Spine device clinical trials: design and sponsorship.
Cher, Daniel J; Capobianco, Robyn A
2015-05-01
Multicenter prospective randomized clinical trials represent the best evidence to support the safety and effectiveness of medical devices. Industry sponsorship of multicenter clinical trials is purported to lead to bias. To determine what proportion of spine device-related trials are industry-sponsored and the effect of industry sponsorship on trial design. Analysis of data from a publicly available clinical trials database. Clinical trials of spine devices registered on ClinicalTrials.gov, a publicly accessible trial database, were evaluated in terms of design, number and location of study centers, and sample size. The relationship between trial design characteristics and study sponsorship was evaluated using logistic regression and general linear models. One thousand six hundred thrity-eight studies were retrieved from ClinicalTrials.gov using the search term "spine." Of the 367 trials that focused on spine surgery, 200 (54.5%) specifically studied devices for spine surgery and 167 (45.5%) focused on other issues related to spine surgery. Compared with nondevice trials, device trials were far more likely to be sponsored by the industry (74% vs. 22.2%, odds ratio (OR) 9.9 [95% confidence interval 6.1-16.3]). Industry-sponsored device trials were more likely multicenter (80% vs. 29%, OR 9.8 [4.8-21.1]) and had approximately four times as many participating study centers (p<.0001) and larger sample sizes. There were very few US-based multicenter randomized trials of spine devices not sponsored by the industry. Most device-related spine research is industry-sponsored. Multicenter trials are more likely to be industry-sponsored. These findings suggest that previously published studies showing larger effect sizes in industry-sponsored vs. nonindustry-sponsored studies may be biased as a result of failure to take into account the marked differences in design and purpose. Copyright © 2015 Elsevier Inc. All rights reserved.
Industry sponsorship and research outcome.
Lundh, Andreas; Sismondo, Sergio; Lexchin, Joel; Busuioc, Octavian A; Bero, Lisa
2012-12-12
Clinical research affecting how doctors practice medicine is increasingly sponsored by companies that make drugs and medical devices. Previous systematic reviews have found that pharmaceutical industry sponsored studies are more often favorable to the sponsor's product compared with studies with other sources of sponsorship. This review is an update using more stringent methodology and also investigating sponsorship of device studies. To investigate whether industry sponsored drug and device studies have more favorable outcomes and differ in risk of bias, compared with studies having other sources of sponsorship. We searched MEDLINE (1948 to September 2010), EMBASE (1980 to September 2010), the Cochrane Methodology Register (Issue 4, 2010) and Web of Science (August 2011). In addition, we searched reference lists of included papers, previous systematic reviews and author files. Cross-sectional studies, cohort studies, systematic reviews and meta-analyses that quantitatively compared primary research studies of drugs or medical devices sponsored by industry with studies with other sources of sponsorship. We had no language restrictions. Two assessors identified potentially relevant papers, and a decision about final inclusion was made by all authors. Two assessors extracted data, and we contacted authors of included papers for additional unpublished data. Outcomes included favorable results, favorable conclusions, effect size, risk of bias and whether the conclusions agreed with the study results. Two assessors assessed risk of bias of included papers. We calculated pooled risk ratios (RR) for dichotomous data (with 95% confidence intervals). Forty-eight papers were included. Industry sponsored studies more often had favorable efficacy results, risk ratio (RR): 1.24 (95% confidence interval (CI): 1.14 to 1.35), harms results RR: 1.87 (95% CI: 1.54 to 2.27) and conclusions RR: 1.31 (95% CI: 1.20 to 1.44) compared with non-industry sponsored studies. Ten papers reported on sponsorship and effect size, but could not be pooled due to differences in their reporting of data. The results were heterogeneous; five papers found larger effect sizes in industry sponsored studies compared with non-industry sponsored studies and five papers did not find a difference in effect size. Only two papers (including 120 device studies) reported separate data for devices and we did not find a difference between drug and device studies on the association between sponsorship and conclusions (test for interaction, P = 0.23). Comparing industry and non-industry sponsored studies, we did not find a difference in risk of bias from sequence generation, allocation concealment and follow-up. However, industry sponsored studies more often had low risk of bias from blinding, RR: 1.32 (95% CI: 1.05 to 1.65), compared with non-industry sponsored studies. In industry sponsored studies, there was less agreement between the results and the conclusions than in non-industry sponsored studies, RR: 0.84 (95% CI: 0.70 to 1.01). Sponsorship of drug and device studies by the manufacturing company leads to more favorable results and conclusions than sponsorship by other sources. Our analyses suggest the existence of an industry bias that cannot be explained by standard 'Risk of bias' assessments.
Abraham, Jean Marie; Feldman, Roger
2010-01-01
This study provides new estimates of demand for employer-sponsored health insurance, using the 1997-2001 linked Household Component-Insurance Component of the Medical Expenditure Panel Survey (MEPS). Our focus is on households' decisions to take up coverage through a worker's employer. We found a significant inverse relationship between the out-of-pocket premium and the probability of taking up coverage, with the price effect considerably larger when we used instrumental variables methods to account for endogenous out-of-pocket premiums. Additionally, workers in families with more children eligible for Medicaid were less likely to take up coverage.
Building a Local Space Situational Awareness (SSA) Architecture Using Hosted Payloads
2013-09-01
HOSTED PAYLOADS 5. FUNDING NUMBERS 6. AUTHOR(S) Farakh B. Zaman 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Postgraduate School...Monterey, CA 93943–5000 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING /MONITORING AGENCY NAME(S) AND ADDRESS(ES) N/A 10. SPONSORING...attached to larger satellites that typically perform missions independently of the host spacecraft. Hosted payloads afford a unique method to provide
Barton, Sarah; Peckitt, Clare; Sclafani, Francesco; Cunningham, David; Chau, Ian
2015-12-01
Correct interpretation of subgroup analyses (SGA) is important as it influences selection of therapeutic interventions for patient subsets. The primary aim of our study was to compare reporting of SGA between industry and non-industry sponsored trials. We performed a systematic literature review and extracted data from journal articles (JA) and conference abstracts (CA) published over a decade reporting SGA results of phase III randomised controlled gastrointestinal (GI) oncology trials with patient participants of ≥150. In JA, SGA was reported in 100/145 (69%) trials: 41/54 industry sponsored (76%; 95% confidence interval [CI]: 63-86%) and 59/91 non-industry sponsored (65%; 95% CI: 55-74%) trials (p = 0.16). In CA, SGA was reported in 86/204 (42%) trials: 43/83 industry sponsored (52%; 95% CI: 41-62%) and 43/121 non-industry sponsored (36%; 95% CI: 28-44%) trials (p = 0.02). Number of SGA performed per trial was significantly larger for industry compared to non-industry sponsored trials in both JA (median 6 versus 2, p = 0.003) and CA (median 1 versus 0, p = 0.023). Claims of subgroup effect were made in 52% of trials in JA and 50% in CA, with significant test of interaction evident in only 25% of JA and 16% of CA, with no difference between industry and non-industry trials. Industry sponsored trials with a significant primary end-point reported more SGA (p < 0.001 JA; p = 0.046 CA). Industry sponsored trials reported more SGA. Claimed subgroup effects were often not accompanied by significant interaction test; thus circumspection should be adopted when using SGA to deviate from standard therapeutic decision-making in GI oncology. Copyright © 2015 Elsevier Ltd. All rights reserved.
ERIC Educational Resources Information Center
Krasnow, Jean H.
A teacher action research study, undertaken as part of the larger Schools Reaching Out (SRO) project, sponsored by the Institute for Responsive Education, is described in this report. The project is based on the concept of the urban school, family, and community partnership as a means to improve all children's academic achievement and social…
The financial implications of employer-sponsored health insurance.
Natvig, Deborah; Tolbert, Sam
2005-01-01
The purpose of this study was to analyze utilization and costs of employer-sponsored health insurance in select businesses in a rural community in South Carolina. The study was conducted under the auspices of the HR Roundtable of the local Chamber of Commerce, composed of human resources directors from the larger area businesses. Twenty one companies were invited to participate and eight submitted information that was sufficiently complete to analyze. The participating companies employed 6,265 people, of which 5,712 were insured. The data represents a total of 13,057 covered lives. Although the findings cannot be generalized to a broader population, the descriptive data was sufficient to generate a discussion about health care issues for this community and for the group to make preliminary recommendations for collaborative work that may affect the costs of health care coverage for this community.
Flacco, Maria Elena; Manzoli, Lamberto; Boccia, Stefania; Capasso, Lorenzo; Aleksovska, Katina; Rosso, Annalisa; Scaioli, Giacomo; De Vito, Corrado; Siliquini, Roberta; Villari, Paolo; Ioannidis, John P A
2015-07-01
To map the current status of head-to-head comparative randomized evidence and to assess whether funding may impact on trial design and results. From a 50% random sample of the randomized controlled trials (RCTs) published in journals indexed in PubMed during 2011, we selected the trials with ≥ 100 participants, evaluating the efficacy and safety of drugs, biologics, and medical devices through a head-to-head comparison. We analyzed 319 trials. Overall, 238,386 of the 289,718 randomized subjects (82.3%) were included in the 182 trials funded by companies. Of the 182 industry-sponsored trials, only 23 had two industry sponsors and only three involved truly antagonistic comparisons. Industry-sponsored trials were larger, more commonly registered, used more frequently noninferiority/equivalence designs, had higher citation impact, and were more likely to have "favorable" results (superiority or noninferiority/equivalence for the experimental treatment) than nonindustry-sponsored trials. Industry funding [odds ratio (OR) 2.8; 95% confidence interval (CI): 1.6, 4.7] and noninferiority/equivalence designs (OR 3.2; 95% CI: 1.5, 6.6), but not sample size, were strongly associated with "favorable" findings. Fifty-five of the 57 (96.5%) industry-funded noninferiority/equivalence trials got desirable "favorable" results. The literature of head-to-head RCTs is dominated by the industry. Industry-sponsored comparative assessments systematically yield favorable results for the sponsors, even more so when noninferiority designs are involved. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.
The Space Debris Crisis: Time for an International Treaty
2011-03-23
TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Lieutenant Colonel Gregory D. Hillebrand Department of...Military Strategy, Planning, and Operations 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING / MONITORING AGENCY NAME(S) AND...problem is much larger than this. NASA estimates that There are more than 20,000 pieces of debris larger than a softball orbiting the Earth. They
Code of Federal Regulations, 2014 CFR
2014-04-01
...) Sponsor. No. 054771 in § 510.600(c) of this chapter. (c) Conditions of use—(1) Amount—(i) Dogs and cats. For cats and small breeds of dogs: 25 mg. For larger dogs: 50 mg. Administer by deep intramuscular...
The Relationship Between Colocation and Reenlistment in the Navy. Volume 1
of a larger CNA project titled The Effects of Personnel Policy Changes on Budgets and Manpower Inventories sponsored by the Office of the Assistant Secretary of the Navy (Financial Management and Comptroller)(ASN(FM and C)).
Sood, Neeraj; Ghosh, Arkadipta; Escarce, José J
2009-01-01
Objective To estimate the effect of growth in health care costs that outpaces gross domestic product (GDP) growth (“excess” growth in health care costs) on employment, gross output, and value added to GDP of U.S. industries. Study Setting We analyzed data from 38 U.S. industries for the period 1987–2005. All data are publicly available from various government agencies. Study Design We estimated bivariate and multivariate regressions. To develop the regression models, we assumed that rapid growth in health care costs has a larger effect on economic performance for industries where large percentages of workers receive employer-sponsored health insurance (ESI). We used the estimated regression coefficients to simulate economic outcomes under alternative scenarios of health care cost inflation. Results Faster growth in health care costs had greater adverse effects on economic outcomes for industries with larger percentages of workers who had ESI. We found that a 10 percent increase in excess growth in health care costs would have resulted in 120,803 fewer jobs, US$28,022 million in lost gross output, and US$14,082 million in lost value added in 2005. These declines represent 0.17 to 0.18 percent of employment, gross output, and value added in 2005. Conclusion Excess growth in health care costs is adversely affecting the economic performance of U.S. industries. PMID:19500165
Employer-sponsored health insurance and the gender wage gap.
Cowan, Benjamin; Schwab, Benjamin
2016-01-01
During prime working years, women have higher expected healthcare expenses than men. However, employees' insurance rates are not gender-rated in the employer-sponsored health insurance (ESI) market. Thus, women may experience lower wages in equilibrium from employers who offer health insurance to their employees. We show that female employees suffer a larger wage gap relative to men when they hold ESI: our results suggest this accounts for roughly 10% of the overall gender wage gap. For a full-time worker, this pay gap due to ESI is on the order of the expected difference in healthcare expenses between women and men. Copyright © 2015 Elsevier B.V. All rights reserved.
The Ecclesiology of Catholic University Mission: Learning from John Henry Newman and Vatican II
ERIC Educational Resources Information Center
Muldoon, Timothy P.
2017-01-01
Catholic universities in the United States have developed complexity reflective of the larger development of modern universities and "multiversities." This complexity, together with the decline in the numbers of sponsoring religious orders and diocesan priests, presents new challenges for the sustaining of a theologically rooted,…
Divorce Workshops: An Opportunity for Preventive Education & Epidemiological Research.
ERIC Educational Resources Information Center
Kalafat, John; And Others
This paper describes the program and research related to the "Making It" series of 18 multi-media divorce workshops co-sponsored by a community mental health center (CMHC) and a chapter of Parents without Partners (PWP). An introductory section discusses the rationale for larger scale community intervention and epidemiological research. The…
Models of Intervention for Children in Difficult Circumstances in South Africa.
ERIC Educational Resources Information Center
Sewpaul, Vishanthie
2001-01-01
Examines intervention models addressing the welfare of abused and neglected children and those affected by HIV/AIDS in South Africa. Notes larger, government-sponsored interventions and innovative local programs working with at-risk children, including the National Strategy on Child Abuse and Neglect, the Gauteng Programme of Action for Children,…
Worldwide Report. Telecommunications Policy, Research, and Development.
1985-11-06
important conclusions of the second meeting of the Andean Satellite Telecommunications Commission in Caracas , Venezuela , at which Colombia was represented...including many of the larger exchanges in the government telephone system, died by the wayside. In Metro Manila, there were two giant telephone...telephone services. The telecom- munications de - cade The telecommunications decade for the Philippines has preceded the ESCAP sponsored
What Students Need to Know about World War l. Footnotes. Volume 13, Number 19
ERIC Educational Resources Information Center
Neiberg, Michael
2008-01-01
This essay is based on the author's presentation at the Wachman Center's July 26-27, 2008 history institute, co-sponsored and hosted by the Cantigny First Division Foundation of the McCormick Tribune Foundation. For Europeans, World War I remains the epochal event of the twentieth century. For Americans, the war falls between two much larger and…
NASA sponsored Light Emitting Diode (LED) development helps in cancer treatment
NASA Technical Reports Server (NTRS)
1997-01-01
What started out as an attempt to develop a light which would allow for the growth of plants in space led to a remarkable discovery: The Light Emitting Diode (LED). This device through extensive study and experimentation has developed into a tool used by surgeons in the fight against brain cancer in children. Pictured is a mock-up of brain surgery being performed. By encapsulating the end of the LED with a balloon, light is diffused over a larger area of the brain allowing the surgeon a better view. This is one of many programs that begin as research for the space program, and through extensive study end up benefitting all of mankind.
Arab Threat Perceptions and the Future of the U.S. Military Presence in the Middle East
2015-10-01
knowledge, and provides solutions to strategic Army issues affecting the national security community . The Peacekeeping and Stability Operations...analysts concern topics having strategic implications for the Army, the Department of Defense, and the larger national security community . In addition...update the national security community on the research of our analysts, recent and forthcoming publications, and upcoming confer- ences sponsored by
Sood, Neeraj; Ghosh, Arkadipta; Escarce, José J
2009-10-01
To estimate the effect of growth in health care costs that outpaces gross domestic product (GDP) growth ("excess" growth in health care costs) on employment, gross output, and value added to GDP of U.S. industries. We analyzed data from 38 U.S. industries for the period 1987-2005. All data are publicly available from various government agencies. We estimated bivariate and multivariate regressions. To develop the regression models, we assumed that rapid growth in health care costs has a larger effect on economic performance for industries where large percentages of workers receive employer-sponsored health insurance (ESI). We used the estimated regression coefficients to simulate economic outcomes under alternative scenarios of health care cost inflation. Faster growth in health care costs had greater adverse effects on economic outcomes for industries with larger percentages of workers who had ESI. We found that a 10 percent increase in excess growth in health care costs would have resulted in 120,803 fewer jobs, US$28,022 million in lost gross output, and US$14,082 million in lost value added in 2005. These declines represent 0.17 to 0.18 percent of employment, gross output, and value added in 2005. Excess growth in health care costs is adversely affecting the economic performance of U.S. industries.
Funding sources for continuing medical education: An observational study
Venkataraman, Ramesh; Ranganathan, Lakshmi; Ponnish, Arun S.; Abraham, Babu K.; Ramakrishnan, Nagarajan
2014-01-01
Aims: Medical accreditation bodies and licensing authorities are increasingly mandating continuing medical education (CME) credits for maintenance of licensure of healthcare providers. However, the costs involved in participating in these CME activities are often substantial and may be a major deterrent in obtaining these mandatory credits. It is assumed that healthcare providers often obtain sponsorship from their institutions or third party payers (i.e. pharmaceutical-industry) to attend these educational activities. Data currently does not exist exploring the funding sources for CME activities in India. In this study, we examine the relative proportion of CME activities sponsored by self, institution and the pharmaceutical-industry. We also wanted to explore the characteristics of courses that have a high proportion of self-sponsorship. Materials and Methods: This is a retrospective audit of the data during the year 2009 conducted at an autonomous clinical training academy. The details of the sponsor of each CME activity were collected from an existing database. Participants were subsequently categorized as sponsored by self, sponsored by institution or sponsored by pharmaceutical-industry. Results: In the year 2009, a total of 2235 participants attended 40 different CME activities at the training academy. Of the total participants, 881 (39.4%) were sponsored by self, 898 (40.2%) were sponsored by institution and 456 (20.3%) by pharmaceutical-industry. About 47.8% participants attended courses that carried an international accreditation. For the courses that offer international accreditation, 63.3% were sponsored by self, 34.9% were sponsored by institution and 1.6% were sponsored by pharmaceutical-industry. There were 126 participants (5.6%) who returned to the academy for another CME activity during the study period. Self-sponsored (SS) candidates were more likely to sponsor themselves again for subsequent CME activity compared with the other two groups (P < 0.001). Conclusions: In our study, majority of healthcare professionals attending CME activities were either self or institution sponsored. There was a greater inclination for self-sponsoring for activities with international accreditation. SS candidates were more likely to sponsor themselves again for subsequent CME activities. PMID:25136190
Team sponsors in community-based health leadership programs.
Patterson, Tracy Enright; Dinkin, Donna R; Champion, Heather
2017-05-02
Purpose The purpose of this article is to share the lessons learned about the role of team sponsors in action-learning teams as part of community-based health leadership development programs. Design/methodology/approach This case study uses program survey results from fellow participants, action learning coaches and team sponsors to understand the value of sponsors to the teams, the roles they most often filled and the challenges they faced as team sponsors. Findings The extent to which the sponsors were perceived as having contributed to the work of the action learning teams varied greatly from team to team. Most sponsors agreed that they were well informed about their role. The roles sponsors most frequently played were to provide the teams with input and support, serve as a liaison to the community and serve as a sounding board, motivator and cheerleader. The most common challenges or barriers team sponsors faced in this role were keeping engaged in the process, adjusting to the role and feeling disconnected from the program. Practical implications This work provides insights for program developers and community foundations who are interested in building the capacity for health leadership by linking community sponsors with emerging leaders engaged in an action learning experience. Originality/value This work begins to fill a gap in the literature. The role of team sponsors has been studied for single organization work teams but there is a void of understanding about the role of sponsors with multi-organizational teams working to improve health while also learning about leadership.
Institutional Pathology and the Death of Dan Markingson.
Elliott, Carl
2017-01-01
In the spring of 2015, 11 years after a mentally ill young man named Dan Markingson stabbed himself to death in an industry-sponsored drug study, officials at the University of Minnesota suspended recruitment of subjects into drug trials in its Department of Psychiatry. University officials agreed to act only after a scathing investigation by Minnesota Office of the Legislative Auditor found damning evidence of coerced recruitment, inadequate clinical care, superficial research oversight, a web of serious, disturbing conflicts of interest, and a pattern of misleading public statements by university officials aimed at deflecting scrutiny. In this article, I examine the larger institutional factors leading up to Markingson's suicide and prevented corrective action for so long.
Capacity and readiness for quality improvement among home and community-based service providers.
Abrahamson, Kathleen; Myers, Jaclyn; Arling, Greg; Davila, Heather; Mueller, Christine; Abery, Brian; Cai, Yun
2016-01-01
The objective of this study was to explore home and community-based service (HCBS) providers' perspectives of organizational readiness for quality improvement (QI). Data were obtained from a survey of participants (N = 56) in a state-sponsored HCBS QI initiative. Quality improvement challenges included lack of time and resources, staff apprehension or resistance, resistance from consumers and families, and project sustainability. Support from leadership was viewed as an important factor in participating organizations' decision to engage in QI. Internal resources available to support QI varied widely between participating organizations, with differences observed between smaller and larger agencies, as well as between provider types and populations served.
Reflective baffle for BepiColombo mission
NASA Astrophysics Data System (ADS)
Rugi-Grond, E.; Weigel, T.; Herren, A.; Dominguez Calvo, M.; Krähenbühl, U.; Mouricaud, D.; Vayssade, H.
2017-11-01
The BepiColombo Spacecraft can't tolerate to absorb a major fraction of the off-axis sunlight through larger payload apertures. Fortunately, there are solutions to design baffles such that they reflect the incoming radiation back through the front aperture rather than absorbing it. A Design Study, sponsored by ESA and performed by Contraves Space together with SAGEM Défense Securité, has analysed the potential of various solutions and assessed the options to manufacture them. The selected configuration has been analysed in detail for the optical, mechanical and thermal performance as well as the impact on mass and power dissipation. The size of the baffle was adapted to the needs of the BepiColombo Laser Altimeter (BELA) payload.
Ethos and Vision Realization in Sponsored Academy Schools
ERIC Educational Resources Information Center
Gibson, Mark T.
2015-01-01
This article investigates the realization of ethos and vision in the early stages of sponsored academy schools in England. It is a qualitative nested case study of ten academies. Nineteen key actors were interviewed, including principals and sponsor representatives. The nests were organized by sponsor type. Key themes are discussed within the…
Bero, L; Anglemyer, A; Vesterinen, H; Krauth, D
2016-01-01
A critical component of systematic review methodology is the assessment of the risks of bias of studies that are included in the review. There is controversy about whether funding source should be included in a risk of bias assessment of animal toxicology studies. To determine whether industry research sponsorship is associated with methodological biases, the results, or conclusions of animal studies examining the effect of exposure to atrazine on reproductive or developmental outcomes. We searched multiple electronic databases and the reference lists of relevant articles to identify original research studies examining the effect of any dose of atrazine exposure at any life stage on reproduction or development in non-human animals. We compared methodological risks of bias, the conclusions of the studies, the statistical significance of the findings, and the magnitude of effect estimates between industry sponsored and non-industry sponsored studies. Fifty-one studies met the inclusion criteria. There were no differences in methodological risks of bias in industry versus non-industry sponsored studies. 39 studies tested environmentally relevant concentrations of atrazine (11 industry sponsored, 24 non-industry sponsored, 4 with no funding disclosures). Non-industry sponsored studies (12/24, 50.0%) were more likely to conclude that atrazine was harmful compared to industry sponsored studies (2/11, 18.1%) (p value=0.07). A higher proportion of non-industry sponsored studies reported statistically significant harmful effects (8/24, 33.3%) compared to industry-sponsored studies (1/11; 9.1%) (p value=0.13). The association of industry sponsorship with decreased effect sizes for harm outcomes was inconclusive. Our findings support the inclusion of research sponsorship as a risk of bias criterion in tools used to assess risks of bias in animal studies for systematic reviews. The reporting of other empirically based risk of bias criteria for animal studies, such as blinded outcome assessment, randomization, and all animals included in analyses, needs to improve to facilitate the assessment of studies for systematic reviews. Copyright © 2015 Elsevier Ltd. All rights reserved.
Mintzes, Barbara; Swandari, Swestika; Fabbri, Alice; Grundy, Quinn; Moynihan, Ray; Bero, Lisa
2018-02-13
To investigate patterns of industry-sponsored educational events that focus on specific health conditions for which there are concerns about overdiagnosis and overtreatment. This retrospective cohort study examines publicly reported industry-sponsored events in Australia from October 2011 to September 2015 for three conditions potentially subject to overdiagnosis and overtreatment: depression, osteoporosis and overactive bladder. We used a database of transparency reports to identify events with a focus on depression, osteoporosis and overactive bladder and compared these with other sponsored events. We hypothesised that companies marketing treatments for each condition would sponsor related events and that target audiences would mainly work in primary care, reflecting a broad patient population. Event and attendee characteristics, sponsoring companies, related marketed treatments, cost-effectiveness ratings and dispensing rates. Over the study period, we identified 1567 events focusing on depression, 1375 on osteoporosis and 190 on overactive bladder (total n=3132, with 96 660 attendees). These events were attended by primary care doctors more often than sponsored events without a focus on these three conditions: relative risk (RR)=3.06 (95% CI 2.81 to 3.32) for depression, RR=1.48 (95% CI 1.41 to 1.55) for osteoporosis and RR=2.59 (95% CI 2.09 to 3.21) for overactive bladder. Servier, which markets agomelatine and AstraZeneca (quetiapine) sponsored 51.2% and 23.0% of depression events, respectively. Amgen and GlaxoSmithKline, which co-market denosumab, sponsored 49.5% of osteoporosis events and Astellas and Commonwealth Serum Laboratories (CSL) (mirabegron and solifenacin) sponsored 80.5% of overactive bladder events. This 4-year overview of industry-sponsored events on three overdiagnosed and overtreated conditions found that primary care clinicians were often targeted, dinner was often provided and that a few companies sponsored most events. In most cases, sponsors' products are not cost-effective choices for the specified condition. This pattern highlights the need for professional education to be free of commercial sponsorship. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
ERIC Educational Resources Information Center
Bove, Liliana L.; Davies, W. Martin
2009-01-01
This case study outlines the use of client-sponsored research projects in a quantitative postgraduate marketing research subject conducted in a 12-week semester in a research-intensive Australian university. The case study attempts to address the dearth of recent literature on client-sponsored research projects in the discipline of marketing.…
1993-02-14
screening and significantly larger than that of majority electrons. plasmon-phonon coupling in the two-band hole sys - C! Later, Monte-Carlo simulations of...potential application to other laser sys - versus drive current for three cases; a nonlasing device tems as well. with no gain saturation, gain saturation...SAKU1, K,, HASEGAWA, T., FUSE, T., SMITA. T., ARITOME, S., WATA- were identically processed as the type A devices except for a NABE , $., 0HUCHI. K
2004-04-01
GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND...NUMBER 9. SPONSORING/MONITORING AGENCY NAME( S ) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM( S ) 11. SPONSOR/MONITOR’S REPORT NUMBER( S ) 12. DISTRIBUTION...Laboratories serve as S &T funding agencies, as research sponsors or as agents of research sponsors, it is hard to imagine any industrial or academic
Mintzes, Barbara; Swandari, Swestika; Fabbri, Alice; Grundy, Quinn; Moynihan, Ray; Bero, Lisa
2018-01-01
Objectives To investigate patterns of industry-sponsored educational events that focus on specific health conditions for which there are concerns about overdiagnosis and overtreatment. Design and setting This retrospective cohort study examines publicly reported industry-sponsored events in Australia from October 2011 to September 2015 for three conditions potentially subject to overdiagnosis and overtreatment: depression, osteoporosis and overactive bladder. We used a database of transparency reports to identify events with a focus on depression, osteoporosis and overactive bladder and compared these with other sponsored events. We hypothesised that companies marketing treatments for each condition would sponsor related events and that target audiences would mainly work in primary care, reflecting a broad patient population. Main outcome measures Event and attendee characteristics, sponsoring companies, related marketed treatments, cost-effectiveness ratings and dispensing rates. Results Over the study period, we identified 1567 events focusing on depression, 1375 on osteoporosis and 190 on overactive bladder (total n=3132, with 96 660 attendees). These events were attended by primary care doctors more often than sponsored events without a focus on these three conditions: relative risk (RR)=3.06 (95% CI 2.81 to 3.32) for depression, RR=1.48 (95% CI 1.41 to 1.55) for osteoporosis and RR=2.59 (95% CI 2.09 to 3.21) for overactive bladder. Servier, which markets agomelatine and AstraZeneca (quetiapine) sponsored 51.2% and 23.0% of depression events, respectively. Amgen and GlaxoSmithKline, which co-market denosumab, sponsored 49.5% of osteoporosis events and Astellas and Commonwealth Serum Laboratories (CSL) (mirabegron and solifenacin) sponsored 80.5% of overactive bladder events. Conclusions This 4-year overview of industry-sponsored events on three overdiagnosed and overtreated conditions found that primary care clinicians were often targeted, dinner was often provided and that a few companies sponsored most events. In most cases, sponsors’ products are not cost-effective choices for the specified condition. This pattern highlights the need for professional education to be free of commercial sponsorship. PMID:29440213
Characteristics of NIH- and industry-sponsored head and neck cancer clinical trials.
Devaiah, Anand; Murchison, Charles
2016-09-01
Compare U.S. clinical trials sponsored by the National Institutes of Health (NIH) and industry, especially with regard to trial design, interventions studied, and results reporting rates. U.S. head and neck cancer clinical trials. We used information from ClinicalTrials.gov to compare NIH- and industry-sponsored head and neck cancer clinical trials, specifically analyzing differences in trial design and interventions studied. We examined publication rates and positive results rates using PubMed.gov. About 50% of NIH- and industry-sponsored clinical trials have their results reported in peer-reviewed literature. Industry-sponsored trials had higher rates of positive results than NIH-sponsored trials. NIH- and industry-sponsored clinical trials had similar trial designs, although industry-sponsored trials had significantly lower rates of randomization. Industry trials utilized radiation in 19% of trials and surgery in 2% of trials. NIH trials also had low utilization of both radiation and surgery (27% and 12% of trials, respectively). NIH- and industry-sponsored trials published their results in journals with comparable impact factors. There is significant underreporting of results in U.S. head and neck cancer clinical trials, whether sponsored by NIH or industry. Industry trials have significantly higher rates of positive results, although it is unclear what contributes to this. Both NIH- and industry-sponsored trials underutilize surgery and radiation as treatment modalities, despite the fact that these are standard-of-care therapies for head and neck cancer. We recommend that the NIH and industry report all results from clinical trials and use surgery and radiation as treatment arms in order to arrive at more balanced therapeutic recommendations. N/A. Laryngoscope, 126:E300-E303, 2016. © 2016 The American Laryngological, Rhinological and Otological Society, Inc.
Evaluating the US Counter-ISIL Strategy
2017-05-25
Evaluating the US Counter-ISIL Strategy A Monograph by LTC Jason A. Curl U.S. Army School of Advanced Military Studies United States Army...SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) Advanced Straegic Leadership Studies Program 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR... studies and they use media very effectively to show the religious legitimacy of their actions. Finally, efforts to prevent the flow of ISIL supporters
Solar energy for process heat: Design/cost studies of four industrial retrofit applications
NASA Technical Reports Server (NTRS)
French, R. L.; Bartera, R. E.
1978-01-01
Five specific California plants with potentially attractive solar applications were identified in a process heat survey. These five plants were visited, process requirements evaluated, and conceptual solar system designs were generated. Four DOE (ERDA) sponsored solar energy system demonstration projects were also reviewed and compared to the design/cost cases included in this report. In four of the five cases investigated, retrofit installations providing significant amounts of thermal energy were found to be feasible. The fifth was rejected because of the condition of the building involved, but the process (soap making) appears to be an attractive potential solar application. Costs, however, tend to be high. Several potential areas for cost reduction were identified including larger collector modules and higher duty cycles.
"Food company sponsors are kind, generous and cool": (mis)conceptions of junior sports players.
Kelly, Bridget; Baur, Louise A; Bauman, Adrian E; King, Lesley; Chapman, Kathy; Smith, Ben J
2011-09-05
Children's exposure to unhealthy food marketing influences their food knowledge, preferences and consumption. Sport sponsorship by food companies is widespread and industry investment in this marketing is increasing. This study aimed to assess children's awareness of sport sponsors and their brand-related attitudes and purchasing intentions in response to this marketing. Sports clubs known to have food sponsors and representing the most popular sports for Australian children across a range of demographic areas were recruited. Interview-based questionnaires were conducted at clubs with children aged 10-14 years (n = 103) to examine their recall of local sports club and elite sport sponsors, and their attitudes towards sponsors and sponsorship activities. Most children (68%) could recall sponsors of their sports club, naming a median of two sponsors, including a median of one food company sponsor each. Almost half (47%) of children could recall any sponsors of their favourite elite sporting team. Children aged 10-11 years were more likely than older children to report that they thought about sponsors when buying something to eat or drink (P < 0.01); that they liked to return the favour to sponsors by buying their products (P < 0.01); and that sponsors were 'cool' (P = 0.02). Most children had received a voucher or certificate from a food or beverage company to reward sport performance (86% and 76%, respectively). Around one-third of children reported liking the company more after receiving these rewards. Children's high recall of food and beverage company sport sponsors and their positive attitudes towards these sponsors and their promotions is concerning as this is likely to be linked to children's food preferences and consumption. Limiting children's exposure to this marketing is an important initiative to improve children's nutrition.
"Food company sponsors are kind, generous and cool": (Mis)conceptions of junior sports players
2011-01-01
Background Children's exposure to unhealthy food marketing influences their food knowledge, preferences and consumption. Sport sponsorship by food companies is widespread and industry investment in this marketing is increasing. This study aimed to assess children's awareness of sport sponsors and their brand-related attitudes and purchasing intentions in response to this marketing. Methods Sports clubs known to have food sponsors and representing the most popular sports for Australian children across a range of demographic areas were recruited. Interview-based questionnaires were conducted at clubs with children aged 10-14 years (n = 103) to examine their recall of local sports club and elite sport sponsors, and their attitudes towards sponsors and sponsorship activities. Results Most children (68%) could recall sponsors of their sports club, naming a median of two sponsors, including a median of one food company sponsor each. Almost half (47%) of children could recall any sponsors of their favourite elite sporting team. Children aged 10-11 years were more likely than older children to report that they thought about sponsors when buying something to eat or drink (P < 0.01); that they liked to return the favour to sponsors by buying their products (P < 0.01); and that sponsors were 'cool' (P = 0.02). Most children had received a voucher or certificate from a food or beverage company to reward sport performance (86% and 76%, respectively). Around one-third of children reported liking the company more after receiving these rewards. Conclusions Children's high recall of food and beverage company sport sponsors and their positive attitudes towards these sponsors and their promotions is concerning as this is likely to be linked to children's food preferences and consumption. Limiting children's exposure to this marketing is an important initiative to improve children's nutrition. PMID:21888675
Industry sponsorship and research outcome.
Lundh, Andreas; Lexchin, Joel; Mintzes, Barbara; Schroll, Jeppe B; Bero, Lisa
2017-02-16
Clinical research affecting how doctors practice medicine is increasingly sponsored by companies that make drugs and medical devices. Previous systematic reviews have found that pharmaceutical-industry sponsored studies are more often favorable to the sponsor's product compared with studies with other sources of sponsorship. A similar association between sponsorship and outcomes have been found for device studies, but the body of evidence is not as strong as for sponsorship of drug studies. This review is an update of a previous Cochrane review and includes empirical studies on the association between sponsorship and research outcome. To investigate whether industry sponsored drug and device studies have more favorable outcomes and differ in risk of bias, compared with studies having other sources of sponsorship. In this update we searched MEDLINE (2010 to February 2015), Embase (2010 to February 2015), the Cochrane Methodology Register (2015, Issue 2) and Web of Science (June 2015). In addition, we searched reference lists of included papers, previous systematic reviews and author files. Cross-sectional studies, cohort studies, systematic reviews and meta-analyses that quantitatively compared primary research studies of drugs or medical devices sponsored by industry with studies with other sources of sponsorship. We had no language restrictions. Two assessors screened abstracts and identified and included relevant papers. Two assessors extracted data, and we contacted authors of included papers for additional unpublished data. Outcomes included favorable results, favorable conclusions, effect size, risk of bias and whether the conclusions agreed with the study results. Two assessors assessed risk of bias of included papers. We calculated pooled risk ratios (RR) for dichotomous data (with 95% confidence intervals (CIs)). Twenty-seven new papers were included in this update and in total the review contains 75 included papers. Industry sponsored studies more often had favorable efficacy results, RR: 1.27 (95% CI: 1.17 to 1.37) (25 papers) (moderate quality evidence), similar harms results RR: 1.37 (95% CI: 0.64 to 2.93) (four papers) (very low quality evidence) and more often favorable conclusions RR: 1.34 (95% CI: 1.19 to 1.51) (29 papers) (low quality evidence) compared with non-industry sponsored studies. Nineteen papers reported on sponsorship and efficacy effect size, but could not be pooled due to differences in their reporting of data and the results were heterogeneous. We did not find a difference between drug and device studies in the association between sponsorship and conclusions (test for interaction, P = 0.98) (four papers). Comparing industry and non-industry sponsored studies, we did not find a difference in risk of bias from sequence generation, allocation concealment, follow-up and selective outcome reporting. However, industry sponsored studies more often had low risk of bias from blinding, RR: 1.25 (95% CI: 1.05 to 1.50) (13 papers), compared with non-industry sponsored studies. In industry sponsored studies, there was less agreement between the results and the conclusions than in non-industry sponsored studies, RR: 0.83 (95% CI: 0.70 to 0.98) (six papers). Sponsorship of drug and device studies by the manufacturing company leads to more favorable efficacy results and conclusions than sponsorship by other sources. Our analyses suggest the existence of an industry bias that cannot be explained by standard 'Risk of bias' assessments.
Mission Command During The Falklands War: Opportunities And Limitations
2016-05-26
Monograph by MAJ Brice Roberts United States Army School of Advanced Military Studies United States Army Command and General Staff College Fort...SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) Advanced Military Studies Program CGSC 11. SPONSOR...This study examines the six principles of mission command, as defined by ADP 6-0, as a lens to evaluate operations conducted by the Landing Force
Association between narcotic use and anabolic-androgenic steroid use among American adolescents.
Denham, Bryan E
2009-01-01
Drawing on the data gathered in the 2006 Monitoring the Future study of American youth, the present research examines associations between use of narcotics and use of anabolic-androgenic steroids (AASs) among high-school seniors (n = 2,489). With independent measures and controls including sex, race, media exposure, socializing with friends, participation in recreational and school-sponsored sports, perceptions of drug use among professional athletes, and perceptions of steroid use among close friends, binary logistic regression analyses revealed significant associations between AAS use and the use of alcohol, crack cocaine, Vicodin, gamma-hydroxybutyrate (GHB), Ketamine, and Rohypnol. While use of both AASs and the narcotic drugs generally did not eclipse 5% of the sample, the numbers extend to many thousands in larger populations. Implications for health practitioners and recommendations for future research are offered. The study's limitations are noted.
NASA Technical Reports Server (NTRS)
Turk, M. A.; Zeiner, P. K.
1986-01-01
In connection with the significant advances made regarding the performance of larger gas turbines, challenges arise concerning the improvement of small gas turbine engines in the 250 to 1000 horsepower range. In response to these challenges, the NASA/Army-sponsored Small Engine Component Technology (SECT) study was undertaken with the objective to identify the engine cycle, configuration, and component technology requirements for the substantial performance improvements desired in year-2000 small gas turbine engines. In the context of this objective, an American turbine engine company evaluated engines for four year-2000 applications, including a rotorcraft, a commuter aircraft, a supersonic cruise missile, and an auxiliary power unit (APU). Attention is given to reference missions, reference engines, reference aircraft, year-2000 technology projections, cycle studies, advanced engine selections, and a technology evaluation.
What is Mine is Yours: The Art of Operational Integration
2016-05-10
United States Army School of Advanced Military Studies United States Army Command and General Staff College Fort Leavenworth, Kansas 2016...9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) School of Advanced Military Studies 11. SPONSOR/MONITOR’S...services or national boundaries. Two contrasting World War II case studies , L TG Patch in southern France and L TG Stilwell in Burma, will be used to
2017-05-25
Wilkinson US Army School of Advanced Military Studies United States Army Command and General Staff College Fort Leavenworth, Kansas 2017 Approved for...SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) Advanced Military Studies Program 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S...adversary’s unconventional threat. To test this framework, this monograph analyzes a case study of how Russia will likely use unconventional forces and
2017-02-15
by LTC (GS) Thomas Kopsch German Army School of Advanced Military Studies United States Army Command and General Staff College Fort Leavenworth...NUMBER 9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) School of Advanced Military Studies 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR...PhD __________________________________, Seminar Leader Eric Laforest, COL ___________________________________, Director, School of Advanced
The Impact of Specialized Telephonic Guides on Employee Engagement in Corporate Well-Being Programs
Barleen, Nathan A.; Marzec, Mary L.; Moloney, Daniel P.; Dobro, Jeff
2018-01-01
Abstract Employer-sponsored well-being programs have been growing in popularity as a means to control rising health care costs and increase workplace productivity. Engagement by employees is necessary for these programs to achieve their desired effects. Extrinsic motivators in the form of incentives and surcharges are commonly introduced by employer program sponsors to promote meaningful engagement. Although these may be successful in achieving a degree of engagement, individuals benefit by being intrinsically motivated as they modify behaviors and improve short- and long-term well-being. Telephonic guides equipped with motivational interviewing and other behavioral strategies to improve engagement may bridge the gap between extrinsic and intrinsic motivation. The objectives of this study are to determine characteristics associated with employee utilization of these guides when offered and to compare subsequent program engagement rates between utilizers to a propensity score matched group of employees who were not offered the service. The data were retrieved from a well-being program provider's database. The study examined 166,258 employees across 35 employers. It found utilizers were older, proportionally more female, in the manufacturing industry, incented to use the guide service, offered a larger incentive for program participation, had healthier self-reported behaviors, and had a higher perception of their employer's focus on well-being. The study found that guide utilizers were significantly more likely to engage in telephonic coaching, digital coaching, and activity tracking up to 6 months. The study's findings suggest telephonic guides using a range of behavioral techniques are an effective strategy to drive well-being program engagement. PMID:28586257
The Impact of Specialized Telephonic Guides on Employee Engagement in Corporate Well-Being Programs.
