Motivational Antecedents of Preventive Proactivity in Late Life: Linking Future Orientation and Exercise1

PubMed Central

Kahana, Eva; Kahana, Boaz; Zhang, Jianping

2007-01-01

Future orientation is considered as a motivational antecedent of late-life proactivity. In a panel study of 453 old-old adults, we linked future orientation to exercise, a key component of late-life proactivity. Findings based on hierarchical linear modeling reveal that future orientation at baseline predicts changes in exercise during the subsequent four years. Whereas exercise behavior generally declined over time, future orientation and female gender were associated with smaller decline. These results suggest that future-oriented thinking has a lasting impact on health promotion behavior. Future orientation thus represents a dispositional antecedent of preventive proactivity as proposed in our successful aging model. PMID:18080009

Late pregnancy is vulnerable period for exposure to BPA.

PubMed

Ohtani, Naoko; Suda, Koshi; Tsuji, Erika; Tanemura, Kentaro; Yokota, Hiroshi; Inoue, Hiroki; Iwano, Hidetomo

2018-03-30

Bisphenol A (BPA) is among the better-known endocrine disruptors. BPA is used in various food-contacting materials and is easily eluted into food; as a result, we are exposed to BPA on a daily basis. In adults, BPA is metabolized and eliminated rapidly from the body. However, numerous reports suggest that fetuses and young children are susceptible to BPA. One of the concerning adverse effects of BPA is disruption of behavior, especially anxiety-like behavior. In order to study the mechanism of influences on offspring, it is important to clarify the most vulnerable gestation period. We hypothesized that offspring in late pregnancy would be more susceptible to BPA, because late pregnancy is a critical time for functional brain development. In this study, C57BL/6 mouse fetuses were exposed prenatally by oral dosing of pregnant dams, once daily from gestational day 5.5 to 12.5 (early pregnancy) or 11.5 to 18.5 (late pregnancy), with BPA (0 or 10 mg/kg body weight). Following birth and weaning, the resulting pups were tested using an elevated plus maze at postnatal week 10. The behavior of the offspring was altered by prenatal BPA exposure during late pregnancy but not during early pregnancy. These results indicated that offspring are more vulnerable to exposure to BPA in late pregnancy.

Pubertal changes in emotional information processing: pupillary, behavioral, and subjective evidence during emotional word identification.

PubMed

Silk, Jennifer S; Siegle, Greg J; Whalen, Diana J; Ostapenko, Laura J; Ladouceur, Cecile D; Dahl, Ronald E

2009-01-01

This study investigated pupillary and behavioral responses to an emotional word valence identification paradigm among 32 pre-/early pubertal and 34 mid-/late pubertal typically developing children and adolescents. Participants were asked to identify the valence of positive, negative, and neutral words while pupil dilation was assessed using an eyetracker. Mid-/late pubertal children showed greater peak pupillary reactivity to words presented during the emotional word identification task than pre-/early pubertal children, regardless of word valence. Mid-/late pubertal children also showed smaller sustained pupil dilation than pre-/early pubertal children after the word was no longer on screen. These findings were replicated controlling for participants' age. In addition, mid-/late pubertal children had faster reaction times to all words, and rated themselves as more emotional during their laboratory visit compared to pre-/early pubertal children. Greater recall of emotional words following the task was associated with mid-/late pubertal status, and greater recall of emotional words was also associated with higher peak pupil dilation. These results provide physiological, behavioral, and subjective evidence consistent with a model of puberty-specific changes in neurobehavioral systems underpinning emotional reactivity.

Pubertal Changes in Emotional Information Processing: Pupillary, Behavioral, and Subjective Evidence during Emotional Word Identification

PubMed Central

Silk, Jennifer S.; Siegle, Greg J.; Whalen, Diana J.; Ostapenko, Laura J.; Ladouceur, Cecile D.; Dahl, Ronald E.

2008-01-01

This study investigated pupillary and behavioral responses to an emotional word valence identification paradigm among 32 pre/early and 34 mid/late pubertal typically developing children and adolescents. Participants were asked to identify the valence of positive, negative, and neutral words while pupil dilation was assessed using an eye-tracker. Mid-to-late pubertal children showed greater peak pupillary reactivity to words presented during the emotional word identification task than pre-to-early pubertal children, regardless of word valence. Mid-to-late pubertal children also showed smaller sustained pupil dilation than pre-to-early pubertal children after the word was no longer on screen. These findings were replicated controlling for participants’ age. Additionally, mid-to-late pubertal children had faster reaction times to all words, and rated themselves as more emotional during their laboratory visit compared to pre-to-early pubertal children. Greater recall of emotional words following the task was associated with mid-to-late pubertal status, and greater recall of emotional words was also associated with higher peak pupil dilation. These results provide physiological, behavioral, and subjective evidence consistent with a model of puberty-specific changes in neurobehavioral systems underpinning emotional reactivity. PMID:19144220

Comparing Growth Trajectories of Risk Behaviors from Late Adolescence through Young Adulthood: An Accelerated Design

ERIC Educational Resources Information Center

Brodbeck, Jeannette; Bachmann, Monica S.; Croudace, Tim J.; Brown, Anna

2013-01-01

Risk behaviors such as substance use or deviance are often limited to the early stages of the life course. Whereas the onset of risk behavior is well studied, less is currently known about the decline and timing of cessation of risk behaviors of different domains during young adulthood. Prevalence and longitudinal developmental patterning of…

Therapist adherence is associated with outcome in cognitive-behavioral therapy for bulimia nervosa.

PubMed

Folke, Sofie; Daniel, Sarah I F; Gondan, Matthias; Lunn, Susanne; Tækker, Louise; Poulsen, Stig

2017-06-01

Studies of therapist adherence in relation to treatment outcome have produced mixed results. The aim of the present study was to investigate change in therapist adherence to cognitive-behavioral therapy (CBT) for bulimia nervosa over time, and to investigate the relationship between adherence and client outcome in early, middle, and late phases of treatment. Thirty-six clients received the focused form of "enhanced" CBT (CBT-E) for bulimia nervosa. Trained observers rated audiotapes of 92 full-length therapy sessions from early (Session 3), middle (Session 11), and late phases (Session 20) of treatment using the Cognitive-Behavioral Therapy Treatment Protocol Adherence Scale. Change in adherence across the 3 treatment phases was examined using multilevel analysis. The relationship between early, middle, and late adherence levels and end-of-treatment binging frequency was examined using multilevel Poisson regression analysis. Adherence decreased significantly over the course of treatment. Higher levels of therapist adherence in early and middle phases of treatment were associated with reduced binging frequency, whereas higher levels of adherence measured late in treatment was not. Results indicate that therapists' adherence to the CBT-E treatment protocol decreases over time and that high levels of protocol adherence in early and middle phases of treatment are more important for positive client outcomes than high levels of adherence in the end of treatment. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Endosomal Interactions during Root Hair Growth

PubMed Central

von Wangenheim, Daniel; Rosero, Amparo; Komis, George; Šamajová, Olga; Ovečka, Miroslav; Voigt, Boris; Šamaj, Jozef

2016-01-01

The dynamic localization of endosomal compartments labeled with targeted fluorescent protein tags is routinely followed by time lapse fluorescence microscopy approaches and single particle tracking algorithms. In this way trajectories of individual endosomes can be mapped and linked to physiological processes as cell growth. However, other aspects of dynamic behavior including endosomal interactions are difficult to follow in this manner. Therefore, we characterized the localization and dynamic properties of early and late endosomes throughout the entire course of root hair formation by means of spinning disc time lapse imaging and post-acquisition automated multitracking and quantitative analysis. Our results show differential motile behavior of early and late endosomes and interactions of late endosomes that may be specified to particular root hair domains. Detailed data analysis revealed a particular transient interaction between late endosomes—termed herein as dancing-endosomes—which is not concluding to vesicular fusion. Endosomes preferentially located in the root hair tip interacted as dancing-endosomes and traveled short distances during this interaction. Finally, sizes of early and late endosomes were addressed by means of super-resolution structured illumination microscopy (SIM) to corroborate measurements on the spinning disc. This is a first study providing quantitative microscopic data on dynamic spatio-temporal interactions of endosomes during root hair tip growth. PMID:26858728

Endosomal Interactions during Root Hair Growth.

PubMed

von Wangenheim, Daniel; Rosero, Amparo; Komis, George; Šamajová, Olga; Ovečka, Miroslav; Voigt, Boris; Šamaj, Jozef

2015-01-01

The dynamic localization of endosomal compartments labeled with targeted fluorescent protein tags is routinely followed by time lapse fluorescence microscopy approaches and single particle tracking algorithms. In this way trajectories of individual endosomes can be mapped and linked to physiological processes as cell growth. However, other aspects of dynamic behavior including endosomal interactions are difficult to follow in this manner. Therefore, we characterized the localization and dynamic properties of early and late endosomes throughout the entire course of root hair formation by means of spinning disc time lapse imaging and post-acquisition automated multitracking and quantitative analysis. Our results show differential motile behavior of early and late endosomes and interactions of late endosomes that may be specified to particular root hair domains. Detailed data analysis revealed a particular transient interaction between late endosomes-termed herein as dancing-endosomes-which is not concluding to vesicular fusion. Endosomes preferentially located in the root hair tip interacted as dancing-endosomes and traveled short distances during this interaction. Finally, sizes of early and late endosomes were addressed by means of super-resolution structured illumination microscopy (SIM) to corroborate measurements on the spinning disc. This is a first study providing quantitative microscopic data on dynamic spatio-temporal interactions of endosomes during root hair tip growth.

Developmental pathways from maltreatment to risk behavior: Sexual behavior as a catalyst.

PubMed

Negriff, Sonya

2018-05-01

Although delinquency, substance use, and sexual activity are established to be highly intercorrelated, the extant research provides minimal evidence in support of one particular sequence of risk behavior or on the cascade effects from maltreatment. The present study tested a longitudinal model incorporating maltreatment, deviant peers, sexual behavior, delinquency, and substance use to elucidate the sequential pathway(s) from maltreatment to each specific risk behavior throughout adolescence. Data came from a longitudinal study on the effects of maltreatment on adolescent development (N = 454) with four study assessments from early (Time 1 M age = 10.98) to late adolescence (Time 4 M age = 18.22). Results from the cross-lagged model showed a sequence from maltreatment to sexual behavior (Time 1), to delinquency (Time 2), to sexual behavior (Time 3), to substance use and delinquency (Time 4). These findings support sexual behavior as the initial risk behavior that is the catalyst for engagement in more advanced risk behaviors across adolescence.

Early, middle, or late administration of zoledronate alleviates spontaneous nociceptive behavior and restores functional outcomes in a mouse model of CFA-induced arthritis.

PubMed

Morado-Urbina, Carlos Eduardo; Alvarado-Vázquez, Perla Abigail; Montiel-Ruiz, Rosa Mariana; Acosta-González, Rosa Issel; Castañeda-Corral, Gabriela; Jiménez-Andrade, Juan Miguel

2014-11-01

This study was performed to evaluate whether early, middle, or late treatment of zoledronate, an approved bisphosphonate that blocks bone resorption, can reduce nociceptive behaviors in a mouse arthritis model. Arthritis was produced by repeated intra-articular knee injections of complete Freund's adjuvant (CFA). A dose-response curve with zoledronate (3, 30, 100, and 300 μg/kg, i.p., day 4 to day 25, twice weekly for 3 weeks) was performed, and the most effective dose of zoledronate (100 μg/kg, i.p.) was initially administered at different times of disease progression: day 4 (early), day 15 (middle), or day 21 (late) and continued until day 25 after the first CFA injection. Flinching of the injected extremity (spontaneous nociceptive behavior), vertical rearings and horizontal activity (functional outcomes), and knee edema were assessed. Zoledronate improved both functional outcomes and reduced flinching behavior. At day 25, the effect of zoledronate on flinching behavior and vertical rearings was greater in magnitude when it was given early or middle rather than late in the treatment regimen. Chronic zoledronate did not reduce knee edema in CFA-injected mice nor functional outcomes in naïve mice by itself. These results suggest that zoledronate may have a positive effect on arthritis-induced nociception and functional disabilities. © 2014 Wiley Periodicals, Inc.

Effect of Time-Dependent Selective Serotonin Reuptake Inhibitor Antidepressants During Pregnancy on Behavioral, Emotional, and Social Development in Preschool-Aged Children.

PubMed

Lupattelli, Angela; Wood, Mollie; Ystrom, Eivind; Skurtveit, Svetlana; Handal, Marte; Nordeng, Hedvig

2018-03-01

To evaluate the effect of prenatal exposure to selective serotonin reuptake inhibitors (SSRIs) on children's behavioral, emotional, and social development by age 5 years, and over time since age 1.5 years. The prospective Norwegian Mother and Child Cohort Study was linked to the Medical Birth Registry of Norway. We included women who reported depressive/anxiety disorders before and/or during pregnancy. Children born to women who used SSRIs in early (weeks 0-16), mid- (weeks 17-28), or late (> week 29) pregnancy were compared to those who were unexposed. Children's internalizing and externalizing behaviors (Child Behavior Checklist) and temperament traits (Emotionality, Activity and Shyness Temperament Questionnaire) were measured at 1.5, 3, and 5 years. Mean scores were calculated and standardized. General linear marginal structural models were fitted to account for time-varying exposure and confounders, and censoring; 3-level growth-curve models were used. A total of 8,359 mother-child dyads were included, and 4,128 children had complete outcome data at age 5 years. Children exposed to SSRIs in late pregnancy had an increased risk of anxious/depressed behaviors by age 5 years compared with unexposed children (adjusted β = 0.50, 95% CI = 0.04, 0.96). Such risk was not evident for earlier timings of exposure. There was no evidence for a substantial prenatal SSRI effect on externalizing, social, and emotional problems. These findings suggest no substantial increased risk for externalizing, emotional, or social problems in preschool-aged children following prenatal SSRI exposure. Although the role of chance and potential unmeasured confounding cannot be ruled out, late-pregnancy SSRI exposure was associated with greater anxious/depressed behaviors in the offspring. Copyright © 2017 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.

Fundamental Flux Equations for Fracture-Matrix Interactions with Linear Diffusion

NASA Astrophysics Data System (ADS)

Oldenburg, C. M.; Zhou, Q.; Rutqvist, J.; Birkholzer, J. T.

2017-12-01

The conventional dual-continuum models are only applicable for late-time behavior of pressure propagation in fractured rock, while discrete-fracture-network models may explicitly deal with matrix blocks at high computational expense. To address these issues, we developed a unified-form diffusive flux equation for 1D isotropic (spheres, cylinders, slabs) and 2D/3D rectangular matrix blocks (squares, cubes, rectangles, and rectangular parallelepipeds) by partitioning the entire dimensionless-time domain (Zhou et al., 2017a, b). For each matrix block, this flux equation consists of the early-time solution up until a switch-over time after which the late-time solution is applied to create continuity from early to late time. The early-time solutions are based on three-term polynomial functions in terms of square root of dimensionless time, with the coefficients dependent on dimensionless area-to-volume ratio and aspect ratios for rectangular blocks. For the late-time solutions, one exponential term is needed for isotropic blocks, while a few additional exponential terms are needed for highly anisotropic blocks. The time-partitioning method was also used for calculating pressure/concentration/temperature distribution within a matrix block. The approximate solution contains an error-function solution for early times and an exponential solution for late times, with relative errors less than 0.003. These solutions form the kernel of multirate and multidimensional hydraulic, solute and thermal diffusion in fractured reservoirs.

Adverse Life Events and Psychopathology and Prosocial Behavior in Late Adolescence: Testing the Timing, Specificity, Accumulation, Gradient, and Moderation of Contextual Risk

ERIC Educational Resources Information Center

Flouri, Eirini; Kallis, Constantinos

2007-01-01

A study examines the role of contextual risk in psychopathology and prosocial behavior in adolescents. The results show that risk accumulation matters instead of specificity and that the number of adverse life events is nonmultiplicative with psychopathology.

Better late than never: information retrieval from black holes.

PubMed

Braunstein, Samuel L; Pirandola, Stefano; Życzkowski, Karol

2013-03-08

We show that, in order to preserve the equivalence principle until late times in unitarily evaporating black holes, the thermodynamic entropy of a black hole must be primarily entropy of entanglement across the event horizon. For such black holes, we show that the information entering a black hole becomes encoded in correlations within a tripartite quantum state, the quantum analogue of a one-time pad, and is only decoded into the outgoing radiation very late in the evaporation. This behavior generically describes the unitary evaporation of highly entangled black holes and requires no specially designed evolution. Our work suggests the existence of a matter-field sum rule for any fundamental theory.

Time Management for Educators.

ERIC Educational Resources Information Center

Burden, Paul R.

Time management principles can help teachers become more aware of ways in which time can be used to the greatest advantage. An exploration of personal time perspectives is a step toward establishing effective patterns of behavior. Productivity may be high in the morning and low in the late afternoon, for example, and organizing some activities to…

Effect of bulk Lorentz violation on anisotropic brane cosmologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heydari-Fard, Malihe, E-mail: heydarifard@qom.ac.ir

2012-04-01

The effect of Lorentz invariance violation in cosmology has attracted a considerable amount of attention. By using a dynamical vector field assumed to point in the bulk direction, with Lorentz invariance holding on the brane, we extend the notation of Lorentz violation in four dimensions Jacobson to a five-dimensional brane-world. We obtain the general solution of the field equations in an exact parametric form for Bianchi type I space-time, with perfect fluid as a matter source. We show that the brane universe evolves from an isotropic/anisotropic state to an isotropic de Sitter inflationary phase at late time. The early timemore » behavior of anisotropic brane universe is largely dependent on the Lorentz violating parameters β{sub i},i = 1,2,3 and the equation of state of the matter, while its late time behavior is independent of these parameters.« less

Behavior problems in late childhood: the roles of early maternal attachment and teacher-child relationship trajectories.

PubMed

O'Connor, Erin E; Collins, Brian A; Supplee, Lauren

2012-01-01

The purposes of the current study were: (1) to examine the roles of early maternal attachment relationships and teacher-child relationships during childhood for externalizing and internalizing behaviors in late childhood, and (2) to investigate teacher-child relationships, as well as externalizing and internalizing behaviors in early childhood as possible mechanisms linking early maternal attachment relationships to behavior problems in late childhood. Longitudinal data from the National Institute of Child Health and Human Development Early Child Care Research Network Study of Early Child Care and Youth Development (N = 1140 mothers and children) were used in this investigation. There were three main findings. First, insecure/other maternal attachment relationships in early childhood (i.e., 36 months) were associated with externalizing and internalizing behaviors in late childhood (Grade 5). Second, elevated levels of teacher-child conflict during childhood were associated with externalizing behaviors in late childhood whereas low levels of teacher-child closeness were associated with internalizing behaviors. Third, the effects of insecure/other attachment on externalizing and internalizing behaviors in late childhood were mediated through teacher-child relationships during childhood and early externalizing and internalizing behaviors. Implications for attachment theory are discussed.

Prepartum Lying Behavior of Holstein Dairy Cows Housed on Pasture through Parturition

PubMed Central

Rice, Christa A.; Eberhart, Nicole L.; Krawczel, Peter D.

2017-01-01

Simple Summary Dairy cows experience meaningful biological changes during gestation that impact cow comfort and alter behavior, particularly during late gestation and leading up to calving. The housing environment can also have a positive or negative effect on cow comfort. Pasture access allows cows the freedom of movement and an ability to express natural grazing and resting behaviors. After observing cows housed on pasture during the late gestation and calving periods, this study found that lying behaviors only differed on the day of calving and the day prior to calving. Additionally, the proportion of time spent lying per hour decreased in the hour prior to calving compared to 6 h prior to parturition. The altered lying behaviors and activity observed in the hours before calving may indicate a decrease in cow comfort experienced by the cow during parturition. However, discomfort is typical of parturition. These data suggest that cows were able to express natural behaviors associated with calving and pasture when provided an adequate environment for cows during the prepartum period. Abstract Utilizing pasture-based systems may increase cow comfort during late gestation and calving as it lacks the constraints of confinement housing. The objective of this study was to quantify lying behavior and activity of Holstein dairy cows housed on pasture during the 6 d before calving. Sixteen Holstein dairy cows were moved to pasture 3 weeks before their projected calving date. Data loggers were attached 14 d prior to projected calving date. Behavior was evaluated 6 d before calving for all cows (n = 16) and 6 h prior to calving for a subset of cows (n = 6) with known calving times. Data loggers recorded at 1-min intervals to determine lying time (h/d and %/h), lying bouts (n/d and n/h), lying bout duration (min/bout), and steps (n/d and n/h). A repeated measures analysis of variance with contrasts was performed to determine if lying behaviors and activity differed between baseline and day or hour of interest. Lying time was greater 6 d prior to calving compared to the day of and before calving. Cows had longer lying bouts 6 d prior to calving compared to day of calving. Cows spent less time lying in the hour before calving compared to 6 h prior to parturition. The lack of change in behavior and activity during the 7 d prior to calving may indicate that pasture provided an adequate environment for cows during the prepartum period but did not impact cow welfare in the hours leading up to calving. PMID:28420107

Longitudinal Follow-up of Adolescents with Late-Onset Antisocial Behavior: A Pathological yet Overlooked Group

ERIC Educational Resources Information Center

Marmorstein, Naomi R.; Iacono, William G.

2005-01-01

Objective: Antisocial behavior that begins in mid- to late adolescence does not fit into commonly accepted taxonomies of antisocial behavior, yet it clearly exists. This study examined how this course of antisocial behavior compares with persisting (beginning by early adolescence and continuing through late adolescence) and desisting (stopping by…

Interactions between Callous Unemotional Behaviors and Executive Function in Early Childhood Predict later Aggression and Lower Peer-liking in Late-childhood.

PubMed

Waller, Rebecca; Hyde, Luke W; Baskin-Sommers, Arielle R; Olson, Sheryl L

2017-04-01

Callous unemotional (CU) behaviors are linked to aggression, behavior problems, and difficulties in peer relationships in children and adolescents. However, few studies have examined whether early childhood CU behaviors predict aggression or peer-rejection during late-childhood or potential moderation of this relationship by executive function. The current study examined whether the interaction of CU behaviors and executive function in early childhood predicted different forms of aggression in late-childhood, including proactive, reactive, and relational aggression, as well as how much children were liked by their peers. Data from cross-informant reports and multiple observational tasks were collected from a high-risk sample (N = 240; female = 118) at ages 3 and 10 years old. Parent reports of CU behaviors at age 3 predicted teacher reports of reactive, proactive, and relational aggression, as well as lower peer-liking at age 10. Moderation analysis showed that specifically at high levels of CU behaviors and low levels of observed executive function, children were reported by teachers as showing greater reactive and proactive aggression, and were less-liked by peers. Findings demonstrate that early childhood CU behaviors and executive function have unique main and interactive effects on both later aggression and lower peer-liking even when taking into account stability in behavior problems over time. By elucidating how CU behaviors and deficits in executive function potentiate each other during early childhood, we can better characterize the emergence of severe and persistent behavior and interpersonal difficulties across development.

Personal Network Characteristics as Predictors of Change in Obesity Risk Behaviors in Early Adolescence.

PubMed

Marks, Jennifer; de la Haye, Kayla; Barnett, Lisa M; Allender, Steven

2018-05-17

The potential for peers to influence obesity risk behavior increases in adolescence, yet there are knowledge gaps of how behaviors are modified in response to peers over time. This study examined how personal friendship network characteristics were associated with obesity-related behaviors from late childhood to early adolescence. Two waves of friendship, physical activity, screen time, and dietary recall data were collected from 11- to 13-year-old students (99% retention) in Australia (n = 308) over a five- to eight-month period. Regression models identified friendship network characteristics that predicted later health behaviors which varied by gender and behavior type, such as the number of friends positively associated with physical activity intensity (males) and screen time (females). The need for considering context to influence behavior change is discussed. © 2018 Society for Research on Adolescence.

Level of Cognitive Performance as a Correlate and Predictor of Health Behaviors that Protect against Cognitive Decline in Late Life: The Path through Life Study

ERIC Educational Resources Information Center

Anstey, Kaarin J.; Low, Lee-Fay; Christensen, Helen; Sachdev, Perminder

2009-01-01

There is a lack of information on how cognitive ability relates to both health behaviors and change in health behaviors over time. This study examined verbal ability and processing speed as predictors of health behaviors in the PATH Through Life Study that includes cohorts aged in their 20s, 40s and 60s. Higher cognitive scores were associated…

Determinants and prevalence of late HIV testing in Tijuana, Mexico.

PubMed

Carrizosa, Claudia M; Blumberg, Elaine J; Hovell, Melbourne F; Martinez-Donate, Ana P; Garcia-Gonzalez, Gregorio; Lozada, Remedios; Kelley, Norma J; Hofstetter, C Richard; Sipan, Carol L

2010-05-01

Timely diagnosis of HIV is essential to improve survival rates and reduce transmission of the virus. Insufficient progress has been made in effecting earlier HIV diagnoses. The Mexican border city of Tijuana has one of the highest AIDS incidence and mortality rates in all of Mexico. This study examined the prevalence and potential correlates of late HIV testing in Tijuana, Mexico. Late testers were defined as participants who had at least one of: (1) an AIDS-defining illness within 1 year of first positive HIV test; (2) a date of AIDS diagnosis within 1 year of first positive HIV test; or (3) an initial CD4 cell count below 200 cells per microliter within 1 year of first positive HIV test. Medical charts of 670 HIV-positive patients from two HIV/AIDS public clinics in Tijuana were reviewed and abstracted; 362 of these patients were interviewed using a cross-sectional survey. Using multivariate logistic regression, we explored potential correlates of late HIV testing based on the Behavioral Ecological Model. From 342 participants for whom late testing could be determined, the prevalence of late testing was 43.2%. Multivariate logistic regression results (n = 275) revealed five significant correlates of late testing: "I preferred not to know I had HIV" (adjusted odds ratio [AOR] = 2.78, 1.46-5.31); clinic (AOR = 1.90, 1.06-3.41); exposure to peers engaging in high-risk sexual behavior (AOR = 1.14, 1.02-1.27); stigma regarding HIV-infected individuals (AOR = 0.65, 0.47-0.92); and stigma regarding HIV testing (AOR = 0.66, 0.45-0.97). These findings may inform the design of interventions to increase timely HIV testing and help reduce HIV transmission in the community at large.

Nonlinear effects in time-dependent transonic flows: An analysis of analog black hole stability

NASA Astrophysics Data System (ADS)

Michel, Florent; Parentani, Renaud

2015-05-01

We study solutions of the one-dimensional Gross-Pitaevskii equation to better understand dynamical instabilities occurring in flowing atomic condensates. Whereas transonic stationary flows can be fully described in simple terms, time-dependent flows exhibit a wide variety of behaviors. When the sound speed is crossed once, we observe that flows analogous to black holes obey something similar to the so-called no hair theorem since their late time profile is stationary and uniquely fixed by parameters entering the Hamiltonian and conserved quantities. For flows analogous to white holes, at late time one finds a macroscopic undulation in the supersonic side which has either a fixed amplitude or a widely varying one, signaling a quasiperiodic emission of solitons on the subsonic side. When considering flows which cross the sound speed twice, we observe various scenarios which can be understood from the above behaviors and from the hierarchy of the growth rates of the dynamical instabilities characterizing such flows.

Determinants of employee punctuality.

PubMed

Dishon-Berkovits, Miriam; Koslowsky, Meni

2002-12-01

Although researchers have studied employee lateness empirically (e.g., S. Adler & J. Golan, 1981; C. W. Clegg, 1983), few have attempted to describe the punctual employee. In the present study, results of a discriminant analysis on employees in Israel indicated that a personality characteristic, time urgency, a subcomponent of Type A behavioral pattern, distinguished between punctual and late employees. Organizational commitment and age of employee's youngest child also distinguished between the groups.

Constructing counterproductive behavior for supporting evironmental management system research

NASA Astrophysics Data System (ADS)

Tiarapuspa; Indyastuti, D. L.; Sari, W. R.

2018-01-01

This study aims to explore the definition of counterproductive behavior based on supervisors’ and sub ordinaries’ perceptions. Recently, environmental management system is a strategic tool to gain a competitive advantage. Human resource is the vital factor for successful environmental management system. Counterproductive behavior will destroy environmental management system. Unfortunately, the construct of counterproductive behavior is still debatable. Different culture show different dimensions and indicators of counterproductive behavior. The unclear construct results ambiguous empirical evidence. This study results that many items are included of counterproductive behavior, such as come late, impolite communication, playing gadget in working time, and the other negative behaviors.

Characterizing neurocognitive late effects in childhood leukemia survivors using a combination of neuropsychological and cognitive neuroscience measures.

PubMed

Van Der Plas, Ellen; Erdman, Lauren; Nieman, Brian J; Weksberg, Rosanna; Butcher, Darci T; O'connor, Deborah L; Aufreiter, Susanne; Hitzler, Johann; Guger, Sharon L; Schachar, Russell J; Ito, Shinya; Spiegler, Brenda J

2017-10-10

Knowledge about cognitive late effects in survivors of childhood acute lymphoblastic leukemia (ALL) is largely based on standardized neuropsychological measures and parent reports. To examine whether cognitive neuroscience paradigms provided additional insights into neurocognitive and behavioral late effects in ALL survivors, we assessed cognition and behavior using a selection of cognitive neuroscience tasks and standardized measures probing domains previously demonstrated to be affected by chemotherapy. 130 ALL survivors and 158 control subjects, between 8 and 18 years old at time of testing, completed the n-back (working memory) and stop-signal (response inhibition) tasks. ALL survivors also completed standardized measures of intelligence (Wechsler Intelligence Scales [WISC-IV]), motor skills (Grooved Pegboard), math abilities (WIAT-III), and executive functions (Delis-Kaplan Executive Function System). Parents completed behavioral measures of executive functions (Behavior Rating Inventory of Executive Function [BRIEF]) and attention (Conners-3). ALL survivors exhibited deficiencies in working memory and response inhibition compared with controls. ALL survivors also exhibited deficits on WISC-IV working memory and processing speed, Grooved Pegboard, WIAT-III addition and subtraction fluency, and numerical operations, as well as DKEFS number-letter switching. Parent reports suggested more attention deficits (Conners-3) and behavioral difficulties (BRIEF) in ALL survivors compared with referenced norms. Low correspondence between standardized and experimental measures of working memory and response inhibition was noted. The use of cognitive neuroscience paradigms complements our understanding of the cognitive deficits evident after treatment of ALL. These measures could further delineate cognitive processes involved in neurocognitive late effects, providing opportunities to explore their underlying mechanisms.

Does Early Childhood Callous-Unemotional Behavior Uniquely Predict Behavior Problems or Callous-Unemotional Behavior in Late Childhood?

ERIC Educational Resources Information Center

Waller, Rebecca; Dishion, Thomas J.; Shaw, Daniel S.; Gardner, Frances; Wilson, Melvin N.; Hyde, Luke W.

2016-01-01

Callous-unemotional (CU) behavior has been linked to behavior problems in children and adolescents. However, few studies have examined whether CU behavior in "early childhood" predicts behavior problems or CU behavior in "late childhood". This study examined whether indicators of CU behavior at ages 2-4 predicted aggression,…

Intervention in the First Weeks of Life for Infants Born Late Preterm: A Case Series

PubMed Central

Dusing, Stacey C.; Lobo, Michele A.; Lee, Hui-Min; Galloway, James Cole

2013-01-01

Infants born late preterm (34–36 weeks of gestation) account for 350,000 US births per year, are at risk for developmental delays, and are rarely included in intervention studies. Purpose To describe a novel parent delivered movement intervention program for very young infants and outcomes following intervention and to evaluate the feasibility of using a comprehensive set of outcome measures. Summary of Key Points Two infants born late preterm received intervention from 0.5 to 2.0 months of adjusted age. Development, postural control, reaching, and object exploration assessments were completed at 3 time points. The intervention was well tolerated by the family. Improvements in developmental outcomes, postural control, and object exploration are presented. Statement of Conclusion Very early movement experience provided daily by parents may improve development. In combination, norm-referenced and behavioral measures appear sensitive to changes in infant behaviors. PMID:23542201

Increased anxiety-related behavior in male and female adult rats following early and late adolescent exposure to 3,4-methylenedioxymethamphetamine (MDMA).

PubMed

Kolyaduke, Olga V; Hughes, Robert N

2013-02-01

Subsequent behavioral effects in adulthood of daily exposure to MDMA during early or late adolescence were assessed in both male and female rats. From either postnatal day (PND) 35 (early adolescence) or PND45 (late adolescence), PVG/c rats of each sex were exposed via intraperitoneal injections to saline or 10mg/kg MDMA for 10 consecutive days. They were regularly weighed during treatment and again on PND90. At this age, their anxiety-related behavior was determined from frequencies of ambulation, rearing, grooming, defecation and occupancy of the center and corners of an open field, as well as entries into and time spent in the light compartment of a light-dark box. Spatial and working memories were assessed by preferences for a novel Y-maze arm, and by recognition of a novel object. MDMA-exposed rats gained less weight during treatment than saline controls but were heavier on PND90 depending on their sex or age when treated. As shown by decreased open-field ambulation (for males only) and increased defecation plus fewer entries into the light compartment of the light-dark box and entries into both arms of a Y maze, MDMA exposure increased adult anxiety-related behavior particularly for rats treated during late adolescence. There was no evidence of any effects on either spatial or working memory. Copyright © 2012 Elsevier Inc. All rights reserved.

Mechanical energy fluctuations in granular chains: the possibility of rogue fluctuations or waves.

PubMed

Han, Ding; Westley, Matthew; Sen, Surajit

2014-09-01

The existence of rogue or freak waves in the ocean has been known for some time. They have been reported in the context of optical lattices and the financial market. We ask whether such waves are generic to late time behavior in nonlinear systems. In that vein, we examine the dynamics of an alignment of spherical elastic beads held within fixed, rigid walls at zero precompression when they are subjected to sufficiently rich initial conditions. Here we define such waves generically as unusually large energy fluctuations that sustain for short periods of time. Our simulations suggest that such unusually large fluctuations ("hot spots") and occasional series of such fluctuations through space and time ("rogue fluctuations") are likely to exist in the late time dynamics of the granular chain system at zero dissipation. We show that while hot spots are common in late time evolution, rogue fluctuations are seen in purely nonlinear systems (i.e., no precompression) at late enough times. We next show that the number of such fluctuations grows exponentially with increasing nonlinearity whereas rogue fluctuations decrease superexponentially with increasing precompression. Dissipation-free granular alignment systems may be possible to realize as integrated circuits and hence our observations may potentially be testable in the laboratory.

Transient and late time attractor tachyon dark energy: Can we distinguish it from quintessence?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ali, Amna; Sami, M.; Sen, A. A.

2009-06-15

The string inspired tachyon field can serve as a candidate of dark energy. Its equation of state parameter w varies from 0 to -1. In the case of tachyon field potential V({phi}){yields}0 slower (faster) than 1/{phi}{sup 2} at infinity, dark energy (dark matter) is a late time attractor. We investigate the tachyon dark energy models under the assumption that w is close to -1. We find that all the models exhibit unique behavior around the present epoch which is exactly the same as that of the thawing quintessence.

The role of oxytocin in mothers' theory of mind and interactive behavior during the perinatal period.

PubMed

MacKinnon, Anna L; Gold, Ian; Feeley, Nancy; Hayton, Barbara; Carter, C Sue; Zelkowitz, Phyllis

2014-10-01

The present longitudinal study examined the relations between plasma oxytocin, theory of mind, and maternal interactive behavior during the perinatal period. A community sample of women was assessed at 12-14 weeks gestation, 32-34 weeks gestation, and 7-9 weeks postpartum. Oxytocin during late pregnancy was significantly positively correlated with a measure of theory of mind, and predicted theory of mind ability after controlling for parity, maternal education, prenatal psychosocial risk, and general anxiety, measured during the first trimester. Theory of mind was associated with less remote and less depressive maternal interactive behavior. Oxytocin, across all time points, was not directly related to maternal interactive behavior. However, there was a significant indirect effect of oxytocin during late pregnancy on depressive maternal behavior via theory of mind ability. These preliminary findings suggest that changes in the oxytocinergic system during the perinatal period may contribute to the awareness of social cues, which in turn plays a role in maternal interactive behavior. Copyright © 2014 Elsevier Ltd. All rights reserved.

Cosmology in time asymmetric extensions of general relativity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leon, Genly; Saridakis, Emmanuel N., E-mail: genly.leon@ucv.cl, E-mail: Emmanuel_Saridakis@baylor.edu

We investigate the cosmological behavior in a universe governed by time asymmetric extensions of general relativity, which is a novel modified gravity based on the addition of new, time-asymmetric, terms on the Hamiltonian framework, in a way that the algebra of constraints and local physics remain unchanged. Nevertheless, at cosmological scales these new terms can have significant effects that can alter the universe evolution, both at early and late times, and the freedom in the choice of the involved modification function makes the scenario able to produce a huge class of cosmological behaviors. For basic ansatzes of modification, we performmore » a detailed dynamical analysis, extracting the stable late-time solutions. Amongst others, we find that the universe can result in dark-energy dominated, accelerating solutions, even in the absence of an explicit cosmological constant, in which the dark energy can be quintessence-like, phantom-like, or behave as an effective cosmological constant. Moreover, it can result to matter-domination, or to a Big Rip, or experience the sequence from matter to dark energy domination. Additionally, in the case of closed curvature, the universe may experience a cosmological bounce or turnaround, or even cyclic behavior. Finally, these scenarios can easily satisfy the observational and phenomenological requirements. Hence, time asymmetric cosmology can be a good candidate for the description of the universe.« less

A finite difference model for free surface gravity drainage

DOE Office of Scientific and Technical Information (OSTI.GOV)

Couri, F.R.; Ramey, H.J. Jr.

1993-09-01

The unconfined gravity flow of liquid with a free surface into a well is a classical well test problem which has not been well understood by either hydrologists or petroleum engineers. Paradigms have led many authors to treat an incompressible flow as compressible flow to justify the delayed yield behavior of a time-drawdown test. A finite-difference model has been developed to simulate the free surface gravity flow of an unconfined single phase, infinitely large reservoir into a well. The model was verified with experimental results in sandbox models in the literature and with classical methods applied to observation wells inmore » the Groundwater literature. The simulator response was also compared with analytical Theis (1935) and Ramey et al. (1989) approaches for wellbore pressure at late producing times. The seepage face in the sandface and the delayed yield behavior were reproduced by the model considering a small liquid compressibility and incompressible porous medium. The potential buildup (recovery) simulated by the model evidenced a different- phenomenon from the drawdown, contrary to statements found in the Groundwater literature. Graphs of buildup potential vs time, buildup seepage face length vs time, and free surface head and sand bottom head radial profiles evidenced that the liquid refills the desaturating cone as a flat moving surface. The late time pseudo radial behavior was only approached after exaggerated long times.« less

Timing of Moderate Level Prenatal Alcohol Exposure Influences Gene Expression of Sensory Processing Behavior in Rhesus Monkeys

PubMed Central

Schneider, Mary L.; Moore, Colleen F.; Larson, Julie A.; Barr, Christina S.; DeJesus, Onofre T.; Roberts, Andrew D.

2009-01-01

Sensory processing disorder, characterized by over- or under-responsivity to non-noxious environmental stimuli, is a common but poorly understood disorder. We examined the role of prenatal alcohol exposure, serotonin transporter gene polymorphic region variation (rh5-HTTLPR), and striatal dopamine (DA) function on behavioral measures of sensory responsivity to repeated non-noxious sensory stimuli in macaque monkeys. Results indicated that early gestation alcohol exposure induced behavioral under-responsivity to environmental stimuli in monkeys carrying the short (s) rh5-HTTLPR allele compared to both early-exposed monkeys homozygous for the long (l) allele and monkeys from middle-to-late exposed pregnancies and controls, regardless of genotype. Moreover, prenatal timing of alcohol exposure altered the relationship between sensory scores and DA D2R availability. In early-exposed monkeys, a positive relationship was shown between sensory scores and DA D2R availability, with low or blunted DA function associated with under-responsive sensory function. The opposite pattern was found for the middle-to-late gestation alcohol-exposed group. These findings raise questions about how the timing of prenatal perturbation and genotype contributes to effects on neural processing and possibly alters neural connections. PMID:19936317

Factors affecting stability and change in risky driving from late adolescence to the late twenties.

PubMed

Vassallo, Suzanne; Lahausse, Julie; Edwards, Ben

2016-03-01

The risky driving tendencies of young drivers has been extensively researched, but much less is known about across-time patterns of risky driving behavior and the factors which influence these. This study identified factors associated with stable, increasing and decreasing risky driving trajectories among 751 Australian drivers participating in an ongoing longitudinal study. Five groups were formed on the basis of participants' patterns of risky driving from 19-20 to 27-28 years (i.e., stable low-risk, stable speeding, stable high-risk, increasing and decreasing). Very few participants exhibited a stable high-risk pattern. Characteristics that differentiated the different across-time groups were identified using Multinomial Logistic Regression. The most consistent correlates of risky driving patterns were antisocial behavior, binge drinking and relationship status. Sex, school completion, temperament, civic engagement, and antisocial peer friendships were also correlated with different across-time patterns. The implications of these findings for road safety are discussed. Crown Copyright © 2015. Published by Elsevier Ltd. All rights reserved.

Skin conductance level reactivity moderates the association between harsh parenting and growth in child externalizing behavior.

PubMed

Erath, Stephen A; El-Sheikh, Mona; Hinnant, J Benjamin; Cummings, E Mark

2011-05-01

Skin conductance level reactivity (SCLR) was examined as a moderator of the association between harsh parenting at age 8 years and growth in child externalizing behavior from age 8 to age 10 (N = 251). Mothers and fathers provided reports of harsh parenting and their children's externalizing behavior; children also provided reports of harsh parenting. SCLR was assessed in response to a socioemotional stress task and a problem-solving challenge task. Latent growth modeling revealed that boys with higher harsh parenting in conjunction with lower SCLR exhibited relatively high and stable levels of externalizing behavior during late childhood. Boys with higher harsh parenting and higher SCLR exhibited relatively low to moderate levels of externalizing behavior at age 8, but some results suggested that their externalizing behavior increased over time, approaching the same levels as boys with higher harsh parenting and lower SCLR by age 10. For the most part, girls and boys with lower harsh parenting were given relatively low and stable ratings of externalizing behavior throughout late childhood. Results are discussed from a developmental psychopathology perspective with reference to models of antisocial behavior in childhood. (c) 2011 APA, all rights reserved.

Skin Conductance Level Reactivity Moderates the Association Between Harsh Parenting and Growth in Child Externalizing Behavior

PubMed Central

Erath, Stephen A.; El-Sheikh, Mona; Hinnant, J. Benjamin; Cummings, E. Mark

2011-01-01

Skin conductance level reactivity (SCLR) was examined as a moderator of the association between harsh parenting at age 8 years and growth in child externalizing behavior from age 8 to age 10 (N = 251). Mothers and fathers provided reports of harsh parenting and their children’s externalizing behavior; children also provided reports of harsh parenting. SCLR was assessed in response to a socioemotional stress task and a problem-solving challenge task. Latent growth modeling revealed that boys with higher harsh parenting in conjunction with lower SCLR exhibited relatively high and stable levels of externalizing behavior during late childhood. Boys with higher harsh parenting and higher SCLR exhibited relatively low to moderate levels of externalizing behavior at age 8, but some results suggested that their externalizing behavior increased over time, approaching the same levels as boys with higher harsh parenting and lower SCLR by age 10. For the most part, girls and boys with lower harsh parenting were given relatively low and stable ratings of externalizing behavior throughout late childhood. Results are discussed from a developmental psychopathology perspective with reference to models of antisocial behavior in childhood. PMID:21142369

Limits of the potential flow approach to the single-mode Rayleigh-Taylor problem

NASA Astrophysics Data System (ADS)

Ramaprabhu, P.; Dimonte, Guy; Young, Yuan-Nan; Calder, A. C.; Fryxell, B.

2006-12-01

We report on the behavior of a single-wavelength Rayleigh-Taylor flow at late times. The calculations were performed in a long square duct (λ×λ×8λ) , using four different numerical simulations. In contradiction with potential flow theories that predict a constant terminal velocity, the single-wavelength Rayleigh-Taylor problem exhibits late-time acceleration. The onset of acceleration occurs as the bubble penetration depth exceeds the diameter of bubbles, and is observed for low and moderate density differences. Based on our simulations, we provide a phenomenological description of the observed acceleration, and ascribe this behavior to the formation of Kelvin-Helmholtz vortices on the bubble-spike interface that diminish the friction drag, while the associated induced flow propels the bubbles forward. For large density ratios, the formation of secondary instabilities is suppressed, and the bubbles remain terminal consistent with potential flow models.

Nesting behavior of Palila, as assessed from video recordings

USGS Publications Warehouse

Laut, M.E.; Banko, P.C.; Gray, E.M.

2003-01-01

We quantified nesting behavior of Palila (Loxiodes bailleui), an endangered Hawaiian honeycreeper, by recording at nests during three breeding seasons using a black-and-white video camera connected to a Videocassette recorder. A total of seven nests was observed. We measured the following factors for daylight hours: percentage of time the female was on the nest (attendance), length of attendance bouts by the female, length of nest recesses, and adult provisioning rates. Comparisons were made between three stages of the 40-day nesting cycle: incubation (day 1-day 16), early nestling stage (day 17-day 30 [i.e., nestlings ??? 14 days old]), and late nestling stage (day 31-day 40 [i.e., nestlings > 14 days old]). Of seven nests observed, four fledged at least one nestling and three failed. One of these failed nests was filmed being depredated by a feral cat (Felis catus). Female nest attendance was near 82% during the incubation stage and decreased to 21% as nestlings aged. We did not detect a difference in attendance bout length between stages of the nesting cycle. Mean length of nest recesses increased from 4.5 min during the incubation stage to over 45 min during the late nestling stage. Mean number of nest recesses per hour ranged from 1.6 to 2.0. Food was delivered to nestlings by adults an average of 1.8 times per hour for the early nestling stage and 1.5 times per hour during the late nestling stage and did not change over time. Characterization of parental behavior by video had similarities to but also key differences from findings taken from blind observations. Results from this study will facilitate greater understanding of Palila reproductive strategies.

Short sleep duration and irregular bedtime are associated with increased behavioral problems among Japanese preschool-age children.

PubMed

Komada, Yoko; Abe, Takashi; Okajima, Isa; Asaoka, Shoichi; Matsuura, Noriko; Usui, Akira; Shirakawa, Shuichiro; Inoue, Yuichi

2011-06-01

Sleep problems are known to be risk factors for subsequent emotional and behavioral difficulties in childhood and adolescence. To date, there has been no study investigating the relationships between sleep habits and behavioral problems in a large nonclinical sample of preschool age children. The aim of this study was to examine these relationships and factors associated with the sleep habits of preschool age (2 to 5 year old) children. Their mothers (n = 1,746) completed a multiple-choice questionnaire about the sleep habits and behavior problems of their children, as well as their own sleep habits and working hours at Tokyo metropolitan public nursery schools. The short sleep duration group showed significantly higher aggressive scores than the long sleep duration group among 2- to 3-year-old children, and the irregular bedtime group showed significantly higher aggressive and attention problem scores than the regular bedtime group among 4- to 5-year-old children. Univariate and multivariate logistic regression analyses revealed that children's late bedtime was associated with their mother's late waking-up time, and late schedule of both the mother's leaving and returning home. This study recognized an association between behavioral problems and poor sleep habits among preschool-age children. It is important for children to sleep regularly and adequately in order to decrease their behavior problems. In conclusion, appropriate management of children's sleep by their mothers is necessary for promoting sleep-related health of children.

Toward an understanding of late life suicidal behavior: the role of lifespan developmental theory.

PubMed

Fiske, Amy; O'Riley, Alisa A

2016-01-01

Suicidal behavior in late life differs in important ways from suicidal behavior that occurs earlier in the lifespan, suggesting the possibility of developmental differences in the etiology of suicidal behavior. This paper examines late life suicidal behavior within the context of lifespan developmental theory. This paper presents a conceptual framework for using lifespan developmental theory to better understand late life suicidal behavior. We argue that the motivational theory of lifespan development, which focuses on control, is particularly relevant to late life suicide. This theory posits that opportunities to exert control over important aspects of one's life diminish in late life as a result of declines in physical functioning and other factors, and that successful aging is associated with adaptive regulation of this developmental change. Although continued striving to meet goals is normative throughout the lifespan, most individuals also increase the use of compensatory strategies in old age or when faced with a decline in functioning. We propose that individuals who do not adapt to developmental changes by altering their strategies for exerting control will be at risk for suicidal behavior in late life. This paper reviews evidence that supports the importance of control with respect to suicidal outcomes in older adults, as well as findings regarding specific types of control strategies that may be related to suicide risk in older adults with health-related limitations. Although suicidal behavior is not a normal part of aging, the application of lifespan developmental theory may be useful in understanding and potentially preventing suicide among older adults.

Management of anxiety in late life.

PubMed

Flint, A J

1998-01-01

Epidemiologic data are used as a framework to discuss the pharmacologic and cognitive-behavioral management of anxiety disorders in late life. Generalized anxiety disorder (GAD) and phobias account for most cases of anxiety in late life. The high level of comorbidity between GAD and major depression, and the observation that the anxiety usually arises secondarily to the depression, suggests that antidepressant medication should be the primary pharmacologic treatment for many older people with GAD. Most individuals with late-onset agoraphobia do not have a history of panic attacks and the illness often starts after a traumatic event. Exposure therapy is the treatment of choice for agoraphobia without panic. It is uncommon for obsessive-compulsive disorder (OCD) and panic disorder to start for the first time in old age, but these disorders can persist from younger years into late life. Case reports and uncontrolled case series suggest that elderly people with OCD or panic disorder can benefit from pharmacologic and cognitive-behavioral treatments that are known to be effective in younger patients. However, it is not known whether the rate of response among elderly patients is adversely affected by the chronicity of these disorders. The prevalence and incidence of post-traumatic stress disorder in late life are not known. Uncontrolled data support the use of selective serotonin reuptake inhibitors in war veterans with chronic symptoms of post-traumatic stress disorder; other treatments for this condition await evaluation in the elderly.

The Continued Demise of Columbia Glacier: Insights On Dynamic Change

NASA Astrophysics Data System (ADS)

Enderlin, E. M.; Hamilton, G. S.; O'Neel, S.; Bartholomaus, T. C.

2016-12-01

Columbia Glacier, Alaska, has served as the archetype for the retreat phase of the tidewater glacier cycle for the past three decades. Since the mid-1980s, the terminus has retreated 16 kilometers and the two major tributaries have thinned by > 400 m. This retreat and thinning led to separation of the tributaries in the late 2000s. Since their separation, the tributaries have exhibited strikingly different dynamic behaviors over seasonal to inter-annual time scales as they continue to adjust to the long-term changes in glacier geometry. Here we use a combination of ground, airborne, and satellite remote sensing datasets to characterize the dynamic behavior of the Columbia Glacier system. We focus on the time period following tributary separation, when the observational record is most abundant, but also investigate longer-term changes in dynamics such as the reorganization of ice flow in the eastern tributary (Figure 1). From the mid 2000s through 2012, the tributaries thinned at comparable rates ( 25 m/yr) based on repeat DEM differencing. Their behavior diverged in 2012, when the eastern tributary appeared to stabilize but the western tributary continued its sustained thinning trend. Thinning resumed along the eastern tributary in late 2013, and was accompanied by modest terminus retreat and acceleration. In contrast, the rate of thinning dramatically increased along the western tributary as it began to rapidly retreat in late 2013. These changes coincided with the three-fold increase in flow speed and pronounced increase in iceberg discharge from the western tributary. Although variations in the timing and magnitude of the recent dynamic changes can be at least partially explained by differences in the geometries of the tributaries, the dynamic behavior of Columbia Glacier's major tributaries is unlikely to be totally independent of environmental perturbations (i.e., entirely driven by the long-term dynamic adjustment). To assess the influence of environmental perturbations on the dynamic behavior of the glacier, we compare weekly to multi-year changes in glacier dynamics constructed from our airborne and satellite remotely-sensed datasets to time series of frontal ablation (i.e., submarine melting and iceberg calving) and surface mass balance compiled from ground-based observations.

Adult brain and behavioral pathological markers of prenatal immune challenge during early/middle and late fetal development in mice.

PubMed

Meyer, Urs; Nyffeler, Myriel; Yee, Benjamin K; Knuesel, Irene; Feldon, Joram

2008-05-01

Maternal infection during pregnancy increases the risk for neurodevelopmental disorders such as schizophrenia and autism in the offspring. This association appears to be critically dependent on the precise prenatal timing. However, the extent to which distinct adult psychopathological and neuropathological traits may be sensitive to the precise times of prenatal immune activation remains to be further characterized. Here, we evaluated in a mouse model of prenatal immune challenge by the viral mimic, polyriboinosinic-polyribocytidilic acid (PolyIC), whether prenatal immune activation in early/middle and late gestation may influence the susceptibility to some of the critical cognitive, pharmacological, and neuroanatomical dysfunctions implicated in schizophrenia and autism. We revealed that PolyIC-induced prenatal immune challenge on gestation day (GD) 9 but not GD17 significantly impaired sensorimotor gating and reduced prefrontal dopamine D1 receptors in adulthood, whereas prenatal immune activation specifically in late gestation impaired working memory, potentiated the locomotor reaction to the NMDA-receptor antagonist dizocilpine, and reduced hippocampal NMDA-receptor subunit 1 expression. On the other hand, potentiation of the locomotor reaction to the dopamine-receptor agonist amphetamine and reduction in Reelin- and Parvalbumin-expressing prefrontal neurons emerged independently of the precise times of prenatal immune challenge. Our findings thus highlight that prenatal immune challenge during early/middle and late fetal development in mice leads to distinct brain and behavioral pathological symptom clusters in adulthood. Further examination and evaluation of in utero immune challenge at different times of gestation may provide important new insight into the neuroimmunological and neuropathological mechanisms underlying the segregation of different symptom clusters in heterogeneous neuropsychiatric disorders such as schizophrenia and autism.

Energy drink consumption, health complaints and late bedtime among young adolescents.

PubMed

Koivusilta, Leena; Kuoppamäki, Heini; Rimpelä, Arja

2016-04-01

Energy drinks contain large amounts of caffeine. Their effects on adolescent well-being are poorly known. We examined the relationship of energy drink consumption with health complaints and late bedtime among 13-year-olds. A classroom survey was conducted on all 7th graders in the Helsinki metropolitan region, Finland (73 % responded; n = 9446). Logistic regression analysis and structural equation modeling (SEM) were used. The prevalence of health complaints increased as energy drink consumption increased from non-consumers to several times/day. Late bedtime (≥11 PM) increased correspondingly. Those consuming energy drinks several times/day exhibited increased odds of experiencing daily health complaints compared with non-consumers: headache OR (adjusted) = 4.6 (2.8-7.7), sleeping problems OR = 3.6 (2.2-5.8), irritation OR = 4.1 (2.7-6.1), tiredness/fatigue OR = 3.7 (2.4-5.7), and late bedtime OR = 7.8 (5.7-10.9). In SEM, energy drink consumption had a direct effect on health complaints and late bedtime and an indirect effect on health complaints via late bedtime. Energy drinks, late bedtime, and health complaints form a behavior pattern that is worth considering in schools, home and clinical settings when adolescents complain about headaches, problems with sleeping and corresponding symptoms.

Long-term mass transfer and mixing-controlled reactions of a DNAPL plume from persistent residuals

NASA Astrophysics Data System (ADS)

Liu, Yuan; Illangasekare, Tissa H.; Kitanidis, Peter K.

2014-02-01

Understanding and being able to predict the long-term behavior of DNAPL (i.e., PCE and TCE) residuals after active remediation has ceased have become increasingly important as attention at many sites turns from aggressive remediation to monitored natural attenuation and long-term stewardship. However, plume behavior due to mass loading and reactions during these later phases is less studied as they involve large spatial and temporal scales. We apply both theoretical analysis and pore-scale simulations to investigate mass transfer from DNAPL residuals and subsequent reactions within the generated plume, and, in particular, to show the differences between early- and late-time behaviors of the plume. In the zone of entry of the DNAPL entrapment zone where the concentration boundary layer in the flowing groundwater has not fully developed, the pore-scale simulations confirm the past findings based on laboratory studies that the mass transfer increases as a power-law function of the Peclét number, and is enhanced due to reactions in the plume. Away from the entry zone and further down gradient, the long-term reactions are limited by the available additive and mixing in the porous medium, thereby behave considerably differently from the entry zone. For the reaction between the contaminant and an additive with intrinsic second-order bimolecular kinetics, the late-time reaction demonstrates a first-order decay macroscopically with respect to the mass of the limiting additive, not with respect to that of the contaminant. The late-time decay rate only depends on the intrinsic reaction rate and the solubility of the entrapped DNAPL. At the intermediate time, the additive decays exponentially with the square of time (t2), instead of time (t). Moreover, the intermediate decay rate also depends on the initial conditions, the spatial distribution of DNAPL residuals, and the effective dispersion coefficient.

Marriage Trajectories and Health Risk Behaviors Throughout Adulthood Among Urban African Americans

PubMed Central

Green, Kerry M.; Doherty, Elaine E.; Fothergill, Kate E.; Ensminger, Margaret E.

2015-01-01

Although previous studies have identified a protective effect of marriage on risky health behaviors, gaps remain in our understanding of how marriage improves health, particularly among African Americans. This study uses longitudinal data to take selection into account and examines whether marital trajectories that incorporate timing, stability, and duration of marriage affect health risk behaviors among a community cohort of urban African Americans followed for 35 years (N = 1,049). For both men and women, we find six marital trajectories. Men and women in consistently married trajectories are less likely to smoke, drink heavily (women only), and use illegal drugs than those in unmarried or previously married trajectories. Late marrying men do not fare worse in midlife than men in earlier marrying trajectories, but late marrying women show increased risk of midlife drug use. Results suggest policies supporting marriage may have an impact on health but only if stable unions are achieved. PMID:26136611

Peer influences on moral disengagement in late childhood and early adolescence.

PubMed

Caravita, Simona C S; Sijtsema, Jelle J; Rambaran, J Ashwin; Gini, Gianluca

2014-02-01

Moral disengagement processes are cognitive self-justification processes of transgressive actions that have been hypothesized to be learned and socialized within social contexts. The current study aimed at investigating socialization of moral disengagement by friends in two developmentally different age groups, namely late childhood (age: 9-10 years; n = 133, 42.9% girls) and early adolescence (age: 11-14 years; n = 236, 40.6% girls) over a 1-year period. Specifically, the current study examined whether similarity in moral disengagement between friends was the result of friends' influence or friend selection. Moreover, gender (42% girls), individual bullying behavior, and perceived popularity status were examined as potential moderators of socialization for moral disengagement within friendship networks. Self-report measures were used to assess moral disengagement, sociometric questions and a peer-nomination scale for friendship networks and bullying behavior, respectively. Longitudinal social network analysis (RSiena) was used to study change of moral disengagement in friendship networks during a 1-year interval. In early adolescence, friends were more likely to be similar to each other over time and this was explained only by influence processes and not by selection processes. Gender, bullying, and perceived popularity did not moderate the friends' influence on moral disengagement over time. Results indicate that self-justification processes change over time already in late childhood, but only in early adolescence this change is likely to be dependent upon peers' moral disengagement.

Maternal infection during late pregnancy increases anxiety- and depression-like behaviors with increasing age in male offspring.

PubMed

Enayati, Mohsen; Solati, Jalal; Hosseini, Mohammad-Hassan; Shahi, Hamid-Reza; Saki, Golshid; Salari, Ali-Akbar

2012-02-10

Scientific reports suggest that the exposure to long-term stressors throughout or during late gestation increase anxiety- and depression-like behaviors of offspring in their later life. Moreover, several studies concluded that increasing age correlates with increased anxiety behaviors in humans and rodents. In the present study, we assessed the effects of prenatally administration of equal lipopolysaccharide (LPS) doses in various points of late gestation (days 15, 16, and 17) period, on neuroendocrine and immunological responses of pregnant mice, and subsequent long-lasting consequences of anxiety and depression with increasing age in male offspring at postnatal days (PD) 40 and 80. Four hours after the LPS injection, levels of corticosterone (COR) and pro-inflammatory cytokines (PIC) in pregnant mice, as compared to the control dams, were increased significantly. Furthermore, maternal inflammation raised the levels of COR, anxiety- and depression-like behaviors with increasing age in male offspring in comparison with saline male offspring. These data support other studies demonstrating that maternal stress increases the levels of anxiety and depression in offspring. Additionally, our data confirm other findings indicating that increasing age correlates with increased anxiety or depression behaviors in humans and rodents. Findings of this study suggest that time course of an inflammation response or stressor application during various stages of gestation and ages of offspring are important factors for assessing neuropsychiatric disorders. Copyright © 2011 Elsevier Inc. All rights reserved.

Adult Behavior in Male Mice Exposed to E-Cigarette Nicotine Vapors during Late Prenatal and Early Postnatal Life

PubMed Central

Smith, Dani; Aherrera, Angela; Lopez, Armando; Neptune, Enid; Winickoff, Jonathan P.; Klein, Jonathan D.; Chen, Gang; Lazarus, Philip; Collaco, Joseph M.; McGrath-Morrow, Sharon A.

2015-01-01

Nicotine exposure has been associated with an increased likelihood of developing attention deficit hyperactivity disorder (ADHD) in offspring of mothers who smoked during pregnancy. The goal of this study was to determine if exposure to E-cigarette nicotine vapors during late prenatal and early postnatal life altered behavior in adult mice. Methods Timed-pregnant C57BL/6J mice were exposed to 2.4% nicotine in propylene glycol (PG) or 0% nicotine /PG once a day from gestational day 15 until delivery. After delivery, offspring and mothers were exposed to E-cigarette vapors for an additional 14 days from postnatal day 2 through 16. Following their last exposure serum cotinine levels were measured in female juvenile mice. Male mice underwent behavioral testing at 14 weeks of age to assess sensorimotor, affective, and cognitive functional domains. Results Adult male mice exposed to 2.4% nicotine/PG E-cigarette vapors had significantly more head dips in the zero maze test and higher levels of rearing activity in the open field test compared to 0% nicotine/PG exposed mice and untreated controls. In the water maze test after reversal training, the 2.4% nicotine/PG mice spent more than 25% of time in the new location whereas the other groups did not. Conclusion Adult male mice exhibited increased levels of activity in the zero maze and open field tests when exposed to E-cigarette vapor containing nicotine during late prenatal and early postnatal life. These findings indicate that nicotine exposure from E-cigarettes may cause persistent behavioral changes when exposure occurs during a period of rapid brain growth. PMID:26372012

The true quantum face of the "exponential" decay: Unstable systems in rest and in motion

NASA Astrophysics Data System (ADS)

Urbanowski, K.

2017-12-01

Results of theoretical studies and numerical calculations presented in the literature suggest that the survival probability P0(t) has the exponential form starting from times much smaller than the lifetime τ up to times t ⪢τ and that P0(t) exhibits inverse power-law behavior at the late time region for times longer than the so-called crossover time T ⪢ τ (The crossover time T is the time when the late time deviations of P0(t) from the exponential form begin to dominate). More detailed analysis of the problem shows that in fact the survival probability P0(t) can not take the pure exponential form at any time interval including times smaller than the lifetime τ or of the order of τ and it has has an oscillating form. We also study the survival probability of moving relativistic unstable particles with definite momentum . These studies show that late time deviations of the survival probability of these particles from the exponential-like form of the decay law, that is the transition times region between exponential-like and non-exponential form of the survival probability, should occur much earlier than it follows from the classical standard considerations.

Activation of GABA-A receptors during postnatal brain development increases anxiety- and depression-related behaviors in a time- and dose-dependent manner in adult mice.

PubMed

Salari, Ali-Akbar; Bakhtiari, Amir; Homberg, Judith R

2015-08-01

Disturbances of the gamma-amino butyric acid-ergic (GABAergic) system during postnatal development can have long-lasting consequences for later life behavior, like the individual's response to stress. However, it is unclear which postnatal windows of sensitivity to GABA-ergic modulations are associated with what later-life behavioral outcomes. Therefore, we sought to determine whether neonatal activation of the GABA-A receptor during two postnatal periods, an early window (postnatal day 3-5) and a late window (postnatal day 14-16), can affect anxiety- and depression-related behaviors in male mice in later life. To this end, mice were treated with either saline or muscimol (50, 100, 200, 300 and 500μg/kg) during the early and late postnatal periods. An additional group of mice was treated with the GABA-A receptor antagonist bicuculline+muscimol. When grown to adulthood male mice were exposed to behavioral tests to measure anxiety- and depression-related behaviors. Baseline and stress-induced corticosterone (CORT) levels were also measured. The results indicate that early postnatal and to a lesser extent later postnatal exposure to the GABA-A receptor agonist muscimol increased anxiety-like behavior and stress-induced CORT levels in adults. Moreover, the early postnatal treatment with muscimol increased depression-like behavior with increasing baseline CORT levels. The anxiogenic and depression-like later-life consequences could be antagonized by bicuculline. Our findings suggest that GABA-A receptor signaling during early-life can influence anxiety- and depression-related behaviors in a time- and dose-dependent manner in later life. Our findings help to increase insight in the developmental mechanisms contributing to stress-related disorders. Copyright © 2015 Elsevier B.V. and ECNP. All rights reserved.

Finding myself: a theory on the maturation of spirituality and its influence on behavior during late adolescence.

PubMed

Mason, Deanna M

2014-01-01

This study employed a grounded theory research design to develop a theoretical model focused on the maturation of spirituality and its influence on behavior during late adolescence. Quantitative research studies have linked spirituality with decreased health-risk behaviors and increased health-promotion behaviors during late adolescence. Qualitative, theoretical data is proposed to discover the underlying reasons this relationship exists and increase the ability to apply this knowledge to practice. Twenty-one adolescents, age 16-21 years, were e-mail interviewed and transcripts analyzed using a conceptual lens of Blumer's symbolic interactionism. From this analysis, a theoretical model emerged with the core concept, finding myself that represents 5 core process concepts. Implications of this study illustrate that late adolescents are aware of their personal spiritual maturation as well as its influence on behavior. In addition, a distinction between the generic concept of spirituality, personal spirituality, and religion emerged.

Comparisons of spawning areas and times for two runs of chinook salmon (Oncorhynchus tshawytscha) in the Kenai River, Alaska

USGS Publications Warehouse

Burger, C.V.; Wilmot, R.L.; Wangaard, D.B.

1985-01-01

From 1979 to 1982,188 chinook salmon (Oncorhynchus tshawytscha) were tagged with radio transmitters to locate spawning areas in the glacial Kenai River, southcentral Alaska. Results confirmed that an early run entered the river in May and June and spawned in tributaries, and a late run entered the river from late June through August and spawned in the main stem. Spawning peaked during August in tributaries influenced by lakes, but during July in other tributaries. Lakes may have increased fall and winter temperatures of downstream waters, enabling successful reproduction for later spawning fish within these tributaries. This hypothesis assumes that hatching and emergence can be completed in a shorter time in lake-influenced waters. The time of upstream migration and spawning (mid- to late August) of the late run is unique among chinook stocks in Cook Inlet. This behavior may have developed only because two large lakes (Kenai and Skilak) directly influence the main-stem Kenai River. If run timing is genetically controlled, and if the various components of the two runs are isolated stocks that have adapted to predictable stream temperatures, there are implications for stock transplantation programs and for any activities of man that alter stream temperatures.

Spatial Attention and Temporal Expectation Under Timed Uncertainty Predictably Modulate Neuronal Responses in Monkey V1

PubMed Central

Sharma, Jitendra; Sugihara, Hiroki; Katz, Yarden; Schummers, James; Tenenbaum, Joshua; Sur, Mriganka

2015-01-01

The brain uses attention and expectation as flexible devices for optimizing behavioral responses associated with expected but unpredictably timed events. The neural bases of attention and expectation are thought to engage higher cognitive loci; however, their influence at the level of primary visual cortex (V1) remains unknown. Here, we asked whether single-neuron responses in monkey V1 were influenced by an attention task of unpredictable duration. Monkeys covertly attended to a spot that remained unchanged for a fixed period and then abruptly disappeared at variable times, prompting a lever release for reward. We show that monkeys responded progressively faster and performed better as the trial duration increased. Neural responses also followed monkey's task engagement—there was an early, but short duration, response facilitation, followed by a late but sustained increase during the time monkeys expected the attention spot to disappear. This late attentional modulation was significantly and negatively correlated with the reaction time and was well explained by a modified hazard function. Such bimodal, time-dependent changes were, however, absent in a task that did not require explicit attentional engagement. Thus, V1 neurons carry reliable signals of attention and temporal expectation that correlate with predictable influences on monkeys' behavioral responses. PMID:24836689

The use of a driving simulator to determine how time pressures impact driver aggressiveness.

PubMed

Fitzpatrick, Cole D; Samuel, Siby; Knodler, Michael A

2017-11-01

Speeding greatly attributes to traffic safety with approximately a third of fatal crashes in the United States being speeding-related. Previous research has identified being late as a primary cause of speeding. In this driving simulator study, a virtual drive was constructed to evaluate how time pressures, or hurried driving, affected driver speed choice and driver behavior. In particular, acceleration profiles, gap acceptance, willingness to pass, and dilemma zone behavior were used, in addition to speed, as measures to evaluate whether being late increased risky and aggressive driving behaviors. Thirty-six drivers were recruited with an equal male/female split and a broad distribution of ages. Financial incentives and completion time goals calibrated from a control group were used to generate a Hurried and Very Hurried experimental group. As compared to the control group, Very Hurried drivers selected higher speeds, accelerated faster after red lights, accepted smaller gaps on left turns, were more likely to pass a slow vehicle, and were more likely to run a yellow light in a dilemma zone situation. These trends were statistically significant and were also evident with the Hurried group but a larger sample would be needed to show statistical significance. The findings from this study provide evidence that hurried drivers select higher speeds and exhibit riskier driving behaviors. These conclusive results have possible implications in areas such as transportation funding and commercial motor vehicle safety. Published by Elsevier Ltd.

ω-3 and folic acid act against depressive-like behavior and oxidative damage in the brain of rats subjected to early- or late-life stress.

PubMed

Réus, Gislaine Z; Maciel, Amanda L; Abelaira, Helena M; de Moura, Airam B; de Souza, Thays G; Dos Santos, Thais R; Darabas, Ana Caroline; Parzianello, Murilo; Matos, Danyela; Abatti, Mariane; Vieira, Ana Carolina; Fucillini, Vanessa; Michels, Monique; Dal-Pizzol, Felipe; Quevedo, João

2018-03-30

To investigate the antidepressant and antioxidant effects of omega-3, folic acid and n-acetylcysteine (NAC) in rats which were subjected to early or late life stress. Early stress was induced through maternal deprivation (MD), while late life stress was induced using the chronic mild stress (CMS) protocol. Young rats which were subjected to MD and the adult rats which were subjected to CMS were treated with omega-3 fatty acids (0.72 g/kg), NAC (20 mg/kg) or folic acid (50 mg/kg) once/day, for a period of 20 days. Then, the animals' immobility times were evaluated using the forced swimming test. Oxidative stress parameters were evaluated in the brain. Depressive-like behavior induced by CMS was prevented by NAC and folic acid, and depressive-like behavior induced by MD was prevented by NAC, folic acid and omega-3. NAC, folic acid and omega-3 were able to exert antioxidant effects in the brain of rats subjected to CMS or MD. These preventive treatments decreased the levels of protein carbonylation and lipid peroxidation, and also decreased the concentrations of nitrite/nitrate and reduced the activity of myeloperoxidase activity in the rat brain which was induced by CMS or MD. NAC, folic acid and omega-3 increased superoxide dismutase and catalase activities in the rat brain subjected to early or late life stress. NAC, omega-3 and folic acid may present interesting lines of treatment based on their antioxidant properties, which cause an inhibition of behavioral and brain changes that occur from stressful life events. Copyright © 2018 Elsevier Inc. All rights reserved.

Behavioral Differences Between Late Preweanling and Adult Female Sprague-Dawley Rat Exploration of Animate and Inanimate Stimuli and Food

PubMed Central

Smith, Kiersten S.; Morrell, Joan I.

2010-01-01

The late preweanling rat has potential as a preclinical model for disorders initially manifested in early childhood that are characterized by dysfunctional interactions with specific stimuli (e.g., obsessive-compulsive disorder and autism). No reports, however, of specific-stimulus exploration in the late preweanling rat are found in the literature. We examined the behavioral responses of normal late preweanling (PND 18-19) and adult rats when presented with exemplars of categorically-varied stimuli, including inanimate objects systematically varied in size and interactive properties, biological stimuli, and food. Preweanlings were faster to initiate specific stimulus exploration and were more interactive with most specific stimuli than adults; the magnitude of these preweanling-adult quantitative differences ranged from fairly small to very large depending upon the stimulus. In contrast, preweanlings were adult-like in their interaction with food and prey. Preweanling response to some stimuli, for example to live pups, was qualitatively different from that of adults; the preweanling behavioral repertoire was characterized by pup-seeking while the adult response was characterized by pup-avoidance. The specific stimulus interactions of preweanlings were less impacted than those of adults by the time of day of testing and placement of a stimulus in an anxiety-provoking location. The impact of novelty was stimulus dependent. The differences in interactions of preweanlings versus adults with specific stimuli suggests that CNS systems underlying these behavior patterns are at different stages of immaturity at PND 18 such that there may be an array of developmental trajectories for various categories of specific stimuli. These data provide a basis for the use of the preweanling as a preclinical model for understanding and medicating human disorders during development that are characterized by dysfunctional interactions with specific stimuli. PMID:21056059

Maternal depressive symptoms and physical activity in very low-income children

PubMed Central

Fernald, Lia C.H.; Jones-Smith, Jessica C.; Ozer, Emily J.; Neufeld, Lynnette M.; DiGirolamo, Ann M.

2009-01-01

Objective To test the contribution of maternal depression during late infancy to physical activity in children five years later. Method Children (n=168) from very low-income households in semi-urban Mexico were assessed as toddlers (15 mo, Time 1) and at pre-school age (4–6 y, Time 2). Child low activity level (<20 minutes of activity daily for <7 d/wk) at Time 2 was the primary outcome measure and maternal depressive symptoms (Center for Epidemiologic Studies – Depression Scale) by self report at Time 1 was the primary independent variable. Covariates tested included child age, sex, BMI percentile, television viewing and behavior (Behavior Problem Index sub-scales), current maternal depressive symptoms, age, BMI and physical activity level, and family socio-economic status; all covariates were assessed at Time 2 except for socio-economic status. Results At 4–6 years old, 27.5% of children were categorized with low activity level. Exposure to high maternal depressive symptoms at child age 15 months was associated with an increased risk of having a low activity level at age 4–6 years (OR, 2.38; 95% CI, 1.05–5.40); results were unchanged with the inclusion of current maternal depressive symptoms. High child TV-viewing was significantly associated with low activity level (OR, 5.44; 95% CI, 2.06–14.3), but did not change the effect of maternal depressive symptoms in early childhood. Tests of mediation revealed that current child internalizing behavior, but not externalizing behavior, significantly attenuated the association between early high maternal depressive symptoms and later childhood activity level. Conclusion Exposure to maternal depressive symptoms in late infancy is a risk factor for low activity level in later childhood and the association may be mediated by child internalizing factors. PMID:18714208

Time allocation by Greater White-fronted Geese: Influence of diet, energy reserves and predation

USGS Publications Warehouse

Ely, Craig R.

