Wind Tunnel Visualization of the Flow Over a Full-Scale F/A-18 Aircraft

NASA Technical Reports Server (NTRS)

Lanser, Wendy R.; Botha, Gavin J.; James, Kevin D.; Crowder, James P.; Schmitz, Fredric H. (Technical Monitor)

1994-01-01

The proposed paper presents flow visualization performed during experiments conducted on a full-scale F/A-18 aircraft in the 80- by 120-Foot Wind-Tunnel at NASA Ames Research Center. This investigation used both surface and off-surface flow visualization techniques to examine the flow field on the forebody, canopy, leading edge extensions (LEXs), and wings. The various techniques used to visualize the flow field were fluorescent tufts, flow cones treated with reflective material, smoke in combination with a laser light sheet, and a video imaging system. The flow visualization experiments were conducted over an angle of attack range from 20deg to 45deg and over a sideslip range from -10deg to 10deg. The results show regions of attached and separated flow on the forebody, canopy, and wings. Additionally, the vortical flow is clearly visible over the leading-edge extensions, canopy, and wings.

Stereoscopic Imaging in Hypersonics Boundary Layers using Planar Laser-Induced Fluorescence

NASA Technical Reports Server (NTRS)

Danehy, Paul M.; Bathel, Brett; Inman, Jennifer A.; Alderfer, David W.; Jones, Stephen B.

2008-01-01

Stereoscopic time-resolved visualization of three-dimensional structures in a hypersonic flow has been performed for the first time. Nitric Oxide (NO) was seeded into hypersonic boundary layer flows that were designed to transition from laminar to turbulent. A thick laser sheet illuminated and excited the NO, causing spatially-varying fluorescence. Two cameras in a stereoscopic configuration were used to image the fluorescence. The images were processed in a computer visualization environment to provide stereoscopic image pairs. Two methods were used to display these image pairs: a cross-eyed viewing method which can be viewed by naked eyes, and red/blue anaglyphs, which require viewing through red/blue glasses. The images visualized three-dimensional information that would be lost if conventional planar laser-induced fluorescence imaging had been used. Two model configurations were studied in NASA Langley Research Center's 31-Inch Mach 10 Air Wind tunnel. One model was a 10 degree half-angle wedge containing a small protuberance to force the flow to transition. The other model was a 1/3-scale, truncated Hyper-X forebody model with blowing through a series of holes to force the boundary layer flow to transition to turbulence. In the former case, low flowrates of pure NO seeded and marked the boundary layer fluid. In the latter, a trace concentration of NO was seeded into the injected N2 gas. The three-dimensional visualizations have an effective time resolution of about 500 ns, which is fast enough to freeze this hypersonic flow. The 512x512 resolution of the resulting images is much higher than high-speed laser-sheet scanning systems with similar time response, which typically measure 10-20 planes.

Visualization of irrigant flow and cavitation induced by Er:YAG laser within a root canal model.

PubMed

Matsumoto, Himeka; Yoshimine, Yoshito; Akamine, Akifumi

2011-06-01

Laser-activated irrigation (LAI) has recently been introduced as an innovative method for root canal irrigation. However, there is limited information about the cleaning mechanism of an Er:YAG laser. In this study, we visualized the action of laser-induced bubbles and fluid flow in vitro to better understand the physical mechanisms underlying LAI. An Er:YAG laser was equipped with a novel cone-shaped tip with a lateral emission rate of approximately 80%. Laser light was emitted at a pulse energy of 30, 50, or 70 mJ (output energy: 11, 18, or 26 mJ) and a repetition rate of 1 or 20 pulses per second, without air or water spray. Fluid flow dynamics in a root canal model were observed by using glass-bead tracers under a high-speed camera. Moreover, laser-induced bubble patterns were visualized in both free water and the root canal model. Tracers revealed high-speed motion of the fluid. A full cycle of expansion and implosion of vapor and secondary cavitation bubbles were clearly observed. In free water, the vapor bubble expanded for 220 microseconds, and its shape resembled that of an apple. In the root canal model, the vapor bubble expanded in a vertical direction along the canal wall, and bubble expansion continued for ≥700 microseconds. Furthermore, cavitation bubbles were created much more frequently in the canal model than in free water. These results suggest that the cleaning mechanism of an Er:YAG laser within the root canal might depend on rapid fluid motion caused by expansion and implosion of laser-induced bubbles. Copyright © 2011 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

Planar laser-induced fluorescence (PLIF) investigation of hypersonic flowfields in a Mach 10 wind tunnel

NASA Technical Reports Server (NTRS)

Danehy, Paul M.; Wilkes, Jennifer A.; Aderfer, David W.; Jones, Stephen B.; Robbins, Anthony W.; Pantry, Danny P.; Schwartz, Richard J.

2006-01-01

Planar laser-induced fluorescence (PLIF) of nitric oxide (NO) was used to visualize four different hypersonic flowfields in the NASA Langley Research Center 31-Inch Mach 10 Air wind tunnel. The four configurations were: (1) the wake flowfield of a fuselage-only X-33 lifting body, (2) flow over a flat plate containing a rectangular cavity, (3) flow over a 70deg blunted cone with a cylindrical afterbody, formerly studied by an AGARD working group, and (4) an Apollo-geometry entry capsule - relevant to the Crew Exploration Vehicle currently being developed by NASA. In all cases, NO was seeded into the flowfield through tubes inside or attached to the model sting and strut. PLIF was used to visualize the NO in the flowfield. In some cases pure NO was seeded into the flow while in other cases a 5% NO, 95% N2 mix was injected. Several parameters were varied including seeding method and location, seeding mass flow rate, model angle of attack and tunnel stagnation pressure, which varies the unit Reynolds number. The location of the laser sheet was as also varied to provide three dimensional flow information. Virtual Diagnostics Interface (ViDI) technology developed at NASA Langley was used to visualize the data sets in post processing. The measurements demonstrate some of the capabilities of the PLIF method for studying hypersonic flows.

Instantaneous three-dimensional visualization of concentration distributions in turbulent flows with crossed-plane laser-induced fluorescence imaging

NASA Astrophysics Data System (ADS)

Hoffmann, A.; Zimmermann, F.; Scharr, H.; Krömker, S.; Schulz, C.

2005-01-01

A laser-based technique for measuring instantaneous three-dimensional species concentration distributions in turbulent flows is presented. The laser beam from a single laser is formed into two crossed light sheets that illuminate the area of interest. The laser-induced fluorescence (LIF) signal emitted from excited species within both planes is detected with a single camera via a mirror arrangement. Image processing enables the reconstruction of the three-dimensional data set in close proximity to the cutting line of the two light sheets. Three-dimensional intensity gradients are computed and compared to the two-dimensional projections obtained from the two directly observed planes. Volume visualization by digital image processing gives unique insight into the three-dimensional structures within the turbulent processes. We apply this technique to measurements of toluene-LIF in a turbulent, non-reactive mixing process of toluene and air and to hydroxyl (OH) LIF in a turbulent methane-air flame upon excitation at 248 nm with a tunable KrF excimer laser.

High speed digital holographic interferometry for hypersonic flow visualization

NASA Astrophysics Data System (ADS)

Hegde, G. M.; Jagdeesh, G.; Reddy, K. P. J.

2013-06-01

Optical imaging techniques have played a major role in understanding the flow dynamics of varieties of fluid flows, particularly in the study of hypersonic flows. Schlieren and shadowgraph techniques have been the flow diagnostic tools for the investigation of compressible flows since more than a century. However these techniques provide only the qualitative information about the flow field. Other optical techniques such as holographic interferometry and laser induced fluorescence (LIF) have been used extensively for extracting quantitative information about the high speed flows. In this paper we present the application of digital holographic interferometry (DHI) technique integrated with short duration hypersonic shock tunnel facility having 1 ms test time, for quantitative flow visualization. Dynamics of the flow fields in hypersonic/supersonic speeds around different test models is visualized with DHI using a high-speed digital camera (0.2 million fps). These visualization results are compared with schlieren visualization and CFD simulation results. Fringe analysis is carried out to estimate the density of the flow field.

NASA Dryden flow visualization facility

NASA Technical Reports Server (NTRS)

Delfrate, John H.

1995-01-01

This report describes the Flow Visualization Facility at NASA Dryden Flight Research Center, Edwards, California. This water tunnel facility is used primarily for visualizing and analyzing vortical flows on aircraft models and other shapes at high-incidence angles. The tunnel is used extensively as a low-cost, diagnostic tool to help engineers understand complex flows over aircraft and other full-scale vehicles. The facility consists primarily of a closed-circuit water tunnel with a 16- x 24-in. vertical test section. Velocity of the flow through the test section can be varied from 0 to 10 in/sec; however, 3 in/sec provides optimum velocity for the majority of flow visualization applications. This velocity corresponds to a unit Reynolds number of 23,000/ft and a turbulence level over the majority of the test section below 0.5 percent. Flow visualization techniques described here include the dye tracer, laser light sheet, and shadowgraph. Limited correlation to full-scale flight data is shown.

UV reactor flow visualization and mixing quantification using three-dimensional laser-induced fluorescence.

PubMed

Gandhi, Varun; Roberts, Philip J W; Stoesser, Thorsten; Wright, Harold; Kim, Jae-Hong

2011-07-01

Three-dimensional laser-induced fluorescence (3DLIF) was applied to visualize and quantitatively analyze mixing in a lab-scale UV reactor consisting of one lamp sleeve placed perpendicular to flow. The recirculation zone and the von Karman vortex shedding that commonly occur in flows around bluff bodies were successfully visualized. Multiple flow paths were analyzed by injecting the dye at various heights with respect to the lamp sleeve. A major difference in these pathways was the amount of dye that traveled close to the sleeve, i.e., a zone of higher residence time and higher UV exposure. Paths away from the center height had higher velocities and hence minimal influence by the presence of sleeve. Approach length was also characterized in order to increase the probability of microbes entering the region around the UV lamp. The 3DLIF technique developed in this study is expected to provide new insight on UV dose delivery useful for the design and optimization of UV reactors. Copyright © 2011 Elsevier Ltd. All rights reserved.

Stereoscopic Planar Laser-Induced Fluorescence Imaging at 500 kHz

NASA Technical Reports Server (NTRS)

Medford, Taylor L.; Danehy, Paul M.; Jones, Stephen B.; Jiang, N.; Webster, M.; Lempert, Walter; Miller, J.; Meyer, T.

2011-01-01

A new measurement technique for obtaining time- and spatially-resolved image sequences in hypersonic flows is developed. Nitric-oxide planar laser-induced fluorescence (NO PLIF) has previously been used to investigate transition from laminar to turbulent flow in hypersonic boundary layers using both planar and volumetric imaging capabilities. Low flow rates of NO were typically seeded into the flow, minimally perturbing the flow. The volumetric imaging was performed at a measurement rate of 10 Hz using a thick planar laser sheet that excited NO fluorescence. The fluorescence was captured by a pair of cameras having slightly different views of the flow. Subsequent stereoscopic reconstruction of these images allowed the three-dimensional flow structures to be viewed. In the current paper, this approach has been extended to 50,000 times higher repetition rates. A laser operating at 500 kHz excites the seeded NO molecules, and a camera, synchronized with the laser and fitted with a beam-splitting assembly, acquires two separate images of the flow. The resulting stereoscopic images provide three-dimensional flow visualizations at 500 kHz for the first time. The 200 ns exposure time in each frame is fast enough to freeze the flow while the 500 kHz repetition rate is fast enough to time-resolve changes in the flow being studied. This method is applied to visualize the evolving hypersonic flow structures that propagate downstream of a discrete protuberance attached to a flat plate. The technique was demonstrated in the NASA Langley Research Center s 31-Inch Mach 10 Air Tunnel facility. Different tunnel Reynolds number conditions, NO flow rates and two different cylindrical protuberance heights were investigated. The location of the onset of flow unsteadiness, an indicator of transition, was observed to move downstream during the tunnel runs, coinciding with an increase in the model temperature.

Beam-modulation methods in quantitative and flow visualization holographic interferometry

NASA Technical Reports Server (NTRS)

Decker, A.

1986-01-01

This report discusses heterodyne holographic interferometry and time-average holography with a frequency shifted reference beam. Both methods will be used for the measurement and visualization of internal transonic flows, where the target facility is a flutter cascade. The background and experimental requirements for both methods are reviewed. Measurements using heterodyne holographic interferometry are presented. The performance of the laser required for time-average holography of time-varying transonic flows is discussed.

Beam-modulation methods in quantitative and flow-visualization holographic interferometry

NASA Technical Reports Server (NTRS)

Decker, Arthur J.

1986-01-01

Heterodyne holographic interferometry and time-average holography with a frequency shifted reference beam are discussed. Both methods will be used for the measurement and visualization of internal transonic flows where the target facility is a flutter cascade. The background and experimental requirements for both methods are reviewed. Measurements using heterodyne holographic interferometry are presented. The performance of the laser required for time-average holography of time-varying transonic flows is discussed.

Ocular haemodynamic changes after single treatment with photodynamic therapy assessed with non-invasive techniques.

PubMed

Maar, Noemi; Pemp, Berthold; Kircher, Karl; Luksch, Alexandra; Weigert, Günther; Polska, Elzbieta; Tittl, Michael; Stur, Michael; Schmetterer, Leopold

2009-09-01

To investigate in patients with neovascular age-related macular degeneration (ARMD) the changes in ocular perfusion caused by single treatment with photodynamic therapy (PDT) by different non-invasive methods; to evaluate correlations between relative changes of ocular haemodynamic parameters after PDT among each other and compared to morphological parameters; and to assess this in relation to early changes of visual acuity. 17 consecutive patients with subfoveal choroidal neovascularization (CNV) caused by ARMD scheduled for PDT without previous PDT treatment (four patients with predominantly classic CNV and 13 patients with occult CNV). best-corrected visual acuity (before PDT, 6 and 8 weeks after PDT), fundus photography, fluorescein angiography, haemodynamic measurements with laser Doppler flowmetry (LDF), laser interferometry and ocular blood flow (OBF) tonometry (baseline and 1, 2, 6 and 8 weeks after treatment). choroidal blood flow (CHBF), fundus pulsation amplitude (FPA), pulsatile ocular blood flow (POBF), visual acuity. Changes smaller than 20% were considered clinically irrelevant. Ocular haemodynamic parameters did not change significantly in the follow-up period. Changes of haemodynamic parameters showed no correlation to treatment spot, morphological changes or visual acuity. Changes of visual acuity were comparable to results of earlier studies. Single treatment with PDT did not modify ocular blood flow parameters above 20% as assessed with different non-invasive methods.

Flow Visualization Techniques in Wind Tunnel Tests of a Full-Scale F/A-18 Aircraft

NASA Technical Reports Server (NTRS)

Lanser, Wendy R.; Botha, Gavin J.; James, Kevin D.; Bennett, Mark; Crowder, James P.; Cooper, Don; Olson, Lawrence (Technical Monitor)

1994-01-01

The proposed paper presents flow visualization performed during experiments conducted on a full-scale F/A-18 aircraft in the 80- by 120-Foot Wind-Tunnel at NASA Ames Research Center. The purpose of the flow-visualization experiments was to document the forebody and leading edge extension (LEX) vortex interaction along with the wing flow patterns at high angles of attack and low speed high Reynolds number conditions. This investigation used surface pressures in addition to both surface and off-surface flow visualization techniques to examine the flow field on the forebody, canopy, LEXS, and wings. The various techniques used to visualize the flow field were fluorescent tufts, flow cones treated with reflective material, smoke in combination with a laser light sheet, and a video imaging system for three-dimension vortex tracking. The flow visualization experiments were conducted over an angle of attack range from 20 deg to 45 deg and over a sideslip range from -10 deg to 10 deg. The various visualization techniques as well as the pressure distributions were used to understand the flow field structure. The results show regions of attached and separated flow on the forebody, canopy, and wings as well as the vortical flow over the leading-edge extensions. This paper will also present flow visualization comparisons with the F-18 HARV flight vehicle and small-scale oil flows on the F-18.

Characterization of the NASA Langley Arc Heated Scramjet Test Facility Using NO PLIF

NASA Technical Reports Server (NTRS)

Kidd, F. Gray, III; Narayanaswamy, Venkateswaran; Danehy, Paul M.; Inman, Jennifer A.; Bathel, Brett F.; Cabell, Karen F.; Hass, Neal E.; Capriotti, Diego P.; Drozda, Tomasz G.; Johansen, Criag T.

2014-01-01

The nitric oxide planar laser-induced fluorescence (NO PLIF) imaging was used to characterize the air flow of the NASA Langley Arc Heated Scramjet Test Facility (AHSTF) configured with a Mach 6 nozzle. The arc raises the enthalpy of the test gas in AHSTF, producing nitric oxide. Nitric oxide persists as the temperature drops through the nozzle into the test section. NO PLIF was used to qualitatively visualize the flowfield at different experimental conditions, measure the temperature of the gas flow exiting the facility nozzle, and visualize the wave structure downstream of the nozzle at different operating conditions. Uniformity and repeatability of the nozzle flow were assessed. Expansion and compression waves on the free-jet shear layer as the nozzle flow expands into the test section were visualized. The main purpose of these experiments was to assess the uniformity of the NO in the freestream gas for planned experiments, in which NO PLIF will be used for qualitative fuel-mole-fraction sensitive imaging. The shot-to-shot fluctuations in the PLIF signal, caused by variations in the overall laser intensity as well as NO concentration and temperature variations in the flow was 20-25% of the mean signal, as determined by taking the standard deviation of a set of images obtained at constant conditions and dividing by the mean. The fluctuations within individual images, caused by laser sheet spatial variations as well as NO concentration and temperature variations in the flow, were about 28% of the mean in images, determined by taking standard deviation within individual images, dividing by the mean in the same image and averaged over the set of images. Applying an averaged laser sheet intensity correction reduced the within-image intensity fluctuations to about 10% suggesting that the NO concentration is uniform to within 10%. There was no significant difference in flow uniformity between the low and high enthalpy settings. While not strictly quantitative, the temperature maps show qualitative agreement with the computations of the flow.

Holographic cinematography of time-varying reflecting and time-varying phase objects using a Nd:YAG laser.

PubMed

Decker, A J

1982-03-01

The use of a Nd:YAG laser to record holographic motion pictures of time-varying reflecting objects and time-varying phase objects is discussed. Sample frames from both types of holographic motion pictures are presented. The holographic system discussed is intended for three-dimensional flow visualization of the time-varying flows that occur in jet-engine components.

Holographic cinematography of time-varying reflecting and time-varying phase objects using a Nd:YAG laser

NASA Technical Reports Server (NTRS)

Decker, A. J.

1982-01-01

The use of a Nd:YAG laser to record holographic motion pictures of time-varying reflecting objects and time-varying phase objects is discussed. Sample frames from both types of holographic motion pictures are presented. The holographic system discussed is intended for three-dimensional flow visualization of the time-varying flows that occur in jet-engine components.

Exploratory flow visualization investigation of mast-mounted sights in presence of a rotor

NASA Technical Reports Server (NTRS)

Ghee, Terence A.; Kelley, Henry L.

1995-01-01

A flow visualization investigation with a laser light sheet system was conducted on a 27-percent-scale AH-64 attack helicopter model fitted with two mast-mounted sights in the langley 14- by 22-foot subsonic tunnel. The investigation was conducted to identify aerodynamic phenomena that may have contributed to adverse vibration encountered during full-scale flight of the AH-64D apache/longbow helicopter with an asymmetric mast-mounted sight. Symmetric and asymmetric mast-mounted sights oriented at several skew angles were tested at simulated forward and rearward flight speeds of 30 and 45 knots. A laser light sheet system was used to visualize the flow in planes parallel to and perpendicular to the free-stream flow. Analysis of these flow visualization data identified frequencies of flow patterns in the wake shed from the sight, the streamline angle at the sight, and the location where the shed wake crossed the rotor plane. Differences in wake structure were observed between the sight configurations and various skew angles. Analysis of lateral light sheet plane data implied significant vortex structure in the wake of the asymmetric mast-mounted sight in the configuration that produced maximum in-flight vibration. The data showed no significant vortex structure in the wake of the asymmetric and symmetric configurations that produced no increase in in-flight adverse vibration.

Visualization of the Flow at the Tip of a High Speed Axial Flow Turbine Rotor Blade - An Assessment of Flow Visualisation Techniques and the Requirement of the Experimental Turbine.

DTIC Science & Technology

1987-11-01

71 AD-AI89 929 UI4A ~l HOFTEFOJA N TIPO IO PE /L S LO TUIN~. TCHN ?IRAEL’ITF 4XHH F IDNE AL. T U 87 AFOs -8-U N uNCLASSIFIED NIF-: Hrp li1.0 a18...Pulse tracer injection 16. 9) Detector sensor 17- 10) Focussed photomultiplier 17 Conceptual philosophy for the experimental turbine 18 Preliminary...tracing 35 2) Pulsed fluorescence 35 3) Single spot laser sensor 36 4) Two spot laser 36 5) Localised smoke pockets 37 6) Laser pulse smoke generation

Intraoperative Fluorescence Cerebral Angiography by Laser Surgical Microscopy: Comparison With Xenon Microscopy and Simultaneous Observation of Cerebral Blood Flow and Surrounding Structures.

PubMed

Ito, Yuhei; Suzuki, Kyouichi; Ichikawa, Tsuyoshi; Watanabe, Yoichi; Sato, Taku; Sakuma, Jun; Saito, Kiyoshi

2018-06-12

Laser surgical microscopes should enable uniform illumination of the operative field, and require less luminous energy compared with existing xenon surgical microscopes. To examine the utility of laser illumination in fluorescence cerebral angiography. Fluorescein sodium (fluorescein) was used as a fluorescent dye. We first compared the clarity of cerebral blood flow images collected by fluorescence angiography between the laser illumination and xenon illumination methods. We then assessed use of the laser illuminator for simultaneous observation of blood flow and surrounding structures during fluorescence angiography. Furthermore, the study was designed to evaluate usefulness of the thus determined excitation light in clinical cases. Fluorescence angiography using blue light laser for excitation provided higher clarity and contrast blood flow images compared with using blue light generated from a xenon lamp. Further, illumination with excitation light consisting of a combination of 3 types of laser (higher level of blue light, no green light, and lower level of red light) enabled both blood flow and surrounding structures to be observed through the microscope directly by the surgeon. Laser-illuminated fluorescence angiography provides high clarity and contrast images of cerebral blood flow. Further, a laser providing strong blue light and weak red light for excitation light enables simultaneous visual observation of fluorescent blood flow and surrounding structures by the surgeon using a surgical microscope. Overall, these data suggest that laser surgical microscopes are useful for both ordinary operative manipulations and fluorescence angiography.

A vapor generator for transonic flow visualization

NASA Technical Reports Server (NTRS)

Bruce, Robert A.; Hess, Robert W.; Rivera, Jose A., Jr.

1989-01-01

A vapor generator was developed for use in the NASA Langley Transonic Dynamics Tunnel (TDT). Propylene glycol was used as the vapor material. The vapor generator system was evaluated in a laboratory setting and then used in the TDT as part of a laser light sheet flow visualization system. The vapor generator provided satisfactory seeding of the air flow with visible condensate particles, smoke, for tests ranging from low subsonic through transonic speeds for tunnel total pressures from atmospheric pressure down to less than 0.1 atmospheric pressure.

The design and instrumentation of the Purdue annular cascade facility with initial data acquisition and analysis

NASA Technical Reports Server (NTRS)

Stauter, R. C.; Fleeter, S.

1982-01-01

Three dimensional aerodynamic data, required to validate and/or indicate necessary refinements to inviscid and viscous analyses of the flow through turbomachine blade rows, are discussed. Instrumentation and capabilities for pressure measurement, probe insertion and traversing, and flow visualization are reviewed. Advanced measurement techniques including Laser Doppler Anemometers, are considered. Data processing is reviewed. Predictions were correlated with the experimental data. A flow visualization technique using helium filled soap bubbles was demonstrated.

Nitric Oxide PLIF Measurements in the Hypersonic Materials Environmental Test System (HYMETS)

NASA Technical Reports Server (NTRS)

Inman, Jennifer A.; Bathel, Brett F.; Johansen, Craig T.; Danehy, Paul M.; Jones, Stephen B.; Gragg, Jeffrey G.; Splinter, Scott C.; McRae, Colin D.

2013-01-01

Planar laser-induced fluorescence (PLIF) of naturally occurring nitric oxide (NO) has been used to obtain instantaneous flow visualization images, and to make both radial and axial velocity measurements in the HYMETS (Hypersonic Materials Environmental Test System) 400 kW arc-heated wind tunnel at NASA Langley Research Center. This represents the first application of NO PLIF flow visualization in HYMETS. Results are presented at selected facility run conditions, including some in a simulated Earth atmosphere (75% nitrogen, 20% oxygen, 5% argon) and others in a simulated Martian atmosphere (71% carbon dioxide, 24% nitrogen, 5% argon), for specific bulk enthalpies ranging from 6.5 MJ/kg to 18.4 MJ/kg. Flow visualization images reveal the presence of large scale unsteady flow structures, and indicate nitric oxide fluorescence signal over more than 70% of the core flow for specific bulk enthalpies below about 11 MJ/kg, but over less than 10% of the core flow for specific bulk enthalpies above about 16 MJ/kg. Axial velocimetry was performed using molecular tagging velocimetry (MTV). Axial velocities of about 3 km/s were measured along the centerline. Radial velocimetry was performed by scanning the wavelength of the narrowband laser and analyzing the resulting Doppler shift. Radial velocities of +/- 0.5 km/s were measured.

20 kHz toluene planar laser-induced fluorescence imaging of a jet in nearly sonic crossflow

NASA Astrophysics Data System (ADS)

Miller, V. A.; Troutman, V. A.; Mungal, M. G.; Hanson, R. K.

2014-10-01

This manuscript describes continuous, high-repetition-rate (20 kHz) toluene planar laser-induced fluorescence (PLIF) imaging in an expansion tube impulse flow facility. Cinematographic image sequences are acquired that visualize an underexpanded jet of hydrogen in Mach 0.9 crossflow, a practical flow configuration relevant to aerospace propulsion systems. The freestream gas is nitrogen seeded with toluene; toluene broadly absorbs and fluoresces in the ultraviolet, and the relatively high quantum yield of toluene produces large signals and high signal-to-noise ratios. Toluene is excited using a commercially available, frequency-quadrupled (266 nm), high-repetition-rate (20 kHz), pulsed (0.8-0.9 mJ per pulse), diode-pumped solid-state Nd:YAG laser, and fluorescence is imaged with a high-repetition-rate intensifier and CMOS camera. The resulting PLIF movie and image sequences are presented, visualizing the jet start-up process and the dynamics of the jet in crossflow; the freestream duration and a measure of freestream momentum flux steadiness are also inferred. This work demonstrates progress toward continuous PLIF imaging of practical flow systems in impulse facilities at kHz acquisition rates using practical, turn-key, high-speed laser and imaging systems.

Application of double-layered skin phantoms for optical flow imaging during laser tattoo treatments

NASA Astrophysics Data System (ADS)

Lee, Byeong-il; Song, Woosub; Kim, Hyejin; Kang, Hyun Wook

2016-05-01

The feasible application of double-layered skin phantoms was evaluated to identify artificial blood flow with a Doppler optical coherence tomography (DOCT) system for laser tattoo treatments. Polydimethylsiloxane (PDMS) was used to fabricate the artificial phantoms with flow channels embedded. A double-integrating sphere system with an inverse adding-doubling method quantified both the absorption and the reduced scattering coefficients for epidermis and dermis phantoms. Both OCT and caliper measurements confirmed the double-layered phantom structure (epidermis = 136 ± 17 µm vs. dermis = 3.0 ± 0.1 mm). The DOCT method demonstrated that high flow rates were associated with high image contrast, visualizing the position and the shape of the flow channel. Application of the channel-embedded skin phantoms in conjunction with DOCT can be a reliable technique to assess dynamic variations in the blood flow during and after laser tattoo treatments.

Hot gas ingestion test results of a two-poster vectored thrust concept with flow visualization in the NASA Lewis 9- by 15-foot low speed wind tunnel

NASA Technical Reports Server (NTRS)

Johns, Albert L.; Neiner, George; Bencic, Timothy J.; Flood, Joseph D.; Amuedo, Kurt C.

1990-01-01

A 9.2 percent scale STOVL hot gas ingestion model was tested in the NASA Lewis 9 x 15-foot Low-Speed Wind Tunnel. Flow visualization from the Phase 1 test program, which evaluated the hot ingestion phenomena and control techniques, is covered. The Phase 2 test program evaluated the hot gas ingestion phenomena at higher temperatures and used a laser sheet to investigate the flow field. Hot gas ingestion levels were measured for the several forward nozzle splay configurations and with flow control/life improvement devices (LIDs) which reduced the hot gas ingestion. The test was conducted at full scale nozzle pressure ratios and inlet Mach numbers. Results are presented over a range of nozzle pressure ratios at a 10 kn headwind velocity. The Phase 2 program was conducted at exhaust nozzle temperatures up to 1460 R and utilized a sheet laser system for flow visualization of the model flow field in and out of ground effects. The results reported are for nozzle exhaust temperatures up to 1160 R and contain the compressor face pressure and temperature distortions, the total pressure recovery, the inlet temperature rise, and the environmental effects of the hot gas. The environmental effects include the ground plane contours, the model airframe heating, and the location of the ground flow separation.

Effects of Passive Porosity on Interacting Vortex Flows At Supersonic Speeds

NASA Technical Reports Server (NTRS)

Erickson, Gary E.

2000-01-01

A wind tunnel experiment was conducted in the NASA Langley Research Center (LaRC) Unitary Plan Wind Tunnel (UPWT) to determine the effects of passive surface porosity on vortex flow interaction about a general research fighter configuration at supersonic speeds. Optical flow measurement and flow visualization techniques were used and included pressure-sensitive paint (PSP), schlieren, and laser vapor screen (LVS) These techniques were combined with force and moment and conventional electronically-scanned pressure (ESP) measurements to quantify and to visualize the effects of flow-through porosity applied to a wing leading-edge extension (LEX) mounted to a 65 deg cropped delta wing model.

Nitric Oxide PLIF Measurements in the Hypersonic Materials Environmental Test System (HYMETS)

NASA Technical Reports Server (NTRS)

Inman, Jennifer A.; Bathel, Brett F.; Johansen, Craig T.; Danehy, Paul M.; Jones, Stephen B.; Gragg, Jeffrey G.; Splinter, Scott C.

2011-01-01

A nonintrusive laser-based measurement system has been applied for the first time in the HYMETS (Hypersonic Materials Environmental Test System) 400 kW arc-heated wind tunnel at NASA Langley Research Center. Planar laser-induced fluorescence of naturally occurring nitric oxide (NO) has been used to obtain instantaneous flow visualization images, and to make both radial and axial velocity measurements. Results are presented at selected facility run conditions, including some in simulated Earth atmosphere (75% nitrogen, 20% oxygen, 5% argon) and others in simulated Martian atmosphere (71% carbon dioxide, 24% nitrogen, 5% argon), for bulk enthalpies ranging from 6.5 MJ/kg to 18.4 MJ/kg. Flow visualization images reveal the presence of large scale unsteady flow structures, and indicate nitric oxide fluorescence signal over more than 70% of the core flow for bulk enthalpies below about 11 MJ/kg, but over less than 10% of the core flow for bulk enthalpies above about 16 MJ/kg. Axial velocimetry was performed using molecular tagging velocimetry (MTV). Axial velocities of about 3 km/s were measured along the centerline. Radial velocimetry was performed by scanning the wavelength of the narrowband laser and analyzing the resulting Doppler shift. Radial velocities of 0.5km/s were measured.

Low-cost laser speckle contrast imaging of blood flow using a webcam.

PubMed

Richards, Lisa M; Kazmi, S M Shams; Davis, Janel L; Olin, Katherine E; Dunn, Andrew K

2013-01-01

Laser speckle contrast imaging has become a widely used tool for dynamic imaging of blood flow, both in animal models and in the clinic. Typically, laser speckle contrast imaging is performed using scientific-grade instrumentation. However, due to recent advances in camera technology, these expensive components may not be necessary to produce accurate images. In this paper, we demonstrate that a consumer-grade webcam can be used to visualize changes in flow, both in a microfluidic flow phantom and in vivo in a mouse model. A two-camera setup was used to simultaneously image with a high performance monochrome CCD camera and the webcam for direct comparison. The webcam was also tested with inexpensive aspheric lenses and a laser pointer for a complete low-cost, compact setup ($90, 5.6 cm length, 25 g). The CCD and webcam showed excellent agreement with the two-camera setup, and the inexpensive setup was used to image dynamic blood flow changes before and after a targeted cerebral occlusion.

Low-cost laser speckle contrast imaging of blood flow using a webcam

PubMed Central

Richards, Lisa M.; Kazmi, S. M. Shams; Davis, Janel L.; Olin, Katherine E.; Dunn, Andrew K.

2013-01-01

Laser speckle contrast imaging has become a widely used tool for dynamic imaging of blood flow, both in animal models and in the clinic. Typically, laser speckle contrast imaging is performed using scientific-grade instrumentation. However, due to recent advances in camera technology, these expensive components may not be necessary to produce accurate images. In this paper, we demonstrate that a consumer-grade webcam can be used to visualize changes in flow, both in a microfluidic flow phantom and in vivo in a mouse model. A two-camera setup was used to simultaneously image with a high performance monochrome CCD camera and the webcam for direct comparison. The webcam was also tested with inexpensive aspheric lenses and a laser pointer for a complete low-cost, compact setup ($90, 5.6 cm length, 25 g). The CCD and webcam showed excellent agreement with the two-camera setup, and the inexpensive setup was used to image dynamic blood flow changes before and after a targeted cerebral occlusion. PMID:24156082

Wave Propagation Through Inhomogeneities With Applications to Novel Sensing Techniques

NASA Technical Reports Server (NTRS)

Adamovsky, G.; Tokars, R.; Varga, D.; Floyd B.

2008-01-01

The paper describes phenomena observed as a result of laser pencil beam interactions with abrupt interfaces including aerodynamic shocks. Based on these phenomena, a novel flow visualization technique based on a laser scanning pencil beam is introduced. The technique reveals properties of light interaction with interfaces including aerodynamic shocks that are not seen using conventional visualization. Various configurations of scanning beam devices including those with no moving parts, as well as results of "proof-of-concept" tests, are included.

Application of holography to flow visualization

NASA Technical Reports Server (NTRS)

Lee, G.

1984-01-01

Laser holographic interferometry is being applied to many different types of aerodynamics problems. These include two and three dimensional flows in wind tunnels, ballistic ranges, rotor test chambers and turbine facilities. Density over a large field is measured and velocity, pressure, and mach number can be deduced.

Surface Tension Driven Convection Experiment (STDCE)

NASA Technical Reports Server (NTRS)

Ostrach, S.; Kamotani, Y.

1996-01-01

This document reports the results obtained from the Surface Tension Driven Convection Experiment (STDCE) conducted aboard the USML-1 Spacelab in 1992. The experiments used 10 cSt silicone oil placed in an open circular container that was 10 cm wide and 5 cm deep. Thermocapillary flow was induced by using either a cylindrical heater placed along the container centerline or by a CO2 laser. The tests were conducted under various power settings, laser beam diameters, and free surface shapes. Thermistors located at various positions in the test section recorded the temperature of the fluid, heater, walls, and air. An infrared imager was used to measure the free surface temperature. The flow field was studied by flow visualization and the data was analyzed by a PTV technique. The results from the flow visualization and the temperature measurements are compared with the numerical analysis that was conducted in conjunction with the experiment. The compared results include the experimental and numerical velocity vector plots, the streamline plots, the fluid temperature, and the surface temperature distribution.

Comparison of Mars Science Laboratory Reaction Control System Jet Computations With Flow Visualization and Velocimetry

NASA Technical Reports Server (NTRS)

Bathel, Brett F.; Danehy, Paul M.; Johansen, Craig T.; Ashcraft, Scott W.; Novak, Luke A.

2013-01-01

Numerical predictions of the Mars Science Laboratory reaction control system jets interacting with a Mach 10 hypersonic flow are compared to experimental nitric oxide planar laser-induced fluorescence data. The steady Reynolds Averaged Navier Stokes equations using the Baldwin-Barth one-equation turbulence model were solved using the OVERFLOW code. The experimental fluorescence data used for comparison consists of qualitative two-dimensional visualization images, qualitative reconstructed three-dimensional flow structures, and quantitative two-dimensional distributions of streamwise velocity. Through modeling of the fluorescence signal equation, computational flow images were produced and directly compared to the qualitative fluorescence data.

Orbiter BLT Flight Experiment Wind Tunnel Simulations: Nearfield Flowfield Imaging and Surface Thermography

NASA Technical Reports Server (NTRS)

Danehy, Paul M.; Ivey, Christoper B.; Barthel, Brett F.; Inman, Jennifer A.; Jones, Stephen B.; Watkins, Anthony N.; Goodman, Kyle Z.; McCrea, Andrew C.; Leighty, Bradley D.; Lipford, William K.;

Relationship between the Direction of Ophthalmic Artery Blood Flow and Ocular Microcirculation before and after Carotid Artery Stenting.

PubMed

Ishii, Masashi; Hayashi, Morito; Yagi, Fumihiko; Sato, Kenichiro; Tomita, Goji; Iwabuchi, Satoshi

2016-01-01

When internal carotid artery stenosis is accompanied by ocular ischemic syndrome, intervention is recommended to prevent irreversible visual loss. In this study, we used laser speckle flowgraphy to measure the ocular microcirculation in the optic nerve head before and after carotid artery stenting (CAS) of 40 advanced internal carotid stenosis lesions from 37 patients. The aim was to investigate the relationship between ocular microcirculation and the direction of ophthalmic artery blood flow obtained by angiography. We found that there was a significant increase in blood flow after CAS ( P = 0.003). Peak systolic velocity as an indicator of the rate of stenosis was also significantly higher in the group with retrograde/undetected flow of the ophthalmic artery than in the group with antegrade flow ( P = 0.002). In all cases where retrograde flow of the ophthalmic artery was observed before stenting, the flow changed to antegrade after stenting. Through the use of laser speckle flowgraphy, this study found that CAS can improve ocular microcirculation. Furthermore, while patients displaying retrograde flow of the ophthalmic artery before stenting have a poor prognosis, CAS corrected the flow to antegrade, suggesting that visual loss can be prevented by improving the ocular microcirculation.

Investigation of Turbulent Boundary-Layer Separation Using Laser Velocimetry

NASA Technical Reports Server (NTRS)

Modarress, D.; Johnson, D. A.

1979-01-01

Boundary-layer measurements realized by laser velocimetry are presented for a Much 2.9, two-dimensional, shock-wave/turbulent boundary-layer interaction containing an extensive region of separated flow. Mean velocity and turbulent intensity profiles were obtained from upstream of the interaction zone to downstream of the mean reattachment point. The superiority of the laser velocimeter technique over pressure sensors in turbulent separated flows is demonstrated by a comparison of the laser velocimeter data with results obtained from local pilot and static pressure measurements for the same flow conditions. The locations of the mean separation and reattachment points as deduced from the mean velocity measurements are compared to oil-now visualization results. Representative velocity probability density functions obtained in the separated now region are also presented. Critical to the success of this investigation were: the use of Bragg cell frequency shifting and artificial seeding of the now with submicron light-scattering particles.

Detailed flow-field measurements over a 75 deg swept delta wing

NASA Technical Reports Server (NTRS)

Kjelgaard, Scott O.; Sellers, William L., III

1990-01-01

Results from an experimental investigation documenting the flowfield over a 75 deg swept delta wing at an angle-of-attack of 20.5 deg are presented. Results obtained include surface flow visualization, off-body flow visualization, and detailed flowfield surveys for various Reynolds numbers. Flowfield surveys at Reynolds numbers of 0.5, 1.0, and 1.5 million based on the root chord were conducted with both a Pitot pressure probe and a 5-hole pressure probe; and 3-component laser velocimeter surveys were conducted at a Reynolds number of 1.0 million. The Pitot pressure surveys were obtained at 5 chordwise stations, the 5-hole probe surveys were obtained at 3 chordwise stations and the laser velocimeter surveys were obtained at one station. The results confirm the classical roll up of the flow into a pair of primary vortices over the delta wing. The velocity measurements indicate that Reynolds number has little effect on the global structure of the flowfield for the Reynolds number range investigated. Measurements of the non-dimensional axial velocity in the core of the vortex indicate a jet like flow with values greater than twice freestream. Comparisons between velocity measurements from the 5-hole pressure probe and the laser velocimeter indicate that the pressure probe does a reasonable job of measuring the flowfield quantities where the velocity gradients in the flowfield are low.

Flow visualization studies of transverse fuel injection patterns in a nonreacting Mach 2 combustor

NASA Technical Reports Server (NTRS)

Mcdaniel, J. C.

1987-01-01

Planar visualization images are recorded of transverse jet mixing in a supersonic combustor flowfield, without chemical reaction, using laser-induced fluorescence from iodine molecules. Digital image processing and three-dimensional display enable complete representations of fuel penetration boundary and shock surfaces corresponding to several injection geometries and pressures.

Laser-based volumetric flow visualization by digital color imaging of a spectrally coded volume.

PubMed

McGregor, T J; Spence, D J; Coutts, D W

2008-01-01

We present the framework for volumetric laser-based flow visualization instrumentation using a spectrally coded volume to achieve three-component three-dimensional particle velocimetry. By delivering light from a frequency doubled Nd:YAG laser with an optical fiber, we exploit stimulated Raman scattering within the fiber to generate a continuum spanning the visible spectrum from 500 to 850 nm. We shape and disperse the continuum light to illuminate a measurement volume of 20 x 10 x 4 mm(3), in which light sheets of differing spectral properties overlap to form an unambiguous color variation along the depth direction. Using a digital color camera we obtain images of particle fields in this volume. We extract the full spatial distribution of particles with depth inferred from particle color. This paper provides a proof of principle of this instrument, examining the spatial distribution of a static field and a spray field of water droplets ejected by the nozzle of an airbrush.

Measurement of velocity distribution and turbulence in a special wind tunnel using a laser Doppler velocimeter

NASA Astrophysics Data System (ADS)

Mueller, J.; Petersen, J. C.; Pilz, E.; Wiegand, H.

1981-06-01

The flow behavior in a jet mixing visualization chamber for turbulent fuel spray mixing with air under compression, e.g., at top dead center in diesel engines, was investigated with a laser Doppler velocimeter. The measurements were performed in two cuts in the profile perpendicular to the flow direction. The range of flow conditions in the measuring chamber was tested. The measurements were conducted with and without turbulence grids and shear flow grids behind the inlet nozzle. Wire grids did not enhance the turbulence in the measuring chamber. One of the tested shear flow grids produced shear flow as expected. A turbulence grid whose design was based on experimental results, produced a turbulence degree of up to 30% over the whole measuring cross section.

Laser Pencil Beam Based Techniques for Visualization and Analysis of Interfaces Between Media

NASA Technical Reports Server (NTRS)

Adamovsky, Grigory; Giles, Sammie, Jr.

1998-01-01

Traditional optical methods that include interferometry, Schlieren, and shadowgraphy have been used successfully for visualization and evaluation of various media. Aerodynamics and hydrodynamics are major fields where these methods have been applied. However, these methods have such major drawbacks as a relatively low power density and suppression of the secondary order phenomena. A novel method introduced at NASA Lewis Research Center minimizes disadvantages of the 'classical' methods. The method involves a narrow pencil-like beam that penetrates a medium of interest. The paper describes the laser pencil beam flow visualization methods in detail. Various system configurations are presented. The paper also discusses interfaces between media in general terms and provides examples of interfaces.

Use of schlieren methods to study gas flow in laser technology

NASA Astrophysics Data System (ADS)

Mrňa, Libor; Pavelka, Jan; Horník, Petr; Hrabovský, Jozef

2016-11-01

Laser technologies such as welding and cutting rely on process gases. We suggest to use schlieren imaging to visualize the gas flow during these processes. During the process of laser welding, the shielding gas flows to the welded area to prevent oxidation of the weld pool by surrounding air. The gas also interacts with hot plasma spurting from the key hole induced by the laser beam incident on the molten material. This interaction is quite complicated because hot plasma mixes with the cold shielding gas while the system is moving along the weld. Three shielding gases were used in the presented experiment: Ar, He and N2. Differences in dynamics of the flow are clearly visible on schlieren images. Moreover, high speed recording reveals a structure consisting of hot gas bubbles. We were also able to determine the velocity of the bubbles from the recording. During laser cutting, the process gas flows coaxially with the laser beam from the nozzle to remove the molten material out of the kerf. The gas flow is critical for the quality of the resulting edge of the cut. Schlieren method was used to study gas flow under the nozzle and then under the material being cut. This actually creates another slot nozzle. Due to the very low speed of flow below the material the schleiren method is already at the limit of its sensitivity. Therefore, it is necessary to apply a differential technique to increase the contrast. Distinctive widening of the flow shaped by the kerf was observed.

A study of the rotor wake of a small-scale rotor model in forward flight using laser light sheet flow visualization with comparisons to analytical models

NASA Technical Reports Server (NTRS)

Ghee, Terence A.; Elliott, Joe W.

1992-01-01

An experimental investigation was conducted in the 14 by 22 ft subsonic tunnel at NASA Langley Research Center to quantify the rotor wake behind a scale model helicopter rotor in forward flight (mu = 0.15 and 0.23) at one thrust level (C sub T = 0.0064). The rotor system used in the present test consisted of a four-bladed, fully articulated hub and utilized blades of rectangular planform with a NACA-0012 airfoil section. A laser light sheet, seeded with propylene glycol smoke, was used to visualize the flow in planes parallel and perpendicular to the freestream flow. Quantitative measurements of vortex location, vertical skew angle, and vortex particle void radius were obtained for vortices in the flow; convective velocities were obtained for blade tip vortices. Comparisons were made between the experimental results and the wake geometry generated by computational predictions. The results of these comparisons show that the interaction between wake vortex structures is an important consideration for correctly predicting the wake geometry.

Hot gas ingestion characteristics and flow visualization of a vectored thrust STOVL concept

NASA Technical Reports Server (NTRS)

Johns, Albert L.; Neiner, George H.; Bencic, Timothy J.; Flood, Joseph D.; Amuedo, Kurt C.; Strock, Thomas W.; Williams, Ben R.

1990-01-01

A 9.2 percent scale short takeoff and vertical landing (STOVL) hot gas ingestion model was designed and built by McDonnell Douglas Corporation (MCAIR) and tested in the NASA Lewis Research Center 9- by 15-Foot Low Speed Wind Tunnel (LSWT). Hot gas ingestion, the entrainment of heated engine exhaust into the inlet flow field, is a key development issue for advanced short takeoff and vertical landing aircraft. The Phase 1 test program, conducted by NASA Lewis and McDonnell Douglas Corporation, evaluated the hot ingestion phenomena and control techniques and Phase 2 test program which was conducted by NASA Lewis are both reported. The Phase 2 program was conducted at exhaust nozzles temperatures up to 1460 R and utilized a sheet laser system for flow visualization of the model flow field in and out of ground effects. Hot gas ingestion levels were measured for the several forward nozzle splay configurations and with flow control/lift improvement devices which reduced the hot gas ingestion. The model support system had four degrees of freedom, heated high pressure air for nozzle flow, and a suction system exhaust for inlet flow. The headwind (freestream) velocity for Phase 1 was varied from 8 to 90 kn, with primary data taken in the 8 to 23 kn headwind velocity range. Phase 2 headwind velocity varied from 10 to 23 kn. Results of both Phase 1 and 2 are presented. A description of the model, facility, a new model support system, and a sheet laser illumination system are also provided. Results are presented over a range of main landing gear height (model height) above the ground plane at a 10 kn headwind velocity. The results contain the compressor face pressure and temperature distortions, total pressure recovery, compressor face temperature rise, and the environmental effects of the hot gas. The environmental effects include the ground plane temperature and pressure distributions, model airframe heating, and the location of the ground flow separation. Results from the sheet laser flow visualization test are also shown.

Laser Beam Propagation Through Inhomogeneous Media with Shock-Like Profiles: Modeling and Computing

NASA Technical Reports Server (NTRS)

Adamovsky, Grigory; Ida, Nathan

1997-01-01

Wave propagation in inhomogeneous media has been studied for such diverse applications as propagation of radiowaves in atmosphere, light propagation through thin films and in inhomogeneous waveguides, flow visualization, and others. In recent years an increased interest has been developed in wave propagation through shocks in supersonic flows. Results of experiments conducted in the past few years has shown such interesting phenomena as a laser beam splitting and spreading. The paper describes a model constructed to propagate a laser beam through shock-like inhomogeneous media. Numerical techniques are presented to compute the beam through such media. The results of computation are presented, discussed, and compared with experimental data.

On the flow through the normal fetal aortic arc at late gestation

NASA Astrophysics Data System (ADS)

Pekkan, Kerem; Nourparvar, Paymon; Yerneni, Srinivasu; Dasi, Lakshmi; de Zelicourt, Diane; Fogel, Mark; Yoganathan, Ajit

2006-11-01

During the fetal stage, the aortic arc is a complex junction of great vessels (right and left ventricular outflow tracks (RVOT, LVOT), pulmonary arteries (PA), ductus, head-neck vessels, decending aorta (Dao)) delicately distributing the oxygenated blood flow to the lungs and the body -preferential to the brain. Experimental and computational studies are performed in idealized models of the fetal aorta to understand and visualize the unsteady hemodynamics. Unsteady in vitro flow, generated by two peristaltic pumps (RVOT and LVOT) is visualized with two colored dyes and a red laser in a rigid glass model with physiological diameters. Helical flow patterns at the PA's and ductal shunting to the Dao are visualized. Computational fluid dynamics of the same geometry is modeled using the commercial code Fidap with porous boundary conditions representing systemic and pulmonary resistances (˜400000 tetrahedral elements). Combined (RVOT+LVOT) average flow rates ranging from 1.9 to 2.1-L/min for 34 to 38-weeks gestation were simulated with the Reynolds and Womersly numbers (Dao) of 500 and 8. Computational results are compared qualitatively with the flow visualizations at this target flow condition. Understanding fetal hemodynamics is critical for congenital heart defects, tissue engineering, fetal cardiac MRI and surgeries.

Experimental studies on flow visualization and velocity field of compression ramp with different incoming boundary layers

NASA Astrophysics Data System (ADS)

Wu, Yu; Yi, Shi-He; He, Lin; Chen, Zhi; Zhu, Yang-Zhu

2014-11-01

Experimental studies which focus on flow visualization and the velocity field of a supersonic laminar/turbulent flow over a compression ramp were carried out in a Mach 3.0 wind tunnel. Fine flow structures and velocity field structures were obtained via NPLS (nanoparticle-tracer planar laser scattering) and PIV (particle image velocimetry) techniques, time-averaged flow structures were researched, and spatiotemporal evolutions of transient flow structures were analyzed. The flow visualization results indicated that when the ramp angles were 25°, a typical separation occurred in the laminar flow, some typical flow structures such as shock induced by the boundary layer, separation shock, reversed flow and reattachment shock were visible clearly. While a certain extent separation occurred in turbulent flow, the separation region was much smaller. When the ramp angles were 28°, laminar flow separated further, and the separation region expanded evidently, flow structures in the separation region were complex. While a typical separation occurred in turbulent flow, reversed flow structures were significant, flow structures in the separation region were relatively simple. The experimental results of velocity field were corresponding to flow visualization, and the velocity field structures of both compression ramp flows agreed with the flow structures well. There were three layered structures in the U component velocity, and the V component velocity appeared like an oblique “v”. Some differences between these two compression ramp flows can be observed in the velocity profiles of the shear layer and the shearing intensity.

Visualization and Analyses of Jet Structures from a Cluster-Type Linear Aerospike Nozzle

NASA Astrophysics Data System (ADS)

Niimi, Tomohide; Mori, Hideo; Okabe, Kazuki; Masai, Yusuke; Taniguchi, Mashio

Aerospike nozzles have been expected as a candidate for an engine of reusable space shuttles to respond to growing demand for rocket-launching and its cost reduction. In this study, the flow field structure in any cross sections around the linear-type aerospike nozzle are visualized and analyzed, using laser induced fluorescence (LIF) of NO seeded in the carrier gas N2. Since the flow field structure is affected mainly by the pressure ratio (P/P), the linear-type aerospike nozzle is set inside the vacuum chamber to carry out the experiments in the wide range of pressure ratios from 75 to 250. Flow fields are visualized in several cross-sections, demonstrating the complicated three-dimensional flow field structures. Pressure sensitive paint (PSP) of PtTFPP bound by poly(TMSP) is also applied successfully to measurement of the complicated pressure distribution on the spike surface.

Real-time blood flow visualization using the graphics processing unit

NASA Astrophysics Data System (ADS)

Yang, Owen; Cuccia, David; Choi, Bernard

2011-01-01

Laser speckle imaging (LSI) is a technique in which coherent light incident on a surface produces a reflected speckle pattern that is related to the underlying movement of optical scatterers, such as red blood cells, indicating blood flow. Image-processing algorithms can be applied to produce speckle flow index (SFI) maps of relative blood flow. We present a novel algorithm that employs the NVIDIA Compute Unified Device Architecture (CUDA) platform to perform laser speckle image processing on the graphics processing unit. Software written in C was integrated with CUDA and integrated into a LabVIEW Virtual Instrument (VI) that is interfaced with a monochrome CCD camera able to acquire high-resolution raw speckle images at nearly 10 fps. With the CUDA code integrated into the LabVIEW VI, the processing and display of SFI images were performed also at ~10 fps. We present three video examples depicting real-time flow imaging during a reactive hyperemia maneuver, with fluid flow through an in vitro phantom, and a demonstration of real-time LSI during laser surgery of a port wine stain birthmark.

Real-time blood flow visualization using the graphics processing unit

PubMed Central

Yang, Owen; Cuccia, David; Choi, Bernard

2011-01-01

Laser speckle imaging (LSI) is a technique in which coherent light incident on a surface produces a reflected speckle pattern that is related to the underlying movement of optical scatterers, such as red blood cells, indicating blood flow. Image-processing algorithms can be applied to produce speckle flow index (SFI) maps of relative blood flow. We present a novel algorithm that employs the NVIDIA Compute Unified Device Architecture (CUDA) platform to perform laser speckle image processing on the graphics processing unit. Software written in C was integrated with CUDA and integrated into a LabVIEW Virtual Instrument (VI) that is interfaced with a monochrome CCD camera able to acquire high-resolution raw speckle images at nearly 10 fps. With the CUDA code integrated into the LabVIEW VI, the processing and display of SFI images were performed also at ∼10 fps. We present three video examples depicting real-time flow imaging during a reactive hyperemia maneuver, with fluid flow through an in vitro phantom, and a demonstration of real-time LSI during laser surgery of a port wine stain birthmark. PMID:21280915

Visualization of liquid-assisted hard tissue ablation with a pulsed CO2 laser

NASA Astrophysics Data System (ADS)

Li, X. W.; Chen, C. G.; Zhang, X. Z.; Zhan, Z. L.; Xie, S. S.

2015-01-01

To investigate the characteristics of liquid-mediated hard tissue ablation induced by a pulsed CO2 laser with a wavelength of 10.6 μm, a high speed camera was used to monitor the interaction between water, tissue and laser irradiation. The results showed that laser irradiation can directly impact on tissue through a vapor channel formed by the leading part of the laser pulse. The ablation debris plays a key role in liquid-assisted laser ablation, having the ability to keep the vapor channel open to extend actuation time. The runoff effect induced by vortex convection liquid flow can remove the tissue that obstructs the effect of the next laser pulse.

Development of a Flow Visualization Technique for Transient Fluid Flow

DTIC Science & Technology

1992-12-31

high repetition rates, 2 to 10 kHz. The CW laser with a chopper wheel is limited to 4 kHz with a relatively large pulse width of 125 microseconds. The... four data points are in one CRAY word *I I* print«" bufloop %d width %d bufbytes %d image offset %ld xoffset %d \

Applicability of quantitative optical imaging techniques for intraoperative perfusion diagnostics: a comparison of laser speckle contrast imaging, sidestream dark-field microscopy, and optical coherence tomography

NASA Astrophysics Data System (ADS)

Jansen, Sanne M.; de Bruin, Daniel M.; Faber, Dirk J.; Dobbe, Iwan J. G. G.; Heeg, Erik; Milstein, Dan M. J.; Strackee, Simon D.; van Leeuwen, Ton G.

2017-08-01

Patient morbidity and mortality due to hemodynamic complications are a major problem in surgery. Optical techniques can image blood flow in real-time and high-resolution, thereby enabling perfusion monitoring intraoperatively. We tested the feasibility and validity of laser speckle contrast imaging (LSCI), optical coherence tomography (OCT), and sidestream dark-field microscopy (SDF) for perfusion diagnostics in a phantom model using whole blood. Microvessels with diameters of 50, 100, and 400 μm were constructed in a scattering phantom. Perfusion was simulated by pumping heparinized human whole blood at five velocities (0 to 20 mm/s). Vessel diameter and blood flow velocity were assessed with LSCI, OCT, and SDF. Quantification of vessel diameter was feasible with OCT and SDF. LSCI could only visualize the 400-μm vessel, perfusion units scaled nonlinearly with blood velocity. OCT could assess blood flow velocity in terms of inverse OCT speckle decorrelation time. SDF was not feasible to measure blood flow; however, for diluted blood the measurements were linear with the input velocity up to 1 mm/s. LSCI, OCT, and SDF were feasible to visualize blood flow. Validated blood flow velocity measurements intraoperatively in the desired parameter (mL·g-1) remain challenging.

Concentration Measurements in a Cold Flow Model Annular Combustor Using Laser Induced Fluorescence

NASA Technical Reports Server (NTRS)

Morgan, Douglas C.

1996-01-01

A nonintrusive concentration measurement method is developed for determining the concentration distribution in a complex flow field. The measurement method consists of marking a liquid flow with a water soluble fluorescent dye. The dye is excited by a two dimensional sheet of laser light. The fluorescent intensity is shown to be proportional to the relative concentration level. The fluorescent field is recorded on a video cassette recorder through a video camera. The recorded images are analyzed with image processing hardware and software to obtain intensity levels. Mean and root mean square (rms) values are calculated from these intensity levels. The method is tested on a single round turbulent jet because previous concentration measurements have been made on this configuration by other investigators. The previous results were used to comparison to qualify the current method. These comparisons showed that this method provides satisfactory results. 'Me concentration measurement system was used to measure the concentrations in the complex flow field of a model gas turbine annular combustor. The model annular combustor consists of opposing primary jets and an annular jet which discharges perpendicular to the primary jets. The mixing between the different jet flows can be visualized from the calculated mean and rms profiles. Concentration field visualization images obtained from the processing provide further qualitative information about the flow field.

Hot gas ingestion test results of a two-poster vectored thrust concept with flow visualization in the NASA Lewis 9- x 15-foot low speed wind tunnel

NASA Technical Reports Server (NTRS)

Johns, Albert L.; Neiner, George; Bencic, Timothy J.; Flood, Joseph D.; Amuedo, Kurt C.; Strock, Thomas W.

1990-01-01

A 9.2 percent scale Short Takeoff and Vertical Landing (STOVL) hot gas ingestion model was designed and built by McDonnell Douglas Corporation (MCAIR) and tested in the Lewis Research Center 9 x 15 foot Low Speed Wind Tunnel (LSWT). Hot gas ingestion, the entrainment of heated engine exhaust into the inlet flow field, is a key development issure for advanced short takeoff and vertical landing aircraft. Flow visualization from the Phase 1 test program, which evaluated the hot ingestion phenomena and control techniques, is covered. The Phase 2 test program evaluated the hot gas ingestion phenomena at higher temperatures and used a laser sheet to investigate the flow field. Hot gas ingestion levels were measured for the several forward nozzle splay configurations and with flow control/life improvement devices (LIDs) which reduced the hot gas ingestion. The model support system had four degrees of freedom - pitch, roll, yaw, and vertical height variation. The model support system also provided heated high-pressure air for nozzle flow and a suction system exhaust for inlet flow. The test was conducted at full scale nozzle pressure ratios and inlet Mach numbers. Test and data analysis results from Phase 2 and flow visualization from both Phase 1 and 2 are documented. A description of the model and facility modifications is also provided. Headwind velocity was varied from 10 to 23 kn. Results are presented over a range of nozzle pressure ratios at a 10 kn headwind velocity. The Phase 2 program was conducted at exhaust nozzle temperatures up to 1460 R and utilized a sheet laser system for flow visualization of the model flow field in and out of ground effects. The results reported are for nozzle exhaust temperatures up to 1160 R. These results will contain the compressor face pressure and temperature distortions, the total pressure recovery, the inlet temperature rise, and the environmental effects of the hot gas. The environmental effects include the ground plane contours, the model airframe heating, and the location of the ground flow separation.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kiss, L.I.; Bui, R.T.; Charette, A.

The flow structure inside round furnaces with various numbers of burners, burner arrangement, and exit conditions has been studied experimentally with the purpose of improving the flow conditions and the resulting heat transfer. Small-scale transparent models were built according to the laws of geometric and dynamic similarity. Various visualization and experimental techniques were applied. The flow pattern in the near-surface regions was visualized by the fluorescent minituft and popcorn techniques; the flow structure in the bulk was analyzed by smoke injection and laser sheet illumination. For the study of the transient effects, high-speed video photography was applied. The effects ofmore » the various flow patterns, like axisymmetric and rotational flow, on the magnitude and uniformity of the residence time, as well as on the formation of stagnation zones, were discussed. Conclusions were drawn and have since been applied for the improvement of furnace performance.« less

The development of laser speckle or particle image displacement velocimetry. Part 1: The role of photographic parameters

NASA Technical Reports Server (NTRS)

Lourenco, L. M. M.; Krothapalli, A.

1987-01-01

One of the difficult problems in experimental fluid dynamics remains the determination of the vorticity field in fluid flows. Recently, a novel velocity measurement technique, commonly known as Laser Speckle or Particle Image Displacement Velocimetry became available. This technique permits the simultaneous visualization of the 2 dimensional streamline pattern in unsteady flows and the quantification of the velocity field. The main advantage of this new technique is that the whole 2 dimensional velocity field can be recorded with great accuracy and spatial resolution, from which the instantaneous vorticity field can be easily obtained. A apparatus used for taking particle displacement images is described. Local coherent illumination by the probe laser beam yielded Young's fringes of good quality at almost every location of the flow field. These fringes were analyzed and the velocity and vorticity fields were derived. Several conclusions drawn are discussed.

Visualization of gas flow and diffusion in porous media

PubMed Central

Kaiser, Lana G.; Meersmann, Thomas; Logan, John W.; Pines, Alexander

2000-01-01

The transport of gases in porous materials is a crucial component of many important processes in science and technology. In the present work, we demonstrate how magnetic resonance microscopy with continuous flow laser-polarized noble gases makes it possible to “light up” and thereby visualize, with unprecedented sensitivity and resolution, the dynamics of gases in samples of silica aerogels and zeolite molecular sieve particles. The “polarization-weighted” images of gas transport in aerogel fragments are correlated to the diffusion coefficient of xenon obtained from NMR pulsed-field gradient experiments. The technique provides a unique means of studying the combined effects of flow and diffusion in systems with macroscopic dimensions and microscopic internal pore structure. PMID:10706617

Toluene laser-induced fluorescence imaging of compressible flows in an expansion tube

NASA Astrophysics Data System (ADS)

Miller, V. A.; Gamba, M.; Mungal, M. G.; Hanson, R. K.; Mohri, K.; Schulz, C.

2011-11-01

Laser-induced fluorescence (LIF) imaging using toluene as a tracer molecule has been developed for high-speed, low-to-moderate enthalpy conditions in the Stanford 6-inch Expansion Tube. The approach is demonstrated on three canonical compressible flow configurations: (i) supersonic flow over a 20° wedge, (ii) around a cylinder, and (iii) a supersonic boundary layer. Under constant-pressure conditions, toluene LIF offers unique sensitivity to temperature and can therefore be used as an accurate thermometry diagnostic for supersonic flows; on the other hand, for variable-pressure flow fields (e.g., flow around a blunt body), toluene LIF imaging is demonstrated to be an effective flow visualization tool. The three configurations selected demonstrate the diagnostic in these two capacities. For all configurations considered in the study, toluene (0.6% by volume) is seeded into a nitrogen freestream at a Mach number ~ 2.2, T ~ 500K, and p ~ 1.5 bar. A frequency-quadrupled pulsed Nd:YAG laser is used to excite the tracer, and the resulting fluorescence is captured by an ICCD camera. Synthetic fluorescence signals from CFD solutions of each case have been computed and compare favorably to measured signals. Sponsored by DoE PSAAP at Stanford University.

Emergence of power-law scalings in shock-driven mixing transition

NASA Astrophysics Data System (ADS)

Vorobieff, Peter; Wayne, Patrick; Olmstead, Dell; Simons, Dylan; Truman, C. Randall; Kumar, Sanjay

2016-11-01

We present an experimental study of transition to turbulence due to shock-driven instability evolving on an initially cylindrical, diffuse density interface between air and a mixture of sulfur hexafluoride (SF6) and acetone. The plane of the shock is at an initial angle θ with the axis of the heavy-gas cylinder. We present the cases of planar normal (θ = 0) and oblique (θ =20°) shock interaction with the initial conditions. Flow is visualized in two perpendicular planes with planar laser-induced fluorescence (PLIF) triggered in acetone with a pulsed ultraviolet laser. Statistics of the flow are characterized in terms of the second-order structure function of the PLIF intensity. As instabilities in the flow evolve, the structure functions begin to develop power-law scalings, at late times manifesting over a range of scales spanning more than two orders of magnitude. We discuss the effects of the initial conditions on the emergence of these scalings, comparing the fully three-dimensional case (oblique shock interaction) with the quasi-two-dimensional case (planar normal shock interaction). We also discuss the flow anisotropy apparent in statistical differences in data from the two visualization planes. This work is funded by NNSA Grant DE-NA0002913.

Flow visualization of mast-mounted-sight/main rotor aerodynamic interactions

NASA Technical Reports Server (NTRS)

Ghee, Terence A.; Kelley, Henry L.

1993-01-01

Flow visualization tests were conducted on a 27 percent-scale AH-64 attack helicopter model fitted with various mast-mounted-sight configurations in an attempt to identify the cause of adverse vibration encountered during full-scale flight tests of an Apache/Longbow configuration. The tests were conducted at the NASA Langley Research Center in the 14- by 22-Foot Subsonic Tunnel. A symmetric and an asymmetric mast-mounted-sight oriented at several skew angles were tested at forward and rearward flight speeds of 30 and 45 knots. A laser light sheet seeded with vaporized propylene glycol was used to visualize the wake of the sight in planes parallel and perpendicular to the freestream flow. Analysis of the flow visualization data identified the frequency of the wake shed from the sight, the angle-of-attack at the sight, and the location where the sight wake crossed the rotor plane. Differences in wake structure were observed between the various sight configurations and slew angles. Postulations into the cause of the adverse vibration found in flight test are given along with considerations for future tests.

High-speed imaging of submerged jet: visualization analysis using proper orthogonality decomposition

NASA Astrophysics Data System (ADS)

Liu, Yingzheng; He, Chuangxin

2016-11-01

In the present study, the submerged jet at low Reynolds numbers was visualized using laser induced fluoresce and high-speed imaging in a water tank. Well-controlled calibration was made to determine linear dependency region of the fluoresce intensity on its concentration. Subsequently, the jet fluid issuing from a circular pipe was visualized using a high-speed camera. The animation sequence of the visualized jet flow field was supplied for the snapshot proper orthogonality decomposition (POD) analysis. Spatio-temporally varying structures superimposed in the unsteady fluid flow were identified, e.g., the axisymmetric mode and the helical mode, which were reflected from the dominant POD modes. The coefficients of the POD modes give strong indication of temporal and spectral features of the corresponding unsteady events. The reconstruction using the time-mean visualization and the selected POD modes was conducted to reveal the convective motion of the buried vortical structures. National Natural Science Foundation of China.

Reperfusion of occluded branch retinal arteries by transluminal Nd:YAG laser embolysis combined with intravenous thrombolysis of urokinase

PubMed Central

Chai, Fang; Du, Shanshuang; Zhao, Xiquan

2017-01-01

Purpose: To report successful treatment with transluminal Nd:YAG laser embolysis (TYE) combined with urokinase thrombolysis for reperfusion of occluded branch retinal arteries with visible emboli. Methods: A total of 34 eyes from 34 patients with acute, severe vision loss secondary to a branch retinal artery occlusion with visible emboli and retinal whitening were examined. Each patient was administered TYE therapy, which focused on the embolus, using an ocular contact lens; a 0.3–0.9 mJ laser pulse was delivered directly and gradually according to the reaction. Fundus photographs and fundus fluorescein angiography (FFA) were obtained before and immediately after the laser treatment. All patients received urokinase thrombolysis therapy drops intravenously for 5 days at 10–20 u/d. The follow-up period ranged from 6 to 14 months after therapy. The morphological characteristics of FFA associated with obstruction recovery of arterial fluorescence filling and visual function were analyzed. Results: After TYE therapy, FFA examinations showed that the retinal artery and its branches exhibited completely restored blood flow without obstruction in 13 eyes, accounting for 38.2% of the cases. The blood flow was mostly recovered in 11 eyes (32.4% of patients). FFA examinations following the combined intravenous urokinase thrombolysis therapy showed that the retinal artery and its branches exhibited completely restored blood flow after obstruction in 16 eyes (47.1% of patients). The blood flow was mostly recovered in 15 eyes (44.1% of patients). Conclusion: TYE combined with urokinase thrombolysis is effective for reperfusion of occluded branch retinal arteries and improving visual recovery in patients with visible emboli. PMID:29162667

Time resolved PIV and flow visualization of 3D sheet cavitation

NASA Astrophysics Data System (ADS)

Foeth, E. J.; van Doorne, C. W. H.; van Terwisga, T.; Wieneke, B.

