Science.gov

Sample records for lasker foundation clinical

  1. Researchers Win Coveted Lasker Awards.

    PubMed

    2015-11-01

    In recognition of work that led to a greater understanding of genetics and biology-and to new treatments for cancer-the Lasker Foundation bestowed its prestigious awards on renowned genetic researchers Evelyn M. Witkin, PhD, and Stephen J. Elledge, PhD, and immunologist James P. Allison, PhD, in September.

  2. Measuring revolutionary biomedical science 1992-2006 using Nobel prizes, Lasker (clinical medicine) awards and Gairdner awards (NLG metric).

    PubMed

    Charlton, Bruce G

    2007-01-01

    The Nobel prize for medicine or physiology, the Lasker award for clinical medicine, and the Gairdner international award are given to individuals for their role in developing theories, technologies and discoveries which have changed the direction of biomedical science. These distinctions have been used to develop an NLG metric to measure research performance and trends in 'revolutionary' biomedical science with the aim of identifying the premier revolutionary science research institutions and nations from 1992-2006. I have previously argued that the number of Nobel laureates in the biomedical field should be expanded to about nine per year and the NLG metric attempts to predict the possible results of such an expansion. One hundred and nineteen NLG prizes and awards were made during the past fifteen years (about eight per year) when overlapping awards had been removed. Eighty-five were won by the USA, revealing a massive domination in revolutionary biomedical science by this nation; the UK was second with sixteen awards; Canada had five, Australia four and Germany three. The USA had twelve elite centres of revolutionary biomedical science, with University of Washington at Seattle and MIT in first position with six awards and prizes each; Rockefeller University and Caltech were jointly second placed with five. Surprisingly, Harvard University--which many people rank as the premier world research centre--failed to reach the threshold of three prizes and awards, and was not included in the elite list. The University of Oxford, UK, was the only institution outside of the USA which featured as a significant centre of revolutionary biomedical science. Long-term success at the highest level of revolutionary biomedical science (and probably other sciences) probably requires a sufficiently large number of individually-successful large institutions in open competition with one another--as in the USA. If this model cannot be replicated within smaller nations, then it implies

  3. Heart Pump Design for Cleveland Clinic Foundation

    NASA Technical Reports Server (NTRS)

    2005-01-01

    Through a Lewis CommTech Program project with the Cleveland Clinic Foundation, the NASA Lewis Research Center is playing a key role in the design and development of a permanently implantable, artificial heart pump assist device. Known as the Innovative Ventricular Assist System (IVAS), this device will take on the pumping role of the damaged left ventricle of the heart. The key part of the IVAS is a nonpulsatile (continuous flow) artificial heart pump with centrifugal impeller blades, driven by an electric motor. Lewis is part of an industry and academia team, led by the Ohio Aerospace Institute (OAI), that is working with the Cleveland Clinic Foundation to make IVAS a reality. This device has the potential to save tens of thousands of lives each year, since 80 percent of heart attack victims suffer irreversible damage to the left ventricle, the part of the heart that does most of the pumping. Impeller blade design codes and flow-modeling analytical codes will be used in the project. These codes were developed at Lewis for the aerospace industry but will be applicable to the IVAS design project. The analytical codes, which currently simulate the flow through the compressor and pump systems, will be used to simulate the flow within the blood pump in the artificial heart assist device. The Interdisciplinary Technology Office heads up Lewis' efforts in the IVAS project. With the aid of numerical modeling, the blood pump will address many design issues, including some fluid-dynamic design considerations that are unique to the properties of blood. Some of the issues that will be addressed in the design process include hemolysis, deposition, recirculation, pump efficiency, rotor thrust balance, and bearing lubrication. Optimum pumping system performance will be achieved by modeling all the interactions between the pump components. The interactions can be multidisciplinary and, therefore, are influenced not only by the fluid dynamics of adjacent components but also by

  4. Conciliating cognition and consciousness: the perceptual foundations of clinical reasoning.

    PubMed

    Braude, Hillel D

    2012-10-01

    Clinical reasoning has been defined as a form of cognition applied to evaluating and managing a patient's medical problem. As a kind of cognition, a product of the human psyche, it is logical to expect that clinical reasoning should be best understood through methods derived from psychology, neuropsychology and the cognitive sciences. However, the application of scientific methods to evaluating clinical reasoning is unable to analyse clinical reasoning in terms of first-person experience and consciousness. By reducing clinical reasoning to its cognitive components the cognitivist approach tends to ignore the larger context in which clinical reasoning occurs. By reducing its conception of clinical reasoning to its cognitive components, the neuropsychological approach fails to acknowledge clinical reasoning as a form of intentionality, a gestalt, grounded in human perception. A full epistemology of clinical reasoning requires a phenomenological analysis that can make sense of the relation between pre-reflective consciousness and explicit forms of knowing. In this paper I conciliate cognition and consciousness in medicine through analysing the phenomenology of perception in clinical reasoning. I compare the application of phenomenology to clinical reasoning with the attempt to model clinical reasoning on Aristotelian practical wisdom or phronesis. Finally, I analyse empathy as a type of perception critical for effective clinical interaction and exemplary for reflecting on perception as the intersubjective foundation of clinical reasoning.

  5. [Foundational questions in the beginning of clinical psychology].

    PubMed

    Ceccarelli, Glauco

    2013-01-01

    This work proposes an initial survey on the origins of American clinical psychology between the nineteenth and twentieth century, against a backdrop of historiographical interpretation that hypothesizes a "plurality of matrices" of clinical psychology, linked to different theoretical perspectives and different socio-cultural contexts. Particular attention is focused upon the main foundational issues of the discipline, drawing from some of the writings of Lightner Witmer, to whom we owe the founding of the first "clinical psychology" for subjects in childhood characterized by "retardation or physical defects interfering with school progress"; and of a lesser-known scholar, John E.W. Wallin. Both authors, indeed, worry themselves anxious to define clinical psychology, differentiating it from other medical and psychological branches; to establish which is the field of competence of the clinical psychologist; and to outline their training and specify the aims and contents of their intervention. Attention is then addressed to the relationship psychologists-psychiatrists at the time of its emergence, making specific reference to a document of the New York Psychiatrical Society--which represents one of the first attempts to exclude clinical psychologists from the field of mental health--and reporting also on the response to this position signed by Shepherd Franz. After an allusion to the Italian situation from the 1950s to today, the article concludes by emphasizing that at least some of the basic questions that clinical psychology had to deal with at its birth are still present, though filtered through the intense debate that has taken place over the years, and consequently supporting the importance of a historical component in the training of contemporary clinical psychologists.

  6. Chapter 12: the anatomical foundations of clinical neurology.

    PubMed

    Bentivoglio, Marina; Mazzarello, Paolo

    2010-01-01

    The chapter provides an itinerary of knowledge on nervous system anatomy as one of the pillars of clinical neurology. The journey starts from the Renaissance explosion on the approach to the human body, its functions and its diseases, dealing with the seminal contributions of Leonardo da Vinci and Vesalius. The itinerary proceeds through the contributions of the 17th century, especially by Thomas Willis and the pioneering investigations of Marcello Malpighi and Antony van Leeuwenhoek, and onto the 18th century. The itinerary thus leads to the progress from gross anatomy to the microscopic investigation of the nervous system in the 19th century: the reticular theories, the revolution of the neural doctrine and their protagonists (Camillo Golgi and Santiago Ramón y Cajal), which initiated the modern era of the neurosciences. The chapter also includes sections on the contributions of developmental neuroanatomy to neurology, on the history of tract tracing, and on the cytoarchitecture of the cerebral cortex. The never-ending story of the anatomical foundations of clinical neurology continues to evolve at the dawn of the 21st century, including knowledge that guides deep brain stimulation, and novel approaches to the anatomy of the living brain based on rapidly developing neuroimaging technology.

  7. Foundations

    NASA Astrophysics Data System (ADS)

    Harteveld, Casper

    A building will more likely collapse if it does not have any proper foundations. Similarly, the design philosophy of Triadic Game Design (TGD) needs to reside on solid building blocks, otherwise the concept will collapse as well. In this level I will elaborate on these building blocks. First I will explain what the general idea of TGD is. It is a design philosophy, for sure, but one which stresses that an “optimum” needs to be found in a design space constituted by three different worlds: Reality, Meaning, and Play. Additionally, these worlds need to be considered simultaneously and be treated equally. The latter requires balancing the worlds which may result in different tensions, within and between two or three of the worlds. I continue by discussing each of the worlds and showing their perspective on the field of games with a meaningful purpose. From this, we clearly see that it is feasible to think of each world and that the idea makes sense. I substantiate this further by relating the notion of player and similar approaches to this framework. This level is quite a tough pill to swallow yet essential for finishing the other levels. Do not cheat or simply skip this level, but just take a big cup of coffee or tea and start reading it.

  8. The Ontology of Clinical Research (OCRe): An Informatics Foundation for the Science of Clinical Research

    PubMed Central

    Sim, Ida; Tu, Samson W.; Carini, Simona; Lehmann, Harold P.; Pollock, Brad H.; Peleg, Mor; Wittkowski, Knut M.

    2013-01-01

    To date, the scientific process for generating, interpreting, and applying knowledge has received less informatics attention than operational processes for conducting clinical studies. The activities of these scientific processes — the science of clinical research — are centered on the study protocol, which is the abstract representation of the scientific design of a clinical study. The Ontology of Clinical Research (OCRe) is an OWL 2 model of the entities and relationships of study design protocols for the purpose of computationally supporting the design and analysis of human studies. OCRe’s modeling is independent of any specific study design or clinical domain. It includes a study design typology and a specialized module called ERGO Annotation for capturing the meaning of eligibility criteria. In this paper, we describe the key informatics use cases of each phase of a study’s scientific lifecycle, present OCRe and the principles behind its modeling, and describe applications of OCRe and associated technologies to a range of clinical research use cases. OCRe captures the central semantics that underlies the scientific processes of clinical research and can serve as an informatics foundation for supporting the entire range of knowledge activities that constitute the science of clinical research. PMID:24239612

  9. Aquatic therapy: scientific foundations and clinical rehabilitation applications.

    PubMed

    Becker, Bruce E

    2009-09-01

    The aquatic environment has broad rehabilitative potential, extending from the treatment of acute injuries through health maintenance in the face of chronic diseases, yet it remains an underused modality. There is an extensive research base supporting aquatic therapy, both within the basic science literature and clinical literature. This article describes the many physiologic changes that occur during immersion as applied to a range of common rehabilitative issues and problems. Because of its wide margin of therapeutic safety and clinical adaptability, aquatic therapy is a very useful tool in the rehabilitative toolbox. Through a better understanding of the applied physiology, the practitioner may structure appropriate therapeutic programs for a diverse patient population.

  10. After-Hours Access to the Cleveland Clinic Foundation Library Services Department: An Examination of Services.

    ERIC Educational Resources Information Center

    Bouria, Deanne Daniels

    This study was launched to address concerns about the needs of after-hours users going unmet at the Cleveland (Ohio) Clinic Foundation Library Services Department. The collection itself is available for use on the premises by clinic employees 24 hours a day, but employees do not remain on site to provide assistance, materials may not be signed out…

  11. [Clinical autopsies. Practical approach, legal foundations and ethical considerations].

    PubMed

    Friemann, J

    2010-07-01

    Only an autopsy can demonstrate topographical and morphological circumstances in detail and correlate the clinical and autopsy findings based on the examination of all organs. The practical approach in a fatality is described based on the example of the Lüdenscheid Hospital. A uniform legal regulation for dealing with corpses does not exist in Germany. There are two approaches to the question under which circumstances a clinical autopsy is allowed: the extended permission solution and the objection solution. Whether a clinical autopsy can be carried out is decided by the medical specialist selected on application. Autopsies can be necessary from insurance or administrative legal grounds or in the case of an anatomical autopsy is decided by the persons themselves. In order to guarantee the quality of an autopsy it is necessary to use a standardized approach with evaluation and assessment of the results, for example using a quality assurance protocol and the production of an autopsy report. Using this approach important information can be gained not only on the accuracy of the main diagnosis and cause of death but also on additional diseases, response to therapy and the course of the disease and under circumstances can lead to modifications in the approach.

  12. 78 FR 35638 - Certificate of Alternative Compliance for the NOAA Research Vessel FSV-6 RUBEN LASKER, 9664988

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-13

    .... 1605(c) and 33 CFR 81.18. DATES: The Certificate of Alternative Compliance was issued on December 20... 33 U.S.C. 1605(c) and 33 CFR 81.18, has been issued for the NOAA research vessel FSV-6 RUBEN LASKER...), and 33 CFR 81.18. Dated: May 10, 2013. S.E. Anderson, Commander, U.S. Coast Guard, Acting...

  13. Which are the best nations and institutions for revolutionary science 1987-2006? Analysis using a combined metric of Nobel prizes, Fields medals, Lasker awards and Turing awards (NFLT metric).

    PubMed

    Charlton, Bruce G

    2007-01-01

    I have previously suggested that Nobel prizes can be used as a scientometric measurement of 'revolutionary science'; and that for this purpose it would be better if more Nobel prizes were awarded, especially in three new subjects of mathematics, medicine and computing science which have become major sciences over recent decades. In the following analysis of the last 20 years from 1987 to 2006, I use three prestigious prizes in mathematics (Fields medal), medicine (Lasker award for Clinical Medical Research) and computing science (A.M. Turing award) which are plausible surrogates for Nobel prizes. The combined Nobel-Fields-Lasker-Turing (NFLT) metric is strongly dominated by the USA. However the distribution implies that revolutionary science may be somewhat more broadly distributed than the pure Nobel metric suggests. The UK and France seem to be significant nations in some types of revolutionary science (although the UK has declined substantially as a centre of revolutionary science); and Germany, Switzerland, Japan, Russia, Denmark and Norway also feature. The top world institutions for revolutionary science according to NFLT are MIT, Stanford and Princeton - all in the USA - and the USA has 19 institutions with at least three prize-winners. Second is France, with three institutions having three or more winners; the UK and Norway have one each. The NFLT metric confirms previous observations that many public universities in the Western USA have now become a major focus of revolutionary science; and that Harvard has declined from its previous status as the top world centre of revolutionary science to about seventh-place. This analysis confirms the potential value of increasing the number of Nobel prizes as a means of identifying and monitoring centres of excellence in revolutionary science. PMID:17234353

  14. IBM Application System/400 as the foundation of the Mayo Clinic/IBM PACS project

    NASA Astrophysics Data System (ADS)

    Rothman, Melvyn L.; Morin, Richard L.; Persons, Kenneth R.; Gibbons, Patricia S.

    1990-08-01

    An IBM Application System/400 (AS/400) anchors the Mayo Clinic/IBM joint development PACS project. This paper highlights some of the AS/400's features and the resulting benefits which make it a strong foundation for a medical image archival and review system. Among the AS/400's key features are: 1. A high-level machine architecture 2. Object orientation 3. Relational data base and other functions integrated into the system's architecture 4. High-function interfaces to IBM Personal Computers and IBM Personal System/2s' (pS/2TM).

  15. Key findings of the US Cystic Fibrosis Foundation's clinical practice benchmarking project.

    PubMed

    Boyle, Michael P; Sabadosa, Kathryn A; Quinton, Hebe B; Marshall, Bruce C; Schechter, Michael S

    2014-04-01

    Benchmarking is the process of using outcome data to identify high-performing centres and determine practices associated with their outstanding performance. The US Cystic Fibrosis Foundation (CFF) Patient Registry contains centre-specific outcomes data for all CFF-certified paediatric and adult cystic fibrosis (CF) care programmes in the USA. The CFF benchmarking project analysed these registry data, adjusting for differences in patient case mix known to influence outcomes, and identified the top-performing US paediatric and adult CF care programmes for pulmonary and nutritional outcomes. Separate multidisciplinary paediatric and adult benchmarking teams each visited 10 CF care programmes, five in the top quintile for pulmonary outcomes and five in the top quintile for nutritional outcomes. Key practice patterns and approaches present in both paediatric and adult programmes with outstanding clinical outcomes were identified and could be summarised as systems, attitudes, practices, patient/family empowerment and projects. These included: (1) the presence of strong leadership and a well-functioning care team working with a systematic approach to providing consistent care; (2) high expectations for outcomes among providers and families; (3) early and aggressive management of clinical declines, avoiding reliance on 'rescues'; and (4) patients/families that were engaged, empowered and well informed on disease management and its rationale. In summary, assessment of practice patterns at CF care centres with top-quintile pulmonary and nutritional outcomes provides insight into characteristic practices that may aid in optimising patient outcomes.

  16. Adaptive control of drug dosage regimens: basic foundations, relevant issues, and clinical examples.

    PubMed

    Jelliffe, R W; Maire, P; Sattler, F; Gomis, P; Tahani, B

    1994-06-01

    In this paper we examine several of the fundamental foundations and relevant clinical issues in adaptive control of drug dosage regimens for patients. Truly individualized therapy with drugs having narrow margins of safety first requires a practical pharmacokinetic/dynamic model of the behavior of a drug. Past experience with a drug is stored in the form of a population model. Next, using the information in such a model and its relationship to the incidence of adverse reactions, a specific, explicit therapeutic goal must be selected by the responsible clinician, based on the patient's need for the drug and the risk of adverse reactions felt to be justified by each patient's need, small, moderate, or great. Individualized drug therapy thus begins with the selection of individualized therapeutic goals (low, moderate, or high) for each patient. Using subsequent feedback from the patient's serum drug levels, and using Bayesian fitting, the model is then linked to each patient as a patient-specific model. Control of the model by the dosage regimen increasingly controls the patient, to better obtain the desired explicit therapeutic goals. This process is essentially similar to that of a flight control or missile guidance system.

  17. Interpretation and use of FRAX in clinical practice - position paper of the International Osteoporosis Foundation and the International Society for Clinical Densitometry

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The International Osteoporosis Foundation (IOF) and the International Society for Clinical Densitometry (ISCD) appointed a joint Task Force to develop resource documents in order to make recommendations on how to improve FRAX and better inform clinicians who use FRAX. The Task Force met in November...

  18. The American Society of Clinical Oncology Cancer Foundation Grants Program: a 25-year report and a look toward the future.

    PubMed

    King, Jennifer C; Lawrence, Theodore S; Murphy, Sharon B; Davidson, Nancy E; Mayer, Robert J

    2010-03-20

    The American Society of Clinical Oncology (ASCO) Grants Program began in 1984 with a single $16,000 grant to a young investigator for start-up research funding. In 2009, the Grants Program, now administered by The ASCO Cancer Foundation, awarded more than $6.5 million to 70 different investigators. This article, celebrating the 25th anniversary of this initiative, describes the history and evolution of the Grants Program, attempts to measure the impact of the program on clinical cancer research through an analysis of the career paths of past recipients, and addresses challenges that the program will face as it enters its second 25 years.

  19. A qualitative evaluation of foundation dentists' and training programme directors' perceptions of clinical audit in general dental practice.

    PubMed

    Thornley, P; Quinn, A; Elley, K

    2015-08-28

    This study reports on an investigation into clinical audit (CA) educational and service delivery outcomes in a dental foundation training (DFT) programme. The aim was to investigate CA teaching, learning and practice from the perspective of foundation dentists (FDs) and to record suggestions for improvement. A qualitative research methodology was used. Audio recordings of focus group interviews with FDs were triangulated by an interview with a group of training programme directors (TPDs). The interviews were transcribed and thematically analysed using a 'Framework' approach within Nvivo Data Analysis Software. FDs report considerable learning and behaviour change. However, TPDs have doubts about the long-term effects on service delivery. There can be substantial learning in the clinical, managerial, communication and professionalism domains, and in the development of time management, organisational and team-working skills. Information is provided about use of resources and interaction with teachers and colleagues. CA provides learning opportunities not produced by other educational activities including 'awkward conversations' with team-members in the context of change management and providing feedback. This is relevant when applying the recommendations of the Francis report. This paper should be useful to any dentist conducting audit or team training. Suggestions are made for improvements to resources and support including right touch intervention. Trainers should teach in the 'Goldilocks Zone'. PMID:26315182

  20. Historical review of clinical vaccine studies at Oswaldo Cruz Institute and Oswaldo Cruz Foundation - technological development issues

    PubMed Central

    Martins, Reinaldo de Menezes; Possas, Cristina de Albuquerque; Homma, Akira

    2015-01-01

    This paper presents, from the perspective of technological development and production, the results of an investigation examining 61 clinical studies with vaccines conducted in Brazil between 1938-2013, with the participation of the Oswaldo Cruz Institute (IOC) and the Oswaldo Cruz Foundation (Fiocruz). These studies have been identified and reviewed according to criteria, such as the kind of vaccine (viral, bacterial, parasitic), their rationale, design and methodological strategies. The results indicate that IOC and Fiocruz have accumulated along this time significant knowledge and experience for the performance of studies in all clinical phases and are prepared for the development of new vaccines products and processes. We recommend national policy strategies to overcome existing regulatory and financing constraints. PMID:25742271

  1. Inter-Observer Reliability Assessments in Time Motion Studies: The Foundation for Meaningful Clinical Workflow Analysis

    PubMed Central

    Lopetegui, Marcelo A.; Bai, Shasha; Yen, Po-Yin; Lai, Albert; Embi, Peter; Payne, Philip R.O.

    2013-01-01

    Understanding clinical workflow is critical for researchers and healthcare decision makers. Current workflow studies tend to oversimplify and underrepresent the complexity of clinical workflow. Continuous observation time motion studies (TMS) could enhance clinical workflow studies by providing rich quantitative data required for in-depth workflow analyses. However, methodological inconsistencies have been reported in continuous observation TMS, potentially reducing the validity of TMS’ data and limiting their contribution to the general state of knowledge. We believe that a cornerstone in standardizing TMS is to ensure the reliability of the human observers. In this manuscript we review the approaches for inter-observer reliability assessment (IORA) in a representative sample of TMS focusing on clinical workflow. We found that IORA is an uncommon practice, inconsistently reported, and often uses methods that provide partial and overestimated measures of agreement. Since a comprehensive approach to IORA is yet to be proposed and validated, we provide initial recommendations for IORA reporting in continuous observation TMS. PMID:24551381

  2. ASSESSMENT OF UPPER EXTREMITY IMPAIRMENT, FUNCTION, AND ACTIVITY FOLLOWING STROKE: FOUNDATIONS FOR CLINICAL DECISION MAKING

    PubMed Central

    Lang, Catherine E.; Bland, Marghuretta D.; Bailey, Ryan R.; Schaefer, Sydney Y.; Birkenmeier, Rebecca L.

    2012-01-01

    The purpose of this review is to provide a comprehensive approach for assessing the upper extremity (UE) after stroke. First, common upper extremity impairments and how to assess them are briefly discussed. While multiple UE impairments are typically present after stroke, the severity of one impairment, paresis, is the primary determinant of UE functional loss. Second, UE function is operationally defined and a number of clinical measures are discussed. It is important to consider how impairment and loss of function affect UE activity outside of the clinical environment. Thus, this review also identifies accelerometry as an objective method for assessing UE activity in daily life. Finally, the role that each of these levels of assessment should play in clinical decision making is discussed in order to optimize the provision of stroke rehabilitation services. PMID:22975740

  3. Observation of Couple Conflicts: Clinical Assessment Applications, Stubborn Truths, and Shaky Foundations

    PubMed Central

    Heyman, Richard E.

    2006-01-01

    The purpose of this review is to provide a balanced examination of the published research involving the observation of couples, with special attention toward the use of observation for clinical assessment. All published articles that (a) used an observational coding system and (b) relate to the validity of the coding system are summarized in a table. The psychometric properties of observational systems and the use of observation in clinical practice are discussed. Although advances have been made in understanding couple conflict through the use of observation, the review concludes with an appeal to the field to develop constructs in a psychometrically and theoretically sound manner. PMID:11281039

  4. Clinical manufacturing of CAR T cells: foundation of a promising therapy.

    PubMed

    Wang, Xiuyan; Rivière, Isabelle

    2016-01-01

    The treatment of cancer patients with autologous T cells expressing a chimeric antigen receptor (CAR) is one of the most promising adoptive cellular therapy approaches. Reproducible manufacturing of high-quality, clinical-grade CAR-T cell products is a prerequisite for the wide application of this technology. Product quality needs to be built-in within every step of the manufacturing process. We summarize herein the requirements and logistics to be considered, as well as the state of the art manufacturing platforms available. CAR-T cell therapy may be on the verge of becoming standard of care for a few clinical indications. Yet, many challenges pertaining to manufacturing standardization and product characterization remain to be overcome in order to achieve broad usage and eventual commercialization of this therapeutic modality. PMID:27347557

  5. Clinical manufacturing of CAR T cells: foundation of a promising therapy

    PubMed Central

    Wang, Xiuyan; Rivière, Isabelle

    2016-01-01

    The treatment of cancer patients with autologous T cells expressing a chimeric antigen receptor (CAR) is one of the most promising adoptive cellular therapy approaches. Reproducible manufacturing of high-quality, clinical-grade CAR-T cell products is a prerequisite for the wide application of this technology. Product quality needs to be built-in within every step of the manufacturing process. We summarize herein the requirements and logistics to be considered, as well as the state of the art manufacturing platforms available. CAR-T cell therapy may be on the verge of becoming standard of care for a few clinical indications. Yet, many challenges pertaining to manufacturing standardization and product characterization remain to be overcome in order to achieve broad usage and eventual commercialization of this therapeutic modality. PMID:27347557

  6. Recent Clinical Trials in Osteoporosis: A Firm Foundation or Falling Short?

    PubMed

    Barnard, Karen; Lakey, Wanda C; Batch, Bryan C; Chiswell, Karen; Tasneem, Asba; Green, Jennifer B

    2016-01-01

    The global burden of osteoporotic fractures is associated with significant morbidity, mortality, and healthcare costs. We examined the ClinicalTrials.gov database to determine whether recently registered clinical trials addressed prevention and treatment in those at high risk for fracture. A dataset of 96,346 trials registered in ClinicalTrials.gov was downloaded on September 27, 2010. At the time of the dataset download, 40,970 interventional trials had been registered since October 1, 2007. The osteoporosis subset comprised 239 interventional trials (0.6%). Those trials evaluating orthopedic procedures were excluded. The primary purpose was treatment in 67.0%, prevention in 20.1%, supportive care in 5.8%, diagnostic in 2.2%, basic science in 3.1%, health services research in 0.9%, and screening in 0.9%. The majority of studies (61.1%) included drug-related interventions. Most trials (56.9%) enrolled only women, 38.9% of trials were open to both men and women, and 4.2% enrolled only men. Roughly one fifth (19.7%) of trials excluded research participants older than 65 years, and 33.5% of trials excluded those older than 75 years. The funding sources were industry in 51.0%, the National Institutes of Health in 6.3%, and other in 42.7%. We found that most osteoporosis-related trials registered from October 2007 through September 2010 examined the efficacy and safety of drug treatment, and fewer trials examined prevention and non-drug interventions. Trials of interventions that are not required to be registered in ClinicalTrials.gov may be underrepresented. Few trials are specifically studying osteoporosis in men and older adults. Recently registered osteoporosis trials may not sufficiently address fracture prevention. PMID:27191848

  7. Epilepsy Foundation

    MedlinePlus

    ... Gastaut Syndrome Infantile Spasms and Tuberous Sclerosis Complex Facebook < > Epilepsy Foundation of America Watch the next George ... consider the Epilepsy Foundation your #UnwaveringAlly on Twitter, Facebook, and Instagram! Epilepsy Foundation of America Star Trek ...

  8. Sympathetic Resonance Technology: scientific foundation and summary of biologic and clinical studies.

    PubMed

    Rubik, Beverly

    2002-12-01

    Sympathetic Resonance Technology (SRT; Clarus Products, International, L.L.C., San Rafael, CA) is a novel technology used in consumer health care products to protect humans from the potentially harmful effects of stress. A summary of the previously unpublished studies on SRT, both basic and clinical, is presented. These studies collectively show that SRT mitigates the stress response for a variety of stressors such as chemical and electromagnetic stress in various biologic systems and multiple levels of organization, ranging from the molecular to the behavioral. A rudimentary model of how SRT may work at the level of the biofield, the endogenous electromagnetic field of the organism, is proposed. By interacting with key component frequencies in the biofield, SRT may stabilize the organism homeodynamically, thereby protecting it from the effects of stressful stimuli.

  9. National Kidney Foundation Council on Renal Nutrition survey: past-present clinical practices and future strategic planning.

    PubMed

    Moore, Harold; Reams, Susan M; Wiesen, Karen; Nolph, Karl D; Khanna, Ramesh; Laothong, Chonwit

    2003-07-01

    Early nutritional intervention is thought to play a major role in the preservation of renal function and the overall wellbeing in the renal patient. In preparation for renal replacement therapy (RRT), a consultation with the renal nutritionist to establish a diet consistent with the existing diagnosis may increase the likelihood of reducing cardiovascular risk factors, preventing malnutrition and anemia, and slowing the progression of renal disease, all of which can contribute to positive patient outcomes. In a 1999 United States Renal Data System survey of 3,468 new dialysis patients, 46% indicated that they had not consulted with a dietitian before the initiation of dialysis. To help with establishing education programs, determine staffing guidelines, and planning future endeavors, the National Kidney Foundation Council on Renal Nutrition conducted a survey of their 1,748 members. The survey was designed to assess the current demographic profile and clinical practice elements of practicing renal dietitians. Surveys were distributed as a section of the 1999-2000 winter issue of the CRN Quarterly Newsletter, with 353 of the members responding. Information collected pertained to patient care settings, number of facilities covered, patient age, patient treatment modalities, dietitian contact hours required to effectively educate pre-end-stage renal disease patients on a low-protein diet and to ensure optimal nutrition status for the chronic kidney disease patients. The dietitians of this cohort had practiced dietetics for 14.5 +/- 8.6 years and renal nutrition for 9.15 +/- 6.9 years. The survey data showed a discrepancy between what the clinical practices were in 1999 and what the current recommendations are, based on the Kidney Disease Outcomes Quality Initiatives (K/DOQI) Clinical Practice Guidelines. PMID:12874750

  10. Considerations for the Conduct of Clinical Trials with Antiinflammatory Agents in Cystic Fibrosis. A Cystic Fibrosis Foundation Workshop Report.

    PubMed

    Torphy, Theodore J; Allen, Janet; Cantin, André M; Konstan, Michael W; Accurso, Frank J; Joseloff, Elizabeth; Ratjen, Felix A; Chmiel, James F

    2015-09-01

    Inflammation leads to lung destruction and loss of pulmonary function in patients with cystic fibrosis (CF). Drugs that modulate the cystic fibrosis transmembrane conductance regulator (CFTR) have recently been approved. Although the impact of CFTR modulators on sweat chloride and lung function are exciting, they have not yet demonstrated an effect on inflammation. Therefore, CF antiinflammatory drug development must continue. Unfortunately, the lack of clarity with this process has left investigators and industry sponsors frustrated. The Cystic Fibrosis Foundation established a working group in early 2014 to address this issue. There are many inflammatory processes disrupted in CF, and, therefore, there are many potential targets amenable to antiinflammatory therapy. Regardless of a drug's specific mechanism of action, it must ultimately affect the neutrophil or its products to impact CF. The working group concluded that before bringing new antiinflammatory drugs to clinical trial, preclinical safety studies must be conducted in disease-relevant models to assuage safety concerns. Furthermore, although studies of antiinflammatory therapies must first establish safety in adults, subsequent studies must involve children, as they are most likely to reap the most benefit. The working group also recommended that pharmacokinetic-pharmacodynamic studies and early-phase safety studies be performed before proceeding to larger studies of longer duration. In addition, innovative study designs may improve the likelihood of adequately assessing treatment response and mitigating risk before conducting multiyear studies. Learning from past experiences and incorporating this knowledge into new drug development programs will be instrumental in bringing new antiinflammatory therapies to patients.

  11. Clinical Outcome Assessments: Conceptual Foundation-Report of the ISPOR Clinical Outcomes Assessment - Emerging Good Practices for Outcomes Research Task Force.

    PubMed

    Walton, Marc K; Powers, John H; Hobart, Jeremy; Patrick, Donald; Marquis, Patrick; Vamvakas, Spiros; Isaac, Maria; Molsen, Elizabeth; Cano, Stefan; Burke, Laurie B

    2015-09-01

    An outcome assessment, the patient assessment used in an endpoint, is the measuring instrument that provides a rating or score (categorical or continuous) that is intended to represent some aspect of the patient's health status. Outcome assessments are used to define efficacy endpoints when developing a therapy for a disease or condition. Most efficacy endpoints are based on specified clinical assessments of patients. When clinical assessments are used as clinical trial outcomes, they are called clinical outcome assessments (COAs). COAs include any assessment that may be influenced by human choices, judgment, or motivation. COAs must be well-defined and possess adequate measurement properties to demonstrate (directly or indirectly) the benefits of a treatment. In contrast, a biomarker assessment is one that is subject to little, if any, patient motivational or rater judgmental influence. This is the first of two reports by the ISPOR Clinical Outcomes Assessment - Emerging Good Practices for Outcomes Research Task Force. This report provides foundational definitions important for an understanding of COA measurement principles. The foundation provided in this report includes what it means to demonstrate a beneficial effect, how assessments of patients relate to the objective of showing a treatment's benefit, and how these assessments are used in clinical trial endpoints. In addition, this report describes intrinsic attributes of patient assessments and clinical trial factors that can affect the properties of the measurements. These factors should be considered when developing or refining assessments. These considerations will aid investigators designing trials in their choice of using an existing assessment or developing a new outcome assessment. Although the focus of this report is on the development of a new COA to define endpoints in a clinical trial, these principles may be applied more generally. A critical element in appraising or developing a COA is to

  12. Clinical Outcome Assessments: Conceptual Foundation-Report of the ISPOR Clinical Outcomes Assessment - Emerging Good Practices for Outcomes Research Task Force.

    PubMed

    Walton, Marc K; Powers, John H; Hobart, Jeremy; Patrick, Donald; Marquis, Patrick; Vamvakas, Spiros; Isaac, Maria; Molsen, Elizabeth; Cano, Stefan; Burke, Laurie B

    2015-09-01

    An outcome assessment, the patient assessment used in an endpoint, is the measuring instrument that provides a rating or score (categorical or continuous) that is intended to represent some aspect of the patient's health status. Outcome assessments are used to define efficacy endpoints when developing a therapy for a disease or condition. Most efficacy endpoints are based on specified clinical assessments of patients. When clinical assessments are used as clinical trial outcomes, they are called clinical outcome assessments (COAs). COAs include any assessment that may be influenced by human choices, judgment, or motivation. COAs must be well-defined and possess adequate measurement properties to demonstrate (directly or indirectly) the benefits of a treatment. In contrast, a biomarker assessment is one that is subject to little, if any, patient motivational or rater judgmental influence. This is the first of two reports by the ISPOR Clinical Outcomes Assessment - Emerging Good Practices for Outcomes Research Task Force. This report provides foundational definitions important for an understanding of COA measurement principles. The foundation provided in this report includes what it means to demonstrate a beneficial effect, how assessments of patients relate to the objective of showing a treatment's benefit, and how these assessments are used in clinical trial endpoints. In addition, this report describes intrinsic attributes of patient assessments and clinical trial factors that can affect the properties of the measurements. These factors should be considered when developing or refining assessments. These considerations will aid investigators designing trials in their choice of using an existing assessment or developing a new outcome assessment. Although the focus of this report is on the development of a new COA to define endpoints in a clinical trial, these principles may be applied more generally. A critical element in appraising or developing a COA is to

  13. ABIM Foundation

    MedlinePlus

    ... ON TWITTER ABIM Foundation ABIM Foundation is using Facebook to share helpful information. We welcome comments, ideas, ... the conventions of civil discourse and comply with Facebook Terms of Use. While we encourage fans to ...

  14. Dysautonomia Foundation

    MedlinePlus

    ... More about FD .) Research funded by the Dysautonomia Foundation has led to a number of breakthroughs in ... our FD screening awareness video here .) The Dysautonomia Foundation is a 501c3 nonprofit organization that has established ...

  15. Marfan Foundation

    MedlinePlus

    ... Foundation Brings its 32nd Annual Conference to Rochester, MN, August 4-7, 2016 The Marfan Foundation will hold its 32nd Annual Conference in Rochester, MN, on August 4-7. The conference, organized in ...

  16. Reporting of adverse event data in hematopoietic stem cell transplantation clinical trials involving investigational new drugs or devices: a report from the William Guy Forbeck Foundation 2001 focus meeting on clinical trials in hematopoietic stem cell transplantation.

    PubMed

    Martin, Paul J; Antin, Joseph H; Weisdorf, Daniel J; Paton, Virginia; Horowitz, Mary M

    2002-01-01

    The William Guy Forbeck Foundation was established in 1984 in memory of William Guy Forbeck, an 11-year-old boy who died of neuroblastoma. The objectives of the Forbeck Foundation are to promote advances and shorten the research timetable in the field of oncology, particularly pediatric oncology. The Foundation's centerpiece activity is an annual scientific forum held at Hilton Head Island, South Carolina, where 12 to 15 leading scientists from a variety of disciplines associated with a specific topic are invited to participate in a private "think tank" environment, where they can freely exchange ideas in the hope of building on each other's knowledge and experience. Additionally, the Foundation sponsors grants for Focus Meetings, which are designed to give other researchers an opportunity to conduct their own meetings along the lines of the Foundation's annual forum. The idea for this Focus Meeting was born during the 2000 Annual Forbeck Forum in South Carolina, which considered the current status of allogeneic hematopoietic stem cell transplantation (HSCT). Participants considered various obstacles to conducting clinical trials in this area and decided to bring together experts from academia, industry, and government to discuss ways in which these obstacles might be overcome. Topics included efficient clinical trial designs, issues of monitoring and reporting adverse events, and appropriate definitions and grading systems for transplantation-specific outcomes. This article summarizes the issue of adverse event reporting in HSCT.

  17. Use of an alternative pontic foundation technique for a fiber-reinforced composite fixed partial denture: a clinical report.

    PubMed

    Ayna, Emrah; Celenk, Sema

    2005-05-01

    This article describes the treatment of a patient for whom a fiber-composite laminate dowel and core and polyethylene fiber were used as a conservative alternative to provide a dowel-and-core and fixed partial denture foundation. The treatment plan included removing the existing restoration on the maxillary right first molar, placing a fiber-reinforced resin dowel and core for retention and reinforcement of the maxillary first premolar, and fabricating a definitive restoration using polyethylene fiber to reinforce the fixed partial denture.

  18. An investigation of the clinical experiences of dentists within the national dental foundation training programme in the North West of England.

    PubMed

    Palmer, N O A; Kirton, J A; Speechley, D

    2016-09-23

    Objective To investigate the clinical experiences of foundation dentists (FDs) in the North West of England.Methods Three research methods were used: a questionnaire completed by FDs at the end of their training; an analysis of the clinical logs of experience recorded in the educational portfolios; and analysis of NHS Business Services Authority (NHSBSA) activity data for the 12 month period of training of FDs.Results A response rate of 100% (N = 50) was achieved for the questionnaire and complete data for 49 of the 50 FDs was available from the NHSBSA and clinical logs in the educational portfolios.Discussion Trainees were satisfied with the clinical experience and believed their workload and patient mix provided a broad experience of clinical conditions, although 40% felt there were gaps in their clinical experience. There were wide ranges in the number of individual clinical procedures performed by FDs with some providing very few endodontic treatments, crowns, bridges, metal dentures and fissure sealants. There was a statistically significant difference (P <0.0005) in self- reporting of procedures recorded in the portfolio log when compared to the NHSBSA data.Conclusion The results from this study suggest that there is satisfaction amongst FDs with FT, but there is wide range in the level of clinical experience amongst FDs with some gaps which need to be addressed. In order to provide a consistent, cost effective approach to the delivery of FT changes are required to ensure minimum levels of clinical procedures are achieved during FT. The information collected in the training portfolio must be robust in order to make valid judgements on progress. PMID:27659636

  19. Courting the Rockefeller Foundation and other attempts to integrate clinical teaching, medical practice, and research in Melbourne.

    PubMed

    Westmore, Ann; Penington, David

    2009-01-01

    Courtesy of the cashed-up Rockefeller Foundation (RF), opportunity knocked in the 1920s for university medical schools committed to closer integration with teaching hospitals. The University of Melbourne Medical School, recognising the opportunity to win RF funds to help with rebuilding, sought government support for an audacious plan consistent with the university-hospital-research triads designed to advance medical science, that had strong RF support. Using a range of local archival sources, this paper details the back story to the development of the plan in the mid-1920s and its presentation to the RF by a high-powered delegation from Victoria in 1927. Although a change of government undermined the attempt and the RF money went to Sydney, sufficient momentum survived to implement the plan in several forms over the following decades, contributing to Victoria's subsequent leadership role in medical science. PMID:20481117

  20. Developing Outcomes Assessments as Endpoints for Registrational Clinical Trials of Antibacterial Drugs: 2015 Update From the Biomarkers Consortium of the Foundation for the National Institutes of Health.

