an evaluation of the three best electrolytes developed during Phase 2. Due to the extensive period of time required to collect meaningful cycling data, we realized the study would extend well beyond the original formal end of the Phase 2 program (August 31, 1988). The substitution of this effort in lieu of an earlier proposed 20-cell final deliverable is formally documented in Modification No. 1 of Contract NAS7-967 as task 7. This Addendum contains the results of the cycling studies performed at Covalent Associates. In addition, sealed ampoules of each of these three electrolytes were delivered to the Jet Propulsion Laboratory Electrochemical Power Group. Their concurrent evaluation in a different test vehicle has also been recently concluded and their results are also summarized herein.

Visible light reduces C. elegans longevity.

PubMed

De Magalhaes Filho, C Daniel; Henriquez, Brian; Seah, Nicole E; Evans, Ronald M; Lapierre, Louis R; Dillin, Andrew

2018-03-02

The transparent nematode Caenorhabditis elegans can sense UV and blue-violet light to alter behavior. Because high-dose UV and blue-violet light are not a common feature outside of the laboratory setting, we asked what role, if any, could low-intensity visible light play in C. elegans physiology and longevity. Here, we show that C. elegans lifespan is inversely correlated to the time worms were exposed to visible light. While circadian control, lite-1 and tax-2 do not contribute to the lifespan reduction, we demonstrate that visible light creates photooxidative stress along with a general unfolded-protein response that decreases the lifespan. Finally, we find that long-lived mutants are more resistant to light stress, as well as wild-type worms supplemented pharmacologically with antioxidants. This study reveals that transparent nematodes are sensitive to visible light radiation and highlights the need to standardize methods for controlling the unrecognized biased effect of light during lifespan studies in laboratory conditions.

Efficiency in pathology laboratories: a survey of operations management in NHS bacteriology.

PubMed

Szczepura, A K

1991-01-01

In recent years pathology laboratory services in the U.K. have experienced large increases in demand. But the extent to which U.K. laboratories have introduced controls to limit unnecessary procedures within the laboratory was previously unclear. This paper presents the results of a survey of all 343 NHS bacteriology laboratories which records the extent to which such operations management controls are now in place. The survey shows large differences between laboratories. Quality controls over inputs, the use of screening tests as a culture substitute, the use of direct susceptibility testing, controls over routine antibiotic susceptibility testing, and controls over reporting of results all vary widely. The survey also records the prevalence of hospital antibiotic policies, the extent to which laboratories produce antibiograms for user clinicians, the degree of computerisation in data handling, and the degree of automation in processing specimens. Finally, the survey uncovers a large variation between NHS labs in the percentage of bacteriology samples which prove positive and lead to antibiotic susceptibility tests being carried out.

Collaborative Systems Biology Projects for the Military Medical Community.

PubMed

Zalatoris, Jeffrey J; Scheerer, Julia B; Lebeda, Frank J

2017-09-01

This pilot study was conducted to examine, for the first time, the ongoing systems biology research and development projects within the laboratories and centers of the U.S. Army Medical Research and Materiel Command (USAMRMC). The analysis has provided an understanding of the breadth of systems biology activities, resources, and collaborations across all USAMRMC subordinate laboratories. The Systems Biology Collaboration Center at USAMRMC issued a survey regarding systems biology research projects to the eight U.S.-based USAMRMC laboratories and centers in August 2016. This survey included a data call worksheet to gather self-identified project and programmatic information. The general topics focused on the investigators and their projects, on the project's research areas, on omics and other large data types being collected and stored, on the analytical or computational tools being used, and on identifying intramural (i.e., USAMRMC) and extramural collaborations. Among seven of the eight laboratories, 62 unique systems biology studies were funded and active during the final quarter of fiscal year 2016. Of 29 preselected medical Research Task Areas, 20 were associated with these studies, some of which were applicable to two or more Research Task Areas. Overall, studies were categorized among six general types of objectives: biological mechanisms of disease, risk of/susceptibility to injury or disease, innate mechanisms of healing, diagnostic and prognostic biomarkers, and host/patient responses to vaccines, and therapeutic strategies including host responses to therapies. We identified eight types of omics studies and four types of study subjects. Studies were categorized on a scale of increasing complexity from single study subject/single omics technology studies (23/62) to studies integrating results across two study subject types and two or more omics technologies (13/62). Investigators at seven USAMRMC laboratories had collaborations with systems biology experts from 18 extramural organizations and three other USAMRMC laboratories. Collaborators from six USAMRMC laboratories and 58 extramural organizations were identified who provided additional research expertise to these systems biology studies. At the end of fiscal year 2016, USAMRMC laboratories self-reported 66 systems biology/computational biology studies (62 of which were unique) with 25 intramural and 81 extramural collaborators. Nearly two-thirds were led by or in collaboration with the U.S. Army Telemedicine and Advanced Technology Research Center/Department of Defense Biotechnology High-Performance Computing Software Applications Institute and U.S. Army Center for Environmental Health Research. The most common study objective addressed biological mechanisms of disease. The most common types of Research Task Areas addressed infectious diseases (viral and bacterial) and chemical agents (environmental toxicant exposures, and traditional and emerging chemical threats). More than 40% of the studies (27/62) involved collaborations between the reporting USAMRMC laboratory and one other organization. Nearly half of the studies (30/62) involved collaborations between the reporting USAMRMC laboratory and at least two other organizations. These survey results indicate that USAMRMC laboratories are compliant with data-centric policy and guidance documents whose goals are to prevent redundancy and promote collaborations by sharing data and leveraging capabilities. These results also serve as a foundation to make recommendations for future systems biology research efforts. Reprint & Copyright © 2017 Association of Military Surgeons of the U.S.

The Double R Theory of Language Comprehension

DTIC Science & Technology

2004-02-01

AFRL-HE-AZ-TR- 2003 - 0110 Approved for public release; distribution is unlimited. AIR FORCE MATERIEL COMMAND AIR FORCE RESEARCH LABORATORY Human...REPORT TYPE Final 3. DATES COVERED (From - To) March 2003 to February 2004 5a. CONTRACT NUMBER F41624-97-D-5000 5b. GRANT NUMBER 4. TITLE...Laboratory Human Effectiveness Directorate Warfighter Training Research Division 6030 South Kent Street Mesa AZ 85212-6061 AFRL-HE-AZ-TR- 2003

Radioactive wastes in institutions of biological research (in French)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kirchmann, R.

1973-01-01

The different radioelements used in the Belgian biological research laboratories and the activities used are indicated. The types of utilization of / sup 3/H, /sup 14/C, /sup 32/P, /sup 125/I, /sup 131/I, /sup 85/Sr, and /sup 226/ Ra and the handling procedures of contaminated wastes of these radionuclides are described. Finally, the release in situ'' was estimated for all the laboratories that were investigated. (auth)

Laboratory Evaluation of Light Obscuration Particle Counters used to Establish use Limits for Aviation Fuel

DTIC Science & Technology

2015-12-01

markings are indicated, follow agency authorization procedures , e.g. RD/FRD, PROPIN, ITAR, etc. Include copyright information. 13. SUPPLEMENTARY...Contamination in Distillate Fuels (Visual Inspection Procedures ), as a final check of fuel to ensure aviation fuel is clear and bright before flight...Laboratories at the Detroit Arsenal. The online procedure for evaluating the light obscuration particle counters was modified from the concepts found

Preparing to Respond: Joint Trauma Training Center and USAF Nursing Warskills Simulation Laboratory

DTIC Science & Technology

2003-06-01

and disability assessments. The timed tasks included time to oxy- gen administration, auscultation , pneumothorax rec- ognition and decompression...helicopter landing played while the nurse was trying to auscultate lung sounds. Finally, the laboratory was equipped with microphones and recording...are unable to auscultate a blood pressure. The following ECG strip was obtained. The immediate action is to A. Immerse the airman into an ice slurry to

Friction Mapping as a Tool for Measuring the Elastohydrodynamic Contact Running-in Process

DTIC Science & Technology

2015-10-01

ARL-TR-7501 ● OCT 2015 US Army Research Laboratory Friction Mapping as a Tool for Measuring the Elastohydrodynamic Contact...Research Laboratory Friction Mapping as a Tool for Measuring the Elastohydrodynamic Contact Running-in Process by Stephen Berkebile Vehicle...YYYY) October 2015 2. REPORT TYPE Final 3. DATES COVERED (From - To) 1 January–30 June 2015 4. TITLE AND SUBTITLE Friction Mapping as a Tool for

An Action Resarch Proposal: Identifying and Addressing Problems Related to RACC's Writing Laboratory. Title III Curriculum Enrichment Activity: Faculty Development Project. Final Report.

ERIC Educational Resources Information Center

Horner, Annette; Jacobson, Karen H.

An action research project was undertaken to understand how the Writing Laboratory at Reading Area Community College (RACC) defines and accomplishes its work, what faculty and students expect of the lab, and how they make use of it. The investigation sought to foster discussion and reflection on the appropriate role and staffing of a college…

Use of a Commercially Available Flight Simulator during Aircrew Performance Testing.

DTIC Science & Technology

1991-11-01

Automiated Battery of Performance-based Tests, NAMRL 1354, Naval Aerospace Medical Research Laboratory, Pensacola, FL, 1990. 13. Human Performance...ability of an aircraft to remain airborne well beyond the limits of its human operator. This capacity for longer flights, coupled with a tendency for short...Measurement, Final Report, Air Force Human Resources Laboratory, Brooks AFB, TX, 1983. 5. Stein, E.S., Measurement of Pilot Performance: A Master Journeyman

Synthesis of 1,3-Dinitrohexahydropyrimidine via Ring Contraction of Ether-Linked Nitramines

DTIC Science & Technology

2016-07-01

ARL-TR-7706 ● JULY 2016 US Army Research Laboratory Synthesis of 1,3-Dinitrohexahydropyrimidine via Ring Contraction of Ether...JULY 2016 US Army Research Laboratory Synthesis of 1,3-Dinitrohexahydropyrimidine via Ring Contraction of Ether-Linked Nitramines by...YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM-YYYY) July 2016 2. REPORT TYPE Final 3. DATES COVERED (From - To) Fiscal Year 2013 4. TITLE

Final height in elite male artistic gymnasts.

PubMed

Georgopoulos, Neoklis A; Theodoropoulou, Anastasia; Roupas, Nikolaos D; Armeni, Anastasia K; Koukkou, Eftychia; Leglise, Michel; Markou, Kostas B

2012-01-01

Elite male artistic gymnasts (AG) are exposed to high levels of physical and psychological stress during adolescence and experience a significant late maturation in both linear growth and pubertal development. The aim of the present study was to determine the impact of intensive physical training on the adult final height in elite male AG. This study is unique in character, as all variables were measured on the field of competition. The study was prospective and longitudinal; however, the current analysis of data is cross-sectional. Data from 86 elite male AG were obtained during the gymnastics competitions of European and World Championships. Clinical evaluation included height and weight measurements, as well as assessment of pubic hair and genital development according to Tanner's stages of pubertal development. The laboratory investigation included determination of skeletal maturation. All athletes completed a questionnaire that included questions on personal (onset and intensity of training, number of competitions per year) and family data (paternal and maternal heights). Male AG were below the 50th percentile for both final height and weight. Elite male AG had final height standard deviation score (SDS) lower than their genetic predisposition. Final height SDS was correlated positively with target height SDS (r = 0.430, p < 0.001) and weight SDS (r = 0.477, p < 0.001) and negatively to the intensity of training (r = -0.252, p = 0.022). The main factors influencing final height, by multiple regression analysis were weight SDS (p < 0.001) and target height SDS (p = 0.003). In elite maleAG, final height falls short of genetic predisposition, still well within normal limits. Considering medical and psychological risks in general, and based on the results of this research project, the International Federation of Gymnastics has increased the age limit for participants in international gymnastics competitions by 1 year.

Overview of the NASA space radiation laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

La Tessa, Chiara; Sivertz, Michael; Chiang, I-Hung

The NASA Space Radiation Laboratory (NSRL) is a multidisciplinary center for space radiation research funded by NASA and located at the Brookhaven National Laboratory (BNL), Upton NY. Operational since 2003, the scope of NSRL is to provide ion beams in support of the NASA Humans in Space program in radiobiology, physics and engineering to measure the risk and ameliorate the effect of radiation in space. Recently, it has also been recognized as the only facility in the U.S. currently capable of contributing to heavy ion radiotherapy research. Finally, this work contains a general overview of NSRL structure, capabilities and operation.

Overview of the NASA space radiation laboratory

DOE PAGES

La Tessa, Chiara; Sivertz, Michael; Chiang, I-Hung; ...

2016-11-11

The NASA Space Radiation Laboratory (NSRL) is a multidisciplinary center for space radiation research funded by NASA and located at the Brookhaven National Laboratory (BNL), Upton NY. Operational since 2003, the scope of NSRL is to provide ion beams in support of the NASA Humans in Space program in radiobiology, physics and engineering to measure the risk and ameliorate the effect of radiation in space. Recently, it has also been recognized as the only facility in the U.S. currently capable of contributing to heavy ion radiotherapy research. Finally, this work contains a general overview of NSRL structure, capabilities and operation.

Consequences of keeping Mytilus in the laboratory as assessed by different cellular condition indices

NASA Astrophysics Data System (ADS)

Cajaraville, M. P.; Díez, G.; Marigómez, I. A.; Angulo, E.

1991-12-01

Mytilus galloprovincialis Lmk. were maintained in the laboratory for three months in a semicontinuous water flow system. Animals were fed a commercial filter-feeder food and sampled after 0, 21, 35, 49, 77, and 91 days. In order to establish whether laboratory conditions and the food used were deleterious to mussels, their health status was assessed by quantifying different histological parameters of the digestive gland tissue. It was concluded that mussels kept for more than 35 days under the described laboratory conditions showed signs of stress presumably caused by the reproductive state of the mussels investigated. The food used and the nutrition-related health status of the animals were adequate, as shown by transmission electron microscopical studies after the 91-day maintenance period. A stress response was also evoked by a 10-day starvation period, which was reflected by an increased proportion of type I and type IV digestive tubules, and a reduced “Mean Epithelial Thickness” (MET). Finally, the results demonstrate the sensitivity of quantitative histological diagnosis in comparison to subjective tubule grading procedures in the assessment of the degree of stress experienced by mussels.

The PPPL - Trenton Partnership: Past, Present, Future

NASA Astrophysics Data System (ADS)

Post-Zwicker, Andrew; Ritter, Christine; Morgan, James; Dejesus, Chris; Guilbert, Nick

2004-11-01

PPPL has an ongoing partnership with the Trenton, NJ public schools that leverages the unique resources of the laboratory in order to improve science education. The district is designated as an Abbott school district, one of 30 in NJ that are urban and poorer than the average. During the past year, PPPL has focused its efforts at the middle school level. A new science laboratory with an emphasis on energy and environmental studies is under construction and will open in 2005. PPPL is acting as a consultant on the design and will then provide scientific training for teachers. A middle school laboratory is a fertile starting ground for systemic change since it has the potential to affect a very susceptible student population. Simultaneously, to address current students' attitudes and encourage them, PPPL hosts the newly created middle school Science Bowl, a single day competition mixing quiz questions and a fuel cell powered car race. Finally, plans are underway to provide enrichment programs for students at PPPL and elsewhere during the summer. PPPL has the resources, expertise, and experience in the area of teacher professional experience, educational programming, and laboratory design to be the perfect agent to facilitate this effort.

Linking Aerosol Optical Properties Between Laboratory, Field, and Model Studies

NASA Astrophysics Data System (ADS)

Murphy, S. M.; Pokhrel, R. P.; Foster, K. A.; Brown, H.; Liu, X.

2017-12-01

The optical properties of aerosol emissions from biomass burning have a significant impact on the Earth's radiative balance. Based on measurements made during the Fourth Fire Lab in Missoula Experiment, our group published a series of parameterizations that related optical properties (single scattering albedo and absorption due to brown carbon at multiple wavelengths) to the elemental to total carbon ratio of aerosols emitted from biomass burning. In this presentation, the ability of these parameterizations to simulate the optical properties of ambient aerosol is assessed using observations collected in 2017 from our mobile laboratory chasing wildfires in the Western United States. The ambient data includes measurements of multi-wavelength absorption, scattering, and extinction, size distribution, chemical composition, and volatility. In addition to testing the laboratory parameterizations, this combination of measurements allows us to assess the ability of core-shell Mie Theory to replicate observations and to assess the impact of brown carbon and mixing state on optical properties. Finally, both laboratory and ambient data are compared to the optical properties generated by a prominent climate model (Community Earth System Model (CESM) coupled with the Community Atmosphere Model (CAM 5)). The discrepancies between lab observations, ambient observations and model output will be discussed.