1992-01-01

I determined the amount of time Greater White-fronted Geese (Anser albifrons frontalis) allocated to various activities from September to May, 1980-1982 at their primary wintering areas in the Pacific Flyway of North America. The length of time spent on roosts during the day was positively correlated to day length. Geese at roost sites spent the majority of their time sleeping (24-46%), alert (17-40%), walking or swimming (6-24%), and in comfort behaviors (3-25%). The amount of time geese fed each day varied little from early autumn to late spring (4.5-4.9 hr), except during mid-winter when minimum temperatures were below freezing (3.9 hr), and immediately before migration in spring (6.3 hr). The proportion of time devoted to feeding and alert behavior, the two most dominant activities at field sites, varied significantly among seasons and locations. The amount of time geese were actively engaged in foraging each season was more dependent on feeding intensity than the amount of time spent at foraging sites (fields), and varied almost three-fold, from 1.8 hr during late winter to 5.1 hr during late spring. Geese fed in closer proximity to conspecifics, were more frequently disturbed, and spent less time feeding during the hunting season. Exploitation of high energy foods and catabolism of substantial energy reserves probably enabled geese to minimize foraging time during periods of harsh weather and high predation pressure. Seasonal variation in the proportion of time spent feeding corresponded closely to changes in body mass. Greater White-fronted Geese wintering in the Pacific Flyway spent substantially less time feeding than they do in Europe, as geese in California fed primarily on high energy cereal grains, while in Europe they subsist on green vegetation which has relatively less digestible energy than cereal grains.

The direction of effects between perceived parental behavioral control and psychological control and adolescents' self-reported GAD and SAD symptoms.

PubMed

Wijsbroek, Saskia A M; Hale, William W; Raaijmakers, Quinten A W; Meeus, Wim H J

2011-07-01

This study examined the direction of effects and age and sex differences between adolescents' perceptions of parental behavioral and psychological control and adolescents' self-reports of generalized anxiety disorder (GAD) and separation anxiety disorder (SAD) symptoms. The study focused on 1,313 Dutch adolescents (early-to-middle cohort n = 923, 70.3%; middle-to-late cohort n = 390, 29.7%) from the general population. A multi-group, structural equation model was employed to analyze the direction of the effects between behavioral control, psychological control and GAD and SAD symptoms for the adolescent cohorts. The current study demonstrated that a unidirectional child effect model of the adolescents' GAD and SAD symptoms predicting parental control best described the data. Additionally, adolescent GAD and SAD symptoms were stronger and more systematically related to psychological control than to behavioral control. With regard to age-sex differences, anxiety symptoms almost systematically predicted parental control over time for the early adolescent boys, whereas no significant differences were found between the late adolescent boys and girls.

[Analysis of parent-child sleeping and living habits related to later bedtimes in children].

PubMed

Shinkoda, Harumi; Suetsugu, Yoshiko; Asami, Eriko; Kato, Noriko; Kohyama, Jun; Uchimura, Naohisa; Chishaki, Akiko; Nishioka, Kazuo; Okubo, Ichiro; Matsumoto, Kazuya; Nanbu, Yumiko; Kaku, Tsunehisa

2012-01-01

To find the relationship between parents' sleeping and living behaviors and their children's sleeping habits, and to investigate factors specifically related to children staying up late in recent Japan. During regular health check-ups of children at three local health centers in the city A, we recruited the parents of one-and-half-year-old and three-year-old children to participate in the Child Sleep Cohort Project (ChiSCoP). Parents of 184 children who consented to participation were mailed three questionnaires by placement method. These are "sleeping diary for 10 days," "sleeping and lifetime rhythm survey," and "emotional behavior assessment scale (CBCL : Child Behavior Checklist 2rd/3rd edition)," of which valid data on 178 children were collected over two years and analyzed. Participants' demographic data, perceived and actual sleeping and living habits, and bedtime patterns were compared among the groups classified by bedtime of children. Bedtimes were classified as early (before 21 : 00), normal (21 : 00 to 21 : 59), and late (after 22 : 00). Using one-way analysis of variance with two (early vs. late) and three bedtime categories, significant differences were found among the three bedtime categories about childcare environmental factors (meal, daytime activity, TV, nap, and bath). So we performed logistic regression analysis with "late bedtime" as the dependent variable and scores of environmental factors (upper or lower than median values) as independent variables in a stepwise manner to eliminate collinear variables and to obtain adjusted odds ratios. 1) Among the 178 children, 96 and 82 were recruited during the physical check-up for one-and-half-year-old and three-years-old, respectively. There were 49, 72, and 57 children in the early, normal, and late bedtime groups, respectively, and no significant difference in attribute factors was found. 2) In children of the early bedtime group, proportions of those with "efforts to establish good life rhythm" (P < 0.0001), "efforts to cultivate sleeping habits" (P < 0.0001), and "keeping a regular bedtime" (P < 0.05) were significantly higher, as well as for children who had more than 105 minutes of "daytime nap" compared to children who had less (P < 0.05). 3) Children's bedtimes were significantly correlated with "mother's wake-up time on weekdays" (r = 0.33) and "mother's bedtime on weekdays" (r = 0.33). Children's wake-up times were also correlated with "mother's wake-up time on weekdays and weekends" (r = 0.49) and "mother's bedtime on weekdays" (r = 0.34), which indicates that children's wake-up times had relationship with mother's sleeping and life habits. 4) Later "wake-up time on weekends" (odds ratio = 4.9) and "regular bedtime hour" (odds ratio = 3.53) were found to be the determinant of late bedtimes of children. To encourage earlier bedtimes in children, it is important to take he mother's sleeping and living habits into account and to maintain a regular wake-up and bedtime schedule across weekdays and weekends.

Assessing the feasibility of harm reduction services for MSM: the late night breakfast buffet study

PubMed Central

Rose, Valerie J; Raymond, H Fisher; Kellogg, Timothy A; McFarland, Willi

2006-01-01

Background Despite the leveling off in new HIV infections among men who have sex with men (MSM) in San Francisco, new evidence suggests that many recent HIV infections are linked with the use of Methamphetamine (MA). Among anonymous HIV testers in San Francisco, HIV incidence among MA users was 6.3% compared to 2.1% among non-MA users. Of particular concern for prevention programs are frequent users and HIV positive men who use MA. These MSM pose a particular challenge to HIV prevention efforts due to the need to reach them during very late night hours. Methods The purpose of the Late Night Breakfast Buffet (LNBB) was to determine the feasibility and uptake of harm reduction services by a late night population of MSM. The "buffet" of services included: needle exchange, harm reduction information, oral HIV testing, and urine based sexually transmitted infection (STI) testing accompanied by counseling and consent procedures. The study had two components: harm reduction outreach and a behavioral survey. For 4 months during 2004, we provided van-based harm reduction services in three neighborhoods in San Francisco from 1 – 5 a.m. for anyone out late at night. We also administered a behavioral risk and service utilization survey among MSM. Results We exchanged 2000 needles in 233 needle exchange visits, distributed 4500 condoms/lubricants and provided 21 HIV tests and 12 STI tests. Fifty-five MSM enrolled in the study component. The study population of MSM was characterized by low levels of income and education whose ages ranged from 18 – 55. Seventy-eight percent used MA in the last 3 months; almost 25% used MA every day in the same time frame. Of the 65% who ever injected, 97% injected MA and 13% injected it several times a day. MA and alcohol were strong influences in the majority of unprotected sexual encounters among both HIV negative and HIV positive MSM. Conclusion We reached a disenfranchised population of MA-using MSM who are at risk for acquiring or transmitting HIV infection through multiple high risk behaviors, and we established the feasibility and acceptability of late night harm reduction for MSM and MSM who inject drugs. PMID:17018154

Light Goose Conservation Order effects on nontarget waterfowl behavior and energy expenditure

USGS Publications Warehouse

Dinges, Andrew J.; Webb, Elisabeth B.; Vrtiska, Mark P.

2016-01-01

When the Light Goose Conservation Order (LGCO) was established during 1999 in the Rainwater Basin of Nebraska, USA, LGCO activities were limited to 4 days/week and 16 public wetlands were closed to the LGCO to limit disturbance to nontarget waterfowl during this energetically important time period. However, the effects of LGCO activities on waterfowl behavior and energy expenditure are relatively unknown in this critical waterfowl staging area. To evaluate LGCO effects on target and nontarget species, we paired wetlands open and closed to LGCO and recorded waterfowl behavior and hunter encounters during springs 2011 and 2012. We constructed hourly energy expenditure models based on behavior data collected for mallards (Anas platyrhynchos) and northern pintails (A. acuta). In 2011, dabbling ducks (Anas spp.) spent more time feeding and less time resting in wetlands closed to hunting during early season when the majority of hunting encounters occurred; behaviors did not differ between hunt categories during late season when hunting activities subsided. However, in 2012, dabbling ducks spent more time feeding and less time resting in wetlands open to hunting during early and late seasons. We detected no differences in behaviors of lesser snow geese (Chen caerulescens) or greater white-fronted geese (Anser albifrons) between hunting categories in early season. Mallards had slightly greater energy expenditure on wetlands closed to hunting (  = 38.94 ± 0.31 kJ/bird/hr), compared with wetlands open to hunting (  = 37.87 ± 0.32 kJ/bird/hr); therefore, greater energy spent by mallards cannot be attributed to hunting disturbance. We also detected no differences in dabbling duck behavior or energy expenditure between days open or closed to hunting in the region. A refuge system of wetlands closed to LGCO activities in the Rainwater Basin may be an important management strategy in providing reduced disturbance for nontarget waterfowl species in some years. Published 2016. This article is a U.S. Government work and is in the public domain in the USA.

Interactions between callous unemotional behaviors and executive function in early childhood predict later socioemotional functioning

PubMed Central

Waller, Rebecca; Hyde, Luke W.; Baskin-Sommers, Arielle; Olson, Sheryl L.

2018-01-01

Callous unemotional (CU) behaviors are linked to aggression, behavior problems, and difficulties in peer relationships in children and adolescents. However, few studies have examined whether early childhood CU behaviors predict aggression or peer-rejection during late-childhood or potential moderation of this relationship by executive function. The current study examined whether the interaction of CU behaviors and executive function in early childhood predicted different forms of aggression in late-childhood, including proactive, reactive, and relational aggression, as well as how much children were liked by their peers. Data from cross-informant reports and multiple observational tasks were collected from a high-risk sample (N=240; female=118) at ages 3 and 10 years old. Parent reports of CU behaviors at age 3 predicted teacher reports of reactive, proactive, and relational aggression, as well as lower peer-liking at age 10. Moderation analysis showed that specifically at high levels of CU behaviors and low levels of observed executive function, children were reported by teachers as showing greater reactive and proactive aggression, and were less-liked by peers. Findings demonstrate that early childhood CU behaviors and executive function have unique main and interactive effects on both later aggression and lower peer-liking even when taking into account stability in behavior problems over time. By elucidating how CU behaviors and deficits in executive function potentiate each other during early childhood, we can better characterize the emergence of severe and persistent behavior and interpersonal difficulties across development. PMID:27418255

Evidence for a genetic etiology of early-onset delinquency.

PubMed

Taylor, J; Iacono, W G; McGue, M

2000-11-01

Age at onset of antisocial behavior discriminates persistent and transitory offenders. The authors proposed that early-onset delinquency has an underlying genetic influence that manifests in problems related to inhibition, whereas late-onset delinquency is more environmentally mediated. To test these notions, they selected 36 early starters, 86 late starters, and 25 nondelinquent controls from a large sample of 11-year-old twins and compared them on several measures related to inhibition and a peer group measure. As expected, early starters had more psychological, behavioral, and emotional problems related to inhibition than late starters and controls. A longitudinal analysis indicated an increase an antisocial behavior among peers of late starters shortly before their delinquency onset. Family history data and a twin analysis provided evidence of greater genetic influence on early-onset than late-onset delinquency.

Fractional Models Simulating Non-Fickian Behavior in Four-Stage Single-Well Push-Pull Tests

NASA Astrophysics Data System (ADS)

Chen, Kewei; Zhan, Hongbin; Yang, Qiang

2017-11-01

Four-stage single-well push-pull (SWPP) tracer tests, including injection, chasing, resting, and pumping, were conducted in a fractured aquifer at Newark basin. An anomalous transport phenomenon observed in the SWPP tests is the linear decline of breakthrough curves (BTCs) at late time with slope of -1.8 in log-log plots. A time-dependent fractional model is developed to interpret the anomalous transport behavior. This model considers a time-dependent power law memory function and a time-dependent fractional advection-dispersion operator. The fractional advection-dispersion equations (fADE) are solved in a radial coordinate system using the implicit Euler method. A semi-analytical solution of the first-order rate-limited mobile-immobile model (FORMIM) is derived for comparison. It is found that both the nonlocal transport in time and space can produce the long-tailed BTC. A smaller time-fractional or space-fractional index leads to a lower peak concentration and a larger late-time slope. The mass distribution of the fractional-in-space (FS) model exhibits power law decline at the leading plume edge. Early breakthrough during pumping is not observed because the mobile mass at the start of pumping is nonzero and more concentrated near the wellbore. The capacity ratio is an important factor that affects the peak concentration. A larger capacity ratio leads to greater peak concentration. A smaller time-fractional index in the injection, chasing, or resting stage will move the BTC downward and the slope of the late time BTC is determined by the space-fractional index over all stages and the time-fractional index in the pumping stage. The capability of the existing models to recover the BTC of the SWPP test is discussed and some guidelines for how to choose the appropriate model to interpret the SWPP test data are proposed.

Associations between Prosocial and Problem Behavior from Early to Late Adolescence.

PubMed

Padilla-Walker, Laura M; Memmott-Elison, Madison K; Coyne, Sarah M

2018-05-01

Though recent research has highlighted prosocial behavior as negatively associated with problem behavior during adolescence, we know little about how these variables might be associated longitudinally, whether there are bidirectional effects, and whether there might be different patterns of co-occurrence of behaviors for different individuals. Thus, the current study examined relations between prosocial and problem behaviors in three different ways in an attempt to better understand these associations. Participants included 500 adolescents recruited from a Northwestern state in the USA who took part in the study every year from age 12 to 18 (50% female, 67% European American). Growth curve analyses suggested that change in prosocial behavior was negatively associated with change in aggression and delinquency over time. A longitudinal panel model suggested that prosocial behavior and aggression were negatively associated bidirectionally, and that prosocial behavior was negatively associated with delinquency over time. Finally, mixture modeling conducted at ages 12, 15, and 18 revealed heterogeneity in the ways in which prosocial and problem behaviors co-occur. The discussion focuses on the complexity of interrelations between prosocial behavior and problem behavior across adolescence.

Executive functions and basic symptoms in adolescent antisocial behavior: a cross-sectional study on an Italian sample of late-onset offenders.

PubMed

Muscatello, Maria Rosaria A; Scimeca, Giuseppe; Pandolfo, Gianluca; Micò, Umberto; Romeo, Vincenzo M; Mallamace, Domenico; Mento, Carmela; Zoccali, Rocco; Bruno, Antonio

2014-04-01

Executive cognitive functions (ECFs) and other cognitive impairments, such as lower IQ and verbal deficits, have been associated with the pattern of antisocial and delinquent behavior starting in childhood (early-onset), but not with late-onset antisocial behavior. Beyond objective measures of ECF, basic symptoms are prodromal, subjectively experienced cognitive, perceptual, affective, and social disturbances, associated with a range of psychiatric disorders, mainly with psychosis. The goal of the present study was to examine ECF and basic symptoms in a sample of late-onset juvenile delinquents. Two-hundred nine male adolescents (aged 15-20 years) characterized by a pattern of late-onset delinquent behavior with no antecedents of Conduct Disorder, were consecutively recruited from the Social Services of the Department of Juvenile Justice of the city of Messina (Italy), and compared with nonantisocial controls matched for age, educational level, and socio-demographic features on measures for ECF dysfunction and basic symptoms. Significant differences between late-onset offenders (completers=147) and control group (n=150) were found on ECF and basic symptoms measures. Chi-square analysis showed that a significantly greater number of late-onset offending participants scored in the clinical range on several ECF measures. Executive cognitive impairment, even subtle and subclinical, along with subjective symptoms of cognitive dysfunction (basic symptom), may be contributing factor in the development and persistence of antisocial behaviors displayed by late-onset adolescent delinquents. The findings also suggest the need for additional research aimed to assess a broader range of cognitive abilities and specific vulnerability and risk factors for late-onset adolescent offenders. Copyright © 2014 Elsevier Inc. All rights reserved.

Risk Taking in Late Adolescence: Relations between Sociomoral Reasoning, Risk Stance, and Behavior

ERIC Educational Resources Information Center

Shaw, Leigh A.; Amsel, Eric; Schillo, Joshua

2011-01-01

This study explored relations among late adolescents' sociomoral reasoning about risk taking, risk stance, and behavior. One-hundred and thirty-two participants (18-20-year-olds) were surveyed about their own risk stance (Avoidant, Opportunistic, Curious, Risk Seeking) and behavior in three realms (Alcohol Use, Drug Use, Reckless Driving), and…

Development of exploratory behavior in late preterm infants.

PubMed

Soares, Daniele de Almeida; von Hofsten, Claes; Tudella, Eloisa

2012-12-01

Exploratory behaviors of 9 late preterm infants and 10 full-term infants were evaluated longitudinally at 5, 6 and 7 months of age. Eight exploratory behaviors were coded. The preterm infants mouthed the object less and had delayed gains in Waving compared to the full-term infants. Copyright © 2012 Elsevier Inc. All rights reserved.

Maternal Depression and Mother-Child Interaction Patterns: Association with Toddler Problems and Continuity of Effects to Late Childhood

ERIC Educational Resources Information Center

Leckman-Westin, Emily; Cohen, Patricia R.; Stueve, Ann

2009-01-01

Objective: Increased behavior problems have been reported in offspring of mothers with depression. In-home observations link maternal depressive symptoms (MDS) and mother-child interaction patterns with toddler behavior problems and examine their persistence into late childhood. Method: Maternal characteristics (N = 153) and behaviors of…

Neighborhood poverty and suicidal thoughts and attempts in late adolescence.

PubMed

Dupéré, V; Leventhal, T; Lacourse, E

2009-08-01

Suicide tends to concentrate in disadvantaged neighborhoods, and neighborhood disadvantage is associated with many important risk factors for youth suicide. However, no study has directly investigated the link between neighborhood poverty and youth suicidal behaviors, while controlling for pre-existing vulnerabilities. The objective of this study was to determine whether living in a poor neighborhood is associated with suicidal thoughts and attempts in late adolescence over and above background vulnerabilities, and whether this association can be explained by late-adolescence psychosocial risks: depression, social support, negative life events (NLEs), delinquent activities, substance abuse and exposure to suicide. The potential moderating role of neighborhood poverty was also examined. A subset of 2776 participants was selected from the Canadian National Longitudinal Survey of Children and Youth (NLSCY). Late-adolescence suicidal behaviors and risk factors were self-reported. The 2001 Canadian Census was used to characterize neighborhoods during early and middle adolescence. Late-childhood family and individual controls were assessed through parent-report. At the bivariate level, the odds of reporting suicidal thoughts were about twice as high in poor than non-poor neighborhoods, and the odds of attempting suicide were about four times higher. After controlling for background vulnerabilities, neighborhood poverty remained significantly associated with both suicidal thoughts and attempts. However, these associations were not explained by late-adolescence psychosocial risks. Rather, youth living in poor neighborhoods may be at greater risk through the amplification of other risk factors in disadvantaged neighborhoods. Potential explanations for the increased vulnerability of youth living in poor neighborhoods are discussed.

Investigation of the Stability of Human Freezing-Like Responses to Social Threat From Mid to Late Adolescence.

PubMed

Niermann, Hannah C M; Figner, Bernd; Tyborowska, Anna; Cillessen, Antonius H N; Roelofs, Karin

2018-01-01

Freezing behavior, a commonly observed defensive stress response, shows relatively high stability over time in animals. Given the relevance of freezing for stress-coping and human psychopathology, it is relevant to know whether freezing behavior is also stable in humans, particularly during adolescence, when most affective symptoms develop. In a prospective longitudinal study, we investigated freezing-like behavior in response to social threat in 75 adolescents at age 14, repeated 3 years later at age 17. We used a well-established method combining electrocardiography (ECG; heart rate) and posturography (body sway) in response to emotional picture-viewing of angry, happy, and neutral faces. We hypothesized that individual differences in freezing-like behavior in response to social threat-operationalized by contrasting angry vs. neutral faces-would be relatively stable over time. Our results indeed showed relative stability between ages 14 and 17 in individual differences in freezing-like behavior in heart rate ( r = 0.82), as well as in combined heart rate and body sway measures ( r = 0.65). These effects were not specific for the angry vs. neutral contrast; they were also visible in other emotion contrasts. Exploratory analysis in males and females separately showed stability in body sway specifically for angry vs. neutral faces only in females. Together, these results suggest moderate to strong stability in human freezing-like behavior in response to social threat from mid to late adolescence (with exception for the body sway measure in males). This relative stability was not specific for threat-induction and may reflect a general stability that is particularly strong for heart rate. The fact that this relative stability was found over a relatively long time range of 3 years is promising for studies aiming to use freezing-like behavior as a marker for internalizing symptoms in adolescent development.

Investigation of the Stability of Human Freezing-Like Responses to Social Threat From Mid to Late Adolescence

PubMed Central

Niermann, Hannah C. M.; Figner, Bernd; Tyborowska, Anna; Cillessen, Antonius H. N.; Roelofs, Karin

2018-01-01

Freezing behavior, a commonly observed defensive stress response, shows relatively high stability over time in animals. Given the relevance of freezing for stress-coping and human psychopathology, it is relevant to know whether freezing behavior is also stable in humans, particularly during adolescence, when most affective symptoms develop. In a prospective longitudinal study, we investigated freezing-like behavior in response to social threat in 75 adolescents at age 14, repeated 3 years later at age 17. We used a well-established method combining electrocardiography (ECG; heart rate) and posturography (body sway) in response to emotional picture-viewing of angry, happy, and neutral faces. We hypothesized that individual differences in freezing-like behavior in response to social threat—operationalized by contrasting angry vs. neutral faces—would be relatively stable over time. Our results indeed showed relative stability between ages 14 and 17 in individual differences in freezing-like behavior in heart rate (r = 0.82), as well as in combined heart rate and body sway measures (r = 0.65). These effects were not specific for the angry vs. neutral contrast; they were also visible in other emotion contrasts. Exploratory analysis in males and females separately showed stability in body sway specifically for angry vs. neutral faces only in females. Together, these results suggest moderate to strong stability in human freezing-like behavior in response to social threat from mid to late adolescence (with exception for the body sway measure in males). This relative stability was not specific for threat-induction and may reflect a general stability that is particularly strong for heart rate. The fact that this relative stability was found over a relatively long time range of 3 years is promising for studies aiming to use freezing-like behavior as a marker for internalizing symptoms in adolescent development. PMID:29867396

Smoking, Screen-Based Sedentary Behavior, and Diet Associated with Habitual Sleep Duration and Chronotype: Data from the UK Biobank.

PubMed

Patterson, Freda; Malone, Susan Kohl; Lozano, Alicia; Grandner, Michael A; Hanlon, Alexandra L

2016-10-01

Sleep duration has been implicated in the etiology of obesity but less is known about the association between sleep and other behavioral risk factors for cardiovascular disease. The aim of this study was to examine the associations among sleep duration, chronotype, and physical activity, screen-based sedentary behavior, tobacco use, and dietary intake. Regression models were used to examine sleep duration and chronotype as the predictors and cardiovascular risk factors as outcomes of interest in a cross-sectional sample of 439,933 adults enrolled in the UK Biobank project. Short sleepers were 45 % more likely to smoke tobacco than adequate sleepers (9.8 vs. 6.9 %, respectively). Late chronotypes were more than twice as likely to smoke tobacco than intermediate types (14.9 vs. 7.4 %, respectively). Long sleepers reported 0.61 more hours of television per day than adequate sleepers. Early chronotypes reported 0.20 fewer daily hours of computer use per day than intermediate chronotypes. Early chronotypes had 0.25 more servings of fruit and 0.13 more servings of vegetables per day than late chronotypes. Short and long sleep duration and late chronotype are associated with greater likelihood of cardiovascular risk behaviors. Further work is needed to determine whether these findings are maintained in the context of objective sleep and circadian estimates, and in more diverse samples. The extent to which promoting adequate sleep duration and earlier sleep timing improves heart health should also be examined prospectively.

Emotional and behavioral problems in late preterm and early term births: outcomes at child age 36 months.

PubMed

Stene-Larsen, Kim; Lang, Astri M; Landolt, Markus A; Latal, Beatrice; Vollrath, Margarete E

2016-12-01

Recent findings has shown that late preterm births (gestational weeks 34-36) and early term births (gestational weeks 37-38) is associated with an increased risk of several psychological and developmental morbidities. In this article we investigate whether late preterm and early term births is associated with an increased risk of emotional and behavioral problems at 36 months of age and whether there are gender differences in risk of these outcomes. Forty-three thousand, two hundred ninety-seven children and their mothers participating in the Norwegian Mother and Child Cohort Study (MoBa). One thousand, eight hundred fifty-three (4.3%) of the children in the sample were born late preterm and 7,835 (18.1%) were born early term. Information on gestational age and on prenatal and postnatal risk factors was retrieved from the Medical Birth Registry of Norway. Information on emotional and behavioral problems was assessed by standardized questionnaires (CBCL/ITSEA) filled out by the mothers. Gender-stratified logistic regression analyses were used to explore the association between late preterm / early term and emotional and behavioral problems at 36 months of age. We found a gender-specific increased risk of emotional problems in girls born late preterm (OR 1.47 95%CI 1.11-1.95) and in girls born early term (OR 1.21 95%CI 1.04-1.42). We did not find an increased risk of emotional problems in boys born late preterm (OR 1.09 95%CI 0.82-1.45) or early term (OR 0.93 95%CI 0.79-1.10). Behavioral problems were not increased in children born late preterm or early term. Girls born late preterm and early term show an increased risk of emotional problems at 36 months of age. This finding suggests that gender should be taken into account when evaluating children born at these gestational ages.

Temporal and environmental patterns of sedentary and active behaviors during adolescents' leisure time.

PubMed

Biddle, Stuart J H; Marshall, Simon J; Gorely, Trish; Cameron, Noel

2009-01-01

There is great interest in young people's overweight and obesity. Few data, however, describe when sedentary and physically active behaviors are likely to occur during the day or how these behaviors are related to location. The purpose of this study was to describe sedentary and active leisure-time behaviors of adolescents across the day and setting. Adolescents (male n = 579, female n = 967; aged 13-16 years) completed time-use diaries for three weekdays and one weekend day. At 15 min intervals, participants recorded what they were doing and where they were. TV viewing and sports/exercise peaked at different times in the day, although TV viewing was two to three times more likely to occur than sports/exercise. TV viewing was most likely to occur during the middle to late evening. The playing of computer games was low, particularly for girls. Weekend data showed TV viewing was the most reported activity throughout the day. For boys, "being in the garden" was highly predictive of engaging in sports/exercise, but this declined rapidly with age. Motorized travel to school was reported twice as often as active travel. Momentary assessments of behavior, in conjunction with contemporaneous reports of environmental factors, describe important patterns of leisure-time active and sedentary behaviors in youth.

Recognizing pedestrian's unsafe behaviors in far-infrared imagery at night

NASA Astrophysics Data System (ADS)

Lee, Eun Ju; Ko, Byoung Chul; Nam, Jae-Yeal

2016-05-01

Pedestrian behavior recognition is important work for early accident prevention in advanced driver assistance system (ADAS). In particular, because most pedestrian-vehicle crashes are occurred from late of night to early of dawn, our study focus on recognizing unsafe behavior of pedestrians using thermal image captured from moving vehicle at night. For recognizing unsafe behavior, this study uses convolutional neural network (CNN) which shows high quality of recognition performance. However, because traditional CNN requires the very expensive training time and memory, we design the light CNN consisted of two convolutional layers and two subsampling layers for real-time processing of vehicle applications. In addition, we combine light CNN with boosted random forest (Boosted RF) classifier so that the output of CNN is not fully connected with the classifier but randomly connected with Boosted random forest. We named this CNN as randomly connected CNN (RC-CNN). The proposed method was successfully applied to the pedestrian unsafe behavior (PUB) dataset captured from far-infrared camera at night and its behavior recognition accuracy is confirmed to be higher than that of some algorithms related to CNNs, with a shorter processing time.

Elasticity-Driven Backflow of Fluid-Driven Cracks

NASA Astrophysics Data System (ADS)

Lai, Ching-Yao; Dressaire, Emilie; Ramon, Guy; Huppert, Herbert; Stone, Howard A.

2016-11-01

Fluid-driven cracks are generated by the injection of pressurized fluid into an elastic medium. Once the injection pressure is released, the crack closes up due to elasticity and the fluid in the crack drains out of the crack through an outlet, which we refer to as backflow. We experimentally study the effects of crack size, elasticity of the matrix, and fluid viscosity on the backflow dynamics. During backflow, the volume of liquid remaining in the crack as a function of time exhibits a transition from a fast decay at early times to a power law behavior at late times. Our results at late times can be explained by scaling arguments balancing elastic and viscous stresses in the crack. This work may relate to the environmental issue of flowback in hydraulic fracturing. This work is supported by National Science Foundation via Grant CBET-1509347 and partially supported by Andlinger Center for Energy and the Environment at Princeton University.

The Late-time Afterglow of the Extremely Energetic Short Burst GRB 090510 Revisited

NASA Technical Reports Server (NTRS)

Guelbenzu, A. Nicuesa; Klose, S.; Kruehler, T.; Greiner, J.; Rossi, A.; Kann, D. A.; Olivares, F.; Rau, A.; Afonso, P. M. J.; Elliott, J.;

Spatial Attention and Temporal Expectation Under Timed Uncertainty Predictably Modulate Neuronal Responses in Monkey V1.

PubMed

Sharma, Jitendra; Sugihara, Hiroki; Katz, Yarden; Schummers, James; Tenenbaum, Joshua; Sur, Mriganka

2015-09-01

The brain uses attention and expectation as flexible devices for optimizing behavioral responses associated with expected but unpredictably timed events. The neural bases of attention and expectation are thought to engage higher cognitive loci; however, their influence at the level of primary visual cortex (V1) remains unknown. Here, we asked whether single-neuron responses in monkey V1 were influenced by an attention task of unpredictable duration. Monkeys covertly attended to a spot that remained unchanged for a fixed period and then abruptly disappeared at variable times, prompting a lever release for reward. We show that monkeys responded progressively faster and performed better as the trial duration increased. Neural responses also followed monkey's task engagement-there was an early, but short duration, response facilitation, followed by a late but sustained increase during the time monkeys expected the attention spot to disappear. This late attentional modulation was significantly and negatively correlated with the reaction time and was well explained by a modified hazard function. Such bimodal, time-dependent changes were, however, absent in a task that did not require explicit attentional engagement. Thus, V1 neurons carry reliable signals of attention and temporal expectation that correlate with predictable influences on monkeys' behavioral responses. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

A Temporal Correlation in Quiescent Gamma-Ray Burst Prompt Emission: Evidence for Prognitor Memory

NASA Astrophysics Data System (ADS)

Patton, Thomas L.; Giblin, Timothy; Hakkila, Jon E.

2018-06-01

In spite of the insight gained into the nature of the Gamma-Ray Bursts (GRB) from early and late-time X-Ray observations in the Swift era, GRB prompt emission continues to provide clues and new insight into the activity of the central engine. A comprehensive understanding of all emission components observed in GRBs, from the traditional prompt GRB emission to the long lived X-Ray and optical decay super- imposed with late-time flaring activity, currently remains allusive. Using data from the Swift Burst Alert Telescope (BAT), we've identified and measured durations observed in GRBs that exhibit multi-episodic prompt emission behavior. Duration analysis of the burst attributes revealed no significant correlations between emissions and quiet time durations. This variability allows us to extrapolate that the central engine is constantly active.

Information scrambling at an impurity quantum critical point

NASA Astrophysics Data System (ADS)

Dóra, Balázs; Werner, Miklós Antal; Moca, Cǎtǎlin Paşcu

2017-10-01

The two-channel Kondo impurity model realizes a local non-Fermi-liquid state with finite residual entropy. The competition between the two channels drives the system to an impurity quantum critical point. We show that the out-of-time-ordered (OTO) commutator for the impurity spin reveals markedly distinct behavior depending on the low-energy impurity state. For the one-channel Kondo model with Fermi-liquid ground state, the OTO commutator vanishes for late times, indicating the absence of the butterfly effect. For the two channel case, the impurity OTO commutator is completely temperature independent and saturates quickly to its upper bound 1/4, and the butterfly effect is maximally enhanced. These compare favorably to numerics on spin chain representation of the Kondo model. Our results imply that a large late time value of the OTO commutator does not necessarily diagnose quantum chaos.

Adult Behavior in Male Mice Exposed to E-Cigarette Nicotine Vapors during Late Prenatal and Early Postnatal Life.

PubMed

Smith, Dani; Aherrera, Angela; Lopez, Armando; Neptune, Enid; Winickoff, Jonathan P; Klein, Jonathan D; Chen, Gang; Lazarus, Philip; Collaco, Joseph M; McGrath-Morrow, Sharon A

2015-01-01

Timed-pregnant C57BL/6J mice were exposed to 2.4% nicotine in propylene glycol (PG) or 0% nicotine /PG once a day from gestational day 15 until delivery. After delivery, offspring and mothers were exposed to E-cigarette vapors for an additional 14 days from postnatal day 2 through 16. Following their last exposure serum cotinine levels were measured in female juvenile mice. Male mice underwent behavioral testing at 14 weeks of age to assess sensorimotor, affective, and cognitive functional domains. Adult male mice exposed to 2.4% nicotine/PG E-cigarette vapors had significantly more head dips in the zero maze test and higher levels of rearing activity in the open field test compared to 0% nicotine/PG exposed mice and untreated controls. In the water maze test after reversal training, the 2.4% nicotine/PG mice spent more than 25% of time in the new location whereas the other groups did not. Adult male mice exhibited increased levels of activity in the zero maze and open field tests when exposed to E-cigarette vapor containing nicotine during late prenatal and early postnatal life. These findings indicate that nicotine exposure from E-cigarettes may cause persistent behavioral changes when exposure occurs during a period of rapid brain growth.

Precocious Puberty in Adolescent Girls: A Biomarker of Later Psychosocial Adjustment Problems

ERIC Educational Resources Information Center

Tremblay, Line; Frigon, Jean-Yves

2005-01-01

We have investigated the hypothesis that stress condition will accelerate pubertal maturation in adolescent girls and that faster maturing girls will display more behavioral problems than their on-time or late-maturing peers during pubertal development. Longitudinal data were collected yearly from 1986 to 1997. Parents of 1039 French-speaking…

Time-Series Analysis of Therapeutic Process and Outcome: An Eating Disorder.

ERIC Educational Resources Information Center

Hannah, Gregory L.; Rave, Elizabeth J.

Much literature on eating disorders has been published since the late 1970's but authorities still do not agree on terminology or diagnostic criteria. Suggested therapies have included group therapy, individual and family therapy, medical procedures, incorporation of an anxiety model, behavior therapy, and feminist therapy. Therapists need to…

Survivors of childhood cancer in South Australia attending a late-effects clinic: a descriptive report of psychological, cognitive, and academic late-effects.

PubMed

Roberts, Rachel M; Robins, Tamara; Gannoni, Anne F; Tapp, Heather

2014-01-01

This study provides a description of psychological late effects among a heterogeneous cohort of pediatric cancer survivors (N = 70) attending the South Australian Late-effects Clinic. Survivors reported more problems on the Strengths and Difficulties Questionnaire and the Child Behavior Checklist compared to normative data but no differences in Sluggish Cognitive Tempo scores. Forty-six percent of the sample reported school difficulties, and 12% of the sample age older than 15 reported smoking. Late-effects clinics should continue to monitor psychological well-being and health behaviors. Further research is recommended to determine whether sluggish cognitive tempo is a useful concept for the assessment of survivors.

Transitions in Smoking Behavior During Emerging Adulthood: A Longitudinal Analysis of the Effect of Home Smoking Bans

PubMed Central

Stigler, Melissa H.; Erickson, Darin J.; Perry, Cheryl L.; Forster, Jean L.

2014-01-01

Objectives. We studied the effect of home smoking bans on transitions in smoking behavior during emerging adulthood. Methods. We used latent transition analysis to examine movement between stages of smoking from late adolescence (ages 16–18 years) to young adulthood (ages 18–20 years) and the effect of a home smoking ban on these transitions. We used data from the Minnesota Adolescent Community Cohort study collected in 2004 to 2006. Results. Overall, we identified 4 stages of smoking: (1) never smokers, (2) experimental smokers, (3) light smokers, and (4) daily smokers. Transition probabilities varied by stage. Young adults with a home ban during late adolescence were less likely to be smokers and less likely to progress to higher use later. Furthermore, the protective effect of a home smoking ban on the prevalence of smoking behavior was evident even in the presence of parental smoking. However, this effect was less clear on transitions over time. Conclusions. In addition to protecting family members from exposure to secondhand smoke, home smoking bans appear to have the additional benefit of reducing initiation and escalation of smoking behavior among young adults. PMID:24524528

Participation in an Intensive Longitudinal Study with Weekly Web Surveys Over 2.5 Years

PubMed Central

Barber, Jennifer; Kusunoki, Yasamin; Schulz, Paul

2016-01-01

Background Technological advances have made it easier for researchers to collect more frequent longitudinal data from survey respondents via personal computers, smartphones, and other mobile devices. Although technology has led to an increase in data-intensive longitudinal studies, little is known about attrition from such studies or the differences between respondents who complete frequently administered surveys in a timely manner, and respondents who do not. Objective We examined respondent characteristics and behaviors associated with continued and on-time participation in a population-based intensive longitudinal study, using weekly web-based survey interviews over an extended period. Methods We analyzed data from the Relationship Dynamics and Social Life study, an intensive longitudinal study that collected weekly web-based survey interviews for 2.5 years from 1003 18- and 19-year-olds to investigate factors shaping the dynamics of their sexual behavior, contraceptive use, and pregnancies. Results Ordinary least squares and logistic regression analyses showed background respondent characteristics measured at baseline were associated with the number of days respondents remained enrolled in the study, the number of interviews they completed, and the odds that they were late completing interviews. In addition, we found that changes in pregnancy-related behaviors reported in the weekly interviews were associated with late completion of interviews. Specifically, after controlling for sociodemographic, personality, contact information, and prior experience variables, we found that weekly reports such as starting to have sex (odds ratio [OR] 1.17, 95% CI 1.03-1.32, P=.01), getting a new partner (OR 1.76, 95% CI 1.53-2.03, P<.001), stopping the use of contraception (OR 1.28, 95% CI 1.10-1.49, P=.001), and having a new pregnancy (OR 5.57, 95% CI 4.26-7.29, P<.001) were significantly associated with late survey completion. However, young women who reported changes in pregnancy-related behaviors also had lower levels of study attrition, and completed more interviews overall, than did their counterparts. Conclusions We found that measures of participation in a longitudinal study with weekly web surveys varied not only by respondent characteristics, but also by behaviors measured across the surveys. Our analyses suggest that respondents who experience the behaviors measured by the study may maintain higher participation levels than respondents who do not experience those behaviors. PMID:27338859

Buspirone before prenatal stress protects against adverse effects of stress on emotional and inflammatory pain-related behaviors in infant rats: age and sex differences.

PubMed

Butkevich, Irina P; Mikhailenko, Viktor A; Vershinina, Elena A; Otellin, Vladimir A; Aloisi, Anna Maria

2011-10-24

Prenatal stress strengthens tonic pain and provokes depression. The serotoninergic system is involved in these processes. We recently showed that maternal buspirone, a 5-HT1A receptor agonist, protects against the adverse effects of in utero stress on depression and pain in adult rat offspring. Using a similar maternal treatment with buspirone, we focus here on the infant stage, which is important for the correction of prenatal abnormalities. Maternal buspirone before restraint stress during the last week of pregnancy decreased the time of immobility in the forced swim test in the infant offspring. Prenatal stress increased formalin-induced pain in the second part of the time-course of the response to formalin in males of middle infancy but in the first part of the response in males of late infancy. The effect was reversed by maternal buspirone. Pain dominated in males of both middle and late infancy but the time-course of formalin pain in infant females revealed a slower development of the processes. The results show that the time-course of formalin-induced pain in infant rats reacts to prenatal stress in an age-dependent and sexually dimorphic manner. Our finding of opposite influences of prenatal stress and buspirone before prenatal stress on formalin-induced pain during the interphase indicates that functional maturity of the descending serotonergic inhibitory system occurs in late infancy males (11-day-olds), and 5-HT1A receptors participate in this process. The data provide evidence that maternal treatment with buspirone prior to stress during pregnancy alleviates depression-like and tonic pain-related behaviors in the infant offspring. Copyright © 2011 Elsevier B.V. All rights reserved.

Genetic strain and diet effects on grazing behavior, pasture intake, and milk production.

PubMed

Sheahan, A J; Kolver, E S; Roche, J R

2011-07-01

Understanding how dairy cows adjust their grazing behavior in response to feed supplements is important for the development of management strategies that optimize profit from supplementation. New Zealand Holstein-Friesian (HF) cows have been selected for milk production on a predominantly pasture-based diet; in comparison, HF cows of North American (NA) ancestry have been selected almost exclusively for milk yield and fed diets high in nonfiber carbohydrates (NFC). We hypothesized, therefore, that supplementation would have differing effects on grazing behavior, pasture dry matter intake (DMI), and milk production in these genetic strains at peak, mid, and late lactation. A study was conducted over 2 consecutive lactations, with NA and NZ cows randomly allocated at calving to 0, 3, or 6 kg of dry matter/day concentrate plus unrestricted access to pasture. Pasture DMI, milk production, and grazing behavior were recorded at peak, mid, and late lactation. Concentrates were fed in equal amounts at morning and afternoon milking. The NA cows produced more milk and milk components, and had a greater pasture DMI, despite spending less time grazing. Declines in time spent grazing and pasture DMI were associated with increasing concentrate DMI. Grazing behavior following morning supplementation was different from that recorded following afternoon supplementation. Grazing ceased following morning supplementation before rumen fill could be a limiting factor, and the length of the grazing interval was inversely proportional to the amount of concentrate offered; these results suggest that physiological rather than physical stimuli were responsible for grazing cessation. The decrease in time spent grazing with increasing concentrate DMI is consistent with changes in neuroendocrine factors secreted in response to the presence of food in the digestive tract or with circulating products of digestion. After afternoon supplementation, sunset signaled the end of grazing irrespective of stage of lactation, timing of sunset, or supplementation status, suggesting that photoperiod influenced grazing behavior. Results confirmed changes in grazing behavior, an associated reduction in pasture DMI, and an increase in milk production when cows consume increasing amounts of concentrates. However, as the effect of supplement on grazing behavior differed between morning and afternoon supplementation, further research is required to better understand the factors controlling grazing behavior, to allow improved milk production responses to supplementary feeding. Copyright © 2011 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Seeing the partner: a video recall study of emotional behavior in same- and mixed-sex late adolescent romantic couples.

PubMed

Darling, Nancy; Clarke, Sara A

2009-08-01

Fifty-three college-aged same- and mixed-sex romantic couples (83% White, 63% female, mean age, 20.8) engaged in a video recall task in which they rated their own and their partners' behaviors and emotions. Females reported feeling more connected to partners and reported fewer negative behaviors than males. Females with male partners reported the highest feelings of connection and the fewest negative behaviors. Males with male partners reported the lowest connection and most negative behaviors. Behavioral mirroring and empathic accuracy did not vary by sex of the actor or of their partner. Partners' self-reported connection and negative behaviors were similar and they accurately perceived each others' average behavioral and emotional states. The data showed little evidence that partners' behaviors mirrored one another temporally across time segments, however. Results suggest that college-aged same and mixed-sex romantic couples show greater similarities than differences in functioning.

Transitions in Gambling Participation during Late Adolescence and Young Adulthood

PubMed Central

Bray, Bethany C.; Lee, Grace P.; Liu, Weiwei; Storr, Carla L.; Ialongo, Nicholas S.; Martins, Silvia S.

2014-01-01

Purpose The purpose of this study was to examine transitions in gambling participation from late adolescence into emerging adulthood, and to identify factors (i.e., gender, race, intervention status, lunch status, conduct disorder, parental monitoring, neighborhood environment, and substance use) that might influence these transitions. Methods Markov modeling was used to describe movement between past-year gambling states (i.e., non-gambling and gambling) over five years. Annual data on past-year gambling behavior and substance use were collected from 515 young men and women starting at age 17. Results Past-year gambling declined from 51% prevalence at age 17 to 21% prevalence at age 22. Participants who reported no past-year gambling at a particular annual assessment had more than an 80% probability of also reporting no past-year gambling at the following assessment. Men were 1.07–2.82 times more likely than women to transition from past-year non-gambling to gambling year-to-year, and women were 1.27–5.26 times more likely than men to transition from past-year gambling to non-gambling year-to-year. In addition, gender and past-year tobacco use interacted such that men who used tobacco were most likely (and men who did not use tobacco least likely) to gamble at baseline. Conclusions Transition rates between gambling states appear to be relatively stable over time from late adolescence into emerging adulthood; however, men and those who engage in substance use may be at increased risk for gambling participation. Implications and Contribution The current study provides important information about the naturalistic transitions in gambling behavior during late adolescence and emerging adulthood among an urban, mainly ethnic minority population. The finding that approximately half of past-year gamblers do not gamble during the following year suggests that gambling follows a variable developmental course. PMID:24656449

Physiological development and migratory behavior of subyearling fall chinook salmon in the Columbia River

USGS Publications Warehouse

Tiffan, K.F.; Rondorf, D.W.; Wagner, P.G.

2000-01-01

We describe the migratory behavior and physiological development of subyearling fall chinook salmon Oncorhynchus tshawytscha migrating through John Day Reservoir on the Columbia River, Washington and Oregon. Fish were freeze-branded and coded-wire-tagged at McNary Dam, Oregon, from 1991 to 1994, to determine travel time to John Day Dam and subsequent adult contribution. Stepwise multiple regression showed that 47% of the variation in subyearling fall chinook salmon travel time was explained by the reciprocal of minimum flow and fish size. Smoltification, as measured by gill Na+-K+ adenosine triphosphatase (ATPase) activity, was not important in explaining variability in travel time of subyearling chinook salmon. Fish marked early in the out-migration generally traveled faster than middle and late migrants. Seawater challenges were used to describe physiological development and showed that osmoregulatory competence of premigrants in the Hanford Reach of the Columbia River increased with fish size and gill ATPase activity. Once active migrants began passing McNary Dam, fish generally had survival exceeding 90% and were able to regulate their blood plasma Na+ in seawater. Gill ATPase activity increased as premigrants, reared in nearshore areas of the Hanford Reach, reached a peak among active migrants in late June and early July then decreased through the remainder of the out-migration. Salinity preference also peaked in subyearling fall chinook salmon during late June to mid July in 1995. Return of adults from marked groups showed no consistent patterns that would suggest a survival advantage for any portion of the juvenile out-migration. Presumed wild migrants from the middle and late portions of the out-migration were primary contributors to all fisheries, except the Priest Rapids Hatchery. As such, fishery managers should take action to ensure the survival of these fish, especially because they migrate under more unfavorable environmental conditions than early migrants.

Smoking, Screen-Based Sedentary Behavior, and Diet Associated with Habitual Sleep Duration and Chronotype: Data from the UK Biobank

PubMed Central

Patterson, Freda; Malone, Susan Kohl; Lozano, Alicia; Grandner, Michael A.; Hanlon, Alexandra L.

2016-01-01

Background Sleep duration has been implicated in the etiology of obesity but less is known about the association between sleep and other behavioral risk factors for cardiovascular disease. Purpose The aim of this study was to examine the associations among sleep duration, chronotype, and physical activity, screen-based sedentary behavior, tobacco use, and dietary intake. Methods Regression models were used to examine sleep duration and chronotype as the predictors and cardiovascular risk factors as outcomes of interest in a cross-sectional sample of 439,933 adults enrolled in the UK Biobank project. Results Short sleepers were 45 % more likely to smoke tobacco than adequate sleepers (9.8 vs. 6.9 %, respectively). Late chronotypes were more than twice as likely to smoke tobacco than intermediate types (14.9 vs. 7.4 %, respectively). Long sleepers reported 0.61 more hours of television per day than adequate sleepers. Early chronotypes reported 0.20 fewer daily hours of computer use per day than intermediate chronotypes. Early chronotypes had 0.25 more servings of fruit and 0.13 more servings of vegetables per day than late chronotypes. Conclusions Short and long sleep duration and late chronotype are associated with greater likelihood of cardiovascular risk behaviors. Further work is needed to determine whether these findings are maintained in the context of objective sleep and circadian estimates, and in more diverse samples. The extent to which promoting adequate sleep duration and earlier sleep timing improves heart health should also be examined prospectively. PMID:27056396

Dynamics of the functional link between area MT LFPs and motion detection

PubMed Central

Smith, Jackson E. T.; Beliveau, Vincent; Schoen, Alan; Remz, Jordana; Zhan, Chang'an A.

2015-01-01

The evolution of a visually guided perceptual decision results from multiple neural processes, and recent work suggests that signals with different neural origins are reflected in separate frequency bands of the cortical local field potential (LFP). Spike activity and LFPs in the middle temporal area (MT) have a functional link with the perception of motion stimuli (referred to as neural-behavioral correlation). To cast light on the different neural origins that underlie this functional link, we compared the temporal dynamics of the neural-behavioral correlations of MT spikes and LFPs. Wide-band activity was simultaneously recorded from two locations of MT from monkeys performing a threshold, two-stimuli, motion pulse detection task. Shortly after the motion pulse occurred, we found that high-gamma (100–200 Hz) LFPs had a fast, positive correlation with detection performance that was similar to that of the spike response. Beta (10–30 Hz) LFPs were negatively correlated with detection performance, but their dynamics were much slower, peaked late, and did not depend on stimulus configuration or reaction time. A late change in the correlation of all LFPs across the two recording electrodes suggests that a common input arrived at both MT locations prior to the behavioral response. Our results support a framework in which early high-gamma LFPs likely reflected fast, bottom-up, sensory processing that was causally linked to perception of the motion pulse. In comparison, late-arriving beta and high-gamma LFPs likely reflected slower, top-down, sources of neural-behavioral correlation that originated after the perception of the motion pulse. PMID:25948867

[Correlation between both neck/shoulder and low back pain and daily behavioral habits among middle school students in Shenzhen].

PubMed

Zhou, L; Huang, Y Y; Chen, D Y; Zhang, D; Luo, Q S; Wang, Y; Wu, Y

2018-04-10

Objective: To study the relations between neck/shoulder or low back pain and their daily behavioral habits among middle school students in Shenzhen. Methods: We randomly chose 3 952 students from 10 high schools in Shenzhen to complete the questionnaires. Data was gathered and analyzed, using the IBM SPSS 23.0. Results: Of the 3 952 participants, 20.3% had neck/shoulder pain and 15.2% had low back pain. Among students experienced neck/shoulder pain, female (25.3%), high school (24.5%) and boarding students (24.4%) experienced higher rates of neck/shoulder pain ( P <0.05). Female students (17.9%) also had higher rate of low back pain ( P <0.05). Results from logistic regression analysis showed that factors as: gender, type of school, taking naps on the desk, staying up late, self-perceived stress from learning, overloading homework, time spent on mobile phone and TV, spending long time on computer etc . were related to the neck/shoulder pain ( P <0.05). Factors as: gender, naps on the desk, stay up late, self-perceived stress, overloading homework, time spent on mobile phone and TV etc. , were related to low back pain ( P <0.05). Conclusion: Neck/shoulder pain and low back pain were both commonly seen while high self-perceived stress, sedentary behaviors and poor sleeping habits were associated with both neck/shoulder and low back pain in high school students in Shenzhen.

Experimental modelling of the consequences of brief late gestation asphyxia on newborn lamb behaviour and brain structure.

PubMed

Castillo-Melendez, Margie; Baburamani, Ana A; Cabalag, Carlos; Yawno, Tamara; Witjaksono, Anissa; Miller, Suzie L; Walker, David W

2013-01-01

Brief but severe asphyxia in late gestation or at the time of birth may lead to neonatal hypoxic ischemic encephalopathy and is associated with long-term neurodevelopmental impairment. We undertook this study to examine the consequences of transient in utero asphyxia in late gestation fetal sheep, on the newborn lamb after birth. Surgery was undertaken at 125 days gestation for implantation of fetal catheters and placement of a silastic cuff around the umbilical cord. At 132 days gestation (0.89 term), the cuff was inflated to induce umbilical cord occlusion (UCO), or sham (control). Fetal arterial blood samples were collected for assessment of fetal wellbeing and the pregnancy continued until birth. At birth, behavioral milestones for newborn lambs were recorded over 24 h, after which the lambs were euthanased for brain collection and histopathology assessments. After birth, UCO lambs displayed significant latencies to (i) use all four legs, (ii) attain a standing position, (iii) find the udder, and (iv) successfully suckle--compared to control lambs. Brains of UCO lambs showed widespread pathologies including cell death, white matter disruption, intra-parenchymal hemorrhage and inflammation, which were not observed in full term control brains. UCO resulted in some preterm births, but comparison with age-matched preterm non-UCO control lambs showed that prematurity per se was not responsible for the behavioral delays and brain structural abnormalities resulting from the in utero asphyxia. These results demonstrate that a single, brief fetal asphyxic episode in late gestation results in significant grey and white matter disruption in the developing brain, and causes significant behavioral delay in newborn lambs. These data are consistent with clinical observations that antenatal asphyxia is causal in the development of neonatal encephalopathy and provide an experimental model to advance our understanding of neuroprotective therapies.

Late-time structure of the Bunch-Davies de Sitter wavefunction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anninos, Dionysios; Anous, Tarek; Freedman, Daniel Z.

2015-11-30

We examine the late time behavior of the Bunch-Davies wavefunction for interacting light fields in a de Sitter background. We use perturbative techniques developed in the framework of AdS/CFT, and analytically continue to compute tree and loop level contributions to the Bunch-Davies wavefunction. We consider self-interacting scalars of general mass, but focus especially on the massless and conformally coupled cases. We show that certain contributions grow logarithmically in conformal time both at tree and loop level. We also consider gauge fields and gravitons. The four-dimensional Fefferman-Graham expansion of classical asymptotically de Sitter solutions is used to show that the wavefunctionmore » contains no logarithmic growth in the pure graviton sector at tree level. Finally, assuming a holographic relation between the wavefunction and the partition function of a conformal field theory, we interpret the logarithmic growths in the language of conformal field theory.« less

Dynamics of a barium release in the magnetospheric tail

NASA Technical Reports Server (NTRS)

Mende, S. B.; Swenson, G. R.; Geller, S. P.; Doolittle, J. H.; Haerendel, G.

1989-01-01

The late time behavior of the May 13, 1985 magnetotail barium cloud is examined. The bulk dynamics of the cloud are studied based on triangulated data and data from Fabry-Perot Doppler velocity measurements. The changes in cloud morphology in relation to the in situ measurements made by the Ion Release Module satellite are discussed.

A Comparative Study on Social Media Addiction of High School and University Students

ERIC Educational Resources Information Center

Simsek, Ali; Elciyar, Kemal; Kizilhan, Taner

2017-01-01

For a long time the concept of addiction has been considered within the medical context of consuming certain materials excessively. Lately, it has been used to describe by psychologists some behavioral habits that are outside the normal life of the general population, such as gambling which affect a particular group of individuals. After the…

Trajectories of Antisocial Behavior and Psychosocial Maturity from Adolescence to Young Adulthood

ERIC Educational Resources Information Center

Monahan, Kathryn C.; Steinberg, Laurence; Cauffman, Elizabeth; Mulvey, Edward P.

2009-01-01

Most theorizing about desistance from antisocial behavior in late adolescence has emphasized the importance of individuals' transition into adult roles. In contrast, little research has examined how psychological development in late adolescence and early adulthood contributes desistance. The present study examined trajectories of antisocial…

Conflict Beliefs, Goals, and Behavior in Romantic Relationships during Late Adolescence

ERIC Educational Resources Information Center

Simon, Valerie A.; Kobielski, Sarah J.; Martin, Sarah

2008-01-01

Little is known about social cognition regarding conflict in romantic relationships during late adolescence. The current study examined beliefs, social goals, and behavioral strategies for conflict in romantic relationships and their associations with relationship quality among a sample of 494 college students. Two dimensions of conflict beliefs,…

Nonresident Fathers' Parenting Style and the Adjustment of Late-Adolescent Boys

ERIC Educational Resources Information Center

Karre, Jennifer K.; Mounts, Nina S.

2012-01-01

This study investigates the relation between nonresident fathers' parenting style, mothers' parenting style and behaviors, and depression and antisocial behavior in a sample of late-adolescent boys (n = 177). Hierarchical regression analyses were performed. Maternal psychological well-being was associated with fewer adolescent depression symptoms.…

N400 Event-Related Potential and Standardized Measures of Reading in Late Elementary School Children: Correlated or Independent?

ERIC Educational Resources Information Center

Coch, Donna; Benoit, Clarisse

2015-01-01

We investigated whether and how standardized behavioral measures of reading and electrophysiological measures of reading were related in 72 typically developing, late elementary school children. Behavioral measures included standardized tests of spelling, phonological processing, vocabulary, comprehension, naming speed, and memory.…

LATE GESTATIONAL ATRAZINE EXPOSURE DECREASES MATERNAL BEHAVIOR IN LONG-EVANS RATS

EPA Science Inventory

Late Gestational Atrazine Exposure Alters Maternal Nursing Behavior in Rats

Jennifer L. Rayner1 and Suzanne E. Fenton2

1 University of North Carolina at Chapel Hill, DESE, Chapel Hill, NC, and 2 USEPA/ ORD/NHEERL/Reproductive Toxicology Division, RTP, NC.

At...

Complex response of a midcontinent north America drainage system to late Wisconsinan sedimentation

USGS Publications Warehouse

Bettis, E. Arthur; Autin, W.J.

1997-01-01

The geomorphic evolution of Mud Creek basin in eastern Iowa, U.S.A. serves to illustrate how geomorphic influences such as sediment supply, valley gradient, climate, and vegetation are recorded in the alluvial stratigraphic record. Sediment supply to the fluvial system increased significantly during the late Wisconsinan through a combination of periglacial erosion and loess accumulation. Subsequent evolution of the Holocene alluvial stratigraphic record reflects long-term routing of the late Wisconsinan sediment through the drainage basin in a series of cut-and-fill cycles whose timing was influenced by hydrologic response to change in climate and vegetation. When viewed in a regional context, the alluvial stratigraphic record appears to reflect a long-term complex response of the fluvial system to increased sediment supply during the late Wisconsinan. Hydrologic and sediment-supply changes accompanying the spread of Euroamerican agriculture to the basin in the 180Os dramatically upset trends in sedimentation and channel behavior established during the Holocene. Copyright ?? 1997, SEPM (Society for Sedimentary Geology).

Mediation of late adolescent health-risk behaviors and gender influences.

PubMed

Christopherson, Toni Michelle; Conner, Bradley T

2012-11-01

This study explored how multiple bioecological constructs operate to explain health-risk behaviors in late adolescence and to test for moderator effects of gender. This was a descriptive, cross-sectional study with a convenience sample of 437 predominately Caucasian late adolescents with an average age of 19 years who lived in Northern California. Parental Attachment, Shyness, Loneliness, Law Abidance, and Youth Risk Behaviors were measured with self-report tools and analyzed using structural equation modeling. Confirmatory factor analysis indicated that the data fit the model well. Analysis of group differences revealed that gender moderated the relationships among the measured variables; thus, data were analyzed in independent gender-based models. Structural modeling demonstrated good model fit for each gender. Shyness and parental attachment each were associated with loneliness. Loneliness was associated with smoking. Loneliness linked the relationship between shyness, parental attachment, and smoking. Parental attachment was associated with law abidance. Law abidance was associated with sexual behaviors for female adolescents only. This study provides valuable insights for public health nurses as it pertains to late adolescent health-risk behaviors. Nurses should use screening tools and techniques to ensure appropriate referrals and interventions to meet the needs of at-risk adolescents. © 2012 Wiley Periodicals, Inc.

Modification of the effects of 5-methoxy-N,N-dimethyltryptamine on exploratory behavior in rats by monoamine oxidase inhibitors

PubMed Central

Halberstadt, Adam L.; Buell, Mahalah R.; Masten, Virginia L.; Risbrough, Victoria B.; Geyer, Mark A.

2010-01-01

RATIONALE The hallucinogenic tea known as ayahuasca is made from a combination of psychoactive plants that contribute the active components N,N-dimethyltryptamine (DMT) and 5-methoxy-DMT (5-MeO-DMT), as well as the monoamine oxidase (MAO) inhibitors (MAOIs) harmine and harmaline for oral activity. OBJECTIVE The present study examined the effects of 5-MeO-DMT in combination with MAOIs in rats using the Behavioral Pattern Monitor (BPM), which enables analyses of patterns of locomotor activity and exploration. Interaction studies using the serotonin (5-HT)1A antagonist WAY-100635 (1.0 mg/kg) and the 5-HT2A antagonist MDL 11,939 (1.0 mg/kg) were also performed to assess the respective contributions of these receptors to the behavioral effects of 5-MeO-DMT in MAOI-treated animals. RESULTS 5-MeO-DMT (0.01, 0.1, and 1.0 mg/kg) decreased locomotor activity and investigatory behavior. In rats pretreated with a behaviorally inactive dose of harmaline (0.1 mg/kg), 1.0 mg/kg 5-MeO-DMT had biphasic effects on locomotor activity, initially reducing locomotion and then increasing activity as time progressed. The ability of harmaline to shift 5-MeO-DMT to a biphasic locomotor pattern was shared by the selective MAOA inhibitor clorgyline, whereas the selective MAOB inhibitor (−)-deprenyl was ineffective. The late hyperactivity induced by the combination of 1.0 mg/kg 5-MeO-DMT and 0.3 mg/kg clorgyline was blocked by pretreatment with MDL 11,939. Pretreatment with WAY-100635 failed to attenuate either the early hypoactivity or the late hyperactivity. CONCLUSIONS The ability of harmaline to modify the behavioral effects of 5-MeO-DMT is mediated by inhibition of MAOA. Further, 5-HT2A receptors are responsible for the late hyperactivity induced by 5-MeO-DMT in the presence of MAOA inhibitors. PMID:18604652

Modification of the effects of 5-methoxy-N,N-dimethyltryptamine on exploratory behavior in rats by monoamine oxidase inhibitors.

PubMed

Halberstadt, Adam L; Buell, Mahalah R; Masten, Virginia L; Risbrough, Victoria B; Geyer, Mark A

2008-11-01

The hallucinogenic tea known as ayahuasca is made from a combination of psychoactive plants that contribute the active components N,N-dimethyltryptamine (DMT) and 5-methoxy-DMT (5-MeO-DMT), as well as the monoamine oxidase (MAO) inhibitors (MAOIs) harmine and harmaline for oral activity. The present study examined the effects of 5-MeO-DMT in combination with MAOIs in rats using the behavioral pattern monitor, which enables analyses of patterns of locomotor activity and exploration. Interaction studies using the serotonin (5-HT)(1A) antagonist WAY-100635 (1.0 mg/kg) and the 5-HT(2A) antagonist MDL 11,939 (1.0 mg/kg) were also performed to assess the respective contributions of these receptors to the behavioral effects of 5-MeO-DMT in MAOI-treated animals. 5-MeO-DMT (0.01, 0.1, and 1.0 mg/kg) decreased locomotor activity and investigatory behavior. In rats pretreated with a behaviorally inactive dose of harmaline (0.1 mg/kg), 1.0 mg/kg 5-MeO-DMT had biphasic effects on locomotor activity, initially reducing locomotion and then increasing activity as time progressed. The ability of harmaline to shift 5-MeO-DMT to a biphasic locomotor pattern was shared by the selective MAO(A) inhibitor clorgyline, whereas the selective MAO(B) inhibitor (-)-deprenyl was ineffective. The late hyperactivity induced by the combination of 1.0 mg/kg 5-MeO-DMT and 0.3 mg/kg clorgyline was blocked by pretreatment with MDL 11,939. Pretreatment with WAY-100635 failed to attenuate either the early hypoactivity or the late hyperactivity. The ability of harmaline to modify the behavioral effects of 5-MeO-DMT is mediated by the inhibition of MAO(A). Furthermore, 5-HT(2A) receptors are responsible for the late hyperactivity induced by 5-MeO-DMT in the presence of MAO(A) inhibitors.

Developmental subchronic exposure to diphenylarsinic acid induced increased exploratory behavior, impaired learning behavior, and decreased cerebellar glutathione concentration in rats.

PubMed

Negishi, Takayuki; Matsunaga, Yuki; Kobayashi, Yayoi; Hirano, Seishiro; Tashiro, Tomoko

2013-12-01

In Japan, people using water from the well contaminated with high-level arsenic developed neurological, mostly cerebellar, symptoms, where diphenylarsinic acid (DPAA) was a major compound. Here, we investigated the adverse effects of developmental exposure to 20mg/l DPAA in drinking water (early period [0-6 weeks of age] and/or late period [7-12]) on behavior and cerebellar development in male rats. In the open field test at 6 weeks of age, early exposure to DPAA significantly increased exploratory behaviors. At 12 weeks of age, late exposure to DPAA similarly increased exploratory behavior independent of the early exposure although a 6-week recovery from DPAA could reverse that change. In the passive avoidance test at 6 weeks of age, early exposure to DPAA significantly decreased the avoidance performance. Even at 12 weeks of age, early exposure to DPAA significantly decreased the test performance, which was independent of the late exposure to DPAA. These results suggest that the DPAA-induced increase in exploratory behavior is transient, whereas the DPAA-induced impairment of passive avoidance is long lasting. At 6 weeks of age, early exposure to DPAA significantly reduced the concentration of cerebellar total glutathione. At 12 weeks of age, late, but not early, exposure to DPAA also significantly reduced the concentration of cerebellar glutathione, which might be a primary cause of oxidative stress. Early exposure to DPAA induced late-onset suppressed expression of NMDAR1 and PSD95 protein at 12 weeks of age, indicating impaired glutamatergic system in the cerebellum of rats developmentally exposed to DPAA.

Effect of moving dairy cows at different stages of labor on behavior during parturition.

PubMed

Proudfoot, K L; Jensen, M B; Heegaard, P M H; von Keyserlingk, M A G

2013-03-01

Cows are often moved from a group to an individual maternity pen just before calving. However, it is unclear whether moving cows during labor may alter their behavior or affect the progress of labor. The aim of this study was to determine if moving cows to a maternity pen at different stages of labor would influence calving behavior or the length of the second stage of labor. Seventy-nine multiparous Holstein dairy cows were moved from 1 of 2 group pens to 1 of 10 maternity pens adjacent to each group pen either 3 d before expected calving date or when one or more behavioral or physical signs of labor were observed. These signs were noted, and were used to retrospectively categorize cows into 1 of 3 movement categories: (1) moved before labor, (2) moved during early stage I labor (signs of suddenly tense and enlarged udder, raised tail or relaxed pelvic ligaments; could also be immediately prelabor), or (3) moved during late stage I labor (signs of viscous, bloody mucus or abdominal contractions; could also be transitioning to stage II labor). Calves were weighed within 12h of birth and remained with their dam for 3 d. The length of the second stage of labor (the time between first abdominal contractions to the delivery the calf) and the total time of abdominal contractions, lying time, and number of position changes from standing to lying made by the cow in the hour before calving were recorded. A single blood sample was taken from the jugular vein of cows 3 to 27 h after calving to determine content of haptoglobin, a marker of systemic inflammation. The effect of movement category on length of the second stage of labor and behavioral variables was tested with ANOVA; category was a fixed effect and calf body weight (BW) and cow parity were covariates. The relationship between haptoglobin and the length of the second stage of labor was tested in a model with time of sampling relative to calving as a covariate. Cows moved during late stage I had the longest labor, but did not have longer contractions compared with cows in the other categories. These same cows spent half as much time lying in the 1h before calving compared with cows in the other categories, but did not differ in the number of position changes from standing to lying. We did not have the power to test the effect of movement category on haptoglobin, but cows with longer stage II labor had higher haptoglobin postcalving. Moving cows to a maternity pen during the late part of the first stage of labor caused a delay in the second stage of labor, and this was likely driven by altered lying behavior. Copyright © 2013 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

General and food-specific inhibitory deficits in binge eating disorder.

PubMed

Svaldi, Jennifer; Naumann, Eva; Trentowska, Monika; Schmitz, Florian

2014-07-01

To investigate behavioral inhibition in individuals with binge eating disorder (BED) compared with overweight and obese individuals without BED (No-BED). Participants with BED (n = 31) and the weight-matched No-BED group (n = 29) completed an inhibitory control task (stop-signal task, SST) with food and neutral stimuli. The BED group needed more time to stop an ongoing response, as indicated by increased stop signal reaction time (SSRT) relative to the No-BED group. Additionally, compared with the No-BED group, the BED group displayed more difficulty inhibiting responses elicited by food stimuli. The deficits in behavioral response inhibition were also found to be related to the severity of reported symptoms. There is a general deficit in late stage behavioral inhibition in BED, and this may be particularly pronounced in the context of food stimuli. © 2014 Wiley Periodicals, Inc.

Activation of the maternal immune system during pregnancy alters behavioral development of rhesus monkey offspring.

PubMed

Bauman, Melissa D; Iosif, Ana-Maria; Smith, Stephen E P; Bregere, Catherine; Amaral, David G; Patterson, Paul H

2014-02-15

Maternal infection during pregnancy is associated with an increased risk of schizophrenia and autism in the offspring. Supporting this correlation, experimentally activating the maternal immune system during pregnancy in rodents produces offspring with abnormal brain and behavioral development. We have developed a nonhuman primate model to bridge the gap between clinical populations and rodent models of maternal immune activation (MIA). A modified form of the viral mimic, synthetic double-stranded RNA (polyinosinic:polycytidylic acid stabilized with poly-L-lysine) was delivered to two separate groups of pregnant rhesus monkeys to induce MIA: 1) late first trimester MIA (n = 6), and 2) late second trimester MIA (n = 7). Control animals (n = 11) received saline injections at the same first or second trimester time points or were untreated. Sickness behavior, temperature, and cytokine profiles of the pregnant monkeys confirmed a strong inflammatory response to MIA. Behavioral development of the offspring was studied for 24 months. Following weaning at 6 months of age, MIA offspring exhibited abnormal responses to separation from their mothers. As the animals matured, MIA offspring displayed increased repetitive behaviors and decreased affiliative vocalizations. When evaluated with unfamiliar conspecifics, first trimester MIA offspring deviated from species-typical macaque social behavior by inappropriately approaching and remaining in immediate proximity of an unfamiliar animal. In this rhesus monkey model, MIA yields offspring with abnormal repetitive behaviors, communication, and social interactions. These results extended the findings in rodent MIA models to more human-like behaviors resembling those in both autism and schizophrenia. Copyright © 2014 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

Patients with late-adult-onset ulcerative colitis have better outcomes than those with early onset disease.

PubMed

Ha, Christina Y; Newberry, Rodney D; Stone, Christian D; Ciorba, Matthew A

2010-08-01

The influence of age on the presentation, clinical course, and therapeutic response of patients with adult-onset ulcerative colitis (UC) is understudied. Given potential age-related differences in risk factors and immune function, we sought to determine if disease behavior or clinical outcomes differed between patients diagnosed with UC in later versus earlier stages of adulthood. We performed a retrospective cohort study of 295 patients with UC seen at a tertiary care center from 2001 to 2008. Adult subjects newly diagnosed with UC between the ages of 18 and 30 years were defined as early onset, those newly diagnosed at age 50 or older were defined as late onset. The 2 groups were analyzed for differences in medication use and clinical end points, including disease extent, severity at the time of diagnosis, and steroid-free clinical remission at 1 year after disease onset. Disease extent and symptom severity were similar between groups at the time of diagnosis. One year after diagnosis, more patients in the late-onset group achieved steroid-free clinical remission (64% vs 49%; P = .01). Among those who required systemic steroid therapy, more late-onset patients achieved steroid-free remission by 1 year (50% vs 32%; P = .01). Former smoking status was a more common risk factor in the late-onset cohort (P < .001), whereas more early onset patients had a positive family history (P = .008). Patients with early and late-adult-onset UC have similar initial clinical presentations, but differ in disease risk factors. Late-onset patients have better responses to therapy 1 year after diagnosis. Copyright 2010 AGA Institute. Published by Elsevier Inc. All rights reserved.

Dysfunctional Relationship Beliefs in Parent-Late Adolescent Relationship and Conflict Resolution Behaviors

ERIC Educational Resources Information Center

Hamamci, Zeynep

2007-01-01

The purpose of this study is to investigate the role of dysfunctional relationships beliefs on both the perceptions of their relationships with the parents and conflict resolution behaviors of late adolescence. The sample was consisted of 372 Turkish university students (248 women and 124 men). Interpersonal Cognitive Distortions Scale,…

Other-Sex Friendships in Late Adolescence: Risky Associations for Substance Use and Sexual Debut?

ERIC Educational Resources Information Center

Mrug, Sylvie; Borch, Casey; Cillessen, Antonius H. N.

2011-01-01

Adolescents' friendships with other-sex peers serve important developmental functions, but they may also facilitate engagement in problem behavior. This study examines the unique contributions of other-sex friendships and friends' behavior to alcohol use, smoking, and initiation of sexual intercourse among late adolescent girls and boys. A total…

Novel observations of larval fire survival, feeding behavior, and host plant use in the regal fritillary, Speyeria idalia (Drury) (Nymphalidae)

USGS Publications Warehouse

McCullough, Kelsey; Albanese, Gene; Haukos, David A.

2017-01-01

Speyeria idalia is a prairie specialist that has experienced dramatic population declines throughout its range. Speyeria idalia is nearly extirpated from the eastern portion of its former range; however, populations within Kansas are relatively stable. We made several previously undescribed field observations of late-instar larvae and post-diapause female S. idalia in northeastern Kansas during 2014–2016. We report finding late-instar larvae at locations that were burned within weeks of detection. The observations of larvae shortly following a burn suggests that S. idalia larvae are capable of surviving fire and contradicts our current knowledge of this species. Additionally, we describe a feeding behavior characteristic of late-instar larvae. Larvae observed in the field and lab stripped leaves of host plants leaving only stems. This strip-style feeding behavior provided unique feeding evidence that was valuable to detecting the presence of larvae in the field. Finally, we documented larvae and post-diapause, egg depositing females using Viola sororia. The use of this relatively widespread and common plant by S. idalia populations in the Central Great Plains has only been implicitly documented but may have important conservation implications. These novel observations further our knowledge of the ecology of this imperiled species and provide timely information that may improve research and conservation management efforts directed toward S. idalia populations.

On early starters and late bloomers: the development of sexual behavior in adolescence across personality types.

PubMed

Baams, Laura; Overbeek, Geertjan; Dubas, Judith Semon; van Aken, Marcel A G

2014-01-01

Little is known about the relationship between personality and sexual development among mid-adolescents. In the current study, we used a person-centered approach to investigate the relation between personality types and the development of sexual behavior. We hypothesized that undercontrolling adolescents would engage in more advanced, casual, and risky sexual behavior compared to their resilient and overcontrolling peers. Data were used from 407 mid-adolescents (Mage = 14.5) followed across four measurement waves spanning 18 months. Results from latent class analyses (LCA) identified the three classical personality types: resilients, undercontrollers, and overcontrollers. Controlling for perceived pubertal timing and biological sex, latent growth curve analyses in Mplus showed that, at baseline, undercontrollers were more sexually experienced and engaged in more casual and risky sexual behavior than resilients and overcontrollers. Although initial levels of sexual behavior differed by personality types, over time increases in sexual behavior occurred at a similar rate across the types. Overall, the current study showed that undercontrolling adolescents are early sexual developers who engage in more advanced, casual, and risky sexual behavior than other adolescents. The implications of these findings for longer-term differences in sexual behavior between personality types in later adolescence are discussed.

Mapping the Speech Code: Cortical Responses Linking the Perception and Production of Vowels

PubMed Central

Schuerman, William L.; Meyer, Antje S.; McQueen, James M.

