A Semantically Enabled Metadata Repository for Solar Irradiance Data Products
NASA Astrophysics Data System (ADS)
Wilson, A.; Cox, M.; Lindholm, D. M.; Nadiadi, I.; Traver, T.
2014-12-01
The Laboratory for Atmospheric and Space Physics, LASP, has been conducting research in Atmospheric and Space science for over 60 years, and providing the associated data products to the public. LASP has a long history, in particular, of making space-based measurements of the solar irradiance, which serves as crucial input to several areas of scientific research, including solar-terrestrial interactions, atmospheric, and climate. LISIRD, the LASP Interactive Solar Irradiance Data Center, serves these datasets to the public, including solar spectral irradiance (SSI) and total solar irradiance (TSI) data. The LASP extended metadata repository, LEMR, is a database of information about the datasets served by LASP, such as parameters, uncertainties, temporal and spectral ranges, current version, alerts, etc. It serves as the definitive, single source of truth for that information. The database is populated with information garnered via web forms and automated processes. Dataset owners keep the information current and verified for datasets under their purview. This information can be pulled dynamically for many purposes. Web sites such as LISIRD can include this information in web page content as it is rendered, ensuring users get current, accurate information. It can also be pulled to create metadata records in various metadata formats, such as SPASE (for heliophysics) and ISO 19115. Once these records are be made available to the appropriate registries, our data will be discoverable by users coming in via those organizations. The database is implemented as a RDF triplestore, a collection of instances of subject-object-predicate data entities identifiable with a URI. This capability coupled with SPARQL over HTTP read access enables semantic queries over the repository contents. To create the repository we leveraged VIVO, an open source semantic web application, to manage and create new ontologies and populate repository content. A variety of ontologies were used in creating the triplestore, including ontologies that came with VIVO such as FOAF. Also, the W3C DCAT ontology was integrated and extended to describe properties of our data products that we needed to capture, such as spectral range. The presentation will describe the architecture, ontology issues, and tools used to create LEMR and plans for its evolution.
Nuclear localisation of LASP-1 correlates with poor long-term survival in female breast cancer.
Frietsch, J J; Grunewald, T G P; Jasper, S; Kammerer, U; Herterich, S; Kapp, M; Honig, A; Butt, E
2010-05-25
LIM and SH3 protein 1 (LASP-1) is a nucleo-cytoplasmatic signalling protein involved in cell proliferation and migration and is upregulated in breast cancer in vitro studies have shown that LASP-1 might be regulated by prostate-derived ETS factor (PDEF), p53 and/or LASP1 gene amplification. This current study analysed the prognostic significance of LASP-1 on overall survival (OS) in 177 breast cancer patients and addressed the suggested mechanisms of LASP-1-regulation. Nucleo-cytoplasmatic LASP-1-positivity of breast carcinoma samples was correlated with long-term survival, clinicopathological parameters, Ki67-positivity and PDEF expression. Rate of LASP1 amplification was determined in micro-dissected primary breast cancer cells using quantitative RT-PCR. Cell-phase dependency of nuclear LASP-1-localisation was studied in synchronised cells. In addition, LASP-1, PDEF and p53 expression was compared in cell lines of different tumour entities to define principles for LASP-1-regulation. We showed that LASP-1 overexpression is not due to LASP1 gene amplification. Moreover, no correlation between p53-mutations or PDEF-expression and LASP-1-status was observed. However, nuclear LASP-1-localisation in breast carcinomas is increased during proliferation with peak in G2/M-phase and correlated significantly with Ki67-positivity and poor OS. Our results provide evidence that nuclear LASP-1-positivity may serve as a negative prognostic indicator for long-term survival of breast cancer patients.
Dejima, Takashi; Imada, Kenjiro; Takeuchi, Ario; Shiota, Masaki; Leong, Jeffrey; Tombe, Tabitha; Tam, Kevin; Fazli, Ladan; Naito, Seiji; Gleave, Martin E; Ong, Christopher J
2017-02-01
LIM and SH3 domain protein 1 (LASP1) has been implicated in several human malignancies and has been shown to predict PSA recurrence in prostate cancer. However, the anti-tumor effect of LASP1 knockdown and the association between LASP1 and the androgen receptor (AR) remains unclear. The aim of this study is to clarify the significance of LASP1 as a target for prostate cancer, and to test the effect of silencing LASP1 in vivo using antisense oligonucleotides (ASO). A tissue microarray (TMA) was performed to characterize the differences in LASP1 expression in prostate cancer treated after hormone deprivation therapy. Flow cytometry was used to analyze cell cycle. We designed LASP1 ASO for knockdown of LASP1 in vivo studies. The expression of LASP1 in TMA was increased after androgen ablation and persisted in castration resistant prostate cancer (CRPC). Also in TMA, compared with LNCaP cell, LASP1 expression is elevated in CRPC cell lines (C4-2 and VehA cells). Interestingly, suppression of AR elevated LASP1 expression conversely, AR activation decreased LASP1 expression. Silencing of LASP1 reduced cell growth through G1 arrest which was accompanied by a decrease of cyclin D1. Forced overexpression of LASP1 promoted cell cycle and induced cell growth which was accompanied by an increase of cyclin D1. Systemic administration of LASP1 ASO with athymic mice significantly inhibited tumor growth in CRPC xenografts. These results indicate that LASP1 is negatively regulated by AR at the transcriptional level and promotes tumor growth through induction of cell cycle, ultimately suggesting that LASP1 may be a potential target in prostate cancer treatment. Prostate 77:309-320, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.
Krintel, Christian; Frydenvang, Karla; Ceravalls de Rabassa, Anna; Kaern, Anne M; Gajhede, Michael; Pickering, Darryl S; Kastrup, Jette S
2014-05-01
In purification of the ionotropic glutamate receptor A2 (GluA2) ligand-binding domain (LBD), L-Glu-supplemented buffers have previously been used for protein stabilization during the procedure. This sometimes hampers structural studies of low-affinity ligands, because L-Glu is difficult to displace, despite extensive dialysis. Here, we show that L-Asp binds to full-length GluA2 with low affinity (Ki = 0.63 mM) and to the GluA2 LBD with even lower affinity (Ki = 2.6 mM), and we use differential scanning fluorimetry to show that L-Asp is able to stabilize the isolated GluA2 LBD. We also show that L-Asp can replace L-Glu during purification, providing both equal yields and purity of the resulting protein sample. Furthermore, we solved three structures of the GluA2 LBD in the presence of 7.5, 50 and 250 mM L-Asp. Surprisingly, with 7.5 mM L-Asp, the GluA2 LBD crystallized as a mixed dimer, with L-Glu being present in one subunit, and neither L-Asp nor L-Glu being present in the other subunit. Thus, residual L-Glu is retained from the expression medium. On the other hand, only L-Asp was found at the binding site when 50 or 250 mM L-Asp was used for crystallization. The binding mode observed for L-Asp at the GluA2 LBD is very similar to that described for L-Glu. Taking our findings together, we have shown that L-Asp can be used instead of L-Glu for ligand-dependent stabilization of the GluA2 LBD during purification. This will enable structural studies of low-affinity ligands for lead optimization in structure-based drug design. Structural data are available in the Protein Data Bank under accession numbers 4O3B (7.5 mM L-Asp), 4O3C (50 mM L-Asp), and 4O3A (250 mM L-Asp). © 2014 FEBS.
Orth, Martin F.; Cazes, Alex; Butt, Elke; Grunewald, Thomas G. P.
2015-01-01
The gene encoding the LIM and SH3 domain protein (LASP1) was cloned two decades ago from a cDNA library of breast cancer metastases. As the first protein of a class comprising one N-terminal LIM and one C-terminal SH3 domain, LASP1 founded a new LIM-protein subfamily of the nebulin group. Since its discovery LASP1 proved to be an extremely versatile protein because of its exceptional structure allowing interaction with various binding partners, its ubiquitous expression in normal tissues, albeit with distinct expression patterns, and its ability to transmit signals from the cytoplasm into the nucleus. As a result, LASP1 plays key roles in cell structure, physiological processes, and cell signaling. Furthermore, LASP1 overexpression contributes to cancer aggressiveness hinting to a potential value of LASP1 as a cancer biomarker. In this review we summarize published data on structure, regulation, function, and expression pattern of LASP1, with a focus on its role in human cancer and as a biomarker protein. In addition, we provide a comprehensive transcriptome analysis of published microarrays (n=2,780) that illustrates the expression profile of LASP1 in normal tissues and its overexpression in a broad range of human cancer entities. PMID:25622104
Endres, Marcel; Kneitz, Susanne; Orth, Martin F; Perera, Ruwan K; Zernecke, Alma; Butt, Elke
2016-09-27
The process of tumor invasion requires degradation of extracellular matrix by proteolytic enzymes. Cancer cells form protrusive invadopodia, which produce and release matrix metalloproteinases (MMPs) to degrade the basement membrane thereby enabling metastasis. We investigated the effect of LASP1, a newly identified protein in invadopodia, on expression, secretion and activation of MMPs in invasive breast tumor cell lines.By analyzing microarray data of in-house generated control and LASP1-depleted MDA-MB-231 breast cancer cells, we observed downregulation of MMP1, -3 and -9 upon LASP1 depletion. This was confirmed by Western blot analysis. Conversely, rescue experiments restored in part MMP expression and secretion. The regulatory effect of LASP1 on MMP expression was also observed in BT-20 breast cancer cells as well as in prostate and bladder cancer cell lines.In line with bioinformatic FunRich analysis of our data, which mapped a high regulation of transcription factors by LASP1, public microarray data analysis detected a correlation between high LASP1 expression and enhanced c-Fos levels, a protein that is part of the transcription factor AP-1 and known to regulate MMP expression. Compatibly, in luciferase reporter assays, AP-1 showed a decreased transcriptional activity after LASP1 knockdown.Zymography assays and Western blot analysis revealed an additional promotion of MMP secretion into the extracellular matrix by LASP1, thus, most likely, altering the microenvironment during cancer progression.The newly identified role of LASP1 in regulating matrix degradation by affecting MMP transcription and secretion elucidated the migratory potential of LASP1 overexpressing aggressive tumor cells in earlier studies.
Zhang, Han; Chen, Xunsheng; Bollag, Wendy B.; Bollag, Roni J.; Sheehan, Daniel J.; Chew, Catherine S.
2009-01-01
Lasp1 is an actin-binding, signaling pathway-regulated phosphoprotein that is overexpressed in several cancers. siRNA knockdown in cell lines retards cell migration, suggesting the possibility that Lasp1 upregulation influences cancer metastasis. Herein, we utilized a recently developed gene knockout model to assess the role of Lasp1 in modulating nontransformed cell functions. Wound healing and tumor initiation progressed more rapidly in Lasp1−/− mice compared with Lasp1+/+ controls. Embryonic fibroblasts (MEFs) derived from Lasp1−/− mice also migrated more rapidly in vitro. These MEFs characteristically possessed increased focal adhesion numbers and displayed more rapid attachment compared with wild-type MEFs. Differential microarray analyses revealed alterations in message expression for proteins implicated in cell migration, adhesion, and cytoskeletal organization. Notably, the focal adhesion protein, lipoma preferred partner (LPP), a zyxin family member and putative Lasp1 binding protein, was increased about twofold. Because LPP gene disruption reduces cell migration, we hypothesize that LPP plays a role in enhancing the migratory capacity of Lasp1−/− MEFs, perhaps by modifying the subcellular localization of other motility-associated proteins. The striking contrast in the functional effects of loss of Lasp1 in innate cells compared with cell lines reveals distinct differences in mechanisms of motility and attachment in these models. PMID:19531578
Face-selective crystal growth behavior of L-aspartic acid in the presence of L-asparagine
NASA Astrophysics Data System (ADS)
Sato, Hiroyasu; Doki, Norihito; Yoshida, Saki; Yokota, Masaaki; Shimizu, Kenji
2016-02-01
The kinetic mechanism of L-asparagine (L-Asn) action on L-aspartic acid (L-Asp) crystal growth, namely the face-selective effect of L-Asn on the L-Asp crystal growth rate in each direction, was examined. In the a-axis direction, the effect of L-Asn on the L-Asp crystal growth rate was small. Enhancement and inhibition of L-Asp crystal growth, and interestingly the dissolution of the L-Asp crystal face, were observed in the b-axis direction, depending on the amount of L-Asn added. In the c-axis direction, the L-Asp crystal growth rate decreased with the increase in the amount of L-Asn added, and the experimental results were well fitted with a Langmuir adsorption isotherm. The study showed that there were crystal growth conditions where enhancement and inhibition, as well as inhibition and dissolution, coexisted in the presence of an additive with a structure similar to the growing crystal.
Senior Laboratory Animal Technician | Center for Cancer Research
PROGRAM DESCRIPTION The Laboratory Animal Sciences Program (LASP) provides exceptional quality animal care and technical support services for animal research performed at the National Cancer Institute at the Frederick National Laboratory for Cancer Research. LASP executes this mission by providing a broad spectrum of state-of-the-art technologies and services that are focused on the design, generation, characterization and application of genetically engineered and biological animal models of human disease, which are aimed at the development of targeted diagnostics and therapies. LASP contributes to advancing human health, developing new treatments, and improving existing treatments for cancer and other diseases while ensuring safe and humane treatment of animals. KEY ROLES/RESPONSIBILITIES The Senior Laboratory Animal Technician will be responsible for: Daily tasks associated with the care, breeding and treatment of research animals for experimental purposes Management of rodent breeding colonies consisting of multiple, genetically complex strains and associated record keeping and database management Colony management procedures including: tail clipping, animal identification, weaning Data entry consistent with complex colony management Collection of routine diagnostic samples Coordinating shipment of live animals and specimens Performing rodent experimental procedures including basic necropsy and blood collection Observation and recording of physical signs of animal health Knowledge of safe working practices using chemical carcinogen and biological hazards Work schedule may include weekend and holiday hours This position is in support of the Center for Cancer Research (CCR).
The New LASP Interactive Solar IRradiance Datacenter (LISIRD)
NASA Astrophysics Data System (ADS)
Baltzer, T.; Wilson, A.; Lindholm, D. M.; Snow, M. A.; Woodraska, D.; Pankratz, C. K.
2017-12-01
The New LASP Interactive Solar IRradiance Datacenter (LISIRD) The University of Colorado at Boulder's Laboratory for Atmospheric and Space Physics (LASP) has a long history of providing state of the art Solar instrumentation and datasets to the community. In 2005, LASP created a web interface called LISIRD which provided plotting of and access to a number of Solar Irradiance measured and modeled datasets, and it has been used extensively by members of the community both within and outside of LASP. In August of 2017, LASP is set to release a new version of LISIRD for use by anyone interested in viewing and downloading the datasets it serves. This talk will describe the new LISIRD with emphasis on features enabled by it to include: New and more functional plotting interfaces Better dataset browse and search capabilities More datasets Easier to add datasets from a wider array of resources Cleaner interface with better use of screen real estate Much easier to update metadata describing each dataset Much of this capability is leveraged off new infrastructure that will also be touched upon.
Chan, Wai Kin; Lorenzi, Philip L.; Anishkin, Andriy; Purwaha, Preeti; Rogers, David M.; Sukharev, Sergei; Rempe, Susan B.; Weinstein, John N.
2014-01-01
l-Asparaginase (l-ASP) is a key component of therapy for acute lymphoblastic leukemia. Its mechanism of action, however, is still poorly understood, in part because of its dual asparaginase and glutaminase activities. Here, we show that l-ASP’s glutaminase activity is not always required for the enzyme’s anticancer effect. We first used molecular dynamics simulations of the clinically standard Escherichia coli l-ASP to predict what mutated forms could be engineered to retain activity against asparagine but not glutamine. Dynamic mapping of enzyme substrate contacts identified Q59 as a promising mutagenesis target for that purpose. Saturation mutagenesis followed by enzymatic screening identified Q59L as a variant that retains asparaginase activity but shows undetectable glutaminase activity. Unlike wild-type l-ASP, Q59L is inactive against cancer cells that express measurable asparagine synthetase (ASNS). Q59L is potently active, however, against ASNS-negative cells. Those observations indicate that the glutaminase activity of l-ASP is necessary for anticancer activity against ASNS-positive cell types but not ASNS-negative cell types. Because the clinical toxicity of l-ASP is thought to stem from its glutaminase activity, these findings suggest the hypothesis that glutaminase-negative variants of l-ASP would provide larger therapeutic indices than wild-type l-ASP for ASNS-negative cancers. PMID:24659632
Lasp1 misexpression influences chondrocyte differentiation in the vertebral column.
Hermann-Kleiter, Natascha; Ghaffari-Tabrizi, Nassim; Blumer, Michael J F; Schwarzer, Christoph; Mazur, Magdalena A; Artner, Isabella
2009-01-01
The mouse mutant wavy tail Tg(Col1a1-lacZ)304ng was created through transgene insertion and exhibits defects of the vertebral column. Homozygous mutant animals have compressed tail vertebrae and wedge-shaped intervertebral discs, resulting in a meandering tail. Delayed closure of lumbar neural arches and lack of processus spinosi have been observed; these defects become most prominent during the transition from cartilage to bone. The spina bifida was resistant to folic acid treatment, while retinoic acid administration caused severe skeletal defects in the mutant, but none in wild type control animals. The transgene integrated at chromosome 11 band D, in an area of high gene density. The insertion site was located between the transcription start sites of the Rpl23 and Lasp1 genes. LASP1 (an actin binding protein involved in cell migration and survival) was found to be produced in resting and hypertrophic chondrocytes in the vertebrae. In mutant vertebrae, temporal and spatial misexpression of Lasp1 was observed, indicating that alterations in Lasp1 transcription are most likely responsible for the observed phenotype. These data reveal a yet unappreciated role of Lasp1 in chondrocyte differentiation during cartilage to bone transition.
NASA Technical Reports Server (NTRS)
Noren, C.; Kanik, I.; Ajello, J.; McCartney, P.; Makarov, O.; McClintock, W.; Drake, V.
2001-01-01
In this Letter, we report for the first time, the ratio of the O I (135.6 nm)/O I (130.4 nm) absolute emission cross sections from electron-impact dissociative excitation of O-2 at 100 eV using facilities located at the University of Colorado, Laboratory for Atmospheric and Space Physics (LASP).
Interoperable Solar Data and Metadata via LISIRD 3
NASA Astrophysics Data System (ADS)
Wilson, A.; Lindholm, D. M.; Pankratz, C. K.; Snow, M. A.; Woods, T. N.
2015-12-01
LISIRD 3 is a major upgrade of the LASP Interactive Solar Irradiance Data Center (LISIRD), which serves several dozen space based solar irradiance and related data products to the public. Through interactive plots, LISIRD 3 provides data browsing supported by data subsetting and aggregation. Incorporating a semantically enabled metadata repository, LISIRD 3 users see current, vetted, consistent information about the datasets offered. Users can now also search for datasets based on metadata fields such as dataset type and/or spectral or temporal range. This semantic database enables metadata browsing, so users can discover the relationships between datasets, instruments, spacecraft, mission and PI. The database also enables creation and publication of metadata records in a variety of formats, such as SPASE or ISO, making these datasets more discoverable. The database also enables the possibility of a public SPARQL endpoint, making the metadata browsable in an automated fashion. LISIRD 3's data access middleware, LaTiS, provides dynamic, on demand reformatting of data and timestamps, subsetting and aggregation, and other server side functionality via a RESTful OPeNDAP compliant API, enabling interoperability between LASP datasets and many common tools. LISIRD 3's templated front end design, coupled with the uniform data interface offered by LaTiS, allows easy integration of new datasets. Consequently the number and variety of datasets offered by LISIRD has grown to encompass several dozen, with many more to come. This poster will discuss design and implementation of LISIRD 3, including tools used, capabilities enabled, and issues encountered.
Andrade, Augusto F; Borges, Kleiton S; Silveira, Vanessa S
2014-01-01
Great improvements have been made in acute lymphoblastic leukemia (ALL) treatment in the past decades, especially due to the use of l-asparaginase (l-ASP). Despite the significant success rate, several side effects mainly caused by toxicity, asparaginase silent inactivation, and cellular resistance, encourage an open debate regarding the optimal dosage and formulation of l-ASP. Alternative sources of asparaginases have been constantly investigated in order to overcome hypersensitivity clinical toxicity. Additionally, genomic modulation as gene expression profiling, genetic polymorphisms, and epigenetic changes is also being investigated concerning their role in cellular resistance to l-ASP. Understanding the mechanisms that mediate the resistance to l-ASP treatment may bring new insights into ALL pathobiology and contribute to the development of more effective treatment strategies. In summary, this review presents an overview on l-ASP data and focuses on cellular mechanisms underlying resistance and alternative therapies for the use of asparaginase in childhood ALL treatment. PMID:25210485
SORCE 11 years after launch: What's new? What's next?
NASA Astrophysics Data System (ADS)
Cahalan, Robert; Kopp, Greg; Pilewskie, Peter; Richard, Erik; Woods, Tom
2014-05-01
We discuss recent changes in estimates of the Total Solar Irradiance (TSI) and the energy budget. We highlight the historic closing of the calibration gap between the suite of TSI instruments, due largely to comparisons made with a cryogenic Transfer Radiometer Facility (TRF) located at the University of Colorado, built by UCO/LASP with support from NASA and NIST. The resulting continuous record of TSI promises to be a milestone in improving understanding of the Sun's impact on Earth's climate. Climate models are sensitive not only to TSI, but also to variations in the Spectral Solar Irradiance (SSI), and the vertical profiles of temperature and ozone are especially sensitive to SSI variations. Variations in SSI need further study before they may be considered as firmly established as TSI variations, which themselves remain controversial, despite a strengthening consensus over the SORCE epoch. The TSIS SIM has recently undergone comprehensive end-to-end calibration in the LASP SSI Radiometry Facility (SRF) utilizing the NIST SIRCUS laser system covering 210 - 2400 nm for SSI, a facility not yet available when SORCE launched in 2003. With SORCE follow-on missions such as the Total and Spectral Solar Irradiance Sensor (TSIS), we anticipate narrowing uncertainties in SSI variability that will be important to improving our understanding of the climate responses to solar forcing. The long-term goal of improving the ability to monitor Earth's energy balance, and the energy imbalance that drives global warming, will need continued improvements in the measurement of both shortwave solar and longwave earth-emitted radiation.
Crepel, F.; Dhanjal, S. S.; Sears, T. A.
1982-01-01
1. The responses of Purkinje cells to short duration (pulse) ionophoretic applications of L-aspartate (L-asp), L-glutamate (L-glu), N-methyl DL-aspartate (NMDLA) and quisqualic acid in their dendritic fields were studied in vitro on sagittal slices of lobules IX and X of the adult rat cerebellum. 2. Pulse application of L-asp or L-glu evoked transient and dose-dependent increases in the firing rate of the simple spikes recorded extracellularly as single units. When the ionophoretic electrode was positioned in the dendritic field of the Purkinje cells, the lowest thresholds for L-glu and L-asp mediated excitations of the cells were as low as 25 and 35 pC respectively, with a latency for maximal responses as brief as 7 ms. 3. In intracellular recordings these excitatory responses consisted of depolarizations of up to 18 mV in amplitude and with depolarizing slopes up to 0·52 mV/ms. They were generally unaccompanied by changes in cell input resistance in contrast to the marked decrease which occurred in response to steady applications of large doses of L-asp and L-glu. 4. The spatial distribution of the excitatory sites confirmed that the dendritic sensitivity to L-glu was greater than that of the soma and showed that the same was true for L-asp. In 34% of cells the sensitivity for L-asp declined markedly in the upper region of the molecular layer, whereas it remained high for L-glu; no such differential sensitivity was detected in the remaining 66% of cells. 5. Inhibitory responses, antagonized by 10-5 M-bicuculline in the bath, were also induced in Purkinje cells by L-glu and L-asp when the ionophoretic electrode was withdrawn from the excitatory sites by as little as 8 μm and up to 40 μm upward or downward along the track of parallel fibres or positioned as far as 250 μm laterally. 6. Whenever it was applied in the molecular layer, the pulse application of NMDLA elicited no excitatory response in Purkinje cells recorded extra or intracellularly. However, slow depolarizations accompanied by a slight increase in cell input resistance were obtained with steady applications of 20-50 nA of the drug for 20-30 s. 7. In contrast, pulse application of quisqualic acid appeared to have the same type of fast excitatory effect on Purkinje cells as L-asp and L-glu, but its potency was greater and its action more prolonged. Furthermore, its steady application led to an abrupt and marked decrease in cell membrane resistance. 8. The excitatory effects of L-asp, L-glu and quisqualic acid were antagonized by L-glutamic acid diethyl ester more consistently than by D-α-aminoadipate, suggesting together with previous observations that L-asp and L-glu act on Purkinje cells via quisqualic acid rather than via NMDLA receptors. PMID:6754909
Northrup, Nicole C; Rassnick, Kenneth M; Snyder, Laura A; Stone, Michael S; Kristal, Orna; Cotter, Susan M; Moore, Antony S
2002-01-01
Vincristine (VCR) and L-asparaginase (L-ASP) are commonly used to treat canine lymphoma. As single agents, these drugs are not myelosuppressive. However, in combination, VCR and L-ASP cause severe neutropenia in some dogs. It has been recommended that L-ASP be administered 12-24 hours after VCR to minimize toxicity. The purpose of this retrospective study was to determine the prevalence of neutropenia after VCR/L-ASP induction therapy for canine lymphoma and to evaluate risk factors for myelosuppression, especially the interval between VCR and L-ASP administration. Medical records of 147 dogs were reviewed. L-ASP was given 0 (n = 50), 6 (n = 23), 18 (n = 20), or 24 (n = 54) hours after VCR. Forty percent of the dogs were neutropenic 7 days after VCR/L-ASP, and 18% had neutrophil counts of <1,000 cells/microL. The median neutrophil count was 3,712 cells/microL (range 0-30,968 cells/microL). No correlation was found between administration interval and day 7 neutrophil count (P = .84) or development of gastrointestinal signs, including vomiting (P = .80), diarrhea (P = .52), and decreased appetite (P = .30). No significant predictors of neutropenia were identified. Higher clinical stage and substage b were associated with decreased appetite after treatment (P = .04 and .01, respectively). Sixteen percent of the dogs were hospitalized. This study demonstrates that VCR/L-ASP induction for canine lymphoma may result in neutropenia but that separation of VCR and L-ASP administration may not be necessary to avoid toxicity.
Solar Irradiance Data Products at the LASP Interactive Solar IRradiance Datacenter (LISIRD)
NASA Astrophysics Data System (ADS)
Lindholm, D. M.; Ware DeWolfe, A.; Wilson, A.; Pankratz, C. K.; Snow, M. A.; Woods, T. N.
2011-12-01
The Laboratory for Atmospheric and Space Physics (LASP) has developed the LASP Interactive Solar IRradiance Datacenter (LISIRD, http://lasp.colorado.edu/lisird/) web site to provide access to a comprehensive set of solar irradiance measurements and related datasets. Current data holdings include products from NASA missions SORCE, UARS, SME, and TIMED-SEE. The data provided covers a wavelength range from soft X-ray (XUV) at 0.1 nm up to the near infrared (NIR) at 2400 nm, as well as Total Solar Irradiance (TSI). Other datasets include solar indices, spectral and flare models, solar images, and more. The LISIRD web site features updated plotting, browsing, and download capabilities enabled by dygraphs, JavaScript, and Ajax calls to the LASP Time Series Server (LaTiS). In addition to the web browser interface, most of the LISIRD datasets can be accessed via the LaTiS web service interface that supports the OPeNDAP standard. OPeNDAP clients and other programming APIs are available for making requests that subset, aggregate, or filter data on the server before it is transported to the user. This poster provides an overview of the LISIRD system, summarizes the datasets currently available, and provides details on how to access solar irradiance data products through LISIRD's interfaces.
Fontanarosa, Carolina; Pane, Francesca; Sepe, Nunzio; Pinto, Gabriella; Trifuoggi, Marco; Squillace, Marta; Errico, Francesco; Usiello, Alessandro; Pucci, Piero; Amoresano, Angela
2017-01-01
Several studies have suggested that free d-Asp has a crucial role in N-methyl d-Asp receptor-mediated neurotransmission playing very important functions in physiological and pathological processes. This paper describes the development of an analytical procedure for the direct and simultaneous determination of free d-Asp, l-Asp and N-methyl d-Asp in specimens of different mouse brain tissues using chiral LC-MS/MS in Multiple Reaction Monitoring scan mode. After comparing three procedures and different buffers and extraction solvents, a simple preparation procedure was selected the analytes of extraction. The method was validated by analyzing l-Asp, d-Asp and N-methyl d-Asp recovery at different spiked concentrations (50, 100 and 200 pg/μl) yielding satisfactory recoveries (75-110%), and good repeatability. Limits of detection (LOD) resulted to be 0.52 pg/μl for d-Asp, 0.46 pg/μl for l-Asp and 0.54 pg/μl for NMDA, respectively. Limits of quantification (LOQ) were 1.57 pg/μl for d-Asp, 1.41 pg/μl for l-Asp and 1.64 pg/μl for NMDA, respectively. Different concentration levels were used for constructing the calibration curves which showed good linearity. The validated method was then successfully applied to the simultaneous detection of d-Asp, l-Asp and NMDA in mouse brain tissues. The concurrent, sensitive, fast, and reproducible measurement of these metabolites in brain tissues will be useful to correlate the amount of free d-Asp with relevant neurological processes, making the LC-MS/MS MRM method well suited, not only for research work but also for clinical analyses.
L-asparaginase inhibits invasive and angiogenic activity and induces autophagy in ovarian cancer
Yu, Minshu; Henning, Ryan; Walker, Amanda; Kim, Geoffrey; Perroy, Alyssa; Alessandro, Riccardo; Virador, Victoria; Kohn, Elise C
2012-01-01
Recent work identified L-asparaginase (L-ASP) as a putative therapeutic target for ovarian cancer. We suggest that L-ASP, a dysregulator of glycosylation, would interrupt the local microenvironment, affecting the ovarian cancer cell—endothelial cell interaction and thus angiogenesis without cytotoxic effects. Ovarian cancer cell lines and human microvascular endothelial cells (HMVEC) were exposed to L-ASP at physiologically attainable concentrations and subjected to analyses of endothelial tube formation, invasion, adhesion and the assessment of sialylated proteins involved in matrix-associated and heterotypic cell adhesion. Marked reduction in HMVEC tube formation in vitro, HMVEC and ovarian cancer cell invasion, and heterotypic cell-cell and cell-matrix adhesion was observed (P < 0.05–0.0001). These effects were associated with reduced binding to ß1integrin, activation of FAK, and cell surface sialyl LewisX (sLex) expression. No reduction in HMVEC E-selectin expression was seen consistent with the unidirectional inhibitory actions observed. L-ASP concentrations were non-toxic to either ovarian cancer or HMVEC lines in the time frame of the assays. However, early changes of autophagy were observed in both cell types with induction of ATG12, beclin-1, and cleavage of LC-3, indicating cell injury did occur. These data and the known mechanism of action of L-ASP on glycosylation of nascent proteins suggest that L-ASP reduces of ovarian cancer dissemination and progression through modification of its microenvironment. The reduction of ovarian cancer cell surface sLex inhibits interaction with HMVEC and thus HMVEC differentiation into tubes, inhibits interaction with the local matrix reducing invasive behaviour, and causes cell injury initiating autophagy in tumour and vascular cells. PMID:22333033
Sorce Observations of Solar Cycles 23 and 24 - What's New? What's Next?
NASA Astrophysics Data System (ADS)
Cahalan, R. F.; Kopp, G.; Pilewskie, P.; Richard, E. C.; Woods, T. N.
2014-12-01
We discuss recent changes in estimates of the Total Solar Irradiance (TSI, formerly "solar constant") and the energy budget. This more accurate value of TSI implies a more accurate estimate of the Sun's luminosity, and lifetime. We highlight the historic closing of the calibration gap between the suite of TSI instruments, due largely to comparisons made with a cryogenic Transfer Radiometer Facility (TRF) located at the University of Colorado, built by UCO/LASP with support from NASA and NIST. The resulting continuous record of TSI promises to be a milestone in improving understanding of the Sun's impact on Earth's climate. Climate models are sensitive not only to TSI, but also to variations in the Spectral Solar Irradiance (SSI), and the vertical profiles of temperature and ozone are especially sensitive to SSI variations. Variations in SSI need further study before they may be considered as firmly established as TSI variations, which themselves remain controversial, despite a strengthening consensus over the SORCE epoch. The TSIS SIM has recently undergone comprehensive end-to-end calibration in the LASP SSI Radiometry Facility (SRF) utilizing the NIST SIRCUS laser system covering 210-2400 nm for SSI, a facility not yet available when SORCE launched in 2003. With SORCE follow-on missions such as the Total and Spectral Solar Irradiance Sensor (TSIS), we anticipate narrowing uncertainties in SSI variability that will be important to improving our understanding of the climate responses to solar forcing. The long-term goal of improving the ability to monitor Earth's energy balance, and the energy imbalance that drives global warming, will need continued improvements in the measurement of both shortwave solar and longwave earth-emitted radiation.
Laboratory Animal Technician | Center for Cancer Research
PROGRAM DESCRIPTION The Laboratory Animal Sciences Program (LASP) provides exceptional quality animal care and technical support services for animal research performed at the National Cancer Institute at the Frederick National Laboratory for Cancer Research. LASP executes this mission by providing a broad spectrum of state-of-the-art technologies and services that are focused
Senior Laboratory Animal Technician | Center for Cancer Research
PROGRAM DESCRIPTION The Laboratory Animal Sciences Program (LASP) provides exceptional quality animal care and technical support services for animal research performed at the National Cancer Institute at the Frederick National Laboratory for Cancer Research. LASP executes this mission by providing a broad spectrum of state-of-the-art technologies and services that are focused
The LASP Interactive Solar IRradiance Datacenter (LISIRD)
NASA Astrophysics Data System (ADS)
Pankratz, C. K.; Lindholm, D. M.; Snow, M.; Knapp, B.; Woodraska, D.; Templeman, B.; Woods, T. N.; Eparvier, F. G.; Fontenla, J.; Harder, J.; McClintock, W. E.
2007-12-01
The Laboratory for Atmospheric and Space Physics (LASP) has been making space-based measurements of solar irradiance for many decades, and thus has established an extensive catalog of past and ongoing space- based solar irradiance measurements. In order to maximize the accessibility and usability of solar irradiance data and information from multiple missions, LASP is developing the LASP Interactive Solar IRradiance Datacenter (LISIRD) to better serve the needs of researchers, educators, and the general public. This data center is providing interactive and direct access to a comprehensive set of solar spectral irradiance measurements from the soft X-ray (XUV) at 0.1 nm up to the near infrared (NIR) at 2400 nm, as well as state-of-the-art measurements of Total Solar Irradiance (TSI). LASP researchers are also responsible for an extensive set of solar irradiance models and historical solar irradiance reconstructions, which will also be accessible via this data center over time. LISIRD currently provides access to solar irradiance data sets from the SORCE, TIMED-SEE, UARS-SOLSTICE, and SME instruments, spanning 1981 to the present, as well as a Lyman Alpha composite that is available from 1947 to the present. LISIRD also provides data products of interest to the space weather community, whose needs demand high time cadence and near real-time data delivery. This poster provides an overview of the LISIRD system, summarizes the data sets currently available, describes future plans and capabilities, and provides details on how to access solar irradiance data through LISIRD's various interfaces.
Impact of Convection on Surface Fluxes Observed During LASP/DYNAMO 2011
2014-12-01
20 Figure 8. FFM maneuver used in the LASP/DYNAMO experiment (from Wang et al. 2013...Atmosphere Response Experiment DYNAMO Dynamics of Madden-Julian Oscillation EM electro-magnetic EO electro-optical FFM flight-level flux mapping FVS...level flux mapping ( FFM ) modules. Convection modules consisted of dropsonde cloud survey or radar convective element maneuver. Dropsonde modules
NASA Astrophysics Data System (ADS)
Ware Dewolfe, A.; Wilson, A.; Lindholm, D. M.; Pankratz, C. K.; Snow, M.; Woods, T. N.
2009-12-01
The Laboratory for Atmospheric and Space Physics (LASP) is enhancing the LASP Interactive Solar IRradiance Datacenter (LISIRD) to provide access to a comprehensive set of solar spectral irradiance measurements. LISIRD has recently been updated to serve many new datasets and models, including sunspot index, photometric sunspot index, Lyman-alpha, and magnesium-II core-to-wing ratio. A new user interface emphasizes web-based interactive visualizations, allowing users to explore and compare this data before downloading it for analysis. The data provided covers a wavelength range from soft X-ray (XUV) at 0.1 nm up to the near infrared (NIR) at 2400 nm, as well as wavelength-independent Total Solar Irradiance (TSI). Combined data from the SORCE, TIMED-SEE, UARS-SOLSTICE, and SME instruments provide almost continuous coverage from 1981 to the present, while Hydrogen Lyman-alpha (121.6 nm) measurements / models date from 1947 to the present. This poster provides an overview of the LISIRD system, summarizes the data sets currently available, describes future plans and capabilities, and provides details on how to access solar irradiance data through LISIRD interfaces at http://lasp.colorado.edu/lisird/.
Couturier, Marie-Anne; Huguet, Françoise; Chevallier, Patrice; Suarez, Felipe; Thomas, Xavier; Escoffre-Barbe, Martine; Cacheux, Victoria; Pignon, Jean-Michel; Bonmati, Caroline; Sanhes, Laurence; Bories, Pierre; Daguindau, Etienne; Dorvaux, Véronique; Reman, Oumedaly; Frayfer, Jamile; Orvain, Corentin; Lhéritier, Véronique; Ifrah, Norbert; Dombret, Hervé; Hunault-Berger, Mathilde; Tanguy-Schmidt, Aline
2015-11-01
Central nervous system (CNS) thrombotic events are a well-known complication of acute lymphoblastic leukemia (ALL) induction therapy, especially with treatments including l-asparaginase (l-ASP). Data on risk factors and clinical evolution is still lacking in adult patients. We report on the clinical evolution of 22 CNS venous thrombosis cases occurring in 708 adults treated for ALL or lymphoblastic lymphoma (LL) with the Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL)-induction protocol, which included eight L-ASP (6,000 IU/m(2) ) infusions. The prevalence of CNS thrombosis was 3.1%. CNS thrombosis occurred after a median of 18 days (range: 11-31) when patients had received a median of three l-ASP injections (range: 2-7). Patients with CNS thrombosis exhibited a median antithrombin (AT) nadir of 47.5% (range: 36-67%) at Day 17 (range: D3-D28), and 95% of them exhibited AT levels lower than 60%. There were no evident increase in hereditary thrombotic risk factors prevalence, and thrombosis occurred despite heparin prophylaxis which was performed in 90% of patients. Acquired AT deficiency was frequently detected in patients with l-ASP-based therapy, and patients with CNS thrombosis received AT prophylaxis (45%) less frequently than patients without CNS thrombosis (83%), P = 0.0002). CNS thrombosis was lethal in 5% of patients, while 20% had persistent sequelae. One patient received all planned l-ASP infusions without recurrence of CNS thrombotic whereas l-ASP injections were discontinued in 20 patients during the management of thrombosis without a significant impact on overall survival (P = 0.4). © 2015 Wiley Periodicals, Inc.
Ahmed, Sahar; Sprules, Tara; Kaur, Kamaljit
2014-07-01
Formation of stable secondary structures by oligomers that mimic natural peptides is a key asset for enhanced biological response. Here we show that oligomeric β(3)-hexapeptides synthesized from L-aspartic acid monomers (β(3)-peptides 1, 5a, and 6) or homologated β(3)-amino acids (β(3)-peptide 2), fold into similar stable 14-helical secondary structures in solution, except that the former form right-handed 14-helix and the later form left-handed 14-helix. β(3)-Peptides from L-Asp monomers contain an additional amide bond in the side chains that provides opportunities for more hydrogen bonding. However, based on the NMR solution structures, we found that β(3)-peptide from L-Asp monomers (1) and from homologated amino acids (2) form similar structures with no additional side-chain interactions. These results suggest that the β(3)-peptides derived from L-Asp are promising peptide-mimetics that can be readily synthesized using L-Asp monomers as well as the right-handed 14-helical conformation of these β(3)-peptides (such as 1 and 6) may prove beneficial in the design of mimics for right-handed α-helix of α-peptides. © 2014 Wiley Periodicals, Inc.
NASA Astrophysics Data System (ADS)
Li, Yin; Lukács, András; Bordács, Sándor; Móczár, János; Nyitrai, Miklós; Hebling, János
2018-02-01
Low-frequency modes of L-Asp and L-Asn were studied in the range from 0.1 to 3.0 THz using time-domain Terahertz spectroscopy and density functional theory calculation. The results show that PBE-D2 shows more success than BLYP-D2 in prediction of THz absorption spectra. To compare their low-frequency modes, we adopted ;vibrational character ID strips; proposed by Schmuttenmaer and coworkers [Journal of Physical Chemistry B, 117, 10444(2013)]. We found that the most intense THz absorption peaks of two compounds both involve severe distortion of their hydrogen bonding networks. Due to less rigid hydrogen bonding network in L-Asp, the side chain (carboxyl group) of L-Asp exhibits larger motions than that (carboxamide group) of L-Asn in low-frequency modes.
Xu, Yan; Wang, Jin; Yang, Nan; Bai, Ju; Zhang, Peng-Yu; Gu, Liu-Fang; Lei, Bo; Liu, Jie; Wang, Fang-Xia; Huang, Bing-Qiao; Zhang, Wang-Gang; He, Ai-Li; Cao, Xing-Mei; Chen, Yin-Xia; Ma, Xiao-Rong
2016-04-01
To explore the effectiveness and safety of combined chemotherapy with pegasparaginase (PEG-Asp) for treatment of patients with acute lymphoblastic leukemia (ALL) and T cell non-Hodgkin's lymphoma (T-NHL) patients. A total of 62 ALL or T-NHL patients were diagnosed and treated in our department and were enrolled in this study. Among them, 22 patients received the combined chemotherapy with PEG-Asp, while the other 40 patients received the standard chemotherapy with L-asparaginase (L-Asp) as the control. Therapeutic effectiveness, adverse effects, duration and expense of hospitalization, treatment-related mortality and survival were evaluated and compared in 2 different groups. In group of combined chemotherapy with PEG-Asp, the overall response rate was 90.91% (20 cases), among them CR rate and PR rate are 77.27% (17 cases) and 13.64% (3 cases), respectively. In the group of standard chemotherapy with L-Asp, the overall response rate was 87.5% (35 cases), among them CR rate and PR rate were 72.5% (29 cases) and 15% (6 cases), respectively. The difference neither between PEG-Asp and L-Asp chemotherapy groups nor between ALL and T-NHL subgroups was significant (P > 0.05). The 6-month and 12-month overall survival rates were not significantly different between the PEG-Asp and L-Asp chemotherapy groups, respectively (P > 0.05). The adverse effects were identified as degree 1-2 according to the WHO criteria of drug toxicity. Neither the adverse effects identified as degree 3-4 nor the treatment-related death were observed. Expect for allergy and hyperglycaemia, the difference of side-effect incidence between the two groups were not significant (P > 0.05). The treatment for all the patients in PEG-Asp chemotherapy group was completed, while the treatment with L-Asp was completed only in 29 cases. Moreover, both average duration and expense of hospitalization after the combined chemotherapy were less than the control. With higher response rate, lower drug toxicity and allergy incidence, the combined chemotherapy with PEG-Asp can replace the standard chemotherapy with L-Asp in the treatment of ALL and T-NHL. The optimization of the combined chemotheropeutic protocols for more cases and long-term survival rates need to further and deeply explorate.
2013-09-30
Figure 1 – Measurement systems installed on R/V Roger Revelle for DYNAMO /LASP. Inset map shows locations of land-based sounding stations...oceanographic moorings and the research vessels Mirai and Revelle during the intensive observation period of DYNAMO . The black line outlines the flight...under which each dominates. Transmission profile plus near-surface mixing measurements from LASP/ DYNAMO are being used to assess bounds on the
L-Asparaginase monotherapy for EBV-positive T/NK lymphoproliferative diseases: A pilot Study.
Jinta, Minako; Imadome, Ken-Ichi; Komatsu, Honami; Yoshimori, Mayumi; Kurata, Morito; Fujiwara, Shigeyoshi; Miura, Osamu; Arai, Ayako
2015-03-30
We investigated the effects of L-asparaginase (L-asp) on Epstein-Barr virus (EBV)-positive T/NK lymphoproliferative diseases (EBV-T/ NK-LPDs). Seven doses of L-asp (6,000 U/m2) were administered intravenously, with one dose administered on every alternate day. Five consecutive patients were enrolled. Three patients completed the treatment. The clinical symptoms resolved in 1 patient who started the administration 8 months after the onset, being the earliest among the 5 patients. Her EBV-DNA level in whole blood markedly decreased to 0.08 times of that before treatment, and the level in plasma became undetectable. In the other 2 patients whose administration was started 3 and 3.5 years after the onset, however, a remarkable improvement was not detected. Treatment was discontinued in 2 patients because of disease progression or idiopathic dystonia. The mRNA levels of asparagine synthetase in EBV-infected cells were examined. The level from the patient who responded to L-asp treatment was low, but it did not correlate with the effects in the other patients. Liver dysfunction (grades 2 and 3) was observed in 2 patients and neutropenia (grade 3) was noted in 1 patient. In conclusion, the effect of L-asp as monotherapy in EBV-T/NK-LPDs is limited, and early treatment initiation might be effective.
Aircraft Measurements for Understanding Air-Sea Coupling and Improving Coupled Model Predictions
2013-09-30
physical parameterizations of the coupled model in various large-scale forcing conditions. OBJECTIVES The NOAA WP-3D efforts of DYNAMO /LASP intend...various phases of the MJO; 3) to extend point measurements on island and ships to a broader area near the DYNAMO region; and 4) To obtain a suite of...upper ocean characteristics from a large number of AXBT/AXCTD data. In addition, as one of the unique measurement strategy of LASP/ DYNAMO WP-3D project
NASA Technical Reports Server (NTRS)
Pankratz, Chris; Beland, Stephane; Craft, James; Baltzer, Thomas; Wilson, Anne; Lindholm, Doug; Snow, Martin; Woods, Thomas; Woodraska, Don
2018-01-01
The Laboratory for Atmospheric and Space Physics (LASP) at the University of Colorado in Boulder, USA operates the Solar Radiation and Climate Experiment (SORCE) NASA mission, as well as several other NASA spacecraft and instruments. Dozens of Solar Irradiance data sets are produced, managed, and disseminated to the science community. Data are made freely available to the scientific immediately after they are produced using a variety of data access interfaces, including the LASP Interactive Solar Irradiance Datacenter (LISIRD), which provides centralized access to a variety of solar irradiance data sets using both interactive and scriptable/programmatic methods. This poster highlights the key technological elements used for the NASA SORCE mission ground system to produce, manage, and disseminate data to the scientific community and facilitate long-term data stewardship. The poster presentation will convey designs, technological elements, practices and procedures, and software management processes used for SORCE and their relationship to data quality and data management standards, interoperability, NASA data policy, and community expectations.
2002-12-18
KENNEDY SPACE CENTER, FLA. -- A Pegasus XL Expendable Launch Vehicle is prepared for towing to the Multi-Purpose Payload Facility (MPPF) where it will undergo testing, verification, and three flight simulations prior to its scheduled launch. The vehicle, nestled beneath an Orbital Sciences L-1011 aircraft, arrived at the Cape Canaveral Air Force Station Skid Strip on Dec. 17. It is commissioned to carry NASA's Solar Radiation and Climate Experiment (SORCE) spacecraft into orbit in late January 2003. Built by Orbital Sciences Space Systems Group, SORCE will study and measure solar irradiance as a source of energy in the Earth's atmosphere with instruments built by the University of Colorado's Laboratory for Atmospheric and Space Physics (LASP).
2002-12-18
KENNEDY SPACE CENTER, FLA. -- A Pegasus XL Expendable Launch Vehicle sits atop a transporter following its arrival in the Multi-Purpose Payload Facility (MPPF) where it will undergo testing, verification, and three flight simulations prior to its scheduled launch. The vehicle, nestled beneath an Orbital Sciences L-1011 aircraft, arrived at the Cape Canaveral Air Force Station Skid Strip on Dec. 17. It is commissioned to carry NASA's Solar Radiation and Climate Experiment (SORCE) spacecraft into orbit in late January 2003. Built by Orbital Sciences Space Systems Group, SORCE will study and measure solar irradiance as a source of energy in the Earth's atmosphere with instruments built by the University of Colorado's Laboratory for Atmospheric and Space Physics (LASP).
2002-12-18
KENNEDY SPACE CENTER, FLA. -- A Pegasus XL Expendable Launch Vehicle is prepared for towing to the Multi-Purpose Payload Facility (MPPF) where it will undergo testing, verification, and three flight simulations prior to its scheduled launch. The vehicle, nestled beneath an Orbital Sciences L-1011 aircraft, arrived at the Cape Canaveral Air Force Station Skid Strip on Dec. 17. It is commissioned to carry NASA's Solar Radiation and Climate Experiment (SORCE) spacecraft into orbit in late January 2003. Built by Orbital Sciences Space Systems Group, SORCE will study and measure solar irradiance as a source of energy in the Earth's atmosphere with instruments built by the University of Colorado's Laboratory for Atmospheric and Space Physics (LASP).
Lauroyl-L-aspartate decreased food intake and body temperature in neonatal chicks.
Erwan, E; Chowdhury, V S; Ito, K; Furuse, M
2013-11-15
We hypothesized that the effects of L- and D-amino acids might be influenced when conjugated with fatty acid. Thus, the effects of oral administration of lauroyl-L-aspartate (Lau-L-Asp) as well as lauroyl-D-aspartate (Lau-D-Asp) were examined. In Experiment 1, oral administration of both Lau-L-Asp and Lau-D-Asp decreased food intake while L- or D-Asp did not influence food intake. Interestingly, only Lau-L-Asp decreased body temperature. Experiment 2 was conducted to determine whether non-conjugated mixture of L-Asp plus lauric acid has same effects under ad libitum feeding conditions. Lau-L-Asp decreased food intake and body temperature, but L-Asp plus lauric acid did not show any effect studied. In Experiment 3, we found that Lau-L-Asp declined food intake as well as time-dependently suppressed the body temperature in fasted chicks. However, L-Asp plus lauric acid did not show any effect. These results suggest that Lau-L-Asp may exert anorexigenic and hypothermic actions in chicks. © 2013.
2002-12-18
KENNEDY SPACE CENTER, FLA. -- Workers in clean room attire supervise the delivery of a Pegasus XL Expendable Launch Vehicle to the Multi-Purpose Payload Facility (MPPF). Next, it will be moved into a highbay where it will undergo testing, verification, and three flight simulations prior to its scheduled launch. The vehicle, nestled beneath an Orbital Sciences L-1011 aircraft, arrived at the Cape Canaveral Air Force Station Skid Strip on Dec. 17. It is commissioned to carry NASA's Solar Radiation and Climate Experiment (SORCE) spacecraft into orbit in late January 2003. Built by Orbital Sciences Space Systems Group, SORCE will study and measure solar irradiance as a source of energy in the Earth's atmosphere with four instruments built by the University of Colorado's Laboratory for Atmospheric and Space Physics (LASP).
2002-12-18
KENNEDY SPACE CENTER, FLA. -- A Pegasus XL Expendable Launch Vehicle sits atop a transporter following its arrival in the Multi-Purpose Payload Facility (MPPF). Next, it will be moved into a highbay where it will undergo testing, verification, and three flight simulations prior to its scheduled launch. The vehicle, nestled beneath an Orbital Sciences L-1011 aircraft, arrived at the Cape Canaveral Air Force Station Skid Strip on Dec. 17. It is commissioned to carry NASA's Solar Radiation and Climate Experiment (SORCE) spacecraft into orbit in late January 2003. Built by Orbital Sciences Space Systems Group, SORCE will study and measure solar irradiance as a source of energy in the Earth's atmosphere with instruments built by the University of Colorado's Laboratory for Atmospheric and Space Physics (LASP).
2002-12-18
KENNEDY SPACE CENTER, FLA. -- A Pegasus XL Expendable Launch Vehicle sits atop a transporter following its arrival in the Multi-Purpose Payload Facility (MPPF). Next, it will be moved into a highbay where it will undergo testing, verification, and three flight simulations prior to its scheduled launch. The vehicle, nestled beneath an Orbital Sciences L-1011 aircraft, arrived at the Cape Canaveral Air Force Station Skid Strip on Dec. 17. It is commissioned to carry NASA's Solar Radiation and Climate Experiment (SORCE) spacecraft into orbit in late January 2003. Built by Orbital Sciences Space Systems Group, SORCE will study and measure solar irradiance as a source of energy in the Earth's atmosphere with instruments built by the University of Colorado's Laboratory for Atmospheric and Space Physics (LASP).
Regulation of Cell Wall Plasticity by Nucleotide Metabolism in Lactococcus lactis*
Solopova, Ana; Formosa-Dague, Cécile; Courtin, Pascal; Furlan, Sylviane; Veiga, Patrick; Péchoux, Christine; Armalyte, Julija; Sadauskas, Mikas; Kok, Jan; Hols, Pascal; Dufrêne, Yves F.; Kuipers, Oscar P.; Chapot-Chartier, Marie-Pierre; Kulakauskas, Saulius
2016-01-01
To ensure optimal cell growth and separation and to adapt to environmental parameters, bacteria have to maintain a balance between cell wall (CW) rigidity and flexibility. This can be achieved by a concerted action of peptidoglycan (PG) hydrolases and PG-synthesizing/modifying enzymes. In a search for new regulatory mechanisms responsible for the maintenance of this equilibrium in Lactococcus lactis, we isolated mutants that are resistant to the PG hydrolase lysozyme. We found that 14% of the causative mutations were mapped in the guaA gene, the product of which is involved in purine metabolism. Genetic and transcriptional analyses combined with PG structure determination of the guaA mutant enabled us to reveal the pivotal role of the pyrB gene in the regulation of CW rigidity. Our results indicate that conversion of l-aspartate (l-Asp) to N-carbamoyl-l-aspartate by PyrB may reduce the amount of l-Asp available for PG synthesis and thus cause the appearance of Asp/Asn-less stem peptides in PG. Such stem peptides do not form PG cross-bridges, resulting in a decrease in PG cross-linking and, consequently, reduced PG thickness and rigidity. We hypothesize that the concurrent utilization of l-Asp for pyrimidine and PG synthesis may be part of the regulatory scheme, ensuring CW flexibility during exponential growth and rigidity in stationary phase. The fact that l-Asp availability is dependent on nucleotide metabolism, which is tightly regulated in accordance with the growth rate, provides L. lactis cells the means to ensure optimal CW plasticity without the need to control the expression of PG synthesis genes. PMID:27022026
Racemization at the Asp 58 residue in αA-crystallin from the lens of high myopic cataract patients.