Performance testing of radiobioassay laboratories: In vivo measurements, Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

MacLellan, J.A.; Traub, R.J.; Olsen, P.C.

1990-04-01

A study of two rounds of in vivo laboratory performance testing was undertaken by Pacific Northwest Laboratory (PNL) to determine the appropriateness of the in vivo performance criteria of draft American National Standards Institute (ANSI) standard ANSI N13.3, Performance Criteria for Bioassay.'' The draft standard provides guidance to in vivo counting facilities regarding the sensitivity, precision, and accuracy of measurements for certain categories of commonly assayed radionuclides and critical regions of the body. This report concludes the testing program by presenting the results of the Round Two testing. Testing involved two types of measurements: chest counting for radionuclide detection inmore » the lung, and whole body counting for detection of uniformly distributed material. Each type of measurement was further divided into radionuclide categories as defined in the draft standard. The appropriateness of the draft standard criteria by measuring a laboratory's ability to attain them were judged by the results of both round One and Round Two testing. The testing determined that performance criteria are set at attainable levels, and the majority of in vivo monitoring facilities passed the criteria when complete results were submitted. 18 refs., 18 figs., 15 tabs.« less

Practical experience with graphical user interfaces and object-oriented design in the clinical laboratory.

PubMed

Wells, I G; Cartwright, R Y; Farnan, L P

1993-12-15

The computing strategy in our laboratories evolved from research in Artificial Intelligence, and is based on powerful software tools running on high performance desktop computers with a graphical user interface. This allows most tasks to be regarded as design problems rather than implementation projects, and both rapid prototyping and an object-oriented approach to be employed during the in-house development and enhancement of the laboratory information systems. The practical application of this strategy is discussed, with particular reference to the system designer, the laboratory user and the laboratory customer. Routine operation covers five departments, and the systems are stable, flexible and well accepted by the users. Client-server computing, currently undergoing final trials, is seen as the key to further development, and this approach to Pathology computing has considerable potential for the future.

Assessment of the Impact of a New Guanidine Suppressor In NGS on F/H Laboratory Analyses For DWPF and Saltstone MCU Transfers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bannochie, C. J.

2013-04-29

Implementation of the Next Generation Solvent (NGS) in the Modular Caustic-Side Solvent Extraction Unit (MCU) will now proceed with a new suppressor compound, 1,2,3-tris(3,7-dimethyloctyl)guanidine (TiDG), replacing the originally planned suppressor for NGS, 1,3-dicyclohexyl-2-(11-methyldodecyl) guanidine (DCiTG). The Savannah River National Laboratory (SRNL) was tasked with evaluating the potential impact to F/H Laboratory analyses supporting the Defense Waste Processing Facility (DWPF) Waste Acceptance Criteria (WAC) used to qualify transfers of MCU Strip Effluent (SE) into the facility and the Saltstone WAC used to qualify transfers of Tank 50 containing Decontaminated Salt Solution (DSS) from MCU into Saltstone. This assigned scope is coveredmore » by a Task Technical and Quality Assurance Plan (TTQAP). Previous impact evaluations were conducted when the DCiTG suppressor was planned for NGS and concluded that there was no impact to either the determination of MCU SE pH nor the analysis of Isopar® L carryover in the MCU SE and DSS streams. SRNL reported on this series of cross-check studies between the SRNL and F/H Laboratories. The change in suppressor from DCiTG to TiDG in the NGS should not impact the measurement of Isopar® L or pH in SE or DSS necessary to satisfy DWPF and Saltstone WAC (Tank 50) criteria, respectively. A statistical study of the low bias observed in Isopar® L measurements in both SRNL and F/H Laboratories may be necessary now that the final NGS composition is fixed in order to quantify the low bias so that a proper correction can be applied to measurements critical to the DWPF and Saltstone WACs. Depending upon the final DWPF WAC requirement put in place for SE pH, it could become necessary to implement an alternative ICP-AES measurement of boron. The current blended solvent system testing in SRNL should address any impacts to Isopar® L carryover into either the DSS or the SE. It is recommended that SRNL monitor the current blended solvent work underway with simulants in SRNL as well as any DWPF CPC testing done with the new SE stream to ascertain whether any need develops that could result in modification of any currently planned F/H Laboratory testing protocols.« less

Why crying does and sometimes does not seem to alleviate mood: a quasi-experimental study.

PubMed

Gračanin, Asmir; Vingerhoets, Ad J J M; Kardum, Igor; Zupčić, Marina; Šantek, Maja; Šimić, Mia

Whereas retrospective studies suggest that crying can be beneficial in terms of mood enhancement, results of quasi-experimental laboratory studies consistently demonstrate its negative effects on mood. The present study was specifically designed to evaluate a parsimonious explanation for this paradox by assessing mood after crying in a laboratory, both immediately and at follow up. Mood ratings of 28 objectively established criers and 32 non-criers were compared before and immediately after the exposure to an emotional movie, as well as 20 and 90 min later. As expected, immediately after the film, negative mood significantly increased in criers, while it did not change in non-criers. This mood deterioration was followed by a recovery that resulted in return to the baseline mood levels at the third measurement. Criers subsequently reported mood enhancements at the final measurement compared to the pre-film measurement. Crying frequency did not predict mood changes above those predicted by the presence of crying. The observed relation between crying and more long-term mood recovery reconciles seemingly contrasting earlier results and provides a simple and obvious explanation. After the initial deterioration of mood following crying that was observed in laboratory studies, it apparently takes some time for the mood, not just to recover, but also to become even less negative than before the emotional event, which corresponds to the results of retrospective studies.

Neutron star evolution and emission

NASA Astrophysics Data System (ADS)

Epstein, R. I.; Edwards, B. C.; Haines, T. J.

1997-01-01

This is the final report of a three-year, Laboratory Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). The authors investigated the evolution and radiation characteristics of individual neutron stars and stellar systems. The work concentrated on phenomena where new techniques and observations are dramatically enlarging the understanding of stellar phenomena. Part of this project was a study of x-ray and gamma-ray emission from neutron stars and other compact objects. This effort included calculating the thermal x-ray emission from young neutron stars, deriving the radio and gamma-ray emission from active pulsars and modeling intense gamma-ray bursts in distant galaxies. They also measured periodic optical and infrared fluctuations from rotating neutron stars and search for high-energy TeV gamma rays from discrete celestial sources.

KSC-2009-2180

NASA Image and Video Library

2009-03-19

CAPE CANAVERAL, Fla. – This close-up shows some of the components of the Materials Science Research Rack-1, or MSRR-1, which arrived at NASA's Kennedy Space Center in Florida for final flight preparations. The size of a large refrigerator, MSRR-1 is 6 feet high, 3.5 feet wide and 40 inches deep and weighs about 1 ton. MSRR-1 is the payload for the STS-128 mission targeted to launch in August. The rack will be installed in the Leonardo Multi-Purpose Logistics Module for transport to the International Space Station . After arriving at the station, the rack will be housed in the U.S. Destiny laboratory. MSRR-1 will allow for study of a variety of materials including metals, ceramics, semiconductor crystals and glasses onboard the orbiting laboratory. Photo credit: NASA/Jim Grossmann

Radiation reaction studies in an all-optical set-up: experimental limitations

NASA Astrophysics Data System (ADS)

Samarin, G. M.; Zepf, M.; Sarri, G.

2018-06-01

The recent development of ultra-high intensity laser facilities is finally opening up the possibility of studying high-field quantum electrodynamics in the laboratory. Arguably, one of the central phenomena in this area is that of quantum radiation reaction experienced by an ultra-relativistic electron beam as it propagates through the tight focus of a laser beam. In this paper, we discuss the major experimental challenges that are to be faced in order to extract meaningful and quantitative information from this class of experiments using existing and near-term laser facilities.

Pulse combustion engineering research laboratory for indirect heating applications (PERL-IH). Final report, October 1, 1989-June 30, 1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

Belles, F.E.

1993-01-01

Uncontrolled NOx emissions from a variety of pulse combustors were measured. The implementation of flue-gas recirculation to reduce NOx was studied. A flexible workstation for parametric testing was built and used to study the phasing between pressure and heat release, and effects of fuel/air mixing on performance. Exhaust-pipe heat transfer was analyzed. An acoustic model of pulse combustion was developed. Technical support was provided to manufacturers on noise, ignition and condensation. A computerized bibliographic database on pulse combustion was created.

Peripheral inflammation and cognitive aging.

PubMed

Lim, Alvin; Krajina, Katarina; Marsland, Anna L

2013-01-01

Evidence suggests that inflammation, an innate immune response facilitating recovery from injury and pathogenic invasion, is positively associated with age-related cognitive decline and may play a role in risk for dementia. Physiological pathways linking the peripheral immune and central nervous systems are outlined, and studies linking inflammation with neurocognitive function are overviewed. We also present recent studies from our laboratory showing that midlife inflammation is related to cognitive function and brain morphology. Finally, potential implications for treatment, future directions, and limitations are discussed. Copyright © 2013 S. Karger AG, Basel.

Angiography in gastrointestinal bleeding in children

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meyerovitz, M.F.; Fellows, K.E.

1984-10-01

Twenty-seven children aged 1 day to 16 years studied arteriographically for acute or chronic gastrointestinal bleeding were reviewed. Children with known esophageal varices and portal hypertension were excluded. Final diagnoses were made in 25 patients by means of surgery, endoscopy, biopsy, laboratory data, and clinical follow-up. Of these 25 cases, arteriography gave a correct diagnosis in 64% and was falsely negative in 36%. The common causes of bleeding in this study were gastric and duodenal ulcers, gastritis, vascular malformations, and typhlitis. Transcatheter therapy was attempted in six acute bleeders, with success in three (50%).

The student perspective of high school laboratory experiences

NASA Astrophysics Data System (ADS)

Lambert, R. Mitch

High school science laboratory experiences are an accepted teaching practice across the nation despite a lack of research evidence to support them. The purpose of this study was to examine the perspective of students---stakeholders often ignored---on these experiences. Insight into the students' perspective was explored progressively using a grounded theory methodology. Field observations of science classrooms led to an open-ended survey of high school science students, garnering 665 responses. Twelve student interviews then focused on the data and questions evolving from the survey. The student perspective on laboratory experiences revealed varied information based on individual experience. Concurrent analysis of the data revealed that although most students like (348/665) or sometimes like (270/665) these experiences, some consistent factors yielded negative experiences and prompted suggestions for improvement. The category of responses that emerged as the core idea focused on student understanding of the experience. Students desire to understand the why do, the how to, and the what it means of laboratory experiences. Lacking any one of these, the experience loses educational value for them. This single recurring theme crossed the boundaries of age, level in school, gender, and even the student view of lab experiences as positive or negative. This study suggests reflection on the current laboratory activities in which science teachers engage their students. Is the activity appropriate (as opposed to being merely a favorite), does it encourage learning, does it fit, does it operate at the appropriate level of inquiry, and finally what can science teachers do to integrate these activities into the classroom curriculum more effectively? Simply stated, what can teachers do so that students understand what to do, what's the point, and how that point fits into what they are learning outside the laboratory?

Beyond-laboratory-scale prediction for channeling flows through subsurface rock fractures with heterogeneous aperture distributions revealed by laboratory evaluation

NASA Astrophysics Data System (ADS)

Ishibashi, Takuya; Watanabe, Noriaki; Hirano, Nobuo; Okamoto, Atsushi; Tsuchiya, Noriyoshi

2015-01-01

The present study evaluates aperture distributions and fluid flow characteristics for variously sized laboratory-scale granite fractures under confining stress. As a significant result of the laboratory investigation, the contact area in fracture plane was found to be virtually independent of scale. By combining this characteristic with the self-affine fractal nature of fracture surfaces, a novel method for predicting fracture aperture distributions beyond laboratory scale is developed. Validity of this method is revealed through reproduction of the results of laboratory investigation and the maximum aperture-fracture length relations, which are reported in the literature, for natural fractures. The present study finally predicts conceivable scale dependencies of fluid flows through joints (fractures without shear displacement) and faults (fractures with shear displacement). Both joint and fault aperture distributions are characterized by a scale-independent contact area, a scale-dependent geometric mean, and a scale-independent geometric standard deviation of aperture. The contact areas for joints and faults are approximately 60% and 40%. Changes in the geometric means of joint and fault apertures (µm), em, joint and em, fault, with fracture length (m), l, are approximated by em, joint = 1 × 102 l0.1 and em, fault = 1 × 103 l0.7, whereas the geometric standard deviations of both joint and fault apertures are approximately 3. Fluid flows through both joints and faults are characterized by formations of preferential flow paths (i.e., channeling flows) with scale-independent flow areas of approximately 10%, whereas the joint and fault permeabilities (m2), kjoint and kfault, are scale dependent and are approximated as kjoint = 1 × 10-12 l0.2 and kfault = 1 × 10-8 l1.1.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abdelaziz, Omar; Shrestha, Som S.; Shen, Bo

The Oak Ridge National Laboratory (ORNL) High-Ambient-Temperature Evaluation Program for Low-Global Warming Potential (Low-GWP) Refrigerants aims to develop an understanding of the performance of low-GWP alternative refrigerants relative to hydrochlorofluorocarbon (HCFC) and hydrofluorocarbon (HFC) refrigerants in packaged or Rooftop Unit (RTU) air conditioners under high-ambient-temperature conditions. This final report describes the parties involved, the alternative refrigerants selection process, the test procedures, and the final results.

Multi-Body Dynamic Contact Analysis. Tool for Transmission Design SBIR Phase II Final Report

DTIC Science & Technology

2003-04-01

shapes and natural frequencies were computed in COSMIC NASTRAN, and were validated against the published experimental modal analysis [17]. • Using...COSMIC NASTRAN via modal superposition. • Results from the structural analysis (mode shapes or forced response) were converted into IDEAS universal...ARMY RESEARCH LABORATORY Multi-body Dynamic Contact Analysis Tool for Transmission Design SBIR Phase II Final Report by

Hematology and pathology devices; reclassification; restricted devices; OTC test sample collection systems for drugs of abuse testing. Food and Drug Administration, HHS. Final rule.

PubMed

2000-04-07

The Food and Drug Administration (FDA) is reclassifying over-the-counter (OTC) test sample collection systems for drugs of abuse testing from class III (premarket approval) into class I (general controls) and exempting them from premarket notification (510(k)) and current good manufacturing practice (CGMP) requirements. FDA is also designating OTC test sample collection systems for drugs of abuse testing as restricted devices under the Federal Food, Drug, and Cosmetic Act (the act) and establishing restrictions intended to assure consumers that: The underlying laboratory test(s) are accurate and reliable; the laboratory performing the test(s) has adequate expertise and competency; and the product has adequate labeling and methods of communicating test results to consumers. Finally, FDA is adding a conforming amendment to the existing classification regulation for specimen transport and storage containers to clarify that it does not apply to specimen transport and storage containers that are part of an OTC test sample collection system for the purpose of testing for the presence of drugs of abuse or their metabolites in a laboratory.

78 FR 74229 - Medicare Program; Revisions to Payment Policies Under the Physician Fee Schedule, Clinical...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-10

...This major final rule with comment period addresses changes to the physician fee schedule, clinical laboratory fee schedule, and other Medicare Part B payment policies to ensure that our payment systems are updated to reflect changes in medical practice and the relative value of services. This final rule with comment period also includes a discussion in the Supplementary Information regarding various programs. (See the Table of Contents for a listing of the specific issues addressed in the final rule with comment period.)

[Use of guinea pigs for assessing the efficacy of vaccines against Lassa fever].

PubMed

Firsova, I V; Shatokhina, I V; Borisevich, I V; Evseev, A A; Maksimov, V A; Pantiukhov, V B; Khmelev, A L

2003-01-01

The use of guinea pigs as a laboratory model was proven to be appropriate in investigating the vaccines developed against Lassa fever at the preclinical study stage. An adapted variant of Lassa virus was cultivated, which caused death of guinea pigs with respect for an agent's dose. Finally, it was shown to be possible to investigate the immunogenic and protective properties of the inactivated antigen of Lassa virus in experiments with guinea pigs.

Building America Case Study: Side-by-Side Testing of Water Heating Systems: Results from 2013-2014 Evaluation Final Report, Cocoa, FL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rothgeb, Stacey K; Colon, C.; Martin, E.

The Florida Solar Energy Center (FSEC) has completed a fourth year-long evaluation on residential hot water heating systems in a laboratory environment (east central Florida, hot-humid climate). This report contains a summary of research activities regarding the evaluation of two residential electric heat pump water heaters (HPWHs), a solar thermal system utilizing a polymer glazed absorber and a high efficiency natural gas system.