Boerger, Nicholas L; Barleen, Nathan A; Marzec, Mary L; Moloney, Daniel P; Dobro, Jeff
2018-02-01
Employer-sponsored well-being programs have been growing in popularity as a means to control rising health care costs and increase workplace productivity. Engagement by employees is necessary for these programs to achieve their desired effects. Extrinsic motivators in the form of incentives and surcharges are commonly introduced by employer program sponsors to promote meaningful engagement. Although these may be successful in achieving a degree of engagement, individuals benefit by being intrinsically motivated as they modify behaviors and improve short- and long-term well-being. Telephonic guides equipped with motivational interviewing and other behavioral strategies to improve engagement may bridge the gap between extrinsic and intrinsic motivation. The objectives of this study are to determine characteristics associated with employee utilization of these guides when offered and to compare subsequent program engagement rates between utilizers to a propensity score matched group of employees who were not offered the service. The data were retrieved from a well-being program provider's database. The study examined 166,258 employees across 35 employers. It found utilizers were older, proportionally more female, in the manufacturing industry, incented to use the guide service, offered a larger incentive for program participation, had healthier self-reported behaviors, and had a higher perception of their employer's focus on well-being. The study found that guide utilizers were significantly more likely to engage in telephonic coaching, digital coaching, and activity tracking up to 6 months. The study's findings suggest telephonic guides using a range of behavioral techniques are an effective strategy to drive well-being program engagement.
Publication bias in the pulmonary/allergy literature: effect of pharmaceutical company sponsorship.
Liss, Howard
2006-07-01
A publication bias exists towards positive results in studies funded by pharmaceutical companies. To determine whether drug studies in the pulmonary/allergy literature also demonstrate a publication bias towards more favorable results when a pharmaceutical company funds the study. We reviewed all original articles published in seven pulmonary and allergy journals between October 2002 and September 2003. Included in the review were studies of inhaled corticosteroids (oral or nasal), long- or short-acting bronchodilators, or leukotriene receptor antagonists. Articles with funding from a pharmaceutical company and/or one or more authors employed by a pharmaceutical company were considered pharmaceutical company-sponsored studies. The remaining studies were considered not sponsored by a pharmaceutical company. Results were compared to ascertain whether positive results were obtained more frequently in the company-sponsored studies. Of the 100 articles included in this review 63 were considered pharmaceutical company-sponsored research. Results favorable for the drugs studies were significantly more common in those funded by a pharmaceutical company (98% vs. 32%). In the pulmonary and allergy literature, as in other fields, there is a publication bias towards positive results in pharmaceutical company-sponsored research.
The Defense Science Board 2001 Summer Study on Defense Science and Technology
2002-05-01
SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10 . SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION...Today, it takes roughly 10 to 15 years to develop a safe drug for a specific purpose. The task force believes that it is possible for the United...performance in later screens. DSB Summer Study on Defense Science and Technology ___________________________________________ 10 The
Studies in Intelligence. Volume 54, Number 3, September 2010
2010-09-01
ADDRESS( ES ) Center for the Study of Intelligence,Central Intelligence Agency,Washington,DC,20505 8. PERFORMING ORGANIZATION REPORT NUMBER 9...SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS( ES ) 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION/AVAILABILITY...The Deceivers: Allied Military Deception in the Second World War by Thaddeus Holt •Eyes In The Sky: Eisenhower, The CIA and Cold War Aerial Es
Employer-Sponsored Child Care Models and Related Issues.
ERIC Educational Resources Information Center
Renfroe, Martha Lou
This study was designed to describe the different models of Employer-Sponsored Child Care (ESCC) available to employers and child care professionals. Examples of specific child care programs sponsored by employers are described, and five ESCC models are identified: on-site and off-site centers for a single employer, off-site centers for multiple…
Individual insurance: health insurers try to tap potential market growth.
November, Elizabeth A; Cohen, Genna R; Ginsburg, Paul B; Quinn, Brian C
2009-11-01
Individual insurance is the only source of health coverage for people without access to employer-sponsored insurance or public insurance. Individual insurance traditionally has been sought by older, sicker individuals who perceive the need for insurance more than younger, healthier people. The attraction of a sicker population to the individual market creates adverse selection, leading insurers to employ medical underwriting--which most states allow--to either avoid those with the greatest health needs or set premiums more reflective of their expected medical use. Recently, however, several factors have prompted insurers to recognize the growth potential of the individual market: a declining proportion of people with employer-sponsored insurance, a sizeable population of younger, healthier people forgoing insurance, and the likelihood that many people receiving subsidies to buy insurance under proposed health insurance reforms would buy individual coverage. Insurers are pursuing several strategies to expand their presence in the individual insurance market, including entering less-regulated markets, developing lower-cost, less-comprehensive products targeting younger, healthy consumers, and attracting consumers through the Internet and other new distribution channels, according to a new study by the Center for Studying Health System Change (HSC). Insurers' strategies in the individual insurance market are unlikely to meet the needs of less-than-healthy people seeking affordable, comprehensive coverage. Congressional health reform proposals, which envision a larger role for the individual market under a sharply different regulatory framework, would likely supersede insurers' current individual market strategies.
ERIC Educational Resources Information Center
Papanastasiou, Natalie
2017-01-01
This article presents one of the few qualitative studies to empirically examine the collaboration between private sponsors and principals in the context of England's academy schools policy. It uses the concept of boundary-work to illuminate the multiple dynamics involved in the collaboration between principals and business sponsors. By analysing…
Engaging underserved audiences in informal science education through community-based partnerships
NASA Astrophysics Data System (ADS)
Bouzo, Suzanne
This thesis explores the impact of the Science Education and Engagement of Denver (SEED) Partnership on three of its participant families. The partnership, consisting of large informal science organizations, as well as small community-based organizations, created its programming based on prior research identifying barriers to minority participation in informal science education programs. SEED aims to engage youth and families of emerging populations in science and nature. Three families were examined as a case study to have an in depth investigation about their involvement in the programs sponsored by the partnership. Findings suggest a positive impact on participant feelings and engagement in science and nature. Future recommendations are made for furthering programming as well as conducting a larger scale, more comprehensive program evaluation. This research addresses prior studies that have identified several barriers toward participation of underserved audiences in informal science education programs and how the SEED partnership has addressed specific identified barriers.
Are Hispanics the new ’Threat’? Minority Group Threat and Fear of Crime in Miami-Dade County*
Eitle, David; Taylor, John
2008-01-01
Research examining the determinants of fear of crime has arguably raised more questions than it has answered. This exploratory study addresses one of the compelling questions that remains unanswered: what is the role of ethnicity, both at the community and individual levels, in understanding variation in fear of crime? Guided by racial or minority group threat theory, we examine the relative sizes of both the Black and Latino populations as indicators of minority group threat to determine their role in understanding individual fear of crime in a city where Latinos represent a much larger proportion of the population than Blacks (Miami-Dade County, Florida). Furthermore, the race and ethnic backgrounds of the respondents are also considered to evaluate their role in understanding variation in the fear of crime. Using both Census tract-level data and data collected from a NIDA sponsored grant that was part of a larger study about physically disabled residents, our findings reveal that in Miami-Dade County where Blacks are highly segregated from whites, the relative size of the Latino population is a predictor of fear of crime among white residents. Implications of this finding are considered, including a call for more nuanced research focusing on the predictors of fear of crime within multiethnic communities. PMID:19227693
ERIC Educational Resources Information Center
Bartlett, Kenneth R.; Horwitz, Sujin K.; Ipe, Minu; Liu, Yuwen
2005-01-01
The increase in the number of industry-sponsored credential programs raises many questions for career and technical education. This study investigated the perceived influence of industry-sponsored credentials on the recruitment process in the information technology (IT) field. Influence is examined from the perspective of Human Resource (HR)…
The Energy Economics of Financial Structuring for Renewable Energy Projects
NASA Astrophysics Data System (ADS)
Rana, Vishwajeet
2011-12-01
This dissertation focuses on the various financial structuring options for the renewable energy sector. The projects in this sector are capital-intensive to build but have relatively low operating costs in the long run when compared to traditional energy resources. The large initial capital requirements tend to discourage investors. To encourage renewable investments the government needs to provide financial incentives. Since these projects ultimately generate returns, the government's monetary incentives go to the sponsors and tax equity investors who build and operate such projects and invest capital in them. These incentives are usually in the form of ITCs, PTCs and accelerated depreciation benefits. Also, in some parts of the world, carbon credits are another form of incentive for the sponsors and equity investors to invest in such turnkey projects. The relative importance of these various considerations, however, differs from sponsor to sponsor, investor to investor and from project to project. This study focuses mainly on the US market, the federal tax benefits and incentives provided by the government. This study focuses on the energy economics that are used for project decision-making and parties involved in the transaction as: Project Developer/Sponsor, Tax equity investor, Debt investor, Energy buyer and Tax regulator. The study fulfils the knowledge gap in the decision making process that takes advantage of tax monetization in traditional after-tax analysis for renewable energy projects if the sponsors do not have the tax capacity to realize the total benefits of the project. A case-study for a wind farm, using newly emerging financial structures, validates the hypothesis that these renewable energy sources can meet energy industry economic criteria. The case study also helps to validate the following hypotheses: a) The greater a sponsor's tax appetite, the tower the sponsor's equity dilution. b) The use of leverage increases the cost of equity financing and the financing fee. c) Capital contributions by the sponsor are not relevant to the rate of return (IRR) over the life of the project. Overall conclusion is that financial structures can have a major impact on renewable energy, meeting energy demand in an economic manner. At the end, the dissertation lays down the foundation for future research that can be conducted in this field. Key Words: Renewable energy investments, structured finance, financial structuring
Views of people with schizophrenia regarding aspects of research: study size and funding sources.
Roberts, Laura Weiss; Warner, Teddy D; Hammond, Katherine Green; Hoop, Jinger G
2006-01-01
Serious mental illness research poses many ethical questions, including important considerations pertaining to how large a study is and its source of funding. Little is known about how people with schizophrenia understand these ethical considerations and whether these factors may influence their decisions to participate in research. Structured interviews were conducted with 60 people with schizophrenia. Participants were asked about levels of suffering and the importance of research for healthy people and for people with serious illnesses. Participants also rated helpfulness and harmfulness to society, and their likelihood of participating in studies involving 10 subjects, 1000 subjects, 1 research institution, or 10 research institutions and in studies funded by various organizations. Participants viewed all types of research positively and indicated willingness to volunteer. Likelihood of participating in research was correlated with perceived helpfulness to society and inversely correlated with perceived harmfulness. Research by pharmaceutical companies was seen as less helpful to society than research sponsored by federal or state government or by private foundations. Larger studies conducted at multiple sites were seen as more helpful to society than smaller studies or those at single sites. Larger studies conducted at single sites, however, were seen as more harmful. Respondents endorsed a positive view of medical research and expressed a willingness to participate in projects of all scales with diverse funding sources. The pattern of responses suggests the capacity for a nuanced understanding of ethically salient aspects of medical research by individuals with schizophrenia.
ERIC Educational Resources Information Center
Howard, E. Marguerite, Ed.
A guide to summer study abroad is presented with information on how to plan rewarding summer study and travel overseas. Concise descriptions of over 1300 postsecondary study programs worldwide (in over 65 countries) sponsored by U.S. and foreign universities and institutions are included with details on program sponsor and name, location, dates,…
Hughes, Andrew; Landers, Donal; Arkenau, Hendrik-Tobias; Shah, Saj; Stephens, Richard; Mahal, Amrik; Simmons, Matthew; Lemech, Charlotte; Royle, Jennifer
2016-06-01
During early clinical testing of a new medication, it is critical to understand and characterise patient tolerability. However, in early clinical studies, it is difficult for patients to contribute directly to the sponsors' understanding of a new compound. Patient reported opinions about clinical tolerability (PROACT) provides a new, simple and innovative way in which patients can collaborate using an application downloaded to a mobile computer or smartphone. PROACT was designed with special consideration given to patient confidentiality, patient engagement and data security. A pilot study was conducted to investigate patient uptake of PROACT and to characterize clinical trial information it captured. Patients recruited to Phase I oncology trials at a UK center were eligible to participate but were required to have a tablet computer or smartphone. Patients used PROACT to upload audio/video messages that became available instantly to their clinical team, who were able to reply to the patient within PROACT. The patient's message was also analyzed, personally-identifiable information removed and anonymized information then made available to the sponsor in an analytics module for decision-making. In parallel, a patient focus group was engaged to provide feedback on communication needs during early clinical trials and the PROACT concept. Of the 16 patients informed of PROACT, 8 had a smart device and consented to take part. Use of PROACT varied and all messages volunteered were relevant and informative for drug development. Topics disclosed included tolerability impacts, study design, and drug formulation. Alignment with the clinical study data provided a richer understanding of tolerability and treatment consequences. This information was available to be shared among the clinical team and the sponsor, to improve patient support and experience. Patient forum feedback endorsed the concept and provided further information to enhance the application. Overall, PROACT achieved proof of concept in this small pilot study and delivered a secure end-to-end system that protected patient privacy and provided preliminary insight into patient experiences beyond the usual clinical trial data set. The use of mobile devices to interact actively with participants in clinical trials may be a new way of engaging and empowering patients. Further validation of this technology in larger patient cohorts is ongoing. AstraZeneca.
RLE progress report no. 133, 1 January - 31 December 1990
NASA Technical Reports Server (NTRS)
Allen, Jonathan; Kleppner, Daniel; Ziegler, Mary J. (Editor); Passero, Barbara (Editor)
1990-01-01
Activities of the Research Laboratory of Electronics at MIT are summarized. NASA-sponsored research in the area of synthetic aperture radar image interpretation and simulation is described. Other government-sponsored and industry-sponsored studies are also described which address the following topics: microwave and millimeter wave integrated circuits, high-speed integrated circuit interconnects, Instrument Landing System/Microwave Landing System frequency management assessment, and superconducting electronics.
Dynamics of Vorticity Defects in Stratified Shear
2010-10-19
NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Woods Hole Oceanographic Institution,Woods Hole,MA,02543 8... PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT...provided integral dispersion relationships. Next Lerner and Knobloch[24] performed long-wavelength stability studies on a distorted Couette flow. The
Introduction to the focus issue: fifty years of chaos: applied and theoretical.
Hikihara, Takashi; Holmes, Philip; Kambe, Tsutomu; Rega, Giuseppe
2012-12-01
The discovery of deterministic chaos in the late nineteenth century, its subsequent study, and the development of mathematical and computational methods for its analysis have substantially influenced the sciences. Chaos is, however, only one phenomenon in the larger area of dynamical systems theory. This Focus Issue collects 13 papers, from authors and research groups representing the mathematical, physical, and biological sciences, that were presented at a symposium held at Kyoto University from November 28 to December 2, 2011. The symposium, sponsored by the International Union of Theoretical and Applied Mechanics, was called 50 Years of Chaos: Applied and Theoretical. Following some historical remarks to provide a background for the last 50 years, and for chaos, this Introduction surveys the papers and identifies some common themes that appear in them and in the theory of dynamical systems.
Revisiting financial conflicts of interest in FDA advisory committees.
Pham-Kanter, Genevieve
2014-09-01
The Food and Drug Administration (FDA) Safety and Innovation Act has recently relaxed conflict-of-interest rules for FDA advisory committee members, but concerns remain about the influence of members' financial relationships on the FDA's drug approval process. Using a large newly available data set, this study carefully examined the relationship between the financial interests of FDA Center for Drug Evaluation and Research (CDER) advisory committee members and whether members voted in a way favorable to these interests. The study used a data set of voting behavior and reported financial interests of 1,379 FDA advisory committee members who voted in CDER committee meetings that were convened during the 15-year period of 1997-2011. Data on 1,168 questions and 15,739 question-votes from 379 meetings were used in the analyses. Multivariable logit models were used to estimate the relationship between committee members' financial interests and their voting behavior. Individuals with financial interests solely in the sponsoring firm were more likely to vote in favor of the sponsor than members with no financial ties (OR = 1.49, p = 0.03). Members with interests in both the sponsoring firm and its competitors were no more likely to vote in favor of the sponsor than those with no financial ties to any potentially affected firm (OR = 1.16, p = 0.48). Members who served on advisory boards solely for the sponsor were significantly more likely to vote in favor of the sponsor (OR = 4.97, p = 0.005). There appears to be a pro-sponsor voting bias among advisory committee members who have exclusive financial relationships with the sponsoring firm but not among members who have nonexclusive financial relationships (ie, those with ties to both the sponsor and its competitors). These findings point to important heterogeneities in financial ties and suggest that policymakers will need to be nuanced in their management of financial relationships of FDA advisory committee members. © 2014 Milbank Memorial Fund.
[Analysis of projects of schistosomiasis sponsored by National Science Foundation of China].
Wen-di, Zhou; Liang, Shi; Xue-Dan, Ke; Jie, Wang
2017-07-27
To summarize the present development by analysis of projects in schistosomiasis funded by National Science Foundation of China (NSFC). Based on the ISIS database of NFSC, the projects in the studies of schistosomiasis from 2005 to 2016 were analyzed. The distributions of sponsored numbers, amounts, types, agencies, disciplines and changes in research topics by means of network profiles were described. During the study period, 198 projects were funded by NSFC totally with 76.05 million yuan in which the general and youth projects were main types. The main sponsored agencies were research institutes and medical colleges. The top three fields sponsored were medical pathogenic microbes and infection, veterinary and medical immunology. The funding on schistosomiasis researches has a downward trend, but studies are continuing in depth. In this situation, innovative and interdisciplinary researches need to be encouraged to promote the development of schistosomiasis.
A Study of Topic and Topic Change in Conversational Threads
2009-09-01
AUTHOR(S) 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS( ES ) 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING / MONITORING AGENCY NAME(S) AND...ADDRESS( ES ) 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION / AVAILABILITY STATEMENT 13. SUPPLEMENTARY NOTES...unigrams. By converting documents to a vector space representations, the tools of geometry and algebra can be applied, and questions of difference
Great Power Concert: Competition, Cooperation, and Stability in East Africa
2013-06-01
PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) School Of Advanced Air And Space Studies,,Air University,,Maxwell Air Force Base,,AL 8. PERFORMING... ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT...alliances. Establishing international institutions like the United Nations and the North Atlantic Treaty Organization during the post-World War II era, the
Unfulfilled translation opportunities in industry sponsored clinical trials.
Smed, Marie; Getz, Kenneth A
2013-05-01
Knowledge generated by site representatives through their participation in clinical trials is valuable for testing new products in use and obtaining final market approval. The leverage of this important knowledge is however challenged as the former direct relationships between in-house staff in the industry and site representatives are changing. The process of clinical trials has increased in complexity over the years, resulting in additional management layers. Besides an increase in internal management layers, sponsors often also outsource various tasks related to clinical trials to a CRO (Contract Research Organization) and thereby adding another link in the relationships between site and sponsor. These changes are intended to optimize the time-consuming and costly trial phases; however, there is a need to study whether valuable knowledge and experience is compromised in the process. Limited research exists on the full range of clinical practice insights obtained by investigators during and after clinical trials and how well these insights are transferred to study sponsors. This study explores the important knowledge-transfer processes between sites and sponsors and to what extent sites' knowledge gained in clinical trials is utilized by the industry. Responses from 451 global investigative site representatives are included in the study. The analysis of the extensive dataset reveals that the current processes of collaboration between sites and the industry restrict the leverage of valuable knowledge gained by physicians in the process of clinical trials. These restrictions to knowledge-transfer between site and sponsor are further challenged if CRO partners are integrated in the trial process. Copyright © 2013 Elsevier Inc. All rights reserved.
Jian-Ming, Wang; Yan-Kai, Xia; Hui-Juan, Zhu; Feng, Chen; Hong-Bing, Shen
2016-05-10
To analyze the projects on the infectious disease epidemiology sponsored by the National Natural Science Foundation of China (NSFC), explore the hotspot and development trend, and offer a reference for researchers in this field. Based on the NSFC database, the projects on the infectious disease epidemiology (H2609) sponsored from 1987 to 2014 were analyzed. The changes of fund numbers, amounts and research fields were described. During the study period, NSFC sponsored 373 projects, including 228 general projects (61.1%), 78 youth projects (20.9%) and 67 other projects (18.0%). The average amount of the grant was 358.2 thousand Yuan (20 thousand-8 million). The main sponsored research fields were mechanisms of pathogen and immunity (36.2%) and population-based epidemiological studies (33.0%). The top three diseases were hepatitis, HIV/AIDS and tuberculosis. The amount of funding on researches of infectious disease epidemiology has increased continuously, which has played an important role in training scientific talents in the field of prevention and control of infectious diseases.
2016-03-01
CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT...NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBER 9...SPONSORING / MONITORING AGENCY NAME( S ) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM( S ) 11. SPONSOR/MONITOR’S REPORT NUMBER( S ) 12
Shallow Water Acoustics Studies
2017-11-19
0040 00014-16-1-236 I entitled · hallow Water Acou ti Tudies" Principal Inv tigator Dr. James F. Lynch inceret . I ...J’ _,....: ..;._ / 0 ’ 1...NUMBER Woods Hole Oceanographic Institution 98 Water Street Woods Hole, MA 02543-1053 9. SPONSORING/ MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10...SPONSOR/MONITOR’S ACRONYM(S) Dr. Robert Headrick ONR Office of Naval Research Code 322 11 . SPONSOR/MONITOR’S REPORT 875 North Randolph Street NUMBER
Studies in Intelligence. Volume 58, Number 3 (Unclassified Articles from September 2014)
2014-09-01
tics offi cer, presumably responsible for maintaining the quality of the technical data on Japanese radars and radios the unit collected. 11 ...NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11 . SPONSOR/MONITOR’S REPORT NUMBER(S) 12...Intelligence welcomes articles, book reviews, and other communications . Hardcopy material or data discs (preferably in .doc or .rtf formats) may be mailed to
Defense AT&L. Volume 43, Number 6, November-December 2014
2014-12-01
ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11 . SPONSOR/MONITOR’S REPORT NUMBER(S...Agency. The basic idea was to combine wide-area surveillance, networked Com- mand, Control and Communications , and precision munitions into an...start to IOC. In 1996, this metric had grown to 11 years. A more recent Government Accountability Office study (GAO-14-145T) highlighted that the
Anti-satellite Weapons, Deterrence and Sino-American Space Relations
2013-09-01
REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11 . SPONSOR/MONITOR’S REPORT NUMBER(S) 12...DTRA). The project also wishes to thank Stimson’s Communications team-David Egner and Rich Robinson-copy editor Nancy Lewis, designer Neal Ashby, and...payloads with ever-greater capabilities. Scientific study, helped by access to space, flourished. Civil and military use of space-based communications
Solomon, Andrew J; Klein, Eran P; Corboy, John R; Bernat, James L
2015-10-01
Pharmaceutical industry financial support of physicians, physician practices, and academic departments involved in multicenter industry-sponsored clinical trials of novel therapeutic agents is a relatively new and infrequently acknowledged source of potential physician conflict of interest. Detailed disclosure of these relationships to study participants is not uniformly a part of informed consent and documentation practices. To understand attitudes of patients with multiple sclerosis concerning disclosure of potential physician-industry conflicts of interest created by clinical trials and how such disclosures may influence study participation An anonymous online instrument was developed. 597 people with multiple sclerosis participated in the study. The study found that detailed disclosure of conflicts of interest is important to potential participants in industry-sponsored clinical trials for multiple sclerosis therapies and that the presence of these conflicts of interest may influence patients' decisions to participate in these studies. Findings from this study support a call for uniform guidelines regarding disclosure of physician-industry relationships to prospective research participants for industry-sponsored clinical trials. © The Author(s), 2015.
ERIC Educational Resources Information Center
Ahmad, Ahmad Bayiz; Hassan, Hemin Ali; Al-Ahmedi, Mustafa Wshyar Abdulla
2017-01-01
This study examines the motivations of government-sponsored Kurdish students to study abroad and the reasons for choosing a particular country as their destination choice. Based on data we collected through an online survey and follow-up interviews, we compare demographic differences to explore the diversity among this cohort. The findings of the…
Gobbini, Elisa; Pilotto, Sara; Pasello, Giulia; Polo, Valentina; Di Maio, Massimo; Arizio, Francesca; Galetta, Domenico; Petrillo, Patrizia; Chiari, Rita; Matocci, Roberta; Di Costanzo, Alessandro; Di Stefano, Teresa Severina; Aglietta, Massimo; Cagnazzo, Celeste; Sperduti, Isabella; Bria, Emilio; Novello, Silvia
2018-03-01
Contract research organization (CRO) support is largely included in clinical trial management, although its effect in terms of time savings and benefit has not yet been quantified. We performed a retrospective multicenter analysis of lung cancer trials to explore differences in term of trial activation timelines and accrual for studies with and without CRO involvement. Results regarding study timelines from feasibility data to first patient enrollment were collected from 7 Italian thoracic oncology departments. The final accruals (screened/enrolled patients) are reported. We considered CRO/sponsor-administered and CRO-free trials according to who was responsible for the management of the crucial setup phases. Of 113 trials, 62 (54.9%) were CRO-administered, 34 (30.1%) were sponsor-administered, and 17 (15.0%) were CRO-free. The median time from feasibility invitation to documentation obtainment was 151 days in the CRO-administered trials versus 128 in the sponsor-administered and 120 in the CRO-free trials. The time from document submission to contract signature was 142 days in the CRO-administered versus 128 in the sponsor-administered and 132 in the CRO-free trials. The time from global accrual opening to first patient enrollment was 247 days for the CRO-administered versus 194 in the sponsor-administered and 151 in the CRO-free trials. No significant differences were observed in terms of the median overall timeline: 21 months in the CRO-administered, 15 in the sponsor-administered, and 18 months in the CRO-free studies (P = .29). Although no statistically significant differences were identified, the results of our analysis support the idea that bureaucratic procedures might require more time in CRO-administered trials than in sponsor-administered and CRO-free studies. This bureaucratic delay could negatively affect Italian patients' screening and enrollment compared with other countries. Copyright © 2017 Elsevier Inc. All rights reserved.
Congruence and placement in sponsorship: An eye-tracking application.
Alonso Dos Santos, Manuel; Calabuig Moreno, Ferran; Sánchez Franco, Manuel
2018-05-30
Sporting events can be announced using sports posters and by disseminating advertisements on the internet, on the street and in print media. But until now, no prior research has measured the effectiveness of sponsorship in sporting event posters. This study uses eye tracking to measure the effectiveness of sporting event posters and proposes considering the level of the viewer's attention as an indicator. This research involves a factorial experiment based on the following variables: congruence, the number of sponsors, and placement of the sponsor's advertisement in a sporting event poster. The results indicate that sponsors positioned in the poster's area of action receive more attention. However, we were unable to prove that congruent sponsors receive more attention, as claimed in the literature. This result could be due to a situation of blindness towards the sponsor. The conclusion section of this paper discusses theoretical conclusions and potential managerial actions. Copyright © 2018 Elsevier Inc. All rights reserved.
Rosenberg, N J; Siegel, M
2001-09-01
To describe the nature and extent of tobacco company sponsorship in the USA during the period 1995-99 and analyse this sponsorship in a marketing context. A cross-sectional study of tobacco company sponsorships identified through a customised research report from IEG Inc, and from internet web site searches. First, a customised report was received from IEG Inc, which identified sponsorship activities for Philip Morris, RJ Reynolds, Brown & Williamson, Lorillard, and US Tobacco for the years 1997 and 1998. Second, the internet was systematically searched for tobacco industry sponsorships during the period 1995-99 by the same parent companies and their respective brands. During the period 1995-99, tobacco companies sponsored at least 2733 events, programmes, and organisations in the USA. Sponsorships involved all 50 states and the District of Columbia, and the minimum total funding amount of these sponsorships was $365.4 million. Tobacco corporate sponsorships involved numerous small, community based organisations, both through direct funding and through grants to larger umbrella organisations, and many of these organisations were part of the public health infrastructure. Tobacco corporate sponsorship serves as an important marketing tool for tobacco companies, serving both a sales promotion and public relations function. Public health practitioners need to develop better surveillance systems for monitoring tobacco sponsorship, to seek out alternative funding sources for tobacco company sponsored events and organisations, and to consider promoting a ban on tobacco sponsorship, possibly linking such regulation to the creation of alternative funding sources.
7 CFR 654.11 - Sponsor(s)' responsibility.
Code of Federal Regulations, 2010 CFR
2010-01-01
...) shall obtain NRCS approval before modifying a project measure of changing land use to fulfill a... § 654.11 Sponsor(s)' responsibility. (a) On non-Federal land, sponsor(s) are responsible for financing... land involving project measures is responsible either for performing or requiring the performance of O...
Code of Federal Regulations, 2013 CFR
2013-01-01
... AGRICULTURE WATER RESOURCES WATERSHED PROJECTS Qualifications § 622.10 Sponsors. (a) Watershed projects are sponsored by one or more local organizations qualifying as sponsors. All watershed plans shall be sponsored...
Code of Federal Regulations, 2012 CFR
2012-01-01
... AGRICULTURE WATER RESOURCES WATERSHED PROJECTS Qualifications § 622.10 Sponsors. (a) Watershed projects are sponsored by one or more local organizations qualifying as sponsors. All watershed plans shall be sponsored...
Code of Federal Regulations, 2011 CFR
2011-01-01
... AGRICULTURE WATER RESOURCES WATERSHED PROJECTS Qualifications § 622.10 Sponsors. (a) Watershed projects are sponsored by one or more local organizations qualifying as sponsors. All watershed plans shall be sponsored...
Code of Federal Regulations, 2014 CFR
2014-01-01
... AGRICULTURE WATER RESOURCES WATERSHED PROJECTS Qualifications § 622.10 Sponsors. (a) Watershed projects are sponsored by one or more local organizations qualifying as sponsors. All watershed plans shall be sponsored...
2008-01-01
S ) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) U.S. Air Force Academy,Institute...for National Security Studies,USAFA,CO,80840 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME( S ) AND ADDRESS(ES) 10...SPONSOR/MONITOR’S ACRONYM( S ) 11. SPONSOR/MONITOR’S REPORT NUMBER( S ) 12. DISTRIBUTION/AVAILABILITY STATEMENT Approved for public release; distribution
Dias, Sofia; Ades, A E
2014-01-01
Objective To explore the risk of industry sponsorship bias in a systematically identified set of placebo controlled and active comparator trials of statins. Design Systematic review and network meta-analysis. Eligibility Open label and double blind randomised controlled trials comparing one statin with another at any dose or with control (placebo, diet, or usual care) for adults with, or at risk of developing, cardiovascular disease. Only trials that lasted longer than four weeks with more than 50 participants per trial arm were included. Two investigators assessed study eligibility. Data sources Bibliographic databases and reference lists of relevant articles published between 1 January 1985 and 10 March 2013. Data extraction One investigator extracted data and another confirmed accuracy. Main outcome measure Mean absolute change from baseline concentration of low density lipoprotein (LDL) cholesterol. Data synthesis Study level outcomes from randomised trials were combined using random effects network meta-analyses. Results We included 183 randomised controlled trials of statins, 103 of which were two-armed or multi-armed active comparator trials. When all of the existing randomised evidence was synthesised in network meta-analyses, there were clear differences in the LDL cholesterol lowering effects of individual statins at different doses. In general, higher doses resulted in higher reductions in baseline LDL cholesterol levels. Of a total of 146 industry sponsored trials, 64 were placebo controlled (43.8%). The corresponding number for the non-industry sponsored trials was 16 (43.2%). Of the 35 unique comparisons available in 37 non-industry sponsored trials, 31 were also available in industry sponsored trials. There were no systematic differences in magnitude between the LDL cholesterol lowering effects of individual statins observed in industry sponsored versus non-industry sponsored trials. In industry sponsored trials, the mean change from baseline LDL cholesterol level was on average 1.77 mg/dL (95% credible interval −11.12 to 7.66) lower than the change observed in non-industry sponsored trials. There was no detectable inconsistency in the evidence network. Conclusions Our analysis shows that the findings obtained from industry sponsored statin trials seem similar in magnitude as those in non-industry sources. There are actual differences in the effectiveness of individual statins at various doses that explain previously observed discrepancies between industry and non-industry sponsored trials. PMID:25281681
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-26
... Water District, sponsor of the study, has recently requested the study be suspended until a later date... sponsoring the project. In 2000, the River Valley Regional Water District identified themselves as a willing... under the direction of the U.S. Congress. The study would have consisted of major hydraulics and...
THE EFFECT OF TAX PREFERENCES ON HEALTH SPENDING
Cogan, John F.; Hubbard, R. Glenn; Kessler, Daniel P.
2011-01-01
In this paper, we estimate the effect of the tax preference for health insurance on health care spending using data from the Medical Expenditure Panel Surveys from 1996–2005. We use the fact that Social Security taxes are only levied on earnings below a statutory threshold to identify the impact of the tax preference. Because employer-sponsored health insurance premiums are excluded from Social Security payroll taxes, workers who earn just below the Social Security tax threshold receive a larger tax preference for health insurance than workers who earn just above it. We find a significant effect of the tax preference, consistent with previous research. PMID:22500056
Community smoking cessation contests: an effective public health strategy.
Leinweber, C E; Macdonald, J M; Campbell, H S
1994-01-01
This report describes the follow-up of a community-sponsored smoking cessation contest. The aims of the evaluation were to describe the characteristics of contestants and the quit rates at six weeks, six months and one year. The "Quit to Win" contest was held as part of a larger cancer prevention program in Medicine Hat, Alberta. In order to be eligible for prizes, contestants were required to be smoke-free for six weeks and have their smoking status verified by a "Buddy". Contestants were contacted by telephone at the end of the contest and again at six months and one year. Seventy-five individuals entered the contest. The quit rates, 56%, 27% and 21% at six weeks, six months and one year respectively, compare favourably with other smoking cessation interventions. This study demonstrates that a community-based program can reach a variety of smokers with a relatively simple intervention.
NASA Astrophysics Data System (ADS)
Orna, Mary Virginia
1999-09-01
We are in the era of Big Science, which also means big institutions where the Big Science is done. However, higher education in the United States is unique in that parallel to the array of big institutions is a system of small liberal arts and sciences colleges where students receive the personal attention and faculty contact that is often not possible at larger institutions. While these smaller institutions are limited in resources and finances, studies have shown that they contribute a disproportionately higher number of leaders across a spectrum of disciplines, including chemistry. This address summarizes my personal odyssey and the reasons for the award. In it, I emphasize the advantages enjoyed by liberal arts and sciences students and faculty that enable them to overcome the view that great things can only be done in large, cosmopolitan settings.
Analysis of Dependencies and Impacts of Metroplex Operations
NASA Technical Reports Server (NTRS)
DeLaurentis, Daniel A.; Ayyalasomayajula, Sricharan
2010-01-01
This report documents research performed by Purdue University under subcontract to the George Mason University (GMU) for the Metroplex Operations effort sponsored by NASA's Airportal Project. Purdue University conducted two tasks in support of the larger efforts led by GMU: a) a literature review on metroplex operations followed by identification and analysis of metroplex dependencies, and b) the analysis of impacts of metroplex operations on the larger U.S. domestic airline service network. The tasks are linked in that the ultimate goal is an understanding of the role of dependencies among airports in a metroplex in causing delays both locally and network-wide. The Purdue team has formulated a system-of-systems framework to analyze metroplex dependencies (including simple metrics to quantify them) and develop compact models to predict delays based on network structure. These metrics and models were developed to provide insights for planners to formulate tailored policies and operational strategies that streamline metroplex operations and mitigate delays and congestion.
Anti-tobacco television advertising and indicators of smoking cessation in adults: a cohort study.
Hyland, A; Wakefield, M; Higbee, Cheryl; Szczypka, G; Cummings, K M
2006-04-01
The objective of this study was to assess the relationship between exposure to state-sponsored anti-tobacco advertising and smoking cessation. Cessation rates in 2001 among a cohort of 2061 smokers who participated in the Community Intervention Trial for Smoking Cessation between 1988 and 1993 and completed a follow-up survey in 2001 were merged with the 2000-01 television advertising exposure data from Nielsen Media Research. The relative risk for quitting was estimated to be 10% higher for every 5000 units of exposure to state anti-tobacco television advertising over the 2-year period, although this did not quite achieve statistical significance. The association was even larger among those who reported that the level of information in the media about the dangers of smoking had increased 'a lot' between 1993 and 2001 (RR = 1.19, 95% CI = 1.03-1.38). These data are consistent with the finding that increased exposure to state anti-tobacco media increases smoking cessation rates.
Anti-tobacco television advertising and indicators of smoking cessation in adults: a cohort study.
Hyland, A; Wakefield, M; Higbee, Cheryl; Szczypka, G; Cummings, K M
2006-06-01
The objective of this study was to assess the relationship between exposure to state-sponsored anti-tobacco advertising and smoking cessation. Cessation rates in 2001 among a cohort of 2061 smokers who participated in the Community Intervention Trial for Smoking Cessation between 1988 and 1993 and completed a follow-up survey in 2001 were merged with 2000-01 television advertising exposure data from Nielsen Media Research. The relative risk for quitting was estimated to be 10% higher for every 5000 units of exposure to state anti-tobacco television advertising over the 2-year period, although this did not quite achieve statistical significance. The association was even larger among those who reported that the level of information in the media about the dangers of smoking had increased 'a lot' between 1993 and 2001 (RR = 1.19, 95% CI = 1.03-1.38). These data are consistent with the finding that increased exposure to state anti-tobacco media increases smoking cessation rates.
ERIC Educational Resources Information Center
Perna, Laura W.; Orosz, Kata; Jumakulov, Zakir; Kishkentayeva, Marina; Ashirbekov, Adil
2015-01-01
Although prior research establishes the forces that "push" and "pull" students to participate in foreign study, the transferability of findings from earlier studies is limited by the absence of theoretical grounding. In addition, relatively little is known about how a government-sponsored student mobility program promotes…
ERIC Educational Resources Information Center
Ma, Jennifer; Warshawsky, Mark J.; Ameriks, John; Blohm, Julia A.
This study used an expected utility framework with a mean-lower partial moment specification for investor utility to determine the asset allocation and the allowable contribution limits for qualified state-sponsored tuition savings plans. Given the assumptions about state policymakers' perceptions of investor utility, the study determined the…
Undergraduates' Perceptions of Conflict of Interest in Industry-Sponsored Research
ERIC Educational Resources Information Center
Perry, Heather Brodie
2018-01-01
The prevalence of industry-sponsored research has led to significant concerns about financial conflicts of interest and the impact on research findings. This case study sought to examine how students considered conflict of interest when establishing the cognitive authority of a journal article. The case study used a mixed methods pretest and…
Powell-Smith, Anna; Goldacre, Ben
2016-01-01
Background : Failure to publish trial results is a prevalent ethical breach with a negative impact on patient care. Audit is an important tool for quality improvement. We set out to produce an online resource that automatically identifies the sponsors with the best and worst record for failing to share trial results. Methods: A tool was produced that identifies all completed trials from clinicaltrials.gov, searches for results in the clinicaltrials.gov registry and on PubMed, and presents summary statistics for each sponsor online. Results : The TrialsTracker tool is now available. Results are consistent with previous publication bias cohort studies using manual searches. The prevalence of missing studies is presented for various classes of sponsor. All code and data is shared. Discussion: We have designed, built, and launched an easily accessible online service, the TrialsTracker, that identifies sponsors who have failed in their duty to make results of clinical trials available, and which can be maintained at low cost. Sponsors who wish to improve their performance metrics in this tool can do so by publishing the results of their trials.
Setting health care priorities: Oregon's next steps.
Dougherty, Charles J
1991-01-01
Since the proposal was first broached in 1987, a storm of controversy has engulfed Oregon's plan to prioritize the health care services offered to its Medicaid recipients. After two years of debate, community consultation, and public opinion polls, the Oregon Health Services Commission was mandated in 1989 to study prioritization as part of a package of bills enacted as the Oregon Basic Health Services Act. In March 1990 the commission released a draft list of ranked health care services for public comment... As part of the ongoing debate, the Hastings Center and the Wesley Foundation sponsored a two-day meeting in January 1991 in Wichita, Kansas, to provide opportunity for thoughtful, in-depth, informal analysis of the OBHSA model for health care reform...a majority felt that OBHSA, in the framework of progress toward larger reform goals, is an experiment worth trying. Some felt that even if OBHSA doesn't attain its larger goals it should be tried since it will extend access and may lead to better health outcomes among the poor. But the general view was that OBHSA is a valuable experiment only to the extent that it leads to a statewide system of universal health insurance in Oregon without creating special burdens for the state's poor....