Zhu, Xiang-Jia; Zhang, Ke-Ke; He, Wen-Wen; Du, Yu; Hooi, Michelle; Lu, Yi
2018-02-01
Post-translational modifications in lens proteins are key causal factors in cataract. As the most abundant post-translational modification in the lens, racemization may be closely related to the pathogenesis of cataract. Racemization of αA-crystallin, a crucial structural and heat shock protein in the human lens, could significantly influence its structure and function. In previous studies, elevated racemization from l-Asp 58 to d-isoAsp58 in αA-crystallin has been found in age-related cataract (ARC) lenses compared to normal aged human lenses. However, the role of racemization in high myopic cataract (HMC), which is characterized by an early onset of nuclear cataract, remains unknown. In the current study, apparently different from ARC, significantly increased racemization from l-Asp 58 to d-Asp 58 in αA-crystallin was identified in HMC lenses. The average racemization rates for each Asp isoform were calculated in ARC and HMC group. In ARC patients, the conversion of l-Asp 58 to d-isoAsp 58, up to 31.89%, accounted for the main proportion in racemization, which was in accordance with the previous studies. However, in HMC lenses, the conversion of l-Asp 58 to d-Asp 58, as high as 35.44%, accounted for the largest proportion of racemization in αA-crystallin. The different trend in the conversion of αA-crystallin by racemization, especially the elevated level of d-Asp 58 in HMC lenses, might prompt early cataractogenesis and a possible explanation of distinct phenotypes of cataract in HMC. © 2017 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine.
NASA Astrophysics Data System (ADS)
Nelson, G.; Cobabe-Ammann, E.
2004-12-01
Colorado MESA is an after school program operating throughout the state with a long track record in promoting science, math and engineering education to largely underserved K-12 student populations. Currently, 81 percent of MESA students are from groups underrepresented in the math/science careers, and 85 percent of MESA students come from low- and moderate-income families. Through a combination of weekly student programs, field trips to universities and industry partners, family orientations, individual academic counseling and required curriculum, Colorado MESA offers an opportunity for students to explore STEM subjects and careers that they might not otherwise have access to - with tangible results. In the Colorado MESA Class of 2003, 97 percent of students planned on entering college this fall, with 86 percent indicating that they will enroll in math/science-based majors. In the last year, the University of Colorado's Laboratory for Atmospheric and Space Physics, a large space and earth sciences institute, has relied on the Colorado MESA program as its primary K-12 partner in Education and Public Outreach. LASP incorporates MESA into its proposal writing opportunities, from E/PO additions to individual research proposals to mission-level educational programs. In addition to funding opportunities, LASP provides scientists and engineers in a variety of contexts and content areas, while MESA works to incorporate those resources into their after school programs. The interface between the after school programs and the research institution requires ongoing communication and coordination in order to evaluate and fine-tune curriculum and activities based on feedback from MESA advisors and teachers. Currently, the MESA/LASP partnership has funded programs in astrobiology, planetary sciences and engineering.
Solar Irradiance Data Products at the LASP Interactive Solar IRradiance Datacenter (LISIRD)
NASA Astrophysics Data System (ADS)
Ware Dewolfe, A.; Wilson, A.; Lindholm, D. M.; Pankratz, C. K.; Snow, M. A.; Woods, T. N.
2010-12-01
The Laboratory for Atmospheric and Space Physics (LASP) has developed the LASP Interactive Solar IRradiance Datacenter (LISIRD) to provide access to a comprehensive set of solar irradiance measurements. LISIRD has recently been updated to serve many new datasets and models, including data from SORCE, UARS-SOLSTICE, SME, and TIMED-SEE, and model data from the Flare Irradiance Spectral Model (FISM). The user interface emphasizes web-based interactive visualizations, allowing users to explore and compare this data before downloading it for analysis. The data provided covers a wavelength range from soft X-ray (XUV) at 0.1 nm up to the near infrared (NIR) at 2400 nm, as well as wavelength-independent Total Solar Irradiance (TSI). Combined data from the SORCE, TIMED-SEE, UARS-SOLSTICE, and SME instruments provide continuous coverage from 1981 to the present, while Lyman-alpha measurements, FISM daily data, and TSI models date from the 1940s to the present. LISIRD will also host Glory TSI data as part of the SORCE data system. This poster provides an overview of the LISIRD system, summarizes the data sets currently available, describes future plans and capabilities, and provides details on how to access solar irradiance data through LISIRD’s interfaces.
2002-12-18
KENNEDY SPACE CENTER, FLA. -- A Pegasus XL Expendable Launch Vehicle is seen moments after being detached from the underside of an Orbital Sciences L-1011 aircraft and lowered onto a transporter. The aircraft, with the launch vehicle nestled beneath, arrived at the Cape Canaveral Air Force Station Skid Strip on Dec. 17. Next, the vehicle will be towed to the Multi-Purpose Payload Facility (MPPF) where it will undergo testing, verification, and three flight simulations prior to its scheduled launch in late January 2003. It will carry NASA's Solar Radiation and Climate Experiment (SORCE) spacecraft into orbit. Built by Orbital Sciences Space Systems Group, SORCE will study and measure solar irradiance as a source of energy in the Earth's atmosphere with instruments built by the University of Colorado's Laboratory for Atmospheric and Space Physics (LASP).
TIMED solar EUV experiment: preflight calibration results for the XUV photometer system
NASA Astrophysics Data System (ADS)
Woods, Thomas N.; Rodgers, Erica M.; Bailey, Scott M.; Eparvier, Francis G.; Ucker, Gregory J.
1999-10-01
The Solar EUV Experiment (SEE) on the NASA Thermosphere, Ionosphere, and Mesosphere Energetics and Dynamics (TIMED) mission will measure the solar vacuum ultraviolet (VUV) spectral irradiance from 0.1 to 200 nm. To cover this wide spectral range two different types of instruments are used: a grating spectrograph for spectra between 25 and 200 nm with a spectral resolution of 0.4 nm and a set of silicon soft x-ray (XUV) photodiodes with thin film filters as broadband photometers between 0.1 and 35 nm with individual bandpasses of about 5 nm. The grating spectrograph is called the EUV Grating Spectrograph (EGS), and it consists of a normal- incidence, concave diffraction grating used in a Rowland spectrograph configuration with a 64 X 1024 array CODACON detector. The primary calibrations for the EGS are done using the National Institute for Standards and Technology (NIST) Synchrotron Ultraviolet Radiation Facility (SURF-III) in Gaithersburg, Maryland. In addition, detector sensitivity and image quality, the grating scattered light, the grating higher order contributions, and the sun sensor field of view are characterized in the LASP calibration laboratory. The XUV photodiodes are called the XUV Photometer System (XPS), and the XPS includes 12 photodiodes with thin film filters deposited directly on the silicon photodiodes' top surface. The sensitivities of the XUV photodiodes are calibrated at both the NIST SURF-III and the Physikalisch-Technische Bundesanstalt (PTB) electron storage ring called BESSY. The other XPS calibrations, namely the electronics linearity and field of view maps, are performed in the LASP calibration laboratory. The XPS and solar sensor pre-flight calibration results are primarily discussed as the EGS calibrations at SURF-III have not yet been performed.
ACRIM3 and the Total Solar Irradiance database
NASA Astrophysics Data System (ADS)
Willson, Richard C.
2014-08-01
The effects of scattering and diffraction on the observations of the ACRIMSAT/ACRIM3 satellite TSI monitoring mission have been characterized by the preflight calibration approach for satellite total solar irradiance (TSI) sensors implemented at the LASP/TRF (Laboratory for Atmospheric and Space Physics/Total Solar Irradiance Radiometer Facility). The TRF also calibrates the SI (International System of units) traceability to the NIST (National Institute of Standards and Technology) cryo-radiometric scale. ACRIM3's self-calibration agrees with NIST to within the uncertainty of the test procedure (˜500 ppm). A correction of ˜5000 ppm was found for scattering and diffraction that has significantly reduced the scale difference between the results of the ACRIMSAT/ACRIM3 and SORCE/TIM satellite experiments. Algorithm updates reflecting more than 10 years of mission experience have been made that further improve the ACRIM3 results by eliminating some thermally driven signal and increasing the signal to noise ratio. The result of these changes is a more precise and detailed picture of TSI variability. Comparison of the results from the ACRIM3, SORCE/TIM and SOHO/VIRGO satellite experiments demonstrate the near identical detection of TSI variability on all sub-annual temporal and amplitude scales during the TIM mission. The largest occurs at the rotational period of the primary solar activity longitudes. On the decadal timescale, while ACRIM3 and VIRGO results exhibit close agreement throughout, TIM exhibits a consistent 500 ppm upward trend relative to ACRIM3 and VIRGO. A solar magnetic activity area proxy for TSI has been used to demonstrate that the ACRIM TSI composite and its +0.037 %/decade TSI trend during solar cycles 21-23 is the most likely correct representation of the extant satellite TSI database. The occurrence of this trend during the last decades of the 20th century supports a more robust contribution of TSI variation to detected global temperature increase during this period than predicted by current climate models.
2002-10-26
KENNEDY SPACE CENTER, FLA. -- A container with the Solar Radiation and Climate Experiment (SORCE) spacecraft inside is offloaded at the Multi-Purpose Processing Facility at KSC. The spacecraft will undergo final processing for launch. SORCE is equipped with four instruments that will measure variations in solar radiation much more accurately than anything now in use and observe some of the spectral properties of solar radiation for the first time. With data from NASA's SORCE mission, researchers should be able to follow how the Sun affects our climate now and in the future. The SORCE project is managed by NASA's Goddard Space Flight Center. The instruments on the SORCE spacecraft are built by the Laboratory for Atmospheric and Space Physics (LASP). Launch of SORCE aboard a Pegasus XL rocket is scheduled for mid-December 2002. Launch site is Cape Canaveral Air Force Station, Fla.
2002-10-28
KENNEDY SPACE CENTER, FLA. - In the Multi-Purpose Processing Facility at KSC, workers unpack the Solar Radiation and Climate Experiment (SORCE) spacecraft. SORCE arrived at Kennedy Space Center Oct. 26 to begin final processing. SORCE is equipped with four instruments that will measure variations in solar radiation much more accurately than anything now in use and observe some of the spectral properties of solar radiation for the first time. With data from NASA's SORCE mission, researchers should be able to follow how the Sun affects our climate now and in the future. The SORCE project is managed by NASA's Goddard Space Flight Center. The instruments on the SORCE spacecraft are built by the Laboratory for Atmospheric and Space Physics (LASP). Launch of SORCE aboard a Pegasus XL rocket is scheduled for mid-December 2002. Launch site is Cape Canaveral Air Force Station, Fla.
2002-10-28
KENNEDY SPACE CENTER, FLA. -- Workers in the Multi-Purpose Processing Facility at KSC help guide the Solar Radiation and Climate Experiment (SORCE) spacecraft onto a workstand. SORCE arrived at Kennedy Space Center Oct. 26 to begin final processing. SORCE is equipped with four instruments that will measure variations in solar radiation much more accurately than anything now in use and observe some of the spectral properties of solar radiation for the first time. With data from NASA's SORCE mission, researchers should be able to follow how the Sun affects our climate now and in the future. The SORCE project is managed by NASA's Goddard Space Flight Center. The instruments on the SORCE spacecraft are built by the Laboratory for Atmospheric and Space Physics (LASP). Launch of SORCE aboard a Pegasus XL rocket is scheduled for mid-December 2002. Launch site is Cape Canaveral Air Force Station, Fla.
2002-10-28
KENNEDY SPACE CENTER, FLA. - Workers in the Multi-Purpose Processing Facility at KSC look over the Solar Radiation and Climate Experiment (SORCE) spacecraft. SORCE arrived at Kennedy Space Center Oct. 26 to begin final processing. SORCE is equipped with four instruments that will measure variations in solar radiation much more accurately than anything now in use and observe some of the spectral properties of solar radiation for the first time. With data from NASA's SORCE mission, researchers should be able to follow how the Sun affects our climate now and in the future. The SORCE project is managed by NASA's Goddard Space Flight Center. The instruments on the SORCE spacecraft are built by the Laboratory for Atmospheric and Space Physics (LASP). Launch of SORCE aboard a Pegasus XL rocket is scheduled for mid-December 2002. Launch site is Cape Canaveral Air Force Station, Fla.
2002-10-28
KENNEDY SPACE CENTER, FLA. -- Workers in the Multi-Purpose Processing Facility at KSC lift the Solar Radiation and Climate Experiment (SORCE) spacecraft to move it to a workstand. SORCE arrived at Kennedy Space Center Oct. 26 to begin final processing. SORCE is equipped with four instruments that will measure variations in solar radiation much more accurately than anything now in use and observe some of the spectral properties of solar radiation for the first time. With data from NASA's SORCE mission, researchers should be able to follow how the Sun affects our climate now and in the future. The SORCE project is managed by NASA's Goddard Space Flight Center. The instruments on the SORCE spacecraft are built by the Laboratory for Atmospheric and Space Physics (LASP). Launch of SORCE aboard a Pegasus XL rocket is scheduled for mid-December 2002. Launch site is Cape Canaveral Air Force Station, Fla.
2002-10-28
KENNEDY SPACE CENTER, FLA. -- In the Multi-Purpose Processing Facility at KSC, the Solar Radiation and Climate Experiment (SORCE) spacecraft rests in a horizontal position on a workstand after rotation and removal of its outer covering. SORCE arrived at Kennedy Space Center Oct. 26 to begin final processing. SORCE is equipped with four instruments that will measure variations in solar radiation much more accurately than anything now in use and observe some of the spectral properties of solar radiation for the first time. With data from NASA's SORCE mission, researchers should be able to follow how the Sun affects our climate now and in the future. The SORCE project is managed by NASA's Goddard Space Flight Center. The instruments on the SORCE spacecraft are built by the Laboratory for Atmospheric and Space Physics (LASP). Launch of SORCE aboard a Pegasus XL rocket is scheduled for mid-December 2002. Launch site is Cape Canaveral Air Force Station, Fla.
Lautscham, E M; Kessler, M; Ernst, T; Willimzig, L; Neiger, R
2017-03-25
The recommendation to treat canine lymphoma with a discontinuous protocol is based on small case numbers and mostly historic controls. This study compares duration of first remission (DFR) and overall survival time (ST) with a discontinuous protocol to the same protocol with maintenance phase. 408 dogs were treated with a CHOP-LAsp (C=cyclophosphamide; H=hydroxydaunorubicin; O=Oncovin; P=prednisolone; LAsp=l-asparaginase)-based 28-week induction protocol. In 75 dogs (cohort 1), this was followed by a maintenance phase consisting of vincristine, chlorambucil and actinomycin-D with a total treatment duration of two years. In the subsequent 333 dogs, therapy was discontinued after induction (cohort 2). Median DFR and ST in cohort 1 were 216 and 375 days and 184 and 304 days in cohort 2. 6-Month, 1-year and 2-year survival rates in cohort 1 were 73 per cent, 50 per cent, 24 per cent and 67 per cent, 39 per cent, 21 per cent in cohort 2. There was no significant difference between the two protocols (P=0.291 for ST, P=0.071 for DFR). On multivariate analysis, corticosteroid pretreatment (P=0.005), thrombocytopenia at diagnosis (P=0.019), stage (P=0.009), substage b at relapse (P<0.001), age (P=0.002) and incomplete or unstable remission necessitating intensification of therapy (P=0.004) were negatively correlated with ST in both groups. This study supports the use of a discontinuous protocol for canine multicentric lymphoma. British Veterinary Association.
NASA Astrophysics Data System (ADS)
Lindholm, D. M.; Wilson, A.
2010-12-01
The Laboratory for Atmospheric and Space Physics at the University of Colorado has developed an Open Source, OPeNDAP compliant, Java Servlet based, RESTful web service to serve time series data. In addition to handling OPeNDAP style requests and returning standard responses, existing modules for alternate output formats can be reused or customized. It is also simple to reuse or customize modules to directly read various native data sources and even to perform some processing on the server. The server is built around a common data model based on the Unidata Common Data Model (CDM) which merges the NetCDF, HDF, and OPeNDAP data models. The server framework features a modular architecture that supports pluggable Readers, Writers, and Filters via the common interface to the data, enabling a workflow that reads data from their native form, performs some processing on the server, and presents the results to the client in its preferred form. The service is currently being used operationally to serve time series data for the LASP Interactive Solar Irradiance Data Center (LISIRD, http://lasp.colorado.edu/lisird/) and as part of the Time Series Data Server (TSDS, http://tsds.net/). I will present the data model and how it enables reading, writing, and processing concerns to be separated into loosely coupled components. I will also share thoughts for evolving beyond the time series abstraction and providing a general purpose data service that can be orchestrated into larger workflows.
Erwan, Edi; Chowdhury, Vishwajit Sur; Nagasawa, Mao; Goda, Ryosei; Otsuka, Tsuyoshi; Yasuo, Shinobu; Furuse, Mitsuhiro
2014-07-25
L-Aspartate (L-Asp) and D-aspartate (D-Asp) are physiologically important amino acids in mammals and birds. However, the functions of these amino acids have not yet been fully understood. In this study, we therefore examined the effects of L-Asp and D-Asp in terms of regulating body temperature, plasma metabolites and catecholamines in chicks. Chicks were first orally administered with different doses (0, 3.75, 7.5 and 15 mmol/kg body weight) of L- or D-Asp to monitor the effects of these amino acids on rectal temperature during 120 min of the experimental period. Oral administration of D-Asp, but not of L-Asp, linearly decreased the rectal temperature in chicks. Importantly, orally administered D-Asp led to a significant reduction in body temperature in chicks even under high ambient temperature (HT) conditions. However, centrally administered D-Asp did not significantly influence the body temperature in chicks. As for plasma metabolites and catecholamines, orally administered D-Asp led to decreased triacylglycerol and uric acid concentrations and increased glucose and chlorine concentrations but did not alter plasma catecholamines. These results suggest that oral administration of D-Asp may play a potent role in reducing body temperature under both normal and HT conditions. The alteration of plasma metabolites further indicates that D-Asp may contribute to the regulation of metabolic activity in chicks. Copyright © 2014 Elsevier Inc. All rights reserved.
Terbium-Aspartic Acid Nanocrystals with Chirality-Dependent Tunable Fluorescent Properties.
Ma, Baojin; Wu, Yu; Zhang, Shan; Wang, Shicai; Qiu, Jichuan; Zhao, Lili; Guo, Daidong; Duan, Jiazhi; Sang, Yuanhua; Li, Linlin; Jiang, Huaidong; Liu, Hong
2017-02-28
Terbium-aspartic acid (Tb-Asp) nanocrystals with chirality-dependent tunable fluorescent properties can be synthesized through a facile synthesis method through the coordination between Tb and Asp. Asp with different chirality (dextrorotation/d and levogyration/l) changes the stability of the coordination center following fluorescent absorption/emission ability differences. Compared with l-Asp, d-Asp can coordinate Tb to form a more stable center, following the higher quantum yield and longer fluorescence life. Fluorescence intensity of Tb-Asp linearly increases with increase ratio of d-Asp in the mixed chirality Tb-Asp system, and the fluorescent properties of Tb-Asp nanocrystals can be tuned by adjusting the chirality ratio. Tb-Asp nanocrystals possess many advantage, such as high biocompatibility, without any color in visible light irradiation, monodispersion with very small size, and long fluorescent life. Those characteristics will give them great potential in many application fields, such as low-cost antifake markers and advertisements using inkjet printers or for molds when dispersed in polydimethylsiloxane. In addition, europium can also be used to synthesize Eu-Asp nanoparticles. Importantly, the facile, low-cost, high-yield, mass-productive "green" process provides enormous advantages for synthesis and application of fluorescent nanocrystals, which will have great impact in nanomaterial technology.
NASA Technical Reports Server (NTRS)
Guit, William J.; Fisher, Dominic
2016-01-01
Presentation reflects EOS Aura mission status, spacecraft subsystems summary, recent and planned activities, inclination adjust maneuvers, propellant usage, orbit maintenance maneuvers, conjunction assessment events, orbital parameters trends and predictions.
The Laboratory Animal Sciences Program manages the expansion, processing, and distribution of1,501 genetically engineered mouse embryonic stem cell (mESC) linesharboring conditional microRNA transgenes. The Laboratory Animal Sciences Prog
Louisiana Airport System Plan Five-Year Capital Improvement Program.
DOT National Transportation Integrated Search
1992-07-01
The Louisiana Airport System Plan (LASP) Five-Year-Capital Improvement Program (CIP) is a development plan for all commercial service, reliever, and general aviation airports in Louisiana. It is a detailed listing of potential projects based on the a...
A Functional Data Model Realized: LaTiS Deployments
NASA Astrophysics Data System (ADS)
Baltzer, T.; Lindholm, D. M.; Wilson, A.; Putnam, B.; Christofferson, R.; Flores, N.; Roughton, S.
2016-12-01
At prior AGU annual meetings, members of the University of Colorado Laboratory for Atmospheric and Space Physics (LASP) Web Team have described work being done on a functional data model and the software framework called LaTis, that implements it. This presentation describes the evolution of LaTiS and presents several instances of LaTiS in operation today that demonstrate its various capabilities. With LaTiS, serving a new dataset can be a simple as adding a small descriptor file. From providing access to spacecraft telemetry data in a variety of forms for the LASP missions operation group, to providing access to scientific data for the MMS and MAVEN science teams, to server-side functionality such as fusing satellite visible and infrared data along with forecast model data into a Geotiff image for situational awareness purposes, LaTiS has demonstrated itself as a highly flexible, standards-based framework that provides easy data access, dynamic reformatting, and customizable server side functionality.
EOS Aqua Mission Status at Earth Science Constellation MOWG Meeting @ LASP April 13, 2016
NASA Technical Reports Server (NTRS)
Guit, William J.
2016-01-01
This presentation reflects the EOS Aqua mission status, spacecraft subsystem summary, recent and planned activities, inclination adjust maneuvers, propellant usage and lifetime estimate, orbital maintenance maneuvers, conjunction assessment high interest events, ground track error, spacecraft orbital parameters trends and predictions.
Tormenta Espacial: Engaging Spanish Speakers in the Planetarium and K-12 Classroom
NASA Astrophysics Data System (ADS)
Salas, F.; Duncan, D.; Traub-Metlay, S.
2008-06-01
Reaching out to Spanish speakers is increasingly vital to workforce development and public support of space science projects. Building on a successful partnership with NASA's TIMED mission, LASP and Space Science Institute, Fiske Planetarium has translated its original planetarium show - ``Space Storm'' - into ``Tormenta Espacial.''
The Laboratory Animal Sciences Program will breed 24 KPC mice will be bred with the intent of generating a cohort of 18 animals with confirmed tumor-load matching the following enrollment criteria:female mice are considered eligible for enrollm
The Louisiana Accelerated Schools Project First Year Evaluation Report.
ERIC Educational Resources Information Center
St. John, Edward P.; And Others
The Louisiana Accelerated Schools Project (LASP) is a statewide network of schools that are changing from the traditional mode of schooling for at-risk students, which stresses remediation, to one of acceleration, which stresses accelerated learning for all students. The accelerated schools process provides a systematic approach to the…
The Laboratory Animal Sciences Program will breed 18 KPC animals with the intent of generating a cohort of 12 animals with confirmed tumor-load matching the following enrollment criteria:female mice are considered eligible for enrollment when u
The Laboratory Animal Sciences Program will induce breed 50 KPC animals with the intent of generating a cohort of 40 animals with confirmed tumor-load matching the following enrollment criteria:female mice are considered eligible for enrollment
Gender differences in D-aspartic acid content in skull bone.
Torikoshi-Hatano, Aiko; Namera, Akira; Shiraishi, Hiroaki; Arima, Yousuke; Toubou, Hirokazu; Ezaki, Jiro; Morikawa, Masami; Nagao, Masataka
2012-12-01
In forensic medicine, the personal identification of cadavers is one of the most important tasks. One method of estimating age at death relies on the high correlation between racemization rates in teeth and actual age, and this method has been applied successfully in forensic odontology for several years. In this study, we attempt to facilitate the analysis of racemized amino acids and examine the determination of age at death on the basis of the extent of aspartic acid (Asp) racemization in skull bones. The specimens were obtained from 61 human skull bones (19 females and 42 males) that underwent judicial autopsy from October 2010 to May 2012. The amount of D-Asp and L-Asp, total protein, osteocalcin, and collagen I in the skull bones was measured. Logistic regression analysis was performed for age, sex, and each measured protein. The amount of D-Asp in the female skull bones was significantly different from that in the male skull bones (p = 0.021), whereas the amount of L-Asp was similar. Thus, our study indicates that the amount of D-Asp in skull bones is different between the sexes.
NASA Astrophysics Data System (ADS)
Palo, S. E.; Li, X.; Woods, T. N.; Kohnert, R.
2014-12-01
There is a long history of cooperation between students at the University of Colorado, Boulder and professional engineers and scientists at LASP, which has led to many successful space missions with direct student involvement. The recent student-led missions include the Student Nitric Oxide Explorer (SNOE, 1998 - 2002), the Student Dust Counter (SDC) on New Horizons (2006 - present), the Colorado Student Space Weather Experiment (CSSWE), being a very successful NSF CubeSat that launched in September 2012, and the NASA Miniature X-ray Solar Spectrometer (MinXSS) CubeSat (launch will be in early 2015). Students are involved in all aspects of the design, and they experience the full scope of the mission process from concept, to fabrication and test, and mission operations. A significant part of the student involvement in the CubeSat projects is gained by using the CubeSat development as a focal point for an existing two-semester course sequence in CU's Aerospace Engineering Sciences (AES) Department: the Space Hardware Design section of Graduate Projects I & II (ASEN 5018 & ASEN 6028). The goal of these courses is to teach graduate students how to design and build systems using a requirement-based approach and fundamental systems engineering practices. The two-semester sequence takes teams of about 15 students from requirements definition and preliminary design through manufacturing, integration, and testing. In addition to the design process, students learn key professional skills such as working effectively in groups, finding solutions to open-ended problems, and actually building a system to their own set of specifications. The partnership between AES and LASP allows us to include engineering professionals in the mix, thus more effectively training science and engineering students for future roles in the civilian or commercial space industry. The mentoring process with LASP engineers helps to mitigate risk of the inexperience of the students and ensures consistent system engineer oversight for the multi-year CubeSat programs.
The Laboratory Animal Sciences Program will breed 25 KPC animals with the intent of generating a cohort of 20 animals with confirmed tumor-load matching the following enrollment criteria:female mice are considered eligible for enrollment when u
NASA Technical Reports Server (NTRS)
1992-01-01
A non-destructive testing system, originally developed for Langley Research Center, is sold commercially. The DyLASP Profilometer locates defects in composite and metallic materials and assemblies. It operates in real time and displays results as a contour map of the assembly with defects indicated by size and location. Applications are in non-destructive testing and evaluation, and the company will customize to user requirements.
75 FR 18255 - Passenger Facility Charge Database System for Air Carrier Reporting
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-09
... Facility Charge Database System for Air Carrier Reporting AGENCY: Federal Aviation Administration (FAA... the Passenger Facility Charge (PFC) database system to report PFC quarterly report information. In... developed a national PFC database system in order to more easily track the PFC program on a nationwide basis...
Effective amino acid composition of seaweeds inducing food preference behaviors in Aplysia kurodai.
Nagahama, Tatsumi; Fujimoto, Kiyo; Takami, Shigemi; Kinugawa, Aiko; Narusuye, Kenji
2009-07-01
Aplysia kurodai feeds on Ulva but rejects Gelidium and Pachydictyon with distinct patterned jaw movements. We previously demonstrated that these movements are induced by taste alone. Thus some chemicals may contribute to induction of these responses. We explored the amino acids composition of Ulva, Gelidium and Pachydictyon extracts used during our taste-induced physiological experiments. These solutions contained many constituents. The concentrations of six amino acids (Asp, Asn, Glu, Gln, Phe, Tau) were obviously different in the three extract solutions. We explored patterned jaw movements following application of solutions containing a pure amino acid. We statistically compared the occurrence numbers of ingestion-like and rejection-like patterned jaw movements (positive and negative values, respectively) for each amino acid. Our results suggested that L-Asn tends to induce ingestion-like responses, likely resulting in a preference of Ulva. In contrast, L-Asp tends to induce rejection-like responses, likely resulting in aversion towards Pachydictyon. In addition, we demonstrated that L-Asn and L-Asp solutions were sufficient to induce muscle activity associated with ingestion-like or rejection-like responses in the jaw muscles of a semi-intact preparation.
The MMS Science Data Center: Operations, Capabilities, and Resource.
NASA Astrophysics Data System (ADS)
Larsen, K. W.; Pankratz, C. K.; Giles, B. L.; Kokkonen, K.; Putnam, B.; Schafer, C.; Baker, D. N.
2015-12-01
The Magnetospheric MultiScale (MMS) constellation of satellites completed their six month commissioning period in August, 2015 and began science operations. Science operations for the Solving Magnetospheric Acceleration, Reconnection, and Turbulence (SMART) instrument package occur at the Laboratory for Atmospheric and Space Physics (LASP). The Science Data Center (SDC) at LASP is responsible for the data production, management, distribution, and archiving of the data received. The mission will collect several gigabytes per day of particles and field data. Management of these data requires effective selection, transmission, analysis, and storage of data in the ground segment of the mission, including efficient distribution paths to enable the science community to answer the key questions regarding magnetic reconnection. Due to the constraints on download volume, this includes the Scientist-in-the-Loop program that identifies high-value science data needed to answer the outstanding questions of magnetic reconnection. Of particular interest to the community is the tools and associated website we have developed to provide convenient access to the data, first by the mission science team and, beginning March 1, 2016, by the entire community. This presentation will demonstrate the data and tools available to the community via the SDC and discuss the technologies we chose and lessons learned.
NASA Astrophysics Data System (ADS)
Eparvier, F. G.; McCaffrey, M. S.; Buhr, S. M.
2008-12-01
With the aim of meeting NASA goals for education and public outreach as well as support education reform efforts including the National Science Education Standards, a suite of education materials and strategies have been developed by the Cooperative Institute for Environmental Sciences (CIRES) with the Laboratory for Atmospheric and Space Physics (LASP) at the University of Colorado for the Extreme Ultraviolet Variability Experiment (EVE), which is an instrument aboard the Solar Dynamic Observatory. This paper will examine the education materials that have been developed for teachers in the classroom and scientists who are conducting outreach, including handouts, a website on space weather for teachers, a slideshow presentation about the overall Solar Dynamic Observatory mission, and a DVD with videos explaining the construction and goals of the EVE instrument, a tour of LASP, and an overview of space science careers. The results and potential transferability of a pilot project developed through this effort that engaged English Second Language learners in a semester-long course on space weather that incorporated the used of a Sudden Ionospheric Disturbance (SID) Monitor will be highlighted.
Yujiao, Wu; Guoyan, Wang; Wenyan, Zhao; Hongfen, Zhang; Huanwang, Jing; Anjia, Chen
2014-05-01
In this paper, a simple, effective and green capillary electrophoresis separation and detection method was developed for the quantification of underivatized amino acids (dl-phenylalanine; dl-tryptophan) using β-Cyclodextrin and chiral ionic liquid ([TBA] [l-ASP]) as selectors. Separation parameters such as buffer concentrations, pH, β-CD and chiral ionic liquid concentrations and separation voltage were investigated for the enantioseparation in order to achieve the maximum possible resolution. A good separation was achieved in a background electrolyte composed of 15 mm sodium tetraborate, 5 mm β-CD and 4 mm chiral ionic liquid at pH 9.5, and an applied voltage of 10 kV. Under optimum conditions, linearity was achieved within concentration ranges from 0.08 to 10 µg/mL for the analytes with correlation coefficients from 0.9956 to 0.9998, and the analytes were separated in less than 6 min with efficiencies up to 970,000 plates/m. The proposed method was successfully applied to the determination of amino acid enantiomers in compound amino acids injections, such as 18AA-I, 18AA-II and 3AA.
The Laboratory Animal Sciences Program will assess the in vitro potency of candidate compounds via a conventional cell-based toxicity assay (XTT living cell test) in a series of six drug concentrations (ranging from 0.1 nM to 50,000 nM) of a single a
Elsayed, Mahmoud; Hsiung, Ming C; Meggo-Quiroz, L David; Elguindy, Mostafa; Uygur, Begum; Tandon, Rohit; Guvenc, Tolga; Keser, Nurgul; Vural, Mustafa G; Bulur, Serkan; Chahwala, Jugal R; Abtahi, Firoozeh; Nanda, Navin C
2015-12-01
An atrial septal pouch (ASP) results from partial fusion of the septum primum and the septum secundum, and depending on the site of fusion, the pouch can be left-sided (LASP) or right-sided (RASP). LASPs have been described in association with thrombi found in patients admitted with acute strokes, raising awareness of its potential cardioembolic role, especially in those with no other clearly identifiable embolic source. We retrospectively studied 39 patients in whom the presence of an ASP had been identified by three-dimensional transesophageal echocardiography (3DTEE) and who had a two-dimensional transesophageal echocardiogram (2DTEE) performed during the same clinical encounter. The incremental value provided by 3DTEE over 2DTEE included the detection of six ASPs not found by 2DTEE; the detection of two ASPs in the same subject (in four patients) not identified by 2DTEE; larger ASP measurements of length and height in over 80% of the cases; and measurement of the ASP width (elevational axis) for the calculation of the area of the ASP opening, because of its unique capability to view the pouch en face. In addition, the volume of ASP and of the echogenic masses contained in the ASP (four of 39 patients) could be calculated by 3DTEE, which is a superior parameter of size characterization when compared to individual dimensions. One of these patients who presented with ischemic stroke diagnosed by magnetic resonance imaging had a large (>2 cm) mass in a LASP, with echolucencies similar to those seen in thrombi and associated with clot lysis and resolution. This mass completely disappeared on anticoagulant therapy lending credence that it was most likely a thrombus. There was no history of stroke or any other type of embolic event in the other three patients with masses in ASP. In conclusion, this retrospective study highlights the incremental value of 3DTEE over 2DTEE in the comprehensive assessment and characterization of ASPs, which can aid in the clarification of their role in cryptogenic stroke patients. © 2015, Wiley Periodicals, Inc.
Treno, Concetta; Gironi Carnevale, Ugo A.; Arra, Claudio; Nieddu, Maria; Pagano, Cristina; Illiano, Placido; Barbato, Fabiana; Carboni, Ezio; Laviola, Giovanni; Lacivita, Enza; Leopoldo, Marcello; Adriani, Walter; Sadile, Adolfo G.
2014-01-01
The cross-talk at the prefronto-striatal interface involves excitatory amino acids, different receptors, transducers and modulators. We investigated long-term effects of a prepuberal, subchronic 5-HT7-R agonist (LP-211) on adult behaviour, amino acids and synaptic markers in a model for Attention-Deficit/Hyperactivity Disorder (ADHD). Naples High Excitability rats (NHE) and their Random Bred controls (NRB) were daily treated with LP-211 in the 5th and 6th postnatal week. One month after treatment, these rats were tested for indices of activity, non selective (NSA), selective spatial attention (SSA) and emotionality. The quantity of L-Glutamate (L-Glu), L-Aspartate (L-Asp) and L-Leucine (L-Leu), dopamine transporter (DAT), NMDAR1 subunit and CAMKIIα, were assessed in prefrontal cortex (PFC), dorsal (DS) and ventral striatum (VS), for their role in synaptic transmission, neural plasticity and information processing. Prepuberal LP-211 (at lower dose) reduced horizontal activity and (at higher dose) increased SSA, only for NHE but not in NRB rats. Prepuberal LP-211 increased, in NHE rats, L-Glu in the PFC and L-Asp in the VS (at 0.250 mg/kg dose), whereas (at 0.125 mg/kg dose) it decreased L-Glu and L-Asp in the DS. The L-Glu was decreased, at 0.125 mg/kg, only in the VS of NRB rats. The DAT levels were decreased with the 0.125 mg/kg dose (in the PFC), and increased with the 0.250 mg/kg dose (in the VS), significantly for NHE rats. The basal NMDAR1 level was higher in the PFC of NHE than NRB rats; LP-211 treatment (at 0.125 mg/kg dose) decreased NMDAR1 in the VS of NRB rats. This study represents a starting point about the impact of developmental 5-HT7-R activation on neuro-physiology of attentive processes, executive functions and their neural substrates. PMID:24709857
GOES EXIS Quadruplets Together in a Clean Room "Nursery"
2014-02-10
Four Extreme Ultraviolet and X-ray Irradiance Sensors or EXIS instruments that will fly aboard four of NOAA's Geostationary Operational Environmental Satellite-R or GOES-R Series spacecraft were recently lined up like babies in a nursery. The EXIS Team at NOAA's Laboratory for Atmospheric and Space Physics (LASP) in Boulder, Colorado took a short timeout during the week of January 20, 2014 to take advantage of a rare photo opportunity. Each EXIS instrument will fly aboard one of the GOES-R series of spacecraft that include GOES-R, S, T, and U. All four EXIS instruments happened to be in the clean room at the same time. It is expected that this will probably be the last time that all four siblings will be in one place together as Flight Model 1 (seen on the left) is being shipped on February 3 to begin integration and testing onto the GOES-R spacecraft at a Lockheed Martin facility in Littleton, Colo. The other instruments have already dispersed to other areas at LASP for continued build and test operations. The EXIS instruments on the GOES-R series satellites are critical to understanding and monitoring solar irradiance in the upper atmosphere, that is, the power and effect of the Sun’s electromagnetic radiation per unit of area. EXIS will be able to detect solar flares that could interrupt communications and reduce navigational accuracy, affecting satellites, high altitude airlines and power grids on Earth. On board the EXIS are two main sensors, the Extreme Ultraviolet Sensor (EUVS) and the X-Ray Sensor (XRS), which will help scientists monitor activity on the sun. The GOES-R series is a collaborative development and acquisition effort between the National Oceanic and Atmospheric Administration and NASA. The GOES-R satellites will provide continuous imagery and atmospheric measurements of Earth’s Western Hemisphere and space weather monitoring. For more information about the GOES-R series, visit: www.goes-r.gov Credit: NOAA/NASA NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram
EPA Facility Registry Service (FRS): OIL
This dataset contains location and facility identification information from EPA's Facility Registry Service (FRS) for the subset of facilities that link to the Oil database. The Oil database contains information on Spill Prevention, Control, and Countermeasure (SPCC) and Facility Response Plan (FRP) subject facilities to prevent and respond to oil spills. FRP facilities are referred to as substantial harm facilities due to the quantities of oil stored and facility characteristics. FRS identifies and geospatially locates facilities, sites or places subject to environmental regulations or of environmental interest. Using vigorous verification and data management procedures, FRS integrates facility data from EPA's national program systems, other federal agencies, and State and tribal master facility records and provides EPA with a centrally managed, single source of comprehensive and authoritative information on facilities. This data set contains the subset of FRS integrated facilities that link to Oil facilities once the Oil data has been integrated into the FRS database. Additional information on FRS is available at the EPA website https://www.epa.gov/enviro/facility-registry-service-frs.
Elleuch, Nabil; Amamou, Walid; Ben Ahmed, Ali; Abid, Younes; Feki, Habib
2014-07-15
Single crystals of L-asparaginium picrate (LASP) were grown by slow evaporation technique at room temperature and were the subject of an X-ray powder diffraction study to confirm the crystalline nature of the synthesized compound. FT-IR and Raman spectra were recorded and analyzed with the aid of the density functional theory (DFT) calculations in order to make a suitable assignment of the observed bands. The optimum molecular geometry, normal mode wavenumbers, infrared and Raman intensities and the first hyperpolarizability were investigated with the help of B3LYP method using 6-31G(d) basis set. The theoretical FT-IR and Raman spectra of LASP were simulated and compared with the experimental data. A good agreement was shown and a reliable vibrational assignment was made. Natural bond orbital (NBO) analysis was carried out to demonstrate the various inter and intramolecular interactions that are responsible for the stabilization of the title compound leading to high NLO activity. A study on the electronic properties was performed by time-dependent DFT (TD-DFT) approach. The lowering in the HOMO and LUMO energy gap explains the eventual charge transfer interactions that take place within the molecules. Copyright © 2014 Elsevier B.V. All rights reserved.
Onishi, Yohei; Prihanto, Asep A; Yano, Shigekazu; Takagi, Kazuyoshi; Umekawa, Midori; Wakayama, Mamoru
2015-10-01
It has been reported that acrylamide, a potential carcinogen, is formed from the reaction of L-asparagine (L-Asn) and reducing sugars contained in foods during heating processes and free asparagine is a limiting factor for acrylamide formation. It has been reported that potato products such as potato chips, which are made through heating processes, contain high levels of acrylamide. To decrease the amount of L-Asn in potatoes using L-asparaginase, effective treatment conditions of sliced potatoes with the enzyme have been investigated. By treating sliced potatoes with Bacillus subtilis L-asparaginase II (BAsnase; 4 U/g potato), appriximately 40 % of L-Asn in the sliced potatoes was converted into L-aspartic acid (L-Asp). To make this enzyme more effective, prior to enzymatic treatment, sliced potatoes were freeze-thawed, dried at 90 °C for 20 min, and vacuum treated for 10 min under decompressed condition, resulting in the hydrolysis of approximately 90 % of L-Asn to L-Asp. The acrylamide content of BAsnase-treated fried potato chips decreased to below 20 % of that of BAsnase-untreated fried potato chips. Treatment conditions examined in this study were found to be effective to suppress the formation of acrylamide in fried potato chips.
NASA Technical Reports Server (NTRS)
Davis, Randal; Thalman, Nancy
1993-01-01
The University of Colorado's Laboratory for Atmospheric and Space Physics (CU/LASP) along with the Goddard Space Flight Center (GSFC) and the Jet Propulsion Laboratory (JPL) designed, implemented, tested, and demonstrated a prototype of the distributed, hierarchical planning and scheduling system comtemplated for the Earth Observing System (EOS) project. The planning and scheduling prototype made use of existing systems: CU/LASP's Operations and Science Instrument Support Planning and Scheduling (OASIS-PS) software package; GSFC's Request Oriented Scheduling Engine (ROSE); and JPL's Plan Integrated Timeliner 2 (Plan-It-2). Using these tools, four scheduling nodes were implemented and tied together using a new communications protocol for scheduling applications called the Scheduling Applications Interface Language (SAIL). An extensive and realistic scenario of EOS satellite operations was then developed and the prototype scheduling system was tested and demonstrated using the scenario. Two demonstrations of the system were given to NASA personnel and EOS core system (ECS) contractor personnel. A comprehensive volume of lessons learned was generated and a meeting was held with NASA and ECS representatives to review these lessons learned. A paper and presentation on the project's final results was given at the American Institute of Aeronautics and Astronautics Computing in Aerospace 9 conference.
Alcantara, Luiz Carlos Junior; Cassol, Sharon; Libin, Pieter; Deforche, Koen; Pybus, Oliver G; Van Ranst, Marc; Galvão-Castro, Bernardo; Vandamme, Anne-Mieke; de Oliveira, Tulio
2009-07-01
Human immunodeficiency virus type-1 (HIV-1), hepatitis B and C and other rapidly evolving viruses are characterized by extremely high levels of genetic diversity. To facilitate diagnosis and the development of prevention and treatment strategies that efficiently target the diversity of these viruses, and other pathogens such as human T-lymphotropic virus type-1 (HTLV-1), human herpes virus type-8 (HHV8) and human papillomavirus (HPV), we developed a rapid high-throughput-genotyping system. The method involves the alignment of a query sequence with a carefully selected set of pre-defined reference strains, followed by phylogenetic analysis of multiple overlapping segments of the alignment using a sliding window. Each segment of the query sequence is assigned the genotype and sub-genotype of the reference strain with the highest bootstrap (>70%) and bootscanning (>90%) scores. Results from all windows are combined and displayed graphically using color-coded genotypes. The new Virus-Genotyping Tools provide accurate classification of recombinant and non-recombinant viruses and are currently being assessed for their diagnostic utility. They have incorporated into several HIV drug resistance algorithms including the Stanford (http://hivdb.stanford.edu) and two European databases (http://www.umcutrecht.nl/subsite/spread-programme/ and http://www.hivrdb.org.uk/) and have been successfully used to genotype a large number of sequences in these and other databases. The tools are a PHP/JAVA web application and are freely accessible on a number of servers including: http://bioafrica.mrc.ac.za/rega-genotype/html/, http://lasp.cpqgm.fiocruz.br/virus-genotype/html/, http://jose.med.kuleuven.be/genotypetool/html/.
Nuclear Energy Infrastructure Database Description and User’s Manual
DOE Office of Scientific and Technical Information (OSTI.GOV)
Heidrich, Brenden
In 2014, the Deputy Assistant Secretary for Science and Technology Innovation initiated the Nuclear Energy (NE)–Infrastructure Management Project by tasking the Nuclear Science User Facilities, formerly the Advanced Test Reactor National Scientific User Facility, to create a searchable and interactive database of all pertinent NE-supported and -related infrastructure. This database, known as the Nuclear Energy Infrastructure Database (NEID), is used for analyses to establish needs, redundancies, efficiencies, distributions, etc., to best understand the utility of NE’s infrastructure and inform the content of infrastructure calls. The Nuclear Science User Facilities developed the database by utilizing data and policy direction from amore » variety of reports from the U.S. Department of Energy, the National Research Council, the International Atomic Energy Agency, and various other federal and civilian resources. The NEID currently contains data on 802 research and development instruments housed in 377 facilities at 84 institutions in the United States and abroad. The effort to maintain and expand the database is ongoing. Detailed information on many facilities must be gathered from associated institutions and added to complete the database. The data must be validated and kept current to capture facility and instrumentation status as well as to cover new acquisitions and retirements. This document provides a short tutorial on the navigation of the NEID web portal at NSUF-Infrastructure.INL.gov.« less
Aircraft Measurements for Understanding Air-Sea Coupling and Improving Coupled Model Predictions
2014-09-30
layer thermodynamic properties across the DYNAMO domain during the suppressed and active phase of MJO; and 3) variability and distribution of upper ocean...structure during suppressed, active and restoring phase of MJO. One of the unique aspects of LASP/ DYNAMO WP-3D project was to supplement the point...observations by probing the atmospheric and oceanic variability across the DYNAMO domain. Adhering to this aspect, vertical cross section of lower
An Investigation of Turbulent Heat Exchange in the Subtropics
2014-09-30
meteorological sensors aboard the research vessel the R/V Revelle during the DYNAMO field program. In situ meteorology and high-rate flux sensors operated...continuously while in the sampling period for DYNAMO Leg 3. This included all sensors operating during Leg 2 with the addition of a closed-path LI...stress; wave data; surface and near surface sea temperatures, salinity and currents; and other key variables specifically requested by DYNAMO /LASP PIs
[Quality management and participation into clinical database].
Okubo, Suguru; Miyata, Hiroaki; Tomotaki, Ai; Motomura, Noboru; Murakami, Arata; Ono, Minoru; Iwanaka, Tadashi
2013-07-01
Quality management is necessary for establishing useful clinical database in cooperation with healthcare professionals and facilities. The ways of management are 1) progress management of data entry, 2) liaison with database participants (healthcare professionals), and 3) modification of data collection form. In addition, healthcare facilities are supposed to consider ethical issues and information security for joining clinical databases. Database participants should check ethical review boards and consultation service for patients.
Stromal Gene Expression and Function in Primary Breast Tumors that Metastasize to Bone Cancer
2006-07-01
surrounding bone microenvironment were investigated by purifying endothelial cells from tumor-burdened and non-tumor burdened spines . 4T1...of Balb/c mice. Fresh resected tissue (normal fat pad, primary tumor tissue or the metastatic sites spine , femur and lung) was obtained and cell... Hedgehog signalling pathway: Lasp1, CREBBP/EP300 inhibitory protein 1 and FoxP1. Of interest as well are a number of differentially regulated ESTs
FY11 Facility Assessment Study for Aeronautics Test Program
NASA Technical Reports Server (NTRS)
Loboda, John A.; Sydnor, George H.
2013-01-01
This paper presents the approach and results for the Aeronautics Test Program (ATP) FY11 Facility Assessment Project. ATP commissioned assessments in FY07 and FY11 to aid in the understanding of the current condition and reliability of its facilities and their ability to meet current and future (five year horizon) test requirements. The principle output of the assessment was a database of facility unique, prioritized investments projects with budgetary cost estimates. This database was also used to identify trends for the condition of facility systems.
National Transportation Atlas Databases : 1999
DOT National Transportation Integrated Search
1999-01-01
The National Transportation Atlas Databases -- 1999 (NTAD99) is a set of national : geographic databases of transportation facilities. These databases include geospatial : information for transportation modal networks and intermodal terminals, and re...
National Transportation Atlas Databases : 2001
DOT National Transportation Integrated Search
2001-01-01
The National Transportation Atlas Databases-2001 (NTAD-2001) is a set of national geographic databases of transportation facilities. These databases include geospatial information for transportation modal networks and intermodal terminals and related...
National Transportation Atlas Databases : 1996
DOT National Transportation Integrated Search
1996-01-01
The National Transportation Atlas Databases -- 1996 (NTAD96) is a set of national : geographic databases of transportation facilities. These databases include geospatial : information for transportation modal networks and intermodal terminals, and re...
National Transportation Atlas Databases : 2000
DOT National Transportation Integrated Search
2000-01-01
The National Transportation Atlas Databases-2000 (NTAD-2000) is a set of national geographic databases of transportation facilities. These databases include geospatial information for transportation modal networks and intermodal terminals and related...
National Transportation Atlas Databases : 1997
DOT National Transportation Integrated Search
1997-01-01
The National Transportation Atlas Databases -- 1997 (NTAD97) is a set of national : geographic databases of transportation facilities. These databases include geospatial : information for transportation modal networks and intermodal terminals, and re...
Protocol for the E-Area Low Level Waste Facility Disposal Limits Database
DOE Office of Scientific and Technical Information (OSTI.GOV)
Swingle, R
2006-01-31
A database has been developed to contain the disposal limits for the E-Area Low Level Waste Facility (ELLWF). This database originates in the form of an EXCEL{copyright} workbook. The pertinent sheets are translated to PDF format using Adobe ACROBAT{copyright}. The PDF version of the database is accessible from the Solid Waste Division web page on SHRINE. In addition to containing the various disposal unit limits, the database also contains hyperlinks to the original references for all limits. It is anticipated that database will be revised each time there is an addition, deletion or revision of any of the ELLWF radionuclidemore » disposal limits.« less
47 CFR 15.713 - TV bands database.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 47 Telecommunication 1 2010-10-01 2010-10-01 false TV bands database. 15.713 Section 15.713... TV bands database. (a) Purpose. The TV bands database serves the following functions: (1) To... databases. (b) Information in the TV bands database. (1) Facilities already recorded in Commission databases...
Scofield, Patricia A.; Smith, Linda Lenell; Johnson, David N.
2017-07-01
The U.S. Environmental Protection Agency promulgated national emission standards for emissions of radionuclides other than radon from US Department of Energy facilities in Chapter 40 of the Code of Federal Regulations (CFR) 61, Subpart H. This regulatory standard limits the annual effective dose that any member of the public can receive from Department of Energy facilities to 0.1 mSv. As defined in the preamble of the final rule, all of the facilities on the Oak Ridge Reservation, i.e., the Y–12 National Security Complex, Oak Ridge National Laboratory, East Tennessee Technology Park, and any other U.S. Department of Energy operations onmore » Oak Ridge Reservation, combined, must meet the annual dose limit of 0.1 mSv. At Oak Ridge National Laboratory, there are monitored sources and numerous unmonitored sources. To maintain radiological source and inventory information for these unmonitored sources, e.g., laboratory hoods, equipment exhausts, and room exhausts not currently venting to monitored stacks on the Oak Ridge National Laboratory campus, the Environmental Protection Rad NESHAPs Inventory Web Database was developed. This database is updated annually and is used to compile emissions data for the annual Radionuclide National Emission Standards for Hazardous Air Pollutants (Rad NESHAPs) report required by 40 CFR 61.94. It also provides supporting documentation for facility compliance audits. In addition, a Rad NESHAPs source and dose database was developed to import the source and dose summary data from Clean Air Act Assessment Package—1988 computer model files. As a result, this database provides Oak Ridge Reservation and facility-specific source inventory; doses associated with each source and facility; and total doses for the Oak Ridge Reservation dose.« less
Scofield, Patricia A; Smith, Linda L; Johnson, David N
2017-07-01
The U.S. Environmental Protection Agency promulgated national emission standards for emissions of radionuclides other than radon from US Department of Energy facilities in Chapter 40 of the Code of Federal Regulations (CFR) 61, Subpart H. This regulatory standard limits the annual effective dose that any member of the public can receive from Department of Energy facilities to 0.1 mSv. As defined in the preamble of the final rule, all of the facilities on the Oak Ridge Reservation, i.e., the Y-12 National Security Complex, Oak Ridge National Laboratory, East Tennessee Technology Park, and any other U.S. Department of Energy operations on Oak Ridge Reservation, combined, must meet the annual dose limit of 0.1 mSv. At Oak Ridge National Laboratory, there are monitored sources and numerous unmonitored sources. To maintain radiological source and inventory information for these unmonitored sources, e.g., laboratory hoods, equipment exhausts, and room exhausts not currently venting to monitored stacks on the Oak Ridge National Laboratory campus, the Environmental Protection Rad NESHAPs Inventory Web Database was developed. This database is updated annually and is used to compile emissions data for the annual Radionuclide National Emission Standards for Hazardous Air Pollutants (Rad NESHAPs) report required by 40 CFR 61.94. It also provides supporting documentation for facility compliance audits. In addition, a Rad NESHAPs source and dose database was developed to import the source and dose summary data from Clean Air Act Assessment Package-1988 computer model files. This database provides Oak Ridge Reservation and facility-specific source inventory; doses associated with each source and facility; and total doses for the Oak Ridge Reservation dose.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Scofield, Patricia A.; Smith, Linda Lenell; Johnson, David N.