2017-01-01

The acoustic realization of speech is constrained by the physical mechanisms by which it is produced. Yet for speech perception, the degree to which listeners utilize experience derived from speech production has long been debated. In the present study, we examined how sensorimotor adaptation during production may affect perception, and how this relationship may be reflected in early vs. late electrophysiological responses. Participants first performed a baseline speech production task, followed by a vowel categorization task during which EEG responses were recorded. In a subsequent speech production task, half the participants received shifted auditory feedback, leading most to alter their articulations. This was followed by a second, post-training vowel categorization task. We compared changes in vowel production to both behavioral and electrophysiological changes in vowel perception. No differences in phonetic categorization were observed between groups receiving altered or unaltered feedback. However, exploratory analyses revealed correlations between vocal motor behavior and phonetic categorization. EEG analyses revealed correlations between vocal motor behavior and cortical responses in both early and late time windows. These results suggest that participants' recent production behavior influenced subsequent vowel perception. We suggest that the change in perception can be best characterized as a mapping of acoustics onto articulation. PMID:28439232

Grazing behavior and production characteristics among cows differing in residual feed intake while grazing late season Idaho rangeland

USDA-ARS?s Scientific Manuscript database

The objectives were to determine if cows classified as either low- or high-residual feed intake (LRFI or HRFI) differed in BW, BCS, and winter grazing activity over time. Thirty Hereford x Angus (LRFI = 16; HRFI = 14) 2-year-old cows grazed sagebrush-steppe for 78 d beginning 29 September 2016. Body...

The Risks and Rewards of Sexual Debut

PubMed Central

Golden, Rachel Lynn; Furman, Wyndol; Collibee, Charlene

2016-01-01

The sex-positive framework of sexual development hypothesizes that healthy sexual experiences can be developmentally appropriate and rewarding for adolescents despite the risks involved. Research has not examined whether risky behaviors and rewarding cognitions actually change with sexual debut at a normative or late age. This study measured the longitudinal impact of sexual debut using 7 waves of data from 88 male and 86 female adolescents from a Western U.S. city who were in the 10th grade at the study’s onset. We used piecewise growth curve analyses to compare behavior and cognitions before and after first sexual intercourse for those whose debut was at a normative or late age. These analyses revealed that sexual debut was related to rewards including increases in romantic appeal, and sexual satisfaction. In addition, internalizing symptoms declined over time after sexual debut, and substance use grew at a slower rate after sexual debut. We also examined whether differences existed among those whose debut was at an early, normative, or late age. Linear growth curve analyses revealed early sexual debut was related to risks, such as greater substance use, more internalizing and externalizing symptoms and lower global self-worth. Rewards associated with an early debut included greater romantic appeal, dating satisfaction (males only), and sexual satisfaction (males only). Although there are some inherent risks with sexual activity, the results suggest that sexual debut at a normative or late age is also associated with a decrease in some risks and increase in rewards. PMID:27709996

Reprint of "Repeated adolescent activity-based anorexia influences central estrogen signaling and adulthood anxiety-like behaviors in rats".

PubMed

Lee, Tien-Jui; Kinzig, Kimberly P

2017-09-01

Anorexia nervosa (AN) typically presents in adolescence and is highly comorbid with anxiety and depression, which often persist after elimination of AN symptomology. The activity-based anorexia (ABA) paradigm allows for evaluation of behavioral and neuroendocrine consequences of AN-like behaviors, including voluntary anorexia, hyperactivity, and disruption of the hypothalamic-pituitary-gonadal (HPG) and the hypothalamic pituitary adrenal (HPA) axis. Because ABA in adolescent females results in increased anxiety-like behavior in adulthood and the estrogen signaling system has been shown to play a role in anxiety and food intake, we investigated the role of ovarian hormones in adolescent ABA-treated rats, and long-term effects of mid- and late adolescent ABA exposure on behavior and estrogen signaling. While previous research demonstrated that two bouts of ABA during adolescence resulted in decreased time in the open arm of the elevated plus maze (EPM) and increased activity of the HPA axis in response to a novel stressor, here we show that one bout of ABA in mid-or late-adolescence did not result in the same behavioral outcome. Two exposures to ABA during adolescence were necessary to produce long-term anxiety-like behavior on the EPM. Finally, removal of ovarian hormones by ovariectomy (OVX) prior to puberty did not attenuate long-term behavioral consequences of ABA in adolescence, and estrogen receptor β (ERβ) expression level in the amygdala of ABA rats was significantly lower than control subjects. Taken together, these studies identify enduring effects of ABA in adolescent females that may be mediated by ABA-induced changes to CNS ERβ signaling that increase anxiety-like behaviors. Copyright © 2017 Elsevier Inc. All rights reserved.

Age, sex, and gonadal hormones differently influence anxiety- and depression-related behavior during puberty in mice.

PubMed

Boivin, Josiah R; Piekarski, David J; Wahlberg, Jessica K; Wilbrecht, Linda

2017-11-01

Anxiety and depression symptoms increase dramatically during adolescence, with girls showing a steeper increase than boys after puberty onset. The timing of the onset of this sex bias led us to hypothesize that ovarian hormones contribute to depression and anxiety during puberty. In humans, it is difficult to disentangle direct effects of gonadal hormones from social and environmental factors that interact with pubertal development to influence mental health. To test the role of gonadal hormones in anxiety- and depression-related behavior during puberty, we manipulated gonadal hormones in mice while controlling social and environmental factors. Similar to humans, we find that mice show an increase in depression-related behavior from pre-pubertal to late-pubertal ages, but this increase is not dependent on gonadal hormones and does not differ between sexes. Anxiety-related behavior, however, is more complex during puberty, with differences that depend on sex, age, behavioral test, and hormonal status. Briefly, males castrated before puberty show greater anxiety-related behavior during late puberty compared to intact males, while pubertal females are unaffected by ovariectomy or hormone injections in all assays except the marble burying test. Despite this sex-specific effect of pubertal hormones on anxiety-related behavior, we find no sex differences in intact young adults, suggesting that males and females use separate mechanisms to converge on a similar behavioral phenotype. Our results are consistent with anxiolytic effects of testicular hormones during puberty in males but are not consistent with a causal role for ovarian hormones in increasing anxiety- and depression-related behavior during puberty in females. Copyright © 2017 Elsevier Ltd. All rights reserved.

Relation between premorbid personality and patterns of emotion expression in mid- to late-stage dementia.

PubMed

Magai, C; Cohen, C I; Culver, C; Gomberg, D; Malatesta, C

1997-11-01

Twenty-seven nursing home patients with mid- to late-stage dementia participated in a study of the relation between preillness personality, as indexed by attachment and emotion regulation style, and current emotional behavior. Preillness measures were completed by family members and current assessments of emotion were supplied by nursing home aides and family members; in addition, emotion was coded during a family visit using an objective coding system for facial emotion expressions. Attachment style was found to be related to the expression of positive affect, with securely attached individuals displaying more positive affect than avoidantly attached individuals. In addition, high ratings on premorbid hostility were associated with higher rates of negative affect and lower rates of positive affect. These findings indicate that premorbid aspects of personality show continuity over time, even in mid- to late-stage dementia.

Mediators of the Associations between Externalizing Behaviors and Internalizing Symptoms in Late Childhood and Early Adolescence

ERIC Educational Resources Information Center

Yong, Minglee; Fleming, Charles B.; McCarty, Carolyn A.; Catalano, Richard F.

2014-01-01

This study tests the predictive associations between externalizing behaviors and internalizing symptoms and examines the mediating roles of social competence, parent-child conflicts, and academic achievement. Using youth-, parent-, and teacher-reported longitudinal data on a sample of 523 boys and 460 girls from late childhood to early…

Brief Report: Direct and Indirect Relations of Risk Factors with Eating Behavior Problems in Late Adolescent Females

ERIC Educational Resources Information Center

Mayer, Birgit; Muris, Peter; Meesters, Cor; Zimmermann-van Beuningen, Ritine

2009-01-01

This study explored correlations between risk factors and eating behavior problems in late adolescent, non-clinical females (N = 301). Participants completed questionnaires for assessing eating problems, the closely associated factors of Body Mass Index (BMI) and body dissatisfaction, and a number of other risk variables that are thought to be…

Extending Cognitive-Behavioral Therapy for Late-Life Anxiety to Home Care: Program Development and Case Examples

ERIC Educational Resources Information Center

Diefenbach, Gretchen J.; Tolin, David F.; Gilliam, Christina M.; Meunier, Suzanne A.

2008-01-01

Data suggesting that cognitive-behavioral therapy (CBT) is efficacious for late-life anxiety are accumulating; however, effectiveness has not been well established. Incorporating CBT for anxiety into home care is needed to facilitate access to evidenced-based treatment for a growing population of community-dwelling, functionally impaired elderly…

Integrating Religion and Spirituality into Treatment for Late-Life Anxiety: Three Case Studies

ERIC Educational Resources Information Center

Barrera, Terri L.; Zeno, Darrell; Bush, Amber L.; Barber, Catherine R.; Stanley, Melinda A.

2012-01-01

Generalized anxiety disorder (GAD) is common in older adults and, although cognitive behavioral therapy (CBT) is an efficacious treatment for late-life GAD, effect sizes are only moderate and attrition rates are high. One way to increase treatment acceptability and enhance current cognitive behavioral treatments for GAD in older adults might be to…

The Developmental Trajectories of Peer Victimization in Middle to Late Childhood and the Changing Nature of Their Behavioral Correlates

ERIC Educational Resources Information Center

Boivin, Michel; Petitclerc, Amelie; Feng, Bei; Barker, Edward D.

2010-01-01

This study investigated the evolving relations between peer victimization and social/emotional difficulties in middle to late childhood. Peer assessments of peer victimization and social/emotional difficulties (aggressive behavior, social withdrawal, and emotional vulnerability) were collected over 4 years for 1,035 children attending Grades 3-6…

Developmental Subchronic Exposure to Diphenylarsinic Acid Induced Increased Exploratory Behavior, Impaired Learning Behavior, and Decreased Cerebellar Glutathione Concentration in Rats

PubMed Central

Negishi, Takayuki; Matsunaga, Yuki

2013-01-01

In Japan, people using water from the well contaminated with high-level arsenic developed neurological, mostly cerebellar, symptoms, where diphenylarsinic acid (DPAA) was a major compound. Here, we investigated the adverse effects of developmental exposure to 20mg/l DPAA in drinking water (early period [0–6 weeks of age] and/or late period [7–12]) on behavior and cerebellar development in male rats. In the open field test at 6 weeks of age, early exposure to DPAA significantly increased exploratory behaviors. At 12 weeks of age, late exposure to DPAA similarly increased exploratory behavior independent of the early exposure although a 6-week recovery from DPAA could reverse that change. In the passive avoidance test at 6 weeks of age, early exposure to DPAA significantly decreased the avoidance performance. Even at 12 weeks of age, early exposure to DPAA significantly decreased the test performance, which was independent of the late exposure to DPAA. These results suggest that the DPAA-induced increase in exploratory behavior is transient, whereas the DPAA-induced impairment of passive avoidance is long lasting. At 6 weeks of age, early exposure to DPAA significantly reduced the concentration of cerebellar total glutathione. At 12 weeks of age, late, but not early, exposure to DPAA also significantly reduced the concentration of cerebellar glutathione, which might be a primary cause of oxidative stress. Early exposure to DPAA induced late-onset suppressed expression of NMDAR1 and PSD95 protein at 12 weeks of age, indicating impaired glutamatergic system in the cerebellum of rats developmentally exposed to DPAA. PMID:24008832

Anisotropic ghost dark energy cosmological model with hybrid expansion law

NASA Astrophysics Data System (ADS)

Mahanta, Chandra Rekha; Sarma, Nitin

2017-11-01

In this paper, we study the anisotropic Bianchi type-VI0 metric filled with dark matter and anisotropic ghost dark energy. We have solved the Einstein's field equations by considering hybrid expansion law (HEL) for the average scale factor. It is found that at later times the universe becomes spatially homogeneous, isotropic and flat. From a state finder diagnosis, it is found that our model is having similar behavior like ɅCDM model at late phase of cosmic time.

Factors Associated with the Time of Admission among Notified Dengue Fever Cases in Region VIII Philippines from 2008 to 2014

PubMed Central

Gil Cuesta, Julita; Cerro, Boyd Roderick; Guha-Sapir, Debarati

2016-01-01

In cases of Dengue fever, late hospital admission can lead to treatment delay and even death. In order to improve early disease notification and management, it is essential to investigate the factors affecting the time of admission of Dengue cases. This study determined the factors associated with the time of admission among notified Dengue cases. The study covered the period between 2008 and 2014 in Region VIII, Philippines. The factors assessed were age, sex, hospital sector, hospital level, disease severity based on the 1997 WHO Dengue classification, and period of admission (distinguishing between the 2010 Dengue epidemic and non-epidemic time). We analysed secondary data from the surveillance of notified Dengue cases. We calculated the association through chi-square test, ordinal logistic regression and linear regression at p value < 0.05. The study included 16,357 admitted Dengue cases. The reported cases included a majority of children (70.09%), mild cases of the disease (64.00%), patients from the public sector (69.82%), and non-tertiary hospitals (62.76%). Only 1.40% of cases had a laboratory confirmation. The epidemic period in 2010 comprised 48.68% of all the admitted cases during this period. Late admission was more likely among adults than children (p<0.05). The severe type of the disease was more likely to be admitted late than the mild type (p<0.05). Late admission was also more likely in public hospitals than in private hospitals (p<0.05); and within tertiary level hospitals than non-tertiary hospitals (p<0.05). Late admission was more likely during the non-epidemic period than the 2010 epidemic period (p<0.05). A case fatality rate of 1 or greater was significantly associated with children, severe diseases, tertiary hospitals and public hospitals when admitted late (p<0.05). Data suggests that early admission among child cases was common in Region VIII. This behavior is encouraging, and should be continued. However, further study is needed on the late admission among tertiary, public hospitals and non-epidemic period with reference to the quality of care, patient volume, out of pocket expense, and accessibility We recommend the consistent use of the 2009 WHO Dengue guidelines in order to standardize the admission criteria and time across hospitals. PMID:27780199

Neocortical Rebound Depolarization Enhances Visual Perception

PubMed Central

Funayama, Kenta; Ban, Hiroshi; Chan, Allen W.; Matsuki, Norio; Murphy, Timothy H.; Ikegaya, Yuji

2015-01-01

Animals are constantly exposed to the time-varying visual world. Because visual perception is modulated by immediately prior visual experience, visual cortical neurons may register recent visual history into a specific form of offline activity and link it to later visual input. To examine how preceding visual inputs interact with upcoming information at the single neuron level, we designed a simple stimulation protocol in which a brief, orientated flashing stimulus was subsequently coupled to visual stimuli with identical or different features. Using in vivo whole-cell patch-clamp recording and functional two-photon calcium imaging from the primary visual cortex (V1) of awake mice, we discovered that a flash of sinusoidal grating per se induces an early, transient activation as well as a long-delayed reactivation in V1 neurons. This late response, which started hundreds of milliseconds after the flash and persisted for approximately 2 s, was also observed in human V1 electroencephalogram. When another drifting grating stimulus arrived during the late response, the V1 neurons exhibited a sublinear, but apparently increased response, especially to the same grating orientation. In behavioral tests of mice and humans, the flashing stimulation enhanced the detection power of the identically orientated visual stimulation only when the second stimulation was presented during the time window of the late response. Therefore, V1 late responses likely provide a neural basis for admixing temporally separated stimuli and extracting identical features in time-varying visual environments. PMID:26274866

New Insights into the Explosion Source from SPE

NASA Astrophysics Data System (ADS)

Patton, H. J.

2015-12-01

Phase I of the Source Physics Experiments (SPE) is a series of chemical explosions at varying depths and yields detonated in the same emplacement hole on Climax stock, a granitic pluton located on the Nevada National Security Site. To date, four of the seven planned tests have been conducted, the last in May 2015, called SPE-4P, with a scaled depth of burial of 1549 m/kt1/3 in order to localize the source in time and space. Surface ground motions validated that the source medium did not undergo spallation, and a key experimental objective was achieved where SPE-4P is the closest of all tests in the series to a pure monopole source and will serve as an empirical Green's function for analysis against other SPE tests. A scientific objective of SPE is to understand mechanisms of rock damage for generating seismic waves, particularly surface and S waves, including prompt damage under compressive stresses and "late-time" damage under tensile stresses. Studies have shown that prompt damage can explain ~75% of the seismic moment for some SPE tests. Spallation is a form of late-time damage and a facilitator of damage mechanisms under tensile stresses including inelastic brittle deformation and shear dilatancy on pre-existing faults or joints. As an empirical Green's function, SPE-4P allows the study of late-time damage mechanisms on other SPE tests that induce spallation and late-time damage, and I'll discuss these studies. The importance for nuclear monitoring cannot be overstated because new research shows that damage mechanisms can affect surface wave magnitude Ms more than tectonic release, and are a likely factor related to anomalous mb-Ms behavior for North Korean tests.

The dynamics of evolving beliefs, concerns emotions, and behavioral avoidance following 9/11: a longitudinal analysis of representative archival samples.

PubMed

McArdle, Shelly C; Rosoff, Heather; John, Richard S

2012-04-01

September 11 created a natural experiment that enables us to track the psychological effects of a large-scale terror event over time. The archival data came from 8,070 participants of 10 ABC and CBS News polls collected from September 2001 until September 2006. Six questions investigated emotional, behavioral, and cognitive responses to the events of September 11 over a five-year period. We found that heightened responses after September 11 dissipated and reached a plateau at various points in time over a five-year period. We also found that emotional, cognitive, and behavioral reactions were moderated by age, sex, political affiliation, and proximity to the attack. Both emotional and behavioral responses returned to a normal state after one year, whereas cognitively-based perceptions of risk were still diminishing as late as September 2006. These results provide insight into how individuals will perceive and respond to future similar attacks. © 2012 Society for Risk Analysis.

Appointment-keeping behavior of Medicaid-enrolled pediatric dental patients in eastern Iowa.

PubMed

Iben, P; Kanellis, M J; Warren, J

2000-01-01

The purpose of this prospective study was to assess the appointment-keeping behavior of Medicaid-enrolled pediatric dental patients in three Eastern Iowa practices. During the month of October 1998, a tally was kept of all patient appointments at a private pediatric dental office, a public health dental clinic, and a university-based pediatric dentistry clinic. Patients were categorized as either Medicaid or non-Medicaid. Appointment behavior categories were defined as: On time; Failure; Late-notice Cancellation (less than 24 hours notice); and Tardy (greater than 10 minutes). The data was entered in SPSS and analyzed using the chi square statistic. Statistical significance was P < 0.05. A total of 1,406 appointments were recorded for all three sites. Overall, patients on Iowa Medicaid had higher appointment failure, late-notice cancellation, and tardiness rates than non-Medicaid patients at all three clinics. However, these differences were only statistically significant for the private office and the university-based clinic. Failed appointment rates for Medicaid patients were much higher at the private office (38%) than at the other two sites. Consistent with anecdotal reports from dentists, Medicaid patients had higher rates of broken appointments than did non-Medicaid patients, particularly in a private practice setting.

Figure-ground activity in primary visual cortex (V1) of the monkey matches the speed of behavioral response.

PubMed

Supèr, Hans; Spekreijse, Henk; Lamme, Victor A F

2003-06-26

To look at an object its position in the visual scene has to be localized and subsequently appropriate oculo-motor behavior needs to be initiated. This kind of behavior is largely controlled by the cortical executive system, such as the frontal eye field. In this report, we analyzed neural activity in the visual cortex in relation to oculo-motor behavior. We show that in a figure-ground detection task, the strength of late modulated activity in the primary visual cortex correlates with the saccade latency. We propose that this may indicate that the variability of reaction times in the detection of a visual stimulus is reflected in low-level visual areas as well as in high-level areas.

Does Parental Divorce Increase Risk Behaviors among 15/16 and 18/19 year-old Adolescents? A Study from Oslo, Norway.

PubMed

Zeratsion, Henok; Bjertness, Cecilie B; Lien, Lars; Haavet, Ole R; Dalsklev, Madeleine; Halvorsen, Jon A; Bjertness, Espen; Claussen, Bjørgulf

2014-01-01

Several studies have reported an increase in risk behaviors among adolescents after experience of parental divorce. The aim of the study was to investigate whether parental divorce is associated with risk behavior among adolescents independent of mental health problems, first when early divorce was experienced, and second after experience of late parental divorce. One prospective (n=1861) and one cross-sectional study (n=2422) were conducted using data from two Young-HUBRO surveys in Oslo, Norway. All 15/16 year-old 10(th) grade students who participated in the first survey in the school year 2000/01 were followed-up in 2004 when they were 18/19 year-olds. The follow-up rate was 68%. The prospective study investigated the influence of late parental divorce that occurred between the age of 15/16 and 18/19. In the cross-sectional study we focused on early parental divorce that occurred before the participants were 15/16 year-old. In the prospective study we could not discern a significant association between experiencing late parental divorce and an increase in risk behaviors among 18/19 year-old adolescents. In the cross-sectional study parental divorce was significantly associated with cigarette smoking and using doping agents. Parental divorce that occurs when the children of divorced parents are 15/16 year-old or younger is associated with an increase in cigarette smoking and use of doping agents. However, no evidence of significant association is found between experience of late parental divorce and risk behaviors in late adolescence.

Does Parental Divorce Increase Risk Behaviors among 15/16 and 18/19 year-old Adolescents? A Study from Oslo, Norway

PubMed Central

Zeratsion, Henok; Bjertness, Cecilie B; Lien, Lars; Haavet, Ole R; Dalsklev, Madeleine; Halvorsen, Jon A; Bjertness, Espen; Claussen, Bjørgulf

2014-01-01

Background: Several studies have reported an increase in risk behaviors among adolescents after experience of parental divorce. The aim of the study was to investigate whether parental divorce is associated with risk behavior among adolescents independent of mental health problems, first when early divorce was experienced, and second after experience of late parental divorce. Method: One prospective (n=1861) and one cross-sectional study (n=2422) were conducted using data from two Young-HUBRO surveys in Oslo, Norway. All 15/16 year-old 10th grade students who participated in the first survey in the school year 2000/01 were followed-up in 2004 when they were 18/19 year-olds. The follow-up rate was 68%. The prospective study investigated the influence of late parental divorce that occurred between the age of 15/16 and 18/19. In the cross-sectional study we focused on early parental divorce that occurred before the participants were 15/16 year-old. Results:In the prospective study we could not discern a significant association between experiencing late parental divorce and an increase in risk behaviors among 18/19 year-old adolescents. In the cross-sectional study parental divorce was significantly associated with cigarette smoking and using doping agents. Conclusion: Parental divorce that occurs when the children of divorced parents are 15/16 year-old or younger is associated with an increase in cigarette smoking and use of doping agents. However, no evidence of significant association is found between experience of late parental divorce and risk behaviors in late adolescence. PMID:25006342

Prevalence of Bulimic Behaviors and Trends in Eating Attitudes among Turkish Late Adolescents

ERIC Educational Resources Information Center

Kiziltan, Gul; Karabudak, Efsun; Unver, Sibel; Sezgin, Emine; Unal, Ayse

2006-01-01

The eating attitudes and the prevalence of bulimic behaviors in a group of 300 late adolescents were investigated using the key questions from the Bulimia Investigatory Test, Edinburgh (BITE), and additional questions. Only four subjects (1.3%) scored above the cut-off point on the BITE, and prevalence rates of males and females were the same.…

Developmental Trajectories of Children's Behavioral Engagement in Late Elementary School: Both Teachers and Peers Matter

ERIC Educational Resources Information Center

De Laet, Steven; Colpin, Hilde; Vervoort, Eleonora; Doumen, Sarah; Van Leeuwen, Karla; Goossens, Luc; Verschueren, Karine

2015-01-01

The present longitudinal study examined how relationships with teachers and peers jointly shape the development of children's behavioral engagement in late elementary school. A sample of 586 children (46% boys; M[subscript age] = 9.26 years at Wave 1) was followed throughout Grades 4, 5, and 6. A multidimensional approach was adopted,…

Parenting, Peer Orientation, Drug Use, and Antisocial Behavior in Late Adolescence: A Cross-National Study

ERIC Educational Resources Information Center

Claes, Michel; Lacourse, Eric; Ercolani, Anna-Paula; Pierro, Antonio; Leone, Luigi; Presaghi, Fabio

2005-01-01

The objective of this study was to investigate the links between maternal and paternal bonding, parental practices, orientation toward peers, and the prevalence of drug use and antisocial behavior during late adolescence. A model was tested using structural equation modeling in order to verify the robustness of the investigated links across 3…

Acquisition of neural learning in cerebellum and cerebral cortex for smooth pursuit eye movements

PubMed Central

Li, Jennifer X.; Medina, Javier F.; Frank, Loren M.; Lisberger, Stephen G.

2011-01-01

We have evaluated the emergence of neural learning in the frontal eye fields (FEFSEM) and the floccular complex of the cerebellum while monkeys learned a precisely-timed change in the direction of pursuit eye movement. For each neuron, we measured the time course of changes in neural response across a learning session that comprised at least 100 repetitions of an instructive change in target direction. In both areas, the average population learning curves tracked the behavioral changes with high fidelity, consistent with possible roles in driving learning. However, the learning curves of individual neurons sometimes bore little relation to the smooth, monotonic progression of behavioral learning. In the FEFSEM, neural learning was episodic. For individual neurons, learning appeared at different times during the learning session and sometimes disappeared by the end of the session. Different FEFSEM neurons expressed maximal learning at different times relative to the acquisition of behavioral learning. In the floccular complex, many Purkinje cells acquired learned simple-spike responses according to the same time course as behavioral learning and retained their learned responses throughout the learning session. A minority of Purkinje cells acquired learned responses late in the learning session, after behavioral learning had reached an asymptote. We conclude that learning in single neurons can follow a very different time course from behavioral learning. Both the FEFSEM and the floccular complex contain representations of multiple temporal components of learning, with different neurons contributing to learning at different times during the acquisition of a learned movement. PMID:21900551

The risks for late adolescence of early adolescent marijuana use.

PubMed Central

Brook, J S; Balka, E B; Whiteman, M

1999-01-01

OBJECTIVES: The purpose of this study was to assess the relation of early adolescent marijuana use to late adolescent problem behaviors, drug-related attitudes, drug problems, and sibling and peer problem behavior. METHODS: African American (n = 627) and Puerto Rican (n = 555) youths completed questionnaires in their classrooms initially and were individually interviewed 5 years later. Logistic regression analysis estimated increases in the risk of behaviors or attitudes in late adolescence associated with more frequent marijuana use in early adolescence. RESULTS: Early adolescent marijuana use increased the risk in late adolescence of not graduating from high school; delinquency; having multiple sexual partners; not always using condoms; perceiving drugs as not harmful; having problems with cigarettes, alcohol, and marijuana; and having more friends who exhibit deviant behavior. These relations were maintained with controls for age, sex, ethnicity, and, when available, earlier psychosocial measures. CONCLUSIONS: Early adolescent marijuana use is related to later adolescent problems that limit the acquisition of skills necessary for employment and heighten the risks of contracting HIV and abusing legal and illegal substances. Hence, assessments of and treatments for adolescent marijuana use need to be incorporated in clinical practice. PMID:10511838

Assessing Peer Conflict and Aggressive Behaviors: A Guide for Out-of-School Time Program Practitioners. Research-to-Results Brief. Publication #2009-43

ERIC Educational Resources Information Center

Sidorowicz, Kathleen; Hair, Elizabeth C.

2009-01-01

Peer relations during middle childhood and adolescence are an important part of children's social and emotional development. Children and adolescents pick up essential social and communication skills from their peers as they move into late adolescence and early adulthood. Peer conflict is not necessarily a bad thing; disagreement and conflict are…

Universality of fast quenches from the conformal perturbation theory

NASA Astrophysics Data System (ADS)

Dymarsky, Anatoly; Smolkin, Michael

2018-01-01

We consider global quantum quenches, a protocol when a continuous field theoretic system in the ground state is driven by a homogeneous time-dependent external interaction. When the typical inverse time scale of the interaction is much larger than all relevant scales except for the UV-cutoff the system's response exhibits universal scaling behavior. We provide both qualitative and quantitative explanations of this universality and argue that physics of the response during and shortly after the quench is governed by the conformal perturbation theory around the UV fixed point. We proceed to calculate the response of one and two-point correlation functions confirming and generalizing universal scalings found previously. Finally, we discuss late time behavior after the quench and argue that all local quantities will equilibrate to their thermal values specified by an excess energy acquired by the system during the quench.

Post-retrieval extinction in adolescence prevents return of juvenile fear

PubMed Central

Jones, Carolyn E.

2016-01-01

Traumatic experiences early in life can contribute to the development of mood and anxiety disorders that manifest during adolescence and young adulthood. In young rats exposed to acute fear or stress, alterations in neural development can lead to enduring behavioral abnormalities. Here, we used a modified extinction intervention (retrieval+extinction) during late adolescence (post-natal day 45 [p45]), in rats, to target auditory Pavlovian fear associations acquired as juveniles (p17 and p25). The effects of adolescent intervention were examined by assessing freezing as adults during both fear reacquisition and social transmission of fear from a cagemate. Rats underwent testing or training at three time points across development: juvenile (p17 or p25), adolescent (p45), and adult (p100). Retrieval+extinction during late adolescence prevented social reinstatement and recovery over time of fears initially acquired as juveniles (p17 and p25, respectively). Adolescence was the only time point tested here where retrieval+extinction prevented fear recall of associations acquired 20+ days earlier. PMID:27634147

Early adolescence behavior problems and timing of poverty during childhood: A comparison of lifecourse models.

PubMed

Mazza, Julia Rachel S E; Lambert, Jean; Zunzunegui, Maria Victoria; Tremblay, Richard E; Boivin, Michel; Côté, Sylvana M

2017-03-01

Poverty is a well-established risk factor for the development of behavior problems, yet little is known about how timing of exposure to childhood poverty relates to behavior problems in early adolescence. To examine the differential effects of the timing of poverty between birth and late childhood on behavior problems in early adolescence by modeling lifecourse models, corresponding to sensitive periods, accumulation of risk and social mobility models. We used the Quebec Longitudinal Study of Child Development (N = 2120). Poverty was defined as living below the low-income thresholds defined by Statistics Canada and grouped into three time periods: between ages 0-3 years, 5-7 years, and 8-12 years. Main outcomes were teacher's report of hyperactivity, opposition and physical aggression at age 13 years. Structured linear regression analyses were conducted to estimate the contribution of poverty during the three selected time periods to behavior problems. Partial F-tests were used to compare nested lifecourse models to a full saturated model (all poverty main effects and possible interactions). Families who experienced poverty at all time periods were 9.3% of the original sample. Those who were poor at least one time period were 39.2%. The accumulation of risk model was the best fitting model for hyperactivity and opposition. The risk for physical aggression problems was associated only to poverty between 0 and 3 years supporting the sensitive period. Early and prolonged exposure to childhood poverty predicted higher levels of behavior problems in early adolescence. Antipoverty policies targeting the first years of life and long term support to pregnant women living in poverty are likely to reduce behavior problems in early adolescence. Copyright © 2017 Elsevier Ltd. All rights reserved.

Ghost Dark Energy with Sign-changeable Interaction Term

NASA Astrophysics Data System (ADS)

Zadeh, M. Abdollahi; Sheykhi, A.; Moradpour, H.

2017-11-01

Regarding the Veneziano ghost of QCD and its generalized form, we consider a Friedmann-Robertson-Walker (FRW) universe filled by a pressureless matter and a dark energy component interacting with each other through a mutual sign-changeable interaction of positive coupling constant. Our study shows that, at the late time, for the deceleration parameter we have q → -1, while the equation of state parameter of the interacting ghost dark energy (GDE) does not cross the phantom line, namely ω D ≥ -1. We also extend our study to the generalized ghost dark energy (GGDE) model and show that, at late time, the equation of state parameter of the interacting GGDE also respects the phantom line in both flat and non-flat universes. Moreover, we find out that, unlike the non-flat universe, we have q → -1 at late time for flat FRW universe. In order to make the behavior of the underlying models more clear, the deceleration parameter q as well as the equation of state parameter w D for flat and closed universes have been plotted against the redshift parameter, z. All of the studied cases admit a transition in the expansion history of universe from a deceleration phase to an accelerated one around z ≈ 0.6.

Experimental tests of truncated diffusion in fault damage zones

NASA Astrophysics Data System (ADS)

Suzuki, Anna; Hashida, Toshiyuki; Li, Kewen; Horne, Roland N.

2016-11-01

Fault zones affect the flow paths of fluids in groundwater aquifers and geological reservoirs. Fault-related fracture damage decreases to background levels with increasing distance from the fault core according to a power law. This study investigated mass transport in such a fault-related structure using nonlocal models. A column flow experiment is conducted to create a permeability distribution that varies with distance from a main conduit. The experimental tracer response curve is preasymptotic and implies subdiffusive transport, which is slower than the normal Fickian diffusion. If the surrounding area is a finite domain, an upper truncated behavior in tracer response (i.e., exponential decline at late times) is observed. The tempered anomalous diffusion (TAD) model captures the transition from subdiffusive to Fickian transport, which is characterized by a smooth transition from power-law to an exponential decline in the late-time breakthrough curves.

Behavioral phenomenology in Alzheimer's disease, frontotemporal dementia, and late-life depression: a retrospective analysis.

PubMed

Swartz, J R; Miller, B L; Lesser, I M; Booth, R; Darby, A; Wohl, M; Benson, D F

1997-04-01

Often patients in the early stages of Alzheimer's disease (AD), frontotemporal dementia (FTD), and late-life depression can be difficult to differentiate clinically. Although subtle cognitive distinctions exist between these disorders, noncognitive behavioral phenomenology may provide additional discriminating power. In 19 subjects with AD, 19 with FTD, 16 with late-life psychotic depression (LLPD), and 19 with late-life nonpsychotic depression (LLNPD), noncognitive behavioral symptoms were quantified retrospectively using the Schedules for Clinical Assessment in Neuropsychiatry (SCAN) and compared using both a one-way ANOVA and a multivariate stepwise discriminant analysis, which utilized a jackknife procedure. The FTD group showed the highest mean total SCAN score, while the AD group showed the lowest. ANOVA showed significant differences in the mean total SCAN scores between the four diagnostic groups (P < .0001). With the discriminant analysis, the four disorders demonstrated different clusters of behavioral abnormalities and were differentiated by these symptoms (P < .0001). A subset of 14 SCAN item group symptoms was identified that collectively classified the following percentages of subjects in each diagnostic category: AD 94.7%, FTD 100%, LLPD 87.5%, and LLNPD 100%. These results indicate that AD, FTD, LLPD, and LLNPD were distinguished retrospectively by the SCAN without using cognitive data. Better definition of the longitudinal course of noncognitive behavioral symptoms in different dementias and psychiatric disorders will be valuable both for diagnosis and to help define behavioral syndromes that are associated with selective neuroanatomic and neurochemical brain pathology.

Alcohol Use and Related Behaviors among Late-Adolescent Urban Youths: Peer and Parent Influences

ERIC Educational Resources Information Center

Schwinn, Traci M.; Schinke, Steven P.

2014-01-01

Peer and parent influences on alcohol use and related risky behaviors were examined in a sample of late-adolescent (M = 17.3 years; SD = 1.11 years) urban youths. Participants (N = 400) completed an online measure assessing peer influences of alcohol use and alcohol offers and also parental influences of rules against alcohol use and perceived…

Experimental Modelling of the Consequences of Brief Late Gestation Asphyxia on Newborn Lamb Behaviour and Brain Structure

PubMed Central

Yawno, Tamara; Witjaksono, Anissa; Miller, Suzie L.; Walker, David W.

2013-01-01

Brief but severe asphyxia in late gestation or at the time of birth may lead to neonatal hypoxic ischemic encephalopathy and is associated with long-term neurodevelopmental impairment. We undertook this study to examine the consequences of transient in utero asphyxia in late gestation fetal sheep, on the newborn lamb after birth. Surgery was undertaken at 125 days gestation for implantation of fetal catheters and placement of a silastic cuff around the umbilical cord. At 132 days gestation (0.89 term), the cuff was inflated to induce umbilical cord occlusion (UCO), or sham (control). Fetal arterial blood samples were collected for assessment of fetal wellbeing and the pregnancy continued until birth. At birth, behavioral milestones for newborn lambs were recorded over 24 h, after which the lambs were euthanased for brain collection and histopathology assessments. After birth, UCO lambs displayed significant latencies to (i) use all four legs, (ii) attain a standing position, (iii) find the udder, and (iv) successfully suckle - compared to control lambs. Brains of UCO lambs showed widespread pathologies including cell death, white matter disruption, intra-parenchymal hemorrhage and inflammation, which were not observed in full term control brains. UCO resulted in some preterm births, but comparison with age-matched preterm non-UCO control lambs showed that prematurity per se was not responsible for the behavioral delays and brain structural abnormalities resulting from the in utero asphyxia. These results demonstrate that a single, brief fetal asphyxic episode in late gestation results in significant grey and white matter disruption in the developing brain, and causes significant behavioral delay in newborn lambs. These data are consistent with clinical observations that antenatal asphyxia is causal in the development of neonatal encephalopathy and provide an experimental model to advance our understanding of neuroprotective therapies. PMID:24223120

On Early Starters and Late Bloomers: The Development of Sexual Behavior in Adolescence Across Personality Types

PubMed Central

Overbeek, Geertjan; Dubas, Judith Semon; van Aken, Marcel A. G.

2013-01-01

Little is known about the relationship between personality and sexual development among mid-adolescents. In the current study, we used a person-centered approach to investigate the relation between personality types and the development of sexual behavior. We hypothesized that undercontrolling adolescents would engage in more advanced, casual, and risky sexual behavior compared to their resilient and overcontrolling peers. Data were used from 407 mid-adolescents (Mage = 14.5) followed across four measurement waves spanning 18 months. Results from latent class analyses (LCA) identified the three classical personality types: resilients, undercontrollers, and overcontrollers. Controlling for perceived pubertal timing and biological sex, latent growth curve analyses in Mplus showed that, at baseline, undercontrollers were more sexually experienced and engaged in more casual and risky sexual behavior than resilients and overcontrollers. Although initial levels of sexual behavior differed by personality types, over time increases in sexual behavior occurred at a similar rate across the types. Overall, the current study showed that undercontrolling adolescents are early sexual developers who engage in more advanced, casual, and risky sexual behavior than other adolescents. The implications of these findings for longer-term differences in sexual behavior between personality types in later adolescence are discussed. PMID:24007372

Late-instar Behavior of Aedes aegypti (Diptera: Culicidae) Larvae in Different Thermal and Nutritive Environments.

PubMed

Reiskind, Michael H; Janairo, M Shawn

2015-09-01

The effects of temperature on ectotherm growth have been well documented. How temperature affects foraging behavior is less well explored, and has not been studied in larval mosquitoes. We hypothesized that temperature changes foraging behavior in the aquatic larval phase of the mosquito, Aedes aegypti L. Based on empirical results in other systems, we predicted that foraging effort would increase at higher temperatures in these insects. We tested this prediction over three temperature conditions at two food levels. We measured behaviors by video recording replicated cohorts of fourth-instar mosquitoes and assessing individual behavior and time budgets using an ethogram. We found both food level and temperature had significant impacts on larval foraging behavior, with more time spent actively foraging at low food levels and at low temperatures, and more occurrences of active foraging at both temperature extremes. These results are contrary to some of our predictions, but fit into theoretical responses to temperature based upon dynamic energy budget models. © The Authors 2015. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Longitudinal pathways from unconventional personal attributes in the late 20s to cannabis use prior to sexual intercourse in the late 30s.

PubMed

Lee, Jung Yeon; Brook, Judith S; Pahl, Kerstin; Brook, David W

2017-11-01

A quarter of people living with human immunodeficiency virus (HIV) infection in the United States are women. Furthermore, African American and Hispanic/Latina women continue to be disproportionately affected by HIV, compared with women of other races/ethnicities. Cannabis use prior to intercourse may be associated with increased risky sexual behaviors which are highly related to HIV. The ultimate goal of this research is to better understand the relationships between unconventional personal attributes (e.g., risk-taking behaviors) in the late 20s, substance use (e.g., alcohol) in the mid 30s, and cannabis use prior to intercourse in the late 30s using a community sample; such an understanding may inform interventions. This study employing data from the Harlem Longitudinal Development Study includes 343 female participants (50% African Americans, 50% Puerto Ricans). Structural equation modeling indicated that unconventional personal attributes in the late 20s were associated with substance use in the mid 30s (β=0.32, p<0.001), which in turn, was associated with cannabis use prior to sexual intercourse in the late 30s (β=0.64, p<0.001). Unconventional personal attributes in the late 20s were also directly related to cannabis use prior to sexual intercourse in the late 30s (β=0.39, p<0.01). The findings of this study suggest that interventions focused on decreasing unconventional personal attributes as well as substance use may reduce sexual risk behaviors among urban African American and Puerto Rican women. Also, the implications of this study for health care providers and researchers working in HIV prevention are that these precursors may be useful as patient screening tools. Copyright © 2017 Elsevier Ltd. All rights reserved.

Development of an attachment-informed measure of sexual behavior in late adolescence.

PubMed

Szielasko, Alicia L; Symons, Douglas K; Lisa Price, E

2013-04-01

There is considerable interest in relations between sexual behavior and romantic attachment styles in adolescence as attachment needs are increasingly met through intimate partners rather than parents. The objectives of this research were to organize a measure of sexual behavior within an attachment theory framework, and then show that this new measure uniquely predicted sexual approach styles and invasive sexual experiences. 190 18- and 19-year-old university students in late adolescence completed sexual behavior items that were provided ambivalent (anxious) and avoidant dimensions. These were systematically related to the romantic attachment dimensions of the Experiences in Close Relationships - Revised. However, even after romantic relationship style, gender, and social desirability were controlled, avoidance in sexual relationships predicted lifetime sexual partner number and negatively predicted positive sexual strategies, and ambivalence in sexual relationships predicted invasive and coercive sexual behaviors. A measure specific to sexual relationships informs the attachment and romantic context of sex in late adolescence. Copyright © 2013 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

Cannibalism in Tyrannosaurus rex.

PubMed

Longrich, Nicholas R; Horner, John R; Erickson, Gregory M; Currie, Philip J

2010-10-15

Tyrannosaurus rex was one of the largest terrestrial carnivores of all time, and consequently its ecology and diet have been the focus of much discussion. However, there is little direct evidence of diet or feeding habits in this species. Examination of museum collections has revealed four specimens of Tyrannosaurus rex that bear tooth marks made by large, carnivorous dinosaurs. Because Tyrannosaurus is the only large carnivore known from the Late Maastrichtian of western North America, we infer that Tyrannosaurus made these tooth marks. The marks are interpreted as feeding traces and these fossils therefore record instances of cannibalism. Given that this behavior has a low preservation potential, cannibalism seems to have been a surprisingly common behavior in Tyrannosaurus, and this behavior may have been relatively common in carnivorous dinosaurs.

Differential risk for late adolescent conduct problems and mood dysregulation among children with early externalizing behavior problems.

PubMed

Okado, Yuko; Bierman, Karen L

2015-05-01

To investigate the differential emergence of antisocial behaviors and mood dysregulation among children with externalizing problems, the present study prospectively followed 317 high-risk children with early externalizing problems from school entry (ages 5-7) to late adolescence (ages 17-19). Latent class analysis conducted on their conduct and mood symptoms in late adolescence revealed three distinct patterns of symptoms, characterized by: 1) criminal offenses, conduct disorder symptoms, and elevated anger ("conduct problems"), 2) elevated anger, dysphoric mood, and suicidal ideation ("mood dysregulation"), and 3) low levels of severe conduct and mood symptoms. A diathesis-stress model predicting the first two outcomes was tested. Elevated overt aggression at school entry uniquely predicted conduct problems in late adolescence, whereas elevated emotion dysregulation at school entry uniquely predicted mood dysregulation in late adolescence. Experiences of low parental warmth and peer rejection in middle childhood moderated the link between early emotion dysregulation and later mood dysregulation but did not moderate the link between early overt aggression and later conduct problems. Thus, among children with early externalizing behavior problems, increased risk for later antisocial behavior or mood dysfunction may be identifiable in early childhood based on levels of overt aggression and emotion dysregulation. For children with early emotion dysregulation, however, increased risk for mood dysregulation characterized by anger, dysphoric mood, and suicidality--possibly indicative of disruptive mood dysregulation disorder--emerges only in the presence of low parental warmth and/or peer rejection during middle childhood.

On information loss in AdS 3/CFT 2

DOE PAGES

Fitzpatrick, A. Liam; Kaplan, Jared; Li, Daliang; ...

2016-05-18

We discuss information loss from black hole physics in AdS 3, focusing on two sharp signatures infecting CFT 2 correlators at large central charge c: ‘forbidden singularities’ arising from Euclidean-time periodicity due to the effective Hawking temperature, and late-time exponential decay in the Lorentzian region. We study an infinite class of examples where forbidden singularities can be resolved by non-perturbative effects at finite c, and we show that the resolution has certain universal features that also apply in the general case. Analytically continuing to the Lorentzian regime, we find that the non-perturbative effects that resolve forbidden singularities qualitatively change themore » behavior of correlators at times t ~S BH, the black hole entropy. This may resolve the exponential decay of correlators at late times in black hole backgrounds. By Borel resumming the 1/c expansion of exact examples, we explicitly identify ‘information-restoring’ effects from heavy states that should correspond to classical solutions in AdS 3. Lastly, our results suggest a line of inquiry towards a more precise formulation of the gravitational path integral in AdS 3.« less

Brain Activity during Methamphetamine Anticipation in a Non-Invasive Self-Administration Paradigm in Mice.

PubMed

Juárez-Portilla, Claudia; Pitter, Michael; Kim, Rachel D; Patel, Pooja Y; Ledesma, Robert A; LeSauter, Joseph; Silver, Rae

2018-01-01

The ability to sense time and anticipate events is critical for survival. Learned responses that allow anticipation of the availability of food or water have been intensively studied. While anticipatory behaviors also occur prior to availability of regularly available rewards, there has been relatively little work on anticipation of drugs of abuse, specifically methamphetamine (MA). In the present study, we used a protocol that avoided possible CNS effects of stresses of handling or surgery by testing anticipation of MA availability in animals living in their home cages, with daily voluntary access to the drug at a fixed time of day. Anticipation was operationalized as the amount of wheel running prior to MA availability. Mice were divided into four groups given access to either nebulized MA or water, in early or late day. Animals with access to MA, but not water controls, showed anticipatory activity, with more anticipation in early compared to late day and significant interaction effects. Next, we explored the neural basis of the MA anticipation, using c-FOS expression, in animals euthanized at the usual time of nebulization access. In the dorsomedial hypothalamus (DMH) and orbitofrontal cortex (OFC), the pattern of c-FOS expression paralleled that of anticipatory behavior, with significant main and interaction effects of treatment and time of day. The results for the lateral septum (LS) were significant for main effects and marginally significant for interaction effects. These studies suggest that anticipation of MA is associated with activation of brain regions important in circadian timing, emotional regulation, and decision making.

Brain Activity during Methamphetamine Anticipation in a Non-Invasive Self-Administration Paradigm in Mice

PubMed Central

Pitter, Michael; Patel, Pooja Y.; Ledesma, Robert A.

2018-01-01

The ability to sense time and anticipate events is critical for survival. Learned responses that allow anticipation of the availability of food or water have been intensively studied. While anticipatory behaviors also occur prior to availability of regularly available rewards, there has been relatively little work on anticipation of drugs of abuse, specifically methamphetamine (MA). In the present study, we used a protocol that avoided possible CNS effects of stresses of handling or surgery by testing anticipation of MA availability in animals living in their home cages, with daily voluntary access to the drug at a fixed time of day. Anticipation was operationalized as the amount of wheel running prior to MA availability. Mice were divided into four groups given access to either nebulized MA or water, in early or late day. Animals with access to MA, but not water controls, showed anticipatory activity, with more anticipation in early compared to late day and significant interaction effects. Next, we explored the neural basis of the MA anticipation, using c-FOS expression, in animals euthanized at the usual time of nebulization access. In the dorsomedial hypothalamus (DMH) and orbitofrontal cortex (OFC), the pattern of c-FOS expression paralleled that of anticipatory behavior, with significant main and interaction effects of treatment and time of day. The results for the lateral septum (LS) were significant for main effects and marginally significant for interaction effects. These studies suggest that anticipation of MA is associated with activation of brain regions important in circadian timing, emotional regulation, and decision making. PMID:29632871

Improving medication adherence with a targeted, technology-driven disease management intervention.

PubMed

Lawrence, David B; Allison, Wanda; Chen, Joyce C; Demand, Michael

2008-06-01

Treatment adherence is critical in managing chronic disease, but achieving it remains an elusive goal across many prevalent conditions. As part of its care management strategy, BlueCross BlueShield of South Carolina (BCBSSC) implemented the Longitudinal Adherence Treatment Evaluation program, a behavioral intervention to improve medication adherence among members with cardiovascular disease and/or diabetes. The objectives of this study were to 1) assess the effectiveness of telephonic intervention in influencing reinitiation of medication therapy, and 2) evaluate the rate and timing of medication reinitiation. BCBSSC applied algorithms against pharmacy claims data to identify patients prescribed targeted medications who were 60 or more days overdue for refills. This information was provided to care managers to address during their next patient contact. Care managers received focused training on techniques for medication behavior change, readiness to change, motivational interviewing, and active listening. Training also addressed common barriers to adherence and available resources, including side effect management, mail order benefits, drug assistance programs, medication organizers, and reminder systems. Overdue refills were tracked for 12 months, with medication reinitiation followed for an additional 3 months. In the intervention group, 94 patients were identified with 123 instances of late medication refills. In the age- and gender-matched comparison group, 61 patients were identified with 76 late refills. The intervention group had a significantly higher rate of medication reinitiation (59.3%) than the control group (42.1%; P < 0.05). Time to reinitiation was significantly shorter in the intervention group, 59.5 (+/- 69.0) days vs. 107.4 (+/- 109) days for the control group (P < 0.05). This initiative demonstrated that a targeted disease management intervention promoting patient behavior change increased the number of patients who reinitiated therapy after a period of nonadherence and decreased the time from nonadherence to adherence.

Long-term effects of early adolescent methamphetamine exposure on depression-like behavior and the hypothalamic vasopressin system in mice.

PubMed

Joca, Lauren; Zuloaga, Damian G; Raber, Jacob; Siegel, Jessica A

2014-01-01

Methamphetamine (MA) has neurotoxic effects on the adult human brain that can lead to deficits in behavior and cognition. However, relatively little research has examined the behavioral or neurotoxic effects of MA in adolescents. The rising rates of adolescent MA use make it imperative that we understand the long-term effects of MA exposure on the adolescent brain and how these effects may differ from those seen in adults. In this study, the long-term effects of MA exposure during early adolescence on behavior and the vasopressin system in the paraventricular nucleus of the hypothalamus in late adolescent and adult male and female C57BL/6J mice were examined. MA exposure increased depression-like behavior in the Porsolt forced swim test in both late adolescent and adult male and female mice. Late adolescent male mice exposed to MA also showed a decrease in the number of vasopressin-immunoreactive neurons in the paraventricular nucleus compared to sex-matched saline-treated controls. Thus, similar to humans exposed to MA during adolescence, mice exposed to MA during adolescence show increased depression-like behavior later in life. These changes in behavior may be related to MA-induced alterations in vasopressin and the hypothalamic-pituitary-adrenal axis, especially in males. 2014 S. Karger AG, Basel

Later Start, Longer Sleep: Implications of Middle School Start Times.

PubMed

Temkin, Deborah A; Princiotta, Daniel; Ryberg, Renee; Lewin, Daniel S

2018-05-01

Although adolescents generally get less than the recommended 9 hours of sleep per night, research and effort to delay school start times have generally focused on high schools. This study assesses the relation between school start times and sleep in middle school students while accounting for potentially confounding demographic variables. Seventh and eighth grade students attending 8 late starting schools (∼8:00 am, n = 630) and 3 early starting schools (∼7:23 am, n = 343) from a diverse suburban school district completed online surveys about their sleep behaviors. Doubly robust inverse probability of treatment weighted regression estimates of the effects of later school start time on student bedtimes, sleep duration, and daytime sleepiness were generated. Attending a school starting 37 minutes later was associated with an average of 17 additional minutes of sleep per weeknight, despite an average bedtime 15 minutes later. Students attending late starting schools were less sleepy than their counterparts in early starting schools, and more likely to be wide awake. Later school start times were significantly associated with improved sleep outcomes for early adolescents, providing support for the movement to delay school start times for middle schools. © 2018, American School Health Association.

Comparison of stream reach scale transport of rhodamine WT and NaCl in coupled mountain stream-hyporheic system

Treesearch

A. Bouchier; M. N. Gooseff; B. McGlynn; R. A. Payn; M. A. Briggs

2006-01-01

Rather than interpret the late-time behavior of rhodamine WT (RWT) breakthrough curves in stream tracer studies as indications of hyporheic exchanges we suggest that RWT is lost by sorption. We assessed the transport of RWT compared with NaCl during and after a 5 hour co-injection steady state drip experiment conducted in a headwater mountain stream. We hypothesize...

Climate and vegetational regime shifts in the late Paleozoic ice age earth.

PubMed

DiMichele, W A; Montañez, I P; Poulsen, C J; Tabor, N J

2009-03-01

The late Paleozoic earth experienced alternation between glacial and non-glacial climates at multiple temporal scales, accompanied by atmospheric CO2 fluctuations and global warming intervals, often attended by significant vegetational changes in equatorial latitudes of Pangaea. We assess the nature of climate-vegetation interaction during two time intervals: middle-late Pennsylvanian transition and Pennsylvanian-Permian transition, each marked by tropical warming and drying. In case study 1, there is a catastrophic intra-biomic reorganization of dominance and diversity in wetland, evergreen vegetation growing under humid climates. This represents a threshold-type change, possibly a regime shift to an alternative stable state. Case study 2 is an inter-biome dominance change in western and central Pangaea from humid wetland and seasonally dry to semi-arid vegetation. Shifts between these vegetation types had been occurring in Euramerican portions of the equatorial region throughout the late middle and late Pennsylvanian, the drier vegetation reaching persistent dominance by Early Permian. The oscillatory transition between humid and seasonally dry vegetation appears to demonstrate a threshold-like behavior but probably not repeated transitions between alternative stable states. Rather, changes in dominance in lowland equatorial regions were driven by long-term, repetitive climatic oscillations, occurring with increasing intensity, within overall shift to seasonal dryness through time. In neither case study are there clear biotic or abiotic warning signs of looming changes in vegetational composition or geographic distribution, nor is it clear that there are specific, absolute values or rates of environmental change in temperature, rainfall distribution and amount, or atmospheric composition, approach to which might indicate proximity to a terrestrial biotic-change threshold.

Sundowning: Late-Day Confusion

MedlinePlus

... behavior is unknown. Factors that may aggravate late-day confusion include: Fatigue Low lighting Increased shadows Disruption ... for activities and exposure to light during the day to encourage nighttime sleepiness. Limit daytime napping. Limit ...

Impact of Life History on Fear Memory and Extinction

PubMed Central

Remmes, Jasmin; Bodden, Carina; Richter, S. Helene; Lesting, Jörg; Sachser, Norbert; Pape, Hans-Christian; Seidenbecher, Thomas

2016-01-01

Behavioral profiles are strongly shaped by an individual's whole life experience. The accumulation of negative experiences over lifetime is thought to promote anxiety-like behavior in adulthood (“allostatic load hypothesis”). In contrast, the “mismatch hypothesis” of psychiatric disease suggests that high levels of anxiety-like behavior are the result of a discrepancy between early and late environment. The aim of the present study was to investigate how different life histories shape the expression of anxiety-like behavior and modulate fear memory. In addition, we aimed to clarify which of the two hypotheses can better explain the modulation of anxiety and fear. For this purpose, male mice grew up under either adverse or beneficial conditions during early phase of life. In adulthood they were further subdivided in groups that either matched or mismatched the condition experienced before, resulting in four different life histories. The main results were: (i) Early life benefit followed by late life adversity caused decreased levels of anxiety-like behavior. (ii) Accumulation of adversity throughout life history led to impaired fear extinction learning. Late life adversity as compared to late life benefit mainly affected extinction training, while early life adversity as compared to early life benefit interfered with extinction recall. Concerning anxiety-like behavior, the results do neither support the allostatic load nor the mismatch hypothesis, but rather indicate an anxiolytic effect of a mismatched early beneficial and later adverse life history. In contrast, fear memory was strongly affected by the accumulation of adverse experiences over the lifetime, therefore supporting allostatic load hypothesis. In summary, this study highlights that anxiety-like behavior and fear memory are differently affected by specific combinations of adverse or beneficial events experienced throughout life. PMID:27757077

Developmental changes in sleep biology and potential effects on adolescent behavior and caffeine use

PubMed Central

Carskadon, Mary A; Tarokh, Leila

2014-01-01

Adolescent development includes changes in the biological regulatory processes for the timing of sleep. Circadian rhythm changes and changes to the sleep-pressure system (sleep homeostasis) during adolescence both favor later timing of sleep. These changes, combined with prevailing social pressures, are responsible for most teens sleeping too late and too little; those who sleep least report consuming more caffeine. Although direct research findings are scarce, the likelihood of use and abuse of caffeine-laden products grows across the adolescent years due, in part, to excessive sleepiness. PMID:25293544

The Association Between Sleep Disordered Breathing, Academic Grades, and Cognitive and Behavioral Functioning Among Overweight Subjects During Middle to Late Childhood

PubMed Central

Beebe, Dean W.; Ris, M. Douglas; Kramer, Megan E.; Long, Elizabeth; Amin, Raouf

2010-01-01

Study Objectives: (1) to determine the associations of sleep disordered breathing (SDB) with behavioral functioning, cognitive test scores, and school grades during middle- to late-childhood, an under-researched developmental period in the SDB literature, and (2) to clarify whether associations between SDB and school grades are mediated by deficits in cognitive or behavioral functioning. Design: Cross-sectional correlative study. Setting: Office/hospital, plus reported functioning at home and at school. Participants: 163 overweight subjects aged 10-16.9 years were divided into 4 groups based upon their obstructive apnea+hypopnea index (AHI) during overnight polysomnography and parent report of snoring: Moderate-Severe OSA (AHI > 5, n = 42), Mild OSA (AHI = 1-5, n = 58), Snorers (AHI < 1 + snoring, n = 26), and No SDB (AHI < 1 and nonsnoring, n = 37). Measurements: Inpatient overnight polysomnography, parent- and self-report of school grades and sleep, parent- and teacher-report of daytime behaviors, and office-based neuropsychological testing. Results: The 4 groups significantly differed in academic grades and parent- and teacher-reported behaviors, particularly inattention and learning problems. These findings remained significant after adjusting for subject sex, race, socioeconomic status, and school night sleep duration. Associations with SDB were confined to reports of behavioral difficulties in real-world situations, and did not extend to office-based neuropsychological tests. Findings from secondary analyses were consistent with, but could not definitively confirm, a causal model in which SDB affects school grades via its impact on behavioral functioning. Conclusions: SDB during middle- to late-childhood is related to important aspects of behavioral functioning, especially inattention and learning difficulties, that may result in significant functional impairment at school. Citation: Beebe DW; Ris MD; Kramer ME; Long E; Amin R. The association between sleep disordered breathing, academic grades, and cognitive and behavioral functioning among overweight subjects during middle to late childhood. SLEEP 2010;33(11):1447-1456. PMID:21102986

Frontogenesis driven by horizontally quadratic distributions of density

NASA Technical Reports Server (NTRS)

Jacqmin, David

1991-01-01

Attention is given to the quadratic density distribution in a channel, which has been established by Simpson and Linden to be the simplest case of the horizontally nonlinear distribution of fluid density required for the production of frontogenesis. The porous-media and Boussinesq flow models are examined, and their evolution equations are reduced to one-dimensional systems. While both the porous-media and the inviscid/nondiffusive Boussinesq systems exhibit classic frontogenesis behavior, the viscous Boussinesq system exhibits a more complex behavior: boundary-layer effects force frontogenesis away from the lower boundary, and at late times the steepest density gradients are close to mid-channel.

Vaginal and Oral Sex Initiation Timing: A Focus on Gender and Race/Ethnicity.

PubMed

Holway, Giuseppina Valle

2015-07-01

Most previous studies on sexual initiation timing have examined its effects on a variety of subsequent outcomes without first examining the correlates and predictors of these timing categories. Studies that do exist often do not utilize samples through young adulthood, leading to a misclassified set of sexual timing categories. In addition, the literature does not adequately address the issues of oral sex timing. Therefore, the objectives of this study were 1) to explore age-cutoffs that mark the "normative" and "non-normative" entry into vaginal and oral sex among young women and men in the U.S., creating sexual four sexual initiation timing categories - "early," "normative," "late," and "inexperienced," and; 2) to examine the association between race/ethnicity and sexual initiation timing by gender. The National Longitudinal Study of Adolescent to Adult Health (Add Health) was used in both descriptive and multivariate contexts to determine the net association of gender and race/ethnicity with vaginal and oral sex initiation timing. Age-cutoffs for vaginal sex timing were similar for women and men, yet differed by gender for oral sex timing. Women were more likely than men to initiate vaginal sex (20% vs. 18%) and oral sex (19% vs. 16%) at an early age and less likely than men to initiate these behaviors at a late age (18% vs. 19% for vaginal sex, and 15% vs. 16% for oral sex). Although most respondents initiated these two behaviors by young adulthood, a considerable proportion remained inexperienced, with men more likely than women to report inexperience with vaginal sex (7% vs. 5%), and women more likely than men to report abstaining from oral sex (8% vs. 6%). Race/ethnic differences in sexual initiation timing remained robust in the face of controls for both women and men. Understanding the timing at which adolescents and young adults transition to first vaginal and first oral sex is critical for sex education curriculum and policy makers.

The informativity of sound modulates crossmodal facilitation of visual discrimination: a fMRI study.

PubMed

Li, Qi; Yu, Hongtao; Li, Xiujun; Sun, Hongzan; Yang, Jingjing; Li, Chunlin

2017-01-18

Many studies have investigated behavioral crossmodal facilitation when a visual stimulus is accompanied by a concurrent task-irrelevant sound. Lippert and colleagues reported that a concurrent task-irrelevant sound reduced the uncertainty of the timing of the visual display and improved perceptional responses (informative sound). However, the neural mechanism by which the informativity of sound affected crossmodal facilitation of visual discrimination remained unclear. In this study, we used event-related functional MRI to investigate the neural mechanisms underlying the role of informativity of sound in crossmodal facilitation of visual discrimination. Significantly faster reaction times were observed when there was an informative relationship between auditory and visual stimuli. The functional MRI results showed sound informativity-induced activation enhancement including the left fusiform gyrus and the right lateral occipital complex. Further correlation analysis showed that the right lateral occipital complex was significantly correlated with the behavioral benefit in reaction times. This suggests that this region was modulated by the informative relationship within audiovisual stimuli that was learnt during the experiment, resulting in late-stage multisensory integration and enhanced behavioral responses.

Differential Risk for Late Adolescent Conduct Problems and Mood Dysregulation Among Children with Early Externalizing Behavior Problems

PubMed Central

Bierman, Karen L.

2016-01-01

To investigate the differential emergence of antisocial behaviors and mood dysregulation among children with externalizing problems, the present study prospectively followed 317 high-risk children with early externalizing problems from school entry (ages 5–7) to late adolescence (ages 17–19). Latent class analysis conducted on their conduct and mood symptoms in late adolescence revealed three distinct patterns of symptoms, characterized by: 1) criminal offenses, conduct disorder symptoms, and elevated anger (“conduct problems”), 2) elevated anger, dysphoric mood, and suicidal ideation (“mood dysregulation”), and 3) low levels of severe conduct and mood symptoms. A diathesis-stress model predicting the first two outcomes was tested. Elevated overt aggression at school entry uniquely predicted conduct problems in late adolescence, whereas elevated emotion dysregulation at school entry uniquely predicted mood dysregulation in late adolescence. Experiences of low parental warmth and peer rejection in middle childhood moderated the link between early emotion dysregulation and later mood dysregulation but did not moderate the link between early overt aggression and later conduct problems. Thus, among children with early externalizing behavior problems, increased risk for later antisocial behavior or mood dysfunction may be identifiable in early childhood based on levels of overt aggression and emotion dysregulation. For children with early emotion dysregulation, however, increased risk for mood dysregulation characterized by anger, dysphoric mood, and suicidality – possibly indicative of disruptive mood dysregulation disorder – emerges only in the presence of low parental warmth and/or peer rejection during middle childhood. PMID:25183553

Transplacental cocaine exposure. 2: Effects of cocaine dose and gestational timing.

PubMed

Wilkins, A S; Jones, K; Kosofsky, B E

1998-01-01

We have utilized a mouse model of transplacental cocaine exposure to investigate the effects of cocaine dose and gestational timing in altering brain and body growth and postnatal behavior in exposed offspring. Pregnant dams were injected with cocaine HCl at 40 mg/kg/day (COC 40) or 20 mg/kg/day (COC 20), or 10 mg/kg/day (COC 10) SC from embryonic day (E) 8 to E17, or cocaine HCl at 40 mg/kg/day SC from E8 to E13 (COC Early) or from E13 to E17 (COC Late) divided in two daily doses. COC 40 and COC Late dams, as well as dams in nutritionally paired control groups (injected with saline vehicle and pair-fed with the COC dams: SPF 40, SPF 20, SPF 10), demonstrated less weight gain than SAL controls (injected with saline vehicle and allowed access to food ad lib). The surrogate fostered offspring of COC 40 and SPF 40 dams demonstrated brain and body growth retardation [on postnatal day (P) 1 and P9] when compared to pups born to SAL dams. Offspring of COC Late, SPF 20, and SPF 10 dams demonstrated brain and body growth retardation on P1 when compared to pups born to SAL dams. Pups from all groups were tested for first-order Pavlovian conditioning on P9, or for the ability to ignore redundant information in a blocking paradigm on P50. Only COC 40 mice (i.e., offspring born to COC 40 dams) were unable to acquire an aversion to an odor previously paired with shock on P9. When compared with SAL controls, COC 40 mice (and to a less significant extent SPF 40 mice) demonstrated a persistent behavioral deficit in the blocking paradigm on P50, which may reflect alterations in selective attention. Correlation analyses indicated that the dose and gestational timing of transplacental cocaine exposure, and varying degrees of malnutrition, had effects on blocking performance, with greater prenatal cocaine exposure and increased prenatal malnutrition resulting in more significant behavioral impairments. A path regression analysis demonstrated independent and significant effects of prenatal cocaine as well as prenatal malnutrition in contributing to impaired performance in the blocking paradigm. As suggested by the clinical literature, our preclinical data support a model whereby the dose and duration of prenatal cocaine exposure have direct effects on offspring brain and body growth and on behavioral performance.

Behavioral Correlates of Prioritizing Popularity in Adolescence.

PubMed

van den Broek, Nina; Deutz, Marike H F; Schoneveld, Elke A; Burk, William J; Cillessen, Antonius H N

2016-12-01

Little is known about individual differences in adolescents' motivation to achieve and maintain popularity. This study examined the moderating effects of prioritizing popularity on the associations between popularity and adjustment outcomes in late adolescence. Participants were 314 Dutch eleventh-grade students (M age  = 16.83 years; 52 % male) who completed measures of popularity, prioritizing popularity, and prosocial, antisocial, and risk behaviors. It was hypothesized that associations between popularity and adjustment outcomes are stronger for adolescents who prioritize popularity. The results indicate that the combination of being popular and valuing popularity was strongly related to antisocial and risk behaviors, but not to prosocial behaviors. Adolescents' social status motivations thus play an important role in the association of popularity with antisocial and risk behaviors in late adolescence.

A new tephrochronology for early diverse stone tool technologies and long-distance raw material transport in the Middle to Late Pleistocene Kapthurin Formation, East Africa.

PubMed

Blegen, Nick; Jicha, Brian R; McBrearty, Sally

2018-05-09

The Middle to Late Pleistocene (780-10 ka) of East Africa records evidence of significant behavioral change, early fossils of Homo sapiens, and the dispersals of our species across and out of Africa. Studying human evolution in this time period thus requires an extensive and precise chronology relating behavioral evidence from archaeological sequences to aspects of hominin biology and evidence of past environments from fossils and geological sequences. Tephrochronology provides the chronostratigraphic resolution to achieve this through correlation and dating of volcanic ashes. The tephrochronology of the Kapthurin Formation presented here, based on tephra correlations and 40 Ar/ 39 Ar dates, provides new ages between 395.6 ± 3.5 ka and 465.3 ± 1.0 ka for nine sites showing diverse blade and Levallois methods of core reduction. These are >110 kyr older than previously known in East Africa. New 40 Ar/ 39 Ar dates provide a refined age of 222.5 ± 0.6 ka for early evidence of long-distance (166 km) obsidian transport at the Sibilo School Road Site. A tephra correlation between the Baringo and Victoria basins also provides a new date of ∼100 ka for the Middle Stone Age site of Keraswanin. By providing new and older dates for 11 sites containing several important aspects of hominin behavior and extending the chronology of the Kapthurin Formation forward by ∼130,000 years, the tephrochronology presented here contributes one of the longest and most refined chronostratigraphic frameworks of Middle through Late Pleistocene East Africa. This tephrochronology thus provides the foundation to understand the process of modern human behavioral evolution as it relates to biological and paleoenvironmental circumstances. Copyright © 2018 Elsevier Ltd. All rights reserved.

Fire and Thinning in an Ohio Oak Forest: Grid-Based Analyses of Fire Behavior, Environmental Conditions, and Tree Regeneration Across a Topographic Moisture Gradient

Treesearch

Louis Iverson; Anantha Prasad; Todd Hutchinson; Joanne Rebbeck; Daniel A. Yaussy

2004-01-01

Prescribed fire alone and in combination with thinning were accomplished in late 2000 to spring 2001 at Zaleski State Forest in southern Ohio. Sites were monitored before and after the treatments were applied. Light was assessed via hemispherical photographs taken in July 2000 and 2001. Oak and hickory seedlings and saplings were sampled during those same time periods...

Comparing Characteristics of Early-Onset Injection Drug Users to Those With Late-Onset Injection in Kermanshah, Iran.

PubMed

Jorjoran Shushtari, Zahra; Noroozi, Alireza; Mirzazadeh, Ali; Ahounbar, Elahe; Hajbi, Ahmad; Najafi, Mohammad; Bazrafshan, Ali; Farhadi, Mohammad Hossin; Farhoudian, Ali; Higgs, Peter; Shahboulagh, Farahnaz Mohammadi; Waye, Katherine; Noroozi, Mehdi

2017-05-12

Characteristics and behaviors of early-onset injection drug users are under studied topics in Iran. This study aimed to identify and compare the demographic characteristics as well as the drug using behaviors of early-onset and late-onset injection drug users in Kermanshah, West Iran. In this cross-sectional study using snowball and convenience sampling, we recruited 450 people during the Fall of 2014 from two drop in centers in Kermanshah, Iran. We collected data through face-to-face interviews. Early-onset injection is defined as whether the person reported their first injection at 22 years of age or younger. Subsequently, late-onset injection is defined as 23 years of age or older. We compared the characteristics of the two groups through both univariate and multiple logistic analyses. Overall, 54% (CI 95%: 44.3%, 62.2%) were early injectors. After controlling for low socioeconomic status, initiation of drug use at a young age, multiple drug use and methamphetamine use were all significantly associated with a higher likelihood of early-onset injection. Additionally, early-onset injection was associated with recent syringe borrowing (OR = 2.6, p = 0.001), recent syringe lending (OR = 1.4, p = 0.01), recent cooker sharing (OR = 3.2, p = 0.01) and injecting two or more times a day (OR = 2.2, p = 0.04). Early-onset injectors were more likely to report a lower socioeconomic status, initiation of first drug use at a younger age, using methamphetamine alongside polydrug use, and engaging in higher risk taking behaviors like borrowing needles. With these associations, the study emphasizes the need for drug-prevention programs to focus on the transition to injection drug use at younger ages.

Painful Medical Conditions and Alcohol Use: A Prospective Study Among Older Adults

PubMed Central

Brennan, Penny L.; Schutte, Kathleen K.; SooHoo, Sonya; Moos, Rudolf H.

2011-01-01

Objective To determine associations between older adults’ baseline painful medical conditions and their 10-year drinking behavior, and whether personal and life context characteristics moderate these associations. Method At baseline, then 1, 4, and 10 years later, late-middle-aged community residents (M=61 years; n=1,291) were surveyed regarding their painful medical conditions, use of alcohol, and personal and life context characteristics. Latent growth modeling was used to determine concurrent and prospective relationships between painful medical conditions and 10-year drinking behavior, and moderating effects of personal and life context characteristics on these relationships. Results At baseline, individuals reporting more numerous painful medical conditions consumed alcohol less frequently, but had more frequent drinking problems, than did individuals with fewer such conditions. Being female and having more interpersonal social resources strengthened the association between painful medical conditions and less ethanol consumed. For men more so than women, more numerous painful medical conditions were associated with more frequent drinking problems. Baseline painful medical conditions alone had no prospective effect on 10-year change in drinking behavior, but being older and having more interpersonal social resources made it more likely that baseline painful medical conditions would predict decline over time in frequency of alcohol consumption and drinking problems. Conclusions Late-middle-aged individuals who have more numerous painful medical conditions reduce alcohol consumption but nonetheless remain at risk for more frequent drinking problems. Gender, age, and interpersonal social resources moderate the influence of painful medical conditions on late-life alcohol use. These results imply that older individuals with pain are at little immediate or long-term risk for increased alcohol consumption, but clinicians should remain alert to drinking problems among their older pain patients, especially men. PMID:21668742

Working Memory Load and Negative Picture Processing: Neural and Behavioral Associations With Panic, Social Anxiety, and Positive Affect.

PubMed

MacNamara, Annmarie; Jackson, T Bryan; Fitzgerald, Jacklynn M; Hajcak, Greg; Phan, K Luan

2018-04-22

Internalizing disorders such as anxiety may be characterized by an imbalance between bottom-up (stimulus-driven) and top-down (goal-directed) attention. The late positive potential (LPP) can be used to assess these processes when task-irrelevant negative and neutral pictures are presented within a working memory paradigm. Prior work using this paradigm has found that working memory load reduces the picture-elicited LPP across participants; however, anxious individuals showed a reduced effect of working memory load on the LPP, suggesting increased distractibility. The current study assessed transdiagnostic associations between specific symptom dimensions of anxiety, the LPP, and behavior in a clinically representative, heterogeneous group of 76 treatment-seeking patients with internalizing disorders, who performed a working memory task interspersed with negative and neutral pictures. As expected, negative pictures enhanced the LPP, and working memory load reduced the LPP. Participants with higher social anxiety showed increased LPPs to negative stimuli during early and late portions of picture presentation. Panic symptoms were associated with reduced LPPs to negative pictures compared with neutral pictures as well as a reduced effect of working memory load on the LPP during the late time window. Reduced positive affect was associated with greater behavioral interference from negative pictures. Hypervigilance for negative stimuli was uniquely explained by social anxiety symptoms, whereas panic symptoms were associated with the opposing effect-blunted processing/avoidance of these stimuli. Panic symptoms were uniquely associated with reduced top-down control. Results reveal distinct associations between neural reactivity and anxiety symptom dimensions that transcend traditional diagnostic boundaries. Copyright © 2018 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

Modifiable Midlife Risk Factors for Late-Life Cognitive Impairment and Dementia

PubMed Central

Hughes, Tiffany F.; Ganguli, Mary

2009-01-01

The baby boom generation is approaching the age of greatest risk for cognitive impairment and dementia. There is growing interest in strategies to modify the environment in midlife to increase the probability of maintaining cognitive health in late life. Several potentially modifiable risk factors have been studied in relation to cognitive impairment and dementia in late life, but methodological limitations of observational research have resulted in some inconsistencies across studies. The most promising strategies are maintaining cardiovascular health, engagement in mental, physical, and social activities, using alcohol in moderation, abstaining from tobacco use, and following a heart-healthy diet. Other factors that may influence cognitive health are occupational attainment, depression, personality, exposure to general anesthesia, head injury, postmenopausal hormone therapy, non-steroidal anti-inflammatory medications, and nutritional supplements such as antioxidants. Some long-term observational studies initiated in midlife or earlier, and some randomized controlled trials, have examined the effects of specific cognitive health promotion behaviors in midlife on the risk of cognitive impairment in late life. Overall, these studies provide limited support for risk reduction at this time. Recommendations and challenges for developing effective strategies to reduce the burden of cognitive impairment and dementia in the future are discussed. PMID:19946443

Cannibalism in Tyrannosaurus rex

PubMed Central

Longrich, Nicholas R.; Horner, John R.; Erickson, Gregory M.; Currie, Philip J.