Unhealthy product sponsorship of Australian national and state sports organisations.
Macniven, Rona; Kelly, Bridget; King, Lesley
2015-04-01
Marketing of products harmful to the health of children has been found to be prolific, and occurs across multiple media platforms and in several settings, including organised sport, thus potentially undermining the health benefits inherent in sports participation. Through website audits, this study investigated the nature and extent of unhealthy food, beverage, alcohol and gambling sponsorship across peak Australian sporting organisations. A structured survey tool identified and assessed sponsoring companies and products displayed on the websites of the 53 national and state/territory sport governing bodies in Australia receiving government funding. Identified products were categorised as healthy or unhealthy, based on criteria developed by health experts. There was a total of 413 websites operated by the 53 sports, with 1975 company or product sponsors identified. Overall, 39 sports had at least one unhealthy sponsor, and 10% of all sponsors were rated as unhealthy. Cricket had the highest percent of unhealthy sponsors (27%) and the highest number of unhealthy food and beverage sponsors (n=19). Rugby Union (n=16) and Australian Football (n=4) had the highest numbers of alcohol and gambling sponsors respectively. Sponsorship of Australian sport governing bodies by companies promoting unhealthy food and beverage, alcohol and gambling products is prevalent at the state/territory and national level. SO WHAT?: Regulatory guidelines should be established to limit such sponsorship and ensure that it is not translated into promotions that may reach and influence children.
ERIC Educational Resources Information Center
Thot, Iris Dolores
This study examined the effects of study abroad on college students participating in the Congress-Bundestag Youth Exchange, sponsored 60 percent by the German government and 40 percent by the U.S. government. The study's main context focused on the problem that American-sponsored programs (in which over 80 percent of study- abroad students…
A Victorious Defeat: Mission Command Failure of the 1857-1858 Utah Expedition
2016-05-26
States Army School of Advanced Military Studies United States Army Command and General Staff College Fort Leavenworth, Kansas 2016...MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) Advanced Military Studies Program 11. SPONSOR/MONITOR’S REPORT...Director, School of Advanced Military Studies Henry A. Arnold III, COL Accepted this 10th day of May
ERIC Educational Resources Information Center
Yego, Helen J. C.
2016-01-01
This paper examines the expansion and management of quality of parallel programmes in Kenya's public universities. The study is based on Privately Sponsored Students Programmes (PSSP) at Moi University and its satellite campuses in Kenya. The study was descriptive in nature and adopted an ex-post facto research design. The study sample consisted…
NASA Astrophysics Data System (ADS)
Single, Peg Boyle; Muller, Carol B.; Cunningham, Christine M.; Single, Richard M.
In this article, we report on electronic discussion lists (e-lists) sponsored by MentorNet, the National Electronic Industrial Mentoring Network for Women in Engineering and Science. Using the Internet, the MentorNet program connects students in engineering and science with mentors working in industry. These e-lists are a feature of MentorNet's larger electronic mentoring program and were sponsored to foster the establishment of community among women engineering and science students and men and women professionals in those fields. This research supports the hypothesis that electronic communications can be used to develop community among engineering and science students and professionals and identifies factors influencing the emergence of electronic communities (e-communities). The e-lists that emerged into self-sustaining e-communities were focused on topic-based themes, such as balancing personal and work life, issues pertaining to women in engineering and science, and job searching. These e-communities were perceived to be safe places, embraced a diversity of opinions and experiences, and sanctioned personal and meaningful postings on the part of the participants. The e-communities maintained three to four simultaneous threaded discussions and were sustained by professionals who served as facilitators by seeding the e-lists with discussion topics. The e-lists were sponsored to provide women students participating in MentorNet with access to groups of technical and scientific professionals. In addition to providing benefits to the students, the e-lists also provided the professionals with opportunities to engage in peer mentoring with other, mostly female, technical and scientific professionals. We discuss the implications of our findings for developing e-communities and for serving the needs of women in technical and scientific fields.
Bonfill, Xavier; Ballesteros, Mónica; Gich, Ignasi; Serrano, María Antonia; García López, Fernando; Urrútia, Gerard
2013-01-01
Objective To describe the characteristics of randomized controlled clinical trials (RCT) on cancer drugs conducted in Spain between 1999 and 2003 based on their protocols. Methods We conducted an observational retrospective cohort study to identify the protocols of RCTs on cancer drugs authorized by the Agencia Española del Medicamento y Productos Sanitarios (AEMPS) (Spanish Agency for Medicines and Medical Devices) during 1999-2003. A descriptive analysis was completed and the association between variables based on the study setting and sponsorship were assessed. Results We identified a total of 303 protocols, which included 176,835 potentially eligible patients. Three-quarter of the studies were internationally-based, 61.7% were phase III, and 76.2% were sponsored by pharmaceutical companies. The most frequently assessed outcomes were response rate (24.7%), overall survival (20.7%), and progression-free survival (14.5%). Of all protocols, 10.6% intended to include more than 1000 patients (mean: 2442, SD: 2724). Compared with their national counterparts, internationally-based studies were significantly larger (p<0.001) and were more likely to implement centralized randomization (p<0.001), blinding of the intervention (p<0.001), and survival as primary outcome (p<0.001). Additionally, most internationally-based studies were sponsored by pharmaceutical companies (p<0.01). In a high percentage of protocols, the available information was not explicit enough to assess the validity of each trial. Compared to other European countries, the proportion of Spanish cancer drugs protocols registered at www.clinicaltrials.gov (7%) was lower. Conclusion RCTs on cancer drugs conducted in Spain between 1999 and 2003 were more likely to be promoted by pharmaceutical companies rather than by non-profit national groups. The former were more often part of international studies, which generally had better methodological quality than national ones. There are some worldwide on-going initiatives that aim to increase the transparency and quality of future research. PMID:24236154
48 CFR 970.3501-1 - Sponsoring agreements.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Sponsoring agreements. 970... Sponsoring agreements. (a) The contract award document constitutes the sponsoring agreement between the... the purpose and mission of the FFRDC. (c) Other elements of the sponsoring agreement which shall be...
48 CFR 970.3501-1 - Sponsoring agreements.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Sponsoring agreements. 970... Sponsoring agreements. (a) The contract award document constitutes the sponsoring agreement between the... the purpose and mission of the FFRDC. (c) Other elements of the sponsoring agreement which shall be...
48 CFR 970.3501-1 - Sponsoring agreements.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Sponsoring agreements. 970... Sponsoring agreements. (a) The contract award document constitutes the sponsoring agreement between the... the purpose and mission of the FFRDC. (c) Other elements of the sponsoring agreement which shall be...
Tibau, Ariadna; Anguera, Geòrgia; Andrés-Pretel, Fernando; Templeton, Arnoud J; Seruga, Bostjan; Barnadas, Agustí; Amir, Eitan; Ocana, Alberto
2018-03-13
Clinical research is conducted by academia, cooperative groups (CGs) or pharmaceutical industry. Here, we evaluate the role of CGs and funding sources in the development of guidelines for breast cancer therapies. We identified 94 studies. CGs were involved in 28 (30%) studies while industry either partially or fully sponsored 64 (68%) studies. The number of industry funded studies increased over time (from 0% in 1976 to 100% in 2014; p for trend = 0.048). Only 10 (11%) government or academic studies were identified. Studies conducted by GCs included a greater number of subjects (median 448 vs. 284; p = 0.015), were more common in the neo/adjuvant setting ( p < 0.0001), and were more often randomized ( p = 0.018) phase III ( p < 0.0001) trials. Phase III trial remained significant predictor for CG-sponsored trials (OR 7.1 p = 0.004) in a multivariable analysis. Industry funding was associated with higher likelihood of positive outcomes favoring the sponsored experimental arm ( p = 0.013) but this relationship was not seen for CG-sponsored trials ( p = 0.53). ASCO, ESMO, and NCCN guidelines were searched to identify systemic anti-cancer therapies for early-stage and metastatic breast cancer. Trial characteristics and outcomes were collected. We identified sponsors and/or the funding source(s) and determined whether CGs, industry, or government or academic institutions were involved. Chi-square tests were used for comparison between studies. Industry funding is present in the majority of studies providing the basis for which recommendations about treatment of breast cancer are made. Industry funding, but not CG-based funding, was associated with higher likelihood of positive outcomes in clinical studies supporting guidelines for systemic therapy.
ERIC Educational Resources Information Center
MacDonald, Michael T.
2017-01-01
Literacy "sponsorship" in refugee communities is not without its risks and limitations. For potential sponsors, risks include the commodification of refugee voices, while limits include inaccurate generalizations of those being sponsored. This essay draws from a case study of refugee student discourse to discuss how a more explicit…
Study in the United Kingdom and Ireland, 1987/1988. An IIE Guide to Study Abroad. Second Edition.
ERIC Educational Resources Information Center
Howard, Edrice Marguerite, Ed.
A guide to more than 650 study programs in England, Scotland, Wales, Northern Ireland, and the Republic of Ireland is presented for U.S. students who wish to study abroad. Many of the programs, which range in length up to a full academic year, are sponsored or co-sponsored by the U.S. colleges and universities. The remainder are offered by a…
7 CFR 225.6 - State agency responsibilities.
Code of Federal Regulations, 2010 CFR
2010-01-01
... sponsor's application to participate is denied, the official making the determination of denial must... application submitted by new sponsors and by sponsors which, in the determination of the State agency, have... information sheet for new sponsors and new sites, and for sponsors and sites which, in the determination of...
The State-Sponsored Student Entrepreneur
ERIC Educational Resources Information Center
Mars, Matthew M.; Slaughter, Sheila; Rhoades, Gary
2008-01-01
This paper introduces the emergent role of the state-sponsored student entrepreneur within the academic capitalist knowledge/learning regime. Drawing on two clarifying cases of such entrepreneurship, the study explores the shifting boundaries between public and private sectors, the creation of new circuits of knowledge, and the entrepreneurial…
Baudart, Marie; Ravaud, Philippe; Baron, Gabriel; Dechartres, Agnes; Haneef, Romana; Boutron, Isabelle
2016-01-28
Observational studies are essential for assessing safety. The aims of this study were to evaluate whether results of observational studies evaluating an intervention with safety outcome(s) registered at ClinicalTrials.gov were published and, if not, whether they were available through posting on ClinicalTrials.gov or the sponsor website. We identified a cohort of observational studies with safety outcome(s) registered on ClinicalTrials.gov after October 1, 2007, and completed between October 1, 2007, and December 31, 2011. We systematically searched PubMed for a publication, as well as ClinicalTrials.gov and the sponsor website for results. The main outcomes were the time to the first publication in journals and to the first public availability of the study results (i.e. published or posted on ClinicalTrials.gov or the sponsor website). For all studies with results publicly available, we evaluated the completeness of reporting (i.e. reported with the number of events per arm) of safety outcomes. We identified 489 studies; 334 (68%) were partially or completely funded by industry. Results for only 189 (39%, i.e. 65% of the total target number of participants) were published at least 30 months after the study completion. When searching other data sources, we obtained the results for 53% (n = 158; i.e. 93% of the total target number of participants) of unpublished studies; 31% (n = 94) were posted on ClinicalTrials.gov and 21% (n = 64) on the sponsor website. As compared with non-industry-funded studies, industry-funded study results were less likely to be published but not less likely to be publicly available. Of the 242 studies with a primary outcome recorded as a safety issue, all these outcomes were adequately reported in 86% (114/133) when available in a publication, 91% (62/68) when available on ClinicalTrials.gov, and 80% (33/41) when available on the sponsor website. Only 39% of observational studies evaluating an intervention with safety outcome(s) registered at ClinicalTrials.gov had their results published at least 30 months after study completion. The registration of these observational studies allowed searching other sources (results posted at ClinicalTrials.gov and sponsor website) and obtaining results for half of unpublished studies and 93% of the total target number of participants.
O'Reilly, Erin K; Blair Holbein, M E; Berglund, Jelena P; Parrish, Amanda B; Roth, Mary-Tara; Burnett, Bruce K
2013-12-01
This study highlights Warning Letter (WL) findings issued to sponsor-investigators (S-Is) by the Food and Drug Administration (FDA). The online index of WLs issued from October 1, 2007 through September 30, 2012 was reviewed [1]. Through a manual screening process, letters were evaluated if specifically issued to 'clinical investigators', 'sponsors' or 'sponsor-investigators'. A particular focus was given to S-Is at Academic Health Centres (AHCs). Each letter was scored for the presence of violations in 40 general regulatory categories. A review of FDA WLs issued over a five-year period (FDA Fiscal Years 2008-2012) revealed that WLs to S-Is represent half of the WLs issued to all sponsors (16 of 32 letters). A review of these letters indicates that S-Is are not aware of, or simply do not meet, their regulatory responsibilities as either investigators or sponsors. In comparing total sponsor letters to those of S-Is, the most cited violation was the same: a lack of monitoring. A review of publicly available inspection data indicates that these 16 letters merely represent the tip of the iceberg. This review of the WL database reveals the potential for serious regulatory violations among S-Is at AHCs. Recent translational funding initiatives may serve to increase the number of S-Is, especially among Academic Health Centres (AHCs) [2]; thus, AHCs must become aware of this S-I role and work to support investigators who assume both roles in the course of their research.
What determines hospital sponsorship of an HMO?
McCue, M J
2000-01-01
Using a strategic adaptation framework, this study evaluates the underlying institutional, market, organizational, and financial factors leading to hospital sponsorship of a health maintenance organization (HMO) insurance product. Analyzing hospitals in Metropolitan Statistical Areas (MSAs) in 1995 and 1996, the study found that a hospital is more likely to sponsor an HMO in markets that see a combined interaction effect of a large number of competing HMOs and high HMO penetration. HMO sponsorship also is more likely among hospitals with relatively low market share. Only in small MSA markets do hospitals with greater liquidity sponsor an HMO. Finally, hospitals that are affiliated with a multihospital system and under public ownership are more likely to sponsor HMOs.
Children's implicit recall of junk food, alcohol and gambling sponsorship in Australian sport.
Bestman, Amy; Thomas, Samantha L; Randle, Melanie; Thomas, Stuart D M
2015-10-05
In Australia, sport is saturated by the promotion of junk food, alcohol and gambling products. This is particularly evident on player jerseys. The effect of this advertising on children, who are exposed to these messages while watching sport, has not been thoroughly investigated. The aim of this research study was to investigate: (1) the extent to which children implicitly recalled shirt sponsors with the correct sporting team; (2) whether children associated some types of sponsors with certain sporting codes more than others; and (3) whether age of the children influenced the correct recall of sponsoring brands and teams. This experimental study conducted in New South Wales, Australia used projective techniques to measure the implicit recall of team sponsorship relationships of 85 children aged 5-12 years. Participants were asked to arrange two sets of magnets - one which contained sporting teams and one which contained brand logos - in the manner deemed most appropriate by them. Children were not given any prompts relating to sporting sponsorship relationships. Three quarters (77 %) of the children were able to identify at least one correct shirt sponsor. Children associated alcohol and gambling brands more highly with the more popular sporting code, the National Rugby League compared to the Australian Football League sporting code. Results showed that age had an effect on number of shirt sponsors correctly recalled with 9-12 year olds being significantly more likely than 5-8 year olds to correctly identify team sponsors. Given children's ability to implicitly recall shirt sponsors in a sporting context, Australian sporting codes should examine their current sponsorship relationships to reduce the number of unhealthy commodity shirt sponsors. While there is some regulation that protects children from the marketing of unhealthy commodity products, these findings suggest that children are still exposed to and recall these sponsorship relationships. Results suggest that the promotion of unhealthy commodity products during sporting matches is contributing to increased awareness amongst children of unhealthy commodity brands. Further investigation is required to examine the extent and impact of marketing initiatives during televised sporting matches on children.
Consumer Perceptions of Sponsors of Disease Awareness Advertising
ERIC Educational Resources Information Center
Hall, Danika V.; Jones, Sandra C.; Iverson, Donald C.
2011-01-01
Purpose: In many countries there is emerging concern regarding alliances between the pharmaceutical industry and health non-profit organizations (NPOs), and the increase of co-sponsored marketing activities such as disease awareness advertising. The current study aims to explore Australian women's perceptions of disease awareness advertising with…
Terms, Trends, and Insights: PV Project Finance in the United States, 2017
DOE Office of Scientific and Technical Information (OSTI.GOV)
Feldman, David J; Schwabe, Paul D
This brief is a compilation of data points and market insights that reflect the state of the project finance market for solar photovoltaic (PV) assets in the United States as of the third quarter of 2017. This information can generally be used as a simplified benchmark of the costs associated with securing financing for solar PV as well as the cost of the financing itself (i.e., the cost of capital). This work represents the second DOE sponsored effort to benchmark financing costs across the residential, commercial, and utility-scale PV markets, as part of its larger effort to benchmark the componentsmore » of PV system costs.« less
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-06
... 524 [Docket No. FDA-2012-N-0002] New Animal Drugs; Change of Sponsor; Change of Sponsor Address.... ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations to reflect a change of sponsor for two new animal drug applications (NADAs) from Janssen...
Sponsorship, ambushing, and counter-strategy: effects upon memory for sponsor and event.
Humphreys, Michael S; Cornwell, T Bettina; McAlister, Anna R; Kelly, Sarah J; Quinn, Emerald A; Murray, Krista L
2010-03-01
Corporate sponsorship of sports, causes, and the arts has become a mainstream communications tool worldwide. The unique marketing opportunities associated with major events also attract nonsponsoring companies seeking to form associations with the event (ambushing). There are strategies available to brands and events which have been ambushed; however, there is only limited information about the effects of those strategies on attainment of sponsorship objectives. In Experiment 1, university staff and students participated by studying paragraphs linking a sponsor to a novel event. Relative to each sponsor-event pair, they then studied one of three different messages about a competitor. Results find a message which linked the competitor and the event increased competitor recall given the event as a cue and event recall given the competitor as a cue. These effects were moderated if there was information about the competitor not being the sponsor. In Experiment 2 ambushing and counter-ambushing information was presented over 2 days. Both types of messages increased competitor recall given the event as a cue and event recall given the competitor as a cue. In addition, "not sponsor" information was not always used even when it should have been recallable. The results can be explained if participants are using three cues: a specific cue such as a brand name, a contextual cue, and a category cue, such as the concept of an event. Findings suggest to sponsoring firms and event properties that counter-ambushing communications may have the unintended effect of strengthening an ambusher-event relationship in memory.
The evolving role and care management approaches of safety-net Medicaid managed care plans.
Gusmano, Michael K; Sparer, Michael S; Brown, Lawrence D; Rowe, Catherine; Gray, Bradford
2002-12-01
This article provides new empirical data about the viability and the care management activities of Medicaid managed-care plans sponsored by provider organizations that serve Medicaid and other low-income populations. Using survey and case study methods, we studied these "safety-net" health plans in 1998 and 2000. Although the number of safety-net plans declined over this period, the surviving plans were larger and enjoying greater financial success than the plans we surveyed in 1998. We also found that, based on a partnership with providers, safety-net plans are moving toward more sophisticated efforts to manage the care of their enrollees. Our study suggests that, with supportive state policies, safety-net plans are capable of remaining viable. Contracting with safety-net plans may not be an efficient mechanism for enabling Medicaid recipients to "enter the mainstream of American health care," but it may provide states with an effective way to manage and coordinate the care of Medicaid recipients, while helping to maintain the health care safety-net for the uninsured.
Small transport aircraft technology propeller study
NASA Technical Reports Server (NTRS)
Black, B. M.; Magliozzi, B.; Rohrbach, C.
1983-01-01
A study to define potential benefits of advanced technology propeller for 1985-1990 STAT commuter airplanes was completed. Two baselines, a Convair, 30 passenger, 0.47 Mach number airplane and a Lockheed, 50 passenger, 0.70 Mach number airplane, were selected from NASA-Ames sponsored airframe contracts. Parametric performance, noise level, weight and cost trends for propellers with varying number of blades, activity factor, camber and diameter incorporating blade sweep, tip proplets, advanced composite materials, advanced airfoils, advanced prevision synchrophasing and counter-rotation are presented. The resulting DOC, fuel burned, empty weight and acquisition cost benefits are presented for resizings of the two baseline airplanes. Six-bladed propeller having advanced composite blades, advanced airfoils, tip proplets and advanced prevision synchrophasers provided the maximum DOC improvements for both airplanes. DOC and fuel burned were reduced by 8.3% and 17.0% respectively for the Convair airplane and by 24.9% and 41.2% respectively for the Lockheed airplane. The larger reductions arose from a baseline definition with very heavy fuselage acoustic treatment. An alternate baseline, with a cabin noise 13dB in excess of the objective, was also studied.
17 CFR 229.1104 - (Item 1104) Sponsors.
Code of Federal Regulations, 2010 CFR
2010-04-01
... describe the sponsor's form of organization. (b) Describe the general character of the sponsor's business... regarding the size, composition and growth of the sponsor's portfolio of assets of the type to be...
Abdus, Salam; Hudson, Julie; Hill, Steven C; Selden, Thomas M
2014-08-01
Both Medicaid and the Children's Health Insurance Program (CHIP), which are run by the states and funded by federal and state dollars, offer health insurance coverage for low-income children. Thirty-three states charged premiums for children at some income ranges in CHIP or Medicaid in 2013. Using data from the 1999-2010 Medical Expenditure Panel Surveys, we show that the relationship between premiums and coverage varies considerably by income level and by parental access to employer-sponsored insurance. Among children with family incomes above 150 percent of the federal poverty level, a $10 increase in monthly premiums is associated with a 1.6-percentage-point reduction in Medicaid or CHIP coverage. In this income range, the increase in uninsurance may be higher among those children whose parents lack an offer of employer-sponsored insurance than among those whose parents have such an offer. Among children with family incomes of 101-150 percent of poverty, a $10 increase in monthly premiums is associated with a 6.7-percentage-point reduction in Medicaid or CHIP coverage and a 3.3-percentage-point increase in uninsurance. In this income range, the increase in uninsurance is even larger among children whose parents lack offers of employer coverage. Project HOPE—The People-to-People Health Foundation, Inc.
The Tax Exclusion for Employer-Sponsored Insurance Is Not Regressive-But What Is It?
White, Joseph
2017-08-01
Conventional wisdom says that the tax exclusion for employer-sponsored health insurance (ESI) is "regressive and therefore unfair." Yet, by the standard definition of regressive tax policy, the conventional view is almost certainly false. It confuses the absolute size of the tax exclusion with its proportional effect on income. The error results from paying attention only to the marginal tax rate applied to ESI benefits as a portion of income and ignoring the fact that benefits are normally a much larger share of income for people with lower wages. This article explains the difference and then considers other distributional effects of ESI. It suggests that ESI-for those who receive it-further redistributes toward those with lesser means or greater need. The most evident effect is by need, favoring employees with families over those without. Yet there is good reason to believe there is also a redistribution by income, with the package of wages plus benefits being less unequal than wages alone would be. Therefore reformers should be much more careful before criticizing either ESI or its subsidy through the tax code as "unfair," especially as the likelihood of enacting something better in the United States seems quite low. Copyright © 2017 by Duke University Press.
[Clinical safety data management in company non-sponsored trials].
Saito, Akiko; Sakai, Junko; Kurihara, Masaaki; Kami, Masahiro; Kanda, Yoshinobu; Mori, Shin-ichiro; Takaue, Yoichi; Ohashi, Yasuo
2003-09-01
There is currently no harmonized way in Japan to manage safety data which are obtained during clinical trials supported by Government funds. There are two types of clinical trials, 'sponsored trials(sponsored by industrial companies)' and 'non-sponsored trials(funded by the Government, etc.)'. The Japanese Ministry of Health and Welfare has issued many of pharmaceutical laws(GCP, GPMSP etc.) for the regulation of sponsored trials, while none has ever established for non-sponsored trials, thus leaving the most important quality control/assurance unregulated. In this manuscript we discuss that the simple application of pharmaceutical laws to government-sponsored trials can not be a proper answer because of the different nature of the two types of trials.
Undergraduates with Employer-Sponsored Aid: Comparing Group Differences
ERIC Educational Resources Information Center
Faulk, Dagney G.; Wang, Zhenlei
2014-01-01
Tuition assistance offered by employers is an understudied area of financial aid research. The purpose of this study is to compare the demographic, socioeconomic, academic and financial aid characteristics of college students who receive employer-sponsored financial aid with students who receive traditional financial aid (institutional, state, or…
ERIC Educational Resources Information Center
Siemens, Jennifer Christie; Kopp, Steven W.
2006-01-01
Universities have become sensitized to the potential for students' illegal downloading of copyrighted materials. Education has been advocated as one way to curb downloading of copyrighted digital content. This study investigates the effectiveness of a university-sponsored computing ethics education program. The program positively influenced…
26 CFR 1.509(a)-4 - Supporting organizations.
Code of Federal Regulations, 2013 CFR
2013-04-01
... particular field of social science. The sponsoring organizations organized Y Council as a means of pooling... studies and formal discussions in various fields of social science. Under Y Council's by-laws, each of the... evaluation in the social sciences and sponsors or arranges conferences, seminars, and similar programs for...
26 CFR 1.509(a)-4 - Supporting organizations.
Code of Federal Regulations, 2014 CFR
2014-04-01
... particular field of social science. The sponsoring organizations organized Y Council as a means of pooling... studies and formal discussions in various fields of social science. Under Y Council's by-laws, each of the... evaluation in the social sciences and sponsors or arranges conferences, seminars, and similar programs for...
ERIC Educational Resources Information Center
Hamilton, Zoya
2012-01-01
This research study examined support to sponsored programs administrators (SPAs, or research administrators) at baccalaureate universities from their chief executives. Support to SPAs strengthens the shared purpose of the university, enabling SPAs to serve as effective organizational representatives in business transactions pertaining to grants…
The Integrative Studies of Genetic and Environmental Factors in Systemic Sclerosis
2009-05-01
University of Texas Health Science Center Houston, Texas 77030-3900 REPORT DATE...May 2009 TYPE OF REPORT: Annual PREPARED FOR: U.S. Army Medical Research and Materiel Command... Texas Health Science Center Houston, Texas 77030-3900 9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR
Linking Training Course Support to Fleet Platforms: An Equipment-Based Approach.
1981-01-01
6408 ZDB:ZT-2154T CAT:AP NEC 1: NEC 2: REQUIREMENT SPONSOR:OP-120E RESOURCE SPONSOR:OP-Ol COURSE TITLE - BE/E-ET-COMM 4YO ACTIVITY ADDRESS...CAT:AP NEC 1: NEC 2: REQUIREMENT SPONSOR:OP-120E RESOURCE SPONSOR:OP-01 COURSE TITLE - BE/E-ET-RAD 4YO ACTIVITY ADDRESS- SERVSCOLCOM SAN DIEGO FIND...0454S CAT:AP NEC 1: NEC 2: REQUIREMENT SPONSOR:OP-120E RESOURCE SPONSOR:OP-O1 COURSE TITLE - BE/E-ET-COMM 4YO ACTIVITY ADDRESS- SERVSCOLCOM GREAT LAKES
2016-05-26
Four Leaders, Three Cease-Fires, and Two Summits.” Center for Strategic and International Studies , October 23, 2015. Accessed April 17, 2016. http...United States A Monograph By MAJ Valerică-Iulian Sărățeanu Romanian Army School of Advanced Military Studies United States Army Command...SPONSOR/MONITOR’S ACRONYM(S) School of Advanced Military Studies , Advanced Military Studies Program 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 12
Can the ministry collaborate to form the "next generation" of sponsors?
Stanley, Teresa
2007-01-01
In looking to the future of sponsored ministry of Catholic institutions, the formation of future sponsors--both religious and lay alike--is an important issue. As this ministry continues to evolve, and sponsoring groups determine how best to prepare new sponsors, might it not be time to think about how to pool the ministry's collective wisdom on formation? Sponsors act not only in the name of the health care institution (or other ministry) but on behalf of the faith community engaged in continuing the compassionate healing ministry of Jesus. In Catholic ministry, and particularly health care ministry, sponsors carry out their responsibilities through a multiplicity of organizational relationships. Just as structures differ, so too do criteria that guide who will be called to join a sponsoring group. There are several core elements that are incorporated in the majority of sponsor competency sets. Elements identified by a committee of ministry members, and reviewed by hundreds of sponsors and other ministry leaders are: mission oriented, animated, theologically grounded, collaborative, church related, and accountable. If one is looking at the potential for convening dialogues about possible areas of collaboration in formation, these core elements, with examples of how they are lived out, may offer an outline of areas new sponsors might need to learn more about for their personal and professional development. Our Catholic health ministry depends on leaders who can create and steward organizational cultures that incarnate Jesus' healing. The possibilities for collaboration in the formation of future sponsors are endless, but there are challenges. If you are a member of a sponsor body/council/corporate member in Catholic health care, and are interested in nominating potential persons to take part in a representative group that would discuss possibilities for collaboration in sponsor formation, please go to www.chausa.org/sponsorformation and complete all sections of the nomination form.
ERIC Educational Resources Information Center
Northcraft, Terry G.
2017-01-01
This qualitative study examined the effect the level of project management maturity a banking IT project sponsor has on project success. Project management maturity is gauged by the amount of modern project management training, knowledge and organizational skills an individual or organization has and applies to their project lifecycle experiences.…
The frequency of company-sponsored alcohol brand-related sites on Facebook™-2012.
Nhean, Siphannay; Nyborn, Justin; Hinchey, Danielle; Valerio, Heather; Kinzel, Kathryn; Siegel, Michael; Jernigan, David H
2014-06-01
This research provides an estimate of the frequency of company-sponsored alcohol brand-related sites on Facebook™. We conducted a systematic overview of the extent of alcohol brand-related sites on Facebook™ in 2012. We conducted a 2012 Facebook™ search for sites specifically related to 898 alcohol brands across 16 different alcoholic beverage types. Descriptive statistics were produced using Microsoft SQL Server. We identified 1,017 company-sponsored alcohol-brand related sites on Facebook™. Our study advances previous literature by providing a systematic overview of the extent of alcohol brand sites on Facebook™.
Stevens, Edward B; Jason, Leonard A
Alcoholics Anonymous recommends members to have sponsors, especially those early in their recovery, yet little research has been done on the qualities of an effective sponsor. 245 adults (117 females, 128 males) currently in substance use disorder recovery participated. 231 of these individuals had experience as a sponsor, sponsee or both (109 had experience as a sponsor). Qualitative results suggest effective sponsors are currently engaged in the program on a personal level, are trustworthy, and are available although a wide variety of attributes were cited. In a choice and ranking exercise, 12- step engagement and qualities of character were also most often ranked highly. No significant differences were found between genders or sponsor/sponsee roles. Implications based on breadth of responses and dominant themes are discussed as well as the need for further research on sponsor/sponsee characteristics, satisfaction, and recovery outcomes.
Biomarker Discovery and Mechanistic Studies of Prostate Cancer Using Targeted Proteomic Approaches
2010-07-01
1-0431 TITLE: Biomarker Discovery and Mechanistic Studies of Prostate Cancer Using Targeted Proteomic Approaches PRINCIPAL INVESTIGATOR...June 2010 4. TITLE AND SUBTITLE Biomarker Discovery and Mechanistic Studies of Prostate Cancer Using Targeted Proteomic 5a. CONTRACT NUMBER...1-0430; W81XWH-08-1-0431; Grant sponsor: NIH/NCRR COBRE Grant; Grant number: 1P20RR020171; Grant sponsor: NIH/NIDDK Grant; Grant number: R01DK053525
Adapting Short of Doctrine: US Military Counterinsurgency in Iraq March 2004-December 2006
2017-05-25
by MAJ Darrell E. Fawley US Army School of Advanced Military Studies United States Army Command and General Staff College Fort Leavenworth, Kansas...AGENCY NAME(S) AND ADDRESS(ES) Advanced Military Studies Program 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION...AVAILABILITY STATEMENT Approved for Public Release; Distribution is Unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT This study argues that officers
Health Risk Reduction Programs in Employer-Sponsored Health Plans: Part I—Efficacy
Rothstein, Mark A.; Harrell, Heather L.
2011-01-01
Objective We sought to determine whether workplace health risk reduction programs (HRRPs) using health risk assessments (HRAs), individually focused risk reduction, and financial incentives succeeded in improving employee health and reducing employer health benefit costs. Methods We reviewed the proprietary HRA available to us and conducted a literature review to determine the efficacy of HRRPs using HRAs, individualized employee interventions, and financial incentives for employee participation. Results There is some evidence that HRRPs in employer-sponsored programs improve measures of employee health, but the results of these studies are somewhat equivocal. Conclusion Employer-sponsored HRRPs may have some benefits, but problems in plan design and in the studies assessing their efficacy complicate drawing conclusions. PMID:19625972
42 CFR 423.510 - Termination of contract by the Part D sponsor.
Code of Federal Regulations, 2010 CFR
2010-10-01
... to the Part D plan sponsor ends as of the first day of the month after the last month for which the... 42 Public Health 3 2010-10-01 2010-10-01 false Termination of contract by the Part D sponsor. 423... Procedures and Contracts with Part D plan sponsors § 423.510 Termination of contract by the Part D sponsor...
The Complex Dynamics of Sponsored Search Markets
NASA Astrophysics Data System (ADS)
Robu, Valentin; La Poutré, Han; Bohte, Sander
This paper provides a comprehensive study of the structure and dynamics of online advertising markets, mostly based on techniques from the emergent discipline of complex systems analysis. First, we look at how the display rank of a URL link influences its click frequency, for both sponsored search and organic search. Second, we study the market structure that emerges from these queries, especially the market share distribution of different advertisers. We show that the sponsored search market is highly concentrated, with less than 5% of all advertisers receiving over 2/3 of the clicks in the market. Furthermore, we show that both the number of ad impressions and the number of clicks follow power law distributions of approximately the same coefficient. However, we find this result does not hold when studying the same distribution of clicks per rank position, which shows considerable variance, most likely due to the way advertisers divide their budget on different keywords. Finally, we turn our attention to how such sponsored search data could be used to provide decision support tools for bidding for combinations of keywords. We provide a method to visualize keywords of interest in graphical form, as well as a method to partition these graphs to obtain desirable subsets of search terms.
A review of NASA-sponsored technology assessment projects
NASA Technical Reports Server (NTRS)
Mascy, A. C.; Alexander, A. D., III; Wood, R. D.
1978-01-01
Recent technology assessment studies sponsored by NASA are reviewed, and a summary of the technical results as well as a critique of the methodologies are presented. The reviews include Assessment of Lighter-Than-Air Technology, Technology Assessment of Portable Energy RDT&P, Technology Assessment of Future Intercity Passenger Transportation Systems, and Technology Assessment of Space Disposal of Radioactive Nuclear Waste. The use of workshops has been introduced as a unique element of some of these assessments. Also included in this report is a brief synopsis of a method of quantifying opinions obtained through such group interactions. Representative of the current technology assessments, these studies cover a broad range of socio-political factors and issues in greater depth than previously considered in NASA sponsored studies. In addition to the lessons learned through the conduct of these studies, a few suggestions for improving the effectiveness of future technology assessments are provided.
Beran, Roy G
2004-01-01
Most multi-centre trials are both financed and sponsored by the pharmaceutical company involved. What follows will map the path adopted for an investigator initiated and sponsored study for a new indication of an established medication. The chief investigators of a company-sponsored, investigator-initiated, multi-centre, placebo-controlled study of an established medication, Pharmaceutical Benefit Scheme (PBS) listed for treatment of one condition but trialled in the management of another condition (trial of off-label use), were approached to submit a protocol to repeat the type of study with a different compound. The new study would test a different agent, also PBS listed, for the same condition as in the initial study and with the same off-licence application. The company would finance the study, provide the medication and matched placebo but only review the investigator-initiated protocol which would be sponsored by the principal investigator. This required the investigator to implement the trial, as would normally be done by the pharmaceutical company, yet also act as its principal investigator. The principal investigator, with colleagues and a Clinical Research Organisation (CRO), developed a protocol, adapted for the new agent, and submitted it for approval. Upon acceptance a contract was negotiated with the pharmaceutical company which had to overcome jurisdictional conflicts between common law and civil law legal systems. A CRO was contracted to undertake administrative functions which dictated special contractual agreements to overcome possible conflicts of interest for a sponsor/investigator to protect patient interests. There was need to find indemnification insurance with jurisdictional problems, co-investigators, ethics committee approvals and finance management as just some of the difficulties encountered. The paper will outline how these obstacles were overcome and how ethical and legal issues were respected through compromise. The ethical and legal obligations were addressed in a fashion which allowed the conduct of a trial adopting a proven methodology but novel infrastructure such that it was a totally independent study with regards conduct and reporting of final data, irrespective of the results being either positive or negative. This may represent a more acceptable way to ensure that future clinical trials are devoid of undue influence from the pharmaceutical industry which may still fund the study.
Perceived Effects of Earning a Reading Endorsement in a Single-District Sponsored Reading Cohort
ERIC Educational Resources Information Center
Atwood, Bonny L.
2011-01-01
This grounded theory study examined the perceived effects of a cohort of seven secondary-level teachers earning a reading endorsement in a single-district sponsored professional development program. The researcher collected data through semi-structured personal interviews with the teachers, their principal, and the director of special services for…
Barriers to Employer Sponsored Training in Ontario. Results of a Field Study.
ERIC Educational Resources Information Center
Harvey, Edward B.
Results of a field survey of Canadian companies, trade unions, employer associations, educational establishments, and government agencies regarding the extent and possibilities of employer-sponsored training for workers are compiled in this report. Concentrating on the forty-nine companies in the survey sample, with collateral data from the…
Use and Misuse of Industry Sponsored Materials.
ERIC Educational Resources Information Center
DuVall, Charles R.; Krepel, Wayne J.
A review of educational research reveals that free and inexpensive materials are used today to a much greater extent than they had been in the past. Two studies, sponsored by the American Iron and Steel Institute, are evidence of the producer's interest in determining the strengths and weaknesses of the materials being sent into classrooms and…
The Perceived Influence of Industry-Sponsored Credentials in the Information Technology Industry.
ERIC Educational Resources Information Center
Bartlett, Kenneth R.
A study investigated the influence of information technology (IT)-industry-sponsored credentials from both organizational and individual perspectives. A senior-level human resource (HR) executive from each of 33 organizations with 500 or more employees completed a paper-and-pencil questionnaire (response rate=66% of the 50 organizations comprising…
ERIC Educational Resources Information Center
Tran, Henry; Smith, Douglas
2017-01-01
Studies of community college finance often focus on revenue sources from the state and local government, private foundations, and tuition. While these resources are important, an often-neglected source of revenue is employer-sponsored educational assistance benefits for students. Given the dearth of literature on the benefits of this funding…
A Commentary on Literacy Narratives as Sponsors of Literacy
ERIC Educational Resources Information Center
Brandt, Deborah
2015-01-01
This brief commentary first clarifies Brandt's concept of sponsors of literacy in light of the way the concept has been taken up in writing studies. Then it treats Brandt's methods for handling accounts of literacy learning in comparison with other ways of analyzing biographical material. Finally it takes up Lawrence's argument about literacy…
Ethics in clinical drug trial research in private practice.
Beran, R G; Beran, M E
2006-09-01
Private clinics and clinicians have been involved in clinical drug trials for approximately two decades. This paper reviews the ethical consideration inherent in this process. Involvement of a single community based, private, Australian neurological clinic in the conduct of trials was audited. Changes in ethical considerations were analysed. The clinic previously audited its clinical trial involvement, starting with pharmaceutical company orchestrated trials. These were vetted by hospital based ethics committees (ECs) which then refused to review private research. A private EC accommodating NH & MRC standards was formed to assess private research. Indemnity concerns forced return to institutional ECs with government guaranteed indemnification. Trials evolved to investigator initiated, company sponsored studies thence a company asking the clinic to devise, sponsor and manage a trial. The latter relegated trial co-ordination to the clinic which would control publication thereby creating new ethical standards. Private practice trial involvement evolved from reluctant inclusion to a pivotal role in privately sponsored studies. Access to ECs is government endorsed and publication is independent for investigator-sponsored trials. There has been modification of standard operating procedures and enhanced ethical standards.
van Lent, Marlies; Rongen, Gerard A; Out, Henk J
2014-12-10
Submission of study protocols to research ethics committees (RECs) constitutes one of the earliest stages at which planned trials are documented in detail. Previous studies have investigated the amendments requested from researchers by RECs, but the type of issues raised during REC review have not been compared by sponsor type. The objective of this study was to identify recurring shortcomings in protocols of drug trials based on REC comments and to assess whether these were more common among industry-sponsored or non-industry trials. Retrospective analysis of 226 protocols of drug trials approved in 2010-2011 by three RECs affiliated to academic medical centres in The Netherlands. For each protocol, information on sponsorship, number of participating centres, participating countries, study phase, registration status of the study drug, and type and number of subjects was retrieved. REC comments were extracted from decision letters sent to investigators after review and were classified using a predefined checklist that was based on legislation and guidelines on clinical drug research and previous literature. Most protocols received comments regarding participant information and consent forms (n = 182, 80.5%), methodology and statistical analyses (n = 160, 70.8%), and supporting documentation, including trial agreements and certificates of insurance (n = 154, 68.1%). Of the submitted protocols, 122 (54.0%) were non-industry and 104 (46.0%) were industry-sponsored trials. Non-industry trials more often received comments on subject selection (n = 44, 36.1%) than industry-sponsored trials (n = 18, 17.3%; RR, 1.58; 95% CI, 1.01 to 2.47), and on methodology and statistical analyses (n = 95, 77.9% versus n = 65, 62.5%, respectively; RR, 1.18; 95% CI, 1.01 to 1.37). Non-industry trials less often received comments on supporting documentation (n = 72, 59.0%) than industry-sponsored trials (n = 82, 78.8%; RR, 0.83; 95% CI, 0.72 to 0.95). RECs identified important ethical and methodological shortcomings in protocols of both industry-sponsored and non-industry drug trials. Investigators, especially of non-industry trials, should better prepare their research protocols in order to facilitate the ethical review process.