    PubMed

    Talbot, George H; Powers, John H; Hoffmann, Steven C

    2016-03-01

    One important component in determining the benefits and harms of medical interventions is the use of well-defined and reliable outcome assessments as endpoints in clinical trials. Improving endpoints can better define patient benefits, allowing more accurate assessment of drug efficacy and more informed benefit-vs-risk decisions; another potential plus is facilitating efficient trial design. Since our first report in 2012, 2 Foundation for the National Institutes of Health Biomarkers Consortium Project Teams have continued to develop outcome assessments for potential uses as endpoints in registrational clinical trials of community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections. In addition, the teams have initiated similar work in the indications of hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia. This report provides an update on progress to date in these 4 diseases.

  1. GFR decline as an end point for clinical trials in CKD: a scientific workshop sponsored by the National Kidney Foundation and the US Food and Drug Administration.

    PubMed

    Levey, Andrew S; Inker, Lesley A; Matsushita, Kunihiro; Greene, Tom; Willis, Kerry; Lewis, Edmund; de Zeeuw, Dick; Cheung, Alfred K; Coresh, Josef

    2014-12-01

    The US Food and Drug Administration currently accepts halving of glomerular filtration rate (GFR), assessed as doubling of serum creatinine level, as a surrogate end point for the development of kidney failure in clinical trials of kidney disease progression. A doubling of serum creatinine level generally is a late event in chronic kidney disease (CKD); thus, there is great interest in considering alternative end points for clinical trials to shorten their duration, reduce sample size, and extend their conduct to patients with earlier stages of CKD. However, the relationship between lesser declines in GFR and the subsequent development of kidney failure has not been well characterized. The National Kidney Foundation and Food and Drug Administration sponsored a scientific workshop to critically examine available data to determine whether alternative GFR-based end points have sufficiently strong relationships with important clinical outcomes of CKD to be used in clinical trials. Based on a series of meta-analyses of cohorts and clinical trials and simulations of trial designs and analytic methods, the workshop concluded that a confirmed decline in estimated GFR of 30% over 2 to 3 years may be an acceptable surrogate end point in some circumstances, but the pattern of treatment effects on GFR must be examined, specifically acute effects on estimated GFR. An estimated GFR decline of 40% may be more broadly acceptable than a 30% decline across a wider range of baseline GFRs and patterns of treatment effects on GFR. However, there are other circumstances in which these end points could lead to a reduction in statistical power or erroneous conclusions regarding benefits or harms of interventions. We encourage careful consideration of these alternative end points in the design of future clinical trials.

  2. Subtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report

    PubMed Central

    Åkesson, K.; Bouxsein, M.; Kanis, J. A.; Napoli, N.; Papapoulos, S.; Reginster, J.-Y.; Cooper, C.

    2010-01-01

    Summary This paper reviews the evidence for an association between atypical subtrochanteric fractures and long-term bisphosphonate use. Clinical case reports/reviews and case–control studies report this association, but retrospective phase III trial analyses show no increased risk. Bisphosphonate use may be associated with atypical subtrochanteric fractures, but the case is yet unproven. Introduction A Working Group of the European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis and the International Osteoporosis Foundation has reviewed the evidence for a causal association between subtrochanteric fractures and long-term treatment with bisphosphonates, with the aim of identifying areas for further research and providing recommendations for physicians. Methods A PubMed search of literature from 1994 to May 2010 was performed using key search terms, and articles pertinent to subtrochanteric fractures following bisphosphonate use were analysed. Results Several clinical case reports and case reviews report a possible association between atypical fractures at the subtrochanteric region of the femur in bisphosphonate-treated patients. Common features of these ‘atypical’ fractures include prodromal pain, occurrence with minimal/no trauma, a thickened diaphyseal cortex and transverse fracture pattern. Some small case–control studies report the same association, but a large register-based study and retrospective analyses of phase III trials of bisphosphonates do not show an increased risk of subtrochanteric fractures with bisphosphonate use. The number of atypical subtrochanteric fractures in association with bisphosphonates is an estimated one per 1,000 per year. It is recommended that physicians remain vigilant in assessing their patients treated with bisphosphonates for the treatment or prevention of osteoporosis and advise patients of the potential risks. Conclusions Bisphosphonate use may be associated with atypical subtrochanteric

  3. Nemours Foundation

    MedlinePlus

    Children's Health Care I Want To: Find a Doctor View Insurance Accepted Pay My Bill Find Clinical Trials ... Volunteer View All Giving Back to top Your child. Our ... About Nemours Nemours is a nonprofit pediatric health system that provides life-changing medical care and ...

  4. BrightFocus Foundation

    MedlinePlus

    ... Alzheimer’s Disease Research Program Macular Degeneration Research Program National Glaucoma Research Program Molecular Neurodegeneration ... Foundation BrightFocus Foundation 22512 Gateway Center Drive Clarksburg, MD ...

  5. Proteus Syndrome Foundation

    MedlinePlus

    ... Criteria & FAQs Medical Research Glossary Donate Cash Donation Life Insurance Gift Matching Gift Stock Gift Sunshine Society Contact Privacy Policy Proteus Syndrome Foundation The Proteus Syndrome Foundation , a ...

  6. Mathematical foundations of biomechanics.

    PubMed

    Niederer, Peter F

    2010-01-01

    The aim of biomechanics is the analysis of the structure and function of humans, animals, and plants by means of the methods of mechanics. Its foundations are in particular embedded in mathematics, physics, and informatics. Due to the inherent multidisciplinary character deriving from its aim, biomechanics has numerous connections and overlapping areas with biology, biochemistry, physiology, and pathophysiology, along with clinical medicine, so its range is enormously wide. This treatise is mainly meant to serve as an introduction and overview for readers and students who intend to acquire a basic understanding of the mathematical principles and mechanics that constitute the foundation of biomechanics; accordingly, its contents are limited to basic theoretical principles of general validity and long-range significance. Selected examples are included that are representative for the problems treated in biomechanics. Although ultimate mathematical generality is not in the foreground, an attempt is made to derive the theory from basic principles. A concise and systematic formulation is thereby intended with the aim that the reader is provided with a working knowledge. It is assumed that he or she is familiar with the principles of calculus, vector analysis, and linear algebra. PMID:21303323

  7. The foundation of physicianship.

    PubMed

    Fuks, Abraham; Brawer, James; Boudreau, J Donald

    2012-01-01

    Although the practice of medicine continually changes in response to new biomedical understanding, novel technologies, and evolving cultural contexts, the ethical foundations of the clinical relationship between patient and physician paradoxically remain constant. There are fundamental characteristics with respect to character, behavior, and responsibilities that are descriptive of and necessary to the role of healer and that underpin the notion of physicianship. This article discusses the underlying characteristics or virtues that are necessary to the practice of medicine from the perspectives of three different philosophic traditions: the Aristotelian idea of phronesis as developed in the work of Edmund Pellegrino; the notion of alterity as framed by Emmanuel Levinas; and the attributes necessary to healing as laid out in the kabbala.

  8. Children's Tumor Foundation

    MedlinePlus

    ... The Children’s Tumor Foundation and Vice President Biden’s National Cancer Moonshot Initiative Oct 26, 2016, Posted in Collaborations , Latest News , Press Release , Science Foundation President Annette Bakker Participates in Key Meetings Dedicated ...

  9. Pediatric Brain Tumor Foundation

    MedlinePlus

    ... you insights into your child's treatment. LEARN MORE Brain tumors and their treatment can be deadly so ... Cancer Foundation joins the PBTF Read more >> Pediatric Brain Tumor Foundation 302 Ridgefield Court, Asheville, NC 28806 ...

  10. Restless Legs Syndrome Foundation

    MedlinePlus

    ... Syndrome Foundation is a registered 501(c)3 non-profit corporation (Tax ID #56-1784846). Donations are tax- ... Syndrome Foundation is a registered 501(c)3 non-profit corporation (Tax ID #56-1784846). Donations are tax- ...

  11. Oral Cancer Foundation

    MedlinePlus

    ... Famous People Famous historical Arts & Entertainment Sports figures ... The Oral Cancer Foundation The Oral Cancer Foundation is a national public service, non-profit entity designed to reduce suffering ...

  12. Kessler Foundation Research Center

    MedlinePlus

    ... Mindfulness-based Therapy in Children and Adolescents with Brain Injury Dr. Zanca of Kessler Foundation Receives $600,000 ... to Improve Learning among Children and Adolescents with Brain Injury Kessler Foundation Seeks Children and Adolescents for Brain ...

  13. Parkinson's Disease Foundation Newsletter

    MedlinePlus

    ... Newsletters These include monthly e-newsletters and quarterly science-specific e-newsletters. Read the latest issue below or browse the archives. National Parkinson Foundation and the Parkinson’s Disease Foundation Complete Merger to ...

  14. NCI collaborates with Multiple Myeloma Research Foundation

    Cancer.gov

    The National Cancer Institute (NCI) announced a collaboration with the Multiple Myeloma Research Foundation (MMRF) to incorporate MMRF's wealth of genomic and clinical data on the disease into the NCI Genomic Data Commons (GDC), a publicly available datab

  15. [The "Hersbruck Model". Application and integration of the DIN EN ISO 9001 quality norms with criteria of the European Foundation for Quality Management in a clinic].

    PubMed

    Fritze, B; Amon, U

    1999-11-01

    The german health system has dramatically changed and still continues to do so. Modified aspects concerning economy, customer orientation, competition, quality assurance and quality management seem to be increasingly important. Appropriate response to this challenge demands a relevant adjustment of a quality "philosophy" within a hospital. The "Hersbruck Model" has proven to be a suitable approach: on the basis of a quality management system--established and certified according to DIN EN ISO 9001--it implements all components of the model of the European Foundation for Quality Management. The modern quality tools as Total Quality Management and continuous quality improvement allow a permanent increase of customer/patient satisfaction.

  16. American Macular Degeneration Foundation

    MedlinePlus

    ... to content Contact DONATE Search for: Search Saving sight through research and education American Macular Degeneration Foundation Saving Sight Through Research and Education Menu About Macular Degeneration ...

  17. Foundation Design Handbook

    SciTech Connect

    Carmody, John; Mosiman, Garrett; Handeen, Daniel; Huelman, Patrick; Christian, Jeffery

    2013-10-01

    The purpose of this handbook is to provide information that will enable designers, builders, and homeowners to understand foundation design problems and solutions. The foundation of a house is a somewhat invisible and sometimes ignored component of the building. It is increasingly evident, however, that attention to good foundation design and construction has significant benefits to the homeowner and the builder, and can avoid some serious future problems. Good foundation design and construction practice means not only insulating to save energy, but also providing effective structural design as well as moisture, termite, and radon control techniques where appropriate.

  18. Osteogenesis Imperfecta Foundation

    MedlinePlus

    ... Foundation provides medically verified information to families and healthcare professionals, funds new OI research and promotes public policy that supports people living with osteogenesis imperfecta. Learn ...

  19. Foundations for Critical Thinking

    ERIC Educational Resources Information Center

    Bers, Trudy; Chun, Marc; Daly, William T.; Harrington, Christine; Tobolowsky, Barbara F.

    2015-01-01

    "Foundations for Critical Thinking" explores the landscape of critical-thinking skill development and pedagogy through foundational chapters and institutional case studies involving a range of students in diverse settings. By establishing a link between active learning and improved critical thinking, this resource encourages all higher…

  20. Foundation Development Abstracts, 1991.

    ERIC Educational Resources Information Center

    Anderson, James M., Ed.

    1991-01-01

    This series of brief two-page essays is published quarterly by the Network of California Community College Foundations to address topics related to development activities typically conducted by educational foundations. Volume 1 includes "Your Message is as Clear as Your Mission Statement," by Pat Rasmussen and James M. Anderson, which suggests…

  1. The Foundation Programme in psychiatry: a qualitative study into the effects of a foundation placement

    PubMed Central

    Boyle, Ann; Davies, Sophie; Dogra, Nisha; Perry, Jennifer; Fosker, Hannah

    2016-01-01

    Aims and method There is a drive to increase the number of psychiatry foundation placements to ensure that training keeps up with the changing health and social care landscape. This qualitative study aimed to explore, by interview, the experiences of 17 doctors who have completed a foundation placement in psychiatry. Results The study highlights the benefits of foundation psychiatry placements and some of their positive and negative aspects. Clinical implications Those developing foundation placements will need to ensure they are of high quality. PMID:27752349

  2. Builder's foundation handbook

    SciTech Connect

    Carmody, J. . Underground Space Center); Christian, J. ); Labs, K. )

    1991-05-01

    This handbook contains a worksheet for selecting insulation levels based on specific building construction, climate, HVAC equipment, insulation cost, and other economic considerations. The worksheet permits optimization of foundation insulation levels for new or retrofit applications. Construction details representing good practices for the design and installation of energy efficient basement, crawl space, and slab-n-grade foundations are the focal point of the handbook. The construction details are keyed to lists of critical design information useful for specifying structural integrity; thermal and vapor control; subsurface drainage; waterproofing; and mold, mildew, odor, decay, termite, and radon control strategies. Another useful feature are checklist chapter summaries covering major design considerations for each foundation type--basement, crawl space, and slab-on-grade. These checklist summaries are useful during design and construction inspection. The information in this handbook is drawn heavily from the first foundation handbook from the DOE/ORNL Building Envelope Systems and Materials Program, the Building Foundation Design Handbook (Labs et al., 1988), which is an extensive technical reference manual. This book presents what to do in foundation design'' in an inviting, concise format. This handbook is intended to serve the needs of active home builders; however, the information is pertinent to anyone involved in foundation design and construction decisions including homeowners, architects, and engineers. 17 refs., 49 figs., 18 tabs.

  3. Cleft Palate Foundation

    MedlinePlus

    ... Spanish , and Mandarin ! Information on Cleft Lip and Palate Our booklets and factsheets address a variety of ... Bear. –Paige with her Cleftline™ teddy bear– Cleft Palate Foundation 1504 East Franklin Street, Suite 102 Chapel ...

  4. Prostate Cancer Foundation

    MedlinePlus

    ... Close About Us Our Story A Legacy of Leadership About the Prostate Cancer Foundation CEO Message Why ... Cancer Board of Directors Annual Report & Financials Our Leadership Leadership Team A Legacy of Leadership Featured Take ...

  5. Children's Brain Tumor Foundation

    MedlinePlus

    ... CBTF Justin's Hope Fund Grant Recipients Grants Children’s Brain Tumor Foundation, A non-profit organization, was founded ... and the long term outlook for children with brain and spinal cord tumors through research, support, education, ...

  6. Oral Cancer Foundation

    MedlinePlus

    ... Oral Cancer Foundation is a national public service, non-profit entity designed to reduce suffering and save lives ... National Academy of Sciences (NAS) is a private, non-profit society of distinguished scholars. Established by an Act ...

  7. Scleroderma Research Foundation

    MedlinePlus

    ... Research Foundation in your estate planning guarantees your lifetime commitment to finding a cure will continue. Learn more The SRF: A Four Star Charity The SRF has achieved the highest possible ...

  8. National Fragile X Foundation

    MedlinePlus

    ... Anthology Advocacy National Fragile X Foundation Advocacy Day STAR: Local Advocacy Agenda and Accomplishments Community Events International ... Feeding and Fragile X Toilet Training the Older Child Oppositional or Merely Anxious? Public or Private? Managing ...

  9. Pulmonary Fibrosis Foundation

    MedlinePlus

    ... Belts! For PFF Spend an evening with the stars on Monday, February 27, 2017. MORE PFF Moved ... Patients The Pulmonary Fibrosis Foundation has a four-star rating from Charity Navigator and is a Better ...

  10. American Lyme Disease Foundation

    MedlinePlus

    ... Infectious Diseases, 35: 451-464, 2002) What is Lyme Disease? Lyme disease (LD) is an infection caused by ... mission with your own tax-deductible contribution. American Lyme Disease Foundation, Inc. PO Box 466 Lyme, CT 06371 ...

  11. A Foundation for Research

    ERIC Educational Resources Information Center

    Fowler, William A.

    1975-01-01

    Discusses the funding of scientific research by the National Science Foundation (NSF) during the past 25 years. Reviews in general terms the types of broad research accomplished through NSF funds in various fields of science. (MLH)

  12. National Hydrocephalus Foundation

    MedlinePlus

    ... with Hydrocephalus Fetal MRI Advancements Normal Pressure Hydrocephalus Communication and Development Therapy Eye Findings in Hydrocephalus News & Events Member Benefits & Services How to Join Make a Donation Website design by SDGi . © 2014 National Hydrocephalus Foundation. All rights ...

  13. National Pancreas Foundation

    MedlinePlus

    ... to NPF Contact Us Newsletter Sign Up Social Networking Button – Medium Search: Main menu Skip to primary ... 20814 1.866.726.2737 | Contact Us Social Networking Button – Medium © 2014 The National Pancreas Foundation | Health ...

  14. National Ataxia Foundation

    MedlinePlus

    ... Minnesota Walk, Stroll n’ Roll St. Louis Park, MN September 10 New England Walk n’ Roll Bristol, ... Ataxia Foundation • 2600 Fernbrook Lane Suite 119 • Minneapolis, MN 55447 • 763.553.0020 naf@ataxia.org | Site ...

  15. National Reye's Syndrome Foundation

    MedlinePlus

    ... Packages - Free! Talking to Tweens and Teens About Aspirin and Other Medications Join the Effort to Eradicate ... Foundation's LinkedIn profile Spread Awareness with the Kids & Aspirin Don't Mix car magnet ribbon. Get News & ...

  16. United Leukodystrophy Foundation

    MedlinePlus

    ... Benefit Drawing to … Read More » Research Grant Applications Now Being Solicited The United Leukodystrophy Foundation is soliciting grant applications to support … Read More » Dr. Matalon Wins ULF Service Award Congratulations to Dr. Reuben Matalon ...

  17. Laboratory survey and literature review of anaerobic bacteriology: foundations of a clinically orientated and evidence-based workup for anaerobic cultures.

    PubMed

    Peeters, Bart; Magerman, Koen; Waumans, Luc; Cartuyvels, Reinoud

    2016-09-01

    Since the introduction of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) in routine microbiology laboratories, identification of anaerobic bacteria has become easier. These increased possibilities provide new challenges concerning analytical workup and reporting of anaerobes. In February 2015, an extensive web-based survey on pre-analytical, analytical and post-analytical procedures of anaerobic microbiology was sent to 53 Belgian, university and non-university hospital laboratories. Answers of 34 participating laboratories revealed a huge diversity in all analytical stages of anaerobic microbiology. Whether or not colony types were identified was mainly based on anatomical origin of the sample, colony morphology, and total number of different anaerobic isolates in the sample, while reporting of isolate results and performing anti-microbial susceptibility testing was mainly based on anatomical origin of the sample, number of different anaerobic isolates, and the identification of the anaerobic bacteria. These variety of workup procedures were mainly expert-based and have not been extensively clinically validated. For this reason, a standardized, clinically orientated, and feasible procedure for the workup of anaerobic cultures was developed, using MALDI-TOF MS identification, based upon literature data and existing guidelines.

  18. Laboratory survey and literature review of anaerobic bacteriology: foundations of a clinically orientated and evidence-based workup for anaerobic cultures.

    PubMed

    Peeters, Bart; Magerman, Koen; Waumans, Luc; Cartuyvels, Reinoud

    2016-09-01

    Since the introduction of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) in routine microbiology laboratories, identification of anaerobic bacteria has become easier. These increased possibilities provide new challenges concerning analytical workup and reporting of anaerobes. In February 2015, an extensive web-based survey on pre-analytical, analytical and post-analytical procedures of anaerobic microbiology was sent to 53 Belgian, university and non-university hospital laboratories. Answers of 34 participating laboratories revealed a huge diversity in all analytical stages of anaerobic microbiology. Whether or not colony types were identified was mainly based on anatomical origin of the sample, colony morphology, and total number of different anaerobic isolates in the sample, while reporting of isolate results and performing anti-microbial susceptibility testing was mainly based on anatomical origin of the sample, number of different anaerobic isolates, and the identification of the anaerobic bacteria. These variety of workup procedures were mainly expert-based and have not been extensively clinically validated. For this reason, a standardized, clinically orientated, and feasible procedure for the workup of anaerobic cultures was developed, using MALDI-TOF MS identification, based upon literature data and existing guidelines. PMID:27344540

  19. Clinical forensic medicine and its main fields of activity from the foundation of the German Society of Legal Medicine until today.

    PubMed

    Pollak, S

    2004-09-10

    The fields mainly covered by clinical forensic medicine are subject to time-related changes which are described on the basis of the German literature of the 20th century. Some fields of forensic sexual medicine (diagnosis of virginity, proof of criminal abortion, potentia coeundi, potentia generandi, potentia concipiendi) have become less important in the daily work of medicolegal institutes, whereas victims of rape and sexual abuse continue to form a major part of the forensic examination material in the German-speaking countries. The evaluation of suspected physical child abuse has grown in importance since the 60s, and it is essentially the merit of Elisabeth Trube-Becker that this problem is now dealt with also in scientific medicine. More recently, medicolegal experts are increasingly confronted with further groups of persons: victims of domestic violence, abused/neglected seniors, refugees from countries where torture is used. A new special field, which established itself only in the 90s, is the estimation of age with regard to the criminal responsibility of suspects who have no identity papers or pretend to have none. A phenomenon frequently observed in the last two decades is the non-accidental self-infliction of injuries. Whereas in the first half of the 20th century the motive for self-mutilation was typically to evade military service, this category of injury was later mainly seen in the context of insurance fraud; more recently most forensically relevant self-inflicted injuries refer to simulated offenses (fictitious sexual offenses and robbery, attacks allegedly having a political background). One of the traditional fields of clinical forensic medicine continues to be the evaluation of victims and suspects following bodily harm and attempted homicides. In the field of civil law medicolegal experts are particularly often concerned with controversial consequences of traffic accidents (e.g. alleged whiplash injuries after rear-end collisions at low

  20. Clinical forensic medicine and its main fields of activity from the foundation of the German Society of Legal Medicine until today.

    PubMed

    Pollak, S

    2004-09-10

    The fields mainly covered by clinical forensic medicine are subject to time-related changes which are described on the basis of the German literature of the 20th century. Some fields of forensic sexual medicine (diagnosis of virginity, proof of criminal abortion, potentia coeundi, potentia generandi, potentia concipiendi) have become less important in the daily work of medicolegal institutes, whereas victims of rape and sexual abuse continue to form a major part of the forensic examination material in the German-speaking countries. The evaluation of suspected physical child abuse has grown in importance since the 60s, and it is essentially the merit of Elisabeth Trube-Becker that this problem is now dealt with also in scientific medicine. More recently, medicolegal experts are increasingly confronted with further groups of persons: victims of domestic violence, abused/neglected seniors, refugees from countries where torture is used. A new special field, which established itself only in the 90s, is the estimation of age with regard to the criminal responsibility of suspects who have no identity papers or pretend to have none. A phenomenon frequently observed in the last two decades is the non-accidental self-infliction of injuries. Whereas in the first half of the 20th century the motive for self-mutilation was typically to evade military service, this category of injury was later mainly seen in the context of insurance fraud; more recently most forensically relevant self-inflicted injuries refer to simulated offenses (fictitious sexual offenses and robbery, attacks allegedly having a political background). One of the traditional fields of clinical forensic medicine continues to be the evaluation of victims and suspects following bodily harm and attempted homicides. In the field of civil law medicolegal experts are particularly often concerned with controversial consequences of traffic accidents (e.g. alleged whiplash injuries after rear-end collisions at low

  1. Thermodynamics: Frontiers and Foundations.

    SciTech Connect

    JEFFERY,; LEWINS, D.

    2009-07-27

    Version 00 Dr. J.D. Lewins has now released the following new book for free distribution: Thermodynamics: Frontiers and Foundations, Preface by Sir Alan Cottrell Introduction 1. Four-Square Foundations: The Laws of Thermodynamics 2. Maximum Entropy and Minimum Energy: The Master Functions and Equations 3. Ideal Gases and their Applications 4. Real Fluids and Some Applications 5. Van der Waals: A Model for Real Fluids 6. Surface Tension: Bubbles and Drops 7. Inert and Reactive Mixtures; An introduction to Chemical Thermodynamics 8. Radiation Thermodynamics: Solar Power Potential 9. Outposts of the Empire 10. A Glimpse into Statistical Thermodynamics Envoi

  2. Thermodynamics: Frontiers and Foundations.

    2009-07-27

    Version 00 Dr. J.D. Lewins has now released the following new book for free distribution: Thermodynamics: Frontiers and Foundations, Preface by Sir Alan Cottrell Introduction 1. Four-Square Foundations: The Laws of Thermodynamics 2. Maximum Entropy and Minimum Energy: The Master Functions and Equations 3. Ideal Gases and their Applications 4. Real Fluids and Some Applications 5. Van der Waals: A Model for Real Fluids 6. Surface Tension: Bubbles and Drops 7. Inert and Reactive Mixtures;more » An introduction to Chemical Thermodynamics 8. Radiation Thermodynamics: Solar Power Potential 9. Outposts of the Empire 10. A Glimpse into Statistical Thermodynamics Envoi« less

  3. The Foundation Directory, Edition 4.

    ERIC Educational Resources Information Center

    Lewis, Marianna O., Ed.; Bowers, Patricia, Ed.

    The fourth edition of "The Foundation Directory" lists and describes 5,454 foundations and surveys their grants. The directory was prepared from foundation reports and government records. The foundations listed either have assets of $500.00 or made grants totally at least $25,000.00 in the year of record. Education is the leading beneficiary of…

  4. Cultivating Foundation Support for Education.

    ERIC Educational Resources Information Center

    Murphy, Mary Kay, Ed.

    The process of acquiring financial support from private foundations is discussed in 26 essays, divided into five categories (Targeting the Foundation Market; Getting Started: Tools of the Trade; The Process of Foundation Fund Raising; The Grant Maker's Perspective; and Focused Programs and Foundation Support). A prologue, "Ethics and Foundation…

  5. The Broad Foundations, 2008

    ERIC Educational Resources Information Center

    Broad Foundation, 2008

    2008-01-01

    This 2008 foundation report provides an opportunity to look back and ahead as the organization reviews what has been accomplished and identifies challenges to be tackled in the future in the areas of education, scientific and medical research, and the arts. Grant making from the perspective of grantees is presented in each area. [This document was…

  6. Foundation for the Future.

    ERIC Educational Resources Information Center

    National Science Foundation, Washington, DC. Directorate for Education and Human Resources.

    This document describes some of the many programs sponsored by the National Science Foundation in its efforts to continue to promote systemic science and mathematics education reform. Brief descriptions of the following programs are included: (1) Interactive Math Program Restructures 9-12 Math Education; (2) Algebra I Project Sparks Citywide…

  7. The Broad Foundations, 2006

    ERIC Educational Resources Information Center

    Broad Foundation, 2006

    2006-01-01

    The mission of the Broad Foundations is to transform K-12 urban public education through better governance, management, labor relations and competition; make significant contributions to advance major scientific and medical research; foster public appreciation of contemporary art by increasing access for audiences worldwide; and lead and…

  8. Immune Deficiency Foundation

    MedlinePlus

    ... for IDF Join our nationwide network of volunteers Resources For Patients & Families Peer Support Speak with someone who understands Locate a Physician ... secure Legacy Giving Establish your personal legacy and support IDF 'Immune Deficiency Foundation Remembers' Plaque Pay tribute to ... Educational Resources Find a wealth of IDF educational publications and ...

  9. Parkinson's Disease Foundation

    MedlinePlus

    ... PDF®), a division of the Parkinson's Foundation, seeks research proposals for emerging ideas to help solve, treat and end the disease. PDF investments of $2.7 million are part of its comprehensive strategy to mobilize ... Initiatives Research We Fund Results Apply ...

  10. Foundations of Distance Education.

    ERIC Educational Resources Information Center

    Morabito, Margaret Gorts

    The foundations, development, and delivery of distance education were examined through a literature review and first-hand experience in administration and teaching in an international online school. The evolution of distance education was traced from the 1800s, when it was a print-based method of instruction conducted at a distance, through the…

  11. Foundations of logic programming

    SciTech Connect

    Lloyd, J.W.

    1987-01-01

    This is the second edition of the first book to give an account of the mathematical foundations of Logic Programming. Its purpose is to collect the basic theoretical results of Logic Programming, which have previously only been available in widely scattered research papers. In addition to presenting the technical results, the book also contains many illustrative examples. Many of the examples and problems are part of the folklore of Logic Programming and are not easily obtainable elsewhere.

  12. CONVEYOR FOUNDATIONS CALCULATION

    SciTech Connect

    S. Romanos

    1995-03-10

    The purpose of these calculations is to design foundations for all conveyor supports for the surface conveyors that transport the muck resulting from the TBM operation, from the belt storage to the muck stockpile. These conveyors consist of: (1) Conveyor W-TO3, from the belt storage, at the starter tunnel, to the transfer tower. (2) Conveyor W-SO1, from the transfer tower to the material stacker, at the muck stockpile.

  13. Wronski's Foundations of Mathematics.

    PubMed

    Wagner, Roi

    2016-09-01

    Argument This paper reconstructs Wronski's philosophical foundations of mathematics. It uses his critique of Lagrange's algebraic analysis as a vignette to introduce the problems that he raised, and argues that these problems have not been properly appreciated by his contemporaries and subsequent commentators. The paper goes on to reconstruct Wronski's mathematical law of creation and his notions of theory and techne, in order to put his objections to Lagrange in their philosophical context. Finally, Wronski's proof of his universal law (the expansion of a given function by any series of functions) is reviewed in terms of the above reconstruction. I argue that Wronski's philosophical approach poses an alternative to the views of his contemporary mainstream mathematicians, which brings up the contingency of their choices, and bridges the foundational concerns of early modernity with those of the twentieth-century foundations crisis. I also argue that Wronski's views may be useful to contemporary philosophy of mathematical practice, if they are read against their metaphysical grain. PMID:27573997

  14. Physicians and foundation hospitals.

    PubMed

    Cooper, John; Black, Carol

    2003-01-01

    Foundation NHS Trusts will be constituted in the same way as Mutual Societies, and local people and patients will be invited to become subscribers. Subscribers will elect a board of governors who will appoint the non-executive directors of the Trusts. Foundation Trusts will be outside the performance management system, but will be subject to a regulator and to inspection. Contracts with commissioners will be legally enforceable. Issues discussed in the article include: financial borrowing; whether competition is being reintroduced; poaching staff; fears of a two-tier health service; fragmentation of the NHS; the impact on research and teaching; and the impact on the current 'target culture'. Local communities and patient groups may welcome involvement with their local hospitals, but special interest groups could be a danger. Foundation Trusts may bring back some of the better features of NHS Trusts as originally conceived, and offer better opportunities for clinicians to influence local policies and priorities. Fears of yet another organisational change are an important issue. Only time will tell whether the outcome will justify the effort the changes will involve. PMID:14703035

  15. Wronski's Foundations of Mathematics.

    PubMed

    Wagner, Roi

    2016-09-01

    Argument This paper reconstructs Wronski's philosophical foundations of mathematics. It uses his critique of Lagrange's algebraic analysis as a vignette to introduce the problems that he raised, and argues that these problems have not been properly appreciated by his contemporaries and subsequent commentators. The paper goes on to reconstruct Wronski's mathematical law of creation and his notions of theory and techne, in order to put his objections to Lagrange in their philosophical context. Finally, Wronski's proof of his universal law (the expansion of a given function by any series of functions) is reviewed in terms of the above reconstruction. I argue that Wronski's philosophical approach poses an alternative to the views of his contemporary mainstream mathematicians, which brings up the contingency of their choices, and bridges the foundational concerns of early modernity with those of the twentieth-century foundations crisis. I also argue that Wronski's views may be useful to contemporary philosophy of mathematical practice, if they are read against their metaphysical grain.

  16. Foundations of chaotic mixing.

    PubMed

    Wiggins, Stephen; Ottino, Julio M

    2004-05-15

    The simplest mixing problem corresponds to the mixing of a fluid with itself; this case provides a foundation on which the subject rests. The objective here is to study mixing independently of the mechanisms used to create the motion and review elements of theory focusing mostly on mathematical foundations and minimal models. The flows under consideration will be of two types: two-dimensional (2D) 'blinking flows', or three-dimensional (3D) duct flows. Given that mixing in continuous 3D duct flows depends critically on cross-sectional mixing, and that many microfluidic applications involve continuous flows, we focus on the essential aspects of mixing in 2D flows, as they provide a foundation from which to base our understanding of more complex cases. The baker's transformation is taken as the centrepiece for describing the dynamical systems framework. In particular, a hierarchy of characterizations of mixing exist, Bernoulli --> mixing --> ergodic, ordered according to the quality of mixing (the strongest first). Most importantly for the design process, we show how the so-called linked twist maps function as a minimal picture of mixing, provide a mathematical structure for understanding the type of 2D flows that arise in many micromixers already built, and give conditions guaranteeing the best quality mixing. Extensions of these concepts lead to first-principle-based designs without resorting to lengthy computations.

  17. Oxalosis and Hyperoxaluria Foundation

    MedlinePlus

    ... Menu Home Learn Learn Symptoms Diagnosis Treatment Dialysis Organ Donation & Transplants Research Clinical Trials Grants & Funding Patient Registry ... 8699 Home Learn Learn Symptoms Diagnosis Treatment Dialysis Organ Donation & Transplants Research Clinical Trials Grants & Funding Patient Registry ...

  18. Cardiovascular Research Foundation

    MedlinePlus

    ... stents Clinicians and Industry Innovate Skirball Center for Innovation Investigate Clinical Trials Center Educate Center for Education ... stents Clinicians and Industry Innovate Skirball Center for Innovation Investigate Clinical Trials Center Educate Center for Education ...

  19. Queensland Emergency Medicine Research Foundation: special report.

    PubMed

    FitzGerald, Gerry; Codd, Catrina; Aitken, Peter; Sinnott, Michael

    2012-02-01

    Development of any new profession is dependent on the development of a special body of knowledge that is the domain of the profession. Key to this is research. Following sustained lobbying, the Queensland Government agreed to establish an emergency medicine research fund as part of an Enterprise Bargaining Agreement in 2006. That fund is managed by the Queensland Emergency Medicine Research Foundation. The present article describes the strategic approaches of the Foundation in its first 3 years, the application of research funds, and foreshadows an evaluative framework for determining the strategic value of this investment. The Foundation has developed a range of personnel and project support funding programmes, and competition for funding has increased. Ongoing evaluation will seek to determine the effectiveness of the current funding strategy on improving the effectiveness of research performance. It will also evaluate the clinical and organizational outcomes.

  20. Farm Foundation Annual Report, 2000.

    ERIC Educational Resources Information Center

    Farm Foundation, Oak Brook, IL.

    The Farm Foundation was established in 1933 as a private agency to help coordinate the work of other public and private groups and agencies to improve agriculture and rural life without taking political positions or supporting specific legislation. An operating rather than a grant-making foundation, the foundation develops national and regional…

  1. Students' Perceptions of Foundation Degrees

    ERIC Educational Resources Information Center

    Ooms, A.; Burke, L. M.; Marks-Maran, D. J.; Webb, M.; Cooper, D.

    2012-01-01

    In 2008 there were 87,339 people enrolled on foundation degrees (FDs) in the UK (Foundation Degree Forward, 2009), and educational institutions in the UK offered 1700 different foundation degrees in over 25 subjects, with nearly 900 more in development (Action on Access, 2010). In addition, student views are seen to be of importance, as…

  2. Foundations of Geomagnetism

    NASA Astrophysics Data System (ADS)

    Jackson, Andy

    The study of the magnetic field of the Earth, or geomagnetism, is one of the oldest lines of scientific enquiry. Indeed, it has often been said that William Gilbert's De Magnete, published in 1600 and predating Isaac Newton's Principia by 87 years, can claim to be the first true scientific textbook; his study was essentially the first of academic rather than practical interest.What then, we may ask, has been accomplished in the nearly 400 intervening years up to the publication of Foundations of Geomagnetism? In short, a wealth of observational evidence, considerable physical understanding, and a great deal of mathematical apparatus have accrued, placing the subject on a much surer footing.The latter two categories are described in considerable detail, and with attendant rigor, in this book. The sphericity of the Earth means that a frequent theme in the book is the solution of the partial differential equations of electrodynamics in a spherical geometry.

  3. National Headache Foundation

    MedlinePlus

    ... has been to further awareness of headache and migraine as legitimate neurobiological diseases. Much has changed during this time, and with aid from advanced technology and clinical innovation, there are more treatment options than ever before. However, we understand that ...

  4. Creating a Successful Affiliated Foundation. Foundation Relations. Board Basics.

    ERIC Educational Resources Information Center

    Hedgepeth, Royster C.

    1999-01-01

    This booklet for trustees of institutions of higher education offers guidelines for the creation of effective affiliated foundations. An introductory section notes the increased use of such foundations by public colleges and universities for institutional fund-raising and management of property and endowments. The booklet finds that successful…

  5. Foundations of resilience thinking.

    PubMed

    Curtin, Charles G; Parker, Jessica P

    2014-08-01

    Through 3 broad and interconnected streams of thought, resilience thinking has influenced the science of ecology and natural resource management by generating new multidisciplinary approaches to environmental problem solving. Resilience science, adaptive management (AM), and ecological policy design (EPD) contributed to an internationally unified paradigm built around the realization that change is inevitable and that science and management must approach the world with this assumption, rather than one of stability. Resilience thinking treats actions as experiments to be learned from, rather than intellectual propositions to be defended or mistakes to be ignored. It asks what is novel and innovative and strives to capture the overall behavior of a system, rather than seeking static, precise outcomes from discrete action steps. Understanding the foundations of resilience thinking is an important building block for developing more holistic and adaptive approaches to conservation. We conducted a comprehensive review of the history of resilience thinking because resilience thinking provides a working context upon which more effective, synergistic, and systems-based conservation action can be taken in light of rapid and unpredictable change. Together, resilience science, AM, and EPD bridge the gaps between systems analysis, ecology, and resource management to provide an interdisciplinary approach to solving wicked problems.

  6. Foundations of resilience thinking.

    PubMed

    Curtin, Charles G; Parker, Jessica P

    2014-08-01

    Through 3 broad and interconnected streams of thought, resilience thinking has influenced the science of ecology and natural resource management by generating new multidisciplinary approaches to environmental problem solving. Resilience science, adaptive management (AM), and ecological policy design (EPD) contributed to an internationally unified paradigm built around the realization that change is inevitable and that science and management must approach the world with this assumption, rather than one of stability. Resilience thinking treats actions as experiments to be learned from, rather than intellectual propositions to be defended or mistakes to be ignored. It asks what is novel and innovative and strives to capture the overall behavior of a system, rather than seeking static, precise outcomes from discrete action steps. Understanding the foundations of resilience thinking is an important building block for developing more holistic and adaptive approaches to conservation. We conducted a comprehensive review of the history of resilience thinking because resilience thinking provides a working context upon which more effective, synergistic, and systems-based conservation action can be taken in light of rapid and unpredictable change. Together, resilience science, AM, and EPD bridge the gaps between systems analysis, ecology, and resource management to provide an interdisciplinary approach to solving wicked problems. PMID:24975863

  7. Ford Foundation Fellowships

    NASA Astrophysics Data System (ADS)

    The Ford Foundation is sponsoring 40 three-year predoctoral fellowships and 10 one-year dissertation fellowships for minorities for 1987. The predoctoral fellowships include an annual stipend of $10,000 and an annual grant of $6000 to the fellow's institution in lieu of tuition and fees. Dissertation Fellows will receive a stipend of $18,000 and no institutional grant.The program is designed to increase the presence of under represented minorities in the nation's college and university faculties. The minority groups to be considered under this program are: American Indians, Alaskan Natives (Eskimo or Aleut), Black Americans, Mexican Americans/Chicanos, Native Pacific Islanders (Polynesians or Micronesians), and Puerto Ricans. The competition is open to any U.S. citizen who is a member of one of these groups, who is a beginning graduate student or is within 1 year of completing the dissertation, and who expects to work toward a Ph.D. or Sc.D. degree. Fellowships will be awarded in the behavioral and social sciences, humanities, engineering, mathematics, physical sciences, and biological sciences. The National Research Council, which is administering the fellowships, can provide more information on which fields of study are and are not eligible for this program.

  8. Dystonia Medical Research Foundation

    MedlinePlus

    ... in the U.S. alone. Join us in the global effort to find a cure. Learn More About Dystonia Dystonia news Addex Therapeutics to Conduct Clinical Study of Dipraglurant in Cervical Dystonia Local Leader Organizes First Cedar Rapids Dogs4Dystonia Dog Walk ...