2010-01-01

Background Tyrannosaurus rex was one of the largest terrestrial carnivores of all time, and consequently its ecology and diet have been the focus of much discussion. However, there is little direct evidence of diet or feeding habits in this species. Methodology/Principal Findings Examination of museum collections has revealed four specimens of Tyrannosaurus rex that bear tooth marks made by large, carnivorous dinosaurs. Because Tyrannosaurus is the only large carnivore known from the Late Maastrichtian of western North America, we infer that Tyrannosaurus made these tooth marks. Conclusions/Significance The marks are interpreted as feeding traces and these fossils therefore record instances of cannibalism. Given that this behavior has a low preservation potential, cannibalism seems to have been a surprisingly common behavior in Tyrannosaurus, and this behavior may have been relatively common in carnivorous dinosaurs. PMID:20976177

Effects of Hatching Time on Behavior and Weight Development of Chickens

PubMed Central

Løtvedt, Pia; Jensen, Per

2014-01-01

The length of the embryonic period varies both among and within species and can affect the individual phenotype in many ways, both physiologically and behaviorally. In chickens, the hatch window may last 24–48 hours (up to 10% of the incubation time), and studies have shown that incubation length may affect post-hatch growth and physiology. However, little is known about effects on behavior. We therefore investigated how behavior variation correlates with hatching time in the early life of chickens. We also measured egg weight and egg weight loss in relation to hatching time, as well as post-hatch growth. For females, there was a negative correlation between hatch time and body weight from day 4 and throughout the experiment. For males, such a correlation was only observed when testing all hatched males up until day 10. The birds were exposed to a number of behavioral tests, and a principal components analysis was performed on the variables, resulting in four components. For the largest component, termed “Passivity”, a tendency of a difference was found between early and middle male hatchers. Furthermore, a significant difference between early and middle male hatchers was found in the second component, termed “Response to novelty”. In a spatial learning test, late hatchers tended to learn slower. The behavior of females was not significantly affected by hatching time in any of these tests. This study is among the first to demonstrate a link between time of hatching and early behavior in a precocial species like the chicken, and may help shedding light on the evolutionary trade-offs between incubation length and post-hatch traits. The results may also be relevant from a perspective of stress coping and therefore also for animal welfare and productivity in the chicken industry. The mechanisms linking hatching time with post-hatch phenotype remain to be investigated. PMID:25058654

Psychological Symptoms, Social Outcomes, Socioeconomic Attainment, and Health Behaviors Among Survivors of Childhood Cancer: Current State of the Literature.

PubMed

Brinkman, Tara M; Recklitis, Christopher J; Michel, Gisela; Grootenhuis, Martha A; Klosky, James L

2018-06-06

The diagnosis, treatment, and medical late effects of childhood cancer may alter the psychosocial trajectory of survivors across their life course. This review of the literature focuses on mental health symptoms, achievement of social milestones, socioeconomic attainment, and risky health behaviors in survivors of childhood cancer. Results suggest that although most survivors are psychologically well adjusted, survivors are at risk for anxiety and depression compared with siblings. Although the absolute risk of suicide ideation and post-traumatic stress symptoms is low, adult survivors are at increased risk compared with controls. Moreover, young adult survivors are at risk for delayed psychosexual development, lower rates of marriage or cohabitation, and nonindependent living. Survivors' socioeconomic attainment also is reduced, with fewer survivors graduating college and gaining full-time employment. Despite risk for late health-related complications, survivors of childhood cancer generally engage in risky health behaviors at rates similar to or only slightly lower than siblings and peers. CNS tumors and CNS-directed therapies are salient risk factors for poor psychosocial outcomes. In addition, physical health morbidities resulting from cancer-directed therapies are associated with worse psychosocial functioning. Several studies support the effectiveness of cognitive and behavioral interventions to treat psychological symptoms as well as to modify health behaviors. Additional randomized controlled trials are needed to evaluate the efficacy and long-term outcomes of intervention efforts. Future research should focus on the identification of potential genetic predispositions related to psychosocial outcomes to provide opportunities for preventive interventions among survivors of childhood cancer.

[Behavior of late ventricular potentials in acute experimental myocardial ischemia].

PubMed

Duck, H J; Pankau, H; Köhler, H

1985-06-01

Locally retarded depolarizations of the ischaemic myocardium are regarded as frequent trigger mechanisms of dangerous ventricular arrhythmias. Up to now, however, there are scarcely systematic investigations concerning their concrete developmental conditions in man, since late potentials can be made evident only by means of expensive invasive methods or signal mediation techniques. Therefore, an animal model should be built, which is suitable for the control of new therapy conceptions with antiarrhythmic drugs. The investigations were performed on 22 pigs in whom under insufflation anaesthesia altogether 10 pressure, flow and contractility parameters as well as 6 epicardial ECG signals were continuously recorded. The episodes of ischaemia were caused by LAD occlusions of different duration and intensity. Typical late potentials could be registered in 5 animals who all had survived complete interruptions of the coronary blood flow of longer than 10 min. The mean duration of the late potentials was 20 +/- 9.2 ms, their amplitudes reached from 150 to 600 microV. Also with regard to time and cycle constancy, the delay of the late Q-potential and the morphology they corresponded to the homogeneous phenomenon, known from man. They always could be derived only from electrodes outside the immediate zone of ischaemia. Neither partial occlusions nor complete interruption of the coronary blood flow in intervals shorter than 10 minutes led to the development of a late potential. The animal model used altogether appears very suitable to investigate the medicamentous influencibility of arrhythmogenic areas of the myocardium under direct control of the dynamic behaviour of ventricular late potentials.

Developmental antecedents of abnormal eating attitudes and behaviors in adolescence.

PubMed

Le Grange, Daniel; O'Connor, Meredith; Hughes, Elizabeth K; Macdonald, Jacqui; Little, Keriann; Olsson, Craig A

2014-11-01

This study capitalizes on developmental data from an Australian population-based birth cohort to identify developmental markers of abnormal eating attitudes and behaviors in adolescence. The aims were twofold: (1) to develop a comprehensive path model identifying infant and childhood developmental correlates of Abnormal Eating Attitudes and Behaviors in adolescence, and (2) to explore potential gender differences. Data were drawn from a 30-year longitudinal study that has followed the health and development of a population based cohort across 15 waves of data collection from infancy since 1983: The Australian Temperament Project. Participants in this analysis were the 1,300 youth who completed the 11th survey at 15-16 years (1998) and who completed the eating disorder inventory at this time point. Developmental correlates of Abnormal Eating Attitudes and Behaviors in mid-adolescence were temperamental persistence, early gestational age, persistent high weight, teen depression, stronger peer relationships, maternal dieting behavior, and pubertal timing. Overall, these factors accounted for 28% of the variance in Abnormal Eating Attitudes and Behaviors at 15-16 years of age. Depressive symptoms, maternal dieting behavior, and early puberty were more important factors for girls. Late puberty was a more important factor for boys. Findings address an important gap in our understanding of the etiology of Abnormal Eating Attitudes and Behaviors in adolescence and suggest multiple targets for preventive intervention. © 2014 Wiley Periodicals, Inc.

Effects of prenatal dexamethasone treatment on physical growth, pituitary-adrenal hormones, and performance of motor, motivational, and cognitive tasks in juvenile and adolescent common marmoset monkeys.

PubMed

Hauser, Jonas; Knapman, Alana; Zürcher, Nicole R; Pilloud, Sonia; Maier, Claudia; Diaz-Heijtz, Rochellys; Forssberg, Hans; Dettling, Andrea; Feldon, Joram; Pryce, Christopher R

2008-12-01

Synthetic glucocorticoids such as dexamethasone (DEX) are commonly used to prevent respiratory distress syndrome in preterm infants, but there is emerging evidence of subsequent neurobehavioral abnormalities (e.g. problems with inattention/hyperactivity). In the present study, we exposed pregnant common marmosets (Callithrix jacchus, primates) to daily repeated DEX (5 mg/kg by mouth) during either early (d 42-48) or late (d 90-96) pregnancy (gestation period of 144 days). Relative to control, and with a longitudinal design, we investigated DEX effects in offspring in terms of physical growth, plasma ACTH and cortisol titers, social and maintenance behaviors, skilled motor reaching, motivation for palatable reward, and learning between infancy and adolescence. Early DEX resulted in reduced sociability in infants and increased motivation for palatable reward in adolescents. Late DEX resulted in a mild transient increase in knee-heel length in infants and enhanced reversal learning of stimulus-reward association in adolescents. There was no effect of either early or late DEX on basal plasma ACTH or cortisol titers. Both treatments resulted in impaired skilled motor reaching in juveniles, which attenuated in early DEX but persisted in late DEX across test sessions. The increased palatable-reward motivation and decreased social motivation observed in early DEX subjects provide experimental support for the clinical reports that prenatal glucocorticoid treatment impairs social development and predisposes to metabolic syndrome. These novel primate findings indicate that fetal glucocorticoid overexposure can lead to abnormal development of motor, affective, and cognitive behaviors. Importantly, the outcome is highly dependent upon the timing of glucocorticoid overexposure.

Too hot to handle? Analytic solutions for massive neutrino or warm dark matter cosmologies

NASA Astrophysics Data System (ADS)

Slepian, Zachary; Portillo, Stephen K. N.

2018-05-01

We obtain novel closed-form solutions to the Friedmann equation for cosmological models containing a component whose equation of state is that of radiation (w = 1/3) at early times and that of cold pressureless matter (w = 0) at late times. The equation of state smoothly transitions from the early to late-time behavior and exactly describes the evolution of a species with a Dirac Delta function distribution in momentum magnitudes |p_0| (i.e. all particles have the same |p_0|). Such a component, here termed "hot matter", is an approximate model for both neutrinos and warm dark matter. We consider it alone and in combination with cold matter and with radiation, also obtaining closed-form solutions for the growth of super-horizon perturbations in each case. The idealized model recovers t(a) to better than 1.5% accuracy for all a relative to a Fermi-Dirac distribution (as describes neutrinos). We conclude by adding the second moment of the distribution to our exact solution and then generalizing to include all moments of an arbitrary momentum distribution in a closed-form solution.

Fetal size in mid- and late pregnancy is related to infant alertness: the generation R study.

PubMed

Henrichs, Jens; Schenk, Jacqueline J; Schmidt, Henk G; Arends, Lidia R; Steegers, Eric A P; Hofman, Albert; Jaddoe, Vincent W V; Verhulst, Frank C; Tiemeier, Henning

2009-03-01

The vulnerability for behavioral problems is partly shaped in fetal life. Numerous studies have related indicators of intrauterine growth, for example, birth weight and body size, to behavioral development. We investigated whether fetal size in mid- and late pregnancy is related to infant irritability and alertness. In a population-based birth cohort of 4,255 singleton full-term infants ultrasound measurements of fetal head and abdominal circumference in mid- and late pregnancy were performed. Infant irritability and alertness scores were obtained by the Mother and Baby Scales at 3 months and z-standardized. Multiple linear regression analyses revealed curvilinear associations (inverted J-shape) of measures of fetal size in both mid- and late pregnancy with infant alertness. Fetal size characteristics were not associated with infant irritability. These results suggest that alterations of intrauterine growth affecting infant alertness are already detectable from mid-pregnancy onwards.

Responsiveness of the quality of life in late-stage dementia scale to psychotropic drug treatment in late-stage dementia.

PubMed

Martin-Cook, Kristin; Hynan, Linda S; Rice-Koch, Kathleen; Svetlik, Doris A; Weiner, Myron F

2005-01-01

We report on the responsiveness of a previously validated quality-of-life scale, the Quality of Life in Late-Stage Dementia scale (QUALID), as an outcome measure in a clinical trial of two psychotropic medications. Secondary analyses were conducted comparing outcome measures used in a randomized double-blind trial of two antipsychotics (olanzapine and risperidone) for the treatment of dementia-related behavioral symptoms. The QUALID was completed for 31 of the patients in addition to several measures of behavior-related dementia symptoms including the Neuropsychiatric Inventory, the Withdrawn Behavior subscale of the Multidimensional Observation Scale for Elderly Subjects, the Mini-Mental State Examination, and the Clinical Global Impression. Measures of safety and adverse effects included the Simpson-Angus Scale and records of specific adverse events. A significant positive relationship was found between QUALID score and improvement in behavioral symptoms, and a negative association was found with adverse medication effects. The QUALID was sensitive to both the treatment effects and the adverse effects of medication in this sample of patients.

Principals in Late Career: Toward a Conceptualization of Principals' Tasks and Experiences in the Pre-Retirement Period

ERIC Educational Resources Information Center

Oplatka, Izhar

2010-01-01

Purpose: To fill the gap in theoretical and empirical knowledge on late career in principalship, the aim of this study was to explore the career experiences, needs, and behaviors of principals at this stage. Research method: Life history and semistructured interviews were conducted with 20 late-career principals, 20 schoolteachers, and 10…

Longitudinal Relations Among Negative Affect, Substance Use and Peer Deviance During the Transition from Middle to Late Adolescence

PubMed Central

Mason, W. Alex; Hitchings, Julia E.; Spoth, Richard L.

2010-01-01

The transition from middle to late adolescence brings challenges that increase risk for emotional, behavioral, and social problems. The nature of the associations among these types of problems is poorly understood. This National Institute on Drug Abuse-funded study examined longitudinal relations among negative affect, substance use, and peer deviance from ages 16 to 18 years. Multiwave youth and parent questionnaire data collected from 429 6thgraders (222 girls) and their families residing in the rural Midwestern United States and recruited in 1993 were analyzed via structural equation modeling. Consistent with the self-medication hypothesis, negative affect statistically predicted increased substance use over time. Implications for theory and prevention are discussed and the study's limitations are noted. PMID:19544145

Case-control study on the associations between lifestyle-behavioral risk factors and phlegm-wetness constitution.

PubMed

Zhu, Yanbo; Wang, Qi; Dai, Zhaoyu; Origasa, Hideki; Di, Jie; Wang, Yangyang; Lin, Lin; Fan, Chunpok

2014-06-01

To explore the relationships between different lifestyle-behavioral factors and phlegm-wetness type of Traditional Chinese Medicine constitution, so as to provide health management strategies for phlegm-wetness constitution. A case-control study was conducted with the cases selected from the database of Chinese constitution survey in 9 provinces or municipalities of China. 1380 cases met the diagnostic criteria of phlegm-wetness type were taken as the case group, and 1380 cases were randomly selected from gentleness type as the control group. Using Chi-square test to compare the differences of lifestyle-behavior composition in each group; single factor and multiple logistic regression analysis were used to compare the relationships of lifestyle-behavioral factors and phlegm-wetness type. There were statistically significant differences between phlegm-wetness type group and gentleness type group in lifestyle behaviors (dietary habits, tobacco and liquor consumptions, exercise habits, sleeping habits). The results of single factor logistic regression analysis demonstrated that the risk of phlegm-wetness constitution decreased significantly in light diet (odds ratio, OR = 0.68); The risk factors of phlegm-wetness type were fatty food intake (OR = 2.36), sleeping early and getting up late (OR = 1.87), tobacco smoking (OR = 1.83), barbecued food intake (OR = 1.68), alcohol drinking (OR = 1.63), salty food intake (OR = 1.44), sleeping erratically (OR = 1.43), less physical activities (OR = 1.42), sweet food intake (OR = 1.29), sleeping and getting up late (OR = 1.26), and pungent food intake (OR = 1.21), respectively. Regardless of the interaction among lifestyle-behavioral factors, the results of the multiple logistic regression analysis revealed that the risk factors of phlegm-wetness type were sleeping early and getting up late (OR = 1.94), fatty food intake (OR = 1.80), tobacco smoking (OR = 1.50), sleeping erratically (OR = 1.50), barbecued food intake (OR = 1.40), sleeping and getting up late (OR = 1.40), less physical activities (OR = 1.31), sleeping late and getting up early (OR = 1.27), and sweet food intake (OR = 1.27, respectively, and the risk of phlegm-wetness type still decreased significantly in light food intake (OR = 0.79). Light diet can decrease the risk of being phlegm-wetness constitution, and bad lifestyle behaviors such as sleeping early and getting up late, sleeping erratically, fatty food, barbecued food or sweet food intake, tobacco and liquor consumptions, and less physical activities can increase the risks of becoming phlegm-wetness constitution.

Factors influencing young adults' attitudes and knowledge of late-life sexuality among older women.

PubMed

Allen, Rebecca S; Petro, Kathryn N; Phillips, Laura L

2009-03-01

Although sexuality is valued throughout the lifespan, older women's sexual expression can be influenced by physical, mental and social factors, including attitudes and stereotypes held by younger generations. By gaining an understanding of what influences negative attitudes toward sexuality and beliefs about sexual consent capacity, the stigma associated with sexuality in late life may be reduced. Using vignette methodology in an online survey, we examined older women's health and young adults' (N = 606; mean age = 18.86, SD = 1.42, range 17-36) general knowledge and attitudes toward aging and sexuality, personal sexual behavior, religious beliefs and perceived closeness with an older adult on attitudes towards sexual behavior and perceptions of consent capacity among older women. The health status of older women proved important in determining young adults' acceptance and perception of sexual consent capacity regarding late-life heterosexual/autoerotic and homosexual behaviors. Specifically, young adults expressed lower acceptance and more doubt regarding capacity to consent to sexual expression when the older woman was described as cognitively impaired. Additionally, young adults' personal attitudes toward late-life sexuality, but not knowledge, predicted acceptance toward sexual expression and belief in sexual consent capacity. Attention toward the influence of older women's cognitive health and young adults' attitudes toward late-life sexuality may prove beneficial in designing interventions to decrease the stigma associated with sexual activity in later life.

Does involvement in food preparation track from adolescence to young adulthood and is it associated with better dietary quality? Findings from a ten-year longitudinal study

PubMed Central

Larson, Nicole I.; Neumark-Sztainer, Dianne; Story, Mary

2012-01-01

Objectives To examine whether involvement in food preparation tracks over time, between adolescence (15–18 years), emerging adulthood (19–23 years), and the mid-to-late twenties (24–28 years), as well as examine 10-year longitudinal associations between home food preparation, dietary quality and meal patterning. Design Population-based, longitudinal cohort study. Setting Participants were originally sampled from Minnesota public secondary schools (USA). Subjects Participants enrolled in Project EAT (Eating Among Teens)-I, EAT-II, and EAT-III (n=1,321). Results Most participants in their mid-to-late twenties reported an enjoyment of cooking (73% of males, 80% of females); however, few prepared meals including vegetables most days of the week (24% males, 41% females). Participants in their mid-to-late twenties who enjoyed cooking were more likely to have engaged in food preparation as adolescents and emerging adults (p<0.01); those who frequently prepared meals including vegetables were more likely to have engaged in food preparation as emerging adults (p<0.001), but not adolescents. Emerging adult food preparation predicted better dietary quality five years later in the mid-to-late twenties, including higher intakes of fruit, vegetables, dark green/orange vegetables, and less sugar sweetened beverage and fast food consumption. Associations between adolescent food preparation and later dietary quality yielded few significant results. Conclusions Food preparation behaviors appeared to track over time, and engagement in food preparation during emerging adulthood, but not adolescence, was associated with healthier dietary intake during the mid-to-late twenties. Intervention studies are needed to understand whether promoting healthy food preparation results in improvements in eating patterns during the transition to adulthood. PMID:22124458

Brain-behavioral adaptability predicts response to cognitive behavioral therapy for emotional disorders: A person-centered event-related potential study.

PubMed

Stange, Jonathan P; MacNamara, Annmarie; Kennedy, Amy E; Hajcak, Greg; Phan, K Luan; Klumpp, Heide

2017-06-23

Single-trial-level analyses afford the ability to link neural indices of elaborative attention (such as the late positive potential [LPP], an event-related potential) with downstream markers of attentional processing (such as reaction time [RT]). This approach can provide useful information about individual differences in information processing, such as the ability to adapt behavior based on attentional demands ("brain-behavioral adaptability"). Anxiety and depression are associated with maladaptive information processing implicating aberrant cognition-emotion interactions, but whether brain-behavioral adaptability predicts response to psychotherapy is not known. We used a novel person-centered, trial-level analysis approach to link neural indices of stimulus processing to behavioral responses and to predict treatment outcome. Thirty-nine patients with anxiety and/or depression received 12 weeks of cognitive behavioral therapy (CBT). Prior to treatment, patients performed a speeded reaction-time task involving briefly-presented pairs of aversive and neutral pictures while electroencephalography was recorded. Multilevel modeling demonstrated that larger LPPs predicted slower responses on subsequent trials, suggesting that increased attention to the task-irrelevant nature of pictures interfered with reaction time on subsequent trials. Whereas using LPP and RT averages did not distinguish CBT responders from nonresponders, in trial-level analyses individuals who demonstrated greater ability to benefit behaviorally (i.e., faster RT) from smaller LPPs on the previous trial (greater brain-behavioral adaptability) were more likely to respond to treatment and showed greater improvements in depressive symptoms. These results highlight the utility of trial-level analyses to elucidate variability in within-subjects, brain-behavioral attentional coupling in the context of emotion processing, in predicting response to CBT for emotional disorders. Copyright © 2017 Elsevier Ltd. All rights reserved.

The effects of child maltreatment on early signs of antisocial behavior: Genetic moderation by Tryptophan Hydroxylase, Serotonin Transporter, and Monoamine Oxidase-A-Genes

PubMed Central

Cicchetti, Dante; Rogosch, Fred A.; Thibodeau, Eric

2013-01-01

Gene-environment interaction effects in predicting antisocial behavior in late childhood were investigated among maltreated and nonmaltreated low-income children (N = 627, M age = 11.27). Variants in three genes, TPH1, 5-HTTLPR, and MAOA uVNTR, were examined. In addition to child maltreatment status, we also considered the impact of maltreatment subtypes, developmental timing of maltreatment, and chronicity. Indicators of antisocial behavior were obtained from self-, peer-, and adult counselor-reports. In a series of ANCOVAs, child maltreatment and its parameters demonstrated strong main effects on early antisocial behavior as assessed by all forms of report. Genetic effects operated primarily in the context of gene-environment interactions, moderating the impact of child maltreatment on outcomes. Across the three genes, among nonmaltreated children no differences in antisocial behavior were found based on genetic variation. In contrast, among maltreated children specific polymorphisms of TPH1, 5-HTTLPR, and MAOA were each related to heightened self-report of antisocial behavior; the interaction of 5-HTTLPR and developmental timing of maltreatment also indicated more severe antisocial outcomes for children with early onset and recurrent maltreatment based on genotype. TPH1 and 5-HTTLPR interacted with maltreatment subtype to predict peer-report of antisocial behavior; genetic variation contributed to larger differences in antisocial behavior among abused children. TPH1 and 5-HTTLPR polymorphisms also moderated the effects of maltreatment subtype on adult report of antisocial behavior; again genetic effects were strongest for children who were abused. Additionally, TPH1 moderated the effect of developmental timing of maltreatment and chronicity on adult report of antisocial behavior. The findings elucidate how genetic variation contributes to identifying which maltreated children are most vulnerable to antisocial development. PMID:22781862

Personalizing behavioral interventions: the case of late-life depression

PubMed Central

Arean, Patricia A

2013-01-01

SUMMARY This article reviews the potential utility of behavioral interventions in personalized depression treatment. The paper begins with a definition of personalized treatment, moves to current thinking regarding the various causes of depression, and proposes how those causes can be used to inform the selection of behavioral interventions. Two examples from the late-life depression field will illustrate how a team of researchers at Cornell University (NY, USA) and University of California, San Francisco (CA, USA) created a research partnership to select and study behavioral interventions for older adults with risk factors associated with poor response to selective serotonin reuptake inhibitor medications. The paper ends with a discussion of how the process used by the Cornell University–University of California, San Francisco team can be applied to the selection and development of behavioral interventions for other psychiatric disorders. PMID:23646065

Randomized Controlled Trial for Behavioral Smoking and Weight Control Treatment: Effect of Concurrent versus Sequential Intervention

PubMed Central

Spring, Bonnie; Doran, Neal; Pagoto, Sherry; Schneider, Kristin; Pingitore, Regina; Hedeker, Don

2014-01-01

Prospects for changing multiple health behaviors conjointly remain controversial. We compared effects on tobacco abstinence and weight gain of adding diet and exercise concurrently or after smoking treatment. Female regular smokers (n=315) randomized to 3 conditions received 16 weeks of behavioral smoking treatment, quit at week 5, and were followed for 9 months after the quit date. Weight management was added to the first 8 weeks for Early Diet (ED), the final 8 weeks for Late Diet (LD), and omitted for Control. Both Diet groups tended to show greater bio-verified abstinence than Control although differences were nonsignificant. Compared to Control, ED initially suppressed weight gain but lost that effect over time, whereas LD initially lacked but gradually acquired a weight suppression effect that stabilized [p = .004]. Behavioral weight control did not undermine smoking cessation and slowed the rate of weight gain when initiated after the smoking quit date, supporting a sequential approach to multiple behavior change. PMID:15482037

Accelerating dark energy cosmological model in two fluids with hybrid scale factor

NASA Astrophysics Data System (ADS)

Mishra, B.; Sahoo, P. K.; Ray, Pratik P.

In this paper, we have investigated the anisotropic behavior of the accelerating universe in Bianchi V spacetime in the framework of General Relativity (GR). The matter field we have considered is of two non-interacting fluids, i.e. the usual string fluid and dark energy (DE) fluid. In order to represent the pressure anisotropy, the skewness parameters are introduced along three different spatial directions. To achieve a physically realistic solutions to the field equations, we have considered a scale factor, known as hybrid scale factor, which is generated by a time-varying deceleration parameter. This simulates a cosmic transition from early deceleration to late time acceleration. It is observed that the string fluid dominates the universe at early deceleration phase but does not affect nature of cosmic dynamics substantially at late phase, whereas the DE fluid dominates the universe in present time, which is in accordance with the observations results. Hence, we analyzed here the role of two fluids in the transitional phases of universe with respect to time which depicts the reason behind the cosmic expansion and DE. The role of DE with variable equation of state parameter (EoS) and skewness parameters, is also discussed along with physical and geometrical properties.

Simple cosmological model with inflation and late times acceleration

NASA Astrophysics Data System (ADS)

Szydłowski, Marek; Stachowski, Aleksander

2018-03-01

In the framework of polynomial Palatini cosmology, we investigate a simple cosmological homogeneous and isotropic model with matter in the Einstein frame. We show that in this model during cosmic evolution, early inflation appears and the accelerating phase of the expansion for the late times. In this frame we obtain the Friedmann equation with matter and dark energy in the form of a scalar field with a potential whose form is determined in a covariant way by the Ricci scalar of the FRW metric. The energy density of matter and dark energy are also parameterized through the Ricci scalar. Early inflation is obtained only for an infinitesimally small fraction of energy density of matter. Between the matter and dark energy, there exists an interaction because the dark energy is decaying. For the characterization of inflation we calculate the slow roll parameters and the constant roll parameter in terms of the Ricci scalar. We have found a characteristic behavior of the time dependence of density of dark energy on the cosmic time following the logistic-like curve which interpolates two almost constant value phases. From the required numbers of N-folds we have found a bound on the model parameter.

Association between walking, dysphoric mood and anxiety in late pregnancy: A cross-sectional study.

PubMed

Petrovic, Danica; Perovic, Milan; Lazovic, Biljana; Pantic, Igor

2016-12-30

Relationship between physical activity and mental disorders in late pregnancy is unclear. In this work, we demonstrate that there is a significant association between the time spent on walking and symptoms of depression and anxiety in antenatal period. The cross-sectional study was done on a sample of 200 healthy women in 9th month of physiological pregnancy at Health center Kraljevo, Serbia during 2015. Each participant was given a questionnaire consisting of general questions regarding physical activity, pregnancy, and other parameters. Also, each participant completed a Beck depression inventory (BDI) and Zung anxiety scale (ZAS). There was a statistically significant negative correlation (p<0.05) between the BDI score and the daily time spent on walking. There was also a strong positive connection between the daily time spent on walking and level of anxiety (p<0.01). To our knowledge this is the first study to jointly test the relationship between scores of Beck depression inventory and Zung anxiety scale, and time spent on walking as physical activity in antenatal period. The results represent the basis for further research in the field of gynecological psychology, psychiatry and behavioral physiology. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Future time perspective and positive health practices in young adults: an extension.

PubMed

Mahon, N E; Yarcheski, T J; Yarcheski, A

1997-06-01

A sample of 69 young adults attending a public university responded to the Future Time Perspective Inventory, two subscales of the Time Experience Scales (Fast and Slow Tempo), and the Personal Lifestyle Questionnaire in classroom settings. A statistically significant correlation (.52) was found between scores for future time perspective and the ratings for the practice of positive health behaviors in young adults. This correlation was larger than those previously found for middle and late adolescents. Scores on subscales of individual health practices and future time perspective indicated statistically significant correlations for five (.25 to .56) of the six subscales. Scores on neither Fast nor Slow Tempo were related to ratings of positive health practices or ratings on subscales measuring positive health practices.

Changes in processing of masked stimuli across early- and late-night sleep: a study on behavior and brain potentials.

PubMed

Verleger, Rolf; Schuknecht, Simon-Vitus; Jaśkowski, Piotr; Wagner, Ullrich

2008-11-01

Sleep has proven to support the memory consolidation in many tasks including learning of perceptual skills. Explicit, conscious types of memory have been demonstrated to benefit particularly from slow-wave sleep (SWS), implicit, non-conscious types particularly from rapid eye movement (REM) sleep. By comparing the effects of early-night sleep, rich in SWS, and late-night sleep, rich in REM sleep, we aimed to separate the contribution of these two sleep stages in a metacontrast masking paradigm in which explicit and implicit aspects in perceptual learning could be assessed separately by stimulus identification and priming, respectively. We assumed that early sleep intervening between two sessions of task performance would specifically support stimulus identification, while late sleep would specifically support priming. Apart from overt behavior, event-related EEG potentials (ERPs) were measured to record the cortical mechanisms associated with behavioral changes across sleep. In contrast to our hypothesis, late-night sleep appeared to be more important for changes of behavior, both for stimulus identification, which tended to improve across late-night sleep, and for priming, with the increase of errors induced by masked stimuli correlating with the duration of REM sleep. ERP components proved sensitive to presence of target shapes in the masked stimuli and to their priming effects. Of these components, the N2 component, indicating processing of conflict, became larger across early-night sleep and was related to the duration of S4 sleep, the deepest substage of SWS containing particularly high portions of EEG slow waves. These findings suggest that sleep promotes perceptual learning primarily by its REM sleep portion, but indirectly also by way of improved action monitoring supported by deep slow-wave sleep.

Diagnostic and Treatment Challenges of Sighted Non-24-Hour Sleep-Wake Disorder.

PubMed

Malkani, Roneil G; Abbott, Sabra M; Reid, Kathryn J; Zee, Phyllis C

2018-04-15

To report the diagnostic and treatment challenges of sighted non-24-hour sleep-wake disorder (N24SWD). We report a series of seven sighted patients with N24SWD clinically evaluated by history and sleep diaries, and when available wrist actigraphy and salivary melatonin levels, and treated with timed melatonin and bright light therapy. Most patients had a history of a delayed sleep-wake pattern prior to developing N24SWD. The typical sleep-wake pattern of N24SWD was seen in the sleep diaries (and in actigraphy when available) in all patients with a daily delay in midpoint of sleep ranging 0.8 to 1.8 hours. Salivary dim light melatonin onset (DLMO) was evaluated in four patients but was missed in one. The estimated phase angle from DLMO to sleep onset ranged from 5.25 to 9 hours. All six patients who attempted timed melatonin and bright light therapy were able to entrain their sleep-wake schedules. Entrainment occurred at a late circadian phase, possibly related to the late timing of melatonin administration, though the patients often preferred late sleep times. Most did not continue treatment and continued to have a non-24-hour sleep-wake pattern. N24SWD is a chronic debilitating disorder that is often overlooked in sighted people and can be challenging to diagnose and treat. Tools to assess circadian pattern and timing can be effectively applied to aid the diagnosis. The progressive delay of the circadian rhythm poses a challenge for determining the most effective timing for melatonin and bright light therapies. Furthermore, once the circadian sleep-wake rhythm is entrained, long-term effectiveness is limited because of the behavioral and environmental structure that is required to maintain stable entrainment. © 2018 American Academy of Sleep Medicine.

Modeling shade tree use by beef cattle as a function of black globe temperature and time of day

NASA Astrophysics Data System (ADS)

Foust, Amanda M.; Headlee, William L.

2017-12-01

Increasing temperatures associated with global climate change threaten to disrupt agricultural systems such as beef production, yet relatively little is known about the use of natural tree shade to mitigate the negative effects of heat stress on beef cattle. In this study, we evaluated how temperature and time of day influenced the utilization of tree shade in relation to coloration, orientation, and behavior of beef cattle in a pasture system. Temperatures in shade and direct sunlight were measured using black globe temperature (BGT) data loggers. Time-lapse images from game cameras were used to obtain counts of shade usage, coloration, orientation, and behavior of cattle throughout the daytime hours. In general, we found that shade utilization and most of the predominating orientations and behaviors differed significantly ( P < 0.05) by both time of day (Hour) and BGT in direct sunlight (BGTsun), while interactions between these two effects (Hour × BGTsun) were often nonsignificant. The mean percentage of the herd using shade was highest in mid-morning (87-96%) and early afternoon (97%), but also increased with BGTsun regardless of the time of day; these trends were similar for both dark- and light-colored cattle. Lying down was the dominant behavior exhibited in the shade, while foraging was the most prevalent behavior in the sun. When herd shade usage was lowest in mid- to late-afternoon (<1%) we also observed an increase in the use of heat-mitigating orientations in the sun (37-47%). We discuss some practical implications of these results, including the potential use of temperature thresholds to interpret cattle behaviors and shade usage.

Modeling shade tree use by beef cattle as a function of black globe temperature and time of day.

PubMed

Foust, Amanda M; Headlee, William L

2017-12-01

Increasing temperatures associated with global climate change threaten to disrupt agricultural systems such as beef production, yet relatively little is known about the use of natural tree shade to mitigate the negative effects of heat stress on beef cattle. In this study, we evaluated how temperature and time of day influenced the utilization of tree shade in relation to coloration, orientation, and behavior of beef cattle in a pasture system. Temperatures in shade and direct sunlight were measured using black globe temperature (BGT) data loggers. Time-lapse images from game cameras were used to obtain counts of shade usage, coloration, orientation, and behavior of cattle throughout the daytime hours. In general, we found that shade utilization and most of the predominating orientations and behaviors differed significantly (P < 0.05) by both time of day (Hour) and BGT in direct sunlight (BGT sun ), while interactions between these two effects (Hour × BGT sun ) were often nonsignificant. The mean percentage of the herd using shade was highest in mid-morning (87-96%) and early afternoon (97%), but also increased with BGT sun regardless of the time of day; these trends were similar for both dark- and light-colored cattle. Lying down was the dominant behavior exhibited in the shade, while foraging was the most prevalent behavior in the sun. When herd shade usage was lowest in mid- to late-afternoon (<1%) we also observed an increase in the use of heat-mitigating orientations in the sun (37-47%). We discuss some practical implications of these results, including the potential use of temperature thresholds to interpret cattle behaviors and shade usage.

The association between elevated blood lead levels and violent behavior during late adolescence: The South African Birth to Twenty Plus cohort.

PubMed

Nkomo, Palesa; Mathee, Angela; Naicker, Nisha; Galpin, Jacky; Richter, Linda M; Norris, Shane A

2017-12-01

Epidemiological studies have shown the adverse neuro-behavioral health effects of lead exposure among children, in particular. However, there is lack evidence in this regard from developing countries. The main aim of this study was to assess the association between blood lead levels (BLLs) during early adolescence and violent behavior in late adolescence. Our study sample from the Birth to Twenty Plus cohort in Soweto-Johannesburg, South Africa included 1332 study participants (684 females). BLLs were measured using blood samples collected at age 13years. Violent behavior was evaluated using data collected at ages 15 to 16years using the Youth Self Report questionnaire. First, bivariate analysis was used to examine data for an association between lead exposure in early adolescence and violent behavior items during late adolescence. Principal Component Analysis (PCA) was used for dimensionality reduction and six violent behavior components were derived. Data were further analyzed for an association between BLLs at age 13years and violent behavior using PCA derived components; to determine the specific type(s) of violent behavior associated with lead exposure. Median whole BLLs were 5.6μg/dL (p<0.001). Seventy five percent of males and 50% of females had BLLs≥5μg/dL. BLLs ranging from 5 to 9.99μg/dL were associated with physical violence (p=0.03) and BLLs≥10μg/dL were associated physical violence and fighting (p=0.02 and p=0.01, respectively). When data were analyzed using continuous BLLs physical violence was associated with lead exposure (p<0.0001). Furthermore, males were more likely to be involved in violence using a weapon (p=0.01), physical violence (p<0.0001), and robbing others (p<0.05) compared to females. The results from this study show the severe nature of violent behavior in late adolescence associated with childhood lead exposure. They highlight the urgent need for preventive measures against lead exposure among children in low or middle income countries such as South Africa. Copyright © 2017 Elsevier Ltd. All rights reserved.

Astrochronology of the Late Turonian: implications for the behavior of the carbon cycle at the demise of peak greenhouse

NASA Astrophysics Data System (ADS)

Laurin, Jiří; Čech, Stanislav; Uličný, David; Štaffen, Zdeněk; Svobodová, Marcela

2014-05-01

A series of prominent carbon-cycle perturbations, indicated by carbon-isotope excursions of up to 2‰, marked climatic and oceanographic changes that followed the peak mid-Cretaceous greenhouse. The nature and forcing mechanisms of these changes remain poorly understood, partly due to the lack of a detailed temporal control in this interval. Here we present an orbitally calibrated time scale, which is based on hemipelagic rhythmites in the Bohemian Cretaceous Basin, and which can be linked to the established chronostratigraphic framework using inoceramid biostratigraphy and carbon-isotope signature. In the new age model, the Late Turonian, defined by the first occurrence of I. perplexus below and the first occurrence of C. deformis erectus above, spans 1.56(±0.07) Myr. When anchored to the newly refined age of the Turonian-Coniacian boundary (Sageman et al., in press), the onset of the Late Turonian is 91.31(±0.45) Ma. Inoceramid zones I. perplexus and M. scupini span 0.76(±0.05) Myr and 0.80(±0.05) Myr, respectively. A time-domain record of carbon-isotope variations was obtained by pinning published δ13Ccarb data to the orbital time scale using 9 biostratigraphic and carbon-isotope markers. The timing of major carbon-isotope excursions suggests a link to 405-kyr eccentricity changes and, in the early Late Turonian, to ˜100 kyr eccentricity variations. However, over 80% of the variance in the Late Turonian δ13C occurs at longer (million-year) scales. The key features of the δ13Ccarb signature, including the amplified long-term variance, can be reproduced with simple models of orbitally driven isotopic mass balance. At a constant carbon-isotope fractionation, the best fit to the δ13Ccarb signature is obtained with enhanced organic burial at high eccentricity (in accordance with monsoonal forcing of organic accumulation in the low-latitude Atlantic and/or buildup of low-latitude, terrestrial carbon reservoirs). Alternative solutions should consider changing carbon-isotope fractionation due to pCO2 and/or nutrient-flux changes.

Behavioral and monoamine perturbations in adult male mice with chronic inflammation induced by repeated peripheral lipopolysaccharide administration.

PubMed

Krishna, Saritha; Dodd, Celia A; Filipov, Nikolay M

2016-04-01

Considering the limited information on the ability of chronic peripheral inflammation to induce behavioral alterations, including on their persistence after inflammatory stimuli termination and on associated neurochemical perturbations, this study assessed the effects of chronic (0.25 mg/kg; i.p.; twice weekly) lipopolysaccharide (LPS) treatment on selected behavioral, neurochemical and molecular measures at different time points in adult male C57BL/6 mice. Behaviorally, LPS-treated mice were hypoactive after 6 weeks, whereas significant hyperactivity was observed after 12 weeks of LPS and 11 weeks after 13 week LPS treatment termination. Similar biphasic responses, i.e., early decrease followed by a delayed increase were observed in the open field test center time, suggestive of, respectively, increased and decreased anxiety. In a forced swim test, mice exhibited increased immobility (depressive behavior) at all times they were tested. Chronic LPS also produced persistent increase in splenic serotonin (5-HT) and time-dependent, brain region-specific alterations in striatal and prefrontocortical dopamine and 5-HT homeostasis. Microglia, but not astrocytes, were activated by LPS early and late, but their activation did not persist after LPS treatment termination. Above findings demonstrate that chronic peripheral inflammation initially causes hypoactivity and increased anxiety, followed by persistent hyperactivity and decreased anxiety. Notably, chronic LPS-induced depressive behavior appears early, persists long after LPS termination, and is associated with increased splenic 5-HT. Collectively, our data highlight the need for a greater focus on the peripheral/central monoamine alterations and lasting behavioral deficits induced by chronic peripheral inflammation as there are many pathological conditions where inflammation of a chronic nature is a hallmark feature. Copyright © 2016 Elsevier B.V. All rights reserved.

Stroke preparedness in children: translating knowledge into behavioral intent: a systematic review and meta-analysis.

PubMed

Ottawa, Cassandra; Sposato, Luciano A; Nabbouh, Fadl; Saposnik, Gustavo

2015-10-01

If translated into behavioral intent, improving stroke knowledge may potentially impact on better outcomes. Children are an attractive target population since they can drive familial behavioral changes. However, the impact of interventions on stroke knowledge among children is unclear. We performed a systematic review and meta-analysis to investigate whether educational interventions targeting children improve stroke knowledge and lead to behavioral changes. We searched Ovid, PubMed, and Embase between January 2000 and December 2014. We included studies written in English reporting the number of children aged 6-15 years undergoing educational interventions on stroke and providing the results for baseline and early and late postintervention tests. We compared the proportion of correct answers between baseline, early, and late responses for two endpoints: knowledge and behavioral intent. Of the initial 58 articles found, we included nine that met the inclusion criteria. Compared with baseline tests (51·7%, 95% confidence interval 40·9-62·4), there was improvement in stroke knowledge in early (74·0%, 95% confidence interval 64·4-82·5, P = 0·002) and late (67·3%, 95% confidence interval 55·4-78·2, P = 0·027) responses. There was improvement in the early (92·1%, 95% confidence interval 86·0-96·6, P < 0·001) and late (83·9%, 95% confidence interval 73·5-92·1, P = 0·001) responses for behavioral intent compared with the baseline assessment (63·8%, 95% confidence interval 53·5-73·4). Children are a potentially attractive target population for improvement in stroke knowledge and behavioral intent, both in the short and long term. Our findings may support the implementation of large-scale stroke educational initiatives targeting children. © 2015 World Stroke Organization.

Temporal Dynamics of Sensorimotor Networks in Effort-Based Cost-Benefit Valuation: Early Emergence and Late Net Value Integration.

PubMed

Harris, Alison; Lim, Seung-Lark

2016-07-06

Although physical effort can impose significant costs on decision-making, when and how effort cost information is incorporated into choice remains contested, reflecting a larger debate over the role of sensorimotor networks in specifying behavior. Serial information processing models, in which motor circuits simply implement the output of cognitive systems, hypothesize that effort cost factors into decisions relatively late, via integration with stimulus values into net (combined) value signals in dorsomedial frontal cortex (dmFC). In contrast, ethology-inspired approaches suggest a more active role for the dorsal sensorimotor stream, with effort cost signals emerging rapidly after stimulus onset. Here we investigated the time course of effort cost integration using event-related potentials in hungry human subjects while they made decisions about expending physical effort for appetitive foods. Consistent with the ethological perspective, we found that effort cost was represented from as early as 100-250 ms after stimulus onset, localized to dorsal sensorimotor regions including middle cingulate, somatosensory, and motor/premotor cortices. However, examining the same data time-locked to motor output revealed net value signals combining stimulus value and effort cost approximately -400 ms before response, originating from sensorimotor areas including dmFC, precuneus, and posterior parietal cortex. Granger causal connectivity analysis of the motor effector signal in the time leading to response showed interactions between these sensorimotor regions and ventrolateral prefrontal cortex, a structure associated with adjusting behavior-response mappings. These results suggest that rapid activation of sensorimotor regions interacts with cognitive valuation systems, producing a net value signal reflecting both physical effort and reward contingencies. Although physical effort imposes a cost on choice, when and how effort cost influences neural correlates of decision-making remains contested. This dispute reflects a larger disagreement between cognitive neuroscience and ethology over the role of sensorimotor systems in behavior: are sensorimotor circuits merely implementing the late-stage output of cognitive systems, or engaged rapidly and interactively from early in decision-making? We find that, although early representation of effort cost is associated with sensorimotor regions, these signals are also integrated with cognitive stimulus value representations in the time leading up to motor response. These data suggest that sensorimotor networks interact dynamically with cognitive systems to guide decision-making, providing a first step toward reconciling differing perspectives on sensorimotor roles in valuation and choice. Copyright © 2016 the authors 0270-6474/16/367167-17$15.00/0.

Why are they late? Timing abilities and executive control among students with learning disabilities.

PubMed

Grinblat, Nufar; Rosenblum, Sara

2016-12-01

While a deficient ability to perform daily tasks on time has been reported among students with learning disabilities (LD), the underlying mechanism behind their 'being late' is still unclear. This study aimed to evaluate the organization in time, time estimation abilities, actual performance time pertaining to specific daily activities, as well as the executive functions of students with LD in comparison to those of controls, and to assess the relationships between these domains among each group. The participants were 27 students with LD, aged 20-30, and 32 gender and age-matched controls who completed the Time Organization and Participation Scale (TOPS) and the Behavioral Rating Inventory of Executive Function-Adult version (BRIEF-A). In addition, their ability to estimate the time needed to complete the task of preparing a cup of coffee as well as their actual performance time were evaluated. The results indicated that in comparison to controls, students with LD showed significantly inferior organization in time (TOPS) and executive function abilities (BRIEF-A). Furthermore, their time estimation abilities were significantly inferior and they required significantly more time to prepare a cup of coffee. Regression analysis identified the variables that predicted organization in time and task performance time among each group. The significance of the results for both theoretical and clinical implications are discussed. What this paper adds? This study examines the underlying mechanism of the phenomena of being late among students with LD. Following a recent call for using ecologically valid assessments, the functional daily ability of students with LD to prepare a cup of coffee and to organize time were investigated. Furthermore, their time estimation and executive control abilities were examined as a possible underlying mechanism for their lateness. Although previous studies have indicated executive control deficits among students with LD, to our knowledge, this is the first analysis of the relationships between their executive control and time estimation deficits and their influence upon their daily function and organization in time abilities. Our findings demonstrate that students with LD need more time in order to execute simple daily activities, such as preparing a cup of coffee. Deficient working memory, retrospective time estimation ability and inhibition predicted their performance time and organization in time abilities. Therefore, this paper sheds light on the mechanism behind daily performance in time among students with LD and emphasizes the need for future development of focused intervention programs to meet their unique needs. Copyright © 2016 Elsevier Ltd. All rights reserved.

Origin and mixing timescale of Earth's late veneer

NASA Astrophysics Data System (ADS)

Prescher, C.; Allu Peddinti, D.; Bell, E. A.; Bello, L.; Cernok, A.; Ghosh, N.; Tucker, J.; Wielicki, M. M.; Zahnle, K. J.

2012-12-01

Experimental studies on the partitioning behavior of highly siderophile elements (HSE) between silicate and metallic melts imply that the Earth's mantle should have been highly depleted in these elements by core formation in an early magma ocean. However, present HSE contents of the Earth's mantle are ~3 orders of magnitude higher than that expected by experiments. The apparent over-abundance of HSE has commonly been explained by the addition of meteoritic material in the "late veneer" which describes the exogenous mass addition following the moon forming impact and concluding with the late heavy bombardment at ~3.8-3.9 Ga. The strongest evidence for this theory is that the platinum group element (PGE) contents in today's mantle are present in chondritic relative abundances, as opposed to a fractionated pattern expected with metal-silicate partitioning. Archean komatiites indicate that the PGE content of the Earth's mantle increased from about half their present abundances at 3.5 Ga to their present abundances at 2.9 Ga. This secular increase in PGE content suggests a progressive mixing of the late veneer material into the Earth's mantle. However, this time scale also implies that the whole mantle was relatively well mixed by 2.9 Ga. We use a compilation of existing isotopic and trace element data in order to constrain the origin and composition of the late veneer. We use PGE abundances, W abundances and W isotopic compositions in chondritic meteorites and the primitive upper mantle to compute the amount of mass delivered during the late veneer and find the late veneer mass to be ~0.6 % the mass of the bulk silicate Earth (consistent with earlier estimates). We also use the 187Re-187Os and 190Pt-186Os systems to constrain the composition and timing of delivery of the impacting population. We model the efficiency of mantle mixing in this time frame by using 3-dimensional numerical geodynamical simulations and geochemical constraints. Initial parameters include the amount of mass delivered in the late veneer and the Archean internal heating which is at least 4 times higher than the present values, due to the higher abundance of radioactive elements. Another important parameter is the mechanism of mass addition to the Earth. We test three end-member scenarios: (1) a single very large impactor accounting for the entire mass addition, (2) sprinkling of a large number of small impactors over the whole Earth which then mix into the mantle, or (3) by using a size/frequency distribution estimated from the lunar cratering record and corrected for the difference in gravitational cross section of the Earth and the Moon. This project results from collaborations begun at the CIDER II workshop held at KITP, UCSB, 2012.

Alcohol Use During Pregnancy or Breastfeeding: A National Survey in France.

PubMed

Dumas, Agnès; Toutain, Stéphanie; Simmat-Durand, Laurence

2017-07-01

Adverse effects are associated with alcohol drinking during pregnancy and breastfeeding. Data are lacking on the size of the population at risk and on the characteristics of women engaging in risky behaviors such as daily consumption or repeated binge drinking. A cross-sectional survey was carried out by telephone among a nationally representative sample of pregnant and postpartum women. Frequency of alcohol use and binge drinking was retrospectively measured according to distinct time periods. Multivariable regression models were used to identify the characteristics of women reporting risk-taking behaviors. A total of 3,603 women participated. Daily consumption was reported by 0.1% of pregnant women and by 0.4% of breastfeeding women. In early pregnancy, 8.0% of women reported binge drinking (≥1 episode) and 1.2% reported repeated binge drinking (≥3 episodes). Binge drinking was estimated at 1.1% in late pregnancy and at 6.8% during breastfeeding. Characteristics of drinkers varied across these different drinking patterns and subpopulations. Moderate drinking during pregnancy and breastfeeding was associated with higher educational level. Smoking increased with increased frequency of alcohol use. Repeated binge drinking in early pregnancy was associated with late recognition of the pregnancy, while binge drinking in late pregnancy was associated with smoking. Daily alcohol use during pregnancy or breastfeeding was limited, while binge drinking in early pregnancy was reported by a large proportion of women. Demographic and socioeconomic characteristics of drinkers varied across drinking patterns.

Universal hydrodynamic flow in holographic planar shock collisions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chesler, Paul M.; Kilbertus, Niki; van der Schee, Wilke

2015-11-20

We study the collision of planar shock waves in AdS 5 as a function of shock profile. In the dual field theory the shock waves describe planar sheets of energy whose collision results in the formation of a plasma which behaves hydrodynamically at late times. We find that the post-collision stress tensor near the light cone exhibits transient non-universal behavior which depends on both the shock width and the precise functional form of the shock profile. However, over a large range of shock widths, including those which yield qualitative different behavior near the future light cone, and for different shockmore » profiles, we find universal behavior in the subsequent hydrodynamic evolution. In addition, we compute the rapidity distribution of produced particles and find it to be well described by a Gaussian.« less

Behavioral characteristics of Hanwoo (Bos taurus coreanae) steers at different growth stages and seasons.

PubMed

Kim, Na Yeon; Kim, Seong Jin; Jang, Se Young; Oh, Mi Rae; Tang, Yu Jiao; Seong, Hye Jin; Yun, Yeong Sik; Moon, Sang Ho

2017-10-01

This research analyzed behavioral characteristics of Hanwoo ( Bos taurus coreanae ) steers during each season and growth stage to enable measurement of the animals' welfare level for precision livestock farming. A hundred-eight beef steers were divided into three equal groups at a Hanwoo farm according to their growth stage: growing stage (GS), 8 months; early-fattening stage (EFS), 19 months; and late-fattening stage (LFS), 30 months. Twelve behavioral categories were continuously recorded for 13 day-time hours in each four seasons with three replications. Time spent standing was found to be significantly longer in summer at all growth stages (p<0.05). Hanwoos at the GS spent significantly longer standing time in spring and summer than those at the EFS and LFS (p<0.05). Lying time in summer was the shortest for all growth stages (p<0.05). Steers at the LFS spent significantly longer lying time than that at the GS (p<0.05) in summer. For GS and EFS, time spent eating in spring and autumn were longer than in summer and winter (p<0.05). Eating time was the longest for the GS in spring, autumn, and winter, excluding for the LFS in winter (p<0.05). Regarding ruminating, steers at the LFS spent significantly shorter time than those at other stages in all seasons (p<0.05). GS and EFS steers showed the longest walking time in summer compared with other seasons (p<0.05). At GS and LFS, drinking time in summer was the longest of all seasons (p<0.05). Sleeping time was significantly shorter in summer compared with the other seasons (p<0.05). Self-grooming time was the longest in winter for all growth stages (p<0.05). Steers were found to have more variable behavioral patterns during summer and the GS and less active behaviors during the LFS, thus extra care seems necessary during the GS, LFS, and summer period.

Responses to novel odors mediate maternal behavior and concaveation in gerbils.

PubMed

Clark, M M; Spencer, C A; Galef, B G

1986-01-01

In a series of three experiments we examined: (Experiment 1) responses to novel odors by early- and late-maturing not-pregnant, pregnant, nursing and postweaning female Mongolian gerbils, (Experiment 2) the response of the same eight groups of female gerbils to unfamiliar pups, and (Experiment 3) the rate of induction of maternal behavior by concaveation in early- and late-maturing nulliparous gerbils. We found: (1) that those females that responded relatively positively to novel odors in Experiment 1 were more likely to retrieve and less likely to attack unfamiliar pups in Experiment 2 than those females responding relatively negatively to novel odors in Experiment 1, and (2) that early-maturing nulliparous gerbils both responded more positively to novel odors and exhibited more rapid induction of maternal behavior by concaveation than late-maturing nulliparous gerbils. The results both confirm and extend Fleming and Rosenblatt's (1974) hypothesis that differences in response to novel odors mediate individual differences in maternal responsiveness.

The association of measures of the serotonin system, personality, alcohol use, and smoking with risk-taking traffic behavior in adolescents in a longitudinal study.

PubMed

Luht, Kadi; Eensoo, Diva; Tooding, Liina-Mai; Harro, Jaanus

2018-01-01

Studies on the neurobiological basis of risk-taking behavior have most often focused on the serotonin system. The promoter region of the gene encoding the serotonin transporter contains a polymorphic site (5-HTTLPR) that is important for the transcriptional activity, and studies have demonstrated its association with brain activity and behavior. Another molecular mechanism that reflects the capacity of the central serotonin system is the activity of the enzyme monoamine oxidase (MAO) as measured in platelets. The purpose of the present study was to examine how measures of the serotonin system (platelet MAO activity and the 5-HTTLPR polymorphism), personality variables, alcohol use and smoking are associated with risk-taking traffic behavior in schoolchildren through late adolescence. The younger cohort of the longitudinal Estonian Children Personality Behaviour and Health Study (originally n = 583) filled in questionnaires about personality traits, smoking status, alcohol use and traffic behavior at age 15 and 18 years. From venous blood samples, platelet MAO activity was measured radioenzymatically and 5-HTTLPR was genotyped. During late adolescence, subjects with lower platelet MAO activity were more likely to belong to the high-risk traffic behavior group. Male 5-HTTLPRs'-allele carriers were more likely to belong to the high-risk traffic behavior group compared to the l'/l' homozygotes. Other variables predicting risk group were alcohol use, smoking and Maladaptive impulsivity.The results suggest that lower capacity of the serotoninergic system is associated with more risky traffic behavior during late adolescence, but possibly by different mechanisms in boys and girls.

Reward-related brain function and sleep in pre/early pubertal and mid/late pubertal adolescents.

PubMed

Holm, Stephanie M; Forbes, Erika E; Ryan, Neal D; Phillips, Mary L; Tarr, Jill A; Dahl, Ronald E

2009-10-01

The onset of adolescence is a time of dramatic changes, including changes in sleep, and a time of new health concerns related to increases in risk-taking, sensation seeking, depression, substance use, and accidents. As part of a larger study examining puberty-specific changes in adolescents' reward-related brain function, the current article focuses on the relationship between functional neuroimaging measures of reward and measures of sleep. A total of 58 healthy participants 11-13 years of age completed a functional magnetic resonance imaging scan using a guessing task with monetary rewards and 4 days of at-home actigraphy and self-reported sleep ratings. Sleep variables included actigraph measures of mean weekend minutes asleep, sleep onset time, and sleep offset time, as well as self-reported sleep quality. During reward anticipation, less activation in the caudate (part of the ventral striatum) was associated with fewer minutes asleep, later sleep onset time, and lower sleep quality. During reward outcome, less caudate activation was associated with later sleep onset time, earlier sleep offset time, and lower sleep quality. It has been hypothesized that adolescents' low reactivity in reward-related brain areas could lead to compensatory increases in reward-driven behavior. This study's findings suggest that sleep could contribute to such behavior. Because decreased sleep has been associated with risky behavior and negative mood, these findings raise concerns about a negative spiral whereby the effects of puberty and sleep deprivation may have synergistic effects on reward processing, contributing to adolescent behavioral and emotional health problems.

Linking aquifer spatial properties and non-Fickian transport in mobile-immobile like alluvial settings

USGS Publications Warehouse

Zhang, Yong; Green, Christopher T.; Baeumer, Boris

2014-01-01

Time-nonlocal transport models can describe non-Fickian diffusion observed in geological media, but the physical meaning of parameters can be ambiguous, and most applications are limited to curve-fitting. This study explores methods for predicting the parameters of a temporally tempered Lévy motion (TTLM) model for transient sub-diffusion in mobile–immobile like alluvial settings represented by high-resolution hydrofacies models. The TTLM model is a concise multi-rate mass transfer (MRMT) model that describes a linear mass transfer process where the transfer kinetics and late-time transport behavior are controlled by properties of the host medium, especially the immobile domain. The intrinsic connection between the MRMT and TTLM models helps to estimate the main time-nonlocal parameters in the TTLM model (which are the time scale index, the capacity coefficient, and the truncation parameter) either semi-analytically or empirically from the measurable aquifer properties. Further applications show that the TTLM model captures the observed solute snapshots, the breakthrough curves, and the spatial moments of plumes up to the fourth order. Most importantly, the a priori estimation of the time-nonlocal parameters outside of any breakthrough fitting procedure provides a reliable “blind” prediction of the late-time dynamics of subdiffusion observed in a spectrum of alluvial settings. Predictability of the time-nonlocal parameters may be due to the fact that the late-time subdiffusion is not affected by the exact location of each immobile zone, but rather is controlled by the time spent in immobile blocks surrounding the pathway of solute particles. Results also show that the effective dispersion coefficient has to be fitted due to the scale effect of transport, and the mean velocity can differ from local measurements or volume averages. The link between medium heterogeneity and time-nonlocal parameters will help to improve model predictability for non-Fickian transport in alluvial settings.

Implications of Atmospheric Test Fallout Data for Nuclear Winter.

NASA Astrophysics Data System (ADS)

Baker, George Harold, III

1987-09-01

Atmospheric test fallout data have been used to determine admissable dust particle size distributions for nuclear winter studies. The research was originally motivated by extreme differences noted in the magnitude and longevity of dust effects predicted by particle size distributions routinely used in fallout predictions versus those used for nuclear winter studies. Three different sets of historical data have been analyzed: (1) Stratospheric burden of Strontium -90 and Tungsten-185, 1954-1967 (92 contributing events); (2) Continental U.S. Strontium-90 fallout through 1958 (75 contributing events); (3) Local Fallout from selected Nevada tests (16 events). The contribution of dust to possible long term climate effects following a nuclear exchange depends strongly on the particle size distribution. The distribution affects both the atmospheric residence time and optical depth. One dimensional models of stratospheric/tropospheric fallout removal were developed and used to identify optimum particle distributions. Results indicate that particle distributions which properly predict bulk stratospheric activity transfer tend to be somewhat smaller than number size distributions used in initial nuclear winter studies. In addition, both ^{90}Sr and ^ {185}W fallout behavior is better predicted by the lognormal distribution function than the prevalent power law hybrid function. It is shown that the power law behavior of particle samples may well be an aberration of gravitational cloud stratification. Results support the possible existence of two independent particle size distributions in clouds generated by surface or near surface bursts. One distribution governs late time stratospheric fallout, the other governs early time fallout. A bimodal lognormal distribution is proposed to describe the cloud particle population. The distribution predicts higher initial sunlight attenuation and lower late time attenuation than the power law hybrid function used in initial nuclear winter studies.

The hormonal and behavioral response to group formation, seasonal changes, and restraint stress in the highly social Malayan Flying Fox (Pteropus vampyrus) and the less social Little Golden-mantled Flying Fox (Pteropus pumilus) (Chiroptera: Pteropodidae).

PubMed

Reeder, DeeAnn M; Kosteczko, Nicole S; Kunz, Thomas H; Widmaier, Eric P

2006-04-01

This study examined behavioral and physiological responses (changes in inter-animal spacing, total glucocorticoids, testosterone, and body mass) to the formation of breeding and same-sex groups in two bat species, the socially gregarious Malayan Flying Fox (Pteropus vampyrus) and the less social Little Golden-mantled Flying Fox (Pteropus pumilus). We hypothesized that social instability, especially in the breeding groups and especially in P. vampyrus, would result in elevated glucocorticoids and that social facilitation of breeding and/or male-male competition would result in persistently higher levels of testosterone in breeding males. Seasonal rhythms in all measures were also predicted, and the glucocorticoid stress response was expected to vary by sex, season, and group type. Nearly all animals responded to group formation with elevated glucocorticoids, but, for breeding animals (especially aggressive male P. vampyrus), these responses persisted over time. In both species, breeding group formation resulted in elevated testosterone in males. Glucocorticoids, testosterone, testes volume, and body mass generally peaked in the breeding season in males (late summer and early autumn), but the seasonal glucocorticoid peak in females occurred in late winter and early spring. All animals responded to restraint stress with elevations in glucocorticoids that largely did not differ by sex, time of year, reproductive condition, group type, or, in lactating females, the presence of her pup. Changes in both behavior and physiology were more evident in P. vampyrus than in P. pumilus, and we believe that their underlying social differences influenced their responses to group formation and to the changing seasonal environment.

Stereotypic behavior of a female Asiatic elephant (Elephas maximus) in a zoo.

PubMed

Elzanowski, Andrzej; Sergiel, Agnieszka

2006-01-01

This study recorded daytime behavior of a female Asiatic elephant at the Municipal Zoo, Wroclaw, Poland, in both an indoor pen and an outdoor paddock as continuous scan sampling for 140 hr, over 35 days in 1 year. Stereotypic sequences involved bouts of highly repetitive stereotypic movements and much more variable interbout behavior. The study found both stereotypic movements, nodding and body (corpus) swaying, were asymmetric, accompanied by protraction of the right hind leg and to-and-fro swinging of the trunk. The elephant spent 52% of the daytime in stereotypic movements, 3.5 times the level reported for females in other zoos' groups. The share of time devoted to stereotypic behavior was lowest in the summer when the elephant was regularly released to the paddock and highest in the late fall after she had stayed in the pen after months of days outside. This suggests that changes in the management routine enhance stereotypies. Comparing the summer and winter stable management periods, stereotypies were much more frequent in the indoor pen than the outdoor paddock, suggesting that the confinement to a barren pen contributed to the observed levels of stereotypies.

Visceral predictors of cardiovascular deconditioning in late middle-aged men

NASA Technical Reports Server (NTRS)

Goldwater, D. J.; De Roshia, C.; Natelson, B. H.; Levin, B. E.

1985-01-01

A number of visceral and behavioral factors connected with cardiovascular deconditioning were investigated, in order to identify a method for predicting the degree of orthostatic intolerance to spaceflight in several late-middle-aged men (55-65 years). Preliminary measurements were made of: mean arterial blood pressure plasma cortisol levels; and norepinephrine levels. Measurements of core temperature; plasma epinephrine level and subjective arousal from sleep were also obtained. Pairwise correlations were found for each of the variables and the time-to-blackout due centrifugal acceleration of up to +3 Gz. It is shown that the men with relatively low resting blood pressure were at greater risk of developing the clinical signs of cardiovascular deconditioning than were the men with higher basal blood pressure. Some applications of the experimental results to the development of selection criteria for Shuttle crews are discussed.

Cyclic spattering, seismic tremor, and surface fluctuation within a perched lava channel, Kīlauea Volcano

NASA Astrophysics Data System (ADS)

Patrick, Matthew R.; Orr, Tim; Wilson, David; Dow, David; Freeman, Richard

2011-08-01

In late 2007, a perched lava channel, built up to 45 m above the preexisting surface, developed during the ongoing eruption near Pu`u `Ō`ō cone on Kīlauea Volcano's east rift zone. The lava channel was segmented into four pools extending over a total of 1.4 km. From late October to mid-December, a cyclic behavior, consisting of steady lava level rise terminated by vigorous spattering and an abrupt drop in lava level, was commonly observed in pool 1. We use geologic observations, video, time-lapse camera images, and seismicity to characterize and understand this cyclic behavior. Spattering episodes occurred at intervals of 40-100 min during peak activity and involved small (5-10-m-high) fountains limited to the margins of the pool. Most spattering episodes had fountains which migrated downchannel. Each spattering episode was associated with a rapid lava level drop of about 1 m, which was concurrent with a conspicuous cigar-shaped tremor burst with peak frequencies of 4-5 Hz. We interpret this cyclic behavior to be gas pistoning, and this is the first documented instance of gas pistoning in lava well away from the deeper conduit. Our observations and data indicate that the gas pistoning was driven by gas accumulation beneath the visco-elastic component of the surface crust, contrary to other studies which attribute similar behavior to the periodic rise of gas slugs. The gas piston events typically had a gas mass of about 2,500 kg (similar to the explosions at Stromboli), with gas accumulation and release rates of about 1.1 and 5.7 kg s-1, respectively. The time-averaged gas output rate of the gas pistoning events accounted for about 1-2% of the total gas output rate of the east rift zone eruption.

Cyclic spattering, seismic tremor, and surface fluctuation within a perched lava channel, Kīlauea Volcano

USGS Publications Warehouse

Patrick, M.R.; Orr, T.; Wilson, D.; Dow, D.; Freeman, R.

2011-01-01

In late 2007, a perched lava channel, built up to 45 m above the preexisting surface, developed during the ongoing eruption near Pu‘u ‘Ō‘ō cone on Kīlauea Volcano’s east rift zone. The lava channel was segmented into four pools extending over a total of 1.4 km. From late October to mid-December, a cyclic behavior, consisting of steady lava level rise terminated by vigorous spattering and an abrupt drop in lava level, was commonly observed in pool 1. We use geologic observations, video, time-lapse camera images, and seismicity to characterize and understand this cyclic behavior. Spattering episodes occurred at intervals of 40–100 min during peak activity and involved small (5–10-m-high) fountains limited to the margins of the pool. Most spattering episodes had fountains which migrated downchannel. Each spattering episode was associated with a rapid lava level drop of about 1 m, which was concurrent with a conspicuous cigar-shaped tremor burst with peak frequencies of 4–5 Hz. We interpret this cyclic behavior to be gas pistoning, and this is the first documented instance of gas pistoning in lava well away from the deeper conduit. Our observations and data indicate that the gas pistoning was driven by gas accumulation beneath the visco-elastic component of the surface crust, contrary to other studies which attribute similar behavior to the periodic rise of gas slugs. The gas piston events typically had a gas mass of about 2,500 kg (similar to the explosions at Stromboli), with gas accumulation and release rates of about 1.1 and 5.7 kg s−1, respectively. The time-averaged gas output rate of the gas pistoning events accounted for about 1–2% of the total gas output rate of the east rift zone eruption.

Intellectual, Adaptive, and Behavioral Functioning in Children with Urea Cycle Disorders

PubMed Central

Krivitzky, Lauren; Babikian, Talin; Lee, HyeSeung; Thomas, Nina Hattiangadi; Burk-Paull, Karen L.; Batshaw, Mark L.

2009-01-01

Inborn errors of urea synthesis lead to an accumulation of ammonia in blood and brain, and result in high rates of mortality and neurodevelopmental disability. The current study seeks to characterize the cognitive, adaptive, and emotional/behavioral functioning of children with Urea Cycle Disorders (UCDs). These domains were measured through testing and parent questionnaires in 92 children with UCDs (33 neonatal onset, 59 late onset). Results indicate that children who present with neonatal onset have poorer outcome than those who present later in childhood. Approximately half of the children with neonatal onset performed in the range of intellectual disability (ID), including a substantial number (~30%) who were severely impaired. In comparison, only a quarter of the late onset group were in the range of ID. There is also evidence that the UCD group has difficulties in aspects of emotional/behavioral and executive skills domains. In conclusion, children with UCDs present with a wide spectrum of cognitive outcomes. Children with neonatal onset disease have a much higher likelihood of having an intellectual disability, which becomes even more evident with increasing age. However, even children with late onset UCDs demonstrate evidence of neurocognitive and behavioral impairment, particularly in aspects of attention and executive functioning. PMID:19287347

Fine Scale Baleen Whale Behavior Observed Via Tagging Over Daily Time Scales

DTIC Science & Technology

2014-09-30

During late fall 2013 and winter 2014, I built a data logger for the optical plankton counter ( OPC ) to facilitate its continued use on the NOAA Ship...Gordon Gunter. This ship has very long (> 5 km) of conducting sea cable, and we had communication issues with the OPC with the manufacturers...telemetry system over this long sea cable. To solve this problem, I adapted an existing data logger to provide power and log data from the OPC locally on

The mediation effect of menstrual phase on negative emotion processing: evidence from N2.

PubMed

Wu, Haiyan; Chen, Chunping; Cheng, Dazhi; Yang, Suyong; Huang, Ruiwang; Cacioppo, Stephanie; Luo, Yue-Jia

2014-01-01

Numerous studies have shown a 'negativity bias' in emotion processing and effect of menstrual phase on emotion processing. Most of these results, however, did not match the arousal of different types of stimuli. The present study examined the time course of negative emotion processing across different menstrual phases (e.g., late luteal/premenstrual phase and follicular phase) when the arousal level of negative and neutral stimuli was equal. Following previous studies, an oddball paradigm was utilized in present study. Participants viewed neutral and negative (highly (HN) and moderately negative (MN)) stimuli with matched arousal and were asked to make deviant vs. standard judgments. The behavioral results showed a higher accuracy for HN stimuli than neutral stimuli, and the other comparisons were not significant. The major event-related potential (ERP) finding was that N2 amplitude was larger for MN than neutral in the late luteal phase, whereas such difference was absent during the follicular phase. Moreover, The N2 for HN stimuli was larger in late luteal phase than in follicular phase. Therefore, female may be with higher sensitivity to MN stimuli during late luteal phase than during follicular phase when the arousal of stimuli was well controlled. These results provide additional insight to premenstrual affective syndrome and affective disorder.

Late Pleistocene age and archaeological context for the hominin calvaria from GvJm-22 (Lukenya Hill, Kenya)

PubMed Central

Tryon, Christian A.; Crevecoeur, Isabelle; Faith, J. Tyler; Ekshtain, Ravid; Nivens, Joelle; Patterson, David; Mbua, Emma N.; Spoor, Fred

2015-01-01

Kenya National Museums Lukenya Hill Hominid 1 (KNM-LH 1) is a Homo sapiens partial calvaria from site GvJm-22 at Lukenya Hill, Kenya, associated with Later Stone Age (LSA) archaeological deposits. KNM-LH 1 is securely dated to the Late Pleistocene, and samples a time and region important for understanding the origins of modern human diversity. A revised chronology based on 26 accelerator mass spectrometry radiocarbon dates on ostrich eggshells indicates an age range of 23,576–22,887 y B.P. for KNM-LH 1, confirming prior attribution to the Last Glacial Maximum. Additional dates extend the maximum age for archaeological deposits at GvJm-22 to >46,000 y B.P. (>46 kya). These dates are consistent with new analyses identifying both Middle Stone Age and LSA lithic technologies at the site, making GvJm-22 a rare eastern African record of major human behavioral shifts during the Late Pleistocene. Comparative morphometric analyses of the KNM-LH 1 cranium document the temporal and spatial complexity of early modern human morphological variability. Features of cranial shape distinguish KNM-LH 1 and other Middle and Late Pleistocene African fossils from crania of recent Africans and samples from Holocene LSA and European Upper Paleolithic sites. PMID:25730861

Applying Self-Determination Theory to Adolescent Sexual-Risk Behavior and Knowledge: A Structural Equation Model [Formula: see text].

PubMed

Riley, Bettina H; McDermott, Ryon C

2018-05-01

National health priorities identify adolescent sexual-risk behavior outcomes as research and intervention targets for mental health. Reduce sexual-risk behavioral outcomes by applying self-determination theory to focus on decision-making autonomy. This study examined late adolescents' recollections of parental autonomy support/sexual-risk communication experiences and autonomy motivation as predictors of sexual-risk behaviors/knowledge. A convenience sample ( N = 249) of 19- and 20-year-old university students completed self-report questionnaires. Structural equation modeling with latent variables examined direct/indirect effects in the hypothesized model. Parents contributed uniquely through sexual-risk communication and/or autonomy support to late adolescents' autonomous motivation. The final model evidenced acceptable fit and explained 12% of the variation in adolescent sexual-risk behavior, 7% in adolescent autonomous motivation, and 2% in adolescent sexual-risk knowledge. Psychiatric mental health nurses should conduct further research and design interventions promoting parent autonomy support and adolescent autonomous motivation to reduce sexual risk-behavior and increase sexual-risk knowledge.

Children of Depressed Mothers 1 Year After Remission of Maternal Depression: Findings From the StAR*D-Child Study

PubMed Central

Wickramaratne, Priya; Gameroff, Marc J.; Pilowsky, Daniel J.; Hughes, Carroll W.; Garber, Judy; Malloy, Erin; King, Cheryl; Cerda, Gabrielle; Sood, A. Bela; Alpert, Jonathan E.; Trivedi, Madhukar H.; Fava, Maurizio; Rush, A. John; Wisniewski, Stephen; Weissman, Myrna M.

2012-01-01

Objective Maternal major depressive disorder is an established risk factor for child psychopathology. The authors previously reported that 1 year after initiation of treatment for maternal depression, children of mothers whose depression remitted had significantly improved functioning and psychiatric symptoms. This study extends these findings by examining changes in psychiatric symptoms, behavioral problems, and functioning among children of depressed mothers during the first year after the mothers' remission from depression. Method Children were assessed at baseline and at 3-month intervals with the Schedule for Affective Disorders and Schizophrenia for School-Age Children–Present and Lifetime Version, the Child Behavior Checklist, and the Children's Global Assessment Scale for 1 year after their mothers' remission or for 2 years if the mothers did not remit. The authors compared children of early remitters (0–3 months; N=36), late remitters (3–12 months; N=28), and nonremitters (N=16). Results During the postremission year, children of early-remitting mothers showed significant improvement on all outcomes. Externalizing behavioral problems decreased in children of early- and late-remitting mothers but increased in children of nonremitting mothers. Psychiatric symptoms decreased significantly only in children of mothers who remitted, and functioning improved only in children of early-remitting mothers. Conclusions Remission of mothers' depression, regardless of its timing, appears to be related to decreases in problem behaviors and symptoms in their children over the year after remission. The favorable effect of mothers' remission on children's functioning was observed only in children of early-remitting mothers. PMID:21406462

Friendship Network Characteristics Are Associated with Physical Activity and Sedentary Behavior in Early Adolescence.