2006-04-01

Time-resolved PIV was applied to study fully developed sheet cavitation on a hydrofoil with a spanwise varying angle of attack. The hydrofoil was designed to have a three-dimensional cavitation pattern closely related to propeller cavitation, studied for its adverse effects as vibration, noise, and erosion production. For the PIV measurements, fluorescent tracer particles were applied in combination with an optical filter, in order to remove the reflections of the laser lightsheet by the cavitation. An adaptive mask was developed to find the interface between the vapor and liquid phase. The velocity at the interface of the cavity was found to be very close to the velocity predicted by a simple streamline model. For a visualization of the global flow dynamics, the laser beam was expanded and used to illuminate the entire hydrofoil and cavitation structure. The time-resolved recordings reveal the growth of the attached cavity and the cloud shedding. Our investigation proves the viability of accurate PIV measurements around developed sheet cavitation. The presented results will further be made available as a benchmark for the validation of numerical simulations of this complicated flow.

Laser-optical and numerical Research of the flow inside the lubricating gap of a journal bearing model

NASA Astrophysics Data System (ADS)

Nobis, M.; Stücke, P.; Schmidt, M.; Riedel, M.

2013-04-01

The laser-optical research of the flow inside the lubricating gap of a journal bearing model is one important task in a larger overall project. The long-term objective is the development of an easy-to-work calculation tool which delivers information about the causes and consequences of cavitation processes in hydrodynamically lubricated journal bearings. Hence, it will be possible to find statements for advantageous and disadvantageous geometrical shapes of the bushings. In conclusion such a calculation tool can provide important insights for the construction and design of future journal bearings. Current design programs are based on a two-dimensional approach for the lubricating gap. The first dimension is the breath of the bearing and the second dimension is the circumferential direction of the bearing. The third dimension, the expansion of the gap in radial direction, will be neglected. Instead of an exact resolution of the flow pattern inside the gap, turbulence models are in use. Past studies on numerical and experimental field have shown that inside the lubricating gap clearly organized and predominantly laminar flow structures can be found. Thus, for a detailed analysis of the reasons and effects of cavitation bubbles, a three-dimensional resolution of the lubricating gap is inevitable. In addition to the qualitative evaluation of the flow with visualization experiments it is possible to perform angle-based velocity measurements inside the gap with the help of a triggered Laser-Doppler- Velocimeter (LDV). The results of these measurements are used to validate three-dimensional CFD flow simulations, and to optimize the numerical mesh structure and the boundary conditions. This paper will present the experimental setup of the bearing model, some exemplary results of the visualization experiments and LDV measurements as well as a comparison between experimental and numerical results.

Flow Visualization by Elastic Light Scattering in the Boundary Layer of a Supersonic Flow

NASA Technical Reports Server (NTRS)

Herring, G. C.; Hillard, Mervin E., Jr.

2000-01-01

We demonstrate instantaneous flow visualization of the boundary layer region of a Mach 2.5 supersonic flow over a flat plate that is interacting with an impinging shock wave. Tests were performed in the Unitary Plan Wind Tunnel (UPWT) at NASA Langley Research Center. The technique is elastic light scattering using 10-nsec laser pulses at 532 nm. We emphasize that no seed material of any kind, including water (H2O), is purposely added to the flow. The scattered light comes from a residual impurity that normally exists in the flow medium after the air drying process. Thus, the technique described here differs from the traditional vapor-screen method, which is typically accomplished by the addition of extra H2O vapor to the airflow. The flow is visualized with a series of thin two-dimensional light sheets (oriented perpendicular to the streamwise direction) that are located at several positions downstream of the leading edge of the model. This geometry allows the direct observation of the unsteady flow structure in the spanwise dimension of the model and also allows the indirect observation of the boundary layer growth in the streamwise dimension.

An LDA (Laser-Doppler Anemometry) investigation of three-dimensional normal shock wave boundary-layer interactions

NASA Technical Reports Server (NTRS)

Chriss, R. M.; Hingst, W. R.; Strazisar, A. J.; Keith, T. G., Jr.

1989-01-01

Nonintrusive measurements were made of a normal shock wave/boundary layer interaction. Two dimensional measurements were made throughout the interaction region while 3-D measurements were made in the vicinity of the shock wave. The measurements were made in the corner of the test section of a continuous supersonic wind tunnel in which a normal shock wave had been stabilized. Laser Doppler Anemometry, surface pressure measurement and flow visualization techniques were employed for two freestream Mach number test cases: 1.6 and 1.3. The former contained separated flow regions and a system of shock waves. The latter was found to be far less complicated. The results define the flow field structure in detail for each case.

Experimental and computational investigation of the NASA Low-Speed Centrifugal Compressor flow field

NASA Technical Reports Server (NTRS)

Hathaway, M. D.; Chriss, R. M.; Wood, J. R.; Strazisar, A. J.

1992-01-01

An experimental and computational investigation of the NASA Low-Speed Centrifugal Compressor (LSCC) flow field has been conducted using laser anemometry and Dawes' 3D viscous code. The experimental configuration consists of a backswept impeller followed by a vaneless diffuser. Measurements of the three-dimensional velocity field were acquired at several measurement planes through the compressor. The measurements describe both the throughflow and secondary velocity field along each measurement plane. In several cases the measurements provide details of the flow within the blade boundary layers. Insight into the complex flow physics within centrifugal compressors is provided by the computational analysis, and assessment of the CFD predictions is provided by comparison with the measurements. Five-hole probe and hot-wire surveys at the inlet and exit to the rotor as well as surface flow visualization along the impeller blade surfaces provide independent confirmation of the laser measurement technique.

Dual laser optical system and method for studying fluid flow

NASA Technical Reports Server (NTRS)

Owen, R. B.; Witherow, W. K. (Inventor)

1983-01-01

A dual laser optical system and method is disclosed for visualization of phenomena in transport substances which induce refractive index gradients such as fluid flow and pressure and temperature gradients in fluids and gases. Two images representing mutually perpendicular components of refractive index gradients may be viewed simultaneously on screen. Two lasers having wave lengths in the visible range but separated by about 1000 angstroms are utilized to provide beams which are collimated into a beam containing components of the different wave lengths. The collimated beam is passed through a test volume of the transparent substance. The collimated beam is then separated into components of the different wave lengths and focused onto a pair of knife edges arranged mutually perpendicular to produce and project images onto the screen.

Imaging of molecular hydrogen and oxygen by single and two-photon fluorescence using laser and flashlamp sources

NASA Technical Reports Server (NTRS)

Diskin, Glenn S.; Lempert, Walter R.; Miles, Richard B.; Kumar, Vinod; Glesk, Ivan

1991-01-01

Two flow visualization techniques, i.e., simultaneous two-dimensional fluorescence imaging of H2 and O2 in a diffusion flame, and quasi-linear fluorescence imaging of O2, are presented. The first uses an injection-locked argon-fluoride excimer laser and a partial overlap of a two-photon ground state absorption in H2 with a single photon absorption from a vibrational level in O2. The second uses a simple, high-intensity ultraviolet flashlamp which provides a flux of photons in the 180-195 nm range, sufficient to produce a quasi-one-dimensional fluorescence image of hot/room temperature oxygen. Both techniques do not require that a seed material be introduced into the flow, they can image major flow constituents, and provide an instantaneous snapshot of the flow.

Experimental investigation of shock-cell noise reduction for dual-stream nozzles in simulated flight comprehensive data report. Volume 2: Laser velocimeter data, static pressures and shadowgraph photos

NASA Technical Reports Server (NTRS)

Yamamoto, K.; Janardan, B. A.; Brausch, J. F.; Hoerst, D. J.; Price, A. O.

1984-01-01

Parameters which contribute to supersonic jet shock noise were investigated for the purpose of determining means to reduce such noise generation to acceptable levels. Six dual-stream test nozzles with varying flow passage and plug closure designs were evaluated under simulated flight conditions in an anechoic chamber. All nozzles had combined convergent-divergent or convergent flow passages. Mean velocity and turbulence velocity measurements of 25 selected flow conditions were performed employing a laser Doppler velocimeter. Static pressure measurements were made to define the actual convergence-divergence condition. Test point definition, tabulation of aerodynamic test conditions, velocity histograms, and shadowgraph photographs are presented. Flow visualization through shadowgraph photography can contribute to the development of an analytical prediction model for shock noise from coannular plug nozzles.

The effects of stabilizing and destabilizing longitudinal curvature on the structure of turbulent, two-stream mixing layers

NASA Technical Reports Server (NTRS)

Plesniak, Michael W.; Johnston, J. P.

1989-01-01

The construction and development of the multi-component traversing system and associated control hardware and software are presented. A hydrogen bubble/laser sheet flow visualization technique was developed to visually study the characteristics of the mixing layers. With this technique large-scale rollers arising from the Taylor-Gortler instability and its interaction with the primary Kelvin-Helmholtz structures can be studied.

Nonintrusive Temperature and Velocity Measurements in a Hypersonic Nozzle Flow

NASA Technical Reports Server (NTRS)

OByrne, S.; Danehy, P. M.; Houwing, A. F. P.

2002-01-01

Distributions of nitric oxide vibrational temperature, rotational temperature and velocity have been measured in the hypersonic freestream at the exit of a conical nozzle, using planar laser-induced fluorescence. Particular attention has been devoted to reducing the major sources of systematic error that can affect fluorescence tempera- ture measurements, including beam attenuation, transition saturation effects, laser mode fluctuations and transition choice. Visualization experiments have been performed to improve the uniformity of the nozzle flow. Comparisons of measured quantities with a simple one-dimensional computation are made, showing good agreement between measurements and theory given the uncertainty of the nozzle reservoir conditions and the vibrational relaxation rate.

Study of Injection of Helium into Supersonic Air Flow Using Rayleigh Scattering

NASA Technical Reports Server (NTRS)

Seaholtz, Richard G.; Buggele, Alvin E.

1997-01-01

A study of the transverse injection of helium into a Mach 3 crossflow is presented. Filtered Rayleigh scattering is used to measure penetration and helium mole fraction in the mixing region. The method is based on planar molecular Rayleigh scattering using an injection-seeded, frequency-doubled ND:YAG pulsed laser and a cooled CCD camera. The scattered light is filtered with an iodine absorption cell to suppress stray laser light. Preliminary data are presented for helium mole fraction and penetration. Flow visualization images obtained with a shadowgraph and wall static pressure data in the vicinity of the injection are also presented.

NAVO MSRC Navigator. Spring 2003

DTIC Science & Technology

2003-01-01

computational model run on the IBM POWER4 (MARCELLUS) in support of the Airborne Laser Challenge Project II. The data were visualized using Alias|Wavefront Maya...Turbulence in a Jet Stream in the Airborne Laser Context High Performance Computing 11 Largest NAVO MSRC System Becomes Even Bigger and Better 11 Using the smp...centimeters (cm). The resolution requirement to resolve the microjets and the flow outside in the combustor is too severe for any single numerical method

OZONE CONTACTOR FLOW VISUALIZATION AND CHARACTERIZATION USING 3-DIMENSIONAL LASER INDUCED FLUORESCENCE

EPA Science Inventory

Hydrodynamics of ozone contactors have a crucial impact on efficient inactivation of pathogens such as Cryptosporidium as well as control of disinfection byproducts such as bromate. Improper mixing behaviors including short-circuiting, internal recirculation and presence...

Experimental Study of Saddle Point of Attachment in Laminar Juncture Flow

NASA Technical Reports Server (NTRS)

Coon, Michael D.; Tobak, Murray

1995-01-01

An experimental study of laminar horseshoe vortex flows upstream of a cylinder/flat plate juncture has been conducted to verify the existence of saddle-point-of-attachment topologies. In the classical depiction of this flowfield, a saddle point of separation exists on the flat plate upstream of the cylinder, and the boundary layer separates from the surface. Recent computations have indicated that the topology may actually involve a saddle point of attachment on the surface and additional singular points in the flow. Laser light sheet flow visualizations have been performed on the symmetry plane and crossflow planes to identify the saddle-point-of-attachment flowfields. The visualizations reveal that saddle-point-of-attachment topologies occur over a range of Reynolds numbers in both single and multiple vortex regimes. An analysis of the flow topologies is presented that describes the existence and evolution of the singular points in the flowfield.

Experimental study of the velocity field on a delta wing

NASA Technical Reports Server (NTRS)

Payne, F. M.; Ng, T. T.; Nelson, R. C.

1987-01-01

An experimental study of the leading edge vortices on delta wings at large angles of incidence is presented. A combination of flow visualization, seven-hole pressure probe surveys and laser velocimeter measurements were used to study the leading edge vortex formation and breakdown for a set of delta wings. The delta wing models were thin flat plates with sharp leading edges having sweep angles of 70, 75, 80, and 85 degrees. The flow structure was examined for angles of incidence from 10 to 40 degrees and chord Reynolds numbers from 85,000 to 640,000. Vortex breakdown was observed on all the wings tested. Both bubble and spiral modes of breakdown were observed. The visualization and wake survey data shows that when vortex breakdown occurs the core flow transforms abruptly from a jet-like flow to a wake-like flow. The result also revealed that probe induced vortex breakdown was more steady than the natural breakdown.

A qualitative and quantitative laser-based computer-aided flow visualization method. M.S. Thesis, 1992 Final Report

NASA Technical Reports Server (NTRS)

Canacci, Victor A.; Braun, M. Jack

1994-01-01

The experimental approach presented here offers a nonintrusive, qualitative and quantitative evaluation of full field flow patterns applicable in various geometries in a variety of fluids. This Full Flow Field Tracking (FFFT) Particle Image Velocimetry (PIV) technique, by means of particle tracers illuminated by a laser light sheet, offers an alternative to Laser Doppler Velocimetry (LDV), and intrusive systems such as Hot Wire/Film Anemometry. The method makes obtainable the flow patterns, and allows quantitative determination of the velocities, accelerations, and mass flows of an entire flow field. The method uses a computer based digitizing system attached through an imaging board to a low luminosity camera. A customized optical train allows the system to become a long distance microscope (LDM), allowing magnifications of areas of interest ranging up to 100 times. Presented in addition to the method itself, are studies in which the flow patterns and velocities were observed and evaluated in three distinct geometries, with three different working fluids. The first study involved pressure and flow analysis of a brush seal in oil. The next application involved studying the velocity and flow patterns in a cowl lip cooling passage of an air breathing aircraft engine using water as the working fluid. Finally, the method was extended to a study in air to examine the flows in a staggered pin arrangement located on one side of a branched duct.

Investigation of inner aerodynamics of the four-vortex furnace model

NASA Astrophysics Data System (ADS)

Anufriev, I. S.; Shadrin, E. Yu; Sharypov, O. V.

2018-03-01

The internal aerodynamics of a perspective vortex furnace chamber of a pulverized coal boiler with a diagonal arrangement of burners is studied using the non-contact optical method of flow diagnostics. The results of laser Doppler anemometry, characterizing the complex spatial structure of a swirling flow in an isothermal laboratory model of the furnace device, are presented. The velocity distribution in the vortex chamber volume is obtained, and the flow structure in the form of four conjugate closed vortices with curved axes is visualized.

An experimental investigation of vortex breakdown on a delta wing

NASA Technical Reports Server (NTRS)

Payne, F. M.; Nelson, R. C.

1986-01-01

An experimental investigation of vortex breakdown on delta wings at high angles is presented. Thin delta wings having sweep angles of 70, 75, 80 and 85 degrees are being studied. Smoke flow visualization and the laser light sheet technique are being used to obtain cross-sectional views of the leading edge vortices as they break down. At low tunnel speeds (as low as 3 m/s) details of the flow, which are usually imperceptible or blurred at higher speeds, can be clearly seen. A combination of lateral and longitudinal cross-sectional views provides information on the three dimensional nature of the vortex structure before, during and after breakdown. Whereas details of the flow are identified in still photographs, the dynamic characteristics of the breakdown process were recorded using high speed movies. Velocity measurements were obtained using a laser Doppler anemometer with the 70 degree delta wing at 30 degrees angle of attack. The measurements show that when breakdown occurs the core flow transforms from a jet-like flow to a wake-like flow.

An Overview of Brazilian Developments in Beamed Energy Aerospace Propulsion and Vehicle Performance Control

DOE Office of Scientific and Technical Information (OSTI.GOV)

Minucci, M. A. S.

Beamed energy propulsion and beamed energy vehicle performance control concepts are equally promising and challenging. In Brazil, the two concepts are being currently investigated at the Prof Henry T Nagamatsu Laboratory of Aerothermodynamics and Hypersonics, of the Institute for Advanced Studies--IEAv, in collaboration with the Rensselaer Polytechnic Institute--RPI, Troy, NY, and the United States Air force Research Laboratory-AFRL. Until recently, only laser energy addition for hypersonic flow control was being investigated at the Laboratory using a 0.3 m nozzle exit diameter hypersonic shock tunnel, T2, and two 7 joule CO{sub 2} TEA lasers. Flow visualization, model pressure and heat fluxmore » measurements of the laser energy addition perturbed flow around a model were produced as a result of this joint IEAv-RPI investigation. Presently, with the participation of AFRL and the newly commissioned 0.6 m. nozzle exit diameter hypersonic shock tunnel, T3, a more ambitious project is underway. Two 400 Joule Lumonics 620 CO{sub 2} TEA lasers will deliver a 20 cm X 25 cm propulsive laser beam to a complete laser propelled air breather/rocket hypersonic engine, located inside T3 test section. Schlieren photographs of the flow inside de engine as well as surface and heat flux measurements will be performed for free stream Mach numbers ranging from 6 to 25. The present paper discusses past, present and future Brazilian activities on beamed energy propulsion and related technologies.« less

An Overview of Brazilian Developments in Beamed Energy Aerospace Propulsion and Vehicle Performance Control

NASA Astrophysics Data System (ADS)

Minucci, M. A. S.

2008-04-01

Beamed energy propulsion and beamed energy vehicle performance control concepts are equally promising and challenging. In Brazil, the two concepts are being currently investigated at the Prof Henry T Nagamatsu Laboratory of Aerothermodynamics and Hypersonics, of the Institute for Advanced Studies—IEAv, in collaboration with the Rensselaer Polytechnic Institute—RPI, Troy, NY, and the United States Air force Research Laboratory-AFRL. Until recently, only laser energy addition for hypersonic flow control was being investigated at the Laboratory using a 0.3 m nozzle exit diameter hypersonic shock tunnel, T2, and two 7 joule CO2 TEA lasers. Flow visualization, model pressure and heat flux measurements of the laser energy addition perturbed flow around a model were produced as a result of this joint IEAv-RPI investigation. Presently, with the participation of AFRL and the newly commissioned 0.6 m. nozzle exit diameter hypersonic shock tunnel, T3, a more ambitious project is underway. Two 400 Joule Lumonics 620 CO2 TEA lasers will deliver a 20 cm X 25 cm propulsive laser beam to a complete laser propelled air breather/rocket hypersonic engine, located inside T3 test section. Schlieren photographs of the flow inside de engine as well as surface and heat flux measurements will be performed for free stream Mach numbers ranging from 6 to 25. The present paper discusses past, present and future Brazilian activities on beamed energy propulsion and related technologies.

Experimental research on crossing shock wave boundary layer interactions

NASA Astrophysics Data System (ADS)

Settles, G. S.; Garrison, T. J.

1994-10-01

An experimental research effort of the Penn State Gas Dynamics Laboratory on the subject of crossing shock wave boundary layer interactions is reported. This three year study was supported by AFOSR Grant 89-0315. A variety of experimental techniques were employed to study the above phenomena including planar laser scattering flowfield visualization, kerosene lampblack surface flow visualization, laser-interferometer skin friction surveys, wall static pressure measurements, and flowfield five-hole probe surveys. For a model configuration producing two intersecting shock waves, measurements were made for a range of oblique shock strengths at freestream Mach numbers of 3.0 and 3.85. Additionally, measurements were made at Mach 3.85 for a configuration producing three intersecting waves. The combined experimental dataset was used to formulate the first detailed flowfield models of the crossing-shock and triple-shock wave/boundary layer interactions. The structure of these interactions was found to be similar over a broad range of interaction strengths and is dominated by a large, separated, viscous flow region.

Comparison of PLIF and CFD Results for the Orion CEV RCS Jets

NASA Technical Reports Server (NTRS)

Ivey, Christopher B.; Danehy, Paul M.; Bathel, Brett F.; Dyakonov, Artem A.; Inman, Jennifer A.; Jones, Stephen B.

2011-01-01

Nitric-oxide planar laser-induced fluorescence (NO PLIF) was used to visualize and measure centerline streamwise velocity of the Orion Crew Exploration Vehicle (CEV) Reaction Control System (RCS) Jets at NASA Langley Research Center's 31-Inch Mach 10 Air wind tunnel. Fluorescence flow visualizations of pitch, roll, and yaw RCS jets were obtained using different plenum pressures and wind tunnel operating stagnation pressures. For two yaw RCS jet test cases, the PLIF visualizations were compared to computational flow imaging (CFI) images based on Langley Aerothermal Upwind Relaxation Algorithm (LAURA) computational fluid dynamics (CFD) simulations of the flowfield. For the same test cases, the streamwise velocity measurements were compared to CFD. The CFD solution, while showing some unphysical artifacts, generally agree with the experimental measurements.

An Experimental Investigation of Fluid Flow and Heating in Various Resonance Tube Modes

NASA Technical Reports Server (NTRS)

Sarohia, V.; Back, L. H.; Roschke, E. J.; Pathasarathy, S. P.

1976-01-01

Experiments have been performed to study resonance phenomena in tubes excited by underexpanded jet flows. This investigation comprised the following: Study of the various resonance tube modes under a wide range of nozzle pressure, spacing between nozzle and tube mouth, and different tube length; the effects of these modes on the endwall pressure and gas temperature; flow visualization of both jet and tube flows by spark shadowgraph technique; and measurement of wave speed inside the tube by the laser-schlieren techniques. An extensive study of the free-jet flow was undertaken to explain important aspects of various modes of operation of resonance tube flows.

Ground-Based Measurements of the Wake Vortex Characteristics of a B-747 Aircraft in Various Configurations

DOT National Transportation Integrated Search

1978-12-01

A Boeing 747 aircraft flew 54 passes at low altitude over ground based sensors. Vortex velocities were measured by a laser Doppler velocimeter, an array of monostatic acoustic sounders, and an array of propeller anemometers. Flow visualization of the...

Unified Application of Vapor Screen Flow Visualization and Pressure Sensitive Paint Measurement Techniques to Vortex- and Shock Wave-Dominated Flow Fields

NASA Technical Reports Server (NTRS)

Erickson, Gary E.

2010-01-01

Laser vapor screen (LVS) flow visualization and pressure sensitive paint (PSP) techniques were applied in a unified approach to wind tunnel testing of slender wing and missile configurations dominated by vortex flows and shock waves at subsonic, transonic, and supersonic speeds. The off-surface cross-flow patterns using the LVS technique were combined with global PSP surface static pressure mappings to characterize the leading-edge vortices and shock waves that coexist and interact at high angles of attack. The synthesis of LVS and PSP techniques was also effective in identifying the significant effects of passive surface porosity and the presence of vertical tail surfaces on the flow topologies. An overview is given of LVS and PSP applications in selected experiments on small-scale models of generic slender wing and missile configurations in the NASA Langley Research Center (NASA LaRC) Unitary Plan Wind Tunnel (UPWT) and 8-Foot Transonic Pressure Tunnel (8-Foot TPT).

Unified Application Vapor Screen Flow Visualization and Pressure Sensitive Paint Measurement Techniques to Vortex- and Shock Wave-Dominated Flow Fields

NASA Technical Reports Server (NTRS)

Erickson, Gary E.

2008-01-01

Laser vapor screen (LVS) flow visualization and pressure sensitive paint (PSP) techniques were applied in a unified approach to wind tunnel testing of slender wing and missile configurations dominated by vortex flows and shock waves at subsonic, transonic, and supersonic speeds. The off-surface cross-flow patterns using the LVS technique were combined with global PSP surface static pressure mappings to characterize the leading-edge vortices and shock waves that coexist and interact at high angles of attack (alpha). The synthesis of LVS and PSP techniques was also effective in identifying the significant effects of passive surface porosity and the presence of vertical tail surfaces on the flow topologies. An overview is given of LVS and PSP applications in selected experiments on small-scale models of generic slender wing and missile configurations in the NASA Langley Research Center (NASA LaRC) Unitary Plan Wind Tunnel (UPWT) and 8-Foot Transonic Pressure Tunnel (8-Foot TPT).

Optimization of the cleaning process on a pilot filtration setup for waste water treatment accompanied by flow visualization

NASA Astrophysics Data System (ADS)

Bílek, Petr; Hrůza, Jakub

2018-06-01

This paper deals with an optimization of the cleaning process on a liquid flat-sheet filter accompanied by visualization of the inlet side of a filter. The cleaning process has a crucial impact on the hydrodynamic properties of flat-sheet filters. Cleaning methods avoid depositing of particles on the filter surface and forming a filtration cake. Visualization significantly helps to optimize the cleaning methods, because it brings new overall view on the filtration process in time. The optical method, described in the article, enables to see flow behaviour in a thin laser sheet on the inlet side of a tested filter during the cleaning process. Visualization is a strong tool for investigation of the processes on filters in details and it is also possible to determine concentration of particles after an image analysis. The impact of air flow rate, inverse pressure drop and duration on the cleaning mechanism is investigated in the article. Images of the cleaning process are compared to the hydrodynamic data. The tests are carried out on a pilot filtration setup for waste water treatment.

Simultaneous visualization of transonic buffet on a rocket faring model using unsteady PSP measurement and Schlieren method

NASA Astrophysics Data System (ADS)

Nakakita, K.

2017-02-01

Simultaneous visualization technique of the combination of the unsteady Pressure-Sensitive Paint and the Schlieren measurement was introduced. It was applied to a wind tunnel test of a rocket faring model at the JAXA 2mx2m transonic wind tunnel. Quantitative unsteady pressure field was acquired by the unsteady PSP measurement, which consisted of a high-speed camera, high-power laser diode, and so on. Qualitative flow structure was acquired by the Schlieren measurement using a high-speed camera and Xenon lamp with a blue optical filter. Simultaneous visualization was achieved 1.6 kfps frame rate and it gave the detailed structure of unsteady flow fields caused by the unsteady shock wave oscillation due to shock-wave/boundary-layer interaction around the juncture between cone and cylinder on the model. Simultaneous measurement results were merged into a movie including surface pressure distribution on the rocket faring and spatial structure of shock wave system concerning to transonic buffet. Constructed movie gave a timeseries and global information of transonic buffet flow field on the rocket faring model visually.

Visualization of Flowfield Modification by RCS Jets on a Capsule Entry Vehicle

NASA Technical Reports Server (NTRS)

Danehy, P. M.; Inman, J. A.; Alderfer, D. W.; Buck, G. M.; Schwartz, R.

2008-01-01

Nitric oxide planar laser-induced fluorescence (NO PLIF) has been used to visualize the flow on the aft-body of an entry capsule having an activated RCS jet in NASA Langley Research Center's 31-Inch Mach 10 wind tunnel facility. A capsule shape representative of the Apollo command module was tested. These tests were performed to demonstrate the ability of the PLIF method to visualize RCS jet flow while providing some preliminary input to NASA's Orion Vehicle design team. Two different RCS nozzle designs - conical and contoured - were tested. The conical and contoured nozzles had area ratios of 13.4 and 22.5 respectively. The conical nozzle had a half-angle of 10 . Low- and high-Reynolds number cases were investigated by changing the tunnel stagnation pressure from 350 psi to 1300 psi, resulting in freestream Reynolds numbers of 0.56 and 1.8 million per foot respectively. For both of these cases, three different jet plenum pressures were tested (nominally 56, 250 and 500 psi). A single angle-of-attack was investigated (24 degrees). NO PLIF uses an ultraviolet laser sheet to interrogate a slice in the flow containing seeded NO; this UV light excites fluorescence from the NO molecules which is detected by a high-speed digital camera. The system has spatial resolution of about 200 microns (2 pixel blurring) and has flow-stopping time resolution (approximately 1 microsecond). NO was seeded into the flow two different ways. First, the RCS jet fluid was seeded with approximately 1-5% NO, with the balance N2. This allowed observation of the shape, structure and trajectory of the RCS jets. Visualizations of both laminar and turbulent flow jet features were obtained. Visualizations were obtained with the tunnel operating at Mach 10 and also with the test section held at a constant pressure similar to the aftbody static pressure (0.04 psi) obtained during tunnel runs. These two conditions are called "tunnel on" and "tunnel off" respectively. Second, the forebody flow was seeded with a very low flowrate (<100 standard cubic centimeters per minute) of pure NO. This trace gas was entrained into and allowed visualization of the shear layer forming between the expansion fan on the shoulder of the model and the recirculating separated flow in the wake of the model. This shear layer was observed to be laminar in the absence of the RCS jet operation and turbulent above a certain RCS jet flowrate. Furthermore, the operation of the RCS jet is seen to push the shear layer out away from the model, with a higher jet pressures resulting in larger deflections. Figures show some data from this test, partially processed. In the final paper, these images will be processed and rendered on a three dimensional visualization of the test hardware for clearer visualization and interpretation of the flowfields.

Flow Visualization in Supersonic Turbulent Boundary Layers.

NASA Astrophysics Data System (ADS)

Smith, Michael Wayne

This thesis is a collection of novel flow visualizations of two different flat-plate, zero pressure gradient, supersonic, turbulent boundary layers (M = 2.8, Re _theta ~ 82,000, and M = 2.5, Re_ theta ~ 25,000, respectively). The physics of supersonic shear flows has recently drawn increasing attention with the renewed interest in flight at super and hypersonic speeds. This work was driven by the belief that the study of organized, Reynolds -stress producing turbulence structures will lead to improved techniques for the modelling and control of high-speed boundary layers. Although flow-visualization is often thought of as a tool for providing qualitative information about complex flow fields, in this thesis an emphasis is placed on deriving quantitative results from image data whenever possible. Three visualization techniques were applied--'selective cut-off' schlieren, droplet seeding, and Rayleigh scattering. Two experiments employed 'selective cut-off' schlieren. In the first, high-speed movies (40,000 fps) were made of strong density gradient fronts leaning downstream at between 30^circ and 60^ circ and travelling at about 0.9U _infty. In the second experiment, the same fronts were detected with hot-wires and imaged in real time, thus allowing the examination of the density gradient fronts and their associated single-point mass -flux signals. Two experiments employed droplet seeding. In both experiments, the boundary layer was seeded by injecting a stream of acetone through a single point in the wall. The acetone is atomized by the high shear at the wall into a 'fog' of tiny (~3.5mu m) droplets. In the first droplet experiment, the fog was illuminated with copper-vapor laser sheets of various orientations. The copper vapor laser pulses 'froze' the fog motion, revealing a variety of organized turbulence structures, some with characteristic downstream inclinations, others with large-scale roll-up on the scale of delta. In the second droplet experiment, high-speed movies were made of the fog under general illumination, thus providing information about the streamwise evolution of the structures seen in the planar stills. Rayleigh scattering from a laser sheet was used to create instantaneous density cross-sections in the M = 2.5 boundary layer. The Rayleigh scattering experiment represents the first measurement of the instantaneous 2-D field of an intrinsic fluid property in any boundary layer. Imaged by an intensified UV camera, scattering from the Argon-Fluoride laser (193 nm) revealed density structures with sharp interfaces between high and low-density fluid. These pictures were also used to generated quantitative turbulence information. Density pdf profiles, intermittency values, density correlations, and structure shape data were derived with standard digital image-processing techniques.

Laser speckle imaging allows real-time intraoperative blood flow assessment during neurosurgical procedures.

PubMed

Hecht, Nils; Woitzik, Johannes; König, Susanne; Horn, Peter; Vajkoczy, Peter

2013-07-01

Currently, there is no adequate technique for intraoperative monitoring of cerebral blood flow (CBF). To evaluate laser speckle imaging (LSI) for assessment of relative CBF, LSI was performed in 30 patients who underwent direct surgical revascularization for treatment of arteriosclerotic cerebrovascular disease (ACVD), Moyamoya disease (MMD), or giant aneurysms, and in 8 control patients who underwent intracranial surgery for reasons other than hemodynamic compromise. The applicability and sensitivity of LSI was investigated through baseline perfusion and CO2 reactivity testing. The dynamics of LSI were assessed during bypass test occlusion and flow initiation procedures. Laser speckle imaging permitted robust (pseudo-) quantitative assessment of relative microcirculatory flow and standard bypass grafting resulted in significantly higher postoperative baseline perfusion values in ACVD and MMD. The applicability and sensitivity of LSI was shown by a significantly reduced CO2 reactivity in ACVD (9.6±9%) and MMD (8.5±8%) compared with control (31.2±5%; P<0.0001). In high- and intermediate-flow bypass patients, LSI was characterized by a dynamic real-time response to acute perfusion changes and ultimately confirmed a sufficient flow substitution through the bypass graft. Thus, LSI can be used for sensitive and continuous, non-invasive real-time visualization and measurement of relative cortical CBF in excellent spatial-temporal resolution.

Toward the development of a low-cost laser Doppler module for ophthalmic microscopes

NASA Astrophysics Data System (ADS)

Cattini, Stefano; Rovati, Luigi

2012-03-01

A laser Doppler module easily integrated into a commercial ophthalmic microscope is proposed. Such setup adds flow measurement capability to standard visual inspection of the fundus. The proposed instrument may provide important clinical information such as the detection of vessel occlusion provided by surgical treatments (i.e. photocoagulation). The measuring system is based on a self-mixing laser diode Doppler flowmeter (SM-DF). Reduced costs, easy implementation and small size represent the main features of SM-DF. Moreover, this technique offers the advantage to have the excitation and measurement beams spatially overlapped, thus both overcoming the alignment difficulty of traditional laser Doppler flowmeter and, well fitting with to limited optical aperture of the pupil. Thanks to an on-board DSP-microcontroller, the optoelectronic module directly estimates the blood flow; USB connection and an ad-hoc developed user-friendly software interface allow displaying the result on a personal computer. Preliminary test demonstrates the applicability of the proposed measuring system.

A user's guide to the Langley 16- by 24-inch water tunnel

NASA Technical Reports Server (NTRS)

Pendergraft, Odis C., Jr.; Neuhart, Dan H.; Kariya, Timmy T.

1992-01-01

The Langley 16 x 24 inch Water Tunnel is described in detail, along with all the supporting equipment used in its operation as a flow visualization test facility. These include the laser and incandescent lighting systems; and the photographic, video, and laser fluorescence anemometer systems used to make permanent records of the test results. This facility is a closed return water tunnel capable of test section velocities from 0 to 0.75 feet per second with flow through the 16 x 24 inch test section in a downward (vertical) direction. The velocity normally used for testing is 0.25 feet per second where the most uniform flow occurs, and is slow enough to easily observe flow phenomena such as vortex flow with the unaided eye. An overview is given of the operational characteristics, procedures, and capabilities of the water tunnel to potential users of the facility so that they may determine if the facility meets their needs for a planned study.

Experimental and computational investigation of the NASA low-speed centrifugal compressor flow field

NASA Technical Reports Server (NTRS)

Hathaway, Michael D.; Chriss, Randall M.; Wood, Jerry R.; Strazisar, Anthony J.

1993-01-01

An experimental and computational investigation of the NASA Lewis Research Center's low-speed centrifugal compressor (LSCC) flow field was conducted using laser anemometry and Dawes' three-dimensional viscous code. The experimental configuration consisted of a backswept impeller followed by a vaneless diffuser. Measurements of the three-dimensional velocity field were acquired at several measurement planes through the compressor. The measurements describe both the throughflow and secondary velocity field along each measurement plane. In several cases the measurements provide details of the flow within the blade boundary layers. Insight into the complex flow physics within centrifugal compressors is provided by the computational fluid dynamics analysis (CFD), and assessment of the CFD predictions is provided by comparison with the measurements. Five-hole probe and hot-wire surveys at the inlet and exit to the impeller as well as surface flow visualization along the impeller blade surfaces provided independent confirmation of the laser measurement technique. The results clearly document the development of the throughflow velocity wake that is characteristic of unshrouded centrifugal compressors.

In-vivo visualization of melanoma tumor microvessels and blood flow velocity changes accompanying tumor growth

NASA Astrophysics Data System (ADS)

Ishida, Hiroki; Hachiga, Tadashi; Andoh, Tsugunobu; Akiguchi, Shunsuke

2012-11-01

We demonstrate that using micro multipoint laser Doppler velocimetry (μ-MLDV) for noninvasive in-vivo imaging of blood vessels is useful for diagnosing malignant melanomas by comparison with visual diagnosis by dermoscopy. The blood flow velocity in microvessels varied during growth of melanomas transplanted in mouse ears. Mouse ears were observed by μ-MLDV up to 16 days after transplantation. The blood flow velocity in the tumor increased with increasing time and reached maximum of 4.5 mm/s at 9 days, which is more than twice that prior to transplantation. After 12 days, when the lesion had grown to an area of 6.6 mm2, we observed the formation of new blood vessels in the tumor. Finally, when the lesion had an area of 18 mm2 after 16 days, the flow velocity in the tumor decreased to approximately 3.2 mm/s.

Control of Acoustics and Store Separation in a Cavity in Supersonic Flow

DTIC Science & Technology

2005-02-01

laser -based flow visualization experiments on the FSU cavity for different microjet pressures. The details of the experiments are given in Zhuang, et. al...developed that rigorously explains the role of leading edge microjets in cavity noise suppression and predicts the magnitude of noise reduction for a...given control input (that is the steady pressure at which the microjets are fired). The model is validated through comparison of its noise reduction

Mass and momentum turbulent transport experiments with confined swirling coaxial jets

NASA Technical Reports Server (NTRS)

Roback, R.; Johnson, B. V.

1983-01-01

Swirling coaxial jets mixing downstream, discharging into an expanded duct was conducted to obtain data for the evaluation and improvement of turbulent transport models currently used in a variety of computational procedures throughout the combustion community. A combination of laser velocimeter (LV) and laser induced fluorescence (LIF) techniques was employed to obtain mean and fluctuating velocity and concentration distributions which were used to derive mass and momentum turbulent transport parameters currently incorporated into various combustor flow models. Flow visualization techniques were also employed to determine qualitatively the time dependent characteristics of the flow and the scale of turbulence. The results of these measurements indicated that the largest momentum turbulent transport was in the r-z plane. Peak momentum turbulent transport rates were approximately the same as those for the nonswirling flow condition. The mass turbulent transport process for swirling flow was complicated. Mixing occurred in several steps of axial and radial mass transport and was coupled with a large radial mean convective flux. Mixing for swirling flow was completed in one-third the length required for nonswirling flow.

Planar Rayleigh scattering and laser-induced fluorescence for visualization of a hot, Mach 2 annular air jet

NASA Technical Reports Server (NTRS)

Balla, R. Jeffrey

1994-01-01

Planar Rayleigh scattering (PRS) and planar laser-induced fluorescence (PLIF) were used to investigate the vitiated air component of a coaxial hydrogen/vitiated air nonpremixed turbulent jet flame that is ejected at a Mach number of 2. All experiments were performed with a xenon chloride tunable excimer laser. Planar information for both techniques was obtained using laser sheets 6 cm high, 5 cm wide, and 300 micron thick. In this flow field, the effective Rayleigh cross section of the components in the vitiated air was assumed to be independent of composition. Therefore, the PRS technique produced signals which were proportional to total density. When the flow field was assumed to be at a known and uniform pressure, the PRS signal data for the vitiated air could be converted to temperature information. Also, PLIF images were generated by probing the OH molecule. These images contain striation patterns attributed to small localized instantaneous temperature nonuniformities. The results from the PLIF and PRS techniques were used to show that this flow field contains a nongaseous component, most likely liquid water that can be reduced by increasing the settling chamber wall temperature.

PLIF Study of Mars Science Laboratory Capsule Reaction Control System Jets

NASA Technical Reports Server (NTRS)

Johansen, C. T.; Danehy, P. M.; Ashcraft, S. W.; Bathel, B. F.; Inman, J. A.; Jones, S. B.

2011-01-01

Nitric-oxide planar laser-induced fluorescence (NO PLIF) was used to visualize the flow in the wake of a Mars Science Lab (MSL) entry capsule with activated reaction control system (RCS) jets in NASA Langley Research Center s 31-Inch Mach 10 Air Tunnel facility. Images were processed using the Virtual Diagnostics Interface (ViDI) method, which brings out the three-dimensional nature of the flow visualization data while showing the relative location of the data with respect to the model. Comparison of wind-on and wind-off results illustrates the effect that the hypersonic crossflow has on the trajectory and structure of individual RCS jets. The visualization and comparison of both single and multiple activated RCS jets indicate low levels of jet-jet interaction. Quantitative streamwise velocity was also obtained via NO PLIF molecular tagging velocimetry (MTV).

PLIF Study of Mars Science Laboratory Capsule Reaction Control System Jets

NASA Technical Reports Server (NTRS)

Johansen, C. T.; Danehy, P. M.; Ashcraft, S. W.; Bathel, B. F.; Inman, J. A.; Jones, S. B.

2011-01-01

Nitric-oxide planar laser-induced fluorescence (NO PLIF) was used to visualize the flow in the wake of a Mars Science Lab (MSL) entry capsule with activated reaction control system (RCS) jets in NASA Langley Research Center's 31-Inch Mach 10 Air Tunnel facility. Images were processed using the Virtual Diagnostics Interface (ViDI) method, which brings out the three-dimensional nature of the flow visualization data while showing the relative location of the data with respect to the model. Comparison of wind-on and wind-off results illustrates the effect that the hypersonic crossflow has on the trajectory and structure of individual RCS jets. The visualization and comparison of both single and multiple activated RCS jets indicate low levels of jet-jet interaction. Quantitative streamwise velocity was also obtained via NO PLIF molecular tagging velocimetry (MTV).

Visualization study of counterflow in superfluid 4He using metastable helium molecules.

PubMed

Guo, W; Cahn, S B; Nikkel, J A; Vinen, W F; McKinsey, D N

2010-07-23

Heat is transferred in superfluid 4He via a process known as thermal counterflow. It has been known for many years that above a critical heat current the superfluid component in this counterflow becomes turbulent. It has been suspected that the normal-fluid component may become turbulent as well, but experimental verification is difficult without a technique for visualizing the flow. Here we report a series of visualization studies on the normal-fluid component in a thermal counterflow performed by imaging the motion of seeded metastable helium molecules using a laser-induced-fluorescence technique. We present evidence that the flow of the normal fluid is indeed turbulent at relatively large velocities. Thermal counterflow in which both components are turbulent presents us with a theoretically challenging type of turbulent behavior that is new to physics.

The art and science of flow control - case studies using flow visualization methods

NASA Astrophysics Data System (ADS)

Alvi, F. S.; Cattafesta, L. N., III

2010-04-01

Active flow control (AFC) has been the focus of significant research in the last decade. This is mainly due to the potentially substantial benefits it affords. AFC applications range from the subsonic to the supersonic (and beyond) regime for both internal and external flows. These applications are wide and varied, such as controlling flow transition and separation over various external components of the aircraft to active management of separation and flow distortion in engine components and over turbine and compressor blades. High-speed AFC applications include control of flow oscillations in cavity flows, supersonic jet screech, impinging jets, and jet-noise control. In this paper we review some of our recent applications of AFC through a number of case studies that illustrate the typical benefits as well as limitations of present AFC methods. The case studies include subsonic and supersonic canonical flowfields such as separation control over airfoils, control of supersonic cavity flows and impinging jets. In addition, properties of zero-net mass-flux (ZNMF) actuators are also discussed as they represent one of the most widely studied actuators used for AFC. In keeping with the theme of this special issue, the flowfield properties and their response to actuation are examined through the use of various qualitative and quantitative flow visualization methods, such as smoke, shadowgraph, schlieren, planar-laser scattering, and Particle image velocimetry (PIV). The results presented here clearly illustrate the merits of using flow visualization to gain significant insight into the flow and its response to AFC.

Stereotactic CO2 laser therapy for hydrocephalus

NASA Astrophysics Data System (ADS)

Kozodoy-Pins, Rebecca L.; Harrington, James A.; Zazanis, George A.; Nosko, Michael G.; Lehman, Richard M.

1994-05-01

A new fiber-optic delivery system for CO2 radiation has been used to successfully treat non-communicating hydrocephalus. This system consists of a hollow sapphire waveguide employed in the lumen of a stereotactically-guided neuroendoscope. CO2 gas flows through the bore of the hollow waveguide, creating a path for the laser beam through the cerebrospinal fluid (CSF). This delivery system has the advantages of both visualization and guided CO2 laser radiation without the same 4.3 mm diameter scope. Several patients with hydrocephalus were treated with this new system. The laser was used to create a passage in the floor of the ventricle to allow the flow of CSF from the ventricles to the sub-arachnoid space. Initial postoperative results demonstrated a relief of the clinical symptoms. Long-term results will indicate if this type of therapy will be superior to the use of implanted silicone shunts. Since CO2 laser radiation at 10.6 micrometers is strongly absorbed by the water in tissue and CSF, damage to tissue surrounding the lesion with each laser pulse is limited. The accuracy and safety of this technique may prove it to be an advantageous therapy for obstructive hydrocephalus.

Laboratory Facilities and Measurement Techniques for Beamed-Energy-Propulsion Experiments in Brazil

NASA Astrophysics Data System (ADS)

de Oliveira, Antonio Carlos; Chanes Júnior, José Brosler; Cordeiro Marcos, Thiago Victor; Pinto, David Romanelli; Santos Vilela, Renan Guilherme; Barros Galvão, Victor Alves; Mantovani, Arthur Freire; da Costa, Felipe Jean; dos Santos Assenção, José Adeildo; dos Santos, Alberto Monteiro; de Paula Toro, Paulo Gilberto; Sala Minucci, Marco Antonio; da Silveira Rêgo, Israel; Salvador, Israel Irone; Myrabo, Leik N.

2011-11-01

Laser propulsion is an innovative concept of accessing the space easier and cheaper where the propulsive energy is beamed to the aerospace vehicle in flight from ground—or even satellite-based high-power laser sources. In order to be realistic about laser propulsion, the Institute for Advanced Studies of the Brazilian Air Force in cooperation with the United States Air Force and the Rensselaer Polytechnic Institute are seriously investigating its basic physics mechanisms and engineering aspects at the Henry T. Hamamatsu Laboratory of Hypersonic and Aerothermodynamics in São José dos Campos, Brazil. This paper describes in details the existing facilities and measuring systems such as high-power laser devices, pulsed-hypersonic wind tunnels and high-speed flow visualization system currently utilized in the laboratory for experimentation on laser propulsion.

Effects of hyper +Gz acceleration on cardiovascular function, visual evoked potentials and cerebral blood flow in anesthetized rats.

PubMed

Matsunami, K; Satake, H; Konishi, T

1998-07-01

Sustained hyper-gravity acceleration, particularly along the long axis of the body of animals or man (Gz), produces significant mal-effects on subjects, and hence it has been well studied, The most common syndromes of Gz application were cardio-vascular de-conditioning, and black-out, red-out, and loss of consciousness, which finally lead subjects into death. However, in most previous studies, the duration of applied Gz was rather short. In the present experiments, we can use longer duration of 1000 seconds. In addition, recent technological innovation make it possible to record directly local cerebral blood flow at a target cortical area with a Laser Doppler flow meter. We used this innovated method to measure local cerebral blood flow of rats in relation to visual evoked potentials (VEPs) under hyper-Gz acceleration. Also we recorded cardio-vascular parameters like heart rate from ECG, systolic and diastolic blood pressure and correlated them with cerebral blood flow and VEPs.

Active control of jet flowfields

NASA Astrophysics Data System (ADS)

Kibens, Valdis; Wlezien, Richard W.

1987-06-01

Passive and active control of jet shear layer development were investigated as mechanisms for modifying the global characteristics of jet flowfields. Slanted and stepped indeterminate origin (I.O.) nozzles were used as passive, geometry-based control devices which modified the flow origins. Active control techniques were also investigated, in which periodic acoustic excitation signals were injected into the I.O. nozzle shear layers. Flow visualization techniques based on a pulsed copper-vapor laser were used in a phase-conditioned image acquisition mode to assemble optically averaged sets of images acquired at known times throughout the repetition cycle of the basic flow oscillation period. Hot wire data were used to verify the effect of the control techniques on the mean and fluctuating flow properties. The flow visualization images were digitally enhanced and processed to show locations of prominent vorticity concentrations. Three-dimensional vortex interaction patterns were assembled in a format suitable for movie mode on a graphic display workstation, showing the evolution of three-dimensional vortex system in time.

Convective flows in enclosures with vertical temperature or concentration gradients

NASA Technical Reports Server (NTRS)

Wang, L. W.; Chai, A. T.; Sun, D. J.

1988-01-01

The transport process in the fluid phase during the growth of a crystal has a profound influence on the structure and quality of the solid phase. In vertical growth techniques the fluid phase is often subjected to vertical temperature and concentration gradients. The main objective is to obtain more experimental data on convective flows in enclosures with vertical temperature or concentration gradients. Among actual crystal systems the parameters vary widely. The parametric ranges studied for mass transfer are mainly dictated by the electrochemical system employed to impose concentration gradients. Temperature or concentration difference are maintained between two horizontal end walls. The other walls are kept insulated. Experimental measurements and observations were made of the heat transfer or mass transfer, flow patterns, and the mean and fluctuating temperature distribution. The method used to visualize the flow pattern in the thermal cases is an electrochemical pH-indicator method. Laser shadowgraphs are employed to visualize flow patterns in the solutal cases.

Convective flows in enclosures with vertical temperature or concentration gradients

NASA Technical Reports Server (NTRS)

Wang, L. W.; Chai, A. T.; Sun, D. J.

1989-01-01

The transport process in the fluid phase during the growth of a crystal has a profound influence on the structure and quality of the solid phase. In vertical growth techniques the fluid phase is often subjected to vertical temperature and concentration gradients. The main objective is to obtain more experimental data on convective flows in enclosures with vertical temperature or concentration gradients. Among actual crystal systems the parameters vary widely. The parametric ranges studied for mass transfer are mainly dictated by the electrochemical system employed to impose concentration gradients. Temperature or concentration difference are maintained between two horizontal end walls. The other walls are kept insulated. Experimental measurements and observations were made of the heat transfer or mass transfer, flow patterns, and the mean and fluctuating temperature distribution. The method used to visualize the flow pattern in the thermal cases is an electrochemical pH-indicator method. Laser shadowgraphs are employed to visualize flow patterns in the solutal cases.

Photoacoustic imaging velocimetry for flow-field measurement.

PubMed

Ma, Songbo; Yang, Sihua; Xing, Da

2010-05-10

We present the photoacoustic imaging velocimetry (PAIV) method for flow-field measurement based on a linear transducer array. The PAIV method is realized by using a Q-switched pulsed laser, a linear transducer array, a parallel data-acquisition equipment and dynamic focusing reconstruction. Tracers used to track liquid flow field were real-timely detected, two-dimensional (2-D) flow visualization was successfully reached, and flow parameters were acquired by measuring the movement of the tracer. Experimental results revealed that the PAIV method would be developed into 3-D imaging velocimetry for flow-field measurement, and potentially applied to research the security and targeting efficiency of optical nano-material probes. (c) 2010 Optical Society of America.

Improving flow patterns and spillage characteristics of a box-type commercial kitchen hood.

PubMed

Huang, Rong Fung; Chen, Jia-Kun; Han, Meng-Ji; Priyambodo, Yusuf

2014-01-01

A conventional box-type commercial kitchen hood and its improved version (termed the "IQV commercial kitchen hood") were studied using the laser-assisted smoke flow visualization technique and tracer-gas (sulfur hexafluoride) detection methods. The laser-assisted smoke flow visualization technique qualitatively revealed the flow field of the hood and the areas apt for leakages of hood containment. The tracer-gas concentration detection method measured the quantitative leakage levels of the hood containment. The oil mists that were generated in the conventional box-type commercial kitchen hood leaked significantly into the environment from the areas near the front edges of ceiling and side walls. Around these areas, the boundary-layer separation occurred, inducing highly unsteady and turbulent recirculating flow, and leading to spillages of hood containment due to inappropriate aerodynamic design at the front edges of the ceiling and side walls. The tracer-gas concentration measurements on the conventional box-type commercial kitchen hood showed that the sulfur hexafluoride concentrations detected at the hood face attained very large values on an order of magnitude about 10(3)-10(4) ppb. By combining the backward-offset narrow suction slot, deflection plates, and quarter-circular arcs at the hood entrance, the IQV commercial kitchen hood presented a flow field containing four backward-inclined cyclone flow structures. The oil mists generated by cooking were coherently confined in these upward-rising cyclone flow structures and finally exhausted through the narrow suction slot. The tracer-gas concentration measurements on the IQV commercial kitchen hood showed that the order of magnitude of the sulfur hexafluoride concentrations detected at the hood face is negligibly small--only about 10(0) ppb across the whole hood face.

Flow visualization in superfluid helium-4 using He2 molecular tracers

NASA Astrophysics Data System (ADS)

Guo, Wei

Flow visualization in superfluid helium is challenging, yet crucial for attaining a detailed understanding of quantum turbulence. Two problems have impeded progress: finding and introducing suitable tracers that are small yet visible; and unambiguous interpretation of the tracer motion. We show that metastable He2 triplet molecules are outstanding tracers compared with other particles used in helium. These molecular tracers have small size and relatively simple behavior in superfluid helium: they follow the normal fluid motion at above 1 K and will bind to quantized vortex lines below about 0.6 K. A laser-induced fluorescence technique has been developed for imaging the He2 tracers. We will present our recent experimental work on studying the normal-fluid motion by tracking thin lines of He2 tracers created via femtosecond laser-field ionization in helium. We will also discuss a newly launched experiment on visualizing vortex lines in a magnetically levitated superfluid helium drop by imaging the He2 tracers trapped on the vortex cores. This experiment will enable unprecedented insight into the behavior of a rotating superfluid drop and will untangle several key issues in quantum turbulence research. We acknowledge the support from the National Science Foundation under Grant No. DMR-1507386 and the US Department of Energy under Grant No. DE-FG02 96ER40952.

Experimental measurements of the laminar separation bubble on an Eppler 387 airfoil at low Reynolds numbers

NASA Technical Reports Server (NTRS)

Cole, Gregory M.; Mueller, Thomas J.

1990-01-01

An experimental investigation was conducted to measure the flow velocity in the boundary layer of an Eppler 387 airfoil. In particular, the laminar separation bubble that this airfoil exhibits at low Reynolds numbers was the focus. Single component laser Doppler velocimetry data were obtained at a Reynolds number of 100,000 at an angle of attack of 2.0 degree. Static Pressure and flow visualization data for the Eppler 387 airfoil were also obtained. The difficulty in obtaining accurate experimental measurements at low Reynolds numbers is addressed. Laser Doppler velocimetry boundary layer data for the NACA 663-018 airfoil at a Reynolds number of 160,000 and angle of attack of 12 degree is also presented.

OH PLIF Visualization of the UVa Supersonic Combustion Experiment: Configuration C

NASA Technical Reports Server (NTRS)

McRae, Colin D.; Johansen, Craig T.; Danehy, Paul M.; Gallo, Emanuela C. A.; Cantu, Luca M. L.; Magnotti, Gaetano; Cutler, Andrew D.; Rockwell, Robert D., Jr.; Goyne, Christopher P.; McDnaiel, James C.

2013-01-01

Non-intrusive hydroxyl radical (OH) planar laser-induced fluorescence (PLIF) measurements were obtained in configuration C of the University of Virginia supersonic combustion experiment. The combustion of hydrogen fuel injected through an unswept compression ramp into a supersonic cross-flow was imaged over a range of streamwise positions. Images were corrected for optical distortion, variations in the laser sheet profile, and different camera views. Results indicate an effect of fuel equivalence ratio on combustion zone shape and local turbulence length scale. The streamwise location of the reaction zone relative to the fuel injector was also found to be sensitive to the fuel equivalence ratio. The flow boundary conditions in the combustor section, which are sensitive to the fuel flow rate, are believed to have caused this effect. A combination of laser absorption and radiative trapping effects are proposed to have caused asymmetry observed in the images. The results complement previously published OH PLIF data obtained for configuration A along with other non-intrusive measurements to form a database for computational fluid dynamics (CFD) model validation.

Simultaneous density-field visualization and PIV of the Richtmyer-Meshkov instability

NASA Astrophysics Data System (ADS)

Prestridge, Katherine; Rightley, Paul; Benjamin, Robert; Kurnit, Norman; Boxx, Isaac; Vorobieff, Peter

1999-11-01

We describe a highly-detailed experimental characterization of the Richtmyer-Meshkov instability. A vertical curtain of heavy gas (SF_6) flows into the test section of an air-filled, horizontal shock tube, and the instability evolves after the passage of a Mach 1.2 shock past the curtain. The evolution of the curtain is visualized by seeding the SF6 with small (d ≈ 0.5 μm) glycol/water droplets using a modified theatrical fog generator. Because the event lasts only 1 ms and the initial conditions vary from test to test, rapid and high-resolution (both spatial and temporal) data acquisition is required in order to characterize the initial and dynamic conditions for each experimental event. A customized, frequency-doubled, burst mode Nd:YAG laser and a commercial single-pulse laser are used for the implementation of simultaneous density-field imaging and PIV diagnostics. We have provided data about flow scaling and mixing through image analysis, and PIV data gives us further quantitative physical insight into the evolution of the Richtmyer-Meshkov instability.

Resonant Doppler velocimeter. Ph.D. Thesis. Final Report, 1 Jul. 1974 - 31 Oct. 1979; [velocity, temperature, and pressure measurement

NASA Technical Reports Server (NTRS)

Zimmermann, M.

1980-01-01

A technique is presented for visualizing and quantitatively measuring velocity, temperature, and pressure by shining a single frequency laser beam into a gaseous flow which is seeded with an atomic species. The laser is tuned through the absorption frequencies of the seeded species and the absorption profile is detected by observing fluorescence as the atoms relax back to the ground state. The flow velocity is determined by observing the Doppler shift in the absorption frequency. Spectroscopic absorption line broadening mechanisms furnish information regarding the static temperature and pressure of the moving gas. Results of experiments conducted in the free stream and in the bow shock of a conical model mounted in a hypersonic wind tunnel indicate that the experimental uncertainties in the measurement of average values for the velocity, temperature and pressure of the flow are 0.1, 5 and 10 percent respectively.

New Hypersonic Shock Tunnel at the Laboratory of Aerothermodynamics and Hypersonics Prof. Henry T. Nagamatsu

DOE Office of Scientific and Technical Information (OSTI.GOV)

Toro, P. G. P.; Minucci, M. A. S.; Chanes, J. B. Jr

The new 0.60-m. nozzle exit diameter hypersonic shock tunnel was designed to study advanced air-breathing propulsion system such as supersonic combustion and/or laser technologies. In addition, it may be used for hypersonic flow studies and investigations of the electromagnetic (laser) energy addition for flow control. This new hypersonic shock tunnel was designed and installed at the Laboratory for of Aerothermodynamics and Hypersonics Prof. Henry T. Nagamatsu, IEAv-CTA, Brazil. The design of the tunnel enables relatively long test times, 2-10 milliseconds, suitable for the experiments performed at the laboratory. Free stream Mach numbers ranging from 6 to 25 can be producedmore » and stagnation pressures and temperatures up to 360 atm. and up to 9,000 K, respectively, can be generated. Shadowgraph and schlieren optical techniques will be used for flow visualization.« less

Implementation of and measurement with the LIPA technique in a subsonic jet

NASA Technical Reports Server (NTRS)

Falco, R. E.

1994-01-01

LIPA (Laser Induced Photochemical Anemometry) was used to measure velocity, vorticity, Reynolds stress, and turbulent intensity distributions in a subsonic jet. The jet region of interest was the area close to the jet-orifice. The LIPA-technique is a nonintrusive quantitative flow visualization technique, consisting of tracking a phosphorescing grid of fluid particles, which is impressed by laser-beams directed into the flow. The phosphorescence of biacetyl gas was used to enable tracking of the impressed light grid. In order to perform measurements in a jet, LIPA was developed and implemented for the specific flow requirements. Nitrogen was used as the carrier gas to avoid quenching of the phosphorescent radiation of the tracer gas biacetyl by ambient oxygen. The use of sulfur dioxide to sensitize phosphorescent emission of biacetyl was examined. Preliminary data was used in a discussion of the potential of the LIPA technique.

Surface Tension Driven Convection Experiment (STDCE)

NASA Technical Reports Server (NTRS)

Ostrach, Simon; Kamotani, Y.; Pline, A.

1994-01-01

Results are reported of the Surface Tension Driven Convection Experiment (STDCE) aboard the USML-1 (first United States Microgravity Laboratory) Spacelab which was launched on June 25, 1992. In the experiment 10 cSt silicone oil was placed in an open circular container which was 10 cm wide by 5 cm deep. The fluid was heated either by a cylindrical heater (1.11 cm dia.) located along the container centerline or by a CO2 laser beam to induce thermocapillary flow. The flow field was studied by flow visualization. Several thermistor probes were placed in the fluid to measure the temperature distribution. The temperature distribution along the liquid free surface was measured by an infrared imager. Tests were conducted over a range of heating powers, laser beam diameters, and free surface shapes. In conjunction with the experiments an extensive numerical modeling of the flow was conducted. In this paper some results of the velocity and temperature measurements with flat and curved free surfaces are presented and they are shown to agree well with the numerical predictions.

Wind tunnel investigation of vortex flows on F/A-18 configuration at subsonic through transonic speed

NASA Technical Reports Server (NTRS)

Erickson, Gary E.

1991-01-01

A wind tunnel experiment was conducted in the David Taylor Research Center 7- by 10-Foot Transonic Tunnel of the wing leading-edge extension (LEX) and forebody vortex flows at subsonic and transonic speeds about a 0.06-scale model of the F/A-18. The primary goal was to improve the understanding and control of the vortical flows, including the phenomena of vortex breakdown and vortex interactions with the vertical tails. Laser vapor screen flow visualizations, LEX, and forebody surface static pressures, and six-component forces and moments were obtained at angles of attack of 10 to 50 degrees, free-stream Mach numbers of 0.20 to 0.90, and Reynolds numbers based on the wing mean aerodynamic chord of 0.96 x 10(exp 6) to 1.75 x 10(exp 6). The wind tunnel results were correlated with in-flight flow visualizations and handling qualities trends obtained by NASA using an F-18 High-Alpha Research Vehicle (HARV) and by the Navy and McDonnell Douglas on F-18 aircraft with LEX fences added to improve the vertical tail buffet environment. Key issues that were addressed include the sensitivity of the vortical flows to the Reynolds number and Mach number; the reduced vertical tail excitation, and the corresponding flow mechanism, in the presence of the LEX fence; the repeatability of data obtained during high angle-of-attack wind tunnel testing of F-18 models; the effects of particle seeding for flow visualization on the quantitative model measurements; and the interpretation of off-body flow visualizations obtained using different illumination and particle seeding techniques.

Experimental scaling law for the subcritical transition to turbulence in plane Poiseuille flow.

PubMed

Lemoult, Grégoire; Aider, Jean-Luc; Wesfreid, José Eduardo

2012-02-01

We present an experimental study of the transition to turbulence in a plane Poiseuille flow. Using a well-controlled perturbation, we analyze the flow by using extensive particle image velocimetry and flow visualization (using laser-induced fluorescence) measurements, and use the deformation of the mean velocity profile as a criterion to characterize the state of the flow. From a large parametric study, four different states are defined, depending on the values of the Reynolds number and the amplitude of the perturbation. We discuss the role of coherent structures, such as hairpin vortices, in the transition. We find that the minimal amplitude of the perturbation triggering transition scales asymptotically as Re(-1).

Time-Resolved Images of Laser-Induced Gas Ignition Using High-Speed Photographic and Spectroscopic Techniques

NASA Astrophysics Data System (ADS)

Chen, Ying-Ling; Lewis, J. W. L.; Parigger, C. G.

1997-11-01

Two-dimensional visualization of laser-induced spark ignition in atmospheric-pressure gases is reported. Laser-induced breakdown in air, O2 and combustible NH_3/O2 mixture was achieved using a 1064 nm, Nd:YAG laser of approximately 6 ns pulse width, focused at 10-mm above a 60-mm diameter flat-flame burner. An argon sheath-gas flow was used to stabilize the core flowfield. High-speed photographic techniques were applied to trace a complete sequence of kernel development of a single breakdown or ignition event. Thermochemical characteristics of the post-breakdown regime were analyzed by laser-induced fluorescence spectroscopy (LIFS). Spatial distribution of NH free radical observed by planar-LIF showed the contours of the developing flame-front. The corresponding NH temperature maps achieved by excitation LIFS and Boltzmann plot are also presented.

Visualization of entry flow separation for oscillating flow in tubes

NASA Technical Reports Server (NTRS)

Qiu, Songgang; Simon, Terence W.

1992-01-01

Neutrally buoyant helium-filled soap bubbles with laser illumination are used to document entry flow separation for oscillating flow in tubes. For a symmetric entry case, the size of the separation zone appears to mildly depend on Reynolds number in the acceleration phase, but is roughly Reynolds number independent in the deceleration phase. For the asymmetric entry case, the separation zone was larger and appeared to grow somewhat during the deceleration phase. The separation zones for both entry geometry cases remain relatively small throughout the cycle. This is different from what would be observed in all-laminar, oscillator flows and is probably due to the high turbulence of the flow, particularly during the deceleration phase of the cycle.

Visualization of a Capsule Entry Vehicle Reaction-Control System (RCS) Thruster

NASA Technical Reports Server (NTRS)

Danehy, P. M.; Wilkes, J. A.; Brauckmann, G. J.; Alderfer, D. W.; Jones, S. B.; Patry, D. P.

2006-01-01

Planar laser-induced fluorescence (PLIF) was used to visualize the reaction control system (RCS) jet flow emanating from the aft-body of an Apollo-geometry capsule test article in the NASA Langley Research Center 31-Inch Mach 10 Air wind tunnel. The RCS jet was oriented normal to the aft surface of the model and had a nominal Mach number of 2.94. The composition of the jet gas by mass was 95% nitrogen (N2) and 5% nitric oxide (NO). The RCS jet flowrate varied between zero and 0.5 standard liters per minute and the angle of attack and tunnel stagnation pressure were also varied. PLIF was used to excite the NO molecules for flow visualization. These flow visualization images were processed to determine the trajectory and to quantify the flapping of the RCS jet. The spatial resolution of the jet trajectory measurement was about 1 mm and the single-shot precision of the measurement was estimated to be 0.02 mm in the far field of the jet plume. The jet flapping, measured by the standard deviation of the jet centerline position was as large as 0.9 mm, while the jet was 1.5-4 mm in diameter (full width at half maximum). Schlieren flow visualization images were obtained for comparison with the PLIF. Surface pressures were also measured and presented. Virtual Diagnostics Interface (VIDI) technology developed at NASA Langley was used to superimpose and visualize the data sets. The measurements demonstrate some of the capabilities of the PLIF method while providing a test case for computational fluid dynamics (CFD) validation.

Visualization of flow during cleaning process on a liquid nanofibrous filter

NASA Astrophysics Data System (ADS)

Bílek, P.

2017-10-01

This paper deals with visualization of flow during cleaning process on a nanofibrous filter. Cleaning of a filter is very important part of the filtration process which extends lifetime of the filter and improve filtration properties. Cleaning is carried out on flat-sheet filters, where particles are deposited on the filter surface and form a filtration cake. The cleaning process dislodges the deposited filtration cake, which is loose from the membrane surface to the retentate flow. The blocked pores in the filter are opened again and hydrodynamic properties are restored. The presented optical method enables to see flow behaviour in a thin laser sheet on the inlet side of a tested filter during the cleaning process. The local concentration of solid particles is possible to estimate and achieve new information about the cleaning process. In the article is described the cleaning process on nanofibrous membranes for waste water treatment. The hydrodynamic data were compared to the images of the cleaning process.

Turbulent boundary layer in high Rayleigh number convection in air.