  9. Foundations for Gerontological Education.

    ERIC Educational Resources Information Center

    Johnson, Harold R.; And Others

    1980-01-01

    Focuses on: (1) components of a basic core of knowledge essential for all people working in the field of aging; (2) knowledge essential for professions related to biomedical science, human services, social and physical environment; and (3) knowledge essential for clinical psychology, nursing, nutrition, and social work. (Author)

  10. Establishing a Local Education Foundation.

    ERIC Educational Resources Information Center

    Pressley, James S.; Markland, Maureen S.

    This paper describes the process of establishing local education foundations for the purpose of raising revenues to supplement, not supplant, existing school programs. Plans to identify funding sources and define the purpose of the foundation tied to student and academic achievement must emerge in order to solicit private individuals or groups,…

  11. Theoretical Foundations of Learning Environments

    ERIC Educational Resources Information Center

    Jonassen, David H., Ed.; Land, Susan M., Ed.

    1999-01-01

    "Theoretical Foundations of Learning Environments" describes the most contemporary psychological and pedagogical theories that are foundations for the conception and design of open-ended learning environments and new applications of educational technologies. In the past decade, the cognitive revolution of the 60s and 70s has been replaced or…

  12. Cornelia de Lange Syndrome Foundation

    MedlinePlus

    ... online suggestion box . Mailing Address: Cornelia de Lange Syndrome Foundation 302 West Main Street, #100 Avon, Connecticut 06001 USA What Is CdLS? Who We Are What We Do Research Get Involved Find Support ... & Terms Site Map The Cornelia de Lange Syndrome (CdLS) Foundation is a family support organization that ...

  13. Foundation Degrees: A Risky Business?

    ERIC Educational Resources Information Center

    Rowley, Jennifer

    2005-01-01

    Purpose: Foundation degrees, the new proposal for sub-degree vocational education in the UK, are characterised by innovation both in their design (curriculum, teaching, learning and assessment) and in the marketplace for which they are designed. This article argues that the development and delivery of foundation degrees carry a high level of risk,…

  14. The Psychological Foundations of Mathematics.

    ERIC Educational Resources Information Center

    Suppes, Patrick

    1967-01-01

    This paper outlines problems which are central to the psychological foundations of mathematics. Discussed are the relations that exist between psychological and classical foundations of mathematics. It is shown how the inadequacies of current learning theories which account for complex mathematics learning may be made explicit for appropriate…

  15. NEWS: Solid foundations?

    NASA Astrophysics Data System (ADS)

    2000-07-01

    Among the initiatives to be found at UK universities is a vocational award with the title `University Foundation Degree' at Nottingham Trent University. This qualification will be offered in 14 different subjects including four in the Faculty of Science and Mathematics, in the areas of applied biology, applied sciences, chemistry and physics. The courses will be available on a two-year full-time, three-year sandwich or a part-time basis. Set at a higher standard and specification than the Higher National Diplomas which it replaces, the UFD has been devised in consultation with industry and will cover the technical and specialist areas demanded by employers to combat skills shortages. The UFD in applied sciences concentrates on practical applications through laboratory, IT and project work, supported by lectures and seminars. At the end students can enter the employment market or transfer onto the second year of a degree course. Science-based careers including research and development would be the aim of those taking the UFD in physics. The first year develops the fundamentals of modern physics supported by studies in mathematics, IT and computer programming, whilst year 2 is vocational in nature with industrial problem solving and work experience as well as an academic theme associated with environmental aspects of the subject. Those who complete the UFD will be allowed automatic progression to a specified honours degree course and would normally be expected to study for a further two years for this award. However, those demonstrating an outstanding academic performance can transfer to the linked degree programme at the end of the first year via fast-track modules. Back in May the UK's Quality Assurance Agency (QAA) announced new standard benchmarks for degrees. These will be introduced into higher education institutions from 2002 to outline the knowledge, understanding and skills a student should gain from a particular higher education course. These benchmark

  16. Polish Foundation for Energy Efficiency

    SciTech Connect

    1995-12-31

    The Polish Foundation for Energy Efficiency (FEWE) was established in Poland at the end of 1990. FEWE, as an independent and non-profit organization, has the following objectives: to strive towards an energy efficient national economy, and to show the way and methods by use of which energy efficiency can be increased. The activity of the Foundation covers the entire territory of Poland through three regional centers: in Warsaw, Katowice and Cracow. FEWE employs well-known and experienced specialists within thermal and power engineering, civil engineering, economy and applied sciences. The organizer of the Foundation has been Battelle Memorial Institute - Pacific Northwest Laboratories from the USA.

  17. Willis-Ekbom Disease Foundation

    MedlinePlus

    ... specialist through the RLS Foundation website. After a sleep study, we learned that I have restless legs syndrome, just like my grandfather. With treatment I can sleep again. I avoid triggers and my grades are ...

  18. Crohn's & Colitis Foundation of America

    MedlinePlus

    ... enabled to enjoy the full interactive experience. Crohn's & Colitis Foundation of America Find a Doctor Find a ... Local Chapters News Events Search: What are Crohn's & Colitis? What is Crohn's Disease What is Ulcerative Colitis ...

  19. Foundation for Film and Science

    ERIC Educational Resources Information Center

    van der Veen, G.

    1976-01-01

    Provides a comprehensive discussion on the Stichting Film en Wetenschap, SFW (Foundation for Film and Science), in Utrecht. Various aspects of the use of audio-visual aids in university teaching are looked at in detail. (Editor/RK)

  20. Influence of wind turbine foundation

    NASA Technical Reports Server (NTRS)

    Yee, S. T.

    1978-01-01

    The 200 kW Mod-0A wind turbine was modeled using a 3 lumped mass-spring system for the superstructure and a rotational spring for the foundation and supporting soil. Natural frequencies were calculated using soil elastic moduli varying from 3000 to 22,400 p.s.i. The reduction in natural frequencies from the rigid foundation case ranged up to 20 percent.

  1. A behaviorological thanatology: Foundations and implications

    PubMed Central

    Fraley, Lawrence E.

    1998-01-01

    Foundation principles supporting a behaviorological thanatology are reviewed, including concepts of life, person, death, value, right, ethic, and body/person distinctions. These natural science foundations are contrasted with traditional foundations, and their respective implications are speculatively explored. PMID:22478293

  2. A behaviorological thanatology: Foundations and implications.

    PubMed

    Fraley, L E

    1998-01-01

    Foundation principles supporting a behaviorological thanatology are reviewed, including concepts of life, person, death, value, right, ethic, and body/person distinctions. These natural science foundations are contrasted with traditional foundations, and their respective implications are speculatively explored.

  3. Teaching fellowships for UK foundation doctors.

    PubMed

    Qureshi, Shaun

    2015-01-01

    Teaching Fellowships for junior doctors in their second post-graduate (FY2) year should be considered by medical students and junior doctors in UK. FY2 Teaching Fellowships are available in many foundation schools as part of the UK Academic Foundation Programme. Although programme structures differ between schools, they are designed to allow junior trainees to take time out from clinical practice to develop their teaching skills and gain insights into medication education careers. The advantages of an FY2 teaching fellowship include valuable experience of teaching and formal feedback not available to other trainees; the opportunity to further develop your portfolio; further development of the trainee's own knowledge and skills; the stimulation of working with students. Potential drawbacks to be considered are reduced direct clinical contact; reduced salary; difficulty carrying out education research in the allocated time frame; occasional difficulties establishing the teacher-student relationship while the trainee is at a relatively junior level. Experience of medical education as an FY2 trainee provides a helpful stepping stone whether or not the trainee further pursues education as a career, because the teaching skills are transferable to any specialty, and the unique experience enhances the trainee's confidence as a role model for junior colleagues.

  4. Foundation + Collaboration + Inspiration. The Joyce Foundation 2009 Annual Report

    ERIC Educational Resources Information Center

    Joyce Foundation, 2010

    2010-01-01

    Among the great strengths of a policy-oriented foundation like Joyce is the willingness to take a long view, to be patient investors in ideas that take time to have impact, and to take chances on projects that may not work out. But in times of crisis, Joyce team and partners also have an obligation to be responsive to immediate challenges in their…

  5. Pavlov and the Rockefeller Foundation.

    PubMed

    Windholz, G; Kuppers, J R

    1988-01-01

    Despite the tension between the United States and the Soviet Union in the early 1920's, the Rockefeller Foundation and the Rockefeller Institute for Medical Research found ways to assist I.P. Pavlov. In addition to providing scientific literature and financial aid, these institutions and their officers rendered important moral support to the scientific career of Pavlov during his later years. In 1923, as a guest of the Rockefeller Institute, Pavlov visited American scientific laboratories. In 1924, he requested and received a number of books on physiology, and during the 1930's the Foundation helped him to acquire equipment for his Leningrad laboratory.

  6. Raising Money Through an Institutionally Related Foundation.

    ERIC Educational Resources Information Center

    Reilley, Timothy A., Ed.

    The creation of foundations for fund raising at public colleges and new ideas and techniques for established foundations are discussed in 13 chapters. The relationship of the foundation and the institution is described from the viewpoint of the institution and also that of the foundation. Article titles and authors include: "How the Foundation…

  7. But…What about My Epistemological Foundations?

    ERIC Educational Resources Information Center

    Curin, Raquel Isabel Barrera

    2015-01-01

    At one time or another, all researchers in mathematics education must face the rather complex question of their epistemological foundations. Discussing epistemological foundations naturally leads to a conversation about theories. Theories and epistemological foundations work in a circular fashion: theories can have epistemological foundations and…

  8. Foundations of Responsibility for Children

    ERIC Educational Resources Information Center

    Dillen, Annemie

    2008-01-01

    Children's vulnerability asks for people taking up responsibility for children. In this contribution, three different ways of thinking on foundations of (ethical and spiritual) responsibility for children are discussed, namely, a liberalist, a social-constructivist and a naturalist paradigm. The author argues that cultural and natural elements are…

  9. Principles for Foundations of Education.

    ERIC Educational Resources Information Center

    Britt, John

    The significance of the foundations of education approach to teaching is apparent in the ideas of John Henry Newman, Karl Jaspers, Jose Ortega y Gasset, and Mortimer Adler. Newman maintained that there is a circle of knowledge and once this unity is ignored the result is distortion in the learners and in the knowledge. To retain the whole, the…

  10. Building Trades. Block II. Foundations.

    ERIC Educational Resources Information Center

    Texas A and M Univ., College Station. Vocational Instructional Services.

    Twelve informational lessons and eleven manipulative lessons are provided on foundations as applied to the building trades. Informational lessons cover land measurements; blueprint reading; level instruments; building and site planning; building site preparation; laying out building lines; soil preparation and special evacuation; concrete forms;…

  11. Soils and Foundations: A Syllabus.

    ERIC Educational Resources Information Center

    Long, Melvin J.

    The teaching guide and course outline for a 12-week course in soils and foundations is designed to help student technicians in a two-year associate degree civil engineering technology program to obtain entry level employment as highway engineering aides, soil testing technicians, soil mappers, or construction inspectors. The seven teaching units…

  12. Foundations of Distinctive Feature Theory.

    ERIC Educational Resources Information Center

    Baltaxe, Christiane A. M.

    This treatise on the theoretical and historical foundations of distinctive feature theory traces the evolution of the distinctive features concept in the context of related notions current in linguistic theory, discusses the evolution of individual distinctive features, and criticizes certain acoustic and perceptual correlates attributed to these…

  13. Epistemological Foundations of School Science.

    ERIC Educational Resources Information Center

    Izquierdo-Aymerich, Merce; Aduriz-Bravo, Agustin

    2003-01-01

    Presents a theoretical framework that provides foundations for school science and defines some research problems. Begins with what is already known about students' models and cognition in order to construct proposals of didactical intervention. Proposes an analogous model for school science in which experimentation and language play the key roles.…

  14. Cognitive Foundations for Visual Analytics

    SciTech Connect

    Greitzer, Frank L.; Noonan, Christine F.; Franklin, Lyndsey

    2011-02-25

    In this report, we provide an overview of scientific/technical literature on information visualization and VA. Topics discussed include an update and overview of the extensive literature search conducted for this study, the nature and purpose of the field, major research thrusts, and scientific foundations. We review methodologies for evaluating and measuring the impact of VA technologies as well as taxonomies that have been proposed for various purposes to support the VA community. A cognitive science perspective underlies each of these discussions.

  15. Auditory midbrain implant: research and development towards a second clinical trial.

    PubMed

    Lim, Hubert H; Lenarz, Thomas

    2015-04-01

    The cochlear implant is considered one of the most successful neural prostheses to date, which was made possible by visionaries who continued to develop the cochlear implant through multiple technological and clinical challenges. However, patients without a functional auditory nerve or implantable cochlea cannot benefit from a cochlear implant. The focus of the paper is to review the development and translation of a new type of central auditory prosthesis for this group of patients that is known as the auditory midbrain implant (AMI) and is designed for electrical stimulation within the inferior colliculus. The rationale and results for the first AMI clinical study using a multi-site single-shank array will be presented initially. Although the AMI has achieved encouraging results in terms of safety and improvements in lip-reading capabilities and environmental awareness, it has not yet provided sufficient speech perception. Animal and human data will then be presented to show that a two-shank AMI array can potentially improve hearing performance by targeting specific neurons of the inferior colliculus. A new two-shank array, stimulation strategy, and surgical approach are planned for the AMI that are expected to improve hearing performance in the patients who will be implanted in an upcoming clinical trial funded by the National Institutes of Health. Positive outcomes from this clinical trial will motivate new efforts and developments toward improving central auditory prostheses for those who cannot sufficiently benefit from cochlear implants. This article is part of a Special Issue entitled <Lasker Award>.

  16. Vertical Axis Wind Turbine Foundation parameter study

    SciTech Connect

    Lodde, P.F.

    1980-07-01

    The dynamic failure criterion governing the dimensions of prototype Vertical Axis Wind Turbine Foundations is treated as a variable parameter. The resulting change in foundation dimensions and costs is examined.

  17. Founding a Foundation: A Mini Case Study.

    ERIC Educational Resources Information Center

    Lake, Dale B.

    1981-01-01

    Lists factors contributing to the need for increased fund raising in community colleges. Discusses advantages of a foundation as a means of obtaining private funds. Delineates specifics of establishing, organizing, and implementing the Kalamazoo Valley Community College Foundation. (DMM)

  18. Grantmaking to School Districts: Lessons for Foundations

    ERIC Educational Resources Information Center

    Coffman, Julia; Weiss, Heather; Harris, Erin; Little, Priscilla M. D.

    2010-01-01

    This brief offers lessons and best practices from foundations across the country on grantmaking to school districts. It offers advice to foundations that are considering school district investments for the first time. It also offers a useful "check" to more experienced foundations that want to examine their thinking and approaches against the…

  19. A Foundation Manual for California Community Colleges.

    ERIC Educational Resources Information Center

    Anderson, James M., Ed.; And Others

    Designed to aid the development and organization of effective college foundations in California, this reference guide reviews the purposes of foundations and the steps in their organization, providing sample documents from existing foundations. The manual is divided into 11 sections, the first of which discusses reasons for establishing…

  20. The Community College Foundation Manual & Guide.

    ERIC Educational Resources Information Center

    Anderson, James M., Comp.; Snyder, Tom, Comp.

    This collection of resources and information about community college foundations includes brief articles, selected data, materials from foundations, sample mission statements and articles of incorporation, sample forms and correspondence, relevant educational legislation, and other related materials from specific active foundations at two-year…

  1. Report on Illinois Public Community College Foundations.

    ERIC Educational Resources Information Center

    Illinois Community Coll. Board, Springfield.

    At the request of the Illinois Community College Board's (ICCB's) Committee on Foundations, the ICCB surveyed the state's public community college district to determine the purposes, resources, and activities of the colleges' foundations. The study found that all of the community college districts, except one, have foundations to assist them in…

  2. Bernard van Leer Foundation Annual Report 1996.

    ERIC Educational Resources Information Center

    Bernard Van Leer Foundation, The Hague (Netherlands).

    This document provides an annual report and financial review for 1996 of the Bernard van Leer Foundation, a private institution created in 1949 for broad humanitarian purposes. Following a summary by the executive director of the Foundation, the report includes a description of the foundation and its grants. It then lists, by country, the major…

  3. Bernard van Leer Foundation Annual Report, 1999.

    ERIC Educational Resources Information Center

    Bernard Van Leer Foundation, The Hague (Netherlands).

    This annual report details the activities and financial status for 1999 of the Bernard van Leer Foundation, a private institution created in 1949 for broad humanitarian purposes. Following the introduction by the chairman of the Foundation's board of trustees, the report of the executive director details activities during the Foundation's fiftieth…

  4. Bernard van Leer Foundation. Annual Report 1997.

    ERIC Educational Resources Information Center

    Bernard Van Leer Foundation, The Hague (Netherlands).

    This document provides an annual report and financial review of the Bernard van Leer Foundation, a private institution created in 1949 for broad humanitarian purposes. Following an introduction by the chairman of the Foundation's board of trustees, a report of the executive director details the first full-year of implementation of the Foundation's…

  5. Beyond Dependency: Strategies for Saving Foundations

    ERIC Educational Resources Information Center

    Schutz, Aaron; Butin, Dan

    2013-01-01

    The foundations field cannot sustain itself in its present condition. A range of complex forces have combined to marginalize foundations over the past few decades. The decline of this field as a separate discipline in schools of education has been abetted by the fact that foundations is generally a "service provider" to other programs.…

  6. Philanthropy and Private Foundations: Expanding Revenue Sources

    ERIC Educational Resources Information Center

    Drummer, Carlee; Marshburn, Roxann

    2014-01-01

    As community colleges seek new revenue streams, philanthropic organizations, including college foundations and private funders, have already begun to influence both revenues and college programming. This chapter discusses the current role of philanthropy, especially private foundations such as the Lumina Foundation for Education and the Bill and…

  7. Deontological foundations for medical ethics?

    PubMed

    Gillon, R

    1985-05-01

    Gillon outlines the principles of the deontological, or duty-based, group of moral theories in one of a series of British Medical Journal articles on the philosophical foundations of medical ethics. He differentiates between monistic theories, such as Immanuel Kant's, which rely on a single moral principle, and pluralistic theories, such as that of W.D. Ross, which rely on several principles that potentially could conflict. He summarizes the contributions of Kant and Ross to the development of deontological thought, then concludes his essay with brief paragraphs on other deontological approaches to the resolution of conflicting moral principles.

  8. EVOLUTIONARY FOUNDATIONS FOR MOLECULAR MEDICINE

    PubMed Central

    Nesse, Randolph M.; Ganten, Detlev; Gregory, T. Ryan; Omenn, Gilbert S.

    2015-01-01

    Evolution has long provided a foundation for population genetics, but many major advances in evolutionary biology from the 20th century are only now being applied in molecular medicine. They include the distinction between proximate and evolutionary explanations, kin selection, evolutionary models for cooperation, and new strategies for tracing phylogenies and identifying signals of selection. Recent advances in genomics are further transforming evolutionary biology and creating yet more opportunities for progress at the interface of evolution with genetics, medicine, and public health. This article reviews 15 evolutionary principles and their applications in molecular medicine in hopes that readers will use them and others to speed the development of evolutionary molecular medicine. PMID:22544168

  9. The shifting foundations of nursing.

    PubMed

    Law, Kate; Aranda, Kay

    2010-08-01

    In this paper we argue that the concerns generated by the development of Foundation Degrees and the Assistant and Associate Practitioner roles have rekindled some of the unresolved debates regarding the status and identity of nursing and nurses. Through the application of the sociological theories of professionalisation and nostalgia we have identified the shifting and unresolved nature of nursing. We argue that these theories continue to have resonance in the current climate of change and 'upskilling' of the health care workforce and argue, that the shifts illuminated are perhaps so significant as to demonstrate that we have entered a post-nursing era.

  10. Foundations for offshore wind turbines.

    PubMed

    Byrne, B W; Houlsby, G T

    2003-12-15

    An important engineering challenge of today, and a vital one for the future, is to develop and harvest alternative sources of energy. This is a firm priority in the UK, with the government setting a target of 10% of electricity from renewable sources by 2010. A component central to this commitment will be to harvest electrical power from the vast energy reserves offshore, through wind turbines or current or wave power generators. The most mature of these technologies is that of wind, as much technology transfer can be gained from onshore experience. Onshore wind farms, although supplying 'green energy', tend to provoke some objections on aesthetic grounds. These objections can be countered by locating the turbines offshore, where it will also be possible to install larger capacity turbines, thus maximizing the potential of each wind farm location. This paper explores some civil-engineering problems encountered for offshore wind turbines. A critical component is the connection of the structure to the ground, and in particular how the load applied to the structure is transferred safely to the surrounding soil. We review previous work on the design of offshore foundations, and then present some simple design calculations for sizing foundations and structures appropriate to the wind-turbine problem. We examine the deficiencies in the current design approaches, and the research currently under way to overcome these deficiencies. Designs must be improved so that these alternative energy sources can compete economically with traditional energy suppliers. PMID:14667305

  11. Foundations for offshore wind turbines.

    PubMed

    Byrne, B W; Houlsby, G T

    2003-12-15

    An important engineering challenge of today, and a vital one for the future, is to develop and harvest alternative sources of energy. This is a firm priority in the UK, with the government setting a target of 10% of electricity from renewable sources by 2010. A component central to this commitment will be to harvest electrical power from the vast energy reserves offshore, through wind turbines or current or wave power generators. The most mature of these technologies is that of wind, as much technology transfer can be gained from onshore experience. Onshore wind farms, although supplying 'green energy', tend to provoke some objections on aesthetic grounds. These objections can be countered by locating the turbines offshore, where it will also be possible to install larger capacity turbines, thus maximizing the potential of each wind farm location. This paper explores some civil-engineering problems encountered for offshore wind turbines. A critical component is the connection of the structure to the ground, and in particular how the load applied to the structure is transferred safely to the surrounding soil. We review previous work on the design of offshore foundations, and then present some simple design calculations for sizing foundations and structures appropriate to the wind-turbine problem. We examine the deficiencies in the current design approaches, and the research currently under way to overcome these deficiencies. Designs must be improved so that these alternative energy sources can compete economically with traditional energy suppliers.

  12. Partnering: The foundation for performance

    SciTech Connect

    Edelman, L.

    1994-12-31

    Over the past several decades, the US has experienced an unprecedented increase in the number of disputes in litigation. The environmental area, particularly contracts involving remediation projects, have not been immune from this situation. The adverse impact of this litigation mindset on the financial and personnel resources of the contracting parties has escalated and the detrimental effect on contractual relationships has become more apparent. Both owners and contractors are confronted with unrealized contract expectations, hostility on the jobsite and disappointment in the traditional dispute resolution processes. Relying exclusively on litigation when negotiations fail to settle contract disputes is time consuming, costly and frustrating. Now in the 1990s, the Corps along with the construction industry are moving to establish a new relationship beneficial to all contracting parties that focus on disputes avoidance. This new relationship is fostered by a process called Partnering. In undertaking environmental remediation work, Partnering can lay the foundation for a successful relationship among all involved parties.

  13. The foundation of kinship: Households

    PubMed Central

    Leonetti, Donna L.; Chabot-Hanowell, Benjamin

    2011-01-01

    Men’s hunting has dominated the discourse on energy capture and flow in the past decade or so. We turn to women’s roles as critical to household formation, pair bonding and intergenerational bonds. Their pivotal contributions in food processing and distribution likely promoted kinship, both genetic and affinal, and appear to be the foundation from which households evolved. With conscious recognition of household social units, variable cultural constructions of human kinship systems could emerge that were sensitive to environmental and technological conditions. Kinship dramatically altered the organization of resource access for our species creating what we term “kinship ecologies.” We present simple mathematical models to show how hunting leads to dependence on women’s contributions, bonds men to women and generations together. Kinship, as it organized transfers of food and labor energy centered on women, also became integrated with the biological evolution of human reproduction and life history. PMID:21799658

  14. Foundation Depth for Bridge Piers

    NASA Astrophysics Data System (ADS)

    Veerappadevaru, G.; Gangadharaiah, T.; Jagadeesh, T. R.

    2013-09-01

    The safety of bridge piers built in rivers having the bed is one of the prime aspects in the study of scouring process around bridge piers. The stability of bridge piers depends on the depth of foundation provided below maximum scour level. The stability analysis of bridge piers is carried based on moment of forces acting on the caisson pier when the pier slides and tilts slightly in downstream from its position. The experiments are conducted for three pier shapes on two sediment beds and for different flow conditions. The curves indicating the stability limits are compared with Lacey's recommendations which are used in present day practice in India. The analysis presented here indicates that the Lacey's recommendation for railway bridges is safe and for some cases of the road bridges depends on grip length, angle of tilt and weight of caisson.

  15. Emotional foundations of cognitive control.

    PubMed

    Inzlicht, Michael; Bartholow, Bruce D; Hirsh, Jacob B

    2015-03-01

    Often seen as the paragon of higher cognition, here we suggest that cognitive control is dependent on emotion. Rather than asking whether control is influenced by emotion, we ask whether control itself can be understood as an emotional process. Reviewing converging evidence from cybernetics, animal research, cognitive neuroscience, and social and personality psychology, we suggest that cognitive control is initiated when goal conflicts evoke phasic changes to emotional primitives that both focus attention on the presence of goal conflicts and energize conflict resolution to support goal-directed behavior. Critically, we propose that emotion is not an inert byproduct of conflict but is instrumental in recruiting control. Appreciating the emotional foundations of control leads to testable predictions that can spur future research.

  16. Emotional foundations of cognitive control

    PubMed Central

    Inzlicht, Michael; Bartholow, Bruce D.; Hirsh, Jacob B.

    2015-01-01

    Often seen as the paragon of higher cognition, here we suggest that cognitive control is dependent on emotion. Rather than asking whether control is influenced by emotion, we ask whether control itself can be understood as an emotional process. Reviewing converging evidence from cybernetics, animal research, cognitive neuroscience, and social and personality psychology, we suggest that cognitive control is initiated when goal conflicts evoke phasic changes to emotional primitives that both focus attention on the presence of goal conflicts and energize conflict resolution to support goal-directed behavior. Critically, we propose that emotion is not an inert byproduct of conflict but is instrumental in recruiting control. Appreciating the emotional foundations of control leads to testable predictions that can spur future research. PMID:25659515

  17. Phase II randomized clinical trial evaluating neoadjuvant chemotherapy regimens with weekly paclitaxel or eribulin followed by doxorubicin and cyclophosphamide in women with locally advanced HER2-negative breast cancer: NSABP Foundation Study FB-9.

    PubMed

    Abraham, Jame; Robidoux, André; Tan, Antoinette R; Limentani, Steven; Sturtz, Keren; Shalaby, Ibrahim; Alcorn, Hope; Buyse, Marc E; Wolmark, Norman; Jacobs, Samuel A

    2015-07-01

    Locally advanced breast cancer (LABC) is a good setting in which to monitor response to neoadjuvant chemotherapy, to downsize the tumor (which facilitates breast-conserving surgery), and to test newer agents in untreated patients. Eribulin (E) has shown activity in patients who have undergone previous taxane, anthracycline, and capecitabine treatment. We aimed to evaluate the neoadjuvant use of E followed by doxorubicin and cyclophosphamide (AC) in patients with HER2-negative LABC, using as a control a randomized group of women who received weekly paclitaxel (WP). Fifty women with LABC were accrued January-August 2013. Patients were randomized (1:2) to receive either WP (N = 19) for 12 treatments or E (N = 31) every 3 weeks for 4 cycles followed by AC every 3 weeks for 4 cycles before surgery. 17/19 patients who took WP and 25/30 who took E completed all cycles. Patients were evaluated by clinical examination and breast MRI at baseline and after completion of E or WP. Surgical pCR in breast and lymph nodes was determined by a local pathologist following chemotherapy. Forty-nine patients received ≥1 dose of neoadjuvant chemotherapy and are included in this analysis. Forty-eight underwent surgery; one had disease that was inoperable (on E) and is included as no-pCR patient. 17/19 of these patients who took WP completed 12 doses; 28/30 on E completed 4 cycles. Six discontinued treatment on WP, E, or AC. Both treatments were well tolerated. pCR on WP = 5/19(26 %) and on E = 5/30(17 %). Both regimens were equally well tolerated with no unexpected toxicities. pCR did not suggest higher activity with E than with other standard regimens in these LABC patients.

  18. National Urea Cycle Disorders Foundation

    MedlinePlus

    ... questions, NUCDF has collaborated with clinical investigators to design a patient-centered research study to gather evidence-based information to help inform families and healthcare providers about ...

  19. The Community College Foundation Today: A. History, Characteristics, and Assets.

    ERIC Educational Resources Information Center

    Angel, Dan; Gares, Dale

    1989-01-01

    Offers a historical perspective on the community college foundation, reviews 1987 research findings concerning foundation assets, lists 10 steps to establishing a foundation, and identifies key factors in organizational success. Describes the revitalization of the Citrus College Foundation. (DMM)

  20. Textural break foundation wall construction modules

    DOEpatents

    Phillips, Steven J.

    1990-01-01

    Below-grade, textural-break foundation wall structures are provided for inhibiting diffusion and advection of liquids and gases into and out from a surrounding hydrogeologic environment. The foundation wall structure includes a foundation wall having an interior and exterior surface and a porous medium disposed around a portion of the exterior surface. The structure further includes a modular barrier disposed around a portion of the porous medium. The modular barrier is substantially removable from the hydrogeologic environment.

  1. Mathematical foundation of quantum annealing

    SciTech Connect

    Morita, Satoshi; Nishimori, Hidetoshi

    2008-12-15

    Quantum annealing is a generic name of quantum algorithms that use quantum-mechanical fluctuations to search for the solution of an optimization problem. It shares the basic idea with quantum adiabatic evolution studied actively in quantum computation. The present paper reviews the mathematical and theoretical foundations of quantum annealing. In particular, theorems are presented for convergence conditions of quantum annealing to the target optimal state after an infinite-time evolution following the Schroedinger or stochastic (Monte Carlo) dynamics. It is proved that the same asymptotic behavior of the control parameter guarantees convergence for both the Schroedinger dynamics and the stochastic dynamics in spite of the essential difference of these two types of dynamics. Also described are the prescriptions to reduce errors in the final approximate solution obtained after a long but finite dynamical evolution of quantum annealing. It is shown there that we can reduce errors significantly by an ingenious choice of annealing schedule (time dependence of the control parameter) without compromising computational complexity qualitatively. A review is given on the derivation of the convergence condition for classical simulated annealing from the view point of quantum adiabaticity using a classical-quantum mapping.

  2. Evolutionary foundations for cancer biology

    PubMed Central

    Aktipis, C Athena; Nesse, Randolph M

    2013-01-01

    New applications of evolutionary biology are transforming our understanding of cancer. The articles in this special issue provide many specific examples, such as microorganisms inducing cancers, the significance of within-tumor heterogeneity, and the possibility that lower dose chemotherapy may sometimes promote longer survival. Underlying these specific advances is a large-scale transformation, as cancer research incorporates evolutionary methods into its toolkit, and asks new evolutionary questions about why we are vulnerable to cancer. Evolution explains why cancer exists at all, how neoplasms grow, why cancer is remarkably rare, and why it occurs despite powerful cancer suppression mechanisms. Cancer exists because of somatic selection; mutations in somatic cells result in some dividing faster than others, in some cases generating neoplasms. Neoplasms grow, or do not, in complex cellular ecosystems. Cancer is relatively rare because of natural selection; our genomes were derived disproportionally from individuals with effective mechanisms for suppressing cancer. Cancer occurs nonetheless for the same six evolutionary reasons that explain why we remain vulnerable to other diseases. These four principles—cancers evolve by somatic selection, neoplasms grow in complex ecosystems, natural selection has shaped powerful cancer defenses, and the limitations of those defenses have evolutionary explanations—provide a foundation for understanding, preventing, and treating cancer. PMID:23396885

  3. Pharmacological foundations of cardio-oncology.

    PubMed

    Minotti, Giorgio; Salvatorelli, Emanuela; Menna, Pierantonio

    2010-07-01

    Anthracyclines and many other antitumor drugs induce cardiotoxicity that occurs "on treatment" or long after completing chemotherapy. Dose reductions limit the incidence of early cardiac events but not that of delayed sequelae, possibly indicating that any dose level of antitumor drugs would prime the heart to damage from sequential stressors. Drugs targeted at tumor-specific moieties raised hope for improving the cardiovascular safety of antitumor therapies; unfortunately, however, many such drugs proved unable to spare the heart, aggravated cardiotoxicity induced by anthracyclines, or were safe in selected patients of clinical trials but not in the general population. Cardio-oncology is the discipline aimed at monitoring the cardiovascular safety of antitumor therapies. Although popularly perceived as a clinical discipline that brings oncologists and cardiologists working together, cardio-oncology is in fact a pharmacology-oriented translational discipline. The cardiovascular performance of survivors of cancer will only improve if clinicians joined pharmacologists in the search for new predictive models of cardiotoxicity or mechanistic approaches to explain how a given drug might switch from causing systolic failure to inducing ischemia. The lifetime risk of cardiotoxicity from antitumor drugs needs to be reconciled with the identification of long-lasting pharmacological signatures that overlap with comorbidities. Research on targeted drugs should be reshaped to appreciate that the terminal ballistics of new "magic bullets" might involve cardiomyocytes as innocent bystanders. Finally, the concepts of prevention and treatment need to be tailored to the notion that late-onset cardiotoxicity builds on early asymptomatic cardiotoxicity. The heart of cardio-oncology rests with such pharmacological foundations.

  4. Foundations and Higher Education: Whose Agenda?

    ERIC Educational Resources Information Center

    Schneider, John C.

    2007-01-01

    Grant programs that had been relatively open-ended were now tightly drawn, grounded in the foundations' own carefully articulated take on issues and receptive only to proposals that responded appropriately. Initiative and creativity had shifted heavily from prospective grantee to grantor. As foundations embraced this funding-by-agenda, it burdened…

  5. Liberating Foundations of Art and Design

    ERIC Educational Resources Information Center

    Lerner, Fern

    2012-01-01

    Research concerning the basic course known as Foundations of Art and Design strengthens the pedagogical approach for K-16 art and design education. The version of Foundations introduced to America by Josef Albers, although hardly changed, is shown to have continued, timeless relevance. Next, a sequential, implicit logic is revealed in linking the…

  6. Bernard van Leer Foundation Annual Report, 2001.

    ERIC Educational Resources Information Center

    Bernard Van Leer Foundation, The Hague (Netherlands).

    This annual report for 2001 describes the year's activities, achievements, and financial status of the Bernard van Leer Foundation, a private foundation based in The Netherlands operating internationally to improve opportunities for young children from birth to age 7 living in circumstances of social and economic disadvantage. Following the…

  7. Bernard van Leer Foundation Annual Report 1998.

    ERIC Educational Resources Information Center

    Bernard Van Leer Foundation, The Hague (Netherlands).

    This document provides an annual report and financial review for 1998 of the Bernard van Leer Foundation, a private institution created in 1949 for broad humanitarian purposes. Following an introduction by chairman of the Foundation's board of trustees, a report of the executive director details the second year of implementation of the…

  8. Bernard van Leer Foundation Annual Report, 2000.

    ERIC Educational Resources Information Center

    Bernard Van Leer Foundation, The Hague (Netherlands).

    This annual report for 2000 describes the year's activities, achievements, and financial status of the Bernard van Leer Foundation, a private foundation based in The Netherlands that operates internationally to improve opportunities for young children from birth to age 7 living in circumstances of social and economic disadvantage. Following an…

  9. Bernard van Leer Foundation Annual Report, 2002.

    ERIC Educational Resources Information Center

    Bernard Van Leer Foundation, The Hague (Netherlands).

    This annual report for 2002 describes the year's activities, achievements, and financial status of the Bernard van Leer Foundation, a private foundation based in The Netherlands operating internationally to improve opportunities for young children from birth to age 7 living in circumstances of social and economic disadvantage. Following the…

  10. Inter-American Foundation Annual Report 1987.

    ERIC Educational Resources Information Center

    Inter-American Foundation, Rosslyn, VA.

    This annual report from the Inter-American Foundation (IAF), a federal development agency, includes letters from foundation officials describing the IAF-funded work in poverty areas of Latin America and the Caribbean. The report describes IAF's In-Country Support System (ICS), staffed by local professionals who assist grantees and report their…

  11. Peace Education: Exploring Some Philosophical Foundations

    ERIC Educational Resources Information Center

    Page, James S.

    2004-01-01

    Peace education has been recognized as an important aspect of social education for the past three decades. The critical literature as well as official documents, however, have given little attention to its philosophical foundations. This essay explores these foundations in the ethics of (1) virtue, (2) consequentialism, (3) aesthetics, (4)…

  12. Support for Science from a Foundation Perspective.

    ERIC Educational Resources Information Center

    Finberg, Barbara D.

    1990-01-01

    Presents examples of unique contributions of individuals at private foundations to the emergence and growth of scientific research on child and adolescent development. Discusses specific leaders of the Carnegie Foundation and the Laura Spelman Rockefeller Memorial Fund to demonstrate how influential individuals can be in determining major…

  13. Foundations of Education: Texts and the Canon.

    ERIC Educational Resources Information Center

    Gottlieb, Esther E.

    This paper attempts to outline the textual canon of the foundations of education in U.S. teacher education programs. Background research for the project included a review of selected texts and samples of course syllabi. Analysis of the contents and prefaces of the two volumes of "Reading in the Foundations of Education" (published in 1941 by…

  14. Kellogg Foundation Still Investing in People

    ERIC Educational Resources Information Center

    Abdul-Alim, Jamaal

    2011-01-01

    When the W.K. Kellogg Foundation first approached a group of tribal college presidents in 1994 with a $23 million grant for a handful of their institutions, the tribal college leaders did not exactly trip over themselves to get the money. They wanted it to be split among all of them, and the foundation honored the tribal college leaders' wish.…

  15. On the Need to Live Educational Foundations

    ERIC Educational Resources Information Center

    Schubert, William H.

    2013-01-01

    William H. Schubert, retired faculty member at the University of Illinois, Chicago, reflects on his teaching career and the loss of "educational foundations." Schubert states that "Foundations of Education" are being pushed toward the precipice of extinction. He describes a loss of "back-to-basics" education with a…

  16. Energy foundations for sustainable development

    SciTech Connect

    Sather, N.F.

    1992-01-01

    Worldwide, more than three-quarters of our energy needs are obtained from nonrenewable reserves of coal, oil, gas, and uranium. The unavoidable outcome of our present path is the depletion of all non-renewable energy resources. Further exacerbating the energy picture is the mounting cost of mitigating the adverse environmental and health impacts of energy use. Problems ranging from acid rain and radioactive waste storage to the potential for widespread environmental disaster that could result from the buildup of greenhouse gases in the atmosphere have made it that the earth's capacity to absorb the waste products of energy use without serious consequences is being severely strained. Potential supply shortages and mounting costs for the energy component of our industrial enterprise will increasingly undermine our ability to sustain global economic development. Strong positive actions that shore up the energy foundations of our economy arc called for. The purpose of this presentation is to focus attention on two such proactive steps which, though insufficient to the task by themselves, are nevertheless crucial to any effective plan for heading off the recessionary tendencies of our growing energy supply and cost dilemma. The first of these essential steps is to develop a much better arrangement than we currently have for including all costs for the adverse health and environmental impacts of industrial production in the price paid by consumers for fuels, electricity, and manufactured goods. The second essential action is to expand our R D effort to develop new manufacturing processes and new materials and products that meet our needs for power, fuels and consumer goods at lower cost, greater efficiency, and with reduced environmental cost.

  17. Energy foundations for sustainable development

    SciTech Connect

    Sather, N.F.

    1992-09-01

    Worldwide, more than three-quarters of our energy needs are obtained from nonrenewable reserves of coal, oil, gas, and uranium. The unavoidable outcome of our present path is the depletion of all non-renewable energy resources. Further exacerbating the energy picture is the mounting cost of mitigating the adverse environmental and health impacts of energy use. Problems ranging from acid rain and radioactive waste storage to the potential for widespread environmental disaster that could result from the buildup of greenhouse gases in the atmosphere have made it that the earth`s capacity to absorb the waste products of energy use without serious consequences is being severely strained. Potential supply shortages and mounting costs for the energy component of our industrial enterprise will increasingly undermine our ability to sustain global economic development. Strong positive actions that shore up the energy foundations of our economy arc called for. The purpose of this presentation is to focus attention on two such proactive steps which, though insufficient to the task by themselves, are nevertheless crucial to any effective plan for heading off the recessionary tendencies of our growing energy supply and cost dilemma. The first of these essential steps is to develop a much better arrangement than we currently have for including all costs for the adverse health and environmental impacts of industrial production in the price paid by consumers for fuels, electricity, and manufactured goods. The second essential action is to expand our R&D effort to develop new manufacturing processes and new materials and products that meet our needs for power, fuels and consumer goods at lower cost, greater efficiency, and with reduced environmental cost.

  18. Density functional theory: Foundations reviewed

    NASA Astrophysics Data System (ADS)

    Kryachko, Eugene S.; Ludeña, Eduardo V.