Building America Case Study: Side-by-Side Testing of Water Heating Systems: Results from the 2013–2014 Evaluation Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

C. Colon and E. Martin

The Florida Solar Energy Center (FSEC) has completed a fourth year-long evaluation on residential hot water heating systems in a laboratory environment (east central Florida, hot-humid climate). This report contains a summary of research activities regarding the evaluation of two residential electric heat pump water heaters (HPWHs), a solar thermal system utilizing a polymer glazed absorber and a high efficiency natural gas system.

Concurrent Multidisciplinary Preliminary Assessment of Space Systems (COMPASS) Final Report: Advanced Long-Life Lander Investigating the Venus Environment (ALIVE)

NASA Technical Reports Server (NTRS)

Oleson, Steven R.

2018-01-01

The COncurrent Multidisciplinary Preliminary Assessment of Space Systems (COMPASS) Team partnered with the Applied Research Laboratory to perform a NASA Innovative Advanced Concepts (NIAC) Program study to evaluate chemical based power systems for keeping a Venus lander alive (power and cooling) and functional for a period of days. The mission class targeted was either a Discovery ($500M) or New Frontiers ($750M to $780M) class mission.

Laboratory and Field Studies of the Acoustics of Multiphase Ocean Bottom Materials

DTIC Science & Technology

2011-09-30

data from this measurement campaign is shown in Figs. 1, 2, 3 and 4. The statistical nature of this data will be assesed and comparison to models... environmental regulations limiting sound levels in the water, even for this source, which is intended to replace SUS. We conducted an engineering...Finally, a full listing of all grant-related activities is shown in the Fiscal Year Publications section below. IMPACT /APPLICATIONS The Biot-based

Clinical evaluation of the FreeStyle Precision Pro system.

PubMed

Brazg, Ronald; Hughes, Kristen; Martin, Pamela; Coard, Julie; Toffaletti, John; McDonnell, Elizabeth; Taylor, Elizabeth; Farrell, Lausanne; Patel, Mona; Ward, Jeanne; Chen, Ting; Alva, Shridhara; Ng, Ronald

2013-06-05

A new version of international standard (ISO 15197) and CLSI Guideline (POCT12) with more stringent accuracy criteria are near publication. We evaluated the glucose test performance of the FreeStyle Precision Pro system, a new blood glucose monitoring system (BGMS) designed to enhance accuracy for point-of-care testing (POCT). Precision, interference and system accuracy with 503 blood samples from capillary, venous and arterial sources were evaluated in a multicenter study. Study results were analyzed and presented in accordance with the specifications and recommendations of the final draft ISO 15197 and the new POCT12. The FreeStyle Precision Pro system demonstrated acceptable precision (CV <5%), no interference across a hematocrit range of 15-65%, and, except for xylose, no interference from 24 of 25 potentially interfering substances. It also met all accuracy criteria specified in the final draft ISO 15197 and POCT12, with 97.3-98.9% of the individual results of various blood sample types agreeing within ±12 mg/dl of the laboratory analyzer values at glucose concentrations <100mg/dl and within ±12.5% of the laboratory analyzer values at glucose concentrations ≥100 mg/dl. The FreeStyle Precision Pro system met the tighter accuracy requirements, providing a means for enhancing accuracy for point-of-care blood glucose monitoring. Copyright © 2013 Elsevier B.V. All rights reserved.

Effects of mandatory screening labs in directing the disposition of the apparently healthy psychiatric patient in the emergency department.

PubMed

Kagel, Karyn E; Smith, Meghan; Latyshenko, Ilya V; Mitchell, Christopher; Kagel, Andrew

2017-01-01

To determine whether mandatory psychiatric admission laboratory tests yield results that change the disposition of a patient with primary psychiatric complaint from admission to a psychiatric service to admission to a medical service. This was a single center retrospective cohort chart review study approved by the facility Institutional Review Board in which we used a records database maintained by the emergency department's social workers to access the records of every patient that presented to our emergency department with a psychiatric chief complaint between the dates of December 1, 2011, and December 1, 2013. We focused on those that were admitted to either a psychiatric service or a medical service after a thorough evaluation by the department of social work and an emergency provider. We applied our inclusion and exclusion criteria and reviewed the results of the mandatory psychiatric laboratory tests (complete blood count, comprehensive metabolic panel, thyroid stimulating hormone, acetaminophen, aspirin, blood alcohol level, urinalysis, urine pregnancy test, urine drug screen) required for admission. Our independent variables were the compulsory psychiatric admission laboratory tests and our dependent variable was the admission to a medical service. Of 5,606 laboratory tests that were ordered and produced results for the 682 patients enrolled in our study, 51 results were considered clinically significant abnormal results, or results requiring treatment prior to psychiatric service admission, by the 2 reviewing emergency physicians. Only one of 682 psychiatric patients received a final disposition to a medical service based upon abnormal laboratory studies. That patient presented without any medical complaints but a chief complaint of "suicidal ideation," and was found to have diabetic ketoacidosis. Based on our data, the probability that an abnormal laboratory test will result in a change in disposition is 1/682=0.1% (95% CI: 0.0% to 0.9%). Patients presenting to the emergency department with a psychiatric chief complaint and no physical complaints, abnormal vital signs, or abnormal physical exam findings have less than 1% probability that an abnormal laboratory study will change their disposition from a psychiatric admission to a medical admission.

A highly sensitive and specific method for the screening detection of genetically modified organisms based on digital PCR without pretreatment

PubMed Central

Fu, Wei; Zhu, Pengyu; Wang, Chenguang; Huang, Kunlun; Du, Zhixin; Tian, Wenying; Wang, Qin; Wang, Huiyu; Xu, Wentao; Zhu, Shuifang

2015-01-01

Digital PCR has developed rapidly since it was first reported in the 1990s. It was recently reported that an improved method facilitated the detection of genetically modified organisms (GMOs). However, to use this improved method, the samples must be pretreated, which could introduce inaccuracy into the results. In our study, we explored a pretreatment-free digital PCR detection method for the screening for GMOs. We chose the CaMV35s promoter and the NOS terminator as the templates in our assay. To determine the specificity of our method, 9 events of GMOs were collected, including MON810, MON863, TC1507, MIR604, MIR162, GA21, T25, NK603 and Bt176. Moreover, the sensitivity, intra-laboratory and inter-laboratory reproducibility of our detection method were assessed. The results showed that the limit of detection of our method was 0.1%, which was lower than the labeling threshold level of the EU. The specificity and stability among the 9 events were consistent, respectively. The intra-laboratory and inter-laboratory reproducibility were both good. Finally, the perfect fitness for the detection of eight double-blind samples indicated the good practicability of our method. In conclusion, the method in our study would allow more sensitive, specific and stable screening detection of the GMO content of international trading products. PMID:26239916

A highly sensitive and specific method for the screening detection of genetically modified organisms based on digital PCR without pretreatment.

PubMed

Fu, Wei; Zhu, Pengyu; Wang, Chenguang; Huang, Kunlun; Du, Zhixin; Tian, Wenying; Wang, Qin; Wang, Huiyu; Xu, Wentao; Zhu, Shuifang

2015-08-04

Digital PCR has developed rapidly since it was first reported in the 1990 s. It was recently reported that an improved method facilitated the detection of genetically modified organisms (GMOs). However, to use this improved method, the samples must be pretreated, which could introduce inaccuracy into the results. In our study, we explored a pretreatment-free digital PCR detection method for the screening for GMOs. We chose the CaMV35s promoter and the NOS terminator as the templates in our assay. To determine the specificity of our method, 9 events of GMOs were collected, including MON810, MON863, TC1507, MIR604, MIR162, GA21, T25, NK603 and Bt176. Moreover, the sensitivity, intra-laboratory and inter-laboratory reproducibility of our detection method were assessed. The results showed that the limit of detection of our method was 0.1%, which was lower than the labeling threshold level of the EU. The specificity and stability among the 9 events were consistent, respectively. The intra-laboratory and inter-laboratory reproducibility were both good. Finally, the perfect fitness for the detection of eight double-blind samples indicated the good practicability of our method. In conclusion, the method in our study would allow more sensitive, specific and stable screening detection of the GMO content of international trading products.

Preanalytical management: serum vacuum tubes validation for routine clinical chemistry.

PubMed

Lima-Oliveira, Gabriel; Lippi, Giuseppe; Salvagno, Gian Luca; Montagnana, Martina; Picheth, Geraldo; Guidi, Gian Cesare

2012-01-01

The validation process is essential in accredited clinical laboratories. Aim of this study was to validate five kinds of serum vacuum tubes for routine clinical chemistry laboratory testing. Blood specimens from 100 volunteers in five different serum vacuum tubes (Tube I: VACUETTE, Tube II: LABOR IMPORT, Tube III: S-Monovette, Tube IV: SST and Tube V: SST II) were collected by a single, expert phlebotomist. The routine clinical chemistry tests were analyzed on cobas 6000 module. The significance of the differences between samples was assessed by paired Student's t-test after checking for normality. The level of statistical significance was set at P < 0.005. Finally, the biases from Tube I, Tube II, Tube III, Tube IV and Tube V were compared with the current desirable quality specifications for bias (B), derived from biological variation. Basically, our validation will permit the laboratory or hospital managers to select the brand's vacuum tubes validated according him/her technical or economical reasons, in order to perform the following laboratory tests: glucose, total cholesterol, high density lipoprotein-cholesterol, triglycerides, total protein, albumin, blood urea nitrogen, uric acid, alkaline phosphatise, aspartate aminotransferase, gamma-glutamyltransferase, lactate dehydrogenase, creatine kinase, total bilirubin, direct bilirubin, calcium, iron, sodium and potassium. On the contrary special attention will be required if the laboratory already performs creatinine, amylase, phosphate and magnesium determinations and the quality laboratory manager intend to change the serum tubes. We suggest that laboratory management should both standardize the procedures and frequently evaluate the quality of in vitro diagnostic devices.

Preanalytical management: serum vacuum tubes validation for routine clinical chemistry

PubMed Central

Lima-Oliveira, Gabriel; Lippi, Giuseppe; Salvagno, Gian Luca; Montagnana, Martina; Picheth, Geraldo; Guidi, Gian Cesare

2012-01-01

Introduction The validation process is essential in accredited clinical laboratories. Aim of this study was to validate five kinds of serum vacuum tubes for routine clinical chemistry laboratory testing. Materials and methods: Blood specimens from 100 volunteers in five diff erent serum vacuum tubes (Tube I: VACUETTE®, Tube II: LABOR IMPORT®, Tube III: S-Monovette®, Tube IV: SST® and Tube V: SST II®) were collected by a single, expert phlebotomist. The routine clinical chemistry tests were analyzed on cobas® 6000 module. The significance of the diff erences between samples was assessed by paired Student’s t-test after checking for normality. The level of statistical significance was set at P < 0.005. Finally, the biases from Tube I, Tube II, Tube III, Tube IV and Tube V were compared with the current desirable quality specifications for bias (B), derived from biological variation. Results and conclusions: Basically, our validation will permit the laboratory or hospital managers to select the brand’s vacuum tubes validated according him/her technical or economical reasons, in order to perform the following laboratory tests: glucose, total cholesterol, high density lipoprotein-cholesterol, triglycerides, total protein, albumin, blood urea nitrogen, uric acid, alkaline phosphatise, aspartate aminotransferase, gamma-glutamyltransferase, lactate dehydrogenase, creatine kinase, total bilirubin, direct bilirubin, calcium, iron, sodium and potassium. On the contrary special attention will be required if the laboratory already performs creatinine, amylase, phosphate and magnesium determinations and the quality laboratory manager intend to change the serum tubes. We suggest that laboratory management should both standardize the procedures and frequently evaluate the quality of in vitro diagnostic devices. PMID:22838184

Soil examination for a forensic trace evidence laboratory-Part 3: A proposed protocol for the effective triage and management of soil examinations.

PubMed

Woods, Brenda; Lennard, Chris; Kirkbride, K Paul; Robertson, James

2016-05-01

In the past, forensic soil examination was a routine aspect of forensic trace evidence examinations. The apparent need for soil examinations then went through a period of decline and with it the capability of many forensic laboratories to carry out soil examinations. In more recent years, interest in soil examinations has been renewed due-at least in part-to soil examinations contributing to some high profile investigations. However, much of this renewed interest has been in organisations with a primary interest in soil and geology rather than forensic science. We argue the need to reinstate soil examinations as a trace evidence sub-discipline within forensic science laboratories and present a pathway to support this aim. An examination procedure is proposed that includes: (i) appropriate sample collection and storage by qualified crime scene examiners; (ii) exclusionary soil examinations by trace evidence scientists within a forensic science laboratory; (iii) inclusionary soil examinations by trace evidence scientists within a forensic science laboratory; and (iv) higher-level examination of soils by specialist soil scientists and palynologists. Soil examinations conducted by trace evidence scientists will be facilitated if the examinations are conducted using the instrumentation routinely used by these examiners. Hence, the proposed examination protocol incorporates instrumentation in routine use in a forensic trace evidence laboratory. Finally, we report on an Australian soil scene variability study and a blind trial that demonstrate the utility of the proposed protocol for the effective triage and management of soil samples by forensic laboratories. Crown Copyright © 2016. Published by Elsevier Ireland Ltd. All rights reserved.

Do we really need in-situ bioassays?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Salazar, M.H.; Salazar, S.M.

1995-12-31

In-situ bioassays are needed to validate the results from laboratory testing and to understand biological interactions. Standard laboratory protocols provide reproducible test results, and the precision of those tests can be mathematically defined. Significant correlations between toxic substances and levels of response (bioaccumulation and bioeffects) have also been demonstrated with natural field populations and suggest that the laboratory results can accurately predict field responses. An equal number of studies have shown a lack of correlation between laboratory bioassay results and responses of natural field populations. The best way to validate laboratory results is with manipulative field testing; i.e., in-situ bioassaysmore » with caged organisms. Bioaccumulation in transplanted bivalves has probably been the most frequently used form of an in-situ bioassay. The authors have refined those methods to include synoptic measurements of bioaccumulation and growth. Growth provides an easily-measured bioeffects endpoint and a means of calibrating bioaccumulation. Emphasis has been on minimizing the size range of test animals, repetitive measurements of individuals and standardization of test protocols for a variety of applications. They are now attempting to standardize criteria for accepting and interpreting data in the same way that laboratory bioassays have been standardized. Others have developed methods for in-situ bioassays using eggs, larvae, unicellular organisms, crustaceans, benthic invertebrates, bivalves, and fish. In the final analysis, the in-situ approach could be considered as an exposure system where any clinical measurements are possible. The most powerful approach would be to use the same species in laboratory and field experiments with the same endpoints.« less

Rotational Spectroscopy of Reactive Species at the Center for Astrochemical Studies.

NASA Astrophysics Data System (ADS)

Lattanzi, Valerio; Spezzano, Silvia; Caselli, Paola

2017-06-01

The Center for Astrochemical Studies at the Max Planck Institute for Extraterrestrial Physics in Garching, is a recently established group which collects scientists with very diverse backgrounds. In the same group observers, theoreticians, chemists and molecular astrophysicists join their efforts with the ultimate goal of properly interpreting observations with the new generation telescopes and unveiling our astrochemical/physical heritage. Among these tasks, the gas-phase spectroscopic characterisation of molecular species of astrophysical relevance is one of the main goals of the laboratory sub-group. This talk will mainly focus on the first experiment built in our center, the CASAC (CAS Absorption Cell) spectrometer: this experiment has been optimised on the production and probe of small molecular ions and radicals. The main laboratory techniques along with the more prominent outcomes of recent studies will be presented. Finally, a brief update on the status of the other instruments available in our center will be given, including their planned upgrades.

Study on fracture identification of shale reservoir based on electrical imaging logging

NASA Astrophysics Data System (ADS)

Yu, Zhou; Lai, Fuqiang; Xu, Lei; Liu, Lin; Yu, Tong; Chen, Junyu; Zhu, Yuantong

2017-05-01

In recent years, shale gas exploration has made important development, access to a major breakthrough, in which the study of mud shale fractures is extremely important. The development of fractures has an important role in the development of gas reservoirs. Based on the core observation and the analysis of laboratory flakes and laboratory materials, this paper divides the lithology of the shale reservoirs of the XX well in Zhanhua Depression. Based on the response of the mudstone fractures in the logging curve, the fracture development and logging Response to the relationship between the conventional logging and electrical imaging logging to identify the fractures in the work, the final completion of the type of fractures in the area to determine and quantify the calculation of fractures. It is concluded that the fracture type of the study area is high and the microstructures are developed from the analysis of the XX wells in Zhanhua Depression. The shape of the fractures can be clearly seen by imaging logging technology to determine its type.