PubMed

du Puits, Ronald; Li, Ling; Resagk, Christian; Thess, André; Willert, Christian

2014-03-28

Flow visualizations and particle image velocimetry measurements in the boundary layer of a Rayleigh-Bénard experiment are presented for the Rayleigh number Ra=1.4×1010. Our visualizations indicate that the appearance of the flow structures is similar to ordinary (isothermal) turbulent boundary layers. Our particle image velocimetry measurements show that vorticity with both positive and negative sign is generated and that the smallest flow structures are 1 order of magnitude smaller than the boundary layer thickness. Additional local measurements using laser Doppler velocimetry yield turbulence intensities up to I=0.4 as in turbulent atmospheric boundary layers. From our observations, we conclude that the convective boundary layer becomes turbulent locally and temporarily although its Reynolds number Re≈200 is considerably smaller than the value 420 underlying existing phenomenological theories. We think that, in turbulent Rayleigh-Bénard convection, the transition of the boundary layer towards turbulence depends on subtle details of the flow field and is therefore not universal.

Single-Camera Stereoscopy Setup to Visualize 3D Dusty Plasma Flows

NASA Astrophysics Data System (ADS)

Romero-Talamas, C. A.; Lemma, T.; Bates, E. M.; Birmingham, W. J.; Rivera, W. F.

2016-10-01

A setup to visualize and track individual particles in multi-layered dusty plasma flows is presented. The setup consists of a single camera with variable frame rate, and a pair of adjustable mirrors that project the same field of view from two different angles to the camera, allowing for three-dimensional tracking of particles. Flows are generated by inclining the plane in which the dust is levitated using a specially designed setup that allows for external motion control without compromising vacuum. Dust illumination is achieved with an optics arrangement that includes a Powell lens that creates a laser fan with adjustable thickness and with approximately constant intensity everywhere. Both the illumination and the stereoscopy setup allow for the camera to be placed at right angles with respect to the levitation plane, in preparation for magnetized dusty plasma experiments in which there will be no direct optical access to the levitation plane. Image data and analysis of unmagnetized dusty plasma flows acquired with this setup are presented.

On the combination of kinematics with flow visualization to compute total circulation - Application to vortex rings in a tube

NASA Technical Reports Server (NTRS)

Brasseur, J. G.; Chang, I.-D.

1980-01-01

To date the computation of the total circulation, or strength of a vortex has required detailed measurements of the velocity field within the vortex. In this paper a method is described in which the kinematics of the vortical flow field is exploited to calculate the strength of a vortex from relatively simple flow visualization measurements. There are several advantages in the technique, the most important being the newly acquired ability to calculate the transient changes in strength of a single vortex as it evolves. The method is applied to the study of vortex rings, although the development can be carried over directly to study vortex pairs, and it is expected that it can be generalized to other flows which contain regions of concentrated vorticity. The accuracy of the method as applied to vortex rings, assessed in part by comparing with the laser Doppler velocimeter (LDV) measurements of Sullivan et al., is shown to be excellent.

Dedicated Laboratory Setup for CO{sub 2} TEA Laser Propulsion Experiments at Rensselaer Polytechnic Institute

DOE Office of Scientific and Technical Information (OSTI.GOV)

Salvador, Israel I.; Kenoyer, David; Myrabo, Leik N.

Laser propulsion research progress has traditionally been hindered by the scarcity of photon sources with desirable characteristics, as well as integrated specialized flow facilities in a dedicated laboratory environment. For TEA CO{sub 2} lasers, the minimal requirements are time-average powers of >100 W), and pulse energies of >10 J pulses with short duration (e.g., 0.1 to 1 {mu}s); furthermore, for the advanced pulsejet engines of interest here, the laser system must simulate pulse repetition frequencies of 1-10 kilohertz or more, at least for two (carefully sequenced) pulses. A well-equipped laser propulsion laboratory should have an arsenal of sensor and diagnosticsmore » tools (such as load cells, thrust stands, moment balances, pressure and heat transfer gages), Tesla-level electromagnet and permanent magnets, flow simulation facilities, and high-speed visualization systems, in addition to other related equipment, such as optics and gas supply systems. In this paper we introduce a cutting-edge Laser Propulsion Laboratory created at Rensselaer Polytechnic Institute, one of the very few in the world to be uniquely set up for beamed energy propulsion (BEP) experiments. The present BEP research program is described, along with the envisioned research strategy that will exploit current and expanded facilities in the near future.« less

Unsteady motion of laser ablation plume by vortex induced by the expansion of curved shock wave

NASA Astrophysics Data System (ADS)

Tran, D. T.; Mori, K.

2017-02-01

There are a number of industrial applications of laser ablation in a gas atmosphere. When an intense pulsed laser beam is irradiated on a solid surface in the gas atmosphere, the surface material is ablated and expands into the atmosphere. At the same time, a spherical shock wave is launched by the ablation jet to induce the unsteady flow around the target surface. The ablated materials, luminously working as tracer, exhibit strange unsteady motions depending on the experimental conditions. By using a high-speed video camera (HPV-X2), unsteady motion ablated materials are visualized at the frame rate more than 106 fps, and qualitatively characterized.

Interaction between jet flow and motion of two consecutive membranes in a pipe

NASA Astrophysics Data System (ADS)

Boudin, Olivier; Gutmark, Ephraim

1999-11-01

Pressure oscillations induced by combustion in a rocket motor generate coherent turbulence, which excites the structure of the rocket. In particular, it leads to the vibration of inhibitors, which endangers the mechanical integrity of the rocket. To model the phenomenon, the following facility has been set up: a blower followed by a settling chamber from where the flow exits into a cylindrical pipe; at the middle a membrane is inserted with a centered hole; another membrane is installed at the end of the pipe. The main purposes are to find how the shape of the membrane hole affects the nature of the outlet flow and how two consecutive membranes interact. In addition to experimental measurements, numerical simulations of the membrane influence on the flow have been performed. Unsteady and steady CFD models have been used to analyze the influence of the hole shape. A hot wire system and a laser gave experimental data that allow us to explain phenomena observed with flow visualizations. An amplification of the amplitude of the vibrations from the first to the second membrane was observed principally through visualizations. It also appears that the vibration mode of the membranes is different from one to another for the same excitation frequency. The study of oscillation amplitude performed with the laser has showed that the membrane, which vibrates less, is the one with a circular hole. It has also detected a difference in amplitude between the long and the small edges of the rectangular hole membrane. Moreover unsteady simulations run with Fluent have described the influence of hole shape on vortex time evolution.

Flow visualization and acoustic consequences of the air moving through a static model of the human larynx.

PubMed

Kucinschi, Bogdan R; Scherer, Ronald C; DeWitt, Kenneth J; Ng, Terry T M

2006-06-01

Flow visualization with smoke particles illuminated by a laser sheet was used to obtain a qualitative description of the air flow structures through a dynamically similar 7.5x symmetric static scale model of the human larynx (divergence angle of 10 deg, minimal diameter of 0.04 cm real life). The acoustic level downstream of the vocal folds was measured by using a condenser microphone. False vocal folds (FVFs) were included. In general, the glottal flow was laminar and bistable. The glottal jet curvature increased with flow rate and decreased with the presence of the FVFs. The glottal exit flow for the lowest flow rate showed a curved jet which remained laminar for all geometries. For the higher flow rates, the jet flow patterns exiting the glottis showed a laminar jet core, transitioning to vortical structures, and leading spatially to turbulent dissipation. This structure was shortened and tightened with an increase in flow rate. The narrow FVF gap lengthened the flow structure and reduced jet curvature via acceleration of the flow. These results suggest that laryngeal flow resistance and the complex jet flow structure exiting the glottis are highly affected by flow rate and the presence of the false vocal folds. Acoustic consequences are discussed in terms of the quadrupole- and dipole-type sound sources due to ordered flow structures.

Bubble Dynamics on a Heated Surface

NASA Technical Reports Server (NTRS)

Kassemi, M.; Rashidnia, N.

1999-01-01

In this work, we study steady and oscillatory thermocapillary and natural convective flows generated by a bubble on a heated solid surface. The interaction between gas and vapor bubbles with the surrounding fluid is of interest for both space and ground-based processing. A combined numerical-experimental approach is adopted here. The temperature field is visualized using Mach-Zehnder and/or Wollaston Prism Interferometry and the flow field is observed by a laser sheet flow visualization technique. A finite element numerical model is developed which solves the transient two-dimensional continuity, momentum, and energy equations and includes the effects of temperature-dependent surface tension and bubble surface deformation. Below the critical Marangoni number, the steady state low-g and 1-g temperature and velocity fields predicted by the finite element model are in excellent agreement with both the visualization experiments in our laboratory and recently published experimental results in the literature. Above the critical Marangoni number, the model predicts an oscillatory flow which is also closely confirmed by experiments. It is shown that the dynamics of the oscillatory flow are directly controlled by the thermal and hydrodynamic interactions brought about by combined natural and thermocapillary convection. Therefore, as numerical simulations show, there are considerable differences between the 1-g and low-g temperature and flow fields at both low and high Marangoni numbers. This has serious implications for both materials processing and fluid management in space.

Particle dynamics during nanoparticle synthesis by laser ablation in a background gas

NASA Astrophysics Data System (ADS)

Nakata, Yoshiki; Muramoto, Junichi; Okada, Tatsuo; Maeda, Mitsuo

2002-02-01

Particle dynamics during Si nanoparticle synthesis in a laser-ablation plume in different background gases were investigated by laser-spectroscopic imaging techniques. Two-dimensional laser induced fluorescence and ultraviolet Rayleigh scattering techniques were used to visualize the spatial distribution of the Si atoms and nanoparticles grown, respectively. We have developed a visualization technique called re-decomposition laser-induced fluorescence to observe small nanoparticles (hereafter called clusters) which are difficult to observe by the conventional imaging techniques. In this article, the whole process of nanoparticle synthesis in different background gases of He, Ne, Ar, N2 and O2 was investigated by these techniques. In He, Ne, Ar and N2 background gases at 10 Torr, the clustering of the Si atoms started 200, 250, 300 and 800 μs after ablation, respectively. The growth rate of the clusters in He background gas was much larger than that in the other gases. The spatial distributions of the Si nanoparticles were mushroom like in He, N2 and O2, and column like in Ne and Ar. It is thought that the difference in distribution was caused by differences in the flow characteristics of the background gases, which would imply that the viscosity of the background gas is one of the main governing parameters.

Visualizing and quantifying dose distribution in a UV reactor using three-dimensional laser-induced fluorescence.

PubMed

Gandhi, Varun N; Roberts, Philip J W; Kim, Jae-Hong

2012-12-18

Evaluating the performance of typical water treatment UV reactors is challenging due to the complexity in assessing spatial and temporal variation of UV fluence, resulting from highly unsteady, turbulent nature of flow and variation in UV intensity. In this study, three-dimensional laser-induced fluorescence (3DLIF) was applied to visualize and quantitatively analyze a lab-scale UV reactor consisting of one lamp sleeve placed perpendicular to flow. Mapping the spatial and temporal fluence delivery and MS2 inactivation revealed the highest local fluence in the wake zone due to longer residence time and higher UV exposure, while the lowest local fluence occurred in a region near the walls due to short-circuiting flow and lower UV fluence rate. Comparing the tracer based decomposition between hydrodynamics and IT revealed similar coherent structures showing the dependency of fluence delivery on the reactor flow. The location of tracer injection, varying the height and upstream distance from the lamp center, was found to significantly affect the UV fluence received by the tracer. A Lagrangian-based analysis was also employed to predict the fluence along specific paths of travel, which agreed with the experiments. The 3DLIF technique developed in this study provides new insight on dose delivery that fluctuates both spatially and temporally and is expected to aid design and optimization of UV reactors as well as validate computational fluid dynamics models that are widely used to simulate UV reactor performances.

Monitoring blood-flow in the mouse cochlea using an endoscopic laser speckle contrast imaging system

PubMed Central

Yu, Sunkon; Jung, Byungjo; Choi, Jin Sil

2018-01-01

Laser speckle contrast imaging (LSCI) enables continuous high-resolution assessment of microcirculation in real-time. We applied an endoscope to LSCI to measure cochlear blood-flow in an ischemia–reperfusion mouse model. We also explored whether using xenon light in combination with LSCI facilitates visualization of anatomical position. Based on a previous preliminary study, the appropriate wavelength for penetrating the thin bony cochlea was 830 nm. A 2.7-mm-diameter endoscope was used, as appropriate for the size of the mouse cochlea. Our endoscopic LSCI system was used to illuminate the right cochlea after dissection of the mouse. We observed changes in the speckle signals when we applied the endoscopic LSCI system to the ischemia-reperfusion mouse model. The anatomical structure of the mouse cochlea and surrounding structures were clearly visible using the xenon light. The speckle signal of the cochlea was scattered, with an intensity that varied between that of the stapes (with the lowest signal), the negative control, and the stapedial artery (with the highest signal), the positive control. In the cochlear ischemia–reperfusion mouse model, the speckle signal of the cochlea decreased during the ischemic phase, and increased during the reperfusion phase, clearly reflecting cochlear blood-flow. The endoscopic LSCI system generates high-resolution images in real-time, allowing visualization of blood-flow and its changes in the mouse cochlea. Anatomical structures were clearly matched using LSCI along with visible light. PMID:29489849

Monitoring blood-flow in the mouse cochlea using an endoscopic laser speckle contrast imaging system.

PubMed

Kong, Tae Hoon; Yu, Sunkon; Jung, Byungjo; Choi, Jin Sil; Seo, Young Joon

2018-01-01

Laser speckle contrast imaging (LSCI) enables continuous high-resolution assessment of microcirculation in real-time. We applied an endoscope to LSCI to measure cochlear blood-flow in an ischemia-reperfusion mouse model. We also explored whether using xenon light in combination with LSCI facilitates visualization of anatomical position. Based on a previous preliminary study, the appropriate wavelength for penetrating the thin bony cochlea was 830 nm. A 2.7-mm-diameter endoscope was used, as appropriate for the size of the mouse cochlea. Our endoscopic LSCI system was used to illuminate the right cochlea after dissection of the mouse. We observed changes in the speckle signals when we applied the endoscopic LSCI system to the ischemia-reperfusion mouse model. The anatomical structure of the mouse cochlea and surrounding structures were clearly visible using the xenon light. The speckle signal of the cochlea was scattered, with an intensity that varied between that of the stapes (with the lowest signal), the negative control, and the stapedial artery (with the highest signal), the positive control. In the cochlear ischemia-reperfusion mouse model, the speckle signal of the cochlea decreased during the ischemic phase, and increased during the reperfusion phase, clearly reflecting cochlear blood-flow. The endoscopic LSCI system generates high-resolution images in real-time, allowing visualization of blood-flow and its changes in the mouse cochlea. Anatomical structures were clearly matched using LSCI along with visible light.

Investigation of hydrodynamic characteristics of laminar flow condition around sphere using PIV system

NASA Astrophysics Data System (ADS)

Abed, A. H.; Shcheklein, S. E.

2018-05-01

This paper aims to determine the hydrodynamic characteristics of flow around the sphere in unsteady state condition. An experimental test-rig was designed and constructed for this purpose with the application of an adjusted laser optics system. It is based on the technology of pulsed particle visualization of micro tracers in the cross section per unit time interval. Visualization with Particle Image Velocimetry (PIV-system) is used to study the properties of the flow such as its structure. The PIV-system is the most accepted technique allowed one to measure the instantaneous velocity distribution in fluid applications. In this experimental study, o-ring is used to simulate turbulence on the sphere surface and creates very high-level fluctuations, which creates the flow undergoing a laminar-to-turbulent transition. This transition leads to a delay of the separation point of flow from the sphere surface causing a significant reduction in the drag coefficient, reaching 45%. New results obtained can be useful in the development of numerical validation as well as in design processes.

Femtosecond Laser Tagging Characterization of a Sweeping Jet Actuator Operating in the Compressible Regime

NASA Technical Reports Server (NTRS)

Peters, Christopher J.; Miles, Richard B.; Burns, Ross A.; Bathel, Brett F.; Jones, Gregory S.; Danehy, Paul M.

2016-01-01

A sweeping jet (SWJ) actuator operating over a range of nozzle pressure ratios (NPRs) was characterized with femtosecond laser electronic excitation tagging (FLEET), single hot-wire anemometry (HWA) and high-speed/phase-averaged schlieren. FLEET velocimetry was successfully demonstrated in a highly unsteady, oscillatory flow containing subsonic through supersonic velocities. Qualitative comparisons between FLEET and HWA (which measured mass flux since the flow was compressible) showed relatively good agreement in the external flow profiles. The spreading rate was found to vary from 0.5 to 1.2 depending on the pressure ratio. The precision of FLEET velocity measurements in the external flow field was poorer (is approximately equal to 25 m/s) than reported in a previous study due to the use of relatively low laser fluences, impacting the velocity fluctuation measurements. FLEET enabled velocity measurements inside the device and showed that choking likely occurred for NPR = 2.0, and no internal shockwaves were present. Qualitative oxygen concentration measurements using FLEET were explored in an effort to gauge the jet's mixing with the ambient. The jet was shown to mix well within roughly four throat diameters and mix fully within roughly eight throat diameters. Schlieren provided visualization of the internal and external flow fields and showed that the qualitative structure of the internal flow does not vary with pressure ratio and the sweeping mechanism observed for incompressible NPRs also probably holds for compressible NPRs.

Investigation of Mixing a Supersonic Stream with the Flow Downstream of a Wedge

NASA Technical Reports Server (NTRS)

Sheeley, Joseph

1997-01-01

The flow characteristics in the base region of a two-dimensional supersonic compression ramp are investigated. A stream-wise oriented air jet, M = 1.75, is injected through a thin horizontal slot into a supersonic air main flow, M = 2.3, at the end of a two-dimensional compression ramp. The velocity profile and basic characteristics of the flow in the base region immediately following the ramp are determined. Visualization of the flowfield for qualitative observations is accomplished via Dark Central Ground Interferometry (DCGI). Two-dimensional velocity profiles are obtained using Laser Doppler Velocimetry (LDV). The study is the initial phase of a four-year investigation of base flow mixing. The current study is to provide more details of the flowfield.

21 CFR 886.1360 - Visual field laser instrument.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Visual field laser instrument. 886.1360 Section... (CONTINUED) MEDICAL DEVICES OPHTHALMIC DEVICES Diagnostic Devices § 886.1360 Visual field laser instrument. (a) Identification. A visual field laser instrument is an AC-powered device intended to provide...

21 CFR 886.1360 - Visual field laser instrument.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Visual field laser instrument. 886.1360 Section... (CONTINUED) MEDICAL DEVICES OPHTHALMIC DEVICES Diagnostic Devices § 886.1360 Visual field laser instrument. (a) Identification. A visual field laser instrument is an AC-powered device intended to provide...

21 CFR 886.1360 - Visual field laser instrument.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Visual field laser instrument. 886.1360 Section... (CONTINUED) MEDICAL DEVICES OPHTHALMIC DEVICES Diagnostic Devices § 886.1360 Visual field laser instrument. (a) Identification. A visual field laser instrument is an AC-powered device intended to provide...

21 CFR 886.1360 - Visual field laser instrument.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Visual field laser instrument. 886.1360 Section... (CONTINUED) MEDICAL DEVICES OPHTHALMIC DEVICES Diagnostic Devices § 886.1360 Visual field laser instrument. (a) Identification. A visual field laser instrument is an AC-powered device intended to provide...

Randomized controlled trial of electro-stimulation therapies to modulate retinal blood flow and visual function in retinitis pigmentosa.

PubMed

Bittner, Ava K; Seger, Kenneth; Salveson, Rachel; Kayser, Samantha; Morrison, Natalia; Vargas, Patricia; Mendelsohn, Deborah; Han, Jorge; Bi, Hua; Dagnelie, Gislin; Benavente, Alexandra; Ramella-Roman, Jessica

2018-05-01

We examined changes in visual function and ocular and retinal blood flow (RBF) among retinitis pigmentosa (RP) participants in a randomized controlled trial of electro-stimulation therapies. Twenty-one RP participants were randomized (1:1:1) to transcorneal electrical stimulation (TES) at 6 weekly half-hour sessions, electro-acupuncture or inactive laser acupuncture (sham control) at 10 half-hour sessions over 2 weeks. Early Treatment of Diabetic Retinopathy Study (ETDRS) visual acuity (VA), quick contrast sensitivity function, Goldmann visual fields, AdaptDx scotopic sensitivity, spectral flow and colour Doppler imaging of the central retinal artery (CRA), and RBF in macular capillaries were measured twice pre-treatment, after 2 TES sessions, within a week and a month after intervention completion. We measured a significant improvement in retrobulbar CRA mean flow velocity for both the TES (p = 0.038) and electro-acupuncture groups (p = 0.001) on average after 2 weeks of treatment when compared to sham controls. Transcorneal electrical simulation (TES) and electro-acupuncture subjects had significant 55% and 34% greater increases, respectively, in RBF in the macular vessels when compared to sham controls (p < 0.001; p = 0.008) within a week of completing six TES sessions or a month after electro-acupuncture. There was a significant difference in the proportion of eyes that had improved visual function when comparing the three intervention groups (p = 0.038): four of seven TES subjects (57%), two of seven electro-acupuncture subjects (29%) and none of the seven control subjects (0%) had a significant visual improvement outside of typical test-retest variability at two consecutive post-treatment visits. Increased blood flow following electro-stimulation therapies is an objective, physiological change that occurred in addition to visual function improvements in some RP patients. © 2017 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

Identification of Instability Modes of Transition in Underexpanded Jets

NASA Technical Reports Server (NTRS)

Inman, Jennifer A.; Danehy, Paul M.; Nowak, Robert J.; Alderfer, David W.

2008-01-01

A series of experiments into the behavior of underexpanded jet flows has been conducted at NASA Langley Research Center. Two nozzles supplied with high-pressure gas were used to generate axisymmetric underexpanded jets exhausting into a low-pressure chamber. These nozzles had exit Mach numbers of 1 and 2.6, though this paper will present cases involving only the supersonic nozzle. Reynolds numbers based on nozzle exit conditions ranged from about 300 to 22,000, and nozzle exit-to-ambient jet pressure ratios ranged from about 1 to 25. For the majority of cases, the jet fluid was a mixture of 99.5% nitrogen seeded with 0.5% nitric oxide (NO). Planar laser-induced fluorescence (PLIF) of NO is used to visualize the flow, visualizing planar slices of the flow rather than path integrated measurements. In addition to revealing the size and location of flow structures, PLIF images were also used to identify unsteady jet behavior in order to quantify the conditions governing the transition to turbulent flow. Flow structures that contribute to the growth of flow instabilities have been identified, and relationships between Reynolds number and transition location are presented. By highlighting deviations from mean flow properties, PLIF images are shown to aide in the identification and characterization of flow instabilities and the resulting process of transition to turbulence.

Fluorescence Visualization of Hypersonic Flow Past Triangular and Rectangular Boundary-layer Trips

NASA Technical Reports Server (NTRS)

Danehy, Paul M.; Garcia, A. P.; Borg, Stephen E.; Dyakonov, Artem A.; Berry, Scott A.; Inman, Jennifer A.; Alderfer, David W.

2007-01-01

Planar laser-induced fluorescence (PLIF) flow visualization has been used to investigate the hypersonic flow of air over surface protrusions that are sized to force laminar-to-turbulent boundary layer transition. These trips were selected to simulate protruding Space Shuttle Orbiter heat shield gap-filler material. Experiments were performed in the NASA Langley Research Center 31-Inch Mach 10 Air Wind Tunnel, which is an electrically-heated, blowdown facility. Two-mm high by 8-mm wide triangular and rectangular trips were attached to a flat plate and were oriented at an angle of 45 degrees with respect to the oncoming flow. Upstream of these trips, nitric oxide (NO) was seeded into the boundary layer. PLIF visualization of this NO allowed observation of both laminar and turbulent boundary layer flow downstream of the trips for varying flow conditions as the flat plate angle of attack was varied. By varying the angle of attack, the Mach number above the boundary layer was varied between 4.2 and 9.8, according to analytical oblique-shock calculations. Computational Fluid Dynamics (CFD) simulations of the flowfield with a laminar boundary layer were also performed to better understand the flow environment. The PLIF images of the tripped boundary layer flow were compared to a case with no trip for which the flow remained laminar over the entire angle-of-attack range studied. Qualitative agreement is found between the present observed transition measurements and a previous experimental roughness-induced transition database determined by other means, which is used by the shuttle return-to-flight program.

Pratt & Whitney Advanced Ducted Propulsor (ADP) Engine Test in 40x80ft w.t.: Engineers Peter

NASA Technical Reports Server (NTRS)

1993-01-01

Pratt & Whitney Advanced Ducted Propulsor (ADP) Engine Test in 40x80ft w.t.: Engineers Peter Zell (left) and Dr Clifton Horne (right) are shown preparing a laser light sheet for a flow visualization test. Shown standing in the nacelle of the ADP is John Girvin, senior test engineer for Pratt & Whitney.

Pratt & Whitney Advanced Ducted Propulsor (ADP) Engine Test in 40x80ft w.t.: Engineers Peter

NASA Technical Reports Server (NTRS)

1993-01-01

Pratt & Whitney Advanced Ducted Propulsor (ADP) Engine Test in 40x80ft w.t.: Engineers Peter Zell (left) and Dr Clifton Horne (right) are shown preparing for a laser light sheet for a flow visualization test. Shown standing in the nacelle of the ADP is John Girvin, senior test engineer for Pratt & Whitney.

Laser-Based Flowfield Imaging in a Lean Premixed Prevaporized Sector Combustor

NASA Technical Reports Server (NTRS)

Hicks, Yolanda R.; Locke, Randy J.; Anderson, Robert C.

2005-01-01

OH and fuel planar laser-induced fluorescence (PLIF) is used qualitatively in this study to observe the flame structure resultant from different fuel injector dome configurations within the 3-cup sector combustor test rig. The fluorescence images are compared with some computational fluid dynamics (CFD) results. Interferences in obtaining OH fluorescence signals due to the emission of other species are assessed. NO PLIF images are presented and compared to gas analysis results. The comparison shows that PLIF NO can be an excellent method for measuring NO in the flame. Additionally, we present flow visualization of the molecular species C2.

NASA programs in advanced sensors and measurement technology for aeronautical applications

NASA Astrophysics Data System (ADS)

Conway, Bruce A.

NASA involvement in the development, implementation, and experimental use of advanced aeronautical sensors and measurement technologies is presently discussed within the framework of specific NASA research centers' activities. The technology thrusts are in the fields of high temperature strain gages and microphones, laser light-sheet flow visualization, LTA, LDV, and LDA, tunable laser-based aviation meteorology, and fiber-optic CARS measurements. IR thermography and close-range photogrammetry are undergoing substantial updating and application. It is expected that 'smart' sensors will be increasingly widely used, especially in conjunction with smart structures in aircraft and spacecraft.

Measurement of fluid properties using rapid-double-exposure and time-average holographic interferometry

NASA Technical Reports Server (NTRS)

Decker, A. J.

1984-01-01

The holographic recording of the time history of a flow feature in three dimensions is discussed. The use of diffuse illumination holographic interferometry or the three dimensional visualization of flow features such as shock waves and turbulent eddies is described. The double-exposure and time-average methods are compared using the characteristic function and the results from a flow simulator. A time history requires a large hologram recording rate. Results of holographic cinematography of the shock waves in a flutter cascade are presented as an example. Future directions of this effort, including the availability and development of suitable lasers, are discussed.

The dorsal raphe modulates sensory responsiveness during arousal in zebrafish

PubMed Central

Yokogawa, Tohei; Hannan, Markus C.; Burgess, Harold A.

2012-01-01

During waking behavior animals adapt their state of arousal in response to environmental pressures. Sensory processing is regulated in aroused states and several lines of evidence imply that this is mediated at least partly by the serotonergic system. However there is little information directly showing that serotonergic function is required for state-dependent modulation of sensory processing. Here we find that zebrafish larvae can maintain a short-term state of arousal during which neurons in the dorsal raphe modulate sensory responsiveness to behaviorally relevant visual cues. Following a brief exposure to water flow, larvae show elevated activity and heightened sensitivity to perceived motion. Calcium imaging of neuronal activity after flow revealed increased activity in serotonergic neurons of the dorsal raphe. Genetic ablation of these neurons abolished the increase in visual sensitivity during arousal without affecting baseline visual function or locomotor activity. We traced projections from the dorsal raphe to a major visual area, the optic tectum. Laser ablation of the tectum demonstrated that this structure, like the dorsal raphe, is required for improved visual sensitivity during arousal. These findings reveal that serotonergic neurons of the dorsal raphe have a state-dependent role in matching sensory responsiveness to behavioral context. PMID:23100441

Feasibility of Rayleigh Scattering Flow Diagnostics in the National Transonic Facility

NASA Technical Reports Server (NTRS)

Herring, Gregory C.; Lee, Joseph W.; Goad, William K.

2015-01-01

Laser-based Rayleigh light scattering (RLS) was performed in the National Transonic Facility (NTF) at NASA Langley Research Center. The goal was to determine if the free-stream flow undergoes clustering (early stage of condensation from gas to liquid) or remains in a pure diatomic molecular phase. Data indicate that clusters are not observable down to levels of 10% of the total light scatter for a variety of total pressures at one N2 cryogenic-mode total temperature (Tt = -50 F = 227 K) and one air-mode temperature (Tt = +130 F = 327 K). Thus RLS appears viable as a qualitative or quantitative diagnostic for flow density in NTF in the future. Particles are distinguished from optically unresolvable clusters because they are much larger and individually resolvable in the laser beam image with Mie scattering. The same RLS apparatus was also used, without modification, to visualize naturally occurring particles entrained in the flow for both cryogenic and air-modes. Estimates of the free-stream particle flux are presented, which may be important for interpretation of laminar-to-turbulent boundary-layer transition studies. 1

Experimental Analyses of Flow Field Structures around Clustered Linear Aerospike Nozzles

NASA Astrophysics Data System (ADS)

Taniguchi, Mashio; Mori, Hideo; Nishihira, Ryutaro; Niimi, Tomohide

2005-05-01

An aerospike nozzle has been expected as a candidate for an engine of a reusable space shuttle to respond to growing demand for rocket-launching and its cost reduction. In this study, the flow field structures in any cross sections around clustered linear aerospike nozzles are visualized and analyzed, using laser induced fluorescence (LIF) of NO seeded in the carrier gas N2. Since flow field structures are affected mainly by pressure ratio (Ps/Pa, Ps: the source pressure in a reservoir, Pa: the ambient pressure in the vacuum chamber), the clustered linear aerospike nozzle is set inside a vacuum chamber to carry out the experiments in the wide range of pressure ratios from 75 to 200. Flow fields are visualized in several cross-sections, demonstrating the complicated three-dimensional flow field structures. Pressure sensitive paint (PSP) of PtTFPP bound by poly-IBM-co-TFEM is also applied to measurement of the complicated pressure distribution on the spike surface, and to verification of contribution of a truncation plane to the thrust. Finally, to examine the effect of the sidewalls attached to the aerospike nozzle, the flow fields around the nozzle with the sidewalls are compared with those without sidewalls.

A Scanning laser-velocimeter technique for measuring two-dimensional wake-vortex velocity distributions. [Langley Vortex Research Facility

NASA Technical Reports Server (NTRS)

Gartrell, L. R.; Rhodes, D. B.

1980-01-01

A rapid scanning two dimensional laser velocimeter (LV) has been used to measure simultaneously the vortex vertical and axial velocity distributions in the Langley Vortex Research Facility. This system utilized a two dimensional Bragg cell for removing flow direction ambiguity by translating the optical frequency for each velocity component, which was separated by band-pass filters. A rotational scan mechanism provided an incremental rapid scan to compensate for the large displacement of the vortex with time. The data were processed with a digital counter and an on-line minicomputer. Vaporized kerosene (0.5 micron to 5 micron particle sizes) was used for flow visualization and LV scattering centers. The overall measured mean-velocity uncertainity is less than 2 percent. These measurements were obtained from ensemble averaging of individual realizations.

Low-Amplitude Topographic Features and Textures on the Moon: Initial Results from Detrended Lunar Orbiter Laser Altimeter (LOLA) Topography

NASA Technical Reports Server (NTRS)

Kreslavsky, Mikhail A.; Head, James W.; Neumann, Gregory A.; Zuber, Maria T.; Smith, David E.

2016-01-01

Global lunar topographic data derived from ranging measurements by the Lunar Orbiter Laser Altimeter (LOLA) onboard LRO mission to the Moon have extremely high vertical precision. We use detrended topography as a means for utilization of this precision in geomorphological analysis. The detrended topography was calculated as a difference between actual topography and a trend surface defined as a median topography in a circular sliding window. We found that despite complicated distortions caused by the non-linear nature of the detrending procedure, visual inspection of these data facilitates identification of low-amplitude gently-sloping geomorphic features. We present specific examples of patterns of lava flows forming the lunar maria and revealing compound flow fields, a new class of lava flow complex on the Moon. We also highlight the identification of linear tectonic features that otherwise are obscured in the images and topographic data processed in a more traditional manner.

Self-sustained flow oscillations and heat transfer in radial flow through co-rotating parallel disks

NASA Astrophysics Data System (ADS)

Mochizuki, S.; Inoue, T.

1990-03-01

An experimental study was conducted to determine the fluid flow and heat transfer characteristics in a passage formed by two parallel rotating disks. The local heat transfer coefficients along the disk radius were measured in detail and the flow patterns between the two rotating disks were visualized by using paraffin mist and a laser-light sheet. It was disclosed that: (1) the self-sustained laminar flow separation which is characteristic of the stationary disks still exists even when the disks are set in motion, giving significant influence to the heat transfer; (2) for small source flow Reynolds number, Re, and large rotational Reynolds number, Re(omega), rotating stall dominates the heat transfer; and (3) heat transfer for steady laminar flow occurs only when Re is less than 1200 and Re(omega) is less than 20.

Dual-pulse laser ignition of ethylene-air mixtures in a supersonic combustor.

PubMed

Yang, Leichao; An, Bin; Liang, Jianhan; Li, Xipeng; Wang, Zhenguo

2018-04-02

To reduce the energy of an individual laser pulse, dual-pulse laser ignitions (LIs) at various pulse intervals were investigated in a Mach 2.92 scramjet engine fueled with ethylene. For comparison, experiments on a single-pulse LI were also performed. Schlieren visualization and high-speed photography were employed to observe the ignition processes simultaneously. The results indicate that the energy of an individual laser pulse can be reduced by half via a dual-pulse LI method as compared with a single-pulse LI with the same total energy. The reduction of the individual laser pulse energy degrades the requirements on the laser source and the beam delivery system, which facilitates the practical application of LI in hypersonic vehicles. A pulse interval shorter than 40 μs is suggested for dual-pulse LI in the present study. Because of the intense heat loss and radical dissipation in high-speed flows, the pulse interval for dual-pulse LI should be short enough to narrow the spatial distribution of the initial flame kernel.

PLIF Imaging of Capsule RCS Jets, Shear Layers, and Simulated Forebody Ablation

NASA Technical Reports Server (NTRS)

Inman, Jennifer A.; Danehy, Paul M.; Alderfer, David W.; Buck, Gregory M.; McCrea, Andrew

2008-01-01

Planar laser-induced fluorescence (PLIF) has been used to investigate hypersonic flows associated with capsule reentry vehicles. These flows included reaction control system (RCS) jets, shear layer flow, and simulated forebody heatshield ablation. Pitch, roll, and yaw RCS jets were studied. PLIF obtained planar slices in these flowfields. These slices could be viewed individually or they could be combined using computer visualization techniques to reconstruct the three dimensional shape of the flow. The tests described herein were conducted in the 31-Inch Mach 10 Air Tunnel at NASA Langley Research Center. Improvements to many facets of the imaging system increased the efficiency and quality of both data acquisition, in addition to increasing the overall robustness of the system.

Combination of Kinematics with Flow Visualization to Compute Total Circulation

NASA Technical Reports Server (NTRS)

Brasseur, J. G; Chang, I-Dee

1981-01-01

A method is described in which kinematics is exploited to compute the total circulation of a vortex from relatively simple flow visualization experiments. There are several advantages in the technique, including the newly acquired ability to calculate the changes in strength of a single vortex as it evolves. The main concepts and methodology are discussed in a general way for application to vortices which carry along with them definable regions of essentially irrotational fluid; however, the approach might be generalized to other flows which contain regions of concentrated vorticity. As an illustrative example, an application to the study of the transient changes in total circulation of individual vortex rings as they travel up a tube is described, taking into account the effect of the tube boundary. The accuracy of the method, assessed in part by a direct comparison with a laser Doppler measurement is felt to be well within experimental precision for vortex rings over a wide range of Reynolds numbers.

Visualization of chorioretinal vasculature in mice in vivo using a combined OCT/SLO imaging system

NASA Astrophysics Data System (ADS)

Goswami, Mayank; Zhang, Pengfei; Pugh, Edward N.; Zawadzki, Robert J.

2016-03-01

Chorioretinal blood vessel morphology in mice is of great interest to researchers studying eye disease mechanisms in animal models. Two leading retinal imaging modalities -- Optical Coherence Tomography (OCT) and Scanning Laser Ophthalmoscopy (SLO) -- have offered much insight into vascular morphology and blood flow. OCT "flow-contrast" methods have provided detailed mapping of vascular morphology with micrometer depth resolution, while OCT Doppler methods have enabled the measurement of local flow velocities. SLO remains indispensable in studying blood leakage, microaneurysms, and the clearance time of contrast agents of different sizes. In this manuscript we present results obtained with a custom OCT/SLO system applied to visualize the chorioretinal vascular morphology of pigmented C57Bl/6J and albino nude (Nu/Nu) mice. Blood perfusion maps of choroidal vessels and choricapillaris created by OCT and SLO are presented, along with detailed evaluation of different OCT imaging parameters, including the use of the scattering contrast agent Intralipid. Future applications are discussed.

Modeling laser speckle imaging of perfusion in the skin (Conference Presentation)

NASA Astrophysics Data System (ADS)

Regan, Caitlin; Hayakawa, Carole K.; Choi, Bernard

2016-02-01

Laser speckle imaging (LSI) enables visualization of relative blood flow and perfusion in the skin. It is frequently applied to monitor treatment of vascular malformations such as port wine stain birthmarks, and measure changes in perfusion due to peripheral vascular disease. We developed a computational Monte Carlo simulation of laser speckle contrast imaging to quantify how tissue optical properties, blood vessel depths and speeds, and tissue perfusion affect speckle contrast values originating from coherent excitation. The simulated tissue geometry consisted of multiple layers to simulate the skin, or incorporated an inclusion such as a vessel or tumor at different depths. Our simulation used a 30x30mm uniform flat light source to optically excite the region of interest in our sample to better mimic wide-field imaging. We used our model to simulate how dynamically scattered photons from a buried blood vessel affect speckle contrast at different lateral distances (0-1mm) away from the vessel, and how these speckle contrast changes vary with depth (0-1mm) and flow speed (0-10mm/s). We applied the model to simulate perfusion in the skin, and observed how different optical properties, such as epidermal melanin concentration (1%-50%) affected speckle contrast. We simulated perfusion during a systolic forearm occlusion and found that contrast decreased by 35% (exposure time = 10ms). Monte Carlo simulations of laser speckle contrast give us a tool to quantify what regions of the skin are probed with laser speckle imaging, and measure how the tissue optical properties and blood flow affect the resulting images.

Easy performance of 6-color confocal immunofluorescence with 4-laser line microscopes.

PubMed

Eissing, Nathalie; Heger, Lukas; Baranska, Anna; Cesnjevar, Robert; Büttner-Herold, Maike; Söder, Stephan; Hartmann, Arndt; Heidkamp, Gordon F; Dudziak, Diana

2014-09-01

Confocal laser scanning microscopy is an advanced technique for imaging tissue samples in vitro and in vivo at high optical resolution. The development of new fluorochrome variants do not only make it possible to perform multicolor flow cytometry of single cells, but in combination with high resolution laser scanning systems also to investigate the distribution of cells in lymphoid tissues by confocal immunofluorescence analyses, thus allowing the distinction of various cell populations directly in the tissue. Here, we provide a protocol for the visualization of at least six differently fluorochrome-labeled antibodies at the same time using a conventional confocal laser scanning microscope with four laser lines (405 nm, 488 nm, 555 nm, and 639 nm laser wavelength) in both murine and human tissue samples. We further demonstrate that compensation correction algorithms are not necessary to reduce spillover of fluorochromes into other channels when the used fluorochromes are combined according to their specific emission bands and the varying Stokes shift for co-excited fluorochromes with the same laser line. Copyright © 2014 Elsevier B.V. All rights reserved.

Time-resolved microscopy of fs-laser-induced heat flows in glasses

NASA Astrophysics Data System (ADS)

Bonse, Jörn; Seuthe, Thomas; Grehn, Moritz; Eberstein, Markus; Rosenfeld, Arkadi; Mermillod-Blondin, Alexandre

2018-01-01

Time-resolved phase-contrast microscopy is employed to visualize spatio-temporal thermal transients induced by tight focusing of a single Ti:sapphire fs-laser pulse into a solid dielectric sample. This method relies on the coupling of the refractive index change and the sample temperature through the thermo-optic coefficient d n/d T. The thermal transients are studied on a timescale ranging from 10 ns up to 0.1 ms after laser excitation. Beyond providing direct insights into the laser-matter interaction, analyzing the results obtained also enables quantifying the local thermal diffusivity of the sample on a micrometer scale. Studies conducted in different solid dielectrics, namely amorphous fused silica (a-SiO2), a commercial borosilicate glass (BO33, Schott), and a custom alkaline earth silicate glass (NaSi66), illustrate the applicability of this approach to the investigation of various glassy materials.

Investigation of light source and scattering medium related to vapor-screen flow visualization in a supersonic wind tunnel

NASA Technical Reports Server (NTRS)

Snow, W. L.; Morris, O. A.

1984-01-01

Methods for increasing the radiant in light sheets used for vapor screen set-ups were investigated. Both high-pressure mercury arc lamps and lasers were considered. Pulsed operation of the air-cooled 1-kW lamps increased the light output but decreased reliability. An ellipsoidal mirror improved the output of the air-cooled lamps by concentrating the light but increased the complexity of the housing. Water-cooled-4-kW lamps coupled with high-aperture Fresnel lenses provided reasonable improvements over the air-cooled lamps. Fanned laser beams measurements of scattered light versus dew point made in conjunction with successful attempts to control the fluid injection. A number of smoke generators are described and test results comparing smoke and vapor screens are shown. Finally, one test included a periscope system to relay the image to a camera outside the flow.

Flow measurements in a water tunnel using a holocinematographic velocimeter

NASA Technical Reports Server (NTRS)

Weinstein, Leonard M.; Beeler, George B.

1987-01-01

Dual-view holographic movies were used to examine complex flows with full three-space and time resolution. This approach, which tracks the movement of small tracer particles in water, is termed holocinematographic velocimetry (HCV). A small prototype of a new water tunnel was used to demonstrate proof-of-concept for the HCV. After utilizing a conventional flow visualization apparatus with a laser light sheet to illuminate tracer particles to evaluate flow quality of the prototype tunnel, a simplified version of the HCV was employed to demonstrate the capabilities of the approach. Results indicate that a full-scale version of the water tunnel and a high performance version of the HCV should be able to check theoretical and numerical modeling of complex flows and examine the mechanisms operative in turbulent and vortex flow control concepts, providing an entirely unique instrument capable, for the first time, of simultaneous three-space and time measurements in turbulent flow.

Velocity visualization in gaseous flows

NASA Technical Reports Server (NTRS)

Hanson, R. K.; Hiller, B.; Hassa, C.; Booman, R. A.

1984-01-01

Techniques yielding simultaneous, multiple-point measurements of velocity in reacting or nonreacting flow fields have the potential to significantly impact basic and applied studies of fluid mechanics. This research program is aimed at investigating several candidate schemes which could provide such measurement capability. The concepts under study have in common the use of a laser source (to illuminate a column, a grid, a plane or a volume in the flow) and the collection of light at right angles (from Mie scattering, fluorescence, phosphorescence or chemiluminescence) using a multi-element solid-state camera (100 x 100 array of photodiodes). The work will include an overview and a status report of work in progress with particular emphasis on the method of Doppler-modulated absorption.

Some comments on particle image displacement velocimetry

NASA Technical Reports Server (NTRS)

Lourenco, L. M.

1988-01-01

Laser speckle velocimetry (LSV) or particle image displacement velocimetry, is introduced. This technique provides the simultaneous visualization of the two-dimensional streamline pattern in unsteady flows as well as the quantification of the velocity field over an entire plane. The advantage of this technique is that the velocity field can be measured over an entire plane of the flow field simultaneously, with accuracy and spatial resolution. From this the instantaneous vorticity field can be easily obtained. This constitutes a great asset for the study of a variety of flows that evolve stochastically in both space and time. The basic concept of LSV; methods of data acquisition and reduction, examples of its use, and parameters that affect its utilization are described.

Measurement of fluid properties using rapid-double-exposure and time-average holographic interferometry

NASA Technical Reports Server (NTRS)

Decker, A. J.

1984-01-01

The holographic recording of the time history of a flow feature in three dimensions is discussed. The use of diffuse illumination holographic interferometry or the three-dimensional visualization of flow features such as shock waves and turbulent eddies is described. The double-exposure and time-average methods are compared using the characteristic function and the results from a flow simulator. A time history requires a large hologram recording rate. Results of holographic cinematography of the shock waves in a flutter cascade are presented as an example. Future directions of this effort, including the availability and development of suitable lasers, are discussed. Previously announced in STAR as N84-21849

High-Temperature Optical Window Design

NASA Technical Reports Server (NTRS)

Roeloffs, Norman; Taranto, Nick

1995-01-01

A high-temperature optical window is essential to the optical diagnostics of high-temperature combustion rigs. Laser Doppler velocimetry, schlieren photography, light sheet visualization, and laser-induced fluorescence spectroscopy are a few of the tests that require optically clear access to the combustor flow stream. A design was developed for a high-temperature window that could withstand the severe environment of the NASA Lewis 3200 F Lean Premixed Prevaporized (LPP) Flame Tube Test Rig. The development of this design was both time consuming and costly. This report documents the design process and the lessons learned, in an effort to reduce the cost of developing future designs for high-temperature optical windows.

The development of laser speckle velocimetry for the measurement of vortical flow fields

NASA Technical Reports Server (NTRS)

Smith, C. A.; Lourenco, L. M. M.; Krothapalli, A.

1986-01-01

A new velocity measurement technique is described that provides the simultaneous visualization of a two-dimensional streamline pattern and the quantification of the velocity field. The main advantage of this technique is that the velocity field can be measured with sufficient accuracy and spatial resolution so that the vorticity field can be readily obtained. This technique is ideally suited for the study of unsteady vortical flows, which occur in rotorcraft and in high-angle-of-attack aerodynamics. The technique, some of the important parameters that affect its use, and some recent examples are described.

Experimental and numerical studies on three dimensional GTA weld pool convection: Non-axisymmetric effects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Joshi, Y.; Dutta, P.; Schupp, P.E.

1995-12-31

Observations of surface flow patterns of steel and aluminum GTAW pools have been made using a pulsed laser visualization system. The weld pool convection is found to be three dimensional, with the azimuthal circulation depending on the location of the clamp with respect to the torch. Oscillation of steel pools and undulating motion in aluminum weld pools are also observed even with steady process parameters. Current axisymmetric numerical models are unable to explain such phenomena. A three dimensional computational study is carried out in this study to explain the rotational flow in aluminum weld pools.

Some observations of separated flow on finite wings

NASA Technical Reports Server (NTRS)

Winkelmann, A. E.; Ngo, H. T.; De Seife, R. C.

1982-01-01

Wind tunnel test results for aspects of flow over airfoils exhibiting single and multiple trailing edge stall 'mushroom' cells are reported. Rectangular wings with aspect ratios of 4.0 and 9.0 were tested at Reynolds numbers of 480,000 and 257,000, respectively. Surface flow patterns were visualized by means of a fluorescent oil flow technique, separated flow was observed with a tuft wand and a water probe, spanwise flow was studied with hot-wire anemometry, smoke flow and an Ar laser illuminated the centerplane flow, and photographs were made of the oil flow patterns. Swirl patterns on partially and fully stalled wings suggested vortex flow attachments in those regions, and a saddle point on the fully stalled AR=4.0 wing indicated a secondary vortex flow at the forward region of the separation bubble. The separation wake decayed downstream, while the tip vortex interacted with the separation bubble on the fully stalled wing. Three mushroom cells were observed on the AR=9.0 wing.

Jet Evolution Visualized and Quantified Using Filtered Rayleigh Scattering

NASA Technical Reports Server (NTRS)

Reeder, Mark F.

1996-01-01

Filtered Rayleigh scattering was utilized as a flow diagnostic in an investigation of a method for enhancing mixing in supersonic jets. The primary objectives of the study were to visualize the effect of vortex generating tabs on supersonic jets, to exact quantitative data from these planar visualizations, and to detect the presence of secondary flows (i.e., streamwise vorticity) generated by the tabs. An injection seeded frequency-doubled Nd:YAG was the light source and a 14 bit Princeton Instruments iodine charge coupled display (ICCD) camera recorded the image through an iodine cell. The incident wave length of the laser was held constant for each flow case so that the filter absorbed unwanted background light, but permitted part of the thermally broadened Rayleigh scattering light to pas through. The visualizations were performed for axisymmetric jets (D=1.9 cm) operated at perfectly expanded conditions for Mach 1.0, 1.5, and 2.0. All data were recorded for the jet cross section at x/D=3. One hundred instantaneous images were recorded and averaged for each case, with a threshold set to eliminate unavoidable particulate scattering. A key factor in these experiments was that the stagnation air was heated such that the expansion of the flow in the nozzle resulted in the static temperature in the jet being equal to the ambient temperature, assuming isentropic flow. Since the thermodynamic conditions of the flow were approximately the same for each case, increases in the intensity recorded by the ICCD camera could be directly attributed to the Doppler shift, and hence velocity. Visualizations were performed for Mach 1.5 and Mach 2.0 jets with tabs inserted at the nozzle exit. The distortion of the jet was readily apparent and was consistent with Mie scattering-based visualizations. Asymmetry in the intensities of the images indicate the presence of secondary flow patterns which are consistent with the streamwise vortices measured using more traditional diagnostics in subsonic jets with the same tab configurations. Because each tab causes shocks to form, the assumption of isentropic flow is not valid for these cases. However, within a reasonable first-order estimation,the intensity across the illuminated plane for these cases can be related to a value combining density and velocity.

Measurements and computational analysis of heat transfer and flow in a simulated turbine blade internal cooling passage

NASA Technical Reports Server (NTRS)

Russell, Louis M.; Thurman, Douglas R.; Simonyi, Patricia S.; Hippensteele, Steven A.; Poinsatte, Philip E.

1993-01-01

Visual and quantitative information was obtained on heat transfer and flow in a branched-duct test section that had several significant features of an internal cooling passage of a turbine blade. The objective of this study was to generate a set of experimental data that could be used to validate computer codes for internal cooling systems. Surface heat transfer coefficients and entrance flow conditions were measured at entrance Reynolds numbers of 45,000, 335,000, and 726,000. The heat transfer data were obtained using an Inconel heater sheet attached to the surface and coated with liquid crystals. Visual and quantitative flow field results using particle image velocimetry were also obtained for a plane at mid channel height for a Reynolds number of 45,000. The flow was seeded with polystyrene particles and illuminated by a laser light sheet. Computational results were determined for the same configurations and at matching Reynolds numbers; these surface heat transfer coefficients and flow velocities were computed with a commercially available code. The experimental and computational results were compared. Although some general trends did agree, there were inconsistencies in the temperature patterns as well as in the numerical results. These inconsistencies strongly suggest the need for further computational studies on complicated geometries such as the one studied.

Control of Flow Structure on Low Swept Delta Wing with Steady Leading Edge Blowing

NASA Astrophysics Data System (ADS)

Ozturk, Ilhan; Zharfa, Mohammadreza; Yavuz, Mehmet Metin

2014-11-01

Interest in unmanned combat air vehicles (UCAVs) and micro air vehicles (MAVs) has stimulated investigation of the flow structure, as well as its control, on delta wings having low and moderate values of sweep angle. In the present study, the flow structure is characterized on a delta wing of low sweep 35-degree angle, which is subjected to steady leading edge blowing. The techniques of laser illuminated smoke visualization, laser Doppler anemometry (LDA), and surface pressure measurements are employed to investigate the steady and unsteady nature of the flow structure on delta wing, in relation to the dimensionless magnitude of the blowing coefficient. Using statistics and spectral analysis, unsteadiness of the flow structure is studied in detail. Different injection locations are utilized to apply different blowing patterns in order to identify the most efficient control, which provides the upmost change in the flow structure with the minimum energy input. The study aims to find the optimum flow control strategy to delay or to prevent the stall and possibly to reduce the buffeting on the wing surface. Since the blowing set-up is computer controlled, the unsteady blowing patterns compared to the present steady blowing patterns will be studied next. This project was supported by the Scientific and Technological Research Council of Turkey (Project Number: 3501 111M732).

Optical measurement methods in thermogasdynamics

NASA Technical Reports Server (NTRS)

Stursberg, K.; Erhardt, K.; Krahr, W.; Becker, M.

1978-01-01

A review is presented of a number of optical methods of flow measurements. Consideration is given to such spectroscopic methods as emission and absorption techniques, electron beam-stimulated fluorescence, and light scattering - Rayleigh, Raman and Mie - methods. The following visualization methods are also discussed: shadow photography, schlieren photography, interferometry, holographic interferometry, laser anemometry, particle holography, and electron-excitation imaging. A large bibliography is presented and the work is copiously illustrated with figures and photographs.

Preliminary experiments on phase conjugation for flow visualization. [barium titanate single crystals

NASA Technical Reports Server (NTRS)

Weimer, D.; Howes, W. L.

1984-01-01

Barium titanate single crystals are discussed in the context of: the procedure for polarizing a crystal; a test for phase conjugation; transients in the production of phase conjugation; real time readout by a separate laser of a hologram induced within the crystal, including conjugation response times to on-off switching of each beam; and a demonstration of a Twyman-Green interferometer utilizing phase conjugation.

Experimental Investigation of the Near Wall Flow Structure of a Low Reynolds Number 3-D Turbulent Boundary Layer

NASA Technical Reports Server (NTRS)

Fleming, J. L.; Simpson, R. L.

1997-01-01

Laser Doppler velocimetry (LDV) measurements and hydrogen bubble flow visualization techniques were used to examine the near-wall flow structure of 2D and 3D turbulent boundary layers (TBLs) over a range of low Reynolds numbers. The goals of this research were (1) an increased understanding of the flow physics in the near wall region of turbulent boundary layers,(2) to observe and quantify differences between 2D and 3D TBL flow structures, and (3) to document Reynolds number effects for 3D TBLs. The LDV data have provided results detailing the turbulence structure of the 2D and 3D TBLs. These results include mean Reynolds stress distributions, flow skewing results, and U and V spectra. Effects of Reynolds number for the 3D flow were also examined. Comparison to results with the same 3D flow geometry but at a significantly higher Reynolds number provided unique insight into the structure of 3D TBLs. While the 3D mean and fluctuating velocities were found to be highly dependent on Reynolds number, a previously defined shear stress parameter was discovered to be invariant with Reynolds number. The hydrogen bubble technique was used as a flow visualization tool to examine the near-wall flow structure of 2D and 3D TBLs. Both the quantitative and qualitative results displayed larger turbulent fluctuations with more highly concentrated vorticity regions for the 2D flow.

Laser Speckle Contrast Imaging: theory, instrumentation and applications.

PubMed

Senarathna, Janaka; Rege, Abhishek; Li, Nan; Thakor, Nitish V

2013-01-01

Laser Speckle Contrast Imaging (LSCI) is a wide field of view, non scanning optical technique for observing blood flow. Speckles are produced when coherent light scattered back from biological tissue is diffracted through the limiting aperture of focusing optics. Mobile scatterers cause the speckle pattern to blur; a model can be constructed by inversely relating the degree of blur, termed speckle contrast to the scatterer speed. In tissue, red blood cells are the main source of moving scatterers. Therefore, blood flow acts as a virtual contrast agent, outlining blood vessels. The spatial resolution (~10 μm) and temporal resolution (10 ms to 10 s) of LSCI can be tailored to the application. Restricted by the penetration depth of light, LSCI can only visualize superficial blood flow. Additionally, due to its non scanning nature, LSCI is unable to provide depth resolved images. The simple setup and non-dependence on exogenous contrast agents have made LSCI a popular tool for studying vascular structure and blood flow dynamics. We discuss the theory and practice of LSCI and critically analyze its merit in major areas of application such as retinal imaging, imaging of skin perfusion as well as imaging of neurophysiology.

Virtual and Experimental Visualization of Flows in Packed Beds of Spheres Simulating Porous Media Flows

NASA Technical Reports Server (NTRS)

Hendricks, R. C.; Athavale, M. M.; Lattime, S. B.; Braun, M. J.

1998-01-01

A videotape presentation of flow in a packed bed of spheres is provided. The flow experiment consisted of three principal elements: (1) an oil tunnel 76.2 mm by 76.2 mm in cross section, (2) a packed bed of spheres in regular and irregular arrays, and (3) a flow characterization methodology, either (a) full flow field tracking (FFFT) or (b) computational fluid dynamic (CFD) simulation. The refraction indices of the oil and the test array of spheres were closely matched, and the flow was seeded with aluminum oxide particles. Planar laser light provided a two-dimensional projection of the flow field, and a traverse simulated a three-dimensional image of the entire flow field. Light focusing and reflection rendered the spheres black, permitting visualization of the planar circular interfaces in both the axial and transverse directions. Flows were observed near the wall-sphere interface and within the set of spheres. The CFD model required that a representative section of a packed bed be formed and gridded, enclosing and cutting six spheres so that symmetry conditions could be imposed at all cross-boundaries. Simulations had to be made with the flow direction at right angles to that used in the experiments, however, to take advantage of flow symmetry. Careful attention to detail was required for proper gridding. The flow field was three-dimensional and complex to describe, yet the most prominent finding was flow threads, as computed in the representative 'cube' of spheres with face symmetry and conclusively demonstrated experimentally herein. Random packing and bed voids tended to disrupt the laminar flow, creating vortices.

Visual based laser speckle pattern recognition method for structural health monitoring

NASA Astrophysics Data System (ADS)

Park, Kyeongtaek; Torbol, Marco

2017-04-01

This study performed the system identification of a target structure by analyzing the laser speckle pattern taken by a camera. The laser speckle pattern is generated by the diffuse reflection of the laser beam on a rough surface of the target structure. The camera, equipped with a red filter, records the scattered speckle particles of the laser light in real time and the raw speckle image of the pixel data is fed to the graphic processing unit (GPU) in the system. The algorithm for laser speckle contrast analysis (LASCA) computes: the laser speckle contrast images and the laser speckle flow images. The k-mean clustering algorithm is used to classify the pixels in each frame and the clusters' centroids, which function as virtual sensors, track the displacement between different frames in time domain. The fast Fourier transform (FFT) and the frequency domain decomposition (FDD) compute the modal properties of the structure: natural frequencies and damping ratios. This study takes advantage of the large scale computational capability of GPU. The algorithm is written in Compute Unifies Device Architecture (CUDA C) that allows the processing of speckle images in real time.

Ocular dynamics and visual tracking performance after Q-switched laser exposure

NASA Astrophysics Data System (ADS)

Zwick, Harry; Stuck, Bruce E.; Lund, David J.; Nawim, Maqsood

2001-05-01

In previous investigations of q-switched laser retinal exposure in awake task oriented non-human primates (NHPs), the threshold for retinal damage occurred well below that of the threshold for permanent visual function loss. Visual function measures used in these studies involved measures of visual acuity and contrast sensitivity. In the present study, we examine the same relationship for q-switched laser exposure using a visual performance task, where task dependency involves more parafoveal than foveal retina. NHPs were trained on a visual pursuit motor tracking performance task that required maintaining a small HeNe laser spot (0.3 degrees) centered in a slowly moving (0.5deg/sec) annulus. When NHPs reliably produced visual target tracking efficiencies > 80%, single q-switched laser exposures (7 nsec) were made coaxially with the line of sight of the moving target. An infrared camera imaged the pupil during exposure to obtain the pupillary response to the laser flash. Retinal images were obtained with a scanning laser ophthalmoscope 3 days post exposure under ketamine and nembutol anesthesia. Q-switched visible laser exposures at twice the damage threshold produced small (about 50mm) retinal lesions temporal to the fovea; deficits in NHP visual pursuit tracking were transient, demonstrating full recovery to baseline within a single tracking session. Post exposure analysis of the pupillary response demonstrated that the exposure flash entered the pupil, followed by 90 msec refractory period and than a 12 % pupillary contraction within 1.5 sec from the onset of laser exposure. At 6 times the morphological threshold damage level for 532 nm q-switched exposure, longer term losses in NHP pursuit tracking performance were observed. In summary, q-switched laser exposure appears to have a higher threshold for permanent visual performance loss than the corresponding threshold to produce retinal threshold injury. Mechanisms of neural plasticity within the retina and at higher visual brain centers may mediat

Flow Quantification by Nuclear Magnetic Resonance Imaging

NASA Astrophysics Data System (ADS)

Vu, Anthony Tienhuan

1994-01-01

In this dissertation, a robust method for the measurement and visualization of flow field in laminar, complex and turbulent flows by Nuclear Magnetic Resonance Imaging utilizing flow induced Adiabatic Fast Passage (AFP) principle will be presented. This dissertation focuses on the application of AFP in spatially resolvable size vessels. We first review two main flow effects in NMR: time-of-flight and phase dispersion. The discussion of NMR flow imaging application - flow measurements and NMR angiography will be given. The theoretical framework of adiabatic passage will be discussed in order to explain the principle of flow-induced adiabatic passage tagging for flow imaging applications. From a knowledge of the basic flow-induced adiabatic passage principle, we propose a multi-zone AFP excitation scheme to deal with flow in a curved tube, branches and constrictions, i.e. complex and turbulent flow regimes. The technique provides a quick and simple way to acquire flow profiles simultaneously at several locations and arbitrary orientations inside the field-of-view. The flow profile is the time-averaged evolution of the labeled flowing material. Results obtained using a carotid bifurcation and circular jet phantoms are similar to the previous experimental studies employing laser Doppler Anemometry, and other flow visualization techniques. In addition, the preliminary results obtained with a human volunteer support the feasibility of the technique for in vivo flow quantification. Finally, a quantitative comparison of flow measurement of the new proposed techniques with the more established Phase Contrast MRA was performed. The results show excellent correlation between the two methods and with the standard volumetric flow rate measurement indicating that the flow measurements obtained using this technique are reliable and accurate under various flow regimes.

Definition of the unsteady vortex flow over a wing/body configuration

NASA Technical Reports Server (NTRS)

Liou, S. G.; Debry, B.; Lenakos, J.; Caplin, J.; Komerath, N. M.

1991-01-01

A problem of current interest in computational aerodynamics is the prediction of unsteady vortex flows over aircraft at high angles of attack. A six-month experimental effort was conducted at the John H. Harper Wind Tunnel to acquire qualitative and quantitative information on the unsteady vortex flow over a generic wing-body configuration at high angles of attack. A double-delta flat-plate wing with beveled edges was combined with a slender sharp-nosed body-of-revolution fuselage to form the generic configuration. This configuration produces a strong attached leading edge vortex on the wing, as well as sharply-peaked flow velocity spectra above the wing. While it thus produces flows with several well-defined features of current interest, the model was designed for efficiency of representation in computational codes. A moderate number of surface pressure ports and two unsteady pressure sensors were used to study the pressure distribution over the wing and body surface at high angles of attack; the unsteady pressure sensing did not succeed because of inadequate signal-to-noise ratio. A pulsed copper vapor laser sheet was used to visualize the vortex flow over the model, and vortex trajectories, burst locations, mutual induction of vortex systems from the forebody, strake, and wing, were quantified. Laser Doppler velocimetry was used to quantify all 3 components of the time-average velocity in 3 data planes perpendicular to the freestream direction. Statistics of the instantaneous velocity were used to study intermittency and fluctuation intensity. Hot-film anemometry was used to study the fluctuation energy content in the velocity field, and the spectra of these fluctuations. In addition, a successful attempt was made to measure velocity spectra, component by component, using laser velocimetry, and these were compared with spectra measured by hot-film anemometry at several locations.

An Experimental Investigation of the Flow Over the Rear End of a Notchback Automobile Configuration

NASA Technical Reports Server (NTRS)

Jenkins, Luther N.

2000-01-01

An experimental investigation of the flow over the rear end of a 0.16 scale notchback automobile configuration has been conducted in the NASA Langley Basic Aerodynamics Research Tunnel (BART). The objective of this work was to investigate the flow separation that occurs behind the backlight and obtain experimental data that can be used to understand the physics and time-averaged structure of the flow field. A three-component laser velocimeter was used to make non-intrusive, velocity measurements in the center plane and in a single cross-flow plane over the decklid. In addition to off-body measurements, flow conditions on the car surface were documented via surface flow visualization, boundary layer measurements, and surface pressures. The experimental data show several features previously identified by other researchers, but also reveal differences between the flow field associated with this particular configuration and the generally accepted models for the flow over a notchback rear end.

Laser Speckle Imaging of Blood Flow Beneath Static Scattering Media

NASA Astrophysics Data System (ADS)

Regan, Caitlin Anderson

Laser speckle imaging (LSI) is a wide-field optical imaging technique that provides information about the movement of scattering particles in biological samples. LSI is used to create maps of relative blood flow and perfusion in samples such as the skin, brain, teeth, gingiva, and other biological tissues. The presence of static, or non-moving, optical scatterers affects the ability of LSI to provide true quantitative and spatially resolved measurements of blood flow. With in vitro experiments using tissue-simulating phantoms, we determined that temporal analysis of raw speckle image sequences improved the quantitative accuracy of LSI to measure flow beneath a static scattering layer. We then applied the temporal algorithm to assess the potential of LSI to monitor oral health. We designed and tested two generations of miniature LSI devices to measure flow in the pulpal chamber of teeth and in the gingiva. Our preliminary clinical pilot data indicated that speckle contrast may correlate with gingival health. To improve visualization of subsurface blood vessels, we developed a technique called photothermal LSI. We applied a short pulse of laser energy to selectively perturb the motion of red blood cells, increasing the signal from vasculature relative to the surroundings. To study the spectral and depth dependence of laser speckle contrast, we developed a Monte Carlo model of light and momentum transport to simulate speckle contrast. With an increase in the thickness of the overlying static-scattering layer, we observed a quadratic decrease in the quantity of dynamically scattered light collected by the detector. We next applied the model to study multi-exposure speckle imaging (MESI), a method that purportedly improves quantitative accuracy of subsurface blood flow measurements. We unexpectedly determined that MESI faced similar depth limitations as conventional LSI, findings that were supported by in vitro experimental data. Finally, we used the model to study the effects of epidermal melanin absorption on LSI, and demonstrated that speckle contrast is less sensitive to varying melanin content than reflectance. We then proposed a two-wavelength measurement protocol that may enable melanin-independent LSI measurements of blood flow in patients with varying skin types. In conclusion, through in vitro and in silico experiments, we were able to further the understanding of the depth dependent origins of laser speckle contrast as well as the inherent limitations of this technology.

Vortices revealed: Swimming faster

NASA Astrophysics Data System (ADS)

van Houwelingen, Josje; van de Water, Willem; Kunnen, Rudie; van Heijst, Gertjan; Clercx, Herman

2016-11-01

Understanding and optimizing the propulsion in human swimming requires insight into the hydrodynamics of the flow around the swimmer. Experiments and simulations addressing the hydrodynamics of swimming have been conducted in studies before, including the visualization of the flow using particle image velocimetry (PIV). The main objective in this study is to develop a system to visualize the flow around a swimmer in practice inspired by this technique. The setup is placed in a regular swimming pool. The use of tracer particles and lasers to illuminate the particles is not allowed. Therefore, we choose to work with air bubbles with a diameter of 4 mm, illuminated by ambient light. Homogeneous bubble curtains are produced by tubes implemented in the bottom of the pool. The bubble motion is captured by six cameras placed in underwater casings. A first test with the setup has been conducted by pulling a cylinder through the bubbles and performing a PIV analysis. The vorticity plots of the resulting data show the expected vortex street behind the cylinder. The shedding frequency of the vortices resembles the expected frequency. Thus, it is possible to identify and follow the coherent structures. We will discuss these results and the first flow measurements around swimmers.

Chemical Reactions in Turbulent Mixing Flows.

DTIC Science & Technology

1986-04-10

fluctuation of the " flame " length of such reactingjeatreent wer copoit sequencd shout tnhawate facility, documented previously’,’ 1 , using laser jets. A...motion film of such a chemically reacting turbulent jet visualized using this technique, is shown in figure 1. In each I. Flame length fluctuations of...acid-base reaction to determine length and time to allow a simultaneous view of mixing in the two scales for the flame length fluctuations of thin

Laser-Based Optical System for Reactive Radical Concentration Measurements in Plasmas and Flames

DTIC Science & Technology

2006-08-01

role of different plasma components in chain propagation support: (1) and (2) - corona plasma generators with high-voltage multiple needle electrodes ; (3...H20 2) and HCN. Measurements in Gliding Arc, Dielectric Barrier Discharge and Pulsed Corona Plasma systems and in flame and flow reactor systems are...discharges operating in air with iron electrodes - 260V.35 Using visual quantification from high speed camera arc images, the approximate thickness of

Evaluation of some technical factors affecting surgical outcome in photorefractive keratectomy with the VISX 2020 excimer laser

NASA Astrophysics Data System (ADS)

Maguen, Ezra I.; Salz, James J.; Papaioannou, Thanassis; Nesburn, Anthony B.