    2014-11-01

    Guided by the above motto (quotation), we review a broad range of issues lying at the foundations of Density Functional Theory, DFT, a theory which is currently omnipresent in our everyday computational study of atoms and molecules, solids and nano-materials, and which lies at the heart of modern many-body computational technologies. The key goal is to demonstrate that there are definitely the ways to improve DFT. We start by considering DFT in the larger context provided by reduced density matrix theory (RDMT) and natural orbital functional theory (NOFT), and examine the implications that N-representability conditions on the second-order reduced density matrix (2-RDM) have not only on RDMT and NOFT but, also, by extension, on the functionals of DFT. This examination is timely in view of the fact that necessary and sufficient N-representability conditions on the 2-RDM have recently been attained. In the second place, we review some problems appearing in the original formulation of the first Hohenberg-Kohn theorem which is still a subject of some controversy. In this vein we recall Lieb's comment on this proof and the extension to this proof given by Pino et al. (2009), and in this context examine the conditions that must be met in order that the one-to-one correspondence between ground-state densities and external potentials remains valid for finite subspaces (namely, the subspaces where all Kohn-Sham solutions are obtained in practical applications). We also consider the issue of whether the Kohn-Sham equations can be derived from basic principles or whether they are postulated. We examine this problem in relation to ab initio DFT. The possibility of postulating arbitrary Kohn-Sham-type equations, where the effective potential is by definition some arbitrary mixture of local and non-local terms, is discussed. We also deal with the issue of whether there exists a universal functional, or whether one should advocate instead the construction of problem

  19. The Foundation-Institution Partnership: The Role of Institutionally Related Foundations in Public Higher Education

    ERIC Educational Resources Information Center

    Bass, David

    2010-01-01

    Institutionally related foundations have played a vital role in raising and managing private resources in support of public institutions of higher education. Unlike private grant-making foundations, college and university foundations are typically incorporated as public charities under section 501(c)(3) of the Internal Revenue Code. Although they…

  20. Nonprofit foundations spur translational research.

    PubMed

    Zaratin, Paola; Battaglia, Mario Alberto; Abbracchio, Maria P

    2014-11-01

    Every year, hundreds of promising basic discoveries in the pharmacological field are lost and will never have a chance to be exploited for patients due to difficulties in clinical translation. This is especially true for most neurodegenerative disorders lacking disease-modifying therapies. Here we present the current scenario and our vision of a 'collective-impact' multistakeholder approach to expedite the development of new drugs.

  1. Density functional theory: Foundations reviewed

    NASA Astrophysics Data System (ADS)

    Kryachko, Eugene S.; Ludeña, Eduardo V.

    2014-11-01

    Guided by the above motto (quotation), we review a broad range of issues lying at the foundations of Density Functional Theory, DFT, a theory which is currently omnipresent in our everyday computational study of atoms and molecules, solids and nano-materials, and which lies at the heart of modern many-body computational technologies. The key goal is to demonstrate that there are definitely the ways to improve DFT. We start by considering DFT in the larger context provided by reduced density matrix theory (RDMT) and natural orbital functional theory (NOFT), and examine the implications that N-representability conditions on the second-order reduced density matrix (2-RDM) have not only on RDMT and NOFT but, also, by extension, on the functionals of DFT. This examination is timely in view of the fact that necessary and sufficient N-representability conditions on the 2-RDM have recently been attained. In the second place, we review some problems appearing in the original formulation of the first Hohenberg-Kohn theorem which is still a subject of some controversy. In this vein we recall Lieb's comment on this proof and the extension to this proof given by Pino et al. (2009), and in this context examine the conditions that must be met in order that the one-to-one correspondence between ground-state densities and external potentials remains valid for finite subspaces (namely, the subspaces where all Kohn-Sham solutions are obtained in practical applications). We also consider the issue of whether the Kohn-Sham equations can be derived from basic principles or whether they are postulated. We examine this problem in relation to ab initio DFT. The possibility of postulating arbitrary Kohn-Sham-type equations, where the effective potential is by definition some arbitrary mixture of local and non-local terms, is discussed. We also deal with the issue of whether there exists a universal functional, or whether one should advocate instead the construction of problem

  2. Seismic isolation of two dimensional periodic foundations

    SciTech Connect

    Yan, Y.; Mo, Y. L.; Laskar, A.; Cheng, Z.; Shi, Z.; Menq, F.; Tang, Y.

    2014-07-28

    Phononic crystal is now used to control acoustic waves. When the crystal goes to a larger scale, it is called periodic structure. The band gaps of the periodic structure can be reduced to range from 0.5 Hz to 50 Hz. Therefore, the periodic structure has potential applications in seismic wave reflection. In civil engineering, the periodic structure can be served as the foundation of upper structure. This type of foundation consisting of periodic structure is called periodic foundation. When the frequency of seismic waves falls into the band gaps of the periodic foundation, the seismic wave can be blocked. Field experiments of a scaled two dimensional (2D) periodic foundation with an upper structure were conducted to verify the band gap effects. Test results showed the 2D periodic foundation can effectively reduce the response of the upper structure for excitations with frequencies within the frequency band gaps. When the experimental and the finite element analysis results are compared, they agree well with each other, indicating that 2D periodic foundation is a feasible way of reducing seismic vibrations.

  3. Foundations for a theory of gravitation theories

    NASA Technical Reports Server (NTRS)

    Thorne, K. S.; Lee, D. L.; Lightman, A. P.

    1972-01-01

    A foundation is laid for future analyses of gravitation theories. This foundation is applicable to any theory formulated in terms of geometric objects defined on a 4-dimensional spacetime manifold. The foundation consists of (1) a glossary of fundamental concepts; (2) a theorem that delineates the overlap between Lagrangian-based theories and metric theories; (3) a conjecture (due to Schiff) that the Weak Equivalence Principle implies the Einstein Equivalence Principle; and (4) a plausibility argument supporting this conjecture for the special case of relativistic, Lagrangian-based theories.

  4. Relativistic Navigation: A Theoretical Foundation

    NASA Technical Reports Server (NTRS)

    Turyshev, Slava G.

    1996-01-01

    We present a theoretical foundation for relativistic astronomical measurements in curved space-time. In particular, we discuss a new iterative approach for describing the dynamics of an isolated astronomical N-body system in metric theories of gravity. To do this, we generalize the Fock-Chandrasekhar method of the weak-field and slow-motion approximation (WFSMA) and develop a theory of relativistic reference frames (RF's) for a gravitationally bounded many-extended-body problem. In any proper RF constructed in the immediate vicinity of an arbitrary body, the N-body solutions of the gravitational field equations are formally presented as a sum of the Riemann-flat inertial space-time, the gravitational field generated by the body itself, the unperturbed solutions for each body in the system transformed to the coordinates of this proper RF, and the gravitational interaction term. We develop the basic concept of a general WFSMA theory of the celestial RF's applicable to a wide class of metric theories of gravity and an arbitrary model of matter distribution. We apply the proposed method to general relativity. Celestial bodies are described using a perfect fluid model; as such, they possess any number of internal mass and current multipole moments that explicitly characterize their internal structures. The obtained relativistic corrections to the geodetic equations of motion arise because of a coupling of the bodies' multiple moments to the surrounding gravitational field. The resulting relativistic transformations between the different RF's extend the Poincare group to the motion of deformable self-gravitating bodies. Within the present accuracy of astronomical measurements we discuss the properties of the Fermi-normal-like proper RF that is defined in the immediate vicinity of the extended compact bodies. We further generalize the proposed approximation method and include two Eddington parameters (gamma, Beta). This generalized approach was used to derive the

  5. Sudden Arrhythmia Death Syndromes (SADS) Foundation

    MedlinePlus

    ... SADS Foundation and John Hopkins Hospital Division of Cardiology are hosting a family support and educational meeting ... Baltimore/DC area families with cardiac arrhythmias. Sports Cardiology & Sudden Cardiac Arrest in the Young Conference 01/ ...

  6. Sartre: A Possible Foundation for Educational Theory.

    ERIC Educational Resources Information Center

    Burstow, Bonnie

    1983-01-01

    The claim by Khemais Benhamida and others that Jean-Paul Sartre's philosophy is too hostile and restrictive to serve as the foundation of progressive educational theory is based on an incomplete understanding of the philosopher's work. (IS)

  7. Veatch's new foundation for medical ethics.

    PubMed

    Kultgen, J

    1985-11-01

    Robert M. Veatch proposes a "triple contract theory" as a new foundation for medical ethics. His criticisms of unilateral "physician ethics" are sound, but uncertainty as to whether he is proposing merely imaginary or real contracts vitiates his constructive arguments. If the former, he is recommending a minor heuristic device for thinking about ethics, not a foundation. If the latter, his proposal is utterly impractical and a medical covenant will have to be developed another way.

  8. Health legacy foundations: a new census.

    PubMed

    Niggel, Sabrina Jones; Brandon, William P

    2014-01-01

    Health care merger and acquisition activity has increased since enactment of the Affordable Care Act in 2010. Proceeds from transactions involving nonprofit hospitals, health systems, and health plans will endow philanthropic foundations, collectively known as health legacy foundations. Building on work by Grantmakers In Health, we undertook a systematic search for these foundations and generated a newly updated, comprehensive database. We found 306 organizations in forty-three states that have been endowed with proceeds from the sale, merger, lease, joint venture, or other restructuring of nonprofit health care assets. These health legacy foundations had $26.2 billion in assets in 2010. Concentrated in the southern United States, foundations originating from hospitals and specialty care facilities (86.6 percent) held mean assets of $64.7 million per funder and typically restricted grants to local communities. Foundations formed from health plans (13.4 percent) held higher mean assets ($222 million), usually served larger areas, and were more likely to engage in health care advocacy. Recent transactions involving smaller and stand-alone nonprofit hospitals will infuse many more communities with unprecedented charitable wealth.

  9. Health legacy foundations: a new census.

    PubMed

    Niggel, Sabrina Jones; Brandon, William P

    2014-01-01

    Health care merger and acquisition activity has increased since enactment of the Affordable Care Act in 2010. Proceeds from transactions involving nonprofit hospitals, health systems, and health plans will endow philanthropic foundations, collectively known as health legacy foundations. Building on work by Grantmakers In Health, we undertook a systematic search for these foundations and generated a newly updated, comprehensive database. We found 306 organizations in forty-three states that have been endowed with proceeds from the sale, merger, lease, joint venture, or other restructuring of nonprofit health care assets. These health legacy foundations had $26.2 billion in assets in 2010. Concentrated in the southern United States, foundations originating from hospitals and specialty care facilities (86.6 percent) held mean assets of $64.7 million per funder and typically restricted grants to local communities. Foundations formed from health plans (13.4 percent) held higher mean assets ($222 million), usually served larger areas, and were more likely to engage in health care advocacy. Recent transactions involving smaller and stand-alone nonprofit hospitals will infuse many more communities with unprecedented charitable wealth. PMID:24395949

  10. The foundation of self-esteem.

    PubMed

    Bailey, Joseph A

    2003-05-01

    Self-esteem is a simplistic term for varied and complex mental states pertaining to how one views oneself. It takes but little research in the voluminous literature to see the vagueness and inconsistencies in its various definitions. Even more problematic is the uncertainty concerning its foundational components. The importance of having a solid definition and specific ideas about the foundational components of self-esteem is that both pave the way to recognizing its causes; to predicting effects from those causes; and to organizing the trouble-shooting process for locating those philosophical flaws or psychological scars which lead to low self-esteem. The purpose of this paper is to offer a common ground for thinking about self-esteem at its most basic level. In order to distinguish the "basic level" from the rest of the components of self-esteem, let us liken it to a skyscraper building. Here, the focus is on the building's "underground foundation" and the base upon which that foundation rests. The base is a definition that allows for the assessment of the foundation. The underground foundation itself consists of the mental building blocks called self-meaning, self-identity, self-image, and self-concepts. To help illustrate their interactions, a few of the "masks" and "faces" of self-esteem will be mentioned. What is not being addressed is the "above ground structure"--those theories and manifestations dealt with by most mental health specialists.

  11. The foundation of self-esteem.

    PubMed Central

    Bailey, Joseph A.

    2003-01-01

    Self-esteem is a simplistic term for varied and complex mental states pertaining to how one views oneself. It takes but little research in the voluminous literature to see the vagueness and inconsistencies in its various definitions. Even more problematic is the uncertainty concerning its foundational components. The importance of having a solid definition and specific ideas about the foundational components of self-esteem is that both pave the way to recognizing its causes; to predicting effects from those causes; and to organizing the trouble-shooting process for locating those philosophical flaws or psychological scars which lead to low self-esteem. The purpose of this paper is to offer a common ground for thinking about self-esteem at its most basic level. In order to distinguish the "basic level" from the rest of the components of self-esteem, let us liken it to a skyscraper building. Here, the focus is on the building's "underground foundation" and the base upon which that foundation rests. The base is a definition that allows for the assessment of the foundation. The underground foundation itself consists of the mental building blocks called self-meaning, self-identity, self-image, and self-concepts. To help illustrate their interactions, a few of the "masks" and "faces" of self-esteem will be mentioned. What is not being addressed is the "above ground structure"--those theories and manifestations dealt with by most mental health specialists. PMID:12793795

  12. 75 FR 2844 - African Development Foundation, Board of Directors Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-19

    ...; ] AFRICAN DEVELOPMENT FOUNDATION African Development Foundation, Board of Directors Meeting Time: Tuesday, January 26, 2010, 8:30 a.m. to 1 p.m. Place: African Development Foundation, Conference Room, 1400...

  13. 75 FR 14418 - African Development Foundation, Board of Directors Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-25

    ...; ] AFRICAN DEVELOPMENT FOUNDATION African Development Foundation, Board of Directors Meeting Time: Tuesday, April 13, 2010, 9:30 a.m. to 1 p.m. Place: African Development Foundation, Conference Room, 1400...

  14. 75 FR 45600 - African Development Foundation, Board of Directors Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-03

    ...; ] AFRICAN DEVELOPMENT FOUNDATION African Development Foundation, Board of Directors Meeting Time: Tuesday, August 17, 2010, 8:30 a.m. to 1 p.m. Place: African Development Foundation, Conference Room, 1400...

  15. Cooperation: the foundation of improvement.

    PubMed

    Clemmer, T P; Spuhler, V J; Berwick, D M; Nolan, T W

    1998-06-15

    Cooperation--working together to produce mutual benefit or attain a common purpose--is almost inseparable from the quest for improvement. Although the case for cooperation can be made on ethical grounds, neither the motivation for nor the effects of cooperation need to be interpreted solely in terms of altruism. Cooperation can be a shrewd and pragmatic strategy for accomplishing personal goals in an interdependent system. Earlier papers in this series have explored the conceptual roots of modern approaches to improvement, which lie in systems theory. To improve systems, we must usually attend first and foremost to interactions. Among humans, "better interaction" is almost synonymous with "better cooperation." Physicians have ample opportunities and, indeed, an obligation to cooperate with other physicians in the same or different specialties, with nurses and other clinical workers, with administrators, and with patients and families. Many intellectual disciplines have made cooperation an object of study. These include anthropology; social psychology; genetics; biology; mathematics; game theory; linguistics; operations research; economics; and, of course, moral and rational philosophy. Scientifically grounded methods to enhance cooperation include developing a shared purpose; creating an open, safe environment; including all who share a common purpose and encouraging diverse viewpoints; negotiating agreement; and insisting on fairness and equity in the application of rules. These methods apply at the organizational level and at the level of the individual physician. This paper describes the application of these methods at the organizational level and focuses on one especially successful example of system-level cooperation in a care delivery site where interactions matter a great deal: the modern intensive care unit. PMID:9625663

  16. Orthopaedic research and education foundation and industry.

    PubMed

    Wurth, Gene R; Sherr, Judy H; Coffman, Thomas M

    2003-07-01

    Members of orthopaedic industry commit a significant amount of funds each year to support research and education programs that are directly related to their product(s). In addition, industry supports organizations such as the Orthopaedic Research and Education Foundation. The relationship between the Orthopaedic Research and Education Foundation and industry began in the early 1980s. The support to the Orthopaedic Research and Education Foundation from industry primarily has come in the form of unrestricted grants. These grants best can be looked at as an investment rather than a contribution. This form of giving, once called corporate philanthropy is more accurately referred to as strategic philanthropy. Members of industry make these investments to enhance their reputations, build brand awareness, market their products and services, improve employee morale, increase customer loyalty, and establish strategic alliances. The specialty of orthopaedics is among the leaders in medicine in the amount of funding raised within the specialty for research and education programs. This is because of the amount of support from members of industry and the surgeons. During the past 15 years, 40% of the annual support to the Orthopaedic Research and Education Foundation has come from industry and the balance has come from surgeons and members of lay public. Future industry support of the Orthopaedic Research and Education Foundation and other organizations within the specialty of orthopaedics will be dependent on the continued demonstration of tangible returns in areas described. PMID:12838052

  17. Auditory midbrain implant: research and development towards a second clinical trial.

    PubMed

    Lim, Hubert H; Lenarz, Thomas

    2015-04-01

    The cochlear implant is considered one of the most successful neural prostheses to date, which was made possible by visionaries who continued to develop the cochlear implant through multiple technological and clinical challenges. However, patients without a functional auditory nerve or implantable cochlea cannot benefit from a cochlear implant. The focus of the paper is to review the development and translation of a new type of central auditory prosthesis for this group of patients that is known as the auditory midbrain implant (AMI) and is designed for electrical stimulation within the inferior colliculus. The rationale and results for the first AMI clinical study using a multi-site single-shank array will be presented initially. Although the AMI has achieved encouraging results in terms of safety and improvements in lip-reading capabilities and environmental awareness, it has not yet provided sufficient speech perception. Animal and human data will then be presented to show that a two-shank AMI array can potentially improve hearing performance by targeting specific neurons of the inferior colliculus. A new two-shank array, stimulation strategy, and surgical approach are planned for the AMI that are expected to improve hearing performance in the patients who will be implanted in an upcoming clinical trial funded by the National Institutes of Health. Positive outcomes from this clinical trial will motivate new efforts and developments toward improving central auditory prostheses for those who cannot sufficiently benefit from cochlear implants. This article is part of a Special Issue entitled <Lasker Award>. PMID:25613994

  18. The 21st Annual Prostate Cancer Foundation Scientific Retreat report.

    PubMed

    Miyahira, Andrea K; Simons, Jonathan W; Soule, Howard R

    2015-08-01

    The 21st Annual Prostate Cancer Foundation (PCF) Scientific Retreat was held from October 23-25, 2014, in Carlsbad, CA. This event is the world's foremost scientific meeting focusing on prostate cancer and brings together leading basic, translational and clinical researchers in prostate cancer and other diverse disciplines to discuss the newest findings most likely to advance the understanding of prostate cancer and the clinical care of prostate cancer patients. This year's meeting highlighted themes including: (i) research integrity and standards for scientific reproducibility; (ii) prostate cancer disparities; (iii) mechanisms and models of prostate cancer progression and dormancy; (iv) mechanisms of therapeutic resistance; and (v) advancements in precision medicine treatments, treatment models, and predictive and prognostic biomarkers.

  19. Expert Meeting Report. Foundations Research Results

    SciTech Connect

    Ojczyk, C.; Huelman, P.; Carmody, J.

    2013-05-01

    The NorthernSTAR Building America Partnership held an expert meeting on Foundations–Research Results on November 15, 2011, in Minneapolis, MN. Audience participation was actively encouraged during each presentation to uncover needs and promote dialog among researchers and industry professionals. Key results were: greater understanding of the role of moisture transport through foundation and insulation materials and its potential impact on building durability; greater understanding of the role of foundation type in the process of selecting an insulation system for energy performance and building durability; need for research to quantify the risks associated with insulation processes to better enable users to weigh costs and benefits against the existing conditions of a home; need for improved performance modeling capabilities that address variations in foundation types and soil conditions.

  20. Analysis of foundations on reinforced soil

    NASA Astrophysics Data System (ADS)

    Brown, B. S.; Poulos, H. G.

    1980-10-01

    A finite element model of reinforced earth is used to investigate the increase in bearing capacity and stiffness of a foundation due to the placement of reinforcement in the soil. The analysis is used to examine the effect of reinforcement on the load settlement behavior of a strip foundation founded on a c-theta soil. It is shown that the improvement in foundation performance depends on both the number of reinforcing layers and on the concentration (surface area per unit width of footing) of the reinforcement. The case of a footing on a reinforced soil mass overlying a cavity or a very soft zone is also analyzed, and the reinforced soil is shown to result in a significant improvement in footing performance.

  1. Signature Pedagogies for Social Foundations: Negotiating Social Foundations Teaching Practices in the Field of Education

    ERIC Educational Resources Information Center

    Schneider, Sandra B.

    2010-01-01

    The conflicts arising between the pedagogical preferences of the fields of instructional design and technology (IDT) and social foundations of education are substantial. This conflict is primarily one of pedagogical values separating the Social Foundations with its emphasis on critical and creative thinking and the presumption of value and theory…

  2. Foundations for the Future: The Fundraising Role of Foundation Boards at Public Colleges and Universities

    ERIC Educational Resources Information Center

    Worth, Michael

    2012-01-01

    In the face of rising costs and a prolonged economic downturn, public colleges and universities are being challenged to increase their sources of private support and philanthropy. Drawing on the findings of a recent AGB survey of public college- and university-affiliated foundation board chairs and chief executive officers, Foundations for the…

  3. Effective Foundation Boards: A Guide for Members of Institutionally Related Foundation Boards

    ERIC Educational Resources Information Center

    Association of Governing Boards of Universities and Colleges, 2012

    2012-01-01

    Institutionally related foundations are an important partner to all institutions of public higher education. As public colleges, universities, and systems respond to a shifting landscape, related foundations have become increasingly important to their financial sustainability, commitment to academic access and educational excellence, and…

  4. Kellogg Foundation Initiative: Rewriting the Way Foundations Do Business in Indian Country.

    ERIC Educational Resources Information Center

    Boyer, Paul

    2000-01-01

    Describes the multi-million dollar initiative announced by W. K. Kellogg Foundation in 1995 to support the Native American Higher Education Initiative, and how the Kellogg initiative deserves attention from the nation as a whole because it is attempting to fundamentally rewrite the way foundations do business with Indian communities. (VWC)

  5. Philosophical foundations of respect for autonomy.

    PubMed

    Gauthier, C C

    1993-03-01

    Understanding the philosophical foundations of the principle of respect for autonomy is essential for its proper application within medical ethics. The foundations provided by Immanuel Kant's principle of humanity and John Stuart Mill's principle of liberty share substantial areas of agreement including: the grounding of respect for autonomy in the capacity for rational agency, the restriction of this principle to rational agents, and the important distinction between influence and control. Their work helps to clarify the scope and role of the principle of respect for autonomy in health care delivery; its implications for truth telling, informed consent, and confidentiality; and its relationship to other moral principles, such as beneficence and distributive justice.

  6. Peace Education: Exploring Some Philosophical Foundations

    NASA Astrophysics Data System (ADS)

    Page, James S.

    2004-01-01

    Peace education has been recognized as an important aspect of social education for the past three decades. The critical literature as well as official documents, however, have given little attention to its philosophical foundations. This essay explores these foundations in the ethics of (1) virtue, (2) consequentialism, (3) aesthetics, (4) conservative politics and (5) care. Each of these alone composes a significant element of peace education, although ultimately its solid basis can only be established through an integrative approach encouraging a culture of peace. The more complete development and articulation of the philosophical rationale of peace education is yet to be accomplished and remains a task for the future.

  7. 22 CFR 1502.3 - Access to Foundation records.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Access to Foundation records. 1502.3 Section 1502.3 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION AVAILABILITY OF RECORDS § 1502.3 Access to Foundation records. Any person desiring to have access to Foundation records may call or apply in...

  8. 22 CFR 1502.3 - Access to Foundation records.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Access to Foundation records. 1502.3 Section 1502.3 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION AVAILABILITY OF RECORDS § 1502.3 Access to Foundation records. Any person desiring to have access to Foundation records may call or apply in...

  9. 22 CFR 1502.3 - Access to Foundation records.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Access to Foundation records. 1502.3 Section 1502.3 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION AVAILABILITY OF RECORDS § 1502.3 Access to Foundation records. Any person desiring to have access to Foundation records may call or apply in...

  10. 22 CFR 1002.3 - Access to Foundation records.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Access to Foundation records. 1002.3 Section 1002.3 Foreign Relations INTER-AMERICAN FOUNDATION AVAILABILITY OF RECORDS § 1002.3 Access to Foundation records. Any person desiring to have access to Foundation records should call or apply in...

  11. 22 CFR 1002.3 - Access to Foundation records.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Access to Foundation records. 1002.3 Section 1002.3 Foreign Relations INTER-AMERICAN FOUNDATION AVAILABILITY OF RECORDS § 1002.3 Access to Foundation records. Any person desiring to have access to Foundation records should call or apply in...

  12. 22 CFR 1002.3 - Access to Foundation records.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Access to Foundation records. 1002.3 Section 1002.3 Foreign Relations INTER-AMERICAN FOUNDATION AVAILABILITY OF RECORDS § 1002.3 Access to Foundation records. Any person desiring to have access to Foundation records should call or apply in...

  13. 22 CFR 1502.3 - Access to Foundation records.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Access to Foundation records. 1502.3 Section 1502.3 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION AVAILABILITY OF RECORDS § 1502.3 Access to Foundation records. Any person desiring to have access to Foundation records may call or apply in...

  14. 22 CFR 1002.3 - Access to Foundation records.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Access to Foundation records. 1002.3 Section 1002.3 Foreign Relations INTER-AMERICAN FOUNDATION AVAILABILITY OF RECORDS § 1002.3 Access to Foundation records. Any person desiring to have access to Foundation records should call or apply in...

  15. 22 CFR 1002.3 - Access to Foundation records.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Access to Foundation records. 1002.3 Section 1002.3 Foreign Relations INTER-AMERICAN FOUNDATION AVAILABILITY OF RECORDS § 1002.3 Access to Foundation records. Any person desiring to have access to Foundation records should call or apply in...

  16. 22 CFR 1502.3 - Access to Foundation records.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Access to Foundation records. 1502.3 Section 1502.3 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION AVAILABILITY OF RECORDS § 1502.3 Access to Foundation records. Any person desiring to have access to Foundation records may call or apply in...

  17. National Science Foundation Annual Report 1989.

    ERIC Educational Resources Information Center

    National Science Foundation, Washington, DC.

    The report begins with a statement from the National Science Foundation (NSF) director, followed by a series of research notes summarizing research findings and results during the year 1989. Chapter 1, "Research Collaborations," describes some examples of the collaborations between universities, industry, and government in astronomy, atmospheric…

  18. Siemens Foundation and the STEM Challenge

    ERIC Educational Resources Information Center

    Harper-Taylor, Jeniffer

    2010-01-01

    For more than 12 years, the Siemens Foundation has found unique ways to partner with organizations to support educational initiatives in science, technology, engineering and mathematics (STEM) in the United States. Its focus is clear--to educate the next generation of innovators by supporting math and science education from grade school to grad…

  19. Excavationless Exterior Foundation Insulation Field Study

    SciTech Connect

    Schirber, T.; Mosiman, G.; Ojczyk, C.

    2014-10-01

    Building science research supports installing exterior (soil side) foundation insulation as the optimal method to enhance the hygrothermal performance of new homes. With exterior foundation insulation, water management strategies are maximized while insulating the basement space and ensuring a more even temperature at the foundation wall. However, such an approach can be very costly and disruptive when applied to an existing home, requiring deep excavation around the entire house. The NorthernSTAR Building America Partnership team implemented an innovative, minimally invasive foundation insulation upgrade technique on an existing home. The approach consisted of using hydrovac excavation technology combined with a liquid insulating foam. The team was able to excavate a continuous 4" wide by 4' to 5' deep trench around the entire house, 128 linear feet, except for one small part under the stoop that was obstructed with concrete debris. The combination pressure washer and vacuum extraction technology also enabled the elimination of large trenches and soil stockpiles normally produced by backhoe excavation. The resulting trench was filled with liquid insulating foam, which also served as a water-control layer of the assembly. The insulation was brought above grade using a liquid foam/rigid foam hybrid system and terminated at the top of the rim joist. Cost savings over the traditional excavation process ranged from 23% to 50%. The excavationless process could result in even greater savings since replacement of building structures, exterior features, utility meters, and landscaping would be minimal or non-existent in an excavationless process.

  20. Readiness, Behavior, and Foundational Mathematics Course Success

    ERIC Educational Resources Information Center

    Li, Kevin; Zelenka, Richard; Buonaguidi, Larry; Beckman, Robert; Casillas, Alex; Crouse, Jill; Allen, Jeff; Hanson, Mary Ann; Acton, Tara; Robbins, Steve

    2013-01-01

    This study examines the effects of math readiness and student course behavior (e.g., attendance, participation, homework completion) on knowledge gain and course success using two samples of students enrolled in foundational skills (noncredit-bearing) mathematics courses. As hypothesized, entering student mathematics readiness and course behavior…

  1. Social Skills: Laying the Foundation for Success

    ERIC Educational Resources Information Center

    Lynch, Sharon A.; Simpson, Cynthia G.

    2010-01-01

    Well-informed teachers of young children recognize the importance of children's social development. The development of social skills lays a critical foundation for later academic achievement as well as work-related skills. Social development is such a key issue with young children that a number of methods to address social skills have been…

  2. Foundation: Transforming data bases into knowledge bases

    NASA Technical Reports Server (NTRS)

    Purves, R. B.; Carnes, James R.; Cutts, Dannie E.

    1987-01-01

    One approach to transforming information stored in relational data bases into knowledge based representations and back again is described. This system, called Foundation, allows knowledge bases to take advantage of vast amounts of pre-existing data. A benefit of this approach is inspection, and even population, of data bases through an intelligent knowledge-based front-end.

  3. Pavlov and the foundation of behavior therapy.

    PubMed

    Plaud, Joseph J

    2003-11-01

    The foundation, achievements, and proliferation of behavior therapy have largely been fueled by the movement's foundation in behavioral principles and theories. Although behavioral accounts of the genesis and treatment of psychopathology differ in the extent to which they emphasize classical or operant conditioning, the mediation of cognitive factors, and the role of biological variables, Pavlov's discovery of conditioning principles was essential to the founding of behavior therapy in the 1950s, and continues to be central to modern behavior therapy. Pavlov's reliance on a physiological model of the nervous system, sensible in the context of an early science of neurology, has had an implication for behavior therapists interested in the study of personality types. However, Pavlov's major legacy to behavior therapy was his discovery of "experimental neuroses," shown by his students Eroféeva and Shenger-Krestovnikova, to be produced and eliminated through the principles of conditioning and counter-conditioning. This discovery laid the foundation for the first empirically-validated behavior therapy procedure, systematic desensitization, pioneered by Wolpe. The Pavlovian origins of behavior therapy are analyzed in this paper, and the relevance of conditioning principles to modern behavior therapy is demonstrated. It is shown that Pavlovian conditioning represents far more than a systematic basic learning paradigm. It is also an essential theoretical foundation for the theory and practice of behavior therapy. PMID:14628701

  4. Plain English: The Language of Foundations.

    ERIC Educational Resources Information Center

    McGuire, Betty E.

    1981-01-01

    Since hundreds of requests for grants appear at the offices of American foundations, a proposal that wastes an opportunity by making a poor case cannot be tolerated. Suggestions are given for beginning the grant-writing, drafting the proposal, and avoiding certain problem approaches. (Author/MSE)

  5. The Emotional Foundations of Social Understanding

    ERIC Educational Resources Information Center

    Warren, Heather K.; Denham, Susanne A.; Bassett, Hideko H.

    2008-01-01

    The infant and toddler years are a watershed of development in the emotional domain. These skills lay the foundation for positive social interactions, and ultimately, academic and life success. This article describes the development of three skills that are central in creating successful relationships: expressing emotion, understanding emotion,…

  6. Theoretical Foundations for Website Design Courses.

    ERIC Educational Resources Information Center

    Walker, Kristin

    2002-01-01

    Considers how theoretical foundations in website design courses can facilitate students learning the genres of Internet communication. Proposes ways that theories can be integrated into website design courses. Focuses on two students' website portfolios and ways they utilize genre theory and activity theory discussed in class to produce websites…

  7. Foundation for the Future: Turning Points.

    ERIC Educational Resources Information Center

    National Science Foundation, Arlington, VA. Directorate for Education and Human Resources.

    This booklet, the third publication in the Foundation for the Future series, illustrates how involvement in the Directorate for Education and Human Resources' (EHR's) projects has been a watershed for many people. The personal profiles contained within describe how EHR programs are: changing people's lives, opening people's minds to new…

  8. The Philosophical Foundations of Lifelong Learning.

    ERIC Educational Resources Information Center

    Michopoulos, Aristotle

    The current lifelong learning movement, the new force toward global education, owes much to the League of Nations and the United Nations that sponsored an expanded multiracial "polis." Its philosophical foundations go back, however, to ancient China, India, and especially Greece, where philosophers and scientists got their creative stimulus from…

  9. Philosophical Foundations of Adult Education. Second Edition.

    ERIC Educational Resources Information Center

    Elias, John L.; Merriam, Sharan B.

    This book examines the philosophical foundations of adult education (AE). The following topics are discussed: philosophy of AE (philosophy and action in theory and practice and philosophy for adult educators); liberal AE (historical development, liberal education and the educated person, broad scope, process, liberal education of adults, Great…

  10. Fundraising in Community College Foundations. ERIC Digest.

    ERIC Educational Resources Information Center

    Schuyler, Gwyer

    In response to declining local and state appropriations for public education, community colleges have taken steps to formalize fundraising efforts by creating institutional foundations as recipients of tax-deductible contributions. Large-scale external fundraising at community colleges began as a result of the 1965 Higher Education Act and the…

  11. National Science Foundation Annual Report 1976.

    ERIC Educational Resources Information Center

    National Science Foundation, Washington, DC.

    This document provides highlights of research efforts supported by the National Science Foundation (NSF) in the areas of mathematics, physical sciences, and engineering; astronomical, atmospheric, earth, and ocean sciences; science education; research applied to national needs; and scientific, technological, and international affairs for fiscal…

  12. National Science Foundation Annual Report 1979.

    ERIC Educational Resources Information Center

    National Science Foundation, Washington, DC.

    Presented are highlights of research efforts supported by the National Science Foundation (NSF) in the areas of mathematical and physical sciences; astronomical, atmospheric, earth, and ocean sciences; biological, behavioral, and social sciences; science education; engineering and applied science; and scientific, technological, and international…

  13. Theoretical Foundations of Rorschach by Piotrowski.

    ERIC Educational Resources Information Center

    Daly, William C.

    2005-01-01

    The writer has tried to lift the veil of mystery from the Rorschach Cards by uncovering in simple form the ten basic principles of Zygmunt Protrowski which can be considered the foundation stones of Rorschach; they are composed of psycho-justifications as well as meaningful administrative procedures allowing the reader broader understanding of…

  14. Bernard van Leer Foundation Newsletter, 1996.

    ERIC Educational Resources Information Center

    Bernard van Leer Foundation, Newsletter, 1996

    1996-01-01

    This document consists of the four issues of the Bernard van Leer Foundation's "Newsletter" published during 1996. The newsletter covers topics related to, or about efforts to foster, the education and welfare of children around the world, and includes descriptions of programs around the world, lists of resources and publications, and early…

  15. Research and the Bernard van Leer Foundation.

    ERIC Educational Resources Information Center

    Wall, W. D.

    1978-01-01

    Outlines Bernard van Leer Foundation sponsorship of action programs and research studies of child development in 25 countries. The problems and possibilities of such work are discussed from the viewpoint of evaluation and the contribution which can be made to the behavioral sciences--notably to comparative child development. (Author/RH)

  16. The Joyce Foundation 2011 Annual Report

    ERIC Educational Resources Information Center

    O'Connell, Mary

    2012-01-01

    In a period such as this, marked by extreme political partisanship and apparent gridlock at the federal level, it would be tempting to throw up one's hands in frustration. But this is just the time that a foundation like Joyce can add the most value--because the Joyce team members are non-partisan, not subject to the pressures of political and…

  17. Excavationless Exterior Foundation Insulation Field Study

    SciTech Connect

    Schirber, T.; Mosiman, G.; Ojczyk, C.

    2014-09-01

    Building science research supports installing exterior (soil side) foundation insulation as the optimal method to enhance the hygrothermal performance of new homes. With exterior foundation insulation, water management strategies are maximized while insulating the basement space and ensuring a more even temperature at the foundation wall. However, such an approach can be very costly and disruptive when applied to an existing home, requiring deep excavation around the entire house. The NorthernSTAR Building America Partnership team implemented an innovative, minimally invasive foundation insulation upgrade technique on an existing home. The approach consisted of using hydrovac excavation technology combined with liquid insulating foam. The team was able to excavate a continuous 4 inches wide by 4 feet to 5 feet deep trench around the entire house, 128 linear feet, except for one small part under the stoop that was obstructed with concrete debris. The combination pressure washer and vacuum extraction technology also enabled the elimination of large trenches and soil stockpiles normally produced by backhoe excavation. The resulting trench was filled with liquid insulating foam, which also served as a water-control layer of the assembly. The insulation was brought above grade using a liquid foam/rigid foam hybrid system and terminated at the top of the rim joist. Cost savings over the traditional excavation process ranged from 23% to 50%. The excavationless process could result in even greater savings since replacement of building structures, exterior features, utility meters, and landscaping would be minimal or non-existent in an excavationless process.

  18. Aboriginal Healing Foundation Annual Report, 2001.

    ERIC Educational Resources Information Center

    Aboriginal Healing Foundation, Ottawa (Ontario).

    The Aboriginal Healing Foundation (AHF) is a nonprofit organization established in 1998 with funding from the Canadian Government. Its mission is to support Aboriginal people in building sustainable healing processes that address the legacy of physical and sexual abuse in the residential school system, including intergenerational impacts. AHF…

  19. Foundations for Policy in Guidance and Counseling.

    ERIC Educational Resources Information Center

    Herr, Edwin L., Ed.; Pinson, Nancy M., Ed.

    This book provides educators, counselors, policy makers, and community members with information about the state of the art of federal and state policy in guidance and counseling. The two chapters in part 1, Overview, are: "Foundations for Policy in Guidance and Counseling: An Introduction", by Edwin L. Herr and Nancy M. Pinson; and "A Counselor…

  20. FELS FOUNDATION PROJECT FOR DEVELOPING YOUTH POTENTIAL.

    ERIC Educational Resources Information Center

    BAIR, ROBERT A.; AND OTHERS

    THE OPERATION OF THE FELS FOUNDATION PROJECT FOR DEVELOPING YOUTH POTENTIAL IN HANFORD, CALIFORNIA, IS DESCRIBED. OF GENERAL CONCERN WAS THE PREPARATION OF CULTURALLY DEPRIVED CHILDREN FOR SCHOOL EXPERIENCES AND FOR FUTURE EMPLOYMENT. A MAJOR GOAL WAS TO IMPROVE THE SELF-IMAGE OF THE CHILDREN AND TO ASSIST THE PARENTS AND CHILDREN IN PROVIDING…

  1. Corner Office Interview: Gates Foundation's Deborah Jacobs

    ERIC Educational Resources Information Center

    Miller, Rebecca

    2010-01-01

    U.S. libraries gave the world a top talent when Deborah Jacobs left her transformational role as City Librarian of Seattle in 2008 to head the Bill & Melinda Gates Foundation's Global Libraries program, the international sibling to the U.S. Libraries program. The initiative fosters national-scale projects with grantees in transitioning countries…

  2. Foundations for Effective School Library Media Programs.

    ERIC Educational Resources Information Center

    Haycock, Ken, Ed.

    This collection of 38 articles, reprinted from "Emergency Librarian," addresses critical elements of school library media program development and implementation, organized by seven areas: foundations; the school context; role clarification; information literacy; collaborative program planning and teaching; program development; and accountability.…

  3. Theoretical Foundations of Learning Environments. Second Edition

    ERIC Educational Resources Information Center

    Jonassen, David, Ed.; Land, Susan, Ed.

    2012-01-01

    "Theoretical Foundations of Learning Environments" provides students, faculty, and instructional designers with a clear, concise introduction to the major pedagogical and psychological theories and their implications for the design of new learning environments for schools, universities, or corporations. Leading experts describe the most important…

  4. The National Science Foundation: A Brief History.

    ERIC Educational Resources Information Center

    National Science Foundation, Washington, DC.