United States Navy Humanitarian Assistance and Disaster Relief (HADR) Costs: A Preliminary Study
2015-08-26
SPONSORED REPORT SERIES United States Navy Humanitarian Assistance and Disaster Relief (HADR) Costs: A Preliminary Study 26 August 2015 Aruna Apte...Graduate School of Business & Public Policy at the Naval Postgraduate School. To request defense acquisition research, to become a research sponsor...inspiration to us, Cullen M. Greenfield, Cameron A . Ingram, Stephen A . Ures, Dana M. Herbert, James A . Prosser, Rachele A . Wharton, Alexander Kaczur
ERIC Educational Resources Information Center
Torrance, E. Paul; And Others
This task group report is one of a series prepared by eminent psychologists who have served as consultants in the U.S. Office of Education-sponsored grant study to conduct a Critical Appraisal of the Personality-Emotion-motivation Domain. In order to achieve the goal of identifying important problems and areas for new research and methodological…
2016-04-14
study dynamic events such as melting, evaporation, crystallization, dissolution, self-assembly, membrane disruption, sample movement tracking. To... polymeric hairy nanopraticle, suprastructures REPORT DOCUMENTATION PAGE 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 10. SPONSOR/MONITOR’S ACRONYM(S...the AFM will permit us to study dynamic events such as melting, evaporation, crystallization, dissolution, self-assembly, membrane disruption, sample
Trust as a Currency: The Role of Relationships in the Human Domain
2014-05-22
Army School of Advanced Military Studies United States Army Command and General Staff College Fort Leavenworth, Kansas 2014-01...School of Advanced Military Studies 201 Reynolds Ave. Fort Leavenworth, KS 66027-2301 8. PERFORMING ORG REPORT NUMBER 9. SPONSORING...MONITORING AGENCY NAME(S) AND ADDRESS(ES) U.S. Army Command and General Staff College ATTN: ATZL-SWD-GD Fort Leavenworth, KS 66027-2301 10. SPONSOR
45 CFR 1226.12 - Sponsor employees.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 45 Public Welfare 4 2010-10-01 2010-10-01 false Sponsor employees. 1226.12 Section 1226.12 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE PROHIBITIONS ON ELECTORAL AND LOBBYING ACTIVITIES Sponsor Employee Activities § 1226.12 Sponsor employees...
Recent methodological advances in male hormonal contraception
Liu, Peter Y.; Swerdloff, Ronald S.; Wang, Christina
2010-01-01
Landmark WHO-sponsored trials showed decades ago that male hormonal contraception (MHC) is an effective male-directed contraceptive approach. Considerable progress has been made particularly in the last 5 years, establishing for the first time the reversibility of MHC and its short-term safety. Methodological advances in recent years include: the pooling of information and individual-level integrated analysis; the first-time use of centralized semen analysis and fluorescence to detect low sperm concentrations; the establishment of sperm quality reference ranges in fertile men; the measurement of blood steroid concentrations by gas or chromatography/mass spectrometry; and the inclusion of placebo groups to delineate clearly possible adverse effects of androgens and progestins in men. We report integrated analyses of factors that are important in predicting suppression and recovery of spermatogenesis after MHC clinical trials for the past 15 years. These are the best data available and will provide guidance and reassurance for the larger scale Phase III specific regimen efficacy studies that will be required to bring MHC to the population (market). PMID:20933121
Code of Federal Regulations, 2010 CFR
2010-10-01
... sponsor or by CMS before notice of the reconsidered determination is made. (6) Decision of the informal written reconsideration. CMS informs the sponsor of the decision orally or through electronic mail. CMS sends a written decision to the sponsor on the sponsor's request. (7) Effect of CMS informal written...
48 CFR 235.017-1 - Sponsoring agreements.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Sponsoring agreements. 235.017-1 Section 235.017-1 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... Sponsoring agreements. (c)(4) DoD-sponsoring FFRDCs that function primarily as research laboratories (C3I...
31 CFR 1030.210 - Anti-money laundering programs for housing government sponsored enterprises.
Code of Federal Regulations, 2014 CFR
2014-07-01
... activities. The program must be approved by senior management. A housing government sponsored enterprise... housing government sponsored enterprises. 1030.210 Section 1030.210 Money and Finance: Treasury... TREASURY RULES FOR HOUSING GOVERNMENT SPONSORED ENTERPRISES Programs § 1030.210 Anti-money laundering...
Assessment of government tribology programs
DOE Office of Scientific and Technical Information (OSTI.GOV)
Peterson, M.B.; Levinson, T.M.
1985-09-01
An assessment has been made to determine current tribology research and development work sponsored or conducted by the government. Data base surveys and discussions were conducted to isolate current projects sponsored primarily by 21 different government organizations. These projects were classified by subject, objective, energy relevance, type of research, phenomenon being investigated, variables being studied, type of motion, materials and application. An abstract of each project was prepared which included the classification, sponsor, performing organization and a project description. It was found that current work is primarily materials oriented to meet military requirements. Other than the high temperature programs verymore » few of the tribology projects accomplish energy related objectives.« less
Thoracic aortic aneurysms and dissections: endovascular treatment.
Baril, Donald T; Cho, Jae S; Chaer, Rabih A; Makaroun, Michel S
2010-01-01
The treatment of thoracic aortic disease has changed radically with the advances made in endovascular therapy since the concept of thoracic endovascular aortic repair was first described 15 years ago. Currently, there is a diverse array of endografts that are commercially available to treat the thoracic aorta. Multiple studies, including industry-sponsored and single-institution reports, have demonstrated excellent outcomes of thoracic endovascular aortic repair for the treatment of thoracic aortic aneurysms, with less reported perioperative morbidity and mortality in comparison with conventional open repair. Additionally, similar outcomes have been demonstrated for the treatment of type B dissections. However, the technology remains relatively novel, and larger studies with longer term outcomes are necessary to more fully evaluate the role of endovascular therapy for the treatment of thoracic aortic disease. This review examines the currently available thoracic endografts, preoperative planning for thoracic endovascular aortic repair, and outcomes of thoracic endovascular aortic repair for the treatment of both thoracic aortic aneurysms and type B aortic dissections. Mt Sinai J Med 77:256-269, 2010. (c) 2010 Mount Sinai School of Medicine.
45 CFR 149.600 - Sponsor's duty to report data inaccuracies.
Code of Federal Regulations, 2014 CFR
2014-10-01
... HEALTH CARE ACCESS REQUIREMENTS FOR THE EARLY RETIREE REINSURANCE PROGRAM Disclosure of Data Inaccuracies § 149.600 Sponsor's duty to report data inaccuracies. A sponsor is required to disclose any data... 45 Public Welfare 1 2014-10-01 2014-10-01 false Sponsor's duty to report data inaccuracies. 149...
45 CFR 149.600 - Sponsor's duty to report data inaccuracies.
Code of Federal Regulations, 2012 CFR
2012-10-01
... HEALTH CARE ACCESS REQUIREMENTS FOR THE EARLY RETIREE REINSURANCE PROGRAM Disclosure of Data Inaccuracies § 149.600 Sponsor's duty to report data inaccuracies. A sponsor is required to disclose any data... 45 Public Welfare 1 2012-10-01 2012-10-01 false Sponsor's duty to report data inaccuracies. 149...
8 CFR 213a.4 - Actions for reimbursement, public notice, and congressional reports.
Code of Federal Regulations, 2010 CFR
2010-01-01
... SECURITY IMMIGRATION REGULATIONS AFFIDAVITS OF SUPPORT ON BEHALF OF IMMIGRANTS § 213a.4 Actions for... immigrant wants to seek reimbursement from a sponsor, household member, or joint sponsor, the program... commenced (this is the date the sponsored immigrant became a permanent resident), the sponsored immigrant's...
42 CFR 423.401 - General requirements for PDP sponsors.
Code of Federal Regulations, 2010 CFR
2010-10-01
... with State Law and Preemption by Federal Law § 423.401 General requirements for PDP sponsors. (a... sponsor is organized and licensed under State law as a risk bearing entity eligible to offer health... otherwise licensed, the sponsor obtains certification from the State that the organization meets a level of...
Pensions: worker coverage and retirement income, 1984.
Nelson, C T
1987-09-01
The 4th wave topical module to the 1984 panel of the Survey of Income and Program Participation, conducted September through December of 1984, contained supplemental questions on both pension eligibility of the working population and on characteristics of persons receiving retirement income. This report presents findings based on these supplemental questions. The prevalence of pension coverage among different segments of the population, the reliance on employee-directed retirement plans, and differences in the level of economic well-being of today's retirees are some of the topics discussed in this report. Some highlights of the data follow. 1) In 1984, 52.7 million (67.1%) of wage and salary workers were covered by an employer-sponsored pension plan. 2) The pension coverage rate of workers with monthly earnings of $500 was 37.8%; the pension coverage rate of workers with monthly earnings of $2000 or more was 84.1%. 3) Employees of larger firms were far more likely to be covered by an employee-sponsored pension plan than employees of smaller firms, 4) In 1984, 16.3 million wage and salary workers contributed to Individual Retirement Accounts. The pension coverage rate of these workers was 75.8%. 5) About 6.1% of all wage and salary workers participated in employer-sponsored thrift plans, known as 401(k) plans. 6) 72.1% of workers are covered by either an employer-sponsored pension, IRA, or 401 (k) plan. 7) There were 11.5 million retirees receiving pension benefits in August 1984. Their average monthly pension income was $570. 8) 66.4% of all retirees receiving pension benefits were male; male retirees received about $670 per month, while females received $370. 9) Retirees younger than 65 received significantly more pension income than those over 65. Older retirees were much more likely to be receiving Social Security benefits in addition to their pensions. 10) 19.6% of the 11.5 million retirement pension recipients completed 4 or more years of college. Their mean pension income was $950, compared to $550 for retirees with only 4 years of high school. 11) About 1.8 million retirees, or 15.7% of all retirement pension recipients, worked during the reference month. Working retirees received average pension incomes of $730, while nonworking retirees received $540.
Quantifiable outcomes from corporate and higher education learning collaborations
NASA Astrophysics Data System (ADS)
Devine, Thomas G.
The study investigated the existence of measurable learning outcomes that emerged out of the shared strengths of collaborating sponsors. The study identified quantifiable learning outcomes that confirm corporate, academic and learner participation in learning collaborations. Each of the three hypotheses and the synergy indicator quantitatively and qualitatively confirmed learning outcomes benefiting participants. The academic-indicator quantitatively confirmed that learning outcomes attract learners to the institution. The corporate-indicator confirmed that learning outcomes include knowledge exchange and enhanced workforce talents for careers in the energy-utility industry. The learner-indicator confirmed that learning outcomes provide professional development opportunities for employment. The synergy-indicator confirmed that best learning practices in learning collaborations emanate out of the sponsors' shared strengths, and that partnerships can be elevated to strategic alliances, going beyond response to the desires of sponsors to create learner-centered cultures. The synergy-indicator confirmed the value of organizational processes that elevate sponsors' interactions to sharing strength, to create a learner-centered culture. The study's series of qualitative questions confirmed prior success factors, while verifying the hypothesis results and providing insight not available from quantitative data. The direct benefactors of the study are the energy-utility learning-collaboration participants of the study, and corporation, academic institutions, and learners of the collaboration. The indirect benefactors are the stakeholders of future learning collaborations, through improved knowledge of the existence or absence of quantifiable learning outcomes.
Proof of Concept Trade Study For Type-1 Operator Training
2005-03-15
PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Lockheed Martin,9975 Federal Drive,Colorado...Springs,CO,80921 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11...CONFIGURATION .................................................................. 20 5.1 System Architechture
Sponsorshaping: How a Teacher Used Sponsors of Literacy for Pedagogical Purposes
ERIC Educational Resources Information Center
Dippre, Ryan
2016-01-01
Historically, the actions of classroom teachers have had a massive impact on the implementation of top-down reform efforts. However, a pedagogically-friendly construct for considering this impact has been lacking in studies of teacher practice. In this article, I draw on Deborah Brandt's concept of sponsors of literacy to build a construct for…
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-18
... studies of marijuana, which were sponsored by the California Center for Medical Cannabis Research (CMCR...), every one of the 17 CMCR [California Center for Medical Cannabis Research]-sponsored pre- clinical or.... Id. (The program is also referred to as the ``Center for Medicinal Cannabis Research'' (CMCR). Tr...
ERIC Educational Resources Information Center
Lane, Peter W.; Higgins, Julian P. T.; Anagnostelis, Betsy; Anzures-Cabrera, Judith; Baker, Nigel F.; Cappelleri, Joseph C.; Haughie, Scott; Hollis, Sally; Lewis, Steff C.; Moneuse, Patrick; Whitehead, Anne
2013-01-01
Context: Meta-analyses are regularly used to inform healthcare decisions. Concerns have been expressed about the quality of meta-analyses and, in particular, about those supported by the pharmaceutical industry. Objective: The objective of this study is to compare the quality of pharmaceutical-industry-supported meta-analyses with academic…
Military Family Coping Project
2013-09-01
ORGANIZATION: Baylor University Waco , TX 76798 REPORT DATE: September 2013 TYPE OF REPORT: Annual PREPARED FOR: U.S. Army Medical...ORGANIZATION REPORT NUMBER Waco , TX 76798 9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S...CA. Dennis, Regina (Staff Writer). (2012, February 28). Baylor, Waco VA hospital studying veterans’ family stress. Waco , TX: Tribune Herald
ERIC Educational Resources Information Center
Bergen, Doris; And Others
Information is presented on a study designed to collect data on the characteristics of research/sponsored programs offices at state-assisted higher education institutions that participate in the Office of Federal Programs (OFP) of the American Association of State Colleges and Universities. Objectives were to describe the characteristics of the…
ERIC Educational Resources Information Center
Davenport, Kevin O.
2010-01-01
This study examined whether or not students that participated in a school sponsored instrumental music program had higher academic achievement and attendance than students that did not participate in a school sponsor instrumental music program. Units of measurement included standardized test scores and attendance, without taking into consideration…
2012-05-01
PREPARED FOR: U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 DISTRIBUTION...SPONSOR/MONITOR’S ACRONYM(S) U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 11. SPONSOR/MONITOR’S REPORT...Subsequent research in several laboratories indicates that BA inhibits growth of multiple tumor types including breast cancer . Studies in this
2015-10-01
Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 DISTRIBUTION STATEMENT: Approved for Public Release; Distribution Unlimited The...SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) U.S. Army Medical Resear ch and Materiel Command Fort Detrick...DDT) and Medical Device Development Tool (MDDT) programs with case study presentations and question and answer opportunities. Expert Working Groups
ERIC Educational Resources Information Center
Piasta, Shayne B.; Justice, Laura M.; O'Connell, Ann A.; Mauck, Susan A.; Weber-Mayrer, Melissa; Schachter, Rachel E.; Farley, Kristin S.; Spear, Caitlin F.
2017-01-01
The current study investigated the effectiveness of large-scale, state-sponsored language and literacy professional development (PD) intended to improve early childhood educators' knowledge, beliefs, and practices. PD was offered in a real-world context and delivered at-scale across the state, implemented by an independent contractor. Educators (n…
Magnetic Resonance Studies of Photosensitizers and Their Effect in Tumors
2004-10-01
Final 2.0060307 096 PREPARED FOR: U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 DISTRIBUTION STATEMENT: Approved for...68198-5100 9. SPONSORING I MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) U.S. Army Medical Research and Materiel Command... Research Accomplishments ......................................................... 15 Reportable Outcomes
ERIC Educational Resources Information Center
Roozen, Kevin
2012-01-01
Dominant perspectives of basic writers' self-sponsored literacies tend to overlook the important roles such activities can play in literate development. Drawn from texts, interviews, and participant-observations collected during a five-year study, this article continues the examination of the relationship between one writer's curricular and…
ERIC Educational Resources Information Center
Byrne, Donn; And Others
The task group report presented in this publication is one of a series prepared by eminent psychologists who have served as consultants in the U.S.O.E.-sponsored grant study to conduct a Critical Appraisal of the Personality-Emotions-Motivation-Domain. In order to achieve the goal of identifying important problems and areas for new research and…
ERIC Educational Resources Information Center
Gorsuch, Richard L.; And Others
The task group report presented in this publication is one of a series prepared by eminent psychologists who have served as consultants in the U.S. Office of Education-sponsored grant study to conduct a Critical Appraisal of the Personality-Emotions-Motivation Domain. In order to achieve the goal of identifying important problems and areas for new…
ERIC Educational Resources Information Center
Timlin, Kevin
2017-01-01
The purpose of this study is to determine which factors influence the achievement of program objectives for Kyrgyz Republic alumni of the U.S. governmentally sponsored UGRAD program. The UGRAD program was designed to provide university students from the former Soviet Union an opportunity to study at an institute of higher education in the United…
Lavack, A M
1999-01-01
This content analysis examines a sample of 203 alcohol-related North American TV commercials dealing with alcohol moderation and driving under the influence (DUI), in order to determine whether the type of ad sponsor has an impact on the message content. Corporate sponsors, such as breweries and distillers, are compared to nonprofit sponsors such as governments and nonprofit organizations. Findings show that ads from corporate sponsors are less likely to make mention of threats or negative consequences, and are also less likely to use fear arousal. However, DUI/alcohol moderation ads from corporate sponsors and nonprofit sponsors do not differ in the degree to which they use humor or positive approaches.
Cutter Connectivity Bandwidth Study
NASA Astrophysics Data System (ADS)
2002-10-01
The goal of this study was to determine how much bandwidth is required for cutters to meet emerging data transfer requirements. The Cutter Connectivity Business Solutions Team with guidance front the Commandant's 5 Innovation Council sponsored this study. Today, many Coast Guard administrative and business functions are being conducted via electronic means. Although our larger cutters can establish part-time connectivity using commercial satellite communications (SATCOM) while underway, there are numerous complaints regarding poor application performance. Additionally, smaller cutters do not have any standard means of underway connectivity. The R&D study shows the most important factor affecting web performance and enterprise applications onboard cutters was latency. Latency describes the time it takes the signal to reach the satellite and come back down through space. The latency due to use of higher orbit satellites is causing poor application performance and inefficient use of expensive SATCOM links. To improve performance, the CC must, (1) reduce latency by using alternate communications links such as low-earth orbit satellites, (2) tailor applications to the SATCOM link and/or (3) optimize protocols used for data communication to minimize time required by present applications to establish communications between the user and the host systems.
Perez, Raymond; Archdeacon, Patrick; Roach, Nancy; Goodwin, Robert; Jarow, Jonathan; Stuccio, Nina; Forrest, Annemarie
2017-06-01
The Food and Drug Administration's final rule on investigational new drug application safety reporting, effective from 28 March 2011, clarified the reporting requirements for serious and unexpected suspected adverse reactions occurring in clinical trials. The Clinical Trials Transformation Initiative released recommendations in 2013 to assist implementation of the final rule; however, anecdotal reports and data from a Food and Drug Administration audit indicated that a majority of reports being submitted were still uninformative and did not result in actionable changes. Clinical Trials Transformation Initiative investigated remaining barriers and potential solutions to full implementation of the final rule by polling and interviewing investigators, clinical research staff, and sponsors. In an opinion-gathering effort, two discrete online surveys designed to assess challenges and motivations related to management of expedited (7- to 15-day) investigational new drug safety reporting processes in oncology trials were developed and distributed to two populations: investigators/clinical research staff and sponsors. Data were collected for approximately 1 year. Twenty-hour-long interviews were also conducted with Clinical Trials Transformation Initiative-nominated interview participants who were considered as having extensive knowledge of and experience with the topic. Interviewees included 13 principal investigators/study managers/research team members and 7 directors/vice presidents of pharmacovigilance operations from 5 large global pharmaceutical companies. The investigative site's responses indicate that too many individual reports are still being submitted, which are time-consuming to process and provide little value for patient safety assessments or for informing actionable changes. Fewer but higher quality reports would be more useful, and the investigator and staff would benefit from sponsors'"filtering" of reports and increased sponsor communication. Sponsors replied that their greatest challenges include (1) lack of global harmonization in reporting rules, (2) determining causality, and (3) fear of regulatory repercussions. Interaction with the Food and Drug Administration has helped improve sponsors' adherence to the final rule, and sponsors would benefit from increased communication with the Food and Drug Administration and educational materials. The goal of the final rule is to minimize uninformative safety reports so that important safety signals can be captured and communicated early enough in a clinical program to make changes that help ensure patient safety. Investigative staff and sponsors acknowledge that the rule has not been fully implemented although they agree with the intention. Clinical Trials Transformation Initiative will use the results from the surveys and interviews to develop new recommendations and educational materials that will be available to sponsors to increase compliance with the final rule and facilitate discussion between sponsors, investigators, and Food and Drug Administration representatives.
Promotion of tobacco products on Facebook: policy versus practice.
Jackler, Robert K; Li, Vanessa Y; Cardiff, Ryan A L; Ramamurthi, Divya
2018-04-05
Facebook has a comprehensive set of policies intended to inhibit promotion and sales of tobacco products. Their effectiveness has yet to be studied. Leading tobacco brands (388) were identified via Nielsen and Ranker databases and 108 were found to maintain brand-sponsored Facebook pages. Key indicators of alignment with Facebook policy were evaluated. Purchase links (eg, 'shop now' button) on brand-sponsored pages were found for hookah tobaccos (41%), e-cigarettes (74%), smokeless (50%) and cigars (31%). Sales promotions (eg, discount coupons) were present in hookah tobacco (48%), e-cigarette (76%) and cigar (69%) brand-sponsored pages. While conventional cigarettes did not maintain brand-sponsored pages, they were featured in 80% of online tobacco vendors' Facebook pages. The requirement for age gating, to exclude those <18 from viewing tobacco promotion, was absent in hookah tobacco (78%), e-cigarette (62%) and cigar (21%) brand-sponsored pages and for 90% of online tobacco stores which promote leading cigarette brands (eg, Marlboro, Camel). Many of the brand-sponsored tobacco product pages had thousands of 'likes'. It is laudable that Facebook has policies intended to interdict tobacco promotion throughout its platform. Nevertheless, widespread tobacco promotion and sales were found at variance with the company's policies governing advertising, commerce, page content and under age access. Vetting could be improved by automated screening in partnership with human reviewers. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
Effect of Industry Sponsorship on Dental Restorative Trials.
Schwendicke, F; Tu, Y-K; Blunck, U; Paris, S; Göstemeyer, G
2016-01-01
Industry sponsorship was found to potentially introduce bias into clinical trials. We assessed the effects of industry sponsorship on the design, comparator choice, and findings of randomized controlled trials on dental restorative materials. A systematic review was performed via MEDLINE, CENTRAL, and EMBASE. Randomized trials on dental restorative and adhesive materials published 2005 to 2015 were included. The design of sponsored and nonsponsored trials was compared statistically (risk of bias, treatment indication, setting, transferability, sample size). Comparator choice and network geometry of sponsored and nonsponsored trials were assessed via network analysis. Material performance rankings in different trial types were estimated via Bayesian network meta-analysis. Overall, 114 studies were included (15,321 restorations in 5,232 patients). We found 21 and 41 (18% and 36%) trials being clearly or possibly industry sponsored, respectively. Trial design of sponsored and nonsponsored trials did not significantly differ for most assessed items. Sponsored trials evaluated restorations of load-bearing cavities significantly more often than nonsponsored trials, had longer follow-up periods, and showed significantly increased risk of detection bias. Regardless of sponsorship status, comparisons were mainly performed within material classes. The proportion of trials comparing against gold standard restorative or adhesive materials did not differ between trial types. If ranked for performance according to the need to re-treat (best: least re-treatments), most material combinations were ranked similarly in sponsored and nonsponsored trials. The effect of industry sponsorship on dental restorative trials seems limited. © International & American Associations for Dental Research 2015.
45 CFR 233.51 - Eligibility of sponsored aliens.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 45 Public Welfare 2 2014-10-01 2012-10-01 true Eligibility of sponsored aliens. 233.51 Section 233... CONDITIONS OF ELIGIBILITY IN FINANCIAL ASSISTANCE PROGRAMS § 233.51 Eligibility of sponsored aliens... affidavit(s) of support or similar agreement on behalf of an alien (who is not the child of the sponsor or...
45 CFR 233.51 - Eligibility of sponsored aliens.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 45 Public Welfare 2 2013-10-01 2012-10-01 true Eligibility of sponsored aliens. 233.51 Section 233... CONDITIONS OF ELIGIBILITY IN FINANCIAL ASSISTANCE PROGRAMS § 233.51 Eligibility of sponsored aliens... affidavit(s) of support or similar agreement on behalf of an alien (who is not the child of the sponsor or...
45 CFR 233.51 - Eligibility of sponsored aliens.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 45 Public Welfare 2 2011-10-01 2011-10-01 false Eligibility of sponsored aliens. 233.51 Section... CONDITIONS OF ELIGIBILITY IN FINANCIAL ASSISTANCE PROGRAMS § 233.51 Eligibility of sponsored aliens... affidavit(s) of support or similar agreement on behalf of an alien (who is not the child of the sponsor or...
45 CFR 233.51 - Eligibility of sponsored aliens.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 45 Public Welfare 2 2012-10-01 2012-10-01 false Eligibility of sponsored aliens. 233.51 Section... CONDITIONS OF ELIGIBILITY IN FINANCIAL ASSISTANCE PROGRAMS § 233.51 Eligibility of sponsored aliens... affidavit(s) of support or similar agreement on behalf of an alien (who is not the child of the sponsor or...
45 CFR 233.51 - Eligibility of sponsored aliens.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 45 Public Welfare 2 2010-10-01 2010-10-01 false Eligibility of sponsored aliens. 233.51 Section... CONDITIONS OF ELIGIBILITY IN FINANCIAL ASSISTANCE PROGRAMS § 233.51 Eligibility of sponsored aliens... affidavit(s) of support or similar agreement on behalf of an alien (who is not the child of the sponsor or...
76 FR 2807 - New Animal Drugs; Change of Sponsor; Follicle Stimulating Hormone
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-18
... [Docket No. FDA-2010-N-0002] New Animal Drugs; Change of Sponsor; Follicle Stimulating Hormone AGENCY...) is amending the animal drug regulations to reflect a change of sponsor for a new animal drug... currently listed in the animal drug regulations as a sponsor of an approved application. Accordingly, Sec...
7 CFR 654.14 - Duration of sponsor(s)' responsibility.
Code of Federal Regulations, 2010 CFR
2010-01-01
... performed by force account, division of work, or performance of work methods, the sponsor(s)' O&M responsibilities begin on the date the work or portion thereof is completed as determined by NRCS, except for completed work located on Federal lands which are subject to special-use permits. The O&M agreement shall...
Rosenberg, N; Siegel, M.
2001-01-01
OBJECTIVE—To describe the nature and extent of tobacco company sponsorship in the USA during the period 1995-99 and analyse this sponsorship in a marketing context. DESIGN—A cross-sectional study of tobacco company sponsorships identified through a customised research report from IEG Inc, and from internet web site searches. METHODS—First, a customised report was received from IEG Inc, which identified sponsorship activities for Philip Morris, RJ Reynolds, Brown & Williamson, Lorillard, and US Tobacco for the years 1997 and 1998. Second, the internet was systematically searched for tobacco industry sponsorships during the period 1995-99 by the same parent companies and their respective brands. RESULTS—During the period 1995-99, tobacco companies sponsored at least 2733 events, programmes, and organisations in the USA. Sponsorships involved all 50 states and the District of Columbia, and the minimum total funding amount of these sponsorships was $365.4 million. Tobacco corporate sponsorships involved numerous small, community based organisations, both through direct funding and through grants to larger umbrella organisations, and many of these organisations were part of the public health infrastructure. CONCLUSIONS—Tobacco corporate sponsorship serves as an important marketing tool for tobacco companies, serving both a sales promotion and public relations function. Public health practitioners need to develop better surveillance systems for monitoring tobacco sponsorship, to seek out alternative funding sources for tobacco company sponsored events and organisations, and to consider promoting a ban on tobacco sponsorship, possibly linking such regulation to the creation of alternative funding sources. Keywords: marketing; sponsorship; tobacco industry PMID:11544388
Gosselin, Sylvie J; Palate, Bernard; Parker, George A; Engelhardt, Jeffery A; Hardisty, Jerry F; McDorman, Kevin S; Tellier, Pierre A; Silverman, Lee R
2011-02-01
This article provides observations on the features of sponsor-contract research organization communication that will achieve the best quality pathology report based on our collective experience. Information on the test article and any anticipated findings should be provided, and initial slide examination should be done with knowledge of treatment group (but may be followed by blinded review of target tissues to determine no-effect levels). Only a pathologist should write or revise the pathology report or the pathology section of the overall study report. To address concerns related to undue sponsor influence, comments by sponsors should be presented as suggestions rather than directives. Adversity should be defined for each finding by the study pathologist, but the no-observed adverse effect level should not be discussed in the pathology report. Board-certified pathologists are recommended, but are not essential. Sponsors that have a particular format or report preferences should make them known well in advance. Histologic processing "to glass" of protocol-specified tissues from all dosage groups is recommended for rapid evaluation of target tissues. Telepathology is beneficial in certain situations, but it is usually more efficient for the study pathologist and reviewing pathologist to be in the same physical location to review differences of opinion and reach a consensus.
45 CFR 2553.61 - When may a sponsor serve as a volunteer station?
Code of Federal Regulations, 2012 CFR
2012-10-01
... 45 Public Welfare 4 2012-10-01 2012-10-01 false When may a sponsor serve as a volunteer station... FOR NATIONAL AND COMMUNITY SERVICE THE RETIRED AND SENIOR VOLUNTEER PROGRAM Responsibilities of a Volunteer Station § 2553.61 When may a sponsor serve as a volunteer station? The sponsor may function as a...
45 CFR 2552.61 - May a sponsor serve as a volunteer station?
Code of Federal Regulations, 2012 CFR
2012-10-01
... 45 Public Welfare 4 2012-10-01 2012-10-01 false May a sponsor serve as a volunteer station? 2552... NATIONAL AND COMMUNITY SERVICE FOSTER GRANDPARENT PROGRAM Responsibilities of a Volunteer Station § 2552.61 May a sponsor serve as a volunteer station? Yes, a sponsor may serve as a volunteer station, provided...
45 CFR 2553.61 - When may a sponsor serve as a volunteer station?
Code of Federal Regulations, 2014 CFR
2014-10-01
... 45 Public Welfare 4 2014-10-01 2014-10-01 false When may a sponsor serve as a volunteer station... FOR NATIONAL AND COMMUNITY SERVICE THE RETIRED AND SENIOR VOLUNTEER PROGRAM Responsibilities of a Volunteer Station § 2553.61 When may a sponsor serve as a volunteer station? The sponsor may function as a...
45 CFR 2551.61 - May a sponsor serve as a volunteer station?
Code of Federal Regulations, 2011 CFR
2011-10-01
... 45 Public Welfare 4 2011-10-01 2011-10-01 false May a sponsor serve as a volunteer station? 2551... NATIONAL AND COMMUNITY SERVICE SENIOR COMPANION PROGRAM Responsibilities of a Volunteer Station § 2551.61 May a sponsor serve as a volunteer station? Yes, a sponsor may serve as a volunteer station, provided...
45 CFR 2553.61 - When may a sponsor serve as a volunteer station?
Code of Federal Regulations, 2013 CFR
2013-10-01
... 45 Public Welfare 4 2013-10-01 2013-10-01 false When may a sponsor serve as a volunteer station... FOR NATIONAL AND COMMUNITY SERVICE THE RETIRED AND SENIOR VOLUNTEER PROGRAM Responsibilities of a Volunteer Station § 2553.61 When may a sponsor serve as a volunteer station? The sponsor may function as a...
45 CFR 2552.61 - May a sponsor serve as a volunteer station?
Code of Federal Regulations, 2013 CFR
2013-10-01
... 45 Public Welfare 4 2013-10-01 2013-10-01 false May a sponsor serve as a volunteer station? 2552... NATIONAL AND COMMUNITY SERVICE FOSTER GRANDPARENT PROGRAM Responsibilities of a Volunteer Station § 2552.61 May a sponsor serve as a volunteer station? Yes, a sponsor may serve as a volunteer station, provided...
45 CFR 2553.61 - When may a sponsor serve as a volunteer station?
Code of Federal Regulations, 2010 CFR
2010-10-01
... 45 Public Welfare 4 2010-10-01 2010-10-01 false When may a sponsor serve as a volunteer station... FOR NATIONAL AND COMMUNITY SERVICE THE RETIRED AND SENIOR VOLUNTEER PROGRAM Responsibilities of a Volunteer Station § 2553.61 When may a sponsor serve as a volunteer station? The sponsor may function as a...
45 CFR 2552.61 - May a sponsor serve as a volunteer station?
Code of Federal Regulations, 2014 CFR
2014-10-01
... 45 Public Welfare 4 2014-10-01 2014-10-01 false May a sponsor serve as a volunteer station? 2552... NATIONAL AND COMMUNITY SERVICE FOSTER GRANDPARENT PROGRAM Responsibilities of a Volunteer Station § 2552.61 May a sponsor serve as a volunteer station? Yes, a sponsor may serve as a volunteer station, provided...
45 CFR 2551.61 - May a sponsor serve as a volunteer station?
Code of Federal Regulations, 2013 CFR
2013-10-01
... 45 Public Welfare 4 2013-10-01 2013-10-01 false May a sponsor serve as a volunteer station? 2551... NATIONAL AND COMMUNITY SERVICE SENIOR COMPANION PROGRAM Responsibilities of a Volunteer Station § 2551.61 May a sponsor serve as a volunteer station? Yes, a sponsor may serve as a volunteer station, provided...
45 CFR 2551.61 - May a sponsor serve as a volunteer station?
Code of Federal Regulations, 2014 CFR
2014-10-01
... 45 Public Welfare 4 2014-10-01 2014-10-01 false May a sponsor serve as a volunteer station? 2551... NATIONAL AND COMMUNITY SERVICE SENIOR COMPANION PROGRAM Responsibilities of a Volunteer Station § 2551.61 May a sponsor serve as a volunteer station? Yes, a sponsor may serve as a volunteer station, provided...
45 CFR 2551.61 - May a sponsor serve as a volunteer station?
Code of Federal Regulations, 2012 CFR
2012-10-01
... 45 Public Welfare 4 2012-10-01 2012-10-01 false May a sponsor serve as a volunteer station? 2551... NATIONAL AND COMMUNITY SERVICE SENIOR COMPANION PROGRAM Responsibilities of a Volunteer Station § 2551.61 May a sponsor serve as a volunteer station? Yes, a sponsor may serve as a volunteer station, provided...
45 CFR 2551.61 - May a sponsor serve as a volunteer station?
Code of Federal Regulations, 2010 CFR
2010-10-01
... 45 Public Welfare 4 2010-10-01 2010-10-01 false May a sponsor serve as a volunteer station? 2551... NATIONAL AND COMMUNITY SERVICE SENIOR COMPANION PROGRAM Responsibilities of a Volunteer Station § 2551.61 May a sponsor serve as a volunteer station? Yes, a sponsor may serve as a volunteer station, provided...
45 CFR 2552.61 - May a sponsor serve as a volunteer station?
Code of Federal Regulations, 2011 CFR
2011-10-01
... 45 Public Welfare 4 2011-10-01 2011-10-01 false May a sponsor serve as a volunteer station? 2552... NATIONAL AND COMMUNITY SERVICE FOSTER GRANDPARENT PROGRAM Responsibilities of a Volunteer Station § 2552.61 May a sponsor serve as a volunteer station? Yes, a sponsor may serve as a volunteer station, provided...
45 CFR 2552.61 - May a sponsor serve as a volunteer station?
Code of Federal Regulations, 2010 CFR
2010-10-01
... 45 Public Welfare 4 2010-10-01 2010-10-01 false May a sponsor serve as a volunteer station? 2552... NATIONAL AND COMMUNITY SERVICE FOSTER GRANDPARENT PROGRAM Responsibilities of a Volunteer Station § 2552.61 May a sponsor serve as a volunteer station? Yes, a sponsor may serve as a volunteer station, provided...
45 CFR 2553.61 - When may a sponsor serve as a volunteer station?
Code of Federal Regulations, 2011 CFR
2011-10-01
... 45 Public Welfare 4 2011-10-01 2011-10-01 false When may a sponsor serve as a volunteer station... FOR NATIONAL AND COMMUNITY SERVICE THE RETIRED AND SENIOR VOLUNTEER PROGRAM Responsibilities of a Volunteer Station § 2553.61 When may a sponsor serve as a volunteer station? The sponsor may function as a...
20 CFR 416.1160 - What is deeming of income?
Code of Federal Regulations, 2013 CFR
2013-04-01
.... (3) Sponsor of an alien. If you are an alien who has a sponsor and you first apply for SSI benefits... is also your ineligible spouse or parent who lives with you, we use the appropriate spouse-to-spouse or parent-to-child deeming rules instead of the sponsor-to-alien rules. If you have a sponsor and...
20 CFR 416.1160 - What is deeming of income?
Code of Federal Regulations, 2011 CFR
2011-04-01
.... (3) Sponsor of an alien. If you are an alien who has a sponsor and you first apply for SSI benefits... is also your ineligible spouse or parent who lives with you, we use the appropriate spouse-to-spouse or parent-to-child deeming rules instead of the sponsor-to-alien rules. If you have a sponsor and...
20 CFR 416.1160 - What is deeming of income?
Code of Federal Regulations, 2010 CFR
2010-04-01
.... (3) Sponsor of an alien. If you are an alien who has a sponsor and you first apply for SSI benefits... is also your ineligible spouse or parent who lives with you, we use the appropriate spouse-to-spouse or parent-to-child deeming rules instead of the sponsor-to-alien rules. If you have a sponsor and...
20 CFR 416.1160 - What is deeming of income?
Code of Federal Regulations, 2014 CFR
2014-04-01
.... (3) Sponsor of an alien. If you are an alien who has a sponsor and you first apply for SSI benefits... is also your ineligible spouse or parent who lives with you, we use the appropriate spouse-to-spouse or parent-to-child deeming rules instead of the sponsor-to-alien rules. If you have a sponsor and...
20 CFR 416.1160 - What is deeming of income?
Code of Federal Regulations, 2012 CFR
2012-04-01
.... (3) Sponsor of an alien. If you are an alien who has a sponsor and you first apply for SSI benefits... is also your ineligible spouse or parent who lives with you, we use the appropriate spouse-to-spouse or parent-to-child deeming rules instead of the sponsor-to-alien rules. If you have a sponsor and...
Reporting of Navy Sponsor Owned Material Stored at the Naval Air Systems Command Activities
2007-04-23
Who Should Read This Report and Why? Navy personnel responsible for reporting the amount and value of Sponsor Owned Material stored at Navy facilities should read this report. It discusses the financial reporting and control of Sponsor Owned Material stored by Naval Air Systems Command activities. Background. The Department of the Navy reported $58.8 billion of Operating Materials and Supplies on its first quarter FY 2006 financial statements. This included a sub-category of supplies and materials termed Sponsor Owned Material. The Navy defines Sponsor
Evaluating alcoholics anonymous sponsor attributes using conjoint analysis.
Stevens, Edward B; Jason, Leonard A
2015-12-01
Alcoholics Anonymous (AA) considers sponsorship an important element of the AA program, especially in early recovery. 225 adult individuals who had experience as either a sponsor, sponsee, or both, participated in a hypothetical sponsor ranking exercise where five attributes were varied across three levels. Conjoint analysis was used to compute part-worth utility of the attributes and their levels for experience, knowledge, availability, confidentiality, and goal-setting. Differences in utilities by attribute were found where confidentiality had the greatest overall possible impact on utility and sponsor knowledge had the least. These findings suggest qualitative differences in sponsors may impact their effectiveness. Future research on AA should continue to investigate sponsor influence on an individual's overall recovery trajectory. Copyright © 2015 Elsevier Ltd. All rights reserved.