The U.S. Environmental Protection Agency promulgated national emission standards for emissions of radionuclides other than radon from US Department of Energy facilities in Chapter 40 of the Code of Federal Regulations (CFR) 61, Subpart H. This regulatory standard limits the annual effective dose that any member of the public can receive from Department of Energy facilities to 0.1 mSv. As defined in the preamble of the final rule, all of the facilities on the Oak Ridge Reservation, i.e., the Y–12 National Security Complex, Oak Ridge National Laboratory, East Tennessee Technology Park, and any other U.S. Department of Energy operations onmore » Oak Ridge Reservation, combined, must meet the annual dose limit of 0.1 mSv. At Oak Ridge National Laboratory, there are monitored sources and numerous unmonitored sources. To maintain radiological source and inventory information for these unmonitored sources, e.g., laboratory hoods, equipment exhausts, and room exhausts not currently venting to monitored stacks on the Oak Ridge National Laboratory campus, the Environmental Protection Rad NESHAPs Inventory Web Database was developed. This database is updated annually and is used to compile emissions data for the annual Radionuclide National Emission Standards for Hazardous Air Pollutants (Rad NESHAPs) report required by 40 CFR 61.94. It also provides supporting documentation for facility compliance audits. In addition, a Rad NESHAPs source and dose database was developed to import the source and dose summary data from Clean Air Act Assessment Package—1988 computer model files. As a result, this database provides Oak Ridge Reservation and facility-specific source inventory; doses associated with each source and facility; and total doses for the Oak Ridge Reservation dose.« less
EPA Facility Registry Service (FRS): Facility Interests Dataset - Intranet
This web feature service consists of location and facility identification information from EPA's Facility Registry Service (FRS) for all sites that are available in the FRS individual feature layers. The layers comprise the FRS major program databases, including:Assessment Cleanup and Redevelopment Exchange System (ACRES) : brownfields sites ; Air Facility System (AFS) : stationary sources of air pollution ; Air Quality System (AQS) : ambient air pollution data from monitoring stations; Bureau of Indian Affairs (BIA) : schools data on Indian land; Base Realignment and Closure (BRAC) facilities; Clean Air Markets Division Business System (CAMDBS) : market-based air pollution control programs; Comprehensive Environmental Response, Compensation, and Liability Information System (CERCLIS) : hazardous waste sites; Integrated Compliance Information System (ICIS) : integrated enforcement and compliance information; National Compliance Database (NCDB) : Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the Toxic Substances Control Act (TSCA); National Pollutant Discharge Elimination System (NPDES) module of ICIS : NPDES surface water permits; Radiation Information Database (RADINFO) : radiation and radioactivity facilities; RACT/BACT/LAER Clearinghouse (RBLC) : best available air pollution technology requirements; Resource Conservation and Recovery Act Information System (RCRAInfo) : tracks generators, transporters, treaters, storers, and disposers of haz
EPA Facility Registry Service (FRS): Facility Interests Dataset - Intranet Download
This downloadable data package consists of location and facility identification information from EPA's Facility Registry Service (FRS) for all sites that are available in the FRS individual feature layers. The layers comprise the FRS major program databases, including:Assessment Cleanup and Redevelopment Exchange System (ACRES) : brownfields sites ; Air Facility System (AFS) : stationary sources of air pollution ; Air Quality System (AQS) : ambient air pollution data from monitoring stations; Bureau of Indian Affairs (BIA) : schools data on Indian land; Base Realignment and Closure (BRAC) facilities; Clean Air Markets Division Business System (CAMDBS) : market-based air pollution control programs; Comprehensive Environmental Response, Compensation, and Liability Information System (CERCLIS) : hazardous waste sites; Integrated Compliance Information System (ICIS) : integrated enforcement and compliance information; National Compliance Database (NCDB) : Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the Toxic Substances Control Act (TSCA); National Pollutant Discharge Elimination System (NPDES) module of ICIS : NPDES surface water permits; Radiation Information Database (RADINFO) : radiation and radioactivity facilities; RACT/BACT/LAER Clearinghouse (RBLC) : best available air pollution technology requirements; Resource Conservation and Recovery Act Information System (RCRAInfo) : tracks generators, transporters, treaters, storers, and disposers
EPA Facility Registry Service (FRS): Facility Interests Dataset Download
This downloadable data package consists of location and facility identification information from EPA's Facility Registry Service (FRS) for all sites that are available in the FRS individual feature layers. The layers comprise the FRS major program databases, including:Assessment Cleanup and Redevelopment Exchange System (ACRES) : brownfields sites ; Air Facility System (AFS) : stationary sources of air pollution ; Air Quality System (AQS) : ambient air pollution data from monitoring stations; Bureau of Indian Affairs (BIA) : schools data on Indian land; Base Realignment and Closure (BRAC) facilities; Clean Air Markets Division Business System (CAMDBS) : market-based air pollution control programs; Comprehensive Environmental Response, Compensation, and Liability Information System (CERCLIS) : hazardous waste sites; Integrated Compliance Information System (ICIS) : integrated enforcement and compliance information; National Compliance Database (NCDB) : Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the Toxic Substances Control Act (TSCA); National Pollutant Discharge Elimination System (NPDES) module of ICIS : NPDES surface water permits; Radiation Information Database (RADINFO) : radiation and radioactivity facilities; RACT/BACT/LAER Clearinghouse (RBLC) : best available air pollution technology requirements; Resource Conservation and Recovery Act Information System (RCRAInfo) : tracks generators, transporters, treaters, storers, and disposers
EPA Facility Registry Service (FRS): Facility Interests Dataset
This web feature service consists of location and facility identification information from EPA's Facility Registry Service (FRS) for all sites that are available in the FRS individual feature layers. The layers comprise the FRS major program databases, including:Assessment Cleanup and Redevelopment Exchange System (ACRES) : brownfields sites ; Air Facility System (AFS) : stationary sources of air pollution ; Air Quality System (AQS) : ambient air pollution data from monitoring stations; Bureau of Indian Affairs (BIA) : schools data on Indian land; Base Realignment and Closure (BRAC) facilities; Clean Air Markets Division Business System (CAMDBS) : market-based air pollution control programs; Comprehensive Environmental Response, Compensation, and Liability Information System (CERCLIS) : hazardous waste sites; Integrated Compliance Information System (ICIS) : integrated enforcement and compliance information; National Compliance Database (NCDB) : Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the Toxic Substances Control Act (TSCA); National Pollutant Discharge Elimination System (NPDES) module of ICIS : NPDES surface water permits; Radiation Information Database (RADINFO) : radiation and radioactivity facilities; RACT/BACT/LAER Clearinghouse (RBLC) : best available air pollution technology requirements; Resource Conservation and Recovery Act Information System (RCRAInfo) : tracks generators, transporters, treaters, storers, and disposers of haz
Naval Air Systems Command Mobile Facility Program
2009-11-03
Julie Trossbach 301-757-3073 Database Manager – Emi McCutcheon 301-757- 8347 BFM – Michelle Moorman 301-757-8328 Comptroller Analyst – Kathy...Jamie McDonald (757) 444-1428 NAVAIR Mobile Facilities MFTool/Database AIR 6.7.6.2 Emi McCutcheon (301) 757-8347 NAVAIR Mobile Facilities Logistics...requirement for mobile trailer -type vans for peculiar jet aircraft maintenance – Needed dust free, temperature & humidity-controlled maintenance
Nuclear Energy Infrastructure Database Fitness and Suitability Review
DOE Office of Scientific and Technical Information (OSTI.GOV)
Heidrich, Brenden
In 2014, the Deputy Assistant Secretary for Science and Technology Innovation (NE-4) initiated the Nuclear Energy-Infrastructure Management Project by tasking the Nuclear Science User Facilities (NSUF) to create a searchable and interactive database of all pertinent NE supported or related infrastructure. This database will be used for analyses to establish needs, redundancies, efficiencies, distributions, etc. in order to best understand the utility of NE’s infrastructure and inform the content of the infrastructure calls. The NSUF developed the database by utilizing data and policy direction from a wide variety of reports from the Department of Energy, the National Research Council, themore » International Atomic Energy Agency and various other federal and civilian resources. The NEID contains data on 802 R&D instruments housed in 377 facilities at 84 institutions in the US and abroad. A Database Review Panel (DRP) was formed to review and provide advice on the development, implementation and utilization of the NEID. The panel is comprised of five members with expertise in nuclear energy-associated research. It was intended that they represent the major constituencies associated with nuclear energy research: academia, industry, research reactor, national laboratory, and Department of Energy program management. The Nuclear Energy Infrastructure Database Review Panel concludes that the NSUF has succeeded in creating a capability and infrastructure database that identifies and documents the major nuclear energy research and development capabilities across the DOE complex. The effort to maintain and expand the database will be ongoing. Detailed information on many facilities must be gathered from associated institutions added to complete the database. The data must be validated and kept current to capture facility and instrumentation status as well as to cover new acquisitions and retirements.« less
DOT National Transportation Integrated Search
2016-10-01
Each database record shows the modes that serve the facility, those that are nearby but not connecting, and incudes facility location information. The data can be analyzed on a city, state, zip code, metropolitan area, or modal basis. Geographic coor...
The Facility Registry System (FRS) is a centrally managed database that identifies facilities, sites or places subject to environmental regulations or of environmental interest. FRS creates high-quality, accurate, and authoritative facility identification records through rigorous...
NASA Astrophysics Data System (ADS)
Volpon, Laurent; Tsan, Pascale; Majer, Zsuzsa; Vass, Elemer; Hollósi, Miklós; Noguéra, Valérie; Lancelin, Jean-Marc; Besson, Françoise
2007-08-01
Iturins are a group of antifungal produced by Bacillus subtilis. All are cyclic lipopeptides with seven α-amino acids of configuration LDDLLDL and one β-amino fatty acid. The bacillomycin L is a member of this family and its NMR structure was previously resolved using the sequence Asp-Tyr-Asn-Ser-Gln-Ser-Thr. In this work, we carefully examined the NMR spectra of this compound and detected an error in the sequence. In fact, Asp1 and Gln5 need to be changed into Asn1 and Glu5, which therefore makes it identical to bacillomycin Lc. As a consequence, it now appears that all iturinic peptides with antibiotic activity share the common β-amino fatty acid 8- L-Asn1- D-Tyr2- D-Asn3 sequence. To better understand the conformational influence of the acidic residue L-Asp1, present, for example in the inactive iturin C, the NMR structure of the synthetic analogue SCP [cyclo ( L-Asp1- D-Tyr2- D-Asn3- L-Ser4- L-Gln5- D-Ser6- L-Thr7-β-Ala8)] was determined and compared with bacillomycin Lc recalculated with the corrected sequence. In both cases, the conformers obtained were separated into two families of similar energy which essentially differ in the number and type of turns. A detailed analysis of both cyclopeptide structures is presented here. In addition, CD and FTIR spectra were performed and confirmed the conformational differences observed by NMR between both cyclopeptides.
National Transportation Atlas Databases : 2002
DOT National Transportation Integrated Search
2002-01-01
The National Transportation Atlas Databases 2002 (NTAD2002) is a set of nationwide geographic databases of transportation facilities, transportation networks, and associated infrastructure. These datasets include spatial information for transportatio...
National Transportation Atlas Databases : 2010
DOT National Transportation Integrated Search
2010-01-01
The National Transportation Atlas Databases 2010 (NTAD2010) is a set of nationwide geographic databases of transportation facilities, transportation networks, and associated infrastructure. These datasets include spatial information for transportatio...
National Transportation Atlas Databases : 2006
DOT National Transportation Integrated Search
2006-01-01
The National Transportation Atlas Databases 2006 (NTAD2006) is a set of nationwide geographic databases of transportation facilities, transportation networks, and associated infrastructure. These datasets include spatial information for transportatio...
National Transportation Atlas Databases : 2005
DOT National Transportation Integrated Search
2005-01-01
The National Transportation Atlas Databases 2005 (NTAD2005) is a set of nationwide geographic databases of transportation facilities, transportation networks, and associated infrastructure. These datasets include spatial information for transportatio...
National Transportation Atlas Databases : 2008
DOT National Transportation Integrated Search
2008-01-01
The National Transportation Atlas Databases 2008 (NTAD2008) is a set of nationwide geographic databases of transportation facilities, transportation networks, and associated infrastructure. These datasets include spatial information for transportatio...
National Transportation Atlas Databases : 2003
DOT National Transportation Integrated Search
2003-01-01
The National Transportation Atlas Databases 2003 (NTAD2003) is a set of nationwide geographic databases of transportation facilities, transportation networks, and associated infrastructure. These datasets include spatial information for transportatio...
National Transportation Atlas Databases : 2004
DOT National Transportation Integrated Search
2004-01-01
The National Transportation Atlas Databases 2004 (NTAD2004) is a set of nationwide geographic databases of transportation facilities, transportation networks, and associated infrastructure. These datasets include spatial information for transportatio...
National Transportation Atlas Databases : 2009
DOT National Transportation Integrated Search
2009-01-01
The National Transportation Atlas Databases 2009 (NTAD2009) is a set of nationwide geographic databases of transportation facilities, transportation networks, and associated infrastructure. These datasets include spatial information for transportatio...
National Transportation Atlas Databases : 2007
DOT National Transportation Integrated Search
2007-01-01
The National Transportation Atlas Databases 2007 (NTAD2007) is a set of nationwide geographic databases of transportation facilities, transportation networks, and associated infrastructure. These datasets include spatial information for transportatio...
National Transportation Atlas Databases : 2012
DOT National Transportation Integrated Search
2012-01-01
The National Transportation Atlas Databases 2012 (NTAD2012) is a set of nationwide geographic databases of transportation facilities, transportation networks, and associated infrastructure. These datasets include spatial information for transportatio...
National Transportation Atlas Databases : 2011
DOT National Transportation Integrated Search
2011-01-01
The National Transportation Atlas Databases 2011 (NTAD2011) is a set of nationwide geographic databases of transportation facilities, transportation networks, and associated infrastructure. These datasets include spatial information for transportatio...
2001-10-25
within one of the programmes sponsored by the European Commission.The system mainly consists of a shared care database in which each groups of...care database in which each community facility, or group of facilities, is supported by a local area network (LAN). Each of these LANs is connected over...functions. The software is layered, so that the client application is not affected by how the servers are implemented or which database system they use
Coordinating Council. First Meeting: NASA/RECON database
NASA Technical Reports Server (NTRS)
1990-01-01
A Council of NASA Headquarters, American Institute of Aeronautics and Astronautics (AIAA), and the NASA Scientific and Technical Information (STI) Facility management met (1) to review and discuss issues of NASA concern, and (2) to promote new and better ways to collect and disseminate scientific and technical information. Topics mentioned for study and discussion at subsequent meetings included the pros and cons of transferring the NASA/RECON database to the commercial sector, the quality of the database, and developing ways to increase foreign acquisitions. The input systems at AIAA and the STI Facility were described. Also discussed were the proposed RECON II retrieval system, the transmittal of document orders received by the Facility and sent to AIAA, and the handling of multimedia input by the Departments of Defense and Commerce. A second meeting was scheduled for six weeks later to discuss database quality and international foreign input.
Comparison of hospital databases on antibiotic consumption in France, for a single management tool.
Henard, S; Boussat, S; Demoré, B; Clément, S; Lecompte, T; May, T; Rabaud, C
2014-07-01
The surveillance of antibiotic use in hospitals and of data on resistance is an essential measure for antibiotic stewardship. There are 3 national systems in France to collect data on antibiotic use: DREES, ICATB, and ATB RAISIN. We compared these databases and drafted recommendations for the creation of an optimized database of information on antibiotic use, available to all concerned personnel: healthcare authorities, healthcare facilities, and healthcare professionals. We processed and analyzed the 3 databases (2008 data), and surveyed users. The qualitative analysis demonstrated major discrepancies in terms of objectives, healthcare facilities, participation rate, units of consumption, conditions for collection, consolidation, and control of data, and delay before availability of results. The quantitative analysis revealed that the consumption data for a given healthcare facility differed from one database to another, challenging the reliability of data collection. We specified user expectations: to compare consumption and resistance data, to carry out benchmarking, to obtain data on the prescribing habits in healthcare units, or to help understand results. The study results demonstrated the need for a reliable, single, and automated tool to manage data on antibiotic consumption compared with resistance data on several levels (national, regional, healthcare facility, healthcare units), providing rapid local feedback and educational benchmarking. Copyright © 2014 Elsevier Masson SAS. All rights reserved.
EPA Facility Registry System (FRS): NCES
This web feature service contains location and facility identification information from EPA's Facility Registry System (FRS) for the subset of facilities that link to the National Center for Education Statistics (NCES). The primary federal database for collecting and analyzing data related to education in the United States and other Nations, NCES is located in the U.S. Department of Education, within the Institute of Education Sciences. FRS identifies and geospatially locates facilities, sites or places subject to environmental regulations or of environmental interest. Using vigorous verification and data management procedures, FRS integrates facility data from EPA00e2??s national program systems, other federal agencies, and State and tribal master facility records and provides EPA with a centrally managed, single source of comprehensive and authoritative information on facilities. This data set contains the subset of FRS integrated facilities that link to NCES school facilities once the NCES data has been integrated into the FRS database. Additional information on FRS is available at the EPA website http://www.epa.gov/enviro/html/fii/index.html.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Melius, C; Robertson, A; Hullinger, P
2006-10-24
The epidemiological and economic modeling of livestock diseases requires knowing the size, location, and operational type of each livestock facility within the US. At the present time, the only national database of livestock facilities that is available to the general public is the USDA's 2002 Agricultural Census data, published by the National Agricultural Statistics Service, herein referred to as the 'NASS data.' The NASS data provides facility data at the county level for various livestock types (i.e., beef cows, milk cows, cattle on feed, other cattle, total hogs and pigs, sheep and lambs, milk goats, and angora goats). However, themore » number and sizes of facilities for the various livestock types are not independent since some facilities have more than one type of livestock, and some livestock are of more than one type (e.g., 'other cattle' that are being fed for slaughter are also 'cattle on feed'). In addition, any data tabulated by NASS that could identify numbers of animals or other data reported by an individual respondent is suppressed by NASS and coded with a 'D.'. To be useful for epidemiological and economic modeling, the NASS data must be converted into a unique set of facility types (farms having similar operational characteristics). The unique set must not double count facilities or animals. At the same time, it must account for all the animals, including those for which the data has been suppressed. Therefore, several data processing steps are required to work back from the published NASS data to obtain a consistent database for individual livestock operations. This technical report documents data processing steps that were used to convert the NASS data into a national livestock facility database with twenty-eight facility types. The process involves two major steps. The first step defines the rules used to estimate the data that is suppressed within the NASS database. The second step converts the NASS livestock types into the operational facility types used by the epidemiological and economic model. Comparison of the resulting database with an independent survey of farms in central California shows excellent agreement between the numbers of farms for the various facility types. This suggests that the NASS data are well suited for providing a consistent set of county-level information on facility numbers and sizes that can be used in epidemiological and economic models.« less
Moazzeni, Hamidreza; Najafi, Ali; Khani, Marzieh
2017-08-01
Some microRNAs have carcinogenic or tumor suppressive effects in breast cancer, which is the most common cancer in women worldwide. MiR-7 and miR-9 are tumor suppressor microRNAs, which induce apoptosis and inhibit proliferation in breast cancer cells. Moreover, miR-96 and miR-182 are onco-microRNAs that increase proliferation, migration, and tumorigenesis in breast cancer cells. This study aimed to identify the direct target genes of these four microRNAs in the human breast cancer cell lines MCF-7 and MDA-MB-231. Initially, bioinformatics tools were used to identify the target genes that have binding sites for miR-7, MiR-9, MiR-96, and miR-182 and are also associated with breast cancer. Subsequently, the findings of the bioinformatics analysis relating to the effects of these four microRNAs on the 3'-UTR activity of the potential target genes were confirmed using the dual luciferase assay in MCF-7 and MDA-MB-231 cells co-transfected with the vectors containing 3'-UTR segments of the target genes downstream of a luciferase coding gene and each of the microRNAs. Finally, the effects of microRNAs on the endogenous expression of potential target genes were assessed by the overexpression of each of the four microRNAs in MCF-7 and MDA-MB-231 cells. Respectively, three, three, three, and seven genes were found to have binding sites for miR-7, miR-9, miR-96, and miR-182 and were associated with breast cancer. The results of empirical studies including dual luciferase assays and real-time PCR confirmed that miR-7 regulates the expression of BRCA1 and LASP1; MiR-9 regulates the expression of AR; miR-96 regulates the expression of ABCA1; and miR-182 regulates the expression of NBN, TOX3, and LASP1. Taken together, our results suggest that the tumor suppressive effects of miR-7 may be mediated partly by regulating the expression of BRCA1 as a tumor suppressor gene in breast cancer. In addition, this microRNA and miR-182 may have effects on the nodal-positivity and tumor size of breast carcinoma through the regulation of LASP1. The tumor suppressive functions of miR-9 may be mediated partly by suppressing the expression of AR-an oncogene in breast cancer. Moreover, miR-96 may play an oncogenic role in breast cancer by suppressing the apoptosis through the regulation of ABCA1. Copyright © 2017 Elsevier Ltd. All rights reserved.
Data reduction and calibration for LAMOST survey
NASA Astrophysics Data System (ADS)
Luo, Ali; Zhang, Jiannan; Chen, Jianjun; Song, Yihan; Wu, Yue; Bai, Zhongrui; Wang, Fengfei; Du, Bing; Zhang, Haotong
2014-01-01
There are three data pipelines for LAMOST survey. The raw data is reduced to one dimension spectra by the data reduction pipeline(2D pipeline), the extracted spectra are classified and measured by the spectral analysis pipeline(1D pipeline), while stellar parameters are measured by LASP pipeline. (a) The data reduction pipeline. The main tasks of the data reduction pipeline include bias calibration, flat field, spectra extraction, sky subtraction, wavelength calibration, exposure merging and wavelength band connection. (b) The spectra analysis pipeline. This pipeline is designed to classify and identify objects from the extracted spectra and to measure their redshift (or radial velocity). The PCAZ (Glazebrook et al. 1998) method is applied to do the classification and redshift measurement. (c) Stellar parameters LASP. Stellar parameters pipeline (LASP) is to estimate stellar atmospheric parameters, e.g. effective temperature Teff, surface gravity log g, and metallicity [Fe/H], for F, G and K type stars. To effectively determine those fundamental stellar measurements, three steps with different methods are employed. The first step utilizes the line indices to approximately define the effective temperature range of the analyzed star. Secondly, a set of the initial approximate values of the three parameters are given based on template fitting method. Finally, we exploit ULySS (Koleva et al. 2009) to give the final values of parameters through minimizing the χ 2 value between the observed spectrum and a multidimensional grid of model spectra which is generated by an interpolating of ELODIE library. There are two other classification for A type star and M type star. For A type star, standard MK system is employed (Gray et al. 2009) to give each object temperature class and luminosity type. For M type star, they are classified into subclasses by an improved Hammer method, and metallicity of each objects is also given. During the pilot survey, algorithms were improved and the pipelines were tested. The products of LAMOST survey will include extracted and calibrated spectra in FITS format, a catalog of FGK stars with stellar parameters, a catalog of M dwarf with subclass and metallicity, and a catalog of A type star with MK classification. A part of the pilot survey data, including about 319 000 high quality spectra with SNR > 10, a catalog of stellar parameters of FGK stars and another catalog of a subclass of M type stars have been released to the public in August 2012 (Luo et al. 2012). The general survey started from October 2012, and completed the first year survey. The formal data release one (DR1) is being prepared, which will include both pilot survey and first year general survey, and planed to be released under the LAMOST data policy.
LISIRD: Where to go for Solar Irradiance Data
NASA Astrophysics Data System (ADS)
Wilson, A.; Pankratz, C. K.; Lindholm, D. M.; Snow, M.; Knapp, B.; Woodraska, D.; Templeman, B.; Woods, T.; Eparvier, F.; Fontenla, J.; Harder, J.; Bill, M.
2008-12-01
LASP, the Laboratory for Atmospheric and Space Physics, has been providing web access to solar irradiance measurements, reference spectra, composites and model data covering the solar spectrum from .1 to 2400 nm through LISIRD, the LASP Interactive Solar IRradiance Datacenter. No single instrument can measure the solar spectral irradiance from X-rays to the IR, but the ensemble of LASP instruments can. LISIRD uses a single interface to provide easy, logical access to a variety of mission data, merged in time and wavelength. Daily space weather measurements are available, including total solar irradiance (TSI), Lyman Alpha (121 nm), Magnesium II Index (280 nm), He II (30.4 nm), FE XVI (33.5 nm), and the FUV continuum (145 to 165 nm). More recently, LISIRD has recently added the Whole Heliosphere Interval (WHI) Solar Irradiance time series, which provides a quiet sun reference spectra for the period of April 10-16 of 2008. LISIRD also recently added a composite solar spectral irradiance product over the range of 120 to 400 nm for the time period from November 8, 1978 to August 1, 2005. This product, created by Mathew Deland at SSAI, merges data from six different satellites into a single SSI product. And, we are currently adding a time series for daily solar spectral irradiance from 1950 to 2006, created by Judith Lean of the Naval Research Lab. This product adjusts observed irradiance for a given wavelength with parameters that represent known sources of variability at that wavelength. LISIRD remains committed to improving data access in a variety of ways. We are planning and developing a means for the broader community of scientists to easily determine data availability for a particular date range without having to know mission or instrument details. Improved data subsetting will allow users to request only the time range or spectra that users need, making data management generally easier. We expect to continue to enhance our data offerings. Future vision for LISIRD also includes integration of improved data visualization and analysis tools. We welcome contributions from solar science community members who wish to share data and tools they have developed. We also expect to integrate LISIRD with the Virtual Solar Observatory (VSO) and other relevant Virtual Observatories (VOs) for a more integrated and complete user experience. We are actively seeking input and feedback to improve LISIRD from interested users of this data. Towards this end we have provided a survey at our website and to AGU attendees. Those who use LISIRD and provide feedback will have the opportunity to help steer LISIRD development. Let us know what you would like to see and we will try to make it happen!
EPA Facility Registry Service (FRS): TRI
This web feature service contains location and facility identification information from EPA's Facility Registry Service (FRS) for the subset of facilities that link to the Toxic Release Inventory (TRI) System. TRI is a publicly available EPA database reported annually by certain covered industry groups, as well as federal facilities. It contains information about more than 650 toxic chemicals that are being used, manufactured, treated, transported, or released into the environment, and includes information about waste management and pollution prevention activities. FRS identifies and geospatially locates facilities, sites or places subject to environmental regulations or of environmental interest. Using vigorous verification and data management procedures, FRS integrates facility data from EPA's national program systems, other federal agencies, and State and tribal master facility records and provides EPA with a centrally managed, single source of comprehensive and authoritative information on facilities. This data set contains the subset of FRS integrated facilities that link to TRI facilities once the TRI data has been integrated into the FRS database. Additional information on FRS is available at the EPA website https://www.epa.gov/enviro/facility-registry-service-frs.
47 CFR 69.120 - Line information database.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 47 Telecommunication 3 2011-10-01 2011-10-01 false Line information database. 69.120 Section 69...) ACCESS CHARGES Computation of Charges § 69.120 Line information database. (a) A charge that is expressed... from a local exchange carrier database to recover the costs of: (1) The transmission facilities between...
47 CFR 69.120 - Line information database.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 47 Telecommunication 3 2013-10-01 2013-10-01 false Line information database. 69.120 Section 69...) ACCESS CHARGES Computation of Charges § 69.120 Line information database. (a) A charge that is expressed... from a local exchange carrier database to recover the costs of: (1) The transmission facilities between...
47 CFR 69.120 - Line information database.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 47 Telecommunication 3 2014-10-01 2014-10-01 false Line information database. 69.120 Section 69...) ACCESS CHARGES Computation of Charges § 69.120 Line information database. (a) A charge that is expressed... from a local exchange carrier database to recover the costs of: (1) The transmission facilities between...
47 CFR 69.120 - Line information database.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 47 Telecommunication 3 2010-10-01 2010-10-01 false Line information database. 69.120 Section 69...) ACCESS CHARGES Computation of Charges § 69.120 Line information database. (a) A charge that is expressed... from a local exchange carrier database to recover the costs of: (1) The transmission facilities between...
47 CFR 69.120 - Line information database.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 47 Telecommunication 3 2012-10-01 2012-10-01 false Line information database. 69.120 Section 69...) ACCESS CHARGES Computation of Charges § 69.120 Line information database. (a) A charge that is expressed... from a local exchange carrier database to recover the costs of: (1) The transmission facilities between...
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
2002-12-18
KENNEDY SPACE CENTER, FLA. -- Workers prepare a Pegasus XL Expendable Launch Vehicle for detachment from the underside of an Orbital Sciences L-1011 aircraft. The aircraft, with the launch vehicle nestled beneath, arrived at the Cape Canaveral Air Force Station Skid Strip on Dec. 17. The Pegasus XL will undergo three flight simulations prior to its scheduled launch in late January 2003. It will carry NASA's Solar Radiation and Climate Experiment (SORCE) spacecraft into orbit. Built by Orbital Sciences Space Systems Group, SORCE will study and measure solar irradiance as a source of energy in the Earth's atmosphere with instruments built by the University of Colorado's Laboratory for Atmospheric and Space Physics (LASP).
2002-12-18
KENNEDY SPACE CENTER, FLA. -- Workers prepare to remove a Pegasus XL Expendable Launch Vehicle from the underside of an Orbital Sciences L-1011 aircraft. The aircraft, with the launch vehicle attached, arrived at the Cape Canaveral Air Force Station Skid Strip on Dec. 17. The Pegasus XL will undergo three flight simulations prior to its scheduled launch in late January 2003. It will carry NASA's Solar Radiation and Climate Experiment (SORCE) spacecraft into orbit. Built by Orbital Sciences Space Systems Group, SORCE will study and measure solar irradiance as a source of energy in the Earth's atmosphere with instruments built by the University of Colorado's Laboratory for Atmospheric and Space Physics (LASP).
2002-12-18
KENNEDY SPACE CENTER, FLA. -- A Pegasus XL Expendable Launch Vehicle is moments away from being removed from the underside of an Orbital Sciences L-1011 aircraft. The aircraft, with the launch vehicle attached, arrived at the Cape Canaveral Air Force Station Skid Strip on Dec. 17. The Pegasus XL will undergo three flight simulations prior to its scheduled launch in late January 2003. It will carry NASA's Solar Radiation and Climate Experiment (SORCE) spacecraft into orbit. Built by Orbital Sciences Space Systems Group, SORCE will study and measure solar irradiance as a source of energy in the Earth's atmosphere with instruments built by the University of Colorado's Laboratory for Atmospheric and Space Physics (LASP).
2002-12-18
KENNEDY SPACE CENTER, FLA. -- Workers begin the process to remove a Pegasus XL Expendable Launch Vehicle from the underside of an Orbital Sciences L-1011 aircraft. The aircraft, with the launch vehicle attached, arrived at the Cape Canaveral Air Force Station Skid Strip on Dec. 17. The Pegasus XL will undergo three flight simulations prior to its scheduled launch in late January 2003. It will carry NASA's Solar Radiation and Climate Experiment (SORCE) spacecraft into orbit. Built by Orbital Sciences Space Systems Group, SORCE will study and measure solar irradiance as a source of energy in the Earth's atmosphere with instruments built by the University of Colorado's Laboratory for Atmospheric and Space Physics (LASP).
JetWeb: A WWW interface and database for Monte Carlo tuning and validation
NASA Astrophysics Data System (ADS)
Butterworth, J. M.; Butterworth, S.
2003-06-01
A World Wide Web interface to a Monte Carlo tuning facility is described. The aim of the package is to allow rapid and reproducible comparisons to be made between detailed measurements at high-energy physics colliders and general physics simulation packages. The package includes a relational database, a Java servlet query and display facility, and clean interfaces to simulation packages and their parameters.
ERIC Educational Resources Information Center
Mancall, Jacqueline C.; Deskins, Dreama
This report assesses the impact of instruction in online bibliographic database searching on high school students' use of library materials and facilities in three Delaware secondary schools (one public, one parochial, and one private) during the spring of 1984. Most students involved in the analysis were given a brief explanation of online…
Baker, J
1996-01-01
The purpose of this study was to identify patterns of admission, discharge, and readmission between hospital and long-term care facility among a group of Florida long-term care facility residents with pressure ulcers whose care was paid for by Medicaid. A patient-specific, longitudinal claims history database was constructed from data provided by the Florida Department of Health and Rehabilitative Services. This database was used to determine and analyze hospital admissions for pressure ulcer care among Medicaid recipients cared for in a long-term care facility. Analysis of the data determined that more than half of the Medicaid-covered long-term care facility residents who formed the target study group (54.57%) had multiple hospital admissions associated with pressure ulcers. Pressure ulcer hospital admissions amounted to a program cost of $9.9 million.
Disaster Debris Recovery Database - Recovery
The US EPA Region 5 Disaster Debris Recovery Database includes public datasets of over 6,000 composting facilities, demolition contractors, transfer stations, landfills and recycling facilities for construction and demolition materials, electronics, household hazardous waste, metals, tires, and vehicles in the states of Illinois, Indiana, Iowa, Kentucky, Michigan, Minnesota, Missouri, North Dakota, Ohio, Pennsylvania, South Dakota, West Virginia and Wisconsin.In this update, facilities in the 7 states that border the EPA Region 5 states were added to assist interstate disaster debris management. Also, the datasets for composters, construction and demolition recyclers, demolition contractors, and metals recyclers were verified and source information added for each record using these sources: AGC, Biocycle, BMRA, CDRA, ISRI, NDA, USCC, FEMA Debris Removal Contractor Registry, EPA Facility Registry System, and State and local listings.
Disaster Debris Recovery Database - Landfills
The US EPA Region 5 Disaster Debris Recovery Database includes public datasets of over 6,000 composting facilities, demolition contractors, transfer stations, landfills and recycling facilities for construction and demolition materials, electronics, household hazardous waste, metals, tires, and vehicles in the states of Illinois, Indiana, Iowa, Kentucky, Michigan, Minnesota, Missouri, North Dakota, Ohio, Pennsylvania, South Dakota, West Virginia and Wisconsin.In this update, facilities in the 7 states that border the EPA Region 5 states were added to assist interstate disaster debris management. Also, the datasets for composters, construction and demolition recyclers, demolition contractors, and metals recyclers were verified and source information added for each record using these sources: AGC, Biocycle, BMRA, CDRA, ISRI, NDA, USCC, FEMA Debris Removal Contractor Registry, EPA Facility Registry System, and State and local listings.
Facility Registry Service (FRS)
This is a centrally managed database that identifies facilities either subject to environmental regulations or of environmental interest, providing an integrated source of air, water, and waste environmental data.
DOT National Transportation Integrated Search
2012-03-01
This project initiated the development of a computerized database of ITS facilities, including conduits, junction : boxes, cameras, connections, etc. The current system consists of a database of conduit sections of various lengths. : Over the length ...
National Transportation Atlas Databases : 2014
DOT National Transportation Integrated Search
2014-01-01
The National Transportation Atlas Databases 2014 : (NTAD2014) is a set of nationwide geographic datasets of : transportation facilities, transportation networks, associated : infrastructure, and other political and administrative entities. : These da...
National Transportation Atlas Databases : 2015
DOT National Transportation Integrated Search
2015-01-01
The National Transportation Atlas Databases 2015 : (NTAD2015) is a set of nationwide geographic datasets of : transportation facilities, transportation networks, associated : infrastructure, and other political and administrative entities. : These da...
National Transportation Atlas Databases : 2013
DOT National Transportation Integrated Search
2013-01-01
The National Transportation Atlas Databases 2013 (NTAD2013) is a set of nationwide geographic datasets of transportation facilities, transportation networks, associated infrastructure, and other political and administrative entities. These datasets i...
SNaX: A Database of Supernova X-Ray Light Curves
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ross, Mathias; Dwarkadas, Vikram V., E-mail: Mathias_Ross@msn.com, E-mail: vikram@oddjob.uchicago.edu
We present the Supernova X-ray Database (SNaX), a compilation of the X-ray data from young supernovae (SNe). The database includes the X-ray fluxes and luminosities of young SNe, from days to years after outburst. The original goal and intent of this study was to present a database of Type IIn SNe (SNe IIn), which we have accomplished. Our ongoing goal is to expand the database to include all SNe for which published data are available. The database interface allows one to search for SNe using various criteria, plot all or selected data points, and download both the data and themore » plot. The plotting facility allows for significant customization. There is also a facility for the user to submit data that can be directly incorporated into the database. We include an option to fit the decay of any given SN light curve with a power-law. The database includes a conversion of most data points to a common 0.3–8 keV band so that SN light curves may be directly compared with each other. A mailing list has been set up to disseminate information about the database. We outline the structure and function of the database, describe its various features, and outline the plans for future expansion.« less
EPA Facility Registry Service (FRS): ICIS
This web feature service contains location and facility identification information from EPA's Facility Registry Service (FRS) for the subset of facilities that link to the Integrated Compliance Information System (ICIS). When complete, ICIS will provide a database that will contain integrated enforcement and compliance information across most of EPA's programs. The vision for ICIS is to replace EPA's independent databases that contain enforcement data with a single repository for that information. Currently, ICIS contains all Federal Administrative and Judicial enforcement actions and a subset of the Permit Compliance System (PCS), which supports the National Pollutant Discharge Elimination System (NPDES). ICIS exchanges non-sensitive enforcement/compliance activities, non-sensitive formal enforcement actions and NPDES information with FRS. This web feature service contains the enforcement/compliance activities and formal enforcement action related facilities; the NPDES facilities are contained in the PCS_NPDES web feature service. FRS identifies and geospatially locates facilities, sites or places subject to environmental regulations or of environmental interest. Using vigorous verification and data management procedures, FRS integrates facility data from EPA's national program systems, other federal agencies, and State and tribal master facility records and provides EPA with a centrally managed, single source of comprehensive and authoritative information on f
Code of Federal Regulations, 2010 CFR
2010-07-01
... POLICY AND IMPLEMENTATION OF RECIPROCITY OF FACILITIES National Policy on Reciprocity of Use and... value added to the process of co-use of facilities by development of electronic data retrieval across government. As this review continues, agencies creating or modifying facilities databases will do so in a...
Does High School Facility Quality Affect Student Achievement? A Two-Level Hierarchical Linear Model
ERIC Educational Resources Information Center
Bowers, Alex J.; Urick, Angela
2011-01-01
The purpose of this study is to isolate the independent effects of high school facility quality on student achievement using a large, nationally representative U.S. database of student achievement and school facility quality. Prior research on linking school facility quality to student achievement has been mixed. Studies that relate overall…
Transterm—extended search facilities and improved integration with other databases
Jacobs, Grant H.; Stockwell, Peter A.; Tate, Warren P.; Brown, Chris M.
2006-01-01
Transterm has now been publicly available for >10 years. Major changes have been made since its last description in this database issue in 2002. The current database provides data for key regions of mRNA sequences, a curated database of mRNA motifs and tools to allow users to investigate their own motifs or mRNA sequences. The key mRNA regions database is derived computationally from Genbank. It contains 3′ and 5′ flanking regions, the initiation and termination signal context and coding sequence for annotated CDS features from Genbank and RefSeq. The database is non-redundant, enabling summary files and statistics to be prepared for each species. Advances include providing extended search facilities, the database may now be searched by BLAST in addition to regular expressions (patterns) allowing users to search for motifs such as known miRNA sequences, and the inclusion of RefSeq data. The database contains >40 motifs or structural patterns important for translational control. In this release, patterns from UTRsite and Rfam are also incorporated with cross-referencing. Users may search their sequence data with Transterm or user-defined patterns. The system is accessible at . PMID:16381889
NASA Technical Reports Server (NTRS)
Steele, Jimmy; Smith, Robert E.
1991-01-01
The ability to identify contaminants associated with experiments and facilities is directly related to the safety of the Space Station. A means of identifying these contaminants has been developed through this contracting effort. The delivered system provides a listing of the materials and/or chemicals associated with each facility, information as to the contaminant's physical state, a list of the quantity and/or volume of each suspected contaminant, a database of the toxicological hazards associated with each contaminant, a recommended means of rapid identification of the contaminants under operational conditions, a method of identifying possible failure modes and effects analysis associated with each facility, and a fault tree-type analysis that will provide a means of identifying potential hazardous conditions related to future planned missions.
Evaluation of the national tuberculosis surveillance program in Haiti
Salyer, S. J.; Fitter, D. L.; Milo, R.; Blanton, C.; Ho, J. L.; Geffrard, H.; Morose, W.; Marston, B. J.
2015-01-01
OBJECTIVE To assess the quality of tuberculosis (TB) surveillance in Haiti, including whether underreporting from facilities to the national level contributes to low national case registration. METHODS We collected 2010 and 2012 TB case totals, reviewed laboratory registries, and abstracted individual TB case reports from 32 of 263 anti-tuberculosis treatment facilities randomly selected after stratification/weighting toward higher-volume facilities. We compared site results to national databases maintained by a non-governmental organization partner (International Child Care [ICC]) for 2010 and 2012, and the National TB Program (Programme National de Lutte contre la Tuberculose, PNLT) for 2012 only. RESULTS Case registries were available at 30/32 facilities for 2010 and all 32 for 2012. Totals of 3711 (2010) and 4143 (2012) cases were reported at the facilities. Case totals per site were higher in site registries than in the national databases by 361 (9.7%) (ICC 2010), 28 (0.8%) (ICC 2012), and 31 (0.8%) cases (PNLT 2012). Of abstracted individual cases, respectively 11.8% and 6.8% were not recorded in national databases for 2010 (n = 323) and 2012 (n = 351). CONCLUSIONS The evaluation demonstrated an improvement in reporting registered TB cases to the PNLT in Haiti between 2010 and 2012. Further improvement in case notification will require enhanced case detection and diagnosis. PMID:26260822
Facilities Management via Computer: Information at Your Fingertips.
ERIC Educational Resources Information Center
Hensey, Susan
1996-01-01
Computer-aided facilities management is a software program consisting of a relational database of facility information--such as occupancy, usage, student counts, etc.--attached to or merged with computerized floor plans. This program can integrate data with drawings, thereby allowing the development of "what if" scenarios. (MLF)
2002-12-18
KENNEDY SPACE CENTER, FLA. -- Workers supervise the placement of a transporter below a Pegasus XL Expendable Launch Vehicle before its detachment from the underside of an Orbital Sciences L-1011 aircraft. The aircraft, with the launch vehicle nestled beneath, arrived at the Cape Canaveral Air Force Station Skid Strip on Dec. 17. The Pegasus XL will undergo three flight simulations prior to its scheduled launch in late January 2003. It will carry NASA's Solar Radiation and Climate Experiment (SORCE) spacecraft into orbit. Built by Orbital Sciences Space Systems Group, SORCE will study and measure solar irradiance as a source of energy in the Earth's atmosphere with instruments built by the University of Colorado's Laboratory for Atmospheric and Space Physics (LASP).
2002-12-18
KENNEDY SPACE CENTER, FLA. -- Workers complete the final steps to detach a Pegasus XL Expendable Launch Vehicle from the underside of an Orbital Sciences L-1011 aircraft. The aircraft, with the launch vehicle nestled beneath, arrived at the Cape Canaveral Air Force Station Skid Strip on Dec. 17. The Pegasus XL will undergo three flight simulations prior to its scheduled launch in late January 2003. It will carry NASA's Solar Radiation and Climate Experiment (SORCE) spacecraft into orbit. Built by Orbital Sciences Space Systems Group, SORCE will study and measure solar irradiance as a source of energy in the Earth's atmosphere with instruments built by the University of Colorado's Laboratory for Atmospheric and Space Physics (LASP).
2002-12-18
KENNEDY SPACE CENTER, FLA. -- A transporter is repositioned below a Pegasus XL Expendable Launch Vehicle before it is detached from the underside of an Orbital Sciences L-1011 aircraft. The aircraft, with the launch vehicle nestled beneath, arrived at the Cape Canaveral Air Force Station Skid Strip on Dec. 17. The Pegasus XL will undergo three flight simulations prior to its scheduled launch in late January 2003. It will carry NASA's Solar Radiation and Climate Experiment (SORCE) spacecraft into orbit. Built by Orbital Sciences Space Systems Group, SORCE will study and measure solar irradiance as a source of energy in the Earth's atmosphere with instruments built by the University of Colorado's Laboratory for Atmospheric and Space Physics (LASP).
2002-12-18
KENNEDY SPACE CENTER, FLA. -- A transporter is positioned below a Pegasus XL Expendable Launch Vehicle before its detachment from the underside of an Orbital Sciences L-1011 aircraft. The aircraft, with the launch vehicle nestled beneath, arrived at the Cape Canaveral Air Force Station Skid Strip on Dec. 17. The Pegasus XL will undergo three flight simulations prior to its scheduled launch in late January 2003. It will carry NASA's Solar Radiation and Climate Experiment (SORCE) spacecraft into orbit. Built by Orbital Sciences Space Systems Group, SORCE will study and measure solar irradiance as a source of energy in the Earth's atmosphere with instruments built by the University of Colorado's Laboratory for Atmospheric and Space Physics (LASP).
A SLAM II simulation model for analyzing space station mission processing requirements
NASA Technical Reports Server (NTRS)
Linton, D. G.
1985-01-01
Space station mission processing is modeled via the SLAM 2 simulation language on an IBM 4381 mainframe and an IBM PC microcomputer with 620K RAM, two double-sided disk drives and an 8087 coprocessor chip. Using a time phased mission (payload) schedule and parameters associated with the mission, orbiter (space shuttle) and ground facility databases, estimates for ground facility utilization are computed. Simulation output associated with the science and applications database is used to assess alternative mission schedules.
The INFN-CNAF Tier-1 GEMSS Mass Storage System and database facility activity
NASA Astrophysics Data System (ADS)
Ricci, Pier Paolo; Cavalli, Alessandro; Dell'Agnello, Luca; Favaro, Matteo; Gregori, Daniele; Prosperini, Andrea; Pezzi, Michele; Sapunenko, Vladimir; Zizzi, Giovanni; Vagnoni, Vincenzo
2015-05-01
The consolidation of Mass Storage services at the INFN-CNAF Tier1 Storage department that has occurred during the last 5 years, resulted in a reliable, high performance and moderately easy-to-manage facility that provides data access, archive, backup and database services to several different use cases. At present, the GEMSS Mass Storage System, developed and installed at CNAF and based upon an integration between the IBM GPFS parallel filesystem and the Tivoli Storage Manager (TSM) tape management software, is one of the largest hierarchical storage sites in Europe. It provides storage resources for about 12% of LHC data, as well as for data of other non-LHC experiments. Files are accessed using standard SRM Grid services provided by the Storage Resource Manager (StoRM), also developed at CNAF. Data access is also provided by XRootD and HTTP/WebDaV endpoints. Besides these services, an Oracle database facility is in production characterized by an effective level of parallelism, redundancy and availability. This facility is running databases for storing and accessing relational data objects and for providing database services to the currently active use cases. It takes advantage of several Oracle technologies, like Real Application Cluster (RAC), Automatic Storage Manager (ASM) and Enterprise Manager centralized management tools, together with other technologies for performance optimization, ease of management and downtime reduction. The aim of the present paper is to illustrate the state-of-the-art of the INFN-CNAF Tier1 Storage department infrastructures and software services, and to give a brief outlook to forthcoming projects. A description of the administrative, monitoring and problem-tracking tools that play a primary role in managing the whole storage framework is also given.
Content Is King: Databases Preserve the Collective Information of Science.
Yates, John R
2018-04-01
Databases store sequence information experimentally gathered to create resources that further science. In the last 20 years databases have become critical components of fields like proteomics where they provide the basis for large-scale and high-throughput proteomic informatics. Amos Bairoch, winner of the Association of Biomolecular Resource Facilities Frederick Sanger Award, has created some of the important databases proteomic research depends upon for accurate interpretation of data.
Honoré, Paul; Granjeaud, Samuel; Tagett, Rebecca; Deraco, Stéphane; Beaudoing, Emmanuel; Rougemont, Jacques; Debono, Stéphane; Hingamp, Pascal
2006-09-20
High throughput gene expression profiling (GEP) is becoming a routine technique in life science laboratories. With experimental designs that repeatedly span thousands of genes and hundreds of samples, relying on a dedicated database infrastructure is no longer an option.GEP technology is a fast moving target, with new approaches constantly broadening the field diversity. This technology heterogeneity, compounded by the informatics complexity of GEP databases, means that software developments have so far focused on mainstream techniques, leaving less typical yet established techniques such as Nylon microarrays at best partially supported. MAF (MicroArray Facility) is the laboratory database system we have developed for managing the design, production and hybridization of spotted microarrays. Although it can support the widely used glass microarrays and oligo-chips, MAF was designed with the specific idiosyncrasies of Nylon based microarrays in mind. Notably single channel radioactive probes, microarray stripping and reuse, vector control hybridizations and spike-in controls are all natively supported by the software suite. MicroArray Facility is MIAME supportive and dynamically provides feedback on missing annotations to help users estimate effective MIAME compliance. Genomic data such as clone identifiers and gene symbols are also directly annotated by MAF software using standard public resources. The MAGE-ML data format is implemented for full data export. Journalized database operations (audit tracking), data anonymization, material traceability and user/project level confidentiality policies are also managed by MAF. MicroArray Facility is a complete data management system for microarray producers and end-users. Particular care has been devoted to adequately model Nylon based microarrays. The MAF system, developed and implemented in both private and academic environments, has proved a robust solution for shared facilities and industry service providers alike.
Honoré, Paul; Granjeaud, Samuel; Tagett, Rebecca; Deraco, Stéphane; Beaudoing, Emmanuel; Rougemont, Jacques; Debono, Stéphane; Hingamp, Pascal
2006-01-01
Background High throughput gene expression profiling (GEP) is becoming a routine technique in life science laboratories. With experimental designs that repeatedly span thousands of genes and hundreds of samples, relying on a dedicated database infrastructure is no longer an option. GEP technology is a fast moving target, with new approaches constantly broadening the field diversity. This technology heterogeneity, compounded by the informatics complexity of GEP databases, means that software developments have so far focused on mainstream techniques, leaving less typical yet established techniques such as Nylon microarrays at best partially supported. Results MAF (MicroArray Facility) is the laboratory database system we have developed for managing the design, production and hybridization of spotted microarrays. Although it can support the widely used glass microarrays and oligo-chips, MAF was designed with the specific idiosyncrasies of Nylon based microarrays in mind. Notably single channel radioactive probes, microarray stripping and reuse, vector control hybridizations and spike-in controls are all natively supported by the software suite. MicroArray Facility is MIAME supportive and dynamically provides feedback on missing annotations to help users estimate effective MIAME compliance. Genomic data such as clone identifiers and gene symbols are also directly annotated by MAF software using standard public resources. The MAGE-ML data format is implemented for full data export. Journalized database operations (audit tracking), data anonymization, material traceability and user/project level confidentiality policies are also managed by MAF. Conclusion MicroArray Facility is a complete data management system for microarray producers and end-users. Particular care has been devoted to adequately model Nylon based microarrays. The MAF system, developed and implemented in both private and academic environments, has proved a robust solution for shared facilities and industry service providers alike. PMID:16987406
Environmental Factor(tm) system: RCRA hazardous waste handler information (on cd-rom). Database
DOE Office of Scientific and Technical Information (OSTI.GOV)
NONE
1996-04-01
Environmental Factor(tm) RCRA Hazardous Waste Handler Information on CD-ROM unleashes the invaluable information found in two key EPA data sources on hazardous waste handlers and offers cradle-to-grave waste tracking. It`s easy to search and display: (1) Permit status, design capacity and compliance history for facilities found in the EPA Resource Conservation and Recovery Information System (RCRIS) program tracking database; (2) Detailed information on hazardous wastes generation, management and minimization by companies who are large quantity generators, and (3) Data on the waste management practices of treatment, storage and disposal (TSD) facilities from the EPA Biennial Reporting System which is collectedmore » every other year. Environmental Factor`s powerful database retrieval system lets you: (1) Search for RCRA facilities by permit type, SIC code, waste codes, corrective action or violation information, TSD status, generator and transporter status and more; (2) View compliance information - dates of evaluation, violation, enforcement and corrective action; (3) Lookup facilities by waste processing categories of marketing, transporting, processing and energy recovery; (4) Use owner/operator information and names, titles and telephone numbers of project managers for prospecting; and (5) Browse detailed data on TSD facility and large quantity generators` activities such as onsite waste treatment, disposal, or recycling, offsite waste received, and waste generation and management. The product contains databases, search and retrieval software on two CD-ROMs, an installation diskette and User`s Guide. Environmental Factor has online context-sensitive help from any screen and a printed User`s Guide describing installation and step-by-step procedures for searching, retrieving and exporting. Hotline support is also available for no additional charge.« less
Freight Transportation Energy Use : Volume 3. Freight Network and Operations Database.
DOT National Transportation Integrated Search
1979-07-01
The data sources, procedures, and assumptions used to generate the TSC national freight network and operations database are documented. National rail, highway, waterway, and pipeline networks are presented, and estimates of facility capacity, travel ...
47 CFR 90.1319 - Policies governing the use of the 3650-3700 MHz band.
Code of Federal Regulations, 2010 CFR
2010-10-01
... potential for interference and make the most effective use of the authorized facilities. A database... should examine this database before seeking station authorization, and make every effort to ensure that...
This page is the starting point for EZ Query. This page describes how to select key data elements from EPA's Facility Information Database and Geospatial Reference Database to build a tabular report or a Comma Separated Value (CSV) files for downloading.
Evaluating and improving pressure ulcer care: the VA experience with administrative data.