    On May 10, 1950, President Truman signed the bill creating the National Science Foundation (NSF). The act provided for a National Science Board to be created and the law directed the agency to encourage and develop a national policy for the promotion of basic research and education in the mathematical, physical, medical, biological, engineering,…

  5. Online Assessment and Measurement: Foundations and Challenges

    ERIC Educational Resources Information Center

    Hricko, Mary; Howell, Scott

    2006-01-01

    Online learning is one of the most important topics in distance learning, but practitioners and researchers have experienced difficulty in defining the process. "Online Assessment and Measurement: Foundations and Challenges" approaches the topic by finding a common ground to properly analyze online assessment and measurement. "Online Assessment…

  6. Foundational Academic Development: Building Collegiality across Divides?

    ERIC Educational Resources Information Center

    Clarke, Catherine; Reid, Jacqueline

    2013-01-01

    There is limited research into the effectiveness of non-accredited foundational courses for new academic staff. An ongoing issue is that of attention and anxiety overload in the critical first period of employment when the challenges of establishing oneself in a new collegial environment are most acute. Approaches to addressing this issue may be…

  7. Sound Foundations. What Works Clearinghouse Intervention Report

    ERIC Educational Resources Information Center

    What Works Clearinghouse, 2006

    2006-01-01

    "Sound Foundations," a literacy curriculum designed to teach phonological awareness to preliterate children, focuses exclusively on phoneme identity (that is, different words can start and end with the same sound). It works from the principle that phonemic awareness is necessary but not sufficient to reading, which depends on the alphabetic…

  8. Deriving a Pedagogy of Educational Foundations

    ERIC Educational Resources Information Center

    Fenstermacher, Gary D.

    2007-01-01

    This sixth and last paper in the series describes four elements believed to be crucial to a high quality pedagogy for educational foundations. These four elements are derived from a close reading of the previous papers. The work of Osguthorpe, Sanger, Haniford, and Mucher, four of the authors in this series, is cited as both a source for these…

  9. Cultural Foundations of Education. Second Edition.

    ERIC Educational Resources Information Center

    Pai, Young; Adler, Susan A.

    This book is designed to provide educators and prospective educators with knowledge essential to making decisions about teaching and learning. The book is intended as a foundation for thinking about curriculum and pedagogy. Case studies involving African American, Asian American, Hispanic American, Native American, and white American groups are…

  10. The Promises of Moral Foundations Theory

    ERIC Educational Resources Information Center

    Musschenga, Bert

    2013-01-01

    In this article I examine whether Moral Foundations Theory can fulfil the promises that Haidt claims for the theory: that it will help in developing new approaches to moral education and to the moral conflicts that divide our diverse society. I argue that, first, the model that Haidt suggests for understanding the plurality of moralities--a shared…

  11. Foundation literacy acquisition in European orthographies.

    PubMed

    Seymour, Philip H K; Aro, Mikko; Erskine, Jane M

    2003-05-01

    Several previous studies have suggested that basic decoding skills may develop less effectively in English than in some other European orthographies. The origins of this effect in the early (foundation) phase of reading acquisition are investigated through assessments of letter knowledge, familiar word reading, and simple nonword reading in English and 12 other orthographies. The results confirm that children from a majority of European countries become accurate and fluent in foundation level reading before the end of the first school year. There are some exceptions, notably in French, Portuguese, Danish, and, particularly, in English. The effects appear not to be attributable to differences in age of starting or letter knowledge. It is argued that fundamental linguistic differences in syllabic complexity and orthographic depth are responsible. Syllabic complexity selectively affects decoding, whereas orthographic depth affects both word reading and nonword reading. The rate of development in English is more than twice as slow as in the shallow orthographies. It is hypothesized that the deeper orthographies induce the implementation of a dual (logographic + alphabetic) foundation which takes more than twice as long to establish as the single foundation required for the learning of a shallow orthography.

  12. Western European Art Foundations and Publishing

    ERIC Educational Resources Information Center

    King, Lindsay M.; Clement, Russell T.

    2011-01-01

    Western European art foundations create invaluable opportunities for research and exhibition by artists, curators, and scholars. These activities are often documented and disseminated via high-quality publications. This article highlights an important but under-recognized collecting resource for academic and museum libraries by profiling several…

  13. Excavations and Foundations in Soft Soils

    NASA Astrophysics Data System (ADS)

    Kempfert, Hans-Georg; Gebreselassie, Berhane

    The book reviews the experiences with, as well as recent developments and research results on excavations and foundations in and on soft soil deposits. Geotechnical design and execution of civil engineering structures on very soft soils are usually associated with substantial difficulties.

  14. The TRY Foundation: A Case Study in Private Community Development Organizations.

    ERIC Educational Resources Information Center

    McClure, Paul T.

    This is a case study of the TRY Foundation, a privately funded non-profit corporation devoting its resources to "community and human development in disadvantaged areas." Activities sponsored by its primate unit, the Willowbrook Chapter of Watts, Los Angeles, include: thrift shop, preventive dentistry clinic, Operation Vegetable Basket--which…

  15. A critical examination of the foundations of immunotherapy for cancer.

    PubMed

    Hewitt, H B

    1979-07-01

    It is argued that immunotherapy (IMTH) for cancer, as well as the theory of cancer immunogenicity on which it rests, derives no secure foundation either from clinical observations or from experimental study of valid animal tumour models. Discouraging clinical observations include: the long history of failure of IMTH; the rejection of IMTH for choriocarcinoma--a true allograft in the patient; the extreme rarity of spontaneous regression, and progressive discrediting of the theory of immunosurveillance; the high frequency of nodal metastasis; and the failure to demonstrate a tumour-specific antigen in man. The great majority of animal tumours used for experimental studies of IMTH display artefactual immunogenicity associated with their mode of induction or conditions of transplantation and cannot be accepted as valid models of clinical cancer. The author reviews his total failure to demonstrate immunogenicity or successful IMTH using a wide range of animal tumours from which known laboratory artefacts have been strictly excluded. The inordinate promotion of tumour immunology and IMTH in recent years is attributed to unfortunate sociological influences encouraging premature assertion of clinical relevance from experimental research. PMID:572751

  16. SUSTAINABLE CONCRETE FOR WIND TURBINE FOUNDATIONS.

    SciTech Connect

    BERNDT,M.L.

    2004-06-01

    The use of wind power to generate electricity continues to grow, especially given commitments by various countries throughout the world to ensure that a significant percentage of energy comes from renewable sources. In order to meet such objectives, increasingly larger turbines with higher capacity are being developed. The engineering aspects of larger turbine development tend to focus on design and materials for blades and towers. However, foundations are also a critical component of large wind turbines and represent a significant cost of wind energy projects. Ongoing wind research at BNL is examining two areas: (a) structural response analysis of wind turbine-tower-foundation systems and (b) materials engineering of foundations. This work is investigating the dynamic interactions in wind turbine systems, which in turn assists the wind industry in achieving improved reliability and more cost efficient foundation designs. The results reported herein cover initial studies of concrete mix designs for large wind turbine foundations and how these may be tailored to reduce cost and incorporate sustainability and life cycle concepts. The approach taken was to investigate material substitutions so that the environmental, energy and CO{sub 2}-impact of concrete could be reduced. The use of high volumes of ''waste'' materials in concrete was examined. These materials included fly ash, blast furnace slag and recycled concrete aggregate. In addition, the use of steel fiber reinforcement as a means to improve mechanical properties and potentially reduce the amount of bar reinforcement in concrete foundations was studied. Four basic mixes were considered. These were: (1) conventional mix with no material substitutions, (2) 50% replacement of cement with fly ash, (3) 50% replacement of cement with blast furnace slag and (4) 25% replacement of cement with fly ash and 25% replacement with blast furnace slag. Variations on these mixes included the addition of 1% by volume steel

  17. Authenticity as a foundational principle of medical ethics.

    PubMed

    Welie, J V

    1994-01-01

    Increasingly, contemporary medical ethicists have become aware of the need to explicate a foundation for their various models of applied ethics. Many of these theories are inspired by the apparent incompatibility of patient autonomy and provider beneficence. The principle of patient autonomy derives its current primacy to a large extent from its legal origins. However, this principle seems at odds with the clinical reality. In the bioethical literature, the notion of authenticity has been proposed as an alternative foundational principle to autonomy. This article examines this proposal in reference to various existentialist philosophers (Heidegger, Sartre, Camus and Marcel). It is concluded that the principle of autonomy fails to do what it is commonly supposed to do: provide a criterion of distinction that can be invoked to settle moral controversies between patients and providers. The existentialist concept of authenticity is more promising in at least one crucial respect: It acknowledges that the essence of human life disappears from sight if life's temporal character is reduced to a series of present decisions and actions. This also implies that the very quest for a criterion that allows physicians to distinguish between sudden, unexpected decisions of their patients to be or not to be respected, without recourse to the patient's past or future, is erroneous.

  18. Can Innate, modular "foundations" explain morality? Challenges for Haidt's Moral Foundations Theory.

    PubMed

    Suhler, Christopher L; Churchland, Patricia

    2011-09-01

    Jonathan Haidt's Moral Foundations Theory is an influential scientific account of morality incorporating psychological, developmental, and evolutionary perspectives. The theory proposes that morality is built upon five innate "foundations," each of which is believed to have been selected for during human evolution and, subsequently, tuned-up by learning during development. We argue here that although some general elements of Haidt's theory are plausible, many other important aspects of his account are seriously flawed. First, innateness and modularity figure centrally in Haidt's account, but terminological and conceptual problems foster confusion and ambiguities. Second, both the theory's proposed number of moral foundations and its taxonomy of the moral domain appear contrived, ignoring equally good candidate foundations and the possibility of substantial intergroup differences in the foundations' contents. Third, the mechanisms (viz., modules) and categorical distinctions (viz., between foundations) proposed by the theory are not consilient with discoveries in contemporary neuroscience concerning the organization, functioning, and development of the brain. In light of these difficulties, we suggest that Haidt's theory is inadequate as a scientific account of morality. Nevertheless, the theory's weaknesses are instructive, and hence, criticism may be useful to psychologists, neuroscientists, and philosophers attempting to advance theories of morality, as well as to researchers wishing to invoke concepts such as innateness and modularity more generally.

  19. Technique in Cleft Rhinoplasty: The Foundation Graft.

    PubMed

    Gassner, Holger G; Schwan, Franziska; Haubner, Frank; Suárez, Gustavo A; Vielsmeier, Veronika

    2016-04-01

    Secondary cleft rhinoplasty represents a particular surgical challenge. The authors have identified the deficit in skeletal projection of the cleft-sided piriform rim as an important contributor to the pathology. A graft is described to augment the piriform crest on the cleft side. This foundation graft is suture fixated to the piriform crest after complete release of all soft tissue attachments to the alar base. The foundation graft is articulated with a long alar strut graft, which allows for powerful projection of the cleft-sided nasal tip. An advancement flap of vestibular skin is described to correct the vestibular stenosis. A transplant of diced cartilage in fascia is added to augment maxillary soft tissue volume. Subjective and objective measures of form and function are presented in a retrospective series of five cases, illustrating the efficacy of the techniques described. PMID:27097143

  20. Excavationless Exterior Foundation Insulation Exploratory Study

    SciTech Connect

    Mosimann, Garrett; Wagner, Rachel; Schirber, Tom

    2013-02-01

    The key objective of this exploratory study was to investigate the feasibility of the development or adoption of technologies that would enable a large percentage of existing homes in cold climates to apply a combination 'excavationless' soil removal process with appropriate insulation and water management on the exterior of existing foundations at a low cost. Our approach was to explore existing excavation and material technologies and systems to discover whether potential successful combinations existed.

  1. Foundation Trusts: economics in the 'postmodern hospital'.

    PubMed

    Newbold, David

    2005-09-01

    Foundation Trust Hospitals are community-controlled health care providers which have increased autonomy about how they produce outcomes for the British National Health Service. Although there is a literature on hospital economics it is unclear how these innovative providers will behave, if they have to compete for scarce resources with other hospitals. This paper reviews some of the earlier theories, such as the neoclassical theory of the firm, and discusses their relevance along with 'newer' economic theories such as the transaction costs and evolutionary theory of the firm, plus organizational and human resources theory, to the performance of Foundation Trusts. Much contemporary health care provision is shaped along modernist lines, using scientific endeavour to maximize the impact on health outcomes and technical and social efficiency. However, there is an increasingly postmodern standpoint--critical of modernity--being taken by both patients and hospital staff, to deconstruct processes in the organizations that serve them. Foundation Trusts are postmodern hospitals insomuch as they (to attract scarce resources in a competitive environment), need to marshal the diverse theories of the firm together in order to provide a mass-customized, quality experience, transparently and at least cost--whilst maintaining a stable organizational culture for staff.

  2. International Foundation for Functional Gastrointestinal Disorders

    MedlinePlus

    ... Corner Clinical Corner Survey Corner News News Events Press Releases Commentary For Media Research Research Awards Research Grants ... Corner Clinical Corner Survey Corner News News Events Press Releases Commentary For Media Research Research Awards Research Grants ...

  3. Public health and nutrition after the Spanish Civil War. An intervention by the Rockefeller Foundation.

    PubMed

    Del Cura, Isabel; Huertas, Rafael

    2009-10-01

    We describe a nutritional intervention by the Rockefeller Foundation's International Health Division in Spain after the Spanish Civil War, delineating the relationships between the technicians sent by the Rockefeller Foundation and the Spanish health authorities. We analyze reports of the nutritional situation in Spain in the early 1940s and the design and outcomes of a nutrition survey conducted in a district of Madrid by American and Spanish nutritionists. This nutritional survey, which was based on food intake interviews and was complemented with anthropometric measurements, clinical examinations, and blood tests, found several symptoms and signs of malnutrition. The Rockefeller Foundation's nutritional research was an important historical precedent for later studies made in emergency situations or armed conflicts. Similar surveys have been carried out in the last several decades by distinguished academic departments of public health and epidemiology and by humanitarian aid agencies.

  4. Public Health and Nutrition After the SPANISH CIVIL WAR An Intervention by the Rockefeller Foundation

    PubMed Central

    del Cura, Isabel

    2009-01-01

    We describe a nutritional intervention by the Rockefeller Foundation's International Health Division in Spain after the Spanish Civil War, delineating the relationships between the technicians sent by the Rockefeller Foundation and the Spanish health authorities. We analyze reports of the nutritional situation in Spain in the early 1940s and the design and outcomes of a nutrition survey conducted in a district of Madrid by American and Spanish nutritionists. This nutritional survey, which was based on food intake interviews and was complemented with anthropometric measurements, clinical examinations, and blood tests, found several symptoms and signs of malnutrition. The Rockefeller Foundation's nutritional research was an important historical precedent for later studies made in emergency situations or armed conflicts. Similar surveys have been carried out in the last several decades by distinguished academic departments of public health and epidemiology and by humanitarian aid agencies. PMID:19696398

  5. The Role of Community College Trustees in Supporting the Foundation

    ERIC Educational Resources Information Center

    Nielsen, Norm; Newton, Wayne; Mitvalsky, Cheryle W.

    2003-01-01

    The role of the institutional trustees in supporting foundation efforts is explored. Four priorities are described: projecting a positive image for the college, overseeing and maintaining an institutional structure that supports the foundation, sustaining an engaged administration, and encouraging innovation.

  6. IET. Exhaust stack foundation under construction. Reinforced concrete footings for ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    IET. Exhaust stack foundation under construction. Reinforced concrete footings for duct at right of stack. Foundation is in octagonal shape. Date: October 29, 1954. INEEL negative no. 12711 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

  7. 14. FLOODED POWER HOUSE FOUNDATION EXCAVATION BEING PUMPED OUT. NOTE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. FLOODED POWER HOUSE FOUNDATION EXCAVATION BEING PUMPED OUT. NOTE KEYS IN FOREBAY ABUTMENT TO INTERLOCK WITH POWER HOUSE FOUNDATION, March 1918. - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  8. Boot Camp for Education CEOs: The Broad Foundation Superintendents Academy

    ERIC Educational Resources Information Center

    Jehlen, Alain

    2012-01-01

    The Broad Foundation Superintendents Academy is the most prominent and most controversial training institute for school chiefs. The Academy is the flagship program of the Eli and Edythe Broad Foundation, the smallest of a triumvirate of corporate foundations that are at the heart of the billionaire campaign to remake public education in the image…

  9. 26 CFR 1.507-3 - Special rules; transferee foundations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 7 2011-04-01 2009-04-01 true Special rules; transferee foundations. 1.507-3... TAX (CONTINUED) INCOME TAXES (CONTINUED) Private Foundations § 1.507-3 Special rules; transferee foundations. (a) General rule. (1) For purposes of part II, subchapter F, chapter 1 of the Code, in the...

  10. 26 CFR 1.507-3 - Special rules; transferee foundations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Special rules; transferee foundations. 1.507-3... TAX (CONTINUED) INCOME TAXES (CONTINUED) Private Foundations § 1.507-3 Special rules; transferee foundations. (a) General rule. (1) For purposes of part II, subchapter F, chapter 1 of the Code, in the...

  11. 26 CFR 1.507-3 - Special rules; transferee foundations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 7 2013-04-01 2013-04-01 false Special rules; transferee foundations. 1.507-3... TAX (CONTINUED) INCOME TAXES (CONTINUED) Private Foundations § 1.507-3 Special rules; transferee foundations. (a) General rule. (1) For purposes of part II, subchapter F, chapter 1 of the Code, in the...

  12. 26 CFR 1.507-3 - Special rules; transferee foundations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 7 2012-04-01 2012-04-01 false Special rules; transferee foundations. 1.507-3... TAX (CONTINUED) INCOME TAXES (CONTINUED) Private Foundations § 1.507-3 Special rules; transferee foundations. (a) General rule. (1) For purposes of part II, subchapter F, chapter 1 of the Code, in the...

  13. 45 CFR 650.2 - National Science Foundation patent policy.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false National Science Foundation patent policy. 650.2 Section 650.2 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION PATENTS § 650.2 National Science Foundation patent policy. As authorized by the National...

  14. 45 CFR 650.2 - National Science Foundation patent policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false National Science Foundation patent policy. 650.2 Section 650.2 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION PATENTS § 650.2 National Science Foundation patent policy. As authorized by the National...

  15. 45 CFR 650.2 - National Science Foundation patent policy.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 3 2012-10-01 2012-10-01 false National Science Foundation patent policy. 650.2... FOUNDATION PATENTS § 650.2 National Science Foundation patent policy. As authorized by the National Science... adopted the following statement of NSF patent policy. (a) In accordance with the Bayh-Dole Act and...

  16. 45 CFR 650.2 - National Science Foundation patent policy.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false National Science Foundation patent policy. 650.2... FOUNDATION PATENTS § 650.2 National Science Foundation patent policy. As authorized by the National Science... adopted the following statement of NSF patent policy. (a) In accordance with the Bayh-Dole Act and...

  17. 45 CFR 650.2 - National Science Foundation patent policy.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false National Science Foundation patent policy. 650.2... FOUNDATION PATENTS § 650.2 National Science Foundation patent policy. As authorized by the National Science... adopted the following statement of NSF patent policy. (a) In accordance with the Bayh-Dole Act and...

  18. Foundational model of neuroanatomy: implications for the Human Brain Project.

    PubMed Central

    Martin, R. F.; Mejino, J. L.; Bowden, D. M.; Brinkley, J. F.; Rosse, C.

    2001-01-01

    In order to meet the need for a controlled terminology in neuroinformatics, we have integrated the extensive terminology of NeuroNames into the Foundational Model of anatomy. We illustrate the application of foundational principles for the establishment of an inheritance hierarchy, which accommodates anatomical attributes of neuroanatomical concepts and provides the foundation to which other information may be linked. PMID:11825226

  19. 26 CFR 1.642(c)-4 - Nonexempt private foundations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 8 2013-04-01 2013-04-01 false Nonexempt private foundations. 1.642(c)-4... private foundations. In the case of a trust which is, or is treated under section 4947(a)(1) as though it were, a private foundation (as defined in section 509(a) and the regulations thereunder) that is...

  20. 22 CFR 1002.5 - Records available at the Foundation.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Records available at the Foundation. 1002.5 Section 1002.5 Foreign Relations INTER-AMERICAN FOUNDATION AVAILABILITY OF RECORDS § 1002.5 Records available at the Foundation. The General Counsel's Office will make available, to the extent not...

  1. 45 CFR 1100.7 - Foundation report of actions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Foundation report of actions. 1100.7 Section 1100.7 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL FOUNDATION ON THE ARTS... AVAILABILITY OF INFORMATION § 1100.7 Foundation report of actions. On or before March 1 of each calendar...

  2. 22 CFR 1002.5 - Records available at the Foundation.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Records available at the Foundation. 1002.5 Section 1002.5 Foreign Relations INTER-AMERICAN FOUNDATION AVAILABILITY OF RECORDS § 1002.5 Records available at the Foundation. The General Counsel's Office will make available, to the extent not...

  3. 22 CFR 1002.5 - Records available at the Foundation.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Records available at the Foundation. 1002.5 Section 1002.5 Foreign Relations INTER-AMERICAN FOUNDATION AVAILABILITY OF RECORDS § 1002.5 Records available at the Foundation. The General Counsel's Office will make available, to the extent not...

  4. 22 CFR 1502.5 - Records available at the Foundation.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Records available at the Foundation. 1502.5 Section 1502.5 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION AVAILABILITY OF RECORDS § 1502.5 Records available at the Foundation. The Administration and Finance Division will make available for...

  5. 22 CFR 1502.5 - Records available at the Foundation.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Records available at the Foundation. 1502.5 Section 1502.5 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION AVAILABILITY OF RECORDS § 1502.5 Records available at the Foundation. The Administration and Finance Division will make available for...

  6. 26 CFR 1.642(c)-4 - Nonexempt private foundations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 8 2012-04-01 2012-04-01 false Nonexempt private foundations. 1.642(c)-4... private foundations. In the case of a trust which is, or is treated under section 4947(a)(1) as though it were, a private foundation (as defined in section 509(a) and the regulations thereunder) that is...

  7. 45 CFR 1100.7 - Foundation report of actions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Foundation report of actions. 1100.7 Section 1100.7 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL FOUNDATION ON THE ARTS... AVAILABILITY OF INFORMATION § 1100.7 Foundation report of actions. On or before March 1 of each calendar...

  8. 26 CFR 1.642(c)-4 - Nonexempt private foundations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 8 2014-04-01 2014-04-01 false Nonexempt private foundations. 1.642(c)-4... private foundations. In the case of a trust which is, or is treated under section 4947(a)(1) as though it were, a private foundation (as defined in section 509(a) and the regulations thereunder) that is...

  9. 45 CFR 1100.7 - Foundation report of actions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Foundation report of actions. 1100.7 Section 1100.7 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL FOUNDATION ON THE ARTS... AVAILABILITY OF INFORMATION § 1100.7 Foundation report of actions. On or before March 1 of each calendar...

  10. 26 CFR 1.642(c)-4 - Nonexempt private foundations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Nonexempt private foundations. 1.642(c)-4... foundations. In the case of a trust which is, or is treated under section 4947(a)(1) as though it were, a private foundation (as defined in section 509(a) and the regulations thereunder) that is not exempt...

  11. 45 CFR 1100.7 - Foundation report of actions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 3 2012-10-01 2012-10-01 false Foundation report of actions. 1100.7 Section 1100.7 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL FOUNDATION ON THE ARTS... AVAILABILITY OF INFORMATION § 1100.7 Foundation report of actions. On or before March 1 of each calendar...

  12. 22 CFR 1002.5 - Records available at the Foundation.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Records available at the Foundation. 1002.5 Section 1002.5 Foreign Relations INTER-AMERICAN FOUNDATION AVAILABILITY OF RECORDS § 1002.5 Records available at the Foundation. The General Counsel's Office will make available, to the extent not...

  13. 26 CFR 1.507-3 - Special rules; transferee foundations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 7 2014-04-01 2013-04-01 true Special rules; transferee foundations. 1.507-3... TAX (CONTINUED) INCOME TAXES (CONTINUED) Private Foundations § 1.507-3 Special rules; transferee foundations. (a) General rule. (1) For purposes of part II, subchapter F, chapter 1 of the Code, in the...

  14. 45 CFR 1100.7 - Foundation report of actions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Foundation report of actions. 1100.7 Section 1100.7 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL FOUNDATION ON THE ARTS... AVAILABILITY OF INFORMATION § 1100.7 Foundation report of actions. On or before March 1 of each calendar...

  15. 22 CFR 1502.5 - Records available at the Foundation.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Records available at the Foundation. 1502.5 Section 1502.5 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION AVAILABILITY OF RECORDS § 1502.5 Records available at the Foundation. The Administration and Finance Division will make available for...

  16. 22 CFR 1502.5 - Records available at the Foundation.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Records available at the Foundation. 1502.5 Section 1502.5 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION AVAILABILITY OF RECORDS § 1502.5 Records available at the Foundation. The Administration and Finance Division will make available for...

  17. 22 CFR 1002.5 - Records available at the Foundation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Records available at the Foundation. 1002.5 Section 1002.5 Foreign Relations INTER-AMERICAN FOUNDATION AVAILABILITY OF RECORDS § 1002.5 Records available at the Foundation. The General Counsel's Office will make available, to the extent not...

  18. 22 CFR 1502.5 - Records available at the Foundation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Records available at the Foundation. 1502.5 Section 1502.5 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION AVAILABILITY OF RECORDS § 1502.5 Records available at the Foundation. The Administration and Finance Division will make available for...

  19. 26 CFR 1.642(c)-4 - Nonexempt private foundations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 8 2011-04-01 2011-04-01 false Nonexempt private foundations. 1.642(c)-4... private foundations. In the case of a trust which is, or is treated under section 4947(a)(1) as though it were, a private foundation (as defined in section 509(a) and the regulations thereunder) that is...

  20. "We Are Family": Maori Success in Foundation Programmes

    ERIC Educational Resources Information Center

    McMurchy-Pilkington, Colleen

    2013-01-01

    This paper considers the question: What constitutes an optimal learning environment for Maori learners in foundation programmes? Using Kaupapa Maori methodology, nearly 100 adult Maori (Indigenous) students in Aotearoa/New Zealand were interviewed from a range of tertiary providers of foundation programmes. State-funded foundation programmes that…

  1. 49 CFR 230.77 - Foundation brake gear.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Foundation brake gear. 230.77 Section 230.77... Tenders Brake and Signal Equipment § 230.77 Foundation brake gear. (a) Maintenance. Foundation brake gear shall be maintained in a safe and suitable condition for service. Levers, rods, brake beams,...

  2. 49 CFR 230.77 - Foundation brake gear.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Foundation brake gear. 230.77 Section 230.77... Tenders Brake and Signal Equipment § 230.77 Foundation brake gear. (a) Maintenance. Foundation brake gear shall be maintained in a safe and suitable condition for service. Levers, rods, brake beams,...

  3. 49 CFR 230.77 - Foundation brake gear.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Foundation brake gear. 230.77 Section 230.77... Tenders Brake and Signal Equipment § 230.77 Foundation brake gear. (a) Maintenance. Foundation brake gear shall be maintained in a safe and suitable condition for service. Levers, rods, brake beams,...

  4. 49 CFR 230.77 - Foundation brake gear.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Foundation brake gear. 230.77 Section 230.77... Tenders Brake and Signal Equipment § 230.77 Foundation brake gear. (a) Maintenance. Foundation brake gear shall be maintained in a safe and suitable condition for service. Levers, rods, brake beams,...

  5. 49 CFR 230.77 - Foundation brake gear.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Foundation brake gear. 230.77 Section 230.77... Tenders Brake and Signal Equipment § 230.77 Foundation brake gear. (a) Maintenance. Foundation brake gear shall be maintained in a safe and suitable condition for service. Levers, rods, brake beams,...

  6. Measure Guideline. Hybrid Foundation Insulation Retrofits

    SciTech Connect

    Ueno, K.; Lstiburek, J.

    2012-05-01

    This measure guideline provides recommendations for designs and variations for retrofit hybrid assemblies in improving interior foundation insulation and water management of basements. Variations include closed cell spray foam (ccSPF) with membrane waterproofing or air gap membrane drainage layers, rigid board foam insulation at flat walls (cast concrete or CMU block), a “partial drainage” detail making use of the bulk water drainage that occurs through the field of a rubble stone wall, and non-drained spray foam assemblies (including slab insulation).

  7. Measure Guideline: Hybrid Foundation Insulation Retrofits

    SciTech Connect

    Ueno, K.; Lstiburek, J.

    2012-05-01

    This measure guideline provides recommendations for designs and variations for retrofit hybrid assemblies in improving interior foundation insulation and water management of basements. Variations include closed cell spray foam (ccSPF) with membrane waterproofing or air gap membrane drainage layers, rigid board foam insulation at flat walls (cast concrete or CMU block), a 'partial drainage' detail making use of the bulk water drainage that occurs through the field of a rubble stone wall, and non-drained spray foam assemblies (including slab insulation).

  8. Analysis of stone-column reinforced foundations

    NASA Astrophysics Data System (ADS)

    Lee, J. S.; Pande, G. N.

    1998-12-01

    A numerical model is proposed to analyse elastic as well as elastoplastic behaviour of stone-column reinforced foundations. The stone-columns are assumed to be dispersed within the in situ soil and a homogenization technique is invoked to establish equivalent material properties for in situ soil and stone-column composite. The difficulties encountered in carrying out elastoplastic analyses of composite materials are overcome by adopting a separate yield function for each of the constituent materials and a sub-iteration procedure within an implicit backward Euler stress integration scheme. In the proposed procedure, equilibrium as well as kinematic conditions implied in the homogenization procedure are satisfied for both elastic as well as elastoplastic stress states.The proposed model is implemented in an axi-symmetric finite element code and numerical prediction is made for the behaviour of model circular footings resting on stone-column reinforced foundations. This prediction indicates good agreement with experimental observation. Finally, a new scheme in which the length of stone-column is variable is proposed and its behaviour is examined through a numerical example.

  9. Antennal cropping during colony foundation in termites

    PubMed Central

    Nalepa, Christine A.; Evans, Theodore A.; Lenz, Michael

    2011-01-01

    Abstract The literature on pairing and mating behavior in termites indicates that a number of distal antennal segments in dealates of both sexes are often removed during colony foundation, with terms such as amputation, mutilation and cannibalism typically employed to report the phenomenon. Here we propose the use of the phrase ‘antennal cropping’ to describe the behavior, and assess naturally occurring levels of its occurrence by comparing the number of antennal segments in museum specimens of alates and dealates in 16 species of Australian termites (four families), supplemented by analyzing published data on Coptotermes gestroi. Dealates had significantly fewer antennal segments than alates in 14 of the 16 termite species, with both exceptions belonging to the family Termitidae. Levels of antennal cropping were not significantly different between the sexes but did vary by family. Dealates in the Kalotermitidae removed the most segments (41.3%) and those in the Termitidae removed the fewest (8.9%). We discuss the biological significance of this phylogenetically widespread termite behavior, and suggest that controlled antennal cropping is not only a normal part of their behavioral repertoire but also a key influence that changes the conduct and physiology of the royal pair during the initial stages of colony foundation. PMID:22287897

  10. California settles lawsuit by AIDS Healthcare Foundation.

    PubMed

    1999-04-01

    The California Department of Health Services agreed to settle a lawsuit alleging it withheld funding from the AIDS Healthcare Foundation (AHF) in retaliation for AHF's advocacy on behalf of its clients. The public protest arose when the department attempted to cite one of the AHF hospices for not having a licensed nursing home administrator, which would have blocked Medi-Cal payments for patient care. For the type of facility being cited, having a nursing home administrator is not a requirement under State regulations. AHF charged the state with engaging in a pattern of discrimination, in violation of the Americans with Disabilities Act, the Federal Rehabilitation Act, and California's Unruh Civil Rights Act. A U.S. District judge granted summary judgment to the state on all claims except one transferring AHF's oversight responsibility to a county without AHF facilities. The transfer was viewed as having been aimed at AHF lobbying efforts and as an attempt to silence the foundation. The settlement returned AHF monitoring to Los Angeles County and dropped its claim that the two hospices had to hire a licensed nursing home administrator.

  11. Foundations for Measuring Volume Rendering Quality

    NASA Technical Reports Server (NTRS)

    Williams, Peter L.; Uselton, Samuel P.; Chancellor, Marisa K. (Technical Monitor)

    1997-01-01

    The goal of this paper is to provide a foundation for objectively comparing volume rendered images. The key elements of the foundation are: (1) a rigorous specification of all the parameters that need to be specified to define the conditions under which a volume rendered image is generated; (2) a methodology for difference classification, including a suite of functions or metrics to quantify and classify the difference between two volume rendered images that will support an analysis of the relative importance of particular differences. The results of this method can be used to study the changes caused by modifying particular parameter values, to compare and quantify changes between images of similar data sets rendered in the same way, and even to detect errors in the design, implementation or modification of a volume rendering system. If one has a benchmark image, for example one created by a high accuracy volume rendering system, the method can be used to evaluate the accuracy of a given image.

  12. Teachers and the foundations of intercultural interaction

    NASA Astrophysics Data System (ADS)

    Günay, Oya

    2016-08-01

    With the effects of globalisation, the number of people exposed to intercultural interaction has increased significantly. One of the most affected sectors is education. In parallel to the increase in numbers of students going abroad for tertiary education, primary and secondary education classes have also become culturally and religiously more diverse, mainly due to the effects of migration. With the increase in cultural diversity among their students, teachers find themselves facing new challenges. In order to be able to effectively encourage cultural exchange and intercultural dialogue, teachers need to cultivate their own intercultural competence. However, instead of directly jumping to the end result, this paper focuses on the very foundations of any intercultural interaction, namely self-awareness - of one's own normative settings -, acceptance of the equality of different cultural approaches, and strategies for how these can be transformed into personal attributes. The author highlights the importance of the internalisation of a belief in order to be able to reflect it in one's behaviour and convey to others the sense that they are genuinely accepted as they are. Self-Determination Theory (SDT) provides important insights into how and under which conditions internalisation can take place. Combining the insights gained from SDT with questioning techniques used by coaching experts, the author drafts a set of self-assessment questions which aim to help teachers reflect on the foundations of their intercultural interactions, gauge their level of internalisation and define the areas they have to focus on in order to cultivate their intercultural competence.

  13. The 20th Annual Prostate Cancer Foundation Scientific Retreat report.

    PubMed

    Miyahira, Andrea K; Simons, Jonathan W; Soule, Howard R

    2014-06-01

    The 20th Annual Prostate Cancer Foundation (PCF) Scientific Retreat was held from October 24 to 26, 2013, in National Harbor, Maryland. This event is held annually for the purpose of convening a diverse group of leading experimental and clinical researchers from academia, industry, and government to present and discuss critical and emerging topics relevant to prostate cancer (PCa) biology, and the diagnosis, prognosis, and treatment of PCa patients, with a focus on results that will lend to treatments for the most life-threatening stages of this disease. The themes that were highlighted at this year's event included: (i) mechanisms of PCa initiation and progression: cellular origins, neurons and neuroendocrine PCa, long non-coding RNAs, epigenetics, tumor cell metabolism, tumor-immune interactions, and novel molecular mechanisms; (ii) advancements in precision medicine strategies and predictive biomarkers of progression, survival, and drug sensitivities, including the analysis of circulating tumor cells and cell-free tumor DNA-new methods for liquid biopsies; (iii) new treatments including epigenomic therapy and immunotherapy, discovery of new treatment targets, and defining and targeting mechanisms of resistance to androgen-axis therapeutics; and (iv) new experimental and clinical epidemiology methods and techniques, including PCa population studies using patho-epidemiology.

  14. Moral foundations vignettes: a standardized stimulus database of scenarios based on moral foundations theory.

    PubMed

    Clifford, Scott; Iyengar, Vijeth; Cabeza, Roberto; Sinnott-Armstrong, Walter

    2015-12-01

    Research on the emotional, cognitive, and social determinants of moral judgment has surged in recent years. The development of moral foundations theory (MFT) has played an important role, demonstrating the breadth of morality. Moral psychology has responded by investigating how different domains of moral judgment are shaped by a variety of psychological factors. Yet, the discipline lacks a validated set of moral violations that span the moral domain, creating a barrier to investigating influences on judgment and how their neural bases might vary across the moral domain. In this paper, we aim to fill this gap by developing and validating a large set of moral foundations vignettes (MFVs). Each vignette depicts a behavior violating a particular moral foundation and not others. The vignettes are controlled on many dimensions including syntactic structure and complexity making them suitable for neuroimaging research. We demonstrate the validity of our vignettes by examining respondents' classifications of moral violations, conducting exploratory and confirmatory factor analysis, and demonstrating the correspondence between the extracted factors and existing measures of the moral foundations. We expect that the MFVs will be beneficial for a wide variety of behavioral and neuroimaging investigations of moral cognition. PMID:25582811

  15. Moral foundations vignettes: a standardized stimulus database of scenarios based on moral foundations theory

    PubMed Central

    Iyengar, Vijeth; Cabeza, Roberto; Sinnott-Armstrong, Walter

    2016-01-01

    Research on the emotional, cognitive, and social determinants of moral judgment has surged in recent years. The development of moral foundations theory (MFT) has played an important role, demonstrating the breadth of morality. Moral psychology has responded by investigating how different domains of moral judgment are shaped by a variety of psychological factors. Yet, the discipline lacks a validated set of moral violations that span the moral domain, creating a barrier to investigating influences on judgment and how their neural bases might vary across the moral domain. In this paper, we aim to fill this gap by developing and validating a large set of moral foundations vignettes (MFVs). Each vignette depicts a behavior violating a particular moral foundation and not others. The vignettes are controlled on many dimensions including syntactic structure and complexity making them suitable for neuroimaging research. We demonstrate the validity of our vignettes by examining respondents’ classifications of moral violations, conducting exploratory and confirmatory factor analysis, and demonstrating the correspondence between the extracted factors and existing measures of the moral foundations. We expect that the MFVs will be beneficial for a wide variety of behavioral and neuroimaging investigations of moral cognition. PMID:25582811

  16. Moral foundations vignettes: a standardized stimulus database of scenarios based on moral foundations theory.

    PubMed

    Clifford, Scott; Iyengar, Vijeth; Cabeza, Roberto; Sinnott-Armstrong, Walter

    2015-12-01

    Research on the emotional, cognitive, and social determinants of moral judgment has surged in recent years. The development of moral foundations theory (MFT) has played an important role, demonstrating the breadth of morality. Moral psychology has responded by investigating how different domains of moral judgment are shaped by a variety of psychological factors. Yet, the discipline lacks a validated set of moral violations that span the moral domain, creating a barrier to investigating influences on judgment and how their neural bases might vary across the moral domain. In this paper, we aim to fill this gap by developing and validating a large set of moral foundations vignettes (MFVs). Each vignette depicts a behavior violating a particular moral foundation and not others. The vignettes are controlled on many dimensions including syntactic structure and complexity making them suitable for neuroimaging research. We demonstrate the validity of our vignettes by examining respondents' classifications of moral violations, conducting exploratory and confirmatory factor analysis, and demonstrating the correspondence between the extracted factors and existing measures of the moral foundations. We expect that the MFVs will be beneficial for a wide variety of behavioral and neuroimaging investigations of moral cognition.

  17. Another Foundation Goes to School: The Panasonic Foundation's School Restructuring Program.

    ERIC Educational Resources Information Center

    Sa, Sophie

    1992-01-01

    The Panasonic Foundation made the improvement of elementary and secondary education its primary mission. The article describes its partnership program which involved it in long-term, intensive relationships with urban school districts. Evaluation of the partnership indicates it has been central in promoting reflective thinking and educational…

  18. Foundational issues concerning taxa and taxon names.

    PubMed

    Ereshefsky, Marc

    2007-04-01

    In a series of articles, Rieppel (2005, Biol. Philos. 20:465-487; 2006a, Cladistics 22:186-197; 2006b, Systematist 26:5-9), Keller et al. (2003, Bot. Rev. 69:93-110), and Nixon and Carpenter (2000, Cladistics 16:298-318) criticize the philosophical foundations of the PhyloCode. They argue that species and higher taxa are not individuals, and they reject the view that taxon names are rigid designators. Furthermore, they charge supporters of the individuality thesis and rigid designator theory with assuming essentialism, committing logical inconsistencies, and offering proposals that render taxonomy untestable. These charges are unsound. Such charges turn on confusions over rigid designator theory and the distinction between kinds and individuals. In addition, Rieppel's, Keller et al.'s, and Nixon and Carpenter's proposed alternatives are no better and have their own problems. The individuality thesis and rigid designator theory should not be quickly abandoned. PMID:17464884

  19. Statistical foundations of liquid-crystal theory

    PubMed Central

    Seguin, Brian; Fried, Eliot

    2013-01-01

    We develop a mechanical theory for systems of rod-like particles. Central to our approach is the assumption that the external power expenditure for any subsystem of rods is independent of the underlying frame of reference. This assumption is used to derive the basic balance laws for forces and torques. By considering inertial forces on par with other forces, these laws hold relative to any frame of reference, inertial or noninertial. Finally, we introduce a simple set of constitutive relations to govern the interactions between rods and find restrictions necessary and sufficient for these laws to be consistent with thermodynamics. Our framework provides a foundation for a statistical mechanical derivation of the macroscopic balance laws governing liquid crystals. PMID:23772091

  20. Safety as a Foundation for Project Success

    SciTech Connect

    Schepens, R.J.; Wiegman, S.A.; Shrader, T.; Coleman, S.J.