Synergistic Action of FOXP3 and TSC1 Pathways During Tumor Progression
2016-10-01
Tumor progression, Gene therapy, Transcriptional regulation, Post -translational modification ACCOMPLISHMENTS Our preliminary studies provide evidence...Annual PREPARED FOR: U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 DISTRIBUTION STATEMENT: Approved for...10. SPONSOR/MONITOR’S ACRONYM(S) U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 11. SPONSOR/MONITOR’S REPORT
ERIC Educational Resources Information Center
Hartmann, Anita
2011-01-01
In the current economic climate, many colleges and universities face similar challenges: the need to increase external sponsorship for research activities and the need to benefit from additional indirect cost recovery. Preparing funding proposals for submission to sponsors is a faculty behavior that can be modified by applying behavioral theory to…
Georgias, Christine; Grunow, Andrea; Olderog, Miriam; May, Alexander; Paulus, Ursula
2012-12-01
With the amendment to the German Drug Law in 2004, the conduct of clinical trials changed by at least two main aspects: (1) The principles of Good Clinical Practice (GCP) were implemented in the national legislation, and (2) for the first time, the function of the sponsor of a clinical trial and the clinical trial itself have become legally binding definitions. By that, legal differences between industrial and academic clinical trials no longer exist. Clinical trials initiated by investigators have to fulfil the same requirements while the entire sponsor responsibility has to be carried out by the Coordinating Investigator or his institution including implementation of a quality management system according to the GCP. The Cologne Sponsor Model is an effective approach with settings, structures, basic features, action, and reporting lines, as well as funding for clinical trials initiated in an academic environment. The University of Cologne assumes the sponsor responsibility for clinical trials organised by the university researchers according to law. Sponsor's duties are delegated to a central operational unit of the sponsor - the Clinical Trials Center Cologne - which further delegates duties to the Coordinating Investigator. Clinical Trials Center Cologne was established in 2002 to support the performance of clinical trials at the university by offering comprehensive advisory and practical services covering all aspects of study planning and conduct. Furthermore, a specialised division of its quality management department acts as an independent sponsor's Quality Assurance Unit. The Clinical Trials Center Cologne has established a quality management system consisting of different components (1) to enable a reasoned decision to subsequent delegation, (2) for risk-based surveillance of trial conduct (audits, monitoring-checks, and reports), and (3) support and training of the Coordinating Investigator. Double functions of persons and departments in the university environment sometimes make it difficult to define roles in such a model. Therefore, it is necessary to establish clear reporting lines and moreover to monitor regularly and carefully the roles and responsibilities. With the combination of central management and support, control and independence of the researchers, our model represents a 'risk-based' system that offers a sensible option that fulfils the requirements of legal regulations and GCP for trials organised within the university environment.
Wang, Jue; Shapira, Philip
2015-01-01
This study analyzes funding acknowledgments in scientific papers to investigate relationships between research sponsorship and publication impacts. We identify acknowledgments to research sponsors for nanotechnology papers published in the Web of Science during a one-year sample period. We examine the citations accrued by these papers and the journal impact factors of their publication titles. The results show that publications from grant sponsored research exhibit higher impacts in terms of both journal ranking and citation counts than research that is not grant sponsored. We discuss the method and models used, and the insights provided by this approach as well as it limitations.
Breast cancer screening education in the workplace.
Paskett, E D; Case, L D; Masten, K B; Phillips, K C
1994-01-01
This study examined the use of breast cancer screening education programs in 102 of the major workplaces in Forsyth County, North Carolina. Characteristics of workplaces that had sponsored such programs within the preceding three years were identified. Eighteen percent of the workplaces surveyed had offered breast cancer screening education programs. Factors that were directly related to having sponsored a program included the size of the workforce, the number of female employees, and the proportion of female employees over 40 years old. Characteristics related to health service activities in the workplace were also predictive. Neither the type of industry nor the insurance status of the workplace was significantly related to having sponsored a program.
Wang, Jue; Shapira, Philip
2015-01-01
This study analyzes funding acknowledgments in scientific papers to investigate relationships between research sponsorship and publication impacts. We identify acknowledgments to research sponsors for nanotechnology papers published in the Web of Science during a one-year sample period. We examine the citations accrued by these papers and the journal impact factors of their publication titles. The results show that publications from grant sponsored research exhibit higher impacts in terms of both journal ranking and citation counts than research that is not grant sponsored. We discuss the method and models used, and the insights provided by this approach as well as it limitations. PMID:25695739
[Features of Clinical Register of Chinese Medicine and Pharmacy Based on ClinicalTrials.gov. (USA)].
Lu, Peng-fei; Liao, Xing; Xie, Yan-ming; Wang, Zhi-guo
2015-11-01
In recent 10 years, clinical trials of Chinese medicine and pharmacy (cMP) at clinicalTrials.gov.(USA) are gradually increasing. In order to analyze features of CMP clinical register, ClinicalTrials.gov register database were comprehensively retrieved in this study. Included clinical trials were input one item after another using EXCEL. A final of 348 CMP clinical trials were included. Results showed that China occupied the first place in CMP clinical register, followed by USA. CMP clinical trials, sponsored mainly by colleges/universities and hospitals, mostly covered interventional studies on evaluating safety/effectiveness of CMP. The proportions of studies, sponsored by mainland China and companies, recruitment trials and multi-center clinical trials in interventional trials were increasing. The proportions of studies sponsored by Hong Kong and Taiwan, research completed trials, unclear research status, phase III clinical trials, and published research trials in interventional trials were decreasing. Published ratios of CMP clinical trials were quite low. There were more missing types and higher proportions in trial register information.
Code of Federal Regulations, 2014 CFR
2014-10-01
... employee of the sponsor or of the volunteer station? 2552.45 Section 2552.45 Public Welfare Regulations... federal employee, an employee of the sponsor or of the volunteer station? Foster Grandparents are volunteers, and are not employees of the sponsor, the volunteer station, the Corporation, or the Federal...
Code of Federal Regulations, 2010 CFR
2010-10-01
... employee of the sponsor or of the volunteer station? 2552.45 Section 2552.45 Public Welfare Regulations... federal employee, an employee of the sponsor or of the volunteer station? Foster Grandparents are volunteers, and are not employees of the sponsor, the volunteer station, the Corporation, or the Federal...
Code of Federal Regulations, 2012 CFR
2012-10-01
... employee of the sponsor or of the volunteer station? 2551.45 Section 2551.45 Public Welfare Regulations... federal employee, an employee of the sponsor or of the volunteer station? Senior Companions are volunteers, and are not employees of the sponsor, the volunteer station, the Corporation, or the Federal...
Code of Federal Regulations, 2013 CFR
2013-10-01
... employee of the sponsor or of the volunteer station? 2552.45 Section 2552.45 Public Welfare Regulations... federal employee, an employee of the sponsor or of the volunteer station? Foster Grandparents are volunteers, and are not employees of the sponsor, the volunteer station, the Corporation, or the Federal...
Code of Federal Regulations, 2011 CFR
2011-10-01
... employee of the sponsor or of the volunteer station? 2551.45 Section 2551.45 Public Welfare Regulations... federal employee, an employee of the sponsor or of the volunteer station? Senior Companions are volunteers, and are not employees of the sponsor, the volunteer station, the Corporation, or the Federal...
Code of Federal Regulations, 2012 CFR
2012-10-01
... employee of the sponsor or of the volunteer station? 2552.45 Section 2552.45 Public Welfare Regulations... federal employee, an employee of the sponsor or of the volunteer station? Foster Grandparents are volunteers, and are not employees of the sponsor, the volunteer station, the Corporation, or the Federal...
Code of Federal Regulations, 2013 CFR
2013-10-01
... employee of the sponsor or of the volunteer station? 2551.45 Section 2551.45 Public Welfare Regulations... federal employee, an employee of the sponsor or of the volunteer station? Senior Companions are volunteers, and are not employees of the sponsor, the volunteer station, the Corporation, or the Federal...
Code of Federal Regulations, 2014 CFR
2014-10-01
... employee of the sponsor or of the volunteer station? 2551.45 Section 2551.45 Public Welfare Regulations... federal employee, an employee of the sponsor or of the volunteer station? Senior Companions are volunteers, and are not employees of the sponsor, the volunteer station, the Corporation, or the Federal...
Code of Federal Regulations, 2011 CFR
2011-10-01
... employee of the sponsor or of the volunteer station? 2552.45 Section 2552.45 Public Welfare Regulations... federal employee, an employee of the sponsor or of the volunteer station? Foster Grandparents are volunteers, and are not employees of the sponsor, the volunteer station, the Corporation, or the Federal...
2016-12-07
many DoD sponsored MAV projects including one task from ARO and another one as part of Army/Navy/ NASA - sponsored VLRCOE at Maryland all requiring...has undertaken many DoD sponsored MAV projects including one task from ARO and another one as part of Army/Navy/ NASA sponsored Vertical Lift Research
8 CFR 213a.3 - Notice of change of address.
Code of Federal Regulations, 2010 CFR
2010-01-01
... SUPPORT ON BEHALF OF IMMIGRANTS § 213a.3 Notice of change of address. (a)(1) If the address of a sponsor... obligation under the affidavit of support remains in effect with respect to any sponsored immigrant, the... 213A(d)(2)(A) of the Act. (ii) If the sponsor, knowing that the sponsored immigrant has received any...
Industry sponsored anti-smoking ads and adolescent reactance: test of a boomerang effect.
Henriksen, L; Dauphinee, A L; Wang, Y; Fortmann, S P
2006-02-01
To examine whether adolescents' exposure to youth smoking prevention ads sponsored by tobacco companies promotes intentions to smoke, curiosity about smoking, and positive attitudes toward the tobacco industry. A randomised controlled experiment compared adolescents' responses to five smoking prevention ads sponsored by a tobacco company (Philip Morris or Lorillard), or to five smoking prevention ads sponsored by a non-profit organisation (the American Legacy Foundation), or to five ads about preventing drunk driving. A large public high school in California's central valley. A convenience sample of 9th and 10th graders (n = 832) ages 14-17 years. Perceptions of ad effectiveness, intention to smoke, and attitudes toward tobacco companies measured immediately after exposure. As predicted, adolescents rated Philip Morris and Lorillard ads less favourably than the other youth smoking prevention ads. Adolescents' intention to smoke did not differ as a function of ad exposure. However, exposure to Philip Morris and Lorillard ads engendered more favourable attitudes toward tobacco companies. This study demonstrates that industry sponsored anti-smoking ads do more to promote corporate image than to prevent youth smoking. By cultivating public opinion that is more sympathetic toward tobacco companies, the effect of such advertising is likely to be more harmful than helpful to youth.
... Gold Sponsor NSPC Brain & Spine Surgery Learn More Gold Sponsor University of Colorado Acoustic Neuroma Program and Rocky Mountain Gamma Knife Center Learn More Gold Sponsor USC Acoustic Neuroma Center Learn More Gold ...
Alcohol sponsorship of community football clubs: the current situation.
Sawyer, Amy L; Wolfenden, Luke; Kennedy, Vanessa J; Kingsland, Melanie; Young, Kylie G; Tindall, Jennifer; Rowland, Bosco C; Colbran, Richard W; Wiggers, John H
2012-04-01
There is accumulating evidence supporting a link between alcohol industry sponsorship and alcohol-related problems in both community and elite-level sports. Little is known, however, about the current status of such sponsorship, particularly of community sport. This study aimed to assess associations between alcohol industry sponsorship and different community football clubs in Australia. The study involved 101 community football clubs across New South Wales, Australia. One representative from each club took part in a cross-sectional telephone survey designed to assess club (football code, number of players, socioeconomic and geographic descriptors) and alcohol industry sponsorship (money, equipment, free alcohol or discounted alcohol) characteristics. Chi-square analysis was used to test associations between club characteristics, and: i) any alcohol industry sponsorship; and ii) type of sponsorship. Eighty-eight per cent of clubs reported receiving sponsorship from the alcohol industry, and most clubs (82%) were sponsored by a licensed premises. There were no significant associations between club characteristics and source of alcohol industry sponsorship. However, small clubs were found to be significantly more likely to receive free or discounted alcohol sponsorship than larger clubs (p=0.05). This exploratory study suggests a significant presence of alcohol industry sponsorship among community football clubs in Australia.
Green, Cynthia L; Kligfield, Paul; George, Samuel; Gussak, Ihor; Vajdic, Branislav; Sager, Philip; Krucoff, Mitchell W
2012-03-01
The Cardiac Safety Research Consortium (CSRC) provides both "learning" and blinded "testing" digital electrocardiographic (ECG) data sets from thorough QT (TQT) studies annotated for submission to the US Food and Drug Administration (FDA) to developers of ECG analysis technologies. This article reports the first results from a blinded testing data set that examines developer reanalysis of original sponsor-reported core laboratory data. A total of 11,925 anonymized ECGs including both moxifloxacin and placebo arms of a parallel-group TQT in 181 subjects were blindly analyzed using a novel ECG analysis algorithm applying intelligent automation. Developer-measured ECG intervals were submitted to CSRC for unblinding, temporal reconstruction of the TQT exposures, and statistical comparison to core laboratory findings previously submitted to FDA by the pharmaceutical sponsor. Primary comparisons included baseline-adjusted interval measurements, baseline- and placebo-adjusted moxifloxacin QTcF changes (ddQTcF), and associated variability measures. Developer and sponsor-reported baseline-adjusted data were similar with average differences <1 ms for all intervals. Both developer- and sponsor-reported data demonstrated assay sensitivity with similar ddQTcF changes. Average within-subject SD for triplicate QTcF measurements was significantly lower for developer- than sponsor-reported data (5.4 and 7.2 ms, respectively; P < .001). The virtually automated ECG algorithm used for this analysis produced similar yet less variable TQT results compared with the sponsor-reported study, without the use of a manual core laboratory. These findings indicate that CSRC ECG data sets can be useful for evaluating novel methods and algorithms for determining drug-induced QT/QTc prolongation. Although the results should not constitute endorsement of specific algorithms by either CSRC or FDA, the value of a public domain digital ECG warehouse to provide prospective, blinded comparisons of ECG technologies applied for QT/QTc measurement is illustrated. Copyright © 2012 Mosby, Inc. All rights reserved.
Green, Cynthia L.; Kligfield, Paul; George, Samuel; Gussak, Ihor; Vajdic, Branislav; Sager, Philip; Krucoff, Mitchell W.
2013-01-01
Background The Cardiac Safety Research Consortium (CSRC) provides both “learning” and blinded “testing” digital ECG datasets from thorough QT (TQT) studies annotated for submission to the US Food and Drug Administration (FDA) to developers of ECG analysis technologies. This manuscript reports the first results from a blinded “testing” dataset that examines Developer re-analysis of original Sponsor-reported core laboratory data. Methods 11,925 anonymized ECGs including both moxifloxacin and placebo arms of a parallel-group TQT in 191 subjects were blindly analyzed using a novel ECG analysis algorithm applying intelligent automation. Developer measured ECG intervals were submitted to CSRC for unblinding, temporal reconstruction of the TQT exposures, and statistical comparison to core laboratory findings previously submitted to FDA by the pharmaceutical sponsor. Primary comparisons included baseline-adjusted interval measurements, baseline- and placebo-adjusted moxifloxacin QTcF changes (ddQTcF), and associated variability measures. Results Developer and Sponsor-reported baseline-adjusted data were similar with average differences less than 1 millisecond (ms) for all intervals. Both Developer and Sponsor-reported data demonstrated assay sensitivity with similar ddQTcF changes. Average within-subject standard deviation for triplicate QTcF measurements was significantly lower for Developer than Sponsor-reported data (5.4 ms and 7.2 ms, respectively; p<0.001). Conclusion The virtually automated ECG algorithm used for this analysis produced similar yet less variable TQT results compared to the Sponsor-reported study, without the use of a manual core laboratory. These findings indicate CSRC ECG datasets can be useful for evaluating novel methods and algorithms for determining QT/QTc prolongation by drugs. While the results should not constitute endorsement of specific algorithms by either CSRC or FDA, the value of a public domain digital ECG warehouse to provide prospective, blinded comparisons of ECG technologies applied for QT/QTc measurement is illustrated. PMID:22424006
ERIC Educational Resources Information Center
Cartwright, Desmond S.; And Others
The task group report presented in this publication is one of a series prepared by eminent psychologists who have served as consultants in the U.S.O.E.-sponsored grant study to conduct a Critical Appraisal of the Personality-Emotions-Motivation Domain. In order to achieve the goal of identifying important problems and areas for new research and…
ERIC Educational Resources Information Center
Loehlin, John C.; And Others
The task group report presented in this publication is one of a series prepared by eminent psychologists who have served as consultants in the U.S.O.E.-sponsored grant study to conduct a Critical Appraisal of the Personality-Emotions-Motivation Domain. In order to attain the goal of identifying important problems and areas for new research and…
ERIC Educational Resources Information Center
Smith, G. B.
Employer-sponsored recurrent (or lifelong) learning has grown from its World War II beginnings to become a large, important, but little-studied aspect of American education, one with major implications for the U.S. economy and society. U.S. employers spend from 20 to 100 billion dollars on educational programs for anywhere from 37 to 73 million…
The Evolution of Adjudicative Guidelines in the Department of Defense
2011-09-01
7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Defense Personnel Security Research Center 20 Ryan Ranch Road, Suite 290 Monterey, CA 93940...8. PERFORMING ORGANIZATION REPORT NUMBER PERSEREC: Technical Report 11-04 10. SPONSORING/MONITOR’S ACRONYM(S) 9. SPONSORING/MONITORING AGENCY...social science literature and organized for policy-makers. Other studies looked at aspects of the adjudication process, such as the use of
2015-05-15
Method for Amphibious Operations 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) Major Kevin J...7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBER Joint Military...SPONSORING/MONITORING AGENCY NAME( S ) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM( S ) 11 SPONSOR/MONITOR’S REPORT 11. SPONSOR
Differential Globalization of Industry- and Non-Industry-Sponsored Clinical Trials.
Atal, Ignacio; Trinquart, Ludovic; Porcher, Raphaël; Ravaud, Philippe
2015-01-01
Mapping the international landscape of clinical trials may inform global health research governance, but no large-scale data are available. Industry or non-industry sponsorship may have a major influence in this mapping. We aimed to map the global landscape of industry- and non-industry-sponsored clinical trials and its evolution over time. We analyzed clinical trials initiated between 2006 and 2013 and registered in the WHO International Clinical Trials Registry Platform (ICTRP). We mapped single-country and international trials by World Bank's income groups and by sponsorship (industry- vs. non- industry), including its evolution over time from 2006 to 2012. We identified clusters of countries that collaborated significantly more than expected in industry- and non-industry-sponsored international trials. 119,679 clinical trials conducted in 177 countries were analysed. The median number of trials per million inhabitants in high-income countries was 100 times that in low-income countries (116.0 vs. 1.1). Industry sponsors were involved in three times more trials per million inhabitants than non-industry sponsors in high-income countries (75.0 vs. 24.5) and in ten times fewer trials in low- income countries (0.08 vs. 1.08). Among industry- and non-industry-sponsored trials, 30.3% and 3.2% were international, respectively. In the industry-sponsored network of collaboration, Eastern European and South American countries collaborated more than expected; in the non-industry-sponsored network, collaboration among Scandinavian countries was overrepresented. Industry-sponsored international trials became more inter-continental with time between 2006 and 2012 (from 54.8% to 67.3%) as compared with non-industry-sponsored trials (from 42.4% to 37.2%). Based on trials registered in the WHO ICTRP we documented a substantial gap between the globalization of industry- and non-industry-sponsored clinical research. Only 3% of academic trials but 30% of industry trials are international. The latter appeared to be conducted in preferentially selected countries.
Differential Globalization of Industry- and Non-Industry–Sponsored Clinical Trials
Atal, Ignacio; Trinquart, Ludovic; Porcher, Raphaël; Ravaud, Philippe
2015-01-01
Background Mapping the international landscape of clinical trials may inform global health research governance, but no large-scale data are available. Industry or non-industry sponsorship may have a major influence in this mapping. We aimed to map the global landscape of industry- and non-industry–sponsored clinical trials and its evolution over time. Methods We analyzed clinical trials initiated between 2006 and 2013 and registered in the WHO International Clinical Trials Registry Platform (ICTRP). We mapped single-country and international trials by World Bank's income groups and by sponsorship (industry- vs. non- industry), including its evolution over time from 2006 to 2012. We identified clusters of countries that collaborated significantly more than expected in industry- and non-industry–sponsored international trials. Results 119,679 clinical trials conducted in 177 countries were analysed. The median number of trials per million inhabitants in high-income countries was 100 times that in low-income countries (116.0 vs. 1.1). Industry sponsors were involved in three times more trials per million inhabitants than non-industry sponsors in high-income countries (75.0 vs. 24.5) and in ten times fewer trials in low- income countries (0.08 vs. 1.08). Among industry- and non-industry–sponsored trials, 30.3% and 3.2% were international, respectively. In the industry-sponsored network of collaboration, Eastern European and South American countries collaborated more than expected; in the non-industry–sponsored network, collaboration among Scandinavian countries was overrepresented. Industry-sponsored international trials became more inter-continental with time between 2006 and 2012 (from 54.8% to 67.3%) as compared with non-industry–sponsored trials (from 42.4% to 37.2%). Conclusions Based on trials registered in the WHO ICTRP we documented a substantial gap between the globalization of industry- and non-industry–sponsored clinical research. Only 3% of academic trials but 30% of industry trials are international. The latter appeared to be conducted in preferentially selected countries. PMID:26658791
Dainesi, Sonia Mansoldo; Goldbaum, Moisés
2012-12-01
The growth of Internet users enables epidemiological studies to be conducted electronically, representing a promising methodology for data collection. Members of Ethics Committees, Clinical Researchers and Sponsors were interviewed using questionnaires sent over the Internet. Along with the questionnaire, participants received a message explaining the survey and also the informed consent. Returning the questionnaire meant the consent of the participant was given. No incentive was offered; two reminders were sent. The response rate was 21% (124/599), 20% (58/290) and 45% (24/53) respectively for Ethics Committees, Researchers and Sponsors. The percentage of return before the two reminders was about 62%. Reasons for non-response: participant not found, refusal to participate, lack of experience in clinical research or in the therapeutic field. Characteristics of participants: 45% of Ethics Committee participants, 64% of Researchers and 63% of Sponsors were male; mean age (range), respectively: 47 (28-74), 53 (24-72) and 40 (29-65) years. Among Researchers and Sponsors, all respondents had at least a university degree and, in the Ethics Committees group, only two (1.7%) did not have one. Most of the questionnaires in all groups came from the Southeast Region of Brazil, probably reflecting the highest number of clinical trials and research professionals in this region. Despite the potential limitations of a survey done through the Internet, this study led to a response rate similar to what has been observed with other models, efficiency in obtaining responses (speed and quality), convenience for respondents and low cost.
Mooney, LaVerne A; Fay, Lorna
2016-07-18
To estimate the proportion of Pfizer-sponsored clinical trials that completed in 2010 and are published as manuscripts in the peer-reviewed literature, and to assess the manuscript development history. Retrospective, cross-sectional analysis. Clinical trials registered in ClinicalTrials.gov that completed in 2010 for approved, Pfizer prescription products in patients or vaccines in healthy participants. The proportion of studies for which the primary outcome(s) was published and the median time from study completion to publication. The manuscript development history included the number of times a manuscript was submitted before it was accepted for publication. Among registered clinical trials for which Pfizer was the sponsor that completed in 2010, 76 met all inclusion criteria. The primary outcome(s) for 65 (85%) studies was published in 71 manuscripts; the median time to publication was 31 months (range 3-63 months). Of the remaining 11 studies, 2 had been submitted to at least one journal, 2 had not yet been submitted and 7 had no plans to publish because the study had terminated early due to recruitment challenges. Manuscripts accepted at the first choice journal were published at median time of 28 months (range 8-63, n=31), those accepted at second choice journal were published at 32 months (3-45, n=19), and for those accepted at third choice journal, it was 40 months (range 24-53, n=13). The publication rate and median time to publication from study completion for Pfizer-sponsored studies were comparable to those previously reported for combined analyses of industry and non-industry sectors. Opportunities exist for sponsors, authors and journals to explore ideas that would facilitate more timely publication for clinical trial results. However, to be effective, such changes may need to revisit the entire publication process. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/
Changing dynamics in employer-sponsored health insurance. One market's perspective.
Draper, D A; Thompson, J M; Hurley, R E
1999-01-01
Using their sponsored health benefits as a mechanism for change, employers have been able to exert significant influence over the nation's health care system. By examining how employers design, purchase and manage these programs, much insight can be gained. Twenty-five mid- to large-sized companies in a Middle-Atlantic metropolitan area were interviewed during May-July 1998. The study was modeled after a similar effort conducted in 1991, the results of which were published in this journal in 1993. The study found that many of the dynamics in employer-sponsored health insurance are changing. The findings suggest that a more distanced relationship between employers and employees is the major factor underlying the evolution, an intentional change to force a shift in medical care decision-making and responsibility to more of a shared process between the employee and the employer. These trends have important implications for local markets relevance and the national situation.
Sponsor-Imposed Publication Restrictions Disclosed on ClinicalTrials.gov.
Stretton, Serina; Lew, Rebecca A; Ely, Julie A; Snape, Mark J; Carey, Luke C; Haley, Cassandra; Woolley, Mark J; Woolley, Karen L
2016-01-01
We investigated whether sponsor-imposed publication restrictions for ClinicalTrials.gov trials were reasonable, based on consistency with Good Publication Practice 2 (GPP2). ClinicalTrials.gov trial record data were electronically imported (October 7, 2012) and screened for eligibility (phase 2-4, interventional, recruitment closed, results available, first received for registration after November 10, 2009, any sponsor type, investigators not sponsor employees). Two authors categorized restrictions information as consistent or not consistent with GPP2, resolving discrepancies by consensus. Of the eligible trials (388/484, n = 81,768 participants), 80.7% (313/388) had restrictions disclosed, and 92.5% (311/388) were industry-sponsored. Significantly more trials had restrictions that were consistent with GPP2 than not (74.1% [232/313], n = 55,280 participants vs. 25.9% [81/313], n = 19,677 participants; P < .001). Reasons for inconsistency were insufficient, unclear, or ambiguous information (48.1%, 39/81), sponsor-required approval for publication (35.8%, 29/81), sponsor-required text changes (8.6%, 7/81), and outright bans (7.4%, 6/81). Follow-up of trials with insufficient information and a contact email (response rate, 46.9% [15/32]) revealed 2 additional bans. A total of 776 participants had consented to trials that had publication bans. Many, but not all, sponsor-imposed publication restrictions disclosed on ClinicalTrials.gov may be considered reasonable. Sponsors should ensure restrictions are appropriately disclosed. Volunteers should be alerted to any restrictions before consenting to participate in a clinical trial.
Analyzing global trends of biomarker use in drug interventional clinical studies.
Hayashi, K; Masuda, S; Kimura, H
2012-04-01
The trend of biomarker use in drug interventional clinical studies was analyzed using ClinicalTrials.gov to provide an overview of how biomarkers are used to streamline clinical studies and to examine regional differences. A total of 3,383 clinical study data was analyzed according to phase, region, sponsor, and therapeutic class. The number of clinical studies using biomarkers has been increasing constantly and is dependent on the number of Phase I and II studies. The majority of studies (58.5%) were sponsored by the United States, with the studies being conducted mainly in the sponsor's home region (80.3%). The use of biomarkers was prominent in the oncology area (37.1%). Although current data indicates some bias in the clinical use of biomarkers, it is expected that their use will increase in later phase studies or other therapeutic areas as biomarker development proceeds. In addition, limited regional use of biomarkers may lead to differences in biomarker use in drug development and in combination with political support may result in differences in competitiveness of drug development. Biomarkers would be a powerful tool against deteriorating research and development productivity when used more in appropriate clinical study conditions.
20 CFR 416.1166a - How we deem income to you from your sponsor if you are an alien.
Code of Federal Regulations, 2013 CFR
2013-04-01
... if you are an alien. 416.1166a Section 416.1166a Employees' Benefits SOCIAL SECURITY ADMINISTRATION... income to you from your sponsor if you are an alien. Before we deem your sponsor's income to you if you are an alien, we determine how much earned and unearned income your sponsor has under § 416.1161(b...
20 CFR 416.1166a - How we deem income to you from your sponsor if you are an alien.
Code of Federal Regulations, 2014 CFR
2014-04-01
... if you are an alien. 416.1166a Section 416.1166a Employees' Benefits SOCIAL SECURITY ADMINISTRATION... income to you from your sponsor if you are an alien. Before we deem your sponsor's income to you if you are an alien, we determine how much earned and unearned income your sponsor has under § 416.1161(b...
20 CFR 416.1166a - How we deem income to you from your sponsor if you are an alien.
Code of Federal Regulations, 2012 CFR
2012-04-01
... if you are an alien. 416.1166a Section 416.1166a Employees' Benefits SOCIAL SECURITY ADMINISTRATION... income to you from your sponsor if you are an alien. Before we deem your sponsor's income to you if you are an alien, we determine how much earned and unearned income your sponsor has under § 416.1161(b...
20 CFR 416.1166a - How we deem income to you from your sponsor if you are an alien.
Code of Federal Regulations, 2011 CFR
2011-04-01
... if you are an alien. 416.1166a Section 416.1166a Employees' Benefits SOCIAL SECURITY ADMINISTRATION... income to you from your sponsor if you are an alien. Before we deem your sponsor's income to you if you are an alien, we determine how much earned and unearned income your sponsor has under § 416.1161(b...
45 CFR 2552.22 - What are the responsibilities of a sponsor?
Code of Federal Regulations, 2010 CFR
2010-10-01
... § 2552.22 What are the responsibilities of a sponsor? A sponsor is responsible for fulfilling all project management requirements necessary to accomplish the purposes of the Foster Grandparent Program as specified...
Asthma: NIH-Sponsored Research and Clinical Trials | NIH MedlinePlus the Magazine
... turn Javascript on. Feature: Asthma Asthma: NIH-Sponsored Research and Clinical Trials Past Issues / Fall 2011 Table of Contents NIH-Sponsored Research Asthma in the Inner City: Recognizing that asthma ...
AWEA WINDPOWER 2019 Conference & Exhibition
than go through menu items. Book a Booth Learn Exhibit Sponsor Register AWEA Wind Power May 20-23 2019 . Book Your Booth Sponsor Sponsoring AWEA WINDPOWER 2019 gives you the opportunity to broadcast your
45 CFR 2552.22 - What are the responsibilities of a sponsor?
Code of Federal Regulations, 2013 CFR
2013-10-01
... § 2552.22 What are the responsibilities of a sponsor? A sponsor is responsible for fulfilling all project management requirements necessary to accomplish the purposes of the Foster Grandparent Program as specified...
45 CFR 2552.22 - What are the responsibilities of a sponsor?
Code of Federal Regulations, 2014 CFR
2014-10-01
... § 2552.22 What are the responsibilities of a sponsor? A sponsor is responsible for fulfilling all project management requirements necessary to accomplish the purposes of the Foster Grandparent Program as specified...
45 CFR 2552.22 - What are the responsibilities of a sponsor?
Code of Federal Regulations, 2012 CFR
2012-10-01
... § 2552.22 What are the responsibilities of a sponsor? A sponsor is responsible for fulfilling all project management requirements necessary to accomplish the purposes of the Foster Grandparent Program as specified...
45 CFR 2552.22 - What are the responsibilities of a sponsor?
Code of Federal Regulations, 2011 CFR
2011-10-01
... § 2552.22 What are the responsibilities of a sponsor? A sponsor is responsible for fulfilling all project management requirements necessary to accomplish the purposes of the Foster Grandparent Program as specified...
Patterns of sports sponsorship by gambling, alcohol and food companies: an Internet survey.
Maher, Anthony; Wilson, Nick; Signal, Louise; Thomson, George
2006-04-11
Sports sponsorship is a significant marketing tool. As such, it can promote products that pose risks to health (eg, high fat and high sugar foods) or it can promote health-supporting products (eg, sporting equipment and services). However, there is a lack of data on the proportion of sponsorship associated with "unhealthy" and "healthy" products and no methodology for systematically assessing it. This research aimed to explore this proportion with an Internet survey of sports sponsorship in the New Zealand setting. A search methodology was developed to identify Internet-based evidence of sports sponsorship at the national level and at the regional and club level in one specific region (Wellington). The top eight sports for 5-17-year-olds were selected and products and services of sponsors were classified in terms of potential public health impact (using a conservative approach). Sponsorship of these popular sports was common at the national, regional and club levels (640 sponsors listed on 107 websites overall). Sports sponsorship associated with sponsors' products classified as "unhealthy" (eg, food high in fat and sugar, gambling and alcohol) were over twice as common as sponsorship associated with sponsors' products classified as "healthy" (32.7% (95% CI = 29.1, 36.5) versus 15.5% (95% CI = 12.8, 18.6) respectively). "Gambling" was the most common specific type of sponsorship (18.8%) followed by alcohol (11.3%). There were significantly more "alcohol" sponsors for rugby, compared to all the other sports collectively (rate ratio (RR) = 2.47; 95% CI = 1.60, 3.79), and for top male sports compared to female (RR = 1.83; 95% CI = 1.05, 3.18). Also there was significantly more "unhealthy food" sponsorship for touch rugby and for "junior" teams/clubs compared to other sports collectively (RR = 6.54; 95% CI = 2.07, 20.69; and RR = 14.72, 95% CI = 6.22, 34.8; respectively). A validation study gave an inter-rater reliability for number of sponsors of 95% (n = 87 sponsors), and an inter-rater reliability of classification and categorisation of 100%. This study found that the sponsorship of popular sports for young people is dominated by "unhealthy" sponsorship (ie, predominantly gambling, alcohol and unhealthy food) relative to "healthy" sponsorship. Governments may need to consider regulations that limit unhealthy sponsorship and/or adopt alternative funding mechanisms for supporting popular sports.
A comparison of mail-service and retail community pharmacy claims in 5 prescription benefit plans.
Clark, Bartholomew E; Siracuse, Mark V; Garis, Robert I
2009-06-01
Little evidence has been presented to date that would either support or refute a widely held belief that mail-service pharmacy utilization routinely produces savings in drug benefit costs for prescription benefit plan sponsors. To present a comparative analysis of mail-service and community pharmacy service drug benefit costs for 5 employer-sponsored prescription drug benefit plans. A cross-sectional comparison of 17,725 matched transaction pairs of community and mail-service prescriptions from a data set comprised 484,987 prescription claims from a convenience sample of 5 employer-sponsored prescription benefit plans. Differences between community pharmacy and mail-service prescription transactions were examined at the per-unit level of analysis for drug ingredient costs, dispensing fees, co-payments, dollar amounts paid by plan sponsor, and total dollar amounts. Overall, the total cost of prescriptions was lower through mail-service pharmacies for all 5 plans studied. Two of 5 plans had co-payment incentives to use mail-service, yet plan sponsors paid more for mail-service drugs; respectively, 4.5% and 8.3% more overall, 25.0% and 21.4% more for generic medications; and 3.0% and 7.0% more for brand name medications. Mail-service co-payments were 48.9% and 51.7% lower. Mail-service utilization rates were 15.2% and 31.5% of the total number of prescriptions dispensed in the period studied. Three of 5 plans had no co-payment incentive to use mail-service and paid less for mail-service drugs; respectively, 18.7%, 6.6%, and 15.7% less overall; 17.4%, 15.6%, and 7.9% less for generic medications; and 18.8%, 5.2%, and 16.6% less for brand name medications. Mail-service co-payments were 10.5% more, 5.2% less, and 1.8% more than community pharmacy co-payments, respectively. Mail-service utilization rates were 0.8%, 1.2%, and 4.4%. Co-payment incentives to use mail-service pharmacies instead of community pharmacies were associated with higher mail-service utilization rates and with higher costs to plan sponsors. Absence of a co-payment incentive to use mail-service pharmacies was associated with lower mail-service utilization rates and with lower costs to plan sponsors.
Patterns of sports sponsorship by gambling, alcohol and food companies: an Internet survey
Maher, Anthony; Wilson, Nick; Signal, Louise; Thomson, George
2006-01-01
Background Sports sponsorship is a significant marketing tool. As such, it can promote products that pose risks to health (eg, high fat and high sugar foods) or it can promote health-supporting products (eg, sporting equipment and services). However, there is a lack of data on the proportion of sponsorship associated with "unhealthy" and "healthy" products and no methodology for systematically assessing it. This research aimed to explore this proportion with an Internet survey of sports sponsorship in the New Zealand setting. Methods A search methodology was developed to identify Internet-based evidence of sports sponsorship at the national level and at the regional and club level in one specific region (Wellington). The top eight sports for 5-17-year-olds were selected and products and services of sponsors were classified in terms of potential public health impact (using a conservative approach). Results Sponsorship of these popular sports was common at the national, regional and club levels (640 sponsors listed on 107 websites overall). Sports sponsorship associated with sponsors' products classified as "unhealthy" (eg, food high in fat and sugar, gambling and alcohol) were over twice as common as sponsorship associated with sponsors' products classified as "healthy" (32.7% (95% CI = 29.1, 36.5) versus 15.5% (95% CI = 12.8, 18.6) respectively). "Gambling" was the most common specific type of sponsorship (18.8%) followed by alcohol (11.3%). There were significantly more "alcohol" sponsors for rugby, compared to all the other sports collectively (rate ratio (RR) = 2.47; 95% CI = 1.60, 3.79), and for top male sports compared to female (RR = 1.83; 95% CI = 1.05, 3.18). Also there was significantly more "unhealthy food" sponsorship for touch rugby and for "junior" teams/clubs compared to other sports collectively (RR = 6.54; 95% CI = 2.07, 20.69; and RR = 14.72, 95% CI = 6.22, 34.8; respectively). A validation study gave an inter-rater reliability for number of sponsors of 95% (n = 87 sponsors), and an inter-rater reliability of classification and categorisation of 100%. Conclusion This study found that the sponsorship of popular sports for young people is dominated by "unhealthy" sponsorship (ie, predominantly gambling, alcohol and unhealthy food) relative to "healthy" sponsorship. Governments may need to consider regulations that limit unhealthy sponsorship and/or adopt alternative funding mechanisms for supporting popular sports. PMID:16608525
Soldiers and Statesmen: Civil Military Case Studies of the NATO Decision-Making Process.
1998-06-01
5. FUNDING NUMBERS 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Postgraduate School Monterey, CA 93943-5000 8. PERFORMING... ORGANIZATION REPORT NUMBER 9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSORING/ MONITORING AGENCY REPORT NUMBER 11. SUPPLEMENTARY...ABSTRACT (maximum 200 words) The North Atlantic Treaty Organization was organized on a two-track structure. The military part of the Alliance was to be
Complexity of the Writing Environment: A Case Study At The Edge Of Chaos
2004-01-01
investigate the possibilities and connections among complex adaptive systems and the writing processes of three Colorado State University students in an...Colorado State University 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S... University Fort Collins, CO 80523 Fall 2004 ii COLORADO STATE UNIVERSITY August 18, 2004 WE HEREBY RECOMMEND THAT THE THESIS PREPARED UNDER OUR SUPERVISION
Experiences to Go: Teaching with Intelligence Case Studies
2004-09-01
SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 12 . DISTRIBUTION/AVAILABILITY STATEMENT Approved for public release...opment (AID) and a public affairs specialist from the U.S. Information Service (USIS). There was no Marine Security Guard detachment. The Regional...also were present. At around 2100 hours, Pamela and the others heard a muffled explosion from the direction of the airport, some 12 kilo- meters away
ERIC Educational Resources Information Center
Stevens, Mary A.
A study was conducted in order to develop a systematic method for the evaluation of students' prior, non-sponsored learning for the award of college credit at Blackhawk College (Illinois). It was determined that a course designed to prepare the student for assessment of prior learning was the best way for the institution to provide assistance to…
2016-12-21
STINFO COPY) AIR FORCE RESEARCH LABORATORY MATERIALS AND MANUFACTURING DIRECTORATE WRIGHT-PATTERSON AIR FORCE BASE, OH 45433-7750 AIR FORCE MATERIEL...9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSORING/MONITORING AGENCY ACRONYM(S) Air Force Research Laboratory...removing excess cholesterol from arterial plaques. Gold nanoparticles (AuNPs) functionalized with apolipoprotein A-I and with the lipids 1,2
The role of private industry in pragmatic comparative effectiveness trials.
Buesching, Don P; Luce, Bryan R; Berger, Marc L
2012-03-01
Comparative effectiveness research (CER) includes pragmatic clinical trials (PCTs) to address 'real-world' effectiveness. CER interest would be expected to stimulate biopharmaceutical manufacturer PCT investment; however, this does not seem to be the case. In this article we identify all industry-sponsored PCT studies from 1996 to 2010; analyze them across a variety of characteristics, including sponsor, research question, design, comparators and results; and suggest methodological and policy changes to spur future manufacturer PCT investment. Nine 'naturalistic', head-to-head versus standard of care or similar agent PCTs were identified. Two included a 'usual care' arm. Chronic care trials' length averaged 12 months (range: 6-24 months), six of which reported equivocal or no difference in effectiveness; results of two chronic and the single acute care PCTs favored the sponsor drug. None reported the sponsor drug inferior. Of seven that evaluated utilization or costs, six reported no differences and four of five studies comparing brand-generic drugs reported no difference. Whereas private investment in PCTs is in the public interest, manufacturers apparently have not yet seen the business case. To induce investment, we propose several methodological and regulatory policy innovations designed to reduce business risk by decreasing outcome variability and increasing trial efficiency, flexibility and market applicability.
45 CFR 2551.22 - What are the responsibilities of a sponsor?
Code of Federal Regulations, 2010 CFR
2010-10-01
... § 2551.22 What are the responsibilities of a sponsor? A sponsor is responsible for fulfilling all project management requirements necessary to accomplish the purposes of the Senior Companion Program as specified in...
45 CFR 2551.22 - What are the responsibilities of a sponsor?
Code of Federal Regulations, 2011 CFR
2011-10-01
... § 2551.22 What are the responsibilities of a sponsor? A sponsor is responsible for fulfilling all project management requirements necessary to accomplish the purposes of the Senior Companion Program as specified in...
45 CFR 2551.22 - What are the responsibilities of a sponsor?
Code of Federal Regulations, 2014 CFR
2014-10-01
... § 2551.22 What are the responsibilities of a sponsor? A sponsor is responsible for fulfilling all project management requirements necessary to accomplish the purposes of the Senior Companion Program as specified in...
45 CFR 2551.22 - What are the responsibilities of a sponsor?
Code of Federal Regulations, 2012 CFR
2012-10-01
... § 2551.22 What are the responsibilities of a sponsor? A sponsor is responsible for fulfilling all project management requirements necessary to accomplish the purposes of the Senior Companion Program as specified in...
