Sample records for large diameter head

  1. High Revision Rate for Large-head Metal-on-metal THA at a Mean of 7.1 Years: A Registry Study.

    PubMed

    Seppänen, Matti; Laaksonen, Inari; Pulkkinen, Pekka; Eskelinen, Antti; Puhto, Ari-Pekka; Kettunen, Jukka; Leskinen, Jarkko; Manninen, Mikko; Mäkelä, Keijo

    2018-06-01

    Large-diameter head metal-on-metal (MoM) THA has largely been abandoned as a result of higher than anticipated revision rates. However, the majority of these implants are still in situ. Although earlier reports from the Finnish Arthroplasty Register noted similar short-term survivorship between large-diameter head MoM THA and conventional cemented THA, longer term survivorship of this population is unclear. Although reported revision rates for this implant group have been high, the majority of these implants have not been revised and followup is important to improve long-term management. The purposes of this study were (1) to compare the 10-year competing risk survivorship of large-diameter head MoM THA with the survivorship of conventional THA in the Finnish Arthroplasty Register; (2) to report the large-diameter head MoM THA survival at the manufacturer/brand level; and (3) to identify the most common reasons for revision of large-diameter head MoM THA in the Finnish Arthroplasty Register. The six most commonly used large-diameter head (≥ 38 mm) MoM THA devices in Finland between years 2004 and 2013 were selected (n = 10,959 implants). The completeness of the Finnish Registry is > 95% in primary THA and patients are censored from the date of death or at the point of emigration; followup continued until the end of 2015. The conventional THA control group consisted of the two most frequently used devices (Vision/Bimetric and ABG II/ABG II) with metal-on-polyethylene or ceramic-on-ceramic bearing surfaces implanted between 2002 and 2013 (n = 5177). The study group was formed by selecting all pairs of large-diameter head MoM and reference THA protheses within the same age group ( < 49, 50-54, 55-59, 60-64, 65-69, 70-74, and 75+ years), sex, diagnosis (osteoarthritis, other), and hospital yearly operation count (< 100 operations yearly, ≥ 100 operations yearly); 5166 matched pairs were identified. Revision for any reason was considered as the failure endpoint of followup. Implant survival (the proportion not revised) was calculated from corresponding cumulative incidence function adjusted for patient death as a competing event for revision. Large-diameter head MoM implant group revision hazard ratios with 95% confidence intervals were estimated with age group, sex, diagnosis, and hospital yearly operation count as confounding factors in a Cox regression model. Ten-year survivorship free from all-cause revision was lower for THAs that used a large-diameter femoral head than it was for the control group of conventional THA (83% [95% confidence interval {CI}, 82%-84%] versus 92% [95% CI, 91%-93%]). At the implant level, every large-diameter head MoM THA had a higher risk for revision compared with the conventional THA control group from the fourth postoperative year onward. The highest survival of MoM THA was 88% (95% CI, 86%-90%) for the ReCap/Bimetric and the lowest survival was 46% (95% CI, 41%-51%) for the recalled ASR with either the Summit® or Corail® stem. The most common revision reason in the MoM THA group was adverse reaction to metal debris, whereas dislocation was predominant in the conventional THA control group. The revision rate for all large-diameter head MoM THAs in this timeframe in the Finnish Arthroplasty Register is unacceptably high and in our view supports the decision to abandon their use. In agreement with the directives of other national organizations, we recommend regular followup of all patients with large-diameter head MoM THA. Based on our results, strict guidelines for followup should be maintained over the lifetime of the implant to assess patient symptoms and recommend revision when indicated. Level III, therapeutic study.

  2. Does Choice of Head Size and Neck Geometry Affect Stem Migration in Modular Large-Diameter Metal-on-Metal Total Hip Arthroplasty? A Preliminary Analysis

    PubMed Central

    Georgiou, CS; Evangelou, KG; Theodorou, EG; Provatidis, CG; Megas, PD

    2012-01-01

    Due to their theoretical advantages, hip systems combining modular necks and large diameter femoral heads have gradually gained popularity. However, among others, concerns regarding changes in the load transfer patterns were raised. Recent stress analyses have indeed shown that the use of modular necks and big femoral heads causes significant changes in the strain distribution along the femur. Our original hypothesis was that these changes may affect early distal migration of a modular stem. We examined the effect of head diameter and neck geometry on migration at two years of follow-up in a case series of 116 patients (125 hips), who have undergone primary Metal-on-Metal total hip arthroplasty with the modular grit-blasted Profemur®E stem combined with large-diameter heads (>36 mm). We found that choice of neck geometry and head diameter has no effect on stem migration. A multivariate regression analysis including the potential confounding variables of the body mass index, bone quality, canal fill and stem positioning revealed only a negative correlation between subsidence and canal fill in midstem area. Statistical analysis, despite its limitations, did not confirm our hypothesis that choice of neck geometry and/or head diameter affects early distal migration of a modular stem. However, the importance of correct stem sizing was revealed. PMID:23284597

  3. Does Choice of Head Size and Neck Geometry Affect Stem Migration in Modular Large-Diameter Metal-on-Metal Total Hip Arthroplasty? A Preliminary Analysis.

    PubMed

    Georgiou, Cs; Evangelou, Kg; Theodorou, Eg; Provatidis, Cg; Megas, Pd

    2012-01-01

    Due to their theoretical advantages, hip systems combining modular necks and large diameter femoral heads have gradually gained popularity. However, among others, concerns regarding changes in the load transfer patterns were raised. Recent stress analyses have indeed shown that the use of modular necks and big femoral heads causes significant changes in the strain distribution along the femur. Our original hypothesis was that these changes may affect early distal migration of a modular stem. We examined the effect of head diameter and neck geometry on migration at two years of follow-up in a case series of 116 patients (125 hips), who have undergone primary Metal-on-Metal total hip arthroplasty with the modular grit-blasted Profemur®E stem combined with large-diameter heads (>36 mm). We found that choice of neck geometry and head diameter has no effect on stem migration. A multivariate regression analysis including the potential confounding variables of the body mass index, bone quality, canal fill and stem positioning revealed only a negative correlation between subsidence and canal fill in midstem area. Statistical analysis, despite its limitations, did not confirm our hypothesis that choice of neck geometry and/or head diameter affects early distal migration of a modular stem. However, the importance of correct stem sizing was revealed.

  4. [Are Higher Prices for Larger Femoral Heads in Total Hip Arthroplasty Justified from the Perspective of Health Care Economics? An Analysis of Costs and Effects in Germany].

    PubMed

    Grunert, R; Schleifenbaum, S; Möbius, R; Sommer, G; Zajonz, D; Hammer, N; Prietzel, T

    2017-02-01

    Background: In total hip arthroplasty (THA), femoral head diameter has not been regarded as a key parameter which should be restored when reconstructing joint biomechanics and geometry. Apart from the controversial discussion on the advantages and disadvantages of using larger diameter heads, their higher cost is another important reason that they have only been used to a limited extent. The goal of this study was to analyse the price structure of prosthetic heads in comparison to other components used in THA. A large group of patients with hip endoprostheses were evaluated with respect to the implanted socket diameter and thus the theoretically attainable head diameter. Materials and Methods: The relative prices of various THA components (cups, inserts, stems and ball heads) distributed by two leading German manufacturers were determined and analysed. Special attention was paid to different sizes and varieties in a series of components. A large patient population treated with THA was evaluated with respect to the implanted cup diameter and therefore the theoretically attainable head diameter. Results: The pricing analysis of the THA components of two manufacturers showed identical prices for cups, inserts and stems in a series. In contrast to this, the prices for prosthetic heads with a diameter of 36-44 mm were 11-50 % higher than for 28 mm heads. Identical prices for larger heads were the exception. The distribution of the head diameter in 2719 THA cases showed significant differences between the actually implanted and the theoretically attainable heads. Conclusion: There are proven advantages in using larger diameter ball heads in THA and the remaining problems can be solved. It is therefore desirable to correct the current pricing practice of charging higher prices for larger components. Instead, identical prices should be charged for all head diameters in a series, as is currently established practice for all other THA components. Thus when reconstructing biomechanics and joint geometry in THA, it should be possible to recover not only leg length, femoral offset and antetorsion of the femoral neck, but also to approximately restore the diameter of the femoral head and thereby optimise the functional outcome. Georg Thieme Verlag KG Stuttgart · New York.

  5. Research on the magnetorheological finishing (MRF) technology with dual polishing heads

    NASA Astrophysics Data System (ADS)

    Huang, Wen; Zhang, Yunfei; He, Jianguo; Zheng, Yongcheng; Luo, Qing; Hou, Jing; Yuan, Zhigang

    2014-08-01

    Magnetorheological finishing (MRF) is a key polishing technique capable of rapidly converging to the required surface figure. Due to the deficiency of general one-polishing-head MRF technology, a dual polishing heads MRF technology was studied and a dual polishing heads MRF machine with 8 axes was developed. The machine has the ability to manufacture large aperture optics with high figure accuracy. The large polishing head is suitable for polishing large aperture optics, controlling large spatial length's wave structures, correcting low-medium frequency errors with high removal rates. While the small polishing head has more advantages in manufacturing small aperture optics, controlling small spatial wavelength's wave structures, correcting mid-high frequency and removing nanoscale materials. Material removal characteristic and figure correction ability for each of large and small polishing head was studied. Each of two polishing heads respectively acquired stable and valid polishing removal function and ultra-precision flat sample. After a single polishing iteration using small polishing head, the figure error in 45mm diameter of a 50 mm diameter plano optics was significantly improved from 0.21λ to 0.08λ by PV (RMS 0.053λ to 0.015λ). After three polishing iterations using large polishing head , the figure error in 410mm×410mm of a 430mm×430mm large plano optics was significantly improved from 0.40λ to 0.10λ by PV (RMS 0.068λ to 0.013λ) .This results show that the dual polishing heads MRF machine not only have good material removal stability, but also excellent figure correction capability.

  6. Raised levels of metal ions in the blood in patients who have undergone uncemented metal-on-polyethylene Trident-Accolade total hip replacement.

    PubMed

    Craig, P; Bancroft, G; Burton, A; Collier, S; Shaylor, P; Sinha, A

    2014-01-01

    The issues surrounding raised levels of metal ions in the blood following large head metal-on-metal total hip replacement (THR), such as cobalt and chromium, have been well documented. Despite the national popularity of uncemented metal-on-polyethylene (MoP) THR using a large-diameter femoral head, few papers have reported the levels of metal ions in the blood following this combination. Following an isolated failure of a 44 mm Trident-Accolade uncemented THR associated with severe wear between the femoral head and the trunnion in the presence of markedly elevated levels of cobalt ions in the blood, we investigated the relationship between modular femoral head diameter and the levels of cobalt and chromium ions in the blood following this THR. A total of 69 patients received an uncemented Trident-Accolade MoP THR in 2009. Of these, 43 patients (23 men and 20 women, mean age 67.0 years) were recruited and had levels of cobalt and chromium ions in the blood measured between May and June 2012. The patients were then divided into three groups according to the diameter of the femoral head used: 12 patients in the 28 mm group (controls), 18 patients in the 36 mm group and 13 patients in the 40 mm group. A total of four patients had identical bilateral prostheses in situ at phlebotomy: one each in the 28 mm and 36 mm groups and two in the 40 mm group. There was a significant increase in the mean levels of cobalt ions in the blood in those with a 36 mm diameter femoral head compared with those with a 28 mm diameter head (p = 0.013). The levels of cobalt ions in the blood were raised in those with a 40 mm diameter head but there was no statistically significant difference between this group and the control group (p = 0.152). The levels of chromium ions in the blood were normal in all patients. The clinical significance of this finding is unclear, but we have stopped using femoral heads with a diameter of ≤ 36 mm, and await further larger studies to clarify whether, for instance, this issue particularly affects this combination of components.

  7. Birmingham Mid-Head Resection hip arthroplasty in a young man with gigantism.

    PubMed

    Murphy, Michael T; Shillington, Mark P; Mogridge, Damon R; Journeaux, Simon F

    2012-02-01

    The Birmingham Mid-Head Resection (Smith & Nephew Ltd, Warwick, United Kingdom) arthroplasty is a new bone-conserving procedure that, like hip resurfacing, is used in younger, active patients. We present the case of a young man with Sotos syndrome (cerebral gigantism) with associated extraordinary stature (height, 2.16 m; weight, 157 kg) who underwent Birmingham Mid-Head Resection arthroplasty. The large stature of this patient required a custom manufactured prosthesis (a femoral head 68 mm in diameter with an acetabular cup 76 mm in diameter). We believe this to be the largest metal-on-metal resurfacing articulation and hip arthroplasty reported to date. Copyright © 2012 Elsevier Inc. All rights reserved.

  8. Large Diameter Femoral Heads Impose Significant Alterations on the Strains Developed on Femoral Component and Bone: A Finite Element Analysis

    PubMed Central

    Theodorou, E.G; Provatidis, C.G; Babis, G.C; Georgiou, C.S; Megas, P.D

    2011-01-01

    Total Hip Arthroplasty aims at fully recreating a functional hip joint. Over the past years modular implant systems have become common practice and are widely used, due to the surgical options they provide. In addition Big Femoral Heads have also been implemented in the process, providing more flexibility for the surgeon. The current study aims at investigating the effects that femoral heads of bigger diameter may impose on the mechanical behavior of the bone-implant assembly. Using data acquired by Computed Tomographies and a Coordinate Measurement Machine, a cadaveric femur and a Profemur-E modular stem were fully digitized, leading to a three dimensional finite element model in ANSYS Workbench. Strains and stresses were then calculated, focusing on areas of clinical interest, based on Gruen zones: the calcar and the corresponding below the greater trochanter area in the proximal femur, the stem tip region and a profile line along linea aspera. The performed finite elements analysis revealed that the use of large diameter heads produces significant changes in strain development within the bone volume, especially in the lateral side. The application of Frost’s law in bone remodeling, validated the hypothesis that for all diameters normal bone growth occurs. However, in the calcar area lower strain values were recorded, when comparing with the reference model featuring a 28mm femoral head. Along line aspera and for the stem tip area, higher values were recorded. Finally, stresses calculated on the modular neck revealed increased values, but without reaching the yield strength of the titanium alloy used. PMID:21792381

  9. Large diameter femoral heads impose significant alterations on the strains developed on femoral component and bone: a finite element analysis.

    PubMed

    Theodorou, E G; Provatidis, C G; Babis, G C; Georgiou, C S; Megas, P D

    2011-01-01

    Total Hip Arthroplasty aims at fully recreating a functional hip joint. Over the past years modular implant systems have become common practice and are widely used, due to the surgical options they provide. In addition Big Femoral Heads have also been implemented in the process, providing more flexibility for the surgeon. The current study aims at investigating the effects that femoral heads of bigger diameter may impose on the mechanical behavior of the bone-implant assembly. Using data acquired by Computed Tomographies and a Coordinate Measurement Machine, a cadaveric femur and a Profemur-E modular stem were fully digitized, leading to a three dimensional finite element model in ANSYS Workbench. Strains and stresses were then calculated, focusing on areas of clinical interest, based on Gruen zones: the calcar and the corresponding below the greater trochanter area in the proximal femur, the stem tip region and a profile line along linea aspera. The performed finite elements analysis revealed that the use of large diameter heads produces significant changes in strain development within the bone volume, especially in the lateral side. The application of Frost's law in bone remodeling, validated the hypothesis that for all diameters normal bone growth occurs. However, in the calcar area lower strain values were recorded, when comparing with the reference model featuring a 28mm femoral head. Along line aspera and for the stem tip area, higher values were recorded. Finally, stresses calculated on the modular neck revealed increased values, but without reaching the yield strength of the titanium alloy used.

  10. System for producing a uniform rubble bed for in situ processes

    DOEpatents

    Galloway, T.R.

    1983-07-05

    A method and a cutter are disclosed for producing a large cavity filled with a uniform bed of rubblized oil shale or other material, for in situ processing. A raise drill head has a hollow body with a generally circular base and sloping upper surface. A hollow shaft extends from the hollow body. Cutter teeth are mounted on the upper surface of the body and relatively small holes are formed in the body between the cutter teeth. Relatively large peripheral flutes around the body allow material to drop below the drill head. A pilot hole is drilled into the oil shale deposit. The pilot hole is reamed into a large diameter hole by means of a large diameter raise drill head or cutter to produce a cavity filled with rubble. A flushing fluid, such as air, is circulated through the pilot hole during the reaming operation to remove fines through the raise drill, thereby removing sufficient material to create sufficient void space, and allowing the larger particles to fill the cavity and provide a uniform bed of rubblized oil shale. 4 figs.

  11. Multiple Small Diameter Drillings Increase Femoral Neck Stability Compared with Single Large Diameter Femoral Head Core Decompression Technique for Avascular Necrosis of the Femoral Head.

    PubMed

    Brown, Philip J; Mannava, Sandeep; Seyler, Thorsten M; Plate, Johannes F; Van Sikes, Charles; Stitzel, Joel D; Lang, Jason E

    2016-10-26

    Femoral head core decompression is an efficacious joint-preserving procedure for treatment of early stage avascular necrosis. However, postoperative fractures have been described which may be related to the decompression technique used. Femoral head decompressions were performed on 12 matched human cadaveric femora comparing large 8mm single bore versus multiple 3mm small drilling techniques. Ultimate failure strength of the femora was tested using a servo-hydraulic material testing system. Ultimate load to failure was compared between the different decompression techniques using two paired ANCOVA linear regression models. Prior to biomechanical testing and after the intervention, volumetric bone mineral density was determined using quantitative computed tomography to account for variation between cadaveric samples and to assess the amount of bone disruption by the core decompression. Core decompression, using the small diameter bore and multiple drilling technique, withstood significantly greater load prior to failure compared with the single large bore technique after adjustment for bone mineral density (p< 0.05). The 8mm single bore technique removed a significantly larger volume of bone compared to the 3mm multiple drilling technique (p< 0.001). However, total fracture energy was similar between the two core decompression techniques. When considering core decompression for the treatment of early stage avascular necrosis, the multiple small bore technique removed less bone volume, thereby potentially leading to higher load to failure.

  12. Large Metal Heads and Vitamin E Polyethylene Increase Frictional Torque in Total Hip Arthroplasty.

    PubMed

    Meneghini, R Michael; Lovro, Luke R; Wallace, Joseph M; Ziemba-Davis, Mary

    2016-03-01

    Trunnionosis has reemerged in modern total hip arthroplasty for reasons that remain unclear. Bearing frictional torque transmits forces to the modular head-neck interface, which may contribute to taper corrosion. The purpose of this study is to compare frictional torque of modern bearing couples in total hip arthroplasty. Mechanical testing based on in vivo loading conditions was used to measure frictional torque. All bearing couples were lubricated and tested at 1 Hz for more than 2000 cycles. The bearing couples tested included conventional, highly crosslinked (XLPE) and vitamin E polyethylene, CoCr, and ceramic femoral heads and dual-mobility bearings. Statistical analysis was performed using Student t test for single-variable and analysis of variance for multivariant analysis. P ≤ .05 was considered statistically significant. Large CoCr metal heads (≥36 mm) substantially increased frictional torque against XLPE liners (P = .01), a finding not observed in ceramic heads. Vitamin E polyethylene substantially increased frictional torque compared with XLPE in CoCr and ceramic heads (P = .001), whereas a difference between conventional and XLPE was not observed (P = .69) with the numbers available. Dual-mobility bearing with ceramic inner head demonstrated the lowest mean frictional torque of all bearing couples. In this simulated in vivo model, large-diameter CoCr femoral heads and vitamin E polyethylene liners are associated with increased frictional torque compared with smaller metal heads and XLPE, respectively. The increased frictional torque of vitamin E polyethylene and larger-diameter femoral heads should be considered and further studied, along with reported benefits of these modern bearing couples. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. Adverse Reactions to Metal on Metal Are Not Exclusive to Large Heads in Total Hip Arthroplasty.

    PubMed

    Lombardi, Adolph V; Berend, Keith R; Adams, Joanne B; Satterwhite, Keri L

    2016-02-01

    There is some suggestion that smaller diameter heads in metal-on-metal total hip arthroplasty (MoM THA) may be less prone to the adverse reactions to metal debris (ARMD) seen with large-diameter heads. We reviewed our population of patients with small head (≤ 32 mm) MoM THA to determine (1) the frequency of ARMD; (2) potential risk factors for ARMD in this population; and (3) the etiology of revision and Kaplan-Meier survivorship with revision for all causes. Small-diameter head MoM devices were used in 9% (347 of 3753) of primary THAs during the study period (January 1996 to March 2005). We generally used these implants in younger, more active, higher-demand patients. Three hundred hips (258 patients) had MoM THA using a titanium modular acetabular component with a cobalt-chromium tapered insert and were available for review with minimum 2-year followup (mean, 10 years; range, 2-19 years). Complete followup was available in 86% of hips (300 of 347). Clinical records and radiographs were reviewed to determine the frequency and etiology of revision. Kaplan-Meier survivorship analysis was performed. ARMD frequency was 5% (14 of 300 hips) and represented 70% (14 of 20) of revisions performed. Using multivariate analysis, no variable tested, including height, weight, body mass index, age, cup diameter, cup angle, use of screws, stem diameter, stem type, head diameter, preoperative clinical score, diagnosis, activity level, or sex, was significant as a risk factor for revision. Twenty hips have been revised: two for infection, four for aseptic loosening, and 14 for ARMD. Kaplan-Meier analysis revealed survival free of component revision for all causes was 95% at 10 years (95% confidence interval [CI], 91%-97%), 92% at 15 years (95% CI, 87%-95%), and 72% at 19 years (95% CI, 43%-90%), and survival free of component revision for aseptic causes was 96% at 10 years (95% CI, 92%-98%), 92% at 15 years (95% CI, 88%-95%), and 73% at 19 years (95% CI, 43%-90%). The late onset and devastating nature of metal-related failures is concerning with this small-diameter MoM device. Although the liner is modular, it cannot be exchanged and full acetabular revision is required. Patients with all MoM THA devices should be encouraged to return for clinical and radiographic followup, and clinicians should maintain a low threshold to perform a systematic evaluation. Symptomatic patients should undergo thorough investigation and vigilant observation for ARMD. Level IV, therapeutic study.

  14. System for producing a uniform rubble bed for in situ processes

    DOEpatents

    Galloway, Terry R.

    1983-01-01

    A method and a cutter for producing a large cavity filled with a uniform bed of rubblized oil shale or other material, for in situ processing. A raise drill head (72) has a hollow body (76) with a generally circular base and sloping upper surface. A hollow shaft (74) extends from the hollow body (76). Cutter teeth (78) are mounted on the upper surface of the body (76) and relatively small holes (77) are formed in the body (76) between the cutter teeth (78). Relatively large peripheral flutes (80) around the body (76) allow material to drop below the drill head (72). A pilot hole is drilled into the oil shale deposit. The pilot hole is reamed into a large diameter hole by means of a large diameter raise drill head or cutter to produce a cavity filled with rubble. A flushing fluid, such as air, is circulated through the pilot hole during the reaming operation to remove fines through the raise drill, thereby removing sufficient material to create sufficient void space, and allowing the larger particles to fill the cavity and provide a uniform bed of rubblized oil shale.

  15. Minimization of skin incisions at stripping by Mayo of large-diameter veins.

    PubMed

    Tsukanov, Yu

    2018-03-15

    To study the possibility of minimization of the skin incisions up to a puncture size at stripping by Mayo with the use of the stripper with an oval-ring head for large-diameter veins. The problem is solved due to the geometrical changing of the stripper head from a round to an oval one. The laboratory experiment showed that with a vein diameter of 10-20 mm the total cross-sectional area of its walls constituted 13.61 mm2, with a diameter of more than 20 mm it was 19.98 mm2. There were designed three types of the external dimensions for the stripper: 3.0 х 6.0 mm; 3,5 х 7.0 mm and 4.0 х 8.0 mm. From 1997 to 2017 the stripper with an oval-ring head was used in 1274 patients (male, n=421; female, n=853) for treating 1832 lower limbs. Average age was 46.4±12.3 years (range, 29 to 73). GSV and SSV stripping was performed in 1165 and 137 cases respectively in patients with the trunk diameter of more than 10 mm, severe vein tortuosity, for a vein located immediately under the skin, as well as for patients with the history of thrombophlebitis. The pain level in the 1st evening after the operation was 1.59, on the 7th day it decreased to 0.12 according to VAS-10. The motion activity level in the 1st evening after the operation was 7.24, on the 7th day it decreased to 9.96 according to VAS-10. All patients had primary wound healing. Hematomas along the location of the eliminated veins were of a moderate nature and resolved, on average, within 17 days. With the GSV diameter of 10-20 mm the skin scars were of 2.93 mm (95% CI: 3.09 mm - 4.47 mm), with the GSV diameter of more than 20 mm the skin scars were of 4.10 mm (95% CI: 4.01 mm - 5.07 mm). After 3 months 1102 patients (86,5%) were very satisfied and 172 (13,5%) were just satisfied with the performed operation. The use of the proposed stripper with an oval-ring head in patients with large-diameter subcutaneous trunks leads to the minimization of the skin incisions up to the punctures and, in general, makes the surgery significantly less traumatic, providing a quick recovery and minimization of the skin scars.

  16. 15 CFR 241.7 - Tolerances to be allowed.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... follows: Tolerance inches Diameter of head 1/4 Effective diameter of head 1/4 Distance between heads 1/4 Circumference of bulge, outside measurement 11/2 Length of stave 1/2 (1) If no dimension of a barrel of Class 1... the effective diameter of head and the distance between heads algebraically and multiply the result by...

  17. 15 CFR 241.7 - Tolerances to be allowed.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... follows: Tolerance inches Diameter of head 1/4 Effective diameter of head 1/4 Distance between heads 1/4 Circumference of bulge, outside measurement 11/2 Length of stave 1/2 (1) If no dimension of a barrel of Class 1... the effective diameter of head and the distance between heads algebraically and multiply the result by...

  18. 15 CFR 241.7 - Tolerances to be allowed.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... follows: Tolerance inches Diameter of head 1/4 Effective diameter of head 1/4 Distance between heads 1/4 Circumference of bulge, outside measurement 11/2 Length of stave 1/2 (1) If no dimension of a barrel of Class 1... the effective diameter of head and the distance between heads algebraically and multiply the result by...

  19. 15 CFR 241.7 - Tolerances to be allowed.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... follows: Tolerance inches Diameter of head 1/4 Effective diameter of head 1/4 Distance between heads 1/4 Circumference of bulge, outside measurement 11/2 Length of stave 1/2 (1) If no dimension of a barrel of Class 1... the effective diameter of head and the distance between heads algebraically and multiply the result by...

  20. Corrosion at the head-neck interface of current designs of modular femoral components: essential questions and answers relating to corrosion in modular head-neck junctions.

    PubMed

    Osman, K; Panagiotidou, A P; Khan, M; Blunn, G; Haddad, F S

    2016-05-01

    There is increasing global awareness of adverse reactions to metal debris and elevated serum metal ion concentrations following the use of second generation metal-on-metal total hip arthroplasties. The high incidence of these complications can be largely attributed to corrosion at the head-neck interface. Severe corrosion of the taper is identified most commonly in association with larger diameter femoral heads. However, there is emerging evidence of varying levels of corrosion observed in retrieved components with smaller diameter femoral heads. This same mechanism of galvanic and mechanically-assisted crevice corrosion has been observed in metal-on-polyethylene and ceramic components, suggesting an inherent biomechanical problem with current designs of the head-neck interface. We provide a review of the fundamental questions and answers clinicians and researchers must understand regarding corrosion of the taper, and its relevance to current orthopaedic practice. Cite this article: Bone Joint J 2016;98-B:579-84. ©2016 The British Editorial Society of Bone & Joint Surgery.

  1. Habitat suitability and nest survival of white-headed woodpeckers in unburned forests of Oregon

    Treesearch

    Jeff P. Hollenbeck; Vicki Saab; Richard W. Frenzel

    2011-01-01

    We evaluated habitat suitability and nest survival of breeding white-headed woodpeckers (Picoides albolarvatus) in unburned forests of central Oregon, USA. Daily nest-survival rate was positively related to maximum daily temperature during the nest interval and to density of large-diameter trees surrounding the nest tree. We developed a niche-based habitat suitability...

  2. Relationship between central and peripheral corneal astigmatism in elderly patients

    NASA Astrophysics Data System (ADS)

    Kawamorita, Takushi; Shimizu, Kimiya; Hoshikawa, Rie; Kamiya, Kazutaka; Shoji, Nobuyuki

    2018-03-01

    Abstract Purpose We investigated the relationship between central and peripheral corneal astigmatism in elderly patients. Methods Seventy-six eyes of 76 elderly subjects (mean age = 72.6 ± 3.0 years) were included in the study. Corneal shape was evaluated using the Pentacam HR (Oculus, Wetzlark, Germany), which is comprised of a rotating Scheimpflug camera and a short-wavelength slit light. The power distribution map was selected and corneal astigmatism was calculated using front K-Readings in zones centered on the pupil. Analyzed zones were 2.0-6.0 mm in diameter. Results Corneal astigmatism decreased as diameter increased, similar to what was observed in eyes with with-the-rule astigmatism and against-the-rule astigmatism (ANOVA, p < 0.01). This effect was more pronounced in eyes with a large central corneal astigmatism (Spearman's rank-correlation coefficient test, r = 0.51, p < 0.01). There was no change as to axis of corneal astigmatism (ANOVA, p = 0.98). Conclusion These results suggest that the relationship between central and peripheral corneal astigmatism should be taken into consideration to optimize vision when astigmatic correction is needed.

  3. Femoral head epiphysis growth and development among Chinese children aged 0-5 years.

    PubMed

    Luo, Jiayou; Tang, Jin; Zhou, Libo; Zeng, Rong; Mou, Jinsong; Zhang, Lingli

    2009-05-01

    The aim of this study was to examine the pattern of femoral head epiphysis growth and development among Chinese children. Between January and December, 2007, we randomly sampled 1,450 healthy Chinese children (0-5 years old) from Hunan Provincial Children's Hospital in Changsha, Hunan, China. The diameter of femoral head epiphysis was measured by pelvic X-ray photography and processed by medical image processing software. The growth of femoral head epiphysis in girls was 2-3 months earlier than that in boys. The diameter of femoral head epiphysis increased with advancing age in both girls and boys, but the diameter of femoral head epiphysis in 2, 3, 4, 6, and 10-month-old girls was significantly larger than that in boys. Cubic regression equations between the diameter of femoral head epiphysis and age were created for boys and girls that could be used to predict the diameter of femoral head epiphysis. In conclusion, there was gender difference in femoral head epiphysis growth and development among Chinese children, and our prediction models will provide the guidance for early diagnosis of diseases related to the growth and development of the femoral head epiphysis.

  4. What are the predictors and prevalence of pseudotumor and elevated metal ions after large-diameter metal-on-metal THA?

    PubMed

    Bayley, Nick; Khan, Habeeb; Grosso, Paul; Hupel, Thomas; Stevens, David; Snider, Matthew; Schemitsch, Emil; Kuzyk, Paul

    2015-02-01

    Soft tissue masses, or "pseudotumors," around metal-on-metal total hip arthroplasty (MoM THA) have been reported frequently; however, their prevalence remains unknown. Several risk factors, including elevated metal ion levels, have been associated with the presence of pseudotumor, although this remains controversial. The goals of this study were to (1) determine the prevalence of pseudotumors after large-diameter head MoM THA; (2) identify risk factors associated with pseudotumor formation and elevated metal ion levels; and (3) determine the early failure rate of large-diameter MoM THA. Between December 2005 and November 2012, 258 hips (215 patients) underwent large-diameter head primary MoM THA at our institution. Clinical followup was obtained in 235 hips (91%). Using an inclusion criteria of a minimum followup of 1 year, a subset of 191 hips (mean followup, 4 years; range, 1-7 years) was recruited for high-resolution ultrasound screening for the presence of pseudotumor. Whole blood cobalt and chromium ion levels, UCLA activity level, WOMAC score, patient demographics as well as surgical, implant, and radiographic data were collected. Bivariate correlations and multivariate log-linear regression models were used to compare the presence of pseudotumor and elevated metal ions with all other factors. Ultrasound detected a solid, cystic, or mixed mass in 20% hips (38 of 191). No correlation was found between the presence of pseudotumor and any risk factor that we examined. After controlling for confounding variables, elevated cobalt ions were correlated (p<0.001, R=0.50, R2=0.25) with smaller femoral head size, the presence of bilateral MoM THA, and female sex. Elevated chromium ions were correlated (p<0.001, R=0.59, R2=0.34) with smaller femoral head size, presence of bilateral MoM THA, and lower body mass index. The overall survival of MoM THA was 96% at a mean followup of 4.5 years (range, 2-8 years). With the numbers available, we found no associations between the presence of pseudotumor and the potential risk factors we analyzed, including elevated metal ion levels. Further work is needed to explain why larger femoral head sizes resulted in lower metal ion levels despite being associated with higher early failure rates in joint registry data. Level III, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.

  5. Trunnionosis: Does Head Size Affect Fretting and Corrosion in Total Hip Arthroplasty?

    PubMed

    Del Balso, Christopher; Teeter, Matthew G; Tan, Sok Chuen; Howard, James L; Lanting, Brent A

    2016-10-01

    Wear and tribocorrosion at the modular head-neck taper interface may be a cause of failure in metal-on-polyethylene total hip arthroplasty (THA). The present investigation endeavored to elucidate the effect of femoral head diameter on fretting and corrosion in retrieved head-neck tapers. A retrieval analysis of THA prostheses in vivo for a minimum of 1 year was performed. Twenty-three femoral heads of 32-mm diameter were matched with 28-mm heads based on time in vivo and head length (-3 mm to +8 mm). All included implants featured a single taper design from a single manufacturer. Fretting and corrosion damage scoring was performed for each implant under stereomicroscopic visualization. Head diameter was observed to affect fretting (P = .01), with 32-mm femoral heads exhibiting greater total fretting scores than 28-mm heads. Fretting damage was greatest (P = .01) in the central concentric zone of the femoral head bore tapers, regardless of head diameter, length, or stem offset. No significant effect on total corrosion scores was observed for any head or stem variable. Retrieved implant total corrosion scores were positively correlated (ρ = 0.51, P < .001) with implantation time. Increased femoral head diameter in THA may produce greater fretting damage owing to and increased head-neck moment arm. There is no associated increase in corrosion with 28-mm and 32-mm heads of this taper design. The longer a THA prosthesis is implanted, the greater the risk of damage due to corrosion. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. SLI Complex Curvature Friction Stir Weld Risk Reduction Program

    NASA Technical Reports Server (NTRS)

    Hartley, Paula J.; Schneider, Jules; Jones, Chip; Lawless, Kirby; Russell, Carolyn

    2003-01-01

    The Space Launch Initiative Program (SLI) in conjunction with the National Center for Advanced Manufacturing (NCAM) will demonstrate the ability to produce large-scale complex curvature hardware using the self-reacting friction stir welding process. This multi-phased risk reduction program includes friction stir welding process development and manufacture of a 22-ft diameter quarter dome using a conventional tooling approach; it culminates in a 27.5-ft diameter quarter dome demonstration performed on a 5-axis Universal Weld System. The design, fabrication, and installation of the Universal Weld System is made possible through a collaboration between the State of Louisiana, NASA, and the University of New Orleans. The Universal Weld System, manufactured by MTS Systems Corporation, will be installed at the Michoud Assembly Facility in New Orleans, Louisiana, and will be capable of manufacturing domes up to 30 ft in diameter. All welding will be accomplished using the Adaptable Adjustable Pin Tool (AdAPT) weld head and controller manufactured by MTS. Weld parameters will be developed for an aluminum alloy in gauges ranging from 0.320 to 0.400 in. thick. Weld quality will be verified through radiography, mechanical property testing at ambient and LN2 temperatures, and metallurgical analysis. The AdAPT weld head will then be mounted on a 22-ft diameter dome tool, which will be modified to include a welding track and drive system for moving the AdAPT weld head along the weld joint. This tool will then be used to manufacture a 22-ft diameter dome of an aluminum alloy, with 0.320-in. constant thickness joints, consisting of three individual gore panels. Finally, the 27.5-ft diameter quarter dome will be welded on the Universal Weld System. The quarter dome will consist of three individual gore panels with weld lands tapering from 0.320 to 0.360 in. in thickness. With the demonstration of these welds, the ability to manufacture large diameter domes using the friction stir weld process in conjunction with a universal weld system provides a low risk approach to the fabrication of aluminum tanks for future launch vehicle applications.

  7. Robotic-arm assisted total hip arthroplasty results in smaller acetabular cup size in relation to the femoral head size: a matched-pair controlled study.

    PubMed

    Suarez-Ahedo, Carlos; Gui, Chengcheng; Martin, Timothy J; Chandrasekaran, Sivashankar; Lodhia, Parth; Domb, Benjamin G

    2017-03-31

    To compare the acetabular component size relative to the patient's native femoral head size between conventional THA (CTHA) approach and robotic-arm assisted THA (RTHA) to infer which of these techniques preserved more acetabular bone. Patients were included if they had primary osteoarthritis (OA) and underwent total hip replacement between June 2008 and March 2014. Patients were excluded if they had missing or rotated postoperative anteroposterior radiographs. RTHA patients were matched to a control group of CTHA patients, in terms of preoperative native femoral head size, age, gender, body mass index (BMI) and approach. Acetabular cup size relative to femoral head size was used as a surrogate for amount of bone resected. We compared the groups according to 2 measures describing acetabular cup diameter (c) in relation to femoral head diameter (f): (i) c-f, the difference between cup diameter and femoral head diameter and (ii) (c-f)/f, the same difference as a fraction of femoral head diameter. 57 matched pairs were included in each group. There were no significant differences between groups for demographic measures, femoral head diameter, or acetabular cup diameter (p>0.05). However, measures (i) and (ii) did differ significantly between the groups, with lower values in the RTHA group (p<0.02). Using acetabular cup size relative to femoral head size as an approximate surrogate measure of acetabular bone resection may suggest greater preservation of bone stock using RTHA compared to CTHA. Further studies are needed to validate the relationship between acetabular cup size and bone loss in THA.

  8. Objective classification of different head and neck positions and their influence on the radiographic pharyngeal diameter in sport horses

    PubMed Central

    2014-01-01

    Background Various head and neck positions in sport horses are significant as they can interfere with upper airway flow mechanics during exercise. Until now, research has focused on subjectively described head and neck positions. The objective of this study was to develop an objective, reproducible method for quantifying head and neck positions accurately. Results Determining the angle between the ridge of the nose and the horizontal plane (ground angle) together with the angle between the ridge of nose and the line connecting the neck and the withers (withers angle) has provided values that allow precise identification of three preselected head and neck positions for performing sport horses. The pharyngeal diameter, determined on lateral radiographs of 35 horses, differed significantly between the established flexed position and the remaining two head and neck positions (extended and neutral). There was a significant correlation between the pharyngeal diameter and the ground angle (Spearman’s rank correlation coefficient −0.769, p < 0.01) as well as between the pharyngeal diameter and the withers angle (Spearman’s rank correlation coefficient 0.774, p < 0.01). Conclusion The combination of the ground angle and the withers angle is a suitable tool for evaluating and distinguishing frequently used head and neck positions in sport horses. The ground angle and the withers angle show significant correlation with the measured pharyngeal diameter in resting horses. Hence, these angles provide an appropriate method for assessing the degree of head and neck flexion. Further research is required to examine the influence of increasing head and neck flexion and the related pharyngeal diameter on upper airway function in exercising horses. PMID:24886564

  9. Reference charts of fetal biometric parameters in 31,476 Brazilian singleton pregnancies.

    PubMed

    Araujo Júnior, Edward; Martins Santana, Eduardo Félix; Martins, Wellington P; Júnior, Julio Elito; Ruano, Rodrigo; Pires, Claudio Rodrigues; Filho, Sebastião Marques Zanforlin

    2014-07-01

    The purpose of this study was to establish reference charts of fetal biometric parameters measured by 2-dimensional sonography in a large Brazilian population. A cross-sectional retrospective study was conducted including 31,476 low-risk singleton pregnancies between 18 and 38 weeks' gestation. The following fetal parameters were measured: biparietal diameter, head circumference, abdominal circumference, femur length, and estimated fetal weight. To assess the correlation between the fetal biometric parameters and gestational age, polynomial regression models were created, with adjustments made by the determination coefficient (R(2)). The means ± SDs of the biparietal diameter, head circumference, abdominal circumference, femur length, and estimated fetal weight measurements at 18 and 38 weeks were 4.2 ± 2.34 and 9.1 ± 4.0 cm, 15.3 ± 7.56 and 32.3 ± 11.75 cm, 13.3 ± 10.42 and 33.4 ± 20.06 cm, 2.8 ± 2.17 and 7.2 ± 3.58 cm, and 256.34 ± 34.03 and 3169.55 ± 416.93 g, respectively. Strong correlations were observed between all fetal biometric parameters and gestational age, best represented by second-degree equations, with R(2) values of 0.95, 0.96, 0.95, 0.95, and 0.95 for biparietal diameter, head circumference, abdominal circumference, femur length, and estimated fetal weight. Fetal biometric parameters were determined for a large Brazilian population, and they may serve as reference values in cases with a high risk of intrauterine growth disorders. © 2014 by the American Institute of Ultrasound in Medicine.

  10. Predictivity and fate of metal ion release from metal-on-metal total hip prostheses.

    PubMed

    Nicolli, Annamaria; Bisinella, Gianluca; Padovani, Giovanni; Vitella, Antonio; Chiara, Federica; Trevisan, Andrea

    2014-09-01

    Blood metal ion levels in 72 patients with large head metal-on-metal hip arthroplasty were studied to determine the correlation between the values measured in whole blood and urine. Urinary cobalt and chromium levels of 30μg and 21μg, respectively, adjusted to creatinine were found to correspond to the 7μg/l cut-off value that has been accepted in whole blood. Cobalt and chromium levels in whole blood and urine both significantly correlated with increased acetabular component inclination angle over 50 degrees and pain scores. There was no correlation with socket anteversion angle or femoral head diameter. The data support the use of urinary measurement of metal ions adjusted to creatinine to monitor patients with large head metal-on-metal total hip arthroplasty. Copyright © 2014 Elsevier Inc. All rights reserved.

  11. Evaluation of head and face injury potential of current airline seats during crash decelerations.

    DOT National Transportation Integrated Search

    1966-06-01

    A large percentage of deaths in commercial-airline crashes is produced as the body and lower limbs flail around the seat belt. According to a previous study, a 10-foot-diameter sphere of clear area would be necessary to prevent a person from striking...

  12. Pharyngeal diameter in various head and neck positions during exercise in sport horses

    PubMed Central

    2014-01-01

    Background In equine athletes, dynamic stenotic disorders of the upper airways are often the cause for abnormal respiratory noises and/or poor performance. There are hypotheses, that head and neck flexion may influence the morphology and function of the upper airway and thus could even induce or deteriorate disorders of the upper respiratory tract. Especially the pharynx, without osseous or cartilaginous support is prone to changes in pressure and airflow during exercise. The objective of this study was to develop a method for measuring the pharyngeal diameter in horses during exercise, in order to analyse whether a change of head-neck position may have an impact on the pharyngeal diameter. Results Under the assumption that the width of the epiglottis remains constant in healthy horses, the newly developed method for calculating the pharyngeal diameter in horses during exercise is unsusceptible against changes of the viewing-angle and distance between the endoscope and the structures, which are to be assessed. The quotient of the width of the epiglottis and the perpendicular from a fixed point on the dorsal pharynx to the epiglottis could be used to determine the pharyngeal diameter. The percentage change of this quotient (pharynx-epiglottis-ratio; PE-ratio) in the unrestrained head-neck position against the reference position was significantly larger than that of any other combination of the head-neck positions investigated. A relation between the percentage change in PE-ratio and the degree of head and neck flexion could not be confirmed. Conclusions It could be shown, that the pharyngeal diameter is reduced through the contact position implemented by the rider in comparison to the unrestrained head and neck position. An alteration of the pharyngeal diameter depending on the degree of head and neck flexion (represented by ground and withers angle) could not be confirmed. PMID:24886465

  13. Experimental study of geysers through a vent pipe connected to flowing sewers.

    PubMed

    Huang, Biao; Wu, Shiqiang; Zhu, David Z; Schulz, Harry E

    2017-04-01

    Geysers of air-water mixtures in urban drainage systems is receiving considerable attention due to public safety concerns. However, the geyser formation process and its relation with air release from pressurized pipes are still relatively little known. A large-scale physical model, that consisted of a main tunnel with a diameter of 270 mm and a length of 25 m connecting two reservoirs and a vertical vent pipe, was established to investigate geyser evolution and pressure transients. Experimental results including dynamic pressure data and high speed videos were analysed in order to characterize geysering flow through the vent pipe. Pressure transients were observed during geysering events. Their amplitudes were found to be about three times the driving pressure head and their periods were close to the classic surge tank predictions. The influence of flow rate and vent pipe size were examined: geyser heights and pressure peaks decreased for small flow rate and large diameter vent pipe. It is suggested that geyser heights are related with the pressure head and the density of the air-water mixture.

  14. Tribological assessment of a flexible carbon-fibre-reinforced poly(ether-ether-ketone) acetabular cup articulating against an alumina femoral head.

    PubMed

    Scholes, S C; Inman, I A; Unsworth, A; Jones, E

    2008-04-01

    New material combinations have been introduced as the bearing surfaces of hip prostheses in an attempt to prolong their life by overcoming the problems of failure due to wear-particle-induced osteolysis. This will hopefully reduce the need for revision surgery. The study detailed here used a hip simulator to assess the volumetric wear rates of large-diameter carbon-fibre-reinforced pitch-based poly(ether-ether-ketone) (CFR-PEEK) acetabular cups articulating against alumina femoral heads. The joints were tested for 25 x 10(6) cycles. Friction tests were also performed on these joints to determine the lubrication regime under which they operate. The average volumetric wear rate of the CFR-PEEK acetabular component of 54 mm diameter was 1.16 mm(3)/10(6) cycles, compared with 38.6 mm(3)/10(6) cycles for an ultra-high-molecular-weight polyethylene acetabular component of 28 mm diameter worn against a ceramic head. This extremely low wear rate was sustained over 25 x 10(6) cycles (the equivalent of up to approximately 25 years in vivo). The frictional studies showed that the joints worked under the mixed-boundary lubrication regime. The low wear produced by these joints showed that this novel joint couple offers low wear rates and therefore may be an alternative material choice for the reduction of osteolysis.

  15. Prediction of postnatal outcomes in fetuses with isolated congenital diaphragmatic hernias using different lung-to-head ratio measurements.

    PubMed

    Kehl, Sven; Siemer, Jörn; Brunnemer, Suna; Weiss, Christel; Eckert, Sven; Schaible, Thomas; Sütterlin, Marc

    2014-05-01

    The purpose of this study was to compare different methods for measuring the fetal lung area-to-head circumference ratio and to investigate their prediction of postpartum survival and the need for neonatal extracorporeal membrane oxygenation (ECMO) therapy in fetuses with isolated congenital diaphragmatic hernias. This prospective study included 118 fetuses of at least 20 weeks' gestation with isolated left-sided congenital diaphragmatic hernias. The lung-to-head ratio was measured with 3 different methods (longest diameter, anteroposterior diameter, and tracing). To eliminate the influence of gestational age, the observed-to-expected lung-to-head ratio was calculated. Receiver operating characteristic (ROC) curves were calculated for the statistical prediction of survival and need for ECMO therapy by the observed-to-expected lung-to-head ratio measured with the different methods. For survival and ECMO necessity 118 and 102 cases (16 neonates were not eligible for ECMO) were assessed, respectively. For prediction of postpartum survival and ECMO necessity, the areas under the ROC curves and 95% confidence intervals showed very similar results for the 3 methods for prediction of survival (tracing, 0.8445 [0.7553-0.9336]; longest diameter, 0.8248 [0.7360-0.9136]; and anteroposterior diameter, 0.8002 [0.7075-0.8928]) and for ECMO necessity (tracing, 0.7344 [0.6297-0.8391]; longest diameter, 0.7128 [0.6027-0.8228]; and anteroposterior diameter, 0.7212 [0.6142-0.8281]). Comparisons between the areas under the ROC curves showed that the tracing method was superior to the anteroposterior diameter method in predicting postpartum survival (P = .0300). Lung-to-head ratio and observed-to-expected lung-to-head ratio measurements were shown to accurately predict postnatal survival and the need for ECMO therapy in fetuses with left-sided congenital diaphragmatic hernias. Tracing the limits of the lungs seems to be the favorable method for calculating the fetal lung area.

  16. Two cases of exenteration of the brain from Brenneke shotgun slugs.

    PubMed

    Karger, B; Banaschak, S

    1997-01-01

    A case of extended suicide resulted in two fatalities due to craniocerebral gunshots from a 12-gauge shotgun firing Brenneke shotgun slugs. In each case, the gunshot shattered the skull and the brain and in one case, large parts of the brain including a complete hemisphere were ejected similar to a "Krönlein shot". The location of the trajectory close to the base of the skull, the muzzle gases and the ballistic characteristics of the missile contributed to this rare form of head injury. The high mass and the large diameter of the lead missile do not necessitate a high muzzle velocity to crush large amounts of tissue or to produce an explosive type of head injury. The wadding material and the metal screw attached to the Brenneke slug can be of forensic significance.

  17. 15 CFR 241.4 - Application of tolerance for “diameter of head.”

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the mean of the average diameters from inside to inside of staves at the inner edges of the heads. (2..., one taken from inside to inside of staves at the inner edge of the head, the other from inside to inside of staves at the inner edge of the croze ring, or from inside to inside of staves at a point where...

  18. Treatment of an old-growth stand and its effects on birds, ants, and large woody debris: A case study. Forest Service general technical report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bull, E.L.; Torgersen, T.R.; Blumton, A.K.

    1995-09-01

    An old-structure stand with large amounts of tree mortality was treated to accelerate regeneration and reduce fuel loads but still maintain its function as old growth for selected bird species. The smll-diameter (less than 15 inches in diameter at breast height (d.b.h.)), dead trees were removed as was some of the down wood less than 15 inches in diameter at the large end. All live trees of any size and all dead trees equal to or greater than 15 inches d.b.h. were retained. Vaux`s swifts (Chaetura vauxi) and pileated woodpeckers (Dryocopus pileatus) continued to use the stand after harvest formore » nesting and roosting. Brown-headed cowbirds (molothrus ater) were more than twice as common in the treated stand as in an adjacent unlogged, control stand. In a comparison before and after harvest in the treated stand, the number of logs increased, the number of logs with ants increased, but the percentage of logs with ants decreased.« less

  19. Study on compensation algorithm of head skew in hard disk drives

    NASA Astrophysics Data System (ADS)

    Xiao, Yong; Ge, Xiaoyu; Sun, Jingna; Wang, Xiaoyan

    2011-10-01

    In hard disk drives (HDDs), head skew among multiple heads is pre-calibrated during manufacturing process. In real applications with high capacity of storage, the head stack may be tilted due to environmental change, resulting in additional head skew errors from outer diameter (OD) to inner diameter (ID). In case these errors are below the preset threshold for power on recalibration, the current strategy may not be aware, and drive performance under severe environment will be degraded. In this paper, in-the-field compensation of small DC head skew variation across stroke is proposed, where a zone table has been equipped. Test results demonstrating its effectiveness to reduce observer error and to enhance drive performance via accurate prediction of DC head skew are provided.

  20. Cachexia induces head and neck changes in locally advanced oropharyngeal carcinoma during definitive cisplatin and image-guided volumetric-modulated arc radiation therapy.

    PubMed

    Mazzola, R; Ricchetti, F; Fiorentino, A; Di Paola, G; Fersino, S; Giaj Levra, N; Ruggieri, R; Alongi, F

    2016-06-01

    Cancer cachexia is a syndrome characterized by weight loss (WL) and sarcopenia. Aim of the study was to assess the impact of cachexia on head and neck changes during definitive cisplatin and image-guided volumetric-modulated arc radiation therapy in a series of locally advanced oropharyngeal cancer. Volume variations of sternocleidomastoid muscle (SCM) were considered as surrogate of muscle changes related to sarcopenia. Two head and neck diameters, encompassing the cranial limits of II and III nodal levels (defined as 'head diameter' and 'neck diameter', respectively), were measured. All parameters were defined retrospectively by means of on-board cone beam computed tomography images at 1-8th to 15-22th and at last fraction (fx) of radiotherapy (RT). Cachexia was defined as WL >5% during treatment. Analysis was conducted correlating the parameter changes with three WL ranges: <5, 5-9 and>10%. Thirty patients were evaluated. One hundred and fifty contoured SCMs and three hundred diameters were collected. Median WL was 6.5% (range, 0-16%). The most significant SCM shrinkage was recorded at 15th fx (mean 1.6 cc) related to WL 5-9% and WL >10% (P 0.001). For 'head diameter', the peak reduction was recorded at the 15th fx (mean 8 mm), statistically correlated to WL >10% (P 0.001). The peak reduction in 'neck diameter' was registered at the 22th fx (mean 6 mm), with a gradual reduction until the end of treatment for WL >5%. In a homogeneous cohort of patients, present study quantified the impact of cachexia on head and neck changes. Present data could provide adaptive RT implications for further investigations.

  1. Microvascular responses to body tilt in cutaneous maximus muscle of conscious rats

    NASA Technical Reports Server (NTRS)

    Puri, Rohit K.; Segal, Steven S.

    1994-01-01

    We investigated microvascular responses to head-up tilt (HUT) and head-down tilt (HDT) in striated muscle of conscious male rats. To observe the microcirculation in the cutaneous maximus muscle, a transparent polycarbonate chamber was implanted aseptically into a skin fold created between the shoulders. Rats were trained to sit quietly during HUT and HDT while positioned on a horizontal microscope that rotated in the sagittal plane. At 4-5 days after surgery, arteriole and venule diameters were recorded using videomicroscopy while the rat experienced 10 min each (in random order) of HUT or HDT at 20 deg or 40 deg separated by 2-h rest periods. HUT had no affect on microvessel diameter; 20 deg HDT had little affect. In response to 40 deg HDT, 'large' arterioles constricted by 18 +/- 2% and 'small' arterioles dilated by 21 +/- 3%; this difference suggested variation in mechanisms controlling arteriolar responses. Venules exhibited a larger fluctuation in diameter during 40 deg HDT compared with other body positions, suggesting that venomotor activity may be induced with sufficient fluid shift or change in central venous pressure. These observations illustrate a viable model for studying microvascular responses to gravitational stress in conscious rats.

  2. Design and analysis of a fast, two-mirror soft-x-ray microscope

    NASA Technical Reports Server (NTRS)

    Shealy, D. L.; Wang, C.; Jiang, W.; Jin, L.; Hoover, R. B.

    1992-01-01

    During the past several years, a number of investigators have addressed the design, analysis, fabrication, and testing of spherical Schwarzschild microscopes for soft-x-ray applications using multilayer coatings. Some of these systems have demonstrated diffraction limited resolution for small numerical apertures. Rigorously aplanatic, two-aspherical mirror Head microscopes can provide near diffraction limited resolution for very large numerical apertures. The relationships between the numerical aperture, mirror radii and diameters, magnifications, and total system length for Schwarzschild microscope configurations are summarized. Also, an analysis of the characteristics of the Head-Schwarzschild surfaces will be reported. The numerical surface data predicted by the Head equations were fit by a variety of functions and analyzed by conventional optical design codes. Efforts have been made to determine whether current optical substrate and multilayer coating technologies will permit construction of a very fast Head microscope which can provide resolution approaching that of the wavelength of the incident radiation.

  3. 9 CFR 313.15 - Mechanical; captive bolt.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... instruments on detonation deliver bolts of varying diameters and lengths through the skull and into the brain. Unconsciousness is produced immediately by physical brain destruction and a combination of changes in intracranial... a flattened circular head against the external surface of the animal's head over the brain. Diameter...

  4. 9 CFR 313.15 - Mechanical; captive bolt.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... instruments on detonation deliver bolts of varying diameters and lengths through the skull and into the brain. Unconsciousness is produced immediately by physical brain destruction and a combination of changes in intracranial... a flattened circular head against the external surface of the animal's head over the brain. Diameter...

  5. 9 CFR 313.15 - Mechanical; captive bolt.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... instruments on detonation deliver bolts of varying diameters and lengths through the skull and into the brain. Unconsciousness is produced immediately by physical brain destruction and a combination of changes in intracranial... a flattened circular head against the external surface of the animal's head over the brain. Diameter...

  6. [Determination of a Friction Coefficient for THA Bearing Couples].

    PubMed

    Vrbka, M; Nečas, D; Bartošík, J; Hartl, M; Křupka, I; Galandáková, A; Gallo, J

    2015-01-01

    The wear of articular surfaces is considered one of the most important factors limiting the life of total hip arthroplasty (THA). It is assumed that the particles released from the surface of a softer material induce a complex inflammatory response, which will eventually result in osteolysis and aseptic loosening. Implant wear is related to a friction coefficient which depends on combination of the materials used, roughness of the articulating surfaces, internal clearance, and dimensions of the prosthesis. The selected parameters of the bearing couples tested were studied using an experimental device based on the principle of a pendulum. Bovine serum was used as a lubricant and the load corresponded to a human body mass of 75 kg. The friction coefficient was derived from a curve of slowdown of pendulum oscillations. Roughness was measured with a device working on the principle of interferometry. Clearance was assessed by measuring diameters of the acetabular and femoral heads with a 3D optical scanner. The specimens tested included unused metal-on-highly cross-linked polyethylene, ceramic-on-highly cross-linked polyethylene and ceramic-on-ceramic bearing couples with the diameters of 28 mm and 36 mm. For each measured parameter, an arithmetic mean was calculated from 10 measurements. 1) The roughness of polyethylene surfaces was higher by about one order of magnitude than the roughness of metal and ceramic components. The Protasul metal head had the least rough surface (0.003 μm). 2) The ceramic-on-ceramic couples had the lowest clearance. Bearing couples with polyethylene acetabular liners had markedly higher clearances ranging from 150 μm to 545 μm. A clearance increased with large femoral heads (up to 4-fold in one of the couple tested). 3) The friction coefficient was related to the combination of materials; it was lowest in ceramic-on-ceramic surfaces (0.11 to 0.12) and then in ceramic-on-polyethylene implants (0.13 to 0.14). The friction coefficient is supposed to increase with a decreasing femoral head diameter. However, in the bearing couples with polyethylene liners manufactured by one company, paradoxically, the friction coefficient slightly increased with an increase in femoral head size from 28 mm to 36 mm. 4) The lowest friction moment (< 3.5 Nm) was found for ceramic-on-ceramic implants 28 mm in diameter; the highest values were recorded in metal-on-polyethylene bearing couples 36 mm in diameter (> 7 Nm). Although our study confirmed that the bearing couples produced by different manufacturers varied to some extent in the parameters studied, in our opinion, this variability was not significant because it was not within an order of magnitude in any of the tests. The study showed that both the friction coefficient and the friction moment are affected more by the combination of materials than by the diameter of a femoral head. The best results were achieved in ceramic-on-ceramic implants.

  7. Customized Fetal Growth Charts for Parents' Characteristics, Race, and Parity by Quantile Regression Analysis: A Cross-sectional Multicenter Italian Study.

    PubMed

    Ghi, Tullio; Cariello, Luisa; Rizzo, Ludovica; Ferrazzi, Enrico; Periti, Enrico; Prefumo, Federico; Stampalija, Tamara; Viora, Elsa; Verrotti, Carla; Rizzo, Giuseppe

    2016-01-01

    The purpose of this study was to construct fetal biometric charts between 16 and 40 weeks' gestation that were customized for parental characteristics, race, and parity, using quantile regression analysis. In a multicenter cross-sectional study, 8070 sonographic examinations from low-risk pregnancies between 16 and 40 weeks' gestation were analyzed. The fetal measurements obtained were biparietal diameter, head circumference, abdominal circumference, and femur diaphysis length. Quantile regression was used to examine the impact of parental height and weight, parity, and race across biometric percentiles for the fetal measurements considered. Paternal and maternal height were significant covariates for all of the measurements considered (P < .05). Maternal weight significantly influenced head circumference, abdominal circumference, and femur diaphysis length. Parity was significantly associated with biparietal diameter and head circumference. Central African race was associated with head circumference and femur diaphysis length, whereas North African race was only associated with femur diaphysis length. In this study we constructed customized biometric growth charts using quantile regression in a large cohort of low-risk pregnancies. These charts offer the advantage of defining individualized normal ranges of fetal biometric parameters at each specific percentile corrected for parental height and weight, parity, and race. This study supports the importance of including these variables in routine sonographic screening for fetal growth abnormalities.

  8. ANALYSIS OF LABOUR ACCIDENTS DUE TO ROCK FALL EVENTS IN CUTTING FACE OF TUNNEL AND STUDY OF THE COUNTERMEASURES FOR SAFETY

    NASA Astrophysics Data System (ADS)

    Kikkawa, Naotaka; Itoh, Kazuya; Hori, Tomohito; Tamate, Satoshi; Toyosawa, Yasuo

    In this paper, we analysed the labour accidents which had casualties due to rock fall events in the headings of tunnel and cleared the condition of the occurrence. It was clearly revealed that the accidents mostly happened when the workers mounted the explosive and the steel arch in the headings of the mountain tunnel. In addition, the dimension of the rocks fallen were averagely 0.6m diameter, it was not so much large. Therefore, the countermeasures based on both soft and hard faces would be useful and effective, such as the displacement measurement of a cutting face of tunnel, securing the sufficient lights to observe the cutting face, boring for drainage and shotcreting in a heading of tunnel.

  9. Crater density differences: Exploring regional resurfacing, secondary crater populations, and crater saturation equilibrium on the moon

    USGS Publications Warehouse

    Povilaitis, R Z; Robinson, M S; van der Bogert, C H; Hiesinger, Harald; Meyer, H M; Ostrach, Lillian

    2017-01-01

    The global population of lunar craters >20 km in diameter was analyzed by Head et al., (2010) to correlate crater distribution with resurfacing events and multiple impactor populations. The work presented here extends the global crater distribution analysis to smaller craters (5–20 km diameters, n = 22,746). Smaller craters form at a higher rate than larger craters and thus add granularity to age estimates of larger units and can reveal smaller and younger areas of resurfacing. An areal density difference map generated by comparing the new dataset with that of Head et al., (2010) shows local deficiencies of 5–20 km diameter craters, which we interpret to be caused by a combination of resurfacing by the Orientale basin, infilling of intercrater plains within the nearside highlands, and partial mare flooding of the Australe region. Chains of 5–30 km diameter secondaries northwest of Orientale and possible 8–22 km diameter basin secondaries within the farside highlands are also distinguishable. Analysis of the new database indicates that craters 57–160 km in diameter across much of the lunar highlands are at or exceed relative crater densities of R = 0.3 or 10% geometric saturation, but nonetheless appear to fit the lunar production function. Combined with the observation that small craters on old surfaces can reach saturation equilibrium at 1% geometric saturation (Xiao and Werner, 2015), this suggests that saturation equilibrium is a size-dependent process, where large craters persist because of their resistance to destruction, degradation, and resurfacing.

  10. Relation between flower head traits and florivory in Asteraceae: a phylogenetically controlled approach.

    PubMed

    Oguro, Michio; Sakai, Satoki

    2015-03-01

    • While much research has examined the relation between leaf traits and herbivory, very little is known about the interaction between floral traits, particularly biochemical traits, and florivory. We investigated patterns between floral traits and florivory across multiple species using phylogenetic comparative approaches to enhance our understanding of the evolution of plant-florivore interactions.• The relation between the intensity of florivory and five biochemical traits (concentrations of carbon, nitrogen, phosphorus, water, and total phenolics) and two morphological traits (diameter and number of flower heads) were investigated in wild individuals of 18 native species of Asteraceae. The phylogenetic signals in the morphological traits and intensity of florivory were also tested.• We found that species with higher nitrogen, water, and total phenolics and lower phosphorus concentrations in the flower heads and species with a large number and diameter of flower heads tended to be attacked by florivores. In addition, we found significant phylogenetic signals in florivory and morphological traits.• Our results clearly show that biochemical traits also play important roles in plant-florivore interactions, as previously shown in plant-leaf herbivore interactions. The positive relationship between florivory and total phenolics implies that phenolic compounds in flower heads may not act as a defense in the species. In addition, the observed pattern of signals in florivory might not be solely explained by the signals of the measured traits and other plant traits may also play significant roles in plant-florivore interaction in these species. © 2015 Botanical Society of America, Inc.

  11. Comparing discriminant analysis and neural network for the determination of sex using femur head measurements.

    PubMed

    Alunni, Véronique; Jardin, Philippe du; Nogueira, Luisa; Buchet, Luc; Quatrehomme, Gérald

    2015-08-01

    The measurement of the femoral head is usually considered an interesting variable for the sex determination of skeletal remains. To date, there are few published reference measurements of the femoral head in a modern European population for the purpose of sex determination. In this study, 116 femurs from 58 individuals of the South of France (Nice Bone Collection, Nice, France) were studied. Three measurements of the femoral head were taken: the vertical head diameter (VHD), the transversal head diameter (THD) and the head circumference (HC). The results show that: (i) there is no statistical difference between the right and left femurs for each of the three measurements (VHD, THD and HC). Therefore we arbitrarily chose to use the measures from the right femurs (N=58) to pursue our experiments; (ii) the measurements of the femoral head are similar to those of contemporary American populations; (iii) the dimensions of the femoral head place the measurements of the French population somewhere between Germany or Croatia, and Spain; (iv) there is no significant secular trend (in contrast with the femoral neck diameter); (v) the femoral head measurement as a single variable is useful for sex determination: a 96.5% rate of accuracy was obtained using THD and HC measurements with the artificial neural network; and a 94.8% rate of accuracy using VHD, both with the discriminant analysis and the neural network. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  12. Body mass and stature estimation based on the first metatarsal in humans.

    PubMed

    De Groote, Isabelle; Humphrey, Louise T

    2011-04-01

    Archaeological assemblages often lack the complete long bones needed to estimate stature and body mass. The most accurate estimates of body mass and stature are produced using femoral head diameter and femur length. Foot bones including the first metatarsal preserve relatively well in a range of archaeological contexts. In this article we present regression equations using the first metatarsal to estimate femoral head diameter, femoral length, and body mass in a diverse human sample. The skeletal sample comprised 87 individuals (Andamanese, Australasians, Africans, Native Americans, and British). Results show that all first metatarsal measurements correlate moderately to highly (r = 0.62-0.91) with femoral head diameter and length. The proximal articular dorsoplantar diameter is the best single measurement to predict both femoral dimensions. Percent standard errors of the estimate are below 5%. Equations using two metatarsal measurements show a small increase in accuracy. Direct estimations of body mass (calculated from measured femoral head diameter using previously published equations) have an error of just over 7%. No direct stature estimation equations were derived due to the varied linear body proportions represented in the sample. The equations were tested on a sample of 35 individuals from Christ Church Spitalfields. Percentage differences in estimated and measured femoral head diameter and length were less than 1%. This study demonstrates that it is feasible to use the first metatarsal in the estimation of body mass and stature. The equations presented here are particularly useful for assemblages where the long bones are either missing or fragmented, and enable estimation of these fundamental population parameters in poorly preserved assemblages. Copyright © 2011 Wiley-Liss, Inc.

  13. Catalogue of tooth brush head designs.

    PubMed

    Voelker, Marsha A; Bayne, Stephen C; Liu, Ying; Walker, Mary P

    2013-06-01

    Manual toothbrushes (MTBs) and power toothbrushes (PTBs) are effective oral physiotherapy aids for plaque removal. End-rounded bristles are safer and reduce damage to oral tissues. Nylon bristles are more effective in plaque removal because the bristle is stiffer than natural bristles. In the last 10 years the number of options for MTBs and PTBs has expanded significantly and there is very little information providing a reference frame for the design characteristics of the heads. The present in vitro study characterized a variety of MTB and PTB heads to provide a reference library for other research comparisons which might be made. Various commercial MTB and PTB heads were used to characterize the following: bristle size, shape, diameter, number of tufts, number of bristles per tuft and surface characteristics. Photographs were collected from the side, at 45 degrees and the top of each toothbrush (TB) head using a scanning electron microscope and digital camera. Images were analyzed (Soft Imaging System) for bristle features and designs. One-way ANOVA (p ≤ 0.05) was performed to detect differences among TB types within MTB and PTB groups and between pooled values for MTB and PTB groups. There were significant differences (p ≤ 0.05) in toothbrush bristle diameter and bristle shape. In contrast, there were no significant differences between PTB vs. MTB in regards to bristle diameter, bristle count and tuft count. The results suggest that although there are wide variations in toothbrush head designs, significant differences were found only in relation to bristle diameter and shape.

  14. Micro-scale pollution mechanism of dust diffusion in a blasting driving face based on CFD-DEM coupled model.

    PubMed

    Yu, Haiming; Cheng, Weimin; Xie, Yao; Peng, Huitian

    2018-05-23

    In order to investigate the diffuse pollution mechanisms of high-concentration dusts in the blasting driving face, the airflow-dust coupled model was constructed based on CFD-DEM coupled model; the diffusion rules of the dusts with different diameters at microscopic scale were analyzed in combination with the field measured results. The simulation results demonstrate that single-exhaust ventilation exhibited more favorable dust suppression performance than single-forced ventilation. Under single-exhaust ventilation condition, the motion trajectories of the dusts with the diameter smaller than 20 μm were close to the airflow streamline and these dusts were mainly distributed near the footway walls; by contrast, under single-forced ventilation condition, the motion trajectories of the dust particles with a diameter range of 20~40 μm were close to the airflow streamlines, and a large number of dusts with the diameter smaller than 20 μm accumulated in the regions 5 m and 17~25 m away from the head-on section. Moreover, under the single-exhaust ventilation, the relationship between dust diameter D and negative-pressured-induced dust emission ratio P can be expressed as P = - 25.03ln(D) + 110.39, and the dust emission ratio was up to 74.36% for 7-μm dusts, and the path-dependent settling behaviors of the dusts mainly occurred around the head-on section; under single-forced ventilation condition, the z value of the dusts with the diameter over 20 μm decreased and the dusts with a diameter smaller than 7 μm are particularly harmful to human health, but their settling ratios were below 22.36%. Graphical abstract The airflow-dust CFD-DEM coupling model was established. The numerical simulation results were verified. The migration laws of airflow field were obtained in a blasting driving face. The diffusion laws of dusts were obtained after blasting.

  15. Adjustable fetal phantom for pulse oximetry

    NASA Astrophysics Data System (ADS)

    Stubán, Norbert; Niwayama, Masatsugu

    2009-05-01

    As the measuring head of a fetal pulse oximeter must be attached to the head of the fetus inside the mother's uterus during labor, testing, and developing of fetal pulse oximeters in real environment have several difficulties. A fetal phantom could enable evaluation of pulse oximeters in a simulated environment without the restrictions and difficultness of medical experiments in the labor room. Based on anatomic data we developed an adjustable fetal head phantom with three different tissue layers and artificial arteries. The phantom consisted of two arteries with an inner diameter of 0.2 and 0.4 mm. An electronically controlled pump produced pulse waves in the arteries. With the phantom we investigated the sensitivity of a custom-designed wireless pulse oximeter at different pulsation intensity and artery diameters. The results showed that the oximeter was capable of identifying 4% and 2% changes in diameter between the diastolic and systolic point in arteries of over 0.2 and 0.4 mm inner diameter, respectively. As the structure of the phantom is based on reported anatomic values, the results predict that the investigated custom-designed wireless pulse oximeter has sufficient sensitivity to detect the pulse waves and to calculate the R rate on the fetal head.

  16. Sex estimation by femur in modern Thai population.

    PubMed

    Monum, T; Prasitwattanseree, S; Das, S; Siriphimolwat, P; Mahakkanukrauh, P

    2017-01-01

    Sex estimation is an important step of postmortem investigation and the femur is a useful bone for sex estimation by using metric analysis method. Even though there have been a reported sex estimation method by using femur in Thais, the temporal change related to time and anthropological data need to be renewed. Thus the aim of this study is to re-evaluate sex estimation by femur in Thais. 97 adult male and 103 female femora were random chosen from Forensic osteology research center and 6 measurements were applied tend to. To compare with previous Thai data, mid shaft diameter to increase but femoral head and epicondylar breadth to stabilize and when tested previous discriminant function by vertical head diameter and epicondalar breadth, the accuracy of prediction was lower than previous report. From the new data, epicondalar breadth is the best variable for distinguishing male and female at 88.7 percent of accuracy, following by transverse and vertical head diameter at 86.7 percent and femoral neck diameter at 81.7 percent of accuracy. Multivariate discriminant analysis indicated transverse head diameter and epicondylar breadth performed highest rate of accuracy at 89.7 percent. The percent of accuracy of femur was close to previous reported sex estimation by talus and calcaneus in Thai population. Thus, for especially in case of lower limb remain, which absence of pelvis.

  17. PowerWheel - A new look at waterwheels

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Weisman, R.N.; Broome, K.R.; Mayo, H.A.

    1995-12-31

    The PowerWheel is an advanced overshot water wheel, designed to generate electric power at drop structures on canals or on overflow spillways. Unlike the wheels of the 18th and 19th century which were designed to have maximum efficiency at a single flow rate, the current applications demand a wheel that can operate efficiently over a wide range of flows. The prototype PowerWheel will have a width to diameter ratio of 3 or more, in contrast to the wheels of the 19th century, which had large diameters and narrow widths. A model PowerWheel was built of plexiglass and delivered for testingmore » to the Imbt Hydraulics Laboratory at Lehigh University. The wheel has a diameter of 3.5 ft and is 16 in wide. The wheel contains 20 buckets and the bucket depth can be varied from a shallow depth of 4 in to a mid depth of 7 in to 10 in for the deep bucket. The blades have a rather simple geometry with a 4 in radius quarter circle at the outside of the wheel and then straight to the bottom of the bucket. The flume in which the wheel was tested has a width of 18 in. A hole was cut in the head box of the flume and a delivery chute was connected to the head box. The position of the chute can readily be moved up or down in relation to the wheel; for a fixed position of the chute on the head box, the slope of the chute can be changed because the chute was attached to the head box with a piano hinge. The laboratory flow system can deliver flow up to 6 cfs through a calibrated Venturi meter. The PowerWheel was subjected to flows ranging from 0.3 to 3.5 cfs.« less

  18. 15 CFR 241.5 - Standard dimensions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 133/8 115/8 Distance between heads 231/2 201/2 18 Circumference of bulge, outside measurement 581/2.../8 11 Distance between heads 23 20 171/2 Circumference of bulge, outside measurement 533/8 47 413/8... head 171/8 161/4 Effective diameter of head (see § 241.4) 163/4 157/8 Distance between heads 26 251/4...

  19. 15 CFR 241.5 - Standard dimensions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 133/8 115/8 Distance between heads 231/2 201/2 18 Circumference of bulge, outside measurement 581/2.../8 11 Distance between heads 23 20 171/2 Circumference of bulge, outside measurement 533/8 47 413/8... head 171/8 161/4 Effective diameter of head (see § 241.4) 163/4 157/8 Distance between heads 26 251/4...

  20. 15 CFR 241.5 - Standard dimensions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 133/8 115/8 Distance between heads 231/2 201/2 18 Circumference of bulge, outside measurement 581/2.../8 11 Distance between heads 23 20 171/2 Circumference of bulge, outside measurement 533/8 47 413/8... head 171/8 161/4 Effective diameter of head (see § 241.4) 163/4 157/8 Distance between heads 26 251/4...

  1. 15 CFR 241.5 - Standard dimensions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 133/8 115/8 Distance between heads 231/2 201/2 18 Circumference of bulge, outside measurement 581/2.../8 11 Distance between heads 23 20 171/2 Circumference of bulge, outside measurement 533/8 47 413/8... head 171/8 161/4 Effective diameter of head (see § 241.4) 163/4 157/8 Distance between heads 26 251/4...

  2. 15 CFR 241.5 - Standard dimensions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 133/8 115/8 Distance between heads 231/2 201/2 18 Circumference of bulge, outside measurement 581/2.../8 11 Distance between heads 23 20 171/2 Circumference of bulge, outside measurement 533/8 47 413/8... head 171/8 161/4 Effective diameter of head (see § 241.4) 163/4 157/8 Distance between heads 26 251/4...

  3. Growth trajectories of the human embryonic head and periconceptional maternal conditions.

    PubMed

    Koning, I V; Baken, L; Groenenberg, I A L; Husen, S C; Dudink, J; Willemsen, S P; Gijtenbeek, M; Koning, A H J; Reiss, I K M; Steegers, E A P; Steegers-Theunissen, R P M

    2016-05-01

    Can growth trajectories of the human embryonic head be created using 3D ultrasound (3D-US) and virtual reality (VR) technology, and be associated with second trimester fetal head size and periconceptional maternal conditions? Serial first trimester head circumference (HC) and head volume (HV) measurements were used to create reliable growth trajectories of the embryonic head, which were significantly associated with fetal head size and periconceptional maternal smoking, age and ITALIC! in vitro fertilization (IVF)/intra-cytoplasmic sperm injection (ICSI) treatment. Fetal growth is influenced by periconceptional maternal conditions. We selected 149 singleton pregnancies with a live born non-malformed fetus from the Rotterdam periconception cohort. Bi-parietal diameter and occipital frontal diameter to calculate HC, HV and crown-rump length (CRL) were measured weekly between 9 + 0 and 12 + 6 weeks gestational age (GA) using 3D-US and VR. Fetal HC was obtained from second trimester structural anomaly scans. Growth trajectories of the embryonic head were created with general additive models and linear mixed models were used to estimate associations with maternal periconceptional conditions as a function of GA and CRL, respectively. A total of 303 3D-US images of 149 pregnancies were eligible for embryonic head measurements (intra-class correlation coefficients >0.99). Associations were found between embryonic HC and fetal HC ( ITALIC! ρ = 0.617, ITALIC! P < 0.001) and between embryonic HV and fetal HC ( ITALIC! ρ = 0.660, ITALIC! P < 0.001) in ITALIC! Z-scores. Maternal periconceptional smoking was associated with decreased, and maternal age and IVF/ICSI treatment with increased growth trajectories of the embryonic head measured by HC and HV (All ITALIC! P < 0.05). The consequences of the small effect sizes for neurodevelopmental outcome need further investigation. As the study population consists largely of tertiary hospital patients, external validity should be studied in the general population. Assessment of growth trajectories of the embryonic head may be of benefit in future early antenatal care. This study was funded by the Department of Obstetrics and Gynaecology, Erasmus MC University Medical Centre and Sophia Foundation for Medical Research, Rotterdam, The Netherlands (SSWO grant number 644). No competing interests are declared. © The Author 2016. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  4. Birth weight and optic nerve head parameters.