    2006-07-01

    This paper describes the importance of safety as a foundation for success on the largest and most complex cleanup project in the DOE complex. It describes the breadth of safety considerations ranging from design of systems to prevent low probability large consequence events to the day-to-day work hazard analysis and accident prevention. We are developing many first of a kind systems for handling, treating and disposing of the nation's largest volume of stored radioactive and hazardous waste. It is stored in aging underground tanks distributed across nearly 100 square miles. The project includes the development of retrieval and transfer systems, treatment and product handling, storage and disposal. When considering safety for a project of this magnitude it is necessary to include knowledge from almost every discipline as the breadth of hazard is large. Line ownership, worker involvement, and open communication are keys to safety success. (authors)

  1. Expert Meeting Report: Foundations Research Results

    SciTech Connect

    Ojczyk, C.; Huelman, P.; Carmody, J.

    2013-05-01

    In the Expert Meeting Plan, the NorthernSTAR Team proposed to host two Expert Meetings in calendar year 2011. Invitees to the meetings would include experts in the current field of study, other BA team members, and representatives from DOE and NREL. They will invite leading industry experts to present at these meetings. The Expert Meetings will focus on key systems areas that will be required to meet the Building America performance goals and shall be sufficiently narrow in scope that specific conclusions, action items, and delegation of future tasks can be identified and completed. The two expert meeting topics are 'Foundations' and 'Window Retrofit.' The first session is designed as a webinar only and the second will be a live meeting.

  2. New Directions For Foundations In Health Equity.

    PubMed

    Doykos, Patricia; Gray-Akpa, Kristina; Mitchell, Faith

    2016-08-01

    Rising income inequality and pessimism about the current and future status of race relations in the United States make this both a challenging time for the pursuit of health equity and also an important opportunity for action. We glean lessons from past and ongoing philanthropic investments in health equity and recommend approaches that can guide future work by foundations. Improving health equity is a complex process that must take into account a variety of factors that affect health, of which access to high-quality health care is just one element. Accordingly, improving health equity will require the combined forces of philanthropy, the public sector, and sectors that have not traditionally been identified with health. PMID:27503980

  3. Physical Foundations of Self-organizing Systems

    NASA Astrophysics Data System (ADS)

    Chatterjee, Atanu; Georgiev, Georgi

    2014-03-01

    The appearance of coherent global pattern due to local interactions is known as self-organization. Self-organization is a spontaneous process in highly non-equilibrium dissipative systems that form structures which tend to maximize energy dissipation by leveling off energy gradients. This follows as a direct consequence of the Second Law of Thermodynamics. Also, a local interaction embodies in the above definition a mechanistic dimension to self-organization. The link between mechanics and the Second Law of Thermodynamics lie in the Principle of Least Action, a strong law of nature that is obeyed in every spontaneous process. Thus, self-organization rests on two basic foundational principles of nature namely, the Second Law of Thermodynamics and the Principle of Least Action. We attempt to develop a formal definition of self-organization based on those principles.

  4. Foundations for a natural science of philosophy

    PubMed Central

    Fraley, Lawrence E.

    1999-01-01

    The functional relations among philosophy, science, technology, and intuition are examined. Those domains are each defined as behaviors, and each of them is then classified either as verbal, nonverbal, or both. Finally, those classes of behavior are organized into one integral behavioral system. The concept of a science of philosophy is introduced. A science and technology of philosophy are not only possible but necessary. Such an approach to the discipline of philosophy could lead to a new disciplinary structure for philosophy. Philosophy could be taught in academic departments as a verbal behavioral science. The discipline of behaviorology provides the foundations necessary to capacitate the traditional discipline of philosophy as a science and technology of verbal behavior commensurate with its potential cultural mission. PMID:22477161

  5. Information architecture. Volume 1, The foundations

    SciTech Connect

    1995-03-01

    The Information Management Planning and Architecture Coordinating Team was formed to establish an information architecture framework to meet DOE`s current and future information needs. This department- wide activity was initiated in accordance with the DOE Information Management Strategic Plan; it also supports the Departmental Strategic Plan. It recognizes recent changes in emphasis as reflected in OMB Circular A-130 and the Information Resources Management Planning Process Improvement Team recommendations. Sections of this document provides the foundation for establishing DOE`s Information Architecture: Background, Business Case (reduced duplication of effort, increased integration of activities, improved operational capabilities), Baseline (technology baseline currently in place within DOE), Vision (guiding principles for future DOE Information Architecture), Standards Process, Policy and Process Integration (describes relations between information architecture and business processes), and Next Steps. Following each section is a scenario. A glossary of terms is provided.

  6. Patient Engagement: Time to Shake the Foundations.

    PubMed

    Thompson, Leslee

    2015-01-01

    Something big is happening in healthcare. It's not the new Apple Watch, 3D printing or the advent of personalized medicine. It's people power. And, it is starting to shake up the very foundation on which healthcare systems around the world have been built. Healthcare professionals and hospitals are iconic features on a healthcare landscape that has been purpose-built with castles, moats and defence artillery. Turf protection, often under the guise of "patient protection," has become so ingrained in the way things are that few recognize what it has become. Fooks et al. step gently into this somewhat dangerous territory for "insiders" of the system to tread; yet in my view, they do not go far enough. PMID:26888321

  7. Patient Engagement: Time to Shake the Foundations.

    PubMed

    Thompson, Leslee

    2015-01-01

    Something big is happening in healthcare. It's not the new Apple Watch, 3D printing or the advent of personalized medicine. It's people power. And, it is starting to shake up the very foundation on which healthcare systems around the world have been built. Healthcare professionals and hospitals are iconic features on a healthcare landscape that has been purpose-built with castles, moats and defence artillery. Turf protection, often under the guise of "patient protection," has become so ingrained in the way things are that few recognize what it has become. Fooks et al. step gently into this somewhat dangerous territory for "insiders" of the system to tread; yet in my view, they do not go far enough.

  8. Foundation on Economic Trends v. Bowen.

    PubMed

    1989-10-01

    The National Enviromental Policy Act requires that government agencies make a detailed enviromental impact statement (EIS) for all research significantly affecting the environment. These statements must be supplemented if the project substantially changes or if new information is obtained. The Foundation on Economic Trends argued that three developments in recombinant DNA research will significantly alter the enviromental impact, thereby mandating a new EIS by the National Institutes of Health (NIH). These developments are cloning oncogenic viruses, engineering the human immunodeficiency virus into cells not normally susceptible to it, and introducing AIDS genetic codes into mice. The U.S. District Court, District of Columbia, held that the first two projects do not pose a greater risk and that the enviromental assessment being prepared by NIH on the third satisfies the requirements of the National Enviromental Policy Act. PMID:11648296

  9. Foundations of Intervention Research in Instrumental Practice

    PubMed Central

    Hatfield, Johannes L.; Lemyre, Pierre-Nicolas

    2016-01-01

    The goals of the present study are to evaluate, implement, and adapt psychological skills used in the realm of sports into music performance. This research project also aims to build foundations on how to implement future interventions to guide music students on how to optimize practice toward performance. A 2-month psychological skills intervention was provided to two students from the national music academy's bachelor program in music performance to better understand how to adapt and construct psychological skills training programs for performing music students. The program evaluated multiple intervention tools including the use of questionnaires, performance profiling, iPads, electronic practice logs, recording the perceived value of individual and combined work, as well as the effectiveness of different communication forms. Perceived effects of the intervention were collected through semi-structured interviews, observations, and logs. PMID:26834660

  10. Foundational Forces & Hidden Variables in Technology Commercialization

    NASA Astrophysics Data System (ADS)

    Barnett, Brandon

    2011-03-01

    The science of physics seems vastly different from the process of technology commercialization. Physics strives to understand our world through the experimental deduction of immutable laws and dependent variables and the resulting macro-scale phenomenon. In comparison, the~goal of business is to make a profit by addressing the needs, preferences, and whims of individuals in a market. It may seem that this environment is too dynamic to identify all the hidden variables and deduct the foundational forces that impact a business's ability to commercialize innovative technologies. One example of a business ``force'' is found in the semiconductor industry. In 1965, Intel co-founder Gordon Moore predicted that the number of transistors incorporated in a chip will approximately double every 24 months. Known as Moore's Law, this prediction has become the guiding principle for the semiconductor industry for the last 40 years. Of course, Moore's Law is not really a law of nature; rather it is the result of efforts by Intel and the entire semiconductor industry. A closer examination suggests that there are foundational principles of business that underlie the macro-scale phenomenon of Moore's Law. Principles of profitability, incentive, and strategic alignment have resulted in a coordinated influx of resources that has driven technologies to market, increasing the profitability of the semiconductor industry and optimizing the fitness of its participants. New innovations in technology are subject to these same principles. So, in addition to traditional market forces, these often unrecognized forces and variables create challenges for new technology commercialization. In this talk, I will draw from ethnographic research, complex adaptive theory, and industry data to suggest a framework with which to think about new technology commercialization. Intel's bio-silicon initiative provides a case study.

  11. Colony Foundation in an Oceanic Seabird

    PubMed Central

    Munilla, Ignacio; Genovart, Meritxell; Paiva, Vitor H.; Velando, Alberto

    2016-01-01

    Seabirds are colonial vertebrates that despite their great potential for long-range dispersal and colonization are reluctant to establish in novel locations, often recruiting close to their natal colony. The foundation of colonies is therefore a rare event in most seabird species and little is known about the colonization process in this group. The Cory’s shearwater (Calonectris diomedea) is a pelagic seabird that has recently established three new colonies in Galicia (NE Atlantic) thus expanding its distribution range 500 km northwards. This study aimed to describe the establishment and early progress of the new Galician populations and to determine the genetic and morphometric characteristics of the individuals participating in these foundation events. Using 10 microsatellite loci, we tested the predictions supported by different seabird colonization models. Possibly three groups of non-breeders, adding up to around 200 birds, started visiting the Galician colonies in the mid 2000’s and some of them eventually laid eggs and reproduced, thus establishing new breeding colonies. The Galician populations showed a high genetic diversity and a frequency of private alleles similar to or even higher than some of the large historical populations. Most individuals were assigned to several Atlantic populations and a few (if any) to Mediterranean colonies. Our study suggests that a large and admixed population is settling in Galicia, in agreement with predictions from island metapopulation models of colonization. Multiple source colonies imply that some birds colonizing Galicia were dispersing from very distant colonies (> 1500 km). Long-distance colonizations undertaken by relatively large and admixed groups of colonizers can help to explain the low levels of genetic structure over vast areas that are characteristic of most oceanic seabird species. PMID:26909694

  12. Colony Foundation in an Oceanic Seabird.

    PubMed

    Munilla, Ignacio; Genovart, Meritxell; Paiva, Vitor H; Velando, Alberto

    2016-01-01

    Seabirds are colonial vertebrates that despite their great potential for long-range dispersal and colonization are reluctant to establish in novel locations, often recruiting close to their natal colony. The foundation of colonies is therefore a rare event in most seabird species and little is known about the colonization process in this group. The Cory's shearwater (Calonectris diomedea) is a pelagic seabird that has recently established three new colonies in Galicia (NE Atlantic) thus expanding its distribution range 500 km northwards. This study aimed to describe the establishment and early progress of the new Galician populations and to determine the genetic and morphometric characteristics of the individuals participating in these foundation events. Using 10 microsatellite loci, we tested the predictions supported by different seabird colonization models. Possibly three groups of non-breeders, adding up to around 200 birds, started visiting the Galician colonies in the mid 2000's and some of them eventually laid eggs and reproduced, thus establishing new breeding colonies. The Galician populations showed a high genetic diversity and a frequency of private alleles similar to or even higher than some of the large historical populations. Most individuals were assigned to several Atlantic populations and a few (if any) to Mediterranean colonies. Our study suggests that a large and admixed population is settling in Galicia, in agreement with predictions from island metapopulation models of colonization. Multiple source colonies imply that some birds colonizing Galicia were dispersing from very distant colonies (> 1500 km). Long-distance colonizations undertaken by relatively large and admixed groups of colonizers can help to explain the low levels of genetic structure over vast areas that are characteristic of most oceanic seabird species. PMID:26909694

  13. Improving Access to Foundational Energy Performance Data

    SciTech Connect

    Studer, D.; Livingood, W.; Torcellini, P.

    2014-08-01

    Access to foundational energy performance data is key to improving the efficiency of the built environment. However, stakeholders often lack access to what they perceive as credible energy performance data. Therefore, even if a stakeholder determines that a product would increase efficiency, they often have difficulty convincing their management to move forward. Even when credible data do exist, such data are not always sufficient to support detailed energy performance analyses, or the development of robust business cases. One reason for this is that the data parameters that are provided are generally based on the respective industry norms. Thus, for mature industries with extensive testing standards, the data made available are often quite detailed. But for emerging technologies, or for industries with less well-developed testing standards, available data are generally insufficient to support robust analysis. However, even for mature technologies, there is no guarantee that the data being supplied are the same data needed to accurately evaluate a product?s energy performance. To address these challenges, the U.S. Department of Energy funded development of a free, publically accessible Web-based portal, the Technology Performance Exchange(TM), to facilitate the transparent identification, storage, and sharing of foundational energy performance data. The Technology Performance Exchange identifies the intrinsic, technology-specific parameters necessary for a user to perform a credible energy analysis and includes a robust database to store these data. End users can leverage stored data to evaluate the site-specific performance of various technologies, support financial analyses with greater confidence, and make better informed procurement decisions.

  14. ELECTRONIC SCHOLARLY PUBLISHING: FOUNDATIONS OF GENETICS

    SciTech Connect

    Robert J. Robbins

    2002-11-10

    As the Human Genome Project (HGP) moves toward its successful completion, more and more people have become interested in understanding this project and its results. Since the HGP has significant ethical, legal, and social implications for all citizens, the number of individuals who do, or should wish to become familiar with the project is high. In addition to its importance in the training of professional geneticists, the HGP is of special relevance for undergraduate training in basic biology, and even for high-school and other K-12 education. Understanding the results of HGP research requires a familiarity with the notions of basic genetics. Unlike other disciplines that evolved over centuries, modern genetics began abruptly with the rediscovery of Gregor Mendel's work in 1900. Within a few years, fundamental concepts were elaborated and the foundations of genetics established. Because genetics developed so rapidly in just a few decades after 1900, the literature of that period constitutes a valuable resource even now. It may be read profitably by students and scientists wishing to understand the foundations of their field, as well as by laymen or historians of science. Unfortunately, the early literature is rapidly becoming almost inaccessible. Newer libraries do not hold older journals and even established libraries are moving their materials from that era into hard-to-reach (and impossible to browse) long-term storage in remote warehouses. To be sure, key studies from the early work are discussed in nearly all textbooks, but a comparison of these presentations with the actual literature shows that most textbook treatments have essentially mythologized the early work so that real understanding is lost. There have been several collections of classic works developed over the years (although none lately), but these suffer from the effects of the necessary, but nonetheless pernicious, highly selective sampling that accompanies these projects. Such selectivity

  15. 76 FR 11822 - Comment Request: National Science Foundation-Applicant Survey

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-03

    ... From the Federal Register Online via the Government Publishing Office NATIONAL SCIENCE FOUNDATION Comment Request: National Science Foundation--Applicant Survey AGENCY: National Science Foundation. ACTION: Notice. SUMMARY: The National Science Foundation (NSF) is announcing plans to request renewed...

  16. Medical foundations: one model for hospital-physician alignment.

    PubMed

    Feldman, Joan W

    2012-05-01

    Some states that enforce a corporate practice of medicine prohibition have created medical foundation statutes allowing hospitals or health systems to own corporations providing physician services. Medical foundations may be useful in the coordination of care through employed or contracted physicians. Medical foundations that qualify as a tax-exempt entities have lower risks associated with tax-exempt rules as long as payments to physicians are reasonable and don't result in private inurement. PMID:22616507

  17. Medical foundations: one model for hospital-physician alignment.

    PubMed

    Feldman, Joan W

    2012-05-01

    Some states that enforce a corporate practice of medicine prohibition have created medical foundation statutes allowing hospitals or health systems to own corporations providing physician services. Medical foundations may be useful in the coordination of care through employed or contracted physicians. Medical foundations that qualify as a tax-exempt entities have lower risks associated with tax-exempt rules as long as payments to physicians are reasonable and don't result in private inurement.

  18. The expansion of the Foundation Programme in psychiatry†

    PubMed Central

    Perry, Jennifer; Boyle, Ann; Wessely, Simon

    2016-01-01

    The Broadening the Foundation Programme report has led to an expansion in the number of psychiatry foundation placements. This change will have far-reaching benefits for foundation doctors doing psychiatry, no matter what their future career intentions. Doctors will develop a better understanding of mental illness, they will improve their communication skills and they will gain experience of working within multidisciplinary teams. Recruitment into psychiatry is also likely to improve. The Royal College of Psychiatrists is putting in place a number of measures to ensure that placements are of a high quality so that foundation doctors have a good experience of psychiatry. PMID:27512595

  19. Foundations and Public Information: Sunshine or Shadow? Preliminary Findings from a Study of the Public Information Accountability of the Country's Largest Foundations.

    ERIC Educational Resources Information Center

    Bruce, Ellen; And Others

    The types of written information that the largest foundations in the United States voluntarily make available to the public were studied. Of the 208 foundations contacted, 150 were the largest grant-making foundations, 30 were the largest community foundations, and 28 were the largest corporate foundations. The response rate to written and…

  20. Twentieth anniversary of American Vascular Association/Lifeline Foundation: a celebration.

    PubMed

    Pearce, William H; Mannick, John A; Clowes, Alexander W; Yao, James S T

    2008-06-01

    The American Vascular Association/Lifeline Foundation is celebrating its 20th anniversary this year. This remarkable two-decade journey represents a cumulative effort by the leaders and members of the Society for Vascular Surgery (SVS). For the historical record, we would like to chart the sequence of events leading to various programs. In 1986, the Executive Council of SVS approved the formation of an Education/Research Foundation, from which the Lifeline Foundation evolved, with the mission to support the career development of young research-oriented vascular surgeons. Since that time, Lifeline has awarded 141 Student Fellowships, 21 Wylie Traveling Fellowships, 17 Mentored Clinical Scientist Development (K08) Awards, and three Mentored Patient-Oriented Research Career Development (K23) Awards. In 2001, the American Vascular Association (AVA) was established under the aegis of American Association for Vascular Surgery (formerly International Society for Cardiovascular Surgery-North American Chapter). In 2004, with the merger of the SVS and the American Association of Vascular Surgery into a single entity (SVS), Lifeline and the AVA merged into a single foundation, the AVA. As AVA/Lifeline is poised to launch a campaign for an endowment fund, we hope this report will let the members of the SVS know what has been accomplished, what we plan to do, and, most importantly, what we need to do in the future.

  1. Neuronal foundations of human numerical representations.

    PubMed

    Eger, E

    2016-01-01

    The human species has developed complex mathematical skills which likely emerge from a combination of multiple foundational abilities. One of them seems to be a preverbal capacity to extract and manipulate the numerosity of sets of objects which is shared with other species and in humans is thought to be integrated with symbolic knowledge to result in a more abstract representation of numerical concepts. For what concerns the functional neuroanatomy of this capacity, neuropsychology and functional imaging have localized key substrates of numerical processing in parietal and frontal cortex. However, traditional fMRI mapping relying on a simple subtraction approach to compare numerical and nonnumerical conditions is limited to tackle with sufficient precision and detail the issue of the underlying code for number, a question which more easily lends itself to investigation by methods with higher spatial resolution, such as neurophysiology. In recent years, progress has been made through the introduction of approaches sensitive to within-category discrimination in combination with fMRI (adaptation and multivariate pattern recognition), and the present review summarizes what these have revealed so far about the neural coding of individual numbers in the human brain, the format of these representations and parallels between human and monkey neurophysiology findings. PMID:27339006

  2. Ethical foundations of the radiological protection system.

    PubMed

    Cho, K W

    2016-06-01

    The International Commission on Radiological Protection (ICRP) has established Task Group 94 under Committee 4 to develop a report on the ethical foundations of the system of radiological protection. The aim of this report is to consolidate the basis of ICRP recommendations, to improve understanding of the system, and to provide a basis for communication on radiation risk and its perception. Through a series of workshops organised by the Commission in cooperation with the International Radiation Protection Association and its associate societies involving radiological protection professionals and specialists of ethics around the world, Task Group 94 has identified the key ethical and social values underpinning the system of radiological protection. The purpose of eliciting the ethical principles and values of the radiological protection system is not only to clarify the rationale for recommendations made by the Commission, but also to assist in discussions related to its practical implementation. A clear understanding of the ethical principles will help resolve dilemmas caused by potential conflicts in actions that might be considered, or decisions that must be made.

  3. Finite Volume Methods: Foundation and Analysis

    NASA Technical Reports Server (NTRS)

    Barth, Timothy; Ohlberger, Mario

    2003-01-01

    Finite volume methods are a class of discretization schemes that have proven highly successful in approximating the solution of a wide variety of conservation law systems. They are extensively used in fluid mechanics, porous media flow, meteorology, electromagnetics, models of biological processes, semi-conductor device simulation and many other engineering areas governed by conservative systems that can be written in integral control volume form. This article reviews elements of the foundation and analysis of modern finite volume methods. The primary advantages of these methods are numerical robustness through the obtention of discrete maximum (minimum) principles, applicability on very general unstructured meshes, and the intrinsic local conservation properties of the resulting schemes. Throughout this article, specific attention is given to scalar nonlinear hyperbolic conservation laws and the development of high order accurate schemes for discretizing them. A key tool in the design and analysis of finite volume schemes suitable for non-oscillatory discontinuity capturing is discrete maximum principle analysis. A number of building blocks used in the development of numerical schemes possessing local discrete maximum principles are reviewed in one and several space dimensions, e.g. monotone fluxes, E-fluxes, TVD discretization, non-oscillatory reconstruction, slope limiters, positive coefficient schemes, etc. When available, theoretical results concerning a priori and a posteriori error estimates are given. Further advanced topics are then considered such as high order time integration, discretization of diffusion terms and the extension to systems of nonlinear conservation laws.

  4. Justice foundations for the Comprehensive Law Movement.

    PubMed

    Dewhurst, Dale

    2010-01-01

    Authors examining the developing dispute resolution alternatives to the adversarial system have identified nine converging "vectors" or alternatives in what has been termed the Comprehensive Law Movement. These authors have sought to understand how the developing vectors can remain separate and vibrant movements while sharing common ground. Some analyze these developments as being within law and legal practice, others see them as alternative approaches to law, and still others take a combined approach. It will be impossible to understand how these vectors have meaningful differences from law and legal practice if the search is limited to looking within law and legal practice. It will be impossible to understand how these vectors have meaningful commonalities with law and legal practice if the search is limited to looking external to law and legal practice. Instead of comparing the vectors with the adversarial system, higher order criteria are required. What is needed is a comprehensive and internally consistent super-system of norms; one that can be used to evaluate the adversarial system and the evolving vectors on an equal footing. An Aristotelian natural law virtue theory of justice can: (a) provide a functional guiding definition of justice; (b) serve as a comprehensive and internally consistent super-system of norms; and (c) provide the theoretical and evaluative foundation required to clarify the relationships among the adversarial system and the developing vectors. Finally, it will become clear why the Comprehensive Law Movement might be more appropriately conceptualized as the Comprehensive Justice Movement. PMID:20880589

  5. The scientific foundation of anti-psychiatry.

    PubMed

    van Praag, H M

    1978-08-01

    Anti-psychiatry has exerted a substantial influence on the thoughts of workers in the field of mental hygiene; on those of the psychiatrically trained, but even much more on those without psychiatric training. Consequently it seemed important to me to investigate the strength of the foundation of this school of thought. This has been the objective of this study. The point of crystallization of anti-psychiatry is the labelling theory on the origin of deviant behaviour. The scientific status of anti-psychiatry stands or falls with that of the labelling theory. Since this theory has not been formulated in verifiable hypotheses, I ventured to formulate "theses", and then tested these against empirical obtained data. The results of this study were largely negative. The empirical material does not support the labelling theory, and in many cases even contradicts it. Consequently anti-psychiatry--as a model to explain the development of psychological disorders--has not a leg to stand on. The labelling theory has had great merits as a "sensitizing theory". It has given momentum to innovative tendencies in psychiatry. Now that it has proved to be untenable on its principal points, however, it should be abandoned. It has become a rubber check, which has no scientific buying-power. PMID:696382

  6. Foundations of the Bandera Abstraction Tools

    NASA Technical Reports Server (NTRS)

    Hatcliff, John; Dwyer, Matthew B.; Pasareanu, Corina S.; Robby

    2003-01-01

    Current research is demonstrating that model-checking and other forms of automated finite-state verification can be effective for checking properties of software systems. Due to the exponential costs associated with model-checking, multiple forms of abstraction are often necessary to obtain system models that are tractable for automated checking. The Bandera Tool Set provides multiple forms of automated support for compiling concurrent Java software systems to models that can be supplied to several different model-checking tools. In this paper, we describe the foundations of Bandera's data abstraction mechanism which is used to reduce the cardinality (and the program's state-space) of data domains in software to be model-checked. From a technical standpoint, the form of data abstraction used in Bandera is simple, and it is based on classical presentations of abstract interpretation. We describe the mechanisms that Bandera provides for declaring abstractions, for attaching abstractions to programs, and for generating abstracted programs and properties. The contributions of this work are the design and implementation of various forms of tool support required for effective application of data abstraction to software components written in a programming language like Java which has a rich set of linguistic features.

  7. Formal Foundations for Hierarchical Safety Cases

    NASA Technical Reports Server (NTRS)

    Denney, Ewen; Pai, Ganesh; Whiteside, Iain

    2015-01-01

    Safety cases are increasingly being required in many safety-critical domains to assure, using structured argumentation and evidence, that a system is acceptably safe. However, comprehensive system-wide safety arguments present appreciable challenges to develop, understand, evaluate, and manage, partly due to the volume of information that they aggregate, such as the results of hazard analysis, requirements analysis, testing, formal verification, and other engineering activities. Previously, we have proposed hierarchical safety cases, hicases, to aid the comprehension of safety case argument structures. In this paper, we build on a formal notion of safety case to formalise the use of hierarchy as a structuring technique, and show that hicases satisfy several desirable properties. Our aim is to provide a formal, theoretical foundation for safety cases. In particular, we believe that tools for high assurance systems should be granted similar assurance to the systems to which they are applied. To this end, we formally specify and prove the correctness of key operations for constructing and managing hicases, which gives the specification for implementing hicases in AdvoCATE, our toolset for safety case automation. We motivate and explain the theory with the help of a simple running example, extracted from a real safety case and developed using AdvoCATE.

  8. Ethical foundations of the radiological protection system.

    PubMed

    Cho, K W

    2016-06-01

    The International Commission on Radiological Protection (ICRP) has established Task Group 94 under Committee 4 to develop a report on the ethical foundations of the system of radiological protection. The aim of this report is to consolidate the basis of ICRP recommendations, to improve understanding of the system, and to provide a basis for communication on radiation risk and its perception. Through a series of workshops organised by the Commission in cooperation with the International Radiation Protection Association and its associate societies involving radiological protection professionals and specialists of ethics around the world, Task Group 94 has identified the key ethical and social values underpinning the system of radiological protection. The purpose of eliciting the ethical principles and values of the radiological protection system is not only to clarify the rationale for recommendations made by the Commission, but also to assist in discussions related to its practical implementation. A clear understanding of the ethical principles will help resolve dilemmas caused by potential conflicts in actions that might be considered, or decisions that must be made. PMID:26980798

  9. Strengthening the foundations of proliferation assessment tools.

    SciTech Connect

    Rexroth, Paul E.; Saltiel, David H.; Rochau, Gary Eugene; Cleary, Virginia D.; Ng, Selena; Greneche, Dominique; Giannangeli, Don; Charlton, William S.; Ford, David

    2007-09-01

    Robust and reliable quantitative proliferation assessment tools have the potential to contribute significantly to a strengthened nonproliferation regime and to the future deployment of nuclear fuel cycle technologies. Efforts to quantify proliferation resistance have thus far met with limited success due to the inherent subjectivity of the problem and interdependencies between attributes that lead to proliferation resistance. We suggest that these limitations flow substantially from weaknesses in the foundations of existing methodologies--the initial data inputs. In most existing methodologies, little consideration has been given to the utilization of varying types of inputs--particularly the mixing of subjective and objective data--or to identifying, understanding, and untangling relationships and dependencies between inputs. To address these concerns, a model set of inputs is suggested that could potentially be employed in multiple approaches. We present an input classification scheme and the initial results of testing for relationships between these inputs. We will discuss how classifying and testing the relationship between these inputs can help strengthen tools to assess the proliferation risk of nuclear fuel cycle processes, systems, and facilities.

  10. The philosophical foundations of Aleksandr R. Luria's neuropsychology.

    PubMed

    Eilam, Gavriela

    2003-12-01

    This article attempts to show that the cultural-historical psychological theory of Aleksandr R. Luria (Luriya) and his colleagues is based on the foundations of historical materialism. It argues in particular that Luria's psychology, neuropsychology, and brain theory are integrated in the same scientific research program and are based on the same philosophical premises, and that his theories must be interpreted in the Marxist context in which they are embedded. Luria's research program asserts that the development of higher mental functions depends on the appropriation of cultural means, particularly language, within social practice. Moreover, the brain structures underlying mental functions are also dependent on the appropriation of cultural means. Luria's clinical diagnosis and his program for rehabilitation of patients with brain lesions are based on his psychological theory and brain theory. The following analysis of Luria's comprehensive program will show that a socio-cultural non-reductive explanation of mental functions and their underlying brain structures may have implications for the philosophical discussion of the mind-brain problem. PMID:15025065

  11. National Kidney Foundation report on dialyzer reuse. Task Force on Reuse of Dialyzers, Council on Dialysis, National Kidney Foundation.

    PubMed

    1997-12-01

    The Council on Dialysis of the National Kidney Foundation convened an expert panel to evaluate the current practice and literature related to the reuse of hemodialyzers. The panel reviewed and evaluated literature related to reuse since the last report of the National Kidney Foundation recommendations on reuse was published in 1988. The group sought to develop a consensus concerning the effect of reuse of hemodialyzers on mortality; the efficiency of delivered hemodialysis when reused hemodialyzers are used in the clinical setting; the clinical effects of reused dialyzers as compared with dialyzers not reused on intradialytic symptoms; infections in patients using reused dialyzers; and the effect of reused dialyzers on complement activation, cytokine production, and beta2-microglobulin metabolism and clearance. In addition, the panel reviewed the literature on the potential toxicity of germicides used in the processing of dialyzers for reuse as well as recent changes in federally mandated regulations concerning labeling of dialyzers for reuse, the monitoring of the reuse process, and the effectiveness of reused dialyzers to achieve a prescribed delivered clearance as estimated by urea kinetic modeling or by percent urea reduction. The National Kidney Foundation takes no position for or against dialyzer reuse. The principal reason for the practice of reuse is economical. In view of the uncertainties related to the safety and biological impact of reuse procedures, the task force recommends that a full discussion of the issue of reuse and its potential beneficial and detrimental effects be undertaken with each patient. There is no conclusive evidence to substantiate the notion that either morbidity or mortality associated with single use or reuse is different. Microbial contamination of the water used for dialyzer reprocessing increases patient morbidity. The chemical quality of water used for dialyzer reprocessing should, at least, fall within the same standards as

  12. Anatomists Provide the Foundation for Learning Pathophysiology

    ERIC Educational Resources Information Center

    McBride, Jennifer M.; Bierer, S. B.

    2012-01-01

    The need for interdisciplinary graduate training programs which prepare students to conceptualize the application of their research in clinical settings continues to grow. Though several programs have been cultivated to address this need, demand still outweighs supply. The following describes a curriculum developed with the intent of incorporating…

  13. [THE FOUNDATIONS OF EVIDENCE-BASED MEDICINE].

    PubMed

    Pasleau, F

    2015-01-01

    The fundamentals of Evidence-Based Medicine (EBM) are the clinical experience, the application of best evidences from research and the consideration of patient expectations. It enabled significant progresses in the management of diseases with a low or multifactorial causality. But it has also led to unintended negative consequences, partly related to conflicts of interest. The objective of this article is to bring the attention back to the scientific rigor that must sustain the medical practice, namely in the occurrence : 1) formulating a question that addresses all the elements of an individual clinical situation; 2) exploring the literature systematically; 3) estimating the degree of confidence in the conclusions of clinical trials. EBM provides intuitive tools to address some uncomfortable concepts of biostatistics and to identify the biases and the embellished data that invalidate many studies. However, it is difficult to decide of the care of a single patient from observations issued from the comparison of'heterogeneous groups. Personalized medicine should help to overcome this difficulty and should facilitate clinical decision making by targeting the patients who are most likely to benefit from an intervention without much inconvenience. PMID:26285443

  14. Foundations for Young Children to the Indiana Academic Standards.

    ERIC Educational Resources Information Center

    Indiana State Dept. of Education, Indianapolis.

    Noting that young children need early childhood settings supporting the development of the full range of capacities that will serve as a foundation for future school learning, and that adults have an opportunity and an obligation to assist children in becoming active participants in the learning process, this document details foundations to…

  15. Sierra Health Foundation's Positive Youth Justice Initiative. Briefing Paper

    ERIC Educational Resources Information Center

    Sierra Health Foundation, 2012

    2012-01-01

    In December 2011, the Sierra Health Foundation board of directors approved a framework for a new youth development initiative. The framework built upon the foundation's recently concluded REACH Youth Development Program and incorporated findings and recommendations from the highly regarded "Healthy Youth/Healthy Regions" and "Renewing Juvenile…

  16. The National Science Foundation: Funding Opportunities for Social Workers

    ERIC Educational Resources Information Center

    Jaskyte, Kristina

    2005-01-01

    This article introduces the National Science Foundation as a potential funding source for social work researchers and describes the experience of one faculty member in seeking funding from this source. The author provides an overview of the foundation, discusses its programmatic structure, proposal preparation, selection criteria, and review…

  17. Foundation for Child Development Annual Report, 2001-2002.

    ERIC Educational Resources Information Center

    Foundation for Child Development, New York, NY.

    This annual report details the activities of the Foundation for Child Development (FCD) for 2001-2002. Beginning the report is a brief description of the Foundations mission, its funding priorities, and application procedures. The report then presents the joint statement of the chair, Karen Gerard, and the president, Ruby Takanishi, focusing on…

  18. Foundation for Child Development Annual Report, 1997/1998.

    ERIC Educational Resources Information Center

    Foundation for Child Development, New York, NY.

    This annual report details the activities of the Foundation for Child Development (FCD) for 1997-98. Included in the report is a discussion of the history and mission of the foundation and its funding priorities. The members of the Council, Board of Directors, Officers, and staff are listed. The report of the chair, Barbara Paul Robinson,…

  19. Foundation for Child Development (FCD) Annual Report, 1996/1997.

    ERIC Educational Resources Information Center

    Foundation for Child Development, New York, NY.

    This annual report details the 1996-97 activities of the Foundation for Child Development. Included in the report is a discussion of the history and mission of the foundation and its funding priorities. The members of the Council, Board of Directors, Officers, and staff are listed. The report of the chair, Barbara Paul Robinson, describes the…

  20. Foundation for Child Development Annual Report, 2000/2001.

    ERIC Educational Resources Information Center

    Foundation for Child Development, New York, NY.

    This annual report details the activities of the Foundation for Child Development (FCD) for 2000-2001. Beginning the report is a presentation of the Foundation's mission, its funding priorities, and application procedures. The report then lists the members of the Council, Board of Directors, Officers, and staff. This is followed by the joint…

  1. Foundation for Child Development Annual Report, 1998/1999.

    ERIC Educational Resources Information Center

    Foundation for Child Development, New York, NY.

    This annual report details the activities of the Foundation for Child Development (FCD) for 1998-99. Beginning the report is a discussion of the history and mission of the foundation, its funding priorities, and application procedures. The report lists the members of the Council, Board of Directors, Officers, and staff. The joint statement of the…

  2. Foundation Degree Students and Their Educational Decision-Making

    ERIC Educational Resources Information Center

    Greenbank, Paul

    2009-01-01

    Purpose: The purpose of this paper is to examine the decision-making process of students who decided to study for a foundation degree. Design/methodology/approach: The research involved interviewing 30 students who were on, or had recently completed, a business-related foundation degree. Findings: This study found that students were not adopting a…

  3. Report Carding: A Model for Foundation Portfolio Assessment

    ERIC Educational Resources Information Center

    Schmitz, Connie C.; Schillo, Barbara A.

    2005-01-01

    This article reviews changes in the accountability landscape that have occurred for foundations in recent years and several precedents for foundation performance assessment. The authors then present a model of portfolio assessment that is used for organizational accountability and learning. This model, which was piloted in 2002 and 2003 for the…

  4. The Irving Harris Foundation's Investment in the Professional Development Network

    ERIC Educational Resources Information Center

    Glink, Phyllis

    2012-01-01

    Phyllis Glink, the executive director of the Irving Harris Foundation, describes the Foundation's strategic approach to grantmaking in the infant and early childhood field. The Harris Professional Development Network evolved out of Irving Harris's growing appreciation for the importance of supporting very young children's mental health and…

  5. Foundations that Provide Support for Human Services: A Selected List.

    ERIC Educational Resources Information Center

    Smith, Bertha, Comp.

    Lists of foundations can aid the user in securing funding sources for projects in the areas of health, education, community development and/or social services. The user is cautioned that grantsmanship is a competitive process; grants application procedures vary from one foundation to another. In the absence of any specific guidelines, important…

  6. Faith in Welfare: The Origins of the Open Home Foundation

    ERIC Educational Resources Information Center

    Troughton, Geoffrey

    2013-01-01

    This article analyses the origins of the Open Home Foundation (OHF), a Christian social service provider that commenced in New Zealand in 1977. It interprets the Foundation's appeal, paying particular attention to the role of religious values and spirituality within the organisation. The article argues that OHF emerged and flourished from the…

  7. Foundation Degree Learning: An Educational Journey of Personal Development

    ERIC Educational Resources Information Center

    Herrera, Helena; Brown, David; Portlock, Jane

    2015-01-01

    The foundation degree is an intermediate-level qualification designed to widen participation in higher education while providing work-related skills and knowledge. It has a vocational focus and a pedagogic approach that integrates academic and work-based learning. Research into opportunities and the process of learning within foundation degrees is…

  8. The Empirical and Moral Foundations of the ISLLC Standards

    ERIC Educational Resources Information Center

    Murphy, Joseph

    2015-01-01

    Purpose: The purpose of this paper is to unpack the foundations for the national standards for school leaders in the USA. The author examines some of the background of the Standards from 1996 to 2015. The author explores the two foundations on which the ISLLC Standards rest, academic press and supportive community. Design/methodology/approach:…

  9. The Ford Foundation at Work. Philanthropic Choices, Methods, and Styles.

    ERIC Educational Resources Information Center

    Magat, Richard

    The procedures and philosophy of the Ford Foundation are outlined in this book, which reviews the past and present practices of the philanthropic organization and illustrates the processes through which more than $1,000,000 in funding support is annually dispensed. Case studies are presented that reflect the vast extent of the foundation's…

  10. Supporting Low Income Neighborhood Organizations. A Guide for Community Foundations.

    ERIC Educational Resources Information Center

    Mayer, Steven E.; Scheie, David M.

    Community foundations can be effective vehicles for channeling support to low income neighborhood organizations. This document comprises a guide for community foundations to help them develop their grantmaking and programming skills and to connect with other elements of community leadership. Chapter 1, "Why Support Low Income Neighborhood…

  11. 26 CFR 53.4942(b)-1 - Operating foundations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... qualitative, rather than a strictly quantitative, one. Therefore, if the foundation maintains a significant... particular discipline or substantive area (such as scientific or medical research, social work, education, or... scientific research projects which are under the general direction and supervision of the foundation)....

  12. 26 CFR 53.4942(b)-1 - Operating foundations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... qualitative, rather than a strictly quantitative, one. Therefore, if the foundation maintains a significant... particular discipline or substantive area (such as scientific or medical research, social work, education, or... scientific research projects which are under the general direction and supervision of the foundation)....

  13. The President's Review and Annual Report 1973. The Rockefeller Foundation.

    ERIC Educational Resources Information Center

    Rockefeller Foundation, New York, NY.

    This document presents the President's review and annual report of the activities of the Rockefeller Foundation for 1973. Following an overall review of the activities, emphasis is placed on specific activities the Foundation is involved with, including: conquest of hunger, problems of population, university development, conflict in international…

  14. Public health. Gates Foundation on big funding spree.

    PubMed

    Hagmann, M

    2000-08-11

    The Bill and Melinda Gates Foundation dished up $200 million in grants for scientists in various fields late last month, including research into malaria and tuberculosis. The foundation kicked off its spending spree in mid-July at the XIII International AIDS Conference in Durban, South Africa, by announcing several AIDS/HIV-related grants totaling $90 million.