PubMed

Marks, Jennifer; de la Haye, Kayla; Barnett, Lisa M; Allender, Steven

2015-01-01

There is limited understanding of the association between peer social networks and physical activity (PA), sedentary and screen-related behaviors. This study reports on associations between personal network characteristics and these important health behaviors for early adolescents. Participants were 310 students, aged 11-13 years, from fifteen randomly selected Victorian primary schools (43% response rate). PA and sedentary behaviors were collected via accelerometer and self-report questionnaire, and anthropometric measures via trained researchers. Participants nominated up to fifteen friends, and described the frequency of interaction and perceived activity intensity of these friends. Personal network predictors were examined using regression modelling for PA and sedentary/screen behavior. Perceived activity levels of friends, and friendships with very frequent interaction were associated with outside-of-school PA and/or sedentary/screen time. Differences according to sex were also observed in the association between network characteristics and PA and sedentary time. A higher number of friends and greater proportion of same sex friends were associated with boys engaging in more moderate-to-vigorous PA outside of school hours. PA intensity during school-day breaks was positively associated with having a greater proportion of friends who played sports for girls, and a greater proportion of male friends for boys. Friendship network characteristics are associated with PA and sedentary/screen time in late childhood/early adolescence, and these associations differ by sex. The positive influence of very active peers may be a promising avenue to strengthen traditional interventions for the promotion of PA and reduction in screen time.

Friendship Network Characteristics Are Associated with Physical Activity and Sedentary Behavior in Early Adolescence

PubMed Central

Marks, Jennifer; de la Haye, Kayla; Barnett, Lisa M; Allender, Steven

2015-01-01

Introduction There is limited understanding of the association between peer social networks and physical activity (PA), sedentary and screen-related behaviors. This study reports on associations between personal network characteristics and these important health behaviors for early adolescents. Methods Participants were 310 students, aged 11–13 years, from fifteen randomly selected Victorian primary schools (43% response rate). PA and sedentary behaviors were collected via accelerometer and self-report questionnaire, and anthropometric measures via trained researchers. Participants nominated up to fifteen friends, and described the frequency of interaction and perceived activity intensity of these friends. Personal network predictors were examined using regression modelling for PA and sedentary/screen behavior. Results Perceived activity levels of friends, and friendships with very frequent interaction were associated with outside-of-school PA and/or sedentary/screen time. Differences according to sex were also observed in the association between network characteristics and PA and sedentary time. A higher number of friends and greater proportion of same sex friends were associated with boys engaging in more moderate-to-vigorous PA outside of school hours. PA intensity during school-day breaks was positively associated with having a greater proportion of friends who played sports for girls, and a greater proportion of male friends for boys. Conclusion Friendship network characteristics are associated with PA and sedentary/screen time in late childhood/early adolescence, and these associations differ by sex. The positive influence of very active peers may be a promising avenue to strengthen traditional interventions for the promotion of PA and reduction in screen time. PMID:26709924

Sexual behavior of gender-dysphoric individuals before gender-confirming interventions: a European multicenter study.

PubMed

Cerwenka, Susanne; Nieder, Timo O; Cohen-Kettenis, Peggy; De Cuypere, Griet; Haraldsen, Ira R Hebold; Kreukels, Baudewijntje P C; Richter-Appelt, Hertha

2014-01-01

A transsexual course of development that starts before puberty (early onset) or during or after puberty, respectively (late onset), may lead to diverse challenges in coping with sexual activity. The authors explored the sexual behavior of 380 adult male-to-female and female-to-male individuals diagnosed according to DSM-IV-TR criteria who had not yet undergone gender-confirming interventions. Data originated from the European Network for the Investigation of Gender Incongruence Initiative, conducted in Belgium, Germany, The Netherlands, and Norway. Information on outcome variables was collected using self-administered questionnaires at first clinical presentation. Compared with late-onset male-to-females, early-onset individuals tended to show sexual attraction toward males more frequently (50.5%), involve genitals less frequently in partner-related sexual activity, and consider penile sensations and orgasm as more negative. Early-onset female-to-males predominantly reported sexual attraction toward females (84.0%), whereas those with a late-onset more frequently showed other sexual attractions (41.7%). The study (a) shows that early- and late-onset male-to-females differ considerably with regard to coping strategies involving their body during sexual relations and (b) reveals initial insights into developmental pathways of late-onset female-to-males.

Time with Peers from Middle Childhood to Late Adolescence: Developmental Course and Adjustment Correlates

PubMed Central

Lam, Chun Bun; McHale, Susan M.; Crouter, Ann C.

2014-01-01

This study examined the developmental course and adjustment correlates of time with peers from age 8 to 18. On 7 occasions over 8 years, the two eldest siblings from 201 European American, working- and middle-class families provided questionnaire and/or phone diary data. Multilevel models revealed that girls’ time with mixed/opposite-sex peers increased beginning in middle childhood, but boys’ time increased beginning in early adolescence. For both girls and boys, time with same-sex peers peaked in mid-adolescence. At the within-person level, unsupervised time with mixed/opposite-sex peers longitudinally predicted problem behaviors and depressive symptoms, and supervised time with mixed/opposite-sex peers longitudinally predicted better school performance. Findings highlight the importance of social context in understanding peer involvement and its implications for youth development. PMID:24673293

Power-law expansion of the Universe from the bosonic Lorentzian type IIB matrix model

NASA Astrophysics Data System (ADS)

Ito, Yuta; Nishimura, Jun; Tsuchiya, Asato

2015-11-01

Recent studies on the Lorentzian version of the type IIB matrix model show that (3+1)D expanding universe emerges dynamically from (9+1)D space-time predicted by superstring theory. Here we study a bosonic matrix model obtained by omitting the fermionic matrices. With the adopted simplification and the usage of a large-scale parallel computer, we are able to perform Monte Carlo calculations with matrix size up to N = 512, which is twenty times larger than that used previously for the studies of the original model. When the matrix size is larger than some critical value N c ≃ 110, we find that (3+1)D expanding universe emerges dynamically with a clear large- N scaling property. Furthermore, the observed increase of the spatial extent with time t at sufficiently late times is consistent with a power-law behavior t 1/2, which is reminiscent of the expanding behavior of the Friedmann-Robertson-Walker universe in the radiation dominated era. We discuss possible implications of this result on the original supersymmetric model including fermionic matrices.

Crossing the phantom divide with dissipative normal matter in the Israel-Stewart formalism

NASA Astrophysics Data System (ADS)

Cruz, Norman; Lepe, Samuel

2017-04-01

A phantom solution in the framework of the causal Israel-Stewart (IS) formalism is discussed. We assume a late time behavior of the cosmic evolution by considering only one dominant matter fluid with viscosity. In the model it is assumed a bulk viscosity of the form ξ =ξ0ρ 1 / 2, where ρ is the energy density of the fluid. We evaluate and discuss the behavior of the thermodynamical parameters associated to this solution, like the temperature, rate of entropy, entropy, relaxation time, effective pressure and effective EoS. A discussion about the assumption of near equilibrium of the formalism and the accelerated expansion of the solution is presented. The solution allows to cross the phantom divide without evoking an exotic matter fluid and the effective EoS parameter is always lesser than -1 and time independent. A future singularity (big rip) occurs, but different from the Type I (big rip) solution classified in S. Nojiri, S.D. Odintsov and S. Tsujikawa (2005) [2], if we consider other thermodynamics parameters like, for example, the effective pressure in the presence of viscosity or the relaxation time.

Fatal accidents following changes in daylight savings time: the American experience.

PubMed

Varughese; Allen

2001-01-01

Objective: This study examines specific hypotheses that both sleep loss and behavioral changes occurring with the time shifts for Daylight Savings Time (DST) significantly effect the number of fatal traffic accidents in the United States of America.Background: It has been reported that there is a significant increase in the number of automobile accidents in the spring shift to DST due to the loss of 1 h of sleep. But the extra hour gained at night with the shift from DST in the fall has been variably reported to be associated with increases and decreases in the number of automobile accidents which may reflect either behavioral anticipation with an extended late night prior to the change or the benefit of extra sleep after the change.Methods: Data from 21 years of United States' fatal automobile accidents were gathered. The mean number of accidents on the days at the time of the shifts (Saturday, Sunday and Monday) was compared to the average of the corresponding mean number of accidents on the matching day of the weeks preceding and following the shift. This was repeated for each DST shift. The number of accidents for a particular shift was also correlated with the year of the accidents.Results: There was a significant increase in accidents for the Monday immediately following the spring shift to DST (t=1.92, P=0.034). There was also a significant increase in number of accidents on the Sunday of the fall shift from DST (P<0.002). No significant changes were observed for the other days. A significant negative correlation with the year was found between the number of accidents on the Saturdays and Sundays but not Mondays.Conclusions: The sleep deprivation on the Monday following shift to DST in the spring results in a small increase in fatal accidents. The behavioral adaptation anticipating the longer day on Sunday of the shift from DST in the fall leads to an increased number of accidents suggesting an increase in late night (early Sunday morning) driving when traffic related fatalities are high possibly related to alcohol consumption and driving while sleepy. Public health educators should probably consider issuing warnings both about the effects of sleep loss in the spring shift and possible behaviors such as staying out later, particularly when consuming alcohol in the fall shift. Sleep clinicians should be aware that health consequences from forced changes in the circadian patterns resulting from DST come not only from physiological adjustments but also from behavioral responses to forced circadian changes.

Super-Hubble de Sitter fluctuations and the dynamical RG

NASA Astrophysics Data System (ADS)

Burgess, C. P.; Leblond, L.; Holman, R.; Shandera, S.

2010-03-01

Perturbative corrections to correlation functions for interacting theories in de Sitter spacetime often grow secularly with time, due to the properties of fluctuations on super-Hubble scales. This growth can lead to a breakdown of perturbation theory at late times. We argue that Dynamical Renormalization Group (DRG) techniques provide a convenient framework for interpreting and resumming these secularly growing terms. In the case of a massless scalar field in de Sitter with quartic self-interaction, the resummed result is also less singular in the infrared, in precisely the manner expected if a dynamical mass is generated. We compare this improved infrared behavior with large-N expansions when applicable.

Universality in chaos: Lyapunov spectrum and random matrix theory.

PubMed

Hanada, Masanori; Shimada, Hidehiko; Tezuka, Masaki

2018-02-01

We propose the existence of a new universality in classical chaotic systems when the number of degrees of freedom is large: the statistical property of the Lyapunov spectrum is described by random matrix theory. We demonstrate it by studying the finite-time Lyapunov exponents of the matrix model of a stringy black hole and the mass-deformed models. The massless limit, which has a dual string theory interpretation, is special in that the universal behavior can be seen already at t=0, while in other cases it sets in at late time. The same pattern is demonstrated also in the product of random matrices.

Universality in chaos: Lyapunov spectrum and random matrix theory

NASA Astrophysics Data System (ADS)

Hanada, Masanori; Shimada, Hidehiko; Tezuka, Masaki

2018-02-01

We propose the existence of a new universality in classical chaotic systems when the number of degrees of freedom is large: the statistical property of the Lyapunov spectrum is described by random matrix theory. We demonstrate it by studying the finite-time Lyapunov exponents of the matrix model of a stringy black hole and the mass-deformed models. The massless limit, which has a dual string theory interpretation, is special in that the universal behavior can be seen already at t =0 , while in other cases it sets in at late time. The same pattern is demonstrated also in the product of random matrices.

Chromospheres of late-type active and quiescent dwarfs. III - Variability of CA II H emission profiles

NASA Astrophysics Data System (ADS)

Garcia Lopez, R. J.; Crivellari, L.; Beckman, J. E.; Rebolo, R.

1992-08-01

We have used high-resolution spectra of the Ca II H resonance line in late-type dwarfs, obtained with high S:N ratios, over a period of four years to widen our understanding of the dynamical behavior of the Ca II emission cores. All of the stars dealt with in this article, which are chromospherically active, show variability both in core emission flux and line width. They also show significant wavelength shifts with time of order hundreds of meters per second in the mean core wavelength, and with lower amplitude in the H3 self-absorption, compared to the photospheric rest wavelength of Ca II H. Comparing the emission core shifts with those observed in the H3 features, we find, for the first time, direct prima facie evidence for vertical chromospheric velocity fields, which show stability in sense over periods of years in a given star, with notable modulation in gradient, and which differ in gradient from star to star. We present evidence to show that the observed effects are almost certainly not due to projected rotational modulation, and offer new prospects, given spectral measurements closely sampled in time, for investigating the vertical velocity structures of chromospheres.

Late Pleistocene/Early Holocene Migratory Behavior of Ungulates Using Isotopic Analysis of Tooth Enamel and Its Effects on Forager Mobility.

PubMed

Pilaar Birch, Suzanne E; Miracle, Preston T; Stevens, Rhiannon E; O'Connell, Tamsin C

2016-01-01

Zooarchaeological and paleoecological investigations have traditionally been unable to reconstruct the ethology of herd animals, which likely had a significant influence on the mobility and subsistence strategies of prehistoric humans. In this paper, we reconstruct the migratory behavior of red deer (Cervus elaphus) and caprids at the Pleistocene-Holocene transition in the northeastern Adriatic region using stable oxygen isotope analysis of tooth enamel. The data show a significant change in δ18O values from the Pleistocene into the Holocene, as well as isotopic variation between taxa, the case study sites, and through time. We then discuss the implications of seasonal faunal availability as determining factors in human mobility patterns.

The association between sleep disordered breathing, academic grades, and cognitive and behavioral functioning among overweight subjects during middle to late childhood.

PubMed

Beebe, Dean W; Ris, M Douglas; Kramer, Megan E; Long, Elizabeth; Amin, Raouf

2010-11-01

(1) to determine the associations of sleep disordered breathing (SDB) with behavioral functioning, cognitive test scores, and school grades during middle- to late-childhood, an under-researched developmental period in the SDB literature, and (2) to clarify whether associations between SDB and school grades are mediated by deficits in cognitive or behavioral functioning. cross-sectional correlative study. Office/hospital, plus reported functioning at home and at school. 163 overweight subjects aged 10-16.9 years were divided into 4 groups based upon their obstructive apnea+hypopnea index (AHI) during overnight polysomnography and parent report of snoring: Moderate-Severe OSA (AHI > 5, n = 42), Mild OSA (AHI = 1-5, n = 58), Snorers (AHI < 1 + snoring, n = 26), and No SDB (AHI < 1 and nonsnoring, n = 37). inpatient overnight polysomnography, parent- and self-report of school grades and sleep, parent- and teacher-report of daytime behaviors, and office-based neuropsychological testing. The 4 groups significantly differed in academic grades and parent- and teacher-reported behaviors, particularly inattention and learning problems. These findings remained significant after adjusting for subject sex, race, socioeconomic status, and school night sleep duration. Associations with SDB were confined to reports of behavioral difficulties in real-world situations, and did not extend to office-based neuropsychological tests. Findings from secondary analyses were consistent with, but could not definitively confirm, a causal model in which SDB affects school grades via its impact on behavioral functioning. SDB during middle- to late-childhood is related to important aspects of behavioral functioning, especially inattention and learning difficulties, that may result in significant functional impairment at school.

Behavioral and neurochemical effects of repeated MDMA administration during late adolescence in the rat

PubMed Central

Cox, Brittney M.; Shah, Mrudang M.; Cichon, Teri; Tancer, Manuel E.; Galloway, Matthew P.; Thomas, David M.; Perrine, Shane A.

2015-01-01

Adolescents and young adults disproportionately abuse 3,4-methylenedioxymethamphetamine (MDMA; ‘Ecstasy’); however, since most MDMA research has concentrated on adults, the effects of MDMA on the developing brain remain obscure. Therefore, we evaluated place conditioning to MDMA (or saline) during late adolescence and assessed anxiety-like behavior and monoamine levels during abstinence. Rats were conditioned to associate 5 or 10 mg/kg MDMA or saline with contextual cues over 4 twice-daily sessions. Five days after conditioning, anxiety-like behavior was examined with the open field test and brain tissue was collected to assess serotonin (5-hydroxytryptamine, 5-HT) and its metabolite 5-hydroxyindoleacetic acid (5-HIAA) in the dorsal raphe, amygdala, and hippocampus by high-pressure liquid chromatography (HPLC). In a separate group of rats, anxiety-like and avoidant behaviors were measured using the light–dark box test under similar experimental conditions. MDMA conditioning caused a place aversion at 10, but not at 5, mg/kg, as well as increased anxiety-like behavior in the open field and avoidant behavior in light–dark box test at the same dose. Additionally, 10 mg/kg MDMA decreased 5-HT in the dorsal raphe, increased 5-HT and 5-HIAA in the amygdala, and did not alter levels in the hippocampus. Overall, we show that repeated high (10 mg/kg), but not low (5 mg/kg), dose MDMA during late adolescence in rats increases anxiety-like and avoidant behaviors, accompanied by region-specific alterations in 5-HT levels during abstinence. These results suggest that MDMA causes a region-specific dysregulation of the serotonin system during adolescence that may contribute to maladaptive behavior. PMID:24121061

Theory of mind as a link between oxytocin and maternal behavior.

PubMed

MacKinnon, Anna L; Carter, C Sue; Feeley, Nancy; Gold, Ian; Hayton, Barbara; Santhakumaran, Sangeetha; Zelkowitz, Phyllis

2018-06-01

Oxytocin is a neuropeptide associated with maternal behavior. However the mechanisms underlying this link remain unclear. In a previous study we observed an indirect effect of increased plasma oxytocin during late pregnancy on early postpartum maternal interactive behavior via theory of mind, as assessed by the Reading the Mind in the Eyes Test (RMET). The current study aimed to extend these findings by testing whether this indirect effect would hold longitudinally for maternal behavior at 2-3 years postpartum, as well as for an additional observational measure of maternal mind-mindedness. The original sample of 316 pregnant women (M age  = 31.92 years) was assessed at 12-14 weeks gestation (T1), 32-34 weeks gestation (T2), and 7-9 weeks postpartum (T3). Follow-up measures were taken at 2-3 years postpartum (T4). Mothers' RMET performance (T3) was associated with more structuring and less intrusive maternal behavior at 2-3 years (T4), while their tendency to use mind-related comments (T3) was associated with greater sensitivity (T4). Bootstrap estimates also revealed a significant indirect effect of plasma oxytocin levels during late pregnancy (T2) on maternal structuring and non-intrusive behavior at 2-3 years postpartum (T4) through RMET performance (T3). Results: of the current study confirm and extend the previous findings, demonstrating that theory of mind may represent a social cognitive mechanism linking endogenous oxytocin and maternal behavior. Important changes in the oxytocinergic system during late pregnancy may help prepare for motherhood by promoting the awareness of social cues, which in turn promote maternal behavior from the early postpartum to the early childhood years. Copyright © 2018 Elsevier Ltd. All rights reserved.

Behavioral and neurochemical effects of repeated MDMA administration during late adolescence in the rat.

PubMed

Cox, Brittney M; Shah, Mrudang M; Cichon, Teri; Tancer, Manuel E; Galloway, Matthew P; Thomas, David M; Perrine, Shane A

2014-01-03

Adolescents and young adults disproportionately abuse 3,4-methylenedioxymethamphetamine (MDMA; 'Ecstasy'); however, since most MDMA research has concentrated on adults, the effects of MDMA on the developing brain remain obscure. Therefore, we evaluated place conditioning to MDMA (or saline) during late adolescence and assessed anxiety-like behavior and monoamine levels during abstinence. Rats were conditioned to associate 5 or 10mg/kg MDMA or saline with contextual cues over 4 twice-daily sessions. Five days after conditioning, anxiety-like behavior was examined with the open field test and brain tissue was collected to assess serotonin (5-hydroxytryptamine, 5-HT) and its metabolite 5-hydroxyindoleacetic acid (5-HIAA) in the dorsal raphe, amygdala, and hippocampus by high-pressure liquid chromatography (HPLC). In a separate group of rats, anxiety-like and avoidant behaviors were measured using the light-dark box test under similar experimental conditions. MDMA conditioning caused a place aversion at 10, but not at 5, mg/kg, as well as increased anxiety-like behavior in the open field and avoidant behavior in light-dark box test at the same dose. Additionally, 10mg/kg MDMA decreased 5-HT in the dorsal raphe, increased 5-HT and 5-HIAA in the amygdala, and did not alter levels in the hippocampus. Overall, we show that repeated high (10mg/kg), but not low (5mg/kg), dose MDMA during late adolescence in rats increases anxiety-like and avoidant behaviors, accompanied by region-specific alterations in 5-HT levels during abstinence. These results suggest that MDMA causes a region-specific dysregulation of the serotonin system during adolescence that may contribute to maladaptive behavior. © 2013.

Rheological and micro-Raman time-series characterization of enzyme sol–gel solution toward morphological control of electrospun fibers

PubMed Central

Oriero, Dennis A; Weakley, Andrew T; Aston, D Eric

2012-01-01

Rheological and micro-Raman time-series characterizations were used to investigate the chemical evolutionary changes of silica sol–gel mixtures for electrospinning fibers to immobilize an enzyme (tyrosinase). Results of dynamic rheological measurements agreed with the expected structural transitions associated with reacting sol–gel systems. The electrospinning sols exhibited shear-thinning behavior typical of a power law model. Ultrafine (200–300 nm diameter) fibers were produced at early and late times within the reaction window of approximately one hour from initial mixing of sol solutions with and without enzyme; diameter distributions of these fibers showed much smaller deviations than expected. The enzyme markedly increased magnitudes of both elastic and viscous moduli but had no significant impact on final fiber diameters, suggesting that the shear-thinning behavior of both sol–gel mixtures is dominant in the fiber elongation process. The time course and scale for the electrospinning batch fabrication show strong correlations between the magnitudes in rheological property changes over time and the chemical functional group evolution obtained from micro-Raman time-series analysis of the reacting sol–gel systems. PMID:27877486

Physiological and Behavioral Engagement in Social Contexts as Predictors of Adolescent Depressive Symptoms

PubMed Central

Morgan, Judith K.; Shaw, Daniel S.; Forbes, Erika E.

2013-01-01

Depressive symptoms are considered to have evolutionary social functions to reduce social risks with peers and family members. However, social processes and their relationship to depressive symptoms have been understudied in adolescent boys. Low engagement in social contexts may predict depressive symptoms in adolescent boys, as it may signify efforts to reduce social risks. To address these issues, this study focused on 160 boys at risk for affective problems based on low socioeconomic status. We evaluated how behavioral and physiological engagement in peer and family contexts, respectively, in late childhood predicted depressive symptoms at age 12 and age 15. Social withdrawal was measured across late childhood (ages 9 to 12) in a camp setting using a latent variable of the teacher ratings of withdrawn behavior, peer nominations of withdrawn behavior, and camp counselor ratings of withdrawn behavior. Physiological reactivity was measured during a provocative parent-child conversation using respiratory sinus arrhythmia (RSA) at age 12. Social withdrawal in late childhood predicted depressive symptoms at age 12. The combination of high levels of social withdrawal with peers from ages 9 to 12 and low RSA reactivity with a parent at age 12 predicted higher depressive symptoms at age 15. Withdrawal in multiple social contexts may place boys at risk for depressive symptoms during the vulnerable period of adolescence. PMID:22976840

Developmental estrogen exposures and disruptions to maternal behavior and brain: Effects of ethinyl estradiol, a common positive control.

PubMed

Catanese, Mary C; Vandenberg, Laura N

2017-11-07

Due of its structural similarity to the endogenous estrogen 17β-estradiol (E2), the synthetic estrogen 17α-ethinyl estradiol (EE2) is widely used to study the effects of estrogenic substances on sensitive organs at multiple stages of development. Here, we investigated the effects of EE2 on maternal behavior and the maternal brain in females exposed during gestation and the perinatal period. We assessed several components of maternal behavior including nesting behavior and pup retrieval; characterized the expression of estrogen receptor (ER)α in the medial preoptic area (MPOA), a brain region critical for the display of maternal behavior; and measured expression of tyrosine hydroxylase, a marker for dopaminergic cells, in the ventral tegmental area (VTA), a brain region important in maternal motivation. We found that developmental exposure to EE2 induces subtle effects on several aspects of maternal behavior including time building the nest and time spent engaged in self-care. Developmental exposure to EE2 also altered ERα expression in the central MPOA during both early and late lactation and led to significantly reduced tyrosine hydroxylase immunoreactivity in the VTA. Our results demonstrate both dose- and postpartum stage-related effects of developmental exposure to EE2 on behavior and brain that manifest later in adulthood, during the maternal period. These findings provide further evidence for effects of exposure to exogenous estrogenic compounds during the critical periods of fetal and perinatal development. Copyright © 2017 Elsevier Inc. All rights reserved.

The history of late holocene surface-faulting earthquakes on the central segments of the Wasatch fault zone, Utah

USGS Publications Warehouse

Duross, Christopher; Personius, Stephen; Olig, Susan S; Crone, Anthony J.; Hylland, Michael D.; Lund, William R; Schwartz, David P.

2017-01-01

The Wasatch fault (WFZ)—Utah’s longest and most active normal fault—forms a prominent eastern boundary to the Basin and Range Province in northern Utah. To provide paleoseismic data for a Wasatch Front regional earthquake forecast, we synthesized paleoseismic data to define the timing and displacements of late Holocene surface-faulting earthquakes on the central five segments of the WFZ. Our analysis yields revised histories of large (M ~7) surface-faulting earthquakes on the segments, as well as estimates of earthquake recurrence and vertical slip rate. We constrain the timing of four to six earthquakes on each of the central segments, which together yields a history of at least 24 surface-faulting earthquakes since ~6 ka. Using earthquake data for each segment, inter-event recurrence intervals range from about 0.6 to 2.5 kyr, and have a mean of 1.2 kyr. Mean recurrence, based on closed seismic intervals, is ~1.1–1.3 kyr per segment, and when combined with mean vertical displacements per segment of 1.7–2.6 m, yield mean vertical slip rates of 1.3–2.0 mm/yr per segment. These data refine the late Holocene behavior of the central WFZ; however, a significant source of uncertainty is whether structural complexities that define the segments of the WFZ act as hard barriers to ruptures propagating along the fault. Thus, we evaluate fault rupture models including both single-segment and multi-segment ruptures, and define 3–17-km-wide spatial uncertainties in the segment boundaries. These alternative rupture models and segment-boundary zones honor the WFZ paleoseismic data, take into account the spatial and temporal limitations of paleoseismic data, and allow for complex ruptures such as partial-segment and spillover ruptures. Our data and analyses improve our understanding of the complexities in normal-faulting earthquake behavior and provide geological inputs for regional earthquake-probability and seismic hazard assessments.

Risk and resilience trajectories in war-exposed children across the first decade of life.

PubMed

Halevi, Galit; Djalovski, Amir; Vengrober, Adva; Feldman, Ruth

2016-10-01

Although the effects of early-onset trauma on susceptibility to psychopathology are well-acknowledged, no study to date has followed risk and resilience trajectories in war-exposed young children over lengthy periods and charted predictors of individual pathways. In this prospective longitudinal study, we followed 232 children, including 148 exposed to repeated wartime trauma and 84 controls, at three time points: early childhood (1.5-5 years), middle childhood (5-8 years), and late childhood (9-11 years). Children were diagnosed at each time point and four trajectories defined: children exhibiting no pathology at any time point, those displaying early pathology that later remitted, those showing initial resilience followed by late pathology, and children presenting chronic pathology across the entire first decade. Maternal behavioral containment during trauma evocation and child social engagement during free play were observed in early childhood and maternal emotional distress self-reported across time. War-exposed children showed significantly higher rates of psychopathology, with 81% exhibiting pathology at some point during childhood. In middle childhood, exposed children displayed more posttraumatic stress disorders (PTSD), anxiety disorders, and attention-deficit/hyperactivity disorders (ADHD), and in late childhood more PTSD, conduct/oppositional defiant disorders, and ADHD. War-exposed children had more comorbid psychopathologies and number of comorbidities increased with age. Notably, war-exposure increased prevalence of chronic pathology by 24-fold. Maternal factors, including mother's uncontained style and emotional distress, increased risk for early and chronic psychopathology, whereas reduced child social engagement augmented risk for late pathology. Early-onset chronic stress does not heal naturally, and its effects appear to exacerbate over time, with trauma-exposed children presenting a more comorbid, chronic, and externalizing profile as they grow older. Our findings demonstrate that responses to trauma are dynamic and variable and pinpoint age-specific effects of maternal and child factors on risk and resilience trajectories. Results highlight the importance of conducting long-term follow-up studies and constructing individually tailored early interventions following trauma exposure. © 2016 Association for Child and Adolescent Mental Health.

First description of the breeding biology and natural history of the ochre-breasted brush finch atlapetes semirufus in venezuela

USGS Publications Warehouse

Biancucci, L.; Martin, T.E.

2008-01-01

We provide the first description of the eggs, breeding biology, and natural history of the Ochre-breasted Brush Finch (Atlapetes semirufus). We found 37 nests over four breeding seasons (2004-2007) in Yacamb?? National Park, Venezuela. Nesting activity started in late April and continued until early June suggesting single-brooded behavior despite a typical tropical clutch size of two eggs (x?? = 1.89) that were laid on consecutive days. Egg mass averaged 3.38 g and 11.6% of adult female mass. The incubation and nestling periods averaged 14.9 and 10.5 days, respectively. Only females incubated and the percent time they spent incubating did not change between early and late incubation. Females brooded 42.7% of the time when nestlings were 2 days of age and 20.5% when 9 days of age. Both parents provisioned young at a low rate (3.9 trips/hr) and nestling growth rate (k = 0.45) was also slow. Nest predation rates were relatively high with daily mortality rates of 0.058 and 0.067 during incubation and nestling stages, respectively.

Spectroscopy of the Schwarzschild black hole at arbitrary frequencies.

PubMed

Casals, Marc; Ottewill, Adrian

2012-09-14

Linear field perturbations of a black hole are described by the Green function of the wave equation that they obey. After Fourier decomposing the Green function, its two natural contributions are given by poles (quasinormal modes) and a largely unexplored branch cut in the complex frequency plane. We present new analytic methods for calculating the branch cut on a Schwarzschild black hole for arbitrary values of the frequency. The branch cut yields a power-law tail decay for late times in the response of a black hole to an initial perturbation. We determine explicitly the first three orders in the power-law and show that the branch cut also yields a new logarithmic behavior T(-2ℓ-5)lnT for late times. Before the tail sets in, the quasinormal modes dominate the black hole response. For electromagnetic perturbations, the quasinormal mode frequencies approach the branch cut at large overtone index n. We determine these frequencies up to n(-5/2) and, formally, to arbitrary order. Highly damped quasinormal modes are of particular interest in that they have been linked to quantum properties of black holes.

Comparing postnatal development of gonadal hormones and associated social behaviors in rats, mice, and humans.

PubMed

Bell, Margaret R

2018-05-14

Postnatal development includes dramatic changes in gonadal hormones and the many social behaviors they help regulate, both in rodents and humans. Parental care-seeking is the most salient social interaction in neonates and infants, play and pro-social behaviors are commonly studied in juveniles, and the development of aggression and sexual behavior begins in peripubertal stages but continues through late adolescence into adulthood. While parental behaviors are shown after reproductive success in adulthood, alloparenting behaviors are actually high in juveniles as well. These behaviors are sensitive to both early life organizational effects of gonadal hormones and later life activational regulation. However, changes in circulating gonadal hormones and the display of the above behaviors over development differs between rats, mice and humans. These endpoints are of interest to endocrinologist, toxicologists, neuroscientists because of their relevance to mental health disorders and their vulnerability to effects of endocrine disrupting chemical exposure. As such, the goal of this minireview is to succinctly describe and relate the postnatal development of gonadal hormones and social behaviors to each other, over time and across animal models. Ideally, this will help identify appropriate animal models and age ranges for continued study of both normative development and in contexts of environmental disruption.

Developmental Trajectories of Compensatory Exercise and Fasting Behavior across the Middle School Years

PubMed Central

Davis, Heather A.; Guller, Leila; Smith, Gregory T.

2016-01-01

Compensatory exercise and fasting behavior, in the absence of binge eating and purging, appear to be important eating disorder behaviors that are associated with dysfunction, but little is known about these behaviors in youth. We studied the trajectories of their development in non-binge eating and non-purging girls during early adolescence. Using a longitudinal design, we assessed 564 girls six times over the three years of middle school (grades 6 through 8) and developed trajectories specifying different developmental patterns in relation to the behaviors. Prior to this period, when the girls were in 5th grade (elementary school), we assessed risk factors to predict girls’ subsequent trajectory group membership. Compensatory exercise trajectory groups included a non-engagement group, a group that increased in the behavior, and a group that decreased in the behavior. There were two fasting trajectory groups, one consistently engaging in the behavior and the other consistently not. Elementary school levels of depression, eating expectancies, and thinness expectancies predicted subsequent trajectory group membership. Risk for compensatory exercise and fasting should be evaluated as early as in 5th grade. Targeted interventions should focus on girls in late elementary school or middle school, as this appears to be a critical developmental and maintenance period for compensatory exercise and fasting behavior. PMID:27544806

Prenatal exposure to ethanol during late gestation facilitates operant self-administration of the drug in 5-day-old rats

PubMed Central

Miranda-Morales, Roberto Sebastián; Nizhnikov, Michael E.; Spear, Norman E.

2014-01-01

Prenatal ethanol exposure modifies postnatal affinity to the drug, increasing the probability of ethanol use and abuse. The present study tested developing rats (5-day-old) in a novel operant technique to assess the degree of ethanol self-administration as a result of prenatal exposure to low ethanol doses during late gestation. On a single occasion during each of gestational days 17–20, pregnant rats were intragastrically administered ethanol 1 g/kg, or water (vehicle). On postnatal day 5, pups were tested on a novel operant conditioning procedure in which they learned to touch a sensor to obtain 0.1% saccharin, 3% ethanol, or 5% ethanol. Immediately after a 15-min training session, a 6-min extinction session was given in which operant behavior had no consequence. Pups were positioned on a smooth surface and had access to a touch-sensitive sensor. Physical contact with the sensor activated an infusion pump, which served to deliver an intraoral solution as reinforcement (Paired group). A Yoked control animal evaluated at the same time received the reinforcer when its corresponding Paired pup touched the sensor. Operant behavior to gain access to 3% ethanol was facilitated by prenatal exposure to ethanol during late gestation. In contrast, operant learning reflecting ethanol reinforcement did not occur in control animals prenatally exposed to water only. Similarly, saccharin reinforcement was not affected by prenatal ethanol exposure. These results suggest that in 5-day-old rats, prenatal exposure to a low ethanol dose facilitates operant learning reinforced by intraoral administration of a low-concentration ethanol solution. This emphasizes the importance of intrauterine experiences with ethanol in later susceptibility to drug reinforcement. The present operant conditioning technique represents an alternative tool to assess self-administration and seeking behavior during early stages of development. PMID:24355072

Prenatal exposure to ethanol during late gestation facilitates operant self-administration of the drug in 5-day-old rats.

PubMed

Miranda-Morales, Roberto Sebastián; Nizhnikov, Michael E; Spear, Norman E

2014-02-01

Prenatal ethanol exposure modifies postnatal affinity to the drug, increasing the probability of ethanol use and abuse. The present study tested developing rats (5-day-old) in a novel operant technique to assess the degree of ethanol self-administration as a result of prenatal exposure to low ethanol doses during late gestation. On a single occasion during each of gestational days 17-20, pregnant rats were intragastrically administered ethanol 1 g/kg, or water (vehicle). On postnatal day 5, pups were tested on a novel operant conditioning procedure in which they learned to touch a sensor to obtain 0.1% saccharin, 3% ethanol, or 5% ethanol. Immediately after a 15-min training session, a 6-min extinction session was given in which operant behavior had no consequence. Pups were positioned on a smooth surface and had access to a touch-sensitive sensor. Physical contact with the sensor activated an infusion pump, which served to deliver an intraoral solution as reinforcement (Paired group). A Yoked control animal evaluated at the same time received the reinforcer when its corresponding Paired pup touched the sensor. Operant behavior to gain access to 3% ethanol was facilitated by prenatal exposure to ethanol during late gestation. In contrast, operant learning reflecting ethanol reinforcement did not occur in control animals prenatally exposed to water only. Similarly, saccharin reinforcement was not affected by prenatal ethanol exposure. These results suggest that in 5-day-old rats, prenatal exposure to a low ethanol dose facilitates operant learning reinforced by intraoral administration of a low-concentration ethanol solution. This emphasizes the importance of intrauterine experiences with ethanol in later susceptibility to drug reinforcement. The present operant conditioning technique represents an alternative tool to assess self-administration and seeking behavior during early stages of development. Published by Elsevier Inc.

Applying the model of Goal-Directed Behavior, including descriptive norms, to physical activity intentions: A contribution to improving the Theory of Planned Behavior

USDA-ARS?s Scientific Manuscript database

The theory of planned behavior (TPB) has received its fair share of criticism lately, including calls for it to retire. We contributed to improving the theory by testing extensions such as the model of goal-directed behavior (MGDB, which adds desire and anticipated positive and negative emotions) ap...

Decomposing fear perception: A combination of psychophysics and neurometric modeling of fear perception

PubMed Central

Forscher, Emily C.; Zheng, Yan; Ke, Zijun; Folstein, Jonathan; Li, Wen

2016-01-01

Emotion perception is known to involve multiple operations and waves of analysis, but specific nature of these processes remains poorly understood. Combining psychophysical testing and neurometric analysis of event-related potentials (ERPs) in a fear detection task with parametrically-varied fear intensities (N=45), we sought to elucidate key processes in fear perception. Building on psychophysics marking fear perception thresholds, our neurometric model fitting identified several putative operations and stages: four key processes arose in sequence following face presentation—fear-neutral categorization (P1 at 100 ms), fear detection (P300 at 320 ms), valuation (early subcomponent of the late positive potential/LPP at 400–500 ms) and conscious awareness (late subcomponent LPP at 500–600 ms). Furthermore, within-subject brain-behavior association suggests that initial emotion categorization was mandatory and detached from behavior whereas valuation and conscious awareness directly impacted behavioral outcome (explaining 17% and 31% of the total variance, respectively). The current study thus reveals the chronometry of fear perception, ascribing psychological meaning to distinct underlying processes. The combination of early categorization and late valuation of fear reconciles conflicting (categorical versus dimensional) emotion accounts, lending support to a hybrid model. Importantly, future research could specifically interrogate these psychological processes in various behaviors and psychopathologies (e.g., anxiety and depression). PMID:27546075

Bianchi type string cosmological models in f(R,T) gravity

NASA Astrophysics Data System (ADS)

Sahoo, P. K.; Mishra, B.; Sahoo, Parbati; Pacif, S. K. J.

2016-09-01

In this work we have studied Bianchi-III and - VI 0 cosmological models with string fluid source in f( R, T) gravity (T. Harko et al., Phys. Rev. D 84, 024020 (2011)), where R is the Ricci scalar and T the trace of the stress energy-momentum tensor in the context of late time accelerating expansion of the universe as suggested by the present observations. The exact solutions of the field equations are obtained by using a time-varying deceleration parameter. The universe is anisotropic and free from initial singularity. Our model initially shows acceleration for a certain period of time and then decelerates consequently. Several dynamical and physical behaviors of the model are also discussed in detail.

Toward a comprehensive model of antisocial development: a dynamic systems approach.

PubMed

Granic, Isabela; Patterson, Gerald R

2006-01-01

The purpose of this article is to develop a preliminary comprehensive model of antisocial development based on dynamic systems principles. The model is built on the foundations of behavioral research on coercion theory. First, the authors focus on the principles of multistability, feedback, and nonlinear causality to reconceptualize real-time parent-child and peer processes. Second, they model the mechanisms by which these real-time processes give rise to negative developmental outcomes, which in turn feed back to determine real-time interactions. Third, they examine mechanisms of change and stability in early- and late-onset antisocial trajectories. Finally, novel clinical designs and predictions are introduced. The authors highlight new predictions and present studies that have tested aspects of the model

Changes in Imaging and Cognition in Juvenile Rats After Whole-Brain Irradiation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, Robert J.; Jun, Brandon J.; Advanced Imaging Laboratory, Department of Radiology, Children's Hospital Los Angeles, Los Angeles, California

Purpose: In pediatric cancer survivors treated with whole-brain irradiation (WBI), long-term cognitive deficits and morbidity develop that are poorly understood and for which there is no treatment. We describe similar cognitive defects in juvenile WBI rats and correlate them with alterations in diffusion tensor imaging and magnetic resonance spectroscopy (MRS) during brain development. Methods and Materials: Juvenile Fischer rats received clinically relevant fractionated doses of WBI or a high-dose exposure. Diffusion tensor imaging and MRS were performed at the time of WBI and during the subacute (3-month) and late (6-month) phases, before behavioral testing. Results: Fractional anisotropy in the spleniummore » of the corpus callosum increased steadily over the study period, reflecting brain development. WBI did not alter the subacute response, but thereafter there was no further increase in fractional anisotropy, especially in the high-dose group. Similarly, the ratios of various MRS metabolites to creatine increased over the study period, and in general, the most significant changes after WBI were during the late phase and with the higher dose. The most dramatic changes observed were in glutamine-creatine ratios that failed to increase normally between 3 and 6 months after either radiation dose. WBI did not affect the ambulatory response to novel open field testing in the subacute phase, but locomotor habituation was impaired and anxiety-like behaviors increased. As for cognitive measures, the most dramatic impairments were in novel object recognition late after either dose of WBI. Conclusions: The developing brains of juvenile rats given clinically relevant fractionated doses of WBI show few abnormalities in the subacute phase but marked late cognitive alterations that may be linked with perturbed MRS signals measured in the corpus callosum. This pathomimetic phenotype of clinically relevant cranial irradiation effects may be useful for modeling, mechanistic evaluations, and testing of mitigation approaches.« less

Delayed bedtime due to screen time in schoolchildren: importance of area deprivation.

PubMed

Ogunleye, Ayodele A; Voss, Christine; Sandercock, Gavin R

2015-01-01

Sleep duration is an important predictor of obesity and health. This study evaluated the association between late bedtime and screen time, and the role of geographical deprivation in English schoolchildren. We collected bedtime and waking time, screen time, sociodemographic data and measured body mass index in a cross-section of 1332 11-15-year-old schoolchildren (45.7% female) participating in the East of England healthy heart study. Logistic regression was used to determine the likelihood of late bedtime in schoolchildren with different screen time and from a different geographic location. Mean differences were assessed either on ANOVA or t-test. Approximately 42% of boys went to bed late at night compared with 37% of girls. When compared to those with <2 h of daily screen time, schoolchildren with 2-4 h of screen time were more likely [odds ratio (OR) = 1.50, 95% confidence interval (CI): 1.07-2.09] to go to bed late at night while those with >4 h of daily screen time were most likely to go to sleep late at night (OR, 1.97; 95%CI: 1.34-2.89). Late bedtime was associated with deprivation in schoolchildren. High screen time and deprivation may explain lateness in bedtime in English schoolchildren. This explanation may vary according to area deprivation and geographic location. Family-centered interventions and parental support are important to reduce screen time, late bedtime and increase sleep duration. © 2014 Japan Pediatric Society.

Diurnal Lightning Distributions as Observed by the Optical Transient Detector (OTD) and the Lightning Imaging Sensor (LIS)

NASA Technical Reports Server (NTRS)

Bailey, Jeff C.; Blakeslee, Richard J.; Buechler, Dennis E.; Christian, Hugh J.

2007-01-01

Data obtained from the Optical Transient Detector (April 1995 to March 2000) and the Lightning Imaging Sensor (December 1997 to December 2005) satellites (70 and 35 inclination low earth orbits, respectively) are used to statistically determine the number of flashes in the annual and seasonal diurnal cycle as a function of local and universal time. The data are further subdivided by season, land versus ocean, northern versus southern hemisphere, and other spatial (e.g., continents) and temporal (e.g., time of peak diurnal amplitude) categories. The data include corrections for detection efficiency and instrument view time. Continental results display strong diurnal variation, with a lightning peak in the late afternoon and a minimum in late morning. In regions of the world dominated by large mesoscale convective systems the peak in the diurnal curve shifts toward late evening or early morning hours. The maximum diurnal flash rate occurs in June-August, corresponding to the Northern Hemisphere summer, while the minimum occurs in December-February. Summer lightning dominates over winter activity and springtime lightning dominates over autumn activity at most continental locations. This latter behavior occurs especially strongly over the Amazon region in South America in September-November. Oceanic lightning activity in winter and autumn tends to exceed that in summer and spring. Global lightning is well correlated in phase but not in amplitude with the Carnegie curve. The diurnal flash rate varies about 4-35 percent about the mean, while the Carnegie curve varies around 4-15 percent.

Go Long, Go Deep: Finding Optical Jet Breaks for Swift-Era GRBs with the LBT

NASA Astrophysics Data System (ADS)

Dai, X.; Garnavich, P. M.; Prieto, J. L.; Stanek, K. Z.; Kochanek, C. S.; Bechtold, J.; Bouche, N.; Buschkamp, P.; Diolaiti, E.; Fan, X.; Giallongo, E.; Gredel, R.; Hill, J. M.; Jiang, L.; McClelland, C.; Milne, P.; Pedichini, F.; Pogge, R. W.; Ragazzoni, R.; Rhoads, J.; Smareglia, R.; Thompson, D.; Wagner, R. M.

2008-08-01

Using the 8.4 m Large Binocular Telescope, we observed six GRB afterglows from 2.8 hr to 30.8 days after the burst triggers to systematically probe the late-time behaviors of afterglows including jet breaks, flares, and supernova bumps. We detected five afterglows with Sloan r' magnitudes ranging from 23.0 to 26.3 mag. The depth of our observations allows us to extend the temporal baseline for measuring jet breaks by another decade in timescale. We detected two jet breaks and a third candidate, all of which are not detectable without deep, late-time optical observations. In the other three cases, we do not detect the jet breaks either because of contamination from the host galaxy light, the presence of a supernova bump, or the intrinsic faintness of the optical afterglow. This suggests that the basic picture that GRBs are collimated is still valid and that the apparent lack of Swift jet breaks is due to poorly sampled afterglow light curves, particularly at late times. Based on data acquired using the Large Binocular Telescope (LBT). The LBT is an international collaboration among institutions in the United States, Italy, and Germany. LBT Corporation partners are the University of Arizona on behalf of the Arizona university system; Istituto Nazionale di Astrofisica, Italy; LBT Beteiligungsgesellschaft, Germany, representing the Max Planck Society, the Astrophysical Institute Potsdam, and Heidelberg University; the Ohio State University; and the Research Corporation, on behalf of the University of Notre Dame, the University of Minnesota, and the University of Virginia.

The Association Between Unhealthy Lifestyle Behaviors and the Prevalence of Chronic Kidney Disease (CKD) in Middle-Aged and Older Men.

PubMed

Michishita, Ryoma; Matsuda, Takuro; Kawakami, Shotaro; Kiyonaga, Akira; Tanaka, Hiroaki; Morito, Natsumi; Higaki, Yasuki

2016-07-05

This cross-sectional study evaluated the association between unhealthy lifestyle behaviors and the prevalence of chronic kidney disease (CKD) in middle-aged and older men. The subjects included 445 men without a history of cardiovascular disease, stroke, or dialysis treatment, who were not taking medications. Unhealthy lifestyle behaviors were evaluated using a standardized self-administered questionnaire and were defined as follows: 1) lack of habitual moderate exercise, 2) lack of daily physical activity, 3) slow walking speed, 4) fast eating speed, 5) late-night dinner, 6) bedtime snacking, and 7) skipping breakfast. The participants were divided into four categories, which were classified into quartile distributions based on the number of unhealthy lifestyle behaviors (0-1, 2, 3, and ≥4 unhealthy behaviors). According to a multivariate analysis, the odds ratio (OR) for CKD (defined as estimated glomerular filtration rate [eGFR] <60 mL/min/1.73 m(2) and/or proteinuria) was found to be significantly higher in the ≥4 group than in the 0-1 group (OR 4.67; 95% confidence interval [CI], 1.51-14.40). Moreover, subjects' lack of habitual moderate exercise (OR 3.06; 95% CI, 1.13-8.32) and presence of late-night dinner (OR 2.84; 95% CI, 1.40-5.75) and bedtime snacking behaviors (OR 2.87; 95% CI, 1.27-6.45) were found to be significantly associated with the prevalence of CKD. These results suggest that an accumulation of unhealthy lifestyle behaviors, especially those related to lack of habitual moderate exercise and presence of late-night dinner and bedtime snacking may be associated with the prevalence of CKD.

The Association Between Unhealthy Lifestyle Behaviors and the Prevalence of Chronic Kidney Disease (CKD) in Middle-Aged and Older Men

PubMed Central

Michishita, Ryoma; Matsuda, Takuro; Kawakami, Shotaro; Kiyonaga, Akira; Tanaka, Hiroaki; Morito, Natsumi; Higaki, Yasuki

2016-01-01

Background This cross-sectional study evaluated the association between unhealthy lifestyle behaviors and the prevalence of chronic kidney disease (CKD) in middle-aged and older men. Methods The subjects included 445 men without a history of cardiovascular disease, stroke, or dialysis treatment, who were not taking medications. Unhealthy lifestyle behaviors were evaluated using a standardized self-administered questionnaire and were defined as follows: 1) lack of habitual moderate exercise, 2) lack of daily physical activity, 3) slow walking speed, 4) fast eating speed, 5) late-night dinner, 6) bedtime snacking, and 7) skipping breakfast. The participants were divided into four categories, which were classified into quartile distributions based on the number of unhealthy lifestyle behaviors (0–1, 2, 3, and ≥4 unhealthy behaviors). Results According to a multivariate analysis, the odds ratio (OR) for CKD (defined as estimated glomerular filtration rate [eGFR] <60 mL/min/1.73 m2 and/or proteinuria) was found to be significantly higher in the ≥4 group than in the 0–1 group (OR 4.67; 95% confidence interval [CI], 1.51–14.40). Moreover, subjects’ lack of habitual moderate exercise (OR 3.06; 95% CI, 1.13–8.32) and presence of late-night dinner (OR 2.84; 95% CI, 1.40–5.75) and bedtime snacking behaviors (OR 2.87; 95% CI, 1.27–6.45) were found to be significantly associated with the prevalence of CKD. Conclusions These results suggest that an accumulation of unhealthy lifestyle behaviors, especially those related to lack of habitual moderate exercise and presence of late-night dinner and bedtime snacking may be associated with the prevalence of CKD. PMID:26947951

Childhood and Adolescent Predictors of Late Onset Criminal Careers

ERIC Educational Resources Information Center

Zara, Georgia; Farrington, David P.

2009-01-01

This study explores the emergence of a criminal career in adulthood. The main hypothesis tested is that late criminal onset (at age 21 or later) is influenced by early factors that delay antisocial manifestations. The Cambridge Study in Delinquent Development (CSDD) was used to examine early determinants of criminal behavior. 400 Inner London…

Development of an Attachment-Informed Measure of Sexual Behavior in Late Adolescence

ERIC Educational Resources Information Center

Szielasko, Alicia L.; Symons, Douglas K.; Price, E. Lisa

2013-01-01

There is considerable interest in relations between sexual behavior and romantic attachment styles in adolescence as attachment needs are increasingly met through intimate partners rather than parents. The objectives of this research were to organize a measure of sexual behavior within an attachment theory framework, and then show that this new…

Mechanisms of cognitive control in cadet pilots.

PubMed

Gordon, Shirley; Getter, Nir; Oz, Idit; Garbi, Dror; Todder, Doron

2016-01-01

Optimizing performance of aviators while minimizing risks arising from the exposure to extreme environment, both external and internal, is one of the principles guiding the Israeli Air Force. Young cadets in particular are considered an "at risk" population due to the fact that they have no experience in flight in the first stages of training and are therefore subjects for investigation. In this study, we investigated the cognitive performance of young cadet pilots across different hours of the day. 39 cadets were randomly divided into 3 groups: morning, late afternoon, and late evening groups and then tested on a cognitive battery that contained both simple performance measures but also complex measures like dual-tasking and mental rotation test. The analysis indicated a significant effect of 'time of day' on the participants' accuracy [ F (2, 32) = 3.4, p  < 0.05]. In a post hoc pairwise t-tests, we found a near significant ( p  = 0.52) increase in participants' accuracy and a significant increase [ F (2, 32) = 4.5, p  < 0.05] in participants' reaction time in the late evening group as compared to the morning group. We also found a differential effect of dual tasking on accuracy in the different daytimes [ F (2, 33) = 5.6, p  < 0.01]. In a post hoc analysis, we found that accuracy in the 1-back task deteriorates from single task condition to the dual task condition only in the morning group ( p  < 0.05), but not in the late evening or late-afternoon group. This 'trade-off' behavior, slowing down in order to perform better, in the late evening group may be a result of a voluntary control mechanism (top-down processes) activated at night, in this group. The combination of feeling fatigue, along with the understanding that complex tasks are more resource consuming, caused the cadets to check and double-check before answering, whereas in the morning group, they felt alert and vital, and acted more reactively, ended in an impulsive manner that caused to inaccurate performance.

Gestational stress induces persistent depressive-like behavior and structural modifications within the postpartum nucleus accumbens

PubMed Central

Haim, Achikam; Sherer, Morgan; Leuner, Benedetta

2015-01-01

Postpartum depression (PPD) is a common complication following childbirth experienced by one in every five new mothers. Pregnancy stress enhances vulnerability to PPD and has also been shown to increase depressive-like behavior in postpartum rats. Thus, gestational stress may be an important translational risk factor that can be used to investigate the neurobiological mechanisms underlying PPD. Here we examined the effects of gestational stress on depressive-like behavior during the early/mid and late postpartum periods and evaluated whether this was accompanied by altered structural plasticity in the nucleus accumbens (NAc), a brain region that has been linked to PPD. We show that early/mid (PD8) postpartum female rats exhibited more depressive-like behavior in the forced swim test as compared to late postpartum females (PD22). However, two weeks of restraint stress during pregnancy increased depressive-like behavior regardless of postpartum timepoint. In addition, dendritic length, branching, and spine density on medium spiny neurons in the NAc shell were diminished in postpartum rats that experienced gestational stress although stress-induced reductions in spine density were evident only in early/mid postpartum females. In the NAc core, structural plasticity was not affected by gestational stress but late postpartum females exhibited lower spine density and reduced dendritic length. Overall, these data not only demonstrate structural changes in the NAc across the postpartum period, they also show that postpartum depressive-like behavior following exposure to gestational stress is associated with compromised structural plasticity in the NAc and thus may provide insight into the neural changes that could contribute to PPD. PMID:25359225

Effects of incomplete mixing on reactive transport in flows through heterogeneous porous media

NASA Astrophysics Data System (ADS)

Wright, Elise E.; Richter, David H.; Bolster, Diogo

2017-11-01

The phenomenon of incomplete mixing reduces bulk effective reaction rates in reactive transport. Many existing models do not account for these effects, resulting in the overestimation of reaction rates in laboratory and field settings. To date, most studies on incomplete mixing have focused on diffusive systems; here, we extend these to explore the role that flow heterogeneity has on incomplete mixing. To do this, we examine reactive transport using a Lagrangian reactive particle tracking algorithm in two-dimensional idealized heterogeneous porous media. Contingent on the nondimensional Peclet and Damköhler numbers in the system, it was found that near well-mixed behavior could be observed at late times in the heterogeneous flow field simulations. We look at three common flow deformation metrics that describe the enhancement of mixing in the flow due to velocity gradients: the Okubo-Weiss parameter (θ ), the largest eigenvalue of the Cauchy-Green strain tensor (λC), and the finite-time Lyapunov exponent (Λ ). Strong mixing regions in the heterogeneous flow field identified by these metrics were found to correspond to regions with higher numbers of reactions, but the infrequency of these regions compared to the large numbers of reactions occurring elsewhere in the domain imply that these strong mixing regions are insufficient in explaining the observed near well-mixed behavior. Since it was found that reactive transport in these heterogeneous flows could overcome the effects of incomplete mixing, we also search for a closure for the mean concentration. The conservative quantity u2¯, where u =CA-CB , was found to predict the late time scaling of the mean concentration, i.e., Ci¯˜u2¯ .

Trajectories of postsurgical pain in children: risk factors and impact of late pain recovery on long-term health outcomes after major surgery.

PubMed

Rabbitts, Jennifer A; Zhou, Chuan; Groenewald, Cornelius B; Durkin, Lindsay; Palermo, Tonya M

2015-11-01

Over 1 million children undergo inpatient surgery annually in the United States. Emerging research indicates that many children have longer-term problems with pain. However, limited data exist on the course of pain over time and the impact of pain recovery on long-term health outcomes. We sought to prospectively characterize children's postsurgical pain trajectories using repeated assessments over 12 months. In addition, we identified presurgical child and parent psychological risk factors associated with persistent pain and examined relationships between pain trajectories and long-term health outcomes. Sixty children aged 10 to 18 years undergoing major surgery and their parent/guardian were enrolled. Participants completed assessments at 5 time points: presurgery, inhospital, 2 weeks, 4 months, and 1 year postsurgery. Child and parent pain catastrophizing was assessed during the week before surgery. Children completed daily monitoring with an electronic pain diary and reported on pain characteristics, health-related quality of life, and activity limitations. Group-based longitudinal modeling revealed 2 distinct trajectories of postsurgical pain: early recovery (n = 49, 82%) and late recovery (n = 11, 18%). In a logistic regression model controlling for age and sex, parental pain catastrophizing before surgery significantly predicted membership in the late recovery group (odds ratio = 1.11, P = 0.03), whereas child catastrophizing and baseline pain did not (Ps < 0.05). In a multivariate regression controlling for age and sex, late pain recovery was significantly associated with poorer health-related quality of life (β = -10.7, P = 0.02) and greater activity limitations (β = 3.6, P = 0.04) at 1 year. Our findings suggest that preoperative interventions that modify parent behaviors and cognitions might be beneficial in this population.

Late Holocene spatio-temporal variability of the south Greenland Ice Sheet and adjacent mountain glaciers

NASA Astrophysics Data System (ADS)

Sinclair, G.; Carlson, A. E.; Rood, D. H.; Axford, Y.

2017-12-01

The late Holocene, with its spatially complex pattern of centennial-scale climate variation, is an ideal time period to test the response of the cryosphere to atmospheric and oceanic temperature changes. The south Greenland Ice Sheet (sGrIS), with its proximity to areas of North Atlantic Deep Water formation and a large spectrum of glaciological regimes over a relatively small area, provides an excellent location to examine the spatial heterogeneity of ice-sheet and glacier responses to climate change. Here, we will present 50 Be-10 surface exposure ages from eight moraines in six locations around the margin of the sGrIS. These moraines are located just outboard of historical moraines, and will therefore allow us to constrain the timing of the most extensive prehistoric late-Holocene advance and retreat of ice margins draining the sGrIS and independent valley glaciers. The dataset includes both marine- and land-terminating glaciers draining the sGrIS, the low-altitude Qassimiut lobe, the high-altitude alpine Julianhåb ice cap and isolated valley glaciers. This diverse dataset will allow us to determine to what extent late-Holocene centennial-scale behavior of the ice-sheet and glacier margins were synchronous, perhaps in response to an external climate forcing, or more stochastic, governed instead by local factors such as basal thermal regime, bedrock topography, or microclimates. This has implications for understanding the forcings and responses of cryospheric changes at timescales relevant to human society. In addition to providing context for paleoclimatic and glacial geologic investigations, this work will inform future sea-level projections by providing targets for validating high-resolution ice-sheet and glacier models.

Differentiating location- and distance-based processes in memory for time: an ERP study.

PubMed

Curran, Tim; Friedman, William J

2003-09-01

Memory for the time of events may benefit from reconstructive, location-based, and distance-based processes, but these processes are difficult to dissociate with behavioral methods. Neuropsychological research has emphasized the contribution of prefrontal brain mechanisms to memory for time but has not clearly differentiated location- from distance-based processing. The present experiment recorded event-related brain potentials (ERPs) while subjects completed two different temporal memory tests, designed to emphasize either location- or distance-based processing. The subjects' reports of location-based versus distance-based strategies and the reaction time pattern validated our experimental manipulation. Late (800-1,800 msec) frontal ERP effects were related to location-based processing. The results provide support for a two-process theory of memory for time and suggest that frontal memory mechanisms are specifically related to reconstructive, location-based processing.

Developmental Trajectories of Cigarette Smoking from Adolescence to the Early Thirties: Personality and Behavioral Risk Factors

PubMed Central

Brook, David W.; Brook, Judith S.; Zhang, Chenshu; Whiteman, Martin; Cohen, Patricia; Finch, Stephen J.

2013-01-01

The purpose of this study was to identify distinct trajectories of cigarette smoking from ages 14 to 32, and to examine adolescent personality factors that distinguish trajectories of smoking behavior. Participants (N=975) were randomly selected and followed prospectively since 1975. Follow-up data on cigarette use and personality and behavioral attributes were collected at five points in time, using structured interviews given in private by trained interviewers. Of these subjects, 746 comprised the cohort used in this study. Growth mixture modeling identified five smoking trajectory groups: nonsmokers, occasional smokers, late starters, quitters, and heavy/continuous smokers. Adolescent personality and behavioral risk factors such as lower ego integration, more externalizing behavior, and lower educational aspirations distinguished the trajectory groups. No gender differences were noted. The findings supported the hypotheses indicating multiple distinct trajectory groups of smoking behavior. Smoking behavior appeared in early adolescence and most often continued into adulthood. Emotional difficulties (i.e., lower ego integration), externalizing behavior, and lower educational aspirations in early adolescence were associated both with smoking at an early age and with continuing to smoke into the thirties. To be more effective, smoking prevention programs should target personality and behavioral variations, before smoking becomes habitual, particularly focused on characteristics reflecting behavioral problems as manifested in emotional difficulties, externalizing behavior, and low educational aspirations in early adolescence. The implications for research, prevention, and treatment are discussed. PMID:18686175

Female Wistar rats tested during late proestrus or during pregnancy and ovariectomized rats tested after receiving progesterone or allopregnanolone displayed reduced conflict behavior.

PubMed

Molina-Hernandez, Miguel; Perez, Julian Garcia; Olivera Lopez, Jorge Ivan

2002-06-01

In a conflict test based on the rat's choice between an immediate punished reinforcer or a delayed nonpunished reinforcer, anxiolytic drugs increase the number of immediate punished reinforcers. In this study, two hypotheses were tested: first, during late proestrus or during midpregnancy, female rats will display an elevated amount of immediate punished reinforcers; second, ovariectomized rats will display an elevated amount of immediate punished reinforcers when they receive anxiolytic doses of neurosteroids. Thus, female rats (n = 15) were tested repeatedly during late proestrus, diestrus, and pregnancy in the aforementioned conflict task. They displayed an elevated amount of immediate punished reinforcers during late proestrus (P < .05) and during the 14th (P < .05) and 17th (P < .05) days of pregnancy compared to diestrus or 3rd, 7th, or 20th days of pregnancy. Likewise, ovariectomized rats (n = 90) displayed an elevated amount of immediate punished reinforcers compared to control rats only when they received anxiolytic doses of progesterone (1.0-2.0 mg/kg, P < .05) or allopregnanolone (1.0-2.0 mg/kg, P < .05). In conclusion, female rats displayed reduced conflict behavior during late proestrus and pregnancy, or after received anxiolytic doses of neurosteroids.

Length of home hospice care, family-perceived timing of referrals, perceived quality of care, and quality of death and dying in terminally ill cancer patients who died at home.

PubMed

Yamagishi, Akemi; Morita, Tatsuya; Kawagoe, Shohei; Shimizu, Megumi; Ozawa, Taketoshi; An, Emi; Kobayakawa, Makoto; Tsuneto, Satoru; Shima, Yasuo; Miyashita, Mitsunori

2015-02-01

This study aims to clarify the length of home hospice care, family-perceived timing of referrals, and their effects on the family-perceived quality of care and quality of death and dying of terminally ill cancer patients who died at home and identify the determinants of perceived late referrals. A multicenter questionnaire survey was conducted involving 1,052 family members of cancer patients who died at home supported by 15 home-based hospice services throughout Japan. A total of 693 responses were analyzed (effective response rate, 66 %). Patients received home-based hospice care for a median of 35.0 days, and 8.0 % received home hospice care for less than 1 week. While 1.5 % of the families reported the timing of referrals as early, 42 % reported the timing as late or too late. The families of patients with a length of care of less than 4 weeks were more likely to regard the timing of referrals as late or too late. The patients of family members who regarded the timing of referrals as late or too late had a significantly lower perceived quality of care (effect size, 0.18; P = 0.039) and lower quality of death and dying (effect size, 0.15, P = 0.063). Independent determinants of higher likelihoods of perceived late referrals included: frequent visits to emergency departments, patient being unprepared for worsening condition, and patient having concerns about relationship with new doctor. Discharge nurse availability was independently associated with lower likelihoods of perceived late referrals. A significant number of bereaved families regarded the timing of referrals to home hospices as late, and the perceived timing was associated with the family-perceived quality of care and quality of death and dying. Systematic strategies to overcome the barriers related to perceived late referrals are necessary.

Time and Frequency Dependent Behavior of a Two Dimensional Electron Gas at Long Wavelengths.

DTIC Science & Technology

1985-11-05

lated by techniques which are basically similar to those employed 5-10 T y c e sfor the three dimensional case. The dynamic properties have also received...2m, Vk 2re 2/k, where m and e are, respectively, the electron mass and charge, 1 = . Our system is imposed under an external perturbing potential of...the following form: H = 3’ Pk(t) Pk e i’t (2) where -. is the Fourier comp6nent of the external electric field sufficiently small as to permit the use

Prokineticin receptor 2 (Prokr2) is essential for the regulation of circadian behavior by the suprachiasmatic nuclei.

PubMed

Prosser, Haydn M; Bradley, Allan; Chesham, Johanna E; Ebling, Francis J P; Hastings, Michael H; Maywood, Elizabeth S

2007-01-09

The suprachiasmatic nucleus (SCN), the brain's principal circadian pacemaker, coordinates adaptive daily cycles of behavior and physiology, including the rhythm of sleep and wakefulness. The cellular mechanism sustaining SCN circadian timing is well characterized, but the neurochemical pathways by which SCN neurons coordinate circadian behaviors remain unknown. SCN transplant studies suggest a role for (unidentified) secreted factors, and one potential candidate is the SCN neuropeptide prokineticin 2 (Prok2). Prok2 and its cognate prokineticin receptor 2 (Prokr2/Gpcr73l1) are widely expressed in both the SCN and its neural targets, and Prok2 is light-regulated. Hence, they may contribute to cellular timing within the SCN, entrainment of the clock, and/or they may mediate circadian output. We show that a targeted null mutation of Prokr2 disrupts circadian coordination of the activity cycle and thermoregulation. Specifically, mice lacking Prokr2 lost precision in timing the onset of nocturnal locomotor activity; and under both a light/dark cycle and continuous darkness, there was a pronounced temporal redistribution of activity away from early to late circadian night. Moreover, the coherence of circadian behavior was significantly reduced, and nocturnal body temperature was depressed. Entrainment by light is not, however, dependent on Prokr2, and bioluminescence real-time imaging of organotypical SCN slices showed that the mutant SCN is fully competent as a circadian oscillator. We conclude that Prokr2 is not necessary for SCN cellular timekeeping or entrainment, but it is an essential link for coordination of circadian behavior and physiology by the SCN, especially in defining the onset and maintenance of circadian night.

Sleep Deprivation and Caffeine Treatment Potentiate Photic Resetting of the Master Circadian Clock in a Diurnal Rodent.

PubMed

Jha, Pawan Kumar; Bouâouda, Hanan; Gourmelen, Sylviane; Dumont, Stephanie; Fuchs, Fanny; Goumon, Yannick; Bourgin, Patrice; Kalsbeek, Andries; Challet, Etienne

2017-04-19

Circadian rhythms in nocturnal and diurnal mammals are primarily synchronized to local time by the light/dark cycle. However, nonphotic factors, such as behavioral arousal and metabolic cues, can also phase shift the master clock in the suprachiasmatic nuclei (SCNs) and/or reduce the synchronizing effects of light in nocturnal rodents. In diurnal rodents, the role of arousal or insufficient sleep in these functions is still poorly understood. In the present study, diurnal Sudanian grass rats, Arvicanthis ansorgei , were aroused at night by sleep deprivation (gentle handling) or caffeine treatment that both prevented sleep. Phase shifts of locomotor activity were analyzed in grass rats transferred from a light/dark cycle to constant darkness and aroused in early night or late night. Early night, but not late night, sleep deprivation induced a significant phase shift. Caffeine on its own induced no phase shifts. Both sleep deprivation and caffeine treatment potentiated light-induced phase delays and phase advances in response to a 30 min light pulse, respectively. Sleep deprivation in early night, but not late night, potentiated light-induced c-Fos expression in the ventral SCN. Caffeine treatment in midnight triggered c-Fos expression in dorsal SCN. Both sleep deprivation and caffeine treatment potentiated light-induced c-Fos expression in calbindin-containing cells of the ventral SCN in early and late night. These findings indicate that, in contrast to nocturnal rodents, behavioral arousal induced either by sleep deprivation or caffeine during the sleeping period potentiates light resetting of the master circadian clock in diurnal rodents, and activation of calbindin-containing suprachiasmatic cells may be involved in this effect. SIGNIFICANCE STATEMENT Arousing stimuli have the ability to regulate circadian rhythms in mammals. Behavioral arousal in the sleeping period phase shifts the master clock in the suprachiasmatic nuclei and/or slows down the photic entrainment in nocturnal animals. How these stimuli act in diurnal species remains to be established. Our study in a diurnal rodent, the Grass rat, indicates that sleep deprivation in the early rest period induces phase delays of circadian locomotor activity rhythm. Contrary to nocturnal rodents, both sleep deprivation and caffeine-induced arousal potentiate the photic entrainment in a diurnal rodent. Such enhanced light-induced circadian responses could be relevant for developing chronotherapeutic strategies. Copyright © 2017 the authors 0270-6474/17/374343-16$15.00/0.

Interactions between empathy and resting heart rate in early adolescence predict violent behavior in late adolescence and early adulthood.

PubMed

Galán, Chardée A; Choe, Daniel Ewon; Forbes, Erika E; Shaw, Daniel S

2017-12-01

Although resting heart rate (RHR) and empathy are independently and negatively associated with violent behavior, relatively little is known about the interplay between these psychophysiological and temperament-related risk factors. Using a sample of 160 low-income, racially diverse men followed prospectively from infancy through early adulthood, this study examined whether RHR and empathy during early adolescence independently and interactively predict violent behavior and related correlates in late adolescence and early adulthood. Controlling for child ethnicity, family income, and child antisocial behavior at age 12, empathy inversely predicted moral disengagement and juvenile petitions for violent crimes, while RHR was unrelated to all measures of violent behavior. Interactive effects were also evident such that among men with lower but not higher levels of RHR, lower empathy predicted increased violent behavior, as indexed by juvenile arrests for violent offenses, peer-reported violent behavior at age 17, self-reported moral disengagement at age 17, and self-reported violent behavior at age 20. Implications for prevention and intervention are considered. Specifically, targeting empathic skills among individuals at risk for violent behavior because of specific psychophysiological profiles may lead to more impactful interventions. © 2017 Association for Child and Adolescent Mental Health.

Behavior Problems and Psychiatric Diagnoses in Girls with Gender Identity Disorder: A Follow-Up Study.

PubMed

Drummond, Kelley D; Bradley, Susan J; Peterson-Badali, Michele; VanderLaan, Doug P; Zucker, Kenneth J

2018-02-17

This study evaluated the presence of clinical range behavior problems and psychiatric diagnoses in 25 girls referred for gender identity disorder (GID) in childhood (mean age: 8.88 years) at the time of follow-up in adolescence or adulthood (mean age: 23.2 years). At follow-up, three (12%) of the girls were judged to have persistent GID based on DSM-IV criteria. With regard to behavior problems at follow-up, 39.1% of the girls had a clinical range score on either the Child Behavior Checklist or Adult Behavior Checklist as rated by their mothers, and 33.3% had a clinical range score on either the Youth Self-Report or the Adult Self-Report. On either the Diagnostic Interview for Children and Adolescents or the Diagnostic Interview Schedule, the girls had, on average, 2.67 diagnoses (range: 0-10); 46% met criteria for three or more diagnoses. From the childhood assessment, five variables were significantly associated with a composite Psychopathology Index (PI) at follow-up: a lower IQ, living in a non-two-parent or reconstituted family, a composite behavior problem index, and poor peer relations. At follow-up, degree of concurrent homoeroticism and a composite index of gender dysphoria were both associated with the composite PI. Girls with GID show a psychiatric vulnerability at the time of follow-up in late adolescence or adulthood, although there was considerable variation in their general well-being.

Pathways from childhood intelligence and socioeconomic status to late-life cardiovascular disease risk.

PubMed

Hagger-Johnson, Gareth; Mõttus, René; Craig, Leone C A; Starr, John M; Deary, Ian J

2012-07-01

C-reactive protein (CRP) is an acute-phase marker of systemic inflammation and considered an established risk marker for cardiovascular disease (CVD) in old age. Previous studies have suggested that low childhood intelligence, lower socioeconomic status (SES) in childhood or in later life, unhealthy behaviors, poor wellbeing, and high body mass index (BMI) are associated with inflammation. Life course models that simultaneously incorporate all these risk factors can explain how CVD risks accumulate over time, from childhood to old age. Using the data from 1,091 Scottish adults (Lothian Birth Cohort Study, 1936), a path model was constructed to predict CRP at age 70 from concurrent health behaviors, self-perceived quality of life, and BMI and adulthood SES as mediating variables, and from parental SES and childhood intelligence as distal risk factors. A well-fitting path model (CFI = .92, SRMR = .05) demonstrated significant indirect effects from childhood intelligence and parental social class to inflammation via BMI, health behaviors and quality of life (all ps < .05). Low childhood intelligence, unhealthy behaviors, and higher BMI were also direct predictors of CRP. The life course model illustrated how CVD risks may accumulate over time, beginning in childhood and being both direct and transmitted indirectly via low adult SES, unhealthy behaviors, impaired quality of life, and high BMI. Knowledge on the childhood risk factors and their pathways to poor health can be used to identify high-risk individuals for more intensive and tailored behavior change interventions, and to develop effective public health policies.

Examining the Pathologic Adaptation Model of Community Violence Exposure in Male Adolescents of Color

PubMed Central

Gaylord-Harden, Noni K.; So, Suzanna; Bai, Grace J.; Henry, David B.; Tolan, Patrick H.

2017-01-01

The current study examined a model of desensitization to community violence exposure—the pathologic adaptation model—in male adolescents of color. The current study included 285 African American (61%) and Latino (39%) male adolescents (W1 M age = 12.41) from the Chicago Youth Development Study to examine the longitudinal associations between community violence exposure, depressive symptoms, and violent behavior. Consistent with the pathologic adaptation model, results indicated a linear, positive association between community violence exposure in middle adolescence and violent behavior in late adolescence, as well as a curvilinear association between community violence exposure in middle adolescence and depressive symptoms in late adolescence, suggesting emotional desensitization. Further, these effects were specific to cognitive-affective symptoms of depression and not somatic symptoms. Emotional desensitization outcomes, as assessed by depressive symptoms, can occur in male adolescents of color exposed to community violence and these effects extend from middle adolescence to late adolescence. PMID:27653968

Chemical Evidence for Evolution of galaxies

NASA Astrophysics Data System (ADS)

Dutil, Yvan

I have compiled the very best data published on abundance gradients. From this sample of 29 galaxies, some information can be gained on the mecanism of morphological evolution in disk galaxies. From this sample, I find that early-type galaxies show an identical trend in the behavior of extrapolated central abundance versus morphological type to that shown by late-type galaxies with strong bars, even in the absence of bar! On a a diagram showing extrapolated central abundance versus morphological type, two sequences appear: late-type barred galaxies and early-type galaxies (barred or not barred) fall on sequence 0.5 dex below that of normal late-type galaxies. This behavior is consistent with a scenario of morphological evolution of disk galaxies by formation and dissolution of a bar over a period of a few 10^^9 yr, where later type galaxies (Sd,Sc,Sbc, evolve into earlier-type disk galaxies trough transitory SBc and SBb phases.