1995-05-01

Some technical factors relating to the use of the VISX model 20/20 excimer laser for photorefractive keratectomy will be discussed and the way they affect the final optical correction will be demonstrated, as follows: (1) Discontinuation of nitrogen flow: improved corneal haze but induced a mean undercorrection of 0.8 D, 18 months postoperatively. (2) Discontinuation of the use of the fixation ring did not affect centration in a statistically significant fashion. (3) Enlargement of the optical from 5.0 mm to 6.0 mm zone did not affect the refractive outcome. Visual acuity was improved in eyes which had PRK done with a 6.0 mm optical zone.

Correlation of a scanning laser derived oedema index and visual function following grid laser treatment for diabetic macular oedema.

PubMed

Hudson, C; Flanagan, J G; Turner, G S; Chen, H C; Young, L B; McLeod, D

2003-04-01

To correlate change of an oedema index derived by scanning laser tomography with change of visual function in patients undergoing grid laser photocoagulation for clinically significant diabetic macular oedema (DMO). The sample comprised 24 diabetic patients with retinal thickening within 500 micro m of the fovea. Inclusion criteria included a logMAR visual acuity of 0.25, or better. Patients were assessed twice before a single session of grid laser treatment and within 1 week of, and at 1, 2, 4, and 12 weeks after, treatment. At each visit, patients underwent logMAR visual acuity, conventional and short wavelength automated perimetry (SWAP), and scanning laser tomography. Each visual function parameter was correlated with the mean oedema index. The mean oedema index represented the z-profile signal width divided by the maximum reflectance intensity (arbitrary units). A Pearson correlation coefficient (Bonferroni corrected) was undertaken on the data set of each patient. 13 patients exhibited significant correlation of the mean oedema index and at least one measure of visual function for the 10 degrees x 10 degrees scan field while 10 patients correlated for the 20 degrees x 20 degrees scan field. Seven patients demonstrated correlation for both scan fields. Laser photocoagulation typically resulted in an immediate loss of perimetric sensitivity whereas the oedema index changed over a period of weeks. Localised oedema did not impact upon visual acuity or letter contrast sensitivity when situated extrafoveally. Correlation of change of the oedema index and of visual function following grid laser photocoagulation was not found in all patients. An absence of correlation can be explained by the localised distribution of DMO in this sample of patients, as well as by differences in the time course of change of the oedema index and visual function. The study has objectively documented change in the magnitude and distribution of DMO following grid laser treatment and has established the relation of this change to the change in visual function.

Effect of neodymium:YAG laser capsulotomy on visual function in patients with posterior capsule opacification and good visual acuity.

PubMed

Yotsukura, Erisa; Torii, Hidemasa; Saiki, Megumi; Negishi, Kazuno; Tsubota, Kazuo

2016-03-01

To evaluate the effect of neodymium:YAG (Nd:YAG) laser capsulotomy on the visual function in patients with posterior capsule opacification (PCO) and good visual acuity. Keio University Hospital, Tokyo, Japan. Observational case series. Eyes were evaluated that had previous cataract surgery with a clinical diagnosis of PCO requiring Nd:YAG laser capsulotomy regardless of a good corrected distance visual acuity (CDVA) (at least 20/20). The CDVA, 10% low contrast visual acuity (LCVA), wavefront aberrations from the 3rd to 6th order, and retinal straylight were measured before and after Nd:YAG laser capsulotomy. The study included 16 eyes of 16 patients (10 men, 6 women; mean age 69.5 years ± 9.3 [SD]). The mean CDVA, LCVA, and straylight after Nd:YAG laser capsulotomy improved significantly (P < .05). The root mean square (RMS) of the 3rd Zernike coefficients (S3) and the RMS of the total higher-order aberrations (HOAs) from the 3rd to 6th order decreased significantly after capsulotomy (P < .05). The straylight correlated significantly with the total HOAs (r = 0.727, P = .002) and S3 (r = 0.748, P = .001) before capsulotomy. Subjective symptoms resolved after capsulotomy in all cases. Neodymium:YAG laser capsulotomy enabled a significant improvement in visual function even in patients with PCO with good visual acuity. Straylight measurements might be useful to determine the indications for Nd:YAG laser capsulotomy when patients report visual disturbances without decreased visual acuity. Copyright © 2016 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

21 CFR 886.1360 - Visual field laser instrument.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Visual field laser instrument. 886.1360 Section 886.1360 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES OPHTHALMIC DEVICES Diagnostic Devices § 886.1360 Visual field laser instrument...

Bubble Dynamics on a Heated Surface

NASA Technical Reports Server (NTRS)

Kassemi, Mohammad; Rashidnia, Nasser

1996-01-01

In this work, we study the combined thermocapillary and natural convective flow generated by a bubble on a heated solid surface. The interaction between gas and vapor bubbles with the surrounding fluid is of interest for both space and ground-based processing. On earth, the volumetric forces are dominant, especially, in apparatuses with large volume to surface ratio. But in the reduced gravity environment of orbiting spacecraft, surface forces become more important and the effects of Marangoni convection are easily unmasked. In order to delineate the roles of the various interacting phenomena, a combined numerical-experimental approach is adopted. The temperature field is visualized using Mach-Zehnder interferometry and the flow field is observed by a laser sheet flow visualization technique. A finite element numerical model is developed which solves the two-dimensional momentum and energy equations and includes the effects of bubble surface deformation. Steady state temperature and velocity fields predicted by the finite element model are in excellent qualitative agreement with the experimental results. A parametric study of the interaction between Marangoni and natural convective flows including conditions pertinent to microgravity space experiments is presented. Numerical simulations clearly indicate that there is a considerable difference between 1-g and low-g temperature and flow fields induced by the bubble.

Wind Tunnel Investigation of Passive Vortex Control and Vortex-Tail Interactions on a Slender Wing at Subsonic and Transonic Speeds

NASA Technical Reports Server (NTRS)

Erickson, Gary E.

2013-01-01

A wind tunnel experiment was conducted in the NASA Langley 8-Foot Transonic Pressure Tunnel to determine the effects of passive porosity on vortex flow interactions about a slender wing configuration at subsonic and transonic speeds. Flow-through porosity was applied in several arrangements to a leading-edge extension, or LEX, mounted to a 65-degree cropped delta wing as a longitudinal instability mitigation technique. Test data were obtained with LEX on and off in the presence of a centerline vertical tail and twin, wing-mounted vertical fins to quantify the sensitivity of the aerodynamics to tail placement and orientation. A close-coupled canard was tested as an alternative to the LEX as a passive flow control device. Wing upper surface static pressure distributions and six-component forces and moments were obtained at Mach numbers of 0.50, 0.85, and 1.20, unit Reynolds number of 2.5 million, angles of attack up to approximately 30 degrees, and angles of sideslip to +/-8 degrees. The off-surface flow field was visualized in cross planes on selected configurations using a laser vapor screen flow visualization technique. Tunnel-to-tunnel data comparisons and a Reynolds number sensitivity assessment were also performed. 15.

Atomic force microscopy visualization of injuries in Enterococcus faecalis surface caused by Er,Cr:YSGG and diode lasers

PubMed Central

López-Jiménez, Lidia; Viñas, Miguel; Vinuesa, Teresa

2015-01-01

Aim: To visualize by Atomic Force Microscopy the alterations induced on Enterococcus. faecalis surface after treatment with 2 types of laser: Erbium chromium:yttrium-scandium-gallium-garnet (Er,Cr:YSGG) laser and Diode laser. Material and Methods: Bacterial suspensions from overnight cultures of E. faecalis were irradiated during 30 seconds with the laser-lights at 1 W and 2 W of power, leaving one untreated sample as control. Surface alterations on treated E. faecalis were visualized by Atomic Force Microscopy (AFM) and its surface roughness determined. Results: AFM imaging showed that at high potency of laser both cell morphology and surface roughness resulted altered, and that several cell lysis signs were easily visualized. Surface roughness clearly increase after the treatment with Er,Cr:YSGG at 2W of power, while the other treatments gave similar values of surface roughness. The effect of lasers on bacterial surfaces visualized by AFM revealed drastic alterations. Conclusions: AFM is a good tool to evaluate surface injuries after laser treatment; and could constitute a measure of antimicrobial effect that can complete data obtained by determination of microbial viability. Key words:Atomic force microscopy, Er,Cr:YSGG laser, diode laser, Enterococcus faecalis, surface roughness. PMID:25475770

Comparison of Indocyanine Green Angiography and Laser Speckle Contrast Imaging for the Assessment of Vasculature Perfusion

PubMed Central

Towle, Erica L.; Richards, Lisa M.; Kazmi, S. M. Shams; Fox, Douglas J.; Dunn, Andrew K.

2013-01-01

BACKGROUND Assessment of the vasculature is critical for overall success in cranial vascular neurological surgery procedures. Although several methods of monitoring cortical perfusion intraoperatively are available, not all are appropriate or convenient in a surgical environment. Recently, 2 optical methods of care have emerged that are able to obtain high spatial resolution images with easily implemented instrumentation: indocyanine green (ICG) angiography and laser speckle contrast imaging (LSCI). OBJECTIVE To evaluate the usefulness of ICG and LSCI in measuring vessel perfusion. METHODS An experimental setup was developed that simultaneously collects measurements of ICG fluorescence and LSCI in a rodent model. A 785-nm laser diode was used for both excitation of the ICG dye and the LSCI illumination. A photothrombotic clot model was used to occlude specific vessels within the field of view to enable comparison of the 2 methods for monitoring vessel perfusion. RESULTS The induced blood flow change demonstrated that ICG is an excellent method for visualizing the volume and type of vessel at a single point in time; however, it is not always an accurate representation of blood flow. In contrast, LSCI provides a continuous and accurate measurement of blood flow changes without the need of an external contrast agent. CONCLUSION These 2 methods should be used together to obtain a complete understanding of tissue perfusion. PMID:22843129

Development of a Pulsed Combustion Actuator For High-Speed Flow Control

NASA Technical Reports Server (NTRS)

Cutler, Andrew D.; Beck, B. Terry; Wilkes, Jennifer A.; Drummond, J. Philip; Alderfer, David W.; Danehy, Paul M.

2005-01-01

This paper describes the flow within a prototype actuator, energized by pulsed combustion or detonations, that provides a pulsed jet suitable for flow control in high-speed applications. A high-speed valve, capable of delivering a pulsed stream of reactants a mixture of H2 and air at rates of up to 1500 pulses per second, has been constructed. The reactants burn in a resonant chamber, and the products exit the device as a pulsed jet. High frequency pressure transducers have been used to monitor the pressure fluctuations in the device at various reactant injection frequencies, including both resonant and off-resonant conditions. The combustion chamber has been constructed with windows, and the flow inside it has been visualized using Planar Laser-Induced Fluorescence (PLIF). The pulsed jet at the exit of the device has been observed using schlieren.

Cavitation bubble nucleation induced by shock-bubble interaction in a gelatin gel

NASA Astrophysics Data System (ADS)

Oguri, Ryota; Ando, Keita

2018-05-01

An optical visualization technique is developed to study cavitation bubble nucleation that results from interaction between a laser-induced shock and a preexisting gas bubble in a 10 wt. % gelatin gel; images of the nucleated cavitation bubbles are captured and the cavitation inception pressure is determined based on Euler flow simulation. A spherical gas cavity is generated by focusing an infrared laser pulse into a gas-supersaturated gel and the size of the laser-generated bubble in mechanical equilibrium is tuned via mass transfer of the dissolved gas into the bubble. A spherical shock is then generated, through rapid expansion of plasma induced by the laser focusing, in the vicinity of the gas bubble. The shock-bubble interaction is recorded by a CCD camera with flash illumination of a nanosecond green laser pulse. The observation captures cavitation inception in the gel under tension that results from acoustic impedance mismatching at the bubble interface interacting with the shock. We measure the probability of cavitation inception from a series of the repeated experiments, by varying the bubble radius and the standoff distance. The threshold pressure is defined at the cavitation inception probability equal to one half and is calculated, through comparisons to Euler flow simulation, at -24.4 MPa. This threshold value is similar to that from shock-bubble interaction experiments using water, meaning that viscoelasticity of the 10 wt. % gelatin gel has a limited impact on bubble nucleation dynamics.

Effects of boundary-layer separation controllers on a desktop fume hood.

PubMed

Huang, Rong Fung; Chen, Jia-Kun; Hsu, Ching Min; Hung, Shuo-Fu

2016-10-02

A desktop fume hood installed with an innovative design of flow boundary-layer separation controllers on the leading edges of the side plates, work surface, and corners was developed and characterized for its flow and containment leakage characteristics. The geometric features of the developed desktop fume hood included a rearward offset suction slot, two side plates, two side-plate boundary-layer separation controllers on the leading edges of the side plates, a slanted surface on the leading edge of the work surface, and two small triangular plates on the upper left and right corners of the hood face. The flow characteristics were examined using the laser-assisted smoke flow visualization technique. The containment leakages were measured by the tracer gas (sulphur hexafluoride) detection method on the hood face plane with a mannequin installed in front of the hood. The results of flow visualization showed that the smoke dispersions induced by the boundary-layer separations on the leading edges of the side plates and work surface, as well as the three-dimensional complex flows on the upper-left and -right corners of the hood face, were effectively alleviated by the boundary-layer separation controllers. The results of the tracer gas detection method with a mannequin standing in front of the hood showed that the leakage levels were negligibly small (≤0.003 ppm) at low face velocities (≥0.19 m/s).

An investigation of the effects of spanwise wall oscillation on the structure of a turbulent boundary layer

NASA Astrophysics Data System (ADS)

Trujillo, Steven Mathew

Transition of a fluid boundary layer from a laminar to a turbulent regime is accompanied by a large increase in skin friction drag. The ability to manipulate the flow or its bounding geometry to reduce this drag effectively has been a long-sought goal in contemporary fluid mechanics. Recently, workers have demonstrated that continuous lateral oscillation of the flow's bounding surface is one means to this goal, producing significant drag reduction. The present study was performed to understand better the mechanism by which such a flow achieves drag reduction. An oscillating wall section was installed in a water channel facility, and the resulting flow was studied using laser Doppler velocimetry, hot-film anemometry, and visualization techniques. Traditional mean and fluctuating statistics were examined, as well as statistics computed from conditionally-sampled turbulent events. The dependence of these quantities on the phase of the oscillating surface's motion was also studied. Visualization-based studies were employed to provide insight into the structural changes brought on by the wall oscillation. The most dramatic changes effected by the wall motion were seen as reductions in frequency of bursts and sweeps, events which concentrate large production of Reynolds stress and which ultimately augment wall skin friction. These Reynolds-stress reductions were reflected in reductions in mean and fluctuating quantifies in the lower regions of the boundary layer. Other velocity measurements confirmed earlier workers' speculations that the secondary flow induced by the oscillating wall is comparable to Stokes' solution for an oscillating plate in a quiescent fluid. Other than this secondary flow, however, the boundary layer displayed essentially no dependence on the phase of the wall motion. A simple cost analysis showed that, in general, the energy cost required to implement this technique is greater than the savings it produces. The visualizations of the flow revealed a more uniform flow in the near-wall region resulting from wall oscillation. Quantitative analyses of the visualizations supported the velocity-based Reynolds-stress reductions; the same data also revealed that the quasi-streamwise vortical structures above the wall did not appear to be altered significantly by the wall motion.

Laser speckle imaging identification of increases in cortical microcirculatory blood flow induced by motor activity during awake craniotomy.

PubMed

Klijn, Eva; Hulscher, Hester C; Balvers, Rutger K; Holland, Wim P J; Bakker, Jan; Vincent, Arnaud J P E; Dirven, Clemens M F; Ince, Can

2013-02-01

The goal of awake neurosurgery is to maximize resection of brain lesions with minimal injury to functional brain areas. Laser speckle imaging (LSI) is a noninvasive macroscopic technique with high spatial and temporal resolution used to monitor changes in capillary perfusion. In this study, the authors hypothesized that LSI can be useful as a noncontact method of functional brain mapping during awake craniotomy for tumor removal. Such a modality would be an advance in this type of neurosurgery since current practice involves the application of invasive intraoperative single-point electrocortical (electrode) stimulation and measurements. After opening the dura mater, patients were woken up, and LSI was set up to image the exposed brain area. Patients were instructed to follow a rest-activation-rest protocol in which activation consisted of the hand-clenching motor task. Subsequently, exposed brain areas were mapped for functional motor areas by using standard electrocortical stimulation (ECS). Changes in the LSI signal were analyzed offline and compared with the results of ECS. In functional motor areas of the hand mapped with ECS, cortical blood flow measured using LSI significantly increased from 2052 ± 818 AU to 2471 ± 675 AU during hand clenching, whereas capillary blood flow did not change in the control regions (areas mapped using ECS with no functional activity). The main finding of this study was that changes in laser speckle perfusion as a measure of cortical microvascular blood flow when performing a motor task with the hand relate well to the ECS map. The authors have shown the feasibility of using LSI for direct visualization of cortical microcirculatory blood flow changes during neurosurgery.

Laser Optometric Assessment Of Visual Display Viewability

NASA Astrophysics Data System (ADS)

Murch, Gerald M.

1983-08-01

Through the technique of laser optometry, measurements of a display user's visual accommodation and binocular convergence were used to assess the visual impact of display color, technology, contrast, and work time. The studies reported here indicate the potential of visual-function measurements as an objective means of improving the design of visual displays.

Effects of malicious ocular laser exposure in commercial airline pilots.

PubMed

Palakkamanil, Mathew M; Fielden, Michael P

2015-12-01

Intentional malicious laser strikes on commercial pilots are committed by individuals who target a laser into airplane cockpits during takeoff and landing. Because laser exposure to pilots is a relatively new but growing occurrence, our study investigates the ocular effect of this laser exposure in pilots. Retrospective chart review by a single ophthalmologist. All commercial airline pilots (58 male, 3 female) who experienced a laser strike while flying between April 2012 and November 2014 who presented to our clinic were included. A retrospective chart review was performed in a retinal specialist's practice. Ocular assessment was performed within 3 days of laser exposure. A complete ophthalmic evaluation was conducted, including Early Treatment Diabetic Retinopathy Study visual acuity, colour vision, visual fields, intraocular pressure, slit-lamp examination, dilated fundus examination, colour fundus photographs, and ocular coherence tomography. Sixty-four laser strike incidents involving commercial pilots were included. All pilots in the study experienced some degree of immediate ocular irritation or light sensitivity. No definite cases of ocular damage were attributed to laser strikes. No pilot had any functional ocular deficits. Our study revealed that laser strikes on aircraft did not result in permanent visual functional or structural deficits. However, laser strikes cause immediate visual effects, including glare, flash blindness, and ocular irritation that can interfere with a pilot's visual function. Given the widespread accessibility of high-power lasers and the rapid increase in incidents, laser strikes threaten to jeopardize aviation safety unless effective preventative measures are put in place. Copyright © 2015 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.

Wavefront-optimized laser in situ keratomileusis with the Allegretto Wave Eye-Q excimer laser and the FEMTO LDV Crystal Line femtosecond laser: 6 month visual and refractive results.

PubMed

Ziaei, Mohammed; Mearza, Ali A; Allamby, David

2015-08-01

To present the first reported series of patients undergoing myopic LASIK with the FEMTO LDV Crystal Line femtosecond laser and the WaveLight Allegretto Eye-Q excimer laser. We report the uncorrected and corrected distance visual acuity (UDVA and CDVA), refractive predictability, efficacy and safety of laser in situ keratomileusis (LASIK) performed with the above laser platforms. This prospective interventional case series study evaluated consecutive eyes with low to moderate myopic astigmatism that underwent LASIK with the FEMTO LDV Crystal Line femtosecond laser and the WaveLight Allegretto Eye-Q 400 Hz excimer laser. Visual and refractive changes as well as complications were evaluated after wavefront-optimized laser treatment. Four hundred and forty four patients (887 eyes) reached the 6-month time gate. Mean age at time of procedure was 31 years (range: 20-59). Mean pre-op spherical-equivalent (SE) was -3.44 diopters (D)±1.34D (range: -0.50 to -7.00) whilst the postoperative spherical equivalent decreased to -0.08±0.31D (range -2.25 to 1.00). At 6-month follow up, 96.9% of patients had monocular uncorrected distance visual acuity of 20/20 or better with 95.2% of patients within ±0.5D of intended refractive outcome. All patients achieved 20/20 binocular distance uncorrected visual acuity. No significant intra-operative or postoperative complications were encountered during the 6-month follow-up period. The combination of the above laser platforms provides safe, effective and predictable results in correcting compound myopic astigmatism with excellent visual outcomes. Copyright © 2015 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.

Evaluation of laser therapy and alpha-lipoic acid for the treatment of burning mouth syndrome: a randomized clinical trial.

PubMed

Barbosa, Natália Guimarães; Gonzaga, Amanda Katarinny Goes; de Sena Fernandes, Luzia Leiros; da Fonseca, Aldilane Gonçalves; Queiroz, Salomão Israel Monteiro Lourenço; Lemos, Telma Maria Araújo Moura; da Silveira, Éricka Janine Dantas; de Medeiros, Ana Miryam Costa

2018-03-03

The aim of this study was to evaluate the efficacy of low-level laser therapy (LLLT) and alpha-lipoic acid (ALA) in the treatment of burning mouth syndrome (BMS) and secondary oral burning (SOB) by unstimulated sialometry, symptom assessment, and measurement of salivary TNF-α levels. Forty-four patients were randomized into four treatment groups: BMS/laser (n = 10), BMS/ALA (n = 5), SOB/laser (n = 15), and SOB/ALA (n = 14). The control group consisted of eight healthy female subjects. Unstimulated salivary flow was measured before and after treatment, and the collected saliva was stored at - 20 °C for the analysis of TNF-α. Symptoms were evaluated before and after treatment using a pain visual analog scale. Most patients were women (81.8%) during menopause (72.2%). LLLT and ALA were efficient in increasing salivary flow only in BMS but provided symptom relief in both conditions. TNF-α levels did not differ between patients with BMS and SOB or between those patients and the control group. No differences were observed in posttreatment TNF-α levels in either condition. The results of this study suggest that LLLT and ALA are efficient therapies in reducing burning mouth symptoms, with LLLT being more efficient than ALA.

The forward masking effects of low-level laser glare on target location performance in a visual search task

NASA Astrophysics Data System (ADS)

Reddix, M. D.; Dandrea, J. A.; Collyer, P. D.

1992-01-01

The present study examined the effects of low-intensity laser glue, far below a level that would cause ocular damage or flashblindness, on the visually guided performance of aviators. With a forward-masking paradigm, this study showed that the time at which laser glare is experienced, relative to initial acquisition of visual information, differentially affects the speed and accuracy of target-location performance. Brief exposure (300 ms) to laser glare, terminating with a visual scene's onset, produced significant decrements in target-location performance relative to a no-glare control whereas a 150 and 300-ms delay of display onset (DDO) had very little effect. The intensity of the light entering the eye and producing these effects was far below the Maximum Permissible Exposure (MPE) limit for safe viewing of coherent light produced by an argon laser. In addition, these effects were modulated by the distance of the target from the center of the visual display. This study demonstrated that the presence of laser glare is not sufficient, in and of itself, to diminish target-location performance. The time at which laser glare is experienced is an important factor in determining the probability and extent of visually mediated performance decrements.

Experimental Study of Flow in a Bifurcation

NASA Astrophysics Data System (ADS)

Fresconi, Frank; Prasad, Ajay

2003-11-01

An instability known as the Dean vortex occurs in curved pipes with a longitudinal pressure gradient. A similar effect is manifest in the flow in a converging or diverging bifurcation, such as those found in the human respiratory airways. The goal of this study is to characterize secondary flows in a bifurcation. Particle image velocimetry (PIV) and laser-induced fluorescence (LIF) experiments were performed in a clear, plastic model. Results show the strength and migration of secondary vortices. Primary velocity features are also presented along with dispersion patterns from dye visualization. Unsteadiness, associated with a hairpin vortex, was also found at higher Re. This work can be used to assess the dispersion of particles in the lung. Medical delivery systems and pollution effect studies would profit from such an understanding.

Visualization of Pulmonary Clearance Mechanisms via Noninvasive Optical Imaging Validated by Near-Infrared Flow Cytometry

PubMed Central

Zhou, Haiying; Gunsten, Sean P.; Zhegalova, Natalia G.; Bloch, Sharon; Achilefu, Samuel; Holley, J. Christopher; Schweppe, Daniel; Akers, Walter; Brody, Steven L.; Eades, William; Berezin, Mikhail Y.

2016-01-01

In vivo optical imaging with near-infrared (NIR) probes is an established method of diagnostics in preclinical and clinical studies. However, the specificities of these probes are difficult to validate ex vivo due to the lack of NIR flow cytometry. To address this limitation, we modified a flow cytometer to include an additional NIR channel using a 752 nm laser line. The flow cytometry system was tested using NIR microspheres and cell lines labeled with a combination of visible range and NIR fluorescent dyes. The approach was verified in vivo in mice evaluated for immune response in lungs after intratracheal delivery of the NIR contrast agent. Flow cytometry of cells obtained from the lung bronchoalveolar lavage demonstrated that the NIR dye was taken up by pulmonary macrophages as early as four-hours post-injection. This combination of optical imaging with NIR flow cytometry extends the capability of imaging and enables complementation of in vivo imaging with cell-specific studies. PMID:25808737

Three-dimensional imaging of absolute blood flow velocity and blood vessel position under low blood flow velocity based on Doppler signal information included in scattered light from red blood cells

NASA Astrophysics Data System (ADS)

Kyoden, Tomoaki; Akiguchi, Shunsuke; Tajiri, Tomoki; Andoh, Tsugunobu; Hachiga, Tadashi

2017-11-01

The development of a system for in vivo visualization of occluded distal blood vessels for diabetic patients is the main target of our research. We herein describe two-beam multipoint laser Doppler velocimetry (MLDV), which measures the instantaneous multipoint flow velocity and can be used to observe the blood flow velocity in peripheral blood vessels. By including a motorized stage to shift the measurement points horizontally and in the depth direction while measuring the velocity, the path of the blood vessel in the skin could be observed using blood flow velocity in three-dimensional space. The relationship of the signal power density between the blood vessel and the surrounding tissues was shown and helped us identify the position of the blood vessel. Two-beam MLDV can be used to simultaneously determine the absolute blood flow velocity distribution and identify the blood vessel position in skin.

Pediatric Bilateral Blue Laser Pointer-Induced Maculopathy

PubMed Central

Raevis, Joseph; Shrier, Eric

2017-01-01

Background We report the first case of pediatric bilateral blue laser pointer maculopathy with complete resolution of visual symptoms. Case A 12-year-old boy presented with bilateral decreased visual acuity and central scotomata after blue laser pointer exposure. He was treated with a Medrol Dosepak and topical nonsteroidal anti-inflammatory drug (NSAID), with gradual visual acuity improved from 20/40 OU to 20/20 OU over 22 weeks, but with persistent evidence of outer retinal layer disruption from the external limiting membrane to the interdigitation zone. Conclusion Oral steroids and topical NSAIDs may be effective in improving visual outcomes in laser pointer maculopathy in the pediatric population. PMID:28611647

Mixing Process in Ejector Nozzles Studied at Lewis' Aero-Acoustic Propulsion Laboratory

NASA Technical Reports Server (NTRS)

1996-01-01

The NASA Lewis Research Center has been studying mixing processes in ejector nozzles for its High Speed Research (HSR) Program. This work is directed at finding ways to minimize the noise of a future supersonic airliner. Much of the noise such an airplane would generate would come from the nozzle, where a hot, high-speed jet exits the engine. Several different nozzle configurations were used to produce nozzle systems with different acoustical and aerodynamic characteristics. The acoustical properties were measured by an array of microphones in an anechoic chamber, and the aerodynamics were measured by traditional pressure and temperature instruments as well as by Laser Doppler Velocimetry (LDV), a technique for visualizing the airflow pattern without disturbing it. These measurements were put together and compared for different configurations to examine the relationships between mixing and noise generation. The mixer-ejector nozzle with the installed flow-visualization windows (foreground), the optical equipment and the supporting structure for the Laser Doppler Velocimetry flow visualization (midfield), and the sound-absorbing wedges used to create an anechoic environment for acoustic testing (background) is shown. The High Speed Research Program is a NASA-funded effort, in cooperation with the U.S. aerospace industry, to develop enabling technologies for a future supersonic airliner. One of the technological barriers being addressed is noise generated during near-airport operation. The mixer-ejector nozzle concept is being examined as a way to reduce jet noise while maintaining thrust. Ambient air is mixed with the high-velocity engine exhaust to reduce the jet velocity and hence the noise generated by the jet. The model was designed and built by Pratt & Whitney under NASA contract. The test, completed in June 1995, was conducted in Lewis' Aero-Acoustic Propulsion Laboratory.

Visualization of grid-generated turbulence in He II using PTV

NASA Astrophysics Data System (ADS)

Mastracci, B.; Guo, W.

2017-12-01

Due to its low viscosity, cryogenic He II has potential use for simulating large-scale, high Reynolds number turbulent flow in a compact and efficient apparatus. To realize this potential, the behavior of the fluid in the simplest cases, such as turbulence generated by flow past a mesh grid, must be well understood. We have designed, constructed, and commissioned an apparatus to visualize the evolution of turbulence in the wake of a mesh grid towed through He II. Visualization is accomplished using the particle tracking velocimetry (PTV) technique, where μm-sized tracer particles are introduced to the flow, illuminated with a planar laser sheet, and recorded by a scientific imaging camera; the particles move with the fluid, and tracking their motion with a computer algorithm results in a complete map of the turbulent velocity field in the imaging region. In our experiment, this region is inside a carefully designed He II filled cast acrylic channel measuring approximately 16 × 16 × 330 mm. One of three different grids, which have mesh numbers M = 3, 3.75, or 5 mm, can be attached to the pulling system which moves it through the channel with constant velocity up to 600 mm/s. The consequent motion of the solidified deuterium tracer particles is used to investigate the energy statistics, effective kinematic viscosity, and quantized vortex dynamics in turbulent He II.

D GIS for Flood Modelling in River Valleys

NASA Astrophysics Data System (ADS)

Tymkow, P.; Karpina, M.; Borkowski, A.

2016-06-01

The objective of this study is implementation of system architecture for collecting and analysing data as well as visualizing results for hydrodynamic modelling of flood flows in river valleys using remote sensing methods, tree-dimensional geometry of spatial objects and GPU multithread processing. The proposed solution includes: spatial data acquisition segment, data processing and transformation, mathematical modelling of flow phenomena and results visualization. Data acquisition segment was based on aerial laser scanning supplemented by images in visible range. Vector data creation was based on automatic and semiautomatic algorithms of DTM and 3D spatial features modelling. Algorithms for buildings and vegetation geometry modelling were proposed or adopted from literature. The implementation of the framework was designed as modular software using open specifications and partially reusing open source projects. The database structure for gathering and sharing vector data, including flood modelling results, was created using PostgreSQL. For the internal structure of feature classes of spatial objects in a database, the CityGML standard was used. For the hydrodynamic modelling the solutions of Navier-Stokes equations in two-dimensional version was implemented. Visualization of geospatial data and flow model results was transferred to the client side application. This gave the independence from server hardware platform. A real-world case in Poland, which is a part of Widawa River valley near Wroclaw city, was selected to demonstrate the applicability of proposed system.

Experimental Study of the Structure of a Wingtip Vortex

NASA Technical Reports Server (NTRS)

Anderson, Elgin A.; Wright, Christopher T.

2000-01-01

A complete look at the near-field development and subsequent role-up of a wingtip vortex from a NACA 0015 wing section is investigated. Two separate but equally important surveys of the vortex structure in the region adjacent to the wingtip and approximately one chord length downstream of the trailing edge are performed. The two surveys provide qualitative flow-visualization an quantitative velocity measurement data. The near-field development and subsequent role-up of the vortex structures is strongly influenced by the angle-of-attack and the end-cap treatment of the wing section. The velocity field near the wingtip of the NACA 0015 wing section was measured with a triple-sensor hot wire probe and compared to flow visualization images produced with titanium tetrachloride smoke injection and laser illumination. The flat end-cap results indicate the formation of multiple, relatively strong vortex structures as opposed to the formation of a single vortex produced with the round end-cap. The multiple vortices generated by the flat end-cap are seen to rotate around a common ce te in a helical pattern until they eventually merge into a single vortex. Compared to a non-dimensional loading parameter, the results of the velocity and flow visualization data shows a "jetlike" axial velocity profile for loading parameter values on the order of 0.1 and a "wakelike" profile for much lower loading parameter values.

Advances in active control and optimization in turbulence

NASA Astrophysics Data System (ADS)

Freeman, Aaron Paul

The main objective of this research is to explore the effectiveness of pulsed plasma actuators for turbulence control. In particular, a pulsed plasma actuator is used in this research to implement active control, in the form of a localized body force, over turbulent separated shear layers. Applications of tins research include controlling the formation and distribution of large scale turbulent structures and optimizing turbulence-aberrated laser propagation. This research is primarily experimental, with the motivation for the work derived from theoretical analysis of a turbulent shear layer. The experimental work is considered within two primary flow regimes, compressible and incompressible. For both cases, a turbulent shear layer is generated and then forced with plasma which is introduced periodically at frequencies ranging between 1.0 kHz and 25.0 kHz. The Reynolds numbers, based on visual thickness, of the compressible and incompressible flows investigated in this research are 6.0 106 and 8.0 104 respectively. Experimental results for the compressible case, based on Shack-Hartmann profiling of turbulence-aberrated laser wavefronts, for laser propagation through forced and unforced shear flows show reductions in the laser aberrations of up to 27.5% with a pulsing frequency of 5.0 kHz as well as increases of up to 16.9% with a pulsing frequency of 1.0 kHz. Other pulsing frequencies within the specified range were experimental analyzed and found to exhibit little or no significant change in the laser aberrations compared to the unforced case. The direct results from the Shack-Hartmann wavefront sensor are used to calculate the power spectra of the recorded Optical Path Difference profiles to verify the correlation between large aero-optical aberrations and propagation through large turbulent structures. Shadowgraph imaging of the compressible flow field was conducted to visually demonstrate the same. The experimental procedure for the incompressible shear layer involves imaging the flow field using fog-Mie scattering. The analysis for the resulting incompressible shear layer images include investigations of the distribution of large scale structures and the associated effects that periodic forcing has on the shear layer relating to mixing enhancement and scalar geometry. The effects of periodic forcing on mixing will be determined based on the scalar probability density function and the scalar power spectrum. In addition, the geometry of the scalar interfaces will be examined in terms of the generalized fractal dimension to determine the effects that periodic forcing has on the scale dependency of self-similarity within the flow field. Results from the experiments for the incompressible shear layer show that mixing can be increased by up to 8.4% as determined based on increases within the intermediate scalar probability density function and decreased by as much as 30.8% at forcing frequencies of 25.0 kHz and 1.0 kHz respectively. Additionally, this research shows that the extent of the range of scales of geometrical self-similarity of iso-concentration interfaces extracted from the flow images can be increased by up to 75.0% or reduced by as much as 75.0% depending on the forcing frequency applied. These results show that aero-optical interactions in a compressible shear layer as well as both mixing and the interfacial geometry in incompressible shear layers can be substantially modified by the periodic forcing.

Application of holography to flow visualization within rotating compressor blade row. [to determine three dimensional shock patterns

NASA Technical Reports Server (NTRS)

Wuerker, R. F.; Kobayashi, R. J.; Heflinger, L. O.; Ware, T. C.

1974-01-01

Two holographic interblade row flow visualization systems were designed to determine the three-dimensional shock patterns and velocity distributions within the rotating blade row of a transonic fan rotor, utilizing the techniques of pulsed laser transmission holography. Both single- and double-exposure bright field holograms and dark field scattered-light holograms were successfully recorded. Two plastic windows were installed in the rotor tip casing and outer casing forward of the rotor to view the rotor blade passage. The viewing angle allowed detailed investigation of the leading edge shocks and shocks in the midspan damper area; limited details of the trailing edge shocks also were visible. A technique was devised for interpreting the reconstructed holograms by constructing three dimensional models that allowed identification of the major shock systems. The models compared favorably with theoretical predictions and results of the overall and blade element data. Most of the holograms were made using the rapid double-pulse technique.

Holographic aids for internal combustion engine flow studies

NASA Technical Reports Server (NTRS)

Regan, C.

1984-01-01

Worldwide interest in improving the fuel efficiency of internal combustion (I.C.) engines has sparked research efforts designed to learn more about the flow processes of these engines. The flow fields must be understood prior to fuel injection in order to design efficient valves, piston geometries, and fuel injectors. Knowledge of the flow field is also necessary to determine the heat transfer to combustion chamber surfaces. Computational codes can predict velocity and turbulence patterns, but experimental verification is mandatory to justify their basic assumptions. Due to their nonintrusive nature, optical methods are ideally suited to provide the necessary velocity verification data. Optical sytems such as Schlieren photography, laser velocimetry, and illuminated particle visualization are used in I.C. engines, and now their versatility is improved by employing holography. These holographically enhanced optical techniques are described with emphasis on their applications in I.C. engines.

Diagnostic blood-flow monitoring during therapeutic interventions using color Doppler optical coherence tomography

NASA Astrophysics Data System (ADS)

Yazdanfar, Siavash; Kulkarni, Manish D.; Wong, Richard C. K.; Sivak, Michael J., Jr.; Willis, Joseph; Barton, Jennifer K.; Welch, Ashley J.; Izatt, Joseph A.

1998-04-01

A recently developed modality for blood flow measurement holds high promise in the management of bleeding ulcers. Color Doppler optical coherence tomography (CDOCT) uses low- coherence interferometry and digital signal processing to obtain precise localization of tissue microstructure simultaneous with bi-directional quantitation of blood flow. We discuss CDOCT as a diagnostic tool in the management of bleeding gastrointestinal lesions. Common treatments for bleeding ulcers include local injection of a vasoconstrictor, coagulation of blood via thermal contact or laser treatment, and necrosis of surrounding tissue with a sclerosant. We implemented these procedures in a rat dorsal skin flap model, and acquired CDOCT images before and after treatment. In these studies, CDOCT succeeded in identifying cessation of flow before it could be determined visually. Hence, we demonstrate the diagnostic capabilities of CDOCT in the regulation of bleeding in micron-scale vessels.

Laser heating of aqueous samples on a micro-optical-electro-mechanical system

DOEpatents

Beer, Neil Reginald; Kennedy, Ian

2013-12-17

A system of heating a sample on a microchip includes the steps of providing a microchannel flow channel in the microchip; positioning the sample within the microchannel flow channel, providing a laser that directs a laser beam onto the sample for heating the sample; providing the microchannel flow channel with a wall section that receives the laser beam and enables the laser beam to pass through wall section of the microchannel flow channel without being appreciably heated by the laser beam; and providing a carrier fluid in the microchannel flow channel that moves the sample in the microchannel flow channel wherein the carrier fluid is not appreciably heated by the laser beam.

Laser heating of aqueous samples on a micro-optical-electro-mechanical system

DOEpatents

Beer, Neil Reginald; Kennedy, Ian

2013-02-05

A system of heating a sample on a microchip includes the steps of providing a microchannel flow channel in the microchip; positioning the sample within the microchannel flow channel, providing a laser that directs a laser beam onto the sample for heating the sample; providing the microchannel flow channel with a wall section that receives the laser beam and enables the laser beam to pass through wall section of the microchannel flow channel without being appreciably heated by the laser beam; and providing a carrier fluid in the microchannel flow channel that moves the sample in the microchannel flow channel wherein the carrier fluid is not appreciably heated by the laser beam.

Aperiodic pressure pulsation under non optimal hydraulic turbine regimes at low swirl number

NASA Astrophysics Data System (ADS)

Skripkin, S. G.; Tsoy, M. A.; Kuibin, P. A.; Shtork, S. I.

2017-09-01

Off-design operating conditions of hydraulic turbines is hindered by pressure fluctuations in the draft tube of the turbine. A precessing helical vortex rope develops, which imperils the mechanical structure and limits the operation flexibility of hydropower station. Understanding of the underlying instabilities of precessing vortex rope at low swirl number is incomplete. In this paper flow regimes with different residual swirl is analysed, particular attention is paid to the regime with a small swirl parameter. Study defines upper and low boundaries of regime where aperiodic pressure surge is observed. Flow field at the runner exit is investigated by Laser Doppler Velocimetry and high-speed visualizations, which are complemented draft tube wall pressure measurements.

Fringe localization requirements for three-dimensional flow visualization of shock waves in diffuse-illumination double-pulse holographic interferometry

NASA Technical Reports Server (NTRS)

Decker, A. J.

1982-01-01

A theory of fringe localization in rapid-double-exposure, diffuse-illumination holographic interferometry was developed. The theory was then applied to compare holographic measurements with laser anemometer measurements of shock locations in a transonic axial-flow compressor rotor. The computed fringe localization error was found to agree well with the measured localization error. It is shown how the view orientation and the curvature and positional variation of the strength of a shock wave are used to determine the localization error and to minimize it. In particular, it is suggested that the view direction not deviate from tangency at the shock surface by more than 30 degrees.

Experimental exploration of underexpanded supersonic jets

NASA Astrophysics Data System (ADS)

André, Benoît; Castelain, Thomas; Bailly, Christophe

2014-01-01

Two underexpanded free jets at fully expanded Mach numbers = 1.15 and 1.50 are studied. Schlieren visualizations as well as measurements of static pressure, Pitot pressure and velocity are performed. All these experimental techniques are associated to obtain an accurate picture of the jet flow development. In particular, expansion, compression and neutral zones have been identified in each shock cell. Particle lag is considered by integrating the equation of motion for particles in a fluid flow and it is found that the laser Doppler velocimetry is suitable for investigating shock-containing jets. Even downstream of the normal shock arising in the = 1.50 jet, the measured gradual velocity decrease is shown to be relevant.

Interferometric and schlieren characterization of the plasmas and shock wave dynamics during laser-triggered discharge in atmospheric air

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wei, Wenfu; Li, Xingwen, E-mail: xwli@mail.xjtu.edu.cn; Wu, Jian

2014-08-15

This paper describes our efforts to reveal the underlying physics of laser-triggered discharges in atmospheric air using a Mach-Zehnder interferometer and schlieren photography. Unlike the hemispherical shock waves that are produced by laser ablation, bell-like morphologies are observed during laser-triggered discharges. Phase shifts are recovered from the interferograms at a time of 1000 ns by the 2D fast Fourier transform method, and then the values of the refractive index are deduced using the Abel inversion. An abundance of free electrons is expected near the cathode surface. The schlieren photographs visualize the formation of stagnation layers at ∼600 ns in the interaction zonesmore » of the laser- and discharge-produced plasmas. Multiple reflected waves are observed at later times with the development of shock wave propagations. Estimations using the Taylor-Sedov self-similar solution indicated that approximately 45.8% and 51.9% of the laser and electrical energies are transferred into the gas flow motions, respectively. Finally, numerical simulations were performed, which successfully reproduced the main features of the experimental observations, and provided valuable insights into the plasma and shock wave dynamics during the laser-triggered discharge.« less

Control of Interacting Vortex Flows at Subsonic and Transonic Speeds Using Passive Porosity

NASA Technical Reports Server (NTRS)

Erickson, Gary E.

2003-01-01

A wind tunnel experiment was conducted in the NASA Langley Research Center (LaRC) 8-foot Transonic Pressure Tunnel (TPT) to determine the effects of passive surface porosity on vortex flow interactions about a general research fighter configuration at subsonic and transonic speeds. Flow- through porosity was applied to a wind leading-edge extension (LEX) mounted to a 65 deg cropped delta wind model to promote large nose-down pitching moment increments at high angles of attack. Porosity decreased the vorticity shed from the LEX, which weakened the LEX vortex and altered the global interactions of the LEX and wing vortices at high angles of attack. Six-component forces and moments and wing upper surface static pressure distributions were obtained at free- stream Mach numbers of 0.50, 0.85, and 1.20, Reynolds number of 2.5(10(exp-6) per foot, angles of attack up to 30 deg and angles of sideslip to plus or minus 8 deg. The off-surface flow field was visualized in selected cross-planes using a laser vapor screen flow visualization technique. Test data were obtained with a centerline vertical tail and with alternate twin, wing-mounted vertical fins having 0 deg and 30 deg cant angles. In addition, the porosity of the LEX was compartmentalized to determine the sensitivity of the vortex- dominated aerodynamics to the location and level of porosity applied to the LEX.

Control of Interacting Vortex Flows at Subsonic and Transonic Speeds Using Passive Porosity

NASA Technical Reports Server (NTRS)

Erickson, Gary E.

2003-01-01

A wind tunnel experiment was conducted in the NASA Langley Research Center (LaRC) 8-Foot Transonic Pressure Tunnel (TPT) to determine the effects of passive surface porosity on vortex flow interactions about a general research fighter configuration at subsonic and transonic speeds. Flow-through porosity was applied to a wing leading-edge extension (LEX) mounted to a 65 deg cropped delta wing model to promote large nose-down pitching moment increments at high angles of attack. Porosity decreased the vorticity shed from the LEX, which weakened the LEX vortex and altered the global interactions of the LEX and wing vortices at high angles of attack. Six-component forces and moments and wing upper surface static pressure distributions were obtained at free-stream Mach numbers of 0.50, 0.85, and 1.20, Reynolds number of 2.5(10(exp 6)) per foot, angles of attack up to 30 deg, and angles of sideslip to +/- 8 deg. The off-surface flow field was visualized in selected cross-planes using a laser vapor screen flow visualization technique. Test data were obtained with a centerline vertical tail and with alternate twin, wing-mounted vertical fins having 0 deg and 30 deg cant angles. In addition, the porosity of the LEX was compartmentalized to determine the sensitivity of the vortex-dominated aerodynamics to the location and level of porosity applied to the LEX.

Laser Doppler velocimetry for continuous flow solar-pumped iodine laser system

NASA Technical Reports Server (NTRS)

Tabibi, Bagher M.; Lee, Ja H.

1991-01-01

A laser Doppler velocimetry (LDV) system was employed to measure the flow velocity profile of iodide vapor inside laser tubes of 36 mm ID and 20 mm ID. The LDV, which was operated in the forward scatter mode used a low power (15 mW) He-Ne laser beam. Velocity ranges from 1 m/s was measured to within one percent accuracy. The flow velocity profile across the laser tube was measured and the intensity of turbulence was determined. The flow of iodide inside the laser tube demonstrated a mixture of both turbulence and laminar flow. The flowmeter used for the laser system previously was calibrated with the LDV and found to be in good agreement.

Flow speed of the ablation vapors generated during laser drilling of CFRP with a continuous-wave laser beam

NASA Astrophysics Data System (ADS)

Faas, S.; Freitag, C.; Boley, S.; Berger, P.; Weber, R.; Graf, T.

2017-03-01

The hot plume of ablation products generated during the laser drilling process of carbon fiber reinforced plastics (CFRP) with a continuous-wave laser beam was analyzed by means of high-speed imaging. The formation of compression shocks was observed within the flow of the evaporated material, which is an indication of flow speeds well above the local speed of sound. The flow speed of the hot ablation products can be estimated by analyzing the position of these compression shocks. We investigated the temporal evolution of the flow speed during the drilling process and the influence of the average laser power on the flow speed. The flow speed increases with increasing average laser powers. The moment of drilling through the material changes the conditions for the drilling process and was confirmed to influence the flow speed of the ablated material. Compression shocks can also be observed during laser cutting of CFRP with a moving laser beam.

Macular Structures, Optical Components, and Visual Acuity in Preschool Children after Intravitreal Bevacizumab or Laser Treatment.

PubMed

Lee, Yung-Sung; See, Lai-Chu; Chang, Shu-Hao; Wang, Nan-Kai; Hwang, Yih-Shiou; Lai, Chi-Chun; Chen, Kuan-Jen; Wu, Wei-Chi

2018-05-10

To investigate the macular structures, optical components, and visual acuity in preschool-aged children with a history of type I retinopathy of prematurity who underwent either intravitreal bevacizumab (IVB), laser, or a combination of treatments. Comparative interventional case series. A referred medical center in Taiwan. 80 eyes from 42 patients (33 IVB-treated eyes from 17 children, 24 laser-treated eyes from 13 children, and 23 laser + IVB-treated eyes from 12 children). Spectral-domain optical coherence tomography. The retinal thickness in the foveal area and the associated morphologic changes in foveal depression. Compared with the laser-treated and laser + IVB-treated eyes, the IVB-treated eyes had less myopia and deeper anterior chamber depths but presented similar axial lengths and corneal curvatures (P = .001, .002, .95 and .16, respectively). The IVB-treated eyes had significantly thinner foveal, parafoveal, and perifoveal retinal thicknesses (P < .01 for all) and a higher incidence of foveal depression than the laser- or laser + IVB-treated eyes. The macular and subfoveal choroidal thicknesses did not differ among the groups (P = .21 and .63, respectively). Moreover, compared with the eyes treated with laser or laser + IVB, the IVB-treated eyes had better uncorrected visual acuity, although a significant difference was not observed in best-corrected visual acuity (P = .008 and .29, respectively). Compared with laser therapy, IVB-treated eyes were associated with deeper anterior chamber depths and thinner foveal, parafoveal and perifoveal thicknesses. Moreover, these IVB-treated eyes had less refractive errors and better uncorrected visual acuity. Copyright © 2018. Published by Elsevier Inc.

Aerodynamics and performance verifications of test methods for laboratory fume cupboards.

PubMed

Tseng, Li-Ching; Huang, Rong Fung; Chen, Chih-Chieh; Chang, Cheng-Ping

2007-03-01

The laser-light-sheet-assisted smoke flow visualization technique is performed on a full-size, transparent, commercial grade chemical fume cupboard to diagnose the flow characteristics and to verify the validity of several current containment test methods. The visualized flow patterns identify the recirculation areas that would inevitably exist in the conventional fume cupboards because of the fundamental configurations and structures. The large-scale vortex structures exist around the side walls, the doorsill of the cupboard and in the vicinity of the near-wake region of the manikin. The identified recirculation areas are taken as the 'dangerous' regions where the risk of turbulent dispersion of contaminants may be high. Several existing tracer gas containment test methods (BS 7258:1994, prEN 14175-3:2003 and ANSI/ASHRAE 110:1995) are conducted to verify the effectiveness of these methods in detecting the contaminant leakage. By comparing the results of the flow visualization and the tracer gas tests, it is found that the local recirculation regions are more prone to contaminant leakage because of the complex interaction between the shear layers and the smoke movement through the mechanism of turbulent dispersion. From the point of view of aerodynamics, the present study verifies that the methodology of the prEN 14175-3:2003 protocol can produce more reliable and consistent results because it is based on the region-by-region measurement and encompasses the most area of the entire recirculation zone of the cupboard. A modified test method combined with the region-by-region approach at the presence of the manikin shows substantially different results of the containment. A better performance test method which can describe an operator's exposure and the correlation between flow characteristics and the contaminant leakage properties is therefore suggested.

Visualization of laser tattoo removal treatment effects in a mouse model by two-photon microscopy

PubMed Central

Jang, Won Hyuk; Yoon, Yeoreum; Kim, Wonjoong; Kwon, Soonjae; Lee, Seunghun; Song, Duke; Choi, Jong Woon; Kim, Ki Hean

2017-01-01

Laser tattoo removal is an effective method of eliminating tattoo particles in the skin. However, laser treatment cannot always remove the unwanted tattoo completely, and there are risks of either temporary or permanent side effects. Studies using preclinical animal models could provide detailed information on the effects of laser treatment in the skin, and might help to minimize side effects in clinical practices. In this study, two-photon microscopy (TPM) was used to visualize the laser treatment effects on tattoo particles in both phantom specimens and in vivo mouse models. Fluorescent tattoo ink was used for particle visualization by TPM, and nanosecond (ns) and picosecond (ps) lasers at 532 nm were used for treatment. In phantom specimens, TPM characterized the fragmentation of individual tattoo particles by tracking them before and after the laser treatment. These changes were confirmed by field emission scanning electron microscopy (FE-SEM). TPM was used to measure the treatment efficiency of the two lasers at different laser fluences. In the mouse model, TPM visualized clusters of tattoo particles in the skin and detected their fragmentation after the laser treatment. Longitudinal TPM imaging observed the migration of cells containing tattoo particles after the laser treatment. These results show that TPM may be useful for the assessment of laser tattoo removal treatment in preclinical studies. PMID:28856046

Vortex shedding in bileaflet heart valve prostheses.

PubMed

Gross, J M; Shermer, C D; Hwang, N H

1988-01-01

A dynamic study of two geometrically similar bileaflet heart valve prostheses (HVP) was performed using a physiologic mock circulatory flow loop. The HVPs studied were the 25 mm St. Jude Medical (SJM) and the 25 mm Carbomedics (CMI) in the aortic position and the 27 mm SJM and 27 mm CMI in the mitral position. All data were collected at a heart rate of 70 beats/min and a cardiac output of 5.0 L/min. Flow visualization was conducted in the transparent flow chambers of the pulsatile mock circulatory flow loop using a 15 mW He-Ne laser light source. A cylindrical lens and optics system converted the incident laser beam into a thin parallel light plane, and 420 microns tracer particles were suspended in the testing fluid to illuminate the flow field at selected planes. Frame-by-frame analysis of the 16 mm high-speed cine provides detailed phasic flow patterns in the vicinity of the HVP. A series of still photographs of flow patterns, taken at approximately 22.5 degrees phase intervals, are sequentially presented for each HVP. In the aortic position, a Karman-like vortex pattern appears downstream of the SJM at the end of the ejection phase. The CMI exhibits a rather symmetrical ejection flow pattern that turns into random motion immediately after the onset of ejection. In the mitral position, the SJM again exhibits a strong core flow during ventricular filling, whereas the CMI produces a more diffuse pattern during the same period. A pair of vortices shed from both the SJM and CMI are clearly visible toward the end of the ventricular filling phase. The vortex mechanisms are discussed in light of leaflet boundary layer formation.

Laser heating of aqueous samples on a micro-optical-electro-mechanical system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Beer, Neil Reginald; Kennedy, Ian

2013-12-17

A system of heating a sample on a microchip includes the steps of providing a microchannel flow channel in the microchip; positioning the sample within the microchannel flow channel, providing a laser that directs a laser beam onto the sample for heating the sample; providing the microchannel flow channel with a wall section that receives the laser beam and enables the laser beam to pass through wall section of the microchannel flow channel without being appreciably heated by the laser beam; and providing a carrier fluid in the microchannel flow channel that moves the sample in the microchannel flow channelmore » wherein the carrier fluid is not appreciably heated by the laser beam.« less

Laser-Excited Luminescent Tracers for Planar Concentration Measurements in Gaseous Jets

NASA Astrophysics Data System (ADS)

Lozano, Antonio

Tracers currently used in planar laser-induced fluorescence concentration measurements are not ideal for some experimental conditions, e.g., non-reacting turbulent gaseous flows at standard temperature and pressure. In this work, a number of chemicals have been evaluated, through consideration of their physical and photophysical properties, for use as luminescent concentration markers in turbulent gaseous flows. Two selected substances, biacetyl and acetone, have been studied in more detail. Acetone PLIF concentration images have been acquired in a non-reacting air jet, and the results have been compared to similar images obtained seeding with biacetyl. Acetone has proven to be a superior tracer when imaging fluorescence emission. Acetone has also been used as a fuel marker in hydrogen and methane diffusion flames. This single -laser technique enables simultaneous recording of the acetone and OH fluorescence emissions, as well as Mie scattering from ambient air dust particles. Acetone-sensitized, collisionally-induced biacetyl phosphorescence has been used to visualize molecular mixing in gaseous flows. Initial attempts to produce quantitative results with this method through simultaneous imaging of acetone fluorescence and collisionally-induced biacetyl emission, are described. Using laser-induced biacetyl phosphorescence imaging, a data set of cross-cut concentration images has been acquired in a nitrogen coflowing jet (Re = 5,000). The images have been statistically analyzed. Very simple models of the instantaneous concentration profile have been compared to the experimental data. Of all the tested models, a paraboloid has resulted to be the best approximation to the instantaneous 2-D profile. Finally, an experiment to study jet mixing in crossflow using acetone PLIF imaging has been designed. The flow facility has been constructed, and preliminary images obtained with a high quantum efficiency, thinned CCD detector have revealed the presence of jet structures inside the wake region that appear to be dependent on the jet/crossflow velocity ratio.

Experimental Study of Structure of Low Density Jet Impinging on Tilt Plate by LIF and PSP

NASA Astrophysics Data System (ADS)

Fujimoto, Tetsuo; Sato, Kimihiko; Naniwa, Shuji; Inoue, Tomoyuki; Nakashima, Kouji

2000-07-01

The structure of low density jets impinging on a tilt plate is studied by hybrid use of LIF and PSP. The jet through an orifice flows into low pressure chamber of 0.12 Torr and impinges on to the tilt plate with angle from jet axis 45 or 60 or 90. A horizontal plane including the jet axis is visualized by LIF of seeded Iodine molecule, scanning a laser beam along the jet axis. On the other hand, the pressure distribution on the tilt plate is visualized by PSP. In comparing the results of the two methods, the shock wave system is analyzed. Deformation of the Mach disk and the barrel shock are confirmed.

Near infrared lasers in flow cytometry.

PubMed

Telford, William G

2015-07-01

Technology development in flow cytometry has closely tracked laser technology, the light source that flow cytometers almost exclusively use to excite fluorescent probes. The original flow cytometers from the 1970s and 1980s used large water-cooled lasers to produce only one or two laser lines at a time. Modern cytometers can take advantage of the revolution in solid state laser technology to use almost any laser wavelength ranging from the ultraviolet to the near infrared. Commercial cytometers can now be equipped with many small solid state lasers, providing almost any wavelength needed for cellular analysis. Flow cytometers are now equipped to analyze 20 or more fluorescent probes simultaneously, requiring multiple laser wavelengths. Instrument developers are now trying to increase this number by designing fluorescent probes that can be excited by laser wavelength at the "edges" of the visible light range, in the near ultraviolet and near-infrared region. A variety of fluorescent probes have been developed that excite with violet and long wavelength ultraviolet light; however, the near-infrared range (660-800 nm) has yet seen only exploitation in flow cytometry. Fortunately, near-infrared laser diodes and other solid state laser technologies appropriate for flow cytometry have been in existence for some time, and can be readily incorporated into flow cytometers to accelerate fluorescent probe development. The near infrared region represents one of the last "frontiers" to maximize the number of fluorescent probes that can be analyzed by flow cytometry. In addition, near infrared fluorescent probes used in biomedical tracking and imaging could also be employed for flow cytometry with the correct laser wavelengths. This review describes the available technology, including lasers, fluorescent probes and detector technology optimal for near infrared signal detection. Published by Elsevier Inc.

Flowfield measurements in a separated and reattached flat plate turbulent boundary layer

NASA Technical Reports Server (NTRS)

Patrick, William P.

1987-01-01

The separation and reattachment of a large-scale, two-dimensional turbulent boundary layer at low subsonic speed on a flat plate has been studied experimentally. The separation bubble was 55 cm long and had a maximum bubble thickness, measured to the height of the mean dividing streamline, of 17 cm, which was twice the thickness of the inlet boundary layer. A combination of laser velocimetry, hot-wire anemometry, pneumatic probing techniques, and flow visualization were used as diagnostics. Principal findings were that an outer inviscid rotational flow was defined which essentially convected over the blockage associated with the inner, viscously dominated bubble recirculation region. A strong backflow region in which the flow moved upstream 100 percent of the time was measured near the test surface over the central 35 percent of the bubble. A laminar backflow boundary layer having pseudo-turbulent characteristics including a log-linear velocity profile was generated under the highly turbulent backflow. Velocity profile shapes in the reversed flow region matched a previously developed universal backflow profile at the upstream edge of the separation region but not in the steady backflow region downstream. A smoke flow visualization movie and hot-film measurements revealed low frequency nonperiodic flapping at reattachment. However, forward flow fraction data at reattachment and mean velocity profiles in the redeveloping boundary layer downstream of reattachment correlated with backward-facing step data when the axial dimension was scaled by the distance from the maximum bubble thickness to reattachment.

Active control of Boundary Layer Separation & Flow Distortion in Adverse Pressure Gradient Flows via Supersonic Microjets

NASA Technical Reports Server (NTRS)

Alvi, Farrukh S.; Gorton, Susan (Technical Monitor)

2005-01-01

Inlets to aircraft propulsion systems must supply flow to the compressor with minimal pressure loss, flow distortion or unsteadiness. Flow separation in internal flows such as inlets and ducts in aircraft propulsion systems and external flows such as over aircraft wings, is undesirable as it reduces the overall system performance. The aim of this research has been to understand the nature of separation and more importantly, to explore techniques to actively control this flow separation. In particular, the use of supersonic microjets as a means of controlling boundary layer separation was explored. The geometry used for the early part of this study was a simple diverging Stratford ramp, equipped with arrays of supersonic microjets. Initial results, based on the mean surface pressure distribution, surface flow visualization and Planar Laser Scattering (PLS) indicated a reverse flow region. We implemented supersonic microjets to control this separation and flow visualization results appeared to suggest that microjets have a favorable effect, at least to a certain extent. However, the details of the separated flow field were difficult to determine based on surface pressure distribution, surface flow patterns and PLS alone. It was also difficult to clearly determine the exact influence of the supersonic microjets on this flow. In the latter part of this study, the properties of this flow-field and the effect of supersonic microjets on its behavior were investigated in further detail using 2-component (planar) Particle Image Velocimetry (PIV). The results clearly show that the activation of microjets eliminated flow separation and resulted in a significant increase in the momentum of the fluid near the ramp surface. Also notable is the fact that the gain in momentum due to the elimination of flow separation is at least an order of magnitude larger (two orders of magnitude larger in most cases) than the momentum injected by the microjets and is accomplished with very little mass flow through the microjets.

Multiple Near Wake Patterns Behind Annular Rings

NASA Astrophysics Data System (ADS)

Zhang, Jinzhong; Higuchi, Hiroshi; Muzas, Brian K.; Furuya, Shojiro

1996-11-01

Wake interactions behind concentric annular rings at different spacing ratios were experimentally investigated. The flow visualization, laser Doppler velocimetry data and results from the particle tracking velocimetry are presented and discussed. Jets through individual slots merged in multiply-stable, axisymmetric manners. Most flow patterns were persistent unless the flow was strongly disturbed. The vortex interactions from individual annular elements were also axisymmetric in the near wake. This is in contrast to the asymmetric flows observed earlier behind two-dimensional slotted plates (Higuchi et al. J. Aircraft 26 1989, Phys. Fluids 6(1), 1994). The intermediate wake, however, was dominated by large scale, three-dimensional wake motions even at moderate porosity. Onset of the specific flow patterns was associated with the interactions among start-up vortices. Given model geometry, different turbulent structures and mean velocity profiles were observed in the intermediate wake depending on the near wake pattern. *BKM was a NSF-REU Program undergrad. from Princeton U. and SF was from Mitsubishi Heavy Industries. This work was suppoted in part by the Naval Air Warfare Center.

Characterization of flow in a scroll duct

NASA Technical Reports Server (NTRS)

Begg, E. K.; Bennett, J. C.

1985-01-01

A quantitative, flow visualization study was made of a partially elliptic cross section, inward curving duct (scroll duct), with an axial outflow through a vaneless annular cutlet. The working fluid was water, with a Re(d) of 40,000 at the inlet to the scroll duct, this Reynolds number being representative of the conditions in an actual gas turbine scroll. Both still and high speed moving pictures of fluorescein dye injected into the flow and illuminated by an argon ion laser were used to document the flow. Strong secondary flow, similar to the secondary flow in a pipe bend, was found in the bottom half of the scroll within the first 180 degs of turning. The pressure field set up by the turning duct was strong enough to affect the inlet flow condition. At 90 degs downstream, the large scale secondary flow was found to be oscillatory in nature. The exit flow was nonuniform in the annular exit. By 270 degs downstream, the flow appeared unorganized with no distinctive secondary flow pattern. Large scale structures from the upstream core region appeared by 90 degs and continued through the duct to reenter at the inlet section.

Visualization of Flows in Packed Beds of Twisted Tapes

NASA Technical Reports Server (NTRS)

Hendricks, R. C.; Braun, M. J.; Peloso, D.; Athavale, M. M.; Mullen, R. L.

2002-01-01

A videotape presentation of the flow field in a packed bed of 48 twisted tapes which can be simulated by very thin virtual cylinders has been assembled. The indices of refraction of the oil and the Lucite twisted tapes were closely matched, and the flow was seeded with magnesium oxide particles. Planar laser light projected the flow field in two dimensions both along and transverse to the flow axis. The flow field was three dimensional and complex to describe, yet the most prominent finding was flow threads. It appeared that axial flow spiraled along either within the confines of a virtual cylindrical boundary or within the exterior region, between the tangency points, of the virtual cylinders. Random packing and bed voids created vortices and disrupted the laminar flow but minimized the entrance effects. The flow-pressure drops in the packed bed fell below the Ergun model for porous-media flows. Single-twisted-tape results of Smithberg and Landis (1964) were used to guide the analysis. In appendix A the results of several investigators are scaled to the Ergun model. Further investigations including different geometric configurations, computational fluid dynamic (CFD) gridding, and analysis are required.

Photophoretic velocimetry for the characterization of aerosols.

PubMed

Haisch, Christoph; Kykal, Carsten; Niessner, Reinhard

2008-03-01

Aerosols are particles in a size range from some nanometers to some micrometers suspended in air or other gases. Their relevance varies as wide as their origin and composition. In the earth's atmosphere they influence the global radiation balance and human health. Artificially produced aerosols are applied, e.g., for drug administration, as paint and print pigments, or in rubber tire production. In all these fields, an exact characterization of single particles as well as of the particle ensemble is essential. Beyond characterization, continuous separation is often required. State-of-the-art separation techniques are based on electrical, thermal, or flow fields. In this work we present an approach to apply light in the form of photophoretic (PP) forces for characterization and separation of aerosol particles according to their optical properties. Such separation technique would allow, e.g., the separation of organic from inorganic particles of the same aerodynamic size. We present a system which automatically records velocities induced by PP forces and does a statistical evaluation in order to characterize the particle ensemble properties. The experimental system essentially consists of a flow cell with rectangular cross section (1 cm(2), length 7 cm), where the aerosol stream is pumped through in the vertical direction at ambient pressure. In the cell, a laser beam is directed orthogonally to the particle flow direction, which results in a lateral displacement of the particles. In an alternative configuration, the beam is directed in the opposite direction to the aerosol flow; hence, the particles are slowed down by the PP force. In any case, the photophoretically induced variations of speed and position are visualized by a second laser illumination and a camera system, feeding a mathematical particle tracking algorithm. The light source inducing the PP force is a diode laser (lambda = 806 nm, P = 0.5 W).

Utilization of laser Doppler flowmetry and tissue spectrophotometry for burn depth assessment using a miniature swine model.

PubMed

Lotter, Oliver; Held, Manuel; Schiefer, Jennifer; Werner, Ole; Medved, Fabian; Schaller, Hans-Eberhard; Rahmanian-Schwarz, Afshin; Jaminet, Patrick; Rothenberger, Jens

2015-01-01

Currently, the diagnosis of burn depth is primarily based on a visual assessment and can be dependent on the surgeons' experience. The goal of this study was to determine the ability of laser Doppler flowmeter combined with a tissue spectrophotometer to discriminate burn depth in a miniature swine burn model. Burn injuries of varying depth, including superficial-partial, deep-partial, and full thickness, were created in seven Göttingen minipigs using an aluminium bar (100 °C), which was applied to the abdominal skin for periods of 1, 3, 6, 12, 30, and 60 seconds with gravity alone. The depth of injury was evaluated histologically using hematoxylin and eosin staining. All burns were assessed 3 hours after injury using a device that combines a laser light and a white light to determine blood flow, hemoglobin oxygenation, and relative amount of hemoglobin. The blood flow (41 vs. 124 arbitrary units [AU]) and relative amount of hemoglobin (32 vs. 52 AU) were significantly lower in full thickness compared with superficial-partial thickness burns. However, no significant differences in hemoglobin oxygenation were observed between these depths of burns (61 vs. 60%). These results show the ability of laser Doppler flowmeter and tissue spectrophotometer in combination to discriminate between various depths of injury in the minipig model, suggesting that this device may offer a valuable tool for burn depth assessment influencing burn management. © 2014 by the Wound Healing Society.

Wind Tunnel Investigation of the Effects of Surface Porosity and Vertical Tail Placement on Slender Wing Vortex Flow Aerodynamics at Supersonic Speeds

NASA Technical Reports Server (NTRS)

Erickson, Gary E.