Study and design of cryogenic propellant acquisition systems. Volume 1: Design studies

NASA Technical Reports Server (NTRS)

Burge, G. W.; Blackmon, J. B.

1973-01-01

An in-depth study and selection of practical propellant surface tension acquisition system designs for two specific future cryogenic space vehicles, an advanced cryogenic space shuttle auxiliary propulsion system and an advanced space propulsion module is reported. A supporting laboratory scale experimental program was also conducted to provide design information critical to concept finalization and selection. Designs using localized pressure isolated surface tension screen devices were selected for each application and preliminary designs were generated. Based on these designs, large scale acquisition prototype hardware was designed and fabricated to be compatible with available NASA-MSFC feed system hardware.

Participation in a Year-Long CURE Embedded into Major Core Genetics and Cellular and Molecular Biology Laboratory Courses Results in Gains in Foundational Biological Concepts and Experimental Design Skills by Novice Undergraduate Researchers†

PubMed Central

Peteroy-Kelly, Marcy A.; Marcello, Matthew R.; Crispo, Erika; Buraei, Zafir; Strahs, Daniel; Isaacson, Marisa; Jaworski, Leslie; Lopatto, David; Zuzga, David

2017-01-01

This two-year study describes the assessment of student learning gains arising from participation in a year-long curriculum consisting of a classroom undergraduate research experience (CURE) embedded into second-year, major core Genetics and Cellular and Molecular Biology (CMB) laboratory courses. For the first course in our CURE, students used micro-array or RNAseq analyses to identify genes important for environmental stress responses by Saccharomyces cerevisiae. The students were tasked with creating overexpressing mutants of their genes and designing their own original experiments to investigate the functions of those genes using the overexpression and null mutants in the second CURE course. In order to evaluate student learning gains, we employed three validated concept inventories in a pretest/posttest format and compared gains on the posttest versus the pretest with student laboratory final grades. Our results demonstrated that there was a significant correlation between students earning lower grades in the Genetics laboratory for both years of this study and gains on the Genetics Concept Assessment (GCA). We also demonstrated a correlation between students earning lower grades in the Genetics laboratory and gains on the Introductory Molecular and Cell Biology Assessment (IMCA) for year 1 of the study. Students furthermore demonstrated significant gains in identifying the variable properties of experimental subjects when assessed using the Rubric for Experimental (RED) design tool. Results from the administration of the CURE survey support these findings. Our results suggest that a year-long CURE enables lower performing students to experience greater gains in their foundational skills for success in the STEM disciplines. PMID:28904646

Participation in a Year-Long CURE Embedded into Major Core Genetics and Cellular and Molecular Biology Laboratory Courses Results in Gains in Foundational Biological Concepts and Experimental Design Skills by Novice Undergraduate Researchers.

PubMed

Peteroy-Kelly, Marcy A; Marcello, Matthew R; Crispo, Erika; Buraei, Zafir; Strahs, Daniel; Isaacson, Marisa; Jaworski, Leslie; Lopatto, David; Zuzga, David

2017-01-01

This two-year study describes the assessment of student learning gains arising from participation in a year-long curriculum consisting of a classroom undergraduate research experience (CURE) embedded into second-year, major core Genetics and Cellular and Molecular Biology (CMB) laboratory courses. For the first course in our CURE, students used micro-array or RNAseq analyses to identify genes important for environmental stress responses by Saccharomyces cerevisiae . The students were tasked with creating overexpressing mutants of their genes and designing their own original experiments to investigate the functions of those genes using the overexpression and null mutants in the second CURE course. In order to evaluate student learning gains, we employed three validated concept inventories in a pretest/posttest format and compared gains on the posttest versus the pretest with student laboratory final grades. Our results demonstrated that there was a significant correlation between students earning lower grades in the Genetics laboratory for both years of this study and gains on the Genetics Concept Assessment (GCA). We also demonstrated a correlation between students earning lower grades in the Genetics laboratory and gains on the Introductory Molecular and Cell Biology Assessment (IMCA) for year 1 of the study. Students furthermore demonstrated significant gains in identifying the variable properties of experimental subjects when assessed using the Rubric for Experimental (RED) design tool. Results from the administration of the CURE survey support these findings. Our results suggest that a year-long CURE enables lower performing students to experience greater gains in their foundational skills for success in the STEM disciplines.

[Evidence-based practice in nursing curricula: the experience of nursing degree course of Reggio Emilia. A pilot study].

PubMed

Finotto, Stefano; Chiesi, Ivens; Mecugni, Daniela; Casali, Patrizia; Doro, Lucia Maria Grazia; Lusetti, Simona

2010-01-01

Given the lack of evidence in literature concerning the presence of Evidence-Based Practice (EBP) in nursing curricula, but considering its importance in order to educate future nurses to use critical thinking and to base their practice on scientific evidence, tutors and nursing teachers of the Nursing Degree Course of Reggio Emilia (Università degli Studi di Modena e Reggio Emilia), have decided to introduce a three-year laboratory of EBP. The purposes of this project are: to describe the three-year EBP laboratory of Nursing Degree, its objectives, its structure, its integration with practical training and nursing subjects and its students evaluation strategies; to get students verify the perception of the usefulness of the three-year EBP laboratory regarding the elaboration of the graduation thesis, the search for appropriatem answers for patients met during clinical trainings and the usefulness of the EBP process in view of the development of their professional career. The design of research of this pilot study is correlation-descriptive. It has been selected a sample of convenience consisting of 56 nurses graduated in the autumn session of the academic year 2007-2008. For data collection we have used an electronic questionnaire (Microsoft Word with closed fields) structured for the purpose. The laboratory has been effective in learning to use the database to search for evidences and to use the database to search for evidences related to nursing problems met in training placements. Finally, graduated nurses consider the EBP process an essential element of professional nursing luggage. Although the sample is restricted the results indicates the good educational choice made by our Nursing Degree Course of integrating the EBP Laboratory in the curriculum.

Self-administration of cocaine, cannabis and heroin in the human laboratory: benefits and pitfalls.

PubMed

Haney, Margaret

2009-01-01

The objective of this review is to describe self-administration procedures for modeling addiction to cocaine, cannabis and heroin in the human laboratory, the benefits and pitfalls of the approach, and the methodological issues unique to each drug. In addition, the predictive validity of the model for testing treatment medications will be addressed. The results show that all three drugs of abuse are reliably and robustly self-administered by non-treatment-seeking research volunteers. In terms of pharmacotherapies, cocaine use is extraordinarily difficult to disrupt either in the laboratory or in the clinic. A range of medications has been shown to significantly decrease cocaine's subjective effects and craving without decreasing either cocaine self-administration or cocaine abuse by patients. These negative data combined with recent positive findings with modafinil suggest that self-administration procedures are an important intermediary step between pre-clinical and clinical studies. In terms of cannabis, a recent study suggests that medications that improve sleep and mood during cannabis withdrawal decrease the resumption of marijuana self-administration in abstinent volunteers. Clinical data on patients seeking treatment for their marijuana use are needed to validate these laboratory findings. Finally, in contrast to cannabis or cocaine dependence, there are three efficacious Food and Drug Administration-approved medications to treat opioid dependence, all of which decrease both heroin self-administration and subjective effects in the human laboratory. In summary, self-administration procedures provide meaningful behavioral data in a small number of individuals. These studies contribute to our understanding of the variables maintaining cocaine, marijuana and heroin intake, and are important in guiding the development of more effective drug treatment programs.

Evaluation of cage designs and feeding regimes for honey bee (Hymenoptera: Apidae) laboratory experiments.

PubMed

Huang, Shao Kang; Csaki, Tamas; Doublet, Vincent; Dussaubat, Claudia; Evans, Jay D; Gajda, Anna M; Gregorc, Alex; Hamilton, Michele C; Kamler, Martin; Lecocq, Antoine; Muz, Mustafa N; Neumann, Peter; Ozkirim, Asli; Schiesser, Aygün; Sohr, Alex R; Tanner, Gina; Tozkar, Cansu Ozge; Williams, Geoffrey R; Wu, Lyman; Zheng, Huoqing; Chen, Yan Ping

2014-02-01

The aim of this study was to improve cage systems for maintaining adult honey bee (Apis mellifera L.) workers under in vitro laboratory conditions. To achieve this goal, we experimentally evaluated the impact of different cages, developed by scientists of the international research network COLOSS (Prevention of honey bee COlony LOSSes), on the physiology and survival of honey bees. We identified three cages that promoted good survival of honey bees. The bees from cages that exhibited greater survival had relatively lower titers of deformed wing virus, suggesting that deformed wing virus is a significant marker reflecting stress level and health status of the host. We also determined that a leak- and drip-proof feeder was an integral part of a cage system and a feeder modified from a 20-ml plastic syringe displayed the best result in providing steady food supply to bees. Finally, we also demonstrated that the addition of protein to the bees' diet could significantly increase the level ofvitellogenin gene expression and improve bees' survival. This international collaborative study represents a critical step toward improvement of cage designs and feeding regimes for honey bee laboratory experiments.

Resolving complex research data management issues in biomedical laboratories: Qualitative study of an industry-academia collaboration.

PubMed

Myneni, Sahiti; Patel, Vimla L; Bova, G Steven; Wang, Jian; Ackerman, Christopher F; Berlinicke, Cynthia A; Chen, Steve H; Lindvall, Mikael; Zack, Donald J

2016-04-01

This paper describes a distributed collaborative effort between industry and academia to systematize data management in an academic biomedical laboratory. Heterogeneous and voluminous nature of research data created in biomedical laboratories make information management difficult and research unproductive. One such collaborative effort was evaluated over a period of four years using data collection methods including ethnographic observations, semi-structured interviews, web-based surveys, progress reports, conference call summaries, and face-to-face group discussions. Data were analyzed using qualitative methods of data analysis to (1) characterize specific problems faced by biomedical researchers with traditional information management practices, (2) identify intervention areas to introduce a new research information management system called Labmatrix, and finally to (3) evaluate and delineate important general collaboration (intervention) characteristics that can optimize outcomes of an implementation process in biomedical laboratories. Results emphasize the importance of end user perseverance, human-centric interoperability evaluation, and demonstration of return on investment of effort and time of laboratory members and industry personnel for success of implementation process. In addition, there is an intrinsic learning component associated with the implementation process of an information management system. Technology transfer experience in a complex environment such as the biomedical laboratory can be eased with use of information systems that support human and cognitive interoperability. Such informatics features can also contribute to successful collaboration and hopefully to scientific productivity. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Influences of Learning Environment Characteristics on Student Learning During Authentic Science Inquiry in an Introductory Physical Geology Course

NASA Astrophysics Data System (ADS)

Miller, H. R.; Sell, K. S.; Herbert, B. E.

2004-12-01

Shifts in learning goals in introductory earth science courses to greater emphasis on critical thinking and the nature of science has led to the adoption of new pedagogical techniques, including inquiry-based learning (IBL). IBL is thought to support understanding of the nature of science and foster development of scientific reasoning and critical thinking skills by modeling authentic science inquiry. Implementation of new pedagogical techniques do not occur without influence, instruction and learning occurs in a complex learning environment, referring to the social, physical, mental, and pedagogical contexts. This study characterized the impact of an IBL module verses a traditionally structured laboratory exercise in an introductory physical geology class at Texas A&M University. Student activities in this study included manipulation of large-scale data sets, use of multiple representations, and exposure to ill-constrained problems common to the Texas Gulf Coast system. Formative assessment data collected included an initial survey of self efficacy, student demographics, content knowledge and a pre-mental model expression. Summative data collected included a post-test, post-mental model expression, final laboratory report, and a post-survey on student attitudes toward the module. Mental model expressions and final reports were scored according to a validated rubric instrument (Cronbrach alpha: 0.84-0.98). Nine lab sections were randomized into experimental and control groups. Experimental groups were taught using IBL pedagogical techniques, while the control groups were taught using traditional laboratory "workbook" techniques. Preliminary assessment based on rubric scores for pre-tests using Student's t-test (N ˜ 140) indicated that the experimental and control groups were not significantly different (ρ > 0.05), therefore, the learning environment likely impacted student's ability to succeed. A non-supportive learning environment, including student attitudes, teaching assistant attitudes, the lack of scaffolded learning, limited pedagogical content knowledge, and departmental oversight, which were all encountered during this study, can have an affect on the students' attitudes and achievements during the course. Data collected showed an overall improvement in content knowledge (38% increase); while performance effort clearly declined as seen through post-mental model expressions (a decline in performance by 24.8%) and percentage of assignments turned in (39% of all students turned in the required final report). A non-supportive learning environment was also seen through student comments on the final survey, "I think that all the TA's and the professor have forgotten that we are an intro class". A non-supportive environment clearly does not encourage critical thinking and completion of work. This pilot study showed that the complex learning environment can play a significant role in student learning. It also illustrates the need for future studies in IBL with supportive learning environments in order for students to achieve academic excellence and develop scientific reasoning and critical thinking skills.

Effects of surface chemistry on hot corrosion life

NASA Technical Reports Server (NTRS)

Fryxell, R. E.; Leese, G. E.

1985-01-01

This program has its primary objective: the development of hot corrosion life prediction methodology based on a combination of laboratory test data and evaluation of field service turbine components which show evidence of hot corrosion. The laboratory program comprises burner rig testing by TRW. A summary of results is given for two series of burner rig tests. The life prediction methodology parameters to be appraised in a final campaign of burner rig tests are outlined.

Tester Independent Support Software System (TISSS)

DTIC Science & Technology

1991-08-01

AD-A240 668 RL-TR-91-163 Final Technical Report August 1991 TESTER INDEPENDENT SUPPORT SOFTWARE SYSTEM (TISSS) Harris Corporation Dr. Robert Rolfe...Laboratory Air Force Systems Command Griffiss Air Force Base, NY 13441-5700 9_1 9 17 o15 This report has been reviewed by the Rome Laboratory Public...will assist us in maintaining a current mailing list. Do not return copies of this report unless contractual obligations or notices on a specific

Quantification of Noise Sources in EMI Surveys

DTIC Science & Technology

2012-04-09

Naval Research Laboratory Washington, DC 20375-5320 NRL/MR/ 6110 --12-9400 Quantification of Noise Sources in EMI Surveys ESTCP MR-0508 Final Guidance...NUMBER 2 . REPORT TYPE1. REPORT DATE (DD-MM-YYYY) 4. TITLE AND SUBTITLE 6. AUTHOR(S) 8. PERFORMING ORGANIZATION REPORT NUMBER 7. PERFORMING...Barrow,‡ Jonathan T. Miller,‡ and Thomas H. Bell,‡ Naval Research Laboratory, Code 6110 4555 Overlook Avenue, SW Washington, DC 20375-5320 NRL/MR

78 FR 66936 - Issuance of Final Guidance Publication

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-07

... Immediately Dangerous to Life or Health (IDLH) Values'' [NIOSH 2014-100]. ADDRESSES: This document may be.... Scott Dotson, Ph.D. CIH, NIOSH Education and Information Division, Taft Laboratories Building, 4676...

A refuge for inorganic chemistry: Bunsen's Heidelberg laboratory.

PubMed

Nawa, Christine

2014-05-01

Immediately after its opening in 1855, Bunsen's Heidelberg laboratory became iconic as the most modern and best equipped laboratory in Europe. Although comparatively modest in size, the laboratory's progressive equipment made it a role model for new construction projects in Germany and beyond. In retrospect, it represents an intermediate stage of development between early teaching facilities, such as Liebig's laboratory in Giessen, and the new 'chemistry palaces' that came into existence with Wöhler's Göttingen laboratory of 1860. As a 'transition laboratory,' Bunsen's Heidelberg edifice is of particular historical interest. This paper explores the allocation of spaces to specific procedures and audiences within the laboratory, and the hierarchies and professional rites of passage embedded within it. On this basis, it argues that the laboratory in Heidelberg was tailored to Bunsen's needs in inorganic and physical chemistry and never aimed at a broad-scale representation of chemistry as a whole. On the contrary, it is an example of early specialisation within a chemical laboratory preceding the process of differentiation into chemical sub-disciplines. Finally, it is shown that the relatively small size of this laboratory, and the fact that after ca. 1860 no significant changes were made within the building, are inseparably connected to Bunsen's views on chemistry teaching.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kavet, R.; Tell, R.A.