45 CFR 2551.22 - What are the responsibilities of a sponsor?
Code of Federal Regulations, 2013 CFR
2013-10-01
... § 2551.22 What are the responsibilities of a sponsor? A sponsor is responsible for fulfilling all project management requirements necessary to accomplish the purposes of the Senior Companion Program as specified in...
Biologically-Inspired Microrobots. Volume 3. Micro-Robot Based on Abstracted Biological Principles
2006-04-01
Roy E. Ritzmann, Jeremy Morrey and Andrew Horchler Se. TASK NUMBER Sf. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) 8...SPONSORING/MONITORING AGENCY NAME( S ) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM( S ) Sponsor: Defense Advanced Research Projects Agency (DARPA...Microsystems Technology Office (Elana Ethridge) 3701 North Fairfax Drive Arlington, VA 22203-1714 11. SPONSOR/MONITOR’S REPORT NUMBER( S ) NATICK/TR-05
Should Sponsors and DSMBs Share Interim Results Across Trials?
Shah, Seema K.; Dawson, Liza; Dixon, Dennis O.; Lie, Reidar K.
2011-01-01
Increasing numbers of multinational clinical trials have generated new ethical obligations of research sponsors and their DSMBs. Although sponsors and DSMBs clearly have ethical obligations to protect subjects in their trials, future patients, and the integrity of their trial, the obligations they have to protect subjects in other trials have been overlooked. When interim results from clinical trials can significantly affect the conduct of other trials and the welfare of the subjects in those trials, sponsors and DSMBs may have obligations to disclose results to the relevant parties. We propose that sponsors and DSMBs routinely work together in advance to develop a plan for disclosing relevant information in cases where it is necessary to protect the welfare of subjects in other trials. Channels of communication between sponsors, DSMBs, IRBs, and others involved in similar and concurrent trials will better protect both research participants and the integrity of the research enterprise. PMID:21937922
Parental employment, family structure, and child's health insurance.
Rolett, A; Parker, J D; Heck, K E; Makuc, D M
2001-01-01
To examine the impact of family structure on the relationship between parental employment characteristics and employer-sponsored health insurance coverage among children with employed parents in the United States. National Health Interview Survey data for 1993-1995 was used to estimate proportions of children without employer-sponsored health insurance, by family structure, separately according to maternal and paternal employment characteristics. In addition, relative odds of being without employer-sponsored insurance were estimated, controlling for family structure and child's age, race, and poverty status. Children with 2 employed parents were more likely to have employer-sponsored health insurance coverage than children with 1 employed parent, even among children in 2-parent families. However, among children with employed parents, the percentage with employer-sponsored health insurance coverage varied widely, depending on the hours worked, employment sector, occupation, industry, and firm size. Employer-sponsored health insurance coverage for children is extremely variable, depending on employment characteristics and marital status of the parents.
Industry sponsored anti‐smoking ads and adolescent reactance: test of a boomerang effect
Henriksen, L; Dauphinee, A L; Wang, Y; Fortmann, S P
2006-01-01
Objective To examine whether adolescents' exposure to youth smoking prevention ads sponsored by tobacco companies promotes intentions to smoke, curiosity about smoking, and positive attitudes toward the tobacco industry. Design A randomised controlled experiment compared adolescents' responses to five smoking prevention ads sponsored by a tobacco company (Philip Morris or Lorillard), or to five smoking prevention ads sponsored by a non‐profit organisation (the American Legacy Foundation), or to five ads about preventing drunk driving. Setting A large public high school in California's central valley. Subjects A convenience sample of 9th and 10th graders (n = 832) ages 14–17 years. Main outcome measures Perceptions of ad effectiveness, intention to smoke, and attitudes toward tobacco companies measured immediately after exposure. Results As predicted, adolescents rated Philip Morris and Lorillard ads less favourably than the other youth smoking prevention ads. Adolescents' intention to smoke did not differ as a function of ad exposure. However, exposure to Philip Morris and Lorillard ads engendered more favourable attitudes toward tobacco companies. Conclusions This study demonstrates that industry sponsored anti‐smoking ads do more to promote corporate image than to prevent youth smoking. By cultivating public opinion that is more sympathetic toward tobacco companies, the effect of such advertising is likely to be more harmful than helpful to youth. PMID:16436398
Game on: do children absorb sports sponsorship messages?
Pettigrew, Simone; Rosenberg, Michael; Ferguson, Renee; Houghton, Stephen; Wood, Lisa
2013-12-01
It is likely that there are substantial subconscious effects of organizations’ efforts to associate their products with sport via sponsorships, but most research methods are unable to capture these effects. The present study employed a novel projective technique to explore children's implicit associations between popular sports and a range of sports sponsors. Children participated in an activity using magnets bearing the logos of numerous sports and sponsors. They were invited to arrange the magnets on a whiteboard without being advised that the activity related to sponsorship. Perth, Western Australia. Children (n 164) aged 5–12 years. Three-quarters (76 %) of the children aligned at least one correct sponsor magnet with the relevant sport. Just over half the children (54 %) correctly matched the most popular sport (an Australian Football League team) with its relevant sponsor (a fast-food chain). Given the unstructured nature of the projective task, the results provide some support for the argument that sports sponsorship can effectively reach child audiences. This is of concern given the current extent of sponsorship by alcohol and fast-food companies.
Shen, Li-Jiuan; Chou, Hua; Huang, Chih-Fen; Chou, Guann-Miaw; Chan, Wing Kai; Wu, Fe-Lin Lin
2011-07-01
Concerns exist regarding the additional cost of patient care when patients are enrolled in clinical trials at hospitals. To assess the avoidance of drug costs by conducting sponsored clinical trials, a retrospective analysis evaluating drug cost avoidance in all sponsored clinical trials was conducted in 2008 at the most prominent medical center in Taiwan. The National Health Insurance (NHI) reimbursement prices of either the investigated drugs or the standardized drug therapy for each specific disease were used to calculate the cost avoidance. Drug cost avoidance from sponsored clinical trials per year, per trial, per patient, in different therapeutic areas, and in different phases was analyzed. Three quarters of the cost avoidance in drug expenditures from 194 sponsored clinical trials were estimated. All cost values are in US Dollars. Around $11.2 million was avoided at the center in 2008. The average value of cost avoidance was $58,000/trial-year or $3,900/participant-year. The early-phase trials and phase III trials accounted for 25% and 56% of all trials, respectively, while they constituted 32% and 49% of the total costs avoided, respectively. The most frequently conducted and highest cost-avoiding trials were those for antineoplastic agents, especially targeted therapy which accounted for 85% of the total cost avoidance of anti-cancer trials. This study demonstrates the profoundly positive economic impact on the healthcare system in Taiwan by sponsored clinical trials. To understand the trend of economic benefits of the trials on pharmaceutical expenditure, it would be important to analyze the cost avoidance of trials regularly in an institution. Copyright © 2011 Elsevier Inc. All rights reserved.
2013-09-03
SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11 . SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION... 11 Connecting technical risk and types of complexity...24 Figure 11 . Complexity evolution throughout the systems acquisition lifecycle ......................................... 25
NASA Astrophysics Data System (ADS)
Oliver, Howard
The aim of the NATO Science Committee's Global Transport Mechanisms in the Geosciences program is to stimulate and facilitate international collaboration among scientists of the member countries in the study of selected global transport mechanisms. The program organizers intend to sponsor advanced research workshops, advanced study institutes, conferences, collaborative research, research study, and lecture visits. NATO grants are available, but they are intended to cover only part of the expenses involved in the international aspects of the sponsored activities. Citizens or permanent residents of one of the member countries of NATO who possess qualifications appropriate to the proposed activity are eligible to apply.
Review and Analysis of Publication Trends over Three Decades in Three High Impact Medicine Journals.
Ivanov, Alexander; Kaczkowska, Beata A; Khan, Saadat A; Ho, Jean; Tavakol, Morteza; Prasad, Ashok; Bhumireddy, Geetha; Beall, Allan F; Klem, Igor; Mehta, Parag; Briggs, William M; Sacchi, Terrence J; Heitner, John F
2017-01-01
Over the past three decades, industry sponsored research expanded in the United States. Financial incentives can lead to potential conflicts of interest (COI) resulting in underreporting of negative study results. We hypothesized that over the three decades, there would be an increase in: a) reporting of conflict of interest and source of funding; b) percentage of randomized control trials c) number of patients per study and d) industry funding. Original articles published in three calendar years (1988, 1998, and 2008) in The Lancet, New England Journal of Medicine and Journal of American Medical Association were collected. Studies were reviewed and investigational design categorized as prospective and retrospective clinical trials. Prospective trials were categorized into randomized or non-randomized and single-center or multi-center trials. Retrospective trials were categorized as registries, meta-analyses and other studies, mostly comprising of case reports or series. Study outcomes were categorized as positive or negative depending on whether the pre-specified hypothesis was met. Financial disclosures were researched for financial relationships and profit status, and accordingly categorized as government, non-profit or industry sponsored. Studies were assessed for reporting COI. 1,671 original articles were included in this analysis. Total number of published studies decreased by 17% from 1988 to 2008. Over 20 year period, the proportion of prospective randomized trials increased from 22 to 46% (p < 0.0001); whereas the proportion of prospective non-randomized trials decreased from 59% to 27% (p < 0.001). There was an increase in the percentage of prospective randomized multi-center trials from 11% to 41% (p < 0.001). Conversely, there was a reduction in non-randomized single-center trials from 47% to 10% (p < 0.001). Proportion of government funded studies remained constant, whereas industry funded studies more than doubled (17% to 40%; p < 0.0001). The number of studies with negative results more than doubled (10% to 22%; p<0.0001). While lack of funding disclosure decreased from 35% to 7%, COI reporting increased from 2% to 84% (p < 0.0001). Improved reporting of COI, clarity in financial sponsorship, increased publication of negative results in the setting of larger and better designed clinical trials represents a positive step forward in the scientific publications, despite the higher percentage of industry funded studies.
Tax-exempt bonds and sponsored research.
Ballard, Frederic L
2003-01-01
"Sponsored research," wherein a business corporation or the government pays a portion of the cost of research activities carried out by a university or hospital, is increasingly important both for state institutions and for Section 510(c)(3) organizations. Sponsored research arrangements that are not properly structured can jeopardize the status of tax-exempt bonds issued to finance the facility at which the sponsored research occurs. While these rules have been difficult to apply in practice, properly structured agreements can provide funding for research without undue risk. This Article discusses the multiple pieces of guidance put forth by the Internal Revenue Service to clarify the many issues and tiers of analysis necessary to ensure a properly-structured sponsored research agreement.
AFOSR Indo-UK -US Joint Physics Initiative for Study of Angular Optical Mode Fiber Amplification
2017-02-20
AFRL -AFOSR-UK-TR-2017-0011 AFOSR Indo-UK -US Joint Physics Initiative for study of angular optical mode fiber amplification Johan Nilsson UNIVERSITY...ES) EOARD Unit 4515 APO AE 09421-4515 10. SPONSOR/MONITOR’S ACRONYM(S) AFRL /AFOSR IOE 11. SPONSOR/MONITOR’S REPORT NUMBER(S) AFRL -AFOSR-UK-TR-2017-0011...this travel, he had the opportunity to visit the Kirtland Air Force Base and interact with Dr Leanne Henry as well as Dr Iyad Dajani to discuss
; Current Students: Go inside.mines Home Operations Summary Corporate Sponsors Sponsor Access Staff Students fifty Industry/University Cooperative Research Centers. Thanks to corporate supporters from all over the corporate sponsors. © 2018 Colorado School of Mines | | Equal Opportunity | Privacy Policy | Directories
21 CFR 312.3 - Definitions and interpretations.
Code of Federal Regulations, 2011 CFR
2011-04-01
... research organization means a person that assumes, as an independent contractor with the sponsor, one or... individual or pharmaceutical company, governmental agency, academic institution, private organization, or other organization. The sponsor does not actually conduct the investigation unless the sponsor is a...
21 CFR 312.3 - Definitions and interpretations.
Code of Federal Regulations, 2010 CFR
2010-04-01
... research organization means a person that assumes, as an independent contractor with the sponsor, one or... individual or pharmaceutical company, governmental agency, academic institution, private organization, or other organization. The sponsor does not actually conduct the investigation unless the sponsor is a...
Code of Federal Regulations, 2010 CFR
2010-01-01
... AGRICULTURE WATER RESOURCES WATERSHED PROJECTS Qualifications § 622.10 Sponsors. (a) Watershed projects are... the use of nonstructural or structural measures shall be sponsored by organizations that, individually... project cost and all operation and maintenance costs. (b) To receive Federal assistance for project...
ERIC Educational Resources Information Center
College and University Business Administration, 1980
1980-01-01
General administrative principles and procedures applicable to any type of program sponsored by external funds, including the federal government, are examined. Contracts, grants, and cooperative agreements are the devices for authorizing sponsored programs. Since the institutions assume full legal responsibility for the programs and for fulfilling…
All Those Who Remained: The American-Led Guerillas in the Philippines, 1942-1945
2014-12-04
United States Army School of Advanced Military Studies United States Army Command and General Staff College Fort Leavenworth, Kansas 2014-02...SPONSOR/MONITOR’S ACRONYM(S) Command and General Staff College CGSC 731 McClellan Avenue Fort Leavenworth, KS 66027-1350 11. SPONSOR/MONITOR’S...Luzon through all phases of the campaign. This monograph evaluates the effectiveness of these American-led guerilla groups in supporting the US
Air Power and Counterinsurgency: A Strategic Study in Efficiency
2010-03-01
L. Daft , Karl E. Weick, “Toward a Model of Organizations as Interpretation Systems”, Academy of Management Review, 1984, Vol. 9, No.2, p. 71 36...5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Department of National Security and Strategy Dr. Tami...D. Biddle 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S
Detection of Ammonium Nitrate Variants by Canine: A Study of Generalization between Like Substances
2018-04-30
PERFORMING ORGANIZATION REPORT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 10. SPONSOR / MONITOR’S ACRONYM(S)9. SPONSORING / MONITORING...16 Figure 9. Alert rates for Group A, trained to prill fertilizer AN, and Group B, trained to ground fertilizer AN for Trial 2...thirds of all American deaths in combat were by IED attacks, according to the Joint IED Defeat Organization (JIEDDO, now the Joint Improvised- Threat
My Clan Against the World: US and Coalition Forces in Somalia, 1992-1994
2003-01-01
PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Combat Studies Institute Press,Fort Leavenworth...KS,66027 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11...and bewildering ascent along the spectrum of violence. What started as an apparently straightforward quest to assist humanitarian relief organizations
The Army War College Review. Volume 1, Number 1, February 2015
2015-02-01
PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) U.S. Army War College,Strategic Studies...leaders and those who are led. With time, honest and frank professional exchanges will build the kind of confidence necessary to voice dissent and...Institute,Carlisle Barracks,PA,17013 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR
Job Search on the Internet, E-Recruitment, and Labor Market Outcomes
2010-01-01
CA,90407-2138 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/ MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11...United States offered the option of telecommuting at least one day a week, according to a 2008 survey by the...expression can easily deviate from zero . To estimate an unbiased estimate of , which is the effect of 45 using the Internet, this study uses two
2006-09-01
ORGANIZATION NAME(S) AND ADDRESS( ES ) Naval Postgraduate School Monterey, CA 93943-5000 8. PERFORMING ORGANIZATION REPORT NUMBER 9...SPONSORING /MONITORING AGENCY NAME(S) AND ADDRESS( ES ) N/A 10. SPONSORING/MONITORING AGENCY REPORT NUMBER 11. SUPPLEMENTARY NOTES The views expressed...mounted in a SATEC load frame. Figure 4 is a schematic of the diffusion bonding chamber and associated equipment. Al/Si and Cu/Quartz samples were
Human and Organizational Risk Modeling: Critical Personnel and Leadership in Network Organizations
2006-08-01
NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Carnegie Mellon University,School of Computer...Science,Pittsburgh,PA,15213 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S...organization can help improve performance and protect against the risk of loss. But the study of critical personnel has traditionally used static structural
The Effect of Military Service and Skill Transferability on the Civilian Earnings of Veterans.
1998-03-01
as well as job performance . The impact of children on the post-service earnings of veterans has been examined in several studies. Hirsch and Mehay...AUTHOR(S) Petroff Steven J. 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Postgraduate School Monterey, CA 93943-5000 9. SPONSORING...MONITORING AGENCY NAME(S) AND ADDRESS(ES) 5. FUNDING NUMBERS 8. PERFORMING ORGANIZATION REPORT NUMBER 10. SPONSORING / MONITORING AGENCY REPORT
Small, Self-Contained Aircraft Fatigue Data Recorder.
1986-08-01
need to monitor structural fatigue damage on military aircraft has become critical. It is particularly important to be able to study the dynamic...serve to heighten concerns over the accumulation of fatigue damage . Accordingly, there is a requirement for a fatigue data recorder readily installed...report is to apprise the sponsor of the progress to date and to solicit comments from the sponsor on the report content and the direction the design is
The Zero Boil-Off Tank Experiment Ground Testing and Verification of Fluid and Thermal Performance
NASA Technical Reports Server (NTRS)
Chato, David J.; Kassemi, Mohammad; Kahwaji, Michel; Kieckhafer, Alexander
2016-01-01
The Zero Boil-Off Technology (ZBOT) Experiment involves performing a small scale International Space Station (ISS) experiment to study tank pressurization and pressure control in microgravity. The ZBOT experiment consists of a vacuum jacketed test tank filled with an inert fluorocarbon simulant liquid. Heaters and thermo-electric coolers are used in conjunction with an axial jet mixer flow loop to study a range of thermal conditions within the tank. The objective is to provide a high quality database of low gravity fluid motions and thermal transients which will be used to validate Computational Fluid Dynamic (CFD) modeling. This CFD can then be used in turn to predict behavior in larger systems with cryogens. This paper will discuss the work that has been done to demonstrate that the ZBOT experiment is capable of performing the functions required to produce a meaningful and accurate results, prior to its launch to the International Space Station. Main systems discussed are expected to include the thermal control system, the optical imaging system, and the tank filling system.This work is sponsored by NASAs Human Exploration Mission Directorates Physical Sciences Research program.
Mapping the literature of cytotechnology
Stevens, Sheryl R.
2000-01-01
The major purpose of this study was to identify and assess indexing coverage of core journals in cytotechnology. It was part of a larger project sponsored by the Nursing and Allied Health Resources Section of the Medical Library Association to map the literature of allied health. Three representative journals in cytotechnology were selected and subjected to citation analysis to determine what journals, other publication types, and years were cited and how often. Bradford's Law of Scattering was applied to the resulting list of cited journals to identify core titles in the discipline, and five indexes were searched to assess coverage of these core titles. Results indicated that the cytotechnology journal literature had a small core but wide dispersion: one third of the 21,021 journal citations appeared in only 3 titles; another third appeared in an additional 26 titles; the remaining third were scattered in 1,069 different titles. Science Citation Index Expanded rated highest in indexing coverage of the core titles, followed by MEDLINE, EMBASE/Excerpta Medica, HealthSTAR, and Cumulative Index to Nursing and Allied Health Literature (CINAHL). The study's results also showed that journals were the predominantly cited format and that citing authors relied strongly on more recent literature. PMID:10783973
22 CFR 211.5 - Obligations of cooperating sponsor.
Code of Federal Regulations, 2012 CFR
2012-04-01
... Standards promulgated by the International Organization of Supreme Audit Institutions or International... provisions of this regulation. (c) Audits—(1) By nongovernmental cooperating sponsors. A nongovernmental cooperating sponsor shall arrange for periodic audits to be conducted in accordance with OMB Circular A-133...
22 CFR 211.5 - Obligations of cooperating sponsor.
Code of Federal Regulations, 2013 CFR
2013-04-01
... Standards promulgated by the International Organization of Supreme Audit Institutions or International... provisions of this regulation. (c) Audits—(1) By nongovernmental cooperating sponsors. A nongovernmental cooperating sponsor shall arrange for periodic audits to be conducted in accordance with OMB Circular A-133...
22 CFR 211.5 - Obligations of cooperating sponsor.
Code of Federal Regulations, 2010 CFR
2010-04-01
... Standards promulgated by the International Organization of Supreme Audit Institutions or International... provisions of this regulation. (c) Audits—(1) By nongovernmental cooperating sponsors. A nongovernmental cooperating sponsor shall arrange for periodic audits to be conducted in accordance with OMB Circular A-133...
22 CFR 211.5 - Obligations of cooperating sponsor.
Code of Federal Regulations, 2011 CFR
2011-04-01
... Standards promulgated by the International Organization of Supreme Audit Institutions or International... provisions of this regulation. (c) Audits—(1) By nongovernmental cooperating sponsors. A nongovernmental cooperating sponsor shall arrange for periodic audits to be conducted in accordance with OMB Circular A-133...
22 CFR 211.5 - Obligations of cooperating sponsor.
Code of Federal Regulations, 2014 CFR
2014-04-01
... Standards promulgated by the International Organization of Supreme Audit Institutions or International... provisions of this regulation. (c) Audits—(1) By nongovernmental cooperating sponsors. A nongovernmental cooperating sponsor shall arrange for periodic audits to be conducted in accordance with OMB Circular A-133...
A Compilation of Articles Reporting Research Sponsored by the Office of Naval Research
1980-07-01
i-A /VGR P Technical Reports Nos 378,379,380,381 and 382 A COMPILATION OF ARTICLES REPORTING RESEARCH SPONSORED BY THE OFFICE OF NAVAL RESEARCH...SPONSORED BY ( THE OFFICE OF NAVAL RESEARCH#’ "I ZIP Office o ---- Contract JINY(601-Z.7-OO502IProject N 1 __ terge C, Anderson Associate Chairman for...SPONSORED BY THE OFFICE OF NAVAL RESEARCH TECHNICAL REPORT NO. 378 The Depth Variability of Meridional Gradients of Temperature, Salinity and Sound
Recent methodological advances in male hormonal contraception.
Liu, Peter Y; Swerdloff, Ronald S; Wang, Christina
2010-11-01
Landmark WHO-sponsored trials showed decades ago that male hormonal contraception (MHC) is an effective male-directed contraceptive approach. Considerable progress has been made particularly in the last 5 years, establishing for the first time the reversibility of MHC and its short-term safety. Methodological advances in recent years include the pooling of information and individual-level integrated analysis; the first-time use of centralized semen analysis and fluorescence to detect low sperm concentrations; the establishment of sperm quality reference ranges in fertile men; the measurement of blood steroid concentrations by gas chromatography/mass spectrometry; and the inclusion of placebo groups to delineate clearly possible adverse effects of androgens and progestins in men. We report integrated analyses of factors that are important in predicting suppression and recovery of spermatogenesis after MHC clinical trials for the past 15 years. These are the best data available and will provide guidance and reassurance for the larger-scale Phase III specific regimen efficacy studies that will be required to bring MHC to the population (market). Copyright © 2010 Elsevier Inc. All rights reserved.
Intracontinental rift comparisons: Baikal and Rio Grande Rift Systems
NASA Astrophysics Data System (ADS)
Lipman, P. W.; Logatchev, N. A.; Zorin, Y. A.; Chapman, C. E.; Kovalenko, V.; Morgan, P.
Both the Baikal rift in Siberia and the Rio Grande rift in New Mexico, Colorado and Texas are major intracontinental extensional structures of Cenozoic age that affect regions about 1500 km long and several hundred km wide (Figures 1, 2). In the summer of 1988 these rifts were visited by study groups of U.S. and Soviet geoscientists during cooperative field workshops sponsored by the Soviet Academy of Sciences, U.S. National Academy of Sciences, and U.S. Geological Survey.In the Rio Grande region, we spent 2 weeks examining rift features between El Paso, Tex., and Denver, Colo. Particular emphasis was on the sedimentary record of rift evolution, widespread volcanic activity from inception of rifting to the present, geophysical expression of rift features, and relations between rifting and the larger-scale evolution of the North American Cordillera. In the Baikal region, which presents formidable logistic problems for a workshop, we travelled by bus, truck, helicopter, and ship to examine young seismotectonic features, rift-related basalt, and bounding structures of the Siberian craton that influenced rift development (Figure 3).
Genetic Simulation Tools for Post-Genome Wide Association Studies of Complex Diseases
Amos, Christopher I.; Bafna, Vineet; Hauser, Elizabeth R.; Hernandez, Ryan D.; Li, Chun; Liberles, David A.; McAllister, Kimberly; Moore, Jason H.; Paltoo, Dina N.; Papanicolaou, George J.; Peng, Bo; Ritchie, Marylyn D.; Rosenfeld, Gabriel; Witte, John S.
2014-01-01
Genetic simulation programs are used to model data under specified assumptions to facilitate the understanding and study of complex genetic systems. Standardized data sets generated using genetic simulation are essential for the development and application of novel analytical tools in genetic epidemiology studies. With continuing advances in high-throughput genomic technologies and generation and analysis of larger, more complex data sets, there is a need for updating current approaches in genetic simulation modeling. To provide a forum to address current and emerging challenges in this area, the National Cancer Institute (NCI) sponsored a workshop, entitled “Genetic Simulation Tools for Post-Genome Wide Association Studies of Complex Diseases” at the National Institutes of Health (NIH) in Bethesda, Maryland on March 11-12, 2014. The goals of the workshop were to: (i) identify opportunities, challenges and resource needs for the development and application of genetic simulation models; (ii) improve the integration of tools for modeling and analysis of simulated data; and (iii) foster collaborations to facilitate development and applications of genetic simulation. During the course of the meeting the group identified challenges and opportunities for the science of simulation, software and methods development, and collaboration. This paper summarizes key discussions at the meeting, and highlights important challenges and opportunities to advance the field of genetic simulation. PMID:25371374
Redactions in protocols for drug trials: what industry sponsors concealed.
Marquardsen, Mikkel; Ogden, Michelle; Gøtzsche, Peter C
2018-04-01
Objective To describe the redactions in contemporary protocols for industry-sponsored randomised drug trials with patient relevant outcomes and to evaluate whether there was a legitimate rationale for the redactions. Design Cohort study. Under the Freedom of Information Act, we requested access to trial protocols approved by a research ethics committee in Denmark from October 2012 to March 2013. We received 17 consecutive protocols, which had been redacted before we got them, and nine protocols without redactions. In five additional cases, the companies refused to let the committees give us access, and in three other cases, documents were missing. Participants Not applicable. Setting Not applicable. Main outcome measure Amount and nature of redactions in 22 predefined key protocol variables. Results The redactions were most widespread in those sections of the protocol where there is empirical evidence of substantial problems with the trustworthiness of published drug trials: data analysis, handling of missing data, detection and analysis of adverse events, definition of the outcomes, interim analyses and premature termination of the study, sponsor's access to incoming data while the study is running, ownership to the data and investigators' publication rights. The parts of the text that were redacted differed widely, both between companies and within the same company. Conclusions We could not identify any legitimate rationale for the redactions. The current mistrust in industry-sponsored drug trials can only change if the industry offers unconditional access to its trial protocols and other relevant documents and data.
14 CFR 152.103 - Sponsors: Airport development.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Sponsors: Airport development. 152.103 Section 152.103 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... Sponsors: Airport development. (a) To be eligible to apply for a project for airport development with...
14 CFR 152.103 - Sponsors: Airport development.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Sponsors: Airport development. 152.103 Section 152.103 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... Sponsors: Airport development. (a) To be eligible to apply for a project for airport development with...
ERIC Educational Resources Information Center
Klein, Walter J.
For public relations professionals and would-be sponsors of films, this book provides guidelines for understanding the film medium and its potential as a persuasive force in industry, government, organizations, and religious orders. For filmmakers, it brings together practical information needed to survive in the sponsored-film industry and to…
45 CFR 1226.13 - Obligations of sponsors.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 45 Public Welfare 4 2010-10-01 2010-10-01 false Obligations of sponsors. 1226.13 Section 1226.13 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE PROHIBITIONS ON ELECTORAL AND LOBBYING ACTIVITIES Sponsor Employee Activities § 1226.13...
33 CFR 385.23 - Dispute resolution.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Processes § 385.23 Dispute resolution. (a) Disputes with the non-Federal sponsor concerning a Project... Cooperation Agreement. (b) Disputes with the non-Federal sponsor concerning design activities shall be... issues with the non-Federal sponsor and disputes with the State associated with the implementation of the...
33 CFR 385.23 - Dispute resolution.
Code of Federal Regulations, 2014 CFR
2014-07-01
... Processes § 385.23 Dispute resolution. (a) Disputes with the non-Federal sponsor concerning a Project... Cooperation Agreement. (b) Disputes with the non-Federal sponsor concerning design activities shall be... issues with the non-Federal sponsor and disputes with the State associated with the implementation of the...
33 CFR 385.23 - Dispute resolution.
Code of Federal Regulations, 2012 CFR
2012-07-01
... Processes § 385.23 Dispute resolution. (a) Disputes with the non-Federal sponsor concerning a Project... Cooperation Agreement. (b) Disputes with the non-Federal sponsor concerning design activities shall be... issues with the non-Federal sponsor and disputes with the State associated with the implementation of the...
33 CFR 385.23 - Dispute resolution.
Code of Federal Regulations, 2013 CFR
2013-07-01
... Processes § 385.23 Dispute resolution. (a) Disputes with the non-Federal sponsor concerning a Project... Cooperation Agreement. (b) Disputes with the non-Federal sponsor concerning design activities shall be... issues with the non-Federal sponsor and disputes with the State associated with the implementation of the...
14 CFR 152.103 - Sponsors: Airport development.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Sponsors: Airport development. 152.103... (CONTINUED) AIRPORTS AIRPORT AID PROGRAM Eligibility Requirements and Application Procedures § 152.103 Sponsors: Airport development. (a) To be eligible to apply for a project for airport development with...
14 CFR 152.103 - Sponsors: Airport development.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Sponsors: Airport development. 152.103... (CONTINUED) AIRPORTS AIRPORT AID PROGRAM Eligibility Requirements and Application Procedures § 152.103 Sponsors: Airport development. (a) To be eligible to apply for a project for airport development with...
14 CFR 152.103 - Sponsors: Airport development.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Sponsors: Airport development. 152.103... (CONTINUED) AIRPORTS AIRPORT AID PROGRAM Eligibility Requirements and Application Procedures § 152.103 Sponsors: Airport development. (a) To be eligible to apply for a project for airport development with...
Olney, Cynthia A.; Backus, Joyce E. B.; Klein, Lori J.
2010-01-01
Objectives: Through interviews with the National Library of Medicine's MedlinePlus Go Local collaborators, an evaluation team sought to identify process characteristics that are critical for long-term sustainability of Go Local projects and to describe the impact that Go Local projects have on sponsoring institutions. Methods: Go Local project coordinators (n = 44) at 31 sponsor institutions participated in semi-structured interviews about their experiences developing and maintaining Go Local sites. Interviews were summarized, checked for accuracy by the participating librarians, and analyzed using a general inductive methodology. Results: Institutional factors that support Go Local projects were identified through the interviews, as well as strategies for staffing and partnerships with external organizations. Positive outcomes for sponsoring institutions also were identified. Conclusions: The findings may influence the National Library of Medicine team's decisions about improvements to its Go Local system and the support it provides to sponsoring institutions. The findings may benefit current sponsoring institutions as well as those considering or planning a Go Local project. PMID:20098657
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-20
...://www.fda.gov/ScienceResearch/SpecialTopics/RunningClinicalTrials/ProposedRegulationsandDraftGuidances...] Draft Guidance for IRBs, Clinical Investigators, and Sponsors: IRB Responsibilities for Reviewing the... IRBs, Clinical Investigators, and Sponsors: IRB Responsibilities for Reviewing the Qualifications of...
UNION-SPONSORED RETRAINING PROGRAMS.
ERIC Educational Resources Information Center
HOOS, IDA R.
UNION-SPONSORED TRAINING PROGRAMS WERE PROVIDED IN THE SAN FRANCISCO BAY AREA TO UPGRADE SKILLS OF MARINE COOKS AND STEWARDS, SHIPS' RADIO OPERATORS, JOURNEYMAN PLUMBERS AND GASFITTERS, AND MEMBERS OF THE INTERNATIONAL BROTHERHOOD OF ELECTRICAL WORKERS (IBEW). THESE PROGRAMS WERE THE ONLY COHESIVE UNION SPONSORED CURRICULA IN THAT AREA. MAJOR…
Code of Federal Regulations, 2013 CFR
2013-07-01
... AND COMMAND SPONSORED FAMILY MEMBERS § 589.2 Policy. (a) This part (chapter) implements procedural... well as to their command sponsored family members. (b) DODD 5525.9 requires DoD cooperation with courts... DoD employees serving outside the United States, as well as their command sponsored family members...
Code of Federal Regulations, 2012 CFR
2012-07-01
... AND COMMAND SPONSORED FAMILY MEMBERS § 589.2 Policy. (a) This part (chapter) implements procedural... well as to their command sponsored family members. (b) DODD 5525.9 requires DoD cooperation with courts... DoD employees serving outside the United States, as well as their command sponsored family members...
Code of Federal Regulations, 2014 CFR
2014-07-01
... AND COMMAND SPONSORED FAMILY MEMBERS § 589.2 Policy. (a) This part (chapter) implements procedural... well as to their command sponsored family members. (b) DODD 5525.9 requires DoD cooperation with courts... DoD employees serving outside the United States, as well as their command sponsored family members...
48 CFR 35.017-1 - Sponsoring agreements.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Sponsoring agreements. 35... CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.017-1 Sponsoring agreements. (a) In order... mission, and ensure a periodic reevaluation of the FFRDC, a written agreement of sponsorship between the...
48 CFR 35.017-1 - Sponsoring agreements.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Sponsoring agreements. 35... CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.017-1 Sponsoring agreements. (a) In order... mission, and ensure a periodic reevaluation of the FFRDC, a written agreement of sponsorship between the...
48 CFR 35.017-1 - Sponsoring agreements.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Sponsoring agreements. 35... CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.017-1 Sponsoring agreements. (a) In order... mission, and ensure a periodic reevaluation of the FFRDC, a written agreement of sponsorship between the...
Student Tours--Who Is Watching Your Child?
ERIC Educational Resources Information Center
Holcomb, John H.
1983-01-01
Most parents do not recognize the difference between school-sponsored tours and those sponsored commercially, because both may be advertised through the schools. Parents considering tours for their children should look into the qualifications of the sponsoring organization and chaperones, provisions for medical care, and other matters. (PP)
14 CFR 151.37 - Sponsor eligibility.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Sponsor eligibility. 151.37 Section 151.37 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS... particular airport a sponsor must— (a) Be a public agency, which includes for the purposes of this part only...
14 CFR 151.37 - Sponsor eligibility.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Sponsor eligibility. 151.37 Section 151.37 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS... particular airport a sponsor must— (a) Be a public agency, which includes for the purposes of this part only...
The Sponsors of Literacy. Report Series 7.12.
ERIC Educational Resources Information Center
Brandt, Deborah
Intuitively, "sponsors" seems a fitting term for the figures who turned up most typically in people's memories of literacy learning: older relatives, teachers, priests, supervisors, military officers, editors, influential authors. The concept of sponsors helps to explain a range of human relationships and ideological pressures that turn…
An Experimental Study of Water Injection into a Rolls-Royce Model 250-C20B Turboshaft Gas Turbine
2008-05-06
0704-0188), Washington, DC 20503. 1. AGENCY USE ONLY (Leave blank) 2. REPORT DATE 6 May 2008 3. REPORT TYPE AND DATE COVERED 4...9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSORING/MONITORING AGENCY REPORT NUMBER US Naval Academy... used an instrumented Model 250-C20B gas turbine and an original water spray system. Temperatures and pressures were measured for each of the gas
Advanced 3D Printers for Cellular Solids
2016-06-30
2211 3d printing , cellular solids REPORT DOCUMENTATION PAGE 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 10. SPONSOR/MONITOR’S ACRONYM(S) ARO 8...quality 3D printing and rapid prototyping in a fraction of the time taken by traditional 3D printers, using eco-friendly, inexpensive office paper and...STL file, which then can be used in printing the 3D model. Mechanical performance using compressive crushing of the 3D printed part will be studied
2006-08-05
ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) AF Office of Scientific h Researc 875 N. Randolph St. Room 3112 11. SPONSOR/MONITOR’S REPORT...the process is often time-consuming and expensive. As the IMU market is experiencing a migration trend towards Micro Electro-Mechanical System (MEMS
Benign Breast Disease: Toward Molecular Prediction of Breast Cancer Risk
2004-06-01
stored in groups according to immunostain (i.e., all of the number 3 slides together, the number 4 slides, and so on) to match the stain in bar coded...standoff between the DOD and Wayne State on consent form language around institutional coverage for any "research- related risks". Dr. Beitens from the...Sponsoring this Study Clinic will not be jeopardized. This work has been, and continues to be, sponsored by several groups including the Confidentiality
2016-12-01
Nonfederal Sponsors Why GAO Did This Study Through its Civil Works program, the Corps designs , constructs, and maintains federal water resources...Public Works United States Senate Dear Mr. Chairman: The U.S. Army Corps of Engineers (Corps) is the world’s largest public engineering, design ...its Civil Works Program, in general, the Corps plans, designs , constructs, operates, and maintains a wide range of water resources projects. Congress
2016-02-05
diode laser, Raman spectroscopy REPORT DOCUMENTATION PAGE 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 10. SPONSOR/MONITOR’S ACRONYM(S) ARO 8...this project supported the acquisition of a closed-cycle optical cryostat from Montana Instruments, as well as a new 785 nm diode laser and ultrahigh...planned experiments on inelastic electron tunneling spectroscopy that require TɝK for optimal resolution. Additionally, the spatial position of
2008-04-01
a recommendation to the Phase I Sponsor, the NAVSEA SBIR Program Manager, and the PCO between 90 and 180 days after Phase I contract execution...determine eligibility for Phase II and send recommendations to sponsor Between 90 and 180 days after contract execution PCO Invites Phase II Proposals...manning study to evaluate the claim of inadequate numbers of contracting personnel. Although there were symptoms that contract delays were in part
2009-03-01
prevention and cessation among youth. A preliminary study was conducted using a pretest - posttest cohort design with assessments at baseline, 7 days and 6...TYPE OF REPORT: Annual PREPARED FOR: U.S. Army Medical Research and Materiel Command Fort Detrick...ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 11. SPONSOR/MONITOR’S
NASA Technical Reports Server (NTRS)
Wollan, M. J.
1975-01-01
The ability was examined of governmental agencies to adequately assess technological programs or projects to which they are committed. The hazards of government-sponsored activities are discussed; these include weather modification, supersonic transport noise, and the value conflicts involved in the fluoridation controversy. These three case studies indicate that the Federal vested interests in the continuation of its technological programs limit its ability to provide adequate technology assessment.
2008-11-07
CAPE CANAVERAL, Fla. -- In Building 1555 at Vandenberg Air Force Base in California, ssembly is underway for the Taurus XL rocket that will launch NASA's Orbiting Carbon Observatory, or OCO, spacecraft. Lined up left to right are the Stage 1 and Stage 2 motors, the boattail, the avionics shelf and the Stage 3 motor. The graphite/epoxy boattail structure provides the transition from the smaller diameter of the Stage 2 motor to the larger diameter of the avionics skirt. The avionics skirt, also a graphite/epoxy structure, supports the avionics shelf and carries the primary structural loads from the fairing and payload cone. The aluminum avionics shelf supports the third stage avionics. The OCO is a new Earth-orbiting mission sponsored by NASA's Earth System Science Pathfinder Program. The launch of OCO is targeted for January. Photo credit: NASA/Randy Beaudoin, VAFB
NASA Technical Reports Server (NTRS)
1977-01-01
The operation of mechanical and thermal strippers and the early development of laser wire strippers are reviewed. NASA sponsored development of laser wire stripping for space shuttle includes bench-type strippers as well as an advanced portable hand-held stripper which incorporates a miniaturized carbon dioxide laser and a rotating optics unit with a gas-jet assist and debris exhaust. Drives and controls girdle the wire and slit the remaining slug without manual assistance. This unit can strip wire sizes 26 through 12 gage. A larger-capacity hand-held unit for wire sizes through 1/0 gage was built using a neodynium-doped yttrium aluminum garnet (Nd:YAG) laser. The hand-held units have a flexible umbilical cable to an accompanying cart that carries the power supply, gas supply, cooling unit, and the controls.
Fabricating micro-instruments in surface-micromachined polycrystalline silicon
DOE Office of Scientific and Technical Information (OSTI.GOV)
Comtois, J.H.; Michalicek, M.A.; Barron, C.C.
1997-04-01
Smaller, lighter instruments can be fabricated as Micro-Electro-Mechanical Systems (MEMS), having micron scale moving parts packaged together with associated control and measurement electronics. Batch fabrication of these devices will make economical applications such as condition-based machine maintenance and remote sensing. The choice of instrumentation is limited only by the designer`s imagination. This paper presents one genre of MEMS fabrication, surface-micromachined polycrystalline silicon (polysilicon). Two currently available but slightly different polysilicon processes are presented. One is the ARPA-sponsored ``Multi-User MEMS ProcesS`` (MUMPS), available commercially through MCNC; the other is the Sandia National Laboratories ``Sandia Ultra-planar Multilevel MEMS Technology`` (SUMMiT). Example componentsmore » created in both processes will be presented, with an emphasis on actuators, actuator force testing instruments, and incorporating actuators into larger instruments.« less
A probabilistic assessment of health risks associated with short-term exposure to tropospheric ozone
DOE Office of Scientific and Technical Information (OSTI.GOV)
Whitfield, R.G; Biller, W.F.; Jusko, M.J.