    PubMed

    Samarawickrama, Chameen; Huynh, Son C; Liew, Gerald; Burlutsky, George; Mitchell, Paul

    2009-06-01

    To assess the relationship of birth weight, birth length, and head circumference as proxy markers of intrauterine growth, cup/disc ratio, and other optic disc parameters measured using optical coherence tomography (OCT). Population-based cross sectional analysis. The Sydney Childhood Eye Study examined 2353 primarily 12-year-old children from 21 randomly selected secondary schools during 2003 to 2005. Of 2353 children examined, 2134 (90.7%) had OCT scans (Zeiss Stratus OCT, Carl Zeiss Meditec, Dublin, CA) and are included in this study. The "fast" optic disc scan protocol was used. Birth weight, birth length, and head circumference were ascertained from health records. Height and weight were measured using standardized protocols, body mass index (BMI) was defined as weight (kilograms)/ height squared (meters), and sociodemographic information was collected in a questionnaire completed by parents. Low birth weight was defined as birth weight

  5. New formulas for calculating the lung-to-head ratio in healthy fetuses between 20 and 40 weeks' gestation.

    PubMed

    Kehl, Sven; Eckert, Sven; Berlit, Sebastian; Tuschy, Benjamin; Sütterlin, Marc; Siemer, Jörn

    2013-11-01

    The purpose of this study was to develop new formulas for the expected fetal lung area-to-head circumference ratio in normal singleton pregnancies between 20 and 40 weeks' gestation. The lung-to-head ratio and complete fetal biometric parameters of 126 fetuses between 20 and 40 weeks' gestation were prospectively measured. The lung-to-head ratio was measured by 3 different methods (longest diameter, anteroposterior diameter, and tracing). Formulas for predicting right and left lung-to-head ratios with regard to gestational age and biometric parameters were derived by stepwise regression analysis. New formulas for calculating right and left lung-to-head ratios by each measurement method were derived. The formulas included gestational age only and no biometric parameters. The new formulas for estimating the expected lung-to-head ratio by the 3 different methods in normal singleton pregnancies up to 40 weeks' gestation may help improve the prognostic power of observed-to-expected lung-to-head ratio assessment in fetuses with congenital diaphragmatic hernias.

  6. The Influence of Initial and Boundary Conditions on Gaseous Detonation Waves.

    DTIC Science & Technology

    1985-09-01

    in large diameter tubes. A theory dealing with the origin of spin was later advanced by Bone, Fraser and Wheeler (1935) based on Schlieren records...acoustic theories for the prediction of the spinning frequency of the transverse vibrations in and behind the reaction zone. The frequency of the single-head...Frazer simply corresponded to ’ other higher acoustic modes. An excellent description of the fine wechani- cal details of low-mode spinning detonations is

  7. Management of pancreatic pseudocysts—A retrospective analysis

    PubMed Central

    Nötzel, Bärbel; Phillip, Veit; Lahmer, Tobias; Schmid, Roland M.; Algül, Hana

    2017-01-01

    Background Pancreatic pseudocysts arise mostly in patients with alcohol induced chronic pancreatitis causing various symptoms and complications. However, data on the optimal management are rare. To address this problem, we analysed patients with pancreatic pseudocysts treated at our clinic retrospectively. Methods We searched our clinical database for the diagnosis pancreatitis from 2004 till 2014, selected patients with pseudocysts larger than 10 mm and entered all relevant information in a database for statistical analysis. Results In total, 129 patients with pancreatic pseudocysts were treated at our institution during the study period. Most patients suffered from alcohol induced chronic pancreatitis (43.4%; 56/129). Pseudocysts were more frequent in female than in male (2:1) and were mainly located in the pancreatic head (47.3%; 61/129). Local complications like obstructive jaundice were associated with the diameter of the cysts (AUC 0.697 in ROC-curve analysis). However, even cysts up to a diameter of 160 mm can regress spontaneously. Besides a lower re-intervention rate in surgically treated patients, endoscopic, percutaneous and surgical drainage are equally effective. Most treatment related complications occur in large pseudocysts located in the pancreatic head. Conclusion Conservative management of large pseudocysts is successful in many patients. Therefore, indication for treatment should be made carefully considering the presence and risk of local complications. Endoscopic and surgical drainage are equally effective. PMID:28877270

  8. TADPOLE GALAXIES IN THE HUBBLE ULTRA DEEP FIELD

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Elmegreen, Bruce G.; Elmegreen, Debra Meloy, E-mail: bge@watson.ibm.co, E-mail: elmegreen@vassar.ed

    2010-10-20

    Tadpole galaxies have a head-tail shape with a large clump of star formation at the head and a diffuse tail or streak of stars off to one side. We measured the head and tail masses, ages, surface brightnesses, and sizes for 66 tadpoles in the Hubble Ultra Deep Field (UDF) and looked at the distribution of neighbor densities and tadpole orientations with respect to neighbors. The heads have masses of 10{sup 7}-10{sup 8} M{sub sun} and photometric ages of {approx}0.1 Gyr for z {approx} 2. The tails have slightly larger masses than the heads and comparable or slightly older ages.more » The most obvious interpretation of tadpoles as young merger remnants is difficult to verify. They have no enhanced proximity to other resolved galaxies as a class, and the heads, typically <0.2 kpc in diameter, usually have no obvious double-core structure. Another possibility is ram pressure interaction between a gas-rich galaxy and a diffuse cosmological flow. Ram pressure can trigger star formation on one side of a galaxy disk, giving the tadpole shape when viewed edge-on. Ram pressure can also strip away gas from a galaxy and put it into a tail, which then forms new stars and gravitationally drags along old stars with it. Such an effect might have already been observed in the Virgo Cluster. Another possibility is that tadpoles are edge-on disks with large, off-center clumps. Analogous lop-sided star formation in UDF clump clusters is shown.« less

  9. Habitat relationships and nest site characteristics of cavity-nesting birds in cottonwood floodplains

    USGS Publications Warehouse

    Sedgwick, James A.; Knopf, Fritz L.

    1990-01-01

    We examined habitat relationships and nest site characteristics for 6 species of cavity-nesting birds--American kestrel (Falco sparverius), northern flicker (Colaptes auratus), red-headed woodpecker (Melanerpes erythrocephalus), black-capped chickadee (Parus atricapillus), house wren (Troglodytes aedon), and European starling (Sturnus vulgaris)--in a mature plains cottonwood (Populus sargentii) bottomland along the South Platte River in northeastern Colorado in 1985 and 1986. We examined characteristics of cavities, nest trees, and the habitat surrounding nest trees. Density of large trees (>69 cm dbh), total length of dead limbs ≥10 cm diameter (TDLL), and cavity density were the most important habitat variables; dead limb length (DLL), dbh, and species were the most important tree variables; and cavity height, cavity entrance diameter, and substrate condition at the cavity (live vs. dead) were the most important cavity variables in segregating cavity nesters along habitat, tree, and cavity dimensions, respectively. Random sites differed most from cavity-nesting bird sites on the basis of dbh, DLL, limb tree density (trees with ≥1 m dead limbs ≥10 cm diameter), and cavity density. Habitats of red-headed woodpeckers and American kestrels were the most unique, differing most from random sites. Based on current trends in cottonwood demography, densities of cavity-nesting birds will probably decline gradually along the South Platte River, paralleling a decline in DLL, limb tree density, snag density, and the concurrent lack of cottonwood regeneration.

  10. A systematic examination of the bone destruction pattern of the two-shot technique

    PubMed Central

    Stoetzer, Marcus; Stoetzer, Carsten; Rana, Majeed; Zeller, Alexander; Hanke, Alexander; Gellrich, Nils-Claudius; von See, Constantin

    2014-01-01

    Introduction: The two-shot technique is an effective stopping power method. The precise mechanisms of action on the bone and soft-tissue structures of the skull; however, remain largely unclear. The aim of this study is to compare the terminal ballistics of the two-shot and single-shot techniques. Materials and Methods: 40 fresh pigs’ heads were randomly divided into 4 groups (n = 10). Either a single shot or two shots were fired at each head with a full metal jacket or a semi-jacketed bullet. Using thin-layer computed tomography and photography, the diameter of the destruction pattern and the fractures along the bullet path were then imaged and assessed. Results: A single shot fired with a full metal jacket bullet causes minor lateral destruction along the bullet path. With two shots fired with a full metal jacket bullet, however, the maximum diameter of the bullet path is significantly greater (P < 0.05) than it is with a single shot fired with a full metal jacket bullet. In contrast, the maximum diameter with a semi-jacketed bullet is similar with the single-shot and two-shot techniques. Conclusion: With the two-shot technique, a full metal jacket bullet causes a destruction pattern that is comparable to that of a single shot fired with a semi-jacketed bullet. PMID:24812454

  11. Fetal head detection and measurement in ultrasound images by a direct inverse randomized Hough transform

    NASA Astrophysics Data System (ADS)

    Lu, Wei; Tan, Jinglu; Floyd, Randall C.

    2005-04-01

    Object detection in ultrasound fetal images is a challenging task for the relatively low resolution and low signal-to-noise ratio. A direct inverse randomized Hough transform (DIRHT) is developed for filtering and detecting incomplete curves in images with strong noise. The DIRHT combines the advantages of both the inverse and the randomized Hough transforms. In the reverse image, curves are highlighted while a large number of unrelated pixels are removed, demonstrating a "curve-pass filtering" effect. Curves are detected by iteratively applying the DIRHT to the filtered image. The DIRHT was applied to head detection and measurement of the biparietal diameter (BPD) and head circumference (HC). No user input or geometric properties of the head were required for the detection. The detection and measurement took 2 seconds for each image on a PC. The inter-run variations and the differences between the automatic measurements and sonographers" manual measurements were small compared with published inter-observer variations. The results demonstrated that the automatic measurements were consistent and accurate. This method provides a valuable tool for fetal examinations.

  12. Habitat suitability and nest survival of white-headed woodpeckers in unburned forests of Oregon

    USGS Publications Warehouse

    Hollenbeck, Jeff P.; Saab, Victoria A.; Frenzel, Richard W.

    2011-01-01

    We evaluated habitat suitability and nest survival of breeding white-headed woodpeckers (Picoides albolarvatus) in unburned forests of central Oregon, USA. Daily nest-survival rate was positively related to maximum daily temperature during the nest interval and to density of large-diameter trees surrounding the nest tree. We developed a niche-based habitat suitability model (partitioned Mahalanobis distance) for nesting white-headed woodpeckers using remotely sensed data. Along with low elevation, high density of large trees, and low slope, our habitat suitability model suggested that interspersion–juxtaposition of low- and high-canopy cover ponderosa pine (Pinus ponderosa) patches was important for nest-site suitability. Cross-validation suggested the model performed adequately for management planning at a scale >1 ha. Evaluation of mapped habitat suitability index (HSI) suggested that the maximum predictive gain (HSI = 0.36), where the number of nest locations are maximized in the smallest proportion of the modeled landscape, provided an objective initial threshold for identification of suitable habitat. However, managers can choose the threshold HSI most appropriate for their purposes (e.g., locating regions of low–moderate suitability that have potential for habitat restoration). Consequently, our habitat suitability model may be useful for managing dry coniferous forests for white-headed woodpeckers in central Oregon; however, model validation is necessary before our model could be applied to other locations.

  13. Cerebral blood velocity and other cardiovascular responses to 2 days of head-down tilt

    NASA Technical Reports Server (NTRS)

    Frey, Mary A. B.; Mader, Thomas H.; Bagian, James P.; Charles, John B.; Meehan, Richard T.

    1993-01-01

    Spaceflight induces a cephalad redistribution of fluid volume and blood flow within the human body, and space motion sickness, which is a problem during the first few days of space flight, could be related to these changes in fluid status and in blood flow of the cerebrum and vestibular system. To evaluate possible changes in cerebral blood flow during simulated weightlessness, we measured blood velocity in the middle cerebral artery (MCA) along with retinal vascular diameters, intraocular pressure, impedance cardiography, and sphygmomanometry on nine men (26.2 +/- 6.6 yr) morning and evening for 2 days during continuous 10 deg head-down tilt (HDT). When subjects went from seated to head-down bed rest, their heart rate and retinal diameters decreased, and intraocular pressures increased. After 48 h of HDT, blood flow velocity in the MCA was decreased and thoracic impedance was increased, indicating less fluid in the thorax. Percent changes in blood flow velocities in the MCA after 48 h of HDT were inversely correlated with percent changes in retinal vascular diameters. Blood flow velocities in the MCA were inversely correlated (intersubject) with arterial pressures and retinal vascular diameters. Heart rate, stroke volume, cardiac output, systolic arterial pressure, and at times pulse pressure and blood flow velocities in the MCA were greater in the evening. Total peripheral resistance was higher in the morning. Although cerebral blood velocity is reduced after subjects are head down for 2 days, the inverse relationship with retinal vessel diameters, which have control analogous to that of cerebral vessels, indicates cerebral blood flow is not reduced.

  14. Targeted intracellular voltage recordings from dendritic spines using quantum-dot-coated nanopipettes

    NASA Astrophysics Data System (ADS)

    Jayant, Krishna; Hirtz, Jan J.; Plante, Ilan Jen-La; Tsai, David M.; de Boer, Wieteke D. A. M.; Semonche, Alexa; Peterka, Darcy S.; Owen, Jonathan S.; Sahin, Ozgur; Shepard, Kenneth L.; Yuste, Rafael

    2017-05-01

    Dendritic spines are the primary site of excitatory synaptic input onto neurons, and are biochemically isolated from the parent dendritic shaft by their thin neck. However, due to the lack of direct electrical recordings from spines, the influence that the neck resistance has on synaptic transmission, and the extent to which spines compartmentalize voltage, specifically excitatory postsynaptic potentials, albeit critical, remains controversial. Here, we use quantum-dot-coated nanopipette electrodes (tip diameters ∼15-30 nm) to establish the first intracellular recordings from targeted spine heads under two-photon visualization. Using simultaneous somato-spine electrical recordings, we find that back propagating action potentials fully invade spines, that excitatory postsynaptic potentials are large in the spine head (mean 26 mV) but are strongly attenuated at the soma (0.5-1 mV) and that the estimated neck resistance (mean 420 MΩ) is large enough to generate significant voltage compartmentalization. Nanopipettes can thus be used to electrically probe biological nanostructures.

  15. Targeted intracellular voltage recordings from dendritic spines using quantum-dot-coated nanopipettes

    PubMed Central

    Jayant, Krishna; Hirtz, Jan J.; Plante, Ilan Jen-La; Tsai, David M.; De Boer, Wieteke D. A. M.; Semonche, Alexa; Peterka, Darcy S.; Owen, Jonathan S.; Sahin, Ozgur; Shepard, Kenneth L.; Yuste, Rafael

    2017-01-01

    Dendritic spines are the primary site of excitatory synaptic input onto neurons, and are biochemically isolated from the parent dendritic shaft by their thin neck. However, due to the lack of direct electrical recordings from spines, the influence that the neck resistance has on synaptic transmission, and the extent to which spines compartmentalize voltage, specifically excitatory postsynaptic potentials, albeit critical, remains controversial. Here, we use quantum-dot-coated nanopipette electrodes (tip diameters ~15–30 nm) to establish the first intracellular recordings from targeted spine heads under two-photon visualization. Using simultaneous somato-spine electrical recordings, we find that back propagating action potentials fully invade spines, that excitatory postsynaptic potentials are large in the spine head (mean 26 mV) but are strongly attenuated at the soma (0.5–1 mV) and that the estimated neck resistance (mean 420 MΩ) is large enough to generate significant voltage compartmentalization. Nanopipettes can thus be used to electrically probe biological nanostructures. PMID:27941898

  16. Targeted intracellular voltage recordings from dendritic spines using quantum-dot-coated nanopipettes.

    PubMed

    Jayant, Krishna; Hirtz, Jan J; Plante, Ilan Jen-La; Tsai, David M; De Boer, Wieteke D A M; Semonche, Alexa; Peterka, Darcy S; Owen, Jonathan S; Sahin, Ozgur; Shepard, Kenneth L; Yuste, Rafael

    2017-05-01

    Dendritic spines are the primary site of excitatory synaptic input onto neurons, and are biochemically isolated from the parent dendritic shaft by their thin neck. However, due to the lack of direct electrical recordings from spines, the influence that the neck resistance has on synaptic transmission, and the extent to which spines compartmentalize voltage, specifically excitatory postsynaptic potentials, albeit critical, remains controversial. Here, we use quantum-dot-coated nanopipette electrodes (tip diameters ∼15-30 nm) to establish the first intracellular recordings from targeted spine heads under two-photon visualization. Using simultaneous somato-spine electrical recordings, we find that back propagating action potentials fully invade spines, that excitatory postsynaptic potentials are large in the spine head (mean 26 mV) but are strongly attenuated at the soma (0.5-1 mV) and that the estimated neck resistance (mean 420 MΩ) is large enough to generate significant voltage compartmentalization. Nanopipettes can thus be used to electrically probe biological nanostructures.

  17. Correlation between retinal nerve fibre layer thickness and optic nerve head size: an optical coherence tomography study.

    PubMed

    Savini, G; Zanini, M; Carelli, V; Sadun, A A; Ross-Cisneros, F N; Barboni, P

    2005-04-01

    To investigate the correlation between retinal nerve fibre layer (RNFL) thickness and optic nerve head (ONH) size in normal white subjects by means of optical coherence tomography (OCT). 54 eyes of 54 healthy subjects aged between 15 and 54 underwent peripapillary RNFL thickness measurement by a series of three circular scans with a 3.4 mm diameter (Stratus OCT, RNFL Thickness 3.4 acquisition protocol). ONH analysis was performed by means of six radial scans centred on the optic disc (Stratus OCT, Fast Optic Disc acquisition protocol). The mean RNFL values were correlated with the data obtained by ONH analysis. The superior, nasal, and inferior quadrant RNFL thickness showed a significant correlation with the optic disc area (R = 0.3822, p = 0.0043), (R = 0.3024, p = 0.026), (R = 0.4048, p = 0.0024) and the horizontal disc diameter (R = 0.2971, p = 0.0291), (R = 0.2752, p = 0.044), (R = 0.3970, p = 0.003). The superior and inferior quadrant RNFL thickness was also positively correlated with the vertical disc diameter (R = 0.3774, p = 0.0049), (R = 0.2793, p = 0.0408). A significant correlation was observed between the 360 degrees average RNFL thickness and the optic disc area and the vertical and horizontal disc diameters of the ONH (R = 0.4985, p = 0.0001), (R = 0.4454, p = 0.0007), (R = 0.4301, p = 0.0012). RNFL thickness measurements obtained by Stratus OCT increased significantly with an increase in optic disc size. It is not clear if eyes with large ONHs show a thicker RNFL as a result of an increased amount of nerve fibres or to the shorter distance between the circular scan and the optic disc edge.

  18. Development of the monitoring technique on the damage of piles using the biggest shaking table "E-defense"

    NASA Astrophysics Data System (ADS)

    Hayashi, Kazuhiro; Hachimori, Wataru; Kaneda, Shogo; Tamura, Shuji; Saito, Taiki

    2017-10-01

    In case of earthquake damage to buildings, the damage to a superstructure is visible, but the damage to a foundation structure, e.g. the underground pile, is difficult to detect. In this study, the authors aim to develop a monitoring technique for pile damage due to earthquakes. The world's biggest shaking table, E-Defense, was used to reproduce damage to RC pile models embedded in the soil inside a large scale shear box (8m in diameter and 6.5m in height). The diameter of the RC pile model was 154mm. It consisted of mortar (27.2N/mm2 in compressive strength), 6 main reinforcements (6.35mm in diameter) and shear reinforcement hard steel wire (2mm in diameter at intervals of 20mm). The natural period of the superstructure above the pile models is around 0.12sec. The soil consisted of 2 layers. The lower layer is Albany sand of 80% relative density while the upper layer is only 2m from the surface ground and is Kaketsu sand of 60% relative density. Primary four excitations were scaled from JMA Kobe waves in notification at different amplitudes. The maximum acceleration of each wave is 31gal, 67gal, 304gal, and 458gal, respectively. In the test result, reinforcing steels at the pile head of the RC model yielded when the maximum acceleration was 304gal. After that, mortar of the pile head peeled off and a bending shear failure occurred when the maximum acceleration was 458gal. The peak frequency of rotational spectrum on the foundation did not change in elastic range in the piles. However, the peak frequency fell after the plastic hinge occurred.

  19. MATERNAL HEIGHT AND PRE-PREGNANCY WEIGHT STATUS ARE ASSOCIATED WITH FETAL GROWTH PATTERNS AND NEWBORN SIZE.

    PubMed

    Pölzlberger, Eva; Hartmann, Beda; Hafner, Erich; Stümpflein, Ingrid; Kirchengast, Sylvia

    2017-05-01

    The impact of maternal height, pre-pregnancy weight status and gestational weight gain on fetal growth patterns and newborn size was analysed using a dataset of 4261 singleton term births taking place at the Viennese Danube Hospital between 2005 and 2013. Fetal growth patterns were reconstructed from three ultrasound examinations carried out at the 11th/12th, 20th/21th and 32th/33th weeks of gestation. Crown-rump length, biparietal diameter, fronto-occipital diameter, head circumference, abdominal transverse diameter, abdominal anterior-posterior diameter, abdominal circumference and femur length were determined. Birth weight, birth length and head circumference were measured immediately after birth. The vast majority of newborns were of normal weight, i.e. between 2500 and 4000 g. Maternal height showed a just-significant but weak positive association (r=0.03: p=0.039) with crown-rump length at the first trimester and with the majority of fetal parameters at the second trimester (r>0.06; p0.09; p0.08; p0.17; p0.13; p0.13; p<0.001), were significantly positively associated with newborn size. Some of these associations were quite weak and the statistical significance was mainly due to the large sample size. The association patterns between maternal height and pre-pregnancy weight status with fetal growth patterns (p<0.001), as well as newborn size (p<0.001), were independent of maternal age, nicotine consumption and fetal sex. In general, taller and heavier women gave birth to larger infants. This association between maternal size and fetal growth patterns was detectable from the first trimester onwards.

  20. [Which hip articulation bearing for which patient? : Tribology of the future].

    PubMed

    Morlock, M M; Bishop, N; Kaddick, C

    2011-12-01

    Replacement of the hip joint has become an exceptionally successful procedure since the inauguration of the low friction principle by Charnley. Aseptic osteolysis and joint dislocation have been addressed by the development of wear-optimized materials and the introduction of larger heads. As an increase in head diameter against polyethylene causes wear increase, larger hard-on-hard bearings were introduced, which exhibit reduced wear and reduced dislocation risk with increasing head diameter. These findings were derived from standard simulator testing, not sufficiently considering the risk of fluid film breakdown under adverse conditions, which can cause a dramatic increase in wear and friction proportional to the head diameter. Such adverse conditions can occur clinically in patients due to several factors and have caused the presently observed unexpected problems with these new designs. Standardized preclinical testing has to be viewed as a minimum requirement but certainly not as a guarantee for the clinical success of new materials and designs even if the testing is adapted to the current patient requirements, which is presently not the case. The future of tribology lies in the prevention of adverse conditions in patients, the improvement and optimized use of proven existing materials and not in the use of new materials.

  1. Could larger diameter of 4th generation ceramic bearing decrease the rate of dislocation after THA?

    PubMed

    Lee, Young-Kyun; Ha, Yong-Chan; Jo, Woo-Lam; Kim, Tae-Young; Jung, Woon-Hwa; Koo, Kyung-Hoi

    2016-05-01

    Fourth generation (Delta) ceramic bearing was developed to reduce dislocation after total hip arthroplasty (THA) by increasing the head diameter. We tested a hypothesis that 32/36 mm Delta ceramic bearing decreases the dislocation rate. We also evaluated ceramic-related complications and early outcome of this thin liner-on-large head ceramic bearing. We performed a prospective study on patients who underwent THA with use of 32/36 mm Delta ceramic bearing. The dislocation rate was compared with the historical dislocation rate of third generation 28 mm ceramic bearing. We also evaluated ceramic fracture, squeak, short-term results and survival. Follow-up period was minimum 2 years. Between April 2010 and February 2012, we enrolled 250 consecutive patients (278 hips). All patients received cementless prostheses. Four patients (4 hips) who received metal shells ≤ 46 mm and 28 mm heads were excluded. Three patients died and 2 patients were lost within 2 years. The remaining 241 patients (269 hips) were followed for 24-46 months. There were 142 men (161 hips) and 99 women (108 hips) with a mean age of 53.7 years (range, 17-75 years) at the index operation. Dislocation occurred in three hips (1.1%). An old age was a risk factor for dislocation. Ceramic fracture and squeaking did not occur in any patient. Mean Harris hip score was 90.3 points at the latest follow-up. All acetabular and femoral components had bone-ingrowth stability. No hip had detectable wear or osteolysis. The survival was 99.3% in the best case scenario and 97.8% in the worst at 48 months. Total hip arthroplasty with use of 32/36 mm Delta ceramic bearing showed lower incidence of hip dislocation compared with 28 mm third generation ceramic bearing. A caution should be paid to prevent a fall in senile patients even though a large head is used. The short-term results of THA with this type of ceramic articulation are encouraging and we did not find any ceramic-related complications. Copyright © 2016 The Japanese Orthopaedic Association. Published by Elsevier B.V. All rights reserved.

  2. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Seibert, JA; Boone, JM

    Purpose: Phantom development in medical physics plays an important role in radiation dose assessment and image quality evaluation, and this is especially true in the pediatric patient population. The purpose of this investigation was to establish the relationship between patient age and patient size, focusing on the abdomen-pelvis and head effective diameters, for patients ranging in age from newborn to 18 years. Methods: A dose reporting tool for computed tomography systems was installed at our institution to achieve compliance with state law commencing on July 1, 2012. The software records a number of patient-specific data, and also reports CT dosemore » metrics (CTDIvol and DLP) into the patients interpretive report. The database generated by the software was mined to determine patient effective diameter as a function of age for pediatric patients aged 0–18 years. CT protocols including abdomen-pelvis and routine head were evaluated, and specific to this study the patients age, gender and equivalent diameter were recorded. Results: Six age ranges were evaluated: A(0–3), B(4–6), C(7–9), D(10–12),E(13–15),F(16–18). For the torso in these groups based upon 694 patients, median effective diameters were 147, 167, 184, 214, 231, 246 mm, respectively. For the head (N=1833), median diameters were 143, 157, 162, 168, 174, and 174, respectively. Conclusion: A solid understanding of the approximate dimensions of pediatric patients as a function of age is useful in the development of age-based imaging protocols and dose assessments. CT dose-reporting tools generate a great deal of data with respect to body dimensions automatically. In this study, median equivalent diameters for the abdomen-pelvis and head of pediatric patients were evaluated. These data may prove useful in the development of both mathematical and physical phantoms for dosimetry and image quality assessment.« less

  3. Effect of head contact on the rim of the cup on the offset loading and torque in hip joint replacement.

    PubMed

    Liu, Feng; Williams, Sophie; Jin, Zhongmin; Fisher, John

    2013-11-01

    Head contact on the rim of the cup causes stress concentration and consequently increased wear. The head contact on the rim of the cup may in addition cause an offset load and torque on the cup. The head-rim contact resulting from microseparation or subluxation has been investigated. An analytical model has been developed to calculate the offset loading and resultant torque on the cup as a function of the translational displacement of the head under simplified loading condition of the hip joint at heel strike during a walking cycle. The magnitude of the torque on the cup was found to increase with the increasing translational displacement, larger diameter heads, eccentric cups, and the coefficient of friction of the contact. The effects of cup inclination, cup rim radius, and cup coverage angle on the magnitude of the torque were found to be relatively small with a maximum variation in the torque magnitude being lower than 20%. This study has shown an increased torque due to the head loading on the rim of the cup, and this may contribute to the incidence of cup loosening. Particularly, metal-on-metal hip joints with larger head diameters may produce the highest offset loading torque.

  4. Magnetocardiogram measured by fundamental mode orthogonal fluxgate array

    NASA Astrophysics Data System (ADS)

    Karo, Hikaru; Sasada, Ichiro

    2015-05-01

    Magnetocardiography (MCG) of healthy volunteers has been measured by using a fundamental mode orthogonal fluxgate magnetometer array of 32 channels in a magnetic shielded room (MSR). Sensor heads, which are employed, consist of a 45 mm long U-shaped amorphous wire core and a 1000-turn solenoid pick-up coil of 30 mm in length and 3 mm in outer diameter. The excitation current of 100 kHz with large dc bias current is fed directly into wire cores, which are connected in series, whereas the signal detection circuit is provided to each of the sensor heads. A special technique to avoid mutual interaction between sensor heads is implemented, where all the sensor heads are excited synchronously by using a single ac source. A 2-D array having 32 sensors with 4 cm grid spacing was used to measure MCG signals inside an MSR. Measured data from each channel were first filtered (0.16-100 Hz pass band), then averaged for 2 min synchronously with electrocardiogram's peaks taken from both hands. Noise remaining after the average is about 1.8 pTrms for the band-width of 0.16-100 Hz. The QRS complex and the T-wave are clearly detected.

  5. Silicon Ingot Casting: Heat Exchanger Method. Multi-wire Slicing: Fixed Abrasine Slicing Technique, Phase 3

    NASA Technical Reports Server (NTRS)

    Schmid, F.; Khattak, C. P.

    1979-01-01

    Ingot casting was scaled up to 16 cm by 16 cm square cross section size and ingots weighing up to 8.1 kg were cast. The high degree of crystallinity was maintained in the large ingot. For large sizes, the nonuniformity of heat treatment causes chipping of the surface of the ingot. Progress was made in the development of a uniform graded structure in the silica crucibles. The high speed slicer blade-head weight was reduced to 37 pounds, allowing surface speeds of up to 500 feet per minute. Slicing of 10 cm diameter workpieces at these speeds increased the through-put of the machine to 0.145 mm/min.

  6. Air-Operated Sump Pump

    NASA Technical Reports Server (NTRS)

    Nolt, Gary D.

    1988-01-01

    Pump removes liquid seepage from small, restricted area and against large pressure head. Developed for moving small amounts of water and oil from sump pit 85 ft (25.91 m) deep. Fits in space only 6 1/2 in. (16.5 cm) in diameter and 18 in. (45.7 cm) long. In discharge part of pumping cycle, air forces liquid out of pump chamber through pipe. During filling part of pumping cycle, water enters pump chamber from sump pit. Float in chamber next to pump chamber controls pressurization through timer and solenoid valve.

  7. Meeting today's requirements for large thermal vacuum test facilities

    NASA Technical Reports Server (NTRS)

    Corinth, R. L.; Rouse, J. A.

    1986-01-01

    The Lockheed Thermal Vacuum Facility at Sunnyvale, California, completed in late 1986, one of the largest multi-program facilities constructed to date is described. The horizontal 12.2 m diameter by 24.4 m long chamber has removable heads at each end and houses a thermal shroud providing a test volume 10.4 m diameter by 24.4 m long. The chamber and thermal shroud are configured to permit the insertion of a 6.1 m wide by 24.4 m long vibration isolated optical bench. The pumpimg system incorporates an internal cryopumping array, turbomolecular pumps and cryopumps to handle multi-program needs and ranges of gas loads. The high vacuum system is capable of achieving clean, dry and empty pressures below 1.3 times 10 to the minus 6 power Pa (10 to the minus 8 power torr.)

  8. The Risk Factors for Hydrocephalus and Subdural Hygroma after Decompressive Craniectomy in Head Injured Patients.

    PubMed

    Ki, Hee Jong; Lee, Hyung-Jin; Lee, Hong-Jae; Yi, Jin-Seok; Yang, Ji-Ho; Lee, Il-Woo

    2015-09-01

    The present study aims to investigate 1) the risk factors for hydrocephalus and subdural hygroma (SDG) occurring after decompressive craniectomy (DC), and 2) the association between the type of SDG and hydrocephalus. We retrospectively reviewed the clinical and radiological features of 92 patients who underwent DC procedures after severe head injuries. The risk factors for developing post-traumatic hydrocephalus (PTH) and SDG were analyzed. Types of SDGs were classified according to location and their relationship with hydrocephalus was investigated. Ultimately, 26.09% (24/92) of these patients developed PTH. In the univariate analyses, hydrocephalus was statically associated with large bone flap diameter, large craniectomy area, bilateral craniectomy, intraventricular hemorrhage, contralateral or interhemisheric SDGs, and delayed cranioplasty. However, in the multivariate analysis, only large craniectomy area (adjusted OR=4.66; p=0.0239) and contralateral SDG (adjusted OR=6.62; p=0.0105) were significant independent risk factors for developing hydrocephalus after DC. The incidence of overall SDGs after DC was 55.43% (51/92). Subgroup analysis results were separated by SDG types. Statistically significant associations between hydrocephalus were found in multivariate analysis in the contralateral (adjusted OR=5.58; p=0.0074) and interhemispheric (adjusted OR=17.63; p=0.0113) types. For patients who are subjected to DC following severe head trauma, hydrocephalus is associated with a large craniectomy area and contralateral SDG. For SDGs after DC that occur on the interhemispherical or controlateral side of the craniectomy, careful follow-up monitoring for the potential progression into hydrocephalus is needed.

  9. Incision of Licus Vallis, Mars, From Multiple Lake Overflow Floods

    NASA Astrophysics Data System (ADS)

    Goudge, Timothy A.; Fassett, Caleb I.

    2018-02-01

    Licus Vallis is a large valley (>350 km long, >2 km wide, and >150 m deep) that heads at the outlet breach of an 30 km diameter impact crater. We present observations of the geomorphology and topography of this paleolake outlet valley and associated tributary valleys to constrain the history of incision of the Licus Vallis system. Licus Vallis has an abrupt increase in gradient by a factor of approximately 4 along its longitudinal profile, and a knickpoint that drops 200 m over a reach of 2 km approximately 12 km downstream from the valley head. We also describe a set of paired terraces within Licus Vallis, which are continuous for tens of kilometers and define an interior valley >2 km in width. We interpret the geomorphology of Licus Vallis as recording at least two discrete, major episodes of valley incision, both driven by lake overflow floods. The main portion of Licus Vallis formed by overflow flooding from a large ( 103-104 km2) lake contained in an intercrater basin. Subsequently, overflow flooding from a lake within the 30 km diameter impact crater reactivated Licus Vallis, forming a major knickpoint at the valley head and establishing the upstream section of the valley at a lower slope. Farther down the valley, this flood event incised an interior valley bounded by paired terraces. Regional tributary valleys that feed Licus Vallis also have prominent knickpoints, which have retreated farthest for downstream valleys. We conclude that these knickpoints record successive waves of incision that swept up Licus Vallis during lake overflow flooding, with erosion in the main trunk of the valley (from overflow floods) significantly outpacing erosion in the tributary valleys (from regional surface runoff). These observations of Licus Vallis illustrate how lake overflow floods may have provided an important control on the pace of landscape evolution on Mars.

  10. Femoral head asymmetry and coxa magna: anatomic study.

    PubMed

    Young, Ernest Y; Gebhart, Jeremy J; Bajwa, Navkirat; Cooperman, Daniel R; Ahn, Nicholas U

    2014-06-01

    Coxa magna, the asymmetrical circumferential enlargement of the femoral head, is an important sequela of pediatric disorders such as Legg-Calvé-Perthes disease. Definitions vary because of lack of controls and a scarcity of research on the distribution of the femoral head asymmetry. This study aims at defining the normal distribution of asymmetry between the left and the right femoral head and neck in the population and how demographics affect these properties. The study also looked at the distribution of side dominance (left or right). This study measured 230 paired femurs from individuals (20 to 40 y old) distributed for sex and ethnicity. The height and weight of the individuals were also recorded. The femoral head diameter and minimal femoral neck diameter in the anteroposterior view were measured on each paired femurs. The absolute and percent differences were determined to define asymmetry. Most of the population fell within 3% of asymmetry for the femoral head and 4% for the femoral neck. The maximum head percent asymmetry was 7.4%. Absolute difference in millimeters to percent asymmetry showed a ratio of 2:1 for the femoral head and 3:1 for the femoral neck. African Americans showed greater femoral head symmetry and a bias toward left-sided femoral head and neck enlargement when compared with their white counterparts. There was a high degree of symmetry between the left and right femoral heads and necks, which supports definitions found in the literature that define coxa magna above 10%. This study defines asymmetry in the femoral head in the normal population, which will help to define a quantitative definition of coxa magna.

  11. Cutting head for ultrasonic lithotripsy

    NASA Technical Reports Server (NTRS)

    Anguluo, E. D.; Goodfriend, R. (Inventor)

    1985-01-01

    A cutting head for attachment to the end of the wire probe of an ultrasonic kidney stone disintegration instrument is described. The cutting head has a plurality of circumferentially arranged teeth formed at one end thereof to provide a cup shaped receptacle for kidney stones encountered during the disintegration procedure. An integral reduced diameter collar diminishes stress points in the wire and reduce breakage thereof.

  12. Cutting Head for Ultrasonic Lithotripsy

    NASA Technical Reports Server (NTRS)

    Angulo, Earl D. (Inventor); Goodfriend, Roger (Inventor)

    1989-01-01

    A cutting head for attachment to the end of the wire probe of an ultrasonic kidney stone disintegration instrument. The cutting head has a plurality of circumferentially arranged teeth formed at one end thereof to provide a cup-shaped receptacle for kidney stones encountered during the disintegration procedure. An integral reduced diameter collar diminishes stress points in the wire and reduces breakage thereof.

  13. [Ultrasonic measurements of fetal thalamus, caudate nucleus and lenticular nucleus in prenatal diagnosis].

    PubMed

    Yang, Ruiqi; Wang, Fei; Zhang, Jialing; Zhu, Chonglei; Fan, Limei

    2015-05-19

    To establish the reference values of thalamus, caudate nucleus and lenticular nucleus diameters through fetal thalamic transverse section. A total of 265 fetuses at our hospital were randomly selected from November 2012 to August 2014. And the transverse and length diameters of thalamus, caudate nucleus and lenticular nucleus were measured. SPSS 19.0 statistical software was used to calculate the regression curve of fetal diameter changes and gestational weeks of pregnancy. P < 0.05 was considered as having statistical significance. The linear regression equation of fetal thalamic length diameter and gestational week was: Y = 0.051X+0.201, R = 0.876, linear regression equation of thalamic transverse diameter and fetal gestational week was: Y = 0.031X+0.229, R = 0.817, linear regression equation of fetal head of caudate nucleus length diameter and gestational age was: Y = 0.033X+0.101, R = 0.722, linear regression equation of fetal head of caudate nucleus transverse diameter and gestational week was: R = 0.025 - 0.046, R = 0.711, linear regression equation of fetal lentiform nucleus length diameter and gestational week was: Y = 0.046+0.229, R = 0.765, linear regression equation of fetal lentiform nucleus diameter and gestational week was: Y = 0.025 - 0.05, R = 0.772. Ultrasonic measurement of diameter of fetal thalamus caudate nucleus, and lenticular nucleus through thalamic transverse section is simple and convenient. And measurements increase with fetal gestational weeks and there is linear regression relationship between them.

  14. Highly crosslinked polyethylene: a safe alternative to conventional polyethylene for dual mobility cup mobile component. A biomechanical validation.

    PubMed

    Malatray, Matthieu; Roux, Jean-Paul; Gunst, Stanislas; Pibarot, Vincent; Wegrzyn, Julien

    2017-03-01

    Dual mobility cup (DMC) consists of a cobalt-chromium (CoCr) alloy cup articulated with a polyethylene (PE) mobile component capturing the femoral head in force using a snap-fit technique. This biomechanical study was the first to evaluate and compare the generation of cracks in the retentive area of DMC mobile components made of highly crosslinked PE (XLPE) or conventional ultra-high molecular weight PE (UHMWPE). Eighty mobile components designed for a 52-mm diameter Symbol® DMC (Dedienne Santé, Mauguio, France) and a 28-mm diameter femoral head were analyzed. Four groups of 20 mobile components were constituted according to the PE material: raw UHMWPE, sterilized UHMWPE, annealed XLPE and remelted XLPE. Ten mobile components in each group were impacted with a 28-mm diameter CoCr femoral head using a snap-fit technique. The occurrence, location and area of the cracks in the retentive area were investigated using micro-CT (Skyscan 1176®, Bruker, Aarsellar, Belgium) with a 35 μm nominal isotropic voxel size by two observers blinded to the PE material and impaction or not of the mobile components. Compared to conventional UHMWPE, the femoral head snap-fit did not generate more or wider cracks in the retentive area of annealed or remelted XLPE mobile components. This biomechanical study suggests that XLPE in DMC could be a safe alternative to conventional UHMWPE regarding the generation of cracks in the retentive area related to the femoral head snap-fit.

  15. Femoral head necrosis: A finite element analysis of common and novel surgical techniques.

    PubMed

    Cilla, Myriam; Checa, Sara; Preininger, Bernd; Winkler, Tobias; Perka, Carsten; Duda, Georg N; Pumberger, Matthias

    2017-10-01

    Femoral head necrosis is a common cause of secondary osteoarthritis. At the early stages, treatment strategies are normally based on core decompression techniques, where the number, location and diameter of the drilling holes varies depending on the selected approach. The purpose of this study was to investigate the risk of femoral head, neck and subtrochanteric fracture following six different core decompression techniques. Five common and a newly proposed techniques were analyzed in respect to their biomechanical consequences using finite element analysis. The geometry of a femur was reconstructed from computed-tomography images. Thereafter, the drilling configurations were simulated. The strains in the intact and drilled femurs were determined under physiological, patient-specific, muscle and joint contact forces. The following results were observed: i) - an increase in collapse and fracture risk of the femur head by disease progression ii) - for a single hole approach at the subtrochanteric region, the fracture risk increases with the diameter iii) - the highest fracture risks occur for an 8mm single hole drilling at the subtrochanteric region and approaches with multiple drilling at various entry points iv) - the proposed novel approach resulted in the most physiological strains (closer to the experienced by the healthy bone). Our results suggest that all common core decompression methods have a significant impact on the biomechanical competence of the proximal femur and impact its mechanical potential. Fracture risk increases with drilling diameter and multiple drilling with smaller diameter. We recommend the anterior approach due to its reduced soft tissue trauma and its biomechanical performance. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Demonstration of a broad band spectral head-mounted display with freeform mirrors.

    PubMed

    Pan, Jui-Wen; Che-Wen, Chiang; Huang, Kuan-Da; Wu, Chung-Yu

    2014-06-02

    It has been demonstrated that electrical stimulation of the retina can produce visual perception for blind patients suffering from macular degeneration and retinitis pigmentosa. In order to let the retinal chip generate enough electrical stimulation, the near infrared ray source is added to enhance the stimulation current. However, it is a challenge to design a head-mounted display (HMD) that covers both visible and infrared rays. Since the HMD system covers such a broad spectral band, large color aberrations will be induced. In order to eliminate these large aberrations, a mirror system is adopted that will create a no color aberration system. We also use two freeform mirrors (FFMs) to reduce residual aberrations such as spherical aberrations and coma. The FFMs serve as the near-eye viewing optics that magnifies the image which is displayed through a microdisplay. Based on a 0.61 in. microdisplay, the HMD system demonstrates a diagonal field of view (FOV) of 30 degree and an f/# of 3.75, with an exit pupil diameter of 8 mm and eye clearance of 15mm.

  17. A spreading drop model for plumes on Venus

    NASA Astrophysics Data System (ADS)

    Koch, D. M.

    1994-01-01

    Many of the large-scale, plume-related features on Venus can be modeled by a buoyant viscous drop, or plume head, as it rises and spreads laterally below a free fluid surface. The drop has arbitrary density and viscosity contrast and begins as a sphere below the surface of a fluid half space. The boundary integral method is used to solve for the motion of the plume head and for the topography, geoid, and stress at the fluid surface. As the plume approaches the surface, stresses in the fluid above it cause it to spread and become thin below the surface. During the spreading, the surface swell above evolves through various stages whose morphologies resemble several different plume-related features observed on Venus. When the plume head first approaches the surface, a high broad topographic dome develops, with a large geoid, and radial extensional deformation patterns. At later stages, the topography subsides and becomes plateau-like, the geoid to topography ratio (GTR) decreases, and the dominant stress pattern consists of a band of concentric extension surrounded by a band of concentric compression. We find that a low-viscosity model plume head (viscosity that is 0.1 times the mantle viscosity) produces maximum topography that is 20% lower, and swell features which evolve faster, than for an isoviscous plume. We compare model results with both the large-scale highland swells, and smaller-scale features such as coronae and novae. The dome-shaped highlands with large GTRs such as Beta, Atla, and Western Eistla Regiones may be the result of early stage plume motion, while the flatter highlands such as Ovda and Thetis Regiones which have lower GTRs may be later stage features. Comparison of model results with GTR data indicates that the highlands result from plume heads with initial diameters of about 1000 km. On a smaller scale, an evolutionary sequence may begin with novae (domes having radial extensional deformation), followed by features with radial and concentric deformation (such as arachnoids), and end with coronae (with mostly concentric deformation). The model predicts that the highlands evolve on a timescale of order 10 Ma, and the smaller-scale features evolve in a 100 Ma timescale.

  18. A pilot study demonstrating the feasibility of supermicrosurgical end-to-side anastomosis onto large recipient vessels in head and neck reconstruction.

    PubMed

    Iida, Takuya; Yoshimatsu, Hidehiko; Yamamoto, Takumi; Koshima, Isao

    2016-12-01

    In head and neck reconstruction using free flaps, microvascular anastomosis is commonly performed in an end-to-end fashion to relatively sizable arteries including the superficial temporal, facial, and superior thyroid arteries. With the recent developments of less invasive perforator flaps such as the superficial circumflex iliac artery perforator flap, anastomosis of smaller vessels of less than 0.8 mm diameter has become necessary; however, appropriate recipient arteries for end-to-end anastomosis are often absent. We have introduced supermicrosurgical end-to-side anastomosis to such arteries in 12 cases of head and neck reconstruction. Double-needle, short-thread microsutures were used to facilitate this procedure, and indocyanine green intraoperative angiography was used to confirm patency. All patients, except one with partial necrosis, survived. We believe that our method is a safe and reliable option for cases in which there is a discrepancy between the flap pedicle and recipient arteries. Copyright © 2016 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

  19. A morphological and morphometric study of proximal and distal ends of dry radii with its clinical implications.

    PubMed

    Gupta, Chandni; Kalthur, Sneha Guruprasad; Malsawmzuali, J C; D'souza, Antony Sylvan

    2015-01-01

    Knowledge of the size and shape of radial head is essential for construction of radial head prosthesis. Further, the measurements of bicipital tuberosity and its angular relationship to radial head are significant in surgical techniques, like in the reconstruction of biceps tendon. Even the morphometry of the distal radius is significant in numerous clinical orthopedic situations such as reduction of distal radius fractures and in the design of distal radius prosthesis. So, the aim of the study was to determine the morphometric parameters of proximal and distal radius in dry adult Indian radius. Fifty intact adult Indian radius (right = 23, left = 27) were chosen, and the various parameters of proximal and distal ends of radius were studied. Student's t-test was done to correlate all these parameters on the right and left sides. The mean length of radius, height of head at medial and lateral ends, head anteroposterior and transverse diameter, head thickness at ventral, dorsal, and lateral ends were 23.5, 0.90, 0.75, 1.91, 1.85, 0.42, 0.32, and 0.30 cm, respectively. The mean depth of articular facet, length of neck, proximal and distal neck diameter, width and length of bicipital tuberosity, and radial circumference at bicipital tuberosity were 0.19, 1.19, 1.36, 1.31, 1.23, 1.97, and 4.54 cm, respectively. The mean length of styloid process, oblique and transverse width of lower end, anteroposterior diameter of lower end, and angle of radial inclination were 0.98cm, 2. 81cm, 2.59cm, 1.86cm, and 25.05°, respectively. This study will be useful for orthopedic surgeons in making prosthesis for the proximal and distal ends of radius.

  20. 49 CFR 572.122 - Head assembly and test procedure.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... head CG may not be less than 245 G or more than 300 G. The resultant acceleration vs. time history... and the head must be oriented to an incline of 62 ±1 deg. between the “D” plane as shown in Figure N1 and the plane of the impact surface. The 1.57 mm (0.062 in) diameter holes located on either side of...

  1. Anthropometric and craniofacial patterns in mentally retarded males with emphasis on the fragile X syndrome.

    PubMed

    Butler, M G; Pratesi, R; Watson, M S; Breg, W R; Singh, D N

    1993-09-01

    Anthropometric and craniofacial profile patterns indicating the percent difference from the overall mean were developed on 34 physical parameters with 31 white, mentally retarded males (23 adults and 8 children) with the fra(X) syndrome matched for age with 31 white, mentally retarded males without a known cause of their retardation. The fra(X) syndrome males consistently showed larger dimensions for all anthropometric variables, with significant differences for height, sitting height, arm span, hand length, middle finger length, hand breadth, foot length, foot breadth, and testicular volume. A craniofacial pattern did emerge between the two groups of mentally retarded males, but with overlap of several variables. Significant differences were noted for head circumference, head breadth, lower face height, bizygomatic diameter, inner canthal distance, ear length and ear width, with the fra(X) syndrome males having larger head dimensions (head circumference, head breadth, head length, face height and lower face height), but smaller measurements for minimal frontal diameter, bizygomatic diameter, bigonial diameter, and inner canthal distance. Several significant correlations were found with the variables for both mentally retarded males with and without the fra(X) syndrome. In a combined anthropometric and craniofacial profile of 19 variables comparing 26 white fra(X) syndrome males (13 with high expression (> 30%) and 13 with low expression (< 30%), but matched for age), a relatively flat profile was observed with no significant differences for any of the variables. Generally, fra(X) syndrome males with increased fragile X chromosome expression have larger amplifications of the CGG trinucleotide repeat of the FMR-1 gene. No physical differences were detectable in our study between fra(X) males with high expression and apparently larger amplifications of the CGG trinucleotide repeats compared with those patients with low expression. Our research illustrates the use of anthropometry in identifying differences between mentally retarded males with or without the fra(X) syndrome and offers a comprehensive approach for screening males for the fra(X) syndrome and selecting those individuals for cytogenetic and/or molecular genetic testing.

  2. Anthropometric and craniofacial patterns in mentally retarded males with emphasis on the fragile X syndrome

    PubMed Central

    Butler, Merlin G.; Pratesi, Riccardo; Watson, Michael S.; Breg, W. Roy; Singh, Dharmdeo N.

    2017-01-01

    Anthropometric and craniofacial profile patterns indicating the percent difference from the overall mean were developed on 34 physical parameters with 31 white, mentally retarded males (23 adults and 8 children) with the fra(X) syndrome matched for age with 31 white, mentally retarded males without a known cause of their retardation. The fra(X) syndrome males consistently showed larger dimensions for all anthropometric variables, with significant differences for height, sitting height, arm span, hand length, middle finger length, hand breadth, foot length, foot breadth, and testicular volume. A craniofacial pattern did emerge between the two groups of mentally retarded males, but with overlap of several variables. Significant differences were noted for head circumference, head breadth, lower face height, bizygomatic diameter, inner canthal distance, ear length and ear width, with the fra(X) syndrome males having larger head dimensions (head circumference, head breadth, head length, face height and lower face height), but smaller measurements for minimal frontal diameter, bizygomatic diameter, bigonial diameter, and inner canthal distance. Several significant correlations were found with the variables for both mentally retarded males with and without the fra(X) syndrome. In a combined anthropometric and craniofacial profile of 19 variables comparing 26 white fra(X) syndrome males (13 with high expression (>30%) and 13 with low expression (< 30%), but matched for age), a relatively flat profile was observed with no significant differences for any of the variables. Generally, fra(X) syndrome males with increased fragile X chromosome expression have larger amplifications of the CGG trinucleotide repeat of the FMR-1 gene. No physical differences were detectable in our study between fra(X) males with high expression and apparently larger amplifications of the CGG trinucleotide repeats compared with those patients with low expression. Our research illustrates the use of anthropometry in identifying differences between mentally retarded males with or without the fra(X) syndrome and offers a comprehensive approach for screening males for the fra(X) syndrome and selecting those individuals for cytogenetic and/or molecular genetic testing. PMID:8275570

  3. Automatic Fastening Large Structures: a New Approach

    NASA Technical Reports Server (NTRS)

    Lumley, D. F.

    1985-01-01

    The external tank (ET) intertank structure for the space shuttle, a 27.5 ft diameter 22.5 ft long externally stiffened mechanically fastened skin-stringer-frame structure, was a labor intensitive manual structure built on a modified Saturn tooling position. A new approach was developed based on half-section subassemblies. The heart of this manufacturing approach will be 33 ft high vertical automatic riveting system with a 28 ft rotary positioner coming on-line in mid 1985. The Automatic Riveting System incorporates many of the latest automatic riveting technologies. Key features include: vertical columns with two sets of independently operating CNC drill-riveting heads; capability of drill, insert and upset any one piece fastener up to 3/8 inch diameter including slugs without displacing the workpiece offset bucking ram with programmable rotation and deep retraction; vision system for automatic parts program re-synchronization and part edge margin control; and an automatic rivet selection/handling system.

  4. To Be or Not To Be T4: Evidence of a Complex Evolutionary Pathway of Head Structure and Assembly in Giant Salmonella Virus SPN3US

    PubMed Central

    Ali, Bazla; Desmond, Maxim I.; Mallory, Sara A.; Benítez, Andrea D.; Buckley, Larry J.; Weintraub, Susan T.; Osier, Michael V.; Black, Lindsay W.; Thomas, Julie A.

    2017-01-01

    Giant Salmonella phage SPN3US has a 240-kb dsDNA genome and a large complex virion composed of many proteins for which the functions of most are undefined. We recently determined that SPN3US shares a core set of genes with related giant phages and sequenced and characterized 18 amber mutants to facilitate its use as a genetic model system. Notably, SPN3US and related giant phages contain a bolus of ejection proteins within their heads, including a multi-subunit virion RNA polymerase (vRNAP), that enter the host cell with the DNA during infection. In this study, we characterized the SPN3US virion using mass spectrometry to gain insight into its head composition and the features that its head shares with those of related giant phages and with T4 phage. SPN3US has only homologs to the T4 proteins critical for prohead shell formation, the portal and major capsid proteins, as well as to the major enzymes essential for head maturation, the prohead protease and large terminase subunit. Eight of ~50 SPN3US head proteins were found to undergo proteolytic processing at a cleavage motif by the prohead protease gp245. Gp245 undergoes auto-cleavage of its C-terminus, suggesting this is a conserved activation and/or maturation feature of related phage proteases. Analyses of essential head gene mutants showed that the five subunits of the vRNAP must be assembled for any subunit to be incorporated into the prohead, although the assembled vRNAP must then undergo subsequent major conformational rearrangements in the DNA packed capsid to allow ejection through the ~30 Å diameter tail tube for transcription from the injected DNA. In addition, ejection protein candidate gp243 was found to play a critical role in head assembly. Our analyses of the vRNAP and gp243 mutants highlighted an unexpected dichotomy in giant phage head maturation: while all analyzed giant phages have a homologous protease that processes major capsid and portal proteins, processing of ejection proteins is not always a stable/defining feature. Our identification in SPN3US, and related phages, of a diverged paralog to the prohead protease further hints toward a complicated evolutionary pathway for giant phage head structure and assembly. PMID:29187846

  5. Mechanical splicing of superelastic Cu–Al–Mn alloy bars with headed ends

    NASA Astrophysics Data System (ADS)

    Kise, S.; Mohebbi, A.; Saiidi, M. S.; Omori, T.; Kainuma, R.; Shrestha, K. C.; Araki, Y.

    2018-06-01

    This paper examines the feasibility of mechanical splicing using a steel coupler to connect headed ends of superelastic Cu–Al–Mn alloy (Camalloy) bars and steel reinforcing bars to be used in concrete structures. Although threading of Camalloy is as easy as that of steel, mechanical splicing using threaded ends requires machining of Camalloy bars into dog-bone shape to avoid brittle fracture at the threaded ends. The machining process requires significant time and cost and wastes substantial amount of the material. This paper attempts to resolve this issue by applying mechanical splicing using steel couplers to connect headed ends of Camalloy and steel reinforcing bars. To study its feasibility, we prepare 3 specimens wherein both ends of each Camalloy bar (13 mm diameter and 300 mm length) are connected to steel reinforcing bars. The specimens are tested under monotonic, single-cycle, and full-cycle tension loading conditions. From these tests, we observed (1) excellent superelasticity with recoverable strain of around 6% and (2) large ductility with fracture strain of over 19%. It should be emphasized here that, in all the specimens, ductile fracture occurred at the locations apart from the headed ends. This is in sharp contrast with brittle fracture of headed superelastic Ni–Ti SMA bars, most of which took place around the headed ends. From the results of the microstructural analysis, we identified the following reasons for avoiding brittle fracture at the headed ends: (1) Precipitation hardening increases the strength around the boundary between the straight and headed (tapered) portions, where stress concentration takes place. (2) The strength of the straight portion does not increase significantly up to the ductile fracture if its grain orientation is close to 〈0 0 1〉.

  6. Poster — Thur Eve — 59: Atlas Selection for Automated Segmentation of Pelvic CT for Prostate Radiotherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mallawi, A; Farrell, T; Diamond, K

    2014-08-15

    Automated atlas-based segmentation has recently been evaluated for use in planning prostate cancer radiotherapy. In the typical approach, the essential step is the selection of an atlas from a database that best matches the target image. This work proposes an atlas selection strategy and evaluates its impact on the final segmentation accuracy. Prostate length (PL), right femoral head diameter (RFHD), and left femoral head diameter (LFHD) were measured in CT images of 20 patients. Each subject was then taken as the target image to which all remaining 19 images were affinely registered. For each pair of registered images, the overlapmore » between prostate and femoral head contours was quantified using the Dice Similarity Coefficient (DSC). Finally, we designed an atlas selection strategy that computed the ratio of PL (prostate segmentation), RFHD (right femur segmentation), and LFHD (left femur segmentation) between the target subject and each subject in the atlas database. Five atlas subjects yielding ratios nearest to one were then selected for further analysis. RFHD and LFHD were excellent parameters for atlas selection, achieving a mean femoral head DSC of 0.82 ± 0.06. PL had a moderate ability to select the most similar prostate, with a mean DSC of 0.63 ± 0.18. The DSC obtained with the proposed selection method were slightly lower than the maximums established using brute force, but this does not include potential improvements expected with deformable registration. Atlas selection based on PL for prostate and femoral diameter for femoral heads provides reasonable segmentation accuracy.« less

  7. LASIK flap characteristics using the Moria M2 microkeratome with the 90-microm single use head.

    PubMed

    Aslanides, Ioannis M; Tsiklis, Nikolaos S; Astyrakakis, Nikolaos I; Pallikaris, Ioannis G; Jankov, Mirko R

    2007-01-01

    To evaluate the accuracy and consistency of corneal flap thickness, horizontal diameter, and hinge size with the Moria M2 90-microm single use head. Fifty-two myopic patients (104 eyes), mean age 32.6 years, underwent bilateral LASIK with a superior hinged flap using the Moria M2 microkeratome (90-microm single use head). Prospective evaluation included flap thickness (subtraction method), diameter, hinge size, interface particles, intraoperative complications, and visual recovery. The mean preoperative spherical equivalent refraction was -5.72 +/- 2.59 diopters (D) (range: -2.88 to -10.75 D) and -5.84 +/- 2.73 D (range: -3.13 to -9.38 D) for right and left eyes, respectively. The mean preoperative central corneal thickness was 548 +/- 24 microm and 547 +/- 25 microm for right and left eyes, respectively. The mean preoperative steepest K was 44.12 +/- 1.28 D and 44.41 +/- 1.27 D for right and left eyes, respectively. Corneal diameter (white-to-white) was 12 +/- 0.4 mm and 11.9 +/- 0.4 mm for right and left eyes, respectively. The mean postoperative flap thickness was 109 +/- 18 microm (range: 67 to 152 microm) and 103 +/- 15 microm (range: 65 to 151 microm) for right and left eyes, respectively. The mean postoperative flap diameter was 9.4 +/- 0.3 mm (expected mean according to the nomogram given by the company was 9.5 mm). The mean postoperative hinge chord was 4.4 +/- 0.4 mm (expected mean 4.2 mm). No interface particles were detected on slit-lamp examination. The Moria M2 90-microm single use head is safe with reasonable predictability for LASIK flap creation.

  8. Nationwide multicenter follow-up cohort study of hip arthroplasties performed for osteonecrosis of the femoral head.

    PubMed

    Kobayashi, Seneki; Kubo, Toshikazu; Iwamoto, Yukihide; Fukushima, Wakaba; Sugano, Nobuhiko

    2018-05-12

    To identify modifiable factors related to post-operative dislocation and reoperation in patients with osteonecrosis of the femoral head (ONFH) in a large cohort. We studied 4995 hip arthroplasties: total hip arthroplasty (THA) was performed in 79% of patients; bipolar hemiarthroplasty (BP), 17%; total resurfacing arthroplasty (tRS), 3%; and hemi-resurfacing arthroplasty (hRS), 1%. A new type of BP (accounting for 49% of BPs) comprised a femoral component with a polished or smooth, small-diameter (approximately 10 mm) neck with a round or oval axial cut surface and no sharp corners. The infection rate was relatively low (0.56%) even though 58% of cases of ONFH were associated with systemic steroid use, a known risk factor for infection. Post-operative dislocation occurred in 4.3% of cases, with re-operation needed in 3.9%. The dislocation rate was related to surgery type: 5.2% in THA, 0.9% in BP, and 0% in tRS and hRS. Among total arthroplasties with six month or longer follow-up (3670 THAs and 159 tRSs), the risk factors for post-operative dislocation were younger (≤ 40 years) or older (≥ 62 years) age, higher body weight, posterolateral approach, and smaller prosthetic head diameter. Regarding the need for re-operation, higher body weight and surgery type were identified as risk factors. The relatively high dislocation rate of 5.2% in THA is a cause for concern. The identified risk factors for dislocation should be considered when selecting THA for treatment. Prosthesis survivorship in hRSs was inferior to that in BPs or THAs. Body weight also affected the survivorship of hip arthroplasties.

  9. Patterns of fetal growth in a rural Indian cohort and a comparison with a western European population, data from the Pune Maternal Nutrition Study

    PubMed Central

    KINARE, Arun S; CHINCHWADKAR, Manoj C; NATEKAR, Asit S; COYAJI, Kurus J; WILLS, Andrew K; JOGLEKAR, Charudatta V; YAJNIK, Chittaranjan S; FALL, Caroline HD

    2012-01-01

    Objective To describe fetal size in a rural Indian population and compare it with European and urban Indian populations using ultrasound. Methods Participants were from the Pune Maternal Nutrition Study, India. Fetal growth curves were constructed from serial ultrasound scans at ~18, 30 and 36 weeks gestation in 653 singleton pregnancies. Measurements included femur length (FL) and abdominal circumference (AC), and biparietal diameter (BPD) and occipito-frontal diameter (OFD) from which head circumference (HC) was estimated. Measurements were compared with data from a large population-based study in France and a study of urban mothers in Vellore, South India. Results Fetal AC and BPD were smaller than the French reference at 18 weeks gestation (−1.38 SD and −1.30 SD respectively), while FL and HC were more comparable (−0.77 SD and −0.59 SD). The deficit remained similar at 36 weeks for AC (−0.97 SD), FL (−0.43 SD) and HC (−0.52 SD) and increased for BPD (−2.3 SD). Ultrasound at 18 weeks under-estimated gestational age, compared with LMP date, by a median of −1.4 (IQR −4.6, 1.8) days. The Pune fetuses were smaller, even at the 1st scan, than the urban Vellore sample. Conclusions Fetal size is smaller in a rural Indian population than in European or urban Indian populations, even in mid pregnancy. The deficit varied for different fetal measurements; it was greatest for abdominal circumference and biparietal diameter and least for femur length and head circumference. PMID:20103791

  10. Small head size and delayed body weight growth in wild Japanese monkey fetuses after the Fukushima Daiichi nuclear disaster.

    PubMed

    Hayama, Shin-Ichi; Tsuchiya, Moe; Ochiai, Kazuhiko; Nakiri, Sachie; Nakanishi, Setsuko; Ishii, Naomi; Kato, Takuya; Tanaka, Aki; Konno, Fumiharu; Kawamoto, Yoshi; Omi, Toshinori

    2017-06-14

    To evaluate the biological effect of the Fukushima Daiichi nuclear disaster, relative differences in the growth of wild Japanese monkeys (Macaca fuscata) were measured before and after the disaster of 2011 in Fukushima City, which is approximately 70 km from the nuclear power plant, by performing external measurements on fetuses collected from 2008 to 2016. Comparing the relative growth of 31 fetuses conceived prior to the disaster and 31 fetuses conceived after the disaster in terms of body weight and head size (product of the occipital frontal diameter and biparietal diameter) to crown-rump length ratio revealed that body weight growth rate and proportional head size were significantly lower in fetuses conceived after the disaster. No significant difference was observed in nutritional indicators for the fetuses' mothers. Accordingly, radiation exposure could be one factor contributed to the observed growth delay in this study.

  11. Acceleration induced water removal from ear canals.

    NASA Astrophysics Data System (ADS)

    Kang, Hosung; Averett, Katelee; Jung, Sunghwan

    2017-11-01

    Children and adults commonly experience having water trapped in the ear canals after swimming. To remove the water, individuals will shake their head sideways. Since a child's ear canal has a smaller diameter, it requires more acceleration of the head to remove the trapped water. In this study, we theoretically and experimentally investigated the acceleration required to break the surface meniscus of the water in artificial ear canals and hydrophobic-coated glass tubes. In experiments, ear canal models were 3D-printed from a CT-scanned human head. Also, glass tubes were coated with silane to match the hydrophobicity in ear canals. Then, using a linear stage, we measured the acceleration values required to forcefully eject the water from the artificial ear canals and glass tubes. A theoretical model was developed to predict the critical acceleration at a given tube diameter and water volume by using a modified Rayleigh-Taylor instability. Furthermore, this research can shed light on the potential of long-term brain injury and damage by shaking the head to push the water out of the ear canal. This research was supported by National Science Foundation Grant CBET-1604424.

  12. Transverse Cervical Artery: Consistent Anatomical Landmarks and Clinical Experience with Its Use as a Recipient Artery in Complex Head and Neck Reconstruction.

    PubMed

    Tessler, Oren; Gilardino, Mirko S; Bartow, Matthew J; St Hilaire, Hugo; Womac, Daniel; Dionisopoulos, Tassos; Lessard, Lucie

    2017-03-01

    Many head and neck reconstructions occur in patients with extensive history of surgery or radiation treatment. This leads to complicated free flap reconstructions, especially in choosing recipient vessels in a "frozen neck." The transverse cervical artery is an optimal second-line recipient artery in head and neck reconstruction. Seventy-two neck sides in 36 cadavers were dissected, looking for the transverse cervical artery and transverse cervical vein. Anatomical location of these vessels, their diameter, and length were documented. A retrospective analysis on 19 patients who had head and neck reconstruction using the transverse cervical artery as a recipient artery was undertaken as well with regard to outcome of procedures, reason for surgery, previous operations, and use of vein grafts during surgery. The transverse cervical artery was present in 72 of 72 of cadaveric specimens, and was infraclavicular in two of 72 specimens. Transverse cervical artery length ranged from 4.0 to 7.0 cm, and the mean diameter was 2.65 mm. The transverse cervical vein was present in 61 of 72 cadaveric specimens, the length ranged from 4.0 to 7.0 cm, and the mean diameter was 2.90 mm. The transverse cervical artery averaged 33 mm from midline, and branched off the thyrocervical trunk at an average 17 mm superior to the clavicle. Transverse cervical artery stenosis was markedly less in comparison with external carotid artery stenosis. In a 20-year clinical follow-up study, the transverse cervical artery was the recipient artery in 19 patients. A vein graft was used in one patient, and no flap loss occurred in any of the 19 patients. The transverse cervical artery is a reliable and robust option as a recipient artery in free flap head and neck reconstruction.

  13. Thermal neutron flux mapping in a head phantom

    NASA Astrophysics Data System (ADS)

    Lee, C. L.; Zhou, X.-L.; Harmon, J. F.; Bartholomay, R. W.; Harker, Y. D.; Kudchadker, R. J.

    1999-02-01

    Boron neutron capture therapy (BNCT) is a binary cancer treatment modality in which a boron-containing compound is preferentially loaded into a tumor, followed by irradiation by thermal neutrons. In accelerator-based BNCT, neutrons are produced by charged particle-induced reactions such as 7Li(p, n) 7Be. For deeply seated brain tumors, epithermal (1 eV to 10 kev) neutrons are needed to penetrate the skull cap and subsequently thermalize at the tumor location. Cell damage in BNCT is caused by the high linear energy transfer (LET) products from the 10B(n, α) 7Li reaction. Because the cross section for this reaction is of 1/ v character, the dose due to 10B has essentially the same spatial distribution as the thermal neutron flux. A cylindrical acrylic head phantom (15.24 cm diameter by 21.59 cm length) has been constructed to simulate the patient's head and neck, and acrylic spacers of varying width allow placement of small (active sizes: 0.635 cm diameter by 1.27 cm length and 1.5875 cm diameter by 2.54 cm length) BF 3 proportional counters at nearly all radial and axial locations. Measurements of the thermal flux have also been benchmarked with gold and indium foils (bare and cadmium covered), as well as MCNP simulations. Measurement of the thermal neutron flux using these small BF 3 counters is shown to be adequate for experimentally determining the spatial variation of the 10B dose in head phantoms for accelerator-based BNCT.

  14. Design of Tools for Press-countersinking or Dimpling 0.040-inch-thick-24S-T Sheet

    NASA Technical Reports Server (NTRS)

    Templin, R L; Fogwell, J W

    1942-01-01

    A set of dimpling tools was designed for 0.040-inch 24S-T sheet and flush-type rivets 1/8 inch in diameter with 100 degree countersunk heads. The dimples produced under different conditions of pressure, sheet thickness, and drill diameter are presented as cross-sectional photographs magnified 20 times. The most satisfactory values for the dimpling tools were found to be: maximum punch diameter, 0.231 inch; maximum die diameter, 0.223 inch; maximum mandrel diameter, 0.128 inch; dimple angle, 100 degree; punch springback angle, 1 1/2 degree; and die springback angle, 2 degree.

  15. Measurements of characteristic parameters of extremely small cogged wheels with low module by means of low-coherence interferometry

    NASA Astrophysics Data System (ADS)

    Pakula, Anna; Tomczewski, Slawomir; Skalski, Andrzej; Biało, Dionizy; Salbut, Leszek

    2010-05-01

    This paper presents novel application of Low Coherence Interferometry (LCI) in measurements of characteristic parameters as circular pitch, foot diameter, heads diameter, in extremely small cogged wheels (cogged wheel diameter lower than θ=3 mm and module m = 0.15) produced from metal and ceramics. The most interesting issue concerning small diameter cogged wheels occurs during their production. The characteristic parameters of the wheel depend strongly on the manufacturing process and while inspecting small diameter wheels the shrinkage during the cast varies with the slight change of fabrication process. In the paper the LCI interferometric Twyman - Green setup with pigtailed high power light emitting diode, for cogged wheels measurement, is described. Due to its relatively big field of view the whole wheel can be examined in one measurement, without the necessity of numerical stitching. For purposes of small cogged wheel's characteristic parameters measurement the special binarization algorithm was developed and successfully applied. At the end the results of measurement of heads and foot diameters of two cogged wheels obtained by proposed LCI setup are presented and compared with the results obtained by the commercial optical profiler. The results of examination of injection moulds used for fabrication of measured cogged wheels are also presented. Additionally, the value of cogged wheels shrinkage is calculated as a conclusion for obtained results. Proposed method is suitable for complex measurements of small diameter cogged wheels with low module especially when there are no measurements standards for such objects.

  16. Three new species of the Indo-Pacific fish genus Hime (Aulopidae, Aulopiformes), all resembling the type species H. japonica (Günther 1877).

    PubMed

    Gomon, Martin F; Struthers, Carl D

    2015-11-19

    Descriptions of three new species of the aulopid genus Hime from the central and western Pacific and presumably the easternmost Indian Ocean are presented. Hime surrubea sp. nov., confined to the Hawaiian Island region, has been misidentified in species accounts and faunal lists as H. japonica and although resembling it is separable from that species by its shorter caudal peduncle, slightly larger head, larger eye, especially relative to head size, and slightly smaller pectoral and pelvic fins. Hime capitonis sp. nov. is known conclusively only from seamounts off the southern tip of New Caledonia and Vanuatu, and is distinguishable by its distinctively large head (32.3-35.6% SL) and eyes (orbital diameter 10.8-13.0% SL) and relatively few scales between the anus and anal fin origin (7-9). The Indonesian H. caudizoma sp. nov. is so far known from only 8 specimens, acquired in markets in southeastern Lombok and presumably caught nearby in what would be regarded the eastern reaches of the Indian Ocean. The species is recognisable by its dorsal fin of rather uniform moderate height with nearly straight distal margin and 17 rather than 16 rays, none of which is filamentous in either sex, the second penultimate ray rather than anterior rays the longest in males. Like the other two described here, H. caudizoma has among the largest head and eyes of the family. Observations on the dorsal fin form and other features of H. microps Parin & Kotlyar, 1989 are provided based on a large male specimen collected at Rapa Iti, Austral Islands and a re-evaluation of the original description.

  17. [Transhumeral head plasty and massive osteocartilaginous allograft transplantation for the management of large hill-sachs lesions].

    PubMed

    Hart, R; Okál, F; Komzák, M

    2010-10-01

    The aim of this presentation is to inform the medical community about causal therapy (transhumeral head plasty or massive osteochondral allograft transplantation) for large Hill-Sachs lesions which frequently cause failure of anterior stabilisation following ventral shoulder dislocations. Seven men with an average age of 26 years (19 to 33 years) undergoing surgery in 2006 and 2007 were evaluated. The minimum follow-up was 18 months (41 to 18 months). Impressions on more than 30 % of the articular surface, or those whose critical size was larger than one-eighth of the humeral diameter (on CT scan) were taken as indications for surgery. Four patients had had previous surgery for anterior instability and three had a primary procedure. Four men underwent acute surgery and three had elective operations.Trans- humeral head plasty was used in five and massive osteochondral allograft in two patients. In the patients with large lesions in the anterior aspect of the shoulder joint, transhumeral head plasty involving repair of the ventral structures from the anterior approach was indicatedúúú in those with an isolated posterior bony defect, a massive osteochondral allograft was transplanted through the posterior approach. The Constant-Murley score was used to assess clinical status before (not in acute conditions) and after surgery. All patients reported improved clinical status. The average Constant-Murley score at final follow-up was 95.9 points (83-100 points). In the patients not having an acute procedure in whom pre-operative Constant-Murley scores were obtained, the average improvement was by 22.7 points (8 - 37 points). No general surgical complications were recorded. All patients reported subjective satisfaction and willingness to undergo surgery under the same conditions again. A Hill-Sachs lesion is a frequent injury to the humeral head resulting from anterior shoulder dislocation. To distinguish between major and minor defects in terms of clinical significance is essential for the choice of appropriate shoulder treatment. Up to now large lesions have mostly been managed by non-causal techniques affecting shoulder biomechanics. Transhumeral head plasty or transplantation of a massive osteochondral allograft, on the other hand, offers a causal treatment. However, these two methods have rarely been mentioned in the international literature, and usually only as case reports. Transhumeral head plasty and transplantation of a massive osteochondral allograft offer a causal therapy for the management of Hill-Sachs lesions that does not alter shoulder biomechanics. They are not associated with a higher percentage of post-operative complications. Neither technique is more demanding than non-causal procedures. Operations carried out as primary and not as "salvage" procedures restored the function of the shoulder joint to normal. After secondary surgery, occasional shoulder pain may persist as well as its restricted range of motion.

  18. 40 CFR Appendix Viii to Part 85 - Vehicle and Engine Parameters and Specifications

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... pressure. 3. Valves (intake and exhaust). a. Head diameter dimension. b. Valve lifter or actuator type and... diameter dimension. b. Valve lifter or actuator type and valve lash dimension. 5. Camshaft timing. a. Valve... dimension. b. Valve lifter or actuator type and valve lash dimension. 5. Camshaft timing. a. Valve opening...

  19. 40 CFR Appendix Viii to Part 85 - Vehicle and Engine Parameters and Specifications

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... pressure. 3. Valves (intake and exhaust). a. Head diameter dimension. b. Valve lifter or actuator type and... diameter dimension. b. Valve lifter or actuator type and valve lash dimension. 5. Camshaft timing. a. Valve... dimension. b. Valve lifter or actuator type and valve lash dimension. 5. Camshaft timing. a. Valve opening...

  20. Noise in pressure transducer readings produced by variations in solar radiation

    USGS Publications Warehouse

    Cain, S. F.; Davis, G.A.; Loheide, Steven P.; Butler, J.J.

    2004-01-01

    Variations in solar radiation can produce noise in readings from gauge pressure transducers when the transducer cable is exposed to direct sunlight. This noise is a result of insolation-induced heating and cooling of the air column in the vent tube of the transducer cable. A controlled experiment was performed to assess the impact of variations in solar radiation on transducer readings. This experiment demonstrated that insolation-induced fluctuations in apparent pressure head can be as large as 0.03 m. The magnitude of these fluctuations is dependent on cable color, the diameter of the vent tube, and the length of the transducer cable. The most effective means of minimizing insolation-induced noise is to use integrated transducer-data logger units that fit within a well. Failure to address this source of noise can introduce considerable uncertainty into analyses of hydraulic tests when the head change is relatively small, as is often the case for tests in highly permeable aquifers or for tests using distant observation wells.

  1. PET/CT in giant cell arteritis: High 18F-FDG uptake in the temporal, occipital and vertebral arteries.

    PubMed

    Rehak, Z; Vasina, J; Ptacek, J; Kazda, T; Fojtik, Z; Nemec, P

    18 F-FDG PET/CT imaging is useful in patients with fever of unknown origin and can detect giant cell arteritis in extracranial large arteries. However, it is usually assumed that temporal arteries cannot be visualized with a PET/CT scanner due to their small diameter. Three patients with clinical symptoms of temporal arteritis were examined using a standard whole body PET/CT protocol (skull base - mid thighs) followed by a head PET/CT scan using the brain protocol. High 18 F-FDG uptake in the aorta and some arterial branches were detected in all 3 patients with the whole body protocol. Using the brain protocol, head imaging led to detection of high 18 F-FDG uptake in temporal arteries as well as in their branches (3 patients), in occipital arteries (2 patients) and also in vertebral arteries (3 patients). Copyright © 2016 Elsevier España, S.L.U. y SEMNIM. All rights reserved.

  2. Noise in pressure transducer readings produced by variations in solar radiation.

    PubMed

    Cain, Samuel F; Davis, Gregory A; Loheide, Steven P; Butler, James J

    2004-01-01

    Variations in solar radiation can produce noise in readings from gauge pressure transducers when the transducer cable is exposed to direct sunlight. This noise is a result of insolation-induced heating and cooling of the air column in the vent tube of the transducer cable. A controlled experiment was performed to assess the impact of variations in solar radiation on transducer readings. This experiment demonstrated that insolation-induced fluctuations in apparent pressure head can be as large as 0.03 m. The magnitude of these fluctuations is dependent on cable color, the diameter of the vent tube, and the length of the transducer cable. The most effective means of minimizing insolation-induced noise is to use integrated transducer-data logger units that fit within a well. Failure to address this source of noise can introduce considerable uncertainty into analyses of hydraulic tests when the head change is relatively small, as is often the case for tests in highly permeable aquifers or for tests using distant observation wells.

  3. [Tripolar arthroplasty for recurrent total hip prosthesis dislocation].