As the use of video display terminals (VDTs) has expanded, questions have been raised as to whether working at a VDT affects the risk of adverse pregnancy outcome. A particular focus for these questions has been the very low frequency (VLF) magnetic field produced by a VDT's horizontal deflection coil. VDTs also produce VLF electric fields, extremely low frequency (ELF) electric and magnetic fields, and static electric fields, Ten studies of pregnancy outcome in VDT operators have been conducted in six countries, and with one exception, none has concluded that magnetic fields from VDTs may predispose pregnant operators to spontaneousmore » abortion or congenital malformation. The epidemiologic studies conducted thus far do not provide a basis for concluding that VDT work and adverse pregnancy outcome are associated. Studies of fetal resorptions and malformations in rodents exposed to VLF magnetic fields have produced inconsistent findings. Two laboratories in Sweden that studied mice have reported positive results, one laboratory showing field-related malformations (but not resorptions) and the other showing field-related resorptions (but not malformations). Two Canadian laboratories have reported negative results in rats and mice. Studies of avian embryos have also yielded inconsistent results, but lacking a maternal-fetal placental interface, avian embryos are a questionable model for evaluating human reproductive risks. Finally, VLF electric and magnetic fields measured at the operator position are in compliance with field strength standards and guidelines that have been established around the world. 55 refs.« less

Comparative analytical evaluation of the respiratory TaqMan Array Card with real-time PCR and commercial multi-pathogen assays.

PubMed

Harvey, John J; Chester, Stephanie; Burke, Stephen A; Ansbro, Marisela; Aden, Tricia; Gose, Remedios; Sciulli, Rebecca; Bai, Jing; DesJardin, Lucy; Benfer, Jeffrey L; Hall, Joshua; Smole, Sandra; Doan, Kimberly; Popowich, Michael D; St George, Kirsten; Quinlan, Tammy; Halse, Tanya A; Li, Zhen; Pérez-Osorio, Ailyn C; Glover, William A; Russell, Denny; Reisdorf, Erik; Whyte, Thomas; Whitaker, Brett; Hatcher, Cynthia; Srinivasan, Velusamy; Tatti, Kathleen; Tondella, Maria Lucia; Wang, Xin; Winchell, Jonas M; Mayer, Leonard W; Jernigan, Daniel; Mawle, Alison C

2016-02-01

In this study, a multicenter evaluation of the Life Technologies TaqMan(®) Array Card (TAC) with 21 custom viral and bacterial respiratory assays was performed on the Applied Biosystems ViiA™ 7 Real-Time PCR System. The goal of the study was to demonstrate the analytical performance of this platform when compared to identical individual pathogen specific laboratory developed tests (LDTs) designed at the Centers for Disease Control and Prevention (CDC), equivalent LDTs provided by state public health laboratories, or to three different commercial multi-respiratory panels. CDC and Association of Public Health Laboratories (APHL) LDTs had similar analytical sensitivities for viral pathogens, while several of the bacterial pathogen APHL LDTs demonstrated sensitivities one log higher than the corresponding CDC LDT. When compared to CDC LDTs, TAC assays were generally one to two logs less sensitive depending on the site performing the analysis. Finally, TAC assays were generally more sensitive than their counterparts in three different commercial multi-respiratory panels. TAC technology allows users to spot customized assays and design TAC layout, simplify assay setup, conserve specimen, dramatically reduce contamination potential, and as demonstrated in this study, analyze multiple samples in parallel with good reproducibility between instruments and operators. Copyright © 2015 Elsevier B.V. All rights reserved.

Mixed waste landfill corrective measures study final report Sandia National Laboratories, Albuquerque, New Mexico.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peace, Gerald; Goering, Timothy James

2004-03-01

The Mixed Waste Landfill occupies 2.6 acres in the north-central portion of Technical Area 3 at Sandia National Laboratories, Albuquerque, New Mexico. The landfill accepted low-level radioactive and mixed waste from March 1959 to December 1988. This report represents the Corrective Measures Study that has been conducted for the Mixed Waste Landfill. The purpose of the study was to identify, develop, and evaluate corrective measures alternatives and recommend the corrective measure(s) to be taken at the site. Based upon detailed evaluation and risk assessment using guidance provided by the U.S. Environmental Protection Agency and the New Mexico Environment Department, themore » U.S. Department of Energy and Sandia National Laboratories recommend that a vegetative soil cover be deployed as the preferred corrective measure for the Mixed Waste Landfill. The cover would be of sufficient thickness to store precipitation, minimize infiltration and deep percolation, support a healthy vegetative community, and perform with minimal maintenance by emulating the natural analogue ecosystem. There would be no intrusive remedial activities at the site and therefore no potential for exposure to the waste. This alternative poses minimal risk to site workers implementing institutional controls associated with long-term environmental monitoring as well as routine maintenance and surveillance of the site.« less

Quality in laboratory medicine: 50years on.

PubMed

Plebani, Mario

2017-02-01

The last 50years have seen substantial changes in the landscape of laboratory medicine: its role in modern medicine is in evolution and the quality of laboratory services is changing. The need to control and improve quality in clinical laboratories has grown hand in hand with the growth in technological developments leading to an impressive reduction of analytical errors over time. An essential cause of this impressive improvement has been the introduction and monitoring of quality indicators (QIs) such as the analytical performance specifications (in particular bias and imprecision) based on well-established goals. The evolving landscape of quality and errors in clinical laboratories moved first from analytical errors to all errors performed within the laboratory walls, subsequently to errors in laboratory medicine (including errors in test requesting and result interpretation), and finally, to a focus on errors more frequently associated with adverse events (laboratory-associated errors). After decades in which clinical laboratories have focused on monitoring and improving internal indicators of analytical quality, efficiency and productivity, it is time to shift toward indicators of total quality, clinical effectiveness and patient outcomes. Copyright © 2016 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

Pre-clinical toxicology considerations for vaccine development.

PubMed

Al-Humadi, Nabil

2017-10-13

Vaccine development requires pre-clinical toxicology studies, following good laboratory practice (GLP), before first in human (phase I) use. Many factors are critical in the final outcome of any pre-clinical toxicology study. The study design is one of these critical factors and should be carefully planned to avoid any false negative and/or false positive results. Preparation is another most critical factor in a successful study. Major changes in any procedure during the course of study should be avoided by all means. For example, if the protocol specified the tail as the site of blood collection and this procedure was used for the control group at the day of necropsy, this collection site should never be replaced by another site (e.g. foot, eye, or heart) in all other treatment groups. Food restrictions and acute restraint stress affect clinical pathology data and should be avoided in rodents. Institutional Animal Care and Use Committee (IACUC) guidelines for frequent blood collections (weekly, monthly, or at necropsy) in any animal species should be strictly followed. Clinical pathology data will be profoundly affected by any diversion from the recommended volumes. If CO 2 is specified in the protocol for anesthesia and/or euthanasia, ensuring enough quantity to use for all groups at necropsy is a very important factor. Using two different anesthetics in any study (e.g. CO 2 vs. pentobarbital) may result in false positive or false negative results in clinical chemistry parameters. Quality assurance elements (SOPs, instrument validation, lab certification etc.) affect the data interpretation and the final outcome of any toxicology study. SOPs should be up to date and written clearly. All lab instruments should be validated and all laboratories should be certified. Published by Elsevier Ltd.

Choice of experimental venue matters in ecotoxicology studies: Comparison of a laboratory-based and an outdoor mesocosm experiment.

PubMed

Mikó, Zsanett; Ujszegi, János; Gál, Zoltán; Imrei, Zoltán; Hettyey, Attila

2015-10-01

The heavy application of pesticides and its potential effects on natural communities has attracted increasing attention to inadvertent impacts of these chemicals. Toxicologists conventionally use laboratory-based tests to assess lethal concentrations of pesticides. However, these tests often do not take into account indirect, interactive and long-term effects, and tend to ignore different rates of disintegration in the laboratory and under natural conditions. Our aim was to investigate the importance of the experimental venue for ecotoxicology tests. We reared tadpoles of the agile frog (Rana dalmatina) in the laboratory and in outdoor mesocosms and exposed them to three initial concentrations of a glyphosate-based herbicide (0, 2 and 6.5 mg a.e./L glyphosate), and to the presence or absence of caged predators (dragonfly larvae). The type of experimental venue had a large effect on the outcome: The herbicide was less lethal to tadpoles reared in outdoor mesocosms than in the laboratory. Further, while the herbicide had a negative effect on development time and on body mass in the laboratory, tadpoles exposed to the herbicide in mesocosms were larger at metamorphosis and developed faster in comparison to those reared in the absence of the herbicide. The effect of the herbicide on morphological traits of tadpoles also differed between the two venues. Finally, in the presence of the herbicide, tadpoles tended to be more active and to stay closer to the bottom of laboratory containers, while tadpole behaviour shifted in the opposite direction in outdoor mesocosms. Our results demonstrate major discrepancies between results of a classic laboratory-based ecotoxicity test and outcomes of an experiment performed in outdoor mesocosms. Consequently, the use of standard laboratory tests may have to be reconsidered and their benefits carefully weighed against the difficulties of performing experiments under more natural conditions. Tests validating experimentally estimated impacts of herbicides under natural conditions and studies identifying key factors determining the applicability of experimental results are urgently needed. Copyright © 2015 Elsevier B.V. All rights reserved.

PILOT STUDY: Report on the CCPR Pilot Comparison: Spectral Responsivity 10 nm to 20 nm

NASA Astrophysics Data System (ADS)

Scholze, Frank; Vest, Robert; Saito, Terubumi

2010-01-01

The CCPR Pilot Comparison on spectral responsivity in the 10 nm to 20 nm spectral range was carried out within the framework of the CIPM Mutual Recognition Arrangement by three laboratories: PTB (Germany), NIST (USA), and NMIJ/AIST (Japan) with PTB acting as the central and reporting laboratory. All participating laboratories used monochromatized synchrotron radiation. PTB and NIST used a cryogenic radiometer as the primary standard detector and NMIJ, an ionization chamber with extrapolation by a wavelength-independent detector. The aim of the pilot comparison was to check the accuracy of the radiometric scale of spectral responsivity in the short wavelength EUV spectral range which has recently gained in technological importance. The wavelengths of measurement were from 11.5 nm to 20 nm in 0.5 nm steps and additionally 12.2 nm. The comparison was carried out through the calibration of a group of transfer standard detectors. Two sets of three diodes of types AXUV and SXUV from International Radiation Detectors, Inc. were used for the comparison. The comparison had the form of a star comparison: Pilot-lab A-pilot-lab B-pilot, PTB acting as the pilot laboratory. All results were communicated directly to the pilot laboratory. The report describes in detail the measurements made at PTB and summarizes the reports submitted by the participants. Measurements carried out by the pilot laboratory before and after the circulation of the detectors proved that the stability of the detectors was sufficient for the comparison. For the type AXUV detectors, however, changes in their responsivity contributed to the uncertainty of the comparison. Measurement results from participants and their associated uncertainties were analyzed in this report according to the Guidelines for CCPR Comparison Report Preparation. The uncertainty contributions were separated, as to whether they are wavelength dependent or not. All bilateral DoE are well within the respective k = 2 expanded uncertainty ranges for all wavelengths. The separated non-wavelength-dependent and wavelength-dependent uncertainty contributions are consistent with the respective wavelength-averaged DoE and wavelength-dependent variations of all bilateral DoE. Main text. To reach the main text of this paper, click on Final Report. The final report has been peer-reviewed and approved for publication by the CCPR WG-KC

Thai clinical laboratory responsible to economic crisis.

PubMed

Sirisali, K; Vattanaviboon, P; Manochiopinij, S; Ananskulwat, W

1999-01-01

Nowadays, Thailand encounters a serious economic crisis. A clear consensus has been made that a cost-saving system must be the important tool. Both private and government organizations are engaged in this situation. We studied the cost-saving in the clinical laboratory. A questionnaire was distributed to 45 hospital laboratories located in Bangkok. Results showed that efforts to control the cost are the essential policy. There was a variety of factors contributing to the cost-saving process. The usage of public utility, non-recycle material and unnecessary utility were reconsidered. Besides, capital cost (wages and salary) personnel incentive are assessed. Forty three of the 45 respondents had attempted to reduce the cost via curtailing the unnecessary electricity. Eliminating the needless usage of telephone-call. water and unnecessary material was also an effective strategy. A reduction of 86.9%, 80 % and 80.0% of the mentioned factors respectively, was reported. An inventory system of the reagent, chemical and supplies was focused. Most of the laboratories have a policy on cost-saving by decreased the storage. Twenty eight of the 45 laboratories considered to purchase the cheaper with similar quality reagents instead. And some one would purchase a bulky pack when it is the best bargain. A specific system "contact reagent with a free rent instrument" has been used widely (33.3%). Finally, a new personnel management system has been chosen. Workload has rearranged and unnecessary extra-hour work was abandoned.

USAF Summer Research Program - 1993 Summer Research Extension Program Final Reports, Volume 1B, Armstrong Laboratory

DTIC Science & Technology

1994-11-01

For example, the Collimating scotopic components of the ERG flash response are significantly attenuated by retinitis pigmentosa [7]. It is possible... RETINAL DAMAGE Bernard S. Gerstman Associate Professor Department of Physics Florida International University University Park Miami, FL 33199 Final...and Florida International University April 1994 6-1 A COMPUTATIONAL THERMAL MODEL AND THEORETICAL THERMODYNAMIC MODEL OF LASER INDUCED RETINAL DAMAGE

RealTime Physics: Active learning laboratory

NASA Astrophysics Data System (ADS)

Thornton, Ronald K.; Sokoloff, David R.

1997-03-01

Our research shows that student learning of physics concepts in introductory physics courses is enhanced by the use of special guided discovery laboratory curricula which embody the results of educational research and which are supported by the use of the Tools for Scientific Thinking microcomputer-based laboratory (MBL) tools. In this paper we first describe the general characteristics of the research-based RealTime Physics laboratory curricula developed for use in introductory physics classes in colleges, universities and high schools. We then describe RealTime Physics Mechanics in detail. Finally we examine student learning of dynamics in traditional physics courses and in courses using RealTime Physics Mechanics, primarily by the use of correlated questions on the Force and Motion Conceptual Evaluation. We present considerable evidence that students who use the new laboratory curricula demonstrate significantly improved learning and retention of dynamics concepts compared to students taught by traditional methods.

Achieving external validity in home advantage research: generalizing crowd noise effects

PubMed Central

Myers, Tony D.

2014-01-01

Different factors have been postulated to explain the home advantage phenomenon in sport. One plausible explanation investigated has been the influence of a partisan home crowd on sports officials' decisions. Different types of studies have tested the crowd influence hypothesis including purposefully designed experiments. However, while experimental studies investigating crowd influences have high levels of internal validity, they suffer from a lack of external validity; decision-making in a laboratory setting bearing little resemblance to decision-making in live sports settings. This focused review initially considers threats to external validity in applied and theoretical experimental research. Discussing how such threats can be addressed using representative design by focusing on a recently published study that arguably provides the first experimental evidence of the impact of live crowd noise on officials in sport. The findings of this controlled experiment conducted in a real tournament setting offer a level of confirmation of the findings of laboratory studies in the area. Finally directions for future research and the future conduct of crowd noise studies are discussed. PMID:24917839

Phenomenological Modeling and Laboratory Simulation of Long-Term Aging of Asphalt Mixtures

NASA Astrophysics Data System (ADS)

Elwardany, Michael Dawoud

The accurate characterization of asphalt mixture properties as a function of pavement service life is becoming more important as more powerful pavement design and performance prediction methods are implemented. Oxidative aging is a major distress mechanism of asphalt pavements. Aging increases the stiffness and brittleness of the material, which leads to a high cracking potential. Thus, an improved understanding of the aging phenomenon and its effect on asphalt binder chemical and rheological properties will allow for the prediction of mixture properties as a function of pavement service life. Many researchers have conducted laboratory binder thin-film aging studies; however, this approach does not allow for studying the physicochemical effects of mineral fillers on age hardening rates in asphalt mixtures. Moreover, aging phenomenon in the field is governed by kinetics of binder oxidation, oxygen diffusion through mastic phase, and oxygen percolation throughout the air voids structure. In this study, laboratory aging trials were conducted on mixtures prepared using component materials of several field projects throughout the USA and Canada. Laboratory aged materials were compared against field cores sampled at different ages. Results suggested that oven aging of loose mixture at 95°C is the most promising laboratory long-term aging method. Additionally, an empirical model was developed in order to account for the effect of mineral fillers on age hardening rates in asphalt mixtures. Kinetics modeling was used to predict field aging levels throughout pavement thickness and to determine the required laboratory aging duration to match field aging. Kinetics model outputs are calibrated using measured data from the field to account for the effects of oxygen diffusion and percolation. Finally, the calibrated model was validated using independent set of field sections. This work is expected to provide basis for improved asphalt mixture and pavement design procedures in order to save taxpayers' money.