Berlowitz, D R; Halpern, J
1997-08-01
A number of state initiatives are using databases originally developed for nursing home reimbursements to assess the quality of care. Since 1991 the Department of Veterans Affairs (VA; Washington, DC) has been using a long term care administrative database to calculate facility-specific rates of pressure ulcer development. This information is disseminated to all 140 long term care facilities as part of a quality assessment and improvement program. Assessments are performed on all long term care residents on April 1 and October 1, as well as at the time of admission or transfer to a long term care unit. Approximately 18,000 long term care residents are evaluated in each six-month period; the VA rate of pressure ulcer development is approximately 3.5%. Reports of the rates of pressure ulcer development are then disseminated to all facilities, generally within two months of the assessment date. The VA's more than five years' experience in using administrative data to assess outcomes for long term care highlights several important issues that should be considered when using outcome measures based on administrative data. These include the importance of carefully selecting the outcome measure, the need to consider the structure of the database, the role of case-mix adjustment, strategies for reporting rates to small facilities, and methods for information dissemination. Attention to these issues will help ensure that results from administrative databases lead to improvements in the quality of care.
New data sources and derived products for the SRER digital spatial database
Craig Wissler; Deborah Angell
2003-01-01
The Santa Rita Experimental Range (SRER) digital database was developed to automate and preserve ecological data and increase their accessibility. The digital data holdings include a spatial database that is used to integrate ecological data in a known reference system and to support spatial analyses. Recently, the Advanced Resource Technology (ART) facility has added...
A spatial national health facility database for public health sector planning in Kenya in 2008.
Noor, Abdisalan M; Alegana, Victor A; Gething, Peter W; Snow, Robert W
2009-03-06
Efforts to tackle the enormous burden of ill-health in low-income countries are hampered by weak health information infrastructures that do not support appropriate planning and resource allocation. For health information systems to function well, a reliable inventory of health service providers is critical. The spatial referencing of service providers to allow their representation in a geographic information system is vital if the full planning potential of such data is to be realized. A disparate series of contemporary lists of health service providers were used to update a public health facility database of Kenya last compiled in 2003. These new lists were derived primarily through the national distribution of antimalarial and antiretroviral commodities since 2006. A combination of methods, including global positioning systems, was used to map service providers. These spatially-referenced data were combined with high-resolution population maps to analyze disparity in geographic access to public health care. The updated 2008 database contained 5,334 public health facilities (67% ministry of health; 28% mission and nongovernmental organizations; 2% local authorities; and 3% employers and other ministries). This represented an overall increase of 1,862 facilities compared to 2003. Most of the additional facilities belonged to the ministry of health (79%) and the majority were dispensaries (91%). 93% of the health facilities were spatially referenced, 38% using global positioning systems compared to 21% in 2003. 89% of the population was within 5 km Euclidean distance to a public health facility in 2008 compared to 71% in 2003. Over 80% of the population outside 5 km of public health service providers was in the sparsely settled pastoralist areas of the country. We have shown that, with concerted effort, a relatively complete inventory of mapped health services is possible with enormous potential for improving planning. Expansion in public health care in Kenya has resulted in significant increases in geographic access although several areas of the country need further improvements. This information is key to future planning and with this paper we have released the digital spatial database in the public domain to assist the Kenyan Government and its partners in the health sector.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Erickson, T.A.
1998-11-01
The objectives of this task are to: Develop a model (paper) to estimate the cost and waste generation of cleanup within the Environmental Management (EM) complex; Identify technologies applicable to decontamination and decommissioning (D and D) operations within the EM complex; Develop a database of facility information as linked to project baseline summaries (PBSs). The above objectives are carried out through the following four subtasks: Subtask 1--D and D Model Development, Subtask 2--Technology List; Subtask 3--Facility Database, and Subtask 4--Incorporation into a User Model.
The Get Going to Mars campaign: an outreach experiment in art, literacy, and science
NASA Astrophysics Data System (ADS)
Renfrow, S.; Mason, T.; Christofferson, R.
2013-12-01
The 6-month Going to Mars campaign brought crowdsourcing to the next NASA Mars mission: a student art contest flooded us in the colorful imagination of children; a haiku contest gave us poetry about dunes and ice caps, love, humor, and our place in the universe; and a send-your-name activity connected MAVEN with tens of thousands of people. In this discussion, we'll dive into the statistics (1+ million page views, 15,000+ message submissions, 375+ art entries), the individual winners from small-town USA and across the globe, and the dirt and grit that made the Going to Mars campaign come alive. View the archived site at http://lasp.colorado.edu/home/maven/goingtomars.
Olympic Information in the SPORT Database.
ERIC Educational Resources Information Center
Belna, Alison M.; And Others
1984-01-01
Profiles the SPORT database, produced by Sport Information Resource Centre, Ottawa, Ontario, which provides extensive coverage of individual sports including practice, training and equipment, recreation, sports medicine, physical education, sport facilities, and international sport history. Olympic coverage in SPORT, sports sciences, online…
Data structures and organisation: Special problems in scientific applications
NASA Astrophysics Data System (ADS)
Read, Brian J.
1989-12-01
In this paper we discuss and offer answers to the following questions: What, really, are the benifits of databases in physics? Are scientific databases essentially different from conventional ones? What are the drawbacks of a commercial database management system for use with scientific data? Do they outweigh the advantages? Do databases systems have adequate graphics facilities, or is a separate graphics package necessary? SQL as a standard language has deficiencies, but what are they for scientific data in particular? Indeed, is the relational model appropriate anyway? Or, should we turn to object oriented databases?
Weile, Jesper; Nielsen, Klaus; Primdahl, Stine C; Frederiksen, Christian A; Laursen, Christian B; Sloth, Erik; Mølgaard, Ole; Knudsen, Lars; Kirkegaard, Hans
2018-03-27
Trauma is a leading cause of death among adults aged < 44 years, and optimal care is a challenge. Evidence supports the centralization of trauma facilities and the use multidisciplinary trauma teams. Because knowledge is sparse on the existing distribution of trauma facilities and the organisation of trauma care in Denmark, the aim of this study was to identify all Danish facilities that care for traumatized patients and to investigate the diversity in organization of trauma management. We conducted a systematic observational cross-sectional study. First, all hospitals in Denmark were identified via online services and clarifying phone calls to each facility. Second, all trauma care manuals on all facilities that receive traumatized patients were gathered. Third, anesthesiologists and orthopedic surgeons on call at all trauma facilities were contacted via telephone for structured interviews. A total of 22 facilities in Denmark were found to receive traumatized patients. All facilities used a trauma care manual and all had a multidisciplinary trauma team. The study found three different trauma team activation criteria and nine different compositions of teams who participate in trauma care. Training was heterogeneous and, beyond the major trauma centers, databases were only maintained in a few facilities. The study established an inventory of the existing Danish facilities that receive traumatized patients. The trauma team activation criteria and the trauma teams were heterogeneous in both size and composition. A national database for traumatized patients, research on nationwide trauma team activation criteria, and team composition guidelines are all called for.
ERIC Educational Resources Information Center
May, Abigail
1998-01-01
Offers some key business principles with the hope of helping educational facilities managers improve their operations. Looks at customer service, disparate databases, technological concerns, the mission of facility management, how to improve the bottom line, staffing ideas, future planning, and management suggestions. Lists seven habits of…
A novel image database analysis system maintenance of transportation facility.
DOT National Transportation Integrated Search
2009-01-01
The current project was funded by MIOH-UTC in the Spring of 2008 to investigate efficient : maintenance methods for transportation facilities. To achieve the objectives of the project, the : PIs undertook the research of various technologies of image...
A Functional Approach to Hyperspectral Image Analysis in the Cloud
NASA Astrophysics Data System (ADS)
Wilson, A.; Lindholm, D. M.; Coddington, O.; Pilewskie, P.
2017-12-01
Hyperspectral image volumes are very large. A hyperspectral image analysis (HIA) may use 100TB of data, a huge barrier to their use. Hylatis is a new NASA project to create a toolset for HIA. Through web notebook and cloud technology, Hylatis will provide a more interactive experience for HIA by defining and implementing concepts and operations for HIA, identified and vetted by subject matter experts, and callable within a general purpose language, particularly Python. Hylatis leverages LaTiS, a data access framework developed at LASP. With an OPeNDAP compliant interface plus additional server side capabilities, the LaTiS API provides a uniform interface to virtually any data source, and has been applied to various storage systems, including: file systems, databases, remote servers, and in various domains including: space science, systems administration and stock quotes. In the LaTiS architecture, data `adapters' read data into a data model, where server-side computations occur. Data `writers' write data from the data model into the desired format. The Hylatis difference is the data model. In LaTiS, data are represented as mathematical functions of independent and dependent variables. Domain semantics are not present at this level, but are instead present in higher software layers. The benefit of a domain agnostic, mathematical representation is having the power of math, particularly functional algebra, unconstrained by domain semantics. This agnosticism supports reusable server side functionality applicable in any domain, such as statistical, filtering, or projection operations. Algorithms to aggregate or fuse data can be simpler because domain semantics are separated from the math. Hylatis will map the functional model onto the Spark relational interface, thereby adding a functional interface to that big data engine.This presentation will discuss Hylatis goals, strategies, and current state.
Supporting NASA Facilities Through GIS
NASA Technical Reports Server (NTRS)
Ingham, Mary E.
2000-01-01
The NASA GIS Team supports NASA facilities and partners in the analysis of spatial data. Geographic Information System (G[S) is an integration of computer hardware, software, and personnel linking topographic, demographic, utility, facility, image, and other geo-referenced data. The system provides a graphic interface to relational databases and supports decision making processes such as planning, design, maintenance and repair, and emergency response.
Past and Present Large Solid Rocket Motor Test Capabilities
NASA Technical Reports Server (NTRS)
Kowalski, Robert R.; Owen, David B., II
2011-01-01
A study was performed to identify the current and historical trends in the capability of solid rocket motor testing in the United States. The study focused on test positions capable of testing solid rocket motors of at least 10,000 lbf thrust. Top-level information was collected for two distinct data points plus/minus a few years: 2000 (Y2K) and 2010 (Present). Data was combined from many sources, but primarily focused on data from the Chemical Propulsion Information Analysis Center s Rocket Propulsion Test Facilities Database, and heritage Chemical Propulsion Information Agency/M8 Solid Rocket Motor Static Test Facilities Manual. Data for the Rocket Propulsion Test Facilities Database and heritage M8 Solid Rocket Motor Static Test Facilities Manual is provided to the Chemical Propulsion Information Analysis Center directly from the test facilities. Information for each test cell for each time period was compiled and plotted to produce a graphical display of the changes for the nation, NASA, Department of Defense, and commercial organizations during the past ten years. Major groups of plots include test facility by geographic location, test cells by status/utilization, and test cells by maximum thrust capability. The results are discussed.
Community Discharge of Nursing Home Residents: The Role of Facility Characteristics.
Holup, Amanda A; Gassoumis, Zachary D; Wilber, Kathleen H; Hyer, Kathryn
2016-04-01
Using a socio-ecological model, this study examines the influence of facility characteristics on the transition of nursing home residents to the community after a short stay (within 90 days of admission) or long stay (365 days of admission) across states with different long-term services and supports systems. Data were drawn from the Minimum Data Set, the federal Online Survey, Certification, and Reporting (OSCAR) database, the Area Health Resource File, and the LTCFocUs.org database for all free-standing, certified nursing homes in California (n = 1,127) and Florida (n = 657) from July 2007 to June 2008. Hierarchical generalized linear models were used to examine the impact of facility characteristics on the probability of transitioning to the community. Facility characteristics, including size, occupancy, ownership, average length of stay, proportion of Medicare and Medicaid residents, and the proportion of residents admitted from acute care facilities are associated with discharge but differed by state and whether the discharge occurred after a short or long stay. Short- and long-stay nursing home discharge to the community is affected by resident, facility, and sometimes market characteristics, with Medicaid consistently influencing discharge in both states. © Health Research and Educational Trust.
Efficiency of inpatient orthopedic surgery in Japan: a medical claims database analysis.
Nakata, Yoshinori; Yoshimura, Tatsuya; Watanabe, Yuichi; Otake, Hiroshi; Oiso, Giichiro; Sawa, Tomohiro
2017-07-10
Purpose The purpose of this paper is to determine the characteristics of healthcare facilities that produce the most efficient inpatient orthopedic surgery using a large-scale medical claims database in Japan. Design/methodology/approach Reimbursement claims data were obtained from April 1 through September 30, 2014. Input-oriented Banker-Charnes-Cooper model of data envelopment analysis (DEA) was employed. The decision-making unit was defined as a healthcare facility where orthopedic surgery was performed. Inputs were defined as the length of stay, the number of beds, and the total costs of expensive surgical devices. Output was defined as total surgical fees for each surgery. Efficiency scores of healthcare facilities were compared among different categories of healthcare facilities. Findings The efficiency scores of healthcare facilities with a diagnosis-procedure combination (DPC) reimbursement were significantly lower than those without DPC ( p=0.0000). All the efficiency scores of clinics with beds were 1. Their efficiency scores were significantly higher than those of university hospitals, public hospitals, and other hospitals ( p=0.0000). Originality/value This is the first research that applied DEA for orthopedic surgery in Japan. The healthcare facilities with DPC reimbursement were less efficient than those without DPC. The clinics with beds were the most efficient among all types of management bodies of healthcare facilities.
Bergeron, Catherine; Fleet, Richard; Tounkara, Fatoumata Korika; Lavallée-Bourget, Isabelle; Turgeon-Pelchat, Catherine
2017-12-28
Rural emergency departments (EDs) are an important gateway to care for the 20% of Canadians who reside in rural areas. Less than 15% of Canadian rural EDs have access to a computed tomography (CT) scanner. We hypothesized that a significant proportion of inter-facility transfers from rural hospitals without CT scanners are for CT imaging. Our objective was to assess inter-facility transfers for CT imaging in a rural ED without a CT scanner. We selected a rural ED that offers 24/7 medical care with admission beds but no CT scanner. Descriptive statistics were collected from 2010 to 2015 on total ED visits and inter-facility transfers. Data was accessible through hospital and government databases. Between 2010 and 2014, there were respectively 13,531, 13,524, 13,827, 12,883, and 12,942 ED visits, with an average of 444 inter-facility transfers. An average of 33% (148/444) of inter-facility transfers were to a rural referral centre with a CT scan, with 84% being for CT scan. Inter-facility transfers incur costs and potential delays in patient diagnosis and management, yet current databases could not capture transfer times. Acquiring a CT scan may represent a reasonable opportunity for the selected rural hospital considering the number of required transfers.
ERIC Educational Resources Information Center
Scheideman, Dale; Dufresne, Ray
2001-01-01
Nevada's Clark County, the fastest growing school district in the nation, uses a life-cycle facilities management approach that monitors the individual components of each building on a database. The district's 10-year building program is addressing facilities infrastructure renewal, deferred maintenance, replacement, and new school construction.…
1992-07-01
database programs, such as dBase or Microsoft Excell, to yield statistical reports that can profile the health care facility . Ladeen (1989) feels that the...service specific space status report would be beneficial to the specific service(s) under study, it would not provide sufficient data for facility -wide...change in the Master Space Plan. The revised methodology also provides a mechanism and forum for spuce management education within the facility . The
Radiation therapy facilities in the United States
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ballas, Leslie K.; Elkin, Elena B.; Schrag, Deborah
2006-11-15
Purpose: About half of all cancer patients in the United States receive radiation therapy as a part of their cancer treatment. Little is known, however, about the facilities that currently deliver external beam radiation. Our goal was to construct a comprehensive database of all radiation therapy facilities in the United States that can be used for future health services research in radiation oncology. Methods and Materials: From each state's health department we obtained a list of all facilities that have a linear accelerator or provide radiation therapy. We merged these state lists with information from the American Hospital Association (AHA),more » as well as 2 organizations that audit the accuracy of radiation machines: the Radiologic Physics Center (RPC) and Radiation Dosimetry Services (RDS). The comprehensive database included all unique facilities listed in 1 or more of the 4 sources. Results: We identified 2,246 radiation therapy facilities operating in the United States as of 2004-2005. Of these, 448 (20%) facilities were identified through state health department records alone and were not listed in any other data source. Conclusions: Determining the location of the 2,246 radiation facilities in the United States is a first step in providing important information to radiation oncologists and policymakers concerned with access to radiation therapy services, the distribution of health care resources, and the quality of cancer care.« less
NASA Technical Reports Server (NTRS)
Knighton, Donna L.
1992-01-01
A Flight Test Engineering Database Management System (FTE DBMS) was designed and implemented at the NASA Dryden Flight Research Facility. The X-29 Forward Swept Wing Advanced Technology Demonstrator flight research program was chosen for the initial system development and implementation. The FTE DBMS greatly assisted in planning and 'mass production' card preparation for an accelerated X-29 research program. Improved Test Plan tracking and maneuver management for a high flight-rate program were proven, and flight rates of up to three flights per day, two times per week were maintained.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Melius, C
2007-12-05
The epidemiological and economic modeling of poultry diseases requires knowing the size, location, and operational type of each poultry type operation within the US. At the present time, the only national database of poultry operations that is available to the general public is the USDA's 2002 Agricultural Census data, published by the National Agricultural Statistics Service, herein referred to as the 'NASS data'. The NASS data provides census data at the county level on poultry operations for various operation types (i.e., layers, broilers, turkeys, ducks, geese). However, the number of farms and sizes of farms for the various types aremore » not independent since some facilities have more than one type of operation. Furthermore, some data on the number of birds represents the number sold, which does not represent the number of birds present at any given time. In addition, any data tabulated by NASS that could identify numbers of birds or other data reported by an individual respondent is suppressed by NASS and coded with a 'D'. To be useful for epidemiological and economic modeling, the NASS data must be converted into a unique set of facility types (farms having similar operational characteristics). The unique set must not double count facilities or birds. At the same time, it must account for all the birds, including those for which the data has been suppressed. Therefore, several data processing steps are required to work back from the published NASS data to obtain a consistent database for individual poultry operations. This technical report documents data processing steps that were used to convert the NASS data into a national poultry facility database with twenty-six facility types (7 egg-laying, 6 broiler, 1 backyard, 3 turkey, and 9 others, representing ducks, geese, ostriches, emus, pigeons, pheasants, quail, game fowl breeders and 'other'). The process involves two major steps. The first step defines the rules used to estimate the data that is suppressed within the NASS database. The first step is similar to the first step used to estimate suppressed data for livestock [Melius et al (2006)]. The second step converts the NASS poultry types into the operational facility types used by the epidemiological and economic model. We also define two additional facility types for high and low risk poultry backyards, and an additional two facility types for live bird markets and swap meets. The distribution of these additional facility types among counties is based on US population census data. The algorithm defining the number of premises and the corresponding distribution among counties and the resulting premises density plots for the continental US are provided.« less
42 CFR 436.407 - Types of acceptable documentary evidence of citizenship.
Code of Federal Regulations, 2011 CFR
2011-10-01
... perjury by a residential care facility director or administrator on behalf of an institutionalized... State database subsequent changes in eligibility should not require repeating the documentation of... databases to verify that the individual already established citizenship. (6) CMS requires that as a check...
The Space Systems Environmental Test Facility Database (SSETFD), Website Development Status
NASA Technical Reports Server (NTRS)
Snyder, James M.
2008-01-01
The Aerospace Corporation has been developing a database of U.S. environmental test laboratory capabilities utilized by the space systems hardware development community. To date, 19 sites have been visited by The Aerospace Corporation and verbal agreements reached to include their capability descriptions in the database. A website is being developed to make this database accessible by all interested government, civil, university and industry personnel. The website will be accessible by all interested in learning more about the extensive collective capability that the US based space industry has to offer. The Environments, Test & Assessment Department within The Aerospace Corporation will be responsible for overall coordination and maintenance of the database. Several US government agencies are interested in utilizing this database to assist in the source selection process for future spacecraft programs. This paper introduces the website by providing an overview of its development, location and search capabilities. It will show how the aerospace community can apply this new tool as a way to increase the utilization of existing lab facilities, and as a starting point for capital expenditure/upgrade trade studies. The long term result is expected to be increased utilization of existing laboratory capability and reduced overall development cost of space systems hardware. Finally, the paper will present the process for adding new participants, and how the database will be maintained.
Chan, J Hy; Law, C K; Hamblion, E; Fung, H; Rudge, J
2017-04-01
Hand, foot, and mouth disease continues to cause seasonal epidemics in the Asia-Pacific Region. Since the current Enterovirus 71 vaccines do not provide cross-protection for all Enterovirus species that cause hand, foot, and mouth disease, there is an urgent need to identify appropriate detection tools and best practice to prevent its transmission and to effectively control its outbreaks. This systematic review aimed to identify characteristics of outbreak and assess the impact and effectiveness of detection tools and public health preventive measures to interrupt transmission. The findings will be used to recommend policy on the most effective responses and interventions in Hong Kong to effectively minimise and contain the spread of the disease within childcare facilities. We searched the following databases for primary studies written in Chinese or English: MEDLINE, EMBASE, Global Health, WHO Western Pacific Region Index Medicus database, China National Knowledge Infrastructure Databases, and Chinese Scientific Journals Database. Studies conducted during or retrospective to outbreaks of hand, foot, and mouth disease caused by Enterovirus 71 from 1980 to 2012 within childcare facilities and with a study population of 0 to 6 years old were included. Sixteen studies conducted on outbreaks in China showed that hand, foot, and mouth disease spread rapidly within the facility, with an outbreak length of 4 to 46 days, especially in those with delayed notification (after 24 hours) of clustered outbreak (with five or more cases discovered within the facility) to the local Center for Disease Control and Prevention and delayed implementation of a control response. The number of classes affected ranged from 1 to 13, and the attack rate for children ranged from 0.97% to 28.18%. Communication between key stakeholders about outbreak confirmation, risk assessment, and surveillance should be improved. Effective communication facilitates timely notification (within 24 hours) of clustered outbreaks to a local Center for Disease Control and Prevention. Timely implementation of a control response is effective in minimising incidence and length of an outbreak in childcare facilities. The government should provide incentives for childcare facilities to train infection control specialists who can serve as the first contact, knowledge, and communication points, as well as facilitate exchange of information and provision of support across stakeholders during a communicable disease epidemic.
SPDF Data and Orbit Services Supporting Open Access, Use and Archiving of MMS Data
NASA Astrophysics Data System (ADS)
McGuire, R. E.; Bilitza, D.; Candey, R. M.; Chimiak, R.; Cooper, J. F.; Garcia, L. N.; Harris, B. T.; Johnson, R. C.; Kovalick, T. J.; Lal, N.; Leckner, H. A.; Liu, M. H.; Papitashvili, N. E.; Roberts, D. A.; Yurow, R. E.
2015-12-01
NASA's Space Physics Data Facility (SPDF) project is now serving MMS definitive and predictive interactive orbit plots, listings and conjunction calculations through our SSCWeb and 4D Orbit Viewer services. In March 2016 and in parallel with the MMS Science Data Center (SDC) at LASP, SPDF will begin publicly serving a complete set of MMS Level-2 and higher, survey and burst-mode science data products from all four spacecraft and all instruments. The initial Level-2 data available will be from September 2015 to early February 2016, with Level-2 products subsequently validated and publicly available with an approximate one month lag. All MMS Level-2 and higher data products are produced in standard CDF format with standard ISTP/SPDF metadata and will be served by SPDF through our CDAWeb data service, including our web services and associated APIs for IDL and Matlab users, and through direct FTP/HTTP directory browse and file downloads. SPDF's ingest, archival preservation and active serving of current MMS science data is part of our role as an active heliophysics final archive. SPDF's ingest of complete and current science data products from other active heliophysics missions with SPDF services will help enable coordinated and correlative MMS science analysis by the open international science community with current data from THEMIS, the Van Allen Probes and other missions including TWINS, Cluster, ACE, Wind, >120 ground magnetometer stations as well as instruments on the NOAA GOES and POES spacecraft. Please see the related Candey et.al. paper on "SPDF Ancillary Services and Technologies Supporting Open Access, Use and Archiving of MMS Data" for other aspects of what SPDF is doing. All SPDF data and services are available from the SPDF home page at http://spdf.gsfc.nasa.gov .
Ray Modeling Methods for Range Dependent Ocean Environments
1983-12-01
the eikonal equation, gives rise to equations for ray paths which are perpendicular to the wave fronts. Equation II.4, the transport equation, leads... databases for use by MEDUSA. The author has assisted in the installation of MEDUSA at computer facilities which possess databases containing archives of...sound velocity profiles, bathymetry, and bottom loss data. At each computer site, programs convert the archival data retrieved by the database system
Takahashi, Arata; Kumamaru, Hiraku; Tomotaki, Ai; Matsumura, Goki; Fukuchi, Eriko; Hirata, Yasutaka; Murakami, Arata; Hashimoto, Hideki; Ono, Minoru; Miyata, Hiroaki
2018-03-01
Japan Congenital Cardiovascluar Surgical Database (JCCVSD) is a nationwide registry whose data are used for health quality assessment and clinical research in Japan. We evaluated the completeness of case registration and the accuracy of recorded data components including postprocedural mortality and complications in the database via on-site data adjudication. We validated the records from JCCVSD 2010 to 2012 containing congenital cardiovascular surgery data performed in 111 facilities throughout Japan. We randomly chose nine facilities for site visit by the auditor team and conducted on-site data adjudication. We assessed whether the records in JCCVSD matched the data in the source materials. We identified 1,928 cases of eligible surgeries performed at the facilities, of which 1,910 were registered (99.1% completeness), with 6 cases of duplication and 1 inappropriate case registration. Data components including gender, age, and surgery time (hours) were highly accurate with 98% to 100% concordance. Mortality at discharge and at 30 and 90 postoperative days was 100% accurate. Among the five complications studied, reoperation was the most frequently observed, with 16 and 21 cases recorded in the database and source materials, respectively, having a sensitivity of 0.67 and a specificity of 0.99. Validation of JCCVSD database showed high registration completeness and high accuracy especially in the categorical data components. Adjudicated mortality was 100% accurate. While limited in numbers, the recorded cases of postoperative complications all had high specificities but had lower sensitivity (0.67-1.00). Continued activities for data quality improvement and assessment are necessary for optimizing the utility of these registries.
Comparison of PubMed, Scopus, Web of Science, and Google Scholar: strengths and weaknesses.
Falagas, Matthew E; Pitsouni, Eleni I; Malietzis, George A; Pappas, Georgios
2008-02-01
The evolution of the electronic age has led to the development of numerous medical databases on the World Wide Web, offering search facilities on a particular subject and the ability to perform citation analysis. We compared the content coverage and practical utility of PubMed, Scopus, Web of Science, and Google Scholar. The official Web pages of the databases were used to extract information on the range of journals covered, search facilities and restrictions, and update frequency. We used the example of a keyword search to evaluate the usefulness of these databases in biomedical information retrieval and a specific published article to evaluate their utility in performing citation analysis. All databases were practical in use and offered numerous search facilities. PubMed and Google Scholar are accessed for free. The keyword search with PubMed offers optimal update frequency and includes online early articles; other databases can rate articles by number of citations, as an index of importance. For citation analysis, Scopus offers about 20% more coverage than Web of Science, whereas Google Scholar offers results of inconsistent accuracy. PubMed remains an optimal tool in biomedical electronic research. Scopus covers a wider journal range, of help both in keyword searching and citation analysis, but it is currently limited to recent articles (published after 1995) compared with Web of Science. Google Scholar, as for the Web in general, can help in the retrieval of even the most obscure information but its use is marred by inadequate, less often updated, citation information.
Ten Years Experience In Geo-Databases For Linear Facilities Risk Assessment (Lfra)
NASA Astrophysics Data System (ADS)
Oboni, F.
2003-04-01
Keywords: geo-environmental, database, ISO14000, management, decision-making, risk, pipelines, roads, railroads, loss control, SAR, hazard identification ABSTRACT: During the past decades, characterized by the development of the Risk Management (RM) culture, a variety of different RM models have been proposed by governmental agencies in various parts of the world. The most structured models appear to have originated in the field of environmental RM. These models are briefly reviewed in the first section of the paper focusing the attention on the difference between Hazard Management and Risk Management and the need to use databases in order to allow retrieval of specific information and effective updating. The core of the paper reviews a number of different RM approaches, based on extensions of geo-databases, specifically developed for linear facilities (LF) in transportation corridors since the early 90s in Switzerland, Italy, Canada, the US and South America. The applications are compared in terms of methodology, capabilities and resources necessary to their implementation. The paper then focuses the attention on the level of detail that applications and related data have to attain. Common pitfalls related to decision making based on hazards rather than on risks are discussed. The paper focuses the last sections on the description of the next generation of linear facility RA application, including examples of results and discussion of future methodological research. It is shown that geo-databases should be linked to loss control and accident reports in order to maximize their benefits. The links between RA and ISO 14000 (environmental management code) are explicitly considered.
Minervino, Aline Costa; Duarte, Elisabeth Carmen
2016-03-01
This article outlines the results of a descriptive study that analyses loss and damage caused by hydrometeorological disasters in Brazil between 2010 and 2014 using the EM DAT (global) and S2iD (national) databases. The analysis shows major differences in the total number of disaster events included in the databases (EM-DAT = 36; S2iD = 4,070) and estimated costs of loss and damage (EM-DAT - R$ 9.2 billion; S2iD - R$331.4 billion). The analysis also shows that the five states most affected by these events are Santa Catarina, Rio Grande do Sul, Minas Gerais, São Paulo and Paraná in Brazil's South and Southeast regions and that these results are consistent with the findings of other studies. The costs of disasters were highest for housing, public infrastructure works, collectively used public facilities, other public service facilities, and state health and education facilities. The costs associated with public health facilities were also high. Despite their limitations, both databases demonstrated their usefulness for determining seasonal and long-term trends and patterns, and risk areas, and thus assist decision makers in identifying areas that are most affected by and vulnerable to natural disasters.
Interactive Querying Techniques for an Office Filing Facility.
ERIC Educational Resources Information Center
Morrissey, J. M.; And Others
1986-01-01
Proposes a "Model of Querying" for users of office filing facilities and discusses its motivation, aspects, attributes, and advantages. A review of current information systems and attempts to combine information retrieval, artificial intelligence, and database management techniques leads to conclusion that no resultant system is adequate…
Environmental factor(tm) system: RCRA hazardous waste handler information (on CD-ROM). Data file
DOE Office of Scientific and Technical Information (OSTI.GOV)
NONE
1995-11-01
Environmental Factor(trademark) RCRA Hazardous Waste Handler Information on CD-ROM unleashes the invaluable information found in two key EPA data sources on hazardous waste handlers and offers cradle-to-grave waste tracking. It`s easy to search and display: (1) Permit status, design capacity, and compliance history for facilities found in the EPA Research Conservation and Recovery Information System (RCRIS) program tracking database; (2) Detailed information on hazardous wastes generation, management, and minimization by companies who are large quantity generators; and (3) Data on the waste management practices of treatment, storage, and disposal (TSD) facilities from the EPA Biennial Reporting System which is collectedmore » every other year. Environmental Factor`s powerful database retrieval system lets you: (1) Search for RCRA facilities by permit type, SIC code, waste codes, corrective action, or violation information, TSD status, generator and transporter status, and more. (2) View compliance information - dates of evaluation, violation, enforcement, and corrective action. (3) Lookup facilities by waste processing categories of marketing, transporting, processing, and energy recovery. (4) Use owner/operator information and names, titles, and telephone numbers of project managers for prospecting. (5) Browse detailed data on TSD facility and large quantity generators` activities such as onsite waste treatment, disposal, or recycling, offsite waste received, and waste generation and management. The product contains databases, search and retrieval software on two CD-ROMs, an installation diskette and User`s Guide. Environmental Factor has online context-sensitive help from any screen and a printed User`s Guide describing installation and step-by-step procedures for searching, retrieving, and exporting.« less
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database.
HOED: Hypermedia Online Educational Database.
ERIC Educational Resources Information Center
Duval, E.; Olivie, H.
This paper presents HOED, a distributed hypermedia client-server system for educational resources. The aim of HOED is to provide a library facility for hyperdocuments that is accessible via the world wide web. Its main application domain is education. The HOED database not only holds the educational resources themselves, but also data describing…
Balancing Your Database Network Licenses against Your Budget.
ERIC Educational Resources Information Center
Bauer, Benjamin F.
1995-01-01
Discussion of choosing database access to satisfy users and budgetary constraints highlights a method to make educated estimates of simultaneous usage levels. Topics include pricing; advances in networks and CD-ROM technology; and two networking scenarios, one in an academic library and one in a corporate research facility. (LRW)
42 CFR 435.407 - Types of acceptable documentary evidence of citizenship.
Code of Federal Regulations, 2011 CFR
2011-10-01
... under penalty of perjury by a residential care facility director or administrator on behalf of an... documented and recorded in a State database subsequent changes in eligibility should not require repeating.... The State need only check its databases to verify that the individual already established citizenship...
2002-10-26
KENNEDY SPACE CENTER, FLA. -- A truck containing the Solar Radiation and Climate Experiment (SORCE) spacecraft arrives at KSC. The spacecraft will undergo final processing for launch. SORCE is equipped with four instruments that will measure variations in solar radiation much more accurately than anything now in use and observe some of the spectral properties of solar radiation for the first time. With data from NASA's SORCE mission, researchers should be able to follow how the Sun affects our climate now and in the future. The SORCE project is managed by NASA's Goddard Space Flight Center. The instruments on the SORCE spacecraft are built by the Laboratory for Atmospheric and Space Physics (LASP). Launch of SORCE aboard a Pegasus XL rocket is scheduled for mid-December 2002. Launch site is Cape Canaveral Air Force Station, Fla.
Schneider, Jeffrey C; Tan, Wei-Han; Goldstein, Richard; Mix, Jacqueline M; Niewczyk, Paulette; Divita, Margaret A; Ryan, Colleen M; Gerrard, Paul B; Kowalske, Karen; Zafonte, Ross
2013-01-01
A preliminary investigation of the burn rehabilitation population found a large variability of zero onset day frequency between facilities. Onset days is defined as the time from injury to inpatient rehabilitation admission; this variable has not been investigated in burn patients previously. This study explored if this finding was a facility-based phenomena or characteristic of burn inpatient rehabilitation patients. This study was a secondary analysis of Uniform Data System for Medical Rehabilitation (UDSmr) data from 2002 to 2007 examining inpatient rehabilitation characteristics among patients with burn injuries. Exclusion criteria were age less than 18 years and discharge against medical advice. Comparisons of demographic, medical and functional data were made between facilities with a high frequency of zero onset days versus facilities with a low frequency of zero onset days. A total of 4738 patients from 455 inpatient rehabilitation facilities were included. Twenty-three percent of the population exhibited zero onset days (n = 1103). Sixteen facilities contained zero onset patients; two facilities accounted for 97% of the zero onset subgroup. Facilities with a high frequency of zero onset day patients demonstrated significant differences in demographic, medical, and functional variables compared to the remainder of the study population. There were significantly more zero onset day admissions among burn patients (23%) than other diagnostic groups (0.5- 3.6%) in the Uniform Data System for Medical Rehabilitation database, but the majority (97%) came from two inpatient rehabilitation facilities. It is unexpected for patients with significant burn injury to be admitted to a rehabilitation facility on the day of injury. Future studies investigating burn rehabilitation outcomes using the Uniform Data System for Medical Rehabilitation database should exclude facilities with a high percentage of zero onset days, which are not representative of the burn inpatient rehabilitation population.
Interactive Database of Pulsar Flux Density Measurements
NASA Astrophysics Data System (ADS)
Koralewska, O.; Krzeszowski, K.; Kijak, J.; Lewandowski, W.
2012-12-01
The number of astronomical observations is steadily growing, giving rise to the need of cataloguing the obtained results. There are a lot of databases, created to store different types of data and serve a variety of purposes, e. g. databases providing basic data for astronomical objects (SIMBAD Astronomical Database), databases devoted to one type of astronomical object (ATNF Pulsar Database) or to a set of values of the specific parameter (Lorimer 1995 - database of flux density measurements for 280 pulsars on the frequencies up to 1606 MHz), etc. We found that creating an online database of pulsar flux measurements, provided with facilities for plotting diagrams and histograms, calculating mean values for a chosen set of data, filtering parameter values and adding new measurements by the registered users, could be useful in further studies on pulsar spectra.
School Facilities and Student Achievement in Industrial Countries: Evidence from the TIMSS
ERIC Educational Resources Information Center
Hopland, Arnt O.
2013-01-01
This paper studies the link between school facilities (buildings and grounds) and student achievement in eight countries using data from the TIMSS 2003 database. The results indicate a negative relationship, but the estimated coefficients are mainly insignificant. Interestingly, the coefficients differ heavily across countries. Whereas there seem…
Occupational radiation Exposure at Agreement State-Licensed Materials Facilities, 1997-2010
DOE Office of Scientific and Technical Information (OSTI.GOV)
U.S. Nuclear Regulatory Commission, Office of Nuclear Regulatory Research
The purpose of this report is to examine occupational radiation exposures received under Agreement State licensees. As such, this report reflects the occupational radiation exposure data contained in the Radiation Exposure Information and Reporting System (REIRS) database, for 1997 through 2010, from Agreement State-licensed materials facilities.
Venigalla, Sriram; Nead, Kevin T; Sebro, Ronnie; Guttmann, David M; Sharma, Sonam; Simone, Charles B; Levin, William P; Wilson, Robert J; Weber, Kristy L; Shabason, Jacob E
2018-03-15
Soft tissue sarcomas (STS) are rare malignancies that require complex multidisciplinary management. Therefore, facilities with high sarcoma case volume may demonstrate superior outcomes. We hypothesized that STS treatment at high-volume (HV) facilities would be associated with improved overall survival (OS). Patients aged ≥18 years with nonmetastatic STS treated with surgery and radiation therapy at a single facility from 2004 through 2013 were identified from the National Cancer Database. Facilities were dichotomized into HV and low-volume (LV) cohorts based on total case volume over the study period. OS was assessed using multivariable Cox regression with propensity score-matching. Patterns of care were assessed using multivariable logistic regression analysis. Of 9025 total patients, 1578 (17%) and 7447 (83%) were treated at HV and LV facilities, respectively. On multivariable analysis, high educational attainment, larger tumor size, higher grade, and negative surgical margins were statistically significantly associated with treatment at HV facilities; conversely, black race and non-metropolitan residence were negative predictors of treatment at HV facilities. On propensity score-matched multivariable analysis, treatment at HV facilities versus LV facilities was associated with improved OS (hazard ratio, 0.87, 95% confidence interval, 0.80-0.95; P = .001). Older age, lack of insurance, greater comorbidity, larger tumor size, higher tumor grade, and positive surgical margins were associated with statistically significantly worse OS. In this observational cohort study using the National Cancer Database, receipt of surgery and radiation therapy at HV facilities was associated with improved OS in patients with STS. Potential sociodemographic disparities limit access to care at HV facilities for certain populations. Our findings highlight the importance of receipt of care at HV facilities for patients with STS and warrant further study into improving access to care at HV facilities. Copyright © 2017 Elsevier Inc. All rights reserved.
Long Duration Exposure Facility (LDEF) optical systems SIG summary and database
NASA Astrophysics Data System (ADS)
Bohnhoff-Hlavacek, Gail
1992-09-01
The main objectives of the Long Duration Exposure Facility (LDEF) Optical Systems Special Investigative Group (SIG) Discipline are to develop a database of experimental findings on LDEF optical systems and elements hardware, and provide an optical system overview. Unlike the electrical and mechanical disciplines, the optics effort relies primarily on the testing of hardware at the various principal investigator's laboratories, since minimal testing of optical hardware was done at Boeing. This is because all space-exposed optics hardware are part of other individual experiments. At this time, all optical systems and elements testing by experiment investigator teams is not complete, and in some cases has hardly begun. Most experiment results to date, document observations and measurements that 'show what happened'. Still to come from many principal investigators is a critical analysis to explain 'why it happened' and future design implications. The original optical system related concerns and the lessons learned at a preliminary stage in the Optical Systems Investigations are summarized. The design of the Optical Experiments Database and how to acquire and use the database to review the LDEF results are described.
Arc Jet Facility Test Condition Predictions Using the ADSI Code
NASA Technical Reports Server (NTRS)
Palmer, Grant; Prabhu, Dinesh; Terrazas-Salinas, Imelda
2015-01-01
The Aerothermal Design Space Interpolation (ADSI) tool is used to interpolate databases of previously computed computational fluid dynamic solutions for test articles in a NASA Ames arc jet facility. The arc jet databases are generated using an Navier-Stokes flow solver using previously determined best practices. The arc jet mass flow rates and arc currents used to discretize the database are chosen to span the operating conditions possible in the arc jet, and are based on previous arc jet experimental conditions where possible. The ADSI code is a database interpolation, manipulation, and examination tool that can be used to estimate the stagnation point pressure and heating rate for user-specified values of arc jet mass flow rate and arc current. The interpolation is performed in the other direction (predicting mass flow and current to achieve a desired stagnation point pressure and heating rate). ADSI is also used to generate 2-D response surfaces of stagnation point pressure and heating rate as a function of mass flow rate and arc current (or vice versa). Arc jet test data is used to assess the predictive capability of the ADSI code.
Long Duration Exposure Facility (LDEF) optical systems SIG summary and database
NASA Technical Reports Server (NTRS)
Bohnhoff-Hlavacek, Gail
1992-01-01
The main objectives of the Long Duration Exposure Facility (LDEF) Optical Systems Special Investigative Group (SIG) Discipline are to develop a database of experimental findings on LDEF optical systems and elements hardware, and provide an optical system overview. Unlike the electrical and mechanical disciplines, the optics effort relies primarily on the testing of hardware at the various principal investigator's laboratories, since minimal testing of optical hardware was done at Boeing. This is because all space-exposed optics hardware are part of other individual experiments. At this time, all optical systems and elements testing by experiment investigator teams is not complete, and in some cases has hardly begun. Most experiment results to date, document observations and measurements that 'show what happened'. Still to come from many principal investigators is a critical analysis to explain 'why it happened' and future design implications. The original optical system related concerns and the lessons learned at a preliminary stage in the Optical Systems Investigations are summarized. The design of the Optical Experiments Database and how to acquire and use the database to review the LDEF results are described.
ERIC Educational Resources Information Center
Kreger, Michael D.
This annotated bibliography contains 167 citations of training materials for animal facility personnel that were enbtered in the AGRICOLA database between January 1979 and February 1995. Citations of journal articles, books, and audiovisual materials are included. A wide variety of publication types are represented, including the following:…
Social Work Literature Searching: Current Issues with Databases and Online Search Engines
ERIC Educational Resources Information Center
McGinn, Tony; Taylor, Brian; McColgan, Mary; McQuilkan, Janice
2016-01-01
Objectives: To compare the performance of a range of search facilities; and to illustrate the execution of a comprehensive literature search for qualitative evidence in social work. Context: Developments in literature search methods and comparisons of search facilities help facilitate access to the best available evidence for social workers.…
Environmental Factor{trademark} system: RCRA hazardous waste handler information
DOE Office of Scientific and Technical Information (OSTI.GOV)
NONE
1999-03-01
Environmental Factor{trademark} RCRA Hazardous Waste Handler Information on CD-ROM unleashes the invaluable information found in two key EPA data sources on hazardous waste handlers and offers cradle-to-grave waste tracking. It`s easy to search and display: (1) Permit status, design capacity and compliance history for facilities found in the EPA Resource Conservation and Recovery Information System (RCRIS) program tracking database; (2) Detailed information on hazardous wastes generation, management and minimization by companies who are large quantity generators, and (3) Data on the waste management practices of treatment, storage and disposal (TSD) facilities from the EPA Biennial Reporting System which is collectedmore » every other year. Environmental Factor`s powerful database retrieval system lets you: (1) Search for RCRA facilities by permit type, SIC code, waste codes, corrective action or violation information, TSD status, generator and transporter status and more; (2) View compliance information -- dates of evaluation, violation, enforcement and corrective action; (3) Lookup facilities by waste processing categories of marketing, transporting, processing and energy recovery; (4) Use owner/operator information and names, titles and telephone numbers of project managers for prospecting; and (5) Browse detailed data on TSD facility and large quantity generators` activities such as onsite waste treatment, disposal, or recycling, offsite waste received, and waste generation and management. The product contains databases, search and retrieval software on two CD-ROMs, an installation diskette and User`s Guide. Environmental Factor has online context-sensitive help from any screen and a printed User`s Guide describing installation and step-by-step procedures for searching, retrieving and exporting. Hotline support is also available for no additional charge.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Smith, A.E.; Tschanz, J.; Monarch, M.
1996-05-01
The Air Quality Utility Information System (AQUIS) is a database management system that operates under dBASE IV. It runs on an IBM-compatible personal computer (PC) with MS DOS 5.0 or later, 4 megabytes of memory, and 30 megabytes of disk space. AQUIS calculates emissions for both traditional and toxic pollutants and reports emissions in user-defined formats. The system was originally designed for use at 7 facilities of the Air Force Materiel Command, and now more than 50 facilities use it. Within the last two years, the system has been used in support of Title V permit applications at Department ofmore » Defense facilities. Growth in the user community, changes and additions to reference emission factor data, and changing regulatory requirements have demanded additions and enhancements to the system. These changes have ranged from adding or updating an emission factor to restructuring databases and adding new capabilities. Quality assurance (QA) procedures have been developed to ensure that emission calculations are correct even when databases are reconfigured and major changes in calculation procedures are implemented. This paper describes these QA and updating procedures. Some user facilities include light industrial operations associated with aircraft maintenance. These facilities have operations such as fiberglass and composite layup and plating operations for which standard emission factors are not available or are inadequate. In addition, generally applied procedures such as material balances may need special treatment to work in an automated environment, for example, in the use of oils and greases and when materials such as polyurethane paints react chemically during application. Some techniques used in these situations are highlighted here. To provide a framework for the main discussions, this paper begins with a description of AQUIS.« less
Price, Curtis V.; Maupin, Molly A.
2014-01-01
The purpose of this report is to document the PSDB and explain the methods used to populate and update the data from the SDWIS, State datasets, and map and geospatial imagery. This report describes 3 data tables and 11 domain tables, including field contents, data sources, and relations between tables. Although the PSDB database is not available to the general public, this information should be useful for others who are developing other database systems to store and analyze public-supply system and facility data.
Aerodynamic Characteristics, Database Development and Flight Simulation of the X-34 Vehicle
NASA Technical Reports Server (NTRS)
Pamadi, Bandu N.; Brauckmann, Gregory J.; Ruth, Michael J.; Fuhrmann, Henri D.
2000-01-01
An overview of the aerodynamic characteristics, development of the preflight aerodynamic database and flight simulation of the NASA/Orbital X-34 vehicle is presented in this paper. To develop the aerodynamic database, wind tunnel tests from subsonic to hypersonic Mach numbers including ground effect tests at low subsonic speeds were conducted in various facilities at the NASA Langley Research Center. Where wind tunnel test data was not available, engineering level analysis is used to fill the gaps in the database. Using this aerodynamic data, simulations have been performed for typical design reference missions of the X-34 vehicle.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nelson, J. G.; Morton, R. L.; Castillo, C.
2011-02-01
A multi-level (facility and programmatic) risk assessment was conducted for the facilities in the Nevada National Security Site (NNSS) Readiness in Technical Base and Facilities (RTBF) Program and results were included in a new Risk Management Plan (RMP), which was incorporated into the fiscal year (FY) 2010 Integrated Plans. Risks, risk events, probability, consequence(s), and mitigation strategies were identified and captured, for most scope areas (i.e., risk categories) during the facilitated risk workshops. Risk mitigations (i.e., efforts in addition to existing controls) were identified during the facilitated risk workshops when the risk event was identified. Risk mitigation strategies fell intomore » two broad categories: threats or opportunities. Improvement projects were identified and linked to specific risks they mitigate, making the connection of risk reduction through investments for the annual Site Execution Plan. Due to the amount of that was collected, analysis to be performed, and reports to be generated, a Risk Assessment/ Management Tool (RAMtool) database was developed to analyze the risks in real-time, at multiple levels, which reinforced the site-level risk management process and procedures. The RAMtool database was developed and designed to assist in the capturing and analysis of the key elements of risk: probability, consequence, and impact. The RAMtool calculates the facility-level and programmatic-level risk factors to enable a side-by-side comparison to see where the facility manager and program manager should focus their risk reduction efforts and funding. This enables them to make solid decisions on priorities and funding to maximize the risk reduction. A more active risk management process was developed where risks and opportunities are actively managed, monitored, and controlled by each facility more aggressively and frequently. risk owners have the responsibility and accountability to manage their assigned risk in real-time, using the RAMtool database.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tynan, Mark C.; Russell, Glenn P.; Perry, Frank V.
These associated tables, references, notes, and report present a synthesis of some notable geotechnical and engineering information used to create four interactive layer maps for selected: 1) deep mines and shafts; 2) existing, considered or planned radioactive waste management deep underground studies or disposal facilities 3) deep large diameter boreholes, and 4) physics underground laboratories and facilities from around the world. These data are intended to facilitate user access to basic information and references regarding “deep underground” facilities, history, activities, and plans. In general, the interactive maps and database provide each facility’s approximate site location, geology, and engineered features (e.g.:more » access, geometry, depth, diameter, year of operations, groundwater, lithology, host unit name and age, basin; operator, management organization, geographic data, nearby cultural features, other). Although the survey is not comprehensive, it is representative of many of the significant existing and historical underground facilities discussed in the literature addressing radioactive waste management and deep mined geologic disposal safety systems. The global survey is intended to support and to inform: 1) interested parties and decision makers; 2) radioactive waste disposal and siting option evaluations, and 3) safety case development applicable to any mined geologic disposal facility as a demonstration of historical and current engineering and geotechnical capabilities available for use in deep underground facility siting, planning, construction, operations and monitoring.« less
Landsbergis, Paul A; Janevic, Teresa; Rothenberg, Laura; Adamu, Mohammed T; Johnson, Sylvia; Mirer, Franklin E
2013-07-01
We examined the association between long work hours, assembly line work and stress-related diseases utilizing objective health and employment data from an employer's administrative databases. A North American automobile manufacturing company provided data for claims for sickness, accident and disability insurance (work absence of at least 4 days) for cardiovascular disease (CVD), hypertension and psychological disorders, employee demographics, and facility hours worked per year for 1996-2001. Age-adjusted claim rates and age-adjusted rate ratios were calculated using Poisson regression, except for comparisons between production and skilled trades workers owing to lack of age denominator data by job category. Associations between overtime hours and claim rates by facility were examined by Poisson regression and multi-level Poisson regression. Claims for hypertension, coronary heart disease, CVD, and psychological disorders were associated with facility overtime hours. We estimate that a facility with 10 more overtime hours per week than another facility would have 4.36 more claims for psychological disorders, 2.33 more claims for CVD, and 3.29 more claims for hypertension per 1,000 employees per year. Assembly plants had the highest rates of claims for most conditions. Production workers tended to have higher rates of claims than skilled trades workers. Data from an auto manufacturer's administrative databases suggest that autoworkers working long hours, and assembly-line workers relative to skilled trades workers or workers in non-assembly facilities, have a higher risk of hypertension, CVD, and psychological disorders. Occupational disease surveillance and disease prevention programs need to fully utilize such administrative data. Copyright © 2013 Wiley Periodicals, Inc.
Maupin, Molly A.; Ivahnenko, Tamara
2011-01-01
Data from the United States Environmental Protection Agency Permit Compliance System national database were used to calculate annual total nitrogen (TN) and total phosphorus (TP) loads to surface waters from municipal and industrial facilities in six major regions of the United States for 1992, 1997, and 2002. Concentration and effluent flow data were examined for approximately 118,250 facilities in 45 states and the District of Columbia. Inconsistent and incomplete discharge locations, effluent flows, and effluent nutrient concentrations limited the use of these data for calculating nutrient loads. More concentrations were reported for major facilities, those discharging more than 1 million gallons per day, than for minor facilities, and more concentrations were reported for TP than for TN. Analytical methods to check and improve the quality of the Permit Compliance System data were used. Annual loads were calculated using "typical pollutant concentrations" to supplement missing concentrations based on the type and size of facilities. Annual nutrient loads for over 26,600 facilities were calculated for at least one of the three years. Sewage systems represented 74% of all TN loads and 58% of all TP loads. This work represents an initial set of data to develop a comprehensive and consistent national database of point-source nutrient loads. These loads can be used to inform a wide range of water-quality management, watershed modeling, and research efforts at multiple scales.
ERIC Educational Resources Information Center
Evans, John; Park, Betsy
This planning proposal recommends that Memphis State University Libraries make information on CD-ROM (compact disc--read only memory) available in the Reference Department by establishing an Information Retrieval Center (IRC). Following a brief introduction and statement of purpose, the library's databases, users, staffing, facilities, and…
Problems and programming for analysis of IUE high resolution data for variability
NASA Technical Reports Server (NTRS)
Grady, C. A.
1981-01-01
Observations of variability in stellar winds provide an important probe of their dynamics. It is crucial however to know that any variability seen in a data set can be clearly attributed to the star and not to instrumental or data processing effects. In the course of analysis of IUE high resolution data of alpha Cam and other O, B and Wolf-Rayet stars several effects were found which cause spurious variability or spurious spectral features in our data. Programming was developed to partially compensate for these effects using the Interactive Data language (IDL) on the LASP PDP 11/34. Use of an interactive language such as IDL is particularly suited to analysis of variability data as it permits use of efficient programs coupled with the judgement of the scientist at each stage of processing.
NASA Astrophysics Data System (ADS)
Li, X.; Temerin, M. A.; Monk, S.; Baker, D. N.; Reeves, G. D.
2002-05-01
The MeV electrons, also known as `killer electrons', have a deleterious impact on satellites through deep dielectric charging and the bodies of astronauts through radiation damage during extravehicular activity. Using a recently developed model based on the standard radial diffusion equation [Li et al., 2001], we show that the intensity of these MeV electrons at geosynchronous orbit can be quantitatively predicted 1-2 days in advance given knowledge of the solar wind. Our current model is operating in real-time, using real-time data from ACE and GOES-10, to make forecast of >2 MeV eletrons at geosynchronous orbit up to 48 hours in advance, the results are available on the web, currently updated every two hours (http://lasp.colorado.edu/~monk/xlf2.html).