2007-01-01

A wind tunnel experiment was conducted in the NASA Langley Research Center (LaRC) Unitary Plan Wind Tunnel (UPWT) to determine the effects of passive surface porosity and vertical tail placement on vortex flow development and interactions about a general research fighter configuration at supersonic speeds. Optical flow measurement and flow visualization techniques were used that featured pressure sensitive paint (PSP), laser vapor screen (LVS), and schlieren, These techniques were combined with conventional electronically-scanned pressure (ESP) and six-component force and moment measurements to quantify and to visualize the effects of flow-through porosity applied to a wing leading edge extension (LEX) and the placement of centerline and twin vertical tails on the vortex-dominated flow field of a 65 cropped delta wing model. Test results were obtained at free-stream Mach numbers of 1.6, 1.8, and 2.1 and a Reynolds number per foot of 2.0 million. LEX porosity promoted a wing vortex-dominated flow field as a result of a diffusion and weakening of the LEX vortex. The redistribution of the vortex-induced suction pressures contributed to large nose-down pitching moment increments but did not significantly affect the vortex-induced lift. The trends associated with LEX porosity were unaffected by vertical tail placement. The centerline tail configuration generally provided more stable rolling moments and yawing moments compared to the twin wing-mounted vertical tails. The strength of a complex system of shock waves between the twin tails was reduced by LEX porosity.

Effect of Chromoendoscopy Filters on Visualization of KTP Laser-Associated Tissue Changes: A Cadaveric Animal Model.

PubMed

Johnson, Christopher M; Pate, Mariah B; Postma, Gregory N

2018-04-01

Standard KTP laser (potassium titanyl phosphate) wavelength-specific protective eyewear often impairs visualization of tissue changes during laser treatment. This sometimes necessitates eyewear removal to evaluate tissue effects, which wastes time and poses safety concerns. The objective was to determine if "virtual" or "electronic" chromoendoscopy filters, as found on some endoscopy platforms, could alleviate the restricted visualization inherent to protective eyewear. A KTP laser was applied to porcine laryngeal tissue and recorded via video laryngoscopy with 1 optical (Olympus Narrow Band Imaging) and 8 digital (Pentax Medical I-scan) chromoendoscopy filters. Videos were viewed by 11 otolaryngologists wearing protective eyewear. Using a discrete visual analog scale, they rated each filter on its ability to improve visualization,. No filter impaired visualization; 5 of 9 improved visualization. Based on statistical significance, the number of positive responses, and the lack of negative responses, narrow band imaging and the I-scan tone enhancement filter for leukoplakia performed best. These filters could shorten procedure time and improve safety; therefore, further clinical evaluation is warranted.

Fluid mechanics of fusion lasers. Final report, September 11, 1978-June 5, 1980

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shwartz, J; Kulkarny, V A; Ausherman, D A

1980-01-01

Flow loop components required to operate continuous-flow, repetitively-pulsed CO/sub 2/ and KrF laser drivers for ICF were identified and their performance requirements were specified. It was found that the laser flow loops can have a major effect on the laser beam quality and overall efficiency. The pressure wave suppressor was identified as the most critical flow loop component. The performance of vented side-wall suppressors was evaluated both analytically and experimentally and found capable of meeting the performance requirements of the CO/sub 2/ and KrF fusion lasers. All other laser flow loop components are essentially similar to those used in conventional,more » low speed wind tunnels and are therefore well characterized and can be readily incorporated into fusion laser flow systems designs.« less

Small lasers in flow cytometry.

PubMed

Telford, William G

2004-01-01

Laser technology has made tremendous advances in recent years, particularly in the area of diode and diode-pumped solid state sources. Flow cytometry has been a direct beneficiary of these advances, as these small, low-maintenance, inexpensive lasers with reasonable power outputs are integrated into flow cytometers. In this chapter we review the contribution and potential of solid-state lasers to flow cytometry, and show several examples of these novel sources integrated into production flow cytometers. Technical details and critical parameters for successful application of these lasers for biomedical analysis are reviewed.

[Grid laser photocoagulation in diffuse diabetic macular edema].

PubMed

Degenring, Robert F; Hugger, Philipp; Sauder, Gangolf; Jonas, Jost B

2004-01-01

To evaluate the clinical outcome of macular grid laser photocoagulation in the treatment of diffuse diabetic macular oedema. The retrospective study included 30 consecutive patients (41 eyes) who were treated by macular argon green grid laser photocoagulation for diffuse diabetic macular oedema. Follow-up time was 31.4 +/- 19.6 weeks. Visual acuity decreased from 0.25 +/- 0.18 (range, 0.03 - 0.8) to 0.20 +/- 0.18 (range, 0.02 - 0.8) (P = 0.045), representing a change of - 0.9 +/- 2,32 lines. 5 (12.2 %) eyes gained in visual acuity, visual acuity remained unchanged for 23 (56.1 %) eyes, and 13 (31.7 %) eyes showed a visual loss of more than one line. In eyes with a baseline visual acuity > or = 0.2 (N = 24) visual acuity dropped from 0.36 +/- 0.15 (0.2 - 0.8; median 0.3) to 0.29 +/- 0.19 (0.05 - 0.8; median 0.2) (p = 0.038). 3 eyes (12.5 %) gained > or = 2 lines, 11 eyes (45.8 %) lost > or = 2 lines, 10 eyes (41.7 %) remained stable. Mean loss was - 1.63 +/- 2.53 lines. Eyes with a baseline visual acuity < or = 0.2 did not change significantly. In the present study mean visual acuity decreased in the whole population and especially in the subgroup with a baseline visual acuity of > or = 0.2 after macular grid laser photocoagulation for diffuse diabetic macular oedema. Mean visual loss was just below the predefined 2 lines. In view of these results and upcoming new pharmacological and surgical treatment modalities, the significance of grid laser photocoagulation should be re-discussed.

Experimental Investigation of Laser-sustained Plasma in Supersonic Argon Flow

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sperber, David; Eckel, Hans-Albert; Moessinger, Peter

Laser-induced energy deposition is widely discussed as a flow control technique in supersonic transportation. In case of thermal laser-plasma upstream of a blunt body, a substantial adaptation of shock wave geometry and magnitude of wave drag is predicted. Related to the research on laser supported detonation, the paper describes the implementation of laser-sustained plasma in a supersonic Argon jet. The stable plasma state is generated by the intersection of a Q-switched Nd:YAG-laser and a continuous wave CO{sub 2}-laser beams, for ignition and maintenance of the plasma respectively. A miniature supersonic Ludwieg tube test facility generates a supersonic jet at velocitiesmore » of Mach 2.1. Modifications of the flow and plasma conditions are investigated and characterized by Schlieren flow visualisation, laser energy transmission and plasma radiation measurements. The results include the discussions of the flow field as well as the required laser and gas parameters.« less

SUBTHRESHOLD MICROPULSE DIODE LASER VERSUS CONVENTIONAL LASER PHOTOCOAGULATION FOR DIABETIC MACULAR EDEMA: A Meta-Analysis of Randomized Controlled Trials.

PubMed

Chen, Guohai; Tzekov, Radouil; Li, Wensheng; Jiang, Fangzheng; Mao, Sihong; Tong, Yuhua

2016-11-01

To evaluate the relative efficacy of subthreshold micropulse diode laser versus conventional laser photocoagulation for the treatment of diabetic macular edema. A comprehensive literature search was conducted to find relevant randomized controlled trials (RCTs). Efficacy estimates were determined by comparing weighted mean differences of the mean change of best-corrected visual acuity and central macular thickness from baseline. Six RCTs were selected for this meta-analysis, including 398 eyes (203 eyes in the subthreshold micropulse diode laser group and 195 eyes in the conventional laser group). Subthreshold micropulse diode laser was superior to conventional laser in terms of mean change of logMAR best-corrected visual acuity at 3, 9, and 12 months after treatment (P = 0.02; P = 0.04, and P = 0.03, respectively), and it showed a similar trend at 6 months (P = 0.05). Although, there was no significant difference in terms of mean change in central macular thickness from baseline to 3, 6, 9, or 12 months (P = 0.80; P = 0.20; P = 0.88, and P = 0.86, respectively). Subthreshold micropulse diode laser treatment resulted in better visual acuity compared with conventional laser, although the differences before 12 months are likely to be too small to be of clinical relevance and may be dependent on baseline best-corrected visual acuity. The two types of treatment seem to have similar anatomical outcome.

Laser manipulation of atomic and molecular flows

NASA Astrophysics Data System (ADS)

Lilly, Taylor C.

The continuing advance of laser technology enables a range of broadly applicable, laser-based flow manipulation techniques. The characteristics of these laser-based flow manipulations suggest that they may augment, or be superior to, such traditional electro-mechanical methods as ionic flow control, shock tubes, and small scale wind tunnels. In this study, methodology was developed for investigating laser flow manipulation techniques, and testing their feasibility for a number of aerospace, basic physics, and micro technology applications. Theories for laser-atom and laser-molecule interactions have been under development since the advent of laser technology. The theories have yet to be adequately integrated into kinetic flow solvers. Realizing this integration would greatly enhance the scaling of laser-species interactions beyond the realm of ultra-cold atomic physics. This goal was realized in the present study. A representative numerical investigation, of laser-based neutral atomic and molecular flow manipulations, was conducted using near-resonant and non-resonant laser fields. To simulate the laser interactions over a range of laser and flow conditions, the following tools were employed: a custom collisionless gas particle trajectory code and a specifically modified version of the Direct Simulation Monte Carlo statistical kinetic solver known as SMILE. In addition to the numerical investigations, a validating experiment was conducted. The experimental results showed good agreement with the numerical simulations when experimental parameters, such as finite laser line width, were taken into account. Several areas of interest were addressed: laser induced neutral flow steering, collimation, direct flow acceleration, and neutral gas heating. Near-resonant continuous wave laser, and non-resonant pulsed laser, interactions with cesium and nitrogen were simulated. These simulations showed trends and some limitations associated with these interactions, used for flow steering and collimation. The use of one of these interactions, the induced dipole force, was extended beyond a single Gaussian laser field. The interference patterns associated with counter-propagating laser fields, or "optical lattices," were shown to be capable of both direct species acceleration and gas heating. This study resulted in predictions for a continuous, resonant laser-cesium flow with accelerations of 106 m/s2. For this circumstance, a future straightforward proof of principle experiment has been identified. To demonstrate non-resonant gas heating, a series of pulsed optical lattices were simulated interacting with neutral non-polar species. An optimum time between pulses was identified as a function of the collisional relaxation time. Using the optimum time between pulses, molecular nitrogen simulations showed an increase in gas temperature from 300 K to 2470 K at 1 atm, for 50 successive optical lattice pulses. A second proof of principle experiment was identified for future investigation.

Molecular candidates of MTV in air

NASA Astrophysics Data System (ADS)

Dam, Nico; Mirzaei, Mehrnoosh; van de Water, Willem

2011-11-01

In molecular tagging velocimetry (MTV), the molecules of a gas are used as flow tracers. These tracers can be produced at will by illumination with a laser which promotes molecules to a long- lived excited state, fuses N2 and N2 to NO, or makes molecules phosphoresce. A while later these tagged molecules can be visualized by laser-induced fluorescence, or by just watching them while they phosphoresce. Candidates for MTV in turbulence research must be arranged in structures narrower than the Kolmogorov scale, which remain narrow as time progresses, and must live longer than the Kolmogorov time. These requirements invalidate many candidates, candidates once deemed successful. They do so in various surprising manners that involve a combination of fluid flow and molecular dynamics. Rather than velocimetry in turbulence, MTV techniques offer a unique view on basic dispersion processes at the smallest scales of turbulence. In this way we have measured the spreading of clouds whose size is a few times the Kolmogorov length and the Batchelor dispersion of objects whose size is inside the inertial range.

Non-Intrusive Optical Diagnostic Methods for Flowfield Characterization

NASA Technical Reports Server (NTRS)

Tabibi, Bagher M.; Terrell, Charles A.; Spraggins, Darrell; Lee, Ja. H.; Weinstein, Leonard M.

1997-01-01

Non-intrusive optical diagnostic techniques such as Electron Beam Fluorescence (EBF), Laser-Induced Fluorescence (LIF), and Focusing Schlieren (FS) have been setup for high-speed flow characterization and large flowfield visualization, respectively. Fluorescence emission from the First Negative band of N2(+) with the (0,0) vibration transition (at lambda =391.44 nm) was obtained using the EBF technique and a quenching rate of N2(+)* molecules by argon gas was reported. A very high sensitivity FS system was built and applied in the High-Speed Flow Generator (HFG) at NASA LaRC. A LIF system is available at the Advanced Propulsion Laboratory (APL) on campus and a plume exhaust velocity measurement, measuring the Doppler shift from lambda = 728.7 nm of argon gas, is under way.

Comparing DNS and Experiments of Subcritical Flow Past an Isolated Surface Roughness Element

NASA Astrophysics Data System (ADS)

Doolittle, Charles; Goldstein, David

2009-11-01

Results are presented from computational and experimental studies of subcritical roughness within a Blasius boundary layer. This work stems from discrepancies presented by Stephani and Goldstein (AIAA Paper 2009-585) where DNS results did not agree with hot-wire measurements. The near wake regions of cylindrical surface roughness elements corresponding to roughness-based Reynolds numbers Rek of about 202 are of specific concern. Laser-Doppler anemometry and flow visualization in water, as well as the same spectral DNS code used by Stephani and Goldstein are used to obtain both quantitative and qualitative comparisons with previous results. Conclusions regarding previous studies will be presented alongside discussion of current work including grid resolution studies and an examination of vorticity dynamics.

Turbulent mixing induced by Richtmyer-Meshkov instability

NASA Astrophysics Data System (ADS)

Krivets, V. V.; Ferguson, K. J.; Jacobs, J. W.

2017-01-01

Richtmyer-Meshkov instability is studied in shock tube experiments with an Atwood number of 0.7. The interface is formed in a vertical shock tube using opposed gas flows, and three-dimensional random initial interface perturbations are generated by the vertical oscillation of gas column producing Faraday waves. Planar Laser Mie scattering is used for flow visualization and for measurements of the mixing process. Experimental image sequences are recorded at 6 kHz frequency and processed to obtain the time dependent variation of the integral mixing layer width. Measurements of the mixing layer width are compared with Mikaelian's [1] model in order to extract the growth exponent θ where a fairly wide range of values is found varying from θ ≈ 0.2 to 0.6.

NASA Low-Speed Centrifugal Compressor for Fundamental Research

NASA Technical Reports Server (NTRS)

Wood, J. R.; Adam, P. W.; Buggele, A. E.

1983-01-01

A centrifugal compressor facility being built by the NASA Lewis Research Center is described; its purpose is to obtain benchmark experimental data for internal flow code verification and modeling. The facility will be heavily instrumented with standard pressure and temperature probes and have provisions for flow visualization and laser Doppler velocimetry. The facility will accommodate rotational speeds to 2400 rpm and will be rated at pressures to 1.25 atm. The initial compressor stage for testing is geometrically and dynamically representative of modern high-performance stages with the exception of Mach number levels. Design exit tip speed for the initial stage is 500 ft/sec with a pressure ratio of 1.17. The rotor exit backsweep is 55 deg from radial.

Experimental investigation of the wake behind a rotating sphere

NASA Astrophysics Data System (ADS)

Skarysz, M.; Rokicki, J.; Goujon-Durand, S.; Wesfreid, J. E.

2018-01-01

The wake behind a sphere, rotating about an axis aligned with the streamwise direction, has been experimentally investigated in a low-velocity water tunnel using laser-induced fluorescence visualizations and particle image velocimetry measurements. The measurements focused on the evolution of the flow regimes that appear depending on two control parameters: the Reynolds number Re and the dimensionless rotation or swirl rate Ω , which is the ratio of the maximum azimuthal velocity of the body to the free-stream velocity. In the present investigation, we cover the range of Re smaller than 400 and Ω from 0 and 4. Different wakes regimes such as an axisymmetric flow, a low helical state, and a high helical mode are represented in the (Re, Ω ) parameter plane.

Randomized Trial Evaluating Ranibizumab Plus Prompt or Deferred Laser or Triamcinolone Plus Prompt Laser for Diabetic Macular Edema

PubMed Central

Elman, Michael J.; Aiello, Lloyd Paul; Beck, Roy W.; Bressler, Neil M.; Bressler, Susan B.; Edwards, Allison R.; Ferris, Frederick L.; Friedman, Scott M.; Glassman, Adam R.; Miller, Kellee M.; Scott, Ingrid U.; Stockdale, Cynthia R.; Sun, Jennifer K.

2010-01-01

Objective Evaluate intravitreal 0.5 mg ranibizumab or 4 mg triamcinolone combined with focal/grid laser compared with focal/grid laser alone for treatment of diabetic macular edema (DME). Design Multicenter, randomized clinical trial. Participants A total of 854 study eyes of 691 participants with visual acuity (approximate Snellen equivalent) of 20/32 to 20/320 and DME involving the fovea. Methods Eyes were randomized to sham injection + prompt laser (n=293), 0.5 mg ranibizumab + prompt laser (n=187), 0.5 mg ranibizumab + deferred (≥24 weeks) laser (n=188), or 4 mg triamcinolone + prompt laser (n=186). Retreatment followed an algorithm facilitated by a web-based, real-time data-entry system. Main Outcome Measures Best-corrected visual acuity and safety at 1 year. Results The 1-year mean change (±standard deviation) in the visual acuity letter score from baseline was significantly greater in the ranibizumab + prompt laser group (+9±11, P<0.001) and ranibizumab + deferred laser group (+9±12, P<0.001) but not in the triamcinolone + prompt laser group (+4±13, P=0.31) compared with the sham + prompt laser group (+3±13). Reduction in mean central subfield thickness in the triamcinolone + prompt laser group was similar to both ranibizumab groups and greater than in the sham + prompt laser group. In the subset of pseudophakic eyes at baseline (n=273), visual acuity improvement in the triamcinolone + prompt laser group appeared comparable to that in the ranibizumab groups. No systemic events attributable to study treatment were apparent. Three eyes (0.8%) had injection-related endophthalmitis in the ranibizumab groups, whereas elevated intraocular pressure and cataract surgery were more frequent in the triamcinolone + prompt laser group. Two-year visual acuity outcomes were similar to 1-year outcomes. Conclusions Intravitreal ranibizumab with prompt or deferred laser is more effective through at least 1 year compared with prompt laser alone for the treatment of DME involving the central macula. Ranibizumab as applied in this study, although uncommonly associated with endophthalmitis, should be considered for patients with DME and characteristics similar to those in this clinical trial. In pseudophakic eyes, intravitreal triamcinolone + prompt laser seems more effective than laser alone but frequently increases the risk of intraocular pressure elevation. PMID:20427088

Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema.

PubMed

Elman, Michael J; Aiello, Lloyd Paul; Beck, Roy W; Bressler, Neil M; Bressler, Susan B; Edwards, Allison R; Ferris, Frederick L; Friedman, Scott M; Glassman, Adam R; Miller, Kellee M; Scott, Ingrid U; Stockdale, Cynthia R; Sun, Jennifer K

2010-06-01

Evaluate intravitreal 0.5 mg ranibizumab or 4 mg triamcinolone combined with focal/grid laser compared with focal/grid laser alone for treatment of diabetic macular edema (DME). Multicenter, randomized clinical trial. A total of 854 study eyes of 691 participants with visual acuity (approximate Snellen equivalent) of 20/32 to 20/320 and DME involving the fovea. Eyes were randomized to sham injection + prompt laser (n=293), 0.5 mg ranibizumab + prompt laser (n=187), 0.5 mg ranibizumab + deferred (> or =24 weeks) laser (n=188), or 4 mg triamcinolone + prompt laser (n=186). Retreatment followed an algorithm facilitated by a web-based, real-time data-entry system. Best-corrected visual acuity and safety at 1 year. The 1-year mean change (+/-standard deviation) in the visual acuity letter score from baseline was significantly greater in the ranibizumab + prompt laser group (+9+/-11, P<0.001) and ranibizumab + deferred laser group (+9+/-12, P<0.001) but not in the triamcinolone + prompt laser group (+4+/-13, P=0.31) compared with the sham + prompt laser group (+3+/-13). Reduction in mean central subfield thickness in the triamcinolone + prompt laser group was similar to both ranibizumab groups and greater than in the sham + prompt laser group. In the subset of pseudophakic eyes at baseline (n=273), visual acuity improvement in the triamcinolone + prompt laser group appeared comparable to that in the ranibizumab groups. No systemic events attributable to study treatment were apparent. Three eyes (0.8%) had injection-related endophthalmitis in the ranibizumab groups, whereas elevated intraocular pressure and cataract surgery were more frequent in the triamcinolone + prompt laser group. Two-year visual acuity outcomes were similar to 1-year outcomes. Intravitreal ranibizumab with prompt or deferred laser is more effective through at least 1 year compared with prompt laser alone for the treatment of DME involving the central macula. Ranibizumab as applied in this study, although uncommonly associated with endophthalmitis, should be considered for patients with DME and characteristics similar to those in this clinical trial. In pseudophakic eyes, intravitreal triamcinolone + prompt laser seems more effective than laser alone but frequently increases the risk of intraocular pressure elevation. Copyright 2010 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

Mass spectrometry imaging for visualizing organic analytes in food.

PubMed

Handberg, Eric; Chingin, Konstantin; Wang, Nannan; Dai, Ximo; Chen, Huanwen

2015-01-01

The demand for rapid chemical imaging of food products steadily increases. Mass spectrometry (MS) is featured by excellent molecular specificity of analysis and is, therefore, a very attractive method for chemical profiling. MS for food imaging has increased significantly over the past decade, aided by the emergence of various ambient ionization techniques that allow direct and rapid analysis in ambient environment. In this article, the current status of food imaging with MSI is reviewed. The described approaches include matrix-assisted laser desorption/ionization (MALDI), but emphasize desorption atmospheric pressure photoionization (DAPPI), electrospray-assisted laser desorption/ionization (ELDI), probe electrospray ionization (PESI), surface desorption atmospheric pressure chemical ionization (SDAPCI), and laser ablation flowing atmospheric pressure afterglow (LA-FAPA). The methods are compared with regard to spatial resolution; analysis speed and time; limit of detection; and technical aspects. The performance of each method is illustrated with the description of a related application. Specific requirements in food imaging are discussed. © 2014 Wiley Periodicals, Inc.

Visualization of evolving laser-generated structures by frequency domain tomography

NASA Astrophysics Data System (ADS)

Chang, Yenyu; Li, Zhengyan; Wang, Xiaoming; Zgadzaj, Rafal; Downer, Michael

2011-10-01

We introduce frequency domain tomography (FDT) for single-shot visualization of time-evolving refractive index structures (e.g. laser wakefields, nonlinear index structures) moving at light-speed. Previous researchers demonstrated single-shot frequency domain holography (FDH), in which a probe-reference pulse pair co- propagates with the laser-generated structure, to obtain snapshot-like images. However, in FDH, information about the structure's evolution is averaged. To visualize an evolving structure, we use several frequency domain streak cameras (FDSCs), in each of which a probe-reference pulse pair propagates at an angle to the propagation direction of the laser-generated structure. The combination of several FDSCs constitutes the FDT system. We will present experimental results for a 4-probe FDT system that has imaged the whole-beam self-focusing of a pump pulse propagating through glass in a single laser shot. Combining temporal and angle multiplexing methods, we successfully processed data from four probe pulses in one spectrometer in a single-shot. The output of data processing is a multi-frame movie of the self- focusing pulse. Our results promise the possibility of visualizing evolving laser wakefield structures that underlie laser-plasma accelerators used for multi-GeV electron acceleration.

Software for visualization, analysis, and manipulation of laser scan images

NASA Astrophysics Data System (ADS)

Burnsides, Dennis B.

1997-03-01

The recent introduction of laser surface scanning to scientific applications presents a challenge to computer scientists and engineers. Full utilization of this two- dimensional (2-D) and three-dimensional (3-D) data requires advances in techniques and methods for data processing and visualization. This paper explores the development of software to support the visualization, analysis and manipulation of laser scan images. Specific examples presented are from on-going efforts at the Air Force Computerized Anthropometric Research and Design (CARD) Laboratory.

PLIF Visualization of Active Control of Hypersonic Boundary Layers Using Blowing

NASA Technical Reports Server (NTRS)

Bathel, Brett F.; Danehy, Paul M.; Inman, Jennifer A.; Alderfer, David W.; Berry, Scott A.

2008-01-01

Planar laser-induced fluorescence (PLIF) imaging was used to visualize the boundary layer flow on a 1/3-scale Hyper-X forebody model. The boundary layer was perturbed by blowing out of orifices normal to the model surface. Two blowing orifice configurations were used: a spanwise row of 17-holes spaced at 1/8 inch, with diameters of 0.020 inches and a single-hole orifice with a diameter of 0.010 inches. The purpose of the study was to visualize and identify laminar and turbulent structures in the boundary layer and to make comparisons with previous phosphor thermography measurements of surface heating. Jet penetration and its influence on the boundary layer development was also examined as was the effect of a compression corner on downstream boundary layer transition. Based upon the acquired PLIF images, it was determined that global surface heating measurements obtained using the phosphor thermography technique provide an incomplete indicator of transitional and turbulent behavior of the corresponding boundary layer flow. Additionally, the PLIF images show a significant contribution towards transition from instabilities originating from the underexpanded jets. For this experiment, a nitric oxide/nitrogen mixture was seeded through the orifices, with nitric oxide (NO) serving as the fluorescing gas. The experiment was performed in the 31-inch Mach 10 Air Tunnel at NASA Langley Research Center.

New test techniques and analytical procedures for understanding the behavior of advanced propellers

NASA Technical Reports Server (NTRS)

Stefko, G. L.; Bober, L. J.; Neumann, H. E.

1983-01-01

Analytical procedures and experimental techniques were developed to improve the capability to design advanced high speed propellers. Some results from the propeller lifting line and lifting surface aerodynamic analysis codes are compared with propeller force data, probe data and laser velocimeter data. In general, the code comparisons with data indicate good qualitative agreement. A rotating propeller force balance demonstrated good accuracy and reduced test time by 50 percent. Results from three propeller flow visualization techniques are shown which illustrate some of the physical phenomena occurring on these propellers.

NASA Lewis 9- by 15-foot low-speed wind tunnel user manual

NASA Technical Reports Server (NTRS)

Soeder, Ronald H.

1993-01-01

This manual describes the 9- by 15-Foot Low-Speed Wind Tunnel at the Lewis Research Center and provides information for users who wish to conduct experiments in this atmospheric facility. Tunnel variables such as pressures, temperatures, available tests section area, and Mach number ranges (0.05 to 0.20) are discussed. In addition, general support systems such as air systems, hydraulic system, hydrogen system, laser system, flow visualization system, and model support systems are described. Instrumentation and data processing and acquisition systems are also discussed.

Summary of an experimental investigation on the ground vortex

NASA Technical Reports Server (NTRS)

Billet, Michael L.; Cimbala, John M.

1988-01-01

The results of an experimental investigation into the position and characteristics of the ground vortex are summarized. A 48-inch wind tunnel was modified to create a testing environment suitable for the ground vortex study. Flow visualization was used to document the jet-crossflow interaction and a two-component Laser Doppler Velocimeter (LDV) was used to survey the flowfield in detail. Measurements of the ground vortex characteristics and location as a function of freestream-to-jet velocity ratio, jet height, pressure gradient and upstream boundary layer thickness were obtained.

Nanoparticle coated optical fibers for single microbubble generation

NASA Astrophysics Data System (ADS)

Pimentel-Domínguez, Reinher; Hernández-Cordero, Juan

2011-09-01

The study of bubbles and bubbly flows is important in various fields such as physics, chemistry, medicine, geophysics, and even the food industry. A wide variety of mechanical and acoustic techniques have been reported for bubble generation. Although a single bubble may be generated with these techniques, controlling the size and the mean lifetime of the bubble remains a difficult task. Most of the optical methods for generation of microbubbles involve high-power pulsed laser sources focused in absorbing media such as liquids or particle solutions. With these techniques, single micron-sized bubbles can be generated with typical mean lifetimes ranging from nano to microseconds. The main problem with these bubbles is their abrupt implosion: this produces a shock wave that can potentially produce damages on the surroundings. These effects have to be carefully controlled in biological applications and in laser surgery, but thus far, not many options are available to effectively control micron-size bubble growth. In this paper, we present a new technique to generate microbubbles in non-absorbing liquids. In contrast to previous reports, the proposed technique uses low-power and a CW radiation from a laser diode. The laser light is guided through an optical fiber whose output end has been coated with nanostructures. Upon immersing the tip of the fiber in ethanol or water, micron-size bubbles can be readily generated. With this technique, bubble growth can be controlled through adjustments on the laser power. We have obtained micron-sized bubbles with mean lifetimes in the range of seconds. Furthermore, the generated bubbles do not implode, as verified with a high-speed camera and flow visualization techniques.

Comparison of three techniques for evaluating skin erythemal response for determination of sun protection factors of sunscreens: high resolution laser Doppler imaging, colorimetry and visual scoring.

PubMed

Wilhelm, K P; Kaspar, K; Funkel, O

2001-04-01

Sun protection factor (SPF) measurement is based on the determination of the minimal erythema dose (MED). The ratio of doses required to induce a minimal erythema between product-treated and untreated skin is defined as SPF. The aim of this study was to validate the conventionally used visual scoring with two non-invasive methods: high resolution laser Doppler imaging (HR-LDI) and colorimetry. Another goal was to check whether suberythemal reactions could be detected by means of HR-LDI measurements. Four sunscreens were selected. The measurements were made on the back of 10 subjects. A solar simulator SU 5000 (m.u.t., Wedel, Germany) served as radiation source. For the visual assessment, the erythema was defined according to COLIPA as the first perceptible, clearly defined unambiguous redness of the skin. For the colorimetric determination of the erythema, a Chromameter CR 300 (Minolta, Osaka, Japan) was used. The threshold for the colorimetry was chosen according to the COLIPA recommendation as an increase of the redness parameter delta a* = 2.5. For the non-contact perfusion measurements of skin blood flow, a two-dimensional high resolution laser Doppler imager (HR-LDI) (Lisca, Linköping, Sweden) was used. For the HR-LDI measurements, an optimal threshold perfusion needed to be established. For the HR-LDI measurements basal perfusion +1 standard deviation of all basal measurements was found to be a reliable threshold perfusion corresponding to the minimal erythema. Smaller thresholds, which would be necessary for detection of suberythemal responses, did not provide unambiguous data. All three methods, visual scoring, colorimetry and HR-LDI, produced similar SPFs for the test products with a variability of < 5% between methods. The HR-LDI method showed the lowest variation of the mean SPF. Neither of the instrumental methods, however, resulted in an increase of the sensitivity of SPF determination as compared with visual scoring. Both HR-LDI and colorimetry are suitable, reliable and observer-independent methods for MED determination. However, they do not provide greater sensitivity and thus do not result in lower UV dose requirements for testing.

Development of a New Hypersonic Shock Tunnel Facility to Investigate Electromagnetic Energy Addition for Flow Control and Basic Supersonic Combustion

NASA Astrophysics Data System (ADS)

Toro, P. G. P.; Minucci, M. A. S.; Chanes, J. B.; Pereira, A. L.; Nagamatsu, H. T.

2006-05-01

A new 0.6-m. diameter Hypersonic Shock Tunnel is been designed, fabricated and will be installed at the Laboratory of Aerothermodynamics and Hypersonics IEAv-CTA, Brazil. The brand new hypersonic facility, designated as T3, is primarily intended to be used as an important tool in the investigation of supersonic combustion management and of electromagnetic energy addition for flow control. The design of the runnel enables relatively long test times, 2-10 milliseconds, suitable for basic supersonic combustion and energy addition by laser experiments. Free stream Mach numbers ranging from 6 to 25 can be produced and stagnation pressures and temperatures of 200 atm. and 5,500 K, respectively, can be generated. Shadowgraph and schlieren optical techniques will be used for flow visualization and the new facility is expected to be commissioned by the end of 2006.

Vortex breakdown in closed containers with polygonal cross sections

DOE Office of Scientific and Technical Information (OSTI.GOV)

Naumov, I. V., E-mail: naumov@itp.nsc.ru; Dvoynishnikov, S. V.; Kabardin, I. K.

2015-12-15

The vortex breakdown bubble in the confined flow generated by a rotating lid in closed containers with polygonal cross sections was analysed both experimentally and numerically for the height/radius aspect ratio equal to 2. The stagnation point locations of the breakdown bubble emergence and the corresponding Reynolds number were determined experimentally and in addition computed numerically by STAR-CCM+ CFD software for square, pentagonal, hexagonal, and octagonal cross section configurations. The flow pattern and the velocity were observed and measured by combining the seeding particle visualization and the temporal accuracy of laser Doppler anemometry. The vortex breakdown size and position onmore » the container axis were determined for Reynolds numbers, ranging from 1450 to 2400. The obtained results were compared with the flow structure in the closed container of cubical and cylindrical configurations. It is shown that the measured evolution of steady vortex breakdown is in close agreement with the numerical results.« less

The structure of separated flow regions occurring near the leading edge of airfoils - including transition

NASA Technical Reports Server (NTRS)

1989-01-01

Laser Doppler Velocimeter data, static pressure data, and smoke flow visualization data was obtained and analyzed to correlate with separation bubble data. The Eppler 387 airfoil was focused on at a chord Reynolds number of 100,000 and an angle of attack of 2 deg. Additional data was also obtained from the NACA 663-018 airfoil at a chord Reynolds number of 160,000 and an angle of attack of 12 deg. The structure and behavior of the transition separation bubble was documented along with the redeveloping boundary layer after reattachment over an airfoil at low Reynolds numbers. The understanding of the complex flow phenomena was examined so that analytic methods for predicting their formation and development can be improved. These analytic techniques have applications in the design and performance prediction of airfoils operating in the low Reynolds number flight regime.

Secondary flow measurements and passive tracer dispersion in multi-generational models of conducting airways of the lung

NASA Astrophysics Data System (ADS)

Fresconi, Frank; Prasad, Ajay

2006-11-01

A detailed knowledge of the flow and dispersion within the human respiratory tract is desirable for numerous reasons. Both risk assessments of exposure to toxic particles in the environment and the design of medical delivery systems targeting both lung-specific conditions (asthma, cystic fibrosis, and chronic obstructive pulmonary disease (COPD)) and system-wide ailments (diabetes, cancer, hormone replacement) would profit from such an understanding. The present work features experimental efforts aimed at elucidating the fluid mechanics of the lung. Particle image velocimetry (PIV) and laser induced fluorescence (LIF) measurements of steady and oscillatory flows were undertaken in anatomically accurate models (single and multi-generational) of the conductive region of the lung. PIV results captured primary and secondary velocity fields. LIF allowed visualization of the time-dependent deformation of a passive tracer and also quantified convective dispersion through the usage of a transport profile.

PIV and LDA measurements of the wake behind a wind turbine model

NASA Astrophysics Data System (ADS)

Naumov, I. V.; Mikkelsen, R. F.; Okulov, V. L.; Sørensen, J. N.

2014-06-01

In the present work we review the results of a series of measurements of the flow behind a model scale of a horizontal axis wind turbine rotor carried out at the water flume at Technical University of Denmark (DTU). The rotor is three-bladed and designed using Glauert theory for tip speed ratio λ =5 with a constant design lift coefficient along the span, CLdesign= 0.8. The measurements include dye visualization, Particle Image Velocimetry and Laser Doppler Anemometry. The wake instability has been studied in the range λ =3 - 9 at different cross-sections from the very near wake up to 10 rotor diameters downstream from the rotor. The initial flume flow was subject to a very low turbulence level with a uniform velocity profile, limiting the influence of external disturbances on the development of the inherent vortex instability. Using PIV measurements and visualizations, special attention was paid to detect and categorize different types of wake instabilities and the development of the flow in the near and the far wake. In parallel to PIV, LDA measurements provided data for various rotor regimes, revealing the existence of three main regular frequencies governing the development of different processes and instabilities in the rotor wake. In the far wake a constant frequency corresponding to the Strouhal number was found for the long-scale instabilities. This Strouhal number is in good agreement with the well-known constant that usually characterizes the oscillation in wakes behind bluff bodies. From associated visualizations and reconstructions of the flow field, it was found that the dynamics of the far wake is associated with the precession (rotation) of a helical vortex core. The data indicate that Strouhal number of this precession is independent of the rotor angular speed.

Visualization of femtosecond laser pulse-induced microincisions inside crystalline lens tissue.

PubMed

Stachs, Oliver; Schumacher, Silvia; Hovakimyan, Marine; Fromm, Michael; Heisterkamp, Alexander; Lubatschowski, Holger; Guthoff, Rudolf

2009-11-01

To evaluate a new method for visualizing femtosecond laser pulse-induced microincisions inside crystalline lens tissue. Laser Zentrum Hannover e.V., Hannover, Germany. Lenses removed from porcine eyes were modified ex vivo by femtosecond laser pulses (wavelength 1040 nm, pulse duration 306 femtoseconds, pulse energy 1.0 to 2.5 microJ, repetition rate 100 kHz) to create defined planes at which lens fibers separate. The femtosecond laser pulses were delivered by a 3-dimension (3-D) scanning unit and transmitted by focusing optics (numerical aperture 0.18) into the lens tissue. Lens fiber orientation and femtosecond laser-induced microincisions were examined using a confocal laser scanning microscope (CLSM) based on a Rostock Cornea Module attached to a Heidelberg Retina Tomograph II. Optical sections were analyzed in 3-D using Amira software (version 4.1.1). Normal lens fibers showed a parallel pattern with diameters between 3 microm and 9 microm, depending on scanning location. Microincision visualization showed different cutting effects depending on pulse energy of the femtosecond laser. The effects ranged from altered tissue-scattering properties with all fibers intact to definite fiber separation by a wide gap. Pulse energies that were too high or overlapped too tightly produced an incomplete cutting plane due to extensive microbubble generation. The 3-D CLSM method permitted visualization and analysis of femtosecond laser pulse-induced microincisions inside crystalline lens tissue. Thus, 3-D CLSM may help optimize femtosecond laser-based procedures in the treatment of presbyopia.

Experimental Investigation of a Helicopter Rotor Hub Flow

NASA Astrophysics Data System (ADS)

Reich, David

The rotor hub system is by far the largest contributor to helicopter parasite drag and a barrier to increasing helicopter forward-flight speed and range. Additionally, the hub sheds undesirable vibration- and instability-inducing unsteady flow over the empennage. The challenges associated with rotor hub flows are discussed, including bluff body drag, interactional aerodynamics, and the effect of the turbulent hub wake on the helicopter empennage. This study was conducted in three phases to quantify model-scale rotor hub flows in water tunnels at The Pennsylvania State University Applied research lab. The first phase investigated scaling and component interaction effects on a 1:17 scale rotor hub model in the 12-inch diameter water tunnel. Effects of Reynolds number, advance ratio, and hub geometry configuration on the drag and wake shed from the rotor hub were quantified using load cell measurements and particle-image velocimetry (PIV). The second phase focused on flow visualization and measurement on a rotor hub and rotor hub/pylon geometry in the 12-inch diameter water tunnel. Stereo PIV was conducted in a cross plane downstream of the hub and flow visualization was conducted using oil paint and fluorescent dye. The third phase concentrated on high accuracy load measurement and prediction up to full-scale Reynolds number on a 1:4.25 scale model in the 48-inch diameter water tunnel. Measurements include 6 degree of freedom loads on the hub and two-component laser-Doppler velocimetry in the wake. Finally, results and conclusions are discussed, followed by recommendations for future investigations.

Laser streaming: Turning a laser beam into a flow of liquid

PubMed Central

Wang, Yanan; Zhang, Qiuhui; Zhu, Zhuan; Lin, Feng; Deng, Jiangdong; Ku, Geng; Dong, Suchuan; Song, Shuo; Alam, Md Kamrul; Liu, Dong; Wang, Zhiming; Bao, Jiming

2017-01-01

Transforming a laser beam into a mass flow has been a challenge both scientifically and technologically. We report the discovery of a new optofluidic principle and demonstrate the generation of a steady-state water flow by a pulsed laser beam through a glass window. To generate a flow or stream in the same path as the refracted laser beam in pure water from an arbitrary spot on the window, we first fill a glass cuvette with an aqueous solution of Au nanoparticles. A flow will emerge from the focused laser spot on the window after the laser is turned on for a few to tens of minutes; the flow remains after the colloidal solution is completely replaced by pure water. Microscopically, this transformation is made possible by an underlying plasmonic nanoparticle-decorated cavity, which is self-fabricated on the glass by nanoparticle-assisted laser etching and exhibits size and shape uniquely tailored to the incident beam profile. Hydrophone signals indicate that the flow is driven via acoustic streaming by a long-lasting ultrasound wave that is resonantly generated by the laser and the cavity through the photoacoustic effect. The principle of this light-driven flow via ultrasound, that is, photoacoustic streaming by coupling photoacoustics to acoustic streaming, is general and can be applied to any liquid, opening up new research and applications in optofluidics as well as traditional photoacoustics and acoustic streaming. PMID:28959726

Laser streaming: Turning a laser beam into a flow of liquid.

PubMed

Wang, Yanan; Zhang, Qiuhui; Zhu, Zhuan; Lin, Feng; Deng, Jiangdong; Ku, Geng; Dong, Suchuan; Song, Shuo; Alam, Md Kamrul; Liu, Dong; Wang, Zhiming; Bao, Jiming

2017-09-01

Transforming a laser beam into a mass flow has been a challenge both scientifically and technologically. We report the discovery of a new optofluidic principle and demonstrate the generation of a steady-state water flow by a pulsed laser beam through a glass window. To generate a flow or stream in the same path as the refracted laser beam in pure water from an arbitrary spot on the window, we first fill a glass cuvette with an aqueous solution of Au nanoparticles. A flow will emerge from the focused laser spot on the window after the laser is turned on for a few to tens of minutes; the flow remains after the colloidal solution is completely replaced by pure water. Microscopically, this transformation is made possible by an underlying plasmonic nanoparticle-decorated cavity, which is self-fabricated on the glass by nanoparticle-assisted laser etching and exhibits size and shape uniquely tailored to the incident beam profile. Hydrophone signals indicate that the flow is driven via acoustic streaming by a long-lasting ultrasound wave that is resonantly generated by the laser and the cavity through the photoacoustic effect. The principle of this light-driven flow via ultrasound, that is, photoacoustic streaming by coupling photoacoustics to acoustic streaming, is general and can be applied to any liquid, opening up new research and applications in optofluidics as well as traditional photoacoustics and acoustic streaming.

High power gas laser - Applications and future developments

NASA Technical Reports Server (NTRS)

Hertzberg, A.

1977-01-01

Fast flow can be used to create the population inversion required for lasing action, or can be used to improve laser operation, for example by the removal of waste heat. It is pointed out that at the present time all lasers which are capable of continuous high-average power employ flow as an indispensable aspect of operation. High power laser systems are discussed, taking into account the gasdynamic laser, the HF supersonic diffusion laser, and electric discharge lasers. Aerodynamics and high power lasers are considered, giving attention to flow effects in high-power gas lasers, aerodynamic windows and beam manipulation, and the Venus machine. Applications of high-power laser technology reported are related to laser material working, the employment of the laser in controlled fusion machines, laser isotope separation and photochemistry, and laser power transmission.

Lipid tubules Formed by Flow-Controlled Hydration

NASA Astrophysics Data System (ADS)

Yuan, Jing; Hirst, Linda S.

2007-03-01

Self-assembled cylindrical tubules from lipid molecules have attracted considerable attention because of their interesting supramolecular structures and technological applications. Schnur et al. [1] reported the formation of tubular microstructures from a series of diacetylenic phospholipids after liposomes were cooled through their chain melting transition. After that, several methods have been developed to fabricate such unique microstructures mainly by means of deforming preformed Giant unilamellar vesicles. Here we present a simple strategy to construct lipid microtubules through a flow-controlled lipid hydration. Fluorescent microscopy and Confocal Laser Microscopy were used to visualize the formation and the structure of the lipid tubules. Tubules were found to develop following the direction of the dynamic flow with highly parallel alignment. At high flow speeds, partial cross-linking of the lipid tubules was observed. To demonstrate the generality of this method, different types of phospholipids, such as Phosphatidic Acid (PA), Phosphatidylserine (PS), Phosphatidylethanolamine (PE), and Phosphatidylglycerol (PG) were investigated. [1] J.M. Schnur et al, Science, 264, 945 (1994).

Nerve fiber layer (NFL) degeneration associated with acute q-switched laser exposure in the nonhuman primate

NASA Astrophysics Data System (ADS)

Zwick, Harry; Zuclich, Joseph A.; Stuck, Bruce E.; Gagliano, Donald A.; Lund, David J.; Glickman, Randolph D.

1995-01-01

We have evaluated acute laser retinal exposure in non-human primates using a Rodenstock scanning laser ophthalmoscope (SLO) equipped with spectral imaging laser sources at 488, 514, 633, and 780 nm. Confocal spectral imaging at each laser wavelength allowed evaluation of the image plane from deep within the retinal vascular layer to the more superficial nerve fiber layer in the presence and absence of the short wavelength absorption of the macular pigment. SLO angiography included both fluorescein and indocyanine green procedures to assess the extent of damage to the sensory retina, the retinal pigment epithelium (RPE), and the choroidal vasculature. All laser exposures in this experiment were from a Q-switched Neodymium laser source at an exposure level sufficient to produce vitreous hemorrhage. Confocal imaging of the nerve fiber layer revealed discrete optic nerve sector defects between the lesion site and the macula (retrograde degeneration) as well as between the lesion site and the optic disk (Wallerian degeneration). In multiple hemorrhagic exposures, lesions placed progressively distant from the macula or overlapping the macula formed bridging scars visible at deep retinal levels. Angiography revealed blood flow disturbance at the retina as well as at the choroidal vascular level. These data suggest that acute parafoveal laser retinal injury can involve both direct full thickness damage to the sensory and non-sensory retina and remote nerve fiber degeneration. Such injury has serious functional implications for both central and peripheral visual function.

Changes in vision related quality of life in patients with diabetic macular edema: ranibizumab or laser treatment?

PubMed

Turkoglu, Elif Betul; Celık, Erkan; Aksoy, Nilgun; Bursalı, Ozlem; Ucak, Turgay; Alagoz, Gursoy

2015-01-01

To compare the changes in vision related quality of life (VR-QoL) in patients with diabetic macular edema (DME) undergoing intravitreal ranibizumab (IVR) injection or focal/grid laser. In this prospective study, 70 patients with clinically significant macular edema (CSME) were randomized to undergo IVR injection (n=35) and focal/grid laser (n=35). If necessary, the laser or ranibizumab injections were repeated. Distance and near visual acuities, central retinal thickness (CRT) and The 25-item Visual Function Questionnaire (VFQ-25) were used to measure the effectiveness of treatments and VR-QoL before and after 6 months following IVR or laser treatment. The demographic and clinical findings before the treatments were similar in both main groups. The improvements in distance and near visual acuities were higher in IVR group than the laser group (p<0.01). The reduction in CRT in IVR group was higher than that in laser treatment group (p<0.01). In both groups, the VFQ-25 composite score tended to improve from baseline to 6 months. And at 6th month, the changes in composite score were significantly higher in IVR group than in laser group (p<0.05). The improvements in overall composite scores were 6.3 points for the IVR group compared with 3.0 points in the laser group. Patients treated with IVR and laser had large improvements in composite scores, general vision, near and distance visual acuities in VFQ-25 at 6 months, in comparison with baseline scores, and also mental health subscale in IVR group. Our study revealed that IVR improved not only visual acuity or CRT, but also vision related quality of life more than laser treatment in DME. And these patient-reported outcomes may play an important role in the treatment choice in DME for clinicians. Copyright © 2015 Elsevier Inc. All rights reserved.

Visualizing fossilization using laser ablation-inductively coupled plasma-mass spectrometry maps of trace elements in Late Cretaceous bones

USGS Publications Warehouse

Koenig, A.E.; Rogers, R.R.; Trueman, C.N.

2009-01-01

Elemental maps generated by laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) provide a previously unavailable high-resolution visualization of the complex physicochemical conditions operating within individual bones during the early stages of diagenesis and fossilization. A selection of LA-ICP-MS maps of bones collected from the Late Cretaceous of Montana (United States) and Madagascar graphically illustrate diverse paths to recrystallization, and reveal unique insights into geochemical aspects of taphonomic history. Some bones show distinct gradients in concentrations of rare earth elements and uranium, with highest concentrations at external bone margins. Others exhibit more intricate patterns of trace element uptake related to bone histology and its control on the flow paths of pore waters. Patterns of element uptake as revealed by LA-ICP-MS maps can be used to guide sampling strategies, and call into question previous studies that hinge upon localized bulk samples of fossilized bone tissue. LA-ICP-MS maps also allow for comparison of recrystallization rates among fossil bones, and afford a novel approach to identifying bones or regions of bones potentially suitable for extracting intact biogeochemical signals. ?? 2009 Geological Society of America.

Rolling up of Large-scale Laminar Vortex Ring from Synthetic Jet Impinging onto a Wall

NASA Astrophysics Data System (ADS)

Xu, Yang; Pan, Chong; Wang, Jinjun; Flow Control Lab Team

2015-11-01

Vortex ring impinging onto a wall exhibits a wide range of interesting behaviors. The present work devotes to an experimental investigation of a series of small-scale vortex rings impinging onto a wall. These laminar vortex rings were generated by a piston-cylinder driven synthetic jet in a water tank. Laser Induced Fluorescence (LIF) and Particle Image Velocimetry (PIV) were used for flow visualization/quantification. A special scenario of vortical dynamic was found for the first time: a large-scale laminar vortex ring is formed above the wall, on the outboard side of the jet. This large-scale structure is stable in topology pattern, and continuously grows in strength and size along time, thus dominating dynamics of near wall flow. To quantify its spatial/temporal characteristics, Finite-Time Lyapunov Exponent (FTLE) fields were calculated from PIV velocity fields. It is shown that the flow pattern revealed by FTLE fields is similar to the visualization. The size of this large-scale vortex ring can be up to one-order larger than the jet vortices, and its rolling-up speed and entrainment strength was correlated to constant vorticity flux issued from the jet. This work was supported by the National Natural Science Foundation of China (Grants No.11202015 and 11327202).

NO PLIF Visualizations of the Orion Capsule in LENS-I

NASA Technical Reports Server (NTRS)

Combs, C.; Clemens, N.; Danehy, P. M.; Bathel, B.; Parker, R.; Wadhams, T.; Holden, M.; Kirk, B.

2013-01-01

Planar laser-induced fluorescence (PLIF) of nitric oxide (NO) was used to visualize the interaction of reaction-control-system (RCS) jet flows in the wake of a hypersonic capsule reentry vehicle. The tests were performed at the Calspan University at Buffalo Research Center's (CUBRC) LENS-I reflected shock tunnel facility. This was the first application of PLIF to study RCS jets in a large-scale pulsed hypersonic facility. The LENS-I facility allowed RCS jet flows to be studied while varying the flow enthalpy, Reynolds number, angle of attack and jet configuration. The interaction of pitch and roll jets with the flowfield was investigated. Additionally, thin film sensors were used to monitor heat transfer on the surface of the model to detect any localized heating resulting from the firing of the RCS jets. Tests were conducted with the model held at angles of attack of 18deg and 22deg. The nominal Mach number in all tests was 8, while Reynolds number based on model diameter ranged from 2.2x10(exp 6) - 1.5x10(exp 7). Images were processed using the Virtual Diagnostics Interface (ViDI) system developed at NASA Langley Research Center to provide a three-dimensional display of the experimental data.

Navigated macular laser decreases retreatment rate for diabetic macular edema: a comparison with conventional macular laser.

PubMed

Neubauer, Aljoscha S; Langer, Julian; Liegl, Raffael; Haritoglou, Christos; Wolf, Armin; Kozak, Igor; Seidensticker, Florian; Ulbig, Michael; Freeman, William R; Kampik, Anselm; Kernt, Marcus

2013-01-01

The purpose of this study was to evaluate and compare clinical outcomes and retreatment rates using navigated macular laser versus conventional laser for the treatment of diabetic macular edema (DME). In this prospective, interventional pilot study, 46 eyes from 46 consecutive patients with DME were allocated to receive macular laser photocoagulation using navigated laser. Best corrected visual acuity and retreatment rate were evaluated for up to 12 months after treatment. The control group was drawn based on chart review of 119 patients treated by conventional laser at the same institutions during the same time period. Propensity score matching was performed with Stata, based on the nearest-neighbor method. Propensity score matching for age, gender, baseline visual acuity, and number of laser spots yielded 28 matched patients for the control group. Visual acuity after navigated macular laser improved from a mean 0.48 ± 0.37 logMAR by a mean +2.9 letters after 3 months, while the control group showed a mean -4.0 letters (P = 0.03). After 6 months, navigated laser maintained a mean visual gain of +3.3 letters, and the conventional laser group showed a slower mean increase to +1.9 letters versus baseline. Using Kaplan-Meier analysis, the laser retreatment rate showed separation of the survival curves after 2 months, with fewer retreatments in the navigated group than in the conventional laser group during the first 8 months (18% versus 31%, respectively, P = 0.02). The short-term results of this pilot study suggest that navigated macular photocoagulation is an effective technique and could be considered as a valid alternative to conventional slit-lamp laser for DME when focal laser photocoagulation is indicated. The observed lower retreatment rates with navigated retinal laser therapy in the first 8 months suggest a more durable treatment effect.

Clinical Outcomes of an Optimized Prolate Ablation Procedure for Correcting Residual Refractive Errors Following Laser Surgery.

PubMed

Chung, Byunghoon; Lee, Hun; Choi, Bong Joon; Seo, Kyung Ryul; Kim, Eung Kwon; Kim, Dae Yune; Kim, Tae-Im

2017-02-01

The purpose of this study was to investigate the clinical efficacy of an optimized prolate ablation procedure for correcting residual refractive errors following laser surgery. We analyzed 24 eyes of 15 patients who underwent an optimized prolate ablation procedure for the correction of residual refractive errors following laser in situ keratomileusis, laser-assisted subepithelial keratectomy, or photorefractive keratectomy surgeries. Preoperative ophthalmic examinations were performed, and uncorrected distance visual acuity, corrected distance visual acuity, manifest refraction values (sphere, cylinder, and spherical equivalent), point spread function, modulation transfer function, corneal asphericity (Q value), ocular aberrations, and corneal haze measurements were obtained postoperatively at 1, 3, and 6 months. Uncorrected distance visual acuity improved and refractive errors decreased significantly at 1, 3, and 6 months postoperatively. Total coma aberration increased at 3 and 6 months postoperatively, while changes in all other aberrations were not statistically significant. Similarly, no significant changes in point spread function were detected, but modulation transfer function increased significantly at the postoperative time points measured. The optimized prolate ablation procedure was effective in terms of improving visual acuity and objective visual performance for the correction of persistent refractive errors following laser surgery.

Static and Hypersonic Experimental Analysis of Impulse Generation in Air-Breathing Laser-Thermal Propulsion

NASA Astrophysics Data System (ADS)

Salvador, Israel Irone

The present research campaign centered on static and hypersonic experiments performed with a two-dimensional, repetitively-pulsed (RP) laser Lightcraft model. The future application of interest for this basic research endeavor is the laser launch of nano- and micro-satellites (i.e., 1-100 kg payloads) into Low Earth Orbit (LEO), at low-cost and "on-demand". This research began with an international collaboration on Beamed Energy Propulsion between the United States Air Force and Brazilian Air Force to conduct experiments at the Henry T. Nagamatsu Laboratory of Aerothermodynamics and Hypersonics (HTN-LAH). The laser propulsion (LP) experiments employed the T3 Hypersonic Shock Tunnel (HST), integrated with twin gigawatt pulsed Lumonics 620-TEA CO2 lasers to produce the required test conditions. Following an introduction of the pulsed laser thermal propulsion concept and a state-of-the-art review of the topic, the principal physical processes are outlined starting from the onset of the laser pulse and subsequent laser-induced air-breakdown, to the expansion and exhaust of the resulting blast wave. After installation of the 254 mm wide, 2D Lightcraft model into the T3 tunnel, static LP tests were performed under quiescent (no-flow) conditions at ambient pressures of 0.06, 0.15, 0.3 and 1 bar, using the T3 test-section/dump-tank as a vacuum chamber. Time-dependent surface pressure distributions were measured over the engine thrust-generating surfaces following laser energy deposition; the delivered impulse and momentum coupling coefficients (Cm) were calculated from that pressure data. A Schlieren visualization system (using a high-speed Cordin digital camera) captured the laser breakdown and blast wave expansion process. The 2D model's Cm performance of 600 to 3000 N/MW was 2.5-5x higher than theoretical projections available in the literature, but indeed in the realm of feasibility for static conditions. Also, these Cm values exceed that for smaller Lightcraft models (98 to 161 mm in diameter), probably due to the more efficient delivery of laser-induced blast wave energy across the 2D model's larger impulse surface area. Next, the hypersonic campaign was carried out, subjecting the 2D model to nominal Mach numbers ranging from 6 to 10. Again, time-dependent surface pressure distributions were recorded together with Schlieren movies of the flow field structure resulting from laser energy deposition. These visualizations of inlet and absorption chamber flowfields, enabled the qualitative analysis of important phenomena impacting laser-propelled hypersonic airbreathing flight. The laser-induced breakdown took an elongated vertically-oriented geometry, occurring off-surface and across the inlet's mid-channel---quite different from the static case in which the energy was deposited very near the shroud under-surface. The shroud under-surface pressure data indicated laser-induced increases of 0.7-0.9 bar with laser pulse energies of ˜170 J, off-shroud induced breakdown condition, and Mach number of 7. The results of this research corroborate the feasibility of laser powered, airbreathing flight with infinite specific impulse (Isp=infinity): i.e., without the need for propellant injection at the laser focus. Additionally, it is shown that further reductions in inlet air working fluid velocity---with attendant increases in static pressure and density---is necessary to generate higher absorption chamber pressure and engine impulse. Finally, building on lessons learned from the present work, the future research plan is laid out for: a) the present 2D model with full inlet forebody, exploring higher laser pulse energies and multi-pulse phenomena; b) a smaller, redesigned 2D model; c) a 254 mm diameter axisymmetric Lightcraft model; and, d) a laser-electromagnetic accelerator model, designed around a 2-Tesla pulsed electromagnet contracted under the present program.

Flow Charts: Visualization of Vector Fields on Arbitrary Surfaces

PubMed Central

Li, Guo-Shi; Tricoche, Xavier; Weiskopf, Daniel; Hansen, Charles

2009-01-01

We introduce a novel flow visualization method called Flow Charts, which uses a texture atlas approach for the visualization of flows defined over curved surfaces. In this scheme, the surface and its associated flow are segmented into overlapping patches, which are then parameterized and packed in the texture domain. This scheme allows accurate particle advection across multiple charts in the texture domain, providing a flexible framework that supports various flow visualization techniques. The use of surface parameterization enables flow visualization techniques requiring the global view of the surface over long time spans, such as Unsteady Flow LIC (UFLIC), particle-based Unsteady Flow Advection Convolution (UFAC), or dye advection. It also prevents visual artifacts normally associated with view-dependent methods. Represented as textures, Flow Charts can be naturally integrated into hardware accelerated flow visualization techniques for interactive performance. PMID:18599918

In vivo visualization method by absolute blood flow velocity based on speckle and fringe pattern using two-beam multipoint laser Doppler velocimetry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kyoden, Tomoaki, E-mail: kyouden@nc-toyama.ac.jp; Naruki, Shoji; Akiguchi, Shunsuke

Two-beam multipoint laser Doppler velocimetry (two-beam MLDV) is a non-invasive imaging technique able to provide an image of two-dimensional blood flow and has potential for observing cancer as previously demonstrated in a mouse model. In two-beam MLDV, the blood flow velocity can be estimated from red blood cells passing through a fringe pattern generated in the skin. The fringe pattern is created at the intersection of two beams in conventional LDV and two-beam MLDV. Being able to choose the depth position is an advantage of two-beam MLDV, and the position of a blood vessel can be identified in a three-dimensionalmore » space using this technique. Initially, we observed the fringe pattern in the skin, and the undeveloped or developed speckle pattern generated in a deeper position of the skin. The validity of the absolute velocity value detected by two-beam MLDV was verified while changing the number of layers of skin around a transparent flow channel. The absolute velocity value independent of direction was detected using the developed speckle pattern, which is created by the skin construct and two beams in the flow channel. Finally, we showed the relationship between the signal intensity and the fringe pattern, undeveloped speckle, or developed speckle pattern based on the skin depth. The Doppler signals were not detected at deeper positions in the skin, which qualitatively indicates the depth limit for two-beam MLDV.« less

Measuring Flow With Laser-Speckle Velocimetry

NASA Technical Reports Server (NTRS)

Smith, C. A.; Lourenco, L. M. M.; Krothapalli, A.

1988-01-01

Spatial resolution sufficient for calculation of vorticity.In laser-speckle velocimetry, pulsed or chopped laser beam expanded in one dimension by cylindrical lens to illuminate thin, fan-shaped region of flow measured. Flow seeded by small particles. Lens with optical axis perpendicular to illuminating beam forms image of illuminated particles on photographic plate. Speckle pattern of laser-illuminiated, seeded flow recorded in multiple-exposure photographs and processed to extract data on velocity field. Technique suited for study of vortical flows like those about helicopter rotor blades or airplane wings at high angles of attack.

Imaging of the human choroid with a 1.7 MHz A-scan rate FDML swept source OCT system

NASA Astrophysics Data System (ADS)

Gorczynska, I.; Migacz, J. V.; Jonnal, R.; Zawadzki, R. J.; Poddar, R.; Werner, J. S.

2017-02-01

We demonstrate OCT angiography (OCTA) and Doppler OCT imaging of the choroid in the eyes of two healthy volunteers and in a geographic atrophy case. We show that visualization of specific choroidal layers requires selection of appropriate OCTA methods. We investigate how imaging speed, B-scan averaging and scanning density influence visualization of various choroidal vessels. We introduce spatial power spectrum analysis of OCT en face angiographic projections as a method of quantitative analysis of choroicapillaris morphology. We explore the possibility of Doppler OCT imaging to provide information about directionality of blood flow in choroidal vessels. To achieve these goals, we have developed OCT systems utilizing an FDML laser operating at 1.7 MHz sweep rate, at 1060 nm center wavelength, and with 7.5 μm axial imaging resolution. A correlation mapping OCA method was implemented for visualization of the vessels. Joint Spectral and Time domain OCT (STdOCT) technique was used for Doppler OCT imaging.

Laser cross-flow gas system

DOEpatents

Duncan, David B.

1992-01-01

A method and laser apparatus are disclosed which provide for a cross-flow of gas near one end of a laser discharge tube. The cross-flow of gas causes a concentration gradient which affects diffusion of contaminants in the discharge tube towards the cross-flow of the gas, which contaminants are then withdrawn from the discharge tube.

Small-spot laser-exposure effects on visual function

NASA Astrophysics Data System (ADS)

Zwick, Harry; Robbins, David O.; Stuck, Bruce E.; Lund, David J.; Reynolds, Scottie B.; Nawim, Maqsood; Schuschereba, Steven T.

1990-07-01

Laser field exposure effects on visual function involve produc tJon of minimal spot irradiation on or near the huntan fovea. Functional effects of such exposure may involve transient or perinanent change in visual function depending upon exposure dose. While Maximun Permissible Exposure (MPE) lirrtits define exposure in terins of threshold retinal niorphological change such limits are not applicable with regard to transient changes in visual function below MPE limits induced by alteration in retinal physiological processes. Mechanisms of transient and permanent functional change reported in these exper iments point out the need to examine laser safety limits in terms of both the functional as well as the morphological disturbance induced in retinal tissue. L

High Average Power Laser Gain Medium With Low Optical Distortion Using A Transverse Flowing Liquid Host

DOEpatents

Comaskey, Brian J.; Ault, Earl R.; Kuklo, Thomas C.

2005-07-05

A high average power, low optical distortion laser gain media is based on a flowing liquid media. A diode laser pumping device with tailored irradiance excites the laser active atom, ion or molecule within the liquid media. A laser active component of the liquid media exhibits energy storage times longer than or comparable to the thermal optical response time of the liquid. A circulation system that provides a closed loop for mixing and circulating the lasing liquid into and out of the optical cavity includes a pump, a diffuser, and a heat exchanger. A liquid flow gain cell includes flow straighteners and flow channel compression.

NASA low-speed centrifugal compressor for 3-D viscous code assessment and fundamental flow physics research

NASA Technical Reports Server (NTRS)

Hathaway, M. D.; Wood, J. R.; Wasserbauer, C. A.

1991-01-01

A low speed centrifugal compressor facility recently built by the NASA Lewis Research Center is described. The purpose of this facility is to obtain detailed flow field measurements for computational fluid dynamic code assessment and flow physics modeling in support of Army and NASA efforts to advance small gas turbine engine technology. The facility is heavily instrumented with pressure and temperature probes, both in the stationary and rotating frames of reference, and has provisions for flow visualization and laser velocimetry. The facility will accommodate rotational speeds to 2400 rpm and is rated at pressures to 1.25 atm. The initial compressor stage being tested is geometrically and dynamically representative of modern high-performance centrifugal compressor stages with the exception of Mach number levels. Preliminary experimental investigations of inlet and exit flow uniformly and measurement repeatability are presented. These results demonstrate the high quality of the data which may be expected from this facility. The significance of synergism between computational fluid dynamic analysis and experimentation throughout the development of the low speed centrifugal compressor facility is demonstrated.

Absorption Filter Based Optical Diagnostics in High Speed Flows

NASA Technical Reports Server (NTRS)

Samimy, Mo; Elliott, Gregory; Arnette, Stephen

1996-01-01

Two major regimes where laser light scattered by molecules or particles in a flow contains significant information about the flow are Mie scattering and Rayleigh scattering. Mie scattering is used to obtain only velocity information, while Rayleigh scattering can be used to measure both the velocity and the thermodynamic properties of the flow. Now, recently introduced (1990, 1991) absorption filter based diagnostic techniques have started a new era in flow visualization, simultaneous velocity and thermodynamic measurements, and planar velocity measurements. Using a filtered planar velocimetry (FPV) technique, we have modified the optically thick iodine filter profile of Miles, et al., and used it in the pressure-broaden regime which accommodates measurements in a wide range of velocity applications. Measuring velocity and thermodynamic properties simultaneously, using absorption filtered based Rayleigh scattering, involves not only the measurement of the Doppler shift, but also the spectral profile of the Rayleigh scattering signal. Using multiple observation angles, simultaneous measurement of one component velocity and thermodynamic properties in a supersonic jet were measured. Presently, the technique is being extended for simultaneous measurements of all three components of velocity and thermodynamic properties.

Laser Doppler imaging of genital blood flow: a direct measure of female sexual arousal.

PubMed

Waxman, Samantha E; Pukall, Caroline F

2009-08-01

Female sexual arousal is a challenging construct to measure, partly because of the subtle nature of its indicators, vaginal lubrication and genital swelling. As a result, many instruments have been used in an attempt to accurately measure it; however, problems are associated with each. Furthermore, the relationship between subjective and physiological indicators of arousal appears to be influenced by the instrument used to measure physiological arousal. Specifically, instruments measuring physiological arousal internally yield lower correlations between measures of physiological and subjective arousal than instruments examining the external genitals. Laser Doppler imaging (LDI) is a direct measure of external genital blood flow. The purpose of this study was to investigate the usefulness of LDI for measuring genital blood flow in women in response to erotic visual stimuli, and to explore the relationship between physiological and subjective sexual arousal. Sixty-five participants watched three 15-minute films during LDI scanning. Two nature films (measuring acclimatization and baseline blood flow levels) and one randomly assigned experimental film (erotic, anxiety, humor, or neutral) were used. Participants rated their level of subjective arousal following the third film. Results indicated a significant effect of film condition on genital blood flow, P < 0.001, with the erotic condition differing significantly from the other three conditions. In terms of the relationship between physiological and subjective sexual arousal, physiological arousal was significantly predicted by subjective ratings of sexual arousal (P < 0.001). LDI appears to be able to differentiate blood flow during erotic and nonerotic conditions. In addition, physiological sexual arousal was significantly predicted by women's reported subjective sexual arousal. These findings suggest that LDI is a useful instrument for measuring female sexual arousal, and that women may be more aware of their level of physiological arousal than previously assumed.

NASA low-speed centrifugal compressor for fundamental research

NASA Technical Reports Server (NTRS)

Wood, J. R.; Adam, P. W.; Buggele, A. E.

1983-01-01

A new centrifugal compressor facility being built by the NASA Lewis Research Center is described; its purpose is to obtain 'benchmark' experimental data for internal flow code verification and modeling. The facility will be heavily instrumented with standard pressure and temperature probes and have provisions for flow visualization and laser Doppler velocimetry. The facility will accommodate rotational speeds to 2400 rpm and will be rated at pressures to 1.25 atm. The initial compressor stage for testing is geometrically and dynamically representative of modern high-performance stages with the exception of Mach number levels. Design exit tip speed for the initial stage is 500 ft/sec with a pressure ratio of 1.17. The rotor exit backsweep is 55 deg from radial. The facility is expected to be operational in the first half of 1985.