The Los Alamos universe: Using multimedia to promote laboratory capabilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kindel, J.

2000-03-01

This project consists of a multimedia presentation that explains the technological capabilities of Los Alamos National Laboratory. It takes the form of a human-computer interface built around the metaphor of the universe. The project is intended promote Laboratory capabilities to a wide audience. Multimedia is simply a means of communicating information through a diverse set of tools--be they text, sound, animation, video, etc. Likewise, Los Alamos National Laboratory is a collection of diverse technologies, projects, and people. Given the ample material available at the Laboratory, there are tangible benefits to be gained by communicating across media. This paper consists ofmore » three parts. The first section provides some basic information about the Laboratory, its mission, and its needs. The second section introduces this multimedia presentation and the metaphor it is based on along with some basic concepts of color and user interaction used in the building of this project. The final section covers construction of the project, pitfalls, and future improvements.« less

The development and assessment of constructivist-based curriculum changes in a university general biology laboratory course

NASA Astrophysics Data System (ADS)

Herron, Sherry Shelton

1999-11-01

This study describes the processes involved in transforming the curriculum of the second semester general biology laboratory course for science majors, BSC 111L, at the University of Southern Mississippi from one based on the behaviorist model of teaching and learning to one based on the constructivist model. The study encompasses pilot and research phases. During the pilot phase conducted fall semester of 1997, the researcher presented to graduate teaching assistants an overview of the need for curriculum reform and some of the theoretical underpinnings for the movement. The researcher worked with all of the general biology teaching assistants to determine factors they considered supportive of the effort, identified specific goals and exercises, and developed a mission statement. The researcher then worked with two of the teaching assistants to write the new curriculum materials and pilot them in a designated laboratory section each week. During the research phase, the researcher facilitated the use of constructivist teaching methods and interviewed the teaching assistants during weekly group meetings. The researcher videotaped and observed the laboratories at various times throughout spring semester of 1998. Student responses to survey questions about the laboratories were collected during the observation sessions. Data derived from self-assessments on teaching beliefs completed by the teaching assistants, interview transcripts, videotaped laboratory sessions, and student surveys were used to assess the effectiveness of the new curriculum and the intervention program. It was observed that despite being given the same instructions, curriculum, and materials, each teaching assistant conducted his laboratory section in a unique way and rarely conducted the complete laboratory in the intended manner. It was also observed that one TA in particular needed more training in interpersonal skill development and content than was provided during the weekly intervention sessions. However, it was evident that constructivist teaching methods were being learned and that constructivist goals were being realized. Strengths and weaknesses of the curriculum materials were identified and extensive revisions were made by the researcher prior to the next semester. Finally, recommendations pertinent to the student survey used in this study (the Student Outcome Assessment Rubric) were made, and the need for more pedagogical instruction for teaching assistants and a mechanism to integrate lecture materials to the laboratory experience was described.

Final report of the APMP water flow key comparison: APMP.M.FF-K1

NASA Astrophysics Data System (ADS)

Lee, Kwang-Bock; Chun, Sejong; Terao, Yoshiya; Thai, Nguyen Hong; Tsair Yang, Cheng; Tao, Meng; Gutkin, Mikhail B.

2011-01-01

The key comparison, APMP.M.FF-K1, was undertaken by APMP/TCFF, the Technical Committee for Fluid Flow (TCFF) under the Asia Pacific Metrology Program (APMP). One objective of the key comparison was to demonstrate the degree of equivalence among six participating laboratories (KRISS, NMIJ, VMI, CMS, NIM and VNIIM) in water flow rate metrology by comparing the results with the key comparison reference value (KCRV) determined from the CCM.FF-K1 key comparison. The other objective of this key comparison was to provide supporting evidence for the calibration and measurement capabilities (CMCs), which had been declared by the participating laboratories during this key comparison. The Transfer Standard Package (TSP) was a Coriolis mass flowmeter, which had been used in the CCM.FF-K1 key comparison. Because the K-factors in the APMP.M.FF-K1 key comparison were slightly lower than the K-factors of the CCM.FF-K1 key comparison due to long-term drifts of the TSP, a correction value D was introduced. The value of D was given by a weighted sum between two link laboratories (NMIJ and KRISS), which participated in both the CCM.FF-K1 and the APMP.M.FF-K1 key comparisons. By this correction, the K-factors were laid between 12.004 and 12.017 at either low (Re = 254 000) or high (Re = 561 000) flow rates. Most of the calibration data were within expected uncertainty bounds. However, some data showed undulations, which gave large fluctuations of the metering factor at Re = 561 000. Calculation of degrees of equivalence showed that all the participating laboratories had deviations between -0.009 and 0.007 pulses/kg from the CCM.FF-K1 KCRV at either the low or the high flow rates. In case of En calculation, all the participating laboratories showed values less than 1, indicating that the corrected K-factors of all the laboratories were equivalent with the KCRV at both Re = 254 000 and 561 000. When the corrected K-factors from two participating laboratories were compared, all the numbers of equivalence showed values less than 1, indicating equivalence. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).

Gasoline and Diesel Fuel Test Methods Additional Resources

EPA Pesticide Factsheets

Supporting documents on the Direct Final Rule that allows refiners and laboratories to use more current and improved fuel testing procedures for twelve American Society for Testing and Materials analytical test methods.

International Space Station (ISS)

NASA Image and Video Library

1994-09-21

Artist's concept of the final configuration of the International Space Station (ISS) Alpha. The ISS is a multidisciplinary laboratory, technology test bed, and observatory that will provide an unprecedented undertaking in scientific, technological, and international experimentation.

Early Experience after Developing a Pathology Laboratory in Malawi, with Emphasis on Cancer Diagnoses

PubMed Central

Horner, Marie-Josephe; Shores, Carol G.; Alide, Noor; Kamiza, Steve; Kampani, Coxcilly; Chimzimu, Fred; Fedoriw, Yuri; Dittmer, Dirk P.; Hosseinipour, Mina C.; Hoffman, Irving F.

2013-01-01

Background Despite increasing cancer burden in Malawi, pathology services are limited. We describe operations during the first 20 months of a new pathology laboratory in Lilongwe, with emphasis on cancer diagnoses. Methods and Findings We performed a cross-sectional study of specimens from the Kamuzu Central Hospital pathology laboratory between July 1, 2011 and February 28, 2013. Patient and specimen characteristics, and final diagnoses are summarized. Diagnoses were categorized as malignant, premalignant, infectious, other pathology, normal or benign, or nondiagnostic. Patient characteristics associated with premalignancy and malignancy were assessed using logistic regression. Of 2772 specimens, 2758 (99%) with a recorded final diagnosis were included, drawn from 2639 unique patients. Mean age was 38 years and 63% were female. Of those with documented HIV status, 51% had unknown status, and 36% with known status were infected. Histologic specimens comprised 91% of cases, and cytologic specimens 9%. Malignant diagnoses were most common overall (n = 861, 31%). Among cancers, cervical cancer was most common (n = 117, 14%), followed by lymphoma (n = 91, 11%), esophageal cancer (n = 86, 10%), sarcoma excluding Kaposi sarcoma (n = 75, 9%), and breast cancer (n = 61, 7%). HIV status was known for 95 (11%) of malignancies, with HIV prevalence ranging from 9% for breast cancer to 81% for cervical cancer. Increasing age was consistently associated with malignancy [bivariable odds ratio 1.24 per decade increase (95% CI 1.19–1.29) among 2685 patients with known age; multivariable odds ratio 1.33 per decade increase (95% CI 1.14–1.56) among 317 patients with known age, gender, and HIV status], while HIV infection and gender were not. Conclusions Despite selection and referral bias inherent in these data, a new pathology laboratory in Lilongwe has created a robust platform for cancer care and research. Strategies to effectively capture clinical information for pathologically confirmed cancers can allow these data to complement population-based registration. PMID:23950924

[ISO 15189, Up-To-Date Information and Prospective View].

PubMed

Shimoda, Katsuji

2016-02-01

"Accreditation Activities for Medical Laboratories in Japan" Audits for transition to ISO 15189:2012 continue to progress. Besides the continual increase of accreditations for medical laboratory testing and pathological examinations, preparations for the addition of physiological testing to the scope of accreditation have finally been completed. As a part of the revision to Japan's Medical Service Act, the external evaluation of medical laboratories is now a requirement to approve clinical trial core hospitals. Accordingly, the importance of third-party accreditation in medical laboratory testing is attracting a growing level of attention. World Accreditation Day 2015 "Accreditation: Supporting the Delivery of Health and Social Care" JAB is being used to make every effort to contribute to this system in order to improve the quality of healthcare in Japan and the health of its citizens.

Final report: Prototyping a combustion corridor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rutland, Christopher J.; Leach, Joshua

2001-12-15

The Combustion Corridor is a concept in which researchers in combustion and thermal sciences have unimpeded access to large volumes of remote computational results. This will enable remote, collaborative analysis and visualization of state-of-the-art combustion science results. The Engine Research Center (ERC) at the University of Wisconsin - Madison partnered with Lawrence Berkeley National Laboratory, Argonne National Laboratory, Sandia National Laboratory, and several other universities to build and test the first stages of a combustion corridor. The ERC served two important functions in this partnership. First, we work extensively with combustion simulations so we were able to provide real worldmore » research data sets for testing the Corridor concepts. Second, the ERC was part of an extension of the high bandwidth based DOE National Laboratory connections to universities.« less

Laboratory medicine and sports: between Scylla and Charybdis.

PubMed

Lippi, Giuseppe; Banfi, Giuseppe; Botrè, Francesco; de la Torre, Xavier; De Vita, Francesco; Gomez-Cabrera, Mari Carmen; Maffulli, Nicola; Marchioro, Lucio; Pacifici, Roberta; Sanchis-Gomar, Fabian; Schena, Federico; Plebani, Mario

2012-02-28

Laboratory medicine is complex and contributes to the diagnosis, therapeutic monitoring and follow-up of acquired and inherited human disorders. The regular practice of physical exercise provides important benefits in heath and disease and sports medicine is thereby receiving growing focus from almost each and every clinical discipline, including laboratory medicine. Sport-laboratory medicine is a relatively innovative branch of laboratory science, which can provide valuable contributions to the diagnosis and follow-up of athletic injuries, and which is acquiring a growing clinical significance to support biomechanics and identify novel genomics and "exercisenomics" patterns that can help identify specific athlete's tendency towards certain types of sport traumas and injuries. Laboratory medicine can also provide sport physicians and coaches with valuable clues about personal inclination towards a certain sport, health status, fitness and nutritional deficiencies of professional, elite and recreational athletes in order to enable a better and earlier prediction of sport injuries, overreaching and overtraining. Finally, the wide armamentarium of laboratory tests represents the milestone for identifying cheating athletes in the strenuous fight against doping in sports.

Radiation effects in astrophysical ices

NASA Astrophysics Data System (ADS)

Boduch, Philippe; Dartois, Emmanuel; de Barros, Ana L. F.; da Silveira, Enio F.; Domaracka, Alicja; Lv, Xue-Yang; Palumbo, Maria Elisabetta; Pilling, Sergio; Rothard, Hermann; Seperuelo Duarte, Eduardo; Strazzulla, Giovanni

2015-07-01

The interaction of heavy ions with astrophysical ices was studied at different beamlines of GANIL by infrared absorption spectroscopy. This allowed simulating in the laboratory the physico-chemical modifications induced in icy objects in space, exposed to radiation fields such as the solar wind, magnetospheric particles and interstellar cosmic rays. We briefly discuss sputtering, destruction and formation of molecules, amorphization and compaction, implantation, and finally the formation of organic molecules. This latter topic is related to the question of the initial conditions for the emergence of life.

Computer Code Gives Astrophysicists First Full Simulation of Star's Final Hours

ScienceCinema

Andy Nonaka

2017-12-09

The precise conditions inside a white dwarf star in the hours leading up to its explosive end as a Type Ia supernova are one of the mysteries confronting astrophysicists studying these massive stellar explosions. But now, a team of researchers, composed of three applied mathematicians at the U.S. Department of Energy's (DOE) Lawrence Berkeley National Laboratory and two astrophysicists, has created the first full-star simulation of the hours preceding the largest thermonuclear explosions in the universe.

Human embryo culture media comparisons.

PubMed

Pool, Thomas B; Schoolfield, John; Han, David

2012-01-01

Every program of assisted reproduction strives to maximize pregnancy outcomes from in vitro fertilization and selecting an embryo culture medium, or medium pair, consistent with high success rates is key to this process. The common approach is to replace an existing medium with a new one of interest in the overall culture system and then perform enough cycles of IVF to see if a difference is noted both in laboratory measures of embryo quality and in pregnancy. This approach may allow a laboratory to select one medium over another but the outcomes are only relevant to that program, given that there are well over 200 other variables that may influence the results in an IVF cycle. A study design that will allow for a more global application of IVF results, ones due to culture medium composition as the single variable, is suggested. To perform a study of this design, the center must have a patient caseload appropriate to meet study entrance criteria, success rates high enough to reveal a difference if one exists and a strong program of quality assurance and control in both the laboratory and clinic. Sibling oocytes are randomized to two study arms and embryos are evaluated on day 3 for quality grades. Inter and intra-observer variability are evaluated by kappa statistics and statistical power and study size estimates are performed to bring discriminatory capability to the study. Finally, the complications associated with extending such a study to include blastocyst production on day 5 or 6 are enumerated.

Prediction of Wind Energy Resources (PoWER) Users Guide

DTIC Science & Technology

2016-01-01

ARL-TR-7573● JAN 2016 US Army Research Laboratory Prediction of Wind Energy Resources (PoWER) User’s Guide by David P Sauter...not return it to the originator. ARL-TR-7573 ● JAN 2016 US Army Research Laboratory Prediction of Wind Energy Resources (PoWER...2016 2. REPORT TYPE Final 3. DATES COVERED (From - To) 09/2015–11/2015 4. TITLE AND SUBTITLE Prediction of Wind Energy Resources (PoWER) User’s

Reducing environmental risk associated with laboratory decommissioning and property transfer.

PubMed

Dufault, R; Abelquist, E; Crooks, S; Demers, D; DiBerardinis, L; Franklin, T; Horowitz, M; Petullo, C; Sturchio, G

2000-12-01

The need for more or less space is a common laboratory problem. Solutions may include renovating existing space, leaving or demolishing old space, or acquiring new space or property for building. All of these options carry potential environmental risk. Such risk can be the result of activities related to the laboratory facility or property (e.g., asbestos, underground storage tanks, lead paint), or the research associated with it (e.g., radioactive, microbiological, and chemical contamination). Regardless of the option chosen to solve the space problem, the potential environmental risk must be mitigated and the laboratory space and/or property must be decommissioned or rendered safe prior to any renovation, demolition, or property transfer activities. Not mitigating the environmental risk through a decommissioning process can incur significant financial liability for any costs associated with future decommissioning cleanup activities. Out of necessity, a functioning system, environmental due diligence auditing, has evolved over time to assess environmental risk and reduce associated financial liability. This system involves a 4-phase approach to identify, document, manage, and clean up areas of environmental concern or liability, including contamination. Environmental due diligence auditing includes a) historical site assessment, b) characterization assessment, c) remedial effort and d) final status survey. General practice standards from the American Society for Testing and Materials are available for conducting the first two phases. However, standards have not yet been developed for conducting the third and final phases of the environmental due diligence auditing process. Individuals involved in laboratory decommissioning work in the biomedical research industry consider this a key weakness.

From Laboratory Research to a Clinical Trial

PubMed Central

Michels, Harold T.; Keevil, C. William; Salgado, Cassandra D.; Schmidt, Michael G.

2015-01-01

Objective: This is a translational science article that discusses copper alloys as antimicrobial environmental surfaces. Bacteria die when they come in contact with copper alloys in laboratory tests. Components made of copper alloys were also found to be efficacious in a clinical trial. Background: There are indications that bacteria found on frequently touched environmental surfaces play a role in infection transmission. Methods: In laboratory testing, copper alloy samples were inoculated with bacteria. In clinical trials, the amount of live bacteria on the surfaces of hospital components made of copper alloys, as well as those made from standard materials, was measured. Finally, infection rates were tracked in the hospital rooms with the copper components and compared to those found in the rooms containing the standard components. Results: Greater than a 99.9% reduction in live bacteria was realized in laboratory tests. In the clinical trials, an 83% reduction in bacteria was seen on the copper alloy components, when compared to the surfaces made from standard materials in the control rooms. Finally, the infection rates were found to be reduced by 58% in patient rooms with components made of copper, when compared to patients' rooms with components made of standard materials. Conclusions: Bacteria die on copper alloy surfaces in both the laboratory and the hospital rooms. Infection rates were lowered in those hospital rooms containing copper components. Thus, based on the presented information, the placement of copper alloy components, in the built environment, may have the potential to reduce not only hospital-acquired infections but also patient treatment costs. PMID:26163568

Reducing environmental risk associated with laboratory decommissioning and property transfer.