Filmless PACS in a multiple facility environment
NASA Astrophysics Data System (ADS)
Wilson, Dennis L.; Glicksman, Robert A.; Prior, Fred W.; Siu, Kai-Yeung; Goldburgh, Mitchell M.
1996-05-01
A Picture Archiving and Communication System centered on a shared image file server can support a filmless hospital. Systems based on this architecture have proven themselves in over four years of clinical operation. Changes in healthcare delivery are causing radiology groups to support multiple facilities for remote clinic support and consolidation of services. There will be a corresponding need for communicating over a standardized wide area network (WAN). Interactive workflow, a natural extension to the single facility case, requires a means to work effectively and seamlessly across moderate to low speed communication networks. Several schemes for supporting a consortium of medical treatment facilities over a WAN are explored. Both centralized and distributed database approaches are evaluated against several WAN scenarios. Likewise, several architectures for distributing image file servers or buffers over a WAN are explored, along with the caching and distribution strategies that support them. An open system implementation is critical to the success of a wide area system. The role of the Digital Imaging and Communications in Medicine (DICOM) standard in supporting multi- facility and multi-vendor open systems is also addressed. An open system can be achieved by using a DICOM server to provide a view of the system-wide distributed database. The DICOM server interface to a local version of the global database lets a local workstation treat the multiple, distributed data servers as though they were one local server for purposes of examination queries. The query will recover information about the examination that will permit retrieval over the network from the server on which the examination resides. For efficiency reasons, the ability to build cross-facility radiologist worklists and clinician-oriented patient folders is essential. The technologies of the World-Wide-Web can be used to generate worklists and patient folders across facilities. A reliable broadcast protocol may be a convenient way to notify many different users and many image servers about new activities in the network of image servers. In addition to ensuring reliability of message delivery and global serialization of each broadcast message in the network, the broadcast protocol should not introduce significant communication overhead.
Sport and Social Inclusion: Evidence from the Performance of Public Leisure Facilities
ERIC Educational Resources Information Center
Liu, Yi-De
2009-01-01
In the UK, sport is increasingly recognized as a means for promoting social inclusion. However, evaluation, to date, is limited with regard to the achievement of social inclusion through sport. Based on the database of Sport England's National Benchmarking Service, this paper aims to investigate the extent to which public leisure facilities were…
EPA Facility Registry Service (FRS): CERCLIS
This data provides location and attribute information on Facilities regulated under the Comprehensive Environmental Responsibility Compensation and Liability Information System (CERCLIS) for a intranet web feature service . The data provided in this service are obtained from EPA's Facility Registry Service (FRS). The FRS is an integrated source of comprehensive (air, water, and waste) environmental information about facilities, sites or places. This service connects directly to the FRS database to provide this data as a feature service. FRS creates high-quality, accurate, and authoritative facility identification records through rigorous verification and management procedures that incorporate information from program national systems, state master facility records, data collected from EPA's Central Data Exchange registrations and data management personnel. Additional Information on FRS is available at the EPA website https://www.epa.gov/enviro/facility-registry-service-frs.
The unified database for the fixed target experiment BM@N
NASA Astrophysics Data System (ADS)
Gertsenberger, K. V.
2016-09-01
The article describes the developed database designed as comprehensive data storage of the fixed target experiment BM@N [1] at Joint Institute for Nuclear Research (JINR) in Dubna. The structure and purposes of the BM@N facility will be briefly presented. The scheme of the unified database and its parameters will be described in detail. The use of the BM@N database implemented on the PostgreSQL database management system (DBMS) allows one to provide user access to the actual information of the experiment. Also the interfaces developed for the access to the database will be presented. One was implemented as the set of C++ classes to access the data without SQL statements, the other-Web-interface being available on the Web page of the BM@N experiment.
Progress towards a Spacecraft-Associated Microbial Meta-database (SAMM)
NASA Astrophysics Data System (ADS)
Mogul, Rakesh; Keagy, Laura; Nava, Argelia; Zerehi, Farah
The microbial inventories within the assembly facilities for spacecraft represent the primary pool of forward contaminants that may compromise life-detection missions. Accordingly, we are constructing a meta-database of these microorganisms for the purpose of building a bioinformatic resource for planetary protection and astrobiology-related endeavors. Using student-led efforts, the meta-database is being constructed from literature reports and is inclusive of both isolated microorganisms and those solely detected through DNA-based techniques. The Spacecraft-Associated Microbial Meta-database (SAMM) currently includes over 800 entries that are organized using 32 meta-tags involving taxonomy, location of isolation (facility and component), category of characterization (culture and/or genetic), types of characterizations (e.g., culture, 16s rDNA, phylochip, FAME, and DNA hybridization), growth conditions, Gram stain, and general physiological traits (e.g., sporulation, extremotolerance, and respiration properties). Interrogations on the database show that the cleanrooms at Kennedy Space Center (KSC) are ~ 2-fold greater in diversity in bacterial genera when compared to the Jet Propulsion Laboratory (JPL), and that bacteria related to water, plant, and human environments are more often associated with the KSC-specific genera. These results are parallel to those reported in the literature, and hence serve as benchmarks demonstrating the bioinformatic potential of this meta-database. The ultimate plans for SAMM include public availability, expansion through crowdsourcing efforts, and potential use as a companion resource to the culture collections assembled by DSMZ and JPL.
Al-Safi, Zain A; Shavell, Valerie I; Hobson, Deslyn T G; Berman, Jay M; Diamond, Michael P
2013-01-01
The Manufacturer and User Facility Device Experience database may be useful for clinicians using a Food and Drug Administration-approved medical device to identify the occurrence of adverse events and complications. We sought to analyze and investigate reports associated with the Essure hysteroscopic sterilization system (Conceptus Inc., Mountain View, CA) using this database. Retrospective review of the Manufacturer and User Facility Device Experience database for events related to Essure hysteroscopic sterilization from November 2002 to February 2012 (Canadian Task Force Classification III). Online retrospective review. Online reports of patients who underwent Essure tubal sterilization. Essure tubal sterilization. Four hundred fifty-seven adverse events were reported in the study period. Pain was the most frequently reported event (217 events [47.5%]) followed by delivery catheter malfunction (121 events [26.4%]). Poststerilization pregnancy was reported in 61 events (13.3%), of which 29 were ectopic pregnancies. Other reported events included perforation (90 events [19.7%]), abnormal bleeding (44 events [9.6%]), and microinsert malposition (33 events [7.2%]). The evaluation and management of these events resulted in an additional surgical procedure in 270 cases (59.1%), of which 44 were hysterectomies. Sixty-one unintended poststerilization pregnancies were reported in the study period, of which 29 (47.5%) were ectopic gestations. Thus, ectopic pregnancy must be considered if a woman becomes pregnant after Essure hysteroscopic sterilization. Additionally, 44 women underwent hysterectomy after an adverse event reported to be associated with the use of the device. Copyright © 2013 AAGL. Published by Elsevier Inc. All rights reserved.
M4AST - A Tool for Asteroid Modelling
NASA Astrophysics Data System (ADS)
Birlan, Mirel; Popescu, Marcel; Irimiea, Lucian; Binzel, Richard
2016-10-01
M4AST (Modelling for asteroids) is an online tool devoted to the analysis and interpretation of reflection spectra of asteroids in the visible and near-infrared spectral intervals. It consists into a spectral database of individual objects and a set of routines for analysis which address scientific aspects such as: taxonomy, curve matching with laboratory spectra, space weathering models, and mineralogical diagnosis. Spectral data were obtained using groundbased facilities; part of these data are precompiled from the literature[1].The database is composed by permanent and temporary files. Each permanent file contains a header and two or three columns (wavelength, spectral reflectance, and the error on spectral reflectance). Temporary files can be uploaded anonymously, and are purged for the property of submitted data. The computing routines are organized in order to accomplish several scientific objectives: visualize spectra, compute the asteroid taxonomic class, compare an asteroid spectrum with similar spectra of meteorites, and computing mineralogical parameters. One facility of using the Virtual Observatory protocols was also developed.A new version of the service was released in June 2016. This new release of M4AST contains a database and facilities to model more than 6,000 spectra of asteroids. A new web-interface was designed. This development allows new functionalities into a user-friendly environment. A bridge system of access and exploiting the database SMASS-MIT (http://smass.mit.edu) allows the treatment and analysis of these data in the framework of M4AST environment.Reference:[1] M. Popescu, M. Birlan, and D.A. Nedelcu, "Modeling of asteroids: M4AST," Astronomy & Astrophysics 544, EDP Sciences, pp. A130, 2012.
Dogrusoz, U; Erson, E Z; Giral, E; Demir, E; Babur, O; Cetintas, A; Colak, R
2006-02-01
Patikaweb provides a Web interface for retrieving and analyzing biological pathways in the Patika database, which contains data integrated from various prominent public pathway databases. It features a user-friendly interface, dynamic visualization and automated layout, advanced graph-theoretic queries for extracting biologically important phenomena, local persistence capability and exporting facilities to various pathway exchange formats.
Baran, Michael C; Moseley, Hunter N B; Sahota, Gurmukh; Montelione, Gaetano T
2002-10-01
Modern protein NMR spectroscopy laboratories have a rapidly growing need for an easily queried local archival system of raw experimental NMR datasets. SPINS (Standardized ProteIn Nmr Storage) is an object-oriented relational database that provides facilities for high-volume NMR data archival, organization of analyses, and dissemination of results to the public domain by automatic preparation of the header files required for submission of data to the BioMagResBank (BMRB). The current version of SPINS coordinates the process from data collection to BMRB deposition of raw NMR data by standardizing and integrating the storage and retrieval of these data in a local laboratory file system. Additional facilities include a data mining query tool, graphical database administration tools, and a NMRStar v2. 1.1 file generator. SPINS also includes a user-friendly internet-based graphical user interface, which is optionally integrated with Varian VNMR NMR data collection software. This paper provides an overview of the data model underlying the SPINS database system, a description of its implementation in Oracle, and an outline of future plans for the SPINS project.
MouseNet database: digital management of a large-scale mutagenesis project.
Pargent, W; Heffner, S; Schäble, K F; Soewarto, D; Fuchs, H; Hrabé de Angelis, M
2000-07-01
The Munich ENU Mouse Mutagenesis Screen is a large-scale mutant production, phenotyping, and mapping project. It encompasses two animal breeding facilities and a number of screening groups located in the general area of Munich. A central database is required to manage and process the immense amount of data generated by the mutagenesis project. This database, which we named MouseNet(c), runs on a Sybase platform and will finally store and process all data from the entire project. In addition, the system comprises a portfolio of functions needed to support the workflow management of the core facility and the screening groups. MouseNet(c) will make all of the data available to the participating screening groups, and later to the international scientific community. MouseNet(c) will consist of three major software components:* Animal Management System (AMS)* Sample Tracking System (STS)* Result Documentation System (RDS)MouseNet(c) provides the following major advantages:* being accessible from different client platforms via the Internet* being a full-featured multi-user system (including access restriction and data locking mechanisms)* relying on a professional RDBMS (relational database management system) which runs on a UNIX server platform* supplying workflow functions and a variety of plausibility checks.
Materials, processes, and environmental engineering network
NASA Technical Reports Server (NTRS)
White, Margo M.
1993-01-01
The Materials, Processes, and Environmental Engineering Network (MPEEN) was developed as a central holding facility for materials testing information generated by the Materials and Processes Laboratory. It contains information from other NASA centers and outside agencies, and also includes the NASA Environmental Information System (NEIS) and Failure Analysis Information System (FAIS) data. Environmental replacement materials information is a newly developed focus of MPEEN. This database is the NASA Environmental Information System, NEIS, which is accessible through MPEEN. Environmental concerns are addressed regarding materials identified by the NASA Operational Environment Team, NOET, to be hazardous to the environment. An environmental replacement technology database is contained within NEIS. Environmental concerns about materials are identified by NOET, and control or replacement strategies are formed. This database also contains the usage and performance characteristics of these hazardous materials. In addition to addressing environmental concerns, MPEEN contains one of the largest materials databases in the world. Over 600 users access this network on a daily basis. There is information available on failure analysis, metals and nonmetals testing, materials properties, standard and commercial parts, foreign alloy cross-reference, Long Duration Exposure Facility (LDEF) data, and Materials and Processes Selection List data.
Silver, James; Fisher, William H; Silver, Emily
2015-06-01
A history of commitment to a mental health facility disqualifies applicants for gun licenses. Identifying such a history has become increasingly complex as the locus of confinement has become more diversified and privatized. In Massachusetts, prior to 2014, the databases used to identify individuals who would be disqualified on such grounds had not contemporaneously matched the evolution of the state's mental health systems. A survey of Massachusetts police chiefs, who, as in many jurisdictions, are charged with certifying qualification, indicates that some have broadened the scope of their background checks to include the experience of their officers with respect to certain applicants. The survey identifying these patterns, conducted in 2014, preceded by one month significant legislative reforms that mandate the modification of the reporting into a centralized database commitments to all types of mental health and substance use facilities, thus allowing identification of all commitments occurring in the state. The anticipated utilization of a different database mechanism, which has parallels in several other states, potentially streamlines the background check process, but raises numerous concerns that need to be addressed in developing and using such databases. Copyright © 2015 John Wiley & Sons, Ltd.
LSE-Sign: A lexical database for Spanish Sign Language.
Gutierrez-Sigut, Eva; Costello, Brendan; Baus, Cristina; Carreiras, Manuel
2016-03-01
The LSE-Sign database is a free online tool for selecting Spanish Sign Language stimulus materials to be used in experiments. It contains 2,400 individual signs taken from a recent standardized LSE dictionary, and a further 2,700 related nonsigns. Each entry is coded for a wide range of grammatical, phonological, and articulatory information, including handshape, location, movement, and non-manual elements. The database is accessible via a graphically based search facility which is highly flexible both in terms of the search options available and the way the results are displayed. LSE-Sign is available at the following website: http://www.bcbl.eu/databases/lse/.
Disaster Response and Preparedness Application: Emergency Environmental Response Tool (EERT)
NASA Technical Reports Server (NTRS)
Smoot, James; Carr, Hugh; Jester, Keith
2003-01-01
In 2000, the National Aeronautics and Space Administration (NASA) Environmental Office at the John C. Stennis Space Center (SSC) developed an Environmental Geographic Information Systems (EGIS) database. NASA had previously developed a GIS database at SSC to assist in the NASA Environmental Office's management of the Center. This GIS became the basis for the NASA-wide EGIS project, which was proposed after the applicability of the SSC database was demonstrated. Since its completion, the SSC EGIS has aided the Environmental Office with noise pollution modeling, land cover assessment, wetlands delineation, environmental hazards mapping, and critical habitat delineation for protected species. At SSC, facility management and safety officers are responsible for ensuring the physical security of the facilities, staff, and equipment as well as for responding to environmental emergencies, such as accidental releases of hazardous materials. All phases of emergency management (planning, mitigation, preparedness, and response) depend on data reliability and system interoperability from a variety of sources to determine the size and scope of the emergency operation. Because geospatial data are now available for all NASA facilities, it was suggested that this data could be incorporated into a computerized management information program to assist facility managers. The idea was that the information system could improve both the effectiveness and the efficiency of managing and controlling actions associated with disaster, homeland security, and other activities. It was decided to use SSC as a pilot site to demonstrate the efficacy of having a baseline, computerized management information system that ultimately was referred to as the Emergency Environmental Response Tool (EERT).
EPA Facility Registry Service (FRS): CAMDBS
This web feature service contains location and facility identification information from EPA's Facility Registry Service (FRS) for the subset of facilities that link to the Clean Air Markets Division Business System (CAMDBS). Administered by the EPA Clean Air Markets Division, within the Office of Air and Radiation, CAMDBS supports the implementation of market-based air pollution control programs, including the Acid Rain Program and regional programs designed to reduce the transport of ozone. FRS identifies and geospatially locates facilities, sites or places subject to environmental regulations or of environmental interest. Using vigorous verification and data management procedures, FRS integrates facility data from EPA's national program systems, other federal agencies, and State and tribal master facility records and provides EPA with a centrally managed, single source of comprehensive and authoritative information on facilities. This data set contains the subset of FRS integrated facilities that link to CAMDBS facilities once the CAMDBS data has been integrated into the FRS database. Additional information on FRS is available at the EPA website https://www.epa.gov/enviro/facility-registry-service-frs.
Hinckley, A; Bachand, A; Nuckols, J; Reif, J
2005-01-01
Background and Aims: Epidemiological studies of disinfection by-products (DBPs) and reproductive outcomes have been hampered by misclassification of exposure. In most epidemiological studies conducted to date, all persons living within the boundaries of a water distribution system have been assigned a common exposure value based on facility-wide averages of trihalomethane (THM) concentrations. Since THMs do not develop uniformly throughout a distribution system, assignment of facility-wide averages may be inappropriate. One approach to mitigate this potential for misclassification is to select communities for epidemiological investigations that are served by distribution systems with consistently low spatial variability of THMs. Methods and Results: A feasibility study was conducted to develop methods for community selection using the Information Collection Rule (ICR) database, assembled by the US Environmental Protection Agency. The ICR database contains quarterly DBP concentrations collected between 1997 and 1998 from the distribution systems of 198 public water facilities with minimum service populations of 100 000 persons. Facilities with low spatial variation of THMs were identified using two methods; 33 facilities were found with low spatial variability based on one or both methods. Because brominated THMs may be important predictors of risk for adverse reproductive outcomes, sites were categorised into three exposure profiles according to proportion of brominated THM species and average TTHM concentration. The correlation between THMs and haloacetic acids (HAAs) in these facilities was evaluated to see whether selection by total trihalomethanes (TTHMs) corresponds to low spatial variability for HAAs. TTHMs were only moderately correlated with HAAs (r = 0.623). Conclusions: Results provide a simple method for a priori selection of sites with low spatial variability from state or national public water facility datasets as a means to reduce exposure misclassification in epidemiological studies of DBPs. PMID:15961627
Cost effective nuclear commercial grade dedication
DOE Office of Scientific and Technical Information (OSTI.GOV)
Maletz, J.J.; Marston, M.J.
1991-01-01
This paper describes a new computerized database method to create/edit/view specification technical data sheets (mini-specifications) for procurement of spare parts for nuclear facility maintenance and to develop information that could support possible future facility life extension efforts. This method may reduce cost when compared with current manual methods. The use of standardized technical data sheets (mini-specifications) for items of the same category improves efficiency. This method can be used for a variety of tasks, including: Nuclear safety-related procurement; Non-safety related procurement; Commercial grade item procurement/dedication; Evaluation of replacement items. This program will assist the nuclear facility in upgrading its procurementmore » activities consistent with the recent NUMARC Procurement Initiative. Proper utilization of the program will assist the user in assuring that the procured items are correct for the applications, provide data to assist in detecting fraudulent materials, minimize human error in withdrawing database information, improve data retrievability, improve traceability, and reduce long-term procurement costs.« less
Microvax-based data management and reduction system for the regional planetary image facilities
NASA Technical Reports Server (NTRS)
Arvidson, R.; Guinness, E.; Slavney, S.; Weiss, B.
1987-01-01
Presented is a progress report for the Regional Planetary Image Facilities (RPIF) prototype image data management and reduction system being jointly implemented by Washington University and the USGS, Flagstaff. The system will consist of a MicroVAX with a high capacity (approx 300 megabyte) disk drive, a compact disk player, an image display buffer, a videodisk player, USGS image processing software, and SYSTEM 1032 - a commercial relational database management package. The USGS, Flagstaff, will transfer their image processing software including radiometric and geometric calibration routines, to the MicroVAX environment. Washington University will have primary responsibility for developing the database management aspects of the system and for integrating the various aspects into a working system.
McFarland, Michael J; Nelson, Tim M; Rasmussen, Steve L; Palmer, Glenn R; Olivas, Arthur C
2005-03-01
All U.S. Department of Defense (DoD) facilities are required under Executive Order (EO) 13148, "Greening the Government through Leadership in Environmental Management," to establish quality-based environmental management systems (EMSs) that support environmental decision-making and verification of continuous environmental improvement by December 31, 2005. Compliance with EO 13148 as well as other federal, state, and local environmental regulations places a significant information management burden on DoD facilities. Cost-effective management of environmental data compels DoD facilities to establish robust database systems that not only address the complex and multifaceted environmental monitoring, record-keeping, and reporting requirements demanded by these rules but enable environmental management decision-makers to gauge improvements in environmental performance. The Enterprise Environmental Safety and Occupational Health Management Information System (EESOH-MIS) is a new electronic database developed by the U.S. Air Force to manage both the data needs associated with regulatory compliance programs across its facilities as well as the non-regulatory environmental information that supports installation business practices. The U.S. Air Force, which has adopted the Plan-Do-Check-Act methodology as the EMS standard that it will employ to address EO 13148 requirements.
Malpractice litigation and nursing home quality of care.
Konetzka, R Tamara; Park, Jeongyoung; Ellis, Robert; Abbo, Elmer
2013-12-01
To assess the potential deterrent effect of nursing home litigation threat on nursing home quality. We use a panel dataset of litigation claims and Nursing Home Online Survey Certification and Reporting (OSCAR) data from 1995 to 2005 in six states: Florida, Illinois, Wisconsin, New Jersey, Missouri, and Delaware, for a total of 2,245 facilities. Claims data are from Westlaw's Adverse Filings database, a proprietary legal database, on all malpractice, negligence, and personal injury/wrongful death claims filed against nursing facilities. A lagged 2-year moving average of the county-level number of malpractice claims is used to represent the threat of litigation. We use facility fixed-effects models to examine the relationship between the threat of litigation and nursing home quality. We find significant increases in registered nurse-to-total staffing ratios in response to rising malpractice threat, and a reduction in pressure sores among highly staffed facilities. However, the magnitude of the deterrence effect is small. Deterrence in response to the threat of malpractice litigation is unlikely to lead to widespread improvements in nursing home quality. This should be weighed against other benefits and costs of litigation to assess the net benefit of tort reform. © Health Research and Educational Trust.
McIlroy, Simon Jon; Kirkegaard, Rasmus Hansen; McIlroy, Bianca; Nierychlo, Marta; Kristensen, Jannie Munk; Karst, Søren Michael; Albertsen, Mads
2017-01-01
Abstract Wastewater is increasingly viewed as a resource, with anaerobic digester technology being routinely implemented for biogas production. Characterising the microbial communities involved in wastewater treatment facilities and their anaerobic digesters is considered key to their optimal design and operation. Amplicon sequencing of the 16S rRNA gene allows high-throughput monitoring of these systems. The MiDAS field guide is a public resource providing amplicon sequencing protocols and an ecosystem-specific taxonomic database optimized for use with wastewater treatment facility samples. The curated taxonomy endeavours to provide a genus-level-classification for abundant phylotypes and the online field guide links this identity to published information regarding their ecology, function and distribution. This article describes the expansion of the database resources to cover the organisms of the anaerobic digester systems fed primary sludge and surplus activated sludge. The updated database includes descriptions of the abundant genus-level-taxa in influent wastewater, activated sludge and anaerobic digesters. Abundance information is also included to allow assessment of the role of emigration in the ecology of each phylotype. MiDAS is intended as a collaborative resource for the progression of research into the ecology of wastewater treatment, by providing a public repository for knowledge that is accessible to all interested in these biotechnologically important systems. Database URL: http://www.midasfieldguide.org PMID:28365734
Petition for the Administrator to Object to Title V Permit for Walter Coke Facility
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Petition Requesting the Administrator Object to Title V Permit for ABC Coke Facility
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Petition to Object to the Nucor Steel Facility, St. James Parish, Louisiana
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Aerodynamic Tests of the Space Launch System for Database Development
NASA Technical Reports Server (NTRS)
Pritchett, Victor E.; Mayle, Melody N.; Blevins, John A.; Crosby, William A.; Purinton, David C.
2014-01-01
The Aerosciences Branch (EV33) at the George C. Marshall Space Flight Center (MSFC) has been responsible for a series of wind tunnel tests on the National Aeronautics and Space Administration's (NASA) Space Launch System (SLS) vehicles. The primary purpose of these tests was to obtain aerodynamic data during the ascent phase and establish databases that can be used by the Guidance, Navigation, and Mission Analysis Branch (EV42) for trajectory simulations. The paper describes the test particulars regarding models and measurements and the facilities used, as well as database preparations.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hewett, R.
1997-12-31
This paper describes the strategy and computer processing system that NREL, the Virginia Department of Mines, Minerals and Energy (DMME) and the state energy office, are developing for computing solar attractiveness scores for state agencies and the individual facilities or buildings within each agency. In the case of an agency, solar attractiveness is a measure of that agency`s having a significant number of facilities for which solar has the potential to be promising. In the case of a facility, solar attractiveness is a measure of its potential for being good, economically viable candidate for a solar waste heating system. Virginiamore » State agencies are charged with reducing fossil energy and electricity use and expense. DMME is responsible for working with them to achieve the goals and for managing the state`s energy consumption and cost monitoring program. This is done using the Fast Accounting System for Energy Reporting (FASER) computerized energy accounting and tracking system and database. Agencies report energy use and expenses (by individual facility and energy type) to DMME quarterly. DMME is also responsible for providing technical and other assistance services to agencies and facilities interested in investigating use of solar. Since Virginia has approximately 80 agencies operating over 8,000 energy-consuming facilities and since DMME`s resources are limited, it is interested in being able to determine: (1) on which agencies to focus; (2) specific facilities on which to focus within each high-priority agency; and (3) irrespective of agency, which facilities are the most promising potential candidates for solar. The computer processing system described in this paper computes numerical solar attractiveness scores for the state`s agencies and the individual facilities using the energy use and cost data in the FASER system database and the state`s and NREL`s experience in implementing, testing and evaluating solar water heating systems in commercial and government facilities.« less
CAMEOfm is a database application where you can keep track of information (such as chemical inventories and contact information for facilities in your community) to assist in emergency response and planning.
1989-03-01
deficiencies of the present system. Specific objectives critical in de,’cloping an under- standing of the system are: " Identify all knowledge workers who use...to be negligible. The limited training require- ments are primarily due to the users existing knowledge of tK2 Oracle database system, the Users
Carré, N; Uhry, Z; Velten, M; Trétarre, B; Schvartz, C; Molinié, F; Maarouf, N; Langlois, C; Grosclaude, P; Colonna, M
2006-09-01
Cancer registries have a complete recording of new cancer cases occurring among residents of a specific geographic area. In France, they cover only 13% of the population. For thyroid cancer, where incidence rate is highly variable according to the district conversely to mortality, national incidence estimates are not accurate. A nationwide database, such as hospital discharge system, could improve this estimate but its positive predictive value and sensibility should be evaluated. The positive predictive value and the sensitivity for thyroid cancer case ascertainment (ICD-10) of the national hospital discharge system in 1999 and 2000 were estimated using the cancer registries database of 10 French districts as gold standard. The linkage of the two databases required transmission of nominative information from the health facilities of the study. From the registries database, a logistic regression analysis was carried out to identify factors related to being missed by the hospital discharge system. Among the 973 standardized discharge charts selected from the hospital discharge system, 866 were considered as true positive cases, and 107 as false positive. Forty five of the latter group were prevalent cases. The predictive positive value was 89% (95% confidence interval (CI): 87-91%) and did not differ according to the district (p=0,80). According to the cancer registries, 322 thyroid cancer cases diagnosed in 1999 or 2000 were missed by the hospital discharge system. Thus, the sensitivity of this latter system was 73% (70-76%) and varied significantly from 62% to 85% across districts (p<0.001) and according to the type of health facility (p<0.01). Predictive positive value of the French hospital discharge system for ascertainment of thyroid cancer cases is high and stable across districts. Sensitivity is lower and varies significantly according to the type of health facility and across districts, which limits the interest of this database for a national estimate of thyroid cancer incidence rate.
Switchable Chiral Selection of Aspartic Acids by Dynamic States of Brushite
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jiang, Wenge; Pan, Haihua; Zhang, Zhisen
Here, we show the chiral recognition and separation of aspartic acid (Asp) enantiomers by achiral brushite due to the asymmetries of their dynamical steps in its nonequilibrium states. Growing brushite has a higher adsorption affinity to d-Asp, while l-Asp is predominant on the dissolving brushite surface. Microstructural characterization reveals that chiral selection is mainly attributed to brushite [101] steps, which exhibit two different configurations during crystal growth and dissolution, respectively, with each preferring a distinct enantiomer due to this asymmetry. Because these transition step configurations have different stabilities, they subsequently result in asymmetric adsorption. Furthermore, by varying free energy barriersmore » through solution thermodynamic driving force (i.e., supersaturation), the dominant nonequilibrium intermediate states can be switched and chiral selection regulated. This finding highlights that the dynamic steps can be vital for chiral selection, which may provide a potential pathway for chirality generation through the dynamic nature.« less
Switchable Chiral Selection of Aspartic Acids by Dynamic States of Brushite
Jiang, Wenge; Pan, Haihua; Zhang, Zhisen; ...
2017-06-15
Here, we show the chiral recognition and separation of aspartic acid (Asp) enantiomers by achiral brushite due to the asymmetries of their dynamical steps in its nonequilibrium states. Growing brushite has a higher adsorption affinity to d-Asp, while l-Asp is predominant on the dissolving brushite surface. Microstructural characterization reveals that chiral selection is mainly attributed to brushite [101] steps, which exhibit two different configurations during crystal growth and dissolution, respectively, with each preferring a distinct enantiomer due to this asymmetry. Because these transition step configurations have different stabilities, they subsequently result in asymmetric adsorption. Furthermore, by varying free energy barriersmore » through solution thermodynamic driving force (i.e., supersaturation), the dominant nonequilibrium intermediate states can be switched and chiral selection regulated. This finding highlights that the dynamic steps can be vital for chiral selection, which may provide a potential pathway for chirality generation through the dynamic nature.« less
The Emirates Mars Mission Science Data Center
NASA Astrophysics Data System (ADS)
Craft, James; Hammadi, Omran Al; DeWolfe, Alexandria; Staley, Bryan; Schafer, Corey; Pankratz, Chris
2017-04-01
The Emirates Mars Mission (EMM), led by the Mohammed Bin Rashid Space Center (MBRSC) in Dubai, United Arab Emirates, is expected to arrive at Mars in January 2021. The EMM Science Data Center (SDC) is to be developed as a joint effort between MBRSC and the University of Colorado's Laboratory for Atmospheric and Space Physics (LASP). The EMM SDC is responsible for the production, management, distribution, and archiving of science data collected from the three instruments on board the Hope spacecraft. With the respective SDC teams on opposite sides of the world evolutionary techniques and cloud-based technologies are being utilized in the development of the EMM SDC. This presentation will provide a top down view of the EMM SDC, summarizing the cloud-based technologies being implemented in the design, as well as the tools, best practices, and lessons learned for software development and management in a geographically distributed team.
The Emirates Mars Mission Science Data Center
NASA Astrophysics Data System (ADS)
Craft, J.; Al Hammadi, O.; DeWolfe, A. W.; Staley, B.; Schafer, C.; Pankratz, C. K.
2017-12-01
The Emirates Mars Mission (EMM), led by the Mohammed Bin Rashid Space Center (MBRSC) in Dubai, United Arab Emirates, is expected to arrive at Mars in January 2021. The EMM Science Data Center (SDC) is to be developed as a joint effort between MBRSC and the University of Colorado's Laboratory for Atmospheric and Space Physics (LASP). The EMM SDC is responsible for the production, management, distribution, and archiving of science data collected from the three instruments on board the Hope spacecraft.With the respective SDC teams on opposite sides of the world evolutionary techniques and cloud-based technologies are being utilized in the development of the EMM SDC. This presentation will provide a top down view of the EMM SDC, summarizing the cloud-based technologies being implemented in the design, as well as the tools, best practices, and lessons learned for software development and management in a geographically distributed team.
Teschke, Omar; Soares, David Mendez
2016-03-29
Structures of crystallized deposits formed by the molecular self-assembly of aspartic acid and valine on silicon substrates were imaged by atomic force microscopy. Images of d- and l-aspartic acid crystal surfaces showing extended molecularly flat sheets or regions separated by single molecule thick steps are presented. Distinct orientation surfaces were imaged, which, combined with the single molecule step size, defines the geometry of the crystal. However, single molecule step growth also reveals the crystal chirality, i.e., growth orientations. The imaged ordered lattice of aspartic acid (asp) and valine (val) mostly revealed periodicities corresponding to bulk terminations, but a previously unreported molecular hexagonal lattice configuration was observed for both l-asp and l-val but not for d-asp or d-val. Atomic force microscopy can then be used to identify the different chiral forms of aspartic acid and valine crystals.
Ames Hybrid Combustion Facility
NASA Technical Reports Server (NTRS)
Zilliac, Greg; Karabeyoglu, Mustafa A.; Cantwell, Brian; Hunt, Rusty; DeZilwa, Shane; Shoffstall, Mike; Soderman, Paul T.; Bencze, Daniel P. (Technical Monitor)
2003-01-01
The report summarizes the design, fabrication, safety features, environmental impact, and operation of the Ames Hybrid-Fuel Combustion Facility (HCF). The facility is used in conducting research into the scalability and combustion processes of advanced paraffin-based hybrid fuels for the purpose of assessing their applicability to practical rocket systems. The facility was designed to deliver gaseous oxygen at rates between 0.5 and 16.0 kg/sec to a combustion chamber operating at pressures ranging from 300 to 900. The required run times were of the order of 10 to 20 sec. The facility proved to be robust and reliable and has been used to generate a database of regression-rate measurements of paraffin at oxygen mass flux levels comparable to those of moderate-sized hybrid rocket motors.
Region 5 Toxic Substances Control Act Producers
This dataset represents the query results from the Envirofacts database for facilities known as Chemical Manufacturers, Processors and Formulators (MPFs) with TSCA identification numbers located in Region 5.
Generic Entity Resolution in Relational Databases
NASA Astrophysics Data System (ADS)
Sidló, Csaba István
Entity Resolution (ER) covers the problem of identifying distinct representations of real-world entities in heterogeneous databases. We consider the generic formulation of ER problems (GER) with exact outcome. In practice, input data usually resides in relational databases and can grow to huge volumes. Yet, typical solutions described in the literature employ standalone memory resident algorithms. In this paper we utilize facilities of standard, unmodified relational database management systems (RDBMS) to enhance the efficiency of GER algorithms. We study and revise the problem formulation, and propose practical and efficient algorithms optimized for RDBMS external memory processing. We outline a real-world scenario and demonstrate the advantage of algorithms by performing experiments on insurance customer data.
Impact of medical director certification on nursing home quality of care.
Rowland, Frederick N; Cowles, Mick; Dickstein, Craig; Katz, Paul R
2009-07-01
This study tests the research hypothesis that certified medical directors are able to use their training, education, and knowledge to positively influence quality of care in US nursing homes. F-tag numbers were identified within the State Operations Manual that reflect dimensions of quality thought to be impacted by the medical director. A weighting system was developed based on the "scope and severity" level at which the nursing homes were cited for these specific tag numbers. Then homes led by certified medical directors were compared with homes led by medical directors not known to be certified. DATA/PARTICIPANTS: Data were obtained from the Centers for Medicare & Medicaid Services' Online Survey Certification and Reporting database for nursing homes. Homes with a certified medical director (547) were identified from the database of the American Medical Directors Association. The national survey database was used to compute a "standardized quality score" (zero representing best possible score and 1.0 representing average score) for each home, and the homes with certified medical directors compared with the other homes in the database. Regression analysis was then used to attempt to identify the most important contributors to measured quality score differences between the homes. The standardized quality score of facilities with certified medical directors (n=547) was 0.8958 versus 1.0037 for facilities without certified medical directors (n=15,230) (lower number represents higher quality). When nursing facility characteristics were added to the regression equation, the presence of a certified medical director accounted for up to 15% improvement in quality. The presence of certified medical directors is an independent predictor of quality in US nursing homes.
FlyAtlas: database of gene expression in the tissues of Drosophila melanogaster
Robinson, Scott W.; Herzyk, Pawel; Dow, Julian A. T.; Leader, David P.
2013-01-01
The FlyAtlas resource contains data on the expression of the genes of Drosophila melanogaster in different tissues (currently 25—17 adult and 8 larval) obtained by hybridization of messenger RNA to Affymetrix Drosophila Genome 2 microarrays. The microarray probe sets cover 13 250 Drosophila genes, detecting 12 533 in an unambiguous manner. The data underlying the original web application (http://flyatlas.org) have been restructured into a relational database and a Java servlet written to provide a new web interface, FlyAtlas 2 (http://flyatlas.gla.ac.uk/), which allows several additional queries. Users can retrieve data for individual genes or for groups of genes belonging to the same or related ontological categories. Assistance in selecting valid search terms is provided by an Ajax ‘autosuggest’ facility that polls the database as the user types. Searches can also focus on particular tissues, and data can be retrieved for the most highly expressed genes, for genes of a particular category with above-average expression or for genes with the greatest difference in expression between the larval and adult stages. A novel facility allows the database to be queried with a specific gene to find other genes with a similar pattern of expression across the different tissues. PMID:23203866
FlyAtlas: database of gene expression in the tissues of Drosophila melanogaster.
Robinson, Scott W; Herzyk, Pawel; Dow, Julian A T; Leader, David P
2013-01-01
The FlyAtlas resource contains data on the expression of the genes of Drosophila melanogaster in different tissues (currently 25-17 adult and 8 larval) obtained by hybridization of messenger RNA to Affymetrix Drosophila Genome 2 microarrays. The microarray probe sets cover 13,250 Drosophila genes, detecting 12,533 in an unambiguous manner. The data underlying the original web application (http://flyatlas.org) have been restructured into a relational database and a Java servlet written to provide a new web interface, FlyAtlas 2 (http://flyatlas.gla.ac.uk/), which allows several additional queries. Users can retrieve data for individual genes or for groups of genes belonging to the same or related ontological categories. Assistance in selecting valid search terms is provided by an Ajax 'autosuggest' facility that polls the database as the user types. Searches can also focus on particular tissues, and data can be retrieved for the most highly expressed genes, for genes of a particular category with above-average expression or for genes with the greatest difference in expression between the larval and adult stages. A novel facility allows the database to be queried with a specific gene to find other genes with a similar pattern of expression across the different tissues.
EPA Facility Registry Service (FRS): RCRA
This web feature service contains location and facility identification information from EPA's Facility Registry Service (FRS) for the subset of hazardous waste facilities that link to the Resource Conservation and Recovery Act Information System (RCRAInfo). EPA's comprehensive information system in support of the Resource Conservation and Recovery Act (RCRA) of 1976 and the Hazardous and Solid Waste Amendments (HSWA) of 1984, RCRAInfo tracks many types of information about generators, transporters, treaters, storers, and disposers of hazardous waste. FRS identifies and geospatially locates facilities, sites or places subject to environmental regulations or of environmental interest. Using vigorous verification and data management procedures, FRS integrates facility data from EPA's national program systems, other federal agencies, and State and tribal master facility records and provides EPA with a centrally managed, single source of comprehensive and authoritative information on facilities. This data set contains the subset of FRS integrated facilities that link to RCRAInfo hazardous waste facilities once the RCRAInfo data has been integrated into the FRS database. Additional information on FRS is available at the EPA website https://www.epa.gov/enviro/facility-registry-service-frs
Experiments of the origins of optical activity.
Bonner, W A; Flores, J J
1975-01-01
Two recent reports claim that (1) aqueous L-aspartic acid polymerizes faster than D-Asp in the presence of kaolin at 90 degrees, and (2) L-phenylalanine is adsorbed by kaolin more extensively than D-Phe at pH 4(the reverse being true at pH2). The novelty of these observations and their potential significance for the origin of optical activity has prompted us to duplicate these experiments using more sensitive methods. L- and D, L-Asp in 0.01 M solution were incubated with kaolin at 90 degrees for 8 days. Careful examination of the aqueous residues from such experiments failed to demonstrate any preferential polymerization of L-Asp over D-Asp, or indeed any significant gross polymerization of Asp at all. In other experiments 0.001 M solutions of D, L-Phe at pH 6 and pH 2 were stirred with large excesses of kaolin for 24 hr, and the aqueous extracts from these mixtures were examined for gross adsorption using the amino acid analyzer. No significant gross adsorption was noted. We then looked for asymmetric adsorption in the aqueous residues using optical rotatory dispersion, gas chromatography and thin layer chromatography. By none of these analytical criteria could we find any evidence whatsoever for the preferential adsorption of D- versus L-Phe from either pH 6 or pH 2 solutions. Finally, in experiments bearing on the origin of optical activity by parity violation during beta-decay, we have irradiated solid samples of D-, L- and D,L-leucine in a 61700 Ci Sr-90 source at Oak Ridge National Lab. for 1.34 yr (total dose: 4.2 x 10(8) rad). Gas chromatographic examination of the (appropriately derivitized) recovered samples showed that the L-Leu was 16.7% decomposed, the D-Leu 11.4% and theD,L-Leu 13.8% decomposed. The recovered D,L-Leu sample had a gas-chromatographically determined enantiomeric composition of 50.8% D-leu and 49.2% L-Leu. These data, though very close to experimental error, may indicate a slight preferential radiolysis of L-Leu compared to D-Leu by the Bremsstrahlung from Sr-90 beta-decay. These high intensity irradiation experiments are being continued on a prolonged basis in order to reach more definitive conclusions.
Nutrient Loadings to Streams of the Continental United States from Municipal and Industrial Effluent
Maupin, M.A.; Ivahnenko, T.
2011-01-01
Data from the United States Environmental Protection Agency Permit Compliance System national database were used to calculate annual total nitrogen (TN) and total phosphorus (TP) loads to surface waters from municipal and industrial facilities in six major regions of the United States for 1992, 1997, and 2002. Concentration and effluent flow data were examined for approximately 118,250 facilities in 45 states and the District of Columbia. Inconsistent and incomplete discharge locations, effluent flows, and effluent nutrient concentrations limited the use of these data for calculating nutrient loads. More concentrations were reported for major facilities, those discharging more than 1million gallons per day, than for minor facilities, and more concentrations were reported for TP than for TN. Analytical methods to check and improve the quality of the Permit Compliance System data were used. Annual loads were calculated using "typical pollutant concentrations" to supplement missing concentrations based on the type and size of facilities. Annual nutrient loads for over 26,600 facilities were calculated for at least one of the three years. Sewage systems represented 74% of all TN loads and 58% of all TP loads. This work represents an initial set of data to develop a comprehensive and consistent national database of point-source nutrient loads. These loads can be used to inform a wide range of water-quality management, watershed modeling, and research efforts at multiple scales. ?? 2011 American Water Resources Association. This article is a U.S. Government work and is in the public domain in the USA.
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Aerothermal Testing for Project Orion Crew Exploration Vehicle
NASA Technical Reports Server (NTRS)
Berry, Scott A.; Horvath, Thomas J.; Lillard, Randolph P.; Kirk, Benjamin S.; Fischer-Cassady, Amy
2009-01-01
The Project Orion Crew Exploration Vehicle aerothermodynamic experimentation strategy, as it relates to flight database development, is reviewed. Experimental data has been obtained to both validate the computational predictions utilized as part of the database and support the development of engineering models for issues not adequately addressed with computations. An outline is provided of the working groups formed to address the key deficiencies in data and knowledge for blunt reentry vehicles. The facilities utilized to address these deficiencies are reviewed, along with some of the important results obtained thus far. For smooth wall comparisons of computational convective heating predictions against experimental data from several facilities, confidence was gained with the use of algebraic turbulence model solutions as part of the database. For cavities and protuberances, experimental data is being used for screening various designs, plus providing support to the development of engineering models. With the reaction-control system testing, experimental data were acquired on the surface in combination with off-body flow visualization of the jet plumes and interactions. These results are being compared against predictions for improved understanding of aftbody thermal environments and uncertainties.
Malpractice Litigation and Nursing Home Quality of Care
Konetzka, R Tamara; Park, Jeongyoung; Ellis, Robert; Abbo, Elmer
2013-01-01
Objective. To assess the potential deterrent effect of nursing home litigation threat on nursing home quality. Data Sources/Study Setting. We use a panel dataset of litigation claims and Nursing Home Online Survey Certification and Reporting (OSCAR) data from 1995 to 2005 in six states: Florida, Illinois, Wisconsin, New Jersey, Missouri, and Delaware, for a total of 2,245 facilities. Claims data are from Westlaw's Adverse Filings database, a proprietary legal database, on all malpractice, negligence, and personal injury/wrongful death claims filed against nursing facilities. Study Design. A lagged 2-year moving average of the county-level number of malpractice claims is used to represent the threat of litigation. We use facility fixed-effects models to examine the relationship between the threat of litigation and nursing home quality. Principal Findings. We find significant increases in registered nurse-to-total staffing ratios in response to rising malpractice threat, and a reduction in pressure sores among highly staffed facilities. However, the magnitude of the deterrence effect is small. Conclusions. Deterrence in response to the threat of malpractice litigation is unlikely to lead to widespread improvements in nursing home quality. This should be weighed against other benefits and costs of litigation to assess the net benefit of tort reform. PMID:23741985
Children's (Pediatric) Abdominal Ultrasound Imaging
MedlinePlus Videos and Cool Tools
... Send us your feedback Did you find the information you were looking for? Yes No Please type ... facilities database . This website does not provide cost information. The costs for specific medical imaging tests, treatments ...
Monitoring SLAC High Performance UNIX Computing Systems
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lettsome, Annette K.; /Bethune-Cookman Coll. /SLAC
2005-12-15
Knowledge of the effectiveness and efficiency of computers is important when working with high performance systems. The monitoring of such systems is advantageous in order to foresee possible misfortunes or system failures. Ganglia is a software system designed for high performance computing systems to retrieve specific monitoring information. An alternative storage facility for Ganglia's collected data is needed since its default storage system, the round-robin database (RRD), struggles with data integrity. The creation of a script-driven MySQL database solves this dilemma. This paper describes the process took in the creation and implementation of the MySQL database for use by Ganglia.more » Comparisons between data storage by both databases are made using gnuplot and Ganglia's real-time graphical user interface.« less
WebCSD: the online portal to the Cambridge Structural Database
Thomas, Ian R.; Bruno, Ian J.; Cole, Jason C.; Macrae, Clare F.; Pidcock, Elna; Wood, Peter A.
2010-01-01
WebCSD, a new web-based application developed by the Cambridge Crystallographic Data Centre, offers fast searching of the Cambridge Structural Database using only a standard internet browser. Search facilities include two-dimensional substructure, molecular similarity, text/numeric and reduced cell searching. Text, chemical diagrams and three-dimensional structural information can all be studied in the results browser using the efficient entry summaries and embedded three-dimensional viewer. PMID:22477776
DOE Office of Scientific and Technical Information (OSTI.GOV)
Fox, G.C.; Stevens, P.R.; Rittenberg, A.
A compilation is presented of reaction data taken from experimental high energy physics journal articles, reports, preprints, theses, and other sources. Listings of all the data are given, and the data points are indexed by reaction and momentum, as well as by their source document. Much of the original compilation was done by others working in the field. The data presented also exist in the form of a computer-readable and searchable database; primitive access facilities for this database are available.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dehmel, J.C.; Loomis, D.; Mauro, J.
Under contract to the US Nuclear Regulatory Commission, Office of Nuclear Regulatory Research, the firms of S. Cohen & Associates, Inc. (SC&A) and Eastern Research Group (ERG) have compiled a report that describes the physical, chemical, and radiological properties of Class-A low-level radioactive waste. The report also presents information characterizing various methods and facilities used to treat and dispose non-radioactive waste. A database management program was developed for use in accessing, sorting, analyzing, and displaying the electronic data provided by EG&G. The program was used to present and aggregate data characterizing the radiological, physical, and chemical properties of the wastemore » from descriptions contained in shipping manifests. The data thus retrieved are summarized in tables, histograms, and cumulative distribution curves presenting radionuclide concentration distributions in Class-A waste as a function of waste streams, by category of waste generators, and regions of the United States. The report also provides information characterizing methods and facilities used to treat and dispose non-radioactive waste, including industrial, municipal, and hazardous waste regulated under Subparts C and D of the Resource Conservation and Recovery Act (RCRA). The information includes a list of disposal options, the geographical locations of the processing and disposal facilities, and a description of the characteristics of such processing and disposal facilities. Volume 1 contains the Executive Summary, Volume 2 presents the Class-A waste database, Volume 3 presents the information characterizing non-radioactive waste management practices and facilities, and Volumes 4 through 7 contain Appendices A through P with supporting information.« less
Design and development of a new facility for teaching and research in clinical anatomy.
Greene, John Richard T
2009-01-01
This article discusses factors in the design, commissioning, project management, and intellectual property protection of developments within a new clinical anatomy facility in the United Kingdom. The project was aimed at creating cost-effective facilities that would address widespread concerns over anatomy teaching, and support other activities central to the university mission-namely research and community interaction. The new facilities comprise an engaging learning environment and were designed to support a range of pedagogies appropriate to the needs of healthcare professionals at different stages of their careers. Specific innovations include integrated workstations each comprising of a dissection table, with removable top sections, an overhead operating light, and ceiling-mounted camera. The tables incorporate waterproof touch-screen monitors to display images from the camera, an endoscope or a database of images, videos, and tutorials. The screens work independently so that instructors can run different teaching sessions simultaneously and students can progress at different speeds to suit themselves. Further, database access is provided from within an integrated anatomy and pathology museum and display units dedicated to the correlation of cross-sectional anatomy with medical imaging. A new functional neuroanatomy modeling system, called the BrainTower, has been developed to aid integration of anatomy with physiology and clinical neurology. Many aspects of the new facility are reproduced within a Mobile Teaching Unit, which can be driven to hospitals, colleges, and schools to provide appropriate work-based education and community interaction. (c) 2009 American Association of Anatomists
Naumann, R Wendel; Brown, Jubilee
2015-01-01
To evaluate adverse events associated with electromechanical morcellation as reported to the Manufacturer and User Facility Device Experience (MAUDE) database. Retrospective analysis of an established database (Canadian Task Force classification III). A search of the MAUDE database for terms associated with commercially available electromechanical morcellation devices was undertaken for events leading to injury or death between 2004 and 2014. Data, including the types of injury, need for conversion to open surgery, type of open surgery, and clinical outcomes, were extracted from the records. Over a 10-year period, 9 events associated with death and 215 events associated with patient injury or significant delay of the surgical procedure were recorded. These involved 137 device failures, 51 organ injuries, and the morcellation of 27 previously undiagnosed malignancies. Of the 9 deaths, 1 was associated with organ injury, and the other 8 were associated with morcellation of cancer. Of the 27 undiagnosed cancers, 5 were reported by the manufacturer, 8 were reported by the patient or family, 9 were reported by medical or news reports, 2 were reported by medical professionals, and 3 were due to litigation. Morcellation of an undiagnosed malignancy was first reported to the database in December 2013. The MAUDE database appears to detect perioperative events, such as device failures and organ injury at the time of surgery, but appears to be poor at detecting late events after surgery, such as the potential spread of cancer. Outcome registries are likely a more efficient means of tracking potential long-term adverse events associated with surgical devices. Copyright © 2015 AAGL. Published by Elsevier Inc. All rights reserved.
Chen, Huan-Sheng; Cheng, Chun-Ting; Hou, Chun-Cheng; Liou, Hung-Hsiang; Chang, Cheng-Tsung; Lin, Chun-Ju; Wu, Tsai-Kun; Chen, Chang-Hsu; Lim, Paik-Seong
2017-07-01
Rapid screening and monitoring of nutritional status is mandatory in hemodialysis population because of the increasingly encountered nutritional problems. Considering the limitations of previous composite nutrition scores applied in this population, we tried to develop a standardized composite nutrition score (SCNS) using low lean tissue index as a marker of protein wasting to facilitate clinical screening and monitoring and to predict outcome. This retrospective cohort used 2 databases of dialysis populations from Taiwan between 2011 and 2014. First database consisting of data from 629 maintenance hemodialysis patients was used to develop the SCNS and the second database containing data from 297 maintenance hemodialysis patients was used to validate this developed score. SCNS containing albumin, creatinine, potassium, and body mass index was developed from the first database using low lean tissue index as a marker of protein wasting. When applying this score in the original database, significantly higher risk of developing protein wasting was found for patients with lower SCNS (odds ratio 1.38 [middle tertile vs highest tertile, P < .0001] and 2.40 [lowest tertile vs middle tertile, P < .0001]). The risk of death was also shown to be higher for patients with lower SCNS (hazard ratio 4.45 [below median level vs above median level, P < .0001]). These results were validated in the second database. We developed an SCNS consisting of 4 easily available biochemical parameters. This kind of scoring system can be easily applied in different dialysis facilities for screening and monitoring of protein wasting. The wide application of body composition monitor in dialysis population will also facilitate the development of specific nutrition scoring model for individual facility. Copyright © 2017 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.
National Transportation Atlas Databases : 1998
DOT National Transportation Integrated Search
1998-01-01
The North American Transportation Atlas Data - 1998 (NORTAD) is a set of : geographic data sets for transportation facilities in Canada, Mexico, and the United : States. These data sets include geospatial information for transportation modal networks...
An integrated knowledge system for wind tunnel testing - Project Engineers' Intelligent Assistant
NASA Technical Reports Server (NTRS)
Lo, Ching F.; Shi, George Z.; Hoyt, W. A.; Steinle, Frank W., Jr.
1993-01-01
The Project Engineers' Intelligent Assistant (PEIA) is an integrated knowledge system developed using artificial intelligence technology, including hypertext, expert systems, and dynamic user interfaces. This system integrates documents, engineering codes, databases, and knowledge from domain experts into an enriched hypermedia environment and was designed to assist project engineers in planning and conducting wind tunnel tests. PEIA is a modular system which consists of an intelligent user-interface, seven modules and an integrated tool facility. Hypermedia technology is discussed and the seven PEIA modules are described. System maintenance and updating is very easy due to the modular structure and the integrated tool facility provides user access to commercial software shells for documentation, reporting, or database updating. PEIA is expected to provide project engineers with technical information, increase efficiency and productivity, and provide a realistic tool for personnel training.
POLLUX: a program for simulated cloning, mutagenesis and database searching of DNA constructs.