    PubMed

    Beaulé, P-E; Roussignol, X; Schmalzried, T-P; Udomkiat, P; Amstutz, H-C; Dujardin, F-H

    2003-05-01

    The purpose of this study was to assess the results of revision surgery for recurrent total hip prosthesis dislocation using a tripolar prosthesis composed of a conventional stem with a mobile head of an intermediary prosthesis measuring more than 40 mm and a modified cup. This technique was used in two centers in Rouen France and Los Angeles USA. Twenty-one hips in 21 patients were operated on. The mobile heads measured 40 to 47 mm. Mean patient age was 70 years (range 29-92). The indication for the tripolar prosthesis was reserved for extremely unstable hips in patients with major risk factors for recurrent dislocation. These 21 patients had experienced 95 dislocations. The acetabular cup was custom-made for the large-diameter heads. A cemented polyethylene cup was used in 14 cases and a press-fit metal-backed around a polyethylene insert in 7. The polyethylene thickness varied from 6.5 to 16 mm for the cemented cups and 4 to 5 mm for the press-fit cups. Fourteen femoral stems were left in place as were two press-fit cups where only the inserts were changed. Mean follow-up was 5.4 years (range 3-11.8). There has been no recurrent dislocation for 20 hips. One patient experienced a dislocation one week after surgery which required a second revision procedure to reposition the acetabular implant. Final outcome was good at 7.6 years for this hip. One patient who had not had any recurrent dislocation died 4 years after the revision surgery due to a cause unrelated to the prosthesis. Two patients were lost to follow-up at 3.7 and 6 years, both were pain free and had no radiological anomalies. Infection occurred in one patient undergoing chemotherapy for a myeloma; the head and neck had to be resected. For the 20 other patients, functional outcome, assessed with the UCLA score, showed improvement in pain (5.8 preoperatively, 9.2 at last follow-up), walking (4.8 and 8 respectively), function (4 and 6 respectively), and daily activities (3.3 and 5.2 respectively). A revision procedure was necessary for one patient during the 4(th) year because of a fracture of the polyethylene insert on a metal-back cup; the insert alone was changed. Excepting the patient with infection, there were no cases of certain or probable loosening during the follow-up. The tripolar prosthesis with a mobile cup and a large-diameter head appears to be a reliable solution for these severely unstable hips. The procedure can often be limited to the acetabular component, reducing morbidity. The thickness of the polyethylene cup is a limitation which may affect long-term survival. Search for a highly wear-resistant couple continues.

  4. Research on the cavitation characteristic of Kaplan turbine under sediment flow condition

    NASA Astrophysics Data System (ADS)

    Weili, L.; Jinling, L.; Xingqi, L.; Yuan, L.

    2010-08-01

    The sediment concentration in many rivers in our world is very high, and the Kaplan turbine running in these rivers are usually seriously abraded. Since the existence of sand, the probability of cavitation is greatly enhanced. Under the joint action and mutual promotion of cavitation and sand erosion, serious abrasion could be made, the hydraulic performance of the Kaplan turbine may be descended, and the safety and stability of turbine are greatly threatened. Therefore, it is very important and significant to investigate the cavitation characteristic of Kaplan turbine under sediment flow condition. In this paper, numerical simulation of cavitation characteristic in pure water and solid-liquid two-phase flow in Kaplan turbine was performed. The solid-liquid two-fluid model were adopted in the numerical simulation, and the pressure, velocity and particle concentration distributive regularity on turbine blade surface under different diameter and concentration was revealed. Particle trajectory model was used to investigate the region and degree of runner blade abrasion in different conditions. The results showed that serious sand abrasion could be found near the blade head and outlet in large flow rate working condition. Relatively slight abrasion may be found near blade flange in small flow rate working condition. The more the sediment concentration and the large the sand diameter, the serious the runner is abraded, and the greater the efficiency is decreased. further analysis of the combined effects of wear and abrasion was performed. The result shows that the cavitation in silt flow is more serious than in pure water. The runner cavitation performance become worse under high sand concentration and large particle diameter, and the efficiency decrease greatly with the increase of sediment concentration.

  5. Bend measurement using an etched fiber incorporating a fiber Bragg grating.

    PubMed

    Rauf, Abdul; Zhao, Jianlin; Jiang, Biqiang; Jiang, Yajun; Jiang, Wei

    2013-01-15

    A fiber Bragg grating (FBG) based bend measurement method using an etched fiber is proposed that utilizes the coupling of the core mode to the cladding and radiation modes at the bending region. An etching region of 99 µm diameter that serves as bend sensing head is achieved at 10 mm upstream the FBG through processing in 40% hydrofluoric acid, while the FBG acts as a narrowband reflector to enhance the sensitivity. The power variation curves are obtained for a wide range of bend angles, but the performance is limited due to the presence of the loss peaks. The sensing response is improved by immersing the etching region in a refractive index matching gel. The results are analyzed by using curve fitting formulas and are in good agreement. A large dynamic range of -27° to +27° and sensitivity of 0.43 dBm/deg is achieved, which can be enhanced by reducing the etched diameter.

  6. Implementation of pressurized air injection system in a Kaplan prototype for the reduction of vibration caused by tip vortex cavitation

    NASA Astrophysics Data System (ADS)

    Rivetti, A.; Angulo, M.; Lucino, C.; Hene, M.; Capezio, O.; Liscia, S.

    2016-11-01

    Blade tip cavitation is a well-known phenomenon that affects the performance of large-diameter Kaplan turbines and induces structural vibration. Injection of pressurized air has been found to yield promising results in reducing those damaging effects. In this work, the results of an experimental test of air injection on a 9.5-m-diameter Kaplan turbine are reported. Experiments were performed for several load conditions and for two different net heads. Accelerations, pressure pulsation and noise emission were monitored for every tested condition. Results show that, at the expense of a maximum efficiency drop of 0.2%, air injection induces a decrease on the level of vibration from 57% up to 84%, depending on the load condition. Such decrease is seen to be proportional to the air flow rate, in the range from 0.06 to 0.8‰ (respect to the discharge at the best efficiency point).

  7. Large shield volcanos on Venus: The effect of neutral buoyancy zone development on evolution and altitude distribution

    NASA Technical Reports Server (NTRS)

    Keddie, S.; Head, James W., III

    1992-01-01

    The Magellan mission to Venus has emphasized the importance of volcanism in shaping the surface of the planet. Volcanic plains make up 80 percent of the terrain and hundreds of regions of localized eruptions have been identified. Large volcanos, defined as edifices with diameters greater than 100 km, are the sites of some of the most voluminous eruptions. Head et al. have identified 158 of these structures. Their spatial distribution is neither random nor arranged in linear chains as on the Earth; large volcanos on Venus are concentrated in two large, near-equatorial clusters that are also the site of many other forms of volcanic activity. The set of conditions that must be met on Venus that controls the change from widespread, distributed volcanism to focused, shield-building volcanism is not well understood. Future studies of transitional features will help to address this problem. It is likely, however, that the formation and evolution of a neutral buoyancy zone (NBZ) plays an important role in both determining the style of the volcanism and the development of the volcanic feature once it has begun to erupt. Head and Wilson have suggested that the high surface pressure on Venus may inhibit volatile exsolution, which may influence the density distribution of the upper crust and hence control the nature and location of a NBZ. The extreme variations in pressure with elevation may result in significantly different characteristics of such a NBZ at different locations on the planet. In order to test these ideas regarding the importance of NBZ development in the evolution of a large shield and to determine the style of volcanism, three large volcanos that occur at different basal elevations were examined and the distribution of large volcanos as a function of altitude was determined.

  8. Maternal pelvic dimensions and neonatal size: Implications for growth plasticity in early life as adaptation.

    PubMed

    Wells, Jonathan C K; Figueiroa, José N; Alves, Joao G

    2017-01-01

    Patterns of fetal growth predict non-communicable disease risk in adult life, but fetal growth variability appears to have a relatively weak association with maternal nutritional dynamics during pregnancy. This challenges the interpretation of fetal growth variability as 'adaptation'. We hypothesized that associations of maternal size and nutritional status with neonatal size are mediated by the dimensions of the maternal pelvis. We analysed data on maternal height, body mass index (BMI) and pelvic dimensions (conjugate, inter-spinous and inter-cristal diameters) and neonatal gestational age, weight, length, thorax girth and head girth ( n = 224). Multiple regression analysis was used to identify independent maternal predictors of neonatal size, and the mediating role of neonatal head girth in these associations. Pelvic dimensions displaced maternal BMI as a predictor of birth weight, explaining 11.6% of the variance. Maternal conjugate and inter-spinous diameters predicted neonatal length, thorax girth and head girth, whereas inter-cristal diameter only predicted neonatal length. Associations of pelvic dimensions with birth length, but not birth weight, were mediated by neonatal head girth. Pelvic dimensions predicted neonatal size better than maternal BMI, and these associations were mostly independent of maternal height. Sensitivity of fetal growth to pelvic dimensions reduces the risk of cephalo-pelvic disproportion, potentially a strong selective pressure during secular trends in height. Selection on fetal adaptation to relatively inflexible components of maternal phenotype, rather than directly to external ecological conditions, may help explain high levels of growth plasticity during late fetal life and early infancy.

  9. Determination of sex from radiographic measurements of the humerus by discriminant function analysis in Saudi population, Qassim region, KSA.

    PubMed

    Shehri, Fahad Al; Soliman, Khaled E A

    2015-08-01

    Diagnosis of sex from skeleton or individual bone plays an important role in identifying unknown bodies, parts of bodies or skeletal remains for forensic purposes. This study aims to examine the applicability of the measurements taken from the humerus to assess sex, and to contribute to establishing discriminant function equations for Saudi populations for medico legal applications. Archived X-ray radiographs of humerus for 387 patients (216 males & 171 females) who attended the orthopedic clinics at Suleiman Al-Habib Hospital, Qassim region, KSA in the period from January 2011 to December 2013 were reviewed and analyzed. Five dimensions, including maximum length, vertical head diameter, diameter of head+greater tubercle, right-left diameter at midshaft, and epicondylar breadth were taken and subjected to Univariate and multivariate discriminant function analysis. The studied radiographic dimensions of the humerus indicate that there are significant differences (p<0.05) between the males and females measurements while the difference between right and left measurements was not significant. The findings revealed that the proximal part of the humerus has greater diagnostic accuracy than distal and middle parts. Accuracy of correct classification varies between 68.0% (epicondylar breadth) and 90.4% (vertical head diameter) for univariate analyses. When the multivariate analyses were conducted, three functions were produced, with the accuracy of ranging between 88.4% and 94.3%. These findings suggested that the dimensions of the humerus, especially the measurements taken from the proximal parts, could be used successfully for sex diagnosis. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  10. 9.4T Human MRI: Preliminary Results

    PubMed Central

    Vaughan, Thomas; DelaBarre, Lance; Snyder, Carl; Tian, Jinfeng; Akgun, Can; Shrivastava, Devashish; Liu, Wanzahn; Olson, Chris; Adriany, Gregor; Strupp, John; Andersen, Peter; Gopinath, Anand; van de Moortele, Pierre-Francois; Garwood, Michael; Ugurbil, Kamil

    2014-01-01

    This work reports the preliminary results of the first human images at the new high-field benchmark of 9.4T. A 65-cm-diameter bore magnet was used together with an asymmetric 40-cm-diameter head gradient and shim set. A multichannel transmission line (transverse electromagnetic (TEM)) head coil was driven by a programmable parallel transceiver to control the relative phase and magnitude of each channel independently. These new RF field control methods facilitated compensation for RF artifacts attributed to destructive interference patterns, in order to achieve homogeneous 9.4T head images or localize anatomic targets. Prior to FDA investigational device exemptions (IDEs) and internal review board (IRB)-approved human studies, preliminary RF safety studies were performed on porcine models. These data are reported together with exit interview results from the first 44 human volunteers. Although several points for improvement are discussed, the preliminary results demonstrate the feasibility of safe and successful human imaging at 9.4T. PMID:17075852

  11. Cranial diameter pulsations measured by non-invasive ultrasound decrease with tilt

    NASA Technical Reports Server (NTRS)

    Ueno, Toshiaki; Ballard, Richard E.; Macias, Brandon R.; Yost, William T.; Hargens, Alan R.

    2003-01-01

    INTRODUCTION: Intracranial pressure (ICP) may play a significant role in physiological responses to microgravity by contributing to the nausea associated with microgravity exposure. However, effects of altered gravity on ICP in astronauts have not been investigated, primarily due to the invasiveness of currently available techniques. We have developed an ultrasonic device that monitors changes in cranial diameter pulsation non-invasively so that we can evaluate ICP dynamics in astronauts during spaceflight. This study was designed to demonstrate the feasibility of our ultrasound technique under the physiological condition in which ICP dynamics are changed due to altered gravitational force. METHODS: Six healthy volunteers were placed at 60 degrees head-up, 30 degrees headup, supine, and 15 degrees head-down positions for 3 min at each angle. We measured arterial blood pressure (ABP) with a finger pressure cuff, and cranial diameter pulsation with a pulsed phase lock loop device (PPLL). RESULTS: Analysis of covariance demonstrated that amplitudes of cranial diameter pulsations were significantly altered with the angle of tilt (p < 0.001). The 95% confidence interval for linear regression coefficients of the cranial diameter pulsation amplitudes with tilt angle was 0.862 to 0.968. However, ABP amplitudes did not show this relationship. DISCUSSION: Our noninvasive ultrasonic technique reveals that the amplitude of cranial diameter pulsation decreases as a function of tilt angle, suggesting that ICP pulsation follows the same relationship. It is demonstrated that the PPLL device has a sufficient sensitivity to detect changes non-invasively in ICP pulsation caused by altered gravity.

  12. Eye Size at Birth in Prosimian Primates: Life History Correlates and Growth Patterns

    PubMed Central

    Cummings, Joshua R.; Muchlinski, Magdalena N.; Kirk, E. Christopher; Rehorek, Susan J.; DeLeon, Valerie B.; Smith, Timothy D.

    2012-01-01

    Background Primates have large eyes relative to head size, which profoundly influence the ontogenetic emergence of facial form. However, growth of the primate eye is only understood in a narrow taxonomic perspective, with information biased toward anthropoids. Methodology/Principal Findings We measured eye and bony orbit size in perinatal prosimian primates (17 strepsirrhine taxa and Tarsius syrichta) to infer the extent of prenatal as compared to postnatal eye growth. In addition, multiple linear regression was used to detect relationships of relative eye and orbit diameter to life history variables. ANOVA was used to determine if eye size differed according to activity pattern. In most of the species, eye diameter at birth measures more than half of that for adults. Two exceptions include Nycticebus and Tarsius, in which more than half of eye diameter growth occurs postnatally. Ratios of neonate/adult eye and orbit diameters indicate prenatal growth of the eye is actually more rapid than that of the orbit. For example, mean neonatal transverse eye diameter is 57.5% of the adult value (excluding Nycticebus and Tarsius), compared to 50.8% for orbital diameter. If Nycticebus is excluded, relative gestation age has a significant positive correlation with relative eye diameter in strepsirrhines, explaining 59% of the variance in relative transverse eye diameter. No significant differences were found among species with different activity patterns. Conclusions/Significance The primate developmental strategy of relatively long gestations is probably tied to an extended period of neural development, and this principle appears to apply to eye growth as well. Our findings indicate that growth rates of the eye and bony orbit are disassociated, with eyes growing faster prenatally, and the growth rate of the bony orbit exceeding that of the eyes after birth. Some well-documented patterns of orbital morphology in adult primates, such as the enlarged orbits of nocturnal species, mainly emerge during postnatal development. PMID:22567127

  13. Three-dimensional MRI Analysis of Femoral Head Remodeling After Reduction in Patients With Developmental Dysplasia of the Hip.

    PubMed

    Tsukagoshi, Yuta; Kamada, Hiroshi; Kamegaya, Makoto; Takeuchi, Ryoko; Nakagawa, Shogo; Tomaru, Yohei; Tanaka, Kenta; Onishi, Mio; Nishino, Tomofumi; Yamazaki, Masashi

    2018-05-02

    Previous reports on patients with developmental dysplasia of the hip (DDH) showed that the prereduced femoral head was notably smaller and more nonspherical than the intact head, with growth failure observed at the proximal posteromedial area. We evaluated the shape of the femoral head cartilage in patients with DDH before and after reduction, with size and sphericity assessed using 3-dimensional (3D) magnetic resonance imaging (MRI). We studied 10 patients with unilateral DDH (all female) who underwent closed reduction. Patients with avascular necrosis of the femoral head on the plain radiograph 1 year after reduction were excluded. 3D MRI was performed before reduction and after reduction, at 2 years of age. 3D-image analysis software was used to reconstruct the multiplanes. After setting the axial, coronal, and sagittal planes in the software (based on the femoral shaft and neck axes), the smallest sphere that included the femoral head cartilage was drawn, the diameter was measured, and the center of the sphere was defined as the femoral head center. We measured the distance between the center and cartilage surface every 30 degrees on the 3 reconstructed planes. Sphericity of the femoral head was calculated using a ratio (the distance divided by each radius) and compared between prereduction and postreduction. The mean patient age was 7±3 and 26±3 months at the first and second MRI, respectively. The mean duration between the reduction and second MRI was 18±3 months. The femoral head diameter was 26.7±1.5 and 26.0±1.6 mm on the diseased and intact sides, respectively (P=0.069). The ratios of the posteromedial area on the axial plane and the proximoposterior area on the sagittal plane after reduction were significantly larger than before reduction (P<0.01). We demonstrated that the size of the reduced femoral head was nearly equal to that of the intact femoral head and that the growth failure area of the head before reduction, in the proximal posteromedial area, was remodeled after reduction. Level IV-case series.

  14. Shaping of Looped Miniaturized Chalcogenide Fiber Sensing Heads for Mid-Infrared Sensing

    PubMed Central

    Houizot, Patrick; Anne, Marie-Laure; Boussard-Plédel, Catherine; Loréal, Olivier; Tariel, Hugues; Lucas, Jacques; Bureau, Bruno

    2014-01-01

    Chalcogenide glass fibers are promising photonic tools to develop Fiber Evanescent Wave Spectroscopy (FEWS) optical sensors working in the mid-infrared region. Numerous pioneering works have already been carried out showing their efficiency, especially for bio-medical applications. Nevertheless, this technology remains confined to academic studies at the laboratory scale because chalcogenide glass fibers are difficult to shape to produce reliable, sensitive and compact sensors. In this paper, a new method for designing and fabricating a compact and robust sensing head with a selenide glass fiber is described. Compact looped sensing heads with diameter equal to 2 mm were thus shaped. This represents an outstanding achievement considering the brittleness of such uncoated fibers. FEWS experiments were implemented using alcoholic solutions as target samples showing that the sensitivity is higher than with the routinely used classical fiber. It is also shown that the best compromise in term of sensitivity is to fabricate a sensing head including two full loops. From a mechanical point of view, the breaking loads of the loop shaped head are also much higher than with classical fiber. Finally, this achievement paves the way for the use of mid-infrared technology during in situ and even in vivo medical operations. Indeed, is is now possible to slide a chalcogenide glass fiber in the operating channel of a standard 2.8 mm diameter catheter. PMID:25264953

  15. Twentieth-century decline of large-diameter trees in Yosemite National Park, California, USA

    USGS Publications Warehouse

    Lutz, J.A.; van Wagtendonk, J.W.; Franklin, J.F.

    2009-01-01

    Studies of forest change in western North America often focus on increased densities of small-diameter trees rather than on changes in the large tree component. Large trees generally have lower rates of mortality than small trees and are more resilient to climate change, but these assumptions have rarely been examined in long-term studies. We combined data from 655 historical (1932-1936) and 210 modern (1988-1999) vegetation plots to examine changes in density of large-diameter trees in Yosemite National Park (3027 km2). We tested the assumption of stability for large-diameter trees, as both individual species and communities of large-diameter trees. Between the 1930s and 1990s, large-diameter tree density in Yosemite declined 24%. Although the decrease was apparent in all forest types, declines were greatest in subalpine and upper montane forests (57.0% of park area), and least in lower montane forests (15.3% of park area). Large-diameter tree densities of 11 species declined while only 3 species increased. Four general patterns emerged: (1) Pinus albicaulis, Quercus chrysolepis, and Quercus kelloggii had increases in density of large-diameter trees occur throughout their ranges; (2) Pinus jeffreyi, Pinus lambertiana, and Pinus ponderosa, had disproportionately larger decreases in large-diameter tree densities in lower-elevation portions of their ranges; (3) Abies concolor and Pinus contorta, had approximately uniform decreases in large-diameter trees throughout their elevational ranges; and (4) Abies magnifica, Calocedrus decurrens, Juniperus occidentalis, Pinus monticola, Pseudotsuga menziesii, and Tsuga mertensiana displayed little or no change in large-diameter tree densities. In Pinus ponderosa-Calocedrus decurrens forests, modern large-diameter tree densities were equivalent whether or not plots had burned since 1936. However, in unburned plots, the large-diameter trees were predominantly A. concolor, C. decurrens, and Q. chrysolepis, whereas P. ponderosa dominated the large-diameter component of burned plots. Densities of large-diameter P. ponderosa were 8.1 trees ha-1 in plots that had experienced fire, but only 0.5 trees ha-1 in plots that remained unburned. ?? 2009 Elsevier B.V. All rights reserved.

  16. Ultrastructure of Dendritic Spines: Correlation Between Synaptic and Spine Morphologies

    PubMed Central

    Arellano, Jon I.; Benavides-Piccione, Ruth; DeFelipe, Javier; Yuste, Rafael

    2007-01-01

    Dendritic spines are critical elements of cortical circuits, since they establish most excitatory synapses. Recent studies have reported correlations between morphological and functional parameters of spines. Specifically, the spine head volume is correlated with the area of the postsynaptic density (PSD), the number of postsynaptic receptors and the ready-releasable pool of transmitter, whereas the length of the spine neck is proportional to the degree of biochemical and electrical isolation of the spine from its parent dendrite. Therefore, the morphology of a spine could determine its synaptic strength and learning rules. To better understand the natural variability of neocortical spine morphologies, we used a combination of gold-toned Golgi impregnations and serial thin-section electron microscopy and performed three-dimensional reconstructions of spines from layer 2/3 pyramidal cells from mouse visual cortex. We characterized the structure and synaptic features of 144 completed reconstructed spines, and analyzed their morphologies according to their positions. For all morphological parameters analyzed, spines exhibited a continuum of variability, without clearly distinguishable subtypes of spines or clear dependence of their morphologies on their distance to the soma. On average, the spine head volume was correlated strongly with PSD area and weakly with neck diameter, but not with neck length. The large morphological diversity suggests an equally large variability of synaptic strength and learning rules. PMID:18982124

  17. Invertebrate muscles: thin and thick filament structure; molecular basis of contraction and its regulation, catch and asynchronous muscle

    PubMed Central

    Hooper, Scott L.; Hobbs, Kevin H.; Thuma, Jeffrey B.

    2008-01-01

    This is the second in a series of canonical reviews on invertebrate muscle. We cover here thin and thick filament structure, the molecular basis of force generation and its regulation, and two special properties of some invertebrate muscle, catch and asynchronous muscle. Invertebrate thin filaments resemble vertebrate thin filaments, although helix structure and tropomyosin arrangement show small differences. Invertebrate thick filaments, alternatively, are very different from vertebrate striated thick filaments and show great variation within invertebrates. Part of this diversity stems from variation in paramyosin content, which is greatly increased in very large diameter invertebrate thick filaments. Other of it arises from relatively small changes in filament backbone structure, which results in filaments with grossly similar myosin head placements (rotating crowns of heads every 14.5 nm) but large changes in detail (distances between heads in azimuthal registration varying from three to thousands of crowns). The lever arm basis of force generation is common to both vetebrates and invertebrates, and in some invertebrates this process is understood on the near atomic level. Invertebrate actomyosin is both thin (tropomyosin:troponin) and thick (primarily via direct Ca++ binding to myosin) filament regulated, and most invertebrate muscles are dually regulated. These mechanisms are well understood on the molecular level, but the behavioral utility of dual regulation is less so. The phosphorylation state of the thick filament associated giant protein, twitchin, has been recently shown to be the molecular basis of catch. The molecular basis of the stretch activation underlying asynchronous muscle activity, however, remains unresolved. PMID:18616971

  18. Ontogenetic Development of Vestibulo-Ocular Reflexes in Amphibians

    PubMed Central

    Branoner, Francisco; Chagnaud, Boris P.; Straka, Hans

    2016-01-01

    Vestibulo-ocular reflexes (VOR) ensure gaze stability during locomotion and passively induced head/body movements. In precocial vertebrates such as amphibians, vestibular reflexes are required very early at the onset of locomotor activity. While the formation of inner ears and the assembly of sensory-motor pathways is largely completed soon after hatching, angular and translational/tilt VOR display differential functional onsets and mature with different time courses. Otolith-derived eye movements appear immediately after hatching, whereas the appearance and progressive amelioration of semicircular canal-evoked eye movements is delayed and dependent on the acquisition of sufficiently large semicircular canal diameters. Moreover, semicircular canal functionality is also required to tune the initially omnidirectional otolith-derived VOR. The tuning is due to a reinforcement of those vestibulo-ocular connections that are co-activated by semicircular canal and otolith inputs during natural head/body motion. This suggests that molecular mechanisms initially guide the basic ontogenetic wiring, whereas semicircular canal-dependent activity is required to establish the spatio-temporal specificity of the reflex. While a robust VOR is activated during passive head/body movements, locomotor efference copies provide the major source for compensatory eye movements during tail- and limb-based swimming of larval and adult frogs. The integration of active/passive motion-related signals for gaze stabilization occurs in central vestibular neurons that are arranged as segmentally iterated functional groups along rhombomere 1–8. However, at variance with the topographic maps of most other sensory systems, the sensory-motor transformation of motion-related signals occurs in segmentally specific neuronal groups defined by the extraocular motor output targets. PMID:27877114

  19. A Comparison of the Size Frequency Distributions of the Quasi-circular Flat-floor Depression Structures on Comet 67P/Churyumov-Gerasimenko and Comet Wild 2

    NASA Astrophysics Data System (ADS)

    Ip, Wing-Huen; Li, Yuan; Lin, Zhong-Yi; Lee, Jui-chi; Besse, Sebastien; Vincent, Jean-Baptiste; Pajola, Maurizio; Gabriele, Cremonese; Alice, Lucchetti

    2015-04-01

    The close-up views of comet 67P/Churyumov-Gerasimenko by the OSIRIS camera system on board Rosetta have shown that the nucleus structure can be broadly divided into three parts: head, body and neck (Sierks et al., 2015; Thomas et al., 2015). The surfaces of the head and body are covered by near-circular flat-floor depression structures (or pits). The relatively large diameter-to-depth ratios do not follow the pattern of impact craters. Some of these structures are embedded with sinkholes characterized by active outgassing in the form of dust jets (Vincent et al., 2015). The largest structure with a diameter of about one km - if of the same physical nature - is located at the tip of the head in Hamehit. Such steep-walled and flat-floored depressions have also been found on comet 81P/Wild 2 by Stardust in the 2004 encounter (Brownlee et al., 2004). The size frequency distributions of these surface structures are similar even though they have different power-law behaviors. This comparative study suggests the interesting possibility that the flat-floored depressions on both comets could have similar origin and evolutionary history. From a comparison of the size frequency distributions of the impact craters on the Martian moons, Phobos and Deimos, and the Saturnian icy moon, Phoebe, with that of comet Wild 2, Cheng et al. (2013) proposed that erosion/subsidence process of impact craters due to active outgassing could be at play in the modification of the original diameter-depth relation to the present flat-floored structure. Floor collapse of a deep-seated cavity filled with volatile ice is another alternative mechanism (Vincent et al., 2015). Because the bulk density of comet 67P is only 470+/-45 kg/m3, its interior must be highly porous. It remains to be investigated how would such porous structure be related to the quasi-circular depression features (Marchi et al., 2015). References: Brownlee, D. et al., (2004), Science,304, 1764-1769. Cheng, A.F. et al. (2013) Icarus, 222, 808-817. Machi, S. et al. (2015) LPSC abstract, in press. Sierks, H. et al. (2015) Science, in press. Thomas, N. et al. (2015) Science, in press. Vincent, J.-B. et al. (2015) Science, submitted.

  20. Habitat use of woodpeckers in the Big Woods of eastern Arkansas

    USGS Publications Warehouse

    Krementz, David G.; Lehnen, Sarah E.; Luscier, J.D.

    2012-01-01

    The Big Woods of eastern Arkansas contain some of the highest densities of woodpeckers recorded within bottomland hardwood forests of the southeastern United States. A better understanding of habitat use patterns by these woodpeckers is a priority for conservationists seeking to maintain these high densities in the Big Woods and the Lower Mississippi Alluvial Valley as a whole. Hence, we used linear mixed-effects and linear models to estimate the importance of habitat characteristics to woodpecker density in the Big Woods during the breeding seasons of 2006 and 2007 and the winter of 2007. Northern flicker Colaptes auratus density was negatively related to tree density both for moderate (. 25 cm diameter at breast height) and larger trees (>61 cm diameter at breast height). Red-headed woodpeckers Melanerpes erythrocephalus also had a negative relationship with density of large (. 61 cm diameter at breast height) trees. Bark disfiguration (an index of tree health) was negatively related to red-bellied woodpecker Melanerpes carolinus and yellow-bellied sapsucker Sphyrapicus varius densities. No measured habitat variables explained pileated woodpecker Dryocopus pileatus density. Overall, the high densities of woodpeckers observed in our study suggest that the current forest management of the Big Woods of Arkansas is meeting the nesting, roosting, and foraging requirements for these birds.

  1. Sex determination from the radius and ulna in a modern South African sample.

    PubMed

    Barrier, I L O; L'Abbé, E N

    2008-07-18

    With a large number of unidentified skeletal remains found in South Africa, the development of population specific osteometric standards is imperative. Forensic anthropologists need to have access to a variety of techniques to establish accurate demographic profiles from complete, fragmentary and/or commingled remains. No research has been done on the forearm of African samples, even though these bones have been shown to exhibit sexual dimorphism. The purpose of this paper is to develop discriminant function formulae to determine sex from the radius and ulna in a South African population. The sample consisted of 200 male and 200 female skeletons from the Pretoria Bone (University of Pretoria) and Raymond A. Dart (Witwatersrand University) collections. Sixteen standard anthropometric measurements were taken from the radius (9) and ulna (7) and subjected to stepwise and direct discriminant function analysis. Distal breadth, minimum mid-shaft diameter and maximum head diameter were the best discriminators of sex for the radius, while minimum mid-shaft diameter and olecranon breadth were selected for the ulna. Classification accuracy for the forearm ranged from 76 to 86%. The radius and ulna can be considered moderate discriminators for determining sex in a South African group. However, it is advised that these formulae are used in conjunction with additional methods to determine sex.

  2. [Bilateral caudate head infarcts].

    PubMed

    Kuriyama, N; Yamamoto, Y; Akiguchi, I; Oiwa, K; Nakajima, K

    1997-11-01

    We reported a 67-year-old woman with bilateral caudate head infarcts. She developed sudden mutism followed by abulia. She was admitted to our hospital 2 months after ictus for further examination. She showed prominent abulia and was inactive, slow and apathetic. Spontaneous activity and speech, immediate response to queries, spontaneous word recall and attention and persistence to complex programs were disturbed. Apparent motor disturbance, gait disturbance, motor aphasia, apraxia and remote memory disturbance were not identified. She seemed to be depressed but not sad. Brain CT and MRI revealed bilateral caudate head hemorrhagic infarcts including bilateral anterior internal capsules, in which the left lesion was more extensive than right one and involved the part of the left putamen. These infarct locations were thought to be supplied by the area around the medial striate artery including Heubner's arteries and the A1 perforator. Digital subtraction angiography showed asymptomatic right internal carotid artery occlusion. She bad had hypertension, diabetes mellitus and atrial fibrillation and also had a left atrium with a large diameter. The infarcts were thought to be caused by cardioembolic occlusion to the distal portion of the left internal carotid artery. Although some variations of vasculature at the anterior communicating artery might contribute to bilateral medial striate artery infarcts, we could not demonstrate such abnormalities by angiography. Bilateral caudate head infarcts involving the anterior internal capsule may cause prominent abulia. The patient did not improve by drug and rehabilitation therapy and died suddenly a year after discharge.

  3. Metal-on-metal hip joint tribology.

    PubMed

    Dowson, D; Jin, Z M

    2006-02-01

    The basic tribological features of metal-on-metal total hip replacements have been reviewed to facilitate an understanding of the engineering science underpinning the renaissance of these hard-on-hard joints. Metal-on-polymer hip replacements operate in the boundary lubrication regime, thus leading to the design guidance to reduce the femoral head diameter as much as is feasible to minimize frictional torque and volumetric wear. This explains why the gold-standard implant of this form from the past half-century had a diameter of only 22.225 mm (7/8 in). Metal-on-metal implants can operate in the mild mixed lubrication regime in which much of the applied load is supported by elastohydrodynamic films. Correct tribological design leads to remarkably low steady state wear rates. Promotion of the most effective elastohydrodynamic films calls for the largest possible head diameters and the smallest clearances that can reasonably be adopted, consistent with fine surface finishes, good sphericity and minimal structural elastic deformation of the cup on its foundations. This guidance, which is opposite in form to that developed for metal-on-polymer joints, is equally valid for solid (monolithic) metallic heads on metallic femoral stems and surface replacement femoral shells. Laboratory measurements of friction and wear in metal-on-metal joints have confirmed their potential to achieve a very mild form of mixed lubrication. The key lies in the generation of effective elastohydrodynamic lubricating films of adequate thickness compared with the composite roughness of the head and cup. The calculation of the film thickness is by no means easy, but the full procedure is outlined and the use of an empirical formula that displays good agreement with calculations based upon the full numerical solutions is explained. The representation of the lambda ratio, lambda, embracing both film thickness and composite roughness, is described.

  4. Ridge sowing of sunflower (Helianthus annuus L.) in a minimum till system improves the productivity, oil quality, and profitability on a sandy loam soil under an arid climate.

    PubMed

    Sher, Ahmad; Suleman, Muhammad; Qayyum, Abdul; Sattar, Abdul; Wasaya, Allah; Ijaz, Muhammad; Nawaz, Ahmad

    2018-04-01

    Sunflower (Helianthus annuus L.) is a major oilseed crop grown for its edible oil across the globe including Pakistan. In Pakistan, the production of edible oil is less than the required quantity; the situation is being worsened with the increasing population. Thus, there is dire need to grow those sunflower genotypes which perform better under a given set of agronomic practices. In this 2-year study, we compared four sunflower genotypes, viz., Armoni, Kundi, Sinji, and S-278 for their yield potential, oil contents, fatty acid composition, and profitability under three sowing methods, viz., bed sowing, line sowing, and ridge sowing and two tillage system, viz., plow till and minimum till. Among the sunflower genotypes, the genotype Armoni produced the highest plant height, number of leaves, head diameter, 1000-achene weight, and achene yield; the oil contents and oleic acid were the highest in genotype Sinji. Among the sowing methods, the highest number of leaves per plant, head diameter, number of achenes per head, achene yield, and oil contents were recorded in ridge sowing. Among the tillage systems, the highest head diameter 16. 2 cm, 1000-achene weight (57.2 g), achene yield (1.8 t ha -1 ), oil contents (35.2%), and oleic acid (15.2%) were recorded in minimum till sunflower. The highest net benefits and benefit to cost ratio were recorded in minimum till ridge sown Armoni genotype. In conclusion, the genotype Armoni should be grown on ridges to achieve the highest achene yield, oil contents, and net profitability.

  5. Discrepancy in fetal head biometry between ultrasound and MRI in suspected microcephalic fetuses.

    PubMed

    Yaniv, Gal; Katorza, Eldad; Tsehmaister Abitbol, Vered; Eisenkraft, Arik; Bercovitz, Ronen; Bader, Salim; Hoffmann, Chen

    2017-12-01

    Background Microcephaly is one of the most common fetal structural abnormalities, and prenatal microcephaly is considered a group I malformation of cortical development diagnosed according to ultrasound (US) skull measurements. Purpose To evaluate the agreement between fetal head US and magnetic resonance imaging (MRI) biometric measurements of suspected microcephalic fetuses. Material and Methods This institutional review board-approved retrospective study with waived informed consent included 180 pregnant women and was conducted at our medical center from March 2011 to April 2013. Biparietal diameter (BPD) and occipitofrontal diameter (OFD) results of fetal head US normograms were compared to normograms for MRI. We used Pearson and Spearman rho non-parametric correlation coefficients to assess the association between two quantitative variables, paired t-test for paired quantitative variables, and McNemar test for paired qualitative variables. Results The average BPD but not the average OFD percentiles in fetal head US differed significantly from the MRI results ( P < 0.0001). When looking at the accepted microcephaly threshold, both BPD and OFD percentiles differed significantly from MRI ( P < 0.0001 and P < 0.004, respectively). There was no correlation between US-measured skull biometry and MRI-measured brain biometry. Estimated cerebrospinal fluid volumes were significantly lower in the study group compared to 120 fetuses with normal findings in prenatal head US and MRI. Also, we have created a MRI-based normogram of fetal head circumference and gestational age. Conclusion The diagnosis of microcephaly by US alone may be insufficient and ideally should be validated by MRI before a final diagnosis is established.

  6. FluoSTIC: miniaturized fluorescence image-guided surgery system

    NASA Astrophysics Data System (ADS)

    Gioux, Sylvain; Coutard, Jean-Guillaume; Berger, Michel; Grateau, Henri; Josserand, Véronique; Keramidas, Michelle; Righini, Christian; Coll, Jean-Luc; Dinten, Jean-Marc

    2012-10-01

    Over the last few years, near-infrared (NIR) fluorescence imaging has witnessed rapid growth and is already used in clinical trials for various procedures. However, most clinically compatible imaging systems are optimized for large, open-surgery procedures. Such systems cannot be employed during head and neck oncologic surgeries because the system is not able to image inside deep cavities or allow the surgeon access to certain tumors due to the large footprint of the system. We describe a miniaturized, low-cost, NIR fluorescence system optimized for clinical use during oral oncologic surgeries. The system, termed FluoSTIC, employs a miniature, high-quality, consumer-grade lipstick camera for collecting fluorescence light and a novel custom circular optical fiber array for illumination that combines both white light and NIR excitation. FluoSTIC maintains fluorescence imaging quality similar to that of current large-size imaging systems and is 22 mm in diameter and 200 mm in height and weighs less than 200 g.

  7. Electro-Mechanical Simulation of a Large Aperture MOEMS Fabry-Perot Tunable Filter

    NASA Technical Reports Server (NTRS)

    Kuhn, Jonathan L.; Barclay, Richard B.; Greenhouse, Matthew A.; Mott, D. Brent; Satyapal, Shobita; Powers, Edward I. (Technical Monitor)

    2000-01-01

    We are developing a micro-machined electrostatically actuated Fabry-Perot tunable filter with a large clear aperture for application in high through-put wide-field imaging spectroscopy and lidar systems. In the first phase of this effort, we are developing key components based on coupled electro-mechanical simulations. In particular, the movable etalon plate design leverages high coating stresses to yield a flat surface in drum-head tension over a large diameter (12.5 mm). In this approach, the cylindrical silicon movable plate is back etched, resulting in an optically coated membrane that is suspended from a thick silicon support ring. Understanding the interaction between the support ring, suspended membrane, and coating is critical to developing surfaces that are flat to within stringent etalon requirements. In this work, we present the simulations used to develop the movable plate, spring suspension system, and electrostatic actuation mechanism. We also present results from tests of fabricated proof of concept components.

  8. Is the track of the Yellowstone hotspot driven by a deep mantle plume? - Review of volcanism, faulting, and uplift in light of new data

    USGS Publications Warehouse

    Pierce, K.L.; Morgan, L.A.

    2009-01-01

    Geophysical imaging of a tilted mantle plume extending at least 500??km beneath the Yellowstone caldera provides compelling support for a plume origin of the entire Yellowstone hotspot track back to its inception at 17??Ma with eruptions of flood basalts and rhyolite. The widespread volcanism, combined with a large volume of buoyant asthenosphere, supports a plume head as an initial phase. Estimates of the diameter of the plume head suggest it completely spanned the upper mantle and was fed from sources beneath the transition zone, We consider a mantle-plume depth to at least 1,000 km to best explain the large scale of features associated with the hotspot track. The Columbia River-Steens flood basalts form a northward-migrating succession consistent with the outward spreading of a plume head beneath the lithosphere. The northern part of the inferred plume head spread (pancaked) upward beneath Mesozoic oceanic crust to produce flood basalts, whereas basalt melt from the southern part intercepted and melted Paleozoic and older crust to produce rhyolite from 17 to 14??Ma. The plume head overlapped the craton margin as defined by strontium isotopes; westward motion of the North American plate has likely "scraped off" the head from the plume tail. Flood basalt chemistries are explained by delamination of the lithosphere where the plume head intersected this cratonic margin. Before reaching the lithosphere, the rising plume head apparently intercepted the east-dipping Juan de Fuca slab and was deflected ~ 250??km to the west; the plume head eventually broke through the slab, leaving an abruptly truncated slab. Westward deflection of the plume head can explain the anomalously rapid hotspot movement of 62??km/m.y. from 17 to 10??Ma, compared to the rate of ~ 25??km/m.y. from 10 to 2??Ma. A plume head-to-tail transition occurred in the 14-to-10-Ma interval in the central Snake River Plain and was characterized by frequent (every 200-300??ka for about 2??m.y. from 12.7 to 10.5??Ma) "large volume (> 7000??km3)", and high temperature rhyolitic eruptions (> 1000????C) along a ~ 200-km-wide east-west band. The broad transition area required a heat source of comparable area. Differing characteristics of the volcanic fields here may in part be due to variations in crustal composition but also may reflect development in differing parts of an evolving plume where the older fields may reflect the eruption from several volcanic centers located above very large and extensive rhyolitic magma chamber(s) over the detached plume head while the younger fields may signal the arrival of the plume tail intercepting and melting the lithosphere and generating a more focused rhyolitic magma chamber. The three youngest volcanic fields of the hotspot track started with large ignimbrite eruptions at 10.21, 6.62, and 2.05??Ma. They indicate hotspot migration N55?? E at ~ 25??km/m.y. compatible in direction and velocity with the North American Plate motion. The Yellowstone Crescent of High Terrain (YCHT) flares outward ahead of the volcanic progression in a pattern similar to a bow-wave, and thus favors a sub-lithospheric driver. Estimates of YCHT-uplift rates are between 0.1 and 0.4??mm/yr. Drainage divides have migrated northeastward with the hotspot. The Continental Divide and a radial drainage pattern now centers on the hotspot. The largest geoid anomaly in the conterminous U.S. is also centered on Yellowstone and, consistent with uplift above a mantle plume. Bands of late Cenozoic faulting extend south and west from Yellowstone. These bands are subdivided into belts based both on recency of offset and range-front height. Fault history within these belts suggests the following pattern: Belt I - starting activity but little accumulated offset; Belt II - peak activity with high total offset and activity younger than 14??ka; Belt III - waning activity with large offset and activity younger than 140??ka; and Belt IV - apparently dead on substanti

  9. Development of a Lightweight, High Strength, Collapsible Hose

    DTIC Science & Technology

    1989-02-01

    they will erupt through the elastomer as the hose exits the extrusion head and result in blistering of the cover and/or the lining. The jacket is...not successful. Extreme blistering of the elastomer occurred as the hose exited the extrusion head. The conclusion was drawn that moisture was not...HIGH STRENGTH, COLLAPSIBLE HOSE ABSTRACT This report documents an exploratory development effort to produce a 6-inch diameter, lightweight, high strength

  10. Normal radiological unossified hip joint space and femoral head size development during growth in 675 children and adolescents.

    PubMed

    Wegener, Veronika; Jorysz, Gabriele; Arnoldi, Andreas; Utzschneider, Sandra; Wegener, Bernd; Jansson, Volkmar; Heimkes, Bernhard

    2017-03-01

    Evaluation of hip joint space width during child growth is important to aid in the early diagnosis of hip pathology in children. We established reference values for hip joint space and femoral head size for each age. Hip joint space development during growth was retrospectively investigated medial and cranial in 1350 hip joints of children using standard anteroposterior supine plain pelvic radiographs. Maximum capital femoral epiphysis diameter and femoral radii were further more investigated. Hip joint space values show a slow decline during growth. Joint space was statistically significantly (p < 0.006) larger in boys than girls. Our hip joint space measurements on supine subjects seem slightly larger than those reported by Hughes on standing subjects. Evaluation of the femoral head diameter and the radii showed a size curve quite parallel to the known body growth charts. Radii medial and perpendicular to the physis are not statistically significantly different. We recommend to compare measurements of hip joint space at two locations to age dependent charts using the same imaging technique. During growth, a divergence in femoral head size from the expected values or loss of the spherical shape should raise the question of hip disorder. Clin. Anat. 30:267-275, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  11. A New Automated Way to Measure Polyethylene Wear in THA Using a High Resolution CT Scanner: Method and Analysis

    PubMed Central

    Maguire Jr., Gerald Q.; Noz, Marilyn E.; Olivecrona, Henrik; Zeleznik, Michael P.

    2014-01-01

    As the most advantageous total hip arthroplasty (THA) operation is the first, timely replacement of only the liner is socially and economically important because the utilization of THA is increasing as younger and more active patients are receiving implants and they are living longer. Automatic algorithms were developed to infer liner wear by estimating the separation between the acetabular cup and femoral component head given a computed tomography (CT) volume. Two series of CT volumes of a hip phantom were acquired with the femoral component head placed at 14 different positions relative to the acetabular cup. The mean and standard deviation (SD) of the diameter of the acetabular cup and femoral component head, in addition to the range of error in the expected wear values and the repeatability of all the measurements, were calculated. The algorithms resulted in a mean (±SD) for the diameter of the acetabular cup of 54.21 (±0.011) mm and for the femoral component head of 22.09 (±0.02) mm. The wear error was ±0.1 mm and the repeatability was 0.077 mm. This approach is applicable clinically as it utilizes readily available computed tomography imaging systems and requires only five minutes of human interaction. PMID:24587727

  12. 76 FR 9608 - Certain Welded Large Diameter Line Pipe From Mexico

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-18

    ... Large Diameter Line Pipe From Mexico AGENCY: United States International Trade Commission. ACTION... duty order on certain welded large diameter line pipe from Mexico. For further information concerning... welded large diameter line pipe from Mexico would not be likely to lead to continuation or recurrence of...

  13. Effect of carbon coating on spontaneous C12A7 whisker formation

    NASA Astrophysics Data System (ADS)

    Zaikovskii, Vladimir I.; Volodin, Alexander M.; Stoyanovskii, Vladimir O.; Cherepanova, Svetlana V.; Vedyagin, Aleksey A.

    2018-06-01

    A carbon nanoreactor concept was applied to study the stabilization effect of carbon shell on phase composition and morphology of dodecacalcium hepta-aluminate Ca12Al14O33. The starting C12A7 powder was obtained using aluminum and calcium hydroxides as precursors. Carbon shell was formed by a chemical vapor deposition of divinyl at 550 °C. After the calcination at 1400 °C, the product was characterized by X-ray diffraction analysis (XRD) and high resolution transmission electron microscopy (HRTEM). It was observed for a first time that spontaneous formation of calcium aluminate whiskers take place under the conditions described. Each whisker consists of a 'head' (globular particle of 0.5 microns in diameter) and a 'tail' (prolonged whisker of few microns in length and 0.1-0.2 microns in diameter). According to HRTEM, the 'head' is characterized with microcrystal lattice of Ca12Al14O33 compound. XRD data show the presence of CaAl2O4 phase traces. The 'head' and 'tail' of the whisker are covered with structured graphene layers of 10 nm and 3 nm, correspondingly.

  14. Double diameter boring tool

    DOEpatents

    Ashbaugh, F.A.; Murry, K.R.

    1986-02-10

    A boring tool and a method of operation are provided for boring two concentric holes of precision diameters and depths in a single operation. The boring tool includes an elongated tool body, a shank for attachment to a standard adjustable boring head which is used on a manual or numerical control milling machine and first and second diametrically opposed cutting flutes formed for cutting in opposite directions. The diameter of the elongated tool body is substantially equal to the distance from the first flute tip to the axis of rotation plus the distance from the second flute tip to the axis of rotation. The axis of rotation of the tool is spaced from the tool centerline a distance substantially equal to one-half the distance from the second flute tip to the axis of rotation minus one-half the distance from the first flute tip to the axis of rotation. The method includes the step of inserting the boring tool into the boring head, adjusting the distance between the tool centerline and the tool axis of rotation as described above and boring the two concentric holes.

  15. Double diameter boring tool

    DOEpatents

    Ashbaugh, Fred N.; Murry, Kenneth R.

    1988-12-27

    A boring tool and a method of operation are provided for boring two concentric holes of precision diameters and depths in a single operation. The boring tool includes an elongated tool body, a shank for attachment to a standard adjustable boring head which is used on a manual or numerical control milling machine and first and second diametrically opposed cutting edges formed for cutting in opposite directions. The diameter of the elongated tool body is substantially equal to the distance from the first cutting edge tip to the axis of rotation plus the distance from the second cutting edge tip to the axis of rotation. The axis of rotation of the tool is spaced from the tool centerline a distance substantially equal to one-half the distance from the second cutting edge tip to the axis of rotation minus one-half the distance from the first cutting edge tip to the axis of rotation. The method includes the step of inserting the boring tool into the boring head, adjusting the distance between the tool centerline and the tool axis of rotation as described above and boring the two concentric holes.

  16. Double diameter boring tool

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ashbaugh, F.A.; Murry, K.R.

    A boring tool and a method of operation are provided for boring two concentric holes of precision diameters and depths in a single operation. The boring tool includes an elongated tool body, a shank for attachment to a standard adjustable boring head which is used on a manual or numerical control milling machine and first and second diametrically opposed cutting flutes formed for cutting in opposite directions. The diameter of the elongated tool body is substantially equal to the distance from the first flute tip to the axis of rotation plus the distance from the second flute tip to themore » axis of rotation. The axis of rotation of the tool is spaced from the tool centerline a distance substantially equal to one-half the distance from the second flute tip to the axis of rotation minus one-half the distance from the first flute tip to the axis of rotation. The method includes the step of inserting the boring tool into the boring head, adjusting the distance between the tool centerline and the tool axis of rotation as described above and boring the two concentric holes.« less

  17. Extraction of high value added gelatin biopolymer from black tilapia (Oreochromis mossambicus) head bones

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sockalingam, K., E-mail: gd130106@siswa.uthm.edu.my; Abdullah, H. Z., E-mail: hasan@uthm.edu.my

    Black tilapia (Oreochromis mossambicus) fish head bones were evaluated for its possibilities in extracting gelatin. Head bones were subjected to pre-treatment with 3% of hydrochloric acid (HCl) for demineralization before undergoes thermal extraction process. The raw head bones were characterized via Scanning Electron Microscopy (SEM) in order to investigate the external and internal surface morphology. SEM images also reveal the presence of collagen fiber with 1 µm diameter in the head bone. The black tilapia fish head bones yields 5.75 % of gelatin in wet weight basis, indicating the possibility of this fish species as sources of gelatin. Further characterizations weremore » done on both raw head bones and extracted gelatin through Fourier Transform Infrared Spectroscopy (FTIR) and proximate analysis. The head bones gelatin shows high protein (10.55%) and ash (3.11 %) content with low moisture. This further proves the effectiveness of demineralization and extraction method used. The black tilapia fish head bones are found to be a prospective source of gelatin with good chemical and functional properties.« less

  18. Food waste composting: its use as a peat replacement.

    PubMed

    Farrell, M; Jones, D L

    2010-01-01

    We successfully co-composted catering waste with green waste and shredded paper to yield two high-nitrogen composts for use in horticulture. Sunflowers (Helianthus annuus L.) were grown in various mixtures of the compost and a commercially available peat-based compost to assess the efficacy of catering waste-based composts for peat replacement. Height, head diameter, seed mass and above-ground biomass were measured, with all mixtures giving a significant increase in yield or size over the commercially available peat-free control compost. We conclude that differences in physical structure governed sunflower growth over substrate chemistry, and none of the compost mixtures were nutrient deficient. We recommend that catering waste co-compost can be substituted to at least 75% within Sphagnum-based traditional growing media, providing a viable replacement for a large proportion of peat used as a growth medium in the horticulture industry. Our catering waste compost yielded similar seed head, seed mass and above-ground biomass values to 100% peat-based compost in all food waste compost blends tested in this study. 2010 Elsevier Ltd. All rights reserved.

  19. Performance of a Tracked Feller-Buncher with a Shear Head Operating in Small-Diameter Pine

    Treesearch

    J. Klepac

    2013-01-01

    A Tigercat 845D tracked feller-buncher equipped with a shear head was evaluated while performing a clearcut in a 15-year old Loblolly pine (Pinus taeda) plantation and a 18-year old natural stand. Mean density of the plantation was 573 TPA (Trees per Acre) while the natural stand averaged 328 TPA, with a slightly higher density of 390 TPA in the study area. Total cycle...

  20. Pulse tube cryocooler for IR applications

    NASA Astrophysics Data System (ADS)

    Korf, H.; Ruhlich, I.; Mai, M.; Thummes, G.

    2005-05-01

    Pulse tube cryocoolers (PTC) can be regarded as the next step in the development of the Stirling cooler. The major advantage vs. the Stirling cooler is the omission of any moving part in the cold head, resulting in significantly increased MTTF. Further advantages are higher mechanical robustness and stability and the potential for cost reduction. AIM developed PTC's for several years in close cooperation with the University of Giessen. As a recent result at AIM, Coaxial PTC cold head are available within the outline dimension of typical IR Stirling cold head of 13mm diameter. The achieved performance data are comparable to the serial data of the Stirling cold head. This PTC cold head is designed to be operated in the orifice mode without a double inlet which is known to cause instabilities. Technical details and performance data represent the current technical status at AIM.

  1. A novel device for head gesture measurement system in combination with eye-controlled human machine interface

    NASA Astrophysics Data System (ADS)

    Lin, Chern-Sheng; Ho, Chien-Wa; Chang, Kai-Chieh; Hung, San-Shan; Shei, Hung-Jung; Yeh, Mau-Shiun

    2006-06-01

    This study describes the design and combination of an eye-controlled and a head-controlled human-machine interface system. This system is a highly effective human-machine interface, detecting head movement by changing positions and numbers of light sources on the head. When the users utilize the head-mounted display to browse a computer screen, the system will catch the images of the user's eyes with CCD cameras, which can also measure the angle and position of the light sources. In the eye-tracking system, the program in the computer will locate each center point of the pupils in the images, and record the information on moving traces and pupil diameters. In the head gesture measurement system, the user wears a double-source eyeglass frame, so the system catches images of the user's head by using a CCD camera in front of the user. The computer program will locate the center point of the head, transferring it to the screen coordinates, and then the user can control the cursor by head motions. We combine the eye-controlled and head-controlled human-machine interface system for the virtual reality applications.

  2. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Weir, V; Zhang, J; Bruner, A

    Purpose: The AIRO Mobile CT system was recently introduced which overcomes the limitations from existing CT, CT fluoroscopy, and intraoperative O-arm. With an integrated table and a large diameter bore, the system is suitable for cranial, spine and trauma procedures, making it a highly versatile intraoperative imaging system. This study is to investigate radiation dose and image quality of the AIRO and compared with those from a routine CT scanner. Methods: Radiation dose was measured using a conventional 100mm pencil ionization chamber and CT polymethylmetacrylate (PMMA) body and head phantoms. Image quality was evaluated with a CATPHAN 500 phantom. Spatialmore » resolution, low contrast resolution (CNR), Modulation Transfer Function (MTF), and Normalized Noise Power Spectrum (NNPS) were analyzed. Results: Under identical technique conditions, radiation dose (mGy/mAs) from the AIRO mobile CT system (AIRO) is higher than that from a 64 slice CT scanner. MTFs show that both Soft and Standard filters of the AIRO system lost resolution quickly compared to the Sensation 64 slice CT. With the Standard kernel, the spatial resolutions of the AIRO system are 3lp/cm and 4lp/cm for the body and head FOVs, respectively. NNPSs show low frequency noise due to ring-like artifacts. Due to a higher dose in terms of mGy/mAs at both head and body FOV, CNR of the AIRO system is higher than that of the Siemens scanner. However detectability of the low contrast objects is poorer in the AIRO due to the presence of ring artifacts in the location of the targets. Conclusion: For image guided surgery applications, the AIRO has some advantages over a routine CT scanner due to its versatility, large bore size, and acceptable image quality. Our evaluation of the physical performance helps its future improvements.« less

  3. Morphometric analysis of acetabular dysplasia in cerebral palsy: three-dimensional CT study.

    PubMed

    Gose, Shinichi; Sakai, Takashi; Shibata, Toru; Murase, Tsuyoshi; Yoshikawa, Hideki; Sugamoto, Kazuomi

    2009-12-01

    Three-dimensional computed tomography (3D-CT) eliminates the positioning errors and allows the clinician to more accurately assess the radiographic parameters present. To elucidate the 3D geometry of the acetabulum and the extent of hip subluxation/dislocation in patients with cerebral palsy (CP), quantitative morphometric analysis was performed using 3D-CT data. We evaluated 150 hips in 75 patients with bilateral spastic CP. The mean age of the patients was 5.4 years (range: 2.7 to 6.9 y). The fitting plane of the ilium was projected onto the coronal plane and then onto the sagittal plane, and then the angle formed with a horizontal line was defined as CTalpha (the lateral opening angle) and CTbeta (the sagittal inclination angle), respectively. The center of the acetabulum and the femoral head were defined, and the distance between these centers was divided by the femoral head diameter, defined as CT migration percentage (CTMP, %). In 123 (82%) of the 150 hips, the femoral head center was located posteriorly, superiorly, and laterally relative to the acetabular center. Large CTalpha cases tended to show large CTMP. CTalpha and CTMP were significantly larger in the cases with Gross Motor Functional Classification System (GMFCS) level IV/V and spastic quadriplegia, than in the cases with GMFCS level II/III and spastic diplegia. CTbeta showed significant correlation with the acetabular defect on the lateral 3D reconstructed images. Three-dimensional acetabular geometry and migration percentage in CP patients can be analyzed quantitatively using 3D-CT regardless of the abnormal spastic posture. The extent of acetabular dysplasia and subluxation is more severe in patients with GMFCS level IV/V and spastic quadriplesia. Level 4.

  4. High-resolution brain SPECT imaging by combination of parallel and tilted detector heads.

    PubMed

    Suzuki, Atsuro; Takeuchi, Wataru; Ishitsu, Takafumi; Morimoto, Yuichi; Kobashi, Keiji; Ueno, Yuichiro

    2015-10-01

    To improve the spatial resolution of brain single-photon emission computed tomography (SPECT), we propose a new brain SPECT system in which the detector heads are tilted towards the rotation axis so that they are closer to the brain. In addition, parallel detector heads are used to obtain the complete projection data set. We evaluated this parallel and tilted detector head system (PT-SPECT) in simulations. In the simulation study, the tilt angle of the detector heads relative to the axis was 45°. The distance from the collimator surface of the parallel detector heads to the axis was 130 mm. The distance from the collimator surface of the tilted detector heads to the origin on the axis was 110 mm. A CdTe semiconductor panel with a 1.4 mm detector pitch and a parallel-hole collimator were employed in both types of detector head. A line source phantom, cold-rod brain-shaped phantom, and cerebral blood flow phantom were evaluated. The projection data were generated by forward-projection of the phantom images using physics models, and Poisson noise at clinical levels was applied to the projection data. The ordered-subsets expectation maximization algorithm with physics models was used. We also evaluated conventional SPECT using four parallel detector heads for the sake of comparison. The evaluation of the line source phantom showed that the transaxial FWHM in the central slice for conventional SPECT ranged from 6.1 to 8.5 mm, while that for PT-SPECT ranged from 5.3 to 6.9 mm. The cold-rod brain-shaped phantom image showed that conventional SPECT could visualize up to 8-mm-diameter rods. By contrast, PT-SPECT could visualize up to 6-mm-diameter rods in upper slices of a cerebrum. The cerebral blood flow phantom image showed that the PT-SPECT system provided higher resolution at the thalamus and caudate nucleus as well as at the longitudinal fissure of the cerebrum compared with conventional SPECT. PT-SPECT provides improved image resolution at not only upper but also at central slices of the cerebrum.

  5. A cost-effective method for femoral head allograft procurement for spinal arthrodesis: an alternative to commercially available allograft.

    PubMed

    Brown, Desmond A; Mallory, Grant W; Higgins, Dominique M; Abdulaziz, Mohammed; Huddleston, Paul M; Nassr, Ahmad; Fogelson, Jeremy L; Clarke, Michelle J

    2014-07-01

    A cost-effective procurement process for harvesting, storing, and using femoral head allografts is described. A brief review of the literature on the use of these allografts and a discussion of costs are provided. To describe a cost-effective method for the harvesting, storage, and use of femoral heads from patients undergoing total hip arthroplasty at our institution as a source of allograft bone. Spine fusion surgery uses a large proportion of commercially available bone grafts and bone substitutes. As the number of such surgical procedures performed in the United States continues to rise, these materials are at a historically high level of demand, which is projected to continue. Iliac crest bone autograft has historically been the standard of care, although this may be losing favor due to potential donor site morbidity. Although many substitutes are effective in promoting arthrodesis, their use is limited because of cost. Femoral heads are harvested under sterile conditions during total hip arthroplasty. The patient is tested per Food and Drug Administration regulations, and the tissue sample is cultured. The tissue is frozen and quarantined for a 6-month minimum pending repeat testing of donors and subsequently released for use. The relative cost-effectiveness of this tissue as a source of allograft bone is discussed. The average femoral head allograft is 54 to 56 mm in diameter and yields 50 cm of bone graft, with an average cost of US $435 for processing of the tissue resulting in a cost of US $8.70 per cm of allograft produced. Average production costs are significantly lower than those for other commonly available commercial bone grafts and substitutes. Femoral head allograft is a cost-effective alternative to commercially available allografts and bone substitutes. The method of procurement, storage, and use described could be adopted by other institutions in an effort to mitigate cost and increase supply. N/A.

  6. Small head circumference at birth and early age at adiposity rebound.

    PubMed

    Eriksson, J G; Kajantie, E; Lampl, M; Osmond, C; Barker, D J P

    2014-01-01

    The adiposity rebound is the age in childhood when body mass index is at a minimum before increasing again. The age at rebound is highly variable. An early age is associated with increased obesity in later childhood and adult life. We have reported that an early rebound is predicted by low weight gain between birth and 1 year of age and resulting low body mass index at 1 year. Here, we examine whether age at adiposity rebound is determined by influences during infancy or is a consequence of foetal growth. Our hypothesis was that measurements of body size at birth are related to age at adiposity rebound. Longitudinal study of 2877 children born in Helsinki, Finland, during 1934-1944. Early age at adiposity rebound was associated with small head circumference and biparietal diameter at birth, but not with other measurements of body size at birth. The mean age at adiposity rebound rose from 5.8 years in babies with a head circumference of ≤33 cm to 6.2 in babies with a head circumference of >36 cm (P for trend = 0.007). The association between thinness in infancy and early rebound became apparent at 6 months of age. It was not associated with adverse living conditions. In a simultaneous regression, small head circumference at birth, high mother's body mass index and tall maternal stature each had statistically significant trends with early adiposity rebound (P = 0.002, <0.001, 0.004). We hypothesize that the small head size at birth that preceded an early adiposity rebound was the result of inability to sustain a rapid intra-uterine growth trajectory initiated in association with large maternal body size. This was followed by catch-up growth in infancy, and we hypothesize that this depleted the infant's fat stores. © 2013 Scandinavian Physiological Society. Published by John Wiley & Sons Ltd.

  7. Sensitivity analysis of some critical factors affecting simulated intrusion volumes during a low pressure transient event in a full-scale water distribution system.

    PubMed

    Ebacher, G; Besner, M C; Clément, B; Prévost, M

    2012-09-01

    Intrusion events caused by transient low pressures may result in the contamination of a water distribution system (DS). This work aims at estimating the range of potential intrusion volumes that could result from a real downsurge event caused by a momentary pump shutdown. A model calibrated with transient low pressure recordings was used to simulate total intrusion volumes through leakage orifices and submerged air vacuum valves (AVVs). Four critical factors influencing intrusion volumes were varied: the external head of (untreated) water on leakage orifices, the external head of (untreated) water on submerged air vacuum valves, the leakage rate, and the diameter of AVVs' outlet orifice (represented by a multiplicative factor). Leakage orifices' head and AVVs' orifice head levels were assessed through fieldwork. Two sets of runs were generated as part of two statistically designed experiments. A first set of 81 runs was based on a complete factorial design in which each factor was varied over 3 levels. A second set of 40 runs was based on a latin hypercube design, better suited for experimental runs on a computer model. The simulations were conducted using commercially available transient analysis software. Responses, measured by total intrusion volumes, ranged from 10 to 366 L. A second degree polynomial was used to analyze the total intrusion volumes. Sensitivity analyses of both designs revealed that the relationship between the total intrusion volume and the four contributing factors is not monotonic, with the AVVs' orifice head being the most influential factor. When intrusion through both pathways occurs concurrently, interactions between the intrusion flows through leakage orifices and submerged AVVs influence intrusion volumes. When only intrusion through leakage orifices is considered, the total intrusion volume is more largely influenced by the leakage rate than by the leakage orifices' head. The latter mainly impacts the extent of the area affected by intrusion. Copyright © 2012 Elsevier Ltd. All rights reserved.

  8. Flexible rivet-set

    NASA Technical Reports Server (NTRS)

    Hespenhide, W. H.

    1969-01-01

    Tool sets rivets in tight places where the riveting head of the gun cannot be laid on the rivet. Tool may be made in any of many diameters and lengths, and its principle and use are not restricted to riveting.

  9. Circuit board routing attachment for Fermilab Gerber plotter

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lindenmeyer, C.

    1984-05-10

    A new and potentially important method of producing large circuit boards has been developed at Fermilab. A Gerber Flat Bed Plotter with an active area of 5' x 16' has been fitted with a machining head to produce a circuit board without the use of photography or chemicals. The modifications of the Gerber Plotter do not impair its use as a photoplotter or pen plotter, the machining head is merely exchanged with the standard attachments. The modifications to the program are minimal; this will be described in another report. The machining head is fitted with an air bearing motorized spindlemore » driven at a speed of 40,000 rpm to 90,000 rpm. The spindle also is provided with air bearings on its outside diameter, offering frictionless vertical travel guidance. Vertical travel of the spindle is driven by a spring return single acting air cylinder. An adjustable hydraulic damper slows the spindle travel near the end of its downward stroke. Two programmable stops control spindle down stroke position, and limit switches are provided for position feedback to the control system. A vacuum system collects chips at the cutter head. No lubrication or regular maintenance is required. The circuit board to be fabricated is supported on a porous plastic mat which allows table vacuum to hold the board in place while allowing the cutters or drills to cut through the board without damaging the rubber platen of the plotter. The perimeter of the board must be covered to the limits of the table vacuum area used to prevent excessive leakage.« less

  10. Large Femtosecond Two-Photon Absorption Cross-Sections of Fullerosome Vesicle Nanostructures Derived from Highly Photoresponsive Amphiphilic C60-Light-Harvesting Fluorene Dyad

    PubMed Central

    Wang, Min; Nalla, Venkatram; Jeon, Seaho; Mamidala, Venkatesh; Ji, Wei; Tan, Loon-Seng; Cooper, Thomas; Chiang, Long Y.

    2011-01-01

    We demonstrated ultrafast femtosecond nonlinear optical (NLO) absorption characteristics of bilayered fullerosome vesicle nanostructures derived from molecular self-assembly of amphiphilic oligo(ethylene glycolated) C60-(light-harvesting diphenylaminofluorene antenna). Fullerene conjugates were designed to enhance photoresponse in a femtosecond time scale by applying an isomerizable periconjugation linker between the C60 cage and diphenylaminofluorene antenna subunit in an intramolecular contact distance of only < 3.0 Å. Morphology of C60(>DPAF-EG12C1)-based fullerosome nanovesicles in H2O was characterized to consist of a bilayered shell with a sphere diameter of 20–70 nm and a chromophore shell-width of 9.0–10 nm, fitting well with a head-to-head packing configuration of the molecular length. At the estimated effective nanovesicle concentration as low as 5.5 × 10−8 MV (molecular molar concentration of 5.0 × 10−4 M) in H2O, two-photon absorption (2PA) phenomena were found to be the dominating photophysical events showing a large molar concentration-insensitive 2PA cross-section value equivalent to 8500 GM in a form of nanovesicles, on average. The observed NLO characteristics led to a sharp trend of efficient light-transmittance intensity reduction at the input laser intensity above 100 GW/cm2. PMID:22022620

  11. Hip resurfacing in patients under thirty years old: an attractive option for young and active patients.

    PubMed

    Krantz, Nicolas; Miletic, Bruno; Migaud, Henri; Girard, Julien

    2012-09-01

    Metal-on-metal hip resurfacing is offered as an alternative to traditional hip arthroplasty for young, active adults with advanced osteoarthritis. The concept of hip resurfacing is considered very attractive for this specific population (hard-on-hard bearing component with a large femoral head limiting the risk of dislocation, and allowing femoral bone stock preservation). A prospective clinical trial was designed to investigate the outcome of hip resurfacing in young patients (under 30 years old). We studied 24 hips in 22 patients. Mean age at operation was 24.9 years (range 17.1-29.9). No patient was lost to follow-up. There was no revision at average follow-up of 50.6 months (44-59). Mean UCLA activity score improved from 5.5 (1-9) pre-operatively to 7.6 (1-10) postoperatively (p < 0.001). Mean Harris hip score increased from 43.9 (19-67) to 89.3 (55-100) (p < 0.001). Radiological analysis discerned no osteolysis and no implant migration. The absence of short-term complications, such as mechanical failure or dislocation, is encouraging and leads us to think that mid-term results will be satisfactory. Moreover, the specific advantages of hip resurfacing (bone stock preservation, excellent stability, low risk of dislocation, large-diameter head) make the procedure a very attractive option for young subjects.

  12. Saturn Apollo Program

    NASA Image and Video Library

    1964-09-01

    This photograph shows the components for the Saturn V S-IC stage fuel tank assembly in the Manufacturing Engineering Laboratory, building 4707, at the Marshall Space Flight Center (MSFC). Left to right are upper head, lower head, and forward skirt assembly. Thirty-three feet in diameter, they will hold a total of 4,400,000 pounds of fuel. Although this tankage was assembled at MSFC, the elements were made by the Boeing Company at Wichita and the Michould Operations at New Orleans.

  13. The association of lymph node volume with cervical metastatic lesions in head and neck cancer patients.

    PubMed

    Liang, Ming-Tai; Chen, Clayton Chi-Chang; Wang, Ching-Ping; Wang, Chen-Chi; Lin, Whe-Dar; Liu, Shih-An

    2009-06-01

    The aim of this study was to determine if volume of cervical lymph node measured via computed tomography (CT) could differentiate metastatic from benign lesions in head and neck cancer patients. We conducted a retrospective review of chart and images in a tertiary referring center in Taiwan. Patients with head and neck cancers underwent radical, modified radical or functional neck dissection were enrolled. The CT images before operation were reassessed by a radiologist and were compared with the results of pathological examination. A total of 102 patients were included for final analyses. Most patients were male (n = 96, 94%) and average age was 50.1 years. Although the average nodal volume in patients with cervical metastases was higher than those of patients without cervical metastases, it was not an independent factor associated with cervical metastasis after controlling for other variables; however, central nodal necrosis on enhanced CT image [odds ratio (OR) 18.95, P = 0.008) and minimal axial diameter >7.5 mm (OR 6.868, P = 0.001) were independent factors correlated with cervical metastasis. Therefore, the volume of cervical lymph node measured from CT images cannot predict cervical metastases in head and neck cancer patients. Measurement of minimal axial diameter of the largest lymph node is a simple and more accurate way to predict cervical metastasis instead.

  14. Reference range of fetal transverse cerebellar diameter between 18 and 24 weeks of pregnancy in a Brazilian population.

    PubMed

    Araujo Júnior, Edward; Martins, Wellington P; Nardozza, Luciano Marcondes Machado; Pires, Claudio Rodrigues; Filho, Sebastião Marques Zanforlin

    2015-02-01

    To determine a reference range of fetal transverse cerebellar diameter in Brazilian population. This was a retrospective cross-sectional study with 3772 normal singleton pregnancies between 18 and 24 weeks of pregnancy. The transverse cerebellar diameter was measured on the axial plane of the fetal head at the level of the lateral ventricles, including the thalamus, cavum septum pellucidum, and third ventricle. To assess the correlation between transverse cerebellar diameter and gestational age, polynomial equations were calculated, with adjustments by the determination coefficient (R2). The mean of fetal transverse cerebellar diameter ranged from 18.49 ± 1.24 mm at 18 weeks to 25.86 ± 1.66 mm at 24 weeks of pregnancy. We observed a good correlation between transverse cerebellar diameter and gestational age, which was best represented by a linear equation: transverse cerebellar diameter: -6.21 + 1.307*gestational age (R2 = 0.707). We determined a reference range of fetal transverse cerebellar diameter for the second trimester of pregnancy in Brazilian population. © The Author(s) 2014.

  15. On-machine precision preparation and dressing of ball-headed diamond wheel for the grinding of fused silica

    NASA Astrophysics Data System (ADS)

    Chen, Mingjun; Li, Ziang; Yu, Bo; Peng, Hui; Fang, Zhen

    2013-09-01

    In the grinding of high quality fused silica parts with complex surface or structure using ball-headed metal bonded diamond wheel with small diameter, the existing dressing methods are not suitable to dress the ball-headed diamond wheel precisely due to that they are either on-line in process dressing which may causes collision problem or without consideration for the effects of the tool setting error and electrode wear. An on-machine precision preparation and dressing method is proposed for ball-headed diamond wheel based on electrical discharge machining. By using this method the cylindrical diamond wheel with small diameter is manufactured to hemispherical-headed form. The obtained ball-headed diamond wheel is dressed after several grinding passes to recover geometrical accuracy and sharpness which is lost due to the wheel wear. A tool setting method based on high precision optical system is presented to reduce the wheel center setting error and dimension error. The effect of electrode tool wear is investigated by electrical dressing experiments, and the electrode tool wear compensation model is established based on the experimental results which show that the value of wear ratio coefficient K' tends to be constant with the increasing of the feed length of electrode and the mean value of K' is 0.156. Grinding experiments of fused silica are carried out on a test bench to evaluate the performance of the preparation and dressing method. The experimental results show that the surface roughness of the finished workpiece is 0.03 μm. The effect of the grinding parameter and dressing frequency on the surface roughness is investigated based on the measurement results of the surface roughness. This research provides an on-machine preparation and dressing method for ball-headed metal bonded diamond wheel used in the grinding of fused silica, which provides a solution to the tool setting method and the effect of electrode tool wear.

  16. Humeral development from neonatal period to skeletal maturity--application in age and sex assessment.

    PubMed

    Rissech, Carme; López-Costas, Olalla; Turbón, Daniel

    2013-01-01

    The goal of the present study is to examine cross-sectional information on the growth of the humerus based on the analysis of four measurements, namely, diaphyseal length, transversal diameter of the proximal (metaphyseal) end of the shaft, epicondylar breadth and vertical diameter of the head. This analysis was performed in 181 individuals (90 ♂ and 91 ♀) ranging from birth to 25 years of age and belonging to three documented Western European skeletal collections (Coimbra, Lisbon and St. Bride). After testing the homogeneity of the sample, the existence of sexual differences (Student's t- and Mann-Whitney U-test) and the growth of the variables (polynomial regression) were evaluated. The results showed the presence of sexual differences in epicondylar breadth above 20 years of age and vertical diameter of the head from 15 years of age, thus indicating that these two variables may be of use in determining sex from that age onward. The growth pattern of the variables showed a continuous increase and followed first- and second-degree polynomials. However, growth of the transversal diameter of the proximal end of the shaft followed a fourth-degree polynomial. Strong correlation coefficients were identified between humeral size and age for each of the four metric variables. These results indicate that any of the humeral measurements studied herein is likely to serve as a useful means of estimating sub-adult age in forensic samples.

  17. Finite Element Stress Analysis of Spent Nuclear Fuel Disposal Canister in a Deep Geological Repository

    NASA Astrophysics Data System (ADS)

    Kwon, Young Joo; Choi, Jong Won

    This paper presents the finite element stress analysis of a spent nuclear fuel disposal canister to provide basic information for dimensioning the canister and configuration of canister components and consequently to suggest the structural analysis methodology for the disposal canister in a deep geological repository which is nowadays very important in the environmental waste treatment technology. Because of big differences in the pressurized water reactor (PWR) and the Canadian deuterium and uranium reactor (CANDU) fuel properties, two types of canisters are conceived. For manufacturing, operational reasons and standardization, however, both canisters have the same outer diameter and length. The construction type of canisters introduced here is a solid structure with a cast insert and a corrosion resistant overpack. The structural stress analysis is carried out using a finite element analysis code, NISA, and focused on the structural strength of the canister against the expected external pressures due to the swelling of the bentonite buffer and the hydrostatic head. The canister must withstand these large pressure loads. Consequently, canisters presented here contain 4 PWR fuel assemblies and 33×9 CANDU fuel bundles. The outside diameter of the canister for both fuels is 122cm and the cast insert diameter is 112cm. The total length of the canister is 483cm with the lid/bottom and the outer shell of 5cm.

  18. Diagnostic accuracy of referral criteria for head circumference to detect hydrocephalus in the first year of life.

    PubMed

    van Dommelen, Paula; Deurloo, Jacqueline A; Gooskens, Rob H; Verkerk, Paul H

    2015-04-01

    Increased head circumference is often the first and main sign leading to the diagnosis of hydrocephalus. Our aim is to investigate the diagnostic accuracy of referral criteria for head circumference to detect hydrocephalus in the first year of life. A reference group with longitudinal head circumference data (n = 1938) was obtained from the Social Medical Survey of Children Attending Child Health Clinics study. The case group comprised infants with hydrocephalus treated in a tertiary pediatric hospital who had not already been detected during pregnancy (n = 125). Head circumference data were available for 43 patients. Head circumference data were standardized according to gestational age-specific references. Sensitivity and specificity of a very large head circumference (>2.5 standard deviations on the growth chart) were, respectively, 72.1% (95% confidence interval [CI]: 56.3-84.7) and 97.1% (95% CI:96.2-97.8). These figures were, respectively, 74.4% (95% CI: 58.8-86.5) and 93.0% (95% CI:91.8-94.1) for a large head circumference (>2.0 standard deviation), and 76.7% (95% CI:61.4-88.2) and 96.5% (95% CI:95.6-97.3) for a very large head circumference and/or a very large (>2.5 standard deviation) progressive growth of head circumference. A very large head circumference and/or a very large progressive growth of head circumference shows the best diagnostic accuracy to detect hydrocephalus at an early stage. Gestational age-specific growth charts are recommended. Further improvements may be possible by taking into account parental head circumference. Copyright © 2015 Elsevier Inc. All rights reserved.

  19. Ecological Importance of Large-Diameter Trees in a Temperate Mixed-Conifer Forest

    PubMed Central

    Lutz, James A.; Larson, Andrew J.; Swanson, Mark E.; Freund, James A.