PubMed Central

Dufault, R; Abelquist, E; Crooks, S; Demers, D; DiBerardinis, L; Franklin, T; Horowitz, M; Petullo, C; Sturchio, G

2000-01-01

The need for more or less space is a common laboratory problem. Solutions may include renovating existing space, leaving or demolishing old space, or acquiring new space or property for building. All of these options carry potential environmental risk. Such risk can be the result of activities related to the laboratory facility or property (e.g., asbestos, underground storage tanks, lead paint), or the research associated with it (e.g., radioactive, microbiological, and chemical contamination). Regardless of the option chosen to solve the space problem, the potential environmental risk must be mitigated and the laboratory space and/or property must be decommissioned or rendered safe prior to any renovation, demolition, or property transfer activities. Not mitigating the environmental risk through a decommissioning process can incur significant financial liability for any costs associated with future decommissioning cleanup activities. Out of necessity, a functioning system, environmental due diligence auditing, has evolved over time to assess environmental risk and reduce associated financial liability. This system involves a 4-phase approach to identify, document, manage, and clean up areas of environmental concern or liability, including contamination. Environmental due diligence auditing includes a) historical site assessment, b) characterization assessment, c) remedial effort and d) final status survey. General practice standards from the American Society for Testing and Materials are available for conducting the first two phases. However, standards have not yet been developed for conducting the third and final phases of the environmental due diligence auditing process. Individuals involved in laboratory decommissioning work in the biomedical research industry consider this a key weakness. PMID:11121365

The Influence of Alumina Properties on its Dissolution in Smelting Electrolyte

NASA Astrophysics Data System (ADS)

Bagshaw, A. N.; Welch, B. J.

The dissolution of a wide range of commercially produced aluminas in modified cryolite bath was studied on a laboratory scale. Most of the aluminas were products of conventional refineries and smelter dry scrubbing systems; a few were produced in laboratory and pilot calciners, enabling greater flexibility in the calcination process and the final properties. The mode of alumina feeding and the size of addition approximated to the point feeder situation. Alpha-alumina content, B.E.T. surface area and median particle size had little impact on dissolution behaviour. The volatiles content, expressed as L.O.I., the morphology of the original hydrate and the mode of calcination had the most influence. Discrete intermediate oxide phases were identified in all samples; delta-alumina content impacted most on dissolution. The flow properties of an alumina affected its overall dissolution.

KEY COMPARISON: Final report on CCQM-K69 key comparison: Testosterone glucuronide in human urine

NASA Astrophysics Data System (ADS)

Liu, Fong-Ha; Mackay, Lindsey; Murby, John

2010-01-01

The CCQM-K69 key comparison of testosterone glucuronide in human urine was organized under the auspices of the CCQM Organic Analysis Working Group (OAWG). The National Measurement Institute Australia (NMIA) acted as the coordinating laboratory for the comparison. The samples distributed for the key comparison were prepared at NMIA with funding from the World Anti-Doping Agency (WADA). WADA granted the approval for this material to be used for the intercomparison provided the distribution and handling of the material were strictly controlled. Three national metrology institutes (NMIs)/designated institutes (DIs) developed reference methods and submitted data for the key comparison along with two other laboratories who participated in the parallel pilot study. A good selection of analytical methods and sample workup procedures was displayed in the results submitted considering the complexities of the matrix involved. The comparability of measurement results was successfully demonstrated by the participating NMIs. Only the key comparison data were used to estimate the key comparison reference value (KCRV), using the arithmetic mean approach. The reported expanded uncertainties for results ranged from 3.7% to 6.7% at the 95% level of confidence and all results agreed within the expanded uncertainty of the KCRV. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).

Pre-diagnostic Clinical Presentations and Medical History Prior to the Diagnosis of Inflammatory Bowel Disease in Children.

PubMed

Kwon, Yong Hoon; Kim, Yong Joo

2013-09-01

The clinical presentations of inflammatory bowel disease (IBD) prior to diagnosis are so diverse or vague that many of them waste time before final diagnosis. This study was undertaken to know the medical history of the pediatric patients until the final diagnosis could be reached. The medical records of all pediatric patients who were diagnosed with IBD (Crohn's disease [CD] in 14 children, ulcerative colitis [UC] in 17) during the last 13 years were reviewed. We investigated the length of the diagnostic time lag, chief clinical presentation, and any useful laboratory predictor among the routinely performed examinations. Indeterminate colitis was not included. The mean ages of children at the final diagnosis was similar in both diseases. As for the pre-clinical past history of bowel symptoms in CD patients, 5 were previously healthy, 9 had had 1-3 gastrointestinal (GI) symptoms, weight loss, bloody stool, anemia and rectal prolapse. With UC, 9 were previously healthy, 8 had had 1-3 GI symptoms, bloody stool, anorexia. The average diagnostic time lag with CD was 3.36 months, and with UC 2.2 months. Body mass index (BMI) and the initial basic laboratory data (white blood cell, hemoglobin, mean corpuscular volume, serum albumin, and serum total protein) were lower in CD, statistically significant only in BMI. IBD shows diverse clinical symptoms before its classical features, making the patients waste time until diagnosis. It is important to concern possibility of IBD even in the mildly sick children who do not show the characteristic symptoms of IBD.

Lawrence Livermore National Laboratory Pre-project Rare Plant and Wildlife Surveys For the Pit 7 Drainage Diversion and Groundwater Extraction and Treatment Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Paterson, L; Woollett, J

In January 2007, the Department of Energy (DOE) released the final Environmental Assessment for the Proposed Environmental Remediation at the Lawrence Livermore National Laboratory (LLNL) Site 300 Pit 7 Complex. At the same time, the Department of Toxic Substances Control (DTSC) released the final Negative Declaration and Initial Study covering the Pit 7 remediation. No substantial adverse effect on wildlife species of concern was anticipated from the project. However, it was proposed that wildlife surveys should be conducted prior to construction because species locations and breeding areas could potentially change by the time construction activities began. Although no known populationsmore » of rare or endangered/threatened plant species were known to occur within the project impact area at the time these documents were released, rare plants listed by the California Native Plant Society had been observed in the vicinity. As such, both DOE and DTSC proposed that plant surveys would be undertaken at the appropriate time of year to determine if rare plants would be impacted by project construction. This document provides the results of wildlife and rare plant surveys taken prior to the start of construction at the Pit 7 Complex.« less

In situ vitrification application to buried waste: Final report of intermediate field tests at Idaho National Engineering Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Callow, R.A.; Weidner, J.R.; Loehr, C.A.

This report describes two in situ vitrification field tests conducted on simulated buried waste pits during June and July 1990 at the Idaho National Engineering Laboratory. In situ vitrification, an emerging technology for in place conversion of contaminated soils into a durable glass and crystalline waste form, is being investigated as a potential remediation technology for buried waste. The overall objective of the two tests was to access the general suitability of the process to remediate waste structures representative of buried waste found at Idaho National Engineering Laboratory. In particular, these tests, as part of a treatability study, were designedmore » to provide essential information on the field performance of the process under conditions of significant combustible and metal wastes and to test a newly developed electrode feed technology. The tests were successfully completed, and the electrode feed technology successfully processed the high metal content waste. Test results indicate the process is a feasible technology for application to buried waste. 33 refs., 109 figs., 39 tabs.« less

KEY COMPARISON: Final Report on EUROMET.T-K3: Regional key comparison of the realisations of the ITS-90 from 83.8058 K to 692.677 K

NASA Astrophysics Data System (ADS)

Renaot, E.; Hermier, Y.; Valin, M.; Bonnier, G.

2007-01-01

This report presents the results of the EUROMET regional key comparison corresponding to CCT-K3 and covering the temperature range from 83.8058 K (triple point of Ar) to 692.77 K (freezing point of Zn). The comparison involved the six NMIs previously involved in CCT-K3 (BNM-INM/CNAM, SMU, IMGC, NMi-VSL, NPL, PTB) and 18 European national laboratories. The comparison was divided into five different loops coordinated by a co-pilot chosen among the laboratories having participated in the CCT-K3 comparison. BNM-INM/CNAM played the role of pilot in establishing the link between the five loops. In each loop, an artefact in the form of a standard platinum resistance thermometer (SPRT) was circulated among the participant laboratories. In order to have sufficient information about the possible drift of the SPRTs, the co-pilots have performed a calibration over the full temperature range at the beginning and at the end of the loop. Each participant laboratory carried out the measurements in agreement with the protocol. After initial measurements of R(tpw) and successful annealing treatment, each calibration consisted of three measurements of R(t) at each fixed point, in separate realizations. Each measurement was followed by a measurement of R(tpw). The order of fixed points was Zn, Sn, In, Ga, Hg, Ar, but if a fixed point was not available, it was omitted. Values of W(t), and their average value, were calculated. The results were reported to the co-pilot and BNM-INM/CNAM, with uncertainty budgets and other specified data. The results of the comparison were analysed by BNM-INM/CNAM. For the sake of clarity, the results are firstly presented loop by loop. In a second step a EUROMET Reference Value (ERV) taking into account the whole comparison was defined. In order to calculate this ERV advantage was taken of the presence of BNM-INM/CNAM in the five loops; the differences between each laboratory's results and BNM-INM's were considered. The participant laboratories decided during a Workshop organized by the pilot in Vienna in April 2005 to use as ERV the weighted mean rather than the simple mean. The differences (TLab - TERV) are presented with the associated uncertainties. Given that the protocol of the comparison contains a detailed description of how the uncertainties are to be calculated, the uncertainty budgets established by the participants seem consistent or, at least, homogeneous. The degrees of equivalence between the participating laboratories (in the same loop or in different loops) are given with their associated uncertainty. Finally, a method for establishing the bilateral equivalence between the participants in CCT-K3 and in EUROMET'T-K3 is proposed. It is recommend to use a group of 'linking laboratories' composed by the pilot and the co-pilots in order to link EUROMET.T-K3 to CCT-K3. The hypothesis is that the mean temperature of the pilot and co-pilot laboratories is the same in EUROMET.T-K3 as it was in CCT-K3. A specific analysis of the pilot's and co-pilot's results shows that even when the results given by one or several members of the 'linking laboratories' are not positioned in the same place as in EUROMET.T-K3 and CCT-K3 the mean calculated for the group is really reproducible. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCT, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).

A laboratory evaluation of modified asphalt : final report.

DOT National Transportation Integrated Search

1981-01-01

Quality aggregate availability in southern Louisiana has reached an alarmingly low level, while naturally occurring materials (sands) have been ignored due to their poor structural properties. Recent research reported by Chem-Crete Corporation indica...

U02 : heavy truck rollover characterization (phase-A) final report.

DOT National Transportation Integrated Search

2009-01-01

This Heavy Truck Rollover Characterization Program is a major research effort conducted by the National Transportation Research Center, Inc. (NTRCI) in partnership with Oak Ridge National Laboratory (ORNL), Michelin Americas Research Company (MARC), ...

GRAIL Final Resting Spot

NASA Image and Video Library

2012-12-13

These maps of Earth moon highlight the region where the twin spacecraft of NASA Gravity Recovery and Interior Laboratory GRAIL mission will impact on Dec. 17, marking the end of its successful endeavor to map the moon gravity.

Laboratory investigation of the use of volcanic ash in concrete : final report.

DOT National Transportation Integrated Search

2016-09-01

Supplementary cementitious materials (SCMs) are commonly used in KDOT concrete pavements and : bridge decks to improve strength and permeability characteristics. The supplementary cementitious materials : allowed under current KDOT specifications are...

Evaluation of concrete patching materials : final report.

DOT National Transportation Integrated Search

1985-01-01

The project evaluated numerous repairs on portland cement concrete pavements and bridge decks made with a number of laboratory accepted, proprietary patching materials and portland cement concrete mixtures of different designs. It was ascertained tha...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miller, G.L.

This data package satisfies the requirement for a format IV, final report. It is a follow-up to the 45-day safety screen report for tank AP-104. Evaporator candidate feed from tank 241-AP-104 (hereafter referred to as AP-104) was characterized for physical, inorganic, organic and radiochemical parameters by the Westinghouse Hanford Company, 222-S Laboratory, and by the Battelle Pacific Northwest National Laboratory (PNNL), Analytical Chemistry Laboratory (ACL) as directed by the Tank Sample and Analysis Plan (TSAP), References 1 through 4. Preliminary data in the form of summary analytical tables were provided to the project in advance of this final report tomore » enable early estimation of evaporator operational parameters, using the Predict modeling program. Laboratory analyses at ACL Laboratory was performed according to the TSAP. Analyses were performed at the 222-S Laboratory as defined and specified in the TSAP and the Laboratory`s Quality Assurance Plan, References 5 and 6. Any deviations from the instructions documented in the TSAP are discussed in this narrative and are supported with additional documentation. SAMPLING The TSAP, section 2, provided sampling information for waste samples collected from tank AP-104. The bottle-on-a-string method was used to collect liquid grab samples from the tank. Each glass sample bottle was amber, precleaned, and contained approximately 100 milliliters. Each bottle was closed with a teflon seal cap (or teflon septum for volatile organic analysis samples). Field blank samples were prepared by placing deionized water into sampling bottles, lowering the unclosed bottles into the riser for a period of time, retrieving them from the riser, and then closing the bottles with the same types of caps used for the tank samples. None of the samples were preserved by acidification. Upon receipt, the sample bottles destined for organic analyses were placed in a refrigerator. No attempt was made during sampling to assure the complete filling of the bottles so as to exclude all headspace. These actions were consistent with safety procedures, which attempt to limit personnel exposure to hazardous ionizing radiation.« less

Selecting automation for the clinical chemistry laboratory.

PubMed

Melanson, Stacy E F; Lindeman, Neal I; Jarolim, Petr

2007-07-01

Laboratory automation proposes to improve the quality and efficiency of laboratory operations, and may provide a solution to the quality demands and staff shortages faced by today's clinical laboratories. Several vendors offer automation systems in the United States, with both subtle and obvious differences. Arriving at a decision to automate, and the ensuing evaluation of available products, can be time-consuming and challenging. Although considerable discussion concerning the decision to automate has been published, relatively little attention has been paid to the process of evaluating and selecting automation systems. To outline a process for evaluating and selecting automation systems as a reference for laboratories contemplating laboratory automation. Our Clinical Chemistry Laboratory staff recently evaluated all major laboratory automation systems in the United States, with their respective chemistry and immunochemistry analyzers. Our experience is described and organized according to the selection process, the important considerations in clinical chemistry automation, decisions and implementation, and we give conclusions pertaining to this experience. Including the formation of a committee, workflow analysis, submitting a request for proposal, site visits, and making a final decision, the process of selecting chemistry automation took approximately 14 months. We outline important considerations in automation design, preanalytical processing, analyzer selection, postanalytical storage, and data management. Selecting clinical chemistry laboratory automation is a complex, time-consuming process. Laboratories considering laboratory automation may benefit from the concise overview and narrative and tabular suggestions provided.

Exxon Valdez oil spill. State/federal natural resource damage assessment. Impact of the oil spill on juvenile pink and chum salmon and their prey in critical nearshore habitats. Fish/shellfish study number 4. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1994-01-01

The objective of the study was to determine the impact of the Exxon Valdez oil spill on juvenile pink and chum salmon during their initial period of residency in nearshore marine habitats of western Prince William Sound. In oiled locations, both pink and chum salmon fry in the nearshore marine environment observations and laboratory experiments indicated that ingestion of whole oil or oil-contaminated prey was an important route of contamination.

Ketene Formation in Interstellar Ices: A Laboratory Study

NASA Technical Reports Server (NTRS)

Hudson, Reggie L.; Loeffler, Mark Josiah

2013-01-01

The formation of ketene (H2CCO, ethenone) in polar and apolar ices was studied with in situ 0.8 MeV proton irradiation, far-UVphotolysis, and infrared spectroscopic analyses at 10-20 K. Using isotopically enriched reagents, unequivocal evidencewas obtained for ketene synthesis in H2O-rich and CO2-rich ices, and several reaction products were identified. Results from scavenging experiments suggested that ketene was formed by free-radical pathways, as opposed to acid-base processes or redox reactions. Finally, we use our results to draw conclusions about the formation and stability of ketene in the interstellar medium.

FLUCTUATING JAUNDICE IN THE ADENOCARCINOMA OF THE AMPULLA OF VATER: a classic sign or an exception?