Dayringer, H E; Sammons, S A
1991-04-01
Computer support for research in biotechnology has developed rapidly and has provided several tools to aid the researcher. This report describes the capabilities of new computer software developed in this laboratory to aid in the documentation and planning of experiments in molecular biology. The program, POLLUX, provides a graphical medium for the entry, edit and manipulation of DNA constructs and a textual format for display and edit of construct descriptive data. Program operation and procedures are designed to mimic the actual laboratory experiments with respect to capability and the order in which they are performed. Flexible control over the content of the computer-generated displays and program facilities is provided by a mouse-driven menu interface. Programmed facilities for mutagenesis, simulated cloning and searching of the database from networked workstations are described.
Indian Country Leaking Underground Storage Tanks, Region 9, 2016
This GIS dataset contains point features that represent Leaking Underground Storage Tanks in US EPA Region 9 Indian Country. This dataset contains facility name and locational information, status of LUST case, operating status of facility, inspection dates, and links to No Further Action letters for closed LUST cases. This database contains 1230 features, with 289 features having a LUST status of open, closed with no residual contamination, or closed with residual contamination.
Onshore industrial wind turbine locations for the United States
Diffendorfer, Jay E.; Compton, Roger; Kramer, Louisa; Ancona, Zach; Norton, Donna
2017-01-01
This dataset provides industrial-scale onshore wind turbine locations in the United States, corresponding facility information, and turbine technical specifications. The database has wind turbine records that have been collected, digitized, locationally verified, and internally quality controlled. Turbines from the Federal Aviation Administration Digital Obstacles File, through product release date July 22, 2013, were used as the primary source of turbine data points. The dataset was subsequently revised and reposted as described in the revision histories for the report. Verification of the turbine positions was done by visual interpretation using high-resolution aerial imagery in Environmental Systems Research Institute (Esri) ArcGIS Desktop. Turbines without Federal Aviation Administration Obstacles Repository System numbers were visually identified and point locations were added to the collection. We estimated a locational error of plus or minus 10 meters for turbine locations. Wind farm facility names were identified from publicly available facility datasets. Facility names were then used in a Web search of additional industry publications and press releases to attribute additional turbine information (such as manufacturer, model, and technical specifications of wind turbines). Wind farm facility location data from various wind and energy industry sources were used to search for and digitize turbines not in existing databases. Technical specifications for turbines were assigned based on the wind turbine make and model as described in literature, specifications listed in the Federal Aviation Administration Digital Obstacles File, and information on the turbine manufacturer’s Web site. Some facility and turbine information on make and model did not exist or was difficult to obtain. Thus, uncertainty may exist for certain turbine specifications. That uncertainty was rated and a confidence was recorded for both location and attribution data quality.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dionne, B.J.; Sullivan, S.G.; Baum, J.W.
1994-01-01
Promoting the exchange of information related to implementation of the As Low as Reasonably Achievable (ALARA) philosophy is a continuing objective for the Department of Energy (DOE). This report was prepared by the Brookhaven National Laboratory (BNL) ALARA Center for the DOE Office of Health. It contains the fifth in a series of bibliographies on dose reduction at DOE facilities. The BNL ALARA Center was originally established in 1983 under the sponsorship of the Nuclear Regulatory Commission to monitor dose-reduction research and ALARA activities at nuclear power plants. This effort was expanded in 1988 by the DOE`s Office of Environment,more » Safety and Health, to include DOE nuclear facilities. This bibliography contains abstracts relating to various aspects of ALARA program implementation and dose-reduction activities, with a specific focus on DOE facilities. Abstracts included in this bibliography were selected from proceedings of technical meetings, journals, research reports, searches of the DOE Energy, Science and Technology Database (in general, the citation and abstract information is presented as obtained from this database), and reprints of published articles provided by the authors. Facility types and activities covered in the scope of this report include: radioactive waste, uranium enrichment, fuel fabrication, spent fuel storage and reprocessing, facility decommissioning, hot laboratories, tritium production, research, test and production reactors, weapons fabrication and testing, fusion, uranium and plutonium processing, radiography, and accelerators. Information on improved shielding design, decontamination, containments, robotics, source prevention and control, job planning, improved operational and design techniques, as well as on other topics, has been included. In addition, DOE/EH reports not included in previous volumes of the bibliography are in this volume (abstracts 611 to 684). This volume (Volume 5 of the series) contains 217 abstracts.« less
Dexter, F; Epstein, R H; Dexter, E U; Lubarsky, D A; Sun, E C
2017-03-01
We considered whether senior hospital managers and department chairs need to be concerned that small reductions in average hospital length of stay (LOS) may be associated with greater rates of re-admission, use of home health care, and/or transfers to short-term care facilities. The 2013 United States Nationwide Readmissions Database was used to study surgical Diagnosis Related Groups (DRG) with 1) national median LOS ≥3 days and 2) ≥10 hospitals in the database that each had ≥100 discharges for the DRG. Dependent variables were considered individually: 1) re-admission within 30 days of discharge, 2) discharge disposition to home health care, and/or 3) discharge disposition of transfer to short-term care facility (i.e., inpatient rehabilitation hospital or skilled nursing facility). While controlling for DRG, each one-day decrease in hospital median LOS was associated with an odds of re-admission nationwide of 0.95 (95% confidence interval [CI] 0.92-0.99; P =0.012), odds of disposition upon discharge being home care of 0.95 (95% CI 0.83-1.10; P =0.64), and odds of transfer to short-term care facility of 0.68 (95% CI 0.54-0.85; P =0.0008). Results were insensitive to the addition of patient-specific data. In the USA, patients at hospitals with briefer median LOS across multiple common surgical procedures did not have a greater risk for either hospital re-admission within 30 days of discharge or transfer to an inpatient rehabilitation hospital or a skilled nursing facility. The generalisable implication is that, across many surgical procedures, DRG-based financial incentives to shorten hospital stays seem not to influence post-acute care decisions.
These reports show the backlog status nationwide, based on EPA databases and input from EPA regions and states. The reports show a snapshot in time, keep in mind that the status of facilities and the universe of permits change.
Monitoring of IaaS and scientific applications on the Cloud using the Elasticsearch ecosystem
NASA Astrophysics Data System (ADS)
Bagnasco, S.; Berzano, D.; Guarise, A.; Lusso, S.; Masera, M.; Vallero, S.
2015-05-01
The private Cloud at the Torino INFN computing centre offers IaaS services to different scientific computing applications. The infrastructure is managed with the OpenNebula cloud controller. The main stakeholders of the facility are a grid Tier-2 site for the ALICE collaboration at LHC, an interactive analysis facility for the same experiment and a grid Tier-2 site for the BES-III collaboration, plus an increasing number of other small tenants. Besides keeping track of the usage, the automation of dynamic allocation of resources to tenants requires detailed monitoring and accounting of the resource usage. As a first investigation towards this, we set up a monitoring system to inspect the site activities both in terms of IaaS and applications running on the hosted virtual instances. For this purpose we used the Elasticsearch, Logstash and Kibana stack. In the current implementation, the heterogeneous accounting information is fed to different MySQL databases and sent to Elasticsearch via a custom Logstash plugin. For the IaaS metering, we developed sensors for the OpenNebula API. The IaaS level information gathered through the API is sent to the MySQL database through an ad-hoc developed RESTful web service, which is also used for other accounting purposes. Concerning the application level, we used the Root plugin TProofMonSenderSQL to collect accounting data from the interactive analysis facility. The BES-III virtual instances used to be monitored with Zabbix, as a proof of concept we also retrieve the information contained in the Zabbix database. Each of these three cases is indexed separately in Elasticsearch. We are now starting to consider dismissing the intermediate level provided by the SQL database and evaluating a NoSQL option as a unique central database for all the monitoring information. We setup a set of Kibana dashboards with pre-defined queries in order to monitor the relevant information in each case. In this way we have achieved a uniform monitoring interface for both the IaaS and the scientific applications, mostly leveraging off-the-shelf tools.
NetIntel: A Database for Manipulation of Rich Social Network Data
2005-03-03
between entities in a social or organizational system. For most of its history , social network analysis has operated on a notion of a dataset - a clearly...and procedural), as well as stored procedure and trigger capabilities. For the current implementation, we have chosen PostgreSQL [1] database. Of the...data and easy-to-use facilities for export of data into analysis tools as well as online browsing and data entry. References [1] Postgresql
LDEF meteoroid and debris database
NASA Technical Reports Server (NTRS)
Dardano, C. B.; See, Thomas H.; Zolensky, Michael E.
1994-01-01
The Long Duration Exposure Facility (LDEF) Meteoroid and Debris Special Investigation Group (M&D SIG) database is maintained at the Johnson Space Center (JSC), Houston, Texas, and consists of five data tables containing information about individual features, digitized images of selected features, and LDEF hardware (i.e., approximately 950 samples) archived at JSC. About 4000 penetrations (greater than 300 micron in diameter) and craters (greater than 500 micron in diameter) were identified and photodocumented during the disassembly of LDEF at the Kennedy Space Center (KSC), while an additional 4500 or so have subsequently been characterized at JSC. The database also contains some data that have been submitted by various PI's, yet the amount of such data is extremely limited in its extent, and investigators are encouraged to submit any and all M&D-type data to JSC for inclusion within the M&D database. Digitized stereo-image pairs are available for approximately 4500 features through the database.
Notre Dame Nuclear Database: A New Chart of Nuclides
NASA Astrophysics Data System (ADS)
Lee, Kevin; Khouw, Timothy; Fasano, Patrick; Mumpower, Matthew; Aprahamian, Ani
2014-09-01
Nuclear data is critical to research fields from medicine to astrophysics. We are creating a database, the Notre Dame Nuclear Database, which can store theoretical and experimental datasets. We place emphasis on storing metadata and user interaction with the database. Users are able to search in addition to the specific nuclear datum, the author(s), the facility where the measurements were made, the institution of the facility, and device or method/technique used. We also allow users to interact with the database by providing online search, an interactive nuclide chart, and a command line interface. The nuclide chart is a more descriptive version of the periodic table that can be used to visualize nuclear properties such as half-lives and mass. We achieve this by using D3 (Data Driven Documents), HTML, and CSS3 to plot the nuclides and color them accordingly. Search capabilities can be applied dynamically to the chart by using Python to communicate with MySQL, allowing for customization. Users can save the customized chart they create to any image format. These features provide a unique approach for researchers to interface with nuclear data. We report on the current progress of this project and will present a working demo that highlights each aspect of the aforementioned features. This is the first time that all available technologies are put to use to make nuclear data more accessible than ever before in a manner that is much easier and fully detailed. This is a first and we will make it available as open source ware.
Space Station Freedom environmental database system (FEDS) for MSFC testing
NASA Technical Reports Server (NTRS)
Story, Gail S.; Williams, Wendy; Chiu, Charles
1991-01-01
The Water Recovery Test (WRT) at Marshall Space Flight Center (MSFC) is the first demonstration of integrated water recovery systems for potable and hygiene water reuse as envisioned for Space Station Freedom (SSF). In order to satisfy the safety and health requirements placed on the SSF program and facilitate test data assessment, an extensive laboratory analysis database was established to provide a central archive and data retrieval function. The database is required to store analysis results for physical, chemical, and microbial parameters measured from water, air and surface samples collected at various locations throughout the test facility. The Oracle Relational Database Management System (RDBMS) was utilized to implement a secured on-line information system with the ECLSS WRT program as the foundation for this system. The database is supported on a VAX/VMS 8810 series mainframe and is accessible from the Marshall Information Network System (MINS). This paper summarizes the database requirements, system design, interfaces, and future enhancements.
Owens, John
2009-01-01
Technological advances in the acquisition of DNA and protein sequence information and the resulting onrush of data can quickly overwhelm the scientist unprepared for the volume of information that must be evaluated and carefully dissected to discover its significance. Few laboratories have the luxury of dedicated personnel to organize, analyze, or consistently record a mix of arriving sequence data. A methodology based on a modern relational-database manager is presented that is both a natural storage vessel for antibody sequence information and a conduit for organizing and exploring sequence data and accompanying annotation text. The expertise necessary to implement such a plan is equal to that required by electronic word processors or spreadsheet applications. Antibody sequence projects maintained as independent databases are selectively unified by the relational-database manager into larger database families that contribute to local analyses, reports, interactive HTML pages, or exported to facilities dedicated to sophisticated sequence analysis techniques. Database files are transposable among current versions of Microsoft, Macintosh, and UNIX operating systems.
Pokorná, Andrea; Benešová, Klára; Jarkovský, Jirˇí; Mužík, Jan; Beeckman, Dimitri
The purpose of this study was to analyze pressure injury (PI) occurrence upon admission and at any time during the hospital course inpatients care facilities in the Czech Republic. Secondary aims were to evaluate demographic and clinical data of patients with PI and the impact of a PI on length of stay (LOS) in the hospital. Retrospective, cross-sectional analysis. The sample comprised data of hospitalized patients entered into the National Register of Hospitalized Patients (NRHOSP) database of the Czech Republic between 2007 and 2014 with a diagnosis L89 (pressure ulcer of unspecified site based on the International Classification of Diseases, Tenth Revision, ICD-10). Electronic records of 17,762,854 hospitalizations were reviewed. Data from the NRHOSP from all acute and non-acute care hospitals in the Czech Republic were analyzed. Specifically, we analyzed patients admitted to acute and non-acute care facilities with a primary or secondary diagnosis of PI. The NRHOSP database included 17,762,854 cases, of which 46,224 cases (33,342 cases in acute care hospitals; 12,882 in non-acute care hospitals) had the L89 diagnosis (0.3%). The mean age of patients admitted with a PI was 73.8 ± 15.3 years (mean ± SD), and their average LOS was 33.2 ± 76.9 days. The mean LOS of patients hospitalized with L89 code as a primary diagnosis (n = 6877) was significantly longer compared to those patients for whom L89 code was a secondary diagnosis (25.8 vs 20.2 days, P < .001) in acute care facilities. In contrast, we found no difference in the mean LOS for patients hospitalized in non-acute care facility (58.7 days vs 65.1 days; P = .146) with ICD code L89. Pressure injuries were associated with significant LOS in both acute and non-acute care settings in the Czech Republic. Despite the valuable insights we obtained from the analysis of NRHOSP data, we advocate creation of a more valid and reliable electronic reporting system that enables policy makers to evaluate the quality and safety concerning PI and its impact on patients and the healthcare system.
A Study of Airbase Facility/Utility Energy R and D Requirements
1992-04-01
facility/utility energy requirements for system implementations, modifications, or deletions were collected, entered into the database, and compared with...BASE_________ ENERGY LOS1 %) 200 MBtu TOTAL COSTS 100 Motu ELECTRIC 100 Motu THERMAL337 Motu ,, OF1FUEL 100 MBtu OF(10 11 PURCHASED S 1800.00 ELECTRIC...this page. Usage Data = *.BTU I. Correct spelling of Base name and Command 2. Macro does the following: Inserts or deletes columns or rows so that D4
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dionne, B.J.; Sullivan, S.G.; Baum, J.W.
1993-12-01
This bibliography contains abstracts relating to various aspects of ALARA program implementation and dose reduction activities, with a focus on DOE facilities. Abstracts included in this bibliography were selected from proceedings of technical meetings, journals, research reports, searches of the DOE Energy, Science and Technology Database (in general, the citation and abstract information is presented as obtained from this database), and reprints of published articles provided by the authors. Facility types and activities covered in the scope of this report include: radioactive waste, uranium enrichment, fuel fabrication, spent fuel storage and reprocessing, facility decommissioning, hot laboratories, tritium production, research, testmore » and production reactors, weapons fabrication and testing, fusion, uranium and plutonium processing, radiography, and aocelerators. Information on improved shielding design, decontamination, containments, robotics, source prevention and control, job planning, improved operational and design techniques, as well as on other topics, has been included. In addition, DOE/EH reports not included in previous volumes of the bibliography are in this volume (abstracts 611 to 684). This volume (Volume 5 of the series) contains 217 abstracts. An author index and a subject index are provided to facilitate use. Both indices contain the abstract numbers from previous volumes, as well as the current volume. Information that the reader feels might be included in the next volume of this bibliography should be submitted to the BNL ALARA Center.« less
Adopting a corporate perspective on databases. Improving support for research and decision making.
Meistrell, M; Schlehuber, C
1996-03-01
The Veterans Health Administration (VHA) is at the forefront of designing and managing health care information systems that accommodate the needs of clinicians, researchers, and administrators at all levels. Rather than using one single-site, centralized corporate database VHA has constructed several large databases with different configurations to meet the needs of users with different perspectives. The largest VHA database is the Decentralized Hospital Computer Program (DHCP), a multisite, distributed data system that uses decoupled hospital databases. The centralization of DHCP policy has promoted data coherence, whereas the decentralization of DHCP management has permitted system development to be done with maximum relevance to the users'local practices. A more recently developed VHA data system, the Event Driven Reporting system (EDR), uses multiple, highly coupled databases to provide workload data at facility, regional, and national levels. The EDR automatically posts a subset of DHCP data to local and national VHA management. The development of the EDR illustrates how adoption of a corporate perspective can offer significant database improvements at reasonable cost and with modest impact on the legacy system.
Systematic Review of Multidisciplinary Chronic Pain Treatment Facilities
Fashler, Samantha R.; Cooper, Lynn K.; Oosenbrug, Eric D.; Burns, Lindsay C.; Razavi, Shima; Goldberg, Lauren; Katz, Joel
2016-01-01
This study reviewed the published literature evaluating multidisciplinary chronic pain treatment facilities to provide an overview of their availability, caseload, wait times, and facility characteristics. A systematic literature review was conducted using PRISMA guidelines following a search of MEDLINE, PsycINFO, and CINAHL databases. Inclusion criteria stipulated that studies be original research, survey more than one pain treatment facility directly, and describe a range of available treatments. Fourteen articles satisfied inclusion criteria. Results showed little consistency in the research design used to describe pain treatment facilities. Availability of pain treatment facilities was scarce and the reported caseloads and wait times were generally high. A wide range of medical, physical, and psychological pain treatments were available. Most studies reported findings on the percentage of practitioners in different health care professions employed. Future studies should consider using more comprehensive search strategies to survey facilities, improving clarity on what is considered to be a pain treatment facility, and reporting on a consistent set of variables to provide a clear summary of the status of pain treatment facilities. This review highlights important information for policymakers on the scope, demand, and accessibility of pain treatment facilities. PMID:27445618
Fuel conditioning facility zone-to-zone transfer administrative controls.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pope, C. L.
2000-06-21
The administrative controls associated with transferring containers from one criticality hazard control zone to another in the Argonne National Laboratory (ANL) Fuel Conditioning Facility (FCF) are described. FCF, located at the ANL-West site near Idaho Falls, Idaho, is used to remotely process spent sodium bonded metallic fuel for disposition. The process involves nearly forty widely varying material forms and types, over fifty specific use container types, and over thirty distinct zones where work activities occur. During 1999, over five thousand transfers from one zone to another were conducted. Limits are placed on mass, material form and type, and container typesmore » for each zone. Ml material and containers are tracked using the Mass Tracking System (MTG). The MTG uses an Oracle database and numerous applications to manage the database. The database stores information specific to the process, including material composition and mass, container identification number and mass, transfer history, and the operators involved in each transfer. The process is controlled using written procedures which specify the zone, containers, and material involved in a task. Transferring a container from one zone to another is called a zone-to-zone transfer (ZZT). ZZTs consist of four distinct phases, select, request, identify, and completion.« less
Shah, Sachin D.; Quigley, Sean M.
2005-01-01
Air Force Plant 4 (AFP4) and adjacent Naval Air Station-Joint Reserve Base (NAS-JRB) at Fort Worth, Tex., constitute a government-owned, contractor-operated (GOCO) facility that has been in operation since 1942. Contaminants from the facility, primarily volatile organic compounds (VOCs) and metals, have entered the groundwater-flow system through leakage from waste-disposal sites (landfills and pits) and from manufacturing processes (U.S. Air Force, Aeronautical Systems Center, 1995). The U.S. Geological Survey (USGS), in cooperation with the U.S. Air Force (USAF), Aeronautical Systems Center, Environmental Management Directorate (ASC/ENVR), developed a comprehensive database (or geodatabase) of temporal and spatial environmental information associated with the geology, hydrology, and water quality at AFP4 and NAS-JRB. The database of this report provides information about the AFP4 and NAS-JRB study area including sample location names, identification numbers, locations, historical dates, and various measured hydrologic data. This database does not include every sample location at the site, but is limited to an aggregation of selected digital and hardcopy data of the USAF, USGS, and various consultants who have previously or are currently working at the site.
DOE Office of Scientific and Technical Information (OSTI.GOV)
McHugh, M.G.; Coleman, G.H.
2006-07-01
The contents of a safety basis (SB) are based upon the facility's purpose of operation, radiological inventory, and safety systems in place to mitigate any releases to the employees, general public and environment. Specifically, the radiological inventory is used for facility categorizations (e.g., Category 2, Category 3) and determining the material at risk used in the associated nuclear safety analysis calculations. Radiological inventory discrepancies, referred to as 'mismatches', have the potential to adversely impact the SB. This paper summarizes a process developed to: 1) identify these 'mismatches' based on a facility's radiological inventory, 2) categorize these 'mismatches' according to availablemore » data, and then 3) determine if these 'mismatches' yield either trivial or significant cumulative impacts on credited assumptions associated with a particular facility's SB. The two facilities evaluated for 'mismatches' were the K-1065 Complex and the Above Grade Storage Facility (AGSF). The randomly selected containers from each facility were obtained along with screening the radiological inventories found in the Waste Information Tracking System (WITS) database and the Request for Disposal (RFD) forms. Ideally, the radiological inventory, which is comprised of isotopic data for each container, is maintained in the WITS database. However, the RFD is the official repository record for isotopic data for each container. Historically, neither WITS nor the RFDs were required to contain isotopic data. Based on the WITS and RFD data, the containers were then categorized into five (5) separate conditions: Condition 1) Isotopic data in the RFD matches the isotopic data in WITS; Condition 2) Isotopic data in the RFD does not match the isotopic data in WITS; Condition 3) Isotopic data are in the RFD, but are not in WITS; Condition 4) No isotopic data in the RFD, but isotopic data are found in WITS; Condition 5) No isotopic data found in either the RFD or WITS. The results show trivial cumulative impacts (i.e., no inherent data biases) on credited assumptions associated with the K-1065 Complex and AGSF SBs. Recent random comparisons of WITS and RFDs continue to verify and validate that the administrative and procedural controls are adequate to ensure compliance with the SB for these facilities, thus providing a useful model for evaluating other facilities located at the Department of Energy's Oak Ridge Reservation (DOE-ORR). (authors)« less
Characterization of Class A low-level radioactive waste 1986--1990. Volume 6: Appendices G--J
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dehmel, J.C.; Loomis, D.; Mauro, J.
1994-01-01
Under contract to the US Nuclear Regulatory Commission, Office of Nuclear Regulatory Research, the firms of S. Cohen & Associates, Inc. (SC&A) and Eastern Research Group (ERG) have compiled a report that describes the physical, chemical, and radiological properties of Class-A low-level radioactive waste. The report also presents information characterizing various methods and facilities used to treat and dispose non-radioactive waste. A database management program was developed for use in accessing, sorting, analyzing, and displaying the electronic data provided by EG&G. The program was used to present and aggregate data characterizing the radiological, physical, and chemical properties of the wastemore » from descriptions contained in shipping manifests. The data thus retrieved are summarized in tables, histograms, and cumulative distribution curves presenting radionuclide concentration distributions in Class-A waste as a function of waste streams, by category of waste generators, and regions of the United States. The report also provides information characterizing methods and facilities used to treat and dispose non-radioactive waste, including industrial, municipal, and hazardous waste regulated under Subparts C and D of the Resource Conservation and Recovery Act (RCRA). The information includes a list of disposal options, the geographical locations of the processing and disposal facilities, and a description of the characteristics of such processing and disposal facilities. Volume 1 contains the Executive Summary, Volume 2 presents the Class-A waste database, Volume 3 presents the information characterizing non-radioactive waste management practices and facilities, and Volumes 4 through 7 contain Appendices A through P with supporting information.« less
Kleindorfer, Paul R; Belke, James C; Elliott, Michael R; Lee, Kiwan; Lowe, Robert A; Feldman, Harold I
2003-10-01
This article reports on the data collected on one of the most ambitious government-sponsored environmental data acquisition projects of all time, the Risk Management Plan (RMP) data collected under section 112(r) of the Clean Air Act Amendments of 1990. This RMP Rule 112(r) was triggered by the Bhopal accident in 1984 and led to the requirement that each qualifying facility develop and file with the U.S. Environmental Protection Agency a Risk Management Plan (RMP) as well as accident history data for the five-year period preceding the filing of the RMP. These data were collected in 1999-2001 on more than 15,000 facilities in the United States that store or use listed toxic or flammable chemicals believed to be a hazard to the environment or to human health of facility employees or off-site residents of host communities. The resulting database, RMP*Info, has become a key resource for regulators and researchers concerned with the frequency and severity of accidents, and the underlying facility-specific factors that are statistically associated with accident and injury rates. This article analyzes which facilities actually filed under the Rule and presents results on accident frequencies and severities available from the RMP*Info database. This article also presents summaries of related results from RMP*Info on Offsite Consequence Analysis (OCA), an analytical estimate of the potential consequences of hypothetical worst-case and alternative accidental releases on the public and environment around the facility. The OCA data have become a key input in the evaluation of site security assessment and mitigation policies for both government planners as well as facility managers and their insurers. Following the survey of the RMP*Info data, we discuss the rich set of policy decisions that may be informed by research based on these data.
Remand Order - Pennsauken County, New Jersey Recovery Facility
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Deficient Permit Notification Notice For Lake County Waste to Energy Facility
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Remand -- Honolulu Resource Recovery Facility, Applicant
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Determining PSD Applicability Thresholds for Gas Turbine Based Facilities
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Administrative Order -- Lake County Waste To Energy Facility Okahumpka, Florida
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
PSD Source Classification for Safety Kleen's Lubricating Oil Recovery Facility
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
BP American Production Company's Florida River Compression Facility Single Source Determination
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
CO BACT at the Propose Sithe Energy Heritage Generating Facility
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Is a Solvent Reclamation Facility Considered a Chemical Process Plant
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
American Soda.. Multi-facility Source Determination
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Reactivation of Amerada Hess Corporation's Port Reading Facility and PSD Review
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Guidance on PSD Applicability for Refuse-to-Energy Facilities
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
St. Lawrence Cement... Two Facilities or One?
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Support Facility Determination... Oscar Mayer and Madison Gas and Electric
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Analysis of NASA Common Research Model Dynamic Data
NASA Technical Reports Server (NTRS)
Balakrishna, S.; Acheson, Michael J.
2011-01-01
Recent NASA Common Research Model (CRM) tests at the Langley National Transonic Facility (NTF) and Ames 11-foot Transonic Wind Tunnel (11-foot TWT) have generated an experimental database for CFD code validation. The database consists of force and moment, surface pressures and wideband wing-root dynamic strain/wing Kulite data from continuous sweep pitch polars. The dynamic data sets, acquired at 12,800 Hz sampling rate, are analyzed in this study to evaluate CRM wing buffet onset and potential CRM wing flow separation.
Expediting the Process of a PSD for a Power-Generating Facility
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Calvert City Power Combustion Turbine Facility
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Saunders, Rebecca E; Instrell, Rachael; Rispoli, Rossella; Jiang, Ming; Howell, Michael
2013-01-01
High-throughput screening (HTS) uses technologies such as RNA interference to generate loss-of-function phenotypes on a genomic scale. As these technologies become more popular, many research institutes have established core facilities of expertise to deal with the challenges of large-scale HTS experiments. As the efforts of core facility screening projects come to fruition, focus has shifted towards managing the results of these experiments and making them available in a useful format that can be further mined for phenotypic discovery. The HTS-DB database provides a public view of data from screening projects undertaken by the HTS core facility at the CRUK London Research Institute. All projects and screens are described with comprehensive assay protocols, and datasets are provided with complete descriptions of analysis techniques. This format allows users to browse and search data from large-scale studies in an informative and intuitive way. It also provides a repository for additional measurements obtained from screens that were not the focus of the project, such as cell viability, and groups these data so that it can provide a gene-centric summary across several different cell lines and conditions. All datasets from our screens that can be made available can be viewed interactively and mined for further hit lists. We believe that in this format, the database provides researchers with rapid access to results of large-scale experiments that might facilitate their understanding of genes/compounds identified in their own research. DATABASE URL: http://hts.cancerresearchuk.org/db/public.
Use of the Decision Support System for VA cost-effectiveness research.
Barnett, P G; Rodgers, J H
1999-04-01
The Department of Veterans Affairs is adopting the Decision Support System (DSS), computer software and databases which include a cost-accounting system which determines the cost of health care products and patient encounters. A system for providing cost data for cost-effectiveness analysis should be provide valid, detailed, and comprehensive data that can be aggregated. The design of DSS is described and compared with those criteria. Utilization data from DSS was compared with other VA utilization data. Aggregate DSS cost data from 35 medical centers was compared with relative resource weights developed for the Medicare program. Data on hospital stays at 3 facilities found that 3.7% of the stays in DSS were not in the VA discharge database, whereas 7.6% of the stays in the discharge data were not in DSS. DSS reported between 68.8% and 97.1% of the outpatient encounters reported by six facilities in the ambulatory care data base. Relative weights for each Diagnosis Related Group based on DSS data from 35 VA facilities correlated with Medicare weights (correlation coefficient of .853). DSS will be useful for research if certain problems are overcome. It is difficult to distinguish long-term from acute hospital care. VA does not have a complete database of all inpatient procedures, so DSS has not assigned them a specific cost. The authority to access encounter-level DSS data needs to be centralized. Researchers can provide the feedback needed to improve DSS cost estimates. A comprehensive encounter-level extract would facilitate use of DSS for research.
Simons, Kelsey V
2006-11-01
This research sought to identify organizational characteristics associated with the amount of professional qualifications among a nationally representative sample of nursing home social service directors. A self-administered survey was sent to directors in 675 facilities randomly sampled from a federal database, excluding facilities with fewer than 120 beds that are not required to staff a full-time social worker. The response rate was 45 percent (N = 299). Univariate results showed that most respondents possessed a social work degree, most lacked licensure, and few were clinically supervised. A multiple regression analysis found that nonprofit, independently owned facilities in rural areas staffed social service directors who were significantly more qualified than directors in for-profit, chain-affiliated facilities in urban and suburban areas. Facilities with fewer psychosocial deficiencies and higher occupancy rates employed social service directors with greater qualifications. The implications of these findings for social work education, practice, policy, and research are discussed.
The Imaging X-Ray Polarimetry Explorer (IXPE): Overview
NASA Technical Reports Server (NTRS)
O'Dell, Steve; Weisskopf, M.; Soffitta, P.; Baldini, L.; Bellazzini, R.; Costa, E.; Elsner, R.; Kaspi, V.; Kolodziejczak, J.; Latronico, L.;
2017-01-01
Mission background: Imaging x-ray polarimetry in 2–8 kiloelectronvolt band; NASA Astrophysics Small Explorer (SMEX) selected in 2017 January. Orbit: Pegasus-XL (airborne) launch in 2021, from Kwajalein; Equatorial circular orbit at greater than or approximately equal to 540 kilometers (620 kilometers, goal) altitude. Flight system: Spacecraft, payload structure, and integration by Ball Aerospace - Deployable payload boom from Orbital-ATK, under contract to Ball; X-ray Mirror Module Assemblies by NASA/MSFC; X-ray (polarization-sensitive) Instruments by IAPS/INAF (Istituto di Astrofisica e Planetologia Spaziali / Istituto Nazionale di Astrofisica) and INFN (Istituto Nazionale di Fisica Nucleare). Ground system: ASI (Agenzia Spaziale Italiana) Malindi ground station, with Singapore backup; Mission Operations Center at LASP (Laboratory for Atmospheric and Space Physics, University of Colorado); Science Operations Center at NASA/MSFC; Data archive at HEASARC (High Energy Astrophysics Science Archive Research Center), (NASA/GSFC), mirror at ASI Data Center. Science: Active galactic nuclei; Microquasars; Radio pulsars and pulsar wind nebulae; Supernova remnants; Magnetars; Accreting x-ray pulsars.
Joshi, Kshamta; Billick, Stephen Bates
2017-03-01
To identify various biopsychosocial risk factors associated with suicidality in juvenile detention facilities and the effectiveness of suicide prevention protocols currently in use. Medical literature searches were conducted using databases like Pub Med, Ovid, and Google Scholar to identify studies conducted in and outside of United States. The prevalence of suicide among youth imprisoned at detention facilities has risen. Psychiatric disorders are common among such population, making them vulnerable to suicidal tendencies. Suicide risk screening within first 24 h of admission to the detention facility has shown to lower the risk of suicide. Identification of high risk individuals and their further psychiatric assessment is advocated. Much of work with regards to screening tools and instruments is underway and further study is required to get a better understanding.
The Defense Technical Information Center (DTIC?) is the central facility for the collection and dissemination of scientific and technical information for the Department of Defense (DoD). Much of this information is made available by DTIC in the form of technical reports about com...
Estimates of Urban Roadway Congestion, 1990: Interim Report
DOT National Transportation Integrated Search
1993-03-01
This research report is the fifth year continuation of a six year research effort focused on quantifying urban mobility. This study contains the facility information for 50 urban areas throughout the country. The database used for this research conta...
GAS CHROMATOGRAPHIC RETENTION PARAMETERS DATABASE FOR REFRIGERANT MIXTURE COMPOSITION MANAGEMENT
Composition management of mixed refrigerant systems is a challenging problem in the laboratory, manufacturing facilities, and large refrigeration machinery. Ths issue of composition management is especially critical for the maintenance of machinery that utilizes zeotropic mixture...
Real Property Survey, Federal Prison Camp Nellis, Las Vegas, Nevada
1999-01-26
Release Frequency: Semi-Annually Uranium ore was mined by private companies for federal government use in national defense programs. When the mills...databases: FEDERA.L ASTM STANDARD NPL •••••.••.•. ---·--------- National Priority List Proposed NPL _ •••••••. •.. . . Proposed National Priority... National Priority List Deletions FINDS •• •••••••.. -----·-···-- Facility Index System/Facility Registry System HMIRS
The aerospace energy systems laboratory: Hardware and software implementation
NASA Technical Reports Server (NTRS)
Glover, Richard D.; Oneil-Rood, Nora
1989-01-01
For many years NASA Ames Research Center, Dryden Flight Research Facility has employed automation in the servicing of flight critical aircraft batteries. Recently a major upgrade to Dryden's computerized Battery Systems Laboratory was initiated to incorporate distributed processing and a centralized database. The new facility, called the Aerospace Energy Systems Laboratory (AESL), is being mechanized with iAPX86 and iAPX286 hardware running iRMX86. The hardware configuration and software structure for the AESL are described.
EPA Facility Registry Service (FRS): PCS_NPDES
This web feature service contains location and facility identification information from EPA's Facility Registry Service (FRS) for the subset of facilities that link to the Permit Compliance System (PCS) or the National Pollutant Discharge Elimination System (NPDES) module of the Integrated Compliance Information System (ICIS). PCS tracks NPDES surface water permits issued under the Clean Water Act. This system is being incrementally replaced by the NPDES module of ICIS. Under NPDES, all facilities that discharge pollutants from any point source into waters of the United States are required to obtain a permit. The permit will likely contain limits on what can be discharged, impose monitoring and reporting requirements, and include other provisions to ensure that the discharge does not adversely affect water quality. FRS identifies and geospatially locates facilities, sites or places subject to environmental regulations or of environmental interest. Using vigorous verification and data management procedures, FRS integrates facility data from EPA's national program systems, other federal agencies, and State and tribal master facility records and provides EPA with a centrally managed, single source of comprehensive and authoritative information on facilities. This data set contains the subset of FRS integrated facilities that link to NPDES facilities once the PCS or ICIS-NPDES data has been integrated into the FRS database. Additional information on FRS is available
Reference Material Kydex(registered trademark)-100 Test Data Message for Flammability Testing
NASA Technical Reports Server (NTRS)
Engel, Carl D.; Richardson, Erin; Davis, Eddie
2003-01-01
The Marshall Space Flight Center (MSFC) Materials and Processes Technical Information System (MAPTIS) database contains, as an engineering resource, a large amount of material test data carefully obtained and recorded over a number of years. Flammability test data obtained using Test 1 of NASA-STD-6001 is a significant component of this database. NASA-STD-6001 recommends that Kydex 100 be used as a reference material for testing certification and for comparison between test facilities in the round-robin certification testing that occurs every 2 years. As a result of these regular activities, a large volume of test data is recorded within the MAPTIS database. The activity described in this technical report was undertaken to mine the database, recover flammability (Test 1) Kydex 100 data, and review the lessons learned from analysis of these data.
Migration from relational to NoSQL database
NASA Astrophysics Data System (ADS)
Ghotiya, Sunita; Mandal, Juhi; Kandasamy, Saravanakumar
2017-11-01
Data generated by various real time applications, social networking sites and sensor devices is of very huge amount and unstructured, which makes it difficult for Relational database management systems to handle the data. Data is very precious component of any application and needs to be analysed after arranging it in some structure. Relational databases are only able to deal with structured data, so there is need of NoSQL Database management System which can deal with semi -structured data also. Relational database provides the easiest way to manage the data but as the use of NoSQL is increasing it is becoming necessary to migrate the data from Relational to NoSQL databases. Various frameworks has been proposed previously which provides mechanisms for migration of data stored at warehouses in SQL, middle layer solutions which can provide facility of data to be stored in NoSQL databases to handle data which is not structured. This paper provides a literature review of some of the recent approaches proposed by various researchers to migrate data from relational to NoSQL databases. Some researchers proposed mechanisms for the co-existence of NoSQL and Relational databases together. This paper provides a summary of mechanisms which can be used for mapping data stored in Relational databases to NoSQL databases. Various techniques for data transformation and middle layer solutions are summarised in the paper.
REFGEN and TREENAMER: Automated Sequence Data Handling for Phylogenetic Analysis in the Genomic Era
Leonard, Guy; Stevens, Jamie R.; Richards, Thomas A.
2009-01-01
The phylogenetic analysis of nucleotide sequences and increasingly that of amino acid sequences is used to address a number of biological questions. Access to extensive datasets, including numerous genome projects, means that standard phylogenetic analyses can include many hundreds of sequences. Unfortunately, most phylogenetic analysis programs do not tolerate the sequence naming conventions of genome databases. Managing large numbers of sequences and standardizing sequence labels for use in phylogenetic analysis programs can be a time consuming and laborious task. Here we report the availability of an online resource for the management of gene sequences recovered from public access genome databases such as GenBank. These web utilities include the facility for renaming every sequence in a FASTA alignment file, with each sequence label derived from a user-defined combination of the species name and/or database accession number. This facility enables the user to keep track of the branching order of the sequences/taxa during multiple tree calculations and re-optimisations. Post phylogenetic analysis, these webpages can then be used to rename every label in the subsequent tree files (with a user-defined combination of species name and/or database accession number). Together these programs drastically reduce the time required for managing sequence alignments and labelling phylogenetic figures. Additional features of our platform include the automatic removal of identical accession numbers (recorded in the report file) and generation of species and accession number lists for use in supplementary materials or figure legends. PMID:19812722
Weiss, Lizabeth M; Drake, Audrey
2007-01-01
An electronic database was developed for succession planning and placement of nursing leaders interested and ready, willing, and able to accept an assignment in a nursing leadership position. The tool is a 1-page form used to identify candidates for nursing leadership assignments. This tool has been deployed nationally, with access to the database restricted to nurse executives at every Veterans Health Administration facility for the purpose of entering the names of developed nurse leaders ready for a leadership assignment. The tool is easily accessed through the Veterans Health Administration Office of Nursing Service, and by limiting access to the nurse executive group, ensures candidates identified are qualified. Demographic information included on the survey tool includes the candidate's demographic information and other certifications/credentials. This completed information form is entered into a database from which a report can be generated, resulting in a listing of potential candidates to contact to supplement a local or Veterans Integrated Service Network wide position announcement. The data forms can be sorted by positions, areas of clinical or functional experience, training programs completed, and geographic preference. The forms can be edited or updated and/or added or deleted in the system as the need is identified. This tool allows facilities with limited internal candidates to have a resource with Department of Veterans Affairs prepared staff in which to seek additional candidates. It also provides a way for interested candidates to be considered for positions outside of their local geographic area.
McIlroy, Simon Jon; Kirkegaard, Rasmus Hansen; McIlroy, Bianca; Nierychlo, Marta; Kristensen, Jannie Munk; Karst, Søren Michael; Albertsen, Mads; Nielsen, Per Halkjær
2017-01-01
Wastewater is increasingly viewed as a resource, with anaerobic digester technology being routinely implemented for biogas production. Characterising the microbial communities involved in wastewater treatment facilities and their anaerobic digesters is considered key to their optimal design and operation. Amplicon sequencing of the 16S rRNA gene allows high-throughput monitoring of these systems. The MiDAS field guide is a public resource providing amplicon sequencing protocols and an ecosystem-specific taxonomic database optimized for use with wastewater treatment facility samples. The curated taxonomy endeavours to provide a genus-level-classification for abundant phylotypes and the online field guide links this identity to published information regarding their ecology, function and distribution. This article describes the expansion of the database resources to cover the organisms of the anaerobic digester systems fed primary sludge and surplus activated sludge. The updated database includes descriptions of the abundant genus-level-taxa in influent wastewater, activated sludge and anaerobic digesters. Abundance information is also included to allow assessment of the role of emigration in the ecology of each phylotype. MiDAS is intended as a collaborative resource for the progression of research into the ecology of wastewater treatment, by providing a public repository for knowledge that is accessible to all interested in these biotechnologically important systems. http://www.midasfieldguide.org. © The Author(s) 2017. Published by Oxford University Press.
The Vendors' Corner: Biblio-Techniques' Library and Information System (BLIS).
ERIC Educational Resources Information Center
Library Software Review, 1984
1984-01-01
Describes online catalog and integrated library computer system designed to enhance Washington Library Network's software. Highlights include system components; implementation options; system features (integrated library functions, database design, system management facilities); support services (installation and training, software maintenance and…
A novel image database analysis system for maintenance of transportation facility : phase I.
DOT National Transportation Integrated Search
2010-06-01
Transportation is critical to the global economy and plays a particularly vital role in this regions economic growth. Transportation infrastructures such as highways, streets, and bridges represent one of the largest public investments of many gov...
Comprehensive Data Collected from the Petroleum Refining Sector
On April 1, 2011 EPA sent a comprehensive industry-wide information collection request (ICR) to all facilities in the U.S. petroleum refining industry. EPA has received this ICR data and compiled these data into databases and spreadsheets for the web
Correlates of quality educational programs.
Chester, Deborah R; Tracy, Jessamyn A; Earp, Emily; Chauhan, Reetu
2002-06-01
Preliminary evaluation findings are presented that explore relationships between educational program quality and program characteristics such as program type, security level, aftercare, teacher certification, facility size, and private versus public provider. Several program characteristics are found to be related to measurements of educational program quality. Among the major quality characteristics are proportion of program teachers that are professionally certified, smaller sized facilities versus larger facilities, level of aftercare services, and provider sources, with private for-profit providers being the lowest performing and public providers being the highest performing. The article closes with description of the Juvenile Justice Educational Enhancement Program's continuing evaluation of correlates to educational program quality through the continued development of a comprehensive database.
Kuhn, Stefan; Schlörer, Nils E
2015-08-01
nmrshiftdb2 supports with its laboratory information management system the integration of an electronic lab administration and management into academic NMR facilities. Also, it offers the setup of a local database, while full access to nmrshiftdb2's World Wide Web database is granted. This freely available system allows on the one hand the submission of orders for measurement, transfers recorded data automatically or manually, and enables download of spectra via web interface, as well as the integrated access to prediction, search, and assignment tools of the NMR database for lab users. On the other hand, for the staff and lab administration, flow of all orders can be supervised; administrative tools also include user and hardware management, a statistic functionality for accounting purposes, and a 'QuickCheck' function for assignment control, to facilitate quality control of assignments submitted to the (local) database. Laboratory information management system and database are based on a web interface as front end and are therefore independent of the operating system in use. Copyright © 2015 John Wiley & Sons, Ltd.
NASA Technical Reports Server (NTRS)
Pamadi, Bandu N.; Pei, Jing; Covell, Peter F.; Favaregh, Noah M.; Gumbert, Clyde R.; Hanke, Jeremy L.
2011-01-01
NASA Langley Research Center, in partnership with NASA Marshall Space Flight Center and NASA Ames Research Center, was involved in the aerodynamic analyses, testing, and database development for the Ares I A106 crew launch vehicle in support of the Ares Design and Analysis Cycle. This paper discusses the development of lift-off/transition and ascent databases. The lift-off/transition database was developed using data from tests on a 1.75% scale model of the A106 configuration in the NASA Langley 14x22 Subsonic Wind Tunnel. The power-off ascent database was developed using test data on a 1% A106 scale model from two different facilities, the Boeing Polysonic Wind Tunnel and the NASA Langley Unitary Plan Wind Tunnel. The ascent database was adjusted for differences in wind tunnel and flight Reynolds numbers using USM3D CFD code. The aerodynamic jet interaction effects due to first stage roll control system were modeled using USM3D and OVERFLOW CFD codes.
Nuclear data activities at the n_TOF facility at CERN
NASA Astrophysics Data System (ADS)
Gunsing, F.; Aberle, O.; Andrzejewski, J.; Audouin, L.; Bécares, V.; Bacak, M.; Balibrea-Correa, J.; Barbagallo, M.; Barros, S.; Bečvář, F.; Beinrucker, C.; Belloni, F.; Berthoumieux, E.; Billowes, J.; Bosnar, D.; Brugger, M.; Caamaño, M.; Calviño, F.; Calviani, M.; Cano-Ott, D.; Cardella, R.; Casanovas, A.; Castelluccio, D. M.; Cerutti, F.; Chen, Y. H.; Chiaveri, E.; Colonna, N.; Cortés-Giraldo, M. A.; Cortés, G.; Cosentino, L.; Damone, L. A.; Deo, K.; Diakaki, M.; Domingo-Pardo, C.; Dressler, R.; Dupont, E.; Durán, I.; Fernández-Domínguez, B.; Ferrari, A.; Ferreira, P.; Finocchiaro, P.; Frost, R. J. W.; Furman, V.; Ganesan, S.; García, A. R.; Gawlik, A.; Gheorghe, I.; Glodariu, T.; Gonçalves, I. F.; González, E.; Goverdovski, A.; Griesmayer, E.; Guerrero, C.; Göbel, K.; Harada, H.; Heftrich, T.; Heinitz, S.; Hernández-Prieto, A.; Heyse, J.; Jenkins, D. G.; Jericha, E.; Käppeler, F.; Kadi, Y.; Katabuchi, T.; Kavrigin, P.; Ketlerov, V.; Khryachkov, V.; Kimura, A.; Kivel, N.; Kokkoris, M.; Krtička, M.; Leal-Cidoncha, E.; Lederer, C.; Leeb, H.; Lerendegui, J.; Licata, M.; Lo Meo, S.; Lonsdale, S. J.; Losito, R.; Macina, D.; Marganiec, J.; Martínez, T.; Masi, A.; Massimi, C.; Mastinu, P.; Mastromarco, M.; Matteucci, F.; Maugeri, E. A.; Mazzone, A.; Mendoza, E.; Mengoni, A.; Milazzo, P. M.; Mingrone, F.; Mirea, M.; Montesano, S.; Musumarra, A.; Nolte, R.; Oprea, A.; Palomo-Pinto, F. R.; Paradela, C.; Patronis, N.; Pavlik, A.; Perkowski, J.; Porras, I.; Praena, J.; Quesada, J. M.; Rajeev, K.; Rauscher, T.; Reifarth, R.; Riego-Perez, A.; Robles, M.; Rout, P.; Radeck, D.; Rubbia, C.; Ryan, J. A.; Sabaté-Gilarte, M.; Saxena, A.; Schillebeeckx, P.; Schmidt, S.; Schumann, D.; Sedyshev, P.; Smith, A. G.; Stamatopoulos, A.; Suryanarayana, S. V.; Tagliente, G.; Tain, J. L.; Tarifeño-Saldivia, A.; Tarrío, D.; Tassan-Got, L.; Tsinganis, A.; Valenta, S.; Vannini, G.; Variale, V.; Vaz, P.; Ventura, A.; Vlachoudis, V.; Vlastou, R.; Wallner, A.; Warren, S.; Weigand, M.; Weiss, C.; Wolf, C.; Woods, P. J.; Wright, T.; Žugec, P.
2016-10-01
Nuclear data in general, and neutron-induced reaction cross sections in particular, are important for a wide variety of research fields. They play a key role in the safety and criticality assessment of nuclear technology, not only for existing power reactors but also for radiation dosimetry, medical applications, the transmutation of nuclear waste, accelerator-driven systems, fuel cycle investigations and future reactor systems as in Generation IV. Applications of nuclear data are also related to research fields as the study of nuclear level densities and stellar nucleosynthesis. Simulations and calculations of nuclear technology applications largely rely on evaluated nuclear data libraries. The evaluations in these libraries are based both on experimental data and theoretical models. Experimental nuclear reaction data are compiled on a worldwide basis by the international network of Nuclear Reaction Data Centres (NRDC) in the EXFOR database. The EXFOR database forms an important link between nuclear data measurements and the evaluated data libraries. CERN's neutron time-of-flight facility n_TOF has produced a considerable amount of experimental data since it has become fully operational with the start of the scientific measurement programme in 2001. While for a long period a single measurement station (EAR1) located at 185 m from the neutron production target was available, the construction of a second beam line at 20 m (EAR2) in 2014 has substantially increased the measurement capabilities of the facility. An outline of the experimental nuclear data activities at CERN's neutron time-of-flight facility n_TOF will be presented.
A Bioinformatics Facility for NASA
NASA Technical Reports Server (NTRS)
Schweighofer, Karl; Pohorille, Andrew
2006-01-01
Building on an existing prototype, we have fielded a facility with bioinformatics technologies that will help NASA meet its unique requirements for biological research. This facility consists of a cluster of computers capable of performing computationally intensive tasks, software tools, databases and knowledge management systems. Novel computational technologies for analyzing and integrating new biological data and already existing knowledge have been developed. With continued development and support, the facility will fulfill strategic NASA s bioinformatics needs in astrobiology and space exploration. . As a demonstration of these capabilities, we will present a detailed analysis of how spaceflight factors impact gene expression in the liver and kidney for mice flown aboard shuttle flight STS-108. We have found that many genes involved in signal transduction, cell cycle, and development respond to changes in microgravity, but that most metabolic pathways appear unchanged.
DOT National Transportation Integrated Search
2006-05-01
This research has provided NCDOT with (1) scientific observations to validate the pollutant removal : performance of selected structural BMPs, (2) a database management option for BMP monitoring and : non-monitoring sites, (3) pollution prevention pl...
Report #16-P-0164, May 3, 2016. Accurate enforcement databases and updated CMS plans promote effective and efficient EPA oversight of compliance programs, and help to protect the public from harmful air pollutants.
Writing Apprehension, Computer Anxiety and Telecomputing: A Pilot Study.
ERIC Educational Resources Information Center
Harris, Judith; Grandgenett, Neal
1992-01-01
A study measured graduate students' writing apprehension and computer anxiety levels before and after using electronic mail, computer conferencing, and remote database searching facilities during an educational technology course. Results indicted postcourse computer anxiety levels significantly related to usage statistics. Precourse writing…
42 CFR 436.407 - Types of acceptable documentary evidence of citizenship.
Code of Federal Regulations, 2012 CFR
2012-10-01
... (including general education and high school equivalency diplomas), marriage certificates, divorce decrees... perjury by a residential care facility director or administrator on behalf of an institutionalized... State database subsequent changes in eligibility should not require repeating the documentation of...
42 CFR 436.407 - Types of acceptable documentary evidence of citizenship.
Code of Federal Regulations, 2013 CFR
2013-10-01
... (including general education and high school equivalency diplomas), marriage certificates, divorce decrees... perjury by a residential care facility director or administrator on behalf of an institutionalized... State database subsequent changes in eligibility should not require repeating the documentation of...
78 FR 23690 - Airworthiness Directives; The Boeing Company
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-22
... management system (CMS) configuration database; and installing new operational program software (OPS) for the CSCP, zone management unit (ZMU), passenger address controller, cabin interphone controller, cabin area... on the Internet at http://www.regulations.gov ; or in person at the Docket Management Facility...
Code of Federal Regulations, 2014 CFR
2014-04-01
... trading; and (iv) Identification of each account to which fills are allocated. (3) Electronic analysis capability. A swap execution facility's audit trail program shall include electronic analysis capability with respect to all audit trail data in the transaction history database. Such electronic analysis capability...
Request for Determination on BACT Issues -- Ogden Martin Tulsa Municipal Waste Incinerator Facility
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Determination of Whether Emissions From Seagram and Sons Whiskey Storage Facility are Fugitive
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Source Definition Issue for KN Power - Front Range Energy Associates, LLC/PSCo Generating Facility
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
NASA Technical Reports Server (NTRS)
Shapiro, Linda G.; Tanimoto, Steven L.; Ahrens, James P.
1996-01-01
The goal of this task was to create a design and prototype implementation of a database environment that is particular suited for handling the image, vision and scientific data associated with the NASA's EOC Amazon project. The focus was on a data model and query facilities that are designed to execute efficiently on parallel computers. A key feature of the environment is an interface which allows a scientist to specify high-level directives about how query execution should occur.
Ships Docked at Title V Permitted Facilities
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Policy and Guidance Database available at www2.epa.gov/title-v-operating-permits/title-v-operating-permit-policy-and-guidance-document-index. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
PSD Applicability for a PSD-Avoidance Permit Action for Intermet Corporation's Archer Creek Facility
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
PSD Applicability Determination for Multiple Owner/Operator Point Sources Within a Single Facility
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
A database system to support image algorithm evaluation
NASA Technical Reports Server (NTRS)
Lien, Y. E.