    2012-01-01

    Large-diameter trees dominate the structure, dynamics and function of many temperate and tropical forests. Although both scaling theory and competition theory make predictions about the relative composition and spatial patterns of large-diameter trees compared to smaller diameter trees, these predictions are rarely tested. We established a 25.6 ha permanent plot within which we tagged and mapped all trees ≥1 cm dbh, all snags ≥10 cm dbh, and all shrub patches ≥2 m2. We sampled downed woody debris, litter, and duff with line intercept transects. Aboveground live biomass of the 23 woody species was 507.9 Mg/ha, of which 503.8 Mg/ha was trees (SD = 114.3 Mg/ha) and 4.1 Mg/ha was shrubs. Aboveground live and dead biomass was 652.0 Mg/ha. Large-diameter trees comprised 1.4% of individuals but 49.4% of biomass, with biomass dominated by Abies concolor and Pinus lambertiana (93.0% of tree biomass). The large-diameter component dominated the biomass of snags (59.5%) and contributed significantly to that of woody debris (36.6%). Traditional scaling theory was not a good model for either the relationship between tree radii and tree abundance or tree biomass. Spatial patterning of large-diameter trees of the three most abundant species differed from that of small-diameter conspecifics. For A. concolor and P. lambertiana, as well as all trees pooled, large-diameter and small-diameter trees were spatially segregated through inter-tree distances <10 m. Competition alone was insufficient to explain the spatial patterns of large-diameter trees and spatial relationships between large-diameter and small-diameter trees. Long-term observations may reveal regulation of forest biomass and spatial structure by fire, wind, pathogens, and insects in Sierra Nevada mixed-conifer forests. Sustaining ecosystem functions such as carbon storage or provision of specialist species habitat will likely require different management strategies when the functions are performed primarily by a few large trees as opposed to many smaller trees. PMID:22567132

  20. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rigali, Mark J.; Pye, Steven; Hardin, Ernest

    This study considers the feasibility of large diameter deep boreholes for waste disposal. The conceptual approach considers examples of deep large diameter boreholes that have been successfully drilled, and also other deep borehole designs proposed in the literature. The objective for large diameter boreholes would be disposal of waste packages with diameters of 22 to 29 inches, which could enable disposal of waste forms such as existing vitrified high level waste. A large-diameter deep borehole design option would also be amenable to other waste forms including calcine waste, treated Na-bonded and Na-bearing waste, and Cs and Sr capsules.

  1. Differentiation of benign from malignant cervical lymph nodes in patients with head and neck cancer using PET/CT imaging.

    PubMed

    Payabvash, Seyedmehdi; Meric, Kaan; Cayci, Zuzan

    2016-01-01

    To differentiate malignant from benign cervical lymph nodes in patients with head/neck cancer. In this retrospective study, 39 patients with primary head/neck cancer who underwent Positron Emission Tomography (PET)/Computerized Tomography (CT) and image-guided lymph node biopsy were included. Overall, 23 (59%) patients had biopsy-proven malignant cervical lymphadenopathy. Malignant lymph nodes had higher maximum standardized uptake (SUV-max) value (P<.001) and short-axis diameter (P=.015) compared to benign nodes. An SUV-max of ≥2.5 was 100% sensitive, and an SUV-max ≥5.5 was 100% specific for malignant lymphadenopathy. The PET/CT SUV-max value can help with differentiation of malignant cervical lymph nodes in patients with head/neck cancer. Published by Elsevier Inc.

  2. "Tripolar" hip arthroplasty for failed hip resurfacing: nineteen years follow-up.

    PubMed

    Scheerlinck, T; Casteleyn, P P

    2001-10-01

    The authors describe the case of a 37-year-old patient who sustained a subcapital femoral neck fracture six months after ICLH double-cup hip resurfacing. As the polyethylene acetabular resurfacing component was undamaged and well fixed, a standard femoral stem with a bipolar head was inserted. The outer diameter of the bipolar head was chosen to fit the resurfacing socket. The "tripolar" hip arthroplasty has functioned well for 19 years and was revised for aseptic cup loosening. The cemented femoral stem was still well fixed and was not revised. Although the "tripolar" hip has functioned well in our case, we believe it is not indicated for metal on metal bearings. In this case the use of an appropriate modular head with a correct head-socket clearance is preferred.

  3. Ivermectin lipid-based nanocarriers as novel formulations against head lice.

    PubMed

    Ullio-Gamboa, Gabriela; Palma, Santiago; Benoit, Jean Pierre; Allemandi, Daniel; Picollo, María Inés; Toloza, Ariel Ceferino

    2017-08-01

    The use of pyrethroids to control the human head louse, Pediculus humanus capitis De Geer (Anoplura: Pediculidae), has suffered considerable loss of efficacy due to the evolution of resistance. Thus, the development of efficiently insecticide delivery systems is imperative for the control of head lice. We studied the insecticidal activity of ivermectin-loaded lipid nanocapsules (IVM-LNC) against permethrin-resistant head lice from Argentina. The LNC, prepared by a phase inversion procedure, were characterized in terms of size, surface potential, and physical stability. These nanoparticles were nearly spherical with mean diameters of 55 nm and narrow size distribution (PI ≤ 0.2). The KT 50 mortality values of head lice after exposure to two IVM-LNC formulations (0.11 and 0.28%) were significantly smaller (5 and 3 h, respectively) compared to those exposed only to LNC control group (8 h). This investigation showed the effectiveness in the encapsulation of ivermectin (IVM) into stable LNC dispersion with a potential clinical activity against head lice.

  4. Automatic soldering machine

    NASA Technical Reports Server (NTRS)

    Stein, J. A.

    1974-01-01

    Fully-automatic tube-joint soldering machine can be used to make leakproof joints in aluminum tubes of 3/16 to 2 in. in diameter. Machine consists of temperature-control unit, heater transformer and heater head, vibrator, and associated circuitry controls, and indicators.

  5. Alterations in Skeletal Muscle Microcirculation of Head-Down Tilted Rats

    NASA Technical Reports Server (NTRS)

    Musacchia, X. J.; Stepke, Bernhard; Fleming, John T.; Joshua, Irving G.

    1992-01-01

    In this study we assessed the function of microscopic blood vessels in skeletal muscle (cremaster muscle) for alterations which may contribute to the observed elevation of blood pressure associated with head-down tilted whole body suspension (HDT/WBS), a model of weightlessness. Arteriolar baseline diameters, vasoconstrictor responses to norepinephrine (NE) and vasodilation to nitroprusside (NP) were assessed in control rats, rats suspended for 7 or 14 day HDT/WBS rats, and rats allowed to recover for 1 day after 7 days HDT/WBS. Neither baseline diameters nor ability to dilate were influenced by HDT/WBS. Maximum vasoconstriction to norepinephrine was significantly greater in arterioles of hypertensive 14 day HDT/WBS rats. This first study of the intact microvasculature in skeletal muscle indicates that an elevated contractility of arterioles to norepinephrine in suspended rats, and suggests an elevated peripheral resistance in striated muscle may contribute to the increase in blood pressures among animals subjected to HDT/WBS.

  6. Minimizing water consumption when producing hydropower

    NASA Astrophysics Data System (ADS)

    Leon, A. S.

    2015-12-01

    In 2007, hydropower accounted for only 16% of the world electricity production, with other renewable sources totaling 3%. Thus, it is not surprising that when alternatives are evaluated for new energy developments, there is strong impulse for fossil fuel or nuclear energy as opposed to renewable sources. However, as hydropower schemes are often part of a multipurpose water resources development project, they can often help to finance other components of the project. In addition, hydropower systems and their associated dams and reservoirs provide human well-being benefits, such as flood control and irrigation, and societal benefits such as increased recreational activities and improved navigation. Furthermore, hydropower due to its associated reservoir storage, can provide flexibility and reliability for energy production in integrated energy systems. The storage capability of hydropower systems act as a regulating mechanism by which other intermittent and variable renewable energy sources (wind, wave, solar) can play a larger role in providing electricity of commercial quality. Minimizing water consumption for producing hydropower is critical given that overuse of water for energy production may result in a shortage of water for other purposes such as irrigation, navigation or fish passage. This paper presents a dimensional analysis for finding optimal flow discharge and optimal penstock diameter when designing impulse and reaction water turbines for hydropower systems. The objective of this analysis is to provide general insights for minimizing water consumption when producing hydropower. This analysis is based on the geometric and hydraulic characteristics of the penstock, the total hydraulic head and the desired power production. As part of this analysis, various dimensionless relationships between power production, flow discharge and head losses were derived. These relationships were used to withdraw general insights on determining optimal flow discharge and optimal penstock diameter. For instance, it was found that for minimizing water consumption, the ratio of head loss to gross head should not exceed about 15%. Two examples of application are presented to illustrate the procedure for determining optimal flow discharge and optimal penstock diameter for impulse and reaction turbines.

  7. 77 FR 30260 - Welded Large Diameter Line Pipe From Japan: Notice of Rescission of Antidumping Duty...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-22

    ... Administration [A-588-857] Welded Large Diameter Line Pipe From Japan: Notice of Rescission of Antidumping Duty... Japan. The review covers five producers/exporters of welded large diameter line pipe from Japan, which... diameter line pipe from Japan for the period December 1, 2010, through November 30, 2011. See Antidumping...

  8. [Material found on the cleaned diamond turbine drilling heads after injury cases].

    PubMed

    Dielert, E

    1979-06-01

    Grinding of the hard tissues of the teeth with diamond points and airotor led to bullet-like flying off of part of the instrument. The causes were investigated: Unsatisfactory fixation in the turbine head, deficient material in the rotating instrument, unnecessary notches in the shaft resulting in reduction of diameter, and finally the so far uncorrected radial vibration of the rotating instrument. All of these causes may result in plastic deformation or breakage of the points.

  9. Proximal femoral anatomy and collared stems in hip arthroplasty: is a single collar size sufficient?

    PubMed

    Bonin, Nicolas; Gedouin, Jean-Emmanuel; Pibarot, Vincent; Bejui-Hughues, Jacques; Bothorel, Hugo; Saffarini, Mo; Batailler, Cécile

    2017-10-03

    Even if the benefits of collars are unclear, they remain widely used, in several femoral stem designs. This study aimed to determine whether collar size should be proportional to hip dimensions and morphology. The hypothesis was that the collar should be larger for greater stem sizes and for varus femoral necks. Computed Tomography scans of 204 healthy hips were digitally analysed and manually templated to determine principle dimensions, appropriate stem size and model, as well as cortical distance at the femoral calcar (ideal collar size). Univariable analysis revealed that cortical distance was moderately correlated with mediolateral offset (r = 0.572; p < 0.0001) and stem model (r = 0.520; p < 0.0001). Cortical distance was weakly correlated with head diameter (r = 0.399; p < 0.0001), stem size (r = 0.200; p = 0.017), and patient gender (r = 0.361; p < 0.0001). Multivariable analysis confirmed that stem model (p < 0.0001) and head diameter (p = 0.0162) are directly correlated to cortical distance. We found that cortical distance along the femoral calcar is directly correlated with the model of the stem implanted ('standard' or 'varus') and with the head diameter. This cortical distance indicates optimal collar size, which would grant maximum calcar coverage without prosthetic overhang. Collar size should be proportional to the size of the operated hip, and should be larger for 'varus' stem models than for 'standard' stem models.

  10. Reducing the rate of early primary hip dislocation by combining a change in surgical technique and an increase in femoral head diameter to 36 mm.

    PubMed

    Ho, Ki Wai Kevin; Whitwell, George S; Young, Steve K

    2012-07-01

    We report how changes to our total hip arthroplasty (THA) surgical practise lead to a decrease in early hip dislocation rates. Group B consisted of 421 consecutive primary THA operations performed via a posterior approach. The operative technique included a meticulous repair of the posterior capsule, alignment of the acetabular cup with the transverse acetabular ligament (TAL) and a 36-mm-diameter femoral head. We compared the dislocation rates and cost implications of this technique to a historical control Group A consisting of 389 patients. The control group had their THA performed with no repair of the capsule, no identification of the TAL and all received a 28-mm-diameter head. Our primary outcome is the rate of early hip dislocation and we hypothesised that we can reduce the rate of early hip dislocation with this new regime. In Group B there were no early dislocations (within 6 months) and two (0.5 %) dislocations within 18 months; minimum follow-up time was 18 months with a range of (18-96 months). This compared to a 1.8 % early dislocation rate and a 2.6 % rate at 18 months in Group A; minimum follow-up time was 60 months with a range of (60-112 months). These results were statistically significant (p = 0.006). We suggest that when primary hip arthroplasty is performed through a posterior approach, a low early dislocation rate can be achieved using the described methods.

  11. Widefield TSCSPC-systems with large-area-detectors: application in simultaneous multi-channel-FLIM

    NASA Astrophysics Data System (ADS)

    Stepanov, Sergei; Bakhlanov, Sergei; Drobchenko, Evgeny; Eckert, Hann-Jörg; Kemnitz, Klaus

    2010-11-01

    Novel proximity-type Time- and Space-Correlated Single Photon Counting (TSCSPC) crossed-delay-line (DL)- and multi-anode (MA)-systems of outstanding performance and homogeneity were developed, using large-area detector heads of 25 and 40 mm diameter. Instrument response functions IRF(space) = (60 +/- 5) μm FWHM and IRF(time) = (28 +/- 3) ps FWHM were achieved over the full 12 cm2 area of the detector. Deadtime at throughput of 105 cps is 10% for "high-resolution" system and 5% in the "video"-system at 106 cps, at slightly reduced time- and space resolution. A fluorescence lifetime of (3.5 +/- 1) ps can be recovered from multi-exponential dynamics of a single living cyanobacterium (Acaryochloris marina). The present large-area detectors are particularly useful in simultaneous multichannel applications, such as 2-colour anisotropy or 4-colour lifetime imaging, utilizing dual- or quad-view image splitters. The long-term stability, low- excitation-intensity (< 100 mW/cm2) widefield systems enable minimal-invasive observation, without significant bleaching or photodynamic reactions, thus allowing long-period observation of up to several hours in living cells.

  12. Ultrasonic scanning system for in-place inspection of brazed-tube joints

    NASA Technical Reports Server (NTRS)

    Haralson, H. S.; Haynes, J. L.; Wages, C. G.

    1971-01-01

    System detects defects of .051 cm in diameter and larger. System incorporates scanning head assembly including boot enclosed transducer, slip ring assembly, drive mechanism, and servotransmitter. Ultrasonic flaw detector, prototype recorder, and special recorder complete system.

  13. [Effectiveness of multiple small-diameter drilling decompression combined with hip arthroscopy for early osteonecrosis of the femoral head].

    PubMed

    Li, Ji; Li, Zhongli; Su, Xiangzheng; Liu, Chunhui; Zhang, Hao; Wang, Ketao

    2017-09-01

    To evaluate the effectiveness of multiple small-diameter drilling decompression combined with hip arthroscopy for early oeteonecrosis of the femoral head (ONFH). Between March 2010 and December 2013, 91 patients with early ONFH were treated with the operation of multiple small-diameter drilling decompression combined with hip arthroscopy in 39 cases (53 hips, group A) or with drilling decompression alone in 52 cases (74 hips, group B). The patients in 2 groups had obvious hip pain and limited motion before operation. There was no significant difference in gender, age, etiology, effected side, stage of osteonecrosis, and preoperative Harris score between 2 groups ( P >0.05). All operations succeeded and all incisions healed by first intention. The operation time was significantly longer in group A [(73.3±10.6) minutes] than in group B [(41.5±7.2) minutes] ( t =8.726, P =0.000). Temporary of sciatic nerve apraxia after operation occurred in 2 patients of group A, and no complication occurred in other patients. Patients were followed up 24-52 months (mean, 39.3 months) in group A and 24-48 months (mean, 34.6 months) in group B. At last follow-up, the Harris scores were 83.34±8.76 in group A and 76.61±9.22 in group B, showing significant differences when compared between 2 groups ( t =-4.247, P =0.029) and when compared with preoperative values in 2 groups ( t =-10.327, P =0.001; t =-8.216, P =0.008). X-ray films showed that the collapse of the femoral head was observed in 6 hips (1 hip at stage Ⅰand 5 hips at stage Ⅱ) in group A, and in 16 hips (4 hips at stageⅠand 12 hips at stage Ⅱ) in group B; and hip arthroplasty was performed. The total effective rates were 88.68% (47/53) in group A and 78.38% (58/74) in group B, respectively; showing significant difference between 2 groups ( χ 2 =5.241, P =0.041). Multiple small-diameter drilling decompression combined with hip arthroscopy is effective in pain relief, improvement of hip function, slowing-down the process of femoral head necrosis, delaying the need for total hip arthroplasty in patients with early ONFH.

  14. Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation

    PubMed Central

    Schneider, Craig S.; Xu, Qingguo; Boylan, Nicholas J.; Chisholm, Jane; Tang, Benjamin C.; Schuster, Benjamin S.; Henning, Andreas; Ensign, Laura M.; Lee, Ethan; Adstamongkonkul, Pichet; Simons, Brian W.; Wang, Sho-Yu S.; Gong, Xiaoqun; Yu, Tao; Boyle, Michael P.; Suk, Jung Soo; Hanes, Justin

    2017-01-01

    Mucoadhesive particles (MAP) have been widely explored for pulmonary drug delivery because of their perceived benefits in improving particle residence in the lungs. However, retention of particles adhesively trapped in airway mucus may be limited by physiologic mucus clearance mechanisms. In contrast, particles that avoid mucoadhesion and have diameters smaller than mucus mesh spacings rapidly penetrate mucus layers [mucus-penetrating particles (MPP)], which we hypothesized would provide prolonged lung retention compared to MAP. We compared in vivo behaviors of variously sized, polystyrene-based MAP and MPP in the lungs following inhalation. MAP, regardless of particle size, were aggregated and poorly distributed throughout the airways, leading to rapid clearance from the lungs. Conversely, MPP as large as 300 nm exhibited uniform distribution and markedly enhanced retention compared to size-matched MAP. On the basis of these findings, we formulated biodegradable MPP (b-MPP) with an average diameter of <300 nm and examined their behavior following inhalation relative to similarly sized biodegradable MAP (b-MAP). Although b-MPP diffused rapidly through human airway mucus ex vivo, b-MAP did not. Rapid b-MPP movements in mucus ex vivo correlated to a more uniform distribution within the airways and enhanced lung retention time as compared to b-MAP. Furthermore, inhalation of b-MPP loaded with dexamethasone sodium phosphate (DP) significantly reduced inflammation in a mouse model of acute lung inflammation compared to both carrier-free DP and DP-loaded MAP. These studies provide a careful head-to-head comparison of MAP versus MPP following inhalation and challenge a long-standing dogma that favored the use of MAP for pulmonary drug delivery. PMID:28435870

  15. 78 FR 12784 - Welded Large Diameter Line Pipe From Japan; Scheduling of a Full Five-Year Review Concerning the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-25

    ... Diameter Line Pipe From Japan; Scheduling of a Full Five-Year Review Concerning the Antidumping Duty Order on Welded Large Diameter Line Pipe From Japan AGENCY: United States International Trade Commission... revocation of the antidumping duty order on welded large diameter line pipe from Japan would be likely to...

  16. Total Hip Arthroplasty Using a Polished Tapered Cemented Stem in Hereditary Multiple Exostosis

    PubMed Central

    Kanda, Akio; Kaneko, Kazuo; Obayashi, Osamu; Mogami, Atsuhiko

    2016-01-01

    A 61-year-old Japanese man underwent right total hip arthroplasty for hereditary multiple exostosis. At first presentation, he had suffered from coxalgia for a long time. On radiographic images, there was a gigantic femoral head, increased shaft angle, and large diameter of the femoral neck. He had also developed coxarthrosis and severe pain of the hip joint. The transformation of the proximal femur bone causes difficulty in setting a cementless total hip prosthesis. Therefore, total hip arthroplasty using a cemented polished tapered stem was performed via a direct lateral approach. Using a cemented polished tapered stem allowed us to deal with the femoral bone transformation and bone substance defectiveness due to exostosis and also minimized the invasiveness of the operation. PMID:27127668

  17. [Pancreaticojejunal anastomosis. Indication, technique and results].

    PubMed

    Gebhardt, C

    2001-01-01

    Pancreaticojejunal anastomosis. Indication, technique and results. Pancreaticojejunal anastomoses are performed for the treatment of chronic pancreatitis and after resection of pancreatic carcinomas. In chronic pancreatitis by drainage procedures (Partington-Rochelle and Puestow-Gillesby) one can expect good long term results, if the diameter of the pancreatic duct is at least 1 cm and the length of the anastomosis 6 cm. The duodenumpreserving head resection (Beger or Frey) is a combination of resection and drainage and is significant in the therapy of inflammatory head processes. In the surgical treatment of pancreatic carcinomas pancreaticojejunostomies are applied after head resection (Whipple-, pyloruspreserving modification). The end-to-side mucosa-mucosa anastomosis offers the best results concerning postoperativ complications and mortality rates.

  18. Ultrasonic probe system for the bore-side inspection of tubes and welds therein

    DOEpatents

    Cook, K. Von; Koerner, Dan W.; Cunningham, Jr., Robert A.; Murrin, Jr., Horace T.

    1977-07-26

    A probe system is provided for the bore-side inspection of tube-to-header welds and the like for small diameter tubes. The probe head of the system includes an ultrasonic transmitter-receiver transducer, a separate ultrasonic receiver, a reflector associated with the transducer to properly orient the ultrasonic signal with respect to a tube wall, a baffle to isolate the receiver from the transducer, and means for maintaining the probe head against the tube wall under investigation. Since the probe head must rotate to inspect along a helical path, special ultrasonic signal connections are employed. Through the use of the probe, flaws at either the inner or outer surfaces may be detected.

  19. On the extraordinary strength of Prince Rupert's drops

    NASA Astrophysics Data System (ADS)

    Aben, H.; Anton, J.; Öis, M.; Viswanathan, K.; Chandrasekar, S.; Chaudhri, M. M.

    2016-12-01

    Prince Rupert's drops (PRDs), also known as Batavian tears, have been in existence since the early 17th century. They are made of a silicate glass of a high thermal expansion coefficient and have the shape of a tadpole. Typically, the diameter of the head of a PRD is in the range of 5-15 mm and that of the tail is 0.5 to 3.0 mm. PRDs have exceptional strength properties: the head of a PRD can withstand impact with a small hammer, or compression between tungsten carbide platens to high loads of ˜15 000 N, but the tail can be broken with just finger pressure leading to catastrophic disintegration of the PRD. We show here that the high strength of a PRD comes from large surface compressive stresses in the range of 400-700 MPa, determined using techniques of integrated photoelasticity. The surface compressive stresses can suppress Hertzian cone cracking during impact with a small hammer or compression between platens. Finally, it is argued that when the compressive force on a PRD is very high, plasticity in the PRD occurs, which leads to its eventual destruction with increasing load.

  20. Pipeline welding goes mechanized

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beeson, R.

    1999-11-01

    Spread four has bugs in the cornfield--but not to worry. The bug referred to here is a mechanized welding bug, specifically a single welding head, computer-aided gas metal arc (GMAW) system from CRC-Evans Automatic Welding powered by a Miller Electric XMT{reg{underscore}sign} 304 inverter-based welding machine. The bug operator and owner of 32 inverters is Welded Construction, L.P., of Perrysburgh, Ohio. Spread four is a 147-mile stretch of the Alliance Pipeline system (Alliance) cutting through the cornfields of northeast Iowa. While used successfully in Canada and Europe for onshore and offshore pipeline construction for 30 years, this is the first large-scalemore » use of mechanized welding in the US on a cross-country pipeline. On longer, larger-diameter and thicker-wall pipe projects--the Alliance mainline has 1,844 miles of pipe, most of it 36-in. diameter with a 0.622-in. wall thickness--mechanized GMAW offers better productivity than manual shielded metal arc welding (SMAW). In addition, high-strength steels, such as the API 5L Grade X70 pipe used on the Alliance, benefit from the low-hydrogen content of certain solid and tubular wire electrodes.« less

  1. Responses of buried corrugated metal pipes to earthquakes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Davis, C.A.; Bardet, J.P.

    2000-01-01

    This study describes the results of field investigations and analyses carried out on 61 corrugated metal pipes (CMP) that were shaken by the 1994 Northridge earthquake. These CMPs, which include 29 small-diameter (below 107 cm) CMPs and 32 large-diameter (above 107 cm) CMPs, are located within a 10 km{sup 2} area encompassing the Van Normal Complex in the Northern San Fernando Valley, in Los Angeles, California. During the Northridge earthquake, ground movements were extensively recorded within the study area. Twenty-eight of the small-diameter CMPs performed well while the 32 large-diameter CMPs underwent performances ranging from no damage to complete collapse.more » The main cause of damage to the large-diameter CMPs was found to be the large ground strains. Based on this unprecedented data set, the factors controlling the seismic performance of the 32 large-diameter CMPs were identified and framed into a pseudostatic analysis method for evaluating the response of large diameter flexible underground pipes subjected to ground strain. The proposed analysis, which is applicable to transient and permanent strains, is capable of describing the observed performance of large-diameter CMPs during the 1994 Northridge earthquake. It indicates that peak ground velocity is a more reliable parameter for analyzing pipe damage than is peak ground acceleration. Results of this field investigation and analysis are useful for the seismic design and strengthening of flexible buried conduits.« less

  2. Multiple-Coil, Pulse-Induction Metal Detector

    NASA Technical Reports Server (NTRS)

    Lesky, Edward S.; Reid, Alan M.; Bushong, Wilton E.; Dickey, Duane P.

    1988-01-01

    Multiple-head, pulse-induction metal detector scans area of 72 feet squared with combination of eight detector heads, each 3 ft. square. Head includes large primary coil inducing current in smaller secondary coils. Array of eight heads enables searcher to cover large area quickly. Pulses applied to primary coil, induced in secondary coils measured to determine whether metal present within range of detector head. Detector designed for recovery of Space Shuttle debris.

  3. Feller/bunchers in plantations thinnings: factors affecting productivity.

    Treesearch

    Sharon A. Winsauer; James A. Mattson; Michael A. Thompson

    1984-01-01

    Computer simulation was used to identify possible areas for improving the design and operation of feller/bunchers for thinning closely spaced plantations. Some of the variables considered were average stand diameter, tree spacing, thinning pattern, operational machine speeds, and shear head accumulating capacity.

  4. Density Resolution Artifacts Encountered When Scanning Infant Heads With X-Ray Computed Tomography (CT)

    NASA Astrophysics Data System (ADS)

    Thompson, Joseph R.; M oore, Robert J.; Hinshaw, David B.; Hasso, Anton N.

    1982-12-01

    Density resolution the accuracy of CT numbers) is generally recognized by radiologists w'ao interpret Children's, CT to be very poor. A CT scanning phantom was made. in order to document the brain attenuation inaccuracies which do occur and also to derive normal brain attenuation values for varying sized heads, given. the skull diameters and thicknesses. In scanning' this phantom, other factors, some of equal importance, to small head size, were found to affect the Hounsfield numbers of brain. The phantom was scanned in order to determine the magnitude of these specific factors, using the GE 8800 model scanner. After head size (412 to 25, H), the variables of the head support (up to 15 H) and centering within the field of view (6-23 H) were of similar importance, for small heads. Kilovoltage, software, and machine drift were less, important, although only kVp settings, of 105 and 120 were employed. Manufacturers may improve CT number accuracy if they recognize the relative, magnitude of the various factors which alter measured attenuation.

  5. Breeding behavior and reproductive life history of the Neosho Madtom, Noturus placidus (Teleostei: Ictaluridae)

    USGS Publications Warehouse

    Bulger, Angela G.; Wilkinson, Christopher D.; Edds, David R.; Wildhaber, Mark L.

    2002-01-01

    The Neosho madtom, Noturus placidus, is a small catfish listed by the U. S. Fish and Wildlife Service as threatened. Little is known of its breeding biology and behavior because high turbidity and flow during its spawning season prevent direct observation in the field, and captive propagation has met with limited success. We held Neosho madtoms in laboratory aquaria in 1996 and 1998 to study sexual dimorphism during breeding season, courtship and nesting behavior, egg and clutch size, and embryological and larval development. We also attempted to induce spawning. Courtship behaviors were recorded on videotape, including “carousel” and “tail curl” displays in which the fish spun in circles, head to tail, then quivered, with the male's tail wrapped around the female's head. Three clutches were observed, all in nest cavities that had been excavated by the fish under a structure; one clutch (1996) consisted of approximately 60 eggs, with a mean chorion diameter of 3.1 mm, and two (1998) consisted of approximately 30 eggs, with mean diameter of 3.7 mm. In all situations, eggs hatched after eight or nine days, and yolk-sacs were fully depleted seven days later. One spawn (1998) occurred after two days of injection with synthetic hormone. Male parental care of eggs and larvae was observed in 1996. Larvae remained in the nest until yolk-sacs were absorbed, after which they dispersed throughout the tank. Dissection of two females that laid clutches in this study revealed previtellogenic eggs in the lumen of ovaries, with a mean chorion diameter of 0.9 mm. Swollen lips of males, distended abdomen of females, and differences in head shape, premaxillary tooth patch coloring, and genital papillae of breeding males and females were documented during spawning periods.

  6. Does oversizing an uncemented cup increase post-operative pain in primary total hip arthroplasty?

    PubMed

    Barrow, Jonathan A; Divecha, Hiren M; Panchani, Sunil; Boden, Richard; Porter, Martyn L; Board, Tim N

    2018-05-31

    It has been suggested that one of the factors related to persistent post-operative pain following total hip arthroplasty (THA) is to over sizing of the acetabular component. In order to investigate this potential issue, we retrospectively analysed a series of consecutive uncemented THA. We assessed the incidence of persistent post-operative pain and the size difference between the implanted acetabular component and the native femoral head. A total of 265 consecutive THAs were retrospectively identified. Standardised pre-operative radiographs were analysed using validated techniques to determine the native femoral head diameter. Post-operative standardised radiographs were reviewed and the acetabular orientation determined. Patients were sent postal questionnaires regarding their outcome and level of pain. Questionnaires were returned by 169 patients (189 hips, 71% response rate). A total of 17 were excluded due to inadequate radiographs., leaving 172 THA in the study group. The mean native femoral head (NFH) size was 47 mm. The most common implanted acetabular component size was 52 mm. The mean difference in cup to NFH diameter (delta) was 5.7 mm (range - 6.1 to 15.4 mm; 95% CI 5.3-6.2 mm). A delta of > 6 mm was found to be significant for predicting persistent post-operative pain (RR = 1.81; 95% CI 1.1-3.1; P = 0.027). Our study confirms that a delta of > 6 mm is associated with an increased risk of persistent post-operative pain following THA. We recommend pre-operative templating in all uncemented THA to ensure the planned acetabular component is no more than 6 mm larger than the NFH diameter.

  7. Resting myosin cross-bridge configuration in frog muscle thick filaments.

    PubMed

    Cantino, M; Squire, J

    1986-02-01

    Clear images of myosin filaments have been seen in shadowed freeze-fracture replicas of single fibers of relaxed frog semitendinosus muscles rapidly frozen using a dual propane jet freezing device. These images have been analyzed by optical diffraction and computer averaging and have been modelled to reveal details of the myosin head configuration on the right-handed, three-stranded helix of cross-bridges. Both the characteristic 430-A and 140-150-A repeats of the myosin cross-bridge array could be seen. The measured filament backbone diameter was 140-160 A, and the outer diameter of the cross-bridge array was 300 A. Evidence is presented that suggests that the observed images are consistent with a model in which both of the heads of one myosin molecule tilt in the same direction at an angle of approximately 50-70 degrees to the normal to the filament long axis and are slewed so that they lie alongside each other and their radially projected density lies along the three right-handed helical tracks. Any perturbation of the myosin heads away from their ideal lattice sites needed to account for x-ray reflections not predicted for a perfect helix must be essentially along the three helical tracks of cross-bridges. Little trace of the presence of non-myosin proteins could be seen.

  8. Morphological differences in parr of Atlantic salmon Salmo salar from three regions in Norway.

    PubMed

    Solem, O; Berg, O K

    2011-05-01

    Morphological characters were compared in parr (total length 33-166 mm) of Atlantic salmon Salmo salar sampled from eight wild populations in three regions, three in northern, two in the middle and three in southern Norway, covering a distance of 1700 km (from 70° N to 58° N). On the basis of morphological characters 94·6% of the individuals were correctly classified into the three regions. Discrimination between populations within these three regions also had a high degree of correct classification (89·0-95·8%). Principle component analysis identified largest differences to be in head characters, notably eye diameter and jawbone, with the smallest diameter and head size among the northernmost populations. Fish from the southern rivers had a deeper body form whereas fish from the middle region had larger heads and pectoral fins. This illustrates that S. salar already in the early parr stage has morphological traits, which can be used in discrimination between regions and populations and that these differences are discernible in spite of the volume of escaped farmed fish spawning in Norwegian rivers during the past 30 years. © 2011 The Authors. Journal of Fish Biology © 2011 The Fisheries Society of the British Isles.

  9. Water Powered Tools

    NASA Technical Reports Server (NTRS)

    1976-01-01

    Space Spin-Offs, Inc. under a contract with Lewis Research Center and Marshall Space Flight Center produced a new water-powered saw that cuts through concrete and steel plate reducing danger of explosion or electric shock in rescue and other operations. In prototype unit efficient water-powered turbine drives an 8 inch diameter grinding disk at 6,600 rpm. Exhaust water cools disk and workpiece quenching any sparks produced by cutting head. At maximum power, tool easily cuts through quarter inch steel plate. Adapter heads for chain saws, impact wrenches, heavy duty drills, and power hack saws can be fitted.

  10. Straddle design of spiral bevel and hypoid pinions and gears

    NASA Technical Reports Server (NTRS)

    Litvin, Faydor L.; Kuan, Chihping; Kieffer, Jonathan; Bossler, Robert; Handschuh, Robert F.

    1990-01-01

    The design of spiral bevel and hypoid gears that have a shaft extended from both sides of the cone apex (straddle design) is considered. A main difficulty of such a design is determining the length and diameter of the shaft that might be undercut by the head cutter during gear tooth generation. A method that determines the free space available for the gear shaft is proposed. The approach avoids collision between the shaft being designed and the head cutter during tooth generation. The approach is illustrated with a numerical example.

  11. High pressure fiber optic sensor system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Guida, Renato; Xia, Hua; Lee, Boon K

    2013-11-26

    The present application provides a fiber optic sensor system. The fiber optic sensor system may include a small diameter bellows, a large diameter bellows, and a fiber optic pressure sensor attached to the small diameter bellows. Contraction of the large diameter bellows under an applied pressure may cause the small diameter bellows to expand such that the fiber optic pressure sensor may measure the applied pressure.

  12. Inventory-based sensitivity analysis of the Large Tree Diameter Growth Submodel of the Southern Variant of the FVS

    Treesearch

    Giorgio Vacchiano; John D. Shaw; R. Justin DeRose; James N. Long

    2008-01-01

    Diameter increment is an important variable in modeling tree growth. Most facets of predicted tree development are dependent in part on diameter or diameter increment, the most commonly measured stand variable. The behavior of the Forest Vegetation Simulator (FVS) largely relies on the performance of the diameter increment model and the subsequent use of predicted dbh...

  13. High-Resolution Flow Logging for Hydraulic Characterization of Boreholes and Aquifer Flow Zones at Contaminated Bedrock Sites

    NASA Astrophysics Data System (ADS)

    Williams, J. H.; Johnson, C. D.; Paillet, F. L.

    2004-05-01

    In the past, flow logging was largely restricted to the application of spinner flowmeters to determine flow-zone contributions in large-diameter production wells screened in highly transmissive aquifers. Development and refinement of tool-measurement technology, field methods, and analysis techniques has greatly extended and enhanced flow logging to include the hydraulic characterization of boreholes and aquifer flow zones at contaminated bedrock sites. State-of-the-art in flow logging will be reviewed, and its application to bedrock-contamination investigations will be presented. In open bedrock boreholes, vertical flows are measured with high-resolution flowmeters equipped with flexible rubber-disk diverters fitted to the nominal borehole diameters to concentrate flow through the measurement throat of the tools. Heat-pulse flowmeters measure flows in the range of 0.05 to 5 liters per minute, and electromagnetic flowmeters measure flows in the range of 0.3 to 30 liters per minute. Under ambient and low-rate stressed (either extraction or injection) conditions, stationary flowmeter measurements are collected in competent sections of the borehole between fracture zones identified on borehole-wall images. Continuous flow, fluid-resistivity, and temperature logs are collected under both sets of conditions while trolling with a combination electromagnetic flowmeter and fluid tool. Electromagnetic flowmeters are used with underfit diverters to measure flow rates greater than 30 liters per minute and suppress effects of diameter variations while trolling. A series of corrections are applied to the flow-log data to account for the zero-flow response, bypass, trolling, and borehole-diameter biases and effects. The flow logs are quantitatively analyzed by matching simulated flows computed with a numerical model to measured flows by varying the hydraulic properties (transmissivity and hydraulic head) of the flow zones. Several case studies will be presented that demonstrate the integration of flow logging in site-characterization activities framework; 2) evaluate cross-connection effects and determine flow-zone contributions to water-quality samples from open boreholes; and 3) design discrete-zone hydraulic tests and monitoring-well completions.

  14. The principle of low frictional torque in the Charnley total hip replacement.

    PubMed

    Wroblewski, B M; Siney, P D; Fleming, P A

    2009-07-01

    The design of the Charnley total hip replacement follows the principle of low frictional torque. It is based on the largest possible difference between the radius of the femoral head and that of the outer aspect of the acetabular component. The aim is to protect the bone-cement interface by movement taking place at the smaller radius, the articulation. This is achieved in clinical practice by a 22.225 mm diameter head articulating with a 40 mm or 43 mm diameter acetabular component of ultra-high molecular weight polyethylene. We compared the incidence of aseptic loosening of acetabular components with an outer diameter of 40 mm and 43 mm at comparable depths of penetration with a mean follow-up of 17 years (1 to 40). In cases with no measurable wear none of the acetabular components were loose. With increasing acetabular penetration there was an increased incidence of aseptic loosening which reflected the difference in the external radii, with 1.5% at 1 mm, 8.8% at 2 mm, 9.7% at 3 mm and 9.6% at 4 mm of penetration in favour of the larger 43 mm acetabular component. Our findings support the Charnley principle of low frictional torque. The level of the benefit is in keeping with the predicted values.

  15. Reference values of anthropometric measurements in Dutch children. The Oosterwolde Study.

    PubMed

    Gerver, W J; Drayer, N M; Schaafsma, W

    1989-03-01

    In the period 1979-1980 the following anthropometric measurements were recorded in 2351 healthy Dutch children from 0-17 years of age: height, weight, sitting height, arm span, lengths of upper-arm, lower-arm and hand, tibial length, foot length, biacromial diameter, biiliacal diameter, and head circumference. Corresponding percentile values were constructed on the basis of normality assumptions, the mean and standard deviation at age t being determined by a cubic spline approximation. The results are compared with other studies and given in the form of growth charts.

  16. Mitochondrial DNA typing from human axillary, pubic and head hair shafts - success rates and sequence comparisons.

    PubMed

    Pfeiffer, H; Hühne, J; Ortmann, C; Waterkamp, K; Brinkmann, B

    1999-01-01

    The analysis of mitochondrial DNA (mtDNA) from shed hairs has gained high importance in forensic casework since telogen hairs are one of the most common types of evidence left at the crime scene. In this systematic study of hair shafts from 20 individuals, the correlation of mtDNA recovery with hair morphology (length, diameter, volume, colour), with sex, and with body localisation (head, armpit, pubis) was investigated. The highest average success rate of hypervariable region 1 (HV 1) sequencing was found in head hair shafts (75%) followed by pubic (66%) and axillary hair shafts (52%). No statistically significant correlation between morphological parameters or sex and the success rate of sequencing was found. MtDNA sequences of buccal cells, head, pubic and axillary hair shafts did not show intraindividual differences. Heteroplasmic base positions were observed neither in the hair shafts nor in control samples of buccal cells.

  17. SU-F-T-538: CyberKnife with MLC for Treatment of Large Volume Tumors: A Feasibility Study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bichay, T; Mayville, A

    2016-06-15

    Purpose: CyberKnife is a well-documented modality for SRS and SBRT treatments. Typical tumors are small and 1–5 fractions are usually used. We determined the feasibility of using CyberKnife, with an InCise multileaf collimator option, for larger tumors undergoing standard dose and fractionation. The intent was to understand the limitation of using this modality for other external beam radiation treatments. Methods: Five tumors from different anatomical sites with volumes from 127.8 cc to 1,320.5 cc were contoured and planned on a Multiplan V5.1 workstation. The target average diameter ranged from 7 cm to 13 cm. The dose fractionation was 1.8–2.0 Gy/fractionmore » and 25–45 fractions for total doses of 45–81 Gy. The sites planned were: pancreas, head and neck, prostate, anal, and esophagus. The plans were optimized to meet conventional dose constraints based on various RTOG protocols for conventional fractionation. Results: The Multiplan treatment planning system successfully generated clinically acceptable plans for all sites studied. The resulting dose distributions achieved reasonable target coverage, all greater than 95%, and satisfactory normal tissue sparing. Treatment times ranged from 9 minutes to 38 minutes, the longest being a head and neck plan with dual targets receiving different doses and with multiple adjacent critical structures. Conclusion: CyberKnife, with the InCise multileaf collimation option, can achieve acceptable dose distributions in large volume tumors treated with conventional dose and fractionation. Although treatment times are greater than conventional accelerator time; target coverage and dose to critical structures can be kept within a clinically acceptable range. While time limitations exist, when necessary CyberKnife can provide an alternative to traditional treatment modalities for large volume tumors.« less

  18. Vision in semi-aquatic snakes: Intraocular morphology, accommodation, and eye: Body allometry

    NASA Astrophysics Data System (ADS)

    Plylar, Helen Bond

    Vision in vertebrates generally relies on the refractive power of the cornea and crystalline lens to facilitate vision. Light from the environment enters the eye and is refracted by the cornea and lens onto the retina for production of an image. When an animal with a system designed for air submerges underwater, the refractive power of the cornea is lost. Semi-aquatic animals (e.g., water snakes, turtles, aquatic mammals) must overcome this loss of corneal refractive power through visual accommodation. Accommodation relies on change of the position or shape of the lens to change the focal length of the optical system. Intraocular muscles and fibers facilitate lenticular displacement and deformation. Snakes, in general, are largely unstudied in terms of visual acuity and intraocular morphology. I used light microscopy and scanning electron microscopy to examine differences in eye anatomy between five sympatric colubrid snake species (Nerodia cyclopion, N. fasciata, N. rhombifer, Pantherophis obsoletus, and Thamnophis proximus) from Southeast Louisiana. I discovered previously undescribed structures associated with the lens in semi-aquatic species. Photorefractive methods were used to assess refractive error. While all species overcame the expected hyperopia imposed by submergence, there was interspecific variation in refractive error. To assess scaling of eye size with body size, I measure of eye size, head size, and body size in Nerodia cyclopion and N. fasciata from the SLU Vertebrate Museum. In both species, body size increases at a significantly faster rate than head size and eye size (negative allometry). Small snakes have large eyes relative to body size, and large snakes have relatively small eyes. There were interspecific differences in scaling of eye size with body size, where N. fasciata had larger eye diameter, but N. cyclopion had longer eyes (axial length).

  19. Tribology of alternative bearings.

    PubMed

    Fisher, John; Jin, Zhongmin; Tipper, Joanne; Stone, Martin; Ingham, Eileen

    2006-12-01

    The tribological performance and biological activity of the wear debris produced has been compared for highly cross-linked polyethylene, ceramic-on-ceramic, metal-on-metal, and modified metal bearings in a series of in vitro studies from a single laboratory. The functional lifetime demand of young and active patients is 10-fold greater than the estimated functional lifetime of traditional polyethylene. There is considerable interest in using larger diameter heads in these high demand patients. Highly cross-linked polyethylene show a four-fold reduction in functional biological activity. Ceramic-on-ceramic bearings have the lowest wear rates and least reactive wear debris. The functional biological activity is 20-fold lower than with highly cross-linked polyethylene. Hence, ceramic-on-ceramic bearings address the tribological lifetime demand of highly active patients. Metal-on-metal bearings have substantially lower wear rates than highly cross-linked polyethylene and wear decreases with head diameter. Bedding in wear is also lower with reduced radial clearance. Differential hardness ceramic-on-metal bearings and the application of ceramic-like coatings reduce metal wear and ion levels.

  20. Giant basal cell carcinoma of the face: surgical management and challenges for reconstruction.

    PubMed

    Maimaiti, A; Mijiti, A; Yarbag, A; Moming, A

    2016-02-01

    Giant basal cell carcinoma, in which the tumour measures 5 cm or greater in diameter, is a very rare skin malignancy that accounts for less than 1 per cent of all basal cell tumours. Very few studies have reported on the incidence, resection and reconstruction of this lesion worldwide. In total, 17 patients with giant basal cell carcinoma of the head and neck region underwent surgical excision and reconstruction at our hospital. Medical charts were retrospectively reviewed and analysed. The lesion was usually in the forehead, eyelid, lips or nasal-cheek region. The greatest diameter ranged from 5 to 11 cm, with 5-6 cm being the most common size at the time of presentation. All patients had their tumour resected and reconstructed in a single-stage procedure, mostly with a local advancement flap, and with no post-operative flap failure. Giant basal cell carcinoma of the head and neck can be successfully treated with a local flap in a single-stage approach.

  1. Small biparietal diameter and head circumference are part of the phenotype instead of independent prognostic markers in fetuses with spinal dysraphism.

    PubMed

    Cuppen, Inge; de Bruijn, Dagmar; Geerdink, Niels; Rotteveel, Jan J; Willemsen, Michèl A A P; van Vugt, John M G; Pasman, Jaco W; Roeleveld, Nel

    2015-01-01

    The aim of this retrospective study was to assess the fetal biparietal diameter (BPD) and head circumference (HC) in the second trimester of pregnancy in fetuses with open spinal dysraphism. BPD and HC were measured at 16-26 weeks in 74 fetuses with open spinal dysraphism and compared with reference values. BPD was smaller in fetuses with open spinal dysraphism. Of all cases with open spinal dysraphism, 62.2% had a BPD <3rd percentile and 79.7% had a BPD <10th percentile. Of all patients, 54.1% had an HC <3rd percentile and 74.3% had an HC <10th percentile. Almost all fetuses with open neural tube defects have a smaller BPD and HC at 16-26 weeks compared with reference values, which implicates that this is part of the phenotype of children with open spinal dysraphism instead of an independent prognostic marker for a poor cognitive outcome. © 2014 S. Karger AG, Basel.

  2. 75 FR 38989 - Welded Large Diameter Line Pipe From Japan: Notice of Rescission of Antidumping Duty...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-07

    ... Pipe From Japan: Notice of Rescission of Antidumping Duty Administrative Review AGENCY: Import... antidumping duty order on welded large diameter line pipe from Japan. The review covers 4 producers/exporters of welded large diameter line pipe from Japan, which are, JFE Steel Corporation, Nippon Steel...

  3. Purification of 1.9-nm-diameter semiconducting single-wall carbon nanotubes by temperature-controlled gel-column chromatography and its application to thin-film transistor devices

    NASA Astrophysics Data System (ADS)

    Thendie, Boanerges; Omachi, Haruka; Hirotani, Jun; Ohno, Yutaka; Miyata, Yasumitsu; Shinohara, Hisanori

    2017-06-01

    Large-diameter semiconductor single-wall carbon nanotubes (s-SWCNTs) have superior mobility and conductivity to small-diameter s-SWCNTs. However, the purification of s-SWCNTs with diameters larger than 1.6 nm by gel filtration has been difficult owing to the low selectivity of the conventional purification method in these large-diameter regions. We report a combination of temperature-controlled gel filtration and the gradient elution technique that we developed to enrich a high-purity s-SWCNT with a diameter as large as 1.9 nm. The thin-film transistor (TFT) device using the 1.9-nm-diameter SWCNT shows an average channel mobility of 23.7 cm2 V-1 s-1, which is much higher than those of conventional SWCNT-TFTs with smaller-diameters of 1.5 and 1.4 nm.

  4. Analytical correlation of centrifugal compressor design geometry for maximum efficiency with specific speed

    NASA Technical Reports Server (NTRS)

    Galvas, M. R.

    1972-01-01

    Centrifugal compressor performance was examined analytically to determine optimum geometry for various applications as characterized by specific speed. Seven specific losses were calculated for various combinations of inlet tip-exit diameter ratio, inlet hub-tip diameter ratio, blade exit backsweep, and inlet-tip absolute tangential velocity for solid body prewhirl. The losses considered were inlet guide vane loss, blade loading loss, skin friction loss, recirculation loss, disk friction loss, vaneless diffuser loss, and vaned diffuser loss. Maximum total efficiencies ranged from 0.497 to 0.868 for a specific speed range of 0.257 to 1.346. Curves of rotor exit absolute flow angle, inlet tip-exit diameter ratio, inlet hub-tip diameter ratio, head coefficient and blade exit backsweep are presented over a range of specific speeds for various inducer tip speeds to permit rapid selection of optimum compressor size and shape for a variety of applications.

  5. All fiber passively Q-switched laser

    DOEpatents

    Soh, Daniel B. S.; Bisson, Scott E

    2015-05-12

    Embodiments relate to an all fiber passively Q-switched laser. The laser includes a large core doped gain fiber having a first end. The large core doped gain fiber has a first core diameter. The laser includes a doped single mode fiber (saturable absorber) having a second core diameter that is smaller than the first core diameter. The laser includes a mode transformer positioned between a second end of the large core doped gain fiber and a first end of the single mode fiber. The mode transformer has a core diameter that transitions from the first core diameter to the second core diameter and filters out light modes not supported by the doped single mode fiber. The laser includes a laser cavity formed between a first reflector positioned adjacent the large core doped gain fiber and a second reflector positioned adjacent the doped single mode fiber.

  6. Selective control of small versus large diameter axons using infrared laser light (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Lothet, Emilie H.; Shaw, Kendrick M.; Horn, Charles C.; Lu, Hui; Wang, Yves T.; Jansen, E. Duco; Chiel, Hillel J.; Jenkins, Michael W.

    2016-03-01

    Sensory information is conveyed to the central nervous system via small diameter unmyelinated fibers. In general, smaller diameter axons have slower conduction velocities. Selective control of such fibers could create new clinical treatments for chronic pain, nausea in response to chemo-therapeutic agents, or hypertension. Electrical stimulation can control axonal activity, but induced axonal current is proportional to cross-sectional area, so that large diameter fibers are affected first. Physiologically, however, synaptic inputs generally affect small diameter fibers before large diameter fibers (the size principle). A more physiological modality that first affected small diameter fibers could have fewer side effects (e.g., not recruiting motor axons). A novel mathematical analysis of the cable equation demonstrates that the minimum length along the axon for inducing block scales with the square root of axon diameter. This implies that the minimum length along an axon for inhibition will scale as the square root of axon diameter, so that lower radiant exposures of infrared light will selectively affect small diameter, slower conducting fibers before those of large diameter. This prediction was tested in identified neurons from the marine mollusk Aplysia californica. Radiant exposure to block a neuron with a slower conduction velocity (B43) was consistently lower than that needed to block a faster conduction velocity neuron (B3). Furthermore, in the vagus nerve of the musk shrew, lower radiant exposure blocked slow conducting fibers before blocking faster conducting fibers. Infrared light can selectively control smaller diameter fibers, suggesting many novel clinical treatments.

  7. AAFE large deployable antenna development program: Executive summary

    NASA Technical Reports Server (NTRS)

    1977-01-01

    The large deployable antenna development program sponsored by the Advanced Applications Flight Experiments of the Langley Research Center is summarized. Projected user requirements for large diameter deployable reflector antennas were reviewed. Trade-off studies for the selection of a design concept for 10-meter diameter reflectors were made. A hoop/column concept was selected as the baseline concept. Parametric data are presented for 15-meter, 30-meter, and 100-meter diameters. A 1.82-meter diameter engineering model which demonstrated the feasiblity of the concept is described.

  8. Numerical analysis of specific absorption rate in the human head due to a 13.56 MHz RFID-based intra-ocular pressure measurement system

    NASA Astrophysics Data System (ADS)

    Hirtl, Rene; Schmid, Gernot

    2013-09-01

    A modern wireless intra-ocular pressure monitoring system, based on 13.56 MHz inductively coupled data transmission, was dosimetrically analyzed with respect to the specific absorption rate (SAR) induced inside the head and the eye due to the electromagnetic field exposure caused by the reader antenna of the transmission system. The analysis was based on numerical finite difference time domain computations using a high resolution anatomical eye model integrated in a modern commercially available anatomical model of a male head. Three different reader antenna configurations, a 7-turn elliptic (30 mm × 50 mm) antenna at 12 mm distance from the eye, a flexible circular antenna (60 mm diameter, 8 turns on 2 mm substrate) directly attached to the skin, and a circular 7-turn antenna (30 mm diameter at 12 mm distance to the eye) were analyzed, respectively. Possible influences of the eye-lid status (closed or opened) and the transponder antenna contained in a contact lens directly attached to the eye were taken into account. The results clearly demonstrated that for typical reader antenna currents required for proper data transmission, the SAR values remain far below the limits for localized exposure of the head, as defined by the International Commission for Non-Ionizing Radiation Protection. Particularly the induced SAR inside the eye was found to be substantially (orders of magnitudes for typical reader antenna currents in the order of 1 A turn) below values which have been reported to be critical with respect to thermally induced adverse health effects in eye tissues.

  9. [Intra-prosthetic dislocation of the Bousquet dual mobility socket].

    PubMed

    Lecuire, F; Benareau, I; Rubini, J; Basso, M

    2004-05-01

    The Bousquet system is a dual mobility head-polyethylene polyethylene-metal cup socket. The polyethylene insert retaining the femoral head moves in the noncemented metal cup, increasing both mobility and stability. Between 1989 and 1997, seven cases of intra-prosthetic dislocation (six patients) were observed. The femoral head escaped from the polyethylene insert due to wear. On the average, this complication occurred ten Years after implantation. Risk of dislocation was high in six of the seven hips. All patients had a large sized stem screwed into the femoral neck. There was a characteristic radiological aspect with loss of the concentric head metal cup configuration. The head was applied against the upper wall of the metal cup. Surgical replacement was undertaken early in six patients by simply changing the insert without modifying the other stable components. Outcome remained good at three to eight Years. One patient underwent late surgery. The insert and the cup were replaced with a classical implant. Functional outcome was good but recurrent dislocation occurred. At mid-term, intra-prosthetic dislocation of dual mobility sockets appears to be exceptional. Dislocation results from polyethylene wear leading to failure of the insert to retain the prosthetic head. Wear is favored by direct phenomena (direct contact between neck and insert which can occur early if there is a small difference in the head and neck diameters) or indirect phenomena (factors limiting polyethylene metal-cup mobility). Surgical treatment is necessary. If undertaken early, replacement with a modular head and insert can be sufficient if the prosthesis has not loosened but the metal cup may have to be replaced in the event of metal-metal contact between the head and the cup. Prosthesis loosening, wear of the metal cup, or an identified cause of dislocation imply replacing the failing implants. Implantation of the dual mobility system is particularly interesting for patients with a high risk of dislocation or a chronically unstable hip prosthesis. Careful technique is required to reduce or retard the risk of intra-prosthetic dislocation. Intra-prosthetic dislocation of a dual mobility socket is an exceptional complication at mid-term. Surgical treatment is required but may be limited to simple insert replacement. Systematic use of this type of implant in young subjects must be carefully examined, but for us, the risk of dislocation does not outweigh the advantages of this original concept of dual mobility. This type of socket remains an useful preventive technique for high-risk hips or for curative treatment of recurrent dislocation.

  10. SU-E-J-215: Towards MR-Only Image Guided Identification of Calcifications and Brachytherapy Seeds: Application to Prostate and Breast LDR Implant Dosimetry

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Elzibak, A; Fatemi-Ardekani, A; Soliman, A

    Purpose: To identify and analyze the appearance of calcifications and brachytherapy seeds on magnitude and phase MRI images and to investigate whether they can be distinguished from each other on corrected phase images for application to prostate and breast low dose rate (LDR) implant dosimetry. Methods: An agar-based gel phantom containing two LDR brachytherapy seeds (Advantage Pd-103, IsoAid, 0.8mm diameter, 4.5mm length) and two spherical calcifications (large: 7mm diameter and small: 4mm diameter) was constructed and imaged on a 3T Philips MR scanner using a 16-channel head coil and a susceptibility weighted imaging (SWI) sequence (2mm slices, 320mm FOV, TR/more » TE= 26.5/5.3ms, 15 degree flip angle). The phase images were unwrapped and corrected using a 32×32, 2D Hanning high pass filter to remove background phase noise. Appearance of the seeds and calcifications was assessed visually and quantitatively using Osirix (http://www.osirix-viewer.com/). Results: As expected, calcifications and brachytherapy seeds appeared dark (hypointense) relative to the surrounding gel on the magnitude MRI images. The diameter of each seed without the surrounding artifact was measured to be 0.1 cm on the magnitude image, while diameters of 0.79 and 0.37 cm were measured for the larger and smaller calcifications, respectively. On the corrected phase images, the brachytherapy seeds and the calcifications appeared bright (hyperintense). The diameter of the seeds was larger on the phase images (0.17 cm) likely due to the dipole effect. Conclusion: MRI has the best soft tissue contrast for accurate organ delineation leading to most accurate implant dosimetry. This work demonstrated that phase images can potentially be useful in identifying brachytherapy seeds and calcifications in the prostate and breast due to their bright appearance, which helps in their visualization and quantification for accurate dosimetry using MR-only. Future work includes optimizing phase filters to best identify and delineate seeds and calcifications.« less

  11. 76 FR 7815 - Certain Large Diameter Carbon and Alloy Seamless Standard, Line, and Pressure Pipe (Over 41/2

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-11

    ... DEPARTMENT OF COMMERCE International Trade Administration [A-588-850] Certain Large Diameter Carbon and Alloy Seamless Standard, Line, and Pressure Pipe (Over 4\\1/2\\ Inches) From Japan: Extension of... administrative review of the antidumping duty order on certain large diameter carbon and alloy seamless standard...

  12. The accuracy of body mass prediction for elderly specimens: Implications for paleoanthropology and legal medicine.

    PubMed

    Chevalier, Tony; Lefèvre, Philippe; Clarys, Jan Pieter; Beauthier, Jean-Pol

    2016-10-01

    Different practices in paleoanthropology and legal medicine raise questions concerning the robustness of body mass (BM) prediction. Integrating personal identification from body mass estimation with skeleton is not a classic approach in legal medicine. The originality of our study is the use of an elderly sample in order to push prediction methods to their limits and to discuss about implications in paleoanthropology and legal medicine. The aim is to observe the accuracy of BM prediction in relation to the body mass index (BMI, index of classification) using five femoral head (FH) methods and one shaft (FSH) method. The sample is composed of 41 dry femurs obtained from dissection where age (c. 82 years) and gender are known, and weight (c. 59.5 kg) and height are measured upon admission to the body leg service. We show that the estimation of the mean BM of the elderly sample is not significantly different to the real mean BM when the appropriate formula is used for the femoral head diameter. In fact, the best prediction is obtained with the McHenry formula (1992), which was based on a sample with an equivalent average mass to that of our sample. In comparison, external shaft diameters, which are known to be more influenced by mechanical stimuli than femoral head diameters, yield less satisfactory results with the McHenry formula (1992) for shaft diameters. Based on all the methods used and the distinctive selected sample, overestimation (always observed with the different femoral head methods) can be restricted to 1.1%. The observed overestimation with the shaft method can be restricted to 7%. However, the estimation of individual BM is much less reliable. The BMI has a strong impact on the accuracy of individual BM prediction, and is unquestionably more reliable for individuals with normal BMI (9.6% vs 16.7% for the best prediction error). In this case, the FH method is also the better predictive method but not if we integrate the total sample (i.e., the FSH method is better with more varied BMI). Finally, the estimation of the mean BM of a sample can be used with more confidence compared to the estimation of individual BM. The former is very useful in an evolutionary perspective whereas the latter should be used in keeping with the information gathered on the studied specimen in order to reduce prediction errors. Finally, the BM estimation can be a parameter to consider for personal identification. Copyright © 2016 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

  13. The Development of a Pirani Vacuum Gauge with a Platinum Wire in the J-PARC 3-GeV Rapid Cycling Synchrotron

    NASA Astrophysics Data System (ADS)

    Ogiwara, Norio; Hikichi, Yusuke; Yoshinari, Yoji

    The back pressure of Turbo-Molecular Pumps (TMPs) is constantly monitored using Pirani gauges at J-PARC (Japan Proton Accelerator Complex) RCS (3-GeV Rapid Cycling Synchrotron) where they are used not only in rough pumping but also evacuations during beam operations. The gauge head needs to be very resistant to vibration and abrupt air inlet etc. in minimizing exposure to radiation during maintenance and hence a 50 μm in diameter W wire was adopted as the filament. This type of Pirani gauge has worked well in monitoring the back pressure of the TMP but it has become difficult to measure the low pressure of less than several Pa with the gauge, which may have been due to changes in the emissivity of the W surface. An attempt was therefore made to develop a gauge head made of Pt wire in allowing pressures as low as 0.1 Pa to be measured. Platinum is one of the best possible materials to use because it is very stable against oxidization. However, ordinary Pt gauge heads are rather weak when it comes to vibrations and abrupt air inlet due to its low tensile strength. In order to improve its toughness the filament was composed of twelve 100 μm in diameter Pt wires that were 65 mm long, resulting in it being capable of enduring a force of 25 N. All the wires were welded in series on metal poles in two separate glass plates, with the poles being electrically insulated. This resulted in the filament, 78 cm long and about 10 Ω at room temperature, being containable in a 5 cm in diameter and 10 cm long cylindrical envelope. The output from the gauge head was then examined as a function of pressure under constant current as the plan was for it to be controlled using the constant current method. Confirmation then took place that the pressures of 0.1 Pa up to 103 Pa were measurable with the gauge using current control in such way that the set value increased with pressure increases in three stages.

  14. Brain Perfusion and Arterial Blood Flow Velocity During Prolonged Body Tilting.

    PubMed

    Montero, David; Rauber, Sven

    2016-08-01

    It remains unknown whether brain perfusion is preserved and mirrored by middle cerebral blood flow velocity (MCA BFV) during prolonged changes in body posture. Herein, we examined the impact of sustained (180 min) 30° head-up (HUT) and head-down (HDT) tilt on brain perfusion, as determined by MCA BFV and blood flow in the extracranial arteries. In 10 healthy male subjects, arterial diameters, BFVs, and blood flows were determined in the left internal carotid (ICA) and vertebral (VA) arteries using duplex Doppler ultrasound in supine rest, and 5, 20, 60, 120, and 180 min following 30° HUT and HDT. MCA BFV was recorded throughout with transcranial Doppler ultrasound. ICA as well as VA diameters and blood flows were unaltered during HUT. Likewise, brain blood flow and MCA BFV were preserved with HUT. In the HDT protocol, ICA and VA diameters were gradually increased, although ICA, VA, and brain blood flows were preserved. MCA BFV was progressively reduced during HDT. In addition, MCA BFV was positively associated with ICA BFV (β = 0.9) and negatively associated with ICA diameter (β = -125.5). MCA BFV was positively associated with brain blood flow during HUT (β = 0.2) but not HDT. Brain perfusion is preserved whereas MCA BFV is progressively decreased and associated with extracranial arterial BFV during sustained 30° HDT. Therefore, MCA BFV may not be a surrogate of brain perfusion in conditions including prolonged HDT. Montero D, Rauber S. Brain perfusion and arterial blood flow velocity during prolonged body tilting. Aerosp Med Hum Perform. 2016; 87(8):682-687.

  15. Controlled growth of well-aligned carbon nanotubes with large diameters

    NASA Astrophysics Data System (ADS)

    Wang, Xianbao; Liu, Yunqi; Zhu, Daoben

    2001-06-01

    Well-aligned carbon nanotubes (CNTs) with large diameters (25-200 nm) were synthesized by pyrolysis of iron(II) phthalocyanine. The outer diameter up to 218.5 nm and the length of the well-aligned CNTs can be systematically controlled by varying the growth time. A tube-in-tube nano-structure with large and small diameters of 176 and 16.7 nm, respectively, was found. The grain sizes of the iron catalyst play an important role in controlling the CNT diameters. These results are of great importance to design new aligned CNT-based electron field emitters in the potential application of panel displays.

  16. Is the track of the Yellowstone hotspot driven by a deep mantle plume? — Review of volcanism, faulting, and uplift in light of new data

    NASA Astrophysics Data System (ADS)

    Pierce, Kenneth L.; Morgan, Lisa A.

    2009-11-01

    Geophysical imaging of a tilted mantle plume extending at least 500 km beneath the Yellowstone caldera provides compelling support for a plume origin of the entire Yellowstone hotspot track back to its inception at 17 Ma with eruptions of flood basalts and rhyolite. The widespread volcanism, combined with a large volume of buoyant asthenosphere, supports a plume head as an initial phase. Estimates of the diameter of the plume head suggest it completely spanned the upper mantle and was fed from sources beneath the transition zone, We consider a mantle-plume depth to at least 1,000 km to best explain the large scale of features associated with the hotspot track. The Columbia River-Steens flood basalts form a northward-migrating succession consistent with the outward spreading of a plume head beneath the lithosphere. The northern part of the inferred plume head spread (pancaked) upward beneath Mesozoic oceanic crust to produce flood basalts, whereas basalt melt from the southern part intercepted and melted Paleozoic and older crust to produce rhyolite from 17 to 14 Ma. The plume head overlapped the craton margin as defined by strontium isotopes; westward motion of the North American plate has likely "scraped off" the head from the plume tail. Flood basalt chemistries are explained by delamination of the lithosphere where the plume head intersected this cratonic margin. Before reaching the lithosphere, the rising plume head apparently intercepted the east-dipping Juan de Fuca slab and was deflected ~ 250 km to the west; the plume head eventually broke through the slab, leaving an abruptly truncated slab. Westward deflection of the plume head can explain the anomalously rapid hotspot movement of 62 km/m.y. from 17 to 10 Ma, compared to the rate of ~ 25 km/m.y. from 10 to 2 Ma. A plume head-to-tail transition occurred in the 14-to-10-Ma interval in the central Snake River Plain and was characterized by frequent (every 200-300 ka for about 2 m.y. from 12.7 to 10.5 Ma) "large volume (> 7000 km 3)", and high temperature rhyolitic eruptions (> 1000 °C) along a ~ 200-km-wide east-west band. The broad transition area required a heat source of comparable area. Differing characteristics of the volcanic fields here may in part be due to variations in crustal composition but also may reflect development in differing parts of an evolving plume where the older fields may reflect the eruption from several volcanic centers located above very large and extensive rhyolitic magma chamber(s) over the detached plume head while the younger fields may signal the arrival of the plume tail intercepting and melting the lithosphere and generating a more focused rhyolitic magma chamber. The three youngest volcanic fields of the hotspot track started with large ignimbrite eruptions at 10.21, 6.62, and 2.05 Ma. They indicate hotspot migration N55° E at ~ 25 km/m.y. compatible in direction and velocity with the North American Plate motion. The Yellowstone Crescent of High Terrain (YCHT) flares outward ahead of the volcanic progression in a pattern similar to a bow-wave, and thus favors a sub-lithospheric driver. Estimates of YCHT-uplift rates are between 0.1 and 0.4 mm/yr. Drainage divides have migrated northeastward with the hotspot. The Continental Divide and a radial drainage pattern now centers on the hotspot. The largest geoid anomaly in the conterminous U.S. is also centered on Yellowstone and, consistent with uplift above a mantle plume. Bands of late Cenozoic faulting extend south and west from Yellowstone. These bands are subdivided into belts based both on recency of offset and range-front height. Fault history within these belts suggests the following pattern: Belt I — starting activity but little accumulated offset; Belt II — peak activity with high total offset and activity younger than 14 ka; Belt III — waning activity with large offset and activity younger than 140 ka; and Belt IV — apparently dead on substantial range fronts (south side of the eastern Snake River Plain only). These belts of fault activity have migrated northeast in tandem with the adjacent hotspot volcanism. On the southern arm of the YCHT, fault activity occurs on the inner, western slope consistent with driving by gravitational potential energy, whereas faulting has not started on the eastern, outer, more compressional slope. Range fronts increase in height and steepness northeastward along the southern-fault band. Both the belts of faulting and the YCHT are asymmetrical across the volcanic hotspot track, flaring out 1.6 times more on the south than the north side. This and the southeast tilt of the Yellowstone plume may reflect southeast flow of the upper mantle.

  17. SU-G-JeP2-13: Spatial Accuracy Evaluation for Real-Time MR Guided Radiation Therapy Using a Novel Large-Field MRI Distortion Phantom

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Antolak, A; Bayouth, J; Bosca, R

    Purpose: Evaluate a large-field MRI phantom for assessment of geometric distortion in whole-body MRI for real-time MR guided radiation therapy. Methods: A prototype CIRS large-field MRI distortion phantom consisting of a PMMA cylinder (33 cm diameter, 30 cm length) containing a 3D-printed orthogonal grid (3 mm diameter rods, 20 mm apart), was filled with 6 mM NiCl{sub 2} and 30 mM NaCl solution. The phantom was scanned at 1.5T and 3.0T on a GE HDxt and Discovery MR750, respectively, and at 0.35T on a ViewRay system. Scans were obtained with and without 3D distortion correction to demonstrate the impact ofmore » such corrections. CT images were used as a reference standard for analysis of geometric distortion, as determined by a fully automated gradient-search method developed in Matlab. Results: 1,116 grid points distributed throughout a cylindrical volume 28 cm in diameter and 16 cm in length were identified and analyzed. With 3D distortion correction, average/maximum displacements for the 1.5, 3.0, and 0.35T systems were 0.84/2.91, 1.00/2.97, and 0.95/2.37 mm, respectively. The percentage of points with less than (1.0, 1.5, 2.0 mm) total displacement were (73%, 92%, 97%), (54%, 85%, 97%), and (55%, 90%, 99%), respectively. A reduced scan volume of 20 × 20 × 10 cm{sup 3} (representative of a head and neck scan volume) consisting of 420 points was also analyzed. In this volume, the percentage of points with less than (1.0, 1.5, 2.0 mm) total displacement were (90%, 99%, 100%), (63%, 95%, 100%), and (75%, 96%, 100%), respectively. Without 3D distortion correction, average/maximum displacements were 1.35/3.67, 1.67/4.46, and 1.51/3.89 mm, respectively. Conclusion: The prototype large-field MRI distortion phantom and developed software provide a thorough assessment of 3D spatial distortions in MRI. The distortions measured were acceptable for RT applications, both for the high field strengths and the system configuration developed by ViewRay.« less

  18. Apparatus for measuring surface particulate contamination

    DOEpatents

    Woodmansee, Donald E.

    2002-01-01

    An apparatus for measuring surface particulate contamination includes a tool for collecting a contamination sample from a target surface, a mask having an opening of known area formed therein for defining the target surface, and a flexible connector connecting the tool to the mask. The tool includes a body portion having a large diameter section defining a surface and a small diameter section extending from the large diameter section. A particulate collector is removably mounted on the surface of the large diameter section for collecting the contaminants. The tool further includes a spindle extending from the small diameter section and a spool slidingly mounted on the spindle. A spring is disposed between the small diameter section and the spool for biasing the spool away from the small diameter section. An indicator is provided on the spindle so as to be revealed when the spool is pressed downward to compress the spring.

  19. Fetal head detection and measurement in ultrasound images by an iterative randomized Hough transform

    NASA Astrophysics Data System (ADS)

    Lu, Wei; Tan, Jinglu; Floyd, Randall C.

    2004-05-01

    This paper describes an automatic method for measuring the biparietal diameter (BPD) and head circumference (HC) in ultrasound fetal images. A total of 217 ultrasound images were segmented by using a K-Mean classifier, and the head skull was detected in 214 of the 217 cases by an iterative randomized Hough transform developed for detection of incomplete curves in images with strong noise without user intervention. The automatic measurements were compared with conventional manual measurements by sonographers and a trained panel. The inter-run variations and differences between the automatic and conventional measurements were small compared with published inter-observer variations. The results showed that the automated measurements were as reliable as the expert measurements and more consistent. This method has great potential in clinical applications.

  20. HEXPANDO Expanding Head for Fastener-Retention Hexagonal Wrench

    NASA Technical Reports Server (NTRS)

    Bishop, John

    2011-01-01

    The HEXPANDO is an expanding-head hexagonal wrench designed to retain fasteners and keep them from being dislodged from the tool. The tool is intended to remove or install socket-head cap screws (SHCSs) in remote, hard-to-reach locations or in circumstances when a dropped fastener could cause damage to delicate or sensitive hardware. It is not intended for application of torque. This tool is made of two assembled portions. The first portion of the tool comprises tubing, or a hollow shaft, at a length that gives the user adequate reach to the intended location. At one end of the tubing is the expanding hexagonal head fitting with six radial slits cut into it (one at each of the points of the hexagonal shape), and a small hole drilled axially through the center and the end opposite the hex is internally and externally threaded. This fitting is threaded into the shaft (via external threads) and staked or bonded so that it will not loosen. At the other end of the tubing is a knurled collar with a through hole into which the tubing is threaded. This knob is secured in place by a stop nut. The second assembled portion of the tool comprises a length of all thread or solid rod that is slightly longer than the steel tubing. One end has a slightly larger knurled collar affixed while the other end is tapered/pointed and threaded. When the two portions are assembled, the all thread/rod portion feeds through the tubing and is threaded into the expanding hex head fitting. The tapered point allows it to be driven into the through hole of the hex fitting. While holding the smaller collar on the shaft, the user turns the larger collar, and as the threads feed into the fitting, the hex head expands and grips the SHCS, thus providing a safe way to install and remove fasteners. The clamping force retaining the SHCS varies depending on how far the tapered end is inserted into the tool head. Initial tests of the prototype tool, designed for a 5 mm or # 10SHCS have resulted in up to 8 lb (.35.6 N) of pull force to dislodge the SHCS from the tool. The tool is designed with a lead-in angle from the diameter of the tubing to a diameter the same as the fastener head, to prevent the fastener head from catching on any obstructions encountered that could dislodge the fastener during retrieval.

  1. Diameter Control and Photoluminescence of ZnO Nanorods from Trialkylamines

    DOE PAGES

    Andelman, Tamar; Gong, Yinyan; Neumark, Gertrude; ...

    2007-01-01

    A novel solution method to control the diameter of ZnO nanorods is reported. Small diameter (2-3 nm) nanorods were synthesized from trihexylamine, and large diameter (50–80 nm) nanorods were synthesized by increasing the alkyl chain length to tridodecylamine. The defect (green) emission of the photoluminescence (PL) spectra of the nanorods varies with diameter, and can thus be controlled by the diameter control. The small ZnO nanorods have strong green emission, while the large diameter nanorods exhibit a remarkably suppressed green band. We show that this observation supports surface oxygen vacancies as the defect that gives rise to the green emission.

  2. [A case of hypothyroidism displaying "dropped head" syndrome].

    PubMed

    Furutani, Rikiya; Ishihara, Kenji; Miyazawa, Yumi; Suzuki, Yoshio; Shiota, Jun-Ichi; Kawamur, Mitsuru

    2007-01-01

    We describe a patient with hypothyroidism displaying "dropped head" syndrome. A 50-year-old man visited our clinic because he was unable to hold his head in the natural position. He had weakness and hypertrophy of the neck extensor muscles. Tendon reflexes were diminished or absent in all limbs. Mounding phenomena were observed in the bilateral upper extremities. Blood biochemical analysis revealed hypothyroidism, hyperlipidemia, and elevated levels of muscle-derived enzymes. Magnetic resonance imaging (MRI) of the neck demonstrated swelling and hyperintensity of the neck extensor muscles on T2-weighted images. The result of biopsy of the right biceps brachii muscle suggested mild atrophy of type 2 fibers. The diameters of the muscle fibers exhibited mild variation. No inflammatory changes were observed. We diagnosed hin as having "dropped head" syndrome due to hypothyroidism. Administration of thyroid hormone agent gradually improved his condition, and he became able to hold his head in the natural position. Levels of muscle-derived enzymes normalized and his hyperlipidemia remitted. Neck MRI also revealed improvement. Our findings suggest that hypothyroidism should be considered in the differential diagnosis of "dropped head" syndrome, although only a few cases like ours have been reported.

  3. Large tree diameter distribution modelling using sparse airborne laser scanning data in a subtropical forest in Nepal

    NASA Astrophysics Data System (ADS)

    Rana, Parvez; Vauhkonen, Jari; Junttila, Virpi; Hou, Zhengyang; Gautam, Basanta; Cawkwell, Fiona; Tokola, Timo

    2017-12-01

    Large-diameter trees (taking DBH > 30 cm to define large trees) dominate the dynamics, function and structure of a forest ecosystem. The aim here was to employ sparse airborne laser scanning (ALS) data with a mean point density of 0.8 m-2 and the non-parametric k-most similar neighbour (k-MSN) to predict tree diameter at breast height (DBH) distributions in a subtropical forest in southern Nepal. The specific objectives were: (1) to evaluate the accuracy of the large-tree fraction of the diameter distribution; and (2) to assess the effect of the number of training areas (sample size, n) on the accuracy of the predicted tree diameter distribution. Comparison of the predicted distributions with empirical ones indicated that the large tree diameter distribution can be derived in a mixed species forest with a RMSE% of 66% and a bias% of -1.33%. It was also feasible to downsize the sample size without losing the interpretability capacity of the model. For large-diameter trees, even a reduction of half of the training plots (n = 250), giving a marginal increase in the RMSE% (1.12-1.97%) was reported compared with the original training plots (n = 500). To be consistent with these outcomes, the sample areas should capture the entire range of spatial and feature variability in order to reduce the occurrence of error.

  4. Rotary drum separator system

    NASA Technical Reports Server (NTRS)

    Barone, Michael R. (Inventor); Murdoch, Karen (Inventor); Scull, Timothy D. (Inventor); Fort, James H. (Inventor)

    2009-01-01

    A rotary phase separator system generally includes a step-shaped rotary drum separator (RDS) and a motor assembly. The aspect ratio of the stepped drum minimizes power for both the accumulating and pumping functions. The accumulator section of the RDS has a relatively small diameter to minimize power losses within an axial length to define significant volume for accumulation. The pumping section of the RDS has a larger diameter to increase pumping head but has a shorter axial length to minimize power losses. The motor assembly drives the RDS at a low speed for separating and accumulating and a higher speed for pumping.

  5. Estradiol rapidly modulates spinogenesis in hippocampal dentate gyrus: Involvement of kinase networks.

    PubMed

    Hojo, Yasushi; Munetomo, Arisa; Mukai, Hideo; Ikeda, Muneki; Sato, Rei; Hatanaka, Yusuke; Murakami, Gen; Komatsuzaki, Yoshimasa; Kimoto, Tetsuya; Kawato, Suguru

    2015-08-01

    This article is part of a Special Issue "Estradiol and cognition". Estradiol (E2) is locally synthesized within the hippocampus and the gonads. Rapid modulation of hippocampal synaptic plasticity by E2 is essential for synaptic regulation. The molecular mechanisms of modulation through the synaptic estrogen receptor (ER) and its downstream signaling, however, are largely unknown in the dentate gyrus (DG). We investigated the E2-induced modulation of dendritic spines in male adult rat hippocampal slices by imaging Lucifer Yellow-injected DG granule cells. Treatments with 1 nM E2 increased the density of spines by approximately 1.4-fold within 2h. Spine head diameter analysis showed that the density of middle-head spines (0.4-0.5 μm) was significantly increased. The E2-induced spine density increase was suppressed by blocking Erk MAPK, PKA, PKC and LIMK. These suppressive effects by kinase inhibitors are not non-specific ones because the GSK-3β antagonist did not inhibit E2-induced spine increase. The ER antagonist ICI 182,780 also blocked the E2-induced spine increase. Taken together, these results suggest that E2 rapidly increases the density of spines through kinase networks that are driven by synaptic ER. Copyright © 2015 Elsevier Inc. All rights reserved.