PubMed

Alves, José Roberto; Amico, Enio Campos; Souza, Dyego Leandro Bezerra de; Oliveira, Patrick Vanttinny Vieira de; Maranhão, Ícaro Godeiro de Oliveira

2015-01-01

Some authors consider the fluctuating jaundice as a classic sign of the adenocarcinoma of the ampulla of Vater. Assessing the frequency of fluctuating jaundice in their forms of its depiction in the patients with adenocarcinoma of the ampulla of Vater. Observational and retrospective study, conducted through analyses of medical records from patients subjected to pancreatic cephalic resections between February 2008 and July 2013. The pathological examination of the surgical specimen was positive to adenocarcinoma of the ampulla of Vater. Concepts and differences on clinical and laboratory fluctuating jaundice were standardized. It was subdivided into type A and type B laboratory fluctuating jaundice. Twenty patients were selected. One of them always remained anicteric, 11 patients developed progressive jaundice, 2 of them developed clinical and laboratory fluctuating jaundice, 5 presented only laboratory fluctuating jaundice and one did not present significant variations on total serum bilirubin levels. Among the seven patients with fluctuating jaundice, two were classified as type A, one as type B and four were not classified due to lack information. Finally, progressive jaundice was the prevailing presentation form in these patients (11 cases). This series of cases suggested that clinical fluctuating jaundice is a uncommon signal in adenocarcinoma of the ampulla of Vater.

Evolution of organic molecules under Mars-like UV radiation conditions in space and laboratory

NASA Astrophysics Data System (ADS)

Rouquette, L.; Stalport, F.; Cottin, H.; Coll, P.; Szopa, C.; Saiagh, K.; Poch, O.; Khalaf, D.; Chaput, D.; Grira, K.; Dequaire, T.

2017-09-01

The detection and identification of organic molecules at Mars are of prime importance, as some of these molecules are life precursors and components. While in situ planetary missions are searching for them, it is essential to understand how organic molecules evolve and are preserved at the surface of Mars. Indeed the harsh conditions of the environment of Mars such as ultraviolet (UV) radiation or oxidative processes could explain the low abundance and diversity of organic molecules detected by now [1]. In order to get a better understanding of the evolution of organic matter at the surface of Mars, we exposed organic molecules under a Mars-like UV radiation environment. Similar organic samples were exposed to the Sun radiation, outside the International Space Station (ISS), and under a UV lamp (martian pressure and temperature conditions) in the laboratory. In both experiments, organic molecules tend to photodegrade under Mars-like UV radiation. Minerals, depending on their nature, can protect or accelerate the degradation of organic molecules. For some molecules, new products, possibly photoresistant, seem to be produced. Finally, experimenting in space allow us to get close to in situ conditions and to validate our laboratory experiment while the laboratory experiment is essential to study the evolution of a large amount and diversity of organic molecules.

KEY COMPARISON: CCQM-K25: Determination of PCB congeners in sediment

NASA Astrophysics Data System (ADS)

Schantz, Michele; Wise, Stephen

2004-01-01

Polychlorinated biphenyls (PCBs) consist of 209 possible congeners depending on the substitution of the chlorine atoms around the biphenyl molecule. PCBs have been widely used as industrial fluids, flame retardants, diluents, hydraulic fluids, and dielectric fluids for capacitors and transformers. As a class of compounds, they are environmentally stable and tend to bioaccumulate. Of the 209 possible congeners, approximately 150 congeners have been reported in the environment. Congener-specific PCB methods, which are typically based on gas chromatography (GC) with electron capture detection (ECD) or mass spectrometric (MS) detection, are designed to measure selected priority congeners, but the congeners of interest change with the study and sponsoring agency. A pilot study (CCQM-P17) for the determination of PCB congeners in sediment was organized by NIST and NRC-Canada in 2000. Ten laboratories participated in the pilot study. After discussion and critical review of the data, there was agreement that the pilot study should be followed by a Key Comparison and that the Key Comparison Reference Value (KCRV) should be derived from isotope dilution GC/MS (ID-GC/MS) based methods that had been validated in the Pilot Study. The CCQM-K25 Key Comparison study utilized a sediment sample prepared by mixing known quantities of two sediment materials to simulate a moderately contaminated sample with respect to PCBs. Nine laboratories participated in CCQM-K25 and demonstrated a high level of equivalence in capabilities for determining five PCB congeners (congener numbers 28, 101, 105, 153, and 170) in a moderately contaminated sediment using GC/MS-based methods. The amount of substance concentration for the congeners measured ranged from ~10 ng/g to ~35 ng/g. The relative expanded uncertainties of the KCRVs ranged from 2% to 5%, indicating excellent agreement among the participants that used ID-GC/MS. Results from the one laboratory that used GC/MS with a non-labeled PCB congener as internal standard showed no systematic bias from the results of other laboratories. The five PCB congeners measured in CCQM-K25 were selected to be representative of the approximately 150 congeners found in environmental samples and to provide the typical analytical measurement challenges encountered in the measurement of individual congeners such as volatility losses during sample preparation and coelution during chromatographic separation. The abilities demonstrated by the laboratories that provided comparable measurements for all five congeners in this Key Comparison should be indicative of their ability to provide reference measurements for the typical suite of PCB congeners found in moderately contaminated sediments (individual congener amount of substance concentrations >5 ng/g dry basis). Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the Mutual Recognition Arrangement (MRA).

Clinical pharmacology quality assurance program: models for longitudinal analysis of antiretroviral proficiency testing for international laboratories.

PubMed

DiFrancesco, Robin; Rosenkranz, Susan L; Taylor, Charlene R; Pande, Poonam G; Siminski, Suzanne M; Jenny, Richard W; Morse, Gene D

2013-10-01

Among National Institutes of Health HIV Research Networks conducting multicenter trials, samples from protocols that span several years are analyzed at multiple clinical pharmacology laboratories (CPLs) for multiple antiretrovirals. Drug assay data are, in turn, entered into study-specific data sets that are used for pharmacokinetic analyses, merged to conduct cross-protocol pharmacokinetic analysis, and integrated with pharmacogenomics research to investigate pharmacokinetic-pharmacogenetic associations. The CPLs participate in a semiannual proficiency testing (PT) program implemented by the Clinical Pharmacology Quality Assurance program. Using results from multiple PT rounds, longitudinal analyses of recovery are reflective of accuracy and precision within/across laboratories. The objectives of this longitudinal analysis of PT across multiple CPLs were to develop and test statistical models that longitudinally: (1) assess the precision and accuracy of concentrations reported by individual CPLs and (2) determine factors associated with round-specific and long-term assay accuracy, precision, and bias using a new regression model. A measure of absolute recovery is explored as a simultaneous measure of accuracy and precision. Overall, the analysis outcomes assured 97% accuracy (±20% of the final target concentration of all (21) drug concentration results reported for clinical trial samples by multiple CPLs). Using the Clinical Laboratory Improvement Act acceptance of meeting criteria for ≥2/3 consecutive rounds, all 10 laboratories that participated in 3 or more rounds per analyte maintained Clinical Laboratory Improvement Act proficiency. Significant associations were present between magnitude of error and CPL (Kruskal-Wallis P < 0.001) and antiretroviral (Kruskal-Wallis P < 0.001).

[The "Instituto de Salud Carlos III" and the public health in Spain. Origin of laboratory medicine and of the central laboratories and research in public health].

PubMed

Nájera Morrondo, Rafael

2006-01-01

The "Instituto de Salud Carlos III" is the Central Public Health Laboratory in Spain with an important component of scientific research in health related areas, such as cancer, cardiovascular diseases, infectious diseases and environmental health. The article describes the development of the Public Health Institutes. arising from the introduction and development of scientific and laboratory based medicine and the introduction of vaccination and sanitation with the control of water and food. At about the same time, the discoveries in microbiology and immunology were produced, being the research activities incardinated with the practical advances in the control of products. To cope with the practical needs, Institutions were created with the responsibility of providing smallpox vaccine but incorporating very soon production of sera and other vaccines and water and sanitation control and foods control. At the same time. colonization of countries specially in Africa, South East Asia and explorations in Central America confront the Europeans with new diseases and the need of laboratories where to study them. These circumstances gave rise to the birth of the Central Public Health Laboratories and the National institutes of Health at the beginning of the XX century in many countries. In Spain, the Spanish Civil War was a breaking point in the development of such an institution that finally was reinvented with the creation of the Instituto de Salud Carlos III, in 1986, incorporating research and epidemiological surveillance and control of diseases and also the responsibilities of the Food and Drug Control, lately separated from it.

C-B3-03: Development and Pilot Testing of Guidelines to Monitor High-Risk Medications in the Ambulatory Setting

PubMed Central

Tjia, Jennifer; Field, Terry; Garber, Lawrence; Raebel, Marsha; Donovan, Jennifer; Kanaan, Abir; Fischer, Shira; Gagne, Shawn; Zhao, Yanfang; Fuller, Jackie; Gurwitz, Jerry

2010-01-01

Background: Inadequate laboratory monitoring of high-risk medications contributes to preventable adverse drug events. One barrier to appropriate monitoring is lack of standardized monitoring guidelines. The study aims were to develop guidelines to monitor high-risk medications and to assess the prevalence of laboratory testing for these medications in a multispecialty group practice. Methods: We developed guidelines for laboratory monitoring of high-risk medications as part of a patient safety intervention trial. An advisory committee of national experts and local leaders (clinicians, pharmacists, pharmacoepidemiologists, and patient safety experts) used a two-round, internet-based Delphi process to select guideline medications based on the importance of monitoring for efficacy, safety, and drug-drug interactions. Test frequency recommendations were developed by academic pharmacists based on literature review and local interdisciplinary consensus. To estimate the potential impact of the intervention, we determined the prevalence of high-risk drug dispensings and laboratory testing for guideline medications between January 1, 2008 and July 31, 2008. Results: Consensus on medications to include in the guidelines was achieved in two rounds. Final guidelines included 35 drugs/drug classes and 61 laboratory tests. The prevalence of monitoring ranged from <50% to >90%, with infrequently prescribed drugs having a lower prevalence of recommended testing. When more than one test was recommended for a selected medication, monitoring within a medication sometimes differed by > 50%. Conclusions: Even among drugs where there is general consensus that laboratory monitoring is important, prevalence of monitoring is highly variable. Further, infrequently prescribed medications are at higher risk for poor monitoring.

Economic analysis of Darrieus vertical axis wind turbine systems for the generation of utility grid electrical power. Volume IV. Summary and analysis of the A. T. Kearney and Alcoa Laboratories point design economic studies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sullivan, W.N.; Nellums, R.O.

1979-08-01

The A.T. Kearney and Alcoa economic studies are two independent attempts to assess the installed costs of a series of six Darrieus vertical axis wind turbine designs. The designs cover a range of sizes with peak outputs from 10 to 1600 kW. All are designed to produce utility grid electrical power. Volume IV of this report summarizes, compares, and analyzes the results of these studies. The Kearney and Alcoa final reports are included in the Appendices.

Economic analysis of Darrieus vertical axis wind turbine systems for the generation of utility grid electrical power. Volume IV: summary and analysis of the A. T. Kearney and Alcoa Laboratories point design economic studies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sullivan, W.N.; Nellums, R.O.

1979-08-01

The A. T. Kearney and Alcoa economic studies are two independent attempts to assess the installed costs of a series of six Darrieus vertical axis wind turbine designs. The designs cover a range of sizes with peak outputs from 10 to 1600 kW. All are designed to produce utility grid electrical power. Volume IV of this report summarizes, compares, and analyzes the results of these studies. The Kearney and Alcoa final reports are included in the Appendices.

Study of Isospin Correlation in High Energy Heavy Ion Interactions with the RHIC PHENIX. Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Takahashi, Y.

This report describes the research work performed under the support of the DOE research grant E-FG02-97ER4108. The work is composed of three parts: (1) Visual analysis and quality control of the Micro Vertex Detector (MVD) of the PHENIX experiments carried out of Brookhaven National Laboratory. (2) Continuation of the data analysis of the EMU05/09/16 experiments for the study of the inclusive particle production spectra and multi-particle correlation. (3) Exploration of a new statistical means to study very high-multiplicity of nuclear-particle ensembles and its perspectives to apply to the higher energy experiments.

Calculation of the compounded uncertainty of 14C AMS measurements

NASA Astrophysics Data System (ADS)

Nadeau, Marie-Josée; Grootes, Pieter M.

2013-01-01

The correct method to calculate conventional 14C ages from the carbon isotopic ratios was summarised 35 years ago by Stuiver and Polach (1977) and is now accepted as the only method to calculate 14C ages. There is, however, no consensus regarding the treatment of AMS data, mainly of the uncertainty of the final result. The estimation and treatment of machine background, process blank, and/or in situ contamination is not uniform between laboratories, leading to differences in 14C results, mainly for older ages. As Donahue (1987) and Currie (1994), among others, mentioned, some laboratories find it important to use the scatter of several measurements as uncertainty while others prefer to use Poisson statistics. The contribution of the scatter of the standards, machine background, process blank, and in situ contamination to the uncertainty of the final 14C result is also treated in different ways. In the early years of AMS, several laboratories found it important to describe their calculation process in details. In recent years, this practise has declined. We present an overview of the calculation process for 14C AMS measurements looking at calculation practises published from the beginning of AMS until present.

Clinical laboratory: bigger is not always better.

PubMed

Plebani, Mario

2018-06-27

Laboratory services around the world are undergoing substantial consolidation and changes through mechanisms ranging from mergers, acquisitions and outsourcing, primarily based on expectations to improve efficiency, increasing volumes and reducing the cost per test. However, the relationship between volume and costs is not linear and numerous variables influence the end cost per test. In particular, the relationship between volumes and costs does not span the entire platter of clinical laboratories: high costs are associated with low volumes up to a threshold of 1 million test per year. Over this threshold, there is no linear association between volumes and costs, as laboratory organization rather than test volume more significantly affects the final costs. Currently, data on laboratory errors and associated diagnostic errors and risk for patient harm emphasize the need for a paradigmatic shift: from a focus on volumes and efficiency to a patient-centered vision restoring the nature of laboratory services as an integral part of the diagnostic and therapy process. Process and outcome quality indicators are effective tools to measure and improve laboratory services, by stimulating a competition based on intra- and extra-analytical performance specifications, intermediate outcomes and customer satisfaction. Rather than competing with economic value, clinical laboratories should adopt a strategy based on a set of harmonized quality indicators and performance specifications, active laboratory stewardship, and improved patient safety.

Current Pre- and Post-Graduate Vocational Education and Training in Laboratory Medicine and Microbiology in Poland

PubMed Central

Owczarek, Henryk

2010-01-01

The status of Polish medical laboratories in continuously changing. Since 2001 the legal framework was established for the clinical chemists employed in medical and microbiological laboratories. Since that time, the job performance by clinical chemists is limited only to the specialist, member of the Polish Chamber of Laboratory Diagnosticians. According to that legal act, graduate in laboratory medicine is certified to perform the professional activities in medical or microbiological laboratories without further vocational training. After graduating from biology, chemistry, pharmacy or veterinary medicine, a person can perform the job only under supervision of a certified clinical chemist. Several Medical Universities have organized the system of post-graduation education for such graduates. The main courses taught are basic pathology, internal medicine, hematology, immunology, and clinical chemistry. In addition, the Ministry of Health and Chamber of Laboratory Diagnosticians are organizing and supervising the higher level of post-graduate education for clinical chemists, the education and vocational training which leads to the title of specialist in clinical chemistry or similar area in laboratory medicine. The professional qualification of such person are evaluated during the final exam at the national level. The specialist is eligible to act as director of clinical laboratories. PMID:27683359

Microbial ranking of porous packaging materials (exposure chamber method), ASTM method: collaborative study.

PubMed

Placencia, A M; Peeler, J T

1999-01-01

A collaborative study involving 11 laboratories was conducted to measure the microbial barrier effectiveness of porous medical packaging. Two randomly cut samples from each of 6 commercially available porous materials and one positive and one negative control were tested by one operator in each of 11 laboratories. Microbial barrier effectiveness was measured in terms of logarithm reduction value (LRV), which reflects the log10 microbial penetration of the material being tested. The logarithm of the final concentration is subtracted from that of the initial concentration to obtain the LRV. Thus the higher the LRV, the better the barrier. Repeatability standard deviations ranged from 6.42 to 16.40; reproducibility standard deviations ranged from 15.50 to 22.70. Materials B(53), C(50), D(CT), and E(45MF) differ significantly from the positive control. The microbial ranking of porous packaging materials (exposure chamber method), ASTM method, has been adopted First Action by AOAC INTERNATIONAL.