1977-01-01
The design is given of an interactive image database system IMDB, which allows the user to create, retrieve, store, display, and manipulate images through the facility of a high-level, interactive image query (IQ) language. The query language IQ permits the user to define false color functions, pixel value transformations, overlay functions, zoom functions, and windows. The user manipulates the images through generic functions. The user can direct images to display devices for visual and qualitative analysis. Image histograms and pixel value distributions can also be computed to obtain a quantitative analysis of images.
De-MA: a web Database for electron Microprobe Analyses to assist EMP lab manager and users
NASA Astrophysics Data System (ADS)
Allaz, J. M.
2012-12-01
Lab managers and users of electron microprobe (EMP) facilities require comprehensive, yet flexible documentation structures, as well as an efficient scheduling mechanism. A single on-line database system for managing reservations, and providing information on standards, quantitative and qualitative setups (element mapping, etc.), and X-ray data has been developed for this purpose. This system is particularly useful in multi-user facilities where experience ranges from beginners to the highly experienced. New users and occasional facility users will find these tools extremely useful in developing and maintaining high quality, reproducible, and efficient analyses. This user-friendly database is available through the web, and uses MySQL as a database and PHP/HTML as script language (dynamic website). The database includes several tables for standards information, X-ray lines, X-ray element mapping, PHA, element setups, and agenda. It is configurable for up to five different EMPs in a single lab, each of them having up to five spectrometers and as many diffraction crystals as required. The installation should be done on a web server supporting PHP/MySQL, although installation on a personal computer is possible using third-party freeware to create a local Apache server, and to enable PHP/MySQL. Since it is web-based, any user outside the EMP lab can access this database anytime through any web browser and on any operating system. The access can be secured using a general password protection (e.g. htaccess). The web interface consists of 6 main menus. (1) "Standards" lists standards defined in the database, and displays detailed information on each (e.g. material type, name, reference, comments, and analyses). Images such as EDS spectra or BSE can be associated with a standard. (2) "Analyses" lists typical setups to use for quantitative analyses, allows calculation of mineral composition based on a mineral formula, or calculation of mineral formula based on a fixed amount of oxygen, or of cation (using an analysis in element or oxide weight-%); this latter includes re-calculation of H2O/CO2 based on stoichiometry, and oxygen correction for F and Cl. Another option offers a list of any available standards and possible peak or background interferences for a series of elements. (3) "X-ray maps" lists the different setups recommended for element mapping using WDS, and a map calculator to facilitate maps setups and to estimate the total mapping time. (4) "X-ray data" lists all x-ray lines for a specific element (K, L, M, absorption edges, and satellite peaks) in term of energy, wavelength and peak position. A check for possible interferences on peak or background is also possible. Theoretical x-ray peak positions for each crystal are calculated based on the 2d spacing of each crystal and the wavelength of each line. (5) "Agenda" menu displays the reservation dates for each month and for each EMP lab defined. It also offers a reservation request option, this request being sent by email to the EMP manager for approval. (6) Finally, "Admin" is password restricted, and contains all necessary options to manage the database through user-friendly forms. The installation of this database is made easy and knowledge of HTML, PHP, or MySQL is unnecessary to install, configure, manage, or use it. A working database is accessible at http://cub.geoloweb.ch.
Eglin virtual range database for hardware-in-the-loop testing
NASA Astrophysics Data System (ADS)
Talele, Sunjay E.; Pickard, J. W., Jr.; Owens, Monte A.; Foster, Joseph; Watson, John S.; Amick, Mary Amenda; Anthony, Kenneth
1998-07-01
Realistic backgrounds are necessary to support high fidelity hardware-in-the-loop testing. Advanced avionics and weapon system sensors are driving the requirement for higher resolution imagery. The model-test-model philosophy being promoted by the T&E community is resulting in the need for backgrounds that are realistic or virtual representations of actual test areas. Combined, these requirements led to a major upgrade of the terrain database used for hardware-in-the-loop testing at the Guided Weapons Evaluation Facility (GWEF) at Eglin Air Force Base, Florida. This paper will describe the process used to generate the high-resolution (1-foot) database of ten sites totaling over 20 square kilometers of the Eglin range. this process involved generating digital elevation maps from stereo aerial imagery and classifying ground cover material using the spectral content. These databases were then optimized for real-time operation at 90 Hz.
NCBI GEO: mining tens of millions of expression profiles--database and tools update.
Barrett, Tanya; Troup, Dennis B; Wilhite, Stephen E; Ledoux, Pierre; Rudnev, Dmitry; Evangelista, Carlos; Kim, Irene F; Soboleva, Alexandra; Tomashevsky, Maxim; Edgar, Ron
2007-01-01
The Gene Expression Omnibus (GEO) repository at the National Center for Biotechnology Information (NCBI) archives and freely disseminates microarray and other forms of high-throughput data generated by the scientific community. The database has a minimum information about a microarray experiment (MIAME)-compliant infrastructure that captures fully annotated raw and processed data. Several data deposit options and formats are supported, including web forms, spreadsheets, XML and Simple Omnibus Format in Text (SOFT). In addition to data storage, a collection of user-friendly web-based interfaces and applications are available to help users effectively explore, visualize and download the thousands of experiments and tens of millions of gene expression patterns stored in GEO. This paper provides a summary of the GEO database structure and user facilities, and describes recent enhancements to database design, performance, submission format options, data query and retrieval utilities. GEO is accessible at http://www.ncbi.nlm.nih.gov/geo/
CADB: Conformation Angles DataBase of proteins
Sheik, S. S.; Ananthalakshmi, P.; Bhargavi, G. Ramya; Sekar, K.
2003-01-01
Conformation Angles DataBase (CADB) provides an online resource to access data on conformation angles (both main-chain and side-chain) of protein structures in two data sets corresponding to 25% and 90% sequence identity between any two proteins, available in the Protein Data Bank. In addition, the database contains the necessary crystallographic parameters. The package has several flexible options and display facilities to visualize the main-chain and side-chain conformation angles for a particular amino acid residue. The package can also be used to study the interrelationship between the main-chain and side-chain conformation angles. A web based JAVA graphics interface has been deployed to display the user interested information on the client machine. The database is being updated at regular intervals and can be accessed over the World Wide Web interface at the following URL: http://144.16.71.148/cadb/. PMID:12520049
ESO telbib: Linking In and Reaching Out
NASA Astrophysics Data System (ADS)
Grothkopf, U.; Meakins, S.
2015-04-01
Measuring an observatory's research output is an integral part of its science operations. Like many other observatories, ESO tracks scholarly papers that use observational data from ESO facilities and uses state-of-the-art tools to create, maintain, and further develop the Telescope Bibliography database (telbib). While telbib started out as a stand-alone tool mostly used to compile lists of papers, it has by now developed into a multi-faceted, interlinked system. The core of the telbib database is links between scientific papers and observational data generated by the La Silla Paranal Observatory residing in the ESO archive. This functionality has also been deployed for ALMA data. In addition, telbib reaches out to several other systems, including ESO press releases, the NASA ADS Abstract Service, databases at the CDS Strasbourg, and impact scores at Altmetric.com. We illustrate these features to show how the interconnected telbib system enhances the content of the database as well as the user experience.
Drozdovitch, Vladimir; Zhukova, Olga; Germenchuk, Maria; Khrutchinsky, Arkady; Kukhta, Tatiana; Luckyanov, Nickolas; Minenko, Victor; Podgaiskaya, Marina; Savkin, Mikhail; Vakulovsky, Sergey; Voillequé, Paul; Bouville, André
2012-01-01
Results of all available meteorological and radiation measurements that were performed in Belarus during the first three months after the Chernobyl accident were collected from various sources and incorporated into a single database. Meteorological information such as precipitation, wind speed and direction, and temperature in localities were obtained from meteorological station facilities. Radiation measurements include gamma-exposure rate in air, daily fallout, concentration of different radionuclides in soil, grass, cow’s milk and water as well as total beta-activity in cow’s milk. Considerable efforts were made to evaluate the reliability of the measurements that were collected. The electronic database can be searched according to type of measurement, date, and location. The main purpose of the database is to provide reliable data that can be used in the reconstruction of thyroid doses resulting from the Chernobyl accident. PMID:23103580
NASA Technical Reports Server (NTRS)
Reardon, John E.; Violett, Duane L., Jr.
1991-01-01
The AFAS Database System was developed to provide the basic structure of a comprehensive database system for the Marshall Space Flight Center (MSFC) Structures and Dynamics Laboratory Aerophysics Division. The system is intended to handle all of the Aerophysics Division Test Facilities as well as data from other sources. The system was written for the DEC VAX family of computers in FORTRAN-77 and utilizes the VMS indexed file system and screen management routines. Various aspects of the system are covered, including a description of the user interface, lists of all code structure elements, descriptions of the file structures, a description of the security system operation, a detailed description of the data retrieval tasks, a description of the session log, and a description of the archival system.
Update on Geothermal Direct-Use Installations in the United States
Beckers, Koenraad F.; Snyder, Diana M.; Young, Katherine R.
2017-03-02
An updated database of geothermal direct-use systems in the U.S. has been compiled and analyzed, building upon the Oregon Institute of Technology (OIT) Geo-Heat Center direct-use database. Types of direct-use applications examined include hot springs resorts and pools, aquaculture farms, greenhouses, and district heating systems, among others; power-generating facilities and ground-source heat pumps were excluded. Where possible, the current operation status, open and close dates, well data, and other technical data were obtained for each entry. The database contains 545 installations, of which 407 are open, 108 are closed, and 30 have an unknown status. A report is also included which details and analyzes current geothermal direct-use installations and barriers to further implementation.
Restructuring in response to case mix reimbursement in nursing homes: A contingency approach
Zinn, Jacqueline; Feng, Zhanlian; Mor, Vincent; Intrator, Orna; Grabowski, David
2013-01-01
Background Resident-based case mix reimbursement has become the dominant mechanism for publicly funded nursing home care. In 1998 skilled nursing facility reimbursement changed from cost-based to case mix adjusted payments under the Medicare Prospective Payment System for the costs of all skilled nursing facility care provided to Medicare recipients. In addition, as of 2004, 35 state Medicaid programs had implemented some form of case mix reimbursement. Purpose The purpose of the study is to determine if the implementation of Medicare and Medicaid case mix reimbursement increased the administrative burden on nursing homes, as evidenced by increased levels of nurses in administrative functions. Methodology/Approach The primary data for this study come from the Centers for Medicare and Medicaid Services Online Survey Certification and Reporting database from 1997 through 2004, a national nursing home database containing aggregated facility-level information, including staffing, organizational characteristics and resident conditions, on all Medicare/Medicaid certified nursing facilities in the country. We conducted multivariate regression analyses using a facility fixed-effects model to examine the effects of the implementation of Medicaid case mix reimbursement and Medicare Prospective Payment System on changes in the level of total administrative nurse staffing in nursing homes. Findings Both Medicaid case mix reimbursement and Medicare Prospective Payment System increased the level of administrative nurse staffing, on average by 5.5% and 4.0% respectively. However, lack of evidence for a substitution effect suggests that any decline in direct care staffing after the introduction of case mix reimbursement is not attributable to a shift from clinical nursing resources to administrative functions. Practice Implications Our findings indicate that the administrative burden posed by case mix reimbursement has resource implications for all freestanding facilities. At the margin, the increased administrative burden imposed by case mix may become a factor influencing a range of decisions, including resident admission and staff hiring. PMID:18360162
Restructuring in response to case mix reimbursement in nursing homes: a contingency approach.
Zinn, Jacqueline; Feng, Zhanlian; Mor, Vincent; Intrator, Orna; Grabowski, David
2008-01-01
Resident-based case mix reimbursement has become the dominant mechanism for publicly funded nursing home care. In 1998 skilled nursing facility reimbursement changed from cost-based to case mix adjusted payments under the Medicare Prospective Payment System for the costs of all skilled nursing facility care provided to Medicare recipients. In addition, as of 2004, 35 state Medicaid programs had implemented some form of case mix reimbursement. The purpose of the study is to determine if the implementation of Medicare and Medicaid case mix reimbursement increased the administrative burden on nursing homes, as evidenced by increased levels of nurses in administrative functions. The primary data for this study come from the Centers for Medicare and Medicaid Services Online Survey Certification and Reporting database from 1997 through 2004, a national nursing home database containing aggregated facility-level information, including staffing, organizational characteristics and resident conditions, on all Medicare/Medicaid certified nursing facilities in the country. We conducted multivariate regression analyses using a facility fixed-effects model to examine the effects of the implementation of Medicaid case mix reimbursement and Medicare Prospective Payment System on changes in the level of total administrative nurse staffing in nursing homes. Both Medicaid case mix reimbursement and Medicare Prospective Payment System increased the level of administrative nurse staffing, on average by 5.5% and 4.0% respectively. However, lack of evidence for a substitution effect suggests that any decline in direct care staffing after the introduction of case mix reimbursement is not attributable to a shift from clinical nursing resources to administrative functions. Our findings indicate that the administrative burden posed by case mix reimbursement has resource implications for all freestanding facilities. At the margin, the increased administrative burden imposed by case mix may become a factor influencing a range of decisions, including resident admission and staff hiring.
Shreay, Sanatan; Ma, Martin; McCluskey, Jill; Mittelhammer, Ron C; Gitlin, Matthew; Stephens, J Mark
2014-01-01
Objective To explore the relative efficiency of dialysis facilities in the United States and identify factors that are associated with efficiency in the production of dialysis treatments. Data Sources/Study Setting Medicare cost report data from 4,343 free-standing dialysis facilities in the United States that offered in-center hemodialysis in 2010. Study Design A cross-sectional, facility-level retrospective database analysis, utilizing data envelopment analysis (DEA) to estimate facility efficiency. Data Collection/Extraction Methods Treatment data and cost and labor inputs of dialysis treatments were obtained from 2010 Medicare Renal Cost Reports. Demographic data were obtained from the 2010 U.S. Census. Principal Findings Only 26.6 percent of facilities were technically efficient. Neither the intensity of market competition nor the profit status of the facility had a significant effect on efficiency. Facilities that were members of large chains were less likely to be efficient. Cost and labor savings due to changes in drug protocols had little effect on overall dialysis center efficiency. Conclusions The majority of free-standing dialysis facilities in the United States were functioning in a technically inefficient manner. As payment systems increasingly employ capitation and bundling provisions, these institutions will need to evaluate their efficiency to remain competitive. PMID:24237043
Enabling Cross-Discipline Collaboration Via a Functional Data Model
NASA Astrophysics Data System (ADS)
Lindholm, D. M.; Wilson, A.; Baltzer, T.
2016-12-01
Many research disciplines have very specialized data models that are used to express the detailed semantics that are meaningful to that community and easily utilized by their data analysis tools. While invaluable to members of that community, such expressive data structures and metadata are of little value to potential collaborators from other scientific disciplines. Many data interoperability efforts focus on the difficult task of computationally mapping concepts from one domain to another to facilitate discovery and use of data. Although these efforts are important and promising, we have found that a great deal of discovery and dataset understanding still happens at the level of less formal, personal communication. However, a significant barrier to inter-disciplinary data sharing that remains is one of data access.Scientists and data analysts continue to spend inordinate amounts of time simply trying to get data into their analysis tools. Providing data in a standard file format is often not sufficient since data can be structured in many ways. Adhering to more explicit community standards for data structure and metadata does little to help those in other communities.The Functional Data Model specializes the Relational Data Model (used by many database systems)by defining relations as functions between independent (domain) and dependent (codomain) variables. Given that arrays of data in many scientific data formats generally represent functionally related parameters (e.g. temperature as a function of space and time), the Functional Data Model is quite relevant for these datasets as well. The LaTiS software framework implements the Functional Data Model and provides a mechanism to expose an existing data source as a LaTiS dataset. LaTiS datasets can be manipulated using a Functional Algebra and output in any number of formats.LASP has successfully used the Functional Data Model and its implementation in the LaTiS software framework to bridge the gap between disparate data sources and communities. This presentation will demonstrate the utility of the Functional Data Model and how it can be used to facilitate cross-discipline collaboration.
47 CFR 69.307 - General support facilities.
Code of Federal Regulations, 2014 CFR
2014-10-01
....307 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED... computer investment used in the provision of the Line Information Database sub-element at § 69.120(b) shall be assigned to that sub-element. (b) General purpose computer investment used in the provision of the...
47 CFR 69.307 - General support facilities.
Code of Federal Regulations, 2010 CFR
2010-10-01
....307 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED... computer investment used in the provision of the Line Information Database sub-element at § 69.120(b) shall be assigned to that sub-element. (b) General purpose computer investment used in the provision of the...
47 CFR 69.307 - General support facilities.
Code of Federal Regulations, 2011 CFR
2011-10-01
....307 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED... computer investment used in the provision of the Line Information Database sub-element at § 69.120(b) shall be assigned to that sub-element. (b) General purpose computer investment used in the provision of the...
47 CFR 69.307 - General support facilities.
Code of Federal Regulations, 2012 CFR
2012-10-01
....307 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED... computer investment used in the provision of the Line Information Database sub-element at § 69.120(b) shall be assigned to that sub-element. (b) General purpose computer investment used in the provision of the...
47 CFR 69.307 - General support facilities.
Code of Federal Regulations, 2013 CFR
2013-10-01
....307 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED... computer investment used in the provision of the Line Information Database sub-element at § 69.120(b) shall be assigned to that sub-element. (b) General purpose computer investment used in the provision of the...
42 CFR 435.407 - Types of acceptable documentary evidence of citizenship.
Code of Federal Regulations, 2012 CFR
2012-10-01
... accredited institutions (including general education and high school equivalency diplomas), marriage... under penalty of perjury by a residential care facility director or administrator on behalf of an... documented and recorded in a State database subsequent changes in eligibility should not require repeating...
42 CFR 435.407 - Types of acceptable documentary evidence of citizenship.
Code of Federal Regulations, 2013 CFR
2013-10-01
... accredited institutions (including general education and high school equivalency diplomas), marriage... under penalty of perjury by a residential care facility director or administrator on behalf of an... documented and recorded in a State database subsequent changes in eligibility should not require repeating...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Warrant, Marilyn M.; Garcia, Rudy J.; Zhang, Pengchu
2004-09-15
Tomcat-Projects_RF is a software package for analyzing sensor data obtained from a database and displaying the results with Java Servlet Pages (JSP). SQL Views into the dataset are tailored for personnel having different roles in monitoring the items in a storage facility. For example, an inspector, a host treaty compliance officer, a system engineer and software developers were the users identified that would need to access data at different levels of detail, The analysis provides a high level status of the storage facility and allows the user to go deeper into the data details if the user desires.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Husler, R.O.; Weir, T.J.
1991-01-01
An enhanced maintenance program is being established to characterize and monitor cables, components, and process response at the Savannah River Site, Defense Waste Processing Facility. This facility was designed and constructed to immobilize the radioactive waste currently stored in underground storage tanks and is expected to begin operation in 1993. The plant is initiating the program to baseline and monitor instrument and control (I C) and electrical equipment, remote process equipment, embedded instrument and control cables, and in-cell jumper cables used in the facility. This program is based on the electronic characterization and diagnostic (ECAD) system which was modified tomore » include process response analysis and to meet rigid Department of Energy equipment requirements. The system consists of computer-automated, state-of-the-art electronics. The data that are gathered are stored in a computerized database for analysis, trending, and troubleshooting. It is anticipated that the data which are gathered and trended will aid in life extension for the facility.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Husler, R.O.; Weir, T.J.
1991-12-31
An enhanced maintenance program is being established to characterize and monitor cables, components, and process response at the Savannah River Site, Defense Waste Processing Facility. This facility was designed and constructed to immobilize the radioactive waste currently stored in underground storage tanks and is expected to begin operation in 1993. The plant is initiating the program to baseline and monitor instrument and control (I&C) and electrical equipment, remote process equipment, embedded instrument and control cables, and in-cell jumper cables used in the facility. This program is based on the electronic characterization and diagnostic (ECAD) system which was modified to includemore » process response analysis and to meet rigid Department of Energy equipment requirements. The system consists of computer-automated, state-of-the-art electronics. The data that are gathered are stored in a computerized database for analysis, trending, and troubleshooting. It is anticipated that the data which are gathered and trended will aid in life extension for the facility.« less
SARS: Safeguards Accounting and Reporting Software
NASA Astrophysics Data System (ADS)
Mohammedi, B.; Saadi, S.; Ait-Mohamed, S.
In order to satisfy the requirements of the SSAC (State System for Accounting and Control of nuclear materials), for recording and reporting objectives; this computer program comes to bridge the gape between nuclear facilities operators and national inspection verifying records and delivering reports. The SARS maintains and generates at-facility safeguards accounting records and generates International Atomic Energy Agency (IAEA) safeguards reports based on accounting data input by the user at any nuclear facility. A database structure is built and BORLAND DELPHI programming language has been used. The software is designed to be user-friendly, to make extensive and flexible management of menus and graphs. SARS functions include basic physical inventory tacking, transaction histories and reporting. Access controls are made by different passwords.
Factors promoting resident deaths at aged care facilities in Japan: a review.
Sugimoto, Kentaro; Ogata, Yasuko; Kashiwagi, Masayo
2018-03-01
Due to an increasingly ageing population, the Japanese government has promoted elderly deaths in aged care facilities. However, existing facilities were not designed to provide resident end-of-life care and the proportion of aged care facility deaths is currently less than 10%. Consequently, the present review evaluated the factors that promote aged care facility resident deaths in Japan from individual- and facility-level perspectives to exploring factors associated with increased resident deaths. To achieve this, MEDLINE, CINAHL, Web of Science and Ichushi databases were searched on 23 January 2016. Influential factors were reviewed for two healthcare services (insourcing and outsourcing facilities) as well as external healthcare agencies operating outside facilities. Of the original 2324 studies retrieved, 42 were included in analysis. Of these studies, five focused on insourcing, two on outsourcing, seven on external agencies and observed facility/agency-level factors. The other 28 studies identified individual-level factors related to death in aged care facilities. The present review found that at both facility and individual levels, in-facility resident deaths were associated with healthcare service provision, confirmation of resident/family end-of-life care preference and staff education. Additionally, while outsourcing facilities did not require employment of physicians/nursing staff to accommodate resident death, these facilities required visits by physicians and nursing staff from external healthcare agencies as well as residents' healthcare input. This review also found few studies examining outsourcing facilities. The number of healthcare outsourcing facilities is rapidly increasing as a result of the Japanese government's new tax incentives. Consequently, there may be an increase in elderly deaths in outsourcing healthcare facilities. Accordingly, it is necessary to identify the factors associated with residents' deaths at outsourcing facilities. © 2016 The Authors. Health and Social Care in the Community Published by John Wiley & Sons Ltd.
Nuclear Science User Facilities (NSUF) Monthly Report March 2015
DOE Office of Scientific and Technical Information (OSTI.GOV)
Soelberg, Renae
Nuclear Science User Facilities (NSUF) Formerly: Advanced Test Reactor National Scientific User Facility (ATR NSUF) Monthly Report February 2015 Highlights; Jim Cole attended the OECD NEA Expert Group on Innovative Structural Materials meeting in Paris, France; Jim Lane and Doug Copsey of Writers Ink visited PNNL to prepare an article for the NSUF annual report; Brenden Heidrich briefed the Nuclear Energy Advisory Committee-Facilities Subcommittee on the Nuclear Energy Infrastructure Database project and provided them with custom reports for their upcoming visits to Argonne National Laboratory, Idaho National Laboratory, Oak Ridge National Laboratory and the Massachusetts Institute of Technology; and Universitymore » of California-Berkeley Principal Investigator Mehdi Balooch visited PNNL to observe measurements and help finalize plans for completing the desired suite of analyses. His visit was coordinated to coincide with the visit of Jim Lane and Doug Copsey.« less
10th European Zebrafish Meeting 2017, Budapest: Husbandry Workshop Summary.
Oltová, Jana; Barton, Carrie; Certal, Ana Catarina; Argenton, Francesco; Varga, Zoltán M
2018-01-02
A husbandry workshop on July 3, 2017, at the 10th European Zebrafish Meeting in Budapest, Hungary (July 3-July 7, 2017), focused on the standardization, optimization, and streamlining of fish facility procedures. Standardization can be achieved for example by developing novel software and hardware tools, such as a fish facility database for husbandry and environmental facility management (Zebrabase, Oltova), or a hand-held, air-pressurized fish feeder for consistent food distribution (Blowfish, Argenton). Streamlining is achieved when work hours are reduced, as with the standardized fish feeder, or by limiting the number and types of fish diets and observing the effect on animal welfare and performance (Barton). Testing the characteristics of new fish diets and observing whether they produce better experimental outcomes (Certal) optimizes diets and improves fish productivity. Collectively, the workshop presentations emphasized how consistency and harmonization of husbandry procedures within and across aquatic facilities yield reproducible scientific outcomes.
Web-Based Requesting and Scheduling Use of Facilities
NASA Technical Reports Server (NTRS)
Yeager, Carolyn M.
2010-01-01
Automated User's Training Operations Facility Utilization Request (AutoFUR) is prototype software that administers a Web-based system for requesting and allocating facilities and equipment for astronaut-training classes in conjunction with scheduling the classes. AutoFUR also has potential for similar use in such applications as scheduling flight-simulation equipment and instructors in commercial airplane-pilot training, managing preventive- maintenance facilities, and scheduling operating rooms, doctors, nurses, and medical equipment for surgery. Whereas requesting and allocation of facilities was previously a manual process that entailed examination of documents (including paper drawings) from different sources, AutoFUR partly automates the process and makes all of the relevant information available via the requester s computer. By use of AutoFUR, an instructor can fill out a facility-utilization request (FUR) form on line, consult the applicable flight manifest(s) to determine what equipment is needed and where it should be placed in the training facility, reserve the corresponding hardware listed in a training-hardware inventory database, search for alternative hardware if necessary, submit the FUR for processing, and cause paper forms to be printed. Auto-FUR also maintains a searchable archive of prior FURs.
Developing Modern Information Systems and Services: Africa's Challenges for the Future.
ERIC Educational Resources Information Center
Chowdhury, G. G.
1996-01-01
Discusses the current state of information systems and services in Africa, examines future possibilities, and suggests areas for improvement. Topics include the lack of automation; CD-ROM databases for accessibility to information sources; developing low-cost electronic communication facilities; Internet connectivity; dependence on imported…
Industry and electricity production facilities generate over 50 percent of greenhouse gas (GHG) emissions in the United States. There is a growing consensus among scientists that the primary cause of climate change is anthropogenic greenhouse gas (GHG) emissions. Reducing GHG emi...
Berkeley Lab - Materials Sciences Division
Postdoc Forum Research Highlights Awards Publications Database Events Calendar Newsletter Archive People ; Finance Templates Travel One-Stop Investigators Division Staff Facilities and Centers Staff Jobs People Division, please use the links here. An outline of the Division structure is available at the Organization
Informetrics: Exploring Databases as Analytical Tools.
ERIC Educational Resources Information Center
Wormell, Irene
1998-01-01
Advanced online search facilities and information retrieval techniques have increased the potential of bibliometric research. Discusses three case studies carried out by the Centre for Informetric Studies at the Royal School of Library Science (Denmark) on the internationality of international journals, informetric analyses on the World Wide Web,…
Zhai, Zhiqiang; Song, Guohua; Lu, Hongyu; He, Weinan; Yu, Lei
2017-09-01
Vehicle-specific power (VSP) has been found to be highly correlated with vehicle emissions. It is used in many studies on emission modeling such as the MOVES (Motor Vehicle Emissions Simulator) model. The existing studies develop specific VSP distributions (or OpMode distribution in MOVES) for different road types and various average speeds to represent the vehicle operating modes on road. However, it is still not clear if the facility- and speed-specific VSP distributions are consistent temporally and spatially. For instance, is it necessary to update periodically the database of the VSP distributions in the emission model? Are the VSP distributions developed in the city central business district (CBD) area applicable to its suburb area? In this context, this study examined the temporal and spatial consistency of the facility- and speed-specific VSP distributions in Beijing. The VSP distributions in different years and in different areas are developed, based on real-world vehicle activity data. The root mean square error (RMSE) is employed to quantify the difference between the VSP distributions. The maximum differences of the VSP distributions between different years and between different areas are approximately 20% of that between different road types. The analysis of the carbon dioxide (CO 2 ) emission factor indicates that the temporal and spatial differences of the VSP distributions have no significant impact on vehicle emission estimation, with relative error of less than 3%. The temporal and spatial differences have no significant impact on the development of the facility- and speed-specific VSP distributions for the vehicle emission estimation. The database of the specific VSP distributions in the VSP-based emission models can maintain in terms of time. Thus, it is unnecessary to update the database regularly, and it is reliable to use the history vehicle activity data to forecast the emissions in the future. In one city, the areas with less data can still develop accurate VSP distributions based on better data from other areas.
Rubin, Samuel J; Cohen, Michael B; Kirke, Diana N; Qureshi, Muhammad M; Truong, Minh Tam; Jalisi, Scharukh
2017-11-01
Determine whether facility type effects overall survival in patients with oral cavity cancer. Retrospective cohort study. Patients included in the National Cancer Database who were diagnosed with oral cavity cancer between 1998 and 2011 were included in the study. Data was stratified by facility where care was provided, including community cancer programs (CCP), comprehensive community cancer programs (CCCP), and academic centers (AC). Univariate analysis was performed using analysis of variance, chi squared, and log-rank test, whereas multivariate analysis was performed using Cox regression. A total of 32,510 patients were included in the study, with 7.58% of patients receiving care at CCPs (n = 2,553), 39.53% at CCCPs (n = 12,852), and 52.61% at ACs (n = 17,105). Between 1998 and 2011, there was a greater percentage of patients receiving care at ACs, and a greater percentage of patients receiving surgical therapy versus nonsurgical therapy. Patients treated at ACs had the best 5-year overall survival of 51.26%, with a significant difference across facility types (P < 0.01). After adjusting for confounders, receiving care at ACs was a positive predictor of survival (hazard ratio: 0.95 95% confidence interval [0.91,0.98])). Patients treated at ACs are more likely to receive surgical treatment, and have a greater 5-year overall survival compared to those patients treated at CCPs and CCCPs. Therefore, we advocate referring patients with advanced oral cavity cancers to ACs. 4. Laryngoscope, 127:2551-2557, 2017. © 2017 The American Laryngological, Rhinological and Otological Society, Inc.
Hugen, Cory M; Hu, Brian; Jeldres, Claudio; Burton, Claire; Nichols, Craig R; Porter, Christopher R; Daneshmand, Siamak
2016-11-01
Retroperitoneal lymph node dissection (RPLND) for the treatment of testicular cancer is a relatively rare and complex operation that may contribute to differences in utilization. We sought to characterize the use of RPLND between different categories of cancer center facilities in the United States. The National Cancer Database was queried for patients with germ cell tumors treated at different types of cancer centers between 1998 and 2011. The proportion of patients who underwent RPLND was stratified by stage and histology and then compared between treatment facilities. RPLND utilization was then compared between facility types as a function of time. A total of 59,652 patients met inclusion criteria and 5,475 (9.2%) underwent RPLND. The proportion of patients treated with RPLND for non-seminomatous germ cell tumor (NSGCT) was significantly different between cancer center types for all stages (P<0.001) and used most often in academic comprehensive cancer centers. There was no difference in the proportion of RPLND utilization for stage II and III seminoma stratified by treatment facility. There was a significantly decreased trend in the utilization of RPLND for stage I (P = 0.032) NSGCT whereas utilization was increased for stage III NSGCT (P≤0.001) over the study period. The proportion of patients undergoing RPLND for NSGCT varies significantly by the type of cancer center and is used most often in academic cancer centers. Utilization of RPLND decreased for stage I NSGCT and increased for stage III NSGCTs during the study period. Copyright © 2016 Elsevier Inc. All rights reserved.
REDIdb: the RNA editing database.
Picardi, Ernesto; Regina, Teresa Maria Rosaria; Brennicke, Axel; Quagliariello, Carla
2007-01-01
The RNA Editing Database (REDIdb) is an interactive, web-based database created and designed with the aim to allocate RNA editing events such as substitutions, insertions and deletions occurring in a wide range of organisms. The database contains both fully and partially sequenced DNA molecules for which editing information is available either by experimental inspection (in vitro) or by computational detection (in silico). Each record of REDIdb is organized in a specific flat-file containing a description of the main characteristics of the entry, a feature table with the editing events and related details and a sequence zone with both the genomic sequence and the corresponding edited transcript. REDIdb is a relational database in which the browsing and identification of editing sites has been simplified by means of two facilities to either graphically display genomic or cDNA sequences or to show the corresponding alignment. In both cases, all editing sites are highlighted in colour and their relative positions are detailed by mousing over. New editing positions can be directly submitted to REDIdb after a user-specific registration to obtain authorized secure access. This first version of REDIdb database stores 9964 editing events and can be freely queried at http://biologia.unical.it/py_script/search.html.
Nuclear data made easily accessible through the Notre Dame Nuclear Database
NASA Astrophysics Data System (ADS)
Khouw, Timothy; Lee, Kevin; Fasano, Patrick; Mumpower, Matthew; Aprahamian, Ani
2014-09-01
In 1994, the NNDC revolutionized nuclear research by providing a colorful, clickable, searchable database over the internet. Over the last twenty years, web technology has evolved dramatically. Our project, the Notre Dame Nuclear Database, aims to provide a more comprehensive and broadly searchable interactive body of data. The database can be searched by an array of filters which includes metadata such as the facility where a measurement is made, the author(s), or date of publication for the datum of interest. The user interface takes full advantage of HTML, a web markup language, CSS (cascading style sheets to define the aesthetics of the website), and JavaScript, a language that can process complex data. A command-line interface is supported that interacts with the database directly on a user's local machine which provides single command access to data. This is possible through the use of a standardized API (application programming interface) that relies upon well-defined filtering variables to produce customized search results. We offer an innovative chart of nuclides utilizing scalable vector graphics (SVG) to deliver users an unsurpassed level of interactivity supported on all computers and mobile devices. We will present a functional demo of our database at the conference.
GANESH: software for customized annotation of genome regions.
Huntley, Derek; Hummerich, Holger; Smedley, Damian; Kittivoravitkul, Sasivimol; McCarthy, Mark; Little, Peter; Sergot, Marek
2003-09-01
GANESH is a software package designed to support the genetic analysis of regions of human and other genomes. It provides a set of components that may be assembled to construct a self-updating database of DNA sequence, mapping data, and annotations of possible genome features. Once one or more remote sources of data for the target region have been identified, all sequences for that region are downloaded, assimilated, and subjected to a (configurable) set of standard database-searching and genome-analysis packages. The results are stored in compressed form in a relational database, and are updated automatically on a regular schedule so that they are always immediately available in their most up-to-date versions. A Java front-end, executed as a stand alone application or web applet, provides a graphical interface for navigating the database and for viewing the annotations. There are facilities for importing and exporting data in the format of the Distributed Annotation System (DAS), enabling a GANESH database to be used as a component of a DAS configuration. The system has been used to construct databases for about a dozen regions of human chromosomes and for three regions of mouse chromosomes.
Investigation of IGES for CAD/CAE data transfer
NASA Technical Reports Server (NTRS)
Zobrist, George W.
1989-01-01
In a CAD/CAE facility there is always the possibility that one may want to transfer the design graphics database from the native system to a non-native system. This may occur because of dissimilar systems within an organization or a new CAD/CAE system is to be purchased. The Initial Graphics Exchange Specification (IGES) was developed in an attempt to solve this scenario. IGES is a neutral database format into which the CAD/CAE native database format can be translated to and from. Translating the native design database format to IGES requires a pre-processor and transling from IGES to the native database format requires a post-processor. IGES is an artifice to represent CAD/CAE product data in a neutral environment to allow interfacing applications, archive the database, interchange of product data between dissimilar CAD/CAE systems, and other applications. The intent here is to present test data on translating design product data from a CAD/CAE system to itself and to translate data initially prepared in IGES format to various native design formats. This information can be utilized in planning potential procurement and developing a design discipline within the CAD/CAE community.
The DREO Elint Browser Utility (DEBU) reference manual
NASA Astrophysics Data System (ADS)
Ford, Barbara; Jones, David
1992-04-01
An electronic intelligent database browsing tool called DEBU has been developed that allows databases such as ELP, Kilting, EWIR, and AFEWC to be reviewed and analyzed from a user-friendly environment on a personal computer. DEBU's basic function is to allow users to examine the contents of user-selected subfiles of user-selected emitters of user-selected databases. DEBU augments this functionality with support for selecting (filtering) and combining subsets of emitters by user-selected attributes such as name, parameter type, or parameter value. DEBU provides facilities for examining histograms and x-y plots of selected parameters, for doing ambiguity analysis and mode level analysis, and for generating and printing a variety of reports. A manual is provided for users of DEBU, including descriptions and illustrations of menus and windows.
The Physiology Constant Database of Teen-Agers in Beijing
Wei-Qi, Wei; Guang-Jin, Zhu; Cheng-Li, Xu; Shao-Mei, Han; Bao-Shen, Qi; Li, Chen; Shu-Yu, Zu; Xiao-Mei, Zhou; Wen-Feng, Hu; Zheng-Guo, Zhang
2004-01-01
Physiology constants of adolescents are important to understand growing living systems and are a useful reference in clinical and epidemiological research. Until recently, physiology constants were not available in China and therefore most physiologists, physicians, and nutritionists had to use data from abroad for reference. However, the very difference between the Eastern and Western races casts doubt on the usefulness of overseas data. We have therefore created a database system to provide a repository for the storage of physiology constants of teen-agers in Beijing. The several thousands of pieces of data are now divided into hematological biochemistry, lung function, and cardiac function with all data manually checked before being transferred into the database. The database was accomplished through the development of a web interface, scripts, and a relational database. The physiology data were integrated into the relational database system to provide flexible facilities by using combinations of various terms and parameters. A web browser interface was designed for the users to facilitate their searching. The database is available on the web. The statistical table, scatter diagram, and histogram of the data are available for both anonym and user according to queries, while only the user can achieve detail, including download data and advanced search. PMID:15258669
A Database of Tornado Events as Perceived by the USArray Transportable Array Network
NASA Astrophysics Data System (ADS)
Tytell, J. E.; Vernon, F.; Reyes, J. C.
2015-12-01
Over the course of the deployment of Earthscope's USArray Transportable Array (TA) network there have numerous tornado events that have occurred within the changing footprint of its network. The Array Network Facility based in San Diego, California, has compiled a database of these tornado events based on data provided by the NOAA Storm Prediction Center (SPC). The SPC data itself consists of parameters such as start-end point track data for each event, maximum EF intensities, and maximum track widths. Our database is Antelope driven and combines these data from the SPC with detailed station information from the TA network. We are now able to list all available TA stations during any specific tornado event date and also provide a single calculated "nearest" TA station per individual tornado event. We aim to provide this database as a starting resource for those with an interest in investigating tornado signatures within surface pressure and seismic response data. On a larger scale, the database may be of particular interest to the infrasound research community
Design and implementation of a twin-family database for behavior genetics and genomics studies.
Boomsma, Dorret I; Willemsen, Gonneke; Vink, Jacqueline M; Bartels, Meike; Groot, Paul; Hottenga, Jouke Jan; van Beijsterveldt, C E M Toos; Stroet, Therese; van Dijk, Rob; Wertheim, Rien; Visser, Marco; van der Kleij, Frank
2008-06-01
In this article we describe the design and implementation of a database for extended twin families. The database does not focus on probands or on index twins, as this approach becomes problematic when larger multigenerational families are included, when more than one set of multiples is present within a family, or when families turn out to be part of a larger pedigree. Instead, we present an alternative approach that uses a highly flexible notion of persons and relations. The relations among the subjects in the database have a one-to-many structure, are user-definable and extendible and support arbitrarily complicated pedigrees. Some additional characteristics of the database are highlighted, such as the storage of historical data, predefined expressions for advanced queries, output facilities for individuals and relations among individuals and an easy-to-use multi-step wizard for contacting participants. This solution presents a flexible approach to accommodate pedigrees of arbitrary size, multiple biological and nonbiological relationships among participants and dynamic changes in these relations that occur over time, which can be implemented for any type of multigenerational family study.
Acquisitions. ERIC Processing Manual, Section II.
ERIC Educational Resources Information Center
Mathews, Gail, Ed.
Rules and guidelines are provided for the process of acquiring documents and journal articles to be considered for inclusion in the ERIC database. The differing responsibilities of the Government, the ERIC Clearinghouses, and the ERIC Facility are delineated. The various methods by which documentary material can be obtained are described. Sample…
WASTE ANALYSIS PLAN REVIEW ADVISOR - AN INTELLIGENT DATABASE TO ASSIST RCRA PERMIT REVIEWERS
The Waste Analysis Plan Review Advisor (WAPRA) system assists in the review of the Waste Analysis Plan Section of RCRA Part B facility permit applications. Specifically, this program automates two functions of the waste analysis plan review. First, the system checks all wastes wh...
The Arabization of a Full-Text Database Interface.
ERIC Educational Resources Information Center
Fayen, Emily Gallup; And Others
The 1981 design specifications for the Egyptian National Scientific and Technical Information Network (ENSTINET) stipulated that major end-user facilities of the system should be bilingual in English and Arabic. Many characteristics of the Arabic alphabet and language impact computer applications, and there exists no universally accepted character…
The report presents and evaluates the extensive database from the SITE Program demonstration at the MacGillis and Gibbs wood treatment facility in New Brighton, MN. Soil washing and segregation, biotreatment of contaminated process water, and biodegradation of a slurry of the con...
Interchange. November 1972-July 1983.
ERIC Educational Resources Information Center
Brandhorst, Ted, Ed.
The Interchange newsletter is prepared irregularly (approximately semiannually) by the staff of the ERIC Processing and Reference Facility in order to communicate matters of interest to users of the ERIC database and of other ERIC products and services. Initially, the focus was on computer-oriented users who were receiving the ERIC magnetic tapes…
LISA's Move from SilverPlatter to Bowker--Looking at the Interface.
ERIC Educational Resources Information Center
Stein, Jonathan
1994-01-01
Compares LISA (Library and Information Science Abstracts) on SilverPlatter's CD-ROM with its replacement version, Bowker-Saur's LISA Plus. Features reviewed include entry to the databases; use of Boolean search facilities; indexes and browsing; displaying and printing records; subsidiary functions; on-screen help; and interfaces. (Contains eight…
Natural Learning Case Study Archives
ERIC Educational Resources Information Center
Lawler, Robert W.
2015-01-01
Natural Learning Case Study Archives (NLCSA) is a research facility for those interested in using case study analysis to deepen their understanding of common sense knowledge and natural learning (how the mind interacts with everyday experiences to develop common sense knowledge). The database comprises three case study corpora based on experiences…
BP American Production Company's Florida River Compression Facility Single Source Determination
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Policy and Guidance Database available at www2.epa.gov/title-v-operating-permits/title-v-operating-permit-policy-and-guidance-document-index. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Calculating Potential to Emit (PTE) and Other Guidance for Grain Handling Facilities
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Policy and Guidance Database available at www2.epa.gov/title-v-operating-permits/title-v-operating-permit-policy-and-guidance-document-index. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Determination of Whether Emissions From Seagram and Sons Whiskey Storage Facility are Fugitive
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Policy and Guidance Database available at www2.epa.gov/title-v-operating-permits/title-v-operating-permit-policy-and-guidance-document-index. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
PSD Applicability Determination for Multiple Owner/Operator Point Sources Within a Single Facility
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Policy and Guidance Database available at www2.epa.gov/title-v-operating-permits/title-v-operating-permit-policy-and-guidance-document-index. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Technical Guidance for Title V Permitting of Printing Facilities
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Policy and Guidance Database available at www2.epa.gov/title-v-operating-permits/title-v-operating-permit-policy-and-guidance-document-index. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Is a Solvent Reclamation Facility Considered a Chemical Process Plant
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Policy and Guidance Database available at www2.epa.gov/title-v-operating-permits/title-v-operating-permit-policy-and-guidance-document-index. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Determinations for Four Different Situations Involving Contiguous and Adjacent Facilities
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Policy and Guidance Database available at www2.epa.gov/title-v-operating-permits/title-v-operating-permit-policy-and-guidance-document-index. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rohatgi, Upendra S.
Nuclear reactor codes require validation with appropriate data representing the plant for specific scenarios. The thermal-hydraulic data is scattered in different locations and in different formats. Some of the data is in danger of being lost. A relational database is being developed to organize the international thermal hydraulic test data for various reactor concepts and different scenarios. At the reactor system level, that data is organized to include separate effect tests and integral effect tests for specific scenarios and corresponding phenomena. The database relies on the phenomena identification sections of expert developed PIRTs. The database will provide a summary ofmore » appropriate data, review of facility information, test description, instrumentation, references for the experimental data and some examples of application of the data for validation. The current database platform includes scenarios for PWR, BWR, VVER, and specific benchmarks for CFD modelling data and is to be expanded to include references for molten salt reactors. There are place holders for high temperature gas cooled reactors, CANDU and liquid metal reactors. This relational database is called The International Experimental Thermal Hydraulic Systems (TIETHYS) database and currently resides at Nuclear Energy Agency (NEA) of the OECD and is freely open to public access. Going forward the database will be extended to include additional links and data as they become available. https://www.oecd-nea.org/tiethysweb/« less
Factors Affecting Discharge to Home of Geriatric Intermediate Care Facility Residents in Japan.
Morita, Kojiro; Ono, Sachiko; Ishimaru, Miho; Matsui, Hiroki; Naruse, Takashi; Yasunaga, Hideo
2018-04-01
To investigate factors associated with lower likelihood of discharge to home from geriatric intermediate care facilities in Japan. Retrospective cohort study. We used data from the nationwide long-term care (LTC) insurance claims database (April 2012-March 2014). Study participants were 342,758 individuals newly admitted to 3,459 geriatric intermediate care facilities during the study period. The primary outcome was discharge to home. We performed a multivariable competing-risk Cox regression with adjustment for resident-, facility-, and region-level characteristics. Resident level of care needs and several medical conditions were included as time-varying covariates. Death, admission to a hospital, and admission to another LTC facility were treated as competing risks. During the 2-year follow-up period, 19% of participants were discharged to home. In the multivariable competing-risk Cox regression, the following factors were significantly associated with lower likelihood of discharge to home: older age, higher level of care need, having several medical conditions, private ownership of the facility, more beds in the facility, and more LTC facility beds per 1,000 adults aged 65 and older in the region. Only 19% of residents were discharged to home. Our results are useful for policy-makers to promote discharge to home of older adults in geriatric intermediate care facilities. © 2018, Copyright the Authors Journal compilation © 2018, The American Geriatrics Society.
Observations of HF backscatter decay rates from HAARP generated FAI
NASA Astrophysics Data System (ADS)
Bristow, William; Hysell, David
2016-07-01
Suitable experiments at the High-frequency Active Auroral Research Program (HAARP) facilities in Gakona, Alaska, create a region of ionospheric Field-Aligned Irregularities (FAI) that produces strong radar backscatter observed by the SuperDARN radar on Kodiak Island, Alaska. Creation of FAI in HF ionospheric modification experiments has been studied by a number of authors who have developed a rich theoretical background. The decay of the irregularities, however, has not been so widely studied yet it has the potential for providing estimates of the parameters of natural irregularity diffusion, which are difficult measure by other means. Hysell, et al. [1996] demonstrated using the decay of radar scatter above the Sura heating facility to estimate irregularity diffusion. A large database of radar backscatter from HAARP generated FAI has been collected over the years. Experiments often cycled the heater power on and off in a way that allowed estimates of the FAI decay rate. The database has been examined to extract decay time estimates and diffusion rates over a range of ionospheric conditions. This presentation will summarize the database and the estimated diffusion rates, and will discuss the potential for targeted experiments for aeronomy measurements. Hysell, D. L., M. C. Kelley, Y. M. Yampolski, V. S. Beley, A. V. Koloskov, P. V. Ponomarenko, and O. F. Tyrnov, HF radar observations of decaying artificial field aligned irregularities, J. Geophys. Res. , 101, 26,981, 1996.
Observations of HF backscatter decay rates from HAARP generated FAI
NASA Astrophysics Data System (ADS)
Bristow, W. A.; Hysell, D. L.
2016-12-01
Suitable experiments at the High-frequency Active Auroral Research Program (HAARP) facilities in Gakona, Alaska, create a region of ionospheric Field-Aligned Irregularities (FAI) that produces strong radar backscatter observed by the SuperDARN radar on Kodiak Island, Alaska. Creation of FAI in HF ionospheric modification experiments has been studied by a number of authors who have developed a rich theoretical background. The decay of the irregularities, however, has not been so widely studied yet it has the potential for providing estimates of the parameters of natural irregularity diffusion, which are difficult measure by other means. Hysell, et al. [1996] demonstrated using the decay of radar scatter above the Sura heating facility to estimate irregularity diffusion. A large database of radar backscatter from HAARP generated FAI has been collected over the years. Experiments often cycled the heater power on and off in a way that allowed estimates of the FAI decay rate. The database has been examined to extract decay time estimates and diffusion rates over a range of ionospheric conditions. This presentation will summarize the database and the estimated diffusion rates, and will discuss the potential for targeted experiments for aeronomy measurements. Hysell, D. L., M. C. Kelley, Y. M. Yampolski, V. S. Beley, A. V. Koloskov, P. V. Ponomarenko, and O. F. Tyrnov, HF radar observations of decaying artificial field aligned irregularities, J. Geophys. Res. , 101, 26,981, 1996.
Performance Testing of a Trace Contaminant Control Subassembly for the International Space Station
NASA Technical Reports Server (NTRS)
Perry, J. L.; Curtis, R. E.; Alexandre, K. L.; Ruggiero, L. L.; Shtessel, N.
1998-01-01
As part of the International Space Station (ISS) Trace Contaminant Control Subassembly (TCCS) development, a performance test has been conducted to provide reference data for flight verification analyses. This test, which used the U.S. Habitation Module (U.S. Hab) TCCS as the test article, was designed to add to the existing database on TCCS performance. Included in this database are results obtained during ISS development testing; testing of functionally similar TCCS prototype units; and bench scale testing of activated charcoal, oxidation catalyst, and granular lithium hydroxide (LiOH). The present database has served as the basis for the development and validation of a computerized TCCS process simulation model. This model serves as the primary means for verifying the ISS TCCS performance. In order to mitigate risk associated with this verification approach, the U.S. Hab TCCS performance test provides an additional set of data which serve to anchor both the process model and previously-obtained development test data to flight hardware performance. The following discussion provides relevant background followed by a summary of the test hardware, objectives, requirements, and facilities. Facility and test article performance during the test is summarized, test results are presented, and the TCCS's performance relative to past test experience is discussed. Performance predictions made with the TCCS process model are compared with the U.S. Hab TCCS test results to demonstrate its validation.
MAGIC database and interfaces: an integrated package for gene discovery and expression.
Cordonnier-Pratt, Marie-Michèle; Liang, Chun; Wang, Haiming; Kolychev, Dmitri S; Sun, Feng; Freeman, Robert; Sullivan, Robert; Pratt, Lee H
2004-01-01
The rapidly increasing rate at which biological data is being produced requires a corresponding growth in relational databases and associated tools that can help laboratories contend with that data. With this need in mind, we describe here a Modular Approach to a Genomic, Integrated and Comprehensive (MAGIC) Database. This Oracle 9i database derives from an initial focus in our laboratory on gene discovery via production and analysis of expressed sequence tags (ESTs), and subsequently on gene expression as assessed by both EST clustering and microarrays. The MAGIC Gene Discovery portion of the database focuses on information derived from DNA sequences and on its biological relevance. In addition to MAGIC SEQ-LIMS, which is designed to support activities in the laboratory, it contains several additional subschemas. The latter include MAGIC Admin for database administration, MAGIC Sequence for sequence processing as well as sequence and clone attributes, MAGIC Cluster for the results of EST clustering, MAGIC Polymorphism in support of microsatellite and single-nucleotide-polymorphism discovery, and MAGIC Annotation for electronic annotation by BLAST and BLAT. The MAGIC Microarray portion is a MIAME-compliant database with two components at present. These are MAGIC Array-LIMS, which makes possible remote entry of all information into the database, and MAGIC Array Analysis, which provides data mining and visualization. Because all aspects of interaction with the MAGIC Database are via a web browser, it is ideally suited not only for individual research laboratories but also for core facilities that serve clients at any distance.
Hänchen, Anne; Rausch, Saskia; Landmann, Benjamin; Toti, Luigi; Nusser, Antje; Süssmuth, Roderich D
2013-03-18
The antibiotic feglymycin is a linear 13-mer peptide synthesized by the bacterium Streptomyces sp. DSM 11171. It mainly consists of the nonproteinogenic amino acids 4-hydroxyphenylglycine and 3,5-dihydroxyphenylglycine. An alanine scan of feglymycin was performed by solution-phase peptide synthesis in order to assess the significance of individual amino acid side chains for biological activity. Hence, 13 peptides were synthesized from di- and tripeptide building blocks, and subsequently tested for antibacterial activity against Staphylococcus aureus strains. Furthermore we tested the inhibition of peptidoglycan biosynthesis enzymes MurA and MurC, which are inhibited by feglymycin. Whereas the antibacterial activity is significantly based on the three amino acids D-Hpg1, L-Hpg5, and L-Phe12, the inhibitory activity against MurA and MurC depends mainly on L-Asp13. The difference in the position dependence for antibacterial activity and enzyme inhibition suggests multiple molecular targets in the modes of action of feglymycin. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Hiraishi, Tomohiro
2016-02-01
Thermally synthesized poly(aspartic acid) (tPAA) is a bio-based, biocompatible, biodegradable, and water-soluble polymer that has a high proportion of β-Asp units and equivalent moles of D- and L-Asp units. Poly(aspartic acid) (PAA) hydrolase-1 and hydrolase-2 are tPAA biodegradation enzymes purified from Gram-negative bacteria. PAA hydrolase-1 selectively cleaves amide bonds between β-Asp units via an endo-type process, whereas PAA hydrolase-2 catalyzes the exo-type hydrolysis of the products of tPAA hydrolysis by PAA hydrolase-1. The novel reactivity of PAA hydrolase-1 makes it a good candidate for a biocatalyst in β-peptide synthesis. This mini-review gives an overview of PAA hydrolases with emphasis on their biochemical and functional properties, in particular, PAA hydrolase-1. Functionally related enzymes, such as poly(R-3-hydroxybutyrate) depolymerases and β-aminopeptidases, are compared to PAA hydrolases. This mini-review also provides findings that offer an insight into the catalytic mechanisms of PAA hydrolase-1 from Pedobacter sp. KP-2.