Sex roles and mutual mate choice matter during mate sampling.

PubMed

Myhre, Lise Cats; de Jong, Karen; Forsgren, Elisabet; Amundsen, Trond

2012-06-01

The roles of females and males in mating competition and mate choice have lately proven more variable, between and within species, than previously thought. In nature, mating competition occurs during mate search and is expected to be regulated by the numbers of potential mates and same-sex competitors. Here, we present the first study to test how a temporal change in sex roles affects mating competition and mate choice during mate sampling. Our model system (the marine fish Gobiusculus flavescens) is uniquely suitable because of its change in sex roles, from conventional to reversed, over the breeding season. As predicted from sex role theory, courtship was typically initiated by males and terminated by females early in the breeding season. The opposite pattern was observed late in the season, at which time several females often simultaneously courted the same male. Mate-searching females visited more males early than late in the breeding season. Our study shows that mutual mate choice and mating competition can have profound effects on female and male behavior. Future work needs to consider the dynamic nature of mating competition and mate choice if we aim to fully understand sexual selection in the wild.

Emotion regulation in social anxiety disorder: behavioral and neural responses to three socio-emotional tasks

PubMed Central

2013-01-01

Background Social anxiety disorder (SAD) is thought to involve deficits in emotion regulation, and more specifically, deficits in cognitive reappraisal. However, evidence for such deficits is mixed. Methods Using functional magnetic resonance imaging (fMRI) of blood oxygen-level dependent (BOLD) signal, we examined reappraisal-related behavioral and neural responses in 27 participants with generalized SAD and 27 healthy controls (HC) during three socio-emotional tasks: (1) looming harsh faces (Faces); (2) videotaped actors delivering social criticism (Criticism); and (3) written autobiographical negative self-beliefs (Beliefs). Results Behaviorally, compared to HC, participants with SAD had lesser reappraisal-related reduction in negative emotion in the Beliefs task. Neurally, compared to HC, participants with SAD had lesser BOLD responses in reappraisal-related brain regions when reappraising faces, in visual and attention related regions when reappraising criticism, and in the left superior temporal gyrus when reappraising beliefs. Examination of the temporal dynamics of BOLD responses revealed late reappraisal-related increased responses in HC, compared to SAD. In addition, the dorsomedial prefrontal cortex (DMPFC), which showed reappraisal-related increased activity in both groups, had similar temporal dynamics in SAD and HC during the Faces and Criticism tasks, but greater late response increases in HC, compared to SAD, during the Beliefs task. Reappraisal-related greater late DMPFC responses were associated with greater percent reduction in negative emotion ratings in SAD patients. Conclusions These results suggest a dysfunction of cognitive reappraisal in SAD patients, with overall reduced late brain responses in prefrontal regions, particularly when reappraising faces. Decreased late activity in the DMPFC might be associated with deficient reappraisal and greater negative reactivity. Trial registration ClinicalTrials.gov identifier: NCT00380731 PMID:24517388

The association between changes in lifestyle behaviors and the incidence of chronic kidney disease (CKD) in middle-aged and older men.

PubMed

Michishita, Ryoma; Matsuda, Takuro; Kawakami, Shotaro; Tanaka, Satoshi; Kiyonaga, Akira; Tanaka, Hiroaki; Morito, Natsumi; Higaki, Yasuki

2017-08-01

This study was designed to evaluate whether changes in lifestyle behaviors are correlated with the incidence of chronic kidney disease (CKD). The subjects consisted of 316 men without a history of cardiovascular disease, stroke, or renal dysfunction or dialysis treatment. The following lifestyle behaviors were evaluated using a standardized self-administered questionnaire: habitual moderate exercise, daily physical activity, walking speed, eating speed, late-night dinner, bedtime snacking, skipping breakfast, and drinking and smoking habits. The subjects were divided into four categories according to the change in each lifestyle behavior from baseline to the end of follow-up (healthy-healthy, unhealthy-healthy, healthy-unhealthy and unhealthy-unhealthy). A multivariate analysis showed that, with respect to habitual moderate exercise and late-night dinner, maintaining an unhealthy lifestyle resulted in a significantly higher odds ratio (OR) for the incidence of CKD than maintaining a lifestyle (OR 8.94; 95% confidence interval [CI], 1.10-15.40 for habitual moderate exercise and OR 4.00; 95% CI, 1.38-11.57 for late-night dinner). In addition, with respect to bedtime snacking, the change from a healthy to an unhealthy lifestyle and maintaining an unhealthy lifestyle resulted in significantly higher OR for incidence of CKD than maintaining a healthy lifestyle (OR 4.44; 95% CI, 1.05-13.93 for healthy-unhealthy group and OR 11.02; 95% CI, 2.83-26.69 for unhealthy-unhealthy group). The results of the present study suggest that the lack of habitual moderate exercise, late-night dinner, and bedtime snacking may increase the risk of CKD. Copyright © 2017 The Authors. Production and hosting by Elsevier B.V. All rights reserved.

On asymptotic behavior of anisotropic branes with induced gravity inspired by L(R) term

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heydari-Fard, Malihe, E-mail: heydarifard@qom.ac.ir

2010-12-01

The DGP brane-world scenario provides the accelerated expansion of the universe at late-time by large-distance modification of general relativity without any need for dark energy. Using the method in reference [33], we investigate the asymptotic behavior of homogeneous and anisotropic cosmologies on a generalization of DGP scenario where the effective theory of gravity induced on the brane is given by a L(R) term. We show that for a constant induced curvature term on the brane all Bianchi models except type IX isotropize, like general relativity, if the effective energy density and E{sub ab} term satisfy some energy conditions. Finally, wemore » compare the result of the model with the result of anisotropic DGP branes and general relativity.« less

A model of motor performance during surface penetration: from physics to voluntary control.

PubMed

Klatzky, Roberta L; Gershon, Pnina; Shivaprabhu, Vikas; Lee, Randy; Wu, Bing; Stetten, George; Swendsen, Robert H

2013-10-01

The act of puncturing a surface with a hand-held tool is a ubiquitous but complex motor behavior that requires precise force control to avoid potentially severe consequences. We present a detailed model of puncture over a time course of approximately 1,000 ms, which is fit to kinematic data from individual punctures, obtained via a simulation with high-fidelity force feedback. The model describes puncture as proceeding from purely physically determined interactions between the surface and tool, through decline of force due to biomechanical viscosity, to cortically mediated voluntary control. When fit to the data, it yields parameters for the inertial mass of the tool/person coupling, time characteristic of force decline, onset of active braking, stopping time and distance, and late oscillatory behavior, all of which the analysis relates to physical variables manipulated in the simulation. While the present data characterize distinct phases of motor performance in a group of healthy young adults, the approach could potentially be extended to quantify the performance of individuals from other populations, e.g., with sensory-motor impairments. Applications to surgical force control devices are also considered.

Global bioevents and the question of periodicity

NASA Astrophysics Data System (ADS)

Sepkoski, J. John

The hypothesis of periodicity in extinction is an empirical claim that extinction events, while variable in magnitude, are regular in timing and therefore are serially dependent upon some single, ultimate cause with clocklike behavior. This hypothesis is controversal, in part because of questions regarding the identity and timing of certain extinction events and because of speculations concerning possible catastrophic extraterrestrial forcing mechanisms. New data on extinctions of marine animal genera are presented that display a high degree of periodicity in the Mesozoic and Cenozoic as well as a suggestion of nonstationary periodicity in the late Paleozoic. However, no periodicity is evident among the as yet poorly documented extinction events of the early and middle Paleozoic.

Multiple determinants controlling activation of yeast replication origins late in S phase.

PubMed

Friedman, K L; Diller, J D; Ferguson, B M; Nyland, S V; Brewer, B J; Fangman, W L

1996-07-01

Analysis of a 131-kb segment of the left arm of yeast chromosome XIV beginning 157 kb from the telomere reveals four highly active origins of replication that initiate replication late in S phase. Previous work has shown that telomeres act as determinants for late origin activation. However, at least two of the chromosome XIV origins maintain their late activation time when located on large circular plasmids, indicating that late replication is independent of telomeres. Analysis of the replication time of plasmid derivatives containing varying amounts of chromosome XIV DNA show that a minimum of three chromosomal elements, distinct from each tested origin, contribute to late activation time. These late determinants are functionally equivalent, because duplication of one set of contributing sequences can compensate for the removal of another set. Furthermore, insertion of an origin that is normally early activated into this domain results in a shift to late activation, suggesting that the chromosome XIV origins are not unique in their ability to respond to the late determinants.

Association of established smoking among adolescents with timing of exposure to smoking depicted in movies.

PubMed

Primack, Brian A; Longacre, Meghan R; Beach, Michael L; Adachi-Mejia, Anna M; Titus, Linda J; Dalton, Madeline A

2012-04-04

It is not known whether exposure to smoking depicted in movies carries greater influence during early or late adolescence. We aimed to quantify the independent relative contribution to established smoking of exposure to smoking depicted in movies during both early and late adolescence. We prospectively assessed 2049 nonsmoking students recruited from 14 randomly selected public schools in New Hampshire and Vermont. At baseline enrollment, students aged 10-14 years completed a written survey to determine personal, family, and sociodemographic characteristics and exposure to depictions of smoking in the movies (early exposure). Seven years later, we conducted follow-up telephone interviews to ascertain follow-up exposure to movie smoking (late exposure) and smoking behavior. We used multiple regression models to assess associations between early and late exposure and development of established smoking. One-sixth (17.3%) of the sample progressed to established smoking. In analyses that controlled for covariates and included early and late exposure in the same model, we found that students in the highest quartile for early exposure had 73% greater risk of established smoking than those in the lowest quartile for early exposure (27.8% vs 8.6%; relative risk for Q4 vs Q1 = 1.73, 95% confidence interval = 1.14 to 2.62). However, late exposure to depictions of smoking in movies was not statistically significantly associated with established smoking (22.1% vs 14.0%; relative risk for Q4 vs Q1 = 1.13, 95% confidence interval = 0.89 to 1.44). Whereas 31.6% of established smoking was attributable to early exposure, only an additional 5.3% was attributable to late exposure. Early exposure to smoking depicted in movies is associated with established smoking among adolescents. Educational and policy-related interventions should focus on minimizing early exposure to smoking depicted in movies.

Association of Established Smoking Among Adolescents With Timing of Exposure to Smoking Depicted in Movies

PubMed Central

Longacre, Meghan R.; Beach, Michael L.; Adachi-Mejia, Anna M.; Titus, Linda J.; Dalton, Madeline A.

2012-01-01

Background It is not known whether exposure to smoking depicted in movies carries greater influence during early or late adolescence. We aimed to quantify the independent relative contribution to established smoking of exposure to smoking depicted in movies during both early and late adolescence. Methods We prospectively assessed 2049 nonsmoking students recruited from 14 randomly selected public schools in New Hampshire and Vermont. At baseline enrollment, students aged 10–14 years completed a written survey to determine personal, family, and sociodemographic characteristics and exposure to depictions of smoking in the movies (early exposure). Seven years later, we conducted follow-up telephone interviews to ascertain follow-up exposure to movie smoking (late exposure) and smoking behavior. We used multiple regression models to assess associations between early and late exposure and development of established smoking. Results One-sixth (17.3%) of the sample progressed to established smoking. In analyses that controlled for covariates and included early and late exposure in the same model, we found that students in the highest quartile for early exposure had 73% greater risk of established smoking than those in the lowest quartile for early exposure (27.8% vs 8.6%; relative risk for Q4 vs Q1 = 1.73, 95% confidence interval = 1.14 to 2.62). However, late exposure to depictions of smoking in movies was not statistically significantly associated with established smoking (22.1% vs 14.0%; relative risk for Q4 vs Q1 = 1.13, 95% confidence interval = 0.89 to 1.44). Whereas 31.6% of established smoking was attributable to early exposure, only an additional 5.3% was attributable to late exposure. Conclusions Early exposure to smoking depicted in movies is associated with established smoking among adolescents. Educational and policy-related interventions should focus on minimizing early exposure to smoking depicted in movies. PMID:22423010

The Social Functions of Antisocial Behavior: Considerations for School Violence Prevention Strategies for Students with Disabilities

ERIC Educational Resources Information Center

Farmer, Thomas W.; Lane, Kathleen L.; Lee, David L.; Hamm, Jill V.; Lambert, Kerrylin

2012-01-01

Research on school social dynamics suggests that antisocial behavior is often supported by peer group processes particularly during late childhood and adolescence. Building from a social interactional framework, this article explores how information on the social functions of aggressive and disruptive behavior may help to guide function-based…

Reinforcement and the Organization of Behavior in Golden Hamsters: Pavlovian Conditioning with Food and Shock Unconditioned Stimuli

ERIC Educational Resources Information Center

Shettleworth, Sara J.

1978-01-01

There has been considerable interest lately in cases where instrumental conditionability appears to depend on the reinforcer used. Here the effects of Pavlovian conditioned stimuli (CSs)on golden hamster behaviors was observed. The intent was to see whether previously reported differences among the behaviors produced by food reinforcement and…

Family Sex Communication and the Sexual Desire, Attitudes, and Behavior of Late Adolescents

ERIC Educational Resources Information Center

Zamboni, Brian D.; Silver, Rachel

2009-01-01

Parental sex education might promote healthy sexual behavior among adolescents, but some parents assume that family communication about sex will lead to sexual activity. Family sex communication has been studied with a limited range of adolescent sexual behaviors but not sexual fantasy or desire. Two measures of family sex communication were…

Alcohol Use and Antisocial Behavior in Late Adolescence: Characteristics of a Sample Attending a GED Program

ERIC Educational Resources Information Center

Owens, Meredith Reesman; Bergman, Andrea

2010-01-01

This study examined peer deviance, disinhibition, and ADHD symptoms as differential predictors of alcohol use, alcohol use disorder symptoms, and antisocial behavior. It was hypothesized that peer deviance would most strongly predict alcohol use while disinhibition and ADHD would predict alcohol use disorder symptoms and antisocial behavior.…

Circadian Rhythms and Second Language Performance

ERIC Educational Resources Information Center

de Bot, Kees; Fang, Fang

2017-01-01

Human behavior is not constant over the hours of the day, and there are considerable individual differences. Some people raise early and go to bed early and have their peek performance early in the day ("larks") while others tend to go to bed late and get up late and have their best performance later in the day ("owls"). In…

[Weak evidence concerning sedentary lifestyle and its association with cardio-metabolic illness among young people. "Junk food" and late evenings in front of the screen part of a complex connection].

PubMed

Fröberg, Andreas; Raustorp, Anders

2015-06-16

During recent decades there has been a rapidly growing interest in youths' sedentary behaviour and its association with cardio-metabolic health. Currently there is little-to-no evidence for a cross-sectional and longitudinal association between volume and pattern (bouts and breaks) of objectively measured sedentary behavior and body weight in youth. Likewise, there is little-to-no evidence for a cross-sectional association between volume and pattern of objectively measured sedentary behavior and other markers for cardio-metabolic risk in youth. However, there is sufficient evidence for a cross-sectional and longitudinal association between screen-time and body weight and blood pressure and blood lipids. Furthermore, there is evidence for a cross-sectional association between youths' screen-time and clustered metabolic risk and insulin resistance. Overall, the level of evidence was low and, therefore, caution is required when interpreting the results.

Ontogeny of cocaine-induced behaviors and cocaine pharmacokinetics in male and female neonatal, preweanling, and adult rats.

PubMed

McDougall, Sanders A; Apodaca, Matthew G; Mohd-Yusof, Alena; Mendez, Adrian D; Katz, Caitlin G; Teran, Angie; Garcia-Carachure, Israel; Quiroz, Anthony T; Crawford, Cynthia A

2018-04-18

Ontogenetic differences in the behavioral responsiveness to cocaine have often been attributed to the maturation of dopaminergic elements (e.g., dopamine transporters, D2 High receptors, receptor coupling, etc.). The purpose of this study was to determine whether ontogenetic changes in cocaine pharmacokinetics might contribute to age-dependent differences in behavioral responsiveness. Male and female neonatal (PD 5), preweanling (PD 10 and PD 20), and adult (PD 70) rats were injected (IP) with cocaine or saline and various behaviors (e.g., locomotor activity, forelimb paddle, vertical activity, head-down sniffing, etc.) were measured for 90 min. In a separate experiment, the dorsal striata of young and adult rats were removed at 10 time points (0-210 min) after IP cocaine administration. Peak cocaine values, cocaine half-life, and dopamine levels were determined using HPLC. When converted to percent of saline controls, PD 5 and PD 10 rats were generally more sensitive to cocaine than older rats, but this effect varied according to the behavior being assessed. Peak cocaine values did not differ according to age or sex, but cocaine half-life in brain was approximately 2 times longer in PD 5 and PD 10 rats than adults. Cocaine pharmacokinetics did not differ between PD 20 and PD 70 rats. Differences in the cocaine-induced behavioral responsiveness of very young rats (PD 5 and PD 10) and adults may be attributable, at least in part, to pharmacokinetic factors; whereas, age-dependent behavioral differences between the late preweanling period and adulthood cannot readily be ascribed to cocaine pharmacokinetics.

Late chronotype and high social jetlag are associated with burnout in evening-shift workers: Assessment using the Chinese-version MCTQshift.

PubMed

Cheng, Wan-Ju; Hang, Liang-Wen

2018-04-16

Chronotypes are associated with shift work tolerance and sleep in shift workers, and sleep mediates the impact of shift work on mental health. However, the role of chronotype in the association between shift work and mental health has not been clarified. In this study, we aimed to examine the association between chronotype and burnout in shift workers, using the validated Munich ChronoType Questionnaire for shift workers (MCTQ shift ). A total of 288 shift workers with irregular shift frequencies were recruited and completed the Chinese-version MCTQ shift and the Morningness-Eveningness Questionnaire (MEQ). Chronotypes were assessed by the calculation of corrected mid-sleep time (MSF SC ) from mid-sleep time on free days (MSF) based on their exact shift schedules. Another 26 evening-shift nurses were monitored with actigraphy for at least two consecutive evening shifts and the following two free days. Burnout was evaluated using the Copenhagen Burnout Inventory. We found that MSF E SC , MSF E and mid-sleep time on workdays (MSW E ) had normal distributions and correlated significantly with MEQ scores (r = - 0.47, -0.45 and -0.47, respectively; all p < 0.001). MSW was more closely correlated with actigraphy-derived mid-sleep time on the free day before workdays than that on workdays (r = 0.61 and 0.48, respectively, p < 0.05). Sleep duration was significantly longer on workdays among evening-shift workers who slept late on workdays than those who slept early (β = 0.59, p < 0.001). After demographic and work characteristics were adjusted for in linear regression models, late chronotype and high social jetlag were associated with burnout scores in evening-shift workers. In conclusion, the Chinese-version MCTQ shift is a valid tool for chronotype assessment. Interventions to improve sleep in shift workers should be tailored to chronotype due to variations in sleep behavior. Late chronotype may be an inherent feature of mental health problems, because the association with burnout was significant in both day workers in previous studies and shift workers.

[A Survey of Maternal Dietary Behavior Based on Theory of Reasoned Action].

PubMed

Huang, Yan; Luo, Bi-ru

2015-05-01

To detect the diet behavior and influencing factors of related behavior at different stages among pregnant women. Based on the Theory of Reasoned Action (TRA), literature review, expert evaluation and preliminary investigation, we designed and finalized three questionnaires. Diet behaviors among women in early term, medium term and late term were investigated by using the questionnaires. 624 early term, 619 medium term and 738 late term valid questionnaires were returned. Participants ranged from 18 to 45 years of age. 74% pregnancy body mass index (BMI) was within the normal range. More than 43% care taking was provided by the mother, followed by the husband. The participants had a good eating behavior on the whole. At 3 stages, carbohydrate intake, protein intake and fat intake were no significant difference when compared with that of recommended value (P> 0. 05). The pregnant women intaked insufficient cereal, beans, dairy and aquatic products, while fruit and nuts were more than needed (P<0. 05). Subjective norms influenced their eating behavior indirectly through influencing their behavior attitude and behavioral intention. The attitude could influence behavior directly without involving the intention. The participants had relatively good diet behavior, but still had problems on food choice and a reasonable combination of a variety of food. Subjective norms influenced their behavior attitude and behavioral intention. The mother had the strongest influence on the pregnant woman's diet attitude and behavioral intention among all those had direct contact with the pregnant woman.

Temperament and Externalizing Behavior as Mediators of Genetic Risk on Adolescent Substance Use

PubMed Central

Trucco, Elisa M.; Hicks, Brian M.; Villafuerte, Sandra; Nigg, Joel; Burmeister, Margit; Zucker, Robert A.

2016-01-01

Understanding how specific genes contribute to risk for addiction remains challenging. This study tests whether childhood temperament and externalizing behavior in early adolescence account for a portion of the association between specific genetic variants and substance use problems in late adolescence. The sample consisted of 487 adolescents from the Michigan Longitudinal Study, a high-risk sample (70.2% male, 81.7% European American ancestry). Polymorphisms across serotonergic (SLC6A4, 5-HTTLPR), dopaminergic (DRD4, u-VNTR), noradrenergic (SLC6A2, rs36021), and GABAergic (GABRA2, rs279858; GABRA6, rs3811995) genes were examined given prior support for associations with temperament, externalizing behavior, and substance use problems. The temperament traits behavioral control and resiliency were assessed using interviewer ratings (ages 9-11), and externalizing behavior (ages 12-14) was assessed using teacher ratings. Self-reported substance use outcomes (ages 15-17) included maximum alcoholic beverages consumed in 24 hours, and frequency of past year cigarette and marijuana use. Behavioral control, resiliency, and externalizing behavior accounted for the associations between polymorphisms in noradrenergic and GABAergic genes and substance use in late adolescence. Individual differences in emotional coping and behavioral regulation represent non-specific neurobiological underpinnings for an externalizing pathway to addiction. PMID:26845260

Aggression Replacement Training and Childhood Trauma

ERIC Educational Resources Information Center

Amendola, A. Mark; Oliver, Robert W.

2013-01-01

Aggression Replacement Training (ART) was developed by the late Arnold Goldstein of Syracuse University to teach positive alternatives to children and youth with emotional and behavioral problems (Glick & Gibbs, 2011; Goldstein, Glick, & Gibbs, 1998). ART provides cognitive, affective, and behavioral interventions to build competence in…

Does Competence Mediate the Associations between Puberty and Internalizing or Externalizing Problems in Adolescent Girls

PubMed Central

Negriff, Sonya; Hillman, Jennifer, B.; Dorn, Lorah D.

2011-01-01

Purpose To examine separate mediational models linking a) menarcheal status or b) pubertal timing to internalizing and externalizing problems through competence. Method Cross-sectional analyses of 262 adolescent girls (11–17 years; M=14.93, SD=2.17) enrolled in a longitudinal study examining the association of psychological functioning and smoking with reproductive and bone health. Measures of menarcheal status (pre/post), pubertal timing (early, on-time, or late), internalizing and externalizing behavior, and perceived competence (parent and adolescent report) were obtained. Structural Equation Modeling was used for analyses. Results Perceived competence was found to fully mediate the association between menarcheal status and parent report of internalizing and externalizing problems. For adolescent report, there was a full mediation effect for internalizing problems but a partial mediation effect for externalizing problems. Being menarcheal was related to lower competence which was related to higher internalizing and externalizing problems. Models including pubertal timing were not significant. Conclusions Perceived competence is important in understanding the associations between menarcheal status and internalizing and externalizing problems. Interventions targeting competence, particularly in post-menarcheal girls, may reduce or prevent problem behaviors. PMID:21939864

Phasic heart rate responses and cardiac cycle time in auditory choice reaction time.

PubMed

van der Molen, M W; Somsen, R J; Orlebeke, J F

1983-01-01

This study investigated the cardiovascular-behavioral interaction under short and long stimulus interval conditions. In addition, the cardiovascular-behavioral interaction was studied as affected by cardiac cycle duration. Fourteen subjects performed a choice reaction time (RT) task employing a mixed speed-accuracy tradeoff design in which reactions were paced to coincide with a signal that occurs randomly at either 200 or 500 msec after the reaction stimulus. The preparatory interval between a warning stimulus and a lead-reaction stimulus complex was also varied (2 vs. 4.5 sec). Anticipatory deceleration occurred within the 4.5 sec interval but not in the 2 sec interval. The depth of anticipatory deceleration did not discriminate between fast and slow reactions; but an earlier shift from deceleration to acceleration was associated with fast reactions. The effect of stimulus timing relative to the R-wave of the electrocardiogram was also analysed. Meaningful stimuli tended to produce cardiac slowing as previously described in the literature. Early occurring stimuli prolong the cycle of their occurrence more than late occurring stimuli. The later prolong the subsequent cycle. Cardiac cycle time effects were absent for unattended stimuli. The results of anticipatory deceleration suggested that the depth of deceleration was regulated by time-uncertainty and speed-accuracy criterion.

Early School Engagement and Late Elementary Outcomes for Maltreated Children in Foster Care

PubMed Central

Pears, Katherine C.; Kim, Hyoun K.; Fisher, Philip A.; Yoerger, Karen

2013-01-01

Children with a history of maltreatment and placement into foster care face elevated risks of poor psychosocial outcomes including school failure, substance use, externalizing and deviant peer association. For children in the general population, school engagement appears to be a promotive factor in preventing negative outcomes. In this study, differences in behavioral, affective, and cognitive dimensions of school engagement in early elementary school were explored in maltreated children in foster care (n = 93) and a community comparison group of low SES, non-maltreated children (n = 54). It was also hypothesized that the three dimensions of school engagement would mediate the association between being maltreated and in foster care and several outcomes in late elementary school (Grades 3 to 5): academic competence, endorsement of substance use, externalizing behaviors, and deviant peer association. Measures were multi-method and multi-informant. Results showed that the children in foster care had lower affective and cognitive school engagement than children in the community comparison group. Structural equation modeling revealed that both affective and cognitive school engagement mediated the association between group status and academic competence in late elementary school. Cognitive engagement also mediated the association between group status and engagement in risk behaviors. The identification of dimensions of early school engagement that predict later outcomes suggests potential points of intervention to change trajectories of academic and behavioral adjustment for maltreated children in foster care. PMID:23477532

Decomposing fear perception: A combination of psychophysics and neurometric modeling of fear perception.

PubMed

Forscher, Emily C; Zheng, Yan; Ke, Zijun; Folstein, Jonathan; Li, Wen

2016-10-01

Emotion perception is known to involve multiple operations and waves of analysis, but specific nature of these processes remains poorly understood. Combining psychophysical testing and neurometric analysis of event-related potentials (ERPs) in a fear detection task with parametrically varied fear intensities (N=45), we sought to elucidate key processes in fear perception. Building on psychophysics marking fear perception thresholds, our neurometric model fitting identified several putative operations and stages: four key processes arose in sequence following face presentation - fear-neutral categorization (P1 at 100ms), fear detection (P300 at 320ms), valuation (early subcomponent of the late positive potential/LPP at 400-500ms) and conscious awareness (late subcomponent LPP at 500-600ms). Furthermore, within-subject brain-behavior association suggests that initial emotion categorization was mandatory and detached from behavior whereas valuation and conscious awareness directly impacted behavioral outcome (explaining 17% and 31% of the total variance, respectively). The current study thus reveals the chronometry of fear perception, ascribing psychological meaning to distinct underlying processes. The combination of early categorization and late valuation of fear reconciles conflicting (categorical versus dimensional) emotion accounts, lending support to a hybrid model. Importantly, future research could specifically interrogate these psychological processes in various behaviors and psychopathologies (e.g., anxiety and depression). Copyright © 2016 Elsevier Ltd. All rights reserved.

Incubation behavior adjustments, driven by ambient temperature variation, improve synchrony between hatch dates and caterpillar peak in a wild bird population.

PubMed

Simmonds, Emily G; Sheldon, Ben C; Coulson, Tim; Cole, Ella F

2017-11-01

For organisms living in seasonal environments, synchronizing the peak energetic demands of reproduction with peak food availability is a key challenge. Understanding the extent to which animals can adjust behavior to optimize reproductive timing, and the cues they use to do this, is essential for predicting how they will respond to future climate change. In birds, the timing of peak energetic demand is largely determined by the timing of clutch initiation; however, considerable alterations can still occur once egg laying has begun. Here, we use a wild population of great tits ( Parus major ) to quantify individual variation in different aspects of incubation behavior (onset, duration, and daily intensity) and conduct a comprehensive assessment of the causes and consequences of this variation. Using a 54-year dataset, we demonstrate that timing of hatching relative to peak prey abundance (synchrony) is a better predictor of reproductive success than clutch initiation or clutch completion timing, suggesting adjustments to reproductive timing via incubation are adaptive in this species. Using detailed in-nest temperature recordings, we found that postlaying, birds improved their synchrony with the food peak primarily by varying the onset of incubation, with duration changes playing a lesser role. We then used a sliding time window approach to explore which spring temperature cues best predict variance in each aspect of incubation behavior. Variation in the onset of incubation correlated with mean temperatures just prior to laying; however, incubation duration could not be explained by any of our temperature variables. Daily incubation intensity varied in response to daily maximum temperatures throughout incubation, suggesting female great tits respond to temperature cues even in late stages of incubation. Our results suggest that multiple aspects of the breeding cycle influence the final timing of peak energetic demand. Such adjustments could compensate, in part, for poor initial timing, which has significant fitness impacts.

Developmental trajectories of compensatory exercise and fasting behavior across the middle school years.

PubMed

Davis, Heather A; Guller, Leila; Smith, Gregory T

2016-12-01

Compensatory exercise and fasting behavior, in the absence of binge eating and purging, appear to be important eating disorder behaviors that are associated with dysfunction, but little is known about these behaviors in youth. We studied the trajectories of their development in non-binge eating and non-purging girls during early adolescence. Using a longitudinal design, we assessed 564 girls six times over the three years of middle school (grades 6 through 8) and developed trajectories specifying different developmental patterns in relation to the behaviors. Prior to this period, when the girls were in 5th grade (elementary school), we assessed risk factors to predict girls' subsequent trajectory group membership. Compensatory exercise trajectory groups included a non-engagement group, a group that increased in the behavior, and a group that decreased in the behavior. There were two fasting trajectory groups, one consistently engaging in the behavior and the other consistently not. Elementary school levels of depression, eating expectancies, and thinness expectancies predicted subsequent trajectory group membership. Risk for compensatory exercise and fasting should be evaluated as early as in 5th grade. Targeted interventions should focus on girls in late elementary school or middle school, as this appears to be a critical developmental and maintenance period for compensatory exercise and fasting behavior. Copyright © 2016 Elsevier Ltd. All rights reserved.

Mexican American Adolescents’ Sleep Patterns: Contextual Correlates and Implications for Health and Adjustment in Young Adulthood

PubMed Central

Kuo, Sally I-Chun; Updegraff, Kimberly A.; Zeiders, Katharine H.; McHale, Susan M.; Umaña-Taylor, Adriana J.; De Jesús, Sue A. Rodríguez

2014-01-01

Late adolescence is a period of substantial risk for unhealthy sleep patterns. This study investigated the contextual correlates and health and adjustment implications of sleep patterns among Mexican American youth (N = 246; 51% female). We focused on Mexican American youth because they represent a large and rapidly increasing subgroup of the U.S. population that is at higher risk for health and adjustment problems; this higher risk may be explained, in part, by sleep patterns. Using data from 7 phone diary interviews conducted when youth averaged 18 years of age, we assessed average nighttime sleep duration and night-to-night variability in sleep duration. Guided by socio-ecological models, we first examined how experiences in the family context (time spent and quality of relationships with parents, parents’ familism values) and in extra-familial contexts (school, work, peers) were related to sleep duration and variability. The findings revealed that time spent in school, work, and with peers linked to less sleep. Further, conflict with mothers was related to greater sleep variability. Next, we tested the implications of sleep in late adolescence for health (perceived physical health, body mass index) and adjustment (depressive symptoms, risky behaviors) in young adulthood. These findings indicated that more sleep variability predicted relative decreases in health and increases in risky behaviors, and shorter sleep duration predicted relative decreases in poorer perceived health for males. The discussion highlights the significance of the transition to young adulthood as a target for sleep research and the importance of studying sleep within its socio-cultural context. PMID:25047598

A Unique Assemblage of Engraved Plaquettes from Ein Qashish South, Jezreel Valley, Israel: Figurative and Non-Figurative Symbols of Late Pleistocene Hunters-Gatherers in the Levant.

PubMed

Yaroshevich, Alla; Bar-Yosef, Ofer; Boaretto, Elisabeta; Caracuta, Valentina; Greenbaum, Noam; Porat, Naomi; Roskin, Joel

2016-01-01

Three engraved limestone plaquettes from the recently excavated Epipaleolithic open-air site Ein Qashish South in the Jezreel Valley, Israel comprise unique evidence for symbolic behavior of Late Pleistocene foragers in the Levant. The engravings, uncovered in Kebaran and Geometric Kebaran deposits (ca. 23ka and ca. 16.5ka BP), include the image of a bird-the first figurative representation known so far from a pre-Natufian Epipaleolithic-along with geometric motifs such as chevrons, crosshatchings and ladders. Some of the engravings closely resemble roughly contemporary European finds interpreted as "systems of notations" or "artificial memory systems"-records related to timing of seasonal resources and associated aggregation events of nomadic groups. Moreover, similarly looking signs and patterns are well known from the context of the local Natufian-a final Epipaleolithic culture of sedentary or semi-sedentary foragers who started practicing agriculture. The investigation of the engravings found in Ein Qashish South involves conceptualizations developed in studies of European and local parallels, a selection of ethnographic examples and preliminary microscopic observations of the plaquettes. This shows that the figurative and non-figurative images comprise a coherent assemblage of symbols that might have been applied in order to store, share and transmit information related to social and subsistence realms of mobile bands. It further suggests that the site functioned as a locality of groups' aggregation and indicates social complexity of pre-Natufian foragers in the Levant. While alterations in social and subsistence strategies can explain the varying frequency of image use characterizing different areas of the Late Pleistocene world-the apparent similarity in graphics and the mode of their application support the possibility that symbol-mediated behavior has a common and much earlier origin.

Effect of menstrual cycle phase on corticolimbic brain activation by visual food cues.

PubMed

Frank, Tamar C; Kim, Ginah L; Krzemien, Alicja; Van Vugt, Dean A

2010-12-02

Food intake is decreased during the late follicular phase and increased in the luteal phase of the menstrual cycle. While a changing ovarian steroid milieu is believed to be responsible for this behavior, the specific mechanisms involved are poorly understood. Brain activity in response to visual food stimuli was compared during the estrogen dominant peri-ovulatory phase and the progesterone dominant luteal phase of the menstrual cycle. Twelve women underwent functional magnetic resonance imaging during the peri-ovulatory and luteal phases of the menstrual cycle in a counterbalanced fashion. Whole brain T2* images were collected while subjects viewed pictures of high calorie (HC) foods, low calorie (LC) foods, and control (C) pictures presented in a block design. Blood oxygen level dependent (BOLD) signal in the late follicular phase and luteal phase was determined for the contrasts HC-C, LC-C, HC-LC, and LC-HC. Both HC and LC stimuli activated numerous corticolimbic brain regions in the follicular phase, whereas only HC stimuli were effective in the luteal phase. Activation of the nucleus accumbens (NAc), amygdala, and hippocampus in response to the HC-C contrast and the hippocampus in response to the LC-C contrast was significantly increased in the late follicular phase compared to the luteal phase. Activation of the orbitofrontal cortex and mid cingulum in response to the HC-LC contrast was greater during the luteal phase. These results demonstrate for the first time that brain responses to visual food cues are influenced by menstrual cycle phase. We postulate that ovarian steroid modulation of the corticolimbic brain contributes to changes in ingestive behavior during the menstrual cycle. Copyright © 2010 Elsevier B.V. All rights reserved.

The social transmission of risk: Maternal stress physiology, synchronous parenting, and well-being mediate the effects of war exposure on child psychopathology.

PubMed

Halevi, Galit; Djalovski, Amir; Kanat-Maymon, Yaniv; Yirmiya, Karen; Zagoory-Sharon, Orna; Koren, Lee; Feldman, Ruth

2017-11-01

While chronic early stress increases child susceptibility to psychopathology, risk and resilience trajectories are shaped by maternal social influences whose role requires much further research in longitudinal studies. We examined the social transmission of risk by assessing paths leading from war-exposure to child symptoms as mediated by 3 sources of maternal social influence; stress physiology, synchronous parenting, and psychiatric disorder. Mothers and children living in a zone of continuous war were assessed in early childhood (1.5-5 years) and the current study revisited families in late (9-11years) childhood (N = 177; N = 101 war-exposed; N = 76 controls). At both time-points, maternal and child's salivary cortisol (SC), social behavior, and externalizing and internalizing symptoms were assessed. In late childhood, hair cortisol concentrations (HCC) were also measured and mother and child underwent psychiatric diagnosis. The social transmission model was tested against 2 alternative models; 1 proposing direct impact of war on children without maternal mediation, the other predicting late-childhood symptoms from early childhood variables, not change trajectories. Path analysis controlling for early childhood variables supported our conceptual model. Whereas maternal psychopathology was directly linked with child symptoms, defining direct mediation, the impact of maternal stress hormones was indirect and passed through stress contagion mechanisms involving coupling between maternal and child's HCC and SC. Similarly, maternal synchrony linked with child social engagement as the pathway to reduced symptomatology. Findings underscore the critical role of maternal stress physiology, attuned behavior, and well-being in shaping child psychopathology amid adversity and specify direct and indirect paths by which mothers stand between war and the child. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Aging and emotional memory: the co-occurrence of neurophysiological and behavioral positivity effects.

PubMed

Langeslag, Sandra J E; van Strien, Jan W

2009-06-01

The positivity effect is a trend for adults to increasingly process positive and/or decreasingly process negative information compared with other information with advancing age. The positivity effect has been observed with behavioral measures, such as in attention and memory tests, and with measures of neurophysiological activity, such as in amygdala activation and the late positive potential (LPP). In this study, it was investigated whether these behavioral and neurophysiological positivity effects co-occur. The electroencephalogram of younger (19-26 years) and older (65-82 years) adults was recorded while they encoded unpleasant, neutral, and pleasant pictures for retrieval in free and cued recall tests. Positivity effects occurred in the late LPP amplitude (700-1,000 ms) and in the free recall test, with negativity biases in younger adults and no biases in older adults. The occurrence of a valence bias in the LPP was substantially but nonsignificantly correlated with the occurrence of a similar valence bias in memory in the older adults. In conclusion, neurophysiological and behavioral positivity effects appear to co-occur, a finding that awaits expansion using different neurophysiological and behavioral measures.

Influence of gonadotropin-releasing hormone and timing of insemination relative to estrus on pregnancy rates of dairy cattle at first service.

PubMed

Mee, M O; Stevenson, J S; Scoby, R K; Folman, Y

1990-06-01

The objective was to determine the influence of gonadotropin-releasing hormone on pregnancy rates of dairy cattle at first services, when both the timing of hormone injection and insemination were altered relative to the onset of estrus. Cows (n = 325) were assigned randomly to six groups making up a 2 X 2 X 2 incomplete factorial experiment; dose of GnRH (100 micrograms versus saline), timing [1 h (early) or 12 to 16 h (late) after first detected estrus] of AI, and timing of hormone injection (early versus late) were the three main effects. Cows were observed for estrus 4 times daily. Treatments and resulting pregnancy rates were: 1) hormone injection early plus AI early (35%), 2) hormone injection late plus AI early (34%), 3) saline injection early plus AI early (30%), 4) hormone injection late plus AI late (30%), 5) hormone injection early plus AI late (46%), and 6) saline injection late plus AI late (43%). Pregnancy rate in the first four groups (32%) was less than that in the latter two groups (44%). Concentrations of LH in serum were greater for cows given hormone or saline injections in early estrus than for cows injected with either hormone of saline during late estrus. Concentrations of LH in serum 2 h after GnRH were elevated above those of controls, whether GnRH was injected during early or late estrus. Neither concentrations of LH during estrus nor concentrations of progesterone 8 to 14 d after estrus explained the possible antifertility effect of GnRH given during late estrus.(ABSTRACT TRUNCATED AT 250 WORDS)

Neuroinflammation, myelin and behavior: Temporal patterns following mild traumatic brain injury in mice

PubMed Central

Taib, Toufik; Leconte, Claire; Van Steenwinckel, Juliette; Cho, Angelo H.; Palmier, Bruno; Torsello, Egle; Lai Kuen, Rene; Onyeomah, Somfieme; Ecomard, Karine; Benedetto, Chiara; Coqueran, Bérard; Novak, Anne-Catherine; Deou, Edwige; Plotkine, Michel; Gressens, Pierre; Marchand-Leroux, Catherine

2017-01-01

Traumatic brain injury (TBI) results in white matter injury (WMI) that is associated with neurological deficits. Neuroinflammation originating from microglial activation may participate in WMI and associated disorders. To date, there is little information on the time courses of these events after mild TBI. Therefore we investigated (i) neuroinflammation, (ii) WMI and (iii) behavioral disorders between 6 hours and 3 months after mild TBI. For that purpose, we used experimental mild TBI in mice induced by a controlled cortical impact. (i) For neuroinflammation, IL-1b protein as well as microglial phenotypes, by gene expression for 12 microglial activation markers on isolated CD11b+ cells from brains, were studied after TBI. IL-1b protein was increased at 6 hours and 1 day. TBI induced a mixed population of microglial phenotypes with both pro-inflammatory, anti-inflammatory and immunomodulatory markers from 6 hours to 3 days post-injury. At 7 days, microglial activation was completely resolved. (ii) Three myelin proteins were assessed after TBI on ipsi- and contralateral corpus callosum, as this structure is enriched in white matter. TBI led to an increase in 2',3'-cyclic-nucleotide 3'-phosphodiesterase, a marker of immature and mature oligodendrocyte, at 2 days post-injury; a bilateral demyelination, evaluated by myelin basic protein, from 7 days to 3 months post-injury; and an increase in myelin oligodendrocyte glycoprotein at 6 hours and 3 days post-injury. Transmission electron microscopy study revealed various myelin sheath abnormalities within the corpus callosum at 3 months post-TBI. (iii) TBI led to sensorimotor deficits at 3 days post-TBI, and late cognitive flexibility disorder evidenced by the reversal learning task of the Barnes maze 3 months after injury. These data give an overall invaluable overview of time course of neuroinflammation that could be involved in demyelination and late cognitive disorder over a time-scale of 3 months in a model of mild TBI. This model could help to validate a pharmacological strategy to prevent post-traumatic WMI and behavioral disorders following mild TBI. PMID:28910378

Cognitive-Behavior Therapy for Late-Life Insomnia.

ERIC Educational Resources Information Center

Morin, Charles M.; And Others

1993-01-01

Assigned 24 older adults with persistent psychophysiological insomnia to immediate or delayed cognitive-behavioral intervention in waiting-list control group design. Treatment was effective in reducing sleep latency, wake after sleep onset, and early morning awakening, and in increasing sleep efficiency. Sleep improvements obtained by…

A late wake time phase delays the human dim light melatonin rhythm.

PubMed

Burgess, Helen J; Eastman, Charmane I

2006-03-13

Short sleep/dark durations, due to late bedtimes or early wake times or both, are common in modern society. We have previously shown that a series of days with a late bedtime phase delays the human dim light melatonin rhythm, as compared to a series of days with an early bedtime, despite a fixed wake time. Here we compared the effect of an early versus late wake time with a fixed bedtime on the human dim light melatonin rhythm. Fourteen healthy subjects experienced 2 weeks of short 6h nights with an early wake time fixed at their habitual weekday wake time and 2 weeks of long 9 h nights with a wake time that occurred 3h later than the early wake time, in counterbalanced order. We found that after 2 weeks with the late wake time, the dim light melatonin onset delayed by 2.4 h and the dim light melatonin offset delayed by 2.6 h (both p < 0.001), as compared to after 2 weeks with the early wake time. These results highlight the substantial influence that wake time, likely via the associated morning light exposure, has on the timing of the human circadian clock. Furthermore, the results suggest that when people truncate their sleep by waking early their circadian clocks phase advance and when people wake late their circadian clocks phase delay.

Risky Decision Making in a Laboratory Driving Task Is Associated with Health Risk Behaviors during Late Adolescence but Not Adulthood

ERIC Educational Resources Information Center

Kim-Spoon, Jungmeen; Kahn, Rachel; Deater-Deckard, Kirby; Chiu, Pearl; Steinberg, Laurence; King-Casas, Brooks

2016-01-01

Adolescence is characterized by increasing incidence of health risk behaviors, including experimentation with drugs and alcohol. To fill the gap in our understanding of the associations between risky decision-making and health risk behaviors, we investigated associations between laboratory-based risky decision-making using the Stoplight task and…

Young Women's Perceptions of and Attitudes towards Mental Health and Mental Illness: A Qualitative Interview Study

ERIC Educational Resources Information Center

McQuoid, Courtney

2010-01-01

Late adolescents face a multitude of stressors in their daily lives and must find ways to weather this distress. The attitudes and beliefs late adolescents hold about seeking formal help when appropriate can influence their engagement in formal help seeking behaviors. Previous research suggests that adolescents' willingness to seek help for mental…

Changes in Daily Newspapers: Implications for Community Political Behavior.

ERIC Educational Resources Information Center

Smith, Michael V.

A decline in the daily reading of newspapers has been observed in the United States since World War II. In the decade from the late 1960s to the late 1970s, most daily newspapers employed market research to document and diagnose trends in readership, to estimate their present and future audiences' composition, and to assess the audiences'…

Mediational and Deviance Theories of Late High School Failure: Process Roles of Structural Strains, Academic Competence, and General versus Specific Problem Behavior

ERIC Educational Resources Information Center

Newcomb, Michael D.; Abbott, Robert D.; Catalano, Richard F.; Hawkins, J. David; Battin-Pearson, Sara; Hill, Karl

2002-01-01

Understanding and preventing high school failure is a national priority. Structural strain and general deviance theories attempt to explain late high school failure. The authors tested the hypotheses that general (vs. specific) deviance and academic competence mediate the relationships between structural strain factors (gender, ethnicity, and…

Childhood Predictors of Male Criminality: A Prospective Population-Based Follow-up Study from Age 8 to Late Adolescence

ERIC Educational Resources Information Center

Sourander, Andre; Elonheimo, Henrik; Niemela, Solja; Nuutila, Ari-Matti; Helenius, Hans; Sillanmaki, Lauri; Piha, Jorma; Tamminen, Tuula; Kumpulainen, Kirsti; Moilanen, Irma; Almqvist, Frederik

2006-01-01

Objective: To study childhood predictors for late adolescence criminality. Method: The follow-up sample included 2,713 Finnish boys born in 1981. Information about the 8-year-old boys' problem behavior was obtained from parents, teachers, and the children themselves. The follow-up information about criminal offenses was based on the national…

Addressing the human and technical dimensions of potato IPM using farmer field schools (FFS): CIP and partners' experience on late blight management

USDA-ARS?s Scientific Manuscript database

Starting in the 1990’s, the International Potato Center (CIP)’s integrated pest management team for potato late blight (IPM-LB) realized the importance of addressing the management of this complex potato disease by combining crop protection and management sciences, with social and behavioral science...

Oppositional Defiant Disorder dimensions: genetic influences and risk for later psychopathology

PubMed Central

Mikolajewski, Amy J.; Taylor, Jeanette; Iacono, William G.

2016-01-01

Background This study was undertaken to determine how well two Oppositional Defiant Disorder (ODD) dimensions (irritable and headstrong/hurtful) assessed in childhood predict late adolescent psychopathology and the degree to which these outcomes can be attributed to genetic influences shared with ODD dimensions. Methods Psychopathology was assessed via diagnostic interviews of 1225 twin pairs at ages 11 and 17. Results Consistent with hypotheses, the irritable dimension uniquely predicted overall internalizing problems, whereas the headstrong/hurtful dimension uniquely predicted substance use disorder symptoms. Both dimensions were predictive of antisocial behavior, and overall externalizing problems. The expected relationships between the irritable dimension and specific internalizing disorders were not found. Twin modeling showed the irritable and headstrong/hurtful dimensions were related to late adolescent psychopathology symptoms through common genetic influences. Conclusions Symptoms of ODD in childhood pose a significant risk for various mental health outcomes in late adolescence. Further, common genetic influences underlie the covariance between irritable symptoms in childhood and overall internalizing problems in late adolescence, whereas headstrong/hurtful symptoms share genetic influences with substance use disorder symptoms. Antisocial behavior and overall externalizing share common genetic influences with both the irritable and headstrong/hurtful dimensions. PMID:28059443

How Does Psychosocial Behavior Contribute to Cognitive Health in Old Age?

PubMed Central

Wilson, Robert S.; Bennett, David A.

2017-01-01

With the aging of the U.S. population, the number of cognitively disabled persons is expected to substantially increase in coming decades, underscoring the urgent need for effective interventions. Here, we review the current evidence linking psychosocial factors to late-life cognitive loss and consider the study design needed to illuminate the biologic bases of the associations. We then examine an ongoing study that includes several of the key design elements, the Rush Memory and Aging Project. In this longitudinal clinical-pathological cohort study, indicators of personality, social connectedness, and psychological well-being were shown to predict late-life cognitive outcomes. Participants who died underwent a uniform neuropathologic examination to quantify common dementia-related pathologies. Some psychosocial indicators were associated with cerebral infarction; some indicators modified the association of neurodegenerative pathologies with cognitive loss; and the association of some indicators with cognitive outcomes appears to be independent of the pathologies traditionally associated with late-life dementia. These findings suggest that psychosocial behavior influences late-life cognitive health through multiple neurobiologic mechanisms. A better understanding of these mechanisms may lead to novel strategies for preserving cognitive health in old age. PMID:28545247

Oppositional defiant disorder dimensions: genetic influences and risk for later psychopathology.

PubMed

Mikolajewski, Amy J; Taylor, Jeanette; Iacono, William G

2017-06-01

This study was undertaken to determine how well two oppositional defiant disorder (ODD) dimensions (irritable and headstrong/hurtful) assessed in childhood predict late adolescent psychopathology and the degree to which these outcomes can be attributed to genetic influences shared with ODD dimensions. Psychopathology was assessed via diagnostic interviews of 1,225 twin pairs at ages 11 and 17. Consistent with hypotheses, the irritable dimension uniquely predicted overall internalizing problems, whereas the headstrong/hurtful dimension uniquely predicted substance use disorder symptoms. Both dimensions were predictive of antisocial behavior and overall externalizing problems. The expected relationships between the irritable dimension and specific internalizing disorders were not found. Twin modeling showed that the irritable and headstrong/hurtful dimensions were related to late adolescent psychopathology symptoms through common genetic influences. Symptoms of ODD in childhood pose a significant risk for various mental health outcomes in late adolescence. Further, common genetic influences underlie the covariance between irritable symptoms in childhood and overall internalizing problems in late adolescence, whereas headstrong/hurtful symptoms share genetic influences with substance use disorder symptoms. Antisocial behavior and overall externalizing share common genetic influences with both the irritable and headstrong/hurtful dimensions. © 2017 Association for Child and Adolescent Mental Health.

FISH-detected delay in replication timing of mutated FMR1 alleles on both active and inactive X-chromosomes.

PubMed

Yeshaya, J; Shalgi, R; Shohat, M; Avivi, L

1999-01-01

X-chromosome inactivation and the size of the CGG repeat number are assumed to play a role in the clinical, physical, and behavioral phenotype of female carriers of a mutated FMR1 allele. In view of the tight relationship between replication timing and the expression of a given DNA sequence, we have examined the replication timing of FMR1 alleles on active and inactive X-chromosomes in cell samples (lymphocytes or amniocytes) of 25 females: 17 heterozygous for a mutated FMR1 allele with a trinucleotide repeat number varying from 58 to a few hundred, and eight homozygous for a wild-type allele. We have applied two-color fluorescence in situ hybridization (FISH) with FMR1 and X-chromosome alpha-satellite probes to interphase cells of the various genotypes: the alpha-satellite probe was used to distinguish between early replicating (active) and late replicating (inactive) X-chromosomes, and the FMR1 probe revealed the replication pattern of this locus. All samples, except one with a large trinucleotide expansion, showed an early replicating FMR1 allele on the active X-chromosome and a late replicating allele on the inactive X-chromosome. In samples of mutation carriers, both the early and the late alleles showed delayed replication compared with normal alleles, regardless of repeat size. We conclude therefore that: (1) the FMR1 locus is subjected to X-inactivation; (2) mutated FMR1 alleles, regardless of repeat size, replicate later than wild-type alleles on both the active and inactive X-chromosomes; and (3) the delaying effect of the trinucleotide expansion, even with a low repeat size, is superimposed on the delay in replication associated with X-inactivation.

Calibration of the Late Cretaceous to Paleocene geomagnetic polarity and astrochronological time scales: new results from high-precision U-Pb geochronology

NASA Astrophysics Data System (ADS)

Ramezani, Jahandar; Clyde, William; Wang, Tiantian; Johnson, Kirk; Bowring, Samuel

2016-04-01

Reversals in the Earth's magnetic polarity are geologically abrupt events of global magnitude that makes them ideal timelines for stratigraphic correlation across a variety of depositional environments, especially where diagnostic marine fossils are absent. Accurate and precise calibration of the Geomagnetic Polarity Timescale (GPTS) is thus essential to the reconstruction of Earth history and to resolving the mode and tempo of biotic and environmental change in deep time. The Late Cretaceous - Paleocene GPTS is of particular interest as it encompasses a critical period of Earth history marked by the Cretaceous greenhouse climate, the peak of dinosaur diversity, the end-Cretaceous mass extinction and its paleoecological aftermaths. Absolute calibration of the GPTS has been traditionally based on sea-floor spreading magnetic anomaly profiles combined with local magnetostratigraphic sequences for which a numerical age model could be established by interpolation between an often limited number of 40Ar/39Ar dates from intercalated volcanic ash deposits. Although the Neogene part of the GPTS has been adequately calibrated using cyclostratigraphy-based, astrochronological schemes, the application of these approaches to pre-Neogene parts of the timescale has been complicated given the uncertainties of the orbital models and the chaotic behavior of the solar system this far back in time. Here we present refined chronostratigraphic frameworks based on high-precision U-Pb geochronology of ash beds from the Western Interior Basin of North America and the Songliao Basin of Northeast China that places tight temporal constraints on the Late Cretaceous to Paleocene GPTS, either directly or by testing their astrochronological underpinnings. Further application of high-precision radioisotope geochronology and calibrated astrochronology promises a complete and robust Cretaceous-Paleogene GPTS, entirely independent of sea-floor magnetic anomaly profiles.

Impacts of frequent, acute pulses of corticosterone on condition and behavior of Gambel's white-crowned sparrow (Zonotrichia leucophrys gambelii).

PubMed

Busch, D Shallin; Sperry, Todd S; Peterson, Eric; Do, Cam-Tu; Wingfield, John C; Boyd, Ellen H

2008-09-15

Little is known about how frequent, acute stressors affect wild animals. We present two experiments conducted on captive, Gambel's white-crowned sparrow (Zonotrichia leucophrys gambelii) that explore how frequent, acute doses of corticosterone (CORT) affect condition and behavior. CORT was administered either once or three times a day to birds in pre-breeding, early-breeding, or late-breeding life-history stages. Two additional groups were included to control for the CORT delivery vehicle, DMSO, and the treatment process. Our results indicate that CORT treatment decreases condition, but that its effects are dependent on frequency and life stage. Specifically, CORT-treated birds delayed the onset of molt and had reduced body mass, flight muscle, and food consumption. CORT treatment did not affect fat stores, bile retention in the gallbladder, or the expression of migratory restlessness behavior. These results increase our understanding of the effects of frequent, acute stressors and the development of chronic stress states.

The Ontogeny of Exploratory Behavior in Male and Female Adolescent Rats (Rattus norvegicus)

PubMed Central

Lynn, Debra A; Brown, Gillian R

2009-01-01

During adolescence, rats gain independence from their mothers and disperse from the natal burrow, with males typically dispersing further than females. We predicted that, if dispersal patterns are associated with responsiveness to novelty, exploratory behavior in novel environments would increase across adolescence, and males would explore more than females. Alternatively, females might explore more than males, if females are more motivated than males to learn about the immediate environment or if females have poorer spatial abilities than males. Twenty-five male and 21 female rats were exposed to two novel environments (open field and elevated plus-maze) during early, mid-, or late adolescence. Total locomotion and amount of exploration directed towards aversive areas increased across adolescence, even when body weight was included as a covariate. Female adolescents locomoted more and spent more time exploring aversive areas than males. Developmental changes in neural function potentially underlie age and sex differences in exploratory behavior. © 2009 Wiley Periodicals, Inc. Dev Psychobiol 51: 513–520, 2009. PMID:19582791

The ontogeny of exploratory behavior in male and female adolescent rats (Rattus norvegicus).

PubMed

Lynn, Debra A; Brown, Gillian R

2009-09-01

During adolescence, rats gain independence from their mothers and disperse from the natal burrow, with males typically dispersing further than females. We predicted that, if dispersal patterns are associated with responsiveness to novelty, exploratory behavior in novel environments would increase across adolescence, and males would explore more than females. Alternatively, females might explore more than males, if females are more motivated than males to learn about the immediate environment or if females have poorer spatial abilities than males. Twenty-five male and 21 female rats were exposed to two novel environments (open field and elevated plus-maze) during early, mid-, or late adolescence. Total locomotion and amount of exploration directed towards aversive areas increased across adolescence, even when body weight was included as a covariate. Female adolescents locomoted more and spent more time exploring aversive areas than males. Developmental changes in neural function potentially underlie age and sex differences in exploratory behavior. (c) 2009 Wiley Periodicals, Inc. Dev Psychobiol 51: 513-520, 2009.

Influence of aggression on information processing in the emotional stroop task--an event-related potential study.

PubMed

Bertsch, Katja; Böhnke, Robina; Kruk, Menno R; Naumann, Ewald

2009-01-01

Aggression is a common behavior which has frequently been explained as involving changes in higher level information processing patterns. Although researchers have started only recently to investigate information processing in healthy individuals while engaged in aggressive behavior, the impact of aggression on information processing beyond an aggressive encounter remains unclear. In an event-related potential study, we investigated the processing of facial expressions (happy, angry, fearful, and neutral) in an emotional Stroop task after experimentally provoking aggressive behavior in healthy participants. Compared to a non-provoked group, these individuals showed increased early (P2) and late (P3) positive amplitudes for all facial expressions. For the P2 amplitude, the effect of provocation was greatest for threat-related expressions. Beyond this, a bias for emotional expressions, i.e., slower reaction times to all emotional expressions, was found in provoked participants with a high level of trait anger. These results indicate significant effects of aggression on information processing, which last beyond the aggressive encounter even in healthy participants.

Anxiety and spatial attention moderate the electrocortical response to aversive pictures.

PubMed

MacNamara, Annmarie; Hajcak, Greg

2009-11-01

Aversive stimuli capture attention and elicit increased neural activity, as indexed by behavioral, electrocortical and hemodynamic measures; moreover, individual differences in anxiety relate to a further increased sensitivity to threatening stimuli. Evidence has been mixed, however, as to whether aversive pictures elicit increased neural response when presented in unattended spatial locations. In the current study, ERP and behavioral data were recorded from 49 participants as aversive and neutral pictures were simultaneously presented in spatially attended and unattended locations; on each trial, participants made same/different judgments about pictures presented in attended locations. Aversive images presented in unattended locations resulted in increased error rate and reaction time. The late positive potential (LPP) component of the ERP was only larger when aversive images were presented in attended locations, and this increase was positively correlated with self-reported state anxiety. Findings are discussed in regard to the sensitivity of ERP and behavioral responses to aversive distracters, and in terms of increased neural processing of threatening stimuli in anxiety.

The impact of delinquency on young adult sexual risk behaviors and sexually transmitted infections.

PubMed

Aalsma, Matthew C; Tong, Yan; Wiehe, Sarah E; Tu, Wanzhu

2010-01-01

Youth in the juvenile justice system have increased sexual risk behavior and sexually transmitted infections (STI). However, research exploring the effect of self-reported delinquency on sexual risk behavior and STI is limited, and results vary depending on the populations studied. Therefore, we used nationally representative data to examine the longitudinal association between delinquent behavior, sexual risk behavior, and STI among adolescents and young adults. We used a sample of 10,828 participants from the National Longitudinal Study of Adolescent and Health. Outcomes included STI and sexual risk behavior from Wave III (17-27-year-olds). Predictors for the generalized linear regression models (stratified by gender) include race, age, education, relationship status at Wave III, and delinquent behavior groups (life-course persistent, adolescence-limited, late-onset and nondelinquency). None of the delinquency groups were associated with young adult STI. Only life-course persistent delinquency was associated consistently with sexual risk behavior (except for condom use). The adolescence-limited and late-onset groups had limited effects on sexual risk outcomes. Life-course persistent delinquency influences the expression of young adult sexual risk behavior. However, delinquent behavior does not predict STI in a population-based sample of youth. Programs and interventions that address the sexual health of youth need to consider the role of delinquency in shaping sexual risk behaviors, and future research should explore broader societal and environmental risk factors on STIs. Copyright 2010 Society for Adolescent Medicine. Published by Elsevier Inc. All rights reserved.

Pollinator-mediated interactions in experimental arrays vary with neighbor identity.

PubMed

Ha, Melissa K; Ivey, Christopher T

2017-02-01

Local ecological conditions influence the impact of species interactions on evolution and community structure. We investigated whether pollinator-mediated interactions between coflowering plants vary with plant density, coflowering neighbor identity, and flowering season. We conducted a field experiment in which flowering time and floral neighborhood were manipulated in a factorial design. Early- and late-flowering Clarkia unguiculata plants were placed into arrays with C. biloba neighbors, noncongeneric neighbors, additional conspecific plants, or no additional plants as a density control. We compared whole-plant pollen limitation of seed set, pollinator behavior, and pollen deposition among treatments. Interactions mediated by shared pollinators depended on the identity of the neighbor and possibly changed through time, although flowering-season comparisons were compromised by low early-season plant survival. Interactions with conspecific neighbors were likely competitive late in the season. Interactions with C. biloba appeared to involve facilitation or neutral interactions. Interactions with noncongeners were more consistently competitive. The community composition of pollinators varied among treatment combinations. Pollinator-mediated interactions involved competition and likely facilitation, depending on coflowering neighbor. Experimental manipulation helped to reveal context-dependent variation in indirect biotic interactions. © 2017 Botanical Society of America.

Suicides in Late Life

PubMed Central

Van Orden, Kimberly; Conwell, Yeates

2011-01-01

Suicide in late life is an enormous public health problem that will likely increase in severity as adults of the baby boom generation age. Data from psychological autopsy studies supplemented with recent studies of suicidal ideation and attempts point to a consistent set of risk factors for the spectrum of suicidal behaviors in late life (suicide ideation, attempts, and deaths). Clinicians should be vigilant for psychiatric illness (especially depression), physical illness, pain, functional impairment, and social disconnectedness. Recent advances in late-life suicide prevention have in common collaborative, multifaceted intervention designs. We suggest that one mechanism shared by all preventive interventions shown to reduce the incidence of late-life suicide is the promotion of connectedness. For the clinician working with older adults, our recommendation is to not only consider risk factors, such as depression, and implement appropriate treatments but to enhance social connectedness as well. PMID:21369952

Associations between lying behavior and lameness in Canadian Holstein-Friesian cows housed in freestall barns.

PubMed

Solano, L; Barkema, H W; Pajor, E A; Mason, S; LeBlanc, S J; Nash, C G R; Haley, D B; Pellerin, D; Rushen, J; de Passillé, A M; Vasseur, E; Orsel, K

2016-03-01

Lying behavior is an important measure of comfort and well-being in dairy cattle, and changes in lying behavior are potential indicators and predictors of lameness. Our objectives were to determine individual and herd-level risk factors associated with measures of lying behavior, and to evaluate whether automated measures of lying behavior can be used to detect lameness. A purposive sample of 40 Holstein cows was selected from each of 141 dairy farms in Alberta, Ontario, and Québec. Lying behavior of 5,135 cows between 10 and 120 d in milk was automatically and continuously recorded using accelerometers over 4 d. Data on factors hypothesized to influence lying behavior were collected, including information on individual cows, management practices, and facility design. Associations between predictor variables and measures of lying behavior were assessed using generalized linear mixed models, including farm and province as random and fixed effects, respectively. Logistic regression models were used to determine whether lying behavior was associated with lameness. At the cow-level, daily lying time increased with increasing days in milk, but this effect interacted with parity; primiparous cows had more frequent but shorter lying bouts in early lactation, changing to mature-cow patterns of lying behavior (fewer and longer lying bouts) in late lactation. In barns with stall curbs >22 cm high, the use of sand or >2 cm of bedding was associated with an increased average daily lying time of 1.44 and 0.06 h/d, respectively. Feed alleys ≥ 350 cm wide or stalls ≥ 114 cm wide were associated with increased daily lying time of 0.39 and 0.33 h/d, respectively, whereas rubber flooring in the feed alley was associated with 0.47 h/d lower average lying time. Lame cows had longer lying times, with fewer, longer, and more variable duration of bouts compared with nonlame cows. In that regard, cows with lying time ≥ 14 h/d, ≤ 5 lying bouts per day, bout duration ≥ 110 min/bout, or standard deviations of bout duration over 4 d ≥ 70 min had 3.7, 1.7, 2.5, and 3.0 higher odds of being lame, respectively. Factors related to comfort of lying and standing surfaces significantly affected lying behavior. Finally, we inferred that automated measures of lying behavior could contribute to lameness detection, especially when interpreted in the context of other factors known to affect lying behavior, including those associated with the individual cow (e.g., parity and stage of lactation) or environment (e.g., stall surface). Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

The role of interpretation processes and parental discussion in the media's effects on adolescents' use of alcohol.

PubMed

Austin, E W; Pinkleton, B E; Fujioka, Y

2000-02-01

The process that connects media use with alcohol-related beliefs and behaviors has not been well documented. To address this issue, we examined adolescents' viewing patterns, beliefs about alcohol and media messages, and parental discussion of media messages in the context of a theoretical model of message interpretation processes. Measures included the degree to which adolescents found portrayals desirable, realistic, and similar to their own lives; the degree to which they wanted to be like (identify with) the portrayals; and the degree to which they associated positive outcomes with drinking alcohol (expectancies). Cross-sectional survey. Two public high schools in the California central coastal area that include a diverse population in terms of ethnic origin, income level, and education level. Ninth-grade students (n = 252) and 12th-grade students (n = 326). Students reported the number of days within the past week watching various genres of television content, along with perceptions of realism of content, desirability of portrayals, identification with portrayals, expectancies toward alcohol use, personal norms for alcohol use, desire for products with alcohol logos, current alcohol use, frequency of parental reinforcement, and counter-reinforcement of television messages. Associations were examined via hierarchical multiple regression analysis. Effects of media exposure on drinking behavior, controlling for grade level, ethnicity, gender, household income, and education levels were primarily positive and indirect, operating through a number of intervening beliefs, especially expectancies (beta =.59; r(2) =.33). Direct associations, primarily with exposure to late-night talk shows (beta =.12; r(2) =.01), were small. Parental discussion also affected behavior indirectly, operating through expectancies, identification, and perceived realism. The appeal of products with alcohol logos, which was higher among the younger students (t = 3.44) and predicted by expectancies (beta =. 37; r(2) =.13), sports viewing (beta =.17; r(2) =.03) and late-night talk shows (beta =.10; r(2) =.01), predicted actual drinking behavior (beta =.22; r(2) =.04). Drinking behavior was higher among the older students (t = -2.515). Adolescents make drinking decisions using a progressive, logical decision-making process that can be overwhelmed by wishful thinking. The potential risk of frequent exposure to persuasive alcohol portrayals via late-night talk shows, sports, music videos, and prime-time television for underage drinking is moderated by parental reinforcement and counter-reinforcement of messages. Interventions need to acknowledge and counter the appeal of desirable and seemingly realistic alcohol portrayals in the media and alert parents to their potential for unintended adverse effects.

Negative eating attitudes and behaviors among adolescents: The role of parental control and perceived peer support.

PubMed

Pace, Ugo; D'Urso, Giulio; Zappulla, Carla

2018-02-01

In the present study, we examined from a longitudinal perspective the relationship between parental (both maternal and paternal) psychological control, perceived peer support, and negative eating attitudes and behaviors, focusing on the moderating role that perceived peer support may play in the relationship between parental psychological control in early adolescence and negative eating attitudes and behaviors in late adolescence. In Wave 1, participants were 507 adolescents (249 boys and 258 girls) aged from 14 to 15 years (M = 14.76; SD = 0.63). Three years later (Wave 2), the same adolescents participated again in the study (M = 17.88 years; SD = 0.57). Regression analyses displayed that paternal, but not maternal, achievement-oriented psychological control during early adolescence positively predicted negative eating attitudes and behaviors in late adolescence, whereas perceived peer support negatively predicted negative eating attitudes and behaviors. Results also showed a moderator effect of perceived peer support in the relationship between father's psychological control and negative eating attitudes and behaviors, such that at higher levels of paternal achievement-oriented psychological control, negative eating attitudes and behaviors tended to be higher when perceived peer support was low and to be lower when perceived peer support was high. Copyright © 2017. Published by Elsevier Ltd.

Physical Activity Motivation in Late Adolescence: Refinement of a Recent Multidimensional Model

ERIC Educational Resources Information Center

Martin, Andrew J.

2010-01-01

Recent research (Martin et al., 2006) presented a new, multidimensional approach to physical activity motivation (using the Physical Activity Motivation Scale [PAMS]) operationalized through four factors: adaptive cognition, adaptive behavior, impeding/maladaptive cognition, and maladaptive behavior. The present study extends this early research…

Moral Cognition: Explaining the Gender Difference in Antisocial Behavior.

ERIC Educational Resources Information Center

Barriga, Alvaro Q.; Morrison, Elizabeth M.; Liau, Albert K.; Gibbs, John C.

2001-01-01

Examined whether gender discrepancy in late adolescents' antisocial behavior may be attributed to gender differences in other moral cognitive variables. Found that mature moral judgment and higher moral self-relevance were associated with lower self-serving cognitive distortion, partially mediating the relationship between those variables and…

Acute exposure to ethanol on gestational day 15 affects social motivation of female offspring.

PubMed

Varlinskaya, Elena I; Mooney, Sandra M

2014-03-15

Alterations in social behavior are a hallmark of many neurodevelopmental disorders in humans. In rodents, social behavior is affected by prenatal insults. The outcomes are dependent on the timing of the insult as well as the sex and age of the animal tested. The limbic system is particularly important for social behavior, and a peak of neurogenesis within this system occurs on gestational day (G)15. Neurons appear particularly vulnerable to ethanol insult around the time they become post-mitotic. We tested the hypothesis that acute exposure to ethanol on G15 would result in significant social behavior deficits. Accordingly, Long Evans pregnant females were injected with ethanol (2.9 g/kg) or an equivalent volume of saline on G15. Offspring were assessed in a modified social interaction test on postnatal day (P) 28, P42, or P75, i.e., during early adolescence, late adolescence, or young adulthood. Prenatal ethanol exposure decreased social investigation in P28 females and transformed social preference into social avoidance in 75-day-old females. Contact behavior, play fighting, and locomotor activity differed as a function of age, but were not significantly affected by ethanol exposure. Males demonstrated significantly more contact behavior and play fighting at P42 than at P28 or P70, whereas there were no age-related changes in females. Adult females showed more locomotor activity than adult males. Overall, prenatal ethanol exposure on G15 enhanced social anxiety in females, with these effects seen in adulthood only. Copyright © 2013 Elsevier B.V. All rights reserved.

[The history of the pituitary gland: evolution of mental representation and concepts over time].

PubMed

Jedidi, H; Jedidi, Z; Beckers, A

2014-02-01

The hypothalamo pituitary axis, as the true conductor of the endocrine orchestra, is frequently involved in a large variety of pathological conditions such as acromegaly, behavioral disorders, obesity or dwarfism. It is paradoxical to note that, in spite of its importance, this system has been almost ignored by the physiologists of the late centuries. From the physiological conceptions of the physicians and philosophers of antiquity to the theories of the medieval and of the Renaissance physiologists, we will try to understand why the role of pituitary remained so long unrecognized.

The effect of learning on feedback-related potentials in adolescents with dyslexia: an EEG-ERP study.

PubMed

Kraus, Dror; Horowitz-Kraus, Tzipi

2014-01-01

Individuals with dyslexia exhibit associated learning deficits and impaired executive functions. The Wisconsin Card Sorting Test (WCST) is a learning-based task that relies heavily on executive functioning, in particular, attention shift and working memory. Performance during early and late phases of a series within the task represents learning and implementation of a newly learned rule. Here, we aimed to examine two event-related potentials associated with learning, feedback-related negativity (FRN)-P300 complex, in individuals with dyslexia performing the WCST. Adolescents with dyslexia and age-matched typical readers performed the Madrid card sorting test (MCST), a computerized version of the WCST. Task performance, reading measures, and cognitive measures were collected. FRN and the P300 complex were acquired using the event-related potentials methodology and were compared in early vs late errors within a series. While performing the MCST, both groups showed a significant reduction in average reaction times and a trend toward decreased error rates. Typical readers performed consistently better than individuals with dyslexia. FRN amplitudes in early phases were significantly smaller in dyslexic readers, but were essentially equivalent to typical readers in the late phase. P300 amplitudes were initially smaller among readers with dyslexia and tended to decrease further in late phases. Differences in FRN amplitudes for early vs late phases were positively correlated with those of P300 amplitudes in the entire sample. Individuals with dyslexia demonstrate a behavioral and electrophysiological change within single series of the MCST. However, learning patterns seem to differ between individuals with dyslexia and typical readers. We attribute these differences to the lower baseline performance of individuals with dyslexia. We suggest that these changes represent a fast compensatory mechanism, demonstrating the importance of learning strategies on reading among individuals with dyslexia.

Response inhibition difficulties in preterm children aged 9-12 years: Relations with emotion and behavior.

PubMed

Réveillon, Morgane; Borradori Tolsa, Cristina; Monnier, Maryline; Hüppi, Petra S; Barisnikov, Koviljka

2016-01-01

Previous studies with children have demonstrated inhibition difficulties associated with prematurity, but the question of potentially catching up with a delay in inhibition processes before adolescence still remains. Moreover, preterm adolescents are more at risk than their term-born peers for presenting behavioral problems such as emotional difficulties and attention deficit/hyperactivity disorder. In addition to examining response inhibition, this study addressed, for the first time, the impact of an emotional context on response inhibition abilities and its relation to behavioral problems in late school-aged preterm children. Fifty-eight preterm children aged 9-12 years were compared with 61 controls on two versions of a stop-signal task, the Delay Frustration Task, and the Strengths and Difficulties Questionnaire. Results showed general difficulties in inhibiting a response, rather than a specific impact of emotional context in preterm children. Compared with controls, these children exhibited more and longer button presses in a delay situation, as well as faster go reaction times associated with lower probability of inhibition in the stop-signal tasks. These difficulties reflected impulsivity and were associated with higher hyperactivity/inattention and conduct problems. Additionally, intrauterine growth restriction was found to be an additional perinatal risk factor for hyperactivity/inattention symptoms. These findings suggest that remaining inhibition difficulties in the preterm population at preadolescence could reveal increasing behavioral issues.