1996-06-01
The work described in this report is part of a larger risk assessment sponsored by the U.S. Environmental Protection Agency. Earlier efforts developed exposure-response relationships for acute health effects among populations engaged in heavy exertion. Those efforts also developed a probabilistic national ambient air quality standards exposure model and a general methodology for integrating probabilistic exposure-response relation- ships and exposure estimates to calculate overall risk results. Recently published data make it possible to model additional health endpoints (for exposure at moderate exertion), including hospital admissions. New air quality and exposure estimates for alternative national ambient air quality standards for ozonemore » are combined with exposure-response models to produce the risk results for hospital admissions and acute health effects. Sample results explain the methodology and introduce risk output formats.« less
Strategic Planning for Health Care Cost Controls in a Constantly Changing Environment.
Hembree, William E
2015-01-01
Health care cost increases are showing a resurgence. Despite recent years' comparatively modest increases, the projections for 2015 cost increases range from 6.6% to 7%--three to four times larger than 2015's expected underlying inflation. This resurgence is just one of many rapidly changing external and internal challenges health plan sponsors must overcome (and this resurgence advances the date when the majority of employers will trigger the "Cadillac tax"). What's needed is a planning approach that is effective in overcoming all known and yet-to-be-discovered challenges, not just affordability. This article provides detailed guidance in adopting six proven strategic planning steps. Following these steps will proactively and effectively create a flexible strategic plan for the present and future of employers' health plans that will withstand all internal and external challenges.
The Third Annual NASA Science Internet User Working Group Conference
NASA Technical Reports Server (NTRS)
Lev, Brian S. (Editor); Gary, J. Patrick (Editor)
1993-01-01
The NASA Science Internet (NSI) User Support Office (USO) sponsored the Third Annual NSI User Working Group (NSIUWG) Conference March 30 through April 3, 1992, in Greenbelt, MD. Approximately 130 NSI users attended to learn more about the NSI, hear from projects which use NSI, and receive updates about new networking technologies and services. This report contains material relevant to the conference; copies of the agenda, meeting summaries, presentations, and descriptions of exhibitors. Plenary sessions featured a variety of speakers, including NSI project management, scientists, and NSI user project managers whose projects and applications effectively use NSI, and notable citizens of the larger Internet community. The conference also included exhibits of advanced networking applications; tutorials on internetworking, computer security, and networking technologies; and user subgroup meetings on the future direction of the conference, networking, and user services and applications.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hickman, R.; Anspaugh, L.
1985-04-01
FEMA has broad roles in the management of disasters potentially involving substantial amounts of radioactive contamination. These could be either peacetime or wartime disasters. A meeting was held in March 1985 to see if there are any research contributions that FEMA might reasonably make in the area of radioprotective drugs that would substantially enhance its ability to perform its mission. The other federal agencies presently sponsoring research in the field were represented at the meeting. A few selected researchers also participated to provide complementary viewpoints. Activities of a modest scale that FEMA might undertake were identified, as were larger scalemore » activities that might be undertaken in the event of long-term, major funding-level increases for FEMA. 2 refs.« less
14 CFR 151.51 - Performance of construction work: Sponsor force account.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Performance of construction work: Sponsor force account. 151.51 Section 151.51 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT... Development Projects § 151.51 Performance of construction work: Sponsor force account. (a) Before undertaking...
14 CFR 151.51 - Performance of construction work: Sponsor force account.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Performance of construction work: Sponsor force account. 151.51 Section 151.51 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT... Development Projects § 151.51 Performance of construction work: Sponsor force account. (a) Before undertaking...
14 CFR 151.51 - Performance of construction work: Sponsor force account.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Performance of construction work: Sponsor force account. 151.51 Section 151.51 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT... Development Projects § 151.51 Performance of construction work: Sponsor force account. (a) Before undertaking...
14 CFR 151.51 - Performance of construction work: Sponsor force account.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Performance of construction work: Sponsor force account. 151.51 Section 151.51 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT... Development Projects § 151.51 Performance of construction work: Sponsor force account. (a) Before undertaking...
14 CFR 151.51 - Performance of construction work: Sponsor force account.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Performance of construction work: Sponsor force account. 151.51 Section 151.51 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT... Development Projects § 151.51 Performance of construction work: Sponsor force account. (a) Before undertaking...
42 CFR 440.350 - Employer-sponsored insurance health plans.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 42 Public Health 4 2014-10-01 2014-10-01 false Employer-sponsored insurance health plans. 440.350 Section 440.350 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... Benchmark-Equivalent Coverage § 440.350 Employer-sponsored insurance health plans. (a) A State may provide...
42 CFR 440.350 - Employer-sponsored insurance health plans.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 42 Public Health 4 2012-10-01 2012-10-01 false Employer-sponsored insurance health plans. 440.350 Section 440.350 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... Benchmark-Equivalent Coverage § 440.350 Employer-sponsored insurance health plans. (a) A State may provide...
42 CFR 423.584 - Expediting certain redeterminations.
Code of Federal Regulations, 2010 CFR
2010-10-01
...). The 7 calendar day period begins the day the Part D plan sponsor receives the request for expedited... prescriber may request that a Part D plan sponsor expedite a redetermination that involves the issues... directly to the Part D plan sponsor or, if applicable, to the entity responsible for making the...
7 CFR 226.12 - Administrative payments to sponsoring organizations for day care homes.
Code of Federal Regulations, 2012 CFR
2012-01-01
... (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS CHILD AND ADULT... organization's budget, or (3) the sum of the products obtained by multiplying each month the sponsoring... administrative budget detailing the costs which the sponsoring organization shall incur, document, and claim...
7 CFR 226.12 - Administrative payments to sponsoring organizations for day care homes.
Code of Federal Regulations, 2013 CFR
2013-01-01
... (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS CHILD AND ADULT... organization's budget, or (3) the sum of the products obtained by multiplying each month the sponsoring... administrative budget detailing the costs which the sponsoring organization shall incur, document, and claim...
7 CFR 226.12 - Administrative payments to sponsoring organizations for day care homes.
Code of Federal Regulations, 2014 CFR
2014-01-01
... (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS CHILD AND ADULT... organization's budget, or (3) the sum of the products obtained by multiplying each month the sponsoring... administrative budget detailing the costs which the sponsoring organization shall incur, document, and claim...
7 CFR 226.12 - Administrative payments to sponsoring organizations for day care homes.
Code of Federal Regulations, 2010 CFR
2010-01-01
... (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS CHILD AND ADULT... organization's budget, or (3) the sum of the products obtained by multiplying each month the sponsoring... administrative budget detailing the costs which the sponsoring organization shall incur, document, and claim...
7 CFR 226.12 - Administrative payments to sponsoring organizations for day care homes.
Code of Federal Regulations, 2011 CFR
2011-01-01
... (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS CHILD AND ADULT... organization's budget, or (3) the sum of the products obtained by multiplying each month the sponsoring... administrative budget detailing the costs which the sponsoring organization shall incur, document, and claim...
14 CFR 152.105 - Sponsors and planning agencies: Airport planning.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Sponsors and planning agencies: Airport... TRANSPORTATION (CONTINUED) AIRPORTS AIRPORT AID PROGRAM Eligibility Requirements and Application Procedures § 152.105 Sponsors and planning agencies: Airport planning. (a) To be eligible to apply for a project for...
14 CFR 152.105 - Sponsors and planning agencies: Airport planning.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Sponsors and planning agencies: Airport... TRANSPORTATION (CONTINUED) AIRPORTS AIRPORT AID PROGRAM Eligibility Requirements and Application Procedures § 152.105 Sponsors and planning agencies: Airport planning. (a) To be eligible to apply for a project for...
14 CFR 152.105 - Sponsors and planning agencies: Airport planning.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Sponsors and planning agencies: Airport... TRANSPORTATION (CONTINUED) AIRPORTS AIRPORT AID PROGRAM Eligibility Requirements and Application Procedures § 152.105 Sponsors and planning agencies: Airport planning. (a) To be eligible to apply for a project for...
14 CFR 152.105 - Sponsors and planning agencies: Airport planning.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Sponsors and planning agencies: Airport... TRANSPORTATION (CONTINUED) AIRPORTS AIRPORT AID PROGRAM Eligibility Requirements and Application Procedures § 152.105 Sponsors and planning agencies: Airport planning. (a) To be eligible to apply for a project for...
14 CFR 152.105 - Sponsors and planning agencies: Airport planning.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Sponsors and planning agencies: Airport planning. 152.105 Section 152.105 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF....105 Sponsors and planning agencies: Airport planning. (a) To be eligible to apply for a project for...
AGU Sponsors Two Congressional Science Fellows
NASA Astrophysics Data System (ADS)
Chell, Kaitlin
2010-06-01
AGU will sponsor not one, but two Congressional Science Fellows (CSF) for the 2010-2011 fellowship term. Beginning in September, Jason Day and Ilya Fischhoff each will spend a year working in the congressional office of a U.S. senator or representative or in the office of a congressional committee. Both fellows were selected in March by AGU's Committee on Public Affairs after a competitive interview process. Their terms will mark the 33rd year AGU has sponsored a CSF and the first year AGU has ever sponsored two CSFs at one time.
The economic returns of pediatric clinical trials of anti-hypertensive drugs
Baker-Smith, Carissa M.; Benjamin, Daniel K.; Grabowski, Henry G.; Reid, Elizabeth D.; Mangum, Barry; Goldsmith, John V.; Murphy, M. Dianne; Edwards, Rex; Eisenstein, Eric L.; Sun, Jessica; Califf, Robert M.; Li, Jennifer S.
2012-01-01
Background Congress has authorized the U.S. Food and Drug Administration (FDA) to provide industry sponsors with a 6-month extension of drug marketing rights under the Pediatric Exclusivity Provision if FDA-requested pediatric drug trials are conducted. The cost and economic return of pediatric exclusivity to industry sponsors has been shown to be highly variable. We sought to determine the cost of performing pediatric exclusivity trials within a single therapeutic area and the subsequent economic return to industry sponsors. Methods We evaluated 9 orally administered anti-hypertensive drugs submitted to the FDA under the Pediatric Exclusivity Provision from 1997–2004 and obtained key elements of the clinical trial designs and operations. Estimates of the costs of performing the studies were generated and converted into after-tax cash outflow. Market sales were obtained and converted into after-tax inflows based on 6 months of additional patent protection. Net economic return and net return-to-cost ratios were determined for each drug. Results Of the 9 anti-hypertensive agents studied, an average of 2 studies per drug was performed, including at least 1 pharmacokinetic study and a safety and efficacy study. The median cost of completing a pharmacokinetic trial was $862,000 (range: $556,000–1.8 million). The median cost of performing safety and efficacy trials for these agents was $4.3 million (range: $2.1 million–12.9 million). The ratio of net economic return to cost was 17 (range: 4–64.7). Conclusion We found that, within a cohort of anti-hypertensive drugs, the Pediatric Exclusivity Provision has generated highly variable, yet lucrative returns to industry sponsors. PMID:18926149
The effect of funding sources on donepezil randomised controlled trial outcome: a meta-analysis.
Killin, Lewis O J; Russ, Tom C; Starr, John M; Abrahams, Sharon; Della Sala, Sergio
2014-04-07
To investigate whether there is a difference in the treatment effect of donepezil on cognition in Alzheimer disease between industry-funded and independent randomised controlled trials. Fixed effects meta-analysis of standardised effects of donepezil on cognition as measured by the Mini Mental State Examination and the Alzheimer's Disease Assessment Scale-cognitive subscale. Studies included in the meta-analyses reported in the National Institute for Health and Care Excellence (NICE) technical appraisal 217 updated with new studies through a PubMed search. Inclusion criteria were double-blind, placebo-controlled trials of any length comparing patients diagnosed with probable Alzheimer disease (according to the NINCDS-ADRDA/DSM-III/IV criteria) taking any dosage of donepezil. Studies of combination therapies (eg, donepezil and memantine) were excluded, as were studies that enrolled patients with a diagnosis of Alzheimer disease associated with other disorders (eg, Parkinson's disease and Down's syndrome). Our search strategy identified 14 relevant trials (4 independent) with suitable data. Trials sponsored by pharmaceutical companies reported a larger effect of donepezil on standardised cognitive tests than trials published by independent research groups (standardised mean difference (SMD)=0.46, 95% CI 0.37 to 0.55 vs SMD=0.33, 95% CI 0.18 to 0.48, respectively). This difference remained when only data representing change up to 12 weeks from baseline were analysed (industry SMD=0.44, 95% CI 0.34 to 0.53 vs independent SMD=0.35, 95% CI 0.18 to 0.52). Analysis revealed that the effect of funding as a moderator variable of study heterogeneity was not statistically significant at either time point. The effect size of donepezil on cognition is larger in industry-funded than independent trials and this is not explained by the longer duration of industry-funded trials. The lack of a statistically significant moderator effect may indicate that the differences are due to chance, but may also result from lack of power.
EAP viewpoint on unpublished data from paediatric clinical trials.
Schrier, L; Illy, K; Valiulis, A; Wyder, C; Stiris, T
2018-02-01
European children and paediatricians rely heavily on the fair, complete and timely publication of data obtained from paediatric randomised controlled trials (RCTs). Selective publication and reporting of paediatric RCTs is common practice. Industry-sponsored trials are more likely to remain unpublished, and take longer to get published compared with trials sponsored by others. However, also academic sponsors contribute to inefficiencies in publishing clinical data. Publication bias violates the ethical obligation that investigators have towards study participants, leads to considerable inefficiencies in research and a waste of financial and human resources, and has the potential to distort evidence for treatment approaches. The European Academy of Paediatrics (EAP) therefore actively supports initiatives that increase the public dissemination of paediatric clinical trial data. The EAP will raise awareness about the guidelines for Good Publication Practice among European paediatricians and subspecialty societies.
Effects of Disclosing Sponsored Content in Blogs
van Reijmersdal, Eva A.; Fransen, Marieke L.; van Noort, Guda; Opree, Suzanna J.; Vandeberg, Lisa; Reusch, Sanne; van Lieshout, Floor; Boerman, Sophie C.
2016-01-01
This article presents two studies examining the effects of disclosing online native advertising (i.e., sponsored content in blogs) on people’s brand attitude and purchase intentions. To investigate the mechanisms underlying these effects, we integrated resistance theories with the persuasion knowledge model. We theorize that disclosures activate people’s persuasion knowledge, which in turn evokes resistance strategies that people use to cope with the persuasion attempt made in the blog. We tested our predications with two experiments (N = 118 and N = 134). We found that participants indeed activated persuasion knowledge in response to disclosures, after which they used both cognitive (counterarguing) and affective (negative affect) resistance strategies to decrease persuasion. The obtained insights do not only advance our theoretical understanding of how disclosures of sponsored blogs affect persuasion but also provide valuable insights for legislators, advertisers, and bloggers. PMID:27721511
The Military Health Care System May Have the Potential to Prevent Health Care Disparities.
Pierre-Louis, Bosny J; Moore, Angelo D; Hamilton, Jill B
2015-09-01
The existence of health disparities in military populations has become an important topic of research. However, to our knowledge, this is the first study to examine health disparities, as related to access to care and health status, among active duty soldiers and their families. Specifically, the purpose of this analysis was to evaluate whether health disparities exist in access to care and health outcomes of patient satisfaction, physical health status, and mental health status according to race, gender, and sponsor rank in the population of active duty soldiers and their family members. In this cross-sectional study, active duty army soldiers and family members were recruited from either one particular army health clinic where they received their health care or from an adjacent shopping center frequented by eligible participants. Data were collected using validated measures to assess concepts of access to care and health status. Statistical analysis, including one-way analysis of variance (ANOVA) was performed to investigate differences in study outcome measures across four key demographic subgroups: race, gender, sponsor rank, and component (active soldier or family member). A total of 200 participants completed the study questionnaires. The sample consisted of 45.5 % soldiers and 54.5 % family members, with 88.5 % reporting a sponsor rank in the category of junior or senior enlisted rank. Mean scores for access to care did not differ significantly for the groups race/ethnicity (p = 0.53), gender (p = 0.14), and sponsor rank (p = 0.10). Furthermore, no significant differences were observed whether respondents were active soldiers or their family members (p = 0.36). Similarly, there were no statistically significant subgroup (race/ethnicity, gender, sponsor rank, or component) differences in mean patient satisfaction, physical health, and mental health scores. In a health equity system of care such as the military health care system, active duty soldiers and their family members did not experience disparities in access to care or in important health outcomes of patient satisfaction, physical health status, or mental health status.
Are All Clinical Studies Sponsored by Industry Not Valid?
Heinemann, Lutz
2008-01-01
Industry-sponsored studies have such a bad reputation that some journals require an additional statistical analysis by an independent statistician. This commentary discusses some of the reasons why academic people tend to believe that “academic” science is better than industry-driven science. Most likely, when it comes to publications, the risk of fraud exists in both worlds as the pressure to publish “significant” data is prevalent in both worlds. In contrast to the academic world, the level of control by regulatory bodies for industry-sponsored studies is much higher. Therefore, the quality of industry-driven studies is high, at least when it comes to the quality of data. One of the main reasons why academic people are so skeptical about the pharmaceutical industry is a lack of knowledge about the work done in industry. It is as demanding and scientific as in other industries. In turn, many physicians working in the pharmaceutical industry have low self-esteem. Also, the pharmaceutical industry should improve its self-presentation adequately to get rid of its bad image. There is a clear need for more communication between both worlds in order to better understand the mutual difficulties and needs. PMID:19885307
Code of Federal Regulations, 2010 CFR
2010-10-01
... organization sponsor a Senior Companion project without Corporation funding? 2551.111 Section 2551.111 Public... SENIOR COMPANION PROGRAM Non-Corporation Funded SCP Projects § 2551.111 Under what conditions can an agency or organization sponsor a Senior Companion project without Corporation funding? An eligible agency...
42 CFR 423.509 - Termination of contract by CMS.
Code of Federal Regulations, 2013 CFR
2013-10-01
... plan in writing 90 days before the intended date of the termination. (ii) The Part D plan sponsor... sponsor; (B) The Part D plan sponsor experiences financial difficulties so severe that its ability to make...)(4) of this section. (ii) CMS notifies the MA organization in writing that its contract will be...
The Handbook of Funding Opportunities in the Field of TESOL.
ERIC Educational Resources Information Center
Stoynoff, Stephen; Camacho, Terry
The handbook is intended to help those engaged in teaching English to speakers of other languages (TESOL) identify and effectively pursue sponsored support for research and other professional activities. It consists of four chapters. The first is an introduction to the world of sponsored support. Major sponsors are profiled and strategies for…
20 CFR 416.1204 - Deeming of resources of the sponsor of an alien.
Code of Federal Regulations, 2014 CFR
2014-04-01
... alien. 416.1204 Section 416.1204 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL... of the sponsor of an alien. The resources of an alien who first applies for SSI benefits after September 30, 1980, are deemed to include the resources of the alien's sponsor for 3 years after the alien's...
20 CFR 416.1204 - Deeming of resources of the sponsor of an alien.
Code of Federal Regulations, 2011 CFR
2011-04-01
... alien. 416.1204 Section 416.1204 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL... of the sponsor of an alien. The resources of an alien who first applies for SSI benefits after September 30, 1980, are deemed to include the resources of the alien's sponsor for 3 years after the alien's...
7 CFR 225.12 - Claims against sponsors.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 4 2010-01-01 2010-01-01 false Claims against sponsors. 225.12 Section 225.12 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SUMMER FOOD SERVICE PROGRAM State Agency Provisions § 225.12 Claims against sponsors. (a) The State agency...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-07
... Levels and Moratorium on New Sponsor Applications for Summer Work Travel Program AGENCY: Department of State. ACTION: Notice Regarding the Summer Work Travel Program. SUMMARY: Effective January 1, 2012, the... moratorium on designation of new Summer Work Travel sponsor organizations. FOR FURTHER INFORMATION CONTACT...
25 CFR 67.6 - Application forms.
Code of Federal Regulations, 2011 CFR
2011-04-01
... application form is filed by a sponsor, the name and address of the sponsor and the sponsor's relationship to... 25 Indians 1 2011-04-01 2011-04-01 false Application forms. 67.6 Section 67.6 Indians BUREAU OF... SEMINOLE INDIANS OF FLORIDA § 67.6 Application forms. (a) Application forms to be filed by or for...
25 CFR 67.6 - Application forms.
Code of Federal Regulations, 2014 CFR
2014-04-01
... application form is filed by a sponsor, the name and address of the sponsor and the sponsor's relationship to... 25 Indians 1 2014-04-01 2014-04-01 false Application forms. 67.6 Section 67.6 Indians BUREAU OF... SEMINOLE INDIANS OF FLORIDA § 67.6 Application forms. (a) Application forms to be filed by or for...
25 CFR 67.6 - Application forms.
Code of Federal Regulations, 2012 CFR
2012-04-01
... application form is filed by a sponsor, the name and address of the sponsor and the sponsor's relationship to... 25 Indians 1 2012-04-01 2011-04-01 true Application forms. 67.6 Section 67.6 Indians BUREAU OF... SEMINOLE INDIANS OF FLORIDA § 67.6 Application forms. (a) Application forms to be filed by or for...
25 CFR 67.6 - Application forms.
Code of Federal Regulations, 2013 CFR
2013-04-01
... application form is filed by a sponsor, the name and address of the sponsor and the sponsor's relationship to... 25 Indians 1 2013-04-01 2013-04-01 false Application forms. 67.6 Section 67.6 Indians BUREAU OF... SEMINOLE INDIANS OF FLORIDA § 67.6 Application forms. (a) Application forms to be filed by or for...
Summer Food Service Program for Children. 1991 Sponsor's Handbook. (Revised Edition).
ERIC Educational Resources Information Center
Food and Nutrition Service (USDA), Washington, DC.
This handbook is a reference for sponsors of food service programs for children during school vacation periods. It is not applicable to academic year operations. Issues relating to planning a food service program are discussed. These include sponsor eligibility, the determination of the need of recipient children, requirements of kinds and amounts…
20 CFR 416.1204 - Deeming of resources of the sponsor of an alien.
Code of Federal Regulations, 2010 CFR
2010-04-01
... alien. 416.1204 Section 416.1204 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL... of the sponsor of an alien. The resources of an alien who first applies for SSI benefits after September 30, 1980, are deemed to include the resources of the alien's sponsor for 3 years after the alien's...
20 CFR 416.1204 - Deeming of resources of the sponsor of an alien.
Code of Federal Regulations, 2013 CFR
2013-04-01
... alien. 416.1204 Section 416.1204 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL... of the sponsor of an alien. The resources of an alien who first applies for SSI benefits after September 30, 1980, are deemed to include the resources of the alien's sponsor for 3 years after the alien's...
20 CFR 416.1204 - Deeming of resources of the sponsor of an alien.
Code of Federal Regulations, 2012 CFR
2012-04-01
... alien. 416.1204 Section 416.1204 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL... of the sponsor of an alien. The resources of an alien who first applies for SSI benefits after September 30, 1980, are deemed to include the resources of the alien's sponsor for 3 years after the alien's...
14 CFR 151.113 - Advance planning proposals: Sponsor eligibility.
Code of Federal Regulations, 2012 CFR
2012-01-01
... Engineering Proposals § 151.113 Advance planning proposals: Sponsor eligibility. The sponsor of an advance planning and engineering proposal must be a public agency, as defined in § 151.37(a), and must be legally... agreement; (c) Provide enough funds to pay all estimated proposal costs not borne by the United States; and...
14 CFR 151.113 - Advance planning proposals: Sponsor eligibility.
Code of Federal Regulations, 2010 CFR
2010-01-01
... Engineering Proposals § 151.113 Advance planning proposals: Sponsor eligibility. The sponsor of an advance planning and engineering proposal must be a public agency, as defined in § 151.37(a), and must be legally... agreement; (c) Provide enough funds to pay all estimated proposal costs not borne by the United States; and...
2000-12-01
8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10 . SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR...Activities................................................................................ 48 10 . NIMA and Its Suppliers...Agency (DIA), the National Reconnaissance Office (NRO), the Defense Airborne Reconnaissance Office (DARO), and the Central Intelligence Agency” ibid. 10
76 FR 79064 - New Animal Drugs; Change of Sponsor; Zinc Gluconate
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-21
... [Docket No. FDA-2011-N-0003] New Animal Drugs; Change of Sponsor; Zinc Gluconate AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations to reflect a change of sponsor for a new animal drug application (NADA) for zinc...
76 FR 40229 - Oral Dosage Form New Animal Drugs; Change of Sponsor
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-08
.... FDA-2011-N-0003] Oral Dosage Form New Animal Drugs; Change of Sponsor AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations to reflect a change of sponsor for a new animal drug application (NADA) from Virbac AH...
75 FR 66304 - New Animal Drugs; Change of Sponsor; Monensin Blocks
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-28
... [Docket No. FDA-2010-N-0002] New Animal Drugs; Change of Sponsor; Monensin Blocks AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal... animal drug regulations as a sponsor of an approved application. Accordingly, Sec. 510.600 is being...
29 CFR 4043.29 - Change in contributing sponsor or controlled group.
Code of Federal Regulations, 2010 CFR
2010-07-01
... the plan's contributing sponsor before the effective date of the transaction is a public company, 30... the structure of Company Q's controlled group. On the effective date of the sale, Company R will... become effective, Company Q has the reporting obligation. If the change in the contributing sponsor has...
Code of Federal Regulations, 2014 CFR
2014-04-01
... registered under the Act as an associated person of that sponsoring futures commission merchant, retail... capacity of an associated person of such sponsor upon filing by that sponsor with the National Futures... which the associated person is associated. (2) Upon receipt by the National Futures Association of a...
7 CFR 226.13 - Food service payments to sponsoring organizations for day care homes.
Code of Federal Regulations, 2010 CFR
2010-01-01
... day care homes. 226.13 Section 226.13 Agriculture Regulations of the Department of Agriculture... CARE FOOD PROGRAM Payment Provisions § 226.13 Food service payments to sponsoring organizations for day care homes. (a) Payments shall be made only to sponsoring organizations operating under an agreement...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-30
... 558 [Docket No. FDA-2012-N-0002] New Animal Drugs; Change of Sponsor; Estradiol; Estradiol Benzoate.... ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations to reflect a change of sponsor for 17 new animal drug applications (NADAs) and abbreviated new...
22 CFR 62.76 - Transfer procedures.
Code of Federal Regulations, 2012 CFR
2012-04-01
... at a time specified by the transfer sponsor, and shall provide updated U.S. address information. (v... sponsor in a manner and at a time specified by the transfer sponsor and shall provide updated U.S. address... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Transfer procedures. 62.76 Section 62.76...
22 CFR 62.76 - Transfer procedures.
Code of Federal Regulations, 2011 CFR
2011-04-01
... at a time specified by the transfer sponsor, and shall provide updated U.S. address information. (v... sponsor in a manner and at a time specified by the transfer sponsor and shall provide updated U.S. address... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Transfer procedures. 62.76 Section 62.76...
22 CFR 62.76 - Transfer procedures.
Code of Federal Regulations, 2013 CFR
2013-04-01
... at a time specified by the transfer sponsor, and shall provide updated U.S. address information. (v... sponsor in a manner and at a time specified by the transfer sponsor and shall provide updated U.S. address... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Transfer procedures. 62.76 Section 62.76...
22 CFR 62.76 - Transfer procedures.
Code of Federal Regulations, 2010 CFR
2010-04-01
... at a time specified by the transfer sponsor, and shall provide updated U.S. address information. (v... sponsor in a manner and at a time specified by the transfer sponsor and shall provide updated U.S. address... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Transfer procedures. 62.76 Section 62.76...
22 CFR 62.76 - Transfer procedures.
Code of Federal Regulations, 2014 CFR
2014-04-01
... at a time specified by the transfer sponsor, and shall provide updated U.S. address information. (v... sponsor in a manner and at a time specified by the transfer sponsor and shall provide updated U.S. address... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Transfer procedures. 62.76 Section 62.76...
A Guide to Community Shared Solar: Utility, Private, and Non-Profit Project Development (Book)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Coughlin, J.; Grove, J.; Irvine, L.
2012-05-01
This guide is organized around three sponsorship models: utility-sponsored projects, projects sponsored by special purpose entities - businesses formed for the purpose of producing community solar power, and non-profit sponsored projects. The guide addresses issues common to all project models, as well as issues unique to each model.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-19
...-7001 and DS- 7005, DOS-Sponsored Academic Exchange Program Application, OMB Control Number 1405-0138.... Title of Information Collection: DOS-Sponsored Academic Exchange Program Application. OMB Control Number... Academic Exchange Program. Estimated Number of Respondents: 7160 (For DS-7001, 3842 estimated; for DS-7005...
Domain Processes in Ferroelectric Ceramics
1994-04-14
elastic strain tensor and eikl is the Levi - Civita density. Eqs (11) and (12) has three nontrivial solutions: Xr3 = 0 (13) Xr"= -1 { [ 2sj2Q 12 -Sl I...ABSTRACT (aA~iMUM 200 wardt) This report Outlines the progres achieved during a two year effort sponsored by the AFOSR on the theoretical study of domain...INTRODUCTION This is the final progress report for this two year program sponsored by the Air Force Office of Scientific Research on "Domain Processes in
2017-11-01
University of Maryland Baltimore, MD 21202 DATE OF REPORT: November 2017 TYPE OF REPORT: Final PREPARED FOR: U.S. Army Medical Research and Materiel...ES) 10. SPONSOR/MONITOR’S ACRONYM(S) U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5014 11. SPONSOR/MONITOR’S REPORT...Prytime Medical , Boerne, TX )) in October 2015, we incorporated this catheter into our practice in February 2016. Our REBOA training course (Basic
Synthetic Aperture Acoustic Imaging of Canonical Targets with a 2-15 kHz Linear FM Chirp
2011-04-25
PERFORMING ORGANIZATION NAMES AND ADDRESSES U.S. Army Research Office P.O. Box 12211 Research Triangle Park, NC 27709-2211 15. SUBJECT TERMS...55997-CS.1 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 10. SPONSOR/MONITOR’S ACRONYM(S) ARO 8. PERFORMING ORGANIZATION REPORT NUMBER 19a. NAME OF...targets (bowling ball and softball ) • on dirt and grass • behind a metallic chain link fence d. Material study • open and closed cell foam • ceiling
People’s War on the East Sea: Is Vietnam’s Theory of War Still Applicable
2017-05-25
wording in the document concerning islands gave rise to competing claims for salient low tide features that are not present during high tide.148...People’s War on the East Sea: Is Vietnam’s Theory of War Still Applicable? A Monograph by MAJ Chad D. Corbin US Army School of Advanced... School of Advanced Military Studies. 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION / AVAILABILITY
Navy Force Structure: Alternative Force Structure Studies of 2005 - Background for Congress
2007-04-09
multiple classes of a single ship [ type ] is another prudent way to enforce costs, since the DoN can divert production of any ship class that exceeds...not display a currently valid OMB control number. 1. REPORT DATE 09 APR 2007 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE...MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION/ AVAILABILITY
[Constraints on publication rights in industry-initiated clinical trials--secondary publication].
Gøtzsche, Peter C; Hróbjartsson, Asbjørn; Johansen, Helle Krogh; Haahr, Mette T; Altman, Douglas G; Chan, An-Wen
2006-06-19
In 22 of 44 industry-initiated clinical trial protocols from 1994-95, it was noted that the sponsor either owned the data or needed to approve the manuscript; another 18 protocols had other constraints. Furthermore, in 16 trials, the sponsor had access to accumulating data, and in an additional 16 trials the sponsor could stop the trial at any time, for any reason. These facts were not noted in any of the trial reports. We found similar constraints on publication rights in 44 protocols from 2004. This tight sponsor control over industry-initiated trials should be changed.
Kelly, Bridget; Baur, Louise A; Bauman, Adrian E; King, Lesley; Chapman, Kathy; Smith, Ben J
2013-01-01
To determine parents' and children's attitudes towards food, beverage and alcohol sponsorship of elite and children's sports and the acceptability of policies and alternative funding models to limit this sponsorship. Telephone surveys were conducted with parents in February-May 2011. One child from each household was invited to complete an online survey. Surveys assessed parents' perceptions about the influence of sponsorship on children and support for limiting sponsorship, and children's awareness of and attitudes towards sponsors. Randomly sampled households in New South Wales, Australia. Parents (n 825) and children aged 10–16 years (n = 243). Three-quarters of parents supported the introduction of policies to restrict unhealthy food, beverage and alcohol sponsorship of children's and elite sports. More parents (81 %) supported the introduction of alternative funding models to allow these companies to sponsor sport provided there was no visible branding. Two-thirds of children recalled sponsors of their favourite elite sports team/athlete, with 428 sponsors recalled. Of these, 11 % were food/beverage companies and 3 % were alcohol-related. For 39 % of sponsors, children reported feeling better about the company after it had sponsored a team/athlete. Australian parents support restrictions on unhealthy food, beverage and alcohol sport sponsorship. Children's positive associations regarding sponsors are likely to be linked to brand preferences and usage.
Jeong, Sohyun; Sohn, Minji; Kim, Jae Hyun; Ko, Minoh; Seo, Hee-Won; Song, Yun-Kyoung; Choi, Boyoon; Han, Nayoung; Na, Han-Sung; Lee, Jong Gu; Kim, In-Wha; Oh, Jung Mi; Lee, Euni
2017-06-21
Clinical trial globalization is a major trend for industry-sponsored clinical trials. There has been a shift in clinical trial sites towards emerging regions of Eastern Europe, Latin America, Asia, the Middle East, and Africa. Our study objectives were to evaluate the current characteristics of clinical trials and to find out the associated multiple factors which could explain clinical trial globalization and its implications for clinical trial globalization in 2011-2013. The data elements of "phase," "recruitment status," "type of sponsor," "age groups," and "design of trial" from 30 countries were extracted from the ClinicalTrials.gov website. Ten continental representative countries including the USA were selected and the design elements were compared to those of the USA. Factors associated with trial site distribution were chosen for a multilinear regression analysis. The USA, Germany, France, Canada, and United Kingdom were the "top five" countries which frequently held clinical trials. The design elements from nine continental representative countries were quite different from those of the USA; phase 1 trials were more prevalent in India (OR 1.517, p < 0.001) while phase 3 trials were much more prevalent in all nine representative countries than in the USA. A larger number of "child" age group trials was performed in Poland (OR 1.852, p < 0.001), Israel (OR 1.546, p = 0.005), and South Africa (OR 1.963, p < 0.001) than in the USA. Multivariate analysis showed that health care expenditure per capita, Economic Freedom Index, Human Capital Index, and Intellectual Property Rights Index could explain the variance of regional distribution of clinical trials by 63.6%. The globalization of clinical trials in the emerging regions of Asia, South Africa, and Eastern Europe developed in parallel with the factors of economic drive, population for recruitment, and regulatory constraints.
Interactions between physicians and the pharmaceutical industry: what does the literature say?
Lexchin, J
1993-01-01
OBJECTIVE: To determine the effect of three types of interaction between physicians and the pharmaceutical industry--company-funded clinical trials, company-sponsored continuing medical education (CME) and information for physicians supplied by pharmaceutical detailers--on orientation and quality of clinical trials, content of CME courses and physicians' prescribing behaviour. DATA SOURCES: MEDLINE and HEALTH searches for English-language articles published from 1978 to 1993, supplemented by material from the author's personal collection. STUDY SELECTION: A total of 227 papers from the MEDLINE and HEALTH searches and about 2000 items from the author's library were initially reviewed. The following selection criteria were used: studies conducted in Australia, Canada, New Zealand, Britain and the United States; studies conducted after 1977; quantitative surveys containing details of the survey methods; studies on the orientation and quality of company-funded clinical trials and on the content of CME courses giving explicit criteria used in the evaluation; and reports on the outcome of interactions stating how the outcomes were assessed. Thirty-six studies met these criteria. DATA EXTRACTION: Information was extracted on five topics: physicians' attitudes toward drug industry interactions, frequency with which physicians participate in the interactions, orientation and quality of company-funded clinical trials, content of company-sponsored CME courses and changes in physicians' prescribing behaviour as a result of an interaction. DATA SYNTHESIS: Although most physicians participate only occasionally in company-sponsored clinical trials, most see detailers and attend company-sponsored CME courses. However, physicians do not have a very high opinion of the information from detailers or of company-sponsored CME events. Many doctors regard pharmaceutical companies as an important source of funding for clinical trials, but they also have concerns about accepting money from this source. Company funding of clinical trials may affect the quality of the trials and the types of research that physicians undertake. Company-sponsored CME courses may have a commercial bias even if conducted under guidelines designed to ensure the independence of the event. All three types of interactions affect physicians' prescribing behaviour and, in the case of obtaining information from detailers, physicians' prescribing practices are less appropriate as a result of the interaction. CONCLUSIONS: Physicians are affected by their interactions with the pharmaceutical industry. Further research needs to be done in most cases to determine whether such interactions lead to more or less appropriate prescribing practices. The CMA's guidelines on this topic should be evaluated to see whether they are effective in controlling physician-industry interactions. Further measures may be necessary if the guidelines fail to prevent negative effects on prescribing practices. PMID:8221424
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-30
... Sponsor........ 15 8 120 0.33 39.6 Issuance Statement Attorney for Sponsor........ 15 8 120 0.5 60 Tax... Statements (attached to closing Accountant for Sponsor...... 15 8 120 32 3840 letter). Accountants' Closing Letter Accountant 15 8 120 8 960 Accountants' OCS Letter Accountant 15 8 120 8 960 Structuring Data...
ERIC Educational Resources Information Center
Center for Applied Linguistics, Washington, DC. Language and Orientation Resource Center.
An annotated bibliography of materials for the orientation of refugees and their sponsors is a supplement to "A Guide to Orientation Materials for Indochinese Refugees and their Sponsors," and includes 40 entries for materials pertinent to many other, non-Indochinese refugee groups. The materials are grouped alphabetically by the…
1992-12-28
Research Program Starfire Optical Range, Phillips Laboratory /LITE Kirtland Air Force Base, Albuquerque, NM 87117 Sponsored by: Air ... Phillips Laboratory Sponsored by: Air Force Office of Scientific Research Kirtland Air Force Base, Albuquerque, New Mexico September, 1992 18-1 PROGRESS...Report for: Summer Research Program Phillips Laboratory Sponsored by: Air
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-05
... and DS- 7005, DOS-Sponsored Academic Exchange Program Application, OMB Control Number 1405-0138 ACTION... Collection: DOS-Sponsored Academic Exchange Program Application. OMB Control Number: 1405-0138. Type of... Cultural Affairs, ECA/A/E/EUR. Form Number: DS-7001, DS-7005. Respondents: Applicants for the Academic...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-28
... proposes to amend the definition of Sponsored Participant as part of the instant proposed rule change. \\4... obtain authorized access by entering into and maintaining customer agreements with one or more Sponsoring Members \\7\\ through which the Sponsored Participant may trade on the Exchange's System.\\8\\ The customer...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-28
... proposes to amend the definition of Sponsored Participant as part of the instant proposed rule change. \\4... obtain authorized access by entering into and maintaining customer agreements with one or more Sponsoring Members \\7\\ through which the Sponsored Participant may trade on the Exchange's System.\\8\\ The customer...
78 FR 27859 - New Animal Drugs; Change of Sponsor's Name and Address; Change of Sponsor
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-13
... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Parts 510 and 558... Purina Mills, Inc., to Purina Nutrition LLC, and a change of sponsor for a new animal drug application (NADA) from Land O'Lakes Purina Feed LLC to Purina Nutrition LLC. The regulations are also being amended...
Code of Federal Regulations, 2013 CFR
2013-07-01
... state authorities for custody of an overseas civilian employee or a command-sponsored family member. 884... or a command-sponsored family member. (a) The procedures of this section apply to civilian employees..., and to command-sponsored family members residing outside the United States. (b) This section applies...
Code of Federal Regulations, 2012 CFR
2012-07-01
... state authorities for custody of an overseas civilian employee or a command-sponsored family member. 884... or a command-sponsored family member. (a) The procedures of this section apply to civilian employees..., and to command-sponsored family members residing outside the United States. (b) This section applies...
Code of Federal Regulations, 2014 CFR
2014-07-01
... state authorities for custody of an overseas civilian employee or a command-sponsored family member. 884... or a command-sponsored family member. (a) The procedures of this section apply to civilian employees..., and to command-sponsored family members residing outside the United States. (b) This section applies...
Code of Federal Regulations, 2011 CFR
2011-07-01
... state authorities for custody of an overseas civilian employee or a command-sponsored family member. 884... or a command-sponsored family member. (a) The procedures of this section apply to civilian employees..., and to command-sponsored family members residing outside the United States. (b) This section applies...
Code of Federal Regulations, 2010 CFR
2010-07-01
... state authorities for custody of an overseas civilian employee or a command-sponsored family member. 884... or a command-sponsored family member. (a) The procedures of this section apply to civilian employees..., and to command-sponsored family members residing outside the United States. (b) This section applies...
78 FR 69992 - Withdrawal of Approval of New Animal Drug Applications; Carbarsone; Roxarsone
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-22
...) * * * Combinations in Roxarsone in grams per ton grams per ton Indications for use Limitations Sponsor (i) [Reserved...) * * * Combinations in Roxarsone in grams per ton grams per ton Indications for use Limitations Sponsor (i) [Reserved... Roxarsone in grams per ton grams per ton Indications for use Limitations Sponsor (i) [Reserved] (ii) 22.7 to...