Structure and software tools of AIDA.
Duisterhout, J S; Franken, B; Witte, F
1987-01-01
AIDA consists of a set of software tools to allow for fast development and easy-to-maintain Medical Information Systems. AIDA supports all aspects of such a system both during development and operation. It contains tools to build and maintain forms for interactive data entry and on-line input validation, a database management system including a data dictionary and a set of run-time routines for database access, and routines for querying the database and output formatting. Unlike an application generator, the user of AIDA may select parts of the tools to fulfill his needs and program other subsystems not developed with AIDA. The AIDA software uses as host language the ANSI-standard programming language MUMPS, an interpreted language embedded in an integrated database and programming environment. This greatly facilitates the portability of AIDA applications. The database facilities supported by AIDA are based on a relational data model. This data model is built on top of the MUMPS database, the so-called global structure. This relational model overcomes the restrictions of the global structure regarding string length. The global structure is especially powerful for sorting purposes. Using MUMPS as a host language allows the user an easy interface between user-defined data validation checks or other user-defined code and the AIDA tools. AIDA has been designed primarily for prototyping and for the construction of Medical Information Systems in a research environment which requires a flexible approach. The prototyping facility of AIDA operates terminal independent and is even to a great extent multi-lingual. Most of these features are table-driven; this allows on-line changes in the use of terminal type and language, but also causes overhead. AIDA has a set of optimizing tools by which it is possible to build a faster, but (of course) less flexible code from these table definitions. By separating the AIDA software in a source and a run-time version, one is able to write implementation-specific code which can be selected and loaded by a special source loader, being part of the AIDA software. This feature is also accessible for maintaining software on different sites and on different installations.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Malone, R.; Wang, X.J.
BY WRITING BOTH A CUSTOM WINDOWS(NTTM) DYNAMIC LINK LIBRARY AND GENERIC COMPANION SERVER SOFTWARE, THE INTRINSIC FUNCTIONS OF MATHSOFT MATHCAD(TM) HAVE BEEN EXTENDED WITH NEW CAPABILITIES WHICH PERMIT DIRECT ACCESS TO THE CONTROL SYSTEM DATABASES OF BROOKHAVEN NATIONAL LABORATORY ACCELERATOR TEST FACILITY. UNDER THIS SCHEME, A MATHCAD WORKSHEET EXECUTING ON A PERSONAL COMPUTER BECOMES A CLIENT WHICH CAN BOTH IMPORT AND EXPORT DATA TO A CONTROL SYSTEM SERVER VIA A NETWORK STREAM SOCKET CONNECTION. THE RESULT IS AN ALTERNATIVE, MATHEMATICALLY ORIENTED VIEW OF CONTROLLING THE ACCELERATOR INTERACTIVELY.
NASA Technical Reports Server (NTRS)
1986-01-01
Lockheed Missiles and Space Company's conceptual designs and programmatics for a Space Station Nonhuman Life Sciences Research Facility (LSRF) are presented. Conceptual designs and programmatics encompass an Initial Orbital Capability (IOC) LSRF, a growth or follow-on Orbital Capability (FOC), and the transitional process required to modify the IOC LSFR to the FOC LSFR. The IOC and FOC LSFRs correspond to missions SAAX0307 and SAAX0302 of the Space Station Mission Requirements Database, respectively.
Linking Publications to Instruments, Field Campaigns, Sites and Working Groups: The ARM Experience
NASA Astrophysics Data System (ADS)
Lehnert, K.; Parsons, M. A.; Ramachandran, R.; Fils, D.; Narock, T.; Fox, P. A.; Troyan, D.; Cialella, A. T.; Gregory, L.; Lazar, K.; Liang, M.; Ma, L.; Tilp, A.; Wagener, R.
2017-12-01
For the past 25 years, the ARM Climate Research Facility - a US Department of Energy scientific user facility - has been collecting atmospheric data in different climatic regimes using both in situ and remote instrumentation. Configuration of the facility's components has been designed to improve the understanding and representation, in climate and earth system models, of clouds and aerosols. Placing a premium on long-term continuous data collection resulted in terabytes of data having been collected, stored, and made accessible to any interested person. All data is accessible via the ARM.gov website and the ARM Data Discovery Tool. A team of metadata professionals assign appropriate tags to help facilitate searching the databases for desired data. The knowledge organization tools and concepts are used to create connections between data, instruments, field campaigns, sites, and measurements are familiar to informatics professionals. Ontology, taxonomy, classification, and thesauri are among the customized concepts put into practice for ARM's purposes. In addition to the multitude of data available, there have been approximately 3,000 journal articles that utilize ARM data. These have been linked to specific ARM web pages. Searches of the complete ARM publication database can be done using a separate interface. This presentation describes how ARM data is linked to instruments, sites, field campaigns, and publications through the application of standard knowledge organization tools and concepts.
REDIdb: an upgraded bioinformatics resource for organellar RNA editing sites.
Picardi, Ernesto; Regina, Teresa M R; Verbitskiy, Daniil; Brennicke, Axel; Quagliariello, Carla
2011-03-01
RNA editing is a post-transcriptional molecular process whereby the information in a genetic message is modified from that in the corresponding DNA template by means of nucleotide substitutions, insertions and/or deletions. It occurs mostly in organelles by clade-specific diverse and unrelated biochemical mechanisms. RNA editing events have been annotated in primary databases as GenBank and at more sophisticated level in the specialized databases REDIdb, dbRES and EdRNA. At present, REDIdb is the only freely available database that focuses on the organellar RNA editing process and annotates each editing modification in its biological context. Here we present an updated and upgraded release of REDIdb with a web-interface refurbished with graphical and computational facilities that improve RNA editing investigations. Details of the REDIdb features and novelties are illustrated and compared to other RNA editing databases. REDIdb is freely queried at http://biologia.unical.it/py_script/REDIdb/. Copyright © 2010 Elsevier B.V. and Mitochondria Research Society. All rights reserved.
NASA Astrophysics Data System (ADS)
Bagnasco, S.; Berzano, D.; Guarise, A.; Lusso, S.; Masera, M.; Vallero, S.
2015-12-01
The INFN computing centre in Torino hosts a private Cloud, which is managed with the OpenNebula cloud controller. The infrastructure offers Infrastructure-as-a-Service (IaaS) and Platform-as-a-Service (PaaS) services to different scientific computing applications. The main stakeholders of the facility are a grid Tier-2 site for the ALICE collaboration at LHC, an interactive analysis facility for the same experiment and a grid Tier-2 site for the BESIII collaboration, plus an increasing number of other small tenants. The dynamic allocation of resources to tenants is partially automated. This feature requires detailed monitoring and accounting of the resource usage. We set up a monitoring framework to inspect the site activities both in terms of IaaS and applications running on the hosted virtual instances. For this purpose we used the ElasticSearch, Logstash and Kibana (ELK) stack. The infrastructure relies on a MySQL database back-end for data preservation and to ensure flexibility to choose a different monitoring solution if needed. The heterogeneous accounting information is transferred from the database to the ElasticSearch engine via a custom Logstash plugin. Each use-case is indexed separately in ElasticSearch and we setup a set of Kibana dashboards with pre-defined queries in order to monitor the relevant information in each case. For the IaaS metering, we developed sensors for the OpenNebula API. The IaaS level information gathered through the API is sent to the MySQL database through an ad-hoc developed RESTful web service. Moreover, we have developed a billing system for our private Cloud, which relies on the RabbitMQ message queue for asynchronous communication to the database and on the ELK stack for its graphical interface. The Italian Grid accounting framework is also migrating to a similar set-up. Concerning the application level, we used the Root plugin TProofMonSenderSQL to collect accounting data from the interactive analysis facility. The BESIII virtual instances used to be monitored with Zabbix, as a proof of concept we also retrieve the information contained in the Zabbix database. In this way we have achieved a uniform monitoring interface for both the IaaS and the scientific applications, mostly leveraging off-the-shelf tools. At present, we are working to define a model for monitoring-as-a-service, based on the tools described above, which the Cloud tenants can easily configure to suit their specific needs.
Tuberculosis in the workplace: OSHA's compliance experience.
McDiarmid, M; Gamponia, M J; Ryan, M A; Hirshon, J M; Gillen, N A; Cox, M
1996-03-01
Inspections of 272 facilities were performed between May 1992 and October 1994 to determine compliance with applicable Occupational Safety and Health Administration (OSHA) requirements for prevention of tuberculosis (TB) transmission. Retrospective record review of two data sources: (1) OSHA's Computerized Integrated Management Information System and (2) an inspector-completed questionnaire on inspection results. Inspections of five types of facilities: healthcare institutions, correctional facilities, homeless shelters, long-term-care facilities for the elderly, and others, including drug treatment centers that the Centers for Disease Control and Prevention (CDC) identified as having a higher than expected rate of TB. The OSHA Compliance Memorandum, based on the 1990 CDC Guidelines, which outlined elements of a TB prevention program, was used in performing 272 inspections of facilities between May 1992 and October 1994. Elements of compliance were recorded and reviewed from the IMIS database and inspectors' questionnaires. Regulated facilities were not fully compliant with OSHA guidance. Generally, healthcare facilities performed better than other facilities. Most facilities (79%) were compliant with administrative elements of a comprehensive TB control program, such as early identification of known or suspected infectious TB patients and skin testing of workers. Only 29% of inspected facilities were found to have acceptable respiratory protection programs for the prevention of occupational TB. Facilities have not been fully compliant with the OSHA memorandum describing protection of workers from TB. Facility compliance was better with some traditionally recognized TB infection control elements, but was weaker in the area of respiratory protection programs. This may reflect a lack of familiarity with the latter type of hazard protection.
Using Quasi-Horizontal Alignment in the absence of the actual alignment.
Banihashemi, Mohamadreza
2016-10-01
Horizontal alignment is a major roadway characteristic used in safety and operational evaluations of many facility types. The Highway Safety Manual (HSM) uses this characteristic in crash prediction models for rural two-lane highways, freeway segments, and freeway ramps/C-D roads. Traffic simulation models use this characteristic in their processes on almost all types of facilities. However, a good portion of roadway databases do not include horizontal alignment data; instead, many contain point coordinate data along the roadways. SHRP 2 Roadway Information Database (RID) is a good example of this type of data. Only about 5% of this geodatabase contains alignment information and for the rest, point data can easily be produced. Even though the point data can be used to extract actual horizontal alignment data but, extracting horizontal alignment is a cumbersome and costly process, especially for a database of miles and miles of highways. This research introduces a so called "Quasi-Horizontal Alignment" that can be produced easily and automatically from point coordinate data and can be used in the safety and operational evaluations of highways. SHRP 2 RID for rural two-lane highways in Washington State is used in this study. This paper presents a process through which Quasi-Horizontal Alignments are produced from point coordinates along highways by using spreadsheet software such as MS EXCEL. It is shown that the safety and operational evaluations of the highways with Quasi-Horizontal Alignments are almost identical to the ones with the actual alignments. In the absence of actual alignment the Quasi-Horizontal Alignment can easily be produced from any type of databases that contain highway coordinates such geodatabases and digital maps. Copyright © 2016 Elsevier Ltd. All rights reserved.
Deslich, Stacie Anne; Thistlethwaite, Timothy; Coustasse, Alberto
2013-01-01
It is unclear if telepsychiatry, a subset of telemedicine, increases access to mental health care for inmates in correctional facilities or decreases costs for clinicians or facility administrators. The purpose of this investigation was to determine how utilization of telepsychiatry affected access to care and costs of providing mental health care in correctional facilities. A literature review complemented by a semistructured interview with a telepsychiatry practitioner. Five electronic databases, the National Bureau of Justice, and the American Psychiatric Association Web sites were searched for this research, and 49 sources were referenced. The literature review examined implementation of telepsychiatry in correctional facilities in Arizona, California, Georgia, Kansas, Ohio, Texas, and West Virginia to determine the effect of telepsychiatry on inmate access to mental health services and the costs of providing mental health care in correctional facilities. Telepsychiatry provided improved access to mental health services for inmates, and this increase in access is through the continuum of mental health care, which has been instrumental in increasing quality of care for inmates. Use of telepsychiatry saved correctional facilities from $12,000 to more than $1 million. The semistructured interview with the telepsychiatry practitioner supported utilization of telepsychiatry to increase access and lower costs of providing mental health care in correctional facilities. Increasing access to mental health care for this underserved group through telepsychiatry may improve living conditions and safety inside correctional facilities. Providers, facilities, and state and federal governments can expect increased savings with utilization of telepsychiatry.
Castle, Nicholas; Olson, Doug; Shah, Urvi; Hansen, Kevin
2016-09-01
This study explores the relationship between recipients of an association-sponsored Quality Award Program and select measures of quality in U.S. nursing facilities, examined both cross-sectionally and over time. Data used came from Quality Award Program recipients over 9 years (2003-2011) and a set of quality indicators from the Online Survey Certification and Reporting (OSCAR) database. These data were analyzed using a variety of multivariate regression techniques. Cross-sectionally, the award recipients demonstrated higher performance on most of the quality indicators, compared with both the broader field of nursing facilities and also a more stringent comparison group of facilities. Comparing quality from the 4 years before the award was received to the 4 years after the award, the majority of quality indicators demonstrated improvement in those facilities receiving an award. These results indicate that, in general, the nursing facilities that participate in and receive the Silver or Gold American Health Care Association (AHCA) and National Center for Assisted Living (NCAL) National Quality Award perform at a higher level of quality for residents and sustain that heightened performance over a period of time.
Murphy, Colin T; Galloway, Thomas J; Handorf, Elizabeth A; Wang, Lora; Mehra, Ranee; Flieder, Douglas B; Ridge, John A
2015-04-15
The objective of this study was to identify trends and predictors of the time to treatment initiation (TTI) for patients with head and neck squamous cell carcinoma (HNSCC). The National Cancer Database (NCDB) was reviewed for the following head and neck cancer sites: oral tongue, oropharynx, larynx, and hypopharynx. TTI was defined as the number of days from diagnosis to the initiation of definitive treatment and was measured according to covariates. Significant differences in the median TTI across each covariate were measured using the Kruskal-Wallis test, and the Spearman test was used to measure trends within covariates. For multivariate analysis, a zero-inflated, negative, binomial regression model was used to estimate the expected TTI, which was expressed in the predicted number of days; and the Vuong test was used to identify the predictors of TTI. In total, 274,630 patients were included. Between 1998 and 2011, the median TTI for all patients was 26 days, and it increased from 19 days to 30 days (P < .0001). Treatment with chemoradiation (CRT) (P < .0001), treatment at academic facilities (P < .0001), and stage IV disease (P < .0001) were associated with increased TTI. TTI significantly increased for each disease stage (P < .0001), treatment modality (P < .0001), and facility type (P < .0001) over time. In addition, patients became more likely to transition care between facilities after diagnosis for treatment initiation (P < .0001) over time. On multivariate analysis, treatment at academic facilities (33 days), transitioning care (37 days), and receipt of CRT (39 days) predicted for a longer TTI. TTI is rising for patients with HNSCC. Those who have advanced-stage disease, receive treatment with CRT, are treated at academic facilities, and who have a transition in care realized the greatest increases in TTI. © 2014 American Cancer Society.
HANFORD FACILITY ANNUAL DANGEROUS WASTE REPORT CY2005
DOE Office of Scientific and Technical Information (OSTI.GOV)
SKOLRUD, J.O.
2006-02-15
The Hanford Facility Annual Dangerous Waste Report (ADWR) is prepared to meet the requirements of Washington Administrative Code Sections 173-303-220, Generator Reporting, and 173-303-390, Facility Reporting. In addition, the ADWR is required to meet Hanford Facility RCR4 Permit Condition I.E.22, Annual Reporting. The ADWR provides summary information on dangerous waste generation and management activities for the Calendar Year for the Hanford Facility EPA ID number assigned to the Department of Energy for RCRA regulated waste, as well as Washington State only designated waste and radioactive mixed waste. An electronic database is utilized to collect and compile the large array ofmore » data needed for preparation of this report. Information includes details of waste generated on the Hanford Facility, waste generated offsite and sent to Hanford for management, and other waste management activities conducted at Hanford, including treatment, storage, and disposal. Report details consist of waste descriptions and weights, waste codes and designations, and waste handling codes, In addition, for waste shipped to Hanford for treatment and/or disposal, information on manifest numbers, the waste transporter, the waste receiving facility, and the original waste generators are included. In addition to paper copies, the report is also transmitted electronically to a web site maintained by the Washington State Department of Ecology.« less
Spatial modeling of potential woody biomass flow
Woodam Chung; Nathaniel Anderson
2012-01-01
The flow of woody biomass to end users is determined by economic factors, especially the amount available across a landscape and delivery costs of bioenergy facilities. The objective of this study develop methodology to quantify landscape-level stocks and potential biomass flows using the currently available spatial database road network analysis tool. We applied this...
47 CFR 90.371 - Dedicated short range communications service.
Code of Federal Regulations, 2010 CFR
2010-10-01
... Arnold AFB, TN 352250N 0860202W Tyndall AFB, FL 300412N 0853436W Charles E. Kelly Support Facility... new Federal assignment is made, the Commission's Universal Licensing System database will be updated, accordingly, to protect the new Federal assignment and the list in paragraph (b) of this section will be...
ERIC Educational Resources Information Center
Sandieson, Robert W.; Kirkpatrick, Lori C.; Sandieson, Rachel M.; Zimmerman, Walter
2010-01-01
Digital technologies enable the storage of vast amounts of information, accessible with remarkable ease. However, along with this facility comes the challenge to find pertinent information from the volumes of nonrelevant information. The present article describes the pearl-harvesting methodological framework for information retrieval. Pearl…
The VERITAS Facility: A Virtual Environment Platform for Human Performance Research
2016-01-01
IAE The IAE supports the audio environment that users experience during the course of an experiment. This includes environmental sounds, user-to...future, we are looking towards a database-based system that would use MySQL or an equivalent product to store the large data sets and provide standard
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bush, Brian W; Brunhart-Lupo, Nicholas J; Gruchalla, Kenny M
This brochure describes a system dynamics simulation (SD) framework that supports an end-to-end analysis workflow that is optimized for deployment on ESIF facilities(Peregrine and the Insight Center). It includes (I) parallel and distributed simulation of SD models, (ii) real-time 3D visualization of running simulations, and (iii) comprehensive database-oriented persistence of simulation metadata, inputs, and outputs.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bush, Brian W; Brunhart-Lupo, Nicholas J; Gruchalla, Kenny M
This presentation describes a system dynamics simulation (SD) framework that supports an end-to-end analysis workflow that is optimized for deployment on ESIF facilities(Peregrine and the Insight Center). It includes (I) parallel and distributed simulation of SD models, (ii) real-time 3D visualization of running simulations, and (iii) comprehensive database-oriented persistence of simulation metadata, inputs, and outputs.
ERIC Educational Resources Information Center
Cedeno, David L.; Jones, Marjorie A.; Friesen, Jon A.; Wirtz, Mark W.; Rios, Luz Amalia; Ocampo, Gonzalo Taborda
2010-01-01
At the Universidad de Caldas, Manizales, Colombia, we used their new computer facilities to introduce chemistry graduate students to biochemical database mining and quantum chemistry calculations using freeware. These hands-on workshops allowed the students a strong introduction to easily accessible software and how to use this software to begin…
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-31
... factors as the approved models, are validated by experimental test data, and receive the Administrator's... stage of the MEP involves applying the model against a database of experimental test cases including..., particularly the requirement for validation by experimental test data. That guidance is based on the MEP's...
The purpose of this report is to assess the application of tools to community-level assessments of exposure, health and the environment. Various tools and datasets provided different types of information, such as on health effects, chemical types and volumes, facility locations a...
Using Spreadsheets to Teach Statistics in Geography.
ERIC Educational Resources Information Center
Lee, M. P.; Soper, J. B.
1987-01-01
Maintains that teaching methods of statistical calculation in geography may be enhanced by using a computer spreadsheet. The spreadsheet format of rows and columns allows the data to be inspected and altered to demonstrate various statistical properties. The inclusion of graphics and database facilities further adds to the value of a spreadsheet.…
MMpI: A WideRange of Available Compounds of Matrix Metalloproteinase Inhibitors
Muvva, Charuvaka; Patra, Sanjukta; Venkatesan, Subramanian
2016-01-01
Matrix metalloproteinases (MMPs) are a family of zinc-dependent proteinases involved in the regulation of the extracellular signaling and structural matrix environment of cells and tissues. MMPs are considered as promising targets for the treatment of many diseases. Therefore, creation of database on the inhibitors of MMP would definitely accelerate the research activities in this area due to its implication in above-mentioned diseases and associated limitations in the first and second generation inhibitors. In this communication, we report the development of a new MMpI database which provides resourceful information for all researchers working in this field. It is a web-accessible, unique resource that contains detailed information on the inhibitors of MMP including small molecules, peptides and MMP Drug Leads. The database contains entries of ~3000 inhibitors including ~72 MMP Drug Leads and ~73 peptide based inhibitors. This database provides the detailed molecular and structural details which are necessary for the drug discovery and development. The MMpI database contains physical properties, 2D and 3D structures (mol2 and pdb format files) of inhibitors of MMP. Other data fields are hyperlinked to PubChem, ChEMBL, BindingDB, DrugBank, PDB, MEROPS and PubMed. The database has extensive searching facility with MMpI ID, IUPAC name, chemical structure and with the title of research article. The MMP inhibitors provided in MMpI database are optimized using Python-based Hierarchical Environment for Integrated Xtallography (Phenix) software. MMpI Database is unique and it is the only public database that contains and provides the complete information on the inhibitors of MMP. Database URL: http://clri.res.in/subramanian/databases/mmpi/index.php. PMID:27509041
Anomaly detection applied to a materials control and accounting database
DOE Office of Scientific and Technical Information (OSTI.GOV)
Whiteson, R.; Spanks, L.; Yarbro, T.
An important component of the national mission of reducing the nuclear danger includes accurate recording of the processing and transportation of nuclear materials. Nuclear material storage facilities, nuclear chemical processing plants, and nuclear fuel fabrication facilities collect and store large amounts of data describing transactions that involve nuclear materials. To maintain confidence in the integrity of these data, it is essential to identify anomalies in the databases. Anomalous data could indicate error, theft, or diversion of material. Yet, because of the complex and diverse nature of the data, analysis and evaluation are extremely tedious. This paper describes the authors workmore » in the development of analysis tools to automate the anomaly detection process for the Material Accountability and Safeguards System (MASS) that tracks and records the activities associated with accountable quantities of nuclear material at Los Alamos National Laboratory. Using existing guidelines that describe valid transactions, the authors have created an expert system that identifies transactions that do not conform to the guidelines. Thus, this expert system can be used to focus the attention of the expert or inspector directly on significant phenomena.« less
NASA Technical Reports Server (NTRS)
Mejzak, R. S.
1980-01-01
The distributed processing concept is defined in terms of control primitives, variables, and structures and their use in performing a decomposed discrete Fourier transform (DET) application function. The design assumes interprocessor communications to be anonymous. In this scheme, all processors can access an entire common database by employing control primitives. Access to selected areas within the common database is random, enforced by a hardware lock, and determined by task and subtask pointers. This enables the number of processors to be varied in the configuration without any modifications to the control structure. Decompositional elements of the DFT application function in terms of tasks and subtasks are also described. The experimental hardware configuration consists of IMSAI 8080 chassis which are independent, 8 bit microcomputer units. These chassis are linked together to form a multiple processing system by means of a shared memory facility. This facility consists of hardware which provides a bus structure to enable up to six microcomputers to be interconnected. It provides polling and arbitration logic so that only one processor has access to shared memory at any one time.
NASA Astrophysics Data System (ADS)
Cole, Ryan Kenneth; Schroeder, Paul James; Diego Draper, Anthony; Rieker, Gregory Brian
2018-06-01
Modelling absorption spectra in high pressure, high temperature environments is complicated by the increased relevance of higher order collisional phenomena (e.g. line mixing, collision-induced absorption, finite duration of collisions) that alter the spectral lineshape. Accurate reference spectroscopy in these conditions is of interest for mineralogy and radiative transfer studies of Venus as well as other dense planetary atmospheres. We present a new, high pressure, high temperature absorption spectroscopy facility at the University of Colorado Boulder. This facility employs a dual frequency comb absorption spectrometer to record broadband (500nm), high resolution (~0.002nm) spectra in conditions comparable to the Venus surface (730K, 90bar). Measurements of the near-infrared spectrum of carbon dioxide at high pressure and temperature will be compared to modeled spectra extrapolated from the HITRAN 2016 database as well as other published models that include additional collisional physics. This comparison gives insight into the effectiveness of existing absorption databases for modeling the lower Venus atmosphere as well as the need to expand absorption models to suit these conditions.
[Quality Indicators of Primary Health Care Facilities in Austria].
Semlitsch, Thomas; Abuzahra, Muna; Stigler, Florian; Jeitler, Klaus; Posch, Nicole; Siebenhofer, Andrea
2017-07-11
Background The strengthening of primary health care is one major goal of the current national health reform in Austria. In this context, a new interdisciplinary concept was developed in 2014 that defines structures and requirements for future primary health care facilities. Objective The aim of this project was the development of quality indicators for the evaluation of the scheduled primary health care facilities in Austria, which are in accordance with the new Austrian concept. Methods We used the RAND/NPCRDC method for the development and selection of the quality indicators. We conducted systematic literature searches for existing measures in international databases for quality indicators as well as in bibliographic databases. All retrieved measures were evaluated and rated by an expert panel in a 2-step process regarding relevance and feasibility. Results Overall, the literature searches yielded 281 potentially relevant quality indicators, which were summarized to 65 different quality measures for primary health care. Out of these, the panel rated and accepted 30 measures as relevant and feasible for use in Austria. Five of these indicators were structure measures, 14 were process measures and the remaining 11 were outcome measures. Based on the Austrian primary health care concept, the final set of quality indicators was grouped in the 5 following domains: Access to primary health care (5), quality of care (15), continuity of care (5), coordination of care (4), and safety (1). Conclusion This set of quality measures largely covers the four defined functions of primary health care. It enables standardized evaluation of primary health care facilities in Austria regarding the implementation of the Austrian primary health care concept as well as improvement in healthcare of the population. © Georg Thieme Verlag KG Stuttgart · New York.
Building information models for astronomy projects
NASA Astrophysics Data System (ADS)
Ariño, Javier; Murga, Gaizka; Campo, Ramón; Eletxigerra, Iñigo; Ampuero, Pedro
2012-09-01
A Building Information Model is a digital representation of physical and functional characteristics of a building. BIMs represent the geometrical characteristics of the Building, but also properties like bills of quantities, definition of COTS components, status of material in the different stages of the project, project economic data, etc. The BIM methodology, which is well established in the Architecture Engineering and Construction (AEC) domain for conventional buildings, has been brought one step forward in its application for Astronomical/Scientific facilities. In these facilities steel/concrete structures have high dynamic and seismic requirements, M&E installations are complex and there is a large amount of special equipment and mechanisms involved as a fundamental part of the facility. The detail design definition is typically implemented by different design teams in specialized design software packages. In order to allow the coordinated work of different engineering teams, the overall model, and its associated engineering database, is progressively integrated using a coordination and roaming software which can be used before starting construction phase for checking interferences, planning the construction sequence, studying maintenance operation, reporting to the project office, etc. This integrated design & construction approach will allow to efficiently plan construction sequence (4D). This is a powerful tool to study and analyze in detail alternative construction sequences and ideally coordinate the work of different construction teams. In addition engineering, construction and operational database can be linked to the virtual model (6D), what gives to the end users a invaluable tool for the lifecycle management, as all the facility information can be easily accessed, added or replaced. This paper presents the BIM methodology as implemented by IDOM with the E-ELT and ATST Enclosures as application examples.
Wu, Meng-Hsuan; Wu, Meng-Ju; Chou, Li-Fang
2014-01-01
Doctor shopping is a common phenomenon in many countries. However, patterns of switching healthcare facilities on the same day were little known. The data were obtained from the longitudinal cohort datasets (LHID2010) of Taiwan's National Health Insurance Research Database in 2010. Of 1,000,000 persons of the cohort with 13,276,928 nonemergent visits, 185,347 patients had visited different healthcare facilities within one day, with a total of 672,478 visits and 337,260 switches between facilities in 329,073 patient-days. While 63.0% (n = 212,590) of all switches occurred between facilities of the same accreditation level, 14.1% (n = 47,664) moved from lower to higher level, and 22.8% (n = 77,006) moved in the opposite direction. In 33,689 switches, patients moved to the same specialty of another facility. In 48,324 switches, patients moved to another facility with the same diagnosis, and the most frequent diagnoses were diseases of the digestive system (11,148) and diseases of the respiratory system (10,393). In a densely populated country without strict referral regulation, a high percentage of Taiwanese people had the experience of visiting different healthcare facilities on the same day. The system of family physicians as personal doctors and gatekeepers to healthcare might ameliorate the harmful impact. PMID:24892063
Wu, Meng-Hsuan; Wu, Meng-Ju; Chou, Li-Fang; Chen, Tzeng-Ji
2014-01-01
Doctor shopping is a common phenomenon in many countries. However, patterns of switching healthcare facilities on the same day were little known. The data were obtained from the longitudinal cohort datasets (LHID2010) of Taiwan's National Health Insurance Research Database in 2010. Of 1,000,000 persons of the cohort with 13,276,928 nonemergent visits, 185,347 patients had visited different healthcare facilities within one day, with a total of 672,478 visits and 337,260 switches between facilities in 329,073 patient-days. While 63.0% (n = 212,590) of all switches occurred between facilities of the same accreditation level, 14.1% (n = 47,664) moved from lower to higher level, and 22.8% (n = 77,006) moved in the opposite direction. In 33,689 switches, patients moved to the same specialty of another facility. In 48,324 switches, patients moved to another facility with the same diagnosis, and the most frequent diagnoses were diseases of the digestive system (11,148) and diseases of the respiratory system (10,393). In a densely populated country without strict referral regulation, a high percentage of Taiwanese people had the experience of visiting different healthcare facilities on the same day. The system of family physicians as personal doctors and gatekeepers to healthcare might ameliorate the harmful impact.
Refurbishment and Automation of the Thermal/Vacuum Facilities at the Goddard Space Flight Center
NASA Technical Reports Server (NTRS)
Donohue, John T.; Johnson, Chris; Ogden, Rick; Sushon, Janet
1998-01-01
The thermal/vacuum facilities located at the Goddard Space Flight Center (GSFC) have supported both manned and unmanned space flight since the 1960s. Of the 11 facilities, currently 10 of the systems are scheduled for refurbishment and/or replacement as part of a 5-year implementation. Expected return on investment includes the reduction in test schedules, improvements in the safety of facility operations, reduction in the complexity of a test and the reduction in personnel support required for a test. Additionally, GSFC will become a global resource renowned for expertise in thermal engineering, mechanical engineering and for the automation of thermal/vacuum facilities and thermal/vacuum tests. Automation of the thermal/vacuum facilities includes the utilization of Programmable Logic Controllers (PLCs) and the use of Supervisory Control and Data Acquisition (SCADA) systems. These components allow the computer control and automation of mechanical components such as valves and pumps. In some cases, the chamber and chamber shroud require complete replacement while others require only mechanical component retrofit or replacement. The project of refurbishment and automation began in 1996 and has resulted in the computer control of one Facility (Facility #225) and the integration of electronically controlled devices and PLCs within several other facilities. Facility 225 has been successfully controlled by PLC and SCADA for over one year. Insignificant anomalies have occurred and were resolved with minimal impact to testing and operations. The amount of work remaining to be performed will occur over the next four to five years. Fiscal year 1998 includes the complete refurbishment of one facility, computer control of the thermal systems in two facilities, implementation of SCADA and PLC systems to support multiple facilities and the implementation of a Database server to allow efficient test management and data analysis.
Detecting errors and anomalies in computerized materials control and accountability databases
DOE Office of Scientific and Technical Information (OSTI.GOV)
Whiteson, R.; Hench, K.; Yarbro, T.
The Automated MC and A Database Assessment project is aimed at improving anomaly and error detection in materials control and accountability (MC and A) databases and increasing confidence in the data that they contain. Anomalous data resulting in poor categorization of nuclear material inventories greatly reduces the value of the database information to users. Therefore it is essential that MC and A data be assessed periodically for anomalies or errors. Anomaly detection can identify errors in databases and thus provide assurance of the integrity of data. An expert system has been developed at Los Alamos National Laboratory that examines thesemore » large databases for anomalous or erroneous data. For several years, MC and A subject matter experts at Los Alamos have been using this automated system to examine the large amounts of accountability data that the Los Alamos Plutonium Facility generates. These data are collected and managed by the Material Accountability and Safeguards System, a near-real-time computerized nuclear material accountability and safeguards system. This year they have expanded the user base, customizing the anomaly detector for the varying requirements of different groups of users. This paper describes the progress in customizing the expert systems to the needs of the users of the data and reports on their results.« less
No Evidence of Isomerism for the First Excited State of {sup 93}Rb
DOE Office of Scientific and Technical Information (OSTI.GOV)
Miernik, K., E-mail: kmiernik@fuw.edu.pl; Gross, C.J.; Grzywacz, R.
2014-06-15
The 253.3–keV excited state located in {sup 93}Rb was studied at the Holifield Radioactive Ion Beam Facility in Oak Ridge. This state, described as isomeric in databases, was populated in the decay of {sup 93}Kr produced by proton–induced fission of {sup 238}U and isolated using the isotope separation on–line technique. We report that the 253.3–keV level does not reveal isomerism and the upper limit of the half-life from our measurement is 4 ns. Our findings are supported by previously reported results that were not taken into account in the latest nuclear databases.
This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Goscinski, Wojtek J.; McIntosh, Paul; Felzmann, Ulrich; Maksimenko, Anton; Hall, Christopher J.; Gureyev, Timur; Thompson, Darren; Janke, Andrew; Galloway, Graham; Killeen, Neil E. B.; Raniga, Parnesh; Kaluza, Owen; Ng, Amanda; Poudel, Govinda; Barnes, David G.; Nguyen, Toan; Bonnington, Paul; Egan, Gary F.
2014-01-01
The Multi-modal Australian ScienceS Imaging and Visualization Environment (MASSIVE) is a national imaging and visualization facility established by Monash University, the Australian Synchrotron, the Commonwealth Scientific Industrial Research Organization (CSIRO), and the Victorian Partnership for Advanced Computing (VPAC), with funding from the National Computational Infrastructure and the Victorian Government. The MASSIVE facility provides hardware, software, and expertise to drive research in the biomedical sciences, particularly advanced brain imaging research using synchrotron x-ray and infrared imaging, functional and structural magnetic resonance imaging (MRI), x-ray computer tomography (CT), electron microscopy and optical microscopy. The development of MASSIVE has been based on best practice in system integration methodologies, frameworks, and architectures. The facility has: (i) integrated multiple different neuroimaging analysis software components, (ii) enabled cross-platform and cross-modality integration of neuroinformatics tools, and (iii) brought together neuroimaging databases and analysis workflows. MASSIVE is now operational as a nationally distributed and integrated facility for neuroinfomatics and brain imaging research. PMID:24734019
NASA Astrophysics Data System (ADS)
Tynan, M. C.; Russell, G. P.; Perry, F.; Kelley, R.; Champenois, S. T.
2017-12-01
This global survey presents a synthesis of some notable geotechnical and engineering information reflected in four interactive layer maps for selected: 1) deep mines and shafts; 2) existing, considered or planned radioactive waste management deep underground studies, sites, or disposal facilities; 3) deep large diameter boreholes, and 4) physics underground laboratories and facilities from around the world. These data are intended to facilitate user access to basic information and references regarding deep underground "facilities", history, activities, and plans. In general, the interactive maps and database [http://gis.inl.gov/globalsites/] provide each facility's approximate site location, geology, and engineered features (e.g.: access, geometry, depth, diameter, year of operations, groundwater, lithology, host unit name and age, basin; operator, management organization, geographic data, nearby cultural features, other). Although the survey is not all encompassing, it is a comprehensive review of many of the significant existing and historical underground facilities discussed in the literature addressing radioactive waste management and deep mined geologic disposal safety systems. The global survey is intended to support and to inform: 1) interested parties and decision makers; 2) radioactive waste disposal and siting option evaluations, and 3) safety case development as a communication tool applicable to any mined geologic disposal facility as a demonstration of historical and current engineering and geotechnical capabilities available for use in deep underground facility siting, planning, construction, operations and monitoring.
NASA Astrophysics Data System (ADS)
Brissebrat, Guillaume; Mastrorillo, Laurence; Ramage, Karim; Boichard, Jean-Luc; Cloché, Sophie; Fleury, Laurence; Klenov, Ludmila; Labatut, Laurent; Mière, Arnaud
2013-04-01
The international HyMeX (HYdrological cycle in the Mediterranean EXperiment) project aims at a better understanding and quantification of the hydrological cycle and related processes in the Mediterranean, with emphasis on high-impact weather events, inter-annual to decadal variability of the Mediterranean coupled system, and associated trends in the context of global change. The project includes long term monitoring of environmental parameters, intensive field campaigns, use of satellite data, modelling studies, as well as post event field surveys and value-added products processing. Therefore HyMeX database incorporates various dataset types from different disciplines, either operational or research. The database relies on a strong collaboration between OMP and IPSL data centres. Field data, which are 1D time series, maps or pictures, are managed by OMP team while gridded data (satellite products, model outputs, radar data...) are managed by IPSL team. At present, the HyMeX database contains about 150 datasets, including 80 hydrological, meteorological, ocean and soil in situ datasets, 30 radar datasets, 15 satellite products, 15 atmosphere, ocean and land surface model outputs from operational (re-)analysis or forecasts and from research simulations, and 5 post event survey datasets. The data catalogue complies with international standards (ISO 19115; INSPIRE; Directory Interchange Format; Global Change Master Directory Thesaurus). It includes all the datasets stored in the HyMeX database, as well as external datasets relevant for the project. All the data, whatever the type is, are accessible through a single gateway. The database website http://mistrals.sedoo.fr/HyMeX offers different tools: - A registration procedure which enables any scientist to accept the data policy and apply for a user database account. - A search tool to browse the catalogue using thematic, geographic and/or temporal criteria. - Sorted lists of the datasets by thematic keywords, by measured parameters, by instruments or by platform type. - Forms to document observations or products that will be provided to the database. - A shopping-cart web interface to order in situ data files. - Ftp facilities to access gridded data. The website will soon propose new facilities. Many in situ datasets have been homogenized and inserted in a relational database yet, in order to enable more accurate data selection and download of different datasets in a shared format. Interoperability between the two data centres will be enhanced by the OpenDAP communication protocol associated with the Thredds catalogue software, which may also be implemented in other data centres that manage data of interest for the HyMeX project. In order to meet the operational needs for the HyMeX 2012 campaigns, a day-to-day quick look and report display website has been developed too: http://sop.hymex.org. It offers a convenient way to browse meteorological conditions and data during the campaign periods.
Review of Transient Testing of Fast Reactor Fuels in the Transient REActor Test Facility (TREAT)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jensen, C.; Wachs, D.; Carmack, J.
The restart of the Transient REActor Test (TREAT) facility provides a unique opportunity to engage the fast reactor fuels community to reinitiate in-pile experimental safety studies. Historically, the TREAT facility played a critical role in characterizing the behavior of both metal and oxide fast reactor fuels under off-normal conditions, irradiating hundreds of fuel pins to support fast reactor fuel development programs. The resulting test data has provided validation for a multitude of fuel performance and severe accident analysis computer codes. This paper will provide a review of the historical database of TREAT experiments including experiment design, instrumentation, test objectives, andmore » salient findings. Additionally, the paper will provide an introduction to the current and future experiment plans of the U.S. transient testing program at TREAT.« less
National Facilities Study. Volume 1: Facilities Inventory
NASA Technical Reports Server (NTRS)
1994-01-01
The inventory activity was initiated to solve the critical need for a single source of site specific descriptive and parametric data on major public and privately held aeronautics and aerospace related facilities. This a challenging undertaking due to the scope of the effort and the short lead time in which to assemble the inventory and have it available to support the task group study needs. The inventory remains dynamic as sites are being added and the data is accessed and refined as the study progresses. The inventory activity also included the design and implementation of a computer database and analytical tools to simplify access to the data. This volume describes the steps which were taken to define the data requirements, select sites, and solicit and acquire data from them. A discussion of the inventory structure and analytical tools is also provided.
Robey, H F; Amendt, P A; Milovich, J L; Park, H-S; Hamza, A V; Bono, M J
2009-10-02
High-convergence, hohlraum-driven implosions of double-shell capsules using mid-Z (SiO2) inner shells have been performed on the OMEGA laser facility [T. R. Boehly, Opt. Commun. 133, 495 (1997)]. These experiments provide an essential extension of the results of previous low-Z (CH) double-shell implosions [P. A. Amendt, Phys. Rev. Lett. 94, 065004 (2005)] to materials of higher density and atomic number. Analytic modeling, supported by highly resolved 2D numerical simulations, is used to account for the yield degradation due to interfacial atomic mixing. This extended experimental database from OMEGA enables a validation of the mix model, and provides a means for quantitatively assessing the prospects for high-Z double-shell implosions on the National Ignition Facility [Paisner, Laser Focus World 30, 75 (1994)].
Los Alamos Plutonium Facility Waste Management System
DOE Office of Scientific and Technical Information (OSTI.GOV)
Smith, K.; Montoya, A.; Wieneke, R.
1997-02-01
This paper describes the new computer-based transuranic (TRU) Waste Management System (WMS) being implemented at the Plutonium Facility at Los Alamos National Laboratory (LANL). The Waste Management System is a distributed computer processing system stored in a Sybase database and accessed by a graphical user interface (GUI) written in Omnis7. It resides on the local area network at the Plutonium Facility and is accessible by authorized TRU waste originators, count room personnel, radiation protection technicians (RPTs), quality assurance personnel, and waste management personnel for data input and verification. Future goals include bringing outside groups like the LANL Waste Management Facilitymore » on-line to participate in this streamlined system. The WMS is changing the TRU paper trail into a computer trail, saving time and eliminating errors and inconsistencies in the process.« less
Advanced SPARQL querying in small molecule databases.
Galgonek, Jakub; Hurt, Tomáš; Michlíková, Vendula; Onderka, Petr; Schwarz, Jan; Vondrášek, Jiří
2016-01-01
In recent years, the Resource Description Framework (RDF) and the SPARQL query language have become more widely used in the area of cheminformatics and bioinformatics databases. These technologies allow better interoperability of various data sources and powerful searching facilities. However, we identified several deficiencies that make usage of such RDF databases restrictive or challenging for common users. We extended a SPARQL engine to be able to use special procedures inside SPARQL queries. This allows the user to work with data that cannot be simply precomputed and thus cannot be directly stored in the database. We designed an algorithm that checks a query against data ontology to identify possible user errors. This greatly improves query debugging. We also introduced an approach to visualize retrieved data in a user-friendly way, based on templates describing visualizations of resource classes. To integrate all of our approaches, we developed a simple web application. Our system was implemented successfully, and we demonstrated its usability on the ChEBI database transformed into RDF form. To demonstrate procedure call functions, we employed compound similarity searching based on OrChem. The application is publicly available at https://bioinfo.uochb.cas.cz/projects/chemRDF.
Experience with Multi-Tier Grid MySQL Database Service Resiliency at BNL
NASA Astrophysics Data System (ADS)
Wlodek, Tomasz; Ernst, Michael; Hover, John; Katramatos, Dimitrios; Packard, Jay; Smirnov, Yuri; Yu, Dantong
2011-12-01
We describe the use of F5's BIG-IP smart switch technology (3600 Series and Local Traffic Manager v9.0) to provide load balancing and automatic fail-over to multiple Grid services (GUMS, VOMS) and their associated back-end MySQL databases. This resiliency is introduced in front of the external application servers and also for the back-end database systems, which is what makes it "multi-tier". The combination of solutions chosen to ensure high availability of the services, in particular the database replication and fail-over mechanism, are discussed in detail. The paper explains the design and configuration of the overall system, including virtual servers, machine pools, and health monitors (which govern routing), as well as the master-slave database scheme and fail-over policies and procedures. Pre-deployment planning and stress testing will be outlined. Integration of the systems with our Nagios-based facility monitoring and alerting is also described. And application characteristics of GUMS and VOMS which enable effective clustering will be explained. We then summarize our practical experiences and real-world scenarios resulting from operating a major US Grid center, and assess the applicability of our approach to other Grid services in the future.
Payload accommodation and development planning tools - A Desktop Resource Leveling Model (DRLM)
NASA Technical Reports Server (NTRS)
Hilchey, John D.; Ledbetter, Bobby; Williams, Richard C.
1989-01-01
The Desktop Resource Leveling Model (DRLM) has been developed as a tool to rapidly structure and manipulate accommodation, schedule, and funding profiles for any kind of experiments, payloads, facilities, and flight systems or other project hardware. The model creates detailed databases describing 'end item' parameters, such as mass, volume, power requirements or costs and schedules for payload, subsystem, or flight system elements. It automatically spreads costs by calendar quarters and sums costs or accommodation parameters by total project, payload, facility, payload launch, or program phase. Final results can be saved or printed out, automatically documenting all assumptions, inputs, and defaults.
Ruttenber, A J; McCrea, J S; Wade, T D; Schonbeck, M F; LaMontagne, A D; Van Dyke, M V; Martyny, J W
2001-02-01
We outline methods for integrating epidemiologic and industrial hygiene data systems for the purpose of exposure estimation, exposure surveillance, worker notification, and occupational medicine practice. We present examples of these methods from our work at the Rocky Flats Plant--a former nuclear weapons facility that fabricated plutonium triggers for nuclear weapons and is now being decontaminated and decommissioned. The weapons production processes exposed workers to plutonium, gamma photons, neutrons, beryllium, asbestos, and several hazardous chemical agents, including chlorinated hydrocarbons and heavy metals. We developed a job exposure matrix (JEM) for estimating exposures to 10 chemical agents in 20 buildings for 120 different job categories over a production history spanning 34 years. With the JEM, we estimated lifetime chemical exposures for about 12,000 of the 16,000 former production workers. We show how the JEM database is used to estimate cumulative exposures over different time periods for epidemiological studies and to provide notification and determine eligibility for a medical screening program developed for former workers. We designed an industrial hygiene data system for maintaining exposure data for current cleanup workers. We describe how this system can be used for exposure surveillance and linked with the JEM and databases on radiation doses to develop lifetime exposure histories and to determine appropriate medical monitoring tests for current cleanup workers. We also present time-line-based graphical methods for reviewing and correcting exposure estimates and reporting them to individual workers.
Temporal Wind Pairs for Space Launch Vehicle Capability Assessment and Risk Mitigation
NASA Technical Reports Server (NTRS)
Decker, Ryan K.; Barbre, Robert E., Jr.
2015-01-01
Space launch vehicles incorporate upper-level wind assessments to determine wind effects on the vehicle and for a commit to launch decision. These assessments make use of wind profiles measured hours prior to launch and may not represent the actual wind the vehicle will fly through. Uncertainty in the winds over the time period between the assessment and launch introduces uncertainty in assessment of vehicle controllability and structural integrity that must be accounted for to ensure launch safety. Temporal wind pairs are used in engineering development of allowances to mitigate uncertainty. Five sets of temporal wind pairs at various times (0.75, 1.5, 2, 3 and 4-hrs) at the United States Air Force Eastern Range and Western Range, as well as the National Aeronautics and Space Administration's Wallops Flight Facility are developed for use in upper-level wind assessments on vehicle performance. Historical databases are compiled from balloon-based and vertically pointing Doppler radar wind profiler systems. Various automated and manual quality control procedures are used to remove unacceptable profiles. Statistical analyses on the resultant wind pairs from each site are performed to determine if the observed extreme wind changes in the sample pairs are representative of extreme temporal wind change. Wind change samples in the Eastern Range and Western Range databases characterize extreme wind change. However, the small sample sizes in the Wallops Flight Facility databases yield low confidence that the sample population characterizes extreme wind change that could occur.
Temporal Wind Pairs for Space Launch Vehicle Capability Assessment and Risk Mitigation
NASA Technical Reports Server (NTRS)
Decker, Ryan K.; Barbre, Robert E., Jr.
2014-01-01
Space launch vehicles incorporate upper-level wind assessments to determine wind effects on the vehicle and for a commit to launch decision. These assessments make use of wind profiles measured hours prior to launch and may not represent the actual wind the vehicle will fly through. Uncertainty in the winds over the time period between the assessment and launch introduces uncertainty in assessment of vehicle controllability and structural integrity that must be accounted for to ensure launch safety. Temporal wind pairs are used in engineering development of allowances to mitigate uncertainty. Five sets of temporal wind pairs at various times (0.75, 1.5, 2, 3 and 4-hrs) at the United States Air Force Eastern Range and Western Range, as well as the National Aeronautics and Space Administration's Wallops Flight Facility are developed for use in upper-level wind assessments on vehicle performance. Historical databases are compiled from balloon-based and vertically pointing Doppler radar wind profiler systems. Various automated and manual quality control procedures are used to remove unacceptable profiles. Statistical analyses on the resultant wind pairs from each site are performed to determine if the observed extreme wind changes in the sample pairs are representative of extreme temporal wind change. Wind change samples in the Eastern Range and Western Range databases characterize extreme wind change. However, the small sample sizes in the Wallops Flight Facility databases yield low confidence that the sample population characterizes extreme wind change that could occur.
Telescience Support Center Data System Software
NASA Technical Reports Server (NTRS)
Rahman, Hasan
2010-01-01
The Telescience Support Center (TSC) team has developed a databasedriven, increment-specific Data Require - ment Document (DRD) generation tool that automates much of the work required for generating and formatting the DRD. It creates a database to load the required changes to configure the TSC data system, thus eliminating a substantial amount of labor in database entry and formatting. The TSC database contains the TSC systems configuration, along with the experimental data, in which human physiological data must be de-commutated in real time. The data for each experiment also must be cataloged and archived for future retrieval. TSC software provides tools and resources for ground operation and data distribution to remote users consisting of PIs (principal investigators), bio-medical engineers, scientists, engineers, payload specialists, and computer scientists. Operations support is provided for computer systems access, detailed networking, and mathematical and computational problems of the International Space Station telemetry data. User training is provided for on-site staff and biomedical researchers and other remote personnel in the usage of the space-bound services via the Internet, which enables significant resource savings for the physical facility along with the time savings versus traveling to NASA sites. The software used in support of the TSC could easily be adapted to other Control Center applications. This would include not only other NASA payload monitoring facilities, but also other types of control activities, such as monitoring and control of the electric grid, chemical, or nuclear plant processes, air traffic control, and the like.
Rating long-term care facilities on pressure ulcer development: importance of case-mix adjustment.
Berlowitz, D R; Ash, A S; Brandeis, G H; Brand, H K; Halpern, J L; Moskowitz, M A
1996-03-15
To determine the importance of case-mix adjustment in interpreting differences in rates of pressure ulcer development in Department of Veterans Affairs long- term care facilities. A sample assembled from the Patient Assessment File, a Veterans Affairs administrative database, was used to derive predictors of pressure ulcer development; the resulting model was validated in a separate sample. Facility-level rates of pressure ulcer development, both unadjusted and adjusted for case mix using the predictive model, were compared. Department of Veterans Affairs long-term care facilities. The derivation sample consisted of 31 150 intermediate medicine and nursing home residents who were initially free of pressure ulcers and were institutionalized between October 1991 and April 1993. The validation sample consisted of 17 946 residents institutionalized from April 1993 to October 1993. Development of a stage 2 or greater pressure ulcer. 11 factors predicted pressure ulcer development. Validated performance properties of the resulting model were good. Model-predicted rates of pressure ulcer development at individual long-term care facilities varied from 1.9% to 6.3%, and observed rates ranged from 0% to 10.9%. Case-mix-adjusted rates and ranks of facilities differed considerably from unadjusted ratings. For example, among five facilities that were identified as high outliers on the basis of unadjusted rates, two remained as outliers after adjustment for case mix. Long-term care facilities differ in case mix. Adjustments for case mix result in different judgments about facility performance and should be used when facility incidence rates are compared.
Geo-Caching: Place-Based Discovery of Virginia State Parks and Museums
ERIC Educational Resources Information Center
Gray, Howard Richard
2007-01-01
The use of Global Positioning Systems (GPS) units has exploded in recent years along with the computer technology to access this data-based information. Geo-caching is an exciting game using GPS that provides place-based information regarding the public lands, facilities and cultural heritage programs within the Virginia Parks and Museum system.…
Santa Rita Experimental Range digital database: user's guide
Mitchel P. McClaran; Deborah L. Angell; Craig Wissler
2002-01-01
Long-term measurements and repeat photograph collections have been collected in a systematic manner on the approximately 21,000 ha Santa Rita Experimental Range (SRER) since its establishment in 1903. This research facility, located in the Desert Grassland vegetation of southern Arizona, was administered by the U.S. Department of Agriculture until 1988, when it was...
Factors Predicting Lawsuits against Nursing Homes in Florida 1997-2001
ERIC Educational Resources Information Center
Johnson, Christopher E.; Dobalian, Aram; Burkhard, Janet; Hedgecock, Deborah K.; Harman, Jeffrey
2004-01-01
Purpose: We explore how nursing home characteristics affect the number of lawsuits filed against the facilities in Florida during the period from 1997 to 2001. Design and Methods: We examined data from 478 nursing homes in 30 Florida counties from 1997 to 2001. We obtained the data from Westlaw's Adverse Filings: Lawsuits database, the Online…
Perkins, William J; Davis, Dudley H; Huntoon, Marc A; Horlocker, Terese T
2003-06-01
A retained ferromagnetic catheter used for epidurolysis obscured diagnostic magnetic resonance imaging of the lumbar spine. The implications of this are discussed in light of other reports of retained catheter fragments obtained from the Food and Drug Administration Manufacturer and Facility Device Experience Database (http://www.fda.gov/cdrh/maude.html).