  15. 2011 Policies, Practices, and Composition of Institutionally Related Foundation Boards

    ERIC Educational Resources Information Center

    Association of Governing Boards of Universities and Colleges, 2011

    2011-01-01

    Based on a 2011 survey, this report is intended to provide foundation staff and boards, as well as administrators and boards of public colleges, universities, and university systems, with an understanding of common foundation governance practices and board composition. Among other things, this report demonstrates the enormous heterogeneity of…

  16. 49 CFR 229.57 - Foundation brake gear.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Foundation brake gear. 229.57 Section 229.57..., DEPARTMENT OF TRANSPORTATION RAILROAD LOCOMOTIVE SAFETY STANDARDS Safety Requirements Brake System § 229.57 Foundation brake gear. A lever, rod, brake beam, hanger, or pin may not be worn through more than 30...

  17. 49 CFR 229.57 - Foundation brake gear.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Foundation brake gear. 229.57 Section 229.57..., DEPARTMENT OF TRANSPORTATION RAILROAD LOCOMOTIVE SAFETY STANDARDS Safety Requirements Brake System § 229.57 Foundation brake gear. A lever, rod, brake beam, hanger, or pin may not be worn through more than 30...

  18. 49 CFR 229.57 - Foundation brake gear.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Foundation brake gear. 229.57 Section 229.57..., DEPARTMENT OF TRANSPORTATION RAILROAD LOCOMOTIVE SAFETY STANDARDS Safety Requirements Brake System § 229.57 Foundation brake gear. A lever, rod, brake beam, hanger, or pin may not be worn through more than 30...

  19. 49 CFR 229.57 - Foundation brake gear.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Foundation brake gear. 229.57 Section 229.57..., DEPARTMENT OF TRANSPORTATION RAILROAD LOCOMOTIVE SAFETY STANDARDS Safety Requirements Brake System § 229.57 Foundation brake gear. A lever, rod, brake beam, hanger, or pin may not be worn through more than 30...

  20. 49 CFR 229.57 - Foundation brake gear.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Foundation brake gear. 229.57 Section 229.57..., DEPARTMENT OF TRANSPORTATION RAILROAD LOCOMOTIVE SAFETY STANDARDS Safety Requirements Brake System § 229.57 Foundation brake gear. A lever, rod, brake beam, hanger, or pin may not be worn through more than 30...

  1. A Social Foundations Approach to Educational Policy Analysis.

    ERIC Educational Resources Information Center

    Washburn, David E.

    Educators hold varied opinions about the nature of the social foundations of education. The social-foundations perspective generally characterizes education as an integrated multidisciplinary approach to the study of education, which focuses on the relationship among social conditions, values, and educational policies. This paper supports the…

  2. Teacher Training and Educational Foundations: A Plea for Discontent.

    ERIC Educational Resources Information Center

    Beyer, Landon E.; Zeichner, Kenneth M.

    1982-01-01

    Discontent over educational foundations in teacher education programs is felt because: (1) a vocational approach to teacher education is viewed as neutral process; (2) this approach does not recognize political and ideological commitments that guide public schools and teacher education programs; and (3) foundations are seen as contentious because…

  3. Increasing the Value of Evaluation to Philanthropic Foundations

    ERIC Educational Resources Information Center

    Greenwald, Howard P.

    2013-01-01

    This article synthesizes interview data from evaluation directors and top executives of philanthropic foundations on how evaluation might better advance their missions. In key informant interviews, respondents commented on the purposes of evaluation from the foundation's perspective, challenges to effective evaluation, and the means by which…

  4. New York State Health Foundation: integrating mental health and substance abuse care.

    PubMed

    Isaacs, Stephen; Jellinek, Paul; Martinez Garcel, Jacqueline; Hunt, Kelly A; Bunch, Will

    2013-10-01

    Roughly half of all people with severe mental disorders also have substance abuse problems. Yet their care is fragmented: They are treated by either the mental health system or the substance abuse system. In New York State only 10 percent of them receive evidence-based treatment for both conditions. Beginning in 2007 the New York State Health Foundation and two state agencies--the Office of Mental Health and the Office of Alcoholism and Substance Abuse Services--began collaborating on ways to integrate the treatment of people with co-occurring disorders. The state agencies removed financial and regulatory barriers to integrated treatment. The foundation provided funding to establish the Center for Excellence in Integrated Care. The center's goal: provide hands-on assistance in implementing best practices to at least half of the state's 1,200 mental health and substance abuse treatment clinics. An evaluation found that the percentage of clinics using best practices doubled after the regulatory and financial changes and the center's intervention. This illustrates the potential that foundations, governments, and nonprofits, working collaboratively, have to improve the care of a neglected and difficult-to-serve population.

  5. Foundation-industry relationships--a new business model joint-venture philanthropy in therapy development.

    PubMed

    Bartek, Ronald J

    2014-01-01

    The business model for medical therapy development has changed drastically. Large companies that once conducted their own Research and Development (R&D) and funded all the preclinical studies, all phases of clinical development and marketing of the products are increasingly turning to others for more and more of the earlier work in hopes of being able to in-license a de-risked program well downstream, take it through the final phases of clinical development and into the marketplace. This new paradigm has required patient-advocacy foundations, especially in the rare-disease space, to become far more effective in building relationships with all the players along the therapy-development pathway -- academic scientists, government agencies, other foundations with overlapping interests, biotechs, small biopharmaceutical entities and even the larger industry companies. From the perspective of the patient-advocacy community, these increasingly essential public-private partnerships have taken on the nature of what could be called joint-venture philanthropy and involve a broad spectrum of collaborations and financial relationships between foundations and industry partners that are not without concerns about potential conflicts of interest.

  6. The Healthy Weight Commitment Foundation Pledge

    PubMed Central

    Ng, Shu Wen; Slining, Meghan M.; Popkin, Barry M.

    2014-01-01

    Corporate voluntary pledges to improve the health of Americans have not been held to either explicit measurable outcomes or a framework for independent evaluation. The Healthy Weight Commitment Foundation (HWCF), whose members include 16 of the nation’s leading consumer packaged goods (CPG) food and beverage manufacturers, voluntarily pledged to collectively sell 1 trillion fewer calories in the U.S. marketplace by 2012 (against a 2007 baseline), and sell 1.5 trillion fewer calories by 2015. This paper presents the findings of an independent evaluation of the 2012 HWCF marketplace pledge, conducted in 2013. The 16 HWCF companies collectively sold approximately 6.4 trillion fewer calories (−10.6%) in 2012 than in the baseline year of 2007. Taking into account population changes over the 5-year period of 2007–2012, CPG caloric sales from brands included in the HWCF pledge declined by an average of 78 kcals/capita/day. CPG caloric sales from non-HWCF national brands during the same period declined by 11 kcals/capita/day, but there was little change in calories from private label products. Thus, the total reduction in CPG caloric sales between 2007 and 2012 was 87 kcals/capita/day. This independent evaluation is the first to evaluate food industry compliance with its calorie reduction pledges and to assess how sales from the CPG food and beverage sector are changing. An accompanying paper investigates the extent to which the HWCF pledge affected household-level changes in CPG calories purchased, controlling for important economic and sociodemographic factors affecting household food purchases over this period. PMID:25240967

  7. Human nature: a foundation for palliative care.

    PubMed

    Whelton, Beverly J B

    2008-04-01

    The Aristotelian-Thomist philosopher holds that human intellectual knowledge is possible because of the order in the world and natural human capacities. It is the position of this paper that there is a shared human form or nature that unites all humanity as members of the same kind. Moral treatment is due to every human being because they are human, and is not based upon expression of abilities. Humans have substantial dynamic existence in the world, an existence which overflows in expressive relationships. As both patient and health professional are human, human nature forms the natural foundation of health care. This paper looks towards human nature for moral guidance. The therapeutic relationship is seen as a part of the interpersonal moral space formed by human relationality, which tends towards community - in this case, the healthcare system. The therapeutic relationship is also a source of moral responsibility, as illness makes the patient vulnerable, while knowledge and nursing capacities generate in the nurse a duty to care. Nursing theory serves to connect philosophical reflection and nursing practice. Imogene King's conceptual system and theory of Goal Attainment is the theory that follows from the perspective of human person being presented. This synthesis of philosophy and theory is developed with the goal of shedding light on healthcare decisions in palliative care. The article concludes with the acknowledgement that the complexity of contextualized individual decisions requires the insight and discipline of the moral practitioner, and provides some thoughts on how education, development, and refinement transform an individual into a nurse. PMID:18336705

  8. Interiors of small bodies: foundations and perspectives

    NASA Astrophysics Data System (ADS)

    Binzel, Richard P.; A'Hearn, Michael; Asphaug, Erik; Barucci, M. Antonella; Belton, Michael; Benz, Willy; Cellino, Alberto; Festou, Michel C.; Fulchignoni, Marcello; Harris, Alan W.; Rossi, Alessandro; Zuber, Maria T.

    2003-06-01

    With the surface properties and shapes of solar system small bodies (comets and asteroids) now being routinely revealed by spacecraft and Earth-based radar, understanding their interior structure represents the next frontier in our exploration of these worlds. Principal unknowns include the complex interactions between material strength and gravity in environments that are dominated by collisions and thermal processes. Our purpose for this review is to use our current knowledge of small body interiors as a foundation to define the science questions which motivate their continued study: In which bodies do "planetary" processes occur? Which bodies are "accretion survivors", i.e., bodies whose current form and internal structure are not substantially altered from the time of formation? At what characteristic sizes are we most likely to find "rubble-piles", i.e., substantially fractured (but not reorganized) interiors, and intact monolith-like bodies? From afar, precise determinations of newly discovered satellite orbits provide the best prospect for yielding masses from which densities may be inferred for a diverse range of near-Earth, main-belt, Trojan, and Kuiper belt objects. Through digital modeling of collision outcomes, bodies that are the most thoroughly fractured (and weak in the sense of having almost zero tensile strength) may be the strongest in the sense of being able to survive against disruptive collisions. Thoroughly fractured bodies may be found at almost any size, and because of their apparent resistance to disruptive collisions, may be the most commonly found interior state for small bodies in the solar system today. Advances in the precise tracking of spacecraft are giving promise to high-order measurements of the gravity fields determined by rendezvous missions. Solving these gravity fields for uniquely revealing internal structure requires active experiments, a major new direction for technological advancement in the coming decade. We note the

  9. The Healthy Weight Commitment Foundation Pledge

    PubMed Central

    Ng, Shu Wen; Popkin, Barry M.

    2014-01-01

    Context An independent evaluation of the Healthy Weight Commitment Foundation (HWCF) marketplace pledge found that the participating companies met and exceeded their interim 2012 sales reduction pledge. Evidence acquisition This follow-up study conducted in 2013 used purchase data from 2000–2012 among U.S. households with children and compared trends in calorie purchases of HWCF, non-HWCF name brands, and private label (PL) products in the pre-pledge period (2000–2007) and the post-pledge period (2008–2012); controlled for potential effects of concurrent changes in demographic and economic factors, including the Great Recession and food prices; and assessed whether the HWCF marketplace pledge was associated with reductions in consumer packaged goods (CPG) calorie purchases by households with children. Evidence synthesis There has been a significant per capita decline in average daily CPG caloric purchases between 2000 and 2012 among households with children from all brand categories. Based on pre-pledge trends, declines in CPG caloric purchases were already occurring. However, post-pledge reductions in calories purchased from HWCF brands were less than expected, and reductions in calories purchased from non-HWCF name brands and PLs were greater than expected after economic, sociodemographic, and secular factors were accounted for. Conclusions If the 16 HWCF companies had been able to maintain their pre-pledge trajectory, there should have been an additional 42 kcals/capita/day reduction in calories purchased from HWCF products in 2012 among households with children. A lack of change in total CPG calories purchased between 2011 and 2012 calls into question the sustainability of the decline and a need for continued monitoring. PMID:25240968

  10. Considerations and foundations for Botnet simulation

    NASA Astrophysics Data System (ADS)

    Stytz, Martin R.; Banks, Sheila B.

    2009-04-01

    "Botnets", or "bot armies", are large groups of remotely controlled malicious software. Bot armies pose one of the most serious security threats to all networks. Botnets, remotely controlled and operated by botmasters or botherders, can launch massive denial of service attacks, multiple penetration attacks, or any other malicious network activity on a massive scale. While bot army activity has, in the past, been limited to fraud, blackmail, and other forms of criminal activity, their potential for causing large-scale damage to the entire internet; for launching large-scale, coordinated attacks on government computers and networks; and for large-scale, coordinated data gathering from thousands of users and computers on any network has been underestimated. This paper will not discuss how to build bots but the threats they pose. In a "botnet" or "bot army", computers can be used to spread spam, launch denial-of-service attacks against Web sites, conduct fraudulent activities, and prevent authorized network traffic from traversing the network. In this paper, we examine the need for botnet defense training within existing simulation environments and present our suggestions for the capabilities needed for training systems for botnet activities. In this paper we discuss botnet technology and review the technologies that underlie this threat to network, information, and computer security. The second section contains background information about bot armies and key foundational bot technologies. The third section presents a discussion of the types of attacks that botnets can conduct, defenses against them and our suggestions for simulating botnet activities, including suggested message formats for distributing bot simulation commands and for distributing information needed to simulate both the effects of bot attacks and defensive responses to bot attacks. The fourth section contains a summary and suggestions for future research.

  11. Fractional modeling of Pasternak-type viscoelastic foundation

    NASA Astrophysics Data System (ADS)

    Cai, Wei; Chen, Wen; Xu, Wenxiang

    2016-06-01

    In this paper, we propose a fractional Pasternak-type foundation model to characterize the time-dependent properties of the viscoelastic foundation. With varying fractional orders, the proposed model can govern the traditional Winkler model, Pasternak model, and viscoelastic model. We take the four-edge simply supported rectangular thin plate as an example to analyze the viscoelastic foundation reaction, and obtain the solution of the new governing equation. Theoretical results show that the fractional order has a dramatic influence on the deflection and bending moment. It can be further concluded that the softer foundation will become more time-dependent. Subsequently, the difference between fractional Pasternak-type and Winkler foundation model is presented in this work. The existence of constrained boundary is found to definitely affect deflection and bending moment. Such phenomenon, known as the wall effect, is deeply discussed.

  12. Shifting liberal and conservative attitudes using moral foundations theory.

    PubMed

    Day, Martin V; Fiske, Susan T; Downing, Emily L; Trail, Thomas E

    2014-12-01

    People's social and political opinions are grounded in their moral concerns about right and wrong. We examine whether five moral foundations--harm, fairness, ingroup, authority, and purity--can influence political attitudes of liberals and conservatives across a variety of issues. Framing issues using moral foundations may change political attitudes in at least two possible ways: (a) Entrenching: Relevant moral foundations will strengthen existing political attitudes when framing pro-attitudinal issues (e.g., conservatives exposed to a free-market economic stance) and (b) Persuasion: Mere presence of relevant moral foundations may also alter political attitudes in counter-attitudinal directions (e.g., conservatives exposed to an economic regulation stance). Studies 1 and 2 support the entrenching hypothesis. Relevant moral foundation-based frames bolstered political attitudes for conservatives (Study 1) and liberals (Study 2). Only Study 2 partially supports the persuasion hypothesis. Conservative-relevant moral frames of liberal issues increased conservatives' liberal attitudes.

  13. Shifting liberal and conservative attitudes using moral foundations theory.

    PubMed

    Day, Martin V; Fiske, Susan T; Downing, Emily L; Trail, Thomas E

    2014-12-01

    People's social and political opinions are grounded in their moral concerns about right and wrong. We examine whether five moral foundations--harm, fairness, ingroup, authority, and purity--can influence political attitudes of liberals and conservatives across a variety of issues. Framing issues using moral foundations may change political attitudes in at least two possible ways: (a) Entrenching: Relevant moral foundations will strengthen existing political attitudes when framing pro-attitudinal issues (e.g., conservatives exposed to a free-market economic stance) and (b) Persuasion: Mere presence of relevant moral foundations may also alter political attitudes in counter-attitudinal directions (e.g., conservatives exposed to an economic regulation stance). Studies 1 and 2 support the entrenching hypothesis. Relevant moral foundation-based frames bolstered political attitudes for conservatives (Study 1) and liberals (Study 2). Only Study 2 partially supports the persuasion hypothesis. Conservative-relevant moral frames of liberal issues increased conservatives' liberal attitudes. PMID:25286912

  14. On the instability of offshore foundations: theory and mechanism

    NASA Astrophysics Data System (ADS)

    Gao, FuPing; Li, JinHui; Qi, WenGang; Hu, Cun

    2015-12-01

    As the offshore engineering moving from shallow to deep waters, the foundation types for fixed and floating platforms have been gradually evolving to minimize engineering costs and structural risks in the harsh offshore environments. Particular focus of this paper is on the foundation instability and its failure mechanisms as well as the relevant theory advances for the prevailing foundation types in both shallow and deep water depths. Piles, spudcans, gravity bases, suction caissons, and plate anchors are detailed in this paper. The failure phenomena and mechanisms for each type of foundations are identified and summarized, respectively. The theoretical approaches along with sophisticated empirical solutions for the bearing capacity problems are then presented. The major challenges are from flow-structure-soil coupling processes, rigorous constitutive modeling of cyclic behaviors of marine sediments, and the spatial variability of soil properties for large-spreading structures. Further researches are suggested to reveal the instability mechanisms for underpinning the evolution of offshore foundations.

  15. Load Measurement on Foundations of Rockfall Protection Systems.

    PubMed

    Volkwein, Axel; Kummer, Peter; Bitnel, Hueseyin; Campana, Lorenzo

    2016-01-01

    Rockfall protection barriers are connected to the ground using steel cables fixed with anchors and foundations for the steel posts. It is common practice to measure the forces in the cables, while to date measurements of forces in the foundations have been inadequately resolved. An overview is presented of existing methods to measure the loads on the post foundations of rockfall protection barriers. Addressing some of the inadequacies of existing approaches, a novel sensor unit is presented that is able to capture the forces acting on post foundations in all six degrees of freedom. The sensor unit consists of four triaxial force sensors placed between two steel plates. To correctly convert the measurements into the directional forces acting on the foundation a special in-situ calibration procedure is proposed that delivers a corresponding conversion matrix. PMID:26840315

  16. Load Measurement on Foundations of Rockfall Protection Systems

    PubMed Central

    Volkwein, Axel; Kummer, Peter; Bitnel, Hueseyin; Campana, Lorenzo

    2016-01-01

    Rockfall protection barriers are connected to the ground using steel cables fixed with anchors and foundations for the steel posts. It is common practice to measure the forces in the cables, while to date measurements of forces in the foundations have been inadequately resolved. An overview is presented of existing methods to measure the loads on the post foundations of rockfall protection barriers. Addressing some of the inadequacies of existing approaches, a novel sensor unit is presented that is able to capture the forces acting on post foundations in all six degrees of freedom. The sensor unit consists of four triaxial force sensors placed between two steel plates. To correctly convert the measurements into the directional forces acting on the foundation a special in-situ calibration procedure is proposed that delivers a corresponding conversion matrix. PMID:26840315

  17. A qualitative investigation of Foundation Year 2 doctors' views on the European Working Time Directive.

    PubMed

    Duncan, Myanna; Haslam, Cheryl

    2015-01-01

    PURPOSE - The purpose of this paper is to examine the personal views and experiences of Foundation Year 2 doctors operating under the European Working Time Directive (EWTD). DESIGN/METHODOLOGY/APPROACH - In total, 36 Foundation Year 2 doctors from a single UK-based Deanery participated in this semistructured interview study. FINDINGS - Findings indicated that Foundation doctors typically welcomed a regulation of working hours, but reported frustration at the manner in which the Directive had been implemented. Participants reported concerns at reducing hours by removing out-of-hours working in order to meet EWTD requirements. Out-of-hours shifts were highly valued owing to their increased opportunities for autonomous clinical decision making. By contrast, day-shifts were regarded as heavily administrative in nature and were perceived as service provision. Foundation doctors discussed the unique nature of the out-of-hours working period which appeared to provide specific learning opportunities as doctors draw on time management and prioritisation skills. ORIGINALITY/VALUE - Given the challenges the EWTD presents, careful rota planning is essential. First, the authors would encourage the restructuring of day-shift work to provide a greater emphasis on hands-on skills experience in a supportive, supervised environment. Second, where possible, Foundation doctors might benefit from the opportunity to engage in some out-of-hours working, such as with multi-professional "Hospital at Night" teams. Third, the authors would encourage junior doctor involvement in rota design and planning which may increase their perceived autonomy and therefore buy-in of working practices. PMID:25970530

  18. The Impact of Team-Based Learning on a Foundational Pharmacokinetics Course

    PubMed Central

    2012-01-01

    Objective. To assess the impact of team-based learning (TBL) in a foundational pharmacokinetics course. Design. The course was arranged into 5 modules based on the TBL format. Each module contained preclass preparation; readiness-assurance process; and in-class, clinical cases. Survey instruments on professionalism and attitudes of team learning were administered pre- and post-course. Assessment. Examination grades focused at the evaluation/creation level were significantly higher in the TBL format compared with the previous year. Professionalism scores increased over the course of the semester, particularly in altruism and honesty. Other measures of team-learning attitudes significantly increased over time, although there was no change in major subscales. End-of-semester course evaluations showed improvements in active engagement and in various areas of skill development. Conclusion. The TBL format can be used successfully in a foundational pharmacokinetics course to increase higher levels of learning, team-learning skills, and professionalism in pharmacy students. PMID:22438603

  19. The Familiar Foundation and the Fuller Sense: Ethics Consultation and Narrative

    PubMed Central

    Nelson, Craig

    2012-01-01

    As clinical ethicists and ethics committee members, we strive to create the ideal situation for moral conversation and ethical reflection. Using both the familiar foundation and the fuller sense, the ethicist and ethics committee are aided in participating more fruitfully in a process of resolution. The familiar foundation represents a body of knowledge that ethics consultants and ethics committees should thoroughly understand. In addition, there is a depth of analysis found in the fuller sense, through narrative, that sharpens ethical focus and enables richer understanding of the patient's situation in life. In using both tools, patients and families are better served than they would be relying on either tool by itself. Stakeholders and their relationships become more clearly assessed and individuals more effectively discover their own legitimate position. This can mean a more thorough representation of moral problems, a deeper understanding of all parties involved, and a greater opportunity to help parties better understand themselves and each other. PMID:22745620

  20. Simplified technique for rebuilding a post and core foundation with a preexisting crown: a case report.

    PubMed

    Signore, Antonio; Benedicenti, Stefano; Kaitsas, Vassilios; Barone, Michele

    2010-03-01

    A 58-year-old patient presented with a dislodged crown and post and core on the maxillary right first premolar. After endodontic retreatment, two tapered glass-fiber posts were adhesively cemented. The core foundation was completed by retrofitting the existing crown with a self-curing composite core material. The intaglio surface was lubricated with petroleum jelly, which allowed for easy removal of the crown. Adequate cement thickness was ensured by the finishing procedures of the core buildup that respected the existing tooth margins. The glass-fiber posts and composite buildup provided adequate stability and retention to the original casting. The technique described in this short clinical report enables clinicians to rebuild a post-and-core foundation using the existing crown without the original die or its replica in a simple and time-saving way.

  1. "The Trampoline Tree and the Swamp Monster with 18 Heads": Outdoor Play in the Foundation Stage and Foundation Phase

    ERIC Educational Resources Information Center

    Waller, Tim

    2007-01-01

    This paper considers pedagogy and outdoor play in the early years. The particular focus is on the specific features and benefits of outdoor play in the Foundation Stage (England) and Foundation Phase (Wales). The paper will draw on current international literature and evidence from outdoor learning constructed in an ongoing research project in two…

  2. Genomic and personalized medicine: foundations and applications.

    PubMed

    Ginsburg, Geoffrey S; Willard, Huntington F

    2009-12-01

    The last decade has witnessed a steady embrace of genomic and personalized medicine by senior government officials, industry leadership, health care providers, and the public. Genomic medicine, which is the use of information from genomes and their derivatives (RNA, proteins, and metabolites) to guide medical decision making-is a key component of personalized medicine, which is a rapidly advancing field of health care that is informed by each person's unique clinical, genetic, genomic, and environmental information. As medicine begins to embrace genomic tools that enable more precise prediction and treatment disease, which include "whole genome" interrogation of sequence variation, transcription, proteins, and metabolites, the fundamentals of genomic and personalized medicine will require the development, standardization, and integration of several important tools into health systems and clinical workflows. These tools include health risk assessment, family health history, and clinical decision support for complex risk and predictive information. Together with genomic information, these tools will enable a paradigm shift to a comprehensive approach that will identify individual risks and guide clinical management and decision making, all of which form the basis for a more informed and effective approach to patient care. DNA-based risk assessment for common complex disease, molecular signatures for cancer diagnosis and prognosis, and genome-guided therapy and dose selection are just among the few important examples for which genome information has already enabled personalized health care along the continuum from health to disease. In addition, information from individual genomes, which is a fast-moving area of technological development, is spawning a social and information revolution among consumers that will undoubtedly affect health care decision making. Although these and other scientific findings are making their way from the genome to the clinic, the full

  3. Modern Foundations of Light Transport Simulation

    NASA Astrophysics Data System (ADS)

    Lessig, Christian

    Light transport simulation aims at the numerical computation of the propagation of visible electromagnetic energy in macroscopic environments. In this thesis, we develop the foundations for a modern theory of light transport simulation, unveiling the geometric structure of the continuous theory and providing a formulation of computational techniques that furnishes remarkably efficacy with only local information. Utilizing recent results from various communities, we develop the physical and mathematical structure of light transport from Maxwell's equations by studying a lifted representation of electromagnetic theory on the cotangent bundle. At the short wavelength limit, this yields a Hamiltonian description on six-dimensional phase space, with the classical formulation over the space of "positions and directions" resulting from a reduction to the five-dimensional cosphere bundle. We establish the connection between light transport and geometrical optics by a non-canonical Legendre transform, and we derive classical concepts from radiometry, such as radiance and irradiance, by considering measurements of the light energy density. We also show that in idealized environments light transport is a Lie-Poisson system for the group of symplectic diffeomorphisms, unveiling a tantalizing similarity between light transport and fluid dynamics. Using Stone's theorem, we also derive a functional analytic description of light transport. This bridges the gap to existing formulations in the literature and naturally leads to computational questions. We then address one of the central challenges for light transport simulation in everyday environments with scattering surfaces: how are efficient computations possible when the light energy density can only be evaluated pointwise? Using biorthogonal and possibly overcomplete bases formed by reproducing kernel functions, we develop a comprehensive theory for computational techniques that are restricted to pointwise information

  4. Hanford Waste Treatment Complex Foundation for Success

    SciTech Connect

    BOSTON, H.L.

    2001-02-01

    provisions. The RPP is managed as a single, integrated Waste Treatment Complex. A RPP management team consisting of ORP, Tank Farm Contractor (CH2M HILL Hanford Group, Inc.), and the Waste Treatment and Immobilization Plant (WTP) Contractor (Bechtel Washington) execute the mission. The role each organization plays in laying out the foundations for success of the Waste Treatment Complex will be further identified in the paper.

  5. Rebuilding mathematics on a quantum logical foundation

    NASA Astrophysics Data System (ADS)

    DeJonghe, Richard J., III

    We construct a rich first-order quantum logic which generalizes the standard classical predicate logic used in the development of virtually all of modern mathematics, and we use this quantum logic to build the foundations of a new quantum mathematics. First, we prove both soundness and completeness for the quantum logic we develop, and also prove a powerful new completeness result which heretofore had been known to hold for classical, but not quantum, first-order logic. We then use our quantum logic to develop multiple areas of mathematics, including abstract algebra, axiomatic set theory, and arithmetic. In some preliminary investigations into quantum mathematics, Dunn found that the Peano axioms for arithmetic yield the same theorems using either classical or quantum logic. We prove a similar result for certain classes of abstract algebras, and then show that Dunn's result is not generic by presenting examples of quantum monoids, groups, lattices, vector spaces, and operator algebras, all which differ from their classical counterparts. Moreover, we find natural classes of quantum lattices, vector spaces, and operator algebras which all have a beautiful inter-relationship, and make some preliminary investigations into using these structures as a basis for a new mathematical formulation of quantum mechanics. We also develop a quantum set theory (equivalent to ZFC under classical logic) which is far more tractable than quantum set theory previously developed. We then use this set theory to construct a quantum version of the natural numbers, and develop an arithmetic of these numbers based upon an alternative to Peano's axioms (which avoids Dunn's theorem). Surprisingly, we find that these "quantum natural numbers" satisfy our arithmetical axioms if and only if the underlying truth values form a modular lattice, giving a new arithmetical characterization of this important lattice-theoretic property. Finally, we show that these numbers have a natural interpretation as

  6. Diverse therapeutic targets and biomarkers for Alzheimer's disease and related dementias: report on the Alzheimer's Drug Discovery Foundation 2012 International Conference on Alzheimer's Drug Discovery

    PubMed Central

    2013-01-01

    The Alzheimer's Drug Discovery Foundation's 13th International Conference on Alzheimer's Drug Discovery was held on 10-11 September 2012 in Jersey City, NJ, USA. This meeting report provides an overview of Alzheimer's Drug Discovery Foundation-funded programs, ranging from novel biomarkers to accelerate clinical development to drug-discovery programs with a focus on targets related to neuroprotection, mitochondrial function, apolipoprotein E and vascular biology. PMID:23374760

  7. University cardiology clinic.

    PubMed

    Borozanov, V

    2013-01-01

    In distant 1972, within framework of the Internal Clinic, a cardiologic department was organized which was soon, on 29.XII.1974, transformed into the Cardiology Clinic, later the Institute for Heart Diseases, and in 2008 was renamed the University Cardiology Clinic. The greater part of its foundation was possible owing to Prof. Dimitar Arsov and Prof. Radovan Percinkovski, who was the clinic's first director in the period from 1974 to 1984. In 1985, the Clinic moved into its own new building, and in that way was physically detached from the Internal Clinics. Until its move to the new building, the Clinic functioned in the Internal Clinics building, organized as an outpatient polyclinic and inpatient infirmary department with clinical beds, a coronary intensive care unit and a haemodynamics laboratory equipped with the most modern equipment of that time. Today the Clinic functions through two integral divisions: an inpatient infirmary department which comprises an intensive coronary care unit and fourteen wards which altogether have 139 clinical beds, and the diagnostic centre which comprises an emergency clinic and day hospital, a communal and consultative outpatients' clinic functioning on a daily basis, through which some 300-350 patients pass every day, and diagnostic laboratories with a capacity of nearly 100 non-invasive and 20-30 invasive diagnostic procedures daily. The Clinic is a teaching base, and its doctors are educators of students at the Medical, Dental and Pharmacy Faculties, and also of students at the High School for Nurses and X-ray technicians, but also for those in Internal Medicine and especially Cardiology. The Clinic is also a base for scientific Masters' and post-doctoral studies, and such higher degrees are achieved not only by doctors who work here, but also by doctors from Medical Centres both in the country and abroad. Doctors working in this institution publish widely, not only a great number of books and monographs, but also original

  8. University cardiology clinic.

    PubMed

    Borozanov, V

    2013-01-01

    In distant 1972, within framework of the Internal Clinic, a cardiologic department was organized which was soon, on 29.XII.1974, transformed into the Cardiology Clinic, later the Institute for Heart Diseases, and in 2008 was renamed the University Cardiology Clinic. The greater part of its foundation was possible owing to Prof. Dimitar Arsov and Prof. Radovan Percinkovski, who was the clinic's first director in the period from 1974 to 1984. In 1985, the Clinic moved into its own new building, and in that way was physically detached from the Internal Clinics. Until its move to the new building, the Clinic functioned in the Internal Clinics building, organized as an outpatient polyclinic and inpatient infirmary department with clinical beds, a coronary intensive care unit and a haemodynamics laboratory equipped with the most modern equipment of that time. Today the Clinic functions through two integral divisions: an inpatient infirmary department which comprises an intensive coronary care unit and fourteen wards which altogether have 139 clinical beds, and the diagnostic centre which comprises an emergency clinic and day hospital, a communal and consultative outpatients' clinic functioning on a daily basis, through which some 300-350 patients pass every day, and diagnostic laboratories with a capacity of nearly 100 non-invasive and 20-30 invasive diagnostic procedures daily. The Clinic is a teaching base, and its doctors are educators of students at the Medical, Dental and Pharmacy Faculties, and also of students at the High School for Nurses and X-ray technicians, but also for those in Internal Medicine and especially Cardiology. The Clinic is also a base for scientific Masters' and post-doctoral studies, and such higher degrees are achieved not only by doctors who work here, but also by doctors from Medical Centres both in the country and abroad. Doctors working in this institution publish widely, not only a great number of books and monographs, but also original

  9. Virtuous capital: what foundations can learn from venture capitalists.

    PubMed

    Letts, C W; Ryan, W; Grossman, A

    1997-01-01

    U.S. foundations and nonprofits work diligently on behalf of society's most needy and yet report that progress is slow and social problems persist. How can they learn to be more effective with their limited resources? Foundations should consider expanding their mission from investing only in program innovation to investing in the organizational needs of nonprofit organizations as well. Their overemphasis on program design has meant deteriorating organizational capacity at many nonprofits. If foundations are to help nonprofits be assured of making payroll, paying the rent, or buying a much-needed computer, they must develop hands-on partnering skills. Venture capital firms offer a helpful benchmark. In addition to putting up capital, they closely monitor the companies in which they have invested, provide management support and stay involved long enough to see the company become strong. If foundation officers familiarize themselves with such practices, they can begin to build organizational capacity in the nonprofit sector. Foundations can hire organizational experts to assist grantees; they can lengthen grant terms to allow nonprofits to build up organization strengths; and they can create new classes of grants that allow for organizational effectiveness. Nonprofits in turn should articulate their organizational needs when applying for grants; they should apply to foundations known for longer-term grants; and they should create plans that justify long-term support from foundations.

  10. The emotional foundations of high moral intelligence.

    PubMed

    Narvaez, Darcia

    2010-01-01

    Moral intelligence is grounded in emotion and reason. Neuroscientific and clinical research illustrate how early life co-regulation with caregivers influences emotion, cognition, and moral character. Triune ethics theory (Narvaez, 2008) integrates neuroscientific, evolutionary, and developmental findings to explain differences in moral functioning, identifying security, engagement, and imagination ethics that can be dispositionally fostered by experience during sensitive periods, but also situationally triggered. Mature moral functioning relies on the integration of emotion, intuition, and reasoning, which come together in adaptive ethical expertise. Moral expertise can be cultivated in organizations using the integrative ethical education model.

  11. Innovative Retrofit Insulation Strategies for Concrete Masonry Foundations

    SciTech Connect

    Huelman, P.; Goldberg, L.; Jacobson, R.

    2015-05-01

    Basements in climates 6 and 7 can account for a fraction of a home's total heat loss when fully conditioned. Such foundations are a source of moisture, with convection in open block cavities redistributing water from the wall base, usually when heating. Even when block cavities are capped, the cold foundation concrete can act as a moisture source for wood rim joist components that are in contact with it. Because below-grade basements are increasingly used for habitable space, cold foundation walls pose challenges for moisture contribution, energy use, and occupant comfort.

  12. Simplifying transformations for the analysis of shallow foundations on sand

    SciTech Connect

    Butterfield, R.; Gottardi, G.

    1995-12-31

    Prediction of the ultimate load capacity of shallow sand-supported foundations is a fundamental offshore engineering problem. The paper demonstrates how the complete (V,H,M) failure envelope of such foundations, represented by a system of parabolas and rotated ellipses, can be transformed into a single unit circle by referring the applied loads to an origin located below the foundation centerline. The conjugate transformation applied to the corresponding displacements generates a symmetry amongst them, for symmetrical load paths, not otherwise apparent. Extensive, model-scale, experimental data is presented which provides convincing support for the unit circle failure envelope.

  13. 1. TUCKERTON WIRELESS, RADIO ROAD, PERSPECTIVE VIEW OF CONCRETE FOUNDATION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. TUCKERTON WIRELESS, RADIO ROAD, PERSPECTIVE VIEW OF CONCRETE FOUNDATION OF RADIO STANTION WITH WIRELESS BUILDING AND SMOKESTACK IN BACKGROUND, LOOKING NORTH - Town of Tuckerton, U.S. Highway 9 & County Road 539, Tuckerton, Ocean County, NJ

  14. 11. Detail view southwest foundation remnants and singlestory flat roof ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Detail view southwest foundation remnants and single-story flat roof building associated with the Clark Cotton Mill/Columbia Narrow Fabrics Co. Factory - Shannock Village, Main Street, North Shannock Road, & West Shannock Road, Richmond (historical), Providence County, RI

  15. 44. DETAIL VIEW LOOKING EAST AT THE FOUNDATION FOR SLAG ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    44. DETAIL VIEW LOOKING EAST AT THE FOUNDATION FOR SLAG CRUSHER, A DEVICE USED TO REMOVE HARDENED SLAG FROM STEEL LADLES. - John A. Roebling's Sons Company, Kinkora Works, Support Systems, Roebling, Burlington County, NJ

  16. 5. Detail view of masonry foundations and flue openings for ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Detail view of masonry foundations and flue openings for Jamaican Train. - Hacienda Azucarera El Coto, Sugar Mill Ruins, .5 Mi. SW of Rt. 347 Bridge Over Guanajibo River, San German, San German Municipio, PR

  17. Floor Plans Foundation Plan at Bedrock and Subgrade Level ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Floor Plans - Foundation Plan at Bedrock and Subgrade Level Plan - Marshall Space Flight Center, F-1 Engine Static Test Stand, On Route 565 between Huntsville and Decatur, Huntsville, Madison County, AL

  18. 53. VIEW OF ROCK FOUNDATIONS AIR CLEANED FOR MONOLITHS 1722, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    53. VIEW OF ROCK FOUNDATIONS AIR CLEANED FOR MONOLITHS 17-22, INTERMEDIATE WALL, LOOKING NORTH Photograph No. 12840. September 10, 1948 - Upper Mississippi River 9-Foot Channel Project, Lock & Dam 27, Granite City, Madison County, IL

  19. Shifting Liberal and Conservative Attitudes Using Moral Foundations Theory

    PubMed Central

    Day, Martin V.; Fiske, Susan T.; Downing, Emily L.; Trail, Thomas E.