Code of Federal Regulations, 2011 CFR
2011-04-01
... 25 Indians 1 2011-04-01 2011-04-01 false Where can tribes get scholarships and tuition for Indian... tribes get scholarships and tuition for Indian LTAP-sponsored education and training? Tribes can get tuition and scholarship assistance for Indian LTAP-sponsored education and training from the following...
Code of Federal Regulations, 2013 CFR
2013-04-01
... 25 Indians 1 2013-04-01 2013-04-01 false Where can tribes get scholarships and tuition for Indian... tribes get scholarships and tuition for Indian LTAP-sponsored education and training? Tribes can get tuition and scholarship assistance for Indian LTAP-sponsored education and training from the following...
Code of Federal Regulations, 2010 CFR
2010-04-01
... 25 Indians 1 2010-04-01 2010-04-01 false Where can tribes get scholarships and tuition for Indian... tribes get scholarships and tuition for Indian LTAP-sponsored education and training? Tribes can get tuition and scholarship assistance for Indian LTAP-sponsored education and training from the following...
Code of Federal Regulations, 2012 CFR
2012-04-01
... 25 Indians 1 2012-04-01 2011-04-01 true Where can tribes get scholarships and tuition for Indian... tribes get scholarships and tuition for Indian LTAP-sponsored education and training? Tribes can get tuition and scholarship assistance for Indian LTAP-sponsored education and training from the following...
Code of Federal Regulations, 2014 CFR
2014-04-01
... 25 Indians 1 2014-04-01 2014-04-01 false Where can tribes get scholarships and tuition for Indian... tribes get scholarships and tuition for Indian LTAP-sponsored education and training? Tribes can get tuition and scholarship assistance for Indian LTAP-sponsored education and training from the following...
ERIC Educational Resources Information Center
Beasley, Kenneth L.; And Others
Designed as a standard reference and training resource for administrators and project managers, this handbook discusses how to plan, organize, and manage sponsored projects in any organizational setting. It provides detailed, how-to-do-it information and many resources for: negotiating grants, awards, and contracts; organizing a sponsored projects…
Code of Federal Regulations, 2010 CFR
2010-10-01
... 42 Public Health 3 2010-10-01 2010-10-01 false How a Part D plan sponsor must effectuate standard... How a Part D plan sponsor must effectuate standard redeterminations, reconsiderations, or decisions. (a) Reversals by the Part D plan sponsor—(1) Requests for benefits. If, on redetermination of a...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-08
.... Sponsor: Maine Chapter, Multiple Sclerosis Society. Date: August 21, 2010. Time: 11 am to 2 pm. Location... Sailboat Race. Sponsor: Maine Chapter, Multiple Sclerosis Society. Date: August 21, 2010. Time: 10 am to 4... Tugboat Muster. Event Type: Power Boat Race. Sponsor: Maine Chapter, National Multiple Sclerosis Society...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-24
...-0076] Agency Information Collection Activities: Sponsor's Notice of Change of Address, Form I-865...: Sponsor's Notice of Change of Address. (3) Agency form number, if any, and the applicable component of the.... During this 60-day period, USCIS will be evaluating whether to revise the Form I-865. Should USCIS decide...
Institutionalizing Entrepreneurship: A History of Sponsored Research at the University of Michigan
ERIC Educational Resources Information Center
DeGraff, Staney
2006-01-01
This paper examines the history of sponsored research and industrial relationships at the University of Michigan. For the purposes of this paper, sponsored research is defined as research performed by the university that is funded by an outside constituent. Although this paper covers events from the start of the twentieth century, it concentrates…
ERIC Educational Resources Information Center
Pike, Mark A.
2009-01-01
The Emmanuel Schools Foundation (ESF) has so far sponsored four schools in England. Beginning with Emmanuel College in Gateshead in 1990 (which remains a City Technology College) the Foundation sponsors the King's Academy in Middlesbrough, which opened in 2003, and Trinity Academy in Thorne near Doncaster, which opened in 2005. The Foundation's…
45 CFR 149.600 - Sponsor's duty to report data inaccuracies.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 45 Public Welfare 1 2013-10-01 2013-10-01 false Sponsor's duty to report data inaccuracies. 149.600 Section 149.600 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS REQUIREMENTS FOR THE EARLY RETIREE REINSURANCE PROGRAM Disclosure of Data Inaccuracies § 149.600 Sponsor's duty to report data...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-23
... Rutherford, NSW 2320, Injectable Anesthetic maintenance of Australia. for Cats and Dogs. anesthesia and for induction of anesthesia followed by maintenance with an inhalant anesthetic, in dogs and cats. [[Page 64716...) of this chapter. (c) Conditions of use in cats and dogs--(1) Amount--(i) Cats--(A) Induction of...
ERIC Educational Resources Information Center
Vinuales, Gema; Harris, Judy
2017-01-01
Students implemented social media campaigns to raise awareness and funds for nonprofit organizations. Teams in one section of the course worked on a designated client-sponsored project (CSP), while teams in another section chose their own nonprofit organizations. Although both the CSPs and non-CSPs were evaluated favorably, students who worked on…
Sports Sponsorships of Food and Nonalcoholic Beverages.
Bragg, Marie A; Miller, Alysa N; Roberto, Christina A; Sam, Rachel; Sarda, Vishnudas; Harris, Jennifer L; Brownell, Kelly D
2018-04-01
Food and nonalcoholic beverage companies spend millions of dollars on professional sports sponsorships, yet this form of marketing is understudied. These sponsorships are valuable marketing tools but prompt concerns when unhealthy products are associated with popular sports organizations, especially those viewed by youth. This descriptive study used Nielsen audience data to select 10 sports organizations with the most 2-17 year old viewers of 2015 televised events. Sponsors of these organizations were identified and assigned to product categories. We identified advertisements promoting food and/or nonalcoholic beverage sponsorships on television, YouTube, and sports organization Web sites from 2006 to 2016, and the number of YouTube advertisement views. The nutritional quality of advertised products was assessed. Youth watched telecasts associated with these sports organizations over 412 million times. These organizations had 44 food and/or nonalcoholic beverage sponsors (18.8% of sponsors), second to automotive sponsors ( n = 46). The National Football League had the most food and/or nonalcoholic beverage sponsors ( n = 10), followed by the National Hockey League ( n = 7) and Little League ( n = 7). We identified 273 advertisements that featured food and/or nonalcoholic beverage products 328 times and product logos 83 times (some advertisements showed multiple products). Seventy-six percent ( n = 132) of foods had unhealthy nutrition scores, and 52.4% ( n = 111) of nonalcoholic beverages were sugar-sweetened. YouTube sponsorship advertisements totaled 195.6 million views. Sports sponsorships are commonly used to market unhealthy food and nonalcoholic beverages, exposing millions of consumers to these advertisements. Copyright © 2018 by the American Academy of Pediatrics.
Rosenberg, Michael; Ferguson, Renee
2014-12-04
Health message sponsorship at community sport and arts events is an established component of a health promotion settings approach. Recent increases in commercial sponsorship of sport and community events has swelled competition for consumer attention and potentially reduced the impact of health message sponsorship. The purpose of this study was to evaluate awareness, understandings and behavioural intentions of health messages promoted at sponsored community sport and arts events. Interview and self-administered surveys were completed by 2259 adults attending one of 29 sport and arts events held in Western Australia between 2008 and 2013. The surveys measured participant awareness of the health message promoted at the event, as well as comprehension, acceptance and behavioural intention as a result of exposure to health messages. Awareness of the sponsored health message was 58% across all sponsored events, with high levels of comprehension (74%) and acceptance (92%) among those aware of the health message. Forming behavioural intentions was significantly related to the type of sponsored message promoted at the event, being female and over 40 years of age. Messages about sun protection and promoting mental health were the most likely to result in behavioural intention. Health message sponsorship, at least within a comprehensive sponsorship program, appears to remain an effective health promotion strategy for generating awareness and behavioural intention among people attending sport and arts events. Remaining relevant within a modern sponsorship environment appears closely aligned to selecting health messages that promote behavioural action relevant to the sponsored event that are also supported by broader health promotion campaigns.
Food and drink sponsorship of children's sport in Australia: who pays?
Kelly, Bridget; Baur, Louise A; Bauman, Adrian E; King, Lesley; Chapman, Kathy; Smith, Ben J
2011-06-01
The creation of health promoting sports clubs may support the promotion and adoption of healthy behaviours by children. Sponsorship is one aspect of clubs, with potential influence on clubs and their participants. In particular, sponsorship influences brand awareness and attitudes, so that the sponsorship of children's sport by unhealthy food companies may contribute to food preferences and poor eating habits. This study aimed to determine the nature and extent of food and beverage sponsorship of children's sport. Sports clubs (n = 108) for the nine most popular sports for children aged 5-14 were randomly sampled from three large geographical areas in Australia. A purpose-designed telephone questionnaire was developed to determine the extent of sponsorship. Experts from different fields were approached (n = 10) to generate a consensus on the elements of sponsors that are more/less health promoting. The survey response rate was 99%. Of the 347 sponsors identified, 17% were food or beverage companies. Fifty percent of food company sponsorship arrangements did not meet criteria for healthy sponsors. For most clubs, less than a quarter of their income came from sponsorship. A considerable proportion of clubs with food company sponsors had the company's signage on players' uniforms (53%), distributed rewards using the company's name (24%) or gave vouchers to players for the company's products (29%). Any restriction of unhealthy food and beverage company sponsorship of children's sport may not result in major funding difficulties for clubs, as this funding represents a relatively small proportion of their income base, even though it provides major promotional opportunities to sponsors.
How to get on board Space Station Freedom
NASA Technical Reports Server (NTRS)
Bartoe, John-David
1992-01-01
Space Station Freedom will accommodate researchers with interests in science, technology and commercial applications. NASA sponsors will be responsible for selecting the U.S. researchers for Space Station Freedom. The four NASA sponsors are: Office of Space Science and Applications (OSSA), Office of Aeronautics and Space Technology (OAST), Office of Commercial Programs (OCP), and the Office of Space Flight (OSF). The areas of research responsibility for each sponsor are presented. The researcher solicitation vehicles used by OSSA and OAST and the methodology for researchers seeking sponsorship from OCP and OSF as well as the pricing policy are discussed. Descriptions of flight planning, payload integration and operations functions are presented. Three categories of payloads and their respective payload integration times are discussed. Researchers are advised to contact a NASA sponsor and a source which lists the points of contact for the NASA sponsors is noted.
Davidson, Robert M; McNeer, J Frederick; Logan, Leanne; Higginbotham, Michael B; Anderson, Jerome; Blackshear, Joseph; Chu, Alan; Hettleman, Bruce; McGrew, Frank; Meesse, Roderick; O'Connor, Christopher; Schneider, Ricky; Wagner, Galen S
2006-02-01
The purpose of this report is to present a model of physicians in full-time clinical practice participating as investigators in multicenter clinical trials, sponsored by a pharmaceutical or medical device company. This gas-exchange substudy was conducted as a pilot study to establish the feasibility of the 10-member EXERcise testing group of the Duke University Cooperative Cardiovascular Society (EXERDUCCS) consortium to perform a complex multicenter trial using cardiopulmonary exercise testing. An active interchange of information was established involving the principal investigator for the substudy, a dedicated full-time project coordinator, a medical director of the overall EXERDUCCS network site, the project coordinator for the sponsor, and all the participating EXERDUCCS investigators and coordinators. The sponsor set as a goal of enrollment of 6 subjects per site, and 8 of the 10 sites met this goal. As a result of the successful enrollment and completion of the study and substudy by the EXERDUCCS sites, the sponsor subsequently increased the payment stipends to the sites to compensate for the extra work and expense incurred. This cooperative experience accomplished several goals: (1) it allowed a complex clinical trial to be successfully completed in a time frame which would not have been possible using only single unconnected sites; (2) it educated the physician-investigators (and their personnel) in exercise cardiopulmonary; and (3) it prepared the sites for future clinical trials involving this methodology.
Secure and Efficient Network Fault Localization
2012-02-27
ORGANIZATION NAME(S) AND ADDRESS (ES) Carnegie Mellon University,School of Computer Science,Computer Science Department,Pittsburgh,PA,15213 8. PERFORMING...ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS (ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT...efficiency than previously known protocols for fault localization. Our proposed fault localization protocols also address the security threats that
Code of Federal Regulations, 2011 CFR
2011-10-01
... submitted by potential Part D sponsors. 423.272 Section 423.272 Public Health CENTERS FOR MEDICARE... and negotiation of bid and approval of plans submitted by potential Part D sponsors. (a) Review and...) Substantial differences between bids—(i) General. CMS approves a bid only if it finds that the benefit package...
Code of Federal Regulations, 2010 CFR
2010-10-01
... submitted by potential Part D sponsors. 423.272 Section 423.272 Public Health CENTERS FOR MEDICARE... and negotiation of bid and approval of plans submitted by potential Part D sponsors. (a) Review and...) Substantial differences between bids—(i) General. CMS approves a bid only if it finds that the benefit package...
2013-09-01
ORGANIZATION REPORT NUMBER ARL-TR-6576 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11 . SPONSOR... 11 Figure 11 . Estimated angle-of-attack components history, projectile no.2... 11 Figure 12. Comparison of angle-of-attack component estimates, projectile no.2. ........................12 Figure 13. Total angle-of
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-07
... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Parts 510 and 522... 317, Miami, FL 33157. Accordingly, the Agency is amending the regulations in parts 510 and 522 (21 CFR parts 510 and 522) to reflect these changes. Following this change of sponsorship, Synerx Pharma, LLC...
ERIC Educational Resources Information Center
Miller, Thomas I.
1984-01-01
Evaluates the evidence supporting claims that employer-sponsored child care programs improve employee work behaviors and attitudes. Results indicated that assertions that employer-sponsored child care reduces workers' absenteeism or tardiness, or that it increases workers' productivity or job satisfaction are not supported by credible research.…
2016-07-01
ORGANIZATION REPORT NUMBER ARL-TR-7727 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10 . SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S...of 0.50-cal. FSP vs. AA7017 plate at 0° .......................................................................................................... 10 ... 10 List of Tables Table 1 Chemical composition, weight percent
1998-01-01
Performing Organization Name(s) and Address(es) U.S. Department of Labor Occupational Safety & Health Administration 200 Constitution Avenue Washington, DC...20210 Performing Organization Report Number OSHA 3071 Sponsoring/Monitoring Agency Name(s) and Address(es) Sponsor/Monitor’s Acronym(s) Sponsor...identifying existing or potential job hazards (both safety and health), and determining the best way to perform the job or to reduce or eliminate these
Moving the Force: Desert Storm and Beyond
1994-12-01
information, updated through secure satellite links, battlefield distribution can become seamless, not accidental. Without it, we are reduced to aimless...SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION ...AVAILABILITY STATEMENT Approved for public release; distribution unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT see report 15. SUBJECT TERMS 16
Marital status, spousal coverage, and the gender gap in employer-sponsored health insurance.
Buchmueller, T C
Not only do men who work full time earn more than women, but they are more likely to receive employer-sponsored health benefits. This paper provides evidence on the gender gap in employer-sponsored health insurance. The results indicate that the gap is driven largely by the tendency of married women to decline employer-sponsored insurance in favor of being covered through their husbands. Indeed, among single workers, women are more likely than men to be offered insurance. These findings call into question the conclusion made by previous researchers that employers discriminate against women in the provision of health insurance.
Medical Malpractice Reform and Employer-Sponsored Health Insurance Premiums
Morrisey, Michael A; Kilgore, Meredith L; Nelson, Leonard (Jack)
2008-01-01
Objective Tort reform may affect health insurance premiums both by reducing medical malpractice premiums and by reducing the extent of defensive medicine. The objective of this study is to estimate the effects of noneconomic damage caps on the premiums for employer-sponsored health insurance. Data Sources/Study Setting Employer premium data and plan/establishment characteristics were obtained from the 1999 through 2004 Kaiser/HRET Employer Health Insurance Surveys. Damage caps were obtained and dated based on state annotated codes, statutes, and judicial decisions. Study Design Fixed effects regression models were run to estimate the effects of the size of inflation-adjusted damage caps on the weighted average single premiums. Data Collection/Extraction Methods State tort reform laws were identified using Westlaw, LEXIS, and statutory compilations. Legislative repeal and amendment of statutes and court decisions resulting in the overturning or repealing state statutes were also identified using LEXIS. Principal Findings Using a variety of empirical specifications, there was no statistically significant evidence that noneconomic damage caps exerted any meaningful influence on the cost of employer-sponsored health insurance. Conclusions The findings suggest that tort reforms have not translated into insurance savings. PMID:18522666
Mackoff, Barbara L; Meadows, Mary T; Nash, Alice
2017-03-01
The aim of the study is to create a mixed-methods evaluation template to examine the educational experiences and outcomes of participants in the Nurse Manager Fellowship (NMF) sponsored by the American Organization of Nurse Executives (AONE) Foundation. The focus was to capture change as reported by the nurse manager (NM) fellows and the senior leaders who sponsored them and to gain access to the participants' lived experiences as leadership learners. The AONE Foundation's NMF conducts a yearlong professional development program with a cohort of 30 fellows who meet 4 times a year in face-to-face sessions and complete a capstone project. Four data collection methods were used. Participants completed 2 quantitative leadership program outcome surveys, as well as 1 qualitative measure to focus on self-perceived change outcomes. Their sponsors completed a qualitative perception of change measure. The participants' reflections, self-reports, and the sponsor observations capture impactful changes in the NM fellows' increases in knowledge and application in the spheres of self, organization, and community. The enhancement of the participants' self-identification as leaders was also demonstrated. The variety of data collection methods suggests both distinct choices in creating future evaluation templates for the fellowship and approaches that might be adapted by other organizations.
Readability of patient information pamphlets in urogynecology.
Reagan, Krista M L; O'Sullivan, David M; Harvey, David P; Lasala, Christine A
2015-01-01
The purpose of this study was to determine the reading level of frequently used patient information pamphlets and documents in the field of urogynecology. Urogynecology pamphlets were identified from a variety of sources. Readability was determined using 4 different accepted formulas: the Flesch-Kincaid Grade Level, the simple measure of gobbledygook Index, the Coleman-Liau Index, and the Gunning Fog index. The scores were calculated using an online calculator (http://www.readability-score.com). Descriptive statistics were used for analysis. The average of the 4 scores was calculated for each pamphlet. Subsequently, Z-scores were used to standardize the averages between the reading scales. Of the 40 documents reviewed, only a single pamphlet met the National Institutes of Health-recommended reading level. This document was developed by the American Urological Association and was specifically designated as a "Low-Literacy Brochure." The remainder of the patient education pamphlets, from both industry-sponsored and academic-sponsored sources, consistently rated above the recommended reading level for maximum comprehension. The majority of patient education pamphlets, from both industry-sponsored and academic-sponsored sources, are above the reading level recommended by the National Institutes of Health for maximum patient comprehension. Future work should be done to improve the educational resources available to patients by simplifying the verbiage in these documents.
Premium growth and its effect on employer-sponsored insurance.
Vistnes, Jessica; Selden, Thomas
2011-03-01
We use variation in premium inflation and general inflation across geographic areas to identify the effects of downward nominal wage rigidity on employers' health insurance decisions. Using employer level data from the 2000 to 2005 Medical Expenditure Panel Survey-Insurance Component, we examine the effect of premium growth on the likelihood that an employer offers insurance, eligibility rates among employees, continuous measures of employee premium contributions for both single and family coverage, and deductibles. We find that small, low-wage employers are less likely to offer health insurance in response to increased premium inflation, and if they do offer coverage they increase employee contributions and deductible levels. In contrast, larger, low-wage employers maintain their offers of coverage, but reduce eligibility for such coverage. They also increase employee contributions for single and family coverage, but not deductibles. Among high-wage employers, all but the largest increase deductibles in response to cost pressures.
2008-11-07
CAPE CANAVERAL, Fla. -- In Building 1555 at Vandenberg Air Force Base in California, assembly is underway for the Taurus XL rocket that will launch NASA's Orbiting Carbon Observatory, or OCO, spacecraft. In the foreground at left is the boattail; behind it is the Stage 0 Castor 120 motor. At right near the wall (from left) are the Stage 1 and Stage 2 motors, the avionics shelf and the Stage 3 motor. The graphite/epoxy boattail structure provides the transition from the smaller diameter of the Stage 2 motor to the larger diameter of the avionics skirt. The avionics skirt, also a graphite/epoxy structure, supports the avionics shelf and carries the primary structural loads from the fairing and payload cone. The aluminum avionics shelf supports the third stage avionics. The OCO is a new Earth-orbiting mission sponsored by NASA's Earth System Science Pathfinder Program. The launch of OCO is targeted for January. Photo credit: NASA/Randy Beaudoin, VAFB
Stress and morale of academic biomedical scientists.
Holleman, Warren L; Cofta-Woerpel, Ludmila M; Gritz, Ellen R
2015-05-01
Extensive research has shown high rates of burnout among physicians, including those who work in academic health centers. Little is known, however, about stress, burnout, and morale of academic biomedical scientists. The authors interviewed department chairs at one U.S. institution and were told that morale has plummeted in the past five years. Chairs identified three major sources of stress: fear of not maintaining sufficient funding to keep their positions and sustain a career; frustration over the amount of time spent doing paperwork and administrative duties; and distrust due to an increasingly adversarial relationship with the executive leadership.In this Commentary, the authors explore whether declining morale and concerns about funding, bureaucracy, and faculty-administration conflict are part of a larger national pattern. The authors also suggest ways that the federal government, research sponsors, and academic institutions can address these concerns and thereby reduce stress and burnout, increase productivity, and improve overall morale of academic biomedical scientists.
Marching toward reproductive justice: coalitional (re) framing of the March for Women's Lives.
Luna, Zakiya T
2010-01-01
This article examines how coalition frames develop and what happens to that frame after the formal coalition ends. To that end, I analyze the frame shift around the 2004 March for Women's Lives (March). The March initially focused on established ideas of reproductive rights around which the four national mainstream co-sponsors previously organized. However, after a newer reproductive justice organization joined the coalition, material and organizing reflected a shift in framing to reproductive justice. How did this change happen? What are the impacts of this event for the women's movement? Through document analysis and interviews, I trace the negotiations that facilitated this framing shift. I argue that this new coalition frame translated into positive lasting changes in organizing for women's reproductive health even as the coalition dissolved and some of the tensions within the larger women's movement remain.
Grethe, Jeffrey S; Ross, Edward; Little, David; Sanders, Brian; Gupta, Amarnath; Astakhov, Vadim
2009-01-01
This paper presents current progress in the development of semantic data integration environment which is a part of the Biomedical Informatics Research Network (BIRN; http://www.nbirn.net) project. BIRN is sponsored by the National Center for Research Resources (NCRR), a component of the National Institutes of Health (NIH). A goal is the development of a cyberinfrastructure for biomedical research that supports advance data acquisition, data storage, data management, data integration, data mining, data visualization, and other computing and information processing services over the Internet. Each participating institution maintains storage of their experimental or computationally derived data. Mediator-based data integration system performs semantic integration over the databases to enable researchers to perform analyses based on larger and broader datasets than would be available from any single institution's data. This paper describes recent revision of the system architecture, implementation, and capabilities of the semantically based data integration environment for BIRN.
Acquisition Risks in a World of Joint Capabilities: A Study of Interdependency Complexity
2012-12-19
Blvd,Charlotte,NC,28223 8 . PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S...RESPONSIBLE PERSON a. REPORT unclassified b. ABSTRACT unclassified c. THIS PAGE unclassified Standard Form 298 (Rev. 8 -98) Prescribed by ANSI Std...BUSINESS & PUBLIC POLICY NAVAL POSTGRADUATE SCHOOL = = ^Åèìáëáíáçå=oÉëÉ~êÅÜ=mêçÖê~ã= do^ar^qb=p`elli=lc=_rpfkbpp=C=mr_if`=mlif`v= = - 8 - k^s^i
Psaty, Bruce M; Kronmal, Richard A
2008-04-16
Sponsors have a marketing interest to represent their products in the best light. This approach conflicts with scientific standards that require the symmetric and comparable reporting of safety and efficacy data. Selective reporting of the results of clinical trials can misrepresent the risk-benefit profile of drugs. We summarize how the sponsor represented mortality findings associated with rofecoxib in clinical trials of patients with Alzheimer disease or cognitive impairment. We reviewed documents that became available during litigation related to rofecoxib involving Merck & Co, including internal company analyses and information provided by the sponsor to the FDA. We also evaluated information in 2 published articles that reported results of these trials. In one article (reporting results of protocol 091) published in 2004, 11 "non-drug related deaths" were reported (9 deaths among 346 rofecoxib patients and 2 deaths among 346 placebo patients). In another article (reporting results of protocol 078) published in 2005, 39 deaths were reported among patients taking study treatment or within 14 days of the last dose (24 among 725 rofecoxib patients and 15 among 732 placebo patients) and an additional 22 deaths in the off-drug period (17 in rofecoxib patients and 5 in placebo patients). However, these articles did not include analyses or statistical tests of the mortality data, and the 2 articles concluded that regarding safety, rofecoxib is "well tolerated." In contrast, in April 2001, the company's internal intention-to-treat analyses of pooled data from these 2 trials identified a significant increase in total mortality (hazard ratio [HR], 4.43; 95% CI, 1.26-15.53 for protocol 091, and HR, 2.55; 95% CI, 1.17-5.56 for protocol 078), with overall mortality of 34 deaths among 1069 rofecoxib patients and 12 deaths among 1078 placebo patients (HR, 2.99; 95% CI, 1.55-5.77). These mortality analyses were neither provided to the FDA nor made public in a timely fashion. The data submitted by the sponsor to the FDA in a Safety Update Report in July 2001 used on-treatment analysis methods and reported 29 deaths (2.7%) among 1067 rofecoxib patients and 17 deaths (1.6%) among 1075 placebo patients. This on-treatment approach to reporting minimized the appearance of any mortality risk. In December 2001, when the FDA raised safety questions about the submitted safety data, the sponsor did not bring these issues to an institutional review board for review and revealed that there was no data and safety monitoring board for the protocol 078 study. The findings from this case study suggest that additional protections for human research participants, including new approaches for the conduct, oversight, and reporting of industry-sponsored trials, are necessary.
Breakthrough Air Force Capabilities Spawned By Basic Research
2007-04-01
AboutAFOSR/about_history.htm>. 15 Ibid. 16 Ibid. 4 1990s • Titanium Aluminides . AFOSR-sponsored research looked at titanium aluminides , which are...the 1970s, AFOSR sponsored research on ways to increase the strength and fatigue resistance of titanium , aluminum, and nickel alloys used for...High-Efficiency Swept Shock Compressor Blades . AFOSR-sponsored research looked at making rotor blades in axial flow compressors more efficient
Fast Surface Reconstruction and Segmentation with Terrestrial LiDAR Range Data
2009-05-18
UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) University of California at Berkeley,Department of Electrical Engineering and Computer...Sciences,Berkeley,CA,94720 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S...ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION /AVAILABILITY STATEMENT Approved for public release; distribution unlimited 13
The Interaction of High-Speed Turbulence with Flames: Turbulent Flame Speed
2010-08-05
AND ADDRESS(ES) 10. SPONSOR / MONITOR’S ACRONYM(S) 9 . SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 11. SPONSOR / MONITOR’S REPORT NUMBER(S...UL 38 A.Y. Poludnenko (202) 767-6582 05 -08-2010 Memorandum Report Turbulent premixed combustion Turbulence Flamelet Turbulent flame speed Office of...3.4. Stretch factor and the balance between ST and AT ...................................................................... 9 4. Flame surface
Code of Federal Regulations, 2011 CFR
2011-07-01
... 41 Public Contracts and Property Management 4 2011-07-01 2011-07-01 false Are there any special requirements for sponsoring or funding a conference at a hotel, motel or other place of public accommodation... Responsibilities § 301-74.14 Are there any special requirements for sponsoring or funding a conference at a hotel...
2013-01-01
9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11 . SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION...computer programs, this cadet team is developing this new type of model for a radio controlled aircraft, which will be verified through experimental...complement of researchers available to mentor and lead cadets in their development as engineers and officers,” said McLaughlin . 11 Research at USAFA
Code of Federal Regulations, 2014 CFR
2014-01-01
... evaluation, the NSPM will make every attempt to notify the sponsor at least one (1) week, but in no case less... may change from one 12-month period to the next 12-month period as long as the sponsor sponsors and uses at least one FFS at least once during the prescribed period. No minimum number of hours or minimum...
Code of Federal Regulations, 2012 CFR
2012-01-01
... evaluation, the NSPM will make every attempt to notify the sponsor at least one (1) week, but in no case less... may change from one 12-month period to the next 12-month period as long as the sponsor sponsors and uses at least one FFS at least once during the prescribed period. No minimum number of hours or minimum...
Code of Federal Regulations, 2013 CFR
2013-01-01
... evaluation, the NSPM will make every attempt to notify the sponsor at least one (1) week, but in no case less... may change from one 12-month period to the next 12-month period as long as the sponsor sponsors and uses at least one FFS at least once during the prescribed period. No minimum number of hours or minimum...
The Evolving Private Military Sector: A Survey
2008-04-23
PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Postgraduate School,Graduate School of Business and Public Policy,Monterey,CA,93943 8...PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT...sector have a website which offers information about the organization . Using these and other resources, we assembled more detailed data on
Code of Federal Regulations, 2010 CFR
2010-07-01
... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false Are there any special requirements for sponsoring or funding a conference at a hotel, motel or other place of public accommodation... Responsibilities § 301-74.14 Are there any special requirements for sponsoring or funding a conference at a hotel...
Health Monitor Instrument 6 Months Post Deployment
2004-06-01
Netherlands, Health Care Policy. PO box 20701, 2500 ES The Hague THE NETHERLANDS 8. PERFORMING ORGANIZATION REPORT NUMBER 9 . SPONSORING/MONITORING...AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11 . SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION/AVAILABILITY STATEMENT Approved...questionnaires with personal interviews. Occup Environ Med 1997;54:54- 9 . Bouter LM, Dongen MCJM van. Epidemiologisch onderzoek: opzet en interpretatie
Klein, E; Solomon, A J; Corboy, J; Bernat, J
2016-07-01
Perceived physician financial conflicts of interest of can affect patient trust. Payment to physicians for industry sponsored clinical trials in multiple sclerosis is a relatively new potential source of physician conflict of interest. There is limited available data on how physician payment for trial involvement in multiple sclerosis clinical trials may influence patient trust. To understand how patient trust is influenced by information about physician payment for multiple sclerosis clinical trials. An anonymous online instrument was developed. 597 people with multiple sclerosis participated in the study. The study found that 61% of patients who had not previously participated in a clinical trial estimated that they would have lower levels of trust in their physician if the physician was paid for involvement in their clinical trial. Among former clinical trial participants, 38% self-reported a lower level of trust. Other potential physician-industry relationships, such as industry consulting or giving industry-sponsored talks, also adversely affected trust, though to a lesser extent than physician payment for subject participation in clinical trials. Results of this study demonstrate that physician payment for study participation in multiple sclerosis clinical trials is a potential conflict that can adversely affect patient trust. Copyright © 2016 Elsevier B.V. All rights reserved.
Perez, Raymond; Archdeacon, Patrick; Roach, Nancy; Goodwin, Robert; Jarow, Jonathan; Stuccio, Nina; Forrest, Annemarie
2017-01-01
Background/aims: The Food and Drug Administration’s final rule on investigational new drug application safety reporting, effective from 28 March 2011, clarified the reporting requirements for serious and unexpected suspected adverse reactions occurring in clinical trials. The Clinical Trials Transformation Initiative released recommendations in 2013 to assist implementation of the final rule; however, anecdotal reports and data from a Food and Drug Administration audit indicated that a majority of reports being submitted were still uninformative and did not result in actionable changes. Clinical Trials Transformation Initiative investigated remaining barriers and potential solutions to full implementation of the final rule by polling and interviewing investigators, clinical research staff, and sponsors. Methods: In an opinion-gathering effort, two discrete online surveys designed to assess challenges and motivations related to management of expedited (7- to 15-day) investigational new drug safety reporting processes in oncology trials were developed and distributed to two populations: investigators/clinical research staff and sponsors. Data were collected for approximately 1 year. Twenty-hour-long interviews were also conducted with Clinical Trials Transformation Initiative–nominated interview participants who were considered as having extensive knowledge of and experience with the topic. Interviewees included 13 principal investigators/study managers/research team members and 7 directors/vice presidents of pharmacovigilance operations from 5 large global pharmaceutical companies. Results: The investigative site’s responses indicate that too many individual reports are still being submitted, which are time-consuming to process and provide little value for patient safety assessments or for informing actionable changes. Fewer but higher quality reports would be more useful, and the investigator and staff would benefit from sponsors’“filtering” of reports and increased sponsor communication. Sponsors replied that their greatest challenges include (1) lack of global harmonization in reporting rules, (2) determining causality, and (3) fear of regulatory repercussions. Interaction with the Food and Drug Administration has helped improve sponsors’ adherence to the final rule, and sponsors would benefit from increased communication with the Food and Drug Administration and educational materials. Conclusion: The goal of the final rule is to minimize uninformative safety reports so that important safety signals can be captured and communicated early enough in a clinical program to make changes that help ensure patient safety. Investigative staff and sponsors acknowledge that the rule has not been fully implemented although they agree with the intention. Clinical Trials Transformation Initiative will use the results from the surveys and interviews to develop new recommendations and educational materials that will be available to sponsors to increase compliance with the final rule and facilitate discussion between sponsors, investigators, and Food and Drug Administration representatives. PMID:28345368
DOE Office of Scientific and Technical Information (OSTI.GOV)
Li, Yan; Wei, Zhehao; Gao, Feng
2015-05-01
In this work, CeO2 nanocubes with controlled particle size and dominating (100) facets are synthesized as supports for VOx catalysts. Combined TEM, SEM, XRD, and Raman study reveals that the oxygen vacancy density of CeO2 supports can be tuned by tailoring the particle sizes without altering the dominating facets, where smaller particle sizes result in larger oxygen vacancy densities. At the same vanadium coverage, the VOx catalysts supported on small-sized CeO2 supports with higher oxygen defect densities exhibit promoted redox property and lower activation energy for methoxyl group decomposition, as evidenced by H2-TPR and methanol TPD study. These results furthermore » confirm that the presence of oxygen vacancies plays an important role in promoting the activity of VOx species in methanol oxidation. We gratefully acknowledge financial support from the U.S. Department of Energy (DOE), Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences, and Biosciences. Part of this work was conducted in the William R. Wiley Environmental Molecular Sciences Laboratory (EMSL), a national scientific user facility sponsored by DOE’s Office of Biological and Environmental Research and located at Pacific Northwest National Laboratory (PNNL). PNNL is a multiprogram national laboratory operated for the DOE by Battelle.« less
Seccombe, K; Clarke, L L; Coward, R T
1994-01-01
Using a nationally representative sample of employed adults from the 1987 National Medical Expenditure Survey (NMES), this research explores differences in the incidence and predictors of employer-sponsored health insurance among Hispanics, blacks, and whites. The data suggest that: 1) whites are most likely, and Hispanics are least likely, to have employer-sponsored medical insurance in their own name, or in the name of another individual; 2) Hispanics are most likely, and whites are least likely, to be completely uninsured; and 3) the factors which increase the odds of receiving employer-sponsored coverage in one's own name are relatively similar across racial groups, though they differ substantially in magnitude.
Emery, Sherry; Wakefield, Melanie A; Terry-McElrath, Yvonne; Saffer, Henry; Szczypka, Glen; O'Malley, Patrick M; Johnston, Lloyd D; Chaloupka, Frank J; Flay, Brian
2005-07-01
Recent state budget crises have dramatically reduced funding for state-sponsored antitobacco media campaigns. If campaigns are associated with reduced smoking, such cuts could result in long-term increases in state health care costs. Commercial ratings data on mean audience exposure to antitobacco advertising that appeared on network and cable television across the largest 75 media markets in the United States for 1999 through 2000 were combined with nationally representative survey data from school-based samples of youth in the contiguous 48 states. Multivariate regression models were used to analyze associations between mean exposure to state antitobacco advertising and youth smoking-related beliefs and behaviors, controlling for individual and environmental factors usually associated with youth smoking and other televised tobacco-related advertising. Mean exposure to at least 1 state-sponsored antitobacco advertisement in the past 4 months was associated with lower perceived rates of friends' smoking (odds ratio [OR], 0.72; 95% confidence interval [CI], 0.58-0.88), greater perceived harm of smoking (OR, 1.25; 95% CI, 1.11-1.42), stronger intentions not to smoke in the future (OR, 1.43; 95% CI, 1.17-1.74), and lower odds of being a smoker (OR, 0.74; 95% CI, 0.63-0.88). To our knowledge, this study is the first to explore the potential impact of state-sponsored antitobacco media campaigns while controlling for other tobacco-related advertising and other tobacco control policies. State-sponsored antitobacco advertising is associated with desired outcomes of greater antitobacco sentiment and reduced smoking among youth. Recent cuts in these campaigns may have future negative health and budgetary consequences.
Holbein, M E Blair; Berglund, Jelena Petrovic; O'Reilly, Erin K; Hartman, Karen; Speicher, Lisa A; Adamo, Joan E; O'Riordan, Gerri; Brown, Jennifer Swanton; Schuff, Kathryn G
2014-06-01
The objective of this study was to provide recommendations for provision of training for sponsor and investigators at Academic Health Centers. A subgroup of the Investigational New Drug/Investigational Device Exemption (IND/IDE) Task Force of the Clinical and Translational Science Award (CTSA) program Regulatory Knowledge Key Function Committee was assembled to specifically address how clinical investigators who hold an IND/IDE and thus assume the role of sponsor-investigators are adequately trained to meet the additional regulatory requirements of this role. The participants who developed the recommendations were representatives of institutions with IND/IDE support programs. Through an informal survey, the task force determined that a variety and mix of models are used to provide support for IND/IDE holders within CTSA institutions. In addition, a CTSA consortium-wide resources survey was used. The participants worked from the models and survey results to develop consensus recommendations to address institutional support, training content, and implementation. The CTSA IND/IDE Task Force recommendations are as follows: (1) Institutions should assess the scope of Food and Drug Administration-regulated research, perform a needs analysis, and provide resources to implement a suitable training program; (2) The model of training program should be tailored to each institution; (3) The training should specifically address the unique role of sponsor-investigators, and the effectiveness of training should be evaluated regularly by methods that fit the model adopted by the institution; and (4) Institutional leadership should mandate sponsor-investigator training and effectively communicate the necessity and availability of training.
Chin, Lisa Judy; Rifai-Bashjawish, Hoda; Kleinert, Kelly; Saltman, Alexandra; Leu, Cheng-Shiun; Klitzman, Robert
2011-09-01
We explored how often journal articles reporting HIV research sponsored by a developed country, but conducted in a developing country, mention research ethics committee (REC) approval from both countries, and what factors are involved. Of all such 2007 articles on Medline conducted in one of four developing countries (N = 154), only 52% mentioned such dual approval. Mention of dual vs. single approval was more likely among articles with ≥ 50% sponsor country authors, and the United States as the sponsor country. Also, dual approval was more likely among articles that mentioned informed consent and funding, had ≥ 50% sponsor country authors, were biomedical (vs. psychosocial), and appeared in journals adopting International Committee Medical Journal Editors (ICMJE) guidelines. Dual approval was thus obtained in only half of the articles and was associated with ethical and logistic issues, indicating the need for clearer and more universally accepted guidelines.
Nonstationary Root Causes of Cobb’s Paradox
2010-07-01
AUTHOR( S ) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) Defense Acquisition University...9820 Belvoir Road, Suite 3,Fort Belvoir,VA,22060-5565 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME( S ) AND ADDRESS...ES) 10. SPONSOR/MONITOR’S ACRONYM( S ) 11. SPONSOR/MONITOR’S REPORT NUMBER( S ) 12. DISTRIBUTION/AVAILABILITY STATEMENT Approved for public release
Multi-Objective Optimization of System Capability Satisficing in Defense Acquisition
2012-04-30
sponsored by the USD(AT&L). Second, we issue an annual internal call for proposals to seek NPS faculty research supporting the interests of our...program sponsors. Finally, we serve as a “broker” to market specific research topics identified by our sponsors to NPS graduate students. This three...expanding the technology readiness level within defense acquisition. International Journal of Defense Acquisition Management, 1, 39–58. Tan, W
2012-07-23
CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING...ORGANIZATION NAME( S ) AND ADDRESS(ES) Marine Corps Warfighting Laboratory,Wargaming Division,3255 Meyers Avenue (Newlin Hall),Quantico,VA,22134 8...PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME( S ) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM( S ) 11. SPONSOR/MONITOR’S
Combination of Evidence for Effective Web Search
2010-11-01
SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION /AVAILABILITY...STATEMENT Approved for public release; distribution unlimited 13. SUPPLEMENTARY NOTES Presented at the Nineteenth Text REtrieval Conference (TREC...use that page to expand. This happens often with named entity queries (such as ‘the secret garden’ or ‘ starbucks ’). However, when the query is
Immunotherapeutic Cell-Based Vaccine to Combat Metastatic Breast Cancer
1999-07-01
approved by the UMBC IACUC and are consistent with the NIH guidelines for the humane treatment of laboratory animals. Antibodies: Protein A or Protein... IACUC guidelines. Surgery. All surgical supplies and surgical equipment were purchased from Henry Schein Veterinary & Medical Supply Catalog... AAI Name of Sponsor: Ostrand-Rosenberg, Suzanne Phone/Fax Number of Sponsor; 410-455-2237, 410-455-3875 E-mail of the Sponsor: srosenbe@umbc.edu