  6. Echinostoma revolutum: Metacercariae in Filopaludina Snails from Nam Dinh Province, Vietnam, and Adults from Experimental Hamsters

    PubMed Central

    Chai, Jong-Yil; Na, Byoung-Kuk; Van De, Nguyen

    2011-01-01

    We detected metacercariae of Echinostoma revolutum in Filopaludina sp. snails purchased from a local market in Nam Dinh Province for the first time in Vietnam. Adult flukes were harvested from experimentally infected hamsters at days 14 and 17 post-infection. The metacercariae were round, 170-190 µm (n=15) in diameter, with a cyst wall thickness of about 12 µm. A total of 37 collar spines were arranged around the head collar, and large excretory granules were seen in 2 canals of the excretory bladder. The 14-day old adult flukes were elongated, ventrally curved, and 5.0-7.2×0.8-1.3 mm (n=20). The head collar had a total of 37 collar spines arranged in 2 alternating rows, including 5 corner spines on each side. The cirrus sac contained a saccular seminal vesicle, a prostatic gland, and an unarmed cirrus. Two tandem testes were smooth or slightly lobed. Eggs were ovoid to elliptical, 110-118×70-75 µm. These morphological characters were similar to those of E. revolutum and E. jurini. We tentatively identified it as E. revolutum because the validity of E. jurini remains to be elucidated. The taxonomic relationship of E. revolutum and E. jurini is discussed. PMID:22355218

  7. The Importance of Large-Diameter Trees to Forest Structural Heterogeneity

    PubMed Central

    Lutz, James A.; Larson, Andrew J.; Freund, James A.; Swanson, Mark E.; Bible, Kenneth J.

    2013-01-01

    Large-diameter trees dominate the structure, dynamics and function of many temperate and tropical forests. However, their attendant contributions to forest heterogeneity are rarely addressed. We established the Wind River Forest Dynamics Plot, a 25.6 ha permanent plot within which we tagged and mapped all 30,973 woody stems ≥1 cm dbh, all 1,966 snags ≥10 cm dbh, and all shrub patches ≥2 m2. Basal area of the 26 woody species was 62.18 m2/ha, of which 61.60 m2/ha was trees and 0.58 m2/ha was tall shrubs. Large-diameter trees (≥100 cm dbh) comprised 1.5% of stems, 31.8% of basal area, and 17.6% of the heterogeneity of basal area, with basal area dominated by Tsuga heterophylla and Pseudotsuga menziesii. Small-diameter subpopulations of Pseudotsuga menziesii, Tsuga heterophylla and Thuja plicata, as well as all tree species combined, exhibited significant aggregation relative to the null model of complete spatial randomness (CSR) up to 9 m (P≤0.001). Patterns of large-diameter trees were either not different from CSR (Tsuga heterophylla), or exhibited slight aggregation (Pseudotsuga menziesii and Thuja plicata). Significant spatial repulsion between large-diameter and small-diameter Tsuga heterophylla suggests that large-diameter Tsuga heterophylla function as organizers of tree demography over decadal timescales through competitive interactions. Comparison among two forest dynamics plots suggests that forest structural diversity responds to intermediate-scale environmental heterogeneity and disturbances, similar to hypotheses about patterns of species richness, and richness- ecosystem function. Large mapped plots with detailed within-plot environmental spatial covariates will be required to test these hypotheses. PMID:24376579

  8. The importance of large-diameter trees to forest structural heterogeneity.

    PubMed

    Lutz, James A; Larson, Andrew J; Freund, James A; Swanson, Mark E; Bible, Kenneth J

    2013-01-01

    Large-diameter trees dominate the structure, dynamics and function of many temperate and tropical forests. However, their attendant contributions to forest heterogeneity are rarely addressed. We established the Wind River Forest Dynamics Plot, a 25.6 ha permanent plot within which we tagged and mapped all 30,973 woody stems ≥ 1 cm dbh, all 1,966 snags ≥ 10 cm dbh, and all shrub patches ≥ 2 m(2). Basal area of the 26 woody species was 62.18 m(2)/ha, of which 61.60 m(2)/ha was trees and 0.58 m(2)/ha was tall shrubs. Large-diameter trees (≥ 100 cm dbh) comprised 1.5% of stems, 31.8% of basal area, and 17.6% of the heterogeneity of basal area, with basal area dominated by Tsuga heterophylla and Pseudotsuga menziesii. Small-diameter subpopulations of Pseudotsuga menziesii, Tsuga heterophylla and Thuja plicata, as well as all tree species combined, exhibited significant aggregation relative to the null model of complete spatial randomness (CSR) up to 9 m (P ≤ 0.001). Patterns of large-diameter trees were either not different from CSR (Tsuga heterophylla), or exhibited slight aggregation (Pseudotsuga menziesii and Thuja plicata). Significant spatial repulsion between large-diameter and small-diameter Tsuga heterophylla suggests that large-diameter Tsuga heterophylla function as organizers of tree demography over decadal timescales through competitive interactions. Comparison among two forest dynamics plots suggests that forest structural diversity responds to intermediate-scale environmental heterogeneity and disturbances, similar to hypotheses about patterns of species richness, and richness- ecosystem function. Large mapped plots with detailed within-plot environmental spatial covariates will be required to test these hypotheses.

  9. Effects of ageing on the hydraulics of water wells and the influence of non-Darcy flow

    NASA Astrophysics Data System (ADS)

    Houben, Georg J.; Wachenhausen, Julia; Guevara Morel, Carlos R.

    2018-04-01

    Well ageing is mostly caused by mechanical and biogeochemical clogging processes, which affect the gravel pack, screen slots and casing. Clogging deposits increase head losses due to a constriction of the hydraulically effective area. For this study, clogging is mimicked by systematically reducing the gravel pack porosity, the screen open area and the nominal inner casing diameter. Groundwater flow velocity strongly increases close to the well, inducing inertial and turbulent flow components. Therefore, gravel pack head losses were calculated using the Forchheimer-Engelund equation, in conjunction with the Kozeny-Carman equation, which relates gravel pack porosity and hydraulic conductivity. Screen losses were assessed using the Orifice equation and turbulent casing losses with the Darcy-Weisbach equation. For the settings chosen here, a dramatic increase of head losses occurs when the clogging has reduced the effective porosity in the gravel pack by 65%, the open area of the screen by ≥98%, and the casing diameter by 50%. Since the latter two conditions are rarely reached in actual wells, the clogging of the gravel pack is the decisive parameter that controls well ageing. Regular monitoring of the well yield is therefore needed, since processes in the gravel pack are difficult to track directly. Unlike the deposits on the casing and in the screen slots, obstructions in the gravel pack are much more difficult to remove.

  10. Effects of ageing on the hydraulics of water wells and the influence of non-Darcy flow

    NASA Astrophysics Data System (ADS)

    Houben, Georg J.; Wachenhausen, Julia; Guevara Morel, Carlos R.

    2018-06-01

    Well ageing is mostly caused by mechanical and biogeochemical clogging processes, which affect the gravel pack, screen slots and casing. Clogging deposits increase head losses due to a constriction of the hydraulically effective area. For this study, clogging is mimicked by systematically reducing the gravel pack porosity, the screen open area and the nominal inner casing diameter. Groundwater flow velocity strongly increases close to the well, inducing inertial and turbulent flow components. Therefore, gravel pack head losses were calculated using the Forchheimer-Engelund equation, in conjunction with the Kozeny-Carman equation, which relates gravel pack porosity and hydraulic conductivity. Screen losses were assessed using the Orifice equation and turbulent casing losses with the Darcy-Weisbach equation. For the settings chosen here, a dramatic increase of head losses occurs when the clogging has reduced the effective porosity in the gravel pack by 65%, the open area of the screen by ≥98%, and the casing diameter by 50%. Since the latter two conditions are rarely reached in actual wells, the clogging of the gravel pack is the decisive parameter that controls well ageing. Regular monitoring of the well yield is therefore needed, since processes in the gravel pack are difficult to track directly. Unlike the deposits on the casing and in the screen slots, obstructions in the gravel pack are much more difficult to remove.

  11. Isotachophoresis system having larger-diameter channels flowing into channels with reduced diameter and with selectable counter-flow

    DOEpatents

    Mariella, Jr., Raymond P.

    2018-03-06

    An isotachophoresis system for separating a sample containing particles into discrete packets including a flow channel, the flow channel having a large diameter section and a small diameter section; a negative electrode operably connected to the flow channel; a positive electrode operably connected to the flow channel; a leading carrier fluid in the flow channel; a trailing carrier fluid in the flow channel; and a control for separating the particles in the sample into discrete packets using the leading carrier fluid, the trailing carrier fluid, the large diameter section, and the small diameter section.

  12. Large-scale testing of in-vessel debris cooling through external flooding of the reactor pressure vessel in the CYBL facility

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chu, T.Y.; Bentz, J.H.; Bergeron, K.D.

    1994-04-01

    The possibility of achieving in-vessel core retention by flooding the reactor cavity, or the ``flooded cavity``, is an accident management concept currently under consideration for advanced light water reactors (ALWR), as well as for existing light water reactors (LWR). The CYBL (CYlindrical BoiLing) facility is a facility specifically designed to perform large-scale confirmatory testing of the flooded cavity concept. CYBL has a tank-within-a-tank design; the inner 3.7 m diameter tank simulates the reactor vessel, and the outer tank simulates the reactor cavity. The energy deposition on the bottom head is simulated with an array of radiant heaters. The array canmore » deliver a tailored heat flux distribution corresponding to that resulting from core melt convection. The present paper provides a detailed description of the capabilities of the facility, as well as results of recent experiments with heat flux in the range of interest to those required for in-vessel retention in typical ALWRs. The paper concludes with a discussion of other experiments for the flooded cavity applications.« less

  13. A full Monte Carlo simulation of the YAP-PEM prototype for breast tumor detection

    NASA Astrophysics Data System (ADS)

    Motta, A.; Righi, S.; Del Guerra, A.; Belcari, N.; Vaiano, A.; De Domenico, G.; Zavattini, G.; Campanini, R.; Lanconelli, N.; Riccardi, A.

    2004-07-01

    A prototype for Positron Emission Mammography, the YAP-PEM, is under development within a collaboration of the Italian Universities of Pisa, Ferrara, and Bologna. The aim is to detect breast lesions, with dimensions of 5 mm in diameter, and with a specific activity ratio of 10:1 between the cancer and breast tissue. The YAP-PEM is composed of two stationary detection heads of 6×6 cm 2, composed of a matrix of 30×30 YAP:Ce finger crystals of 2×2×30 mm 3 each. The EGSnrc Monte Carlo code has been used to simulate several characteristics of the prototype. A fast EM algorithm has been adapted to reconstruct all of the collected lines of flight, also at large incidence angles, by achieving 3D positioning capability of the lesion in the FOV. The role of the breast compression has been studied. The performed study shows that a 5 mm diameter tumor of 37 kBq/cm 3 (1 μCi/cm 3), embedded in active breast tissue with 10:1 tumor/background specific activity ratio, is detected in 10 min with a Signal-to-Noise Ratio of 8.7±1.0. Two hot lesions in the active breast phantom are clearly visible in the reconstructed image.

  14. Optoelectronic retinal prosthesis: system design and performance

    NASA Astrophysics Data System (ADS)

    Loudin, J. D.; Simanovskii, D. M.; Vijayraghavan, K.; Sramek, C. K.; Butterwick, A. F.; Huie, P.; McLean, G. Y.; Palanker, D. V.

    2007-03-01

    The design of high-resolution retinal prostheses presents many unique engineering and biological challenges. Ever smaller electrodes must inject enough charge to stimulate nerve cells, within electrochemically safe voltage limits. Stimulation sites should be placed within an electrode diameter from the target cells to prevent 'blurring' and minimize current. Signals must be delivered wirelessly from an external source to a large number of electrodes, and visual information should, ideally, maintain its natural link to eye movements. Finally, a good system must have a wide range of stimulation currents, external control of image processing and the option of either anodic-first or cathodic-first pulses. This paper discusses these challenges and presents solutions to them for a system based on a photodiode array implant. Video frames are processed and imaged onto the retinal implant by a head-mounted near-to-eye projection system operating at near-infrared wavelengths. Photodiodes convert light into pulsed electric current, with charge injection maximized by applying a common biphasic bias waveform. The resulting prosthesis will provide stimulation with a frame rate of up to 50 Hz in a central 10° visual field, with a full 30° field accessible via eye movements. Pixel sizes are scalable from 100 to 25 µm, corresponding to 640-10 000 pixels on an implant 3 mm in diameter.

  15. Analysis of pelvic rotation on the standard hip ventrodorsal extended radiographic view.

    PubMed

    Martins, João; Colaço, Bruno J; Ferreira, António J; Ginja, Mário M

    2016-01-01

    To study the symmetry of the iliac horizontal diameter (IHD) maximum obturator foramen width (OFW), ischiatic femoral overlap (IFO), pelvic horizontal radius (PHR), femoral head diameter (FHD), and obturator foramen area (OFA) parameters in the normal hip extended radiographic view and to evaluate the correlation of pelvic rotation with the magnitude of asymmetry of these parameters. Nine canine cadavers from adult, large and giant breeds were radiographed in standard hip extended views and with 2°, 4° and 6° degrees of rotation. The variables IHD, OFW, IFO, PHR, FHD, and OFA were analysed in radiographs. The IHD measurements exhibited repeatability, bilateral symmetry and 95% of confidence interval of asymmetry in different pelvic rotations without superposition (p <0.05); OFW and IFO exhibited repeatability, bilateral symmetry and a small superposition in 95% of confidence interval of asymmetry according different pelvic rotations; PHR, FHD and OFA exhibited repeatability, bilateral symmetry and unacceptable superposition in 95% of confidence interval of asymmetry depending on pelvic rotation. The IHD is the recommended variable and OFW is an acceptable variable in order to evaluate slight pelvic rotation. The data may be used in qualitative analyses of hip extended radiographic views. In the future, complementary studies should be performed to evaluate the impact of degree of pelvic rotation on the hip dysplasia score.

  16. Dose uniformity analysis among ten 16-slice same-model CT scanners.

    PubMed

    Erdi, Yusuf Emre

    2012-01-01

    With the introduction of multislice scanners, computed tomographic (CT) dose optimization has become important. The patient-absorbed dose may differ among the scanners although they are the same type and model. To investigate the dose output variation of the CT scanners, we designed the study to analyze dose outputs of 10 same-model CT scanners using 3 clinical protocols. Ten GE Lightspeed (GE Healthcare, Waukesha, Wis) 16-slice scanners located at main campus and various satellite locations of our institution have been included in this study. All dose measurements were performed using poly (methyl methacrylate) (PMMA) head (diameter, 16 cm) and body (diameter, 32 cm) phantoms manufactured by Radcal (RadCal Corp, Monrovia, Calif) using a 9095 multipurpose analyzer with 10 × 9-3CT ion chamber both from the same manufacturer. Ion chamber is inserted into the peripheral and central axis locations and volume CT dose index (CTDIvol) is calculated as weighted average of doses at those locations. Three clinical protocol settings for adult head, high-resolution chest, and adult abdomen are used for dose measurements. We have observed up to 9.4% CTDIvol variation for the adult head protocol in which the largest variation occurred among the protocols. However, head protocol uses higher milliampere second values than the other 2 protocols. Most of the measured values were less than the system-stored CTDIvol values. It is important to note that reduction in dose output from tubes as they age is expected in addition to the intrinsic radiation output fluctuations of the same scanner. Although the same model CT scanners were used in this study, it is possible to see CTDIvol variation in standard patient scanning protocols of head, chest, and abdomen. The compound effect of the dose variation may be larger with higher milliampere and multiphase and multilocation CT scans.

  17. Fundamental limits in heat-assisted magnetic recording and methods to overcome it with exchange spring structures

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Suess, D.; Abert, C.; Bruckner, F.

    2015-04-28

    The switching probability of magnetic elements for heat-assisted recording with pulsed laser heating was investigated. It was found that FePt elements with a diameter of 5 nm and a height of 10 nm show, at a field of 0.5 T, thermally written-in errors of 12%, which is significantly too large for bit-patterned magnetic recording. Thermally written-in errors can be decreased if larger-head fields are applied. However, larger fields lead to an increase in the fundamental thermal jitter. This leads to a dilemma between thermally written-in errors and fundamental thermal jitter. This dilemma can be partly relaxed by increasing the thickness of the FePtmore » film up to 30 nm. For realistic head fields, it is found that the fundamental thermal jitter is in the same order of magnitude of the fundamental thermal jitter in conventional recording, which is about 0.5–0.8 nm. Composite structures consisting of high Curie top layer and FePt as a hard magnetic storage layer can reduce the thermally written-in errors to be smaller than 10{sup −4} if the damping constant is increased in the soft layer. Large damping may be realized by doping with rare earth elements. Similar to single FePt grains in composite structure, an increase of switching probability is sacrificed by an increase of thermal jitter. Structures utilizing first-order phase transitions breaking the thermal jitter and writability dilemma are discussed.« less

  18. Covariation between human pelvis shape, stature, and head size alleviates the obstetric dilemma

    PubMed Central

    Fischer, Barbara; Mitteroecker, Philipp

    2015-01-01

    Compared with other primates, childbirth is remarkably difficult in humans because the head of a human neonate is large relative to the birth-relevant dimensions of the maternal pelvis. It seems puzzling that females have not evolved wider pelvises despite the high maternal mortality and morbidity risk connected to childbirth. Despite this seeming lack of change in average pelvic morphology, we show that humans have evolved a complex link between pelvis shape, stature, and head circumference that was not recognized before. The identified covariance patterns contribute to ameliorate the “obstetric dilemma.” Females with a large head, who are likely to give birth to neonates with a large head, possess birth canals that are shaped to better accommodate large-headed neonates. Short females with an increased risk of cephalopelvic mismatch possess a rounder inlet, which is beneficial for obstetrics. We suggest that these covariances have evolved by the strong correlational selection resulting from childbirth. Although males are not subject to obstetric selection, they also show part of these association patterns, indicating a genetic–developmental origin of integration. PMID:25902498

  19. Covariation between human pelvis shape, stature, and head size alleviates the obstetric dilemma.

    PubMed

    Fischer, Barbara; Mitteroecker, Philipp

    2015-05-05

    Compared with other primates, childbirth is remarkably difficult in humans because the head of a human neonate is large relative to the birth-relevant dimensions of the maternal pelvis. It seems puzzling that females have not evolved wider pelvises despite the high maternal mortality and morbidity risk connected to childbirth. Despite this seeming lack of change in average pelvic morphology, we show that humans have evolved a complex link between pelvis shape, stature, and head circumference that was not recognized before. The identified covariance patterns contribute to ameliorate the "obstetric dilemma." Females with a large head, who are likely to give birth to neonates with a large head, possess birth canals that are shaped to better accommodate large-headed neonates. Short females with an increased risk of cephalopelvic mismatch possess a rounder inlet, which is beneficial for obstetrics. We suggest that these covariances have evolved by the strong correlational selection resulting from childbirth. Although males are not subject to obstetric selection, they also show part of these association patterns, indicating a genetic-developmental origin of integration.

  20. Detection of Fatigue Cracks at Rivets with Self-Nulling Probe

    NASA Technical Reports Server (NTRS)

    Wincheski, Buzz; Fulton, Jim; Nath, Shridhar; Namkung, Min

    1994-01-01

    A new eddy current probe developed at NASA Langley Research Center has been used to detect small cracks at rivets in aircraft lap splices [1]. The device has earlier been used to detect isolated fatigue cracks with a minimum detectable flaw size of roughly 1/2 to 1/3 the diameter of the probe [2]. The present work shows that the detectable flaw size for cracks originating at rivets can be greatly improved upon from that of isolated flaws. The use of a rotating probe method combined with spatial filtering has been used to detect 0.18 cm EDM notches, as measured from the rivet shank, with a 1.27 cm diameter probe and to detect flaws buried under the rivet head, down to a length of 0.076 cm, using a 0.32 cm diameter probe. The Self-Nulling Electromagnetic Flaw Detector induces a high density eddy current ring in the sample under test. A ferromagnetic flux focusing lens is incorporated such that in the absence of any inhomogeneities in the material under test only a minimal magnetic field will reach the interior of the probe. A magnetometer (pickup coil) located in the center of the probe therefore registers a null voltage in the absence of material defects. When a fatigue crack or other discontinuity is present in the test article the path of the eddy currents in the material is changed. The magnetic field associated with these eddy currents then enter into the interior of the probe, producing a large output voltage across the pickup coil leads. Further

  1. The first perforating branch of the deep femoral artery: A reliable recipient vessel for vascularized fibular grafts: An anatomical study.

    PubMed

    Sur, Yoo Joon; Morsy, Mohamed; Mohan, Anita T; Zhu, Lin; Lachman, Nirusha; Saint-Cyr, Michel

    2016-03-01

    Although the perforating branches of the deep femoral artery have been introduced as recipient vessels for vascularized fibular grafts in the treatment of osteonecrosis of the femoral head, comprehensive knowledge of the related anatomy is deficient. The aims of this study were to provide detailed anatomical data for the perforating branches of the deep femoral artery and validate their usefulness as recipient vessels for vascularized fibular grafts. Anatomical dissection was performed on 11 fresh human cadaveric lower extremities. The number, locations, and diameters of the perforating branches were documented. The topographic relationships with the vastus ridge and the tendinous insertion of the gluteus maximus were clarified. The diameters of the perforating branches were compared with those of the ascending branch of the lateral circumflex femoral and the peroneal arteries. The mean number of perforating branches was 3.5. The mean distances from the vastus ridge to the first, second, and third perforating branches were 8.1, 13.7, and 20.4 cm, respectively. The first perforating branch was always located medial to the tendinous insertion of the gluteus maximus, whereas the second perforating branch was always located distal to the gluteus maximus. The mean diameters of the first, second, third, and fourth perforating branches were 3.1, 2.3, 1.6, and 1.2 mm, respectively. The mean diameters of the ascending branch of the lateral circumflex femoral and the peroneal arteries were 2.0 and 3.6 mm, respectively. The first perforating branch of the deep femoral artery is an appropriate alternative recipient vessel for vascularized fibular grafts in the treatment of osteonecrosis of the femoral head. It has a very consistent anatomy with a suitable location and diameter for anastomosis of the peroneal artery. Copyright © 2015 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

  2. Remotely Operated Vehicle ROV/AUV Reliability Study. Phase 2.

    DTIC Science & Technology

    1989-09-01

    produce workable configurations for large diameter cyl nders strong enough to survive high compression forces. 11 1.4.5.1.1 Composites Although FWE...Since the main cylinder in manned submersibles is typically large diameter , and the interior is only partially filled with equipment, these systems...ceramics involve control of tolerances when manufacturing large diameter cylinders, although ongoing R&D may provide solutions to this. The major

  3. Transient Temperature Analysis in a System of Thin Shells Combined with Convective and Radiative Cooling

    NASA Astrophysics Data System (ADS)

    Prasad, Ravindra; Samria, N. K.

    1989-01-01

    The problem considered has applications in the transient thermal analysis and time for attaining the steady state of the cylinder wall and cylinder head of an air-cooled internal-combustion engine. Numerical calculations based on finite difference approximations are carried out to assess the thermal response in a system of thin cylindrical and spherical shells having hot gases inside with convective boundary conditions. The outside surface is exposed to cooling medium where it looses heat by natural convection and radiation. As a special case, when radius is large, the surface may be considered to be a plane wall. The cylinder cover and cylinder wall of an internal-combustion engine are considered to be a plane wall for a comparatively higher ratio of cylinder diameter to the thickness of the wall, i.e., whend/δ varies from 80 to 100. A plot of temperature-time history and heat flow rates have been obtained.

  4. Implication of femoral stem on performance of articular surface replacement (ASR) XL total hip arthroplasty.

    PubMed

    Cip, Johannes; von Strempel, Archibald; Bach, Christian; Luegmair, Matthias; Benesch, Thomas; Martin, Arno

    2014-11-01

    Taper junctions of large diameter metal-on-metal femoral heads and femoral stems were described as metal ion generator due to accelerated wear and corrosion. However, literature about the Articular Surface Replacement (ASR) total hip arthroplasty (THA) invariably deals with stems manufactured by DePuy Orthopedics (Warsaw, IN, USA). Nothing is known whether different stems with common 12/14 mm tapers affect failure rate or ion release. 99 ASR THA (88 patients) implanted with CoxaFit or ARGE Geradschaft stems (K-Implant, Hannover, Germany) were retrospectively analyzed. After a mean follow-up of 3.5 years revision rate was 24.5%, mostly due to adverse reaction to metal debris (ARMD). CT scan revealed component loosening in 10.3% and pseudotumoral lesions in 12.6%. Elevated ion concentrations (>7 μg/l) were found in 38.6%. Copyright © 2014 Elsevier Inc. All rights reserved.

  5. Weak correlations between hemodynamic signals and ongoing neural activity during the resting state

    PubMed Central

    Winder, Aaron T.; Echagarruga, Christina; Zhang, Qingguang; Drew, Patrick J.

    2017-01-01

    Spontaneous fluctuations in hemodynamic signals in the absence of a task or overt stimulation are used to infer neural activity. We tested this coupling by simultaneously measuring neural activity and changes in cerebral blood volume (CBV) in the somatosensory cortex of awake, head-fixed mice during periods of true rest, and during whisker stimulation and volitional whisking. Here we show that neurovascular coupling was similar across states, and large spontaneous CBV changes in the absence of sensory input were driven by volitional whisker and body movements. Hemodynamic signals during periods of rest were weakly correlated with neural activity. Spontaneous fluctuations in CBV and vessel diameter persisted when local neural spiking and glutamatergic input was blocked, and during blockade of noradrenergic receptors, suggesting a non-neuronal origin for spontaneous CBV fluctuations. Spontaneous hemodynamic signals reflect a combination of behavior, local neural activity, and putatively non-neural processes. PMID:29184204

  6. Weak correlations between hemodynamic signals and ongoing neural activity during the resting state.

    PubMed

    Winder, Aaron T; Echagarruga, Christina; Zhang, Qingguang; Drew, Patrick J

    2017-12-01

    Spontaneous fluctuations in hemodynamic signals in the absence of a task or overt stimulation are used to infer neural activity. We tested this coupling by simultaneously measuring neural activity and changes in cerebral blood volume (CBV) in the somatosensory cortex of awake, head-fixed mice during periods of true rest and during whisker stimulation and volitional whisking. We found that neurovascular coupling was similar across states and that large, spontaneous CBV changes in the absence of sensory input were driven by volitional whisker and body movements. Hemodynamic signals during periods of rest were weakly correlated with neural activity. Spontaneous fluctuations in CBV and vessel diameter persisted when local neural spiking and glutamatergic input were blocked, as well as during blockade of noradrenergic receptors, suggesting a non-neuronal origin for spontaneous CBV fluctuations. Spontaneous hemodynamic signals reflect a combination of behavior, local neural activity, and putatively non-neural processes.

  7. Fractures of a single design of highly cross-linked polyethylene acetabular liners: an analysis of voluntary reports to the United States Food and Drug Administration.

    PubMed

    Ast, Michael P; John, Thomas K; Labbisiere, Anthony; Robador, Nicolas; Valle, Alejandro Gonzalez Della

    2014-06-01

    Polyethylene liner fracture is a risk associated with the use of highly cross-linked UHMWPE. We performed a review of the voluntary reports of fractured liners to the US Food and Drug Administration to determine if any risk factors could be identified. There have been 74 reports of fractured Trilogy, Longevity liners to the US Food and Drug Administration since 1999. Most cases utilized small acetabular shells (≤54 mm) combined with large diameter heads (≥36 mm). Liners less than 7 mm thick at the weight bearing or 4.8 mm thick at the rim should be used with caution. At revision surgery, malpositioned shells should be revised and the use of a thin liner should be avoided. Copyright © 2014 Elsevier Inc. All rights reserved.

  8. Numerical simulation of transient hypervelocity flow in an expansion tube

    NASA Technical Reports Server (NTRS)

    Jacobs, P. A.

    1992-01-01

    Several numerical simulations of the transient flow of helium in an expansion tube are presented in an effort to identify some of the basic mechanisms which cause the noisy test flows seen in experiments. The calculations were performed with an axisymmetric Navier-Stokes code based on a finite volume formulation and upwinding techniques. Although laminar flow and ideal bursting of the diaphragms was assumed, the simulations showed some of the important features seen in experiments. In particular, the discontinuity in tube diameter of the primary diaphragm station introduced a transverse perturbation to the expanding driver gas and this perturbation was seen to propagate into the test gas under some flow conditions. The disturbances seen in the test flow can be characterized as either small amplitude, low frequency noise possibly introduced during shock compression or large amplitude, high frequency noise associated with the passage of the reflected head of the unsteady expansion.

  9. Numerical simulation of transient hypervelocity flow in an expansion tube

    NASA Technical Reports Server (NTRS)

    Jacobs, P. A.

    1992-01-01

    Several numerical simulations of the transient flow of helium in an expansion tube are presented. The aim of the exercise is to provide further information on the operational problems of the NASA Langley expansion tube. The calculations were performed with an axisymmetric Navier-Stokes code based on a finite-volume formulation and upwinding techniques. Although laminar flow and ideal bursting of the diaphragms was assumed, the simulations showed some of the important features seen in the experiments. In particular, the discontinuity in the tube diameter at the primary diaphragm station introduced a transverse perturbation to the expanding driver gas, and this perturbation was seen to propagate into the test gas under some flow conditions. The disturbances seen in the test flow can be characterized as either 'small-amplitude' noise possibly introduced during shock compression or 'large-amplitude' noise associated with the passage of the reflected head of the unsteady expansion.

  10. Mechanics of water pore formation in lipid membrane under electric field

    NASA Astrophysics Data System (ADS)

    Bu, Bing; Li, Dechang; Diao, Jiajie; Ji, Baohua

    2017-04-01

    Transmembrane water pores are crucial for substance transport through cell membranes via membrane fusion, such as in neural communication. However, the molecular mechanism of water pore formation is not clear. In this study, we apply all-atom molecular dynamics and bias-exchange metadynamics simulations to study the process of water pore formation under an electric field. We show that water molecules can enter a membrane under an electric field and form a water pore of a few nanometers in diameter. These water molecules disturb the interactions between lipid head groups and the ordered arrangement of lipids. Following the movement of water molecules, the lipid head groups are rotated and driven into the hydrophobic region of the membrane. The reorientated lipid head groups inside the membrane form a hydrophilic surface of the water pore. This study reveals the atomic details of how an electric field influences the movement of water molecules and lipid head groups, resulting in water pore formation.

  11. Electric arc welding gun

    DOEpatents

    Luttrell, Edward; Turner, Paul W.

    1978-01-01

    This invention relates to improved apparatus for arc welding an interior joint formed by intersecting tubular members. As an example, the invention is well suited for applications where many similar small-diameter vertical lines are to be welded to a long horizontal header. The improved apparatus includes an arc welding gun having a specially designed welding head which is not only very compact but also produces welds that are essentially free from rolled-over solidified metal. The welding head consists of the upper end of the barrel and a reversely extending electrode holder, or tip, which defines an acute angle with the barrel. As used in the above-mentioned example, the gun is positioned to extend upwardly through the vertical member and the joint to be welded, with its welding head disposed within the horizontal header. Depending on the design of the welding head, the barrel then is either rotated or revolved about the axis of the vertical member to cause the electrode to track the joint.

  12. Numerical analysis of specific absorption rate in the human head due to a 13.56 MHz RFID-based intra-ocular pressure measurement system.

    PubMed

    Hirtl, Rene; Schmid, Gernot

    2013-09-21

    A modern wireless intra-ocular pressure monitoring system, based on 13.56 MHz inductively coupled data transmission, was dosimetrically analyzed with respect to the specific absorption rate (SAR) induced inside the head and the eye due to the electromagnetic field exposure caused by the reader antenna of the transmission system. The analysis was based on numerical finite difference time domain computations using a high resolution anatomical eye model integrated in a modern commercially available anatomical model of a male head. Three different reader antenna configurations, a 7-turn elliptic (30 mm × 50 mm) antenna at 12 mm distance from the eye, a flexible circular antenna (60 mm diameter, 8 turns on 2 mm substrate) directly attached to the skin, and a circular 7-turn antenna (30 mm diameter at 12 mm distance to the eye) were analyzed, respectively. Possible influences of the eye-lid status (closed or opened) and the transponder antenna contained in a contact lens directly attached to the eye were taken into account. The results clearly demonstrated that for typical reader antenna currents required for proper data transmission, the SAR values remain far below the limits for localized exposure of the head, as defined by the International Commission for Non-Ionizing Radiation Protection. Particularly the induced SAR inside the eye was found to be substantially (orders of magnitudes for typical reader antenna currents in the order of 1 A turn) below values which have been reported to be critical with respect to thermally induced adverse health effects in eye tissues.

  13. A cutting-edge solution for 1µm laser metal processing

    NASA Astrophysics Data System (ADS)

    Baumbach, N.; Kühl, P.; Karam, J.; Jonkers, J.; Villarreal-Saucedo, F.; Reyes, M.

    2017-02-01

    The recent 1μm-laser cutting market is dominated by fiber and disk lasers due to their excellent beam quality of below 4mm*mrad. Teradiode's 4kW direct diode laser source achieves similar beam quality while having a different beam shape and shorter wavelengths which are known for higher absorption rates at the inclined front of the cutting keyhole. Research projects, such as the HALO Project, have additionally shown that polarized radiation and beams with shapes different from the typical LG00 lead to improved cut quality for ferrous and non-ferrous metals. [1] Diode laser have the inherent property of not being sensitive to back reflection which brings advantages in cutting high-reflective materials. The II-VI HIGHYAG laser cutting head BIMO-FSC offers the unique feature of machine controlled and continuous adjustment of both the focus diameter and the focus position. This feature is proven to be beneficial for cutting and piercing with high speed and small hole diameters. In addition, the optics are designed for lowest focus shift. As a leading laser processing head manufacturer, II-VI HIGHYAG qualified its BIMO-FSC MZ (M=magnification, Z=focus position) cutting head for Teradiode's 4kW direct diode laser source to offer a cutting-edge solution for highpower laser cutting. Combining the magnification ability of the cutting head with this laser source, customers experience strong advantages in cutting metals in broad thickness ranges. Thicknesses up to 25mm mild steel can easily be cut with excellent edge quality. Furthermore, a new optical setup equivalent to an axicon with a variable axicon angle is demonstrated which generates variable sized ring spots. The setup provides new degrees of freedom to tailor the energy distribution for even higher productivity and quality.

  14. Management of non-traumatic avascular necrosis of the femoral head-a comparative analysis of the outcome of multiple small diameter drilling and core decompression with fibular grafting.

    PubMed

    Mohanty, S P; Singh, K A; Kundangar, R; Shankar, V

    2017-04-01

    The purpose of this study was to compare the clinical and radiological outcomes of multiple small diameter drilling and core decompression with fibular strut grafting in the management of non-traumatic avascular necrosis (AVN) of the femoral head. Outcomes of patients with AVN treated by multiple small diameter drilling (group 1) were compared retrospectively with patients treated by core decompression and fibular grafting (group 2). Harris hip score (HHS) was used to assess the clinical status pre- and postoperatively. Modified Ficat and Arlet classification was used to assess the radiological stage pre- and postoperatively. Forty-six patients (68 hips) were included in this study. Group 1 consisted of 33 hips, and group 2 consisted of 35 hips. In stages I and IIB, there was no statistically significant difference in the final HHS between the two groups. However, in stages IIA and III, hips in group 2 had a better final HHS (P < 0.05). In terms of radiographic progression, there was no statistical difference between hips in stages I, IIA and stage IIB. However, in stage III, hips belonging to group 2 had better results (P < 0.05). Kaplan-Meier survivorship analysis showed better outcome in group 2 in stage III (P < 0.05). Hips with AVN in the precollapse stage can be salvaged by core decompression with or without fibular grafting. Multiple small diameter drilling is relatively simple and carries less morbidity and hence preferred in stages I and II. However, in stage III disease, core decompression with fibular strut grafting gives better results.

  15. In situ observation of lubricant film formation in THR considering real conformity: The effect of diameter, clearance and material.

    PubMed

    Nečas, D; Vrbka, M; Urban, F; Gallo, J; Křupka, I; Hartl, M

    2017-05-01

    The aim of the present study is to provide an analysis of protein film formation in hip joint replacements considering real conformity based on in situ observation of the contact zone. The main attention is focused on the effect of implant nominal diameter, diametric clearance and material. For this purpose, a pendulum hip joint simulator equipped with electromagnetic motors enabling to apply continuous swinging flexion-extension motion was employed. The experimental configuration consists of femoral component (CoCrMo, BIOLOX®forte, BIOLOX®delta) and acetabular cup from optical glass fabricated according to the dimensions of real cups. Two nominal diameters were studied, 28 and 36mm, respectively, while different diametric clearances were considered. Initially, a static test focused on the protein adsorption onto rubbing surfaces was performed with 36mm implants. It was found that the development of adsorbed layer is much more stable in the case of metal head, indicating that the adsorption forces are stronger compared to ceramic. A consequential swinging test revealed that the fundamental parameter influencing the protein film formation is diametric clearance. Independently of implant diameter, film was much thicker when a smaller clearance was considered. An increase of implant size from 28mm to 36mm did not cause a substantial difference in film formation; however, the total film thickness was higher for smaller implant. In terms of material, metal heads formed a thicker film, while this fact can be, among others, also attributed to clearance, which is more than two times higher in the case of ceramic implant. Copyright © 2016 Elsevier Ltd. All rights reserved.

  16. [The sural medial perforator flap: Anatomical bases, surgical technique and indications in head and neck reconstruction].

    PubMed

    Struk, S; Schaff, J-B; Qassemyar, Q

    2018-04-01

    The medial sural artery perforator (MSAP) flap is defined as a thin cutaneo-adipose perforator flap harvested on the medial aspect of the leg. The aims of this study were to describe the anatomical basis as well as the surgical technique and discuss the indications in head and neck reconstructive surgery. We harvested 10 MSAP flap on 5 fresh cadavers. For each case, the number and the location of the perforators were recorded. For each flap, the length of pedicle, the diameter of source vessels and the thickness of the flap were studied. Finally, we performed a clinical application of a MSAP flap. A total of 23 perforators with a diameter superior than 1mm were dissected on 10 legs. The medial sural artery provided between 1 and 4 musculocutaneous perforators. Perforators were located in average at 10.3cm±2cm from the popliteal fossa and at 3.6cm±1cm from the median line of the calf. The mean pedicle length was 12.1cm±2.5cm. At its origin, the source artery diameter was 1.8mm±0.25mm and source veins diameters were 2.45mm±0.9mm in average. There was no complication in our clinical application. This study confirms the reliability of previous anatomical descriptions of the medial sural artery perforator flap. This flap was reported as thin and particularly adapted for oral cavity reconstruction and for facial or limb resurfacing. Sequelae might be reduced as compared to those of the radial forearm flap with comparable results. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  17. Development of a dual-energy computed tomography quality control program: Characterization of scanner response and definition of relevant parameters for a fast-kVp switching dual-energy computed tomography system.

    PubMed

    Nute, Jessica L; Jacobsen, Megan C; Stefan, Wolfgang; Wei, Wei; Cody, Dianna D

    2018-04-01

    A prototype QC phantom system and analysis process were developed to characterize the spectral capabilities of a fast kV-switching dual-energy computed tomography (DECT) scanner. This work addresses the current lack of quantitative oversight for this technology, with the goal of identifying relevant scan parameters and test metrics instrumental to the development of a dual-energy quality control (DEQC). A prototype elliptical phantom (effective diameter: 35 cm) was designed with multiple material inserts for DECT imaging. Inserts included tissue equivalent and material rods (including iodine and calcium at varying concentrations). The phantom was scanned on a fast kV-switching DECT system using 16 dual-energy acquisitions (CTDIvol range: 10.3-62 mGy) with varying pitch, rotation time, and tube current. The circular head phantom (22 cm diameter) was scanned using a similar protocol (12 acquisitions; CTDIvol range: 36.7-132.6 mGy). All acquisitions were reconstructed at 50, 70, 110, and 140 keV and using a water-iodine material basis pair. The images were evaluated for iodine quantification accuracy, stability of monoenergetic reconstruction CT number, noise, and positional constancy. Variance component analysis was used to identify technique parameters that drove deviations in test metrics. Variances were compared to thresholds derived from manufacturer tolerances to determine technique parameters that had a nominally significant effect on test metrics. Iodine quantification error was largely unaffected by any of the technique parameters investigated. Monoenergetic HU stability was found to be affected by mAs, with a threshold under which spectral separation was unsuccessful, diminishing the utility of DECT imaging. Noise was found to be affected by CTDIvol in the DEQC body phantom, and CTDIvol and mA in the DEQC head phantom. Positional constancy was found to be affected by mAs in the DEQC body phantom and mA in the DEQC head phantom. A streamlined scan protocol was developed to further investigate the effects of CTDIvol and rotation time while limiting data collection to the DEQC body phantom. Further data collection will be pursued to determine baseline values and statistically based failure thresholds for the validation of long-term DECT scanner performance. © 2018 American Association of Physicists in Medicine.

  18. 77 FR 6772 - United States Standards for Grades of Cauliflower

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-09

    ... provisions for grading purple, orange or green cauliflower. The proposed revision will amend the color requirement for curds to allow all colors of cauliflower to be certified to a U.S. grade. In addition, AMS proposes to permit mixed color packs, heads less than 4 inches in diameter, and to remove the unclassified...

  19. DEVELOPMENT OF THE CONCEPT OF THE BIMODAL DISTRIBUTION OF PARTICLES: A PERSONAL HISTORY

    EPA Science Inventory

    The author was hired by EPA in 1971 to head the new Aerosol Research Section (ARS), the first EPA unit devoted to research on atmospheric aerosols. At that time the existing paradigm was that the atmospheric aerosol distribution was monomodal , the mass mean diameter was one mic...

  20. An aerodynamic investigation of two 1.83-meter-diameter fan systems designed to drive a subsonic wind tunnel

    NASA Technical Reports Server (NTRS)

    Page, V. R.; Eckert, W. T.; Mort, K. W.

    1977-01-01

    An experimental, aerodynamic investigation was made of two 1.83 m diameter fan systems which are being considered for the repowered drive section of the 40- by 80-foot wind tunnel at NASA Ames Research Center. One system was low speed, the other was high speed. The low speed fan was tested at various stagger angles from 32.9 deg to 62.9 deg. At a fan blade stagger angle of 40.8 deg and operating at a tip speed of 1155 m/sec, the low speed fan developed 207.3 m of head. The high speed fan had a design blade stagger angle of 56.2 deg and was tested at this stagger angle only. The high speed fan operating at 191.5 m/sec developed 207.3 m of head. Radial distributions of static pressure coefficients, total pressure coefficients, and angles of swirl are presented. Radial surveys were conducted at four azimuth locations in front of the fan, and repeated downstream of the fan. Data were taken for various flow control devices and for two inlet contraction lengths.

  1. ARC-1980-A80-7034

    NASA Image and Video Library

    1980-11-12

    Range : 660,000 kilometers (400,000 miles) Time : 5:05 am PST This Voyager 1 picture of Mimas shows a large impact structure at 110 degrees W Long., located on that face of the moon which leads Mimas in its orbit. The feature, about 130 kilometers in diameter (80 miles), is more than 1/4 the diameter of the entire moon. This is a particularly interesting feature in view of its large diameter compared with the size of the satellite, and may have the largest crater diameter/satillite diameter ratio in the solar system. The crater has a raised rim and central peak, typical of large impact structures on terrestrial planets. Additional smaller craters, 15-45 kilometers in diameter, can be seen scattered across the surface, particularly alon the terminator. Mimas is one of the smaller Saturnian satellites with a low density implying its chief component is ice.

  2. PHYSICAL PROPERTIES OF LARGE AND SMALL GRANULES IN SOLAR QUIET REGIONS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yu Daren; Xie Zongxia; Hu Qinghua

    The normal mode observations of seven quiet regions obtained by the Hinode spacecraft are analyzed to study the physical properties of granules. An artificial intelligence technique is introduced to automatically find the spatial distribution of granules in feature spaces. In this work, we investigate the dependence of granular continuum intensity, mean Doppler velocity, and magnetic fields on granular diameter. We recognized 71,538 granules by an automatic segmentation technique and then extracted five properties: diameter, continuum intensity, Doppler velocity, and longitudinal and transverse magnetic flux density to describe the granules. To automatically explore the intrinsic structures of the granules in themore » five-dimensional parameter space, the X-means clustering algorithm and one-rule classifier are introduced to define the rules for classifying the granules. It is found that diameter is a dominating parameter in classifying the granules and two families of granules are derived: small granules with diameters smaller than 1.''44, and large granules with diameters larger than 1.''44. Based on statistical analysis of the detected granules, the following results are derived: (1) the averages of diameter, continuum intensity, and Doppler velocity in the upward direction of large granules are larger than those of small granules; (2) the averages of absolute longitudinal, transverse, and unsigned flux density of large granules are smaller than those of small granules; (3) for small granules, the average of continuum intensity increases with their diameters, while the averages of Doppler velocity, transverse, absolute longitudinal, and unsigned magnetic flux density decrease with their diameters. However, the mean properties of large granules are stable; (4) the intensity distributions of all granules and small granules do not satisfy Gaussian distribution, while that of large granules almost agrees with normal distribution with a peak at 1.04 I{sub 0}.« less

  3. 78 FR 60897 - Certain Welded Large Diameter Line Pipe From Japan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ... Diameter Line Pipe From Japan Determination On the basis of the record \\1\\ developed in the subject five... order on certain welded large diameter line pipe from Japan would likely to lead to continuation or... Line Pipe from Japan: Investigation No. 731-TA-919 (Second Review). By order of the Commission. Issued...

  4. Diagnostic accuracy of maternal anthropometric measurements as predictors for dystocia in nulliparous women

    PubMed Central

    Alijahan, Rahele; Kordi, Masoumeh; Poorjavad, Munira; Ebrahimzadeh, Saeed

    2014-01-01

    Background: Dystocia is one of the important causes of maternal morbidity and mortality in low-income countries. This study was aimed to determine the diagnostic accuracy of maternal anthropometric measurements as predictors for dystocia in nulliparous women. Materials and Methods: This prospective cohort study was conducted on 447 nulliparous women who referred to Omolbanin hospital. Several maternal anthropometric measurements such as height, transverse and vertical diameters of Michaelis sacral rhomboid area, foot length, head circumference, vertebral and lower limb length, symphysio-fundal height, and abdominal girth were taken in cervical dilatation ≤ 5 cm. Labor progression was controlled by a researcher blind to these measurements. After delivery, the accuracy of individual and combined measurements in prediction of dystocia was analyzed. Dystocia was defined as cesarean section and vacuum or forceps delivery for abnormal progress of labor (cervical dilatation less than 1 cm/h in the active phase for 2 h, and during the second stage, beyond 2 h or fetal head descend less than 1 cm/h). Results: Among the different anthropometric measurements, transverse diameter of the Michaelis sacral rhomboid area ≤9.6 cm, maternal height ≤ 155 cm, height to symphysio-fundal height ratio ≤4.7, lower limb length ≤78 cm, and head circumference to height ratio ≥ 35.05 with accuracy of 81.2%, 68.2%, 65.5%, 63.3%, and 61.5%, respectively, were better predictors. The best predictor was obtained by combination of maternal height ≤155 cm or the transverse diameter of the Michaelis sacral rhomboid area ≤9.6 cm and Johnson's formula estimated fetal weight ≥3255 g, with an accuracy of 90.5%, sensitivity of 70%, and specificity of 93.7%. Conclusions: Combination of other anthropometric measurements and estimated fetal weight with maternal height in comparison to maternal height alone leads to a better predictor for dystocia. PMID:24554954

  5. Diagnostic accuracy of maternal anthropometric measurements as predictors for dystocia in nulliparous women.

    PubMed

    Alijahan, Rahele; Kordi, Masoumeh; Poorjavad, Munira; Ebrahimzadeh, Saeed

    2014-01-01

    Dystocia is one of the important causes of maternal morbidity and mortality in low-income countries. This study was aimed to determine the diagnostic accuracy of maternal anthropometric measurements as predictors for dystocia in nulliparous women. This prospective cohort study was conducted on 447 nulliparous women who referred to Omolbanin hospital. Several maternal anthropometric measurements such as height, transverse and vertical diameters of Michaelis sacral rhomboid area, foot length, head circumference, vertebral and lower limb length, symphysio-fundal height, and abdominal girth were taken in cervical dilatation ≤ 5 cm. Labor progression was controlled by a researcher blind to these measurements. After delivery, the accuracy of individual and combined measurements in prediction of dystocia was analyzed. Dystocia was defined as cesarean section and vacuum or forceps delivery for abnormal progress of labor (cervical dilatation less than 1 cm/h in the active phase for 2 h, and during the second stage, beyond 2 h or fetal head descend less than 1 cm/h). Among the different anthropometric measurements, transverse diameter of the Michaelis sacral rhomboid area ≤9.6 cm, maternal height ≤ 155 cm, height to symphysio-fundal height ratio ≤4.7, lower limb length ≤78 cm, and head circumference to height ratio ≥ 35.05 with accuracy of 81.2%, 68.2%, 65.5%, 63.3%, and 61.5%, respectively, were better predictors. The best predictor was obtained by combination of maternal height ≤155 cm or the transverse diameter of the Michaelis sacral rhomboid area ≤9.6 cm and Johnson's formula estimated fetal weight ≥3255 g, with an accuracy of 90.5%, sensitivity of 70%, and specificity of 93.7%. Combination of other anthropometric measurements and estimated fetal weight with maternal height in comparison to maternal height alone leads to a better predictor for dystocia.

  6. SU-G-TeP1-08: LINAC Head Geometry Modeling for Cyber Knife System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liang, B; Li, Y; Liu, B

    Purpose: Knowledge of the LINAC head information is critical for model based dose calculation algorithms. However, the geometries are difficult to measure precisely. The purpose of this study is to develop linac head models for Cyber Knife system (CKS). Methods: For CKS, the commissioning data were measured in water at 800mm SAD. The measured full width at half maximum (FWHM) for each cone was found greater than the nominal value, this was further confirmed by additional film measurement in air. Diameter correction, cone shift and source shift models (DCM, CSM and SSM) are proposed to account for the differences. Inmore » DCM, a cone-specific correction is applied. For CSM and SSM, a single shift is applied to the cone or source physical position. All three models were validated with an in-house developed pencil beam dose calculation algorithm, and further evaluated by the collimator scatter factor (Sc) correction. Results: The mean square error (MSE) between nominal diameter and the FWHM derived from commissioning data and in-air measurement are 0.54mm and 0.44mm, with the discrepancy increasing with cone size. Optimal shift for CSM and SSM is found to be 9mm upward and 18mm downward, respectively. The MSE in FWHM is reduced to 0.04mm and 0.14mm for DCM and CSM (SSM). Both DCM and CSM result in the same set of Sc values. Combining all cones at SAD 600–1000mm, the average deviation from 1 in Sc of DCM (CSM) and SSM is 2.6% and 2.2%, and reduced to 0.9% and 0.7% for the cones with diameter greater than 15mm. Conclusion: We developed three geometrical models for CKS. All models can handle the discrepancy between vendor specifications and commissioning data. And SSM has the best performance for Sc correction. The study also validated that a point source can be used in CKS dose calculation algorithms.« less

  7. Simulation of Sub-Drains Performance Using Visual MODFLOW for Slope Water Seepage Problem

    NASA Astrophysics Data System (ADS)

    Baharuddin, M. F. T.; Tajudin, S. A. A.; Abidin, M. H. Z.; Yusoff, N. A.

    2016-07-01

    Numerical simulation technique was used for investigating water seepage problem at the Botanic Park Kuala Lumpur. A proposed sub-drains installation in problematic site location was simulated using Modular Three-Dimensional Finite Difference Groundwater Flow (MODFLOW) software. The results of simulation heads during transient condition showed that heads in between 43 m (water seepage occurred at level 2) until 45 m (water seepage occurred at level 4) which heads measurement are referred to mean sea level. However, elevations measurements for level 2 showed the values between 41 to 42 m from mean sea level and elevations for level 4 between 42 to 45 m from mean sea level. These results indicated an increase in heads for level 2 and level 4 between 1 to 2 m when compared to elevations slope at the level 2 and level 4. The head increases surpass the elevation level of the slope area that causing water seepage at level 2 and level 4. In order to overcome this problems, the heads level need to be decrease to 1 until 2 m by using two options of sub-drain dimension size. Sub-drain with the dimension of 0.0750 m (diameter), 0.10 m (length) and using 4.90 m spacing was the best method to use as it was able to decrease the heads to the required levels of 1 to 2 m.

  8. Verification of the FBR fuel bundle-duct interaction analysis code BAMBOO by the out-of-pile bundle compression test with large diameter pins

    NASA Astrophysics Data System (ADS)

    Uwaba, Tomoyuki; Ito, Masahiro; Nemoto, Junichi; Ichikawa, Shoichi; Katsuyama, Kozo

    2014-09-01

    The BAMBOO computer code was verified by results for the out-of-pile bundle compression test with large diameter pin bundle deformation under the bundle-duct interaction (BDI) condition. The pin diameters of the examined test bundles were 8.5 mm and 10.4 mm, which are targeted as preliminary fuel pin diameters for the upgraded core of the prototype fast breeder reactor (FBR) and for demonstration and commercial FBRs studied in the FaCT project. In the bundle compression test, bundle cross-sectional views were obtained from X-ray computer tomography (CT) images and local parameters of bundle deformation such as pin-to-duct and pin-to-pin clearances were measured by CT image analyses. In the verification, calculation results of bundle deformation obtained by the BAMBOO code analyses were compared with the experimental results from the CT image analyses. The comparison showed that the BAMBOO code reasonably predicts deformation of large diameter pin bundles under the BDI condition by assuming that pin bowing and cladding oval distortion are the major deformation mechanisms, the same as in the case of small diameter pin bundles. In addition, the BAMBOO analysis results confirmed that cladding oval distortion effectively suppresses BDI in large diameter pin bundles as well as in small diameter pin bundles.

  9. Fracture resistance and reliability of new zirconia posts.

    PubMed

    Oblak, Cedomir; Jevnikar, Peter; Kosmac, Tomaz; Funduk, Nenad; Marion, Ljubo

    2004-04-01

    The radicular portion of zirconia endodontic posts often need to be reshaped to achieve a definitive form and may be airborne-particle abraded to improve adhesion during luting. Therefore, the surface of the tetragonal zirconia ceramics may be transformed and damaged, influencing the mechanical properties of the material. This study compared the fracture resistance of prefabricated zirconia posts with a new retentive post-head after different surface treatments. Experimental zirconia posts of 2 different diameters, 1.3 mm and 1.5 mm, were produced from commercially available zirconia powder. A cylindro-conical outline form was used for the root portion of the system and a post-head with 3 retentive rings was designed. Sixty posts of each diameter were divided into 3 groups (n=20). Group 1 was ground with a coarse grit diamond bur; Group 2 was airborne-particle abraded with 110-microm fused alumina particles, and Group 3 was left as-received (controls). Posts were luted into the root-shaped artificial canals with the Clearfil adhesive system and Panavia 21 adhesive resin luting agent. The posts were loaded in a universal testing machine at an inclination of 45 degrees with the constant cross-head speed of 1 mm/min. The fracture load (N) necessary to cause post fracture was recorded, and the statistical significance of differences among groups was analyzed with 1-way ANOVA followed by the Fischer LSD test (alpha=.05). The variability was analyzed using Weibull statistics. Load to fracture values of all zirconia posts depended primarily on post diameter. Mean fracture loads (SD) in Newtons were 518.4 (+/-101.3), 993.6 (+/-224.1), and 622.7 (+/-110.3) for Groups 1 through 3, respectively, for thicker posts, and 385.9 (+/-110.3), 627.0 (+/-115.1), and 451.2 (+/-81.4) for Groups 1 through 3, respectively, for thinner posts. Airborne-particle-abraded posts exhibited significantly higher resistance to fracture (P<.05) than those in the other 2 groups for diameters 1.3 mm and 1.5 mm. Grinding reduced Weibull modulus compared with controls, and the values were 4.1 and 6.5 for thicker and thinner posts, respectively. Within the limitations of this study, the results suggest that grinding leads to a significant drop in load to fracture of zirconia posts, whereas airborne-particle abrasion increased the fracture load.

  10. Modified duval procedure for small-duct chronic pancreatitis without head dominance.

    PubMed

    Oida, Takatsugu; Aramaki, Osamu; Kano, Hisao; Mimatsu, Kenji; Kawasaki, Atsushi; Kuboi, Youichi; Fukino, Nobutada; Kida, Kazutoshi; Amano, Sadao

    2011-01-01

    In the case of small-duct chronic pancreatitis, surgery for pain relief is broadly divided into resection and drainage procedures. These procedures should be selected according to the location of dominant lesion, diameter of the pancreatic duct and extent of the disease. The appropriate procedure for the treatment of small-duct chronic pancreatitis, especially small-duct chronic pancreatitis without head dominance, remains controversial. We developed the modified Duval procedure for the treatment of small-duct chronic pancreatitis without head dominance and determined the efficacy of this procedure. We retrospectively studied 14 patients who underwent surgical drainage with or without pancreatic resection for chronic pancreatitis with small pancreatic duct (<7mm) without head dominance. These patients were divided into 2 groups; the modified Puestow procedure group and the modified Duval procedure group. No complications occurred in the modified Duval group. In the modified Puestow procedure group, complete and partial pain relief were observed in 62.5%, and 37.5% of patients respectively. In contrast, complete pain relief was observed in all the patients in the modified Duval procedure group. Our modified Duval procedure is useful and should be considered the appropriate surgical technique for the treatment of small-duct chronic pancreatitis without head dominance.

  11. Calculation of the diameter of the central retinal artery from noninvasive measurements in humans.

    PubMed

    Dorner, Guido T; Polska, Elzbieta; Garhöfer, Gerhard; Zawinka, Claudia; Frank, Barbara; Schmetterer, Leopold

    2002-12-01

    The aim of the present study was to calculate the diameter of the central retinal artery from results as obtained with non-invasive techniques in healthy young subjects. Twenty-four healthy male subjects participated in this study. Total retinal blood flow was calculated from combined bi-directional laser Doppler velocimetry and measurement of retinal venous diameters using the Zeiss retinal vessel analyzer. Using these techniques red blood cell velocity and vessel diameters of all visible veins entering the optic nerve head were measured and total retinal blood flow was calculated. Blood flow velocity in the central retinal artery was measured with color Doppler imaging. Form these outcome parameters the diameter of the central retinal artery was calculated for each subject individually. In the present study cohort the mean retinal blood flow was 38.1 +/- 9.1 microl/min and the mean flow velocity in the central retinal artery was 6.3 +/- 1.2 cm/s. From these data we calculated a mean diameter of the central retinal artery of 163 +/- 17 microm. Our results are in good agreement with data obtained from in vitro studies. The data of the present study also indicate that one needs to be careful to interpret velocity data from the central retinal artery in terms of retinal blood flow.

  12. Finger-powered microfluidic systems using multilayer soft lithography and injection molding processes.

    PubMed

    Iwai, Kosuke; Shih, Kuan Cheng; Lin, Xiao; Brubaker, Thomas A; Sochol, Ryan D; Lin, Liwei

    2014-10-07

    Point-of-care (POC) and disposable biomedical applications demand low-power microfluidic systems with pumping components that provide controlled pressure sources. Unfortunately, external pumps have hindered the implementation of such microfluidic systems due to limitations associated with portability and power requirements. Here, we propose and demonstrate a 'finger-powered' integrated pumping system as a modular element to provide pressure head for a variety of advanced microfluidic applications, including finger-powered on-chip microdroplet generation. By utilizing a human finger for the actuation force, electrical power sources that are typically needed to generate pressure head were obviated. Passive fluidic diodes were designed and implemented to enable distinct fluids from multiple inlet ports to be pumped using a single actuation source. Both multilayer soft lithography and injection molding processes were investigated for device fabrication and performance. Experimental results revealed that the pressure head generated from a human finger could be tuned based on the geometric characteristics of the pumping system, with a maximum observed pressure of 7.6 ± 0.1 kPa. In addition to the delivery of multiple, distinct fluids into microfluidic channels, we also employed the finger-powered pumping system to achieve the rapid formation of both water-in-oil droplets (106.9 ± 4.3 μm in diameter) and oil-in-water droplets (75.3 ± 12.6 μm in diameter) as well as the encapsulation of endothelial cells in droplets without using any external or electrical controllers.

  13. Apparatus For Eddy-Current Inspection Of Bolts

    NASA Technical Reports Server (NTRS)

    Amos, Jay M.

    1994-01-01

    Eddy-current apparatus for inspection of bolts, studs, and other threaded fasteners detects flaws in threads, shanks, and head fillets. With help of apparatus, technician quickly inspects fasteners of various dimensions. Accommodates fasteners with diameters from 0.190 in. to 1 in. and with lengths up to 5 in. Basic design modified to accommodate fasteners of other sizes.

  14. Generational changes in the growth of children from Maribor and Slovenia.

    PubMed

    Bigec, Martin

    2013-05-01

    Among the numerous factors which influence a child's growth and development are also factors of changeable socio-economic environment and life style. Our aim was to evaluate these changes and contribute to preventive measures and evaluation of a child's growth in pediatric practice. Therefore, we decided to estimate the state of body growth in two generations of children from Maribor at five and six years of age of both gender, establish secular changes and define standards. On a representative sample (gender and age) of 1461 children from Maribor measured in 1996 and a sample of 608 children from Maribor, measured in 1966, 28 body features were studied and compared in each population unit. Variables were statistically and epidemiologically assessed and results were controlled by a test. The following anthropometric differences were significant: in 5-year old boys the measures in the 1996 generation are statistically higher than in 1966 - foot length, head length, upper arm skinfold, subscapular skinfold, arm length, arm diameter, upper thigh skinfold, stature (length), suprailiac skinfold, and body weight. Decreased measures are: abdomen circumference, knee circumference, sitting height, elbow circumference, biacromial diameter, and face heigth. In 6-year old boys additional features have increased in comparison with the year 1966: sternal height, tight circumference, hip width, chest circumference; following measures have decreased: face height, head circumference. In 5-year old girls: increased measures in comparison with the generation from 1966 are: lower leg length, head length, ankle circumference, upper arm skinfold, body weight, billiac diameter, body height, subscapular skinfold, chest circumference, hip circumference, sternal height, suprailiac skinfold, decreased measures are: head circumference, elbow circumference, face circumference, shoulder with, sitting height. In 6-year old girls additional measures are increased: wrist circumference, arm length and chest circumference. Changing trends show an increased tendency towards decrease or increase of most body measurements. In everyday practice the most commonly used measurements are: body mass, head circumference, body length in babies and body height in pre-school children. Our measurements proved, with a p-value of 0.001, that measurements of children in 1966, also shown in diagrams, are significantly different from measurements in 1996. In the second part of this paper we present a part of the anthropometric measurement study carried out for the standardization of the DENVER II developmental screening test. There were 1596 healthy Slovene children between zero and six and half years of age included into the observation. Children come from Maribor, Koper, Velenje and Ljubljana. We used the Cameron's measurement and statistical method. Diagrams were made for following body measures: body mass, body height, head circumference, upper arm circumference, thigh circumference and body mass index. A comparative analysis with the Euro-Growth study showed that our results correspond with the European standards. Therefore, our results are suggested to be applied in everyday pediatric practice.

  15. Mechanical consequences of core drilling and bone-grafting on osteonecrosis of the femoral head.

    PubMed

    Brown, T D; Pedersen, D R; Baker, K J; Brand, R A

    1993-09-01

    We employed an anatomically realistic three-dimensional finite-element model to explore several biomechanical variables involved in coring or bone-grafting of a segmentally necrotic femoral head. The mechanical efficacy of several variants of these procedures was indexed in terms of their alteration of the stress:strength ratio in at-risk necrotic cancellous bone. For coring alone, the associated structural compromise was generally modest, provided that the tract did not extend near the subchondral plate. Cortical bone-grafting was potentially of great structural benefit for femoral heads in which the graft penetrated deeply into the superocentral or lateral aspect of the lesion, ideally with abutment against the subchondral plate. By contrast, central or lateral grafts that stopped well short of the subchondral plate were contraindicated biomechanically because they caused marked elevations in stress on the necrotic cancellous bone. Calculated levels of stress were relatively insensitive to variations in the diameter of the graft.

  16. The effect of hardhats on head and neck response to vertical impacts from large construction objects.

    PubMed

    Suderman, Bethany L; Hoover, Ryan W; Ching, Randal P; Scher, Irving S

    2014-12-01

    We evaluated the effectiveness of hardhats in attenuating head acceleration and neck force in vertical impacts from large construction objects. Two weight-matched objects (lead shot bag and concrete block) weighing 9.1 kg were dropped from three heights (0.91 m, 1.83 m and 2.74 m) onto the head of a 50th percentile male Hybrid III anthropomorphic test device (ATD). Two headgear conditions were tested: no head protection and an ANSI Type-I, Class-E hardhat. A third headgear condition (snow sport helmet) was tested at 1.83 m for comparison with the hardhat. Hardhats significantly reduced the resultant linear acceleration for the concrete block impacts by 70-95% when compared to the unprotected head condition. Upper neck compression was also significantly reduced by 26-60% with the use of a hardhat when compared to the unprotected head condition for the 0.91 and 1.83 m drop heights for both lead shot and concrete block drop objects. In this study we found that hardhats can be effective in reducing both head accelerations and compressive neck forces for large construction objects in vertical impacts. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. Large eccentric laser angioplasty catheter

    NASA Astrophysics Data System (ADS)

    Taylor, Kevin D.; Reiser, Christopher

    1997-05-01

    In response to recent demand for increased debulking of large diameter coronary vascular segments, a large eccentric catheter for excimer laser coronary angioplasty has been developed. The outer tip diameter is 2.0 mm and incorporates approximately 300 fibers of 50 micron diameter in a monorail- type percutaneous catheter. The basic function of the device is to ablate a coronary atherosclerotic lesion with 308 nm excimer laser pulses, while passing the tip of the catheter through the lesion. By employing multiple passes through the lesion, rotating the catheter 90 degrees after each pass, we expect to create luminal diameters close to 3 mm with this device. Design characteristics, in-vitro testing, and initial clinical experience is presented.

  18. Insufficient acetabular version increases blood metal ion levels after metal-on-metal hip resurfacing.

    PubMed

    Hart, Alister J; Skinner, John A; Henckel, Johann; Sampson, Barry; Gordon, Fabiana

    2011-09-01

    Many factors affect the blood metal ion levels after metal-on-metal (MOM) hip arthroplasty. The main surgically adjustable variable is the amount of coverage of the head provided by the cup which is a function of the inclination and version angles. However, most studies have used plain radiographs which have questionable precision and accuracy, particularly for version and large diameter metal heads; further, these studies do not simultaneously assess version and inclination. Thus the relationship between version and blood metal ions levels has not been resolved. We determined whether cup inclination and version influence blood metal ion levels while adjusting for age at assessment, gender, body mass index, horizontal femoral offset, head size, manufacturer hip type, and Oxford hip score. We prospectively followed 100 individuals (51 females, 49 males) with unilateral MOM hip resurfacing who underwent clinical assessment, CT scanning, and blood metal ion measurement. Multiple regression analysis was used to determine which variables were predictors of blood metal ion levels and to model the effect of these variables. Only cup inclination, version angles, and gender influenced blood cobalt or chromium levels. Cobalt and chromium levels positively correlated with inclination angle and negatively correlated with version angle. The effect of changes in version angle was less than for inclination angle. Based on our observations, we developed a formula to predict the effect of these parameters on metal ion levels. Our data suggest insufficient cup version can cause high blood metal ions after MOM hip arthroplasty. We were unable to show that excessive version caused high levels. Level II, prognostic study. See Guidelines for Authors for a complete description of levels of evidence.

  19. Status and trends of bottomland hardwood forests in the mid-Atlantic Region

    Treesearch

    Anita Rose; Steve Meadows

    2016-01-01

    Bottomland hardwood forests cover approximately 2.9 million acres of the Coastal Plain and Piedmont region of Virginia and North Carolina. As of 2014, 59 percent of bottomland hardwood forests were in the large-diameter stand-size class. Between 2002 and 2014, area of large-diameter sized stands increased, while that of medium- and small-diameter stands decreased,...

  20. The Evolution and Fate of Saturn's Stratospheric Vortex: Infrared Spectroscopy from Cassini

    NASA Technical Reports Server (NTRS)

    Fletcher, Leigh N.; Hesman, B. E.; Arhterberg, R. K.; Bjoraker, G.; Irwin, P. G. J.; Hurley, J.; Sinclair, J.; Gorius, N.; Orton, G. S.; Read, P. L.; hide

    2012-01-01

    The planet-encircling springtime storm in Saturn's troposphere (December 2010-July 2011) produced dramatic perturbations to stratospheric temperatures, winds and composition at mbar pressures that persisted long after the tropospheric disturbance had abated. Observations from the Cassini Composite Infrared Spectrometer (CIRS), supported by ground-based imaging from the VISIR instrument on the Very Large Telescope,is used to track the evolution of a large, hot stratospheric anticyclone between January 2011 and the present day. The evolutionary sequence can be divided into three phases: (I) the formation and intensification of two distinct warm airmasses near 0.5 mbar between 25 and 35N (one residing directly above the convective storm head) between January-April 2011, moving westward with different zonal velocities; (II) the merging of the warm airmasses to form the large single 'stratospheric beacon' near 40N between April and June 2011, dissociated from the storm head and at a higher pressure (2 mbar) than the original beacons; and (III) the mature phase characterized by slow cooling and longitudinal shrinkage of the anticyclone since July 2011, moving west with a near-constant velocity of 2.70+/-0.04 deg/day (-24.5+/-0.4 m/s at 40N). Peak temperatures of 220 K at 2 mbar were measured on May 5th 2011 immediately after the merger, some 80 K warmer than the quiescent surroundings. Thermal winds hear calculations in August 2011 suggest clockwise peripheral velocities of 200400 mls at 2 mbar, defining a peripheral collar with a width of 65 degrees longitude (50,000 km in diameter) and 25 degrees latitude. Stratospheric acetylene (C2H2) was uniformly enhanced by a factor of three within the vortex, whereas ethane (C2H6) remained unaffected. We will discuss the thermal and chemical characteristics of Saturn's beacon in its mature phase, and implications for stratospheric vortices on other giant planets.

  1. Vacuum extraction failure is associated with a large head circumference.

    PubMed

    Kabiri, Doron; Lipschuetz, Michal; Cohen, Sarah M; Yagel, Oren; Levitt, Lorinne; Herzberg, Shmuel; Ezra, Yossef; Yagel, Simcha; Amsalem, Hagai

    2018-04-24

    To determine whether large head circumference increases the risk of vacuum extraction failure. This EMR-based study included all attempted vacuum extractions performed in a tertiary center between January 2010 and June 2015. All term singleton live births were eligible. Cases were divided into four groups: head circumference ≥90th percentile both with birth weight ≥90th percentile and <90th percentile and fetal head circumference <90th percentile with birth weight ≥90th and <90th percentile. Risk of failed vacuum extraction was compared among these groups. Other neonatal and maternal parameters were also evaluated as potential risk factors. Multinomial multivariable regression provided adjusted odds ratio for vacuum extraction failure while controlling for potential confounders. During the study period, 48,007 deliveries met inclusion criteria, of which 3835 had an attempt at vacuum extraction. We identified 215 (5.6%) cases of vacuum extraction failure. The adjusted odds ratios (aOR) for vacuum extraction failure in cases of large fetal head circumference was 2.31 (95%CI, 1.7-3.15, p < .001). Primiparity, prolonged second stage and occipito-posterior presentation were also found to be significant risk factors for failed vacuum extraction. In this study, we found that large head circumference was associated with vacuum extraction failure rather than high birth weight.

  2. Determination of cup-to-disc ratio of optical nerve head for diagnosis of glaucoma on stereo retinal fundus image pairs

    NASA Astrophysics Data System (ADS)

    Muramatsu, Chisako; Nakagawa, Toshiaki; Sawada, Akira; Hatanaka, Yuji; Hara, Takeshi; Yamamoto, Tetsuya; Fujita, Hiroshi

    2009-02-01

    A large cup-to-disc (C/D) ratio, which is the ratio of the diameter of the depression (cup) to that of the optical nerve head (ONH, disc), can be one of the important signs for diagnosis of glaucoma. Eighty eyes, including 25 eyes with the signs of glaucoma, were imaged by a stereo retinal fundus camera. An ophthalmologist provided the outlines of cup and disc on a regular monitor and on the stereo display. The depth image of the ONH was created by determining the corresponding pixels in a pair of images based on the correlation coefficient in localized regions. The areas of the disc and cup were determined by use of the red component in one of the color images and by use of the depth image, respectively. The C/D ratio was determined based on the largest vertical lengths in the cup and disc areas, which was then compared with that by the ophthalmologist. The disc areas determined by the computerized method agreed relatively well with those determined by the ophthalmologist, whereas the agreement for the cup areas was somewhat lower. When C/D ratios were employed for distinction between the glaucomatous and non-glaucomatous eyes, the area under the receiver operating characteristic curve (AUC) was 0.83. The computerized analysis of ONH can be useful for diagnosis of glaucoma.

  3. Evaluation of a flexible bronchoscope prototype designed for bronchoscopy during mechanical ventilation: a proof-of-concept study.

    PubMed

    Nay, M-A; Auvet, A; Mankikian, J; Herve, V; Dequin, P-F; Guillon, A

    2017-06-01

    Bronchoscopy during mechanical ventilation of patients' lungs significantly affects ventilation because of partial obstruction of the tracheal tube, and may thus be omitted in the most severely ill patients. It has not previously been possible to reduce the external diameter of the bronchoscope without reducing the diameter of the suction channel, thus reducing the suctioning capacity of the device. We believed that a better-designed bronchoscope could improve the safety of bronchoscopy in patients whose lungs were ventilated. We designed a flexible bronchoscope prototype with a drumstick-shaped head consisting of a long, thin proximal portion; a short and large distal portion for camera docking; and a large suction channel throughout the length of the device. The aims of our study were to test the impact of our prototype on mechanical ventilation when inserted into the tracheal tube, and to assess suctioning capacity. We first tested the efficiency of the suction channel, and demonstrated that the suction flow of the prototype was similar to that of conventional adult bronchoscopes. We next evaluated the consequences of bronchoscopy when using the prototype on minute ventilation and intrathoracic pressures during mechanical ventilation: firstly, in vitro using a breathing simulator; and secondly, in vivo using a porcine model of pulmonary ventilation. The insertion of adult bronchoscopes into the tracheal tube immediately impaired the protective ventilation strategy employed, whereas the prototype preserved it. For the first time, we have developed an innovative flexible bronchoscope designed for bronchoscopy during invasive mechanical ventilation, that both preserved the protective ventilation strategy, and enabled efficient suction flow. © 2017 The Association of Anaesthetists of Great Britain and Ireland.

  4. Heat flow study of the Emeishan large igneous province region: Implications for the geodynamics of the Emeishan mantle plume

    NASA Astrophysics Data System (ADS)

    Jiang, Qiang; Qiu, Nansheng; Zhu, Chuanqing

    2018-01-01

    The Emeishan large igneous province (ELIP) is widely considered to be a consequence of a mantle plume. The supporting evidence includes rapid emplacement, voluminous flood basalt eruptions, and high mantle potential temperature estimates. Several studies have suggested that there was surface uplift prior to the eruption of the Emeishan flood basalts. Additionally, the plume's lateral extent is hard to constrain and has been variously estimated to be 800-1400 km in diameter. In this study, we analyzed present-day heat flow data and reconstructed the Permian paleo-heat flow using vitrinite reflectance and zircon (U-Th)/He thermochronology data in the ELIP region and discussed implications for the geodynamics of the Emeishan mantle plume. The present-day heat flow is higher in the inner and intermediate zones than in the outer zone, with a decrease of average heat flow from 76 mW/m2 to 51 mW/m2. Thermal history modeling results show that an abnormal high paleo-heat flow of 90-110 mW/m2 was caused by the Emeishan mantle plume activity. Based on the present-day heat flow data, we can calculate that there is lithospheric thinning in the central ELIP region, which may be due to the destruction of the lithosphere by mantle plume upwelling and magmatic underplating. The Permian paleo-heat flow anomaly implies that there was a temperature anomaly in the mantle. The ascending high-temperature mantle plume and the thinned lithosphere may have induced the large-scale uplift in the ELIP region. According to the range of the surface heat flow anomaly, it can be estimated that the diameter of the flattened head of the Emeishan mantle plume could have reached 1600-1800 km. Our research provides new insights into the geodynamics of the Emeishan mantle plume through study of heat flow.

  5. Radiation Dose to the Lens of the Eye from Computed Tomography Scans of the Head

    NASA Astrophysics Data System (ADS)

    Januzis, Natalie Ann

    While it is well known that exposure to radiation can result in cataract formation, questions still remain about the presence of a dose threshold in radiation cataractogenesis. Since the exposure history from diagnostic CT exams is well documented in a patient's medical record, the population of patients chronically exposed to radiation from head CT exams may be an interesting area to explore for further research in this area. However, there are some challenges in estimating lens dose from head CT exams. An accurate lens dosimetry model would have to account for differences in imaging protocols, differences in head size, and the use of any dose reduction methods. The overall objective of this dissertation was to develop a comprehensive method to estimate radiation dose to the lens of the eye for patients receiving CT scans of the head. This research is comprised of a physics component, in which a lens dosimetry model was derived for head CT, and a clinical component, which involved the application of that dosimetry model to patient data. The physics component includes experiments related to the physical measurement of the radiation dose to the lens by various types of dosimeters placed within anthropomorphic phantoms. These dosimeters include high-sensitivity MOSFETs, TLDs, and radiochromic film. The six anthropomorphic phantoms used in these experiments range in age from newborn to adult. First, the lens dose from five clinically relevant head CT protocols was measured in the anthropomorphic phantoms with MOSFET dosimeters on two state-of-the-art CT scanners. The volume CT dose index (CTDIvol), which is a standard CT output index, was compared to the measured lens doses. Phantom age-specific CTDIvol-to-lens dose conversion factors were derived using linear regression analysis. Since head size can vary among individuals of the same age, a method was derived to estimate the CTDIvol-to-lens dose conversion factor using the effective head diameter. These conversion factors were derived for each scanner individually, but also were derived with the combined data from the two scanners as a means to investigate the feasibility of a scanner-independent method. Using the scanner-independent method to derive the CTDIvol-to-lens dose conversion factor from the effective head diameter, most of the fitted lens dose values fell within 10-15% of the measured values from the phantom study, suggesting that this is a fairly accurate method of estimating lens dose from the CTDIvol with knowledge of the patient's head size. Second, the dose reduction potential of organ-based tube current modulation (OB-TCM) and its effect on the CTDIvol-to-lens dose estimation method was investigated. The lens dose was measured with MOSFET dosimeters placed within the same six anthropomorphic phantoms. The phantoms were scanned with the five clinical head CT protocols with OB-TCM enabled on the one scanner model at our institution equipped with this software. The average decrease in lens dose with OB-TCM ranged from 13.5 to 26.0%. Using the size-specific method to derive the CTDIvol-to-lens dose conversion factor from the effective head diameter for protocols with OB-TCM, the majority of the fitted lens dose values fell within 15-18% of the measured values from the phantom study. Third, the effect of gantry angulation on lens dose was investigated by measuring the lens dose with TLDs placed within the six anthropomorphic phantoms. The 2-dimensional spatial distribution of dose within the areas of the phantoms containing the orbit was measured with radiochromic film. A method was derived to determine the CTDIvol-to-lens dose conversion factor based upon distance from the primary beam scan range to the lens. The average dose to the lens region decreased substantially for almost all the phantoms (ranging from 67 to 92%) when the orbit was exposed to scattered radiation compared to the primary beam. The effectiveness of this method to reduce lens dose is highly dependent upon the shape and size of the head, which influences whether or not the angled scan range coverage can include the entire brain volume and still avoid the orbit. The clinical component of this dissertation involved performing retrospective patient studies in the pediatric and adult populations, and reconstructing the lens doses from head CT examinations with the methods derived in the physics component. The cumulative lens doses in the patients selected for the retrospective study ranged from 40 to 1020 mGy in the pediatric group, and 53 to 2900 mGy in the adult group. This dissertation represents a comprehensive approach to lens of the eye dosimetry in CT imaging of the head. The collected data and derived formulas can be used in future studies on radiation-induced cataracts from repeated CT imaging of the head. Additionally, it can be used in the areas of personalized patient dose management, and protocol optimization and clinician training.