    2016-01-01

    People’s social and political opinions are grounded in their moral concerns about right and wrong. We examine whether five moral foundations—harm, fairness, ingroup, authority, and purity—can influence political attitudes of liberals and conservatives across a variety of issues. Framing issues using moral foundations may change political attitudes in at least two possible ways: 1. Entrenching: relevant moral foundations will strengthen existing political attitudes when framing pro-attitudinal issues (e.g., conservatives exposed to a free-market economic stance). 2. Persuasion: mere presence of relevant moral foundations may also alter political attitudes in counter-attitudinal directions (e.g., conservatives exposed to an economic regulation stance). Studies 1 and 2 support the entrenching hypothesis. Relevant moral foundation-based frames bolstered political attitudes for conservatives (Study 1) and liberals (Study 2). Only Study 2 partially supports the persuasion hypothesis. Conservative-relevant moral frames of liberal issues increased conservatives’ liberal attitudes. PMID:25286912

  20. 7. DETAIL VIEW OF SOUTHWESTERN CORNER OF BRIDGE AND FOUNDATION, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. DETAIL VIEW OF SOUTHWESTERN CORNER OF BRIDGE AND FOUNDATION, SHOWING TRACES OF CONCRETE POURING DURING CONSTRUCTION AND EMBEDDED IRON HARDWARE ON OUTER FACE OF PARAPET. FACING NORTHEAST - Brevard Bridge, Spanning Westland Run at Ullom Road, Export, Washington County, PA

  1. Preface of the special issue quantum foundations: information approach.

    PubMed

    D'Ariano, Giacomo Mauro; Khrennikov, Andrei

    2016-05-28

    This special issue is based on the contributions of a group of top experts in quantum foundations and quantum information and probability. It enlightens a number of interpretational, mathematical and experimental problems of quantum theory. PMID:27091161

  2. SHENANDOAHDIVES (MAYFLOWER) MINE PORTAL SITE, LOOKING WEST. NOTE FOUNDATION AT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    SHENANDOAH-DIVES (MAYFLOWER) MINE PORTAL SITE, LOOKING WEST. NOTE FOUNDATION AT RIGHT AND RADIATOR AT LOWER LEFT, BOTH REMNANTS OF THE DORMITORY. - Shenandoah-Dives Mill, 135 County Road 2, Silverton, San Juan County, CO

  3. View of the foundation of the former warehouse (Feature 6), ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of the foundation of the former warehouse (Feature 6), view to the southeast - Orphan Lode Mine, North of West Rim Road between Powell Point and Maricopa Point, South Rim, Grand Canyon Village, Coconino County, AZ

  4. View of the foundation of the former warehouse (Feature 6), ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of the foundation of the former warehouse (Feature 6), view to the west-northwest - Orphan Lode Mine, North of West Rim Road between Powell Point and Maricopa Point, South Rim, Grand Canyon Village, Coconino County, AZ

  5. 10. VIEW TO SOUTHEAST, SAMPLING BUILDING, FOUNDATION, WATER TOWER, AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. VIEW TO SOUTHEAST, SAMPLING BUILDING, FOUNDATION, WATER TOWER, AND SKINNER SALT ROASTERS. - Vanadium Corporation of America (VCA) Naturita Mill, 3 miles Northwest of Naturita, between Highway 141 & San Miguel River, Naturita, Montrose County, CO

  6. 95. View of foundation plant looking east showing one of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    95. View of foundation plant looking east showing one of the four cylinders completed in the midstream tower known as Pier 3. - Carquinez Bridge, Spanning Carquinez Strait at Interstate 80, Vallejo, Solano County, CA

  7. View of foundation, looking southeast. Note tennis courts in background ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of foundation, looking southeast. Note tennis courts in background facing southeast, see HABS No. CA-2716 - Presidio of San Francisco, Officers' Vehicles Garage, 1055 General Kennedy Avenue, Letterman Hospital Complex, San Francisco, San Francisco County, CA

  8. View of foundation, looking south. Note tennis courts in background ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of foundation, looking south. Note tennis courts in background facing south, see HABS no. CA-2716 - Presidio of San Francisco, Officers' Vehicles Garage, 1055 General Kennedy Avenue, Letterman Hospital Complex, San Francisco, San Francisco County, CA

  9. General view of concrete foundation rail for Pintle Crane at ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of concrete foundation rail for Pintle Crane at marine railway, completed. 14th Naval District Photo Collection Item No. 4640 - U.S. Naval Base, Pearl Harbor, Exterior Cranes, Waterfront Crane Track System, Pearl City, Honolulu County, HI

  10. Typical Window, Interior Wall Paint Sequence, Wall Section, and Foundation ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Typical Window, Interior Wall Paint Sequence, Wall Section, and Foundation Sections - Civilian Conservation Corps (CCC) Camp NP-5-C, Barracks No. 5, CCC Camp Historic District at Chapin Mesa, Cortez, Montezuma County, CO

  11. 9. PHOTOCOPY, FOUNDATION AND FLOORING PLANS FOR ADMINISTRATION BUILDING. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. PHOTOCOPY, FOUNDATION AND FLOORING PLANS FOR ADMINISTRATION BUILDING. - NIKE Missile Base SL-40, Administration Building, East central portion of base, southeast of Mess Hall, northeast of HIPAR Equipment Building, Hecker, Monroe County, IL

  12. 4. EXTERIOR CONTEXT OF BUILDING 220 WITH FOUNDATION OF 224 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. EXTERIOR CONTEXT OF BUILDING 220 WITH FOUNDATION OF 224 IN THE FOREGROUND, LOOKING NORTH. - Mill Valley Air Force Station, Mess Hall, East Ridgecrest Boulevard, Mount Tamalpais, Mill Valley, Marin County, CA

  13. 7. FOUNDATIONS OF FLUME NO. 8, EXPOSED. SCE negative no. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. FOUNDATIONS OF FLUME NO. 8, EXPOSED. SCE negative no. 3077, January 26, 1916. Photograph by G. Haven Bishop. - Santa Ana River Hydroelectric System, Flumes & Tunnels below Sandbox, Redlands, San Bernardino County, CA

  14. 42. FOUNDATIONS TAIL RACE, ETC., POWER HOUSE SANTA ANA ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    42. FOUNDATIONS - TAIL RACE, ETC., POWER HOUSE SANTA ANA RIVER NO. 2, EDISON ELECTRIC CO., NOV. 3, 1904. SCE drawing no. 5393. - Santa Ana River Hydroelectric System, SAR-2 Powerhouse, Redlands, San Bernardino County, CA

  15. 9. UNIDENTIFIED STRUCTURE FOUNDATIONS IN RELATION TO THE NORTH TRAINING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. UNIDENTIFIED STRUCTURE FOUNDATIONS IN RELATION TO THE NORTH TRAINING WALL, LOOKING TO THE EAST. - Oakland Harbor Training Walls, Mouth of Federal Channel to Inner Harbor, Oakland, Alameda County, CA

  16. Everett Weinreb, Photographer, April 1989 FOUNDATION DETAIL REVEALED AS RESULT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Everett Weinreb, Photographer, April 1989 FOUNDATION DETAIL REVEALED AS RESULT OF HOUSE DEMOLITION - Irvine Ranch Agricultural Headquarters, Boyd Tenant House, Southeast of Intersection of San Diego & Santa Ana Freeways, Irvine, Orange County, CA

  17. 33. CONSTRUCTION OF FOUNDATION FOR ORIGINAL CROSSCUT DIESEL PLANT BUILDING, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    33. CONSTRUCTION OF FOUNDATION FOR ORIGINAL CROSSCUT DIESEL PLANT BUILDING, LATER ENLARGED TO HOUSE STEAM GENERATING EQUIPMENT. November 23, 1937 - Crosscut Steam Plant, North side Salt River near Mill Avenue & Washington Street, Tempe, Maricopa County, AZ

  18. 1. VIEW OF THE FOUNDATION OF BUILDING 107, MOTORCYCLE HOBBY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. VIEW OF THE FOUNDATION OF BUILDING 107, MOTORCYCLE HOBBY SHOP, LOOKING EAST-NORTHEAST. - Mill Valley Air Force Station, Motorcycle Shop, East Ridgecrest Boulevard, Mount Tamalpais, Mill Valley, Marin County, CA

  19. 12. Photocopy of engineering drawing. LAUNCHING FACILITY BLOCKHOUSE: FOUNDATION PLAN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Photocopy of engineering drawing. LAUNCHING FACILITY BLOCKHOUSE: FOUNDATION PLAN AND SECTIONS-STRUCTURAL, 1964 (ORIGINALLY APPROVED MARCH 1954). - Cape Canaveral Air Station, Launch Complex 17, Facility 28401, East end of Lighthouse Road, Cape Canaveral, Brevard County, FL

  20. 6. CANNERY PILINGS Foundation of a portion of the cannery ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. CANNERY PILINGS Foundation of a portion of the cannery over water. Crumbling cement footings and decomposing pilings make portions of this area unsafe. - Hovden Cannery, 886 Cannery Row, Monterey, Monterey County, CA

  1. 1. OIL HOUSE FOUNDATIONS, DIKE, AND PORTION OF SOUTH FRONT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. OIL HOUSE FOUNDATIONS, DIKE, AND PORTION OF SOUTH FRONT OF MAIN ASSEMBLY PLANT. VIEW TO WEST. - Ford Motor Company Long Beach Assembly Plant, Oil House, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  2. 17. SPRINGHOUSE, SOUTHWEST SIDE; NOTE BROKEN GRANITE FOUNDATION FROM SURROUNDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. SPRINGHOUSE, SOUTHWEST SIDE; NOTE BROKEN GRANITE FOUNDATION FROM SURROUNDING HILLSIDES. - Hondius Water Line, 1.6 miles Northwest of Park headquarters building & 1 mile Northwest of Beaver Meadows entrance station, Estes Park, Larimer County, CO

  3. Preface of the special issue quantum foundations: information approach

    PubMed Central

    2016-01-01

    This special issue is based on the contributions of a group of top experts in quantum foundations and quantum information and probability. It enlightens a number of interpretational, mathematical and experimental problems of quantum theory. PMID:27091161

  4. 9. May 20, 1963 SEED BUILDING FOUNDATION WALLS Under Construction. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. May 20, 1963 SEED BUILDING FOUNDATION WALLS Under Construction. Looking southeast showing north and west walls of Machinery Shed - Tucson Plant Material Center, Machinery Shed, 3241 North Romero Road, Tucson, Pima County, AZ

  5. 2. Detail of tower foundation with lightning transfer wire, southeast ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Detail of tower foundation with lightning transfer wire, southeast corner - Cold Mountain Fire Lookout Station, Lookout Tower, Krassel District, Frank Church River of No Return Wilderness, Dixie, Idaho County, ID

  6. Four-square. Practice profitability stands on four foundations.

    PubMed

    Mefford, Daniel D

    2003-09-01

    A medical practice's profitability stands on four legs: physician productivity, accounts receivable, overhead costs and ancillary revenue. The author describes where weakness can occur in each of these foundations and how to remedy such structural defects.

  7. ARCTIC FOUNDATIONS, INC. FREEZE BARRIER TECHNOLOGY; INNOVATIVE TECHNOLOGY EVALUATION REPORT

    EPA Science Inventory

    Arctic Foundations, Inc. (AFI), of Anchorage, Alaska has developed a freeze barrier technology designed to prevent the migration of contaminants in groundwater by completely isolating contaminant source areas until appropriate remediation techniques can be applied. With this tech...

  8. ARCTIC FOUNDATIONS, INC. FREEZE BARRIER SYSTEM - SITE TECHNOLOGY CAPSULE

    EPA Science Inventory

    Arctic Foundations, Inc. (AFI), of Anchorage, Alaska has developed a freeze barrier technology designed to prevent the migration of contaminants in groundwater by completely isolating contaminant source areas until appropriate remediation techniques can be applied. With this tec...

  9. Electrical resistivity imaging for unknown bridge foundation depth determination

    NASA Astrophysics Data System (ADS)

    Arjwech, Rungroj

    Unknown bridge foundations pose a significant safety risk due to stream scour and erosion. Records from older structures may be non-existent, incomplete, or incorrect. Nondestructive and inexpensive geophysical methods have been identified as suitable to investigate unknown bridge foundations. The objective of the present study is to apply advanced 2D electrical resistivity imaging (ERI) in order to identify depth of unknown bridge foundations. A survey procedure is carried out in mixed terrain water and land environments with rough topography. A conventional resistivity survey procedure is used with the electrodes installed on the stream banks. However, some electrodes must be adapted for underwater use. Tests were conducted in one laboratory experimentation and at five field experimentations located at three roadway bridges, a geotechnical test site, and a railway bridge. The first experimentation was at the bridges with the smallest foundations, later working up in size to larger drilled shafts and spread footings. Both known to unknown foundations were investigated. The geotechnical test site is used as an experimental site for 2D and 3D ERI. The data acquisition is carried out along 2D profile with a linear array in the dipole-dipole configuration. The data collections have been carried out using electrodes deployed directly across smaller foundations. Electrodes are deployed in proximity to larger foundations to image them from the side. The 2D ERI can detect the presence of a bridge foundation but is unable to resolve its precise shape and depth. Increasing the spatial extent of the foundation permits better image of its shape and depth. Using electrode < 1 m to detect a slender foundation < 1 m in diameter is not feasible. The 2D ERI method that has been widely used for land surface surveys presently can be adapted effectively in water-covered environments. The method is the most appropriate geophysical method for determination of unknown bridge foundations

  10. The brain's emotional foundations of human personality and the Affective Neuroscience Personality Scales.

    PubMed

    Davis, Kenneth L; Panksepp, Jaak

    2011-10-01

    Six of the primary-process subcortical brain emotion systems - SEEKING, RAGE, FEAR, CARE, GRIEF and PLAY - are presented as foundational for human personality development, and hence as a potentially novel template for personality assessment as in the Affective Neurosciences Personality Scales (ANPS), described here. The ANPS was conceptualized as a potential clinical research tool, which would help experimentalists and clinicians situate subjects and clients in primary-process affective space. These emotion systems are reviewed in the context of a multi-tiered framing of consciousness spanning from primary affect, which encodes biological valences, to higher level tertiary (thought mediated) processing. Supporting neuroscience research is presented along with comparisons to Cloninger's Temperament and Character Inventory and the Five Factor Model (FFM). Suggestions are made for grounding the internal structure of the FFM on the primal emotional systems recognized in affective neuroscience, which may promote substantive dialog between human and animal research traditions. Personality is viewed in the context of Darwinian "continuity" with the inherited subcortical brain emotion systems being foundational, providing major forces for personality development in both humans and animals, and providing an affective infrastructure for an expanded five factor descriptive model applying to normal and clinical human populations as well as mammals generally. Links with ontogenetic and epigenetic models of personality development are also presented. Potential novel clinical applications of the CARE maternal-nurturance system and the PLAY system are also discussed.

  11. A narrative review of the theoretical foundations of loneliness.

    PubMed

    Tzouvara, Vasiliki; Papadopoulos, Chris; Randhawa, Gurch

    2015-07-01

    Loneliness has been found to relate to a wide range of harmful health outcomes. The adverse effects of loneliness upon people's lives emphasise the importance of understanding its nature and process. A number of theoretical and conceptual foundations have been proposed by scholars and are discussed and reflected upon in this article. The discussion and understanding of loneliness theoretical foundations provide useful insights toward the interpretation of its occurrence.

  12. IET. Coupling station and track foundations under construction. Camera facing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    IET. Coupling station and track foundations under construction. Camera facing northerly. Four-rail track foundations lead to coupling station. Service leads from there will go through opening for "quick connects" below. Retaining wall under construction will separate earthen shielding of control building (out of view to right) from coupling station and track. Date: October 20, 1954. INEEL negative no. 12550 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

  13. The New York Stem Cell Foundation. Interview with Susan Solomon.

    PubMed

    Solomon, Susan

    2012-11-01

    We caught up with Susan Solomon, Co-Founder of The New York Stem Cell Foundation, to discuss the role of the Foundation in facilitating some of the top advances in stem cell science in recent years. Susan L Solomon is Chief Executive Officer and Co-Founder of The New York Stem Cell Foundation (NYSCF), a nonprofit organization established in 2005 to accelerate cures through stem cell research. A longtime healthcare advocate, Susan is a founding member and current President of New Yorkers for the Advancement of Medical Research, is on the Executive Committee for the Alliance for Regenerative Medicine, and she has been a member of the Board of Directors of the Juvenile Diabetes Research Foundation, New York Chapter. Susan was also a member of the Strategic Planning Committee of the Empire State Stem Cell Board. In March 2008, Susan received a New York State Women of Excellence Award from the Governor of New York. In September 2008, she received the Triumph Award from the Brooke Ellison Foundation for her work in establishing NYSCF. Prior to founding NYSCF, Susan, an attorney, spent much of her career building businesses. She established and ran Solomon Partners LLC to provide strategic management consulting to corporations, cultural institutions, foundations and nonprofit organizations. She has also held executive positions at MacAndrews and Forbes Holdings and MMG Patricof and Co. She was the founding Chief Executive Officer of Sothebys.com and was President of Sony Worldwide Networks. PMID:23210823

  14. He who pays the piper: foundations, the medical profession, and medical education reform.

    PubMed

    Brown, E R

    1980-01-01

    The development of modern medical education was shaped by the medical profession's own reform strategies and by material and ideological support from the corporate class. This article examines how the Rockefeller medical philanthropies, the largest single source of funds for medical education reform from 1910 through the 1930s, forced the adoption of a specific reform--full-time clinical faculty--to make medicine serve the needs of capitalist society rather than the interests of the medical profession. Memorandums and letters from archival files demonstrate that foundation leaders believed the full-time plan would separate medical schools from the grip of practitioner-dominated medical societies, bringing all medical faculty under the control of foundations and university boards of trustees. This policy was to be a first step in rationalizing medical care and distributing the technical benefits and social-control functions of medicine to all segments of the population. The author traces the development of the full-time plan, its adoption as foundation policy, and the struggle over its implementation.

  15. Aplastic Anemia & MDS International Foundation (AA&MDSIF): bone marrow failure disease scientific symposium 2012.

    PubMed

    Savage, Sharon A; Pulsipher, Michael A; Romano, Alessandra; Berlyne, Deborah

    2013-07-01

    Aplastic anemia (AA), myelodysplastic syndrome (MDS), and paroxysmal nocturnal hemoglobinuria (PNH) are rare disorders of bone marrow failure. Once considered distinct entities, these three diseases are now believed to have overlapping pathophysiologies. The Aplastic Anemia and MDS International Foundation, a nonprofit organization that supports patients and families living with bone marrow failure disorders, sponsored a scientific symposium in Bethesda, MD, in March 2012. This report summarizes the symposium presentations by 30 of the world's leading AA, MDS, and PNH researchers on recent findings, current areas of controversy, and recommendations for basic and clinical research to advance the field.

  16. Seismic performance of an existing bridge with scoured caisson foundation

    NASA Astrophysics Data System (ADS)

    Chang, Kuo-Chun; Sung, Yu-Chi; Liu, Kuang-Yen; Wang, Ping-Hsiung; Lee, Zheng-Kuan; Lee, Lu-Sheng; Witarto

    2014-08-01

    This paper presents in-situ seismic performance tests of a bridge before its demolition due to accumulated scouring problem. The tests were conducted on three single columns and one caisson-type foundation. The three single columns were 1.8 m in diameter, reinforced by 30-D32 longitudinal reinforcements and laterally hooped by D16 reinforcements with spacing of 20 cm. The column height is 9.54 m, 10.59 m and 10.37 m for Column P2, P3, and P4, respectively. Column P2 had no exposed foundation and was subjected to pseudo-dynamic tests with peak ground acceleration of 0.32 g first, followed by one cyclic loading test. Column P3 was the benchmark specimen with exposed length of 1.2 m on its foundation. The exposed length for Column P4 was excavated to 4 m, approximately 1/3 of the foundation length, to study the effect of the scouring problem to the column performance. Both Column P3 and Column P4 were subjected to cyclic loading tests. Based on the test results, due to the large dimension of the caisson foundation and the well graded gravel soil type that provided large lateral resistance, the seismic performance among the three columns had only minor differences. Lateral push tests were also conducted on the caisson foundation at Column P5. The caisson was 12 m long and had circular cross-sections whose diameters were 5 m in the upper portion and 4 m in the lower portion. An analytical model to simulate the test results was developed in the OpenSees platform. The analytical model comprised nonlinear flexural elements as well as nonlinear soil springs. The analytical results closely followed the experimental test results. A parametric study to predict the behavior of the bridge column with different ground motions and different levels of scouring on the foundation are also discussed.

  17. The Clinical Use of Hypnotic Regression and Progression in Psychotherapy.

    ERIC Educational Resources Information Center

    Goldberg, Bruce

    1990-01-01

    Discusses concept of time in therapy, presenting theoretical and clinical foundations to illustrate the validity of guiding patients into past lives and future lifetimes through hypnosis to resolve self-defeating sequences. (Author/TE)

  18. High Performance Slab-on-Grade Foundation Insulation Retrofits

    SciTech Connect

    Goldberg, Louise F.; Mosiman, Garrett E.

    2015-09-01

    ?A more accurate assessment of SOG foundation insulation energy savings than traditionally possible is now feasible. This has been enabled by advances in whole building energy simulation with 3-dimensional foundation modelling integration at each time step together with an experimental measurement of the site energy savings of SOG foundation insulation. Ten SOG insulation strategies were evaluated on a test building to identify an optimum retrofit insulation strategy in a zone 6 climate (Minneapolis, MN). The optimum insulation strategy in terms of energy savings and cost effectiveness consisted of two components: (a) R-20 XPS insulation above grade, and, (b) R-20 insulation at grade (comprising an outer layer of R-10 insulation and an interior layer of R-12 poured polyurethane insulation) tapering to R-10 XPS insulation at half the below-grade wall height (the lower half of the stem wall was uninsulated). The optimum insulation strategy was applied to single and multi-family residential buildings in climate zone 4 - 7. The highest site energy savings of 5% was realized for a single family home in Duluth, MN, and the lowest savings of 1.4 % for a 4-unit townhouse in Richmond, VA. SOG foundation insulation retrofit simple paybacks ranged from 18 to 47 years. There are other benefits of SOG foundation insulation resulting from the increase in the slab surface temperatures. These include increased occupant thermal comfort, and a decrease in slab surface condensation particularly around the slab perimeter.

  19. Lipid droplets may lay a spacial foundation for vasculogenic mimicry formation in hepatocellular carcinoma.

    PubMed

    Li, Yue; Cai, Weiwei; Yi, Qingqing; Xie, Fengshan; Liu, Yanling; Du, Bin; Feng, Lei; Qiu, Liying

    2014-07-01

    Vasculogenic mimicry is a highly patterned vascular channel distinguished from the endothelium-dependent blood vessel. Vasculogenic mimicry is lined by highly aggressive tumor cells, and is associated with tumor grade, invasion and metastasis, and poor clinical prognosis. Much attention has been focused on the signaling pathways and the tumor microenvironment needed for vasculogenic mimicry formation, however, the studies on the spacial foundation for vasculogenic mimicry formation are limited. There are many lipid droplets in hepatocellular carcinoma due to steatosis, while increased numbers of lipid droplets also have been reported in many other neoplastic processes. The role of lipid droplets in tumor is still unclear. Based on the similar structural and morphological characteristics between vasculogenic mimicry and lipid droplet, we speculate that the lipid droplets may lay a spacial foundation for vasculogenic mimicry formation by a way of "space placeholder" in HCC. Experimental data and limited clinical literatures support the hypothesis to a certain degree. This hypothesis may provide a new idea for the study of vasculogenic mimicry and also provide a new direction for the functional study of lipid droplets in tumor.

  20. On the Hilbert-Huang Transform Theoretical Foundation

    NASA Technical Reports Server (NTRS)

    Kizhner, Semion; Blank, Karin; Huang, Norden E.

    2004-01-01

    The Hilbert-Huang Transform [HHT] is a novel empirical method for spectrum analysis of non-linear and non-stationary signals. The HHT is a recent development and much remains to be done to establish the theoretical foundation of the HHT algorithms. This paper develops the theoretical foundation for the convergence of the HHT sifting algorithm and it proves that the finest spectrum scale will always be the first generated by the HHT Empirical Mode Decomposition (EMD) algorithm. The theoretical foundation for cutting an extrema data points set into two parts is also developed. This then allows parallel signal processing for the HHT computationally complex sifting algorithm and its optimization in hardware.

  1. Foundational tuning: how infants' attention to speech predicts language development.

    PubMed

    Vouloumanos, Athena; Curtin, Suzanne

    2014-01-01

    Orienting biases for speech may provide a foundation for language development. Although human infants show a bias for listening to speech from birth, the relation of a speech bias to later language development has not been established. Here, we examine whether infants' attention to speech directly predicts expressive vocabulary. Infants listened to speech or non-speech in a preferential listening procedure. Results show that infants' attention to speech at 12 months significantly predicted expressive vocabulary at 18 months, while indices of general development did not. No predictive relationships were found for infants' attention to non-speech, or overall attention to sounds, suggesting that the relationship between speech and expressive vocabulary was not a function of infants' general attentiveness. Potentially ancient evolutionary perceptual capacities such as biases for conspecific vocalizations may provide a foundation for proficiency in formal systems such language, much like the approximate number sense may provide a foundation for formal mathematics.

  2. Design guide for frost-protected shallow foundations

    SciTech Connect

    1994-10-01

    Frost-protected shallow foundations (FPSFs) offer a proven technology designed to substantially lower construction costs in colder climates, enhancing housing affordability for families in many parts of the United States. This document provides step-by-step procedures to assist building professionals in designing and laying a slab- on-grade FPSF. FPSFs save money over conventional designs by requiring less excavation to construct a frost-proof foundation. It is specially insulated along its perimeter to raise the temperature of the surrounding ground and decrease frost penetration, thus allowing for the construction of a substantially shallower foundation. The FPSF is considered standard practice for homes in Scandinavia, where 40 years of field testing has proven it to be economical to construct, durable, and energy efficient. HUD strongly encourages wide spread adoption of FPSF technology in the United States and its incorporation into major model building codes.

  3. High-Performance Slab-on-Grade Foundation Insulation Retrofits

    SciTech Connect

    Goldberg, Louise F.; Mosiman, Garrett E.

    2015-09-01

    A more accurate assessment of slab-on-grade foundation insulation energy savings than traditionally possible is now feasible. This has been enabled by advances in whole building energy simulation with 3-dimensional foundation modelling integration at each time step together with an experimental measurement of the site energy savings of SOG foundation insulation. Ten SOG insulation strategies were evaluated on a test building to identify an optimum retrofit insulation strategy in a zone 6 climate (Minneapolis, MN). The optimum insulation strategy in terms of energy savings and cost effectiveness consisted of two components: (a) R-20 XPS insulation above grade, and, (b) R-20 insulation at grade (comprising an outer layer of R-10 insulation and an interior layer of R-12 poured polyurethane insulation) tapering to R-10 XPS insulation at half the below-grade wall height (the lower half of the stem wall was uninsulated).

  4. Gates Foundation donates $25 million for AIDS vaccine.

    PubMed

    1999-05-01

    The International AIDS Vaccine Initiative (IAVI) received a $25 million five-year grant from Bill and Melinda Gates through the William H. Gates Foundation. This is the largest gift seen in the AIDS epidemic, and will allow IAVI to more than double vaccine development efforts. IAVI is currently developing two potential vaccines, hopes to study three others, and is working with the business community to insure that a successful vaccine is affordable in developing countries. With 16,000 new infections occurring daily, a vaccine is seen as the most effective way to stop the epidemic. The William H. Gates Foundation had donated $1.5 million to IAVI and $100 million for programs to speed the delivery of vaccines to children in poor countries. Internet addresses are included for both IAVI and the William H. Gates Foundation.

  5. Solving the Beam Bending Problem with an Unilateral Winkler Foundation

    NASA Astrophysics Data System (ADS)

    Machalová, Jitka; Netuka, Horymír

    2011-09-01

    Our work is going to deal with the bending of a beam resting on an unilateral elastic foundation and develops further the ideas from the article [5]. In some cases the beam has fixed connection with the foundation. Such problems are linear. However there are applications where the beam is not connected with the foundation. This so-called unilateral case represents an interesting nonlinear problem and cannot be solved by easy means. We propose here first a new formulation of this problem which is based upon the idea of a decomposition. This way we can convert the usual variational formulation of our problem to a saddle-point formulation. In the second part of this paper we will deal with a numerical solution using the finite element method. The system of equations for the saddle point is nonlinear and nondifferentiable. It can be handled by the transformation to a complementarity problem which is solved by the nonsmooth Newton method.

  6. Maximum information entropy: a foundation for ecological theory.

    PubMed

    Harte, John; Newman, Erica A

    2014-07-01

    The maximum information entropy (MaxEnt) principle is a successful method of statistical inference that has recently been applied to ecology. Here, we show how MaxEnt can accurately predict patterns such as species-area relationships (SARs) and abundance distributions in macroecology and be a foundation for ecological theory. We discuss the conceptual foundation of the principle, why it often produces accurate predictions of probability distributions in science despite not incorporating explicit mechanisms, and how mismatches between predictions and data can shed light on driving mechanisms in ecology. We also review possible future extensions of the maximum entropy theory of ecology (METE), a potentially important foundation for future developments in ecological theory.

  7. 77 FR 35271 - Safety Zone; NOAA Vessel Rueben Lasker Launch, Marinette, WI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-13

    .... SUPPLEMENTARY INFORMATION: Table of Acronyms DHS Department of Homeland Security FR Federal Register NPRM Notice..., WI AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard is establishing a temporary safety zone on the Menominee River in Marinette, WI. This zone is intended to restrict...

  8. Content Analysis as a Foundation for Programmatic Research in Communication

    PubMed Central

    Slater, Michael D.

    2013-01-01

    Previous arguments that content analyses provide the descriptive foundation for media effects research (McLeod & Reeves, 1980) are extended to include that content analyses can provide a sound and useful foundation for programmatic research by individual communication scientists. I discuss examples from my own work and from that of colleagues in communication and related disciplines. Use of messages sampled and coded in a content analysis in combination with survey data sets or as stimuli in experiments are highlighted. The particular potential for employing larger numbers of randomly sampled messages in experimental designs, and, with use of appropriate statistical methods, being able to generalize to populations of messages, is described. PMID:23914276

  9. Generating a foundation for Concurrent Engineering. Final report

    SciTech Connect

    Christensen, N.C.

    1997-03-01

    Both Concurrent Engineering and the Agile Enterprise require as a foundation the low cost, timely sharing of information. Described is a cost-effective way to generate this foundation from the product data International Standard 10303 (informally called STEP). Also described is a prototype implementation. AlliedSignal, Federal Manufacturing and Technologies (FM and T), was the first facility in the world to manufacture a mechanical part using the then draft international standard (DIS) ISO 10303 STEP. The Advanced Manufacturing Development System (AMDS) enabled this accomplishment.

  10. Using a Foundational Ontology for Reengineering a Software Enterprise Ontology

    NASA Astrophysics Data System (ADS)

    Perini Barcellos, Monalessa; de Almeida Falbo, Ricardo

    The knowledge about software organizations is considerably relevant to software engineers. The use of a common vocabulary for representing the useful knowledge about software organizations involved in software projects is important for several reasons, such as to support knowledge reuse and to allow communication and interoperability between tools. Domain ontologies can be used to define a common vocabulary for sharing and reuse of knowledge about some domain. Foundational ontologies can be used for evaluating and re-designing domain ontologies, giving to these real-world semantics. This paper presents an evaluating of a Software Enterprise Ontology that was reengineered using the Unified Foundation Ontology (UFO) as basis.

  11. Is Rorty’s Neopragmatism the “Real” Foundation of Medical Ethics: a Search for Foundational Principles

    PubMed Central

    Branch, William T

    2006-01-01

    Principlism, the predominate approach to bioethics, has no foundational principles. This absence of foundations reflects the general intellectual climate of postmodern relativism. Even America’s foremost public philosopher, Richard Rorty, whose pragmatism might suggest a philosophy of commonsense, seems to be swimming in the postmodern swamp. Alternatively, principlism’s architects, Beauchamp and Childress, suggest a constantly evolving reflective equilibrium with some basis in common morality as a workable framework for twenty-first century bioethics. The flaw in their approach is failure to conform to real doctors’ and patients’ experiences. Real doctors adopt a scientific paradigm that assumes an objective reality. Patients experience real suffering and seek effective cures, treatments, palliation and solace. The foundation of medical ethics should be that doctors altruistically respond to their patients’ suffering using scientifically acceptable modalities. Compassion, caring, and respect for human dignity are needed as guides in addition to justice, beneficence, nonmaleficence and respect for autonomy. PMID:18528478

  12. 22 CFR 1003.5 - Access to personal information from Inter-American Foundation records.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...-American Foundation records. 1003.5 Section 1003.5 Foreign Relations INTER-AMERICAN FOUNDATION RULES... Foundation records. (a) The Inter-American Foundation will promulgate regulations, as necessary, to insure..., as applicable. (b) Any individual will be notified upon request if any Inter-American...

  13. 26 CFR 1.509(a)-1 - Definition of private foundation.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 7 2013-04-01 2013-04-01 false Definition of private foundation. 1.509(a)-1...) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Private Foundations § 1.509(a)-1 Definition of private foundation. In general. Section 509(a) defines the term private foundation to mean any domestic or...

  14. 22 CFR 1003.5 - Access to personal information from Inter-American Foundation records.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...-American Foundation records. 1003.5 Section 1003.5 Foreign Relations INTER-AMERICAN FOUNDATION RULES... Foundation records. (a) The Inter-American Foundation will promulgate regulations, as necessary, to insure..., as applicable. (b) Any individual will be notified upon request if any Inter-American...

  15. 26 CFR 301.7454-2 - Burden of proof in foundation manager, etc. cases.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 18 2012-04-01 2012-04-01 false Burden of proof in foundation manager, etc... Actions by the United States § 301.7454-2 Burden of proof in foundation manager, etc. cases. (a) Foundation manager. In any proceeding involving the issue whether a foundation manager as defined in...

  16. 22 CFR 1003.5 - Access to personal information from Inter-American Foundation records.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...-American Foundation records. 1003.5 Section 1003.5 Foreign Relations INTER-AMERICAN FOUNDATION RULES... Foundation records. (a) The Inter-American Foundation will promulgate regulations, as necessary, to insure..., as applicable. (b) Any individual will be notified upon request if any Inter-American...

  17. 26 CFR 1.6033-3 - Additional provisions relating to private foundations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... foundations. 1.6033-3 Section 1.6033-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... to private foundations. (a) In general. The foundation managers (as defined in section 4946(b)) of... private foundation (as defined in section 509) the assets of which are at least $5,000 at any time...

  18. 26 CFR 1.509(b)-1 - Continuation of private foundation status.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 7 2011-04-01 2009-04-01 true Continuation of private foundation status. 1.509... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Private Foundations § 1.509(b)-1 Continuation of private foundation status. (a) In general. If an organization is a private foundation (within the...

  19. 22 CFR 1003.5 - Access to personal information from Inter-American Foundation records.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...-American Foundation records. 1003.5 Section 1003.5 Foreign Relations INTER-AMERICAN FOUNDATION RULES... Foundation records. (a) The Inter-American Foundation will promulgate regulations, as necessary, to insure..., as applicable. (b) Any individual will be notified upon request if any Inter-American...

  20. 26 CFR 1.6033-3 - Additional provisions relating to private foundations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... foundations. 1.6033-3 Section 1.6033-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... provisions relating to private foundations. (a) In general. The foundation managers (as defined in section... treated as) a private foundation (as defined in section 509) the assets of which are at least $5,000...

  1. 26 CFR 1.6033-3 - Additional provisions relating to private foundations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... foundations. 1.6033-3 Section 1.6033-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... provisions relating to private foundations. (a) In general. The foundation managers (as defined in section... treated as) a private foundation (as defined in section 509) the assets of which are at least $5,000...

  2. 26 CFR 1.6033-3 - Additional provisions relating to private foundations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... foundations. 1.6033-3 Section 1.6033-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... provisions relating to private foundations. (a) In general. The foundation managers (as defined in section... treated as) a private foundation (as defined in section 509) the assets of which are at least $5,000...

  3. 26 CFR 301.7454-2 - Burden of proof in foundation manager, etc. cases.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 18 2010-04-01 2010-04-01 false Burden of proof in foundation manager, etc... Actions by the United States § 301.7454-2 Burden of proof in foundation manager, etc. cases. (a) Foundation manager. In any proceeding involving the issue whether a foundation manager as defined in...

  4. 26 CFR 301.7454-2 - Burden of proof in foundation manager, etc. cases.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 18 2014-04-01 2014-04-01 false Burden of proof in foundation manager, etc... Actions by the United States § 301.7454-2 Burden of proof in foundation manager, etc. cases. (a) Foundation manager. In any proceeding involving the issue whether a foundation manager as defined in...

  5. 26 CFR 1.509(a)-1 - Definition of private foundation.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 7 2012-04-01 2012-04-01 false Definition of private foundation. 1.509(a)-1...) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Private Foundations § 1.509(a)-1 Definition of private foundation. In general. Section 509(a) defines the term private foundation to mean any domestic or...

  6. 26 CFR 1.509(b)-1 - Continuation of private foundation status.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 7 2013-04-01 2013-04-01 false Continuation of private foundation status. 1.509... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Private Foundations § 1.509(b)-1 Continuation of private foundation status. (a) In general. If an organization is a private foundation (within the...

  7. 26 CFR 1.509(a)-1 - Definition of private foundation.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 7 2014-04-01 2013-04-01 true Definition of private foundation. 1.509(a)-1...) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Private Foundations § 1.509(a)-1 Definition of private foundation. In general. Section 509(a) defines the term private foundation to mean any domestic or...

  8. 22 CFR 1003.5 - Access to personal information from Inter-American Foundation records.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...-American Foundation records. 1003.5 Section 1003.5 Foreign Relations INTER-AMERICAN FOUNDATION RULES... Foundation records. (a) The Inter-American Foundation will promulgate regulations, as necessary, to insure..., as applicable. (b) Any individual will be notified upon request if any Inter-American...

  9. 26 CFR 1.509(b)-1 - Continuation of private foundation status.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 7 2014-04-01 2013-04-01 true Continuation of private foundation status. 1.509... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Private Foundations § 1.509(b)-1 Continuation of private foundation status. (a) In general. If an organization is a private foundation (within the...

  10. 26 CFR 1.509(a)-1 - Definition of private foundation.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 7 2011-04-01 2009-04-01 true Definition of private foundation. 1.509(a)-1...) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Private Foundations § 1.509(a)-1 Definition of private foundation. In general. Section 509(a) defines the term private foundation to mean any domestic or...

  11. 26 CFR 1.6033-3 - Additional provisions relating to private foundations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... foundations. 1.6033-3 Section 1.6033-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... provisions relating to private foundations. (a) In general. The foundation managers (as defined in section... treated as) a private foundation (as defined in section 509) the assets of which are at least $5,000...

  12. 26 CFR 301.7454-2 - Burden of proof in foundation manager, etc. cases.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 18 2011-04-01 2011-04-01 false Burden of proof in foundation manager, etc... Actions by the United States § 301.7454-2 Burden of proof in foundation manager, etc. cases. (a) Foundation manager. In any proceeding involving the issue whether a foundation manager as defined in...

  13. 26 CFR 1.509(b)-1 - Continuation of private foundation status.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 7 2012-04-01 2012-04-01 false Continuation of private foundation status. 1.509... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Private Foundations § 1.509(b)-1 Continuation of private foundation status. (a) In general. If an organization is a private foundation (within the...

  14. 26 CFR 1.509(b)-1 - Continuation of private foundation status.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Continuation of private foundation status. 1.509... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Private Foundations § 1.509(b)-1 Continuation of private foundation status. (a) In general. If an organization is a private foundation (within the...

  15. 26 CFR 1.509(a)-1 - Definition of private foundation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Definition of private foundation. 1.509(a)-1...) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Private Foundations § 1.509(a)-1 Definition of private foundation. In general. Section 509(a) defines the term private foundation to mean any domestic or...

  16. 26 CFR 301.7454-2 - Burden of proof in foundation manager, etc. cases.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 18 2013-04-01 2013-04-01 false Burden of proof in foundation manager, etc... Actions by the United States § 301.7454-2 Burden of proof in foundation manager, etc. cases. (a) Foundation manager. In any proceeding involving the issue whether a foundation manager as defined in...

  17. The Infusion of Foundational Components into Pre-service Teacher Preparation Programs.

    ERIC Educational Resources Information Center

    Cole, Donna J.; McCormick, Theresa

    Most preservice teacher preparation schools include a tripartite set of courses--Foundations, Methods, and Practica. Since many Foundations educators currently are required to teach non-Foundations couses, they are in a situation to infuse many of the concepts and concentration areas of Foundations content into methodological and practicum…

  18. Is Foundation training producing competent doctors? What do Foundation trainees, educational supervisors and nurses in Scotland have to say?

    PubMed

    Wakeling, Judy; French, Fiona; Bagnall, Gellisse; McHardy, Ken

    2011-05-01

    The aim of this paper is to examine perceptions of Foundation Year trainees, consultants and senior nurses about the introduction of the Foundation Programme. Specifically, to examine whether Foundation trainees acquire appropriate skills, experience and responsibility. Semi-structured interviews were conducted with 23 F1 doctors, 22 F2 doctors, 23 consultants and 25 nurses from across Scotland in a broad range of specialties. In the summer of 2007 trainees, consultants and nurses broadly agreed that Foundation offers good experience but some issues were highlighted. Certain specialties were seen as offering insufficiently generic experience and consultants, in particular, were concerned that four-month rotations are too short. Frequent moving around for trainees was seen as detrimental for seeing cases through and continuity of care was now perceived to be provided by nurses and consultants rather than junior doctors. Levels of responsibility could vary widely from post to post and tended to be specialty-dependent. As a result, some F2s reported frustration that they were not given sufficient responsibility for their stage of training. Nights were recognized as a valuable learning opportunity and most trainees were supportive of night work being made available in F1 and F2. In conclusion, in order to maximize the possibilities of the Foundation years and ensure that trainees can meet the required Foundation competencies, specialties that offer narrow experience need to be matched with 'busy' specialties that can offer broader experience. Night work should be retained, but perhaps not introduced right at the start of F1. Trainees feeling that they are being given insufficient experience, particularly in the F2 year, need to be proactive in addressing this if possible. There is a perception among some consultants and nurses that a process of 'delayed skilling' is taking place, attributable more to reduced hours than Foundation per se. There is a need to follow

  19. An interview with Bill and Melinda Gates. Interviewed by Claire Pomeroy.

    PubMed

    Gates, Bill; Gates, Melinda

    2013-10-01

    Bill and Melinda Gates have led a profound transformation in the way we view the world's most pressing health concerns, looking for effective ways to improve the lives of millions of people. Claire Pomeroy, president of the Albert and Mary Lasker Foundation, spoke with them about their current concerns and plans to advance their agenda.

  20. Foundations of Science: Using Technology To Support Authentic Science Learning.

    ERIC Educational Resources Information Center

    Pryor, Amanda; Soloway, Elliot

    In a traditional science classroom, only a portion of students walk away with a genuine understanding of the material, and even fewer are able to apply the concepts they have learned to events in their own lives. Foundations of Science (FOS) was developed in a cooperative effort between the University of Michigan and the Ann Arbor public schools…