Schlieren Cinematography of Current Driven Plasma Jet Dynamics

NASA Astrophysics Data System (ADS)

Loebner, Keith; Underwood, Thomas; Cappelli, Mark

2016-10-01

Schlieren cinematography of a pulsed plasma deflagration jet is presented and analyzed. An ultra-high frame rate CMOS camera coupled to a Z-type laser Schlieren apparatus is used to obtain flow-field refractometry data for the continuous flow Z-pinch formed within the plasma deflagration jet. The 10 MHz frame rate for 256 consecutive frames provides high temporal resolution, enabling turbulent fluctuations and plasma instabilities to be visualized over the course of a single pulse (20 μs). The Schlieren signal is radiometrically calibrated to obtain a two dimensional mapping of the refraction angle of the axisymmetric pinch plasma, and this mapping is then Abel inverted to derive the plasma density distribution as a function radius, axial coordinate, and time. Analyses of previously unknown discharge characteristics and comparisons with prior work are discussed.

Damage Evaluation Based on a Wave Energy Flow Map Using Multiple PZT Sensors

PubMed Central

Liu, Yaolu; Hu, Ning; Xu, Hong; Yuan, Weifeng; Yan, Cheng; Li, Yuan; Goda, Riu; Alamusi; Qiu, Jinhao; Ning, Huiming; Wu, Liangke

2014-01-01

A new wave energy flow (WEF) map concept was proposed in this work. Based on it, an improved technique incorporating the laser scanning method and Betti's reciprocal theorem was developed to evaluate the shape and size of damage as well as to realize visualization of wave propagation. In this technique, a simple signal processing algorithm was proposed to construct the WEF map when waves propagate through an inspection region, and multiple lead zirconate titanate (PZT) sensors were employed to improve inspection reliability. Various damages in aluminum and carbon fiber reinforced plastic laminated plates were experimentally and numerically evaluated to validate this technique. The results show that it can effectively evaluate the shape and size of damage from wave field variations around the damage in the WEF map. PMID:24463430

Monitoring skin microvascular dysfunction of type 1 diabetic mice using in vivo skin optical clearing

NASA Astrophysics Data System (ADS)

Feng, Wei; Shi, Rui; Zhu, Dan

2018-02-01

To monitor skin microvascular dysfunction of alloxan-induced type 1 diabetic mice model. In this work, we used laser speckle contrast imaging and hyperspectral imaging through in vivo skin optical clearing method to simultaneously monitor the noradrenaline-induced response of microvascular blood flow and blood oxygen with the development of diabetes. The main results showed that venous and arterious blood flow steadily decreased without recovery after injecting noradrenaline (NE), furthermore the influence of NE-induced arterious blood oxygen response greatly decreased, especially for 2-weeks and 4-weeks diabetic mice. This study demonstrated that skin microvascular function was a potential research biomarker for early warning in the occurrence and development of diabetes. And it provides a feasible solution to realize visualization of cutaneous microvessels for monitoring microvascular reactivity.

Comparison of DLK incidence after laser in situ keratomileusis associated with two femtosecond lasers: Femto LDV and IntraLase FS60

PubMed Central

Tomita, Minoru; Sotoyama, Yuko; Yukawa, Satoshi; Nakamura, Tadayuki

2013-01-01

Purpose To compare the incidence of diffuse lamellar keratitis (DLK) after laser in situ keratomileusis (LASIK) with flap creation using the Femto LDV and IntraLase™ FS60 femtosecond lasers.0 Methods A total of 818 consecutive myopic eyes had LASIK performed using either Femto LDV or IntraLase FS60 for flap creation. The same excimer laser, the Allegretto Wave® Eye-Q Laser, was used for correcting refractive errors for all patients. In the preoperative examination, uncorrected distance visual acuity, corrected distance visual acuity, and manifest refraction spherical equivalent were measured. At the postop examination, the same examinations were performed along with a slit-lamp biomicroscopic examination, and patients with DLK were classified into stages. For the statistical analysis of the DLK occurrence rate and the visual and refractive outcomes, the Mann-Whitney’s U-test was used. Results In the Femto LDV group with 514 eyes, 42 (8.17%) had DLK. In the IntraLase FS60 group with 304 eyes, 114 (37.5%) had DLK. There was a statistically significant difference in the DLK incidence rate between these groups (P < 0.0001). Both groups had excellent visual and refractive outcomes. Although low levels of DLK were observed for both groups, they did not affect visual acuity. Conclusion While there were significantly fewer incidences of low level DLK when using Femto LDV, neither femtosecond laser induced high levels of DLK, and any postoperative DLK cleared up within 1 week. Therefore, both lasers provide excellent results, with no clinical differences, and both excel at flap creation for LASIK. PMID:23874077

Laser cross-flow gas system

DOEpatents

Duncan, D.B.

1992-11-24

A method and laser apparatus are disclosed which provide for a cross-flow of gas near one end of a laser discharge tube. The cross-flow of gas causes a concentration gradient which affects diffusion of contaminants in the discharge tube towards the cross-flow of the gas, which contaminants are then withdrawn from the discharge tube. 1 figure.

Optical Coherence Tomography Angiography of Retinal Cavernous Hemangioma.

PubMed

Pierro, Luisa; Marchese, Alessandro; Gagliardi, Marco; Bandello, Francesco

2017-08-01

Retinal cavernous hemangioma is a rare, benign, retinal tumor characterized by angiomatous proliferation of vessels within the inner retina or the optic disc.1 Here we report a case of retinal cavernous hemangioma on the margin of the optic disc in the right eye of a 61-year-old asymptomatic female. The lesion was studied with multimodal imaging which included structural optical coherence tomography, fluorescein angiography, blue fundus auto-fluorescence, optical coherence tomography angiography (OCTA) (DRI OCT Triton; Topcon, Tokyo, Japan) and visual field examination. Blood circulation inside retinal cavernous hemangioma lesion is typically low-stagnant.2 However, OCTA demonstrated blood flow inside the lesion, illustrating its vascular circulation.3 Visual field was within the normal limits, except from a slight enlargement of the blind spot. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:684-685.]. Copyright 2017, SLACK Incorporated.

Application of a laser scanner to three dimensional visual sensing tasks

NASA Technical Reports Server (NTRS)

Ryan, Arthur M.

1992-01-01

The issues are described which are associated with using a laser scanner for visual sensing and the methods developed by the author to address them. A laser scanner is a device that controls the direction of a laser beam by deflecting it through a pair of orthogonal mirrors, the orientations of which are specified by a computer. If a calibrated laser scanner is combined with a calibrated camera, it is possible to perform three dimensional sensing by directing the laser at objects within the field of view of the camera. There are several issues associated with using a laser scanner for three dimensional visual sensing that must be addressed in order to use the laser scanner effectively. First, methods are needed to calibrate the laser scanner and estimate three dimensional points. Second, methods to estimate three dimensional points using a calibrated camera and laser scanner are required. Third, methods are required for locating the laser spot in a cluttered image. Fourth, mathematical models that predict the laser scanner's performance and provide structure for three dimensional data points are necessary. Several methods were developed to address each of these and has evaluated them to determine how and when they should be applied. The theoretical development, implementation, and results when used in a dual arm eighteen degree of freedom robotic system for space assembly is described.

Visualizing Time-Varying Phenomena In Numerical Simulations Of Unsteady Flows

NASA Technical Reports Server (NTRS)

Lane, David A.

1996-01-01

Streamlines, contour lines, vector plots, and volume slices (cutting planes) are commonly used for flow visualization. These techniques are sometimes referred to as instantaneous flow visualization techniques because calculations are based on an instant of the flowfield in time. Although instantaneous flow visualization techniques are effective for depicting phenomena in steady flows,they sometimes do not adequately depict time-varying phenomena in unsteady flows. Streaklines and timelines are effective visualization techniques for depicting vortex shedding, vortex breakdown, and shock waves in unsteady flows. These techniques are examples of time-dependent flow visualization techniques, which are based on many instants of the flowfields in time. This paper describes the algorithms for computing streaklines and timelines. Using numerically simulated unsteady flows, streaklines and timelines are compared with streamlines, contour lines, and vector plots. It is shown that streaklines and timelines reveal vortex shedding and vortex breakdown more clearly than instantaneous flow visualization techniques.

Scalar transport in inline mixers with spatially periodic flows

NASA Astrophysics Data System (ADS)

Baskan, Ozge; Rajaei, Hadi; Speetjens, Michel F. M.; Clercx, Herman J. H.

2017-01-01

Spatially persisting patterns form during the downstream evolution of passive scalars in three-dimensional (3D) spatially periodic flows due to the coupled effect of stretching and folding mechanisms of the flow field. This has been investigated in many computational and theoretical studies of 2D time-periodic and 3D spatially periodic flow fields. However, experimental studies, to date, have mainly focused on flow visualization with streaks of dye rather than fully 3D scalar field measurements. Our study employs 3D particle tracking velocimetry and 3D laser-induced fluorescence to analyze the evolution of 3D flow and scalar fields and the correlation between the coherent flow/scalar field structures in a representative inline mixer, the Quatro static mixer. For this purpose an experimental setup that consists of an optically accessible test section with transparent internal elements accommodating a pressure-driven pipe flow has been built. The flow and scalar fields clearly underline the complementarity of the experimental results with numerical simulations and provide validation of the periodicity assumption needed in numerical studies. The experimental procedure employed in this investigation, which allows studying the scalar transport in the advective limit, demonstrates the suitability of the present method for exploratory mixing studies of a variety of mixing devices, beyond the Quatro static mixer.

Two-dimensional interferometric Rayleigh scattering velocimetry using multibeam probe laser

NASA Astrophysics Data System (ADS)

Sheng, Wang; Jin-Hai, Si; Jun, Shao; Zhi-yun, Hu; Jing-feng, Ye; Jing-Ru, Liu

2017-11-01

In order to achieve the two-dimensional (2-D) velocity measurement of a flow field at extreme condition, a 2-D interferometric Rayleigh scattering (IRS) velocimetry using a multibeam probe laser was developed. The method using a multibeam probe laser can record the reference interference signal and the flow interference signal simultaneously. What is more, this method can solve the problem of signal overlap using the laser sheet detection method. The 2-D IRS measurement system was set up with a multibeam probe laser, aspherical lens collection optics, and a solid Fabry-Perot etalon. A multibeam probe laser with 0.5-mm intervals was formed by collimating a laser sheet passing through a cylindrical microlens arrays. The aspherical lens was used to enhance the intensity of the Rayleigh scattering signal. The 2-D velocity field results of a Mach 1.5 air flow were obtained. The velocity in the flow center is about 450 m/s. The reconstructed results fit well with the characteristic of flow, which indicate the validity of this technique.

Function-based design process for an intelligent ground vehicle vision system

NASA Astrophysics Data System (ADS)

Nagel, Robert L.; Perry, Kenneth L.; Stone, Robert B.; McAdams, Daniel A.

2010-10-01

An engineering design framework for an autonomous ground vehicle vision system is discussed. We present both the conceptual and physical design by following the design process, development and testing of an intelligent ground vehicle vision system constructed for the 2008 Intelligent Ground Vehicle Competition. During conceptual design, the requirements for the vision system are explored via functional and process analysis considering the flows into the vehicle and the transformations of those flows. The conceptual design phase concludes with a vision system design that is modular in both hardware and software and is based on a laser range finder and camera for visual perception. During physical design, prototypes are developed and tested independently, following the modular interfaces identified during conceptual design. Prototype models, once functional, are implemented into the final design. The final vision system design uses a ray-casting algorithm to process camera and laser range finder data and identify potential paths. The ray-casting algorithm is a single thread of the robot's multithreaded application. Other threads control motion, provide feedback, and process sensory data. Once integrated, both hardware and software testing are performed on the robot. We discuss the robot's performance and the lessons learned.

Effect of Different Ground Scenarios on Flow Structure of a Rotor At Hover Condition

NASA Astrophysics Data System (ADS)

Kocak, Goktug; Nalbantoglu, Volkan; Yavuz, Mehmet Metin

2017-11-01

The ground effect of a scaled model rotor at hover condition was investigated experimentally in a confined environment. Different ground effect scenarios including full, partial, and inclined conditions, compared to out of ground condition, were characterized qualitatively and quantitatively using laser illuminated smoke visualization and Laser Doppler Anemometry measurements. The results indicate that the presence of the ground affects the flow regime near the blade tip by changing the spatial extent and the path of the vortex core. After the impingement of the wake to the ground, highly unsteady and turbulent wake is observed. Both the mean and the root mean square of the induced velocity increase toward the blade tip. In line with this, the spectral power of the dominant frequency in the velocity fluctuations significantly increases toward the blade tip. All these observations are witnessed in all ground effect conditions tested in the present study. Considering the inclined ground effect in particular, it is observed that the mean induced velocities of the high side (mountain) are higher compared to the velocities of the low side (valley) in contrast to the general trend observed in the present study where the ground effect reduces the induced velocity.

Fluorescence Imaging of Underexpanded Jets and Comparison with CFD

NASA Technical Reports Server (NTRS)

Wilkes, Jennifer A.; Glass, Christopher E.; Danehy, Paul M.; Nowak, Robert J.

2006-01-01

An experimental study of underexpanded and highly underexpanded axisymmetric nitrogen free jets seeded with 0.5% nitric oxide (NO) and issuing from a sonic orifice was conducted at NASA Langley Research Center. Reynolds numbers based on nozzle exit conditions ranged from 770 to 35,700, and nozzle exit-to-ambient jet pressure ratios ranged from 2 to 35. These flows were non-intrusively visualized with a spatial resolution of approximately 0.14 mm x 0.14 mm x 1 mm thick and a temporal resolution of 1 s using planar laser-induced fluorescence (PLIF) of NO, with the laser tuned to the strongly-fluorescing UV absorption bands of the Q1 band head near 226.256 nm. Three laminar cases were selected for comparison with computational fluid dynamics (CFD). The cases were run using GASP (General Aerodynamic Simulation Program) Version 4. Comparisons of the fundamental wavelength of the jet flow showed good agreement between CFD and experiment for all three test cases, while comparisons of Mach disk location and Mach disk diameter showed good agreement at lower jet pressure ratios, with a tendency to slightly underpredict these parameters with increasing jet pressure ratio.

In-flight imaging of transverse gas jets injected into transonic and supersonic crossflows: Design and development. M.S. Thesis, Mar. 1993

NASA Technical Reports Server (NTRS)

Wang, Kon-Sheng Charles

1994-01-01

The design and development of an airborne flight-test experiment to study nonreacting gas jets injected transversely into transonic and supersonic crossflows is presented. Free-stream/crossflow Mach numbers range from 0.8 to 2.0. Planar laser-induced fluorescence (PLIF) of an iodine-seeded nitrogen jet is used to visualize the jet flow. Time-dependent images are obtained with a high-speed intensified video camera synchronized to the laser pulse rate. The entire experimental assembly is configured compactly inside a unique flight-test-fixture (FTF) mounted under the fuselage of the F-104G research aircraft, which serves as a 'flying wind tunnel' at NASA Dryden Flight Research Center. The aircraft is flown at predetermined speeds and altitudes to permit a perfectly expanded (or slightly underexpanded) gas jet to form just outside the FTF at each free-stream Mach number. Recorded gas jet images are then digitized to allow analysis of jet trajectory, spreading, and mixing characteristics. Comparisons will be made with analytical and numerical predictions. This study shows the viability of applying highly sophisticated groundbased flow diagnostic techniques to flight-test vehicle platforms that can achieve a wide range of thermo/fluid dynamic conditions. Realistic flow environments, high enthalpies, unconstrained flowfields, and moderate operating costs are also realized, in contrast to traditional wind-tunnel testing.

Ergodic theory and experimental visualization of chaos in 3D flows

NASA Astrophysics Data System (ADS)

Sotiropoulos, Fotis; Mezic, Igor

2000-11-01

In his motivation for the ergodic hypothesis Gibbs invoked an analogy with fluid mixing: “…Yet no fact is more familiar to us than that stirring tends to bring a liquid to a state of uniform mixture, or uniform densities of its components…”. Although proof of the ergodic hypothesis is possible only for the simplest of systems using methods from ergodic theory, the use of the hypothesis has led to many accurate predictions in statistical mechanics. The problem of fluid mixing, however, turned out to be considerably more complicated than Gibbs envisioned. Chaotic advection can indeed lead to efficient mixing even in non-turbulent flows, but many non-mixed islands are known to persist within well-mixed regions. In numerical studies, Poincaré maps can be used to reveal the structure of such islands but their visualization in the laboratory requires laborious experimental procedures and is possible only for certain types of flows. Here we propose the first non-intrusive, simple to implement, and generally applicable technique for constructing experimental Poincaré maps and apply it to a steady, 3D, vortex breakdown bubble. We employ standard laser-induced fluorescence (LIF) and construct Poincaré maps by time averaging a sufficiently long sequence of instantaneous LIF images. We also show that ergodic theory methods provide a rigorous theoretical justification for this approach whose main objective is to reveal the non-ergodic regions of the flow.

1984 AFOSR Research Meeting on Diagnostics of Reacting Flow Held at New Haven, Connecticut on 21-22 March 1984.

DTIC Science & Technology

1984-02-01

EXCIPLEX SYSTEMS FOR REAL-TIME VISUALIZATION OF FUEL SPRAYS. Lynn Melton, University of Texas at Dallas, Dallas, TX - 1620 11 LASER EXCITED...SIZING BY MEASUREMENT OF BROWNIAN MOTION. Alan * Stanton and Wal Cheng, Aerodyne Research, Inc, Bilerlica, MA (New Start) 1530 Break* 1550 10 EXCIPLEX ...0! CD 14 w L4JJ -V4 4--4 W 4-I,4 ’V 4W Co -S 04-1 ~4 0 .E- > * J~NJUIHJfl3o A AONMflO3C4 4 ** 1984 DIAGNOSTICS MEETING ** Abstract 10 Pg I EXCIPLEX

Investigation of rotor blade element airloads for a teetering rotor in the blade stall regime (second wind tunnel test)

NASA Technical Reports Server (NTRS)

Dadone, L. U.; Fukushima, T.

1975-01-01

A test was conducted in the NASA-Ames 7 x 10 ft low speed wind tunnel on a seven-foot diameter model of a teetering rotor. The objectives of the test were: (1) acquire pressure data for correlation with laser and flow visualization measurements; (2) explore rotor propulsive force limits by varying the advance ratio at constant lift and propulsive force coefficients; (3) obtain additional data to define the differences between teetering and articulated rotors; and (4) verify the acceleration sensitivity of experimental transducers. Results are presented.

Alternative Bio-Derived JP-8 Class Fuel and JP-8 Fuel: Flame Tube Combustor Test Results Compared using a GE TAPS Injector Configuration

NASA Technical Reports Server (NTRS)

Hicks, Yolanda R.; Anderson, Robert; Tedder, Sarah

2016-01-01

This paper presents results from tests in a NASA Glenn Research Center (GRC) flame tube facility, where a bio-derived alternate fuel was compared with JP-8 for emissions and general combustion performance. A research version of General Electric Aviation (GE) TAPS injector was used for the tests. Results include 2D, planar laser-based imaging as well as basic flow visualization of the flame. Four conditions were selected that simulate various engine power conditions relevant to NASA Fundamental Aeronautics Supersonics and Environmentally Responsible Aviation Projects were tested.

Interaction of gusts with forest edges

NASA Astrophysics Data System (ADS)

Ruck, Bodo; Tischmacher, Michael

2012-05-01

Experimental investigations in an atmospheric boundary layer wind tunnel were carried out in order to study the interaction of gusts with forest edges. Summarizing the state of knowledge in the field of forest damages generated by extreme storms, there is a strong indication that in many cases, windthrow of trees starts near the forest edge from where it spreads into the stand. The high-transient interaction between gusts and (porous) forest edges produce unsteady flow phenomena not known so far. From a fluid mechanical point of view, the flow type resembles a forward-facing porous step flow, which is significantly influenced by the characteristics of the oncoming atmospheric boundary layer flow and the shape and `porous properties' of the forest edge. The paper reports systematic investigations on the interaction of artificially generated gusts and forest edge models in an atmospheric boundary layer wind tunnel. The experimental investigations were carried out with a laser-based time-resolved PIV-system and high speed photography. Different flow phenomena like gust streching, vortex formation, Kelvin-Helmholtz instabilities or wake production of turbulence could be measured or visualized contributing to the understanding of the complex flow perfomance over the forest edge.

Off-surface infrared flow visualization

NASA Technical Reports Server (NTRS)

Manuel, Gregory S. (Inventor); Obara, Clifford J. (Inventor); Daryabeigi, Kamran (Inventor); Alderfer, David W. (Inventor)

1993-01-01

A method for visualizing off-surface flows is provided. The method consists of releasing a gas with infrared absorbing and emitting characteristics into a fluid flow and imaging the flow with an infrared imaging system. This method allows for visualization of off-surface fluid flow in-flight. The novelty of this method is found in providing an apparatus for flow visualization which is contained within the aircraft so as not to disrupt the airflow around the aircraft, is effective at various speeds and altitudes, and is longer-lasting than previous methods of flow visualization.

LDV Surveys Over a Fighter Model at Moderate to High Angles of Attack

NASA Technical Reports Server (NTRS)

Sellers, William L., III; Meyers, James F.; Hepner, Timothy E.

2004-01-01

The vortex flowfield over an advanced twin-tailed fighter configuration was measured in a low-speed wind tunnel at two angles of attack. The primary test data consisted of 3-component velocity surveys obtained using a Laser Doppler Velocimeter. Laser light sheet and surface flow visualization were also obtained to provide insight into the flowfield structure. Time-averaged velocities and the root mean square of the velocity fluctuations were obtained at two cross-sections above the model. At 15 degrees angle of attack, the vortices generated by the wing leading edge extension (LEX) were unburst over the model and passed outboard of the vertical tail. At 25 degrees angle of attack, the vortices burst in the vicinity of the wing-LEX intersection and impact directly on the vertical tails. The RMS levels of the velocity fluctuations reach values of approximately 30% in the region of the vertical tails.

Eye injuries from laser exposure: a review.

PubMed

Hudson, S J

1998-05-01

Lasers pose a significant threat to vision in modern military operations. Anti-personnel lasers have been designed that can cause intentional blindness in large numbers of personnel. Although the use of blinding laser weapons during combat has been prohibited by international legislation, research and development of these weapons have not been prohibited, and significant controversy remains. Unintentional blinding can also result from other types of lasers used on the battlefield, such as range-finders and anti-material lasers. Lasers that are capable of producing blindness operate within specific wavelength parameters and include visible and near infrared lasers. Patients who suffer from laser eye injuries usually complain of flash blindness, followed by transient or permanent visual loss. Laser retinal damage should be suspected in any patient with visual complaints in an operational setting. The treatment for laser retinal injuries is extremely limited, and prevention is essential. Improved protective eyeware and other countermeasures to laser eye injury are necessary as long as the threat remains.

Supercontinuum white light lasers for flow cytometry

PubMed Central

Telford, William G.; Subach, Fedor V.; Verkhusha, Vladislav V.

2009-01-01

Excitation of fluorescent probes for flow cytometry has traditionally been limited to a few discrete laser lines, an inherent limitation in our ability to excite the vast array of fluorescent probes available for cellular analysis. In this report, we have used a supercontinuum (SC) white light laser as an excitation source for flow cytometry. By selectively filtering the wavelength of interest, almost any laser wavelength in the visible spectrum can be separated and used for flow cytometric analysis. The white light lasers used in this study were integrated into a commercial flow cytometry platform, and a series of high-transmission bandpass filters used to select wavelength ranges from the blue (~480 nm) to the long red (>700 nm). Cells labeled with a variety of fluorescent probes or expressing fluorescent proteins were then analyzed, in comparison with traditional lasers emitting at wavelengths similar to the filtered SC source. Based on a standard sensitivity metric, the white light laser bandwidths produced similar excitation levels to traditional lasers for a wide variety of fluorescent probes and expressible proteins. Sensitivity assessment using fluorescent bead arrays confirmed that the SC laser and traditional sources resulted in similar levels of detection sensitivity. Supercontinuum white light laser sources therefore have the potential to remove a significant barrier in flow cytometric analysis, namely the limitation of excitation wavelengths. Almost any visible wavelength range can be made available for excitation, allowing access to virtually any fluorescent probe, and permitting “fine-tuning” of excitation wavelength to particular probes. PMID:19072836

COMPARISON OF RETINAL PATHOLOGY VISUALIZATION IN MULTISPECTRAL SCANNING LASER IMAGING.

PubMed

Meshi, Amit; Lin, Tiezhu; Dans, Kunny; Chen, Kevin C; Amador, Manuel; Hasenstab, Kyle; Muftuoglu, Ilkay Kilic; Nudleman, Eric; Chao, Daniel; Bartsch, Dirk-Uwe; Freeman, William R

2018-03-16

To compare retinal pathology visualization in multispectral scanning laser ophthalmoscope imaging between the Spectralis and Optos devices. This retrospective cross-sectional study included 42 eyes from 30 patients with age-related macular degeneration (19 eyes), diabetic retinopathy (10 eyes), and epiretinal membrane (13 eyes). All patients underwent retinal imaging with a color fundus camera (broad-spectrum white light), the Spectralis HRA-2 system (3-color monochromatic lasers), and the Optos P200 system (2-color monochromatic lasers). The Optos image was cropped to a similar size as the Spectralis image. Seven masked graders marked retinal pathologies in each image within a 5 × 5 grid that included the macula. The average area with detected retinal pathology in all eyes was larger in the Spectralis images compared with Optos images (32.4% larger, P < 0.0001), mainly because of better visualization of epiretinal membrane and retinal hemorrhage. The average detection rate of age-related macular degeneration and diabetic retinopathy pathologies was similar across the three modalities, whereas epiretinal membrane detection rate was significantly higher in the Spectralis images. Spectralis tricolor multispectral scanning laser ophthalmoscope imaging had higher rate of pathology detection primarily because of better epiretinal membrane and retinal hemorrhage visualization compared with Optos bicolor multispectral scanning laser ophthalmoscope imaging.

Experimental studying of local characteristics of gas-liquid flow in microchannels by optical methods

NASA Astrophysics Data System (ADS)

Bartkus, German V.; Kuznetsov, Vladimir V.

2018-03-01

The local characteristics of the gas-liquid two-phase flow in rectangular microchannels 420 × 280 μm and 395 × 205 μm with T-shaped mixer inlet were experimentally investigated in this work. Visualization of flow regimes and measurement of local characteristics were carried out using a high-speed video camera Optronis CX600x2 and laser-induced fluorescence (LIF) method. Deionized water and ethanol were used as the liquid phase, and nitrogen - as the gas phase. The Rhodamine 6G dye was added to the liquid. The location of the microchannel in space (horizontal, vertical) was changed. The profiles of the liquid film along the long side of the microchannel were obtained, the local film thickness was measured in the channel`s central section for the elongated bubble flow and the transition flow of the deionized water-nitrogen mixture. The unevenness of liquid film thickness at the channel cross-section and along the bubble was experimentally shown. The temporal dynamics of two-phase flow for the ethanol-nitrogen mixture was shown. It was found that most of the liquid flows in the meniscus on the short side of the microchannel for the present gas and liquid flow rates.

Dynamic features of bubble induced by a nanosecond pulse laser in still and flowing water

NASA Astrophysics Data System (ADS)

Charee, Wisan; Tangwarodomnukun, Viboon

2018-03-01

Underwater laser ablation techniques have been developed and employed to synthesis nanoparticles, to texture workpiece surface and to assist the material removal in laser machining process. However, the understanding of laser-material-water interactions, bubble formation and effects of water flow on ablation performance has still been very limited. This paper thus aims at exploring the formation and collapse of bubbles during the laser ablation of silicon in water. The effects of water flow rate on bubble formation and its consequences to the laser disturbance and cut features obtained in silicon were observed by using a high speed camera. A nanosecond pulse laser emitting the laser pulse energy of 0.2-0.5 mJ was employed in the experiment. The results showed that the bubble size was found to increase with the laser pulse energy. The use of high water flow rate can importantly facilitate the ejection of ablated particles from the workpiece surface, hence resulting in less deposition to the work surface and minimizing any disturbance to the laser beam during the ablation in water. Furthermore, a clean micro-groove in silicon wafer can successfully be produced when the process was performed in the high water flow rate condition. The findings of this study could provide an essential guideline for process selection, control and improvement in the laser micro-/submicro-fabrication using the underwater technique.

Velocimetry using scintillation of a laser beam for a laser-based gas-flux monitor

NASA Astrophysics Data System (ADS)

Kagawa, Naoki; Wada, Osami; Koga, Ryuji

1999-05-01

This paper describes a velocimetry system using scintillation of a laser-beam with spatial filters based on sensor arrays for a laser- based gas flux monitor. In the eddy correlation method, gas flux is obtained by mutual relation between the gas density and the flow velocity. The velocimetry system is developed to support the flow velocity monitor portion of the laser-based gas flux monitor with a long span for measurement. In order to sense not only the flow velocity but also the flow direction, two photo diode arrays are arranged with difference of a quarter period of the weighting function between them; the two output signals from the sensor arrays have phase difference of either (pi) /2 or -(pi) /2 depending on the sense of flow direction. In order to obtain the flow velocity and the flow direction instantly, an electronic apparatus built by the authors extracts frequency and phase from crude outputs of the pair of sensors. A feasibility of the velocimetry was confirmed indoors by measurement of the flow- velocity vector of the convection. Measured flow-velocity vector of the upward flow agreed comparatively with results of an ultrasonic anemometer.

Needle tip visualization by bevel-point ultrasound generator and prototype photoacoustic imaging system

NASA Astrophysics Data System (ADS)

Irisawa, Kaku; Murakoshi, Dai; Hashimoto, Atsushi; Yamamoto, Katsuya; Hayakawa, Toshiro

2017-03-01

Visualization of the tip of medical devices like needles or catheters under ultrasound imaging has been a continuous topic since the early 1980's. In this study, a needle tip visualization system utilizing photoacoustic effects is proposed. In order to visualize the needle tip, an optical fiber was inserted into a needle. The optical fiber tip is placed on the needle bevel and affixed with black glue. The pulsed laser light from laser diode was transferred to the optical fiber and converted to ultrasound due to laser light absorption of the black glue and the subsequent photoacoustic effect. The ultrasound is detected by transducer array and reconstructed into photoacoustic images in the ultrasound unit. The photoacoustic image is displayed with a superposed ultrasound B-mode image. As a system evaluation, the needle is punctured into bovine meat and the needle tip is observed with commercialized conventional linear transducers or convex transducers. The needle tip is visualized clearly at 7 and 12 cm depths with linear and convex probes, respectively, even with a steep needle puncture angle of around 90 degrees. Laser and acoustic outputs, and thermal rise at the needle tip, were measured and were well below the limits of the safety standards. Compared with existing needle tip visualization technologies, the photoacoustic needle tip visualization system has potential distinguishable features for clinical procedures related with needle puncture and injection.

A collection of flow visualization techniques used in the Aerodynamic Research Branch

NASA Technical Reports Server (NTRS)

1984-01-01

Theoretical and experimental research on unsteady aerodynamic flows is discussed. Complex flow fields that involve separations, vortex interactions, and transonic flow effects were investigated. Flow visualization techniques are used to obtain a global picture of the flow phenomena before detailed quantitative studies are undertaken. A wide variety of methods are used to visualize fluid flow and a sampling of these methods is presented. It is emphasized that the visualization technique is a thorough quantitative analysis and subsequent physical understanding of these flow fields.

Spatio-Temporal Modelling of Dust Transport over Surface Mining Areas and Neighbouring Residential Zones.

PubMed

Matejicek, Lubos; Janour, Zbynek; Benes, Ludek; Bodnar, Tomas; Gulikova, Eva

2008-06-06

Projects focusing on spatio-temporal modelling of the living environment need to manage a wide range of terrain measurements, existing spatial data, time series, results of spatial analysis and inputs/outputs from numerical simulations. Thus, GISs are often used to manage data from remote sensors, to provide advanced spatial analysis and to integrate numerical models. In order to demonstrate the integration of spatial data, time series and methods in the framework of the GIS, we present a case study focused on the modelling of dust transport over a surface coal mining area, exploring spatial data from 3D laser scanners, GPS measurements, aerial images, time series of meteorological observations, inputs/outputs form numerical models and existing geographic resources. To achieve this, digital terrain models, layers including GPS thematic mapping, and scenes with simulation of wind flows are created to visualize and interpret coal dust transport over the mine area and a neighbouring residential zone. A temporary coal storage and sorting site, located near the residential zone, is one of the dominant sources of emissions. Using numerical simulations, the possible effects of wind flows are observed over the surface, modified by natural objects and man-made obstacles. The coal dust drifts with the wind in the direction of the residential zone and is partially deposited in this area. The simultaneous display of the digital map layers together with the location of the dominant emission source, wind flows and protected areas enables a risk assessment of the dust deposition in the area of interest to be performed. In order to obtain a more accurate simulation of wind flows over the temporary storage and sorting site, 3D laser scanning and GPS thematic mapping are used to create a more detailed digital terrain model. Thus, visualization of wind flows over the area of interest combined with 3D map layers enables the exploration of the processes of coal dust deposition at a local scale. In general, this project could be used as a template for dust-transport modelling which couples spatial data focused on the construction of digital terrain models and thematic mapping with data generated by numerical simulations based on Reynolds averaged Navier-Stokes equations.

Spatio-Temporal Modelling of Dust Transport over Surface Mining Areas and Neighbouring Residential Zones

PubMed Central

Matejicek, Lubos; Janour, Zbynek; Benes, Ludek; Bodnar, Tomas; Gulikova, Eva

2008-01-01

Projects focusing on spatio-temporal modelling of the living environment need to manage a wide range of terrain measurements, existing spatial data, time series, results of spatial analysis and inputs/outputs from numerical simulations. Thus, GISs are often used to manage data from remote sensors, to provide advanced spatial analysis and to integrate numerical models. In order to demonstrate the integration of spatial data, time series and methods in the framework of the GIS, we present a case study focused on the modelling of dust transport over a surface coal mining area, exploring spatial data from 3D laser scanners, GPS measurements, aerial images, time series of meteorological observations, inputs/outputs form numerical models and existing geographic resources. To achieve this, digital terrain models, layers including GPS thematic mapping, and scenes with simulation of wind flows are created to visualize and interpret coal dust transport over the mine area and a neighbouring residential zone. A temporary coal storage and sorting site, located near the residential zone, is one of the dominant sources of emissions. Using numerical simulations, the possible effects of wind flows are observed over the surface, modified by natural objects and man-made obstacles. The coal dust drifts with the wind in the direction of the residential zone and is partially deposited in this area. The simultaneous display of the digital map layers together with the location of the dominant emission source, wind flows and protected areas enables a risk assessment of the dust deposition in the area of interest to be performed. In order to obtain a more accurate simulation of wind flows over the temporary storage and sorting site, 3D laser scanning and GPS thematic mapping are used to create a more detailed digital terrain model. Thus, visualization of wind flows over the area of interest combined with 3D map layers enables the exploration of the processes of coal dust deposition at a local scale. In general, this project could be used as a template for dust-transport modelling which couples spatial data focused on the construction of digital terrain models and thematic mapping with data generated by numerical simulations based on Reynolds averaged Navier-Stokes equations. PMID:27879911

Aircrew laser eye protection: visual consequences and mission performance.

PubMed

Thomas, S R

1994-05-01

Battlefield laser proliferation poses a mounting risk to aircrew and ground personnel. Laser eye protection (LEP) based on current mature, mass-producible technologies absorbs visible light and can impact visual performance and color identification. These visual consequences account for many of the mission incompatibilities associated with LEP. Laboratory experiments and field investigations that examined the effects of LEP on visual performance and mission compatibility are reviewed. Laboratory experiments assessed the ability of subjects to correctly read and identify the color of head-down display symbology and tactical pilotage charts (TPC's) with three prototype LEP visors. Field investigations included Weapons Systems Trainer (WST), ground, and flight tests of the LEP visors. Recommendations for modifying aviation lighting systems to improve LEP compatibility are proposed. Issues concerning flight safety when using LEP during air operation are discussed.

The Relationship between OCT-measured Central Retinal Thickness and Visual Acuity in Diabetic Macular Edema

PubMed Central

2008-01-01

Objective To compare optical coherence tomography (OCT)-measured retinal thickness and visual acuity in eyes with diabetic macular edema (DME) both before and after macular laser photocoagulation. Design Cross-sectional and longitudinal study. Participants 210 subjects (251 eyes) with DME enrolled in a randomized clinical trial of laser techniques. Methods Retinal thickness was measured with OCT and visual acuity was measured with the electronic-ETDRS procedure. Main Outcome Measures OCT-measured center point thickness and visual acuity Results The correlation coefficients for visual acuity versus OCT center point thickness were 0.52 at baseline and 0.49, 0.36, and 0.38 at 3.5, 8, and 12 months post-laser photocoagulation. The slope of the best fit line to the baseline data was approximately 4.4 letters (95% C.I.: 3.5, 5.3) better visual acuity for every 100 microns decrease in center point thickness at baseline with no important difference at follow-up visits. Approximately one-third of the variation in visual acuity could be predicted by a linear regression model that incorporated OCT center point thickness, age, hemoglobin A1C, and severity of fluorescein leakage in the center and inner subfields. The correlation between change in visual acuity and change in OCT center point thickening 3.5 months after laser treatment was 0.44 with no important difference at the other follow-up times. A subset of eyes showed paradoxical improvements in visual acuity with increased center point thickening (7–17% at the three time points) or paradoxical worsening of visual acuity with a decrease in center point thickening (18%–26% at the three time points). Conclusions There is modest correlation between OCT-measured center point thickness and visual acuity, and modest correlation of changes in retinal thickening and visual acuity following focal laser treatment for DME. However, a wide range of visual acuity may be observed for a given degree of retinal edema and paradoxical increases in center point thickening with increases in visual acuity as well as paradoxical decreases in center point thickening with decreases in visual acuity were not uncommon. Thus, although OCT measurements of retinal thickness represent an important tool in clinical evaluation, they cannot reliably substitute as a surrogate for visual acuity at a given point in time. This study does not address whether short-term changes on OCT are predictive of long-term effects on visual acuity. PMID:17123615

Three dimensional laser Doppler velocimeter turbulence measurements in a pipe flow

NASA Technical Reports Server (NTRS)

Fuller, C. E., III; Cliff, W. C.; Huffaker, R. M.

1973-01-01

The mean and turbulent u, v, and w components of a gaseous fully developed turbulent pipe flow were measured with a laser Doppler velocimeter system. Measurements of important system parameters are presented and discussed in relation to the measurement accuracy. Simultaneous comparisons of the laser Doppler and hot wire anemometer measurements in the turbulent flow provided evidence that the two systems were responding to the same flow phenomena.

Software Aids Visualization of Computed Unsteady Flow

NASA Technical Reports Server (NTRS)

Kao, David; Kenwright, David

2003-01-01

Unsteady Flow Analysis Toolkit (UFAT) is a computer program that synthesizes motions of time-dependent flows represented by very large sets of data generated in computational fluid dynamics simulations. Prior to the development of UFAT, it was necessary to rely on static, single-snapshot depictions of time-dependent flows generated by flow-visualization software designed for steady flows. Whereas it typically takes weeks to analyze the results of a largescale unsteady-flow simulation by use of steady-flow visualization software, the analysis time is reduced to hours when UFAT is used. UFAT can be used to generate graphical objects of flow visualization results using multi-block curvilinear grids in the format of a previously developed NASA data-visualization program, PLOT3D. These graphical objects can be rendered using FAST, another popular flow visualization software developed at NASA. Flow-visualization techniques that can be exploited by use of UFAT include time-dependent tracking of particles, detection of vortex cores, extractions of stream ribbons and surfaces, and tetrahedral decomposition for optimal particle tracking. Unique computational features of UFAT include capabilities for automatic (batch) processing, restart, memory mapping, and parallel processing. These capabilities significantly reduce analysis time and storage requirements, relative to those of prior flow-visualization software. UFAT can be executed on a variety of supercomputers.

Laser-based investigations in gas turbine model combustors

NASA Astrophysics Data System (ADS)

Meier, W.; Boxx, I.; Stöhr, M.; Carter, C. D.

2010-10-01

Dynamic processes in gas turbine (GT) combustors play a key role in flame stabilization and extinction, combustion instabilities and pollutant formation, and present a challenge for experimental as well as numerical investigations. These phenomena were investigated in two gas turbine model combustors for premixed and partially premixed CH4/air swirl flames at atmospheric pressure. Optical access through large quartz windows enabled the application of laser Raman scattering, planar laser-induced fluorescence (PLIF) of OH, particle image velocimetry (PIV) at repetition rates up to 10 kHz and the simultaneous application of OH PLIF and PIV at a repetition rate of 5 kHz. Effects of unmixedness and reaction progress in lean premixed GT flames were revealed and quantified by Raman scattering. In a thermo-acoustically unstable flame, the cyclic variation in mixture fraction and its role for the feedback mechanism of the instability are addressed. In a partially premixed oscillating swirl flame, the cyclic variations of the heat release and the flow field were characterized by chemiluminescence imaging and PIV, respectively. Using phase-correlated Raman scattering measurements, significant phase-dependent variations of the mixture fraction and fuel distributions were revealed. The flame structures and the shape of the reaction zones were visualized by planar imaging of OH distribution. The simultaneous OH PLIF/PIV high-speed measurements revealed the time history of the flow field-flame interaction and demonstrated the development of a local flame extinction event. Further, the influence of a precessing vortex core on the flame topology and its dynamics is discussed.

High-Spatial-Resolution OH PLIF Visualization in a Cavity-Stabilized Ethylene-Air Turbulent Flame

NASA Technical Reports Server (NTRS)

Geipel, Clayton M.; Rockwell, Robert D.; Chelliah, Harsha K.; Cutler, Andrew D.; Spelker, Christopher A.; Hashem, Zeid; Danehy, Paul M.

2017-01-01

High-spatial-resolution OH planar laser-induced fluorescence was measured for a premixed ethylene-air turbulent flame in an electrically-heated Mach 2 continuous-flow facility (University of Virginia Supersonic Combustion Facility, Configuration E.) The facility comprised a Mach 2 nozzle, an isolator with flush-wall fuel injectors, a combustor with optical access, and an extender. The flame was anchored at a cavity flameholder with a backward-facing step of height 9 mm. The temperature-insensitive Q1(8) transition of OH was excited using laser light of wavelength 283.55 nm. A spatial filter was used to create a laser sheet approximately 25 microns thick based on full-width at half maximum (FWHM). Extension tubes increased the magnification of an intensified camera system, achieving in-plane resolution of 40 microns based on a 50% modulation transfer function (MTF). The facility was tested with total temperature 1200 K, total pressure 300 kPa, local fuel/air equivalence ratios of approximately 0.4, and local Mach number of approximately 0.73 in the combustor. A test case with reduced total temperature and another with reduced equivalence ratio were also tested. PLIF images were acquired along a streamwise plane bisecting the cavity flameholder, from the backward facing step to 120 mm downstream of the step. The smallest observed features in the flow had width of approximately 110 microns. Flame surface density was calculated for OH PLIF images.

Effect of Er,Cr:YSGG laser on human dentin fluid flow.

PubMed

Al-Omari, Wael M; Palamara, Joseph E

2013-11-01

The aim of the current investigation was to assess the rate and magnitude of dentin fluid flow of dentinal surfaces irradiated with Er,Cr:YSGG laser. Twenty extracted third molars were sectioned, mounted, and irradiated with Er,Cr:YSGG laser at 3.5 and 4.5 W power settings. Specimens were connected to an automated fluid flow measurement apparatus (Flodec). The rate, magnitude, and direction of dentin fluid flow were recorded at baseline and after irradiation. Nonparametric Wilcoxon signed ranks repeated measure t test revealed a statistically significant reduction in fluid flow for all the power settings. The 4.5-W power output reduced the flow significantly more than the 3.5 W. The samples showed a baseline outward flow followed by inward flow due to irradiation then followed by decreased outward flow. It was concluded that Er,Cr:YSGG laser irradiation at 3.5 and 4.5 W significantly reduced dentinal fluid flow rate. The reduction was directly proportional to power output.

Effect of anterior capsule contraction on visual function after cataract surgery.

PubMed

Hayashi, Ken; Hayashi, Hideyuki

2007-11-01

To examine the effect of contraction of the anterior capsule opening after cataract surgery on visual acuity and contrast sensitivity. Hayashi Eye Hospital, Fukuoka, Japan. Thirty-two eyes of 32 consecutive patients who showed marked contraction of the anterior capsule opening after implantation of an intraocular lens were recruited. The area of the anterior capsule opening was measured by Scheimpflug videophotography before and after neodymium:YAG (Nd:YAG) laser anterior capsulotomy and was correlated with visual acuity and contrast sensitivity. After Nd:YAG laser anterior capsulotomy, the mean area of the anterior capsule opening increased significantly from 8.2 mm(2) to 18.0 mm(2) (P<.0001). Contrast sensitivity at most visual angles also improved significantly after Nd:YAG anterior capsulotomy, although visual acuity did not. The area of the anterior capsule opening before anterior capsulotomy was correlated significantly with contrast sensitivity but not with visual acuity, whereas there was no correlation between the opening area after anterior capsulotomy and visual acuity or contrast sensitivity. Contraction of the anterior capsule opening after cataract surgery significantly diminished contrast sensitivity in proportion to the opening area but did not markedly worsen visual acuity. Neodymium:YAG laser anterior capsulotomy improved contrast sensitivity.

Demons registration for in vivo and deformable laser scanning confocal endomicroscopy.

PubMed

Chiew, Wei-Ming; Lin, Feng; Seah, Hock Soon

2017-09-01

A critical effect found in noninvasive in vivo endomicroscopic imaging modalities is image distortions due to sporadic movement exhibited by living organisms. In three-dimensional confocal imaging, this effect results in a dataset that is tilted across deeper slices. Apart from that, the sequential flow of the imaging-processing pipeline restricts real-time adjustments due to the unavailability of information obtainable only from subsequent stages. To solve these problems, we propose an approach to render Demons-registered datasets as they are being captured, focusing on the coupling between registration and visualization. To improve the acquisition process, we also propose a real-time visual analytics tool, which complements the imaging pipeline and the Demons registration pipeline with useful visual indicators to provide real-time feedback for immediate adjustments. We highlight the problem of deformation within the visualization pipeline for object-ordered and image-ordered rendering. Visualizations of critical information including registration forces and partial renderings of the captured data are also presented in the analytics system. We demonstrate the advantages of the algorithmic design through experimental results with both synthetically deformed datasets and actual in vivo, time-lapse tissue datasets expressing natural deformations. Remarkably, this algorithm design is for embedded implementation in intelligent biomedical imaging instrumentation with customizable circuitry. (2017) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE).

Demons registration for in vivo and deformable laser scanning confocal endomicroscopy

NASA Astrophysics Data System (ADS)

Chiew, Wei Ming; Lin, Feng; Seah, Hock Soon

2017-09-01

A critical effect found in noninvasive in vivo endomicroscopic imaging modalities is image distortions due to sporadic movement exhibited by living organisms. In three-dimensional confocal imaging, this effect results in a dataset that is tilted across deeper slices. Apart from that, the sequential flow of the imaging-processing pipeline restricts real-time adjustments due to the unavailability of information obtainable only from subsequent stages. To solve these problems, we propose an approach to render Demons-registered datasets as they are being captured, focusing on the coupling between registration and visualization. To improve the acquisition process, we also propose a real-time visual analytics tool, which complements the imaging pipeline and the Demons registration pipeline with useful visual indicators to provide real-time feedback for immediate adjustments. We highlight the problem of deformation within the visualization pipeline for object-ordered and image-ordered rendering. Visualizations of critical information including registration forces and partial renderings of the captured data are also presented in the analytics system. We demonstrate the advantages of the algorithmic design through experimental results with both synthetically deformed datasets and actual in vivo, time-lapse tissue datasets expressing natural deformations. Remarkably, this algorithm design is for embedded implementation in intelligent biomedical imaging instrumentation with customizable circuitry.

Rapid prototyping raw models on the basis of high resolution computed tomography lung data for respiratory flow dynamics.

PubMed

Giesel, Frederik L; Mehndiratta, Amit; von Tengg-Kobligk, Hendrik; Schaeffer, A; Teh, Kevin; Hoffman, E A; Kauczor, Hans-Ulrich; van Beek, E J R; Wild, Jim M

2009-04-01

Three-dimensional image reconstruction by volume rendering and rapid prototyping has made it possible to visualize anatomic structures in three dimensions for interventional planning and academic research. Volumetric chest computed tomography was performed on a healthy volunteer. Computed tomographic images of the larger bronchial branches were segmented by an extended three-dimensional region-growing algorithm, converted into a stereolithography file, and used for computer-aided design on a laser sintering machine. The injection of gases for respiratory flow modeling and measurements using magnetic resonance imaging were done on a hollow cast. Manufacturing the rapid prototype took about 40 minutes and included the airway tree from trackea to segmental bronchi (fifth generation). The branching of the airways are clearly visible in the (3)He images, and the radial imaging has the potential to elucidate the airway dimensions. The results for flow patterns in the human bronchial tree using the rapid-prototype model with hyperpolarized helium-3 magnetic resonance imaging show the value of this model for flow phantom studies.

Characteristics of a Strongly-Pulsed Non-Premixed Jet Flame in Cross-flow

NASA Astrophysics Data System (ADS)

Gamba, Mirko; Clemens, Noel T.; Ezekoye, Ofodike A.

2006-11-01

The effects of large-amplitude, high-frequency harmonic forcing of turbulent nonpremixed hydrogen/methane jet flames in cross-flow (JFICF) are investigated experimentally. Flame lengths, penetration lengths, and mixing characteristics are studied using flame luminosity imaging, planar laser Mie scattering visualization and particle image velocimetry. Mean jet Reynolds numbers of 1,600 and 3,250 (peak Re ˜2,500--6,500) with corresponding mean momentum flux ratios, r, of 1.9 and 3.7 (peak r ˜2.6--8.3) are considered. Forcing frequencies of 100 Hz and 300 Hz with amplitudes of ˜60%--300% are investigated. Consistent with previous work, a drastic decrease in flame length and soot emission, an increase in flame penetration and an improved jet fuel/cross-flow air mixing are observed for the larger forcing amplitude cases. Partial pre-mixing induced by near-field reverse flow, near-field vortex/vortex interaction and large-scale stirring, rendered stronger by large forcing amplitudes and frequencies, are thought to play a key role on the observed effects.

Accidental human laser retinal injuries from military laser systems

NASA Astrophysics Data System (ADS)

Stuck, Bruce E.; Zwick, Harry; Molchany, Jerome W.; Lund, David J.; Gagliano, Donald A.

1996-04-01

The time course of the ophthalmoscopic and functional consequences of eight human laser accident cases from military laser systems is described. All patients reported subjective vision loss with ophthalmoscopic evidence of retinal alteration ranging from vitreous hemorrhage to retinal burn. Five of the cases involved single or multiple exposures to Q-switched neodymium radiation at close range whereas the other three incidents occur over large ranges. Most exposures were within 5 degrees of the foveola, yet none directly in the foveola. High contrast visual activity improved with time except in the cases with progressive retinal fibrosis between lesion sites or retinal hole formation encroaching the fovea. In one patient the visual acuity recovered from 20/60 at one week to 20/25 in four months with minimal central visual field loss. Most cases showed suppression of high and low spatial frequency contrast sensitivity. Visual field measurements were enlarged relative to ophthalmoscopic lesion size observations. Deep retinal scar formation and retinal traction were evident in two of the three cases with vitreous hemorrhage. In one patient, nerve fiber layer damage to the papillo-macular bundle was clearly evident. Visual performance measured with a pursuit tracking task revealed significant performance loss relative to normal tracking observers even in cases where acuity returned to near normal levels. These functional and performance deficits may reflect secondary effects of parafoveal laser injury.

In vivo optical activation of astrocytes as a potential therapeutic strategy for neurodegenerative diseases

NASA Astrophysics Data System (ADS)

Chen, Yuanxin; Mancuso, James; Zhao, Zhen; Li, Xuping; Xue, Zhong; Wong, Stephen T. C.

2013-03-01

Neurovascular dysfunction in many neurodegenerative diseases, such as Alzheimer's disease (AD), reduces blood flow to affected brain areas and causes neuronal dysfunction and loss. A new optical imaging technique is developed to activate astrocytes in live animal models in order to investigate the increase of local cerebral blood flow as a potential therapeutic strategy for AD. The technique uses fluorescent labeling of vasculature and astrocytes coupled with intravital 2-photon microscopy to visualize the astrocyte-vasculature interactions in live animals. Using femtosecond laser stimulation, calcium uncaging is applied to specifically target and activate astrocytes in vivo with high spatial and temporal resolutions. Intravital 2-photon microscopy imaging was employed to demonstrate that single endfoot optical activation around an arteriole induced a 25% increase in arteriole diameter, which in turn increased cerebral local blood flow in down-stream capillaries. This quantitative result indicates the potential of using optical activation of astrocytes in afflicted brain areas of neurodegeneration to restore normal neurovascular functions.

Generation of microfluidic flow using an optically assembled and magnetically driven microrotor

NASA Astrophysics Data System (ADS)

Köhler, J.; Ghadiri, R.; Ksouri, S. I.; Guo, Q.; Gurevich, E. L.; Ostendorf, A.

2014-12-01

The key components in microfluidic systems are micropumps, valves and mixers. Depending on the chosen technology, the realization of these microsystems often requires rotational and translational control of subcomponents. The manufacturing of such active components as well as the driving principle are still challenging tasks. A promising all-optical approach could be the combination of laser direct writing and actuation based on optical forces. However, when higher actuation velocities are required, optical driving might be too slow. Hence, a novel approach based on optical assembling of microfluidic structures and subsequent magnetic actuation is proposed. By applying the optical assembly of microspherical building blocks as the manufacturing method and magnetic actuation, a microrotor was successfully fabricated and tested within a microfluidic channel. The resulting fluid flow was characterized by introducing an optically levitated measuring probe particle. Finally, a freely moving tracer particle visualizes the generated flow. The tracer particle analysis shows average velocities of 0.4-0.5 µm s-1 achieved with the presented technology.

The NASA Langley Isolator Dynamics Research Lab

NASA Technical Reports Server (NTRS)

Middleton, Troy F.; Balla, Robert J.; Baurle, Robert A.; Humphreys, William M.; Wilson, Lloyd G.

2010-01-01

The Isolator Dynamics Research Lab (IDRL) is under construction at the NASA Langley Research Center in Hampton, Virginia. A unique test apparatus is being fabricated to support both wall and in-stream measurements for investigating the internal flow of a dual-mode scramjet isolator model. The test section is 24 inches long with a 1-inch by 2-inch cross sectional area and is supplied with unheated, dry air through a Mach 2.5 converging-diverging nozzle. The test section is being fabricated with two sets (glass and metallic) of interchangeable sidewalls to support flow visualization and laser-based measurement techniques as well as static pressure, wall temperature, and high frequency pressure measurements. During 2010, a CFD code validation experiment will be conducted in the lab in support of NASA s Fundamental Aerodynamics Program. This paper describes the mechanical design of the Isolator Dynamics Research Lab test apparatus and presents a summary of the measurement techniques planned for investigating the internal flow field of a scramjet isolator model.

Visualization of in vivo metabolic flows reveals accelerated utilization of glucose and lactate in penumbra of ischemic heart

PubMed Central

Sugiura, Yuki; Katsumata, Yoshinori; Sano, Motoaki; Honda, Kurara; Kajimura, Mayumi; Fukuda, Keiichi; Suematsu, Makoto

2016-01-01

Acute ischemia produces dynamic changes in labile metabolites. To capture snapshots of such acute metabolic changes, we utilized focused microwave treatment to fix metabolic flow in vivo in hearts of mice 10 min after ligation of the left anterior descending artery. The left ventricle was subdivided into short-axis serial slices and the metabolites were analyzed by capillary electrophoresis mass spectrometry and matrix-assisted laser desorption/ionization imaging mass spectrometry. These techniques allowed us to determine the fate of exogenously administered 13C6-glucose and 13C3-lactate. The penumbra regions, which are adjacent to the ischemic core, exhibited the greatest adenine nucleotide energy charge and an adenosine overflow extending from the ischemic core, which can cause ischemic hyperemia. Imaging analysis of metabolic pathway flows revealed that the penumbra executes accelerated glucose oxidation, with remaining lactate utilization for tricarboxylic acid cycle for energy compensation, suggesting unexpected metabolic interplays of the penumbra with the ischemic core and normoxic regions. PMID:27581923

Radiation beam calorimetric power measurement system

DOEpatents

Baker, John; Collins, Leland F.; Kuklo, Thomas C.; Micali, James V.

1992-01-01

A radiation beam calorimetric power measurement system for measuring the average power of a beam such as a laser beam, including a calorimeter configured to operate over a wide range of coolant flow rates and being cooled by continuously flowing coolant for absorbing light from a laser beam to convert the laser beam energy into heat. The system further includes a flow meter for measuring the coolant flow in the calorimeter and a pair of thermistors for measuring the temperature difference between the coolant inputs and outputs to the calorimeter. The system also includes a microprocessor for processing the measured coolant flow rate and the measured temperature difference to determine the average power of the laser beam.

Laser Doppler anemometer signal processing for blood flow velocity measurements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Borozdova, M A; Fedosov, I V; Tuchin, V V

A new method for analysing the signal in a laser Doppler anemometer based on the differential scheme is proposed, which provides the flow velocity measurement in strongly scattering liquids, particularly, blood. A laser Doppler anemometer intended for measuring the absolute blood flow velocity in animal and human near-surface arterioles and venules is developed. The laser Doppler anemometer signal structure is experimentally studied for measuring the flow velocity in optically inhomogeneous media, such as blood and suspensions of scattering particles. The results of measuring the whole and diluted blood flow velocity in channels with a rectangular cross section are presented. (lasermore » applications and other topics in quantum electronics)« less

Thomson scattering measurements from asymmetric interpenetrating plasma flows

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ross, J. S., E-mail: ross36@llnl.gov; Moody, J. D.; Fiuza, F.

2014-11-15

Imaging Thomson scattering measurements of collective ion-acoustic fluctuations have been utilized to determine ion temperature and density from laser produced counter-streaming asymmetric flows. Two foils are heated with 8 laser beams each, 500 J per beam, at the Omega Laser facility. Measurements are made 4 mm from the foil surface using a 60 J 2ω probe laser with a 200 ps pulse length. Measuring the electron density and temperature from the electron-plasma fluctuations constrains the fit of the multi-ion species, asymmetric flows theoretical form factor for the ion feature such that the ion temperatures, ion densities, and flow velocities formore » each plasma flow are determined.« less

Tip-leakage cavitation in the clearance of a 2D hydrofoil with fillets: high-speed visualization and PIV/PTV measurements

NASA Astrophysics Data System (ADS)

Zapryagaev, Ivan I.; Timoshevskiy, Mikhail V.; Pervunin, Konstantin S.

2017-09-01

Tip-clearance cavitation is one of the most aggressive forms of cavitation as it can cause surface erosion of hydraulic machinery elements and, as a result, their fatigue damage and disturb designed operating conditions. At present, the literature lacks for detailed experimental data on the inception and development of this type of cavitation at various flow conditions. In the paper, a tip-leakage cavitation occurring in the clearance between an end face of a 2D hydrofoil (a scaled-down model of guide vanes (GV) of a Francis turbine) and a transparent wall of the test section was studied. The experiments were carried out for different cavitating regimes on the cavitation number and two attack angles of 3° and 9°, with the gap size (tip clearance width) varied in the range from 0.4 to 0.8 mm. In order to determine the cavitation inception conditions and investigate the dynamics of the tip-leakage cavitation, a high-speed visualization was applied. A modified PIV/PTV technique with a diverging laser beam instead of a laser light sheet was used to measure the mean velocity distributions within the gap. It was shown that the cavitation pattern on the suction side of the GV model impacts the dynamics of the leakage flow in the gap but does not affect the sheet cavity formed close to the foil leading edge in the clearance as well as its size and dynamics. When the gap size is increased, the tip-leakage cavitation initiates at higher cavitation numbers or, in other words, conditions for the cavitation occurrence become more favorable.

Pipe flow measurements of turbulence and ambiguity using laser-Doppler velocimetry

NASA Technical Reports Server (NTRS)

Berman, N. S.; Dunning, J. W.

1973-01-01

The laser-Doppler ambiguities predicted by George and Lumley (1973) have been verified experimentally for turbulent pipe flows. Experiments were performed at Reynolds numbers from 5000 to 15,000 at the center line and near the wall. Ambiguity levels were measured from power spectral densities of FM demodulated laser signals and were compared with calculations based on the theory. The turbulent spectra for these water flows after accounting for the ambiguity were equivalent to hot-film measurements at similar Reynolds numbers. The feasibility of laser-Doppler measurements very close to the wall in shear flows is demonstrated.

Flow characteristics and spillage mechanisms of wall-mounted and jet-isolated range hoods subject to influence from cross draft.

PubMed

Chen, Jia-Kun; Huang, Rong Fung; Peng, Kuan-Lin

2012-01-01

The effects of draft on the flow and spillage characteristics of wall-mounted and jet-isolated range hoods were investigated. A specially designed draft generator that could supply low-swirl air current was used to provide "cross draft" from three directions, lateral (θ = 0(o)), oblique (θ = 45(o)), and front (θ = 90(o)), with respect to the center point of the range hoods. Flow characteristics of oil mist were inspected through visualization of smoke flows with light scattering (laser light sheet-assisted visualization of smoke flow). The leakage mechanisms, which were closely related to the flow features, were studied by examining both movies and still pictures showing smoke-flow evolution. The sulfur hexafluoride tracer gas concentration detection method was employed to measure the capture indices. The results showed that the lateral draft pushed the pollutants generated under the hood in the opposite direction and induced serious spillage. The oblique draft pushed the pollutants toward both the rear wall and opposite side and induced more serious spillage than did the lateral draft. The frontal draft forced the pollutants to bifurcate into streams moving toward the left and the right, and induced the most serious pollutant spillage among the three tested drafts. Pollutant spillage became critically significant as the cross draft velocity was increased to greater than 0.2 m/sec. Spillage of pollutants increased as the velocity of the cross draft was increased. Increasing the suction flow rate of the range hood may increase resistance to the draft, but the benefits were limited at draft velocities greater than 0.2 m/sec. Both range hoods had a similarly low capture index under the influence of the lateral draft. For the oblique and frontal drafts, the jet-isolated range hood demonstrated a higher capture index than did the wall-mounted range hood.

Visual servoing of a laser ablation based cochleostomy

NASA Astrophysics Data System (ADS)

Kahrs, Lüder A.; Raczkowsky, Jörg; Werner, Martin; Knapp, Felix B.; Mehrwald, Markus; Hering, Peter; Schipper, Jörg; Klenzner, Thomas; Wörn, Heinz

2008-03-01

The aim of this study is a defined, visually based and camera controlled bone removal by a navigated CO II laser on the promontory of the inner ear. A precise and minimally traumatic opening procedure of the cochlea for the implantation of a cochlear implant electrode (so-called cochleostomy) is intended. Harming the membrane linings of the inner ear can result in damage of remaining organ functions (e.g. complete deafness or vertigo). A precise tissue removal by a laser-based bone ablation system is investigated. Inside the borehole the pulsed laser beam is guided automatically over the bone by using a two mirror galvanometric scanner. The ablation process is controlled by visual servoing. For the detection of the boundary layers of the inner ear the ablation area is monitored by a color camera. The acquired pictures are analyzed by image processing. The results of this analysis are used to control the process of laser ablation. This publication describes the complete system including image processing algorithms and the concept for the resulting distribution of single laser pulses. The system has been tested on human cochleae in ex-vivo studies. Further developments could lead to safe intraoperative openings of the cochlea by a robot based surgical laser instrument.

Influence Of Low Intensity Laser Therapy On Diabetic Polyneuropathy

NASA Astrophysics Data System (ADS)

Abdel-Raoof, N. A.; Elnhas, N. G.; Elsayed, I. M.

2011-09-01

Diabetic peripheral neuropathy is a consequence of diabetes-mediated impairment of blood flow, and resultant hypoxia of nerves that may develop within 10 years of the onset of diabetes in 40-50% of people with type 1 or type 2 diabetes. Low Intensity Laser Therapy (LILT) has been advocated for the treatment of chronic pain disorders as blood flow is an important determinant for pain relief. Comparing the effect of Helium-Neon Laser therapy versus Infrared laser therapy on blood vessels diameter and flow as well as level of sensation for neuropathy. Twenty diabetic patients suffering from neuropathy were enrolled in the study with age 45-55 years. They were assigned randomly into two equal groups in number; Group A underwent an application of He-Neon laser while Group B underwent an application of Infrared laser. Both groups received laser for 2 months. Blood flow velocity, and blood vessel diameter were investigated by using duplex Doppler ultrasound and peripheral neuropathy parameters were investigated by Semmes-Weinstein monofilament assessment. The results revealed that He-Neon laser as well as Infrared laser groups showed significant improvement in blood flow velocity, blood vessel diameter & neuropathy tested parameters after treatment but there was no significance difference between the two types of LILT. LILT is a safe, non-invasive and drug free method for improving blood flow & sensation in patients suffering from diabetic polyneuropathy in addition to preventing one of the most threatening microvascular complications of diabetes.

Endoscopic laser-urethroplasty

NASA Astrophysics Data System (ADS)

Gilbert, Peter

2006-02-01

The objective was to prove the advantage of endoscopic laser-urethroplasty over internal urethrotomy in acquired urethral strictures. Patients and Method: From January, 1996 to June, 2005, 35 patients with a mean age of 66 years were submitted to endoscopic laser-urethroplasty for strictures of either the bulbar (30) or membranous (5) urethra. The operations were carried out under general anesthesia. First of all, the strictures were incised at the 4, 8 and 12 o'clock position by means of a Sachse-urethrotom. Then the scar flap between the 4 and 8 o'clock position was vaporized using a Nd:YAG laser, wavelength 1060 nm and a 600 pm bare fiber, the latter always being in contact with the tissue. The laser worked at 40W power in continuous mode. The total energy averaged 2574 J. An indwelling catheter was kept in place overnight and the patients were discharged the following day. Urinalysis, uroflowmetry and clinical examination were performed at two months after surgery and from then on every six months. Results: No serious complications were encountered. Considering a mean follow-up of 18 months, the average peak flow improved from 7.3 ml/s preoperatively to 18.7 mVs postoperatively. The treatment faded in 5 patients ( 14.3% ) who finally underwent open urethroplasty. Conclusions: Endoscopic laser-urethroplasty yields better short-term results than internal visual urethrotomy. Long-term follow-up has yet to confirm its superiority in the treatment of acquired urethral strictures.

Investigation of a reacting jet injected into vitiated crossflow using CARS, high repetition rate OH-PLIF, and high repetition rate PIV

NASA Astrophysics Data System (ADS)

Roa, Mario

The proposed PhD thesis research program will be carried out in a staged combustion test rig developed with funding from Siemens Power Generation Inc. and the United States Department of Energy. This research program will study the reacting flow field created by an injector that is axially distributed along the combustor with use the laser diagnostics methods: Coherent Anti-Stokes Raman Spectroscopy (CARS), high repetition rate OH Planar Laser Induced Florescence (OHPLIF), and high repetition rate Particle Image Velocimetry (PIV), to determine why certain conditions result in low NOx emissions. This data will be used to validated the development of more precise computer models. These laser diagnostic techniques will be applied to the reacting jet produced using an extended, premixed 10 mm injector using both natural gas (NG) and hydrogen (H2) as fuels. The objective of this thesis research is to use advance laser diagnostics to gain insight into the reacting flow field resulting form transverse injection into a vitiated cross flow. The advance laser diagnostics will also provide insight into pollution formation mechanisms and will be used for validating CFD models of the transverse jet injection. The following measurements will be performed: (1) dual pump nitrogen/hydrogen (H2/ N2) CARS at the midplane of the extended 10 mm nozzle, (2) high repetition rate OH-PLIF and emission sampling for the same extended nozzle using NG and H2 as secondary fuel, (3) and combing both high repetition OH-PLIF and high repetition rate PIV for extended 10 mm nozzle for both NG and H2 secondary fuel. The PIV measurements will be combined with OH-PLIF in a simultaneous manner, with the OH fluorescence centered between the two PIV laser pulses. The dual pump H2/N2 CARS system will be used to measure both temperature of the reacting jet and the species concentration ratio of H2/ N2. The high repetition rate OH-PLIF, conducted with a 5 kHz, dual cavity Nd:YAG laser that optically pumps a dye laser tuned to the Q1(7) OH florescence transition. It will be used to visualize the flame front of the reacting jet. The high repetition rate PIV will be performed with a dual cavity laser at 10 kHz. High repetition rate PIV will be used to characterize the velocity and vortical structures produced in the reacting flow field. This research project will aid in the understanding of NOx creation in an staged gas turbine combustor and provide crucial data that will be used to develop precise computer models that will be used in designing the next power generation gas turbines. As power generation turbines increase in usage in future due to the abundance of NG as a fuel source or H 2 gas produced via green energy policies, it will be vital to make these new generation turbines more efficient and further reduce pollutant emission levels.