Cognitive-Behavioral Therapy for Depression in an Older Gay Man: A Clinical Case Study

PubMed Central

Satterfield, Jason M.; Crabb, Rebecca

2012-01-01

Although strong evidence supports cognitive-behavioral therapy for late-life depression and depression in racial and ethnic minorities, there are no empirical studies on the treatment of depression in older sexual minorities. Three distinct literatures were tapped to create a depression treatment protocol for an older gay male. Interventions were deduced from the late-life depression literature, culturally adapted CBT protocols for racial minorities, and the emerging social and developmental psychological theories for lesbian, gay, and bisexual populations. Specific treatment interventions, processes, and outcomes are described to illustrate how these literatures may be used to provide more culturally appropriate and effective health care for the growing, older sexual minority population. PMID:23144559

The Onset of Puberty: Effects on the Psychophysiology of Defensive and Appetitive Motivation

PubMed Central

Quevedo, Karina; Benning, Stephen D; Gunnar, Megan R; Dahl, Ronald E

2010-01-01

We examined puberty-specific effects on affect-related behavior and on the psychophysiology of defensive and appetitive motivation while controlling for age. Adolescents (N=94, ages=12 and 13 years), viewed 75 pictures (IAPS: pleasant, neutral and aversive) while listening to auditory probes. Startle response and postauricular (PA) reflex were collected as measures of defensive and appetitive motivation respectively. Pubertal status and measures of anxiety/stress reaction and sensation/thrill seeking were obtained. Mid/late pubertal adolescents showed enhanced startle amplitude across all picture valences. A puberty by valence interaction revealed that mid/late pubertal adolescents showed appetitive potentiation of the PA, while pre/early pubertal adolescents showed no modulation of the PA reflex. Mid/late pubertal adolescents also scored significantly higher on measures of sensation/thrill seeking than did their pre/early pubertal peers and puberty moderated the association between psychophysiology and behavioral measures, suggesting that it plays a role in reorganizing defensive and appetitive motivational systems. PMID:19144221

Eolian sediment responses to late Quaternary climate changes: Temporal and spatial patterns in the Sahara

USGS Publications Warehouse

Swezey, C.

2001-01-01

This paper presents a compilation of eolian-based records of late Quaternary climate changes in the Sahara. Although the data are relatively sparse, when viewed as a whole, they reveal a general pattern of widespread eolian sediment mobilization prior to 11,000 cal. years BP, eolian sediment stabilization from 11,000 to 5000 cal. years BP, and a return to widespread eolian sediment mobilization after 5000 cal. years BP. Furthermore, an eolian-based record from southern Tunisia reveals the existence of millennial-scale changes in eolian sediment behavior. These millennial-scale variations provide examples of eolian sediment responses to climate changes at a scale intermediate between seasonal and orbital ('Milankovitch') changes, and they are also coincident with abrupt atmospheric and oceanic changes. The general synchroneity of the eolian stratigraphic records and their coincidence with various oceanic and atmospheric changes suggest that global forcing mechanisms have influenced late Quaternary eolian sediment behavior in the Sahara. ?? 2001 Elsevier Science B.V.

Seeing the Partner: A Video Recall Study of Emotional Behavior in Same- and Mixed-Sex Late Adolescent Romantic Couples

ERIC Educational Resources Information Center

Darling, Nancy; Clarke, Sara A.

2009-01-01

Fifty-three college-aged same- and mixed-sex romantic couples (83% White, 63% female, mean age, 20.8) engaged in a video recall task in which they rated their own and their partners' behaviors and emotions. Females reported feeling more connected to partners and reported fewer negative behaviors than males. Females with male partners reported the…

Quality of Life and Its Predictors Among Children and Adolescents With Cancer.

PubMed

Pan, Hsien-Ting; Wu, Li-Min; Wen, Shu-Hui

Quality of life (QoL) increasingly is being assessed in pediatric patients with cancer. However, only a few studies focused on QoL predictors during and after treatment for pediatric patients with cancer. The aims of this study were to (1) assess differences of QoL, distress behavior, and fatigue among children and adolescents; (2) examine the relationship of distress behaviors, fatigue, and a variety of demographic factors to QoL; and (3) identify QoL predictors. A cross-sectional descriptive study involving 150 participants treated between 2012 and 2014 was conducted. All participants were given a diagnosis of cancer, ranged in age from 7 to 18 years, and had no developmental delay or mental illness. Three instruments including Pediatric Quality of Life, Distress Behaviors, and Multidimensional Fatigue Scale were administered. Adolescents aged 16 to 18 years reported lower school functioning and experienced more general and sleep/rest fatigue. Fatigue and distress behaviors were associated with a poorer QoL. Diagnosis at a younger age, greater time since diagnosis, and family structure were associated with a better QoL. General fatigue, relationship distress, family structure, and time since diagnosis were significant predictors of QoL, accounting for 64% of the total variance. Factors associated with a poorer QoL included fatigue, distress behaviors, and diagnosis at an older age. Less general fatigue and relationship distress, greater time since diagnosis, and living in nuclear family predicted a better QoL. Routinely evaluating fatigue and school functioning in pediatric patients with cancer is warranted, as well as developing educational programs to enhance the management of fatigue and relationship issues, especially for those who were given a diagnosis recently or for late adolescents.

Traumatic brain injury causes long-term behavioral changes related to region-specific increases of cerebral blood flow.

PubMed

Pöttker, Bruno; Stöber, Franziska; Hummel, Regina; Angenstein, Frank; Radyushkin, Konstantin; Goldschmidt, Jürgen; Schäfer, Michael K E

2017-12-01

Traumatic brain injury (TBI) is a leading cause of disability and death and survivors often suffer from long-lasting motor impairment, cognitive deficits, anxiety disorders and epilepsy. Few experimental studies have investigated long-term sequelae after TBI and relations between behavioral changes and neural activity patterns remain elusive. We examined these issues in a murine model of TBI combining histology, behavioral analyses and single-photon emission computed tomography (SPECT) imaging of regional cerebral blood flow (CBF) as a proxy for neural activity. Adult C57Bl/6N mice were subjected to unilateral cortical impact injury and investigated at early (15-57 days after lesion, dal) and late (184-225 dal) post-traumatic time points. TBI caused pronounced tissue loss of the parietal cortex and subcortical structures and enduring neurological deficits. Marked perilesional astro- and microgliosis was found at 57 dal and declined at 225 dal. Motor and gait pattern deficits occurred at early time points after TBI and improved over the time. In contrast, impaired performance in the Morris water maze test and decreased anxiety-like behavior persisted together with an increased susceptibility to pentylenetetrazole-induced seizures suggesting alterations in neural activity patterns. Accordingly, SPECT imaging of CBF indicated asymmetric hemispheric baseline neural activity patterns. In the ipsilateral hemisphere, increased baseline neural activity was found in the amygdala. In the contralateral hemisphere, homotopic to the structural brain damage, the hippocampus and distinct cortex regions displayed increased baseline neural activity. Thus, regionally elevated CBF along with behavioral alterations indicate that increased neural activity is critically involved in the long-lasting consequences of TBI.

Mating behavior of a flower-visiting longhorn beetle Zorion guttigerum (Westwood) (Coleoptera: Cerambycidae: Cerambycinae)

NASA Astrophysics Data System (ADS)

Wang, Qiao; Chen, Li-Yuan

2005-05-01

Long-range sex pheromones have been demonstrated for several cerambycid beetle species. Our field study on the mating behavior of Zorion guttigerum, on the basis of its temporal and spatial distributions on mating and feeding sites (flowers), and longevity, however, suggests that such pheromones are not used by this species. Plant characteristics rather than long-range sex pheromones may play an important role in bringing both sexes together. Adult activities on flowers occur exclusively during the day with two peaks, one around midday and the other in the late afternoon. Overall operational sex ratio is male-biased (≈1 ♀:1.5 ♂) but it becomes very highly male-biased (≈1 ♀:9 ♂) when mating and feeding activities decrease to the minimum in mid-afternoon, suggesting that females leave flowers to oviposit during that period of time. For cerambycid species whose females oviposit alone, and in which mating and oviposition occur on different plants or different plant parts, the operational sex ratio appears to vary significantly over time on the mating sites. The number and duration of pair-bondings also vary over time for Z. guttigerum. Fewer and shorter pair-bondings in the morning may suggest a strong sexual selection process. After ≈2 h of selection, both sexes tend to engage in longer pair-bondings and mate more times before females leave the mating sites in mid-afternoon. Details of the mating behavior are described here.

Mating behavior of a flower-visiting longhorn beetle Zorion guttigerum (Westwood) (Coleoptera: Cerambycidae: Cerambycinae).

PubMed

Wang, Qiao; Chen, Li-Yuan

2005-05-01

Long-range sex pheromones have been demonstrated for several cerambycid beetle species. Our field study on the mating behavior of Zorion guttigerum, on the basis of its temporal and spatial distributions on mating and feeding sites (flowers), and longevity, however, suggests that such pheromones are not used by this species. Plant characteristics rather than long-range sex pheromones may play an important role in bringing both sexes together. Adult activities on flowers occur exclusively during the day with two peaks, one around midday and the other in the late afternoon. Overall operational sex ratio is male-biased ( approximately 1 female symbol:1.5 male symbol) but it becomes very highly male-biased ( approximately 1 female symbol:9 male symbol) when mating and feeding activities decrease to the minimum in mid-afternoon, suggesting that females leave flowers to oviposit during that period of time. For cerambycid species whose females oviposit alone, and in which mating and oviposition occur on different plants or different plant parts, the operational sex ratio appears to vary significantly over time on the mating sites. The number and duration of pair-bondings also vary over time for Z. guttigerum. Fewer and shorter pair-bondings in the morning may suggest a strong sexual selection process. After approximately 2 h of selection, both sexes tend to engage in longer pair-bondings and mate more times before females leave the mating sites in mid-afternoon. Details of the mating behavior are described here.

Development of Constructivist Theory of Mind from Middle Childhood to Early Adulthood and Its Relation to Social Cognition and Behavior

PubMed Central

Weimer, Amy A.; Parault Dowds, Susan J.; Fabricius, William V.; Schwanenflugel, Paula J.; Suh, Go Woon

2016-01-01

Two studies examined the development of constructivist theory of mind (ToM) during late childhood and early adolescence. In Study 1 a new measure was developed to assess participants’ understanding of the interpretive and constructive processes embedded in memory, comprehension, attention, comparison, planning, and inference. Using this measure, Study 2 tested a mediational model in which prosocial reasoning about conflict mediated the relation between constructivist ToM and behavior problems in high school. Results showed that the onset of constructivist ToM occurs between late childhood and early adolescence, and that adolescents who have more advanced constructivist ToM have more prosocial reasoning about conflict, which in turn mediated the relation with fewer serious behavior problems in high school, after controlling for academic performance and sex. In both studies, females showed more advanced constructivist ToM than males in high school. PMID:27821294

Influence of parental alcohol-related attitudes, behavior and parenting styles on alcohol use in late and very late adolescence.

PubMed

Stafström, Martin

2014-01-01

Parents influence adolescent drinking behavior, but to what extent does this association diminish with age, however? The cross-sectional data was drawn from the Scania drug use survey 2007, consisting of 4,828 secondary education students in the 9th and 11th grade. The age- and gender-adjusted findings indicate that having parents who are consenting to alcohol use (OR 1.4), having been provided with alcohol by one's parents (OR 1.8), having parents with an authoritarian (OR 1.5) or neglectful (OR 2.1) parenting style, and having parents who both have a university degree (OR 1.3) were factors significantly associated with monthly heavy episodic drinking. These findings lead to the conclusion that parenting styles as well as parental attitudes and behaviors are important throughout the high school years. Thus, prevention targeting parents should emphasize both these domains. © 2014 S. Karger AG, Basel.

Understanding Reckless Behavior in Adolescence.

ERIC Educational Resources Information Center

Arnett, Jeffrey

Briefly described is a theory of reckless behavior in adolescence that includes cognitive and biological factors. Discussion focuses on several factors: the adolescent's egocentric personal fable--the adolescent conviction that his/her thoughts and feelings are unique, the personality trait of sensation seeking, the fact that by their late 20s or…

Australian Adolescents' Perceptions of Health-Related Risks.

ERIC Educational Resources Information Center

Moore, Susan M.; Rosenthal, Doreen A.

1992-01-01

Evaluates the perceptions of adolescents (n=189) of their risks and ascertains the relationship between risk perception and actual risky behavior in five areas: AIDS, STDs, serious car accidents, lung cancer, and skin cancer. Results indicated that although late-adolescent students underestimated risk behavior, they were able to make judgments…

The Generality of Deviance in Late Adolescence and Early Adulthood.

ERIC Educational Resources Information Center

Osgood, D. Wayne; And Others

1988-01-01

Examination of self-reports by high school seniors about substance abuse, dangerous driving, and other criminal behavior demonstrates that a relatively stable general involvement in deviance accounted for virtually all association between different types of deviance, but the stability of each behavior could be explained only by equally important…

Temporal Withdrawal Behaviors in an Educational Policy Context

ERIC Educational Resources Information Center

Rosenblatt, Zehava; Shapira-Lishchinsky, Orly

2017-01-01

Purpose: The purpose of this paper is to investigate the differential relations between two teacher withdrawal behaviors: work absence and lateness, and two types of school ethics: organizational justice (distributive, procedural) and ethical climate (formal, caring), all in the context of school turbulent environment. Design/methodology/approach:…

Helping Others? The Effects of Childhood Poverty and Family Instability on Prosocial Behavior.

ERIC Educational Resources Information Center

Lichter, Daniel T.; Shanahan, Michael J.; Gardner, Erica L.

2002-01-01

Examines the relationship between poverty and family instability during childhood on prosocial behavior (volunteerism) during late adolescence. Data from the National Longitudinal Survey of Youth (NLSY), including mother and family records, indicate that adolescents, particularly males, from single parent families are less likely than those from…

Trajectories of psychopathology and risky behaviors associated with childhood abuse and neglect in low-income urban African American girls.

PubMed

Wilson, Helen W; Samuelson, Sarah L; Staudenmeyer, Anna H; Widom, Cathy Spatz

2015-07-01

The current study examined patterns of psychopathology, drug and alcohol use, and sexual behavior associated with childhood abuse and neglect in a high-risk sample of low-income African American girls seeking mental health treatment. Participants (N=177) were African American girls recruited from mental health clinics serving low-income communities in Chicago, IL and followed over six waves of data collection (T1-T6) reflecting early (mean age 14) to late (mean age 17) adolescence. Child abuse and neglect history was determined from adolescent and caregiver reports. Latent curve modeling examined patterns of internalizing and externalizing psychopathology, drug and alcohol use, sexual experience, and risky sexual behavior reported by girls and associations with reported child abuse and neglect. Overall, these trajectories indicated a decrease in internalizing and externalizing symptoms, stability of drug and alcohol use, and an increase in sexual experience and risky sexual behaviors over time. Child abuse and neglect was associated with increased internalizing symptoms and sexual experience at baseline and with externalizing symptoms and risky sexual behavior both at baseline and the final point. Child abuse and neglect was not significantly associated with alcohol or drug use. This study adds to the literature on the long-term consequences of child abuse and neglect by demonstrating patterns of psychopathology and risky behavior that persist over time in a high-risk group of girls with self or parent reported histories of abuse and neglect. Interventions that address externalizing problems and health risk behaviors may be of particular importance for this population. Copyright © 2015. Published by Elsevier Ltd.

Interpersonal influences on late adolescent girls' and boys' disordered eating.

PubMed

Shomaker, Lauren B; Furman, Wyndol

2009-04-01

Perceived socio-cultural pressure to be thin has an important impact on disordered eating during early and middle adolescence, but less is known about late adolescence. Most prospective studies included only girls, and less is known about the influence on boys. This study investigated interpersonal influences on changes in late adolescent boys' and girls' symptoms of disordered eating over one year. Participants were a community sample of late adolescents 16-19 years of age (N=199; 49.75% girls), their mothers, and friends. Structural equation modeling revealed that interpersonal pressure to be thin and criticism about appearance predicted increases in disordered eating over time. Late adolescents', mothers' and friends' reports of pressure were associated with disordered eating at Time 1 and Time 2. Further, adolescents' perceptions and friends' reports of pressure to be thin predicted changes in disordered eating over time. Findings underscore the significance of interpersonal relationships for disordered eating during late adolescence in both girls and boys.

Interpersonal Influences on Late Adolescent Girls’ and Boys’ Disordered Eating

PubMed Central

Shomaker, Lauren B.; Furman, Wyndol

2009-01-01

Perceived socio-cultural pressure to be thin has an important impact on disordered eating during early and middle adolescence, but less is known about late adolescence. Most prospective studies included only girls, and less is known about the influence on boys. This study investigated interpersonal influences on changes in late adolescent boys’ and girls’ symptoms of disordered eating over one year. Participants were a community sample of late adolescents 16–19 years of age (N = 199; 49.75% girls), their mothers, and friends. Structural equation modeling revealed that interpersonal pressure to be thin and criticism about appearance predicted increases in disordered eating over time. Late adolescents’, mothers’ and friends’ reports of pressure were associated with disordered eating at Time 1 and Time 2. Further, adolescents’ perceptions and friends’ reports of pressure to be thin predicted changes in disordered eating over time. Findings underscore the significance of interpersonal relationships for disordered eating during late adolescence in both girls and boys. PMID:19447351

Extrinsic Embryonic Sensory Stimulation Alters Multimodal Behavior and Cellular Activation

PubMed Central

Markham, Rebecca G.; Shimizu, Toru; Lickliter, Robert

2009-01-01

Embryonic vision is generated and maintained by spontaneous neuronal activation patterns, yet extrinsic stimulation also sculpts sensory development. Because the sensory and motor systems are interconnected in embryogenesis, how extrinsic sensory activation guides multimodal differentiation is an important topic. Further, it is unknown whether extrinsic stimulation experienced near sensory sensitivity onset contributes to persistent brain changes, ultimately affecting postnatal behavior. To determine the effects of extrinsic stimulation on multimodal development, we delivered auditory stimulation to bobwhite quail groups during early, middle, or late embryogenesis, and then tested postnatal behavioral responsiveness to auditory or visual cues. Auditory preference tendencies were more consistently toward the conspecific stimulus for animals stimulated during late embryogenesis. Groups stimulated during middle or late embryogenesis showed altered postnatal species-typical visual responsiveness, demonstrating a persistent multimodal effect. We also examined whether auditory-related brain regions are receptive to extrinsic input during middle embryogenesis by measuring postnatal cellular activation. Stimulated birds showed a greater number of ZENK-immunopositive cells per unit volume of brain tissue in deep optic tectum, a midbrain region strongly implicated in multimodal function. We observed similar results in the medial and caudomedial nidopallia in the telencephalon. There were no ZENK differences between groups in inferior colliculus or in caudolateral nidopallium, avian analog to prefrontal cortex. To our knowledge, these are the first results linking extrinsic stimulation delivered so early in embryogenesis to changes in postnatal multimodal behavior and cellular activation. The potential role of competitive interactions between the sensory and motor systems is discussed. PMID:18777564

Strength of figure-ground activity in monkey primary visual cortex predicts saccadic reaction time in a delayed detection task.

PubMed

Supèr, Hans; Lamme, Victor A F

2007-06-01

When and where are decisions made? In the visual system a saccade, which is a fast shift of gaze toward a target in the visual scene, is the behavioral outcome of a decision. Current neurophysiological data and reaction time models show that saccadic reaction times are determined by a build-up of activity in motor-related structures, such as the frontal eye fields. These structures depend on the sensory evidence of the stimulus. Here we use a delayed figure-ground detection task to show that late modulated activity in the visual cortex (V1) predicts saccadic reaction time. This predictive activity is part of the process of figure-ground segregation and is specific for the saccade target location. These observations indicate that sensory signals are directly involved in the decision of when and where to look.

Weekend sun protection and sunburn in Australia trends (1987-2002) and association with SunSmart television advertising.

PubMed

Dobbinson, Suzanne J; Wakefield, Melanie A; Jamsen, Kris M; Herd, Natalie L; Spittal, Matthew J; Lipscomb, John E; Hill, David J

2008-02-01

The Australian state of Victoria has run a population-based skin cancer prevention program called SunSmart since 1988, incorporating substantial public education efforts and environmental change strategies. Trends over 15 years in behavioral risk factors for skin cancer were examined in a population exposed to the SunSmart program. Whether outcomes were associated with extent of SunSmart television advertising was then assessed. In nine cross-sectional surveys from 1987 to 2002, 11,589 adults were interviewed by telephone about their sun exposure and sun protection during outdoor activities on summer weekends. Analyses completed in 2007 adjusted for ambient temperature and ultraviolet radiation. Sun protection and sunburn show substantial general improvement over time, but have stalled in recent years. Use of hats and sunscreens significantly increased over time and peaked during the mid to late 1990s, compared with the pre-SunSmart baseline. The mean proportion of unprotected skin was reduced and was lowest in the summer of 1997-1998. Summer sunburn incidence declined over time and was 9.1% in 2002, almost half baseline (OR=0.53; 95% CI=0.39-0.73). Higher exposure to SunSmart advertising in the 4 weeks before the interview increased: (1) preference for no tan, (2) hat and sunscreen use, and (3) proportion of body surface protected from the sun. The general improvement in sun-protective behaviors over time highlight that a population's sun-protective behaviors are amenable to change. Population-based prevention programs incorporating substantial television advertising campaigns into the mix of strategies may be highly effective in improving a population's sun-protective behaviors.

Open EFTs, IR effects & late-time resummations: systematic corrections in stochastic inflation

DOE PAGES

Burgess, C. P.; Holman, R.; Tasinato, G.

2016-01-26

Though simple inflationary models describe the CMB well, their corrections are often plagued by infrared effects that obstruct a reliable calculation of late-time behaviour. Here we adapt to cosmology tools designed to address similar issues in other physical systems with the goal of making reliable late-time inflationary predictions. The main such tool is Open EFTs which reduce in the inflationary case to Stochastic Inflation plus calculable corrections. We apply this to a simple inflationary model that is complicated enough to have dangerous IR behaviour yet simple enough to allow the inference of late-time behaviour. We find corrections to standard Stochasticmore » Inflationary predictions for the noise and drift, and we find these corrections ensure the IR finiteness of both these quantities. The late-time probability distribution, P(Φ), for super-Hubble field fluctuations are obtained as functions of the noise and drift and so these too are IR finite. We compare our results to other methods (such as large-N models) and find they agree when these models are reliable. In all cases we can explore in detail we find IR secular effects describe the slow accumulation of small perturbations to give a big effect: a significant distortion of the late-time probability distribution for the field. But the energy density associated with this is only of order H 4 at late times and so does not generate a dramatic gravitational back-reaction.« less

Open EFTs, IR effects & late-time resummations: systematic corrections in stochastic inflation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burgess, C. P.; Holman, R.; Tasinato, G.

Though simple inflationary models describe the CMB well, their corrections are often plagued by infrared effects that obstruct a reliable calculation of late-time behaviour. Here we adapt to cosmology tools designed to address similar issues in other physical systems with the goal of making reliable late-time inflationary predictions. The main such tool is Open EFTs which reduce in the inflationary case to Stochastic Inflation plus calculable corrections. We apply this to a simple inflationary model that is complicated enough to have dangerous IR behaviour yet simple enough to allow the inference of late-time behaviour. We find corrections to standard Stochasticmore » Inflationary predictions for the noise and drift, and we find these corrections ensure the IR finiteness of both these quantities. The late-time probability distribution, P(Φ), for super-Hubble field fluctuations are obtained as functions of the noise and drift and so these too are IR finite. We compare our results to other methods (such as large-N models) and find they agree when these models are reliable. In all cases we can explore in detail we find IR secular effects describe the slow accumulation of small perturbations to give a big effect: a significant distortion of the late-time probability distribution for the field. But the energy density associated with this is only of order H 4 at late times and so does not generate a dramatic gravitational back-reaction.« less

Analytically Solvable Model of Spreading Dynamics with Non-Poissonian Processes

NASA Astrophysics Data System (ADS)

Jo, Hang-Hyun; Perotti, Juan I.; Kaski, Kimmo; Kertész, János

2014-01-01

Non-Poissonian bursty processes are ubiquitous in natural and social phenomena, yet little is known about their effects on the large-scale spreading dynamics. In order to characterize these effects, we devise an analytically solvable model of susceptible-infected spreading dynamics in infinite systems for arbitrary inter-event time distributions and for the whole time range. Our model is stationary from the beginning, and the role of the lower bound of inter-event times is explicitly considered. The exact solution shows that for early and intermediate times, the burstiness accelerates the spreading as compared to a Poisson-like process with the same mean and same lower bound of inter-event times. Such behavior is opposite for late-time dynamics in finite systems, where the power-law distribution of inter-event times results in a slower and algebraic convergence to a fully infected state in contrast to the exponential decay of the Poisson-like process. We also provide an intuitive argument for the exponent characterizing algebraic convergence.

Effects of Sex and Mild Intrainsult Hypothermia on Neuropathology and Neural Reorganization following Neonatal Hypoxic Ischemic Brain Injury in Rats

PubMed Central

Smith, Amanda L.; Rosenkrantz, Ted S.; Fitch, R. Holly

2016-01-01

Hypoxia ischemia (HI) is a recognized risk factor among late-preterm infants, with HI events leading to varied neuropathology and cognitive/behavioral deficits. Studies suggest a sex difference in the incidence of HI and in the severity of subsequent behavioral deficits (with better outcomes in females). Mechanisms of a female advantage remain unknown but could involve sex-specific patterns of compensation to injury. Neuroprotective hypothermia is also used to ameliorate HI damage and attenuate behavioral deficits. Though currently prescribed only for HI in term infants, cooling has potential intrainsult applications to high-risk late-preterm infants as well. To address this important clinical issue, we conducted a study using male and female rats with a postnatal (P) day 7 HI injury induced under normothermic and hypothermic conditions. The current study reports patterns of neuropathology evident in postmortem tissue. Results showed a potent benefit of intrainsult hypothermia that was comparable for both sexes. Findings also show surprisingly different patterns of compensation in the contralateral hemisphere, with increases in hippocampal thickness in HI females contrasting reduced thickness in HI males. Findings provide a framework for future research to compare and contrast mechanisms of neuroprotection and postinjury plasticity in both sexes following a late-preterm HI insult. PMID:27042359

Behavioral decline and premature lethality upon pan-neuronal ferritin overexpression in Drosophila infected with a virulent form of Wolbachia

PubMed Central

Kosmidis, Stylianos; Missirlis, Fanis; Botella, Jose A.; Schneuwly, Stephan; Rouault, Tracey A.; Skoulakis, Efthimios M. C.

2014-01-01

Iron is required for organismal growth. Therefore, limiting iron availability may be a key part of the host’s innate immune response to various pathogens, for example, in Drosophila infected with Zygomycetes. One way the host can transiently reduce iron bioavailability is by ferritin overexpression. To study the effects of neuronal-specific ferritin overexpression on survival and neurodegeneration we generated flies simultaneously over-expressing transgenes for both ferritin subunits in all neurons. We used two independent recombinant chromosomes bearing UAS-Fer1HCH, UAS-Fer2LCH transgenes and obtained qualitatively different levels of late-onset behavioral and lifespan declines. We subsequently discovered that one parental strain had been infected with a virulent form of the bacterial endosymbiont Wolbachia, causing widespread neuronal apoptosis and premature death. This phenotype was exacerbated by ferritin overexpression and was curable by antibiotic treatment. Neuronal ferritin overexpression in uninfected flies did not cause evident neurodegeneration but resulted in a late-onset behavioral decline, as previously reported for ferritin overexpression in glia. The results suggest that ferritin overexpression in the central nervous system of flies is tolerated well in young individuals with adverse manifestations appearing only late in life or under unrelated pathophysiological conditions. PMID:24772084

20 CFR 349.4 - Late completion of timely investigation.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true Late completion of timely investigation. 349.4 Section 349.4 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD UNEMPLOYMENT INSURANCE ACT FINALITY OF DECISIONS REGARDING UNEMPLOYMENT AND SICKNESS INSURANCE BENEFITS § 349.4 Late...

20 CFR 349.4 - Late completion of timely investigation.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true Late completion of timely investigation. 349.4 Section 349.4 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD UNEMPLOYMENT INSURANCE ACT FINALITY OF DECISIONS REGARDING UNEMPLOYMENT AND SICKNESS INSURANCE BENEFITS § 349.4 Late...

Visual short-term memory load modulates the early attention and perception of task-irrelevant emotional faces

PubMed Central

Yang, Ping; Wang, Min; Jin, Zhenlan; Li, Ling

2015-01-01

The ability to focus on task-relevant information, while suppressing distraction, is critical for human cognition and behavior. Using a delayed-match-to-sample (DMS) task, we investigated the effects of emotional face distractors (positive, negative, and neutral faces) on early and late phases of visual short-term memory (VSTM) maintenance intervals, using low and high VSTM loads. Behavioral results showed decreased accuracy and delayed reaction times (RTs) for high vs. low VSTM load. Event-related potentials (ERPs) showed enhanced frontal N1 and occipital P1 amplitudes for negative faces vs. neutral or positive faces, implying rapid attentional alerting effects and early perceptual processing of negative distractors. However, high VSTM load appeared to inhibit face processing in general, showing decreased N1 amplitudes and delayed P1 latencies. An inverse correlation between the N1 activation difference (high-load minus low-load) and RT costs (high-load minus low-load) was found at left frontal areas when viewing negative distractors, suggesting that the greater the inhibition the lower the RT cost for negative faces. Emotional interference effect was not found in the late VSTM-related parietal P300, frontal positive slow wave (PSW) and occipital negative slow wave (NSW) components. In general, our findings suggest that the VSTM load modulates the early attention and perception of emotional distractors. PMID:26388763

Motherhood and infant contact regulate neuroplasticity in the serotonergic midbrain dorsal raphe.

PubMed

Holschbach, M Allie; Lonstein, Joseph S

2017-02-01

The adult brain shows remarkable neuroplasticity in response to hormones and the socioemotional modifications that they influence. In females with reproductive and maternal experience, this neuroplasticity includes the birth and death of cells in several forebrain regions involved in maternal caregiving and postpartum affective state. Such plasticity in midbrain sites critical for these behavioral and emotional processes has never been examined, though. By visualizing bromodeoxyuridine (BrdU) to label mitotic cells, NeuroD for neuronal precursors, and TUNEL to identify dying cells, we found that the midbrain dorsal raphe nucleus (DR, the source of most ascending serotoninergic projections) exhibited significant neuroplasticity in response to motherhood. Specifically, BrdU analyses revealed that DR newborn cell survival (but not proliferation) was regulated by reproductive state, such that cells born early postpartum were less likely to survive 12 days to reach the late postpartum period compared to cells born during late pregnancy that survived 12 days to reach the early postpartum period. Many of the surviving cells in the DR were NeuN immunoreactive, suggesting a neuronal phenotype. Consistent with these findings, late postpartum rats had fewer NeuroD-immunoreactive DR cells than early postpartum rats. Maternal experience contributed to the late postpartum reduction in DR newborn cell survival because removing the litter at parturition increased cell survival as well as reduced cell death. Unlike cytogenesis in the maternal hippocampus, which is reduced by circulating glucocorticoids, DR newborn cell survival was unaffected by postpartum adrenalectomy. These effects of reproductive state and motherhood on DR plasticity were associated with concurrent changes in DR levels of serotonin's precursor, 5-HTP, and its metabolite, 5-HIAA. Our results demonstrate for the first time that cytogenesis occurs in the midbrain DR of any adult mammal, that DR plasticity is influenced by female reproductive state and maternal experience, and that this plasticity is accompanied by changes in DR serotonergic function. Because serotonin is critical for postpartum caregiving behaviors and maternal affective state, plasticity in the DR may contribute to the neurochemical changes necessary for successful motherhood. Copyright © 2016 Elsevier Ltd. All rights reserved.

Continuity of Genetic and Environmental Influences on Cognition across the Life Span: A Meta-Analysis of Longitudinal Twin and Adoption Studies

PubMed Central

Tucker-Drob, Elliot M.; Briley, Daniel A.

2014-01-01

The longitudinal rank-order stability of cognitive ability increases dramatically over the lifespan. Multiple theoretical perspectives have proposed that genetic and/or environmental mechanisms underlie the longitudinal stability of cognition, and developmental trends therein. However, the patterns of stability of genetic and environmental influences on cognition over the lifespan largely remain poorly understood. We searched for longitudinal studies of cognition that reported raw genetically-informative longitudinal correlations or parameter estimates from longitudinal behavior genetic models. We identified 150 combinations of time points and measures from 15 independent longitudinal samples. In total, longitudinal data came from 4,538 monozygotic twin pairs raised together, 7,777 dizygotic twin pairs raised together, 34 monozygotic twin pairs raised apart, 78 dizygotic twin pairs raised apart, 141 adoptive sibling pairs, and 143 non-adoptive sibling pairs, ranging in age from infancy through late adulthood. At all ages, cross-time genetic correlations and shared environmental correlations were substantially larger than cross-time nonshared environmental correlations. Cross-time correlations for genetic and shared environmental components were low during early childhood, increased sharply over child development, and remained relatively high from adolescence through late adulthood. Cross-time correlations for nonshared environmental components were low across childhood and increased gradually to moderate magnitudes in adulthood. Increasing phenotypic stability over child development was almost entirely mediated by genetic factors. Time-based decay of genetic and shared environmental stability was more pronounced earlier in child development. Results are interpreted in reference to theories of gene-environment interaction and correlation. PMID:24611582

A New Tephrochronology for Early Diverse Stone Tool Technologies and Long-Distance Raw Material Transport in the Middle-Late Pleistocene Kapthurin Formation, East Africa.

NASA Astrophysics Data System (ADS)

Blegen, N.; Jicha, B.

2017-12-01

The Middle to Late Pleistocene (780-10 ka) of East Africa records significant behavioral change, the earliest fossils of Homo sapiens and the dispersals of our species across and out of Africa. Studying human evolution in the Middle to Late Pleistocene thus requires an extensive and precise chronology relating the appearances of various behaviors preserved in archaeological sequences to aspects of hominin biology and evidence of past environments preserved in the fossils and geological sequences. Tephrochronology provides the chronostratigraphic resolution to achieve this through correlation and dating of volcanic ashes. The tephrochronology of the Kapthurin Formation presented here, based on tephra correlations and 40Ar/ 39Ar dates, provides new ages between 396.3 ± 3.4 ka and 465.3 ± 1.0 ka for nine sites showing some of the earliest evidence of diverse blade and Levallois methods of core reduction. These are >110 kyr older than previously known in East Africa. New 40Ar/ 39Ar dates provide a refined age of 222.5 ± 0.6 ka for early evidence of long-distance obsidian transport at the Sibilo School Road Site. Long-distance tephra correlation between the Baringo and Lake Victoria basins also provides a new date of 100 ka for the Middle Stone Age site of Keraswanin. By providing new or older dates for 11 sites containing several important aspects of hominin behavior and extending the chronology of the Kapthurin Formation forward by 130,000 years, the tephrochronology presented here contributes one of the longest and most refined chronostratigraphic frameworks relevant to modern human evolution. In conjunction with recent archaeological and paleoenvironmental data, this tephrochronology provides the foundation to understand the process of modern human behavioral evolution through the East African Middle and Late Pleistocene as it relates to biological and paleoenvironmental circumstances.

Electrophysiological evidence for women superiority on unfamiliar face processing.

PubMed

Sun, Tianyi; Li, Lin; Xu, Yuanli; Zheng, Li; Zhang, Weidong; Zhou, Fanzhi Anita; Guo, Xiuyan

2017-02-01

Previous research has reported that women superiority on face recognition tasks, taking sex difference in accuracy rates as major evidence. By appropriately modifying experimental tasks and examining reaction time as behavioral measure, it was possible to explore which stage of face processing contributes to womens' superiority. We used a modified delayed matching-to-sample task to investigate the time course characteristics of face recognition by ERP, for both men and women. In each trial, participants matched successively presented faces to samples (target faces) by key pressing. It was revealed that women were more accurate and faster than men on the task. ERP results showed that compared to men, women had shorter peak latencies of early components P100 and N170, as well as larger mean amplitude of the late positive component P300. Correlations between P300 mean amplitudes and RTs were found for both sexes. Besides, reaction times of women but not men were positively correlated with N170 latencies. In general, we provided further evidence for women superiority on face recognition in both behavioral and neural aspects. Copyright © 2016 Elsevier Ireland Ltd and Japan Neuroscience Society. All rights reserved.

Divergent phenological response to hydroclimate variability in forested mountain watersheds.

PubMed

Hwang, Taehee; Band, Lawrence E; Miniat, Chelcy F; Song, Conghe; Bolstad, Paul V; Vose, James M; Love, Jason P

2014-08-01

Mountain watersheds are primary sources of freshwater, carbon sequestration, and other ecosystem services. There is significant interest in the effects of climate change and variability on these processes over short to long time scales. Much of the impact of hydroclimate variability in forest ecosystems is manifested in vegetation dynamics in space and time. In steep terrain, leaf phenology responds to topoclimate in complex ways, and can produce specific and measurable shifts in landscape forest patterns. The onset of spring is usually delayed at a specific rate with increasing elevation (often called Hopkins' Law; Hopkins, 1918), reflecting the dominant controls of temperature on greenup timing. Contrary with greenup, leaf senescence shows inconsistent trends along elevation gradients. Here, we present mechanisms and an explanation for this variability and its significance for ecosystem patterns and services in response to climate. We use moderate-resolution imaging spectro-radiometer (MODIS) Normalized Difference Vegetation Index (NDVI) data to derive landscape-induced phenological patterns over topoclimate gradients in a humid temperate broadleaf forest in southern Appalachians. These phenological patterns are validated with different sets of field observations. Our data demonstrate that divergent behavior of leaf senescence with elevation is closely related to late growing season hydroclimate variability in temperature and water balance patterns. Specifically, a drier late growing season is associated with earlier leaf senescence at low elevation than at middle elevation. The effect of drought stress on vegetation senescence timing also leads to tighter coupling between growing season length and ecosystem water use estimated from observed precipitation and runoff generation. This study indicates increased late growing season drought may be leading to divergent ecosystem response between high and low elevation forests. Landscape-induced phenological patterns are easily observed over wide areas and may be used as a unique diagnostic for sources of ecosystem vulnerability and sensitivity to hydroclimate change. © 2014 John Wiley & Sons Ltd.

Turbulence evolution and transport behavior during current ramp-up in ITER-like plasmas on DIII-D

DOE PAGES

McKee, George R.; Austin, Max E.; Boedo, Jose A.; ...

2017-07-12

Low-wavenumber density fluctuations exhibit unique characteristics during the current ramp-up phase of ITER-like discharges that can partially explain the challenges of correctly modeling transport behavior and predicting global plasma parameters during this period. A strong interaction takes place between the evolving transport, safety factor (q) and kinetic profiles as well as the appearance and evolution of low-order rational surfaces. Density fluctuations from 0.75 < ρ < 0.9 are transiently reduced to exceptionally low levels during early times and from 0.8 < ρ < 0.9 at late times in the ramp-up in a manner that is different from behavior observed duringmore » steady-state plasma conditions with similar values of q 95. Turbulence is suppressed as low-order-rational q-surfaces enter the plasma; the local electron temperature likewise exhibits transient increases during these periods of reduced fluctuations indicating changes in transport that impact temperature and consequently the evolution of current density and plasma inductance. These observations can explain discrepancies between CORSICA modelling and the higher electron temperature found previously over the outer half radius. Comparison of turbulence properties with time-varying linear growth rates with GYRO and GENE demonstrate qualitative consistency with measured fluctuation levels, but calculations don’t exhibit reduced growth rates near low-order rational surfaces, which is inconsistent with experimental observations. Here, this indicates a mechanism that can contribute to reconciling observed turbulence behavior with transport models, allowing for the development of more accurate predictive tools.« less

Turbulence evolution and transport behavior during current ramp-up in ITER-like plasmas on DIII-D

NASA Astrophysics Data System (ADS)

McKee, G. R.; Austin, M.; Boedo, J.; Bravenec, R.; Holland, C.; Jackson, G.; Luce, T. C.; Rhodes, T. L.; Rudakov, D.; Wang, G.; Yan, Z.; Zeng, L.; Zhao, Y.

2017-08-01

Low-wavenumber density fluctuations exhibit unique characteristics during the current ramp-up phase of ITER-like discharges that can partially explain the challenges of correctly modeling transport behavior and predicting global plasma parameters during this period. A strong interaction takes place between the evolving transport, safety factor (q) and kinetic profiles as well as the appearance and evolution of low-order rational surfaces. Density fluctuations from 0.75  <  ρ  <  0.9 are transiently reduced to exceptionally low levels during early times and from 0.8  <  ρ  <  0.9 at late times in the ramp-up in a manner that is different from behavior observed during steady-state plasma conditions with similar values of q 95. Turbulence is suppressed as low-order-rational q-surfaces enter the plasma; the local electron temperature likewise exhibits transient increases during these periods of reduced fluctuations indicating changes in transport that impact temperature and consequently the evolution of current density and plasma inductance. These observations can explain discrepancies between CORSICA modelling and the higher electron temperature found previously over the outer half radius. Comparison of turbulence properties with time-varying linear growth rates with GYRO and GENE demonstrate qualitative consistency with measured fluctuation levels, but calculations don’t exhibit reduced growth rates near low-order rational surfaces, which is inconsistent with experimental observations. This indicates a mechanism that can contribute to reconciling observed turbulence behavior with transport models, allowing for the development of more accurate predictive tools.

Is Executive Cognitive Function Associated with Youth Gambling?

PubMed Central

Brodsky, Nancy L.; Brown, Caitlin A.; McKenna, Kathleen A.; Giannetta, Joan M.; Yang, Wei; Romer, Daniel; Hurt, Hallam

2011-01-01

Our objectives for this report were to identify trajectories of youth gambling behavior, and to examine their relation to executive cognitive function (ECF) and associated problem behaviors. Philadelphia school children, enrolled at ages 10–12 years (n = 387; 49% male), completed three annual assessments of risk behaviors, ECF, impulsivity, problem behaviors and demographics. Across ages 10–15 years, using methods from Nagin et al., two groups were identified: Early Gamblers (n = 111) initiated early and continued in later assessments, and Later Gamblers (n = 276) initiated at later ages and gambled less. Betting money on cards and sports were the most frequently reported gambling behaviors. Using gambling group as outcome, final backward selection logistic regression model showed Early Gamblers are more likely male (P = 0.001), report more active coping (P = 0.042), impulsive behaviors (P ≤ 0.008), and have friends who gamble (P = 0.001). Groups were similar in ECF, parental monitoring, marital status, SES, and race. Early Gamblers had higher incidence of problem behaviors and drug use (all P ≤ 0.006). Two gambling groups were identified in early adolescence with Early Gamblers showing higher levels of impulsivity and comorbid problems but similar levels of ECF compared to Late Gamblers. As more gambling groups are identified through later adolescence, ECF may emerge as a relevant precursor of problem gambling at this later time. PMID:21698342

Is executive cognitive function associated with youth gambling?

PubMed

Betancourt, Laura M; Brodsky, Nancy L; Brown, Caitlin A; McKenna, Kathleen A; Giannetta, Joan M; Yang, Wei; Romer, Daniel; Hurt, Hallam

2012-06-01

Our objectives for this report were to identify trajectories of youth gambling behavior, and to examine their relation to executive cognitive function (ECF) and associated problem behaviors. Philadelphia school children, enrolled at ages 10-12 years (n = 387; 49% male), completed three annual assessments of risk behaviors, ECF, impulsivity, problem behaviors and demographics. Across ages 10-15 years, using methods from Nagin et al., two groups were identified: Early Gamblers (n = 111) initiated early and continued in later assessments, and Later Gamblers (n = 276) initiated at later ages and gambled less. Betting money on cards and sports were the most frequently reported gambling behaviors. Using gambling group as outcome, final backward selection logistic regression model showed Early Gamblers are more likely male (P = 0.001), report more active coping (P = 0.042), impulsive behaviors (P ≤ 0.008), and have friends who gamble (P = 0.001). Groups were similar in ECF, parental monitoring, marital status, SES, and race. Early Gamblers had higher incidence of problem behaviors and drug use (all P ≤ 0.006). Two gambling groups were identified in early adolescence with Early Gamblers showing higher levels of impulsivity and comorbid problems but similar levels of ECF compared to Late Gamblers. As more gambling groups are identified through later adolescence, ECF may emerge as a relevant precursor of problem gambling at this later time.

A Comparison of the Behavioral and Psychological Symptoms of Dementia (BPSD) in Early-Onset and Late-Onset Alzheimer’s Disease - A Study from South East Asia (Kashmir, India)

PubMed Central

Mushtaq, Raheel; Pinto, Charles; Hussain, Arshad; Shoib, Sheikh; Shah, Tabindah; Shah, Sahil; Manzoor, Mushbiq; Bhat, Mudassir; Arif, Tasleem

2016-01-01

Background A gradual increase in the longevity due to advancement of treatment modalities and a subsequent surge in elderly population in India have led to a growing curiosity in the geriatric age group with Alzheimer’s disease (AD). Behavioral and psychological symptoms of dementia (BPSD) represent epiphenomena of AD. However, no comprehensive study has been carried out in South East Asia (Kashmir, India), to assess the behavioral and psychological symptoms in subtypes of AD. Objectives The purpose of this study was to assess BPSD in early-onset Alzheimer’s disease (EOAD) and late-onset Alzheimer’s disease (LOAD). Material and Methods The study was conducted in the Memory clinic of the postgraduate department of psychiatry, Government Medical College, Kashmir, India from January 2012 to March 2014. The diagnosis of AD patients was done according to NINCDS-ADRDA criteria. A total of 80 patients of AD were screened (40 with age of onset less than 65, and 40 with age of onset greater than 64). Neuropsychiatric inventory (NPI) was the instrument used for evaluating symptoms of BPSD. The data was analyzed using paired t-test. Results The mean age of presentation of EOAD and LOAD was 63.10 years and 84.28 years, respectively, and the difference between the two was found to be statistically significant. The LOAD group had significantly higher symptom severity for delusions, agitation, anxiety, disinhibition, and nighttime behavioral disturbances (NBD) than the EOAD group (p ≤.0001). Conclusion The behavioral and psychological symptoms are significantly severe in late onset subtype compared to the early onset subtype of Alzheimer’s disease in the Kashmiri (Indian) population.  PMID:27433404

An investigation into the effects of antenatal stressors on the postpartum neuroimmune profile and depressive-like behaviors

PubMed Central

Posillico, Caitlin K.; Schwarz, Jaclyn M.

2015-01-01

Postpartum depression is a specific type of depression that affects approximately 10-15% of mothers (Wisner et al., 2013). While many have attributed the etiology of postpartum depression to the dramatic change in hormone levels that occurs immediately postpartum, the exact causes are not well-understood. It is well-known; however, that pregnancy induces a number of dramatic changes in the peripheral immune system that foster the development of the growing fetus. It is also well-known that changes in immune function, specifically within the brain, have been linked to several neuropsychiatric disorders including depression. Thus, we sought to determine whether pregnancy induces significant neuroimmune changes postpartum and whether stress or immune activation during pregnancy induce a unique neuroimmune profile that may be associated with depressive-like behaviors postpartum. We used late-gestation sub-chronic stress and late-gestation acute immune activation to examine the postpartum expression of depressive-like behaviors, microglial activation markers, and inflammatory cytokines within the medial prefrontal cortex (mPFC) and the hippocampus (HP). The expression of many immune molecules was significantly altered in the brain postpartum, and postpartum females also showed significant anhedonia, both independently of stress. Following late-gestation immune activation, we found a unique set of changes in neuroimmune gene expression immediately postpartum. Thus, our data indicate that even in the absence of additional stressors, postpartum females exhibit significant changes in the expression of cytokines within the brain that are associated with depressive-like behavior. Additionally, different forms of antenatal stress produce varying profiles of postpartum neuroimmune gene expression and associated depressive-like behaviors. PMID:26589802

Temperament and behavior in toddlers born preterm with related clinical problems.

PubMed

Cassiano, Rafaela Guilherme Monte; Gaspardo, Claudia Maria; Faciroli, Ricardo Augusto de Deus; Martinez, Francisco Eulógio; Linhares, Maria Beatriz Martins

2017-09-01

The aim of this study was to compare temperament and behavior profiles among groups of preterm toddlers differentiated by level of prematurity and the presence of bronchopulmonary dysplasia (BPD) or retinopathy of prematurity (ROP), controlling for neonatal clinical conditions and chronological age. The sample comprised 100 preterm toddlers segregated according to level of prematurity (75 very preterm and 25 moderate/late preterm) and presence of BPD (n=36) and ROP (n=63). Temperament was assessed by the Early Childhood Behavior Questionnaire and behavior by the Child Behavior Checklist. The MANOVA was performed with a post-hoc univariate test. The level of prematurity and the presence of BPD and ROP did not affect temperament and behavioral problems in toddlers born preterm. However, the covariates age and length of stay in NICU (Neonatal Intensive Care Unit) affected temperament and behavioral problems, respectively. The older toddlers showed higher inhibitory control and lower activity levels than younger toddlers (range of 18-36months-old). Additionally, toddlers who stayed in the NICU longer showed more pervasive development and emotionally reactive problems than toddlers who stayed in NICU for less time. The level of prematurity and the presence of bronchopulmonary dysplasia and retinopathy of prematurity did not affect temperament and behavioral problems in toddlers born preterm. However, a longer stay in the NICU increased the risk for behavioral problems, and age enhanced the regulation of temperament at toddlerhood. Copyright © 2017 Elsevier B.V. All rights reserved.

Grassland songbirds in a dynamic management landscape: Behavioral responses and management strategies

USGS Publications Warehouse

Perlut, N.G.; Strong, A.M.; Donovan, T.M.; Buckley, N.J.

2006-01-01

In recent decades, earlier and more frequent harvests of agricultural grasslands have been implicated as a major cause of population declines in grassland songbirds. From 2002 to 2005, in the Champlain Valley of Vermont and New York, USA, we studied the reproductive success of Savannah Sparrows (Passerculus sandwichensis) and Bobolinks (Dolichonyx oryzivorus) on four grassland treatments: (1) early-hayed fields cut before 11 June and again in early- to mid-July; (2) middle-hayed fields cut once between 21 June and 10 July; (3) late-hayed fields cut after 1 August; and (4) rotationally grazed pastures. Both the number of fledglings per female per year and nest success (logistic-exposure method) varied among treatments and between species. Although birds initiated nests earlier on early-hayed fields compared to others, haying caused 99% of active Savannah Sparrow and 100% of active Bobolink nests to fail. Both the initial cutting date and time between cuttings influenced renesting behavior. After haying, Savannah Sparrows generally remained on early-hayed fields and immediately renested (clutch completion 15.6 ?? 1.28 days post-haying; all values are reported as mean ?? SE), while Bobolinks abandoned the fields for at least two weeks (mean clutch completion 33 ?? 0.82 days post-haying). While female Savannah Sparrows fledged more offspring per year (1.28 ?? 0.16) than female Bobolinks (0.05 ?? 0.05), reproductive success on early-hayed fields was low. The number of fledglings per female per year was greater on middle-hayed fields (Savannah Sparrows, 3.47 ?? 0.42; Bobolinks, 2.22 ?? 0.26), and late-hayed fields (Savannah Sparrows, 3.29 ?? 0.30; Bobolinks, 2.79 ?? 0.18). Reproductive success was moderate on rotationally grazed pastures, where female Savannah Sparrows and female Bobolinks produced 2.32 ?? 0.25 and 1.79 ?? 0.33 fledgling per year, respectively. We simultaneously conducted cutting surveys throughout the Champlain Valley and found that 3-8% of hayfield habitat was cut by 1-4 June, 25-40% by 12-16 June, and 32-60% by 28 June-2 July. Thus, the majority of grassland habitat was cut during the breeding season; however, late-hayed fields served as high-quality reserves for late-nesting female Bobolinks that were displaced from previously hayed fields. For fields first cut in May, a 65-day interval between cuts could provide enough time for both species to successfully fledge young. ?? 2006 by the Ecological Society of America.

Viability costs of reproduction and behavioral compensation in western mosquitofish (Gambusia affinis).

PubMed

Laidlaw, Clinton T; Condon, Jacob M; Belk, Mark C

2014-01-01

The cost of reproduction hypothesis suggests that current reproduction has inherent tradeoffs with future reproduction. These tradeoffs can be both in the form of energy allocated to current offspring as opposed to somatic maintenance and future reproduction (allocation costs), or as an increase in mortality as a result of morphological or physiological changes related to reproduction (viability costs). Individuals may be able to decrease viability costs by altering behavior. Female western mosquitofish, Gambusia affinis experience a reduction in swimming ability as a consequence of pregnancy. We test for a viability cost of reproduction, and for behavioral compensation in pregnant female G. affinis by measuring survival of females in early and later stages of pregnancy when exposed to predation. Late-stage pregnant females experience a 70% greater probability of mortality compared to early-stage pregnant females. The presence of a refuge roughly doubled the odds of survival of both early and late-stage pregnant females. However, there was no interaction between refuge availability and stage of pregnancy. These data do not provide evidence for behavioral compensation by female G. affinis for elevated viability costs incurred during later stages of pregnancy. Behavioral compensation may be constrained by other aspects of the cost of reproduction.

Mothers’ and Fathers’ Autonomy-Relevant Parenting: Longitudinal Links with Adolescents’ Externalizing and Internalizing Behavior

PubMed Central

Lansford, Jennifer E.; Laird, Robert D.; Pettit, Gregory S.; Bates, John E.; Dodge, Kenneth A.

2014-01-01

The goal of this study was to advance the understanding of separate and joint effects of mothers’ and fathers’ autonomy-relevant parenting during early and middle adolescence. In a sample of 518 families, adolescents (49% female; 83% European American, 16% African American, 1% other ethnic groups) reported on their mothers’ and fathers’ psychological control and knowledge about adolescents’ whereabouts, friends, and activities at ages 13 and 16. Mothers and adolescents reported on adolescents’ externalizing and internalizing behaviors at ages 12, 14, 15, and 17. Adolescents perceived their mothers as using more psychological control and having more knowledge than their fathers, but there was moderate concordance between adolescents’ perceptions of their mothers and fathers. More parental psychological control predicted increases in boys’ and girls’ internalizing problems and girls’ externalizing problems. More parental knowledge predicted decreases in boys’ externalizing and internalizing problems. The perceived levels of behavior of mothers and fathers did not interact with one another in predicting adolescent adjustment. The results generalize across early and late adolescence and across mothers’ and adolescents’ reports of behavior problems. Autonomy-relevant mothering and fathering predict changes in behavior problems during early and late adolescence, but only autonomy-relevant fathering accounts for unique variance in adolescent behavior problems. PMID:24337705

Mothers' and fathers' autonomy-relevant parenting: longitudinal links with adolescents' externalizing and internalizing behavior.

PubMed

Lansford, Jennifer E; Laird, Robert D; Pettit, Gregory S; Bates, John E; Dodge, Kenneth A

2014-11-01

The goal of this study was to advance the understanding of separate and joint effects of mothers' and fathers' autonomy-relevant parenting during early and middle adolescence. In a sample of 518 families, adolescents (49 % female; 83 % European American, 16 % African American, 1 % other ethnic groups) reported on their mothers' and fathers' psychological control and knowledge about adolescents' whereabouts, friends, and activities at ages 13 and 16. Mothers and adolescents reported on adolescents' externalizing and internalizing behaviors at ages 12, 14, 15, and 17. Adolescents perceived their mothers as using more psychological control and having more knowledge than their fathers, but there was moderate concordance between adolescents' perceptions of their mothers and fathers. More parental psychological control predicted increases in boys' and girls' internalizing problems and girls' externalizing problems. More parental knowledge predicted decreases in boys' externalizing and internalizing problems. The perceived levels of behavior of mothers and fathers did not interact with one another in predicting adolescent adjustment. The results generalize across early and late adolescence and across mothers' and adolescents' reports of behavior problems. Autonomy-relevant mothering and fathering predict changes in behavior problems during early and late adolescence, but only autonomy-relevant fathering accounts for unique variance in adolescent behavior problems.

Cognitive impulsivity and the development of delinquency from late childhood to early adulthood: Moderating effects of parenting behavior and peer relationships.

PubMed

Menting, Barbara; Van Lier, Pol A C; Koot, Hans M; Pardini, Dustin; Loeber, Rolf

2016-02-01

Cognitive impulsivity may increase children's risk of developing delinquent behavior. However, the influence of cognitive impulsivity may depend on social environmental risk factors. This study examined the moderating effect of late childhood parenting behaviors and peer relations on the influence of children's cognitive impulsivity on delinquency development across adolescence and early adulthood, while taking possible interactions with intelligence also into account. Delinquent behavior of 412 boys from the Pittsburgh Youth Study was measured annually from ages 13 to 29 years with official arrest records. Cognitive impulsivity (neurocognitive test scores) and intelligence were assessed at age 12-13. Parenting behaviors (persistence of discipline, positive reinforcement, and parental knowledge), peer delinquency, and peer conventional activities were assessed between ages 10 and 13 years. Results showed that, while controlling for intelligence, the influence of youths' cognitive impulsivity on delinquency depended on their parents' behaviors. An interaction was found among cognitive impulsivity, intelligence, and peer delinquency, but instead of cognitive impulsivity, the effect of intelligence on delinquency was particularly moderated. Overall, findings suggest that when there was moderation, high cognitive impulsivity and low intelligence were associated with an increased probability for engaging in delinquency predominantly among boys in a good social environment, but not in a poor social environment.

Early and late changes in the distal forelimb representation of the supplementary motor area after injury to frontal motor areas in the squirrel monkey.

PubMed

Eisner-Janowicz, Ines; Barbay, Scott; Hoover, Erica; Stowe, Ann M; Frost, Shawn B; Plautz, Erik J; Nudo, Randolph J

2008-09-01

Neuroimaging studies in stroke survivors have suggested that adaptive plasticity occurs following stroke. However, the complex temporal dynamics of neural reorganization after injury make the interpretation of functional imaging studies equivocal. In the present study in adult squirrel monkeys, intracortical microstimulation (ICMS) techniques were used to monitor changes in representational maps of the distal forelimb in the supplementary motor area (SMA) after a unilateral ischemic infarct of primary motor (M1) and premotor distal forelimb representations (DFLs). In each animal, ICMS maps were derived at early (3 wk) and late (13 wk) postinfarct stages. Lesions resulted in severe deficits in motor abilities on a reach and retrieval task. Limited behavioral recovery occurred and plateaued at 3 wk postinfarct. At both early and late postinfarct stages, distal forelimb movements could still be evoked by ICMS in SMA at low current levels. However, the size of the SMA DFL changed after the infarct. In particular, wrist-forearm representations enlarged significantly between early and late stages, attaining a size substantially larger than the preinfarct area. At the late postinfarct stage, the expansion in the SMA DFL area was directly proportional to the absolute size of the lesion. The motor performance scores were positively correlated to the absolute size of the SMA DFL at the late postinfarct stage. Together, these data suggest that, at least in squirrel monkeys, descending output from M1 and dorsal and ventral premotor cortices is not necessary for SMA representations to be maintained and that SMA motor output maps undergo delayed increases in representational area after damage to other motor areas. Finally, the role of SMA in recovery of function after such lesions remains unclear because behavioral recovery appears to precede neurophysiological map changes.

Isotopic evidence for Last Glacial climatic impacts on Neanderthal gazelle hunting territories at Amud Cave, Israel.

PubMed

Hartman, Gideon; Hovers, Erella; Hublin, Jean-Jacques; Richards, Michael

2015-07-01

The Middle Paleolithic site of Amud Cave, Israel, was occupied by Neanderthals at two different time periods, evidenced by two chronologically and stratigraphically distinct depositional sub-units (B4 and B2/B1) during MIS 4 and MIS 3, respectively. The composition of both hunted large fauna and naturally-deposited micromammalian taxa is stable at the site over time, despite a ∼ 10 ky gap between the two occupation phases. However, while gazelle is the most ubiquitous hunted species throughout the occupation, isotopic analysis showed that there is a marked change in Neanderthal hunting ranges between the early (B4) and late (B2/B1) phases. Hunting ranges were reconstructed by comparing oxygen, carbon, and strontium isotopes from gazelle tooth enamel with modern isotope data from the Amud Cave region. This region is characterized by extensive topographic, lithological, and pedological heterogeneity. During the early occupation phase negative oxygen isotope values, low radiogenic (87)Sr/(86)Sr ratios, and low Sr concentrations reveal restricted gazelle hunting in the high elevations west of Amud Cave. In the late occupation phase, hunting ranges became more diverse, but concentrate at low elevations closer to the site. Climatic proxies indicate that conditions were drier in the early occupation phase, which may have pushed gazelle populations into higher, more productive foraging areas. This study showed that Neanderthals adjusted their hunting territories considerably in relation to varying environmental conditions over the course of occupation in Amud Cave. It highlights the utility of multiple isotope analysis in enhancing the resolution of behavioral interpretations based on faunal remains and in reconstructing past hunting behaviors of Paleolithic hominins. Copyright © 2015 Elsevier Ltd. All rights reserved.

Neural Correlates of Response Inhibition and Cigarette Smoking in Late Adolescence

PubMed Central

Galván, Adriana; Poldrack, Russell A; Baker, Christine M; McGlennen, Kristine M; London, Edythe D

2011-01-01

Smoking is usually initiated in adolescence, and is the leading preventable cause of death in the United States. Little is known, however, about the links between smoking and neurobiological function in adolescent smokers. This study aimed to probe prefrontal cortical function in late adolescent smokers, using a response inhibition task, and to assess possible relationships between inhibition-related brain activity, clinical features of smoking behavior, and exposure to cigarette smoking. Participants in this study were otherwise healthy late adolescent smokers (15–21 years of age; n=25), who reported daily smoking for at least the 6 months before testing, and age- and education-matched nonsmokers (16–21 years of age; n=25), who each reported smoking fewer than five cigarettes in their lifetimes. The subjects performed the Stop-signal Task, while undergoing functional magnetic resonance imaging. There were no significant group differences in prefrontal cortical activity during response inhibition, but the Heaviness of Smoking Index, a measure of smoking behavior and dependence, was negatively related to neural function in cortical regions of the smokers. These findings suggest that smoking can modulate prefrontal cortical function. Given the late development of the prefrontal cortex, which continues through adolescence, it is possible that smoking may influence the trajectory of brain development during this critical developmental period. PMID:21270772

Does competence mediate the associations between puberty and internalizing or externalizing problems in adolescent girls?

PubMed

Negriff, Sonya; Hillman, Jennifer B; Dorn, Lorah D

2011-10-01

To examine separate mediational models linking (a) menarcheal status or (b) pubertal timing to internalizing and externalizing problems through competence. This study involved cross-sectional analyses of 262 adolescent girls (age: 11-17 years; mean = 14.93, standard deviation = 2.17) enrolled in a longitudinal study examining the association of psychological functioning and smoking with reproductive and bone health. Measures of menarcheal status (pre/post), pubertal timing (early, on-time, or late), internalizing and externalizing behavior, and perceived competence (parent and adolescent report) were obtained. Structural equation modeling was used for analyses. Perceived competence was found to fully mediate the association between menarcheal status and parent report of internalizing and externalizing problems. For adolescent report, there was a full mediation effect for internalizing problems but a partial mediation effect for externalizing problems. Being menarcheal was related to lower competence, which was in turn related to higher internalizing and externalizing problems. Models including pubertal timing were not significant. Perceived competence is important in understanding the associations between menarcheal status and internalizing and externalizing problems. Interventions targeting competence, particularly in postmenarcheal girls, may reduce or prevent problem behaviors. Copyright © 2011 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

Teacher-Child Relationship Quality and Children's Peer Victimization and Aggressive Behavior in Late Childhood

ERIC Educational Resources Information Center

Troop-Gordon, Wendy; Kopp, Jessica

2011-01-01

This investigation examines the extent to which characteristics of the teacher-child relationship (closeness, dependency, and conflict) are predictive of changes in children's peer victimization and aggressive behavior over the course of a school year. Relational and physical forms of victimization and aggression were studied, and changes in peer…

Translating Research for Professional Development and Effective Clinical Practice with Older Adults

ERIC Educational Resources Information Center

Steffen, Ann M.

2012-01-01

This paper offers a commentary on the articles in the special series on cognitive behavior therapy with older adults (Carmin, 2012-this issue), noting the commonalities found across discussions of diagnostic interviewing and cognitive-behavioral assessment and treatment for late-life insomnia, depression and suicide risk, PTSD, and OCD. These case…

Social and Physical Aggression Trajectories from Childhood through Late Adolescence: Predictors of Psychosocial Maladjustment at Age 18

ERIC Educational Resources Information Center

Ehrenreich, Samuel E.; Beron, Kurt J.; Underwood, Marion K.

2016-01-01

This research examined whether following social and physical aggression trajectories across Grades 3-12 predicted psychological maladjustment. Teachers rated participants' (n = 287, 138 boys) aggressive behavior at the end of each school year. Following the 12th grade, psychosocial outcomes were measured: rule-breaking behaviors, internalizing…

Body Mass Index Self-Perception and Weight Management Behaviors during Late Adolescence

ERIC Educational Resources Information Center

Yang, Kyeongra; Turk, Melanie T.; Allison, Virginia L.; James, Khara A.; Chasens, Eileen

2014-01-01

Background: This study examined the relationship between actual body weight and self-perceived weight, and how perception of one's weight affects weight management behaviors among US adolescents. Methods: Adolescents ages 16-19 years with objectively-measured weight and height and self-reported perception of weight, weight-loss efforts, and…

Adolescence as a period of vulnerability and intervention in schizophrenia: Insights from the MAM model.

PubMed

Gomes, Felipe V; Rincón-Cortés, Millie; Grace, Anthony A

2016-11-01

Adolescence is a time of extensive neuroanatomical, functional and chemical reorganization of the brain, which parallels substantial maturational changes in behavior and cognition. Environmental factors that impinge on the timing of these developmental factors, including stress and drug exposure, increase the risk for psychiatric disorders. Indeed, antecedents to affective and psychotic disorders, which have clinical and pathophysiological overlap, are commonly associated with risk factors during adolescence that predispose to these disorders. In the context of schizophrenia, psychosis typically begins in late adolescence/early adulthood, which has been replicated by animal models. Rats exposed during gestational day (GD) 17 to the mitotoxin methylazoxymethanol acetate (MAM) exhibit behavioral, pharmacological, and anatomical characteristics consistent with an animal model of schizophrenia. Here we provide an overview of adolescent changes within the dopamine system and the PFC and review recent findings regarding the effects of stress and cannabis exposure during the peripubertal period as risk factors for the emergence of schizophrenia-like deficits. Finally, we discuss peripubertal interventions appearing to circumvent the emergence of adult schizophrenia-like deficits. Copyright © 2016 Elsevier Ltd. All rights reserved.

On the universality of Marangoni-driven spreading

NASA Astrophysics Data System (ADS)

Visser, Claas; van Capelleveen, Bram; Koldeweij, Robin; Lohse, Detlef

2017-11-01

When two liquids of different surface tensions come into contact, the liquid with lower surface tension spreads over the other. Here we measure the dynamics of this Marangoni-driven spreading in the drop-drop geometry, revealing universal behavior with respect to the control parameters as well as other geometries (such as spreading over a flat interface). The distance L over which the low-surface-tension liquid has covered the high-surface-tension droplet is measured as a function of time t, surface tension difference between the liquids Δσ , and viscosity η, revealing power-law behavior L(t) tα . The exponent α is discussed for the early and late spreading regimes. Spreading inhibition is observed at high viscosity, for which the threshold is discussed. Finally, we show that our results collapse onto a single curve of dimensionless L(t) as a function of dimensionless time, which also captures previous results for different geometries, surface tension modifiers, and miscibility. As this curve spans 7 orders of magnitude, Marangoni-induced spreading can be considered a universal phenomenon for many practically encountered liquid-liquid systems.

Prosocial development in late adolescence: a longitudinal study.

PubMed

Eisenberg, N; Carlo, G; Murphy, B; Van Court, P

1995-08-01

Change in prosocial moral reasoning over 15 years, gender differences in prosocial reasoning, and the interrelations of moral reasoning, prosocial behavior, and empathy-related emotional responses were examined with longitudinal data from 17-18- and 19-20-year-olds and data from adolescents interviewed for the first time. Hedonistic reasoning declined in use until adolescence, and then increased somewhat in early adulthood. Needs-oriented and stereotypic reasoning increased until mid-childhood or early adolescence and then declined in use. Direct reciprocity and approval reasoning, which appeared to be on the decline in mid-adolescence in previous follow-ups, showed no decline into early adulthood. Several modes of higher-level reasoning increased in use across adolescence and early adulthood. Females' overall reasoning was higher than males'. Scores on interview and objective measures of prosocial moral reasoning were positively correlated. Consistent with expectations, there was some evidence of relations among prosocial reasoning, prosocial behavior, sympathy, and perspective taking.

Sensory Augmentation for the Blind

PubMed Central

Kärcher, Silke M.; Fenzlaff, Sandra; Hartmann, Daniela; Nagel, Saskia K.; König, Peter

2012-01-01

Common navigational aids used by blind travelers during large-scale navigation divert attention away from important cues of the immediate environment (i.e., approaching vehicles). Sensory augmentation devices, relying on principles similar to those at work in sensory substitution, can potentially bypass the bottleneck of attention through sub-cognitive implementation of a set of rules coupling motor actions with sensory stimulation. We provide a late blind subject with a vibrotactile belt that continually signals the direction of magnetic north. The subject completed a set of behavioral tests before and after an extended training period. The tests were complemented by questionnaires and interviews. This newly supplied information improved performance on different time scales. In a pointing task we demonstrate an instant improvement of performance based on the signal provided by the device. Furthermore, the signal was helpful in relevant daily tasks, often complicated for the blind, such as keeping a direction over longer distances or taking shortcuts in familiar environments. A homing task with an additional attentional load demonstrated a significant improvement after training. The subject found the directional information highly expedient for the adjustment of his inner maps of familiar environments and describes an increase in his feeling of security when exploring unfamiliar environments with the belt. The results give evidence for a firm integration of the newly supplied signals into the behavior of this late blind subject with better navigational performance and more courageous behavior in unfamiliar environments. Most importantly, the complementary information provided by the belt lead to a positive emotional impact with enhanced feeling of security. The present experimental approach demonstrates the positive potential of sensory augmentation devices for the help of handicapped people. PMID:22403535

The protective effects of good parenting on adolescents.

PubMed

DeVore, Elise R; Ginsburg, Kenneth R

2005-08-01

To explore recent developments in the literature regarding parenting practices and adolescent development, with a focus on parenting style, parental monitoring, communication, and supervision. There have been significant recent advances in the study of the relationship between parenting and adolescent development. Several recent intervention studies with a parenting component demonstrated immediate and long-term protective effects on adolescent risk behavior. Parent-child connectedness and authoritative parenting style are protective for teens. Parental monitoring has a protective effect on many adolescent risk behaviors in both middle-class populations and poor urban environments and has been shown both to moderate the effect of peer influence and to persist into late adolescence. Whereas unsupervised time, exposure to sexual possibility situations, and out-of-home care increase sexual behavior, improved parent-child communication reduces sexual risk behaviors. Recent scholarship demonstrates the significant, enduring, and protective influence of positive parenting practices on adolescent development. In particular, parental monitoring, open parent-child communication, supervision, and high quality of the parent-child relationship deter involvement in high-risk behavior. Authoritative parenting generally leads to the best outcomes for teens. Clinicians should find opportunities to discuss evidence-based parenting practices with families. Future research should focus on the development and long-term evaluation of effective parenting interventions.

Tailored mental health care after nursing home admission: improving transfers of people with dementia with behavioral problems. An explorative study.

PubMed

Van Mierlo, L D; Bootsma-Van der Wiel, A; Meiland, F J M; Van Hout, H P J; Stek, M L; Dröes, R M

2015-01-01

In the Netherlands, many community-dwelling people with dementia and behavioral disturbances and their family caregivers receive mental health care from a community psychiatric nurse (CPN). To promote continuity of care for these persons after moving to a nursing home, a transfer intervention was developed. The aim of this explorative study was to evaluate this intervention and its implementation. A qualitative explorative study design was used. CPNs visited professional nursing home carers, people with dementia and family caregivers six weeks after moving, advised on how to manage behavioral problems of their former clients and provided support to family caregivers. Twenty-two interviews were conducted with participants exposed to the intervention (5 CPNs, 5 family and 12 nursing home carers) and with 11 stakeholders (i.e., nursing home and mental health care managers, professional caregivers) to identify facilitators and barriers to the implementation. Data were collected in 2012 and 2013. The follow-up visit at six weeks met the need for background information of new admitted patients and helped family caregivers close off the period prior to the move. It did not meet the original purpose of providing nursing home staff with advice about problem behaviors on time: six weeks after the move was experienced as too late. The transfer intervention increased the awareness of nursing home staff about personal and behavioral characteristics of residents with dementia and supported caregivers in coping with the new situation. The timing of the intervention could be improved by scheduling it immediately after the move.

Vocal activities reflect the temporal distribution of bottlenose dolphin social and non-social activity in a zoological park.

PubMed

Lima, Alice; Lemasson, Alban; Boye, Martin; Hausberger, Martine

2017-12-01

Under natural conditions bottlenose dolphins (Tursiops truncatus) spend their time mostly feeding and then travelling, socializing, or resting. These activities are not randomly distributed, with feeding being higher in early morning and late afternoon. Social activities and vocal behavior seem to be very important in dolphin daily activity. This study aimed to describe the activity time-budget and its relation to vocal behavior for dolphins in a zoological park. We recorded behaviors and vocalizations of six dolphins over 2 months. All subjects performed more non-agonistic social interactions and play in the morning than in the afternoon. The different categories of vocalizations were distributed non-randomly throughout the day, with more chirps in the afternoon, when the animals were "less social." The most striking result was the strong correlation between activities and the categories of vocalizations produced. The results confirm the association between burst pulses and whistles with social activities, but also reveal that both are also associated with solitary play. More chirps were produced when dolphins were engaged in socio-sexual behaviors, emphasizing the need for further questioning about the function of this vocal category. This study reveals that: (i) in a group kept in zoological management, social activities are mostly present in the morning; and (ii) the acoustic signals produced by dolphins may give a reliable representation of their current activities. While more studies on the context of signal production are needed, our findings provide a useful tool for understanding free ranging dolphin behavior when they are not visible. © 2017 Wiley Periodicals, Inc.

Combined eating behaviors and overweight: Eating quickly, late evening meals, and skipping breakfast.

PubMed

Lee, Jung Su; Mishra, Gita; Hayashi, Kunihiko; Watanabe, Etsuko; Mori, Katsumi; Kawakubo, Kiyoshi

2016-04-01

Various eating behaviors have been linked with body weight management. However, combined effects of major eating behaviors are not fully understood. This study aimed to clarify the association of the combination of eating quickly (EQ), late evening meals (LEM), and skipping breakfast (SB) with being overweight. A cross-sectional study with standardized questions for EQ, LEM, and SB was conducted. Stratified random sampling of 5% of residents aged 20 to 80years was surveyed in a city in northeast Japan in 2011, and 4249 (84.9%) residents were analyzed. Association of combinations of eating behaviors on being overweight (BMI (kg/m(2)≥25.0)) was estimated by using logistic analysis, and odds ratio (OR) and 95% confidential interval were calculated after adjustment for potential covariates. LEM, SB, or a combination of LEM and SB was not significantly associated with being overweight. However, the combination of EQ or only EQ was significantly associated with being overweight. As the number of eating behavior practices increased, there was a linear increase in OR for being overweight. The OR of all three combined eating behaviors was higher than that of any combined two behaviors or of each behavior. This study result supports the evidence that EQ increases the risk of being overweight whether by itself or in combinations with LEM and/or SB. However, only LEM or only SB did not increase the risk of being overweight. Copyright © 2016 Elsevier Ltd. All rights reserved.

Revealing Behavioral Learning Deficit Phenotypes Subsequent to In Utero Exposure to Benzo(a)pyrene

PubMed Central

McCallister, Monique M.; Li, Zhu; Zhang, Tongwen; Ramesh, Aramandla; Clark, Ryan S.; Maguire, Mark; Hutsell, Blake; Newland, M. Christopher; Hood, Darryl B.