  6. Subdermal liposuction.

    PubMed

    Gasperoni, C; Salgarello, M; Emiliozzi, P; Gargani, G

    1990-01-01

    Liposuction is a widely used technique today and indications are that it is becoming even more popular due to new technical refinements. The use of cannulae with a smaller diameter allows suction of the fat immediately under the dermis. The cannula we use to perform this new kind of fat suction is straight and has an external diameter of less than 2 mm. This cannula, the so-called Mercedes cannula, has a bullet tip and a three-hole head. Moreover, the holes are not round but are slit-shaped and oriented in the same plane at 120 degrees. This cannula is specifically designed to produce less trauma. The cannula with one downward-facing orifice is not suitable for suction of the subdermal layer and an upward-facing orifice would be too traumatic. The advantage of this new technique, apart from the possibility of treating patients with very slight adiposity, is to allow an effective skin retraction. When a large amount of fat has already been aspirated, residual deformities can occur. These skin irregularities represent the lack of an effective cutaneous retraction mostly due to the permanence of the subdermal fat. In fact, the presence of a thick subdermal adipose layer decreases the possibility of skin retraction. Therefore, indications for liposuction of the subdermal fat are mainly the slight adiposities and the remnant deformities of a previous liposuction operation. Moreover, this technique is applied to every lipoplasty whenever better skin retraction is needed.

  7. Measurement of aspheric mirror by nanoprofiler using normal vector tracing

    NASA Astrophysics Data System (ADS)

    Kitayama, Takao; Shiraji, Hiroki; Yamamura, Kazuya; Endo, Katsuyoshi

    2016-09-01

    Aspheric or free-form optics with high accuracy are necessary in many fields such as third-generation synchrotron radiation and extreme-ultraviolet lithography. Therefore the demand of measurement method for aspherical or free-form surface with nanometer accuracy increases. Purpose of our study is to develop a non-contact measurement technology for aspheric or free-form surfaces directly with high repeatability. To achieve this purpose we have developed threedimensional Nanoprofiler which detects normal vectors of sample surface. The measurement principle is based on the straightness of laser light and the accurate motion of rotational goniometers. This machine consists of four rotational stages, one translational stage and optical head which has the quadrant photodiode (QPD) and laser source. In this measurement method, we conform the incident light beam to reflect the beam by controlling five stages and determine the normal vectors and the coordinates of the surface from signal of goniometers, translational stage and QPD. We can obtain three-dimensional figure from the normal vectors and their coordinates by surface reconstruction algorithm. To evaluate performance of this machine we measure a concave aspheric mirror with diameter of 150 mm. As a result we achieve to measure large area of 150mm diameter. And we observe influence of systematic errors which the machine has. Then we simulated the influence and subtracted it from measurement result.

  8. Use of a specially designed partially covered self-expandable metal stent (PSEMS) with a 40-mm diameter for the treatment of upper gastrointestinal suture or staple line leaks in 11 cases.

    PubMed

    Fischer, Andreas; Bausch, Dirk; Richter-Schrag, Hans-Juergen

    2013-02-01

    The use of self-expandable stents to treat postoperative leaks and fistula in the upper gastrointestinal (GI) tract is an established treatment for leaks of the upper GI tract. However, lumen-to-stent size discrepancies (i.e., after sleeve gastrectomy or esophageal resection) may lead to insufficient sealing of the leaks requiring further surgical intervention. This is mainly due to the relatively small diameter (≤30 mm) of commonly used commercial stents. To overcome this problem, we developed a novel partially covered stent with a shaft diameter of 36 mm and a flare diameter of 40 mm. From September 2008 to September 2010, 11 consecutive patients with postoperative leaks were treated with the novel large diameter stent (gastrectomy, n = 5; sleeve gastrectomy, n = 2; fundoplication after esophageal perforation, n = 2; Roux-en-Y gastric bypass, n = 1; esophageal resection, n = 1). Treatment with commercially available stents (shaft/flare: 23/28 mm and 24/30 mm) had been unsuccessful in three patients before treatment with the large diameter stent. Due to dislocation, the large diameter stent was anchored in four patients (2× intraoperatively with transmural sutures, 2× endoscopically with transnasally externalized threads). Treatment was successful in 11 of 11 patients. Stent placement and removal was easy and safe. The median residence time of the stent was 24 (range, 18-41) days. Stent dislocation occurred in four cases (36 %). It was treated by anchoring the stent. Mean follow-up was 25 (range, 14-40) months. No severe complication occurred during or after intervention and no patient was dysphagic. Using the novel large diameter, partially covered stent to seal leaks in the upper GI tract is safe and effective. The large diameter of the stent does not seem to injure the wall of the upper GI tract. However, stent dislocation sometimes requires anchoring of the stent with sutures or transnasally externalized threads.

  9. Fresnel Lens Characterization for Potential Use in an Unpiloted Atmospheric Vehicle DIAL Receiver System

    NASA Technical Reports Server (NTRS)

    Fastig, Shlomo; Deoung, Russell J.

    1998-01-01

    Acrylic plastic Fresnel lenses are very light and can have large diameters. Such lenses could be used in lidar telescope receivers if the focal spot is not too large or distorted. This research effort characterizes the focal spot diameter produced by a Fresnel lens with a diameter of 30.5 cm (12 in.). It was found that the focal spot diameter varied from 1.2 mm at 750 nm to 1.6 mm at 910 nm. The focal spot was irregular and not easily described by a Gaussian profile.

  10. Brown rot in inner heartwood: why large logs support characteristics saproxylic beetle assemblages of conservation concern

    Treesearch

    Marie Yee; Simon J. Grove; Alastair M.M. Richardson; Caroline L. Mohammed

    2006-01-01

    It is not clear why large diameter logs generally host saproxylic beetle assemblages that are different from those of small diameter logs. In a study in Tasmanian wet eucalypt forest, two size-classes of Eucalyptus obliqua logs (>100cm and 30-60cm diameter) were destructively sampled to assess their beetle fauna and the associations of this fauna...

  11. Measuring Diameters Of Large Vessels

    NASA Technical Reports Server (NTRS)

    Currie, James R.; Kissel, Ralph R.; Oliver, Charles E.; Smith, Earnest C.; Redmon, John W., Sr.; Wallace, Charles C.; Swanson, Charles P.

    1990-01-01

    Computerized apparatus produces accurate results quickly. Apparatus measures diameter of tank or other large cylindrical vessel, without prior knowledge of exact location of cylindrical axis. Produces plot of inner circumference, estimate of true center of vessel, data on radius, diameter of best-fit circle, and negative and positive deviations of radius from circle at closely spaced points on circumference. Eliminates need for time-consuming and error-prone manual measurements.

  12. Non-isothermal infiltration and tracer transport experiments on large soil columns

    NASA Astrophysics Data System (ADS)

    Sobotkova, Martina; Snehota, Michal; Cejkova, Eva; Tesar, Miroslav

    2016-04-01

    Isothermal and non-isothermal infiltration experiments were carried out in the laboratory on large undisturbed soil columns (19 cm in diameter, 25 cm high) taken at the experimental catchments Roklan (Sumava Mountains, Czech Republic) and Uhlirska (Jizera Mountains, Czech republic). The aim of the study was twofold. The first goal was to obtain water flow and heat transport data for indirect parameter estimation of thermal and hydraulic properties of soils from two sites by inverse modelling. The second aim was to investigate the extent of impact of the temperature on saturated hydraulic conductivity (Ksat) and dispersity of solute transport. The temperature of infiltrating water in isothermal experiment (20 °C) was equal to the initial temperature of the sample. For non-isothermal experiment water temperature was 5°C, while the initial temperature of the sample was 20°C as in previous case. The experiment was started by flooding the sample surface. Then water level was maintained at constant level throughout the infiltration run using the optical sensor and peristaltic pump. Concentration pulse of deuterium was applied at the top of the soil sample, during the steady state flow. Initial pressure head in the sample was close to field capacity. Two tensiometers and two temperature sensors were inserted in the soil sample in two depths (9 and 15 cm below the top of the sample). Two additional temperature sensors monitored the temperature entering and leaving the samples. Water drained freely through the perforated plate at the bottom of sample by gravity. Inflow and outflow water flux densities, water pressure heads and soil temperatures were monitored continuously during experiments. Effluent was sampled in regular time intervals and samples were analysed for deuterium concentrations by laser spectroscopy to develop breakthrough curves. The outcome of experiments are the series of measured water fluxes, pressure heads and temperatures ready for inverse modelling by dual permeability. The saturated hydraulic conductivity of soil columns was higher in the case of higher temperature of flowing water. The change was however not proportional to Ksat change induced by temperature change of viscosity only.

  13. Stabilization and mobility of the head, neck and trunk in horses during overground locomotion: comparisons with humans and other primates.

    PubMed

    Dunbar, Donald C; Macpherson, Jane M; Simmons, Roger W; Zarcades, Athina

    2008-12-01

    Segmental kinematics were investigated in horses during overground locomotion and compared with published reports on humans and other primates to determine the impact of a large neck on rotational mobility (> 20 deg.) and stability (< or = 20 deg.) of the head and trunk. Three adult horses (Equus caballus) performing walks, trots and canters were videotaped in lateral view. Data analysis included locomotor velocity, segmental positions, pitch and linear displacements and velocities, and head displacement frequencies. Equine, human and monkey skulls and cervical spines were measured to estimate eye and vestibular arc length during head pitch displacements. Horses stabilized all three segments in all planes during all three gaits, unlike monkeys and humans who make large head pitch and yaw rotations during walks, and monkeys that make large trunk pitch rotations during gallops. Equine head angular displacements and velocities, with some exceptions during walks, were smaller than in humans and other primates. Nevertheless, owing to greater off-axis distances, orbital and vestibular arc lengths remained larger in horses, with the exception of head-neck axial pitch during trots, in which equine arc lengths were smaller than in running humans. Unlike monkeys and humans, equine head peak-frequency ranges fell within the estimated range in which inertia has a compensatory stabilizing effect. This inertial effect was typically over-ridden, however, by muscular or ligamentous intervention. Thus, equine head pitch was not consistently compensatory, as reported in humans. The equine neck isolated the head from the trunk enabling both segments to provide a spatial reference frame.

  14. SmartEye and Polhemus data for vestibulo-ocular reflex and optokinetic reflex model.

    PubMed

    Le, Anh Son; Aoki, Hirofumi

    2018-06-01

    In this data article, this dataset included raw data of head and eye movement that collected by Polhemus (Polhemus Inc) and SmartEye (Smart Eye AB) equipment. Subjects who have driver license participated in this experiment. The experiment was conducted with a driving simulator that was controlled by CarSim (Mechanical simulation Co., Anna Arbor, MI) with the vehicle motion. This data set not only contained the eye and head movement but also had eye gaze, pupil diameter, saccades, and so on. It can be used for the parameter identification of the vestibulor-ocular reflex (VOR) model, simulation eye movement, as well as running other analysis related to eye movement.

  15. Kinematics of a Head-Neck Model Simulating Whiplash

    ERIC Educational Resources Information Center

    Colicchia, Giuseppe; Zollman, Dean; Wiesner, Hartmut; Sen, Ahmet Ilhan

    2008-01-01

    A whiplash event is a relative motion between the head and torso that occurs in rear-end automobile collisions. In particular, the large inertia of the head results in a horizontal translation relative to the thorax. This paper describes a simulation of the motion of the head and neck during a rear-end (whiplash) collision. A head-neck model that…

  16. Bulb turbine operating at medium head: XIA JIANG case study

    NASA Astrophysics Data System (ADS)

    Loiseau, F.; Desrats, C.; Petit, P.; Liu, J.

    2012-11-01

    With lots of references for 4-blade bulb turbines, such as these of Wu Jin Xia (4 units - 36.1 MW per unit - 9.2 m rated head), Chang Zhou (15 units - 46.7 MW per unit - 9.5 m rated head) and Tong Wan (4 units - 46.2 MW per unit - 11 m rated head), ALSTOM Power Hydro is one of the major suppliers of bulb turbines operating under medium head for the Chinese market. ALSTOM Power Hydro has been awarded in November 2010 a contract by Jiang Xi Province Xia Jiang Water Control Project Headquarters to equip Xia Jiang's new hydropower plant. The power dam is located on the Gan Jiang river, at about 160 km away from Nan Chang town in South Eastern China. The supply will consist in 5 bulb units including the furniture of both the turbine and its generator, for a total capacity of 200 MW, under a rated net head of 8.6 m. The prototype turbine is a 7.8 m diameter runner, rotating at 71.4 rpm speed. For this project, ALSTOM has proposed a fully new design of 4-blade bulb runner. This paper outlines the main steps of the hydraulic development. First of all, a fine tuning of the blade geometry was performed to enhance the runner behaviour at high loads and low heads, so that to fulfill the demanding requirements of efficiencies and maximum output. The challenge was also to keep an excellent cavitation behaviour, especially at the outer blade diameter in order to avoid cavitation erosion on the prototype. The shape of the blade was optimized by using the latest tools in computational fluid dynamics. Steady state simulations of the distributor and the runner were performed, in order to simulate more accurately the pressure fields on the blade and the velocity distribution at the outlet of the runner. Moreover, draft tube computations have been performed close to the design point and at higher loads. Then, a model fully homologous with the prototype was manufactured and tested at ALSTOM's laboratory in Grenoble (France). The model test results confirmed the predicted ones: the expected weighted average efficiency is higher than the guaranteed value and the maximum output was reached with a comfortable safety margin. A comparison of the experimental and numerical velocity probings under the runner is also proposed as an insight into the prediction of flow behaviour at the inlet of the draft tube.

  17. 76 FR 30101 - Certain Steel Nails From the People's Republic of China: Final Results of Antidumping Duty...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-24

    ... shaft length up to 12 inches. Certain steel nails include, but are not limited to, nails made of round... finishes, heads, shanks, point types, shaft lengths and shaft diameters. Finishes include, but are not... collated with adhesive or polyester film tape backed with a heat seal adhesive. Also excluded from the...

  18. Case study of landfill leachate recirculation using small-diameter vertical wells.

    PubMed

    Jain, Pradeep; Ko, Jae Hac; Kumar, Dinesh; Powell, Jon; Kim, Hwidong; Maldonado, Lizmarie; Townsend, Timothy; Reinhart, Debra R

    2014-11-01

    A case study of landfill liquids addition using small diameter (5 cm) vertical wells is reported. More than 25,000 m(3) of leachate was added via 134 vertical wells installed 3 m, 12 m, and 18 m deep over five years in a landfill in Florida, US. Liquids addition performance (flow rate per unit screen length per unit liquid head) ranged from 5.6×10(-8) to 3.6×10(-6) m(3) s(-1) per m screen length per m liquid head. The estimated radial hydraulic conductivity ranged from 3.5×10(-6) to 4.2×10(-4) m s(-1). The extent of lateral moisture movement ranged from 8 to 10 m based on the responses of moisture sensors installed around vertical well clusters, and surface seeps were found to limit the achievable liquids addition rates, despite the use of concrete collars under a pressurized liquids addition scenario. The average moisture content before (51 samples) and after (272 samples) the recirculation experiments were 23% (wet weight basis) and 45% (wet weight basis), respectively, and biochemical methane potential measurements of excavated waste indicated significant (p<0.025) decomposition. Copyright © 2014 Elsevier Ltd. All rights reserved.

  19. Remote biopsy darting and marking of polar bears

    USGS Publications Warehouse

    Pagano, Anthony M.; Peacock, Elizabeth; McKinney, Melissa A.

    2014-01-01

    Remote biopsy darting of polar bears (Ursus maritimus) is less invasive and time intensive than physical capture and is therefore useful when capture is challenging or unsafe. We worked with two manufacturers to develop a combination biopsy and marking dart for use on polar bears. We had an 80% success rate of collecting a tissue sample with a single biopsy dart and collected tissue samples from 143 polar bears on land, in water, and on sea ice. Dye marks ensured that 96% of the bears were not resampled during the same sampling period, and we recovered 96% of the darts fired. Biopsy heads with 5 mm diameters collected an average of 0.12 g of fur, tissue, and subcutaneous adipose tissue, while biopsy heads with 7 mm diameters collected an average of 0.32 g. Tissue samples were 99.3% successful (142 of 143 samples) in providing a genetic and sex identification of individuals. We had a 64% success rate collecting adipose tissue and we successfully examined fatty acid signatures in all adipose samples. Adipose lipid content values were lower compared to values from immobilized or harvested polar bears, indicating that our method was not suitable for quantifying adipose lipid content.

  20. Do modern techniques improve core decompression outcomes for hip osteonecrosis?

    PubMed

    Marker, David R; Seyler, Thorsten M; Ulrich, Slif D; Srivastava, Siddharth; Mont, Michael A

    2008-05-01

    Core decompression procedures have been used in osteonecrosis of the femoral head to attempt to delay the joint destruction that may necessitate hip arthroplasty. The efficacy of core decompressions has been variable with many variations of technique described. To determine whether the efficacy of this procedure has improved during the last 15 years using modern techniques, we compared recently reported radiographic and clinical success rates to results of surgeries performed before 1992. Additionally, we evaluated the outcomes of our cohort of 52 patients (79 hips) who were treated with multiple small-diameter drillings. There was a decrease in the proportion of patients undergoing additional surgeries and an increase in radiographic success when comparing pre-1992 results to patients treated in the last 15 years. However, there were fewer Stage III hips in the more recent reports, suggesting that patient selection was an important reason for this improvement. The results of the small-diameter drilling cohort were similar to other recent reports. Patients who had small lesions and were Ficat Stage I had the best results with 79% showing no radiographic progression. Our study confirms core decompression is a safe and effective procedure for treating early stage femoral head osteonecrosis.

  1. Investigation of the Hydraulic Characteristics of Capillary Elements of the Injector Head of Jet Engines under Conditions of Isothermal Flow of A Liquid

    NASA Astrophysics Data System (ADS)

    Nigodjuk, V. E.; Sulinov, A. V.

    2018-01-01

    The article presents the results of an experimental study of the hydraulic characteristics of capillary elements of the injector head of jet engines in isothermal fluid flow and the proposed method of their calculation. The main geometric dimensions of the capillaries in the experiment were changed in the following range: Inner diameter from 0.16 to 0.36 mm, length from 4.3 to 158 mm and relative length from 25 to 614 and the inlet edge of the capillaries: sharp or smooth the leading edge. As the working fluid during the tests were distilled water, acetone and ethyl alcohol. Based on the results of a study of the dependences for calculation of ultimate losses in laminar and turbulent flow regimes in capillary tubes with smooth and sharp edges input. The influence of surface tension forces on loss of input on a sharp cutting edge. Experimentally confirmed the possibility of calculating the linear coefficient of hydraulic resistance of capillary tubes with a diameter of 0.16-0.36 mm in isothermal stable during the known dependencies that are valid for hydrodynamically smooth round tube.

  2. Fetal omphalocele ratios predict outcomes in prenatally diagnosed omphalocele.

    PubMed

    Montero, Freddy J; Simpson, Lynn L; Brady, Paula C; Miller, Russell S

    2011-09-01

    The objective of the study was to evaluate whether ratios considering omphalocele diameter relative to fetal biometric measurements perform better than giant omphalocele designation at predicting inability to achieve neonatal primary surgical closure. Cases of fetal omphalocele that underwent evaluation between May 2003 and July 2010 were identified. Inclusion was restricted to live births with plan for postnatal repair. Omphalocele diameter upon antenatal ultrasound was compared with abdominal circumference, femur length, and head circumference, yielding the respective omphalocele (O)/abdominal circumference (AC), O/femur length (FL), and O/head circumference (HC) ratios. The absolute measurements were used to classify giant lesions. Omphalocele ratios and giant omphalocele designations were evaluated as predictors of inability to achieve primary repair. Among 25 included cases, staged or delayed closure occurred in 52%. With an optimal cutoff of 0.21 or greater, O/HC best predicted the primary outcome (sensitivity, 84.6%; specificity, 58.3%; odds ratio, 7.7). The O/HC of 0.21 or greater outperformed giant designations. The O/HC of 0.21 or greater best predicted staged or delayed omphalocele closure. Giant omphalocele designation, regardless of definition, poorly predicted outcome. Copyright © 2011 Mosby, Inc. All rights reserved.

  3. Modeling Nanoparticle Wrapping or Translocation in Bilayer Membranes

    PubMed Central

    Curtis, Emily M.; Bahrami, Amir H.; Weikl, Thomas R.; Hall, Carol K.

    2015-01-01

    The spontaneous wrapping of nanoparticles by membranes is of increasing interest as nanoparticles become more prevalent in consumer products and hence more likely to enter the human body. We introduce a simulations-based tool that can be used to visualize the molecular level interaction between nanoparticles and bilayer membranes. By combining LIME, an intermediate resolution, implicit solvent model for phospholipids, with discontinuous molecular dynamics (DMD), we are able to simulate the wrapping or embedding of nanoparticles by 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) bilayer membranes. Simulations of hydrophilic nanoparticles with diameters from 10Å to 250Å show that hydrophilic nanoparticles with diameters greater than 20Å become wrapped while the nanoparticle with a diameter of 10Å does not . Instead this smaller particle became embedded in the bilayer surface where it could interact with the hydrophilic head groups of the lipid molecules. We also investigate the interaction between a DPPC bilayer and hydrophobic nanoparticles with diameters 10Å to 40Å. These nanoparticles do not undergo the wrapping process; instead they directly penetrate the membrane and embed themselves within the inner hydrophobic core of the bilayers. PMID:26260123

  4. Double diameter boring tool

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ashbaugh, F.N.; Murry, K.R.

    A method of boring two concentric holes of different depths is described utilizing an elongated boring tool having a tool axis of rotation, a longitudinally disposed tool centerline axis, and first and second transverse cutting edges at one end thereof extending across the boring tool, the second cutting edge being longitudinally rearwardly recessed with respect to the first cutting edge. The method consists of inserting the boring tool into an adjustable boring head, adjusting a distance B between the tool centerline axis and the tool axis of rotation such that the tool axis of rotation intersects a first boring areamore » of the first cutting edge; and boring the concentric holes having respectively larger and smaller diameters.« less

  5. A Novel Closed-Head Model of Mild Traumatic Brain Injury Using Focal Primary Overpressure Blast to the Cranium in Mice

    PubMed Central

    Guley, Natalie H.; Rogers, Joshua T.; Del Mar, Nobel A.; Deng, Yunping; Islam, Rafiqul M.; D'Surney, Lauren; Ferrell, Jessica; Deng, Bowei; Hines-Beard, Jessica; Bu, Wei; Ren, Huiling; Elberger, Andrea J.; Marchetta, Jeffrey G.; Rex, Tonia S.; Honig, Marcia G.

    2016-01-01

    Abstract Mild traumatic brain injury (TBI) from focal head impact is the most common form of TBI in humans. Animal models, however, typically use direct impact to the exposed dura or skull, or blast to the entire head. We present a detailed characterization of a novel overpressure blast system to create focal closed-head mild TBI in mice. A high-pressure air pulse limited to a 7.5 mm diameter area on the left side of the head overlying the forebrain is delivered to anesthetized mice. The mouse eyes and ears are shielded, and its head and body are cushioned to minimize movement. This approach creates mild TBI by a pressure wave that acts on the brain, with minimal accompanying head acceleration-deceleration. A single 20-psi blast yields no functional deficits or brain injury, while a single 25–40 psi blast yields only slight motor deficits and brain damage. By contrast, a single 50–60 psi blast produces significant visual, motor, and neuropsychiatric impairments and axonal damage and microglial activation in major fiber tracts, but no contusive brain injury. This model thus reproduces the widespread axonal injury and functional impairments characteristic of closed-head mild TBI, without the complications of systemic or ocular blast effects or head acceleration that typically occur in other blast or impact models of closed-skull mild TBI. Accordingly, our model provides a simple way to examine the biomechanics, pathophysiology, and functional deficits that result from TBI and can serve as a reliable platform for testing therapies that reduce brain pathology and deficits. PMID:26414413

  6. Prevention of unrecognized joint penetration during internal fixation of hip fractures: a geometric model based on Steinmetz Solid.

    PubMed

    Mao, Yujiang; Song, Jie; Wei, Jie; Wang, Manyi

    2010-01-01

    Unrecognized joint penetration (UJP) by screw penetration through the articular surface undetectable on routine anteroposterior (AP) and lateral radiographs can cause serious complications. We have developed a geometric model to analyze UJP, and methods for the prevention of the problem. A Steinmetz Solid (SS) is the overlapping portion between two identical, vertically intersecting cylinders. The AP and lateral radiographs of a femoral head (simplified as a sphere) are projections of two cylinder-shaped images. A screw that appears to be within the femoral head in fact only lies within the cylinder. A screw apparently within the femoral head on both AP and lateral images is only confined to the SS generated by two cylinders, but not necessarily confined to the femoral head itself. We have therefore analyzed UJP using a geometric model based on SS. The geometric basis of UJP lies in the fact that the SS is larger than the sphere (femoral head) with a volume ratio of 4: π. The theoretical risk of UJP for any screw therefore can be as high as 21.5% ((4-π)/4). In reality, screws are always carefully placed to ensure a distance between the screw's tip and the edge of femoral head (tip-to-edge distance, or TED). This TED effectively lowers the risk of UJP by reducing the size of the screw-confining SS. When the SS entirely fits into (internally tangential to) the femoral head, the risk of UJP approaches zero. A TED fulfilling this requirement can be regarded as safe (approximately 0.29 x femoral head radius). With a femoral head diameter of 5 cm, the safe TED is approximately 7 mm.

  7. Nuclear reactor heat transport system component low friction support system

    DOEpatents

    Wade, Elman E.

    1980-01-01

    A support column for a heavy component of a liquid metal fast breeder reactor heat transport system which will deflect when the pipes leading coolant to and from the heavy component expand or contract due to temperature changes includes a vertically disposed pipe, the pipe being connected to the heavy component by two longitudinally spaced cycloidal dovetail joints wherein the distal end of each of the dovetails constitutes a part of the surface of a large diameter cylinder and the centerlines of these large diameter cylinders intersect at right angles and the pipe being supported through two longitudinally spaced cycloidal dovetail joints wherein the distal end of each of the dovetails constitutes a part of the surface of a large diameter cylinder and the centerlines of these large diameter cylinders intersect at right angles, each of the cylindrical surfaces bearing on a flat and horizontal surface.

  8. Cutting Diameter Influences Early Survival and Growth of Several Populus Clones

    Treesearch

    Donald Dickmann; Howard Phipps; Daniel Netzer

    1980-01-01

    The effects of cutting diameter on early survival and growth of several Populus clones were studied in field tests in Wisconsin and Michigan. Generally, large diameter cuttings survived and grew better than small diameter cuttings. Response differences among clones were evident.

  9. Tackling the challenges of fully immersive head-mounted AR devices

    NASA Astrophysics Data System (ADS)

    Singer, Wolfgang; Hillenbrand, Matthias; Münz, Holger

    2017-11-01

    The optical requirements of fully immersive head mounted AR devices are inherently determined by the human visual system. The etendue of the visual system is large. As a consequence, the requirements for fully immersive head-mounted AR devices exceeds almost any high end optical system. Two promising solutions to achieve the large etendue and their challenges are discussed. Head-mounted augmented reality devices have been developed for decades - mostly for application within aircrafts and in combination with a heavy and bulky helmet. The established head-up displays for applications within automotive vehicles typically utilize similar techniques. Recently, there is the vision of eyeglasses with included augmentation, offering a large field of view, and being unobtrusively all-day wearable. There seems to be no simple solution to reach the functional performance requirements. Known technical solutions paths seem to be a dead-end, and some seem to offer promising perspectives, however with severe limitations. As an alternative, unobtrusively all-day wearable devices with a significantly smaller field of view are already possible.

  10. Hydraulic head applications of flow logs in the study of heterogeneous aquifers

    USGS Publications Warehouse

    Paillet, Frederick L.

    2001-01-01

    Permeability profiles derived from high-resolution flow logs in heterogeneous aquifers provide a limited sample of the most permeable beds or fractures determining the hydraulic properties of those aquifers. This paper demonstrates that flow logs can also be used to infer the large-scale properties of aquifers surrounding boreholes. The analysis is based on the interpretation of the hydraulic head values estimated from the flow log analysis. Pairs of quasi-steady flow profiles obtained under ambient conditions and while either pumping or injecting are used to estimate the hydraulic head in each water-producing zone. Although the analysis yields localized estimates of transmissivity for a few water-producing zones, the hydraulic head estimates apply to the farfield aquifers to which these zones are connected. The hydraulic head data are combined with information from other sources to identify the large-scale structure of heterogeneous aquifers. More complicated cross-borehole flow experiments are used to characterize the pattern of connection between large-scale aquifer units inferred from the hydraulic head estimates. The interpretation of hydraulic heads in situ under steady and transient conditions is illustrated by several case studies, including an example with heterogeneous permeable beds in an unconsolidated aquifer, and four examples with heterogeneous distributions of bedding planes and/or fractures in bedrock aquifers.

  11. Whole-globe biomechanics using high-field MRI.

    PubMed

    Voorhees, Andrew P; Ho, Leon C; Jan, Ning-Jiun; Tran, Huong; van der Merwe, Yolandi; Chan, Kevin; Sigal, Ian A

    2017-07-01

    The eye is a complex structure composed of several interconnected tissues acting together, across the whole globe, to resist deformation due to intraocular pressure (IOP). However, most work in the ocular biomechanics field only examines the response to IOP over smaller regions of the eye. We used high-field MRI to measure IOP induced ocular displacements and deformations over the whole globe. Seven sheep eyes were obtained from a local abattoir and imaged within 48 h using MRI at multiple levels of IOP. IOP was controlled with a gravity perfusion system and a cannula inserted into the anterior chamber. T2-weighted imaging was performed to the eyes serially at 0 mmHg, 10 mmHg, 20 mmHg and 40 mmHg of IOP using a 9.4 T MRI scanner. Manual morphometry was conducted using 3D visualization software to quantify IOP-induced effects at the globe scale (e.g. axial length and equatorial diameters) or optic nerve head scale (e.g. canal diameter, peripapillary sclera bowing). Measurement sensitivity analysis was conducted to determine measurement precision. High-field MRI revealed an outward bowing of the posterior sclera and anterior bulging of the cornea due to IOP elevation. Increments in IOP from 10 to 40 mmHg caused measurable increases in axial length in 6 of 7 eyes of 7.9 ± 5.7% (mean ± SD). Changes in equatorial diameter were minimal, 0.4 ± 1.2% between 10 and 40 mmHg, and in all cases less than the measurement sensitivity. The effects were nonlinear, with larger deformations at normal IOPs (10-20 mmHg) than at elevated IOPs (20-40 mmHg). IOP also caused measurable increases in the nasal-temporal scleral canal diameter of 13.4 ± 9.7% between 0 and 20 mmHg, but not in the superior-inferior diameter. This study demonstrates that high-field MRI can be used to visualize and measure simultaneously the effects of IOP over the whole globe, including the effects on axial length and equatorial diameter, posterior sclera displacement and bowing, and even changes in scleral canal diameter. The fact that the equatorial diameter did not change with IOP, in agreement with previous studies, indicates that a fixed boundary condition is a reasonable assumption for half globe inflation tests and computational models. Our results demonstrate the potential of high-field MRI to contribute to understanding ocular biomechanics, and specifically of the effects of IOP in large animal models. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Occupancy of tissue-specific cis-regulatory modules by Otx2 and TLE/Groucho for embryonic head specification.

    PubMed

    Yasuoka, Yuuri; Suzuki, Yutaka; Takahashi, Shuji; Someya, Haruka; Sudou, Norihiro; Haramoto, Yoshikazu; Cho, Ken W; Asashima, Makoto; Sugano, Sumio; Taira, Masanori

    2014-07-09

    Head specification by the head-selector gene, orthodenticle (otx), is highly conserved among bilaterian lineages. However, the molecular mechanisms by which Otx and other transcription factors (TFs) interact with the genome to direct head formation are largely unknown. Here we employ ChIP-seq and RNA-seq approaches in Xenopus tropicalis gastrulae and find that occupancy of the corepressor, TLE/Groucho, is a better indicator of tissue-specific cis-regulatory modules (CRMs) than the coactivator p300, during early embryonic stages. On the basis of TLE binding and comprehensive CRM profiling, we define two distinct types of Otx2- and TLE-occupied CRMs. Using these devices, Otx2 and other head organizer TFs (for example, Lim1/Lhx1 (activator) or Goosecoid (repressor)) are able to upregulate or downregulate a large battery of target genes in the head organizer. An underlying principle is that Otx marks target genes for head specification to be regulated positively or negatively by partner TFs through specific types of CRMs.

  13. Improving socket design to prevent difficult removal of locking screws.

    PubMed

    Lin, Chen-Huei; Chao, Ching-Kong; Tang, Yi-Hsuan; Lin, Jinn

    2018-03-01

    Reports of driver slippage leading to difficult locking screw removals have increased since the adoption of titanium for screw fabrication; the use of titanium is known to cause cross-threading and cold welding. Such problems occur most frequently in screws with hex sockets, and may cause serious surgical complications. This study aimed to improve screw socket design to prevent slippage and difficult screw removal. Three types of small sockets (hex, Torx, and cruciate) and six types of large sockets (hex, Torx, Octatorx, Torx+ I, Torx+ II, and Torx+ III) with screw head diameters of 5.5 mm were manufactured from titanium, and corresponding screwdrivers were manufactured from stainless steel. The screw heads and drivers were mounted on a material testing machine, and torsional tests were conducted to simulate screw usage in clinical settings at two insertion depths: 1 and 2 mm. Ten specimens were tested from each design, and the maximum torque and failure patterns were recorded and compared. For small sockets in 2 mm conditions, the hex with the largest driver core had the highest torque, followed by Torx and cruciate. In these tests, the drivers were twisted off in all specimens. However, under the 1 mm condition, the hex slipped and the torque decreased markedly. Overall, torque was higher for large sockets than for small sockets. The Octatorx, with a large core and simultaneous deformation of the driver and socket lobes, had the highest torque at almost twice that of the small hex. The hex had the lowest torque, a result of slippage in both the 1 and 2 mm conditions. Torx plus designs, with more designed degrees of freedom, were able to maintain a higher driving angle and larger core for higher torque. The hex design showed slipping tendencies with a marked decrease in torque, especially under conditions with inadequate driver engagement. Large sockets allowed for substantial increases in torque. The Torx, Octatorx, and Torx plus designs displayed better performance than the hexes. Improvements to the socket design could effectively prevent slippage and solve difficult screw removal problems. Copyright © 2018. Published by Elsevier Ltd.

  14. Optimizing Cluster Heads for Energy Efficiency in Large-Scale Heterogeneous Wireless Sensor Networks

    DOE PAGES

    Gu, Yi; Wu, Qishi; Rao, Nageswara S. V.

    2010-01-01

    Many complex sensor network applications require deploying a large number of inexpensive and small sensors in a vast geographical region to achieve quality through quantity. Hierarchical clustering is generally considered as an efficient and scalable way to facilitate the management and operation of such large-scale networks and minimize the total energy consumption for prolonged lifetime. Judicious selection of cluster heads for data integration and communication is critical to the success of applications based on hierarchical sensor networks organized as layered clusters. We investigate the problem of selecting sensor nodes in a predeployed sensor network to be the cluster heads tomore » minimize the total energy needed for data gathering. We rigorously derive an analytical formula to optimize the number of cluster heads in sensor networks under uniform node distribution, and propose a Distance-based Crowdedness Clustering algorithm to determine the cluster heads in sensor networks under general node distribution. The results from an extensive set of experiments on a large number of simulated sensor networks illustrate the performance superiority of the proposed solution over the clustering schemes based on k -means algorithm.« less

  15. Grandparent Headed Families and Head Start: Developing Effective Services.

    ERIC Educational Resources Information Center

    Dannison, Linda L.; Smith, Andrea B.

    Numerous challenges face the growing number of grandparent-headed households, including isolation from friends and social supports, and difficulties in caring for grandchildren exhibiting multiple needs. This paper describes a pilot program in which a university and a large county-wide Head Start program formed a partnership to focus on serving…

  16. Effects of turbulence on hydraulic heads and parameter sensitivities in preferential groundwater flow layers

    USGS Publications Warehouse

    Shoemaker, W. Barclay; Cunningham, Kevin J.; Kuniansky, Eve L.; Dixon, Joann F.

    2008-01-01

    A conduit flow process (CFP) for the Modular Finite Difference Ground‐Water Flow model, MODFLOW‐2005, has been created by the U.S. Geological Survey. An application of the CFP on a carbonate aquifer in southern Florida is described; this application examines (1) the potential for turbulent groundwater flow and (2) the effects of turbulent flow on hydraulic heads and parameter sensitivities. Turbulent flow components were spatially extensive in preferential groundwater flow layers, with horizontal hydraulic conductivities of about 5,000,000 m d−1, mean void diameters equal to about 3.5 cm, groundwater temperature equal to about 25°C, and critical Reynolds numbers less than or equal to 400. Turbulence either increased or decreased simulated heads from their laminar elevations. Specifically, head differences from laminar elevations ranged from about −18 to +27 cm and were explained by the magnitude of net flow to the finite difference model cell. Turbulence also affected the sensitivities of model parameters. Specifically, the composite‐scaled sensitivities of horizontal hydraulic conductivities decreased by as much as 70% when turbulence was essentially removed. These hydraulic head and sensitivity differences due to turbulent groundwater flow highlight potential errors in models based on the equivalent porous media assumption, which assumes laminar flow in uniformly distributed void spaces.

  17. Fetal Growth and Birth Anthropometrics in Metformin-Exposed Offspring Born to Mothers With PCOS.

    PubMed

    Hjorth-Hansen, Anna; Salvesen, Øyvind; Engen Hanem, Liv Guro; Eggebø, Torbjørn; Salvesen, Kjell Å; Vanky, Eszter; Ødegård, Rønnaug

    2018-02-01

    Metformin is used in an attempt to reduce pregnancy complications associated with polycystic ovary syndrome (PCOS). Little is known about the effect of metformin on fetal development and growth. To compare the effect of metformin versus placebo on fetal growth and birth anthropometrics in PCOS offspring compared with a reference population in relation to maternal body mass index (BMI). Post hoc analysis of a randomized controlled trial. Double-blind, placebo-controlled, multicenter study. 258 offspring born to mothers with PCOS. 2000 mg metformin (n = 131) or placebo (n = 121) from first trimester to delivery. Mean abdominal diameter and biparietal diameter (BPD) at gestational weeks 19 and 32. Head circumference (HC), birth length, and weight related to a reference population of healthy offspring, expressed as gestational age- and sex-adjusted z-scores. Metformin- versus placebo-exposed offspring had larger heads at gestational week 32 (BPD, 86.1 mm versus 85.2 mm; P = 0.03) and at birth (HC, 35.6 cm versus 35.1 cm; P < 0.01). Analyses stratified by maternal prepregnancy BMI, larger heads were observed only among offspring of overweight/obese mothers. Among normal-weight mothers, the effect of metformin compared with placebo was reduced length (z-score = -0.96 versus -0.42, P = 0.04) and weight (z-score = -0.44 versus 0.02; P = 0.03). Compared with the reference population, offspring born to PCOS mothers (placebo group) had reduced length (z-score = -0.40; 95% confidence interval, -0.60 to -0.40), but similar birth weight and HC. Metformin exposure resulted in larger head size in offspring of overweight mothers, traceable already in utero. Maternal prepregnancy BMI modified the effect of metformin on offspring anthropometrics. Anthropometrics of offspring born to PCOS mothers differed from those of the reference population. Copyright © 2017 Endocrine Society

  18. Feasibility of a miniature centrifugal rotary blood pump for low-flow circulation in children and infants.

    PubMed

    Takatani, Setsuo; Hoshi, Hideo; Tajima, Kennichi; Ohuchi, Katsuhiro; Nakamura, Makoto; Asama, Junichio; Shimshi, Tadahiko; Yoshikawa, Masaharu

    2005-01-01

    In this study, a seal-less, tiny centrifugal rotary blood pump was designed for low-flow circulatory support in children and infants. The design was targeted to yield a compact and priming volume of 5 ml with a flow rate of 0.5-4 l/min against a head pressure of 40-100 mm Hg. To meet the design requirements, the first prototype had an impeller diameter of 30 mm with six straight vanes. The impeller was supported with a needle-type hydrodynamic bearing and was driven with a six-pole radial magnetic driver. The external pump dimensions included a pump head height of 20 mm, diameter of 49 mm, and priming volume of 5 ml. The weight was 150 g, including the motor driver. In the mock circulatory loop, using fresh porcine blood, the pump yielded a flow of 0.5-4.0 l/min against a head pressure of 40-100 mm Hg at a rotational speed of 1800-4000 rpm using 1/4" inflow and outflow conduits. The maximum flow and head pressure of 5.25 l/min and 244 mm Hg, respectively, were obtained at a rotational speed of 4400 rpm. The maximum electrical-to-hydraulic efficiency occurred at a flow rate of 1.5-3.5 l/min and at a rotational speed of 2000-4400 rpm. The normalized index of hemolysis, which was evaluated using fresh porcine blood, was 0.0076 g/100 l with the impeller in the down-mode and a bearing clearance of 0.1 mm. Further refinement in the bearing and magnetic coupler are required to improve the hemolytic performance of the pump. The durability of the needle-type hydrodynamic bearing and antithrombotic performance of the pump will be performed before clinical applications. The tiny centrifugal blood pump meets the flow requirements necessary to support the circulation of pediatric patients.

  19. Early biometric lag in the prediction of small for gestational age neonates and preeclampsia.

    PubMed

    Schwartz, Nadav; Pessel, Cara; Coletta, Jaclyn; Krieger, Abba M; Timor-Tritsch, Ilan E

    2011-01-01

    An early fetal growth lag may be a marker of future complications. We sought to determine the utility of early biometric variables in predicting adverse pregnancy outcomes. In this retrospective cohort study, the crown-rump length at 11 to 14 weeks and the head circumference, biparietal diameter, abdominal circumference, femur length, humerus length, transverse cerebellar diameter, and estimated fetal weight at 18 to 24 weeks were converted to an estimated gestational age using published regression formulas. Sonographic fetal growth (difference between each biometric gestational age and the crown-rump length gestational age) minus expected fetal growth (number of days elapsed between the two scans) yielded the biometric growth lag. These lags were tested as predictors of small for gestational age (SGA) neonates (≤10th percentile) and preeclampsia. A total of 245 patients were included. Thirty-two (13.1%) delivered an SGA neonate, and 43 (17.6%) had the composite outcome. The head circumference, biparietal diameter, abdominal circumference, and estimated fetal weight lags were identified as significant predictors of SGA neonates after adjusted analyses (P < .05). The addition of either the estimated fetal weight or abdominal circumference lag to maternal characteristics alone significantly improved the performance of the predictive model, achieving areas under the curve of 0.72 and 0.74, respectively. No significant association was found between the biometric lag variables and the development of preeclampsia. Routinely available biometric data can be used to improve the prediction of adverse outcomes such as SGA. These biometric lags should be considered in efforts to develop screening algorithms for adverse outcomes.

  20. Long-term Outcome of Multiple Small-diameter Drilling Decompression Combined with Hip Arthroscopy versus Drilling Alone for Early Avascular Necrosis of the Femoral Head.

    PubMed

    Li, Ji; Li, Zhong-Li; Zhang, Hao; Su, Xiang-Zheng; Wang, Ke-Tao; Yang, Yi-Meng

    2017-06-20

    Avascular necrosis of femoral head (AVNFH) typically presents in the young adults and progresses quickly without proper treatments. However, the optimum treatments for early stage of AVNFH are still controversial. This study was conducted to evaluate the therapeutic effects of multiple small-diameter drilling decompression combined with hip arthroscopy for early AVNFH compared to drilling alone. This is a nonrandomized retrospective case series study. Between April 2006 and November 2010, 60 patients (98 hips) with early stage AVNFH participated in this study. The patients underwent multiple small-diameter drilling decompression combined with hip arthroscopy in 26 cases/43 hips (Group A) or drilling decompression alone in 34 cases/55 hips (Group B). Patients were followed up at 6, 12, and 24 weeks, and every 6 months thereafter. Radiographs were taken at every follow-up, Harris scores were recorded at the last follow-up, the paired t-test was used to compare the postoperative Harris scores. Surgery effective rate of the two groups was compared using the Chi-square test. All patients were followed up for an average of 57.6 months (range: 17-108 months). Pain relief and improvement of hip function were assessed in all patients at 6 months after the surgery. At the last follow-up, Group A had better outcome with mean Harris' scores improved from 68.23 ± 11.37 to 82.07 ± 2.92 (t = -7.21, P = 0.001) than Group B with mean Harris' scores improved from 69.46 ± 9.71 to 75.79 ± 4.13 (t = -9.47, P = 0.037) (significantly different: t = -2.54, P = 0.017). The total surgery effective rate was also significantly different between Groups A and B (86.0% vs. 74.5%; χ2 = 3.69, P = 0.02). For early stage of AVNFH, multiple small-diameter drilling decompression combined with hip arthroscopy is more effective than drilling decompression alone.

  1. Investigation of Infant Brain with or without Hydrocephalous in Our Environment Using Anterior Transfontanelle Ultrasound Scan.

    PubMed

    Marchie, Tobechukwu T; Ayara, Charles O

    2013-01-01

    A prospective study aimed to suggest easy and simple reproducible ventricular site that will be basic measurement plane and normal dimension determined, correlated to sizes of infants for comparative evaluation of hydrocephalous infants and should be reproducible in follow-up. A prospective study done in University of Benin Teaching Hospital Benin, Nigeria. This study used 50 consecutive infants with Ultrasound scan (US) diagnosis of hydrocephalus and a control group of 50 US normal from 1(st) January 2007 to 30(th) June 2008. The infants were scan through the mid-patent anterior fontanelle in sagittal, and transverse planes with minor angulations to properly outline the ventricles and the position of measurement determined at the foramen of Monro of lateral ventricles and the diameter measured. The infants' weight, crown-heel length, and head circumference were measured and body mass index (BMI) calculated and correlated to lateral ventricular measurement. Data analysis was conducted using the Statistical Package for Social Sciences (SPSS Inc, USA), Version 11.0. There was no statistically sex and age-related difference. There is statistically comparative high mean weight and height and lower BMI in hydrocephalic infants as against the control group (P < 0.001). The mean head circumference for hydrocephalus was 45.6 (± 10.5 standard deviation [SD]), whereas the control group was 35.9 (± 2.7 SD) with P < 0.001. The mean diameter of the anterior horn of left and right lateral ventricles at the level of foramen of Monro in hydrocephalic subjects is 18.4 mm ± 14.3 mm and 20.1 mm ± 16.8 mm with median diameter of 14.1 mm and 15.2 mm, respectively, whereas control group is 2.5 mm ± 0.6 mm and 2.5 mm ± 0.7 mm with median diameter of 2.5 mm and 2.4 mm, respectively. Transfontanelle US was found highly useful in investigation of hydrocephalous in infant.

  2. Stabilization and mobility of the head, neck and trunk in horses during overground locomotion: comparisons with humans and other primates

    PubMed Central

    Dunbar, Donald C.; Macpherson, Jane M.; Simmons, Roger W.; Zarcades, Athina

    2009-01-01

    SUMMARY Segmental kinematics were investigated in horses during overground locomotion and compared with published reports on humans and other primates to determine the impact of a large neck on rotational mobility (>20deg.) and stability (≤20deg.) of the head and trunk. Three adult horses (Equus caballus) performing walks, trots and canters were videotaped in lateral view. Data analysis included locomotor velocity, segmental positions, pitch and linear displacements and velocities, and head displacement frequencies. Equine, human and monkey skulls and cervical spines were measured to estimate eye and vestibular arc length during head pitch displacements. Horses stabilized all three segments in all planes during all three gaits, unlike monkeys and humans who make large head pitch and yaw rotations during walks, and monkeys that make large trunk pitch rotations during gallops. Equine head angular displacements and velocities, with some exceptions during walks, were smaller than in humans and other primates. Nevertheless, owing to greater off-axis distances, orbital and vestibular arc lengths remained larger in horses, with the exception of head–neck axial pitch during trots, in which equine arc lengths were smaller than in running humans. Unlike monkeys and humans, equine head peak-frequency ranges fell within the estimated range in which inertia has a compensatory stabilizing effect. This inertial effect was typically over-ridden, however, by muscular or ligamentous intervention. Thus, equine head pitch was not consistently compensatory, as reported in humans. The equine neck isolated the head from the trunk enabling both segments to provide a spatial reference frame. PMID:19043061

  3. Effect of Booster Seat Design on Children’s Choice of Seating Positions During Naturalistic Riding

    PubMed Central

    Andersson, Marianne; Bohman, Katarina; Osvalder, Anna-Lisa

    2010-01-01

    The purpose of this naturalistic study was to investigate the effect of booster seat design on the choice of children’s seating positions during naturalistic riding. Data was collected through observations of children during in-vehicle riding by means of a film camera. The children were positioned in high back boosters in the rear seat while a parent drove the car. The study included two different booster designs: one with large head and torso side supports, and one with small head side supports and no torso side supports. Six children between three and six years of age participated in the study. Each child was observed in both boosters. The duration of the seating positions that each child assumed was quantified. The design with large side head supports resulted more often in seating positions without head and shoulder contact with the booster’s back. There was shoulder-to-booster back contact during an average of 45% of riding time in the seat with the large head side supports compared to 75% in the seat with the small head supports. The children in the study were seated with the head in front of the front edge of the head side supports more than half the time, in both boosters. Laterally, the children were almost constantly positioned between the side supports of the booster in both seats. The observed seating positions probably reduce the desired protective effect by the side supports in side impact, and may increase the probability of head impact with the vehicle interior in frontal impact. PMID:21050601

  4. Interactions among mechanisms of sexual selection on male body size and head shape in a sexually dimorphic fly.

    PubMed

    Bonduriansky, Russell; Rowe, Locke

    2003-09-01

    Darwin envisaged male-male and male-female interactions as mutually supporting mechanisms of sexual selection, in which the best armed males were also the most attractive to females. Although this belief continues to predominate today, it has been challenged by sexual conflict theory, which suggests that divergence in the interests of males and females may result in conflicting sexual selection. This raises the empirical question of how multiple mechanisms of sexual selection interact to shape targeted traits. We investigated sexual selection on male morphology in the sexually dimorphic fly Prochyliza xanthostoma, using indices of male performance in male-male and male-female interactions in laboratory arenas to calculate gradients of direct, linear selection on male body size and an index of head elongation. In male-male combat, the first interaction with a new opponent selected for large body size but reduced head elongation, whereas multiple interactions with the same opponent favored large body size only. In male-female interactions, females preferred males with relatively elongated heads, but male performance of the precopulatory leap favored large body size and, possibly, reduced head elongation. In addition, the amount of sperm transferred (much of which is ingested by females) was an increasing function of both body size and head elongation. Thus, whereas both male-male and male-female interactions favored large male body size, male head shape appeared to be subject to conflicting sexual selection. We argue that conflicting sexual selection may be a common result of divergence in the interests of the sexes.

  5. Fiber inhalability and head deposition in rats and humans. ...

    EPA Pesticide Factsheets

    Due to their dimensions and long durability, inhaled asbestos fibers clear slowly from lung airways. Retained fibers may injure the epithelium, interact with macrophages, or translocate to the interstitium to result in various respiratory diseases. Therefore, calculations of fiber inhalability, deposition, and retention in respiratory tract regions of both rats and humans are crucial, both to assess the health risk of fiber exposures and to facilitate inferences from rat inhalation studies. Rat inhalation experiments are underway at the EPA and NIEHS. A model of fiber inhalability and initial deposition in the human and rat nasal cavity was developed. Existing models for particles were extended to fibers by replacing particle diameter with an equivalent fiber diameter. Since fiber inhalability into the respiratory tract and deposition in the extra thoracic airways depended mainly on its inertia, equivalent impaction diameters were derived and substituted in expressions for spherical particle diameter to determine fiber inhalability and nasal losses. Fiber impaction diameter depended strongly on its orientation in the air. Highest inhalability was obtained when fibers were aligned perpendicular to the flow streamlines in the inhaled air. However, detailed calculations of fiber transport in slow moving air such as that in the atmosphere and in lung airways showed that fibers stayed primarily aligned (parallel) to the flow. Therefore, for inhalability calculations,

  6. Multivalent Lipid--DNA Complexes: Distinct DNA Compaction Regimes

    NASA Astrophysics Data System (ADS)

    Evans, Heather M.; Ahmad, A.; Ewert, K.; Safinya, C. R.

    2004-03-01

    Cationic liposomes (CL), while intrinsically advantageous in comparison to viruses, still have limited success for gene therapy and require more study. CL spontaneously self-assemble with DNA via counterion release, forming small particles approximately 200nm in diameter. X-ray diffraction reveals CL-DNA structures that are typically a multilamellar organization of lipids with DNA intercalated between the layers. We explore the structural properties of CL-DNA complexes formed with new multivalent lipids (Ewert et al, J. Med. Chem. 2002; 45:5023) that range from 2+ to 16+. Contrary to a simple prediction for the DNA interaxial spacing d_DNA based on a geometrical space-filling model, these lipids show dramatic DNA compaction, down to d_DNA ˜ 25 ÅVariations in the membrane charge density, σ _M, lead to distinct spacing regimes. We propose that this DNA condensation is controlled by a unique locking mechanism between the DNA double helix and the large, multivalent lipid head groups. Funded by NSF DMR-0203755 and NIH GM-59288.

  7. On the accuracy of the Head Impact Telemetry (HIT) System used in football helmets.

    PubMed

    Jadischke, Ron; Viano, David C; Dau, Nathan; King, Albert I; McCarthy, Joe

    2013-09-03

    On-field measurement of head impacts has relied on the Head Impact Telemetry (HIT) System, which uses helmet mounted accelerometers to determine linear and angular head accelerations. HIT is used in youth and collegiate football to assess the frequency and severity of helmet impacts. This paper evaluates the accuracy of HIT for individual head impacts. Most HIT validations used a medium helmet on a Hybrid III head. However, the appropriate helmet is large based on the Hybrid III head circumference (58 cm) and manufacturer's fitting instructions. An instrumented skull cap was used to measure the pressure between the head of football players (n=63) and their helmet. The average pressure with a large helmet on the Hybrid III was comparable to the average pressure from helmets used by players. A medium helmet on the Hybrid III produced average pressures greater than the 99th percentile volunteer pressure level. Linear impactor tests were conducted using a large and medium helmet on the Hybrid III. Testing was conducted by two independent laboratories. HIT data were compared to data from the Hybrid III equipped with a 3-2-2-2 accelerometer array. The absolute and root mean square error (RMSE) for HIT were computed for each impact (n=90). Fifty-five percent (n=49) had an absolute error greater than 15% while the RMSE was 59.1% for peak linear acceleration. Copyright © 2013 Elsevier Ltd. All rights reserved.

  8. Individual stem value recovery of modified and conventional tree-length systems in the southeastern United States

    Treesearch

    Amanda H. Lang; Shawn A. Baker; W. Dale Greene; Glen E. Murphy

    2010-01-01

    We compared value recovery of a modified treelength (MTL) logging system that measures product diameter and length using a Waratah 626 harvester head to that of a treelength (TL) system that estimates dimensions. A field test compared the actual value cut to the maximum potential value suggested by the log bucking optimization program Assessment of Value by Individual...

  9. Torsional stability of interference screws derived from bovine bone - a biomechanical study

    PubMed Central

    2010-01-01

    Background In the present biomechanical study, the torsional stability of different interference screws, made of bovine bone, was tested. Interference screws derived from bovine bone are a possible biological alternative to conventional metallic or bioabsorbable polymer interference screws. Methods In the first part of the study we compared the torsional stability of self-made 8 mm Interference screws (BC) and a commercial 8 mm interference screw (Tutofix®). Furthermore, we compared the torsional strength of BC screws with different diameters. For screwing in, a hexagon head and an octagon head were tested. Maximum breaking torques in polymethyl methacrylate resin were recorded by means of an electronic torque screw driver. In the second part of the study the tibial part of a bone-patellar tendon-bone graft was fixed in porcine test specimens using an 8 mm BC screw and the maximum insertion torques were recorded. Each interference screw type was tested 5 times. Results There was no statistically significant difference between the different 8 mm interference screws (p = 0.121). Pairwise comparisons did not reveal statistically significant differences, either. It was demonstrated for the BC screws, that a larger screw diameter significantly leads to higher torsional stability (p = 9.779 × 10-5). Pairwise comparisons showed a significantly lower torsional stability for the 7 mm BC screw than for the 8 mm BC screw (p = 0.0079) and the 9 mm BC screw (p = 0.0079). Statistically significant differences between the 8 mm and the 9 mm BC screw could not be found (p = 0.15). During screwing into the tibial graft channel of the porcine specimens, insertion torques between 0.5 Nm and 3.2 Nm were recorded. In one case the hexagon head of a BC screw broke off during the last turn. Conclusions The BC screws show comparable torsional stability to Tutofix® interference screws. As expected the torsional strength of the screws increases significantly with the diameter. The safety and in vivo performance of products derived from xenogeneic bone should be the focus of further investigations. PMID:20433761

  10. Association of brain metabolism with sulcation and corpus callosum development assessed by MRI in late-onset small fetuses.

    PubMed

    Sanz-Cortes, Magdalena; Egaña-Ugrinovic, Gabriela; Simoes, Rui V; Vazquez, Lucia; Bargallo, Nuria; Gratacos, Eduard

    2015-06-01

    We sought to determine the relationship between fetal brain metabolism and microstructure expressed by brain sulcation, and corpus callosum (CC) development assessed by fetal brain magnetic resonance (MR) imaging and proton MR spectroscopy ((1)H-MRS). A total of 119 fetuses, 64 that were small for gestational age (estimated fetal weight <10th centile and normal umbilical artery Doppler) and 55 controls underwent a 3T MR imaging/(1)H-MRS exam at 37 weeks. Anatomical T2-weighted images were obtained in the 3 orthogonal planes and long echo time (TE) (1)H-MRS acquired from the frontal lobe. Head biometrics, cortical fissure depths (insula, Sylvian, parietooccipital, cingulate, and calcarine), and CC area and biometries were blindly performed by manual and semiautomated delineation using Analyze software and corrected creating ratios for biparietal diameter and frontooccipital diameter, respectively, for group comparison. Spectroscopic data were processed using LCModel software and analyzed as metabolic ratios of N-acetylaspartate (NAA) to choline (Cho), Cho to creatine (Cr), and myo-inositol (Ino) to Cho. Differences between cases and controls were assessed. To test for the association between metabolic ratios and microstructural parameters, bivariate correlation analyses were performed. Spectroscopic findings showed decreased NAA/Cho and increased Cho/Cr ratios in small fetuses. They also presented smaller head biometrics, shorter and smaller CC, and greater insular and cingulate depths. Frontal lobe NAA/Cho significantly correlated with biparietal diameter (r = 0.268; P = .021), head circumference (r = 0.259; P = .026), CC length (r = 0.265; P = .026), CC area (r = 0.317; P = .007), and the area of 6 from the 7 CC subdivisions. It did not correlate with any of the cortical sulcation parameters evaluated. None of the other metabolic ratios presented significant correlations with cortical development or CC parameters. Frontal lobe NAA/Cho levels-which are considered a surrogate marker of neuronal activity-show a strong association with CC development. These results suggest that both metabolic and callosal alterations may be part of the same process of impaired brain development associated with intrauterine growth restriction. Copyright © 2015 Elsevier Inc. All rights reserved.

  11. Comparative analysis of anchorage systems for micro implant orthodontics.

    PubMed

    Favero, Lorenzo; Giagnorio, Costantino; Cocilovo, Francesco

    2010-01-01

    The study analysed twelve anchorage systems based on micro implants in terms of their bio-mechanical properties and appraised their actual clinical effectiveness. The analysed micro implants had data provided by the manufacturers or extracted from articles published in specialised journals. The parameters taken into account were: material, surface treatment, head type, length, diameter, neck length, filleted self drilling or self tapping surface, applicable orthodontic forces, possibility of immediate loading, and device removal. Material Grade 5 titanium, titanium alloy (TiAl6V4), surgical steel; surfaces: smooth, sand-blasted and acid etched; head type: bracket, conic with button, round, hexagonal, button with cross cuts, double melted sphere; lengths: between 8.0 to 14 mm; diameters: between 1.2 to 2.0 mms; neck lengths: inferior to 1.5mm and superior to 2.0mm; filleted portion: self tapping and/or self drilling; applicable orthodontic forces: up to 500 g, possibility of immediate loading, device removal, possibility to use in growing patients. The most widely used material was TiAl6V4; most of the surfaces were smooth; the most commonly used head type was the bracket; the most often produced length was the "short" one (8.0-9.9 mm), the most demanded diameter the "smaller" one (1.2-1.4 mms); six systems out of eleven had micro implants with "extra" and "standard" necks; only 3 systems out of eleven produced "non self drilling"devices; all the micro implants analysed were able to withstand orthodontic forces between 150 g and 350 g; all devices were suitable for "immediate loading"; all micro implants had to be removed; all micro implants could be used in growing patients. The comparative analysis showed that micro implants could be used as valid anchorage systems, if dental anchorage was insufficient either in qualitative terms (i.e. parodontal problems) or in quantitative terms (i.e. few dental elements remaining), and in all those situations of limited patient compliance. Copyright © 2010 Società Italiana di Ortodonzia SIDO. Published by Elsevier Srl. All rights reserved.

  12. Parameters of thermochemical plumes responsible for the formation of batholiths: Results of experimental simulation

    NASA Astrophysics Data System (ADS)

    Kirdyashkin, A. A.; Kirdyashkin, A. G.; Gurov, V. V.

    2017-07-01

    Based on laboratory and theoretical modeling results, we present the thermal and hydrodynamical structure of the plume conduit during plume ascent and eruption on the Earth's surface. The modeling results show that a mushroom-shaped plume head forms after melt eruption on the surface for 1.9 < Ka < 10. Such plumes can be responsible for the formation of large intrusive bodies, including batholiths. The results of laboratory modeling of plumes with mushroom-shaped heads are presented for Ka = 8.7 for a constant viscosity and uniform melt composition. Images of flow patterns are obtained, as well as flow velocity profiles in the melt of the conduit and the head of the model plume. Based on the laboratory modeling data, we present a scheme of a thermochemical plume with a mushroom-shaped head responsible for the formation of a large intrusive body (batholith). After plume eruption to the surface, melting occurs along the base of the massif above the plume head, resulting in a mushroom-shaped plume head. A possible mechanism for the formation of localized surface manifestations of batholiths is presented. The parameters of some plumes with mushroom-shaped heads (plumes of the Altay-Sayan and Barguzin-Vitim large-igneous provinces, and Khangai and Khentei plumes) are estimated using geological data, including age intervals and volumes of magma melts.

  13. Effects of implant design parameters on fluid convection, potentiating third-body debris ingress into the bearing surface during THA impingement/subluxation.

    PubMed

    Lundberg, Hannah J; Pedersen, Douglas R; Baer, Thomas E; Muste, Marian; Callaghan, John J; Brown, Thomas D

    2007-01-01

    Aseptic loosening from polyethylene wear debris is the leading cause of failure for metal-on-polyethylene total hip implants. Third-body debris ingress to the bearing space results in femoral head roughening and acceleration of polyethylene wear. How third-body particles manage to enter the bearing space between the closely conforming articulating surfaces of the joint is not well understood. We hypothesize that one such mechanism is from convective fluid transport during subluxation of the total hip joint. To test this hypothesis, a three-dimensional (3D) computational fluid dynamics (CFD) model was developed and validated, to quantify fluid ingress into the bearing space during a leg-cross subluxation event. The results indicated that extra-articular joint fluid could be drawn nearly to the pole of the cup with even very small separations of the femoral head (<0.60mm). Debris suspended near the equator of the cup at the site of maximum fluid velocity just before the subluxation began could be transported to within 11 degrees from the cup pole. Larger head diameters resulted in increased fluid velocity at all sites around the entrance to the gap compared to smaller head sizes, with fluid velocity being greatest along the anterosuperolateral cup edge, for all head sizes. Fluid pathlines indicated that suspended debris would reach similar angular positions in the bearing space regardless of head size. Increased inset of the femoral head into the acetabular cup resulted both in higher fluid velocity and in transport of third-body debris further into the bearing space.

  14. Brush head composition, wear profile, and cleaning efficacy: an assessment of three electric brush heads using in vitro methods.

    PubMed

    Kaiser, Eva; Meyners, Michael; Markgraf, Dirk; Stoerkel, Ulrich; von Koppenfels, Roxana; Adam, Ralf; Soukup, Martin; Wehrbein, Heinrich; Erbe, Christina

    2014-01-01

    The objective of this research was to evaluate a current store brand (SB) brush head for composition/physical characteristics, Wear Index (WI), and cleaning efficacy versus the previous SB brush head refill design (SB control) and the Oral-B Precision Clean brush head (positive control, PC). This research consisted of three parts: 1) Analytical analysis using Fourier Transform Infrared (FT-IR) spectrometry to evaluate the chemical composition of the current SB brush head bristles relative to the SB control. In addition, physical parameters such as bristle count and diameter were determined. 2) Wear Index (WI) investigation to determine the Wear Index scores of in vitro-aged brush heads at four weeks (one month) and 13 weeks (three months) by a trained investigator. To "age" the brush heads, a robot system was used as a new alternative in vitro method to simulate aging by consumer use. 3) Robot testing to determine the cleaning performance of in vitro-aged brush heads, comparing one month-aged current SB brush heads with the SB control (one and three months-aged) and the PC brush heads (three months-aged) in a standardized fashion. 1) FT-IR analysis revealed that the chemical composition of the current and control SB refill brush heads is identical. In terms of physical parameters, the current SB brush head has 12% more bristles and a slightly oval brush head compared to the round brush head of the SB control. 2) Wear Index analysis showed there was no difference in the one month-aged current SB brush head versus the one month-aged SB control (1.67 vs. 1.50, p = 0.65) or versus the three months-aged PC brush head (1.67 vs. 1.50, p = 0.65). The one month-aged current SB brush head demonstrated statistically significantly less wear than the three months-aged SB control (1.67 vs. 2.67, p = 0.01). 3) Analysis of cleaning efficacy shows that the one month-aged current SB brush head had improved cleaning performance over the one month-aged SB control brush head (p < 0.05), despite no statistically significant difference in wear. Both the one month-aged current and control SB brush heads showed statistically significantly lower cleaning performance compared to the three months-aged PC brush heads (p < 0.01). While the current SB brush head showed improved cleaning over the SB control, it demonstrated significantly lower durability and cleaning in comparison to the PC brush head. Dental professionals should be aware of these differences, both in durability and in cleaning performance, when recommending brush heads to their patients.

  15. Load-bearing Characters Analysis of Large Diameter Rock-Socketed Filling Piles Based on Self-Balanced Method

    NASA Astrophysics Data System (ADS)

    tongqing, Wu; liang, Li; xinjian, Liu; Xu, nianchun; Tian, Mao

    2018-03-01

    Self-balanced method is carried out on the large diameter rock-socketed filling piles of high-pile wharf at Inland River, to explore the distribution laws of load-displacement curve, pile internal force, pile tip friction resistance and pile side friction resistance under load force. The results showed that: the tip resistance of S1 and S2 test piles accounted for 53.4% and 53.6% of the pile bearing capacity, respectively, while the total side friction resistance accounted for 46.6% and 46.4% of the pile bearing capacity, respectively; both the pile tip friction resistance and pile side friction resistance can be fully played, and reach to the design requirements. The reasonability of large diameter rock-socketed filling design is verified through test analysis, which can provide basis for the optimization of high-pile wharf structural type, thus reducing the wharf project cost, and also providing reference for the similar large diameter rock-socketed filling piles of high-pile wharf at Inland River.

  16. A pressure-packer system for conducting rising head tests in water table wells

    USGS Publications Warehouse

    Levy, Benjamin S.; Pannell, Lawrence J.; Dadoly, John P.

    1993-01-01

    The pressure system developed for fully-saturated well screens has been modified for conducting rising head tests in water table wells installed in highly permeable aquifers. The pressure system consists of a compressed air source and 1 inch diameter PVC piping with a packer attached at the end. The pressure system was evaluated in a series of rising head tests conducted in a well at a Superfund site in New England. The well was tested with slugs and with the pressure system. Within each technique, estimates of hydraulic conductivity showed no difference. Comparison of hydraulic conductivity estimates between techniques (slug test vs. pressure test) showed differences due to stratigraphy. The interval tested using slug tests crossed two stratigraphic units; the pressure system tested only one of these units. We conclude that the pressure system may be used to characterize the vertical hydraulic conductivity distribution in a series of successive tests by changing the packer position and the screened interval tested.

  17. Effects of Shell-Buckling Knockdown Factors in Large Cylindrical Shells

    NASA Technical Reports Server (NTRS)

    Hrinda, Glenn A.

    2012-01-01

    Shell-buckling knockdown factors (SBKF) have been used in large cylindrical shell structures to account for uncertainty in buckling loads. As the diameter of the cylinder increases, achieving the manufacturing tolerances becomes increasingly more difficult. Knockdown factors account for manufacturing imperfections in the shell geometry by decreasing the allowable buckling load of the cylinder. In this paper, large-diameter (33 ft) cylinders are investigated by using various SBKF's. An investigation that is based on finite-element analysis (FEA) is used to develop design sensitivity relationships. Different manufacturing imperfections are modeled into a perfect cylinder to investigate the effects of these imperfections on buckling. The analysis results may be applicable to large- diameter rockets, cylindrical tower structures, bulk storage tanks, and silos.

  18. Learning-based scan plane identification from fetal head ultrasound images

    NASA Astrophysics Data System (ADS)

    Liu, Xiaoming; Annangi, Pavan; Gupta, Mithun; Yu, Bing; Padfield, Dirk; Banerjee, Jyotirmoy; Krishnan, Kajoli

    2012-03-01

    Acquisition of a clinically acceptable scan plane is a pre-requisite for ultrasonic measurement of anatomical features from B-mode images. In obstetric ultrasound, measurement of gestational age predictors, such as biparietal diameter and head circumference, is performed at the level of the thalami and cavum septum pelucidi. In an accurate scan plane, the head can be modeled as an ellipse, the thalami looks like a butterfly, the cavum appears like an empty box and the falx is a straight line along the major axis of a symmetric ellipse inclined either parallel to or at small angles to the probe surface. Arriving at the correct probe placement on the mother's belly to obtain an accurate scan plane is a task of considerable challenge especially for a new user of ultrasound. In this work, we present a novel automated learning-based algorithm to identify an acceptable fetal head scan plane. We divide the problem into cranium detection and a template matching to capture the composite "butterfly" structure present inside the head, which mimics the visual cues used by an expert. The algorithm uses the stateof- the-art Active Appearance Models techniques from the image processing and computer vision literature and tie them to presence or absence of the inclusions within the head to automatically compute a score to represent the goodness of a scan plane. This automated technique can be potentially used to train and aid new users of ultrasound.

  19. A new static sampler for airborne total dust in workplaces.

    PubMed

    Mark, D; Vincent, J H; Gibson, H; Lynch, G

    1985-03-01

    This paper describes the development and laboratory testing of a new static dust sampler for airborne total dust in workplaces. Particular attention is paid to designing the sampling head and entry consistent with the concept of inspirability which in turn defines a biologically-relevant aspiration efficiency. The sampling head has a small cylindrical body and a transverse entry slot with thin protruding lips forming an integral part of a weighable capsule containing a 37 mm filter which collects all of the sampled dust (without introducing errors due to external particle blow-off or internal wall losses). A battery-powered sampling pump provides both air suction at 3 L/min and rigid mounting for the sampling head. The sampling head is rotated continuously through 360 degrees at approximately 1.5 rpm by a simple electric drive, connected to the stationary pump through a rotating seal. Wind tunnel testing of the instrument showed it to display an entry efficiency very close to the inspirability curve of Vincent and Armbruster (now recommended by the ACGIH Technical Committee on Air Sampling Procedures for defining inspirable particulate matter (IPM] for particles of aerodynamic diameter up to 90 micron and for windspeeds in the range of one to three m/sec.

  20. Development of a fiber based Raman probe compatible with interventional magnetic resonance imaging

    NASA Astrophysics Data System (ADS)

    Ashok, Praveen C.; Praveen, Bavishna B.; Rube, Martin; Cox, Benjamin; Melzer, Andreas; Dholakia, Kishan

    2014-02-01

    Raman spectroscopy has proven to be a powerful tool for discriminating between normal and abnormal tissue types. Fiber based Raman probes have demonstrated its potential for in vivo disease diagnostics. Combining Raman spectroscopy with Magnetic Resonance Imaging (MRI) opens up new avenues for MR guided minimally invasive optical biopsy. Although Raman probes are commercially available, they are not compatible with a MRI environment due to the metallic components which are used to align the micro-optic components such as filters and lenses at the probe head. Additionally they are not mechanically compatible with a typical surgical environment as factors such as sterility and length of the probe are not addressed in those designs. We have developed an MRI compatible fiber Raman probe with a disposable probe head hence maintaining sterility. The probe head was specially designed to avoid any material that would cause MR imaging artefacts. The probe head that goes into patient's body had a diameter <1.5 mm so that it is compatible with biopsy needles and catheters. The probe has been tested in MR environment and has been proven to be capable of obtaining Raman signal while the probe is under real-time MR guidance.

  1. Spirosymplokos deltaeiberi nov. gen., nov. sp.: variable-diameter composite spirochete from microbial mats

    NASA Technical Reports Server (NTRS)

    Guerrero, R.; Ashen, J.; Sole, M.; Margulis, L.

    1993-01-01

    Large (up to 100 micrometers long), loosely coiled, free-living spirochetes with variable diameters (from 0.4 to 3 micrometers in the same cell) were seen at least 40 times between August 1990 and January 1993. These spirochetes were observed in mud water and enrichment media from highly specific habitats in intertidal evaporite flats at three disjunct localities, one in Spain and two in Mexico. All three are sites of commercial saltworks. Associated with Microcoleus chthonoplastes the large spirochetes from Spain display phototaxis and a composite organization. Shorter and smaller-diameter spirochetes are seen inside both healthy and spent periplasm of larger ones. Small spirochetes attached to large ones have been observed live. From two to twelve spirochete protoplasmic cylinders were seen inside a single common outer membrane. A distinctive granulated cytoplasm in which the granules are of similar diameter (20-32 nanometers) to that of the flagella (26 nanometers) was present. Granule diameters were measured in thin section and in negatively-stained whole-mount preparations. Based on their ultrastructure, large size, variable diameter, number of flagella (3 to 6), and phototactic behavior these unique spirochetes are formally named Spirosymplokos deltaeiberi. Under anoxic (or low oxygen) conditions they formed blooms in mixed culture in media selective for spirochetes. Cellobiose was the major carbon source in 80% seawater, the antibiotic rifampicin was added, mat from the original field site was present and tubes were incubated in the light at from 18-31 degrees C. Within 1-2 weeks populations of the large spirochete developed at 25 degrees C but they could not be transferred to fresh medium.

  2. Spatiotopic coding during dynamic head tilt

    PubMed Central

    Turi, Marco; Burr, David C.

    2016-01-01

    Humans maintain a stable representation of the visual world effortlessly, despite constant movements of the eyes, head, and body, across multiple planes. Whereas visual stability in the face of saccadic eye movements has been intensely researched, fewer studies have investigated retinal image transformations induced by head movements, especially in the frontal plane. Unlike head rotations in the horizontal and sagittal planes, tilting the head in the frontal plane is only partially counteracted by torsional eye movements and consequently induces a distortion of the retinal image to which we seem to be completely oblivious. One possible mechanism aiding perceptual stability is an active reconstruction of a spatiotopic map of the visual world, anchored in allocentric coordinates. To explore this possibility, we measured the positional motion aftereffect (PMAE; the apparent change in position after adaptation to motion) with head tilts of ∼42° between adaptation and test (to dissociate retinal from allocentric coordinates). The aftereffect was shown to have both a retinotopic and spatiotopic component. When tested with unpatterned Gaussian blobs rather than sinusoidal grating stimuli, the retinotopic component was greatly reduced, whereas the spatiotopic component remained. The results suggest that perceptual stability may be maintained at least partially through mechanisms involving spatiotopic coding. NEW & NOTEWORTHY Given that spatiotopic coding could play a key role in maintaining visual stability, we look for evidence of spatiotopic coding after retinal image transformations caused by head tilt. To this end, we measure the strength of the positional motion aftereffect (PMAE; previously shown to be largely spatiotopic after saccades) after large head tilts. We find that, as with eye movements, the spatial selectivity of the PMAE has a large spatiotopic component after head rotation. PMID:27903636

  3. Estimating the Effects of Head Start on Parenting and Child Maltreatment

    PubMed Central

    Waldfogel, Jane; Brooks-Gunn, Jeanne

    2011-01-01

    We examine the effects of Head Start participation on parenting and child maltreatment in a large and diverse sample of low-income families in large U.S. cities (N = 2,807), using rich data from the Fragile Families and Child Wellbeing Study (FFCWS). To address the issue of selection bias, we employ several analytic approaches, including logistic regressions with a rich set of pretreatment controls as well as propensity score matching models, comparing the effects of Head Start to any other arrangements as well as specific types of other arrangements. We find that compared to children who did not attend Head Start, children who did attend Head Start are less likely to have low access to learning materials and less likely to experience spanking by their parents at age five. Moreover, we find that the effects of Head Start vary depending on the specific type of other child care arrangements to which they are compared, with the most consistently beneficial protective effects seen when Head Start is compared to being home in exclusively parental care. PMID:23788823

  4. Chronic cervical radiculopathic pain is associated with increased excitability and hyperpolarization-activated current ( Ih) in large-diameter dorsal root ganglion neurons.