The characterisation and application of a pulsed neodymium YAG laser DGV system to a time-varying high-speed flow

NASA Astrophysics Data System (ADS)

Thorpe, S. J.; Quinlan, N.; Ainsworth, R. W.

2000-10-01

Doppler Global Velocimetry (DGV) is a whole-field measurement technique which has attracted significant interest from the fluid-flow research community since its introduction in 1991. Practical implementations of the methodology have focused on two principal laser light sources: the argon ion laser, applied to steady state or slowly varying flows; and the pulsed neodymium YAG laser for the measurement of instantaneous velocity fields. However, the emphasis in the published literature has been very much on research using the argon laser. This paper reports the application of a Q-switched, injection-seeded neodymium YAG laser to the proven Oxford DGV system, and the use of this combination in a short duration unsteady high-speed flow. The pertinent characteristics of the apparatus are described, and the impact of these on the integrity of the resulting velocity measurements is presented. Adaptations to the commercial laser system that make it suitable for application to the measurement of transient high-speed flows are described. Finally, the application of this system to a short duration unsteady flow is described. This application is based on the flow found in a new type of transdermal drug delivery device, where particles of the drug material are projected at high speed through the skin. Whole-field velocities are recorded, and values as high as 800 m/ s are evident.

Database structure for the Laser Accident and Incident Registry (LAIR)

NASA Astrophysics Data System (ADS)

Ness, James W.; Hoxie, Stephen W.; Zwick, Harry; Stuck, Bruce E.; Lund, David J.; Schmeisser, Elmar T.

1997-05-01

The ubiquity of laser radiation in military, medical, entertainment, telecommunications and research industries and the significant risk, of eye injury from this radiation are firmly established. While important advances have been made in understanding laser bioeffects using animal analogues and clinical data, the relationships among patient characteristics, exposure conditions, severity of the resulting injury, and visual function are fragmented, complex and varied. Although accident cases are minimized through laser safety regulations and control procedures, accumulated accident case information by the laser eye injury evaluation center warranted the development of a laser accident and incident registry. The registry includes clinical data for validating and refining hypotheses on injury and recovery mechanisms; a means for analyzing mechanisms unique to human injury; and a means for identifying future areas of investigation. The relational database supports three major sections: (1) the physics section defines exposure circumstances, (2) the clinical/ophthalmologic section includes fundus and scanning laser ophthalmoscope images, and (3) the visual functions section contains specialized visual function exam results. Tools are available for subject-matter experts to estimate parameters like total intraocular energy, ophthalmic lesion grade, and exposure probability. The database is research oriented to provide a means for generating empirical relationships to identify symptoms for definitive diagnosis and treatment of laser induced eye injuries.

Laser light visual cueing for freezing of gait in Parkinson disease: A pilot study with male participants.

PubMed

Bunting-Perry, Lisette; Spindler, Meredith; Robinson, Keith M; Noorigian, Joseph; Cianci, Heather J; Duda, John E

2013-01-01

Freezing of gait (FOG) is a debilitating feature of Parkinson disease (PD). In this pilot study, we sought to assess the efficacy of a rolling walker with a laser beam visual cue to treat FOG in PD patients. We recruited 22 subjects with idiopathic PD who experienced on- and off-medication FOG. Subjects performed three walking tasks both with and without the laser beam while on medications. Outcome measures included time to complete tasks, number of steps, and number of FOG episodes. A crossover design allowed within-group comparisons between the two conditions. No significant differences were observed between the two walking conditions across the three tasks. The laser beam, when applied as a visual cue on a rolling walker, did not diminish FOG in this study.

A unified planar measurement technique for compressible flows using laser-induced iodine fluorescence

NASA Technical Reports Server (NTRS)

Hartfield, Roy J., Jr.; Hollo, Steven D.; Mcdaniel, James C.

1992-01-01

A unified laser-induced fluorescence technique for conducting planar measurements of temperature, pressure and velocity in nonreacting, highly compressible flows has been developed, validated and demonstrated. Planar fluorescence from iodine, seeded into air, was induced by an argon-ion laser and collected using a liquid-nitrogen cooled CCD camera. In the measurement technique, temperature is determined from the fluorescence induced with the laser operated broad band. Pressure and velocity are determined from the shape and position of the fluorescence excitation spectrum which is measured with the laser operated narrow band. The measurement approach described herein provides a means of obtaining accurate, spatially-complete maps of the primary flow field parameters in a wide variety of cold supersonic and transonic flows.

Application of laser Doppler velocimeter to chemical vapor laser system

NASA Technical Reports Server (NTRS)

Gartrell, Luther R.; Hunter, William W., Jr.; Lee, Ja H.; Fletcher, Mark T.; Tabibi, Bagher M.

1993-01-01

A laser Doppler velocimeter (LDV) system was used to measure iodide vapor flow fields inside two different-sized tubes. Typical velocity profiles across the laser tubes were obtained with an estimated +/-1 percent bias and +/-0.3 to 0.5 percent random uncertainty in the mean values and +/-2.5 percent random uncertainty in the turbulence-intensity values. Centerline velocities and turbulence intensities for various longitudinal locations ranged from 13 to 17.5 m/sec and 6 to 20 percent, respectively. In view of these findings, the effects of turbulence should be considered for flow field modeling. The LDV system provided calibration data for pressure and mass flow systems used routinely to monitor the research laser gas flow velocity.

Can transmyocardial CO2 laser channels supply nutritive blood flow into adjacent myocardium?

NASA Astrophysics Data System (ADS)

Kohmoto, Takushi; Fisher, Peter E.; DeRosa, Carolyn; Smith, Craig R.; Burkhoff, Daniel

1996-05-01

Clinical reports of transmyocardial laser revascularization (TMLR) suggest that this procedure is effective in relieving angina. However, experimental evidence of nutritive blood flow through the TMLR channels is not available. The purpose of this study was to test whether blood could flow through the TMLR channels created with the carbon-dioxide laser.

VisFlow - Web-based Visualization Framework for Tabular Data with a Subset Flow Model.

PubMed

Yu, Bowen; Silva, Claudio T

2017-01-01

Data flow systems allow the user to design a flow diagram that specifies the relations between system components which process, filter or visually present the data. Visualization systems may benefit from user-defined data flows as an analysis typically consists of rendering multiple plots on demand and performing different types of interactive queries across coordinated views. In this paper, we propose VisFlow, a web-based visualization framework for tabular data that employs a specific type of data flow model called the subset flow model. VisFlow focuses on interactive queries within the data flow, overcoming the limitation of interactivity from past computational data flow systems. In particular, VisFlow applies embedded visualizations and supports interactive selections, brushing and linking within a visualization-oriented data flow. The model requires all data transmitted by the flow to be a data item subset (i.e. groups of table rows) of some original input table, so that rendering properties can be assigned to the subset unambiguously for tracking and comparison. VisFlow features the analysis flexibility of a flow diagram, and at the same time reduces the diagram complexity and improves usability. We demonstrate the capability of VisFlow on two case studies with domain experts on real-world datasets showing that VisFlow is capable of accomplishing a considerable set of visualization and analysis tasks. The VisFlow system is available as open source on GitHub.

Topographic steep central islands following excimer laser photorefractive keratectomy

NASA Astrophysics Data System (ADS)

Krueger, Ronald R.; McDonnell, Peter J.

1994-06-01

The purpose of this study is to demonstrate that topographic irregularities in the form of central islands of higher refractive power can be seen following excimer laser refractive surgery. We reviewed the computerized corneal topographic maps of 35 patients undergoing excimer laser PRK for compound myopic astigmatism or anisometropia from 8/91 to 8/93 at the USC/Doheny Eye Institute. The topographic maps were generated by the Computed Anatomy Corneal Modeling System, and central islands were defined as topographic areas of steepening of at least 3 diopters and 3 mm in diameter. A grading system was developed based on the presence of central islands during the postoperative period. Visually significant topographic steep central islands may be seen in over 50% of patients at 1 month following excimer laser PRK, and persist at 3 months in up to 24% of patients without nitrogen gas blowing. Loss of best corrected visual acuity or ghosting is associated with island formation, and may prolong visual rehabilitation after excimer laser PRK.

System for controlling the flow of gas into and out of a gas laser

DOEpatents

Alger, Terry; Uhlich, Dennis M.; Benett, William J.; Ault, Earl R.

1994-01-01

A modularized system for controlling the gas pressure within a copper vapor or like laser is described herein. This system includes a gas input assembly which serves to direct gas into the laser in a controlled manner in response to the pressure therein for maintaining the laser pressure at a particular value, for example 40 torr. The system also includes a gas output assembly including a vacuum pump and a capillary tube arrangement which operates within both a viscous flow region and a molecular flow region for drawing gas out of the laser in a controlled manner.

Blood oxygenation and flow measurements using a single 720-nm tunable V-cavity laser.

PubMed

Feng, Yafei; Deng, Haoyu; Chen, Xin; He, Jian-Jun

2017-08-01

We propose and demonstrate a single-laser-based sensing method for measuring both blood oxygenation and microvascular blood flow. Based on the optimal wavelength range found from theoretical analysis on differential absorption based blood oxygenation measurement, we designed and fabricated a 720-nm-band wavelength tunable V-cavity laser. Without any grating or bandgap engineering, the laser has a wavelength tuning range of 14.1 nm. By using the laser emitting at 710.3 nm and 724.4 nm to measure the oxygenation and blood flow, we experimentally demonstrate the proposed method.

Comparison of KTP, Thulium, and CO2 laser in stapedotomy using specialized visualization techniques: thermal effects.

PubMed

Kamalski, Digna M A; Verdaasdonk, Rudolf M; de Boorder, Tjeerd; Vincent, Robert; Trabelzini, Franco; Grolman, Wilko

2014-06-01

High-speed thermal imaging enables visualization of heating of the vestibule during laser-assisted stapedotomy, comparing KTP, CO2, and Thulium laser light. Perforation of the stapes footplate with laser bears the risk of heating of the inner ear fluids. The amount of heating depends on absorption of the laser light and subsequent tissue ablation. The ablation of the footplate is driven by strong water absorption for the CO2 and Thulium laser. For the KTP laser wavelength, ablation is driven by carbonization of the footplate and it might penetrate deep into the inner ear without absorption in water. The thermal effects were visualized in an inner ear model, using two new techniques: (1) high-speed Schlieren imaging shows relative dynamic changes of temperatures up to 2 ms resolution in the perilymph. (2) Thermo imaging provides absolute temperature measurements around the footplate up to 40 ms resolution. The high-speed Schlieren imaging showed minimal heating using the KTP laser. Both CO2 and Thulium laser showed heating below the footplate. Thulium laser wavelength generated heating up to 0.6 mm depth. This was confirmed with thermal imaging, showing a rise of temperature of 4.7 (±3.5) °C for KTP and 9.4 (±6.9) for Thulium in the area of 2 mm below the footplate. For stapedotomy, the Thulium and CO2 laser show more extended thermal effects compared to KTP. High-speed Schlieren imaging and thermal imaging are complimentary techniques to study lasers thermal effects in tissue.

Longitudinal In Vivo Imaging to Assess Blood Flow and Oxygenation in Implantable Engineered Tissues

PubMed Central

White, Sean M.; Hingorani, Ryan; Arora, Rajan P.S.; Hughes, Christopher C.W.; George, Steven C.

2012-01-01

The functionality of vascular networks within implanted prevascularized tissues is difficult to assess using traditional analysis techniques, such as histology. This is largely due to the inability to visualize hemodynamics in vivo longitudinally. Therefore, we have developed dynamic imaging methods to measure blood flow and hemoglobin oxygen saturation in implanted prevascularized tissues noninvasively and longitudinally. Using laser speckle imaging, multispectral imaging, and intravital microscopy, we demonstrate that fibrin-based tissue implants anastomose with the host (severe combined immunodeficient mice) in as short as 20 h. Anastomosis results in initial perfusion with highly oxygenated blood, and an increase in average hemoglobin oxygenation of 53%. However, shear rates in the preformed vessels were low (20.8±12.8 s−1), and flow did not persist in the vast majority of preformed vessels due to thrombus formation. These findings suggest that designing an appropriate vascular network structure in prevascularized tissues to maintain shear rates above the threshold for thrombosis may be necessary to maintain flow following implantation. We conclude that wide-field and microscopic functional imaging can dynamically assess blood flow and oxygenation in vivo in prevascularized tissues, and can be used to rapidly evaluate and improve prevascularization strategies. PMID:22435776

Investigation of three-dimensional flow field in a turbine including rotor/stator interaction. I - Design development and performance of the research facility

NASA Technical Reports Server (NTRS)

Lakshminarayana, B.; Camci, C.; Halliwell, I.; Zaccaria, M.

1992-01-01

A description of the Axial Flow Turbine Research Facility (AFTRF) installed at the Turbomachinery Laboratory of the Pennsylvania State University is presented in this paper. The facility diameter is 91.66 cm (3 feet) and the hub-to-tip ratio of the blading is 0.73. The flow path consists of turbulence generating grid, 23 nozzle vane and 29 rotor blades followed by outlet guide vanes. The blading design, carried out by General Electric Company personnel, embody modern HP turbine design philosophy, loading and flow coefficient, reaction, aspect ratio, and blade turning angles; all within the current aircraft engine design turbine practice. State-of-the-art quasi-3D blade design techniques were used to design the vane and the blade shapes. The vanes and blades are heavily instrumented with fast response pressure, shear stress, and velocity probes and have provision for flow visualization and laser Doppler anemometer measurement. Furthermore, provision has been made for detailed nozzle wake, rotor wake and boundary layer surveys. A 150 channel slip ring unit is used for transmitting the rotor data to a stationary instrumentation system. All the design objectives have been met.

Quality Assurance By Laser Scanning And Imaging Techniques

NASA Astrophysics Data System (ADS)

SchmalfuB, Harald J.; Schinner, Karl Ludwig

1989-03-01

Laser scanning systems are well established in the world of fast industrial in-process quality inspection systems. The materials inspected by laser scanning systems are e.g. "endless" sheets of steel, paper, textile, film or foils. The web width varies from 50 mm up to 5000 mm or more. The web speed depends strongly on the production process and can reach several hundred meters per minute. The continuous data flow in one of different channels of the optical receiving system exceeds ten Megapixels/sec. Therefore it is clear that the electronic evaluation system has to process these data streams in real time and no image storage is possible. But sometimes (e.g. first installation of the system, change of the defect classification) it would be very helpful to have the possibility for a visual look on the original, i.e. not processed sensor data. At first we show the principle set up of a standard laser scanning system. Then we will introduce a large image memory especially designed for the needs of high-speed inspection sensors. This image memory co-operates with the standard on-line evaluation electronics and provides therefore an easy comparison between processed and non-processed data. We will discuss the basic system structure and we will show the first industrial results.

Optical discharge with absorption of repetitive CO{sub 2} laser pulses in supersonic air flow: wave structure and condition of a quasi-steady state

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bobarykina, T A; Malov, A N; Orishich, A M

We report a study of the wave structure formed by an optical discharge plasma upon the absorption of repetitively pulsed CO{sub 2} laser radiation in a supersonic (M = 1.36) air flow. Experimental data are presented on the configuration of the head shock wave and the geometry and characteristic dimensions of breakdown regions behind a laser plasma pulsating in the flow at a frequency of up to 150 kHz. The data are compared to calculation in a point explosion model with allowance for counterpressure, which makes it possible to identify the relationship between laser radiation and supersonic flow parameters thatmore » ensures quasisteady- state energy delivery and is necessary for extending the possibilities of controlling the structure of supersonic flows. (interaction of laser radiation with matter)« less

Wide-area mapping of resting state hemodynamic correlations at microvascular resolution with multi-contrast optical imaging (Conference Presentation)

NASA Astrophysics Data System (ADS)

Senarathna, Janaka; Hadjiabadi, Darian; Gil, Stacy; Thakor, Nitish V.; Pathak, Arvind P.

2017-02-01

Different brain regions exhibit complex information processing even at rest. Therefore, assessing temporal correlations between regions permits task-free visualization of their `resting state connectivity'. Although functional MRI (fMRI) is widely used for mapping resting state connectivity in the human brain, it is not well suited for `microvascular scale' imaging in rodents because of its limited spatial resolution. Moreover, co-registered cerebral blood flow (CBF) and total hemoglobin (HbT) data are often unavailable in conventional fMRI experiments. Therefore, we built a customized system that combines laser speckle contrast imaging (LSCI), intrinsic optical signal (IOS) imaging and fluorescence imaging (FI) to generate multi-contrast functional connectivity maps at a spatial resolution of 10 μm. This system comprised of three illumination sources: a 632 nm HeNe laser (for LSCI), a 570 nm ± 5 nm filtered white light source (for IOS), and a 473 nm blue laser (for FI), as well as a sensitive CCD camera operating at 10 frames per second for image acquisition. The acquired data enabled visualization of changes in resting state neurophysiology at microvascular spatial scales. Moreover, concurrent mapping of CBF and HbT-based temporal correlations enabled in vivo mapping of how resting brain regions were linked in terms of their hemodynamics. Additionally, we complemented this approach by exploiting the transit times of a fluorescent tracer (Dextran-FITC) to distinguish arterial from venous perfusion. Overall, we demonstrated the feasibility of wide area mapping of resting state connectivity at microvascular resolution and created a new toolbox for interrogating neurovascular function.

Aero-optics overview. [laser applications

NASA Technical Reports Server (NTRS)

Gilbert, K. G.

1980-01-01

Various aero-optical phenomena are discussed with reference to their effect on airborne high energy lasers. Major emphasis is placed on: compressibility effects induced in the surrounding flow field; viscous effects which manifests themselves as aircraft boundary layers or shear layers; inviscid flow fields surrounding the aircraft due to airflow around protuberance such as laser turret assemblies; and shocks, established whenever local flow exceeds Mach one. The significant physical parameters affecting the interaction of a laser beam with a turbulent boundary layer are also described.

Planar temperature measurement in compressible flows using laser-induced iodine fluorescence

NASA Technical Reports Server (NTRS)

Hartfield, Roy J., Jr.; Hollo, Steven D.; Mcdaniel, James C.

1991-01-01

A laser-induced iodine fluorescence technique that is suitable for the planar measurement of temperature in cold nonreacting compressible air flows is investigated analytically and demonstrated in a known flow field. The technique is based on the temperature dependence of the broadband fluorescence from iodine excited by the 514-nm line of an argon-ion laser. Temperatures ranging from 165 to 245 K were measured in the calibration flow field. This technique makes complete, spatially resolved surveys of temperature practical in highly three-dimensional, low-temperature compressible flows.

The gelatinous extracellular matrix facilitates transport studies in kelp: visualization of pressure-induced flow reversal across sieve plates

PubMed Central

Knoblauch, Jan; Peters, Winfried S.; Knoblauch, Michael

2016-01-01

Background and Aims In vascular plants, important questions regarding phloem function remain unanswered due to problems with invasive experimental procedures in this highly sensitive tissue. Certain brown algae (kelps; Laminariales) also possess sieve tubes for photoassimilate transport, but these are embedded in large volumes of a gelatinous extracellular matrix which isolates them from neighbouring cells. Therefore, we hypothesized that kelp sieve tubes might tolerate invasive experimentation better than their analogues in higher plants, and sought to establish Nereocystis luetkeana as an experimental system. Methods The predominant localization of cellulose and the gelatinous extracellular matrix in N. luetkeana was verified using specific fluorescent markers and confocal laser scanning microscopy. Sieve tubes in intact specimens were loaded with fluorescent dyes, either passively (carboxyfluorescein diacetate; CFDA) or by microinjection (rhodamine B), and the movement of the dyes was monitored by fluorescence microscopy. Key Results Application of CFDA demonstrated source to sink bulk flow in N. luetkeana sieve tubes, and revealed the complexity of sieve tube structure, with branches, junctions and lateral connections. Microinjection into sieve elements proved comparatively easy. Pulsed rhodamine B injection enabled the determination of flow velocity in individual sieve elements, and the direct visualization of pressure-induced reversals of flow direction across sieve plates. Conclusions The reversal of flow direction across sieve plates by pressurizing the downstream sieve element conclusively demonstrates that a critical requirement of the Münch theory is satisfied in kelp; no such evidence exists for tracheophytes. Because of the high tolerance of its sieve elements to experimental manipulation, N. luetkeana is a promising alternative to vascular plants for studying the fluid mechanics of sieve tube networks. PMID:26929203

The gelatinous extracellular matrix facilitates transport studies in kelp: visualization of pressure-induced flow reversal across sieve plates.

PubMed

Knoblauch, Jan; Peters, Winfried S; Knoblauch, Michael

2016-04-01

In vascular plants, important questions regarding phloem function remain unanswered due to problems with invasive experimental procedures in this highly sensitive tissue. Certain brown algae (kelps; Laminariales) also possess sieve tubes for photoassimilate transport, but these are embedded in large volumes of a gelatinous extracellular matrix which isolates them from neighbouring cells. Therefore, we hypothesized that kelp sieve tubes might tolerate invasive experimentation better than their analogues in higher plants, and sought to establish Nereocystis luetkeana as an experimental system. The predominant localization of cellulose and the gelatinous extracellular matrix in N. luetkeana was verified using specific fluorescent markers and confocal laser scanning microscopy. Sieve tubes in intact specimens were loaded with fluorescent dyes, either passively (carboxyfluorescein diacetate; CFDA) or by microinjection (rhodamine B), and the movement of the dyes was monitored by fluorescence microscopy. Application of CFDA demonstrated source to sink bulk flow in N. luetkeana sieve tubes, and revealed the complexity of sieve tube structure, with branches, junctions and lateral connections. Microinjection into sieve elements proved comparatively easy. Pulsed rhodamine B injection enabled the determination of flow velocity in individual sieve elements, and the direct visualization of pressure-induced reversals of flow direction across sieve plates. The reversal of flow direction across sieve plates by pressurizing the downstream sieve element conclusively demonstrates that a critical requirement of the Münch theory is satisfied in kelp; no such evidence exists for tracheophytes. Because of the high tolerance of its sieve elements to experimental manipulation, N. luetkeana is a promising alternative to vascular plants for studying the fluid mechanics of sieve tube networks. © The Author 2016. Published by Oxford University Press on behalf of the Annals of Botany Company. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Development of Naphthalene PLIF for Visualizing Ablation Products From a Space Capsule Heat Shield

NASA Technical Reports Server (NTRS)

Combs, C. S.; Clemens, N. T.; Danehy, P. M.

2014-01-01

The Orion Multi-Purpose Crew Vehicle (MPCV) will use an ablative heat shield. To better design this heat shield and others that will undergo planetary entry, an improved understanding of the ablation process would be beneficial. Here, a technique developed at The University of Texas at Austin that uses planar laser-induced fluorescence (PLIF) of a low-temperature sublimating ablator (naphthalene) to enable visualization of the ablation products in a hypersonic flow is applied. Although high-temperature ablation is difficult and expensive to recreate in a laboratory environment, low-temperature sublimation creates a limited physics problem that can be used to explore ablation-product transport in a hypersonic flow-field. In the current work, a subscale capsule reentry vehicle model with a solid naphthalene heat shield has been tested in a Mach 5 wind tunnel. The PLIF technique provides images of the spatial distribution of sublimated naphthalene in the heat-shield boundary layer, separated shear layer, and backshell recirculation region. Visualizations of the capsule shear layer using both naphthalene PLIF and Schlieren imaging compared favorably. PLIF images have shown high concentrations of naphthalene in the capsule separated flow region, intermittent turbulent structures on the heat shield surface, and interesting details of the capsule shear layer structure. It was shown that, in general, the capsule shear layer appears to be more unsteady at lower angels of attack. The PLIF images demonstrated that during a wind tunnel run, as the model heated up, the rate of naphthalene ablation increased, since the PLIF signal increased steadily over the course of a run. Additionally, the shear layer became increasingly unsteady over the course of a wind tunnel run, likely because of increased surface roughness but also possibly because of the increased blowing. Regions with a relatively low concentration of naphthalene were also identified in the capsule backshell recirculation region and are most likely the result of cross-flow-induced vortices on the capsule afterbody.

Radiant energy absorption studies for laser propulsion. [gas dynamics

NASA Technical Reports Server (NTRS)

Caledonia, G. E.; Wu, P. K. S.; Pirri, A. N.

1975-01-01

A study of the energy absorption mechanisms and fluid dynamic considerations for efficient conversion of high power laser radiation into a high velocity flow is presented. The objectives of the study are: (1) to determine the most effective absorption mechanisms for converting laser radiation into translational energy, and (2) to examine the requirements for transfer of the absorbed energy into a steady flow which is stable to disturbances in the absorption zone. A review of inverse Bremsstrahlung, molecular and particulate absorption mechanisms is considered and the steady flow and stability considerations for conversion of the laser power to a high velocity flow in a nozzle configuration is calculated. A quasi-one-dimensional flow through a nozzle was formulated under the assumptions of perfect gas.

YAG Laser Vitreolysis vs Sham YAG Vitreolysis for Symptomatic Vitreous Floaters: A Randomized Clinical Trial.

PubMed

Shah, Chirag P; Heier, Jeffrey S

2017-09-01

Vitreous floaters are common and can worsen visual quality. YAG vitreolysis is an untested treatment for floaters. To evaluate YAG laser vitreolysis vs sham vitreolysis for symptomatic Weiss ring floaters from posterior vitreous detachment. This single-center, masked, sham-controlled randomized clinical trial was performed from March 25, 2015, to August 3, 2016, in 52 eyes of 52 patients (36 cases and 16 controls) treated at a private ophthalmology practice. Patients were randomly assigned to YAG laser vitreolysis or sham YAG (control). Primary 6-month outcomes were subjective change measured from 0% to 100% using a 10-point visual disturbance score, a 5-level qualitative scale, and National Eye Institute Visual Functioning Questionnaire 25 (NEI VFQ-25). Secondary outcomes included objective change assessed by masked grading of color fundus photography and Early Treatment Diabetic Retinopathy Study best-corrected visual acuity. Fifty-two patients (52 eyes; 17 men and 35 women; 51 white and 1 Asian) with symptomatic Weiss rings were enrolled in the study (mean [SD] age, 61.4 [8.0] years for the YAG laser group and 61.1 [6.6] years for the sham group). The YAG laser group reported greater symptomatic improvement (54%) than controls (9%) (difference, 45%; 95% CI, 25%-64%; P < .001). In the YAG laser group, the 10-point visual disturbance score improved by 3.2 vs 0.1 in the sham group (difference, -3.0; 95% CI, -4.3 to -1.7; P < .001). A total of 19 patients (53%) in the YAG laser group reported significantly or completely improved symptoms vs 0 individuals in the sham group (difference, 53%; 95% CI, 36%-69%, P < .001). Compared with sham, NEI VFQ-25 revealed improved general vision (difference, 16.3; 95% CI, 0.9-31.7; P = .04), peripheral vision (difference, 11.6; 95% CI, 0.8-22.4; P = .04), role difficulties (difference, 17.3; 95% CI, 8.0-26.6; P < .001), and dependency (difference, 5.6; 95% CI, 0.5-10.8; P = .03) among the YAG laser group. Best-corrected visual acuity changed by -0.2 letters in the YAG laser group and by -0.6 letters in sham group (difference, 0.4; 95% CI, -6.5 to 5.3; P = .94). No differences in adverse events between groups were identified. YAG laser vitreolysis subjectively improved Weiss ring-related symptoms and objectively improved Weiss ring appearance. Greater confidence in these outcomes may result from larger confirmatory studies of longer duration. clinicaltrials.gov NCT02897583.

Liquid Fuels: Pyrolytic Degradation and Fire Spread Behavior as Influenced by Buoyancy

NASA Technical Reports Server (NTRS)

Ross, Howard D. (Technical Monitor); Yeboah, Yaw D.

2003-01-01

This project was conducted by the Combustion and Emission Control Lab in the Engineering Department at Clark Atlanta University under NASA Grant No. NCC3-707. The work aimed at providing data to supplement the ongoing NASA research activities on flame spread across liquid pools by providing flow visualization and velocity measurements especially in the gas phase and gas-liquid interface. During this investigation, the detailed physics of flame spread across liquid pools was revealed using particle image velocimetry (PIV), 3-dimensional Laser Doppler velocimetry (LDV) and high-speed video imaging system (HSVS). Flow fields (front and side views) of both the liquid and gas phases were visually investigated for the three subflash regimes of flame spread behavior. Some interesting findings obtained from the front and side views on flame spread across butanol pools are presented. PIV results showed the size of the transient vortex in the liquid phase near the flame front varied with the initial pool temperature. The transient vortex ahead of the flame front in the gas phase was, for the first time, clearly observed located just within 0-3 mm above the liquid surface and its size was dependent on the initial pool temperature. We calculated the flow velocity at 1 mm below the liquid surface near the flame front and inferred the generation mechanism of the vortex in the gas phase. Finally, after comparison of the flow velocity of the liquid surface and the flame spread rate, a reasonable explanation to the formation mechanism of the pulsating characteristic was proposed. This explanation is compatible with the previous numerical calculations and deductions.

Stratified charge rotary engine combustion studies

NASA Technical Reports Server (NTRS)

Shock, H.; Hamady, F.; Somerton, C.; Stuecken, T.; Chouinard, E.; Rachal, T.; Kosterman, J.; Lambeth, M.; Olbrich, C.

1989-01-01

Analytical and experimental studies of the combustion process in a stratified charge rotary engine (SCRE) continue to be the subject of active research in recent years. Specifically to meet the demand for more sophisticated products, a detailed understanding of the engine system of interest is warranted. With this in mind the objective of this work is to develop an understanding of the controlling factors that affect the SCRE combustion process so that an efficient power dense rotary engine can be designed. The influence of the induction-exhaust systems and the rotor geometry are believed to have a significant effect on combustion chamber flow characteristics. In this report, emphasis is centered on Laser Doppler Velocimetry (LDV) measurements and on qualitative flow visualizations in the combustion chamber of the motored rotary engine assembly. This will provide a basic understanding of the flow process in the RCE and serve as a data base for verification of numerical simulations. Understanding fuel injection provisions is also important to the successful operation of the stratified charge rotary engine. Toward this end, flow visualizations depicting the development of high speed, high pressure fuel jets are described. Friction is an important consideration in an engine from the standpoint of lost work, durability and reliability. MSU Engine Research Laboratory efforts in accessing the frictional losses associated with the rotary engine are described. This includes work which describes losses in bearing, seal and auxillary components. Finally, a computer controlled mapping system under development is described. This system can be used to map shapes such as combustion chamber, intake manifolds or turbine blades accurately.

Stratified charge rotary engine combustion studies

NASA Astrophysics Data System (ADS)

Shock, H.; Hamady, F.; Somerton, C.; Stuecken, T.; Chouinard, E.; Rachal, T.; Kosterman, J.; Lambeth, M.; Olbrich, C.

1989-07-01

Analytical and experimental studies of the combustion process in a stratified charge rotary engine (SCRE) continue to be the subject of active research in recent years. Specifically to meet the demand for more sophisticated products, a detailed understanding of the engine system of interest is warranted. With this in mind the objective of this work is to develop an understanding of the controlling factors that affect the SCRE combustion process so that an efficient power dense rotary engine can be designed. The influence of the induction-exhaust systems and the rotor geometry are believed to have a significant effect on combustion chamber flow characteristics. In this report, emphasis is centered on Laser Doppler Velocimetry (LDV) measurements and on qualitative flow visualizations in the combustion chamber of the motored rotary engine assembly. This will provide a basic understanding of the flow process in the RCE and serve as a data base for verification of numerical simulations. Understanding fuel injection provisions is also important to the successful operation of the stratified charge rotary engine. Toward this end, flow visualizations depicting the development of high speed, high pressure fuel jets are described. Friction is an important consideration in an engine from the standpoint of lost work, durability and reliability. MSU Engine Research Laboratory efforts in accessing the frictional losses associated with the rotary engine are described. This includes work which describes losses in bearing, seal and auxillary components. Finally, a computer controlled mapping system under development is described. This system can be used to map shapes such as combustion chamber, intake manifolds or turbine blades accurately.

The physics of aerobreakup. IV. Strain-thickening liquids

NASA Astrophysics Data System (ADS)

Mitkin, V. V.; Theofanous, T. G.

2017-12-01

We extend our previous work on aerobreakup of Newtonian and viscoelastic-liquid drops to liquids of dense nanoparticle suspensions with strain-thickening rheology. As in the previous work, the scope includes the full range of aerodynamics, from near-incompressible to supersonic flows, covering all regimes of aerobreakup and employing laser-induced-fluorescence visualizations with μs/μm resolutions. The key physics of Rayleigh-Taylor piercing (1st criticality), Shear-Induced Entrainment (SIE, 2nd criticality), and Kelvin-Helmholtz SIE (3rd criticality) are verified and quantified on the same scaling/theoretical approach as in our previous work but with modifications that account for the rheology of these liquids.

Visual System Neural Responses to Laser Exposure from Local Q-Switched Pulses and Extended Source CW Speckle Patterns.

DTIC Science & Technology

1985-09-30

layers of the retina as seen in retinitis pigmentosa (Wolbarsht & Landers, 1980; Stefansson et al, 1981 a). Those are all long-term effects with a delay...block numoer) FIELD GROUP SUB-GROUP retinal damage center-surround 20 05 laser injury cat retina 20 06 visual perception N02 anesthesia 19. ABSTRACT...Continue on reverse if necessary and identify by block number) The reports of retinal damage from exposure to short pulse laser energy without any

Modelling of fluid flow phenomenon in laser+GMAW hybrid welding of aluminum alloy considering three phase coupling and arc plasma shear stress

NASA Astrophysics Data System (ADS)

Xu, Guoxiang; Li, Pengfei; Cao, Qingnan; Hu, Qingxian; Gu, Xiaoyan; Du, Baoshuai

2018-03-01

The present study aims to develop a unified three dimensional numerical model for fiber laser+GMAW hybrid welding, which is used to study the fluid flow phenomena in hybrid welding of aluminum alloy and the influence of laser power on weld pool dynamic behavior. This model takes into account the coupling of gas, liquid and metal phases. Laser heat input is described using a cone heat source model with changing peak power density, its height being determined based on the keyhole size. Arc heat input is modeled as a double ellipsoid heat source. The arc plasma flow and droplet transfer are simulated through the two simplified models. The temperature and velocity fields for different laser powers are calculated. The computed results are in general agreement with the experimental data. Both the peak and average values of fluid flow velocity during hybrid welding are much higher than those of GMAW. At a low level of laser power, both the arc force and droplet impingement force play a relatively large role on fluid flow in the hybrid welding. Keyhole depth always oscillates within a range. With an increase in laser power, the weld pool behavior becomes more complex. An anti-clockwise vortex is generated and the stability of keyhole depth is improved. Besides, the effects of laser power on different driving forces of fluid flow in weld pool are also discussed.

Fluorescence Visualization of Hypersonic Flow over Rapid Prototype Wind-Tunnel Models

NASA Technical Reports Server (NTRS)

Alderfer, D. W.; Danehy, P. M.; Inma, J. A.; Berger, K. T.; Buck, G. M.; Schwartz, R J.

2007-01-01

Reentry models for use in hypersonic wind tunnel tests were fabricated using a stereolithography apparatus. These models were produced in one day or less, which is a significant time savings compared to the manufacture of ceramic or metal models. The models were tested in the NASA Langley Research Center 31-Inch Mach 10 Air Tunnel. Most of the models did not survive repeated tests in the tunnel, and several failure modes of the models were identified. Planar laser-induced fluorescence (PLIF) of nitric oxide (NO) was used to visualize the flowfields in the wakes of these models. Pure NO was either seeded through tubes plumbed into the model or via a tube attached to the strut holding the model, which provided localized addition of NO into the model s wake through a porous metal cylinder attached to the end of the tube. Models included several 2-inch diameter Inflatable Reentry Vehicle Experiment (IRVE) models and 5-inch diameter Crew Exploration Vehicle (CEV) models. Various configurations were studied including different sting placements relative to the models, different model orientations and attachment angles, and different NO seeding methods. The angle of attack of the models was also varied and the location of the laser sheet was scanned to provide three-dimensional flowfield information. Virtual Diagnostics Interface technology, developed at NASA Langley, was used to visualize the data sets in post processing. The use of calibration "dotcards" was investigated to correct for camera perspective and lens distortions in the PLIF images. Lessons learned and recommendations for future experiments are discussed.

Laser velocimeter application to oscillatory liquid flows

NASA Technical Reports Server (NTRS)

Gartrell, L. R.

1978-01-01

A laser velocimeter technique was used to measure the mean velocity and the frequency characteristics of an oscillatory flow component generated with a rotating flapper in liquid flow system at Reynolds numbers approximating 93,000. The velocity information was processed in the frequency domain using a tracker whose output was used to determine the flow spectrum. This was accomplished with the use of an autocorrelator/Fourier transform analyzer and a spectrum averaging analyzer where induced flow oscillations up to 40 Hz were detected. Tests were conducted at a mean flow velocity of approximately 2 m/s. The experimental results show that the laser velocimeter can provide quantitative information such as liquid flow velocity and frequency spectrum with a possible application to cryogenic fluid flows.

Design of "model-friendly" turbulent non-premixed jet burners for C2+ hydrocarbon fuels

NASA Astrophysics Data System (ADS)

Zhang, Jiayao; Shaddix, Christopher R.; Schefer, Robert W.

2011-07-01

Experimental measurements in laboratory-scale turbulent burners with well-controlled boundary and flow configurations can provide valuable data for validating models of turbulence-chemistry interactions applicable to the design and analysis of practical combustors. This paper reports on the design of two canonical nonpremixed turbulent jet burners for use with undiluted gaseous and liquid hydrocarbon fuels, respectively. Previous burners of this type have only been developed for fuels composed of H2, CO, and/or methane, often with substantial dilution. While both new burners are composed of concentric tubes with annular pilot flames, the liquid-fuel burner has an additional fuel vaporization step and an electrically heated fuel vapor delivery system. The performance of these burners is demonstrated by interrogating four ethylene flames and one flame fueled by a simple JP-8 surrogate. Through visual observation, it is found that the visible flame lengths show good agreement with standard empirical correlations. Rayleigh line imaging demonstrates that the pilot flame provides a spatially homogeneous flow of hot products along the edge of the fuel jet. Planar imaging of OH laser-induced fluorescence reveals a lack of local flame extinction in the high-strain near-burner region for fuel jet Reynolds numbers (Re) less than 20 000, and increasingly common extinction events for higher jet velocities. Planar imaging of soot laser-induced incandescence shows that the soot layers in these flames are relatively thin and are entrained into vortical flow structures in fuel-rich regions inside of the flame sheet.

Fast-axial turbulent flow CO2 laser output characteristics and scaling parameters

NASA Astrophysics Data System (ADS)

Dembovetsky, V. V.; Zavalova, Valentina Y.; Zavalov, Yuri N.

1996-04-01

The paper presents the experimental results of evaluating the output characteristics of TLA- 600 carbon-dioxide laser with axial turbulent gas flow, as well as the results of numerical modeling. The output characteristic and spatial distribution of laser beam were measured with regard to specific energy input, working mixture pressure, active media length and output mirror reflection. The paper presents the results of experimental and theoretical study and design decisions on a succession of similar type industrial carbon-dioxide lasers with fast-axial gas-flow and dc discharge excitation of active medium developed at NICTL RAN. As an illustration, characteristics of the TLA-600 laser are cited.

Flowing Air-Water Cooled Slab Nd: Glass Laser

NASA Astrophysics Data System (ADS)

Lu, Baida; Cai, Bangwei; Liao, Y.; Xu, Shifa; Xin, Z.

1989-03-01

A zig-zag optical path slab geometry Nd: glass laser cooled through flowing air-water is developed by us. Theoretical studies on temperature distribution of slab and rod configurations in the unsteady state clarify the advantages of the slab geometry laser. The slab design and processing are also reported. In our experiments main laser output characteristics, e. g. laser efficiency, polarization, far-field divergence angle as well as resonator misalignment are investigated. The slab phosphate glass laser in combination with a crossed Porro-prism resonator demonstrates a good laser performance.

A model for a continuous-wave iodine laser

NASA Technical Reports Server (NTRS)

Hwang, In H.; Tabibi, Bagher M.

1990-01-01

A model for a continuous-wave (CW) iodine laser has been developed and compared with the experimental results obtained from a solar-simulator-pumped CW iodine laser. The agreement between the calculated laser power output and the experimental results is generally good for various laser parameters even when the model includes only prominent rate coefficients. The flow velocity dependence of the output power shows that the CW iodine laser cannot be achieved with a flow velocity below 1 m/s for the present solar-simulator-pumped CW iodine laser system.

Flow tube used to cool solar-pumped laser

NASA Technical Reports Server (NTRS)

1968-01-01

A flow tube has been designed and constructed to provide two major functions in the application of a laser beam for transmission of both sound and video. It maintains the YAG laser at the proper operating temperature of 300 degrees K under solar pumping conditions, and it serves as a pump cavity for the laser crystal.

Developments in flow visualization methods for flight research

NASA Technical Reports Server (NTRS)

Holmes, Bruce J.; Obara, Clifford J.; Manuel, Gregory S.; Lee, Cynthia C.

1990-01-01

With the introduction of modern airplanes utilizing laminar flow, flow visualization has become an important diagnostic tool in determining aerodynamic characteristics such as surface flow direction and boundary-layer state. A refinement of the sublimating chemical technique has been developed to define both the boundary-layer transition location and the transition mode. In response to the need for flow visualization at subsonic and transonic speeds and altitudes above 20,000 feet, the liquid crystal technique has been developed. A third flow visualization technique that has been used is infrared imaging, which offers non-intrusive testing over a wide range of test conditions. A review of these flow visualization methods and recent flight results is presented for a variety of modern aircraft and flight conditions.

Hierarchical streamline bundles.

PubMed

Yu, Hongfeng; Wang, Chaoli; Shene, Ching-Kuang; Chen, Jacqueline H

2012-08-01

Effective 3D streamline placement and visualization play an essential role in many science and engineering disciplines. The main challenge for effective streamline visualization lies in seed placement, i.e., where to drop seeds and how many seeds should be placed. Seeding too many or too few streamlines may not reveal flow features and patterns either because it easily leads to visual clutter in rendering or it conveys little information about the flow field. Not only does the number of streamlines placed matter, their spatial relationships also play a key role in understanding the flow field. Therefore, effective flow visualization requires the streamlines to be placed in the right place and in the right amount. This paper introduces hierarchical streamline bundles, a novel approach to simplifying and visualizing 3D flow fields defined on regular grids. By placing seeds and generating streamlines according to flow saliency, we produce a set of streamlines that captures important flow features near critical points without enforcing the dense seeding condition. We group spatially neighboring and geometrically similar streamlines to construct a hierarchy from which we extract streamline bundles at different levels of detail. Streamline bundles highlight multiscale flow features and patterns through clustered yet not cluttered display. This selective visualization strategy effectively reduces visual clutter while accentuating visual foci, and therefore is able to convey the desired insight into the flow data.

Effects of forebody strakes and Mach number on overall aerodynamic characteristics of configuration with 55 deg cropped delta wing

NASA Technical Reports Server (NTRS)

Erickson, Gary E.; Rogers, Lawrence W.

1992-01-01

A wind tunnel data base was established for the effects of chine-like forebody strakes and Mach number on the longitudinal and lateral-directional characteristics of a generalized 55 degree cropped delta wing-fuselage-centerline vertical tail configuration. The testing was conducted in the 7- by 10-Foot Transonic Tunnel at the David Taylor Research Center at free-stream Mach numbers of 0.40 to 1.10 and Reynolds numbers based on the wing mean aerodynamic chord of 1.60 x 10(exp 6) to 2.59 x 10(exp 6). The best matrix included angles of attack from 0 degree to a maximum of 28 degree, angles of sidesip of 0, +5, and -5 degrees, and wing leading-edge flat deflection angles of 0 and 30 degrees. Key flow phenomena at subsonic and transonic conditions were identified by measuring off-body flow visualization with a laser screen technique. These phenomena included coexisting and interacting vortex flows and shock waves, vortex breakdown, vortex flow interactions with the vertical tail, and vortices induced by flow separation from the hinge line of the deflected wing flap. The flow mechanisms were correlated with the longitudinal and lateral-directional aerodynamic data trends.

Understanding Subsurface Colloid Behavior: A New Visualization Technique and the Application of Geo-Centrifuge Modeling

NASA Astrophysics Data System (ADS)

Yoon, J. S.; Culligan, P. J.; Germaine, J. T.

2003-12-01

Subsurface colloid behavior has recently drawn attention because colloids are suspected of enhancing contaminant transport in groundwater systems. To better understand the processes by which colloids move through the subsurface, and in particular the vadose zone, a new technique that enables real-time visualization of colloid particles as they move through a porous medium has been developed. This visualization technique involves the use of laser induced fluorescent particles and digital image processing to directly observe particles moving through a porous medium consisting of soda-lime glass beads and water in a transparent experimental box of 10.0cm\\x9D27.9cm\\x9D2.38cm. Colloid particles are simulated using commercially available micron sized particles that fluoresce under argon-ion laser light. The fluorescent light given off from the particles is captured through a camera filter, which lets through only the emitted wavelength of the colloid particles. The intensity of the emitted light is proportional to the colloid particle concentration. The images of colloid movement are captured by a MagnaFire digital camera; a cooled CCD digital camera produced by Optronics. This camera enables real-time capture of images to a computer, thereby allowing the images to be processed immediately. The images taken by the camera are analyzed by the ImagePro software from Media Cybernetics, which contains a range of counting, sizing, measuring, and image enhancement tools for image processing. Laboratory experiments using the new technique have demonstrated the existence of both irreversible and reversible sites for colloid entrapment during uniform saturated flow in a homogeneous porous medium. These tests have also shown a dependence of colloid entrapment on velocity. Models for colloid transport currently available in the literature have proven to be inadequate predictors for the experimental observations, despite the simplicity of the system studied. To further extend the work, the visualization technique has been developed for use on the geo-centrifuge. The advantage that the geo-centrifuge has for investigating subsurface colloid behavior, is the ability to simulate unsaturated transport mechanisms under well simulated field moisture profiles and in shortened periods of time. A series of tests to investigate colloid transport during uniform saturated flow is being used to examine basic scaling laws for colloid transport under enhanced gravity. The paper will describe the new visualization technique, its use in geo-centrifuge testing and observations on scaling relationships for colloid transport during geo-centrifuge experiments. Although the visualization technique has been developed for investigating subsurface colloid behavior, it does have application in other areas of investigation, including the investigation of microbial behavior in the subsurface.

Flow visualization techniques for flight research

NASA Technical Reports Server (NTRS)

Fisher, David F.; Meyer, Robert R., Jr.

1989-01-01

In-flight flow visualization techniques used at the Dryden Flight Research Facility of NASA Ames Research Center (Ames-Dryden) and its predecessor organizations are described. Results from flight tests which visualized surface flows using flow cones, tufts, oil flows, liquid crystals, sublimating chemicals, and emitted fluids were obtained. Off-surface flow visualization of vortical flow was obtained from natural condensation and two methods using smoke generator systems. Recent results from flight tests at NASA Langley Research Center using a propylene glycol smoker and an infrared imager are also included. Results from photo-chase aircraft, onboard and postflight photography are presented.

Flow Visualization Techniques for Flight Research

NASA Technical Reports Server (NTRS)

Fisher, David F.; Meyer, Robert R., Jr.

1988-01-01

In-flight flow visualization techniques used at the Dryden Flight Research Facility of NASA Ames Research Center (Ames-Dryden) and its predecessor organizations are described. Results from flight tests which visualized surface flows using flow cones, tufts, oil flows, liquid crystals, sublimating chemicals, and emitted fluids have been obtained. Off-surface flow visualization of vortical flow has been obtained from natural condensation and two methods using smoke generator systems. Recent results from flight tests at NASA Langley Research Center using a propylene glycol smoker and an infrared imager are also included. Results from photo-chase aircraft, onboard and postflight photography are presented.

Single-shot lifetime-based PSP and TSP measurements on turbocharger compressor blades

NASA Astrophysics Data System (ADS)

Peng, Di; Jiao, Lingrui; Yu, Yuelong; Liu, Yingzheng; Oshio, Tetsuya; Kawakubo, Tomoki; Yakushiji, Akimitsu

2017-09-01

Fast-responding pressure-sensitive paint (Fast PSP) and temperature-sensitive paint (TSP) measurements were conducted on two turbocharger compressors using a single-shot lifetime-based technique. The fast PSP and TSP were applied on separate blades of one compressor, and both paints were excited by a pulsed 532 nm Nd:YAG laser. The luminescent decay signals following the laser pulse were recorded by a CCD camera in a double-exposure mode. Instantaneous pressure and temperature fields on compressor blades were obtained simultaneously, for rotation speeds up to 150,000 rpm. The variations in pressure and temperature fields with rotation speed, flow rate and runtime were clearly visualized, showing the advantage of high spatial resolution. Severe image blurring problems and significant temperature-induced errors in the PSP results were found at high rotation speeds. The first issue was addressed by incorporating a deconvolution-based deblurring algorithm to recover the clear image from the blurred image using the combination of luminescent lifetime and rotation speed. The second issue was resolved by applying a pixel-by-pixel temperature correction based on the TSP results. The current technique has shown great capabilities in flow diagnostics of turbomachinery and can serve as a powerful tool for CFD validations and design optimizations.

Switchable skin window induced by optical clearing method for dermal blood flow imaging

NASA Astrophysics Data System (ADS)

Wang, Jing; Shi, Rui; Zhu, Dan

2013-06-01

Optical imaging techniques have shown tremendous potential for assessing cutaneous microcirculation, but the imaging depth and contrast is limited by the strong scattering of skin. Current skin windows have to be fulfilled by surgical operation and suffer from some side effects. In this study, a switchable skin window was developed by topical application of an optical clearing agent (OCA) and saline on rat skin in vivo. The validity of the skin window was evaluated by the laser speckle contrast imaging technique, and the safety of OCA to the body was tested through histologic examinations. The results indicated that administration of OCA or saline on rat skin in vivo can open or close the window of skin repeatedly for three days. With the repair effect of hyaluronic acid and Vaseline, it is able to repeatedly visualize the dermal blood vessels and flow distribution. Long-term observation shows that there is no abnormal reflection in micro-structure, body weight, organ coefficients, histopathologic lesions, or toxic reactions compared with a control group. This switchable window will provide an effective tool not only for cutaneous microcirculation with laser speckle contrast imaging, but also for diagnosis and treatment of peripheral vascular diseases, including tumor research with various optical imaging techniques.

A compact tunable diode laser absorption spectrometer to monitor CO2 at 2.7 μm wavelength in hypersonic flows.

PubMed

Vallon, Raphäel; Soutadé, Jacques; Vérant, Jean-Luc; Meyers, Jason; Paris, Sébastien; Mohamed, Ajmal

2010-01-01

Since the beginning of the Mars planet exploration, the characterization of carbon dioxide hypersonic flows to simulate a spaceship's Mars atmosphere entry conditions has been an important issue. We have developed a Tunable Diode Laser Absorption Spectrometer with a new room-temperature operating antimony-based distributed feedback laser (DFB) diode laser to characterize the velocity, the temperature and the density of such flows. This instrument has been tested during two measurement campaigns in a free piston tunnel cold hypersonic facility and in a high enthalpy arc jet wind tunnel. These tests also demonstrate the feasibility of mid-infrared fiber optics coupling of the spectrometer to a wind tunnel for integrated or local flow characterization with an optical probe placed in the flow.

Personal computer (PC) based image processing applied to fluid mechanics research

NASA Technical Reports Server (NTRS)

Cho, Y.-C.; Mclachlan, B. G.

1987-01-01

A PC based image processing system was employed to determine the instantaneous velocity field of a two-dimensional unsteady flow. The flow was visualized using a suspension of seeding particles in water, and a laser sheet for illumination. With a finite time exposure, the particle motion was captured on a photograph as a pattern of streaks. The streak pattern was digitized and processsed using various imaging operations, including contrast manipulation, noise cleaning, filtering, statistical differencing, and thresholding. Information concerning the velocity was extracted from the enhanced image by measuring the length and orientation of the individual streaks. The fluid velocities deduced from the randomly distributed particle streaks were interpolated to obtain velocities at uniform grid points. For the interpolation a simple convolution technique with an adaptive Gaussian window was used. The results are compared with a numerical prediction by a Navier-Stokes commputation.

Personal Computer (PC) based image processing applied to fluid mechanics

NASA Technical Reports Server (NTRS)

Cho, Y.-C.; Mclachlan, B. G.

1987-01-01

A PC based image processing system was employed to determine the instantaneous velocity field of a two-dimensional unsteady flow. The flow was visualized using a suspension of seeding particles in water, and a laser sheet for illumination. With a finite time exposure, the particle motion was captured on a photograph as a pattern of streaks. The streak pattern was digitized and processed using various imaging operations, including contrast manipulation, noise cleaning, filtering, statistical differencing, and thresholding. Information concerning the velocity was extracted from the enhanced image by measuring the length and orientation of the individual streaks. The fluid velocities deduced from the randomly distributed particle streaks were interpolated to obtain velocities at uniform grid points. For the interpolation a simple convolution technique with an adaptive Gaussian window was used. The results are compared with a numerical prediction by a Navier-Stokes computation.

Wake Geometry Measurements and Analytical Calculations on a Small-Scale Rotor Model

NASA Technical Reports Server (NTRS)

Ghee, Terence A.; Berry, John D.; Zori, Laith A. J.; Elliott, Joe W.

1996-01-01

An experimental investigation was conducted in the Langley 14- by 22-Foot Subsonic Tunnel to quantify the rotor wake behind a scale model helicopter rotor in forward level flight at one thrust level. The rotor system in this test consisted of a four-bladed fully articulated hub with blades of rectangular planform and an NACA 0012 airfoil section. A laser light sheet, seeded with propylene glycol smoke, was used to visualize the vortex geometry in the flow in planes parallel and perpendicular to the free-stream flow. Quantitative measurements of wake geometric proper- ties, such as vortex location, vertical skew angle, and vortex particle void radius, were obtained as well as convective velocities for blade tip vortices. Comparisons were made between experimental data and four computational method predictions of experimental tip vortex locations, vortex vertical skew angles, and wake geometries. The results of these comparisons highlight difficulties of accurate wake geometry predictions.

Using the Freiburg Acuity and Contrast Test to measure visual performance in USAF personnel after PRK.

PubMed

Dennis, Richard J; Beer, Jeremy M A; Baldwin, J Bruce; Ivan, Douglas J; Lorusso, Frank J; Thompson, William T

2004-07-01

Photorefractive keratectomy (PRK) may be an alternative to spectacle and contact lens wear for United States Air Force (USAF) aircrew and may offer some distinct advantages in operational situations. However, any residual corneal haze or scar formation from PRK could exacerbate the disabling effects of a bright glare source on a complex visual task. The USAF recently completed a longitudinal clinical evaluation of the long-term effects of PRK on visual performance, including the experiment described herein. After baseline data were collected, 20 nonflying active duty USAF personnel underwent PRK. Visual performance was then measured at 6, 12, and 24 months after PRK. Visual acuity (VA) and contrast sensitivity (CS) data were collected by using the Freiburg Acuity and Contrast Test (FrACT), with the subject viewing half of the runs through a polycarbonate windscreen. Experimental runs were completed under 3 glare conditions: no glare source and with either a broadband or a green laser (532-nm) glare annulus (luminance approximately 6090 cd/m) surrounding the Landolt C stimulus. Systematic effects of PRK on VA relative to baseline were not identified. However, VA was almost 2 full Snellen lines worse with the laser glare source in place versus the broadband glare source. A significant drop-off was observed in CS performance after PRK under conditions of no glare and broadband glare; this was the case both with and without the windscreen. As with VA, laser glare disrupted CS performance significantly and more than broadband glare did. PRK does not appear to have affected VA, but the changes in CS might represent a true decline in visual performance. The greater disruptive effects from laser versus broadband glare may be a result of increased masking from coherent spatial noise (speckle) surrounding the laser stimulus.

Flow control about an airborne laser turret

NASA Astrophysics Data System (ADS)

Penix, L. E.

1982-06-01

This thesis project is the latest in a series of experiments conducted at the Naval Postgraduate School to improve the air flow in which a laser beam propagates. The particular turret to be studied is currently employed on Airborne Laser Laboratory which is aboard the NKC-135 aircraft; a one-third scale model was constructed in the 5 x 5 foot wind tunnel. The objective is to decrease the optical path distortion and jitter resulting from turbulent flow in the aft hemisphere of the turret that houses the laser telescope.

Effect of dorzolamide and timolol on ocular blood flow in patients with primary open angle glaucoma and ocular hypertension

PubMed Central

Fuchsjäger-Mayrl, G; Wally, B; Rainer, G; Buehl, W; Aggermann, T; Kolodjaschna, J; Weigert, G; Polska, E; Eichler, H-G; Vass, C; Schmetterer, L

2005-01-01

Background: There is evidence that perfusion abnormalities of the optic nerve head are involved in the pathogenesis of glaucoma. There is therefore considerable interest in the effects of topical antiglaucoma drugs on ocular blood flow. A study was undertaken to compare the ocular haemodynamic effects of dorzolamide and timolol in patients with primary open angle glaucoma (POAG) or ocular hypertension (OHT). Methods: One hundred and forty patients with POAG or OHT were included in a controlled, randomised, double blind study in two parallel groups; 70 were randomised to receive timolol and 70 to receive dorzolamide for a period of 6 months. Subjects whose intraocular pressure (IOP) did not respond to either of the two drugs were switched to the alternative treatment after 2 weeks. Scanning laser Doppler flowmetry was used to measure blood flow in the temporal neuroretinal rim and the cup of the optic nerve head. Pulsatile choroidal blood flow was assessed using laser interferometric measurement of fundus pulsation amplitude. Results: Five patients did not respond to timolol and were changed to the dorzolamide group, and 18 patients changed from dorzolamide treatment to timolol. The effects of both drugs on IOP and ocular perfusion pressure were comparable. Dorzolamide, but not timolol, increased blood flow in the temporal neuroretinal rim (8.5 (1.6)%, p<0.001 versus timolol) and the cup of the optic nerve head (13.5 (2.5)%, p<0.001 versus timolol), and fundus pulsation amplitude (8.9 (1.3)%, p<0.001 versus timolol). Conclusions: This study indicates augmented blood flow in the optic nerve head and choroid after 6 months of treatment with dorzolamide, but not with timolol. It remains to be established whether this effect can help to reduce visual field loss in patients with glaucoma. PMID:16170119

Analysis of UV-excited fluorochromes by flow cytometry using near-ultraviolet laser diodes.

PubMed

Telford, William G

2004-09-01

Violet laser diodes have become common and reliable laser sources for benchtop flow cytometers. While these lasers are very useful for a variety of violet and some ultraviolet-excited fluorochromes (e.g., DAPI), they do not efficiently excite most UV-stimulated probes. In this study, the next generation of InGaN near-UV laser diodes (NUVLDs) emitting in the 370-375-nm range have been evaluated as laser sources for cuvette-based flow cytometers. Several NUVLDs, ranging in wavelength from 370 to 374 nm and in power level from 1.5 to 10 mW, were mounted on a BD Biosciences LSR II and evaluated for their ability to excite cells labeled with the UV DNA binding dye DAPI, several UV phenotyping fluorochromes (including Alexa Fluor 350, Marina Blue, and quantum dots), and the fluorescent calcium chelator indo-1. NUVLDs at the 8-10-mW power range gave detection sensitivity levels comparable to more powerful solid-state and ion laser sources, using low-fluorescence microsphere beads as measurement standards. NUVLDs at all tested power levels allowed extremely high-resolution DAPI cell cycle analysis, and sources in the 8-10-mW power range excited Alexa Fluor 350, Marina Blue, and a variety of quantum dots at virtually the same signal-to-noise ratios as more powerful UV sources. These evaluations indicate that near-UV laser diodes installed on a cuvette-based flow cytometer performed nearly as well as more powerful solid-state UV lasers on the same instrumentation, and comparably to more powerful ion lasers on a jet-in-air system, and. Despite their limited power, integration of these small and inexpensive lasers into benchtop flow cytometers should allow the use of flow cytometric applications requiring UV excitation on a wide variety of instruments. Copyright 2004 Wiley-Liss, Inc.

A New Void Fraction Measurement Method for Gas-Liquid Two-Phase Flow in Small Channels

PubMed Central

Li, Huajun; Ji, Haifeng; Huang, Zhiyao; Wang, Baoliang; Li, Haiqing; Wu, Guohua

2016-01-01

Based on a laser diode, a 12 × 6 photodiode array sensor, and machine learning techniques, a new void fraction measurement method for gas-liquid two-phase flow in small channels is proposed. To overcome the influence of flow pattern on the void fraction measurement, the flow pattern of the two-phase flow is firstly identified by Fisher Discriminant Analysis (FDA). Then, according to the identification result, a relevant void fraction measurement model which is developed by Support Vector Machine (SVM) is selected to implement the void fraction measurement. A void fraction measurement system for the two-phase flow is developed and experiments are carried out in four different small channels. Four typical flow patterns (including bubble flow, slug flow, stratified flow and annular flow) are investigated. The experimental results show that the development of the measurement system is successful. The proposed void fraction measurement method is effective and the void fraction measurement accuracy is satisfactory. Compared with the conventional laser measurement systems using standard laser sources, the developed measurement system has the advantages of low cost and simple structure. Compared with the conventional void fraction measurement methods, the proposed method overcomes the influence of flow pattern on the void fraction measurement. This work also provides a good example of using low-cost laser diode as a competent replacement of the expensive standard laser source and hence implementing the parameter measurement of gas-liquid two-phase flow. The research results can be a useful reference for other researchers’ works. PMID:26828488

A New Void Fraction Measurement Method for Gas-Liquid Two-Phase Flow in Small Channels.

PubMed

Li, Huajun; Ji, Haifeng; Huang, Zhiyao; Wang, Baoliang; Li, Haiqing; Wu, Guohua

2016-01-27

Based on a laser diode, a 12 × 6 photodiode array sensor, and machine learning techniques, a new void fraction measurement method for gas-liquid two-phase flow in small channels is proposed. To overcome the influence of flow pattern on the void fraction measurement, the flow pattern of the two-phase flow is firstly identified by Fisher Discriminant Analysis (FDA). Then, according to the identification result, a relevant void fraction measurement model which is developed by Support Vector Machine (SVM) is selected to implement the void fraction measurement. A void fraction measurement system for the two-phase flow is developed and experiments are carried out in four different small channels. Four typical flow patterns (including bubble flow, slug flow, stratified flow and annular flow) are investigated. The experimental results show that the development of the measurement system is successful. The proposed void fraction measurement method is effective and the void fraction measurement accuracy is satisfactory. Compared with the conventional laser measurement systems using standard laser sources, the developed measurement system has the advantages of low cost and simple structure. Compared with the conventional void fraction measurement methods, the proposed method overcomes the influence of flow pattern on the void fraction measurement. This work also provides a good example of using low-cost laser diode as a competent replacement of the expensive standard laser source and hence implementing the parameter measurement of gas-liquid two-phase flow. The research results can be a useful reference for other researchers' works.

Laser Doppler flowmetry evaluation of gingival recovery response after laser treatment

NASA Astrophysics Data System (ADS)

Todea, Carmen; Cânjǎu, Silvana; Dodenciu, Dorin; Miron, Mariana I.; Tudor, Anca; Bǎlǎbuc, Cosmin

2013-06-01

This study was performed in order to evaluate in vivo the applicability of Laser Doppler Flowmetry (LDF) in recording the gingival blood flow and to assess the changes of gingival blood flow following gingival reshaping performed with Er:YAG and 980 nm diode lasers. The LDF evaluation was performed on 20 anterior teeth, which underwent reshaping of gingiva, corresponding to 5 female patients (4 anterior teeth/patient), aged between 20 and 35. One part of the mouth was treated with Er:YAG laser (LP, VLP modes, 140 - 250 mJ, 10 - 20 Hz, using cylindrical sapphire tips) and other part with 980 nm diode laser (CW, 4 W, contact mode and saline solution cooling). The gingival blood flow was monitored using a MoorLab laser Doppler equipment (Moor Instruments Ltd., Axminster, UK) with a straight optical probe, MP3b, 10 mm. The data were processed using statistical analysis software SPSS v16.0.1. The investigation showed an evident decrease in perfusion for both areas in comparison with the baseline values 24 hours after treatment. The microvascular blood flow increased significantly after 7 days in both areas but mostly in diode area (p<0.001). After 14 days for the Er:YAG area the blood perfusion returned to the initial value. The results in diode area remained at a high level after 14 days. Both lasers proved efficiency in the surgical treatment of gingival tissue. Moreover, Laser Doppler Flowmetry is adequate for recording changes in gingival blood flow following periodontal surgery.

Laser-ultrasonic inspection of hybrid laser-arc welded HSLA-65 steel

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lévesque, D.; Rousseau, G.; Monchalin, J.-P.

2014-02-18

The hybrid laser-arc welding (HLAW) process is a relatively low heat input joining technology that combines the synergistic qualities of both the high energy density laser beam for deep penetration and the arc for wide fit-up gap tolerance. This process is especially suitable for the shipbuilding industry where thick-gauge section, long steel plates have been widely used in a butt joint configuration. In this study, preliminary exploration was carried out to detect and visualize the welding defects using laser ultrasonics combined with the synthetic aperture focusing technique (SAFT). Results obtained on 9.3 mm thick butt-welded HSLA-65 steel plates indicated thatmore » the laser-ultrasonic SAFT inspection technique can successfully detect and visualize the presence of porosity, lack of fusion and internal crack defects. This was further confirmed by X-ray digital radiography and metallography. The results obtained clearly show the potential of using the laser-ultrasonic technology for the automated inspection of hybrid laser-arc welds.« less

Laser-ultrasonic inspection of hybrid laser-arc welded HSLA-65 steel

NASA Astrophysics Data System (ADS)

Lévesque, D.; Rousseau, G.; Wanjara, P.; Cao, X.; Monchalin, J.-P.

2014-02-01

The hybrid laser-arc welding (HLAW) process is a relatively low heat input joining technology that combines the synergistic qualities of both the high energy density laser beam for deep penetration and the arc for wide fit-up gap tolerance. This process is especially suitable for the shipbuilding industry where thick-gauge section, long steel plates have been widely used in a butt joint configuration. In this study, preliminary exploration was carried out to detect and visualize the welding defects using laser ultrasonics combined with the synthetic aperture focusing technique (SAFT). Results obtained on 9.3 mm thick butt-welded HSLA-65 steel plates indicated that the laser-ultrasonic SAFT inspection technique can successfully detect and visualize the presence of porosity, lack of fusion and internal crack defects. This was further confirmed by X-ray digital radiography and metallography. The results obtained clearly show the potential of using the laser-ultrasonic technology for the automated inspection of hybrid laser-arc welds.

Visual outcome of laser treatment in diabetic macular edema: Study from an Urban Diabetes Care Center.

PubMed

Alvi, Rashid; Memon, Muhammad Saleh; Shera, Samad; Mumtaz, Seema N; Shaikh, Sikander Ali; Fahim, Muhammad Faisal

2016-01-01

To determine the visual outcome of laser treatment in clinically significant macular edema. This interventional and qausi experimental study was carried out at Diabetic Association of Pakistan (DAP) during January 2011 and December 2012. Approval was taken from Research Ethical Committee of Isra Postgraduate Institute of Ophthalmology. Records of 925 eyes of 464 patients with "Clinical Significant macular edema" (CSME), treated with laser photocoagulation were analyzed. Best-corrected visual acuity (BCVA) at the time of presentation and at the last follow up, minimum of one year and maximum of 45 months was recorded and compared. SPSS version 20.0 was used to analyze the data. Diabetic retinopathy was found in 20.3% (1777) of 8742 diabetic attending DAP Hospital" amongst whom 39.6% (705) had Sight threatening diabetic retinopathy. Laser was advised in 96.4% (680) individuals, accepted by 70.5% (480) individuals. Amongst 960 eyes of 480 patients who accepted laser, 925 eyes had clinically significant macular edema and 35 eyes had PDR who are not included in this study. Amongst 925 eyes with CSME, Grid laser was done in 913 eyes (99%) and focal laser was done in 12 eyes (1%). After a follow up of 12 to 45 months, it was found that best corrected visual acuity had declined in 2.4% (22) eyes, stabilized in 67% (619) eyes and improved in 30.7% (284) eyes. One line improvement on Snellen's chart was fond in 21.3% (197) eyes, 2 lines in 8% (74) eyes, 3 lines in 1.2% (12) eyes and 4 lines in one (0.1%) eye with p-value of 0.000. Laser therapy is an effective treatment in stabilizing/improving the vision in diabetic macular edema particularly at those centers where only Argon Laser is available and OCF, FFA facilities do not exist.