2016-01-01

To characterize behavioral deficits in pre-adolescent offspring exposed in utero to Benzo(a)pyrene [B(a)P], timed-pregnant Long Evans Hooded rats were treated with B(a)P (150, 300, 600, and 1200 µg/kg BW) or peanut oil (vehicle) on E14, 15, 16, and 17. Following birth, during the pre-weaning period, B(a)P metabolites were examined in plasma and whole brain or cerebral cortex from exposed and control offspring. Tissue concentrations of B(a)P metabolites were (1) dose-dependent and (2) followed a time-dependence for elimination with ∼60% reduction by PND5 in the 1200 µg/kg BW experimental group. Spatial discrimination-reversal learning was utilized to evaluate potential behavioral neurotoxicity in P40–P60 offspring. Late-adolescent offspring exposed in utero to 600 and 1200 µg/kg BW were indistinguishable from their control counterparts for ability to acquire an original discrimination (OD) and reach criterion. However, a dose-dependent effect of in utero B(a)P-exposure was evident upon a discrimination reversal as exposed offspring perseverated on the previously correct response. This newly characterized behavioral deficit phenotype for the first reversal was not apparent in either the (1) OD or (2) subsequent reversal sessions relative to the respective control offspring. Furthermore, the expression of activity related-cytoskeletal-associated protein (Arc), an experience-dependent cortical protein marker known to be up-regulated in response to acquisition of a novel behavior, was greater in B(a)P-exposed offspring included in the spatial discrimination cohort versus home cage controls. Collectively, these findings support the hypothesis that in utero exposure to B(a)P during critical windows of development representing peak periods of neurogenesis results in behavioral deficits in later life. PMID:26420751

Impact of Submesoscale Processes on Dynamics of Phytoplankton Filaments

DTIC Science & Technology

2015-02-12

submesoscale processes on the formation of chlorophyll a filaments during late springearlier summer, and late summer time frames. We show that during...the late summer time frame, ASC leads to the development of filaments with high values of chlorophyll a concentration along the edge of the cold jet...in contrast to the earlier summer time, when the ASC mixes phytoplankton much deeper to the area below of the euphotic depth, and chlorophyll a

A note on tilted Bianchi type VIh models: the type III bifurcation

NASA Astrophysics Data System (ADS)

Coley, A. A.; Hervik, S.

2008-10-01

In this note we complete the analysis of Hervik, van den Hoogen, Lim and Coley (2007 Class. Quantum Grav. 24 3859) of the late-time behaviour of tilted perfect fluid Bianchi type III models. We consider models with dust, and perfect fluids stiffer than dust, and eludicate the late-time behaviour by studying the centre manifold which dominates the behaviour of the model at late times. In the dust case, this centre manifold is three-dimensional and can be considered a double bifurcation as the two parameters (h and γ) of the type VIh model are varied. We therefore complete the analysis of the late-time behaviour of tilted ever-expanding Bianchi models of types I VIII.

Neuropsychological deficits in preschool as predictors of ADHD symptoms and academic achievement in late adolescence

PubMed Central

Sjöwall, Douglas; Bohlin, Gunilla; Rydell, Ann-Margret; Thorell, Lisa B

2017-01-01

High levels of ADHD symptoms are related to severe negative outcomes, which underscore the importance of identifying early markers of these behavior problems. The main aim of the present study was therefore to investigate whether neuropsychological deficits in preschool are related to later ADHD symptoms and academic achievement, over and above the influence of early ADHD symptom levels. The present study is unique because it includes a broader range of predictors compared to previous studies and the participants are followed over time for as long as 13 years (i.e., ages 5–18 years). Preschool data included measures of executive functioning and reaction time variability as well as emotional reactivity and emotion regulation of both positive and negative emotions. When controlling for early ADHD symptom levels, working memory, reaction time variability, and regulation of happiness/exuberance were significantly related to inattention whereas regulation of happiness/exuberance and anger reactivity were significantly related to hyperactivity/impulsivity. Furthermore, working memory and reaction time variability in preschool were significantly related to academic achievement in late adolescence beyond the influence of early ADHD symptoms. These findings could suggest that it is possible to screen for early neuropsychological deficits and thereby identify children who are at risk of negative outcomes. Furthermore, our results suggest that interventions need to look beyond executive functioning deficits in ADHD and also target the role of emotional functioning and reaction time variability. The importance of including both the positive and negative aspects of emotional functioning and distinguishing between emotion regulation and emotional reactivity was also demonstrated. PMID:26212755

How Reducing was the Late Devonian Ocean? The Role of Extensive Expansion of Anoxia in Marine Biogeochemical Cycles of Redox Sensitive Metals.

NASA Astrophysics Data System (ADS)

Sahoo, S. K.; Jin, H.

2017-12-01

The evolution of Earth's biogeochemical cycles is intimately linked to the oxygenation of the oceans and atmosphere. The Late Devonian is no exception as its characterized with mass extinction and severe euxinia. Here we use concentrations of Molybdenum (Mo), Vanadium (V), Uranium (U) and Chromium (Cr) in organic rich black shales from the Lower Bakken Formation of the Williston Basin, to explore the relationship between extensive anoxia vs. euxinia and it's relation with massive release of oxygen in the ocean atmosphere system. XRF data from 4 core across the basin shows that modern ocean style Mo, U and Cr enrichments are observed throughout the Lower Bakken Formation, yet V is not enriched until later part of the formation. Given the coupling between redox-sensitive-trace element cycles and ocean redox, various models for Late Devonian ocean chemistry imply different effects on the biogeochemical cycling of major and trace nutrients. Here, we examine the differing redox behavior of molybdenum and vanadium under an extreme anoxia and relatively low extent of euxinia. The model suggests that Late Devonian was perhaps extensively anoxic- 40-50% compared to modern seafloor area, and a very little euxinia. Mo enrichments extend up to 500 p.p.m. throughout the section, representative of a modern reducing ocean. However, coeval low V enrichments only support towards anoxia, where anoxia is a source of V, and a sink for Mo. Our model suggests that the oceanic V reservoir is extremely sensitive to perturbations in the extent of anoxic condition, particularly during post glacial times.

Cyclic impacts on heel strike: a possible biomechanical factor in the etiology of degenerative disease of the human locomotor system.

PubMed

Folman, Y; Wosk, J; Voloshin, A; Liberty, S

1986-01-01

The cyclic impacts induced by heel strike when walking were studied using both a high-resonance-frequency force plate and a low-mass skin-mounted accelerometer. The data were computer analyzed. The results showed that during normal human walking, the locomotor system is subjected to repetitive impact loads at heel strike, lasting about 5 ms and consisting of frequency spectra up to and above 100 Hz. The natural shock-absorbing structures in the musculoskeletal system have viscoelastic time-dependent mechanical behavior, which is relatively ineffective in withstanding sudden impulsive loads. Degenerative joint diseases may thus be seen as a late clinical result of fatigue failure of the natural shock absorbers, submitted to deleterious impacts over a period of time.

Binary black holes' effects on electromagnetic fields.

PubMed

Palenzuela, Carlos; Anderson, Matthew; Lehner, Luis; Liebling, Steven L; Neilsen, David

2009-08-21

In addition to producing gravitational waves, the dynamics of a binary black hole system could induce emission of electromagnetic radiation by affecting the behavior of plasmas and electromagnetic fields in their vicinity. We here study how the electromagnetic fields are affected by a pair of orbiting black holes through the merger. In particular, we show how the binary's dynamics induce a variability in possible electromagnetically induced emissions as well as a possible enhancement of electromagnetic fields during the late-merge and merger epochs. These time dependent features will likely leave their imprint in processes generating detectable emissions and can be exploited in the detection of electromagnetic counterparts of gravitational waves.

The Bermuda Triangle of cocaine-induced neuroadaptations.

PubMed

Wolf, Marina E

2010-09-01

Activation of medium spiny neurons (MSNs) of the nucleus accumbens is critical for goal-directed behaviors including cocaine seeking. Studies in cocaine-experienced rodents have revealed three major categories of neuroadaptations that influence the ability of glutamate inputs to activate MSNs: changes in synaptic AMPA receptor levels, changes in extracellular non-synaptic glutamate levels and changes in MSN intrinsic membrane excitability. Most studies have focused on one of these adaptations. This review will consider the possibility that they are causally related and speculate about how time-dependent changes in their interactions may regulate MSN output during early and late withdrawal from repeated cocaine exposure. Copyright 2010 Elsevier Ltd. All rights reserved.

The Bermuda Triangle of Cocaine-Induced Neuroadaptations

PubMed Central

Wolf, Marina E.

2010-01-01

Activation of medium spiny neurons (MSN) of the nucleus accumbens is critical for goal-directed behaviors including cocaine seeking. Studies in cocaine-experienced rodents have revealed three major categories of neuroadaptations that influence the ability of glutamate inputs to activate MSN: changes in synaptic AMPA receptor levels, changes in extracellular non-synaptic glutamate levels, and changes in MSN intrinsic membrane excitability. Most studies have focused on one of these adaptations. Here, we consider the possibility that they are causally related and speculate about how time-dependent changes in their interactions may regulate MSN output during early and late withdrawal from repeated cocaine exposure. PMID:20655604

A Search for a General Phenomenon of Adaptive Mutability

PubMed Central

Galitski, T.; Roth, J. R.

1996-01-01

The most prominent systems for the study of adaptive mutability depend on the specialized activities of genetic elements like bacteriophage Mu and the F plasmid. Searching for general adaptive mutability, we have investigated the behavior of Salmonella typhimurium strains with chromosomal lacZ mutations. We have studied 30 revertible nonsense, missense, frameshift, and insertion alleles. One-third of the mutants produced >=10 late revertant colonies (appearing three to seven days after plating on selective medium). For the prolific mutants, the number of late revertants showed rank correlation with the residual β-galactosidase activity; for the same mutants, revertant number showed no correlation with the nonselective reversion rate (from fluctuation tests). Leaky mutants, which grew slowly on selective medium, produced late revertants whereas tight nongrowing mutants generally did not produce late revertants. However, the number of late revertants was not proportional to residual growth. Using total residual growth and the nonselective reversion rate, the expected number of late revertants was calculated. For several leaky mutants, the observed revertant number exceeded the expected number. We suggest that excess late revertants from these mutants arise from general adaptive mutability available to any chromosomal gene. PMID:8725216

Logarithmic speed-up of relaxation in A -B annihilation with exclusion

NASA Astrophysics Data System (ADS)

Dandekar, Rahul

2018-04-01

We show that the decay of the density of active particles in the reaction A +B →0 in one dimension, with exclusion interaction, results in logarithmic corrections to the expected power law decay, when the starting initial condition (i.c.) is periodic. It is well known that the late-time density of surviving particles goes as t-1 /4 with random initial conditions, and as t-1 /2 with alternating initial conditions (A B A B A B ⋯ ). We show that the decay for periodic i.c.'s made of longer blocks (AnBnAnBn⋯ ) do not show a pure power-law decay when n is even. By means of first-passage Monte Carlo simulations, and a mapping to a q -state coarsening model which can be solved in the independent interval approximation (IIA), we show that the late-time decay of the density of surviving particles goes as t-1 /2[ln(t ) ] -1 for n even, but as t-1 /2 when n is odd. We relate this kinetic symmetry breaking in the Glauber Ising model. We also see a very slow crossover from a t-1 /2[ln(t ) ] -1 regime to eventual t-1 /2 behavior for i.c.'s made of mixtures of odd- and even-length blocks.

Endocrine changes in male stumptailed macaques (Macaca arctoides) as a response to odor stimulation with vaginal secretions.

PubMed

Cerda-Molina, Ana Lilia; Hernández-López, Leonor; Chavira, Roberto; Cárdenas, Mario; Paez-Ponce, Denisse; Cervantes-De la Luz, Harry; Mondragón-Ceballos, Ricardo

2006-01-01

In mammalian species, social chemosignals are important in modulating endocrine reproductive functions. In nonhuman primates, previous studies have described a high frequency of mounting behavior by females in the follicular and periovulatory phases of the menstrual cycle. Stumptailed macaque females do not signal receptivity by means of sexual swellings, as do others macaques, therefore providing a good model in which to study chemical signaling of reproductive status. We exposed anesthetized stumptailed males to vaginal secretions of either late follicular or menses phase or to saline solution to determine the endocrine changes promoting male sexual behavior. In males exposed to follicular secretions, plasma testosterone concentrations were sustained up to 120 min after exposure. Such an effect was not observed in animals exposed to menses or saline odor sources. A luteinizing hormone surge, occurring 30 minutes after exposure to late follicular phase secretion swabs, preceded this sustained testosterone effect. The fact that late follicular scents induce sustained testosterone concentrations provides support to the idea that stumptailed males draw information concerning female reproductive status from the female's vaginal odor.

Humpback whale song and foraging behavior on an antarctic feeding ground.

PubMed

Stimpert, Alison K; Peavey, Lindsey E; Friedlaender, Ari S; Nowacek, Douglas P

2012-01-01

Reports of humpback whale (Megaptera novaeangliae) song chorusing occurring outside the breeding grounds are becoming more common, but song structure and underwater behavior of individual singers on feeding grounds and migration routes remain unknown. Here, ten humpback whales in the Western Antarctic Peninsula were tagged in May 2010 with non-invasive, suction-cup attached tags to study foraging ecology and acoustic behavior. Background song was identified on all ten records, but additionally, acoustic records of two whales showed intense and continuous singing, with a level of organization and structure approaching that of typical breeding ground song. The songs, produced either by the tagged animals or close associates, shared phrase types and theme structure with one another, and some song bouts lasted close to an hour. Dive behavior of tagged animals during the time of sound production showed song occurring during periods of active diving, sometimes to depths greater than 100 m. One tag record also contained song in the presence of feeding lunges identified from the behavioral sensors, indicating that mating displays occur in areas worthy of foraging. These data show behavioral flexibility as the humpbacks manage competing needs to continue to feed and to prepare for the breeding season during late fall. This may also signify an ability to engage in breeding activities outside of the traditional, warm water breeding ground locations.

Humpback Whale Song and Foraging Behavior on an Antarctic Feeding Ground

PubMed Central

Stimpert, Alison K.; Peavey, Lindsey E.; Friedlaender, Ari S.; Nowacek, Douglas P.

2012-01-01

Reports of humpback whale (Megaptera novaeangliae) song chorusing occurring outside the breeding grounds are becoming more common, but song structure and underwater behavior of individual singers on feeding grounds and migration routes remain unknown. Here, ten humpback whales in the Western Antarctic Peninsula were tagged in May 2010 with non-invasive, suction-cup attached tags to study foraging ecology and acoustic behavior. Background song was identified on all ten records, but additionally, acoustic records of two whales showed intense and continuous singing, with a level of organization and structure approaching that of typical breeding ground song. The songs, produced either by the tagged animals or close associates, shared phrase types and theme structure with one another, and some song bouts lasted close to an hour. Dive behavior of tagged animals during the time of sound production showed song occurring during periods of active diving, sometimes to depths greater than 100 m. One tag record also contained song in the presence of feeding lunges identified from the behavioral sensors, indicating that mating displays occur in areas worthy of foraging. These data show behavioral flexibility as the humpbacks manage competing needs to continue to feed and to prepare for the breeding season during late fall. This may also signify an ability to engage in breeding activities outside of the traditional, warm water breeding ground locations. PMID:23284666

Late-Preterm Birth, Maternal Symptomatology, and Infant Negativity

PubMed Central

Voegtline, Kristin M.; Stifter, Cynthia A.

2010-01-01

The present study examined infant negativity and maternal symptomatology by term status in a predominately low-income, rural sample of 132 infants (66 late-preterm) and their mothers. Late-preterm and term infants were group-matched by race, income, and maternal age. Maternal depression and anxiety symptoms were measured with the Brief Symptom Inventory 18 (BSI-18) when infants were 2 and 6 months of age. Also at 6 months, infant negativity was assessed by global observer ratings, maternal ratings, and microanalytic behavioral coding of fear and frustration. Results indicate that after controlling for infant age, late-preterm status predicted higher ratings of infant negativity by mothers, but not by global observers or microanalytic coding, despite a positive association in negativity across the three measures. Further, mothers of late-preterm infants reported more elevated and chronic co-morbid symptoms of depression and anxiety, which in turn, was related to concurrent maternal ratings of their infant’s negativity. Mothers response to late-preterm birth and partiality in the assessment of their infant’s temperament is discussed. PMID:20732715

Cognitive-Behavioral Therapy for Depression in an Older Gay Man: A Clinical Case Study

ERIC Educational Resources Information Center

Satterfield, Jason M.; Crabb, Rebecca

2010-01-01

Although strong evidence supports cognitive-behavioral therapy for late-life depression and depression in racial and ethnic minorities, there are no empirical studies on the treatment of depression in older sexual minorities. Three distinct literatures were tapped to create a depression treatment protocol for an older gay male. Interventions were…

Early-Childhood Poverty and Adult Attainment, Behavior, and Health

ERIC Educational Resources Information Center

Duncan, Greg J.; Ziol-Guest, Kathleen M.; Kalil, Ariel

2010-01-01

This article assesses the consequences of poverty between a child's prenatal year and 5th birthday for several adult achievement, health, and behavior outcomes, measured as late as age 37. Using data from the Panel Study of Income Dynamics (1,589) and controlling for economic conditions in middle childhood and adolescence, as well as demographic…

Sleep and Adjustment in Preschool Children: Sleep Diary Reports by Mothers Relate to Behavior Reports by Teachers.

ERIC Educational Resources Information Center

Bates, John E.; Viken, Richard J.; Alexander, Douglas B.; Beyers, Jennifer; Stockton, Lesley

2002-01-01

Investigated the relationship between sleep patterns and behavioral adjustment with 4- to 5-year-old children from low-income families. Found that disrupted child sleep patterns, including variability in parentally reported amount of sleep, variability in bedtime, and lateness of bedtime, predicted less optimal adjustment in preschool, even after…

Which Variables Predict Teachers Diagnostic Competence When Diagnosing Students' Learning Behavior at Different Stages of a Teacher's Career?

ERIC Educational Resources Information Center

Klug, Julia; Bruder, Simone; Schmitz, Bernhard

2016-01-01

Diagnosing is one of teachers' key competences. Lately, a new model of teachers' diagnostic competence and therewith a new measurement method focusing on diagnosing students' learning behavior in an interdisciplinary approach have been developed. They can build a basis for promoting teachers' diagnostic competence. However, some questions relevant…

Perceptions of Workplace Mentoring Behaviors for Lifelong Career Development

ERIC Educational Resources Information Center

Key, Lynne A.

2013-01-01

This study's purpose was to investigate the importance of mentoring functions and behaviors for lifelong career development as perceived by protégés. The population included individuals in middle to late adulthood (age 40 years and older) who reported they had been a protege in at least one mentoring association perceived as beneficial to their…

Assessing the Interpersonal Circumplex Model in Late Childhood: The Interpersonal Behavior Questionnaire for Children

ERIC Educational Resources Information Center

Di Blas, Lisa; Grassi, Michele; Luccio, Riccardo; Momente, Silvia

2012-01-01

The authors developed the Interpersonal Behavior Questionnaire for Children with the aim of assessing the constructs of the interpersonal circumplex model, that is, Dominance and Love and their possible combinations, via third- to fifth-grade children's self- and peer reports. In the three studies presented herein, the authors examined several…

Disorganized Behavior in Adolescent-Parent Interaction: Relations to Attachment State of Mind, Partner Abuse, and Psychopathology

ERIC Educational Resources Information Center

Obsuth, Ingrid; Hennighausen, Katherine; Brumariu, Laura E.; Lyons-Ruth, Karlen

2014-01-01

Disoriented, punitive, and caregiving/role-confused attachment behaviors are associated with psychopathology in childhood, but have not been assessed in adolescence. A total of 120 low-income late adolescents (aged 18-23 years) and parents were assessed in a conflict-resolution paradigm. Their interactions were coded with the Goal-Corrected…

Chemical stimulation of the lateral hypothalamus by carbachol attenuated the formalin-induced pain behaviors in rats.

PubMed

Ezzatpanah, Somayeh; Babapour, Vahab; Sadeghi, Bahman; Haghparast, Abbas

2015-02-01

Electrical and chemical stimulation of the lateral hypothalamus (LH) produces analgesia. Previous studies emphasized the importance of LH in the modulation of nociceptive behaviors in the acute pain models. In the current study, for the first time, we examined the effect of direct chemical stimulation of the LH with cholinergic receptor agonist, carbachol, on pain-related behaviors in the formalin test as a model of persistent inflammatory pain. Forty-eight adult male Wistar rats were implanted unilaterally with cannula into the LH. Four doses of carbachol (62.5, 125, 250 and 500 nM/0.5 μl saline) were microinjected into the LH just 5 min before the formalin test. Vehicle group received 0.5 μl saline into the LH. Pain-related behaviors were quantified and monitored in 5-min blocks for 60 min test period. Average nociceptive scores and area under the curve (AUC) as raw pain scores × time by the linear trapezoidal method were used for the statistical analyses. One important finding of our study was that carbachol blocks the nociceptive responses in both phases of formalin-induced nociception in a dose-dependent manner. Altogether, the percentage decrease of AUC values calculated for treatment groups, compared to the control group, was more significant in the late phase than the early phase. These findings suggest that LH modulates formalin-induced nociception through spinal and/or supraspinal sites. Copyright © 2014 Elsevier Inc. All rights reserved.

Entanglement tsunami: universal scaling in holographic thermalization.

PubMed

Liu, Hong; Suh, S Josephine

2014-01-10

We consider the time evolution of entanglement entropy after a global quench in a strongly coupled holographic system, whose subsequent equilibration is described in the gravity dual by the gravitational collapse of a thin shell of matter resulting in a black hole. In the limit of large regions of entanglement, the evolution of entanglement entropy is controlled by the geometry around and inside the event horizon of the black hole, resulting in regimes of pre-local-equilibration quadratic growth (in time), post-local-equilibration linear growth, a late-time regime in which the evolution does not carry memory of the size and shape of the entangled region, and a saturation regime with critical behavior resembling those in continuous phase transitions. Collectively, these regimes suggest a picture of entanglement growth in which an "entanglement tsunami" carries entanglement inward from the boundary. We also make a conjecture on the maximal rate of entanglement growth in relativistic systems.

Growth and Morphology of Phase Separating Supercritical Fluids

NASA Technical Reports Server (NTRS)

Hegseth, John; Beysens, Daniel; Perrot, Francoise; Nikolayev, Vadim; Garrabos, Yves

1996-01-01

The scientific objective is to study the relation between the morphology and the growth kinetics of domains during phase separation. We know from previous experiments performed near the critical point of pure fluids and binary liquids that there are two simple growth laws at late times. The 'fast' growth appears when the volumes of the phases are nearly equal and the droplet pattern is interconnected. In this case the size of the droplets grows linearly in time. The 'slow' growth appears when the pattern of droplets embedded in the majority phase is disconnected. In this case the size of the droplets increases in proportion to time to the power 1/3. The volume fraction of the minority phase is a good candidate to determine this change of behavior. All previous attempts to vary the volume fraction in a single experimental cell have failed because of the extreme experimental difficulties.

Is Travel Time to Colonoscopy Associated With Late-Stage Colorectal Cancer Among Medicare Beneficiaries in Iowa?

PubMed

Charlton, Mary E; Matthews, Kevin A; Gaglioti, Anne; Bay, Camden; McDowell, Bradley D; Ward, Marcia M; Levy, Barcey T

2016-09-01

Colorectal cancer (CRC) screening has been shown to decrease the incidence of late-stage colorectal cancer, yet a substantial proportion of Americans do not receive screening. Those in rural areas may face barriers to colonoscopy services based on travel time, and previous studies have demonstrated lower screening among rural residents. Our purpose was to assess factors associated with late-stage CRC, and specifically to determine if longer travel time to colonoscopy was associated with late-stage CRC among an insured population in Iowa. SEER-Medicare data were used to identify individuals ages 65 to 84 years old diagnosed with CRC in Iowa from 2002 to 2009. The distance between the centroid of the ZIP code of residence and the ZIP code of colonoscopy was computed for each individual who had continuous Medicare fee-for-service coverage for a 3- to 4-month period prior to diagnosis, and a professional claim for colonoscopy within that time frame. Demographic characteristics and travel times were compared between those diagnosed with early- versus late-stage CRC. Also, demographic differences between those who had colonoscopy claims identified within 3-4 months prior to diagnosis (81%) were compared to patients with no colonoscopy claims identified (19%). A total of 5,792 subjects met inclusion criteria; 31% were diagnosed with early-stage versus 69% with late-stage CRC. Those divorced or widowed (vs married) were more likely to be diagnosed with late-stage CRC (OR: 1.20, 95% CI: 1.06-1.37). Travel time was not associated with diagnosis of late-stage CRC. Among a Medicare-insured population, there was no relationship between travel time to colonoscopy and disease stage at diagnosis. It is likely that factors other than distance to colonoscopy present more pertinent barriers to screening in this insured population. Additional research should be done to determine reasons for nonadherence to screening among those with access to CRC screening services, given that over two-thirds of these insured individuals were diagnosed with late-stage CRC. © 2015 National Rural Health Association.

The income and health effects of tribal casino gaming on American Indians.

PubMed

Wolfe, Barbara; Jakubowski, Jessica; Haveman, Robert; Courey, Marissa

2012-05-01

The legalization of American Indian casino gaming in the late 1980s allows examination of the relationship between income and health in a quasi-experimental way. Revenue from gaming accrues to individual tribes and has been used both to supplement tribe members' income and to finance tribal infrastructure. We assembled annual data from 1988-2003 on tribal gaming, health care access (from the Area Resource File), and individual health and socioeconomic characteristics data (from the Behavioral Risk Factors Surveillance System). We use this information within a structural, difference-in-differences framework to study the effect of casino gaming on tribal members' income, health status, access to health care, and health-related behaviors. Our difference-in-differences framework relies on before-after comparisons among American Indians whose tribe has at some time operated a casino and with-without comparisons between American Indians whose tribe has and those whose tribe has not initiated gaming. Our results provide identified estimates of the positive effect of gaming on American Indian income and on several indicators of American Indian health, health-related behaviors, and access to health care.

Molecular insights into human daily behavior

PubMed Central

Brown, Steven A.; Kunz, Dieter; Dumas, Amelie; Westermark, Pål O.; Vanselow, Katja; Tilmann-Wahnschaffe, Amely; Herzel, Hanspeter; Kramer, Achim

2008-01-01

Human beings exhibit wide variation in their timing of daily behavior. We and others have suggested previously that such differences might arise because of alterations in the period length of the endogenous human circadian oscillator. Using dermal fibroblast cells from skin biopsies of 28 subjects of early and late chronotype (11 “larks” and 17 “owls”), we have studied the circadian period lengths of these two groups, as well as their ability to phase-shift and entrain to environmental and chemical signals. We find not only period length differences between the two classes, but also significant changes in the amplitude and phase-shifting properties of the circadian oscillator among individuals with identical “normal” period lengths. Mathematical modeling shows that these alterations could also account for the extreme behavioral phenotypes of these subjects. We conclude that human chronotype may be influenced not only by the period length of the circadian oscillator, but also by cellular components that affect its amplitude and phase. In many instances, these changes can be studied at the molecular level in primary dermal cells. PMID:18227513

Influence of Aggression on Information Processing in the Emotional Stroop Task – an Event-Related Potential Study

PubMed Central

Bertsch, Katja; Böhnke, Robina; Kruk, Menno R.; Naumann, Ewald

2009-01-01

Aggression is a common behavior which has frequently been explained as involving changes in higher level information processing patterns. Although researchers have started only recently to investigate information processing in healthy individuals while engaged in aggressive behavior, the impact of aggression on information processing beyond an aggressive encounter remains unclear. In an event-related potential study, we investigated the processing of facial expressions (happy, angry, fearful, and neutral) in an emotional Stroop task after experimentally provoking aggressive behavior in healthy participants. Compared to a non-provoked group, these individuals showed increased early (P2) and late (P3) positive amplitudes for all facial expressions. For the P2 amplitude, the effect of provocation was greatest for threat-related expressions. Beyond this, a bias for emotional expressions, i.e., slower reaction times to all emotional expressions, was found in provoked participants with a high level of trait anger. These results indicate significant effects of aggression on information processing, which last beyond the aggressive encounter even in healthy participants. PMID:19826616

Early Callous-Unemotional Behavior, Theory-of-mind, and a Fearful/Inhibited Temperament Predict Externalizing Problems in Middle and Late Childhood

PubMed Central

Song, Ju-Hyun; Waller, Rebecca; Hyde, Luke W.; Olson, Sheryl L.

2016-01-01

Childhood externalizing problems are more likely to be severe and persistent when combined with high levels of callous-unemotional (CU) behavior. A handful of recent studies have shown that CU behavior can also be reliably measured in the early preschool years, which may help to identify young children who are less likely to desist from early externalizing behaviors. The current study extends previous literature by examining the role of CU behavior in very early childhood in the prediction of externalizing problems in both middle and late childhood, and tests whether other relevant child characteristics, including Theory-of-Mind (ToM) and fearful/inhibited temperament moderate these pathways. Multi-method data, including parent reports of child CU behavior and fearful/inhibited temperament, observations of ToM, and teacher-reported externalizing problems were drawn from a prospective, longitudinal study of children assessed at ages 3, 6, and 10 (N=241; 48% female). Results demonstrated that high levels of CU behavior predicted externalizing problems at ages 6 and 10 over and above the effect of earlier externalizing problems at age 3, but that these main effects were qualified by two interactions. High CU behavior was related to higher levels of externalizing problems specifically for children with low ToM and a low fearful/inhibited temperament. The results show that a multitude of child characteristics likely interact across development to increase or buffer risk for child externalizing problems. These findings can inform the development of targeted early prevention and intervention for children with high CU behavior. PMID:26582182

Early Callous-Unemotional Behavior, Theory-of-Mind, and a Fearful/Inhibited Temperament Predict Externalizing Problems in Middle and Late Childhood.

PubMed

Song, Ju-Hyun; Waller, Rebecca; Hyde, Luke W; Olson, Sheryl L

2016-08-01

Childhood externalizing problems are more likely to be severe and persistent when combined with high levels of callous-unemotional (CU) behavior. A handful of recent studies have shown that CU behavior can also be reliably measured in the early preschool years, which may help to identify young children who are less likely to desist from early externalizing behaviors. The current study extends previous literature by examining the role of CU behavior in very early childhood in the prediction of externalizing problems in both middle and late childhood, and tests whether other relevant child characteristics, including Theory-of-Mind (ToM) and fearful/inhibited temperament moderate these pathways. Multi-method data, including parent reports of child CU behavior and fearful/inhibited temperament, observations of ToM, and teacher-reported externalizing problems were drawn from a prospective, longitudinal study of children assessed at ages 3, 6, and 10 (N = 241; 48 % female). Results demonstrated that high levels of CU behavior predicted externalizing problems at ages 6 and 10 over and above the effect of earlier externalizing problems at age 3, but that these main effects were qualified by two interactions. High CU behavior was related to higher levels of externalizing problems specifically for children with low ToM and a low fearful/inhibited temperament. The results show that a multitude of child characteristics likely interact across development to increase or buffer risk for child externalizing problems. These findings can inform the development of targeted early prevention and intervention for children with high CU behavior.

[Dropout behavior during inpatient psychotherapy ].

PubMed

Martens, Ute; Rempel, Irene; Zipfel, Stephan; Enck, Paul; Teufel, Martin

2014-01-01

Dropouts result in far-reaching consequences for the individual patient, fellow patients, therapists, and the clinic. This study was aimed at early identification of patients with a dropout risk. Data from patients of the Department of Psychosomatic Medicine and Psychotherapy of the Medical University Clinic of Tübingen (Germany) were analyzed retrospectively in a case-control study (matched). Differences in the results of various questionnaires (SCL-90-R, IIP-D, SF-36) regarding reasons for dropout and sociodemographic data were analyzed. A total of 59 dropouts, 50 females and 9 males, were included. They were split into 28 early dropouts and 31 late dropouts. The data were compared between early and late dropouts and control group. Early dropouts were significantly younger than late dropouts; they tended to live with their parents or on their own, and suffered more frequently from eating disorders. Late dropouts lived together with partners and suffered from somatoform disorders more frequently than early dropouts. The reasons given for dropout did not differ between the groups. No differences between dropouts and the controls were found with respect to psychopathology (SCL- 90-R) and quality of life (SF-36). Late dropouts did show significantly lower scores on the scale "autocracy/dominance" than the controls (IIP). Therapy dropout is a multifactorial occurrence. It is generally not predictable, though it may be predicted with different instruments on the basis of a diagnosis, especially with respect to interpersonal behavior patterns. In further studies, targeted interventions should be developed and tested which enable procedures to minimize the risk of dropout and to achieve complete treatment according to patients' intentions.

Minimal microwave anisotrophy from perturbations induced at late times

NASA Technical Reports Server (NTRS)

Jaffe, Andrew H.; Stebbins, Albert; Frieman, Joshua A.

1994-01-01

Aside from primordial gravitational instability of the cosmological fluid, various mechanisms have been proposed to generate large-scale structure at relatively late times, including, e.g., 'late-time' cosmological phase transitions. In these scenarios, it is envisioned that the universe is nearly homogeneous at the times of last scattering and that perturbations grow rapidly sometimes after the primordial plasma recombines. On this basis, it was suggested that large inhomogeneities could be generated while leaving relatively little imprint on the cosmic microwave background (MBR) anisotropy. In this paper, we calculate the minimal anisotropies possible in any 'late-time' scenario for structure formation, given the level of inhomogeneity observed at present. Since the growth of the inhomogeneity involves time-varying gravitational fields, these scenarios inevitably generate significant MBR anisotropy via the Sachs-Wolfe effect. Moreover, we show that the large-angle MBR anisotropy produced by the rapid post-recombination growth of inhomogeneity is generally greater than that produced by the same inhomogeneity growth via gravitational instability. In 'realistic' scenarios one can decrease the anisotropy compared to models with primordial adiabatic fluctuations, but only on very small angular scales. The value of any particular measure of the anisotropy can be made small in late-time models, but only by making the time-dependence of the gravitational field sufficiently 'pathological'.

Development of constructivist theory of mind from middle childhood to early adulthood and its relation to social cognition and behavior.

PubMed

Weimer, Amy A; Parault Dowds, Susan J; Fabricius, William V; Schwanenflugel, Paula J; Suh, Go Woon

2017-02-01

Two studies examined the development of constructivist theory of mind (ToM) during late childhood and early adolescence. In Study 1, a new measure was developed to assess participants' understanding of the interpretive and constructive processes embedded in memory, comprehension, attention, comparison, planning, and inference. Using this measure, Study 2 tested a mediational model in which prosocial reasoning about conflict mediated the relation between constructivist ToM and behavior problems in high school. Results showed that the onset of constructivist ToM occurs between late childhood and early adolescence and that adolescents who have more advanced constructivist ToM have more prosocial reasoning about conflict, which in turn mediated the relation with fewer serious behavior problems in high school, after controlling for academic performance and sex. In both studies, girls showed more advanced constructivist ToM than boys in high school. Copyright © 2016 Elsevier Inc. All rights reserved.

A working model for the assessment of disruptions in social behavior among aged rats: the role of sex differences, social recognition, and sensorimotor processes

PubMed Central

Perkins, Amy E.; Doremus-Fitzwater, Tamara L.; Spencer, Robert L.; Varlinskaya, Elena I.; Conti, Melissa M.; Bishop, Chris; Deak, Terrence

2016-01-01

Aging results in a natural decline in social behavior, yet little is known about the processes underlying these changes. Engaging in positive social interaction is associated with many health benefits, including reduced stress reactivity, and may serve as a potential buffer against adverse consequences of aging. The goal of these studies was to establish a tractable model for the assessment of social behavior deficits associated with late aging. Thus, in Exp. 1, 1.5-, 3-, and 18-month-old male Fischer 344 (F344) rats were assessed for object investigation, and social interaction with a same-aged partner (novel/familiar), or a different-aged partner, thereby establishing working parameters for studies that followed. Results revealed that 18-month-old males exhibited reductions in social investigation and social contact behavior, with this age-related decline not influenced by familiarity or age of the social partner. Subsequently, Exp. 2 extended assessment of social behavior to both male and female F344 rats at multiple ages (3, 9, 18, and 24 months), after which a series of sensorimotor performance tests were conducted. In this study, both males and females exhibited late aging-related reductions in social interactions, but these changes were more pronounced in females. Additionally, sensorimotor performance was shown to be impaired in 24-month-olds, but not 18-month-olds, with this deficit more evident in males. Finally, Exp. 3 examined whether aging-related inflammation could account for declines in social behavior during late aging by administering naproxen (0, 7, 14, and 28 mg/kg; s.c.)—a non-steroidal anti-inflammatory drug—to 18-month-old females. Results from this study revealed that social behavior was unaffected by acute or repeated (6 days) naproxen, suggesting that aging-related social deficits in females may not be a consequence of a general aging-related inflammation and/or malaise. Together, these findings demonstrate that aging-related declines in social behavior are (i) specific to social stimuli and (ii) not indicative of a general state of aging-related debilitation. Thus, these findings establish working parameters for a highly tractable model in which the neural and hormonal mechanisms underlying aging-related declines in social behavior can be examined. PMID:26811912

A working model for the assessment of disruptions in social behavior among aged rats: The role of sex differences, social recognition, and sensorimotor processes.

PubMed

Perkins, Amy E; Doremus-Fitzwater, Tamara L; Spencer, Robert L; Varlinskaya, Elena I; Conti, Melissa M; Bishop, Christopher; Deak, Terrence

2016-04-01

Aging results in a natural decline in social behavior, yet little is known about the processes underlying these changes. Engaging in positive social interaction is associated with many health benefits, including reduced stress reactivity, and may serve as a potential buffer against adverse consequences of aging. The goal of these studies was to establish a tractable model for the assessment of social behavior deficits associated with late aging. Thus, in Exp. 1, 1.5-, 3-, and 18-month-old male Fischer 344 (F344) rats were assessed for object investigation, and social interaction with a same-aged partner (novel/familiar), or a different-aged partner, thereby establishing working parameters for studies that followed. Results revealed that 18-month-old males exhibited reductions in social investigation and social contact behavior, with this age-related decline not influenced by familiarity or age of the social partner. Subsequently, Exp. 2 extended assessment of social behavior to both male and female F344 rats at multiple ages (3, 9, 18, and 24 months), after which a series of sensorimotor performance tests were conducted. In this study, both males and females exhibited late aging-related reductions in social interactions, but these changes were more pronounced in females. Additionally, sensorimotor performance was shown to be impaired in 24-month-olds, but not 18-month-olds, with this deficit more evident in males. Finally, Exp. 3 examined whether aging-related inflammation could account for declines in social behavior during late aging by administering naproxen (0, 7, 14, and 28 mg/kg; s.c.)-a non-steroidal anti-inflammatory drug-to 18-month-old females. Results from this study revealed that social behavior was unaffected by acute or repeated (6 days) naproxen, suggesting that aging-related social deficits in females may not be a consequence of a general aging-related inflammation and/or malaise. Together, these findings demonstrate that aging-related declines in social behavior are (i) specific to social stimuli and (ii) not indicative of a general state of aging-related debilitation. Thus, these findings establish working parameters for a highly tractable model in which the neural and hormonal mechanisms underlying aging-related declines in social behavior can be examined. Copyright © 2016 Elsevier Inc. All rights reserved.

Forecasting consequences of changing sea ice availability for Pacific walruses

USGS Publications Warehouse

Udevitz, Mark S.; Jay, Chadwick V.; Taylor, Rebecca; Fischbach, Anthony S.; Beatty, William S.; Noren, Shawn R.

2017-01-01

The accelerating rate of anthropogenic alteration and disturbance of environments has increased the need for forecasting effects of environmental change on fish and wildlife populations. Models linking projections of environmental change with behavioral responses and bioenergetic effects can provide a basis for these forecasts. There is particular interest in forecasting effects of projected reductions in sea ice availability on Pacific walruses (Odobenus rosmarus divergens). Declining extent of summer sea ice in the Chukchi Sea has caused Pacific walruses to increase use of coastal haulouts and decrease use of more productive offshore feeding areas. Such climate-induced changes in distribution and behavior could ultimately affect the status of the population. We developed behavioral models to relate changes in sea ice availability to adult female walrus movements and activity levels, and adapted previously developed bioenergetics models to relate those activity levels to energy requirements and the ability to meet those requirements. We then linked these models to general circulation model projections of future ice availability to forecast autumn body condition for female walruses during mid- and late-century time periods. Our results suggest that as sea ice becomes less available in the Chukchi Sea, female walruses will spend more time in the southwestern region of that sea, less time resting, and less time foraging. Median forecasted autumn body masses were 7–12% lower in future scenarios than during recent times, but posterior distributions broadly overlapped and median forecasted seasonal mass losses (15–34%) were comparable to seasonal mass losses routinely experienced by other pinnipeds. These seasonal reductions in body condition would be unlikely to result in demographic effects, but if walruses were unable to rebuild endogenous reserves while wintering in the Bering Sea, cumulative effects could have implications for reproduction and survival, ultimately affecting the status of the Pacific walrus population. Our approach provides a general framework for forecasting consequences of the broad range of environmental changes and anthropogenic disturbances that may affect bioenergetics through behavioral responses or changes in prey availability.

Late presentation of canine nasal tumours in a UK referral hospital and treatment outcomes.

PubMed

Mason, S L; Maddox, T W; Lillis, S M; Blackwood, L

2013-07-01

To determine the computed tomographic stage of dogs with nasal tumours in a UK referral population, and whether stage, time to referral and treatment correlates with outcome. Retrospective review of clinical records and computed tomography scans of dogs with nasal tumours. Dogs (n=78) presented to a referral practice in the UK with suspected nasal tumours are presented with more late stage tumours than dogs in the USA and Japan. Length of time from initial presentation to referral did not correlate with tumour stage at diagnosis. Median survival times for radiotherapy-treated dogs in this population are equivalent to those previously reported for late stage nasal tumours. Dogs with nasal tumours are presented late in the course of disease in the North West of England. Dogs with clinical signs consistent with a nasal tumour should have timely imaging and biopsy, in order to make prompt treatment decisions. Although survival times are comparable with previous reports and radiotherapy is a valid treatment option for dogs with late stage disease, better outcomes are likely to be achievable with earlier treatment. © 2013 British Small Animal Veterinary Association.

Sleep and meal-time misalignment alters functional connectivity: a pilot resting-state study.

PubMed

Yoncheva, Y N; Castellanos, F X; Pizinger, T; Kovtun, K; St-Onge, M-P

2016-11-01

Delayed sleep and meal times promote metabolic dysregulation and obesity. Altered coordination of sleeping and eating times may impact food-reward valuation and interoception in the brain, yet the independent and collective contributions of sleep and meal times are unknown. This randomized, in-patient crossover study experimentally manipulates sleep and meal times while preserving sleep duration (7.05±0.44 h for 5 nights). Resting-state functional magnetic resonance imaging scans (2 × 5-minute runs) were obtained for four participants (three males; 25.3±4.6 years), each completing all study phases (normal sleep/normal meal; late sleep/normal meal; normal sleep/late meal; and late sleep/late meal). Normal mealtimes were 1, 5, 11 and 12.5 h after awakening; late mealtimes were 4.5, 8.5, 14.5 and 16 h after awakening. Seed-based resting-state functional connectivity (RSFC) was computed for a priori regions-of-interest (seeds) and contrasted across conditions. Statistically significant (P<0.05, whole-brain corrected) regionally specific effects were found for multiple seeds. The strongest effects were linked to the amygdala: increased RSFC for late versus normal mealtimes (equivalent to skipping breakfast). A main effect of sleep and interaction with meal time were also observed. Preliminary findings support the feasibility of examining the effects of sleep and meal-time misalignment, independent of sleep duration, on RSFC in regions relevant to food reward and interoception.

Toxic cocaine- and convulsant-induced modification of forced swimming behaviors and their interaction with ethanol: comparison with immobilization stress

PubMed Central

Hayase, Tamaki; Yamamoto, Yoshiko; Yamamoto, Keiichi

2002-01-01

Background Swimming behaviors in the forced swimming test have been reported to be depressed by stressors. Since toxic convulsion-inducing drugs related to dopamine [cocaine (COC)], benzodiazepine [methyl 6,7-dimethoxy-4-ethyl-β-carboline-carboxylate (DMCM)], γ-aminobutyric acid (GABA) [bicuculline (BIC)], and glutamate [N-methyl-D-aspartate (NMDA)] receptors can function as stressors, the present study compared their effects on the forced swimming behaviors with the effects of immobilization stress (IM) in rats. Their interactions with ethanol (EtOH), the most frequently coabused drug with COC which also induces convulsions as withdrawal symptoms but interferes with the convulsions caused by other drugs, were also investigated. Results Similar to the IM (10 min) group, depressed swimming behaviors (attenuated time until immobility and activity counts) were observed in the BIC (5 mg/kg IP) and DMCM (10 mg/kg IP) groups at the 5 h time point, after which no toxic behavioral symptoms were observed. However, they were normalized to the control levels at the 12 h point, with or without EtOH (1.5 g/kg IP). In the COC (60 mg/kg IP) and NMDA (200 mg/kg IP) groups, the depression occurred late (12 h point), and was normalized by the EtOH cotreatment. At the 5 h point, the COC treatment enhanced the swimming behaviors above the control level. Conclusions Although the physiological stress (IM), BIC, and DMCM also depressed the swimming behaviors, a delayed occurrence and EtOH-induced recovery of depressed swimming were observed only in the COC and NMDA groups. This might be correlated with the previously-reported delayed responses of DA and NMDA neurons rather than direct effects of the drugs, which could be suppressed by EtOH. Furthermore, the characteristic psychostimulant effects of COC seemed to be correlated with an early enhancement of swimming behaviors. PMID:12425723

Are Late College Applicants Different? Survey of Fall Applicants, 1979, Reedley College.

ERIC Educational Resources Information Center

Clark, Robert M.

A study was conducted at Reedley College to determine whether there were any significant differences between first-time students who applied for admission on time and those who applied late, i.e., from the week prior to the beginning of instruction through the third week of the semester. Involved in the study were the 200 late applicants for the…

Effects of Multiple Maternal Relationship Transitions on Offspring Antisocial Behavior in Childhood and Adolescence: A Cousin-Comparison Analysis

PubMed Central

Goodnight, Jackson A.; D’Onofrio, Brian M.; Cherlin, Andrew J.; Emery, Robert E.; Van Hulle, Carol A.; Lahey, Benjamin B.

2012-01-01

Previous studies of the association between multiple parental relationship transitions (i.e., when a parent begins or terminates an intimate relationship involving cohabitation) and offspring antisocial behavior have varied in their efforts to rule out confounding influences, such as parental antisocial behavior and low income. They also have been limited in the representativeness of their samples. Thus, it remains unclear to what degree parents’ multiple relationship transitions have independent effects on children’s antisocial behavior. Analyses were conducted using data on 8,652 6–9-year-old, 6,911 10–13-year-old, and 6,495 14-17-year-old offspring of a nationally representative sample of U.S. women. Cousin-comparisons were used in combination with statistical covariates to evaluate the associations between maternal relationship transitions and offspring antisocial behavior in childhood and adolescence. Cousin-comparisons suggested that associations between maternal relationship transitions and antisocial behavior in childhood and early adolescence are largely explained by confounding factors. In contrast, the associations between maternal relationship transitions and offspring delinquency in late adolescence were robust to measured and unmeasured confounds. The present findings suggest that interventions aimed at reducing exposure to parental relationship transitions or addressing the psychosocial consequences of exposure to parental relationship transitions could reduce risk for offspring delinquency in late adolescence. PMID:22829173

Maternal treatment with picrotoxin in late pregnancy improved female sexual behavior but did not alter male sexual behavior of offspring.

PubMed

Bernardi, Maria M; Scanzerla, Kayne K; Chamlian, Mayra; Teodorov, Elizabeth; Felicio, Luciano F

2013-08-01

Previous studies from our laboratory investigated the effects of picrotoxin (PT), a γ-aminobutyric acid receptor antagonist administered during several perinatal periods, on the sexual behavior of male and female rats. We observed that the time of perinatal exposure to PT is critical to determine either facilitation or impairment of sexual behavior. The present study evaluated the effects of prenatal administration of a single dose of PT on gestation day 18 of dams (the first critical period of male brain sexual differentiation) on sexual behavior of male and female offspring. Thus, female Wistar rats were mated with males and, on gestation day 18, received 0.6 mg/kg of PT or 0.9% saline solution subcutaneously. On postnatal day 1, the offspring were weighed and several measures of sexual development were assessed. The sexual behaviors and the general activity in the open field of adult male and ovariectomized, hormone-treated female rats were observed. On comparison with the control group, maternal PT treatment: (i) did not alter the maternal weight, pup weight, anogenital distance, or male and female general activity; (ii) increased female sexual behavior, that is, decreased the latencies to first mount, first lordosis, and tenth lordosis, and the percentage of females presenting lordosis; and (iii) did not alter male sexual behavior. It is suggested that prenatal PT exposure interfered with epigenetic mechanisms related to the development of sex differences in the brain, leading to the observed sexually dimorphic effects on sexual behavior.

Time of day influences the voluntary intake and behavioral response to methamphetamine and food reward.

PubMed

Keith, Diana R; Hart, Carl L; Robotham, Margaret; Tariq, Maliha; Le Sauter, Joseph; Silver, Rae

2013-09-01

The circadian timing system influences a vast array of behavioral responses. Substantial evidence indicates a role for the circadian system in regulating reward processing. Here we explore time of day effects on drug anticipation, locomotor activity, and voluntary methamphetamine (MA) and food intake in animals with ad libitum food access. We compared responses to drug versus a palatable treat during their normal sleep times in early day (zeitgeber time (ZT) 0400) or late day (ZT 1000). In the first study, using a between-subjects design, mice were given daily 1-h access to either peanut butter (PB-Alone) or to a low or high concentration of MA mixed in PB (MA+PB). In study 2, we repeated the experiment using a within-subjects design in which mice could choose between PB-Alone and MA+PB at either ZT 0400 or 1000. In study 3, the effects of MA-alone were investigated by evaluating anticipatory activity preceding exposure to nebulized MA at ZT 0400 vs. ZT 1000. Time of day effects were observed for both drug and palatable treat, such that in the between groups design, animals showed greater intake, anticipatory activity, and post-ingestional activity in the early day. Furthermore, there were differences among mice in the amount of MA ingested but individuals were self-consistent in their daily intake. The results for the within-subjects experiment also revealed robust individual differences in preference for MA+PB or PB-Alone. Interestingly, time of day effects on intake were observed only for the preferred substance. Anticipatory activity preceding administration of MA by nebulization was also greater at ZT 0400 than ZT 1000. Finally, pharmacokinetic response to MA administered intraperitoneally did not vary as a function of time of administration. The results indicate that time of day is an important variable mediating the voluntary intake and behavioral effects of reinforcers. Copyright © 2013 Elsevier Inc. All rights reserved.

Paradoxical physiological transitions from aging to late life in Drosophila.

PubMed

Shahrestani, Parvin; Quach, Julie; Mueller, Laurence D; Rose, Michael R

2012-02-01

In a variety of organisms, adulthood is divided into aging and late life, where aging is a period of exponentially increasing mortality rates and late life is a period of roughly plateaued mortality rates. In this study we used ∼57,600 Drosophila melanogaster from six replicate populations to examine the physiological transitions from aging to late life in four functional characters that decline during aging: desiccation resistance, starvation resistance, time spent in motion, and negative geotaxis. Time spent in motion and desiccation resistance declined less quickly in late life compared to their patterns of decline during aging. Negative geotaxis declined at a faster rate in late life compared to its rate of decline during aging. These results yield two key findings: (1) Late-life physiology is distinct from the physiology of aging, in that there is not simply a continuation of the physiological trends which characterize aging; and (2) late life physiology is complex, in that physiological characters vary with respect to their stabilization, deceleration, or acceleration in the transition from aging to late life. These findings imply that a correct understanding of adulthood requires identifying and appropriately characterizing physiology during properly delimited late-life periods as well as aging periods.

Paradoxical Physiological Transitions from Aging to Late Life in Drosophila

PubMed Central

Quach, Julie; Mueller, Laurence D.; Rose, Michael R.

2012-01-01

Abstract In a variety of organisms, adulthood is divided into aging and late life, where aging is a period of exponentially increasing mortality rates and late life is a period of roughly plateaued mortality rates. In this study we used ∼57,600 Drosophila melanogaster from six replicate populations to examine the physiological transitions from aging to late life in four functional characters that decline during aging: desiccation resistance, starvation resistance, time spent in motion, and negative geotaxis. Time spent in motion and desiccation resistance declined less quickly in late life compared to their patterns of decline during aging. Negative geotaxis declined at a faster rate in late life compared to its rate of decline during aging. These results yield two key findings: (1) Late-life physiology is distinct from the physiology of aging, in that there is not simply a continuation of the physiological trends which characterize aging; and (2) late life physiology is complex, in that physiological characters vary with respect to their stabilization, deceleration, or acceleration in the transition from aging to late life. These findings imply that a correct understanding of adulthood requires identifying and appropriately characterizing physiology during properly delimited late-life periods as well as aging periods. PMID:22233126

The Dynamics of an Ongoing Andesitic Eruption: What We Have Learned From Surface Deformation at Soufriere Hills Volcano, Montserrat, BWI

NASA Astrophysics Data System (ADS)

Mattioli, G.; Herd, R.; Aponte, M.; Dixon, T.; Jansma, P.; Smith, A.

2002-05-01

The Soufriere Hills volcano (SHV) CGPS network consists of 6 dual-frequency code-phase receivers, with Dorn-Margolin choke-ring antennae, which share a common RF telemetry network. All GPS data were processed using GIPSY-OASISII to obtain free-network point positions using final orbit, clock, and earth orientation parameters from JPL. Positions were recast into ITRF97 and these positions were used to calculate component velocities. Final site velocities for each site are reported relative a fixed Caribbean reference frame (DeMets et al., 2000). By examination of the individual time series of both the campaign and continuous sites, we have been able to divide the ground deformation observations in several distinct phases, correlated with the type of eruptive behavior manifested at the surface. While the CGPS data is limited in space, and has some important and substantial gaps because of equipment failures (some of which could not be fixed due to hazardous eruptive activity), we find that the entire GPS data set can be usefully discussed in terms of three distinct periods: (1) late 1995 to the end of 1997; (2) early 1998 to late 1999; and (3) early 2000 to the present. The primary criterion used for this distinction is the vertical velocity field. During the first period (1995-1997), all stations show strong subsidence as a function of radial distance from the SH dome (Mattioli et al., 1998). Although there is a data gap between late fall 1997 and the re-establishment of the CGPS network in early 1998, all sites show inflation at about half the rate observed for the previous period of subsidence. Thus periods of significant surface outflow (1995-1997) are strongly correlated with surface subsidence, while periods of no apparent surface magma flux are strongly correlated with ground surface inflation. Although the exact timing is somewhat equivocal, subsidence resumed at all CGPS sites just prior to the emergence of the Millennium Dome in late November to Early December 1999 and continues today. Data from each of the distinct periods has been inverted using a modified, downhill simplex method for an elastic half-space. Our code explicitly includes provision for a Mogi-type source and perpendicular opening across a planer dislocation (i.e. dike). All best-fit models have two distinct sub-surface pressure sources (deep Mogi and shallow dike oriented NW) whose initial geometry and magnitude were not fixed a priori. Inferred Mogi depths range from 4.5 to 6.0 km, with changing polarity in time, and the dimensions and inferred opening displacement of the dike have decreased from an initial maximum of ~1 m in each of the three periods. Our observations demonstrate that SHV is also affected by longer-period semi-periodic behavior, similar to that reported by Voight et al. (1998) for very short-period fluctuations on the order of 6-14 hr.

Weighing worth against uncertain work: The interplay of exhaustion, ambiguity, hope and disappointment in mothers breastfeeding late preterm infants

PubMed Central

Demirci, Jill Radtke; Happ, Mary Beth; Bogen, Debra L.; Albrecht, Susan A.; Cohen, Susan M.

2012-01-01

Poor breastfeeding outcomes among late preterm infants (LPIs) have been attributed to inadequate breast milk transfer stemming from physiological immaturities. However, breastfeeding is more than a biological phenomenon, and it is unclear how mothers of LPIs manage other factors that may also impact the breastfeeding course. Using grounded theory methods and incorporating serial postpartum interviews with several novel data collection techniques, we examined breastfeeding establishment over a 6–8 week period among 10 late preterm mother-infant dyads recruited from a maternity hospital in Pittsburgh, Pennsylvania, USA. We found that breastfeeding in the LPI population was a fluctuating, cascade-like progression of trial and error, influenced by a host of contextual factors and events and culminating with breastfeeding continuation (with or without future caveats for duration or exclusivity of breastfeeding) or cessation. The trajectory was explained by the basic psychosocial process Weighing Worth against Uncertain Work, which encompassed the tension between breastfeeding motivation, the intensity of breastfeeding work, and ambiguity surrounding infant behavior and feeding cues. Several sub-processes were also identified: Playing the Game; Letting Him be the Judge vs. Accommodating Both of Us; and Questioning Worth vs. Holding out Hope. If valid, our theoretical model indicates a need for earlier, more extensive, and more qualified breastfeeding support for mothers of late preterm infants that emphasizes the connection between prematurity and observed feeding behaviors. PMID:23020593

A Unique Assemblage of Engraved Plaquettes from Ein Qashish South, Jezreel Valley, Israel: Figurative and Non-Figurative Symbols of Late Pleistocene Hunters-Gatherers in the Levant

PubMed Central

Yaroshevich, Alla; Bar-Yosef, Ofer; Boaretto, Elisabeta; Caracuta, Valentina; Greenbaum, Noam; Porat, Naomi; Roskin, Joel

2016-01-01

Three engraved limestone plaquettes from the recently excavated Epipaleolithic open-air site Ein Qashish South in the Jezreel Valley, Israel comprise unique evidence for symbolic behavior of Late Pleistocene foragers in the Levant. The engravings, uncovered in Kebaran and Geometric Kebaran deposits (ca. 23ka and ca. 16.5ka BP), include the image of a bird—the first figurative representation known so far from a pre-Natufian Epipaleolithic—along with geometric motifs such as chevrons, crosshatchings and ladders. Some of the engravings closely resemble roughly contemporary European finds interpreted as "systems of notations" or "artificial memory systems"–records related to timing of seasonal resources and associated aggregation events of nomadic groups. Moreover, similarly looking signs and patterns are well known from the context of the local Natufian—a final Epipaleolithic culture of sedentary or semi-sedentary foragers who started practicing agriculture. The investigation of the engravings found in Ein Qashish South involves conceptualizations developed in studies of European and local parallels, a selection of ethnographic examples and preliminary microscopic observations of the plaquettes. This shows that the figurative and non-figurative images comprise a coherent assemblage of symbols that might have been applied in order to store, share and transmit information related to social and subsistence realms of mobile bands. It further suggests that the site functioned as a locality of groups' aggregation and indicates social complexity of pre-Natufian foragers in the Levant. While alterations in social and subsistence strategies can explain the varying frequency of image use characterizing different areas of the Late Pleistocene world—the apparent similarity in graphics and the mode of their application support the possibility that symbol-mediated behavior has a common and much earlier origin. PMID:27557110

Gender legacies of jung and freud as epistemology in emergent feminist research on late motherhood.

PubMed

Barone-Chapman, Maryann

2014-03-01

While conducting doctoral research in social science on late motherhood, two analytical engagements with the feminine came to my attention as evidence of a patriarchal bias toward the realm of womanhood. Jung's mythopoetic tension between symbolism and enactments with the feminine and Freud's supposition that a denial of the feminine was necessary for psychological and emotional development appeared to be perpetuating a social problem continuing in current times. Across affective behavior and narrative within stories of late procreative desire, dream journals and Word Association Tests of eight participants was the memory of a male sibling who had enjoyed primacy of place in the parental home over the daughter. The female body with a voice was missing in the one-sided perspectives of Analytical Psychology and Psychoanalysis on the subject of the feminine, until a whole view of psyche's discontents in Feminist inspired Psychoanalytic theories from both schools on the female body were included. Freud and Jung's views became evidence of patriarchy as background while extension of Feminist inspired psychoanalytical thinking, Queer theories and Creation Myth allowed new meanings of the embodied feminine to emerge through a recapitulation of a union of opposites as a union of epistemology and ethos. The essence of Jung's mid-life theories, altered by modernity and eclipsed by female advancement, remains replicatable and paradigmatic outside of essentialist gender performance.

Gender Legacies of Jung and Freud as Epistemology in Emergent Feminist Research on Late Motherhood

PubMed Central

Barone-Chapman, Maryann

2014-01-01

While conducting doctoral research in social science on late motherhood, two analytical engagements with the feminine came to my attention as evidence of a patriarchal bias toward the realm of womanhood. Jung’s mythopoetic tension between symbolism and enactments with the feminine and Freud’s supposition that a denial of the feminine was necessary for psychological and emotional development appeared to be perpetuating a social problem continuing in current times. Across affective behavior and narrative within stories of late procreative desire, dream journals and Word Association Tests of eight participants was the memory of a male sibling who had enjoyed primacy of place in the parental home over the daughter. The female body with a voice was missing in the one-sided perspectives of Analytical Psychology and Psychoanalysis on the subject of the feminine, until a whole view of psyche’s discontents in Feminist inspired Psychoanalytic theories from both schools on the female body were included. Freud and Jung’s views became evidence of patriarchy as background while extension of Feminist inspired psychoanalytical thinking, Queer theories and Creation Myth allowed new meanings of the embodied feminine to emerge through a recapitulation of a union of opposites as a union of epistemology and ethos. The essence of Jung’s mid-life theories, altered by modernity and eclipsed by female advancement, remains replicatable and paradigmatic outside of essentialist gender performance. PMID:25379265

A longitudinal study of the effects of child-reported maternal warmth on cortisol stress response 15 years after parental divorce

PubMed Central

Luecken, Linda J.; Hagan, Melissa J.; Wolchik, Sharlene A.; Sandler, Irwin N.; Tein, Jenn-Yun

2015-01-01

Objective Childhood parental divorce is associated with an increased risk of behavioral and physical health problems. Alterations in adrenocortical activity may be a mechanism in this relation. Parent-child relationships have been linked to cortisol regulation in children exposed to adversity, but prospective research is lacking. We examined maternal warmth in adolescence as a predictor of young adults’ cortisol stress response 15 years after parental divorce. Methods Participants included 240 youth from recently divorced families. Mother and child reports of maternal warmth were assessed at 6 time points across childhood, adolescence, and young adulthood. Offspring salivary cortisol was measured in young adulthood before and after a social stress task. Structural equation modeling was used to predict cortisol response from maternal warmth across early and late adolescence. Results Higher child-reported maternal warmth in early adolescence predicted higher child-reported maternal warmth in late adolescence (std. regression = .45, SE = .065, p < .01), which predicted lower cortisol response to a challenging interpersonal task in young adulthood (std. regression = −.20, SE = .094, p = .031). Neither mother-reported warmth in early adolescence nor late adolescence was significantly related to offspring cortisol response in young adulthood. Conclusions Results suggest that for children from divorced families, a warm mother-child relationship post-divorce and across development, as perceived by the child, may promote efficient biological regulation later in life. PMID:26465217

Effects of late quaternary climate change on Palearctic shrews.

PubMed

Prost, Stefan; Klietmann, Johannes; van Kolfschoten, Thijs; Guralnick, Robert P; Waltari, Eric; Vrieling, Klaas; Stiller, Mathias; Nagel, Doris; Rabeder, Gernot; Hofreiter, Michael; Sommer, Robert S

2013-06-01

The Late Quaternary was a time of rapid climatic oscillations and drastic environmental changes. In general, species can respond to such changes by behavioral accommodation, distributional shifts, ecophenotypic modifications (nongenetic), evolution (genetic) or ultimately face local extinction. How those responses manifested in the past is essential for properly predicting future ones especially as the current warm phase is further intensified by rising levels of atmospheric carbon dioxide. Here, we use ancient DNA (aDNA) and morphological features in combination with ecological niche modeling (ENM) to investigate genetic and nongenetic responses of Central European Palearctic shrews to past climatic change. We show that a giant form of shrew, previously described as an extinct Pleistocene Sorex species, represents a large ecomorph of the common shrew (Sorex araneus), which was replaced by populations from a different gene-pool and with different morphology after the Pleistocene Holocene transition. We also report the presence of the cold-adapted tundra shrew (S. tundrensis) in Central Europe. This species is currently restricted to Siberia and was hitherto unknown as an element of the Pleistocene fauna of Europe. Finally, we show that there is no clear correlation between climatic oscillations within the last 50 000 years and body size in shrews and conclude that a special nonanalogous situation with regard to biodiversity and food supply in the Late Glacial may have caused the observed large body size. © 2013 Blackwell Publishing Ltd.

The effects of captive rearing on the behavior of newly-released whooping cranes (Grus americana)

USGS Publications Warehouse

Kreger, M.D.; Hatfield, J.S.; Estevez, I.; Gee, G.F.; Clugston, D.A.

2005-01-01

Rearing treatments used in captivity to prepare animals for reintroduction to the wild may have a profound effect on behavior and, possibly, affect their survival after reintroduction. This study examined the behaviors of captive-reared whooping cranes (Grus americana) upon their release in Florida to determine if rearing treatments may affect the behavior of the birds and how these affect their chances of survival in the wild. Individually tagged birds were observed at the rearing facility, the U.S. Geological Survey Patuxent Wildlife Research Center in Maryland, from hatch to 20 weeks of age and at the release site in Central Florida for up to 6 weeks post release. The rearing treatments were parent reared (PR), hand reared (HR), and hand reared with exercise (HRE). Observations at the rearing facility are described in a previous paper. At the release site, each bird was observed for 5 min every morning (0700?1000 h) and late afternoon (1500?1800 h) during the 6-week study period. Our results indicated that most of the time, the n = 34 birds were foraging (46.03 ? 1.48%), followed by nonvigilant (20.89 ? 0.73%), vigilant (19.21 ? 0.72%), or performing comfort behaviors (11.61 ? 1.28%). Data were analyzed using mixed models repeated measures ANOVA. There were no significant behavioral differences between HR and HRE birds. PR birds were found in larger groups than HR birds during the first 2 weeks post release and greater than HR and HRE birds afterwards. This may be interpreted as an antipredator strategy for birds that relied on parental guidance during rearing. HR and HRE birds foraged more than PR birds during the first 2 weeks post release and PR birds were more vigilant during the first 2 weeks post release. Across rearing treatments, the percentages of time spent foraging and engaged in vigilant behaviors during rearing were positively correlated with their behavior upon release. If any of these behaviors can be demonstrated to have relevance for the survival of the whooping cranes after release then it may be possible to establish behavioral interventions to increase the frequencies of such behavior, so that they are perpetuated after release.

Late Maternal Deaths and Deaths from Sequelae of Obstetric Causes in the Americas from 1999 to 2013: A Trend Analysis.

PubMed

de Cosio, Federico G; Jiwani, Safia S; Sanhueza, Antonio; Soliz, Patricia N; Becerra-Posada, Francisco; Espinal, Marcos A

2016-01-01

Data on maternal deaths occurring after the 42 days postpartum reference time is scarce; the objective of this analysis is to explore the trend and magnitude of late maternal deaths and deaths from sequelae of obstetric causes in the Americas between 1999 and 2013, and to recommend including these deaths in the monitoring of the Sustainable Development Goals (SDGs). Exploratory data analysis enabled analyzing the magnitude and trend of late maternal deaths and deaths from sequelae of obstetric causes for seven countries of the Americas: Argentina, Brazil, Canada, Colombia, Cuba, Mexico and the United States. A Poisson regression model was developed to compare trends of late maternal deaths and deaths from sequelae of obstetric causes between two periods of time: 1999 to 2005 and 2006 to 2013; and to estimate the relative increase of these deaths in the two periods of time. The proportion of late maternal deaths and deaths from sequelae of obstetric causes ranged between 2.40% (CI 0.85% - 5.48%) and 18.68% (CI 17.06% - 20.47%) in the seven countries. The ratio of late maternal deaths and deaths from sequelae of obstetric causes per 100,000 live births has increased by two times in the region of the Americas in the period 2006-2013 compared to the period 1999-2005. The regional relative increase of late maternal death was 2.46 (p<0.0001) times higher in the second period compared to the first. Ascertainment of late maternal deaths and deaths from sequelae of obstetric causes has improved in the Americas since the early 2000's due to improvements in the quality of information and the obstetric transition. Late and obstetric sequelae maternal deaths should be included in the monitoring of the SDGs as well as in the revision of the International Classification of Diseases' 11th version (ICD-11).

Late Maternal Deaths and Deaths from Sequelae of Obstetric Causes in the Americas from 1999 to 2013: A Trend Analysis

PubMed Central

de Cosio, Federico G.; Sanhueza, Antonio; Soliz, Patricia N.; Becerra-Posada, Francisco; Espinal, Marcos A.

2016-01-01

Background Data on maternal deaths occurring after the 42 days postpartum reference time is scarce; the objective of this analysis is to explore the trend and magnitude of late maternal deaths and deaths from sequelae of obstetric causes in the Americas between 1999 and 2013, and to recommend including these deaths in the monitoring of the Sustainable Development Goals (SDGs). Methods Exploratory data analysis enabled analyzing the magnitude and trend of late maternal deaths and deaths from sequelae of obstetric causes for seven countries of the Americas: Argentina, Brazil, Canada, Colombia, Cuba, Mexico and the United States. A Poisson regression model was developed to compare trends of late maternal deaths and deaths from sequelae of obstetric causes between two periods of time: 1999 to 2005 and 2006 to 2013; and to estimate the relative increase of these deaths in the two periods of time. Findings The proportion of late maternal deaths and deaths from sequelae of obstetric causes ranged between 2.40% (CI 0.85% – 5.48%) and 18.68% (CI 17.06% – 20.47%) in the seven countries. The ratio of late maternal deaths and deaths from sequelae of obstetric causes per 100,000 live births has increased by two times in the region of the Americas in the period 2006-2013 compared to the period 1999-2005. The regional relative increase of late maternal death was 2.46 (p<0.0001) times higher in the second period compared to the first. Interpretation Ascertainment of late maternal deaths and deaths from sequelae of obstetric causes has improved in the Americas since the early 2000’s due to improvements in the quality of information and the obstetric transition. Late and obstetric sequelae maternal deaths should be included in the monitoring of the SDGs as well as in the revision of the International Classification of Diseases’ 11th version (ICD-11). PMID:27626277

Ecological consequences of human niche construction: Examining long-term anthropogenic shaping of global species distributions

PubMed Central

Boivin, Nicole L.; Zeder, Melinda A.; Fuller, Dorian Q.; Crowther, Alison; Larson, Greger; Erlandson, Jon M.; Denham, Tim; Petraglia, Michael D.

2016-01-01

The exhibition of increasingly intensive and complex niche construction behaviors through time is a key feature of human evolution, culminating in the advanced capacity for ecosystem engineering exhibited by Homo sapiens. A crucial outcome of such behaviors has been the dramatic reshaping of the global biosphere, a transformation whose early origins are increasingly apparent from cumulative archaeological and paleoecological datasets. Such data suggest that, by the Late Pleistocene, humans had begun to engage in activities that have led to alterations in the distributions of a vast array of species across most, if not all, taxonomic groups. Changes to biodiversity have included extinctions, extirpations, and shifts in species composition, diversity, and community structure. We outline key examples of these changes, highlighting findings from the study of new datasets, like ancient DNA (aDNA), stable isotopes, and microfossils, as well as the application of new statistical and computational methods to datasets that have accumulated significantly in recent decades. We focus on four major phases that witnessed broad anthropogenic alterations to biodiversity—the Late Pleistocene global human expansion, the Neolithic spread of agriculture, the era of island colonization, and the emergence of early urbanized societies and commercial networks. Archaeological evidence documents millennia of anthropogenic transformations that have created novel ecosystems around the world. This record has implications for ecological and evolutionary research, conservation strategies, and the maintenance of ecosystem services, pointing to a significant need for broader cross-disciplinary engagement between archaeology and the biological and environmental sciences. PMID:27274046

Amygdalo-cortical sprouting continues into early adulthood: implications for the development of normal and abnormal function during adolescence.

PubMed

Cunningham, Miles Gregory; Bhattacharyya, Sujoy; Benes, Francine Mary

2002-11-11

Adolescence is a critical stage for the development of emotional maturity and diverse forms of psychopathology. The posterior basolateral nucleus of the amygdala is known to mediate fear and anxiety and is important in assigning emotional valence to cognitive processes. The medial prefrontal cortex, a homologue of the human anterior cingulate cortex, mediates emotional, attentional, and motivational behaviors at the cortical level. We postulate that the development of connectivity between these two corticolimbic regions contributes to an enhanced integration of emotion and cognition during the postnatal period. In order to characterize the development of this relay, injections of the anterograde tracer biocytin were stereotaxically placed within the posterior basolateral nucleus of the amygdala of rats at successive postnatal time points (postnatal days 6-120). Labeled fibers in the medial prefrontal cortex were evaluated using a combination of brightfield, confocal, and electron microscopy. We found that the density of labeled fibers originating from the posterior basolateral nucleus shows a sharp curvilinear increase within layers II and V of the anterior cingulate cortex and the infralimbic subdivisions of medial prefrontal cortex during the late postweanling period. This increase was paralleled by a linear rise in the number of axospinous and axodendritic synapses present in the neuropil. Based on these results, we propose that late maturation of amygdalo-cortical connectivity may provide an anatomical basis for the development and integration of normal and possibly abnormal emotional behavior during adolescence and early adulthood. Copyright 2002 Wiley-Liss, Inc.

Meteorological effects on the daily activity patterns of tabanid biting flies in northern Queensland, Australia.

PubMed

Van Hennekeler, K; Jones, R E; Skerratt, L F; Muzari, M O; Fitzpatrick, L A

2011-03-01

Information on the daily activity patterns of tabanid flies is important in the development of strategies that decrease the risk of pathogens transmitted by them. In addition, this information is useful to maximize numbers of tabanids trapped during short-term studies and to target feeding behavior studies of certain tabanid species to their times of peak activity. The current study examined the effects of various meteorological factors on the daily activity patterns of common tropical species of tabanids in north Queensland. Each species studied responded differently to weather factors. Tabanus townsvilli Ricardo (Diptera: Tabanidae) was most active during late morning and early afternoon, whereas Pseudotabanus silvester (Bergroth) and Tabanus pallipennis Macquart were most active in the late afternoon. Tabanus dorsobimaculatus Macquart was most active in the morning and early afternoon. Data on daily activity patterns of tabanid flies indicates that in an area such as Townsville, North Queensland, where several species of tabanid are present concurrently in high numbers, the overlapping periods of high activity for these species indicate a high risk of pathogen transmission for most of the day (10.00-19.00 hours). Similarly, because each species responds differently to weather variables, only extreme weather conditions are likely to inhibit activity of all species. These data also indicate that for maximal results, trapping and feeding behavior studies should be tailored to the preferred activity period of the species under investigation. © 2010 The Authors. Medical and Veterinary Entomology © 2010 The Royal Entomological Society.

Ecological consequences of human niche construction: Examining long-term anthropogenic shaping of global species distributions.

PubMed

Boivin, Nicole L; Zeder, Melinda A; Fuller, Dorian Q; Crowther, Alison; Larson, Greger; Erlandson, Jon M; Denham, Tim; Petraglia, Michael D

2016-06-07

The exhibition of increasingly intensive and complex niche construction behaviors through time is a key feature of human evolution, culminating in the advanced capacity for ecosystem engineering exhibited by Homo sapiens A crucial outcome of such behaviors has been the dramatic reshaping of the global biosphere, a transformation whose early origins are increasingly apparent from cumulative archaeological and paleoecological datasets. Such data suggest that, by the Late Pleistocene, humans had begun to engage in activities that have led to alterations in the distributions of a vast array of species across most, if not all, taxonomic groups. Changes to biodiversity have included extinctions, extirpations, and shifts in species composition, diversity, and community structure. We outline key examples of these changes, highlighting findings from the study of new datasets, like ancient DNA (aDNA), stable isotopes, and microfossils, as well as the application of new statistical and computational methods to datasets that have accumulated significantly in recent decades. We focus on four major phases that witnessed broad anthropogenic alterations to biodiversity-the Late Pleistocene global human expansion, the Neolithic spread of agriculture, the era of island colonization, and the emergence of early urbanized societies and commercial networks. Archaeological evidence documents millennia of anthropogenic transformations that have created novel ecosystems around the world. This record has implications for ecological and evolutionary research, conservation strategies, and the maintenance of ecosystem services, pointing to a significant need for broader cross-disciplinary engagement between archaeology and the biological and environmental sciences.