    PubMed

    Liu, Da-Lu; Wang, Xu; Chu, Wen-Guang; Lu, Na; Han, Wen-Juan; Du, Yi-Kang; Hu, San-Jue; Bai, Zhan-Tao; Wu, Sheng-Xi; Xie, Rou-Gang; Luo, Ceng

    2017-01-01

    Cervical radiculopathic pain is a very common symptom that may occur with cervical spondylosis. Mechanical allodynia is often associated with cervical radiculopathic pain and is inadequately treated with current therapies. However, the precise mechanisms underlying cervical radiculopathic pain-associated mechanical allodynia have remained elusive. Compelling evidence from animal models suggests a role of large-diameter dorsal root ganglion neurons and plasticity of spinal circuitry attached with Aβ fibers in mediating neuropathic pain. Whether cervical radiculopathic pain condition induces plastic changes of large-diameter dorsal root ganglion neurons and what mechanisms underlie these changes are yet to be known. With combination of patch-clamp recording, immunohistochemical staining, as well as behavioral surveys, we demonstrated that upon chronic compression of C7/8 dorsal root ganglions, large-diameter cervical dorsal root ganglion neurons exhibited frequent spontaneous firing together with hyperexcitability. Quantitative analysis of hyperpolarization-activated cation current ( I h ) revealed that I h was greatly upregulated in large dorsal root ganglion neurons from cervical radiculopathic pain rats. This increased I h was supported by the enhanced expression of hyperpolarization-activated, cyclic nucleotide-modulated channels subunit 3 in large dorsal root ganglion neurons. Blockade of I h with selective antagonist, ZD7288 was able to eliminate the mechanical allodynia associated with cervical radiculopathic pain. This study sheds new light on the functional plasticity of a specific subset of large-diameter dorsal root ganglion neurons and reveals a novel mechanism that could underlie the mechanical allodynia associated with cervical radiculopathy.

  5. 75 FR 14243 - Pipeline Safety: Girth Weld Quality Issues Due to Improper Transitioning, Misalignment, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-24

    ... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket No..., and Welding Practices of Large Diameter Line Pipe AGENCY: Pipeline and Hazardous Materials Safety... bulletin to notify owners and operators of recently constructed large diameter natural gas pipeline and...

  6. Addition of lysophospholipids with large head groups to cells inhibits Shiga toxin binding.

    PubMed

    Ailte, Ieva; Lingelem, Anne Berit Dyve; Kavaliauskiene, Simona; Bergan, Jonas; Kvalvaag, Audun Sverre; Myrann, Anne-Grethe; Skotland, Tore; Sandvig, Kirsten

    2016-07-26

    Shiga toxin (Stx), an AB5 toxin, binds specifically to the neutral glycosphingolipid Gb3 at the cell surface before being transported into cells. We here demonstrate that addition of conical lysophospholipids (LPLs) with large head groups inhibit Stx binding to cells whereas LPLs with small head groups do not. Lysophosphatidylinositol (LPI 18:0), the most efficient LPL with the largest head group, was selected for in-depth investigations to study how the binding of Stx is regulated. We show that the inhibition of Stx binding by LPI is reversible and possibly regulated by cholesterol since addition of methyl-β-cyclodextrin (mβCD) reversed the ability of LPI to inhibit binding. LPI-induced inhibition of Stx binding is independent of signalling and membrane turnover as it occurs in fixed cells as well as after depletion of cellular ATP. Furthermore, data obtained with fluorescent membrane dyes suggest that LPI treatment has a direct effect on plasma membrane lipid packing with shift towards a liquid disordered phase in the outer leaflet, while lysophosphoethanolamine (LPE), which has a small head group, does not. In conclusion, our data show that cellular treatment with conical LPLs with large head groups changes intrinsic properties of the plasma membrane and modulates Stx binding to Gb3.

  7. Assessment of present state-of-the-art sawing technology of large diameter ingots for solar sheet material

    NASA Technical Reports Server (NTRS)

    Yoo, H. I.

    1977-01-01

    The objective of this program is to assess the present state-of-the-art sawing technology of large diameter silicon ingots (3 inch and 4 inch diameter) for solar sheet materials. During this period, work has progressed in three areas: (1) slicing of the ingots with the multiblade slurry saw and the I.D. saw, (2) characterization of the sliced wafers, and (3) analysis of direct labor, expendable material costs, and wafer productivity.

  8. Large scale study on the variation of RF energy absorption in the head & brain regions of adults and children and evaluation of the SAM phantom conservativeness.

    PubMed

    Keshvari, J; Kivento, M; Christ, A; Bit-Babik, G

    2016-04-21

    This paper presents the results of two computational large scale studies using highly realistic exposure scenarios, MRI based human head and hand models, and two mobile phone models. The objectives are (i) to study the relevance of age when people are exposed to RF by comparing adult and child heads and (ii) to analyze and discuss the conservativeness of the SAM phantom for all age groups. Representative use conditions were simulated using detailed CAD models of two mobile phones operating between 900 MHz and 1950 MHz including configurations with the hand holding the phone, which were not considered in most previous studies. The peak spatial-average specific absorption rate (psSAR) in the head and the pinna tissues is assessed using anatomically accurate head and hand models. The first of the two mentioned studies involved nine head-, four hand- and two phone-models, the second study included six head-, four hand- and three simplified phone-models (over 400 configurations in total). In addition, both studies also evaluated the exposure using the SAM phantom. Results show no systematic differences between psSAR induced in the adult and child heads. The exposure level and its variation for different age groups may be different for particular phones, but no correlation between psSAR and model age was found. The psSAR from all exposure conditions was compared to the corresponding configurations using SAM, which was found to be conservative in the large majority of cases.

  9. Large scale study on the variation of RF energy absorption in the head & brain regions of adults and children and evaluation of the SAM phantom conservativeness

    NASA Astrophysics Data System (ADS)

    Keshvari, J.; Kivento, M.; Christ, A.; Bit-Babik, G.

    2016-04-01

    This paper presents the results of two computational large scale studies using highly realistic exposure scenarios, MRI based human head and hand models, and two mobile phone models. The objectives are (i) to study the relevance of age when people are exposed to RF by comparing adult and child heads and (ii) to analyze and discuss the conservativeness of the SAM phantom for all age groups. Representative use conditions were simulated using detailed CAD models of two mobile phones operating between 900 MHz and 1950 MHz including configurations with the hand holding the phone, which were not considered in most previous studies. The peak spatial-average specific absorption rate (psSAR) in the head and the pinna tissues is assessed using anatomically accurate head and hand models. The first of the two mentioned studies involved nine head-, four hand- and two phone-models, the second study included six head-, four hand- and three simplified phone-models (over 400 configurations in total). In addition, both studies also evaluated the exposure using the SAM phantom. Results show no systematic differences between psSAR induced in the adult and child heads. The exposure level and its variation for different age groups may be different for particular phones, but no correlation between psSAR and model age was found. The psSAR from all exposure conditions was compared to the corresponding configurations using SAM, which was found to be conservative in the large majority of cases.

  10. Estimation of body mass index from the metrics of the first metatarsal

    NASA Astrophysics Data System (ADS)

    Dunn, Tyler E.

    Estimation of the biological profile from as many skeletal elements as possible is a necessity in both forensic and bioarchaeological contexts; this includes non-standard aspects of the biological profile, such as body mass index (BMI). BMI is a measure that allows for understanding of the composition of an individual and is traditionally divided into four groups: underweight, normal weight, overweight, and obese. BMI estimation incorporates both estimation of stature and body mass. The estimation of stature from skeletal elements is commonly included into the standard biological profile but the estimation of body mass needs to be further statistically validated to be consistently included. The bones of the foot, specifically the first metatarsal, may have the ability to estimate BMI given an allometric relationship to stature and the mechanical relationship to body mass. There are two commonly used methods for stature estimation, the anatomical method and the regression method. The anatomical method takes into account all of the skeletal elements that contribute to stature while the regression method relies on the allometric relationship between a skeletal element and living stature. A correlation between the metrics of the first metatarsal and living stature has been observed, and proposed as a method for valid stature estimation from the boney foot (Byers et al., 1989). Body mass estimation from skeletal elements relies on two theoretical frameworks: the morphometric and the mechanical approaches. The morphometric approach relies on the size relationship of the individual to body mass; the basic relationship between volume, density, and weight allows for body mass estimation. The body is thought of as a cylinder, and in order to understand the volume of this cylinder the diameter is needed. A commonly used proxy for this in the human body is skeletal bi-iliac breadth from rearticulated pelvic girdle. The mechanical method of body mass estimation relies on the ideas of biomechanical bone remodeling; the elements of the skeleton that are under higher forces, including weight, will remodel to minimize stress. A commonly used metric for the mechanical method of body mass estimation is the diameter of the head of the femur. The foot experiences nearly the entire weight force of the individual at any point in the gait cycle and is subject to the biomechanical remodeling that this force would induce. Therefore, the application of the mechanical framework for body mass estimation could stand true for the elements of the foot. The morphometric and mechanical approaches have been validated against one another on a large, geographically disparate population (Auerbach and Ruff, 2004), but have yet to be validated on a sample of known body mass. DeGroote and Humphrey (2011) test the ability of the first metatarsal to estimate femoral head diameter, body mass, and femoral length. The estimated femoral head diameter from the first metatarsal is used to estimate body mass via the morphometric approach and the femoral length is used to estimate living stature. The authors find that body mass and stature estimation methods from more commonly used skeletal elements compared well with the methods developed from the first metatarsal. This study examines 388 `White' individuals from the William M. Bass donated skeletal collection to test the reliability of the body mass estimates from femoral head diameter and bi-iliac breadth, stature from maximum femoral length, and body mass and stature from the metrics of the first metatarsal. This sample included individuals from all four of the BMI classes. This study finds that all of the skeletal indicators compare well with one another; there is no statistical difference in the stature estimates from the first metatarsal and the maximum length of the femur, and there is no statistical between all three of the body mass estimation methods. When compared to the forensic estimates of stature neither of the tested methods had statistical difference. Conversely, when the body mass estimates are compared to forensic body mass there was a statistical difference and when further investigated the most difference in the body mass estimates was in the extremes of body mass (the underweight and obese categories). These findings indicate that the estimation of stature from both the maximum femoral length and the metrics of the metatarsal are accurate methods. Furthermore, the estimation of body mass is accurate when the individual is in the middle range of the BMI spectrum while these methods for outlying individuals are inaccurate. These findings have implications for the application of stature and body mass estimation in the fields of bioarchaeology, forensic anthropology, and paleoanthropology.

  11. Spermatogenesis in Animals as Revealed by Electron Microscopy

    PubMed Central

    Yasuzumi, G.; Tanaka, Hiroaki

    1958-01-01

    This paper reports an electron microscope study of typical and atypical spermatogenesis in the pond snail, Cipangopaludina malteata. In the typical spermatid the nucleus undergoes profound changes as development proceeds, affecting both its form and internal fine structure. A large number of roughly parallel, dense filaments, arranged along the long axis of the nucleus, fuse with each other to form in the end the homogeneous helical body characteristic of the head of the adult spermatozoa. The nebenkern is apparently mitochondrial in nature and, in its early development, is similar to that of insects except that it appears as a double structure from the beginning. As differentiation proceeds, the mitochondria lose their membranes, and the residual, now denuded cristae, reorganize to give a parallel radial arrangement. In the last stages of development, the nebenkern derivations become applied to the sheath of the middle piece in a compact helical fashion. In the development of the atypical spermatozoa, the nucleus fails to differentiate and simply shrinks in volume until only a remnant, devoid of DNA, is left. The cytoplasm shows numerous vesicles containing small Feulgen-positive bodies, 80 to 130 mµ in diameter. These vesicles plus contents increase in number as spermatogenesis proceeds. The "head" structure of the atypical spermatozoa consists of a bundle (7 to 17) of tail flagella, each with a centriole at its anterior end. The end-piece of the atypical form appears brush-like and is made up of the free ends of the several flagella. PMID:13587559

  12. An empirical model of human aspiration in low-velocity air using CFD investigations.

    PubMed

    Anthony, T Renée; Anderson, Kimberly R

    2015-01-01

    Computational fluid dynamics (CFD) modeling was performed to investigate the aspiration efficiency of the human head in low velocities to examine whether the current inhaled particulate mass (IPM) sampling criterion matches the aspiration efficiency of an inhaling human in airflows common to worker exposures. Data from both mouth and nose inhalation, averaged to assess omnidirectional aspiration efficiencies, were compiled and used to generate a unifying model to relate particle size to aspiration efficiency of the human head. Multiple linear regression was used to generate an empirical model to estimate human aspiration efficiency and included particle size as well as breathing and freestream velocities as dependent variables. A new set of simulated mouth and nose breathing aspiration efficiencies was generated and used to test the fit of empirical models. Further, empirical relationships between test conditions and CFD estimates of aspiration were compared to experimental data from mannequin studies, including both calm-air and ultra-low velocity experiments. While a linear relationship between particle size and aspiration is reported in calm air studies, the CFD simulations identified a more reasonable fit using the square of particle aerodynamic diameter, which better addressed the shape of the efficiency curve's decline toward zero for large particles. The ultimate goal of this work was to develop an empirical model that incorporates real-world variations in critical factors associated with particle aspiration to inform low-velocity modifications to the inhalable particle sampling criterion.

  13. Preliminary Engineering Study of Long-Lead Time Equipment Required for Large Lightweight Mirror Manufacture

    DTIC Science & Technology

    1981-06-01

    numnber) Annealing Fusion Sealed Mirrors ULED Mirrors Boule Large Lightweight Mirror Core Low Expansion Glass Coremaker Mirror Blanks Forming Furnace...Experiments 34 4 10.6 Grinder Procurement 35 J 1 I GLOSSARY Alpha - Coef. of thermal expansion. Boule - The disc of glass formed in the furnace. Cell...turning over of large plates, cores or mirrors. Flowout - Method used to produce large diameter plates from small diameter boules. Glass - Used in the

  14. 77 FR 24462 - Certain Steel Nails From the People's Republic of China: Amended Final Results of the Second...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-24

    ... steel nails: (1) Non-collated (i.e., hand-driven or bulk), two-piece steel nails having plastic or steel...-collated (i.e., hand-driven or bulk), steel nails having a bright or galvanized finish, a smooth, barbed or... actual head diameter of 0.3375'' to 0.500'', inclusive; and (4) Non-collated (i.e., hand-driven or bulk...

  15. A novel tribological study on DLC-coated micro-dimpled orthopedics implant interface.

    PubMed

    Choudhury, Dipankar; Urban, Filip; Vrbka, Martin; Hartl, Martin; Krupka, Ivan

    2015-05-01

    This study investigates a tribological performance of diamond like carbon (DLC) coated micro dimpled prosthesis heads against ceramic cups in a novel pendulum hip joint simulator. The simulator enables determining friction coefficient and viscous effects of a concave shaped specimen interface (conformal contact). Two types of DLC such as hydrogenated amorphous carbon (a-C:H) and tetrahedral amorphous carbon (Ta-C) and one set of micro dimple (diameter of 300µm, depth of 70µm, and pitch of 900µm) were fabricated on metallic prosthesis heads. The experiment results reveal a significant friction coefficient reduction to the 'dimpled a-C:H/ceramic' prosthesis compared to a 'Metal (CoCr)/ceramic' prosthesis because of their improved material and surface properties and viscous effect. The post-experiment surface analysis displays that the dimpled a-C:H yielded a minor change in the surface roughness, and generated a larger sizes of wear debris (40-200nm sized, equivalent diameter), a size which could be certainly stored in the dimple, thus likely to reducing their possible third body abrasive wear rate. Thus, dimpled a:C-H can be used as a 'metal on ceramic hip joint interface', whereas the simulator can be utilized as an advanced bio-tribometer. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. Diamond-anvil high-pressure cell with improved X-ray collimation system

    DOEpatents

    Schiferl, David; Olinger, Barton W.; Livingston, Robert W.

    1986-01-01

    An adjustable X-ray collimation system for a diamond-anvil high-pressure cell of the type including a cooperable piston and cylinder and a pair of opposing diamonds located between the head of the piston and the head of the cylinder. The X-ray collimation system includes a tubular insert which contains an X-ray collimator. The insert is engageable in the bore of the piston. The collimator is mounted within the insert by means of an elastomeric O-ring at the end closest the opposed diamonds, and by means of a set of adjustable set screws at the opposite end. By adjustment of the set screws the collimator can be pivoted about the O-ring and brought into alignment with the opposed diamonds and the sample contained therein. In the preferred embodiment there is further provided a set of plugs which are insertable in the bore of the collimator. The plugs have bores of different diameters. By successively inserting plugs of progressively smaller bore diameters and adjusting the alignment of the collimator with each plug, the collimator can be quickly brought into accurate alignment with the diamonds. The collimation system allows alignment of the collimator either before or after the cell has been loaded and pressurized.

  17. Five-Hole Flow Angle Probe Calibration for the NASA Glenn Icing Research Tunnel

    NASA Technical Reports Server (NTRS)

    Gonsalez, Jose C.; Arrington, E. Allen

    1999-01-01

    A spring 1997 test section calibration program is scheduled for the NASA Glenn Research Center Icing Research Tunnel following the installation of new water injecting spray bars. A set of new five-hole flow angle pressure probes was fabricated to properly calibrate the test section for total pressure, static pressure, and flow angle. The probes have nine pressure ports: five total pressure ports on a hemispherical head and four static pressure ports located 14.7 diameters downstream of the head. The probes were calibrated in the NASA Glenn 3.5-in.-diameter free-jet calibration facility. After completing calibration data acquisition for two probes, two data prediction models were evaluated. Prediction errors from a linear discrete model proved to be no worse than those from a full third-order multiple regression model. The linear discrete model only required calibration data acquisition according to an abridged test matrix, thus saving considerable time and financial resources over the multiple regression model that required calibration data acquisition according to a more extensive test matrix. Uncertainties in calibration coefficients and predicted values of flow angle, total pressure, static pressure. Mach number. and velocity were examined. These uncertainties consider the instrumentation that will be available in the Icing Research Tunnel for future test section calibration testing.

  18. Diamond-anvil high-pressure cell with improved x-ray collimation system

    DOEpatents

    Schiferl, D.; Olinger, B.W.; Livingston, R.W.

    1984-03-30

    An adjustable x-ray collimation system for a diamond-anvil high-pressure cell of the type including a cooperable piston and cylinder and a pair of opposing diamonds located between the head of the piston and the head of the cylinder. The x-ray collimation system includes a tubular insert which contains an x-ray collimator. The insert is engageable in the bore of the piston. The collimator is mounted within the insert by means of an elastomeric o-ring at the end closest the opposed diamonds, and by means of a set of adjustable set screws at the opposite end. By adjustment of the set screws the collimator can be pivoted about the o-ring and brought into alignment with the opposed diamonds and the sample contained therein. In the preferred embodiment there is further provided a set of plugs which are insertable in the bore of the collimator. The plugs have bores of different diameters. By successively inserting plugs of progressively smaller bore diameters and adjusting the alignment of the collimator with each plug, the collimator can be quickly brought into accurate alignment with the diamonds. The collimation system allows alignment of the collimator either before or after the cell has been loaded and pressurized.

  19. Isolation and characterization of T7-like lytic bacteriophages infecting multidrug resistant Pseudomonas aeruginosa isolated from Egypt.

    PubMed

    El Didamony, Gamal; Askora, Ahmed; Shehata, Aya A

    2015-06-01

    In this study, two lytic phages designated as ϕPSZ1 and ϕPSZ2 infecting multidrug resistant Pseudomonas aeruginosa were isolated from sewage samples collected in Zagazig, Egypt. Morphological analysis by transmission electron microscopy revealed that both phages belong to the podoviridae family and resembles typical T7-like phages. ϕPSZ1 has a head of about 60 ± 5 nm in diameter with a short tail of 19 ± 2 nm in length, while ϕPSZ2 has a head of about 57 ± 5 nm in diameter with a short tail of 14 ± 2 nm in length. Both phages were shown to be able to infect 13 different P. aeruginosa strains and has no effect on other tested bacteria. In spite of morphological similarity, these phages showed diverged genomic sequences revealed by restriction enzyme digestion analysis. One-step growth curves of bacteriophages revealed eclipse and latent periods of 12 min for ϕPSZ1 and 15 min for ϕPSZ2, respectively, with burst sizes of about 100 per infected cell. Phage treatment prevented the growth of P. aeruginosa for up to 18 h with multiplicity of infection ratios of 1. These results suggest that both phages have a high potential for phage application to control P. aeruginosa.

  20. Ella Flagg Young: Tribute to a Pioneer Leader in Education.

    ERIC Educational Resources Information Center

    Webb, L. Dean; McCarthy, Martha M.

    1996-01-01

    Young was the first woman to head a large city school system, the first woman to serve as head of a large teachers college, and the first woman president of the National Education Association. Her visionary accomplishments offer inspiration for current women administrators to continue in the quest to improve education. (LSR)

  1. Penguin head movement detected using small accelerometers: a proxy of prey encounter rate.

    PubMed

    Kokubun, Nobuo; Kim, Jeong-Hoon; Shin, Hyoung-Chul; Naito, Yasuhiko; Takahashi, Akinori

    2011-11-15

    Determining temporal and spatial variation in feeding rates is essential for understanding the relationship between habitat features and the foraging behavior of top predators. In this study we examined the utility of head movement as a proxy of prey encounter rates in medium-sized Antarctic penguins, under the presumption that the birds should move their heads actively when they encounter and peck prey. A field study of free-ranging chinstrap and gentoo penguins was conducted at King George Island, Antarctica. Head movement was recorded using small accelerometers attached to the head, with simultaneous monitoring for prey encounter or body angle. The main prey was Antarctic krill (>99% in wet mass) for both species. Penguin head movement coincided with a slow change in body angle during dives. Active head movements were extracted using a high-pass filter (5 Hz acceleration signals) and the remaining acceleration peaks (higher than a threshold acceleration of 1.0 g) were counted. The timing of head movements coincided well with images of prey taken from the back-mounted cameras: head movement was recorded within ±2.5 s of a prey image on 89.1±16.1% (N=7 trips) of images. The number of head movements varied largely among dive bouts, suggesting large temporal variations in prey encounter rates. Our results show that head movement is an effective proxy of prey encounter, and we suggest that the method will be widely applicable for a variety of predators.

  2. Wall-Friction Support of Vertical Loads in Submerged Sand and Gravel Columns

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Walton, O. R.; Vollmer, H. J.; Hepa, V. S.

    Laboratory studies of the ‘floor-loads’ under submerged vertical columns of sand and/or gravel indicate that such loads can be approximated by a buoyancy-corrected Janssen-silo-theory-like relationship. Similar to conditions in storage silos filled with dry granular solids, most of the weight of the sand or gravel is supported by wall friction forces. Laboratory measurements of the loads on the floor at the base of the water-filled columns (up to 25-diameters tall) indicate that the extra floor-load from the addition of the granular solid never exceeded the load that would exist under an unsupported (wide) bed of submerged sand or gravel thatmore » has a total depth corresponding to only two column-diameters. The measured floorloads reached an asymptotic maximum value when the depth of granular material in the columns was only three or four pipe-diameters, and never increased further as the columns were filled to the top (e.g. up to heights of 10 to 25 diameters). The floor-loads were stable and remained the same for days after filling. Aggressive tapping (e.g. hitting the containing pipe on the outside, manually with a wrench up and down the height and around the circumference) could increase (and occasionally decrease) the floor load substantially, but there was no sudden collapse or slumping to a state without significant wall friction effects. Considerable effort was required, repeatedly tapping over almost the entire column wall periphery, in order to produce floor-loads that corresponded to the total buoyancy-corrected weight of granular material added to the columns. Projecting the observed laboratory behavior to field conditions would imply that a stable floor-load condition, with only a slightly higher total floor pressure than the preexisting hydrostatic-head, would exist after a water-filled bore-hole is filled with sand or gravel. Significant seismic vibration (either a large nearby event or many micro-seismic events over an extended period) would likely be necessary before the full (buoyancy-corrected) weight of the sand and/or gravel would be ‘delivered’ to the bottom of the submerged column.« less

  3. Analysis of laterally loaded long or intermediate drilled shafts of small or large diameter in layered soil.

    DOT National Transportation Integrated Search

    2008-12-01

    This study has extended the capability of the SW model in order to predict the response of laterally loaded large diameter shafts considering 1) the influence of shaft type on the lateral shaft response; 2) the nonlinear behavior of shaft material an...

  4. Influence of the clearance on in-vitro tribology of large diameter metal-on-metal articulations pertaining to resurfacing hip implants.

    PubMed

    Rieker, Claude B; Schön, Rolf; Konrad, Reto; Liebentritt, Gernot; Gnepf, Patric; Shen, Ming; Roberts, Paul; Grigoris, Peter

    2005-04-01

    Large-diameter metal-on-metal articulations may provide an opportunity for wear reduction in total hip implants because earlier studies have shown that the formation of a fluid film that completely separates the bearing surfaces is theoretically possible. In such a lubrication mode and under ideal conditions, there is theoretically no amount of wear. Studies have suggested that the two primary parameters controlling the lubrication mode are the diameter and the clearance of the articulation. The goal of the present study was to experimentally investigate the influence of these two parameters on the wear behavior of large-diameter metal-on-metal articulations pertaining to resurfacing hip implants. The results of this in vitro investigation showed that longer running-in periods and higher amounts of running-in wear were associated with larger clearances.

  5. The Video Head Impulse Test (vHIT) of Semicircular Canal Function - Age-Dependent Normative Values of VOR Gain in Healthy Subjects.

    PubMed

    McGarvie, Leigh A; MacDougall, Hamish G; Halmagyi, G Michael; Burgess, Ann M; Weber, Konrad P; Curthoys, Ian S

    2015-01-01

    The video Head Impulse Test (vHIT) is now widely used to test the function of each of the six semicircular canals individually by measuring the eye rotation response to an abrupt head rotation in the plane of the canal. The main measure of canal adequacy is the ratio of the eye movement response to the head movement stimulus, i.e., the gain of the vestibulo-ocular reflex (VOR). However, there is a need for normative data about how VOR gain is affected by age and also by head velocity, to allow the response of any particular patient to be compared to the responses of healthy subjects in their age range. In this study, we determined for all six semicircular canals, normative values of VOR gain, for each canal across a range of head velocities, for healthy subjects in each decade of life. The VOR gain was measured for all canals across a range of head velocities for at least 10 healthy subjects in decade age bands: 10-19, 20-29, 30-39, 40-49, 50-59, 60-69, 70-79, 80-89. The compensatory eye movement response to a small, unpredictable, abrupt head rotation (head impulse) was measured by the ICS impulse prototype system. The same operator delivered every impulse to every subject. Vestibulo-ocular reflex gain decreased at high head velocities, but was largely unaffected by age into the 80- to 89-year age group. There were some small but systematic differences between the two directions of head rotation, which appear to be largely due to the fact that in this study only the right eye was measured. The results are considered in relation to recent evidence about the effect of age on VOR performance. These normative values allow the results of any particular patient to be compared to the values of healthy people in their age range and so allow, for example, detection of whether a patient has a bilateral vestibular loss. VOR gain, as measured directly by the eye movement response to head rotation, seems largely unaffected by aging.

  6. Early treatment with the von Rosen splint for neonatal instability of the hip is safe regarding avascular necrosis of the femoral head

    PubMed Central

    Wenger, Daniel; Samuelsson, Hanna; Düppe, Henrik; Tiderius, Carl Johan

    2016-01-01

    Background and purpose — Avascular necrosis of the femoral head (AVN) is a complication in treatment of developmental dysplasia of the hip (DDH). We evaluated the risk of AVN after early treatment in the von Rosen splint and measured the diameter of the ossific nucleus at 1 year of age. Children and methods — All children born in Malmö, Sweden, undergo clinical screening for neonatal instability of the hip (NIH). We reviewed 1-year radiographs of all children treated early for NIH in our department from 2003 through 2010. The diameter of the ossific nucleus was measured, and signs of AVN were classified according to Kalamchi-MacEwen. Subsequent radiographs, taken for any reason, were reviewed and a local registry of diagnoses was used to identify subsequent AVN. Results — 229 of 586 children referred because of suspected NIH received early treatment (age ≤ 1 week) for NIH during the study period. 2 of the 229 treated children (0.9%, 95% CI: 0.1–3.1) had grade-1 AVN. Both had spontaneous resolution and were asymptomatic during the observation time (6 and 8 years). 466 children met the inclusion criteria for measurement of the ossific nucleus. Neonatally dislocated hips had significantly smaller ossific nuclei than neonatally stable hips: mean 9.4 mm (95% CI: 9.1–9.8) vs. 11.1 mm (95% CI: 10.9–11.3) at 1 year (p < 0.001). Interpretation — Early treatment with the von Rosen splint for NIH is safe regarding AVN. The ossification of the femoral head is slower in children with NIH than in untreated children with neonatally stable hips. PMID:26730503

  7. The influence of head diameter and wall thickness on deformations of metallic acetabular press-fit cups and UHMWPE liners: a finite element analysis.

    PubMed

    Goebel, Paul; Kluess, Daniel; Wieding, Jan; Souffrant, Robert; Heyer, Horst; Sander, Manuela; Bader, Rainer

    2013-03-01

    To increase the range of motion of total hip endoprostheses, prosthetic heads need to be enlarged, which implies that the cup and/or liner thickness must decrease. This may have negative effects on the wear rate, because the acetabular cups and liners could deform during press-fit implantation and hip joint loading. We compared the metal cup and polyethylene liner deformations that occurred when different wall thicknesses were used in order to evaluate the resulting changes in the clearance of the articulating region. A parametric finite element model utilized three cup and liner wall thicknesses to analyze cup and liner deformations after press-fit implantation into the pelvic bone. The resultant hip joint force during heel strike was applied while the femur was fixed, accounting for physiological muscle forces. The deformation behavior of the liner under joint loading was therefore assessed as a function of the head diameter and the resulting clearance. Press-fit implantation showed diametral cup deformations of 0.096, 0.034, and 0.014 mm for cup wall thicknesses of 3, 5, and 7 mm, respectively. The largest deformations (average 0.084 ± 0.003 mm) of liners with thicknesses of 4, 6, and 8 mm occurred with the smallest cup wall thickness (3 mm). The smallest liner deformation (0.011 mm) was obtained with largest cup and liner wall thicknesses. Under joint loading, liner deformations in thin-walled acetabular cups (3 mm) reduced the initial clearance by about 50 %. Acetabular press-fit cups with wall thicknesses of ≤5 mm should only be used in combination with polyethylene liners >6 mm thick in order to minimize the reduction in clearance.

  8. Measurement of computed tomography dose profile with pitch variation using Gafchromic XR-QA2 and thermoluminescence dosimeter (TLD)

    NASA Astrophysics Data System (ADS)

    Purwaningsih, S.; Lubis, L. E.; Pawiro, S. A.; Soejoko, D. S.

    2016-03-01

    This research was aimed to check the patterns of dose profile on adult and pediatric head scan. We compared measurement result on dose profile along the z- axis rotation at peripheries and center phantom with a variety of pitch, i.e. 0.75, 1, 1.5 for adult and pediatric head protocol, keeping the rest of the scan parameters constant. Measurements were performed on homogeneous, cylindrical PMMA phantom with diameters of 16 and 10 cm using XR-QA2 Gafchromic film and TLD as dosimeters. The measurement result indicated a decrease in the dose about 50% and 47% for adult and pediatric head scan with the increase of pitch. For 0.75 value of pitch adult head scan, dose range for each position were (2.4 - 5.0) cGy, (3.1 - 5.3) cGy, (2.2 - 4.5) cGy, (2.8 - 5.3) cGy, and (3.3 - 5.6) cGy for position of center, 3, 6, 9 and 12 o'clock peripheral phantom position respectively. Dose profile for adult and pediatric head scan protocols has pattern curve with the maximum dose in the middle and tendency of symmetry near the edges, with different the plateau length along z- axis direction in accordance to the measurement position in the phantom.

  9. Patterns of Recurrence in Electively Irradiated Lymph Node Regions After Definitive Accelerated Intensity Modulated Radiation Therapy for Head and Neck Squamous Cell Carcinoma

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bosch, Sven van den, E-mail: sven.vandenbosch@radboudumc.nl; Dijkema, Tim; Verhoef, Lia C.G.

    Purpose: To provide a comprehensive risk assessment on the patterns of recurrence in electively irradiated lymph node regions after definitive radiation therapy for head and neck cancer. Methods and Materials: Two hundred sixty-four patients with stage cT2-4N0-2M0 squamous cell carcinoma of the oropharynx, larynx, or hypopharynx treated with accelerated intensity modulated radiation therapy between 2008 and 2012 were included. On the radiation therapy planning computed tomography (CT) scans from all patients, 1166 lymph nodes (short-axis diameter ≥5 mm) localized in the elective volume were identified and delineated. The exact sites of regional recurrences were reconstructed and projected on the initial radiationmore » therapy planning CT scan by performing coregistration with diagnostic imaging of the recurrence. Results: The actuarial rate of recurrence in electively irradiated lymph node regions at 2 years was 5.1% (95% confidence interval 2.4%-7.8%). Volumetric analysis showed an increased risk of recurrence with increasing nodal volume. Receiver operating characteristic analysis demonstrated that the summed long- and short-axis diameter is a good alternative for laborious volume calculations, using ≥17 mm as cut-off (hazard ratio 17.8; 95% confidence interval 5.7-55.1; P<.001). Conclusions: An important risk factor was identified that can help clinicians in the pretreatment risk assessment of borderline-sized lymph nodes. Not overtly pathologic nodes with a summed diameter ≥17 mm may require a higher than elective radiation therapy dose. For low-risk elective regions (all nodes <17 mm), the safety of dose de-escalation below the traditional 45 to 50 Gy should be investigated.« less

  10. Implementation of 0.7 in. diameter strands in prestressed concrete girders.

    DOT National Transportation Integrated Search

    2013-03-01

    For several years, 0.7 in. diameter strands have been successfully used in cable bridges and for mining applications. Using these large diameter strands at 2 in. by 2 in. spacing in pretensioned concrete girders results in approximately 35% increase ...

  11. MSFC Optical Metrology: A National Resource

    NASA Technical Reports Server (NTRS)

    Burdine, Robert

    1998-01-01

    A national need exists for Large Diameter Optical Metrology Services. These services include the manufacture, testing, and assurance of precision and control necessary to assure the success of large optical projects. "Best Practices" are often relied on for manufacture and quality controls while optical projects are increasingly more demanding and complex. Marshall Space Flight Center (MSFC) has acquired unique optical measurement, testing and metrology capabilities through active participation in a wide variety of NASA optical programs. An overview of existing optical facilities and metrology capabilities is given with emphasis on use by other optical projects. Cost avoidance and project success is stressed through use of existing MSFC facilities and capabilities for measurement and metrology controls. Current issues in large diameter optical metrology are briefly reviewed. The need for a consistent and long duration Large Diameter Optical Metrology Service Group is presented with emphasis on the establishment of a National Large Diameter Optical Standards Laboratory. Proposals are made to develop MSFC optical standards and metrology capabilities as the primary national standards resource, providing access to MSFC Optical Core Competencies for manufacturers and researchers. Plans are presented for the development of a national lending library of precision optical standards with emphasis on cost avoidance while improving measurement assurance.

  12. Characterizing Discourse Deficits Following Penetrating Head Injury: A Preliminary Model

    ERIC Educational Resources Information Center

    Coelho, Carl; Le, Karen; Mozeiko, Jennifer; Hamilton, Mark; Tyler, Elizabeth; Krueger, Frank; Grafman, Jordan

    2013-01-01

    Purpose: Discourse analyses have demonstrated utility for delineating subtle communication deficits following closed head injuries (CHIs). The present investigation examined the discourse performance of a large group of individuals with penetrating head injury (PHI). Performance was also compared across 6 subgroups of PHI based on lesion locale. A…

  13. High-Resolution, Large-Area, Nano Imprint Lithography

    DTIC Science & Technology

    2009-08-27

    oxides as the seed layers can provide implication as the general synthetic route for the spontaneous growth of metal - silicide nanowires in large...nano-island array preparation , we have successfully fabricated patterned magnetic recording media as described in Fig. 2. About ~30 nm diameter Si...that we fabricated at UCSD with 5-50 nm diameter magnetic islands was used, since a large- area, hard disk size preparation was necessary, and since a

  14. Improved patient size estimates for accurate dose calculations in abdomen computed tomography

    NASA Astrophysics Data System (ADS)

    Lee, Chang-Lae

    2017-07-01

    The radiation dose of CT (computed tomography) is generally represented by the CTDI (CT dose index). CTDI, however, does not accurately predict the actual patient doses for different human body sizes because it relies on a cylinder-shaped head (diameter : 16 cm) and body (diameter : 32 cm) phantom. The purpose of this study was to eliminate the drawbacks of the conventional CTDI and to provide more accurate radiation dose information. Projection radiographs were obtained from water cylinder phantoms of various sizes, and the sizes of the water cylinder phantoms were calculated and verified using attenuation profiles. The effective diameter was also calculated using the attenuation of the abdominal projection radiographs of 10 patients. When the results of the attenuation-based method and the geometry-based method shown were compared with the results of the reconstructed-axial-CT-image-based method, the effective diameter of the attenuation-based method was found to be similar to the effective diameter of the reconstructed-axial-CT-image-based method, with a difference of less than 3.8%, but the geometry-based method showed a difference of less than 11.4%. This paper proposes a new method of accurately computing the radiation dose of CT based on the patient sizes. This method computes and provides the exact patient dose before the CT scan, and can therefore be effectively used for imaging and dose control.

  15. Transverse tensile and stress rupture properties of gamma/gamma prime-delta directionally solidified eutectic

    NASA Technical Reports Server (NTRS)

    Gray, H. H.

    1976-01-01

    Tensile and stress rupture properties were determined primarily at 760 C for specimens oriented at various angles (0 deg, 10 deg, 45 deg, and 90 deg) from the solidification direction of bars and/or slabs of the Ni-20Cb-6Cr-2.5A (gamma/gamma prime-delta) eutectic. Threaded-head specimens yielded longer rupture lives with significantly less scatter than did tapered-head specimens. Miniature specimens are suitable for determining traverse tensile and rupture properties of 1.2 centimeter diameter bar stock. The 300 hour rupture stress at 760 C for specimens oriented at 10 deg from the solidification direction was reduced from 740 to 460 MPa, and to 230 MPa for material oriented at either 45 deg or 90 deg.

  16. A nerve stimulation method to selectively recruit smaller motor-units in rat skeletal muscle.

    PubMed

    van Bolhuis, A I; Holsheimer, J; Savelberg, H H

    2001-05-30

    Electrical stimulation of peripheral nerve results in a motor-unit recruitment order opposite to that attained by natural neural control, i.e. from large, fast-fatiguing to progressively smaller, fatigue-resistant motor-units. Yet animal studies involving physiological exercise protocols of low intensity and long duration require minimal fatigue. The present study sought to apply a nerve stimulation method to selectively recruit smaller motor-units in rat skeletal muscle. Two pulse generators were used, independently supplying short supramaximal cathodal stimulating pulses (0.5 ms) and long subthreshold cathodal inactivating pulses (1.5 s) to the sciatic nerve. Propagation of action potentials was selectively blocked in nerve fibres of different diameter by adjusting the strength of the inactivating current. A tensile-testing machine was used to gauge isometric muscle force of the plantaris and both heads of the gastrocnemius muscle. The order of motor-unit recruitment was estimated from twitch characteristics, i.e. peak force and relaxation time. The results showed prolonged relaxation at lower twitch peak forces as the intensity of the inactivating current increased, indicating a reduction of the number of large motor-units to force production. It is shown that the nerve stimulation method described is effective in mimicking physiological muscle control.

  17. 75 FR 11119 - Certain Large Diameter Carbon and Alloy Seamless Standard, Line, and Pressure Pipe From Japan...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... Carbon and Alloy Seamless Standard, Line, and Pressure Pipe From Japan: Extension of Time Limit for... review of the antidumping duty order on certain large diameter carbon and alloy seamless standard, line... manufacturers/exporters: JFE Steel Corporation; Nippon Steel Corporation; NKK Tubes; and Sumitomo Metal...

  18. PERFORMANCE EVALUATION OF AN INNOVATIVE FIBER REINFORCED GEOPOLYMER SPRAY-APPLIED MORTAR FOR LARGE DIAMETER WASTEWATER MAIN REHABILITATION IN HOUSTON, TX

    EPA Science Inventory

    This report describes the performance evaluation of a fiber reinforced geopolymer spray-applied mortar, which has potential as a structural alternative to traditional open cut techniques used in large-diameter sewer pipes. Geopolymer is a sustainable green material that incorpor...

  19. 7 CFR 51.2952 - Size specifications.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... a round opening 96/64 inches in diameter; (b) Jumbo size. Jumbo size means walnuts of which not over 12 percent, by count, pass through a round opening 80/64 inches in diameter; (c) Large size. Large size means walnuts of which not over 12 percent, by count, pass through a round opening 77/64 inches in...

  20. 42 CFR 84.130 - Supplied-air respirators; description.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... of air when the blower is not operating, a strong large-diameter hose having a low resistance to... wearer's vision and permit easy access to the external surface of such window(s) for cleaning. (c) Type... immediately dangerous to life or health, which consists of a strong large-diameter hose with low resistance to...

  1. 42 CFR 84.130 - Supplied-air respirators; description.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... of air when the blower is not operating, a strong large-diameter hose having a low resistance to... wearer's vision and permit easy access to the external surface of such window(s) for cleaning. (c) Type... immediately dangerous to life or health, which consists of a strong large-diameter hose with low resistance to...

  2. Large Diameter, Radiative Extinction Experiments with Decane Droplets in Microgravity

    NASA Technical Reports Server (NTRS)

    Easton, John; Tien, James; Dietrich, Daniel

    1999-01-01

    The extinction of a diffusion flame is of fundamental interest in combustion science. Linan, Law, and Chung and Law analytically and experimentally determined an extinction boundary in terms of droplet diameter and pressure for a single droplet due to Damkohler, or blowoff, extinction. More recently, other researchers demonstrated extinction due to finite rate kinetics in reduced gravity for free droplets of heptane. Chao modeled the effect of radiative heat loss on a quasi-steady spherically symmetric single droplet burning in the absence of buoyancy. They determined that for increasing droplet diameter, a second limit can be reached such that combustion is no longer possible. This second, larger droplet diameter limit arises due to radiative heat loss, which increases with increasing droplet and flame diameter. This increase in radiative heat loss arises due to an increase in the surface area of the flame. Recently, Marchese modeled fuel droplets with detailed chemistry and radiative effects, and compared the results to other work. The modeling also showed the importance of radiative loss and radiative extinction Experiments examined the behavior of a large droplet of decane burning in reduced gravity onboard the NASA Lewis DC-9 aircraft, but did not show a radiative extinction boundary due to g-jitter (Variations in gravitational level and direction) effects. Dietrich conducted experiments in the reduced gravity environment of the Space Shuttle. This work showed that the extinction diameter of methanol droplets increased when the initial diameter of the droplets was large (in this case, approximately 5 mm). Theoretical results agreed with these experimental results only when the theory included radiative effects . Radiative extinction was experimentally verified by Nayagam in a later Shuttle mission. The following work focuses on the combustion and extinction of a single fuel droplet. The goal is to experimentally determine a large droplet diameter limit that arises due to radiative heat loss from the flame to the surroundings.

  3. Modeling and Control of a Tethered Rotorcraft

    DTIC Science & Technology

    2010-07-30

    viscous damper with damping coefficient Cv. Visco-elastic line force is written in terms of components Δx, Δy, and Δz, of the difference vector formed...tether drag coefficient CS = tether damping coefficient Cv = viscous damping coefficient d = diameter of the tether En = n x n identity matrix FA...matrix consisting of Iyy and Izz k = rotor head stiffness KLAT, KLON = steady state flapping gains Ks, Kv = static and viscous stiffness Lj

  4. The possibility to increase the rated output as a result of index tests performed in Iron Gates II- Romania

    NASA Astrophysics Data System (ADS)

    Novac, D.; Pantelimon, D.; Popescu, E.

    2010-08-01

    The Index Tests have been used for many years to obtain the optimized cam corellation between wicket gates and runner blades for double regulated turbines (Kaplan, bulb). The cam is based on homologous model tests and is verified by site measurements, as model tests generally do not reproduce the exact intake configuration. Index Tests have also a considerable importance for checking of the relative efficiency curve of all type of turbines and can demonstrate if the prototype efficiency curve at plant condition has the shape expected from the test of the homologues model. During the Index Tests measurements the influence of all losses at multiple points of turbine operation can be proved. This publication deals with an overview on the Index Tests made after modernization of large bulb units in Iron Gates II - Romania. These field tests, together with the comparative, fully homologous tests for the new hydraulic shape of the runner blades have confirmed the smooth operational behavior and the guaranteed performance. Over the whole "guaranteed operating range" for H = 8m, the characteristic of the Kaplan curve (enveloping curve to the proppeler curves), agreed very well to the predicted efficiency curve from the hydraulic prototype hill chart. The new cam correlation have been determined for different head and realised in the governor, normally based on model tests. The guaranteed, maximum turbine output for H = 7,8m is specified with 32, 5 MW. The maximum measured turbine output during the Index Tests on cam operation was 35,704 MW at the net head of 7,836 m. This coresponds to 35,458 MW for the specified head H= 7, 8 m. All these important improvements ensure a significant increase of annual energy production without any change of the civil construction and without increasing the runner diameter. Also the possibility to increase the turbine rated output is evident.

  5. Vascular labeling of the head and neck vessels: Technique, advantages and limitations.

    PubMed

    Gálvez, Alba; Caraballo, José-Leonardo; Manzanares-Céspedes, María-Cristina; Valdivia-Gandur, Iván; Figueiredo, Rui; Valmaseda-Castellón, Eduard

    2017-05-01

    Vascular staining techniques have been used to describe the vascular structures of several anatomic areas. However, few reports have described this procedure in the head and neck region. This paper describes a head and neck vascular labeling procedure, and describes some of the technical complications that may occur. Fifteen specimen cadaver heads were prepared. After drying the vascular system, the internal carotid arteries were ligated and a solution with latex and a gelling agent was injected into the internal carotid arteries and external jugular veins. Two different colors were employed to differentiate arteries from veins. A total of 60ml latex was injected into each blood vessel. Subsequently, the specimens were refrigerated at 5°C for a minimum of 24 hours. Finally, a dissection was performed to identify the venous and arterial systems of the maxillofacial region. In most specimens, correct identification of the vascular structures (lingual artery, pterigoyd plexus, and the major palatal arteries, among others) was possible. However, in three heads a major technical problem occurred (the latex remained liquid), making the dissection unfeasible. Other minor complications such as latex obstruction due to the presence of atheromas were found in two further specimens. The vascular labeling technique is a predictable, effective and simple method for analyzing the vascular system of the maxillofacial area in cadaveric studies, including vessels of reduced diameter or with an intraosseous course. This procedure can be especially useful to teach vascular anatomy to dental students and postgraduate residents. Key words: Blood vessels, vascular casting, vascular labeling, head and neck arteries, carotid arteries, jugular veins.

  6. A Study of Leadership Effectiveness in a Large VET Institution in Australia

    ERIC Educational Resources Information Center

    Adams, Don; Gamage, David T.

    2008-01-01

    Purpose: This paper aims to focus on a study of the effectiveness of head teacher leadership within TAFE NSW. Design/methodology/approach: Quantitative and qualitative methods were employed to identify and measure the effective leadership attributes of the head teachers. The research sample consisted of head teachers and teachers. Findings: The…

  7. Head Start, 4 years After Completing the Program

    ERIC Educational Resources Information Center

    Kim, Young-Joo

    2013-01-01

    This paper studies the effect of the Head Start program on children's achievements in reading and math tests during their first 4 years of schooling after completing the program. Using nationally representative data from the Early Childhood Longitudinal Study, I found large measurement error in the parental reports of Head Start attendance, which…

  8. Derivation of an Extra-Large PASGT Helmet

    DTIC Science & Technology

    1988-07-01

    IED GROUP SU"!jRUP j" Anthropometry ~p Head Length ) I II jHead Circumfirence, Helmet Standoff, Head Breadth PASGT Helmets t IIABSTRACT (Conhwe on m.wn...publication. I,9 LIST OF REFZRENCES 1. DF, STRNC-ICAA, dtd 26 January 1987, XL PASGT Helmet. 2. Military Specification, MIL-H-44099A (Revision 1986). Helmet

  9. Steric interactions lead to collective tilting motion in the ribosome during mRNA-tRNA translocation

    NASA Astrophysics Data System (ADS)

    Nguyen, Kien; Whitford, Paul C.

    2016-02-01

    Translocation of mRNA and tRNA through the ribosome is associated with large-scale rearrangements of the head domain in the 30S ribosomal subunit. To elucidate the relationship between 30S head dynamics and mRNA-tRNA displacement, we apply molecular dynamics simulations using an all-atom structure-based model. Here we provide a statistical analysis of 250 spontaneous transitions between the A/P-P/E and P/P-E/E ensembles. Consistent with structural studies, the ribosome samples a chimeric ap/P-pe/E intermediate, where the 30S head is rotated ~18°. It then transiently populates a previously unreported intermediate ensemble, which is characterized by a ~10° tilt of the head. To identify the origins of head tilting, we analyse 781 additional simulations in which specific steric features are perturbed. These calculations show that head tilting may be attributed to specific steric interactions between tRNA and the 30S subunit (PE loop and protein S13). Taken together, this study demonstrates how molecular structure can give rise to large-scale collective rearrangements.

  10. Improvement of chemical vapor deposition process for production of large diameter carbon base monofilaments

    NASA Technical Reports Server (NTRS)

    Hough, R. L.; Richmond, R. D.

    1971-01-01

    Research was conducted to develop large diameter carbon monofilament, containing 25 to 35 mole % element boron, in the 2.0 to 10.0 mil diameter range using the chemical vapor deposition process. The objective of the program was to gain an understanding of the critical process variables and their effect on fiber properties. Synthesis equipment was modified to allow these variables to be studied. Improved control of synthesis variables permitted reduction in scatter of properties of the monofilaments. Monofilaments have been synthesized in the 3.0 to nearly 6.0 mil diameter range having measured values up to 552,000 psi for ultimate tensile strength and up to 30 million psi for elastic modulus.

  11. [Clinicopathologic features of primary mucosal CD30-positive T-cell lymphoproliferative disorders in head and neck region].

    PubMed

    Liu, F; Li, M; Zhang, L Y; Guo, L; Hu, W W; Rao, H L

    2018-06-08

    Objective: To study clinicopathologic features, prognosis and differential diagnoses of primary mucosal CD30-positive T-cell lymphoproliferative disorders of the head and neck(mCD30(+) TLPD-head and neck). Methods: Three cases of mCD30(+) TLPD-head and neck were collected from January 2014 to April 2017 at Sun Yat-Sen University Foshan Hospital. A literature review of mCD30(+) TLPD of head and neck was provided. Results: All three cases presented with either bulging/exophytic nodule or mucosal ulcer/erosion. Morphologically, the tumor consisted of diffuse proliferation of uniform, large atypical mononuclear lymphoid cells that showed irregular or polymorphic nuclei with small nucleoli, and abundant pale or amphophilic cytoplasm. Hallmark cells with eccentric, horseshoe, kidney-like, or doughnut-shaped nuclei were present. While mitotic figures were present, no tumor necrosis was found. Eosinophilc infiltration was obvious in the background. The atypical large lymphoid cells had a immunophenotype of CD30(+) /CD3(+) /CD4(+) /CD56(-) along with positive cytotoxic molecule. While being negative for EBER/ALK/CD20/CD8, TCR rearrangement was found in 2 out of 3 cases. Three patients were cured after excision without relapse and metastasis.The two patients with TCR rearrangement didn't show aggressive clinical course. Conclusions: mCD30(+) TLPD-head and neck is a rare benign lymphoproliferative disorder with spontaneous regression. It should be differentiated from cutaneous CD30(+) anaplstic large cell lymphoma, lymphomatoid papulosis, and EBV-related mucocutaneous ulcer. Correct recognition of mCD30(+) TLPD of head and neck is important to avoid overtreatment.

  12. Mechanical and deformation analyses of pile foundation for supporting structure of off-shore wind turbine at Changhua coast in Taiwan

    NASA Astrophysics Data System (ADS)

    Wang, W. C.; Lin, D. G.

    2015-12-01

    This study investigates the bearing capacities and mechanical behaviors of pile foundation installed on the seabed of wind farm near Chang-Hua coast of western Taiwan for the supporting structure of offshore wind turbine. A series of three-dimensional (3-D) numerical modeling of pile foundation subjected to various types of combined loading were carried out using Plaix-3D finite element program to investigate the interactive behaviors between soil and pile. In the numerical modeling, pile diameter, pile length and pile spacing were selected as design parameters to inspect their effects on the bearing capacities and deformation behaviors of the pile foundation. For a specific design parameter combination, one can obtain the corresponding loading-displacement curve, various ultimate bearing capacities, V-H (Vertical-Horizontal combined loading) ultimate bearing capacity envelope, and p-ycurve of pile foundation. Numerical results indicate that: (1) Large displacement and plastic points at ultimate state mostly distribute and concentrate in the topsoil of seabed and around pile head. (2) The soil resistance on the soil-pile interface is ascending with the increases of depth, pile diameter and pile length. (3) The vertical and horizontal bearing capacities of pile group increase significantly with the increase of pile diameter. (4) The vertical and bending moment capacities of pile group increase greatly with the increase of pile length whereas the horizontal capacity is almost insensitive to pile length. (5) The bending moment of pile is highly influenced by the pile spacing. (6) For different design parameters, the shape of ultimate bearing capacity envelopes of pile group on V-H plane is similar while the envelopes will expand as the design parameters increase. For different loading levels of bending moment, the envelopes on V-H plane will contract gradually as the bending moment loading increasing.

  13. A prospective study of fetal head growth, autistic traits and autism spectrum disorder

    PubMed Central

    Blanken, Laura M. E.; Dass, Alena; Alvares, Gail; van der Ende, Jan; Schoemaker, Nikita K.; El Marroun, Hanan; Hickey, Martha; Pennell, Craig; White, Scott; Maybery, Murray T.; Dissanayake, Cheryl; Jaddoe, Vincent W. V.; Verhulst, Frank C.; Tiemeier, Henning; McIntosh, Will; Whitehouse, Andrew

    2018-01-01

    Altered trajectories of brain growth are often reported in Autism Spectrum Disorder (ASD), particularly during the first year of life. However, less is known about prenatal head growth trajectories, and no study has examined the relation with postnatal autistic symptom severity. The current study prospectively examined the association between fetal head growth and the spectrum of autistic symptom severity in two large population‐based cohorts, including a sample of individuals with clinically diagnosed ASD. This study included 3,820 children from two longitudinal prenatal cohorts in The Netherlands and Australia, comprising 60 individuals with a confirmed diagnosis of ASD. Latent growth curve models were used to examine the relationship between fetal head circumference measured at three different time points and autistic traits measured in postnatal life using either the Social Responsiveness Scale or the Autism‐Spectrum Quotient. While lower initial prenatal HC was weakly associated with increasing autistic traits in the Dutch cohort, this relationship was not observed in the Australian cohort, nor when the two cohorts were analysed together. No differences in prenatal head growth were found between individuals with ASD and controls. This large population‐based study identified no consistent association across two cohorts between prenatal head growth and postnatal autistic traits. Our mixed findings suggest that further research in this area is needed. Autism Res 2018, 11: 602–612. © 2018 The Authors Autism Research published by International Society for Autism Research and Wiley Periodicals, Inc. Lay Summary It is not known whether different patterns of postnatal brain growth in Autism Spectrum Disorder (ASD) also occurs prenatally. We examined fetal head growth and autistic symptoms in two large groups from The Netherlands and Australia. Lower initial prenatal head circumference was associated with autistic traits in the Dutch, but not the Australian, group. No differences in head growth were found in individuals with ASD and controls when the data was combined. Our mixed findings suggest that more research in this area is needed. PMID:29356450

  14. MO-E-17A-08: Attenuation-Based Size Adjusted, Scanner-Independent Organ Dose Estimates for Head CT Exams: TG 204 for Head CT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McMillan, K; Bostani, M; Cagnon, C

    Purpose: AAPM Task Group 204 described size specific dose estimates (SSDE) for body scans. The purpose of this work is to use a similar approach to develop patient-specific, scanner-independent organ dose estimates for head CT exams using an attenuation-based size metric. Methods: For eight patient models from the GSF family of voxelized phantoms, dose to brain and lens of the eye was estimated using Monte Carlo simulations of contiguous axial scans for 64-slice MDCT scanners from four major manufacturers. Organ doses were normalized by scannerspecific 16 cm CTDIvol values and averaged across all scanners to obtain scanner-independent CTDIvol-to-organ-dose conversion coefficientsmore » for each patient model. Head size was measured at the first slice superior to the eyes; patient perimeter and effective diameter (ED) were measured directly from the GSF data. Because the GSF models use organ identification codes instead of Hounsfield units, water equivalent diameter (WED) was estimated indirectly. Using the image data from 42 patients ranging from 2 weeks old to adult, the perimeter, ED and WED size metrics were obtained and correlations between each metric were established. Applying these correlations to the GSF perimeter and ED measurements, WED was calculated for each model. The relationship between the various patient size metrics and CTDIvol-to-organ-dose conversion coefficients was then described. Results: The analysis of patient images demonstrated the correlation between WED and ED across a wide range of patient sizes. When applied to the GSF patient models, an exponential relationship between CTDIvol-to-organ-dose conversion coefficients and the WED size metric was observed with correlation coefficients of 0.93 and 0.77 for the brain and lens of the eye, respectively. Conclusion: Strong correlation exists between CTDIvol normalized brain dose and WED. For the lens of the eye, a lower correlation is observed, primarily due to surface dose variations. Funding Support: Siemens-UCLA Radiology Master Research Agreement; Disclosures - Michael McNitt-Gray: Institutional Research Agreement, Siemens AG; Research Support, Siemens AG; Consultant, Flaherty Sensabaugh Bonasso PLLC; Consultant, Fulbright and Jaworski.« less

  15. 78 FR 41366 - Certain Large Diameter Carbon and Alloy Seamless Standard, Line, and Pressure Pipe (Over 4 1/2

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-10

    ... Carbon and Alloy Seamless Standard, Line, and Pressure Pipe (Over 4 \\1/2\\ Inches) From Japan: Preliminary... seamless standard, line, and pressure pipe (over 4 \\1/2\\ inches) (large diameter seamless pipe) from Japan.../exporters of subject merchandise, Canadian Natural Resources Limited (CNRL), JFE Steel Corporation (JFE...

  16. 75 FR 18153 - Certain Large Diameter Carbon and Alloy Seamless Standard, Line, and Pressure Pipe From Japan...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-09

    ... Carbon and Alloy Seamless Standard, Line, and Pressure Pipe From Japan: Extension of Time Limit for... review of the antidumping duty order on certain large diameter carbon and alloy seamless standard, line... Carbon and Alloy Seamless Standard, Line and Pressure Pipe from Japan: Extension of Time Limit for...

  17. Snag distributions in relation to human access in ponderosa pine forests

    Treesearch

    Jeff P. Hollenbeck; Lisa J. Bate; Victoria A. Saab; John F. Lehmkuhl

    2013-01-01

    Ponderosa pine (Pinus ponderosa) forests in western North America provide habitat for numerous cavity-using wildlife species that often select large-diameter snags for nesting and roosting. Yet large snags are often removed for their commercial and firewood values. Consequently we evaluated effects of human access on snag densities and diameter-class distributions at...

  18. Design method of large-diameter rock-socketed pile with steel casing

    NASA Astrophysics Data System (ADS)

    Liu, Ming-wei; Fang, Fang; Liang, Yue

    2018-02-01

    There is a lack of the design and calculation method of large-diameter rock-socketed pile with steel casing. Combined with the “twelfth five-year plan” of the National Science & Technology Pillar Program of China about “Key technologies on the ports and wharfs constructions of the mountain canalization channels”, this paper put forward the structured design requirements of concrete, steel bar distribution and steel casing, and a checking calculation method of the bearing capacity of the normal section of the pile and the maximum crack width at the bottom of the steel casing. The design method will have some degree of guiding significance for the design of large-diameter rock-socketed pile with steel casing.

  19. Measurement of the spatial dependence of temperature and gas and soot concentrations within large open hydrocarbon fuel fires

    NASA Technical Reports Server (NTRS)

    Johnson, H. T.; Linley, L. J.; Mansfield, J. A.

    1982-01-01

    A series of large-scale JP-4 fuel pool fire tests was conducted to refine existing mathematical models of large fires. Seven tests were conducted to make chemical concentration and temperature measurements in 7.5 and 15 meter-diameter pool fires. Measurements were made at heights of 0.7, 1.4, 2.9, 5.7, 11.4, and 21.3 meters above the fires. Temperatures were measured at up to 50 locations each second during the fires. Chemistry samples were taken at up to 23 locations within the fires and analyzed for combustion chemistry and soot concentration. Temperature and combustion chemistry profiles obtained during two 7.5 meter-diameter and two 15 meter-diameter fires are included.

  20. Influence of incubation temperature on hatching success, energy expenditure for embryonic development, and size and morphology of hatchlings in the oriental garden lizard, Calotes versicolor (Agamidae).

    PubMed

    Ji, Xiang; Qiu, Qing-Bo; Diong, Cheong-Hoong

    2002-06-01

    We incubated eggs of Calotes versicolor at four constant temperatures ranging from 24 degrees C to 33 degrees C to assess the effects of incubation temperature on hatching success, embryonic use of energy, and hatchling phenotypes that are likely to affect fitness. All viable eggs increased in mass throughout incubation due to absorption of water, and mass gain during incubation was dependent on initial egg mass and incubation temperature. The average duration of incubation at 24 degrees C, 27 degrees C, 30 degrees C, and 33 degrees C was 82.1 days, 60.5 days, 51.4 days, and 50.3 days, respectively. Incubation temperature affected hatching success, energy expenditure for embryonic development, and several hatchling traits examined, but it did not affect the sex ratio of hatchlings. Hatching success was lowest (3.4%) at 33 degrees C, but a higher incidence of deformed embryos was recorded from eggs incubated at this temperature compared to eggs incubated at lower temperatures. Most of the deformed embryos died at the last stage of incubation. Energy expenditure for embryonic development was, however, higher in eggs incubated at 33 degrees C than those similarly incubated at lower temperatures. A prolonged exposure of eggs of C. versicolor at 33 degrees C appears to have an adverse and presumably lethal effect on embryonic development. Hatching success at 24 degrees C was also low (43.3%), but hatchlings incubated at 24 degrees C did not differ in any of the examined traits from those incubated at two intermediate temperatures (27 degrees C and 30 degrees C). Hatchlings incubated at 33 degrees C were smaller (snout-vent length, SVL) than those incubated at lower incubation temperatures and had larger mass residuals (from the regression on SVL) as well as shorter head length, hindlimb length, tympanum diameter, and eye diameter relative to SVL. Hatchlings from 33 degrees C had significantly lower scores on the first axis of a principal component analysis representing mainly SVL-free head size (length and width) and fore- and hindlimb lengths, but they had significantly higher scores on the second axis mainly representing SVL-free wet body mass. Variation in the level of fluctuating asymmetry in eye diameter associated with incubation temperatures was quite high, and it was clearly consistent with the prediction that environmental stress associated with the highest incubation temperatures might produce the highest level of asymmetry. Newly emerged hatchlings exhibited sexual dimorphism in head width, with male hatchlings having larger head width than females. Copyright 2002 Wiley-Liss, Inc.

  1. Effects of Multiple Drilling on the Ischemic Capital Femoral Epiphysis of Immature Piglets

    PubMed Central

    Gong, Sun Young; Kim, Hyun Woo; Park, Hui-Wan; Lee, Seung Yup

    2011-01-01

    Purpose This study investigated the effects of multiple drilling on the immature capital femoral epiphysis following ischemic injury in a piglet model. Materials and Methods Ischemic necrosis of capital femoral epiphysis was induced bilaterally in 12 piglets using a cervical ligation method. Three weeks later, medial, central, and lateral 3 drill holes were made on the left femoral head using 0.062" K-wire. At 3, 6, 9, and 12 weeks following the multiple drilling, femoral heads were harvested from each three piglets. On histologic examination, percent of revascularization, percent of osteoblast surface, capital femoral epiphyseal quotient and proximal femoral growth plate height were evaluated. Untreated right femoral heads served as control. Results While percent of revascularization of left capital femoral epiphysis with multiple drilling was significantly higher than untreated control side (p<0.001), percent of osteoblast surface, capital femoral epiphyseal quotient and proximal femoral growth plate height showed no significant difference. Conclusion This study indicates that multiple drilling could promote revascularization of ischemic capital femoral epiphysis, and multiple drilling does not appear to produce bony physeal bars at short-term, if using small diameter drill. However, multiple drilling alone does not seem to prevent femoral head deformity or to promote new bone formation. PMID:21786447

  2. Wear of ultra-high molecular weight polyethylene against damaged and undamaged stainless steel and diamond-like carbon-coated counterfaces.

    PubMed

    Firkins, P; Hailey, J L; Fisher, J; Lettington, A H; Butter, R

    1998-10-01

    The wear of ultra-high molecular weight polyethylene (UHMWPE) in artificial joints and the resulting wear debris-induced osteolysis remains a major clinical concern in the orthopaedic sector. Third-body damage of metallic femoral heads is often cited as a cause of accelerated polyethylene wear, and the use of ceramic femoral heads in the hip is gaining increasing favour. In the knee prostheses and for smaller diameter femoral heads, the application of hard surface coatings, such as diamond-like carbon, is receiving considerable attention. However, to date, there has been little or no investigation of the tribology of these coatings in simulated biological environments. In this study, diamond-like carbon (DLC) has been compared to stainless steel in its undamaged form and following simulated third-body damage. The wear of UHMWPE was found to be similar when sliding against undamaged DLC and stainless steel counterfaces. DLC was found to be much more damage resistant than DLC. Under test conditions that simulate third-body damage to the femoral head, the wear of UHMWPE was seven times lower against DLC than against stainless steel (P < 0.05). The study shows DLC has considerable potential as a femoral bearing surface in artificial joints.

  3. Midterm results of Magnum large head metal-on-metal total hip arthroplasty.

    PubMed

    Aguado-Maestro, I; Cebrián Rodríguez, E; Paredes Herrero, E; Brunie Vegas, F; Oñate Miranda, M; Fernández García, N; García Alonso, M

    2018-06-11

    We present the results of the prospective follow up of a sample of large head metal-metal total hip arthroplasty obtained after the safety alert regarding a higher incidence of revision of these implants. All patients implanted with the Recap-M2a-Magnum cup between 2008 and 2011 were included. They were prospectively reviewed recording Harris Hip Score, clinical symptoms of chromium or cobalt intoxication. Serum levels of these ions were requested as well as X-Rays and ultrasonography. An MRI was performed in the cases of positive ultrasonography. Twenty-six males with a mean age of 48.54 years [32-62, SD: 7.18] were included. An anterolateral approach and Bi-Metric (7) and F-40 (19) stems were used. Cephalic diameters ranged 42-52 (mode: 46) and the mean cup inclination was 39.35° [21-59°, SD: 9.78]. During follow-up (7.3 years [5.9-9.4; SD: .78]), 3 patients (11.5%) underwent revision (2 cases aseptic loosening, 1 pseudotumour). Mean time until revision was 5.4 years [3.1-8.0; SD: 2.48]. The accumulated survival probability was 88.5% (95% CI 76.3-100%). Harris Hip Score was 94.47 [66.5-100; SD: 8.94] and the patients showed no metallic intoxication symptoms. The levels of chromium were 1.88 mcg/dl [0.6-3.9] and cobalt 1,74 mcg/dl [0.5-5,6]. One pseudotumour was found in an asymptomatic patient, and small amounts of periarticular liquid were found in 5 patients (19.2%) DISCUSSION AND CONCLUSIONS: High revision rates are still found when follow up is extended due to aseptic loosening and pseudotumour formation. MRI might not be the most adequate test to study the complications of these prostheses. Copyright © 2018 SECOT. Publicado por Elsevier España, S.L.U. All rights reserved.

  4. Contribution of the frontal eye field to gaze shifts in the head-unrestrained rhesus monkey: neuronal activity.

    PubMed

    Knight, T A

    2012-12-06

    The frontal eye field (FEF) has a strong influence on saccadic eye movements with the head restrained. With the head unrestrained, eye saccades combine with head movements to produce large gaze shifts, and microstimulation of the FEF evokes both eye and head movements. To test whether the dorsomedial FEF provides commands for the entire gaze shift or its separate eye and head components, we recorded extracellular single-unit activity in monkeys trained to make large head-unrestrained gaze shifts. We recorded 80 units active during gaze shifts, and closely examined 26 of these that discharged a burst of action potentials that preceded horizontal gaze movements. These units were movement or visuomovement related and most exhibited open movement fields with respect to amplitude. To reveal the relations of burst parameters to gaze, eye, and/or head movement metrics, we used behavioral dissociations of gaze, eye, and head movements and linear regression analyses. The burst number of spikes (NOS) was strongly correlated with movement amplitude and burst temporal parameters were strongly correlated with movement temporal metrics for eight gaze-related burst neurons and five saccade-related burst neurons. For the remaining 13 neurons, the NOS was strongly correlated with the head movement amplitude, but burst temporal parameters were most strongly correlated with eye movement temporal metrics (head-eye-related burst neurons, HEBNs). These results suggest that FEF units do not encode a command for the unified gaze shift only; instead, different units may carry signals related to the overall gaze shift or its eye and/or head components. Moreover, the HEBNs exhibit bursts whose magnitude and timing may encode a head displacement signal and a signal that influences the timing of the eye saccade, thereby serving as a mechanism for coordinating the eye and head movements of a gaze shift. Copyright © 2012 IBRO. Published by Elsevier Ltd. All rights reserved.

  5. Large-Area Fabrication of Droplet Pancake Bouncing Surface and Control of Bouncing State.

    PubMed

    Song, Jinlong; Gao, Mingqian; Zhao, Changlin; Lu, Yao; Huang, Liu; Liu, Xin; Carmalt, Claire J; Deng, Xu; Parkin, Ivan P

    2017-09-26

    Superhydrophobic pillar arrays, which can generate the droplet pancake bouncing phenomenon with reduced liquid-solid contact time, have huge application prospects in anti-icing of aircraft wings from freezing rain. However, the previously reported pillar arrays, suitable for obtaining pancake bouncing, have a diameter ≤100 μm and height-diameter ratio >10, which are difficult to fabricate over a large area. Here, we have systematically studied the influence of the dimension of the superhydrophobic pillar arrays on the bouncing dynamics of water droplets. We show that the typical pancake bouncing with 57.8% reduction in contact time with the surface was observed on the superhydrophobic pillar arrays with 1.05 mm diameter, 0.8 mm height, and 0.25 mm space. Such pillar arrays with millimeter diameter and <1 height-diameter ratio can be easily fabricated over large areas. Further, a simple replication-spraying method was developed for the large-area fabrication of the superhydrophobic pillar arrays to induce pancake bouncing. No sacrificial layer was needed to reduce the adhesion in the replication processes. Since the bouncing dynamics were rather sensitive to the space between the pillars, a method to control the contact time, bouncing shape, horizontal bouncing direction, and reversible switch between pancake bouncing and conventional bouncing was realized by adjusting the inclination angle of the shape memory polymer pillars.

  6. Long-term Outcome of Multiple Small-diameter Drilling Decompression Combined with Hip Arthroscopy versus Drilling Alone for Early Avascular Necrosis of the Femoral Head

    PubMed Central

    Li, Ji; Li, Zhong-Li; Zhang, Hao; Su, Xiang-Zheng; Wang, Ke-Tao; Yang, Yi-Meng

    2017-01-01

    Background: Avascular necrosis of femoral head (AVNFH) typically presents in the young adults and progresses quickly without proper treatments. However, the optimum treatments for early stage of AVNFH are still controversial. This study was conducted to evaluate the therapeutic effects of multiple small-diameter drilling decompression combined with hip arthroscopy for early AVNFH compared to drilling alone. Methods: This is a nonrandomized retrospective case series study. Between April 2006 and November 2010, 60 patients (98 hips) with early stage AVNFH participated in this study. The patients underwent multiple small-diameter drilling decompression combined with hip arthroscopy in 26 cases/43 hips (Group A) or drilling decompression alone in 34 cases/55 hips (Group B). Patients were followed up at 6, 12, and 24 weeks, and every 6 months thereafter. Radiographs were taken at every follow-up, Harris scores were recorded at the last follow-up, the paired t-test was used to compare the postoperative Harris scores. Surgery effective rate of the two groups was compared using the Chi-square test. Results: All patients were followed up for an average of 57.6 months (range: 17–108 months). Pain relief and improvement of hip function were assessed in all patients at 6 months after the surgery. At the last follow-up, Group A had better outcome with mean Harris’ scores improved from 68.23 ± 11.37 to 82.07 ± 2.92 (t = −7.21, P = 0.001) than Group B with mean Harris’ scores improved from 69.46 ± 9.71 to 75.79 ± 4.13 (t = –9.47, P = 0.037) (significantly different: t = –2.54, P = 0.017). The total surgery effective rate was also significantly different between Groups A and B (86.0% vs. 74.5%; χ2 = 3.69, P = 0.02). Conclusion: For early stage of AVNFH, multiple small-diameter drilling decompression combined with hip arthroscopy is more effective than drilling decompression alone. PMID:28584206

  7. A see-through holographic head-mounted display with the large viewing angle

    NASA Astrophysics Data System (ADS)

    Chen, Zhidong; sang, Xinzhu; Lin, Qiaojun; Li, Jin; Yu, Xunbo; Gao, Xin; Yan, Binbin; Wang, Kuiru; Yu, Chongxiu; Xie, Songlin

    2017-02-01

    A novel solution for the large view angle holographic head-mounted display (HHMD) is presented. Divergent light is used for the hologram illumination to construct a large size three-dimensional object outside the display in a short distance. A designed project-type lens with large numerical aperture projects the object constructed by the hologram to its real location. The presented solution can realize a compact HHMD system with a large field of view. The basic principle and the structure of the system are described. An augmented reality (AR) prototype with the size of 50 mm×40 mm and the view angle above 60° is demonstrated.

  8. A reference pelton turbine - design and efficiency measurements

    NASA Astrophysics Data System (ADS)

    Solemslie, Bjørn W.; Dahlhaug, Ole G.

    2014-03-01

    The Pelton turbine has been subject to a varying degree of research interest since the debut of the technology over a century ago. Despite its age there are gaps in the knowledge concerning the flow mechanisms effecting the flow through the turbine. A Pelton turbine has been designed at the Waterpower Laboratory at NTNU. This has been done in connection to a Ph.D. project focusing on the flow in Pelton turbine buckets. The design of the turbine has been conducted using in-house knowledge in addition to some comments from a turbine producer. To describe the geometry multiple Bezier curves were used and the design strategy aimed to give a smooth and continuous gradient along the main flow directions in the bucket. The turbine has been designed for the operational conditions of the Pelton test rig installed at the Waterpower Laboratory which is a horizontal single jet test rig with a jet diameter(ds) of 35 mm. The diameter(D) of the runner was set to 513 mm and the width(W) of a bucket 114 mm, leading to a D/W ratio of 4.5. Manufacturing of the turbine has been carried out in aluminium and the turbine has undergone efficiency testing and visual inspection during operation at a head of 70 m. The turbine did not performed as expected and the maximum efficiency was found to be 77.75%. The low efficiency is mainly caused by a large amount of water leaving the bucket through the lip and hence transferring close to zero of its energy to the shaft. The reason for the large lip loss is discussed and two possible causes are found; the jet is located too close to the lip, and the inner surface of the bucket does not lead the water away from the lip. The turbine geometry and all data from both measurements and simulations will be available upon request in an effort to increase the amount of available data concerning Pelton turbines.

  9. Electron microscopy observations on testis and spermatozoa of Leptodactylus chaquensis (Anura, Leptodactylidae).

    PubMed

    Iruzubieta Villagra, Lucrecia; Ramos, Inés; Cisint, Susana; Crespo, Claudia A; Fernández, Silvia N

    2018-02-01

    Scanning and transmission electron microscopy were used to investigate the fine structure of the testis and spermatozoa of toad Leptodactylus chaquensis. Our observations indicate that germinal compartment contains Sertoli (SC) and germ cells. The tight junctions and desmosomes among SC indicate the existence of an hematotesticular barrier in charge of maintaining the differences in the composition of the germinal and interstitial compartments. During spermatogenesis, SC acts as a structural support for germ cells. Secondary spermatogonias, spermatocytes and spermatids are joined by cytoplasmic bridges that allow communication between cells in the same cyst. Spermatids at the subcellular level two well-defined morphological stages can be observed: primary spermatids are rounded cells with an acrosomal vesicle attached to the nucleus which has a diameter of about 4.39±0.36μm. Secondary spermatids are elongated with a nucleus of about 19.50±0.92μm in diameter and the acrosome and the axoneme are located in opposite poles of the cells. At the apical end of the spermatozoon we can observe a large arrowhead-shaped acrosome (6.26±0.28μm in length) that takes up about one third of the gamete head with 17.33±0.29μm in length. The proximal centriole is located in the nuclear fossa while the distal centriole gives rise to the flagellar axoneme. The flagellum exhibits a typical pattern of "9+2" and adjacent to it is the axial fiber, and an undulating membrane stretches between both structures. Transmission electron microscopy observations allowed us to produce a diagram of the structure of the spermatozoon of L. chaquensis. Leydig cells, located in the interstitial compartment, show scarce cytoplasm, mitochondria and large-sized lipid droplets which would provide the raw matter for the synthesis of steroid hormones. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. SU-F-I-05: Dose Symmetry for CTDI Equivalent Measurements with Limited Angle CBCT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Singh, V; McKenney, S; Sunde, P

    Purpose: CTDI measurements, useful for characterizing the x-ray output for multi-detector CT (MDCT), require a 360° rotation of the gantry; this presents a problem for cone beam CT (CBCT) due to its limited angular rotation. The purpose of this work is to demonstrate a methodology for overcoming this limited angular rotation so that CTDI measurements can also be made on CBCT systems making it possible to compare the radiation output from both types of system with a common metric. Methods: The symmetry of the CTDI phantom allows a 360° CTDI measurement to be replaced with two 180° measurements. A pencilmore » chamber with a real-time digitizer was placed at the center of the head phantom (16 cm, PMMA) and the resulting exposure measurement from a 180° acquisition was doubled. A pair of edge measurements, each obtained with the gantry passing through the same 180 arc, was obtained with the pencil chamber at opposite edges of the diameter of the phantom and then summed. The method was demonstrated on a clinical CT scanner (Philips, Brilliance6) and then implemented on an interventional system (Siemens, Axiom Artis). Results: The equivalent CTDI measurement agreed with the conventional CTDI measurement within 8%. The discrepancy in the two measurements is largely attributed to uncertainties in cropping the waveform to a 180°acquisition. (Note: Because of the reduced fan angle in the CBCT, CTDI is not directly comparable to MDCT values when a 32 cm phantom is used.) Conclusion: The symmetry-based CTDI measurement is an equivalent measurement to the conventional CTDI measurement when the fan angle is large enough to encompass the phantom diameter. This allows a familiar metric of radiation output to be employed on systems with a limited angular rotation.« less

  11. Design of a frequency domain instrument for simultaneous optical tomography and magnetic resonance imaging of small animals

    NASA Astrophysics Data System (ADS)

    Masciotti, James M.; Rahim, Shaheed; Grover, Jarrett; Hielscher, Andreas H.

    2007-02-01

    We present a design for frequency domain instrument that allows for simultaneous gathering of magnetic resonance and diffuse optical tomographic imaging data. This small animal imaging system combines the high anatomical resolution of magnetic resonance imaging (MRI) with the high temporal resolution and physiological information provided by diffuse optical tomography (DOT). The DOT hardware comprises laser diodes and an intensified CCD camera, which are modulated up to 1 GHz by radio frequency (RF) signal generators. An optical imaging head is designed to fit inside the 4 cm inner diameter of a 9.4 T MRI system. Graded index fibers are used to transfer light between the optical hardware and the imaging head within the RF coil. Fiducial markers are integrated into the imaging head to allow the determination of the positions of the source and detector fibers on the MR images and to permit co-registration of MR and optical tomographic images. Detector fibers are arranged compactly and focused through a camera lens onto the photocathode of the intensified CCD camera.