Visual outcome of laser treatment in diabetic macular edema: Study from an Urban Diabetes Care Center

PubMed Central

Alvi, Rashid; Memon, Muhammad Saleh; Shera, Samad; Mumtaz, Seema N.; Shaikh, Sikander Ali; Fahim, Muhammad Faisal

2016-01-01

Objective: To determine the visual outcome of laser treatment in clinically significant macular edema. Methods: This interventional and qausi experimental study was carried out at Diabetic Association of Pakistan (DAP) during January 2011 and December 2012. Approval was taken from Research Ethical Committee of Isra Postgraduate Institute of Ophthalmology. Records of 925 eyes of 464 patients with “Clinical Significant macular edema” (CSME), treated with laser photocoagulation were analyzed. Best-corrected visual acuity (BCVA) at the time of presentation and at the last follow up, minimum of one year and maximum of 45 months was recorded and compared. SPSS version 20.0 was used to analyze the data. Results: Diabetic retinopathy was found in 20.3% (1777) of 8742 diabetic attending DAP Hospital” amongst whom 39.6% (705) had Sight threatening diabetic retinopathy. Laser was advised in 96.4% (680) individuals, accepted by 70.5% (480) individuals. Amongst 960 eyes of 480 patients who accepted laser, 925 eyes had clinically significant macular edema and 35 eyes had PDR who are not included in this study. Amongst 925 eyes with CSME, Grid laser was done in 913 eyes (99%) and focal laser was done in 12 eyes (1%). After a follow up of 12 to 45 months, it was found that best corrected visual acuity had declined in 2.4% (22) eyes, stabilized in 67% (619) eyes and improved in 30.7% (284) eyes. One line improvement on Snellen’s chart was fond in 21.3% (197) eyes, 2 lines in 8% (74) eyes, 3 lines in 1.2% (12) eyes and 4 lines in one (0.1%) eye with p-value of 0.000. Conclusion: Laser therapy is an effective treatment in stabilizing/improving the vision in diabetic macular edema particularly at those centers where only Argon Laser is available and OCF, FFA facilities do not exist. PMID:27882027

Advanced in Visualization of 3D Time-Dependent CFD Solutions

NASA Technical Reports Server (NTRS)

Lane, David A.; Lasinski, T. A. (Technical Monitor)

1995-01-01

Numerical simulations of complex 3D time-dependent (unsteady) flows are becoming increasingly feasible because of the progress in computing systems. Unfortunately, many existing flow visualization systems were developed for time-independent (steady) solutions and do not adequately depict solutions from unsteady flow simulations. Furthermore, most systems only handle one time step of the solutions individually and do not consider the time-dependent nature of the solutions. For example, instantaneous streamlines are computed by tracking the particles using one time step of the solution. However, for streaklines and timelines, particles need to be tracked through all time steps. Streaklines can reveal quite different information about the flow than those revealed by instantaneous streamlines. Comparisons of instantaneous streamlines with dynamic streaklines are shown. For a complex 3D flow simulation, it is common to generate a grid system with several millions of grid points and to have tens of thousands of time steps. The disk requirement for storing the flow data can easily be tens of gigabytes. Visualizing solutions of this magnitude is a challenging problem with today's computer hardware technology. Even interactive visualization of one time step of the flow data can be a problem for some existing flow visualization systems because of the size of the grid. Current approaches for visualizing complex 3D time-dependent CFD solutions are described. The flow visualization system developed at NASA Ames Research Center to compute time-dependent particle traces from unsteady CFD solutions is described. The system computes particle traces (streaklines) by integrating through the time steps. This system has been used by several NASA scientists to visualize their CFD time-dependent solutions. The flow visualization capabilities of this system are described, and visualization results are shown.

Weld pool development during GTA and laser beam welding of Type 304 stainless steel; Part I - theoretical analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zacharia, T.; David, S.A.; Vitek, J.M.

1989-12-01

A computational and experimental study was carried out to quantitatively understand the influence of the heat flow and the fluid flow in the transient development of the weld pool during gas tungsten arc (GTA) and laser beam welding of Type 304 stainless steel. Stationary gas tungsten arc and laser beam welds were made on two heats of Type 304 austenitic stainless steels containing 90 ppm sulfur and 240 ppm sulfur. A transient heat transfer model was utilized to simulate the heat flow and fluid flow in the weld pool. In this paper, the results of the heat flow and fluidmore » flow analysis are presented.« less

Velocity measurement in rocket exhaust and general aerodynamic flows by photolysis of H2O and laser induced fluorescence of OH

NASA Technical Reports Server (NTRS)

Boedeker, Laurence R.

1992-01-01

A 'tagging' approach in which the photolysis of H2O by an excimer laser creates a zone of enhanced OH concentration, while a second, pulsed-UV laser detects tagged-zone convection via time-delayed excitation of OH fluorescence, depends on the photodissociation process and the kinetics of OH decay (relative to velocity). For application to the fuel-rich, high supersonic Mach number exhaust flow of the SSME, the detection of OH is being accomplished with either a pulsed narrowband UV dye laser or a tunable XeCl excimer laser for excitation of an OH 0-0 band transition, while the two-photon photolysis of H2O is conducted by focusing an injection-locked KrF excimer laser into the flow.

Laser Doppler velocimetry using a modified computer mouse

NASA Astrophysics Data System (ADS)

Zaron, Edward D.

2016-10-01

A computer mouse has been modified for use as a low-cost laser Doppler interferometer and used to measure the two-component fluid velocity of a flowing soap film. The mouse sensor contains two vertical cavity surface emitting lasers, photodiodes, and signal processing hardware integrated into a single package, approximately 1 cm2 in size, and interfaces to a host computer via a standard USB port. Using the principle of self-mixing interferometry, whereby laser light re-enters the laser cavity after being scattered from a moving target, the Doppler shift and velocity of scatterers dispersed in the flow are measured. Observations of the boundary layer in a turbulent soap film channel flow demonstrate the capabilities of the sensor.

A study of the laminar separation bubble on an airfoil at low Reynolds numbers using flow visualization techniques

NASA Technical Reports Server (NTRS)

Schmidt, Gordon S.; Mueller, Thomas J.

1987-01-01

The use of flow visualization to study separation bubbles is evaluated. The wind tunnel, two NACA 66(3)-018 airfoil models, and kerosene vapor, titanium tetrachloride, and surface flow visualizations techniques are described. The application of the three visualization techniques to the two airfoil models reveals that the smoke and vapor techniques provide data on the location of laminar separation and the onset of transition, and the surface method produces information about the location of turbulent boundary layer separation. The data obtained with the three flow visualization techniques are compared to pressure distribution data and good correlation is detected. It is noted that flow visualization is an effective technique for examining separation bubbles.

Hydroxyl Tagging Velocimetry in a Mach 2 Flow With a Wall Cavity (Postprint)

DTIC Science & Technology

2005-01-01

tagging velocimetry (HTV) measurements of velocity were made in a Mach 2 flow with a wall cavity. In the HTV method, ArF excimer laser (193 nm) beams...is tracked by planar laser -induced fluorescence. The grid motion over a fixed time delay yields about 50 velocity vectors of the two-dimensional flow...Mach 2 flow with a wall cavity. In the HTV method, ArF excimer laser (193 nm) beams pass through a humid gas and dissociate H2O into H + OH to form

A Compact Tunable Diode Laser Absorption Spectrometer to Monitor CO2 at 2.7 μm Wavelength in Hypersonic Flows

PubMed Central

Vallon, Raphäel; Soutadé, Jacques; Vérant, Jean-Luc; Meyers, Jason; Paris, Sébastien; Mohamed, Ajmal

2010-01-01

Since the beginning of the Mars planet exploration, the characterization of carbon dioxide hypersonic flows to simulate a spaceship’s Mars atmosphere entry conditions has been an important issue. We have developed a Tunable Diode Laser Absorption Spectrometer with a new room-temperature operating antimony-based distributed feedback laser (DFB) diode laser to characterize the velocity, the temperature and the density of such flows. This instrument has been tested during two measurement campaigns in a free piston tunnel cold hypersonic facility and in a high enthalpy arc jet wind tunnel. These tests also demonstrate the feasibility of mid-infrared fiber optics coupling of the spectrometer to a wind tunnel for integrated or local flow characterization with an optical probe placed in the flow. PMID:22219703

Ocular injuries from laser accidents

NASA Astrophysics Data System (ADS)

Sliney, David H.

1996-04-01

Ocular injuries resulting from exposure to laser beams are relatively uncommon since there is normally a low probability of a relatively small-diameter laser beam entering the pupil of an eye. This has been the accident experience to date with lasers used in the research laboratory and in industry. A review of the accident data suggests that at least one type of laser is responsible for the majority of accidental injuries that result in a visual loss in the exposed eye. This is the q-switched neodymium:YAG laser. Although a continuous-wave laser causes a thermal coagulation of tissue, a q-switched laser having a pulse of only nanoseconds duration disrupts tissue. A visible or near-infrared laser can be focused on the retina, resulting in a vitreous hemorrhage. Examples of laser ocular injuries will be presented. Despite macular injuries and an initially serious visual loss, the vision of many patients recovers surprisingly well. Others may have severe vision loss. Corneal injuries resulting from exposure to reflected laser energy in the far-infrared account for surprisingly few reported laser accidents. The explanation for this accident statistic is not really clear. However, with the increasing use of lasers operating at many new wavelengths in the ultraviolet, visible and infrared, the ophthalmologist may see more accidental injuries from lasers.

Simultaneous visualization of water and hydrogen peroxide vapor using two-photon laser-induced fluorescence and photofragmentation laser-induced fluorescence.

PubMed

Larsson, Kajsa; Johansson, Olof; Aldén, Marcus; Bood, Joakim

2014-01-01

A concept based on a combination of photofragmentation laser-induced fluorescence (PF-LIF) and two-photon laser-induced fluorescence (LIF) is for the first time demonstrated for simultaneous detection of hydrogen peroxide (H2O2) and water (H2O) vapor. Water detection is based on two-photon excitation by an injection-locked krypton fluoride (KrF) excimer laser (248.28 nm), which induces broadband fluorescence (400-500 nm) from water. The same laser simultaneously photodissociates H2O2, whereupon the generated OH fragments are probed by LIF after a time delay of typically 50 ns, by a frequency-doubled dye laser (281.91 nm). Experiments in six different H2O2/H2O mixtures of known compositions show that both signals are linearly dependent on respective species concentration. For the H2O2 detection there is a minor interfering signal contribution from OH fragments created by two-photon photodissociation of H2O. Since the PF-LIF signal yield from H2O2 is found to be at least ∼24,000 times higher than the PF-LIF signal yield from H2O at room temperature, this interference is negligible for most H2O/H2O2 mixtures of practical interest. Simultaneous single-shot imaging of both species was demonstrated in a slightly turbulent flow. For single-shot imaging the minimum detectable H2O2 and H2O concentration is 10 ppm and 0.5%, respectively. The proposed measurement concept could be a valuable asset in several areas, for example, in atmospheric and combustion science and research on vapor-phase H2O2 sterilization in the pharmaceutical and aseptic food-packaging industries.

Diode laser to treat small oral vascular malformations: A prospective case series study.

PubMed

Bacci, Christian; Sacchetto, Luca; Zanette, Gastone; Sivolella, Stefano

2018-02-01

The current work examined a consecutive series of patients presenting vascular malformations (VMs) and venous lakes (VLs) of the lip and oral mucosa who were treated with transmucosal diode laser applications and assessed over a 1 year period. Fifty-nine patients (31 males and 28 females) presenting low-flow VMs or VLs of the oral cavity were treated transmucosally using a diode laser (with an 830 nm operating wavelength and 1.6 W output power) with a 320 µm diameter flexible fiber. All the lesions were assessed 7 days, 30 days, and 1 year after the laser treatment, and the lesion reduction percentage was scored on a one to five scale. The patients were also asked to assess their pain perception daily during the 7 days following the treatment using a visual analog scale (VAS). There were no procedure-related intra- or post-operative complications; only modest pain intensity was reported. Thirty days after the treatment, lesion reduction was described as excellent or good in 52 cases; it was fair or poor in 7. Six patients (F:M ratio 2:4) required a second diode laser application. At the 1 year follow-up, volume reduction was complete in 48 out of 59 patients; there were five recurrences (F:M ratio 3:2). No relevant gender-related differences were noted. The use of diode laser application to treat small oral VMs and VLs was associated to shorter operating times and fewer postoperative complications with respect to the scapel surgery approach. More than one session may nevertheless be required if the anomaly is larger than 10 mm. Lasers Surg. Med. 50:111-116, 2018. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

Computational fluid dynamics assisted characterization of parafoveal hemodynamics in normal and diabetic eyes using adaptive optics scanning laser ophthalmoscopy.

PubMed

Lu, Yang; Bernabeu, Miguel O; Lammer, Jan; Cai, Charles C; Jones, Martin L; Franco, Claudio A; Aiello, Lloyd Paul; Sun, Jennifer K

2016-12-01

Diabetic retinopathy (DR) is the leading cause of visual loss in working-age adults worldwide. Previous studies have found hemodynamic changes in the diabetic eyes, which precede clinically evident pathological alterations of the retinal microvasculature. There is a pressing need for new methods to allow greater understanding of these early hemodynamic changes that occur in DR. In this study, we propose a noninvasive method for the assessment of hemodynamics around the fovea (a region of the eye of paramount importance for vision). The proposed methodology combines adaptive optics scanning laser ophthalmoscopy and computational fluid dynamics modeling. We compare results obtained with this technique with in vivo measurements of blood flow based on blood cell aggregation tracking. Our results suggest that parafoveal hemodynamics, such as capillary velocity, wall shear stress, and capillary perfusion pressure can be noninvasively and reliably characterized with this method in both healthy and diabetic retinopathy patients.

Computational fluid dynamics assisted characterization of parafoveal hemodynamics in normal and diabetic eyes using adaptive optics scanning laser ophthalmoscopy

PubMed Central

Lu, Yang; Bernabeu, Miguel O.; Lammer, Jan; Cai, Charles C.; Jones, Martin L.; Franco, Claudio A.; Aiello, Lloyd Paul; Sun, Jennifer K.

2016-01-01

Diabetic retinopathy (DR) is the leading cause of visual loss in working-age adults worldwide. Previous studies have found hemodynamic changes in the diabetic eyes, which precede clinically evident pathological alterations of the retinal microvasculature. There is a pressing need for new methods to allow greater understanding of these early hemodynamic changes that occur in DR. In this study, we propose a noninvasive method for the assessment of hemodynamics around the fovea (a region of the eye of paramount importance for vision). The proposed methodology combines adaptive optics scanning laser ophthalmoscopy and computational fluid dynamics modeling. We compare results obtained with this technique with in vivo measurements of blood flow based on blood cell aggregation tracking. Our results suggest that parafoveal hemodynamics, such as capillary velocity, wall shear stress, and capillary perfusion pressure can be noninvasively and reliably characterized with this method in both healthy and diabetic retinopathy patients. PMID:28078170

LASER APPLICATIONS AND OTHER TOPICS IN QUANTUM ELECTRONICS: Laser Doppler visualisation of the velocity field by excluding the influence of multiparticle scattering

NASA Astrophysics Data System (ADS)

Dubnishchev, Yu N.; Chugui, Yu V.; Kompenhans, J.

2009-10-01

The method of laser Doppler visualisation and measurement of the velocity field in gas and liquid flows by suppressing the influence of multiparticle scattering is discussed. The cross section of the flow under study is illuminated by a laser beam transformed by an anamorphic optical system into a laser sheet. The effect of multiparticle scattering is eliminated by obtaining differential combinations of frequency-demodulated images of the laser sheet in different regions of the angular spectrum of scattered light.

Efficacy and perioperative timing of bromfenac in the management of ocular discomfort after femtosecond laser-assisted laser in situ keratomileusis.

PubMed

Cleaveland, Nathan A; De Mann, Derek W; Carlson, Neil E; Keil, Michael L

2017-02-01

To evaluate the safety, efficacy, and appropriate perioperative timing of the use of topical bromfenac ophthalmic solution 0.07% after femtosecond laser-assisted laser in situ keratomileusis (LASIK). Keil LASIK Vision Center, Grand Rapids, Michigan, USA. Prospective case series. Ocular discomfort was assessed 1, 2, and 5 hours postoperatively and the following morning using the Ocular Comfort Grading Assessment in patients treated with topical bromfenac 0.07% or artificial tears just before, just after, or before and after femtosecond laser-assisted LASIK. Visual outcomes and complications were noted up to 24 hours. The study enrolled 64 patients (120 eyes). Patients who were treated with bromfenac 0.07% just before or before and after femtosecond laser-assisted LASIK showed the greatest statistically significant decrease in several discomfort scores within the first few hours in comparison with the control group. Two hours after surgery, the majority of patients who were treated before and after LASIK were sleeping comfortably. There were no significant differences in visual acuity; 1 day postoperatively, the uncorrected distance visual acuity was 20/20 in 106 eyes (89%) and 20/25 or better in 116 eyes (97%). At 3 months, all patients had binocular distance visual acuity of 20/20 or better and 86% of patients had 20/15 or better. Ocular discomfort after femtosecond laser-assisted LASIK was reduced with a single dose of topical bromfenac 0.07% given immediately before surgery or given just before and after surgery and was typically minimal in all groups the morning after surgery. Copyright © 2017 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

Remote Infrared Thermography for In-Flight Flow Diagnostics

NASA Technical Reports Server (NTRS)

Shiu, H. J.; vanDam, C. P.

1999-01-01

The feasibility of remote in-flight boundary layer visualization via infrared in incompressible flow was established in earlier flight experiments. The past year's efforts focused on refining and determining the extent and accuracy of this technique of remote in-flight flow visualization via infrared. Investigations were made into flow separation visualization, visualization at transonic conditions, shock visualization, post-processing to mitigate banding noise in the NITE Hawk's thermograms, and a numeric model to predict surface temperature distributions. Although further flight tests are recommended, this technique continues to be promising.

Effect of Thickness-to-Chord Ratio on Flow Structure of Low Swept Delta Wing

NASA Astrophysics Data System (ADS)

Gulsacan, Burak; Sencan, Gizem; Yavuz, Mehmet Metin

2017-11-01

The effect of thickness-to-chord (t/C) ratio on flow structure of a delta wing with sweep angle of 35 degree is characterized in a low speed wind tunnel using laser illuminated smoke visualization, particle image velocimetry, and surface pressure measurements. Four different t/C ratio varying from 4.75% to 19% are tested at angles of attack 4, 6, 8, and 10 degrees for Reynolds numbers Re =10,000 and 35,000. The results indicate that the effect of thickness-to-chord ratio on flow structure is quite substantial, such that, as the wing thickness increases, the flow structure transforms from leading edge vortex to three-dimensional separated flow regime. The wing with low t/C ratio of 4.75% experiences pronounced surface separation at significantly higher angle of attack compared to the wing with high t/C ratio. The results might explain some of the discrepancies reported in previously conducted studies related to delta wings. In addition, it is observed that the thickness of the shear layer separated from windward side of the wing is directly correlated with the thickness of the wing. To conclude, the flow structure on low swept delta wing is highly affected by t/C ratio, which in turn might indicate the potential usage of wing thickness as an effective flow control parameter.

Magnetic resonance imaging of convection in laser-polarized xenon

NASA Technical Reports Server (NTRS)

Mair, R. W.; Tseng, C. H.; Wong, G. P.; Cory, D. G.; Walsworth, R. L.

2000-01-01

We demonstrate nuclear magnetic resonance (NMR) imaging of the flow and diffusion of laser-polarized xenon (129Xe) gas undergoing convection above evaporating laser-polarized liquid xenon. The large xenon NMR signal provided by the laser-polarization technique allows more rapid imaging than one can achieve with thermally polarized gas-liquid systems, permitting shorter time-scale events such as rapid gas flow and gas-liquid dynamics to be observed. Two-dimensional velocity-encoded imaging shows convective gas flow above the evaporating liquid xenon, and also permits the measurement of enhanced gas diffusion near regions of large velocity variation.

Measurements in the Turbulent Boundary Layer at Constant Pressure in Subsonic and Supersonic Flow. Part 2: Laser-Doppler Velocity Measurements

NASA Technical Reports Server (NTRS)

Dimotakis, P. E.; Collins, D. J.; Lang, D. B.

1979-01-01

A description of both the mean and the fluctuating components of the flow, and of the Reynolds stress as observed using a dual forward scattering laser-Doppler velocimeter is presented. A detailed description of the instrument and of the data analysis techniques were included in order to fully document the data. A detailed comparison was made between the laser-Doppler results and those presented in Part 1, and an assessment was made of the ability of the laser-Doppler velocimeter to measure the details of the flows involved.

Wireless ultrasonic wavefield imaging via laser for hidden damage detection inside a steel box girder bridge

NASA Astrophysics Data System (ADS)

An, Yun-Kyu; Song, Homin; Sohn, Hoon

2014-09-01

This paper presents a wireless ultrasonic wavefield imaging (WUWI) technique for detecting hidden damage inside a steel box girder bridge. The proposed technique allows (1) complete wireless excitation of piezoelectric transducers and noncontact sensing of the corresponding responses using laser beams, (2) autonomous damage visualization without comparing against baseline data previously accumulated from the pristine condition of a target structure and (3) robust damage diagnosis even for real structures with complex structural geometries. First, a new WUWI hardware system was developed by integrating optoelectronic-based signal transmitting and receiving devices and a scanning laser Doppler vibrometer. Next, a damage visualization algorithm, self-referencing f-k filter (SRF), was introduced to isolate and visualize only crack-induced ultrasonic modes from measured ultrasonic wavefield images. Finally, the performance of the proposed technique was validated through hidden crack visualization at a decommissioned Ramp-G Bridge in South Korea. The experimental results reveal that the proposed technique instantaneously detects and successfully visualizes hidden cracks even in the complex structure of a real bridge.

The Laser Level as an Optics Laboratory Tool

ERIC Educational Resources Information Center

Kutzner, Mickey

2013-01-01

For decades now, the laser has been used as a handy device for performing ray traces in geometrical optics demonstrations and laboratories. For many ray- trace applications, I have found the laser level 3 to be even more visually compelling and easy for student use than the laser pointer.

A Visualization Method for Corrosion Damage on Aluminum Plates Using an Nd:YAG Pulsed Laser Scanning System

PubMed Central

Lee, Inbok; Zhang, Aoqi; Lee, Changgil; Park, Seunghee

2016-01-01

This paper proposes a non-contact nondestructive evaluation (NDE) technique that uses laser-induced ultrasonic waves to visualize corrosion damage in aluminum alloy plate structures. The non-contact, pulsed-laser ultrasonic measurement system generates ultrasonic waves using a galvanometer-based Q-switched Nd:YAG laser and measures the ultrasonic waves using a piezoelectric (PZT) sensor. During scanning, a wavefield can be acquired by changing the excitation location of the laser point and measuring waves using the PZT sensor. The corrosion damage can be detected in the wavefield snapshots using the scattering characteristics of the waves that encounter corrosion. The structural damage is visualized by calculating the logarithmic values of the root mean square (RMS), with a weighting parameter to compensate for the attenuation caused by geometrical spreading and dispersion of the waves. An intact specimen is used to conduct a comparison with corrosion at different depths and sizes in other specimens. Both sides of the plate are scanned with the same scanning area to observe the effect of the location where corrosion has formed. The results show that the damage can be successfully visualized for almost all cases using the RMS-based functions, whether it formed on the front or back side. Also, the system is confirmed to have distinguished corroded areas at different depths. PMID:27999252

A Visualization Method for Corrosion Damage on Aluminum Plates Using an Nd:YAG Pulsed Laser Scanning System.

PubMed

Lee, Inbok; Zhang, Aoqi; Lee, Changgil; Park, Seunghee

2016-12-16

This paper proposes a non-contact nondestructive evaluation (NDE) technique that uses laser-induced ultrasonic waves to visualize corrosion damage in aluminum alloy plate structures. The non-contact, pulsed-laser ultrasonic measurement system generates ultrasonic waves using a galvanometer-based Q-switched Nd:YAG laser and measures the ultrasonic waves using a piezoelectric (PZT) sensor. During scanning, a wavefield can be acquired by changing the excitation location of the laser point and measuring waves using the PZT sensor. The corrosion damage can be detected in the wavefield snapshots using the scattering characteristics of the waves that encounter corrosion. The structural damage is visualized by calculating the logarithmic values of the root mean square (RMS), with a weighting parameter to compensate for the attenuation caused by geometrical spreading and dispersion of the waves. An intact specimen is used to conduct a comparison with corrosion at different depths and sizes in other specimens. Both sides of the plate are scanned with the same scanning area to observe the effect of the location where corrosion has formed. The results show that the damage can be successfully visualized for almost all cases using the RMS-based functions, whether it formed on the front or back side. Also, the system is confirmed to have distinguished corroded areas at different depths.

Laser Technology in Aerodynamic Measurements.

DTIC Science & Technology

holography; Laser beam probing for aerodynamic flow field analysis; The laser in high speed photography; Laser metrology; Application of duel scatter laser doppler velocimeters for wind tunnel measurements.

Numerical simulation of heat transfer and fluid flow during double-sided laser beam welding of T-joints for aluminum aircraft fuselage panels

NASA Astrophysics Data System (ADS)

Yang, Zhibin; Tao, Wang; Li, Liqun; Chen, Yanbin; Shi, Chunyuan

2017-06-01

In comparison with conventional laser beam welding, double-sided laser beam welding has two laser heat sources simultaneously and symmetrically loaded from both sides makes it to be a more complicated coupled heat transport and fluid flow process. In this work, in order to understand the heat transfer and fluid flow, a three-dimensional model was developed and validated with the experimental results. The temperature field, fluid flow field, and keyhole characteristic were calculated using the developed model by FLUENT software. Calculated results indicated that the temperature and fluid flow fields were bilateral symmetry along the stringer center, and the molten pool maximum length was located near the keyhole intersection position. The skin side had higher temperature and faster cooling speed. Several characteristic flow patterns in the weld pool cross section, including the vortexes flows near the keyhole opening position, the convection flows above the keyhole intersection location, the regularity downward flows at the molten pool bottom. And in the lengthwise section, a distinct vortex flow below the keyhole, and the liquid metal behind the keyhole first flowed to near the molten pool maximum length location and then to the molten pool surface. Perpendicular to and along welding direction the keyhole liquid metal flowed to the weld molten pool surface and around the keyhole, respectively. The special temperature fields and fluid flow patterns were closely related to the effects of the double sides' laser energy coupling and enhancement. The calculated weld pool geometry basically in good agreement with the experimental results indicated that the developed model was validity and reasonable.

Thermocapillary migration of liquid droplets in a temperature gradient in a density matched system

NASA Technical Reports Server (NTRS)

Rashidnia, N.; Balasubramaniam, R.

1991-01-01

An experimental investigation of thermocapillary flow in droplets of a vegetable oil (partially hydrogenated soybean oil) immersed in silicone oil was conducted in a test cell with a heated top wall and a cooled bottom wall. The liquids are nearly immiscible and have equal densities at a temperature below the room temperature, thus providing a simulation of low-gravity conditions by reducing the buoyancy forces. The interfacial tension between the two oils was measured in the temperature range 20 to 50 C using a capillary tube and (d sigma)/(d T) was determined to be negative. Droplets ranging in sizes from 3 mm to 1 cm diameter were injected into the silicone oil. The vertical temperature profile in the bulk liquid (silicone oil) produces temperature variations along the interface which induce variations in the interfacial tension. The flow inside the droplet driven by the resulting interfacial shear stresses was observed using a laser light-sheet flow visualization technique. The flow direction is consistent with the sign of (d sigma)/(d T). The observed maximum surface velocities are compared to the theoretical predictions of Young et al. (1959).

Thermocapillary migration of liquid droplets in a temperature gradient in a density matched system

NASA Technical Reports Server (NTRS)

Rashidnia, N.; Balasubramaniam, R.

1989-01-01

An experimental investigation of thermocapillary flow in droplets of a vegetable oil (partially hydrogenated soybean oil) immersed in silicone oil was conducted in a test cell with a heated top wall and a cooled bottom wall. The liquids are nearly immiscible and have equal densities at a temperature below the room temperature, thus providing a simulation of low-gravity conditions by reducing the buoyancy forces. The interfacial tension between the two oils was measured in the temperature range 20 to 50 C using a capillary tube and (d sigma)/(d T) was determined to be negative. Droplets ranging in sizes from 3 mm to 1 cm diameter were injected into the silicone oil. The vertical temperature profile in the bulk liquid (silicone oil) produces temperature variations along the interface which induce variations in the interfacial tension. The flow inside the droplet driven by the resulting interfacial shear stresses was observed using a laser light-sheet flow visualization technique. The flow direction is consistent with the sign of (d sigma)/(d T). The observed maximum surface velocities are compared to the theoretical predictions of Young et al. (1959).

Linking pain and the body: neural correlates of visually induced analgesia.

PubMed

Longo, Matthew R; Iannetti, Gian Domenico; Mancini, Flavia; Driver, Jon; Haggard, Patrick

2012-02-22

The visual context of seeing the body can reduce the experience of acute pain, producing a multisensory analgesia. Here we investigated the neural correlates of this "visually induced analgesia" using fMRI. We induced acute pain with an infrared laser while human participants looked either at their stimulated right hand or at another object. Behavioral results confirmed the expected analgesic effect of seeing the body, while fMRI results revealed an associated reduction of laser-induced activity in ipsilateral primary somatosensory cortex (SI) and contralateral operculoinsular cortex during the visual context of seeing the body. We further identified two known cortical networks activated by sensory stimulation: (1) a set of brain areas consistently activated by painful stimuli (the so-called "pain matrix"), and (2) an extensive set of posterior brain areas activated by the visual perception of the body ("visual body network"). Connectivity analyses via psychophysiological interactions revealed that the visual context of seeing the body increased effective connectivity (i.e., functional coupling) between posterior parietal nodes of the visual body network and the purported pain matrix. Increased connectivity with these posterior parietal nodes was seen for several pain-related regions, including somatosensory area SII, anterior and posterior insula, and anterior cingulate cortex. These findings suggest that visually induced analgesia does not involve an overall reduction of the cortical response elicited by laser stimulation, but is consequent to the interplay between the brain's pain network and a posterior network for body perception, resulting in modulation of the experience of pain.

Flow and performance of an air-curtain biological safety cabinet.

PubMed

Huang, Rong Fung; Chou, Chun I

2009-06-01

Using laser-assisted smoke flow visualization and tracer gas concentration detection techniques, this study examines aerodynamic flow properties and the characteristics of escape from containment, inward dispersion, and cross-cabinet contamination of a biological safety cabinet installed with an air curtain across the front aperture. The experimental method partially simulates the NSF/ANSI 49 standards with the difference that the biological tracer recommended by these standards is replaced by a mixture of 10% SF(6) in N(2). The air curtain is set up across the cabinet aperture plane by means of a narrow planar jet issued from the lower edge of the sash and a suction flow going through a suction slot installed at the front edge of the work surface. Varying the combination of jet velocity, suction flow velocity, and descending flow velocity reveals three types of characteristic flow modes: 'straight curtain', 'slightly concave curtain', and 'severely concave curtain'. Operating the cabinet in the straight curtain mode causes the air curtain to impinge on the doorsill and therefore induces serious escape from containment. In the severely concave curtain mode, drastically large inward dispersion and cross-cabinet contamination were observed because environmental air entered into the cabinet and a three-dimensional vortical flow structure formed in the cabinet. The slightly concave curtain mode presents a smooth and two-dimensional flow pattern with an air curtain separating the outside atmosphere from the inside space of the cabinet, and therefore exhibited negligibly small escape from containment, inward dispersion, and cross-cabinet contamination.

A laboratory study of mean flow generation in rotating fluids by Reynolds stress gradients

NASA Astrophysics Data System (ADS)

McGuinness, D. S.; Boyer, D. L.; Fernando, H. J. S.

2001-06-01

Laboratory experiments were conducted that demonstrate that a mean azimuthal flow can be produced by introducing Reynolds stress gradients to a rotating fluid with zero initial mean flow. This mechanism may play a role in the generation of mean currents in coastal regions. The experiments entail the establishment of turbulence in a thin annular-shaped region centered within a cylindrical test cell through the use of a vertically oscillating grid. This region rests in a horizontal plane perpendicular to the vertical axis of the tank, and the entire system is placed on a turntable to simulate background rotation. Flow visualization techniques are used to depict qualitative features of the resulting flow field. Measurements of the mean and turbulent velocity fields are performed using a two-component laser-Doppler velocimeter. The results show how rectified currents (mean flows) can be generated via Reynolds stress gradients induced by periodic forcing of the grid. In the absence of background rotation, rectified flow is observed in the radial and vertical directions only. The presence of background rotation tends to organize these motions in that the flow tends to move parallel to the turbulent source, i.e., in the azimuthal direction, with the source (strong turbulence) located to the right, facing downstream. The influence of rotation on the Reynolds stresses and their gradients as well as on the ensuing mean flow is evaluated, and the observations are examined by considering individual contributions of the terms in the Reynolds-averaged momentum equations.

Three-dimensional vortex patterns in a starting flow

NASA Astrophysics Data System (ADS)

Freymuth, P.; Finaish, F.; Bank, W.

1985-12-01

Freymuth et al. (1983, 1984, 1985) have conducted investigations involving chordwise vortical-pattern visualizations in a starting flow of constant acceleration around an airfoil. Detailed resolution of vortical shapes in two dimensions could be obtained. No visualization in the third spanwise dimension is needed as long as the flow remains two-dimensional. However, some time after flow startup, chordwise vortical patterns become blurred, indicating the onset of turbulence. The present investigation is concerned with an extension of the flow visualization from a chordwise cross section to the spanwise dimension. The investigation has the objective to look into the two-dimensionality of the initial vortical developments and to resolve three-dimensional effects during the transition to turbulence. Attention is given to the visualization method, the chordwise vs spanwise visualization in the two-dimensional regime, the spanwise visualization of transition, and the visualization of vortical patterns behind the trailing edge.

Utility and safety of a novel surgical microscope laser light source

PubMed Central

Bakhit, Mudathir S.; Suzuki, Kyouichi; Sakuma, Jun; Fujii, Masazumi; Murakami, Yuta; Ito, Yuhei; Sugano, Tetsuo; Saito, Kiyoshi

2018-01-01

Objective Tissue injuries caused by the thermal effects of xenon light microscopes have previously been reported. Due to this, the development of a safe microscope light source became a necessity. A newly developed laser light source is evaluated regarding its effectiveness and safety as an alternative to conventional xenon light source. Methods We developed and tested a new laser light source for surgical microscopes. Four experiments were conducted to compare xenon and laser lights: 1) visual luminance comparison, 2) luminous and light chromaticity measurements, 3) examination and analysis of visual fatigue, and 4) comparison of focal temperature elevation due to light source illumination using porcine muscle samples. Results Results revealed that the laser light could be used at a lower illumination value than the xenon light (p < 0.01). There was no significant difference in visual fatigue status between the laser light and the xenon light. The laser light was superior to the xenon light regarding luminous intensity and color chromaticity. The focal temperature elevation of the muscle samples was significantly higher when irradiated with xenon light in vitro than with laser light (p < 0.01). Conclusion The newly developed laser light source is more efficient and safer than a conventional xenon light source. It lacks harmful ultraviolet waves, has a longer lifespan, a lower focal temperature than that of other light sources, a wide range of brightness and color production, and improved safety for the user’s vision. Further clinical trials are necessary to validate the impact of this new light source on the patient’s outcome and prognosis. PMID:29390016

REVIEWS OF TOPICAL PROBLEMS: Gas lasers with solar excitation

NASA Astrophysics Data System (ADS)

Gordiets, B. F.; Panchenko, Vladislav Ya

1986-07-01

CONTENTS 1. Introduction 703 2. General requirements for laser media using solar excitation 704 3. Lasers with direct excitation by solar light 705 3.1. Basic characteristics of laser media. 3.2. Photodissociation Br2-CO2 lasers. 3.3. Interhalogen molecule lasers. 3.4. Iodine lasers. 3.5. Alkali metal vapor lasers. 4. Lasers with thermal conversion of solar pumping 709 4.1. General considerations. 4.2. CO2 laser with excitation in a black body cavity and with gas flow. 4.3. cw CO2 laser without gas flow. 5. Space laser media with solar excitation 713 5.1. Population inversion of molecular levels in the outer atmosphere of the Earth. 5.2. Laser effect in the atmospheres of Venus and Mars. 5.3. Terrestrial experimental technique for observing infrared emission in the atmospheres of planets. 5.4. Designs for laser systems in the atmospheres of Venus and Mars. 6. Conclusions 717 References 717

Four-Spot Time-Of-Flight Laser Anemometer For Turbomachinery

NASA Technical Reports Server (NTRS)

Wernet, Mark P.; Skoch, Gary J.

1995-01-01

Two-color, four-spot time-of-flight laser anemometer designed for measuring flow velocity within narrow confines of small centrifugal compressor. Apparatus well suited for measuring fast (typical speeds 160 to 700 m/s), highly turbulent gas flows in turbomachinery. Other potential applications include measurement of gas flows in pipelines and in flows from explosions.

An ultra-high-speed cinematographic method for the study of wakes in hypersonic ballistic ranges

NASA Astrophysics Data System (ADS)

Koeneke, Axel; Jaeggy, Bernard Charles; Koerber, Germain

1987-11-01

Optical methods are among the only possibilities to study hypersonic wakes in ballistic ranges. Because of the flow velocities involved the methods employed must permit exposure time well below one microsecond. The ISL has used ultrahigh speed visualization techniques for the study of the transition of hypersonic wakes for quite some time, but the means available up to now did not permit investigation of the time-history of the instabilities in the wake. The use of a laser equipped with an acousto-optical modulator is proposed as a source of ultrashort, highly energetic pulses with high repetition rate to be used to record a certain number of images of the same experiment in order to study the time history of these instabilities. Advantages of the laser as a light source are not only the high energies available together with pulse duration down to 20 nanoseconds, but mostly the free choice of repetition rate independently of exposure time, and the possibility to synchronize the pulses with external events. The laser is a point source and as such can be used in a variety of different optical setups. The coherent nature of the laser light even permits holographic techniques. The reception system capable of recording the images at a sufficient rate is the basic problem in the development and use of the proposed setup.

Enhancing the reproducibility of ocular vestibular evoked myogenic potentials by use of a visual target originating from a head-mounted laser.

PubMed

Jerin, Claudia; Bartl, Klaus; Schneider, Erich; Gürkov, Robert

2015-10-01

Ocular vestibular evoked myogenic potentials (oVEMPs) represent extraocular muscle activity in response to vestibular stimulation. oVEMP amplitudes are known to increase with increasing upward gaze angle, while the patient fixates a visual target. We investigated two different methods of presenting a visual target during oVEMP recordings. 57 healthy subjects were enrolled in this study. oVEMPs were elicited by 500 Hz air-conducted tone bursts while the subjects were looking upward at a marking which was either fixed on the wall or originated from a head-mounted laser attached to a headband, in either case corresponding to a 35° upward gaze angle. oVEMP amplitudes and latencies did not differ between the subjects looking at the fixed marking and the ones looking at the laser marking. The intra-individual standard deviation of amplitudes obtained by two separate measurements for each subject, however, as a measure of test-retest reliability, was significantly smaller for the laser headband group (0.60) in comparison to the group looking at the fixed marking (0.96; p = 0.007). The intraclass correlation coefficient revealed better test-retest reliability for oVEMP amplitudes when using the laser headband (0.957) than using the fixed marking (0.908). Hence, the use of a visual target originating from a headband enhances the reproducibility of oVEMPs. This might be due to the fact that the laser headband ensures a constant gaze angle and rules out the influence of small involuntary head movements on the gaze angle.

Visual outcome and refractive status in first 3 years of age in preterm infants suffered from laser-treated Type 1 retinopathy of prematurity (ROP): a 6-year retrospective review in a tertiary centre in Hong Kong.

PubMed

Lok, Julie Y C; Yip, Wilson W K; Luk, Abbie S W; Chin, Joyce K Y; Lau, Henry H W; Young, Alvin L

2018-02-01

To report the visual outcome and refractive status in first 3 years of age in preterm infants suffered from laser-treated Type 1 retinopathy of prematurity (ROP): a 6-year review in Hong Kong DESIGN: Retrospective case series METHODOLOGY: Clinical records of all infants suffered from Type 1 ROP who had undergone laser therapy between 2007 and 2012 were retrospectively reviewed. Basic demographic data, serial changes of refractive error, visual acuity, severity of ROP and laser were analyzed. Correlation with myopia and astigmatism progression, body weight, height, growth and gestational age were also analyzed. Among 494 babies screened, 14 Chinese babies (26 eyes) recruited with 1:1 male-to-female ratio in this study. All eyes showed gradual progression of myopia in first 3 years of age but no significant change of astigmatism. Further correlation analysis showed no correlation with laser energy consumed, birth weight (p = 0.14), head circumference growth (p = 0.57) and body weight growth (p = 0.71). However, severity of myopia was related to the post-conceptual age when receiving laser therapy (p < 0.005), gestation age (p = 0.02) and possibly body height growth with age (p = 0.05). Myopia in early life is one of the most common ocular sequelae in Type 1 ROP survivors. Early detection of refractive error is important for prompt correction and visual rehabilitation to prevent amblyopia.

Wind Tunnel Application of a Pressure-Sensitive Paint Technique to a Faceted Missile Model at Subsonic and Transonic Speeds

NASA Technical Reports Server (NTRS)

Erickson, Gary E.

2004-01-01

A pressure-sensitive paint (PSP) technique was applied in a wind tunnel experiment in the NASA Langley Research Center 8-Foot Transonic Pressure Tunnel to quantify the vortex-induced surface static pressures on a slender, faceted missile model at subsonic and transonic speeds. Global PSP calibrations were obtained using an in-situ method featuring the simultaneous electronically-scanned pressures (ESP) measurements. Both techniques revealed the significant influence leading-edge vortices on the surface pressure distributions. The mean error in the PSP measurements relative to the ESP data was approximately 0.6 percent at M(sub infinity)=0.70 and 2.6 percent at M(sub infinity)=0.90 and 1.20. The vortex surface pressure signatures obtained from the PSP and ESP techniques were correlated with the off-surface vortex cross-flow structures obtained using a laser vapor screen (LVS) flow visualization technique. The on-surface and off-surface techniques were complementary, since each provided details of the vortex-dominated flow that were not clear or apparent in the other.

Low turbulence/high efficiency cyclone separators: Facility qualification results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Razgaitis, R.; Paul, D.D.; Bioarski, A.A.

1985-01-01

The objective of this work is to experimentally investigate the near-wall turbulent flow-fields characteristic of cyclone separators in order to determine the influence of wall-originating turbulence on the separation of fine particles. In particular, seven turbulence suppression concepts will be evaluated with reference to a well-established baseline condition. Concepts which appear attractive will be studied and characterized in more detail. The work accomplished to date is principally the design, construction, and qualification of two of the facilities that will be used to study the various concepts of turbulence suppression. The qualification of the primary facility, the Cyclonic Wind Tunnel (CWT),more » has required the development and adaptation of laser Doppler velocimetry (LDV) to perform simultaneous two-dimensional turbulence measurements in a highly swirling flow. A companion facility to the CWT is the Curvilinear Boundary Layer (CBL) apparatus. The purpose of the CBL is to provide a thick, visually-observable near-wall flow region under dynamically similar conditions to the CWT to that a physical understanding of the turbulence suppression process can be obtained. 9 refs., 15 figs.« less

Ocular blood flow parameters after pars plana vitrectomy in patients with diabetic retinopathy.

PubMed

Krepler, Katharina; Polska, Elzbieta; Wedrich, Andreas; Schmetterer, Leopold

2003-04-01

Whereas the anatomic result of vitrectomy in patients with vitreoretinal complications due to diabetes is usually satisfying, the functional outcome is sometimes poor. The authors investigated whether this may be related in part to effects of vitrectomy on ocular perfusion. Ocular hemodynamics were measured before vitrectomy and 1 and 4 weeks postoperatively in 13 consecutive diabetic patients. Pulsatile choroidal blood flow was assessed with laser interferometric measurement of fundus pulsation amplitude. In addition, mean blood flow velocity and resistive index in the ophthalmic artery, the central retinal artery, and the posterior ciliary arteries were measured with color Doppler imaging. Fundus pulsation amplitude was significantly reduced after surgery as compared to baseline (baseline: 3.7 +/- 1.0 microm; 4 weeks: 3.1 +/- 0.8; P < 0.001). Postoperatively, mean blood flow velocity in the central retinal artery (P = 0.009) and the posterior ciliary arteries (P = 0.0006) was significantly reduced, whereas resistive index was increased in the central retinal artery (P = 0.028) but not in the posterior ciliary arteries. The current data suggest that vitrectomy induces significant reductions in ocular blood flow in patients with diabetic retinopathy. Whether this may affect the visual outcome after vitrectomy or whether this reflects improved retinal oxygenation after vitrectomy remains to be established.

Improvement of Hungarian Joint Terminal Attack Program

DTIC Science & Technology

2013-06-13

LST Laser Spot Tracker NVG Night Vision Goggle ROMAD Radio Operator Maintainer and Driver ROVER Remotely Operated Video Enhanced Receiver TACP...visual target designation. The other component consists of a laser spot tracker (LST), which identifies targets by tracking laser energy reflecting...capability for every type of night time missions, laser spot tracker for laser spot search missions, remotely operated video enhanced receiver

Performance comparison of supersonic ejectors with different motive gas injection schemes applicable for flowing medium gas laser

NASA Astrophysics Data System (ADS)

Singhal, G.; Subbarao, P. M. V.; Mainuddin; Tyagi, R. K.; Dawar, A. L.

2017-05-01

A class of flowing medium gas lasers with low generator pressures employ supersonic flows with low cavity pressure and are primarily categorized as high throughput systems capable of being scaled up to MW class. These include; Chemical Oxygen Iodine Laser (COIL) and Hydrogen (Deuterium) Fluoride (HF/DF). The practicability of such laser systems for various applications is enhanced by exhausting the effluents directly to ambient atmosphere. Consequently, ejector based pressure recovery forms a potent configuration for open cycle operation. Conventionally these gas laser systems require at least two ejector stages with low pressure stage being more critical, since it directly entrains the laser media, and the ensuing perturbation of cavity flow, if any, may affect laser operation. Hence, the choice of plausible motive gas injection schemes viz., peripheral or central is a fluid dynamic issue of interest, and a parametric experimental performance comparison would be beneficial. Thus, the focus is to experimentally characterize the effect of variation in motive gas supply pressure, entrainment ratio, back pressure conditions, nozzle injection position operated together with a COIL device and discern the reasons for the behavior.

Oil-Water Flow Investigations using Planar-Laser Induced Fluorescence and Particle Velocimetry

NASA Astrophysics Data System (ADS)

Ibarra, Roberto; Matar, Omar K.; Markides, Christos N.

2017-11-01

The study of the complex behaviour of immiscible liquid-liquid flow in pipes requires the implementation of advanced measurement techniques in order to extract detailed in situ information. Laser-based diagnostic techniques allow the extraction of high-resolution space- and time resolve phase and velocity information, which aims to improve the fundamental understanding of these flows and to validate closure relations for advanced multiphase flow models. This work shows a novel simultaneous planar-laser induced fluorescence and particle velocimetry in stratified oil-water flows using two laser light sheets at two different wavelengths for fluids with different refractive indices at horizontal and upward pipe inclinations (<5°) in stratified flow conditions (i.e. separated layers). Complex flow structures are extracted from 2-D instantaneous velocity fields, which are strongly dependent on the pipe inclination at low velocities. The analysis of mean wall-normal velocity profiles and velocity fluctuations suggests the presence of single- and counter-rotating vortices in the azimuthal direction, especially in the oil layer, which can be attributed to the influence of the interfacial waves. Funding from BP, and the TMF Consortium is gratefully acknowledged.

Theoretical analysis for scaling law of thermal blooming based on optical phase deference

NASA Astrophysics Data System (ADS)

Sun, Yunqiang; Huang, Zhilong; Ren, Zebin; Chen, Zhiqiang; Guo, Longde; Xi, Fengjie

2016-10-01

In order to explore the laser propagation influence of thermal blooming effect of pipe flow and to analysis the influencing factors, scaling law theoretical analysis of the thermal blooming effects in pipe flow are carry out in detail based on the optical path difference caused by thermal blooming effects in pipe flow. Firstly, by solving the energy coupling equation of laser beam propagation, the temperature of the flow is obtained, and then the optical path difference caused by the thermal blooming is deduced. Through the analysis of the influence of pipe size, flow field and laser parameters on the optical path difference, energy scaling parameters Ne=nTαLPR2/(ρɛCpπR02) and geometric scaling parameters Nc=νR2/(ɛL) of thermal blooming for the pipe flow are derived. Secondly, for the direct solution method, the energy coupled equations have analytic solutions only for the straight tube with Gauss beam. Considering the limitation of directly solving the coupled equations, the dimensionless analysis method is adopted, the analysis is also based on the change of optical path difference, same scaling parameters for the pipe flow thermal blooming are derived, which makes energy scaling parameters Ne and geometric scaling parameters Nc have good universality. The research results indicate that when the laser power and the laser beam diameter are changed, thermal blooming effects of the pipeline axial flow caused by optical path difference will not change, as long as you keep energy scaling parameters constant. When diameter or length of the pipe changes, just keep the geometric scaling parameters constant, the pipeline axial flow gas thermal blooming effects caused by optical path difference distribution will not change. That is to say, when the pipe size and laser parameters change, if keeping two scaling parameters with constant, the pipeline axial flow thermal blooming effects caused by the optical path difference will not change. Therefore, the energy scaling parameters and the geometric scaling parameters can really describe the gas thermal blooming effect in the axial pipe flow. These conclusions can give a good reference for the construction of the thermal blooming test system of laser system. Contrasted with the thermal blooming scaling parameters of the Bradley-Hermann distortion number ND and Fresnel number NF, which were derived based on the change of far field beam intensity distortion, the scaling parameters of pipe flow thermal blooming deduced from the optical path deference variation are very suitable for the optical system with short laser propagation distance, large Fresnel number and obviously changed optical path deference.

Selective IR multiphoton dissociation of molecules in a pulsed gas-dynamically cooled molecular flow interacting with a solid surface as an alternative to low-energy methods of molecular laser isotope separation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Makarov, G N; Petin, A N

2016-03-31

We report the results of studies on the isotope-selective infrared multiphoton dissociation (IR MFD) of SF{sub 6} and CF{sub 3}I molecules in a pulsed, gas-dynamically cooled molecular flow interacting with a solid surface. The productivity of this method in the conditions of a specific experiment (by the example of SF{sub 6} molecules) is evaluated. A number of low-energy methods of molecular laser isotope separation based on the use of infrared lasers for selective excitation of molecules are analysed and their productivity is estimated. The methods are compared with those of selective dissociation of molecules in the flow interacting with amore » surface. The advantages of this method compared to the low-energy methods of molecular laser isotope separation and the IR MPD method in the unperturbed jets and flows are shown. It is concluded that this method could be a promising alternative to the low-energy methods of molecular laser isotope separation. (laser separation of isotopes)« less

The effect of CNC and manual laser machining on electrical resistance of HDPE/MWCNT composite

NASA Astrophysics Data System (ADS)

Mohammadi, Fatemeh; Farshbaf Zinati, Reza; Fattahi, A. M.

2018-05-01

In this study, electrical conductivity of high-density polyethylene (HDPE)/multi-walled carbon nanotube (MWCNT) composite was investigated after laser machining. To this end, produced using plastic injection process, nano-composite samples were laser machined with various combinations of input parameters such as feed rate (35, 45, and 55 mm/min), feed angle with injection flow direction (0°, 45°, and 90°), and MWCNT content (0.5, 1, and 1.5 wt%). The angle between laser feed and injected flow direction was set via either of two different methods: CNC programming and manual setting. The results showed that the parameters of angle between laser line and melt flow direction and feed rate were both found to have statistically significance and physical impacts on electrical resistance of the samples in manual setting. Also, maximum conductivity was seen when the angle between laser line and melt flow direction was set to 90° in manual setting, and maximum conductivity was seen at feed rate of 55 mm/min in both of CNC programming and manual setting.

Indoor space 3D visual reconstruction using mobile cart with laser scanner and cameras

NASA Astrophysics Data System (ADS)

Gashongore, Prince Dukundane; Kawasue, Kikuhito; Yoshida, Kumiko; Aoki, Ryota

2017-02-01

Indoor space 3D visual reconstruction has many applications and, once done accurately, it enables people to conduct different indoor activities in an efficient manner. For example, an effective and efficient emergency rescue response can be accomplished in a fire disaster situation by using 3D visual information of a destroyed building. Therefore, an accurate Indoor Space 3D visual reconstruction system which can be operated in any given environment without GPS has been developed using a Human-Operated mobile cart equipped with a laser scanner, CCD camera, omnidirectional camera and a computer. By using the system, accurate indoor 3D Visual Data is reconstructed automatically. The obtained 3D data can be used for rescue operations, guiding blind or partially sighted persons and so forth.

An Investigation of Laser Lighting Systems to Assist Aircraft

DOT National Transportation Integrated Search

1979-01-01

A model for the visual detectability of narrow light beams was developed and used to evaluate the system performance of two laser lighting system configurations: (1) a laser VASI and (2) a crossed beam glide path indicator. Laboratory experiments con...

Swirl, Expansion Ratio and Blockage Effects on Confined Turbulent Flow. M.S. Thesis

NASA Technical Reports Server (NTRS)

Scharrer, G. L.

1982-01-01

A confined jet test facility, a swirles, flow visualization equipment, five-hole pitot probe instrumentation; flow visualization; and effects of swirl on open-ended flows, of gradual expansion on open-ended flows, and blockages of flows are addressed.

Thermal Nonequilibrium in Hypersonic Separated Flow

DTIC Science & Technology

2014-12-22

flow duration and steadiness. 15. SUBJECT TERMS Hypersonic Flowfield Measurements, Laser Diagnostics of Gas Flow, Laser Induced...extent than the NS computation. While it would be convenient to believe that the more physically realistic flow modeling of the DSMC gas - surface...index and absorption coefficient. Each of the curves was produced assuming a 0.5 % concentration of lithium at the Condition A nozzle exit conditions

Underwater Flow Visualization Methods in the Upper Layer of the Ocean.

DTIC Science & Technology

1981-05-22

AD-A107 919 NAVAL RESEARCH LAB WASHINGTON DC F/G 8/3 UNDERWATER FLOW VISUALIZATION METHODS IN T1E UPPER LAYER OF THE-ETC(U) AMAY 81 J R MCGRATH, C M...S.bOti1.) S. TYPE OF REPORT I PERIOD COVERED UNDERWATER FLOW VISUALIZATION METHODS Interim report on a continuingNRL problem. IN THE UPPER LAYER OF THE...56 UNDERWATER FLOW VISUALIZATION METHODS IN THE UPPER LAYER OF THE OCEAN 1. INTRODUCTION a) Purpose This report documents the

In-flight flow visualization with pressure measurements at low speeds on the NASA F-18 high alpha research vehicle

NASA Technical Reports Server (NTRS)

Delfrate, John H.; Fisher, David F.; Zuniga, Fanny A.

1990-01-01

In-flight results from surface and off-surface flow visualizations and from extensive pressure distributions document the vortical flow on the leading edge extensions (LEX) and forebody of the NASA F-18 high alpha research vehicle for low speeds and angles of attack up to 50 degs. Surface flow visualization data, obtained using the emitted fluid technique, were used to define separation lines and laminar separation bubbles. Off-surface flow visualization data, obtained by smoke injection, were used to document both the path of the vortex cores and the location of vortex core breakdown. The location of vortex core breakdown correlated well with the loss of suction pressure on the LEX and with the flow visualization results from ground facilities. Surface flow separation lines on the LEX and forebody corresponded well with the end of pressure recovery under the vortical flows. Correlation of the pressures with wind tunnel results show fair to good correlation.

Shaded computer graphic techniques for visualizing and interpreting analytic fluid flow models

NASA Technical Reports Server (NTRS)

Parke, F. I.

1981-01-01

Mathematical models which predict the behavior of fluid flow in different experiments are simulated using digital computers. The simulations predict values of parameters of the fluid flow (pressure, temperature and velocity vector) at many points in the fluid. Visualization of the spatial variation in the value of these parameters is important to comprehend and check the data generated, to identify the regions of interest in the flow, and for effectively communicating information about the flow to others. The state of the art imaging techniques developed in the field of three dimensional shaded computer graphics is applied to visualization of fluid flow. Use of an imaging technique known as 'SCAN' for visualizing fluid flow, is studied and the results are presented.

Patient-specific in vitro models for hemodynamic analysis of congenital heart disease - Additive manufacturing approach.

PubMed

Medero, Rafael; García-Rodríguez, Sylvana; François, Christopher J; Roldán-Alzate, Alejandro

2017-03-21

Non-invasive hemodynamic assessment of total cavopulmonary connection (TCPC) is challenging due to the complex anatomy. Additive manufacturing (AM) is a suitable alternative for creating patient-specific in vitro models for flow measurements using four-dimensional (4D) Flow MRI. These in vitro systems have the potential to serve as validation for computational fluid dynamics (CFD), simulating different physiological conditions. This study investigated three different AM technologies, stereolithography (SLA), selective laser sintering (SLS) and fused deposition modeling (FDM), to determine differences in hemodynamics when measuring flow using 4D Flow MRI. The models were created using patient-specific MRI data from an extracardiac TCPC. These models were connected to a perfusion pump circulating water at three different flow rates. Data was processed for visualization and quantification of velocity, flow distribution, vorticity and kinetic energy. These results were compared between each model. In addition, the flow distribution obtained in vitro was compared to in vivo. The results showed significant difference in velocities measured at the outlets of the models that required internal support material when printing. Furthermore, an ultrasound flow sensor was used to validate flow measurements at the inlets and outlets of the in vitro models. These results were highly correlated to those measured with 4D Flow MRI. This study showed that commercially available AM technologies can be used to create patient-specific vascular models for in vitro hemodynamic studies at reasonable costs. However, technologies that do not require internal supports during manufacturing allow smoother internal surfaces, which makes them better suited for flow analyses. Copyright © 2017 Elsevier Ltd. All rights reserved.

Fabrication, measurement, and modeling of electro-osmotic flow in micromachined polymer microchannels

NASA Astrophysics Data System (ADS)

Suriyage, Nihal U.; Ghantasala, Muralidhar K.; Iovenitti, Pio; Harvey, Erol C.

2004-03-01

Electroosmotic pumping in the microchannels fabricated in polycarbonate (PC), polyethyleneterephthalate (PET) and SU-8 polymer substrates was investigated and species transportation was modeled, in an attempt to show the suitability of low cost polymer materials for the development of disposable microfluidic devices. Microchannels and the fluid reservoirs were fabricated using excimer laser ablation and hot embossing techniques. Typical dimensions of the microchannels were 60μm (width) x 50μm (depth) x 45mm (length). Species transportation in the microchannels under electroosmosis was modeled by finite element method (FEM) with the help of NetFlow module of the CoventorWareTM computational fluid dynamics (CFD) package. In particular, electroosmosis and electrophoresis in a crossed microfluidic channel was modeled to calculate the percentage species mass transportation when the concentration shape of the Gaussian input species plug and the location of the injection point are varied. Change in the concentration shape of the initial species plug while it is electroosmotically transported along the crossed fluidic channel was visualized. Results indicated that Excimer laser ablated PC and PET devices have electroosmotic mobility in the range 2 to 5 x10-4 cm2/V.s, zeta potential 30 to 70 mV and flow rates of the order of 1 to 3 nL/s under an electric field of 200 V/cm. With the electroosmotic mobility value of PC the simulation results show that a crossed fluidic channel is electroosmotically pumping about 91% of the species mass injected along one of its straight channels.

A laser interferometer for measuring skin friction in three-dimensional flows

NASA Technical Reports Server (NTRS)

Monson, D. J.

1983-01-01

A new, nonintrusive method is described for measuring skin friction in three-dimensional flows with unknown direction. The method uses a laser interferometer to measure the changing slope of a thin oil film applied to a surface experiencing shear stress. The details of the method are described, and skin friction measurements taken in a swirling three-dimensional boundary-layer flow are presented. Comparisons between analytical results and experimental values from the laser interferometer method and from a bidirectional surface-fence gauge are made.

Intravitreal Aflibercept Injection in Eyes With Substantial Vision Loss After Laser Photocoagulation for Diabetic Macular Edema: Subanalysis of the VISTA and VIVID Randomized Clinical Trials.

PubMed

Wykoff, Charles C; Marcus, Dennis M; Midena, Edoardo; Korobelnik, Jean-François; Saroj, Namrata; Gibson, Andrea; Vitti, Robert; Berliner, Alyson J; Williams Liu, Zinaria; Zeitz, Oliver; Metzig, Carola; Schmelter, Thomas; Heier, Jeffrey S

2016-12-22

Information on the effect of anti-vascular endothelial growth factor therapy in eyes with diabetic macular edema (DME) with vision loss after macular laser photocoagulation is clinically valuable. To evaluate visual and anatomic outcomes in a subgroup of macular laser photocoagulation treatment control (hereafter laser control) eyes with substantial vision loss receiving treatment with intravitreal aflibercept injection. This investigation was a post hoc analysis of a subgroup of laser control eyes in 2 phase 3 trials-VISTA (Study of Intravitreal Aflibercept Injection in Patients With Diabetic Macular Edema) and VIVID (Intravitreal Aflibercept Injection in Vision Impairment Due to DME)-in a multicenter setting. One hundred nine laser control eyes with center-involving DME were included. Treatment with intravitreal aflibercept injection (2 mg) every 8 weeks after 5 monthly doses with sham injections on nontreatment visits starting at week 24 was initiated on meeting prespecified criteria of at least a 10-letter visual acuity loss at 2 consecutive visits or at least a 15-letter visual acuity loss from the best previous measurement at 1 visit and vision not better than at baseline. Visual and anatomic outcomes in a subgroup of laser control eyes receiving treatment with intravitreal aflibercept injection. Through week 100, a total of 63 of 154 eyes (40.9%) in VISTA and 46 of 133 eyes (34.6%) in VIVID initially randomized to laser control received treatment with intravitreal aflibercept injection. The median time from week 24 to the first intravitreal aflibercept injection treatment was 34.0 (VISTA) and 83.5 (VIVID) days. In this subgroup, the mean (SD) visual gain from baseline to week 100 was 2.2 (12.5) (VISTA) and 3.8 (10.1) (VIVID) letters. At the time of intravitreal aflibercept injection initiation, these eyes had a mean (SD) loss of 11.0 (10.1) (VISTA) and 10.0 (6.5) (VIVID) letters from baseline, and they subsequently gained a mean (SD) of 17.4 (9.7) (VISTA) and 13.6 (8.6) (VIVID) letters from the initiation of treatment with intravitreal aflibercept injection through week 100. There was a minimal mean change in central subfield thickness from baseline in these eyes at the time of intravitreal aflibercept injection initiation (an increase of 3.9 μm in VISTA and a decrease of 3.0 μm in VIVID), after which further mean (SD) reductions of 285.6 (202.6) μm (VISTA) and 313.4 (181.9) μm (VIVID) occurred through week 100. Intravitreal aflibercept injection improves visual and anatomic outcomes in eyes experiencing substantial vision loss after macular laser photocoagulation treatment for DME. clinicaltrials.gov Identifiers: NCT01363440 and NCT01331681.

Lidar Investigation of Infiltration Water Heterogeneity in the Tamala Limestone, SW WA

NASA Astrophysics Data System (ADS)

Mahmud, K.; Mariethoz, G.; Treble, P. C.; Baker, A.

2014-12-01

To better manage groundwater resources in carbonate areas and improve our understanding of speleothem archives, it is important to understand and predict unsaturated zone hydrology in karst. The high level of complexity and spatial heterogeneity of such systems is challenging and requires knowledge of the typical geometry of karstic features. We present an exhaustive characterization of Golgotha Cave, SW Western Australia, based on an extensive LIDAR measurement campaign. The cave is developed in Quaternary age aeolianite (dune limestone) and contains speleothem records. We collect 30 representative 3D scan images from this site using FARO Focus3D, a high-speed 3D laser scanner, to visualize, study and extract 2D and 3D information from various points of view and at different scales. In addition to LIDAR data, 32 automatic drip loggers are installed at this site to measure the distribution and volume of water flow. We perform mathematical morphological analyses on the cave ceiling, to determine statistical information regarding the stalactites widths, lengths and spatial distribution. We determine a relationship between stalactites diameter and length. We perform tests for randomness to investigate the relationship between stalactite distribution and ceiling features such as fractures and apply this to identify different types of possible flow patterns such as fracture flow, solution pipe flow, primary matrix flow etc. We also relate stalactites density variation with topography of the cave ceiling which shows hydraulic gradient deviations. Finally we use Image Quilting, one of the recently developed multiple-point geostatistics methods, with the training images derived from LIDAR data to create a larger cave system to represent not only the caves that are visible, but the entire system which is inaccessible. As a result, an integral geological model is generated which may allow other scientists, geologist, to work on two different levels, integrating different speleothem datasets: (1) a basic level based on the accurate and metric support provided by the laser scanner; and (2) an advanced level using the image-based modelling.

Visual flow scene effects on the somatogravic illusion in non-pilots.

PubMed

Eriksson, Lars; von Hofsten, Claes; Tribukait, Arne; Eiken, Ola; Andersson, Peter; Hedström, Johan

2008-09-01

The somatogravic illusion (SGI) is easily broken when the pilot looks out the aircraft window during daylight flight, but it has proven difficult to break or even reduce the SGI in non-pilots in simulators using synthetic visual scenes. Could visual-flow scenes that accommodate compensatory head movement reduce the SGI in naive subjects? We investigated the effects of visual cues on the SGI induced by a human centrifuge. The subject was equipped with a head-tracked, head-mounted display (HMD) and was seated in a fixed gondola facing the center of rotation. The angular velocity of the centrifuge increased from near zero until a 0.57-G centripetal acceleration was attained, resulting in a tilt of the gravitoinertial force vector, corresponding to a pitch-up of 30 degrees. The subject indicated perceived horizontal continuously by means of a manual adjustable-plate system. We performed two experiments with within-subjects designs. In Experiment 1, the subjects (N = 13) viewed a darkened HMD and a presentation of simple visual flow beneath a horizon. In Experiment 2, the subjects (N = 12) viewed a darkened HMD, a scene including symbology superimposed on simple visual flow and horizon, and this scene without visual flow (static). In Experiment 1, visual flow reduced the SGI from 12.4 +/- 1.4 degrees (mean +/- SE) to 8.7 +/- 1.5 degrees. In Experiment 2, the SGI was smaller in the visual flow condition (9.3 +/- 1.8 degrees) than with the static scene (13.3 +/- 1.7 degrees) and without HMD presentation (14.5 +/- 2.3 degrees), respectively. It is possible to reduce the SGI in non-pilots by means of a synthetic horizon and simple visual flow conveyed by a head-tracked HMD. This may reflect the power of a more intuitive display for reducing the SGI.

Flow visualization V; Proceedings of the 5th International Symposium, Prague, Czechoslovakia, Aug. 21-25, 1989

NASA Astrophysics Data System (ADS)

Reznicek, R.

The present conference on flow visualization encompasses methods exploiting tracing particles, surface tracing methods, methods exploiting the effects of streaming fluid on passing radiation/field, computer-aided flow visualization, and applications to fluid mechanics, aerodynamics, flow devices, shock tubes, and heat/mass transfer. Specific issues include visualizing velocity distribution by stereo photography, dark-field Fourier quasiinterferometry, speckle tomography of an open flame, a fast eye for real-time image analysis, and velocity-field determination based on flow-image analysis. Also addressed are flows around rectangular prisms with oscillating flaps at the leading edges, the tomography of aerodynamic objects, the vapor-screen technique applied to a delta-wing aircraft, flash-lamp planar imaging, IR-thermography applications in convective heat transfer, and the visualization of marangoni effects in evaporating sessile drops.

Measurements of Heat Transfer, Flow, and Pressures in a Simulated Turbine Blade Internal Cooling Passage

NASA Technical Reports Server (NTRS)

Russell, Louis M.; Thurman, Douglas R.; Poinsatte, Philip E.; Hippensteele, Steven A.

1998-01-01

An experimental study was made to obtain quantitative information on heat transfer, flow, and pressure distribution in a branched duct test section that had several significant features of an internal cooling passage of a turbine blade. The objective of this study was to generate a set of experimental data that could be used for validation of computer codes that would be used to model internal cooling. Surface heat transfer coefficients and entrance flow conditions were measured at nominal entrance Reynolds numbers of 45,000, 335,000, and 726,000. Heat transfer data were obtained by using a steady-state technique in which an Inconel heater sheet is attached to the surface and coated with liquid crystals. Visual and quantitative flow-field data from particle image velocimetry measurements for a plane at midchannel height for a Reynolds number of 45,000 were also obtained. The flow was seeded with polystyrene particles and illuminated by a laser light sheet. Pressure distribution measurements were made both on the surface with discrete holes and in the flow field with a total pressure probe. The flow-field measurements yielded flow-field velocities at selected locations. A relatively new method, pressure sensitive paint, was also used to measure surface pressure distribution. The pressure paint data obtained at Reynolds numbers of 335,000 and 726,000 compared well with the more standard method of measuring pressures by using discrete holes.