  12. Selective evaporation of focusing fluid in two-fluid hydrodynamic print head.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Keicher, David M.; Cook, Adam W.

    The work performed in this project has demonstrated the feasibility to use hydrodynamic focusing of two fluid steams to create a novel micro printing technology for electronics and other high performance applications. Initial efforts focused solely on selective evaporation of the sheath fluid from print stream provided insight in developing a unique print head geometry allowing excess sheath fluid to be separated from the print flow stream for recycling/reuse. Fluid flow models suggest that more than 81 percent of the sheath fluid can be removed without affecting the print stream. Further development and optimization is required to demonstrate this capabilitymore » in operation. Print results using two-fluid hydrodynamic focusing yielded a 30 micrometers wide by 0.5 micrometers tall line that suggests that the cross-section of the printed feature from the print head was approximately 2 micrometers in diameter. Printing results also demonstrated that complete removal of the sheath fluid is not necessary for all material systems. The two-fluid printing technology could enable printing of insulated conductors and clad optical interconnects. Further development of this concept should be pursued.« less

  13. Unconstrained tripolar hip implants: effect on hip stability.

    PubMed

    Guyen, Olivier; Chen, Qing Shan; Bejui-Hugues, Jacques; Berry, Daniel J; An, Kai-Nan

    2007-02-01

    Tripolar implants were developed to treat unstable total hip arthroplasties. However, there is limited confirmation that they achieve this purpose despite their increasing use. Because they have a larger effective head size, these implants are expected to increase range of motion to impingement and improve stability in situations at risk for impingement compared with conventional implants. We assessed the range of motion to impingement using a tripolar implant mounted to an automated hip simulator using 22.2-mm and 28-mm femoral head sizes. The 22 and 28-mm tripolar implants provided increases of 30.5 degrees in flexion, 15.4 degrees in adduction, and 22.4 degrees in external rotation compared with the conventional 22.2-mm femoral head diameter implant. At the critical position of 90 degrees hip flexion, there was an increase of 45.2 degrees in internal rotation. At 0 degrees and 30 degrees external rotation, extension increases were 18.8 degrees and 7.8 degrees, respectively. Bony impingement was the limiting factor. Tripolar implants increased the arc of motion before impingement in positions at risk for dislocation and are expected to provide greater stability.

  14. Optimum Design of a Ceramic Tensile Creep Specimen Using a Finite Element Method

    PubMed Central

    Wang, Z.; Chiang, C. K.; Chuang, T.-J.

    1997-01-01

    An optimization procedure for designing a ceramic tensile creep specimen to minimize stress concentration is carried out using a finite element method. The effect of pin loading and the specimen geometry are considered in the stress distribution calculations. A growing contact zone between the pin and the specimen has been incorporated into the problem solution scheme as the load is increased to its full value. The optimization procedures are performed for the specimen, and all design variables including pinhole location and pinhole diameter, head width, neck radius, and gauge length are determined based on a set of constraints imposed on the problem. In addition, for the purpose of assessing the possibility of delayed failure outside the gage section, power-law creep in the tensile specimen is considered in the analysis. Using a particular grade of advanced ceramics as an example, it is found that if the specimen is not designed properly, significant creep deformation and stress redistribution may occur in the head of the specimen resulting in undesirable (delayed) head failure of the specimen during the creep test. PMID:27805126

  15. Panoramic attitude sensor for Radio Astronomy Explorer B

    NASA Technical Reports Server (NTRS)

    Thomsen, R.

    1973-01-01

    An instrument system to acquire attitude determination data for the RAE-B spacecraft was designed and built. The system consists of an electronics module and two optical scanner heads. Each scanner head has an optical scanner with a field of view of 0.7 degrees diameter which scans the sky and measures the position of the moon, earth and sun relative to the spacecraft. This scanning is accomplished in either of two modes. When the spacecraft is spinning, the scanner operates in spherical mode, with the spacecraft spin providing the slow sweep of lattitude to scan the entire sky. After the spacecraft is placed in lunar orbit and despun, the scanner will operate in planar mode, advancing at a rate of 5.12 seconds per revolution in a fixed plane parallel to the spacecraft Z axis. This scan will cross and measure the moon horizons with every revolution. Each scanner head also has a sun slit which is aligned parallel to the spin axis of the spacecraft and which provides a sun pulse each revolution of the spacecraft. The electronics module provides the command and control, data processing and housekeeping functions.

  16. High Slew-Rate Head-Only Gradient for Improving Distortion in Echo Planar Imaging: Preliminary Experience

    PubMed Central

    Tan, Ek T.; Lee, Seung-Kyun; Weavers, Paul T.; Graziani, Dominic; Piel, Joseph E.; Shu, Yunhong; Huston, John; Bernstein, Matt A.; Foo, Thomas K.F.

    2016-01-01

    Purpose To investigate the effects on echo planar imaging (EPI) distortion of using high gradient slew rates (SR) of up to 700 T/m/s for in-vivo human brain imaging, with a dedicated, head-only gradient coil. Materials and Methods Simulation studies were first performed to determine the expected echo spacing and distortion reduction in EPI. A head gradient of 42-cm inner diameter and with asymmetric transverse coils was then installed in a whole-body, conventional 3T MRI system. Human subject imaging was performed on five subjects to determine the effects of EPI on echo spacing and signal dropout at various gradient slew rates. The feasibility of whole-brain imaging at 1.5 mm-isotropic spatial resolution was demonstrated with gradient-echo and spin-echo diffusion-weighted EPI. Results As compared to a whole-body gradient coil, the EPI echo spacing in the head-only gradient coil was reduced by 48%. Simulation and in vivo results, respectively, showed up to 25-26% and 19% improvement in signal dropout. Whole-brain imaging with EPI at 1.5 mm spatial resolution provided good whole-brain coverage, spatial linearity, and low spatial distortion effects. Conclusion Our results of human brain imaging with EPI using the compact head gradient coil at slew rates higher than in conventional whole-body MR systems demonstrate substantially improved image distortion, and point to a potential for benefits to non-EPI pulse sequences. PMID:26921117

  17. Duodenum-preserving resection and Roux-en-Y pancreatic jejunostomy in benign pancreatic head tumors.

    PubMed

    Yuan, Chun-Hui; Tao, Ming; Jia, Yi-Mu; Xiong, Jing-Wei; Zhang, Tong-Lin; Xiu, Dian-Rong

    2014-11-28

    This study was conducted to explore the feasibility of partial pancreatic head resection and Roux-en-Y pancreatic jejunostomy for the treatment of benign tumors of the pancreatic head (BTPH). From November 2006 to February 2009, four patients (three female and one male) with a mean age of 34.3 years (range: 21-48 years) underwent partial pancreatic head resection and Roux-en-Y pancreatic jejunostomy for the treatment of BTPH (diameters of 3.2-4.5 cm) using small incisions (5.1-7.2 cm). Preoperative symptoms include one case of repeated upper abdominal pain, one case of drowsiness and two cases with no obvious preoperative symptoms. All four surgeries were successfully performed. The mean operative time was 196.8 min (range 165-226 min), and average blood loss was 138.0 mL (range: 82-210 mL). The mean postoperative hospital stay was 7.5 d (range: 7-8 d). In one case, the main pancreatic duct was injured. Pathological examination confirmed that one patient suffered from mucinous cystadenoma, one exhibited insulinoma, and two patients had solid-pseudopapillary neoplasms. There were no deaths or complications observed during the perioperative period. All patients had no signs of recurrence of the BTPH within a follow-up period of 48-76 mo and had good quality of life without diabetes. Partial pancreatic head resection with Roux-en-Y pancreatic jejunostomy is feasible in selected patients with BTPH.

  18. Juvenile xanthogranuloma: a case report and review of the literature.

    PubMed

    Pajaziti, Laura; Hapçiu, Syzana Rexhepi; Pajaziti, Artina

    2014-03-26

    Juvenile xanthogranuloma is a rare disorder which may be present at birth, or appears in infancy. It can also occur in adults of all ages; appears with lesions that may be solitary or multiple nodules several millimeters in diameter. The predilection sites are head and neck, but it may occur on the extremities and trunk also. There can also be involved internal organs such as lung, kidney, gastrointestinal tract, etc. The most frequent extracutaneous location is the eye. We report a case of juvenile xanthogranuloma in a male child with onset in the fourth month of life. He presented with a nodule 8 millimeters in diameter, tan-orange in color, ulcerated in the centre, located on the left corner of the left eye. A biopsy without total excision was performed. After the biopsy, the nodule enlarged to 1.5 cm in diameter and became haemorrhagic. The histologic evaluation and immunohistochemistry analysis resulted in the diagnosis of juvenile xanthogranuloma. For aesthetic reasons the nodule was removed by surgical resection. Juvenile xanthogranuloma is on a spectrum of histiocytic disorders, which is necessary to differentiate from maligniances in childhood by biopsy.

  19. Automated fibre optic instrumentation for the William Herschel Telescope

    NASA Astrophysics Data System (ADS)

    Parry, Ian R.; Lewis, Ian J.

    1990-07-01

    The design and operation of the automated optical-fiber positioning system used for spectroscopic observations at the Cassegrain focus of the 4.2-m William Herschel Telescope (WHT) at Observatorio del Roque de los Muchachos are described. The system is a modified version of the Autofib positioner for the AAT and employs 64 spectroscopic fibers and 8 guide fiber bundles arranged to form a 17-arcmin-diameter field. The fibers are 1-m-long polyimide-coated high-OH silica, with core diameter 260 microns and outer diameter 315 microns, and a 1.2-mm side-length microprism is cemented to the end of each fiber or (7-fiber) guide bundle. The fibers are positioned one at a time by a pick-and-place robot assembly, and a viewing head permitting simultaneous observation of the back-illuminated fiber and the object it is trying to acquire is provided. This prototype Cassegrain-focus system is being studied to aid in the development of a more accurate fiber positioner for use at the prime focus of the WHT.

  20. [Effects of anteriolateral thigh perforator flap and fascia lata transplantation in combination with computed tomography angiography on repair of electrical burn wounds of head with skull exposure and necrosis].

    PubMed

    Li, X Q; Wang, X; Han, Y L; Ji, G; Chen, Z H; Zhang, J; Zhu, J P; Duan, J X; He, Y J; Yang, X M; Liu, W J

    2018-05-20

    Objective: To explore the effects of anteriolateral thigh perforator flap and fascia lata transplantation in combination with computed tomography angiography (CTA) on repair of electrical burn wounds of head with skull exposure and necrosis. Methods: Seven patients with head electrical burns accompanied by skull exposure and necrosis were admitted to our burn center from March 2016 to December 2017. Head CTA was performed before the operation. The diameters of the facial artery and vein or the superficial temporal artery and vein were measured, and their locations were marked on the body surface. Preoperative CTA for flap donor sites in lower extremities were also performed to track the descending branch of the lateral circumflex femoral artery with the similar diameter as the recipient vessels on the head, and their locations were marked on the body surface. Routine wound debridement and skull drilling were performed successively. The size of the wounds after debridement ranged from 12 cm×8 cm to 20 cm×12 cm, and the areas of skull exposure ranged from 8 cm×6 cm to 15 cm×10 cm. Anteriolateral thigh perforator flaps with areas from 13 cm×9 cm to 21 cm×13 cm containing 5-10 cm long vascular pedicles were designed and dissected accordingly. The fascia lata under the flap with area from 5 cm×2 cm to 10 cm×3 cm was dissected according to the length of vascular pedicle. The fascia lata was transplanted to cover the exposed skull, and the anteriolateral thigh perforator flap was transplanted afterwards. The descending branch of the lateral circumflex femoral artery and its accompanying vein of the flap were anastomosed with superficial temporal artery and vein or facial artery and vein before the suture of flap. The flap donor sites were covered by intermediate split-thickness skin graft collected from contralateral thigh or abdomen. Results: The descending branch of the lateral circumflex femoral artery and its accompanying vein were anastomosed with superficial temporal artery and vein in six patients, while those with facial artery and vein in one patient. All the flaps survived after the operation, and no vascular crisis was observed. Wound healing was satisfactory. One patient was lost to follow up. Six patients were followed up for 6 to 10 months. The patients were bald in the head operation area with acceptable appearance. No psychiatric symptom such as headache or epileptic seizure was reported. The flap donor sites were normal in appearance. The muscle strength of the lower extremities all reached grade V. The sensation and movement of the lower extremities were normal. Conclusions: Anterolateral thigh perforator flap with fascia lata transplantation can effectively repair electrical burn wounds of head with skull exposure and necrosis. The fascia lata can be used to protect the vascular pedicle of flaps, which is beneficial to the survival of the flap. Preoperative head and lower extremities CTA can provide reference for intraoperative vascular exploration in donor site and recipient area, so as to shorten operation time.

  1. Diameter Effect Curve and Detonation Front Curvature Measurements for ANFO

    NASA Astrophysics Data System (ADS)

    Catanach, R. A.; Hill, L. G.

    2002-07-01

    Diameter effect and front curvature measurements are reported for rate stick experiments on commercially available prilled ANFO (ammonium-nitrate/fuel-oil) at ambient temperature. The shots were fired in paper tubes so as to provide minimal confinement. Diameters ranged from 77 mm (approximately failure diameter) to 205 mm, with the tube length being ten diameters in all cases. Each detonation wave shape was fit with an analytic form, from which the local normal velocity Dn, and local total curvature kappa, were generated as a function of radius R, then plotted parametrically to generate a Dn(kappa) function. The observed behavior deviates substantially from that of previous explosives, for which curves for different diameters overlay well for small kappa but diverge for large kappa, and for which kappa increases monotonically with R. For ANFO, we find that Dn(kappa) curves for individual sticks 1) show little or no overlap--with smaller sticks lying to the right of larger ones, 2) exhibit a large velocity deficit with little kappa variation, and 3) reach a peak kappa at an intermediate R.

  2. Exogenous lysophospholipids with large head groups perturb clathrin-mediated endocytosis.

    PubMed

    Ailte, Ieva; Lingelem, Anne Berit D; Kvalvaag, Audun S; Kavaliauskiene, Simona; Brech, Andreas; Koster, Gerbrand; Dommersnes, Paul G; Bergan, Jonas; Skotland, Tore; Sandvig, Kirsten

    2017-03-01

    In this study, we have investigated how clathrin-dependent endocytosis is affected by exogenously added lysophospholipids (LPLs). Addition of LPLs with large head groups strongly inhibits transferrin (Tf) endocytosis in various cell lines, while LPLs with small head groups do not. Electron and total internal reflection fluorescence microscopy (EM and TIRF) reveal that treatment with lysophosphatidylinositol (LPI) with the fatty acyl group C18:0 leads to reduced numbers of invaginated clathrin-coated pits (CCPs) at the plasma membrane, fewer endocytic events per membrane area and increased lifetime of CCPs. Also, endocytosis of Tf becomes dependent on actin upon LPI treatment. Thus, our results demonstrate that one can regulate the kinetics and properties of clathrin-dependent endocytosis by addition of LPLs in a head group size- and fatty acyl-dependent manner. Furthermore, studies performed with optical tweezers show that less force is required to pull membrane tubules outwards from the plasma membrane when LPI is added to the cells. The results are in agreement with the notion that insertion of LPLs with large head groups creates a positive membrane curvature which might have a negative impact on events that require plasma membrane invagination, while it may facilitate membrane bending toward the cell exterior. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  3. Growth Retardation Of Chick Embryo Exposed To A Low Dose Of Electromagnetic Waves.

    PubMed

    Siddiqi, Najam; John C, Muthusami; Norrish, Mark; Heming, Thomas

    2016-01-01

    The objectives of this study were to explore the effects of low dose of the nonionizing (REW) emitted by a mobile phone on the development of chick embryo. one hundred and twenty chick fertilized eggs were equally divided into a control and an exposed group. Sixty fertilized eggs were placed in an egg incubator with a mobile phone (SAR US: 1.10W/kg (head) 0.47 W/kg body) in silent mode having vibration disable mode. Mobile was called for a total of 20 minutes in 24 hours. Twenty embryos each were sacrificed at day 5, 10 and 15, mortality, wet body weight, head to rump length, eye diameter and morphological changes were noted. The control group, 60 eggs were incubated in the same conditions, having removed the phone. No mortality was noted. The experimental group exposed to REW showed subcutaneous haemorrhagic areas and significant growth retardation at day 10 as evidence by smaller eye diameter, wet weight and CR length than the control group. There were no significant growth differences at either day 5 or at day 15. Electromagnetic waves emitted from mobile phones even though for a very short duration of 20 minutes per day have affected the growth of the chick embryo at day 10 of incubation, Hence exposure of these waves are not 100% safe.

  4. Advanced UVOIR Mirror Technology Development (AMTD) for Very Large Space Telescopes

    NASA Technical Reports Server (NTRS)

    Postman, Marc; Soummer, Remi; Sivramakrishnan, Annand; Macintosh, Bruce; Guyon, Olivier; Krist, John; Stahl, H. Philip; Smith, W. Scott; Mosier, Gary; Kirk, Charles; hide

    2013-01-01

    AMTD partner Exelis developed & demonstrated a technique to manufacture a 400 mm thick substrate via stacking and fusing core structural elements to front and back faceplates; making a 40 cm cut-out of a 4 meter diameter 60 kilograms per square meter mirror. This new process offers a lower cost approach for manufacturing large-diameter high-stiffness mirrors.

  5. 78 FR 10134 - Welded Large Diameter Line Pipe From Japan: Final Results of the Expedited Second Sunset Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-13

    ... Pipe From Japan: Final Results of the Expedited Second Sunset Review of the Antidumping Duty Order... antidumping duty order on welded large diameter line pipe (line pipe) from Japan pursuant to section 751(c) of... Department initiated the sunset review of the antidumping duty order on line pipe from Japan pursuant to...

  6. Experimental study of operation performance for hydrocarbon fuel pump with low specific speed

    NASA Astrophysics Data System (ADS)

    Wu, Xianyu; Yang, Jun; Jin, Xuan

    2017-10-01

    In this paper, a small flow rate hydrocarbon turbine pump was used to pressurize the fuel supply system of scramjet engine. Some experiments were carried out to investigate the characteristics of turbine pump driven by nitrogen or combustion gas under different operating conditions. A experimental database with regard to the curves of the rotational speed, mass flow rate and net head with regard to centrifugal pump were plotted. These curves were represented as functions of the pressure and temperature at turbine inlet/outlet and the throttle diameter at downstream of centrifugal pump. A sensitivity study has been carried out based on design of experiments. The experimental was employed to analyze net head of centrifugal and throttle characteristics. The research results can accumulate foundations for the close loop control system of turbine pump.

  7. The impact of surface and geometry on coefficient of friction of artificial hip joints.

    PubMed

    Choudhury, Dipankar; Vrbka, Martin; Mamat, Azuddin Bin; Stavness, Ian; Roy, Chanchal K; Mootanah, Rajshree; Krupka, Ivan

    2017-08-01

    Coefficient of friction (COF) tests were conducted on 28-mm and 36-mm-diameter hip joint prostheses for four different material combinations, with or without the presence of Ultra High Molecular Weight Polyethylene (UHMWPE) particles using a novel pendulum hip simulator. The effects of three micro dimpled arrays on femoral head against a polyethylene and a metallic cup were also investigated. Clearance played a vital role in the COF of ceramic on polyethylene and ceramic on ceramic artificial hip joints. Micro dimpled metallic femoral heads yielded higher COF against a polyethylene cup; however, with metal on metal prostheses the dimpled arrays significantly reduced the COF. In situ images revealed evidence that the dimple arrays enhanced film formation, which was the main mechanism that contributed to reduced friction. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Vortex systems on slender rotating bodies and their effect on the aerodynamic coefficients

    NASA Technical Reports Server (NTRS)

    Fiechter, M.

    1986-01-01

    The turbulent flow of rotational bodies up to a length of 20 diameters with various head shapes and cylindrical tails was examined in the subsonic wind tunnel with the Mach number of M = 0.1. At angles of incidence lower than 30 degrees, a pair of symmetrical eddies rests stationary from head to tail on the trailing side, very close to the body. At angles between 30 and 60 degrees, the stationary eddies are asymmetrically pushed off. Between 60 and 90 degrees, the eddies detach themselves in an instationary manner. This includes, for example, the turbulent flow at the start-up of flying bodies in the presence of lateral winds. The results of measurments obtained by Mello at M = 2, an impulse method, and the cross flow theory according to Allen are used for comparison.

  9. Portable X-Ray, K-Edge Heavy Metal Detector

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fricke, V.

    The X-Ray, K-Edge Heavy Metal Detection System was designed and built by Ames Laboratory and the Center for Nondestructive Evaluation at Iowa State University. The system uses a C-frame inspection head with an X-ray tube mounted on one side of the frame and an imaging unit and a high purity germanium detector on the other side. the inspection head is portable and can be easily positioned around ventilation ducts and pipes up to 36 inches in diameter. Wide angle and narrow beam X-ray shots are used to identify the type of holdup material and the amount of the contaminant. Precisemore » assay data can be obtained within minutes of the interrogation. A profile of the containerized holdup material and a permanent record of the measurement are immediately available.« less

  10. Heat-assisted magnetic recording of bit-patterned media beyond 10 Tb/in2

    NASA Astrophysics Data System (ADS)

    Vogler, Christoph; Abert, Claas; Bruckner, Florian; Suess, Dieter; Praetorius, Dirk

    2016-03-01

    The limits of areal storage density that is achievable with heat-assisted magnetic recording are unknown. We addressed this central question and investigated the areal density of bit-patterned media. We analyzed the detailed switching behavior of a recording bit under various external conditions, allowing us to compute the bit error rate of a write process (shingled and conventional) for various grain spacings, write head positions, and write temperatures. Hence, we were able to optimize the areal density yielding values beyond 10 Tb/in2. Our model is based on the Landau-Lifshitz-Bloch equation and uses hard magnetic recording grains with a 5-nm diameter and 10-nm height. It assumes a realistic distribution of the Curie temperature of the underlying material, grain size, as well as grain and head position.

  11. Simulation of hydrocephalus condition in infant head

    NASA Astrophysics Data System (ADS)

    Wijayanti, Erna; Arif, Idam

    2014-03-01

    Hydrocephalus is a condition of an excessive of cerebrospinal fluid in brain. In this paper, we try to simulate the behavior of hydrocephalus conditions in infant head by using a hydro-elastic model which is combined with orthotropic elastic skull and with the addition of suture that divide the skull into two lobes. The model then gives predictions for the case of stenosis aqueduct by varying the cerebral aqueduct diameter, time constant and brain elastic modulus. The hydrocephalus condition which is shown by the significant value of ventricle displacement, as the result shows, is occurred when the aqueduct is as resistant as brain parenchyma for the flow of cerebrospinal fluid. The decrement of brain elastic modulus causes brain parenchyma displacement value approach ventricle displacement value. The smaller of time constant value causes the smaller value of ventricle displacement.

  12. Real-time ultrasonography as a monitoring technique for interstitial Nd:YAG laser treatment of voluminous hemangiomas and vascular malformations

    NASA Astrophysics Data System (ADS)

    Werner, Jochen A.; Gottschlich, Stefan; Lippert, Burkard M.; Folz, Benedikt J.

    1998-01-01

    Voluminous vascular anomalies of the head and neck region are still treated with conventional surgery although Neodymium:Yttrium-Aluminum-Garnet (Nd:YAG) laser therapy is an effective treatment method. One hundred thirty give patients with voluminous hemangiomas and vascular malformations were treated with interstitial Nd:YAG laser therapy, partly complemented by a non-contact mode Nd:YAG laser light application. The vascular tumors had a diameter of more than 3 cm in two or all three dimensions. Treatment was carried out under ultrasound and manual control. Nearly 60% of the patients showed a complete clinical regression of the vascular tumor, a third of the patients had a partial regression and were satisfied with the treatment outcome. Four patients were treated unsuccessfully with the laser and three of them subsequently underwent conventional surgery. Only 10 patients showed cosmetic and functional deficits. These results on the interstitial Nd:YAG laser therapy of voluminous hemangiomas and vascular malformations in a large patient group demonstrated the high effectiveness of this novel and innovative therapy modality.

  13. Diffractive beam shaping for enhanced laser polymer welding

    NASA Astrophysics Data System (ADS)

    Rauschenberger, J.; Vogler, D.; Raab, C.; Gubler, U.

    2015-03-01

    Laser welding of polymers increasingly finds application in a large number of industries such as medical technology, automotive, consumer electronics, textiles or packaging. More and more, it replaces other welding technologies for polymers, e. g. hot-plate, vibration or ultrasonic welding. At the same rate, demands on the quality of the weld, the flexibility of the production system and on processing speed have increased. Traditionally, diode lasers were employed for plastic welding with flat-top beam profiles. With the advent of fiber lasers with excellent beam quality, the possibility to modify and optimize the beam profile by beam-shaping elements has opened. Diffractive optical elements (DOE) can play a crucial role in optimizing the laser intensity profile towards the optimal M-shape beam for enhanced weld seam quality. We present results on significantly improved weld seam width constancy and enlarged process windows compared to Gaussian or flat-top beam profiles. Configurations in which the laser beam diameter and shape can be adapted and optimized without changing or aligning the laser, fiber-optic cable or optical head are shown.

  14. Prenatal development in fishers (Martes pennanti)

    USGS Publications Warehouse

    Frost, H.C.; Krohn, W.B.; Bezembluk, E.A.; Lott, R.; Wallace, C.R.

    2005-01-01

    We evaluated and quantified prenatal growth of fishers (Martes pennanti) using ultrasonography. Seven females gave birth to 21 kits. The first identifiable embryonic structures were seen 42 d prepartum; these appeared to be unimplanted blastocysts or gestational sacs, which subsequently implanted in the uterine horns. Maternal and fetal heart rates were monitored from first detection to birth. Maternal heart rates did not differ among sampling periods, while fetal hearts rates increased from first detection to birth. Head and body differentiation, visible limbs and skeletal ossification were visible by 30, 23 and 21 d prepartum, respectively. Mean diameter of gestational sacs and crown-rump lengths were linearly related to gestational age (P < 0.001). Biparietal and body diameters were also linearly related to gestational age (P < 0.001) and correctly predicted parturition dates within 1-2 d. ?? 2004 Elsevier Inc. All rights reserved.

  15. Kinetics modeling of the drying of sunflower stem (Helianthus annuus L.) in a forced convection tunnel

    NASA Astrophysics Data System (ADS)

    López, R.; Vaca, M.; Terres, H.; Lizardi, A.; Morales, J.; Flores, J.; Chávez, S.

    2015-01-01

    The sunflower is an annual plant native to the Americas. It possesses a large inflorescence (flowering head), and its name is derived from the flower's shape and image, which is often used to capture the sun. The plant has a rough, broad, hairy stem, coarsely toothed, with rough leaves, and circular flower heads. The sunflower seeds are appreciated for their oil, which has become a widespread cooking ingredient. Leaves of the sunflower can be used as cattle feed, while the stems contain a fiber that may be used in paper production. Recently this flower has been used in phytoremediation of soils, contaminated with heavy metals. Sunflower has been probed as an efficient phytoextractor of chromium, lead, aluminum, zinc, cadmium from soil. In this work we present the experimental results of the drying of the sunflower stem, cut in 100 mm longitudinal sections, with diameters in the range of 11-18 mm. The aim was to obtain a dry and easy-to-handle final product, since these plants were originally cultivated in order to extract heavy metals from a polluted soil. The dried stems could then be easily confined or sent to recycle premises to concentrate the metals. The drying process was done in forced convection within a hot air tunnel. The used temperature was 60 °C, the velocity of air was 3 m/s and the required times were 8 hours. The initial average wet mass was 28 g and the final value was 5 g, resulting in the aimed product.

  16. Obstetric risk indicators for labour dystocia in nulliparous women: A multi-centre cohort study

    PubMed Central

    Kjærgaard, Hanne; Olsen, Jørn; Ottesen, Bent; Nyberg, Per; Dykes, Anna-Karin

    2008-01-01

    Background In nulliparous women dystocia is the most common obstetric problem and its etiology is largely unknown. The frequency of augmentation and cesarean delivery related to dystocia is high although it is not clear if a slow progress justifies the interventions. Studies of risk factors for dystocia often do not provide diagnostic criteria for the diagnosis. The aim of the present study was to identify obstetric and clinical risk indicators of dystocia defined by strict and explicit criteria. Methods A multi-centre population based cohort study with prospectively collected data from 2810 nulliparous women in term spontaneous labour with a singleton infant in cephalic presentation. Data were collected by self-administered questionnaires and clinical data-records. Logistic regression analyses were used to estimate adjusted Odds Ratios (OR) and 95% confidence intervals (CI) are given. Results The following characteristics, present at admission to hospital, were associated with dystocia during labour (OR, 95% CI): dilatation of cervix < 4 cm (1.63, 1.38–1.92), tense cervix (1.31, 1.04–1.65), thick lower segment (1.32, 1.09–1.61), fetal head above the inter-spinal diameter (2.29, 1.80–2.92) and poor fetal head-to-cervix contact (1.83, 1.31–2.56). The use of epidural analgesia (5.65, 4.33–7.38) was also associated with dystocia. Conclusion Vaginal examinations at admission provide useful information on risk indicators for dystocia. The strongest risk indicator was use of epidural analgesia and if part of that is causal, it is of concern. PMID:18837972

  17. Magnetostriction measurement of a giant magnetoresistance film on a practical substrate covered by a shield layer

    NASA Astrophysics Data System (ADS)

    Okita, Kazuhiko; Ishiyama, Kazushi; Miura, Hideo

    2012-04-01

    Magnetostriction constant of a magnetic thin film is conventionally measured by detecting the deformation of a coupon sample that consists of the magnetic film deposited on a thin glass substrate (e.g., cover glass of size 10 mm × 25 mm) under an applied field using a laser beam [A. C. Tam and H. Schroeder, J. Appl. Phys. 64, 5422 (1988)]. This method, however, cannot be applied to films deposited on actual large-size substrates (wafers) with diameter from 3 to 6 in. or more. In a previous paper [Okita et al., J. Phys.: Conf. Ser. 200, 112008 (2010)], the authors presented a method for measuring magnetostriction of a magnetic thin film deposited on an actual substrate by detecting the change of magnetic anisotropy field, Hk, under mechanical bending of the substrate. It was validated that the method is very effective for measuring the magnetostriction constant of a free layer on the actual substrate. However, since a Ni-Fe shield layer usually covers a magnetic head used for a hard disk drive, this shield layer disturbs the effective measurement of R-H curve under minor loop. Therefore, a high magnetic field that can saturate the magnetic material in the shield layer should be applied to the head in order to measure the magnetostriction constant of a pinned layer under the shield layer. In this paper, this method was applied to the measurement of the magnetostriction constant of a pinned layer under the shield layer by using a high magnetic field up to 320 kA/m (4 kOe).

  18. Ab initio density functional theory investigation of crystalline bundles of polygonized single-walled silicon carbide nanotubes

    NASA Astrophysics Data System (ADS)

    Moradian, Rostam; Behzad, Somayeh; Chegel, Raad

    2008-11-01

    By using ab initio density functional theory, the structural characterizations and electronic properties of two large-diameter (13, 13) and (14, 14) armchair silicon carbide nanotube (SiCNT) bundles are investigated. Full structural optimizations show that the cross sections of these large-diameter SiCNTs in the bundles have a nearly hexagonal shape. The effects of inter-tube coupling on the electronic dispersions of large-diameter SiCNT bundles are demonstrated. By comparing the band structures of the triangular lattices of (14, 14) SiCNTs with nearly hexagonal and circular cross sections we found that the polygonization of the tubes in the bundle leads to a further dispersion of the occupied bands and an increase in the bandgap by 0.18 eV.

  19. Ab initio density functional theory investigation of crystalline bundles of polygonized single-walled silicon carbide nanotubes.

    PubMed

    Moradian, Rostam; Behzad, Somayeh; Chegel, Raad

    2008-11-19

    By using ab initio density functional theory, the structural characterizations and electronic properties of two large-diameter (13, 13) and (14, 14) armchair silicon carbide nanotube (SiCNT) bundles are investigated. Full structural optimizations show that the cross sections of these large-diameter SiCNTs in the bundles have a nearly hexagonal shape. The effects of inter-tube coupling on the electronic dispersions of large-diameter SiCNT bundles are demonstrated. By comparing the band structures of the triangular lattices of (14, 14) SiCNTs with nearly hexagonal and circular cross sections we found that the polygonization of the tubes in the bundle leads to a further dispersion of the occupied bands and an increase in the bandgap by 0.18 eV.

  20. High resolution macroscopy (HRMac) of the eye using nonlinear optical imaging

    NASA Astrophysics Data System (ADS)

    Winkler, Moritz; Jester, Bryan E.; Nien-Shy, Chyong; Chai, Dongyul; Brown, Donald J.; Jester, James V.

    2010-02-01

    Non-linear optical (NLO) imaging using femtosecond lasers provides a non-invasive means of imaging the structural organization of the eye through the generation of second harmonic signals (SHG). While NLO imaging is able to detect collagen, the small field of view (FoV) limits the ability to study how collagen is structurally organized throughout the larger tissue. To address this issue we have used computed tomography on optical and mechanical sectioned tissue to greatly expand the FoV and provide high resolution macroscopic (HRMac) images that cover the entire tissue (cornea and optic nerve head). Whole, fixed cornea (13 mm diameter) or optic nerve (3 mm diameter) were excised and either 1) embedded in agar and sectioned using a vibratome (200-300 um), or 2) embedded in LR White plastic resin and serially sectioned (2 um). Vibratome and plastic sections were then imaged using a Zeiss LSM 510 Meta and Chameleon femtosecond laser to generate NLO signals and assemble large macroscopic 3-dimensional tomographs with high resolution that varied in size from 9 to 90 Meg pixels per plane having a resolution of 0.88 um lateral and 2.0 um axial. 3-D reconstructions allowed for regional measurements within the cornea and optic nerve to quantify collagen content, orientation and organization over the entire tissue. We conclude that NLO based tomography to generate HRMac images provides a powerful new tool to assess collagen structural organization. Biomechanical testing combined with NLO tomography may provide new insights into the relationship between the extracellular matrix and tissue mechanics.

  1. Balitora chipkali, a new species of stone loach (Teleostei: Balitoridae) from the northern Western Ghats of India, with a note on the distribution of B. laticauda.

    PubMed

    Kumkar, Pradeep; Katwate, Unmesh; Raghavan, Rajeev; Dahanukar, Neelesh

    2016-07-14

    Balitora chipkali, a new species of stone loach, is described from the westward-flowing Astoli tributary of the Kali River system in the northern part of the Western Ghats, India. The species differs from its congeners in a combination of characters that includes: a single pair of maxillary barbels; a large eye, of diameter greater than 15% head length (HL); snout length less than 4 times eye diameter; gape of mouth less than 30% HL; upper lip with 9-12 papillae in first series and 3-8 papillae in second series; flattened body, of depth less than 15% standard length; caudal-peduncle length less than three times its depth, 66-68 lateral line scales, 11 caudal vertebrae excluding compound centrum, third infraorbital sensory canal tube straight; and a distinct color pattern with almost round 7 dorsal saddles not reaching lateral irregular crossbar markings. Balitora chipkali forms a monophyletic group with B. laticauda as its sister taxon in a phylogeny based on a concatenated cytochrome b (Cytb) and cytochrome oxidase subunit 1 (COI) gene fragments. Raw genetic distance between B. chipkali and B. laticauda was 1.9-2.2% based on COI and 3.4-4.3% based on Cytb partial gene sequences, which was far more than the intra-species variation in widely separated populations of B. laticauda. Based on molecular and morphological analysis, we also provide new locality records for B. laticauda and delimit its distribution to eastward-flowing tributaries of the Krishna River system in the northern Western Ghats.

  2. Unshrouded Centrifugal Turbopump Impeller Design Methodology

    NASA Technical Reports Server (NTRS)

    Prueger, George H.; Williams, Morgan; Chen, Wei-Chung; Paris, John; Williams, Robert; Stewart, Eric

    2001-01-01

    Turbopump weight continues to be a dominant parameter in the trade space for reduction of engine weight. Space Shuttle Main Engine weight distribution indicates that the turbomachinery make up approximately 30% of the total engine weight. Weight reduction can be achieved through the reduction of envelope of the turbopump. Reduction in envelope relates to an increase in turbopump speed and an increase in impeller head coefficient. Speed can be increased until suction performance limits are achieved on the pump or due to alternate constraints the turbine or bearings limit speed. Once the speed of the turbopump is set the impeller tip speed sets the minimum head coefficient of the machine. To reduce impeller diameter the head coefficient must be increased. A significant limitation with increasing head coefficient is that the slope of the head-flow characteristic is affected and this can limit engine throttling range. Unshrouded impellers offer a design option for increased turbopump speed without increasing the impeller head coefficient. However, there are several issues with regard to using an unshrouded impeller: there is a pump performance penalty due to the front open face recirculation flow, there is a potential pump axial thrust problem from the unbalanced front open face and the back shroud face, and since test data is very limited for this configuration, there is uncertainty in the magnitude and phase of the rotordynamic forces due to the front impeller passage. The purpose of the paper is to discuss the design of an unshrouded impeller and to examine the hydrodynamic performance, axial thrust, and rotordynamic performance. The design methodology will also be discussed. This work will help provide some guidelines for unshrouded impeller design.

  3. High-throughput and high-yield fabrication of uniaxially-aligned chitosan-based nanofibers by centrifugal electrospinning

    PubMed Central

    Erickson, Ariane E.; Edmondson, Dennis; Chang, Fei-Chien; Wood, Dave; Gong, Alex; Levengood, Sheeny Lan; Zhang, Miqin

    2016-01-01

    The inability to produce large quantities of nanofibers has been a primary obstacle in advancement and commercialization of electrospinning technologies, especially when aligned nanofibers are desired. Here, we present a high-throughput centrifugal electrospinning (HTP-CES) system capable of producing a large number of highly-aligned nanofiber samples with high-yield and tunable diameters. The versatility of the design was revealed when bead-less nanofibers were produced from copolymer chitosan/polycaprolactone (C-PCL) solutions despite variations in polymer blend composition or spinneret needle gauge. Compared to conventional electrospinning techniques, fibers spun with the HTP-CES not only exhibited superior alignment, but also better diameter uniformity. Nanofiber alignment was quantified using Fast Fourier Transform (FFT) analysis. In addition, a concave correlation between the needle diameter and resultant fiber diameter was identified. This system can be easily scaled up for industrial production of highly-aligned nanofibers with tunable diameters that can potentially meet the requirements for various engineering and biomedical applications. PMID:26428148

  4. Method for fabricating thin californium-containing radioactive source wires

    DOEpatents

    Gross, Ian G; Pierce, Larry A

    2006-08-22

    A method for reducing the cross-sectional diameter of a radioactive californium-containing cermet wire while simultaneously improving the wire diameter to a more nearly circular cross section. A collet fixture is used to reduce the wire diameter by controlled pressurization pulses while simultaneously improving the wire cross-sectional diameter. The method is especially suitable for use in hot cells for the production of optimized cermet brachytherapy sources that contain large amounts of radioactive californium-252.

  5. Heat flux limiting sleeves

    DOEpatents

    Harris, William G.

    1985-01-01

    A heat limiting tubular sleeve extending over only a portion of a tube having a generally uniform outside diameter, the sleeve being open on both ends, having one end thereof larger in diameter than the other end thereof and having a wall thickness which decreases in the same direction as the diameter of the sleeve decreases so that the heat transfer through the sleeve and tube is less adjacent the large diameter end of the sleeve than adjacent the other end thereof.

  6. Survivorship of raked and unraked trees through prescribed fires in conifer forests in northeastern California

    Treesearch

    William F. Laudenslayer; George N. Steger; Jonathan Arnold

    2008-01-01

    Large diameter, old trees are an important component of functioning forests, as they provide habitat for many wildlife species and add value to the scenery along roads and trails that cross our National Forests and Parks. Tree mortality, from prescribed or wild fire, is of great concern to forests managers, especially mortality of those of large diameter. Raking away...

  7. Uncertainty of large-area estimates of indicators of forest structural gamma diversity: A study based on national forest inventory data

    Treesearch

    Susanne Winter; Andreas Böck; Ronald E. McRoberts

    2012-01-01

    Tree diameter and height are commonly measured forest structural variables, and indicators based on them are candidates for assessing forest diversity. We conducted our study on the uncertainty of estimates for mostly large geographic scales for four indicators of forest structural gamma diversity: mean tree diameter, mean tree height, and standard deviations of tree...

  8. Multitemporal observations of identical active dust devils on Mars with the High Resolution Stereo Camera (HRSC) and Mars Orbiter Camera (MOC)

    NASA Astrophysics Data System (ADS)

    Reiss, D.; Zanetti, M.; Neukum, G.

    2011-09-01

    Active dust devils were observed in Syria Planum in Mars Observer Camera - Wide Angle (MOC-WA) and High Resolution Stereo Camera (HRSC) imagery acquired on the same day with a time delay of ˜26 min. The unique operating technique of the HRSC allowed the measurement of the traverse velocities and directions of motion. Large dust devils observed in the HRSC image could be retraced to their counterparts in the earlier acquired MOC-WA image. Minimum lifetimes of three large (avg. ˜700 m in diameter) dust devils are ˜26 min, as inferred from retracing. For one of these large dust devil (˜820 m in diameter) it was possible to calculate a minimum lifetime of ˜74 min based on the measured horizontal speed and the length of its associated dust devil track. The comparison of our minimum lifetimes with previous published results of minimum and average lifetimes of small (˜19 m in diameter, avg. min. lifetime of ˜2.83 min) and medium (˜185 m in diameter, avg. min. lifetime of ˜13 min) dust devils imply that larger dust devils on Mars are active for much longer periods of time than smaller ones, as it is the case for terrestrial dust devils. Knowledge of martian dust devil lifetimes is an important parameter for the calculation of dust lifting rates. Estimates of the contribution of large dust devils (>300-1000 m in diameter) indicate that they may contribute, at least regionally, to ˜50% of dust entrainment by dust devils into the atmosphere compared to the dust devils <300 m in diameter given that the size-frequency distribution follows a power-law. Although large dust devils occur relatively rarely and the sediment fluxes are probably lower compared to smaller dust devils, their contribution to the background dust opacity by dust devils on Mars could be at least regionally large due to their longer lifetimes and ability of dust lifting into high atmospheric layers.

  9. Morphological variation in head shape of pipefishes and seahorses in relation to snout length and developmental growth.

    PubMed

    Leysen, Heleen; Roos, Gert; Adriaens, Dominique

    2011-10-01

    The feeding apparatus of Syngnathidae, with its elongate tubular snout and tiny, toothless jaws, is highly specialized for performing fast and powerful pivot feeding. In addition, the prolonged syngnathid parental care probably enables the juveniles to be provided with a feeding apparatus that resembles the one in adults, both in morphology and function. In this study, a landmark-based geometric morphometric analysis was carried out on the head of syngnathid representatives in order to (1) examine to what degree pipefish shape variation is different from that of seahorses; (2) determine whether the high level of specialization reduces the amount of intraspecific morphological variation found within the family; and (3) elucidate whether or not important shape changes occur in the seahorse head during postrelease ontogeny. We found that (1) there is a significant shape difference between head shape of pipefish and seahorse: the main differences concern snout length and height, position and orientation of the pectoral fin base, and height of the head and opercular bone. We hypothesize that this might be related to different prey capture kinematics (long snout with little head rotation versus short snout with large head rotation) and to different body postures (in line with the head versus vertical with a tilted head) in pipefishes and seahorses; (2) both pipefishes and seahorses showed an inverse relation between relative snout length and intraspecific variation and although pipefishes show a large diversity in relative snout elongation, they are more constrained in terms of head shape; and (3) the head of juvenile Hippocampus reidi specimens still undergoes gradual shape changes after being expelled from the brood pouch. Ontogenetic changes include lowering of the snout and head but also differences in orientation of the preopercular bone and lowering of the snout tip. Copyright © 2011 Wiley-Liss, Inc.

  10. U-PHOS Project: Development of a Large Diameter Pulsating Heat Pipe Experiment on board REXUS 22

    NASA Astrophysics Data System (ADS)

    Nannipieri, P.; Anichini, M.; Barsocchi, L.; Becatti, G.; Buoni, L.; Celi, F.; Catarsi, A.; Di Giorgio, P.; Fattibene, P.; Ferrato, E.; Guardati, P.; Mancini, E.; Meoni, G.; Nesti, F.; Piacquadio, S.; Pratelli, E.; Quadrelli, L.; Viglione, A. S.; Zanaboni, F.; Mameli, M.; Baronti, F.; Fanucci, L.; Marcuccio, S.; Bartoli, C.; Di Marco, P.; Bianco, N.; Marengo, M.; Filippeschi, S.

    2017-01-01

    U-PHOS Project aims at analysing and characterising the behaviour of a large diameter Pulsating Heat Pipe (PHP) on board REXUS 22 sounding rocket. A PHP is a passive thermal control device where the heat is efficiently transported by means of the self-sustained oscillatory fluid motion driven by the phase change phenomena. Since, in milli-gravity conditions, buoyancy forces become less intense, the PHP diameter may be increased still maintaining the slug/plug typical flow pattern. Consequently, the PHP heat power capability may be increased too. U-PHOS aims at proving that a large diameter PHP effectively works in milli-g conditions by characterizing its thermal response during a sounding rocket flight. The actual PHP tube is made of aluminum (3 mm inner diameter, filled with FC-72), heated at the evaporator by a compact electrical resistance, cooled at the condenser by a Phase Change Material (PCM) embedded in a metallic foam. The tube wall temperatures are recorded by means of Fibre Bragg Grating (FBG) sensors; the local fluid pressure is acquired by means of a pressure transducer. The present work intends to report the actual status of the project, focusing in particular on the experiment improvements with respect to the previous campaign.

  11. Design and development of a large diameter high pressure fast acting propulsion valve and valve actuator

    NASA Technical Reports Server (NTRS)

    Srinivasan, K. V.

    1986-01-01

    The design and development of a large diameter high pressure quick acting propulsion valve and valve actuator is described. The valve is the heart of a major test facility dedicated to conducting full scale performance tests of aircraft landing systems. The valve opens in less than 300 milliseconds releasing a 46-centimeter- (18-in.-) diameter water jet and closes in 300 milliseconds. The four main components of the valve, i.e., valve body, safety shutter, high speed shutter, and pneumatic-hydraulic actuator, are discussed. This valve is unique and may have other aerospace and industrial applications.

  12. Design and Development of a Large Diameter, High Pressure, Fast Acting Propulsion Valve and Valve Actuator

    NASA Technical Reports Server (NTRS)

    Srinivasan, K. V.

    1986-01-01

    This paper describes the design and development of a large diameter high pressure quick acting propulsion valve and valve actuator. The valve is the heart of a major test facility dedicated to conducting full scale performance tests of aircraft landing gear systems. The valve opens in less than 300 milliseconds releasing a 46 cm (18 in) diameter water jet and closes in 300 milliseconds. The four main components of the valve, i.e., valve body, safety shutter, high speed shutter, and pneumatic-hydraulic actuator, are discussed. This valve is unique and may have other aerospace and industrial applications.

  13. Fabrication of aluminum-carbon composites

    NASA Technical Reports Server (NTRS)

    Novak, R. C.

    1973-01-01

    A screening, optimization, and evaluation program is reported of unidirectional carbon-aluminum composites. During the screening phase both large diameter monofilament and small diameter multifilament reinforcements were utilized to determine optimum precursor tape making and consolidation techniques. Difficulty was encountered in impregnating and consolidating the multifiber reinforcements. Large diameter monofilament reinforcement was found easier to fabricate into composites and was selected to carry into the optimization phase in which the hot pressing parameters were refined and the size of the fabricated panels was scaled up. After process optimization the mechanical properties of the carbon-aluminum composites were characterized in tension, stress-rupture and creep, mechanical fatigue, thermal fatigue, thermal aging, thermal expansion, and impact.

  14. Management of the high-order mode content in large (40 microm) core photonic bandgap Bragg fiber laser.

    PubMed

    Gaponov, D A; Février, S; Devautour, M; Roy, P; Likhachev, M E; Aleshkina, S S; Salganskii, M Y; Yashkov, M V; Guryanov, A N

    2010-07-01

    Very large-mode-area Yb(3+)-doped single-mode photonic bandgap (PBG) Bragg fiber oscillators are considered. The transverse hole-burning effect is numerically modeled, which helps properly design the PBG cladding and the Yb(3+)-doped region for the high-order mode content to be carefully controlled. A ratio of the Yb(3+)-doped region diameter to the overall core diameter of 40% allows for single-mode emission, even for small spool diameters of 15 cm. Such a fiber was manufactured and subsequently used as the core element of a cw oscillator. Very good beam quality parameter M(2)=1.12 and slope efficiency of 80% were measured. Insensitivity to bending, exemplified by the absence of temporal drift of the beam, was demonstrated for curvature diameter as small as 15 cm.

  15. Effects of abutment diameter, luting agent type, and re-cementation on the retention of implant-supported CAD/CAM metal copings over short abutments.

    PubMed

    Safari, Sina; Hosseini Ghavam, Fereshteh; Amini, Parviz; Yaghmaei, Kaveh

    2018-02-01

    The aim of this study was to evaluate the effects of abutment diameter, cement type, and re-cementation on the retention of implant-supported CAD/CAM metal copings over short abutments. Sixty abutments with two different diameters, the height of which was reduced to 3 mm, were vertically mounted in acrylic resin blocks with matching implant analogues. The specimens were divided into 2 diameter groups: 4.5 mm and 5.5 mm (n=30). For each abutment a CAD/CAM metal coping was manufactured, with an occlusal loop. Each group was sub-divided into 3 sub-groups (n=10). In each subgroup, a different cement type was used: resin-modified glass-ionomer, resin cement and zinc-oxide-eugenol. After incubation and thermocycling, the removal force was measured using a universal testing machine at a cross-head speed of 0.5 mm/min. In zinc-oxide-eugenol group, after removal of the coping, the cement remnants were completely cleaned and the copings were re-cemented with resin cement and re-tested. Two-way ANOVA, post hoc Tukey tests, and paired t-test were used to analyze data (α=.05). The highest pulling force was registered in the resin cement group (414.8 N), followed by the re-cementation group (380.5 N). Increasing the diameter improved the retention significantly ( P =.006). The difference in retention between the cemented and recemented copings was not statistically significant ( P =.40). Resin cement provided retention almost twice as strong as that of the RMGI. Increasing the abutment diameter improved retention significantly. Re-cementation with resin cement did not exhibit any difference from the initial cementation with resin cement.

  16. Normative biometry of the fetal brain using magnetic resonance imaging.

    PubMed

    Kyriakopoulou, Vanessa; Vatansever, Deniz; Davidson, Alice; Patkee, Prachi; Elkommos, Samia; Chew, Andrew; Martinez-Biarge, Miriam; Hagberg, Bibbi; Damodaram, Mellisa; Allsop, Joanna; Fox, Matt; Hajnal, Joseph V; Rutherford, Mary A

    2017-07-01

    The fetal brain shows accelerated growth in the latter half of gestation, and these changes can be captured by 2D and 3D biometry measurements. The aim of this study was to quantify brain growth in normal fetuses using Magnetic Resonance Imaging (MRI) and to produce reference biometry data and a freely available centile calculator ( https://www.developingbrain.co.uk/fetalcentiles/ ). A total of 127 MRI examinations (1.5 T) of fetuses with a normal brain appearance (21-38 gestational weeks) were included in this study. 2D and 3D biometric parameters were measured from slice-to-volume reconstructed images, including 3D measurements of supratentorial brain tissue, lateral ventricles, cortex, cerebellum and extra-cerebral CSF and 2D measurements of brain biparietal diameter and fronto-occipital length, skull biparietal diameter and occipitofrontal diameter, head circumference, transverse cerebellar diameter, extra-cerebral CSF, ventricular atrial diameter, and vermis height, width, and area. Centiles were constructed for each measurement. All participants were invited for developmental follow-up. All 2D and 3D measurements, except for atrial diameter, showed a significant positive correlation with gestational age. There was a sex effect on left and total lateral ventricular volumes and the degree of ventricular asymmetry. The 5th, 50th, and 95th centiles and a centile calculator were produced. Developmental follow-up was available for 73.1% of cases [mean chronological age 27.4 (±10.2) months]. We present normative reference charts for fetal brain MRI biometry at 21-38 gestational weeks. Developing growth trajectories will aid in the better understanding of normal fetal brain growth and subsequently of deviations from typical development in high-risk pregnancies or following premature delivery.

  17. Effects of abutment diameter, luting agent type, and re-cementation on the retention of implant-supported CAD/CAM metal copings over short abutments

    PubMed Central

    Safari, Sina; Amini, Parviz; Yaghmaei, Kaveh

    2018-01-01

    PURPOSE The aim of this study was to evaluate the effects of abutment diameter, cement type, and re-cementation on the retention of implant-supported CAD/CAM metal copings over short abutments. MATERIALS AND METHODS Sixty abutments with two different diameters, the height of which was reduced to 3 mm, were vertically mounted in acrylic resin blocks with matching implant analogues. The specimens were divided into 2 diameter groups: 4.5 mm and 5.5 mm (n=30). For each abutment a CAD/CAM metal coping was manufactured, with an occlusal loop. Each group was sub-divided into 3 sub-groups (n=10). In each subgroup, a different cement type was used: resin-modified glass-ionomer, resin cement and zinc-oxide-eugenol. After incubation and thermocycling, the removal force was measured using a universal testing machine at a cross-head speed of 0.5 mm/min. In zinc-oxide-eugenol group, after removal of the coping, the cement remnants were completely cleaned and the copings were re-cemented with resin cement and re-tested. Two-way ANOVA, post hoc Tukey tests, and paired t-test were used to analyze data (α=.05). RESULTS The highest pulling force was registered in the resin cement group (414.8 N), followed by the re-cementation group (380.5 N). Increasing the diameter improved the retention significantly (P=.006). The difference in retention between the cemented and recemented copings was not statistically significant (P=.40). CONCLUSION Resin cement provided retention almost twice as strong as that of the RMGI. Increasing the abutment diameter improved retention significantly. Re-cementation with resin cement did not exhibit any difference from the initial cementation with resin cement. PMID:29503708

  18. Lightweight piston-rod assembly for a reciprocating machine

    DOEpatents

    Corey, John A.; Walsh, Michael M.

    1986-01-01

    In a reciprocating machine, there is provided a hollow piston including a dome portion on one end and a base portion on the opposite end. The base portion includes a central bore into which a rod is hermetically fixed in radial and angular alignment. The extending end of the rod has a reduced diameter portion adapted to fit into the central bore of a second member such as a cross-head assembly, and to be secured thereto in radial and axial alignment with the piston.

  19. ANOMALOUS HEAD POSTURES IN STRABISMUS AND NYSTAGMUS - DIAGNOSIS AND MANAGEMENT -

    PubMed Central

    Teodorescu, Luminita

    2015-01-01

    Abnormal head positions are adopted in order to improve visual acuity, to avoid diplopia or to obtain a more comfortable binocular vision. The head can be turned or tilted toward right or left, with the chin rotated up or downwards or combination of these positions. The ophthalmologic examination including the assessment of versions leads to the diagnosis. When versions are free, the cause may be congenital nystagmus or strabismus with large angle. When versions are limited we suspect paralytic or restrictive strabismus. The head tilted to one shoulder suggests cyclotropia (IV Nerve Palsy) or congenital nystagmus. We present few of the above cases. An adequate surgical treatment can improve or correct the ocular deviation, diplopia and the abnormal head posture. Conclusions: The abnormal head posture must be assessed and treated early in order to correct the ocular position and head posture. All patient presenting abnormal head position HAD TO BE investigated by an ophthalmologist. PMID:26978880

  20. Topographical distribution and morphology of NADPH-diaphorase-stained neurons in the human claustrum

    PubMed Central

    Hinova-Palova, Dimka V.; Edelstein, Lawrence; Landzhov, Boycho; Minkov, Minko; Malinova, Lina; Hristov, Stanislav; Denaro, Frank J.; Alexandrov, Alexandar; Kiriakova, Teodora; Brainova, Ilina; Paloff, Adrian; Ovtscharoff, Wladimir

    2014-01-01

    We studied the topographical distribution and morphological characteristics of NADPH-diaphorase-positive neurons and fibers in the human claustrum. These neurons were seen to be heterogeneously distributed throughout the claustrum. Taking into account the size and shape of stained perikarya as well as dendritic and axonal characteristics, Nicotinamide adenine dinucleotide phosphate-diaphorase (NADPHd)-positive neurons were categorized by diameter into three types: large, medium and small. Large neurons ranged from 25 to 35 μm in diameter and typically displayed elliptical or multipolar cell bodies. Medium neurons ranged from 20 to 25 μm in diameter and displayed multipolar, bipolar and irregular cell bodies. Small neurons ranged from 14 to 20 μm in diameter and most often displayed oval or elliptical cell bodies. Based on dendritic characteristics, these neurons were divided into spiny and aspiny subtypes. Our findings reveal two populations of NADPHd-positive neurons in the human claustrum—one comprised of large and medium cells consistent with a projection neuron phenotype, the other represented by small cells resembling the interneuron phenotype as defined by previous Golgi impregnation studies. PMID:24904317

  1. Staged curative treatment of a complex direct carotid-cavernous fistula with a large arterial defect and an 'oversized' internal carotid artery.

    PubMed

    Bender, Matthew T; Lin, Li-Mei; Coon, Alexander L; Colby, Geoffrey P

    2017-06-14

    This is a case of a high-flow, post-traumatic direct carotid-cavernous fistula with a widened arterial defect and a large-diameter internal carotid artery (ICA). The unique aspect of this case is the oversized ICA, >8mm in diameter, which is both a pathological and a therapeutic challenge, given the lack of available neuroendovascular devices for full vessel reconstruction. We present a planned two-stage embolisation paradigm for definitive treatment. Transarterial coil embolisation is performed as the first stage to disconnect the fistula and normalise flow in the ICA. A 3-month recovery period is then allowed for reduction in carotid diameter. Repair of the large vessel defect and pseudoaneurysm is performed as a second stage in a delayed fashion with a flow-diverting device. Follow-up angiography at 6 months demonstrates obliteration of the fistula and curative ICA reconstruction to a diameter <5mm. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  2. A prospective study of fetal head growth, autistic traits and autism spectrum disorder.

    PubMed

    Blanken, Laura M E; Dass, Alena; Alvares, Gail; van der Ende, Jan; Schoemaker, Nikita K; El Marroun, Hanan; Hickey, Martha; Pennell, Craig; White, Scott; Maybery, Murray T; Dissanayake, Cheryl; Jaddoe, Vincent W V; Verhulst, Frank C; Tiemeier, Henning; McIntosh, Will; White, Tonya; Whitehouse, Andrew

    2018-04-01

    Altered trajectories of brain growth are often reported in Autism Spectrum Disorder (ASD), particularly during the first year of life. However, less is known about prenatal head growth trajectories, and no study has examined the relation with postnatal autistic symptom severity. The current study prospectively examined the association between fetal head growth and the spectrum of autistic symptom severity in two large population-based cohorts, including a sample of individuals with clinically diagnosed ASD. This study included 3,820 children from two longitudinal prenatal cohorts in The Netherlands and Australia, comprising 60 individuals with a confirmed diagnosis of ASD. Latent growth curve models were used to examine the relationship between fetal head circumference measured at three different time points and autistic traits measured in postnatal life using either the Social Responsiveness Scale or the Autism-Spectrum Quotient. While lower initial prenatal HC was weakly associated with increasing autistic traits in the Dutch cohort, this relationship was not observed in the Australian cohort, nor when the two cohorts were analysed together. No differences in prenatal head growth were found between individuals with ASD and controls. This large population-based study identified no consistent association across two cohorts between prenatal head growth and postnatal autistic traits. Our mixed findings suggest that further research in this area is needed. Autism Res 2018, 11: 602-612. © 2018 The Authors Autism Research published by International Society for Autism Research and Wiley Periodicals, Inc. It is not known whether different patterns of postnatal brain growth in Autism Spectrum Disorder (ASD) also occurs prenatally. We examined fetal head growth and autistic symptoms in two large groups from The Netherlands and Australia. Lower initial prenatal head circumference was associated with autistic traits in the Dutch, but not the Australian, group. No differences in head growth were found in individuals with ASD and controls when the data was combined. Our mixed findings suggest that more research in this area is needed. © 2018 The Authors Autism Research published by International Society for Autism Research and Wiley Periodicals, Inc.

  3. Multi-Head Very High Power Strobe System For Motion Picture Special Effects

    NASA Astrophysics Data System (ADS)

    Lovoi, P. A.; Fink, Michael L.

    1983-10-01

    A very large camera synchronizable strobe system has been developed for motion picture special effects. This system, the largest ever built, was delivered to MGM/UA to be used in the movie "War Games". The system consists of 12 individual strobe heads and a power supply distribution system. Each strobe head operates independently and may be flashed up to 24 times per second under computer control. An energy of 480 Joules per flash is used in six strobe heads and 240 Joules per flash in the remaining six strobe heads. The beam pattern is rectangular with a FWHM of 60° x 48°.

  4. US Intergroup Anal Carcinoma Trial: Tumor Diameter Predicts for Colostomy

    PubMed Central

    Ajani, Jaffer A.; Winter, Kathryn A.; Gunderson, Leonard L.; Pedersen, John; Benson, Al B.; Thomas, Charles R.; Mayer, Robert J.; Haddock, Michael G.; Rich, Tyvin A.; Willett, Christopher G.

    2009-01-01

    Purpose The US Gastrointestinal Intergroup Radiation Therapy Oncology Group 98-11 anal carcinoma trial showed that cisplatin-based concurrent chemoradiotherapy resulted in a significantly higher rate of colostomy compared with mitomycin-based therapy. Established prognostic variables for patients with anal carcinoma include tumor diameter, clinical nodal status, and sex, but pretreatment variables that would predict the likelihood of colostomy are unknown. Methods A secondary analysis was performed by combining patients in the two treatment arms to evaluate whether new predictive and prognostic variables would emerge. Univariate and multivariate analyses were carried out to correlate overall survival (OS), disease-free survival, and time to colostomy (TTC) with pretreatment and treatment variables. Results Of 682 patients enrolled, 644 patients were assessable and analyzed. In the multivariate analysis, tumor-related prognosticators for poorer OS included node-positive cancer (P ≤ .0001), large (> 5 cm) tumor diameter (P = .01), and male sex (P = .016). In the treatment-related categories, cisplatin-based therapy was statistically significantly associated with a higher rate of colostomy (P = .03) than was mitomycin-based therapy. In the pretreatment variables category, only large tumor diameter independently predicted for TTC (P = .008). Similarly, the cumulative 5-year colostomy rate was statistically significantly higher for large tumor diameter than for small tumor diameter (Gray's test; P = .0074). Clinical nodal status and sex were not predictive of TTC. Conclusion The combined analysis of the two arms of RTOG 98-11, representing the largest prospective database, reveals that tumor diameter (irrespective of the nodal status) is the only independent pretreatment variable that predicts TTC and 5-year colostomy rate in patients with anal carcinoma. PMID:19139424

  5. On the weight-bearing function of the medial coronoid process in dogs.

    PubMed

    Breit, S; Künzel, W; Seiler, S

    2006-02-01

    The shape of and proportions between the surface areas of the medial coronoid process (MCP) and the fovea of the radial head were determined in 88 juvenile dogs and 146 adult dogs grouped as giant, large, mid-sized, chondrodystrophic, or small dogs. Thereby, the longitudinal (length) and transverse (width) extension of the MCP and fovea of the radial head have been measured. Original values were used to describe changes of the parameters attributed to growth. Normalized values (i.e. values expected in case of a width of the fovea of the radial head of 20 mm) were used to determine potential differences between constitutional types. All original values increased during growth (P < 0.05) except for the width and length of the MCP in chondrodystrophic and small breeds. Normalized values revealed a proportional decrease in width and length of the MCP during growth (P < 0.05) compared with the radial head. In adults, the normalized MCP was widest in giant dogs followed by large, mid-sized, small, and chondrodystrophic breeds. The MCP was also longest in giant dogs but shortest in large and chondrodystrophic dogs with those of large dogs being significantly (P < 0.05) shorter than those in giant, mid-sized and small dogs. Present results suggest that a deficiency in length-growth of the MCP--which has been present especially in large dogs--results in smaller humeral contact areas and decreased weight-bearing capacity of the MCP. Because loading forces acting on the MCP increase with body weight, the condition noted in large dogs might increase the risk of fragmentation of the MCP in these.

  6. Modeling heading and path perception from optic flow in the case of independently moving objects

    PubMed Central

    Raudies, Florian; Neumann, Heiko

    2013-01-01

    Humans are usually accurate when estimating heading or path from optic flow, even in the presence of independently moving objects (IMOs) in an otherwise rigid scene. To invoke significant biases in perceived heading, IMOs have to be large and obscure the focus of expansion (FOE) in the image plane, which is the point of approach. For the estimation of path during curvilinear self-motion no significant biases were found in the presence of IMOs. What makes humans robust in their estimation of heading or path using optic flow? We derive analytical models of optic flow for linear and curvilinear self-motion using geometric scene models. Heading biases of a linear least squares method, which builds upon these analytical models, are large, larger than those reported for humans. This motivated us to study segmentation cues that are available from optic flow. We derive models of accretion/deletion, expansion/contraction, acceleration/deceleration, local spatial curvature, and local temporal curvature, to be used as cues to segment an IMO from the background. Integrating these segmentation cues into our method of estimating heading or path now explains human psychophysical data and extends, as well as unifies, previous investigations. Our analysis suggests that various cues available from optic flow help to segment IMOs and, thus, make humans' heading and path perception robust in the presence of such IMOs. PMID:23554589

  7. Structural and electronic properties of rectangular CdTe nanowire: A DST study

    NASA Astrophysics Data System (ADS)

    Khan, Md. Shahzad; Bhatia, Manjeet; Srivastava, Anurag

    2018-05-01

    CdTe rectangular nanowire of different diameter in zinc-blende phase is investigated using density functional theory. Enhancement of diameter increased stability and improved electronic qualities suitable for device purpose applications. Cohesive energy per atom enhanced on enlarging diameter advocating the stability. Large diameter nanowire (22.62Å) exhibits bandgap of 1.21eV and electronic effective mass is observed to be 0.51me. The bonding between Cd-Te atoms are predominantly observed as covalent assuring its inertness towards moisture.

  8. Clustering, randomness, and regularity in cloud fields: 2. Cumulus cloud fields

    NASA Astrophysics Data System (ADS)

    Zhu, T.; Lee, J.; Weger, R. C.; Welch, R. M.

    1992-12-01

    During the last decade a major controversy has been brewing concerning the proper characterization of cumulus convection. The prevailing view has been that cumulus clouds form in clusters, in which cloud spacing is closer than that found for the overall cloud field and which maintains its identity over many cloud lifetimes. This "mutual protection hypothesis" of Randall and Huffman (1980) has been challenged by the "inhibition hypothesis" of Ramirez et al. (1990) which strongly suggests that the spatial distribution of cumuli must tend toward a regular distribution. A dilemma has resulted because observations have been reported to support both hypotheses. The present work reports a detailed analysis of cumulus cloud field spatial distributions based upon Landsat, Advanced Very High Resolution Radiometer, and Skylab data. Both nearest-neighbor and point-to-cloud cumulative distribution function statistics are investigated. The results show unequivocally that when both large and small clouds are included in the cloud field distribution, the cloud field always has a strong clustering signal. The strength of clustering is largest at cloud diameters of about 200-300 m, diminishing with increasing cloud diameter. In many cases, clusters of small clouds are found which are not closely associated with large clouds. As the small clouds are eliminated from consideration, the cloud field typically tends towards regularity. Thus it would appear that the "inhibition hypothesis" of Ramirez and Bras (1990) has been verified for the large clouds. However, these results are based upon the analysis of point processes. A more exact analysis also is made which takes into account the cloud size distributions. Since distinct clouds are by definition nonoverlapping, cloud size effects place a restriction upon the possible locations of clouds in the cloud field. The net effect of this analysis is that the large clouds appear to be randomly distributed, with only weak tendencies towards regularity. For clouds less than 1 km in diameter, the average nearest-neighbor distance is equal to 3-7 cloud diameters. For larger clouds, the ratio of cloud nearest-neighbor distance to cloud diameter increases sharply with increasing cloud diameter. This demonstrates that large clouds inhibit the growth of other large clouds in their vicinity. Nevertheless, this leads to random distributions of large clouds, not regularity.

  9. Development of SiC Large Tapered Crystal Growth

    NASA Technical Reports Server (NTRS)

    Neudeck, Phil

    2011-01-01

    Research Focus Area: Power Electronics, Temperature Tolerant Devices. Demonstrate initial feasibility of totally new "Large Tapered Crystal" (LTC) process for growing vastly improved large-diameter wide-band gap wafers. Addresses Targets: The goal of this research is to experimentally investigate and demonstrate feasibility of the key unproven LTC growth processes in SiC. Laser-assisted growth of long SiC fiber seeds. Radial epitaxial growth enlargement of seeds into large SiC boules. Uniqueness and Impacts open a new technology path to large-diameter SiC and GaN wafers with 1000-fold defect density improvement at 2-4 fold lower cost. Leapfrog improvement in wide band gap power device capability and cost.

  10. Economic feasibility of products from inland West small-diameter timber

    Treesearch

    Spelter Henry; Rong Wang; Peter Ince

    1996-01-01

    A large part of the forests located in the Rocky Mountain region of the U.S. West (inland West) is characterized by densely packed, small-diameter stands. The purpose of this study was to examine the economic feasibility of using small-diameter material from this resource to manufacture various wood products: oriented strandboard (OSB), stud lumber, random-length...

  11. Raise cutting diameters for increased returns

    Treesearch

    H. Clay Smith; G. R., Jr. Trimble; Paul S. DeBald

    1979-01-01

    Diameter-limit cutting is widely used to harvest logs in eastern hardwoods. Studies show that cutting limits are often set so low that they sacrifice financial returns. The value of lumber cut from logs is largely dependent on the diameter, grade, and tree species. As tree size increases so does the proportion of higher grade lumber, and this is reflected in improved...

  12. Comparison of Fixed Diameter-Limit and Selection Cutting in Northern Conifers

    Treesearch

    Laura S. Kenefic; Paul E. Sendak; John C. Brissette

    2005-01-01

    Diameter-limit cutting is a common type of harvest in which all merchantable trees above specific size thresholds are removed. Despite a long history of application, controlled experiments of these harvests are rare and the cumulative effects of repeated diameter-limit cuts are largely unknown. The Penobscot Experimental Forest in Maine is the location of a long-term...

  13. Megalencephalic Leukoencephalopathy with Subcortical Cysts (MLC)

    MedlinePlus

    ... patients, the first symptom is an increase in head circumference in the first year of life. Patients can have a delayed development and may subsequently show neurological deterioration ... an abnormally large head Seizures (present in ~75% of patients and most ...

  14. Is extreme bite performance associated with extreme morphologies in sharks?

    PubMed

    Huber, Daniel R; Claes, Julien M; Mallefet, Jérôme; Herrel, Anthony

    2009-01-01

    As top predators in many oceanic communities, sharks are known to eat large prey and are supposedly able to generate high bite forces. This notion has, however, largely gone untested due to the experimental intractability of these animals. For those species that have been investigated, it remains unclear whether their high bite forces are simply a consequence of their large body size or the result of diet-related adaptation. As aquatic poikilotherms, sharks can grow very large, making them ideal subjects with which to investigate the effects of body size on bite force. Relative bite-force capacity is often associated with changes in head shape because taller or wider heads can, for example, accommodate larger jaw muscles. Constraints on bite force in general may also be released by changes in tooth shape. For example, more pointed teeth may allow a predator to penetrate prey more effectively than blunt, pavementlike teeth. Our analyses show that large sharks do not bite hard for their body size, but they generally have larger heads. Head width is the best predictor of bite force across the species included in our study as indicated by a multiple regression model. Contrary to our predictions, sharks with relatively high bite forces for their body size also have relatively more pointed teeth at the front of the tooth row. Moreover, species including hard prey in their diet are characterized by high bite forces and narrow and pointed teeth at the jaw symphysis.

  15. Effect of alternate day collection on semen quality of Asian elephants (Elephas maximus) with poor initial fresh semen quality.

    PubMed

    Imrat, P; Mahasawangkul, S; Thitaram, C; Suthanmapinanth, P; Kornkaewrat, K; Sombutputorn, P; Jansittiwate, S; Thongtip, N; Pinyopummin, A; Colenbrander, B; Holt, W V; Stout, T A E

    2014-06-30

    In captivity, male Asian elephants often yield poor quality semen after transrectal manually assisted semen collection; however, the reasons for the disappointing semen quality are not clear. Here we test the hypothesis that accumulation of senescent spermatozoa is a contributory factor, and that semen quality can therefore be improved by more frequent ejaculation. To this end we investigated the effect of collecting semen five times on alternate days, after a long period of sexual rest, on semen quality in Asian elephants known to deliver poor semen during infrequent single collections. All eight bulls initially displayed a high incidence of detached sperm heads and low percentages of motile (close to 0%) spermatozoa. After semen collection on alternate days, the percentages of detached sperm heads, and head and mid-piece abnormalities, were reduced significantly (p<0.05). In particular, one bull showed markedly improved sperm motility (increased from 0% to 60%) and membrane integrity (increased from 5% to 75%). In addition, advancing age significantly (p<0.01) correlated with lower percentages of sperm with intact membranes and a higher frequency of detached sperm heads. In contrast to sperm accumulation problems in other species, a small ampullary diameter correlated significantly (p<0.05) with reduced semen quality. Copyright © 2014 Elsevier B.V. All rights reserved.

  16. Sclerotherapy of voluminous venous malformation in head and neck with absolute ethanol under digital subtraction angiography guidance.

    PubMed

    Wang, Y A; Zheng, J W; Zhu, H G; Ye, W M; He, Y; Zhang, Z Y

    2010-06-01

    Venous malformation (VM) is the most common symptomatic low-flow vascular malformation, which predominantly occurs in the head and neck region. The aim of this paper was to evaluate the results of endovascular sclerotherapy of voluminous VM, when the lesion is either >or=15 cm in maximum diameter or the lesion invades more than one anatomical space, in the head and neck region using absolute ethanol under digital subtraction angiography (DSA) guidance. A total of 23 patients with head and neck VMs between October 2005 and December 2008 were retrospectively reviewed. All patients received direct puncture ethanol sclerotherapy under DSA guidance. Follow-up assessments were performed at 3-25 months after therapies were completed, and complications were reported in some cases. All patients were satisfied with the results of therapy. Seventeen patients (73.9%) achieved excellent responses and six patients (26.1%) achieved good responses in magnetic resonance imaging assessments. Minor complications developed during the procedures, all of which were successfully managed with full recovery during follow-ups. Serious complications such as acute pulmonary hypertension, cardiovascular collapse and pulmonary embolism were not encountered. It is concluded that sclerotherapy with absolute ethanol under DSA guidance is an important alternative therapy for voluminous and extensive VM, as the procedure is reasonably safe and offers good therapeutic results.

  17. Space transportation booster engine thrust chamber technology, large scale injector

    NASA Technical Reports Server (NTRS)

    Schneider, J. A.

    1993-01-01

    The objective of the Large Scale Injector (LSI) program was to deliver a 21 inch diameter, 600,000 lbf thrust class injector to NASA/MSFC for hot fire testing. The hot fire test program would demonstrate the feasibility and integrity of the full scale injector, including combustion stability, chamber wall compatibility (thermal management), and injector performance. The 21 inch diameter injector was delivered in September of 1991.

  18. Morphological alterations of T24 cells on flat and nanotubular TiO2 surfaces.

    PubMed

    Imani, Roghayeh; Kabaso, Doron; Erdani Kreft, Mateja; Gongadze, Ekaterina; Penic, Samo; Elersic, Kristina; Kos, Andrej; Veranic, Peter; Zorec, Robert; Iglic, Ales

    2012-12-01

    To investigate morphological alterations of malignant cancer cells (T24) of urothelial origin seeded on flat titanium (Ti) and nanotubular TiO(2) (titanium dioxide) nanostructures. Using anodization method, TiO(2) surfaces composed of vertically aligned nanotubes of 50-100 nm diameters were produced. The flat Ti surface was used as a reference. The alteration in the morphology of cancer cells was evaluated using scanning electron microscopy (SEM). A computational model, based on the theory of membrane elasticity, was constructed to shed light on the biophysical mechanisms responsible for the observed changes in the contact area of adhesion. Large diameter TiO(2) nanotubes exhibited a significantly smaller contact area of adhesion (P<0.0001) and had more membrane protrusions (eg, microvilli and intercellular membrane nanotubes) than on flat Ti surface. Numerical membrane dynamics simulations revealed that the low adhesion energy per unit area would hinder the cell spreading on the large diameter TiO(2) nanotubular surface, thus explaining the small contact area. The reduction in the cell contact area in the case of large diameter TiO(2) nanotube surface, which does not enable formation of the large enough number of the focal adhesion points, prevents spreading of urothelial cells.

  19. Analysis of linear head accelerations from collegiate football impacts.

    PubMed

    Brolinson, P Gunnar; Manoogian, Sarah; McNeely, David; Goforth, Mike; Greenwald, Richard; Duma, Stefan

    2006-02-01

    Sports-related concussions result in 300,000 brain injuries in the United States each year. We conducted a study utilizing an in-helmet system that measures and records linear head accelerations to analyze head impacts in collegiate football. The Head Impact Telemetry (HIT) System is an in-helmet system with six spring-mounted accelerometers and an antenna that transmits data via radio frequency to a sideline receiver and laptop computer system. A total of 11,604 head impacts were recorded from the Virginia Tech football team throughout the 2003 and 2004 football seasons during 22 games and 62 practices from a total of 52 players. Although the incidence of injury data are limited, this study presents an extremely large data set from human head impacts that provides valuable insight into the lower limits of head acceleration that cause mild traumatic brain injuries.

  20. The influence of maximum running speed on eye size: a test of Leuckart's Law in mammals.

    PubMed

    Heard-Booth, Amber N; Kirk, E Christopher

    2012-06-01

    Vertebrate eye size is influenced by many factors, including body or head size, diet, and activity pattern. Locomotor speed has also been suggested to influence eye size in a relationship known as Leuckart's Law. Leuckart's Law proposes that animals capable of achieving fast locomotor speeds require large eyes to enhance visual acuity and avoid collisions with environmental obstacles. The selective influence of rapid flight has been invoked to explain the relatively large eyes of birds, but Leuckart's Law remains untested in nonavian vertebrates. This study investigates the relationship between eye size and maximum running speed in a diverse sample of mammals. Measures of axial eye diameter, maximum running speed, and body mass were collected from the published literature for 50 species from 10 mammalian orders. This analysis reveals that absolute eye size is significantly positively correlated with maximum running speed in mammals. Moreover, the relationship between eye size and running speed remains significant when the potentially confounding effects of body mass and phylogeny are statistically controlled. The results of this analysis are therefore consistent with the expectations of Leuckart's Law and demonstrate that faster-moving mammals have larger eyes than their slower-moving close relatives. Accordingly, we conclude that maximum running speed is one of several key selective factors that have influenced the evolution of eye size in mammals. Copyright © 2012 Wiley Periodicals, Inc.

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